WorldWideScience

Sample records for locos technology simulation

  1. Is there LOCOS after LOCOS?

    Science.gov (United States)

    Deleonibus, S.

    1997-07-01

    Decreasing the field oxide thickness, increasing the temperature or oxidation pressure in a LOCOS type isolation improves field oxide thinning. Under the above regimes, the bird's beak growth results from a reaction-limited mechanism during the linear part of the oxidation process. The latter property is of major importance for the future shrink of LOCOS isolation towards sub-0.1 μm CMOS designs. Market pressure, because of the strong demand for low-voltage and low-power ULSI devices, is defining the framework. Matching the trend in depth-of-focus reduction in lithography tools and limiting process complexity will have to be weighed constantly. The reduction of isolation dimension losses to zero is not as urgent as it used to be. Shallow trench isolation has not come to maturity because of the technically difficult and economically practicable trade-off to be found between planarization and device leakage. Refilling and planarization process standards have not yet been established despite the major progress made in chemical mechanical polishing. The contradiction betwen the planarization issue and the need for an abrupt step at the isolation/active-area edge in order to avoid subthreshold leakage of the MOS active sidewalls still has to be solved. After a brief historical review, we point out and reconsider the main advantages and drawbacks of LOCOS type and shallow trench isolation processes. Within that framework, the impact of isolation design rules on device integration density and isolation performance is reviewed and commented on.

  2. Matlab Based LOCO

    Energy Technology Data Exchange (ETDEWEB)

    Portmann, Greg; /LBL, Berkeley; Safranek, James; Huang, Xiaobiao; /SLAC

    2011-10-18

    The LOCO algorithm has been used by many accelerators around the world. Although the uses for LOCO vary, the most common use has been to find calibration errors and correct the optics functions. The light source community in particular has made extensive use of the LOCO algorithms to tightly control the beta function and coupling. Maintaining high quality beam parameters requires constant attention so a relatively large effort was put into software development for the LOCO application. The LOCO code was originally written in FORTRAN. This code worked fine but it was somewhat awkward to use. For instance, the FORTRAN code itself did not calculate the model response matrix. It required a separate modeling code such as MAD to calculate the model matrix then one manually loads the data into the LOCO code. As the number of people interested in LOCO grew, it required making it easier to use. The decision to port LOCO to Matlab was relatively easy. It's best to use a matrix programming language with good graphics capability; Matlab was also being used for high level machine control; and the accelerator modeling code AT, [5], was already developed for Matlab. Since LOCO requires collecting and processing a relative large amount of data, it is very helpful to have the LOCO code compatible with the high level machine control, [3]. A number of new features were added while porting the code from FORTRAN and new methods continue to evolve, [7][9]. Although Matlab LOCO was written with AT as the underlying tracking code, a mechanism to connect to other modeling codes has been provided.

  3. In Loco Parentis Indulgentis?

    Science.gov (United States)

    Pitts, James H.

    1980-01-01

    Examines significant aspects of student personnel work vis a vis student development. Reveals that "in loco parentis" has been a manifestation of a more overarching philosophical belief that colleges should foster the development of the whole student. (Author)

  4. In Loco Parentis Revisited?

    Science.gov (United States)

    Morrill, Richard L.; And Others

    1986-01-01

    Two perspectives are presented on some of the questions raised as the doctrine of the college 'in loco parentis' re-emerges as a campus issue, including student, parent, and institutional expectations. (MSE)

  5. Research on the Technology of Planarization for LOCOS Process%应用于LOCOS隔离工艺的平坦化技术研究

    Institute of Scientific and Technical Information of China (English)

    高渊; 刘英坤; 邓建国; 梁东升; 董军平

    2012-01-01

    The mechanism of LOCOS process was introduced, and the technology of etch-back for LOCOS was researched. Smooth surface was obtained by adjusting the gas flow rate. The flow rate of CHF3 was 50 mL/min, and the flow rate of O2 was 2 mL/min. The CMP technology for LOCOS process was studied. Polishing rate and precision were controlled by optimizing the parameters of pressure, rotation and slurry, etc. The coherence of planarization is improved and good surface state is attained under the condition that the pressure is 1 psi, the rotation is 25 r/min, and the slurry is 120 mL/min. Compared with the etch-back, the effect of CMP is better. The CMP technology is applied for the production.%介绍了LOCOS隔离技术的原理,研究了应用于LOCOS工艺的反刻平坦化技术,通过调整刻蚀中反应气体流量等工艺参数,在CHF3流量50 mL/min、O2流量2 mL/min条件下,获得了较好的平坦化表面.研究了应用于LOCOS工艺的CMP平坦化技术,通过调整CMP压力、转速、流量等工艺参数,控制了抛光速率和精度,提高平坦化的均匀性,在工艺条件为压力1 psi(1 psi=6.89×103 Pa),转速25 r/min,流量120 mL/min时,获得了良好的平坦化形貌.通过实验对比发现,CMP平坦化效果优于反刻平坦化,适合于实际生产应用.

  6. Loco signaling pathway in longevity.

    Science.gov (United States)

    Lin, Yuh-Ru; Parikh, Hardik; Park, Yongkyu

    2011-05-01

    Despite the various roles of regulator of G protein signaling (RGS) protein in the G protein signaling pathway that have been defined, the function of RGS has not been characterized in longevity signaling pathways. We found that reduced expression of Loco, a Drosophila RGS protein, resulted in a longer lifespan of flies with stronger resistance to stress, higher MnSOD activity and increased fat content. In contrast, overexpression of the loco gene shortened the fly lifespan significantly, lowered stress resistance and reduced fat content, also indicating that the RGS domain containing GTPase-activating protein (GAP) activity is related to the regulation of longevity. Interestingly, expressional changes of yeast RGS2 and rat RGS14, homologs to the fly Loco, also affected oxidative stress resistance and longevity in the respective species. It is known that Loco inactivates inhibitory Gαi•GTP protein to reduce activity of adenylate cyclase (AC) and RGS14 interacts with activated H-Ras and Raf-1 kinases, which subsequently inhibits ERK phosphorylation. We propose that Loco/RGS14 protein may regulate stress resistance and longevity as an activator in AC-cAMP-PKA pathway and/or as a molecular scaffold that sequesters active Ras and Raf from Ras•GTP-Raf-MEK-ERK signaling pathway. Consistently, our data showed that downregulation of Loco significantly diminishes cAMP amounts and increases p-ERK levels with higher resistance to the oxidative stress.

  7. Changes in the loco-regional cerebral blood flow (r.C.B.F.) during a simulation of weightlessness

    Science.gov (United States)

    Guell, A.; Dupui, Ph.; Barrere, M.; Fanjaud, G.; Bes, A.; Kotowskaia, A.

    Experiments of prolonged bedrest in antiorthostatic position are conducted in order to simulate cardio-circulatory modifications observed in weightlessness. Until now, no studies of r.C.B.F. have been effected in these conditions. Six young, healthy volunteers (average age 23.8) were placed in strict bedrest and in antiorthostatic position -4° for 7 days. The r.C.B.F. measurements were studied by 133Xe inhalation method using a 32 detectors system. Studies were made first in basal conditions, then between the 6th and 12th hr, and finally between the 72nd and the 78th hr after the beginning of the experiment. Three of the subjects received 0.450 mg of Clonidine daily during the experiment. In the subjects having taken no Clonidine, we observed a constant increase in r.C.B.F. (12, 17 and 16% respectively) in the first 12 hr; at the 72nd hour, all values had returned to basal state. This findings agrees with the well known notion of a rapid correction of hemodynamic disturbances observed in the first days of weightlessness. In the subjects treated with Clonidine, the increase of r.C.B.F. did not occur. Several mechanicsms of action are possible; the Clonidine affecting either the heart by inhibiting volemic atrial receptors, or the brain by direct vasoconstriction.

  8. The Lunar Occultation Observer (LOCO) mission concept

    Science.gov (United States)

    Miller, Richard S.

    2007-09-01

    The hard X-ray sky has tremendous potential for future discoveries and is one of the last electromagnetic regimes without a sensitive all-sky survey. A new approach to such a survey is to utilize the Moon as an occulting disk. The Lunar Occultation Observer (LOCO) mission concept, based on this Lunar Occultation Technique (LOT) and incorporating advanced inorganic scintillators as a detection medium, represents a sensitive and cost effective option for NASA's Beyond Einstein Black Hole Finder Probe or a future Explorer-class mission. We present the motivating factors for the LOT, outline developmental details and simulation results, as well as give preliminary estimates for source detection sensitivity.

  9. El loco y el idiota.

    OpenAIRE

    Alfredo Fierro Bardají

    1982-01-01

    El loco y el idiota -denominados así, según el uso cotidiano y vulgar, inmisericordemente despectivo -sin duda alguna son las dos figuras paradigmáticas de enajenación de la razón, el uno por desarreglo, el otro por defecto. El loco es el trastornado en su razón, el que se ha hecho un desbarajuste con un poder anímico esencialmente orientado a crear orden, a producir ideas claras y distintas. El idiota es el deficiente en su razón, el que participa de ella en medida tan escasa que se queda en...

  10. The New In Loco Parentis.

    Science.gov (United States)

    Thomas, Nancy L.

    1991-01-01

    Traditionally, colleges have had right to act in place of student's parents and duty to protect his safety, morals, and welfare. Dramatic changes in this approach occurred after World War II including rejection of the loco parentis role by courts, but trend is away from freedom and flexibility of 1960s as illustrated by policy changes at Boston…

  11. Is "In Loco Parentis" Dead?

    Science.gov (United States)

    Zirkel, Perry A.; Reichner, Henry F.

    1987-01-01

    The concept "in loco parentis" is discussed in relation to its historical place in education and its current status. The doctrine has expanded from its original idea of "restraint and correction" to figure significantly in court cases involving corporal punishment, student searches, school rules, correlative duties, and…

  12. El loco y el idiota.

    Directory of Open Access Journals (Sweden)

    Alfredo Fierro Bardají

    1982-01-01

    Full Text Available El loco y el idiota -denominados así, según el uso cotidiano y vulgar, inmisericordemente despectivo -sin duda alguna son las dos figuras paradigmáticas de enajenación de la razón, el uno por desarreglo, el otro por defecto. El loco es el trastornado en su razón, el que se ha hecho un desbarajuste con un poder anímico esencialmente orientado a crear orden, a producir ideas claras y distintas. El idiota es el deficiente en su razón, el que participa de ella en medida tan escasa que se queda en un grado subhumano, a la altura de los brutos animales. La razón -una cierta determinación ideológica y práctica de la razón -crea al idiota y al loco como necesarios antagonistas para poder desarrollar su aventura histórica. Relegados a los rincones de la escena donde la razón occidental moderna despliega sus hazañas, en ningún modo son personajes secundarios de la historia. En su penumbra y su mutismo revelan sobre la razón secretos que ésta, en toda su cartesiana autoconciencia, nunca quiso ni pudo vislumbrar.

  13. Rehearsal Enabling Simulation Technologies

    Science.gov (United States)

    2011-03-01

    developed by Renaissance Sciences Corporation (RSC) in collaboration with Elmendorf Civil Engineering, Joint Pacific Area Range Complex (JPARC) management...from the Air Force Combat Climatology Center (AFCCC) into Expert Common Immersive Theatre Environment (XCITE) threat simulations. AFCCC created an...L-3 Communications Link Simulation and Training, and Renaissance Science Corporation. The team provided as needed consultation to numerous

  14. BEST: Biochemical Engineering Simulation Technology

    Energy Technology Data Exchange (ETDEWEB)

    1996-01-01

    The idea of developing a process simulator that can describe biochemical engineering (a relatively new technology area) was formulated at the National Renewable Energy Laboratory (NREL) during the late 1980s. The initial plan was to build a consortium of industrial and U.S. Department of Energy (DOE) partners to enhance a commercial simulator with biochemical unit operations. DOE supported this effort; however, before the consortium was established, the process simulator industry changed considerably. Work on the first phase of implementing various fermentation reactors into the chemical process simulator, ASPEN/SP-BEST, is complete. This report will focus on those developments. Simulation Sciences, Inc. (SimSci) no longer supports ASPEN/SP, and Aspen Technology, Inc. (AspenTech) has developed an add-on to its ASPEN PLUS (also called BioProcess Simulator [BPS]). This report will also explain the similarities and differences between BEST and BPS. ASPEN, developed by the Massachusetts Institute of Technology for DOE in the late 1970s, is still the state-of-the-art chemical process simulator. It was selected as the only simulator with the potential to be easily expanded into the biochemical area. ASPEN/SP, commercially sold by SimSci, was selected for the BEST work. SimSci completed work on batch, fed-batch, and continuous fermentation reactors in 1993, just as it announced it would no longer commercially support the complete ASPEN/SP product. BEST was left without a basic support program. Luckily, during this same time frame, AspenTech was developing a biochemical simulator with its version of ASPEN (ASPEN PLUS), which incorporates most BEST concepts. The future of BEST will involve developing physical property data and models appropriate to biochemical systems that are necessary for good biochemical process design.

  15. Simulation and New Learning Technologies.

    Science.gov (United States)

    Issenberg, S. Barry; Gordon, Michael S.; Gordon, David Lee; Safford, Robert E.; Hart, Ian R.

    2001-01-01

    In the future, virtual reality technology based initially on data from Visible Human Data sets will provide the majority of simulation-based training. Indicates that evidence-based outcomes must show these systems to be effective instruments for teaching and assessment, and medical educators must be willing to effect change in medical education to…

  16. A novel approach in automatic estimation of rats' loco-motor activity

    Science.gov (United States)

    Anishchenko, Lesya N.; Ivashov, Sergey I.; Vasiliev, Igor A.

    2014-05-01

    The paper contains feasibility study of a method for bioradar monitoring of small laboratory animals loco-motor activity improved by using a corner reflector. It presents results of mathematical simulation of bioradar signal reflection from the animal with the help of finite-difference time-domain method. It was proved both by theoretical and experimental results that a corner reflector usage during monitoring of small laboratory animals loco-motor activity improved the effectiveness of the method by reducing the dependency of the power flux density level from the distance between antennas block and the object.

  17. Is the "In Loco Parentis" Doctrine Dead?

    Science.gov (United States)

    Zirkel, Perry A.; Reichner, Henry F.

    1986-01-01

    Reviews history of the doctrine of "in loco parentis." Examines court opinions in which the doctrine has surfaced as an issue in the following areas of litigation: corporal punishment, student searches, school rules, correlative duties, and teacher-student relationship at the college level. Finds that the status and scope of the doctrine…

  18. Current Trends in Higher Education Technology: Simulation

    Science.gov (United States)

    Damewood, Andrea M.

    2016-01-01

    This paper is focused on how technology in use changes over time, and the current trend of simulation technology as a supported classroom technology. Simulation-based training as a learning tool is discussed within the context of adult learning theories, as is the technology used and how today's higher education technology administrators support…

  19. Development and Applications of Simulation Technology

    Institute of Scientific and Technical Information of China (English)

    WangZicai

    2004-01-01

    The developing process of simulation technology is discussed in view of its development, maturation and further development.The applications of simulation technology in the fields of national economy are introduced. Finally, the level and status quo of simulation technology home and overseas are analyzed, and its future trend in the new century is presented.

  20. Is "In Consortio Cum Parentibus" the New "In Loco Parentis?"

    Science.gov (United States)

    Henning, Gavin

    2007-01-01

    "In loco parentis" had been the philosophical foundation of higher education policy and practice since 1913 when it was established as a legal doctrine in Gott v. Berea. The doctrine defined the relationship between colleges, students, and parents. That relationship has changed with the death of "in loco parentis" in Dixon v. Alabama Board of…

  1. Simulation and Modeling Methodologies, Technologies and Applications

    CERN Document Server

    Filipe, Joaquim; Kacprzyk, Janusz; Pina, Nuno

    2014-01-01

    This book includes extended and revised versions of a set of selected papers from the 2012 International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2012) which was sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC) and held in Rome, Italy. SIMULTECH 2012 was technically co-sponsored by the Society for Modeling & Simulation International (SCS), GDR I3, Lionphant Simulation, Simulation Team and IFIP and held in cooperation with AIS Special Interest Group of Modeling and Simulation (AIS SIGMAS) and the Movimento Italiano Modellazione e Simulazione (MIMOS).

  2. Influence of Biological Factors on Connectivity Patterns for Concholepas concholepas (loco) in Chile.

    Science.gov (United States)

    Garavelli, Lysel; Colas, François; Verley, Philippe; Kaplan, David Michael; Yannicelli, Beatriz; Lett, Christophe

    2016-01-01

    In marine benthic ecosystems, larval connectivity is a major process influencing the maintenance and distribution of invertebrate populations. Larval connectivity is a complex process to study as it is determined by several interacting factors. Here we use an individual-based, biophysical model, to disentangle the effects of such factors, namely larval vertical migration, larval growth, larval mortality, adults fecundity, and habitat availability, for the marine gastropod Concholepas concholepas (loco) in Chile. Lower transport success and higher dispersal distances are observed including larval vertical migration in the model. We find an overall decrease in larval transport success to settlement areas from northern to southern Chile. This spatial gradient results from the combination of current direction and intensity, seawater temperature, and available habitat. From our simulated connectivity patterns we then identify subpopulations of loco along the Chilean coast, which could serve as a basis for spatial management of this resource in the future.

  3. Calibrating transport lines using LOCO techniques

    Energy Technology Data Exchange (ETDEWEB)

    Yves Roblin

    2011-09-01

    With the 12GeV upgrade underway at CEBAF, there is a need to re-characterize the beamlines after the modifications made to it to accommodate running at higher energies. We present a linear perturbation approach to calibrating the optics model of transport lines. This method is adapted from the LOCO method in use for storage rings. We consider the effect of quadrupole errors, dipole construction errors as well as beam position monitors and correctors calibrations. The ideal model is expanded to first order in Taylor series of the quadrupole errors. A set of difference orbits obtained by exciting the correctors along the beamline is taken, yielding the measured response matrix. An iterative procedure is invoked and the quadrupole errors as well as beam position monitors and corrector calibration factors are obtained. Here we present details of the method and results of first measurements at CEBAF in early 2011.

  4. Novel Simulated moving bed technologies

    Energy Technology Data Exchange (ETDEWEB)

    Purdue University

    2003-12-30

    Cellulose and hemicellulose from plants and other biomass can be hydrolyzed to produce sugars (i.e. glucose and xylose). Once these sugars are separated from other impurities, they can serve as feedstock in fermentation to produce ethanol (as fuels), lactic acid, or other valuable chemicals. The need for producing fuels and chemicals from renewable biomass has become abundantly clear over the last decade. However, the cost of producing fermentable sugars from biomass hydrolyzate using existing technology is relatively high and has been a major obstacle. The objective of this project is to develop an efficient and economical simulated moving bed (SMB) process to recover fermentable sugars from biomass hydrolyzate. Sulfuric acid can hydrolyze the cellulose and hemicellulose in biomass to sugars, but this process can generate byproducts such as acetic acid, and can lead to further degradation of the xylose to furfural and glucose to hydroxymethyl furfural (HMF). Also, lignin and other compounds in the biomass will degrade to various phenolic compounds. If the concentrations of these compounds exceed certain threshold levels, they will be toxic to the downstream fermentation, and will severely limit the usefulness of the derived sugars. Standard post-hydrolysis processing involves neutralization of sulfuric acid, usually with lime (calcium hydroxide). A study by Wooley et al.showed that the limed hydrolyzate gave a low ethanol yield in fermentation test (20% of theoretical yield compared to 77% of theoretical yield from fermentation of pure sugars). They showed that instead of adding lime, an ion exclusion chromatography process could be used to remove acids, as well as to isolate the sugars from the biomass hydrolyzate. In this project, we investigated the feasibility of developing an economical SMB process based on (1) a polymeric adsorbent, Dowex99, which was used by Wooley et al., (2) a second polymeric adsorbent, poly-4-vinyl pyridine (or PVP in short, Reilly

  5. Novel Simulated moving bed technologies

    Energy Technology Data Exchange (ETDEWEB)

    Purdue University

    2003-12-30

    Cellulose and hemicellulose from plants and other biomass can be hydrolyzed to produce sugars (i.e. glucose and xylose). Once these sugars are separated from other impurities, they can serve as feedstock in fermentation to produce ethanol (as fuels), lactic acid, or other valuable chemicals. The need for producing fuels and chemicals from renewable biomass has become abundantly clear over the last decade. However, the cost of producing fermentable sugars from biomass hydrolyzate using existing technology is relatively high and has been a major obstacle. The objective of this project is to develop an efficient and economical simulated moving bed (SMB) process to recover fermentable sugars from biomass hydrolyzate. Sulfuric acid can hydrolyze the cellulose and hemicellulose in biomass to sugars, but this process can generate byproducts such as acetic acid, and can lead to further degradation of the xylose to furfural and glucose to hydroxymethyl furfural (HMF). Also, lignin and other compounds in the biomass will degrade to various phenolic compounds. If the concentrations of these compounds exceed certain threshold levels, they will be toxic to the downstream fermentation, and will severely limit the usefulness of the derived sugars. Standard post-hydrolysis processing involves neutralization of sulfuric acid, usually with lime (calcium hydroxide). A study by Wooley et al.showed that the limed hydrolyzate gave a low ethanol yield in fermentation test (20% of theoretical yield compared to 77% of theoretical yield from fermentation of pure sugars). They showed that instead of adding lime, an ion exclusion chromatography process could be used to remove acids, as well as to isolate the sugars from the biomass hydrolyzate. In this project, we investigated the feasibility of developing an economical SMB process based on (1) a polymeric adsorbent, Dowex99, which was used by Wooley et al., (2) a second polymeric adsorbent, poly-4-vinyl pyridine (or PVP in short, Reilly

  6. Computer simulation technology in inertial confinement (ICF)

    Energy Technology Data Exchange (ETDEWEB)

    Yabe, Takashi (Gunma Univ., Kiryu (Japan). Faculty of Engineering)

    1994-12-01

    Recent development of computational technologies in inertial confinement fusion (ICF) is reviewed with a special emphasis on hydrodynamic simulations. The CIP method developed for ICF simulations is one of the typical examples that are used in various fields of physics such as variety of computational fluid dynamics, astrophysics, laser applications, geophysics, and so on. (author).

  7. Introducing LoCo, a Logic for Configuration Problems

    CERN Document Server

    Aschinger, Markus; Gottlob, Georg; 10.4204/EPTCS.65.4

    2011-01-01

    In this paper we present the core of LoCo, a logic-based high-level representation language for expressing configuration problems. LoCo shall allow to model these problems in an intuitive and declarative way, the dynamic aspects of configuration notwithstanding. Our logic enforces that configurations contain only finitely many components and reasoning can be reduced to the task of model construction.

  8. Introducing LoCo, a Logic for Configuration Problems

    Directory of Open Access Journals (Sweden)

    Markus Aschinger

    2011-08-01

    Full Text Available In this paper we present the core of LoCo, a logic-based high-level representation language for expressing configuration problems. LoCo shall allow to model these problems in an intuitive and declarative way, the dynamic aspects of configuration notwithstanding. Our logic enforces that configurations contain only finitely many components and reasoning can be reduced to the task of model construction.

  9. Game development and simulation with unreal technology

    CERN Document Server

    Tavakkoli, Alireza

    2015-01-01

    Game Development and Simulation with Unreal Technology explores the use of Unreal Engine 4 (UE4) for the development of real-time digital interactive contents to be used in computerized games or simulations. The engine is considered in three main iterations: from the basic use of the engine to build games and simulation content out of the box, to intermediate design of interactive content by building on the pre-supplied contents from the base engine, and through advanced implementations geared toward a comprehensive understanding of the power of the Unreal Engine. This is one of the first book

  10. Interactive simulation of technology management foresight

    DEFF Research Database (Denmark)

    Hansen, Mette Sanne; Rasmussen, Lauge Baungaard; Jacobsen, Peter

    2013-01-01

    Two of the main foresight challenges are how to handle complexity and uncertainty of evolving technology tracks, which may merge and create new challenges for the management of a company in order to avoid sub- optimization. Complexity refers to the difficulty of identifying and quantifying causal...... as a number of intervening stakeholders at different levels of technology management in an organization. Uncertainty comprises lack of knowledge in addition to variable responses of management to identical technological tracks. The purpose of this paper is to identify and reflect on the obstacles...... and possibilities of using the combination of narrative and numerical simulation to explore uncertainties and complexities of technology development and implementation in companies. Foresight as a method to develop technology management strategies can hardly be organized as a separated step by step procedure...

  11. The Lunar Occultation Observer (LOCO) -- A Nuclear Astrophysics All-Sky Survey Mission Concept

    Science.gov (United States)

    Miller, R. S.; Bonamente, M.; Burgess, J. M.; Jenke, P.; Lawrence, D. J.; O'Brien, S.; Orr, M. R.; Paciesas, W. S.; Young, C. A.

    2009-03-01

    The Lunar Occultation Observer (LOCO) is a new γ-ray astrophysics mission concept expected to have unprecedented sensitivity in the nuclear regime. Operating in lunar orbit, LOCO will utilize lunar occultation imaging to survey and probe the cosmos.

  12. Applications of Simulation Technology - Pitfalls and Challenges

    Directory of Open Access Journals (Sweden)

    A.A. Malik

    2015-09-01

    Full Text Available Simulator based training has its own unique features and problems associated with it. There is a need to discuss these issues in order to understand the real meaning of simulator based training and to handle it effectively. Like other fields of training, use of simulation in the maritime industry is owing to the multiple factors covering technological, financial and training needs of the time. When properly used, supported by well trained and experienced instructors, simulator training, through its risk free environment, can contribute to a reduction in accidents and improve capability and efficiency, by providing trainees with the necessary experience and self confidence to carry out their roles, functions and tasks.

  13. Optics Corrections with LOCO in the Fermilab Booster

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Cheng-Yang [Fermilab; Prost, Lionel [Fermilab; Seiya, Kiyomi [Fermilab; Triplett, A. Kent [Fermilab

    2016-06-01

    The optics of the Fermilab Booster has been corrected with LOCO (Linear Optics from Closed Orbits). However, the first corrections did not show any improvement in capture efficiency at injection. A detailed analysis of the results showed that the problem lay in the MADX optics file. Both the quadrupole and chromatic strengths were originally set as constants independent of beam energy. However, careful comparison between the measured and calculated tunes and chromatcity show that these strengths are energy dependent. After the MADX model was modified with these new energy dependent strengths, the LOCO corrected lattice has been applied to Booster. The effect of the corrected lattice will be discussed here.

  14. The Concept of In Loco Parentis in Higher Education.

    Science.gov (United States)

    Harms, Herman Edward

    Institutions of higher education have long stood in loco parentis to their students. This concept is now widely challenged. This paper examines the evolution of the concept and discusses 29 court cases, beginning with a case heard in a Maine court in 1847. The evidence indicates that the future of the concept is unpredictable. Procedural due…

  15. Colleges' Increasing Exposure to Liability: The New "In Loco Parentis."

    Science.gov (United States)

    Szablewicz, James J.; Gibbs, Annette

    1987-01-01

    Outlines the history of the concept of "in loco parentis" and the relationship between college students and their institutions. During the 1960's the concept was no longer evident at the college level, but in the 1980's court trends are beginning to show a rebirth (with revisions) of the doctrine. Includes discussion of court litigation.…

  16. Institutionalizing in Loco Parentis after Gott v. Berea College (1913)

    Science.gov (United States)

    Loss, Christopher P.

    2014-01-01

    Background/Context: The institutionalization of in loco parentis in the wake of Gott v. Berea College (1913) marked a major turning point in the evolution of student management theory and practice. Focusing on the crucial decade of the 1920s, when American higher education first became a mass enterprise, this study explores the interaction of…

  17. "In Loco Parentis": A Relationship Between Parent, State and Child

    Science.gov (United States)

    Shaw, Jenny

    1977-01-01

    Archbishop Ussher (1645) in explaining why all superiors were called parents called upon the idea of patriarchal authority. This paper considers the social implications of the same philosophy as it is represented by the practice of education authorities standing "in loco parentis" to their pupils. (Editor)

  18. Aurelia, nadja y el amor loco Una estetica del amor

    OpenAIRE

    Tapias Ospina, Claudia; Editora Revistas Pluma y Universitas Humanística.

    2004-01-01

    El presente ensayo dilucida la íntima relación existente entre Aurelia de Gérard de Nerval (1) -obra escrita en 1853 en pleno Romanticismo- y Nadja (1928) y El amor loco (1937) de André Bretón -escritas durante el auge del movimiento Surrealista (2).

  19. Simulation analysis of wastes gasification technologies

    Directory of Open Access Journals (Sweden)

    Stępień Leszek

    2017-01-01

    Full Text Available Each year a significant growth in the amount of wastes generated is observed. Due to this fact technologies enabling utilization of wastes are needed. One of the ways to utilizes wastes is thermal conversion. Most widely used technology for thermal conversion is gasification that enables to produce syngas that can be either combusted or directed to further synthesis to produce methanol or liquid fuels. There are several commercially available technologies that enable to gasify wastes. The first part of this study is subjected to general description of waste gasification process. Furthermore the analysis and comparison of commercially available gasification technologies is presented, including their process arrangement, limits and capabilities. Second part of the study is dedicated to the development of thermodynamic model for waste gasification. The model includes three zones of gasification reactors: drying, gasification and eventually ash melting. Modified Gibbs minimization method is used to simulate gasification process. The model is capable of predicting final gas composition as a function of temperature or equivalence ratio. Calculations are performed for a specified average wastes composition and different equivalence ratios of air to discuss its influence on the performance of gasification (temperature of the process and gas composition. Finally the model enables to calculate total energy balance of the process as well as gasification and final gas temperature.

  20. Simulation technology for refrigeration and air conditioning appliances

    Institute of Scientific and Technical Information of China (English)

    DING Guoliang

    2006-01-01

    Simulation technology has been widely used for performance prediction and optimal design of refrigeration and air conditioning appliances. A brief history of simulation technology for refrigeration and air conditioning appliances is reviewed. The models for evaporator, condenser, compressor, capillary tube and thermal insulation layer are summarized, and a fast calculation method for thermodynamic properties of refrigerant is introduced in this paper. The model-based intelligent simulation technology and the simulation technology based on graph theory are also illustrated. Finally, an updated trend of simulation technology development for refrigeration and air conditioning appliances is discussed.

  1. Measurement and Correction of the Fermilab Booster Optics with LOCO*

    CERN Document Server

    Tan, C Y; Triplett, A K; McAteer, M

    2015-01-01

    The optics of the original Booster lacked the ability for full optics correction and it was not until 2009 when new optics corrector packages were installed between gradient magnets that this ability became available. The optics correction method that is chosen is called LOCO (Linear Optics from Closed Orbits) that measures the orbit response from every beam position monitor (BPM) in the ring from every kick of every dipole corrector. The large data set collected allows LOCO to not only calculate the quadrupole and skew quadrupole currents that both reduces beta beatings and corrects coupling, it also finds the dipole kicker strengths, BPM calibrations and their tilts by minimizing the difference between the measured and ideal orbit response of the beam. The corrected optics have been loaded into Booster and it is currently being tested to be eventually used in normal operations.

  2. Technologies of stage magic: Simulation and dissimulation.

    Science.gov (United States)

    Smith, Wally

    2015-06-01

    The craft of stage magic is presented in this article as a site to study the interplay of people and technology. The focus is on conjuring in the 19th and early 20th centuries, a time when magicians eagerly appropriated new optical, mechanical and electrical technologies into their acts. Also at this time, a modern style of conjuring emerged, characterized by minimal apparatus and a natural manner of performance. Applying Lucy Suchman's perspective of human-machine reconfigurations, conjuring in this modern style is interpreted as an early form of simulation, coupled with techniques of dissimulation. Magicians simulated the presence of supernational agency for public audiences, while dissimulating the underlying methods and mechanisms. Dissimulation implies that the secret inner workings of apparatus were not simply concealed but were rendered absent. This, in turn, obscured the production of supernatural effects in the translation of agencies within an assembly of performers, assistants, apparatus, apparatus-builders, and so on. How this was achieved is investigated through an analysis of key instructional texts written by and for magicians working in the modern style. Techniques of dissimulation are identified in the design of apparatus for three stage illusions, and in the new naturalness of the performer's manner. To explore the significance of this picture of stage magic, and its reliance on techniques of dissimulation, a parallel is drawn between conjuring and recent performances of computerized life forms, especially those of social robotics. The paper concludes by considering what is revealed about the production of agency in stage magic's peculiar human-machine assemblies.

  3. Loss in Connectivity (LoCo) among regions of the brain reward system in alcohol dependence

    OpenAIRE

    Kuceyeski, Amy; Meyerhoff, Dieter J.; Timothy C. Durazzo; Raj, Ashish

    2012-01-01

    A recently developed measure of structural brain connectivity disruption, the Loss in Connectivity (LoCo), is adapted for studies in alcohol dependence. LoCo uses independent tractography information from young healthy controls to project the location of white matter microstructure abnormalities in alcohol dependent vs. non-dependent individuals onto connected gray matter regions. The LoCo scores are computed from white matter abnormality masks derived at two levels: 1) group-wise differences...

  4. Modeling and simulation technology readiness levels.

    Energy Technology Data Exchange (ETDEWEB)

    Clay, Robert L.; Shneider, Max S.; Marburger, S. J.; Trucano, Timothy Guy

    2006-01-01

    This report summarizes the results of an effort to establish a framework for assigning and communicating technology readiness levels (TRLs) for the modeling and simulation (ModSim) capabilities at Sandia National Laboratories. This effort was undertaken as a special assignment for the Weapon Simulation and Computing (WSC) program office led by Art Hale, and lasted from January to September 2006. This report summarizes the results, conclusions, and recommendations, and is intended to help guide the program office in their decisions about the future direction of this work. The work was broken out into several distinct phases, starting with establishing the scope and definition of the assignment. These are characterized in a set of key assertions provided in the body of this report. Fundamentally, the assignment involved establishing an intellectual framework for TRL assignments to Sandia's modeling and simulation capabilities, including the development and testing of a process to conduct the assignments. To that end, we proposed a methodology for both assigning and understanding the TRLs, and outlined some of the restrictions that need to be placed on this process and the expected use of the result. One of the first assumptions we overturned was the notion of a ''static'' TRL--rather we concluded that problem context was essential in any TRL assignment, and that leads to dynamic results (i.e., a ModSim tool's readiness level depends on how it is used, and by whom). While we leveraged the classic TRL results from NASA, DoD, and Sandia's NW program, we came up with a substantially revised version of the TRL definitions, maintaining consistency with the classic level definitions and the Predictive Capability Maturity Model (PCMM) approach. In fact, we substantially leveraged the foundation the PCMM team provided, and augmented that as needed. Given the modeling and simulation TRL definitions and our proposed assignment methodology, we

  5. Melanoma targeting with the loco-regional chemotherapeutic, Melphalan: From cell death to immunotherapeutic efficacy.

    Science.gov (United States)

    Dudek-Perić, Aleksandra Maria; Gołąb, Jakub; Garg, Abhishek D; Agostinis, Patrizia

    2015-12-01

    All immunoregulatory chemotherapeutics are chiefly applied in a systemic setting for anticancer therapy. However, immune responses following loco-regional application of chemotherapy may differ from those after systemic application. We recently found that Melphalan, a prototypical loco-regionally applied chemotherapeutic agent, exhibits the ability to increase the immunogenicity of dying melanoma cells.

  6. "In Loco Parentis" Revisited and Commercial Speech on Campus. ASHE 1987 Annual Meeting Paper.

    Science.gov (United States)

    Hobbs, Walter C.

    The applicability of "in loco parentis" and the issue of commercial speech (e.g. sales pitches and advertising) on campus are discussed. While in previous years the principle of in loco parentis allowed colleges to dicate the behavior of its students, colleges must now take reasonable steps to guarantee the physical safety of students.…

  7. Co-Simulation Technology for Complex Product Design

    Institute of Scientific and Technical Information of China (English)

    熊光楞; 陈小波; 郭滨; 蹇佳; 王成龙

    2002-01-01

    First analyze the simulation requirements in complex product design, then propose the approach to full applying simulation to complex product design, and present the key enable technology with respect to modeling, simulation running, VV&A,evaluation and decision making and supporting platform.

  8. Sedimentation survey of Lago Loco, Puerto Rico, March 2000

    Science.gov (United States)

    Soler-López, Luis R.

    2002-01-01

    Lago Loco, a small reservoir property of the Puerto Rico Electric Power Authority and part of the Southwestern Puerto Rico Project, has lost 64 percent of its original storage capacity. In 1951, the original storage capacity was about 2.40 million cubic meters, decreasing to 1.43 million cubic meters in 1986 and to 0.87 million cubic meters in March 2000. The storage loss or longterm sedimentation rate increased from 27,714 cubic meters per year from the period of 1951 to 1986 to 31,224 cubic meters per year for the period of 1951 to 2000. This represents a capacity loss of about 1.1 percent per year for the period of 1951 to 1986 and 1.3 percent per year for 1951 to 2000. The trapping efficiency of the reservoir was about 92 percent in 1951, decreasing to about 87 percent in 1986, and to about 80 percent in March 2000. The sediment yield of the net sediment- contributing drainage area increased from 1,504 megagrams per square kilometer per year between 1951 and 1986 to 1,774 megagrams per square kilometer per year between 1951 and 2000, or about 18 percent. At the current sedimentation rate of the reservoir, the life expectancy of Lago Loco is about 28 more years or until the year 2028.

  9. Photometric Properties of Low-Redshift Galaxy Clusters (LOCOS)

    CERN Document Server

    López-Cruz, O

    2000-01-01

    A comprehensive multicolor survey was undertaken to investigate global optical properties of Abell clusters of galaxies. This survey was christened the "Low-Redshift Cluster Optical Survey" (LOCOS). LOCOS was devised to search for patterns of galaxy evolution induced by the environment. The generated data base contains accurate deep CCD photometric measurements (Kron-Cousins R,,B and I) for a sample of 46 low-redshift (0.04 <= z <= 0.18) Abell clusters. This is one of the few large surveys that included the contribution due to dwarf galaxies (about 5.5 mag deeper than the R characteristic magnitude (M*); Ho=50 km/s/Mpc, qo=0). Due to space restrictions only the main results concerning the variations at the bright-end of the luminosity function (LF) are presented here. Other results are presented elsewhere (Lopez-Cruz & Yee 2000a,b). We have detected clear variations at both the bright end and the faint end of the LF. The nature of the variations at the bright end revealed that poor cD clusters have ...

  10. Simulation of ion implantation for ULSI technology

    CERN Document Server

    Hoessinger, A

    2000-01-01

    approximately constant an almost linear performance gain could be achieved by the parallelization method, even if a fairly slow network connects the workstations. Finally, the developed Monte-Carlo ion implantation simulator is applied to a set of examples making use of some of the special features of the simulator. Additionally a small operating manual for the simulator is included in the appendix. been developed and implemented. These methods enable to treat the implantation of molecular ions and atom clusters and thus the implantation of BF, which is a widely used for the doping with boron atoms. By providing two methods for the simulation of molecular ions the functionality of the simulator can be adapted to the problem requirements. While the simplified molecular method needs less computation time, the full molecular method provides more precise results. Another part of this work was the design and the implementation of a point response interface method. It allows to interface Monte-Carlo simulation resu...

  11. Technology of planetary extreme environment simulation

    Science.gov (United States)

    Wakefield, M. E.; Apodaca, L. E.; Hall, C. A.

    1972-01-01

    Four test chamber systems were devleoped to simulate the extreme atmospheric environs of Venus and Jupiter, in order to assure satisfactory performance of scientific entry probes and their experiments.

  12. Loco-regional therapy for liver cancer%肝癌的局部区域治疗

    Institute of Scientific and Technical Information of China (English)

    叶胜龙

    2013-01-01

    局部区域治疗在影像学引导下靶向杀伤肿瘤,是原发性肝癌最主要的非手术治疗方法,包括放射介入治疗(主要为肝动脉化疗栓塞)和局部消融治疗(瘤内乙醇注射、射频、微波、激光、高强度聚焦超声、冷冻等治疗).肝动脉化疗栓塞主要应用于不能手术切除的中晚期肝癌,局部消融治疗适用于直径5 cm以下的小肝癌.肝癌局部区域治疗强调针对具体病情选择合适的方法进行规范治疗.本文简要评述各种局部区域治疗方法的指征、治疗原则、技术要点和疗效,并讨论手术切除与局部消融治疗小肝癌的选择.%Loco-regional therapy, which uses imaging technologies to facilitate targeted delivery of therapeutic agents to cancers, has emerged as the most commonly used non-surgical treatment for primary liver cancer. Since the theory of loco-regional therapy was introduced, various strategies have been developed and successfully applied in clinic, including interventional radiology methods ( mainly transarterial chemoembo-lization) and local ablative methods (such as intratumoral ethanol injection, radiofrequency ablation, microwave coagulation, laser-induced thermal therapy, high-intensity focused ultrasound, and cryotherapy). TACE has been widely applied to treat inoperable liver cancers at intermediate and advanced stages, while the local ablative therapies have proven more suitable for small ( <5 cm) liver cancers. However, choosing the appropriate loco -regional therapy strategy should be carried out on an individual basis, considering the patients particular disease condition and characteristics. To help guide such treatment decisions, this review highlights the principal indications, theory, techniques, and reported efficacies of the various loco-regional therapy strategies.

  13. Enabling Computational Technologies for Terascale Scientific Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Ashby, S.F.

    2000-08-24

    We develop scalable algorithms and object-oriented code frameworks for terascale scientific simulations on massively parallel processors (MPPs). Our research in multigrid-based linear solvers and adaptive mesh refinement enables Laboratory programs to use MPPs to explore important physical phenomena. For example, our research aids stockpile stewardship by making practical detailed 3D simulations of radiation transport. The need to solve large linear systems arises in many applications, including radiation transport, structural dynamics, combustion, and flow in porous media. These systems result from discretizations of partial differential equations on computational meshes. Our first research objective is to develop multigrid preconditioned iterative methods for such problems and to demonstrate their scalability on MPPs. Scalability describes how total computational work grows with problem size; it measures how effectively additional resources can help solve increasingly larger problems. Many factors contribute to scalability: computer architecture, parallel implementation, and choice of algorithm. Scalable algorithms have been shown to decrease simulation times by several orders of magnitude.

  14. Virtual Reality Simulator Developed Welding Technology Skills

    Science.gov (United States)

    Yunus, Faizal Amin Nur; Baser, Jamil Abd; Masran, Saiful Hadi; Razali, Nizamuddin; Rahim, Bekri

    2011-01-01

    The purpose of this study was to identify the suitability of VR welding simulator application towards CBT in developing welding skills upon new trainees at the Centre of Instructor and Advanced Skills Training (CIAST) Shah Alam Selangor and National Youth Skills Institute (IKBN) Pagoh Johor. The significance of the study was to create a…

  15. Technology computer aided design simulation for VLSI MOSFET

    CERN Document Server

    Sarkar, Chandan Kumar

    2013-01-01

    Responding to recent developments and a growing VLSI circuit manufacturing market, Technology Computer Aided Design: Simulation for VLSI MOSFET examines advanced MOSFET processes and devices through TCAD numerical simulations. The book provides a balanced summary of TCAD and MOSFET basic concepts, equations, physics, and new technologies related to TCAD and MOSFET. A firm grasp of these concepts allows for the design of better models, thus streamlining the design process, saving time and money. This book places emphasis on the importance of modeling and simulations of VLSI MOS transistors and

  16. Technology for Simulating Crowd Evacuation Behaviors

    Institute of Scientific and Technical Information of China (English)

    Wen-Hu Qin; Guo-Hui Su; Xiao-Na Li

    2009-01-01

    This paper presents a model for simulating crowd evacuation and investigates three widely recognized problems. For the space continuity problem, this paper presents two computation algorithms: one uses grid space to evaluate the coordinates of the obstacle's bounding box and the other employs the geometry rule to establish individual evacuation routes. For the problem of collision, avoidance, and excess among the individuals, this paper computes the generalized force and friction force and then modifies the direction of march to obtain a speed model based on the crowd density and real time speed. For the exit selection problem, this paper establishes a method of selecting the exits by combining the exit's crowd state with the individuals. Finally, a particle system is used to simulate the behavior of crowd evacuation and produces useful test results.

  17. Supporting the Transfer of Simulation Technology

    Science.gov (United States)

    1989-07-01

    projects and languages. We would also like to thank Judith Westbury for editing this report and Mary Aguilar for her assis- tance in processing it...Hausner, and Karr, 1962) and Simscript II (Kiviat, Villanueva , and Markowitz, 1968), as well as theoretical and experimental results in game theory...P. J., Digital Computer Simulation: Computer Programming Languages, The RAND Corporation, RM-5883-PR, January 1969. Kiviat, P. J., R. Villanueva , and

  18. Simulation of Mine Electrical Penetration Technology

    Institute of Scientific and Technical Information of China (English)

    LIU Zhi-xin; YUE Jian-hua; LIU Shu-cai

    2007-01-01

    Based on the principle of electrical penetration, the reflection characteristics of collapse columns at different locations of a working face is numerically simulated by using a 3D finite element method. The data collected by the electrical penetration is processed and interpreted using "tunnel penetration" which is similar to radio wave penetration. Reflection characteristics of collapse columns at different locations below floors of coal seams are analyzed, providing a new paradigm and a theoretical foundation for processing and interpreting electrical penetration data. The tomography analysis is made based on data simulation and calculation results and alltransmitting-receiving points are analyzed for their corresponding maximum attenuation values and maximum absorption coefficients. On the basis of this, a new method for precisely interpreting the spatial positions of geological anomalous bodies is suggested. The simulation shows that 1) the detection result of both roof and floors of the working face by electrical penetration is a volumetric effect and 2) there exists a corresponding relation between the detection depth and the working face width, with the optimal detection depth within 40% of the working face width.

  19. Medical simulation technology: educational overview, industry leaders, and what's missing.

    Science.gov (United States)

    Spooner, Nicholas; Hurst, Stephen; Khadra, Mohamed

    2012-01-01

    Modern medical simulation technology (MST) debuted in 1960 with the development of Resusci Annie (Laerdal 2007), which assisted students in the acquisition of proper ventilation and compression techniques used during basic life support. Following a steady stream of subsequent technological advances and innovations, MST manufacturers are now able to offer training aids capable of facilitating innovative learning in such diverse areas as human patient simulators, simulated clinical environments, virtual procedure stations, virtual medical environments, electronic tutors, and performance recording. The authors list a number of the most popular MSTs presently available while citing evaluative efforts undertaken to date regarding the efficacy of MST to the medical profession. They conclude by proposing a variety of simulation innovations of prospective interest to both medical and technology personnel while offering healthcare administrators a series of recommended considerations when planning to integrate MST into existing medical systems.

  20. Evolution of Responsibility: From "In Loco Parentis" to "Ad Meliora Vertamur"

    Science.gov (United States)

    Bowden, Randall

    2007-01-01

    This paper provides a perspective of the evolution of the doctrine of "in loco parentis" to contract law to a doctrine of responsibility of care--a sense of "ad meliora vertamur" (let us turn to better things). It provides a brief history of "in loco parentis" as it has developed in the U.S. as well as the difficulties it faces in modern academe.…

  1. Using Simulations to Integrate Technology into Health Care Aidesཿ Workflow

    Directory of Open Access Journals (Sweden)

    Sharla King

    2013-07-01

    Full Text Available Health care aides (HCAs are critical to home care, providing a range of services to people with chronic conditions, aging or are unable to care for themselves independently. The current HCA supply will not keep up with this increasing demand without fundamental changes in their work environment. One possible solution to some of the workflow challenges and workplace stress of HCAs is hand-held tablet technology. In order to introduce the use of tablets with HCAs, simulations were developed. Once an HCA was comfortable with the tablet, a simulated client was introduced. The HCA interacted with the simulated client and used the tablet applications to assist with providing care. After the simulations, the HCAs participated in a focus group. HCAs completed a survey before and after the tablet training and simulation to determine their perception and acceptance of the tablet. Future deployment and implementation of technologies in home care should be further evaluated for outcomes.

  2. Arabidopsis Growth Simulation Using Image Processing Technology

    Directory of Open Access Journals (Sweden)

    Junmei Zhang

    2014-01-01

    Full Text Available This paper aims to provide a method to represent the virtual Arabidopsis plant at each growth stage. It includes simulating the shape and providing growth parameters. The shape is described with elliptic Fourier descriptors. First, the plant is segmented from the background with the chromatic coordinates. With the segmentation result, the outer boundary series are obtained by using boundary tracking algorithm. The elliptic Fourier analysis is then carried out to extract the coefficients of the contour. The coefficients require less storage than the original contour points and can be used to simulate the shape of the plant. The growth parameters include total area and the number of leaves of the plant. The total area is obtained with the number of the plant pixels and the image calibration result. The number of leaves is derived by detecting the apex of each leaf. It is achieved by using wavelet transform to identify the local maximum of the distance signal between the contour points and the region centroid. Experiment result shows that this method can record the growth stage of Arabidopsis plant with fewer data and provide a visual platform for plant growth research.

  3. Interoperable Technologies for Advanced Petascale Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaolin [SUNY at Stony Brook

    2013-01-14

    Our final report on the accomplishments of ITAPS at Stony Brook during period covered by the research award includes component service, interface service and applications. On the component service, we have designed and implemented a robust functionality for the Lagrangian tracking of dynamic interface. We have migrated the hyperbolic, parabolic and elliptic solver from stage-wise second order toward global second order schemes. We have implemented high order coupling between interface propagation and interior PDE solvers. On the interface service, we have constructed the FronTier application programer's interface (API) and its manual page using doxygen. We installed the FronTier functional interface to conform with the ITAPS specifications, especially the iMesh and iMeshP interfaces. On applications, we have implemented deposition and dissolution models with flow and implemented the two-reactant model for a more realistic precipitation at the pore level and its coupling with Darcy level model. We have continued our support to the study of fluid mixing problem for problems in inertial comfinement fusion. We have continued our support to the MHD model and its application to plasma liner implosion in fusion confinement. We have simulated a step in the reprocessing and separation of spent fuels from nuclear power plant fuel rods. We have implemented the fluid-structure interaction for 3D windmill and parachute simulations. We have continued our collaboration with PNNL, BNL, LANL, ORNL, and other SciDAC institutions.

  4. Plasma arc cutting technology: simulation and experiments

    Energy Technology Data Exchange (ETDEWEB)

    Cantoro, G; Colombo, V; Concetti, A; Ghedini, E; Sanibondi, P; Zinzani, F; Rotundo, F [Department of Mechanical Engineering (D.I.E.M.) and Research Center for Applied Mathematics (C.I.R.A.M.), Alma Mater Studiorum-Universita di Bologna, Via Saragozza 8, 40123 Bologna (Italy); Dallavalle, S; Vancini, M, E-mail: emanuele.ghedini@unibo.it [Cebora S.p.A., Via Andrea Costa 24, 40057 Cadriano di Granarolo (Italy)

    2011-01-01

    Transferred arc plasma torches are widely used in industrial processes for cutting of metallic materials because of their ability to cut a wide range of metals with very high productivity. The process is characterized by a transferred electric arc established between an electrode inside the torch (the cathode) and another electrode, the metallic workpiece to be cut (the anode). In order to obtain a high quality cut and a high productivity, the plasma jet must be as collimated as possible and must have the higher achievable power density. Plasma modelling and numerical simulation can be very useful tools for the designing and optimizing these devices, but research is still in the making for finding a link between simulation of the plasma arc and a consistent prevision of cut quality. Numerical modelling of the behaviour of different types of transferred arc dual gas plasma torches can give an insight on the physical reasons for the industrial success of various design and process solutions that have appeared over the last years. Diagnostics based on high speed imaging and Schlieren photography can play an important role for investigating piercing, dross generation, pilot arcing and anode attachment location. Also, the behaviour of hafnium cathodes at high current levels at the beginning of their service life can been experimentally investigated, with the final aim of understanding the phenomena that take place during those initial piercing and cutting phases and optimizing the initial shape of the surface of the emissive insert exposed to plasma atmosphere.

  5. Sensitivity technologies for large scale simulation.

    Energy Technology Data Exchange (ETDEWEB)

    Collis, Samuel Scott; Bartlett, Roscoe Ainsworth; Smith, Thomas Michael; Heinkenschloss, Matthias (Rice University, Houston, TX); Wilcox, Lucas C. (Brown University, Providence, RI); Hill, Judith C. (Carnegie Mellon University, Pittsburgh, PA); Ghattas, Omar (Carnegie Mellon University, Pittsburgh, PA); Berggren, Martin Olof (University of UppSala, Sweden); Akcelik, Volkan (Carnegie Mellon University, Pittsburgh, PA); Ober, Curtis Curry; van Bloemen Waanders, Bart Gustaaf; Keiter, Eric Richard

    2005-01-01

    Sensitivity analysis is critically important to numerous analysis algorithms, including large scale optimization, uncertainty quantification,reduced order modeling, and error estimation. Our research focused on developing tools, algorithms and standard interfaces to facilitate the implementation of sensitivity type analysis into existing code and equally important, the work was focused on ways to increase the visibility of sensitivity analysis. We attempt to accomplish the first objective through the development of hybrid automatic differentiation tools, standard linear algebra interfaces for numerical algorithms, time domain decomposition algorithms and two level Newton methods. We attempt to accomplish the second goal by presenting the results of several case studies in which direct sensitivities and adjoint methods have been effectively applied, in addition to an investigation of h-p adaptivity using adjoint based a posteriori error estimation. A mathematical overview is provided of direct sensitivities and adjoint methods for both steady state and transient simulations. Two case studies are presented to demonstrate the utility of these methods. A direct sensitivity method is implemented to solve a source inversion problem for steady state internal flows subject to convection diffusion. Real time performance is achieved using novel decomposition into offline and online calculations. Adjoint methods are used to reconstruct initial conditions of a contamination event in an external flow. We demonstrate an adjoint based transient solution. In addition, we investigated time domain decomposition algorithms in an attempt to improve the efficiency of transient simulations. Because derivative calculations are at the root of sensitivity calculations, we have developed hybrid automatic differentiation methods and implemented this approach for shape optimization for gas dynamics using the Euler equations. The hybrid automatic differentiation method was applied to a first

  6. Sensitivity technologies for large scale simulation.

    Energy Technology Data Exchange (ETDEWEB)

    Collis, Samuel Scott; Bartlett, Roscoe Ainsworth; Smith, Thomas Michael; Heinkenschloss, Matthias (Rice University, Houston, TX); Wilcox, Lucas C. (Brown University, Providence, RI); Hill, Judith C. (Carnegie Mellon University, Pittsburgh, PA); Ghattas, Omar (Carnegie Mellon University, Pittsburgh, PA); Berggren, Martin Olof (University of UppSala, Sweden); Akcelik, Volkan (Carnegie Mellon University, Pittsburgh, PA); Ober, Curtis Curry; van Bloemen Waanders, Bart Gustaaf; Keiter, Eric Richard

    2005-01-01

    Sensitivity analysis is critically important to numerous analysis algorithms, including large scale optimization, uncertainty quantification,reduced order modeling, and error estimation. Our research focused on developing tools, algorithms and standard interfaces to facilitate the implementation of sensitivity type analysis into existing code and equally important, the work was focused on ways to increase the visibility of sensitivity analysis. We attempt to accomplish the first objective through the development of hybrid automatic differentiation tools, standard linear algebra interfaces for numerical algorithms, time domain decomposition algorithms and two level Newton methods. We attempt to accomplish the second goal by presenting the results of several case studies in which direct sensitivities and adjoint methods have been effectively applied, in addition to an investigation of h-p adaptivity using adjoint based a posteriori error estimation. A mathematical overview is provided of direct sensitivities and adjoint methods for both steady state and transient simulations. Two case studies are presented to demonstrate the utility of these methods. A direct sensitivity method is implemented to solve a source inversion problem for steady state internal flows subject to convection diffusion. Real time performance is achieved using novel decomposition into offline and online calculations. Adjoint methods are used to reconstruct initial conditions of a contamination event in an external flow. We demonstrate an adjoint based transient solution. In addition, we investigated time domain decomposition algorithms in an attempt to improve the efficiency of transient simulations. Because derivative calculations are at the root of sensitivity calculations, we have developed hybrid automatic differentiation methods and implemented this approach for shape optimization for gas dynamics using the Euler equations. The hybrid automatic differentiation method was applied to a first

  7. Regulation of longevity by regulator of G-protein signaling protein, Loco.

    Science.gov (United States)

    Lin, Yuh-Ru; Kim, Keetae; Yang, Yanfei; Ivessa, Andreas; Sadoshima, Junichi; Park, Yongkyu

    2011-06-01

    Regulator of G-protein signaling (RGS) proteins contribute to G-protein signaling pathways as activators or repressors with GTPase-activating protein (GAP) activity. To characterize whether regulation of RGS proteins influences longevity in several species, we measured stress responses and lifespan of RGS-overexpressing and RGS-lacking mutants. Reduced expression of Loco, a RGS protein of Drosophila melanogaster, resulted in a longer lifespan for both male and female flies, also exhibiting stronger resistance to three different stressors (starvation, oxidation, and heat) and higher manganese-containing superoxide dismutase (MnSOD) activity. In addition, this reduction in Loco expression increased fat content and diminished cAMP levels. In contrast, overexpression of both genomic and cDNA loco gene significantly shortened the lifespan with weaker stress resistance and lower fat content. Deletion analysis of the Loco demonstrated that its RGS domain is required for the regulation of longevity. Consistently, when expression of RGS14, mammalian homologue of Loco, was reduced in rat fibroblast cells, the resistance to oxidative stress increased with higher MnSOD expression. The changes of yeast Rgs2 expression, which shares a conserved RGS domain with the fly Loco protein, also altered lifespan and stress resistance in Saccharomyces cerevisiae. Here, we provide the first evidence that RGS proteins with GAP activity affect both stress resistance and longevity in several species.

  8. Predictors of loco-regional recurrence and cancer-related death after breast cancer surgery.

    Science.gov (United States)

    Rausei, Stefano; Rovera, Francesca; Dionigi, Gianlorenzo; Tornese, Deborah; Fachinetti, Anna; Boni, Luigi; Dionigi, Renzo

    2010-01-01

    To determine which tumor-related factors might predispose the patient to loco-regional recurrence or death and the impact of these factors on the different types of events. We retrospectively analyzed the data of 1991 women between January 1998 and March 2010 for a first primary nonmetastatic breast cancer and treated with surgery and neo-adjuvant/adjuvant therapy. The overall survival distribution was estimated using the Kaplan-Meier method. The prognostic impact of several factors on cumulative overall and loco-regional recurrence free survival was evaluated by univariate (log-rank test) and multivariate analysis (Cox regression). At log-rank test, pT, nodal status, histotype, grading, lymphangioinvasive growth, tumor diameter, estrogen receptors (ER) status, progesterone receptors (PR) status, expression of Ki67, and expression of Her2/neu had a prognostic value on loco-regional recurrence or overall survival. In the multivariate analysis grading remained the only independent predictor of loco-regional recurrences. With regard to overall survival, the Cox model selected grading along with nodal status and PR status. Loco-regional recurrences after breast cancer surgery are not frequent events. They are markers of tumor aggressiveness and predictor of an increased likelihood of cancer-related death. However, loco-regional recurrence and systemic tumor progression are partially independent events, since some prognostic factors differ.

  9. Interoperable Technologies for Advanced Petascale Simulations (ITAPS)

    Energy Technology Data Exchange (ETDEWEB)

    Shephard, Mark S

    2010-02-05

    Efforts during the past year have contributed to the continued development of the ITAPS interfaces and services as well as specific efforts to support ITAPS applications. The ITAPS interface efforts have two components. The first is working with the ITAPS team on improving the ITAPS software infrastructure and level of compliance of our implementations of ITAPS interfaces (iMesh, iMeshP, iRel and iGeom). The second is being involved with the discussions on the design of the iField fields interface. Efforts to move the ITAPS technologies to petascale computers has identified a number of key technical developments that are required to effectively execute the ITAPS interfaces and services. Research to address these parallel method developments has been a major emphasis of the RPI’s team efforts over the past year. Efforts to move the ITAPS technologies to petascale computers has identified a number of key technical developments that are required to effectively execute the ITAPS interfaces and services. Research to address these parallel method developments has been a major emphasis of the RPI’s team efforts over the past year. The development of parallel unstructured mesh methods has considered the need to scale unstructured mesh solves to massively parallel computers. These efforts, summarized in section 2.1 show that with the addition of the ITAPS procedures described in sections 2.2 and 2.3 we are able to obtain excellent strong scaling with our unstructured mesh CFD code on up to 294,912 cores of IBM Blue Gene/P which is the highest core count machine available. The ITAPS developments that have contributed to the scaling and performance of PHASTA include an iterative migration algorithm to improve the combined region and vertex balance of the mesh partition, which increases scalability, and mesh data reordering, which improves computational performance. The other developments are associated with the further development of the ITAPS parallel unstructured mesh

  10. Simulation studies for the evaluation of health information technologies

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner; Binzer, Kristine

    2012-01-01

    It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...... is not sufficiently mature. Laboratory-based evaluations have also been shown to have insufficient external validity. Simulation studies seem to be a way to bridge this gap. The aim of this study was to evaluate, using a simulation methodology, the impact of a new prototype of an electronic medication management...

  11. Recent Achievements in Simulated Moving Bed (SMB Technology. Part II

    Directory of Open Access Journals (Sweden)

    Roje, M.

    2010-09-01

    Full Text Available Progress in the method of simulated moving bed (SMB technology and some important achievements in separation of specific classes of racemic compounds of therapeutic interest are reported in the Part I of this review. Part II describes novel methods of SMB technology. Complex technologies,such as the combination of SMB and biocatalytic reactions, and SMB with crystallization process, are presented. VariCol variant of SMB, and its application in the separation of the racemic mixtures of commercial and academic interest are discussed. In the conclusive section, comments are given concerning the economic dimension and the market of enantiomerically pure compounds.

  12. Simulation-Based Evaluation of Learning Sequences for Instructional Technologies

    Science.gov (United States)

    McEneaney, John E.

    2016-01-01

    Instructional technologies critically depend on systematic design, and learning hierarchies are a commonly advocated tool for designing instructional sequences. But hierarchies routinely allow numerous sequences and choosing an optimal sequence remains an unsolved problem. This study explores a simulation-based approach to modeling learning…

  13. [Loco-regional chemotherapy at the outpatient clinic for gastric cancer patients with home enteral nutrition].

    Science.gov (United States)

    Maruyama, Michio; Nagahama, Takeshi; Sugano, Norihide; Satoh, Eigo; Maruyama, Shouji; Tanami, Hideo; Chiba, Tetsuma; Murakata, Ayano; Mitsuhashi, Yosuke; Uehira, Daisuke; Akazawa, Naoya; Suzuki, Keiichirou

    2011-11-01

    In over the 10 years from 2000-2010, 21 gastric cancer patients received loco-regional chemotherapy with home enteral nutrition (HEN) at an outpatient clinic because of insufficient oral intake. These loco-regional chemotherapy regimens consisted of 5 intra-aortic chemotherapies, 4 hepato-arterial infusions and 12 intra-peritoneal chemotherapies. Five out of 8 cases that had measurable lesions showed PR, and 3 cases revealed PD. The patients received HEN with peptide central formula, 400-1,200 kcal/day in night time. The average duration of HEN was 12.9 months. The post-operative nutritional management was needed for continuation and securing of outpatient chemotherapy. The author reported an experience of the outpatient loco-regional chemotherapy with HEN for the gastric cancer patients who could not eat a sufficient volume of food.

  14. Simulation studies for the evaluation of health information technologies

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner; Binzer, Kristine

    2012-01-01

    It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...... is not sufficiently mature. Laboratory-based evaluations have also been shown to have insufficient external validity. Simulation studies seem to be a way to bridge this gap. The aim of this study was to evaluate, using a simulation methodology, the impact of a new prototype of an electronic medication management...... and lessons learnt while conducting the study. Although the new electronic medication management system showed tendencies to improve medication safety when compared with the standard system, this tendency was not significant. Altogether, five distinct situations were identified where the new medication...

  15. Simulation Studies for the evaluation of health information technologies:

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner O; Binzer, Kristine

    2012-01-01

    It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...... is not sufficiently mature. Laboratory-based evaluations have also been shown to have insufficient external validity. Simulation studies seem to be a way to bridge this gap. The aim of this study was to evaluate, using a simulation methodology, the impact of a new prototype of an electronic medication management...... and lessons learnt while conducting the study. Although the new electronic medication management system showed tendencies to improve medication safety when compared with the standard system, this tendency was not significant. Altogether, fi ve distinct situations were identifi ed where the new medication...

  16. Magnetic resonance imaging of the liver after loco-regional and systemic therapy.

    Science.gov (United States)

    Corona-Villalobos, Celia Pamela; Zhang, Yan; Zhang, Wei-Dong; Kamel, Ihab R

    2014-08-01

    Assessment of tumor response is crucial in determining the effectiveness of loco-regional and systemic therapy, and for determining the need for subsequent treatment. The ultimate goal is to improve patient's survival. Changes in tumor size and enhancement after therapy may not be detected early by the traditional response criteria. Tumor response is better assessed in the entire tumor volume rather than in a single axial plane. The purpose of this article is to familiarize the reader with early treatment response assessed by anatomic and volumetric functional magnetic resonance imaging metrics of the liver after loco-regional and systemic therapy.

  17. Using Soft Computing Technologies for the Simulation of LCAC Dynamics

    Science.gov (United States)

    2011-09-01

    real-time, time-domain predictions of the vehicle’s dynamics as a function of the control signals given by the driver. Results are presented...free- running LCAC model, faster-than-real-time simulation, soft computing technology 1.0 INTRODUCTION The Maneuvering and Control Division (MCD...like all hovercraft , rides on a cushion of air. The air is supplied to the cushion by four centrifugal fans driven by the craft’s gas turbine

  18. Modelling and simulation SSM: latest state of the art technology

    CSIR Research Space (South Africa)

    Jahajeeah, N

    2005-10-01

    Full Text Available during filling stage Supporting the Manufacturing and Materials Industry in its quest for global competitiveness ? Shear rate history important factor in design and casting processes ? Viscosity decreases over time after applied shear rate ? Ideally... and Materials Industry in its quest for global competitiveness Modelling and Simulation SSM Latest state of the art technology N Jahajeeah Supporting the Manufacturing and Materials Industry in its quest for global competitiveness BEHAVIOUR OF THIXOTROPIC...

