WorldWideScience

Sample records for loss reduction perspective

  1. Food loss reduction from an environmental, socio-economic and consumer perspective - The case of the Swiss potato market.

    Science.gov (United States)

    Willersinn, Christian; Mouron, Patrik; Mack, Gabriele; Siegrist, Michael

    2017-01-01

    Potatoes are one of the commodities with the highest loss shares along the entire supply chain. In the present study, we analyzed six potential loss reduction scenarios concerning their environmental-socio-economic sustainability compared with the current situation by using the "SustainOS" methodology. For this purpose, life cycle assessments, full-cost calculations and an online consumer survey were conducted. Environmental improvements through loss reduction were rather small and did not cross limits of significance, but the socio-economic performance of the entire supply chain can be improved considerably. Pearson correlation coefficients and linear regression analyses were used to predict the influence of specific subjective items like the intention to avoid food loss, knowledge related to food loss and consumers' price sensitivity on the assigned preference. Results show that perceived risks, perceived inconvenience and the general acceptance of loss-reducing instruments influence consumers' preferences. Altogether, only three out of six tested scenarios seem realistic: selling unwashed potatoes in a lightproof box, selling unpacked potatoes, and improved quality sorting at farms. For two of the other scenarios, consumers significantly indicated their refusal even if losses decreased considerably, whereas the sixth scenario was unfavorable from a socio-economic perspective. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. A scoping study on the costs of indoor air quality illnesses:an insurance loss reduction perspective

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Allan; Vine, Edward L.

    1998-08-31

    The incidence of commercial buildings with poor indoor air quality (IAQ), and the frequency of litigation over the effects of poor IAQ is increasing. If so, these increases have ramifications for insurance carriers, which pay for many of the costs of health care and general commercial liability. However, little is known about the actual costs to insurance companies from poor IAQ in buildings. This paper reports on the results of a literature search of buildings-related, business and legal databases, and interviews with insurance and risk management representatives aimed at finding information on the direct costs to the insurance industry of poor building IAQ, as well as the costs of litigation. The literature search and discussions with insurance and risk management professionals reported in this paper turned up little specific information about the costs of IAQ-related problems to insurance companies. However, those discussions and certain articles in the insurance industry press indicate that there is a strong awareness and growing concern over the "silent crisis" of IAQ and its potential to cause large industry losses, and that a few companies are taking steps to address this issue. The source of these losses include both direct costs to insurers from paying health insurance and professional liability claims, as weIl as the cost of litigation. In spite of the lack of data on how IAQ-related health problems affect their business, the insurance industry has taken the anecdotal evidence about their reality seriously enough to alter their policies in ways that have lessened their exposure. We conclude by briefly discussing four activities that need to be addressed in the near future: (1) quantifying IAQ-related insurance costs by sector, (2) educating the insurance industry about the importance of IAQ issues, (3) examining IAQ impacts on the insurance industry in the residential sector, and (4) evaluating the relationship between IAQ improvements and their impact on

  3. Recurrent pregnancy loss: current perspectives

    Directory of Open Access Journals (Sweden)

    El Hachem H

    2017-05-01

    Full Text Available Hady El Hachem,1,2 Vincent Crepaux,3 Pascale May-Panloup,4 Philippe Descamps,3 Guillaume Legendre,3 Pierre-Emmanuel Bouet3 1Department of Reproductive Medicine, Ovo Clinic, Montréal, QC, Canada; 2Department of Obstetrics and Gynecology, University of Montreal, Montréal, QC, Canada; 3Department of Obstetrics and Gynecology, Angers University Hopsital, Angers, France; 4Department of Reproductive Biology, Angers University Hospital, Angers, France Abstract: Recurrent pregnancy loss is an important reproductive health issue, affecting 2%–5% of couples. Common established causes include uterine anomalies, antiphospholipid syndrome, hormonal and metabolic disorders, and cytogenetic abnormalities. Other etiologies have been proposed but are still considered controversial, such as chronic endometritis, inherited thrombophilias, luteal phase deficiency, and high sperm DNA fragmentation levels. Over the years, evidence-based treatments such as surgical correction of uterine anomalies or aspirin and heparin for antiphospholipid syndrome have improved the outcomes for couples with recurrent pregnancy loss. However, almost half of the cases remain unexplained and are empirically treated using progesterone supplementation, anticoagulation, and/or immunomodulatory treatments. Regardless of the cause, the long-term prognosis of couples with recurrent pregnancy loss is good, and most eventually achieve a healthy live birth. However, multiple pregnancy losses can have a significant psychological toll on affected couples, and many efforts are being made to improve treatments and decrease the time needed to achieve a successful pregnancy. This article reviews the established and controversial etiologies, and the recommended therapeutic strategies, with a special focus on unexplained recurrent pregnancy losses and the empiric treatments used nowadays. It also discusses the current role of preimplantation genetic testing in the management of recurrent pregnancy

  4. REDUCTIONS WITHOUT REGRET: HISTORICAL PERSPECTIVES

    Energy Technology Data Exchange (ETDEWEB)

    Swegle, J.; Tincher, D.

    2013-09-09

    This is the first of three papers (in addition to an introductory summary) aimed at providing a framework for evaluating future reductions or modifications of the U.S. nuclear force, first by considering previous instances in which nuclear-force capabilities were eliminated; second by looking forward into at least the foreseeable future at the features of global and regional deterrence (recognizing that new weapon systems currently projected will have expected lifetimes stretching beyond our ability to predict the future); and third by providing examples of past or possible undesirable outcomes in the shaping of the future nuclear force, as well as some closing thoughts for the future. This paper examines the circumstances and consequences of the elimination of The INF-range Pershing II ballistic missile and Gryphon Ground-Launched Cruise Missile (GLCM), deployed by NATO under a dual-track strategy to counter Soviet intermediate-range missiles while pursuing negotiations to limit or eliminate all of these missiles. The Short-Range Attack Missile (SRAM), which was actually a family of missiles including SRAM A, SRAM B (never deployed), and SRAM II and SRAM T, these last two cancelled during an over-budget/behind-schedule development phase as part of the Presidential Nuclear Initiatives of 1991 and 1992. The nuclear-armed version of the Tomahawk Land-Attack Cruise Missile (TLAM/N), first limited to shore-based storage by the PNIs, and finally eliminated in deliberations surrounding the 2010 Nuclear Posture Review Report. The Missile-X (MX), or Peacekeeper, a heavy MIRVed ICBM, deployed in fixed silos, rather than in an originally proposed mobile mode. Peacekeeper was likely intended as a bargaining chip to facilitate elimination of Russian heavy missiles. The plan failed when START II did not enter into force, and the missiles were eliminated at the end of their intended service life. The Small ICBM (SICBM), or Midgetman, a road-mobile, single-warhead missile for

  5. Distribution Loss Reduction by Household Consumption Coordination in Smart Grids

    DEFF Research Database (Denmark)

    Juelsgaard, Morten; Andersen, Palle; Wisniewski, Rafal

    2014-01-01

    for coordinating consumption of electrical energy within the community, with the purpose of reducing grid loading and active power losses. For this we present a simplified model of the electrical grid, including system losses and capacity constraints. Coordination is performed in a distributed fashion, where each...... are obeyed. These objectives are enforced by coordinating consumers through a nonlinear penalty on power consumption. We present simulation test-cases, illustrating that significant reduction of active losses, can be obtained by such coordination. The distributed optimization algorithm employs...

  6. Reactive power compensation and loss reduction in large industrial enterprises

    Energy Technology Data Exchange (ETDEWEB)

    Jovanovic, S; Gajic, B; Mijailovic, S [Institute Nikola Tesla, Beograd (Yugoslavia)

    1991-12-01

    This paper considers the reactive power compensation and the active power and energy loss reduction of large radial power networks in the Serbian mine and smelting industry. It gives an efficient optimization procedure for positioning and sizing capacitors in large industrial systems integrated with a simple network analysis method. (Author).

  7. Quantifying food losses and the potential for reduction in Switzerland.

    Science.gov (United States)

    Beretta, Claudio; Stoessel, Franziska; Baier, Urs; Hellweg, Stefanie

    2013-03-01

    A key element in making our food systems more efficient is the reduction of food losses across the entire food value chain. Nevertheless, food losses are often neglected. This paper quantifies food losses in Switzerland at the various stages of the food value chain (agricultural production, postharvest handling and trade, processing, food service industry, retail, and households), identifies hotspots and analyses the reasons for losses. Twenty-two food categories are modelled separately in a mass and energy flow analysis, based on data from 31 companies within the food value chain, and from public institutions, associations, and from the literature. The energy balance shows that 48% of the total calories produced (edible crop yields at harvest time and animal products, including slaughter waste) is lost across the whole food value chain. Half of these losses would be avoidable given appropriate mitigation measures. Most avoidable food losses occur at the household, processing, and agricultural production stage of the food value chain. Households are responsible for almost half of the total avoidable losses (in terms of calorific content). Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Use of Hydraulic Model for Water Loss Reduction

    OpenAIRE

    Mindaugas Rimeika; Anželika Jurkienė

    2016-01-01

    Hydraulic modeling is the modern way to apply world water engineering experience in every day practice. Hydraulic model is an effective tool in order to perform analysis of water supply system, optimization of its operation, assessment of system efficiency potential, evaluation of water network development, fire flow capabilities, energy saving opportunities and water loss reduction and ect. Hydraulic model shall include all possible engineering elements and devices allocated in a real water ...

  9. IGBT Dynamic Loss Reduction through Device Level Soft Switching

    Directory of Open Access Journals (Sweden)

    Lan Ma

    2018-05-01

    Full Text Available Due to its low conduction loss, hence high current ratings, as well as low cost, Silicon Insulated Gate Bipolar Transistor (Si IGBT is widely used in high power applications. However, its switching frequency is generally low because of relatively large switching losses. Silicon carbide Metal-Oxide-Semiconductor Field-Effect Transistor (SiC MOSFET is much more superior due to their fast switching speed, which is determined by the internal parasitic capacitance instead of the stored charges, like the IGBT. By the combination of SiC MOSFET and Si IGBT, this paper presents a novel series hybrid switching method to achieve IGBT’s dynamic switching loss reduction by switching under Zero Voltage Hard Current (ZVHC turn-on and Zero Current Hard Voltage (ZCHV turn-off conditions. Both simulation and experimental results of IGBT are carried out, which shows that the soft switching of IGBT has been achieved both in turn-on and turn-off period. Thus 90% turn-on loss and 57% turn-off loss are reduced. Two different IGBTs’ test results are also provided to study the modulation parameter’s effect on the turn-off switching loss. Furthermore, with the consideration of voltage and current transient states, a new soft switching classification is proposed. At last, another improved modulation and Highly Efficient and Reliable Inverter Concept (HERIC inverter are given to validate the effectiveness of the device level hybrid soft switching method application.

  10. Noise-induced hearing loss: a recreational noise perspective.

    Science.gov (United States)

    Ivory, Robert; Kane, Rebecca; Diaz, Rodney C

    2014-10-01

    This review will discuss the real-world risk factors involved in noise-induced hearing loss as a result of common and popular recreational activities prone to mid and high levels of noise exposure. Although there are currently no interventional measures available to reverse or mitigate preexisting hearing loss from noise, we discuss the vital importance of hearing loss prevention from noise exposure avoidance and reduction. Despite a seeming understanding of the effects of noise exposure from various recreational activities and devices, a large percentage of the general public who is at risk of such noise-induced hearing loss still chooses to refrain from using hearing protection instruments. While occupational exposures pose the greatest traditional risk to hearing conservation in selected workers, recreational risk factors for noise-induced hearing loss may be more insidious in overall effect given the indifferent attitude of much of the general public and particularly our youths toward hearing protection during recreational activities. Active counseling regarding the consequences of excessive noise exposure and the potential benefits to hearing from usage of hearing protection instruments is critical to providing best possible care in the hearing health professions.

  11. DGA-based VAR rescheduling for transmission loss reduction

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, S. [Indian Inst. of Technology, Delhi (India); Taylor, G.A. [Brunel Univ., London (United Kingdom). Brunel Inst. of Power Systems; Reddy, J.B.V. [Government of India, New Delhi (India). Dept. of Science and Technology; Naeem, M.H. [Multimedia Univ. (Malaysia). Faculty of Engineering

    2009-07-01

    Power losses in power transmission lines can be minimized by adjusting transformer taps and switchable VAR sources. Optimal power flow (OPF) is a static, nonlinear, multi-objective optimization challenge in which the optimal settings of control variables must be determined for minimizing the cost of generation, emissions, transmission losses and voltage and power flow deviations. OPF is important in power system operation because a small savings per hour can mean a large annual savings. This paper presented a method to reduce transmission power losses using a Differential Genetic Algorithm (DGA) for VAR rescheduling. The New England 39-bus power system was used as a test case. Power losses were minimized by changing the tap settings of various transformers and by varying the injected reactive power. The paper showed that certain buses in the system can improve the voltage profile and reduce transmission losses through reactive power injections from capacitor banks. In this study, minimum reactive power output of generators was maintained at zero to ensure that the generators did not draw reactive power. The DGA was shown to produce better results than the Conventional Genetic Algorithm in terms of power loss minimization. 12 refs., 1 tab., 2 figs.

  12. Reduction of water losses by rehabilitation of water distribution network.

    Science.gov (United States)

    Güngör, Mahmud; Yarar, Ufuk; Firat, Mahmut

    2017-09-11

    Physical or real losses may be indicated as the most important component of the water losses occurring in a water distribution network (WDN). The objective of this study is to examine the effects of piping material management and network rehabilitation on the physical water losses and water losses management in a WDN. For this aim, the Denizli WDN consisting of very old pipes that have exhausted their economic life is selected as the study area. The fact that the current network is old results in the decrease of pressure strength, increase of failure intensity, and inefficient use of water resources thus leading to the application of the rehabilitation program. In Denizli, network renewal works have been carried out since the year 2009 under the rehabilitation program. It was determined that the failure rate at regions where network renewal constructions have been completed decreased down to zero level. Renewal of piping material enables the minimization of leakage losses as well as the failure rate. On the other hand, the system rehabilitation has the potential to amortize itself in a very short amount of time if the initial investment cost of network renewal is considered along with the operating costs of the old and new systems, as well as water loss costs. As a result, it can be stated that renewal of piping material in water distribution systems, enhancement of the physical properties of the system, provide significant contributions such as increase of water and energy efficiency and more effective use of resources.

  13. FACTORS AFFECTING BLOOD LOSS DURING OpEN REDUCTION ...

    African Journals Online (AJOL)

    The use of diathermy and positioning of the patient in a way that encourages free venous drainage at the operative site (1) is a practical and inexpensive way of minimising blood loss during surgery. The operative site should be a little above the level of the heart (1). Good anaesthetic technique reduces episodes of.

  14. Reduction of losses in linacs for protons or heavy ions

    International Nuclear Information System (INIS)

    Claus, J.

    1977-01-01

    It is necessary to minimize the beam losses in linacs for high average currents in order to avoid serious problems due to radiation damage, dissipation and radio activation of the accelerator structure. A large part of the losses in existing linacs is due to incomplete bunching of the injected beam. Proposed improvements generally appear to be deficient in one or more respects if applied to linacs with conventional frequencies, injection energies and current densities. By preceding the linac proper with an accelerating structure and an energy analyzer, it becomes possible to separate the particles that remained outside the buckets from those that are inside so that they can be dumped in a controlled manner

  15. Reductions in global biodiversity loss predicted from conservation spending

    Science.gov (United States)

    Waldron, Anthony; Miller, Daniel C.; Redding, Dave; Mooers, Arne; Kuhn, Tyler S.; Nibbelink, Nate; Roberts, J. Timmons; Tobias, Joseph A.; Gittleman, John L.

    2017-11-01

    Halting global biodiversity loss is central to the Convention on Biological Diversity and United Nations Sustainable Development Goals, but success to date has been very limited. A critical determinant of success in achieving these goals is the financing that is committed to maintaining biodiversity; however, financing decisions are hindered by considerable uncertainty over the likely impact of any conservation investment. For greater effectiveness, we need an evidence-based model that shows how conservation spending quantitatively reduces the rate of biodiversity loss. Here we demonstrate such a model, and empirically quantify how conservation investment between 1996 and 2008 reduced biodiversity loss in 109 countries (signatories to the Convention on Biological Diversity and Sustainable Development Goals), by a median average of 29% per country. We also show that biodiversity changes in signatory countries can be predicted with high accuracy, using a dual model that balances the effects of conservation investment against those of economic, agricultural and population growth (human development pressures). Decision-makers can use this model to forecast the improvement that any proposed biodiversity budget would achieve under various scenarios of human development pressure, and then compare these forecasts to any chosen policy target. We find that the impact of spending decreases as human development pressures grow, which implies that funding may need to increase over time. The model offers a flexible tool for balancing the Sustainable Development Goals of human development and maintaining biodiversity, by predicting the dynamic changes in conservation finance that will be needed as human development proceeds.

  16. Reductions in global biodiversity loss predicted from conservation spending.

    Science.gov (United States)

    Waldron, Anthony; Miller, Daniel C; Redding, Dave; Mooers, Arne; Kuhn, Tyler S; Nibbelink, Nate; Roberts, J Timmons; Tobias, Joseph A; Gittleman, John L

    2017-11-16

    Halting global biodiversity loss is central to the Convention on Biological Diversity and United Nations Sustainable Development Goals, but success to date has been very limited. A critical determinant of success in achieving these goals is the financing that is committed to maintaining biodiversity; however, financing decisions are hindered by considerable uncertainty over the likely impact of any conservation investment. For greater effectiveness, we need an evidence-based model that shows how conservation spending quantitatively reduces the rate of biodiversity loss. Here we demonstrate such a model, and empirically quantify how conservation investment reduced biodiversity loss in 109 countries (signatories to the Convention on Biological Diversity and Sustainable Development Goals), by a median average of 29% per country between 1996 and 2008. We also show that biodiversity changes in signatory countries can be predicted with high accuracy, using a dual model that balances the effects of conservation investment against those of economic, agricultural and population growth (human development pressures). Decision-makers can use this model to forecast the improvement that any proposed biodiversity budget would achieve under various scenarios of human development pressure, and then compare these forecasts to any chosen policy target. We find that the impact of spending decreases as human development pressures grow, which implies that funding may need to increase over time. The model offers a flexible tool for balancing the Sustainable Development Goals of human development and maintaining biodiversity, by predicting the dynamic changes in conservation finance that will be needed as human development proceeds.

  17. Reduction of Oxidative Melt Loss of Aluminum and Its Alloys

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Subodh K. Das; Shridas Ningileri

    2006-03-17

    This project led to an improved understanding of the mechanisms of dross formation. The microstructural evolution in industrial dross samples was determined. Results suggested that dross that forms in layers with structure and composition determined by the local magnesium concentration alone. This finding is supported by fundamental studies of molten metal surfaces. X-ray photoelectron spectroscopy data revealed that only magnesium segregates to the molten aluminum alloy surface and reacts to form a growing oxide layer. X-ray diffraction techniques that were using to investigate an oxidizing molten aluminum alloy surface confirmed for the first time that magnesium oxide is the initial crystalline phase that forms during metal oxidation. The analytical techniques developed in this project are now available to investigate other molten metal surfaces. Based on the improved understanding of dross initiation, formation and growth, technology was developed to minimize melt loss. The concept is based on covering the molten metal surface with a reusable physical barrier. Tests in a laboratory-scale reverberatory furnace confirmed the results of bench-scale tests. The main highlights of the work done include: A clear understanding of the kinetics of dross formation and the effect of different alloying elements on dross formation was obtained. It was determined that the dross evolves in similar ways regardless of the aluminum alloy being melted and the results showed that amorphous aluminum nitride forms first, followed by amorphous magnesium oxide and crystalline magnesium oxide in all alloys that contain magnesium. Evaluation of the molten aluminum alloy surface during melting and holding indicated that magnesium oxide is the first crystalline phase to form during oxidation of a clean aluminum alloy surface. Based on dross evaluation and melt tests it became clear that the major contributing factor to aluminum alloy dross was in the alloys with Mg content. Mg was

  18. Resource Loss and Naturalistic Reduction of PTSD among Inner-City Women

    Science.gov (United States)

    Walter, Kristen H.; Hobfoll, Stevan E.

    2009-01-01

    Halting the process of psychosocial and material resource loss has been theorized as being associated with the reduction of posttraumatic stress disorder (PTSD). This study examines how the limiting of resource loss is related to alleviation of PTSD symptoms among 102 inner-city women, who originally met diagnostic criteria for PTSD after…

  19. Effect of reduction of mechanical losses in AC superconducting coils having various FRP bobbins

    International Nuclear Information System (INIS)

    Sekine, N.; Tada, S.; Higuchi, T.; Takao, T.; Yamanaka, A.; Fukui, S.

    2004-01-01

    We have demonstrated in our previous works that a use of the particular structural material for superconducting coils was effective to mechanical-loss reduction under AC operation. In this study, we measured losses to investigate influence of the mechanical losses in the coils having various fiber reinforced plastics (FRPs) with different thermal expansion coefficients. The losses were small in the coils whose winding tension at coil-operating temperature were strong, on the contrary, the losses of the coil having the weak winding tension were large. The coil having the strongest winding tension at liquid helium temperature showed the smallest loss in all coils, and the loss agreed with a value from the Norris's analysis. We think that the mechanical loss becomes almost zero in this coil since the strong tension can prevent the periodic vibration of the superconducting wire. The dependence of the loss on the difference in surface conditions of the materials of the superconducting coil's bobbins was not observed, however, the mechanical losses in AC coils strongly depended on the winding tensions at cryogenic temperature

  20. Water Loss Reduction as the Basis of Good Water Supply Companies’ Management

    Directory of Open Access Journals (Sweden)

    Ociepa-Kubicka Agnieszka

    2017-01-01

    Full Text Available Companies using water distribution systems to reduce the operating costs and increase the reliability of water supply systems, as well as to protect disposable water resources, must search for ways to reduce water losses. The article points out the economic and environmental aspects of water losses. The possibilities of using international water loss assessment standards have been analysed. The reflections presented in the paper refer to the current trends and world standards in the field of water distribution systems management. The article presents the results and analysis of water losses for the water supply network operated by the Water Supply and Sewerage Company in Gliwice (Przedsiębiorstwo Wodociągów i Kanalizacji w Gliwicach, PWiK. The losses were determined on the basis of numerous indicators and compared with other distribution systems. At present, most indicators of water loss are at a very good or good level. The Infrastructure Leakage Index (ILI, as one of the most reliable loss indicators for the surveyed distribution system, assumed values from 3.33 in 2012 to 2.06 in 2015. The recent drop in ILI values indicates the effectiveness of the Company's strategy for water leakage reduction. The success comprises a number of undertakings, such as ongoing monitoring, pressure reduction and stabilisation, repairs and replacement of the most emergency wires.

  1. Water Loss Reduction as the Basis of Good Water Supply Companies' Management

    Science.gov (United States)

    Ociepa-Kubicka, Agnieszka; Wilczak, Krzysztof

    2017-10-01

    Companies using water distribution systems to reduce the operating costs and increase the reliability of water supply systems, as well as to protect disposable water resources, must search for ways to reduce water losses. The article points out the economic and environmental aspects of water losses. The possibilities of using international water loss assessment standards have been analysed. The reflections presented in the paper refer to the current trends and world standards in the field of water distribution systems management. The article presents the results and analysis of water losses for the water supply network operated by the Water Supply and Sewerage Company in Gliwice (Przedsiębiorstwo Wodociągów i Kanalizacji w Gliwicach, PWiK). The losses were determined on the basis of numerous indicators and compared with other distribution systems. At present, most indicators of water loss are at a very good or good level. The Infrastructure Leakage Index (ILI), as one of the most reliable loss indicators for the surveyed distribution system, assumed values from 3.33 in 2012 to 2.06 in 2015. The recent drop in ILI values indicates the effectiveness of the Company's strategy for water leakage reduction. The success comprises a number of undertakings, such as ongoing monitoring, pressure reduction and stabilisation, repairs and replacement of the most emergency wires.

  2. Optimal reconfiguration-based dynamic tariff for congestion management and line loss reduction in distribution networks

    DEFF Research Database (Denmark)

    Huang, Shaojun; Wu, Qiuwei; Cheng, Lin

    2016-01-01

    This paper presents an optimal reconfiguration-based dynamic tariff (DT) method for congestion management and line loss reduction in distribution networks with high penetration of electric vehicles. In the proposed DT concept, feeder reconfiguration (FR) is employed through mixed integer programm...

  3. Magnetic losses reduction in grain oriented silicon steel by pulse and continuous fiber laser processing

    Science.gov (United States)

    Petryshynets, Ivan; Kováč, František; Puchý, Viktor; Šebek, Martin; Füzer, Ján; Kollár, Peter

    2018-04-01

    The present paper shows the impact of different laser scribing conditions on possible reduction of magnetic losses in grain oriented electrical steel sheets. The experimental Fe-3%Si steel was taken from industrial line after final box annealing. The surface of investigated steel was subjected to fiber laser processing using both pulse and continuous scribing regimes in order to generate residual thermal stresses inducing the magnetic domains structure refinement. The magnetic losses of experimental samples before and after individual laser scribing regimes were tested in AC magnetic field with 50Hz frequency and induction of 1.5T. The most significant magnetic losses reduction of 38% was obtained at optimized conditions of continuous laser scribing regime. A semi quantitative relationship has been found between the domain patterns and the used fiber laser processing.

  4. Magnetic losses reduction in grain oriented silicon steel by pulse and continuous fiber laser processing

    Directory of Open Access Journals (Sweden)

    Ivan Petryshynets

    2018-04-01

    Full Text Available The present paper shows the impact of different laser scribing conditions on possible reduction of magnetic losses in grain oriented electrical steel sheets. The experimental Fe-3%Si steel was taken from industrial line after final box annealing. The surface of investigated steel was subjected to fiber laser processing using both pulse and continuous scribing regimes in order to generate residual thermal stresses inducing the magnetic domains structure refinement. The magnetic losses of experimental samples before and after individual laser scribing regimes were tested in AC magnetic field with 50Hz frequency and induction of 1.5T. The most significant magnetic losses reduction of 38% was obtained at optimized conditions of continuous laser scribing regime. A semi quantitative relationship has been found between the domain patterns and the used fiber laser processing.

  5. Evaluation of levee setbacks for flood-loss reduction, Middle Mississippi River, USA

    Science.gov (United States)

    Dierauer, Jennifer; Pinter, Nicholas; Remo, Jonathan W. F.

    2012-07-01

    SummaryOne-dimensional hydraulic modeling and flood-loss modeling were used to test the effectiveness of levee setbacks for flood-loss reduction along the Middle Mississippi River (MMR). Four levee scenarios were assessed: (1) the present-day levee configuration, (2) a 1000 m levee setback, (3) a 1500 m levee setback, and (4) an optimized setback configuration. Flood losses were estimated using FEMA's Hazus-MH (Hazards US Multi-Hazard) loss-estimation software on a structure-by-structure basis for a range of floods from the 2- to the 500-year events. These flood-loss estimates were combined with a levee-reliability model to calculate probability-weighted damage estimates. In the simplest case, the levee setback scenarios tested here reduced flood losses compared to current conditions for large, infrequent flooding events but increased flood losses for smaller, more frequent flood events. These increases occurred because levee protection was removed for some of the existing structures. When combined with buyouts of unprotected structures, levee setbacks reduced flood losses for all recurrence intervals. The "optimized" levee setback scenario, involving a levee configuration manually planned to protect existing high-value infrastructure, reduced damages with or without buyouts. This research shows that levee setbacks in combination with buyouts are an economically viable approach for flood-risk reduction along the study reach and likely elsewhere where levees are widely employed for flood control. Designing a levee setback around existing high-value infrastructure can maximize the benefit of the setback while simultaneously minimizing the costs. The optimized levee setback scenario analyzed here produced payback periods (costs divided by benefits) of less than 12 years. With many aging levees failing current inspections across the US, and flood losses spiraling up over time, levee setbacks are a viable solution for reducing flood exposure and flood levels.

  6. Shock treatment, brain damage, and memory loss: a neurological perspective.

    Science.gov (United States)

    Friedberg, J

    1977-09-01

    The author reviews reports of neuropathology resulting from electroconvulsive therapy in experimental animals and humans. Although findings of petechial hemorrhage, gliosis, and neuronal loss were well established in the decade following the introduction of ECT, they have been generally ignored since then. ECT produces characteristic EEG changes and severe retrograde amnesia, as well as other more subtle effects on memory and learning. The author concludes that ECT results in brain disease and questions whether doctors should offer brain damage to their patients.

  7. Noise-induced hearing loss: an occupational medicine perspective.

    Science.gov (United States)

    Stucken, Emily Z; Hong, Robert S

    2014-10-01

    Up to 30 million workers in the United States are exposed to potentially detrimental levels of noise. Although reliable medications for minimizing or reversing noise-induced hearing loss (NIHL) are not currently available, NIHL is entirely preventable. The purpose of this article is to review the epidemiology and pathophysiology of occupational NIHL. We will focus on at-risk populations and discuss prevention programs. Current prevention programs focus on reducing inner ear damage by minimizing environmental noise production and through the use of personal hearing protective devices. NIHL is the result of a complex interaction between environmental factors and patient factors, both genetic and acquired. The effects of noise exposure are specific to an individual. Trials are currently underway evaluating the role of antioxidants in protection from, and even reversal of, NIHL. Occupational NIHL is the most prevalent occupational disease in the United States. Occupational noise exposures may contribute to temporary or permanent threshold shifts, although even temporary threshold shifts may predispose an individual to eventual permanent hearing loss. Noise prevention programs are paramount in reducing hearing loss as a result of occupational exposures.

  8. Mitochondrial genome evolution in Alismatales: Size reduction and extensive loss of ribosomal protein genes

    DEFF Research Database (Denmark)

    Petersen, Gitte; Cuenca, Argelia; Zervas, Athanasios

    2017-01-01

    The order Alismatales is a hotspot for evolution of plant mitochondrial genomes characterized by remarkable differences in genome size, substitution rates, RNA editing, retrotranscription, gene loss and intron loss. Here we have sequenced the complete mitogenomes of Zostera marina and Stratiotes...... aloides, which together with previously sequenced mitogenomes from Butomus and Spirodela, provide new evolutionary evidence of genome size reduction, gene loss and transfer to the nucleus. The Zostera mitogenome includes a large portion of DNA transferred from the plastome, yet it is the smallest known...... mitogenome from a non-parasitic plant. Using a broad sample of the Alismatales, the evolutionary history of ribosomal protein gene loss is analyzed. In Zostera almost all ribosomal protein genes are lost from the mitogenome, but only some can be found in the nucleus....

  9. Are "Habitable" Exoplanets Really Habitable? -A perspective from atmospheric loss

    Science.gov (United States)

    Dong, C.; Huang, Z.; Jin, M.; Lingam, M.; Ma, Y. J.; Toth, G.; van der Holst, B.; Airapetian, V.; Cohen, O.; Gombosi, T. I.

    2017-12-01

    In the last two decades, the field of exoplanets has witnessed a tremendous creative surge. Research in exoplanets now encompasses a wide range of fields ranging from astrophysics to heliophysics and atmospheric science. One of the primary objectives of studying exoplanets is to determine the criteria for habitability, and whether certain exoplanets meet these requirements. The classical definition of the Habitable Zone (HZ) is the region around a star where liquid water can exist on the planetary surface given sufficient atmospheric pressure. However, this definition largely ignores the impact of the stellar wind and stellar magnetic activity on the erosion of an exoplanet's atmosphere. Amongst the many factors that determine habitability, understanding the mechanisms of atmospheric loss is of paramount importance. We will discuss the impact of exoplanetary space weather on climate and habitability, which offers fresh insights concerning the habitability of exoplanets, especially those orbiting M-dwarfs, such as Proxima b and the TRAPPIST-1 system. For each case, we will demonstrate the importance of the exoplanetary space weather on atmospheric ion loss and habitability.

  10. Reduction of greenhouse gas emissions resulting from decreased losses in the conductors of an electrical installation

    International Nuclear Information System (INIS)

    Lobão, J.A.; Devezas, T.; Catalão, J.P.S.

    2014-01-01

    Highlights: • A new software application is provided in this paper. • The efficient investment in street lighting and industrial and domestic electrical equipment is analyzed. • The reduction of losses in the conductors of electrical installations is properly accounted for. • The reduction of CO 2 emitted into the atmosphere is also determined. - Abstract: The activities of the electricity sector in production and consumption have implications in almost all environmental problems of today. The main environmental impacts occur during the production of electricity, mainly due to the emission of air pollutants, which is directly linked to climate change that has been observed over time. Ambitious climate change mitigation requires significant changes in many economic sectors, in particular in the production and consumption of energy. Considering that the primary energy consumption has increased, doubling since the 1970s, and in particular the consumption of electricity has had a sharper increase, nearly quadrupling in the same period, all measures that can mitigate environmental impacts on both the supply and demand sides of electricity are of interest. This paper introduces a new software application that analyses efficient investment in street lighting and industrial and domestic electrical equipment, accounting for the reduction of losses in the conductors of electrical installations, which is usually neglected. It also determines the reduction of CO 2 emitted into the atmosphere, which contributes to the reduction of emissions of greenhouse gases from a country or particular product

  11. Smartphone applications to aid weight loss and management: current perspectives

    Directory of Open Access Journals (Sweden)

    Sutton EF

    2016-07-01

    Full Text Available Elizabeth F Sutton, Leanne M Redman Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA Abstract: The development and dissemination of smart devices has cultivated a global environment of hyperconnectivity and increased our access to information. The paralleled launch and success of the Mobile Health industry has created a market of commercially available applications or “apps” along with tools or sensors, which allow the user to receive and collect personal health information. Apps and accompanying tools now allow an individual to “self-digitize” and, pertaining to weight management, monitor their body weight, caloric intake, physical activity, and more. These products possess the ability to improve the scalability of traditional in-person weight management services considering their near ubiquity, affordability, and capability to deliver information directly and personally to the user. However, similar to the dietary supplement market, the anecdotal value of these products has driven their popularity and acceptance by the general public without requirement of scientific validation or, in the area of weight management or diet/exercise, validation of the safety and efficacy by the Food and Drug Administration prior to market launch. By conducting a literature and clinical trial search, we found remarkably few active, completed, or published studies testing the efficacy of smart device applications using randomized controlled trials. Research efforts must be focused on illuminating the efficacy of behavioral interventions and remote self-monitoring for weight loss/maintenance treatment with true, randomized controlled trials. Keywords: smartphone, mobile phone, application, app, weight, weight loss, weight maintenance

  12. EVALUATING DEGREE OF ACTIVE POWER LOSSES REDUCTION IN THE ELECTRIC POWER LINES WITH REACTIVE POWER COMPENSATION

    Directory of Open Access Journals (Sweden)

    V. N. Radkevich

    2016-01-01

    Full Text Available The paper considers evaluation procedure for the degree of active power losses reduction in the power transmission lines under 1 kV and 6–10 kV of the systems of electric power supply of industrial enterprises with compensating installations mounted at the side of the customer. The capacitor installations conform to the applied voltage level and factor in dielectric losses in the capacitors. The voltage at the compensating device terminal changes from 0.95 to 1.05 of the capacitors nominal voltage. The study did not account for reactive power losses in the line, nor did it for its charge capacity, conditioned by relative shortness of the cable lines generally operating in the mains of industrial enterprises. For this reason, the quantities of reactive power being consumed and generated by the transmission line are negligible and do not significantly affect the reactive power flux. The researchers obtain functional relations that allow estimating the degree of power loss reduction in the transmission line factoring in its explicit initial data. They perform mathematical analysis of the obtained functional relations and study the function by means of derivatives. The function extremum points are found as well as the intervals of its increment and decrement. A graphical research of the obtained functional relation is performed. It is ascertained that reduction of the active power losses is contingent on the line and the capacitor-installation engineering factors, the electrical energy consumer reactive load value as well as the voltage applied to the capacitor installation. The functional relations presented in the article can be employed in scoping calculation necessary for decision making on the reactive power compensation in systems of the industrial facilities electric power supply. Their account will allow a more accurate estimate of technical and economic effect of the capacitor bank installation in the electrical mains under 1 kV and 6

  13. Bouncing Back from a Breakup: Attachment, Time Perspective, Mental Health, and Romantic Loss

    Science.gov (United States)

    Gilbert, Steven P.; Sifers, Sarah K.

    2011-01-01

    Coping with a romantic breakup is a normal developmental task of emerging adulthood. Because of their role in influencing interpersonal relationships and adjustment, attachment history and time perspectives may influence resilience to romantic loss. In an online survey of 1,404 university students ages 18-25 who reported experiencing recent…

  14. Natural hazard losses: A DOE (Department of Energy) perspective. Injury and property damage experience from natural phenomena hazards Department of Energy 1943-1989

    International Nuclear Information System (INIS)

    Hill, J.R.

    1989-01-01

    This presentation provides a perspective of DOE losses during the past 46 years even though loss data was not readily available for all DOE operations. As such this paper is considered preliminary and more work is needed to provide an informed view of all DOE losses. Review of the reported historical losses has provided an opportunity to create an awareness of the extent and location of a wide variety of natural phenomena hazards that have caused damage at most DOE sites. Some suggestions and observations to consider are: (1) mitigation strategies may achieve greatest reductions in wind damage; (2) most damage has occurred to conventional construction; (3) lightning damage review may provide insight for design standards change; (4) flood damage occurred where least expected. Through this awareness, the author hopes we are encouraged to provide our ideas and our professional skills for a Decade of Natural Hazard Reduction in the Department of Energy

  15. Parameter-free Network Sparsification and Data Reduction by Minimal Algorithmic Information Loss

    KAUST Repository

    Zenil, Hector

    2018-02-16

    The study of large and complex datasets, or big data, organized as networks has emerged as one of the central challenges in most areas of science and technology. Cellular and molecular networks in biology is one of the prime examples. Henceforth, a number of techniques for data dimensionality reduction, especially in the context of networks, have been developed. Yet, current techniques require a predefined metric upon which to minimize the data size. Here we introduce a family of parameter-free algorithms based on (algorithmic) information theory that are designed to minimize the loss of any (enumerable computable) property contributing to the object\\'s algorithmic content and thus important to preserve in a process of data dimension reduction when forcing the algorithm to delete first the least important features. Being independent of any particular criterion, they are universal in a fundamental mathematical sense. Using suboptimal approximations of efficient (polynomial) estimations we demonstrate how to preserve network properties outperforming other (leading) algorithms for network dimension reduction. Our method preserves all graph-theoretic indices measured, ranging from degree distribution, clustering-coefficient, edge betweenness, and degree and eigenvector centralities. We conclude and demonstrate numerically that our parameter-free, Minimal Information Loss Sparsification (MILS) method is robust, has the potential to maximize the preservation of all recursively enumerable features in data and networks, and achieves equal to significantly better results than other data reduction and network sparsification methods.

  16. AC Loss Reduction in Filamentized YBCO Coated Conductors with Virtual Transverse Cross-cuts

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yifei [ORNL; Duckworth, Robert C [ORNL; Ha, Tam T [ORNL; List III, Frederick Alyious [ORNL; Gouge, Michael J [ORNL; Chen, Y [SuperPower Incorporated, Schenectady, New York; X, Xiong, [SuperPower Incorporated, Schenectady, New York; Selvamanickam, V. [SuperPower Incorporated, Schenectady, New York

    2011-01-01

    While the performance of YBa{sub 2}Cu{sub 3}O{sub 7-x} (YBCO)-based coated conductors under dc currents has improved significantly in recent years, filamentization is being investigated as a technique to reduce ac loss so that the 2nd generation (2G) high temperature superconducting (HTS) wires can also be utilized in various ac power applications such as cables, transformers and fault current limiters. Experimental studies have shown that simply filamentizing the superconducting layer is not effective enough to reduce ac loss because of incomplete flux penetration in between the filaments as the length of the tape increases. To introduce flux penetration in between the filaments more uniformly and further reduce the ac loss, virtual transverse cross-cuts were made in superconducting filaments of the coated conductors fabricated using the metal organic chemical vapor deposition (MOCVD) method. The virtual transverse cross-cuts were formed by making cross-cuts (17 - 120 {micro}m wide) on the IBAD (ion beam assisted deposition)-MgO templates using laser scribing followed by depositing the superconducting layer ({approx} 0.6 {micro}m thick). AC losses were measured and compared for filamentized conductors with and without the cross-cuts under applied peak ac fields up to 100 mT. The results were analyzed to evaluate the efficacy of filament decoupling and the feasibility of using this method to achieve ac loss reduction.

  17. Determinants to dose reduction in EMCCR - in regulatory perspective

    International Nuclear Information System (INIS)

    Mohan, V.; Venkataraman, S.; Venkataraman, R.; Sajeev, B.S.

    2006-01-01

    Indian PHWRs had experienced three en masse coolant channel replacement campaigns, (EMCCR) first in RAPS-2, next in MAPS-2 and the last in MAPS-1. The campaign is already in full swing at NAPS-1. At MAPS, two EMCCR campaigns were done in a span of four years. The collective dose consumption in the MAPS-1 campaign was only about 25 % that of MAPS-2, a commendable achievement. Based on the experience of RAPS-2 and MAPS-2 campaigns, AERB - through several regulatory means- had given directives for reduction in collective dose in MAPS-1 campaign which was successfully implemented. This paper analyses and quantifies the key factors that contributed to collective dose reduction in MAPS-1 EMCCR. These factors could be put to use in the on going NAPS and forthcoming KAPS campaigns. (author)

  18. Emission reduction trading - a power marketer's perspective

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, M. (Powerex Inc., Vancouver, BC (Canada))

    1999-01-01

    The current situation , and the short-term and long-term outlook in emission reduction trading are reviewed from the point of view of a power marketer. The author's view is that while the concept of emission reduction credit (ERC) is easy enough to understand, i.e. a series of measures to reduce carbon dioxide production and enhance carbon sequestration, there is no standard definition, although there are a number of models under consideration. What is being sought is clear ownership and title, a clear understanding of what qualifies as a credit, credit for early action, commodity specifications and the ability to hedge. The author predicts that in the short-tem, industry will experiment with different types of transactions to gain experience and seek partners who are willing to share risk and development cost. In the longer-term, emission reduction credits will be bought and sold as commodities and traded, swapped or exchanged as part of a portfolio in bilateral trade transactions, and used in hedging against future liabilities.

  19. Emission reduction trading - a power marketer`s perspective

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, M. [Powerex Inc., Vancouver, BC (Canada)

    1999-10-01

    The current situation , and the short-term and long-term outlook in emission reduction trading are reviewed from the point of view of a power marketer. The author`s view is that while the concept of emission reduction credit (ERC) is easy enough to understand, i.e. a series of measures to reduce carbon dioxide production and enhance carbon sequestration, there is no standard definition, although there are a number of models under consideration. What is being sought is clear ownership and title, a clear understanding of what qualifies as a credit, credit for early action, commodity specifications and the ability to hedge. The author predicts that in the short-tem, industry will experiment with different types of transactions to gain experience and seek partners who are willing to share risk and development cost. In the longer-term, emission reduction credits will be bought and sold as commodities and traded, swapped or exchanged as part of a portfolio in bilateral trade transactions, and used in hedging against future liabilities.

  20. Indigenous knowledge for disaster risk reduction: An African perspective

    Directory of Open Access Journals (Sweden)

    Nnamdi G. Iloka

    2016-07-01

    Full Text Available Indigenous knowledge is valuable knowledge that has helped local communities all over the world survive for generations. This knowledge originates from the interaction between members of the community and the environment in which they live. Although much has been written about indigenous knowledge, its documentation in the area of disaster risk reduction and climate change in Africa has been very limited. The wealth of this knowledge has not been well-recognised in the disaster risk reduction field, as policy-makers still rely on mitigation strategies based on scientific knowledge. Colonialism and lack of proper documentation of indigenous knowledge are some of the contributing factors to this. Ignoring the importance of understanding adaptive strategies of the local people has led to failed projects. Understanding how local people in Africa have managed to survive and adapt for generations, before the arrival of Western education, may be the key to developing sustainable policies to mitigate future challenges. Literature used in this article, obtained from the books, papers and publications of various experts in the fields of disaster risk reduction, climate change, indigenous knowledge and adaptation, highlight the need for more interest to be shown in indigenous knowledge, especially in the developing country context. This would lead to better strategies which originate from the community level but would aim for overall sustainable development in Africa.

  1. A perspective on cost-effectiveness of greenhouse gas reduction solutions in water distribution systems

    International Nuclear Information System (INIS)

    Hendrickson, Thomas P; Horvath, Arpad

    2014-01-01

    Water distribution systems (WDSs) face great challenges as aging infrastructures require significant investments in rehabilitation, replacement, and expansion. Reducing environmental impacts as WDSs develop is essential for utility managers and policy makers. This study quantifies the existing greenhouse gas (GHG) footprint of common WDS elements using life-cycle assessment (LCA) while identifying the greatest opportunities for emission reduction. This study addresses oversights of the related literature, which fails to capture several WDS elements and to provide detailed life-cycle inventories. The life-cycle inventory results for a US case study utility reveal that 81% of GHGs are from pumping energy, where a large portion of these emissions are a result of distribution leaks, which account for 270 billion l of water losses daily in the United States. Pipe replacement scheduling is analyzed from an environmental perspective where, through incorporating leak impacts, a tool reveals that optimal replacement is no more than 20 years, which is in contrast to the US average of 200 years. Carbon abatement costs (CACs) are calculated for different leak reduction scenarios for the case utility that range from −$130 to $35 t −1  CO 2(eq) . Including life-cycle modeling in evaluating pipe materials identified polyvinyl chloride (PVC) and cement-lined ductile iron (DICL) as the Pareto efficient options, however; utilizing PVC presents human health risks. The model developed for the case utility is applied to California and Texas to determine the CACs of reducing leaks to 5% of distributed water. For California, annual GHG savings from reducing leaks alone (3.4 million tons of CO 2(eq) ) are found to exceed California Air Resources Board’s estimate for energy efficiency improvements in the state’s water infrastructure. (paper)

  2. Lung Volume Reduction in Pulmonary Emphysema from the Radiologist's Perspective.

    Science.gov (United States)

    Doellinger, F; Huebner, R H; Kuhnigk, J M; Poellinger, A

    2015-08-01

    Pulmonary emphysema causes decrease in lung function due to irreversible dilatation of intrapulmonary air spaces, which is linked to high morbidity and mortality. Lung volume reduction (LVR) is an invasive therapeutical option for pulmonary emphysema in order to improve ventilation mechanics. LVR can be carried out by lung resection surgery or different minimally invasive endoscopical procedures. All LVR-options require mandatory preinterventional evaluation to detect hyperinflated dysfunctional lung areas as target structures for treatment. Quantitative computed tomography can determine the volume percentage of emphysematous lung and its topographical distribution based on the lung's radiodensity. Modern techniques allow for lobebased quantification that facilitates treatment planning. Clinical tests still play the most important role in post-interventional therapy monitoring, but CT is crucial in the detection of postoperative complications and foreshadows the method's high potential in sophisticated experimental studies. Within the last ten years, LVR with endobronchial valves has become an extensively researched minimally-invasive treatment option. However, this therapy is considerably complicated by the frequent occurrence of functional interlobar shunts. The presence of "collateral ventilation" has to be ruled out prior to valve implantations, as the presence of these extraanatomical connections between different lobes may jeopardize the success of therapy. Recent experimental studies evaluated the automatic detection of incomplete lobar fissures from CT scans, because they are considered to be a predictor for the existence of shunts. To date, these methods are yet to show acceptable results. Today, surgical and various minimal invasive methods of lung volume reduction are in use. Radiological and nuclear medical examinations are helpful in the evaluation of an appropriate lung area. Imaging can detect periinterventional complications. Reduction of lung

  3. Ethics of tobacco harm reduction from a liberal perspective.

    Science.gov (United States)

    van der Eijk, Yvette

    2016-05-01

    Mixed evidence on the possible harms, benefits and usage patterns of electronic nicotine delivery systems (ENDS, or 'e-cigarettes'), has led to vigorous and ongoing debates on the issue. The ethical trade-off often represented is that, though smokers should be permitted access to ENDS as a less harmful alternative to smoking, this comes at the expense of non-smokers and children who may experiment with ENDS, become addicted to them, or experience health issues from long-term exposure to passive ENDS vapour. Lacking from many debates is a balanced analysis based on sound ethical reasoning, so this paper aims to examine the issue from a liberal perspective. More specifically, focus is on how ENDS policy can help to promote freedom in a broader sense, with 'freedom' considered as originating from having options and the necessary information and ability to autonomously choose between these options. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  4. The impact of rate of weight loss on body composition and compensatory mechanisms during weight reduction

    DEFF Research Database (Denmark)

    Coutinho, Sílvia Ribeiro; With, Emilie; Rehfeld, Jens F

    2018-01-01

    BACKGROUND & AIMS: Rapid weight loss (WL) has been associated with a larger loss of fat free mass and a disproportional reduction in resting metabolic rate (RMR), but the evidence is inconclusive. We aimed to evaluate the impact of WL rate on body composition and compensatory mechanisms activated...... with WL (reduced RMR, increased exercise efficiency (ExEff) and appetite), both during negative and neutral energy balance (EB). METHODS: Thirty-five participants with obesity were randomized to lose a similar weight rapidly (4 weeks) or gradually (8 weeks), and afterwards to maintain it (4 weeks). Body...... weight and composition, RMR, ExEff (10, 25 and 50 W), appetite feelings and appetite-regulating hormones (active ghrelin, cholecystokinin, total peptide YY (PYY), active glucagon-like peptide-1 and insulin), in fasting and every 30 min up to 2.5 h, were measured at baseline and after each phase. RESULTS...

  5. Network reconfiguration for loss reduction in electrical distribution system using genetic algorithm

    International Nuclear Information System (INIS)

    Adail, A.S.A.A.

    2012-01-01

    Distribution system is a critical links between the utility and the nuclear installation. During feeding electricity to that installation there are power losses. The quality of the network depends on the reduction of these losses. Distribution system which feeds the nuclear installation must have a higher quality power. For example, in Inshas site, electrical power is supplied to it from two incoming feeders (one from new abu-zabal substation and the other from old abu-zabal substation). Each feeder is designed to carry the full load, while the operator preferred to connect with a new abu-zabal substation, which has a good power quality. Bad power quality affects directly the nuclear reactor and has a negative impact on the installed sensitive equipment's of the operation. The thesis is Studying the electrical losses in a distribution system (causes and effected factors), feeder reconfiguration methods, and applying of genetic algorithm in an electric distribution power system. In the end, this study proposes an optimization technique based on genetic algorithms for distribution network reconfiguration to reduce the network losses to minimum. The proposed method is applied to IEEE test network; that contain 3 feeders and 16 nodes. The technique is applied through two groups, distribution have general loads, and nuclear loads. In the groups the technique applied to seven cases at normal operation state, system fault condition as well as different loads conditions. Simulated results are drawn to show the accuracy of the technique.

  6. A prospective study of short- and long-term cosmetic outcome after reduction mammaplasty from three different perspectives

    DEFF Research Database (Denmark)

    Breiting, Line Bro; Henriksen, Trine Foged; Kalialis, Louise Vennegaard

    2012-01-01

    Numerous studies have examined the outcome of reduction mammaplasty. This study evaluates the cosmetic outcome after reduction mammaplasty from the perspective of the patient, a ward surgeon, and a private practitioner in plastic surgery, and analyzes which factors influence it....

  7. Energy reduction in buildings in temperate and tropic regions utilizing a heat loss measuring device

    DEFF Research Database (Denmark)

    Sørensen, Lars Schiøtt

    2012-01-01

    There exist two ordinary ways to obtain global energy efficiency. One way is to make improvements on the energy production and supply side, and the other way is, in general, to reduce the consume of energy in the society. This paper has focus on the latter and especially the consume of energy...... for heating up, and cooling down our houses. There is a huge energy saving potential on this area reducing both the World climate problems and economy challenges as well. Heating of buildings in Denmark counts for approximately 40% of the entire national energy consume. Of this reason a reduction of heat...... losses from building envelopes are of great impor­tance in order to reach the Bologna CO2-emission reduction goals. Energy renovation of buildings is a topic of huge focus around the world these years. Not only expenses for heating in the tempered and arctic regions are of importance, but also expenses...

  8. Technology Roadmap. Energy Loss Reduction and Recovery in Industrial Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2004-11-01

    To help guide R&D decision-making and gain industry insights on the top opportunities for improved energy systems, ITP sponsored the Energy Loss Reduction and Recoveryin Energy Systems Roadmapping Workshopin April 2004 in Baltimore, Maryland. This Technology Roadmapis based largely on the results of the workshop and additional industrial energy studies supported by ITP and EERE. It summarizes industry feedback on the top opportunities for R&D investments in energy systems, and the potential for national impacts on energy use and the environment.

  9. Diet change and food loss reduction: What is their combined impact on global water use and scarcity?

    Science.gov (United States)

    Jalava, Mika; Guillaume, Joseph H. A.; Kummu, Matti; Porkka, Miina; Siebert, Stefan; Varis, Olli

    2016-03-01

    There is a pressing need to improve food security and reduce environmental impacts of agricultural production globally. Two of the proposed measures are diet change from animal-based to plant-based foodstuffs and reduction of food losses and waste. These two measures are linked, as diet change affects production and consumption of foodstuffs and consequently loss processes through their different water footprints and loss percentages. This paper takes this link into account for the first time and provides an assessment of the combined potential contribution of diet change and food loss reduction for reducing water footprints and water scarcity. We apply scenarios in which we change diets to follow basic dietary recommendations, limit animal-based protein intake to 25% of total protein intake, and halve food losses to study single and combined effects of diet change and loss reduction. Dietary recommendations alone would achieve 6% and 7% reductions of blue and green water consumption, respectively, while changing diets to contain less animal products would result in savings of 11% and 18%, respectively. Halving food loss would alone achieve 12% reductions for both blue and green water. Combining the measures would reduce water consumption by 23% and 28%, respectively, lowering water scarcity in areas with a population of over 600 million. At a global scale, effects of diet change and loss reduction were synergistic with loss reductions being more effective under changed diet. This demonstrates the importance of considering the link between diet change and loss reduction in assessments of food security and resource use.

  10. Architects' perspectives on construction waste reduction by design.

    Science.gov (United States)

    Osmani, M; Glass, J; Price, A D F

    2008-01-01

    The construction, demolition and excavation waste arising in England was estimated at 91 million tonnes in 2003. The current thinking on construction waste minimisation is heavily focussed on several issues relating to physical construction waste and recycling guides. Indeed, much had been published on ways to improve on-site waste management and recycling activities but very few attempts made to address the effect of design practices on waste generation. However, there is a consensus in the literature that the architect has a decisive role to play in helping to reduce waste by focussing on designing out waste. This paper examines previous studies on architects' approach towards construction waste minimisation; and by means of a postal questionnaire, investigates: the origins of waste; waste minimisation design practices in the UK; and responsibilities and barriers within the UK architectural profession. The findings reveal that waste management is not a priority in the design process. Additionally, the architects seemed to take the view that waste is mainly produced during site operations and rarely generated during the design stages; however, about one-third of construction waste could essentially arise from design decisions. Results also indicate that a number of constraints, namely: lack of interest from clients; attitudes towards waste minimisation; and training all act as disincentives to a proactive and sustainable implementation of waste reduction strategies during the design process.

  11. Architects' perspectives on construction waste reduction by design

    International Nuclear Information System (INIS)

    Osmani, M.; Glass, J.; Price, A.D.F.

    2008-01-01

    The construction, demolition and excavation waste arising in England was estimated at 91 million tonnes in 2003. The current thinking on construction waste minimisation is heavily focussed on several issues relating to physical construction waste and recycling guides. Indeed, much had been published on ways to improve on-site waste management and recycling activities but very few attempts made to address the effect of design practices on waste generation. However, there is a consensus in the literature that the architect has a decisive role to play in helping to reduce waste by focussing on designing out waste. This paper examines previous studies on architects' approach towards construction waste minimisation; and by means of a postal questionnaire, investigates: the origins of waste; waste minimisation design practices in the UK; and responsibilities and barriers within the UK architectural profession. The findings reveal that waste management is not a priority in the design process. Additionally, the architects seemed to take the view that waste is mainly produced during site operations and rarely generated during the design stages; however, about one-third of construction waste could essentially arise from design decisions. Results also indicate that a number of constraints, namely: lack of interest from clients; attitudes towards waste minimisation; and training all act as disincentives to a proactive and sustainable implementation of waste reduction strategies during the design process

  12. Drainage water management combined with cover crop enhances reduction of soil phosphorus loss.

    Science.gov (United States)

    Zhang, T Q; Tan, C S; Zheng, Z M; Welacky, T; Wang, Y T

    2017-05-15

    Integrating multiple practices for mitigation of phosphorus (P) loss from soils may enhance the reduction efficiency, but this has not been studied as much as individual ones. A four-year study was conducted to determine the effects of cover crop (CC) (CC vs. no CC, NCC) and drainage water management (DWM) (controlled drainage with sub-irrigation, CDS, vs. regular free tile drainage, RFD) and their interaction on P loss through both surface runoff (SR) and tile drainage (TD) water in a clay loam soil of the Lake Erie region. Cover crop reduced SR flow volume by 32% relative to NCC, regardless of DWM treatment. In contrast, CC increased TD flow volume by 57 and 9.4% with CDS and RFD, respectively, compared to the corresponding DWM treatment with NCC. The total (SR+TD) field water discharge volumes were comparable amongst all the treatments. Cover crop reduced flow-weighted mean (FWM) concentrations of particulate P (PP) by 26% and total P (TP) by 12% in SR, while it didn't affect the FWM dissolved reactive P (DRP) concentration, regardless of DWM treatments. Compared with RFD, CDS reduced FWM DRP concentration in TD water by 19%, while CC reduced FWM PP and TP concentrations in TD by 21 and 17%, respectively. Total (SR+TD) soil TP loss was the least with CDS-CC followed by RFD-CC, CDS-NCC, and RFD-NCC. Compared with RFD-NCC, currently popular practice in the region, total TP loss was reduced by 23% with CDS-CC. The CDS-CC system can be an effective practice to ultimately mitigate soil P loading to water resource. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Development and application of a decision support tool for reduction of product losses in the food-processing industry

    NARCIS (Netherlands)

    Akkerman, Renzo; van Donk, Dirk Pieter

    2008-01-01

    In food-processing industries, reduction of product losses is important for improving profitability and sustainability. This paper presents a decision support tool for analyzing the effects of planning decisions on the amount of product losses in the food-processing industry. We created a research

  14. Between harm reduction, loss and wellness: on the occupational hazards of work.

    Science.gov (United States)

    Shepard, Benjamin C

    2013-04-01

    Those working in the fields of harm reduction, healthcare, and human services must cope with a range of stresses, including post traumatic stress and vicarious trauma. Pain and loss are just a part of the job. So is dealing with premature death as a result of HIV, hypertension, and even overdose. Faced with a range of challenges, some workers in the field even turn to self-medication. For some, it is about pleasure; for others it is about alleviating suffering. In recent years, several leaders in the AIDS and harm reduction fields have died ahead of their time. Some stopped taking their medications; others overdosed. Rather than weakness or pathology, French sociologist Emile Durkheim saw self-destructive behavior as a byproduct of social disorganization and isolation, as a way of contending with a breakdown of social bonds and alienation. There are any number of reasons why such behavior becomes part of work for those involved with battling the dueling epidemics of Hepatitis C, HIV, and related concerns. Forms of stress related to this work include secondary trauma, compassion fatigue, organizational conflict, burnout, complications of direct services, and lack of funding. Faced with day-to- day struggles over poverty, punitive welfare systems, drug use, the war on drugs, high risk behavior, structural violence, and illness, many in the field are left to wonder how to strive for wellness when taking on so much pain. For some, self-injury and self-medication are ways of responding. Building on ethnographic methods, this reflective analysis considers the stories of those who have suffered, as well as a few of the ways those in the field cope with harm and pain. The work considers the moral questions we face when we see our friends and colleagues suffer. It asks how we as practitioners strive to create a culture of wellness and support in the fields of harm reduction, healthcare, and human services. Through a brief review of losses and literature thereof, the essay

  15. Comparative study of beam losses and heat loads reduction methods in MITICA beam source

    Energy Technology Data Exchange (ETDEWEB)

    Sartori, E., E-mail: emanuele.sartori@igi.cnr.it; Agostinetti, P.; Dal Bello, S.; Marcuzzi, D.; Serianni, G.; Veltri, P. [Consorzio RFX, Euratom-ENEA association, C.so Stati Uniti 4, 35127 Padova (Italy); Sonato, P. [Consorzio RFX, Euratom-ENEA association, C.so Stati Uniti 4, 35127 Padova (Italy); Dipartimento di Ingegneria Elettrica, Padova University, Via Gradenigo 6/a, 35131 Padova (Italy)

    2014-02-15

    In negative ion electrostatic accelerators a considerable fraction of extracted ions is lost by collision processes causing efficiency loss and heat deposition over the components. Stripping is proportional to the local density of gas, which is steadily injected in the plasma source; its pumping from the extraction and acceleration stages is a key functionality for the prototype of the ITER Neutral Beam Injector, and it can be simulated with the 3D code AVOCADO. Different geometric solutions were tested aiming at the reduction of the gas density. The parameter space considered is limited by constraints given by optics, aiming, voltage holding, beam uniformity, and mechanical feasibility. The guidelines of the optimization process are presented together with the proposed solutions and the results of numerical simulations.

  16. Analysis of risk reduction methods for interfacing system LOCAs [loss-of-coolant accidents] at PWRs

    International Nuclear Information System (INIS)

    Bozoki, G.; Kohut, P.; Fitzpatrick, R.

    1988-01-01

    The Reactor Safety Study (WASH-1400) predicted that Interfacing System Loss-of-Coolant Accidents (ISL) events were significant contributors to risk even though they were calculated to be relatively low frequency events. However, there are substantial uncertainties involved in determining the probability and consequences of the ISL sequences. For example, the assumed valve failure modes, common cause contributions and the location of the break/leak are all uncertain and can significantly influence the predicted risk from ISL events. In order to provide more realistic estimates for the core damage frequencies (CDFs) and a reduction in the magnitude of the uncertainties, a reexamination of ISL scenarios at PWRs has been performed by Brookhaven National Laboratory. The objective of this study was to investigate the vulnerability of pressurized water reactor designs to ISLs and identify any improvements that could significantly reduce the frequency/risk of these events

  17. Reduction of orthophosphates loss in agricultural soil by nano calcium sulfate.

    Science.gov (United States)

    Chen, Dong; Szostak, Paul; Wei, Zongsu; Xiao, Ruiyang

    2016-01-01

    Nutrient loss from soil, especially phosphorous (P) from farmlands to natural water bodies via surface runoff or infiltration, have caused significant eutrophication problems. This is because dissolved orthophosphates are usually the limiting nutrient for algal blooms. Currently, available techniques to control eutrophication are surprisingly scarce. Calcium sulfate or gypsum is a common soil amendment and has a strong complexation to orthophosphates. The results showed that calcium sulfate reduced the amount of water extractable P (WEP) through soil incubation tests, suggesting less P loss from farmlands. A greater decrease in WEP occurred with a greater dosage of calcium sulfate. Compared to conventional coarse calcium sulfate, nano calcium sulfate further reduced WEP by providing a much greater specific surface area, higher solubility, better contact with the fertilizer and the soil particles, and superior dispersibility. The enhancement of the nano calcium sulfate for WEP reduction is more apparent for a pellet- than a powdered- fertilizer. At the dosage of Ca/P weight ratio of 2.8, the WEP decreased by 31±5% with the nano calcium sulfate compared to 20±5% decrease with the coarse calcium sulfate when the pellet fertilizer was used. Computation of the chemical equilibrium speciation shows that calcium hydroxyapatite has the lowest solubility. However, other mineral phases such as hydroxydicalcium phosphate, dicalcium phosphate dihydrate, octacalcium phosphate, and tricalcium phosphate might form preceding to calcium hydroxyapatite. Since calcium sulfate is the major product of the flue gas desulfurization (FGD) process, this study demonstrates a potential beneficial reuse and reduction of the solid FGD waste. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Do hearing loss and cognitive function modulate benefit from different binaural noise-reduction settings?