  19. Materials, Chemistry, and Simulation for Future Energy Technology.

    Science.gov (United States)

    Aguey-Zinsou, Kondo-Francois; Wang, Da-Wei; Su, Dang-Sheng

    2015-09-01

    Special Issue: The Future of Energy. The science and engineering of clean energy now is becoming a multidisciplinary area, typically when new materials, chemistry, or mechanisms are met. "Trial and error" is the past. Exploration of new concepts for future clean energy can be accomplished through computer-aided materials design and reaction simulation, thanks to innovations in information technologies. This special issue, a fruit of the Energy Future Conference organized by UNSW Australia, has compiled some excellent examples of such approaches.

  20. Molecular dynamics simulations through GPU video games technologies

    Science.gov (United States)

    Loukatou, Styliani; Papageorgiou, Louis; Fakourelis, Paraskevas; Filntisi, Arianna; Polychronidou, Eleftheria; Bassis, Ioannis; Megalooikonomou, Vasileios; Makałowski, Wojciech; Vlachakis, Dimitrios; Kossida, Sophia

    2016-01-01

    Bioinformatics is the scientific field that focuses on the application of computer technology to the management of biological information. Over the years, bioinformatics applications have been used to store, process and integrate biological and genetic information, using a wide range of methodologies. One of the most de novo techniques used to understand the physical movements of atoms and molecules is molecular dynamics (MD). MD is an in silico method to simulate the physical motions of atoms and molecules under certain conditions. This has become a state strategic technique and now plays a key role in many areas of exact sciences, such as chemistry, biology, physics and medicine. Due to their complexity, MD calculations could require enormous amounts of computer memory and time and therefore their execution has been a big problem. Despite the huge computational cost, molecular dynamics have been implemented using traditional computers with a central memory unit (CPU). A graphics processing unit (GPU) computing technology was first designed with the goal to improve video games, by rapidly creating and displaying images in a frame buffer such as screens. The hybrid GPU-CPU implementation, combined with parallel computing is a novel technology to perform a wide range of calculations. GPUs have been proposed and used to accelerate many scientific computations including MD simulations. Herein, we describe the new methodologies developed initially as video games and how they are now applied in MD simulations. PMID:27525251

  1. Simulator platform for fast reactor operation and safety technology demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Vilim, R. B.; Park, Y. S.; Grandy, C.; Belch, H.; Dworzanski, P.; Misterka, J. (Nuclear Engineering Division)

    2012-07-30

    A simulator platform for visualization and demonstration of innovative concepts in fast reactor technology is described. The objective is to make more accessible the workings of fast reactor technology innovations and to do so in a human factors environment that uses state-of-the art visualization technologies. In this work the computer codes in use at Argonne National Laboratory (ANL) for the design of fast reactor systems are being integrated to run on this platform. This includes linking reactor systems codes with mechanical structures codes and using advanced graphics to depict the thermo-hydraulic-structure interactions that give rise to an inherently safe response to upsets. It also includes visualization of mechanical systems operation including advanced concepts that make use of robotics for operations, in-service inspection, and maintenance.

  2. Ship electric propulsion simulator based on networking technology

    Science.gov (United States)

    Zheng, Huayao; Huang, Xuewu; Chen, Jutao; Lu, Binquan

    2006-11-01

    According the new ship building tense, a novel electric propulsion simulator (EPS) had been developed in Marine Simulation Center of SMU. The architecture, software function and FCS network technology of EPS and integrated power system (IPS) were described. In allusion to the POD propeller in ship, a special physical model was built. The POD power was supplied from the simulative 6.6 kV Medium Voltage Main Switchboard, its control could be realized in local or remote mode. Through LAN, the simulated feature information of EPS will pass to the physical POD model, which would reflect the real thruster working status in different sea conditions. The software includes vessel-propeller math module, thruster control system, distribution and emergency integrated management, double closed loop control system, vessel static water resistance and dynamic software; instructor main control software. The monitor and control system is realized by real time data collection system and CAN bus technology. During the construction, most devices such as monitor panels and intelligent meters, are developed in lab which were based on embedded microcomputer system with CAN interface to link the network. They had also successfully used in practice and would be suitable for the future demands of digitalization ship.

  3. Basic technology development of a real-time graphic simulator

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Jae Wook; Hong, Soon Hyuk; Lee, Kyung Hoon; Lee, Sang-Hyun; Lee, Hee Sub [Sungkyunkwan Univ., Seoul (Korea)

    2001-04-01

    In this research, we developed the basic technology of a Real-time graphic simulator for remote monitoring in hostile environment, the Spent Fuel Disassembling facility. The use of a real-time graphic simulator is very useful for building virtual workcell and simulating the virtual devices to preview the behavior of real devices in order to reduce the error in design step of devices and to evaluate and optimize the work processes. And also, it can be used to provide the visualization of operation information from working devices to ensure the reliable monitoring in the teleoperation system. Thus, the development of basic technology related to these is needed. In this system, because the Spent Fuel Disassembling facility should be managed in remote environment due to its characteristics, the transmission of operational information through the network should be used. And for real-time monitoring, the real-time visualization of operational information from real system should be available. Therefore, we defined the efficient message protocol format for real-time transmission of operational information to visualize these in the 3D graphic simulator. 14 refs., 44 figs., 2 tabs. (Author)

  4. Quantitative identification of technological discontinuities using simulation modeling

    CERN Document Server

    Park, Hyunseok

    2016-01-01

    The aim of this paper is to develop and test metrics to quantitatively identify technological discontinuities in a knowledge network. We developed five metrics based on innovation theories and tested the metrics by a simulation model-based knowledge network and hypothetically designed discontinuity. The designed discontinuity is modeled as a node which combines two different knowledge streams and whose knowledge is dominantly persistent in the knowledge network. The performances of the proposed metrics were evaluated by how well the metrics can distinguish the designed discontinuity from other nodes on the knowledge network. The simulation results show that the persistence times # of converging main paths provides the best performance in identifying the designed discontinuity: the designed discontinuity was identified as one of the top 3 patents with 96~99% probability by Metric 5 and it is, according to the size of a domain, 12~34% better than the performance of the second best metric. Beyond the simulation ...

  5. Technology for enhancing chest auscultation in clinical simulation.

    Science.gov (United States)

    Ward, Jeffrey J; Wattier, Bryan A

    2011-06-01

    The ability to use an acoustic stethoscope to detect lung and/or heart sounds, and then to then communicate one's interpretation of those sounds is an essential skill for many medical professionals. Interpretation of lung and heart sounds, in the context of history and other examination findings, often aids the differential diagnosis. Bedside assessment of changing auscultation findings may also guide treatment. Learning lung and heart auscultation skills typically involves listening to pre-recorded normal and adventitious sounds, often followed by laboratory instruction to guide stethoscope placement, and finally correlating the sounds with the associated pathophysiology and pathology. Recently, medical simulation has become an important tool for teaching prior to clinical practice, and for evaluating bedside auscultation skills. When simulating cardiovascular or pulmonary problems, high-quality lung and heart sounds should be able to accurately corroborate other findings such as vital signs, arterial blood gas values, or imaging. Digital audio technology, the Internet, and high-fidelity simulators have increased opportunities for educators and learners. We review the application of these technologies and describe options for reproducing lung and heart sounds, as well as their advantages and potential limitations.

  6. Pedagogical "In Loco Parentis": Reflecting on Power and Parental Authority in the Writing Classroom

    Science.gov (United States)

    Podis, JoAnne; Podis, Leonard

    2007-01-01

    In higher education, issues of "in loco parentis" have been most often discussed in connection with campus administrative policies. College writing teachers need to reflect, however, on the ways they conceivably exercise parental authority in their own classrooms, through such models as the Stern Father and the Nurturing Mother. (Contains 26…

  7. [Role of loco-regional treatments for patients with breast cancer liver metastases].

    Science.gov (United States)

    Raimondi, Cristina; Danova, Marco; Chatzileontiadou, Sofia; Palmeri, Laura; Vercelli, Alessandro; Palmeri, Sergio

    2009-09-01

    Breast cancer liver metastases (BCLM) are not uncommon (about 18% of cases): although some patients have been reported as still living after 25 months, median survival after hormonal- or chemotherapy is 6-14 months. In recent years, new chemotherapy regimens and molecular targeted therapies have given medical oncologists reason to believe that metastatic disease can be eradicated, or at least controlled for prolonged periods. In an attempt to improve survival, consideration has also been given to loco-regional treatments such as hepatic resection and radio-frequency ablation, which have been associated with better outcomes in selected patients. This review considers the role of two loco-regional approaches in a multidisciplinary perspective in the treatment of single or multiple breast cancer metastases limited to the liver. An expanded role for hepatic resection and ablation is being investigated. We assessed available data in the literature to determine their role on survival outcomes. They suggest that loco-regional treatments might be of significant benefit in a selected group of women with BCLM, but the role of these local treatments in multimodality treatment of liver metastases remains controversial. It can generally be said that loco-regional treatments can improve overall survival, with no mortality and less than 20% morbidity in patients at low surgical risk; however, they should only be considered cytoreductive treatments and, as such, always need to be integrated with systemic therapy.

  8. In Loco Parentis and the New Age of Majority: The Views of Freshmen and Their Parents

    Science.gov (United States)

    Devine, Howard F.; Loesch, Larry C.

    1976-01-01

    Research has shown parents have strongly favored in loco parentis and students have not. This study found that, despite the increasing recognition of 18 as legal adulthood, there are still differences between attitudes of students and parents regarding the university's parental role, although both groups favored some university control. (Author)

  9. In Loco Parentis: Alive and Kicking, Dead and Buried, or Rising Phoenix? ASHE Annual Meeting Paper.

    Science.gov (United States)

    Edwards, Alan F., Jr.

    This paper reviews the conflicting literature on "in loco parentis" as applied to college settings. Specifically, attention is focused on three areas: (1) the roots, origins, and early history of the concept; (2) the concept's apparent demise in the 1960s; and (3) its recent comeback as a hot topic. The doctrine of "in loco…

  10. Pedagogical "In Loco Parentis": Reflecting on Power and Parental Authority in the Writing Classroom

    Science.gov (United States)

    Podis, JoAnne; Podis, Leonard

    2007-01-01

    In higher education, issues of "in loco parentis" have been most often discussed in connection with campus administrative policies. College writing teachers need to reflect, however, on the ways they conceivably exercise parental authority in their own classrooms, through such models as the Stern Father and the Nurturing Mother. (Contains 26…

  11. The Lunar Occultation Observer (LOCO) - A Nuclear Astrophysics All-Sky Survey Mission Concept

    Science.gov (United States)

    Miller, R. S.; Bonamente, M.; Burgess, J. M.; Harmon, B. A.; Jenke, P.; Lawrence, D. J.; O'Brien, S.; Orr, M. R.; Paciesas, W. S.; Young, C. A.

    2008-07-01

    The Lunar Occultation Observer (LOCO) is a new lunar-based concept to probe the nuclear astrophysics regime. It will be a pioneering mission in high-energy astrophysics: the first to employ occultation as the principle detection and imaging method.

  12. "In Loco Emporium": Immigrant Youth and Educators in the Social Contracts of Education

    Science.gov (United States)

    Patel, Lisa

    2013-01-01

    For adults training to be professional educators, the phrase, "in loco parentis," communicates the intention that schools and educators are meant to act in the role of the parent, commonly interpreted to mean acting in accordance with what is optimal for the development of the child or young person. The limits of this relationship have…

  13. Delictual Negligence of Educators in Schools: The Confusing Influence of the "in loco parentis" Doctrine

    Science.gov (United States)

    Potgieter, Johan

    2004-01-01

    This article points out that the "in loco parentis" maxim is partly to blame for introducing the confusing "reasonable parent" doctrine as the test for delictual negligence of educators in the school context. It is argued that the standard of care exercised by parents over their children is not appropriate to determine the negligence of educators.…

  14. In Loco Parentis Reinventis: Is There Still a Parenting Function in Higher Education?

    Science.gov (United States)

    Gregory, Dennis E.; Ballou, Roger A.

    1986-01-01

    Traces the history of the term in loco parentis, its decreased utility in the 1960s, and its recent evolution in different and more subtle ways. Supports the view that colleges are still very involved in acting as surrogate parents for their students. (Author/ABB)

  15. Frontiers in Planar Lightwave Circuit Technology Design, Simulation, and Fabrication

    CERN Document Server

    Janz, Siegfried; Tanev, Stoyan

    2005-01-01

    This book is the result of the NATO Advanced Research Workshop on Frontiers in Planar Lightwave Circuit Technology, which took place in Ottawa, Canada from September 21-25, 2004. Many of the world’s leading experts in integrated photonic design, theory and experiment were invited to give lectures in their fields of expertise, and participate in discussions on current research and applications, as well as the new directions planar lightwave circuit technology is evolving towards. The sum of their contributions to this book constitutes an excellent record of many key issues and scientific problems in planar lightwave circuit research at the time of writing. In this volume the reader will find detailed overviews of experimental and theoretical work in high index contrast waveguide systems, micro-optical resonators, nonlinear optics, and advanced optical simulation methods, as well as articles describing emerging applications of integrated optics for medical and biological applications.

  16. Loco-regional treatment in metastatic breast cancer patients: is there a survival benefit?

    Science.gov (United States)

    Ly, Bevan H; Nguyen, Nam P; Vinh-Hung, Vincent; Rapiti, Elisabetta; Vlastos, Georges

    2010-02-01

    A number of studies have recently demonstrated a survival benefit in stage IV breast cancer patients following surgical resection of the primary tumor. Here, we investigate the relationship between loco-regional treatment and survival in patients with metastatic breast cancer and evaluate the impact of different loco-regional treatments. We conducted a systematic review of the literature using PubMed to analyze studies with the following criteria: Type of loco-regional treatment (surgery alone or combined with radiation, radiotherapy), overall survival, progression-free survival, selection factors for local treatment, and complication rates. Thirteen studies evaluated the effect of loco-regional treatment on overall survival with overall median survival increasing from a range of 12.6-28.3 months among patients without surgery to a range of 25-42 months among patients with surgery. In addition, six studies reported a 3-year survival benefit of 28-95% and 17-79% in women with and without locoregional therapy respectively. Two studies did not find any improvement in overall survival. One study found an improvement in 5-year breast cancer-specific survival of 27% with negative surgical margins versus 12% with no surgery. Three studies reported an advantage in progression-free survival in the treatment group compared with the non-treatment group. Loco-regional treatment for breast cancer patients with distant metastases at diagnosis is an important issue because of possible improvement of survival or disease-free survival. The possibility of surgery and/or radiotherapy following induction chemotherapy should be weighed and left to individual practice. Participation in randomized controlled trials should be encouraged.

  17. Enabling cutting-edge semiconductor simulation through grid technology.

    Science.gov (United States)

    Reid, Dave; Millar, Campbell; Roy, Scott; Roy, Gareth; Sinnott, Richard; Stewart, Gordon; Stewart, Graeme; Asenov, Asen

    2009-06-28

    The progressive scaling of complementary metal oxide semiconductor (CMOS) transistors drives the success of the global semiconductor industry. Detailed knowledge of transistor behaviour is necessary to overcome the many fundamental challenges faced by chip and systems designers. Grid technology has enabled the unavoidable statistical variations introduced by scaling to be examined in unprecedented detail. Over 200 000 transistors have been simulated, the results of which provide detailed insight into underlying physical processes. This paper outlines recent scientific results of the nanoCMOS project and describes the way in which the scientific goals have been reflected in the grid-based e-Infrastructure.

  18. Modelling and Simulation of RF Multilayer Inductors in LTCC Technology

    Directory of Open Access Journals (Sweden)

    A. Čelić

    2009-11-01

    Full Text Available This paper is aimed at presenting the models and characteristics of two types of inductors designed in LTCC (Low Temperature Cofired Ceramic technology. We present the physical model of a 3D planar solenoid-type inductor and of a serial planar solenoid-type inductor for the RF (radio frequency range. To verify the results obtained by using these models, we have compared them with the results obtained by employing the Ansoft HFSS electromagnetic simulator. Very good agreement has been recorded for the effective inductance value, whereas the effective Q factor value has shown a somewhat larger deviation than the inductance.

  19. Helicopter Evacuation Following a Rural Trauma: An Emergency Medicine Simulation Scenario Using Innovative Simulation Technology.

    Science.gov (United States)

    Whalen, Desmond; Harty, Chris; Ravalia, Mohamed; Renouf, Tia; Alani, Sabrina; Brown, Robert; Dubrowski, Adam

    2016-03-08

    The relevance of simulation as a teaching tool for medical professionals working in rural and remote contexts is apparent when low-frequency, high-risk situations are considered. Simulation training has been shown to enhance learning and improve patient outcomes in urban settings. However, there are few simulation scenarios designed to teach rural trauma management during complex medical transportation. In this technical report, we present a scenario using a medevac helicopter (Replica of Sikorsky S-92 designed by Virtual Marine Technology, St. John's, NL) at a rural community. This case can be used for training primary care physicians who are working in a rural or remote setting, or as an innovative addition to emergency medicine and pre-hospital care training programs.

  20. POSTCOLONIALIDAD Y DESCOLONIALIDAD EN LOCO AFÁN: CRÓNICAS DE SIDARIO DE PEDRO LEMEBEL Postcolonialism and Decolonialism in Pedro Lemebel’s Loco Afán: Crónicas de Sidario

    Directory of Open Access Journals (Sweden)

    Jorge Lagos Caamaño

    2011-12-01

    Full Text Available Este trabajo tiene como propósito fundamental evidenciar la presencia de algunos rasgos del pensamiento postcolonial y descolonial en Loco afán. Crónicas de sidario de Pedro Lemebel.The fundamental purpose of the present work is to evidence the presence of some features of postcolonial and decolonial thought in Pedro Lemebel’s Loco Afán. Crónicas de Sidario.

  1. Simulation Technology Laboratory Building 970 hazards assessment document

    Energy Technology Data Exchange (ETDEWEB)

    Wood, C.L.; Starr, M.D.

    1994-11-01

    The Department of Energy Order 5500.3A requires facility-specific hazards assessments be prepared, maintained, and used for emergency planning purposes. This hazards assessment document describes the chemical and radiological hazards associated with the Simulation Technology Laboratory, Building 970. The entire inventory was screened according to the potential airborne impact to onsite and offsite individuals. The air dispersion model, ALOHA, estimated pollutant concentrations downwind from the source of a release, taking into consideration the toxicological and physical characteristics of the release site, the atmospheric conditions, and the circumstances of the release. The greatest distances at which a postulated facility event will produce consequences exceeding the ERPG-2 and Early Severe Health Effects thresholds are 78 and 46 meters, respectively. The highest emergency classification is a Site Area Emergency. The Emergency Planning Zone is 100 meters.

  2. Pattern of loco-regional failure after definitive radiotherapy for non-small cell lung cancer

    DEFF Research Database (Denmark)

    Schytte, Tine; Nielsen, Tine Bjørn; Brink, Carsten

    2014-01-01

    , and occurrence of distant metastasis. It is challenging to evaluate loco-regional control after definitive radiotherapy for NSCLC since it is difficult to distinguish between radiation-induced damage to the lung tissue and tumour progression/recurrence. In addition it may be useful to distinguish between...... intrapulmonary failure and mediastinal failure to be able to optimize radiotherapy in order to improve loco-regional control even though it is not easy to discriminate between the two sites of failure. Material and methods. This study is a retrospective analysis of 331 NSCLC patients treated with definitive...... with mediastinal relapse. Conclusion. We conclude that focus should be on increasing doses to intrapulmonary tumour volume, when dose escalation is applied to improve local tumour control in NSCLC patients treated with definitive radiotherapy, since most recurrences are located here....

  3. An overview of loco-regional treatments in patients and mouse models for hepatocellular carcinoma.

    Science.gov (United States)

    Bimonte, Sabrina; Barbieri, Antonio; Palaia, Raffaele; Leongito, Maddalena; Albino, Vittorio; Piccirillo, Mauro; Arra, Claudio; Izzo, Francesco

    2015-01-01

    Hepatocellular carcinoma is a highly aggressive malignancy and is the third leading cause of cancer-related deaths worldwide. Although surgery is currently considered the most effective curative treatment for this type of cancer, it is note that most of patients have a poor prognosis due to chemioresistence and tumor recurrence. Loco-regional therapies, including radiofrequency ablation, surgical resection and transcatheter arterial chemoembolization play a major role in the clinical management of hepatocellular carcinoma. In order to improve the treatment outcome of patients diagnosed with this disease, several in vivo studies by using different techniques on cancer mouse models have been performed. This review will focus on the latest papers on the efficacy of loco-regional therapy and combined treatments in patients and mouse models of hepatocellular carcinoma.

  4. Correction of Magnetic Optics and Beam Trajectory Using LOCO Based Algorithm with Expanded Experimental Data Sets

    Energy Technology Data Exchange (ETDEWEB)

    Romanov, A.; Edstrom, D.; Emanov, F. A.; Koop, I. A.; Perevedentsev, E. A.; Rogovsky, Yu. A.; Shwartz, D. B.; Valishev, A.

    2017-03-28

    Precise beam based measurement and correction of magnetic optics is essential for the successful operation of accelerators. The LOCO algorithm is a proven and reliable tool, which in some situations can be improved by using a broader class of experimental data. The standard data sets for LOCO include the closed orbit responses to dipole corrector variation, dispersion, and betatron tunes. This paper discusses the benefits from augmenting the data with four additional classes of experimental data: the beam shape measured with beam profile monitors; responses of closed orbit bumps to focusing field variations; betatron tune responses to focusing field variations; BPM-to-BPM betatron phase advances and beta functions in BPMs from turn-by-turn coordinates of kicked beam. All of the described features were implemented in the Sixdsimulation software that was used to correct the optics of the VEPP-2000 collider, the VEPP-5 injector booster ring, and the FAST linac.

  5. Radiofrequency Ablation to Treat Loco-Regional Recurrence of Well-Differentiated Thyroid Carcinoma

    OpenAIRE

    Lee, Sun Jin; Jung, So Lyung; Kim, Bum Soo; Ahn, Kook Jin; Choi, Hyun Seok; Lim, Dong Jun; Kim, Min Hee; Bae, Ja Seong; Kim, Min Sik; Jung, Chan Kwon; Chong, Se Min

    2014-01-01

    Objective To evaluate the efficacy of radiofrequency ablation (RFA) in the treatment of loco-regional, recurrent, and well-differentiated thyroid carcinoma. Materials and Methods Thirty-five recurrent well-differentiated thyroid carcinomas (RTC) in 32 patients were treated with RFA, between March 2008 and October 2011. RTCs were detected by regular follow-up ultrasound and confirmed by biopsy. All patients had fewer than 3 RTCs in the neck and were at high surgical risk or refused to undergo ...

  6. Prognostic Factors for Local, Loco-regional and Systemic Recurrence in Early-stage Breast Cancer.

    Science.gov (United States)

    Kümmel, A; Kümmel, S; Barinoff, J; Heitz, F; Holtschmidt, J; Weikel, W; Lorenz-Salehi, F; du Bois, A; Harter, P; Traut, A; Blohmer, J U; Ataseven, B

    2015-07-01

    Aim: The risk of recurrence in breast cancer depends on factors such as treatment but also on the intrinsic subtype. We analyzed the risk factors for local, loco-regional and systemic recurrence, evaluated the differences and analyzed the risk of recurrence for different molecular subtypes. Material and Methods: A total of 3054 breast cancer patients who underwent surgery followed by adjuvant treatment at HSK hospital or Essen Mitte Hospital between 1998 and 2011 were analyzed. Based on immunohistochemical parameters, cancers were divided into the following subgroups: luminal A, luminal B (HER2-), luminal B (HER2+), HER2+ and TNBC (triple negative breast cancer). Results: 67 % of tumors were classified as luminal A, 13 % as luminal B (HER2-), 6 % as luminal B (HER2+), 3 % as HER2+ and 11 % as TNBC. After a median follow-up time of 6.6 years there were 100 local (3.3 %), 32 loco-regional (1 %) and 248 distant recurrences (8 %). Five-year recurrence-free survival for the overall patient collective was 92 %. On multivariate analysis, positive nodal status, TNBC subtype and absence of radiation therapy were found to be independent risk factors for all forms of recurrence. Age loco-regional recurrence was low. In addition to nodal status, subgroup classification was found to be an important factor affecting the risk of recurrence.

  7. Personalization of loco-regional care for primary breast cancer patients (part 1).

    Science.gov (United States)

    Toi, Masakazu; Winer, Eric P; Benson, John R; Inamoto, Takashi; Forbes, John F; von Minckwitz, Gunter; Robertson, John F R; Grobmyer, Stephen R; Jatoi, Ismail; Sasano, Hironobu; Kunkler, Ian; Ho, Alice Y; Yamauchi, Chikako; Chow, Louis W C; Huang, Chiun-Sheng; Han, Wonshik; Noguchi, Shinzaburo; Pegram, Mark D; Yamauchi, Hideko; Lee, Eun-Sook; Larionov, Alexey A; Bevilacqua, Jose L B; Yoshimura, Michio; Sugie, Tomoharu; Yamauchi, Akira; Krop, Ian E; Noh, Dong Young; Klimberg, V Suzanne

    2015-01-01

    ABSTRACT  Kyoto Breast Cancer Consensus Conference, Kyoto, Japan, 18-20 February 2014 The loco-regional management of breast cancer is increasingly complex with application of primary systemic therapies, oncoplastic techniques and genetic testing for breast cancer susceptibility. Personalization of loco-regional treatment is integral to optimization of breast cancer care. Clinical and pathological tumor stage, biological features and host factors influence loco-regional treatment strategies and extent of surgical procedures. Key issues including axillary staging, axillary treatment, radiation therapy, primary systemic therapy (PST), preoperative hormonal therapy and genetic predisposition were identified and discussed at the Kyoto Breast Cancer Consensus Conference (KBCCC2014). In the first of a two part conference scene, consensus recommendations for axillary management are presented and focus on the following topics: indications for completion axillary lymph node dissection in primary surgical patients with ≤2 macrometastases or any sentinel nodal deposits after PST; the timing of sentinel lymph node biopsy in the context of PST; use of axillary irradiation as a component of primary treatment plans and the role of intraoperative node assessment in the post-Z0011 era.

  8. Personalization of loco-regional care for primary breast cancer patients (part 2).

    Science.gov (United States)

    Toi, Masakazu; Winer, Eric P; Benson, John R; Inamoto, Takashi; Forbes, John F; von Minckwitz, Gunter; Robertson, John F R; Grobmyer, Stephen R; Jatoi, Ismail; Sasano, Hironobu; Kunkler, Ian; Ho, Alice Y; Yamauchi, Chikako; Chow, Louis W C; Huang, Chiun-Sheng; Han, Wonshik; Noguchi, Shinzaburo; Pegram, Mark D; Yamauchi, Hideko; Lee, Eun-Sook; Larionov, Alexey A; Bevilacqua, Jose L B; Yoshimura, Michio; Sugie, Tomoharu; Yamauchi, Akira; Krop, Ian E; Noh, Dong Young; Klimberg, V Suzanne

    2015-01-01

    Kyoto Breast Cancer Consensus Conference, Kyoto, Japan, 18-20 February 2014 The loco-regional management of breast cancer is increasingly complex with application of primary systemic therapies, oncoplastic techniques and genetic testing for breast cancer susceptibility. Personalization of loco-regional treatment is integral to optimization of breast cancer care. Clinical and pathological tumor stage, biological features and host factors influence loco-regional treatment strategies and extent of surgical procedures. Key issues including axillary staging, axillary treatment, radiation therapy, primary systemic therapy (PST), preoperative hormonal therapy and genetic predisposition were identified and discussed at the Kyoto Breast Cancer Consensus Conference (KBCCC2014). In the second of a two part conference scene, consensus recommendations for radiation treatment, primary systemic therapies and management of genetic predisposition are reported and focus on the following topics: influence of both clinical response to PST and stage at presentation on recommendations for postmastectomy radiotherapy; use of regional nodal irradiation in selected node-positive patients and those with adverse pathological factors; extent of surgical resection following downstaging of tumors with PST; use of preoperative hormonal therapy in premenopausal women with larger, node-negative luminal A-like tumors and managing increasing demands for contralateral prophylactic mastectomy in patients with a unilateral sporadic breast cancer.

  9. Fine mapping of the chicken congenital loco locus on chromosome 12.

    Science.gov (United States)

    Okumura, Y; Ohtake, T; Uemoto, Y; Sato, S; Sato, S; Kobayashi, E

    2013-12-01

    Congenital loco in chicks is characterized by an apparent lack of control of the muscles of the neck. This disorder is inherited as a simple Mendelian recessive disease, caused by an autosomal recessive gene, lo. To date, there are no reports on the localization of this gene. The objective of this study was therefore to identify the genomic region of the lo locus. The experimental congenital loco population used here were selected from a Rhode Island Red (RIR) line and consisted of six generations, resulting in 124 chickens. A total of 113 DNA samples from offspring of four generations (G3, G4, G5, and G6) were used for genotyping. At first, genome-wide linkage mapping was performed using 122 microsatellite markers on 22 autosomal chromosomes, and the lo locus was mapped to chromosome 12. We then performed fine mapping in two steps on chromosome 12. First, the lo locus was mapped to the interval between GGA12_5 and GGA12_11 using 13 new polymorphic markers. In the second step, fine mapping was performed by adding new families and 11 additional new polymorphic markers. Linkage mapping and haplotype information enabled the localization of the lo locus to a 1.1-Mb region between GGA12_28 and GGA12_30. Genetic markers between GGA12_28 and GGA12_30 may be used to remove the carriers of congenital loco through this RIR line.

  10. Comparing Productivity Simulated with Inventory Data Using Different Modelling Technologies

    Science.gov (United States)

    Klopf, M.; Pietsch, S. A.; Hasenauer, H.

    2009-04-01

    The Lime Stone National Park in Austria was established in 1997 to protect sensible lime stone soils from degradation due to heavy forest management. Since 1997 the management activities were successively reduced and standing volume and coarse woody debris (CWD) increased and degraded soils began to recover. One option to study the rehabilitation process towards natural virgin forest state is the use of modelling technology. In this study we will test two different modelling approaches for their applicability to Lime Stone National Park. We will compare standing tree volume simulated resulting from (i) the individual tree growth model MOSES, and (ii) the species and management sensitive adaptation of the biogeochemical-mechanistic model Biome-BGC. The results from the two models are compared with filed observations form repeated permanent forest inventory plots of the Lime Stone National Park in Austria. The simulated CWD predictions of the BGC-model were compared with dead wood measurements (standing and lying dead wood) recorded at the permanent inventory plots. The inventory was established between 1994 and 1996 and remeasured from 2004 to 2005. For this analysis 40 plots of this inventory were selected which comprise the required dead wood components and are dominated by a single tree species. First we used the distance dependant individual tree growth model MOSES to derive the standing timber and the amount of mortality per hectare. MOSES is initialized with the inventory data at plot establishment and each sampling plot is treated as forest stand. The Biome-BGC is a process based biogeochemical model with extensions for Austrian tree species, a self initialization and a forest management tool. The initialization for the actual simulations with the BGC model was done as follows: We first used spin up runs to derive a balanced forest vegetation, similar to an undisturbed forest. Next we considered the management history of the past centuries (heavy clear cuts

  11. Simulated experiments with complex sustainable systems. Ecology and technology

    Energy Technology Data Exchange (ETDEWEB)

    Cabezas, Heriberto; Pawlowski, Christopher W.; Mayer, Audrey L.; Hoagland, N. Theresa [U.S. Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Sustainable Technology Division, Sustainable Environments Branch, 26 West Martin Luther King Drive, MS 498, Cincinnati, OH 45268 (United States)

    2005-06-15

    The concept of sustainability is associated with the statement from the World Commission on Environment and Development, 1987: '...development that meets the needs and aspirations of the present without compromising the ability to meet those of the future...' However, this statement lacks a practical environmental management strategy. The goal of a sustainable management strategy is to promote the structure and operation of the human component of a system (society, economy, technology, etc.) in such a manner as to reinforce the persistence of the structures and operation of the natural component (i.e., the ecosystem). We report on our efforts to identify the characteristics of sustainable systems with a simulation model that comprises an ecological food web and a simple, abstract industrial sector. We consider three different industry types, each taking different combinations of inputs from agriculture, natural resource extraction and harvesting of a wild animal species. We explore several scenarios including halving industrial efficiency, doubling the throughput of the industrial process (IP), and doubling the wastefulness of production. We present the results with the aid of a summary measure based on information theory.

  12. Computer simulation of an advanced combustor for clean coal technology

    Energy Technology Data Exchange (ETDEWEB)

    Chang, S.L.; Lottes, S.A.

    1992-01-01

    Magnetohydrodynamic (MHD) power generation is a clean coal technology because of its higher thermal efficiency and lower pollutant emission. Argonne National Laboratory used a comprehensive integral combustion computer code to aid the development of a TRW's second stage combustor for MHD power generation. The integral combustion code is a computer code for two-phase, two-dimensional, steady state, turbulent, and reacting flows, based on mass, momentum, and energy conservation laws for multiple gas species and solid particles of variable sizes. In the MHD second stage combustor, opposed jets of oxidizer are injected into a confined cross-stream coal gas flow laden with seed particles. The performance of the downstream MHD power generation channel depends mainly on the degree and the uniformity of gas ionization, which, in turn, depends on the uniformity of temperature and seed vapor distributions leaving the combustor. The simulation provides in-depth information of flow, combustion, and heat transfer patterns in the combustor, which is used to predict ranges of combustor operating conditions for optimum performance of the MHD system.

  13. Computer simulation of an advanced combustor for clean coal technology

    Energy Technology Data Exchange (ETDEWEB)

    Chang, S.L.; Lottes, S.A.

    1992-09-01

    Magnetohydrodynamic (MHD) power generation is a clean coal technology because of its higher thermal efficiency and lower pollutant emission. Argonne National Laboratory used a comprehensive integral combustion computer code to aid the development of a TRW`s second stage combustor for MHD power generation. The integral combustion code is a computer code for two-phase, two-dimensional, steady state, turbulent, and reacting flows, based on mass, momentum, and energy conservation laws for multiple gas species and solid particles of variable sizes. In the MHD second stage combustor, opposed jets of oxidizer are injected into a confined cross-stream coal gas flow laden with seed particles. The performance of the downstream MHD power generation channel depends mainly on the degree and the uniformity of gas ionization, which, in turn, depends on the uniformity of temperature and seed vapor distributions leaving the combustor. The simulation provides in-depth information of flow, combustion, and heat transfer patterns in the combustor, which is used to predict ranges of combustor operating conditions for optimum performance of the MHD system.

  14. Judicious Use of Simulation Technology in Continuing Medical Education

    Science.gov (United States)

    Curtis, Michael T.; DiazGranados, Deborah; Feldman, Moshe

    2012-01-01

    Use of simulation-based training is fast becoming a vital source of experiential learning in medical education. Although simulation is a common tool for undergraduate and graduate medical education curricula, the utilization of simulation in continuing medical education (CME) is still an area of growth. As more CME programs turn to simulation to…

  15. Why simulation can be efficient: on the preconditions of efficient learning in complex technology based practices

    Directory of Open Access Journals (Sweden)

    Hofmann Bjørn

    2009-07-01

    Full Text Available Abstract Background It is important to demonstrate learning outcomes of simulation in technology based practices, such as in advanced health care. Although many studies show skills improvement and self-reported change to practice, there are few studies demonstrating patient outcome and societal efficiency. The objective of the study is to investigate if and why simulation can be effective and efficient in a hi-tech health care setting. This is important in order to decide whether and how to design simulation scenarios and outcome studies. Methods Core theoretical insights in Science and Technology Studies (STS are applied to analyze the field of simulation in hi-tech health care education. In particular, a process-oriented framework where technology is characterized by its devices, methods and its organizational setting is applied. Results The analysis shows how advanced simulation can address core characteristics of technology beyond the knowledge of technology's functions. Simulation's ability to address skilful device handling as well as purposive aspects of technology provides a potential for effective and efficient learning. However, as technology is also constituted by organizational aspects, such as technology status, disease status, and resource constraints, the success of simulation depends on whether these aspects can be integrated in the simulation setting as well. This represents a challenge for future development of simulation and for demonstrating its effectiveness and efficiency. Conclusion Assessing the outcome of simulation in education in hi-tech health care settings is worthwhile if core characteristics of medical technology are addressed. This challenges the traditional technical versus non-technical divide in simulation, as organizational aspects appear to be part of technology's core characteristics.

  16. Teaching Engineering Statistics with Technology, Group Learning, Contextual Projects, Simulation Models and Student Presentations

    Science.gov (United States)

    Romeu, Jorge Luis

    2008-01-01

    This article discusses our teaching approach in graduate level Engineering Statistics. It is based on the use of modern technology, learning groups, contextual projects, simulation models, and statistical and simulation software to entice student motivation. The use of technology to facilitate group projects and presentations, and to generate,…

  17. Computer simulation and optimal designing of energy-saving technologies of the induction heating of metals

    Science.gov (United States)

    Demidovich, V. B.

    2012-12-01

    Advanced energy-saving technologies of induction heating of metals are discussed. The importance of the joint simulation of electromagnetic and temperature fields on induction heating is demonstrated. The package of specialized programs for simulating not only induction heating devices, but also technologies that employ industrial heating has been developed. An intimate connection between optimal design and control of induction heaters is shown.

  18. Using Monte Carlo Simulation Technology to Improve Intuitive Effect of Teaching Probability and Mathematical Statistics Course

    Institute of Scientific and Technical Information of China (English)

    万文应; 夏庆

    2015-01-01

    With the illustration of a specific problem, this paper demonstrates that using Monte Carlo Simulation technology will improve intuitive effect of teaching Probability and Mathematical Statistics course, and save instructors’ effort as well.And it is estimated that Monte Carlo Simulation technology will be one of the major teaching methods for Probability and Mathematical Statistics course in the future.

  19. Teaching Engineering Statistics with Technology, Group Learning, Contextual Projects, Simulation Models and Student Presentations

    Science.gov (United States)

    Romeu, Jorge Luis

    2008-01-01

    This article discusses our teaching approach in graduate level Engineering Statistics. It is based on the use of modern technology, learning groups, contextual projects, simulation models, and statistical and simulation software to entice student motivation. The use of technology to facilitate group projects and presentations, and to generate,…

  20. Image Compression Ratio Control Based on LOCO-Ⅰ Algorithm%基于LOCO-Ⅰ算法的图像压缩比控制

    Institute of Scientific and Technical Information of China (English)

    陈益刚; 邓家先; 谢凯明

    2015-01-01

    在认真研究LOCO-Ⅰ算法的基础上,深入分析了失真控制参数Near对图像压缩比和重建质量的影响,通过对该算法中的Near进行实时动态调整,实现了对图像近无损压缩的压缩比控制,进而可以根据需求来控制图片大小进行压缩.仿真结果表明,提出的压缩比控制方案收敛性较好,输出码流稳定,在满足目标压缩比时重建图像质量较原一阶压缩比控制方案提高了0.5 dB左右.

  1. 7th Conference Simulation and Testing for Vehicle Technology

    CERN Document Server

    Riese, Jens; Rüden, Klaus

    2016-01-01

    The book includes contributions on the latest model-based methods for the development of personal and commercial vehicle control devices. The main topics treated are: application of simulation and model design to development of driver assistance systems; physical and database model design for engines, motors, powertrain, undercarriage and the whole vehicle; new simulation tools, methods and optimization processes; applications of simulation in function and software development; function and software testing using HiL, MiL and SiL simulation; application of simulation and optimization in application of control devices; automation approaches at all stages of the development process.

  2. Piloting Augmented Reality Technology to Enhance Realism in Clinical Simulation.

    Science.gov (United States)

    Vaughn, Jacqueline; Lister, Michael; Shaw, Ryan J

    2016-09-01

    We describe a pilot study that incorporated an innovative hybrid simulation designed to increase the perception of realism in a high-fidelity simulation. Prelicensure students (N = 12) cared for a manikin in a simulation lab scenario wearing Google Glass, a wearable head device that projected video into the students' field of vision. Students reported that the simulation gave them confidence that they were developing skills and knowledge to perform necessary tasks in a clinical setting and that they met the learning objectives of the simulation. The video combined visual images and cues seen in a real patient and created a sense of realism the manikin alone could not provide.

  3. Simulator Technology of the Gravity Probe-B Mission

    Science.gov (United States)

    Hipkins, David; Brumley, Robert; Ohshima, Yoshimi; Holmes, Thomas

    2007-04-01

    The Gravity Probe B mission relied on simulators extensively both in the development and operational phases. They played a critical role in the mission's overall success. The primary simulator was the Integrated Test Facility (ITF) built by Lockheed-Martin. This simulator was assembled to provide spacecraft dynamics simulation as well as flight software validation and verification. There were also subsystem simulators that played equally important roles. The gyroscope suspension system team developed and built a hardware-in-the-loop gyroscope simulator designed to be able to operate over 10 orders of magnitude in force domain. This simulator evolved during on-orbit operations into a state of the art drag-free simulator. Simulated sensors for the SQUID readout system, telescope readout system and even an artificial star to test the performance of the telescope optics were used extensively for qualification tests prior to launch. One of the more important lessons learned is for missions where the spacecraft to payload coupling becomes the greatest challenge, simulators of the future need to be designed with coupled interfaces and these simulators must be employed early in the design and build phase of the mission.

  4. Simulation technologies in networking and communications selecting the best tool for the test

    CERN Document Server

    Pathan, Al-Sakib Khan; Khan, Shafiullah

    2014-01-01

    Simulation is a widely used mechanism for validating the theoretical models of networking and communication systems. Although the claims made based on simulations are considered to be reliable, how reliable they really are is best determined with real-world implementation trials.Simulation Technologies in Networking and Communications: Selecting the Best Tool for the Test addresses the spectrum of issues regarding the different mechanisms related to simulation technologies in networking and communications fields. Focusing on the practice of simulation testing instead of the theory, it presents

  5. Loco-regional cancer drug therapy: present approaches and rapidly reversible hydrophobization (RRH) of therapeutic agents as the future direction.

    Science.gov (United States)

    Budker, Vladimir G; Monahan, Sean D; Subbotin, Vladimir M

    2014-12-01

    Insufficient drug uptake by solid tumors remains the major problem for systemic chemotherapy. Many studies have demonstrated anticancer drug effects to be dose-dependent, although dose-escalation studies have resulted in limited survival benefit with increased systemic toxicities. One solution to this has been the idea of loco-regional drug treatments, which offer dramatically higher drug concentrations in tumor tissues while minimizing systemic toxicity. Although loco-regional delivery has been most prominent in cancers of the liver, soft tissues and serosal peritoneal malignancies, survival benefits are very far from desirable. This review discusses the evolution of loco-regional treatments, the present approaches and offers rapidly reversible hydrophobization of drugs as the new future direction.

  6. Simulate a ‘Sun’ for Solar Research : A Literature Review of Solar Simulator Technology

    OpenAIRE

    Wang, Wujun; Laumert, Björn

    2014-01-01

    The solar simulator is the key facility for indoor research of solar PV cells, solar heat collectors, space craft and CSP systems. This paper classifies the four types of solar simulators based on their characteristics and their design objects: space solar simulator, standard PV cell testing solar simulator, collector testing solar simulator and high-flux solar simulator. The review of solar simulator developments is mainly based on the developments of light sources and optical concentrators....

  7. Use of Virtual Environment Training Technology for Individual Combat Simulation

    Science.gov (United States)

    1993-02-01

    the same training environments as Level 3 display technology (except 31 that use of a HMD does not necessarily require the use of Level 3 haptic sensing...through limits on the allowable movement speed Finally, Level 3 technology improves upon (or augments ) Level 2 through: High-resolution HMD Measurement...of eye position if required by the high-resolution HMD Advanced speech recognition technology Programmable general-purpose haptic interfaces (e.g

  8. Development of the fabrication technology of the simulated DUPIC fuel

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Kweon Ho; Yang, M. S.; Bae, K. K. and others

    2000-06-01

    It is important to get basic data to analysis physical properties, behavior in reactor and performance of the DUPIC fuel because physical properties of the DUPIC fuel is different from the commercial UO{sub 2} fuel. But what directly measures physical properties et al. of DUPIC fuel being resinterred simulated spent fuel through OREOX process is very difficult in laboratory owing to its high level radiation. Then fabrication of simulated DUPIC fuel is needed to measure its properties. In this study, processes on powder treatment, OREOX, compaction and sintering to fabricate simulated DUPIC fuel using simulated spent fuel are discribed. To fabricate simulated DUPIC fuel, the powder from 3 times OREOX and 5 times attrition milling simulated spent fuel is compacted with 1.3 ton/cm{sup 2}. Pellets are sintered in 100% H{sub 2} atmosphere over 10 h at 1800 deg C. Sintered densities of pellets are 10.2-10.5 g/cm{sup 3}.

  9. Utilizing a Simulation within an Online School Technology Leadership Course

    Science.gov (United States)

    Strycker, Jesse

    2016-01-01

    Online courses and programs have grown to become and continue to be a popular option for students. As part of an online Master's of Education in Instructional Technology program, students must complete a school technology leadership course. Leadership decision making, policy making, and how to have innovations take hold in a school settings are…

  10. Learning in Technology-Enhanced Medical Simulation: Locations and Knowings

    Directory of Open Access Journals (Sweden)

    Song-ee Ahn

    2015-06-01

    Full Text Available This qualitative study focuses on how knowings and learning take place in full-scale simulation training of medical and nursing students, by drawing upon actor-network theory (ANT. ANT situates materiality as a part of the social practices. Knowing and learning, according to ANT, are not simply cognitive or social phenomena, but are seen as emerging as effects of the relation between material assemblages and human actors being performed into being in particular locations. Data consists of observations of simulations performed by ten groups of students. The analysis focuses on the emerging knowings in the socio-material—arrangements of three locations involved in the simulation—the simulation room, the observation room and the reflection room. The findings indicate that medical knowing, affective knowing and communicative knowing are produced in different ways in the different locations and material arrangements of the simulation cycle.Keywords: simulation, locations, knowings, actor-network theory, collaborate learning, multiprofessional learning.

  11. Gall bladder carcinoma: Aggressive malignancy with protean loco-regional and distant spread.

    Science.gov (United States)

    Dwivedi, Amit Nandan Dhar; Jain, Shivi; Dixit, Ruhi

    2015-03-16

    The most common malignancy of biliary tract is gallbladder cancer (GBC) which is the third most common cancer in gastrointestinal tract. It is a lethal disease for most patients in spite of growing awareness and improved diagnostic techniques. GBC has a very poor prognosis and the 5 year survival rate is loco-regional rather than distant. It spreads by lymphatic, vascular, neural, intraperitoneal, and intraductal routes. Sonography is usually the most common imaging test to evaluate symptoms of biliary tract disease including suspected GC. With recent advances in imaging modalities like multi-detector computed tomography (CT) scanners, magnetic resonance imaging-positron emission tomography/CT diagnosis of gallbladder cancer has improved. Studies have also targeted molecular and genetic pathways. Treatment options have included extended and radical surgeries and adjuvant chemotherapy. This review article deals in detail with important aspects of carcinoma gallbladder and its manifestations and challenges. Role of various imaging modalities in characterization and accurate staging has been discussed. The loco-regional spread of this aggressive malignancy is dealt explicitly.

  12. Treatment for isolated loco-regional recurrence of gastric adenocarcinoma: Does surgery play a role?

    Institute of Scientific and Technical Information of China (English)

    Fabio Carboni; Pasquale Lepiane; Roberto Santoro; Riccardo Lorusso; Pietro Mancini; Massimo Carlini; Eugenio Santoro

    2005-01-01

    AIM: To evaluate the role of surgical treatment for isolated loco-regional recurrences of operated gastric adenocarcinoma.METHODS: Among the 837 patients operated for gastric adenocarcinoma between December 1979and April 2004, 713 (85%) underwent resection with curative intent. A retrospective review of a prospectively collected gastric cancer database was carried out.Overall recurrence rate was 44% (315 cases), with 75%occurring within the first 2 years from the operation.Isolated L-R recurrences were observed in 38 (12%)patients. Symptomatic lesions were observed in 27(71%).RESULTS: Six (16%) patients were macroscopically resected with curative intent. The recurrence was located in the gastric stump after a STG in three patients, in theesophagojejunal anastomosis after a TG in two patients and in the gastric bed after a TG in one patient.Surgical procedures consisted of three secondary TG, two esophagojejunal resection and one excision of an extraluminal recurrence. Postoperative complications occurred in two patients (33%), including one anastomotic leakage and one hemorrhage. The latter patient died of sepsis 35 d after the surgery (mortality rate 17%). All patients died of recurrent gastric cancer:2 within 1 year from surgery (8 and 11 mo, respectively),2 after 16 and 17 mo respectively and 1 after 28 mo from the second operation.CONCLUSION: Surgery plays a very limited role in the treatment for isolated loco-regional recurrence of gastric adenocarcinoma.

  13. Alternative energy technologies an introduction with computer simulations

    CERN Document Server

    Buxton, Gavin

    2014-01-01

    Introduction to Alternative Energy SourcesGlobal WarmingPollutionSolar CellsWind PowerBiofuelsHydrogen Production and Fuel CellsIntroduction to Computer ModelingBrief History of Computer SimulationsMotivation and Applications of Computer ModelsUsing Spreadsheets for SimulationsTyping Equations into SpreadsheetsFunctions Available in SpreadsheetsRandom NumbersPlotting DataMacros and ScriptsInterpolation and ExtrapolationNumerical Integration and Diffe

  14. 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications

    CERN Document Server

    Koziel, Slawomir; Kacprzyk, Janusz; Leifsson, Leifur; Ören, Tuncer

    2015-01-01

    This book includes extended and revised versions of a set of selected papers from the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2013) which was co-organized by the Reykjavik University (RU) and sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC). SIMULTECH 2013 was held in cooperation with the ACM SIGSIM - Special Interest Group (SIG) on SImulation and Modeling (SIM), Movimento Italiano Modellazione e Simulazione (MIMOS) and AIS Special Interest Group on Modeling and Simulation (AIS SIGMAS) and technically co-sponsored by the Society for Modeling & Simulation International (SCS), Liophant Simulation, Simulation Team and International Federation for Information Processing (IFIP). This proceedings brings together researchers, engineers, applied mathematicians and practitioners working in the advances and applications in the field of system simulation.

  15. Science Technology Society Simulations: Engaging Students with Issues-based Scenarios.

    Science.gov (United States)

    Bodzin, Alec M.; Mamlok, Rachel

    2000-01-01

    Describes Science Technology and Society (STS) simulations that teach students about human experiences involving controversial issues. When students are taught using controversial and authentic issues, science instruction becomes current and engaging. (SAH)

  16. The Emergence of New Paradigms in Student-University Relations: From In Loco Parentis to Bystander to Facilitator.

    Science.gov (United States)

    Bickel, Robert D.; Lake, Peter F.

    1997-01-01

    University liability is in transition; its role changing from a parental/custodial "in loco parentis" model (and then a bystander role) to a new model of facilitator. The university enjoys a position of authority and respect, while exercising control more subtly than in the mid-1990s. At the same time, universities may be unable to claim the same…

  17. Lacuna in the Practice of In-Loco-Parentis in Nigerian Schools: The Pot Calling the Kettle Black

    Science.gov (United States)

    Igbinedion, Doye Angela; Nwogu, Uzoma Jonah; Abraham, Nath M.

    2016-01-01

    The principle of in-loco-parentis allows the teachers to assume the responsibilities of a parent in discharging their duties in school. Based on this same principle, parents also have the right to sue teachers, school management, or the government for negligence, recklessness and other practices which do not depict the proper practice of…

  18. Using virtual reality technology to include field operators in simulation and training

    Energy Technology Data Exchange (ETDEWEB)

    Nystad, E.; Strand, S. [OECD Halden Reactor Project (Norway)]. E-mail: espen.nystad@hrp.no

    2006-07-01

    By using virtual reality technology, field operators can be included in simulator training. A study has been performed where field operators could perform their activities in a virtual plant and communicate with a control room operator who was placed in a physical control room simulator. This paper describes the use of VR technology in the study and how the operators experienced interacting with the virtual plant. (author)

  19. Using of simulation for comparison of technologies for pallets storing

    Science.gov (United States)

    Kříž, Pavel; Chramcov, Bronislav; Jemelka, Milan

    2016-06-01

    The paper highlights the problem oftechnology for pallet storing. The aim is to compare selected technologies and to find efficient warehouse solution for the real company, which produces a plastic parts for automotive and needs to solve storing in the new hall. The work describes differences between two pallet storing technologies - static racking system and powered mobile racking system. Comparison contains description, advantages and disadvantages of the both systems. Real data from real project are used for the evaluation of necessary parameters. The result presents proposal of solution which can meet all initial conditions.

  20. Optimization of suspension smelting technology by computer simulation

    Energy Technology Data Exchange (ETDEWEB)

    Lilius, K.; Jokilaakso, A.; Ahokainen, T.; Teppo, O.; Yang Yongxiang [Helsinki Univ. of Technology, Otaniemi (Finland). Lab. of Materials Processing and Powder Metallurgy

    1994-12-31

    The flash smelting process has been extensively studied during its over 40 years existence. Laboratory or pilot scale experiments can not, however, predict all the complicated and coupled phenomena taking place in a flash smelting furnace. Development of commercial modelling software and increasingly efficient computers have brought a new tool to researchers for more comprehensive investigation of the transport and combustion processes taking place in the flash smelting process. A flash smelting furnace and a waste-heat boiler geometry have been simulated in two- and three-dimensional laboratory models which have, in turn, been modeled by using commercial Computational-Fluid-Dynamics -software. The computer simulation has then been extended to an industrial-scale furnace and waste-heat boiler. The work has proceeded from cold gas flow to heat transfer, combustion, and two-phase flow simulations. In the present approach, the modelling task has been divided into submodels. Outlet values of a model are used as inlet values in the subsequent submodel. Heat transfer calculations have been carried out starting from very basic considerations. Different options of the software and heat transfer modes have been tested, and hot gas flow through the furnace and boiler has been simulated. Validation of the models was carried out with temperature measurements from the uptake shaft. Also one geometrical variation of the uptake shaft has been simulated, namely turning the outlet of the shaft 90 degrees. Combustion of sulphides is approximated with gaseous combustion by using a built-in combustion model of the software. The waste-heat boiler has been simulated first as an empty geometry, and adding gradually approximated radiation curtains and convection tube bundles. Both convection and radiation heat transfer were considered. (orig.)

  1. Desktop Simulation: Towards a New Strategy for Arts Technology Education

    Science.gov (United States)

    Eidsheim, Nina Sun

    2009-01-01

    For arts departments in many institutions, technology education entails prohibitive equipment costs, maintenance requirements and administrative demands. There are also inherent pedagogical challenges: for example, recording studio classes where, due to space and time constraints, only a few students in what might be a large class can properly…

  2. What Can Students Learn in an Extended Role-Play Simulation on Technology and Society?

    Science.gov (United States)

    Loui, Michael C.

    2009-01-01

    In a small course on technology and society, students participated in an extended role-play simulation for two weeks. Each student played a different adult character in a fictional community, which faces technological decisions in three scenarios set in the near future. The three scenarios involved stem cell research, nanotechnology, and privacy.…

  3. Distinctions Between Computer Simulations and Other Technologies for Science Education

    DEFF Research Database (Denmark)

    Pfeffer, Melanie; Renken, Maggie; Girault, Isabelle

    2016-01-01

    We define simulations as algorithmic, dynamic, often simplified models of real-world or hypothetical phenomenon that contain features that not only allow but promote the exploration of ideas, manipulation of parameters, observation of events, and testing of questions. Many of the features in this...

  4. Visual Technology Research Simulator (VTRS) Human Performance Research: Phase III.

    Science.gov (United States)

    1981-11-01

    8217 Unclassi f ied 16 DISTRIBUTION STATEMENT .l, thi. Rop-o Approved for public release; distribution unlimited. 77 L31STRBUTION STATEMENT (oi I)h. obst ,&cl...and data collected during simulated carrier-landing trials on the ASPT at Williams Air Force Base, Arizona, and on the, VTRS at Orlando, Florida, are

  5. Simulation Tools for Power Electronics Courses Based on Java Technologies

    Science.gov (United States)

    Canesin, Carlos A.; Goncalves, Flavio A. S.; Sampaio, Leonardo P.

    2010-01-01

    This paper presents interactive power electronics educational tools. These interactive tools make use of the benefits of Java language to provide a dynamic and interactive approach to simulating steady-state ideal rectifiers (uncontrolled and controlled; single-phase and three-phase). Additionally, this paper discusses the development and use of…

  6. Simulation Tools for Power Electronics Courses Based on Java Technologies

    Science.gov (United States)

    Canesin, Carlos A.; Goncalves, Flavio A. S.; Sampaio, Leonardo P.

    2010-01-01

    This paper presents interactive power electronics educational tools. These interactive tools make use of the benefits of Java language to provide a dynamic and interactive approach to simulating steady-state ideal rectifiers (uncontrolled and controlled; single-phase and three-phase). Additionally, this paper discusses the development and use of…

  7. Designing a Virtual Olympic Games Framework by Using Simulation in Web 2.0 Technologies

    Science.gov (United States)

    Stoilescu, Dorian

    2013-01-01

    Instructional simulation had major difficulties in the past for offering limited possibilities in practice and learning. This article proposes a link between instructional simulation and Web 2.0 technologies. More exactly, I present the design of the Virtual Olympic Games Framework (VOGF), as a significant demonstration of how interactivity in…

  8. Optimization of suspension smelting technology by computer simulation

    Energy Technology Data Exchange (ETDEWEB)

    Lilius, K.; Jokilaakso, A.; Ahokainen, T.; Teppo, O.; Yang Yongxiang [Helsinki Univ. of Technology, Otaniemi (Finland). Lab. of Materials Processing and Powder Metallurgy

    1996-12-31

    An industrial-scale flash smelting furnace and waste-heat boilers have been modelled by using commercial Computational-Fluid-Dynamics software. The work has proceeded from cold gas flow to heat transfer, combustion, and two-phase flow simulations. In the present study, the modelling task has been divided into three sub-models: (1) the concentrate burner, (2) the flash smelting furnace (reaction shaft and uptake shaft), and (3) the waste-heat boiler. For the concentrate burner, the flow of the process gas and distribution air together with the concentrate or a feed mixture was simulated. Eulerian - Eulerian approach was used for the carrier gas-phase and the dispersed particle-phase. A large parametric study was carried out by simulating a laboratory scale burner with varying turbulence intensities and then extending the simulations to the industrial scale model. For the flash smelting furnace, the simulation work concentrated on gas and gas-particle two-phase flows, as well as the development of combustion model for sulphide concentrate particles. Both Eulerian and Lagrangian approaches have been utilised in describing the particle phase and the spreading of the concentrate in the reaction shaft as well as the particle tracks have been obtained. Combustion of sulphides was first approximated with gaseous combustion by using a built-in combustion model of the software. The real oxidation reactions of the concentrate particles were then coded as a user-defined sub-routine and that was tested with industrial flash smelting cases. For the waste-heat boiler, both flow and heat transfer calculations have been carried out for an old boiler and a modified boiler SULA 2 Research Programme; 23 refs.

  9. The Simulation of Grinding Wheels and Ground Surface Roughness Based on Virtual Reality Technology

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The paper describes the feasibility and method of the application of virtual reality technology to grinding process, and introduces the modeling method of object entity in the environment of virtual reality. The simulation process of grinding wheels and ground surface roughness is discussed, and the computation program system of numerical simulation is compiled with Visual C++ programming language. At the same time, the three-dimensional simulation models of grinding wheels and ground surface roughness are ...

  10. Manufacturing Resource Planning Technology Based on Genetic Programming Simulation

    Institute of Scientific and Technical Information of China (English)

    GAO Shiwen; LIAO Wenhe; GUO Yu; LIU Jinshan; SU Yan

    2009-01-01

    Network-based manufacturing is a kind of distributed system, which enables manufacturers to finish production tasks as well as to grasp the opportunities in the market, even if manufacturing resources are insufficient. One of the main problems in network-based manufacturing is the allocation of resources and the assignment of tasks rationally, according to flexible resource distribution. The mapping rules and relations between production techniques and resources are proposed, followed by the definition of the resource unit. Ultimately, the genetic programming method for the optimization of the manufacturing system is put forward. A set of software for the optimization system of simulation process using genetic programming techniques has been developed, and the problems of manufacturing resource planning in network-based manufacturing are solved with the simulation of optimizing methods by genetic programming. The optimum proposal of hardware planning, selection of company and scheduling will be obtained in theory to help company managers in scientific decision-making.

  11. Simulation Technologies for C2IS Development & Training

    Science.gov (United States)

    2008-02-01

    Electrical and Electronics Engineers (IEEE) 1516 est decrit de fa,on concise. L’ environnement de developpement d’ agents logiciels intelligents JACK...son essence consiste it distribuer la responsabilite de divers aspects de la simulation entre differentes entites logicielles . Ceci permet it la...des composants ameliores lorsqu’ils surviennent. Les developpeurs sont libres de specialiser leur modele, sachant que les "d6ficiences" que leur

  12. Simulating care: technology-mediated learning in twenty-first century nursing education.

    Science.gov (United States)

    Diener, Elizabeth; Hobbs, Nelda

    2012-01-01

    The increased reliance on simulation classrooms has proven successful in learning skills. Questions persist concerning the ability of technology-driven robotic devices to form and cultivate caring behaviors, or sufficiently develop interactive nurse-client communication necessary in the context of nursing. This article examines the disconnects created by use of simulation technology in nursing education, raising the question: "Can learning of caring-as-being, be facilitated in simulation classrooms?" We propose that unless time is spent with human beings in the earliest stages of nursing education, transpersonal caring relationships do not have space to develop. Learning, crafting, and maturation of caring behaviors threatens to become a serendipitous event or is no longer perceived as an essential characteristic of nursing. Technology does not negate caring-the isolation it fosters makes transpersonal caring all the more important. We are called to create a new paradigm for nursing education that merges Nightingale's vision with technology's promise. © 2012 Wiley Periodicals, Inc.

  13. Coordination in arm movements during crawl stroke in elite swimmers with a loco-motor disability.

    Science.gov (United States)

    Satkunskiene, Danguole; Schega, Lutz; Kunze, Katrin; Birzinyte, Kristina; Daly, Daniel

    2005-02-01

    The purpose of this study was to investigate selected kinematics parameters of the arm stroke in crawl swimmers with disabilities and to examine the potential use of an index of arm coordination (IdC) to evaluate the stroking technique of swimmers with diverse functional abilities. The degree of overlap in the propulsive phases (superposition model) and lag time between the propulsive phases (catch-up model) was examined in 18 well-trained swimmers with loco-motor disabilities, 9 females and 9 males, from functional classes S3-S10 with S10 being most functional. Based on the results, correct coordination appears to be fundamental to swimming crawl stroke in both able-bodied swimmers as well as swimmers with a disability. Some swimmers with disabilities examined here exhibited extreme values at both ends of the index scale. This might be essential to maintaining balance while swimming when not all limb activity contributes to the forward movement.

  14. Loco-regional administration of nanomedicines for the treatment of lung cancer.

    Science.gov (United States)

    Garrastazu Pereira, Gabriela; Lawson, Amanda Jane; Buttini, Francesca; Sonvico, Fabio

    2016-10-01

    Lung cancer poses one of the most significant challenges to modern medicine, killing thousands every year. Current therapy involves surgical resection supplemented with chemotherapy and radiotherapy due to high rates of relapse. Shortcomings of currently available chemotherapy protocols include unacceptably high levels of systemic toxicity and low accumulation of drug at the tumor site. Loco-regional delivery of nanocarriers loaded with anticancer agents has the potential to significantly increase efficacy, while minimizing systemic toxicity to anticancer agents. Local drug administration at the tumor site using nanoparticulate drug delivery systems can reduce systemic toxicities observed with intravenously administered anticancer drugs. In addition, this approach presents an opportunity for sustained delivery of anticancer drug over an extended period of time. Herein, the progress in the development of locally administered nanomedicines for the treatment of lung cancer is reviewed. Administration by inhalation, intratumoral injection and means of direct in situ application are discussed, the benefits and drawbacks of each modality are explored.

  15. The clinical impact of hypoxia-regulated gene expression in loco-regional gastroesophageal cancer

    DEFF Research Database (Denmark)

    Winther, M.; Alsner, J.; Tramm, T.

    2015-01-01

    squamous cell carcinomas (ESCC) compared with adenocarcinomas of the esophago-gastric junction and the stomach (AC), and was a potential prognostic marker in patients with ESCC. The purpose of the present study was to confirm these results. Materials and Methods: The study population consisted of 152......Purpose/Objective: In a former study (1), the hypoxia gene expression classifier, developed in head and neck squamous cell carcinomas, was applied in 89 patients with loco-regional gastroesophageal cancer (GC). Analysis of the 15 genes was indicative of hypoxia being more profound in esophagus...... were available in 135 patients; ESCC: 89 patients (66%), AC: 43 patients (32%) and other carcinomas: 3 patients (2%). Comparing the cohorts of the original and present study, patient characteristics were similar except for a significantly lower T- and N-stage in the present cohort. Tumor specimens were...

  16. The in loco parentis role of the teacher: A relationship perspective

    Directory of Open Access Journals (Sweden)

    I. J. Oosthuizen

    1992-03-01

    Full Text Available The parent (as the primary educator as well as the teacher (as the secondary' educator functions from independent societal units in their respective roles o f educating the educand The teacher as an in loco parents person has the right on the one hand to maintain order by means of school rules and the punishment o f transgressors and on the other hand has a duty to care for the safety o f the educands. The parent and the teacher share a common goal: the maturing and the development o f the educand. Whilst the nature o f this parent-teacher co-operation is defined as a partnership, it is - taking the technical essentials o f a partnership into account - more o f a voluntary association. This generates the question whether the whole system o f parEnt-teacher co-operation should not be reorganised on the basis o f a true partnership.

  17. Using Multicore Technologies to Speed Up Complex Simulations of Population Evolution

    Directory of Open Access Journals (Sweden)

    Mauricio Guevara-Souza

    2013-01-01

    Full Text Available We explore with the use of multicore processing technologies for conducting simulations on population replacement of disease vectors. In our model, a native population of simulated vectors is inoculated with a small exogenous population of vectors that have been infected with the Wolbachia bacteria, which confers immunity to the disease. We conducted a series of computational simulations to study the conditions required by the invading population to take over the native population. Given the computational burden of this study, we decided to take advantage of modern multicore processor technologies for reducing the time required for the simulations. Overall, the results seem promising both in terms of the application and the use of multicore technologies.

  18. Postoperative adjuvant radiotherapy improves loco-regional recurrence of head and neck mucosal melanoma.

    Science.gov (United States)

    Wushou, Alimujiang; Hou, Jing; Zhao, Ya-Jun; Miao, Xin-chao

    2015-05-01

    Primary head and neck mucosal melanoma (HNMM) is a rare tumor with a poor prognosis. Controversy remains as to whether postoperative adjuvant radiotherapy (PORT) achieves a significant benefit in HNMM treatment. Because of the lack of available conclusive prospective data, we performed a systematic review and meta-analysis of all relevant available studies to clarify the benefits of PORT. A comprehensive literature search of PubMed and Google Scholar electronic databases was conducted to collect relevant studies until April 30, 2014. Studies published in the English language comparing surgery alone and surgery plus PORT for HNMM were included, with more than 15 study populations. All statistical analyses were performed using STATA version 12.0. A total of 423 patients were available from eight studies and the median sample size was 53 cases. The median follow-up time was 38.2 months (range 18.3-65.2 months). There was a positive association between PORT and loco-regional recurrence of HNMM (odds ratio [OR] = 0.36, 95% confidence interval [CI] = 0.22-0.60, P = 0.000). No associations were found between the PORT and 3-year and 5-year overall survival (OS) (OR = 1.41, 95% CI = 0.94-2.09, P = 0.093 and OR = 1.06, 95% CI = 0.70-1.61, P = 0.161, respectively). PORT had no impact on 3-year and 5-year OS (hazard ratio [HR] = 1.14, 95% CI = 0.80-1.61, P = 0.472 and HR = 1.34, 95% CI = 0.97-1.85, P = 0.227, respectively). PORT improved loco-regional recurrence of HNMM independent of OS.

  19. Radiofrequency ablation to treat loco-regional recurrence of well-differentiated thyroid carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Jung, So Lyung; Kim, Bum Soo; Ahn, Kook Jin [Dept. of Radiology, eoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of); and others

    2014-12-15

    To evaluate the efficacy of radiofrequency ablation (RFA) in the treatment of loco-regional, recurrent, and well-differentiated thyroid carcinoma. Thirty-five recurrent well-differentiated thyroid carcinomas (RTC) in 32 patients were treated with RFA, between March 2008 and October 2011. RTCs were detected by regular follow-up ultrasound and confirmed by biopsy. All patients had fewer than 3 RTCs in the neck and were at high surgical risk or refused to undergo repeated surgery. Average number of RFA sessions were 1.3 (range 1-3). Post-RFA biopsy and ultrasound were performed. The mean follow-up period was 30 months. Pre- and post-RFA serum thyroglobulin values were evaluated. Thirty-one patients with 33 RTCs were treated with RFA only, whereas 1 patient with 2 RTCs was treated with RFA followed by surgery. At the last follow-up ultrasound, 31 (94%) of the 33 RTCs treated with RFA alone completely disappeared and the remaining 2 (6%) RTCs showed decreased volume. The largest diameter and volume of the 33 RTCs were markedly decreased by 93.2% (from 8.1 +/- 3.4 mm to 0.6 +/- 1.8 mm, p < 0.001) and 96.4% (from 173.9 +/- 198.7 mm{sup 3} to 6.2 +/- 27.9 mm{sup 3}, p < 0.001), respectively. Twenty of the 21 RTCs evaluated with post-RFA biopsies (95%) were negative for malignancy. One (5%) showed remaining tumor that was removed surgically. The serum thyroglobulin was decreased in 19 of 26 patients (73%). Voice change developed immediately after RFA in 6 patients (19%) and was spontaneously recovered in 5 patients (83%). Radiofrequency ablation can be effective in treating loco-regional, recurrent, and well-differentiated thyroid carcinoma in patients at high surgical risk.

  20. Computer simulation of tritium systems for fusion technology

    Energy Technology Data Exchange (ETDEWEB)

    Gabowitsch, E.; Spannagel, G. (Kernforschungszentrum Karlsruhe GmbH Institut fur Datenverarbeitung in der Technik Postfach 3640, D-7500 Karlsruhe 1 (DE))

    1989-09-01

    The KATRIM computer code is presented. It calculates key values of tritium systems, especially those related to complete fuel cycles. First, a deterministic model is discussed. Then, a stochastic model is presented based on dynamic systems with different dynamic states, each with its own system of equations. Such an approach allows the modeling of reactors with different degrees of availability and/or different operational strategies. Results of simulations for different availabilities, variable frequencies of interruptions in reactor operation, and changing tritium burnup in the plasma are presented.

  1. Proceedings of the workshop on molten salts technology and computer simulation

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, Hirokazu; Minato, Kazuo (eds.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-12-01

    Applications of molten salts technology to separation and synthesis of materials have been studied eagerly, which would develop new fields of materials science. Research Group for Actinides Science, Department of Materials Science, Japan Atomic Energy Research Institute (JAERI), together with Reprocessing and Recycle Technology Division, Atomic Energy Society of Japan, organized the Workshop on Molten Salts Technology and Computer Simulation at Tokai Research Establishment, JAERI on July 18, 2001. In the workshop eleven lectures were made and lively discussions were there on the fundamentals and applications of the molten salts technology that covered the structure and basic properties of molten salts, the pyrochemical reprocessing technology and the relevant computer simulation. The 10 of the presented papers are indexed individually. (J.P.N.)

  2. Simulation models and designs for advanced Fischer-Tropsch technology

    Energy Technology Data Exchange (ETDEWEB)

    Choi, G.N.; Kramer, S.J.; Tam, S.S. [Bechtel Corp., San Francisco, CA (United States)

    1995-12-31

    Process designs and economics were developed for three grass-roots indirect Fischer-Tropsch coal liquefaction facilities. A baseline and an alternate upgrading design were developed for a mine-mouth plant located in southern Illinois using Illinois No. 6 coal, and one for a mine-mouth plane located in Wyoming using Power River Basin coal. The alternate design used close-coupled ZSM-5 reactors to upgrade the vapor stream leaving the Fischer-Tropsch reactor. ASPEN process simulation models were developed for all three designs. These results have been reported previously. In this study, the ASPEN process simulation model was enhanced to improve the vapor/liquid equilibrium calculations for the products leaving the slurry bed Fischer-Tropsch reactors. This significantly improved the predictions for the alternate ZSM-5 upgrading design. Another model was developed for the Wyoming coal case using ZSM-5 upgrading of the Fischer-Tropsch reactor vapors. To date, this is the best indirect coal liquefaction case. Sensitivity studies showed that additional cost reductions are possible.

  3. Research and simulation of anti - rollover technology of harvester

    Science.gov (United States)

    Li, Shizhuang; Cao, Shukun

    2017-09-01

    The structural characteristics of our country’s corn harvester are narrow-track, high centroid and existence of eccentric distance, so rollover accident is easily to occur when going up and down the hills mountainous and hilly regions for complex terrain. In the previous paper, we introduced the Hydro-Pneumatic Suspension to prevent the roller of the harvester, and took ADAMS simulation on the left and right roller, and obtained that the use of Hydro-Pneumatic Suspension can improve the side angle of the harvester for 5°. At the same time, we continue to use the Hydro-Pneumatic Suspension as the key part of the anti-roller system of the harvester. In the uphill and downhill case of the harvester, we respectively simulated the anti-roller performance on the traditional harvester and the harvester installing the Hydro-Pneumatic Suspension. Finally, we got that the anti-roller angle of the harvester installed Hydro-Pneumatic Suspension is obviously higher than the traditional harvester, which indicates that the anti-rollover performance of the harvester installed Hydro-Pneumatic Suspension is better than the traditional harvester. The data obtained from this experiment will provide technical support for the following structure optimization of the harvester.

  4. Advanced visualization technology for terascale particle accelerator simulations

    Energy Technology Data Exchange (ETDEWEB)

    Ma, K-L; Schussman, G.; Wilson, B.; Ko, K.; Qiang, J.; Ryne, R.

    2002-11-16

    This paper presents two new hardware-assisted rendering techniques developed for interactive visualization of the terascale data generated from numerical modeling of next generation accelerator designs. The first technique, based on a hybrid rendering approach, makes possible interactive exploration of large-scale particle data from particle beam dynamics modeling. The second technique, based on a compact texture-enhanced representation, exploits the advanced features of commodity graphics cards to achieve perceptually effective visualization of the very dense and complex electromagnetic fields produced from the modeling of reflection and transmission properties of open structures in an accelerator design. Because of the collaborative nature of the overall accelerator modeling project, the visualization technology developed is for both desktop and remote visualization settings. We have tested the techniques using both time varying particle data sets containing up to one billion particle s per time step and electromagnetic field data sets with millions of mesh elements.

  5. Comparing Natural Gas Leakage Detection Technologies Using an Open-Source "Virtual Gas Field" Simulator.

    Science.gov (United States)

    Kemp, Chandler E; Ravikumar, Arvind P; Brandt, Adam R

    2016-04-19

    We present a tool for modeling the performance of methane leak detection and repair programs that can be used to evaluate the effectiveness of detection technologies and proposed mitigation policies. The tool uses a two-state Markov model to simulate the evolution of methane leakage from an artificial natural gas field. Leaks are created stochastically, drawing from the current understanding of the frequency and size distributions at production facilities. Various leak detection and repair programs can be simulated to determine the rate at which each would identify and repair leaks. Integrating the methane leakage over time enables a meaningful comparison between technologies, using both economic and environmental metrics. We simulate four existing or proposed detection technologies: flame ionization detection, manual infrared camera, automated infrared drone, and distributed detectors. Comparing these four technologies, we found that over 80% of simulated leakage could be mitigated with a positive net present value, although the maximum benefit is realized by selectively targeting larger leaks. Our results show that low-cost leak detection programs can rely on high-cost technology, as long as it is applied in a way that allows for rapid detection of large leaks. Any strategy to reduce leakage should require a careful consideration of the differences between low-cost technologies and low-cost programs.

  6. Tumor markers for early diagnosis for brain metastasis of hepatocellular carcinoma: A case series and literature review for effective loco-regional treatment.

    Science.gov (United States)

    Kamimura, Kenya; Kobayashi, Yuji; Takahashi, Yoshifumi; Abe, Hiroyuki; Kumaki, Daisuke; Yokoo, Takeshi; Kamimura, Hiroteru; Sakai, Norihiro; Sakamaki, Akira; Abe, Satoshi; Takamura, Masaaki; Kawai, Hirokazu; Yamagiwa, Satoshi; Terai, Shuji

    2017-02-01

    Intrahepatic lesions of hepatocellular carcinoma (HCC) have been controlled by significant advances in treatment using loco-regional therapies, including, surgery, ablative therapy, catheter-based chemotherapy, and embolization. Consequently, the number of patients with extrahepatic metastatic lesions has increased. Their prognosis remains poor with approximately loco-regional treatment, including surgical resection and radiation therapy should be performed for better prognosis by preventing re-bleeding from the tumors.

  7. Simulation Technology of Environmental Impacts by Zero-energy Residential Buildings Based on Emergy Analysis Method

    Institute of Scientific and Technical Information of China (English)

    Hong Zhou; XiaoLong Xue; WangShu Yang

    2014-01-01

    This paper presents a simulation technology of environmental impact for the building. By emergy analysis method, emergy costs of building( or construction engineering) can be calculated in the life cycle. It includes the engineering cost, environmental cost and social cost of building. Through integrating GIS technology with multi-agent technology, life cycle substance and energy metabolism of building ( construction engineering) can be simulated and their environmental influence can be dynamically displayed. Based on the case study of entries works ‘Sunny Inside’ by Xiamen University in 2013 China International Solar Decathlon Competition, we discovered the changing pattern of surrounding environmental impact from waste streams of the zero-energy building and ordinary construction. The simulation results verified and showed the Odum principles of maximum power. This paper provides a new research perspective and integration approach for the environmental impact assessment in building and construction engineering. The result will help decision-making in design and construction engineering scheme.

  8. Technology-enhanced simulation in emergency medicine: a systematic review and meta-analysis.

    Science.gov (United States)

    Ilgen, Jonathan S; Sherbino, Jonathan; Cook, David A

    2013-02-01

    Technology-enhanced simulation is used frequently in emergency medicine (EM) training programs. Evidence for its effectiveness, however, remains unclear. The objective of this study was to evaluate the effectiveness of technology-enhanced simulation for training in EM and identify instructional design features associated with improved outcomes by conducting a systematic review. The authors systematically searched MEDLINE, EMBASE, CINAHL, ERIC, PsychINFO, Scopus, key journals, and previous review bibliographies through May 2011. Original research articles in any language were selected if they compared simulation to no intervention or another educational activity for the purposes of training EM health professionals (including student and practicing physicians, midlevel providers, nurses, and prehospital providers). Reviewers evaluated study quality and abstracted information on learners, instructional design (curricular integration, feedback, repetitive practice, mastery learning), and outcomes. From a collection of 10,903 articles, 85 eligible studies enrolling 6,099 EM learners were identified. Of these, 56 studies compared simulation to no intervention, 12 compared simulation with another form of instruction, and 19 compared two forms of simulation. Effect sizes were pooled using a random-effects model. Heterogeneity among these studies was large (I(2) ≥ 50%). Among studies comparing simulation to no intervention, pooled effect sizes were large (range = 1.13 to 1.48) for knowledge, time, and skills and small to moderate for behaviors with patients (0.62) and patient effects (0.43; all p 0.1). Qualitative comparisons of different simulation curricula are limited, although feedback, mastery learning, and higher fidelity were associated with improved learning outcomes. Technology-enhanced simulation for EM learners is associated with moderate or large favorable effects in comparison with no intervention and generally small and nonsignificant benefits in comparison

  9. Advanced simulation technology for etching process design for CMOS device applications

    Science.gov (United States)

    Kuboi, Nobuyuki; Fukasawa, Masanaga; Tatsumi, Tetsuya

    2016-07-01

    Plasma etching is a critical process for the realization of high performance in the next generation of CMOS devices. To predict and control fluctuations in the etching properties accurately during mass production, it is essential that etching process simulation technology considers fluctuations in the plasma chamber wall conditions, the effects of by-products on the critical dimensions, the Si recess dependence on the wafer open area ratio and local pattern structure, and the time-dependent plasma-induced damage distribution associated with the three-dimensional feature scale profile at the 100 nm level. This consideration can overcome the issues with conventional simulations performed under the assumed ideal conditions, which are not accurate enough for practical process design. In this article, these advanced process simulation technologies are reviewed, and, from the results of suitable process simulations, a new etching system that automatically controls the etching properties is proposed to enable stable CMOS device fabrication with high yields.

  10. The Application of the Technology of 3D Satellite Cloud Imaging in Virtual Reality Simulation

    Directory of Open Access Journals (Sweden)

    Xiao-fang Xie

    2007-05-01

    Full Text Available Using satellite cloud images to simulate clouds is one of the new visual simulation technologies in Virtual Reality (VR. Taking the original data of satellite cloud images as the source, this paper depicts specifically the technology of 3D satellite cloud imaging through the transforming of coordinates and projection, creating a DEM (Digital Elevation Model of cloud imaging and 3D simulation. A Mercator projection was introduced to create a cloud image DEM, while solutions for geodetic problems were introduced to calculate distances, and the outer-trajectory science of rockets was introduced to obtain the elevation of clouds. For demonstration, we report on a computer program to simulate the 3D satellite cloud images.

  11. Issues Affecting the Loco-regional and Systemic Management of Patients with Invasive Lobular Carcinoma of the Breast.

    Science.gov (United States)

    Jacobs, Carmel; Clemons, Mark; Addison, Christina; Robertson, Susan; Arnaout, Angel

    2016-01-01

    Invasive lobular carcinoma (ILC) of the breast is the second most common type of invasive breast carcinoma accounting for 8-14% of all breast cancers. Traditional management of ILC has followed similar paradigms as that for invasive ductal carcinoma (IDC). However, ILC represents a pathologically, clinically and biologically unique variant of breast cancer with particular management challenges. These challenges are seen in both the loco-regional management of ILC; where ILC tumors tend to avoid detection and hence present as more clinically advanced and surgically challenging carcinomas, and the systemic management with a unique response pattern to standard systemic therapies. Because of these challenges, the outcome for patients with ILC has likely lagged behind the continued improvements seen in outcome for patients with IDC. Here, we discuss some of the unique challenges ILC presents and discuss possible management strategies to best overcome the difficulties in the loco-regional and systemic management of patients with ILC.

  12. Numerical simulation of the stress – strain state of technological tools for fine drawing

    OpenAIRE

    Порубов, А. В.; Мельникова, Т. Е.

    2014-01-01

    An urgent task is to ensure the long life of the technological tool, namely the expensive diamond dies, which can significantly improve the efficiency of the production of wire. Strength Evaluation of technological tools, numerical simulation of the stress – strain state of the diamond drawing tool in the finite – element package ANSYS. Calculation of strain and stress state of the diamond drawing tool for drawing copper and nickel – plated wire with the operating pressure and the pressing fo...

  13. Virtual reality simulation: using three-dimensional technology to teach nursing students.

    Science.gov (United States)

    Jenson, Carole E; Forsyth, Diane McNally

    2012-06-01

    The use of computerized technology is rapidly growing in the classroom and in healthcare. An emerging computer technology strategy for nursing education is the use of virtual reality simulation. This computer-based three-dimensional educational tool simulates real-life patient experiences in a risk-free environment, allows for repeated practice sessions, requires clinical decision making, exposes students to diverse patient conditions, provides immediate feedback, and is portable. The purpose of this article was to review the importance of virtual reality simulation as a computerized teaching strategy. In addition, a project to explore readiness of nursing faculty at one major Midwestern university for the use of virtual reality simulation as a computerized teaching strategy is described where faculty thought virtual reality simulation would increase students' knowledge of an intravenous line insertion procedure. Faculty who practiced intravenous catheter insertion via virtual reality simulation expressed a wide range of learning experiences from using virtual reality simulation that is congruent with the literature regarding the barriers to student learning. Innovative teaching strategies, such as virtual reality simulation, address barriers of increasing patient acuity, high student-to-faculty ratio, patient safety concerns from faculty, and student anxiety and can offer rapid feedback to students.

  14. Technological and Economic Risk Analysis of laying hen breeding applying simulation

    OpenAIRE

    Kovacs, Sandor; Ertsey, Imre; Balogh, Peter

    2007-01-01

    In order to analyse risks and to choose from different decision-making strategies simulation models are often applied in several areas of animal breeding. We developed an improved Monte Carlo model for analysing laying hen breeding combined with Bayes statistics. On the basis of data from a company breeding broiler parents, our paper examines the technological and economic risks of breeding a laying-hen stock with a simulation program developed by our team. During modelling we take individual...

  15. Dynamic localization of C. elegans TPR-GoLoco proteins mediates mitotic spindle orientation by extrinsic signaling.

    Science.gov (United States)

    Werts, Adam D; Roh-Johnson, Minna; Goldstein, Bob

    2011-10-01

    Cell divisions are sometimes oriented by extrinsic signals, by mechanisms that are poorly understood. Proteins containing TPR and GoLoco-domains (C. elegans GPR-1/2, Drosophila Pins, vertebrate LGN and AGS3) are candidates for mediating mitotic spindle orientation by extrinsic signals, but the mechanisms by which TPR-GoLoco proteins may localize in response to extrinsic cues are not well defined. The C. elegans TPR-GoLoco protein pair GPR-1/2 is enriched at a site of contact between two cells - the endomesodermal precursor EMS and the germline precursor P(2) - and both cells align their divisions toward this shared cell-cell contact. To determine whether GPR-1/2 is enriched at this site within both cells, we generated mosaic embryos with GPR-1/2 bearing a different fluorescent tag in different cells. We were surprised to find that GPR-1/2 distribution is symmetric in EMS, where GPR-1/2 had been proposed to function as an asymmetric cue for spindle orientation. Instead, GPR-1/2 is asymmetrically distributed only in P(2). We demonstrate a role for normal GPR-1/2 localization in P(2) division orientation. We show that MES-1/Src signaling plays an instructive role in P(2) for asymmetric GPR-1/2 localization and normal spindle orientation. We ruled out a model in which signaling localizes GPR-1/2 by locally inhibiting LET-99, a GPR-1/2 antagonist. Instead, asymmetric GPR-1/2 distribution is established by destabilization at one cell contact, diffusion, and trapping at another cell contact. Once the mitotic spindle of P(2) is oriented normally, microtubule-dependent removal of GPR-1/2 prevented excess accumulation, in an apparent negative-feedback loop. These results highlight the role of dynamic TPR-GoLoco protein localization as a key mediator of mitotic spindle alignment in response to instructive, external cues.

  16. Digital scene simulation /SUP sm/: The synergy of computer technology and human creativity

    Energy Technology Data Exchange (ETDEWEB)

    Demos, G.; Brown, M.D.; Weinberg, R.A.

    1984-01-01

    Digital Scene Simulation is Digital Productions' philosophy for creating visual excellence in computer-generated imagery and simulation. The approach it advocates requires the use of powerful hardware, sophisticated software, and top creative talent. With a CRAY supercomputer at the heart of its computer network and its own proprietary image rendering and simulation software, Digital Productions is revolutionizing state-of-the-art computer graphics. At the forefront of computer graphics technology, Digital Productions is redefining traditional methods of visual communications and creating new forms of self-expression, instruction, and entertainment.

  17. Editorial: Advances in Health Education Applying E-Learning, Simulations and Distance Technologies

    Directory of Open Access Journals (Sweden)

    Andre W. Kushniruk

    2011-03-01

    Full Text Available This special issue of the KM&EL international journal is dedicated to coverage of novel advances in health professional education applying e-Learning, simulations and distance education technologies. Modern healthcare is beginning to be transformed through the emergence of new information technologies and rapid advances in health informatics. Advances such as electronic health record systems (EHRs, clinical decision support systems and other advanced information systems such as public health surveillance systems are rapidly being deployed worldwide. The education of health professionals such as medical, nursing and allied health professionals will require an improved understanding of these technologies and how they will transform their healthcare practice. However, currently there is a lack of integration of knowledge and skills related to such technology in health professional education. In this issue of the journal we present articles that describe a set of novel approaches to integrating essential health information technology into the education of health professionals, as well as the use of advanced information technologies and e-Learning approaches for improving health professional education. The approaches range from use of simulations to development of novel Web-based platforms for allowing students to interact with the technologies and healthcare practices that are rapidly changing healthcare.

  18. Modelling and Simulation of ERTMS for Current and Future Mobile Technologies

    Directory of Open Access Journals (Sweden)

    Christian Pinedo

    2015-01-01

    Full Text Available Nowadays, train control in-lab simulation tools play a crucial role in reducing extensive and expensive on-site railway testing activities. In this paper, we present our contribution in this arena by detailing the internals of our European Railway Train Management System in-lab demonstrator. This demonstrator is built over a general-purpose simulation framework, Riverbed Modeler, previously Opnet Modeler. Our framework models both ERTMS subsystems, the Automatic Train Protection application layer based on movement authority message exchange and the telecommunication subsystem based on GSM-R communication technology. We provide detailed information on our modelling strategy. We also validate our simulation framework with real trace data. To conclude, under current industry migration scenario from GSM-R legacy obsolescence to IP-based heterogeneous technologies, our simulation framework represents a singular tool to railway operators. As an example, we present the assessment of related performance indicators for a specific railway network using a candidate replacement technology, LTE, versus current legacy technology. To the best of our knowledge, there is no similar initiative able to measure the impact of the telecommunication subsystem in the railway network availability.

  19. The Value Simulation-Based Learning Added to Machining Technology in Singapore

    Science.gov (United States)

    Fang, Linda; Tan, Hock Soon; Thwin, Mya Mya; Tan, Kim Cheng; Koh, Caroline

    2011-01-01

    This study seeks to understand the value simulation-based learning (SBL) added to the learning of Machining Technology in a 15-week core subject course offered to university students. The research questions were: (1) How did SBL enhance classroom learning? (2) How did SBL help participants in their test? (3) How did SBL prepare participants for…

  20. Standard Lunar Regolith Simulants for Space Resource Utilization Technologies Development: Effects of Materials Choices

    Science.gov (United States)

    Sibille, Laurent; Carpenter, Paul K.

    2006-01-01

    As NASA turns its exploration ambitions towards the Moon once again, the research and development of new technologies for lunar operations face the challenge of meeting the milestones of a fastpace schedule, reminiscent of the 1960's Apollo program. While the lunar samples returned by the Apollo and Luna missions have revealed much about the Moon, these priceless materials exist in too scarce quantities to be used for technology development and testing. The need for mineral materials chosen to simulate the characteristics of lunar regoliths is a pressing issue that is being addressed today through the collaboration of scientists, engineers and NASA program managers. The issue of reproducing the properties of lunar regolith for research and technology development purposes was addressed by the recently held 2005 Workshop on Lunar Regolith Simulant Materials at Marshall Space Flight Center. The recommendation of the workshop of establishing standard simulant materials to be used in lunar technology development and testing will be discussed here with an emphasis on space resource utilization. The variety of techniques and the complexity of functional interfaces make these simulant choices critical in space resource utilization.

  1. Learning Outcomes from Business Simulation Exercises: Challenges for the Implementation of Learning Technologies

    Science.gov (United States)

    Clarke, Elizabeth

    2009-01-01

    Purpose: High order leadership, problem solving skills, and the capacity for innovation in new markets, and technologically complex and multidimensional contexts, are the new set of skills that are most valued by companies and employers alike. Business simulation exercises are one way of enhancing these skills. This article aims to examine the…

  2. Development of a simulation environment to test space missions COTS technologies

    Science.gov (United States)

    Saraf, S.; Knoll, A.; Melanson, P.; Tafazoli, M.

    2002-07-01

    The Canadian Space Agency's (CSA) Software and Ground Segment Section (SGS) has the mandate to develop innovative emerging software and on-board satellite and ground segment computer technologies. To that end, there is an ongoing development of a simulation environment to test COTS (Commercial-Of-The-Shelf) technologies. There are severe cost constraints in all aspects of many space missions due to the limited return on investment and scarce commercialization opportunities that come with many science missions. There is an opportunity to explore the innovative implementation of COTS technologies to reduce the mission cost and maximize performance available from COTS components. However, using COTS technologies in the space environment has ist constraints and therefore designing a spacecraft mission has to involve some new techniques that allow implementation of these components and minimize the risk of failure. The goal of our project is to develop a simulation environment, itself using COTS components, and then to allow the seamless integration of various components to test spacecraft mission concepts. For example, one of the aspects of using COTS processors in space is to protect them from the radiation environment. The current state of the simulation tests an innovative software EDAC (Error Detection and Correction) package and a redundant processor configuration to investigate protection against the effects of radiation and other failures on a generic mission. It also includes the capability to test formation-flying concepts that have the potential to revolutionize cost reduction efforts for space missions and to enable new space applications. This paper describes the simulation environment in detail and illustrates some of the technologies being tested for possible future space missions. The paper concludes with a look at the future development of the simulation environment and possible benefits of its use as well as the lessons learned to date.

  3. Loco-regional therapies for patients with hepatocellular carcinoma awaiting liver transplantation: Selecting an optimal therapy.

    Science.gov (United States)

    Byrne, Thomas J; Rakela, Jorge

    2016-06-24

    Hepatocellular carcinoma (HCC) is a common, increasingly prevalent malignancy. For all but the smallest lesions, surgical removal of cancer via resection or liver transplantation (LT) is considered the most feasible pathway to cure. Resection - even with favorable survival - is associated with a fairly high rate of recurrence, perhaps since most HCCs occur in the setting of cirrhosis. LT offers the advantage of removing not only the cancer but the diseased liver from which the cancer has arisen, and LT outperforms resection for survival with selected patients. Since time waiting for LT is time during which HCC can progress, loco-regional therapy (LRT) is widely employed by transplant centers. The purpose of LRT is either to bridge patients to LT by preventing progression and waitlist dropout, or to downstage patients who slightly exceed standard eligibility criteria initially but can fall within it after treatment. Transarterial chemoembolization and radiofrequency ablation have been the most widely utilized LRTs to date, with favorable efficacy and safety as a bridge to LT (and for the former, as a downstaging modality). The list of potentially effective LRTs has expanded in recent years, and includes transarterial chemoembolization with drug-eluting beads, radioembolization and novel forms of extracorporal therapy. Herein we appraise the various LRT modalities for HCC, and their potential roles in specific clinical scenarios in patients awaiting LT.

  4. PEDAGOGICAL TOURISM AS A TEACHING STRATEGY: EXPLORING THE IN LOCO IN THE TOURISM PROFESSIONAL TEACHING

    Directory of Open Access Journals (Sweden)

    Thais Gaia Schüler

    2016-07-01

    Full Text Available The article focuses on the discussion about the teaching experience of exploring the pedagogical tourism in the technical and professional teaching of Tourism accomplished through the case study of the Technical Course in Tourism held in the State Technical School São João Batista and decentralized classes. It was all developed based on the interpretative-idealistic paradigm, using the inductive method for discussion, having the data based on interviews, questionnaires and on the author´s praxis observation. When there was a change from the school curriculum divided in school subjects to a new curricular structure per skills, the teachers discussions pointed at the need of taking the students to field, showing the professional practice in loco and inserting a methodological strategy linked to the concept of Pedagogical Tourism. Since then, it was adopted the “technical field trips” not as an additional activity, but as part of the course teaching methodology, in order to create situations which made the student closer to the chosen professional reality. Three years after this methodology implementation, the goal is a pedagogical evaluation, pointing at advantages, disadvantages and the perceptions of students, teachers and school managers involved in the process.

  5. Cervantes en escena: El loco de la guardilla, de Narciso Serra

    Directory of Open Access Journals (Sweden)

    Menéndez Onrubia, Carmen

    2004-04-01

    Full Text Available El éxito obtenido por las tropas españolas en la Guerra de Marruecos (1859-1860 y la anexión a la corona de la isla de Santo Domingo (marzo de 1861, produjo en España un ambiente de exaltación patriótica inusitado. Sentido Cervantes por aquel entonces como el mayor representante de la lengua y de la literatura española, y crisol de la esencial nacional, recibió en 1861 sentidos homenajes populares en los escenarios madrileños. Así, se sucedieron las funciones que en reconocimiento a la peripecia vital y literaria del escritor alcalaíno se le dedicaron en el teatro del Príncipe (23-IV-1861, en el de Novedades (entre el 9 y el 23 de octubre y en la Zarzuela con el estreno del «paso» de Narciso Serra El loco de la guardilla.…

  6. Modificações texturais de tomates heterozigotos no loco alcobaça

    Directory of Open Access Journals (Sweden)

    VILAS BOAS EDUARDO VALÉRIO DE BARROS

    2000-01-01

    Full Text Available Foram avaliadas as modificações ocorridas durante o amadurecimento de três pares de híbridos de tomates do grupo multilocular, quase isogênicos, à exceção do loco alcobaça. O experimento foi conduzido na Universidade Federal de Lavras, em delineamento em blocos casualizados. Os pares de híbridos (Stevens x Flora Dade e Stevens x TOM-559; Piedmont x Flora Dade e Piedmont x TOM-559; NC-8276 x Flora Dade e NC-8276 x TOM-559 foram avaliados em quatro estádios de amadurecimento (breaker, rosa, vermelho-claro e vermelho, em quatro repetições. Os híbridos cujo genitor comum foi Flora Dade corresponderam ao genótipo normal (+/+, enquanto os híbridos heterozigotos alcobaça (+/alc foram provenientes do genitor comum TOM-559. A textura não foi afetada pelo alelo alcobaça nos estádios predeterminados de amadurecimento. Já a porcentagem de solubilização das substâncias pécticas, bem como a atividade das enzimas pectinametilesterase e poligalacturonase, foram influenciadas pelo alelo alcobaça, que determinou a sua contenção. O amadurecimento dos tomates (+/+ e (+/alc foi marcado por intenso amaciamento, acompanhado por incremento na atividade da poligalacturonase e solubilização das substâncias pécticas.

  7. Simulation

    DEFF Research Database (Denmark)

    Gould, Derek A; Chalmers, Nicholas; Johnson, Sheena J

    2012-01-01

    Recognition of the many limitations of traditional apprenticeship training is driving new approaches to learning medical procedural skills. Among simulation technologies and methods available today, computer-based systems are topical and bring the benefits of automated, repeatable, and reliable p...... performance assessments. Human factors research is central to simulator model development that is relevant to real-world imaging-guided interventional tasks and to the credentialing programs in which it would be used.......Recognition of the many limitations of traditional apprenticeship training is driving new approaches to learning medical procedural skills. Among simulation technologies and methods available today, computer-based systems are topical and bring the benefits of automated, repeatable, and reliable...

  8. MAIN DIRECTIONS OF THE DEVELOPMENT OF PROGRAM-IMITATING SIMULATORS TECHNOLOGY IN THE SPHERE OF MILITARY EDUCATION

    Directory of Open Access Journals (Sweden)

    Oleh Yu. Shyshka

    2014-09-01

    Full Text Available The article considers the directions of software simulators development in the professional training of military personnel. It is outlined the theoretical approaches to understanding ICT training. The authors found out the essential features of the concepts of "software simulator", "educational technology", "technology of education", "programmed training". The article analyzes the domestic, foreign and international experience of using software simulators in the military education sphere. It presents the general trend of implementation of information and communication technologies and their impact on defined areas of development professional military software simulators.

  9. Development of Ubiquitous Simulation Service Structure Based on High Performance Computing Technologies

    Institute of Scientific and Technical Information of China (English)

    Sang-Hyun CHO; Jeong-Kil CHOI

    2008-01-01

    The simulation field became essential in designing or developing new casting products and in improving manufacturing processes within limited time, because it can help us to simulate the nature of processing, so that developers can make ideal casting designs. To take the prior occupation at commercial simulation market, so many development groups in the world are doing their every effort. They already reported successful stories in manufacturing fields by developing and providing the high performance simulation technologies for multipurpose. But they all run at powerful desk-side computers by well-trained experts mainly, so that it is hard to diffuse the scientific designing concept to newcomers in casting field. To overcome upcoming problems in scientific casting designs, we utilized information technologies and full-matured hardware backbones to spread out the effective and scientific casting design mind, and they all were integrated into Simulation Portal on the web. It professes scientific casting design on the NET including ubiquitous access way represented by "Anyone, Anytime, Anywhere" concept for casting designs.

  10. Three technological enhancements in nursing education: informatics instruction, personal response systems, and human patient simulation.

    Science.gov (United States)

    Jensen, Rebecca; Meyer, Linda; Sternberger, Carol

    2009-03-01

    With the healthcare system in a state of flux, nursing education faces many challenges. Nursing faculty must design a dynamic curriculum that deals with the explosion of information, the complexity of the healthcare system, and optimal patient outcomes while addressing the diverse expectations of learners. Inclusion of information management and interactive technology facilitates learner engagement promoting critical thinking and improving clinical judgment. This paper details the faculty's vision for an ubiquitous information technology curricula, highlighting an undergraduate informatics course, use of a personal response system, and integration of human patient simulations.

  11. Modeling and simulation of ion energy distribution functions in technological plasmas

    CERN Document Server

    Mussenbrock, Thomas

    2011-01-01

    The highly advanced treatment of surfaces as etching and deposition is mainly enabled by the extraordinary properties of technological plasmas. The primary factors that influence these processes are the flux and the energy of various species, particularly ions, that impinge the substrate surface. These features can be theoretically described using the ion energy distribution function (IEDF). The article is intended to summarize the fundamental concepts of modeling and simulation of IEDFs from simplified models to self-consistent plasma simulations. Finally, concepts for controlling the IEDF are discussed.

  12. Simulation and rubrics: technology and grading student performance in nurse anesthesia education.

    Science.gov (United States)

    Overstreet, Maria; McCarver, Lewis; Shields, John; Patterson, Jordan

    2015-06-01

    The use of simulation technology has introduced a challenge for simulation nurse educators: evaluation of student performance. The subjectivity of student performance evaluation has been in need of improvement. It is imperative to provide clear and consistent information to the learner of expectations for their performance. Educators use objectives to define for the learner what the primary focus will be in the learning activities. Creation of rubrics to replace checklists to evaluate learner performance is a team task. Improved rubrics assist instructors in providing valuable, immediate, and postactivity feedback and consistency among instructors, and improved inter-rater reliability.

  13. Exporting simulation technology to the Philippines: a comparative study of traditional versus simulation methods for teaching intravenous cannulation.

    Science.gov (United States)

    Sotto, Juan Alejandro R; Ayuste, Eduardo C; Bowyer, Mark W; Almonte, Josefina R; Dofitas, Rodney B; Lapitan, Marie C M; Pimentel, Elisabeth A; Ritter, E Matthew; Wherry, David C

    2009-01-01

    This study examines effectiveness of a donated Laerdal Virtual I.V. simulator when compared with traditional methods of teaching intravenous (IV) cannulation to third year medical students in the Philippines. Forty novice Filipino medical students viewed an instructional video on how to start intravenous lines and were then randomly divided into two groups of twenty. The "Traditional" group observed an IV insertion on an actual patient performed by an experienced practitioner, and then subsequently performed an IV on an actual patient which was videotaped. The "Simulation" group practiced the Virtual I.V. simulator until they successfully completed level three using the "doctor" setting. These students then performed an IV on an actual patient which was videotaped. The videotapes for both groups were reviewed by two pre-trained (Inter-rater reliability of > or =0.84) observers who were blinded to the group using a previously validated checklist for IV insertion. Students trained on the Virtual I.V. showed significantly greater success in successfully starting an IV on an actual patient (40% VS. 15%, p<0.05), decreased constrictive band time (p<.05), increased raw score on the check list (p<.03), and decreased overall time to start an IV (p<.05). The technology was well received but wider application in the non western world is limited by lack of in country company support and the relative expense.

  14. The Simulation of the Brush Stroke Based on Force Feedback Technology

    Directory of Open Access Journals (Sweden)

    Chao Guo

    2015-01-01

    Full Text Available A novel simulation method of the brush stroke is proposed by applying force feedback technology to the virtual painting process. The relationship between force and the brush deformation is analyzed, and the spring-mass model is applied to construct the brush model, which can realistically simulate the brush morphological changes according to the force exerted on it. According to the deformation of the brush model at a sampling point, the brush footprint between the brush and the paper is calculated in real time. Then, the brush stroke is obtained by superimposing brush footprints along sampling points, and the dynamic painting of the brush stroke is implemented. The proposed method has been successfully applied to the virtual painting system based on the force feedback technology. In this system, users can implement the painting in real time with a Phantom Desktop haptic device, which can effectively enhance reality to users.

  15. FE-Simulation of Technology of Upsetting φ73×5.51 EU Tubing

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The FE-simulation software can be used to simulate and to optimize a system with computer, even before the system is designed. After a number of FE-simulations, main equipment and technological parameters for upsetting φ73×5.51 EU tubing have been obtained.

  16. Comparison of MRI and PET-CT in detecting the loco-regional recurrence of soft tissue sarcomas during surveillance

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sun-Young [University of Ulsan College of Medicine, Asan Medical Center, Department of Radiology and Research Institute of Radiology, 88, Olympic-ro 43-gil, Songpa-gu, Seoul (Korea, Republic of); Hallym University Sacred Heart Hospital, Department of Radiology, Anyang-si, Gyeonggi-do (Korea, Republic of); Chung, Hye Won [University of Ulsan College of Medicine, Asan Medical Center, Department of Radiology and Research Institute of Radiology, 88, Olympic-ro 43-gil, Songpa-gu, Seoul (Korea, Republic of); Chae, Sun Young [University of Ulsan College of Medicine, Asan Medical Center, Department of Nuclear Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul (Korea, Republic of); Lee, Jong-Seok [University of Ulsan College of Medicine, Asan Medical Center, Department of Orthopedic Surgery, 88, Olympic-ro 43-gil, Songpa-gu, Seoul (Korea, Republic of)

    2016-10-15

    To investigate the diagnostic performance of MRI and PET-CT for the detection of loco-regional recurrences after soft tissue sarcoma (STS) excision. From Dec 2003 to Aug 2014, 394 patients with STSs, who were included in the electronic patient registry for initial or repeated surgery at our hospital, were retrospectively reviewed. We identified 152 patients who underwent regular postoperative follow-ups with both MRI and PET-CT, obtained within a 3 month period of each other. We analyzed differences in the performance of MRI and PET-CT for the diagnosis of loco-regional recurrences using McNemar's test. The receiver-operating characteristic curves and calculations of the area under the curve were used. Twenty patients were found to have a loco-regional recurrence after tumor excision. For MRI and PET-CT, the sensitivities were 90.0 and 95.0 %, and the specificities 97.7 and 95.5 %, respectively, with positive predictive values of 85.7 and 76.0 % and negative predictive values of 98.5 and 99.2 %, respectively. No significant difference was detected between the sensitivities of MRI and PET-CT (p = 0.125). The area under the receiver-operating characteristic curve for PET-CT (0.952) was not significantly greater than that for MRI (0.939; p = 0.6). MRI of the area of interest is recommended for evaluation of tumor recurrence after surgical excision of STS. PET-CT was shown to be effective for detection of STS recurrence, and comparable to MRI. However, if PET-CT or MRI findings are inconclusive, the other modality may be helpful in differentiating tumor recurrence from post-therapeutic tissue change. (orig.)

  17. Value of subtraction MRI in assessing treatment response following image-guided loco-regional therapies for hepatocellular carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Winters, S.D. [Department of Radiology and Diagnostic Imaging, Royal Alexandra Hospital, Edmonton (Canada); Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton (Canada); 1 Canadian Field Hospital, Department of National Defence, Government of Canada (Canada); Jackson, S. [Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton (Canada); Armstrong, G.A. [Department of Radiology and Diagnostic Imaging, Royal Alexandra Hospital, Edmonton (Canada); Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton (Canada); Birchall, I.W. [Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton (Canada); Lee, K.H.Y. [Department of Radiology and Diagnostic Imaging, Royal Alexandra Hospital, Edmonton (Canada); Low, G., E-mail: timgy@yahoo.com [Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton (Canada)

    2012-07-15

    Aim: To compare contrast-enhanced subtraction magnetic resonance imaging (MRI) with contrast-enhanced standard MRI in assessing treatment response following loco-regional therapies for hepatocellular carcinoma (HCC). Method and materials: Institutional review board approval was obtained and informed consent was waived for this retrospective study. All patients were analysed from our institution's liver tumour database that had loco-regional HCC therapy and the following: (1) a contrast-enhanced MRI {<=}6 weeks post-treatment, (2) an unenhanced T1-weighted high-signal treatment zone (TZ) {>=}1 cm, (3) follow-up contrast-enhanced MRI performed {>=}6 months post-treatment. Randomized standard and subtraction TZ datasets were independently assessed by three blinded radiology readers for either complete treatment necrosis or residual disease. The standard of reference (SOR) comprised a consensus read by two radiologists with knowledge of the follow-up MRI and all available clinical data. Statistical analyses were performed using receiver operating characteristics (ROC), t-test, and kappa statistic. Results: Twenty-six patients (19 male and seven female patients; mean age 60 years, standard deviation 10.9 years, range 46-88 years) had a total of 45 corresponding HCCs and TZs. For ROC, the area under the curve (AUC) was 0.93 (subtraction protocol) versus 0.90 (standard protocol; p = 0.49). For the t-test, the mean reader confidence level was 4.4, 3.6, and 4.4 (subtraction protocol) versus 3, 3, and 3.7 (standard protocol; p {<=} 0.011). The kappa statistic for reader-to-SOR agreement was 0.83, 0.63, and 0.71 (subtraction protocol) versus 0.51, 0.36, and 0.64 (standard protocol). Conclusion: Subtraction MRI significantly improves the reader confidence level in the assessment of treatment response following loco-regional therapies for HCC.

  18. Game-based Learning in Technology Management Education: A Novel Business Simulation

    Directory of Open Access Journals (Sweden)

    Markus Günther

    2011-03-01

    Full Text Available Management games allow students to obtain valuable first-hand experience that is of particular value in a field such as technology management, which usually involves substantial risk as well as significant time lags between a managerial decision and its effects. In drawing from more than fifteen years of experience with management games in higher education, we have developed a management simulation for teaching technology management, a field that is increasingly regarded an important area of study for engineering students. This paper outlines a blended-learning design for a course on technology management, describes the various didactical elements as well as their effects in class, and addresses the technical implementation of the management game as a service-oriented multi-tier application in Java.

  19. Preventing technology-induced errors in healthcare: the role of simulation.

    Science.gov (United States)

    Kushniruk, Andre W; Borycki, Elizabeth M; Anderson, James G; Anderson, Marilyn M

    2009-01-01

    We describe a novel approach to the study and prediction of technology-induced error in healthcare. The objective of our approach is to identify and reduce the potential for error so that the benefits of introducing information technology, such as Computerized Physician Order Entry (CPOE) or Electronic Health Records (EHRs), are maximized. The approach involves four phases. In Phase 1, we typically conduct small scale clinical simulations to assess whether or not the use of a new information technology can introduce error. (Human subjects are involved and user-system interactions are recorded.) In Phase 2, we analyze the results from Phase 1 to identify statistically significant relationships between usability issues and the occurrence of error (e.g., medication error). In Phase 3, we enter the results from Phase 2 into computer-based simulation models to explore the potential impact of the technology over time and across user populations. In Phase 4, we conduct naturalistic studies to examine whether or not the predictions made in Phases 2 and 3 apply to the real world. In closing, we discuss how the approach can be used to increase the safety of health information systems.

  20. Evolutionary Agent-Based Simulation of the Introduction of New Technologies in Air Traffic Management

    Science.gov (United States)

    Yliniemi, Logan; Agogino, Adrian K.; Tumer, Kagan

    2014-01-01

    Accurate simulation of the effects of integrating new technologies into a complex system is critical to the modernization of our antiquated air traffic system, where there exist many layers of interacting procedures, controls, and automation all designed to cooperate with human operators. Additions of even simple new technologies may result in unexpected emergent behavior due to complex human/ machine interactions. One approach is to create high-fidelity human models coming from the field of human factors that can simulate a rich set of behaviors. However, such models are difficult to produce, especially to show unexpected emergent behavior coming from many human operators interacting simultaneously within a complex system. Instead of engineering complex human models, we directly model the emergent behavior by evolving goal directed agents, representing human users. Using evolution we can predict how the agent representing the human user reacts given his/her goals. In this paradigm, each autonomous agent in a system pursues individual goals, and the behavior of the system emerges from the interactions, foreseen or unforeseen, between the agents/actors. We show that this method reflects the integration of new technologies in a historical case, and apply the same methodology for a possible future technology.

  1. El personaje del loco en el espectáculo medieval y en las cortes principescas del renacimiento

    Directory of Open Access Journals (Sweden)

    Francesc Massip Bonet

    2012-12-01

    Full Text Available El estudio es un paseo por las referencias literarias, archivísticas e iconográficas de fines del Medioevo e inicios del Renacimiento que documentan la actividad del personaje del loco así como del bufón cortesano en las festividades cívicas, agrarias, palaciegas o eclesiásticas, particularmente en su dimensión espectacular o dramática y en el ámbito de la Corona de Aragón.

  2. Analysis of CT-verified loco-regional recurrences after definitive IMRT for HNSCC using site of origin estimation methods

    DEFF Research Database (Denmark)

    Zukauskaite, Ruta; Hansen, Christian R; Brink, Carsten

    2017-01-01

    -regional recurrences had affirmative CT or PET/CT scan. Possible points of origin (POs) of the recurrences were identified on scans by two independent observers, estimated as center of mass and as maximum surface distance. The recurrence position was analyzed in relation to high-dose treatment volume (CTV1) and 95......% of prescription dose. RESULTS: In total, 104 loco-regional recurrences (54 in T-site and 50 in N-site) were identified in 69 patients. Median time to recurrence for the 69 patients was 10 months. No clinically relevant difference was found between the four POs, with standard deviation between POs in x, y and z...

  3. Precise Nanoscale Surface Modification and Coating of Macroscale Objects: Open-Environment in Loco Atomic Layer Deposition on an Automobile.

    Science.gov (United States)

    Mousa, Moataz Bellah M; Oldham, Christopher J; Parsons, Gregory N

    2015-09-09

    The fundamental chemical reaction conditions that define atomic layer deposition (ALD) can be achieved in an open environment on a macroscale surface too large and complex for typical laboratory reactor-based ALD. We describe the concept of in loco ALD using conventional modulated reactant flow through a surface-mounted "ALD delivery head" to form a precise nanoscale Al2O3 film on the window of a parked automobile. Analysis confirms that the processes eliminated ambient water contamination and met other conditions that define ALD growth. Using this tool, we demonstrate open-ambient patterned deposition, metal corrosion protection, and polymer surface modification.

  4. Use of Numerical Simulation at Optimisation of Technological Processes of Cold Bulk Forming

    Directory of Open Access Journals (Sweden)

    Stanislav RUSZ

    2012-06-01

    Full Text Available The paper deals with numerical and physical modelling aimed at optimisation of production technology and designing of manufacturing tools with use of finite-element method. For the topic of cold bulk forming a manufacture of pressed insert, used in industry as a component for damping system for passenger cars, was simulated. It is a rotationally symmetric component, which is subjected to high axial load, and strength and fatigue characteristics of which depend substantially on service life and reliability of the whole damping system. This component was subjected to analysis of distribution of flow stress and deformation intensity at combined extrusion from the viewpoint of their load with use of simulating software Simufact.Forming 10.0. The simulation process ran smoothly, without sudden changes of the shape leading to formation of possible internal defects.

  5. LoCo: a novel main chain scoring function for protein structure prediction based on local coordinates

    Directory of Open Access Journals (Sweden)

    Samudrala Ram

    2011-09-01

    Full Text Available Abstract Background Successful protein structure prediction requires accurate low-resolution scoring functions so that protein main chain conformations that are close to the native can be identified. Once that is accomplished, a more detailed and time-consuming treatment to produce all-atom models can be undertaken. The earliest low-resolution scoring used simple distance-based "contact potentials," but more recently, the relative orientations of interacting amino acids have been taken into account to improve performance. Results We developed a new knowledge-based scoring function, LoCo, that locates the interaction partners of each individual residue within a local coordinate system based only on the position of its main chain N, Cα and C atoms. LoCo was trained on a large set of experimentally determined structures and optimized using standard sets of modeled structures, or "decoys." No structure used to train or optimize the function was included among those used to test it. When tested against 29 other published main chain functions on a group of 77 commonly used decoy sets, our function outperformed all others in Cα RMSD rank of the best-scoring decoy, with statistically significant p-values Conclusions Our function demonstrates an unmatched combination of accuracy, speed, and simplicity and shows excellent promise for protein structure prediction. Broader applications may include protein-protein interactions and protein design.

  6. Design and Simulation of Low Noise Amplifiers at 180nm and 90nm Technologies

    Directory of Open Access Journals (Sweden)

    Fathima Janisha

    2016-11-01

    Full Text Available With continued process scaling, CMOS has become a viable technology for the design of high-performance low noise amplifiers (LNAs in the radio frequency (RF regime. This thesis presents design and simulation of LNA at 180nm and 90nm technology. The LNA function is used to amplify signals without adding noise. The work is done on Cadence Virtuoso platform and the performance parameters like transient response and Noise figure are simulated and plotted. A supply voltage of just 5mV is used here. The noise figure at 180nm is found to be 259.722mdB at 1.04502GHz and The noise figure at 90nm is found to be 183.21mdB at 1.157GHz. 1.04502GHz and 1.157GHz are the peak frequency obtained from the frequency response of the Low noise amplifier. It is observed that the noise figure varies in each technology.

  7. Controlled cooling technology for bar and rod mills -- Computer simulation and operational results

    Energy Technology Data Exchange (ETDEWEB)

    Mauk, P.J.; Kruse, M.; Plociennik, U. [SMS Schloemann-Siemag AG, Dusseldorf (Germany)

    1995-09-01

    The Controlled Cooling Technology (CCT) developed by SMS to simulate the rolling process and automatic control of the water cooling sections is presented. The Controlled Rolling and Cooling Technology (CRCT) model is a key part of the CCT system. It is used to simulate temperature management for the rolling stock on the computer before the actual rolling process takes place. This makes it possible to dispense with extensive rolling tests in the early stages of project planning and to greatly reduce the extent of such tests prior to the start of commercial production in a rolling mill. The CRCT model has been in use at Von Moos Stahl Ag for three years. It demonstrates that, by targeted improvement of the set-up values in both the technology and the plant, it is possible to improve microstructure quality and achieve better geometrical parameters in the rolled products. Also, the results gained with the CCT system in practical operation at the Kia Steel Bar Mill, Kunsan, Korea, are presented.

  8. GIS仿真技术应用研究%Application Research on GIS Simulation Technology

    Institute of Scientific and Technical Information of China (English)

    冯德鸿; 雷帮军; 孙水发; 黄悦华

    2012-01-01

    For a large number of simulations in the macro field like obtaining the exact location information and the time, the GIS technology and the conception of system simulation were introduced in this paper first. Second, some typical domestic and foreign simulation cases based on the main GIS platforms were summarized which includes various main GIS platforms and the application fields. Then the common characteristics of the system simulation based on the GIS technology were summarized. Finally, some prospective study on the development directions of GIS technology and the application area were suggested, including the application that the simulation was changed into the macro field from the micro field in the tradition, the simulation of GIS system was changed into the multi dimentional spatial from the classic two - dimensional spacial and the supporting subject was also changed into the disciplines cross.%针对具有大量地理位置信息与时间信息的宏观领域仿真问题,首先引入了GIS技术与系统仿真的概念,然后概述了国内外主要的GIS平台上进行仿真的典型案例,包括各主流的GIS平台和不同的行业领域,由此总结出应用GIS技术进行系统仿真的一般特点,最后根据GIS技术本身的发展趋势,对G1S仿真技术的发展方向及其应用领域的作了一些前瞻性的研究:仿真的应用领域正从传统的微观领域向空间地理信息等宏观领域方向发展;GIS系统仿真也正从经典的二维信息向空间多维信息方向发展;仿真的支撑学科也正从传统的相关学科转向横向多学科交叉方向发展.

  9. Application of Supercomputer Technologies for Simulation Of Socio-Economic Systems

    Directory of Open Access Journals (Sweden)

    Vladimir Valentinovich Okrepilov

    2015-06-01

    Full Text Available To date, an extensive experience has been accumulated in investigation of problems related to quality, assessment of management systems, modeling of economic system sustainability. The performed studies have created a basis for development of a new research area — Economics of Quality. Its tools allow to use opportunities of model simulation for construction of the mathematical models adequately reflecting the role of quality in natural, technical, social regularities of functioning of the complex socio-economic systems. Extensive application and development of models, and also system modeling with use of supercomputer technologies, on our deep belief, will bring the conducted research of socio-economic systems to essentially new level. Moreover, the current scientific research makes a significant contribution to model simulation of multi-agent social systems and that is not less important, it belongs to the priority areas in development of science and technology in our country. This article is devoted to the questions of supercomputer technologies application in public sciences, first of all, — regarding technical realization of the large-scale agent-focused models (AFM. The essence of this tool is that owing to the power computer increase it has become possible to describe the behavior of many separate fragments of a difficult system, as socio-economic systems are. The article also deals with the experience of foreign scientists and practicians in launching the AFM on supercomputers, and also the example of AFM developed in CEMI RAS, stages and methods of effective calculating kernel display of multi-agent system on architecture of a modern supercomputer will be analyzed. The experiments on the basis of model simulation on forecasting the population of St. Petersburg according to three scenarios as one of the major factors influencing the development of socio-economic system and quality of life of the population are presented in the

  10. Heat Pump Water Heater Technology Assessment Based on Laboratory Research and Energy Simulation Models: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Hudon, K.; Sparn, B.; Christensen, D.; Maguire, J.

    2012-02-01

    This paper explores the laboratory performance of five integrated Heat Pump Water Heaters (HPWHs) across a wide range of operating conditions representative of US climate regions. Laboratory results demonstrate the efficiency of this technology under most of the conditions tested and show that differences in control schemes and design features impact the performance of the individual units. These results were used to understand current model limitations, and then to bracket the energy savings potential for HPWH technology in various US climate regions. Simulation results show that HPWHs are expected to provide significant energy savings in many climate zones when compared to other types of water heaters (up to 64%, including impact on HVAC systems).

  11. Evaluation of practical exercises using an intravenous simulator incorporating virtual reality and haptics device technologies.

    Science.gov (United States)

    Jung, Eun-Young; Park, Dong Kyun; Lee, Young Ho; Jo, Hyun Sook; Lim, Yong Su; Park, Rae Woong

    2012-05-01

    This study confirmed the educational effectiveness of practical exercises (PE) using intravenous (IV) simulators incorporating virtual reality (VR)/haptics (based on the sense of touch) device technologies. First-year nursing students (n=114) were randomly divided into three PE groups: Group A, utilizing a conventional arm model (IV arm); Group B, utilizing a VR/Haptics IV Simulator (IV sim); and Group C, utilizing both the IV arm and IV sim. Group C scored highest on procedures for conducting venipuncture. Group B was more successful in performing injections than Groups A and C. Group C required significantly less time than Group B to complete a venipuncture injection and was faster than Group A, although this difference was not significant. In conclusion, a new paradigm of PE is suggested using both IV sim and IV arm.

  12. [A rapid prototype fabrication method of dental splint based on 3D simulation and technology].

    Science.gov (United States)

    Lin, Yanping; Chen, Xiaojun; Zhang, Shilei; Wang, Chengtao

    2006-04-01

    The conventional design and fabrication of the dental splint (in orthognathic surgery) is based on the preoperative planning and model surgery so this process is of low precision and efficiency. In order to solve the problems and be up to the trend of computer-assisted surgery, we have developed a novel method to design and fabricate the dental splint--computer-generated dental splint, which is based on three-dimensional model simulation and rapid prototype technology. After the surgical planning and simulation of 3D model, we can modify the model to be superior in chewing action (functional) and overall facial appearance (aesthetic). Then, through the Boolean operation of the dental splint blank and the maxillofacial bone model the model of dental splint is formed. At last, the dental splint model is fabricated through rapid prototype machine and applied in clinic. The result indicates that, with the use of this method, the surgical precision and efficiency are improved.

  13. 2014 International Conference on Simulation and Modeling Methodologies, Technologies and Applications

    CERN Document Server

    Ören, Tuncer; Kacprzyk, Janusz; Filipe, Joaquim

    2015-01-01

    The present book includes a set of selected extended papers from the 4th International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2014), held in Vienna, Austria, from 28 to 30 August 2014. The conference brought together researchers, engineers and practitioners interested in methodologies and applications of modeling and simulation. New and innovative solutions are reported in this book. SIMULTECH 2014 received 167 submissions, from 45 countries, in all continents. After a double blind paper review performed by the Program Committee, 23% were accepted as full papers and thus selected for oral presentation. Additional papers were accepted as short papers and posters. A further selection was made after the Conference, based also on the assessment of presentation quality and audience interest, so that this book includes the extended and revised versions of the very best papers of SIMULTECH 2014. Commitment to high quality standards is a major concern of SIMULTEC...

  14. 5th International Conference on Simulation and Modeling Methodologies, Technologies and Applications

    CERN Document Server

    Kacprzyk, Janusz; Ören, Tuncer; Filipe, Joaquim

    2016-01-01

    The present book includes a set of selected extended papers from the 5th International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2015), held in Colmar, France, from 21 to 23 July 2015. The conference brought together researchers, engineers and practitioners interested in methodologies and applications of modeling and simulation. New and innovative solutions are reported in this book. SIMULTECH 2015 received 102 submissions, from 36 countries, in all continents. After a double blind paper review performed by the Program Committee, 19% were accepted as full papers and thus selected for oral presentation. Additional papers were accepted as short papers and posters. A further selection was made after the Conference, based also on the assessment of presentation quality and audience interest, so that this book includes the extended and revised versions of the very best papers of SIMULTECH 2015. Commitment to high quality standards is a major concern of SIMULTECH t...

  15. Simulation and Optimization of Amplitude-adjusting Performance of Crane with Virtual Prototyping Technology

    Institute of Scientific and Technical Information of China (English)

    WU Zhen; YU Meng; DENG Mingxing

    2006-01-01

    In the design of crane, designers often have to study the trajectory of amplitude-adjusting of crane. The traditional methods, illustration and analytics both show their limits. In this paper, the simulation of process of amplitude-adjusting is presented and the optimization is also performed with virtual prototyping technology. From the comparison of original solution and optimal solution, the effectiveness of this technique is testified. On the platform ADAMS/View, the interactive optimization can be performed in a visual, intuitive and credible way, which deserves to be introduced to the design of crane.

  16. Simulation of Cascaded Longitudinal-Space-Charge Amplifier at the Fermilab Accelerator Science & Technology (Fast) Facility

    Energy Technology Data Exchange (ETDEWEB)

    Halavanau, A. [Northern Illinois U.; Piot, P. [Northern Illinois U.

    2015-12-01

    Cascaded Longitudinal Space Charge Amplifiers (LSCA) have been proposed as a mechanism to generate density modulation over a board spectral range. The scheme has been recently demonstrated in the optical regime and has confirmed the production of broadband optical radiation. In this paper we investigate, via numerical simulations, the performance of a cascaded LSCA beamline at the Fermilab Accelerator Science & Technology (FAST) facility to produce broadband ultraviolet radiation. Our studies are carried out using elegant with included tree-based grid-less space charge algorithm.

  17. Endarterectomia carotídea sob bloqueio loco-regional Carotid endarterectomy under locoregional anesthesia

    Directory of Open Access Journals (Sweden)

    Ana Terezinha Guillaumon

    2005-09-01

    Full Text Available OBJETIVO: Os autores objetivam descrever os resultados nas cirurgias de endarterectomia carotídea, utilizando-se anestesia loco-regional, emprego seletivo de shunt e proteção farmacológica intra-operatória. MÉTODO: Foram estudados doentes submetidos à endarterectomia carotídea sob bloqueio loco-regional, no Hospital das Clínicas da Universidade Estadual de Campinas (UNICAMP, no período de março de 1996 a maio de 2004. Este estudo é composto de 119 endarterectomias (108 doentes, sendo 69 doentes (63,8% do sexo masculino e 39 (36,2% do sexo feminino. A idade média foi de 63 anos, variando entre 43 e 83 anos. A indicação da operação foi estenose sintomática em 60 doentes (55,5% e assintomática em 48 (44,5%. Foi realizada avaliação, por imagem, pelo eco-Doppler colorido e arteriografia. RESULTADOS: Foram excluídos do trabalho cinco doentes nos quais foi necessária a conversão para a anestesia geral por intolerância à colocação do clampe carotídeo. Dos 103 doentes submetidos a 114 endarterectomias, utilizamos um shunt em quatro cirurgias (3,5%, em função da intolerância do paciente à colocação do clampe carotídeo durante o ato cirúrgico. Utilizou-se remendo em 19 (16,6% cirurgias. A mortalidade no período pós-operatório imediato ocorreu em três doentes (2,6%, todos em decorrência de acidente vascular cerebral. Um doente (0,87% apresentou acidente vascular isquêmico menor, e um (0,87% doente apresentou síndrome de hiperperfusão, que evoluiu com acidente vascular cerebral hemorrágico. Esse doente foi submetido à drenagem do hematoma cerebral, com recuperação total do déficit neurológico. No pós-operatório tardio, houve reestenose ou oclusão em quatro doentes (5,3%. CONCLUSÃO: A endarterectomia carotídea pode ser realizada com segurança no doente em vigília, utilizando-se o shunt seletivamente, com a utilização de fármaco-proteção cerebral. O bom resultado obtido e a baixa morbimortalidade

  18. Pulmonary function after high-dose chemotherapy with autologous bone marrow transplantation and radiotherapy in patients with advanced loco-regional breast cancer

    NARCIS (Netherlands)

    Dolsma, WV; DeVries, EGE; VanderMark, TW; Sleijfer, DT; Willemse, PHB; VanderGraaf, WTA; Mulder, POM; Szabo, BG; Mulder, NH

    1997-01-01

    Our aim was to study the extent of pulmonary toxicity after high-dose chemotherapy and radiotherapy in breast cancer patients. In a retrospective study the pulmonary symptoms and chest X-rays were analysed before, during and after treatment in 17 patients, treated with loco-regional radiotherapy to

  19. Reconceptualizing the University's Duty to Provide a Safe Learning Environment: A Criticism of the Doctrine of "In Loco Parentis" and the Restatement (Second) of Torts.

    Science.gov (United States)

    Bickel, Robert D.; Lake, Peter F.

    1994-01-01

    Litigation concerning the responsibility of a college or university to provide a safe environment for students is reviewed, focusing on interpretations of the "in loco parentis" doctrine. It is argued that institutions have a duty to not only provide campus security but also enforce a code of civility on campus. (MSE)

  20. In Loco Parentis: Recent Developments in this Legal Doctrine as Applied to the University-Student Relationship in the United States of America, 1965-75.

    Science.gov (United States)

    Conrath, Richard Cranmer

    Is the doctrine of "in loco parentis" a viable legal theory today for describing the relationship between the university and the student in the United States? The student dissent of the 1960's forced both the universities and the courts to reconsider the basic legal nature of the university-student relationship, but there is still…

  1. A pilot study to investigate the role of the 26S proteasome in radiotherapy resistance and loco-regional recurrence following breast conserving therapy for early breast cancer.

    Science.gov (United States)

    Elfadl, Dalia; Hodgkinson, Victoria C; Long, Ervine D; Scaife, Lucy; Drew, Philip J; Lind, Michael J; Cawkwell, Lynn

    2011-08-01

    Breast conserving therapy is a currently accepted method for managing patients with early stage breast cancer. However, approximately 7% of patients may develop loco-regional tumour recurrence within 5 years. We previously reported that expression of the 26S proteasome may be associated with radio-resistance. Here we aimed to analyse the 26S proteasome in a pilot series of early breast cancers and correlate the findings with loco-regional recurrence. Fourteen patients with early breast cancer who developed loco-regional recurrence within 4 years of completing breast conserving therapy were selected according to strict criteria and compared with those from 14 patients who were disease-free at 10 years. Decreased expression of the 26S proteasome was significantly associated with radio-resistance, manifested as the development of a loco-regional recurrence within 4 years of breast conserving therapy (p = 0.018). This small pilot study provides further suggestion that the 26S proteasome may be associated with response to radiotherapy.

  2. The Effectiveness of Information Technology Simulation and Security Awareness Training on U.S Military Personnel in Iraq and Afghanistan

    Science.gov (United States)

    Armstead, Stanley K.