    Science.gov (United States)

    Neher, Tobias; Grimm, Giso; Hohmann, Volker; Kollmeier, Birger

    2014-01-01

    Although previous research indicates that cognitive skills influence benefit from different types of hearing aid algorithms, comparatively little is known about the role of, and potential interaction with, hearing loss. This holds true especially for noise reduction (NR) processing. The purpose of the present study was thus to explore whether degree of hearing loss and cognitive function modulate benefit from different binaural NR settings based on measures of speech intelligibility, listening effort, and overall preference. Forty elderly listeners with symmetrical sensorineural hearing losses in the mild to severe range participated. They were stratified into four age-matched groups (with n = 10 per group) based on their pure-tone average hearing losses and their performance on a visual measure of working memory (WM) capacity. The algorithm under consideration was a binaural coherence-based NR scheme that suppressed reverberant signal components as well as diffuse background noise at mid to high frequencies. The strength of the applied processing was varied from inactive to strong, and testing was carried out across a range of fixed signal-to-noise ratios (SNRs). Potential benefit was assessed using a dual-task paradigm combining speech recognition with a visual reaction time (VRT) task indexing listening effort. Pairwise preference judgments were also collected. All measurements were made using headphone simulations of a frontal speech target in a busy cafeteria. Test-retest data were gathered for all outcome measures. Analysis of the test-retest data showed all data sets to be reliable. Analysis of the speech scores showed that, for all groups, speech recognition was unaffected by moderate NR processing, whereas strong NR processing reduced intelligibility by about 5%. Analysis of the VRT scores revealed a similar data pattern. That is, while moderate NR did not affect VRT performance, strong NR impaired the performance of all groups slightly. Analysis of the

  19. Report on feasibility study in fiscal 1999. Energy loss reduction project in Myanmar

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Discussions were given on reduction of greenhouse effect gas emission by improving the efficiency of electric power generation facilities and reducing the power transmission loss in Myanmar to link the project to the clean development mechanism. Shwedaung Power Station, Mann Power Station and the transmission system in Mandalay District were taken up as the object of the discussions. Profitability as a result of improving the thermal power generation facilities was calculated as the financial internal rate of return (FIRR) to discuss the feasibility of the implementation of the project. Since the single-shaft gas turbine currently in use has low efficiency, expansion or new installation of the new compound cycle power generation facilities would be most effective providing excellent thermal efficiency and power generation cost efficiency. The FIRR from improving the Shwedaung thermal power plant was calculated as 12.8%, and the Mann power plant as 9.4%, being regarded sufficiently worth for investment. The measures to reduce the transmission loss include introduction of higher voltage, setting new routes, increasing the conductor sizes, enhancing the power factor, and improving the facilities. The economic internal rate of return (EIRR) and the FIRR were calculated to discuss the project feasibility. In case of assuming the subjected analysis period to be ten years, the EIRR was estimated to be 20.41% (exceeding the social discount rate of 10%) and the FIRR to be 17.56% (exceeding the general loan interest of 15%), indicating the project realizable. (NEDO)

  20. An extended dual input dual output three level Z source inverter with improved switch loss reduction technique

    Directory of Open Access Journals (Sweden)

    N.B. Deshmukh

    2016-12-01

    Full Text Available Multilevel inverter (MLI is a proven technology used for industrial applications due to low output total harmonic distortion (THD, high power handling capability and low active device rating. Dual output inverter is a recent trend associated with inverter topologies for specialized applications. This paper deals with three phase three level dual input dual output inverter topology with minimum active device count. Reduction in switch count leads to reduction in losses and improves reliability. Both the input sources share power equally as neutral point current ripple is maintained low. For further reduction in switching losses at higher switching frequencies, the concept of “no switching zone” or discontinuous pulse width modulation (DPWM has been put forth recently. This paper proposes modification in the placement of “no switching zone” in order to optimize switching losses and output THD (output filtering requirements for low power factor load. This study also proposes novel graphical approach to analyze the loss reduction along with its effect on output THD. The sinusoidal PWM (SPWM is used which gives satisfactory switching loss reduction without complex calculations. Moreover, the proposed topology is generalized to provide dual output at higher voltage levels. It is seen that the components reduction phenomenon becomes more pronounced as number of levels goes on increasing. The proposed converter is simulated in MATLAB software environment and results are obtained.

  1. Nitrogen loss from anaerobic ammonium oxidation coupled to Iron(III) reduction in a riparian zone.

    Science.gov (United States)

    Ding, Bangjing; Li, Zhengkui; Qin, Yunbin

    2017-12-01

    Anaerobic ammonium oxidation coupled to iron(III) reduction (termed Feammox) is a recently discovered pathway of nitrogen cycling. However, little is known about the pathways of N transformation via Feammox process in riparian zones. In this study, evidence for Feammox in riparian zones with or without vegetation cover was demonstrated using isotope tracing technique and high-throughput sequencing technology. The results showed that Feammox could occur in riparian zones, and demonstrated that N 2 directly from Feammox was dominant Feammox pathway. The Feammox rates in vegetated soil samples was 0.32-0.37 mg N kg -1 d -1 , which is higher than that in un-vegetated soil samples (0.20 mg N kg -1 d -1 ). Moreover, the growth of vegetation led to a 4.99-6.41% increase in the abundance of iron reducing bacteria (Anaeromyxobacter, Pseudomonas and Geobacter) and iron reducing bacteria play an essential role in Feammox process. An estimated loss of 23.7-43.9 kg N ha -1 year -1 was associated with Feammox in the examined riparian zone. Overall, the co-occurrence of ammonium oxidation and iron reduction suggest that Feammox can play an essential role in the pathway of nitrogen removal in riparian zones. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Environmental Profile of the Swiss Supply Chain for French Fries: Effects of Food Loss Reduction, Loss Treatments and Process Modifications

    Directory of Open Access Journals (Sweden)

    Patrik Mouron

    2016-11-01

    Full Text Available The production of food is responsible for major environmental impacts. Bearing this in mind, it is even worse when food is lost rather than consumed. In Switzerland, 46% of all processing potatoes and 53% of all fresh potatoes are lost on their way from field to fork. Our study therefore compares the environmental impacts of losses of fresh potatoes with those of French fries. With the aid of a Life Cycle Assessment, we assessed the impact categories “demand for nonrenewable energy resources”, “global warming potential”, “human toxicity”, “terrestrial ecotoxicity” and “aquatic ecotoxicity”. Our results show that 1 kg of potatoes consumed as French fries causes 3–5 times more environmental impacts than the same quantity of fresh potatoes, but also that the proportion of impacts relating to losses is considerably lower for French fries (5%–10% vs. 23%–39%. The great majority of processing potato losses occur before the resource-intensive, emission-rich frying processes and therefore the environmental “backpack” carried by each lost potato is still relatively small. Nonetheless, appropriate loss treatment can substantially reduce the environmental impact of potato losses. In the case of French fries, the frying processes and frying oil are the main “hot spots” of environmental impacts, accounting for a considerably higher proportion of damage than potato losses; it is therefore also useful to look at these processes.

  3. Reductions in knee joint forces with weight loss are attenuated by gait adaptations in class III obesity.

    Science.gov (United States)

    DeVita, Paul; Rider, Patrick; Hortobágyi, Tibor

    2016-03-01

    A consensus exists that high knee joint forces are a precursor to knee osteoarthritis and weight loss reduces these forces. Because large weight loss also leads to increased step length and walking velocity, knee contact forces may be reduced less than predicted by the magnitude of weight loss. The purpose was to determine the effects of weight loss on knee muscle and joint loads during walking in Class III obese adults. We determined through motion capture, force platform measures and biomechanical modeling the effects of weight loss produced by gastric bypass surgery over one year on knee muscle and joint loads during walking at a standard, controlled velocity and at self-selected walking velocities. Weight loss equaling 412 N or 34% of initial body weight reduced maximum knee compressive force by 824 N or 67% of initial body weight when walking at the controlled velocity. These changes represent a 2:1 reduction in knee force relative to weight loss when walking velocity is constrained to the baseline value. However, behavioral adaptations including increased stride length and walking velocity in the self-selected velocity condition attenuated this effect by ∼50% leading to a 392 N or 32% initial body weight reduction in compressive force in the knee joint. Thus, unconstrained walking elicited approximately 1:1 ratio of reduction in knee force relative to weight loss and is more indicative of walking behavior than the standard velocity condition. In conclusion, massive weight loss produces dramatic reductions in knee forces during walking but when patients stride out and walk faster, these favorable reductions become substantially attenuated. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Hearing devices for children with unilateral hearing loss: Patient- and parent-reported perspectives.

    Science.gov (United States)

    Purcell, Patricia L; Jones-Goodrich, Rose; Wisneski, Meghan; Edwards, Todd C; Sie, Kathleen C Y

    2016-11-01

    Management of children with unilateral hearing loss is not standardized. The primary goal of this study was to elicit patient- and parent-reported perspectives regarding usage of hearing devices in pediatric UHL and to suggest a basic algorithmic approach to management. Our tertiary care center recruited families of youth ages 5-19 years with unilateral hearing loss from January 2014 through October 2015. Parents of all youths completed a 36-item survey, and some youth ages 11-19 years participated in hour-long interviews. We assessed patterns of hearing device usage among participants, and performed qualitative data analysis to understand factors considered by youths when deciding whether or not to use a hearing device. Survey information was collected for 50 patients. Distribution of hearing loss severity in affected ear was mild 14%, moderate 26%, severe 22%, and profound 38%. The majority of children had sensorineural hearing loss (57%), followed by mixed (32%), and then conductive (11%). 34 children (68%) had tried a hearing device; 20 continued to use the device. Retention rates were similar among children with different degrees of hearing loss: mild 66%, moderate 50%, severe 60%, profound 64%. Sixteen children tried a wireless contralateral routing of signal (CROS) device, and 15 tried a behind-the-ear (BTE) hearing aid. Retention rates for CROS and BTE devices were 69% and 47%, respectively. The most common reason for cessation of use was discomfort, followed by lack of benefit. A majority of children with unilateral hearing loss who tried a hearing device continued to use it, and retention rates were similar across all degrees of hearing loss. These findings suggest that personal hearing devices should be included in management protocols. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  5. AC loss performance of cable-in-conduit conductor. Influence of cable mechanical property on coupling loss reduction

    International Nuclear Information System (INIS)

    Matsui, Kunihiro; Koizumi, Norikiyo; Isono, Takaaki; Hamada, Kazuya; Nunoya, Yoshihiko

    2003-01-01

    The ITER Central Solenoid (CS) model coil, CS Insert and Nb 3 Al Insert were developed and tested from 2000 to 2002. The AC loss performances of these coils were investigated in various experiments. In addition, the AC losses of the CS and Nb 3 Al Insert conductors were measured using short CS and Nb 3 Al Insert conductors before the coil tests. The coupling time constants of these conductors were estimated to be 30 and 120 ms, respectively. On the other hand, the test results of the CS and Nb 3 Al Inserts show that the coupling currents induced in these conductors had multiple decay time constants. In fact, the existence of the coupling currents with long decay time constants, the order of which was in the thousands of seconds, was directly observed with hall sensors and voltage taps. Moreover, the AC loss test results show that electromagnetic force decreases coupling losses with exponential decay constants. This is because the weak sinter among the strands, which originated during heat treatment, was broken due to the electromagnetic force, and then the contact resistance among strands increased. It was found that this exponential decay constant was the function of a gap (i.e., a mechanical property of the cable) created between the cable and conduit due to electromagnetic force. The gap can be estimated by pressure drop, measured under the electromagnetic force. The pressure drop can easily be measured at an initial trial charge, and then it is possible to estimate the exponential decay constant before normal coil operation. Accordingly, it is possible to predict promptly how many times the trial operations are necessary to decrease the coupling losses to the designed value by measuring the coupling losses and the pressure drop during the initial coil operation trial. (author)

  6. Cognitive behavioral therapy to aid weight loss in obese patients: current perspectives.

    Science.gov (United States)

    Castelnuovo, Gianluca; Pietrabissa, Giada; Manzoni, Gian Mauro; Cattivelli, Roberto; Rossi, Alessandro; Novelli, Margherita; Varallo, Giorgia; Molinari, Enrico

    2017-01-01

    Obesity is a chronic condition associated with risk factors for many medical complications and comorbidities such as cardiovascular diseases, some types of cancer, osteoarthritis, hypertension, dyslipidemia, hypercholesterolemia, type-2 diabetes, obstructive sleep apnea syndrome, and different psychosocial issues and psychopathological disorders. Obesity is a highly complex, multifactorial disease: genetic, biological, psychological, behavioral, familial, social, cultural, and environmental factors can influence in different ways. Evidence-based strategies to improve weight loss, maintain a healthy weight, and reduce related comorbidities typically integrate different interventions: dietetic, nutritional, physical, behavioral, psychological, and if necessary, pharmacological and surgical ones. Such treatments are implemented in a multidisciplinary context with a clinical team composed of endocrinologists, nutritionists, dietitians, physiotherapists, psychiatrists, psychologists, and sometimes surgeons. Cognitive behavioral therapy (CBT) is traditionally recognized as the best established treatment for binge eating disorder and the most preferred intervention for obesity, and could be considered as the first-line treatment among psychological approaches, especially in a long-term perspective; however, it does not necessarily produce a successful weight loss. Traditional CBT for weight loss and other protocols, such as enhanced CBT, enhanced focused CBT, behavioral weight loss treatment, therapeutic education, acceptance and commitment therapy, and sequential binge, are discussed in this review. The issue of long-term weight management of obesity, the real challenge in outpatient settings and in lifestyle modification, is discussed taking into account the possible contribution of mHealth and the stepped-care approach in health care.

  7. Sesame improvement through mutation induction for reduction of seed loss at harvest (semi-shattering capsules)

    International Nuclear Information System (INIS)

    Maneekao, S.; Srikul, N.; Poo-Sri, B.; Kumphai, S.

    2001-01-01

    In 1994, the study of sesame improvement for reduction of seed loss by mutation was conducted at Ubonratchathani Field Crops Research Center (UBFCRC). There were two experiments carried out to improve sesame capsule for non-shattering characteristics using gamma rays and fast neutrons. The first experiment was performed to study the effect of irradiation doses on sesame when applied at doses varying from 200 to 750 Gy. Results of the experiments showed that all sesame lines had LD 50 levels between 300-750 Gy when irradiated with gamma rays, and 20-80 Gy with fast neutron. The second experiment was done to investigate the effect of irradiation on shattering types of sesame capsules. Three local varieties, Red Pitsanulok, Black Burirum and white Granuan were irradiated with 500 Gy of gamma rays. In the dry season 1997-98, 24 plants of M 7 generation (black- and red- seeded lines) and 8 plants of M 5 generation (white-seeded lines) were selected for yield evaluation with three local varieties. The results show 3 shatter resistant lines, PMUB 1, PMUB 19 (both with shatter resistance scale 537) and GMUB 7 (with scale 637) in 1997-98 (772 in 1997) gave 27% higher seed yield than the original variety; 2 black seeded mutant lines BMUB 21 and BMUB 23 of which seed colour slowly fades and 2 mutant lines (GMUB 1, GMUB 3) with a high degree of tolerance to powdery mildew. (author)

  8. Reduction of solids and nutrient loss from agricultural land by tailwater recovery systems

    Science.gov (United States)

    Omer, A.R.; Miranda, Leandro E.; Moore, M. T.; Krutz, L. J.; Prince Czarnecki, J. M.; Kröger, R.; Baker, B. H.; Hogue, J.; Allen, P. J.

    2018-01-01

    Best management practices are being implemented throughout the Lower Mississippi River Alluvial Valley with the aim of alleviating pressures placed on downstream aquatic systems by sediment and nutrient losses from agricultural land; however, research evaluating the performance of tailwater recovery (TWR) systems, an increasingly important practice, is limited. This study evaluated the ability of TWR systems to retain sediment and nutrients draining from agricultural landscapes. Composite flow-based samples were collected during flow events (precipitation or irrigation) over a two-year period in six TWR systems. Performance was evaluated by comparing concentrations and loads in water entering TWR systems (i.e., runoff or influent) from agricultural fields to water overflow exiting TWR systems (effluent). Tailwater recovery systems did not reduce concentrations of solids and nutrients, but did reduce loads of solids, phosphorus (P), and nitrogen (N) by 43%, 32%, and 44%, respectively. Annual mean load reductions were 1,142 kg solids, 0.7 kg of P, and 3.8 kg of N. Performance of TWR systems was influenced by effluent volume, system fullness, time since the previous event, and capacity of the TWR system. Mechanistically, TWR systems retain runoff on the agricultural landscape, thereby reducing the amount of sediment and nutrients entering downstream waterbodies. System performance can be improved through manipulation of influential parameters.

  9. Reduction of skin effect losses in double-level-T-gate structure

    Energy Technology Data Exchange (ETDEWEB)

    Mikulics, M., E-mail: m.mikulics@fz-juelich.de; Hardtdegen, H.; Arango, Y. C.; Adam, R.; Fox, A.; Grützmacher, D. [Peter Grünberg Institute (PGI-9), Forschungszentrum Jülich, D-52425 Jülich (Germany); Jülich-Aachen Research Alliance, JARA, Fundamentals of Future Information Technology, D-52425 Jülich (Germany); Gregušová, D.; Novák, J. [Institute of Electrical Engineering, Slovak Academy of Sciences, SK-84104 Bratislava (Slovakia); Stanček, S. [Department of Nuclear Physic and Technique, Slovak University of Technology, SK-81219 Bratislava (Slovakia); Kordoš, P. [Institute of Electronics and Photonics, Slovak University of Technology, SK-81219 Bratislava (Slovakia); Sofer, Z. [Department of Inorganic Chemistry, Institute of Chemical Technology, Technická 5, Prague 6 (Czech Republic); Juul, L.; Marso, M. [Faculté des Sciences, de la Technologie et de la Communication, Université du Luxembourg, L-1359 Luxembourg (Luxembourg)

    2014-12-08

    We developed a T-gate technology based on selective wet etching yielding 200 nm wide T-gate structures used for fabrication of High Electron Mobility Transistors (HEMT). Major advantages of our process are the use of only standard photolithographic process and the ability to generate T-gate stacks. A HEMT fabricated on AlGaN/GaN/sapphire with gate length L{sub g} = 200 nm and double-stacked T-gates exhibits 60 GHz cutoff frequency showing ten-fold improvement compared to 6 GHz for the same device with 2 μm gate length. HEMTs with a double-level-T-gate (DLTG) structure exhibit up to 35% improvement of f{sub max} value compared to a single T-gate device. This indicates a significant reduction of skin effect losses in DLTG structure compared to its standard T-gate counterpart. These results agree with the theoretical predictions.

  10. Reduction of Thermal Loss in HTS Windings by Using Magnetic Flux Deflection

    Science.gov (United States)

    Tsuzuki, K.; Miki, M.; Felder, B.; Koshiba, Y.; Izumi, M.; Umemoto, K.; Aizawa, K.; Yanamoto, T.

    Efforts on the generation of intensified magnetic flux have been made for the optimized shape of HTS winding applications. This contributes to the high efficiency of the rotating machines using HTS windings. Heat generation from the HTS windings requires to be suppressed as much as possible, when those coils are under operation with either direct or alternative currents. Presently, the reduction of such thermal loss generated by the applied currents on the HTS coils is reported with a magnetic flux deflection system. The HTS coils are fixed together with flattened magnetic materials to realize a kind of redirection of the flux pathway. Eventually, the magnetic flux density perpendicular to the tape surface (equivalent to the a-b plane) of the HTS tape materials is reduced to the proximity of the HTS coil. To verify the new geometry of the surroundings of the HTS coils with magnetic materials, a comparative study of the DC coil voltage was done for different applied currents in prototype field-pole coils of a ship propulsion motor.

  11. Independence, loss, and social identity: Perspectives on driving cessation and dementia.

    Science.gov (United States)

    Sanford, Sarah; Rapoport, Mark J; Tuokko, Holly; Crizzle, Alexander; Hatzifilalithis, Stephanie; Laberge, Sarah; Naglie, Gary

    2018-01-01

    The purpose of this study on driving cessation was to explore the process of coping, decision-making and adaptation through this major life transition. We sought to examine understandings of the emotional responses of drivers and ex-drivers with dementia from the perspective of healthcare providers and family caregivers of persons with dementia. Interviews and focus groups were conducted with several key informant groups: healthcare providers who work with patients with dementia and their families ( N = 10), representatives from organizations that provide services and support for persons with dementia ( N = 6), and family caregivers of drivers and former drivers with dementia ( N = 13). Data analysis involved inductive analytic techniques to generate descriptive and analytic themes from the data. The main themes from the analysis involve the: (1) Loss of independence and disruption to identity connected to emotional responses to driving cessation; (2) Experience of driving cessation as one loss within a series of losses related to dementia; (3) Importance of addressing emotional and identity-related effects in supportive responses to driving cessation; and (4) Support for maintained and adapted roles as a strategy to provide meaning and purpose in the context of driving cessation. Driving cessation can represent a significant disruption to identity, and is closely linked to losses, such as independence, within people's broader experiences of grief and loss associated with dementia. The findings suggest the need for supportive responses that address unique emotion and identity-related aspects of driving cessation for people with dementia and their family caregivers.

  12. The Brazilian policy for reduction of accidents and violence aligns with international perspectives?

    Directory of Open Access Journals (Sweden)

    Karen Namie Sakata

    2014-12-01

    Full Text Available The study analyzed The Brazilian Policy for Reduction of Morbidity and Mortality from Accidents and Violence, in the socio-political perspective. We used as a base the chapter “Violence: a global public health problem” from the World Report on Violence and Health. The analysis revealed convergent and divergent elements of the Brazilian Policy in comparison with the international perspectives. We verified that the Brazilian Policy tried to converge to the international policies, however: it emphasizes the health promotion actions, but are limited to the context and behavior of individuals and individual communities; the performance of health professionals is expected without providing more structural investments, as the improvement in work conditions, the increase of financial and material resources; there are few clear definitions of the government and economical sector responsibilities.

  13. Reduction of water losses in the water utilities and in industrial plants. Senkung der Wasserverluste in oeffentlichen Versorgungen und Industrieanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Bolte, O.G.; Hammerer, M.; Heide, G.F.; Heydenreich, M.; Hoch, W.; Holtschulte, H.; Lienhard, K.; Sewerin, P.

    1987-01-01

    Although municipal and rural supply structures have little changed in principle, the reduction of water losses has become a topical subject to be coped with. The paper deals with the causes and implications of water losses, the influx analysis, water loss analysis, influx analysis in the case of large-scale water supply systems, the pressure feeding method, the detection of leaks with the help of correlation analyses, the quantitave measurement of drinking water supplies and a method serving to detect least defects. In each case reference is made to the limitations of the respective methods and processes. With 95 figs..

  14. Experimental study on using a high-temperature superconducting inductor for power loss reduction in an active power filter

    International Nuclear Information System (INIS)

    Chao, C; To, H P; Grantham, C; Rahman, M F

    2006-01-01

    An active power filter improves the electric power quality through the compensation of harmonics in the power network. A current-source active power filter using a conventional copper inductor for its energy storage has a significant power loss. The loss in the copper inductor can be substantially reduced by using a high-temperature superconducting (HTS) inductor instead. Experiments have been conducted on a prototype current-source active power filter for studying the power loss reduction effect and harmonics compensation performance of the active power filter using a HTS inductor. Experimental results are analysed and discussed in this paper

  15. Phosphate dosing of mains water : novel approaches to water loss reduction through leakage detection and policy [abstract

    OpenAIRE

    Ascott, M.J.; Gooddy, D.C.; Lapworth, D.J.; Stuart, M.E.

    2016-01-01

    Detection and t racing of leakage in the environment are essential component s of water loss reduction strategies. Industry standard techniques for tracing leaks include analysis of chlorine and trihalomethane concentrations, but levels of these determinands can fall belo w detection limits due to their volatile nature 1 . Consequently additional tools to trace leakage in the environment are a useful step ...

  16. Future Time Perspective Impacts Gain-Related but Not Loss-Related Intertemporal Choice.

    Science.gov (United States)

    Li, Tian; Tan, Yuxin; Gong, Xianmin; Yin, Shufei; Qiu, Fangshu; Hu, Xue

    2018-01-01

    Future time perspective (FTP) modulates individuals' temporal orientation in selecting their motivations and goals, which widely influences their cognitions and behaviors. However, it remains unclear how FTP exactly affects intertemporal choice. To clarify the effect of FTP on intertemporal choice, 90 college students ( M age = 21.70, SD = 1.23) were randomly assigned to the limited FTP condition (16 males, 29 females) and the open-ended FTP condition (17 males, 28 females). In the limited FTP condition, participants were instructed to imagine their states of being 70 years old, whereas in the open-ended FTP condition, they were instructed to describe their current states. All participants then completed a series of intertemporal choice tasks, in which they chose from gain- and loss-related choices occurring at various time points. Results showed that the participants who received the future-imagining manipulation had more limited FTP compared with those who did not receive the manipulation, which confirmed the validity of the FTP manipulation. A 2 (FTP: limited vs. open-ended) × 2 (type of choice: gain vs. loss) repeated measures ANOVA on discount rate revealed a significant interaction between these two factors. The participants in the limited FTP condition had higher discount rates on gain-related choices but showed no difference on loss-related choices compared with the participants under the open-ended FTP condition. The results suggest that limited FTP could lower individuals' future orientation (i.e., willingness to delay an outcome) on gain-related, but not on loss-related, intertemporal decision-making.

  17. Financial Crisis from the Trust and Loss Aversion Perspective in Emerging Romanian Capital Market

    Directory of Open Access Journals (Sweden)

    Antoniade-Ciprian ALEXANDRU

    2011-07-01

    Full Text Available In this paper we synthesized a study of financial crisis from the trust and loss aversion perspective on a particular case, Romanian emerging capital market. In a relative recent study we stopped with our data series at the level of 2008, November, but in this paper we continue our research until 2009, December. In a world-wide financial crisis and a global financial depreciation of stocks the emergent markets are much more affected that the lack of money and investors aversion. We study, based on efficient market theory, the evolution of portfolio structure in balanced funds. We are interesting to make an evaluation of present sentiment of investing money in capital markets and especially in stocks. Also, is necessary to determine which are the most important problems in this situation and seek an adequate stimulus for future development of direct investment.

  18. Economic Impact of Hearing Loss and Reduction of Noise-Induced Hearing Loss in the United States.

    Science.gov (United States)

    Neitzel, Richard L; Swinburn, Tracy K; Hammer, Monica S; Eisenberg, Daniel

    2017-01-01

    Hearing loss (HL) is pervasive and debilitating, and noise-induced HL is preventable by reducing environmental noise. Lack of economic analyses of HL impacts means that prevention and treatment remain a low priority for public health and environmental investment. This article estimates the costs of HL on productivity by building on established estimates for HL prevalence and wage and employment differentials between those with and without HL. We estimate that HL affects more than 13% of the working population. Not all HL can be prevented or treated, but if the 20% of HL resulting from excessive noise exposure were prevented, the economic benefit would be substantial-we estimate a range of $58 billion to $152 billion annually, with a core estimate of $123 billion. We believe this is a conservative estimate, because consideration of additional costs of HL, including health care and special education, would likely further increase the benefits associated with HL prevention. HL is costly and warrants additional emphasis in public and environmental health programs. This study represents an important first step in valuing HL prevention-in particular, prevention of noise-induced HL-where new policies and technologies appear promising.

  19. Prothrombin complex concentrate in the reduction of blood loss during orthotopic liver transplantation: PROTON-trial

    NARCIS (Netherlands)

    F. Arshad (Freeha); B. Ickx (Brigitte); R.T. van Beem (Rachel); W.G. Polak (Wojciech); F. Grüne (Frank); F. Nevens (Frederik); M. Ilmakunnas (Minna); A.M. Koivusalo (Anna-Maria); H. Isoniemi (Helena); P.F.W. Strengers; H.J.M. Groen (Henk); H.G.D. Hendriks (Herman); T. Lisman (Ton); J. Pirenne (Jacques); R.J. Porte (Robert)

    2013-01-01

    textabstractBackground: In patients with cirrhosis, the synthesis of coagulation factors can fall short, reflected by a prolonged prothrombin time. Although anticoagulants factors are decreased as well, blood loss during orthotopic liver transplantation can still be excessive. Blood loss during

  20. Prothrombin complex concentrate in the reduction of blood loss during orthotopic liver transplantation : PROTON-trial

    NARCIS (Netherlands)

    Arshad, Freeha; Ickx, Brigitte; van Beem, Rachel T.; Polak, Wojciech; Grune, Frank; Nevens, Frederik; Ilmakunnas, Minna; Koivusalo, Anna-Maria; Isoniemi, Helena; Strengers, Paul F. W.; Groen, Henk; Hendriks, Herman G. D.; Lisman, Ton; Pirenne, Jacques; Porte, Robert J.

    2013-01-01

    Background: In patients with cirrhosis, the synthesis of coagulation factors can fall short, reflected by a prolonged prothrombin time. Although anticoagulants factors are decreased as well, blood loss during orthotopic liver transplantation can still be excessive. Blood loss during orthotopic liver

  1. Reduction of core loss in non-oriented (NO) electrical steel by electroless-plated magnetic coating

    International Nuclear Information System (INIS)

    Chivavibul, Pornthep; Enoki, Manabu; Konda, Shigeru; Inada, Yasushi; Tomizawa, Tamotsu; Toda, Akira

    2011-01-01

    An important issue in development of electrical steels for core-laminated products is to reduce core loss to improve energy conversion efficiency. This is usually obtained by tailoring the composition, microstructure, and texture of electrical steels themselves. A new technique to reduce core loss in electrical steel has been investigated. This technique involves electroless plating of magnetic thin coating onto the surface of electrical steel. The material system was electroless Ni-Co-P coatings with different thicknesses (1, 5, and 10 μm) deposited onto the surface of commercially available Fe-3% Si electrical steel. Characterization of deposited Ni-Co-P coating was carried out using X-ray diffraction (XRD), scanning electron microscope (SEM), and energy dispersive X-ray (EDX) spectrometer. The deposited Ni-Co-P coatings were amorphous and composed of 56-59% Ni, 32-35% Co, and 8-10% P by mass. The effect of coatings on core loss of the electrical steel was determined using single sheet test. A core loss reduction of 4% maximum was achieved with the Ni-Co-P coating of 1 μm thickness at 400 Hz and 0.3 T. - Research Highlights: → New approach to reduce core loss of electrical steel by magnetic coating. → Ni-Co-P coating influences core loss of NO electrical steel. → Core loss increases in RD direction but reduces in TD direction.

  2. Leakage Detection and Estimation Algorithm for Loss Reduction in Water Piping Networks

    OpenAIRE

    Kazeem B. Adedeji; Yskandar Hamam; Bolanle T. Abe; Adnan M. Abu-Mahfouz

    2017-01-01

    Water loss through leaking pipes constitutes a major challenge to the operational service of water utilities. In recent years, increasing concern about the financial loss and environmental pollution caused by leaking pipes has been driving the development of efficient algorithms for detecting leakage in water piping networks. Water distribution networks (WDNs) are disperse in nature with numerous number of nodes and branches. Consequently, identifying the segment(s) of the network and the exa...

  3. Cognitive behavioral therapy to aid weight loss in obese patients: current perspectives

    Directory of Open Access Journals (Sweden)

    Castelnuovo G

    2017-06-01

    Full Text Available Gianluca Castelnuovo,1,2 Giada Pietrabissa,1,2 Gian Mauro Manzoni,1,3 Roberto Cattivelli,1,2 Alessandro Rossi,1 Margherita Novelli,1 Giorgia Varallo,1 Enrico Molinari1,2 1Psychology Research Laboratory, Istituto Auxologico Italiano IRCCS, San Giuseppe Hospital, Verbania, 2Department of Psychology, Catholic University of Milan, Milan, 3Faculty of Psychology, eCampus University, Novedrate, Italy Abstract: Obesity is a chronic condition associated with risk factors for many medical ­complications and comorbidities such as cardiovascular diseases, some types of cancer, osteoarthritis, hypertension, dyslipidemia, hypercholesterolemia, type-2 diabetes, obstructive sleep apnea syndrome, and different psychosocial issues and psychopathological disorders. Obesity is a highly complex, multifactorial disease: genetic, biological, psychological, behavioral, familial, social, cultural, and environmental factors can influence in different ways. Evidence-based strategies to improve weight loss, maintain a healthy weight, and reduce related comorbidities typically integrate different interventions: dietetic, nutritional, physical, behavioral, psychological, and if necessary, pharmacological and surgical ones. Such treatments are implemented in a multidisciplinary context with a clinical team composed of endocrinologists, nutritionists, dietitians, physiotherapists, psychiatrists, psychologists, and sometimes surgeons. Cognitive behavioral therapy (CBT is traditionally recognized as the best established treatment for binge eating disorder and the most preferred intervention for obesity, and could be considered as the first-line treatment among psychological approaches, especially in a long-term perspective; however, it does not necessarily produce a successful weight loss. Traditional CBT for weight loss and other protocols, such as enhanced CBT, enhanced focused CBT, behavioral weight loss treatment, therapeutic education, acceptance and commitment therapy

  4. Loss reduction in axial-flow compressors through low-speed model testing

    Science.gov (United States)

    Wisler, D. C.

    1984-01-01

    A systematic procedure for reducing losses in axial-flow compressors is presented. In this procedure, a large, low-speed, aerodynamic model of a high-speed core compressor is designed and fabricated based on aerodynamic similarity principles. This model is then tested at low speed where high-loss regions associated with three-dimensional endwall boundary layers flow separation, leakage, and secondary flows can be located, detailed measurements made, and loss mechanisms determined with much greater accuracy and much lower cost and risk than is possible in small, high-speed compressors. Design modifications are made by using custom-tailored airfoils and vector diagrams, airfoil endbends, and modified wall geometries in the high-loss regions. The design improvements resulting in reduced loss or increased stall margin are then scaled to high speed. This paper describes the procedure and presents experimental results to show that in some cases endwall loss has been reduced by as much as 10 percent, flow separation has been reduced or eliminated, and stall margin has been substantially improved by using these techniques.

  5. Radiant heat loss, an unexploited path for heat stress reduction in shaded cattle.

    Science.gov (United States)

    Berman, A; Horovitz, T

    2012-06-01

    Reducing thermal radiation on shaded animals reduces heat stress independently of other means of stress relief. Radiant heat exchange was estimated as a function of climate, shade structure, and animal density. Body surface portion exposed to radiant sources in shaded environments was determined by geometrical relations to determine angles of view of radiation sources (roof underside, sky, sun-exposed ground, shaded ground) on the animal's surface. The relative representation of environment radiation sources on the body surface was determined. Animal thermal radiation balance was derived from radiant heat gained from radiation sources (including surrounding animals) and that lost from the animal surface. The animal environment was assumed to have different shade dimensions and temperatures. These were summed to the radiant heat balance of the cow. The data formed served to estimate the effect of changes in intensity of radiation sources, roof and shaded surface dimensions, and animal density on radiant heat balance (Rbal) of cattle. Roof height effect was expressed by effect of roof temperature on Rbal. Roof underside temperature (35 to 75°C) effect on Rbal was reduced by roof height. If roof height were 4m, an increase in its underside temperature from 35 to 75°C would increase mean Rbal from -63 to -2 W·m⁻², whereas if roof height were 10 m, Rbal would only increase from -99 to -88 W·m⁻². A hot ground temperature increase from 35 to 65°C reduced mean Rbal heat loss from -45 to 3 W·m⁻². Increasing the surface of the shaded area had only a minor effect on Rbal and on the effect of hot ground on Rbal. Increasing shade roof height reduced the effect of roof temperature on Rbal to minor levels when height was > 8m. Increasing the roof height from 4 to 10 m decreased Rbal from -32 to -94 W·m⁻². Increasing indirect radiation from 100 to 500 W·m⁻² was associated with an increase in Rbal from -135 to +23 W·m⁻². Their combined effects were lower

  6. Production Time Loss Reduction in Sauce Production Line by Lean Six Sigma Approach

    Science.gov (United States)

    Ritprasertsri, Thitima; Chutima, Parames

    2017-06-01

    In all industries, time losses, which are incurred in processing are very important. As a result, losses are incurred in productivity and cost. This research aimed to reduce lost time that occurs in sauce production line by using the lean six sigma approach. The main objective was to reduce the time for heating sauce which causes a lot of time lost in the production line which affects productivity. The methodology was comprised of the five-phase improvement model of Six Sigma. This approach begins with defining phase, measuring phase, analysing phase, improving phase and controlling phase. Cause-and-effect matrix and failure mode and effect analysis (FMEA) were adopted to screen the factors which affect production time loss. The results showed that the percentage of lost time from heating sauce reduced by 47.76%. This increased productivity to meet the plan.

  7. ROLE OF 400 MCG INTRAOPERATIVE SUBLINGUAL MISOPROSTOL FOR REDUCTION OF CAESAREAN BLOOD LOSS

    Directory of Open Access Journals (Sweden)

    Lalmohan Nayak

    2017-02-01

    Full Text Available BACKGROUND Lower segment caesarean section is a common surgical procedure. Postpartum haemorrhage incidence after LSCS is 4%. Misoprostol is a prostaglandin E1 analogue with good uterotonic properties, easy availability, low cost, thermostability, long shelf life, easy administration and few adverse effects at therapeutic dose. It is readily absorbed by oral, sublingual, buccal, vaginal or rectal route. Sublingual route attains quickest concentration. Dose of 400 mcg was chosen in this study to minimise adverse effects with optimal therapeutic benefit. The aim of the study is to determine the efficacy of sublingual misoprostol in reducing caesarean blood loss. MATERIALS AND METHODS It is a prospective experimental study done in VSSIMSAR, Burla. Women undergoing LSCS were randomly assigned to study and control groups of equal strength of 100 each. In all cases, preoperative Hb%, haematocrit, pulse, BP was noted. Study group were given 400 mcg misoprostol at the time of cord clamping. In control group, nothing was given. In all patients, active management of third stage of labour was done by using oxytocin 10 IU (IV along with uterine massage. Blood loss soaked by tetra was calculated using formula, blood loss = wet weight-dry weight/1.05 (1.05 is constant. Amount of blood loss, postoperative Hb%, haematocrit, pulse rate, BP was noted in both groups and compared. BP and pulse were noted after 1 hour and Hb%, haematocrit were noted after 24 hours. RESULTS Study group showed significant decrease in total blood loss (around 117.9 mL as compared to control group. There was significant decrease in the postoperative fall in Hb in the study group as compared to control, the mean difference being 0.631 gm%. Study group also showed decrease in postoperative fall in haematocrit as compared to control, the mean difference being 0.055. CONCLUSION Misoprostol significantly reduced caesarean blood loss and doesn’t affect foetal outcome without significant

  8. Speed and Torque Control Strategies for Loss Reduction of Vertical Axis Wind Turbines

    Science.gov (United States)

    Argent, Michael; McDonald, Alasdair; Leithead, Bill; Giles, Alexander

    2016-09-01

    This paper builds on the work into modelling the generator losses for Vertical Axis Wind Turbines from their intrinsic torque cycling to investigate the effects of aerodynamic inefficiencies caused by the varying rotational speed resulting from different torque control strategies to the cyclic torque. This is achieved by modelling the wake that builds up from the rotation of the VAWT rotor to investigate how the wake responds to a changing rotor speed and how this in turn affects the torque produced by the blades as well as the corresponding change in generator losses and any changes to the energy extracted by the wind turbine rotor.

  9. Reduction of heat losses from greenhouses by means of internal blinds with low thermal emissivity

    NARCIS (Netherlands)

    Meijer, J.

    1980-01-01

    Heat losses in greenhouses may be substantially reduced by the use of heat reflecting blinds. Quantitative results are obtained solving a mathematical heat flow model by numerical methods. Special attention has been given to the emissivity and transmittance of the screen and the ventilation through

  10. The beneficial effect of Batroxobin on blood loss reduction in spinal fusion surgery

    DEFF Research Database (Denmark)

    Hu, Hui-Min; Chen, Li; Frary, Charles Edward

    2015-01-01

    Objective Our objective was to evaluate the efficacy and safety of Batroxobin on blood loss during spinal operations. Methods After obtaining approval from the ethics committee at the hospital along with informed written consent, we performed a double-blind, randomized, placebo-controlled study w...

  11. Real-time dynamic hydraulic model for potable water loss reduction

    CSIR Research Space (South Africa)

    Abu-Mahfouz, Adnan M

    2016-08-01

    Full Text Available South Africa is a water scarce country with limited water resources and steadily growing water demand. Unacceptably high water losses and non-revenue water threaten our water resource security as well as the financial viability of municipal water...

  12. Significant reduction in blood loss in patients undergoing minimal extracorporeal circulation

    NARCIS (Netherlands)

    Gerritsen, W. B.; van Boven, W. J.; Smelt, M.; Morshuis, W. J.; van Dongen, H. P.; Haas, F. J.; Aarts, L. P.

    2006-01-01

    Several recent studies have shown differences in blood loss and allogeneic transfusion requirements between on-pump and off-pump coronary artery bypass grafting (CABG). Recently a new concept, the mini-extracorporeal circulation, was introduced to minimize the side effects of extracorporeal

  13. Effects of weight loss and insulin reduction on arterial stiffness in the SAVE trial

    Directory of Open Access Journals (Sweden)

    Hughes Timothy M

    2012-09-01

    Full Text Available Abstract Background Chronic arterial stiffness contributes to the negative health effects of obesity and insulin resistance, which include hypertension, stroke, and increased cardiovascular and all-cause mortality. Weight loss and improved insulin sensitivity are individually associated with improved central arterial stiffness; however, their combined effects on arterial stiffness are poorly understood. The purpose of this study was to determine how insulin levels modify the improvements in arterial stiffness seen with weight loss in overweight and obese young adults. Methods To assess the effects of weight loss and decreased fasting insulin on vascular stiffness, we studied 339 participants in the Slow the Adverse Effects of Vascular Aging (SAVE trial. At study entry, the participants were aged 20–45, normotensive, non-diabetic, and had a body-mass index of 25–39.9 kg/m2. Measures of pulse wave velocity (PWV in the central (carotid-femoral (cfPWV, peripheral (femoral-ankle (faPWV, and mixed (brachial-ankle (baPWV vascular beds were collected at baseline and 6 months. The effects of 6-month change in weight and insulin on measures of PWV were estimated using multivariate regression. Results After adjustment for baseline risk factors and change in systolic blood pressure, 6-month weight loss and 6-month change in fasting insulin independently predicted improvement in baPWV but not faPWV or cfPWV. There was a significant interaction between 6-month weight change and change in fasting insulin when predicting changes in baPWV (p baPWV. Conclusions Young adults with excess weight who both lower their insulin levels and lose weight see the greatest improvement in vascular stiffness. This improvement in vascular stiffness with weight loss and insulin declines may occur throughout the vasculature and may not be limited to individual vascular beds. Trial registration NCT00366990

  14. Economic Performance and Emission Reduction of Supply Chains in Different Power Structures: Perspective of Sustainable Investment

    Directory of Open Access Journals (Sweden)

    Xiutian Shi

    2018-04-01

    Full Text Available Environmental issues have increasingly received attention in both industry and academia. Many firms have started to make sustainable investments, such as adopting the pollution-abatement technologies, to reduce carbon emissions. To investigate the impacts of the sustainable investment on firms’ profit and emission reduction, we consider supply chains with uncertain demand in different power structures. Specifically, we examine the sustainable investment problem in three supply chain power structures, i.e., manufacturer Stackelberg (MS power structure, vertical Nash (VN power structure and retailer Stackelberg (RS power structure. We first derive the optimal decisions for both the retailer and manufacturer in each power structure. Then, by comparing the results in the three power structures, we find that the manufacturer gets benefits from making the sustainable investment, especially in unequal power structures. When the average market size is large (small enough, both of the supply chain members obtain more profits in the MS (RS power structure. From an environmental perspective, we find that the emission reduction is more significant in sequential games (i.e., MS and RS power structures than that in a simultaneous game (i.e., VN power structure. In addition, we conduct some numerical studies and discuss more managerial insights in the paper.

  15. Reduction in soil loss from erosion-susceptible soils amended with humic substances from oxidized coal

    International Nuclear Information System (INIS)

    Piccolo, A.; Pietramellara, G.; Mbagwu, J.S.C.

    1997-01-01

    Soils that pose high risk of erosion require amendment with either natural or synthetic soil conditioners to reduce soil loss hazards. The objective of this study was to evaluate the potential of using coal-derived humic substances (as soil conditioners) to reduce runoff erosion on erosion-susceptible soils. Surface samples of severely degraded soils from Principina in Tuscany and Bovolone in Venice in Italy were used to assess the effects of five rates (0, 0.05, 0.01, 0.50 and 1.00 g/kg) of humic acids (HA) on soil loss and other hydrological parameters. The results showed that amending erosion-susceptible soils with low rates of coal-derived humic substances is a potentially effective soil management practice for reducing erosion rates

  16. Prediction of hydrological reduction factor and initial loss in urban surface runoff from small ungauged catchments

    DEFF Research Database (Denmark)

    Arnbjerg-Nielsen, K.; Harremoës, P.

    1996-01-01

    An advanced runoff model is compared to a simple one employing only a runoff coefficient and a regression parameter allowing for initial loss. The present study shows that the more detailed description of the runoff processes cannot be justified due to the uncertainty from using only one gauge...... in the evaluation of the yearly discharges. In the case of extreme events, the uncertainty of the predicted runoff of the single event should also be taken into account....

  17. Reduction of aspirin-induced fecal blood loss with low-dose misoprostol tablets in man

    International Nuclear Information System (INIS)

    Cohen, M.M.; Clark, L.; Armstrong, L.; D'Souza, J.

    1985-01-01

    Misoprostol (SC-29333), a synthetic prostaglandin E1 methyl ester analog, was given simultaneously with acetylsalicylic acid in a double-blind, placebo-controlled randomized prospective study of 32 healthy human male subjects. Fecal blood loss was measured for eight days using the 51 Cr-labeled red blood cell technique. Aspirin (650 mg qid) and misoprostol (25 micrograms qid) or placebo were given during days 3, 4, and 5. There was a significant (P less than 0.05) increase in median blood loss (modified Friedman test) from 0.81 to 6.05 ml/day in the aspirin with placebo group (N = 16). Median blood loss was increased (from 0.75 to 3.75 ml/day) in the aspirin with misoprostol group (N = 16), but this was significantly less (Mann-Whitney U test, P less than 0.01) than the placebo group. Mean serum salicylate concentrations in the placebo and misoprostol groups were similar (7.8 and 6.8 micrograms/ml, respectively). There were no significant changes in laboratory values in any of the subjects studied, nor were any major side-effects encountered. This study demonstrates that oral misoprostol reduces aspirin-induced gastrointestinal bleeding even when administered simultaneously and at a dose level below its threshold for significant acid inhibition. This indicates a potential role for misoprostol in the prevention of gastric mucosal damage in selected patients

  18. Leakage Detection and Estimation Algorithm for Loss Reduction in Water Piping Networks

    Directory of Open Access Journals (Sweden)

    Kazeem B. Adedeji

    2017-10-01

    Full Text Available Water loss through leaking pipes constitutes a major challenge to the operational service of water utilities. In recent years, increasing concern about the financial loss and environmental pollution caused by leaking pipes has been driving the development of efficient algorithms for detecting leakage in water piping networks. Water distribution networks (WDNs are disperse in nature with numerous number of nodes and branches. Consequently, identifying the segment(s of the network and the exact leaking pipelines connected to this segment(s where higher background leakage outflow occurs is a challenging task. Background leakage concerns the outflow from small cracks or deteriorated joints. In addition, because they are diffuse flow, they are not characterised by quick pressure drop and are not detectable by measuring instruments. Consequently, they go unreported for a long period of time posing a threat to water loss volume. Most of the existing research focuses on the detection and localisation of burst type leakages which are characterised by a sudden pressure drop. In this work, an algorithm for detecting and estimating background leakage in water distribution networks is presented. The algorithm integrates a leakage model into a classical WDN hydraulic model for solving the network leakage flows. The applicability of the developed algorithm is demonstrated on two different water networks. The results of the tested networks are discussed and the solutions obtained show the benefits of the proposed algorithm. A noteworthy evidence is that the algorithm permits the detection of critical segments or pipes of the network experiencing higher leakage outflow and indicates the probable pipes of the network where pressure control can be performed. However, the possible position of pressure control elements along such critical pipes will be addressed in future work.

  19. Reduction of the ionization loss distribution width of several simultaneous relativistic particles traversing a scintillation counter

    CERN Document Server

    Aderholz, M; Matthewson, R; Lehraus, I no 1; Matthewson, R no 1; Aderholz, M no 1

    1975-01-01

    A Poisson distribution of number of electrons at the input stages of a photomultiplier has been folded into a Landau-Symon distribution of ionization losses in a plastic scintillator and a distribution of the smallest value out of n detectors was derived analytically for m simultaneous particles. A group of four identical scintillation counters was constructed and the smallest of the four output pulses was used for selective triggering of the bubble chamber flash with the greater precision engendered by the considerably reduced distribution width. (22 refs).

  20. Alternating current loss reduction for rectangular busbars by covering their edges with low permeable magnetic caps

    Energy Technology Data Exchange (ETDEWEB)

    Sasada, Ichiro, E-mail: sasada@ence.kyushu-u.ac.jp [Applied Science for Electronics and Materials, Kyushu University, Kasuga (Japan)

    2014-05-07

    A method to reduce ac conductive losses in a thin rectangular busbar made of copper is presented. The method is based on a technique, which makes the distribution of the ac current in the cross section of a busbar flatter. Edges of a thin busbar are covered with low permeability magnetic thin layers as caps. The magnetic cap makes the impedance experienced by the current flowing near the edge comparatively larger so that currents cannot get crowded near the edges of a busbar. This method is numerically verified.

  1. Reduction of coupling loss to photonic crystal fibers by controlled hole collapse: A numerical study

    DEFF Research Database (Denmark)

    Lægsgaard, Jesper; Bjarklev, Anders Overgaard

    2004-01-01

    The mode profile evolution of small-core photonic crystal fibers (PCFs) during a gradual collapse of the cladding airholes is investigated. The mode overlap with standard step-index fibers having a small index contrast is calculated, and it is found that overlaps around 90% can be achieved in all...... cases studied, with the proper degree of hole collapse. Thus, hole collapse induced by, e.g. laser irradiation could prove an efficient and practical way of reducing splice losses when coupling small-core PCFs to other fiber types....

  2. An evaluation of the Davis-Besse loss of feedwater event (June 1985) from an accident management perspective

    International Nuclear Information System (INIS)

    Di Salvo, R.; Leonard, M.T.; Wreathall, J.

    1986-01-01

    An accident management perspective is used to analyze events associated with a total loss-of-feedwater at the Davis-Besse nuclear power plant in June 1985. The relationships of accident management to the closely associated concepts of risk management and emergency management are delineated. The analysis shows that the principal contributors to the event's occurrence were shortcomings in risk management. Successful performance by the operators in accident management was principally responsible for terminating the event without consequence to public health

  3. Slow extraction at the SPS: extraction efficiency and loss reduction studies

    CERN Document Server

    Fraser, M A; Cavoto, G; Galluccio, F; Gilardoni, S; Goddard, B; Iacoangeli, F; Kain, V; Mirarchi, D; Montesano, S; Murtas, F; Petrucci, S; Redaelli, S; Roncarolo, F; Rossi, R; Scandale, W; Stoel, L S; Velott, F M

    2017-01-01

    Elevated activation levels in LSS2 were first reported dur-ing an intervention on the SPS extraction septum (ZS) inSeptember 2015. The increase was attributed to higher in-tensity Fixed Target (FT) operation and poorer extractionefficiency, and reported to the IEFC [1]. Since this eventthe awareness of the impact of slow extraction losses on theoperation and maintenance of the SPS has been heightened.This is particularly pertinent in light of tightening limits ondose to personnel and recent requests for increased intensi-ties, as well as ambitious future experimental proposals inthe North Area (NA), such as the SPS Beam Dump Facility(BDF) [2]. To follow up these issues the SPS Losses andActivation Working Group (SLAWG) was formed.The MD programme for 2016 was originally foreseen totest the faster spill on a 1.2 second flat-top for the BDF andbenchmarksimulationsoftheextractionprocess, butthiswasnot possible due to the restrictions imposed by the TIDVG.Nevertheless, during operational set-up and re-alignmentof...

  4. Voltage regulation and power losses reduction in a wind farm integrated MV distribution network

    Science.gov (United States)

    Fandi, Ghaeth; Igbinovia, Famous Omar; Tlusty, Josef; Mahmoud, Rateb

    2018-01-01

    A medium-voltage (MV) wind production system is proposed in this paper. The system applies a medium-voltage permanent magnet synchronous generator (PMSG) as well as MV interconnection and distribution networks. The simulation scheme of an existing commercial electric-power system (Case A) and a proposed wind farm with a gearless PMSG insulated gate bipolar transistor (IGBT) power electronics converter scheme (Case B) is compared. The analyses carried out in MATLAB/Simulink environment shows an enhanced voltage profile and reduced power losses, thus, efficiency in installed IGBT power electronics devices in the wind farm. The resulting wind energy transformation scheme is a simple and controllable medium voltage application since it is not restrained by the IGBT power electronics voltage source converter (VSC) arrangement. Active and reactive power control is made possible with the aid of the gearless PMSG IGBT power converters.

  5. Effect of Multi-DG Installation to Loss Reduction in Distribution System

    Directory of Open Access Journals (Sweden)

    Nur Zahirah Mohd Ali

    2016-03-01

    Full Text Available Since last decade, Artificial Intelligence (AI methods have been used to solve complex DG problems because in most cases, they can provide global or near global solution. The major advantage of the AI methods is that they are relatively versatile for handling various qualitative constraints. AI methods mainly include Artificial Neural Network (ANN, Expert System (ES, Genetic Algorithm (GA, Evolutionary Programming (EP, Ant Colony Optimization (ACO and Particle Swarm Optimization (PSO. The purpose of this paper is to present a new technique, namely Adaptive Embedded Clonal Evolutionary Programming (AECEP. The objective of the study is to employ AECEP optimization techniques for loss minimization. This technique was developed to optimally determine the location and sizing of DG. The IEEE 41- Bus RTS was implemented for testing several cases in terms of loading conditions.

  6. Economic Estimation of the Losses Caused by Surface Water Pollution Accidents in China From the Perspective of Water Bodies’ Functions

    Directory of Open Access Journals (Sweden)

    Hong Yao

    2016-01-01

    Full Text Available The number of surface water pollution accidents (abbreviated as SWPAs has increased substantially in China in recent years. Estimation of economic losses due to SWPAs has been one of the focuses in China and is mentioned many times in the Environmental Protection Law of China promulgated in 2014. From the perspective of water bodies’ functions, pollution accident damages can be divided into eight types: damage to human health, water supply suspension, fishery, recreational functions, biological diversity, environmental property loss, the accident’s origin and other indirect losses. In the valuation of damage to people’s life, the procedure for compensation of traffic accidents in China was used. The functional replacement cost method was used in economic estimation of the losses due to water supply suspension and loss of water’s recreational functions. Damage to biological diversity was estimated by recovery cost analysis and damage to environmental property losses were calculated using pollutant removal costs. As a case study, using the proposed calculation procedure the economic losses caused by the major Songhuajiang River pollution accident that happened in China in 2005 have been estimated at 2263 billion CNY. The estimated economic losses for real accidents can sometimes be influenced by social and political factors, such as data authenticity and accuracy. Besides, one or more aspects in the method might be overestimated, underrated or even ignored. The proposed procedure may be used by decision makers for the economic estimation of losses in SWPAs. Estimates of the economic losses of pollution accidents could help quantify potential costs associated with increased risk sources along lakes/rivers but more importantly, highlight the value of clean water to society as a whole.

  7. Economic Estimation of the Losses Caused by Surface Water Pollution Accidents in China From the Perspective of Water Bodies’ Functions

    Science.gov (United States)

    Yao, Hong; You, Zhen; Liu, Bo

    2016-01-01

    The number of surface water pollution accidents (abbreviated as SWPAs) has increased substantially in China in recent years. Estimation of economic losses due to SWPAs has been one of the focuses in China and is mentioned many times in the Environmental Protection Law of China promulgated in 2014. From the perspective of water bodies’ functions, pollution accident damages can be divided into eight types: damage to human health, water supply suspension, fishery, recreational functions, biological diversity, environmental property loss, the accident’s origin and other indirect losses. In the valuation of damage to people’s life, the procedure for compensation of traffic accidents in China was used. The functional replacement cost method was used in economic estimation of the losses due to water supply suspension and loss of water’s recreational functions. Damage to biological diversity was estimated by recovery cost analysis and damage to environmental property losses were calculated using pollutant removal costs. As a case study, using the proposed calculation procedure the economic losses caused by the major Songhuajiang River pollution accident that happened in China in 2005 have been estimated at 2263 billion CNY. The estimated economic losses for real accidents can sometimes be influenced by social and political factors, such as data authenticity and accuracy. Besides, one or more aspects in the method might be overestimated, underrated or even ignored. The proposed procedure may be used by decision makers for the economic estimation of losses in SWPAs. Estimates of the economic losses of pollution accidents could help quantify potential costs associated with increased risk sources along lakes/rivers but more importantly, highlight the value of clean water to society as a whole. PMID:26805869

  8. Economic Estimation of the Losses Caused by Surface Water Pollution Accidents in China From the Perspective of Water Bodies' Functions.

    Science.gov (United States)

    Yao, Hong; You, Zhen; Liu, Bo

    2016-01-22

    The number of surface water pollution accidents (abbreviated as SWPAs) has increased substantially in China in recent years. Estimation of economic losses due to SWPAs has been one of the focuses in China and is mentioned many times in the Environmental Protection Law of China promulgated in 2014. From the perspective of water bodies' functions, pollution accident damages can be divided into eight types: damage to human health, water supply suspension, fishery, recreational functions, biological diversity, environmental property loss, the accident's origin and other indirect losses. In the valuation of damage to people's life, the procedure for compensation of traffic accidents in China was used. The functional replacement cost method was used in economic estimation of the losses due to water supply suspension and loss of water's recreational functions. Damage to biological diversity was estimated by recovery cost analysis and damage to environmental property losses were calculated using pollutant removal costs. As a case study, using the proposed calculation procedure the economic losses caused by the major Songhuajiang River pollution accident that happened in China in 2005 have been estimated at 2263 billion CNY. The estimated economic losses for real accidents can sometimes be influenced by social and political factors, such as data authenticity and accuracy. Besides, one or more aspects in the method might be overestimated, underrated or even ignored. The proposed procedure may be used by decision makers for the economic estimation of losses in SWPAs. Estimates of the economic losses of pollution accidents could help quantify potential costs associated with increased risk sources along lakes/rivers but more importantly, highlight the value of clean water to society as a whole.

  9. CGHregions: Dimension Reduction for Array CGH Data with Minimal Information Loss

    Directory of Open Access Journals (Sweden)

    Mark A. van de Wiel

    2007-01-01

    Full Text Available An algorithm to reduce multi-sample array CGH data from thousands of clones to tens or hundreds of clone regions is introduced. This reduction of the data is performed such that little information is lost, which is possible due to the high dependencies between neighboring clones. The algorithm is explained using a small example. The potential beneficial effects of the algorithm for downstream analysis are illustrated by re-analysis of previously published colorectal cancer data. Using multiple testing corrections suitable for these data, we provide statistical evidence for genomic differences on several clone regions between MSI+ and CIN+ tumors. The algorithm, named CGHregions, is available as an easy-to-use script in R.

  10. Qualitative Perspectives from African American Youth and Caregivers for Developing the Families Improving Together (FIT) for Weight Loss Intervention.

    Science.gov (United States)

    Kitzman-Ulrich, Heather E; Wilson, Dawn K; Lyerly, Jordan E

    2016-09-01

    This study obtained qualitative data from African American (AA) youth and caregiver dyads to inform the Families Improving Together (FIT) for Weight Loss Trial. Focus groups were conducted with 55 AA parent and caregiver dyads to gather perspectives on facilitators and barriers, motivators, and program preferences for health and weight loss using a socio-ecological framework. Four main themes emerged: using a positive health promotion framework for weight loss programs, social support and the role of parents in providing positive support, using a socio-ecological approach to examine factors that contribute to weight, and creating programs that are convenient, fun, and reduce barriers to participation. The findings from this study were used to develop the FIT intervention and indicate important individual, interpersonal, and environmental factors to consider when developing weight management and healthy lifestyle programs for AA families.

  11. Food loss and Waste Reduction as an Integral Part of a Circular Economy

    Directory of Open Access Journals (Sweden)

    Maria Virginia Vilariño

    2017-05-01

    Full Text Available One-third of food produced for human consumption is lost or wasted globally, which amounts to about 1.3 billion tons per year. An updated review of global food loss and waste (FLW is presented, as well as the related environmental, social and economic impacts, based on existing data and peer-reviewed literature. The authors reflect on the different food waste patterns and challenges faced by diverse regions around the world. The scale of FLW throughout the food value chain is analyzed, from agricultural production down to household consumption and disposal. FLW represent a waste of resources used in each production stage, such as land, water and energy; FLW also contributes to unnecessary increase of greenhouse gas (GHG emissions. The environmental and socio-economic impacts of FLW are analyzed based on reviewed life cycle assessments. Providing insights into key concepts around FLW, this article highlights the scale of the problem at a global and regional level. It also reflects on the main challenges for implementing strategies to reduce FLW and the implications for policy-making.

  12. Reduction of the suction losses through reed valves in hermetic reciprocating compressors using a magnet coil

    Science.gov (United States)

    Hopfgartner, J.; Posch, S.; Zuber, B.; Almbauer, R.; Krischan, K.; Stangl, S.

    2017-08-01

    Reed valves are widely used in hermetic reciprocating compressors and are responsible for a large part of the thermodynamic losses. Especially, the suction valve, which is opened nearly during the whole suction stroke, has a big potential for improvement. Usually, suction valves are opened only by vacuum created by the moving piston and should be closed before the compression stroke starts to avoid a reversed mass-flow through the valve. Therefore, the valves are prestressed, which results on the other hand in a higher flow resistance. In this work, a suction valve is investigated, which is not closed by the preload of the valve but by an electromagnetic coil located in the suction muffler neck. Shortly before the piston reaches its bottom dead centre, voltage is applied to the coil and a magnetic force is generated which pulls the valve shut. Thereby, the flow resistance through the valve can be reduced by changing the preload on the reed valve because it is no longer needed to close the valve. The investigation of this adapted valve and the electromagnetic coil is firstly done by numerical simulations including fluid structure interactions of the reed valves of a reciprocating compressor and secondly by experiments made on a calorimeter test bench.

  13. Beam loss reduction by magnetic shielding using beam pipes and bellows of soft magnetic materials

    Science.gov (United States)

    Kamiya, J.; Ogiwara, N.; Hotchi, H.; Hayashi, N.; Kinsho, M.

    2014-11-01

    One of the main sources of beam loss in high power accelerators is unwanted stray magnetic fields from magnets near the beam line, which can distort the beam orbit. The most effective way to shield such magnetic fields is to perfectly surround the beam region without any gaps with a soft magnetic high permeability material. This leads to the manufacture of vacuum chambers (beam pipes and bellows) with soft magnetic materials. A Ni-Fe alloy (permalloy) was selected for the material of the pipe parts and outer bellows parts, while a ferritic stainless steel was selected for the flanges. An austenitic stainless steel, which is non-magnetic material, was used for the inner bellows for vacuum tightness. To achieve good magnetic shielding and vacuum performances, a heat treatment under high vacuum was applied during the manufacturing process of the vacuum chambers. Using this heat treatment, the ratio of the integrated magnetic flux density along the beam orbit between the inside and outside of the beam pipe and bellows became small enough to suppress beam orbit distortion. The outgassing rate of the materials with this heat treatment was reduced by one order magnitude compared to that without heat treatment. By installing the beam pipes and bellows of soft magnetic materials as part of the Japan Proton Accelerator Research Complex 3 GeV rapid cycling synchrotron beam line, the closed orbit distortion (COD) was reduced by more than 80%. In addition, a 95.5% beam survival ratio was achieved by this COD improvement.

  14. The emotional impact of loss narratives: event severity and narrative perspectives.

    Science.gov (United States)

    Habermas, Tilmann; Diel, Verena

    2010-06-01

    Out of the complex influences of event, narrative and listener characteristics on narrative emotions, this paper focuses on event severity, narrative perspectives, mood, and dispositions for emotion regulation and empathy. Event severity and perspective representation were systematically varied in sad autobiographical narratives to study their influence on quantity and quality of readers' emotional response. Each of three stories were manipulated to contain elaborated perspectives, only the past protagonists' perspective (dramatic narration), and very little perspectives at all (impersonal narration). We predicted that event severity influences the quantity of emotional response, while degree of perspective representation influences plausibility and whether emotional responses are sympathetic or interactional, that is, directed against the narrator. Hypotheses were confirmed except for plausibility, and perspective representation had an effect only on anger against and dislike of the narrator. In a second study, impersonal narration evoked anger at and negative evaluations of the narrator which were related to blaming the narrator for showing too little emotional involvement. The generalizability of findings across emotions and implications for sharing of emotions in everyday and clinical settings are discussed.

  15. Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction

    Energy Technology Data Exchange (ETDEWEB)

    Kyrpides, Nikos; Anderson, Iain; Rodriguez, Jason; Susanti, Dwi; Porat, Iris; Reich, Claudia; Ulrich, Luke E.; Elkins, James G.; Mavromatis, Kostas; Lykidis, Athanasios; Kim, Edwin; Thompson, Linda S.; Nolan, Matt; Land, Miriam; Copeland, Alex; Lapidus, Alla; Lucas, Susan; Detter, Chris; Zhulin, Igor B.; Olsen, Gary J.; Whitman, William; Mukhopadhyay, Biswarup; Bristow, James; Kyrpides, Nikos

    2008-01-01

    We report the complete genome of Thermofilum pendens, a deep-branching, hyperthermophilic member of the order Thermoproteales within the archaeal kingdom Crenarchaeota. T. pendens is a sulfur-dependent, anaerobic heterotroph isolated from a solfatara in Iceland. It is an extracellular commensal, requiring an extract of Thermoproteus tenax for growth, and the genome sequence reveals that biosynthetic pathways for purines, most amino acids, and most cofactors are absent. In fact T. pendens has fewer biosynthetic enzymes than obligate intracellular parasites, although it does not display other features common among obligate parasites and thus does not appear to be in the process of becoming a parasite. It appears that T. pendens has adapted to life in an environment rich in nutrients. T. pendens was known to utilize peptides as an energy source, but the genome reveals substantial ability to grow on carbohydrates. T. pendens is the first crenarchaeote and only the second archaeon found to have a transporter of the phosphotransferase system. In addition to fermentation, T. pendens may gain energy from sulfur reduction with hydrogen and formate as electron donors. It may also be capable of sulfur-independent growth on formate with formate hydrogenlyase. Additional novel features are the presence of a monomethylamine:corrinoid methyltransferase, the first time this enzyme has been found outside of Methanosarcinales, and a presenilin-related protein. Predicted highly expressed proteins do not include housekeeping genes, and instead include ABC transporters for carbohydrates and peptides, and CRISPR-associated proteins.

  16. Weight loss for reduction of proteinuria in diabetic nephropathy: Comparison with angiotensin-converting enzyme inhibitor therapy

    Directory of Open Access Journals (Sweden)

    M R Patil

    2013-01-01

    Full Text Available Reduction of weight in obese type 2 diabetes mellitus (T2DM individuals is emerging as a significant strategy in the reduction of proteinuria in diabetic nephropathy along with control of hyperglycemia, hypertension, and dyslipidemia. The objective was to evaluate the reduction in 24-h proteinuria in T2DM patients with nephropathy by weight loss, with conventional therapy (angiotensin-converting enzyme [ACE] inhibitors as the control arm. A prospective, randomized controlled trial was conducted between June 2010 and May 2011. T2DM patients with confirmed nephropathy by 24-h urinary protein estimation with a body mass index (BMI of >25 kg/m 2 were studied. Patients who had nondiabetic nephropathy, uncontrolled hypertension (>125/75 mmHg irrespective of antihypertensive drugs, excess weight due to edema or obesity due to other specific diseases, alcoholics, smokers, and patients who were on hemodialysis were excluded from the study. The patients were divided into three groups, namely, group A, patients on ACE inhibitor therapy; group B, patients on lifestyle modifications for weight loss; and group C, patients on an antiobesity drug (orlistat and lifestyle modifications. At the end of 6 months, all the three groups were compared. Data were analyzed using software SPSS version 15.0. This study encompassed a total of 88 patients; 12 patients were dropped during the study period and 76 (group A: 22, group B: 23, and group C: 31 patients remained. The mean age of the patients was 58.36 ± 10.87 years (range: 30-70 years. At baseline, age, gender, mean BMI, waist-to-hip ratio (WHR, and 24-h proteinuria did not vary significantly among the three groups. At 6 months, the mean BMI significantly decreased in group C ( P < 0.001 compared to that in the other two groups. Among the parameters BMI and WHR, the proportional form of BMI correlated well with the degree of reduction in proteinuria (r = 0.397, P = 0.01. Reduction in weight using lifestyle

  17. Fiscal 1998 research report on the total electric power loss reduction project for Myanmer; 1998 nendo Myanmer koku denryoku soshitsu sogo teigen project chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    As a part of Japanese clean development mechanism, study was made on reduction of greenhouse effect gas emission from thermal power plants by reduction of power transmission and distribution losses of power systems in Myanmer. Study was made on technical power transmission and distribution losses for the national grid transmission system, 33kV sub- transmission system of Thaketa substation in Yangong city, and 6.6kV and 400V distribution systems of Latha and Lanmadaw townships in the downtown area of Yangong. Countermeasures for power loss reduction were considered on the basis of the study result. The loss reduction project plan includes a construction cost of 5,134,000US$, loss reduction of 7,726kW, and loss reduction of 33,213,000kWh. The project feasibility and profitability were evaluated by comparison between a financial internal rate of return (FIRR) and an opportunity cost assuming that a discount rate is the opportunity cost. As a result, FIRR was 17.36% and the discount rate was 8.89% in Myanmer. (NEDO)

  18. Distributed generation and their remuneration in the reduction of losses; Geracao distribuida e sua remuneracao na reducao de perdas

    Energy Technology Data Exchange (ETDEWEB)

    Chaves, Francisco David Moya; Jannuzzi, Gilberto de Martino [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Fac. de Engenharia Mecanica; Silva, Luiz Carlos Pereira da [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Fac. de Engenharia Eletrica e de Computacao

    2008-07-01

    The problematic associated to the Distribution Generation (DG) impact has several implications (economic, technical and environmental). The DG can to influence positive (reduction) or negatively (increase) about the level of losses. The impacts caused by the use of DG influence directly on the economic incentives that can get the DG. This paper presents some of the benefits and technical limitations in the use of DG in the provision of active and reactive power for each of the levels of transmission, sub transmission and distribution. An economic review where there is a decrease in the total cost of production of electric energy by the use of DG is shown. This reducing costs, can be used as an additional remuneration for the DG or used also in new investment in the expansion of DG without overlooking that within these technologies, deals are the Renewable Energy Sources. (author)

  19. Loss of reduction and complications of coracoclavicular ligament reconstruction with autogenous tendon graft in acute acromioclavicular dislocations.

    Science.gov (United States)

    Choi, Nam Hong; Lim, Seok Min; Lee, Sang Young; Lim, Tae Kang

    2017-04-01

    This study was conducted to report loss of reduction and complications after single-tunnel coracoclavicular (CC) ligament reconstruction with autogenous semitendinosus tendon graft for acute acromioclavicular (AC) joint dislocations. This retrospective study included patients with acute, unstable AC dislocations (surgery within 6 weeks after trauma). We excluded patients with chronic injury and distal clavicle fractures with CC ligaments disruption. We measured the CC distance on anteroposterior radiographs of both clavicles, preoperatively, immediately postoperatively, and at the final follow-up visit. We evaluated clinical outcomes using the American Shoulder and Elbow Surgeons Shoulder Assessment and the University of California, Los Angeles Shoulder Rating Scale scores and perioperative complications. There were 30 patients (27 men and 3 women) with mean age of 41 years (range, 19-70 years). The mean follow-up period was 31 months (range, 12-186 months). Mean CC distance was 15.5 ± 3.7 mm (84% ± 14% of the contralateral shoulder) preoperatively, 8.9 ± 2.6 mm (9% ± 40%) immediately postoperatively (P 25% increase of CC distance) developed in 14 patients (47%), and complications occurred in 6 patients (20%), including 3 distal clavicle fractures through the tunnel. Final clinical scores were significantly lower in patients with complications (27 vs. 33 of the University of California, Los Angeles assessment [P < .001] and 81 vs. 95 of the American Shoulder and Elbow Surgeons Shoulder assessment [P < .001]). In acute AC joint dislocation, single-tunnel CC ligament reconstruction using autogenous tendon graft resulted in loss of reduction rate of 47% and a complication rate of 20%. The development of complications adversely affected clinical outcomes. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  20. Missing the target: including perspectives of women with overweight and obesity to inform stigma-reduction strategies.

    Science.gov (United States)

    Puhl, R M; Himmelstein, M S; Gorin, A A; Suh, Y J

    2017-03-01

    Pervasive weight stigma and discrimination have led to ongoing calls for efforts to reduce this bias. Despite increasing research on stigma-reduction strategies, perspectives of individuals who have experienced weight stigma have rarely been included to inform this research. The present study conducted a systematic examination of women with high body weight to assess their perspectives about a broad range of strategies to reduce weight-based stigma. Women with overweight or obesity ( N  = 461) completed an online survey in which they evaluated the importance, feasibility and potential impact of 35 stigma-reduction strategies in diverse settings. Participants (91.5% who reported experiencing weight stigma) also completed self-report measures assessing experienced and internalized weight stigma. Most participants assigned high importance to all stigma-reduction strategies, with school-based and healthcare approaches accruing the highest ratings. Adding weight stigma to existing anti-harassment workplace training was rated as the most impactful and feasible strategy. The family environment was viewed as an important intervention target, regardless of participants' experienced or internalized stigma. These findings underscore the importance of including people with stigmatized identities in stigma-reduction research; their insights provide a necessary and valuable contribution that can inform ways to reduce weight-based inequities and prioritize such efforts.

  1. Basin characteristics and nutrient losses:the EUROHARP catchment network perspective

    Czech Academy of Sciences Publication Activity Database

    Bouraoui, F.; Grizzetti, B.; Adelskold, G.; Behrendt, H.; Miguel, I.; Silgram, M.; Gómez, S.; Granlund, K.; Hoffmann, L.; Kronvang, B.; Lázár, A.; Mimikou, M.; Passarella, G.; Panagos, P.; Reisser, H.; Schwarzl, B.; Siderius, C.; Sileika, A.S.; Smit, P. M.; Sugrue, R.; Liedekerke, M.; Žaloudík, Jiří

    2009-01-01

    Roč. 11, č. 3 (2009), s. 515-525 ISSN 1464-0325 Institutional research plan: CEZ:AV0Z6087904 Keywords : EUROHARP * geological * hydro-geological perspectives Subject RIV: DJ - Water Pollution ; Quality Impact factor: 2.225, year: 2009

  2. Comparison of Two Methods of Bolus and Infusion of Tranexamic Acid in Reduction of Blood Loss in Total Knee Arthroplasty

    Directory of Open Access Journals (Sweden)

    Mohammadreza Moshari

    2018-01-01

    Full Text Available AbstractBackground: So far, many studies have been performed to determine the optimal dose and regimen of tranexamic acid to reduce preoperative and postoperative blood loss in primary total knee arthroplasty. In the present study, two different methods of administration (bolus and infusion, were compared.Materials and Methods: Forty patients were randomized in the two groups (A and B of 20 patients each. All patients received 500 mg tranexamic acid before inflation of tourniquet. Group A (mean age, 64± 6.1 years received 500 mg tranexamic acid 10 minutes before loosening of tourniquet and group B (mean age, 63.5 ± 7.7 years received 500 mg tranexamic acid through IV infusion during 6 hours from the time of tourniquet loosening (total dose of TA, 1 g in both groups. Intraoperative blood loss,postoperative drainage (in 6 and 12 hours, blood transfusion (in 48 hours, and decrease in hematocrit and hemoglobin (6 and 12 hours later, were compared between the two groups.Results: The patients in group B had lower intra- and postoperative blood loss in 6 and 12 hours and also had lower decrease in hemoglobin, and their packed cell transfusion rate was significantly lower compared to the group A.Conclusion: The findings of this study indicated that infusion administration of tranexamic acid in primary total knee arthroplasty, was more effective in the reduction of perioperative blood loss as well as need for blood transfusion in 48 hours.

  3. Suicide Postvention in the Department of Defense: Evidence, Policies and Procedures, and Perspectives of Loss Survivors

    Science.gov (United States)

    2015-01-01

    of Forensic Sciences, American Associa- tion of Suicidology, Association of Vital Records and Health Statistics, CDC, International Association of...that stress responses are normal reactions to abnormal situations. ◦ Do not pathologize normal grief reactions. ◦ Do not say, “All that anger will...Journal of Forensic Sciences, Vol. 33, No. 6, November 1988, pp. 1445–1456. Rosenblatt, Paul C., “A Social Constructionist Perspective on Cultural

  4. Optoelectronic insights into the photovoltaic losses from photocurrent, voltage, and energy perspectives

    Science.gov (United States)

    Shang, Aixue; An, Yidan; Ma, Dong; Li, Xiaofeng

    2017-08-01

    Photocurrent and voltage losses are the fundamental limitations for improving the efficiency of photovoltaic devices. It is indeed that a comprehensive and quantitative differentiation of the performance degradation in solar cells will promote the understanding of photovoltaic physics as well as provide a useful guidance to design highly-efficient and cost-effective solar cells. Based on optoelectronic simulation that addresses electromagnetic and carrier-transport responses in a coupled finite-element method, we report a detailed quantitative analysis of photocurrent and voltage losses in solar cells. We not only concentrate on the wavelength-dependent photocurrent loss, but also quantify the variations of photocurrent and operating voltage under different forward electrical biases. Further, the device output power and power losses due to carrier recombination, thermalization, Joule heat, and Peltier heat are studied through the optoelectronic simulation. The deep insight into the gains and losses of the photocurrent, voltage, and energy will contribute to the accurate clarifications of the performance degradation of photovoltaic devices, enabling a better control of the photovoltaic behaviors for high performance.

  5. Winter reduction in body mass in a very small, nonhibernating mammal: consequences for heat loss and metabolic rates.

    Science.gov (United States)

    Taylor, Jan R E; Rychlik, Leszek; Churchfield, Sara

    2013-01-01

    Low temperatures in northern winters are energetically challenging for mammals, and a special energetic burden is expected for diminutive species like shrews, which are among the smallest of mammals. Surprisingly, shrews shrink their body size in winter and reduce body and brain mass, an effect known as Dehnel's phenomenon, which is suggested to lower absolute energy intake requirements and thereby enhance survival when food availability is low. Yet reduced body size coupled with higher body-surface-to-mass ratio in these tiny mammals may result in thermoregulatory heat production at a given temperature constituting a larger proportion of the total energy expenditure. To evaluate energetic consequences of reduced body size in winter, we investigated common shrews Sorex araneus in northeastern Poland. Average body mass decreased by 19.0% from summer to winter, and mean skull depth decreased by 13.1%. There was no difference in Dehnel's phenomenon between years despite different weather conditions. The whole-animal thermal conductance (proportional to absolute heat loss) in shrews was 19% lower in winter than in summer; the difference between the two seasons remained significant after correcting for body mass and was caused by improved fur insulation in winter. Thermogenic capacity of shrews, although much enhanced in winter, did not reach its full potential of increase, and this corresponded with relatively mild subnivean temperatures. These findings indicate that, despite their small body size, shrews effectively decrease their costs of thermoregulation. The recorded decrease in body mass from summer to winter resulted in a reduction of overall resting metabolic rate (in thermoneutrality) by 18%. This, combined with the reduced heat loss, should translate to food requirements that are substantially lower than would be the case if shrews did not undergo seasonal decrease in body mass.

  6. Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo.

    Science.gov (United States)

    Kim, Hyung-Wook; Choi, Won-Seok; Sorscher, Noah; Park, Hyung Joon; Tronche, François; Palmiter, Richard D; Xia, Zhengui

    2015-09-01

    Inhibition of mitochondrial complex I activity is hypothesized to be one of the major mechanisms responsible for dopaminergic neuron death in Parkinson's disease. However, loss of complex I activity by systemic deletion of the Ndufs4 gene, one of the subunits comprising complex I, does not cause dopaminergic neuron death in culture. Here, we generated mice with conditional Ndufs4 knockout in dopaminergic neurons (Ndufs4 conditional knockout mice [cKO]) to examine the effect of complex I inhibition on dopaminergic neuron function and survival during aging and on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment in vivo. Ndufs4 cKO mice did not show enhanced dopaminergic neuron loss in the substantia nigra pars compacta or dopamine-dependent motor deficits over the 24-month life span. These mice were just as susceptible to MPTP as control mice. However, compared with control mice, Ndufs4 cKO mice exhibited an age-dependent reduction of dopamine in the striatum and increased α-synuclein phosphorylation in dopaminergic neurons of the substantia nigra pars compacta. We also used an inducible Ndufs4 knockout mouse strain (Ndufs4 inducible knockout) in which Ndufs4 is conditionally deleted in all cells in adult to examine the effect of adult onset, complex I inhibition on MPTP sensitivity of dopaminergic neurons. The Ndufs4 inducible knockout mice exhibited similar sensitivity to MPTP as control littermates. These data suggest that mitochondrial complex I inhibition in dopaminergic neurons does contribute to dopamine loss and the development of α-synuclein pathology. However, it is not sufficient to cause cell-autonomous dopaminergic neuron death during the normal life span of mice. Furthermore, mitochondrial complex I inhibition does not underlie MPTP toxicity in vivo in either cell autonomous or nonautonomous manner. These results provide strong evidence that inhibition of mitochondrial complex I activity is not sufficient to cause dopaminergic neuron

  7. The Effects of Hearing Aid Directional Microphone and Noise Reduction Processing on Listening Effort in Older Adults with Hearing Loss.

    Science.gov (United States)

    Desjardins, Jamie L

    2016-01-01

    Older listeners with hearing loss may exert more cognitive resources to maintain a level of listening performance similar to that of younger listeners with normal hearing. Unfortunately, this increase in cognitive load, which is often conceptualized as increased listening effort, may come at the cost of cognitive processing resources that might otherwise be available for other tasks. The purpose of this study was to evaluate the independent and combined effects of a hearing aid directional microphone and a noise reduction (NR) algorithm on reducing the listening effort older listeners with hearing loss expend on a speech-in-noise task. Participants were fitted with study worn commercially available behind-the-ear hearing aids. Listening effort on a sentence recognition in noise task was measured using an objective auditory-visual dual-task paradigm. The primary task required participants to repeat sentences presented in quiet and in a four-talker babble. The secondary task was a digital visual pursuit rotor-tracking test, for which participants were instructed to use a computer mouse to track a moving target around an ellipse that was displayed on a computer screen. Each of the two tasks was presented separately and concurrently at a fixed overall speech recognition performance level of 50% correct with and without the directional microphone and/or the NR algorithm activated in the hearing aids. In addition, participants reported how effortful it was to listen to the sentences in quiet and in background noise in the different hearing aid listening conditions. Fifteen older listeners with mild sloping to severe sensorineural hearing loss participated in this study. Listening effort in background noise was significantly reduced with the directional microphones activated in the hearing aids. However, there was no significant change in listening effort with the hearing aid NR algorithm compared to no noise processing. Correlation analysis between objective and self

  8. Responding to Cultural Loss: Providing an Integral Indigenous Perspective of a "Kichwa Child"

    Science.gov (United States)

    Maigua, Yolanda Terán; Gutierrez-Gomez, Cathy

    2016-01-01

    As Indigenous populations around the world migrate, urbanize, and come into contact with a variety of other cultures, they risk loss of their ancient languages and cultural practices. In 2007, the UN General Assembly adopted the Declaration on the Rights of Indigenous Peoples. In addition to the broader human rights like employment, security, and…

  9. Coarticulation in Early Vocalizations by Children with Hearing Loss: A Locus Perspective

    Science.gov (United States)

    Morrison, Helen Mccaffrey

    2012-01-01

    Locus equations derived from productions by three children with hearing loss revealed sensory and motor influences on anticipatory coarticulation. Participants who received auditory access to speech via hearing aids and cochlear implants at different ages (5-39 months) were recorded at approximately 6 and 12 months after hearing technology…

  10. Weight loss and waist reduction is associated with improvement in gastroesophageal disease reflux symptoms: A longitudinal study of 15 295 subjects undergoing health checkups.

    Science.gov (United States)

    Park, S-K; Lee, T; Yang, H-J; Park, J H; Sohn, C I; Ryu, S; Park, D I

    2017-05-01

    General obesity and abdominal obesity is an established risk factor of gastroesophageal reflux disease (GERD). However, the influence of weight or waist change on improvement of GERD is unclear. Our aim was to investigate if weight loss or waist reduction improves GERD symptoms and esophagitis. A retrospective longitudinal study of 15 295 subjects who underwent gastroscopy for a health checkup and reported GERD symptoms between 2011 and 2013, and repeated a checkup until 2014 was conducted. The improvement of GERD symptoms and esophagitis according to weight loss (≥-2, -0.5 to -2 kg/m 2 in body mass index [BMI]), waist reduction (≥-5, -0.1 to -0.5 cm) and baseline BMI/waist circumference (WC) categories was assessed using logistic regression. Weight loss or waist reduction was associated with improvement in GERD symptoms only in subjects with general or abdominal obesity. Among subjects with general obesity (BMI ≥25 kg/m 2 ) and decreased ≥2 kg/m 2 in BMI, the adjusted odds ratio (OR) of improvement in GERD symptoms was 2.34 (95% confidence interval [CI] 1.70-2.83). Among subjects with abdominal obesity (WC ≥90 cm) and decreased ≥5 cm in WC, the corresponding OR was 2.16 (95% CI 1.56-2.90). There was no association between weight loss or waist reduction and improvement in esophagitis. Weight loss or waist reduction was associated with improvement in GERD symptoms only in subjects with general or abdominal obesity. Weight loss or waist reduction will be an important treatment option in obese patients. © 2016 John Wiley & Sons Ltd.

  11. Urban Expansion and Agricultural Land Loss in China: A Multiscale Perspective

    Directory of Open Access Journals (Sweden)

    Kaifang Shi

    2016-08-01

    Full Text Available China’s rapid urbanization has contributed to a massive agricultural land loss that could threaten its food security. Timely and accurate mapping of urban expansion and urbanization-related agricultural land loss can provide viable measures to be taken for urban planning and agricultural land protection. In this study, urban expansion in China from 2001 to 2013 was mapped using the nighttime stable light (NSL, normalized difference vegetation index (NDVI, and water body data. Urbanization-related agricultural land loss during this time period was then evaluated at national, regional, and metropolitan scales by integrating multiple sources of geographic data. The results revealed that China’s total urban area increased from 31,076 km2 in 2001 to 80,887 km2 in 2013, with an average annual growth rate of 13.36%. This widespread urban expansion consumed 33,080 km2 of agricultural land during this period. At a regional scale, the eastern region lost 18,542 km2 or 1.2% of its total agricultural land area. At a metropolitan scale, the Shanghai–Nanjing–Hangzhou (SNH and Pearl River Delta (PRD areas underwent high levels of agricultural land loss with a decrease of 6.12% (4728 km2 and 6.05% (2702 km2 of their total agricultural land areas, respectively. Special attention should be paid to the PRD, with a decline of 13.30% (1843 km2 of its cropland. Effective policies and strategies should be implemented to mitigate urbanization-related agricultural land loss in the context of China’s rapid urbanization.

  12. Rural health professionals' perspectives on providing grief and loss support in cancer care.

    Science.gov (United States)

    Breen, L J; O'Connor, M

    2013-11-01

    Research demonstrates considerable inequalities in service delivery and health outcomes for people with cancer living outside large metropolitan cities. Semi-structured interviews with 11 professionals providing grief and loss support for people with cancer and their families in rural, regional, and remote areas Western Australia revealed the challenges they faced in delivering such support. The data are presented in four themes - Inequity of regional versus metropolitan services, Strain of the 'Jack of all trades' role, Constraints to accessing professional development, and Challenges in delivering post-bereavement services. These challenges are likely to be of growing concern given that populations are declining in rural areas as Australia becomes increasingly urban. The findings have implications in enhancing the loss and grief support services available in rural, regional, and remote Western Australia, including those grieving the death of a loved one through cancer. © 2013 John Wiley & Sons Ltd.

  13. Performance and perspectives of the diamond based Beam Condition Monitor for beam loss monitoring at CMS

    CERN Document Server

    AUTHOR|(CDS)2080862

    2015-01-01

    At CMS, a beam loss monitoring system is operated to protect the silicon detectors from high particle rates, arising from intense beam loss events. As detectors, poly-crystalline CVD diamond sensors are placed around the beam pipe at several locations inside CMS. In case of extremely high detector currents, the LHC beams are automatically extracted from the LHC rings.Diamond is the detector material of choice due to its radiation hardness. Predictions of the detector lifetime were made based on FLUKA monte-carlo simulations and irradiation test results from the RD42 collaboration, which attested no significant radiation damage over several years.During the LHC operational Run1 (2010 â?? 2013), the detector efficiencies were monitored. A signal decrease of about 50 times stronger than expectations was observed in the in-situ radiation environment. Electric field deformations due to charge carriers, trapped in radiation induced lattice defects, are responsible for this signal decrease. This so-called polarizat...

  14. Urban expansion dynamics and natural habitat loss in China: a multiscale landscape perspective.

    Science.gov (United States)

    He, Chunyang; Liu, Zhifeng; Tian, Jie; Ma, Qun

    2014-09-01

    China's extensive urbanization has resulted in a massive loss of natural habitat, which is threatening the nation's biodiversity and socioeconomic sustainability. A timely and accurate understanding of natural habitat loss caused by urban expansion will allow more informed and effective measures to be taken for the conservation of biodiversity. However, the impact of urban expansion on natural habitats is not well-understood, primarily due to the lack of accurate spatial information regarding urban expansion across China. In this study, we proposed an approach that can be used to accurately summarize the dynamics of urban expansion in China over two recent decades (1992-2012), by integrating data on nighttime light levels, a vegetation index, and land surface temperature. The natural habitat loss during the time period was evaluated at the national, ecoregional, and local scales. The results revealed that China had experienced extremely rapid urban growth from 1992 to 2012 with an average annual growth rate of 8.74%, in contrast with the global average of 3.20%. The massive urban expansion has resulted in significant natural habitat loss in some areas in China. Special attention needs to be paid to the Pearl River Delta, where 25.79% or 1518 km(2) of the natural habitat and 41.99% or 760 km(2) of the local wetlands were lost during 1992-2012. This raises serious concerns about species viability and biodiversity. Effective policies and regulations must be implemented and enforced to sustain regional and national development in the context of rapid urbanization. © 2014 John Wiley & Sons Ltd.

  15. Perspectives for the treatment of sensorineural hearing loss by cellular regeneration of the inner ear.

    Science.gov (United States)

    Almeida-Branco, Mario S; Cabrera, Sonia; Lopez-Escamez, Jose A

    2015-01-01

    Sensorineural hearing loss is a caused by the loss of the cochlear hair cells with the consequent deafferentation of spiral ganglion neurons. Humans do not show endogenous cellular regeneration in the inner ear and there is no exogenous therapy that allows the replacement of the damaged hair cells. Currently, treatment is based on the use of hearing aids and cochlear implants that present different outcomes, some difficulties in auditory discrimination and a limited useful life. More advanced technology is hindered by the functional capacity of the remaining spiral ganglion neurons. The latest advances with stem cell therapy and cellular reprogramming have developed several possibilities to induce endogenous regeneration or stem cell transplantation to replace damaged inner ear hair cells and restore hearing function. With further knowledge of the cellular and molecular biology of the inner ear and its embryonic development, it will be possible to use induced stem cells as in vitro models of disease and as replacement cellular therapy. Investigation in this area is focused on generating cellular therapy with clinical use for the treatment of profound sensorineural hearing loss. Copyright © 2014 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial. All rights reserved.

  16. Baseline leptin and leptin reduction predict improvements in metabolic variables and long-term fat loss in obese children and adolescents: a prospective study of an inpatient weight-loss program

    NARCIS (Netherlands)

    Murer, S.B.; Knopfli, B.H.; Aeberli, I.; Jung, A.; Wildhaber, J.; Wildhaber-Brooks, J.; Zimmermann, M.B.

    2011-01-01

    Background: It is unclear whether high plasma leptin in obese individuals represents leptin resistance or whether individuals with marked reductions in leptin concentrations in response to weight loss may be at greater risk of regaining weight. Moreover, whether changes in leptin predict metabolic

  17. Reductions in knee joint forces with weight loss are attenuated by gait adaptations in class III obesity

    NARCIS (Netherlands)

    DeVita, Paul; Rider, Patrick; Hortobagyi, Tibor

    A consensus exists that high knee joint forces are a precursor to knee osteoarthritis and weight loss reduces these forces. Because large weight loss also leads to increased step length and walking velocity, knee contact forces may be reduced less than predicted by the magnitude of weight loss. The

  18. A Dutch Perspective on Coastal Louisiana Flood Risk Reduction and Landscape Stabilization

    National Research Council Canada - National Science Library

    Dijkman, Jos

    2007-01-01

    .... The project was aimed at identifying options for the long-term reduction of flood risks and landscape stabilization in Planning Areas I and 2 in Louisiana, in the framework of the Louisiana Coastal...

  19. Reduction of soil erosion and mercury losses in agroforestry systems compared to forests and cultivated fields in the Brazilian Amazon.

    Science.gov (United States)

    Béliveau, Annie; Lucotte, Marc; Davidson, Robert; Paquet, Serge; Mertens, Frédéric; Passos, Carlos J; Romana, Christine A

    2017-12-01

    In addition to causing physical degradation and nutrient depletion, erosion of cultivated soils in the Amazon affects aquatic ecosystems through the release of natural soil mercury (Hg) towards lakes and rivers. While traditional agriculture is generally cited as being among the main causes of soil erosion, agroforestry practices are increasingly appreciated for soil conservation. This study was carried out in family farms of the rural Tapajós region (Brazil) and aimed at evaluating soil erosion and associated Hg release for three land uses. Soils, runoff water and eroded sediments were collected at three sites representing a land cover gradient: a recently burnt short-cycle cropping system (SCC), a 2-year-old agroforestry system (AFS) and a mature forest (F). At each site, two PVC soil erosion plots (each composed of three 2 × 5 m isolated subplots) were implemented on steep and moderate slopes respectively. Sampling was done after each of the 20 rain events that occurred during a 1-month study period, in the peak of the 2011 rain season. Runoff volume and rate, as well as eroded soil particles with their Hg and cation concentrations were determined. Total Hg and cation losses were then calculated for each subplot. Erosion processes were dominated by land use type over rainfall or soil slope. Eroded soil particles, as well as the amount of Hg and cations (CaMgK) mobilized at the AFS site were similar to those at the F site, but significantly lower than those at the SCC site (p agroforestry systems, even in their early stages of implementation, are characterized by low erosion levels resembling those of local forest environments, thus contributing to the maintenance of soil integrity and to the reduction of Hg and nutrient mobility. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. A unified view of energetic efficiency in active drag reduction, thrust generation and self-propulsion through a loss coefficient with some applications

    Science.gov (United States)

    Arakeri, Jaywant H.; Shukla, Ratnesh K.

    2013-08-01

    An analysis of the energy budget for the general case of a body translating in a stationary fluid under the action of an external force is used to define a power loss coefficient. This universal definition of power loss coefficient gives a measure of the energy lost in the wake of the translating body and, in general, is applicable to a variety of flow configurations including active drag reduction, self-propulsion and thrust generation. The utility of the power loss coefficient is demonstrated on a model bluff body flow problem concerning a two-dimensional elliptical cylinder in a uniform cross-flow. The upper and lower boundaries of the elliptic cylinder undergo continuous motion due to a prescribed reflectionally symmetric constant tangential surface velocity. It is shown that a decrease in drag resulting from an increase in the strength of tangential surface velocity leads to an initial reduction and eventual rise in the power loss coefficient. A maximum in energetic efficiency is attained for a drag reducing tangential surface velocity which minimizes the power loss coefficient. The effect of the tangential surface velocity on drag reduction and self-propulsion of both bluff and streamlined bodies is explored through a variation in the thickness ratio (ratio of the minor and major axes) of the elliptical cylinders.

  1. Reduction of heat losses on the skid pipe system of a pusher type furnace; Verringerung der Waermeverluste am Tragrohrsystem eines Stossofens

    Energy Technology Data Exchange (ETDEWEB)

    Hoffelner, Mario; Winter, Franz [voestalpine Grobblech GmbH, Linz (Austria); Springer, Michael; Huegel, Frank [FBB Engineering GmbH, Moenchengladbach (Germany); Buhr, Andreas [Almatis GmbH, Frankfurt (Germany); Kockegey-Lorenz, Rainer [Almatis GmbH, Ludwigshafen (Germany)

    2013-06-15

    This paper discusses how energy consumption and energy loss can be reduced in reheating furnaces of hot rolling mills by new lightweight refractory materials and a new modular lining concept for the skid pipe insulation using pre-fabricated shells. The target is to optimise the hot rolling process from an energy point of view, and to reduce the operational cost of the furnaces. The new lightweight pre-fabricated shells based on the microporous castable and a thermotechnical optimised sandwich design can significantly reduce the heat losses compared to dense castable. Industrial application of the new system in a 110 t/h pusher type furnace at voestalpine Grobblech GmbH in Linz, Austria, resulted in reduction of heat loss about 30 %. The annualised energy saving gives a cost reduction of more than Euro 200,000 a year. Costs for the complete new lining about Euro 170,000 result in a payback period of less than one year. (orig.)

  2. Weight Loss and Comorbidity Resolution 3 Years After Bariatric Surgery-an Indian Perspective.

    Science.gov (United States)

    Nasta, Amrit Manik; Goel, Ramen; Dharia, Shefali; Goel, Madhu; Hamrapurkar, Shireen

    2018-04-03

    Bariatric surgery has seen a sharp rise in India in the last decade. India is one of the 10 most obese nations of the world, ranking second in number of type 2 diabetics. To evaluate clinical outcomes of bariatric surgery after 3 years of follow-up in terms of weight loss, co-morbidity resolution, complaints of gastroesophageal reflux disease and weight regain. All patients who underwent bariatric surgery from January to December 2013 with a minimum follow-up of 3 years were included in the study. Their demographic, preoperative, and postoperative data were prospectively maintained on Microsoft Office Excel and analyzed statistically. One hundred seventy-eight patients (157 lap. sleeve gastrectomy and 21 patients lap. RYGB) completed 3 years of follow-up. In the LSG group, patients had a pre-operative BMI 44.8 ± 8.33 kg/sq. m (mean ± S.D.) and excess body weight 52.3 ± 23.0 kg. In the RYGB group, pre-operative BMI was 42.7 ± 8.82 kg/sq. m and excess body weight 45 ± 18.7 kg. In the LSG group, % excess weight loss (EWL) at 1 year was 87.6 ± 24.4% and 3 years was 71.8 ± 26.7%. In the RYGB group, % EWL at 1 year was 97.2 ± 27.3% and at 3 years was 85.8 ± 25.3%. Diabetes resolution was seen in 32 (80%) in LSG group and 11 (91.7%) in RYGB group (Figs. 1, 2, 3, and 4). Our study reflects that there is no statistically significant difference between outcomes of sleeve gastrectomy and Roux-en-Y gastric bypass surgery in terms of weight loss and diabetes resolution at 3 years.

  3. Work-loss years among people diagnosed with diabetes: a reappraisal from a life course perspective.

    Science.gov (United States)

    von Bonsdorff, Mikaela B; von Bonsdorff, Monika E; Haanpää, Maija; Salonen, Minna; Mikkola, Tuija M; Kautiainen, Hannu; Eriksson, Johan G

    2018-05-01

    Early exit from the workforce has been proposed to be one of the unfavorable consequences of diabetes. We examined whether early exit from the workforce differed between persons who were and were not diagnosed with diabetes during their work career. The cohort included 12,726 individuals of the Helsinki Birth Cohort Study, born between 1934 and 1944. Using data from nationwide registers, the cohort was followed up from early adulthood until they transitioned into retirement or died. Work-loss years were estimated using the restricted mean work years method. During a follow-up of 382,328 person-years for men and 349 894 for women, 36.8% transitioned into old age pension and 63.2% exited workforce early. Among men, 40.5% of those with and 32.8% of those without diabetes transitioned into old age pension (p=0.003). The corresponding numbers for women were 48.6% and 40.4% (p = 0.013), respectively. Mean age at exit from the workforce was 60.1 (95% confidence interval [CI], 59.6 to 60.7) years among men with diabetes and 57.6 (95% CI, 57.2 to 58.0) years among men without diabetes (p = 0.016). Among women, corresponding ages were 61.4 (95% CI, 60.8 to 61.9) years for those with diabetes and 59.5 (95% CI, 59.3 to 59.7) years for those without diabetes (p work-loss years according to diabetes was 2.5 (95% CI 0.5 to 4.6) for men and 1.9 (95% CI 1.0 to 2.8) for women. Among individuals followed up throughout their work career, those with a diabetes diagnosis exited the workforce approximately two years later compared to those without diabetes.

  4. The estimated reduction in the odds of loss-of-control type crashes for sport utility vehicles equipped with electronic stability control.

    Science.gov (United States)

    Green, Paul E; Woodrooffe, John

    2006-01-01

    Using data from the NASS General Estimates System (GES), the method of induced exposure was used to assess the effects of electronic stability control (ESC) on loss-of-control type crashes for sport utility vehicles. Sport utility vehicles were classified into crash types generally associated with loss of control and crash types most likely not associated with loss of control. Vehicles were then compared as to whether ESC technology was present or absent in the vehicles. A generalized additive model was fit to assess the effects of ESC, driver age, and driver gender on the odds of loss of control. In addition, the effects of ESC on roads that were not dry were compared to effects on roads that were dry. Overall, the estimated percentage reduction in the odds of a loss-of-control crash for sport utility vehicles equipped with ESC was 70.3%. Both genders and all age groups showed reduced odds of loss-of-control crashes, but there was no significant difference between males and females. With respect to driver age, the maximum percentage reduction of 73.6% occurred at age 27. The positive effects of ESC on roads that were not dry were significantly greater than on roads that were dry.

  5. OMG do not say LOL: obese adolescents' perspectives on the content of text messages to enhance weight loss efforts.

    Science.gov (United States)

    Woolford, Susan J; Barr, Kathryn L C; Derry, Holly A; Jepson, Christina M; Clark, Sarah J; Strecher, Victor J; Resnicow, Kenneth

    2011-12-01

    Adolescents participating in weight loss programs experience difficulty adhering to behavior change recommendations. Communications technology provides a low cost means to increase the frequency of contact with adolescents which can improve their engagement and also lead to behavior change. Within a larger project on the development of tailored text messages for adolescents enrolled in an existing multidisciplinary weight management program, this study explored participants' perspectives about message content. A library of messages was developed focused on topics central to weight management. Four focus groups were conducted with a total of 24 participants from the weight management program to gage their reactions to the messages. Detailed notes from the focus groups were analyzed to assess the acceptability of individual messages and to identify overriding themes. Results indicate that participants were very enthusiastic about receiving text messages. They preferred messages that provided recipe ideas, included successful weight loss strategies used by peers, and requested feedback regarding their progress. They preferred positive, encouraging, and direct messages. They were unanimous that messages should include encouraging symbols (e.g., exclamation points and "smiley faces") as often as possible. They emphasized that any mention of unhealthy foods or behaviors would trigger them to eat those foods or engage in those behaviors. Text messaging acronyms (e.g., LOL) were considered too informal for messages from healthcare providers. This study suggests that including text messages in obesity interventions is acceptable to obese adolescents as a means of supporting their weight loss efforts, and it highlights the need for such messages to be carefully constructed.

  6. OMG Do Not Say LOL: Obese Adolescents’ Perspectives on the Content of Text Messages to Enhance Weight Loss Efforts

    Science.gov (United States)

    Woolford, Susan J.; Barr, Kathryn L.C.; Derry, Holly A.; Jepson, Christina M.; Clark, Sarah J.; Strecher, Victor J.; Resnicow, Kenneth

    2011-01-01

    Adolescents participating in weight loss programs experience difficulty adhering to behavior change recommendations. Communications technology provides a low cost means to increase the frequency of contact with adolescents which can improve their engagement and also lead to behavior change. Within a larger project on the development of tailored text messages for adolescents enrolled in an existing multidisciplinary weight management program, this study explored participants’ perspectives about message content. A library of messages was developed focused on topics central to weight management. Four focus groups were conducted with a total of 24 participants from the weight management program to gage their reactions to the messages. Detailed notes from the focus groups were analyzed to assess the acceptability of individual messages and to identify overriding themes. Results indicate that participants were very enthusiastic about receiving text messages. They preferred messages that provided recipe ideas, included successful weight loss strategies used by peers, and requested feedback regarding their progress. They preferred positive, encouraging, and direct messages. They were unanimous that messages should include encouraging symbols (e.g., exclamation points and “smiley faces”) as often as possible. They emphasized that any mention of unhealthy foods or behaviors would trigger them to eat those foods or engage in those behaviors. Text messaging acronyms (e.g., LOL) were considered too informal for messages from healthcare providers. This study suggests that including text messages in obesity interventions is acceptable to obese adolescents as a means of supporting their weight loss efforts, and it highlights the need for such messages to be carefully constructed. PMID:21869762

  7. Determinants of Successful Weight Loss After Using a Commercial Web-Based Weight Reduction Program for Six Months: Cohort Study

    OpenAIRE

    Postrach, Elisa; Aspalter, Rosa; Elbelt, Ulf; Koller, Michael; Longin, Rita; Schulzke, J?rg-Dieter; Valentini, Luzia

    2013-01-01

    Background The Internet is widely available and commonly used for health information; therefore, Web-based weight loss programs could provide support to large parts of the population in self-guided weight loss. Previous studies showed that Web-based weight loss interventions can be effective, depending on the quality of the program. The most effective program tools are visual progress charts or tools for the self-monitoring of weight, diet, and exercises. KiloCoach, a commercial program curre...

  8. Harm reduction in the USA: the research perspective and an archive to David Purchase.

    Science.gov (United States)

    Des Jarlais, Don C

    2017-07-26

    The history of harm reduction in the USA has led to the development of some of the most important methods for treating persons for drug use disorders, such as methadone and buprenorphine for opiate use disorder. However, there has been fierce political resistance to implementation and scale-up of harm reduction in the USA. This resistance is rooted in historical demonization of particular psychoactive drugs that were associated with stigmatized racial/ethnic groups.With the discovery of acquired immunodeficiency syndrome (AIDS) in 1981, harm reduction became important not only for treating substance use disorders, but for reducing transmission of blood-borne infection. However, within the context of the crack cocaine epidemic in the 1980s, it was very difficult to implement any programs that appeared to "condone" drug use.It was not until the late 1980s that syringe exchange programs began at the state and local level in the USA. With funding primarily from state and local governments and the support of the North American Syringe Exchange Network (NASEN), there are now approximately 200 programs for syringe exchange in the USA. Research has shown that these programs have been extremely effective in reducing human immunodeficiency virus (HIV) transmission among persons who inject drugs (PWID). The programs in the USA also offer many additional services for drug users, including condom distribution, referrals to substance abuse treatment, HIV, hepatitis C virus (HCV), hepatitis B virus (HBV) counseling and testing, overdose education and naloxone distribution to reverse for overdose.Currently, the USA is experiencing an opioid/heroin epidemic, with significant increases in overdose deaths among drug users. Much of this epidemic is occurring in suburban and rural of the country without harm reduction services. The current challenges for harm reduction and harm reduction research involve expansion of services to suburban and rural areas and implementation science on

  9. Characterization of adaptive statistical iterative reconstruction algorithm for dose reduction in CT: A pediatric oncology perspective

    International Nuclear Information System (INIS)

    Brady, S. L.; Yee, B. S.; Kaufman, R. A.

    2012-01-01

    Purpose: This study demonstrates a means of implementing an adaptive statistical iterative reconstruction (ASiR™) technique for dose reduction in computed tomography (CT) while maintaining similar noise levels in the reconstructed image. The effects of image quality and noise texture were assessed at all implementation levels of ASiR™. Empirically derived dose reduction limits were established for ASiR™ for imaging of the trunk for a pediatric oncology population ranging from 1 yr old through adolescence/adulthood. Methods: Image quality was assessed using metrics established by the American College of Radiology (ACR) CT accreditation program. Each image quality metric was tested using the ACR CT phantom with 0%–100% ASiR™ blended with filtered back projection (FBP) reconstructed images. Additionally, the noise power spectrum (NPS) was calculated for three common reconstruction filters of the trunk. The empirically derived limitations on ASiR™ implementation for dose reduction were assessed using (1, 5, 10) yr old and adolescent/adult anthropomorphic phantoms. To assess dose reduction limits, the phantoms were scanned in increments of increased noise index (decrementing mA using automatic tube current modulation) balanced with ASiR™ reconstruction to maintain noise equivalence of the 0% ASiR™ image. Results: The ASiR™ algorithm did not produce any unfavorable effects on image quality as assessed by ACR criteria. Conversely, low-contrast resolution was found to improve due to the reduction of noise in the reconstructed images. NPS calculations demonstrated that images with lower frequency noise had lower noise variance and coarser graininess at progressively higher percentages of ASiR™ reconstruction; and in spite of the similar magnitudes of noise, the image reconstructed with 50% or more ASiR™ presented a more smoothed appearance than the pre-ASiR™ 100% FBP image. Finally, relative to non-ASiR™ images with 100% of standard dose across the

  10. Characterization of adaptive statistical iterative reconstruction algorithm for dose reduction in CT: A pediatric oncology perspective

    Energy Technology Data Exchange (ETDEWEB)

    Brady, S. L.; Yee, B. S.; Kaufman, R. A. [Department of Radiological Sciences, St. Jude Children' s Research Hospital, Memphis, Tennessee 38105 (United States)

    2012-09-15

    Purpose: This study demonstrates a means of implementing an adaptive statistical iterative reconstruction (ASiR Trade-Mark-Sign ) technique for dose reduction in computed tomography (CT) while maintaining similar noise levels in the reconstructed image. The effects of image quality and noise texture were assessed at all implementation levels of ASiR Trade-Mark-Sign . Empirically derived dose reduction limits were established for ASiR Trade-Mark-Sign for imaging of the trunk for a pediatric oncology population ranging from 1 yr old through adolescence/adulthood. Methods: Image quality was assessed using metrics established by the American College of Radiology (ACR) CT accreditation program. Each image quality metric was tested using the ACR CT phantom with 0%-100% ASiR Trade-Mark-Sign blended with filtered back projection (FBP) reconstructed images. Additionally, the noise power spectrum (NPS) was calculated for three common reconstruction filters of the trunk. The empirically derived limitations on ASiR Trade-Mark-Sign implementation for dose reduction were assessed using (1, 5, 10) yr old and adolescent/adult anthropomorphic phantoms. To assess dose reduction limits, the phantoms were scanned in increments of increased noise index (decrementing mA using automatic tube current modulation) balanced with ASiR Trade-Mark-Sign reconstruction to maintain noise equivalence of the 0% ASiR Trade-Mark-Sign image. Results: The ASiR Trade-Mark-Sign algorithm did not produce any unfavorable effects on image quality as assessed by ACR criteria. Conversely, low-contrast resolution was found to improve due to the reduction of noise in the reconstructed images. NPS calculations demonstrated that images with lower frequency noise had lower noise variance and coarser graininess at progressively higher percentages of ASiR Trade-Mark-Sign reconstruction; and in spite of the similar magnitudes of noise, the image reconstructed with 50% or more ASiR Trade-Mark-Sign presented a more

  11. Death, bereavement and traumatic loss in Israel: a historical and cultural perspective.

    Science.gov (United States)

    Witztum, E; Malkinson, R; Rubin, S S

    2001-01-01

    In the present article, we focus on the experience of bereavement and traumatic loss in Israel and examine the main influences that continue to shape them. For the Jewish population the main features are: religious aspects stemming from Jewish tradition and its variants; the secular and contemporary traditions, the ethos of the Israeli state, and the influence of the struggle to reestablish the Jewish people in its homeland. In an increasingly multicultural society, significant changes are occurring. A series of vignettes of grief and mourning illustrate current issues and practices among religious, secular, kibbutz, Russian and Ethiopian segments of society. The remainder of the article discusses emerging patterns of response to bereavement that are socially constructed and historically situated. We follow the variations in these patterns, from shifting forms of memorialization on the collective level to changes in expressive mood on the individual level, which are mediated by the cultural mosaic of the society. Mental health professionals would benefit from an understanding of the multifaceted fabric of beliefs and cultural-specific customs that shape the mourning rituals and their meanings for the bereaved.

  12. Psychological and social consequences among mothers suffering from perinatal loss: perspective from a low income country

    Directory of Open Access Journals (Sweden)

    Ali Mohammed

    2011-06-01

    Full Text Available Abstract Background In developed countries, perinatal death is known to cause major emotional and social effects on mothers. However, little is known about these effects in low income countries which bear the brunt of perinatal mortality burden. This paper reports the impact of perinatal death on psychological status and social consequences among mothers in a rural area of Bangladesh. Methods A total of 476 women including 122 women with perinatal deaths were assessed with the Edinburgh Postnatal Depression Scale (EPDS-B at 6 weeks and 6 months postpartum, and followed up for negative social consequences at 6 months postpartum. Trained female interviewers carried out structured interviews at women's home. Results Overall 43% (95% CI: 33.7-51.8% of women with a perinatal loss at 6 weeks postpartum were depressed compared to 17% (95% CI: 13.7-21.9% with healthy babies (p = Conclusions This study highlights the greatly increased vulnerability of women with perinatal death to experience negative psychological and social consequences. There is an urgent need to develop appropriate mental health care services for mothers with perinatal deaths in Bangladesh, including interventions to develop positive family support.

  13. Psychological and social consequences among mothers suffering from perinatal loss: perspective from a low income country.

    Science.gov (United States)

    Gausia, Kaniz; Moran, Allisyn C; Ali, Mohammed; Ryder, David; Fisher, Colleen; Koblinsky, Marge

    2011-06-09

    In developed countries, perinatal death is known to cause major emotional and social effects on mothers. However, little is known about these effects in low income countries which bear the brunt of perinatal mortality burden. This paper reports the impact of perinatal death on psychological status and social consequences among mothers in a rural area of Bangladesh. A total of 476 women including 122 women with perinatal deaths were assessed with the Edinburgh Postnatal Depression Scale (EPDS-B) at 6 weeks and 6 months postpartum, and followed up for negative social consequences at 6 months postpartum. Trained female interviewers carried out structured interviews at women's home. Overall 43% (95% CI: 33.7-51.8%) of women with a perinatal loss at 6 weeks postpartum were depressed compared to 17% (95% CI: 13.7-21.9%) with healthy babies (p = death to experience negative psychological and social consequences. There is an urgent need to develop appropriate mental health care services for mothers with perinatal deaths in Bangladesh, including interventions to develop positive family support.

  14. Optimizing the District Heating Primary Network from the Perspective of Economic-Specific Pressure Loss

    Directory of Open Access Journals (Sweden)

    Haichao Wang

    2017-07-01

    Full Text Available A district heating (DH system is one of the most important components of infrastructures in cold areas. Proper DH network design should balance the initial investment and the heat distribution cost of the DH network. Currently, this design is often based on a recommended value for specific pressure loss (R = ∆P/L in the main lines. This will result in a feasible network design, but probably not be optimal in most cases. The paper develops a novel optimization model to facilitate the design by considering the initial investment in the pipes and the heat distribution costs. The model will generate all possible network scenarios consisting of different series of diameters for each pipe in the flow direction of the network. Then, the annuity on the initial investment, the heat distribution cost, and the total annual cost will be calculated for each network scenario, taking into account the uncertainties of the material prices and the yearly operating time levels. The model is applied to a sample DH network and the results indicate that the model works quite well, clearly identifying the optimal network design and demonstrating that the heat distribution cost is more important than the initial investment in DH network design.

  15. Additional Energy Losses from Asymmetric and Non-Sinusoidal Current in an Electrical Facility and Methods of their Reduction

    OpenAIRE

    Tarasov, Evgeny Vladimirovich; Bulyga, Leonid Leonidovich; Ushakov, Vasily Yakovlevich; Kharlov, Nikolay Nikolaevich

    2015-01-01

    Influence of the asymmetry and higher harmonics of current on the operation of an electrical facility is analyzed. The level of additional losses from the asymmetric and non-sinusoidal currents is evaluated for a 110 kV electrical network in the Siberian Region of the Russian Federation. Methods for reducing the additional energy losses in the electrical facility are suggested.

  16. Reduction of eddy current losses around bushing holes on the top-plate of a high efficient transformer

    Directory of Open Access Journals (Sweden)

    Mehmet Aytaç ÇINAR

    2017-08-01

    Full Text Available Low voltage winding leads cause local eddy current losses in top-plate of the transformer tank. In this paper, this loss component which also causes local hot spots is investigated. Top-plate design is modified using stainless steel non-magnetic material, around the low voltage bushing holes. Manufacturing issues and cost as well as power losses are considered as main criteria during modification study. Magnetic flux distributions and eddy current losses are analysed and compared for different designs. Comparisons are based on 3D finite element simulations and experimental studies. Obtained results show that, insertion of single I-shaped stainless steel plate reduces eddy current losses around low voltage bushing holes to nearly zero.

  17. Mapping wetland loss and restoration potential in Flanders (Belgium: an ecosystem service perspective

    Directory of Open Access Journals (Sweden)

    Kris Decleer

    2016-12-01

    Full Text Available With the case of Flanders (northern part of Belgium we present an integrated approach to calculate accurate losses of wetlands, potentials for restoration, and their ecosystem services supplies and illustrate how these insights can be used to evaluate and support policy making. Flanders lost about 75% of its wetland habitats in the past 50-60 years, with currently only 68,000 ha remaining, often in a more or less degraded state. For five different wetland categories (excluding open waters we calculated that restoration of lost wetland is still possible for an additional total area of about 147,000 ha, assuming that, with time and appropriate measures and techniques, the necessary biophysical and ecological conditions can more or less be restored or created. Wetland restoration opportunities were mapped according to an open and forested landscape scenario. Despite the fact that for 49,000 ha wetland restoration is justifiable by the actual presence of an appropriate spatial planning and/or protection status, the official Flemish nature policy only foresees 7,400 to 10,600 ha of additional wetland (open waters excluded by 2050. The benefits of a more ambitious wetland restoration action program are underpinned by an explorative and quantified analysis of ecosystem service supply for each of the two scenarios, showing that the strongly increased supply of several important regulating and cultural ecosystem services might outweigh the decrease of food production, especially if extensive farming on temporary wet soils remains possible. Finally, we discuss the challenges of wetland restoration policies for biodiversity conservation and climate change.

  18. Early weight loss predicts the reduction of obesity in men with erectile dysfunction and hypogonadism undergoing long-term testosterone replacement therapy.

    Science.gov (United States)

    Salman, Mahmoud; Yassin, Dany-Jan; Shoukfeh, Huda; Nettleship, Joanne Elisabeth; Yassin, Aksam

    2017-03-01

    We and others have previously shown that testosterone replacement therapy (TRT) results in sustained weight loss in the majority of middle-aged hypogonadal men. Previously, however, a small proportion failed to lose at least 5% of their baseline weight. The reason for this is not yet understood. In the present study, we sought to identify early indicators that may predict successful long-term weight loss, defined as a reduction of at least 5% of total body weight relative to baseline weight (T0), in men with hypogonadism undergoing TRT. Eight parameters measured were assessed as potential predictors of sustained weight loss: loss of 3% or more of baseline weight after 1 year of TU treatment, severe hypogonadism, BMI, waist circumference, International Prostate Symptom Score (IPSS), glycated hemoglobin (HbA 1C ), age and use of vardenafil. Among the eight measured parameters, three factors were significantly associated with sustained weight loss over the entire period of TU treatment: (1) a loss of 3% of the baseline body weight after 1 year of TRT; (2) baseline BMI over 30; and (3) a waist circumference >102 cm. Age was not a predictor of weight loss.

  19. The public perspective of carbon capture and storage for CO2 emission reductions in China

    International Nuclear Information System (INIS)

    Duan Hongxia

    2010-01-01

    To explore public awareness of carbon capture and storage (CCS), attitudes towards the use of CCS and the determinants of CCS acceptance in China, a study was conducted in July 2009 based on face-to-face interviews with participants across the country. The result showed that the awareness of CCS was low among the surveyed public in China, compared to other clean energy technologies. Respondents indicated a slightly supportive attitude towards the use of CCS as an alternative technology to CO 2 emission reductions. The regression model revealed that in addition to CCS knowledge, respondents' understanding of the characteristics of CCS, such as the maturity of the technology, risks, capability of CO2 emission reductions, and CCS policy were all significant factors in predicting the acceptance of CCS. The findings suggest that integrating public education and communication into CCS development policy would be an effective strategy to overcome the barrier of low public acceptance.

  20. Progress and Perspective of Electrocatalytic CO2 Reduction for Renewable Carbonaceous Fuels and Chemicals.

    Science.gov (United States)

    Zhang, Wenjun; Hu, Yi; Ma, Lianbo; Zhu, Guoyin; Wang, Yanrong; Xue, Xiaolan; Chen, Renpeng; Yang, Songyuan; Jin, Zhong

    2018-01-01

    The worldwide unrestrained emission of carbon dioxide (CO 2 ) has caused serious environmental pollution and climate change issues. For the sustainable development of human civilization, it is very desirable to convert CO 2 to renewable fuels through clean and economical chemical processes. Recently, electrocatalytic CO 2 conversion is regarded as a prospective pathway for the recycling of carbon resource and the generation of sustainable fuels. In this review, recent research advances in electrocatalytic CO 2 reduction are summarized from both experimental and theoretical aspects. The referred electrocatalysts are divided into different classes, including metal-organic complexes, metals, metal alloys, inorganic metal compounds and carbon-based metal-free nanomaterials. Moreover, the selective formation processes of different reductive products, such as formic acid/formate (HCOOH/HCOO - ), monoxide carbon (CO), formaldehyde (HCHO), methane (CH 4 ), ethylene (C 2 H 4 ), methanol (CH 3 OH), ethanol (CH 3 CH 2 OH), etc. are introduced in detail, respectively. Owing to the limited energy efficiency, unmanageable selectivity, low stability, and indeterminate mechanisms of electrocatalytic CO 2 reduction, there are still many tough challenges need to be addressed. In view of this, the current research trends to overcome these obstacles in CO 2 electroreduction field are summarized. We expect that this review will provide new insights into the further technique development and practical applications of CO 2 electroreduction.

  1. Up and down the sanitation ladder: Harmonizing the treatment and multiple-barrier perspectives on risk reduction in wastewater irrigated agriculture

    DEFF Research Database (Denmark)

    Keraita, Bernard; Drechsel, P.; Konradsen, Flemming

    2010-01-01

    This paper discusses two prominent perspectives in the debate on risk reduction in wastewater irrigation; reliance on conventional wastewater treatment and the multiple-barrier approach. The treatment perspective is based on water-quality standards for wastewater irrigation with treatment...... considered the ultimate risk reductionmeasure. The somewhat broader multiple-barrier perspective supports the use of a combination of pre-farm, on-farm and postfarm barriers, including, where possible, wastewater treatment, to meet required health targets. The discussion in this paper shows that each...

  2. Harm reduction interventions in HIV care: a qualitative exploration of patient and provider perspectives

    Directory of Open Access Journals (Sweden)

    Suzanne Carlberg-Racich

    2016-04-01

    Full Text Available Background. A culture of stringent drug policy, one-size-fits-all treatment approaches, and drug-related stigma has clouded clinical HIV practice in the United States. The result is a series of missed opportunities in the HIV care environment. An approach which may address the broken relationship between patient and provider is harm reduction—which removes judgment and operates at the patient’s stage of readiness. Harm reduction is not a routine part of care; rather, it exists outside clinic walls, exacerbating the divide between compassionate, stigma-free services and the medical system. Methods. Qualitative, phenomenological, semi-structured, individual interviews with patients and providers were conducted in three publicly-funded clinics in Chicago, located in areas of high HIV prevalence and drug use and serving African-American patients (N = 38. A deductive thematic analysis guided the process, including: the creation of an index code list, transcription and verification of interviews, manual coding, notation of emerging themes and refinement of code definitions, two more rounds of coding within AtlasTi, calculation of Cohen’s Kappa for interrater reliability, queries of major codes and analysis of additional common themes. Results. Thematic analysis of findings indicated that the majority of patients felt receptive to harm reduction interventions (safer injection counseling, safer stimulant use counseling, overdose prevention information, supply provision from their provider, and expressed anticipated gratitude for harm reduction information and/or supplies within the HIV care visit, although some were reluctant to talk openly about their drug use. Provider results were mixed, with more receptivity reported by advanced practice nurses, and more barriers cited by physicians. Notable barriers included: role-perceptions, limited time, inadequate training, and the patients themselves. Discussion. Patients are willing to receive harm

  3. Study of Power Loss Reduction in SEPR Converters for Induction Heating through Implementation of SiC Based Semiconductor Switches

    Directory of Open Access Journals (Sweden)

    Angel Marinov

    2014-08-01

    Full Text Available This paper presents a power loss analysis for a Single Ended Parallel Resonance (SEPR Converter used for induction heating. The analysis includes a comparison of the losses in the electronic switch when the circuit is realized using a conventional Silicon (Si based IGBT or when using Silicon Carbide (SiC based MOSFET. The analysis includes modelling and simulation as well as experimental verification through power loss and heat dissipation measurement. The presented results can be used as a base of comparison between the switches and can be a starting point for efficiency based design of those types of converters.

  4. Whey protein and essential amino acids promote the reduction of adipose tissue and increased muscle protein synthesis during caloric restriction-induced weight loss in elderly, obese individuals

    Directory of Open Access Journals (Sweden)

    Coker Robert H

    2012-12-01

    Full Text Available Abstract Background Excess adipose tissue and sarcopenia presents a multifaceted clinical challenge that promotes morbidity and mortality in the obese, elderly population. Unfortunately, the mortality risks of muscle loss may outweigh the potential benefits of weight loss in the elderly. We have previously demonstrated the effectiveness of whey protein and essential amino acids towards the preservation of lean tissue, even under the conditions of strict bedrest in the elderly. Methods In the context of caloric restriction-based weight loss, we hypothesized that a similar formulation given as a meal replacement (EAAMR would foster the retention of lean tissue through an increase in the skeletal muscle fractional synthesis rate (FSR. We also proposed that EAAMR would promote the preferential loss of adipose tissue through the increased energy cost of skeletal muscle FSR. We recruited and randomized 12 elderly individuals to an 8 week, caloric restriction diet utilizing equivalent caloric meal replacements (800 kcal/day: 1 EAAMR or a 2 competitive meal replacement (CMR in conjunction with 400 kcal of solid food that totaled 1200 kcal/day designed to induce 7% weight loss. Combined with weekly measurements of total body weight and body composition, we also measured the acute change in the skeletal muscle FSR to EAAMR and CMR. Results By design, both groups lost ~7% of total body weight. While EAAMR did not promote a significant preservation of lean tissue, the reduction in adipose tissue was greater in EAAMR compared to CMR. Interestingly, these results corresponded to an increase in the acute skeletal muscle protein FSR. Conclusion The provision of EAAMR during caloric restriction-induced weight loss promotes the preferential reduction of adipose tissue and the modest loss of lean tissue in the elderly population.

  5. Additional Energy Losses from Asymmetric and Non-Sinusoidal Current in an Electrical Facility and Methods of their Reduction

    Directory of Open Access Journals (Sweden)

    Tarasov Evgeniy V.

    2015-01-01

    Full Text Available Influence of the asymmetry and higher harmonics of current on the operation of an electrical facility is analyzed. The level of additional losses from the asymmetric and non-sinusoidal currents is evaluated for a 110 kV electrical network in the Siberian Region of the Russian Federation. Methods for reducing the additional energy losses in the electrical facility are suggested.