    2017-01-01

    In today's dynamic military environment, information technology plays a crucial role in the support of mission preparedness and operational readiness. This research examined the effectiveness of information technology security simulation and awareness training on U.S. military personnel in Iraq and Afghanistan. Also, the study analyzed whether…

  3. Simulation technology used for risky assessment in deep exploration project in China

    Science.gov (United States)

    jiao, J.; Huang, D.; Liu, J.

    2013-12-01

    Deep exploration has been carried out in China for five years in which various heavy duty instruments and equipments are employed for gravity, magnetic, seismic and electromagnetic data prospecting as well as ultra deep drilling rig established for obtaining deep samples, and so on. The deep exploration is a large and complex system engineering crossing multiple subjects with great investment. It is necessary to employ advanced technical means technology for verification, appraisal, and optimization of geographical prospecting equipment development. To reduce risk of the application and exploration, efficient and allegeable management concept and skills have to be enhanced in order to consolidate management measure and workflow to benefit the ambitious project. Therefore, evidence, prediction, evaluation and related decision strategies have to be taken into accouter simultaneously to meet practical scientific requests and technique limits and extendable attempts. Simulation technique is then proposed as a tool that can be used to carry out dynamic test on actual or imagined system. In practice, it is necessary to combine the simulation technique with the instruments and equipment to accomplish R&D tasks. In this paper, simulation technique is introduced into the R&D process of heavy-duty equipment and high-end engineering project technology. Based on the information provided by a drilling group recently, a digital model is constructed by combination of geographical data, 3d visualization, database management, and visual reality technologies together. It result in push ahead a R&D strategy, in which data processing , instrument application, expected result and uncertainty, and even operation workflow effect environment atmosphere are simulated systematically or simultaneously, in order to obtain an optimal consequence as well as equipment updating strategy. The simulation technology is able to adjust, verify, appraise and optimize the primary plan due to changing in

  4. Advanced seismic imaging technology. Data acquisition (computer simulation of elastic wave propagation); Koseido imaging gijutsu. Data shutoku gijutsu (danseiha simulation)

    Energy Technology Data Exchange (ETDEWEB)

    Tsuru, T. [Tech. Research Center, Japan National Oil Corp., Tokyo (Japan)

    1995-11-10

    Development of software was examined for the purpose of making basic data for an advanced seismic imaging technology by obtaining a seismic exploration data from a complicated underground structural model through a numerical simulation. The result in fiscal 1994 was as follows. A dimensional division difference calculus is superior in the stability and accuracy of numerical calculation and capable of calculating by dividing into one dimensional differences. Attenuation items were added which were due to medium absorbing effect by Maxwell viscoelastic model, and simultaneously a function was added which was capable of dealing with the multi focuses and a group installation of geophones. A pseudospectral method is a kind of difference calculus for numerically solving a partial differential equation, and capable of dividing an underground structural model in lattice and calculating the field on the lattice point. The space direction is differentiated by calculating Fourier series without difference approximation; and, therefore, the number of lattice may be reduced to 2 for the maximum wave length; namely, a lattice interval may be coarsened to reduce calculation time. An improvement was made on the parallel calculation part of the program for two-dimensional analysis developed in the preceding fiscal year, enabling reduction in the calculation time. 4 figs.

  5. Construction Process Simulation and Safety Analysis Based on Building Information Model and 4D Technology

    Institute of Scientific and Technical Information of China (English)

    HU Zhenzhong; ZHANG Jianping; DENG Ziyin

    2008-01-01

    Time-dependent structure analysis theory has been proved to be more accurate and reliable com-pared to commonly used methods during construction. However, so far applications are limited to partial pe-riod and part of the structure because of immeasurable artificial intervention. Based on the building informa-tion model (BIM) and four-dimensional (4D) technology, this paper proposes an improves structure analysis method, which can generate structural geometry, resistance model, and loading conditions automatically by a close interlink of the schedule information, architectural model, and material properties. The method was applied to a safety analysis during a continuous and dynamic simulation of the entire construction process.The results show that the organic combination of the BIM, 4D technology, construction simulation, and safety analysis of time-dependent structures is feasible and practical. This research also lays a foundation for further researches on building lifecycle management by combining architectural design, structure analy-sis, and construction management.

  6. Modeling and Simulation on Axial Piston Pump Based on Virtual Prototype Technology

    Institute of Scientific and Technical Information of China (English)

    ZHANG Bin; XU Bing; XIA Chunlin; YANG Huayong

    2009-01-01

    A particular emphasis is placed on the virtual prototype technology (VPT) of axial piston pump. With this technology it is convenient and flexible to build a complicated 3D virtual based on real physical model. The actual kinematics pairs of the parts were added on the model. The fluid characters were calculated by hydraulic software. The shape of the parts, the flexible body of parts, etc were improved in this prototype. So the virtual prototype of piston pump can work in computer like a real piston pump, and the flow ripple, pressure pulsation, motion principle, stress of parts, etc can be investigated. The development of the VPT is introduced at the beginning, and the modeling process of the virtual prototype is explained. Then a special emphasis is laid on the relationship between the dynamics model and the hydraulic model, and the simulations on the flow ripple, pressure pulsation, motion principle, the stress and strain distribution of the middle shaft and piston are operated. Finally, the advantages and disadvantages of the VPT are discussed. The improved virtual prototype of piston pump more tally with the real situation and the VPT has a great potential in simulation on hydraulic components.

  7. Learning and Treatment of Anaphylaxis by Laypeople: A Simulation Study Using Pupilar Technology

    Directory of Open Access Journals (Sweden)

    Felipe Fernandez-Mendez

    2017-01-01

    Full Text Available An anaphylactic shock is a time-critical emergency situation. The decision-making during emergencies is an important responsibility but difficult to study. Eye-tracking technology allows us to identify visual patterns involved in the decision-making. The aim of this pilot study was to evaluate two training models for the recognition and treatment of anaphylaxis by laypeople, based on expert assessment and eye-tracking technology. A cross-sectional quasi-experimental simulation study was made to evaluate the identification and treatment of anaphylaxis. 50 subjects were randomly assigned to four groups: three groups watching different training videos with content supervised by sanitary personnel and one control group who received face-to-face training during paediatric practice. To evaluate the learning, a simulation scenario represented by an anaphylaxis’ victim was designed. A device capturing eye movement as well as expert valuation was used to evaluate the performance. The subjects that underwent paediatric face-to-face training achieved better and faster recognition of the anaphylaxis. They also used the adrenaline injector with better precision and less mistakes, and they needed a smaller number of visual fixations to recognise the anaphylaxis and to make the decision to inject epinephrine. Analysing the different video formats, mixed results were obtained. Therefore, they should be tested to evaluate their usability before implementation.

  8. A comparison of renewable energy technologies using two simulation softwares: HOMER and RETScreen

    Science.gov (United States)

    Ramli, Mohd Sufian; Wahid, Siti Sufiah Abd; Hassan, Khairul Kamarudin

    2017-08-01

    This paper concerns on modelling renewable energy technologies including PV standalone system (PVSS) and wind standalone system (WSS) as well as PV-wind hybrid system (PVWHS). To evaluate the performance of all power system configurations in term of economic analysis and optimization, simulation tools called HOMER and RETScreen are used in this paper. HOMER energy modeling software is a powerful tool for designing and analyzing hybrid power systems, which contains a mix of conventional generators, wind turbines, solar photovoltaic's, hydropower, batteries, and other inputs. RETScreen uses a Microsoft Excel-based spreadsheet model that consists of a set of workbooks which calculates the annual average energy flows with adjustment factors to account for temporal effects such as solar-load coincidence. Sizes of equipments are calculated and inserted as inputs to HOMER and RETScreen. The result obtained are analyzed and discussed. The cost per kWh to generate electricity using the PVSS system to supply the average demand of 8.4 kWh/day ranges between RM 1.953/kWh to RM 3.872/kWh. It has been found that the PVSS gives the lowest cost of energy compared to the other proposed two technologies that have been simulated by using HOMER and RETScreen.

  9. Simulated Lunar Testing of Metabolic Heat Regenerated Temperature Swing Adsorption Technology

    Science.gov (United States)

    Padilla, Sebastian A.; Bower, Chad; Iacomini, Christie S.; Paul, H.

    2011-01-01

    Metabolic heat regenerated Temperature Swing Adsorption (MTSA) technology is being developed for thermal and carbon dioxide (CO2) control for a Portable Life Support System (PLSS), as well as water recycling. An Engineering Development Unit (EDU) of the MTSA subassembly was designed and assembled for optimized Martian operations, but also meets system requirements for lunar operations. For lunar operations the MTSA sorption cycle is driven via a vacuum swing between suit ventilation loop pressure and lunar vacuum. The focus of this effort is operations and testing in a simulated lunar environment. This environment was simulated in Paragon s EHF vacuum chamber. The objective of this testing was to evaluate the full cycle performance of the MTSA Subassembly EDU, and to assess CO2 loading and pressure drop of the wash coated aluminum reticulated foam sorbent bed. The lunar testing proved out the feasibility of pure vacuum swing operation, making MTSA a technology that can be tested and used on the Moon prior to going to Mars. Testing demonstrated better than expected CO2 loading on the sorbent and nearly replicates the equilibrium data from the sorbent manufacturer. This had not been achieved in any of the previous sorbent loading tests performed by Paragon. Subsequently, the increased performance of the sorbent bed design indicates future designs will require less mass and volume than the current EDU rendering MTSA as very competitive for Martian PLSS applications.

  10. Prognostic impact of epidermal growth factor receptor (EGFR expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer

    Directory of Open Access Journals (Sweden)

    Ychou Marc

    2005-06-01

    Full Text Available Abstract Background Epidermal growth factor receptor (EGFR represents a major target for current radiosensitizing strategies. We wished to ascertain whether a correlation exists between the expression of EGFR and treatment outcome in a group of patients with rectal adenocarcinoma who had undergone preoperative radiotherapy (RT. Methods Within a six-year period, 138 patients underwent preoperative radiotherapy and curative surgery for rectal cancer (UICC stages II-III at our institute. Among them, 77 pretherapeutic tumor biopsies were available for semi-quantitative immunohistochemical investigation evaluating the intensity and the number (extent of tumor stained cells. Statistical analyses included Cox regression for calculating risk ratios of survival endpoints and logistic regression for determining odds ratios for the development of loco-regional recurrences. Results Median age was 64 years (range: 30–88. Initial staging showed 75% and 25% stage II and III tumors, respectively. RT consisted of 44-Gy pelvic irradiation in 2-Gy fractions using 18-MV photons. In 25 very low-rectal-cancer patients the primary tumor received a boost dose of up to 16 Gy for a sphincter-preservation approach. Concomitant chemotherapy was used in 17% of the cases. All patients underwent complete total mesorectal resection. Positive staining (EGFR+ was observed in 43 patients (56%. Median follow-up was 36 months (range: 6–86. Locoregional recurrence rates were 7 and 20% for EGFR extent inferior and superior to 25%, respectively. The corresponding locoregional recurrence-free survival rate at two years was 94% (95% confidence interval, CI, 92–98% and 84% (CI 95%, 58–95%, respectively (P = 0.06. Multivariate analyses showed a significant correlation between the rate of loco-regional recurrence and three parameters: EGFR extent superior to 25% (hazard ratio = 7.18, CI 95%, 1.17–46, P = 0.037, rectal resection with microscopic residue (hazard ratio = 6.92, CI 95

  11. Using clinical and computer simulations to reason about the impact of context on system safety and technology-induced error.

    Science.gov (United States)

    Kushniruk, Andre W; Borycki, Elizabeth M; Anderson, James; Anderson, Marilyn; Nicoll, James; Kannry, Joseph

    2013-01-01

    This paper describes how simulations can be used to reason about the impact of user interface design features in exploring the effect of different contexts of use on the occurrence of technology-induced errors. The paper describes our approach in several phases, using an example from the analysis of technology-induced errors in medication administration. In the initial phase a clinical simulation is conducted to gather baseline data on the occurrence of technology-induced error using the technology under study. In this phase of the study, data arising from the clinical simulation are collected and then analyzed using qualitative and quantitative approaches to assess the relationship between aspects of interface design (i.e. usability problems) and rates of technology-induced error. In the next phase, the base rates for error associated with specific types of usability problems (from the initial phase) form the input into computer-based mathematical simulations. This approach links clinical simulations with computer-based simulations and demonstrates the potential impact of aspects of interface design and contextual factors upon medical error along with the implications for correcting interface design issues.

  12. Integration of environmental simulation models with satellite remote sensing and geographic information systems technologies: case studies

    Science.gov (United States)

    Steyaert, Louis T.; Loveland, Thomas R.; Brown, Jesslyn F.; Reed, Bradley C.

    1993-01-01

    Environmental modelers are testing and evaluating a prototype land cover characteristics database for the conterminous United States developed by the EROS Data Center of the U.S. Geological Survey and the University of Nebraska Center for Advanced Land Management Information Technologies. This database was developed from multi temporal, 1-kilometer advanced very high resolution radiometer (AVHRR) data for 1990 and various ancillary data sets such as elevation, ecological regions, and selected climatic normals. Several case studies using this database were analyzed to illustrate the integration of satellite remote sensing and geographic information systems technologies with land-atmosphere interactions models at a variety of spatial and temporal scales. The case studies are representative of contemporary environmental simulation modeling at local to regional levels in global change research, land and water resource management, and environmental simulation modeling at local to regional levels in global change research, land and water resource management and environmental risk assessment. The case studies feature land surface parameterizations for atmospheric mesoscale and global climate models; biogenic-hydrocarbons emissions models; distributed parameter watershed and other hydrological models; and various ecological models such as ecosystem, dynamics, biogeochemical cycles, ecotone variability, and equilibrium vegetation models. The case studies demonstrate the important of multi temporal AVHRR data to develop to develop and maintain a flexible, near-realtime land cover characteristics database. Moreover, such a flexible database is needed to derive various vegetation classification schemes, to aggregate data for nested models, to develop remote sensing algorithms, and to provide data on dynamic landscape characteristics. The case studies illustrate how such a database supports research on spatial heterogeneity, land use, sensitivity analysis, and scaling issues

  13. Simulation Based Optimization of Complex Monolithic Composite Structures Using Cellular Core Technology

    Science.gov (United States)

    Hickmott, Curtis W.

    Cellular core tooling is a new technology which has the capability to manufacture complex integrated monolithic composite structures. This novel tooling method utilizes thermoplastic cellular cores as inner tooling. The semi-rigid nature of the cellular cores makes them convenient for lay-up, and under autoclave temperature and pressure they soften and expand providing uniform compaction on all surfaces including internal features such as ribs and spar tubes. This process has the capability of developing fully optimized aerospace structures by reducing or eliminating assembly using fasteners or bonded joints. The technology is studied in the context of evaluating its capabilities, advantages, and limitations in developing high quality structures. The complex nature of these parts has led to development of a model using the Finite Element Analysis (FEA) software Abaqus and the plug-in COMPRO Common Component Architecture (CCA) provided by Convergent Manufacturing Technologies. This model utilizes a "virtual autoclave" technique to simulate temperature profiles, resin flow paths, and ultimately deformation from residual stress. A model has been developed simulating the temperature profile during curing of composite parts made with the cellular core technology. While modeling of composites has been performed in the past, this project will look to take this existing knowledge and apply it to this new manufacturing method capable of building more complex parts and develop a model designed specifically for building large, complex components with a high degree of accuracy. The model development has been carried out in conjunction with experimental validation. A double box beam structure was chosen for analysis to determine the effects of the technology on internal ribs and joints. Double box beams were manufactured and sectioned into T-joints for characterization. Mechanical behavior of T-joints was performed using the T-joint pull-off test and compared to traditional

  14. Testing and Results of Human Metabolic Simulation Utilizing Ultrasonic Nebulizer Technology for Water Vapor Generation

    Science.gov (United States)

    Stubbe, Matthew; Curley, Su

    2010-01-01

    Life support technology must be evaluated thoroughly before ever being implemented into a functioning design. A major concern during that evaluation is safety. The ability to mimic human metabolic loads allows test engineers to evaluate the effectiveness of new technologies without risking injury to any actual humans. The main function of most life support technologies is the removal of carbon dioxide (CO2) and water (H2O) vapor. As such any good human metabolic simulator (HMS) will mimic the human body s ability to produce these items. Introducing CO2 into a test chamber is a very straightforward process with few unknowns so the focus of this particular new HMS design was on the much more complicated process of introducing known quantities of H2O vapor on command. Past iterations of the HMS have utilized steam which is very hard to keep in vapor phase while transporting and injecting into a test chamber. Also steam adds large quantities of heat to any test chamber, well beyond what an actual human does. For the new HMS an alternative approach to water vapor generation was designed utilizing ultrasonic nebulizers as a method for creating water vapor. Ultrasonic technology allows water to be vibrated into extremely tiny pieces (2-5 microns) and evaporate without requiring additional heating. Doing this process inside the test chamber itself allows H2O vapor generation without the unwanted heat and the challenging process of transporting water vapor. This paper presents the design details as well as results of all initial and final acceptance system testing. Testing of the system was performed at a range of known human metabolic rates in both sea-level and reduced pressure environments. This multitude of test points fully defines the systems capabilities as they relate to actual environmental systems testing.

  15. Ocean Acidification Disrupts Prey Responses to Predator Cues but Not Net Prey Shell Growth in Concholepas concholepas (loco)

    Science.gov (United States)

    Manríquez, Patricio H.; Jara, María Elisa; Mardones, María Loreto; Navarro, Jorge M.; Torres, Rodrigo; Lardies, Marcos A.; Vargas, Cristian A.; Duarte, Cristian; Widdicombe, Stephen; Salisbury, Joseph; Lagos, Nelson A.

    2013-01-01

    Background Most research on Ocean Acidification (OA) has largely focused on the process of calcification and the physiological trade-offs employed by calcifying organisms to support the building of calcium carbonate structures. However, there is growing evidence that OA can also impact upon other key biological processes such as survival, growth and behaviour. On wave-swept rocky shores the ability of gastropods to self-right after dislodgement, and rapidly return to normal orientation, reduces the risk of predation. Methodology/Principal Findings The impacts of OA on this self-righting behaviour and other important parameters such as growth, survival, shell dissolution and shell deposition in Concholepas concholepas (loco) were investigated under contrasting pCO2 levels. Although no impacts of OA on either growth or net shell calcification were found, the results did show that OA can significantly affect self-righting behaviour during the early ontogeny of this species with significantly faster righting times recorded for individuals of C. concholepas reared under increased average pCO2 concentrations (± SE) (716±12 and 1036±14 µatm CO2) compared to those reared at concentrations equivalent to those presently found in the surface ocean (388±8 µatm CO2). When loco were also exposed to the predatory crab Acanthocyclus hassleri, righting times were again increased by exposure to elevated CO2, although self-righting times were generally twice as fast as those observed in the absence of the crab. Conclusions and Significance These results suggest that self-righting in the early ontogeny of C. concholepas will be positively affected by pCO2 levels expected by the end of the 21st century and beginning of the next one. However, as the rate of self-righting is an adaptive trait evolved to reduce lethal predatory attacks, our result also suggest that OA may disrupt prey responses to predators in nature. PMID:23844231

  16. Regional PET/CT after water gastric inflation for evaluating loco-regional disease of gastric cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Soo Jin, E-mail: suji76@hanmail.net [Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); Lee, Won Woo, E-mail: wwlee@snubh.org [Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); Institute of Radiation Medicine, Medical Research Center, Seoul National University (Korea, Republic of); Yoon, Hai-Jeon, E-mail: punsu07@naver.com [Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); Lee, Ho-Young, E-mail: debobkr@gmail.com [Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); Lee, Kyoung Ho, E-mail: kholeemail@gmail.com [Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); Institute of Radiation Medicine, Medical Research Center, Seoul National University (Korea, Republic of); Kim, Young Hoon, E-mail: yhkrad@gmail.com [Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); Institute of Radiation Medicine, Medical Research Center, Seoul National University (Korea, Republic of); Park, Do Joong, E-mail: djpark@snubh.org [Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); Kim, Hyung-Ho, E-mail: hhkim@snubh.org [Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine (Korea, Republic of); So, Young, E-mail: youngso@kuh.ac.kr [Department of Nuclear Medicine, Konkuk University School of Medicine (Korea, Republic of); and others

    2013-06-15

    Objective: We aimed to improve diagnostic accuracy of {sup 18}F-fluoro-2-deoxyglucose (FDG) PET/CT for gastric cancer with water gastric inflation. Materials and methods: 44 gastric cancer patients (M:F = 30:14, age ± std = 62.1 ± 14.5y) were enrolled before surgery. Fifty minutes after injection of FDG (0.14 mCi/kg body weight), whole body PET/CT was performed first and then regional PET/CT over gastric area was obtained 80 min post FDG injection after water gastric inflation. Diagnostic accuracies for loco-regional lesions were compared between whole body and regional PET/CT. Results: 48 primary tumors (23 EGC and 25 AGC) and 348 LN stations (61 metastatic and 287 benign) in 44 patients were investigated. Primary tumor sensitivity of whole body PET/CT (50% = 24/48) was significantly improved by regional PET/CT (75% = 36/48, p < 0.005). Sensitivity of whole body PET/CT (24.6% = 15/61) for LN metastasis was also significantly improved by regional PET/CT (36.1% = 22/61, p < 0.01), whereas specificity of whole body PET/CT (99.3% = 285/287) was not compromised by regional PET/CT (98.3% = 282/287, p > 0.05). Higher primary tumor FDG uptake in regional PET/CT indicated shorter progress-free survival (p = 0.0003). Conclusion: Diagnostic accuracy of whole body PET/CT for loco-regional disease of gastric cancer could be significantly improved by regional PET/CT after water gastric inflation and prognosis could be effectively predicted by primary tumor FDG uptake in regional PET/CT.

  17. Technology advancement for the ASCENDS mission using the ASCENDS CarbonHawk Experiment Simulator (ACES)

    Science.gov (United States)

    Obland, M. D.; Antill, C.; Browell, E. V.; Campbell, J. F.; CHEN, S.; Cleckner, C.; Dijoseph, M. S.; Harrison, F. W.; Ismail, S.; Lin, B.; Meadows, B. L.; Mills, C.; Nehrir, A. R.; Notari, A.; Prasad, N. S.; Kooi, S. A.; Vitullo, N.; Dobler, J. T.; Bender, J.; Blume, N.; Braun, M.; Horney, S.; McGregor, D.; Neal, M.; Shure, M.; Zaccheo, T.; Moore, B.; Crowell, S.; Rayner, P. J.; Welch, W.

    2013-12-01

    The ASCENDS CarbonHawk Experiment Simulator (ACES) is a NASA Langley Research Center project funded by NASA's Earth Science Technology Office that seeks to advance technologies critical to measuring atmospheric column carbon dioxide (CO2) mixing ratios in support of the NASA Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission. The technologies being advanced are: (1) multiple transmitter and telescope-aperture operations, (2) high-efficiency CO2 laser transmitters, (3) a high bandwidth detector and transimpedance amplifier (TIA), and (4) advanced algorithms for cloud and aerosol discrimination. The instrument architecture is being developed for ACES to operate on a high-altitude aircraft, and it will be directly scalable to meet the ASCENDS mission requirements. The above technologies are critical for developing an airborne simulator and spaceborne instrument with lower platform consumption of size, mass, and power, and with improved performance. This design employs several laser transmitters and telescope-apertures to demonstrate column CO2 retrievals with alignment of multiple laser beams in the far-field. ACES will transmit five laser beams: three from commercial lasers operating near 1.57-microns, and two from the Exelis atmospheric oxygen (O2) fiber laser amplifier system operating near 1.26-microns. The Master Oscillator Power Amplifier at 1.57-microns measures CO2 column concentrations using an Integrated-Path Differential Absorption (IPDA) lidar approach. O2 column amounts needed for calculating the CO2 mixing ratio will be retrieved using the Exelis laser system with a similar IPDA approach. The three aperture telescope design was built to meet the constraints of the Global Hawk high-altitude unmanned aerial vehicle (UAV). This assembly integrates fiber-coupled transmit collimators for all of the laser transmitters and fiber-coupled optical signals from the three telescopes to the aft optics and detector package. The detector

  18. Simulated human patients and patient-centredness: The uncanny hybridity of nursing education, technology, and learning to care.

    Science.gov (United States)

    Ireland, Aileen V

    2017-01-01

    Positioned within a hybrid of the human and technology, professional nursing practice has always occupied a space that is more than human. In nursing education, technology is central in providing tools with which practice knowledge is mobilized so that students can safely engage with simulated human patients without causing harm to real people. However, while there is an increased emphasis on deploying these simulated humans as emissaries from person-centred care to demonstrate what it is like to care for real humans, the nature of what is really going on in simulation-what is real and what is simulated-is very rarely discussed and poorly understood. This paper explores how elements of postcolonial critical thought can aid in understanding the challenges of educating nurses to provide person-centred care within a healthcare culture that is increasingly reliant on technology. Because nursing education is itself a hybrid of real and simulated practice, it provides an appropriate case study to explore the philosophical question of technology in healthcare discourse, particularly as it relates to the relationship between the human patient and its uncanny simulated double. Drawing on postcolonial elements such as the uncanny, diaspora, hybridity, and créolité, the hybrid conditions of nursing education are examined in order to open up new possibilities of thinking about how learning to care is entangled with this technological space to assist in shaping professional knowledge of person-centred care. Considering these issues through a postcolonial lens opens up questions about the nature of the difficulty in using simulated human technologies in clinical education, particularly with the paradoxical aim of providing person-centred care within a climate that increasingly characterized as posthuman. © 2016 John Wiley & Sons Ltd.

  19. 4D Design and Simulation Technologies and Process Design Patterns to Support Lean Construction Methods

    Institute of Scientific and Technical Information of China (English)

    Manfred Breit; Manfred Vogel; Fritz H(a)ubi; Fabian M(a)rki; Micheal Raps

    2008-01-01

    The objective of this ongoing joint research program is to determine how 3D/4D modeling, simula- tion and visualization of Products (buildings), Organizations and Processes (POP) can support lean con- struction. Initial findings suggest that Process Design Pattern may have the potential to intuitively support ICT based lean construction. We initiated a "Process Archeology" in order to reveal the requirements for tools that can support the planning, simulation and control of lean construction methods. First findings show that existing tools provide only limited support and therefore, we started to develop new methodologies and technologies to overcome these shortcomings. Through the introduction of Process Design Patterns, we in- tent to establish process thinking in the interdisciplinary POP design. Optimized construction processes may be synthesized with semi-automatic methods by applying Process Design Pattems on building structures. By providing process templates that integrate problem solution and expert knowledge, Process Design Pat- tems may have the potential to ensure high quality process models.

  20. Microwave technology for localization of traumatic intracranial bleedings-a numerical simulation study.

    Science.gov (United States)

    Candefjord, Stefan; Winges, Johan; Yu, Yinan; Rylander, Thomas; McKelvey, Tomas

    2013-01-01

    Traumatic brain injury (TBI) is a major public health problem worldwide. Intracranial bleedings represents the most serious complication of TBI and need to be surgically evacuated promptly to save lives and mitigate injury. Microwave technology (MWT) is promising as a complement to computed tomography (CT) to be used in road and air ambulances for early detection of intracranial bleedings. In this study, we perform numerical simulations to investigate if a classification algorithm based on singular value decomposition can distinguish between bleedings at different positions adjacent to the skull bone for a similar but simplified problem. The classification accuracy is 94-100% for all classes, a result that encourages us to pursue our efforts with MWT for more realistic scenarios. This indicates that MWT has potential for localizing a detected bleeding, which would increase the diagnostic value of this technique.

  1. The Nuclear Energy Advanced Modeling and Simulation Enabling Computational Technologies FY09 Report

    Energy Technology Data Exchange (ETDEWEB)

    Diachin, L F; Garaizar, F X; Henson, V E; Pope, G

    2009-10-12

    In this document we report on the status of the Nuclear Energy Advanced Modeling and Simulation (NEAMS) Enabling Computational Technologies (ECT) effort. In particular, we provide the context for ECT In the broader NEAMS program and describe the three pillars of the ECT effort, namely, (1) tools and libraries, (2) software quality assurance, and (3) computational facility (computers, storage, etc) needs. We report on our FY09 deliverables to determine the needs of the integrated performance and safety codes (IPSCs) in these three areas and lay out the general plan for software quality assurance to meet the requirements of DOE and the DOE Advanced Fuel Cycle Initiative (AFCI). We conclude with a brief description of our interactions with the Idaho National Laboratory computer center to determine what is needed to expand their role as a NEAMS user facility.

  2. [Method for environmental management in paper industry based on pollution control technology simulation].

    Science.gov (United States)

    Zhang, Xue-Ying; Wen, Zong-Guo

    2014-11-01

    To evaluate the reduction potential of industrial water pollutant emissions and to study the application of technology simulation in pollutant control and environment management, an Industrial Reduction Potential Analysis and Environment Management (IRPAEM) model was developed based on coupling of "material-process-technology-product". The model integrated bottom-up modeling and scenario analysis method, and was applied to China's paper industry. Results showed that under CM scenario, the reduction potentials of waster water, COD and ammonia nitrogen would reach 7 x 10(8) t, 39 x 10(4) t and 0.3 x 10(4) t, respectively in 2015, 13.8 x 10(8) t, 56 x 10(4) t and 0.5 x 10(4) t, respectively in 2020. Strengthening the end-treatment would still be the key method to reduce emissions during 2010-2020, while the reduction effect of structure adjustment would be more obvious during 2015-2020. Pollution production could basically reach the domestic or international advanced level of clean production in 2015 and 2020; the index of wastewater and ammonia nitrogen would basically meet the emission standards in 2015 and 2020 while COD would not.

  3. The simulation of the half-dry stroke based on the force feedback technology

    Science.gov (United States)

    Guo, Chao; Hou, Zeng-xuan; Zheng, Shuan-zhu; Yang, Guang-qing

    2017-02-01

    A novel stroke simulation method of the Half-dry style of Chinese calligraphy based on the force feedback technology is proposed for the virtual painting. Firstly, according to the deformation of the brush when the force is exerted on it, the brush footprint between the brush and paper is calculated. The complete brush stroke is obtained by superimposing brush footprints along the painting direction, and the dynamic painting of the brush stroke is implemented. Then, we establish the half-dry texture databases and propose the concept of half-dry value by researching the main factors that affect the effects of the half-dry stroke. In the virtual painting, the half-dry texture is mapped into the stroke in real time according to the half-dry value and painting technique. A technique of texture blending based on the KM model is applied to avoid the seams while texture mapping. The proposed method has been successfully applied to the virtual painting system based on the force feedback technology. In this system, users can implement the painting in real time with a Phantom Desktop haptic device, which can effectively enhance reality to users.

  4. Material Protection, Accounting, and Control Technologies (MPACT): Modeling and Simulation Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Cipiti, Benjamin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dunn, Timothy [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Durbin, Samual [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Durkee, Joe W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); England, Jeff [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, Robert [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Ketusky, Edward [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Li, Shelly [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lindgren, Eric [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Meier, David [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Miller, Michael [Idaho National Lab. (INL), Idaho Falls, ID (United States); Osburn, Laura Ann [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pereira, Candido [Argonne National Lab. (ANL), Argonne, IL (United States); Rauch, Eric Benton [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Scaglione, John [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Scherer, Carolynn P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sprinkle, James K. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Yoo, Tae-Sic [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-05

    The development of sustainable advanced nuclear fuel cycles is a long-term goal of the Office of Nuclear Energy’s (DOE-NE) Fuel Cycle Technologies program. The Material Protection, Accounting, and Control Technologies (MPACT) campaign is supporting research and development (R&D) of advanced instrumentation, analysis tools, and integration methodologies to meet this goal. This advanced R&D is intended to facilitate safeguards and security by design of fuel cycle facilities. The lab-scale demonstration of a virtual facility, distributed test bed, that connects the individual tools being developed at National Laboratories and university research establishments, is a key program milestone for 2020. These tools will consist of instrumentation and devices as well as computer software for modeling. To aid in framing its long-term goal, during FY16, a modeling and simulation roadmap is being developed for three major areas of investigation: (1) radiation transport and sensors, (2) process and chemical models, and (3) shock physics and assessments. For each area, current modeling approaches are described, and gaps and needs are identified.

  5. Simulation study of a novel 3D SPAD pixel in an advanced FD-SOI technology

    Science.gov (United States)

    Vignetti, M. M.; Calmon, F.; Lesieur, P.; Savoy-Navarro, A.

    2017-02-01

    In this paper, a novel SPAD architecture implemented in a Fully-Depleted Silicon-On-Insulator (SOI) CMOS technology is presented. Thanks to its intrinsic vertical 3D structure, the proposed solution is expected to allow further scaling of the pixel size while ensuring high fill factors. Moreover the pixel and the detector electronics can benefit of the well-known advantages brought by SOI technology with respect to bulk CMOS, such as higher speed and lower power consumption. TCAD simulations based on realistic process parameters and dedicated post-processing analysis are carried out in order to optimize and validate the avalanche diode architecture for an optimal electric field distribution in the device but also to extract the main parameters of the SPAD, such as the breakdown voltage, the avalanche triggering probability, the dark count rate and the photon detection probability. A comparison between the efficiency in back-side and front-side approaches is carried out with a particular focus on time-of-flight applications.

  6. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming Analysis, Simulation and Engineering Applications

    CERN Document Server

    Hu, Ping; Liu, Li-zhong; Zhu, Yi-guo

    2013-01-01

    Over the last 15 years, the application of innovative steel concepts in the automotive industry has increased steadily. Numerical simulation technology of hot forming of high-strength steel allows engineers to modify the formability of hot forming steel metals and to optimize die design schemes. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming focuses on hot and cold forming theories, numerical methods, relative simulation and experiment techniques for high-strength steel forming and die design in the automobile industry. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming introduces the general theories of cold forming, then expands upon advanced hot forming theories and simulation methods, including: • the forming process, • constitutive equations, • hot boundary constraint treatment, and • hot forming equipment and experiments. Various calculation methods of cold and hot forming, based on the authors’ experience in commercial CAE software f...

  7. Use of Web 2.0 Technologies for Public Outreach on a Simulated Mars Mission

    Science.gov (United States)

    Shiro, B.; Palaia, J.; Ferrone, K.

    2009-12-01

    Recent advances in social media and internet communications have revolutionized the ways people interact and disseminate information. Astronauts are already starting to take advantage of these tools by blogging and tweeting from space, and almost all NASA missions now have presences on the major social networking sites. One priority for future human explorers on Mars will be communicating their experiences to the people back on Earth. During July 2009, a six-member crew of volunteers carried out a simulated Mars mission at the Flashline Mars Arctic Research Station (FMARS) on Devon Island in the Canadian Arctic. Living in a habitat, conducting EVAs wearing spacesuits, and observing communication delays with “Earth,” the crew endured restrictions similar to those that will be faced by future human Mars explorers. Throughout the expedition, crewmembers posted regular blog entries, reports, photos, videos, and updates to their website and social media outlets Twitter, Facebook, YouTube, and Picasa Web Albums. During the sixteen EVAs of their field science research campaign, FMARS crewmembers collected GPS track information and took geotagged photos using GPS-enabled cameras. They combined their traverse GPS tracks with photo location information into KML/KMZ files that website visitors can view in Google Maps or Google Earth. Although the crew observed a strict 20-minute communication delay with “Earth” to simulate a real Mars mission, they broke this rule to conduct four very successful live webcasts with student groups using Skype since education and public outreach were important objectives of the endeavor. This presentation will highlight the use of Web 2.0 technologies for public outreach during the simulated Mars expedition and the implications for other remote scientific journeys. The author embarks on a "rover" to carry out an EVA near the FMARS Habitat. The satellite dish to the right of the structure was used for all communications with the remote

  8. The application of additive technologies in creation a medical simulator-trainer of the human head operating field

    Science.gov (United States)

    Kashapov, L. N.; Kashapov, N. F.; Kashapov, R. N.; Pashaev, B. Y.

    2016-06-01

    The aim of the work was to determine the possible application of additive manufacturing technology during the manufacturing process as close as possible to reality of medical simulator-trainers. In work were used some additive manufacturing technologies: selective laser sintering (SLS), fused deposition modeling (FDM), binder Jetting. As a result, a prototype of simulator-trainer of the human head operating field, which based on the CT real patient, was manufactured and conducted its tests. It was found that structure, which is obtained with the use of 3D-printers ProJet 160, most appropriate and closest to the real properties of the bone.

  9. Hardware-in-the-loop simulation technology of wide-band radar targets based on scattering center model

    Institute of Scientific and Technical Information of China (English)

    Huang Hao; Pan Minghai; Lu Zhijun

    2015-01-01

    Hardware-in-the-loop (HWIL) simulation technology can verify and evaluate the radar by simulating the radio frequency environment in an anechoic chamber. The HWIL simulation technology of wide-band radar targets can accurately generate wide-band radar target echo which stands for the radar target scattering characteristics and pulse modulation of radar transmitting sig-nal. This paper analyzes the wide-band radar target scattering properties first. Since the responses of target are composed of many separate scattering centers, the target scattering characteristic is restructured by scattering centers model. Based on the scattering centers model of wide-band radar target, the wide-band radar target echo modeling and the simulation method are discussed. The wide-band radar target echo is reconstructed in real-time by convoluting the transmitting signal to the target scattering parameters. Using the digital radio frequency memory (DRFM) system, the HWIL simulation of wide-band radar target echo with high accuracy can be actualized. A typical wide-band radar target simulation is taken to demonstrate the preferable simulation effect of the reconstruction method of wide-band radar target echo. Finally, the radar target time-domain echo and high-resolution range profile (HRRP) are given. The results show that the HWIL simulation gives a high-resolution range distribution of wide-band radar target scattering centers.

  10. Design and simulation of cellular nonlinear networks using single-electron tunneling transistor technology

    Science.gov (United States)

    Gerousis, Costa P.

    It is currently predicted that semiconductor device scaling will end at the 22-nm device feature size (7 nm physical channel length) according to the International Technology Roadmap for Semiconductors. The main challenge is then to develop innovative technologies that will extend the scaling beyond roadmap projection. Any new technology must be well matched with complementary metal oxide semiconductor (CMOS) technology and scaleable beyond CMOS scaling projections and must provide low-power high-speed signal processing. Nanotechnology will become an appealing option for developing devices for integrated circuits with dimensions and performances well beyond roadmap predictions. Such devices, based on the controllable transfer of charge between dots or 'islands', can take advantage of the quantum mechanical effects, such as tunneling and energy quantization, which would normally occur at the nanometer scale. An outstanding challenge is in arranging such nanodevices in new architectures that can be integrated on a single chip. In particular, locally interconnected architectures are believed to be necessary to alleviate the problems associated with increasing interconnect length and complexity in ultra-dense circuits. The goal of this work is to investigate the use of nanoelectronic structures in cellular non-linear network (CNN) architectures for potential application in future high-density and low-power CMOS-nanodevice hybrid circuits. The operation of the single-electron tunneling (SET) transistor is first reviewed, followed by a discussion of simple CNN linear architectures using a SET inverter topology as the basis for the non-linear transfer characteristics for individual cells to be used in analog processing arrays for image-processing applications. The basic SET CNN cell acts as a summing node that is capacitively coupled to the inputs and outputs of nearest neighbor cells. Monte Carlo simulation results are used to show CNN-like behavior in attempting to

  11. Progress of Radioactive Waste Treatment Technology:Study on Alteration of Simulated HLW Glass under Simulated Geological Disposal Condition

    Institute of Scientific and Technical Information of China (English)

    HUA; Xiao-hui; WANG; Lei; YOU; Xin-feng; ZHENG; Wen-jun; YANG; Lin-yue; LI; Yu-song; ZHENG; Yu; LI; Teng; ZHANG; Zhen-tao

    2015-01-01

    1/200 scale simulated disposal experimental device was set up in 2013 and operated from 2014,in which ground water penetrated host rock,buffer materials,container materials and simulated HLW glass.The leaching velocity,alteration of HLW glass and corrosion of container materials were investigated.Moreover,temperature,host rock,

  12. Targeting glucose metabolism in cancer: new class of agents for loco-regional and systemic therapy of liver cancer and beyond?

    Science.gov (United States)

    Savic, Lynn Jeanette; Chapiro, Julius; Duwe, Gregor; Geschwind, Jean-François

    2016-01-01

    Hepatocellular carcinoma (HCC) is one of the most prevalent cancers and the third leading cause of cancer-related deaths worldwide. In patients with unresectable disease, loco-regional catheter-based intra-arterial therapies (IAT) can achieve selective tumor control while minimizing systemic toxicity. As molecular features of tumor growth and microenvironment are better understood, new targets arise for selective anticancer therapy. Particularly, antiglycolytic drugs that exploit the hyperglycolytic cancer cell metabolism – also known as the ‘Warburg effect’ – have emerged as promising therapeutic options. Thus, future developments will combine the selective character of loco-regional drug delivery platforms with highly specific molecular targeted antiglycolytic agents. This review will exemplify literature on antiglycolytic approaches and particularly focus on intra-arterial delivery methods. PMID:26989470

  13. Targeting glucose metabolism in cancer: new class of agents for loco-regional and systemic therapy of liver cancer and beyond?

    Science.gov (United States)

    Savic, Lynn Jeanette; Chapiro, Julius; Duwe, Gregor; Geschwind, Jean-François

    2016-01-01

    Hepatocellular carcinoma (HCC) is one of the most prevalent cancers and the third leading cause of cancer-related deaths worldwide. In patients with unresectable disease, loco-regional catheter-based intra-arterial therapies (IAT) can achieve selective tumor control while minimizing systemic toxicity. As molecular features of tumor growth and microenvironment are better understood, new targets arise for selective anticancer therapy. Particularly, antiglycolytic drugs that exploit the hyperglycolytic cancer cell metabolism - also known as the 'Warburg effect' - have emerged as promising therapeutic options. Thus, future developments will combine the selective character of loco-regional drug delivery platforms with highly specific molecular targeted antiglycolytic agents. This review will exemplify literature on antiglycolytic approaches and particularly focus on intra-arterial delivery methods.

  14. Identifying appropriate spatial scales for marine conservation and management using a larval dispersal model: The case of Concholepas concholepas (loco) in Chile

    Science.gov (United States)

    Garavelli, Lysel; Kaplan, David Michael; Colas, François; Stotz, Wolfgang; Yannicelli, Beatriz; Lett, Christophe

    2014-05-01

    Along the coast of Chile, fisheries targeting the marine gastropod Concholepas concholepas, commonly named “loco”, were highly valuable until the end of the 80s when catches declined significantly. Since the late 90s, a management plan based on territorial-user-rights areas has been implemented, with limited effect on stock recovery. More effective loco conservation and management is impeded by lack of information regarding connectivity via larval dispersal between these individually-managed areas. To develop a regional view of loco connectivity, we integrate loco life history information into a biophysical, individual-based larval dispersal model. This model is used to evaluate scales of loco connectivity and seasonality in connectivity patterns, as well as to partition the coast into largely disconnected subpopulations using a recently developed connectivity-matrix clustering algorithm. We find mean dispersal distances ranging from 170 to 220 km depending on release depth of larvae and planktonic larval duration. Settlement success levels depend quantitatively on the physical and biological processes included in the model, but connectivity patterns remain qualitatively similar. Model estimates of settlement success peak for larval release dates in late austral autumn, consistent with field results and with favorable conditions for larval coastal retention due to weak upwelling during austral autumn. Despite the relatively homogeneous Chilean coastline, distinct subpopulations with minimal connectivity between them are readily identifiable. Barriers to connectivity that are robust to changes in model configuration exist at 23°S and 29°S latitudes. These zones are all associated with important headlands and embayments of the Chilean coast.

  15. Towards a framework for teaching about information technology risk in health care: Simulating threats to health data and patient safety

    Directory of Open Access Journals (Sweden)

    Elizabeth M. Borycki

    2015-09-01

    Full Text Available In this paper the author describes work towards developing an integrative framework for educating health information technology professionals about technology risk. The framework considers multiple sources of risk to health data quality and integrity that can result from the use of health information technology (HIT and can be used to teach health professional students about these risks when using health technologies. This framework encompasses issues and problems that may arise from varied sources, including intentional alterations (e.g. resulting from hacking and security breaches as well as unintentional breaches and corruption of data (e.g. resulting from technical problems, or from technology-induced errors. The framework that is described has several levels: the level of human factors and usability of HIT, the level of monitoring of security and accuracy, the HIT architectural level, the level of operational and physical checks, the level of healthcare quality assurance policies and the data risk management strategies level. Approaches to monitoring and simulation of risk are also discussed, including a discussion of an innovative approach to monitoring potential quality issues. This is followed by a discussion of the application (using computer simulations to educate both students and health information technology professionals about the impact and spread of technology-induced and related types of data errors involving HIT.

  16. Simulations

    CERN Document Server

    Ngada, N M

    2015-01-01

    The complexity and cost of building and running high-power electrical systems make the use of simulations unavoidable. The simulations available today provide great understanding about how systems really operate. This paper helps the reader to gain an insight into simulation in the field of power converters for particle accelerators. Starting with the definition and basic principles of simulation, two simulation types, as well as their leading tools, are presented: analog and numerical simulations. Some practical applications of each simulation type are also considered. The final conclusion then summarizes the main important items to keep in mind before opting for a simulation tool or before performing a simulation.

  17. MiR-422a promotes loco-regional recurrence by targeting NT5E/CD73 in head and neck squamous cell carcinoma.

    Science.gov (United States)

    Bonnin, Nathalie; Armandy, Emma; Carras, Julien; Ferrandon, Sylvain; Battiston-Montagne, Priscillia; Aubry, Marc; Guihard, Sébastien; Meyronet, David; Foy, Jean-Philippe; Saintigny, Pierre; Ledrappier, Sonia; Jung, Alain; Rimokh, Ruth; Rodriguez-Lafrasse, Claire; Poncet, Delphine

    2016-07-12

    At the time of diagnosis, 60% of patients with head and neck squamous cell carcinoma (HNSCC) present tumors in an advanced stage (III-IV) of disease and 80% will relapse within the first two years post-treatment, due to their frequent radio(chemo)resistance. To identify new molecular targets and companion biomarkers, we have investigated the miRNome of 75 stage III-IV oropharynx tumors without relapse (R) or with loco-regional relapse (non-responder, NR) within two years post-treatment. Interestingly, miR-422a was significantly downregulated in NR tumors, in agreement with the increase in cell proliferation and adhesion induced by miR-422a inhibition in vitro. Furthermore, we identified CD73/NT5E oncogene as target of miR-422a. Indeed, modulation of the endogenous level of miR-422a inversely influences the expression and the enzymatic activity of CD73. Moreover, knocking down CD73 mimics the effects of miR-422a upregulation. Importantly, in tumors, miR-422a and CD73 expression levels are inversely correlated, and both are predictive of relapse free survival - especially considering loco(regional) recurrence - in vitro two independent cohorts of advanced oropharynx or HNSCC (N=255) tumors. In all, we reported, for the first time, that MiR-422a and its target CD73 are involved in early loco(regional) recurrence of HNSCC tumors and are new targets for personalized medicine.

  18. From Usability Testing to Clinical Simulations: Bringing Context into the Design and Evaluation of Usable and Safe Health Information Technologies

    DEFF Research Database (Denmark)

    Kushniruk, Andre; Nøhr, Christian; Jensen, Sanne

    2013-01-01

    Objectives: The objective of this paper is to explore human factors approaches to understanding the use of health information technology (HIT) by extending usability engineering approaches to include analysis of the impact of clinical context through use of clinical simulations. Methods: Methods...

  19. Loco-regional control after neo-adjuvant chemotherapy and conservative treatment for locally advanced breast cancer patients.

    Science.gov (United States)

    Levy, Antonin; Borget, Isabelle; Bahri, Manel; Arnedos, Monica; Rivin, Eleonor; Vielh, Philippe; Balleyguier, Corinne; Rimareix, Françoise; Bourgier, Céline

    2014-01-01

    Breast-conserving treatment (BCT) has been validated for breast cancer patients receiving adjuvant chemotherapy. Our objective was to evaluate the difference in loco-regional recurrence (LRR) rates between BCT and mastectomy in patients receiving radiation therapy after neo-adjuvant chemotherapy (NCT). A retrospective data base was used to identify all patients with breast cancer undergoing NCT from 2002 to 2007. Patients with initial metastatic disease were excluded from this analysis. LRR was compared between those undergoing BCT and mastectomy. Individual variables associated with LRR were evaluated. Two hundred eighty-four patients were included, 111 (39%) underwent BCT and 173 (61%) mastectomy. Almost all patients (99%) in both groups received postoperative radiation. Pathologic complete response was seen in 37 patients, of which 28 underwent BCT (p loco-regional control rate was 91% (95% CI: 86-94%). The 10-year LRR rate was similar in the BCT group (9.2% [95% CI: 4.9-16.7%]) and in the mastectomy group (10.7% [95% CI: 5.9-15.2%]; p = 0.8). Ten-year overall survival (OS) rates (63% [95% CI: 46-79%] in the BCT group; 60% [95% CI: 47-73%] in the mastectomy group, p = 0.8) were not statistically different between the two patient populations. Multivariate analysis showed that AJCC stage ≥ III (HR: 2.6; 95% CI: 1.2-5.8; p = 0.02), negative PR (HR: 6; 95% CI: 1.2-30.6, p = 0.03), and number of positive lymph nodes ≥3 (HR: 2.5; 95% CI: 1.1-5.9; p = 0.03) were independent predictors of LRR. Ten-year OS was similar in the BCT and in the mastectomy group (p = 0.1). The rate of LRR was low and did not significantly differ between the BCT and the mastectomy group after NCT. Randomized trials assessing whether mastectomy can be safely omitted in selected breast cancer patients (nonstage III tumors or those which do not require adjuvant hormone suppression) which respond to NCT are required.

  20. Development of Virtual Airspace Simulation Technology - Real-Time (VAST-RT) Capability 2 and Experimental Plans

    Science.gov (United States)

    Lehmer, R.; Ingram, C.; Jovic, S.; Alderete, J.; Brown, D.; Carpenter, D.; LaForce, S.; Panda, R.; Walker, J.; Chaplin, P.; hide

    2006-01-01

    The Virtual Airspace Simulation Technology - Real-Time (VAST-RT) Project, an element cf NASA's Virtual Airspace Modeling and Simulation (VAMS) Project, has been developing a distributed simulation capability that supports an extensible and expandable real-time, human-in-the-loop airspace simulation environment. The VAST-RT system architecture is based on DoD High Level Architecture (HLA) and the VAST-RT HLA Toolbox, a common interface implementation that incorporates a number of novel design features. The scope of the initial VAST-RT integration activity (Capability 1) included the high-fidelity human-in-the-loop simulation facilities located at NASA/Ames Research Center and medium fidelity pseudo-piloted target generators, such as the Airspace Traffic Generator (ATG) being developed as part of VAST-RT, as well as other real-time tools. This capability has been demonstrated in a gate-to-gate simulation. VAST-RT's (Capability 2A) has been recently completed, and this paper will discuss the improved integration of the real-time assets into VAST-RT, including the development of tools to integrate data collected across the simulation environment into a single data set for the researcher. Current plans for the completion of the VAST-RT distributed simulation environment (Capability 2B) and its use to evaluate future airspace capacity enhancing concepts being developed by VAMS will be discussed. Additionally, the simulation environment's application to other airspace and airport research projects is addressed.

  1. New tools and technology for the study of human performance in simulator experiments

    Energy Technology Data Exchange (ETDEWEB)

    Droeivoldsmo, Asgeir

    2003-07-01

    This thesis suggests that new tools and technology can be used for production of relevant data and insights from the study of human performance in simulator and field experiments. It examines some of the theoretical perspectives behind data collection and human performance assessment, and argues for a high resemblance of the real world and use of subject matter expertise in simulator studies. A model is proposed, suggesting that human performance measurement should be tightly coupled to the topic of study and have a close connection to the time line. This coupling requires new techniques for continuous data collection, and eye movement tracking has been identified as a promising basis for this type of measures. One way of improving realism is to create virtual environments allowing for controlling more of the environment surrounding the test subjects. New application areas for virtual environments are discussed for use in control room and field studies. The combination of wearable computing, virtual and augmented (the use of computers to overlay virtual information onto the real world) reality provides many new possibilities to present information to operators. In two experiments, virtual and augmented reality techniques were used to visualise radiation fields for operators in a contaminated nuclear environment. This way the operators could train for and execute their tasks in a way that minimised radiation exposure to the individual operator. Both experiments were successful in proving the concept of radiation visualisation. Virtual environments allow for early end-user feedback in the design and refurbishment of control room man-machine interfaces. The practical usability of VR in the control room setting was tested in two control room design experiments. The results show that with the right tools for solving the tasks under test, even desktop presentations of the virtual environment can provide sufficient resemblance of the real world. Computerised data

  2. The Terascale Simulation Tools and Technologies Center Annual Report August 15, 2001-September 30, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Glimm, J; Brown, D L; Freitag, L

    2002-09-30

    The overall goal of the TSTT Center is to enable the scientific community to more easily use modern high-order, adaptive, parallel mesh and discretization tools. To achieve this goal, we are following three distinct but related paths. The first is to work directly with a number of lead application teams (for the most part SciDAC-funded) to use such technologies in their application domains. The second is to create new technology that eases the use of such tools, not only for our designated application partners, but across a broad range of application areas that require mesh and discretization tools for scientific simulation. The main technology thrust is not to create new tools (although some of this will occur), but to create new capabilities that will allow the use of these tools interoperably. This very profound step can be compared to the shift from hand craftmanship to manufactured products with interchangable components which revolutionized the world economy one to two centuries ago. The third component of our efforts is to embed this work in a larger framework of related activities, each seeking a similar, and profound, change in the practice of computational science. To ensure the relevance of our work to the SciDAC program goals, we originally selected six application areas, and in each, one or more application projects and teams with which to work directly. One application collaboration which targeted the development of an adaptive mesh refinement capability for the oceanographic code POP was postponed and may be dropped due to unanticipated technical obstacles in the specific goal selected. One new application involving jet breakup for spray combustion was added. The initial job of establishing good working relations, agreement on a plan of action, and obtaining initial results was accomplished in all cases. In general, our work with the applications has been more difficult than anticipated, in spite of the experience of the TSTT team members in similar

  3. The Terascale Simulation Tools and Technologies Center Annual Report August 15, 2001-September 30, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Glimm, J; Brown, D L; Freitag, L

    2002-09-30

    The overall goal of the TSTT Center is to enable the scientific community to more easily use modern high-order, adaptive, parallel mesh and discretization tools. To achieve this goal, we are following three distinct but related paths. The first is to work directly with a number of lead application teams (for the most part SciDAC-funded) to use such technologies in their application domains. The second is to create new technology that eases the use of such tools, not only for our designated application partners, but across a broad range of application areas that require mesh and discretization tools for scientific simulation. The main technology thrust is not to create new tools (although some of this will occur), but to create new capabilities that will allow the use of these tools interoperably. This very profound step can be compared to the shift from hand craftmanship to manufactured products with interchangable components which revolutionized the world economy one to two centuries ago. The third component of our efforts is to embed this work in a larger framework of related activities, each seeking a similar, and profound, change in the practice of computational science. To ensure the relevance of our work to the SciDAC program goals, we originally selected six application areas, and in each, one or more application projects and teams with which to work directly. One application collaboration which targeted the development of an adaptive mesh refinement capability for the oceanographic code POP was postponed and may be dropped due to unanticipated technical obstacles in the specific goal selected. One new application involving jet breakup for spray combustion was added. The initial job of establishing good working relations, agreement on a plan of action, and obtaining initial results was accomplished in all cases. In general, our work with the applications has been more difficult than anticipated, in spite of the experience of the TSTT team members in similar

  4. Feasibility Study of Cryogenic Cutting Technology by Using a Computer Simulation and Manufacture of Main Components for Cryogenic Cutting System

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Kyun; Lee, Dong Gyu; Lee, Kune Woo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Song, Oh Seop [Chungnam National University, Deajeon (Korea, Republic of)

    2009-06-15

    Cryogenic cutting technology is one of the most suitable technologies for dismantling nuclear facilities due to the fact that a secondary waste is not generated during the cutting process. In this paper, the feasibility of cryogenic cutting technology was investigated by using a computer simulation. In the computer simulation, a hybrid method combined with the SPH (smoothed particle hydrodynamics) method and the FE (finite element) method was used. And also, a penetration depth equation, for the design of the cryogenic cutting system, was used and the design variables and operation conditions to cut a 10 mm thickness for steel were determined. Finally, the main components of the cryogenic cutting system were manufactures on the basis of the obtained design variables and operation conditions.

  5. Modeling and simulation of ocean mining subsystem based on virtual prototyping technology

    Institute of Scientific and Technical Information of China (English)

    XIA Yi-min; BU Ying-yong; MA Zhi-guo; ZAO Hai-ming; LUO Bo-wen

    2005-01-01

    According to the virtual prototyping technology and the theory of dynamics of multi-rigid-body system, a virtual prototyping of ocean mining vehicle was constructed by using 3-dimensional entity modeling software (Pro/E), automatic dynamic analysis of mechanical systems(ADAMS) and advanced visual software(AVS). After 32 new modules were developed with C++ at AVS platform, the interface problems of the 3 types of software were solved effectively and a visual environment for ocean mining subsystem was constructed. Based on the similarity theory and similarity experiments, the validity and reliability of the virtual prototyping were verified. By using the constructed virtual prototyping, the relevant parameters, such as cutting depth, rotation speed of roller,marching speed of mining vehicle can be adjusted one by one. After repeatable virtual tests and analysis its corresponding dynamic characteristics, the structure parameter of mining vehicle and the parameter of mining process can be optimized fast and accurately. The experiment and simulation results show that, under the controlled mining parameters, 4 function expressions between the average force of single pick,average torque,average cutting power,energy consumption ratio and cutting depth are obtained. The maximum force of a single pick is less than 11 090 N and the maximum torque of the roller is less than 3600N·m.

  6. Discrete Event Simulation-Based Resource Modelling in Health Technology Assessment.

    Science.gov (United States)

    Salleh, Syed; Thokala, Praveen; Brennan, Alan; Hughes, Ruby; Dixon, Simon

    2017-07-03

    The objective of this article was to conduct a systematic review of published research on the use of discrete event simulation (DES) for resource modelling (RM) in health technology assessment (HTA). RM is broadly defined as incorporating and measuring effects of constraints on physical resources (e.g. beds, doctors, nurses) in HTA models. Systematic literature searches were conducted in academic databases (JSTOR, SAGE, SPRINGER, SCOPUS, IEEE, Science Direct, PubMed, EMBASE) and grey literature (Google Scholar, NHS journal library), enhanced by manual searchers (i.e. reference list checking, citation searching and hand-searching techniques). The search strategy yielded 4117 potentially relevant citations. Following the screening and manual searches, ten articles were included. Reviewing these articles provided insights into the applications of RM: firstly, different types of economic analyses, model settings, RM and cost-effectiveness analysis (CEA) outcomes were identified. Secondly, variation in the characteristics of the constraints such as types and nature of constraints and sources of data for the constraints were identified. Thirdly, it was found that including the effects of constraints caused the CEA results to change in these articles. The review found that DES proved to be an effective technique for RM but there were only a small number of studies applied in HTA. However, these studies showed the important consequences of modelling physical constraints and point to the need for a framework to be developed to guide future applications of this approach.

  7. Automatic classification and defect verification based on inspection technology with lithography simulation

    Science.gov (United States)

    Kato, Masaya; Inuzuka, Hideki; Kosuge, Takeshi; Yoshikawa, Shingo; Kanno, Kayoko; Imai, Hidemichi; Miyashita, Hiroyuki; Vacca, Anthony; Fiekowsky, Peter; Fiekowsky, Dan

    2015-10-01

    Even small defects on the main patterns can create killer defects on the wafer, whereas the same defect on or near the decorative patterns may be completely benign to the wafer functionality. This ambiguity often causes operators and engineers to put a mask "on hold" to be analyzed by an AIMS™ tool which slows the manufacturing time and increases mask cost. In order to streamline the process, mask shops need a reliable way to quickly identify the wafer impact of defects during mask inspection review reducing the number of defects requiring AIMS™ analysis. Source Mask Optimization (SMO) techniques are now common on sub 20nm node critical reticle patterns These techniques create complex reticle patterns which often makes it difficult for inspection tool operators to identify the desired wafer pattern from the surrounding nonprinting patterns in advanced masks such as SMO, Inverse Lithography Technology (ILT), Negative Tone Development (NTD). In this study, we have tested a system that generates aerial simulation images directly from the inspection tool images. The resulting defect dispositions from a program defect test mask along with numerous production mask defects have been compared to the dispositions attained from AIMS™ analysis. The results of our comparisons are presented, as well as the impact to mask shop productivity.

  8. System Dynamics Simulation Modelling of the Impact of Technology Capital on Economic Growth of the Republic of Croatia

    Directory of Open Access Journals (Sweden)

    Ivona Milić Beran

    2013-07-01

    Full Text Available The development of science and technology plays a major role in economic growth. In some developed countries, the impact of technological advancement has reached 60-70% relative to other factors. Technology has become the main force in economic growth. Science and technology, theory and practice have become increasingly linked forming a single chain, promoting further development of technology, thus creating a need for continuous innovation and invention activities. Globalization, in particular the globalization of the economy, is a direct result of the scientific and technological revolution which creates links and scope for further development of the productive forces. The underlying driving force of globalization is technological development which makes the world a smaller place, both in terms of space and time, bringing qualitative and quantitative changes to the economic, political and cultural fields. System dynamics simulation modelling is one of the most suitable and effective scientific methods for modelling the dynamics of complex, non-linear natural, economic and technical systems. It enables monitoring and assessment of the impact of technology capital on economic growth. In creating a system dynamics simulation model of the impact of technology capital on economic growth of the Republic of Croatia we have created a structure diagram, mental-verbal model and mathematical model for the period between 1999 and 2009. Since system dynamics simulation model provides answers to the “what if” questions, two scenarios were constructed to analyse the economic growth influenced by technology capital change. The first scenario gives an answer to the question what would have happened to the economic growth of Croatia in the relevant period had there been a steady increase in investment in research and development, the implementation of advanced technology and investment in general. The second scenario gives an answer to the question what

  9. Exploring Mechanisms for Effective Technology-Enhanced Simulation-based Education in Wilderness Medicine: A Systematic Review.

    Science.gov (United States)

    MacKinnon, Ralph; Aitken, Deborah; Humphries, Christopher

    2015-12-17

     Technology-enhanced simulation is well-established in healthcare teaching curricula, including those regarding wilderness medicine. Compellingly, the evidence base for the value of this educational modality to improve learner competencies and patient outcomes are increasing.  The aim was to systematically review the characteristics of technology-enhanced simulation presented in the wilderness medicine literature to date. Then, the secondary aim was to explore how this technology has been used and if the use of this technology has been associated with improved learner or patient outcomes.  EMBASE and MEDLINE were systematically searched from 1946 to 2014, for articles on the provision of technology-enhanced simulation to teach wilderness medicine. Working independently, the team evaluated the information on the criteria of learners, setting, instructional design, content, and outcomes.  From a pool of 37 articles, 11 publications were eligible for systematic review. The majority of learners in the included publications were medical students, settings included both indoors and outdoors, and the main focus clinical content was initial trauma management with some including leadership skills. The most prevalent instructional design components were clinical variation and cognitive interactivity, with learner satisfaction as the main outcome.  The results confirm that the current provision of wilderness medicine utilizing technology-enhanced simulation is aligned with instructional design characteristics that have been used to achieve effective learning. Future research should aim to demonstrate the translation of learning into the clinical field to produce improved learner outcomes and create improved patient outcomes.

  10. High-fidelity simulator technology may not be superior to traditional low-fidelity equipment for neonatal resuscitation training.

    Science.gov (United States)

    Finan, E; Bismilla, Z; Whyte, H E; Leblanc, V; McNamara, P J

    2012-04-01

    Despite completing accredited resuscitation training, neonatal trainees often feel unprepared to deal with real-life clinical emergencies. High-fidelity simulator (HFS) technology offers the potential of recreating a realistic stressful clinical environment to aid training and evaluation. To date, there are limited data examining the physiological impact of this training modality in comparison to less costly alternatives. The objective of this study was to compare the effects of low-fidelity simulator (LFS) versus HFS technology on performance levels, objective and subjective measures of stress in neonatal trainees. Sixteen neonatal fellows were invited to participate in a prospective randomized study. Subjects were divided into pairs and randomized to LFS or HFS for completion of scenario I. After an interval of 1 month, fellow teams crossed over to complete scenario II using the alternative simulator technology. Technical and non-technical skills were assessed using validated resuscitation scoring tools. Participants recorded subjective stress at sequential time points before and after each simulation. Buccal cortisol was measured at each corresponding time point and comparison between HFS and LFS groups was made. The mean overall resuscitation performance score was 75.8%±10, but there was no difference in performance between HFS and LFS groups. There was also no significant difference in non-technical skills performance between groups. Salivary cortisol increased over the duration of the simulated experience, but there were no differences between the two groups (P=0.001, two-way repeated measures analysis of variance). We also identified changes in subjective measures of stress (P<0.001, analysis of variance) over time, but again there were no differences between groups. Simulated neonatal resuscitations induce a significant stress response in neonatal trainees; however, we were unable to identify any difference in stress measures between HFS and LFS. These

  11. An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs.

    Science.gov (United States)

    Pan, Zhu; Zhu, Jinwei; Shang, Yuan; Wei, Zhiyi; Jia, Min; Xia, Caihao; Wen, Wenyu; Wang, Wenning; Zhang, Mingjie

    2013-06-01

    LGN plays essential roles in asymmetric cell divisions via its N-terminal TPR-motif-mediated binding to mInsc and NuMA. This scaffolding activity requires the release of the autoinhibited conformation of LGN by binding of Gα(i) to its C-terminal GoLoco (GL) motifs. The interaction between the GL and TPR motifs of LGN represents a distinct GL/target binding mode with an unknown mechanism. Here, we show that two consecutive GL motifs of LGN form a minimal TPR-motif-binding unit. GL12 and GL34 bind to TPR0-3 and TPR4-7, respectively. The crystal structure of a truncated LGN reveals that GL34 forms a pair of parallel α helices and binds to the concave surface of TPR4-7, thereby preventing LGN from binding to other targets. Importantly, the GLs bind to TPR motifs with a mode distinct from that observed in the GL/Gα(i)·GDP complexes. Our results also indicate that multiple and orphan GL motif proteins likely respond to G proteins with distinct mechanisms.

  12. Influence of back-gate stress on the back-gate threshold voltage of a LOCOS-isolated SOI MOSFET

    Institute of Scientific and Technical Information of China (English)

    梅博; 毕津顺; 李多力; 刘思南; 韩郑生

    2012-01-01

    The performance of a LOCOS-isolated SOI MOSFET heavily depends on its back-gate characteristic, which can be affected by back-gate stress,A large voltage stress was applied to the back gate of SOI devices for at least 30 s at room temperature,which could effectively modify the back-gate threshold voltage of these devices.This modification is stable and time invariant.In order to improve the back-gate threshold voltage,positive substrate bias was applied to NMOS devices and negative substrate bias was applied to PMOS devices,These results suggest that there is a leakage path between source and drain along the silicon island edge,and the application of large backgate bias with the source,drain and gate grounded can strongly affect this leakage path.So we draw the conclusion that the back-gate threshold voltage,which is directly related to the leakage current,can be influenced by back-gate stress.

  13. Local coupling (LoCo) vs. large-scale coupled (LsCo) land-atmosphere interactions in idealized experiments

    Science.gov (United States)

    Gentine, P.; Lintner, B. R.; Findell, K. L.; Rochetin, N.; Sobel, A. H.; Anber, U. M.

    2014-12-01

    We will present two idealized epxeriments/methodologies to investigate local (LoCo) and large-scale (LsCo) coupling between the surface and the atmsophere: the contiental Radiative-Convective Equilibrium (RCE) and the continental Weak Temperature Gradient (WTG). The RCE defines an equilibrium state of coupling between the surafce and the atmosphere isolated from any large-scale dependence, which were investigated within the single column model of the Laboratoire de Meteorologie Dynamique (LMD) coupled to a simple bucket land model. This studies emphasizes the role of low-level cloud and the diurnal cylce of the boundary layer on the final state of the system. In the WTG we investigate the coupling between the surface and the atmosphere during the dry and wet season of the Amazon with the WRF model coupled to the NOAH land-surface model. Large-scale coupling is obtained with the WTG. The dry and wet season demonstrate very fundamental behavior: in the dry season deep convection is generated by radiative cooling in the higher troposhere and is disconnected from the surface. In the wet season the coupling between the surface and the atmosphere is much tighter. We suggest that the WTG is a powerful tool to investigate the coupling between the surface and the atmosphere, which solves two major issues: the limited resolution of convection in GCMs and the lack of large-scale coupling in CRM. Later investigation will look at the effect of deforestation, water table and distance from the ocean.

  14. NETL to establish Dynamic Simulation Research and Training Center to promote IGCC technology with CO2 cpture

    Energy Technology Data Exchange (ETDEWEB)

    Provost, G.; Zitney, S.; Turton, R.; Erbes, M.; Stone, H.; Bhattacharyya, D.; Liese, E.; McClintock, M.; Quintrell, M.

    2009-01-01

    To meet increasing demand for education and experience with commercial-scale, coal-fired, integrated gasification combined cycle (IGCC) plants with CO2 capture, the Department of Energy’s (DOE) National Energy Technology Laboratory (NETL) is leading a project to deploy a generic, full-scope, real-time IGCC dynamic plant simulator for use in establishing a world-class research and training center, and to promote and demonstrate IGCC technology to power industry personnel. The simulator, being built by Invensys Process Systems (IPS), will be installed at two separate sites, at NETL and West Virginia University (WVU), and will combine a process/gasification simulator with a power/combined-cycle simulator together in a single dynamic simulation framework for use in engineering research studies and training applications. The simulator, scheduled to be launched in mid-year 2010, will have the following capabilities: High-fidelity, dynamic model of process-side (gasification and gas cleaning with CO2 capture) and power-block-side (combined cycle) for a generic IGCC plant fueled by coal and/or petroleum coke. Highly flexible configuration that allows concurrent training on separate gasification and combined cycle simulators, or up to two IGCC simulators. Ability to enhance and modify the plant model to facilitate studies of changes in plant configuration, equipment, and control strategies to support future R&D efforts. Training capabilities including startup, shutdown, load following and shedding, response to fuel and ambient condition variations, control strategy analysis (turbine vs. gasifier lead, etc.), representative malfunctions/trips, alarms, scenarios, trending, snapshots, data historian, etc. To support this effort, process descriptions and control strategies were developed for key sections of the plant as part of the detailed functional specification, which is serving as the basis of the simulator development. In this paper, we highlight the contents of the

  15. Quantitative risk assessment integrated with process simulator for a new technology of methanol production plant using recycled CO₂.

    Science.gov (United States)

    Di Domenico, Julia; Vaz, Carlos André; de Souza, Maurício Bezerra

    2014-06-15

    The use of process simulators can contribute with quantitative risk assessment (QRA) by minimizing expert time and large volume of data, being mandatory in the case of a future plant. This work illustrates the advantages of this association by integrating UNISIM DESIGN simulation and QRA to investigate the acceptability of a new technology of a Methanol Production Plant in a region. The simulated process was based on the hydrogenation of chemically sequestered carbon dioxide, demanding stringent operational conditions (high pressures and temperatures) and involving the production of hazardous materials. The estimation of the consequences was performed using the PHAST software, version 6.51. QRA results were expressed in terms of individual and social risks. Compared to existing tolerance levels, the risks were considered tolerable in nominal conditions of operation of the plant. The use of the simulator in association with the QRA also allowed testing the risk in new operating conditions in order to delimit safe regions for the plant.

  16. Monte Carlo simulation of a compact microbeam radiotherapy system based on carbon nanotube field emission technology.

    Science.gov (United States)

    Schreiber, Eric C; Chang, Sha X

    2012-08-01

    Microbeam radiation therapy (MRT) is an experimental radiotherapy technique that has shown potent antitumor effects with minimal damage to normal tissue in animal studies. This unique form of radiation is currently only produced in a few large synchrotron accelerator research facilities in the world. To promote widespread translational research on this promising treatment technology we have proposed and are in the initial development stages of a compact MRT system that is based on carbon nanotube field emission x-ray technology. We report on a Monte Carlo based feasibility study of the compact MRT system design. Monte Carlo calculations were performed using EGSnrc-based codes. The proposed small animal research MRT device design includes carbon nanotube cathodes shaped to match the corresponding MRT collimator apertures, a common reflection anode with filter, and a MRT collimator. Each collimator aperture is sized to deliver a beam width ranging from 30 to 200 μm at 18.6 cm source-to-axis distance. Design parameters studied with Monte Carlo include electron energy, cathode design, anode angle, filtration, and collimator design. Calculations were performed for single and multibeam configurations. Increasing the energy from 100 kVp to 160 kVp increased the photon fluence through the collimator by a factor of 1.7. Both energies produced a largely uniform fluence along the long dimension of the microbeam, with 5% decreases in intensity near the edges. The isocentric dose rate for 160 kVp was calculated to be 700 Gy∕min∕A in the center of a 3 cm diameter target. Scatter contributions resulting from collimator size were found to produce only small (<7%) changes in the dose rate for field widths greater than 50 μm. Dose vs depth was weakly dependent on filtration material. The peak-to-valley ratio varied from 10 to 100 as the separation between adjacent microbeams varies from 150 to 1000 μm. Monte Carlo simulations demonstrate that the proposed compact MRT system

  17. Structured grid technology to enable flow simulation in an integrated system environment

    Science.gov (United States)

    Remotigue, Michael Gerard

    An application-driven Computational Fluid Dynamics (CFD) environment needs flexible and general tools to effectively solve complex problems in a timely manner. In addition, reusable, portable, and maintainable specialized libraries will aid in rapidly developing integrated systems or procedures. The presented structured grid technology enables the flow simulation for complex geometries by addressing grid generation, grid decomposition/solver setup, solution, and interpretation. Grid generation is accomplished with the graphical, arbitrarily-connected, multi-block structured grid generation software system (GUM-B) developed and presented here. GUM-B is an integrated system comprised of specialized libraries for the graphical user interface and graphical display coupled with a solid-modeling data structure that utilizes a structured grid generation library and a geometric library based on Non-Uniform Rational B-Splines (NURBS). A presented modification of the solid-modeling data structure provides the capability for arbitrarily-connected regions between the grid blocks. The presented grid generation library provides algorithms that are reliable and accurate. GUM-B has been utilized to generate numerous structured grids for complex geometries in hydrodynamics, propulsors, and aerodynamics. The versatility of the libraries that compose GUM-B is also displayed in a prototype to automatically regenerate a grid for a free-surface solution. Grid decomposition and solver setup is accomplished with the graphical grid manipulation and repartition software system (GUMBO) developed and presented here. GUMBO is an integrated system comprised of specialized libraries for the graphical user interface and graphical display coupled with a structured grid-tools library. The described functions within the grid-tools library reduce the possibility of human error during decomposition and setup for the numerical solver by accounting for boundary conditions and connectivity. GUMBO is

  18. Advancing adaptive optics technology: Laboratory turbulence simulation and optimization of laser guide stars

    Science.gov (United States)

    Rampy, Rachel A.

    Since Galileo's first telescope some 400 years ago, astronomers have been building ever-larger instruments. Yet only within the last two decades has it become possible to realize the potential angular resolutions of large ground-based telescopes, by using adaptive optics (AO) technology to counter the blurring effects of Earth's atmosphere. And only within the past decade have the development of laser guide stars (LGS) extended AO capabilities to observe science targets nearly anywhere in the sky. Improving turbulence simulation strategies and LGS are the two main topics of my research. In the first part of this thesis, I report on the development of a technique for manufacturing phase plates for simulating atmospheric turbulence in the laboratory. The process involves strategic application of clear acrylic paint onto a transparent substrate. Results of interferometric characterization of the plates are described and compared to Kolmogorov statistics. The range of r0 (Fried's parameter) achieved thus far is 0.2--1.2 mm at 650 nm measurement wavelength, with a Kolmogorov power law. These plates proved valuable at the Laboratory for Adaptive Optics at University of California, Santa Cruz, where they have been used in the Multi-Conjugate Adaptive Optics testbed, during integration and testing of the Gemini Planet Imager, and as part of the calibration system of the on-sky AO testbed named ViLLaGEs (Visible Light Laser Guidestar Experiments). I present a comparison of measurements taken by ViLLaGEs of the power spectrum of a plate and the real sky turbulence. The plate is demonstrated to follow Kolmogorov theory well, while the sky power spectrum does so in a third of the data. This method of fabricating phase plates has been established as an effective and low-cost means of creating simulated turbulence. Due to the demand for such devices, they are now being distributed to other members of the AO community. The second topic of this thesis pertains to understanding and

  19. Assessment of Vehicle Sizing, Energy Consumption and Cost Through Large Scale Simulation of Advanced Vehicle Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Moawad, Ayman [Argonne National Lab. (ANL), Argonne, IL (United States); Kim, Namdoo [Argonne National Lab. (ANL), Argonne, IL (United States); Shidore, Neeraj [Argonne National Lab. (ANL), Argonne, IL (United States); Rousseau, Aymeric [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-01-01

    The U.S. Department of Energy (DOE) Vehicle Technologies Office (VTO) has been developing more energy-efficient and environmentally friendly highway transportation technologies that will enable America to use less petroleum. The long-term aim is to develop "leapfrog" technologies that will provide Americans with greater freedom of mobility and energy security, while lowering costs and reducing impacts on the environment. This report reviews the results of the DOE VTO. It gives an assessment of the fuel and light-duty vehicle technologies that are most likely to be established, developed, and eventually commercialized during the next 30 years (up to 2045). Because of the rapid evolution of component technologies, this study is performed every two years to continuously update the results based on the latest state-of-the-art technologies.

  20. The Dynamics of Son Preference, Technology Diffusion, and Fertility Decline Underlying Distorted Sex Ratios at Birth: A Simulation Approach.

    Science.gov (United States)

    Kashyap, Ridhi; Villavicencio, Francisco

    2016-10-01

    We present a micro-founded simulation model that formalizes the "ready, willing, and able" framework, originally used to explain historical fertility decline, to the practice of prenatal sex selection. The model generates sex ratio at birth (SRB) distortions from the bottom up and attempts to quantify plausible levels, trends, and interactions of son preference, technology diffusion, and fertility decline that underpin SRB trajectories at the macro level. Calibrating our model for South Korea, we show how even as the proportion with a preference for sons was declining, SRB distortions emerged due to rapid diffusion of prenatal sex determination technology combined with small but growing propensities to abort at low birth parities. Simulations reveal that relatively low levels of son preference (about 20 % to 30 % wanting one son) can result in skewed SRB levels if technology diffuses early and steadily, and if fertility falls rapidly to encourage sex-selective abortion at low parities. Model sensitivity analysis highlights how the shape of sex ratio trajectories is particularly sensitive to the timing and speed of prenatal sex-determination technology diffusion. The maximum SRB levels reached in a population are influenced by how the readiness to abort rises as a function of the fertility decline.

  1. Towards personalised management of atherosclerosis via computational models in vascular clinics: technology based on patient-specific simulation approach.

    Science.gov (United States)

    Díaz-Zuccarini, Vanessa; Di Tomaso, Giulia; Agu, Obiekezie; Pichardo-Almarza, Cesar

    2014-01-01

    The development of a new technology based on patient-specific modelling for personalised healthcare in the case of atherosclerosis is presented. Atherosclerosis is the main cause of death in the world and it has become a burden on clinical services as it manifests itself in many diverse forms, such as coronary artery disease, cerebrovascular disease/stroke and peripheral arterial disease. It is also a multifactorial, chronic and systemic process that lasts for a lifetime, putting enormous financial and clinical pressure on national health systems. In this Letter, the postulate is that the development of new technologies for healthcare using computer simulations can, in the future, be developed as in-silico management and support systems. These new technologies will be based on predictive models (including the integration of observations, theories and predictions across a range of temporal and spatial scales, scientific disciplines, key risk factors and anatomical sub-systems) combined with digital patient data and visualisation tools. Although the problem is extremely complex, a simulation workflow and an exemplar application of this type of technology for clinical use is presented, which is currently being developed by a multidisciplinary team following the requirements and constraints of the Vascular Service Unit at the University College Hospital, London.

  2. Numerical simulation for accuracy of velocity analysis in small-scale high-resolution marine multichannel seismic technology

    Science.gov (United States)

    Luo, Di; Cai, Feng; Wu, Zhiqiang

    2017-06-01

    When used with large energy sparkers, marine multichannel small-scale high-resolution seismic detection technology has a high resolution, high-detection precision, a wide applicable range, and is very flexible. Positive results have been achieved in submarine geological research, particularly in the investigation of marine gas hydrates. However, the amount of traveltime difference information is reduced for the velocity analysis under conditions of a shorter spread length, thus leading to poorer focusing of the velocity spectrum energy group and a lower accuracy of the velocity analysis. It is thus currently debatable whether the velocity analysis accuracy of short-arrangement multichannel seismic detection technology is able to meet the requirements of practical application in natural gas hydrate exploration. Therefore, in this study the bottom boundary of gas hydrates (Bottom Simulating Reflector, BSR) is used to conduct numerical simulation to discuss the accuracy of the velocity analysis related to such technology. Results show that a higher dominant frequency and smaller sampling interval are not only able to improve the seismic resolution, but they also compensate for the defects of the short-arrangement, thereby improving the accuracy of the velocity analysis. In conclusion, the accuracy of the velocity analysis in this small-scale, high-resolution, multi-channel seismic detection technology meets the requirements of natural gas hydrate exploration.

  3. Simulation and Experimental Determination of Technological Liquid Molding Parameters of Tubing Basalt Insulation

    Directory of Open Access Journals (Sweden)

    Yu. V. Badanina

    2015-01-01

    Full Text Available The article is dedicated to one of the most important and urgent tasks in mechanical engineering development - the creation of low-density and environmentally-friendly thermoinsulation from available cheap basalt fibers for products to operate at temperatures up to 700°C.One of the most effective applications of such thermo-insulation is to develop and provide highly porous coatings from short basalt fibers by liquid filtration for tubing (T to supply superheated up to 420° C steam under pressure of 35 MPa in the deep layers with severe highviscosity oil. Tubing with the short low-density basalt insulation can be used for a greater depth than the vacuum-insulated tubing, which are also called "thermo-cases", and do not fully meet business needs for long-term reliability of oil vacuum tubes, too large mass per unit length of their design and, as a consequence, the impossibility to use such pipes for deep wells.The aim of the work is to simulate a liquid filtration process of short fibers and determine technological parameters of producing thermal insulation coatings of tubing pipes from basalt fibers and mineral binder shaped as cylinders and cylindrical shells. The paper proposes a mathematical model of free filtration deposition of short fibers from liquid slurry, which describes dynamics of creating thermal insulation products and allows us to determine the rational parameters of their manufacturing process. It shows methods to improve the products quality while forming the thermal insulation by filtration through additional vacuum deposition of a filtrate chamber and the final prepressing of sediment layer, giving dimensions and shape to the final product.The paper defines a prescription hydro mass composition. It shows that to increase the compressive strength of highly fibrous rings and cylindrical shells it is necessary to use based on oxide А12O3 5-7% by weight mineral binder, which fixes basalt fibers in places of their contacts. It

  4. Airspace Technology Demonstration 2 (ATD-2) Integrated Surface and Airspace Simulation - Experiment Plan

    Science.gov (United States)

    Verma, Savita Arora; Jung, Yoon Chul

    2017-01-01

    This presentation describes the overview of the ATD-2 project and the integrated simulation of surface and airspace to evaluate the procedures of IADS system and evaluate surface metering capabilities via a high-fidelity human-in-the-loop simulation. Two HITL facilities, Future Flight Central (FFC) and Airspace Operations Laboratory (AOL), are integrated for simulating surface operations of the Charlotte-Douglas International Airport (CLT) and airspace in CLT TRACON and Washington Center.

  5. Avaliação "in loco" das perdas de protensão de cordoalhas engraxadas em lajes planas

    Directory of Open Access Journals (Sweden)

    S. J. Soares

    Full Text Available Este trabalho apresenta os resultados de um estudo sobre as perdas de protensão, medidas "in loco", de cordoalhas engraxadas em lajes planas. Essas lajes planas, com 17 centímetros de espessura e 350 m2 de área, fazem parte de um edifício para fins hoteleiros de 16 pavimentos. As forças de protensão foram medidas por células de carga colocadas nas proximidades da ancoragem ativa e da ancoragem passiva. As medidas de forças foram feitas desde a protensão até idades de 170 dias após esse instante. Os resultados revelam um coeficiente de atrito μ igual a 0,0528 bastante próximo ao valor apresentado pela norma brasileira NBR 6118: 0,05. Nas perdas pela acomodação da ancoragem os valores apurados foram bastante similares e em termos médios, essa perda correspondeu a 5,17% da força inicial de protensão. Os valores de força medidos mostram também que a perda de tensão na cordoalha, próximo à ancoragem passiva, é menor em relação à perda na ancoragem ativa. Até a idade de 170 dias, verificou-se uma perda média de 14% da força inicial de protensão.

  6. The use of scintimammography for detecting the recurrence of loco-regional breast cancer: histopathologically proven results.

    Science.gov (United States)

    Bongers, Vivian; Perre, Cornelis; de Hooge, Pieter

    2004-02-01

    99mTc tetrofosmin scintimammography has been shown to be an accurate diagnostic test in patients with a symptomatic breast lesion and for whom a non-diagnostic mammogram has been obtained. Since a physical examination and conventional imaging modalities have their limitations in the detection of recurrent breast cancer, and survival is related to the extent of recurrent disease, complementary imaging modalities are warranted. To evaluate the role of 99mTc tetrofosmin scintimammography in detecting the recurrence of loco-regional breast cancer. Fifty-four patients underwent 55 scintimammography studies because either there were clinical indications of breast metastases, or there was a recurrence of metastases in the chest wall, and/or an evaluation of axillary, parasternal, supraclavicular and/or infraclavicular lymph node metastases was required. Planar breast imaging was performed 10 min after intravenous injection of 700 MBq 99mTc tetrofosmin. 99mTc tetrofosmin scintimammography was diagnostic in 50 of the 55 studies. An unknown lung metastasis was detected in one patient, and an unknown bone metastasis of the sternum was detected in another. Tumour involvement remained undetected in one neck node metastasis. Three patients had false positive scintimammography results, with 99mTc tetrofosmin uptake in an axillary, infraclavicular and parasternal lymph node, respectively. A fourth patient showed 99mTc tetrofosmin uptake in the scar, which appeared to be an inflammatory lesion, proven by a histopathological biopsy and 1 year clinical follow-up. 99mTc tetrofosmin scintimammography accurately detected 100% of the local recurrences independently of the extent of the preceding surgical intervention. The sensitivity and specificity of the technique for the detection of regional recurrent disease were 93% and 90%, respectively. These results are substantially higher than those of other imaging modalities.

  7. The effect of loco-regional anaesthesia on motor activity induced by direct stimulation of the sciatic nerve in dogs.

    Science.gov (United States)

    Murdoch, A P; Michou, J N

    2016-03-01

    A prospective, randomised, blinded, case-controlled clinical study was designed using client-owned dogs undergoing unilateral pelvic limb orthopaedic surgery, to determine the effect on induced motor activity by electrical stimulation of the sciatic nerve distal to the site of local anaesthetic administration. Dogs were administered 0.5% bupivacaine either extradurally or via a femoral and transgluteal sciatic electrolocation-guided nerve block prior to pelvic limb surgery. Motor response to electrical stimulation of branches of the sciatic nerve was tested and the minimum current required to induce muscle twitch was recorded prior to bupivacaine administration. Provided sensory blockade had been deemed successful intraoperatively, testing was repeated postoperatively, with each dog acting as its own control. Paired t-tests were performed to compare pre- and postoperative minimum currents. Eleven dogs administered extradural and 11 dogs administered femoral and sciatic perineural bupivacaine were eligible for post-operative testing. All dogs displayed normal motor response to electrical stimulation of the sciatic nerve at both sites tested before and after bupivacaine administration. There was no significant difference in the minimum current required to induce muscle twitch between pre- and post-operative testing (P = 0.31 sciatic site, P = 0.36 peroneal site), nor between the two groups using different loco-regional anaesthetic techniques (minimum P = 0.13). This study shows that stimulation of the sciatic nerve distal to the site of bupivacaine administration induces motor activity, despite adequate sensory blockade. This is relevant in surgical cases where mechanical stimulation of the sciatic nerve might be expected and needs to be recognised to avoid postoperative neurapraxia.

  8. Comparisons of elastic and rigid blade-element rotor models using parallel processing technology for piloted simulations

    Science.gov (United States)

    Hill, Gary; Duval, Ronald W.; Green, John A.; Huynh, Loc C.

    1991-01-01

    A piloted comparison of rigid and aeroelastic blade-element rotor models was conducted at the Crew Station Research and Development Facility (CSRDF) at Ames Research Center. A simulation development and analysis tool, FLIGHTLAB, was used to implement these models in real time using parallel processing technology. Pilot comments and quantitative analysis performed both on-line and off-line confirmed that elastic degrees of freedom significantly affect perceived handling qualities. Trim comparisons show improved correlation with flight test data when elastic modes are modeled. The results demonstrate the efficiency with which the mathematical modeling sophistication of existing simulation facilities can be upgraded using parallel processing, and the importance of these upgrades to simulation fidelity.

  9. Comparison of elastic and rigid blade-element rotor models using parallel processing technology for piloted simulations

    Science.gov (United States)

    Hill, Gary; Du Val, Ronald W.; Green, John A.; Huynh, Loc C.

    1991-01-01

    A piloted comparison of rigid and aeroelastic blade-element rotor models was conducted at the Crew Station Research and Development Facility (CSRDF) at Ames Research Center. A simulation development and analysis tool, FLIGHTLAB, was used to implement these models in real time using parallel processing technology. Pilot comments and qualitative analysis performed both on-line and off-line confirmed that elastic degrees of freedom significantly affect perceived handling qualities. Trim comparisons show improved correlation with flight test data when elastic modes are modeled. The results demonstrate the efficiency with which the mathematical modeling sophistication of existing simulation facilities can be upgraded using parallel processing, and the importance of these upgrades to simulation fidelity.

  10. Cost-effective and low-technology options for simulation and training in neonatology.

    Science.gov (United States)

    Bruno, Christie J; Glass, Kristen M

    2016-11-01

    The purpose of this review is to explore low-cost options for simulation and training in neonatology. Numerous cost-effective options exist for simulation and training in neonatology. Lower cost options are available for teaching clinical skills and procedural training in neonatal intubation, chest tube insertion, and pericardiocentesis, among others. Cost-effective, low-cost options for simulation-based education can be developed and shared in order to optimize the neonatal simulation training experience. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Diagnosing the Local Land-Atmosphere Coupling (LoCo) in Models and Observations: A Study of Dry/Wet Extremes in the U. S. Southern Great Plains

    Science.gov (United States)

    Santanello, J. A.; Peters-Lidard, C. D.; Kumar, S.; Dong, X.; Kennedy, A. D.

    2010-12-01

    Land-atmosphere interactions play a critical role in determining the diurnal evolution of both planetary boundary layer (PBL) and land surface temperature and moisture states. The degree of coupling between the land surface and PBL in numerical weather prediction and climate models remains largely unexplored and undiagnosed due to the complex interactions and feedbacks present across a range of scales. Further, uncoupled systems or experiments (e.g., the Project for Intercomparison of Land Parameterization Schemes, PILPS) may lead to inaccurate water and energy cycle process understanding by neglecting feedback processes such as PBL-top entrainment. In this study, a framework for diagnosing local land-atmosphere coupling (LoCo) is presented using a coupled mesoscale model with a suite of PBL and land surface model (LSM) options along with observations during the summers of 2006/7 in the U.S. Southern Great Plains. Specifically, the Weather Research and Forecasting (WRF) model has been coupled to NASA's Land Information System (LIS), which provides a flexible and high-resolution representation and initialization of land surface physics and states. A range of diagnostics exploring the links and feedbacks between soil moisture and precipitation are examined for the dry/wet extremes of this region, along with the sensitivity of PBL-LSM coupling to perturbations in soil moisture. As such, this methodology provides a potential pathway to study factors controlling local land-atmosphere coupling (LoCo) using the LIS-WRF system, which is serving as a testbed for LoCo experiments to evaluate coupling diagnostics within the community.

  12. Air Vehicle Technology Integration Program (AVTIP) Delivery Order 0008: Open Control Platform (OCP) Software Enabled Control (SEC) Hardware in the Loop Simulation Program

    Science.gov (United States)

    2004-07-01

    AFRL-VA-WP-TR-2006-3074 AIR VEHICLE TECHNOLOGY INTEGRATION PROGRAM (AVTIP) Delivery Order 0008: Open Control Platform (OCP) Software Enabled...especially the case since the NGC technology software for SEC was completely developed in the Simulink environment. The OCP middleware was put through...STANLEY H. PRUETT GARY K. HELLMANN, Chief Aerospace Vehicles Technology Aerospace Vehicles Technology Assessment & Simulation Branch Assessment

  13. B-1 Systems Approach to Training. Simulation Technology Assessment Report (STAR)

    Science.gov (United States)

    1975-07-01

    Cinematic Simulators in Pilot Training. Anacapa Sciences, Inc. Report NAVTRAEQUIPCEN 70-C-0305-1, March 1973. (AD 766 507). 5-16 ■PI mumm** I...Assn., San Francisco, Calif., May 5-8, 1969. Ruocco, J.N., Vitale, P.A., Benfari, R.C., Kinetic Cueing in Simulated Carrier Approaches. Navy

  14. New frontiers in medical education: simulation technology at Campbell University School of Osteopathic Medicine.

    Science.gov (United States)

    Maddox, Ronald W; Schmid, Robert J

    2014-01-01

    Campbell University School of Osteopathic Medicine is using a variety of medical simulation systems in the training of its medical students. The simulators allow students to learn and practice skills in a controlled environment, and they enable faculty to challenge students with a broader range of conditions than might ordinarily be encountered during medical training.

  15. Dose-Response Relationship between Radiation Dose and Loco-regional Control in Patients with Stage II-III Esophageal Cancer Treated with Definitive Chemoradiotherapy.

    Science.gov (United States)

    Kim, Hyun Ju; Suh, Yang-Gun; Lee, Yong Chan; Lee, Sang Kil; Shin, Sung Kwan; Cho, Byung Chul; Lee, Chang Geol

    2017-07-01

    The correlation between radiation dose and loco-regional control (LRC) was evaluated in patients with stage II-III esophageal cancer treated with definitive concurrent chemoradiotherapy (CRT). Medical records of 236 stage II-III esophageal cancer patients treated with definitive CRT at Yonsei Cancer Center between 1994 and 2013 were retrospectively reviewed. Among these, 120 received a radiation dose of 60 Gy) is associated with increased LRC, PFS, and OS in patients with stage II-III esophageal cancer treated with definitive CRT.

  16. Herança e ligação em locos de isoenzimas em Genipa americana L. Inheritance and linkage in isozymes loci of Genipa americana L.

    Directory of Open Access Journals (Sweden)

    Alexandre Magno SEBBENN

    2004-06-01

    Full Text Available A herança e a ligação foram estudadasem quatro locos polimórficos (6pghd-1, Pgi-2,Mdh-1 e Mdh-2 de três sistemas isoenzimáticos deGenipa americana, analisados por eletroforesehorizontal em gel de amido, usando tecidoscoletados de quinze progênies de polinização aberta,procedentes de Moji-Guaçu, Estado de São Paulo.Esses locos segregaram de dois a três alelos.A segregação nesses locos foi homogênea entreárvores. Contudo, existem desvios significativos dasegregação esperada 1:1 para algumas árvores emalguns locos. Desvios significativos da razão desegregação esperada 1:1 foram detectados noslocos Mdh-2 e 6pgdh-1. Não foram detectadasevidências de ligação entre nenhum dos pares delocos avaliados em G. americana e esses podemser utilizados sem restrição para estudos do sistemade reprodução, diversidade e estrutura genética depopulações da espécie.Inheritance and linkage for fourpolymorphic loci (6pghd-1, Pgi-2, Mdh-1 andMdh-2 from three enzyme systems in Genipaamericana were analyzed by horizontal starch gelelectrophoresis using tissues collected from fiftyopen-pollinated families in Moji-Guaçu, São PauloState. These allozyme loci have segregated fromtwo to four alleles per polymorphic locus. Genesegregation on those loci was homogeneous amongtrees. However, there were significant deviationsfrom the expected segregation ratios on some lociand some individual trees. In addition, Mdh-2 and6pgdh-1 loci have shown significant deviationsfrom the 1:1 expected segregation ratio. Linkagedisequilibrium evidences were not detected betweenany two pairs of loci from G. americana and thosecan be used with no restriction to study the matingsystem, genetic diversity, and genetic structure onthe species.

  17. Caracterização molecular do loco Red associado a resistência ao oídio da soja

    OpenAIRE

    Pereira,Alan Alves

    2015-01-01

    Diante da importância da cultura da soja e da severidade do oídio em causar danos, este estudo teve como principais objetivos avaliar linhagens endogâmicas recombinantes de soja para resistência a este patógeno e caracterizar molecularmente os genes de resistência localizados na região de mapeamento do loco Red, que confere resistência ao oídio em soja. Avaliações fenotípicas realizadas em 109 famílias derivadas do cruzamento entre o acesso BRI01-22106 (Resistente) e o acesso PI200487 (Suscet...

  18. The development of an autonomous rendezvous and docking simulation using rapid integration and prototyping technology

    Science.gov (United States)

    Shackelford, John H.; Saugen, John D.; Wurst, Michael J.; Adler, James

    1991-01-01

    A generic planar 3 degree of freedom simulation was developed that supports hardware in the loop simulations, guidance and control analysis, and can directly generate flight software. This simulation was developed in a small amount of time utilizing rapid prototyping techniques. The approach taken to develop this simulation tool, the benefits seen using this approach to development, and on-going efforts to improve and extend this capability are described. The simulation is composed of 3 major elements: (1) Docker dynamics model, (2) Dockee dynamics model, and (3) Docker Control System. The docker and dockee models are based on simple planar orbital dynamics equations using a spherical earth gravity model. The docker control system is based on a phase plane approach to error correction.

  19. The potential environmental gains from recycling waste plastics: simulation of transferring recycling and recovery technologies to Shenyang, China.

    Science.gov (United States)

    Chen, Xudong; Xi, Fengming; Geng, Yong; Fujita, Tsuyoshi

    2011-01-01

    With the increasing attention on developing a low-carbon economy, it is necessary to seek appropriate ways on reducing greenhouse gas (GHG) emissions through innovative municipal solid waste management (MSWM), such as urban symbiosis. However, quantitative assessments on the environmental benefits of urban symbiosis, especially in developing countries, are limited because only a limited number of planned synergistic activities have been successful and it is difficult to acquire detailed inventory data from private companies. This paper modifies and applies a two-step simulation system and used it to assess the potential environmental benefits, including the reduction of GHG emissions and saving of fossil fuels, by employing various Japanese plastics recycling/energy-recovery technologies in Shenyang, China. The results showed that among various recycling/energy-recovery technologies, the mechanical waste plastics recycling technology, which produces concrete formwork boards (NF boards), has the greatest potential in terms of reducing GHG emissions (1.66 kg CO(2)e/kg plastics), whereas the technology for the production of refuse plastic fuel (RPF) has the greatest potential on saving fossil fuel consumption (0.77 kg ce/kg-plastics). Additional benefits can be gained by applying combined technologies that cascade the utilization of waste plastics. Moreover, the development of clean energy in conjunction with the promotion of new waste plastics recycling programs could contribute to additional reductions in GHG emissions and fossil fuel consumption.

  20. Vertical flight training: An overview of training and flight simulator technology with emphasis on rotary-wing requirements

    Science.gov (United States)

    Alderete, Thomas S.; Ascencio-Lee, Carmen E.; Bray, Richard; Carlton, John; Dohme, Jack; Eshow, Michelle M.; Francis, Stephen; Lee, Owen M.; Lintern, Gavan; Lombardo, David A.

    1994-01-01

    The principal purpose of this publication is to provide a broad overview of the technology that is relevant to the design of aviation training systems and of the techniques applicable to the development, use, and evaluation of those systems. The issues addressed in our 11 chapters are, for the most part, those that would be expected to surface in any informed discussion of the major characterizing elements of aviation training systems. Indeed, many of the same facets of vertical-flight training discussed were recognized and, to some extent, dealt with at the 1991 NASA/FAA Helicopter Simulator Workshop. These generic topics are essential to a sound understanding of training and training systems, and they quite properly form the basis of any attempt to systematize the development and evaluation of more effective, more efficient, more productive, and more economical approaches to aircrew training. Individual chapters address the following topics: an overview of the vertical flight industry: the source of training requirements; training and training schools: meeting current requirements; training systems design and development; transfer of training and cost-effectiveness; the military quest for flight training effectiveness; alternative training systems; training device manufacturing; simulator aero model implementation; simulation validation in the frequency domain; cockpit motion in helicopter simulation; and visual space perception in flight simulators.

  1. Early bedside care during preclinical medical education: can technology-enhanced patient simulation advance the Flexnerian ideal?

    Science.gov (United States)

    Gordon, James A; Hayden, Emily M; Ahmed, Rami A; Pawlowski, John B; Khoury, Kimberly N; Oriol, Nancy E

    2010-02-01

    Flexner wanted medical students to study at the patient bedside-a remarkable innovation in his time-so that they could apply science to clinical care under the watchful eye of senior physicians. Ever since his report, medical schools have reserved the latter years of their curricula for such an "advanced" apprenticeship, providing clinical clerkship experiences only after an initial period of instruction in basic medical sciences. Although Flexner codified the segregation of preclinical and clinical instruction, he was committed to ensuring that both domains were integrated into a modern medical education. The aspiration to fully integrate preclinical and clinical instruction continues to drive medical education reform even to this day. In this article, the authors revisit the original justification for sequential preclinical-clinical instruction and argue that modern, technology-enhanced patient simulation platforms are uniquely powerful for fostering simultaneous integration of preclinical-clinical content in a way that Flexner would have applauded. To date, medical educators tend to focus on using technology-enhanced medical simulation in clinical and postgraduate medical education; few have devoted significant attention to using immersive clinical simulation among preclinical students. The authors present an argument for the use of dynamic robot-mannequins in teaching basic medical science, and describe their experience with simulator-based preclinical instruction at Harvard Medical School. They discuss common misconceptions and barriers to the approach, describe their curricular responses to the technique, and articulate a unifying theory of cognitive and emotional learning that broadens the view of what is possible, feasible, and desirable with simulator-based medical education.

  2. A Virtual Simulation Environment for Lunar Rover: Framework and Key Technologies

    Directory of Open Access Journals (Sweden)

    Yan-chun Yang

    2008-11-01

    Full Text Available Lunar rover development involves a large amount of validation works in realistic operational conditions, including its mechanical subsystem and on-board software. Real tests require equipped rover platform and a realistic terrain. It is very time consuming and high cost. To improve the development efficiency, a rover simulation environment called RSVE that affords real time capabilities with high fidelity has been developed. It uses fractional Brown motion (fBm technique and statistical properties to generate lunar surface. Thus, various terrain models for simulation can be generated through changing several parameters. To simulate lunar rover evolving on natural and unstructured surface with high realism, the whole dynamics of the multi-body systems and complex interactions with soft ground is integrated in this environment. An example for path planning algorithm and controlling algorithm testing in this environment is tested. This simulation environment runs on PC or Silicon Graphics.

  3. Research and Analysis of Possible Solutions for Navy-Simulated Training Technology

    Science.gov (United States)

    2015-03-01

    143 Figure 44. 1.1.2-Simulate Red Forces RPG Weapon IDEF0 ..........................................143 Figure 45. 1.1.3-Transmit...Hull Inflatable Boats ROE Rules of Engagement RPG Rocket-Propelled Grenade SAG Surface Action Group SAT Small Arms Transmitter xiv SME Subject...characteristics 0.4 Shall simulate Red force ship’s RPG weapons 90% 95% characteristics E.1 Shall establish a secure local area network 95% 100% capable of

  4. Utilization of simulation for the introduction of new software technology to the clinical setting.

    Science.gov (United States)

    Richie, Eugene; Dove, Conrad; Crowe, Shannon L; DeArment, Vickie; Manwiller, Jimmie; Wallace, Michael; Thiel, David D

    2014-09-01

    ProVation Medical documentation software was introduced in our Department of Gastroenterology (GI). We evaluated the use of a simulation module to improve the introduction of new documentation software into a tertiary care center GI department. Train-the-trainer education was provided by the vendor of the new documentation module. A simulation module was developed to simulate the preparatory, intraprocedural, and postprocedure phase of active utilization of the software. A standardized patient (SP)/medical actor was used for provision of data to be entered in to the ProVation Medical preprocedure module. A procedural suite was configured to allow for staff to assume their roles during endoscopic cases. A checklist of key activities was used by observers during the training. A postscenario evaluation document was collected for perceptions of training. Twenty-one GI nurses and technicians spent 3 hours in groups of 7 over a 3-day period completing activities commensurate with these procedural phases. Nineteen of 21 learners felt the simulation was nonthreatening, and the same number gave the course an overall 5/5 rating. There were no specimen labeling errors, patient identification errors, or sentinel events related to the software rollout. All learners felt that physician involvement in the simulation would have been beneficial. Simulation can be used to improve the rollout of new software in a tertiary care center. Staff satisfaction associated with this type of learning activity was high, and a communicated level of comfort was achieved as a result of the simulation-based experiential learning.

  5. Application and numerical simulation research on biomimetic drag-reducing technology for gas pipelining

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Deyuan; Luo Yuehao; Chen Huawei [Beihang Univ., Beijing (China). School of Mechanical Engineering and Automation

    2011-06-15

    For the purpose of increasing the transmission capacity of gas pipelines, the internal coating technology has been vastly put into application, and a remarkable benefit has been achieved so far. However, with the reduction of wall roughness, the small convex parts are all completely submerged in the viscous sublayer, the gas pipeline becomes a 'hydraulic smooth pipe', even by smoothing the coating surface further, it is difficult to reduce wall friction. Therefore, in order to increase the transportation capacity on the basis of internal coating, the new methods and technologies should be researched and investigated, and perhaps, the biomimetic drag-reducing technology is a good approach. In this paper, according to the planning parameters of the second pipeline of the West-to-East gas transmission project, the best drag reducing effect grooves are calculated and designed, and based on the characteristics and properties of internal coating (AW-01 epoxy resin), the Pre-Cured Micro- Rolling Technology (PCMRT) is discussed and presented, the rolling equipment is also designed and analyzed, the rolling process can be easily added on the available production line. Aiming at the field operating parameters of the gas pipeline in China, and the drag-reducing effect of the grooved surface is analyzed and discussed comprehensively. In addition, the economic benefit of adopting the biomimetic drag reduction technology is investigated. (orig.)

  6. Postoperative radiotherapy appeared to improve the disease free survival rate of patients with extrahepatic bile duct cancer at high risk of loco-regional recurrence

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mi Young; Kim, Jin Hee; Kim, Yong Hoon [Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu (Korea, Republic of); Byun, Sang Jun [Dept. of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

    2016-12-15

    To investigate the outcomes of postoperative radiotherapy (RT), in patients with extrahepatic bile duct (EHBD) cancer by comparing the survival rate between patients undergoing surgery alone or surgery plus postoperative RT, and to identify the prognostic factors affecting survival. Between 2000 and 2013, 52 patients with EHBD cancer underwent surgical resection. Of these, 33 patients did not receive postoperative RT (group I), and 19 patients did (group II). R1 resection was significantly more frequent in group II. The median radiation dose was 5,040 cGy. The 3-year overall survival (OS) rate for group I and group II was 38% and 56%, respectively (p = 0.274). The 3-year disease free survival (DFS) rate for group I and group II was 20% and 31%, respectively (p = 0.049), and the 3-year loco-regional recurrence free survival (LRFS) rates were 19% and 58%, respectively (p = 0.002). Multivariate analyses showed that postoperative RT and lymphovascular invasion were independent prognostic factors for DFS and LRFS. Overall, 42 patients (80%) experienced treatment failure. Distant metastasis was the predominant pattern of failure in group II. Postoperative RT after surgical resection appeared to improve the loco-regional control and DFS rate. More effort is needed to reduce distant metastasis, the major pattern of failure, in patients who receive postoperative RT.

  7. Regulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS protein.

    Science.gov (United States)

    Kaplow, Margarita E; Korayem, Adam H; Venkatesh, Tadmiri R

    2008-04-01

    Glia mediate a vast array of cellular processes and are critical for nervous system development and function. Despite their immense importance in neurobiology, glia remain understudied and the molecular mechanisms that direct their differentiation are poorly understood. Rap/Fzr is the Drosophila homolog of the mammalian Cdh1, a regulatory subunit of the anaphase-promoting complex/cyclosome (APC/C). APC/C is an E3 ubiquitin ligase complex well characterized for its role in cell cycle progression. In this study, we have uncovered a novel cellular role for Rap/Fzr. Loss of rap/fzr function leads to a marked increase in the number of glia in the nervous system of third instar larvae. Conversely, ectopic expression of UAS-rap/fzr, driven by repo-GAL4, results in the drastic reduction of glia. Data from clonal analyses using the MARCM technique show that Rap/Fzr regulates the differentiation of surface glia in the developing larval nervous system. Our genetic and biochemical data further indicate that Rap/Fzr regulates glial differentiation through its interaction with Loco, a regulator of G-protein signaling (RGS) protein and a known effector of glia specification. We propose that Rap/Fzr targets Loco for ubiquitination, thereby regulating glial differentiation in the developing nervous system.

  8. Montecarlo Simulation Applied to Measurement of the Impact of the Smart Antenna Technology in Digital Cellular Systems

    Directory of Open Access Journals (Sweden)

    Castañeda-Camacho Josefina

    2015-03-01

    Full Text Available The smart antenna technology has received increasing interest due to its capability for improving the performance of wireless radio systems. In this work, we studied the throughput maximization in a digital cellular system when a smart antenna array is implemented. We focus, in the study of the downlink of a 3G cellular system and consider a packet data direct-sequence code division, multiple access (DS-CDMA. Our methodology is based on the Monte Carlo simulation technique, and it is used to show that it is possible to obtain a significant increment in the throughput of the system due to the switched beam smart antenna array. From our results we conclude that it is feasible to consider the application of this technology in 4G environments.

  9. Accurate SPICE Modeling of Poly-silicon Resistor in 40nm CMOS Technology Process for Analog Circuit Simulation

    Directory of Open Access Journals (Sweden)

    Sun Lijie

    2015-01-01

    Full Text Available In this paper, the SPICE model of poly resistor is accurately developed based on silicon data. To describe the non-linear R-V trend, the new correlation in temperature and voltage is found in non-silicide poly-silicon resistor. A scalable model is developed on the temperature-dependent characteristics (TDC and the temperature-dependent voltage characteristics (TDVC from the R-V data. Besides, the parasitic capacitance between poly and substrate are extracted from real silicon structure in replacing conventional simulation data. The capacitance data are tested through using on-wafer charge-induced-injection error-free charge-based capacitance measurement (CIEF-CBCM technique which is driven by non-overlapping clock generation circuit. All modeling test structures are designed and fabricated through using 40nm CMOS technology process. The new SPICE model of poly-silicon resistor is more accurate to silicon for analog circuit simulation.

  10. Technology.

    Science.gov (United States)

    Online-Offline, 1998

    1998-01-01

    Focuses on technology, on advances in such areas as aeronautics, electronics, physics, the space sciences, as well as computers and the attendant progress in medicine, robotics, and artificial intelligence. Describes educational resources for elementary and middle school students, including Web sites, CD-ROMs and software, videotapes, books,…

  11. Community Petascale Project for Accelerator Science and Simulation: Advancing Computational Science for Future Accelerators and Accelerator Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Spentzouris, P.; /Fermilab; Cary, J.; /Tech-X, Boulder; McInnes, L.C.; /Argonne; Mori, W.; /UCLA; Ng, C.; /SLAC; Ng, E.; Ryne, R.; /LBL, Berkeley

    2011-11-14

    The design and performance optimization of particle accelerators are essential for the success of the DOE scientific program in the next decade. Particle accelerators are very complex systems whose accurate description involves a large number of degrees of freedom and requires the inclusion of many physics processes. Building on the success of the SciDAC-1 Accelerator Science and Technology project, the SciDAC-2 Community Petascale Project for Accelerator Science and Simulation (ComPASS) is developing a comprehensive set of interoperable components for beam dynamics, electromagnetics, electron cooling, and laser/plasma acceleration modelling. ComPASS is providing accelerator scientists the tools required to enable the necessary accelerator simulation paradigm shift from high-fidelity single physics process modeling (covered under SciDAC1) to high-fidelity multiphysics modeling. Our computational frameworks have been used to model the behavior of a large number of accelerators and accelerator R&D experiments, assisting both their design and performance optimization. As parallel computational applications, the ComPASS codes have been shown to make effective use of thousands of processors. ComPASS is in the first year of executing its plan to develop the next-generation HPC accelerator modeling tools. ComPASS aims to develop an integrated simulation environment that will utilize existing and new accelerator physics modules with petascale capabilities, by employing modern computing and solver technologies. The ComPASS vision is to deliver to accelerator scientists a virtual accelerator and virtual prototyping modeling environment, with the necessary multiphysics, multiscale capabilities. The plan for this development includes delivering accelerator modeling applications appropriate for each stage of the ComPASS software evolution. Such applications are already being used to address challenging problems in accelerator design and optimization. The ComPASS organization

  12. Modeling and simulation of a residential micro-CHP system based on HT-PEMFC technology

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2009-01-01

    Combined-heat-and-power (CHP) technology is a well known and proved method to produce simultaneously power and heat at high efficiencies. This can be further improved by the introduction of a novel micro-CHP residential system based on High Temperature-Proton Exchange Membrane Fuel Cell (HT......-PEMFC). The HT-PEMFC (based on PBI-membrane technology) operates at temperatures near 200oC, and this can be an ideal match for cogeneration residential systems. The proposed system provides electric power, hot water, and space heating for a typical household (1-5 kWe, 5-10 kWth). The micro-CHP system...

  13. Application of Java Technology to Simulation of Transient Effects in Accelerator Magnets

    CERN Document Server

    CERN. Geneva

    2017-01-01

    Superconducting magnets are one of the key building blocks of modern high-energy particle accelerators. Operating at extremely low temperatures (1.9 K), superconducting magnets produce high magnetic field needed to control the trajectory of beams travelling at nearly the speed of light. With high performance comes considerable complexity represented by several coupled physical domains characterized by multi-rate and multi-scale behaviour. The full exploitation of the LHC, as well as the design of its upgrades and future accelerators calls for more accurate simulations. With such a long-term vision in mind, the STEAM (Simulation of Transient Effects in Accelerator Magnets) project has been establish and is based on two pillars: (i) models developed with optimised solvers for particular sub-problems, (ii) coupling interfaces allowing to exchange information between the models. In order to tackle these challenges and develop a maintainable and extendable simulation framework, a team of developers implemented a ...

  14. Advances in Systems and Technologies Toward Interopoerating Operational Military C2 and Simulation Systems

    Science.gov (United States)

    2014-06-01

    terrestre  (APLET).     APLET  is  a  French  Ministry  of  Defense  (MoD)  Research  and...of   representing   ground   forces   at   need).  JSAF  interacted  with  the  other  simulators   via  DIS  and...standard   simulation   for   collective   training.  OneSAF  was   linked  to  the  US  C2  system   via  JC3IEDM

  15. The Dust Management Project: Characterizing Lunar Environments and Dust, Developing Regolith Mitigation Technology and Simulants

    Science.gov (United States)

    Hyatt, Mark J.; Straka, Sharon A.

    2010-01-01

    A return to the Moon to extend human presence, pursue scientific activities, use the Moon to prepare for future human missions to Mars, and expand Earth?s economic sphere, will require investment in developing new technologies and capabilities to achieve affordable and sustainable human exploration. From the operational experience gained and lessons learned during the Apollo missions, conducting long-term operations in the lunar environment will be a particular challenge, given the difficulties presented by the unique physical properties and other characteristics of lunar regolith, including dust. The Apollo missions and other lunar explorations have identified significant lunar dust-related problems that will challenge future mission success. Comprised of regolith particles ranging in size from tens of nanometers to microns, lunar dust is a manifestation of the complex interaction of the lunar soil with multiple mechanical, electrical, and gravitational effects. The environmental and anthropogenic factors effecting the perturbation, transport, and deposition of lunar dust must be studied in order to mitigate it?s potentially harmful effects on exploration systems and human explorers. The Dust Management Project (DMP) is tasked with the evaluation of lunar dust effects, assessment of the resulting risks, and development of mitigation and management strategies and technologies related to Exploration Systems architectures. To this end, the DMP supports the overall goal of the Exploration Technology Development Program (ETDP) of addressing the relevant high priority technology needs of multiple elements within the Constellation Program (CxP) and sister ETDP projects. Project scope, plans, and accomplishments will be presented.

  16. Learning with Web Tools, Simulations, and Other Technologies in Science Classrooms

    Science.gov (United States)

    Campbell, Todd; Wang, Shaing Kwei; Hsu, Hui-Yin; Duffy, Aaron M.; Wolf, Paul G.

    2010-10-01

    This position paper proposes the enhancement of teacher and student learning in science classrooms by tapping the enormous potential of information communication and technologies (ICTs) as cognitive tools for engaging students in scientific inquiry. This paper serves to challenge teacher-held assumptions about students learning science `from technology' with a framework and examples of students learning science `with technology'. Whereas a high percentage of students are finding their way in using ICTs outside of school, for the most part they currently are not doing so inside of school in ways that they find meaningful and relevant to their lives. Instead, the pedagogical approaches that are most often experienced are out-of-step with how students use ICTs outside of schools and are not supportive of learning framed by constructivism. Here we describe a theoretical and pedagogical foundation for better connecting the two worlds of students' lives: life in school and life outside of school. This position paper is in response to the changing landscape of students' lives. The position is transformative in nature because it proposes the use of cyber-enabled resources for cultivating and leveraging students new literacy skills by learning `with technology' to enhance science learning.

  17. Simulating the effect on the energy efficiency of smart grid technologies

    NARCIS (Netherlands)

    Molderink, Albert; Bosman, M.G.C.; Bakker, Vincent; Hurink, Johann L.; Smit, Gerardus Johannes Maria

    2009-01-01

    The awareness of the greenhousegas effect and rising energy prices lead to initiatives to improve energy ef��?ciency. These initiatives range from micro-generation, energy storage and ef��?cient appliances to controllers with optimization objectives. Although these technologies are promising, their

  18. Decomposition strategies in the problems of simulation of additive laser technology processes

    Science.gov (United States)

    Khomenko, M. D.; Dubrov, A. V.; Mirzade, F. Kh.

    2016-11-01

    The development of additive technologies and their application in industry is associated with the possibility of predicting the final properties of a crystallized added material. This paper describes the problem characterized by a dynamic and spatially nonuniform computational complexity, which, in the case of uniform decomposition of a computational domain, leads to an unbalanced load on computational cores. The strategy of partitioning of the computational domain is used, which minimizes the CPU time losses in the serial computations of the additive technological process. The chosen strategy is optimal from the standpoint of a priori unknown dynamic computational load distribution. The scaling of the computational problem on the cluster of the Institute on Laser and Information Technologies (RAS) that uses the InfiniBand interconnect is determined. The use of the parallel code with optimal decomposition made it possible to significantly reduce the computational time (down to several hours), which is important in the context of development of the software package for support of engineering activity in the field of additive technology.

  19. Events Management Education through CD-ROM Simulation at Victoria University of Technology.

    Science.gov (United States)

    Perry, Marcia; And Others

    There has been a rapid growth in the events industry in Victoria and Australia over the past five years with an increase in large scale events--resulting in substantive economic impact. The growth in events in Australia is projected to continue to beyond 2001. The Department of Management at Victoria University of Technology (VU) received a…

  20. Integrating a Head-Up Display with Dome Visual Simulation Technology.

    Science.gov (United States)

    1986-12-01

    Infinity-Optics System windows, provide an observer with an increased sense of "volume," depth of field, and/or realism . In fact, some experimenters...Environment Simulation Techniques. Washington, DC: National Aeronautics and Space Administration. Lipton, L. (1982). Foundations of the stereoscopic cinema (pp

  1. Foresighting new technological systems using simulation - application on e-mobility

    DEFF Research Database (Denmark)

    Spangenberg, Felix; Göhlich, Dietmar; Rohrbeck, René

    2013-01-01

    key performance indicators (KPIs). A Monte Carlo Simulations delivers the prognoses of the KPIs based on a system model and stochastic input parameters. The new foresight methodology is applied to identify the best future electric bus system for the city of Berlin which will be realized within the e...

  2. Technology Evaluation of Process Configurations for Second Generation Bioethanol Production using Dynamic Model-based Simulations

    DEFF Research Database (Denmark)

    Morales Rodriguez, Ricardo; Meyer, Anne S.; Gernaey, Krist

    2011-01-01

    An assessment of a number of different process flowsheets for bioethanol production was performed using dynamic model-based simulations. The evaluation employed diverse operational scenarios such as, fed-batch, continuous and continuous with recycle configurations. Each configuration was evaluate...

  3. Simulation

    CERN Document Server

    Ross, Sheldon

    2006-01-01

    Ross's Simulation, Fourth Edition introduces aspiring and practicing actuaries, engineers, computer scientists and others to the practical aspects of constructing computerized simulation studies to analyze and interpret real phenomena. Readers learn to apply results of these analyses to problems in a wide variety of fields to obtain effective, accurate solutions and make predictions about future outcomes. This text explains how a computer can be used to generate random numbers, and how to use these random numbers to generate the behavior of a stochastic model over time. It presents the statist

  4. Fabrication and simulation of single crystal p-type Si nanowire using SOI technology

    Energy Technology Data Exchange (ETDEWEB)

    Dehzangi, Arash, E-mail: arashd53@hotmail.com [Institute of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Larki, Farhad [Institute of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Naseri, Mahmud G. [Department of Physics, Faculty of Science, Malayer University, Malayer, Hamedan (Iran, Islamic Republic of); Navasery, Manizheh [Department of Physics, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia); Majlis, Burhanuddin Y.; Razip Wee, Mohd F. [Institute of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Halimah, M.K. [Department of Physics, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia); Islam, Md. Shabiul; Md Ali, Sawal H. [Institute of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Saion, Elias [Department of Physics, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia)

    2015-04-15

    Highlights: • Single crystal silicon nanowire is fabricated on Si on insulator substrate, using atomic force microscope (AFM) nanolithography and KOH + IPA chemical wet etching. • Some of major parameters in fabrication process, such as writing speed and applied voltage along with KOH etching depth are investigated, and then the I–V characteristic of Si nanowires is measured. • For better understanding of the charge transmission through the nanowire, 3D-TCAD simulation is performed to simulate the Si nanowires with the same size of the fabricated ones, and variation of majority and minority carriers, hole quasi-Fermi level and generation/recombination rate are investigated. - Abstract: Si nanowires (SiNWs) as building blocks for nanostructured materials and nanoelectronics have attracted much attention due to their major role in device fabrication. In the present work a top-down fabrication approach as atomic force microscope (AFM) nanolithography was performed on Si on insulator (SOI) substrate to fabricate a single crystal p-type SiNW. To draw oxide patterns on top of the SOI substrate local anodic oxidation was carried out by AFM in contact mode. After the oxidation procedure, an optimized solution of 30 wt.% KOH with 10 vol.% IPA for wet etching at 63 °C was applied to extract the nanostructure. The fabricated SiNW had 70–85 nm full width at half maximum width, 90 nm thickness and 4 μm length. The SiNW was simulated using Sentaurus 3D software with the exact same size of the fabricated device. I–V characterization of the SiNW was measured and compared with simulation results. Using simulation results variation of carrier's concentrations, valence band edge energy and recombination generation rate for different applied voltage were investigated.

  5. Assessment of a generalizable methodology to assess learning from manikin-based simulation technology.

    Science.gov (United States)

    Giuliano, Dominic A; McGregor, Marion

    2014-01-01

    Objective : This study combined a learning outcomes-based checklist and salient characteristics derived from wisdom-of-crowds theory to test whether differing groups of judges (diversity maximized versus expertise maximized) would be able to appropriately assess videotaped, manikin-based simulation scenarios. Methods : Two groups of 3 judges scored 9 videos of interns managing a simulated cardiac event. The first group had a diverse range of knowledge of simulation procedures, while the second group was more homogeneous in their knowledge and had greater simulation expertise. All judges viewed 3 types of videos (predebriefing, postdebriefing, and 6 month follow-up) in a blinded fashion and provided their scores independently. Intraclass correlation coefficients (ICCs) were used to assess the reliability of judges as related to group membership. Scores from each group of judges were averaged to determine the impact of group on scores. Results : Results revealed strong ICCs for both groups of judges (diverse, 0.89; expert, 0.97), with the diverse group of judges having a much wider 95% confidence interval for the ICC. Analysis of variance of the average checklist scores indicated no significant difference between the 2 groups of judges for any of the types of videotapes assessed (F = 0.72, p = .4094). There was, however, a statistically significant difference between the types of videos (F = 14.39, p = .0004), with higher scores at the postdebrief and 6-month follow-up time periods. Conclusions : Results obtained in this study provide optimism for assessment procedures in simulation using learning outcomes-based checklists and a small panel of judges.

  6. ARC+(Registered Trademark) and ARC PC Welding Simulators: Teach Welders with Virtual Interactive 3D Technologies

    Science.gov (United States)

    Choquet, Claude

    2011-01-01

    123 Certification Inc., a Montreal based company, has developed an innovative hands-on welding simulator solution to help build the welding workforce in the most simple way. The solution lies in virtual reality technology, which has been fully tested since the early 90's. President and founder of 123 Certification Inc., Mr. Claude Choquet Ing. Msc. IWE. acts as a bridge between the welding and the programming world. Working in these fields for more than 20 years. he has filed 12 patents world-wide for a gesture control platform with leading edge hardware related to simulation. In the summer of 2006. Mr Choquet was proud to be invited to the annual IIW International Weld ing Congress in Quebec City to launch the ARC+ welding simulator. A 100% virtual reality system and web based training center was developed to simulate multi process. multi-materiaL multi-position and multi pass welding. The simulator is intended to train welding students and apprentices in schools or industries. The welding simulator is composed of a real welding e[eetrode holder (SMAW-GTAW) and gun (GMAW-FCAW). a head mounted display (HMD), a 6 degrees of freedom tracking system for interaction between the user's hands and head. as well as external audio speakers. Both guns and HMD are interacting online and simultaneously. The welding simulation is based on the law of physics and empirical results from detailed analysis of a series of welding tests based on industrial applications tested over the last 20 years. The simulation runs in real-time, using a local logic network to determine the quality and shape of the created weld. These results are based on the orientation distance. and speed of the welding torch and depth of penetration. The welding process and resulting weld bc.1d are displayed in a virtual environment with screenplay interactive training modules. For review. weld quality and recorded process values can be displayed and diagnosed after welding. To help in the le.tming process, a

  7. Construção e aplicação de um minissensor de filme de bismuto utilizando materiais de baixo custo para determinações voltamétricas in loco

    Directory of Open Access Journals (Sweden)

    Luiz Carlos S. Figueiredo-Filho

    2012-01-01

    Full Text Available The construction of a low cost mini sensor containing a bismuth-film electrode (BiFE, as work electrode, a silver electrode as pseudo reference electrode, and copper as counter electrode is proposed. The application of this mini sensor using a low cost electrochemical cell for in loco voltammetric determinations of inorganic and organic analytes is also described.

  8. Isolated loco-regional recurrence of breast cancer is more common in young patients and following breast conserving therapy: Long-term results of European Organisation for Research and Treatment of Cancer studies

    NARCIS (Netherlands)

    de Bock, Truuske; van der Hage, J.A.; Putter, H.; Bonnema, J.; Bartelink, H.; van de Velde, C.J.

    2006-01-01

    The aim of this study was to evaluate prognostic factors for isolated loco-regional recurrence in patients treated for invasive stage I or H breast cancer. The study population comprised 3602 women who had undergone primary surgery for early stage breast cancer, who were enrolled in European Organis

  9. Linking white matter integrity loss to associated cortical regions using structural connectivity information in Alzheimer's disease and fronto-temporal dementia: the Loss in Connectivity (LoCo) score.

    Science.gov (United States)

    Kuceyeski, Amy; Zhang, Yu; Raj, Ashish

    2012-07-16

    It is well known that gray matter changes occur in neurodegenerative diseases like Alzheimer's (AD) and fronto-temporal dementia (FTD), and several studies have investigated their respective patterns of atrophy progression. Recent work, however, has revealed that diffusion MRI that is able to detect white matter integrity changes may be an earlier or more sensitive biomarker in both diseases. However, studies that examine white matter changes only are limited in that they do not provide the functional specificity of GM region-based analysis. In this study, we develop a new metric called the Loss in Connectivity (LoCo) score that gives the amount of structural network disruption incurred by a gray matter region for a particular pattern of white matter integrity loss. Leveraging the relative strengths of WM and GM markers, this metric links areas of WM integrity loss to their connected GM regions as a first step in understanding their functional implications. The LoCo score is calculated for three groups: 18AD, 18 FTD, and 19 age-matched normal controls. We show significant correlations of the LoCo with the respective atrophy patterns in AD (R=0.51, p=2.2 × 10(-9)) and FTD (R=0.49, p=2.5 × 10(-8)) for a standard 116 region gray matter atlas. In addition, we demonstrate that the LoCo outperforms a measure of gray matter atrophy when classifying individuals into AD, FTD, and normal groups.

  10. Isolated loco-regional recurrence of breast cancer is more common in young patients and following breast conserving therapy : Long-term results of European Organisation for Research and Treatment of Cancer studies

    NARCIS (Netherlands)

    de Bock, GH; van der Hage, JA; Putter, H; Bonnema, J; Bartelink, H; van de Velde, CJ

    2006-01-01

    The aim of this study was to evaluate prognostic factors for isolated loco-regional recurrence in patients treated for invasive stage I or H breast cancer. The study population comprised 3602 women who had undergone primary surgery for early stage breast cancer, who were enrolled in European Organis

  11. Role of tumour-free margin distance for loco-regional control in vulvar cancer-a subset analysis of the Arbeitsgemeinschaft Gynakologische Onkologie CaRE-1 multicenter study

    NARCIS (Netherlands)

    Woelber, Linn; Griebel, Lis-Femke; Eulenburg, Christine; Sehouli, Jalid; Jueckstock, Julia; Hilpert, Felix; de Gregorio, Nikolaus; Hasenburg, Annette; Ignatov, Atanas; Hillemanns, Peter; Fuerst, Sophie; Strauss, Hans-Georg; Baumann, Klaus H.; Thiel, Falk C.; Mustea, Alexander; Meier, Werner; Harter, Philipp; Wimberger, Pauline; Hanker, Lars Christian; Schmalfeldt, Barbara; Canzler, Ulrich; Fehm, Tanja; Luyten, Alexander; Hellriegel, Martin; Kosse, Jens; Heiss, Christoph; Hantschmann, Peer; Mallmann, Peter; Tanner, Berno; Pfisterer, Jacobus; Richter, Barbara; Neuser, Petra; Mahner, Sven

    2016-01-01

    Aim of the study: A tumour-free pathological resection margin of >= 8 mm is considered state-of-the-art. Available evidence is based on heterogeneous cohorts. This study was designed to clarify the relevance of the resection margin for loco-regional control in vulvar cancer. Methods: AGO-CaRE-1 is a

  12. Herança genética e desequilíbrio de ligação em locos de isoenzimas em Esenbeckia leiocarpa. Genetic inheritance and linkage disequilibrium in isozymes loci of Esenbeckia leiocarpa.

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Sícole SEOANE

    2004-06-01

    Full Text Available Oito sistemas enzimáticos (EST, IDH, PGM, PGI, MDH, PER, 6PGDH e SKDH codificando nove locos foram investigados em Esenbeckia leiocarpa. Quatro sistemas isoenzimáticos foram monomórficos (IDH, PGM, 6PGDH e SKDH e quatro polimórficos (EST, PGI, MDH e PER. A herança mendeliana foi confirmada para quatro locos, pelo teste de ajuste dos padrões de segregação observados em relação à razão de segregação esperada 1:1, em progênies de árvores heterozigotas. O desequilíbrio de ligação foi examinado para dez pares de locos. Apenas um simples par de locos parece estar em desequilíbrio de ligação, Est-1:Prx-1.Eight enzymes systems (EST, IDH, PGM, PGI, MDH, PER, 6PGDH and SKDH coding for nine loci were investigate in Esenbeckia leiocarpa. Four allozyme systems were monomorphic (IDH, PGM, 6PGDH and SKDH and four polymorphic (EST, PGI, MDH and PER. Mendelian inheritance was confirmed for four loci by testing the fit of band-pattern to 1:1 expected segregation ratio in progeny from heterozygous trees. Linkage disequilibrium was examined for ten pair of allozymes loci. A simple pair of loci appears to be in linkage disequilibrium, Est-1:Prx-1.