  6. Passive technologies for future large-scale photonic integrated circuits on silicon: polarization handling, light non-reciprocity and loss reduction

    Directory of Open Access Journals (Sweden)

    Daoxin Dai

    2012-03-01

    Full Text Available Silicon-based large-scale photonic integrated circuits are becoming important, due to the need for higher complexity and lower cost for optical transmitters, receivers and optical buffers. In this paper, passive technologies for large-scale photonic integrated circuits are described, including polarization handling, light non-reciprocity and loss reduction. The design rule for polarization beam splitters based on asymmetrical directional couplers is summarized and several novel designs for ultra-short polarization beam splitters are reviewed. A novel concept for realizing a polarization splitter–rotator is presented with a very simple fabrication process. Realization of silicon-based light non-reciprocity devices (e.g., optical isolator, which is very important for transmitters to avoid sensitivity to reflections, is also demonstrated with the help of magneto-optical material by the bonding technology. Low-loss waveguides are another important technology for large-scale photonic integrated circuits. Ultra-low loss optical waveguides are achieved by designing a Si3N4 core with a very high aspect ratio. The loss is reduced further to <0.1 dB m−1 with an improved fabrication process incorporating a high-quality thermal oxide upper cladding by means of wafer bonding. With the developed ultra-low loss Si3N4 optical waveguides, some devices are also demonstrated, including ultra-high-Q ring resonators, low-loss arrayed-waveguide grating (demultiplexers, and high-extinction-ratio polarizers.

  7. Considerations on reduction of risk from anticipated transients without scram in a regulatory perspective

    International Nuclear Information System (INIS)

    Ahn, S. H.; Oh, D. Y.; Kim, I. K.; Lee, S. H.

    2002-01-01

    ATWS (Anticipated Transients Without Scram) are anticipated operational occurrences accompanied by the failure of the reactor trip portion of the reactor trip system. ATWS accidents are an cause of concern because under certain postulated conditions they could lead to significant core damage including core melt and to the large release of radioactivity to the environment. In this study, considerations on reduction of risk from ATWS were discussed with examination of the technical background of 10CFR 50.62. Considering the recent trends of the extended core cycle and the power uprating, it is recognized that the moderator temperature coefficient can become less negative than to suppress the RCS overpressure followed by ATWS. Because the negative reactivity feedback is one inherent level of multiple defenses, the effect against the RCS overpressure needs to be assessed in detail

  8. Reduction technique of drop voltage and power losses to improve power quality using ETAP Power Station simulation model

    Science.gov (United States)

    Satrio, Reza Indra; Subiyanto

    2018-03-01

    The effect of electric loads growth emerged direct impact in power systems distribution. Drop voltage and power losses one of the important things in power systems distribution. This paper presents modelling approach used to restructrure electrical network configuration, reduce drop voltage, reduce power losses and add new distribution transformer to enhance reliability of power systems distribution. Restructrure electrical network was aimed to analyse and investigate electric loads of a distribution transformer. Measurement of real voltage and real current were finished two times for each consumer, that were morning period and night period or when peak load. Design and simulation were conduct by using ETAP Power Station Software. Based on result of simulation and real measurement precentage of drop voltage and total power losses were mismatch with SPLN (Standard PLN) 72:1987. After added a new distribution transformer and restructrured electricity network configuration, the result of simulation could reduce drop voltage from 1.3 % - 31.3 % to 8.1 % - 9.6 % and power losses from 646.7 watt to 233.29 watt. Result showed, restructrure electricity network configuration and added new distribution transformer can be applied as an effective method to reduce drop voltage and reduce power losses.

  9. Weight reduction, energy loss and gaseous emissions for different collection systems for food waste from households; Viktreducering, energifoerlust och gasemissioner vid olika insamlingssystem av matavfall fraan hushaall

    Energy Technology Data Exchange (ETDEWEB)

    Ternald, Olle [and others

    2010-09-15

    This project investigates the weight reduction of biodegradable household waste for different types of collections systems. The report is based on empirical experiments simulating the path taken by biodegradable waste through the different systems, from kitchen to final treatment. Data from the empirical experiments have been coordinated with existing data covering the quantities of bio waste collection received by final treatment facilities. This project has resulted in updated data, which reflects the quantities of the biodegradable waste generated at household level. Through this data, it has been possible to calculate the effectiveness of the different systems for collecting biodegradable waste, including their effectiveness as a source for biogas and soil conditioner. The results regarding waste weight reduction show that systems that use paper bags give a substantial weight reduction in both the kitchen (12%) as well as in the garbage disposal container, resulting in an average total weight reduction of 27%. For the bio-plastic bag, there is a small, measurable weight reduction of 7% in the kitchen. One-family household containers also show a reduction but for multiple households contains (typically used for apartment blocks) the reduction was much smaller. The average total weight reduction for bio-plastic systems was 10%. The corresponding value for total weight reduction for plastic bags in an optical system was 2%-4%, with an average of 2%. The largest share of the reduction consists of water, but some carbon is also emitted. Another conclusion of the report it that a larger share of the biodegradable waste generated by the Swedish households is collected than previously assumed. The data for generated (collected) biodegradable waste material shows higher levels and larger differences between the different collection systems than the data for the received (weighted) material at the treatment facilities. The data shows the effectiveness of each system and

  10. How three countries in the Americas are fortifying dietary salt reduction: a north and south perspective.

    Science.gov (United States)

    Legowski, Barbara; Legetic, Branka

    2011-09-01

    A chronic disease/risk factor prevention framework with three policy environments--communications, physical and economic--was used to organize population level interventions that address the "over consumption of dietary salt", a key risk factor for cardiovascular diseases. The framework was then used to map the population based strategies to reduce dietary salt consumption being applied in three countries in the Americas--Argentina, Canada and Chile--each with a history of multi-sector approaches to deal with the risk factors for chronic disease, offering a north versus south perspective. Results show that in all three countries policy instruments are concentrated in the communications environment, e.g., media and education campaigns and/or regulations for standardized information on the salt or sodium content of packaged food products. Notable gaps are the requirement for nutrient information on meals and food items prepared by food establishments and restrictions on advertising and marketing of foods to children. In the physical environment, referring to the sodium levels in commercially prepared foods and meals available on the market, voluntary reformulation of food products is underway at this time in the three countries. Argentina and Chile began with bread and have gradually added other food categories; Canada at the outset is addressing all food categories where products have added salt. Argentina alone is at this point actively approaching regulations to limit the salt content of food, preferring this over ongoing monitoring of voluntary targets. No government in the three counties has yet considered action in the economic environment, a complex area where the research on and initiatives to limit or disadvantage energy-dense food products to address obesity may also capture foods that are highly salted. In the meantime, with recent research estimating substantially higher gains in population health from government legislation to limit salt in foods

  11. Provincial Carbon Emissions Reduction Allocation Plan in China Based on Consumption Perspective

    Directory of Open Access Journals (Sweden)

    Xuecheng Wang

    2018-04-01

    Full Text Available China is a country with substantial differences in economic development, energy consumption mix, resources, and technologies, as well as the development path at the provincial level. Therefore, China’s provinces have different potential and degrees of difficulty to carry out carbon emission reduction (CER requirements. In addition, interprovincial trade, with a large amount of embodied carbon emissions, has become the fastest growing driver of China’s total carbon emissions. A reasonable CER allocation plan is, therefore, crucial for realizing the commitment that China announced in the Paris Agreement. How to determine a fair way to allocate provincial CER duties has become a significant challenge for both policy-makers and researchers. In this paper, ecological network analysis (ENA, combined with a multi-regional input-output model (MRIO, is adopted to build an ecological network of embodied emissions across 30 provinces. Then, by using flow analysis and utility analysis based on the ENA model, the specific relationships among different provinces were determined, and the amount of responsibility that a certain province should take quantified, with respect to the embodied carbon emission (ECE flows from interprovincial trade. As a result, we suggest a new CER allocation plan, based on the detailed data of interprovincial relationships and ECE flows.

  12. Light-cone reduction vs. TsT transformations: a fluid dynamics perspective

    Science.gov (United States)

    Dutta, Suvankar; Krishna, Hare

    2018-05-01

    We compute constitutive relations for a charged (2+1) dimensional Schrödinger fluid up to first order in derivative expansion, using holographic techniques. Starting with a locally boosted, asymptotically AdS, 4 + 1 dimensional charged black brane geometry, we uplift that to ten dimensions and perform TsT transformations to obtain an effective five dimensional local black brane solution with asymptotically Schrödinger isometries. By suitably implementing the holographic techniques, we compute the constitutive relations for the effective fluid living on the boundary of this space-time and extract first order transport coefficients from these relations. Schrödinger fluid can also be obtained by reducing a charged relativistic conformal fluid over light-cone. It turns out that both the approaches result the same system at the end. Fluid obtained by light-cone reduction satisfies a restricted class of thermodynamics. Here, we see that the charged fluid obtained holographically also belongs to the same restricted class.

  13. Parent Perspectives of Applying Mindfulness-Based Stress Reduction Strategies to Special Education.

    Science.gov (United States)

    Burke, Meghan M; Chan, Neilson; Neece, Cameron L

    2017-06-01

    Parents of children with (versus without) intellectual and developmental disabilities report greater stress; such stress may be exacerbated by dissatisfaction with school services, poor parent-school partnerships, and the need for parent advocacy. Increasingly, mindfulness interventions have been used to reduce parent stress. However, it is unclear whether parents apply mindfulness strategies during the special education process to reduce school-related stress. To investigate whether mindfulness may reduce school-related stress, interviews were conducted with 26 parents of children with intellectual and developmental disabilities who completed a mindfulness-based stress reduction intervention. Participants were asked about their stress during meetings with the school, use of mindfulness strategies in communicating with the school, and the impact of such strategies. The majority of parent participants reported: special education meetings were stressful; they used mindfulness strategies during IEP meetings; and such strategies affected parents' perceptions of improvements in personal well-being, advocacy, family-school relationships, and access to services for their children. Implications for future research, policy, and practice are discussed.

  14. A NEW GIS NITROGEN TRADING TOOL CONCEPT FOR CONSERVATION AND REDUCTION OF REACTIVE NITROGEN LOSSES TO THE ENVIRONMENT

    Science.gov (United States)

    Nitrogen inputs to agricultural systems are important for their sustainability. However, when N inputs are unnecessarily high, the excess can contribute to greater agricultural N losses that impact air, surface water and groundwater quality. It is paramount to reduce off-site transport of N by using...

  15. Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction123

    OpenAIRE

    Browning, Jeffrey D; Baker, Jonathan A; Rogers, Thomas; Davis, Jeannie; Satapati, Santhosh; Burgess, Shawn C

    2011-01-01

    Background: Individuals with nonalcoholic fatty liver disease (NAFLD) have excess intrahepatic triglycerides. This is due, in part, to increased hepatic synthesis of fat from carbohydrates via lipogenesis. Although weight loss is currently recommended to treat NAFLD, little attention has been given to dietary carbohydrate restriction.

  16. Risk Factors for Loss to Follow-Up among People Who Inject Drugs in a Risk Reduction Program at Karachi, Pakistan. A Case-Cohort Study.

    Directory of Open Access Journals (Sweden)

    Rab Nawaz Samo

    Full Text Available Retention of male people who inject drugs (PWIDs is a major challenge for harm reduction programs that include sterile needle/syringe exchange in resource-limited settings like Pakistan. We assessed the risk factors for loss to follow-up among male PWIDs enrolled in a risk reduction program in Karachi, Pakistan.We conducted a prospective cohort study among 636 HIV-uninfected male PWIDs enrolled during March-June 2009 in a harm reduction program for the estimation of incidence rate. At 24 months post-enrollment, clients who had dropped out of the program were defined as lost to follow-up and included as cases for case-cohort study.The median age of the participants was 29 years (interquartile range: 23-36. Active outreach accounted for 76% (483/636 of cohort recruits. Loss to follow-up at 24 months was 25.5% (162/636. In multivariable logistic regression, younger age (AOR: 0.97, 95% CI: 0.92-0.99, p = 0.028, clients from other provinces than Sindh (AOR: 1.49, 95% CI: 1.01-2.22, p = 0.046, having no formal education (AOR: 3.44, 95% CI: 2.35-4.90, p<0.001, a history of incarceration (AOR: 1.68, 95% CI: 1.14-2.46, p<0.008, and being homeless (AOR: 1.47, 95% CI: 1.00-2.19, p<0.049 were associated with loss to follow-up.Our cohort retained 74.5% of male PWIDs in Karachi for 24 months. Its loss to follow up rate suggested substantial ongoing programmatic challenges. Programmatic enhancements are needed for the highest risk male PWIDs, i.e., younger men, men not from Sindh Province, men who are poorly educated, formerly incarcerated, and/or homeless.

  17. Advanced numerical methods for uncertainty reduction when predicting heat exchanger dynamic stability limits: Review and perspectives

    International Nuclear Information System (INIS)

    Longatte, E.; Baj, F.; Hoarau, Y.; Braza, M.; Ruiz, D.; Canteneur, C.

    2013-01-01

    Highlights: ► Proposal of hybrid computational methods for investigating dynamical system stability. ► Modeling turbulence disequilibrium due to interaction with moving solid boundaries. ► Providing computational procedure for large size system solution approximation through model reduction. -- Abstract: This article proposes a review of recent and current developments in the modeling and advanced numerical methods used to simulate large-size systems involving multi-physics in the field of mechanics. It addresses the complex issue of stability analysis of dynamical systems submitted to external turbulent flows and aims to establish accurate stability maps applicable to heat exchanger design. The purpose is to provide dimensionless stability limit modeling that is suitable for a variety of configurations and is as accurate as possible in spite of the large scale of the systems to be considered. The challenge lies in predicting local effects that may impact global systems. A combination of several strategies that are suited concurrently to multi-physics, multi-scale and large-size system computation is therefore required. Based on empirical concepts, the heuristic models currently used in the framework of standard stability analysis suffer from a lack of predictive capabilities. On the other hand, numerical approaches based on fully-coupled fluid–solid dynamics system computation remain expensive due to the multi-physics patterns of physics and the large number of degrees of freedom involved. In this context, since experimentation cannot be achieved and numerical simulation is unavoidable but prohibitive, a hybrid strategy is proposed in order to take advantage of both numerical local solutions and empirical global solutions

  18. Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction

    Directory of Open Access Journals (Sweden)

    Gerlach N

    2016-09-01

    Full Text Available Nicole Gerlach,1,* Matthias Mentel,2,* Tim Köhler,2 Benjamin Tuchscherer,2 Birgit Garbe,1 Jasmina Ülker,1 Hagen Tronnier,1 Ulrike Heinrich,1 Mike Farwick2 1DermaTronnier GmbH & Co. KG, Institute for Experimental Dermatology, Witten/Herdecke University, Witten, 2Evonik Nutrition & Care GmbH, Essen, Germany *These authors contributed equally to this work Abstract: Sphingolipids are well known to promote keratinocyte differentiation and to induce ceramide production. In addition, they show anti-inflammatory and antimicrobial activities. Thus, the aim of this study is to investigate the potential effect of sphinganine on prolonging the hair anagen rate and improving the overall hair quality and scalp health. The inhibitory potential of sphinganine toward 5-α-reductase was studied using an in vitro assay. The stimulation of the antimicrobial peptide HBD2 by sphinganine was measured by real-time polymerase chain reaction and immunostaining. Sphinganine bioavailability was studied ex vivo using a pig skin model. A placebo-controlled, double-blind study was designed to evaluate the efficacy of sphinganine on hair loss and hair/scalp quality in vivo. In vitro results showed that sphinganine is a potent inhibitor of 5-α-reductase type I that prevents the conversion of testosterone to dihydrotestosterone, a key factor of androgenetic male baldness. In vivo results demonstrated efficacy in reducing non-illness-related hair loss among males. In terms of expert rating, all hair quality and scalp parameters improved after application of sphinganine. Improved scalp health might be linked to the observed increase of the antimicrobial peptide HBD2. Thus, sphinganine is well suited as a topical alternative for the improvement of scalp health and hair quality and anti-hair loss application. Keywords: sphinganine, 5-α-reductase inhibition, HBD2, hair loss, anagen rate, TrichoScan®

  19. Reduction of uncertainties on the components of the reactivity loss per cycle, the Balzac program on Masurca

    International Nuclear Information System (INIS)

    D'Angelo, A.; Karouby-Cohen, N.; Palmiotti, G.; Rimpault, G.; Salvatores, M.; Soule, R.

    1984-10-01

    The uncertainties on the reactivity loss per cycle are mainly due to the uncertainties on the heavy isotopes component. This paper, presents an experimental program for reducing these uncertainties. This program is based on a range of fuel irradiation experiments on power reactor and a range of isotopic variations experiments in the critical facility MASURCA consisting basically of subcritical measurements, from a reference configuration and in several different spectra

  20. Two year reduction in sleep apnea symptoms and associated diabetes incidence after weight loss in severe obesity.

    Science.gov (United States)

    Grunstein, Ronald R; Stenlöf, Kaj; Hedner, Jan A; Peltonen, Markku; Karason, Kristjan; Sjöström, Lars

    2007-06-01

    To evaluate the effect of bariatric surgery on sleep apnea symptoms and obesity-associated morbidity in patients with severe obesity. Prospective study. University hospitals and community centers in Sweden. We investigated the influence of weight loss surgery (n=1729) on sleep apnea symptoms and obesity-related morbidity using a conservatively treated group (n=1748) as a control. Baseline BMI in surgical group (42.2+/-4.4 kg/m(2)) and control group (40.1+/-4.6 kg/m(2)) changed -9.7+/-5 kg/m(2) and 0+/-3 kg/m(2), respectively, at 2-year follow-up. In the surgery group, there was a marked improvement in all obstructive sleep apnea (OSA) symptoms compared with the control group (P sleep apnea symptoms at 2 years. Despite adjustment for weight change and baseline central obesity, subjects reporting loss of OSA symptoms had a lower 2-year incidence of diabetes and hypertriglyceridemia. Improvement in OSA in patients losing weight may provide health benefits in addition to weight loss alone.

  1. Significant reduction of saturation magnetization and microwave-reflection loss in barium-natural ferrite via Nd3+ substitution

    Science.gov (United States)

    Widanarto, W.; Ardenti, E.; Ghoshal, S. K.; Kurniawan, C.; Effendi, M.; Cahyanto, W. T.

    2018-06-01

    To minimize the signal degradation, many electronic devices require efficient microwave absorbers with very low reflection-losses within the X-band. We prepared a series of trivalent neodymium-ion (Nd3+) substituted barium-natural ferrite using a modified solid-state reaction method. The effect of the Nd3+-ion content on the structure, surface morphology, magnetic properties, and microwave reflection loss was studied. The composites were characterized using X-ray diffraction, a vibrating sample magnetometer, scanning electron microscopy, and a vector network analyzer. The XRD patterns of the sample without Nd3+ reveal the presence of BaFe12O19 (hexagonal) and BaFe2O4 (rhombohedral) phases. Furthermore, a new hexagonal crystal phase of Ba6Nd2Fe4O15 appeared after substituting Nd3+. The average size of the prepared barium-natural ferrite particles was estimated to be between 0.4 and 0.8 μm. Both saturation magnetization and microwave reflection losses of these barium-ferrites were significantly reduced by increasing the Nd3+ content.

  2. Evidence of "hidden hearing loss" following noise exposures that produce robust TTS and ABR wave-I amplitude reductions.

    Science.gov (United States)

    Lobarinas, Edward; Spankovich, Christopher; Le Prell, Colleen G

    2017-06-01

    In animals, noise exposures that produce robust temporary threshold shifts (TTS) can produce immediate damage to afferent synapses and long-term degeneration of low spontaneous rate auditory nerve fibers. This synaptopathic damage has been shown to correlate with reduced auditory brainstem response (ABR) wave-I amplitudes at suprathreshold levels. The perceptual consequences of this "synaptopathy" remain unknown but have been suggested to include compromised hearing performance in competing background noise. Here, we used a modified startle inhibition paradigm to evaluate whether noise exposures that produce robust TTS and ABR wave-I reduction but not permanent threshold shift (PTS) reduced hearing-in-noise performance. Animals exposed to 109 dB SPL octave band noise showed TTS >30 dB 24-h post noise and modest but persistent ABR wave-I reduction 2 weeks post noise despite full recovery of ABR thresholds. Hearing-in-noise performance was negatively affected by the noise exposure. However, the effect was observed only at the poorest signal to noise ratio and was frequency specific. Although TTS >30 dB 24-h post noise was a predictor of functional deficits, there was no relationship between the degree of ABR wave-I reduction and degree of functional impairment. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Comparison of Two Methods of Bolus and Infusion of Tranexamic Acid in Reduction of Blood Loss in Total Knee Arthroplasty

    OpenAIRE

    Mohammadreza Moshari; Bahman Malek; Mohammadreza Minator-Sajjadi; Maryam Vosoghian; Mastaneh Dahi; Mahshid Ghasemi; Razieh Shekari

    2018-01-01

    AbstractBackground: So far, many studies have been performed to determine the optimal dose and regimen of tranexamic acid to reduce preoperative and postoperative blood loss in primary total knee arthroplasty. In the present study, two different methods of administration (bolus and infusion), were compared.Materials and Methods: Forty patients were randomized in the two groups (A and B) of 20 patients each. All patients received 500 mg tranexamic acid before inflation of tourniquet. Group A (...

  4. A Formal Approach to the Selection by Minimum Error and Pattern Method for Sensor Data Loss Reduction in Unstable Wireless Sensor Network Communications.

    Science.gov (United States)

    Kim, Changhwa; Shin, DongHyun

    2017-05-12

    There are wireless networks in which typically communications are unsafe. Most terrestrial wireless sensor networks belong to this category of networks. Another example of an unsafe communication network is an underwater acoustic sensor network (UWASN). In UWASNs in particular, communication failures occur frequently and the failure durations can range from seconds up to a few hours, days, or even weeks. These communication failures can cause data losses significant enough to seriously damage human life or property, depending on their application areas. In this paper, we propose a framework to reduce sensor data loss during communication failures and we present a formal approach to the Selection by Minimum Error and Pattern (SMEP) method that plays the most important role for the reduction in sensor data loss under the proposed framework. The SMEP method is compared with other methods to validate its effectiveness through experiments using real-field sensor data sets. Moreover, based on our experimental results and performance comparisons, the SMEP method has been validated to be better than others in terms of the average sensor data value error rate caused by sensor data loss.

  5. Medical weight loss versus bariatric surgery: does method affect body composition and weight maintenance after 15% reduction in body weight?

    Science.gov (United States)

    Kulovitz, Michelle G; Kolkmeyer, Deborah; Conn, Carole A; Cohen, Deborah A; Ferraro, Robert T

    2014-01-01

    The aim of this study was to investigate body composition changes in fat mass (FM) to lean body mass (LBM) ratios following 15% body weight loss (WL) in both integrated medical treatment and bariatric surgery groups. Obese patients (body mass index [BMI] 46.6 ± 6.5 kg/m(2)) who underwent laparoscopic gastric bypass surgery (BS), were matched with 24 patients undergoing integrated medical and behavioral treatment (MT). The BS and MT groups were evaluated for body weight, BMI, body composition, and waist circumference (WC) at baseline and after 15% WL. Following 15% body WL, there were significant decreases in %FM and increased %LBM (P maintenance of WL at 1 y were found. For both groups, baseline FM was found to be negatively correlated with percentage of weight regained (%WR) at 1 y post-WL (r = -0.457; P = 0.007). Baseline WC and rate of WL to 15% were significant predictors of %WR only in the BS group (r = 0.713; P = 0.020). If followed closely by professionals during the first 15% body WL, patients losing 15% weight by either medical or surgical treatments can attain similar FM:LBM loss ratios and can maintain WL for 1 y. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Land-use intensification can exaggerate the reduction of functionality with increasing soil biodiversity loss in an alpine meadow on eastern Tibetan Plateau

    Science.gov (United States)

    Liu, Manqiang; Chen, Xiaoyun; Chen, Chenying; Hu, Zhengkun; Guo, Hui; Li, Junyong; Du, Guozhen; Li, Huixin; Hu, Feng

    2017-04-01

    Soil biota plays a pivotal role in ecosystem functionality which is of central importance to sustainable services such as food and fiber production. Intensive land use is associated with species loss and subsequent the related functionality loss. Currently, the claim that negligible effects of soil biodiversity loss due to high functional redundancy has been questioned in the face of intense human activities. Recent studies corroborated that soil biodiversity guaranteed functionality following perturbation. Few studies have, however, attempted to explore the intensive land use on the relationship between soil biodiversity and function particularly for the region susceptible to human perturbation and climate change. With increasing demands for livestock on the Qinghai-Tibetan Plateau, extensive fertilization is a common way to fill the gap of grass productivity in the alpine meadow. However, excess chemical fertilizer can lead to the species loss and functionality degradation. Do the fertilizer-induced changes in soil biota lead to a higher risk of functionality? We predicted that fertilization would exacerbate effects of biodiversity-loss on the reduction of functionality. Herein, a dilution-to-extinction approach was used to set up soil biodiversity loss by inoculating serially diluted soil suspension (ranging from 100 to 10-8 levels) from two long-term fertilization treatments to the sterilized soil that has never been fertilized. The two fertilization treatments represented two distinct intensification land use including the unfertilized control (NP0) and a fertilized treatment (NP120) amended with (NH4)2HPO4 annually (120 kg ha-1 yr-1) since 2002 in an alpine meadow on the eastern Qinghai-Tibetan Plateau. Soil microcosms of 2 fertilization levels crossing 8 biodiversity levels were incubated for 8 months. Then, soil community and multi-functionality parameters including carbon (C)and nutrient mineralization, plant growth and functional stability were determined

  7. Synthesis of high intrinsic loss power aqueous ferrofluids of iron oxide nanoparticles by citric acid-assisted hydrothermal-reduction route

    International Nuclear Information System (INIS)

    Behdadfar, Behshid; Kermanpur, Ahmad; Sadeghi-Aliabadi, Hojjat; Morales, Maria del Puerto; Mozaffari, Morteza

    2012-01-01

    Monodispersed aqueous ferrofluids of iron oxide nanoparticle were synthesized by hydrothermal-reduction route. They were characterized by X-ray diffraction analysis, Fourier transform infrared spectroscopy, scanning and transmission electron microscopy and dynamic light scattering. The results showed that certain concentrations of citric acid (CA) are required to obtain only magnetic iron oxides with mean particle sizes around 8 nm. CA acts as a modulator and reducing agent in iron oxide formation which controls nanoparticle size. The XRD, magnetic and heating measurements showed that the temperature and time of hydrothermal reaction can affect the magnetic properties of obtained ferrofluids. The synthesized ferrofluids were stable at pH 7. Their mean hydrodynamic size was around 80 nm with polydispersity index (PDI) of 0.158. The calculated intrinsic loss power (ILP) was 9.4 nHm 2 /kg. So this clean and cheap route is an efficient way to synthesize high ILP aqueous ferrofluids applicable in magnetic hyperthermia. - Graphical abstract: Monodispersed aqueous ferrofluids of iron oxide nanoparticles were synthesized by hydrothermal-reduction method with citric acid as reductant which is an efficient way to synthesize aqueous ferrofluids applicable in magnetic hyperthermia. Highlights: ► Aqueous iron oxide ferrofluids were synthesized by hydrothermal-reduction route. ► Citric acid acted as reducing agent and surfactant in the route. ► This is a facile, low energy and environmental friendly route. ► The aqueous iron oxide ferrofluids were monodispersed and stable at pH of 7. ► The calculated intrinsic loss power of the synthesized ferrofluids was very high.

  8. Flood loss reduction of private households due to building precautionary measures -- lessons learned from the Elbe flood in August 2002

    Directory of Open Access Journals (Sweden)

    H. Kreibich

    2005-01-01

    Full Text Available Building houses in inundation areas is always a risk, since absolute flood protection is impossible. Where settlements already exist, flood damage must be kept as small as possible. Suitable means are precautionary measures such as elevated building configuration or flood adapted use. However, data about the effects of such measures are rare, and consequently, the efficiency of different precautionary measures is unclear. To improve the knowledge about efficient precautionary measures, approximately 1200 private households, which were affected by the 2002 flood at the river Elbe and its tributaries, were interviewed about the flood damage of their buildings and contents as well as about their precautionary measures. The affected households had little flood experience, i.e. only 15% had experienced a flood before. 59% of the households stated that they did not know, that they live in a flood prone area. Thus, people were not well prepared, e.g. just 11% had used and furnished their house in a flood adapted way and only 6% had a flood adapted building structure. Building precautionary measures are mainly effective in areas with frequent small floods. But also during the extreme flood event in 2002 building measures reduced the flood loss. From the six different building precautionary measures under study, flood adapted use and adapted interior fitting were the most effective ones. They reduced the damage ratio for buildings by 46% and 53%, respectively. The damage ratio for contents was reduced by 48% due to flood adapted use and by 53% due to flood adapted interior fitting. The 2002 flood motivated a relatively large number of people to implement private precautionary measures, but still much more could be done. Hence, to further reduce flood losses, people's motivation to invest in precaution should be improved. More information campaigns and financial incentives should be issued to encourage precautionary measures.

  9. The Reduction of Ventrolateral Prefrontal Cortex Gray Matter Volume Correlates with Loss of Economic Rationality in Aging.

    Science.gov (United States)

    Chung, Hui-Kuan; Tymula, Agnieszka; Glimcher, Paul

    2017-12-06

    The population of people above 65 years old continues to grow, and there is mounting evidence that as humans age they are more likely to make errors. However, the specific effect of neuroanatomical aging on the efficiency of economic decision-making is poorly understood. We used whole-brain voxel-based morphometry analysis to determine where reduction of gray matter volume in healthy female and male adults over the age of 65 years correlates with a classic measure of economic irrationality: violations of the Generalized Axiom of Revealed Preference. All participants were functionally normal with Mini-Mental State Examination scores ranging between 26 and 30. While our elders showed the previously reported decline in rationality compared with younger subjects, chronological age per se did not correlate with rationality measures within our population of elders. Instead, reduction of gray matter density in ventrolateral prefrontal cortex correlates tightly with irrational behavior. Interestingly, using a large fMRI sample and meta-analytic tool with Neurosynth, we found that this brain area shows strong coactivation patterns with nearly all of the value-associated regions identified in previous studies. These findings point toward a neuroanatomic locus for economic rationality in the aging brain and highlight the importance of understanding both anatomy and function in the study of aging, cognition, and decision-making. SIGNIFICANCE STATEMENT Age is a crucial factor in decision-making, with older individuals making more errors in choices. Using whole-brain voxel-based morphometry analysis, we found that reduction of gray matter density in ventrolateral prefrontal cortex correlates with economic irrationality: reduced gray matter volume in this area correlates with the frequency and severity of violations of the Generalized Axiom of Revealed Preference. Furthermore, this brain area strongly coactivates with other reward-associated regions identified with Neurosynth

  10. Gain versus loss framing in adherence-promoting communication targeting patients with chronic diseases: the moderating effect of individual time perspective.

    Science.gov (United States)

    Zhao, Xiaoquan; Villagran, Melinda M; Kreps, Gary L; McHorney, Colleen

    2012-01-01

    This study investigated the joint effect of message framing and time perspective in adherence-promoting communication targeting patients with chronic diseases. Based on previous framing and time perspective research, it was hypothesized that the gain frame would show an advantage over the loss frame among future-oriented patients; for present-oriented patients, it was hypothesized that the framing effect would be relatively indistinct. In total, 1,108 currently nonadherent patients with chronic disease participated in an experiment where they were randomly assigned to either gain- or loss-framed messages addressing key beliefs underlying their nonadherence or a no-message control condition. Intention and attitude regarding future adherence as well as message perceptions were measured after message presentation. Results of this study generally supported the hypotheses. Message topics-whether the messages addressed patients' perceived need for medications or concerns about side effects-did not moderate the effect of framing or the interaction between framing and time perspective. Theoretical and practical implications are discussed.

  11. Low-fat versus low-carbohydrate weight reduction diets: effects on weight loss, insulin resistance, and cardiovascular risk: a randomized control trial.

    Science.gov (United States)

    Bradley, Una; Spence, Michelle; Courtney, C Hamish; McKinley, Michelle C; Ennis, Cieran N; McCance, David R; McEneny, Jane; Bell, Patrick M; Young, Ian S; Hunter, Steven J

    2009-12-01

    Low-fat hypocaloric diets reduce insulin resistance and prevent type 2 diabetes in those at risk. Low-carbohydrate, high-fat diets are advocated as an alternative, but reciprocal increases in dietary fat may have detrimental effects on insulin resistance and offset the benefits of weight reduction. We investigated a low-fat (20% fat, 60% carbohydrate) versus a low-carbohydrate (60% fat, 20% carbohydrate) weight reduction diet in 24 overweight/obese subjects ([mean +/- SD] BMI 33.6 +/- 3.7 kg/m(2), aged 39 +/- 10 years) in an 8-week randomized controlled trial. All food was weighed and distributed, and intake was calculated to produce a 500 kcal/day energy deficit. Insulin action was assessed by the euglycemic clamp and insulin secretion by meal tolerance test. Body composition, adipokine levels, and vascular compliance by pulse-wave analysis were also measured. Significant weight loss occurred in both groups (P loss with no difference between groups (P = 0.71). The change in overall systemic arterial stiffness was, however, significantly different between diets (P = 0.04); this reflected a significant decrease in augmentation index following the low-fat diet, compared with a nonsignificant increase within the low-carbohydrate group. This study demonstrates comparable effects on insulin resistance of low-fat and low-carbohydrate diets independent of macronutrient content. The difference in augmentation index may imply a negative effect of low-carbohydrate diets on vascular risk.

  12. Accounting for density reduction and structural loss in standing dead trees: Implications for forest biomass and carbon stock estimates in the United States

    Directory of Open Access Journals (Sweden)

    Domke Grant M

    2011-11-01

    Full Text Available Abstract Background Standing dead trees are one component of forest ecosystem dead wood carbon (C pools, whose national stock is estimated by the U.S. as required by the United Nations Framework Convention on Climate Change. Historically, standing dead tree C has been estimated as a function of live tree growing stock volume in the U.S.'s National Greenhouse Gas Inventory. Initiated in 1998, the USDA Forest Service's Forest Inventory and Analysis program (responsible for compiling the Nation's forest C estimates began consistent nationwide sampling of standing dead trees, which may now supplant previous purely model-based approaches to standing dead biomass and C stock estimation. A substantial hurdle to estimating standing dead tree biomass and C attributes is that traditional estimation procedures are based on merchantability paradigms that may not reflect density reductions or structural loss due to decomposition common in standing dead trees. The goal of this study was to incorporate standing dead tree adjustments into the current estimation procedures and assess how biomass and C stocks change at multiple spatial scales. Results Accounting for decay and structural loss in standing dead trees significantly decreased tree- and plot-level C stock estimates (and subsequent C stocks by decay class and tree component. At a regional scale, incorporating adjustment factors decreased standing dead quaking aspen biomass estimates by almost 50 percent in the Lake States and Douglas-fir estimates by more than 36 percent in the Pacific Northwest. Conclusions Substantial overestimates of standing dead tree biomass and C stocks occur when one does not account for density reductions or structural loss. Forest inventory estimation procedures that are descended from merchantability standards may need to be revised toward a more holistic approach to determining standing dead tree biomass and C attributes (i.e., attributes of tree biomass outside of sawlog

  13. Liraglutide and obesity in elderly: efficacy in fat loss and safety in order to prevent sarcopenia. A perspective case series study.

    Science.gov (United States)

    Perna, Simone; Guido, Davide; Bologna, Chiara; Solerte, Sebastiano Bruno; Guerriero, Fabio; Isu, Antonio; Rondanelli, Mariangela

    2016-12-01

    For the growing numbers of obese elderly with diabetes, the glucagon-like peptide-1 (GLP-1) receptor analogue (liraglutide) appears a safe way to promote and maintain substantial weight loss. Given this background, the aim of this study was to assess the effect of the liraglutide treatment, at doses up to 3.0 mg per day, on the body composition, focusing on sarcopenia, in overweight and obese elderly with type 2 diabetes mellitus (T2DM). A perspective study was carried out in overweight and obese T2DM patients with HbA1c equal to 7.0 % (53 mmol/mol) ~10.0 % (86), under 3-month treatment (at least) of maximal dose of metformin at stable regime, and additional liraglutide at doses up to 3.0 mg per day. Body composition markers such as skeletal muscle index (SMI), android and gynoid fat mass, and arms and legs fat free mass, was measured by dual-energy X-ray densitometry (DXA) at baseline and after 24 weeks of liraglutide treatment. Glucose control was also carried out by glucose and HbA1c. Nine subjects (male/female 6/3, mean age 68.22 ± 3.86 years, BMI 32.34 ± 4.89 kg/m 2 ) were evaluated. We noted a median decrease in BMI (-0.78 kg/m 2 ), weight (-2000 g), fat mass (-1498 g) and android fat (-0.9 %), and a increase in SMI (+0.03 kg/m 2 ) from baseline. Glycemic control also improved, with a median change HbA1c of -0.80 %. Twenty-four weeks of liraglutide treatment was associated with reductions in fat mass and android fat. In addition, in order to prevent sarcopenia, it preserved the muscular tropism.

  14. Voltage Profile Enhancement and Reduction of Real Power loss by Hybrid Biogeography Based Artificial Bee Colony algorithm

    Directory of Open Access Journals (Sweden)

    K. Lenin

    2014-04-01

    Full Text Available This paper presents Hybrid Biogeography algorithm for solving the multi-objective reactive power dispatch problem in a power system. Real Power Loss minimization and maximization of voltage stability margin are taken as the objectives. Artificial bee colony optimization (ABC is quick and forceful algorithm for global optimization. Biogeography-Based Optimization (BBO is a new-fangled biogeography inspired algorithm. It mainly utilizes the biogeography-based relocation operator to share the information among solutions. In this work, a hybrid algorithm with BBO and ABC is projected, and named as HBBABC (Hybrid Biogeography based Artificial Bee Colony Optimization, for the universal numerical optimization problem. HBBABC merge the searching behavior of ABC with that of BBO. Both the algorithms have different solution probing tendency like ABC have good exploration probing tendency while BBO have good exploitation probing tendency.  HBBABC used to solve the reactive power dispatch problem and the proposed technique has been tested in standard IEEE30 bus test system.

  15. Evolutionary transitions in symbioses: dramatic reductions in bathymetric and geographic ranges of Zoanthidea coincide with loss of symbioses with invertebrates.

    Science.gov (United States)

    Swain, Timothy D

    2010-06-01

    Two fundamental symbiosis-based trophic types are recognized among Zoanthidea (Cnidaria, Anthozoa): fixed carbon is either obtained directly from zooxanthellae photosymbionts or from environmental sources through feeding with the assistance of host-invertebrate behaviour and structure. Each trophic type is characteristic of the suborders of Zoanthidea and is associated with substantial distributional asymmetries: suborder Macrocnemina are symbionts of invertebrates and have global geographic and bathymetric distributions and suborder Brachycnemina are hosts of endosymbiotic zooxanthellae and are restricted to tropical photic zones. While exposure to solar radiation could explain the bathymetric asymmetry it does not explain the geographic asymmetry, nor is it clear why evolutionary transitions to the zooxanthellae-free state have apparently occurred within Macrocnemina but not within Brachycnemina. To better understand the transitions between symbiosis-based trophic types of Zoanthidea, a concatenated data set of nuclear and mitochondrial nucleotide sequences were used to test hypotheses of monophyly for groups defined by morphology and symbiosis, and to reconstruct the evolutionary transitions of morphological and symbiotic characters. The results indicate that the morphological characters that define Macrocnemina are plesiomorphic and the characters that define its subordinate taxa are homoplasious. Symbioses with invertebrates have ancient and recent transitions with a general pattern of stability in host associations through evolutionary time. The reduction in distribution of Zoanthidea is independent of the evolution of zooxanthellae symbiosis and consistent with hypotheses of the benefits of invertebrate symbioses, indicating that the ability to persist in most habitats may have been lost with the termination of symbioses with invertebrates.

  16. Beam loss reduction by injection painting in the 3-GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    H. Hotchi

    2012-04-01

    Full Text Available The 3-GeV rapid cycling synchrotron (RCS of the Japan Proton Accelerator Research Complex was commissioned in October 2007. Via the initial beam tuning and a series of underlying beam studies with low-intensity beams, since December 2009, we have intermittently been performing beam tuning experiments with higher-intensity beams including the injection painting technique. By optimizing the injection painting parameters, we have successfully achieved a 420 kW-equivalent output intensity at a low-level intensity loss of less than 1%. Also the corresponding numerical simulation well reproduced the observed painting parameter dependence on the beam loss, and captured a characteristic behavior of the high-intensity beam in the injection painting process. In this paper, we present the experimental results obtained in the course of the RCS beam power ramp-up, especially on the beam loss reduction achieved by employing the injection painting, together with the numerical simulation results.

  17. Weight loss has an additive effect on the proteinuria reduction of angiotensin II receptor blockers in hypertensive patients with chronic kidney disease

    Directory of Open Access Journals (Sweden)

    Shin Young Ahn

    2018-03-01

    Full Text Available Background : Weight reduction is a lifestyle intervention that has been introduced for prevention and management of chronic kidney disease (CKD. We investigate the additive anti-proteinuric effect of weight reduction on the usage of angiotensin II receptor blockers (ARBs and its potential mechanisms in hypertensive CKD patients. Methods : This study is a subanalysis of data from an open-label, randomized, controlled clinical trial. Among the 235 participants, 227 were assigned to subgroups according to changes in body weight. Results : Fifty-eight participants (25.6% were assigned to group 1 (≥ 1.5% decrease in body weight after 16 weeks, 32 participants (14.1% were assigned to group 2 (1.5-0.1% decrease in body weight, and 136 participants (59.9% were assigned to group 3 (≥ 0.0% increase in body weight. Characteristics at enrollment were not different among the three groups, but mean differences in weight and percent changes in urinary sodium excretion over the period were statistically different (P < 0.001 and P = 0.017. Over the study period, unintentional weight loss independently increased the probability of reduced albuminuria (group 1, relative risk 6.234, 95% confidence interval 1.913-20.315, P = 0.002. Among urinary cytokines, only podocalyxin level decreased significantly in participants who lost weight (P = 0.013. Conclusion : We observed that weight loss had an additive effect on the anti-proteinuric effects of ARBs in nondiabetic hypertensive CKD patients, although it was minimal. An additive effect was shown in both obese and non-obese participants, and its possible mechanism is related to reduction of podocyte damage.

  18. Perspective

    DEFF Research Database (Denmark)

    Kussmann, Martin; Morine, Melissa J; Hager, Jörg

    2013-01-01

    We review here the status of human type 2 diabetes studies from a genetic, epidemiological, and clinical (intervention) perspective. Most studies limit analyses to one or a few omic technologies providing data of components of physiological processes. Since all chronic diseases are multifactorial...... at different time points along this longitudinal investigation are performed with a comprehensive set of omics platforms. These data sets are generated in a biological context, rather than biochemical compound class-driven manner, which we term "systems omics."...

  19. Reduction of heat losses on the skid pipe system of reheating furnaces in the steel industry; Verringerung der Waermeverluste am Tragrohrsystem von Waermeoefen in der Stahlindustrie

    Energy Technology Data Exchange (ETDEWEB)

    Springer, Michael; Huegel, Frank [FBB Engineering GmbH, Moenchengladbach (Germany)

    2011-06-15

    New technology can improve the energy efficiency of thermo processing equipment, innovative technology can ultimately help to reduce CO{sub 2} emissions from existing facilities and simultaneously ensure that the equipment can also operate more economically. The result of consequent development at FBB ENGINEERING GmbH for insulation of skid pipe systems of reheating furnaces in steel industry (walking beam -, pusher type furnace) are efficient pre-fabricated shells made of ultra-light weight castable FLB-11/150-I1 with thermo technical optimized sandwich design that lead to significant and sustainable reduction of heat losses and are responsible for high energy saving potential. Thermo technical CFD simulations, laboratory tests, field trials and complete installations of skid pipe systems show that compared to dense castable heat loss in the skid pipe cooling systems can be reduced up to 30 % and more with pre-fabricated shells made of ultra-light weight castable FLB-11/150-I1. (orig.)

  20. The prevention and reduction of weight loss in an acute tertiary care setting: protocol for a pragmatic stepped wedge randomised cluster trial (the PRoWL project)

    Science.gov (United States)

    2013-01-01

    Background Malnutrition, with accompanying weight loss, is an unnecessary risk in hospitalised persons and often remains poorly recognised and managed. The study aims to evaluate a hospital-wide multifaceted intervention co-facilitated by clinical nurses and dietitians addressing the nutritional care of patients, particularly those at risk of malnutrition. Using the best available evidence on reducing and preventing unplanned weight loss, the intervention (introducing universal nutritional screening; the provision of oral nutritional supplements; and providing red trays and additional support for patients in need of feeding) will be introduced by local ward teams in a phased way in a large tertiary acute care hospital. Methods/Design A pragmatic stepped wedge randomised cluster trial with repeated cross section design will be conducted. The unit of randomisation is the ward, with allocation by a random numbers table. Four groups of wards (n = 6 for three groups, n = 7 for one group) will be randomly allocated to each intervention time point over the trial. Two trained local facilitators (a nurse and dietitian for each group) will introduce the intervention. The primary outcome measure is change in patient’s body weight, secondary patient outcomes are: length of stay, all-cause mortality, discharge destinations, readmission rates and ED presentations. Patient outcomes will be measured on one ward per group, with 20 patients measured per ward per time period by an unblinded researcher. Including baseline, measurements will be conducted at five time periods. Staff perspectives on the context of care will be measured with the Alberta Context Tool. Discussion Unplanned and unwanted weight loss in hospital is common. Despite the evidence and growing concern about hospital nutrition there are very few evaluations of system-wide nutritional implementation programs. This project will test the implementation of a nutritional intervention across one hospital system using a

  1. Post-harvest loss reduction

    NARCIS (Netherlands)

    Gogh, van Bart; Boerrigter, Henry; Noordam, Maryvon; Ruben, Ruerd; Timmermans, Toine

    2017-01-01

    This paper was written by experts from Wageningen University & Research (WUR), representing their combined expertise on food chains, post-harvest technology, sustainability, food security, economics, and food safety. The paper was drafted at the request of the Dutch Ministry of Economic Affairs

  2. Student Teachers' Understanding of the Terminology, Distribution, and Loss of Biodiversity: Perspectives from a Biodiversity Hotspot and an Industrialized Country

    Science.gov (United States)

    Fiebelkorn, Florian; Menzel, Susanne

    2013-01-01

    The loss of biodiversity is one of the most urgent global environmental problems of our time. Public education and awareness building is key to successful biodiversity protection. Knowledgeable and skilled student teachers are a key component for the successful implementation of biodiversity education in schools. Yet, little empirical evidence…

  3. Bone-anchored hearing devices in children with unilateral conductive hearing loss: a patient-carer perspective.

    Science.gov (United States)

    Banga, Rupan; Doshi, Jayesh; Child, Anne; Pendleton, Elizabeth; Reid, Andrew; McDermott, Ann-Louise

    2013-09-01

    We sought to determine the outcome of implantation of a bone-anchored hearing device in children with unilateral conductive hearing loss. A retrospective case note analysis was used in a tertiary referral pediatric hospital to study 17 consecutive cases of pediatric patients with unilateral conductive hearing loss who were fitted with a bone-anchored hearing device between 2005 and 2010. The average age of the patients at the time of bone-anchored hearing device fitting was 10 years 6 months (range, 6 years 3 months to 16 years). Qualitative subjective outcome measures demonstrated benefit. The vast majority of patients reported improved social and physical functioning and improved quality of life. All 17 patients are currently using their bone-anchored hearing device on a daily basis after a follow-up of 6 months. This study has shown improved quality of life in children with unilateral hearing loss after implantation of their bone-anchored hearing device. There was a high degree of patient satisfaction and improvement in health status reported by children and/or carers. Bone-anchored hearing devices have an important role in the management of children with symptomatic unilateral hearing loss. Perhaps earlier consideration of a bone-anchored hearing device would be appropriate in selected cases.

  4. Electron-beam-induced reduction of Fe3+ in iron phosphate dihydrate, ferrihydrite, haemosiderin and ferritin as revealed by electron energy-loss spectroscopy

    International Nuclear Information System (INIS)

    Pan, Ying-Hsi; Vaughan, Gareth; Brydson, Rik; Bleloch, Andrew; Gass, Mhairi; Sader, Kasim; Brown, Andy

    2010-01-01

    The effect of high-energy electron irradiation on ferritin/haemosiderin cores (in an iron-overloaded human liver biopsy), its mineral analogue; six-line ferrihydrite (6LFh), and iron phosphate dihydrate (which has similar octahedral ferric iron to oxygen coordination to that in ferrihydrite and ferritin/haemosiderin cores) has been investigated using electron energy-loss spectroscopy (EELS). Fe L 2,3 -ionisation edges were recorded on two types of electron microscope: a 200 keV transmission electron microscope (TEM) and a 100 keV scanning transmission electron microscope (STEM), in order to investigate the damage mechanisms in operation and to establish a methodology for minimum specimen alteration during analytical electron microscopic characterisation. A specimen damage mechanism dominated by radiolysis that results in the preferential loss of iron co-ordinating ligands (O, OH and H 2 O) is discussed. The net result of irradiation is structural re-organisation and reduction of iron within the iron hydroxides. At sufficiently low electron fluence and particularly in the lower incident energy, finer probe diameter STEM, the alteration is shown to be minimal. All the materials examined exhibit damage which as a function of cumulative fluence is best fitted by an inverse power-law, implying that several chemical and structural changes occur in response to the electron beam and we suggest that these are governed by secondary processes arising from the primary ionisation event. This work affirms that electron fluence and current density should be considered when measuring mixed valence ratios with EELS.

  5. Electron-beam-induced reduction of Fe{sup 3+} in iron phosphate dihydrate, ferrihydrite, haemosiderin and ferritin as revealed by electron energy-loss spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Ying-Hsi; Vaughan, Gareth; Brydson, Rik [Institute for Materials Research, SPEME, University of Leeds, Leeds LS2 9JT (United Kingdom); Bleloch, Andrew; Gass, Mhairi [SuperSTEM, Daresbury Laboratories, Warrington WA4 4AD (United Kingdom); Sader, Kasim [Institute for Materials Research, SPEME, University of Leeds, Leeds LS2 9JT (United Kingdom); SuperSTEM, Daresbury Laboratories, Warrington WA4 4AD (United Kingdom); Brown, Andy, E-mail: a.p.brown@leeds.ac.uk [Institute for Materials Research, SPEME, University of Leeds, Leeds LS2 9JT (United Kingdom)

    2010-07-15

    The effect of high-energy electron irradiation on ferritin/haemosiderin cores (in an iron-overloaded human liver biopsy), its mineral analogue; six-line ferrihydrite (6LFh), and iron phosphate dihydrate (which has similar octahedral ferric iron to oxygen coordination to that in ferrihydrite and ferritin/haemosiderin cores) has been investigated using electron energy-loss spectroscopy (EELS). Fe L{sub 2,3}-ionisation edges were recorded on two types of electron microscope: a 200 keV transmission electron microscope (TEM) and a 100 keV scanning transmission electron microscope (STEM), in order to investigate the damage mechanisms in operation and to establish a methodology for minimum specimen alteration during analytical electron microscopic characterisation. A specimen damage mechanism dominated by radiolysis that results in the preferential loss of iron co-ordinating ligands (O, OH and H{sub 2}O) is discussed. The net result of irradiation is structural re-organisation and reduction of iron within the iron hydroxides. At sufficiently low electron fluence and particularly in the lower incident energy, finer probe diameter STEM, the alteration is shown to be minimal. All the materials examined exhibit damage which as a function of cumulative fluence is best fitted by an inverse power-law, implying that several chemical and structural changes occur in response to the electron beam and we suggest that these are governed by secondary processes arising from the primary ionisation event. This work affirms that electron fluence and current density should be considered when measuring mixed valence ratios with EELS.

  6. Magnetic resonance imaging signal reduction may precede volume loss in the pituitary gland of transfusion-dependent beta-thalassemic patients

    Energy Technology Data Exchange (ETDEWEB)

    Hekmatnia, Ali; Rahmani, Ali Asghar; Adibi, Atoosa (Image Processing and Signal Research Center, Dept. of Radiology, Isfahan Univ. of Medical Sciences, Isfahan (Iran)); Radmard, Amir Reza (Dept. of Radiology, Shariati Hospital, Tehran Univ. of Medical Sciences, Tehran (Iran)); Khademi, Hooman (Shariati Hospital, Tehran Univ. of Medical Sciences, Tehran (Iran)), e-mail: radmard@ams.ac.ir

    2010-01-15

    Background: Pituitary iron overload in patients with transfusion-dependent beta-thalassemia may lead to delayed puberty. Magnetic resonance imaging (MRI) has the potential to estimate tissue iron concentration by detecting its paramagnetic effect and hypophyseal damage by measuring its dimensions indirectly. Purpose: To investigate the association of pituitary MRI findings and pubertal status in thalassemic patients as well as to demonstrate any priority in appearance of them. Material and Methods: Twenty-seven beta-thalassemic patients, aged 15-25 years, were divided into 13 with (group A) and 14 without hypogonadism (group B), matched by age, gender, duration of transfusion, and chelation therapy. Thirty-eight age- and sex-adjusted healthy control individuals were also included (group C). All participants underwent pituitary MRI using a 1.5T unit. Pituitary-to-fat signal intensity ratios (SIR) were calculated from coronal T2-weighted images. Estimated pituitary volumes were measured using pituitary height, width, and length on T1-weighted images. Results: The mean values of pituitary-to-fat SIRs were significantly lower in group A as compared with group B (P <0.001), and likewise group B had statistically lower values than group C (P=0.03). The pituitary height and volume were significantly decreased in group A compared to group B (P = 0.006 and P = 0.002, respectively), while these differences did not demonstrate statistically significance between groups B and C. Conclusion: Pituitary MRI findings such as signal intensity reduction and decrease in volume can be useful markers in estimating pituitary dysfunction in beta-thalassemic patients. Compared to healthy controls, lower values of pituitary-to-fat SIRs in thalassemic patients experiencing normal puberty, without marked decrease in volume, indicate that signal reduction may precede volume loss and could be expected first on MRI

  7. Effect of emergency core cooling system flow reduction on channel temperature during recirculation phase of large break loss-of-coolant accident at Wolsong unit 1

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Seon Oh; Cho, Yong Jin [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of); Kim, Sung Joong [Dept. of Nuclear Engineering, Hanyang University, Seoul (Korea, Republic of)

    2017-08-15

    The feasibility of cooling in a pressurized heavy water reactor after a large break loss-of-coolant accident has been analyzed using Multidimensional Analysis of Reactor Safety-KINS Standard code during the recirculation phase. Through evaluation of sensitivity of the fuel channel temperature to various effective recirculation flow areas, it is determined that proper cooling of the fuel channels in the broken loop is feasible if the effective flow area remains above approximately 70% of the nominal flow area. When the flow area is reduced by more than approximately 25% of the nominal value, however, incipience of boiling is expected, after which the thermal integrity of the fuel channel can be threatened. In addition, if a dramatic reduction of the recirculation flow occurs, excursions and frequent fluctuations of temperature in the fuel channels are likely to be unavoidable, and thus damage to the fuel channels would be anticipated. To resolve this, emergency coolant supply through the newly installed external injection path can be used as one alternative means of cooling, enabling fuel channel integrity to be maintained and permanently preventing severe accident conditions. Thus, the external injection flow required to guarantee fuel channel coolability has been estimated.

  8. Effect of emergency core cooling system flow reduction on channel temperature during recirculation phase of large break loss-of-coolant accident at Wolsong unit 1

    Directory of Open Access Journals (Sweden)

    Seon Oh Yu

    2017-08-01

    Full Text Available The feasibility of cooling in a pressurized heavy water reactor after a large break loss-of-coolant accident has been analyzed using Multidimensional Analysis of Reactor Safety-KINS Standard code during the recirculation phase. Through evaluation of sensitivity of the fuel channel temperature to various effective recirculation flow areas, it is determined that proper cooling of the fuel channels in the broken loop is feasible if the effective flow area remains above approximately 70% of the nominal flow area. When the flow area is reduced by more than approximately 25% of the nominal value, however, incipience of boiling is expected, after which the thermal integrity of the fuel channel can be threatened. In addition, if a dramatic reduction of the recirculation flow occurs, excursions and frequent fluctuations of temperature in the fuel channels are likely to be unavoidable, and thus damage to the fuel channels would be anticipated. To resolve this, emergency coolant supply through the newly installed external injection path can be used as one alternative means of cooling, enabling fuel channel integrity to be maintained and permanently preventing severe accident conditions. Thus, the external injection flow required to guarantee fuel channel coolability has been estimated.

  9. Can mountain glacier melting explains the GRACE-observed mass loss in the southeast Tibetan Plateau: From a climate perspective?

    Science.gov (United States)

    Song, Chunqiao; Ke, Linghong; Huang, Bo; Richards, Keith S.

    2015-01-01

    The southeast Tibetan Plateau (SETP) includes the majority of monsoonal temperate glaciers in High Mountain Asia (HMA), which is an important source of water for the upper reaches of several large Asian river systems. Climatic change and variability has substantial impacts on cryosphere and hydrological processes in the SETP. The Gravity Recovery and Climate Experiment (GRACE) gravimetry observations between 2003 and 2009 suggest that there was an average mass loss rate of - 5.99 ± 2.78 Gigatonnes (Gt)/yr in this region. Meanwhile, the hydrological data by model calculations from the GLDAS/Noah and CPC are used to estimate terrestrial water storage (TWS) changes with a slight negative trend of about - 0.3 Gt/yr. The recent studies (Kääb et al., 2012; Gardner et al., 2013) reported the thinning rates of mountain glaciers in HMA based on the satellite laser altimetry, and an approximate estimation of the glacier mass budget in the SETP was 4.69 ± 2.03 Gt/yr during 2003-2009. This estimate accounted for a large proportion ( 78.3%) of the difference between the GRACE TWS and model-calculated TWS changes. To better understand the cause of sharp mass loss existing in the SETP, the correlations between key climatic variables (precipitation and temperature) and the GRACE TWS changes are examined at different timescales between 2003 and 2011. The results show that precipitation is the leading factors of abrupt, seasonal and multi-year undulating signals of GRACE TWS anomaly time series, but with weak correlations with the inter-annual trend and annual mass budget of GRACE TWS. In contrast, the annual mean temperature is tightly associated with the annual net mass budget (r = 0.81, p < 0.01), which indirectly suggests that the GRACE-observed mass loss in the SETP may be highly related to glacial processes.

  10. A comprehensive analysis of China's regional energy saving and emission reduction efficiency: From production and treatment perspectives

    International Nuclear Information System (INIS)

    Wu, Jie; Lv, Lin; Sun, Jiasen; Ji, Xiang

    2015-01-01

    Energy and environmental issues have recently aroused increasing interest in China and many approaches are used to evaluate energy and environmental performance. In this paper, a two-stage network DEA framework is applied to evaluate the efficiency of energy saving and emission reduction in China during the period of the eleventh five-year plan, from 2006 to 2010. In this study, economic activities are divided into production and treatment processes. This is different from previous research which generally focused on either environmental efficiency or energy efficiency, omitting the integration of energy and environmental measures. Today, energy saving and emission reduction are both parts of the basic state policy of China and are equally important. The empirical results in this study show that: (i) eastern China has the best energy saving and emission reduction efficiency, performing is better than western and central China. (ii) The efficiency of the production process in central China is better than that in western China while the western area performs better than the central area in term of treatment efficiency. (iii) Integrated efficiency of energy saving and emission reduction of China was relatively stable in the five years and the pollution treatment efficiency maintained a rising trend. -- Highlights: •We measured China's regional energy saving and emission reduction efficiency using two-stage DEA approach. •The production and treatment processes are incorporated in evaluation. •Eastern China performs best in terms of energy saving and emission reduction efficiency. •Integrated efficiency of energy saving and emission reduction of China kept a stable trend during 2006–2010

  11. Patients' perspectives on electroconvulsive therapy: a reevaluation of the review by Rose et al on memory loss after electroconvulsive therapy.

    Science.gov (United States)

    Bergsholm, Per

    2012-03-01

    In 2003, based on a review of 7 studies, Rose et al concluded that at least one third of patients report significant memory loss 6 months or more after electroconvulsive therapy (ECT). However, few details on the included studies were given. The present study evaluates factors that may have influenced the results. The 7 studies were scrutinized as to the 6-month assessment criterion, whether the data represent ECT-treated patients in general, specification and significance of the memory loss, stimulus type, and electrode placement. In 3 studies, the 6-month inclusion criterion was not met, including 1 study with 98% satisfied patients and 1 study with only 37% valid response rate. Two other studies selected individuals from user/advocacy groups generally biased against ECT and were probably overlapping. The significance of memory problems was not mentioned in any of the studies. Two studies reported that 30% and 55% of patients treated with bilateral ECT in the 1970s felt they had persistent memory gaps around the time of treatment, but the long-obsolete sine wave stimulus type was used. The results mostly concerned bilateral ECT, whereas unilateral ECT seemed to cause little complaints. Data used by Rose et al are severely flawed, making their results inconclusive and misleading.

  12. Learning from losing: ethical, psychoanalytic, and spiritual perspectives on managing the incremental losses of the distributed self in dementia.

    Science.gov (United States)

    Lomax, James W

    2011-01-01

    The author describes his experiences making decisions about the care of his mother, who was suffering from dementia, and the profound effect this process had on him as a psychotherapist. As background, he first presents an overview of writings from Jerry M. Lewis, George Pollock, and George Vaillant on issues related to attachment, death, loss, and mourning. The author equates his experiences caring for his mother with a type of involuntary "continuing education" and describes the lessons he learned as he was faced with decisions about his mother's level of care and as he mourned the slow, piecemeal loss of her distributed self. A case vignette is presented to illustrate how the author applied the lessons he had learned in psychotherapy with a distressed patient caring for her aging mother. The article concludes with a summary of the clinical and ethical questions raised by this case and the author's experience with his mother and a discussion of principles that can help psychotherapists provide treatment for patients who are caring for family members with dementia. (Journal of Psychiatric Practice. 2011;17:41-48).

  13. Towards improved public awareness for climate related disaster risk reduction in South Africa: A Participatory Development Communication perspective

    Directory of Open Access Journals (Sweden)

    Tigere Chagutah

    2009-04-01

    Full Text Available Southern Africa has frequently been struck by damaging climate hazards which increasingly continue to threaten sustainable development efforts. Ominously, climate models predict that the incidence of major ‘wet’ events, such as floods and cyclones will increase in frequency against the background of a changing climate. Unfortunately, local mechanisms for communicating and raising public awareness of the consequent risks and appropriate risk reduction options remain weak. At the core of policy responses to the threat posed by climate related hazards, the South African government has adopted a disaster risk reduction approach to disaster management. This article details how, among many other measures to limit the adverse impacts of natural hazards, South Africa’s National Disaster Management Framework calls for the implementation of effective public awareness activities to increase the knowledge among communities of the risks they face and what risk-minimising actions they can take. Emphasis is laid on the importance of information provision and knowledge building among at-risk communities. Citing established theories and strategies, the author proposes a participatory development communication approach through Development Support Communication strategies for the provision of disaster risk reduction public awareness activities by government and other disaster risk reduction role-players in South Africa. By way of a review of completed studies and literature, the article provides guidance on the planning and execution of successful public communication campaigns and also discusses the constraints of communication campaigns as an intervention for comprehensive disaster risk reduction.

  14. Instruments. Climate protection of reduction of no-load losses in electric appliances and equipment; Klimaschutz durch Minderung von Leerlaufverlusten bei Elektrogeraeten. Instrumente

    Energy Technology Data Exchange (ETDEWEB)

    Rath, U.; Hellmann, R. [Ingenieurbuero fuer Energieberatung, Haustechnik und Oekologische Konzepte GbR (eboek), Tuebingen (Germany); Moehring-Hueser, W.; Wortmann, K.; Bregas, J. [Energiestiftung Schleswig-Holstein, Kiel (Germany); Mordziol, C. [Umweltbundesamt, Berlin (Germany)

    1999-12-01

    Two studies on the subject of 'Climate Protection through Reduction of No-load Losses in Electric Applicances and Equipment' have been performed on behalf of the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety and the German Federal Environmental Agency. The first study, carried out by the Tuebingen-based engineering bureau eboek, has been published in the Federal Environmental Agency's TEXTE series (Texte 45/97, 2{sup nd} edition, 1998). It was the starting point for a multitude of activities among them two information campaigns carried out in 1998 and 1999 that were funded by the Federal Ministry for the Environment and the German Section of the Friends of the Earth (BUND). The study also served as a basis for decisions taken by the German Bundestag and the Bundesrat (Council of Constituent States). The second study on the subject was carried out by the engineering bureau eboek and Energiestiftung Schleswig-Holstein. Building on the results obtained in the first study, it presents estimates of relevant data for the European Union and examines various approaches for possible measures to reduce no-load losses as to their suitability. The studies impressively show that effective climate protection can be achieved in all relevant sectors, and in many cases even save costs. The results are detailed below. (orig.) [German] Im Auftrag des Bundesministeriums fuer Umwelt, Naturschutz und Reaktorsicherheit sowie des Umweltbundesamtes wurden zwei Studien zum Thema: 'Klimaschutz durch Minderung von Leerlaufverlusten bei Elektrogeraeten' durchgefuehrt: Die erste, vom Ingenieurbuero fuer Energieberatung, Haustechnik und oekologische Konzepte (eboek), Tuebingen, earbeitete Studie wurde in der Reihe TEXTE des UBA veroeffentlicht (Texte 45/97, 2. Auflage 1998). Sie bildete den Ausgangspunkt fuer eine Vielzahl von Aktivitaeten, unter anderem zwei vom Bundesumweltministerium finanzierte und vom Bund fuer Umwelt und

  15. Instruments. Climate protection of reduction of no-load losses in electric appliances and equipment; Klimaschutz durch Minderung von Leerlaufverlusten bei Elektrogeraeten. Instrumente

    Energy Technology Data Exchange (ETDEWEB)

    Rath, U; Hellmann, R [Ingenieurbuero fuer Energieberatung, Haustechnik und Oekologische Konzepte GbR (eboek), Tuebingen (Germany); Moehring-Hueser, W; Wortmann, K; Bregas, J [Energiestiftung Schleswig-Holstein, Kiel (Germany); Mordziol, C [Umweltbundesamt, Berlin (Germany)

    1999-12-01

    Two studies on the subject of 'Climate Protection through Reduction of No-load Losses in Electric Applicances and Equipment' have been performed on behalf of the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety and the German Federal Environmental Agency. The first study, carried out by the Tuebingen-based engineering bureau eboek, has been published in the Federal Environmental Agency's TEXTE series (Texte 45/97, 2{sup nd} edition, 1998). It was the starting point for a multitude of activities among them two information campaigns carried out in 1998 and 1999 that were funded by the Federal Ministry for the Environment and the German Section of the Friends of the Earth (BUND). The study also served as a basis for decisions taken by the German Bundestag and the Bundesrat (Council of Constituent States). The second study on the subject was carried out by the engineering bureau eboek and Energiestiftung Schleswig-Holstein. Building on the results obtained in the first study, it presents estimates of relevant data for the European Union and examines various approaches for possible measures to reduce no-load losses as to their suitability. The studies impressively show that effective climate protection can be achieved in all relevant sectors, and in many cases even save costs. The results are detailed below. (orig.) [German] Im Auftrag des Bundesministeriums fuer Umwelt, Naturschutz und Reaktorsicherheit sowie des Umweltbundesamtes wurden zwei Studien zum Thema: 'Klimaschutz durch Minderung von Leerlaufverlusten bei Elektrogeraeten' durchgefuehrt: Die erste, vom Ingenieurbuero fuer Energieberatung, Haustechnik und oekologische Konzepte (eboek), Tuebingen, earbeitete Studie wurde in der Reihe TEXTE des UBA veroeffentlicht (Texte 45/97, 2. Auflage 1998). Sie bildete den Ausgangspunkt fuer eine Vielzahl von Aktivitaeten, unter anderem zwei vom Bundesumweltministerium finanzierte und vom Bund fuer Umwelt und Naturschutz (BUND) 1998 und

  16. Assessing the economic impacts of drought from the perspective of profit loss rate: a case study of the sugar industry in China

    Science.gov (United States)

    Wang, Y.; Lin, L.; Chen, H.

    2015-07-01

    Natural disasters have enormous impacts on human society, especially on the development of the economy. To support decision-making in mitigation and adaption to natural disasters, assessment of economic impacts is fundamental and of great significance. Based on a review of the literature on economic impact evaluation, this paper proposes a new assessment model of the economic impacts of droughts by using the sugar industry in China as a case study, which focuses on the generation and transfer of economic impacts along a simple value chain involving only sugarcane growers and a sugar-producing company. A perspective of profit loss rate is applied to scale economic impact. By using "with and without" analysis, profit loss is defined as the difference in profits between disaster-hit and disaster-free scenarios. To calculate profit, analysis of a time series of sugar price is applied. With the support of a linear regression model, an endogenous trend in sugar price is identified and the time series of sugar price "without" disaster is obtained, using an autoregressive error model to separate impact of disasters from the internal trend in sugar price. Unlike the settings in other assessment models, representative sugar prices, which represent value level in disaster-free conditions and disaster-hit conditions, are integrated from a long time series that covers the whole period of drought. As a result, it is found that in a rigid farming contract, sugarcane growers suffer far more than the sugar company when impacted by severe drought, which may promote reflections among various economic bodies on economic equality related to the occurrence of natural disasters. Further, sensitivity analysis of the model built reveals that sugarcane purchase price has a significant influence on profit loss rate, which implies that setting a proper sugarcane purchase price would be an effective way of realizing economic equality in future practice of contract farming.

  17. Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase.

    Directory of Open Access Journals (Sweden)

    Zeynep A Oztug Durer

    Full Text Available Mutations in the gene encoding Cu-Zn superoxide dismutase (SOD1 are one of the causes of familial amyotrophic lateral sclerosis (FALS. Fibrillar inclusions containing SOD1 and SOD1 inclusions that bind the amyloid-specific dye thioflavin S have been found in neurons of transgenic mice expressing mutant SOD1. Therefore, the formation of amyloid fibrils from human SOD1 was investigated. When agitated at acidic pH in the presence of low concentrations of guanidine or acetonitrile, metalated SOD1 formed fibrillar material which bound both thioflavin T and Congo red and had circular dichroism and infrared spectra characteristic of amyloid. While metalated SOD1 did not form amyloid-like aggregates at neutral pH, either removing metals from SOD1 with its intramolecular disulfide bond intact or reducing the intramolecular disulfide bond of metalated SOD1 was sufficient to promote formation of these aggregates. SOD1 formed amyloid-like aggregates both with and without intermolecular disulfide bonds, depending on the incubation conditions, and a mutant SOD1 lacking free sulfhydryl groups (AS-SOD1 formed amyloid-like aggregates at neutral pH under reducing conditions. ALS mutations enhanced the ability of disulfide-reduced SOD1 to form amyloid-like aggregates, and apo-AS-SOD1 formed amyloid-like aggregates at pH 7 only when an ALS mutation was also present. These results indicate that some mutations related to ALS promote formation of amyloid-like aggregates by facilitating the loss of metals and/or by making the intramolecular disulfide bond more susceptible to reduction, thus allowing the conversion of SOD1 to a form that aggregates to form resembling amyloid. Furthermore, the occurrence of amyloid-like aggregates per se does not depend on forming intermolecular disulfide bonds, and multiple forms of such aggregates can be produced from SOD1.

  18. Relating hearing loss and executive functions to hearing aid users’ preference for, and speech recognition with, different combinations of binaural noise reduction and microphone directionality

    Directory of Open Access Journals (Sweden)

    Tobias eNeher

    2014-12-01

    Full Text Available Knowledge of how executive functions relate to preferred hearing aid (HA processing is sparse and seemingly inconsistent with related knowledge for speech recognition outcomes. This study thus aimed to find out if (1 performance on a measure of reading span (RS is related to preferred binaural noise reduction (NR strength, (2 similar relations exist for two different, nonverbal measures of executive function, (3 pure-tone average hearing loss (PTA, signal-to-noise ratio (SNR, and microphone directionality (DIR also influence preferred NR strength, and (4 preference and speech recognition outcomes are similar. Sixty elderly HA users took part. Six HA conditions consisting of omnidirectional or cardioid microphones followed by inactive, moderate, or strong binaural NR as well as linear amplification were tested. Outcome was assessed at fixed SNRs using headphone simulations of a frontal target talker in a busy cafeteria. Analyses showed positive effects of active NR and DIR on preference, and negative and positive effects of, respectively, strong NR and DIR on speech recognition. Also, while moderate NR was the most preferred NR setting overall, preference for strong NR increased with SNR. No relation between RS and preference was found. However, larger PTA was related to weaker preference for inactive NR and stronger preference for strong NR for both microphone modes. Equivalent (but weaker relations between worse performance on one nonverbal measure of executive function and the HA conditions without DIR were found. For speech recognition, there were relations between HA condition, PTA, and RS, but their pattern differed from that for preference. Altogether, these results indicate that, while moderate NR works well in general, a notable proportion of HA users prefer stronger NR. Furthermore, PTA and executive functions can account for some of the variability in preference for, and speech recognition with, different binaural NR and DIR settings.

  19. Predictors of weight loss and maintenance during 2 years of treatment by sibutramine in obesity. Results from the European multi-centre STORM trial. Sibutramine Trial of Obesity Reduction and Maintenance

    DEFF Research Database (Denmark)

    Hansen, D; Astrup, A; Toubro, S

    2001-01-01

    In this report we assess pre-treatment determinants of weight loss and maintenance outcome in The Sibutramine Trial of Obesity Reduction and Maintenance (STORM), a 2 y randomized, double-blind, placebo-controlled, European multicenter study examining the effect of sibutramine (Sib) on inducing...

  20. The public perspective of carbon capture and storage for CO{sub 2} emission reductions in China

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Hongxia [China Center for Energy Economics Research, Building B202, School of Economics, Xiamen University Siming Nanlu No. 422 361005 Xiamen, Fujian (China)

    2010-09-15

    To explore public awareness of carbon capture and storage (CCS), attitudes towards the use of CCS and the determinants of CCS acceptance in China, a study was conducted in July 2009 based on face-to-face interviews with participants across the country. The result showed that the awareness of CCS was low among the surveyed public in China, compared to other clean energy technologies. Respondents indicated a slightly supportive attitude towards the use of CCS as an alternative technology to CO{sub 2} emission reductions. The regression model revealed that in addition to CCS knowledge, respondents' understanding of the characteristics of CCS, such as the maturity of the technology, risks, capability of CO2 emission reductions, and CCS policy were all significant factors in predicting the acceptance of CCS. The findings suggest that integrating public education and communication into CCS development policy would be an effective strategy to overcome the barrier of low public acceptance. (author)

  1. The public perspective of carbon capture and storage for CO{sub 2} emission reductions in China

    Energy Technology Data Exchange (ETDEWEB)

    Duan Hongxia, E-mail: hxduan@xmu.edu.c [China Center for Energy Economics Research, Building B202, School of Economics, Xiamen University Siming Nanlu No. 422 361005 Xiamen, Fujian (China)

    2010-09-15

    To explore public awareness of carbon capture and storage (CCS), attitudes towards the use of CCS and the determinants of CCS acceptance in China, a study was conducted in July 2009 based on face-to-face interviews with participants across the country. The result showed that the awareness of CCS was low among the surveyed public in China, compared to other clean energy technologies. Respondents indicated a slightly supportive attitude towards the use of CCS as an alternative technology to CO{sub 2} emission reductions. The regression model revealed that in addition to CCS knowledge, respondents' understanding of the characteristics of CCS, such as the maturity of the technology, risks, capability of CO2 emission reductions, and CCS policy were all significant factors in predicting the acceptance of CCS. The findings suggest that integrating public education and communication into CCS development policy would be an effective strategy to overcome the barrier of low public acceptance.

  2. Tsunami survivors' perspectives on vulnerability and vulnerability reduction: evidence from Koh Phi Phi Don and Khao Lak, Thailand.

    Science.gov (United States)

    Steckley, Marylynn; Doberstein, Brent

    2011-07-01

    This paper presents the results of primary research with 40 survivors of the 2004 Indian Ocean tsunami in two communities: Khao Lak (n=20) and Koh Phi Phi Don (n=20), Thailand. It traces tsunami survivors' perceptions of vulnerability, determines whether residents felt that the tsunami affected different communities differently, identifies the populations and sub-community groups that survivors distinguished as being more vulnerable than others, highlights community-generated ideas about vulnerability reduction, and pinpoints a range of additional vulnerability reduction actions. Tsunami survivors most consistently identified the 'most vulnerable' community sub-populations as women, children, the elderly, foreigners, and the poor. In Khao Lak, however, respondents added 'Burmese migrants' to this list, whereas in Koh Phi Phi Don, they added 'Thai Muslims'. Results suggest that the two case study communities, both small, coastal, tourism-dominated communities no more than 100 kilometres apart, have differing vulnerable sub-groups and environmental vulnerabilities, requiring different post-disaster vulnerability reduction efforts. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.

  3. Origin of the Reductive Tricarboxylic Acid (rTCA Cycle-Type CO2 Fixation: A Perspective

    Directory of Open Access Journals (Sweden)

    Norio Kitadai

    2017-10-01

    Full Text Available The reductive tricarboxylic acid (rTCA cycle is among the most plausible candidates for the first autotrophic metabolism in the earliest life. Extant enzymes fixing CO2 in this cycle contain cofactors at the catalytic centers, but it is unlikely that the protein/cofactor system emerged at once in a prebiotic process. Here, we discuss the feasibility of non-enzymatic cofactor-assisted drive of the rTCA reactions in the primitive Earth environments, particularly focusing on the acetyl-CoA conversion to pyruvate. Based on the energetic and mechanistic aspects of this reaction, we propose that the deep-sea hydrothermal vent environments with active electricity generation in the presence of various sulfide catalysts are a promising setting for it to progress. Our view supports the theory of an autotrophic origin of life from primordial carbon assimilation within a sulfide-rich hydrothermal vent.

  4. Flash flooding: Toward an Interdisciplinary and Integrated Strategy for Disaster Reduction in a Global Environmental Change Perspective

    Science.gov (United States)

    Ruin, Isabelle

    2014-05-01

    How do people answer to heavy precipitation and flood warnings? How do they adapt their daily schedule and activity to the fast evolution of the environmental circumstances? More generally, how do social processes interact with physical ones? Such questions address the dynamical interactions between hydro-meteorological variables, human perception and representation of the environment, and actual individual and social behavioral responses. It also poses the question of scales and hierarchy issues through seamless interactions between smaller and larger scales. These questions are relevant for both social and physical scientists. They are more and more pertinently addressed in the Global Environmental Change perspective through the concepts of Coupled Human And Natural Systems (CHANS), resilience or panarchy developped in the context of interdisciplinary collaborations. Nevertheless those concepts are complex and not easy to handle, specially when facing with operational goals. One of the main difficulty to advance these integrated approaches is the access to empirical data informing the processes at various scales. In fact, if physical and social processes are well studied by distinct disciplines, they are rarely jointly explored within similar spatial and temporal resolutions. Such coupled observation and analysis poses methodological challenges, specially when dealing with responses to short-fuse and extreme weather events. In fact, if such coupled approach is quite common to study large scale phenomenon like global change (for instance using historical data on green house gaz emissions and the evolution of temperatures worldwide), it is rarer for studing smaller nested sets of scales of human-nature systems where finer resolution data are sparse. Another problem arise from the need to produce comparable analysis on different case studies where social, physical and even cultural contexts may be diverse. Generic and robust framework for data collection, modeling

  5. Leisure-time activity is an important determinant of long-term weight maintenance after weight loss in the Sibutramine Trial on Obesity Reduction and Maintenance (STORM trial)

    DEFF Research Database (Denmark)

    van Baak, M. A.; van Mil, E.; Astrup, A.

    2003-01-01

    The success rate of long-term maintenance of weight loss in obese patients is usually low. To improve the success rate, determinants of long-term weight maintenance must be identified.......The success rate of long-term maintenance of weight loss in obese patients is usually low. To improve the success rate, determinants of long-term weight maintenance must be identified....

  6. Sustainability of 8% weight loss, reduction of insulin resistance, and amelioration of atherogenic-metabolic risk factors over 4 years by metformin-diet in women with polycystic ovary syndrome.

    Science.gov (United States)

    Glueck, Charles J; Aregawi, Dawit; Agloria, Mahlia; Winiarska, Magdalena; Sieve, Luann; Wang, Ping

    2006-12-01

    In 74 women with polycystic ovary syndrome, treated for 4 years with metformin (MET) and diet, we prospectively assessed whether, and to what degree, weight loss, reduction of insulin resistance, and amelioration of coronary heart disease risk factors could be sustained. We hypothesized that response to MET-diet would not differ by pretreatment body mass index (BMI) classes or =25 to or =30 to or =40 (extremely obese). [table: see text] Metformin-diet was successful in producing stable approximately 8% weight reduction for all 4 years (trend P weight on MET-diet was significant (P or =40, > or =30 to or =25 to weight category (BMI, .1) in the 4 BMI categories. By stepwise regression, weight loss was a significant (P polycystic ovary syndrome effectively and safely reduces weight and LDL-C while raising HDL-C, and maintains these outcomes stable over 4 years.

  7. Perceptual consequences of different signal changes due to binaural noise reduction: do hearing loss and working memory capacity play a role?

    Science.gov (United States)

    Neher, Tobias; Grimm, Giso; Hohmann, Volker

    2014-01-01

    In a previous study, ) investigated whether pure-tone average (PTA) hearing loss and working memory capacity (WMC) modulate benefit from different binaural noise reduction (NR) settings. Results showed that listeners with smaller WMC preferred strong over moderate NR even at the expense of poorer speech recognition due to greater speech distortion (SD), whereas listeners with larger WMC did not. To enable a better understanding of these findings, the main aims of the present study were (1) to explore the perceptual consequences of changes to the signal mixture, target speech, and background noise caused by binaural NR, and (2) to determine whether response to these changes varies with WMC and PTA. As in the previous study, four age-matched groups of elderly listeners (with N = 10 per group) characterized by either mild or moderate PTAs and either better or worse performance on a visual measure of WMC participated. Five processing conditions were tested, which were based on the previously used (binaural coherence-based) NR scheme designed to attenuate diffuse signal components at mid to high frequencies. The five conditions differed in terms of the type of processing that was applied (no NR, strong NR, or strong NR with restoration of the long-term stimulus spectrum) and in terms of whether the target speech and background noise were processed in the same manner or whether one signal was left unprocessed while the other signal was processed with the gains computed for the signal mixture. Comparison across these conditions allowed assessing the effects of changes in high-frequency audibility (HFA), SD, and noise attenuation and distortion (NAD). Outcome measures included a dual-task paradigm combining speech recognition with a visual reaction time (VRT) task as well as ratings of perceived effort and overall preference. All measurements were carried out using headphone simulations of a frontal target speaker in a busy cafeteria. Relative to no NR, strong NR was found

  8. Effect of smokeless tobacco product marketing and use on population harm from tobacco use policy perspective for tobacco-risk reduction.

    Science.gov (United States)

    Kozlowski, Lynn T

    2007-12-01

    This article presents policy perspectives on the marketing of smokeless tobacco products to reduce population harm from tobacco use. Despite consensus that smokeless tobacco products as sold in the United States are less dangerous than cigarettes, there is no consensus on how to proceed. Diverse factions have different policy concerns. While the tobacco industry is exempted from U.S. Food and Drug Administration (FDA) oversight, the pharmaceutical industry whose nicotine replacement therapy (NRT) medicines compete with smokeless tobacco as noncombustible nicotine-delivery systems are regulated by the FDA. Some public health experts support smokeless tobacco use to reduce population harm from tobacco; other public health experts oppose promoting smokeless tobacco for harm reduction. Adult consumers can freely purchase currently-marketed smokeless tobacco products and even more-deadly cigarettes. Concerns with and advantages of smokeless tobacco products are discussed. In that noncombustible medicinal nicotine-delivery systems have been proven to be effective smoking-cessation aids, smokeless tobacco, as another source of psychoactive doses of nicotine, could be used similarly, in a dose-response fashion as a smoking-cessation aid (consistent with FDA principles for evaluating generic versions of drugs). Price measures should be used on tobacco products to make costs to consumers proportional to product health risks (which would make smokeless tobacco much cheaper than cigarettes), and smokeless tobacco should be encouraged as an option for smoking cessation in adult smokers, particularly for those who have failed to stop smoking using NRT or other methods.

  9. A new approach for AC loss reduction in HTS transformer using auxiliary windings, case study: 25 kA HTS current injection transformer

    Science.gov (United States)

    Heydari, Hossein; Faghihi, Faramarz; Aligholizadeh, Reza

    2008-01-01

    AC loss is one of the important parameters in HTS (high temperature superconducting) AC devices. Among the HTS AC power devices, the transformer is an essential part in the electrical power system. The AC losses in an HTS tape depend on the magnetic field. One of the techniques usually adopted to mitigate the unwanted magnetic field is using a system of coils that produce a magnetic field opposite to the incident one, reducing the total magnetic field. In this paper adding two auxiliary windings to the HTS transformer to produce this opposite magnetic field is proposed. The proper use of these auxiliary windings could reduce the leakage flux and, therefore, the AC loss. A mathematical model is used to describe the behaviour of a transformer operating with auxiliary windings, based on the theory of electromagnetic coupled circuits. The influence of the auxiliary windings on the leakage field is studied by the finite element method (FEM) and the AC loss of an HTS transformer was calculated. Also, the simulation results show that employing auxiliary windings will improve the HTS transformer efficiency.

  10. A new approach for AC loss reduction in HTS transformer using auxiliary windings, case study: 25 kA HTS current injection transformer

    International Nuclear Information System (INIS)

    Heydari, Hossein; Faghihi, Faramarz; Aligholizadeh, Reza

    2008-01-01

    AC loss is one of the important parameters in HTS (high temperature superconducting) AC devices. Among the HTS AC power devices, the transformer is an essential part in the electrical power system. The AC losses in an HTS tape depend on the magnetic field. One of the techniques usually adopted to mitigate the unwanted magnetic field is using a system of coils that produce a magnetic field opposite to the incident one, reducing the total magnetic field. In this paper adding two auxiliary windings to the HTS transformer to produce this opposite magnetic field is proposed. The proper use of these auxiliary windings could reduce the leakage flux and, therefore, the AC loss. A mathematical model is used to describe the behaviour of a transformer operating with auxiliary windings, based on the theory of electromagnetic coupled circuits. The influence of the auxiliary windings on the leakage field is studied by the finite element method (FEM) and the AC loss of an HTS transformer was calculated. Also, the simulation results show that employing auxiliary windings will improve the HTS transformer efficiency

  11. A new approach for AC loss reduction in HTS transformer using auxiliary windings, case study: 25 kA HTS current injection transformer

    Energy Technology Data Exchange (ETDEWEB)

    Heydari, Hossein; Faghihi, Faramarz; Aligholizadeh, Reza [Center of Excellence for Power System Automation and Operation, Electrical Engineering Department, Iran University of Science and Technology, Tehran (Iran, Islamic Republic of)

    2008-01-15

    AC loss is one of the important parameters in HTS (high temperature superconducting) AC devices. Among the HTS AC power devices, the transformer is an essential part in the electrical power system. The AC losses in an HTS tape depend on the magnetic field. One of the techniques usually adopted to mitigate the unwanted magnetic field is using a system of coils that produce a magnetic field opposite to the incident one, reducing the total magnetic field. In this paper adding two auxiliary windings to the HTS transformer to produce this opposite magnetic field is proposed. The proper use of these auxiliary windings could reduce the leakage flux and, therefore, the AC loss. A mathematical model is used to describe the behaviour of a transformer operating with auxiliary windings, based on the theory of electromagnetic coupled circuits. The influence of the auxiliary windings on the leakage field is studied by the finite element method (FEM) and the AC loss of an HTS transformer was calculated. Also, the simulation results show that employing auxiliary windings will improve the HTS transformer efficiency.

  12. Snubber reduction

    International Nuclear Information System (INIS)

    Olson, D.E.; Singh, A.K.

    1986-01-01

    Many safety-related piping systems in nuclear power plants have been oversupported. Since snubbers make up a large percentage of the pipe supports or restraints used in a plant, a plant's snubber population is much larger than required to adequately restrain the piping. This has resulted in operating problems and unnecessary expenses for maintenance and inservice inspections (ISIs) of snubbers. This paper presents an overview of snubber reduction, including: the incentives for removing snubbers, a historical perspective on how piping became oversupported, why it is possible to remove snubbers, and the costs and benefits of doing so

  13. A ZVT–ZCT PWM synchronous buck converter with a simple passive auxiliary circuit for reduction of losses and efficiency enhancement

    Directory of Open Access Journals (Sweden)

    S. Shiva Kumar

    2015-06-01

    Full Text Available In this paper, a Zero-Voltage-Transition (ZVT–Zero-Current Transition (ZCT Pulse-width Modulated (PWM synchronous buck converter (SBC, with a simple passive auxiliary circuit is proposed, which reduces the stresses and improves the efficiency by pacifying the conduction losses compared to a traditional PWM converter, typically suitable for photovoltaic applications. The important design feature of ZVT–ZCT PWM SBC converters is placement of resonant components that mollifies the conduction losses. Due to the ZVT–ZCT, the resonant components with low values are used, thereby resulting in the increase of switching frequency. The ZVT–ZCT operation of the proposed converter is presented through theoretical analysis. The characteristics of the proposed converter are verified with the simulation in the PSIM co-simulated with MATLAB/SIMULINK environment and implemented experimentally.

  14. A Formal Approach to the Selection by Minimum Error and Pattern Method for Sensor Data Loss Reduction in Unstable Wireless Sensor Network Communications

    OpenAIRE

    Kim, Changhwa; Shin, DongHyun

    2017-01-01

    There are wireless networks in which typically communications are unsafe. Most terrestrial wireless sensor networks belong to this category of networks. Another example of an unsafe communication network is an underwater acoustic sensor network (UWASN). In UWASNs in particular, communication failures occur frequently and the failure durations can range from seconds up to a few hours, days, or even weeks. These communication failures can cause data losses significant enough to seriously damage...

  15. Fiscal 1999 basic survey report for promotion of joint implementation. Project for overall loss reduction in Myanmar for thermoelectric power during transmission and distribution; 1999 nendo Myanmar koku karyoku sohaiden denryoku sonshitsu sogo teigen project hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    With connection to the clean development mechanism (CDM) taken into consideration, a study is made about achieving greenhouse gas reduction in Myanmar through power generation facility heat efficiency improvement and power loss reduction. Taken up in the study are the Shwedaung power plant, the Mann power plant, and the power transmission system in the Mandalay District. The profitability of thermoelectric power facility improvement is calculated using the financial internal rate of return (FIRR), derivable from the cost of thermoelectric power facility improvement and the convenience to be created thereby, and using the opportunity cost in Myanmar. The result is then subjected to a feasibility study. Most effective for CO2 reduction is the addition or installation of advanced compound cycle power generation facilities which are also excellent in heat efficiency and power generation cost. The FIRR of thermoelectric power facility improvement is 9.4-12.8%, which means the effort is worth investment. Measures for decreasing power loss during transmission include the use of higher voltages, laying of new lines, employment of conductors thicker in size, and the installation of phase modifiers. The economic internal rate of return (EIRR) and FIRR are calculated for the study of feasibility. An analysis covering a 10-year period results in a 20.41% EIRR (exceeding the socially accepted discount rate of 10%) and a 17.56% FIRR (exceeding the general loan interest of 15%), which means that there is feasibility. (NEDO)

  16. Low energy density diet, weight loss maintenance, and risk of cardiovascular disease following a recent weight reduction program: A randomized control trial

    Directory of Open Access Journals (Sweden)

    Golgis Karimi

    2016-01-01

    Full Text Available Background: Little is known about the effects of a low energy dense diet on weight maintenance and cardiovascular risks following a recent weight reduction. Therefore, we assessed if weight maintenance, lipid profiles, and glycemic control differ between low energy density (LED diet and usual diet consumers following a recent weight reduction. Materials and Methods: In this randomized controlled clinical trial study in a parallel design, we recruited 70 patients with the history of weight reduction in the recent 1 year. LED diet contained 30% fat, 15% protein, and 55% carbohydrate was administered to the test group, and a usual diet including 35% fat, 15% protein, and 50% carbohydrate was prescribed to the control group for 7 months. Dietary intake was assessed by using 3 days food records. Biochemical markers and anthropometric measures were done according to the standard protocol. Results: Weight reduced in LED diet consumers compared to usual diet consumers (−0.3 ± 0.2 vs. 1.3 ± 0.4%, P = 0.002. The results was the same regarding waist circumference (−0.4 ± 0.2 vs. 0.3 ± 0.1%, P = 0.004. Fasting blood sugar also decreased in LED diet group (−9.5 ± 0.8 vs. 0.4 ± 1.0%, P = 0.0001. LED diet group had a drop in percent change of their total cholesterol (−0.4 ± 0.5 vs. 2.05 ± 0.4%, P = 0.04 and low-density lipoprotein-cholesterol (4.8 ± 0.9 vs. −0.3 ± 0.9%, P = 0.002. Conclusion: Our findings confirmed beneficial effects of LED diet on attenuating weight regain in subjects with history of recent weight reduction. It might be derived from higher consumption of fruits, vegetables, and fiber among LED diet than usual diet consumers.

  17. Transient produced because of the loss or reduction of the CNA-I UK system cooling capability incompatible with power operation with RELAP5/MOD3

    International Nuclear Information System (INIS)

    Ventura, Mirta A.

    2002-01-01

    The accidental sequences corresponding to the initiating events associated to T15 group are modeled. This group is defined in the Probabilistic Risk Assessment final report. The code used was RELAP5/MOD3. The representative event of the group is the complete loss of UK system, the complementary safety cooling system of the CNA-I. The transient determined from different availability conditions of systems involved in the event is analyzed. Besides the initiating event, the results coming from the event tree heading failures are also studied. Finally, the sequences corresponding to safe shutdown of the plant, and the sequences involved in core damage are determined. (author)

  18. Reduction of radiation-induced vitamin losses by irradiation of food-stuffs at low temperatures and by exclusion of atmospheric oxygen

    International Nuclear Information System (INIS)

    Diehl, J.F.

    1979-01-01

    The protective effect of low temperatures during irradiation on vitamin B 1 and E levels in foods is not abolished by subsequent storage or heating. Egg powder irradiated at 1 Mrad in the presence of air and stored for 4 months at ambient temperature lost 68% of its thiamin content when irradiated at 20 0 C, 33% when irradiated at -30 0 C. Sunflower oil irradiated at 3 Mrad in the presence of air and subsequently heated for 1 hour at 180 0 C lost 98% of its α-tocopherol content when irradiated at 20 0 C, 65% when irradiated at -30 0 C. Exclusion of atmospheric oxygen by packaging under nitrogen reduced the loss of α-tocopherol in irradiated (0.1 Mrad) rolled oats after 8 months of storage from 56 to 5% and the loss of thiamin from 86 to 26%. Vacuum packaging was equally effective during the first 3 months and somewhat less effective during the following 5 months. Packaging under carbon dioxide showed no advantage over packaging in air. Sensory evaluation of rolled oats, raw or cooked, 1 and 3 months after irradiation with 0.1 Mrad indicated no significant quality difference between unirradiated and irradiated samples packaged under nitrogen. (orig.) [de

  19. Reduction of the interlocking potential of sump sieves by corrosion products as consequence of loss-of-coolant accidents; Verminderung des Verblockungspotenzials von Sumpfansaugsieben durch Korrosionsprodukte nach Kuehlmittelverluststoerfaellen

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, Wolfgang; Kryk, Holger [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany). Inst. fuer Fluiddynamik

    2012-11-01

    In German nuclear power plants thermal insulation fragmentation as a consequence of loss-of-coolant accidents have not been identified, but recently significant pressure increase in the sump sieves due to corrosion products have been observed. The corrosion products are released from hot-galvanized steel grids by steam jet fragmentation. It was shown that critical deposition of corrosion products can occur in the long-term process of the accident. The hazard of sieve blocking could be reduced by zinc containing chemicals or an increase of the pH value (to about 6.7). The possibility of disadvantageous consequences of resulting chemical reactions has to be investigated in the future.

  20. A Mobile Phone-Based Health Coaching Intervention for Weight Loss and Blood Pressure Reduction in a National Payer Population: A Retrospective Study.

    Science.gov (United States)

    Mao, Alice Yuqing; Chen, Connie; Magana, Candy; Caballero Barajas, Karla; Olayiwola, J Nwando

    2017-06-08

    The prevalence of obesity and associated metabolic conditions continue to be challenging and costly to address for health care systems; 71% of American adults were overweight, with 35% of men and 40% of women diagnosed with obesity in 2014. Digital health coaching is an innovative approach to decreasing the barriers of cost and accessibility of receiving health coaching for the prevention and management of chronic disease in overweight or obese individuals. To evaluate the early impact of a mobile phone-based health coaching service on weight loss and blood pressure management in a commercially insured population. This was a retrospective study using existing registry data from a pilot commercial collaboration between Vida Health and a large national insurance provider, which enrolled adult members who were overweight (body mass index >25 kg/m2) and able to engage in a mobile phone-based coaching intervention. Participants received 4 months of intensive health coaching via live video, phone, and text message through the Vida Health app. Participants were also provided with a wireless scale, pedometer, and blood pressure cuff. Of the 1012 enrolled, 763 (75.40%) participants had an initial weight upon enrollment and final weight between 3 and 5 months from enrollment; they served as our intervention group. There were 73 participants out of the 1012 (7.21%) who had weight data 4 months prior to and after Vida coaching, who served as the matched-pair control group. Participants in the intervention group lost an average of 3.23% total body weight (TBW) at 4 months of coaching and 28.6% (218/763) intervention participants achieved a clinically significant weight loss of 5% or more of TBW, with an average of 9.46% weight loss in this cohort. In the matched-pair control group, participants gained on average 1.81% TBW in 4 months without Vida coaching and lost, on average, 2.47% TBW after 4 months of Vida coaching, demonstrating a statistically significant difference of 4

  1. A novel Dual Amylin and Calcitonin Receptor Agonist (DACRA), KBP-089, induces weight loss through a reduction in fat, but not lean mass, while improving food preference

    DEFF Research Database (Denmark)

    Gydesen, Sofie; Hjuler, Sara Toftegaard; Freving, Zenia

    2017-01-01

    Background and Purpose Obesity and associated co-morbidities, such as type 2 diabetes and non-alcoholic fatty liver disease, are major health challenges – hence, development of weight loss therapies with the ability to reduce the co-morbidities is key. Experimental Approach The effect of the dual...... amylin and calcitonin receptor agonist (DACRA), KBP-089, on bodyweight, glucose homeostasis, and fatty acid accumulation in liver and muscle tissue, food preference was investigated. Further, we elucidate weight-independent effects of KBP-089 using a weight-matched group. Key Results High fat diet fed...... improved glucose homeostasis through improved insulin action. To obtain a weight-matched group, significantly less food was offered (9% less than in the KBP-089 group). Weight-matching led to improved glucose homeostasis through lowered plasma insulin; however, these were inferior to the effect of KBP-089...

  2. Noise-induced and age-related hearing loss:  new perspectives and potential therapies [version 1; referees: 4 approved

    Directory of Open Access Journals (Sweden)

    M Charles Liberman

    2017-06-01

    Full Text Available The classic view of sensorineural hearing loss has been that the primary damage targets are hair cells and that auditory nerve loss is typically secondary to hair cell degeneration. Recent work has challenged that view. In noise-induced hearing loss, exposures causing only reversible threshold shifts (and no hair cell loss nevertheless cause permanent loss of >50% of the synaptic connections between hair cells and the auditory nerve. Similarly, in age-related hearing loss, degeneration of cochlear synapses precedes both hair cell loss and threshold elevation. This primary neural degeneration has remained a “hidden hearing loss” for two reasons: 1 the neuronal cell bodies survive for years despite loss of synaptic connection with hair cells, and 2 the degeneration is selective for auditory nerve fibers with high thresholds. Although not required for threshold detection when quiet, these high-threshold fibers are critical for hearing in noisy environments. Research suggests that primary neural degeneration is an important contributor to the perceptual handicap in sensorineural hearing loss, and it may be key to the generation of tinnitus and other associated perceptual anomalies. In cases where the hair cells survive, neurotrophin therapies can elicit neurite outgrowth from surviving auditory neurons and re-establishment of their peripheral synapses; thus, treatments may be on the horizon.

  3. Hearing loss

    Science.gov (United States)

    Decreased hearing; Deafness; Loss of hearing; Conductive hearing loss; Sensorineural hearing loss; Presbycusis ... Symptoms of hearing loss may include: Certain sounds seeming too loud Difficulty following conversations when two or more people are talking ...

  4. Return of visual function after bilateral visual loss following flow diversion embolization of a giant ophthalmic aneurysm due to both reduction in mass effect and reduction in aneurysm pulsation.

    Science.gov (United States)

    Patel, Saharsh; Fargen, Kyle M; Peters, Keith; Krall, Peter; Samy, Hazem; Hoh, Brian L

    2015-01-01

    Large and giant paraclinoid aneurysms are challenging to treat by either surgical or endovascular means. Visual dysfunction secondary to optic nerve compression and its relationship with aneurysm size, pulsation and thrombosis is poorly understood. We present a patient with a giant paraclinoid aneurysm resulting in bilateral visual loss that worsened following placement of a Pipeline Embolization Device and adjunctive coiling. Visual worsening occurred in conjunction with aneurysm thrombosis, increase in maximal aneurysm diameter and new adjacent edema. Her visual function spontaneously improved in a delayed fashion to better than pre-procedure, in conjunction with reduced aneurysmal mass effect, size and pulsation artifact on MRI. This report documents detailed ophthalmologic and MRI evidence for the role of thrombosis, aneurysm mass effect and aneurysm pulsation as causative etiologies for both cranial nerve dysfunction and delayed resolution following flow diversion treatment of large cerebral aneurysms. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. Reduction of standby-losses - Obstacles and how to get over them; Verminderung der Standby-Verluste. Hindernisse und Massnahmen zur Ueberwindung

    Energy Technology Data Exchange (ETDEWEB)

    Nipkow, J. [Arena, Zuerich (Switzerland); Togni, G. [Togni Energie GmbH, Zuerich (Switzerland); Braunwalder, A. [Braunwalder Energie-Kommunikation, Erstfeld (Switzerland)

    2007-12-15

    This final report for the Swiss Federal Office of Energy (SFOE) takes a look at how stand-by losses in electrical devices and consumer electronics can be reduced. The project presents an inventory of appliances along with estimates of consumption levels in standby mode. This permitted the authors to identify current priority areas such as consumer electronics, PC workstations and coffee machines. Various tools and measures to be taken are also described, including the implementation of minimum requirements for reducing standby consumption. These are assessed on the basis of a variety of criteria. Implementation measures and projects are proposed that show the greatest potential for success in reducing standby power consumption. A number of implementation projects already initiated while the study was still in progress include the 'Energy City' mouse switching device, the WWF's 'Stop standby' campaign, the 'EnergyBox standby check', hints on PC configuration for standby/sleep mode, the energy-efficient coffee machines promotion campaign, and the 'Topten' list of hi-fi systems with low standby consumption. Base data and modelling methods are reported on, as are measures to be taken.

  6. Recent habitat fragmentation caused by major roads leads to reduction of gene flow and loss of genetic variability in ground beetles.

    Science.gov (United States)

    Keller, Irene; Largiadèr, Carlo R

    2003-02-22

    Although habitat fragmentation is suspected to jeopardize the long-term survival of many species, few data are available on its impact on the genetic variability of invertebrates. We assess the genetic population structure of the flightless ground beetle Carabus violaceus L., 1758 in a Swiss forest, which is divided into several fragments by a highway and two main roads. Eight samples were collected from different forest fragments and analysed at six microsatellite loci. The largest genetic differentiation was observed between samples separated by roads and in particular by the highway. The number of roads between sites explained 44% of the variance in pairwise F(ST) estimates, whereas the age of the road and the geographical distance between locations were not significant factors. Furthermore, a comparison of allelic richness showed that the genetic variability in a small forest fragment isolated by the highway was significantly lower than in the rest of the study area. These findings strongly support the hypothesis that large roads are absolute barriers to gene flow in C. violaceus, which may lead to a loss of genetic variability in fragmented populations.

  7. Impact of Genetic Reduction of NMNAT2 on Chemotherapy-Induced Losses in Cell Viability In Vitro and Peripheral Neuropathy In Vivo.

    Directory of Open Access Journals (Sweden)

    Richard A Slivicki

    Full Text Available Nicotinamide mononucleotide adenylyl transferases (NMNATs are essential neuronal maintenance factors postulated to preserve neuronal function and protect against axonal degeneration in various neurodegenerative disease states. We used in vitro and in vivo approaches to assess the impact of NMNAT2 reduction on cellular and physiological functions induced by treatment with a vinca alkaloid (vincristine and a taxane-based (paclitaxel chemotherapeutic agent. NMNAT2 null (NMNAT2-/- mutant mice die at birth and cannot be used to probe functions of NMNAT2 in adult animals. Nonetheless, primary cortical cultures derived from NMNAT2-/- embryos showed reduced cell viability in response to either vincristine or paclitaxel treatment whereas those derived from NMNAT2 heterozygous (NMNAT2+/- mice were preferentially sensitive to vincristine-induced degeneration. Adult NMNAT2+/- mice, which survive to adulthood, exhibited a 50% reduction of NMNAT2 protein levels in dorsal root ganglia relative to wildtype (WT mice with no change in levels of other NMNAT isoforms (NMNAT1 or NMNAT3, NMNAT enzyme activity (i.e. NAD/NADH levels or microtubule associated protein-2 (MAP2 or neurofilament protein levels. We therefore compared the impact of NMNAT2 knockdown on the development and maintenance of chemotherapy-induced peripheral neuropathy induced by vincristine and paclitaxel treatment using NMNAT2+/- and WT mice. NMNAT2+/- did not differ from WT mice in either the development or maintenance of either mechanical or cold allodynia induced by either vincristine or paclitaxel treatment. Intradermal injection of capsaicin, the pungent ingredient in hot chili peppers, produced equivalent hypersensitivity in NMNAT2+/- and WT mice receiving vehicle in lieu of paclitaxel. Capsaicin-evoked hypersensitivity was enhanced by prior paclitaxel treatment but did not differ in either NMNAT2+/- or WT mice. Thus, capsaicin failed to unmask differences in nociceptive behaviors in either

  8. CO2 loss by permafrost thawing implies additional emissions reductions to limit warming to 1.5 or 2 °C

    Science.gov (United States)

    Burke, Eleanor J.; Chadburn, Sarah E.; Huntingford, Chris; Jones, Chris D.

    2018-02-01

    Large amounts of carbon are stored in the permafrost of the northern high latitude land. As permafrost degrades under a warming climate, some of this carbon will decompose and be released to the atmosphere. This positive climate-carbon feedback will reduce the natural carbon sinks and thus lower anthropogenic CO2 emissions compatible with the goals of the Paris Agreement. Simulations using an ensemble of the JULES-IMOGEN intermediate complexity climate model (including climate response and process uncertainty) and a stabilization target of 2 °C, show that including the permafrost carbon pool in the model increases the land carbon emissions at stabilization by between 0.09 and 0.19 Gt C year-1 (10th to 90th percentile). These emissions are only slightly reduced to between 0.08 and 0.16 Gt C year-1 (10th to 90th percentile) when considering 1.5 °C stabilization targets. This suggests that uncertainties caused by the differences in stabilization target are small compared with those associated with model parameterisation uncertainty. Inertia means that permafrost carbon loss may continue for many years after anthropogenic emissions have stabilized. Simulations suggest that between 225 and 345 Gt C (10th to 90th percentile) are in thawed permafrost and may eventually be released to the atmosphere for stabilization target of 2 °C. This value is 60-100 Gt C less for a 1.5 °C target. The inclusion of permafrost carbon will add to the demands on negative emission technologies which are already present in most low emissions scenarios.

  9. CRP, but not TNF-α or IL-6, decreases after weight loss in patients with morbid obesity exposed to intensive weight reduction and balneological treatment*

    Science.gov (United States)

    Rość, Danuta; Adamczyk, Przemysław; Boinska, Joanna; Szafkowski, Robert; Ponikowska, Irena; Stankowska, Katarzyna; Góralczyk, Barbara; Ruszkowska-Ciastek, Barbara

    2015-01-01

    Objective: The aim of this study was to evaluate the concentrations of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and the degree of homeostasis model assessment-insulin resistance (HOMA-IR) in patients with morbid obesity exposed to a three-week low-calorie diet and balneotherapy. Methods: The study included 33 patients (25 females and 8 males; mean age 46 years) with body mass index (BMI) values of >40 kg/m2. Evaluations of CRP, IL-6, TNF-α, lipid profile, HOMA-IR, and fasting glucose were carried out before (baseline data) and three weeks after the treatment. The control group consisted of 20 healthy volunteers (15 females and 5 males) with a mean age of 39 years and BMI values of ≤24.9 kg/m2. Results: In the blood of patients with morbid obesity we found significantly elevated levels of CRP, TNF-α, triglycerides, HOMA-IR and fasting glucose, but a decreased level of high density lipoprotein (HDL)-cholesterol, compared with the healthy individuals. The treatment resulted in about a 9.4% reduction in body weight from 122.5 to 111.0 kg and a significant decrease in the concentration of CRP, but no change in TNF-α or IL-6. HOMA-IR was significantly reduced. Conclusions: The decrease in CRP level without changes in TNF-α or IL-6 concentrations after the low-calorie diet and balneological treatment, suggests that an essential amount of adipose tissue must be removed before proper adipocyte function is restored. The decrease in HOMA-IR indicates an improvement in insulin sensitivity, which is beneficial in obese patients. PMID:25990058

  10. Economic evaluations of occupational health interventions from a company's perspective: A systematic review of methods to estimate the cost of health-related productivity loss

    NARCIS (Netherlands)

    Uegaki, K.; Bruijne, M.C. de; Beek, A.J. van der; Mechelen, W. van; Tulder, M.W. van

    2011-01-01

    Objectives: To investigate the methods used to estimate the indirect costs of health-related productivity in economic evaluations from a company's perspective. Methods: The primary literature search was conducted in Medline and Embase. Supplemental searches were conducted in the Cochrane NHS

  11. Comparative evaluation of the efficacy of the cyclooxygenase pathway inhibitor and nitric oxide synthase inhibitor in the reduction of alveolar bone loss in ligature induced periodontitis in rats: An experimental study

    Directory of Open Access Journals (Sweden)

    Rekha Jagadish

    2014-01-01

    Full Text Available Background: Alveolar bone loss is the most striking feature of periodontal disease. The aim of this study was to investigate the effect of a cyclooxygenase (COX pathway inhibitor and nitric oxide synthase (NOS inhibitor in the reduction of alveolar bone loss in an experimental periodontal disease (EPD model. Materials and Methods: The study was conducted on 60 Wistar rats divided into three groups of 20 rats each and then subjected to a ligature placement around the left maxillary second molars. Group 1 rats were treated with COX inhibitor (diclofenac sodium 10 mg/kg/d, group 2 with NOS inhibitor (aminoguanidine hydrochloride 10 mg/kg/d and group 3 served as controls, receiving only saline, intraperitoneally 1h before EPD induction and daily until the sacrifice on the 11 th day. Leukogram was performed before ligation, at 6 h and at the first, seventh and 11 th days after EPD induction. After sacrifice, all the excised maxillae were subjected to morphometric and histometric analysis to measure the alveolar bone loss. Histopathological analysis was carried out to estimate cell influx, alveolar bone and cementum integrity. Results: Induction of experimental periodontitis in the rat model produced pronounced leucocytosis, which was significantly reduced by the administration of diclofenac sodium and aminoguanidine on the 11 th day. In morphometric and histometric examinations, both the test drugs significantly (P < 0.05 inhibited the alveolar bone loss as compared with the control group. Conclusion: Both COX inhibitor and NOS inhibitor are equally effective in inhibiting the inflammatory bone resorption in an experimental periodontitis model.

  12. An Investigation of Self-reported Health-related Productivity Loss in Office Workers and Associations With Individual and Work-related Factors Using an Employer's Perspective.

    Science.gov (United States)

    Pereira, Michelle Jessica; Johnston, Venerina; Straker, Leon Melville; Sjøgaard, Gisela; Melloh, Markus; O'Leary, Shaun Patrick; Comans, Tracy Anne

    2017-07-01

    Office workers have a high prevalence of musculoskeletal conditions. This can be a significant economic burden due to health-related productivity loss. Individual and work-related factors related to office worker health-related productivity were investigated. A survey including the Health and Work Performance Questionnaire, which estimated productivity loss, also recorded individual and work-related factors with potential associations with health-related productivity. Muscle function and workstation ergonomics were examined through physical assessments. Linear models investigated the relationships between these factors and health-related productivity. Significant factors identified were occupational category (0.001 productivity loss was greater in office workers working as managers, with lower job satisfaction and psychological wellbeing, and those with musculoskeletal pain. Office worker health-related productivity loss is represented by a combination of both individual and work-related factors.

  13. The experiences of families living with the anticipatory loss of a school-age child with spinal muscular atrophy - the parents' perspectives.

    Science.gov (United States)

    Yang, Bao-Huan; Mu, Pei-Fan; Wang, Wen-Sheng

    2016-09-01

    To probe into parents' anticipatory loss of school-age children with Type I or II spinal muscular atrophy. Spinal muscular atrophy is a rare disorder that causes death. Children die early due to either gradual atrophy or an infection of the lungs. Therefore, family members experience anticipatory loss, which causes grief before the actual loss. Family members feel physically and mentally exhausted, which results in a family crisis. Therefore, it is important to explore their experiences related to anticipatory loss to assist with the adjustment of the families to their circumstances. This study applied a phenomenology method and purposive sampling. The 19 parents who participated in this study were referred to us by two medical centers in Taiwan. Their average age was 32-49 years. Using in-depth interviews, this study explored parents' anticipatory loss. The interviews were recorded and transcribed. Meanings were extracted using Giorgi analysis, and precision was assessed according to Guba and Lincoln, which was treated as the evaluation standard. Four themes were identified from the parents' interviews. The themes included enduring the helplessness and pressure of care, suffering due to the child's rare and unknown condition, loss of hope and a reinforcement of the parent-child attachment, and avoiding the pressure of death and enriching the child's life. The research findings help nurses identify anticipatory loss among parents of school-age children with type I or II spinal muscular atrophy. They enhance health professionals' understanding of the panic that occurs in the society surrounding the families, family members' dynamic relationships, and the families' demands for care. In an attempt to providing intersubjective empathy and support with family having a child with type I and II SMA, nurses may recognize relevant family reactions and enhancing their hope and parent-child attachment. Encourage family members and child go beyond the pressure of death and

  14. Pregnancy Loss

    Science.gov (United States)

    ... To receive Pregnancy email updates Enter email Submit Pregnancy loss Pregnancy loss is a harsh reality faced ... have successful pregnancies. Expand all | Collapse all Why pregnancy loss happens As many as 10 to 15 ...

  15. Emotion regulation reduces loss aversion and decreases amygdala responses to losses.

    Science.gov (United States)

    Sokol-Hessner, Peter; Camerer, Colin F; Phelps, Elizabeth A

    2013-03-01

    Emotion regulation strategies can alter behavioral and physiological responses to emotional stimuli and the neural correlates of those responses in regions such as the amygdala or striatum. The current study investigates the brain systems engaged when using an emotion regulation technique during financial decisions. In decision making, regulating emotion with reappraisal-focused strategies that encourage taking a different perspective has been shown to reduce loss aversion as observed both in choices and in the relative arousal responses to actual loss and gain outcomes. In the current study, we find using fMRI that behavioral loss aversion correlates with amygdala activity in response to losses relative to gains. Success in regulating loss aversion also correlates with the reduction in amygdala responses to losses but not to gains. Furthermore, across both decisions and outcomes, we find the reappraisal strategy increases baseline activity in dorsolateral and ventromedial prefrontal cortex and the striatum. The similarity of the neural circuitry observed to that seen in emotion regulation, despite divergent tasks, serves as further evidence for a role of emotion in decision making, and for the power of reappraisal to change assessments of value and thereby choices.

  16. An Investigation of Self-reported Health-related Productivity Loss in Office Workers and Associations With Individual and Work-related Factors Using an Employer's Perspective

    DEFF Research Database (Denmark)

    Pereira, Michelle Jessica; Johnston, Venerina; Straker, Leon Melville

    2017-01-01

    the Health and Work Performance Questionnaire, which estimated productivity loss, also recorded individual and work-related factors with potential associations with health-related productivity. Muscle function and workstation ergonomics were examined through physical assessments. Linear models investigated...... in office workers working as managers, with lower job satisfaction and psychological wellbeing, and those with musculoskeletal pain. CONCLUSION: Office worker health-related productivity loss is represented by a combination of both individual and work-related factors.......OBJECTIVE: Office workers have a high prevalence of musculoskeletal conditions. This can be a significant economic burden due to health-related productivity loss. Individual and work-related factors related to office worker health-related productivity were investigated. METHODS: A survey including...

  17. Motivation for Weight-Loss Diets: A Clustering, Longitudinal Field Study Using Self-Esteem and Self-Determination Theory Perspectives

    Science.gov (United States)

    Georgiadis, Manolis M.; Biddle, Stuart J. H.; Stavrou, Nektarios A.

    2006-01-01

    Background: Gradual elevation of body weight leads numerous individuals to dieting and weight loss behaviours. Nevertheless, the prevalence of obesity continues to rise in industrialised countries. The examination of the motivational determinants of dietary modification ("dieting") in order to identify clusters of individuals in the…

  18. Spatially Explicit Analysis of Biodiversity Loss Due to Global Agriculture, Pasture and Forest Land Use from a Producer and Consumer Perspective.

    Science.gov (United States)

    Chaudhary, Abhishek; Pfister, Stephan; Hellweg, Stefanie

    2016-04-05

    Anthropogenic land use to produce commodities for human consumption is the major driver of global biodiversity loss. Synergistic collaboration between producers and consumers in needed to halt this trend. In this study, we calculate species loss on 5 min × 5 min grid level and per country due to global agriculture, pasture and forestry by combining high-resolution land use data with countryside species area relationship for mammals, birds, amphibians, and reptiles. Results show that pasture was the primary driver of biodiversity loss in Madagascar, China and Brazil, while forest land use contributed the most to species loss in DR Congo and Indonesia. Combined with the yield data, we quantified the biodiversity impacts of 1 m(3) of roundwood produced in 139 countries, concluding that tropical countries with low timber yield and a large presence of vulnerable species suffer the highest impact. We also calculated impacts per kg for 160 crops grown in different countries and linked it with FAO food trade data to assess the biodiversity impacts embodied in Swiss food imports. We found that more than 95% of Swiss consumption impacts rest abroad with cocoa, coffee and palm oil imports being responsible for majority of damage.

  19. Female pattern hair loss

    Directory of Open Access Journals (Sweden)

    İdil Ünal

    2014-06-01

    Full Text Available Female androgenetic alopecia is the commonest cause of hair loss in women. It is characterized by a diffuse reduction in hair density over the crown and frontal scalp with retention of the frontal hairline and a characteristic pattern distribution in genetically predisposed women. Because of the uncertain relationship with the androgens Female Pattern Hair Loss (FPHL is the most preferred definition of the condition. This review has been focused on the clinical features, diagnosis and treatment alternatives of FPHL.

  20. Improved survival in rhesus macaques immunized with modified vaccinia virus Ankara recombinants expressing simian immunodeficiency virus envelope correlates with reduction in memory CD4+ T-cell loss and higher titers of neutralizing antibody.

    Science.gov (United States)

    Ourmanov, Ilnour; Kuwata, Takeo; Goeken, Robert; Goldstein, Simoy; Iyengar, Ranjani; Buckler-White, Alicia; Lafont, Bernard; Hirsch, Vanessa M

    2009-06-01

    Previous studies demonstrated that immunization of macaques with simian immunodeficiency virus (SIV) Gag-Pol and Env recombinants of the attenuated poxvirus modified vaccinia virus Ankara (MVA) provided protection from high viremia and AIDS following challenge with a pathogenic strain of SIV. Although all animals became infected, plasma viremia was significantly reduced in animals that received the MVA-SIV recombinant vaccines compared with animals that received nonrecombinant MVA. Most importantly, the reduction in viremia resulted in a significant increase in median and cumulative survival. Continued analysis of these animals over the subsequent 9 years has shown that they maintain a survival advantage, although all but two of the macaques have progressed to AIDS. Importantly, improved survival correlated with preservation of memory CD4(+) T cells in the peripheral blood. The greatest survival advantage was observed in macaques immunized with regimens containing SIV Env, and the titer of neutralizing antibodies to the challenge virus prior to or shortly following challenge correlated with preservation of CD4(+) T cells. These data are consistent with a role for neutralizing antibodies in nonsterilizing protection from high viremia and associated memory CD4(+) T-cell loss.

  1. Estimating the Effect and Economic Impact of Absenteeism, Presenteeism, and Work Environment-Related Problems on Reductions in Productivity from a Managerial Perspective.

    Science.gov (United States)

    Strömberg, Carl; Aboagye, Emmanuel; Hagberg, Jan; Bergström, Gunnar; Lohela-Karlsson, Malin

    2017-09-01

    The aim of this study was to propose wage multipliers that can be used to estimate the costs of productivity loss for employers in economic evaluations, using detailed information from managers. Data were collected in a survey panel of 758 managers from different sectors of the labor market. Based on assumed scenarios of a period of absenteeism due to sickness, presenteeism and work environment-related problem episodes, and specified job characteristics (i.e., explanatory variables), managers assessed their impact on group productivity and cost (i.e., the dependent variable). In an ordered probit model, the extent of productivity loss resulting from job characteristics is predicted. The predicted values are used to derive wage multipliers based on the cost of productivity estimates provided by the managers. The results indicate that job characteristics (i.e., degree of time sensitivity of output, teamwork, or difficulty in replacing a worker) are linked to productivity loss as a result of health-related and work environment-related problems. The impact of impaired performance on productivity differs among various occupations. The mean wage multiplier is 1.97 for absenteeism, 1.70 for acute presenteeism, 1.54 for chronic presenteeism, and 1.72 for problems related to the work environment. This implies that the costs of health-related and work environment-related problems to organizations can exceed the worker's wage. The use of wage multipliers is recommended for calculating the cost of health-related and work environment-related productivity loss to properly account for actual costs. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  2. Energy-Saving and Carbon Reduction Effects of Long-Term Green Transportation Policy in Taiwan: International Comparisons and the East Asian Perspective

    OpenAIRE

    CHEN Chiu, Lee-in

    2014-01-01

    Energy-saving and carbon reduction in the transportation industry are becoming important research issues in East Asia. Among various international policy-effect evaluation frameworks, the current study fi rst reviews taxation, pricing, and demand elasticity among car users. Second, it reviews the thinking behind the operation of rail systems, as well as the policies therein, and evaluations of their effi ciency and sustainability. In the United States, developments in train systems that took ...

  3. The ICF Core Sets for hearing loss--researcher perspective. Part I: Systematic review of outcome measures identified in audiological research.

    Science.gov (United States)

    Granberg, Sarah; Dahlström, Jennie; Möller, Claes; Kähäri, Kim; Danermark, Berth

    2014-02-01

    To review the literature in order to identify outcome measures used in research on adults with hearing loss (HL) as part of the ICF Core Sets development project, and to describe study and population characteristics of the reviewed studies. A systematic review methodology was applied using multiple databases. A comprehensive search was conducted and two search pools were created, pool I and pool II. The study population included adults (≥ 18 years of age) with HL and oral language as the primary mode of communication. 122 studies were included. Outcome measures were distinguished by 'instrument type', and 10 types were identified. In total, 246 (pool I) and 122 (pool II) different measures were identified, and only approximately 20% were extracted twice or more. Most measures were related to speech recognition. Fifty-one different questionnaires were identified. Many studies used small sample sizes, and the sex of participants was not revealed in several studies. The low prevalence of identified measures reflects a lack of consensus regarding the optimal outcome measures to use in audiology. Reflections and discussions are made in relation to small sample sizes and the lack of sex differentiation/descriptions within the included articles.

  4. Experiencing Loss

    DEFF Research Database (Denmark)

    Kristiansen, Maria; Younis, Tarek; Hassani, Amani

    2015-01-01

    In this article, we explore how Islam, minority status and refugee experiencesintersect in shaping meaning-making processes following bereavement. We do this througha phenomenological analysis of a biographical account of personal loss told by Aisha, a Muslim Palestinian refugee living in Denmark......, who narrates her experience of losing herhusband to lung cancer. By drawing on a religious framework, Aisha creates meaning fromher loss, which enables her to incorporate this loss into her life history and sustain agency.Her narrative invites wider audiences to witness her tale of overcoming loss...

  5. Memory loss

    Science.gov (United States)

    ... barbiturates or ( hypnotics ) ECT (electroconvulsive therapy) (most often short-term memory loss) Epilepsy that is not well controlled Illness that ... appointment. Medical history questions may include: Type of memory loss, such as short-term or long-term Time pattern, such as how ...