  13. Numerical Modeling and Simulation of the Movable Contact Tool-Workpiece and Application in Technological Processes

    Directory of Open Access Journals (Sweden)

    Leon Kukielka

    2010-06-01

    Full Text Available Grinding, embossing, burnishing, thread rolling, drawing, cutting, turning are very complicated technological processes. To increase the quality of the product and minimize the cost of process, we should know the physical phenomena which exist during the process. The phenomena on a typical incremental step were described using a step-by-step incremental procedure, with an updated Lagrange's formulation. The technological processes are considered as geometrical and physical non-linear initial and boundary problems. The finite element method (FEM and the dynamic explicit method (DEM were used to obtain the solution. The application was developed in the ANSYS/LS-DYNA system, which makes possible a complex time analysis of the physical phenomena: states of displacements, strains and stresses. Numerical computations of the strain and stress have been conducted with the use of methodology which requires a proper definition of the contact zone, without the necessity to introduce boundary conditions. Examples of calculations are presented.

  14. Theoretical approaches to creation of robotic coal mines based on the synthesis of simulation technologies

    Science.gov (United States)

    Fryanov, V. N.; Pavlova, L. D.; Temlyantsev, M. V.

    2017-09-01

    Methodological approaches to theoretical substantiation of the structure and parameters of robotic coal mines are outlined. The results of mathematical and numerical modeling revealed the features of manifestation of geomechanical and gas dynamic processes in the conditions of robotic mines. Technological solutions for the design and manufacture of technical means for robotic mine are adopted using the method of economic and mathematical modeling and in accordance with the current regulatory documents. For a comparative performance evaluation of technological schemes of traditional and robotic mines, methods of cognitive modeling and matrix search for subsystem elements in the synthesis of a complex geotechnological system are applied. It is substantiated that the process of technical re-equipment of a traditional mine with a phased transition to a robotic mine will reduce unit costs by almost 1.5 times with a significant social effect due to a reduction in the number of personnel engaged in hazardous work.

  15. Digital scene simulation: the synergy of computer technology and human creativity

    Energy Technology Data Exchange (ETDEWEB)

    Demos, G.; Brown, M.D.; Weinberg, R.A.

    1984-01-01

    The computer graphics capabilities at Digital Productions, based on a Cray X-MP supercomputer for computer-created imagery, are presented. The authors describe the hardware, software for image rendering and simulation and the use of these by artists. The computing requirements for high-resolution graphics are given. Particular emphasis is placed on the system's ease of use and speed compared to traditional animation techniques. The direction of current research is summarized. 38 references.

  16. Thermal Characterization of the Air Force Institute of Technology Solar Simulation Thermal Vacuum Chamber

    Science.gov (United States)

    2014-03-27

    Decrease KI Decrease Increase Increase Eliminate KD Small Change Decrease Decrease No Change A general process for manually tuning a PID ...solar simulator if restrictions were required. PID Coefficient Tuning Again, due to lack of previous testing of the chamber, the PID coefficients set...prescribed < 0.1°C bound. PID coefficient tuning was done throughout the process of testing in order to get as close to desired performance, with small

  17. Implementation of numerical simulation techniques in analysis of the accidents in complex technological systems

    Energy Technology Data Exchange (ETDEWEB)

    Klishin, G.S.; Seleznev, V.E.; Aleoshin, V.V. [RFNC-VNIIEF (Russian Federation)

    1997-12-31

    Gas industry enterprises such as main pipelines, compressor gas transfer stations, gas extracting complexes belong to the energy intensive industry. Accidents there can result into the catastrophes and great social, environmental and economic losses. Annually, according to the official data several dozens of large accidents take place at the pipes in the USA and Russia. That is why prevention of the accidents, analysis of the mechanisms of their development and prediction of their possible consequences are acute and important tasks nowadays. The accidents reasons are usually of a complicated character and can be presented as a complex combination of natural, technical and human factors. Mathematical and computer simulations are safe, rather effective and comparatively inexpensive methods of the accident analysis. It makes it possible to analyze different mechanisms of a failure occurrence and development, to assess its consequences and give recommendations to prevent it. Besides investigation of the failure cases, numerical simulation techniques play an important role in the treatment of the diagnostics results of the objects and in further construction of mathematical prognostic simulations of the object behavior in the period of time between two inspections. While solving diagnostics tasks and in the analysis of the failure cases, the techniques of theoretical mechanics, of qualitative theory of different equations, of mechanics of a continuous medium, of chemical macro-kinetics and optimizing techniques are implemented in the Conversion Design Bureau {number_sign}5 (DB{number_sign}5). Both universal and special numerical techniques and software (SW) are being developed in DB{number_sign}5 for solution of such tasks. Almost all of them are calibrated on the calculations of the simulated and full-scale experiments performed at the VNIIEF and MINATOM testing sites. It is worth noting that in the long years of work there has been established a fruitful and effective

  18. Design and Simulation of a New Optimized Full-Adder Using Carbon Nano Tube Technology

    Directory of Open Access Journals (Sweden)

    Abbas Asadi Aghbolaghi

    2015-07-01

    Full Text Available The full adder circuit is one of the most significant and prominent fundamental parts in digital processors and integrated circuits since it can be used for implementing all four basic computational functions including: addition, subtraction, multiplication, and division. so, in this paper a new low power and high performance full adder cell has been proposed with the benefit of using carbon nano tube field effect transistors. The proposed design contains 12 CNTFET transistors which are connected in pass transistor logic style to make the desired functionality. Carbon Nano Tube Field Effect Transistor (CNTFET has modified electrical characteristics such as low power consumption and high speed in comparison with MOSFET transistor; The proposed design is simulated using Hspice software based on CNTFET model and 0.65V supply voltage. the simulations are done considering three different frequencies, and three different load capacitors. The simulation results, which demonstrated in tables and diagrams, proved the superiority of proposed design in terms of power consumption and performance (PDP compared to the existing counterparts.

  19. Technology

    Directory of Open Access Journals (Sweden)

    Xu Jing

    2016-01-01

    Full Text Available The traditional answer card reading method using OMR (Optical Mark Reader, most commonly, OMR special card special use, less versatile, high cost, aiming at the existing problems proposed a method based on pattern recognition of the answer card identification method. Using the method based on Line Segment Detector to detect the tilt of the image, the existence of tilt image rotation correction, and eventually achieve positioning and detection of answers to the answer sheet .Pattern recognition technology for automatic reading, high accuracy, detect faster

  20. Using a computer-based simulation with an artificial intelligence component and discovery learning to formulate training needs for a new technology

    Energy Technology Data Exchange (ETDEWEB)

    Hillis, D.R.

    1992-01-01

    A computer-based simulation with an artificial intelligence component and discovery learning was investigated as a method to formulate training needs for new or unfamiliar technologies. Specifically, the study examined if this simulation method would provide for the recognition of applications and knowledge/skills which would be the basis for establishing training needs. The study also examined the effect of field-dependence/independence on recognition of applications and knowledge/skills. A pretest-posttest control group experimental design involving fifty-eight college students from an industrial technology program was used. The study concluded that the simulation was effective in developing recognition of applications and the knowledge/skills for a new or unfamiliar technology. And, the simulation's effectiveness for providing this recognition was not limited by an individual's field-dependence/independence.

  1. "In Loco Parentis" Revisited?

    Science.gov (United States)

    Murphree, Carolyn T.

    1986-01-01

    Suggests that many students are not aware of proper etiquette and proposes that business communication instructors offer a short bibliography and a few tips that can help students acquire more polish. (DF)

  2. Bandwidth-limited active suspension controller for an off-road vehicle based on co-simulation technology

    Institute of Scientific and Technical Information of China (English)

    Jinzhi FENG; Songlin ZHENG; Fan YU

    2008-01-01

    This paper presents the design process of a controller for bandwidth-limited active hydro-pneumatic suspension employed by an off-road vehicle based on co-simulation technology. First, a detailed multi-body dynamic model of the vehicle is established by using the ADAMS/View software package, which is followed by validation using a vehicle field test. Second, a combined PID and fuzzy controller is designed for the bandwidth-limited active suspension system and then programmed by means of S-functions in Matlab/Simulink, to which a data exchange interface with ADAMS/View is also defined. Third, the proposed control algorithm is implemented on the multi-body dynamic vehicle model to enable the co-simulation to run repeatedly until a more practical controller is achieved. In the end, the proposed active suspension system is compared with a conven-tional passive system. Simulation results show that the proposed active suspension system considerably improves both the ride and handling performance of the vehicle and therefore increases the maximum travel-ing speeds even on rough roads.

  3. NASA Center for Climate Simulation (NCCS) Advanced Technology AT5 Virtualized Infiniband Report

    Science.gov (United States)

    Thompson, John H.; Bledsoe, Benjamin C.; Wagner, Mark; Shakshober, John; Fromkin, Russ

    2013-01-01

    The NCCS is part of the Computational and Information Sciences and Technology Office (CISTO) of Goddard Space Flight Center's (GSFC) Sciences and Exploration Directorate. The NCCS's mission is to enable scientists to increase their understanding of the Earth, the solar system, and the universe by supplying state-of-the-art high performance computing (HPC) solutions. To accomplish this mission, the NCCS (https://www.nccs.nasa.gov) provides high performance compute engines, mass storage, and network solutions to meet the specialized needs of the Earth and space science user communities

  4. A New Strategy for Leveraging Current and Future Simulation Technologies for the U.S. Army

    Science.gov (United States)

    2007-11-02

    reference of future combat described in Orson Scott Card’s Ender’s Game inspired the author in this effort). 8 Don Wells, “Extreme Programming: A Gentle...trial and error), let’s do it! WORD COUNT = 8004. 21 ENDNOTES 1 Scott Nance, “Conference Demonstrates Growing Demand For Modeling and Simulation,” New...Model Design—A Better Way to Develop Embedded Control Systems”, 2002 SIMTECH Proceedings. Melbourne, Australia, 2002. Harmon, Scott . “Just Words

  5. Simulation of Digital Control Computer of Nuclear Power Plant Based on Virtual Machine Technology

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Xue Yan; Li, Shu; Li, Qing [China Nuclear Power Operation Technology Co., Wuhan (China)

    2011-08-15

    Based on analyzing DCC (Digital Control Computer) instruction sets, memory map, display controllers and I/O system, virtual machine of DCC (abbr. VM DCC) has been developed. The executive and control programs, same as running on NPP (Nuclear Power Plant) unit's DCC, can run on the VM DCC smoothly and get same control results. Dual VM DCC system has been successfully applied in NPP FSS(Full Scope Simulator) training. It not only improves FSS's fidelity but also makes maintaining easier.

  6. Outcomes of loco-regional therapy for down-staging of hepatocellular carcinoma prior to liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Xian-Jie Shi; Xin Jin; Mao-Qiang Wang; Li-Xin Wei; Hui-Yi Ye; Yu-Rong Liang; Ying Luo; Jia-Hong Dong

    2011-01-01

    BACKGROUND: The  number  of  loco-regional  therapies (LRTs)  for  hepatocellular  carcinoma  (HCC)  has  increased dramatically  during  the  past  decade.  Many  patients  with HCC  who  were  beyond  the  Milan  criteria  were  allowed to  receive  a  liver  transplantation  (LT)  once  the  HCC  was successfully  down-staged.  This  retrospective  study  aimed to analyze the outcomes of LRTs prior to LT in patients with HCC beyond the Milan criteria. METHODS: We analyzed 56 patients treated from June 2006 to  March  2010:  22  met  the  Milan  criteria  (T1+T2,  39.3%), 16 had T3 tumors (28.6%), and 11 had T4a tumors (19.6%), while  7  were  suspected  of  tumor  vascular  invasion  (T4b, 12.5%). All patients underwent preoperative LRTs, including transcatheter  arterial  chemoembolization,  radiofrequency ablation,  percutaneous  ethanol  injection,  liver  resection, and/or  microwave  coagulation  therapy.  The  number  of  the patients  who  were  successfully  down-staged  before  LT,  the types  of  LRTs  used  before  LT,  and  their  outcomes  after  LT were recorded. RESULTS: Eleven  patients  had  necrotic  tumors  (pT0,  19.6%); 6 had pT1 tumors (10.7%), 22 had pT2 tumors (39.3%), 6 had pT3 tumors (10.7%), 5 had pT4a tumors (8.9%), and 6 had pT4b tumors  (10.7%).  The  histopathologic  tumors  of  39  patients (69.6%)  were  down-staged  and  met  the  established  Milan criteria  (pT0-2).  Imaging-proven  under-staging  was  present in  5  HCC  patients  (8.9%)  who  had  tumors  involving  the

  7. Data collection in a live mass casualty incident simulation: automated RFID technology versus manually recorded system.

    Science.gov (United States)

    Ingrassia, Pier Luigi; Carenzo, Luca; Barra, Federico Lorenzo; Colombo, Davide; Ragazzoni, Luca; Tengattini, Marco; Prato, Federico; Geddo, Alessandro; Della Corte, Francesco

    2012-02-01

    To demonstrate the applicability and the reliability of a radio frequency identification (RFID) system to collect data during a live exercise. A rooftop collapse of a crowded building was simulated. Fifty-three volunteers were trained to perform as smart victims, simulating clinical conditions, using dynamic data cards, and capturing delay times and triage codes. Every victim was also equipped with a RFID tag. RFID antenna was placed at the entrance of the advanced medical post (AMP) and emergency department (ED) and recorded casualties entering the hospital. A total of 12 victims entered AMP and 31 victims were directly transferred to the ED. 100% (12 of 12 and 31 of 31) of the time cards reported a manually written hospital admission time. No failures occurred in tag reading or data transfers. A correlation analysis was performed between the two methods plotting the paired RFID and manual times and resulted in a r=0.977 for the AMP and r=0.986 for the ED with a P value of less than 0.001. We confirmed the applicability of RFID system to the collection of time delays. Its use should be investigated in every aspect of data collection (triage, treatments) during a disaster exercise.

  8. Simulative technology for auxiliary fuel tank separation in a wind tunnel

    Institute of Scientific and Technical Information of China (English)

    Ma Xin; Liu Wei; Chen Ling; Li Xiao; Jia Zhenyuan; Shang Zhiliang

    2016-01-01

    In this paper, we propose a simulative experimental system in wind tunnel conditions for the separation of auxiliary fuel tanks from an aircraft. The experimental system consists of a simulative release mechanism, a scaled model and a pose measuring system. A new release mechanism was designed to ensure stability of the separation. Scaled models of the auxiliary fuel tank were designed and their moment of inertia was adjusted by installing counterweights inside the model. Pose param-eters of the scaled model were measured and calculated by a binocular vision system. Additionally, in order to achieve high brightness and high signal-to-noise ratio of the images in the dark enclosed wind tunnel, a new high-speed image acquisition method based on miniature self-emitting units was pre-sented. Accuracy of the pose measurement system and repeatability of the separation mechanism were verified in the laboratory. Results show that the position precision of the pose measurement system can reach 0.1 mm, the precision of the pitch and yaw angles is less than 0.1? and that of the roll angle can be up to 0.3?. Besides, repeatability errors of models’ velocity and angular velocity controlled by the release mechanism remain small, satisfying the measurement requirements. Finally, experiments for the separation of auxiliary fuel tanks were conducted in the laboratory.

  9. 局部复发性鼻咽癌的临床病理学特征%Pathological characteristics of loco-regional recurrent nasopharyngeal carcinoma

    Institute of Scientific and Technical Information of China (English)

    雍娟娟; 吴秋良; 宗永生; 侯景辉; 梁建中; 匡亚玲; 奚少彦; 卢佳斌

    2014-01-01

    Purpose To investigate the pathological characteristics of loco-regional recurrent nasopharyngeal carcinoma ( rNPC ) . Methods Nasopharyngeal biopsy specimens of 46 rNPCs and 63 primary NPCs were collected. HE staining, immunohistochemistry and EBV small RNAs ( EBERs) in-situ hybridization were performed. Results The over-expression rates of both p63 and CK5/6 in rNPC were significantly higher than those of primary NPCs (P=0. 005, P=0. 026), while no statistical significance of Ki-67 over-ex-pression existed between the two groups ( P=0. 387 ) . More necrotic tissues, inflammatory exudates, giant bizarre carcinoma cells, desmoplastic stroma, giant bizarre tumor cells and higher degree of squamous differentiation were found in rNPCs. The carcinoma cells of 5 rNPCs were negative for both EBERs in-situ hybridization and LMP-1 immunohistochemical staining. Conclusion The loco-re-gional rNPC has two peaks of latency interval:2~5 and 9~11 years. The loco-regional rNPC cells have higher degree of squamous differentiation with higher expression of p63 and CK5/6, as well as more invasive ability. In addition, both EBERs in-situ hybridization and LMP-1 immunostaining are negative in 10. 87% (5/46) of loco-regional rNPC.%目的:探讨局部复发性鼻咽癌的临床病理学特征。方法收集46例局部复发性鼻咽癌和63例原发性鼻咽癌活检组织,行HE染色、免疫组化、EBERs原位杂交检测。结果局部复发性鼻咽癌中p63和CK5/6的强阳性表达率均高于原发性鼻咽癌(P=0.005和P=0.026);Ki-67的强阳性表达率差异无显著性(P=0.387);组织坏死、炎性渗出和间质促纤维增生明显;畸形瘤巨细胞多见,癌细胞鳞状分化程度更高。5例复发性鼻咽癌细胞EBERs原位杂交和LMP-1免疫组化标记均为阴性。结论(1)局部复发性鼻咽癌有2个复发间歇高峰,即2~5年和9~11年。(2)局部复发性鼻咽癌细胞p63和CK5/6强阳性表达率、鳞状分化程度更高

  10. Simulation of Resource Usage in Parallel Evolutionary Peptide Optimization using JavaSpaces Technology

    CERN Document Server

    Wira-Alam, Andias

    2009-01-01

    Peptide Optimization is a highly complex problem and it takes very long time of computation. This optimization process uses many software applications in a cluster running GNU/Linux Operating System that perform special tasks. The application to organize the whole optimization process had been already developed, namely SEPP (System for Evolutionary Pareto Optimization of Peptides/Polymers). A single peptide optimization takes a lot of computation time to produce a certain number of individuals. However, it can be accelerated by increasing the degree of parallelism as well as the number of nodes (processors) in the cluster. In this master thesis, I build a model simulating the interplay of the programs so that the usage of each resource (processor) can be determined and also the approximated time needed for the overall optimization process. There are two Evolutionary Algorithms that could be used in the optimization, namely Generation-based and Steady-state Evolutionary Algorithm. The results of each Evolution...

  11. Physical Simulation of New Desulphurization Technology Using Pulsed and Rotary Stirring-Injection

    Institute of Scientific and Technical Information of China (English)

    WU Wei; HU Yan-bin; LIU Liu; DING Yong-liang

    2008-01-01

    The contrast experiment of different stirring modes, which includes a new type of stirring-injection with the method of pulse and rotation, and the initial one-way stirring method, is done through physical simulation in the laboratory. The stirring methods of pulse and rotation are of two kinds. One is pulsed and rotary stirrer with positive and opposite directions. The other is pulsed and rotary stirrer with rotation-stop-rotation. The results show that the stirring mode of pulse and rotation has better effects than the one-way stirring method. The specific effects are that the mixing time of the melting bath is apparently shortened, the number of grains involved in the liquid surface is increased, and the residence time of air bubble in water is doubled.

  12. The current status of the development of the technology on 3D computer simulation in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hee Reyoung; Park, Seung Kook; Chung, Un Soo; Jung, Ki Jung

    2002-05-01

    The development background and property of the COSIDA, which is the 3D computer simulation system for the analysis on the dismantling procedure of the nuclear facilities in Japan was reviewed. The function of the visualization on the work area, Kinematics analysis and dismantling scenario analysis, which are the sub systems of the COSIDA, has been investigated. The physical, geometrical and radiological properties were modelled in 2D or 3D in the sub system of the visualization of the work area. In the sub system of the kinematics analysis, the command set on the basic work procedure for the control of the motion of the models at a cyber space was driven. The suitability of the command set was estimated by the application of COSIDA to the programming on the motion of the remote dismantling tools for dismantling the components of the nuclear facilities at cyber space.

  13. Simulation and modal analysis of the uplift device of a sugarcane harvester using virtual prototype technology

    Institute of Scientific and Technical Information of China (English)

    HU Ying-chun; LI Shang-ping

    2007-01-01

    A three-dimensional model of the uplift device of a sugarcane harvester was built up in Pro/Engineer. Simulation and evaluation of its motional and dynamic performance were performed with the automatic dynamic analysis of mechanical system (ADAMS). ANSYS program was applied to the structural analysis of the model. A finite element analytic model was built up with the bottom-up methodology and was meshed. The default Block Lanczos method was used to work out the native frequency. The results indicate that the five lower modes-the transpotaion wheel, the left holding device, the right holding device, the left cutter disk, and the right cutter disk- and displacement of vibratory type only slightly affect the process of sugarcane harvester and harvesting quality. So it is advisable that the optimization of the static intensity other than the dynamic stiffness of uplift device be executed.

  14. Theoretical aspects of non-newtonian fluids flow simulation in food technologies

    Directory of Open Access Journals (Sweden)

    E. Biletskii

    2015-05-01

    Full Text Available Introduction. The problems of simulating viscoplastic longitudinal and cross-sectional flow of non-Newtonian fluids are overviewed. Materials and methods. For the first time the superposition method by expressing the components of the stress tensor for building flow fields with higher dimension from flow fields with lower dimension with various boundary conditions when rheological parameters change depending on pressure was used. The flows in the channel are categorized by velocity and pressure values in each point of the section. Results.The theoretical methods for simulating flows of non-Newtonian fluids in channels of different geometry with moving bounds and pressure drop on channel edges with respect to functional connections between main process parameters are described using the superposition method. It is shown that longitudinal and cross-sectional are reduced to the collection of one-dimensional longitudinal flows of the same type which allow to describe three-dimensional isothermal in rectangular channel and two-dimensional flows in flat channels with different channel aspect ratio. The received theoretical two- and three-dimensional model of viscous flows in channels with basic geometry allow to research main regularities of the process and to establish optimal macro-kinetic and macro-dynamic flow characteristics of non-Newtonian materials which are aimed at reducing energy costs and material consumption of food processing equipment. Conclusion.The developed and theoretically reasonable three-dimensional models flows of non-Newtonian fluids in channels allow to perform qualitatively new design of food processing equipment which allows to reduce energy costs and material consumption.

  15. Multi-modality management for loco-regionally advanced laryngeal and hypopharyngeal cancer: balancing the benefit of efficacy and functional preservation.

    Science.gov (United States)

    Qian, Wei; Zhu, Guopei; Wang, Yulong; Wang, Xiaoshen; Ji, Qinghai; Wang, Yu; Dou, Shengjin

    2014-09-01

    The 5-year overall survival (OS) of loco-regionally advanced laryngeal and hypopharyngeal carcinoma (LA-LHC) has declined over the past two decades following the wide application of non-surgical approaches. We aimed to define the new role of open surgery combined with adjuvant chemoradiotherapy in the treatment of LA-LHC for improving survival while maintaining a functional larynx. In the current study, 90 LA-LHC patients treated with open surgery followed by postoperative RT/CRT in our institute from May 2005 to December 2012 were retrospectively analyzed. OS, disease-free survival (DFS), loco-regional failure-free survival (LRFFS) and distant metastasis-free survival (DMFS) were calculated, and prognostic factors were analyzed. Functional larynx preservation results were evaluated according to the head and neck quality of life (QoL) Scale. With a median follow-up period of 37 months, the 3- and 5-year OS, DFS, LRFFS and DMFS were 71.3, 63.7, 85.9, 73.7 and 55.9, 53.0, 81.6, 71.9 %, respectively. Vascular embolism and extracapsular extension (ECE) of the lymph nodes were prognostic factors for poorer OS (p = 0.045 and 0.046, respectively). Vascular embolism was the only prognostic factor for poorer DMFS (p = 0.005). Patients who underwent a conservative partial laryngectomy (CPL) experienced a higher QoL in the domains of speech, swallowing and emotion. Functional larynx preservation was achieved in 36/45 patients (80 %) who received CPL. The results of our study demonstrated that CPL followed by adequate adjuvant therapy could achieve superior oncological results compared with non-surgical approaches in LA-LHC patients while also maintaining satisfactory functional larynx in a majority of patients.

  16. Positive versus negative sentinel nodes in early breast cancer patients: axillary or loco-regional relapse and survival. A study spanning 2000-2012.

    Science.gov (United States)

    García Fernández, A; Chabrera, C; García Font, M; Fraile, M; Lain, J M; Barco, I; González, C; Gónzalez, S; Reñe, A; Veloso, E; Cassadó, J; Pessarrodona, A; Giménez, N

    2013-10-01

    Sentinel Node Biopsy (SNB) is a minimally invasive alternative to elective axillary lymph node dissection (ALND) for nodal staging in early breast cancer. The present study was conducted to evaluate prognostic implications of a negative sentinel node (SN) versus a positive SN (followed by completion ALND) in a closely followed-up sample of early breast cancer patients. We studied 889 consecutive breast cancer patients operated for 908 primaries. Patients received adjuvant therapy with chemotherapy, hormone therapy and eventually trastuzumab. Radiation therapy was based on tangential radiation fields that usually included axillary level I. Median follow-up was 47 months. Axillary recurrence was seen in 1.2% (2/162) of positive SN patients, and 0.8% (5/625) of negative SN patients (p = n.s.). There was an overall 3.2% loco-regional failure rate (29/908). Incidence of distant recurrence was 3.3% (23/693) for negative SN patients, and 4.6% (9/196) for positive SN patients (p = n.s.). Overall mortality rate was 4% (8/198) for positive SN patients, while the corresponding specific mortality rate was 2.5% (5/198). For patients with negative SNs, overall mortality was 4.9% (34/693), and the specific mortality was 1.4% (19/693) (p = n.s.). We did not find significant differences in axillary/loco-regional relapse, distant metastases, disease-free interval or mortality between SN negative and SN positive patients, with a follow-up over 4 years. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Alternative decision modelling techniques for the evaluation of health care technologies: Markov processes versus discrete event simulation.

    Science.gov (United States)

    Karnon, Jonathan

    2003-10-01

    Markov models have traditionally been used to evaluate the cost-effectiveness of competing health care technologies that require the description of patient pathways over extended time horizons. Discrete event simulation (DES) is a more flexible, but more complicated decision modelling technique, that can also be used to model extended time horizons. Through the application of a Markov process and a DES model to an economic evaluation comparing alternative adjuvant therapies for early breast cancer, this paper compares the respective processes and outputs of these alternative modelling techniques. DES displays increased flexibility in two broad areas, though the outputs from the two modelling techniques were similar. These results indicate that the use of DES may be beneficial only when the available data demonstrates particular characteristics.

  18. Neutronic simulation calculations to assess the proliferation resistance of nuclear technologies; Neutronenphysikalische Simulationsrechnungen zur Proliferationsresistenz nuklearer Technologien

    Energy Technology Data Exchange (ETDEWEB)

    Englert, Matthias

    2009-07-13

    This thesis investigates the proliferation resistance of nuclear technologies on the basis of three case studies. After a brief description of the concept of proliferation resistance the utilized computer codes and methods are presented. The first case study investigates the potential of monolithic fuel for the conversion of one-fuel-element high-flux research reactors from highly enriched to low enriched uranium using the example of the german research reactor FRM-II. The second case study assesses the proliferation potential of future tokamak based fusion reactors by using neutronic simulations of a possible plutonium production. The third example investigates the proliferation potential of spallation neutron sources to produce nuclear weapon relevant material and the proliferation resistance of such facilities. (orig.)

  19. Application and Development of Simulation Technology in Cold Continuous Rolling Mill%仿真技术在冷连轧系统的应用及发展

    Institute of Scientific and Technical Information of China (English)

    崔建江; 吴胜昔; 袁枫华; 徐心和

    2001-01-01

    This paper analyses a dynamic simulation system of cold rolling mill and discusses the status and signification of simulation application and development of cold rolling mill in our country and foreign countries. Modeling and process of simulation in cold rolling mill are analysed. The execution of dynamic simulation includes the advanced modelling technology and time coordination scheduling and the use of multi-advanced simulation technology, such as coordernation simulation, simulation database, and integrated simulation. In this field virtual reality and intelligent simulation maybe act as future development in the end.%分析了一类冷连轧动态仿真系统,综述了仿真技术在冷连轧中在国内外的应用发展现状、以及发展冷连轧动态系统的意义。分析了仿真动态系统的建模及实现过程,冷连轧动态仿真的实施包含先进的模型化技术及时间协调调度,多种先进仿真技术的使用如协调仿真、仿真数据库技术一体化仿真。最后展望了该领域在虚拟现实和智能仿真技术的今后发展方向。

  20. Android应用模拟交互技术的研究%Research on Android Application Simulation Interactive Technology

    Institute of Scientific and Technical Information of China (English)

    邹加磊; 洪亮; 杨鸣坤

    2014-01-01

    Large amount of data is needed by the Android malware detection technology based on behavior analysis. A way of data collec-tion based on the technology of user simulation interaction is proposed. Using a computer server and several Android devices,can auto-matically collect useful data for analysis and reduce the work of human involvement. By combing the designed simulation strategy which includes environment,time,events difference and testing tools,the system can automatically accomplish application automatic installation, interaction running,data collection and automatic uninstallation. Experimental results show that the proposed solution architecture is feasi-ble,which can effectively collect the data of program.%针对于行为分析的Android恶意代码检测技术均需要收集大量的运行数据,文中提出了一种基于用户模拟交互技术的数据收集方式。使用计算机及若干个Android设备,自动化完成有效分析数据的收集,减少了人工参与的程度。通过结合使用制定的Android应用程序的运行策略,包括环境差异策略、时间差异策略、事件差异策略,以及测试工具等,完成应用程序在Android设备上的自动安装、交互运行、数据收集以及自动卸载。验证实验表明,该用户模拟交互技术能有效收集应用程序的运行数据,是一种可行的应用方案。

  1. Simulation-Based e-Learning Tools for Science,Engineering, and Technology Education(SimBeLT)

    Science.gov (United States)

    Davis, Doyle V.; Cherner, Y.

    2006-12-01

    The focus of Project SimBeLT is the research, development, testing, and dissemination of a new type of simulation-based integrated e-learning set of modules for two-year college technical and engineering curricula in the areas of thermodynamics, fluid physics, and fiber optics that can also be used in secondary schools and four-year colleges. A collection of sophisticated virtual labs is the core component of the SimBeLT modules. These labs will be designed to enhance the understanding of technical concepts and underlying fundamental principles of these topics, as well as to master certain performance based skills online. SimBeLT software will help educators to meet the National Science Education Standard that "learning science and technology is something that students do, not something that is done to them". A major component of Project SimBeLT is the development of multi-layered technology-oriented virtual labs that realistically mimic workplace-like environments. Dynamic data exchange between simulations will be implemented and links with instant instructional messages and data handling tools will be realized. A second important goal of Project SimBeLT labs is to bridge technical skills and scientific knowledge by enhancing the teaching and learning of specific scientific or engineering subjects. SimBeLT builds upon research and outcomes of interactive teaching strategies and tools developed through prior NSF funding (http://webphysics.nhctc.edu/compact/index.html) (Project SimBeLT is partially supported by a grant from the National Science Foundation DUE-0603277)

  2. Actual principles of the simulation of state-of-the-art technologies of laser processing of materials

    Science.gov (United States)

    Kovalev, Oleg B.

    2011-02-01

    Here we present the results of mathematical, numerical, and experimental simulation of the processes of interaction between the laser radiation and metals in the technologies of gas-laser cutting of thick-sheet materials and laser gas-powder cladding at the production of coatings and 3D objects by the DMD (Direct Material Deposition) method. The peculiarities of jet 3D flows of the working gases in narrow channels, geometrically identical to keyholes, are studied. It is demonstrated that during the stainless steel cutting, supersonic gas flows form local regions of separation flows which in turn result in the worse carry-away of the metal by the gas flow; these factors increase the roughness (striation) and worsen the surface quality. A vortex flow was found inside the cut at the subsonic jet flows typical for the oxygen gas-laser cutting of low-carbon steel; this flow causes slagging of the cut bottom edge. The processes running inside the laser cut at the fusible metals cutting with the low-power radiation were visualized under the laboratory conditions. Some new concepts of the processes running inside the keyhole have been gained; we also propose the explanations of the mechanisms of striation and other surface defects formation during the cutting of thick-sheet standard metals on the automate laser technological complex. A mathematical model of the volumetric laser-powder cladding is proposed. The submitted results concern the numerical simulation of multi-layer flows of shaping and carrier gases with the gas-jet transportation of powder particles into the laser spot on the substrate.

  3. Flutter Analysis of a Morphing Wing Technology Demonstrator: Numerical Simulation and Wind Tunnel Testing

    Directory of Open Access Journals (Sweden)

    Andreea KOREANSCHI

    2016-03-01

    Full Text Available As part of a morphing wing technology project, the flutter analysis of two finite element models and the experimental results of a morphing wing demonstrator equipped with aileron are presented. The finite element models are representing a wing section situated at the tip of the wing; the first model corresponds to a traditional aluminium upper surface skin of constant thickness and the second model corresponds to a composite optimized upper surface skin for morphing capabilities. The two models were analyzed for flutter occurrence and effects on the aeroelastic behaviour of the wing were studied by replacing the aluminium upper surface skin of the wing with a specially developed composite version. The morphing wing model with composite upper surface was manufactured and fitted with three accelerometers to record the amplitudes and frequencies during tests at the subsonic wind tunnel facility at the National Research Council. The results presented showed that no aeroelastic phenomenon occurred at the speeds, angles of attack and aileron deflections studied in the wind tunnel and confirmed the prediction of the flutter analysis on the frequencies and modal displacements.

  4. Use of Web 2.0 Technologies for Public Outreach on a Simulated Mars Mission

    Science.gov (United States)

    Ferrone, Kristine; Shiro, Brian; Palaia, Joseph E., IV

    2009-01-01

    Recent advances in social media and internet communications have revolutionized the ways people interact and disseminate information. Astronauts are already taking advantage of these tools by blogging and tweeting from space, and almost all NASA missions now have presences on the major social networking sites. One priotity for future human explorers on Mars will be communicating their experiences to the people back on Earth. During July 2009, a 6-member crew of volunteers carried out a simulated Mars mission at the Flashline Mars Arctic Research Station (FMARS). The Mars Society built the mock Mars habitat in 2000-01 to help develop key knowledge and inspire the public for human Mars exploration. It is located on Devon island about 1600 km from the North Pole within the Arctic Circle. The structure is situated on the rim of Haughton Crater in an environment geologically and biologically analogous to Mars. Living in a habitat, conducting EVAs wearing spacesuits, and observing communication delays with "Earth,"the crew endured restrictions similar to those that will be faced by future human Mars explorers. Throughout the expedition, crewmembers posted daily blog entries, reports, photos, videos, and updates to their website and social media outlets Twitter, Facebook, YouTube, and Picasa Web Albums. During the sixteen EVAs of thier field science research campaign, FMARS crewmembers collected GPS track information and took geotagged photos using GPS-enabled cameras. They combined their traverse GPS tracks with photo location information into KML/KMZ files that website visitors can view in Google Earth.

  5. Simulation about hot stamping of ultra-high strength steel on the basis of lightweight technology

    Institute of Scientific and Technical Information of China (English)

    Liu Qiang; Ma Fangwu; Wang Xiaona; Yao Zaiqi; Song Wei; Zhao Fuquan; Ma Mingttu; Song Leifeng

    2012-01-01

    With the development of automobile lightweight, it is very necessary to apply the ultra-high strength steel parts manufactured by hot stamping, which offers the possibility to reduce the weight of automobiles and maintain the safety requirement. In order to complete hot stamping, it is important to design the structure of parts reasonably, which is related with reasonable matching of strength. The objective of this paper is to guide the design of parts manufactured by hot stamping and find the forming technical requirements of vehicle performance. Through experiments, the paper obtains the stress and strain curves at different deformation temperatures and strain rates. Based on experimental data, the constitutive relationship model is established which can reflect the deformation capacity of ultra-high strength steel during the process of hot stamping. Combined with finite element simulation results of hot stamping by commercial soft- ware AUTOFORM, transfer path of load and matching law of strength, the paper determines the design criteria and forming technical requirements of parts manufactured by hot stamping. At the same time, the impact performance of front cross member internal plate is taken into consideration.

  6. Zonal extraction technology and numerical simulation analysis in open pit coal mine

    Institute of Scientific and Technical Information of China (English)

    Chen Yanlong; Cai Qingxiang; Shang Tao; Peng Hongge; Zhou Wei; Chen Shuzhao

    2012-01-01

    In order to enhance coal recovery ratio of open pit coal mines,a new extraction method called zonal mining system for residual coal around the end-walls is presented.The mining system can improve economic benefits by exploiting haulage and ventilation roadways from the exposed position of coal seams by utilizing the existing transportation systems.Moreover,the main mining parameters have also been discussed.The outcome shows that the load on coal seam roof is about 0.307 MPa and the drop step of the coal seam roof about 20.3 m when the thickness of cover and average volume weight are about 120 m and 0.023 MN/m3 respectively.With the increase of mining height and width,the coal recovery ratio can be improved.However,when recovery ratio is more than 0.85,the average stress on the coal pillar will increase tempestuously,so the recovery ratio should also be controlled to make the coal seam roof safe.Based on the numerical simulation results,it is concluded that the ratio of coal pillar width to height should be more than 1.0 to make sure the coal pillars are steady,and there are only minor displacements on the end-walls.

  7. Commnity Petascale Project for Accelerator Science And Simulation: Advancing Computational Science for Future Accelerators And Accelerator Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Spentzouris, Panagiotis; /Fermilab; Cary, John; /Tech-X, Boulder; Mcinnes, Lois Curfman; /Argonne; Mori, Warren; /UCLA; Ng, Cho; /SLAC; Ng, Esmond; Ryne, Robert; /LBL, Berkeley

    2011-10-21

    The design and performance optimization of particle accelerators are essential for the success of the DOE scientific program in the next decade. Particle accelerators are very complex systems whose accurate description involves a large number of degrees of freedom and requires the inclusion of many physics processes. Building on the success of the SciDAC-1 Accelerator Science and Technology project, the SciDAC-2 Community Petascale Project for Accelerator Science and Simulation (ComPASS) is developing a comprehensive set of interoperable components for beam dynamics, electromagnetics, electron cooling, and laser/plasma acceleration modelling. ComPASS is providing accelerator scientists the tools required to enable the necessary accelerator simulation paradigm shift from high-fidelity single physics process modeling (covered under SciDAC1) to high-fidelity multiphysics modeling. Our computational frameworks have been used to model the behavior of a large number of accelerators and accelerator R&D experiments, assisting both their design and performance optimization. As parallel computational applications, the ComPASS codes have been shown to make effective use of thousands of processors.

  8. Commnity Petascale Project for Accelerator Science and Simulation: Advancing Computational Science for Future Accelerators and Accelerator Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Spentzouris, Panagiotis; /Fermilab; Cary, John; /Tech-X, Boulder; Mcinnes, Lois Curfman; /Argonne; Mori, Warren; /UCLA; Ng, Cho; /SLAC; Ng, Esmond; Ryne, Robert; /LBL, Berkeley

    2008-07-01

    The design and performance optimization of particle accelerators is essential for the success of the DOE scientific program in the next decade. Particle accelerators are very complex systems whose accurate description involves a large number of degrees of freedom and requires the inclusion of many physics processes. Building on the success of the SciDAC1 Accelerator Science and Technology project, the SciDAC2 Community Petascale Project for Accelerator Science and Simulation (ComPASS) is developing a comprehensive set of interoperable components for beam dynamics, electromagnetics, electron cooling, and laser/plasma acceleration modeling. ComPASS is providing accelerator scientists the tools required to enable the necessary accelerator simulation paradigm shift from high-fidelity single physics process modeling (covered under SciDAC1) to high-fidelity multi-physics modeling. Our computational frameworks have been used to model the behavior of a large number of accelerators and accelerator R&D experiments, assisting both their design and performance optimization. As parallel computational applications, the ComPASS codes have been shown to make effective use of thousands of processors.

  9. Toward Production From Gas Hydrates: Current Status, Assessment of Resources, and Simulation-Based Evaluationof Technology and Potential

    Energy Technology Data Exchange (ETDEWEB)

    Reagan, Matthew; Moridis, George J.; Collett, Timothy; Boswell, Ray; Kurihara, M.; Reagan, Matthew T.; Koh, Carolyn; Sloan, E. Dendy

    2008-02-12

    Gas hydrates are a vast energy resource with global distribution in the permafrost and in the oceans. Even if conservative estimates are considered and only a small fraction is recoverable, the sheer size of the resource is so large that it demands evaluation as a potential energy source. In this review paper, we discuss the distribution of natural gas hydrate accumulations, the status of the primary international R&D programs, and the remaining science and technological challenges facing commercialization of production. After a brief examination of gas hydrate accumulations that are well characterized and appear to be models for future development and gas production, we analyze the role of numerical simulation in the assessment of the hydrate production potential, identify the data needs for reliable predictions, evaluate the status of knowledge with regard to these needs, discuss knowledge gaps and their impact, and reach the conclusion that the numerical simulation capabilities are quite advanced and that the related gaps are either not significant or are being addressed. We review the current body of literature relevant to potential productivity from different types of gas hydrate deposits, and determine that there are consistent indications of a large production potential at high rates over long periods from a wide variety of hydrate deposits. Finally, we identify (a) features, conditions, geology and techniques that are desirable in potential production targets, (b) methods to maximize production, and (c) some of the conditions and characteristics that render certain gas hydrate deposits undesirable for production.

  10. The role of technology in different framing of scenario-based simulation in nursing education and the impact on design for learning

    DEFF Research Database (Denmark)

    Nortvig, Anne-Mette; Jørnø, Rasmus Leth Vergmann; Gundersen, Peter Bukovica

    2013-01-01

    Scenarios for simulation in nurse education are often designed around specialized technological equipment such as full-sized programmable manikins in order to achieve a high level of fidelity and credibility. The scripted scenarios are performed or played out by students as part of their training......, and provide guidance in prioritizing and relevant criteria for professional judgment. In such a design technology plays an active role in the exploration and reflection on the students’ skill progression. The emphasis is on an education of attention wherein the students’ sensitivity and criteria of relevance...... are developed in tandem with her skill as reflection in action. Finally we consider concrete changes in the role technology plays in the two designs. Keywords: Simulation-based learning, technology, nurse education, design for learning....

  11. THREE-DIMENSIONAL FINITE-ELEMENT SIMULATION OF STRETCHING TECHNOLOGICAL PARAMETERS bt/h AND bb/h OF HEAVY FORGINGS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A three-dimensional finite-element simulation of stretching technological parameters of heavy forgings is performed by using ANSYS program. The law of internal stress distribution with different bt/h (tool width ratio) and different bb/h (blank width ratio) is studied. Consequently, the critical tool width ratio( bt/h )cr and blank width ratio( bb/h )cr leading no bi-axial tension are obtained. It lays a credible foundation for designing reasonable stretching technology.

  12. Numerical Simulation of Plasma-Dynamical Processes in the Technological Inductively Coupled RF Plasmatron with Gas Cooling

    Directory of Open Access Journals (Sweden)

    Yu. M. Grishin

    2016-01-01

    Full Text Available The electrodeless inductively coupled RF plasmatron (ICP torches became widely used in various fields of engineering, science and technology. Presently, owing to development of new technologies to produce very pure substances, nanopowders, etc., there is a steadily increasing interest in the induction plasma. This generates a need for a broad range of theoretical and experimental studies to optimize the design and technological parameters of different ICP equipment.The paper presents a numerical model to calculate parameters of inductively coupled RF plasmatron with gas-cooling flow. A finite volume method is used for a numerical solution of a system of Maxwell's and heat transfer equations in the application package ANSYS CFX (14.5. The pseudo-steady approach to solving problems is used.A numerical simulation has been computed in the application package ANSYS CFX (14.5 for a specific design option of the technological ICP, which has a three-coils inductor and current amplitude in the range J к = 50-170 A (3 MHz. The pure argon flows in the ICP. The paper discusses how the value of discharge current impacts on the thermodynamic parameters (pressure, temperature and the power energy in discharge zone. It shows that the ICP can generate a plasma stream with a maximum temperature of about 10 kK and an output speed of 10-15 m/s. The work determines a length of the plasma stream with a weight average temperature of more than 4 kK. It has been found that in order to keep the quartz walls in normal thermal state, the discharge current amplitude should not exceed 150 A. The paper shows the features of the velocity field distribution in the channel of the plasma torch, namely, the formation of vortex in the position of the first coil. The results obtained are important for calculating the dynamics of heating and evaporation of quartz particles in the manufacturing processes for plasma processing of quartz concentrate into high-purity quartz and

  13. Integrated Use of Tools and Technologies for Rapidly Prototyping Simulated Data Products of Future NASA Observing Systems For Evaluation in Applications of National Importance

    Science.gov (United States)

    O'Hara, C. G.; Moorhead, R.; Shaw, D.; Shrestha, B.; Ross, K.; Prados, D.; Russell, J.; Ryan, R. E.

    2006-12-01

    NASA sponsored "Rapid Prototyping Capability" (RPC) research activities of the Mississippi Research Consortium are aimed at developing infrastructure and experiments to evaluate data products from future NASA observing systems in applications, models or decision support tools of national importance. The RPC will host a wide variety of experiments, many of which will require the simulation of data streams to approximate products from future NASA observing systems. To simulate data from a future observing system, a variety of tools and technologies must be employed in an integrated computational workflow. Future data product simulations will typically involve using data products from currently operational science data mission observing systems to provide inputs to a process wherein data will be extracted and manipulated to provide products that approximate the spectral, spatial, radiometric, and temporal characteristics of planned future sensors. The integration of tools and technologies and adapting interfaces for ease of use will enable researchers to test a variety of simulations to efficiently determine an acceptable set of procedures whereby a simulated data product may be derived from existing data sources. Interactive research and testing of data product simulation scenarios will strongly leverage NASA tools and technologies such as the HDF Extraction to GeoTiff tool (HEG2.7) to extract large volumes of data in batch mode, the Time-Series Product Toolkit (TSPT) to evaluate methods for data fusion, de-noising, and creating multi-temporal composites, and the Application Research Toolbox (ART) to manipulate data product characteristics in the simulation process. Given an accepted simulation configuration generated by a set of methods and a documented process workflow, the process will be computationally implemented using Mississippi State University's Temporal Map Algebra (TMA) tools which will enable handling large data sets, computing efficiently the desired

  14. Sports aerobics simulation system based on VR technology is designed%基于VR技术的体育健美操仿真系统设计

    Institute of Scientific and Technical Information of China (English)

    江艳平

    2014-01-01

    文章主要从VR技术原理出发,分析了VR技术中使用的软硬件系统,讨论了健美操仿真的关键技术,最后对其在健美操运动中应用可行性做了分析研究。%The mainprinciple from VR technology,analyzes the hardware and software systems used in VR technology,discusses the key technologies aerobics simulation, and finally its application in sports aerobics done feasibility analysis.

  15. 主动来流模拟技术试验研究%Studies on Active Flow Simulation Technology

    Institute of Scientific and Technical Information of China (English)

    张冠华; 赵林; 葛耀君

    2014-01-01

    With the development of the bridge span, the structural response of long-span bridges is more sensitive to flow turbulence and its load. Wind tunnel test should be fine as the traditional method, to accu-rately simulate the natural wind properties. On the basis of full investigation of existing research results, with active flow simulation technology based on active controlled tunnel and active vibration wing, and in order to adjust energy distribution, synchronously acquire real-time multipoint test data of flow velocity and aerodyne component, the spatial synchronization conversion method was put forward to solve accurate test problems of real flow field, and fully simulate a number of aerodynamic forces with effective methods and means for more precise analysis were provided. With the active flow simulation technology and numerical analysis, the research on spectral spatial correlation of narrowband spectrum and broadband spectrum has been conducted to analyze and interpret some typical aerodynamic forces phenomenon. Some meaningful conclusions were drawn and reference materials for engineering applications were provided.%随着现代大跨度桥梁不断向长大化方向发展,风荷载作用越来越突出,风洞试验作为研究的最重要手段需要精细化,以准确模拟自然风特性。  本文在充分调研基础上,进行主动来流模拟技术研究,基于主动控制风洞,制作主动振动机翼,调整不同来流的能量分配,实现了多点来流风速与气动力分量等试验数据实时同步采集,提出空间同步转换法,解决了试验模型处流场真实状况准确测试问题,充分模拟多项气动力,为更加精细化分析提供有效的方法和手段。  利用主来流模拟技术,通过数值分析,从理论上对窄带谱、宽带谱来流的空间相关性进行研究,分析解释了部分典型气动力现象,得到有意义结论,为深入研究提供参考资料。

  16. Technology Advancements for Active Remote Sensing of Carbon Dioxide From Space using the ASCENDS CarbonHawk Experiment Simulator

    Science.gov (United States)

    Obland, M. D.; Liu, Z.; Campbell, J. F.; Lin, B.; Kooi, S. A.; Carrion, W.; Hicks, J.; Fan, T. F.; Nehrir, A. R.; Browell, E. V.; Meadows, B.; Davis, K. J.

    2016-12-01

    This work describes advances in critical lidar technologies and techniques developed as part of the ASCENDS CarbonHawk Experiment Simulator (ACES) system for measuring atmospheric column carbon dioxide (CO2) mixing ratios in support of the NASA Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission. The ACES design demonstrates advancements in: (1) enhanced power-aperture product through the use and operation of multiple co-aligned laser transmitters and a multi-aperture telescope design; (2) high-efficiency, high-power Erbium-Doped Fiber Amplifiers (EDFAs); (3) high-bandwidth, low-noise HgCdTe detector and transimpedence amplifier (TIA) subsystem capable of long-duration operation; and (4) advanced algorithms for cloud and aerosol discrimination. The ACES instrument, an Intensity-Modulated Continuous-Wave (IM-CW) lidar, was designed for high-altitude aircraft operations and can be directly applied to space instrumentation to meet the ASCENDS mission requirements. Specifically, the lidar simultaneously transmits three IM-CW laser beams from the high power EDFAs operating near 1571 nm. The outgoing laser beams are aligned to the field of view of three fiber-coupled 17.8-cm diameter telescopes, and the backscattered light collected by the same three telescopes is sent to the detector/TIA subsystem, which has a bandwidth of 4.9 MHz and operates service-free with a tactical Dewar and cryocooler. The electronic bandwidth is only slightly higher than 1 MHz, effectively limiting the noise level. Two key laser modulation approaches are being tested to significantly mitigate the effects of thin clouds on the retrieved CO2 column amounts. This work provides an over view of these technologies, the modulation approaches, and results from recent test flights during the Atmospheric Carbon and Transport - America (ACT-America) Earth Venture Suborbital flight campaign.

  17. Toward production from gas hydrates: Current status, assessment of resources, and simulation-based evaluation of technology and potential

    Science.gov (United States)

    Moridis, G.J.; Collett, T.S.; Boswell, R.; Kurihara, M.; Reagan, M.T.; Koh, C.; Sloan, E.D.

    2009-01-01

    Gas hydrates (GHs) are a vast energy resource with global distribution in the permafrost and in the oceans. Even if conservative estimates are considered and only a small fraction is recoverable, the sheer size of the resource is so large that it demands evaluation as a potential energy source. In this review paper, we discuss the distribution of natural GH accumulations, the status of the primary international research and development (R&D) programs, and the remaining science and technological challenges facing the commercialization of production. After a brief examination of GH accumulations that are well characterized and appear to be models for future development and gas production, we analyze the role of numerical simulation in the assessment of the hydrate-production potential, identify the data needs for reliable predictions, evaluate the status of knowledge with regard to these needs, discuss knowledge gaps and their impact, and reach the conclusion that the numerical-simulation capabilities are quite advanced and that the related gaps either are not significant or are being addressed. We review the current body of literature relevant to potential productivity from different types of GH deposits and determine that there are consistent indications of a large production potential at high rates across long periods from a wide variety of hydrate deposits. Finally, we identify (a) features, conditions, geology and techniques that are desirable in potential production targets; (b) methods to maximize production; and (c) some of the conditions and characteristics that render certain GH deposits undesirable for production. Copyright ?? 2009 Society of Petroleum Engineers.

  18. Método para mapeamento de locos controladores de características oligogênicas Genetic mapping of oligogenic traits using maximum likehood functions

    Directory of Open Access Journals (Sweden)

    Rodrigo Barros Rocha

    2010-02-01

    Full Text Available Características oligogênicas de distribuição discreta e expressão governada por poucos genes de maior efeito têm se mostrado importantes na condução dos programas de melhoramento, com destaque para a resposta de resistência das plantas às doenças. Métodos tradicionais de detecção de QTL's, que pressupõem normalidade e herança governada por múltiplos fatores, não deveriam ser utilizados para mapeamento dessas características de distribuição discreta e interação epistática predominante. O objetivo deste trabalho é avaliar os resultados de um método para mapeamento e detecção de locos controladores da expressão de características oligogênicas, OTL's (Oligogenic Trait Loci. Esse método, definido como MMCO (Método de Mapeamento de Características Oligogênicas, utiliza funções de verossimilhança para obtenção de estimativas de ligação fatorial entre locos marcadores e locos controladores de características oligogênicas. Os resultados indicam que o método foi adequado para detecção de OTL's em populações F2 relativamente pequenas, compostas por 200 indivíduos, e que a determinação a priori do padrão de herança é condição necessária para a utilização dessa estratégia, que se diferencia por atender as pressuposições de análise, não necessitar de informação prévia de ordenamento entre as marcas e por permitir a obtenção de estimativas a partir da informação contida em todas as classes genotípicas.Oligogenic traits are distinguished by their heritage ruled by higher effect genes and by their importance for cultivated plants, with emphasis to the plant disease resistance inheritance. The qualitative nature and epistatic interaction of these traits results in a heritage pattern that should not be interpreted through traditional QTL detection strategies. The objective of this work was to propose a method for Oligogenic Traits Loci (OTL detection. This method, defined as Oligogenic Trait

  19. Reflections on the Application of Fire Risk Simulation Technology%关于火灾模拟技术应用和发展的思考

    Institute of Scientific and Technical Information of China (English)

    王卫剑

    2011-01-01

    火灾模拟技术为性能化设计提供依据和分析手段,促进了消防技术的发展。对火灾模拟技术进行了综述,介绍了火灾模拟技术在防灭火工作中的应用,对我国火灾模拟技术发展进行了展望。%Fire risk simulation technology provides the means for performance-based fire prevention design and analysis and promotes the development of fire technology.This paper reviews fire risk simulation technology and introduces its application in fire prevention,and its future direction.

  20. The Effect of Student Learning Styles on the Learning Gains Achieved When Interactive Simulations Are Coupled with Real-Time Formative Assessment via Pen-Enabled Mobile Technology

    CERN Document Server

    Kowalski, F V

    2013-01-01

    This paper describes results from a project in an undergraduate engineering physics course that coupled classroom use of interactive computer simulations with the collection of real-time formative assessment using pen-enabled mobile technology. Interactive simulations (free or textbook-based) are widely used across the undergraduate science and engineering curriculia to help actively engaged students increase their understanding of abstract concepts or phenomena which are not directly or easily observable. However, there are indications in the literature that we do not yet know the pedagogical best practices associated with their use to maximize learning. This project couples student use of interactive simulations with the gathering of real-time formative assessment via pen-enabled mobile technology (in this case, Tablet PCs). The research question addressed in this paper is: are learning gains achieved with this coupled model greater for certain types of learners in undergraduate STEM classrooms? To answer t...

  1. Research and Development of Virtual Maintenance Simulation Technology%虚拟维修仿真技术的研究与进展

    Institute of Scientific and Technical Information of China (English)

    王文举; 李光耀

    2011-01-01

    近年来虚拟维修仿真技术广泛应用于维修性设计、保障性规划及人员培训三大应用领域并取得了巨大的经济和社会效益,成为了当前研究热点。对此分析归纳了该领域内众多国内外虚拟维修仿真案例。针对仿真对象的扩展及新技术的应用,提出了虚拟维修仿真技术的明确定义;总结出了虚拟维修仿真技术的实现流程,深入探讨了该技术研究所涉及的一系列关键技术问题;比较分析了仿真过程中所需的软件实现平台;最后对其未来的研究方向进行了展望。%It is virtual maintenance simulation technology that has been widely used in the three fields of maintainability design,supportability planning,and maintenance personnel training and achieved great economic and social benefits.Therefore,it becomes the current research hotspot.So numerous cases of virtual maintenance simulation at home and abroad were analyzed and summarized.In view of the extension of simulation object and the application of new technology,the new definition of virtual maintenance simulation technology was proposed.Realization flow of the virtual maintenance simulation technology was summarized and a series of involved key technological problems were investigated.Many related popular software realization platforms were analyzed and compared.Finally,the prospect of the future work in this area was also presented.

  2. El baile de las que sobran, el contrato como estrategia de adaptación en Loco Afán

    Directory of Open Access Journals (Sweden)

    Alejandro Rossi Brotfeld

    2015-08-01

    Full Text Available A partir de la oposición entre los conceptos de masoquismo y sadismo, en este trabajo se realiza un análisis de cuatro textos de Loco afán: crónicas de sidario (1996 de Pedro Lemebel: “La noche de los visones”, “La Regine de Aluminios el Mono”, “Atada a un granito de arena” y “Su ronca risa loca”. A partir de las etimologías literarias de ambos conceptos, propongo que las nociones de masoquismo y sadismo describen la manera en que se establecen lazos sociales En breve, si el masoquismo implica relaciones horizontales (contractuales, el sadismo implica relaciones verticales. Sobre esta base conceptual, el objetivo general del trabajo es identificar el tipo de vínculo social (¿masoquista o sádico? que establecen las travestis presentes en las crónicas de Loco afán. Se propone que, en las crónicas de Lemebel, el lazo es masoquista y no sádico pues sus personajes protagónicos (miembros de minorías sexuales y políticas suturan su posición de exclusión social a través del comercio sexual. Al saberse excluidos, estos personajes desarrollan una relación masoquista en el trato con el otro (cliente ocasional. En suma, en las crónicas de Lemebel el carácter contractual del lazo masoquista que establecen en sus prácticas de comercio sexual les permite satisfacer la fantasía de la legalidad de su condición sexual: la forma en que se produce el contrato en las crónicas siempre involucra el cuerpo. Se concluye que es este tipo de prácticas el que, paradójicamente, excluye a la travesti de la sociedad en primera instancia (por reflejar superficialmente la condición sexual que tiene, y al mismo tiempo, es la herramienta que utiliza para poder construir su fantasía e inscribirse en el tejido social.

  3. 硬件在环仿真在轮机模拟器的应用探讨与其关键技术%Application of Hardware-in-the-loop Simulation in Engine room Simulator and Its Essential Technology

    Institute of Scientific and Technical Information of China (English)

    高政宁

    2012-01-01

      介绍了一种硬件在环仿真在中央冷却系统的假想设计,阐述了硬件在环仿真的基本概念,并对其关键技术从软硬件两个方面进行了探讨,为硬件在回路仿真在轮机模拟器的运用提供参考。%  this passage introduces a design of application of hardware-in-the-loop simulation in center cooling system, and describes some concepts of hardware-in-the-loop simulation. It takes essential technology from hardware to software into discussion. this can be ref-erence to application of hardware-in-the-loop simulation in engine room simulator.

  4. 刑事科学技术综合模拟实训的改革%Reform of Criminal Science and Technology Integrated Simulation Training

    Institute of Scientific and Technical Information of China (English)

    姚琴; 吴玉红

    2015-01-01

    Criminal Science and Technology is a comprehensive simulation training in criminal science and technology tea-ching indispensable part, it is an important means to strengthen students' theoretical knowledge of criminal science and tech-nology and improve practical skills. In this paper, the actual situation of education in recent years, the status of criminal sci-ence and technology integrated simulation training is analyzed and described, and the Reform of the integrated simulation training provided a useful exploration and try.%刑事科学技术综合模拟实训是刑事科学技术专业教学中不可缺少的环节,是巩固学生刑事科学技术理论知识并提高实际操作技能的重要手段。本文结合近年来的教学实际情况,对刑事科学技术综合模拟实训的现状进行了分析与阐述,对综合模拟实训的教学改革进行了有益的探索与尝试。

  5. The subsurface geology of Río Tinto: material examined during a simulated Mars drilling mission for the Mars Astrobiology Research and Technology Experiment (MARTE).

    Science.gov (United States)

    Prieto-Ballesteros, Olga; Martínez-Frías, Jesús; Schutt, John; Sutter, Brad; Heldmann, Jennifer L; Bell, Mary Sue; Battler, Melissa; Cannon, Howard; Gómez-Elvira, Javier; Stoker, Carol R

    2008-10-01

    The 2005 Mars Astrobiology Research and Technology Experiment (MARTE) project conducted a simulated 1-month Mars drilling mission in the Río Tinto district, Spain. Dry robotic drilling, core sampling, and biological and geological analytical technologies were collectively tested for the first time for potential use on Mars. Drilling and subsurface sampling and analytical technologies are being explored for Mars because the subsurface is the most likely place to find life on Mars. The objectives of this work are to describe drilling, sampling, and analytical procedures; present the geological analysis of core and borehole material; and examine lessons learned from the drilling simulation. Drilling occurred at an undisclosed location, causing the science team to rely only on mission data for geological and biological interpretations. Core and borehole imaging was used for micromorphological analysis of rock, targeting rock for biological analysis, and making decisions regarding the next day's drilling operations. Drilling reached 606 cm depth into poorly consolidated gossan that allowed only 35% of core recovery and contributed to borehole wall failure during drilling. Core material containing any indication of biology was sampled and analyzed in more detail for its confirmation. Despite the poorly consolidated nature of the subsurface gossan, dry drilling was able to retrieve useful core material for geological and biological analysis. Lessons learned from this drilling simulation can guide the development of dry drilling and subsurface geological and biological analytical technologies for future Mars drilling missions.

  6. Ground Freezing Fog Simulation Technology Study%开放式结冰条件模拟技术研究

    Institute of Scientific and Technical Information of China (English)

    李志茂; 李革萍; 王大伟; 沈东

    2013-01-01

    在-1~-9益的环境温度条件下,采用开放式结冰条件模拟技术可以为民机或军机发动机短舱防冰系统性能试验模拟出合适的结冰气象条件。采用气液两相喷嘴模拟水雾结冰环境时,所采用气体和液体的纯度是过冷水滴产生的先决条件,气液两相压差、风洞吹风速度和试验对象距离是影响结冰气象参数的关键因子。采用改造后的FM-100传感器可实现对结冰气象参数的实时测量。通过升降机构、小角度俯仰和万向轮等辅助结构设计,开放式结冰条件模拟系统可以满足不同试验对象的试验要求,可以适应不同风向的试验环境,具备非常广阔的推广应用前景。%Ground freezing fog simulation technology can generate icing condition for commercial or military air-craft nacelle anti-ice system performance evaluation under -1~-9℃. Purity of water and air used for fog genera-ting is the precondition, icing parameter is impacted by diff-pressure of liquid-gas, wind tunnel velocity and dis-tance between test article and test rig. Rectified FM-100 sensor can be used for icing parameter measurement, rig lift, small angle pitching and universal mechanical structure design make the fog simulation rig can satisfy the re-quirements of different test articles and wind directions.

  7. 水利工程虚拟仿真技术应用研究%Application research on virtual simulation technology in water conservancy projects

    Institute of Scientific and Technical Information of China (English)

    杨启贵

    2015-01-01

    虚拟仿真技术利用计算机模拟方法来重现实际系统中发生的本质过程,具有沉浸性、交互性、虚幻性、逼真性等特点. 水利工程虚拟仿真是水利信息化的重要表现手段. 针对该技术在水利工程中的应用,开展了对现行三维软件集成、二次开发和功能扩展的研究,实现了水利工程功能性仿真与视景仿真功能,并结合案例介绍了在水利工程勘测设计、运行管理、防洪调度中的应用情况,展望了水利工程虚拟仿真技术的应用前景.%The virtual simulation technology uses the computer simulation to reproduce the essence processes in the real sys-tem, which is immersive, interactive, illusion and verisimilitude, etc. The virtual simulation technology in water conservancy projects is an important expressive means in the water resources informatization field. Aiming at the application of the technology in the water conservancy projects, the research on integrating, secondary developing and function expansion of the existing 3D software are carried out, so the functional simulation and visual simulation of water conservancy projects are realized. The appli-cations in survey and design, operation and management, flood control and scheduling of the water conservancy projects are de-scribed combining with some practical cases, and the application prospects of the technology in water conservancy projects are discussed.

  8. Novel Chitinase Gene LOC_Os11g47510 from Indica Rice Tetep Provides Enhanced Resistance against Sheath Blight Pathogen Rhizoctonia solani in Rice

    Directory of Open Access Journals (Sweden)

    Tilak R. Sharma

    2017-04-01

    Full Text Available Sheath blight disease (ShB, caused by the fungus Rhizoctonia solani Kühn, is one of the most destructive diseases of rice (Oryza sativa L., causing substantial yield loss in rice. In the present study, a novel rice chitinase gene, LOC_Os11g47510 was cloned from QTL region of R. solani tolerant rice line Tetep and used for functional validation by genetic transformation of ShB susceptible japonica rice line Taipei 309 (TP309. The transformants were characterized using molecular and functional approaches. Molecular analysis by PCR using a set of primers specific to CaMv 35S promoter, chitinase and HptII genes confirmed the presence of transgene in transgenic plants which was further validated by Southern hybridization. Further, qRT-PCR analysis of transgenic plants showed good correlation between transgene expression and the level of sheath blight resistance among transformants. Functional complementation assays confirmed the effectiveness of the chitinase mediated resistance in all the transgenic TP309 plants with varying levels of enhanced resistance against R. solani. Therefore, the novel chitinase gene cloned and characterized in the present study from the QTL region of rice will be of significant use in molecular plant breeding program for developing sheath blight resistance in rice.

  9. Loco regional failure pattern after lumpectomy and breast irradiation in 4185 patients with T1 and T2 breast cancer. Implications for nodal irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Livi, Lorenzo; Paiar, Fabiola; Simontacchi, Gabriele [Univ. of Florence (Italy). Dept. of Radiation Oncology] (and others)

    2006-07-15

    The aim of this study is to determinate incidence and risk factors for loco regional failure (LRR) (breast, supraclavicular, axillary and internal mammary nodes) and indications for nodal irradiation. From January 1980 to December 2001, 4185 patients with T1-T2 breast cancer were treated with conservative surgery and whole breast radiotherapy without nodal irradiation at the Univ. of Florence. The median age was 55 years (range 19-86). All patients were followed for a median of eight years (range 3 months to 20 years). Multivariate analysis showed as independent prognostic factors for isolated nodal relapse (NR) the presence of more than three positive lymph nodes (PAN) (p=0.001), angiolymphatic invasion (p=0.002) and pT2 (p=0.02). However, only 4.8% of patients with more than three PAN developed NR as the only site of recurrence. Having one to three PAN was not associated with an increased risk of NR. We believe that it is not necessary to prescribe nodal irradiation to patients with negative or one to three PAN. Regarding patients with more than three PAN, the number of isolated NR is also small to routinely justify a node irradiation.

  10. Crystal Structures of the Scaffolding Protein LGN Reveal the General Mechanism by Which GoLoco Binding Motifs Inhibit the Release of GDP from Gαi *

    Science.gov (United States)

    Jia, Min; Li, Jianchao; Zhu, Jinwei; Wen, Wenyu; Zhang, Mingjie; Wang, Wenning

    2012-01-01

    GoLoco (GL) motif-containing proteins regulate G protein signaling by binding to Gα subunit and acting as guanine nucleotide dissociation inhibitors. GLs of LGN are also known to bind the GDP form of Gαi/o during asymmetric cell division. Here, we show that the C-terminal GL domain of LGN binds four molecules of Gαi·GDP. The crystal structures of Gαi·GDP in complex with LGN GL3 and GL4, respectively, reveal distinct GL/Gαi interaction features when compared with the only high resolution structure known with GL/Gαi interaction between RGS14 and Gαi1. Only a few residues C-terminal to the conserved GL sequence are required for LGN GLs to bind to Gαi·GDP. A highly conserved “double Arg finger” sequence (RΨ(D/E)(D/E)QR) is responsible for LGN GL to bind to GDP bound to Gαi. Together with the sequence alignment, we suggest that the LGN GL/Gαi interaction represents a general binding mode between GL motifs and Gαi. We also show that LGN GLs are potent guanine nucleotide dissociation inhibitors. PMID:22952234

  11. Towards a framework for teaching about information technology risk in health care: Simulating threats to health data and patient safety

    OpenAIRE

    2015-01-01

    In this paper the author describes work towards developing an integrative framework for educating health information technology professionals about technology risk. The framework considers multiple sources of risk to health data quality and integrity that can result from the use of health information technology (HIT) and can be used to teach health professional students about these risks when using health technologies. This framework encompasses issues and problems that may arise from varied ...

  12. Simulation of the Secondary Frequency Control Capability of the Advanced PSH Technology and Its Application to the SMUD System

    Energy Technology Data Exchange (ETDEWEB)

    Koritarov, Vladimir [Argonne National Lab. (ANL), Argonne, IL (United States); Feltes, James [Argonne National Lab. (ANL), Argonne, IL (United States); Kazachkov, Yuriy [Argonne National Lab. (ANL), Argonne, IL (United States)

    2013-11-01

    The Sacramento Municipal Utility District (SMUD), as a typical balancing authority and project team member, was suggested by the Advanced Technology Modeling TFG for testing the models of the advanced pump storage hydro technology newly developed in the course of the DOE project and for demonstration of the potential benefits of this technology.

  13. Using High-Technology Simulators to Prepare Anesthesia Providers Before Implementation of a New Electronic Health Record Module: A Technical Report.

    Science.gov (United States)

    Weintraub, Ari Y; Deutsch, Ellen S; Hales, Roberta L; Buchanan, Newton A; Rock, Whitney L; Rehman, Mohamed A

    2017-06-01

    Learning to use a new electronic anesthesia information management system can be challenging. Documenting anesthetic events, medication administration, and airway management in an unfamiliar system while simultaneously caring for a patient with the vigilance required for safe anesthesia can be distracting and risky. This technical report describes a vendor-agnostic approach to training using a high-technology manikin in a simulated clinical scenario. Training was feasible and valued by participants but required a combination of electronic and manual components. Further exploration may reveal simulated patient care training that provides the greatest benefit to participants as well as feedback to inform electronic health record improvements.

  14. 有限元仿真在机械制造技术基础课程教学中的应用%Application of ifnite element simulation technology in teaching fundamentals of mechanical manufacturing technology

    Institute of Scientific and Technical Information of China (English)

    隋荣娟

    2014-01-01

    介绍了有限元软件ANSYS的基本功能和应用范围,以模拟金属的切削、挤压等过程为例,分析了有限元仿真模拟在机械制造技术基础课程教学中的应用。有限元仿真模拟应用于机械制造技术基础课程教学中,具有节约教学学时、提高教学质量等优点。%The basic function and application of the ifnite element software, ANSYS, is introduces. Taking the simulation of metal cutting and the extrusion process for example, the application of finite element simulation technology in teaching fundamentals of mechanical manufacturing technology is analyzed. The ifnite element simulation technology used in instruction can save the teaching hours, improve teaching quality, etc.

  15. Technological simulation of the process of filtering water for human consumption; Simulacion tecnologica del proceso de filtracion en aguas para el consumo humano

    Energy Technology Data Exchange (ETDEWEB)

    Marquez Canosa, E.; Herrera Vasconselo, T.; Marques, R.J.; Mondelo Rodriguez, A.; Tito Rigau, J.

    1998-12-01

    Theoretical bases of filtration process technological simulation through porous media state that physical fundamental of these phenomena does not change and acting torches change just in magnitude, but not in natural, inside a defined bound. In this paper is apply a methodology for determining theoretical parameters, which one are characteristics of separated particles intensity, adhesion intensity and particles penetration velocity inside packed bed. Parameters above mentioned were evaluate in fifteen sand filters and fifteen zeolite filters suing output water of coagulation-flocculation process of a potabilization plant, in a laboratory scale. Through technological simulation it was possible to make clear process filtration kinetic also to determine optimum operation and design parameters. (Author) 28 refs.

  16. The role of technology in different framings of scenario-based simulation in nursing education and the impact on design for learning

    DEFF Research Database (Denmark)

    Nortvig, Anne-Mette; Jørnø, Rasmus Leth; Gundersen, Peter

    2013-01-01

    Scenarios for simulation in nurse education are often designed around specialized technological equipment such as full-sized programmable manikins in order to achieve a high level of fidelity and credibility. The scripted scenarios are performed or played out by students as part of their training......, provide guidance in prioritizing and relevant criteria for professional judgment. In such a design technology plays an active role in the exploration and reflection on the students’ skill progression. The emphasis is on an education of attention wherein the students’ sensitivity and criteria of relevance...... opportunities for reflection on action. In such designs technology withdraws into the background as part of an evaluation of how realistic the scenario is deemed. The emphasis is on evaluation of the performance. In this paper we would first like to offer an analysis of the above approach as evaluative as we...

  17. Simulation and performance analysis of 110 kWp grid-connected photovoltaic system for residential building in India: A comparative analysis of various PV technology

    Directory of Open Access Journals (Sweden)

    Akash Kumar Shukla

    2016-11-01

    Full Text Available System simulation is necessary to investigate the feasibility of Solar PV system at a given location. This study is done to evaluate the feasibility of grid connected rooftop solar photovoltaic system for a residential Hostel building at MANIT, Bhopal, India (Latitude: 23° 16′ N, Longitude: 77° 36′ E. The study focuses on the use of Solargis PV Planner software as a tool to analyze the performance a 110 kWp solar photovoltaic rooftop plant and also compares the performances of different PV technologies based on simulated energy yield and performance ratio. Solargis proves to easy, fast, accurate and reliable software tool for the simulation of solar PV system.

  18. [Key technologies and implementation of the medical equipment road transportation simulation platform based on 6-DOF parallel robots].

    Science.gov (United States)

    Pei, Yidong; Pei, Baoqing; Li, Hui; Fan, Yubo

    2013-01-01

    In view of the shortage of medical equipment road transportation simulation platform, we put forward a road transportation simulation method based on 6-DOF parallel robots. A 3D road spectrum model was built by the improvement of the harmonic superposition method. The simulation model was then compared with the standard model to verify its performance. Taking the road spectrum as the excitation, we could get the robot motion data to control the parallel robot through the S-shaped linear interpolation of the absolute position. It can simulate the movement of vehicles with different speed under various road conditions efficiently and accurately.

  19. Damage evaluation for crops exposed to a simulated leakage of geologically stored CO2 using hyperspectral imaging technology

    Science.gov (United States)

    Burud, Ingunn; Moni, Christophe; Flø, Andreas; Rolstad Denby, Cecilie; Rasse, Daniel

    2013-04-01

    Facilities for the geological storage of carbon dioxide (CO2) as part of carbon capture and storage (CCS) schemes will be designed to prevent any leakage from the defined 'storage complex'. However, even though the risk is of low probability, the precautionary principle requires that near surface environments that might be at risk be thoroughly monitored to detect a leak, were it to happen. Among all currently proposed monitoring methods, only hyperspectral imaging of vegetation stress response allows one to scan large areas rapidly and in detail. Until now, however, only a handful of studies have been carried out on using this novel technology. The aim of the present communication was to characterize the impacts that a simulated CO2 leak might have on the hyperspectral signature of a Norwegian oats crop. In order to test the effects of different intensity of leakage, a CO2 exposure field experiment was designed to create a longitudinal CO2 gradient. For this purpose a gas supply pipe was inserted at one end of a 6m by 3m experimental plot at the base of a 45 cm thick layer of sand buried 40 cm below the surface under a silt loam plough layer. CO2 was then injected at a rate of 2l.min-1 just after the oats had germinated at the end of June, and Facilities for the geological storage of carbon dioxide (CO2) as part of carbon capture and storage (CCS) schemes will be designed to prevent any leakage from the defined 'storage complex'. However, even though the risk is of low probability, the precautionary principle requires that near surface environments that might be at risk be thoroughly monitored to detect a leak, were it to happen. Among all currently proposed monitoring methods, only hyperspectral imaging of vegetation stress response allows one to scan large areas rapidly and in detail. Until now, however, only a handful of studies have been carried out on using this novel technology. The aim of the present communication was to characterize the impacts that a

  20. Technology, Pedagogy, and Epistemology: Opportunities and Challenges of Using Computer Modeling and Simulation Tools in Elementary Science Methods

    Science.gov (United States)

    Schwarz, Christina V.; Meyer, Jason; Sharma, Ajay

    2007-01-01

    This study infused computer modeling and simulation tools in a 1-semester undergraduate elementary science methods course to advance preservice teachers' understandings of computer software use in science teaching and to help them learn important aspects of pedagogy and epistemology. Preservice teachers used computer modeling and simulation tools…

  1. Developmental and loco-like effects of a swainsonine-induced inhibition of α-mannosidase in the honey bee, Apis mellifera

    Directory of Open Access Journals (Sweden)

    Laura Wedd

    2017-03-01

    Full Text Available Background Deficiencies in lysosomal a-mannosidase (LAM activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey bee population suggesting that they might be beneficial in certain contexts and cannot be eliminated by natural selection. Methods We have used a combination of enzymology, molecular biology and metabolomics to characterise the catalytic properties of honey bee LAM (AmLAM and then used an indolizidine alkaloid swainsonine to inhibit its activity in vitro and in vivo. Results We show that AmLAM is inhibited in vitro by swainsonine albeit at slightly higher concentrations than in other animals. Dietary exposure of growing larvae to swainsonine leads to pronounced metabolic changes affecting not only saccharides, but also amino acids, polyols and polyamines. Interestingly, the abundance of two fatty acids implicated in epigenetic regulation is significantly reduced in treated individuals. Additionally, swainsonie causes loco-like symptoms, increased mortality and a subtle decrease in the rate of larval growth resulting in a subsequent developmental delay in pupal metamorphosis. Discussion We consider our findings in the context of cellular LAM function, larval development, environmental toxicity and colony-level impacts. The observed developmental heterochrony in swainsonine-treated larvae with lower LAM activity offer a plausible explanation for the existence of epialleles with impaired LAM expression. Individuals carrying such epialleles provide an additional level of epigenetic diversity that could be beneficial for the functioning of a colony whereby more flexibility in timing of adult emergence might be useful for task allocation.

  2. Developmental and loco-like effects of a swainsonine-induced inhibition of α-mannosidase in the honey bee, Apis mellifera

    Science.gov (United States)

    Wedd, Laura; Ashby, Regan; Foret, Sylvain

    2017-01-01

    Background Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey bee population suggesting that they might be beneficial in certain contexts and cannot be eliminated by natural selection. Methods We have used a combination of enzymology, molecular biology and metabolomics to characterise the catalytic properties of honey bee LAM (AmLAM) and then used an indolizidine alkaloid swainsonine to inhibit its activity in vitro and in vivo. Results We show that AmLAM is inhibited in vitro by swainsonine albeit at slightly higher concentrations than in other animals. Dietary exposure of growing larvae to swainsonine leads to pronounced metabolic changes affecting not only saccharides, but also amino acids, polyols and polyamines. Interestingly, the abundance of two fatty acids implicated in epigenetic regulation is significantly reduced in treated individuals. Additionally, swainsonie causes loco-like symptoms, increased mortality and a subtle decrease in the rate of larval growth resulting in a subsequent developmental delay in pupal metamorphosis. Discussion We consider our findings in the context of cellular LAM function, larval development, environmental toxicity and colony-level impacts. The observed developmental heterochrony in swainsonine-treated larvae with lower LAM activity offer a plausible explanation for the existence of epialleles with impaired LAM expression. Individuals carrying such epialleles provide an additional level of epigenetic diversity that could be beneficial for the functioning of a colony whereby more flexibility in timing of adult emergence might be useful for task allocation. PMID:28321369

  3. 局部晚期鼻咽癌综合治疗研究进展%Combined Treatment of Loco-regionally Advanced Nasopharyngeal Carcinoma

    Institute of Scientific and Technical Information of China (English)

    高云生

    2012-01-01

    局部晚期鼻咽癌的治疗以放、化综合治疗为主,方案有诱导化疗、同期放化疗和辅助化疗及其不同的组合.同期放化疗(或加辅助化疗)是NCCN指南推荐的治疗方式.鼻咽癌的新辅助化疗虽然对提高总生存作用尚不肯定,但是其高缓解率及减少远处转移的潜能,可能使部分患者受益.含有紫杉类药物的新辅助化疗方案、靶向药物联合同期化疗亦成为临床研究的热点.%Radiotherapies combined with chemotherapy, such as neo-adjuvant chemotherapy, concomitant chemo-radiotherapy, and adjuvant chemotherapy, are recommended in the treatment of loco-regionally advanced nasopharyngeal carcinoma (NPC). Concurrent chemo-radiotherapy is the standard treatment for advanced NPC. Although whether neo-adjuvant chemotherapy could improve the overall survival still remains uncertain, this treatment can increase the response rate and potentially eradicate the subclinical metastasis in patients with advanced NPC. The addition of paclitaxel and cisplatin-based neo-adjuvant chemotherapy has shown potential in terms of therapeutic efficacy and safety. The clinical trials of the neo-adjuvant chemotherapy combined with subsequent chemo-radiotherapy are more widely studied than independent radiotherapy and chemotherapy. Targeted therapy in combination with radiotherapy and chemotherapy is also popular in current studies.

  4. Herança e ligação em locos isoenzimáticos de Caesalpinia echinata L. (pau-brasil. Inheritance and linkage in isozyme loci of Caesalpinia echinata L. (pau-brasil.

    Directory of Open Access Journals (Sweden)

    João del GIUDICE-NETO

    2004-12-01

    Full Text Available Este artigo apresenta o estudo davariação isoenzimática em Caesalpinia echinata L.(pau-brasil. Onze sistemas enzimáticos (ACP,DIA, EST, G6PDH, GOT, LAP, MDH, PGI, PRX,SKDH e 6PGDH codificando dezoito locos (Acp-1,Est-3, Dia-1, G6pdh-1, Got-1, Lap-1, Mdh-1,Mdh-2, Mdh-3, Pgi-1, Pgi-2, Prx-1, Prx-2, Prx-3,Prx-4, Skdh-1, 6pgdh-1 e 6pgdh-2 foraminvestigados. Entre esses locos, Pgi-1 e Got-1foram detectados como monomórficos. Três locos(Mdh-2, G6pdh-1 e 6pgdh-1 não tiveram suaherança analisada devido à ausência de progênies deárvores heterozigotas na amostra. A herançamendeliana simples foi confirmada para dez locos(Acp-1, Dia-1, Est-3, Lap-1, Mdh-1, Mdh-3, Prx-1,Prx-3, Skdh-1 e 6pgdh-2. Três locos (Pgi-2, Prx-2e Prx-4 apresentaram desvios altamentesignificativos (P < 0,01 para a hipótese desegregação regular 1:1. As relações dedesequilíbrios de ligações foram avaliadas em 120pares de locos isoenzimáticos. Seis pares de locosapresentaram ligação: Mdh-3:Dia-1, Mdh-3:Prx-3,6pgdh-1:Pgi-2, 6pgdh-1:Prx-1, 6pgdh-2:Prx-3 ePgi-2:Prx-4.This article presents a study of isozymevariation in Caesalpinia echinata L. (brazilwood.Eleven isozyme systems (ACP, DIA, EST,G6PDH, GOT, LAP, MDH, PGI, PRX, SKDH and6PGDH codifying eighteen loci (Acp-1, Est-3,Dia-1, G6pdh-1, Got-1, Lap-1, Mdh-1, Mdh-2,Mdh-3, Pgi-1, Pgi-2, Prx-1, Prx-2, Prx-3, Prx-4,Skdh-1, 6pgdh-1 and 6pgdh-2 were investigated.Among these loci, Pgi-1 and Got-1 weremonomorphic. Three loci (Mdh-2, G6pdh-1 and6pgdh-1 were not evaluated for inheritance duethe lack of families from heterozygous mothertrees in the sampling. Mendelian inheritance wasconfirmed for ten allozyme loci (Acp-1, Dia-1,Est-3, Lap-1, Mdh-1, Mdh-3, Prx-1, Prx-3, Skdh-1,and 6pgdh-2. Three loci (Pgi-2, Prx-2 and Prx-4showed significant deviations (P < 0.01 from expectedsegregation 1:1 hypothesis. Linkage relationshipswere examined for 120 pairs of allozyme loci.Six pairs of loci showed linked: Mdh-3:Dia-1,Mdh-3:Prx-3, 6

  5. Thermal-comfort analysis and simulation for various low-energy cooling-technologies applied to an office building in a subtropical climate

    Energy Technology Data Exchange (ETDEWEB)

    Chowdhury, Ashfaque Ahmed; Rasul, M.G.; Khan, M.M.K. [College of Engineering and the Built Environment, Faculty of Sciences, Engineering and Health, Central Queensland University, Rockhampton, Qld 4702 (Australia)

    2008-06-15

    Simulation of buildings' thermal-performances is necessary to predict comfort of the occupants in buildings and to identify alternate cooling control-systems for achieving better indoor thermal environments. An analysis and prediction of thermal-comfort using DesignBuilder, based on the state-of-the-art building performance simulation software EnergyPlus, is carried out in an air-conditioned multi-storeyed building in the city of Rockhampton in Central Queensland, Australia. Rockhampton is located in a hot humid-region; therefore, indoor thermal-comfort is strongly affected by the outdoor climate. This study evaluates the actual thermal conditions of the Information Technology Division (ITD) building at Central Queensland University during winter and summer seasons and identifies the thermal comfort level of the occupants using low-energy cooling technologies namely, chilled ceiling (CC), economiser usages and pre-cooling. The Fanger comfort-model, Pierce two-node model and KSU two-node model were used to predict thermal performance of the building. A sophisticated building-analysis tool was integrated with the thermal comfort models for determining appropriate cooling-technologies for the occupants to be thermally comfortable while achieving sufficient energy savings. This study compares the predicted mean-vote (PMV) index on a seven-point thermal-sensation scale, calculated using the effective temperature and relative humidity for those cooling techniques. Simulated results show that systems using a chilled ceiling offer the best thermal comfort for the occupants during summer and winter in subtropical climates. The validity of the simulation results was checked with measured values of temperature and humidity for typical days in both summer and winter. The predicted results show a reasonable agreement with the measured data. (author)

  6. Simulation and optimization for synthetic technology of 2-chloro-4, 6-dinitroresorcinol based on back-propagation neural network

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Back-propagation neural network was applied to predict and optimize the synthetic technology of 2-chloro-4,6-dinitroresorcinol. A model was established based on back-propagation neural network using the experimental data of homogeneous design as the training sample set and the technological parameters were optimized by it. The optimal technological parameters are as follows: the reaction time is 4h, the rewere performed and the average yield of 2-chloro-4,6-dinitroresorcinol is 96.64%, the absolute error of it with the predicted value is - 1.07 %.

  7. Experimental teaching of network interconnection based on simulation software technology%基于仿真软件技术的网络互联实验教学

    Institute of Scientific and Technical Information of China (English)

    邬欢欢

    2014-01-01

    结合课程实验教学的现状,引入仿真软件完善教学效果,介绍了仿真软件的优势及在实验教学中的具体应用。通过Packet Tracer模拟器对交换机VLAN配置实验进行仿真,结果表明,仿真实验教学有利于提高学生的实践技能,保证教学质量,是传统实验教学的有益补充。%According to the current situation of experimental teaching, inducting simulation software technology to improve the teaching effect, recounting the advantages and application of simulation software in experiment teaching. This paper utilizes the Packet Tracer simulator to simulate the switch VLAN configuration experiment, the results suggest that the simulation experiment teaching would be propitious to enhance students practical skills, ensure the quality of teaching, which is a beneifcial supplementary means of the traditional experiment teaching.

  8. Prognostic Relevance of Objective Response According to EASL Criteria and mRECIST Criteria in Hepatocellular Carcinoma Patients Treated with Loco-Regional Therapies: A Literature-Based Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Bruno Vincenzi

    Full Text Available The European Association for the Study of the Liver (EASL criteria and the modified Response Evaluation Criteria in Solid Tumors (mRECIST are currently adopted to evaluate radiological response in patients affected by HCC and treated with loco-regional procedures. Several studies explored the validity of these measurements in predicting survival but definitive data are still lacking.To conduct a systematic review of studies exploring mRECIST and EASL criteria usefulness in predictive radiological response in HCC undergoing loco-regional therapies and their validity in predicting survival.A comprehensive search of the literature was performed in electronic databases EMBASE, MEDLINE, COCHRANE LIBRARY, ASCO conferences and EASL conferences up to June 10, 2014. Our overall search strategy included terms for HCC, mRECIST, and EASL. Loco-regional procedures included transarterial embolization (TAE, transarterial chemoembolization (TACE and cryoablation. Inter-method agreement between EASL and mRECIST was assessed using the k coefficient. For each criteria, overall survival was described in responders vs. non-responders patients, considering all target lesions response.Among 18 initially found publications, 7 reports including 1357 patients were considered eligible. All studies were published as full-text articles. Proportion of responders according to mRECIST and EASL criteria was 62.4% and 61.3%, respectively. In the pooled population, 1286 agreements were observed between the two methods (kappa statistics 0.928, 95% confidence interval 0.912-0.944. HR for overall survival (responders versus non responders according to mRECIST and EASL was 0.39 (95% confidence interval 0.26-0.61, p<0.0001 and 0.38 (95% confidence interval 0.24-0.61, p<0.0001, respectively.In this literature-based meta-analysis, mRECIST and EASL criteria showed very good concordance in HCC patients undergoing loco-regional treatments. Objective response according to both criteria

  9. Mapeamento de locos de características quantitativas associados à composição de carcaça, no cromossomo seis de suíno

    OpenAIRE

    A.V. Pires; P.S. Lopes; GUIMARÃES, S. E. F.; C.T. Guimarães; J.O. Peixoto

    2008-01-01

    Uma população de suínos, composta de 550 animais F2, foi produzida a partir do intercruzamento da geração F1, obtida pelo cruzamento divergente de dois machos da raça nativa brasileira Piau com 18 fêmeas comerciais. O objetivo do trabalho foi mapear locos de características quantitativas (QTL) associados a cortes de carcaça. Os animais foram genotipados para 13 marcadores microssatélites, distribuídos no cromossomo 6 de suínos. As características avaliadas foram: peso total do pernil, peso do...

  10. Development of the fabrication technology of the simulated fuel-I, 15,000MWd/tU

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Kweon Ho; Kim, D. J.; Kim, H. S.; Lee, J. W.; Yang, M. S

    2001-04-01

    It is important to get basic data to analysis physical properties, behavior in reactor and performance of the DUPIC fuel because physical properties, fission gas release, grain growth and et al. of the DUPIC fuel is different from the commercial UO2 fuel. But what directly measures physical properties et al. of DUPIC fuel being resinterred simulated spent fuel through OREOX process is very difficult in laboratory owing to its high level radiation. Then fabrication of simulated DUPIC fuel is needed to measure its properties. In this study, the sintering characterization of wet milled powder for 24 hours to fabricate 15,000MWd/tU equivalent burnup simulated fuel.

  11. Acoustic Performance of Novel Fan Noise Reduction Technologies for a High Bypass Model Turbofan at Simulated Flights Conditions

    Science.gov (United States)

    Elliott, David M.; Woodward, Richard P.; Podboy, Gary G.

    2010-01-01

    Two novel fan noise reduction technologies, over the rotor acoustic treatment and soft stator vane technologies, were tested in an ultra-high bypass ratio turbofan model in the NASA Glenn Research Center s 9- by 15-Foot Low-Speed Wind Tunnel. The performance of these technologies was compared to that of the baseline fan configuration, which did not have these technologies. Sideline acoustic data and hot film flow data were acquired and are used to determine the effectiveness of the various treatments. The material used for the over the rotor treatment was foam metal and two different types were used. The soft stator vanes had several internal cavities tuned to target certain frequencies. In order to accommodate the cavities it was necessary to use a cut-on stator to demonstrate the soft vane concept.

  12. Using GTO-Velo to Facilitate Communication and Sharing of Simulation Results in Support of the Geothermal Technologies Office Code Comparison Study

    Energy Technology Data Exchange (ETDEWEB)

    White, Signe K.; Purohit, Sumit; Boyd, Lauren W.

    2015-01-26

    The Geothermal Technologies Office Code Comparison Study (GTO-CCS) aims to support the DOE Geothermal Technologies Office in organizing and executing a model comparison activity. This project is directed at testing, diagnosing differences, and demonstrating modeling capabilities of a worldwide collection of numerical simulators for evaluating geothermal technologies. Teams of researchers are collaborating in this code comparison effort, and it is important to be able to share results in a forum where technical discussions can easily take place without requiring teams to travel to a common location. Pacific Northwest National Laboratory has developed an open-source, flexible framework called Velo that provides a knowledge management infrastructure and tools to support modeling and simulation for a variety of types of projects in a number of scientific domains. GTO-Velo is a customized version of the Velo Framework that is being used as the collaborative tool in support of the GTO-CCS project. Velo is designed around a novel integration of a collaborative Web-based environment and a scalable enterprise Content Management System (CMS). The underlying framework provides a flexible and unstructured data storage system that allows for easy upload of files that can be in any format. Data files are organized in hierarchical folders and each folder and each file has a corresponding wiki page for metadata. The user interacts with Velo through a web browser based wiki technology, providing the benefit of familiarity and ease of use. High-level folders have been defined in GTO-Velo for the benchmark problem descriptions, descriptions of simulator/code capabilities, a project notebook, and folders for participating teams. Each team has a subfolder with write access limited only to the team members, where they can upload their simulation results. The GTO-CCS participants are charged with defining the benchmark problems for the study, and as each GTO-CCS Benchmark problem is

  13. An interactive physics-based unmanned ground vehicle simulator leveraging open source gaming technology: progress in the development and application of the virtual autonomous navigation environment (VANE) desktop

    Science.gov (United States)

    Rohde, Mitchell M.; Crawford, Justin; Toschlog, Matthew; Iagnemma, Karl D.; Kewlani, Guarav; Cummins, Christopher L.; Jones, Randolph A.; Horner, David A.

    2009-05-01

    It is widely recognized that simulation is pivotal to vehicle development, whether manned or unmanned. There are few dedicated choices, however, for those wishing to perform realistic, end-to-end simulations of unmanned ground vehicles (UGVs). The Virtual Autonomous Navigation Environment (VANE), under development by US Army Engineer Research and Development Center (ERDC), provides such capabilities but utilizes a High Performance Computing (HPC) Computational Testbed (CTB) and is not intended for on-line, real-time performance. A product of the VANE HPC research is a real-time desktop simulation application under development by the authors that provides a portal into the HPC environment as well as interaction with wider-scope semi-automated force simulations (e.g. OneSAF). This VANE desktop application, dubbed the Autonomous Navigation Virtual Environment Laboratory (ANVEL), enables analysis and testing of autonomous vehicle dynamics and terrain/obstacle interaction in real-time with the capability to interact within the HPC constructive geo-environmental CTB for high fidelity sensor evaluations. ANVEL leverages rigorous physics-based vehicle and vehicle-terrain interaction models in conjunction with high-quality, multimedia visualization techniques to form an intuitive, accurate engineering tool. The system provides an adaptable and customizable simulation platform that allows developers a controlled, repeatable testbed for advanced simulations. ANVEL leverages several key technologies not common to traditional engineering simulators, including techniques from the commercial video-game industry. These enable ANVEL to run on inexpensive commercial, off-the-shelf (COTS) hardware. In this paper, the authors describe key aspects of ANVEL and its development, as well as several initial applications of the system.

  14. Fundamental Research on Percussion Drilling: Improved rock mechanics analysis, advanced simulation technology, and full-scale laboratory investigations

    Energy Technology Data Exchange (ETDEWEB)

    Michael S. Bruno

    2005-12-31

    This report summarizes the research efforts on the DOE supported research project Percussion Drilling (DE-FC26-03NT41999), which is to significantly advance the fundamental understandings of the physical mechanisms involved in combined percussion and rotary drilling, and thereby facilitate more efficient and lower cost drilling and exploration of hard-rock reservoirs. The project has been divided into multiple tasks: literature reviews, analytical and numerical modeling, full scale laboratory testing and model validation, and final report delivery. Literature reviews document the history, pros and cons, and rock failure physics of percussion drilling in oil and gas industries. Based on the current understandings, a conceptual drilling model is proposed for modeling efforts. Both analytical and numerical approaches are deployed to investigate drilling processes such as drillbit penetration with compression, rotation and percussion, rock response with stress propagation, damage accumulation and failure, and debris transportation inside the annulus after disintegrated from rock. For rock mechanics modeling, a dynamic numerical tool has been developed to describe rock damage and failure, including rock crushing by compressive bit load, rock fracturing by both shearing and tensile forces, and rock weakening by repetitive compression-tension loading. Besides multiple failure criteria, the tool also includes a damping algorithm to dissipate oscillation energy and a fatigue/damage algorithm to update rock properties during each impact. From the model, Rate of Penetration (ROP) and rock failure history can be estimated. For cuttings transport in annulus, a 3D numerical particle flowing model has been developed with aid of analytical approaches. The tool can simulate cuttings movement at particle scale under laminar or turbulent fluid flow conditions and evaluate the efficiency of cutting removal. To calibrate the modeling efforts, a series of full-scale fluid hammer

  15. Technologies for Bionic Simulation of Osteocyte Microenvironment%骨细胞微环境仿生模拟技术

    Institute of Scientific and Technical Information of China (English)

    任丽; 续惠云; 骞爱荣; 商澎

    2014-01-01

    mechanical stimulations.The microenvironment surrounding osteocyte is therefore of crucial importance to both elucidating the mechanism of mechanical perception and discovery of new biological functions.However,the complicated lacuna-canalicular network surrounded by rigid bone matrix makes the study of osteocyte in vivo technically difficult.It can be of great significance to reconstruct bionic microenvironment in vitro for further revealing the functions of osteocyte.The systematic introduction of structural,biochemical and mechanical microenvironment surrounding osteocyte was presented here,and the recent technologies for simulation of bionic microenvironment in vitro were also reviewed.This review will provide a useful reference for researchers who are interested in osteology,tissue engineering and regenerative medicine.

  16. Simulating future wheat yield under climate change, carbon dioxide enrichment and technology improvement in Iran. Case study: Azarbaijan region

    Energy Technology Data Exchange (ETDEWEB)

    Mansouri, H.; Raei, Y.; Zaeim, A.N.

    2015-07-01

    Climate change and technology development can affect crop productivity in future conditions. Precise estimation of crops yield change as affected by climate and technology in the future is an effective approach for management strategies. The aim of this study was to estimate the impacts of climate change, technology improvement, CO2 enrichment, and overall impacts on wheat yield under future conditions. Wheat yield was projected for three future time periods (2020, 2050 and 2080) compared to baseline year (2011) under two scenarios of IPCC Special Report on Emission Scenarios (SRES) including SRES-A2 as regional economic scenario and SRES-B1 as global environmental scenario in Azarbaijan region (NW of Iran). A linear regression model, describing the relationship between wheat yield and historical year, was developed to investigate technology development effect. The decision support system for agro-technology transfer (DSSAT4.5) was used to evaluate the influence of climate change on wheat yield. The most positive effects were found for wheat yield as affected by technology in all studied regions. Under future climate change, the SRES projected a decrease in yield, especially in West Azarbaijan region. When the effects of elevated CO2 were considered, all regions resulted to increase in wheat yield. Considering all components effect in comparison with baseline (2011), yield increase would range from 5% to 38% across all times, scenarios and regions. According to our findings, it seems that we may expect a higher yield of wheat in NW Iran in the future if technology development continues as well as past years. (Author)

  17. Safety Skills Simulation Training System Based on MMORPG and Visual Simulation Technology%基于MMORPG和视景仿真技术的安全技能仿真培训系统

    Institute of Scientific and Technical Information of China (English)

    杨萍

    2012-01-01

    In order to improve the electric safety skills training effect, MMORPG and visual simulation technology is applied to electric power safety skills simulation training system. It can realize the scene full three -dimensional simulation and flexible setup. In high simulation scenes, the power on—site personnel safety skill training has a positive effect on improving the training of safety consciousness and enhancing their safety skills level.%为提高电力安全技能培训效果,将MMORPG和视景仿真技术应用到电力安全技能仿真培训系统中,可以实现现场场景的全三维仿真及灵活设置.在高仿真度的场景中对电力现场作业人员进行安全技能培训,对增强培训人员的安全意识及提升他们的安全技能水平有着积极的作用.

  18. Development of health inter-professional telemedicine practice through simulation scenario training with students of physiotherapy-, occupational therapy-, medical laboratory technology, and nursing education

    DEFF Research Database (Denmark)

    Nortvig, Anne-Mette; Vestergaard, Kitt

    . Aims: The purpose of the project was • to develop practice oriented competences related to telemedicine in an inter-professional and a cross-sectoral context among health professional students of physiotherapy-, occupational therapy-, medical laboratory technology-, and nursing education. • to motivate...... and retain male students by the use of simulation training that involves technology. Methodology: The project was settled as a cross-professional telemedicine course on health educations. Nursing students (N=20) and physiotherapy students (N=34) participated actively and the scenarios were filmed and enacted...... and qualitative interviews. Recordings, field notes, memos and observations of students and lecturers were used as empirical material for follow-up research. Data were analyzed in order to categorize the theoretical perspectives relating to learning and motivation. Results: Evaluations and follow-up research...

  19. The role of technology in different framings of scenario-based simulation in nursing education and the impact on design for learning

    DEFF Research Database (Denmark)

    Nortvig, Anne-Mette; Jørnø, Rasmus Leth; Gundersen, Peter

    2013-01-01

    Scenarios for simulation in nurse education are often designed around specialized technological equipment such as full-sized programmable manikins in order to achieve a high level of fidelity and credibility. The scripted scenarios are performed or played out by students as part of their training...... (-) that the scenario is not real. Time-outs where the student steps out of character and back-stage communication in between performances are considered part of the design. These pauses are not only opportunities for reflection but can be used to discuss alternative courses of action with peers, recall information...... opportunities for reflection on action. In such designs technology withdraws into the background as part of an evaluation of how realistic the scenario is deemed. The emphasis is on evaluation of the performance. In this paper we would first like to offer an analysis of the above approach as evaluative as we...

  20. Development of health inter-professional telemedicine practice through simulation scenario training with students of physiotherapy-, occupational therapy-, medical laboratory technology-, and nursing education

    DEFF Research Database (Denmark)

    Nortvig, Anne-Mette; Vestergaard*, Kitt

    2014-01-01

    must take place in an inter-professional context. Aims: The purpose of the project was •to develop practice oriented competences related to telemedicine in an inter-professional and a cross-sectoral context among health professional students of physiotherapy-, occupational therapy-, medical laboratory...... and motivation. Results: Evaluations and follow-up research showed that students developed competences equivalent to novice level through simulation training (3). The project gave rise to wide project on Occupational Therapy education and medical laboratory technology education too. Follow-up research concludes...

  1. Modeling rational, psychological, and social behavior toward diffusion of new technology using agent-based simulation: the case of the public utility jeepney (PUJ) fleet in Metro Manila

    DEFF Research Database (Denmark)

    Ahanchian, Mohammad; Biona, Jose Bienvenido Manuel

    2017-01-01

    is to assist policymakers for energy and environmental policy design based on consumers’ behavior. The jeepney owners in the old public utility jeepney (PUJ) fleet in Metro Manila are chosen as case study to prove the applicability of the model. The results show that rational, psychological, and social...... configuration affect diffusion of innovation. This study presents an agent-based model (ABM) to simulate the rational decision-making, psychological behavior, and social interaction of people to explore their reaction to policy scenarios toward adopting technological changes over time. The aim of model...

  2. Diffusion of the biogas technology into Switzerland: a GIS-based multiagent simulation; Diffusion der Biogastechnologie in der Schweiz: eine GIS-basierte Multiagenten-Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, Christian [Campana und Schott Realisierungsmanagement Schweiz AG, Zuerich (Switzerland); Madlener, Reinhard [Lehrstuhl fuer Wirtschaftswissenschaften insb. Energieoekonomik, Inst. for Future Energy Consumer Needs and Behavior (FCN), Fakultaet fuer Wirtschaftswissenschaften/E.ON Energy Research Center, RWTH Aachen (Germany)

    2008-12-15

    In this article we introduce a GIS-based multi-agent simulation model. It is used to study the spatial diffusion dynamics of agricultural biogas plants in Switzerland, which lags markedly behind those in the neighboring countries Austria and Germany. The investigation concentrates in particular on the impacts of economic factors and of locally available resources on the diffusion process. The model considers three different types of plants (100 kW{sub el}, 200 kW{sub el}, 1 MW{sub el}). The results show that feed-in tariffs, cosubstrate prices and the revenues from heat sales are critical parameters. They indicate further that the present promotion policy fosters smaller plants, whereas larger plants are preferred only in few areas with high substrate densities. Finally, we find evidence that increased heat sales can significantly raise diffusion dynamics, and that the higher feed-in tariffs planned in Switzerland could actually overcompensate deteriorating cosubstrate prices. (orig.)

  3. Research and implementation of RF signal polarization simulation technology%射频信号极化模拟技术研究与实现

    Institute of Scientific and Technical Information of China (English)

    尹彬; 王帅雷; 陈振兴

    2016-01-01

    Polarization information plays a more and more important role in radar target detection and rec‐ognition .Simulation of RF signal polarization technology uses dual‐polarized broadband antenna to produce axial ratio adjustable , rotation adjustable , angle adjustable plane wave which can simulate radar signal polarization characteristics .RF signal polarization simulator can realize local control ,remote control ,data playback and automatic calibration .It can realize the simulation of line polarization ,circular polarization and elliptical polarization in high accuracy and wide band for engineering application .%极化信息在雷达目标检测和识别中起到越来越重要的作用。射频信号极化模拟技术利用正交双极化宽带天线产生轴比可调、旋向可调、倾角可调的平面波,模拟雷达信号极化特性。极化模拟装置具有本地控制、远程控制、外场数据回放和自动化校准等功能,实现了线极化、圆极化和椭圆极化等高精度、大带宽极化状态的快速模拟,可满足工程应用要求。

  4. Method of simulation of low dose rate for total dose effect in 0.18 {mu}m CMOS technology

    Energy Technology Data Exchange (ETDEWEB)

    He Baoping; Yao Zhibin; Guo Hongxia; Luo Yinhong; Zhang Fengqi; Wang Yuanming; Zhang Keying, E-mail: baopinghe@126.co [Northwest Institute of Nuclear Technology, Xi' an 710613 (China)

    2009-07-15

    Three methods for simulating low dose rate irradiation are presented and experimentally verified by using 0.18 {mu}m CMOS transistors. The results show that it is the best way to use a series of high dose rate irradiations, with 100 {sup 0}C annealing steps in-between irradiation steps, to simulate a continuous low dose rate irradiation. This approach can reduce the low dose rate testing time by as much as a factor of 45 with respect to the actual 0.5 rad (Si)/s dose rate irradiation. The procedure also provides detailed information on the behavior of the test devices in a low dose rate environment.

  5. Herança e desequilíbrio de ligação em sete locos isoenzimáticos de Cecropia pachystachya. Inheritance and linkage disequilibrium in sevem isozymes loci of Cecropia pachystachya.

    Directory of Open Access Journals (Sweden)

    Luciano Arruda RIBAS

    2004-12-01

    Full Text Available Seis sistemas enzimáticos (ACP,G6PDH, IDH, PGI, PGM e SKDH, codificandosete locos polimórficos (Acp-3, G6pdh-1, Idh-1,Pgi-2, Pgm-1, Pgm-2 e Skdh-1, foram investigadospara a herança e desequilíbrio de ligação emCecropia pachystachya Trec. A herança mendelianafoi confirmada para todos os locos avaliados.Desvios significativos da razão de segregaçãoesperada 1:1 foram detectados apenas em umaprogênies de árvore heterozigótica. O desequilíbriode ligação foi examinado para 21 pares de locosisoenzimáticos, não sendo detectados desequilíbriosentre nenhum deles e, assim, estes podem serutilizados em subseqüentes estudos do sistemade reprodução, diversidade e estrutura genética deC. pachystachya.

  6. Utility of second-look examinations in the management of a new hypermetabolic lesion detected by fluorodeoxyglucose positron emission tomography/CT for diagnosis of loco-regional recurrence in patients with breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jin Young; Cho, Kyu Ran; Park, Eun Kyung; Seo, Bo Kyoung; Woo, Ok Hee; Song, Sung Eun; Oh, Yu Whan; Bae, Jeong Won [Korea University College of Medicine, Seoul (Korea, Republic of)

    2014-02-15

    To investigate the clinical significance of a new hypermetabolic lesion detected by fluorodeoxyglucose positron emission tomography/CT (FDG-PET/CT) as well as the utility of second-look examinations to evaluate loco-regional recurrence of breast cancer. Our database revealed 922 breast cancer patients who underwent surgery from January 2008 to July 2011. We included 20 patients with negative findings on routine follow-up but with new hypermetabolic lesions on FDG-PET/CT. All underwent second-look examination [breast ultrasound (US) = 14, chest CT scan = 6]. A total of 17 cases were pathologically verified and 3 were diagnosed with follow-up imaging. The locations were in the axillae (n = 7), breast (n = 6), chest wall (n = 3), cervical/supraclavicular (n = 3), and internal mammary (n = 1). Of the 20 hypermetabolic lesions, 10 were pathologically confirmed malignancies. Of the 14 patients who had undergone US, 7 had suspicious findings and 5 were confirmed as malignancies. Of a total of 6 patients who had undergone CT scans, 5 had suspicious findings and all turned out to be malignancies. The positive predictive value of the second-look examination was 83.3% (10/12). Second-look examination and pathologic confirmation should be performed for newly appearing hypermetabolic lesions on FDG-PET/CT in order to exclude loco-regional recurrence in breast cancer patients.

  7. 库存系统仿真技术及应用%Inventory System Simulation Technology and its Application

    Institute of Scientific and Technical Information of China (English)

    赵斌; 石伟; 张晓萍; 陈昌祥

    2003-01-01

    对库存仿真系统的理论和应用进行研究,介绍了我们开发的专用于库存系统仿真的软件ISim(Inventory System Simulation Software Package),举例说明了仿真系统在库存控制中的应用.

  8. III-V tri-gate quantum well MOSFET: Quantum ballistic simulation study for 10 nm technology and beyond

    Science.gov (United States)

    Datta, Kanak; Khosru, Quazi D. M.

    2016-04-01

    In this work, quantum ballistic simulation study of a III-V tri-gate MOSFET has been presented. At the same time, effects of device parameter variation on ballistic, subthreshold and short channel performance is observed and presented. The ballistic simulation result has also been used to observe the electrostatic performance and Capacitance-Voltage characteristics of the device. With constant urge to keep in pace with Moore's law as well as aggressive scaling and device operation reaching near ballistic limit, a full quantum transport study at 10 nm gate length is necessary. Our simulation reveals an increase in device drain current with increasing channel cross-section. However short channel performance and subthreshold performance get degraded with channel cross-section increment. Increasing device cross-section lowers threshold voltage of the device. The effect of gate oxide thickness on ballistic device performance is also observed. Increase in top gate oxide thickness affects device performance only upto a certain value. The thickness of the top gate oxide however shows no apparent effect on device threshold voltage. The ballistic simulation study has been further used to extract ballistic injection velocity of the carrier and ballistic carrier mobility in the channel. The effect of device dimension and gate oxide thickness on ballistic velocity and effective carrier mobility is also presented.

  9. A Comparison Study of Augmented Reality versus Interactive Simulation Technology to Support Student Learning of a Socio-Scientific Issue

    Science.gov (United States)

    Chang, Hsin-Yi; Hsu, Ying-Shao; Wu, Hsin-Kai

    2016-01-01

    We investigated the impact of an augmented reality (AR) versus interactive simulation (IS) activity incorporated in a computer learning environment to facilitate students' learning of a socio-scientific issue (SSI) on nuclear power plants and radiation pollution. We employed a quasi-experimental research design. Two classes (a total of 45…

  10. Progress of Radioactive Waste Treatment Technology:Migration Research Progress of Key Nuclides under Simulated Disposal Conditions

    Institute of Scientific and Technical Information of China (English)

    ZHOU; Duo; LONG; Hao-qi; JIANG; Tao; SONG; Zhi-xin; CHEN; Xi; BAO; Liang-jin; WANG; Bo

    2015-01-01

    Important parameters used in safety evaluation of HLW disposal repository could be provided through migration study of key nuclides under the simulated disposal conditions which is one of the key contents of deep geological disposal research of HLW.In order to clarify migration mechanism and calculate migration

  11. A review of the design and development processes of simulation for training in healthcare - A technology-centered versus a human-centered perspective.

    Science.gov (United States)

    Persson, Johanna

    2017-01-01

    This article reviews literature about simulation systems for training in healthcare regarding the prevalence of human-centered approaches in the design and development of these systems, motivated by a tradition in this field of working technology-centered. The results show that the focus on human needs and context of use is limited. It is argued that a reduction of the focus on technical advancements in favor of the needs of the users and the healthcare community, underpinned by human factors and ergonomics theory, is favorable. Due to the low number of identified articles describing or discussing human-centered approaches it is furthermore concluded that the publication culture promotes technical descriptions and summative evaluations rather than descriptions and reflections regarding the design and development processes. Shifting the focus from a technology-centered approach to a human-centered one can aid in the process of creating simulation systems for training in healthcare that are: 1) relevant to the learning objectives, 2) adapted to the needs of users, context and task, and 3) not selected based on technical or fidelity criteria.

  12. SU-E-T-222: Computational Optimization of Monte Carlo Simulation On 4D Treatment Planning Using the Cloud Computing Technology

    Energy Technology Data Exchange (ETDEWEB)

    Chow, J [Princess Margaret Cancer Center, Toronto, ON (Canada)

    2015-06-15

    Purpose: This study evaluated the efficiency of 4D lung radiation treatment planning using Monte Carlo simulation on the cloud. The EGSnrc Monte Carlo code was used in dose calculation on the 4D-CT image set. Methods: 4D lung radiation treatment plan was created by the DOSCTP linked to the cloud, based on the Amazon elastic compute cloud platform. Dose calculation was carried out by Monte Carlo simulation on the 4D-CT image set on the cloud, and results were sent to the FFD4D image deformation program for dose reconstruction. The dependence of computing time for treatment plan on the number of compute node was optimized with variations of the number of CT image set in the breathing cycle and dose reconstruction time of the FFD4D. Results: It is found that the dependence of computing time on the number of compute node was affected by the diminishing return of the number of node used in Monte Carlo simulation. Moreover, the performance of the 4D treatment planning could be optimized by using smaller than 10 compute nodes on the cloud. The effects of the number of image set and dose reconstruction time on the dependence of computing time on the number of node were not significant, as more than 15 compute nodes were used in Monte Carlo simulations. Conclusion: The issue of long computing time in 4D treatment plan, requiring Monte Carlo dose calculations in all CT image sets in the breathing cycle, can be solved using the cloud computing technology. It is concluded that the optimized number of compute node selected in simulation should be between 5 and 15, as the dependence of computing time on the number of node is significant.

  13. 装甲车辆动力性能联合仿真技术研究%Dynamical Performance Co-Simulation Technology of the Armored Vehicle

    Institute of Scientific and Technical Information of China (English)

    骆清国; 王旭东; 张更云; 龚正波; 司东亚

    2013-01-01

    The Armored vehicle is taken as the subject,based on the working process simulation theory of turbo-charged diesel,multibody system dynamic theory and co-simulation technology,the power performance simulation model was built including the power unit,driven unit,running unit and random road model.Interact with the storage of the data between different software is implemented based on Simulink platform, and dynamic performance co-simulation of the armored vehicle is realized.The model simulated the influence of the operation of the drive and the transient operation condition of the engine, and the model is validated by the experiment.%以某型装甲车辆为研究对象,基于涡轮增压柴油机工作过程数值模拟理论、多体动力学理论和联合仿真技术,建立了包括动力装置、传动装置、行动装置以及随机路面模型的整车动力性能仿真模型.采用Simulink平台实现了不同软件之间的数据交互与存储,实现了装甲车辆整车动力性能联合仿真.该模型模拟了车辆在实际行驶过程中驾驶员操作和发动机动态工况对整车动力性能的影响,并通过实车实验进行了验证,为装甲车辆动力性能研究提供了一种新方法.

  14. Application of Simulation Technology in Higher Vocational Civil Engineering Construction Technology Teaching%仿真技术在高职土木工程施工技术课程教学中的应用探索

    Institute of Scientific and Technical Information of China (English)

    朱显鸽

    2014-01-01

    土木工程施工技术是安全技术管理专业的核心专业课程,由于本课程内容丰富、量大面广,与实践紧密结合,而学生又缺乏对实物的认识与想象,故传统的以教材为主的教学方法已经不适应,经过十多年的施工技术课程教学方法探索与实践后发现应用仿真技术可以有效地解决以往施工技术学习中的弊端。%Civil Engineering Construction Technology is the core course of security technology management professional courses, as the course content is rich, wide range of large, closely integrated with practice, and students lack of real under-standing and imagination, traditional textbook-based teaching methods are not suited, after ten years of teaching techniques and construction methods exploration, the practical application of simulation techniques can be found to effectively solve the problems of construction technology learning disadvantages.

  15. A Human-Needs-Based Dynamics to Simulate Technology Policy and Its Effects on Both Business Success and Human Happiness

    Directory of Open Access Journals (Sweden)

    Jong-Yeon Lim

    2016-11-01

    Full Text Available This paper focuses on how human needs are reflected in the market and how several technological and political policies affect the market share of government-supported industries, as well as the satisfaction of human desires and consequent happiness. In this paper, we seek to understand the dynamics of consumer decision-making processes in relation to technology products in the market. In this study, we present a new marketing model based on human needs, wants, and demands, and focus on both holistic and social perspectives. We have shown that human-based policy dynamics and sustainable human happiness can be realized by stimulating national policies for consumer happiness in the human-needs-based sector, e.g., the healthcare industry.

  16. Particle-in-Cell/Test-Particle Simulations of Technological Plasmas: Sputtering Transport in Capacitive Radio Frequency Discharges

    CERN Document Server

    Trieschmann, Jan; Mussenbrock, Thomas

    2016-01-01

    The paper provides a tutorial to the conceptual layout of a self-consistently coupled Particle-In-Cell/Test-Particle model for the kinetic simulation of sputtering transport in capacitively coupled plasmas at low gas pressures. It explains when a kinetic approach is actually needed and which numerical concepts allow for the inherent nonequilibrium behavior of the charged and neutral particles. At the example of a generic sputtering discharge both the fundamentals of the applied Monte Carlo methods as well as the conceptual details in the context of the sputtering scenario are elaborated on. Finally, two in the context of sputtering transport simulations often exploited assumptions, namely on the energy distribution of impinging ions as well as on the test particle approach, are validated for the proposed example discharge.

  17. Computer Simulation Techniques for Molecular Structure of Coal for Advanced Coal Conversion Technology; Sekitan kodo henkan no tameno bunshikozo shimyureshon

    Energy Technology Data Exchange (ETDEWEB)

    Takanohashi, Toshimasa [Energy Resources Dept., Tokyo (Japan). Fundamental Research Div.; Nakamura, Kazuo [Osaka Gas Corp., Osaka (Japan). Fundamental Research Laboratories; Iino, Masashi [Tohoku University, Miyagi (Japan), Institute for Chemical Reaction Science

    1999-02-25

    Coal has complex chemical structure consisting of various bond types and the details are still not well understood. Recently, in addition to improvements of analytical techniques, molecular modeling and simulation techniques by using powerful computers and software have greatly developed and it has become possible to apply them to complex structure such as coal. Knowledge of coal's molecular structure is important for the understanding of various coal properties and reactivities under several conditions. In this paper, a new tool, i.e., molecular modeling technique of coal's macromolecular structure and dynamic simulation of coal properties, is introduced and the future applications of this technique will be outlined. (author)

  18. A Guide for Developing Human-Robot Interaction Experiments in the Robotic Interactive Visualization and Experimentation Technology (RIVET) Simulation

    Science.gov (United States)

    2016-05-01

    camera control for remote exploration. In: Proceedings of ACM CHI 2004 Conference on Human Factors in Computing Systems; 2004 Apr 24–29; Vienna...Austria. New York (NY): ACM ; c2004. p. 511–517. Kunkler K. The role of medical simulation: an overview. The International Journal of Medical Robotics and...Schreckenghost D. Survey of metrics for human-robot interaction. In: Proceedings of the 8th ACM /IEEE Human-Robot Interaction Conference; HRI 2013

  19. Particle-in-Cell/Test-Particle Simulations of Technological Plasmas: Sputtering Transport in Capacitive Radio Frequency Discharges

    OpenAIRE

    Trieschmann, Jan; Schmidt, Frederik; Mussenbrock, Thomas

    2016-01-01

    The paper provides a tutorial to the conceptual layout of a self-consistently coupled Particle-In-Cell/Test-Particle model for the kinetic simulation of sputtering transport in capacitively coupled plasmas at low gas pressures. It explains when a kinetic approach is actually needed and which numerical concepts allow for the inherent nonequilibrium behavior of the charged and neutral particles. At the example of a generic sputtering discharge both the fundamentals of the applied Monte Carlo me...

  20. Morphological analysis and preoperative simulation of a double-chambered right ventricle using 3-dimensional printing technology.

    Science.gov (United States)

    Shirakawa, Takashi; Koyama, Yasushi; Mizoguchi, Hiroki; Yoshitatsu, Masao

    2016-05-01

    We present a case of a double-chambered right ventricle in adulthood, in which we tried a detailed morphological assessment and preoperative simulation using 3-dimensional (3D) heart models for improved surgical planning. Polygonal object data for the heart were constructed from computed tomography images of this patient, and transferred to a desktop 3D printer to print out models in actual size. Medical staff completed all of the work processes. Because the 3D heart models were examined by hand, observed from various viewpoints and measured by callipers with ease, we were able to create an image of the complete form of the heart. The anatomical structure of an anomalous bundle was clearly observed, and surgical approaches to the lesion were simulated accurately. During surgery, we used an incision on the pulmonary infundibulum and resected three muscular components of the stenosis. The similarity between the models and the actual heart was excellent. As a result, the operation for this rare defect was performed safely and successfully. We concluded that the custom-made model was useful for morphological analysis and preoperative simulation.

  1. 半实物仿真中的高精度激光回波模拟技术%Technology of simulation for high-precision echo laser

    Institute of Scientific and Technical Information of China (English)

    高阳; 雷杰; 虞红; 刘扬; 刘继桥

    2012-01-01

    Along with the expansion of application demand, the new generation of guiding system must be able to obtain rich information in the detection process, including angle and distance information. Therefore, laser ranging technology becomes a hot spot in the field of guiding field. In order to provide the simulation experimental conditions for laser ranging technology, a lot of works on laser echo simulation were done. In this paper, the development of the echo simulation system was described, which had the characteristic of angle and distance measurement for the laser ranging system. This system was named as laser echo simulator. The simulator could give the proper echo signal with a corresponding delay after receiving the trigger signal from the detection system. The echo characteristic and delay control capacity were analyzed. The hardware-in-the -loop system design was presented to verify the performance of laser ranging system. The experimental results indicate the feasibility of the system.%过去寻的探测系统只获得目标的二维信息:俯仰角度信息和偏航角度信息.在战场环境日益复杂的今天,目标和导弹的速度都越来越快,飞行控制的时间也越来越短.由于这些变化,过去的探测系统的能力渐渐不能满足现代作战需求.随着应用需求的不断扩展,需要在制导过程中能够获得更加丰富的目标位置信息,不仅是方位角度信息,还应包括距离信息.于是,激光测距技术成为制导领域的一个研究热点.针对激光测距系统的测距功能和测角功能研制了一套回波模拟系统,称之为激光回波模拟器.对验证激光测距系统性能的半实物仿真系统进行了系统设计,并实验验证了这套系统的可行性.

  2. A Novel Methodology of Simulation and Realization of Various OPAMP Topologies in 0.18μm CMOS Technology Using MATLAB

    Directory of Open Access Journals (Sweden)

    E.Srinivas

    2015-10-01

    Full Text Available This paper presents a novel methodology of simulation and realization of a various Op-amp topologies, such as two-stage, telescopic and folded cascade are discussed in this paper. The aim of the present work is the development of a tool box which contains the Matlab code to allow automated synthesis of Analog circuits. This tool box is used to find the transistor dimensions (i.e.., width and length in order to obtain the performance specifications of a two stage op-amp, telescopic op-amp and folded cascode op-amp. In This paper five parameters are considered such as Gain (G, Unity gain frequency (UGF, Phase margin (PM, Slew rate (SR and Power consumption(P. The designs have been simulated by using 0.18µm CMOS technology with a supply voltage of ±1.8v.Finally, a good agreement is observed between the Matlab based tool box and electrical simulation.

  3. Monte Carlo simulations of molecular gas flow: some applications in accelerator vacuum technology using a versatile personal computer program

    Energy Technology Data Exchange (ETDEWEB)

    Pace, A.; Poncet, A. (European Organization for Nuclear Research, Geneva (Switzerland))

    1990-01-01

    The Monte Carlo technique has been used extensively in the past to solve the problem of molecular flow through vacuum pipes or structures with specific boundary conditions for which analytical or even approximate solutions do not exist. Starting from a specific program written in 1975, the idea germinated over the years to produce handy, rather general, problem solving applications capable of running efficiently on modern microcomputers, mainly for ease of transportability and interactivity. Here, the latest version is described. The capabilities and limitations of these tools are presented through a few practical cases of conductance and pumping speed calculations pertinent to accelerator vacuum technology. (author).

  4. Simulation of flow-field interior dust removal system at a transit point and the overall technology of dust removal

    Institute of Scientific and Technical Information of China (English)

    GE Shao-cheng; SHAO Liang-shan

    2008-01-01

    In order to make a reasonable dry-type dust removal plan of the coal transit spot in a coal washery, it is essential to install the dust removal fan and guide chute. By means of the numerical simulation, the pollution mechanism at a transit point and the flow-field interior dust removal system had been analyzed. The result shows that the dust pollution at transit spot is mainly cased by the joint effort of induced airflow and shock-wave. With the appropriate dust removal fan and the guide chute, will effectively eliminate the positive pressure by gave rise to by the impact of falling coal, also avoid the secondary pollution.

  5. Contribution of the Computer Technologies in the Teaching of Physics: Critical Review and Conception of an Interactive Simulation Software

    Directory of Open Access Journals (Sweden)

    Louis Trudel

    2013-08-01

    Full Text Available In the present research, we will synthesize the main research results about the development of interactive computer environments for physics teaching and learning. We will see that few types of software propose environments that take into account the user's erroneous representations in order to make him become aware of his mistakes. The majority of these softwares present modelling activities that are restricted to the automatic collection of experimental data and their analysis under graphical form. As a consequence, we will present the design of computer environments for the learning of the phenomenona of absorption and diffusion of light which will take into account the user's initial representations. The design of these environments is divided in five steps: (1 diagnostic of the user’s initial representations; (2 confrontation of the user’s initial representations by the simulation; (3 reconstruction by the user of his representations following the completion by the user of the simulation; (4 reconstruction of the user’s representations following the presentation by the software of scientific information related to the case studied and (5 assessment of the current state of understanding of the user by the software.

  6. 基于VLD技术的MCT器件仿真分析%Simulation and Analysis of MCT Device Based on VLD Technology

    Institute of Scientific and Technical Information of China (English)

    阮建新; 陈万军; 孙瑞泽; 彭朝飞; 张波

    2014-01-01

    针对在脉冲功率领域有一定应用的栅控晶闸管(MCT)器件,提出了一种基于VLD(横向变掺杂)技术的MCT(VMCT)器件新工艺并通过仿真比较出新工艺的优势。VLD技术是指通过调整掩模版窗口的大小调节杂质掺杂浓度,进而优化MCT中NPN晶体管的电流放大系数a,通过仿真确定了新工艺的杂质注入剂量。仿真结果表明采用新工艺的VMCT器件比采用常规工艺MCT (CMCT)电流能力更强,是CMCT的2倍;和CMCT相比,VMCT器件的耐压和关断电压都保持不变,但是VMCT在工艺流程中比MCT节省一张掩模版。%MOS controlled thyristor (MCT) which is used in pulsed power field is investigated by numerical simulation tool in this paper. A new process based on VLD(variable lateral doping) technology for MCT is proposed and its advantages are also found by simulation. Current amplification factor a of NPN transistor in MCT is optimized by adjust the size of mask and the dose of impurity implantation.The dose of impurity implantation is identified by simulation.The simulation results indicate that the current ability of conventional MOS controlled thyristor (CMCT) is only half of the VLD MOS controlled thyristor (VMCT). The breakdown voltage and turn off voltage of VMCT are the same as CMCT.However, compared with CMCT, a mask is saved in the VMCT process.

  7. 基于 QEMU 的外部总线仿真技术%External Bus Simulation Technology Based on QEMU

    Institute of Scientific and Technical Information of China (English)

    胡国卿; 邵培南; 陈磊; 李翔

    2014-01-01

    The communication connection among subsystems of the integrated embedded systems is achieved by an external bus. In order to solve interface test problems of the integrated embedded system, integrated embedded systems are simulated by embedded systems virtual machines which create external bus simulation modules. And the communication among virtual machines is achieved by configuring connections of these modules. This technology presents an external bus simulation structure based on Ethernet communication, and takes Controllers Area Network(CAN) bus simulation as an example. It establishes shared memory for bus device interface reading and writing data and achieves the data exchange between simulation node modules via configurations of internal bus on QEMU which is a system virtual machine, registrations of external bus devices, organizations of bus protocol packets and sending and receiving packets through the network, so as to achieve the data communication capabilities of simulation bus.%综合嵌入式系统通过外部总线实现各个子系统之间的通信连接。为解决综合嵌入式系统的接口测试问题,采用系统虚拟机仿真综合嵌入式系统的连接方式,通过在虚拟机中创建外部总线仿真模块,配置仿真模块的连接,从而实现虚拟机之间的通信。提出一种基于以太网通信的外部总线仿真结构,以 CAN 总线仿真为例,在全系统虚拟机 QEMU 的内部总线上配置与注册外部总线设备,为读写总线设备数据的接口建立共享内存,组织总线协议报文。实验结果表明,通过网络收发报文,可实现总线仿真节点模块之间的数据交换,从而达到仿真总线的数据通信功能。

  8. 烟气-蒸汽辅助重力泄油模拟技术%Numerical simulation technology of flue gas-steam assisted gravity drainage

    Institute of Scientific and Technical Information of China (English)

    林日亿; 李魏; 李兆敏; 杨立强; 杨建平

    2012-01-01

    采用加拿大CMG软件公司的CMG-STARS模拟器,对烟气-蒸汽辅助重力泄油技术中烟气在蒸汽腔中的运移规律进行数值模拟.研究烟气注入后蒸汽腔的扩展速度及形态变化规律,分析含油饱和度、黏度、压力、温度的变化规律.在优化的注入参数下,对烟气-蒸汽辅助重力泄油和常规蒸汽辅助重力泄油(SAGD)技术的开发效果进行对比.研究结果表明:优化的蒸汽注入温度为280 ℃、注入速度为150 m3/d、烟气与蒸汽比为1.0.在优化的注入参数下,烟气-蒸汽辅助重力泄油比SAGD的累积采油量提高2.0 kt,采收率提高7%,油气比增加0.7%.烟气-蒸汽辅助重力泄油技术的开发效果更好.%By using the CMG-STARS simulator, the migration laws of flue gas in the steam chamber at flue gas-steam assisted gravity drainage technology were researched. The speed of the steam chamber expanding and the variation of the shape of the steam chamber were studied after flue gas injected. The change rules of oil saturation, viscosity, pressure and temperature were analyzed. The injection parameters of flue gas were optimized by reservoir numerical simulation. With the optimized injection parameters, the development effects of flue gas-steam assisted gravity drainage technology and conventional SAGD were compared. The results show that the optimized steam injection temperature is 280℃ , the injection rate is 150 m /d, and the flue gas and steam ratio is 1.0. With the optimized injection parameters, the cumulative oil production increases by 2. 0 kt, and oil recovery efficiency increases by 7% using the flue gas-steam assisted gravity drainage technology compared with conventional SAGD. The development effect of flue gas-steam assisted gravity drainage technology is better.