  6. Losses in Ferroelectric Materials

    Science.gov (United States)

    Liu, Gang; Zhang, Shujun; Jiang, Wenhua; Cao, Wenwu

    2015-01-01

    Ferroelectric materials are the best dielectric and piezoelectric materials known today. Since the discovery of barium titanate in the 1940s, lead zirconate titanate ceramics in the 1950s and relaxor-PT single crystals (such as lead magnesium niobate-lead titanate and lead zinc niobate-lead titanate) in the 1980s and 1990s, perovskite ferroelectric materials have been the dominating piezoelectric materials for electromechanical devices, and are widely used in sensors, actuators and ultrasonic transducers. Energy losses (or energy dissipation) in ferroelectrics are one of the most critical issues for high power devices, such as therapeutic ultrasonic transducers, large displacement actuators, SONAR projectors, and high frequency medical imaging transducers. The losses of ferroelectric materials have three distinct types, i.e., elastic, piezoelectric and dielectric losses. People have been investigating the mechanisms of these losses and are trying hard to control and minimize them so as to reduce performance degradation in electromechanical devices. There are impressive progresses made in the past several decades on this topic, but some confusions still exist. Therefore, a systematic review to define related concepts and clear up confusions is urgently in need. With this objective in mind, we provide here a comprehensive review on the energy losses in ferroelectrics, including related mechanisms, characterization techniques and collections of published data on many ferroelectric materials to provide a useful resource for interested scientists and engineers to design electromechanical devices and to gain a global perspective on the complex physical phenomena involved. More importantly, based on the analysis of available information, we proposed a general theoretical model to describe the inherent relationships among elastic, dielectric, piezoelectric and mechanical losses. For multi-domain ferroelectric single crystals and ceramics, intrinsic and extrinsic energy

  7. Losses in Ferroelectric Materials.

    Science.gov (United States)

    Liu, Gang; Zhang, Shujun; Jiang, Wenhua; Cao, Wenwu

    2015-03-01

    Ferroelectric materials are the best dielectric and piezoelectric materials known today. Since the discovery of barium titanate in the 1940s, lead zirconate titanate ceramics in the 1950s and relaxor-PT single crystals (such as lead magnesium niobate-lead titanate and lead zinc niobate-lead titanate) in the 1980s and 1990s, perovskite ferroelectric materials have been the dominating piezoelectric materials for electromechanical devices, and are widely used in sensors, actuators and ultrasonic transducers. Energy losses (or energy dissipation) in ferroelectrics are one of the most critical issues for high power devices, such as therapeutic ultrasonic transducers, large displacement actuators, SONAR projectors, and high frequency medical imaging transducers. The losses of ferroelectric materials have three distinct types, i.e., elastic, piezoelectric and dielectric losses. People have been investigating the mechanisms of these losses and are trying hard to control and minimize them so as to reduce performance degradation in electromechanical devices. There are impressive progresses made in the past several decades on this topic, but some confusions still exist. Therefore, a systematic review to define related concepts and clear up confusions is urgently in need. With this objective in mind, we provide here a comprehensive review on the energy losses in ferroelectrics, including related mechanisms, characterization techniques and collections of published data on many ferroelectric materials to provide a useful resource for interested scientists and engineers to design electromechanical devices and to gain a global perspective on the complex physical phenomena involved. More importantly, based on the analysis of available information, we proposed a general theoretical model to describe the inherent relationships among elastic, dielectric, piezoelectric and mechanical losses. For multi-domain ferroelectric single crystals and ceramics, intrinsic and extrinsic energy

  8. Attribution of irreversible loss to anthropogenic climate change

    Science.gov (United States)

    Huggel, Christian; Bresch, David; Hansen, Gerrit; James, Rachel; Mechler, Reinhard; Stone, Dáithí; Wallimann-Helmer, Ivo

    2016-04-01

    The Paris Agreement (2015) under the UNFCCC has anchored loss and damage in a separate article which specifies that understanding and support should be enhanced in areas addressing loss and damage such as early warning, preparedness, insurance and resilience. Irreversible loss is a special category under loss and damage but there is still missing clarity over what irreversible loss actually includes. Many negative impacts of climate change may be handled or mitigated by existing risk management, reduction and absorption approaches. Irreversible loss, however, is thought to be insufficiently addressed by risk management. Therefore, countries potentially or actually affected by irreversible loss are calling for other measures such as compensation, which however is highly contested in international climate policy. In Paris (2015) a decision was adopted that loss and damage as defined in the respective article of the agreement does not involve compensation and liability. Nevertheless, it is likely that some sort of mechanism will eventually need to come into play for irreversible loss due to anthropogenic climate change, which might involve compensation, other forms of non-monetary reparation, or transformation. Furthermore, climate litigation has increasingly been attempted to address negative effects of climate change. In this context, attribution is important to understand the drivers of change, what counts as irreversible loss due to climate change, and, possibly, who or what is responsible. Here we approach this issue by applying a detection and attribution perspective on irreversible loss. We first analyze detected climate change impacts as assessed in the IPCC Fifth Assessment Report. We distinguish between irreversible loss in physical, biological and human systems, and accordingly identify the following candidates of irreversible loss in these systems: loss of glaciers and ice sheets, loss of subsurface ice (permafrost) and related loss of lake systems; loss

  9. Perspectives on how operation & maintenance (O&M) innovations contribute to the reduction of Levelized Cost of Energy (LCOE) in offshore wind parks

    DEFF Research Database (Denmark)

    Brink, Tove; Madsen, Svend Ole; Lutz, Salla

    2015-01-01

    of regulations across countries, standardization of education, training and support for the alignment of rules and procedures and funding of research and educational activities. In short, the Triple Helix Approach needs to be united – not fragmented as it is now 2. Governance is revealed to be underdeveloped...... in the reduction of LCOE; several joint approaches to the development of the wind park should be introduced. This means focusing on several activities. In short, strategic innovation needs to be open, with a focus on the whole ecosystem of business development - not closed as it is now and with a focus...... on individual and fragmented initiatives on business development. a. Utilization of experience with O&M activities to improve construction, installation and O&M tasks. b. Development of preventive and remote solutions. c. Flexible standards on successful aspects of solutions. d. Qualified and shared IT...

  10. REDUCTIONS WITHOUT REGRET: SUMMARY

    Energy Technology Data Exchange (ETDEWEB)

    Swegle, J.; Tincher, D.

    2013-09-16

    This paper briefly summarizes the series in which we consider the possibilities for losing, or compromising, key capabilities of the U.S. nuclear force in the face of modernization and reductions. The first of the three papers takes an historical perspective, considering capabilities that were eliminated in past force reductions. The second paper is our attempt to define the needed capabilities looking forward in the context of the current framework for force modernization and the current picture of the evolving challenges of deterrence and assurance. The third paper then provides an example for each of our undesirable outcomes: the creation of roach motels, box canyons, and wrong turns.

  11. Weight Loss

    Science.gov (United States)

    ... Rights Employment Discrimination Health Care Professionals Law Enforcement Driver's License For Lawyers Food & Fitness Home Food MyFoodAdvisor ... Fit Types of Activity Weight Loss Assess Your Lifestyle Getting Started Food Choices In My Community Home ...

  12. Lung volume reduction in pulmonary emphysema from the radiologist's perspective; Lungenvolumenreduktion beim Lungenemphysem aus der Sicht des Radiologen

    Energy Technology Data Exchange (ETDEWEB)

    Doellinger, F.; Poellinger, A. [Charite Universitaetsmedizin Berlin (Germany). Dept. of Radiology; Huebner, R.H. [Charite Universitaetsmedizin Berlin (Germany). Dept. of Internal Medicine/Infectious and Respiratory Diseases; Kuhnigk, J.M. [Fraunhofer MEVIS, Bremen (Germany). Inst. for Medical Image Computing

    2015-08-15

    Pulmonary emphysema causes decrease in lung function due to irreversible dilatation of intrapulmonary air spaces, which is linked to high morbidity and mortality. Lung volume reduction (LVR) is an invasive therapeutical option for pulmonary emphysema in order to improve ventilation mechanics. LVR can be carried out by lung resection surgery or different minimally invasive endoscopical procedures. All LVR-options require mandatory preinterventional evaluation to detect hyperinflated dysfunctional lung areas as target structures for treatment. Quantitative computed tomography can determine the volume percentage of emphysematous lung and its topographical distribution based on the lung's radiodensity. Modern techniques allow for lobebased quantification that facilitates treatment planning. Clinical tests still play the most important role in post-interventional therapy monitoring, but CT is crucial in the detection of postoperative complications and foreshadows the method's high potential in sophisticated experimental studies. Within the last ten years, LVR with endobronchial valves has become an extensively researched minimally-invasive treatment option. However, this therapy is considerably complicated by the frequent occurrence of functional interlobar shunts. The presence of ''collateral ventilation'' has to be ruled out prior to valve implantations, as the presence of these extraanatomical connections between different lobes may jeopardize the success of therapy. Recent experimental studies evaluated the automatic detection of incomplete lobar fissures from CT scans, because they are considered to be a predictor for the existence of shunts. To date, these methods are yet to show acceptable results.

  13. Reduction redux.

    Science.gov (United States)

    Shapiro, Lawrence

    2018-04-01

    Putnam's criticisms of the identity theory attack a straw man. Fodor's criticisms of reduction attack a straw man. Properly interpreted, Nagel offered a conception of reduction that captures everything a physicalist could want. I update Nagel, introducing the idea of overlap, and show why multiple realization poses no challenge to reduction so construed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Tackling Energy Loss for High-Efficiency Organic Solar Cells with Integrated Multiple Strategies.

    Science.gov (United States)

    Zuo, Lijian; Shi, Xueliang; Jo, Sae Byeok; Liu, Yun; Lin, Fracis; Jen, Alex K-Y

    2018-04-01

    Limited by the various inherent energy losses from multiple channels, organic solar cells show inferior device performance compared to traditional inorganic photovoltaic techniques, such as silicon and CuInGaSe. To alleviate these fundamental limitations, an integrated multiple strategy is implemented including molecular design, interfacial engineering, optical manipulation, and tandem device construction into one cell. Considering the close correlation among these loss channels, a sophisticated quantification of energy-loss reduction is tracked along with each strategy in a perspective to reach rational overall optimum. A novel nonfullerene acceptor, 6TBA, is synthesized to resolve the thermalization and V OC loss, and another small bandgap nonfullerene acceptor, 4TIC, is used in the back sub-cell to alleviate transmission loss. Tandem architecture design significantly reduces the light absorption loss, and compensates carrier dynamics and thermalization loss. Interfacial engineering further reduces energy loss from carrier dynamics in the tandem architecture. As a result of this concerted effort, a very high power conversion efficiency (13.20%) is obtained. A detailed quantitative analysis on the energy losses confirms that the improved device performance stems from these multiple strategies. The results provide a rational way to explore the ultimate device performance through molecular design and device engineering. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Hidden loss

    DEFF Research Database (Denmark)

    Kieffer-Kristensen, Rikke; Johansen, Karen Lise Gaardsvig

    2013-01-01

    to participate. RESULTS: All children were affected by their parents' ABI and the altered family situation. The children's expressions led the authors to identify six themes, including fear of losing the parent, distress and estrangement, chores and responsibilities, hidden loss, coping and support. The main......PRIMARY OBJECTIVE: The purpose of this study was to listen to and learn from children showing high levels of post-traumatic stress symptoms after parental acquired brain injury (ABI), in order to achieve an in-depth understanding of the difficulties the children face in their everyday lives...... finding indicates that the children experienced numerous losses, many of which were often suppressed or neglected by the children to protect the ill parents. CONCLUSIONS: The findings indicated that the children seemed to make a special effort to hide their feelings of loss and grief in order to protect...

  16. Quantum theory without reduction

    International Nuclear Information System (INIS)

    Cini, Marcello; Levy-Leblond, J.-M.

    1990-01-01

    Quantum theory offers a strange, and perhaps unique, case in the history of science. Although research into its roots has provided important results in recent years, the debate goes on. Some theorists argue that quantum theory is weakened by the inclusion of the so called 'reduction of the state vector' in its foundations. Quantum Theory without Reduction presents arguments in favour of quantum theory as a consistent and complete theory without this reduction, and which is capable of explaining all known features of the measurement problem. This collection of invited contributions defines and explores different aspects of this issue, bringing an old debate into a new perspective, and leading to a more satisfying consensus about quantum theory. (author)

  17. Sharp Reduction in Maximum LEU Fuel Temperatures during Loss of Coolant Accidents in a PBMR DPP-400 core by means of Optimised Placement of Neutron Poisons: Implications for Pu fuel-cycles

    International Nuclear Information System (INIS)

    Serfontein, Dawid E.

    2013-01-01

    The optimisation of the power profiles by means of placing an optimised distribution of neutron poison concentrations in the central reflector resulted in a large reduction in the maximum DLOFC temperature, which may produce far reaching safety and licensing benefits. Unfortunately this came at the expense of losing the ability to execute effective load following. The neutron poisons also caused a large reduction of 22% in the average burn-up of the fuel. Further optimisation is required to counter this reduction in burn-up

  18. Primary culprit for tooth loss!!

    OpenAIRE

    Nuvvula, Sailavanya; Chava, Vijay Kumar; Nuvvula, Sivakumar

    2016-01-01

    Aim: In order to facilitate planning for dental health services and to progress strategies to continue the reduction in tooth loss, it is important to identify the factors that result in such loss. therefore the aim of the study is to investigate the major cause for tooth extraction. Objective: to examine whether the major reason for tooth extraction is dental caries or periodontal disease. Materials and Methods: The study is carried out among the dental practitioners in our district. A quest...

  19. Individual Hearing Loss

    Directory of Open Access Journals (Sweden)

    Sébastien Santurette

    2016-06-01

    Full Text Available It is well-established that hearing loss does not only lead to a reduction of hearing sensitivity. Large individual differences are typically observed among listeners with hearing impairment in a wide range of suprathreshold auditory measures. In many cases, audiometric thresholds cannot fully account for such individual differences, which make it challenging to find adequate compensation strategies in hearing devices. How to characterize, model, and compensate for individual hearing loss were the main topics of the fifth International Symposium on Auditory and Audiological Research (ISAAR, held in Nyborg, Denmark, in August 2015. The following collection of papers results from some of the work that was presented and discussed at the symposium.

  20. Cohort Analysis of a 24-Week Randomized Controlled Trial to Assess the Efficacy of a Novel, Partial Meal Replacement Program Targeting Weight Loss and Risk Factor Reduction in Overweight/Obese Adults.

    Science.gov (United States)

    Brindal, Emily; Hendrie, Gilly A; Taylor, Pennie; Freyne, Jill; Noakes, Manny

    2016-05-04

    Our aim was to design and evaluate a weight-loss program, including a partial meal replacement program, point-of-care testing and face-to-face and smartphone app support, appropriate for delivery in a community pharmacy setting. Overweight or obese adults (n = 146, 71.2% female, 48.18 ± 11.75 years old) were recruited to participate in a 24-week weight loss study and randomised to two app conditions. The dietary intervention was consistent regardless of app. Twelve weeks of clinic appointments with a trained consultant were followed by only app support for an additional 12 weeks. By week 24, retention was 57.5%. There were no differences between app conditions. Based on a cohort analysis of the trial, the mean decrease in weight from baseline to week 24 was 6.43 ± 1.06 kg for males (p < 0.001) and 5.66 ± 0.70 kg for females (p < 0.001). Mixed models also revealed decreases for LDL Cholesterol (-0.13 ± 0.08 mmol/L, nonsignificant), triglycerides (-0.08 ± 0.05 mmol/L, nonsignificant) and an increase in HDL cholesterol (+0.08 ± 0.04 mmol/L, ns) were not significant by week 24. Blood glucose (-0.23 ± 0.08 mmol/L, p = 0.040) and blood pressure (Systolic blood pressure -5.77 ± 1.21 Hg/mm, p < 0.001) were significantly lower at week 24 compared to baseline. Weight loss self-efficacy increased and remained significantly higher than baseline at week 24 (16.85 ± 2.93, p < 0.001). Overall, the program supported participants and was successful in achieving significant weight loss and improvements in health outcomes over 24 weeks.

  1. Reduction corporoplasty.

    Science.gov (United States)

    Hakky, Tariq S; Martinez, Daniel; Yang, Christopher; Carrion, Rafael E

    2015-01-01

    Here we present the first video demonstration of reduction corporoplasty in the management of phallic disfigurement in a 17 year old man with a history sickle cell disease and priapism. Surgical management of aneurysmal dilation of the corpora has yet to be defined in the literature. We preformed bilateral elliptical incisions over the lateral corpora as management of aneurysmal dilation of the corpora to correct phallic disfigurement. The patient tolerated the procedure well and has resolution of his corporal disfigurement. Reduction corporoplasty using bilateral lateral elliptical incisions in the management of aneurysmal dilation of the corpora is a safe an feasible operation in the management of phallic disfigurement.

  2. LOFT data reduction

    International Nuclear Information System (INIS)

    Norman, N.L.

    1975-08-01

    The Loss-of-Fluid Test (LOFT) Facility is an experimental facility built around a ''scaled'' version of a large pressurized water reactor (LPWR). LOFT will be used to run loss-of-coolant experiments (LOCEs) and to acquire the necessary data required ''to evaluate the adequacy and improve the analytical methods currently used to predict the loss-of-coolant accident (LOCA) response of LPWRs'' and ''to identify and investigate any unexpected event(s) or threshold(s) in the response of either the plant or the engineered safety features and develop analytical techniques that adequately describe and account for the unexpected behavior(s)''. During the LOCE this required data will be acquired and recorded in both analog and digital modes. Subsequent to the test the analog data will also be converted to the raw digital mode. This raw digital data will be converted to the desired engineering units using the LOFT Data Reduction System. This system is implemented on the IBM 360/75 and is a part of a commercially available data processing program called MAC/RAN III. The theory of reducing LOFT data to engineering units and the application of the MAC/ RAN III system to accomplish this reduction is given. (auth)

  3. Living with vision loss

    Science.gov (United States)

    Diabetes - vision loss; Retinopathy - vision loss; Low vision; Blindness - vision loss ... of visual aids. Some options include: Magnifiers High power reading glasses Devices that make it easier to ...

  4. Reduction Corporoplasty

    Directory of Open Access Journals (Sweden)

    Tariq S. Hakky

    2015-04-01

    Full Text Available Objective Here we present the first video demonstration of reduction corporoplasty in the management of phallic disfigurement in a 17 year old man with a history sickle cell disease and priapism. Introduction Surgical management of aneurysmal dilation of the corpora has yet to be defined in the literature. Materials and Methods: We preformed bilateral elliptical incisions over the lateral corpora as management of aneurysmal dilation of the corpora to correct phallic disfigurement. Results The patient tolerated the procedure well and has resolution of his corporal disfigurement. Conclusions Reduction corporoplasty using bilateral lateral elliptical incisions in the management of aneurysmal dilation of the corpora is a safe an feasible operation in the management of phallic disfigurement.

  5. [Motivation for weight loss among weight loss treatment participants].

    Science.gov (United States)

    Czeglédi, Edit

    2017-12-01

    Unrealistic expectations about weight goal and about weight loss-related benefits can hinder the effort for a successful long-term weight control. To explore weight loss-related goals and their background among overweight/obese patients. Study sample consisted of patients who participated in the inpatient weight loss treatment in the Lipidological Department of Szent Imre Hospital (n = 339, 19% men). Mean age: 50.2 years (SD = 13.47 years), mean BMI: 38.6 (SD = 7.58). self-reported anthropometric data, type and number of treated illnesses, Goals and Relative Weights Questionnaire, Motivations for Weight Loss Scale, Body Shape Questionnaire. Participants would feel disappointed with a possible 10% weight loss in a half-year time span. The acceptable weight loss percentage was higher among women, younger participants and among those who had more excess weight. Motivation regarding the increase in social desirability by weight loss is in association with body dissatisfaction, health related motivation is in association with the number of treated illnesses. Our results are contributing to the understanding of motivational factors behind weight reduction efforts, considering these can improve treatment success rates. Orv Hetil. 2017; 158(49): 1960-1967.

  6. Hair Loss (Alopecia)

    Science.gov (United States)

    ... care Kids’ zone Video library Find a dermatologist Hair loss Overview Hereditary hair loss: Millions of men ... of hair loss can often be successfully treated. Hair loss: Overview Also called alopecia (al-o-PEE- ...

  7. Sociological Perspectives.

    Science.gov (United States)

    Townley, Charles; Middleton, Mike

    This monograph examines sociological perspectives and their applications. It is intended to help the college student coming to sociology for the first time to recognize that there are several perspectives within sociology and to disentangle the mass of terms associated with each. The first distinctive sociological perspective came from the work of…

  8. Risk assessment methodologies for predicting phosphorus losses

    NARCIS (Netherlands)

    Schoumans, O.F.; Chardon, W.J.

    2003-01-01

    Risk assessment parameters are needed to assess the contribution of phosphorus (P) losses from soil to surface water, and the effectiveness of nutrient and land management strategies for the reduction of P loss. These parameters need to take into account the large temporal and spatial variation in P

  9. Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice

    Directory of Open Access Journals (Sweden)

    Melariri P

    2015-02-01

    Full Text Available Paula Melariri,1 Lonji Kalombo,2 Patric Nkuna,2 Admire Dube,2,3 Rose Hayeshi,2 Benhards Ogutu,4,5 Liezl Gibhard,6 Carmen deKock,6 Peter Smith,6 Lubbe Wiesner,6 Hulda Swai2 1Polymers and Composites, Material Science and Manufacturing, Council for Scientific and Industrial Research, Port Elizabeth, South Africa; 2Polymer and Composites, Material Science and Manufacturing, Council for Scientific and Industrial Research, Pretoria, South Africa; 3School of Pharmacy, University of the Western Cape, Bellville, South Africa; 4Centre for Research in Therapeutic Sciences, Strathmore University, Nairobi, Kenya; 5Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya; 6Division of Pharmacology, University of Cape Town Medical School, Groote Schuur Hospital, Cape Town, South Africa Abstract: Tafenoquine (TQ, a new synthetic analog of primaquine, has relatively poor bioavailability and associated toxicity in glucose-6-phosphate dehydrogenase (G6PD-deficient individuals. A microemulsion formulation of TQ (MTQ with sizes <20 nm improved the solubility of TQ and enhanced the oral bioavailability from 55% to 99% in healthy mice (area under the curve 0 to infinity: 11,368±1,232 and 23,842±872 min·µmol/L for reference TQ and MTQ, respectively. Average parasitemia in Plasmodium berghei-infected mice was four- to tenfold lower in the MTQ-treated group. In vitro antiplasmodial activities against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum indicated no change in half maximal inhibitory concentration, suggesting that the microemulsion did not affect the inherent activity of TQ. In a humanized mouse model of G6PD deficiency, we observed reduction in toxicity of TQ as delivered by MTQ at low but efficacious concentrations of TQ. We hereby report an enhancement in the solubility, bioavailibility, and efficacy of TQ against blood stages of Plasmodium parasites without a corresponding increase in toxicity

  10. X-ray emission reduction and photon dose lowering by energy loss of fast electrons induced by return current during the interaction of a short-pulse high-intensity laser on a metal solid target

    Science.gov (United States)

    Compant La Fontaine, A.

    2018-04-01

    During the interaction of a short-pulse high-intensity laser with the preplasma produced by the pulse's pedestal in front of a high-Z metal solid target, high-energy electrons are produced, which in turn create an X-ray source by interacting with the atoms of the converter target. The current brought by the hot electrons is almost completely neutralized by a return current j → driven by the background electrons of the conductive target, and the force exerted on the hot electrons by the electric field E → which induces Ohmic heating j → .E → , produced by the background electrons, reduces the energy of the hot electrons and thus lowers the X-ray emission and photon dose. This effect is analyzed here by means of a simple 1-D temperature model which contains the most significant terms of the relativistic Fokker-Planck equation with electron multiple scattering, and the energy equations of ions, hot, and cold electrons are then solved numerically. This Ohmic heating energy loss fraction τOh is introduced as a corrective term in an improved photon dose model. For instance, for a ps laser pulse with 10 μm spot size, the dose obtained with a tantalum target is reduced by less than about 10% to 40% by the Ohmic heating, depending upon the plasma scale length, target thickness, laser parameters, and in particular its spot size. The laser and plasma parameters may be optimized to limit the effect of Ohmic heating, for instance at a small plasma scale length or small laser spot size. Conversely, others regimes not suitable for dose production are identified. For instance, the resistive heating is enhanced in a foam target or at a long plasma scale length and high laser spot size and intensity, as the mean emission angle θ0 of the incident hot electron bunch given by the ponderomotive force is small; thus, the dose produced by a laser interacting in a gas jet may be inhibited under these circumstances. The resistive heating may also be maximized in order to reduce

  11. Redução de perdas pós-colheita em tomate de mesa acondicionado em três tipos de caixas Reduction of tomato post-harvest losses stored in three different types of boxes

    Directory of Open Access Journals (Sweden)

    Rita Fátima A. Luengo

    2001-07-01

    was significantly different and lower in the Embrapa box, reducing post-harvest losses in tomato fruits.

  12. Ecological interactions drive evolutionary loss of traits.

    Science.gov (United States)

    Ellers, Jacintha; Kiers, E Toby; Currie, Cameron R; McDonald, Bradon R; Visser, Bertanne

    2012-10-01

    Loss of traits can dramatically alter the fate of species. Evidence is rapidly accumulating that the prevalence of trait loss is grossly underestimated. New findings demonstrate that traits can be lost without affecting the external phenotype, provided the lost function is compensated for by species interactions. This is important because trait loss can tighten the ecological relationship between partners, affecting the maintenance of species interactions. Here, we develop a new perspective on so-called `compensated trait loss' and how this type of trait loss may affect the evolutionary dynamics between interacting organisms. We argue that: (1) the frequency of compensated trait loss is currently underestimated because it can go unnoticed as long as ecological interactions are maintained; (2) by analysing known cases of trait loss, specific factors promoting compensated trait loss can be identified and (3) genomic sequencing is a key way forwards in detecting compensated trait loss. We present a comprehensive literature survey showing that compensated trait loss is taxonomically widespread, can involve essential traits, and often occurs as replicated evolutionary events. Despite its hidden nature, compensated trait loss is important in directing evolutionary dynamics of ecological relationships and has the potential to change facultative ecological interactions into obligatory ones. © 2012 Blackwell Publishing Ltd/CNRS.

  13. Economic Loss Caused by GMOs in Denmark

    DEFF Research Database (Denmark)

    Ulfbeck, Vibe Garf

    2008-01-01

    This book presents how European jurisdictions currently respond to economic losses caused by the admixture of gentically modified crops with conventional or organic crops and what alternatives there are from a comparative perspective. Country reports from most European countries are complemented ...

  14. Climate policy: Transparency for Loss and Damage

    Science.gov (United States)

    Mechler, Reinhard

    2017-10-01

    Loss and Damage (L&D) has been gaining traction since the Paris Agreement took the issue on as a separate article, arguably creating a third pillar of international climate policy. Debate so far has led to vague definitions of the remit of the L&D mechanism; research on actor perspectives may help to propel this discourse forward.

  15. Female pattern hair loss

    Directory of Open Access Journals (Sweden)

    Archana Singal

    2013-01-01

    Full Text Available Female pattern hair loss (FPHL is a common cause of hair loss in women characterized by diffuse reduction in hair density over the crown and frontal scalp with retention of the frontal hairline. Its prevalence increases with advancing age and is associated with significant psychological morbidity. The pathophysiology of FPHL is still not completely understood and seems to be multifactorial. Although androgens have been implicated, the involvement of androgen-independent mechanisms is evident from frequent lack of clinical or biochemical markers of hyperandrogenism in affected women. The role of genetic polymorphisms involving the androgen and estrogen receptors is being increasingly recognized in its causation and predicting treatment response to anti-androgens. There are different clinical patterns and classifications of FPHL, knowledge of which facilitates patient management and research. Chronic telogen effluvium remains as the most important differential diagnosis. Thorough history, clinical examination, and evaluation are essential to confirm diagnosis. Patients with clinical signs of androgen excess require assessment of biochemical parameters and imaging studies. It is prudent to screen the patients for metabolic syndrome and cardiovascular risk factors. The treatment comprises medical and/or surgical modalities. Medical treatment should be initiated early as it effectively arrests hair loss progression rather than stimulating regrowth. Minoxidil continues to be the first line therapy whereas anti-androgens form the second line of treatment. The progressive nature of FPHL mandates long-term treatment for sustained effect. Medical therapy may be supplemented with cosmetic concealment in those desirous of greater hair density. Surgery may be worthwhile in some carefully selected patients.

  16. Radon reduction

    International Nuclear Information System (INIS)

    Hamilton, M.A.

    1990-01-01

    During a radon gas screening program, elevated levels of radon gas were detected in homes on Mackinac Island, Mich. Six homes on foundations with crawl spaces were selected for a research project aimed at reducing radon gas concentrations, which ranged from 12.9 to 82.3 pCi/l. Using isolation and ventilation techniques, and variations thereof, radon concentrations were reduced to less than 1 pCi/l. This paper reports that these reductions were achieved using 3.5 mil cross laminated or 10 mil high density polyethylene plastic as a barrier without sealing to the foundation or support piers, solid and/or perforated plastic pipe and mechanical fans. Wind turbines were found to be ineffective at reducing concentrations to acceptable levels. Homeowners themselves installed all materials

  17. Lung volume reduction in chronic obstructive pulmonary disease ...

    African Journals Online (AJOL)

    Lung volume reduction in chronic obstructive pulmonary disease. ... loss to improve pulmonary mechanics and compliance, thereby reducing the work of breathing. ... of obtaining similar functional advantages to surgical lung volume reduction, ...

  18. Understanding Grief and Loss

    Science.gov (United States)

    ... the process of adapting to life after a loss. It is influenced by each person’s society, culture, and religion. Bereavement is the state of having experienced a loss. Common grief reactions Reactions to loss are called ...

  19. Risk Factors for Osteoporosis and Oral Bone Loss in Postmenopausal Women

    National Research Council Canada - National Science Library

    Wactawski-Wende, Jean

    2000-01-01

    ... and oral bone loss, periodontal disease and tooth loss. We hypothesize that reduction in bone density leading to osteoporosis, plays a significant role in increasing susceptibility to destructive periodontitis and tooth loss...

  20. Risk Factors for Osteoporosis and Oral Bone Loss in Postmenopausal Women

    National Research Council Canada - National Science Library

    Wactawski-Wende, Jean

    1999-01-01

    ... and oral bone loss, periodontal disease and tooth loss. We hypothesize that reduction in bone density leading to osteoporosis, plays a significant role in increasing susceptibility to destructive periodontitis and tooth loss...

  1. Risk Factors for Osteoporosis and Oral Bone Loss in Postmenopausal Women

    National Research Council Canada - National Science Library

    Wactawski-Wende, Jean

    2001-01-01

    ... and oral bone loss, periodontal disease and tooth loss. We hypothesize that reduction in bone density leading to osteoporosis, plays a significant role in increasing susceptibility to destructive periodontitis and tooth loss...

  2. Risk Factors for Osteoporosis and Oral Bone Loss in Postmenopausal Women

    National Research Council Canada - National Science Library

    Wacawski-Wende, Jean

    1997-01-01

    ... and oral bone loss, periodontal disease and tooth loss. We hypothesize that reduction in bone density leading to osteoporosis, plays a significant role in increasing susceptibility to destructive periodontitis and tooth loss...

  3. Risk Factors for Osteoporosis and Oral Bone Loss in Postmenopausal Women

    National Research Council Canada - National Science Library

    Wactawski-Wende, Jean

    1998-01-01

    ... and oral bone loss, periodontal disease and tooth loss. We hypothesize that reduction in bone density leading to osteoporosis, plays a significant role in increasing susceptibility to destructive periodontitis and tooth loss...

  4. The effect of accountability on loss aversion.

    Science.gov (United States)

    Vieider, Ferdinand M

    2009-09-01

    This paper investigates the effect of accountability-the expectation on the side of the decision maker of having to justify his/her decisions to somebody else-on loss aversion. Loss aversion is commonly thought to be the strongest component of risk aversion. Accountability is found to reduce the bias of loss aversion. This effect is explained by the higher cognitive effort induced by accountability, which triggers a rational check on emotional reactions at the base of loss aversion, leading to a reduction of the latter. Connections to dual-processing models are discussed.

  5. Economic Loan Loss Provision and Expected Loss

    Directory of Open Access Journals (Sweden)

    Stefan Hlawatsch

    2010-10-01

    Full Text Available The intention of a loan loss provision is the anticipation of the loan's expected losses by adjusting the book value of the loan. Furthermore, this loan loss provision has to be compared to the expected loss according to Basel II and, in the case of a difference, liable equity has to be adjusted. This however assumes that the loan loss provision and the expected loss are based on a similar economic rationale, which is only valid conditionally in current loan loss provisioning methods according to IFRS. Therefore, differences between loan loss provisions and expected losses should only result from different approaches regarding the parameter estimation within each model and not due to different assumptions regarding the outcome of the model. The provisioning and accounting model developed in this paper overcomes the before-mentioned shortcomings and is consistent with an economic rationale of expected losses. Additionally, this model is based on a close-to-market valuation of the loan that is in favor of the basic idea of IFRS. Suggestions for changes in current accounting and capital requirement rules are provided.

  6. Unfavourable results following reduction mammoplasty

    Directory of Open Access Journals (Sweden)

    Lakshmi Saleem

    2013-01-01

    Full Text Available Breast reduction is a common cosmetic surgical procedure. It aims not only at bringing down the size of the breast proportionate to the build of the individual, but also to overcome the discomfort caused by massive, ill-shaped and hanging breasts. The operative procedure has evolved from mere reduction of breast mass to enhanced aesthetic appeal with a minimum of scar load. The selection of technique needs to be individualised. Bilateral breast reduction is done most often. Haematoma, seroma, fat necrosis, skin loss, nipple loss and unsightly, painful scars can be the complications of any procedure on the breast. These may result from errors in judgement, wrong surgical plan and imprecise execution of the plan. Though a surfeit of studies are available on breast reduction, very few dwell upon its complications. The following article is a distillation of three decades of experience of the senior author (L.S. in reduction mammoplasty. An effort is made to understand the reasons for unfavourable results. To conclude, most complications can be overcome with proper selection of procedure for the given patient and with gentle tissue handling.

  7. Outage time reduction in GKN II without loss of safety

    International Nuclear Information System (INIS)

    Sturm, J.

    1999-01-01

    GKN II is a 1340 MWE 4-loop pressurised water reactor from Siemens KONVOI type, located in the south of Germany. It was originally connected to the grid at the end of 1988. Commercial operation under utility responsibility started at the second half of 1989. The first outage was performed in 1990. Beginning from this date, the outage duration was contiguously reduced from 33 days to 15 days in 1996. In 1998, two refueling and maintenance outages were performed, each with a duration of 7 days. Key planning factors to achieve these results are: A well adapted planning organisation with an outage manager and an outage planning team. An effective long term planning. This means the combination of work with a long duration every 4 or 8 years. No longlasting work in the years in between. Main work only on one safety train per year. Optimisation and standardisation of the shutdown and the startup sequence. The real change of reactor states have been modified, compared to the vendor recommendations. An tests are assigned to plant conditions, where they are most effective and are less time critical. Small modifications in the plant, mainly on the auxiliary systems, to speedup some sequences. Extreme detailed planning of maintenance and periodic tests. Each work/test can be found in a detailed schedule with a dedicated time widow. Optimized tools to perform the detailed planning and to implement the feedback of experience from former outages. Optimized tools for maintenance and handlings of heavy equipment on the critical path. Optimized tools to perform periodic tests. Key factors during outage are: Permanent control of the schedules with an updated 3-day program. Best and permanent information with this 3-day program of all people that are involved. Fast reaction on delays. Outage managers permanent on site. Gain in safety during shutdown states, with reduced outage duration: It has to be proven, that short outages don't lead to faster and less accurate work. It can be assumed, that shorter outages are even a gain in safety. No single maintenance work is reduced in duration. The effective long term planning allows, even in short outages, a long time window for the main maintenance safety train. The effective detailed planning discovers all safety critical work and avoids agglomeration of tasks at a certain period. Good overview of all works by the outage management during the whole outage. No works on safety trains under midloop conditions. The work on operational systems during these phases is checked in detail for having no influence on the residual heat removal. Highly motivated staff with a vision. The end of the outage is visible. (author)

  8. 国有多元化集团基于税会视角下的潜亏治理问题创新研究%The Innovation of the Potential Loss Management Based on the Perspective of the State Owned Diversified Group

    Institute of Scientific and Technical Information of China (English)

    任丽瑛

    2015-01-01

    The potential loss is the enterprise information distortion of accounting statements in a form,potential loss and no actual reference value,and it can not be used as the basis for business decisions, so there is potential loss phenomenon for enterprises damage is very large,through the state-owned diversified group tax from the perspective of the potential loss of governance the problem is based on the analysis and research, put forward to control internal defects,improve the sustainable development ability of enterprises,enterprises are facing financial problems on the cultivation of professional,in-house team,establish and improve the accounting system of internal department and the establishment of risk warning mechanism of latent losses governance proposals,in order to state-owned enterprises' potential loss problem killed in the root.%潜亏是目前企业会计报表信息失真中的一个表现形式,潜亏并没有实际的参考价值,而且它也不能作为企业决策的依据,所以说存在潜亏现象对于企业来说危害非常大,通过针对国有多元化集团基于税会视角下的潜亏治理问题进行分析和研究,提出了及时控制企业内部缺陷,提升企业的可持续发展能力,警惕企业面临的财务问题,培养专业的内部团队,建立完善的会计电算化内部制度以及建立风险预警机制等潜亏治理建议,以期将国有企业潜亏问题扼杀在根源中。

  9. Hair loss in women.

    Science.gov (United States)

    Harfmann, Katya L; Bechtel, Mark A

    2015-03-01

    Hair loss is a common cause of morbidity for many women. As a key member of the woman's health care team, the obstetrician/gynecologist may be the first person to evaluate the complaint of hair loss. Common types of nonscarring hair loss, including female pattern hair loss and telogen effluvium, may be diagnosed and managed by the obstetrician/gynecologist. A systematic approach to diagnosis and management of these common forms of hair loss is presented.

  10. Weight loss in obese women - exercise v. dietary education ...

    African Journals Online (AJOL)

    Weight loss, body fat loss (%) and daily energy intake reductions were equally reduced in the subjects in all three groups who completed the programme. There was, however, a significantly higher dropout rate in the control group. Taking this into account, the weight loss in the two test groups was similar and greater than ...

  11. Prejudice Reduction in University Programs for Older Adults

    Science.gov (United States)

    Castillo, Jose-Luis Alvarez; Camara, Carmen Palmero; Eguizabal, Alfredo Jimenez

    2011-01-01

    The present paper, drawing from the perspective of social cognition, examines and evaluates an intervention based on social-cognitive perspective-taking on the reduction of stereotyping and prejudice in older adults. Data were collected in a sample of Spanish participants with a mean age of 63.2 years. The intervention, aimed at reducing prejudice…

  12. PREGNANCY LOSS IN MARES

    Directory of Open Access Journals (Sweden)

    Tibary A

    2015-12-01

    Full Text Available Pregnancy loss is an important aspect of equine practice due to the economic and emotional loss that it engenders. Pregnancy loss is often divided in two categories: early pregnancy loss (EPL or embryonic death (ED (first 42 days and fetal losses (after 42 days. Diagnosis of the causes of pregnancy loss is often very challenging. Many of the causes of EPL remain poorly documented but studies on embryo development and embryo-uterine interaction have been able to shed some light on predisposing factors. Fetal losses or abortions are dominated by infectious causes and particularly bacterial placentitis. Detailed reviews of pregnancy loss were recently published by the authors (Tibary et al., 2012; Tibary and Pearson, 2012; Tibary et al., 2014. The objective of this paper is to provide an overview of the epidemiology, etiology, diagnosis and prevention of pregnancy loss in the mare.

  13. Corona helps curb losses

    Energy Technology Data Exchange (ETDEWEB)

    Laasonen, M.; Lahtinen, M.; Lustre, L.

    1996-11-01

    The greatest power losses in electricity transmission arise through a phenomenon called load losses. Corona losses caused by the surface discharge of electricity also constitute a considerable cost item. IVS, the nationwide network company, is investigating corona- induced losses, and has also commissioned similar research from IVO International, the Technical Research Centre of Finland (VTT) and from Tampere University of Technology. The research work strives to gain more in-depth knowledge on the phenomenon of frosting and its impact on corona losses. The correct prediction of frost helps reduce corona losses, while also cutting costs considerably. (orig.)

  14. Telogen Effluvium Hair Loss

    Science.gov (United States)

    ... Category: Share: Yes No, Keep Private Telogen Effluvium Hair Loss Share | It is normal to lose up to ... months after the "shock". This sudden increase in hair loss, usually described as the hair coming out in ...

  15. Recurrent pregnancy loss

    DEFF Research Database (Denmark)

    Egerup, P; Kolte, A M; Larsen, E C

    2016-01-01

    STUDY QUESTION: Is there a different prognostic impact for consecutive and non-consecutive early pregnancy losses in women with secondary recurrent pregnancy loss (RPL)? SUMMARY ANSWER: Only consecutive early pregnancy losses after the last birth have a statistically significant negative prognostic...... impact in women with secondary RPL. WHAT IS KNOWN ALREADY: The risk of a new pregnancy loss increases with the number of previous pregnancy losses in patients with RPL. Second trimester losses seem to exhibit a stronger negative impact than early losses. It is unknown whether the sequence of pregnancy...... losses plays a role for the prognosis in patients with a prior birth. STUDY DESIGN, SIZE, DURATION: This retrospective cohort study of pregnancy outcome in patients with unexplained secondary RPL included in three previously published, Danish double-blinded placebo-controlled trials of intravenous...

  16. Genes and Hearing Loss

    Science.gov (United States)

    ... ENTCareers Marketplace Find an ENT Doctor Near You Genes and Hearing Loss Genes and Hearing Loss Patient ... mutation may only have dystopia canthorum. How Do Genes Work? Genes are a road map for the ...

  17. Menopause and Bone Loss

    Science.gov (United States)

    Fact Sheet & Menopause Bone Loss How are bone loss and menopause related? Throughout life your body keeps a balance between the ... lose bone faster than it can be replaced. Menopause—the time when menstrual periods end, which usually ...

  18. OI Issues: Hearing Loss

    Science.gov (United States)

    ... signals normally to the brain. In addition, hearing losses are classified according to the degree of severity: • Mild, • Moderate, • Severe, • Profound. Hearing losses are also classified according to the sound frequency ...

  19. Early Pregnancy Loss

    Science.gov (United States)

    ... go on to have successful pregnancies. Repeated pregnancy losses are rare. Testing and evaluation can be done ... find a cause if you have several pregnancy losses. Even if no cause is found, most couples ...

  20. Occupational hearing loss

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/001048.htm Occupational hearing loss To use the sharing features on this page, please enable JavaScript. Occupational hearing loss is damage to the inner ear from noise ...

  1. Pregnancy Loss and Miscarriage

    Science.gov (United States)

    ... D linked to miscarriage among women with prior pregnancy loss Release: Anti-HIV drug combination does not increase preterm birth risk, study suggests Release: Elevated blood pressure before pregnancy may increase chance of pregnancy loss All related ...

  2. Coping with Memory Loss

    Science.gov (United States)

    ... Consumers Home For Consumers Consumer Updates Coping With Memory Loss Share Tweet Linkedin Pin it More sharing ... be evaluated by a health professional. What Causes Memory Loss? Anything that affects cognition—the process of ...

  3. Weight Loss Surgery

    Science.gov (United States)

    Weight loss surgery helps people with extreme obesity to lose weight. It may be an option if you cannot lose weight ... obesity. There are different types of weight loss surgery. They often limit the amount of food you ...

  4. Myopic loss aversion revisited

    OpenAIRE

    Blavatskyy, Pavlo; Pogrebna, Ganna

    2009-01-01

    In this paper we reexamine several experimental papers on myopic loss aversion by analyzing individual rather than aggregate choice patterns. We find that the behavior of the majority of subjects is inconsistent with the hypothesis of myopic loss aversion.

  5. Help! It's Hair Loss!

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Hair Loss KidsHealth / For Kids / Hair Loss What's in this ... head are in the resting phase. What Causes Hair Loss? Men, especially older men, are the ones who ...

  6. Proven Weight Loss Methods

    Science.gov (United States)

    Fact Sheet Proven Weight Loss Methods What can weight loss do for you? Losing weight can improve your health in a number of ways. It can lower ... at www.hormone.org/Spanish . Proven Weight Loss Methods Fact Sheet www.hormone.org

  7. Energy losses in switches

    International Nuclear Information System (INIS)

    Martin, T.H.; Seamen, J.F.; Jobe, D.O.

    1993-01-01

    The authors experiments show energy losses between 2 and 10 times that of the resistive time predictions. The experiments used hydrogen, helium, air, nitrogen, SF 6 polyethylene, and water for the switching dielectric. Previously underestimated switch losses have caused over predicting the accelerator outputs. Accurate estimation of these losses is now necessary for new high-efficiency pulsed power devices where the switching losses constitute the major portion of the total energy loss. They found that the switch energy losses scale as (V peak I peak ) 1.1846 . When using this scaling, the energy losses in any of the tested dielectrics are almost the same. This relationship is valid for several orders of magnitude and suggested a theoretical basis for these results. Currents up to .65 MA, with voltages to 3 MV were applied to various gaps during these experiments. The authors data and the developed theory indicates that the switch power loss continues for a much longer time than the resistive time, with peak power loss generally occurring at peak current in a ranging discharge instead of the early current time. All of the experiments were circuit code modeled after developing a new switch loss version based on the theory. The circuit code predicts switch energy loss and peak currents as a function of time. During analysis of the data they noticed slight constant offsets between the theory and data that depended on the dielectric. They modified the plasma conductivity for each tested dielectric to lessen this offset

  8. Beam Loss in Linacs

    CERN Document Server

    Plum, M.A.

    2016-01-01

    Beam loss is a critical issue in high-intensity accelerators, and much effort is expended during both the design and operation phases to minimize the loss and to keep it to manageable levels. As new accelerators become ever more powerful, beam loss becomes even more critical. Linacs for H- ion beams, such as the one at the Oak Ridge Spallation Neutron Source, have many more loss mechanisms compared to H+ (proton) linacs, such as the one being designed for the European Spallation Neutron Source. Interesting H- beam loss mechanisms include residual gas stripping, H+ capture and acceleration, field stripping, black-body radiation and the recently discovered intra-beam stripping mechanism. Beam halo formation, and ion source or RF turn on/off transients, are examples of beam loss mechanisms that are common for both H+ and H- accelerators. Machine protection systems play an important role in limiting the beam loss.

  9. Finding optimal exact reducts

    KAUST Repository

    AbouEisha, Hassan M.

    2014-01-01

    The problem of attribute reduction is an important problem related to feature selection and knowledge discovery. The problem of finding reducts with minimum cardinality is NP-hard. This paper suggests a new algorithm for finding exact reducts

  10. Breast Reduction Surgery

    Science.gov (United States)

    ... considering breast reduction surgery, consult a board-certified plastic surgeon. It's important to understand what breast reduction surgery entails — including possible risks and complications — as ...

  11. Low ac loss geometries in YBCO coated conductors

    International Nuclear Information System (INIS)

    Duckworth, R.C.; List, F.A.; Paranthaman, M.P.; Rupich, M.W.; Zhang, W.; Xie, Y.Y.; Selvamanickam, V.

    2007-01-01

    Reduction of ac losses in applied ac fields can be accomplished through either the creation of filaments and bridging in YBCO coated conductors or by an assembly of narrow width YBCO tapes. The ac losses for each of these geometries were measured at 77 K in perpendicular ac fields up to 100 mT. Despite physical isolation of the filaments, coupling losses were still present in the samples when compared to the expected hysteretic loss. In addition to filamentary conductors the assembly of stacked YBCO conductor provides an alternative method of ac loss reduction. When compared to a 4-mm wide YBCO coated conductor with a critical current of 60 A, the ac loss in a stack of 2-mm wide YBCO coated conductors with a similar total critical current was reduced. While the reduction in ac loss in a 2-mm wide stack coincided with the reduction in the engineering current density of the conductor, further reduction of ac loss was obtained through the splicing of the 2-mm wide tapes with low resistance solders

  12. Low ac loss geometries in YBCO coated conductors

    Energy Technology Data Exchange (ETDEWEB)

    Duckworth, R.C. [Oak Ridge National Laboratory, One Bethel Valley Road, P.O. Box 2008, MS-6305, Oak Ridge, TN 37831-6305 (United States)], E-mail: duckworthrc@ornl.gov; List, F.A.; Paranthaman, M.P. [Oak Ridge National Laboratory, One Bethel Valley Road, P.O. Box 2008, MS-6305, Oak Ridge, TN 37831-6305 (United States); Rupich, M.W.; Zhang, W. [American Superconductor, Two Technology Drive, Westborough, MA 01581 (United States); Xie, Y.Y.; Selvamanickam, V. [SuperPower, 450 Duane Ave, Schenectady, NY 12304 (United States)

    2007-10-01

    Reduction of ac losses in applied ac fields can be accomplished through either the creation of filaments and bridging in YBCO coated conductors or by an assembly of narrow width YBCO tapes. The ac losses for each of these geometries were measured at 77 K in perpendicular ac fields up to 100 mT. Despite physical isolation of the filaments, coupling losses were still present in the samples when compared to the expected hysteretic loss. In addition to filamentary conductors the assembly of stacked YBCO conductor provides an alternative method of ac loss reduction. When compared to a 4-mm wide YBCO coated conductor with a critical current of 60 A, the ac loss in a stack of 2-mm wide YBCO coated conductors with a similar total critical current was reduced. While the reduction in ac loss in a 2-mm wide stack coincided with the reduction in the engineering current density of the conductor, further reduction of ac loss was obtained through the splicing of the 2-mm wide tapes with low resistance solders.

  13. Drugs and hair loss.

    Science.gov (United States)

    Patel, Mansi; Harrison, Shannon; Sinclair, Rodney

    2013-01-01

    Hair loss is a common complaint, both in men and women, and use of prescription medications is widespread. When there is a temporal association between the onset of hair loss and commencement of a medication, the medication is commonly thought to have caused the hair loss. However, hair loss and in particular telogen effluvium may occur in response to a number of triggers including fever, hemorrhage, severe illness, stress, and childbirth, and a thorough exclusion of these potential confounders is necessary before the hair loss can be blamed on the medication. Certain medications are known to cause hair loss by a variety of mechanisms including anagen arrest, telogen effluvium, or accentuation of androgenetic alopecia by androgens. Crown Copyright © 2013. Published by Elsevier Inc. All rights reserved.

  14. Handbook on loss reserving

    CERN Document Server

    Schmidt, Klaus; Schnaus, Anja

    2016-01-01

    This handbook presents the basic aspects of actuarial loss reserving. Besides the traditional methods, it also includes a description of more recent ones and a discussion of certain problems occurring in actuarial practice, like inflation, scarce data, large claims, slow loss development, the use of market statistics, the need for simulation techniques and the task of calculating best estimates and ranges of future losses. In property and casualty insurance the provisions for payment obligations from losses that have occurred but have not yet been settled usually constitute the largest item on the liabilities side of an insurer's balance sheet. For this reason, the determination and evaluation of these loss reserves is of considerable economic importance for every property and casualty insurer. Actuarial students, academics as well as practicing actuaries will benefit from this overview of the most important actuarial methods of loss reserving by developing an understanding of the underlying stochastic models...

  15. Rain-induced spring wheat harvest losses

    Science.gov (United States)

    Bauer, A.; Black, A. L. (Principal Investigator)

    1983-01-01

    When rain or a combination of rain and high humidity delay wheat harvest, losses can occur in grain yield and/or grain quality. Yield losses can result from shattering, from reduction in test weight, and in the case of windrowed grain, from rooting of sprouting grain at the soil: windrow contact. Losses in grain quality can result from reduction in test weight and from sprouting. Sprouting causes a degradation of grain proteins and starches, hence flour quality is reduced, and the grain price deteriorates to the value of feed grain. Although losses in grain yield and quality are rain-induced, these losses do not necessarily occur because a standing or windrowed crop is wetted by rain. Spike water concentration in hard red spring wheat must be increased to about 45-49% before sprouting is initiated in grain that has overcome dormancy. The time required to overcome this dormancy after the cultivar has dried to 12 to 14% water concentration differs with hard red spring cultivars. The effect of rain on threshing-ready standing and windrowed hard red spring wheat grain yeild and quality was evaluated. A goal was to develop the capability to forecast the extent of expected loss of grain yield and quality from specific climatic events that delay threshing.

  16. Amygdala damage eliminates monetary loss aversion.

    Science.gov (United States)

    De Martino, Benedetto; Camerer, Colin F; Adolphs, Ralph

    2010-02-23

    Losses are a possibility in many risky decisions, and organisms have evolved mechanisms to evaluate and avoid them. Laboratory and field evidence suggests that people often avoid risks with losses even when they might earn a substantially larger gain, a behavioral preference termed "loss aversion." The cautionary brake on behavior known to rely on the amygdala is a plausible candidate mechanism for loss aversion, yet evidence for this idea has so far not been found. We studied two rare individuals with focal bilateral amygdala lesions using a series of experimental economics tasks. To measure individual sensitivity to financial losses we asked participants to play a variety of monetary gambles with possible gains and losses. Although both participants retained a normal ability to respond to changes in the gambles' expected value and risk, they showed a dramatic reduction in loss aversion compared to matched controls. The findings suggest that the amygdala plays a key role in generating loss aversion by inhibiting actions with potentially deleterious outcomes.

  17. FAA Perspective

    Science.gov (United States)

    Bond, Tom

    2009-01-01

    This viewgraph presentation describes the Federal Aviation Administration's perspective on improvements on aircraft icing. The most important areas that are discussed include: 1) Improvements in SLD engineering tools to meet concerns about means of compliance (MOC); and 2) 3-D iced aerodynamics.

  18. Comparative perspectives

    African Journals Online (AJOL)

    IT

    Ideology, policy and implementation: Comparative perspectives from two ... how both political as well as particular language ideologies play a major role in influencing and ..... attitudes as a field of research, many scholars still draw on the concept of .... The data for this study were collected through the use of questionnaires ...

  19. Digging Our Own Holes: Institutional Perspectives on Seismic Hazards

    Science.gov (United States)

    Stein, S.; Tomasello, J.

    2005-12-01

    life than normal commercial or residential buildings, and the direct and indirect losses resulting from their failure can be much larger. Hence the issue is balancing mitigating large losses in infrequent disasters with smaller but steady losses that may over time be greater. Finally, there has been little investigation of the benefits of mitigation regulations on the private sector relative to their consequences, which may significantly increase building costs, require seismic retrofits, and cause difficulties in securing loans and insurance. Possible outcomes include reduced economic activity (firms don't build or build elsewhere), job loss (or reduced growth), and the resulting reduction in tax revenue and thus public services. Given these complexities, organizations should be encouraged to examine broader societal issues beyond their institutional perspectives, and significant efforts should be made to develop a more integrated approach.

  20. Infinitary Combinatory Reduction Systems: Normalising Reduction Strategies

    NARCIS (Netherlands)

    Ketema, J.; Simonsen, Jakob Grue

    2010-01-01

    We study normalising reduction strategies for infinitary Combinatory Reduction Systems (iCRSs). We prove that all fair, outermost-fair, and needed-fair strategies are normalising for orthogonal, fully-extended iCRSs. These facts properly generalise a number of results on normalising strategies in

  1. Hereditary Hearing Loss.

    Science.gov (United States)

    Tran, LenhAnh P.; Grundfast, Kenneth M.

    1997-01-01

    This article discusses inheritance patterns in hearing loss, epidemiology, clues to genetic causes, locating genes that cause hereditary disorders, genes related to hearing loss disorders in individuals with Usher syndrome, Waardenburg syndrome, Treacher-Collins syndrome, Branchio-oto-renal and Pendred syndromes, and the significance of finding…

  2. Loss muinasjuturaamatust / Agu Veetamm

    Index Scriptorium Estoniae

    Veetamm, Agu, 1953-

    2004-01-01

    Ballindaloch on üks väheseid Shoti losse, kus omanikud aastaringselt elavad. 450 aastat on loss kuulunud Macpherson-Grantide suguvõsale. Praegu on lossi omanikuks Clare Nancy Macpherson-Grant Russell, kelle kujundatud on kiviktaimla ja rosaarium. Lossi ajaloost, omanikest, ümberehitustest, ringkäigust lossis, pargist. 14 ill

  3. Harm reduction-the cannabis paradox

    Directory of Open Access Journals (Sweden)

    Melamede Robert

    2005-09-01

    Full Text Available Abstract This article examines harm reduction from a novel perspective. Its central thesis is that harm reduction is not only a social concept, but also a biological one. More specifically, evolution does not make moral distinctions in the selection process, but utilizes a cannabis-based approach to harm reduction in order to promote survival of the fittest. Evidence will be provided from peer-reviewed scientific literature that supports the hypothesis that humans, and all animals, make and use internally produced cannabis-like products (endocannabinoids as part of the evolutionary harm reduction program. More specifically, endocannabinoids homeostatically regulate all body systems (cardiovascular, digestive, endocrine, excretory, immune, nervous, musculo-skeletal, reproductive. Therefore, the health of each individual is dependant on this system working appropriately.

  4. Concurrent credit portfolio losses.

    Science.gov (United States)

    Sicking, Joachim; Guhr, Thomas; Schäfer, Rudi

    2018-01-01

    We consider the problem of concurrent portfolio losses in two non-overlapping credit portfolios. In order to explore the full statistical dependence structure of such portfolio losses, we estimate their empirical pairwise copulas. Instead of a Gaussian dependence, we typically find a strong asymmetry in the copulas. Concurrent large portfolio losses are much more likely than small ones. Studying the dependences of these losses as a function of portfolio size, we moreover reveal that not only large portfolios of thousands of contracts, but also medium-sized and small ones with only a few dozens of contracts exhibit notable portfolio loss correlations. Anticipated idiosyncratic effects turn out to be negligible. These are troublesome insights not only for investors in structured fixed-income products, but particularly for the stability of the financial sector. JEL codes: C32, F34, G21, G32, H81.

  5. Reversible perspective and splitting in time.

    Science.gov (United States)

    Hart, Helen Schoenhals

    2012-01-01

    The element of time--the experience of it and the defensive use of it--is explored in conjunction with the use of reversible perspective as a psychotic defense. Clinical material from a long analysis illustrates how a psychotic patient used the reversible perspective, with its static splitting, to abolish the experience of time. When he improved and the reversible perspective became less effective for him, he replaced it with a more dynamic splitting mechanism using time gaps. With further improvement, the patient began to experience the passage of time, and along with it the excruciating pain of separation, envy, and loss.

  6. Reduction of Social Inequality in High School

    DEFF Research Database (Denmark)

    Jensen, Ulla Højmark

    2014-01-01

    This article explores structures in the learning environment at the classroom level that can contribute to reduction of social inequality in education. It draws on qualitative observation studies of Latino’s in high schools in New York City, USA, by a Danish researcher. The purpose of this article...... is to explore ‘good examples’ from an outsider’s perspective and there by create an empirical and theoretical focus on how school characteristics and structures cross boarders are connected to the reduction of social inequality in education....

  7. Heat losses in power boilers caused by thermal bridges

    Directory of Open Access Journals (Sweden)

    Kocot Monika

    2017-01-01

    Full Text Available In this article the analysis of heat losses caused by thermal bridges that occur in the steam boiler OP-140 is presented. Identification of these bridges were conducted with use of thermographic camera. Heat losses were evaluated based on methodology of VDI 4610 standard, but instead of its simplified equations, criterial equations based on Nusselt number were used. Obtained values of annual heat losses and heat flux density corresponding to the fully insulated boiler surfaces were compared to heat losses generated by thermal bridges located in the same areas. The emphasis is put on the role of industrial insulation in heat losses reduction.

  8. Structured building model reduction toward parallel simulation

    Energy Technology Data Exchange (ETDEWEB)

    Dobbs, Justin R. [Cornell University; Hencey, Brondon M. [Cornell University

    2013-08-26

    Building energy model reduction exchanges accuracy for improved simulation speed by reducing the number of dynamical equations. Parallel computing aims to improve simulation times without loss of accuracy but is poorly utilized by contemporary simulators and is inherently limited by inter-processor communication. This paper bridges these disparate techniques to implement efficient parallel building thermal simulation. We begin with a survey of three structured reduction approaches that compares their performance to a leading unstructured method. We then use structured model reduction to find thermal clusters in the building energy model and allocate processing resources. Experimental results demonstrate faster simulation and low error without any interprocessor communication.

  9. CO2 content of electricity losses

    International Nuclear Information System (INIS)

    Daví-Arderius, Daniel; Sanin, María-Eugenia; Trujillo-Baute, Elisa

    2017-01-01

    Countries are implementing policies to develop greener energy markets worldwide. In Europe, the ¨2030 Energy and Climate Package¨ asks for further reductions of green house gases, renewable sources integration, and energy efficiency targets. But the polluting intensity of electricity may be different in average than when considering market inefficiencies, in particular losses, and therefore the implemented policy must take those differences into account. Precisely, herein we study the importance in terms of CO2 emissions the extra amount of energy necessary to cover losses. With this purpose we use Spanish market and system data with hourly frequency from 2011 to 2013. Our results show that indeed electricity losses significantly explain CO2 emissions, with a higher CO2 emissions rate when covering losses than the average rate of the system. Additionally, we find that the market closing technologies used to cover losses have a positive and significant impact on CO2 emissions: when polluting technologies (coal or combined cycle) close the market, the impact of losses on CO2 emissions is high compared to the rest of technologies (combined heat and power, renewables or hydropower). To the light of these results we make some policy recommendations to reduce the impact of losses on CO2 emissions. - Highlights: • Electricity losses significantly explain CO2 emissions. • Policies aimed to reducing losses have a positive impact on CO2 emissions. • The market closing technology used to cover losses have impacts on CO2 emissions. • Pollutant technologies that close the market should be replaced by renewables.

  10. Aging Perspectives

    OpenAIRE

    Theodore D Cosco; David Brehme; Nora Grigoruta; Lisa-Katrin Kaufmann; Liis Lemsalu; Ruth Meex; Angela Schuurmans; Neslihan Sener

    2014-01-01

    Despite the proliferation of successful ageing (SA) research, the literature is dominated by researcher-driven Anglophone conceptualisations. To date, lay perspectives of SA have not been examined in Europe or Turkey. The current study aims to conduct a mixed-methods examination of conceptualisations of SA in seven underrepresented countries. Using snowball sampling via social media sites, an online survey consisting of established closed-ended and open-ended items – translated into seven lan...

  11. Some aspects of stray losses in large power transformers

    International Nuclear Information System (INIS)

    Valkovic, Zvonimir

    2002-01-01

    The paper presents some results of the investigation of stray losses in power transformers that are caused by high-current loops. The investigation was focused on: a) additional losses in tank cover around high-current bushings and the way of their reduction, b) extra leakage flux and additional losses due to high current delta-connections. The insertion of nonmagnetic gaps between the phase bushings reduces the extra cover losses more than three times. A nonmagnetic plate around the high-current bushings reduces these extra losses practically to zero. The extra losses due to the high-current delta-connections could be significant for the transformer loss level. These extra losses could be controlled (reduced) by the design layout of the delta-connections. (Author)

  12. Loss aversion in schizophrenia.

    Science.gov (United States)

    Trémeau, Fabien; Brady, Melissa; Saccente, Erica; Moreno, Alexis; Epstein, Henry; Citrome, Leslie; Malaspina, Dolores; Javitt, Daniel

    2008-08-01

    Loss aversion in decision-making refers to a higher sensitivity to losses than to gains. Loss aversion is conceived as an affective interference in cognitive processes such as judgment and decision-making. Loss aversion in non-risky choices has not been studied in schizophrenia. Forty-two individuals with schizophrenia and 42 non-patient control subjects, matched by gender and age, were randomized to two different scenarios (a buying scenario and a selling scenario). Subjects were asked to evaluate the price of a decorated mug. Schizophrenia subjects were re-tested four weeks later with the other scenario. Contrary to non-patient controls, schizophrenia subjects did not show loss aversion. In the schizophrenia group, absence of loss aversion was correlated with age, duration of illness, number of months in State hospitals, and poorer performance in the Wisconsin Card Sorting Test, but not with current psychopathology and two domains of emotional experience. Absence of loss aversion in schizophrenia represents a deficit in the processing of emotional information during decision-making. It can be interpreted as a lack of integration between the emotional and the cognitive systems, or to a more diffuse and de-differentiated impact of emotional information on decision-making. Future studies should bring more clarity to this question.

  13. Disaster risk reduction and sustainable development

    International Nuclear Information System (INIS)

    Khurshedi, N.

    2005-01-01

    During the past four decades, natural hazards such as earthquakes, volcanic activity, and slides, tsunami tropical cyclones and other severe storms, tornadoes and high winds, river floods and coastal flooding, wildfire and associated haze drought, sand/dust storms, and insect infestations have caused major loss of human lives and livelihoods, the destruction of economic and social infrastructure, as well as environmental damages. Economic losses have increased almost ten times during this period. As it happen in recent Asia Tsunami, in which over 2, 00,000 people reportedly killed, estimated five million homeless, and resulted in massive displacement of population and extensive damage to infrastructure. The escalation of severe disaster events triggered by natural hazards and related technological and environment disasters is increasingly threatening both sustainable development and poverty-reduction initiatives. The loss of human lives and the rise in the cost of reconstruction efforts and loss of development assets has forced the issue of disaster reduction and risk management higher on the policy agenda of affected governments as well a multilateral and bilateral agencies and NGOs. For this Disaster risk reduction-.strategies are aimed at enabling societies at risk to become engaged in the conscious management of risk and the reduction of vulnerability. The adoption of appropriate development policies can reduce disaster risk. These policies should be gender sensitive and need the necessary political commitment. They involve the adoption of suitable regulatory and other legal measures, institutional reform, improved analytical and methodological capabilities, financial planning, education and awareness. (author)

  14. Microbial minimalism: genome reduction in bacterial pathogens.

    Science.gov (United States)

    Moran, Nancy A

    2002-03-08

    When bacterial lineages make the transition from free-living or facultatively parasitic life cycles to permanent associations with hosts, they undergo a major loss of genes and DNA. Complete genome sequences are providing an understanding of how extreme genome reduction affects evolutionary directions and metabolic capabilities of obligate pathogens and symbionts.

  15. Nickel oxide reduction studied by environmental TEM

    DEFF Research Database (Denmark)

    Jeangros, Q.; Hansen, Thomas Willum; Wagner, Jakob Birkedal

    2012-01-01

    In situ reduction of an industrial NiO powder is performed under 1.3 mbar of H2 (2 mlN/min) in a differentially pumped FEI Titan 80-300 environmental transmission electron microscope (ETEM). Images, diffraction patterns and electron energy loss spectra (EELS) are acquired to monitor the structura...

  16. Reduction in language testing

    DEFF Research Database (Denmark)

    Dimova, Slobodanka; Jensen, Christian

    2013-01-01

    /video recorded speech samples and written reports produced by two experienced raters after testing. Our findings suggest that reduction or reduction-like pronunciation features are found in tested L2 speech, but whenever raters identify and comment on such reductions, they tend to assess reductions negatively......This study represents an initial exploration of raters' comments and actual realisations of form reductions in L2 test speech performances. Performances of three L2 speakers were selected as case studies and illustrations of how reductions are evaluated by the raters. The analysis is based on audio...

  17. Remifentanil Reduces Blood Loss During Orthognathic Surgery.

    Science.gov (United States)

    Matsuura, Nobuyuki; Okamura, Taiki; Ide, Satoko; Ichinohe, Tatsuya

    2017-01-01

    Remifentanil is reported to reduce oral tissue blood flow. We performed a retrospective investigation using logistic regression analysis of anesthesia records to investigate whether the use of remifentanil infusion in a balanced anesthesia technique was useful as a primary technique to reduce blood loss during orthognathic surgery. Subjects were 80 patients who underwent Le Fort I osteotomy and sagittal split ramus osteotomy of the mandible. The variables included gender, age, weight, type of maintenance anesthetic, type and dose or infusion rate of opioid, mean systolic blood pressure (SBP-mean), coefficient of variation of systolic blood pressure (CVSBP) during surgery, mean heart rate (HR-mean), duration of surgery, total blood loss, volume of infusion used, amount of local anesthetic used, body temperature, and urine output. Gender, type of maintenance anesthetic, type of opioid, SBP-mean, CVSBP, HR-mean, and duration of surgery were used as candidates for independent variables. Logistic regression analysis was performed for the selected independent variables with the total blood loss as the dependent variable. The factors associated with the reduction of blood loss were the use of remifentanil (odds ratio, 3.112; 95% CI, 1.166-8.307; P = .023) and smaller CVSBP (odds ratio, 2.747; 95% CI, 1.07-7.053; P = .036). Use of remifentanil and smaller CVSBP were associated with a reduction of blood loss during orthognathic surgery.

  18. School-based influenza vaccination: parents' perspectives.

    Directory of Open Access Journals (Sweden)

    Candace Lind

    Full Text Available School-age children are important drivers of annual influenza epidemics yet influenza vaccination coverage of this population is low despite universal publicly funded influenza vaccination in Alberta, Canada. Immunizing children at school may potentially increase vaccine uptake. As parents are a key stakeholder group for such a program, it is important to consider their concerns.We explored parents' perspectives on the acceptability of adding an annual influenza immunization to the immunization program that is currently delivered in Alberta schools, and obtained suggestions for structuring such a program.Forty-eight parents of children aged 5-18 years participated in 9 focus groups. Participants lived in urban areas of the Alberta Health Services Calgary Zone.Three major themes emerged: Advantages of school-based influenza vaccination (SBIV, Disadvantages of SBIV, and Implications for program design & delivery. Advantages were perceived to occur for different populations: children (e.g. emotional support, families (e.g. convenience, the community (e.g. benefits for school and multicultural communities, the health sector (e.g. reductions in costs due to burden of illness and to society at large (e.g. indirect conduit of information about health services, building structure for pandemic preparedness, building healthy lifestyles. Disadvantages, however, might also occur for children (e.g. older children less likely to be immunized, families (e.g. communication challenges, perceived loss of parental control over information, choices and decisions and the education sector (loss of instructional time. Nine second-level themes emerged within the major theme of Implications for program design & delivery: program goals/objectives, consent process, stakeholder consultation, age-appropriate program, education, communication, logistics, immunizing agent, and clinic process.Parents perceived advantages and disadvantages to delivering annual seasonal

  19. Beam Loss Monitors at LHC

    CERN Document Server

    Dehning, B.

    2016-01-01

    One of the main functions of the LHC beam loss measurement system is the protection of equipment against damage caused by impacting particles creating secondary showers and their energy dissipation in the matter. Reliability requirements are scaled according to the acceptable consequences and the frequency of particle impact events on equipment. Increasing reliability often leads to more complex systems. The downside of complexity is a reduction of availability; therefore, an optimum has to be found for these conflicting requirements. A detailed review of selected concepts and solutions for the LHC system will be given to show approaches used in various parts of the system from the sensors, signal processing, and software implementations to the requirements for operation and documentation.

  20. Signal Enhancement as Minimization of Relevant Information Loss

    OpenAIRE

    Geiger, Bernhard C.; Kubin, Gernot

    2012-01-01

    We introduce the notion of relevant information loss for the purpose of casting the signal enhancement problem in information-theoretic terms. We show that many algorithms from machine learning can be reformulated using relevant information loss, which allows their application to the aforementioned problem. As a particular example we analyze principle component analysis for dimensionality reduction, discuss its optimality, and show that the relevant information loss can indeed vanish if the r...

  1. The relationship between prevalence and duration of weight loss strategies and weight loss among overweight managed care organization members enrolled in a weight loss trial

    Directory of Open Access Journals (Sweden)

    Jeffery Robert W

    2006-02-01

    Full Text Available Abstract Background Many adults in the United States report engaging in weight loss behaviors. The current study examined weight loss strategies among managed care organization members, to determine the prevalence and impact of weight loss behaviors in this population. We hypothesized that greater engagement in weight loss strategies would be associated with greater weight loss success. Methods Data were taken from Weigh-to-Be (WTB, a two-year weight loss trial (N = 1801, 72% female, mean age = 50.7 years, mean weight = 95.9 kg, mean BMI = 34.2 kg/m2. Every six months, participants completed a questionnaire assessing frequency and duration of weight loss strategies (calorie reduction, fat reduction, increased fruit/vegetable intake, increased exercise, elimination of sweets, consumption of less food. General linear models and structural equation methods were used to examine associations between weight loss strategy use and weight change over time. Results Weight loss strategy prevalence rates ranged from 68% to 76% over two years. For all dietary strategies, any use of the strategy between baseline and 24 months was associated with weight loss at 24 months; those who did not engage in the strategy showed weight gains during that period. Results of general linear models and structural equation models indicated that increased use of weight loss strategies was significantly associated with greater 24-month weight loss. Conclusion The prevalence of weight loss strategies in this obese adult managed care population was quite high, and use of these strategies was associated in dose-response fashion with better weight loss. Future interventions may benefit from emphasis on persistence of similar strategies to achieve more successful outcomes.

  2. Panorama brasileiro do Programa de Boas Práticas de Laboratório. Impacto na redução do uso de animais | Brazilian Good Laboratory Practices Perspective. Impact on reduction in animal use

    Directory of Open Access Journals (Sweden)

    Elisa Rosa dos Santos

    2015-05-01

    in 1994. INMETRO initiated the GLP Program in 1995 for recognition and tracking on the basis of procedures, regulations, administrative and legal rules that establish guidelines, policies and directions to act with full responsibility and authority as the Brazilian monitoring authority to the principles of GLP. GLP studies are recognized by members and non-member countries with full membership to act according to the Organisation for Economic Co-operation and Development (OECD Mutual Acceptance of Data (MAD agreement and promote reduction in the number of animals used because of non-repetition of tests and adoption of validated alternative methods. In Brazil, there are 31 active GLP facilities, of which 5 perform in vivo tests. Normative Resolution 17/2014 of the National Council for the Control of Animal Experimentation establishes that animal tests that have validated alternative methods recognized by the Council will be replaced within 5 years with the expansion of BPL-based laboratories.

  3. Tailoring dietary approaches for weight loss.

    Science.gov (United States)

    Gardner, C D

    2012-07-01

    Although the 'Low-Fat' diet was the predominant public health recommendation for weight loss and weight control for the past several decades, the obesity epidemic continued to grow during this time period. An alternative 'low-carbohydrate' (Low-Carb) approach, although originally dismissed and even vilified, was comparatively tested in a series of studies over the past decade, and has been found in general to be as effective, if not more, as the Low-Fat approach for weight loss and for several related metabolic health measures. From a glass half full perspective, this suggests that there is more than one choice for a dietary approach to lose weight, and that Low-Fat and Low-Carb diets may be equally effective. From a glass half empty perspective, the average amount of weight lost on either of these two dietary approaches under the conditions studied, particularly when followed beyond 1 year, has been modest at best and negligible at worst, suggesting that the two approaches may be equally ineffective. One could resign themselves at this point to focusing on calories and energy intake restriction, regardless of macronutrient distributions. However, before throwing out the half-glass of water, it is worthwhile to consider that focusing on average results may mask important subgroup successes and failures. In all weight-loss studies, without exception, the range of individual differences in weight change within any particular diet groups is orders of magnitude greater than the average group differences between diet groups. Several studies have now reported that adults with greater insulin resistance are more successful with weight loss on a lower-carbohydrate diet compared with a lower-fat diet, whereas adults with greater insulin sensitivity are equally or more successful with weight loss on a lower-fat diet compared with a lower-carbohydrate diet. Other preliminary findings suggest that there may be some promise with matching individuals with certain genotypes to

  4. Medicines and Bone Loss

    Science.gov (United States)

    ... The doses of thyroid hormone used to treat hypothyroidism (underactive thyroid) don’t harm bone and shouldn’t be cause for concern. Only high doses, used for thyroid cancer treatment, can cause bone loss. High doses or long- ...

  5. Hearing loss - infants

    Science.gov (United States)

    ... can allow many infants to develop normal language skills without delay. In infants born with hearing loss, ... therapy allow many children to develop normal language skills at the same age as their peers with ...

  6. Hearing Loss: Screening Newborns

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Hearing Loss Screening Newborns Past Issues / Spring 2015 Table ... deafness, which account for most cases. Screening Newborns' Hearing Now Standard In 1993, children born in the ...

  7. Main sequence mass loss

    International Nuclear Information System (INIS)

    Brunish, W.M.; Guzik, J.A.; Willson, L.A.; Bowen, G.

    1987-01-01

    It has been hypothesized that variable stars may experience mass loss, driven, at least in part, by oscillations. The class of stars we are discussing here are the δ Scuti variables. These are variable stars with masses between about 1.2 and 2.25 M/sub θ/, lying on or very near the main sequence. According to this theory, high rotation rates enhance the rate of mass loss, so main sequence stars born in this mass range would have a range of mass loss rates, depending on their initial rotation velocity and the amplitude of the oscillations. The stars would evolve rapidly down the main sequence until (at about 1.25 M/sub θ/) a surface convection zone began to form. The presence of this convective region would slow the rotation, perhaps allowing magnetic braking to occur, and thus sharply reduce the mass loss rate. 7 refs

  8. Losses in variable fields

    International Nuclear Information System (INIS)

    Bronca, G.; Fevrier, A.; Genevey, P.; Perot, J.

    1974-01-01

    After a recall of the theory of losses in type 11 superconductors and review of recent work on this topic, the characteristics of what should be an ideal conductor for a pulsed magnet are given. The requirements of pulsed magnets for high energy physics are reviewed and total losses for a 1000 GeV synchrotron estimated. Finally, recent results of prototypes are reported along with the projects of superconducting synchrotron accelerators through the world. (author)

  9. Hair Loss Myths.

    Science.gov (United States)

    DiMarco, Gabriella; McMichael, Amy

    2017-07-01

    INTRODUCTION: Hair loss is a common complaint seen in dermatology clinics. From frustration and attempts at self-help, patients with hair loss may present to the dermatologist with false beliefs, or myths, about the causes of their condition and what treatments are effective. METHODS: We identified 12 common myths about hair loss, categorized as myths about minoxidil treatment, vitamin and mineral supplements, natural topical treatments, and hair care practices. We performed a PubMed search to find evidence to support or refute each myth. RESULTS: We found that there is little evidence to support many of these common hair loss myths. In some cases, randomized controlled trials have investigated the effects of particular therapies and point to the effectiveness of certain hair loss treatments. DISCUSSION: In many cases, there have not been sufficient randomized controlled trials to evaluate the effect of different therapies and hair care practices on hair loss. It is best to guide patients toward treatments with a long track record of efficacy and away from those where little is known scientifically. J Drugs Dermatol. 2017;16(7):690-694..

  10. Accent, Identity, and a Fear of Loss? ESL Students' Perspectives

    Science.gov (United States)

    McCrocklin, Shannon; Link, Stephanie

    2016-01-01

    Because many theorists propose a connection between accent and identity, some theorists have justifiably been concerned about the ethical ramifications of L2 pronunciation teaching. However, English-as-a-second-language (ESL) students often state a desire to sound like native speakers. With little research into ESL students' perceptions of links…

  11. Pathological gambling and the loss of willpower: a neurocognitive perspective.

    Science.gov (United States)

    Brevers, Damien; Noël, Xavier

    2013-01-01

    The purpose of this review is to gain more insight on the neurocognitive processes involved in the maintenance of pathological gambling. Firstly, we describe structural factors of gambling games that could promote the repetition of gambling experiences to such an extent that some individuals may become unable to control their gambling habits. Secondly, we review findings of neurocognitive studies on pathological gambling. As a whole, poor ability to resist gambling is a product of an imbalance between any one or a combination of three key neural systems: (1) an hyperactive 'impulsive' system, which is fast, automatic, and unconscious and promotes automatic and habitual actions; (2) a hypoactive 'reflective' system, which is slow and deliberative, forecasting the future consequences of a behavior, inhibitory control, and self-awareness; and (3) the interoceptive system, translating bottom-up somatic signals into a subjective state of craving, which in turn potentiates the activity of the impulsive system, and/or weakens or hijacks the goal-driven cognitive resources needed for the normal operation of the reflective system. Based on this theoretical background, we focus on certain clinical interventions that could reduce the risks of both gambling addiction and relapse.

  12. Pathological gambling and the loss of willpower: a neurocognitive perspective

    Directory of Open Access Journals (Sweden)

    Damien Brevers

    2013-09-01

    Full Text Available The purpose of this review is to gain more insight on the neurocognitive processes involved in the maintenance of pathological gambling. Firstly, we describe structural factors of gambling games that could promote the repetition of gambling experiences to such an extent that some individuals may become unable to control their gambling habits. Secondly, we review findings of neurocognitive studies on pathological gambling. As a whole, poor ability to resist gambling is a product of an imbalance between any one or a combination of three key neural systems: (1 an hyperactive ‘impulsive’ system, which is fast, automatic, and unconscious and promotes automatic and habitual actions; (2 a hypoactive ‘reflective’ system, which is slow and deliberative, forecasting the future consequences of a behavior, inhibitory control, and self-awareness; and (3 the interoceptive system, translating bottom-up somatic signals into a subjective state of craving, which in turn potentiates the activity of the impulsive system, and/or weakens or hijacks the goal-driven cognitive resources needed for the normal operation of the reflective system. Based on this theoretical background, we focus on certain clinical interventions that could reduce the risks of both gambling addiction and relapse.

  13. MCNP variance reduction overview

    International Nuclear Information System (INIS)

    Hendricks, J.S.; Booth, T.E.

    1985-01-01

    The MCNP code is rich in variance reduction features. Standard variance reduction methods found in most Monte Carlo codes are available as well as a number of methods unique to MCNP. We discuss the variance reduction features presently in MCNP as well as new ones under study for possible inclusion in future versions of the code

  14. Modern Reduction Methods

    CERN Document Server

    Andersson, Pher G

    2008-01-01

    With its comprehensive overview of modern reduction methods, this book features high quality contributions allowing readers to find reliable solutions quickly and easily. The monograph treats the reduction of carbonyles, alkenes, imines and alkynes, as well as reductive aminations and cross and heck couplings, before finishing off with sections on kinetic resolutions and hydrogenolysis. An indispensable lab companion for every chemist.

  15. Atmosphere Impact Losses

    Science.gov (United States)

    Schlichting, Hilke E.; Mukhopadhyay, Sujoy

    2018-02-01

    Determining the origin of volatiles on terrestrial planets and quantifying atmospheric loss during planet formation is crucial for understanding the history and evolution of planetary atmospheres. Using geochemical observations of noble gases and major volatiles we determine what the present day inventory of volatiles tells us about the sources, the accretion process and the early differentiation of the Earth. We further quantify the key volatile loss mechanisms and the atmospheric loss history during Earth's formation. Volatiles were accreted throughout the Earth's formation, but Earth's early accretion history was volatile poor. Although nebular Ne and possible H in the deep mantle might be a fingerprint of this early accretion, most of the mantle does not remember this signature implying that volatile loss occurred during accretion. Present day geochemistry of volatiles shows no evidence of hydrodynamic escape as the isotopic compositions of most volatiles are chondritic. This suggests that atmospheric loss generated by impacts played a major role during Earth's formation. While many of the volatiles have chondritic isotopic ratios, their relative abundances are certainly not chondritic again suggesting volatile loss tied to impacts. Geochemical evidence of atmospheric loss comes from the {}3He/{}^{22}Ne, halogen ratios (e.g., F/Cl) and low H/N ratios. In addition, the geochemical ratios indicate that most of the water could have been delivered prior to the Moon forming impact and that the Moon forming impact did not drive off the ocean. Given the importance of impacts in determining the volatile budget of the Earth we examine the contributions to atmospheric loss from both small and large impacts. We find that atmospheric mass loss due to impacts can be characterized into three different regimes: 1) Giant Impacts, that create a strong shock transversing the whole planet and that can lead to atmospheric loss globally. 2) Large enough impactors (m_{cap} ≳ √{2

  16. Primary culprit for tooth loss!!

    Directory of Open Access Journals (Sweden)

    Sailavanya Nuvvula

    2016-01-01

    Full Text Available Aim: In order to facilitate planning for dental health services and to progress strategies to continue the reduction in tooth loss, it is important to identify the factors that result in such loss. therefore the aim of the study is to investigate the major cause for tooth extraction. Objective: to examine whether the major reason for tooth extraction is dental caries or periodontal disease. Materials and Methods: The study is carried out among the dental practitioners in our district. A questionnaire containing 10 items was distributed to the dental practitioners, which included age, gender, no of teeth indicated for extraction, the reason for extraction, and the periodontal parameters that are involved with the extracted tooth and were requested to complete the form on every extraction they were to undertake. the study form was collected at the end of the study period and data was subjected to statistical analysis. Results: A total of 502 patients were enrolled during the study period, and a total of 1055 teeth were extracted for several reasons. we found that 51.14%extractions are due to dental caries in case of 20-30years age groups, which is more when compared to tooth loss due to periodontal diseases in this age group. whereas in case of >40years of age group periodontal diseases account for 54.11%, and dental caries accounts for only 29.11%. Showing more teeth were lost due to periodontal disease. Conclusion: therefore we concluded that, caries is the dominant reason for extraction in patients with 20–30 years of age while periodontal disease accounts for the majority of tooth extraction in patients older than 40 years.

  17. Tsunami Loss Assessment For Istanbul

    Science.gov (United States)

    Hancilar, Ufuk; Cakti, Eser; Zulfikar, Can; Demircioglu, Mine; Erdik, Mustafa

    2010-05-01

    Tsunami risk and loss assessment incorporating with the inundation mapping in Istanbul and the Marmara Sea region are presented in this study. The city of Istanbul is under the threat of earthquakes expected to originate from the Main Marmara branch of North Anatolian Fault System. In the Marmara region the earthquake hazard reached very high levels with 2% annual probability of occurrence of a magnitude 7+ earthquake on the Main Marmara Fault. Istanbul is the biggest city of Marmara region as well as of Turkey with its almost 12 million inhabitants. It is home to 40% of the industrial facilities in Turkey and operates as the financial and trade hub of the country. Past earthquakes have evidenced that the structural reliability of residential and industrial buildings, as well as that of lifelines including port and harbor structures in the country is questionable. These facts make the management of earthquake risks imperative for the reduction of physical and socio-economic losses. The level of expected tsunami hazard in Istanbul is low as compared to earthquake hazard. Yet the assets at risk along the shores of the city make a thorough assessment of tsunami risk imperative. Important residential and industrial centres exist along the shores of the Marmara Sea. Particularly along the northern and eastern shores we see an uninterrupted settlement pattern with industries, businesses, commercial centres and ports and harbours in between. Following the inundation maps resulting from deterministic and probabilistic tsunami hazard analyses, vulnerability and risk analyses are presented and the socio-economic losses are estimated. This study is part of EU-supported FP6 project ‘TRANSFER'.

  18. Weight reduction of automobile parts using light metals. Keikinzoku shiyo ni yoru jidosha buhin no keiryoka

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, S [Toyota Motor Corp., Aichi (Japan)

    1992-12-25

    Weight reduction of automobiles is required from the viewpoint of reduction of CO2 emission and energy conservation. Comparing a car with another one of almost the same size and performance with 1% reduced weight, combustion efficiency of the latter can be improved by 0.5-0.8%. This report introduces several examples, in which steel parts are replaced with light alloy parts to reduce car weight, and describes the future perspective. Concerning a cylinder block which is the heaviest part among engine parts, a block made of aluminum alloy with no cast liner has been developed. There is also an example of an oil pan adopting aluminum die-cast for a part of it. A valve lifter made of aluminum alloy has been developed for valve system parts and has contributed to friction loss, noise reduction, and improvement of fuel consumption. As for steering system parts, a steering bracket made of Mg alloy die-cast has been developed. The use of light alloy parts, in general, increases material cost. Therefore it is now required to build up closer connection between designs and production techniques and to improve reliability of casting and forging technologies. 5 refs., 20 figs.

  19. Religious architecture: anthropological perspectives

    NARCIS (Netherlands)

    Verkaaik, O.

    2013-01-01

    Religious Architecture: Anthropological Perspectives develops an anthropological perspective on modern religious architecture, including mosques, churches and synagogues. Borrowing from a range of theoretical perspectives on space-making and material religion, this volume looks at how religious

  20. Aging Perspectives

    Directory of Open Access Journals (Sweden)

    Theodore D Cosco

    2014-05-01

    Full Text Available Despite the proliferation of successful ageing (SA research, the literature is dominated by researcher-driven Anglophone conceptualisations. To date, lay perspectives of SA have not been examined in Europe or Turkey. The current study aims to conduct a mixed-methods examination of conceptualisations of SA in seven underrepresented countries. Using snowball sampling via social media sites, an online survey consisting of established closed-ended and open-ended items – translated into seven languages – was administered. Grounded theory methods and descriptive statistics were used to analyse qualitative and quantitative data, respectively.

  1. Loss, stress, and mental health.

    Science.gov (United States)

    Caplan, G

    1990-02-01

    1. The loss of an attachment to a loved person or of some other significant attachment leads to a prolonged period of distress and disability. 2. The upset feelings are usually associated with reduction in cognitive effectiveness and problem-solving capacity, the magnitude of which is dependent on the intensity and duration of emotional arousal. There is a reduced capacity for collecting and processing information and for access to relevant memories that associate significant meaning to perceptions. There is also a deterioration in the clarity of the person's self-concept and in his capacity to assess his ability to persevere in the face of discomfort, which weakens his will to struggle. 3. The disability following loss of an attachment is the product of three interlocking factors: (a) the pain of the rupture in the bond and the agony of coming to terms with this reality, (b) the handicapping privation of the missing assets previously derived from the lost person or resource, and (c) the cognitive erosion and reduction in problem-solving capacities and of the will to persevere. 4. These factors may lead to poor mental health in the form of an acute adjustment disorder, or else of chronic psychopathology if the individual uses maladaptive ways of trying to escape his burdens through alienation from reality or through the irrational mechanisms of psychoneurotic symptoms, or if prolonged emotional tension leads to malfunctioning of a bodily system. On the other hand, if the individual masters his problems by working out ways of effective coping, he may emerge from the experience with increased competence and resilience. 5. Eventual mastery of the burdensome experience involves reorganization of the individual's "assumptive world," namely of his intrapsychic maps of external reality and his internal system for guiding and motivating his behavior, which have been disorganized by the loss of their anchorage in the ruptured attachment. 6. This reorganization is helped by

  2. MANAGEMENT OF CREDIT LOSSES

    Directory of Open Access Journals (Sweden)

    Natalya P. Anoshkina

    2018-06-01

    Full Text Available The paper is devoted to the problem of credit loss management topical for modern Russian science and banking practice. The bank’s lending activity is an integral and the most profitable sphere of banking activity. Banks need to take credit risks inherent in their core business and minimize their impact through the establishment of advanced risk management systems. The study, reflected in the present paper, has been conducted in order to determine approaches to the organization of credit loss management in banking. Analysis of the system of management of credit risks and credit losses has shown that they have different scope, object and purpose. In this connection, there is an objective necessity to create a special subsystem for the management of credit losses in banks. On the basis of common bank approaches to credit risk management, the paper develops models of credit loss management: a multi-level management model in the area of ‘operational-tactical-strategic management’ and a functional management model in the area of ‘technology-execution-control’. These models are important for the modern theory and practice of banking, as they allow the bank to manage credit losses on the entire time horizon of the management process, thus opening a wide range of opportunities for the creation and implementation of large-scale programs, as well as specific techniques. This study allows drawing a conclusion about the need to consider control credit losses as a strictly regulated multi-level process, in which each division is assigned with specific objectives, tasks, functions, formally enshrined in the relevant lists, job descriptions and other legal documents.

  3. Elementary Music Teachers' Perceptions of the Effect of Budget Reductions on Music Education

    Science.gov (United States)

    Michel, Jimmy

    2018-01-01

    Since 2007, many U.S. music education programs have been negatively affected by budget reductions at the local, state, and national levels. Although researchers have studied the effect of budget reductions on music education, they have not widely examined the perspectives of teachers who have experienced these reductions. The purpose of this study…

  4. Early Sport Specialization: A Psychological Perspective

    Science.gov (United States)

    Gould, Daniel

    2010-01-01

    Specializing too early in life can lead to emotional stress, loss of motivation, and burnout, but the research is inadequate to resolve the question of whether early specialization or diversification is more beneficial from a psychological perspective. Nevertheless, some best practices are recommended based on the known benefits and detriments.…

  5. MENTAL HEALTH: ISLAMIC PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Muzdalifah M. Rahman

    2015-02-01

    of mental health, especially mental health needs to be developed with an Islamic perspective various studies and research, especially the development of mental health recovery means Islamic perspective.

  6. Global warming: is weight loss a solution?

    Science.gov (United States)

    Gryka, A; Broom, J; Rolland, C

    2012-03-01

    The current climate change has been most likely caused by the increased greenhouse gas emissions. We have looked at the major greenhouse gas, carbon dioxide (CO(2)), and estimated the reduction in the CO(2) emissions that would occur with the theoretical global weight loss. The calculations were based on our previous weight loss study, investigating the effects of a low-carbohydrate diet on body weight, body composition and resting metabolic rate of obese volunteers with type 2 diabetes. At 6 months, we observed decreases in weight, fat mass, fat free mass and CO(2) production. We estimated that a 10 kg weight loss of all obese and overweight people would result in a decrease of 49.560 Mt of CO(2) per year, which would equal to 0.2% of the CO(2) emitted globally in 2007. This reduction could help meet the CO(2) emission reduction targets and unquestionably would be of a great benefit to the global health.

  7. Thinking like a trader selectively reduces individuals' loss aversion.

    Science.gov (United States)

    Sokol-Hessner, Peter; Hsu, Ming; Curley, Nina G; Delgado, Mauricio R; Camerer, Colin F; Phelps, Elizabeth A

    2009-03-31

    Research on emotion regulation has focused upon observers' ability to regulate their emotional reaction to stimuli such as affective pictures, but many other aspects of our affective experience are also potentially amenable to intentional cognitive regulation. In the domain of decision-making, recent work has demonstrated a role for emotions in choice, although such work has generally remained agnostic about the specific role of emotion. Combining psychologically-derived cognitive strategies, physiological measurements of arousal, and an economic model of behavior, this study examined changes in choices (specifically, loss aversion) and physiological correlates of behavior as the result of an intentional cognitive regulation strategy. Participants were on average more aroused per dollar to losses relative to gains, as measured with skin conductance response, and the difference in arousal to losses versus gains correlated with behavioral loss aversion across subjects. These results suggest a specific role for arousal responses in loss aversion. Most importantly, the intentional cognitive regulation strategy, which emphasized "perspective-taking," uniquely reduced both behavioral loss aversion and arousal to losses relative to gains, largely by influencing arousal to losses. Our results confirm previous research demonstrating loss aversion while providing new evidence characterizing individual differences and arousal correlates and illustrating the effectiveness of intentional regulation strategies in reducing loss aversion both behaviorally and physiologically.

  8. Congenital sensorineural hearing loss

    International Nuclear Information System (INIS)

    Mafee, M.F.; Selis, J.E.; Yannias, D.A.; Valvassori, G.E.; Pruzansky, S.; Applebaum, E.L.; Capek, V.

    1984-01-01

    The ears of 47 selected patients with congenital sensorineural hearing loss were examined with complex-motion tomography. The patients were divided into 3 general categories: those with a recognized syndrome, those with sensorineural hearing loss unrelated to any known syndrome, and those with microtia. A great variety of inner ear anomalies was detected, but rarely were these characteristic of a particular clinical entity. The most common finding was the Mondini malformation or one of its variants. Isolated dysplasia of the internal auditory canal or the vestibular aqueduct may be responsible for sensorineural hearing loss in some patients. Patients with microtia may also have severe inner ear abnormalities despite the fact that the outer and inner ears develop embryologically from completely separate systems

  9. Congenital sensorineural hearing loss

    Energy Technology Data Exchange (ETDEWEB)

    Mafee, M.F.; Selis, J.E.; Yannias, D.A.; Valvassori, G.E.; Pruzansky, S.; Applebaum, E.L.; Capek, V.

    1984-02-01

    The ears of 47 selected patients with congenital sensorineural hearing loss were examined with complex-motion tomography. The patients were divided into 3 general categories: those with a recognized syndrome, those with sensorineural hearing loss unrelated to any known syndrome, and those with microtia. A great variety of inner ear anomalies was detected, but rarely were these characteristic of a particular clinical entity. The most common finding was the Mondini malformation or one of its variants. Isolated dysplasia of the internal auditory canal or the vestibular aqueduct may be responsible for sensorineural hearing loss in some patients. Patients with microtia may also have severe inner ear abnormalities despite the fact that the outer and inner ears develop embryologically from completely separate systems.

  10. Computer loss experience and predictions

    Science.gov (United States)

    Parker, Donn B.

    1996-03-01

    The types of losses organizations must anticipate have become more difficult to predict because of the eclectic nature of computers and the data communications and the decrease in news media reporting of computer-related losses as they become commonplace. Total business crime is conjectured to be decreasing in frequency and increasing in loss per case as a result of increasing computer use. Computer crimes are probably increasing, however, as their share of the decreasing business crime rate grows. Ultimately all business crime will involve computers in some way, and we could see a decline of both together. The important information security measures in high-loss business crime generally concern controls over authorized people engaged in unauthorized activities. Such controls include authentication of users, analysis of detailed audit records, unannounced audits, segregation of development and production systems and duties, shielding the viewing of screens, and security awareness and motivation controls in high-value transaction areas. Computer crimes that involve highly publicized intriguing computer misuse methods, such as privacy violations, radio frequency emanations eavesdropping, and computer viruses, have been reported in waves that periodically have saturated the news media during the past 20 years. We must be able to anticipate such highly publicized crimes and reduce the impact and embarrassment they cause. On the basis of our most recent experience, I propose nine new types of computer crime to be aware of: computer larceny (theft and burglary of small computers), automated hacking (use of computer programs to intrude), electronic data interchange fraud (business transaction fraud), Trojan bomb extortion and sabotage (code security inserted into others' systems that can be triggered to cause damage), LANarchy (unknown equipment in use), desktop forgery (computerized forgery and counterfeiting of documents), information anarchy (indiscriminate use of

  11. Weight Loss Nutritional Supplements

    Science.gov (United States)

    Eckerson, Joan M.

    Obesity has reached what may be considered epidemic proportions in the United States, not only for adults but for children. Because of the medical implications and health care costs associated with obesity, as well as the negative social and psychological impacts, many individuals turn to nonprescription nutritional weight loss supplements hoping for a quick fix, and the weight loss industry has responded by offering a variety of products that generates billions of dollars each year in sales. Most nutritional weight loss supplements are purported to work by increasing energy expenditure, modulating carbohydrate or fat metabolism, increasing satiety, inducing diuresis, or blocking fat absorption. To review the literally hundreds of nutritional weight loss supplements available on the market today is well beyond the scope of this chapter. Therefore, several of the most commonly used supplements were selected for critical review, and practical recommendations are provided based on the findings of well controlled, randomized clinical trials that examined their efficacy. In most cases, the nutritional supplements reviewed either elicited no meaningful effect or resulted in changes in body weight and composition that are similar to what occurs through a restricted diet and exercise program. Although there is some evidence to suggest that herbal forms of ephedrine, such as ma huang, combined with caffeine or caffeine and aspirin (i.e., ECA stack) is effective for inducing moderate weight loss in overweight adults, because of the recent ban on ephedra manufacturers must now use ephedra-free ingredients, such as bitter orange, which do not appear to be as effective. The dietary fiber, glucomannan, also appears to hold some promise as a possible treatment for weight loss, but other related forms of dietary fiber, including guar gum and psyllium, are ineffective.

  12. Microgrids: Energy management by loss minimization technique

    Energy Technology Data Exchange (ETDEWEB)

    Basu, A.K. [Electrical Engineering Dept., Jadavpur University & 20/2, Khanpur Road, Kolkata 700047 (India); Chowdhury, S.; Chowdhury, S.P. [Electrical Engineering Department, University of Cape Town & Private Bag X3, Menzies Building, Room-517, Rondebosch, Cape Town 7701 (India)

    2011-07-01

    Energy management is a techno-economic issue, which dictates, in the context of microgrids, how optimal investment in technology front could bring optimal power quality and reliability (PQR) of supply to the consumers. Investment in distributed energy resources (DERs), with their connection to the utility grid at optimal locations and with optimal sizes, saves energy in the form of line loss reduction. Line loss reduction is the indirect benefit to the microgrid owner who may recover it as an incentive from utility. The present paper focuses on planning of optimal siting and sizing of DERs based on minimization of line loss. Optimal siting is done, here, on the loss sensitivity index (LSI) method and optimal sizing by differential evolution (DE) algorithms, which is, again, compared with particle swarm optimization (PSO) technique. Studies are conducted on 6-bus and 14-bus radial networks under islanded mode of operation with electric demand profile. Islanding helps planning of DER capacity of microgrid, which is self-sufficient to cater its own consumers without utility's support.

  13. Mental stress as consequence and cause of vision loss: the dawn of psychosomatic ophthalmology for preventive and personalized medicine.

    Science.gov (United States)

    Sabel, Bernhard A; Wang, Jiaqi; Cárdenas-Morales, Lizbeth; Faiq, Muneeb; Heim, Christine

    2018-06-01

    The loss of vision after damage to the retina, optic nerve, or brain has often grave consequences in everyday life such as problems with recognizing faces, reading, or mobility. Because vision loss is considered to be irreversible and often progressive, patients experience continuous mental stress due to worries, anxiety, or fear with secondary consequences such as depression and social isolation. While prolonged mental stress is clearly a consequence of vision loss, it may also aggravate the situation. In fact, continuous stress and elevated cortisol levels negatively impact the eye and brain due to autonomous nervous system (sympathetic) imbalance and vascular dysregulation; hence stress may also be one of the major causes of visual system diseases such as glaucoma and optic neuropathy. Although stress is a known risk factor, its causal role in the development or progression of certain visual system disorders is not widely appreciated. This review of the literature discusses the relationship of stress and ophthalmological diseases. We conclude that stress is both consequence and cause of vision loss. This creates a vicious cycle of a downward spiral, in which initial vision loss creates stress which further accelerates vision loss, creating even more stress and so forth. This new psychosomatic perspective has several implications for clinical practice. Firstly, stress reduction and relaxation techniques (e.g., meditation, autogenic training, stress management training, and psychotherapy to learn to cope) should be recommended not only as complementary to traditional treatments of vision loss but possibly as preventive means to reduce progression of vision loss. Secondly, doctors should try their best to inculcate positivity and optimism in their patients while giving them the information the patients are entitled to, especially regarding the important value of stress reduction. In this way, the vicious cycle could be interrupted. More clinical studies are now

  14. ECT and memory loss.

    Science.gov (United States)

    Squire, L R

    1977-09-01

    The author reviews several studies that clarify the nature of the memory loss associated with ECT. Bilateral ECT produced greater anterograde memory loss than right unilateral ECT and more extensive retrograde amnesia than unilateral ECT. Reactivating memories just before ECT did not produce amnesia. Capacity for new learning recovered substantially by several months after ECT, but memory complaints were common in individuals who had received bilateral ECT. Other things being equal, right unilateral ECT seems preferable to bilateral ECT because the risks to memory associated with unilateral ECT are smaller.

  15. Recurrent Pregnancy Loss

    Directory of Open Access Journals (Sweden)

    Véronique Piroux

    1997-01-01

    Full Text Available Antiphospholipid antibodies (APA are associated with thrombosis, thrombocytopenia and fetal loss but they occur in a variety of diseases. Despite many efforts, a correlation between the specificity of particular subgroups of APA and particular clinical situations remains to be established. The antigens at the origin of APA remain to be identified. We discuss here the possible links between cell apoptosis or necrosis, leading to plasma membrane alterations, and the occurrence of APA in response to sustained stimulation. The pathogenic potential of APA is also considered with respect to recurrent pregnancy loss.

  16. Loss of chance in medical negligence.

    Science.gov (United States)

    Leslie, K; Bramley, D; Shulman, M; Kennedy, E

    2014-05-01

    Occasionally accidents and complications occur during anaesthesia and perioperative care that result in injury to the patient. Unfortunately, this is sometimes due to a breach in the anaesthetist's duty of care to the patient. Sometimes, rather than being the cause of immediate damage, the act or omission results in an alteration in the prognosis of the complaint or increased risk of complications related to the complaint. This avenue for a negligence action is known as 'loss of chance of a better outcome' and has been the subject of much legal argument in Australia in recent years. A recent High Court of Australia decision is widely seen as having 'closed the door' to, or at least made it difficult for the patient to succeed in, loss of chance cases. Many anaesthetists may not be familiar with the concept of 'loss of chance'. This review will explore the concept of loss of chance and the manner in which Australian courts have dealt with it before and after Tabet v Gett from the perspective of the anaesthetist.

  17. Causes of visual loss in uveitis

    Directory of Open Access Journals (Sweden)

    Stanković Zora

    2009-01-01

    Full Text Available Background/Aim. Epidemiological studies of blindness in a working age population require a precise definition of the true connection of uveitis and visual damage. Since most patients with more severe types of uveitis are hospitalized in tertiary referral uveitis service, our aim was to determine whether age, sex and age of onset of uveitis, as well as duration of visual loss and its causes influence the degree of visual damage in patients with different types of uveitis. Methods. The data were collected from medical records of 237 patients at the Department for Uveitis of the Institute for Eye Diseases in Belgrade over a three-year period (March 2005 to March 2008. Results. Visual acuity reduction (≤ 0.3 was found in 161/237 (67.9% patients, 85 of whom had visual acuity of ≤ 0.1 later. Working age patients (up to 60 years of age most often suffered from uveitis (173/237; 73%. The highest number of patients with visual loss was in the group suffering from panuveitis (77/94; 81.91%. The age of onset of uveitis and sex have no statistically significant influence on visual loss. The most common causes of visual loss (34/161; 21.1% were cystoid macular oedema (CMO (43/161; 26.7%, cataract (28/161; 17.39% and combination of CMO and cataract. Conclusion. The risk factors for severe visual loss (≤ 0.1 are panuveitis, bilateral inflammation, prolonged visual reduction and a significant number of relapses. The main causes of visual loss in 65.2% of our patients were CMO and cataract.

  18. Side Effects: Hair Loss (Alopecia)

    Science.gov (United States)

    Hair loss, also called alopecia, is a side effect of cancer treatments, such as chemotherapy and radiation therapy. Learn how to cope with and manage hair loss. Listen to tips from others who have experienced hair loss.

  19. Energy losses of superconducting power transmission cables in the grid

    DEFF Research Database (Denmark)

    Østergaard, Jacob; Okholm, Jan; Lomholt, Karin

    2001-01-01

    One of the obvious motives for development of superconducting power transmission cables is reduction of transmission losses. Loss components in superconducting cables as well as in conventional cables have been examined. These losses are used for calculating the total energy losses of conventional...... as well as superconducting cables when they are placed in the electric power transmission network. It is concluded that high load connections are necessary to obtain energy saving by the use of HTSC cables. For selected high load connections, an energy saving of 40% is expected. It is shown...

  20. Reduction - competitive tomorrow

    International Nuclear Information System (INIS)

    Worley, L.; Bargerstock, S.

    1995-01-01

    Inventory reduction is one of the few initiatives that represent significant cost-reduction potential that does not result in personnel reduction. Centerior Energy's Perry nuclear power plant has embarked on an aggressive program to reduce inventory while maintaining plant material availability. Material availability to the plant was above 98%, but at an unacceptable 1994 inventory book value of $47 million with inventory carrying costs calculated at 30% annually

  1. Optimal Phase Balancing Planning for Loss Reduction in Distribution Systems using a Specialized Genetic Algorithm Planeamiento Optimo de Balance de Fases para Reducción de Perdidas en Sistemas de Distribución usando un Algoritmo Genético Especializado

    Directory of Open Access Journals (Sweden)

    Mauricio Granada Echeverri

    2012-06-01

    Full Text Available Unbalanced operation of distribution systems deteriorates power quality andincreases investment and operation costs. Feeder reconfiguration and phaseswapping are the two main approaches for load balancing, being the formermore difficult to execute due to the reduced number of sectionalizing switchesavailable in most distribution systems. On the other hand, phase swappingconstitutes a direct, effective and low cost alternative for load balancing. The main contribution of this paper is the proposal of an optimization model anda solution technique for phase balancing planning in distribution systems. Asregards the optimization model, a mixed integer nonlinear programming formulationis proposed. On the other hand, the proposed solution techniqueconsists on a specialized genetic algorithm. To show the effectiveness of theproposed approach, several tests are carried out with two distribution systemsof 37 and 19 buses, this last one with different load models. Results showedthat in addition to the achievement of the primary objective of loss reduction,phase balancing allows obtaining other technical benefits such as improvementof voltage profile and alleviation of congested lines.La operación desbalanceada de los sistemas de distribución deteriora la calidad de la potencia y aumenta los costos de inversión y operación. La reconfiguración de alimentadores y el intercambio de fases son los dos principales enfoques para balance de fases, siendo el primero más difícil de llevar a cabo debido al número reducido de seccionalizadores disponibles en la mayoría de los sistemas de distribución. Por otro lado, el intercambio de fases constituye una alternativa directa, efectiva y de bajo costo para el balance de fases. La contribución principal de este artículo es la propuesta de un modelo de optimización y una técnica de solución para el planeamiento de balance de fases en sistemas de distribución. En cuanto al modelo de optimización, se

  2. Future perspectives

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    International involvement in particle physics is what the International Committee for Future Accelerators (ICFA) is all about. At the latest Future Perspectives meeting at Brookhaven from 5-10 October (after a keynote speech by doyen Viktor Weisskopf, who regretted the emergence of 'a nationalistic trend'), ICFA reviewed progress and examined its commitments in the light of the evolving world particle physics scene. Particular aims were to review worldwide accelerator achievements and plans, to survey the work of the four panels, and to discuss ICFA's special role in future cooperation in accelerator construction and use, and in research and development work for both accelerators and for detectors

  3. Cosmic Perspectives

    Science.gov (United States)

    Biswas, S. K.; Mallik, D. C. V.; Vishveshwara, C. V.

    2008-07-01

    1. Astronomy in ancient and medieval China Joseph Needham; 2. Indian astronomy: an historical perspective B. V. Subbarayappa; 3. Making of astronomy in ancient India Debiprasad Chattopadhyaya; 4. The impact of astronomy on the development of western science Jean-Claude Pecker; 5. Man and the Universe Hubert Reeves; 6. Understanding the Universe - challenges and directions in modern observational astronomy Harlan Smith, Jr: 7. Frontiers in cosmology Fred Hoyle; 8. Did the Universe originate in a big bang? Jayant Narlikar; 9. The dark matter problem Bernard Carr; 10. Geometry and the Universe C. V. Vishveshwara; 11. The origin and evolution of life Cyril Ponnamperuma; 12. The anthropic principle: self selection as an adjunct to natural selection Brandon Carter; 13. Astrology and science: an examination of the evidence Ivan Kelly, Roger Culver and Peter Loptson; 14. Astronomy and science fiction Allen Janis.

  4. Inverse perspective

    Science.gov (United States)

    Dolinsky, Margaret

    2006-02-01

    This paper will discuss the potentiality towards a methodology for creating perceptual shifts in virtual reality (VR) environments. A perceptual shift is a cognitive recognition of having experienced something extra-marginal, on the boundaries of normal awareness, outside of conditioned attenuation. Definitions of perceptual shifts demonstrate a historical tradition for the wonder of devices as well as analyze various categories of sensory and optical illusions. Neuroscience and cognitive science attempt to explain perceptual shifts through biological and perceptual mechanisms using the sciences. This paper explores perspective, illusion and projections to situate an artistic process in terms of perceptual shifts. Most VR environments rely on a single perceptual shift while there remains enormous potential for perceptual shifts in VR. Examples of artwork and VR environments develop and present this idea.

  5. Ionization loss in BGO

    International Nuclear Information System (INIS)

    Bakken, J.A.; Denes, P.; Piroue, P.A.; Stickland, D.P.; Sumner, R.L.; Taylor, C.; Barone, L.; Borgia, B.; Diemoz, M.; Dionisi, C.; Falciano, S.; Ferroni, F.; Gratta, G.; Longo, E.; Luminari, L.; Morganti, S.; Valente, E.; Blaising, J.J.; Boutigny, D.; Coignet, G.; Karyotakis, Y.; Sauvage, G.; Schneegans, M.; Vivargent, M.; Extermann, P.; Morand, G.; Ossmann, J.; Ruckstuhl, W.; Schaad, T.P.; Lecoq, P.; Walk, W.; Li, P.J.; Micke, M.; Micke, U.; Schmitz, D.

    1988-01-01

    We report on a precise measurement of the energy loss through ionization by pions in bismuth germanate performed at several values of the incident particles momentum with a prototype of the L3 electromagnetic calorimeter. The experimental results are in good agreement with theoretical predictions showing the relativistic rise modified by density effect. (orig.)

  6. Heat loss from Buildings

    DEFF Research Database (Denmark)

    Karlsson, Kenneth; Næraa, Rikke

    1997-01-01

    Determination of heat loss coefficients for buildings in Denmark. The coefficient are determined for 15 building groups and 3 year intervals. They are based on the BBR-registre and assumptions of U-values(W/K*m2)and computed in a simple spreed sheet model.The results are used in the REVEILLE...

  7. Independents' group posts loss

    International Nuclear Information System (INIS)

    Sanders, V.; Price, R.B.

    1992-01-01

    Low oil gas prices and special charges caused the group of 50 U.S. independent producers Oil and Gas Journal tracks to post a combined loss in first half 1992. The group logged a net loss of $53 million in the first half compared with net earnings of $354 million in first half 1991, when higher oil prices during the Persian Gulf crisis buoyed earnings in spite of crude oil and natural gas production declines. The combined loss in the first half follows a 45% drop in the group's earnings in 1991 and compares with the OGJ group of integrated oil companies whose first half 1992 income fell 47% from the prior year. Special charges, generally related to asset writedowns, accounted for most of the almost $560 million in losses posted by about the third of the group. Nerco Oil and Gas Inc., Vancouver, Wash., alone accounted for almost half that total with charges related to an asset writedown of $238 million in the first quarter. Despite the poor first half performance, the outlook is bright for sharply improved group earnings in the second half, assuming reasonably healthy oil and gas prices and increased production resulting from acquisitions and in response to those prices

  8. Deafness and Hearing Loss.

    Science.gov (United States)

    National Information Center for Children and Youth with Disabilities, Washington, DC.

    This brief overview provides information on the definition, incidence, and characteristics of children with hearing impairments and deafness. The federal definitions of hearing impairment and deafness are provided. The different types of hearing loss are noted, including: (1) conductive (caused by diseases or obstructions in the outer or middle…

  9. Pregnancy Loss and Miscarriage

    Science.gov (United States)

    ... Bulletins-Gynecology/Early-Pregnancy-Loss What are common symptoms? Causes and Risks How is it diagnosed? Is there a way to prevent? Related A-Z Topics High-Risk Pregnancy Polycystic Ovary Syndrome (PCOS) Stillbirth NICHD News Spotlights Release: Anti-HIV ...

  10. Process energy reduction

    International Nuclear Information System (INIS)

    Lowthian, W.E.

    1993-01-01

    Process Energy Reduction (PER) is a demand-side energy reduction approach which complements and often supplants other traditional energy reduction methods such as conservation and heat recovery. Because the application of PER is less obvious than the traditional methods, it takes some time to learn the steps as well as practice to become proficient in its use. However, the benefit is significant, often far outweighing the traditional energy reduction approaches. Furthermore, the method usually results in a better process having less waste and pollution along with improved yields, increased capacity, and lower operating costs

  11. Finding optimal exact reducts

    KAUST Repository

    AbouEisha, Hassan M.

    2014-01-01

    The problem of attribute reduction is an important problem related to feature selection and knowledge discovery. The problem of finding reducts with minimum cardinality is NP-hard. This paper suggests a new algorithm for finding exact reducts with minimum cardinality. This algorithm transforms the initial table to a decision table of a special kind, apply a set of simplification steps to this table, and use a dynamic programming algorithm to finish the construction of an optimal reduct. I present results of computer experiments for a collection of decision tables from UCIML Repository. For many of the experimented tables, the simplification steps solved the problem.

  12. Metallothermic reduction of molybdate

    International Nuclear Information System (INIS)

    Mukherjee, T.K.; Bose, D.K.

    1987-01-01

    This paper gives a brief account of the investigations conducted so far on metallothermic reduction of high grade molybdenite with particular emphasis on the work carried out in Bhabha Atomic Research Centre. Based on thermochemical considerations, the paper first introduces a number of metallic reductants suitable for use in metallothermic reduction of molybdenite. Aluminium, sodium and tin are found to be suitable reducing agents and very rightly they have found most applications in the research and development efforts on metallothermic reduction of molybdenite. The reduction with tin was conducted on fairly large scale both in vacuum and hydrogen atmosphere. The reaction was reported to be invariant depending mainly on the reduction temperature and a temperature of the order of 1250deg to 1300degC was required for good metal recovery. In comparison to tin, aluminothermic reduction of molybdenite was studied more extensively and it was conducted in closed bomb, vacuum and also in open atmosphere. In aluminothermic reduction, the influence of amount of reducing agent, amount of heat booster, preheating temperature and charging procedure on these metal yield was studied in detail. The reduction generally yielded massive molybdenum metal contaminated with aluminium as the major impurity element. Efforts were made to purify the reduced metal by arc melting, electron beam melting and molten salt electrorefining. 9 refs. (author)

  13. Simultaneous bilateral laser therapy accelerates recovery after noise-induced hearing loss in a rat model

    Directory of Open Access Journals (Sweden)

    Jae-Hun Lee

    2016-07-01

    Full Text Available Noise-induced hearing loss is a common type of hearing loss. The effects of laser therapy have been investigated from various perspectives, including in wound healing, inflammation reduction, and nerve regeneration, as well as in hearing research. A promising feature of the laser is its capability to penetrate soft tissue; depending on the wavelength, laser energy can penetrate into the deepest part of the body without damaging non-target soft tissues. Based on this idea, we developed bilateral transtympanic laser therapy, which uses simultaneous laser irradiation in both ears, and evaluated the effects of bilateral laser therapy on cochlear damage caused by noise overexposure. Thus, the purpose of this research was to assess the benefits of simultaneous bilateral laser therapy compared with unilateral laser therapy and a control. Eighteen Sprague-Dawley rats were exposed to narrow-band noise at 115 dB SPL for 6 h. Multiple auditory brainstem responses were measured after each laser irradiation, and cochlear hair cells were counted after the 15th such irradiation. The penetration depth of the 808 nm laser was also measured after sacrifice. Approximately 5% of the laser energy reached the contralateral cochlea. Both bilateral and unilateral laser therapy decreased the hearing threshold after noise overstimulation in the rat model. The bilateral laser therapy group showed faster functional recovery at all tested frequencies compared with the unilateral laser therapy group. However, there was no difference in the endpoint ABR results or final hair cell survival, which was analyzed histologically.

  14. Analysis of Loss of Control Parameters for Aircraft Maneuvering in General Aviation

    Directory of Open Access Journals (Sweden)

    Sameer Ud-Din

    2018-01-01

    Full Text Available A rapid increase in the occurrence of loss of control in general aviation has raised concern in recent years. Loss of control (LOC pertains to unique characteristics in which external and internal events act in conjunction. The Federal Aviation Administration (FAA has approved an Integrated Safety Assessment Model (ISAM for evaluating safety in the National Airspace System (NAS. ISAM consists of an event sequence diagram (ESD with fault trees containing numerous parameters, which is recognized as casual risk model. In this paper, we outline an integrated risk assessment framework to model maneuvering through cross-examining external and internal events. The maneuvering is in the critical flight phase with a high number of LOC occurrences in general aviation, where highly trained and qualified pilots failed to maintain aircraft control irrespective of the preventive nature of the events. Various metrics have been presented for evaluating the significance of these parameters to identify the most important ones. The proposed sensitivity analysis considers the accident, fatality, and risk reduction frequencies that assist in the decision-making process and foresees future risks from a general aviation perspective.

  15. A business perspective on environmental risk and cost reduction

    International Nuclear Information System (INIS)

    Roper, U.V.

    1998-01-01

    The ways in which the petrochemical industry can enjoy successful business partnerships with environmental service companies was discussed. The petrochemical industry has traditionally viewed environmental service companies as an inherent cost in the context of risk management, and not in the context of business opportunity. Today, as environmental issues are integrated into business operations, there is a new potential for creating business opportunities in a number of operational areas, among them : (1) energy efficiency, (2) process efficiency, (3) waste minimization, (4) waste recycling, and (5) operational pooling. As environmental service companies became more competitive, they have become more attractive business partners. They are providing more diversified services and are better aligned with core competencies required to exploit business opportunities that are too small for major players in the oil,natural gas and petro-chemical industry. They also offer public recognition and financial upside for industry. Some examples of successful business partnerships along these lines are briefly described

  16. Energy saving based on the reduction of losses in the transmission and distribution of the power generated incrementing the transmission capacities by means of the use of direct current; Ahorro de energia basado en la reduccion de perdidas en la transmision y redistribucion de la generacion al ampliar las capacidades de transmision por medio del empleo de la transmision en corriente directa

    Energy Technology Data Exchange (ETDEWEB)

    Meraz Ateca, E.; Alanis Rodriguez, J.P.; Salinas Barrera, H.; Arechiga Rodriguez, L.D.; Guerrero Garza, J.J. [Comision Federal de Electricidad (CFE) (Mexico)

    1995-12-31

    This paper proposes the use of the technology for the transmission of direct current that provides a saving in losses in the order of 50% in transmitting the same power as the line energized with A.C., as well as having a larger transmission capacity, since the limiting factor in operating with D.C. is given by its thermal capacity. The cost of the terminal stations is high in comparison with that of A.C., therefore it should be compensated with the benefits of the D.C. transmission. The project proposal is as a first option, to utilize the 400 KV power lines of Carbon II-Lampazos-Escobedo as a single line in Direct Current, reducing by this means about 12% of the existing losses and increasing the existing transmission capacity from the coal power stations of Rio Escondido and Carbon II. For 1995 it will be Also available 2600 MW of generating capacity and practically four circuits of 400 KV to transmit power to the Monterrey Metropolitan Area, reaching this site approximately 1500 MW. It is proposed to transmit 750 MW through the D.C. line in bi-polar way. The investment will consist only in the two conversion stations, that for a power capacity of 750 MW will be in the order of 103 millions of dollars. This cost includes the switching equipment for A.C., filters for harmonics, banks of VARS to compensate for a unit power factor, transformers, converters, ground electrodes, communications, buildings, land site preparation, project management costs and the preliminary and engineering studies costs. These costs can be reduced in accordance with the detail studies, for instance: there is enough capacity in Vars in the generating units, the transmission is always one-way, the utilization of diodes instead of thyristors. For the established conditions, there is a reduction of 10 MW, a 23.82 million dollars saving, and besides a larger Also available transmission capacity in the order of 500 MW, additionally, when operating with direct current, equipment from the

  17. Energy saving based on the reduction of losses in the transmission and distribution of the power generated incrementing the transmission capacities by means of the use of direct current; Ahorro de energia basado en la reduccion de perdidas en la transmision y redistribucion de la generacion al ampliar las capacidades de transmision por medio del empleo de la transmision en corriente directa

    Energy Technology Data Exchange (ETDEWEB)

    Meraz Ateca, E; Alanis Rodriguez, J P; Salinas Barrera, H; Arechiga Rodriguez, L D; Guerrero Garza, J J [Comision Federal de Electricidad (CFE) (Mexico)

    1996-12-31

    This paper proposes the use of the technology for the transmission of direct current that provides a saving in losses in the order of 50% in transmitting the same power as the line energized with A.C., as well as having a larger transmission capacity, since the limiting factor in operating with D.C. is given by its thermal capacity. The cost of the terminal stations is high in comparison with that of A.C., therefore it should be compensated with the benefits of the D.C. transmission. The project proposal is as a first option, to utilize the 400 KV power lines of Carbon II-Lampazos-Escobedo as a single line in Direct Current, reducing by this means about 12% of the existing losses and increasing the existing transmission capacity from the coal power stations of Rio Escondido and Carbon II. For 1995 it will be Also available 2600 MW of generating capacity and practically four circuits of 400 KV to transmit power to the Monterrey Metropolitan Area, reaching this site approximately 1500 MW. It is proposed to transmit 750 MW through the D.C. line in bi-polar way. The investment will consist only in the two conversion stations, that for a power capacity of 750 MW will be in the order of 103 millions of dollars. This cost includes the switching equipment for A.C., filters for harmonics, banks of VARS to compensate for a unit power factor, transformers, converters, ground electrodes, communications, buildings, land site preparation, project management costs and the preliminary and engineering studies costs. These costs can be reduced in accordance with the detail studies, for instance: there is enough capacity in Vars in the generating units, the transmission is always one-way, the utilization of diodes instead of thyristors. For the established conditions, there is a reduction of 10 MW, a 23.82 million dollars saving, and besides a larger Also available transmission capacity in the order of 500 MW, additionally, when operating with direct current, equipment from the

  18. Carbothermic reduction of refractory metals

    International Nuclear Information System (INIS)

    Anderson, R.N.; Parlee, N.A.D.

    1976-01-01

    The reduction of stable refractory metal oxides by carbon is generally unacceptable since the product is usually contaminated with carbides. The carbide formation may be avoided by selecting a solvent metal to dissolve the reactive metal as it is produced and reduce its chemical activity below that required for carbide formation. This approach has been successfully applied to the oxides of Si, Zr, Ti, Al, Mg, and U. In the case where a volatile suboxide, a carbonyl reaction, or a volatile metal occur, the use of the solvent metal appears satisfactory to limit the loss of material at low pressures. In several solute--solvent systems, vacuum evaporation is used to strip the solvent metal from the alloy to give the pure metal

  19. Breaking boundaries for biodiversity : expanding the policy agenda to halt biodiversity loss

    NARCIS (Netherlands)

    Veen, M.P.; Sanders, M.E.; Tekelenburg, A.; Gerritsen, A.L.; Lörzing, J.A.; Brink, Th.

    2010-01-01

    Our assessment from the perspective of the Netherlands, a country in the temperate zone, showed a slightly positive picture, in line with the overall results for this zone. The loss of biodiversity in the Netherlands has been slowed down, but the European target – halting the loss of biodiversity –

  20. Microbial reductive dehalogenation.

    Science.gov (United States)

    Mohn, W W; Tiedje, J M

    1992-01-01

    A wide variety of compounds can be biodegraded via reductive removal of halogen substituents. This process can degrade toxic pollutants, some of which are not known to be biodegraded by any other means. Reductive dehalogenation of aromatic compounds has been found primarily in undefined, syntrophic anaerobic communities. We discuss ecological and physiological principles which appear to be important in these communities and evaluate how widely applicable these principles are. Anaerobic communities that catalyze reductive dehalogenation appear to differ in many respects. A large number of pure cultures which catalyze reductive dehalogenation of aliphatic compounds are known, in contrast to only a few organisms which catalyze reductive dehalogenation of aromatic compounds. Desulfomonile tiedjei DCB-1 is an anaerobe which dehalogenates aromatic compounds and is physiologically and morphologically unusual in a number of respects, including the ability to exploit reductive dehalogenation for energy metabolism. When possible, we use D. tiedjei as a model to understand dehalogenating organisms in the above-mentioned undefined systems. Aerobes use reductive dehalogenation for substrates which are resistant to known mechanisms of oxidative attack. Reductive dehalogenation, especially of aliphatic compounds, has recently been found in cell-free systems. These systems give us an insight into how and why microorganisms catalyze this activity. In some cases transition metal complexes serve as catalysts, whereas in other cases, particularly with aromatic substrates, the catalysts appear to be enzymes. Images PMID:1406492

  1. MENTAL HEALTH: ISLAMIC PERSPECTIVE

    OpenAIRE

    Muzdalifah M. Rahman

    2015-01-01

    The purpose of this paper was to explain the concept of mental health perspective Contemporary Psychology, describes the mental health of an Islamic perspective and describes how mental health recovery. The theory used is the concept of mental health perspective Contemporary Psychology, and the concept of mental health perspective Islamic Psychology Writing is writing method using qualitative research methods. Mental health is avoiding an Islamic perspective of all symptoms, complaints and...

  2. Active3 noise reduction

    International Nuclear Information System (INIS)

    Holzfuss, J.

    1996-01-01

    Noise reduction is a problem being encountered in a variety of applications, such as environmental noise cancellation, signal recovery and separation. Passive noise reduction is done with the help of absorbers. Active noise reduction includes the transmission of phase inverted signals for the cancellation. This paper is about a threefold active approach to noise reduction. It includes the separation of a combined source, which consists of both a noise and a signal part. With the help of interaction with the source by scanning it and recording its response, modeling as a nonlinear dynamical system is achieved. The analysis includes phase space analysis and global radial basis functions as tools for the prediction used in a subsequent cancellation procedure. Examples are given which include noise reduction of speech. copyright 1996 American Institute of Physics

  3. Lymphedema Risk Reduction Practices

    Science.gov (United States)

    ... Question Corner (68) Research (38) Insurance (46) Inspirational Patients (8) LymphLink Articles (174) FAQ's (6) Position Papers (9) LSAP Perspective (9) FOLLOW US! Sign up for our mailing list. twitter Facebook LinkedIn Copyright ©2018 National Lymphedema Network ...

  4. Father Loss and Child Telomere Length.

    Science.gov (United States)

    Mitchell, Colter; McLanahan, Sara; Schneper, Lisa; Garfinkel, Irv; Brooks-Gunn, Jeanne; Notterman, Daniel

    2017-08-01

    Father loss during childhood has negative health and behavioral consequences, but the biological consequences are unknown. Our goal was to examine how father loss (because of separation and/or divorce, death, or incarceration) is associated with cellular function as estimated by telomere length. Data come from the 9-year follow-up of the Fragile Families and Child Wellbeing Study, a birth cohort study of children in 20 large American cities ( N = 2420). Principal measures are as follows: salivary telomere length (sTL), mother reports of father loss, and polymorphisms in genes related to serotonergic and dopaminergic signaling. At 9 years of age, children with father loss have significantly shorter telomeres (14% reduction). Paternal death has the largest association (16%), followed by incarceration (10%), and separation and/or divorce (6%). Changes in income partially mediate these associations (95% mediation for separation and/or divorce, 30% for incarceration, and 25% for death). Effects are 40% greater for boys and 90% greater for children with the most reactive alleles of the serotonin transporter genes when compared with those with the least reactive alleles. No differences were found by age at father loss or a child's race/ethnicity. Father loss has a significant association with children's sTL, with the death of a father showing the largest effect. Income loss explains most of the association between child sTL and separation and/or divorce but much less of the association with incarceration or death. This underscores the important role of fathers in the care and development of children and supplements evidence of the strong negative effects of parental incarceration. Copyright © 2017 by the American Academy of Pediatrics.