  9. New weather depiction technology for night vision goggle (NVG) training: 3D virtual/augmented reality scene-weather-atmosphere-target simulation

    Science.gov (United States)

    Folaron, Michelle; Deacutis, Martin; Hegarty, Jennifer; Vollmerhausen, Richard; Schroeder, John; Colby, Frank P.

    2007-04-01

    US Navy and Marine Corps pilots receive Night Vision Goggle (NVG) training as part of their overall training to maintain the superiority of our forces. This training must incorporate realistic targets; backgrounds; and representative atmospheric and weather effects they may encounter under operational conditions. An approach for pilot NVG training is to use the Night Imaging and Threat Evaluation Laboratory (NITE Lab) concept. The NITE Labs utilize a 10' by 10' static terrain model equipped with both natural and cultural lighting that are used to demonstrate various illumination conditions, and visual phenomena which might be experienced when utilizing night vision goggles. With this technology, the military can safely, systematically, and reliably expose pilots to the large number of potentially dangerous environmental conditions that will be experienced in their NVG training flights. A previous SPIE presentation described our work for NAVAIR to add realistic atmospheric and weather effects to the NVG NITE Lab training facility using the NVG - WDT(Weather Depiction Technology) system (Colby, et al.). NVG -WDT consist of a high end multiprocessor server with weather simulation software, and several fixed and goggle mounted Heads Up Displays (HUDs). Atmospheric and weather effects are simulated using state-of-the-art computer codes such as the WRF (Weather Research μ Forecasting) model; and the US Air Force Research Laboratory MODTRAN radiative transport model. Imagery for a variety of natural and man-made obscurations (e.g. rain, clouds, snow, dust, smoke, chemical releases) are being calculated and injected into the scene observed through the NVG via the fixed and goggle mounted HUDs. This paper expands on the work described in the previous presentation and will describe the 3D Virtual/Augmented Reality Scene - Weather - Atmosphere - Target Simulation part of the NVG - WDT. The 3D virtual reality software is a complete simulation system to generate realistic

  10. Simulation Technology Research on HMS Based OpenGL%基于图像的头盔瞄准系统虚拟仿真技术研究

    Institute of Scientific and Technical Information of China (English)

    闫龙

    2011-01-01

    Helmet targeting technology has been used more and more in fighter aircraft and helicopters on the ground training and actual combat flight simulation. Under more and more observations, experiment and product prototype cost much money. An in - depth investigation into the mechanism of helmet - mounted sight(HMS) based on monotone photogrammetry techniques is reported, the aiming model with 4 points is analyzed in detail. Combing virtual reality with simulation technology, the platform is constructed to carry on the simulation of the HMS system,loading 3D model with OpenGL in VC development environment. The imaging process is simulated by setting project model parameters in accord with camera. The model is evaluated with experiments for practical use in aiming accurately. This article may provide help for understanding, designing and improving the HMS system in some extent.%研究飞行员头盔控制问题,头盔瞄准技术越来越多地应用于战斗机和直升机地面飞行模拟训练和实际作战.为了使目标瞄准线转为控制信号,实现目标识别的准确性,提出通过对单目视觉测量方法和四点定位模型采用图像式头盔瞄准具的系统结构及工作机理,实现定位模型方程.结合当今虚拟现实与仿真技术,设计并开发了头盔瞄准系统仿真平台.在VC开发环境中导入三维模型,调用OpenGL函数设置投影模型参数与相机标定参数一致,实现了摄像机成像的仿真过程,完成了图像式头盔瞄准系统工作过程的仿真,实验结果证明模型能够完成目标的精确定位,开发平台可为系统设计和系统综合设计提供参考依据.

  11. Large scale in-situ BOrehole and Geofluid Simulator (i.BOGS) for the development and testing of borehole technologies at reservoir conditions

    Science.gov (United States)

    Duda, Mandy; Bracke, Rolf; Stöckhert, Ferdinand; Wittig, Volker

    2017-04-01

    A fundamental problem of technological applications related to the exploration and provision of geothermal energy is the inaccessibility of subsurface processes. As a result, actual reservoir properties can only be determined using (a) indirect measurement techniques such as seismic surveys, machine feedback and geophysical borehole logging, (b) laboratory experiments capable of simulating in-situ properties, but failing to preserve temporal and spatial scales, or vice versa, and (c) numerical simulations. Moreover, technological applications related to the drilling process, the completion and cementation of a wellbore or the stimulation and exploitation of the reservoir are exposed to high pressure and temperature conditions as well as corrosive environments resulting from both, rock formation and geofluid characteristics. To address fundamental and applied questions in the context of geothermal energy provision and subsurface exploration in general one of Europe's largest geoscientific laboratory infrastructures is introduced. The in-situ Borehole and Geofluid Simulator (i.BOGS) allows to simulate quasi scale-preserving processes at reservoir conditions up to depths of 5000 m and represents a large scale pressure vessel for iso-/hydrostatic and pore pressures up to 125 MPa and temperatures from -10°C to 180°C. The autoclave can either be filled with large rock core samples (25 cm in diameter, up to 3 m length) or with fluids and technical borehole devices (e.g. pumps, sensors). The pressure vessel is equipped with an ultrasound system for active transmission and passive recording of acoustic emissions, and can be complemented by additional sensors. The i.BOGS forms the basic module for the Match.BOGS finally consisting of three modules, i.e. (A) the i.BOGS, (B) the Drill.BOGS, a drilling module to be attached to the i.BOGS capable of applying realistic torques and contact forces to a drilling device that enters the i.BOGS, and (C) the Fluid.BOGS, a geofluid

  12. LEARNERS: Interdisciplinary Learning Technology Projects Provide Visualizations and Simulations for Use of Geospatial Data in the Classroom

    Science.gov (United States)

    Farrell, N.; Hoban, S.

    2001-05-01

    The NASA Leading Educators to Applications, Research and NASA-related Educational Resources in Science (LEARNERS) initiative supports seven projects for enhancing kindergarten-to-high school science, geography, technology and mathematics education through Internet-based products derived from content on NASA's mission. Topics incorporated in LEARNERS projects include remote sensing of the Earth for agriculture and weather/climate studies, virtual exploration of remote worlds using robotics and digital imagery. Learners are engaged in inquiry or problem-based learning, often assuming the role of an expert scientist as part of an interdisciplinary science team, to study and explain practical problems using real-time NASA data. The presentation/poster will demonstrate novel uses of remote sensing data for K-12 and Post-Secondary students. This will include the use of visualizations, tools for educators, datasets, and classroom scenarios.

  13. Simulation of flow-field interior dust removal system at a transit point and the overall technology of dust removal

    Institute of Scientific and Technical Information of China (English)

    GE Shao-cheng; SHAO Liang-shan

    2008-01-01

    In order to make a reasonable dry-type dust removal plan of the coal transit spot in a coal washery,it is essential to install the dust removal fan and guide chute.Bymeans of the numerical simulation,the pollution mechanism at a transit point and the flow-field interior dust removal system had been analyzed.The result shows that the dustpollution at transit spot is mainly cased by the joint effort of induced airflow andshock-wave.With the appropriate dust removal fan and the guide chute,will effectively eliminate the positive pressure by gave rise to by the impact of falling coal,also avoid the secondary pollution.

  14. Simulation Study on PMSM Control System Based on SVPWM Technology%基于SVPWM技术的PMSM控制系统仿真研究

    Institute of Scientific and Technical Information of China (English)

    王丹; 李志军

    2012-01-01

    着重介绍了空间矢量脉宽调制技术的原理及算法,并将其成功地应用到永磁同步电机控制系统中,利用Simulink对控制方案进行了仿真.仿真结果表明:SVPWM技术应用在PMSM控制系统是可行的,同时获得了较好的动态品质.%Both principle and algorithm of the space vector pulse width modulation ( SVPWM ) were expounded and applied to the control system for permanent magnet synchronous motors. Simulating its control scheme with Simulink proves the feasibility of applying SVPWM technology in PMSM control system together with good dynamic quality.

  15. Application of OPC technology in the software about PLC virtual simulation%OPC技术在PLC虚拟仿真实验软件中的应用

    Institute of Scientific and Technical Information of China (English)

    周亚军; 曾洋; 俞武嘉

    2011-01-01

    为解决所设计的可编程逻辑控制器(PLC)虚拟仿真实验软件与PLC之间的通信问题,分析研究了OPC客户端与服务器端之间的通信机制,将OPC技术应用到仿真实验软件与PLC的通信交互中.设计了一种通用型OPC数据采集发送客户端,该客户端可连接通信现代工业控制上常用的多种类型的PLC,采用实时反馈的数据传送模式.最后以西门子PC Access服务器和S7-200PLC为平台,使用仿真软件中虚拟电梯实验对OPC客户端进行了测试,运行效果显示OPC技术很好地实现了系统的高效性和实时性.%To solve the problem of the communication between the programmable logic controller(PLC) and the PLC virtual simulation software, the communication mechanism between the OLE for process controll(OPC) client and server was analy ed. The OPC technology was applied in the connecting experimental program with PLC. Besides, a general-purpose data acquisition OPC client was designed, which can connect with many types of PLC used in the modern industrial controlling and which adopts the real-time feedback data transfer mode. Finally, the OPC client was tested by using virtual elevator experiment of simulation software based on the platform of Siemens PC access server and S7-200 PLC. The result of the test show that OPC technology can improve the efficiency and real-time performance of the system.

  16. Study and implementation on VPN technology based on network simulation platform%基于网络仿真平台的VPN技术研究与实现

    Institute of Scientific and Technical Information of China (English)

    石宏宇; 骆乐

    2011-01-01

    By analyzing existing network security technology, aiming to the information security transmission target, using VPN technology as a support, selecting Packet Tracer as network simulation platform, this paper designs and structures a corporate communications networks, making it build the virtual private network over the public networks and keep extranet remote users communicating with enterprise Intranet safely. It also proposes and implements a secure transmission network model, and also analyzes the implementation and characteristics of model systematically. Finally, it is proved that network simulation platform, economical and practical, plays an important role in the process of network designing, structuring, analysing and training.%通过分析现有的网络安全技术,针对信息安全传输的目标,利用VPN技术作为支撑,选择PacketTracer作为网络仿真平台,设计组建了一个企业通信网络,达到了在公共网络上建立虚拟专用网络,使外网远程用户能够安全地与企业内网进行通信的目标。提出并实现了一个安全传输的网络模型,并对模型的实现和特点进行了系统地分析。也通过实践证明,网络仿真平台经济实用,能在网络设计、组建、分析、实训的过程中发挥重要作用。

  17. Use of 3-dimensional printing technology and silicone modeling in surgical simulation: development and face validation in pediatric laparoscopic pyeloplasty.

    Science.gov (United States)

    Cheung, Carling L; Looi, Thomas; Lendvay, Thomas S; Drake, James M; Farhat, Walid A

    2014-01-01

    Pediatric laparoscopy poses unique training challenges owing to smaller workspaces, finer sutures used, and potentially more delicate tissues that require increased surgical dexterity when compared with adult analogs. We describe the development and face validation of a pediatric pyeloplasty simulator using a low-cost laparoscopic dry-laboratory model developed with 3-dimensional (3D) printing and silicone modeling. The organs (the kidney, renal pelvis, and ureter) were created in a 3-step process where molds were created with 3D modeling software, printed with a Spectrum Z510 3D printer, and cast with Dragon Skin 30 silicone rubber. The model was secured in a laparoscopy box trainer. A pilot study was conducted at a Canadian Urological Association meeting. A total of 24 pediatric urology fellows and 3 experienced faculty members then assessed our skills module during a minimally invasive surgery training course. Participants had 60 minutes to perform a right-side pyeloplasty using laparoscopic tools and 5-0 VICRYL suture. Face validity was demonstrated on a 5-point Likert scale. The dry-laboratory model consists of a kidney, a replaceable dilated renal pelvis and ureter with an obstructed ureteropelvic junction, and an overlying peritoneum with an inscribed fundamentals of laparoscopic surgery pattern-cutting exercise. During initial validation at the Canadian Urological Association, participants rated (out of 5) 4.75 ± 0.29 for overall impression, 4.50 ± 0.41 for realism, and 4.38 ± 0.48 for handling. During the minimally invasive surgery course, 22 of 24 fellows and all the faculty members completed the scoring. Usability was rated 4 or 5 by 14 participants (overall, 3.6 ± 1.22 by novices and 3.7 ± 0.58 by experts), indicating that they would use the model in their own training and teaching. Esthetically, the model was rated 3.5 ± 0.74 (novices) and 3.3 ± 0.58 (experts). We developed a pediatric pyeloplasty simulator by applying a low-cost reusable model

  18. Detecção de locos de características quantitativas com efeito da origem parental dos alelos nos cromossomos 1, 2 e 4 de suínos

    OpenAIRE

    Silva Filho,Miguel Inácio da

    2010-01-01

    Com o objetivo de detectar QTL com efeito da origem parental dos alelos, foram utilizados dados de uma população F2 de suínos, composta de 600 animais, obtidos a partir do cruzamento de machos Piau e fêmeas comerciais. Nos animais F2, foram avaliadas características de desempenho, carcaça, órgãos e vísceras, cortes de carcaça e qualidade de carne. Para a genotipagem de todos os animais, foram utilizados 16 locos de microssatélites distribuídos nos cromossomos 1, 2 e 4. Com o resultado da g...

  19. 虚拟仿真技术的三维LNG培训系统%LNG Technology Training Systems Based on Three-dimensional Virtual Simulation

    Institute of Scientific and Technical Information of China (English)

    马国光; 刘源海; 蒋茂琴

    2015-01-01

    Taking virtual three-dimensional simulation technology into LNG filling station staff training system, not only improve the efficiency of new employees, but also ensure the safe operation of LNG filling stations. The article describes the composition of the simulation system, designing model of each sub-module, NURBS modeling software methods and demonstrate interactive features of simulation system.The simulation system can be used for teaching and training, skills training staff to operate the new posts and accident drills and personnel rotation. Because of its vivid, lively and infectious, it can better mobilize the enthusiasm of students, improve the efficiency and quality of staff training and provide some technical support for the safe operation of LNG filling stations. Set of nature, science, flexibility in LNG simulation training system that can be better used in teaching and training related to LNG filling stations, is an effective means of improving staff skills.%将虚拟三维仿真技术引入到 LNG 加注站员工培训系统中, 不仅提高了新员工的工作效率, 还能保证LNG加注站的安全运行.文章系统的介绍了仿真系统的组成,各子模块的设计模型, NURBS软件建模的方法,演示了仿真系统的人机交互功能. 该仿真系统可用于专业教学与实习、新上岗员工操作技能培训以及在岗人员事故演练与轮训. 由于其逼真、生动、感染性好, 可更好的调动学员积极性, 提高员工培训效率和质量, 为LNG加注站的安全运行提供一定的技术保障. 集先进性、科学性、灵活性于一体的 LNG 仿真培训系统, 能更好的应用于LNG加注站相关教学与培训, 是一种有效的提高人员技术水平的手段.

  20. Virtual simulation technology for displaying vehicle ride comfort%展示车辆平顺性的虚拟仿真技术

    Institute of Scientific and Technical Information of China (English)

    李红波; 薛亮; 吴渝; 张寅奇

    2012-01-01

    虚拟现实技术是车辆平顺性仿真展示的主要方法之一.为了能更直观地展示车辆平顺性,参考了1/2七自由度车辆模型,在分析三维模型车辆振动组戍结构后构建了1/2二自由度车辆模型,并导出车辆垂向受力方程,实现了对车辆平顺性的模拟.为观测车辆平顺性仿真过程,提出“固定跟车”观测算法,通过平移和旋转变换,让摄像机视角与车辆位置相对固定并随车一起运动.实验表明,在车轮受到外力激励的情况下可以较真实地模拟模型车辆的振动状态,摄像机随车定点观测也更好地展现了仿真过程.%Virtual reality technology is one of the main methods for vehicle ride simulation. In order to show vehicle ride more directly, a vehicle model of 1/2 7 degrees is established. By analyzing vibration composition of three-dimensional vehicle model, a vehicle model of 1/2 two degrees is built. Then vehicle vertical force equation is educed, and the vehicle ride simulation is a-chieved. To observe simulation process of the vehicle ride comfort, an observation algorithm named " fixed with the car" is proposed. By translation and rotation, the camera angle and position of the vehicle are relatively fixed and it moves with the vehicle. Experimental results show that when wheels of the model vehicle are motivated by external force, the vehicle vibration state can be simulated truthfully, and the camera's fixed-point observation with the vehicle can also show the simulation better.

  1. UAS Air Traffic Controller Acceptability Study. 2; Evaluating Detect and Avoid Technology and Communication Delays in Simulation

    Science.gov (United States)

    Comstock, James R., Jr.; Ghatas, Rania W.; Consiglio, Maria C.; Chamberlain, James P.; Hoffler, Keith D.

    2015-01-01

    This study evaluated the effects of communications delays and winds on air traffic controller ratings of acceptability of horizontal miss distances (HMDs) for encounters between Unmanned Aircraft Systems (UAS) and manned aircraft in a simulation of the Dallas-Ft. Worth (DFW) airspace. Fourteen encounters per hour were staged in the presence of moderate background traffic. Seven recently retired controllers with experience at DFW served as subjects. Guidance provided to the UAS pilots for maintaining a given HMD was provided by information from Detect and Avoid (DAA) self-separation algorithms (Stratway+) displayed on the Multi-Aircraft Control System. This guidance consisted of amber "bands" on the heading scale of the UAS navigation display indicating headings that would result in a loss of well clear between the UAS and nearby traffic. Winds tested were successfully handled by the DAA algorithms and did not affect the controller acceptability ratings of the HMDs. Voice communications delays for the UAS were also tested and included one-way delay times of 0, 400, 1200, and 1800 msec. For longer communications delays, there were changes in strategy and communications flow that were observed and reported by the controllers. The aim of this work is to provide useful information for guiding future rules and regulations applicable to flying UAS in the NAS. Information from this study will also be of value to the Radio Technical Commission for Aeronautics (RTCA) Special Committee 228 - Minimum Performance Standards for UAS.

  2. Physics-based Simulation of Human Posture Using 3D Whole Body Scanning Technology for Astronaut Space Suit Evaluation

    Science.gov (United States)

    Kim, Kyu-Jung

    2005-01-01

    Over the past few years high precision three-dimensional (3D) full body laser scanners have been developed to be used as a powerful anthropometry tool for quantification of the morphology of the human body. The full body scanner can quickly extract body characteristics in non-contact fashion. It is required for the Anthropometry and Biomechanics Facility (ABF) to have capabilities for kinematics simulation of a digital human at various postures whereas the laser scanner only allows capturing a single static posture at each time. During this summer fellowship period a theoretical study has been conducted to estimate an arbitrary posture with a series of example postures through finite element (FE) approximation and found that four-point isoparametric FE approximation would result in reasonable maximum position errors less than 5%. Subsequent pilot scan experiments demonstrated that a bead marker with a nominal size of 6 mm could be used as a marker for digitizing 3-D coordinates of anatomical landmarks for further kinematic analysis. Two sessions of human subject testing were conducted for reconstruction of an arbitrary postures from a set of example postures for each joint motion for the forearm/hand complex and the whole upper extremity.

  3. EXPERIMENTS AND SIMULATIONS OF A NEW DEVELOPED FORMING TECHNOLOGY-SHEAR-EXTRUSION PROCESS OF COMPONENTS WITH BRANCHES

    Institute of Scientific and Technical Information of China (English)

    H.L. Yang; D.C. Kang; Z.L. Zhang; X.H. Piao; Z.D. Shi

    2001-01-01

    Shear-extrusion process and its forming parameters are proposed, whilst its laborsae ing characteristic is utilized to forge large-size shutoff valve body on middle-due pre ss.This new process is intended for the manufacture of large-size forged tubular components with branches on middle-due press. Experiments are carried out and proeessing parameters are obtained regarding the shear-extrusion process of a large-size shutoff valve body. Deformation and metal flow in the shear-extrnsion process are investigated. In order to verify the laborsaving characteristic of this new procss some contrastive experiments of extrusion foree are performed between shear-extrusion and upsetting-extrusion for forming tubular components with branches. Based on rigidplastic FEM a plane-strain model is established to analyze shear-extrusion process of tubular components with branches. The analysis results by 2-dimensions FEM are comparatively quite well consistent with those of experiments. Both simulated anl etperimental results show that this new forming process is feasible for forging large-size tubular components with branches on middle-due press.

  4. Today's Business Simulation Industry

    Science.gov (United States)

    Summers, Gary J.

    2004-01-01

    New technologies are transforming the business simulation industry. The technologies come from research in computational fields of science, and they endow simulations with new capabilities and qualities. These capabilities and qualities include computerized behavioral simulations, online feedback and coaching, advanced interfaces, learning on…

  5. Computational fluid dynamics assessment: Volume 1, Computer simulations of the METC (Morgantown Energy Technology Center) entrained-flow gasifier: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Celik, I.; Chattree, M.

    1988-07-01

    An assessment of the theoretical and numerical aspects of the computer code, PCGC-2, is made; and the results of the application of this code to the Morgantown Energy Technology Center (METC) advanced gasification facility entrained-flow reactor, ''the gasifier,'' are presented. PCGC-2 is a code suitable for simulating pulverized coal combustion or gasification under axisymmetric (two-dimensional) flow conditions. The governing equations for the gas and particulate phase have been reviewed. The numerical procedure and the related programming difficulties have been elucidated. A single-particle model similar to the one used in PCGC-2 has been developed, programmed, and applied to some simple situations in order to gain insight to the physics of coal particle heat-up, devolatilization, and char oxidation processes. PCGC-2 was applied to the METC entrained-flow gasifier to study numerically the flash pyrolysis of coal, and gasification of coal with steam or carbon dioxide. The results from the simulations are compared with measurements. The gas and particle residence times, particle temperature, and mass component history were also calculated and the results were analyzed. The results provide useful information for understanding the fundamentals of coal gasification and for assessment of experimental results performed using the reactor considered. 69 refs., 35 figs., 23 tabs.

  6. Assessment of analytical and experimental techniques utilized in conducting plume technology tests 575 and 593. [exhaust flow simulation (wind tunnel tests) of scale model Space Shuttle Orbiter

    Science.gov (United States)

    Baker, L. R.; Sulyma, P. R.; Tevepaugh, J. A.; Penny, M. M.

    1976-01-01

    Since exhaust plumes affect vehicle base environment (pressure and heat loads) and the orbiter vehicle aerodynamic control surface effectiveness, an intensive program involving detailed analytical and experimental investigations of the exhaust plume/vehicle interaction was undertaken as a pertinent part of the overall space shuttle development program. The program, called the Plume Technology program, has as its objective the determination of the criteria for simulating rocket engine (in particular, space shuttle propulsion system) plume-induced aerodynamic effects in a wind tunnel environment. The comprehensive experimental program was conducted using test facilities at NASA's Marshall Space Flight Center and Ames Research Center. A post-test examination of some of the experimental results obtained from NASA-MSFC's 14 x 14-inch trisonic wind tunnel is presented. A description is given of the test facility, simulant gas supply system, nozzle hardware, test procedure and test matrix. Analysis of exhaust plume flow fields and comparison of analytical and experimental exhaust plume data are presented.

  7. Computational fluid dynamics assessment: Volume 1, Computer simulations of the METC (Morgantown Energy Technology Center) entrained-flow gasifier: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Celik, I.; Chattree, M.

    1988-07-01

    An assessment of the theoretical and numerical aspects of the computer code, PCGC-2, is made; and the results of the application of this code to the Morgantown Energy Technology Center (METC) advanced gasification facility entrained-flow reactor, ''the gasifier,'' are presented. PCGC-2 is a code suitable for simulating pulverized coal combustion or gasification under axisymmetric (two-dimensional) flow conditions. The governing equations for the gas and particulate phase have been reviewed. The numerical procedure and the related programming difficulties have been elucidated. A single-particle model similar to the one used in PCGC-2 has been developed, programmed, and applied to some simple situations in order to gain insight to the physics of coal particle heat-up, devolatilization, and char oxidation processes. PCGC-2 was applied to the METC entrained-flow gasifier to study numerically the flash pyrolysis of coal, and gasification of coal with steam or carbon dioxide. The results from the simulations are compared with measurements. The gas and particle residence times, particle temperature, and mass component history were also calculated and the results were analyzed. The results provide useful information for understanding the fundamentals of coal gasification and for assessment of experimental results performed using the reactor considered. 69 refs., 35 figs., 23 tabs.

  8. Embryologically based radical hysterectomy as peritoneal mesometrial resection (PMMR) with pelvic and para-aortic lymphadenectomy for loco-regional tumor control in endometrial cancer: first evidence for efficacy.

    Science.gov (United States)

    Kimmig, Rainer; Iannaccone, Antonella; Aktas, Bahriye; Buderath, Paul; Heubner, Martin

    2016-07-01

    To evaluate the feasibility and efficacy of embryologically based compartmental surgery for locoregional tumor control in intermediate and high risk endometrial cancer: peritoneal mesometrial resection with therapeutic pelvic and para-aortic lymphadenectomy by robotically assisted laparoscopy. 75 consecutive surgically treated patients with uterine malignancies have been analyzed. 68 patients with histologically proven endometrial cancer and complete robotically assisted surgery have been included in this study on morbidity and oncological outcome. 56 % of the patients were at intermediate/high risk with either stage IAG3 or IB (n = 22) or stage II-IV (n = 16). Adjuvant EBRT was offered to three patients only (4 %), whereas five received isolated vaginal brachytherapy (7 %). Indocyanine-green (ICG) fluorescence lymphography is demonstrated being useful for additional intraoperative visualization of the compartment borders and lymphatic drainage to the postponed lymph compartments. After a mean follow-up of 32 months, there were only two loco-regional recurrences (2.9 %). Both recurrences were apparently cured by salvage therapy. 9 patients died; 6 (8.8 %) from metastatic disease (5) or unknown cause (1), 3 (4.4 %) from intercurrent disease without evidence of disease. One patient (1.4 %) experienced a peritoneal carcinosis and is alive. There were 8/68 perioperative complications (12 %). No perioperative mortality was observed. Embryologically defined compartmental surgery by robotically assisted laparoscopy seems to be feasible and safe in endometrial cancer. The low loco-regional recurrence rate of 2.9 % in spite of a very low percentage of adjuvant radiotherapy and 56 % of intermediate/high risk tumors should stimulate to initiate a multicentre trial to evaluate the value of compartmental surgery for prevention of locoregional recurrence in endometrial cancer.

  9. Radiation during deep inspiration allows loco-regional treatment of left breast and axillary-, supraclavicular- and internal mammary lymph nodes without compromising target coverage or dose restrictions to organs at risk.

    Science.gov (United States)

    Hjelstuen, Mari H B; Mjaaland, Ingvil; Vikström, Johan; Dybvik, Kjell Ivar

    2012-03-01

    Loco-regional radiotherapy of left-sided breast cancer represents a treatment planning challenge when the internal mammary chain (IMC) lymph nodes are included in the target volume. This treatment planning study evaluates the reduction in cardiopulmonary doses when radiation is given during deep inspiration breath-hold (DIBH). This was achieved without compromising dose coverage to the planning target volume (PTV). Seventeen patients with early breast cancer, referred for adjuvant radiotherapy, were included. For each patient two computed tomography (CT)-scans were acquired; the first during free breathing (FB) and the second during DIBH. The scans were monitored by the Varian RPM respiratory gating system. Audio-visual guidance was used. The treatment planning of the two CT studies was performed focusing on good coverage (V95% > 98%) of the PTV. Doses to the heart, left anterior descending (LAD) coronary artery, lungs and contralateral breast were assessed. With equal PTV coverage, average mean heart dose was reduced from 6.2 Gy to 3.1 Gy in DIBH plans as compared to FB. Average volume receiving 25 Gy or more (V25Gy) was reduced from 6.7% to 1.2%, and the number of patients with V25Gy > 5% was reduced from 8 to 1 utilizing DIBH. The average mean dose to the LAD coronary artery was reduced from 25.0 Gy to 10.9 Gy. The average ipsilateral lung volume receiving 20 Gy or more (V20Gy) was reduced from 44.5% to 32.7% with DIBH. In 11 of the DIBH plans V20Gy was lower than 35%, in accordance with national guidelines, while none of the FB plans fulfilled this recommendation. Respiratory gated radiotherapy during DIBH is a suitable technique for loco-regional breast irradiation even when IMC lymph nodes are included in the PTV. Cardiopulmonary doses are considerably decreased for all dose levels without compromising the dose coverage to PTV.

  10. Management technique selection of agile manufacture applied to loco. & rolling stock enterprise%机车车辆企业实施敏捷制造的管理技术选择

    Institute of Scientific and Technical Information of China (English)

    常文玉

    2001-01-01

    Agile manufacture is one of the objects that modern assembly enterprises are seeking, however, due to late market involvement for loco. & rolling stock enterprises, agile manufacture is relatively underdeveloped in contrast with other industries. The article, on the basis of analysis of manufacturing and operational characteristics for loco. & rolling stock enterprises and other factors effecting on agile manufacture, studies the promotion caused by integration of TOC, MRP Ⅱ, JIT and other management technique in the field of enterprise plan and control against agile production, and focuses on calculation of restricted factor theoretical output load and methods of plan balance in particular.%机车车辆企业进入市场较晚,相对其它行业的装配企业敏捷化生产比较落后. 在分析机车车辆企业生产运行特点及其敏捷制造的影响因素基础上,研究了制约因素理论(TOC),制造资源计划(MRP Ⅱ)和准时生产技术(JIT)等管理技术在机车车辆企业中计划与控制两方面的集成对敏捷化生产的促进作用,并着重阐述了制约因素理论产量负荷的计算和计划平衡方法.

  11. Caracterização de linhagens endogâmicas recombinantes e mapeamento de locos de características quantitativas associados a ciclo e produtividade do feijoeiro-comum

    Directory of Open Access Journals (Sweden)

    Faleiro Fábio Gelape

    2003-01-01

    Full Text Available O objetivo deste trabalho foi caracterizar 154 linhagens endogâmicas recombinantes por meio da avaliação de características quantitativas, morfológicas, moleculares e de resistência a doenças e mapear locos de características quantitativas associados a ciclo e produtividade do feijoeiro-comum. Adotando o valor do limite de detecção (LOD de 4,0 e uma freqüência máxima de recombinação de 0,40, foram mapeados 43 marcadores em nove grupos de ligação cobrindo uma distância de recombinação total de 247,8 cM. A distância entre marcadores adjacentes variou entre 0 e 28 cM, com média de 7,3 cM. Os grupos de ligação variaram em tamanho de 2,3 a 61,2 cM. Os genes de resistência à ferrugem e à antracnose ficaram localizados no mesmo grupo de ligação. Foram mapeados locos associados às oito características quantitativas estudadas, e a explicação da variância fenotípica pelos marcadores variou de 14,03% a 40,14%. Os resultados encontrados lançam bases para o desenvolvimento de mapas específicos saturados e de utilidade em programas de melhoramento do feijoeiro-comum.

  12. System Simulation Modeling and Key Technology Evaluation in 5G%5G环境下系统级仿真建模与关键技术评估

    Institute of Scientific and Technical Information of China (English)

    李凯; 徐景; 杨旸

    2016-01-01

    根据5G关键技术特征给出了5G系统仿真场景,并提出了一种基于5G系统仿真平台的仿真建模及实现方法。运用动态仿真建模、计算资源虚拟化管理、多核并行仿真以及硬件加速仿真技术建设系统仿真平台,对5G候选关键技术进行评估,可以解决由于5G高复杂度及多变的仿真环境带来的部分问题,并能够提高仿真效率,增强5G系统仿真平台的扩展性。%In this paper, 5G system simulation scenarios based on the features of 5G key technology is introduced, and a simulation modeling and realization method of 5G system simulation platform is presented. By using dynamic simulation modeling, computing resources virtualization management, multi-core paral el simulation and hardware accelerated simulation technology in the system simulation platform construction and 5G key technology evaluation, part of problems bringing by 5G high complex and changeable simulation environment can be solved, and the simulation efficiency can be improved, meanwhile, the scalability of 5G system simulation platform can be enhanced.

  13. Marketing technology in macroeconomics.

    Science.gov (United States)

    Tamegawa, Kenichi

    2012-01-01

    In this paper, we incorporate a marketing technology into a dynamic stochastic general equilibrium model by assuming a matching friction for consumption. An improvement in matching can be interpreted as an increase in matching technology, which we call marketing technology because of similar properties. Using a simulation analysis, we confirm that a positive matching technology shock can increase output and consumption.

  14. 数据链组网与数据传输仿真技术%Technology of Data Link Networking and Data Transmission Simulation

    Institute of Scientific and Technical Information of China (English)

    姜思晓; 房红征

    2016-01-01

    The study of the data link system networking and data transmission technology is very important to the build of the independ-ent data link system and the test&evaluation of the data link system.At the same time,it can not only verify the validity of the designed da-ta link system,but also is useful to understand the main functions of the data link and performance parameters,which can lay the foundation for further research and design of measurement and control data link technology.It analyzed the technology of the data link system,data link networking and the data transmission.Then a brief introduction to the difference between the networking and data transmission technology of the data link system is made.Based on this,it proposed a data link networking and data transmission simulation system scheme,and the function of the system working process are analyzed,which provide the test and evaluation support for the construction of data link.Finally, the construction of the data link and test evaluation system and developing trend is prospected.The validation effect of the proposed methods in the data link test simulation and evaluation system is good,thus providing the reference and basis for the design of the data link system.%研究数据链系统中的组网与数据传输技术,对于构建自主的数据链系统以及数据链系统的测试、评估极为关键;同时,进一步验证所设计的数据链系统的有效性、理解数据链的主要功能与性能参数,为进一步研究与设计测控数据链技术奠定基础;对数据链系统及数据链组网与数据传输技术进行了分析,并简要介绍不同数据链系统的组网与数据传输技术的差别,在此基础上提出一种数据链组网与数据传输仿真系统方案,对系统的功能和工作过程进行了分析,为数据链的构建、测试及评估提供支持;最后,对数据链及其测试评估系统构建及发展趋势进

  15. Technology Advancement for Active Remote Sensing of Carbon Dioxide from Space Using the ASCENDS CarbonHawk Experiment Simulator: First Results

    Science.gov (United States)

    Obland, Michael D.; Nehrir, Amin R.; Lin, Bing; Harrison, F. Wallace; Kooi, Susan; Choi, Yonghoon; Plant, James; Yang, Melissa; Antill, Charles; Campbell, Joel; hide

    2015-01-01

    The ASCENDS CarbonHawk Experiment Simulator (ACES) is a newly developed lidar developed at NASA Langley Research Center and funded by NASA's Earth Science Technology Office (ESTO) Instrument Incubator Program (IIP) that seeks to advance technologies critical to measuring atmospheric column carbon dioxide (CO2) mixing ratios in support of the NASA Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission. The technology advancements targeted include: (1) increasing the power-aperture product to approach ASCENDS mission requirements by implementing multi-aperture telescopes and multiple co-aligned laser transmitters; (2) incorporating high-efficiency, high-power Erbium-Doped Fiber Amplifiers (EDFAs); (3) developing and incorporating a high-bandwidth, low-noise HgCdTe detector and transimpedence amplifier (TIA) subsystem capable of long-duration autonomous operation on Global Hawk aircraft, and (4) advancing algorithms for cloud and aerosol discrimination. The ACES instrument architecture is being developed for operation on high-altitude aircraft and will be directly scalable to meet the ASCENDS mission requirements. These technologies are critical towards developing not only spaceborne instruments but also their airborne simulators, with lower platform requirements for size, mass, and power, and with improved instrument performance for the ASCENDS mission. ACES transmits five laser beams: three from commercial EDFAs operating near 1.57 microns, and two from the Exelis oxygen (O2) Raman fiber laser amplifier system operating near 1.26 microns. The three EDFAs are capable of transmitting up to 10 watts average optical output power each and are seeded by compact, low noise, stable, narrow-linewidth laser sources stabilized with respect to a CO2 absorption line using a multi-pass gas absorption cell. The Integrated-Path Differential Absorption (IPDA) lidar approach is used at both wavelengths to independently measure the CO2 and O2 column number

  16. Virtual Simulation Technology of Semi Submersible Drilling Platform Based on VRML%基于VRML的半潜式海洋平台虚拟仿真技术

    Institute of Scientific and Technical Information of China (English)

    齐明侠; 黄鲁蒙; 许亮斌

    2011-01-01

    There are enormous investment and less domestic offshore platforms in offshore oil development. Staff is not more familiar in deep water drilling technology. In order to overcome the difficulty of staff training, VRML-based semi submersible drilling platform of the virtual tour scene is presented. SolidWorks software of modeling capabilities combined with VRML software of virtual reality modeling language. The technology point of view,sound modeling,VRML nodes of their animation scripting languages such as JavaScript is integrated to use. The main operation of drilling process is simulated,and vivid scene virtual tour to learn having realized.%针对海洋石油开发投资极大,国内海洋平台较少,工作人员对深水钻井工艺较陌生,人员培训费时费力等问题,提出了构建基于VRML的半潜式海洋平台虚拟漫游场景.结合三维软件Solid-Works建模能力与虚拟现实语言VRML强大的仿真能力,综合运用视点技术、声音建模技术、VRML自身的动画节点和JavaScript脚本语言等,实现了海洋钻井主要操作过程的仿真,构建一个生动直观、丰富多彩的虚拟漫游学习场景.

  17. A novel stress-accurate FE technology for highly non-linear analysis with incompressibility constraint. Application to the numerical simulation of the FSW process

    Science.gov (United States)

    Chiumenti, M.; Cervera, M.; Agelet de Saracibar, C.; Dialami, N.

    2013-05-01

    In this work a novel finite element technology based on a three-field mixed formulation is presented. The Variational Multi Scale (VMS) method is used to circumvent the LBB stability condition allowing the use of linear piece-wise interpolations for displacement, stress and pressure fields, respectively. The result is an enhanced stress field approximation which enables for stress-accurate results in nonlinear computational mechanics. The use of an independent nodal variable for the pressure field allows for an adhoc treatment of the incompressibility constraint. This is a mandatory requirement due to the isochoric nature of the plastic strain in metal forming processes. The highly non-linear stress field typically encountered in the Friction Stir Welding (FSW) process is used as an example to show the performance of this new FE technology. The numerical simulation of the FSW process is tackled by means of an Arbitrary-Lagrangian-Eulerian (ALE) formulation. The computational domain is split into three different zones: the work.piece (defined by a rigid visco-plastic behaviour in the Eulerian framework), the pin (within the Lagrangian framework) and finally the stirzone (ALE formulation). A fully coupled thermo-mechanical analysis is introduced showing the heat fluxes generated by the plastic dissipation in the stir-zone (Sheppard rigid-viscoplastic constitutive model) as well as the frictional dissipation at the contact interface (Norton frictional contact model). Finally, tracers have been implemented to show the material flow around the pin allowing a better understanding of the welding mechanism. Numerical results are compared with experimental evidence.

  18. 基于Unity3D的房间仿真技术%Room simulation technology based on Unity3D

    Institute of Scientific and Technical Information of China (English)

    韩桂明; 周凌; 赵志鹏

    2014-01-01

    随着虚拟现实技术的不断发展,3D软件平台在虚拟现实领域起到了关键的作用。本文主要讨论基于Unity3D平台针对虚拟校园的房间仿真关键技术研究及其实现。其内容主要可分为房间3D建模设计和对房间的基本操作设计两个部分。房间的3D建模利用的是3DMax建模软件实现的,其中包括对房间墙壁、窗户、门及内部设备等模型的创建。对房间的基本操作主要是利用Unity3D平台,实现了碰撞区域触发和射线触发碰撞两种开门方法。%With the development of virtual reality technology,the 3D software platform has played a key role in the virtual reality.This paper mainly discusses the key technology and its realization of room simulation in virtual campuses based on Unity 3D.It includes the 3D modeling and basic operation design of the room.The 3D modeling of the room is realized by 3DMax modeling software,including the modeling of the walls,windows,doors and indoor facilities of the room.The basis operation of the room is performed on the Unity3D platform,which helps to realize the two door-opening methods:collision zone trigger and ray trigger collision.

  19. 数控车削仿真中工件加工精度预测技术%Prediction technology of workpiece processing in NC turning simulation

    Institute of Scientific and Technical Information of China (English)

    王占礼

    2012-01-01

    Taking CAK 5085dj CNC machine as an object, we build a model, which includes some indexes such as tool (movement) error, process system stress deformation, thermal deformation and tool wear, to predict the machining accuracy. With artificial neural technology to simulate the relationship between the input and output, it is verified' that the fast and accurate prediction for cutting force can be achieved. By using ABAQUS software, we simulate the cutting temperature field. The experiments for the accuracy of the model are carried and the different between the predicted and the measured is tolerable.%以CAK5085dj型数控车床为研究对象,建立了包括机床几何(运动)误差、工艺系统受力变形、工艺系统受热变形、刀具磨损等多种因素影响的工件加工精度预测综合模型;利用人工神经网络模拟现实复杂系统的输入输出关系,实现对切削力的快速精确预测,并进行试验验证;利用有限元分析软件ABAQUS对切削过程的切削温度场进行了仿真预测及实验验证;进行了工件加工精度预测模型的实验考证,理论预测值与实测值的变化趋势一致,数据基本吻合。

  20. Increasing self-consumption of photovoltaic electricity by storing energy in electric vehicle using smart grid technology in the residential sector. A model for simulating different smart grid programs

    NARCIS (Netherlands)

    Kam, M. van der; Sark, W.G.J.H.M. van

    2014-01-01

    In this paper a model has been developed which intends to simulate the increase of self-consumption of photovoltaic (PV)-power by storing energy in electric vehicle (EV) using smart grid technology in the residential sector. Three different possible smart grid control algorithms for a micro-grid con

  1. Simulating Gravity

    Science.gov (United States)

    Pipinos, Savas

    2010-01-01

    This article describes one classroom activity in which the author simulates the Newtonian gravity, and employs the Euclidean Geometry with the use of new technologies (NT). The prerequisites for this activity were some knowledge of the formulae for a particle free fall in Physics and most certainly, a good understanding of the notion of similarity…

  2. Simulating Gravity

    Science.gov (United States)

    Pipinos, Savas

    2010-01-01

    This article describes one classroom activity in which the author simulates the Newtonian gravity, and employs the Euclidean Geometry with the use of new technologies (NT). The prerequisites for this activity were some knowledge of the formulae for a particle free fall in Physics and most certainly, a good understanding of the notion of similarity…

  3. Segregações gaméticas de locos isoenzímicos em porta-enxertos de citros e suas contribuições alélicas na formação de híbridos

    Directory of Open Access Journals (Sweden)

    Medina Filho Herculano Penna

    2003-01-01

    Full Text Available Estudaram-se os porta-enxertos de citros, Citrus limonia (limão Cravo, C. sunki, (tangerina Sunki, C. aurantium (laranja Azeda e Poncirus trifoliata (Trifoliata por meio de eletroforese horizontal descontínua em gel de amido quanto aos seus genótipos e suas segregações dos locos isoenzímicos Pgi-1, Pgm-1, Got-1, Got-2, Prxa-1, Aps-1 e Me-1, bem como às suas contribuições alélicas a mais de 400 híbridos entre eles. Os locos Me-1 e Aps-1, embora úteis para identificação de híbridos, são homozigotos nos genitores, portanto, inadequados às análises de segregações gaméticas nos genitores e das contribuições alélicas a seus híbridos e foram, por esta razão, desconsiderados. Em Trifoliata, o loco duplicado Got-2, anteriormente descrito com genótipo MT.SS, é na verdade SS.MT, em que S é um alelo de F em Sunki (FF.MM e de F e M em Azeda (FM.MM, enquanto os alelos M e T da duplicação são alelos de M do loco homozigoto MM de Azeda e Sunki, assim determinados pelo padrão de bandas dos híbridos e pela formação dos correspondentes heterodímeros intraloco. Considerando-se 27 segregações para os cinco locos estudados verificou-se a ocorrência de distorções estatisticamente significativas em seis (22% delas. Assumindo-se a ausência de seleção, haja vista as condições ideais de germinação em placas de Petri, a separação dos embriões e a determinação dos genótipos já no primeiro ou segundo par de folhas, os resultados refletem, provavelmente, distorção na proporção dos alelos nos gametas dos genitores, ou transmissão diferencial dos alelos, ou ainda, distinta viabilidade de seus portadores nos zigotos híbridos. Devido à co-dominância dos alelos de isoenzimas, foi possível deduzir a contribuição relativa de cada alelo dos locos heterozigotos dos genitores a partir dos genótipos das progênies híbridas. Não se observaram distorções genotípicas oriundas do genitor Trifoliata, porém ocorreram em

  4. Validated physical models and parameters of bulk 3C–SiC aiming for credible technology computer aided design (TCAD) simulation

    Science.gov (United States)

    Arvanitopoulos, A.; Lophitis, N.; Gyftakis, K. N.; Perkins, S.; Antoniou, M.

    2017-10-01

    The cubic form of SiC (β- or 3C-) compared to the hexagonal α-SiC polytypes, primarily 4H- and 6H–SiC, has lower growth cost and can be grown heteroepitaxially in large area silicon (Si) wafers which makes it of special interest. This in conjunction with the recently reported growth of improved quality 3C–SiC, make the development of devices an imminent objective. However, the readiness of models that accurately predict the material characteristics, properties and performance is an imperative requirement for attaining the design and optimization of functional devices. The purpose of this study is to provide and validate a comprehensive set of models alongside with their parameters for bulk 3C–SiC. The validation process revealed that the proposed models are in a very good agreement to experimental data and confidence ranges were identified. This is the first piece of work achieving that for 3C–SiC. Considerably, it constitutes the necessary step for finite element method simulations and technology computer aided design.

  5. Design and simulation of Low Power Successive Approximation Register for A/D Converters using 0.18um CMOS Technology

    Directory of Open Access Journals (Sweden)

    Kalmeshwar N. Hosur

    2016-04-01

    Full Text Available This Paper presents the design and simulation of low power successive approximation register for the Analog to Digital Converters (ADC using 0.18um CMOS Technology. This acts as digital part of successive approximation ADC. The principle of the Successive Approximation Register (SAR circuit is to determine the value of each bit of the ADC in a sequential manner, depending on the value of the comparator output. If an N bit analog to digital converter is implemented, there are 2N possible conversion output values, which means that the SAR needs at least 2N states and so, as minimum, N FFs. For N bit SAR ADC, the sequence/code register SAR structure requires 2N Flip-Flops and hence power consumption and area occupied is more and Non redundant SAR structure requires N Flip-Flops and a little combinational Logic and hence power consumption is less and area occupied is also less compared to that of Conventional. For 10 bit SAR architecture, the dynamic power consumed by sequence/code register SAR structure is 63.4359uW and non reduandant SAR architecture is 49.2569 uW. The total power reduction using non redundant architecture is 22.35%.

  6. 火星探测器热环境模拟与试验技术探讨%The thermal environment simulation and test technology for Mars probe

    Institute of Scientific and Technical Information of China (English)

    张磊; 刘波涛; 许杰

    2014-01-01

    为保证火星探测器的可靠运行,需要对其进行真空热试验和火星表面热环境模拟试验。文章通过对国外火星探测器热试验的调研,梳理出热试验所涉及的关键技术。并通过对行星际空间热环境和火星表面热环境特点的分析,结合国外相关热环境模拟设备的研制使用情况,探讨不同热环境的地面模拟方法,可为我国火星探测器热环境试验设备的研制及开展相关热试验提供技术参考。%For a Mars probe, the thermal tests in vacuum and Mars surface environment are required. This paper reviews the thermal tests for Mars probes in various countries and the key technologies which would provide a reference for the probe development in our country. The thermal environment characteristics of deep space and Mars surface are analyzed, and the simulation methods of different thermal environments are discussed. A technical guidance is provided for the manufacture of the ground thermal environment test equipment for Mars probe.

  7. The Integration of Group Technology and Simulation Optimization to Solve the Flow Shop with Highly Variable Cycle Time Process: A Surgery Scheduling Case Study

    Directory of Open Access Journals (Sweden)

    T. K. Wang

    2014-01-01

    Full Text Available Surgery scheduling must balance capacity utilization and demand so that the arrival rate does not exceed the effective production rate. However, authorized overtime increases because of random patient arrivals and cycle times. This paper proposes an algorithm that allows the estimation of the mean effective process time and the coefficient of variation. The algorithm quantifies patient flow variability. When the parameters are identified, takt time approach gives a solution that minimizes the variability in production rates and workload, as mentioned in the literature. However, this approach has limitations for the problem of a flow shop with an unbalanced, highly variable cycle time process. The main contribution of the paper is to develop a method called takt time, which is based on group technology. A simulation model is combined with the case study, and the capacity buffers are optimized against the remaining variability for each group. The proposed methodology results in a decrease in the waiting time for each operating room from 46 minutes to 5 minutes and a decrease in overtime from 139 minutes to 75 minutes, which represents an improvement of 89% and 46%, respectively.

  8. 3D Shopping System Based on Scene Simulation Technology%基于视景仿真的3D购物系统

    Institute of Scientific and Technical Information of China (English)

    朱峰

    2014-01-01

    目前大多数的购物网站均呈现千篇一律的方式,无法像现实超市那样给消费者提供一种购物环境,实现文化、心理上的满足和享受。为了弥补以上缺陷,我们考虑将目前最先进的视景仿真技术和信息管理技术融合在一起,基于OSG技术构建3D商业环境及视景漫游、完成基于3D图形界面的购物操作流程。%Most shopping sites, represented as a routine of sameness, are dull in shopping environment, shopping in supermarket, we can be responsed to social, cultural and environmental factors. In order to make up these deficiencies, Visual Environment Simulation and information management tools have been presented in this work. We build a 3D business enviroment and vision roaming based on OSG technology to realize the 3D graphic based shopping process.

  9. Indian emissions of technology-linked NMVOCs with chemical speciation: An evaluation of the SAPRC99 mechanism with WRF-CAMx simulations

    Science.gov (United States)

    Sarkar, M.; Venkataraman, C.; Guttikunda, S.; Sadavarte, P.

    2016-06-01

    Non-methane volatile organic compounds (NMVOCs) are important precursors to reactions producing tropospheric ozone and secondary organic aerosols. The present work uses a detailed technology-linked NMVOC emission database for India, along with a standard mapping method to measured NMVOC profiles, to develop speciated NMVOC emissions, which are aggregated into multiple chemical mechanisms used in chemical transport models. The fully speciated NMVOC emissions inventory with 423 constituent species, was regrouped into model-ready reactivity classes of the RADM2, SAPRC99 and CB-IV chemical mechanisms, and spatially distributed at 25 × 25 km2 resolution, using source-specific spatial proxies. Emissions were considered from four major sectors, i.e. industry, transport, agriculture and residential and from non-combustion activities (use of solvents and paints). It was found that residential cooking with biomass fuels, followed by agricultural residue burning in fields and on-road transport, were largest contributors to the highest reactivity group of NMVOC emissions from India. The emissions were evaluated using WRF-CAMx simulations, using the SAPRC99 photochemical mechanism, over India for contrasting months of April, July and October 2010. Modelled columnar abundance of NO2, CO and O3 agreed well with satellite observations both in magnitude and spatial distribution, in the three contrasting months. Evaluation of monthly and spatial differences between model predictions and observations indicates the need for further refinement of the spatial distribution of NOX emissions, spatio-temporal distribution of agricultural residue burning emissions.

  10. Simulation study of scaled In0.53Ga0.47As and Si FinFETs for sub-16 nm technology nodes

    Science.gov (United States)

    Seoane, N.; Aldegunde, M.; Nagy, D.; Elmessary, M. A.; Indalecio, G.; García-Loureiro, A. J.; Kalna, K.

    2016-07-01

    We investigate the performance and scalability of III-V-OI In0.53Ga0.47As and SOI Si FinFETs using state-of-the-art in-house-built 3D simulation tools. Three different technology nodes specified in the ITRS have been analysed with gate lengths (L G) of 14.0 nm, 12.8 and 10.4 nm for the InGaAs FinFETs and 12.8 nm, 10.7 and 8.1 nm for the Si devices. At a high drain bias, the 12.8 and 10.4 nm InGaAs FinFETs deliver 15% and 13% larger on-currents but 14% larger off-currents than the equivalent 12.8 and 10.7 nm Si FinFETs, respectively. For equivalent gate lengths, both the InGaAs and the Si FinFETs have the same I ON/I OFF ratio (5.9 × 104 when L G = 12.8 nm and 5.7 × 104 when L G = 10.4(10.7) nm). A more pronounced S/D tunnelling affecting the InGaAs FinFETs leads to a larger deterioration in their SS (less than 10%) and DIBL (around 20%) compared to the Si counterparts.

  11. Advances in Tube Hydroforming - An Enabling Technology for Low-Mass Vehicle Manufacturing - Material, Lubrication,Loading, Simulation Issues, and Alternatives

    Institute of Scientific and Technical Information of China (English)

    Muammer Ko(c)

    2004-01-01

    The tube hydroforming process (THF) has recently found a wide application opportunity in the automotive industry, and is of increasing interest to other industries as well. The increased interest stems from the fact that, through the THF process, manufacturers are able to produce complex, consolidated, lightweight parts with reduced number of post-processing than through alternative metal forming techniques. In order to fully realize the benefits of this technology, various aspects have been under investigation in academia and industry world-wide. In this paper, effect of loading path, incoming material variation, and lubrication on the robustness of the hydroforming process and final part specifications are summarized based on previous experimental and computational work. In addition, the simulation of hydroforming and examples are presented in comparison with experimental findings. Briefly, results emphasized the importance of the loading path design whereas material variation within the experimentally tested range was not found to be significantly effective on the final part specifications. Selection of a lubricant for hydroforming of a frame rail part was presented demonstrating several aspects of lubrication selection methodology. Results of friction experiments show that only thickness, axial feeding, and force measurements are good indications of lubricant performance as these are found to be strongly discriminative.

  12. Simulation in International Relations Education.

    Science.gov (United States)

    Starkey, Brigid A.; Blake, Elizabeth L.

    2001-01-01

    Discusses the educational implications of simulations in international relations. Highlights include the development of international relations simulations; the role of technology; the International Communication and Negotiation Simulations (ICONS) project at the University of Maryland; evolving information technology; and simulating real-world…

  13. 食管癌放疗后复发再程调强放疗的临床观察%Clinical efficacy of intensity modulated radiation therapy for loco-regionally recurrent e-sophageal cancer after initial radiotherapy

    Institute of Scientific and Technical Information of China (English)

    彭雷; 卢鑫; 朱兆峰

    2014-01-01

    目的:探讨调强放疗(intensity modulater radiation therapy,IMRT)在食管癌首程放疗后局部复发患者中的应用及临床观察。方法:37例首程放疗后局部复发的食管鳞癌患者,采用调强放疗技术进行二程放疗,处方剂量为(50-60)Gy/[2Gy·(25-30)f]。结果:37例患者中完全缓解(complete response,CR)7例,部分缓解(partial response,PR)20例,有效率(response rate,RR)为73.0%(27/37)。本组患者1、2、3年生存率分别为59.5%、32.4%、21.1%。放射性食管炎、骨髓抑制、胃肠道反应的发生率较高。全部病例随访资料完整。截止2012年12月,25例患者已经死亡,其中死于局部复发11例、远处转移8例、食管气管瘘2例、大出血2例、其他疾病1例、自杀1例。结论:调强放疗对于食管癌首程放疗后局部复发患者是一种较好的有效的治疗方法,能取得较好的局部控制率。%Objective:To evaluate the applications and clinical effect of intensity modulated radiation therapy (IMRT)for loco-regionally recurrent esophageal cancer after initial radiotherapy.Methods:All 37 patients with loco-regionally recurrent esophageal cancer after initial radiotherapy were treated with IMRT,with a total dose of (50-60)Gy/[2Gy·(25 -30)f].Results:Of 37 patients,7 patients achieved completed remission,20 patients achieved partial remission,the effective rate was 73.0%(27/37).The overall 1 -,2 -,3 -year survival rates were 59.5%, 32.4%,21.1%.In the radiation therapy,the incidence rates of radiation esophagitis and arrest of bone marrow were high.In followed up,until December 2012,25 patients died,1 1 from local recurrence,8 from distant metastases,2 from esophageal leak,2 from haemorrhage,1 from other disease,1 from suicide.Conclusion:To patients with loco-regionally recurrent esophageal cancer after initial radiotherapy,IMRT is an alternative effective method,can improve the local

  14. Application of 3D simulation technology in Ophthalmology & Optometry teaching%三维仿真技术在眼视光教学中应用的研究进展

    Institute of Scientific and Technical Information of China (English)

    田甜; 郭长锋

    2013-01-01

    三维仿真技术是指利用计算机技术生成的一个逼真的,具有视、听、触、味等多种感知的虚拟环境,用户可以同虚拟环境中的实体相互作用的一种多媒体技术,其以生动形象的虚拟现实(VR)技术在医学教育方面受到越来越多的重视,也为眼视光学的教育和教学提供了新的发展平台.笔者主要介绍三维仿真模型、三维动画技术、虚拟现实技术在眼视光学和眼科学教学中的具体应用和发展现状.%The three-dimensional simulation technology refers to the technology which can use the computer technology to generate a realistic virtual environment with visual,hearing,touch,taste,and other perception.Users can have interaction with entity in the virtual environment.With its very vivid virtual reality (VR) technology,3D simulation technology has gained more and more attention and provided a new development platform for ophthalmology and optometry teaching.This paper mainly introduced teaching the present development situation and the specific application of the 3D simulation model,3D animation technology,virtual reality technology in optometry and ophthalmology.

  15. Simulation Analysis of Evolution of Supply Chain of Information Technology Based on System Dynamic%基于系统动力学的信息技术供应链的演化仿真分析

    Institute of Scientific and Technical Information of China (English)

    李艳

    2012-01-01

    基于系统动力学的建模和仿真方法,对信息经济社会中信息技术转移的供应链进行分析.回顾文献中关于信息技术引进和吸收的概念、重要性和影响因素的阐述,给出信息技术供应链的概念,并分析信息技术供应链中的因果关系;建立信息技术供应链的因果关系图和流图的系统动力学模型,并在模型的基础上对信息技术供应链进行仿真分析:给出结论和关于信息技术引进、吸收的建议.%The supply chain of information technology is debated based on the simulation of system dynamic in the information economy society. Firstly the concept, importance and impaction factor on the introduction and absorption of information technology are reviewed in the literature. Then the concept of supply chain of information technology is proposed. And the cause - result relation in the supply chain of information technology is given. Then cause - result relation diagram and fluid diagram of system dynamic of supply chain of information technology is created. The simulation of supply chain of information technology based on this model is operated. The conclusion and suggestion on supply chain of information technology is given based on the simulation result.

  16. Combine Harvester Simulator

    DEFF Research Database (Denmark)

    Vilmann, Ole; Sørlie, James Arnold

    1999-01-01

    A simulator for training pilots in the operation of a modern high-tech combine harvester is presented. The new simulator application is based on DMI´s well-known DMS maritime simulator architecture. Two major challenges have been encountered in the development of the simulator: 1) interfacing...... the simulator software and the harvester hardware, and 2) the visual image generation system. Aims of the project have been to promote technology transfer from DMI´s maritime simulator to new application areas, to develop a state-of-the-art pilot training environment, and to utilise the state......-of-the-art in objec-oriented graphics programming technologies....

  17. Radiation during deep inspiration allows loco-regional treatment of left breast and axillary-, supraclavicular- and internal mammary lymph nodes without compromising target coverage or dose restrictions to organs at risk

    Energy Technology Data Exchange (ETDEWEB)

    Hjelstuen, Mari H. B.; Mjaaland, Ingvil; Vikstroem, Johan; Dybvik, Kjell Ivar (Department of Hematology and Oncology, Stavanger University Hospital, Stavanger (Norway)), E-mail: hjem@sus.no

    2012-03-15

    Background and purpose. Loco-regional radiotherapy of left-sided breast cancer represents a treatment planning challenge when the internal mammary chain (IMC) lymph nodes are included in the target volume. This treatment planning study evaluates the reduction in cardiopulmonary doses when radiation is given during deep inspiration breath-hold (DIBH). This was achieved without compromising dose coverage to the planning target volume (PTV). Patients and methods. Seventeen patients with early breast cancer, referred for adjuvant radiotherapy, were included. For each patient two computed tomography (CT)-scans were acquired; the first during free breathing (FB) and the second during DIBH. The scans were monitored by the Varian RPMTM respiratory gating system. Audio-visual guidance was used. The treatment planning of the two CT studies was performed focusing on good coverage (V95% > 98%) of the PTV. Doses to the heart, left anterior descending (LAD) coronary artery, lungs and contralateral breast were assessed. Results. With equal PTV coverage, average mean heart dose was reduced from 6.2 Gy to 3.1 Gy in DIBH plans as compared to FB. Average volume receiving 25 Gy or more (V25Gy) was reduced from 6.7% to 1.2%, and the number of patients with V25Gy > 5% was reduced from 8 to 1 utilizing DIBH. The average mean dose to the LAD coronary artery was reduced from 25.0 Gy to 10.9 Gy. The average ipsilateral lung volume receiving 20 Gy or more (V20Gy) was reduced from 44.5% to 32.7% with DIBH. In 11 of the DIBH plans V20Gy was lower than 35%, in accordance with national guidelines, while none of the FB plans fulfilled this recommendation. Conclusion. Respiratory gated radiotherapy during DIBH is a suitable technique for loco-regional breast irradiation even when IMC lymph nodes are included in the PTV. Cardiopulmonary doses are considerably decreased for all dose levels without compromising the dose coverage to PTV

  18. The Development of Legalization of Student Management in American Public Universities and Its Revelation:From the Perspective of In Loco Parentis Extinction%Journal of Higher Education Management

    Institute of Scientific and Technical Information of China (English)

    桂敏

    2016-01-01

    The doctrine of In Loco Parentis was the dominant doctrine in the legal history of the rela-tionship between American universities & colleges and students for a long time.Until 1960s this doc-trine moves to demise gradually.In this paper,the author briefly describes the history of In Loco Pa-rentis,uses typical cases to analyze the process of judicial review intervention of student management in American public universities,and finds that judicial review will not violate the autonomy of univer-sity necessarily,whereas limited judicial review can help student management become more constitu-tional and rational,and thus protect students′rights more effectively.In this paper,the author also generalizes the experience of student management in American public universities and provides advice to complete relative laws in China.%在美国高校与学生的法律关系史上“代理父母地位说”长期处于主导地位,直到20世纪60年代其地位才发生了动摇,并走向衰亡。文章从“代理父母地位说”发展历史入手,选取典型案例,对司法审查介入美国公立大学的学生管理程序进行分析,认为司法审查并不必然破坏大学的自治权,有限的司法监督可以帮助大学的治理程序合理合宪,有效保障学生权利。同时文章通过总结美国公立大学学生管理的有效经验,进而为我国完善相关立法提供一定的借鉴。

  19. The potential of pyrolysis technology in climate change mitigation - influence of process design and - parameters, simulated in SuperPro Designer software

    Energy Technology Data Exchange (ETDEWEB)

    Thomsen, T.; Hauggaard-Nielsen, H.; Bruun, E.W.; Ahrenfeldt, J.

    2011-01-15

    This report investigates whether or not it would be possible to produce carbon-negative energy from pyrolysis of wheat straw in a series of Danish agricultural scenarios. A combination of process simulation in SuperPro Designer software, correlations derived from literature studies and experimental work, and overall balance calculations has been applied in the process. The study deviates from other studies of pyrolysis and biochar production by the inclusion of substitution energy impact on the overall carbon-balance. Substitution energy is integrated to account for the gap between the energy production from the pyrolysis and the full energy potential of the biomass, quantified by complete conversion in either combustion or gasification systems. It was concluded that it is feasible to produce carbon-negative energy under a variation of different settings, but also that the negative carbon-balance is only robust for the slow pyrolysis scenario. The CO{sub 2} benefit of the most carbon-negative slow pyrolysis process is estimated to be around 10 % of the atmospheric carbon stored in the original biomass when natural gas is applied for energy substitution. This process avoids the emission of around 150-200 kg CO{sub 2}/ton wheat straw with substitution energy with a Denmark 2007 average carbon-intensity. This result is weighted against the net emissions of the carbon-'neutral' process of conventional combustion. This emission is in this report estimated to be around 50 - 150 kg CO{sub 2}/ton straw depending on scenario settings. The final results of the study have been compared to another study with convincing results. Results concluded that the primary force of the pyrolysis technology is the recalcitrant char product and not the pyrolysis oil. Based on this, the study suggests that despite the trend in commercial pyrolysis technology that focuses on fast pyrolysis processes with maximized bio-oil production, the twin challenge of climate mitigation and

  20. Study on the Technology of Compound Preservation in Simulated Crab Meat%模拟蟹肉复合保鲜技术研究

    Institute of Scientific and Technical Information of China (English)

    励建荣; 项方守; 朱军莉; 仪淑敏; 李学鹏; 秦乾安

    2012-01-01

    and sensory methods. The results show that the freezing point of simulated crab meat was (-3.4±0.5)t, and there was no change on it after adding the preservative. The appropriate storage temperature of simulated crab meat was(-2 ± 0.5)℃. The TVC (total number of colonies) of each group were lower than 1 log10 CFU/g, and the simulated crab meat keep a good sensory quality on day 56. The TVC of V1 reached to 3.32 log10 CFU/g on day 70, while the other three groups were also lower than 1 log CFU/g. The TVC of group V2, M1 M2 increased significantly after 70 days storage. The shelf life of group V1 was 84 days, the group M1 and M2 98 days, and the group V2 up to 100 days. The results indicated that the compound preservation could inhibit the reproduction of spoilage organisms, slow down the decline of the quality. Thus, the compound preservation technology shows a good application prospect in the preservation of the simulated crab meat. In addition, TVC, hardness, and gumminess showed significant positive correlation with storage time, while sensory score, cohesiveness and resilience showed significant negative correlation with storage time. Thus those factors could be considered as the quality indicators of simulated crab meat. No significant differences were found in pH, TVB-N, and brightness during the storage, so they were not fit f