  5. Decisions under unpredictable losses

    Directory of Open Access Journals (Sweden)

    Ali Ahmed

    2007-10-01

    Full Text Available An experimental test of the descriptive adequacy of the extit{restated diversification principle} is presented. The principle postulates that risk-averse utility maximizers will pool risks for their mutual benefit, even if information is missing about the probabilities of losses. It is enough for people to assume that they face equal risks when they pool risks. The results of the experiment support the principle.

  6. Understanding Loss Deductions for Timber

    Science.gov (United States)

    John Greene; Michael Jacobson

    1998-01-01

    Forestland owners whose timber has been destroyed may be eligible to take a deduction for the loss on their federal income tax. The loss must be physical in nature and caused by an identifiable event or combination of events that has run its course. There are two types of losses from natural events. Casualty losses are sudden, unexpected, and unusual - as from a fire...

  7. Individual Differences in Loss Aversion: Conscientiousness Predicts How Life Satisfaction Responds to Losses Versus Gains in Income.

    Science.gov (United States)

    Boyce, Christopher J; Wood, Alex M; Ferguson, Eamonn

    2016-04-01

    Loss aversion is considered a general pervasive bias occurring regardless of the context or the person making the decision. We hypothesized that conscientiousness would predict an aversion to losses in the financial domain. We index loss aversion by the relative impact of income losses and gains on life satisfaction. In a representative German sample (N = 105,558; replicated in a British sample, N = 33,848), with conscientiousness measured at baseline, those high on conscientiousness have the strongest reactions to income losses, suggesting a pronounced loss aversion effect, whereas for those moderately unconscientious, there is no loss aversion effect. Our research (a) provides the first evidence of personality moderation of any loss aversion phenomena, (b) supports contextual perspectives that both personality and situational factors need to be examined in combination, (c) shows that the small but robust relationship between income and life satisfaction is driven primarily by a subset of people experiencing highly impactful losses. © 2016 by the Society for Personality and Social Psychology, Inc.

  8. ADT fast losses MD

    CERN Document Server

    Priebe, A; Dehning, B; Redaelli, S; Salvachua Ferrando, BM; Sapinski, M; Solfaroli Camillocci, M; Valuch, D

    2013-01-01

    The fast beam losses in the order of 1 ms are expected to be a potential major luminosity limitation for higher beam energies after the LHC long shutdown (LS1). Therefore a Quench Test is planned in the winter 2013 to estimate the quench limit in this timescale and revise the current models. This experiment was devoted to determination the LHC Transverse Damper (ADT) as a system for fast losses induction. A non-standard operation of the ADT was used to develop the beam oscillation instead of suppressing them. The sign flip method had allowed us to create the fast losses within several LHC turns at 450 GeV during the previous test (26th March 2012). Thus, the ADT could be potentially used for the studies of the UFO ("Unidentied Falling Object") impact on the cold magnets. Verification of the system capability and investigations of the disturbed beam properties were the main objectives of this MD. During the experiment, the pilot bunches of proton beam were excited independently in the horizontal and vertical ...

  9. Lake Nasser evaporation reduction study

    Directory of Open Access Journals (Sweden)

    Hala M.I. Ebaid

    2010-10-01

    Full Text Available This study aims to evaluate the reduction of evaporation of Lake Nasser’s water caused by disconnecting (fully or partially some of its secondary channels (khors. This evaluation integrates remote sensing, Geographic Information System (GIS techniques, aerodynamic principles, and Landsat7 ETM+ images. Three main procedures were carried out in this study; the first derived the surface temperature from Landsat thermal band; the second derived evaporation depth and approximate evaporation volume for the entire lake, and quantified evaporation loss to the secondary channels’ level over one month (March by applied aerodynamic principles on surface temperature of the raster data; the third procedure applied GIS suitability analysis to determine which of these secondary channels (khors should be disconnected. The results showed evaporation depth ranging from 2.73 mm/day at the middle of the lake to 9.58 mm/day at the edge. The evaporated water-loss value throughout the entire lake was about 0.86 billion m3/month (March. The analysis suggests that it is possible to save an approximate total evaporation volume loss of 19.7 million m3/month (March, and thus 2.4 billion m3/year, by disconnecting two khors with approximate construction heights of 8 m and 15 m. In conclusion, remote sensing and GIS are useful for applications in remote locations where field-based information is not readily available and thus recommended for decision makers remotely planning in water conservation and management.

  10. Response to "Learning through Life": Thematic Area of Poverty Reduction

    Science.gov (United States)

    Preece, Julia

    2010-01-01

    This paper responds to the NIACE report "Learning through Life" in relation to the report's thematic area of poverty reduction. The paper draws on the thematic working papers that informed the report as well as wider literature on poverty. It takes a multidimensional perspective of poverty, drawing on Sen's concept of poverty as "unfreedom" and…

  11. International perspective

    International Nuclear Information System (INIS)

    2003-01-01

    The workshop dealt with two distinct cases: - In Port Hope - an existing situation impacting a set of communities affected by the nuclear fuel industry since the 1930's. This situation concerns the remediation of soil 'tainted' by a low level of radioactivity resulting from the processing of uranium. The facility that produced those wastes is still in town but it has changed ownership and it no longer stores or disposes of the waste in the area. - The issuance and upcoming implementation of the Nuclear Fuel Waste Act (NWF Act) charting a path towards the identification of a national, long-term management solution for nuclear fuel (high level) waste in Canada. The NWF Act restarts a process that was interrupted a few years ago, after the Seaborn Environmental Assessment Panel concluded that the solution proposed by proponent Atomic Energy Canada Ltd. had not been demonstrated to have broad public support. From an international perspective, numerous observations can be made and lessons can be drawn both from the individual and the combined cases. Some of the most prominent observations, in the view of the NEA Secretariat, are presented hereafter. (author)

  12. Impact of weight loss on markers of systemic inflammation in obese ...

    African Journals Online (AJOL)

    Background: Weight loss studies were conducted in children without asthma have demonstrated a reduction in systemic inflammation. However, the impact of weight loss in the obese paediatric population with asthma has not been investigated. Objective: To measure the effects of weight loss on markers of systemic ...

  13. Perspectives on Living With Fibromyalgia

    Directory of Open Access Journals (Sweden)

    Ann Gill Taylor

    2016-07-01

    Full Text Available Perceptions of people living with chronic illness change over time, contributing to health-related stress that necessitates coping skills. Paterson’s shifting perspectives model provides an explanation of chronically ill people’s variations in attention to their symptoms. In this qualitative study, 20 people with fibromyalgia living in a rural setting were interviewed in 2013 with the aim of gaining insight into their experiences and the meaning-making associated with their chronic condition. Analysis of the interview data categorized five recurrent, or common, themes: experiences of loss, feelings of fear and uncertainty, influence of stress, stigmatization of the disease, and coping through courage. Difficulties attendant to losses, distress, and stigma associated with this chronic condition led the participants to report poor health-related quality of life. The study findings can be useful across clinical settings to nurses and other health care providers in understanding those diagnosed with fibromyalgia and their care needs.

  14. Blocking Losses With a Photon Counter

    Science.gov (United States)

    Moision, Burce E.; Piazzolla, Sabino

    2012-01-01

    It was not known how to assess accurately losses in a communications link due to photodetector blocking, a phenomenon wherein a detector is rendered inactive for a short time after the detection of a photon. When used to detect a communications signal, blocking leads to losses relative to an ideal detector, which may be measured as a reduction in the communications rate for a given received signal power, or an increase in the signal power required to support the same communications rate. This work involved characterizing blocking losses for single detectors and arrays of detectors. Blocking may be mitigated by spreading the signal intensity over an array of detectors, reducing the count rate on any one detector. A simple approximation was made to the blocking loss as a function of the probability that a detector is unblocked at a given time, essentially treating the blocking probability as a scaling of the detection efficiency. An exact statistical characterization was derived for a single detector, and an approximation for multiple detectors. This allowed derivation of several accurate approximations to the loss. Methods were also derived to account for a rise time in recovery, and non-uniform illumination due to diffraction and atmospheric distortion of the phase front. It was assumed that the communications signal is intensity modulated and received by an array of photon-counting photodetectors. For the purpose of this analysis, it was assumed that the detectors are ideal, in that they produce a signal that allows one to reproduce the arrival times of electrons, produced either as photoelectrons or from dark noise, exactly. For single detectors, the performance of the maximum-likelihood (ML) receiver in blocking is illustrated, as well as a maximum-count (MC) receiver, that, when receiving a pulse-position-modulated (PPM) signal, selects the symbol corresponding to the slot with the largest electron count. Whereas the MC receiver saturates at high count rates

  15. Radiation induced ligand loss from cobalt complexes

    International Nuclear Information System (INIS)

    Funston, A. M.; McFadyen, W.D.; Tregloan, P.A.

    2000-01-01

    Full text: Due to the rapid nature of ligand dissociation from cobalt(II) complexes the study of the rate of ligand dissociation necessitates the use of a technique such as pulse radiolysis. This allows the rapid reduction of the corresponding cobalt(III) complex by a reducing radical, such as the aquated electron, to form the cobalt(II) complex. However, to date, no systematic study of either the mechanism of reduction or the influence of the electronic structure on the rate of ligand dissociation has been carried out. In order to understand these processes more fully the mechanism of reduction of a range of related cobalt(III) complexes by the aquated electron and the subsequent rate of ligand dissociation from the resulting cobalt(II) complexes is being investigated. It has been found that a number of processes are observed following the initial rapid reaction of the cobalt(III) complex with the aquated electron. Ultimately ligand loss is observed. Depending upon the complex, the initial processes observed may include the formation of coordinated radicals and electron transfer within the complex. For complexes containing aromatic ligands such as 2,2'-bipyridine, 1,10-phenanthroline and dipyrido[3,2-a:2',3'-c]phenazine the formation of a coordinated radical is observed as the initial reduction step. The kinetics of ligand dissociation of these complexes has been determined. The loss of monodentate ligands is fast and has been indistinguishable from the reduction processes when aromatic ligands are also present in the complex. However, for diamine chelates and diimine chelates spectra of the transient species can be resolved

  16. Potential for waste reduction

    International Nuclear Information System (INIS)

    Warren, J.L.

    1990-01-01

    The author focuses on wastes considered hazardous under the Resource Conservation and Recovery Act. This chapter discusses wastes that are of interest as well as the factors affecting the quantity of waste considered available for waste reduction. Estimates are provided of the quantities of wastes generated. Estimates of the potential for waste reduction are meaningful only to the extent that one can understand the amount of waste actually being generated. Estimates of waste reduction potential are summarized from a variety of government and nongovernment sources

  17. Loss of GABAergic inputs in APP/PS1 mouse model of Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Tutu Oyelami

    2014-04-01

    Full Text Available Alzheimer's disease (AD is characterized by symptoms which include seizures, sleep disruption, loss of memory as well as anxiety in patients. Of particular importance is the possibility of preventing the progressive loss of neuronal projections in the disease. Transgenic mice overexpressing EOFAD mutant PS1 (L166P and mutant APP (APP KM670/671NL Swedish (APP/PS1 develop a very early and robust Amyloid pathology and display synaptic plasticity impairments and cognitive dysfunction. Here we investigated GABAergic neurotransmission, using multi-electrode array (MEA technology and pharmacological manipulation to quantify the effect of GABA Blockers on field excitatory postsynaptic potentials (fEPSP, and immunostaining of GABAergic neurons. Using MEA technology we confirm impaired LTP induction by high frequency stimulation in APPPS1 hippocampal CA1 region that was associated with reduced alteration of the pair pulse ratio after LTP induction. Synaptic dysfunction was also observed under manipulation of external Calcium concentration and input-output curve. Electrophysiological recordings from brain slice of CA1 hippocampus area, in the presence of GABAergic receptors blockers cocktails further demonstrated significant reduction in the GABAergic inputs in APP/PS1 mice. Moreover, immunostaining of GAD65 a specific marker for GABAergic neurons revealed reduction of the GABAergic inputs in CA1 area of the hippocampus. These results might be linked to increased seizure sensitivity, premature death and cognitive dysfunction in this animal model of AD. Further in depth analysis of GABAergic dysfunction in APP/PS1 mice is required and may open new perspectives for AD therapy by restoring GABAergic function.

  18. Loss-Aversion or Loss-Attention: The Impact of Losses on Cognitive Performance

    Science.gov (United States)

    Yechiam, Eldad; Hochman, Guy

    2013-01-01

    Losses were found to improve cognitive performance, and this has been commonly explained by increased weighting of losses compared to gains (i.e., loss aversion). We examine whether effects of losses on performance could be modulated by two alternative processes: an attentional effect leading to increased sensitivity to task incentives; and a…

  19. Criteria for achieving actinide reduction goals

    International Nuclear Information System (INIS)

    Liljenzin, J.O.

    1996-01-01

    In order to discuss various criteria for achieving actinide reduction goals, the goals for actinide reduction must be defined themselves. In this context the term actinides is interpreted to mean plutonium and the so called ''minor actinides'' neptunium, americium and curium, but also protactinium. Some possible goals and the reasons behind these will be presented. On the basis of the suggested goals it is possible to analyze various types of devices for production of nuclear energy from uranium or thorium, such as thermal or fast reactors and accelerator driven system, with their associated fuel cycles with regard to their ability to reach the actinide reduction goals. The relation between necessary single cycle burn-up values, fuel cycle processing losses and losses to waste will be defined and discussed. Finally, an attempt is made to arrange the possible systems on order of performance with regard to their potential to reduce the actinide inventory and the actinide losses to wastes. (author). 3 refs, 3 figs, 2 tabs

  20. Women's challenges with postpartum weight loss.

    Science.gov (United States)

    Montgomery, Kristen S; Bushee, Tracy D; Phillips, Jennifer D; Kirkpatrick, Terrie; Catledge, Courtney; Braveboy, Kristin; O'Rourke, Carol; Patel, Neema; Prophet, Malshundria; Cooper, Anita; Mosley, Lori; Parker, Christie; Douglas, Gaye M

    2011-11-01

    This study was designed to examine women's experiences of weight loss during the postpartum period. Understanding women's positive and negative experiences can assist health care providers to successfully intervene in helping women lose weight following pregnancy and avoid long-term weight gain and obesity development. Phenomenology, according to Husserl's perspective. Private location of the women's choosing. Twenty-six women, who ranged in age from 25 to 35 years, and had given birth within the last 5 years, were interviewed regarding their experiences with postpartum weight loss. The majority of the sample was Caucasian. Interviews were transcribed and themes were identified from each of the interviews. Comparisons were made between interviews to identify common experiences between women. Data were analyzed according to the Giorgi method. The women in the study had a wide range of experiences. Themes that emerged from the interviews related to women's challenges with return to prepregnancy weight. These included: time and motivation issues, the need for support, and weight and other struggles. This study provides a look inside the lives of women faced with the reality of losing weight after childbirth. Losing weight after delivery is multi-faceted and influenced by many factors. Interventions to assist women with weight loss should target the challenges described in this paper. When effective strategies are developed, education can be done during pregnancy to prepare for the postpartum period. Ultimately, future research efforts can help us to eliminate pregnancy as a risk factor for obesity in women.

  1. Distribution grid reconfiguration reduces power losses and helps integrate renewables

    International Nuclear Information System (INIS)

    Lueken, Colleen; Carvalho, Pedro M.S.; Apt, Jay

    2012-01-01

    A reconfigurable network can change its topology by opening and closing switches on power lines. We use real wind, solar, load, and cost data and a model of a reconfigurable distribution grid to show that reconfiguration allows a grid operator to reduce operational losses as well as to accept more intermittent renewable generation than a static configuration can. Net present value analysis of automated switch technology shows that the return on investment is negative for this test network when considering only loss reduction, but that the investment is attractive under certain conditions when reconfiguration is used to minimize curtailment. - Highlights: ► Reconfiguration may reduce losses in grids with solar or wind distributed generation. ► Reconfigurable networks can accept more solar or wind DG than static ones. ► Using reconfiguration for loss reduction would not create a positive ROI. ► Using reconfiguration to reduce curtailment usually would create a positive ROI.

  2. Breast reduction (mammoplasty) - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100189.htm Breast reduction (mammoplasty) - series—Indications To use the sharing features ... Lickstein, MD, FACS, specializing in cosmetic and reconstructive plastic surgery, Palm Beach Gardens, FL. Review provided by ...

  3. Medical Errors Reduction Initiative

    National Research Council Canada - National Science Library

    Mutter, Michael L

    2005-01-01

    The Valley Hospital of Ridgewood, New Jersey, is proposing to extend a limited but highly successful specimen management and medication administration medical errors reduction initiative on a hospital-wide basis...

  4. Historical perspective

    International Nuclear Information System (INIS)

    Davis, E.M.

    1982-01-01

    A historical perspective of the nuclear waste issue is presented, beginning from the Atoms for Peace Legislation which made nuclear technology available to private industry in 1953 to 1954. Once the nuclear process had been demonstrated to be a technically and economically feasible method to convert thermal energy for electric power generation, commercial application began. The issue of nuclear waste management did not keep up with higher priorities. As early as 1957, research into storing the waste in geological structures was conducted by the National Academy of Sciences, and considerable technical progress was made in the 60's. During the 60's and 70's, numerous legislative actions (e.g., Clean Air Act, Clean Water Act, Environmental Policy Act) had a significant impact on nuclear waste dipsosal decisions. In 1971 to 1972 the Atomic Energy Commission authorized a nuclear waste repository in Kansas, a decision which was amended the following year and finally abandoned altogether in 1974. The OPEC oil embargo and ensuing price actions moved nuclear power into a more prominent position in the United States' plans for energy independence. This increased the stress between environmental concerns and economic need. The Carter Administration indefinitely deferred reprocessing of spent fuel and initiated a government-wide review of nuclear policy issues. The Congress did not actively begin to fashion a nuclear waste program until February 1980. The legislation which passed the Senate in the Spring of '82, and a compromise version pending before the House, may resolve the issue by establishing a long-term stable policy which will contain milestones, goals and specific decision making processes; it will include a mechanism for the public and the states to be involved; and it will insure adequate financing provisions

  5. Microbial reductive dehalogenation.

    OpenAIRE

    Mohn, W W; Tiedje, J M

    1992-01-01

    A wide variety of compounds can be biodegraded via reductive removal of halogen substituents. This process can degrade toxic pollutants, some of which are not known to be biodegraded by any other means. Reductive dehalogenation of aromatic compounds has been found primarily in undefined, syntrophic anaerobic communities. We discuss ecological and physiological principles which appear to be important in these communities and evaluate how widely applicable these principles are. Anaerobic commun...

  6. Air Layer Drag Reduction

    Science.gov (United States)

    Ceccio, Steven; Elbing, Brian; Winkel, Eric; Dowling, David; Perlin, Marc

    2008-11-01

    A set of experiments have been conducted at the US Navy's Large Cavitation Channel to investigate skin-friction drag reduction with the injection of air into a high Reynolds number turbulent boundary layer. Testing was performed on a 12.9 m long flat-plate test model with the surface hydraulically smooth and fully rough at downstream-distance-based Reynolds numbers to 220 million and at speeds to 20 m/s. Local skin-friction, near-wall bulk void fraction, and near-wall bubble imaging were monitored along the length of the model. The instrument suite was used to access the requirements necessary to achieve air layer drag reduction (ALDR). Injection of air over a wide range of air fluxes showed that three drag reduction regimes exist when injecting air; (1) bubble drag reduction that has poor downstream persistence, (2) a transitional regime with a steep rise in drag reduction, and (3) ALDR regime where the drag reduction plateaus at 90% ± 10% over the entire model length with large void fractions in the near-wall region. These investigations revealed several requirements for ALDR including; sufficient volumetric air fluxes that increase approximately with the square of the free-stream speed, slightly higher air fluxes are needed when the surface tension is reduced, higher air fluxes are required for rough surfaces, and the formation of ALDR is sensitive to the inlet condition.

  7. Treatment of Obesity: Weight Loss and Bariatric Surgery

    Science.gov (United States)

    Wolfe, Bruce M.; Kvach, Elizaveta; Eckel, Robert H.

    2016-01-01

    This review focuses on the mechanisms underlying, and indications for, bariatric surgery in the reduction of cardiovascular disease (CVD) as well as other expected benefits of this intervention. The fundamental basis for bariatric surgery for the purpose of accomplishing weight loss is the determination that severe obesity is a disease associated with multiple adverse effects on health which can be reversed or improved by successful weight loss in patients who have been unable to sustain weight loss by non-surgical means. An explanation of possible indications for weight loss surgery as well as specific bariatric surgical procedures is presented, along with review of the safety literature of such procedures. Procedures that are less invasive or those that involve less gastrointestinal rearrangement accomplish considerably less weight loss but have substantially lower perioperative and longer-term risk. The ultimate benefit of weight reduction relates to the reduction of the co-morbidities, quality of life and all-cause mortality. With weight loss being the underlying justification for bariatric surgery in ameliorating CVD risk, current evidence-based research is discussed concerning body fat distribution, dyslipidemia, hypertension, diabetes, inflammation, obstructive sleep apnea and others. The rationale for bariatric surgery reducing CVD events is discussed and juxtaposed with impacts on all-cause mortalities. Given the improvement of established obesity-related CVD risk factors following weight loss, it is reasonable to expect a reduction of CVD events and related mortality following weight loss in populations with obesity. The quality of the current evidence is reviewed and future research opportunities and summaries are stated. PMID:27230645

  8. Zonisamide-induced weight loss in schizophrenia: case series.

    Science.gov (United States)

    Yang, Jaewon; Lee, Moon-Soo; Joe, Sook-Haeng; Jung, In-Kwa; Kim, Seung-Hyun

    2010-01-01

    Weight gain and metabolic disturbances constitute bothersome problems in schizophrenic patients treated with atypical antipsychotics. Several medications, exercise regimens, and lifestyle changes have been used in attempts to ameliorate these problems. We describe 3 patients with schizophrenia who manifested distinct weight loss and reduction in waist circumference during medication with zonisamide. This report suggests that zonisamide might be associated with weight loss in patients with schizophrenia.

  9. Female pattern alopecia: current perspectives

    Directory of Open Access Journals (Sweden)

    Levy LL

    2013-08-01

    Full Text Available Lauren L Levy, Jason J Emer Department of Dermatology, Mount Sinai School of Medicine, New York, NY, USA Abstract: Hair loss is a commonly encountered problem in clinical practice, with men presenting with a distinctive pattern involving hairline recession and vertex balding (Norwood-Hamilton classification and women exhibiting diffuse hair thinning over the crown (increased part width and sparing of the frontal hairline (Ludwig classification. Female pattern hair loss has a strikingly overwhelming psychological effect; thus, successful treatments are necessary. Difficulty lies in successful treatment interventions, as only two medications – minoxidil and finasteride – are approved for the treatment of androgenetic alopecia, and these medications offer mediocre results, lack of a permanent cure, and potential complications. Hair transplantation is the only current successful permanent option, and it requires surgical procedures. Several other medical options, such as antiandrogens (eg, spironolactone, oral contraceptives, cyproterone, flutamide, dutasteride, prostaglandin analogs (eg, bimatoprost, latanoprost, and ketoconazole are reported to be beneficial. Laser and light therapies have also become popular despite the lack of a profound benefit. Management of expectations is crucial, and the aim of therapy, given the current therapeutic options, is to slow or stop disease progression with contentment despite patient expectations of permanent hair regrowth. This article reviews current perspectives on therapeutic options for female pattern hair loss. Keywords: androgenetic alopecia, female pattern hair loss, minoxidil, finasteride, antiandrogens, spironolactone

  10. Reduct Driven Pattern Extraction from Clusters

    Directory of Open Access Journals (Sweden)

    Shuchita Upadhyaya

    2009-03-01

    Full Text Available Clustering algorithms give general description of clusters, listing number of clusters and member entities in those clusters. However, these algorithms lack in generating cluster description in the form of pattern. From data mining perspective, pattern learning from clusters is as important as cluster finding. In the proposed approach, reduct derived from rough set theory is employed for pattern formulation. Further, reduct are the set of attributes which distinguishes the entities in a homogenous cluster, hence these can be clear cut removed from the same. Remaining attributes are then ranked for their contribution in the cluster. Pattern is formulated with the conjunction of most contributing attributes such that pattern distinctively describes the cluster with minimum error.

  11. Acceptable losses: the debatable origins of loss aversion.

    Science.gov (United States)

    Yechiam, Eldad

    2018-04-16

    It is often claimed that negative events carry a larger weight than positive events. Loss aversion is the manifestation of this argument in monetary outcomes. In this review, we examine early studies of the utility function of gains and losses, and in particular the original evidence for loss aversion reported by Kahneman and Tversky (Econometrica  47:263-291, 1979). We suggest that loss aversion proponents have over-interpreted these findings. Specifically, the early studies of utility functions have shown that while very large losses are overweighted, smaller losses are often not. In addition, the findings of some of these studies have been systematically misrepresented to reflect loss aversion, though they did not find it. These findings shed light both on the inability of modern studies to reproduce loss aversion as well as a second literature arguing strongly for it.

  12. Robust loss functions for boosting.

    Science.gov (United States)

    Kanamori, Takafumi; Takenouchi, Takashi; Eguchi, Shinto; Murata, Noboru

    2007-08-01

    Boosting is known as a gradient descent algorithm over loss functions. It is often pointed out that the typical boosting algorithm, Adaboost, is highly affected by outliers. In this letter, loss functions for robust boosting are studied. Based on the concept of robust statistics, we propose a transformation of loss functions that makes boosting algorithms robust against extreme outliers. Next, the truncation of loss functions is applied to contamination models that describe the occurrence of mislabels near decision boundaries. Numerical experiments illustrate that the proposed loss functions derived from the contamination models are useful for handling highly noisy data in comparison with other loss functions.

  13. Loss Aversion and Individual Characteristics

    DEFF Research Database (Denmark)

    Hjorth, Katrine; Fosgerau, Mogens

    2011-01-01

    Many studies have shown that loss aversion affects the valuation of non-market goods. Using stated choice data, this paper presents an empirical investigation of how individual-level loss aversion varies with observable personal characteristics and with the choice context. We investigate loss...... aversion with respect to travel time and money, and find significant loss aversion in both dimensions. The degree of loss aversion in the time dimension is larger than in the money dimension, and depends on age and education. Subjects tend to be more loss averse when the reference is well established....

  14. Hair loss and hyperprolactinemia in women

    Science.gov (United States)

    2012-01-01

    In the literature of the past 30 years there are only some publications concerned with hair loss and hyperprolactinemia in women. Therefore, the relevance of hyperprolactinemia was evaluated in 40 women with diffuse alopecia. Hair loss was assessed by clinical appearance and the pluck trichogram. 82.5% of the female patients had diffuse hair loss and 17.5% had androgenetic alopecia. The highest prolactin values measured were 1390 ng/ml and 255 ng/ml. Six patients had values between 150–80.4 ng/ml and 10 between 79.1–51.7 ng/ml. All others had prolactin values below 50 ng/ml. Fifteen untreated patients with elevated prolactin levels could be followed up. Without any prolactin-inhibiting drugs, reductions and normalizations beside moderate fluctuations could be detected. Thyroid-specific diagnostics showed in 95% of the patients a normal thyroid function. 2.5% had a slight hyperthyreoidism and 2.5% had a slight hypothyreoidism. No female patient had clinical signs of androgenization and the determined androgens testosterone, androstendione and dihydroepiandrostendione were in the normal range. According to these results, moderate elevated prolactin levels in association with diffuse or androgenetic hair loss can be neglected as causative for the hair loss, because there is no evidence that they have an influence to the pattern, the extent or the duration of the hair loss. These results are supported by investigations of other authors who described only in high doses of prolactin an inhibiting effect on human hair follicles in vitro. Nevertheless, moderate constantly elevated prolactin levels should induce further diagnostics to exclude a prolactin-producing tumor of the pituitary gland. PMID:22870355

  15. Tragic loss at CERN

    CERN Multimedia

    CERN Ski Club

    2015-01-01

    Tragic loss at CERN The CERN community is mourning the tragic loss of two members of the CERN Ski Club. On Sunday, April 12, an avalanche buried four out of five skiers, taking part in a ski touring in the region of the Becs de Bosson in Valais (CH). The fifth skier, who had not been buried in the snow,  courageously managed to save two of the skiers, but Hervé Milcent, 49 years, federal ski instructor, and Mattieu Cattin, 33 years, were buried under two to three meters of snow, far down the avalanche slope, and did not survive, despite the fast arrival of the mountain rescue. In its 40 years of existence, the CERN Ski Club, one of the biggest in the Geneva area, has never been confronted with such a tragedy. The passing of Hervé and Matthieu has deeply shocked and saddened all volunteers of the Club as well as the entire alpine community. The ski touring section of the club would like to honour its friend Hervé, who joined the club in 1998. In 2003 he became res...

  16. Female Pattern Hair Loss

    Science.gov (United States)

    Herskovitz, Ingrid; Tosti, Antonella

    2013-01-01

    Context: Female pattern hair loss (FPHL) also known as female androgenetic alopecia is a common condition afflicting millions of women that can be cosmetically disrupting. Prompt diagnosis and treatment are essential for obtaining optimal outcome. This review addresses the clinical presentation of female pattern hair loss, its differential diagnosis and treatment modalities. Evidence Acquisition: A) Diffuse thinning of the crown region with preservation of the frontal hairline (Ludwig’s type) B) The “Christmas tree pattern” where the thinning is wider in the frontal scalp giving the alopecic area a triangular shaped figure resembling a christmas tree. C) Thinning associated with bitemporal recession (Hamilton type). Generally, FPHL is not associated with elevated androgens. Less commonly females with FPHL may have other skin or general signs of hyperandrogenism such as hirsutism, acne, irregular menses, infertility, galactorrhea and insulin resistance. The most common endocrinological abnormality associated with FPHL is polycystic ovarian syndrome (PCOS). Results: The most important diseases to consider in the differential diagnosis of FPHL include Chronic Telogen Effluvium (CTE), Permanent Alopecia after Chemotherapy (PAC), Alopecia Areata Incognito (AAI) and Frontal Fibrosing Alopecia (FFA). This review describes criteria for distinguishing these conditions from FPHL. Conclusions: The only approved treatment for FPHL, which is 2% topical Minoxidil, should be applied at the dosage of 1ml twice day for a minimum period of 12 months. This review will discuss off-label alternative modalities of treatment including 5-alfa reductase inhibitors, antiandrogens, estrogens, prostaglandin analogs, lasers, light treatments and hair transplantation. PMID:24719635

  17. Female pattern hair loss.

    Science.gov (United States)

    Herskovitz, Ingrid; Tosti, Antonella

    2013-10-01

    Female pattern hair loss (FPHL) also known as female androgenetic alopecia is a common condition afflicting millions of women that can be cosmetically disrupting. Prompt diagnosis and treatment are essential for obtaining optimal outcome. This review addresses the clinical presentation of female pattern hair loss, its differential diagnosis and treatment modalities. A) Diffuse thinning of the crown region with preservation of the frontal hairline (Ludwig's type) B) The "Christmas tree pattern" where the thinning is wider in the frontal scalp giving the alopecic area a triangular shaped figure resembling a christmas tree. C) Thinning associated with bitemporal recession (Hamilton type). Generally, FPHL is not associated with elevated androgens. Less commonly females with FPHL may have other skin or general signs of hyperandrogenism such as hirsutism, acne, irregular menses, infertility, galactorrhea and insulin resistance. The most common endocrinological abnormality associated with FPHL is polycystic ovarian syndrome (PCOS). The most important diseases to consider in the differential diagnosis of FPHL include Chronic Telogen Effluvium (CTE), Permanent Alopecia after Chemotherapy (PAC), Alopecia Areata Incognito (AAI) and Frontal Fibrosing Alopecia (FFA). This review describes criteria for distinguishing these conditions from FPHL. The only approved treatment for FPHL, which is 2% topical Minoxidil, should be applied at the dosage of 1ml twice day for a minimum period of 12 months. This review will discuss off-label alternative modalities of treatment including 5-alfa reductase inhibitors, antiandrogens, estrogens, prostaglandin analogs, lasers, light treatments and hair transplantation.

  18. Coping proactively with economic stress: career adaptability in the face of job insecurity, job loss, unemployment, and underemployment

    NARCIS (Netherlands)

    Klehe, U.-C.; Zikic, J.; van Vianen, A.E.M.; Koen, J.; Buyken, M.; Perrewé, P.L; Halbesleben, J.R.B.; Rosen, C.C.

    2012-01-01

    Economic stressors such as job insecurity, job loss, unemployment, and underemployment cause severe difficulties for the workers affected, their families, organizations, and societies overall. Consequently, most past research has taken a thoroughly negative perspective on economic stress, addressing

  19. Judged seriousness of environmental losses: reliability and cause of loss

    Science.gov (United States)

    Thomas C. Brown; Dawn Nannini; Robert B. Gorter; Paul A. Bell; George L. Peterson

    2002-01-01

    Public judgments of the seriousness of environmental losses were found to be internally consistent for most respondents, and largely unaffected by attempts to manipulate responses by altering the mix of losses being judged. Both findings enhance confidence in the feasibility of developing reliable rankings of the seriousness of environmental losses to aid resource...

  20. Insertion Loss of Personal Protective Clothing

    International Nuclear Information System (INIS)

    Shull, D.J.

    1999-01-01

    The use of personal protective clothing that covers the head is a common practice in many industries. Such personal protective clothing will impact the sound pressure level and the frequency content of sounds to which the wearer will be exposed. The use of such clothing, then, may impact speech and alarm audibility. A measure of the impact of such clothing is its insertion loss. Insertion loss measurements were performed on four types of personal protective clothing in use by Westinghouse Savannah River Company personnel which utilize cloth and plastic hood configurations to protect the head. All clothing configurations tested at least partially cover the ears. The measurements revealed that insertion loss of the items tested was notable at frequencies above 1000 Hz only and was a function of material stiffness and acoustic flanking paths to the ear. Further, an estimate of the clothing's noise reduction rating reveals poor performance in that regard, even though the insertion loss of the test articles was significant at frequencies at and above 1000 Hz.'

  1. Determination of bore efficiency loss employed as powder in boral fabrication, proportionately to the dimension of grain; Determination de la reduction d'efficacite du bore ou d'un autre absorbeur employe sous forme de poudre dissemine dans un produit non absorbant, en fonction de la grosseur des grains

    Energy Technology Data Exchange (ETDEWEB)

    Laforge, P; Millot, J P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1957-07-01

    Authors' mind was attracted by the importance of bore granulometry when employed as powder in boral fabrication. The calculation, object of this report, permits to give values for bore efficiency loss, proportionately to the dimension of spherical or ellipsoidal supposed grains. Grains to be employed should exceptionally only exceed 20 {mu} for a correspondent efficiency loss of 8 per cent about. (author) [French] L'attention des auteurs a ete attiree sur l'importance de la granulometrie du bore employe sous forme de poudre dans la fabrication du boral. Le calcul qui fait l'objet de ce rapport permet de chiffrer la perte d'efficacite du bore en fonction de la dimension des grains supposes spheriques ou ellipsoidaux. Les grains a employer ne devraient qu'exceptionnellement etre superieurs a 20 microns, ce qui correspond a une perte d'efficacite d'environ 8 pour cent. (auteur)

  2. Noise-Induced Hearing Loss

    Science.gov (United States)

    ... Home » Health Info » Hearing, Ear Infections, and Deafness Noise-Induced Hearing Loss On this page: What is ... I find additional information about NIHL? What is noise-induced hearing loss? Every day, we experience sound ...

  3. Noise and Hearing Loss Prevention

    Science.gov (United States)

    ... message, please visit this page: About CDC.gov . NOISE AND HEARING LOSS PREVENTION Language: English (US) Español ( ... when hazardous noise levels cannot be adequately reduced. Noise and Hearing Loss on the NIOSH Science Blog ...

  4. Age-related hearing loss

    Science.gov (United States)

    ... grow older. Your genes and loud noise (from rock concerts or music headphones) may play a large role. The following factors contribute to age-related hearing loss: Family history (age-related hearing loss tends to run in ...

  5. Overweight, Obesity, and Weight Loss

    Science.gov (United States)

    ... Back to section menu Healthy Weight Weight and obesity Underweight Weight, fertility, and pregnancy Weight loss and ... section Home Healthy Weight Healthy Weight Weight and obesity Underweight Weight, fertility, and pregnancy Weight loss and ...

  6. Hearing Loss: Symptoms, Diagnosis & Treatment

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Hearing Loss Symptoms, Devices, Prevention & Research Past Issues / Spring ... a disease. It can accompany any type of hearing loss. It can be a side effect of ...

  7. Breast Cancer and Bone Loss

    Science.gov (United States)

    ... Menopause Map Featured Resource Find an Endocrinologist Search Breast Cancer and Bone Loss July 2010 Download PDFs English ... G. Komen Foundation What is the link between breast cancer and bone loss? Certain treatments for breast cancer ...

  8. A.C. losses in current-carrying superconductors

    International Nuclear Information System (INIS)

    Reuver, J.L. de.

    1985-01-01

    The feasibility of superconductors for alternating current use depends on successful reduction of losses. Moreover, the demand for large field amplitudes is a stimulation for investigating the nature of a.c. losses (e.g. in the set of poloidal coils in a TOKAMAK). In this thesis, measurements are performed at a.c. superconductivity. Attention is given to various external field conditions as well as to self-field instability. Measurements are performed on different types of wires. A type of wire is searched for with both low losses and a good stabilization under self-field conditions. (G.J.P.)

  9. Minimization of Distribution Grid Losses by Consumption Coordination

    DEFF Research Database (Denmark)

    Juelsgaard, Morten; Andersen, Palle; Wisniewski, Rafal

    2013-01-01

    for coordinating consumption of electrical energy within the community, with the purpose of reducing grid loading and active power losses. For this we present a simplified model of the electrical grid, including system losses and capacity constraints. Coordination is performed in a distributed fashion, where each...... are obeyed. These objectives are enforced by coordinating consumers through nonlinear tariffs on power consumption. We present simulation test-cases, illustrating that significant reduction of active losses, can be obtained by such coordination. The distributed optimization algorithm, employs the alternating...

  10. International decade for natural disaster reduction

    Science.gov (United States)

    Hays, W. W.

    1990-01-01

    Throughout history, humanity has found itself in conflict with naturally occurring events of geologic, hydrologic, and atmospheric origin. this conflict has been demonstrated repeatedly when people build urban centers at the water's edge, in or near active fault systems capable of generating earthquakes, on steep slopes, near active volcanoes, or at the urban-wilderness interface prone to wildfires. Naturally occurring, recurrent events such as floods, windstorms, tsunamis, earthquakes, landslides, volcanic eruptions, and wildfires have tested human-engineered works many times and have often found them unable to withstand the forces generated by the event. In the past 20 years, for example, events like these throughout the world have claimed more than 2.8 million lives and adversely affected 820 million people; single disasters have caused economic losses of billions of dollars. Industrialized countries like the United States and Japan have been able to absorb the socioeconomic losses of past natural disasters, but the economics of many developing countries have been devastated by losses equal to a large percentage of their gross national product. Furthermore, the magnitude of the losses is increasing at a rapid rate as the building wealth of nations is expanded to meet the needs of rapidly increasing population, often without adequate consideration of the potential threat posed by the recurrent natural hazards and without implementing effective loss-reduction measures because of lack of knowledge or lack of technical capability. 

  11. Quantification of surgical blood loss.

    Science.gov (United States)

    Lee, Marcel H; Ingvertsen, Britt T; Kirpensteijn, Jolle; Jensen, Asger L; Kristensen, Annemarie T

    2006-06-01

    To compare gravimetric and colorimetric methods of quantifying surgical blood loss, and to determine if there is a correlation between preoperative hemostatic tests (buccal mucosa bleeding time [BMBT] and intraoperative blood loss). Prospective clinical study. Dogs (n=15) admitted for cutaneous tumor excision, orthopedic procedure, or exploratory laparotomy. Intraoperative blood loss was quantified by measuring irrigation fluid and weighing surgical sponges used for blood and fluid collection during surgery. Results of gravimetric measurements were then correlated to blood loss quantified using spectrophotometric analysis of hemoglobin (Hb) content. Hemostatic variables including BMBT were measured before surgery and compared with the calculated amount of blood loss. Blood loss quantified by gravimetric measurement showed a significant correlation with colorimetric determination of Hb content in surgical sponges and collected irrigation fluid (r=0.93, P<.0001). BMBT correlated weakly but significantly with intraoperative blood loss (r=0.56, P<.05). Quantifying intraoperative blood loss using spectrophotometric Hb analysis accurately assessed the amount of blood loss; however, it is a time-consuming procedure, primarily applicable as a research tool. Gravimetric evaluation of intraoperative blood loss was found to be an accurate method, which can be recommended for use in a clinical setting. Estimation of blood loss using a gravimetric method is accurate and applicable in the clinical setting and provides surgeons with a simple and objective tool to evaluate intraoperative blood loss.

  12. Retroactive Stop Loss Special Pay

    Science.gov (United States)

    Pay (RSLSP), providing $500 for each month/partial month served in stop loss status. Service members served under stop loss must submit a claim for the special pay. Throughout the year, the services have or extension of service, became ineligible to receive retroactive stop loss special pay. There may be

  13. Losses compensation; Compensation des pertes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    One mission of RTE (Electric Power Transportation), is to watch over the losses compensation resulting from the power transport on the electric power network. Since january 2001, RTE makes good the electric losses by the purchase of energy. To choose the marketers, a consultation has been realized by RTE. This document presents the rules concerning these losses compensation. (A.L.B.)

  14. Hypnotherapy in Weight Loss Treatment.

    Science.gov (United States)

    Cochrane, Gordon; Friesen, John

    1986-01-01

    Investigated effects of hypnosis as a treatment for weight loss among women. The primary hypothesis that hypnosis is an effective treatment for weight loss was confirmed, but seven concomitant variables and the use of audiotapes were not significant contributors to weight loss. (Author/ABB)

  15. Measuring mandibular ridge reduction

    International Nuclear Information System (INIS)

    Steen, W.H.A.

    1984-01-01

    This thesis investigates the mandibular reduction in height of complete denture wearers and overdenture wearers. To follow this reduction in the anterior region as well as in the lateral sections of the mandible, an accurate and reproducible measuring method is a prerequisite. A radiologic technique offers the best chance. A survey is given of the literature concerning the resorption process after the extraction of teeth. An oblique cephalometric radiographic technique is introduced as a promising method to measure mandibular ridge reduction. The reproducibility and the accuracy of the technique are determined. The reproducibility in the positioning of the mandible is improved by the introduction of a mandibular support which permits a precise repositioning of the edentulous jaw, even after long periods of investigation. (Auth.)

  16. Stakeholder perspectives on carbon capture and storage in Indonesia

    International Nuclear Information System (INIS)

    Setiawan, Andri D.; Cuppen, Eefje

    2013-01-01

    Carbon capture and storage (CCS) is being considered as an option to reduce CO 2 emissions worldwide. Yet recent cases show that CCS faces divergent public acceptance issues. This paper investigates stakeholder perspectives on CCS in Indonesia. Q methodology was adopted to analyse the diversity of stakeholder perspectives. Four perspectives were identified: (1) “CO 2 emissions reduction through clean energy sources rather than CCS”; (2) “CCS as one of the options in the transition to a sustainable energy system”; (3) “CCS as the only optimal solution to reduce CO 2 emissions”; (4) “CCS is only a tactic to keep burning coal forever”. Based on these results, we argue that stakeholder acceptance of CCS should be understood as a complex notion. This means that understanding whether or under what conditions stakeholders would be willing to support CCS, requires consideration of stakeholders' viewpoints about broader questions of CO 2 emission reduction and energy supply in Indonesia, rather than studying attitudes towards CCS in isolation. We discuss how the approach taken in this study can be used and followed up in policymaking on CCS in Indonesia. - Highlights: • We investigate stakeholder perspectives on CCS in Indonesia with Q methodology. • The study revealed four shared perspectives on CCS in Indonesia. • Of the four perspectives, two are contrasting perspectives: one pro and one con CCS. • The other two are nuanced perspectives and differ in their argumentation on CCS. • From these results we derive academic and policy implications

  17. France: energetic perspectives for 2050

    International Nuclear Information System (INIS)

    Acket, C.; Bacher, P.

    2011-01-01

    The author reports the study of four simple scenarios to examine the French perspectives regarding energy consumption, sources and production. First, he comments the differences which appear between published data predicting the world energy production in 2050. He outlines the need of important energy savings and of reduction of the share of fossil energies and of CO 2 emissions. Then he discusses the French perspectives according to four scenarios which are characterized by their average growth rate for electricity with an objective of reduction of the share of fossil energies (division by 4). He discusses energy saving opportunities in different sectors (housing and office buildings, mobility and transports, food and industry), and also how to make evolve the share of the different energy sources for these sectors. He discusses various possibilities for the development of renewable energies, and the future of nuclear energy. He comes back to the four scenarios and qualifies them: underlying, moderate consumption, carrying on nuclear energy production, going out of nuclear

  18. Science and technology perspective

    International Nuclear Information System (INIS)

    Knotek, M.L.

    1993-01-01

    This paper looks at the waste processing program for Hanford from the perspective of science and technology. The Hanford waste processing problem is but one phase of the total defense waste problem in the country, and a small part of the total waste disposal problem of the industrial base of the country. Basic research effort on this problem will address the specific problems encountered in the forms of this waste, but will also develop technology of use to the entire industrial base of the country, while at the same time trying to benefit from technology being developed in this industrial base. The Hanford waste represents a huge financial cost in terms of its present volume, if handled by the proposed methods of grouting and vitrification. To decrease this costs technology will have to come forward with new processes which result in the overall decrease in waste volume, if not the chemical tailoring of this volume to be more amenable to these disposal methods. There must be a tradeoff in overall costs, technology development costs, treatment and disposal costs. But in general, if separations can be carried to a more developed level, the volume reductions will give cost gains which will support the effort. As technology is developed, the flow charts set up for dealing with the different waste streams will be narrowed by decisions made at different points. Adequate scientific support for these decisions will result in the minimum costs in developing eventual waste processing streams

  19. Sensorineural hearing loss in children.

    LENUS (Irish Health Repository)

    Wormald, R

    2010-02-01

    The objective of the study was to examine the aetiology of sensorineural hearing loss (SNHL) in a paediatric population presenting to the National Centre of Medical Genetics. A retrospective chart review from 1998 to 2006. One hundred and twenty nine children were investigated for SNHL. The average age of diagnosis of hearing loss was 36 months. The degree of hearing loss was mild in 8 children, moderate in 33 children, severe in 31 children and profound in 57 children. Eighty-five children (66%) were diagnosed with a hereditary hearing loss, 11 (8%) children had an acquired hearing loss and no cause found in 33 (26%) children. This is the first report of the causes of hearing loss in Irish children. The mean age of diagnosis in our cohort is high and emphasises the need for a neonatal screening programme. There remains a number of children for whom the cause of hearing loss remains unknown.

  20. Reduction of dinitrogen ligands

    International Nuclear Information System (INIS)

    Richards, R.L.

    1983-01-01

    Processes of dinitrogen ligand reduction in complexes of transition metals are considered. The basic character of the dinitrogen ligand is underlined. Data on X-ray photoelectronic spectroscopy and intensities of bands ν (N 2 ) in IR-spectra of nitrogen complexes are given. The mechanism of protonation of an edge dinitrogen ligand is discussed. Model systems and mechanism of nitrogenogenase are compared

  1. Infinitary Combinatory Reduction Systems

    DEFF Research Database (Denmark)

    Ketema, Jeroen; Simonsen, Jakob Grue

    2011-01-01

    We define infinitary Combinatory Reduction Systems (iCRSs), thus providing the first notion of infinitary higher-order rewriting. The systems defined are sufficiently general that ordinary infinitary term rewriting and infinitary ¿-calculus are special cases. Furthermore,we generalise a number...

  2. Galactorrhea after reduction mammaplasty

    NARCIS (Netherlands)

    Schuurman, A. H.; Assies, J.; van der Horst, C. M.; Bos, K. E.

    1993-01-01

    A case of extremely painful swelling of the breasts following a reduction mammaplasty is presented. There were no signs of an abscess or hematoma. A milky white fluid due to galactorrhea was evacuated at operation, and further galactorrhea was inhibited by medication. The pathogenesis of

  3. (MTT) dye reduction assay.

    African Journals Online (AJOL)

    to inhibit proliferation of HeLa cells was determined using the 3443- dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) dye reduction assay. Extracts from roots of Agathisanthemum bojeri, Synaptolepis kirkii and Zanha africana and the leaf extract of Physalis peruviana at a concentration of 10 pg/ml inhibited cell ...

  4. Streaming Reduction Circuit

    NARCIS (Netherlands)

    Gerards, Marco Egbertus Theodorus; Kuper, Jan; Kokkeler, Andre B.J.; Molenkamp, Egbert

    2009-01-01

    Reduction circuits are used to reduce rows of floating point values to single values. Binary floating point operators often have deep pipelines, which may cause hazards when many consecutive rows have to be reduced. We present an algorithm by which any number of consecutive rows of arbitrary lengths

  5. [Hearing loss and idoneity--the segnalation of noise-induced hearing loss hearing Loss].

    Science.gov (United States)

    Albera, Roberto; Dagna, Federico; Cassandro, Claudia; Canale, Andrea

    2011-01-01

    Work idoneity in hearing loss must be related to working ability and evolution risks. Working ability is referred to the difficulties found in speech comprehension and in signals perception. As regards hearing loss evolution it is necessary to define if the subject is affected by conductive or neurosensorial hearing loss. In conductive hearing loss it is necessary to evaluate entity and frequential distribution of the deficit. In neurosensorial hearing loss it is necessary to distinguish between noise-induced hearing loss and extraprofessional hearing loss. In noise-induced hearing loss the evolution risk is high if the noise exposure is less than 10-15 years or the actual noise exposure is louder than the former. In case of extraprofessional hearing loss the evolution risk is higher in presbycusis, endolymphatic hydrops and toxic hearing loss. The necessity to report the presence on professionale noise-induced hearing loss arises if audiometric threshold is more than 25 dB at 0.5-1-2-3-4 kHz and if it is verified the professional origine of hearing loss.

  6. Rewarding reductions, realizing results. Legal options for making compensated reduction a reality

    Energy Technology Data Exchange (ETDEWEB)

    Petsonk, A. [Environmental Defense, Washington DC (United States)

    2005-07-01

    The concept of 'Compensated Reduction' (CR) offers a potentially crucial set of incentives for reducing greenhouse gas (GHG) emissions from tropical deforestation. It is urgent that these incentives begin to flow as soon as possible - urgent from the perspective of limiting emissions and stabilizing GHG concentrations at a level, and in a time frame, that would avert dangerous irreversible climate change. It is urgent from the perspective of saving the world's dwindling rainforest biodiversity. And it is urgent from the social perspective of the communities that live in - and depend on - the world's rainforests. But from a legal perspective, what options are available for bringing the Compensated Reduction framework forward immediately, not only to spur capacity-building in tropical forest nations, but also to ensure that it begins to deliver, as soon as possible, real financial incentives for keeping forests standing? This chapter explores four legal options, namely, (1) allowing tropical forest nations to participate in Kyoto by joining Annex B of the Protocol; (2) amending the Marrakesh Rules to broaden the Clean Development Mechanism so that it embraces CR; (3) adopting a 'stand-alone' agreement; and (4) providing 'guaranteed carbon market access'. Under this last, hitherto unexplored option, the UNFCCC COP would take an early decision guaranteeing that developing nations that, between now and 2012, successfully reduce national rates of deforestation below a historical baseline, would receive tradable carbon credits that are fully fungible in the global carbon market after 2012. The chapter concludes by recommending that nations explore Option (4) in greater depth.

  7. Constructing a holistic approach to disaster risk reduction: the significance of focusing on vulnerability reduction.

    Science.gov (United States)

    Palliyaguru, Roshani; Amaratunga, Dilanthi; Baldry, David

    2014-01-01

    As a result of the increase in natural disaster losses, policy-makers, practitioners, and members of the research community around the world are seeking effective and efficient means of overcoming or minimising them. Although various theoretical constructs are beneficial to understanding the disaster phenomenon and the means of minimising losses, the disaster risk management process becomes less effective if theory and practice are set apart from one another. Consequently, this paper seeks to establish a relationship between two theoretical constructs, 'disaster risk reduction (DRR)' and 'vulnerability reduction', and to develop a holistic approach to DRR with particular reference to improving its applicability in practical settings. It is based on a literature review and on an overall understanding gained through two case studies of post-disaster infrastructure reconstruction projects in Sri Lanka and three expert interviews in Sri Lanka and the United Kingdom. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

  8. Gains or Losses of Ultratrace Elements in Polyethylene Containers

    DEFF Research Database (Denmark)

    Heydorn, Kaj; Damsgaard, Else

    1982-01-01

    The extent of elimination of losses and reduction of blank values in ultratrace elemental analysis can only be ascertained by comprehensive investigations for each element separately. Different, and partially conflicting precautions are found to be needed in the determination of manganese, copper......, selenium, and mercury by neutron-activation analysis when polyethylene irradiation containers are used....

  9. Transformative Learning Following Job Loss: A Dissertation Renewal

    Science.gov (United States)

    Benway, Robert

    2017-01-01

    This study renews a doctoral dissertation written in 2003 on transformative learning following job loss. An abbreviated literature review compares corporate and worker circumstances from the original study to the present time. Findings show that corporations choose reductions in force due to pressure from investors instead of productivity, and…

  10. Histological observations in the Hawaiian reef coral, Porites compressa, affected by Porites bleaching with tissue loss

    Science.gov (United States)

    Sudek, M.; Work, Thierry M.; Aeby, G.S.; Davy, S.K.

    2012-01-01

    The scleractinian finger coral Porites compressa is affected by the coral disease Porites bleaching with tissue loss (PBTL). This disease initially manifests as bleaching of the coenenchyme (tissue between polyps) while the polyps remain brown with eventual tissue loss and subsequent algal overgrowth of the bare skeleton. Histopathological investigation showed a loss of symbiont and melanin-containing granular cells which was more pronounced in the coenenchyme than the polyps. Cell counts confirmed a 65% reduction in symbiont density. Tissue loss was due to tissue fragmentation and necrosis in affected areas. In addition, a reduction in putative bacterial aggregate densities was found in diseased samples but no potential pathogens were observed.

  11. The urban perspectives of acid rain

    International Nuclear Information System (INIS)

    Tonn, B.E.

    1993-01-01

    This report documents discussions held during a workshop an Urban Perspective of Acid Rain. The workshop was sponsored by the Office of the Director, National Acid Precipitation Assessment Program (NAPAP). NAPAP anticipates giving increased emphasis to the benefits in urban areas of emissions reductions. The goal of this informal, exploratory workshop was to serve as a first step towards identifying pollutant monitoring, and research and assessment needs to help answer, from an urban perspective, the two key questions posed to NAPAP by Congress: (1) what are the costs, benefits, and effectiveness of the acid rain control program, and (2) what reductions in deposition, rates are needed in order to prevent adverse effects? The workshop addressed research activities needed to respond to these questions. The discussions focused. sequentially, on data needs, data and model availability, and data and modeling gaps. The discussions concentrated on four areas of effects: human health, materials, urban forests, and visibility

  12. Female pattern alopecia: current perspectives

    Science.gov (United States)

    Levy, Lauren L; Emer, Jason J

    2013-01-01

    Hair loss is a commonly encountered problem in clinical practice, with men presenting with a distinctive pattern involving hairline recession and vertex balding (Norwood-Hamilton classification) and women exhibiting diffuse hair thinning over the crown (increased part width) and sparing of the frontal hairline (Ludwig classification). Female pattern hair loss has a strikingly overwhelming psychological effect; thus, successful treatments are necessary. Difficulty lies in successful treatment interventions, as only two medications – minoxidil and finasteride – are approved for the treatment of androgenetic alopecia, and these medications offer mediocre results, lack of a permanent cure, and potential complications. Hair transplantation is the only current successful permanent option, and it requires surgical procedures. Several other medical options, such as antiandrogens (eg, spironolactone, oral contraceptives, cyproterone, flutamide, dutasteride), prostaglandin analogs (eg, bimatoprost, latanoprost), and ketoconazole are reported to be beneficial. Laser and light therapies have also become popular despite the lack of a profound benefit. Management of expectations is crucial, and the aim of therapy, given the current therapeutic options, is to slow or stop disease progression with contentment despite patient expectations of permanent hair regrowth. This article reviews current perspectives on therapeutic options for female pattern hair loss. PMID:24039457

  13. The role of carbohydrate in dietary prescription for weight loss

    DEFF Research Database (Denmark)

    Astrup, Arne

    content of ad libitum diets produces weight loss in both the short-term and over periods as long as 7 years. A fat-reduced diet, combined with physical activity, reduces all risk factors for cardiovascular disease, and reduces the incidence of type 2 diabetes. The combination of reduction of dietary fat...... and energy, and increased physical activity, has been shown to reduce the incidence of diabetes by 58% in two major trials. In post hoc analyses the reduction in dietary fat (energy density) and increase in fibre were the strongest predictors of weight loss and diabetes protective effects. It remains...... to be shown whether a low-glycemic index diet provides benefits beyond this. Low-carbohydrate diets may be an option for inducing weight loss in obese patients, but a very low intake of carbohydrate-rich foods is not commensurate with a healthy and palatable diet in the long term. However, there is evidence...

  14. Low ac loss geometries in YBCO coated conductors and impact on conductor stability

    Energy Technology Data Exchange (ETDEWEB)

    Duckworth, Robert C [ORNL; List III, Frederick Alyious [ORNL; Paranthaman, Mariappan Parans [ORNL; Rupich, M. W. [American Superconductor Corporation, Westborough, MA; Zhang, W. [American Superconductor Corporation, Westborough, MA; Xie, Y. Y. [SuperPower Incorporated, Schenectady, New York; Selvamanickam, V. [SuperPower Incorporated, Schenectady, New York

    2007-01-01

    Reduction of ac losses in applied ac fields can be accomplished through either the creation of filaments and bridging in YBCO coated conductors or an assembly of narrow width YBCO tapes. The ac losses for each of these geometries were measured at 77 K in perpendicular ac fields up to 100 mT. While ac loss reduction was achieved with YBCO filaments created through laser scribing and inkjet deposition, the assembly of stacked YBCO conductor provides an alternative method of ac loss reduction. When compared to a 4-mm wide YBCO coated conductor with a critical current of 60 A, the ac loss in a stack of 2-mm wide YBCO coated conductors with a similar total critical current was reduced. While the reduction in ac loss in a 2-mm wide stack coincided with the reduction in the engineering current density of the conductor, further reduction of ac loss was obtained through the splicing of the 2-mm wide tapes with low resistance solders. To better determine the practicality of these methods from a stability point of view, a numerical analysis was carried out to determine the influence of bridging and splicing on stability of a YBCO coated conductor for both liquid nitrogen-cooled and conduction cooled geometries.

  15. Economic decision biases and fundamental motivations: how mating and self-protection alter loss aversion.

    Science.gov (United States)

    Li, Yexin Jessica; Kenrick, Douglas T; Griskevicius, Vladas; Neuberg, Steven L

    2012-03-01

    Much research shows that people are loss averse, meaning that they weigh losses more heavily than gains. Drawing on an evolutionary perspective, we propose that although loss aversion might have been adaptive for solving challenges in the domain of self-protection, this may not be true for men in the domain of mating. Three experiments examine how loss aversion is influenced by mating and self-protection motives. Findings reveal that mating motives selectively erased loss aversion in men. In contrast, self-protective motives led both men and women to become more loss averse. Overall, loss aversion appears to be sensitive to evolutionarily important motives, suggesting that it may be a domain-specific bias operating according to an adaptive logic of recurring threats and opportunities in different evolutionary domains.

  16. How Working Time Reduction Affects Employment and Earnings

    OpenAIRE

    Santos Raposo, P.M.; van Ours, J.C.

    2008-01-01

    December 1, 1996 Portugal introduced a new law on working hours which gradually reduced the standard workweek from 44 hours to 40 hours. We study how this mandatory working hours reduction affected employment and earnings of workers involved. We find for workers who were affected by the new law that working hours decreased, while hourly wages increased, keeping monthly earnings approximately constant. We also find that the working hours reduction did not lead to an increased job loss of worke...

  17. User perspectives in public transport timetable optimisation

    DEFF Research Database (Denmark)

    Jensen, Jens Parbo; Nielsen, Otto Anker; Prato, Carlo Giacomo

    2014-01-01

    The present paper deals with timetable optimisation from the perspective of minimising the waiting time experienced by passengers when transferring either to or from a bus. Due to its inherent complexity, this bi-level minimisation problem is extremely difficult to solve mathematically, since tim...... on the large-scale public transport network in Denmark. The timetable optimisation approach yielded a yearly reduction in weighted waiting time equivalent to approximately 45 million Danish kroner (9 million USD)....

  18. The Unsustainable Trend of Natural Hazard Losses in the United States

    Directory of Open Access Journals (Sweden)

    Melanie Gall

    2011-11-01

    Full Text Available In the United States, direct losses from natural hazards are on the rise with hurricanes, flooding, and severe storms contributing about three quarters of the total damages. While losses from severe storms have been stable over the past fifty years, hurricane and flood losses have tripled. Per capita losses are also increasing showing that impacts outpace population growth with high per capita losses occurring largely in the Southeast and Midwest. If the loss escalation of the past two decades continues into the future, then direct losses of $300 to $400 billion within a single decade are possible. In order to reverse this trend, sustainable development, vulnerability reduction, and hazard mitigation must become priorities and current loss reduction efforts need to be evaluated and re-assessed in terms of their effectiveness. These conclusions are drawn from the analysis of spatial and temporal trends in direct losses from natural hazards using SHELDUSTM data from 1960 through 2009. Loss data are adjusted for inflation, population, and wealth to capture both trends in total losses and per capita losses. The loss data are then compared to disaster-related federal government and private insurance expenditures.

  19. Loss reduction in industrial motor systems: the structure of the Brazilian program structure focusing the autosustainability (optimization of industrial motor systems); Reducao de perdas em sistemas motrizes industriais: a estrutura do programa brasileiro com foco na autosustentabilidade (otimizacao de sistemas motrizes industriais)

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Vanda Alves dos; Soares, George Alves; Perrone, Fernando Pinto Dias; Ferreira, Carlos Aparecido; Oliveira, Humberto Luiz de; Motta, Braulio Romano; Silva, Humberto Reis Braga da [ELETROBRAS, Rio de Janeiro, RJ (Brazil). Dept. de Desenvolvimento de Projetos Especiais. Div. de Projetos Setoriais de Eficiencia Energetica]. E-mails: vandaas@eletrobras.com; georgesoares@eletrobras.com; carlosaparecido@eletrobras.com; humberto.oliveira@eletrobras.com; brauliorm@eletrobras.com; hhbraga@eletrobras.com

    2006-07-01

    This paper presents the achievements and goals of the Industrial Motor System Optimization Project as developed by the PROCEL INDUSTRIA -Brazilian Energy Efficiency Industrial Program, within the scope of PROCEL - National Program for Electric Power Conservation, carried out ELETROBRAS since 1985. Its main objective is to minimize losses in the motor driven systems already installed in the Brazilian industry. In order to implement this program, ELETROBRAS is continuous making agreements with the state industry federations aiming to develop mechanisms and to manage energy efficiency implementation projects looking forward its self supporting. PROCEL INDUSTRIA aims to reduce the waste of electric energy in the industrial sector, to increase the industries competition, by reducing their costs and to contribute to the preservation and cleanness of environment. (author)

  20. Spontaneous wave packet reduction

    International Nuclear Information System (INIS)

    Ghirardi, G.C.

    1994-06-01

    There are taken into account the main conceptual difficulties met by standard quantum mechanics in dealing with physical processes involving macroscopic system. It is stressed how J.A.Wheeler's remarks and lucid analysis have been relevant to pinpoint and to bring to its extreme consequences the puzzling aspects of quantum phenomena. It is shown how the recently proposed models of spontaneous dynamical reduction represent a consistent way to overcome the conceptual difficulties of the standard theory. Obviously, many nontrivial problems remain open, the first and more relevant one being that of generalizing the model theories considered to the relativistic case. This is the challenge of the dynamical reduction program. 43 refs, 2 figs