Trust Index Based Fault Tolerant Multiple Event Localization Algorithm for WSNs

Directory of Open Access Journals (Sweden)

Jian Wan

2011-06-01

Full Text Available This paper investigates the use of wireless sensor networks for multiple event source localization using binary information from the sensor nodes. The events could continually emit signals whose strength is attenuated inversely proportional to the distance from the source. In this context, faults occur due to various reasons and are manifested when a node reports a wrong decision. In order to reduce the impact of node faults on the accuracy of multiple event localization, we introduce a trust index model to evaluate the fidelity of information which the nodes report and use in the event detection process, and propose the Trust Index based Subtract on Negative Add on Positive (TISNAP localization algorithm, which reduces the impact of faulty nodes on the event localization by decreasing their trust index, to improve the accuracy of event localization and performance of fault tolerance for multiple event source localization. The algorithm includes three phases: first, the sink identifies the cluster nodes to determine the number of events occurred in the entire region by analyzing the binary data reported by all nodes; then, it constructs the likelihood matrix related to the cluster nodes and estimates the location of all events according to the alarmed status and trust index of the nodes around the cluster nodes. Finally, the sink updates the trust index of all nodes according to the fidelity of their information in the previous reporting cycle. The algorithm improves the accuracy of localization and performance of fault tolerance in multiple event source localization. The experiment results show that when the probability of node fault is close to 50%, the algorithm can still accurately determine the number of the events and have better accuracy of localization compared with other algorithms.

Establishing precursor events for stress corrosion cracking initiation in type 304L stainless steel

International Nuclear Information System (INIS)

Khan, M.U.F.; Raja, V.S.; Roychowdhury, S.; Kain, V.

2015-01-01

The present study attempts to establish slip band emergence, due to localized deformation, as a precursor event for SCC initiation in type 304L SS. The unidirectional tensile loading was used for straining flat tensile specimen, less than 10% strain, in air, 0.5 M NaCl + 0.5 M H 2 SO 4 and boiling water reactor (BWR) simulated environment (288 C. degrees, 10 MPa). The surface features were characterized using optical microscopy, scanning electron microscopy (including electron backscattered diffraction-EBSD) and atomic force microscopy. The study shows that with increase in strain level, during unidirectional slow strain rate test (SSRT), average slip band height increases in air and the attack on slip lines occurs in acidified chloride environment. In BWR simulated environment, preferential oxidation on slip lines and initiation of a few cracks on some of the slip lines are observed. Based on the observation, the study suggests slip bands, formed due to localized deformation, to act as a precursor for SCC initiation. (authors)

Analysis of early initiating event(s) in radiation-induced thymic lymphomagenesis

International Nuclear Information System (INIS)

Muto, Masahiro; Ying Chen; Kubo, Eiko; Mita, Kazuei

1996-01-01

Since the T cell receptor rearrangement is a sequential process and unique to the progeny of each clone, we investigated the early initiating events in radiation-induced thymic lymphomagenesis by comparing the oncogenic alterations with the pattern of γ T cell receptor (TCR) rearrangements. We reported previously that after leukemogenic irradiation, preneoplastic cells developed, albeit infrequently, from thymic leukemia antigen-2 + (TL-2 + ) thymocytes. Limited numbers of TL-2 + cells from individual irradiated B10.Thy-1.1 mice were injected into B10.Thy-1.2 mice intrathymically, and the common genetic changes among the donor-type T cell lymphomas were investigated with regard to p53 gene and chromosome aberrations. The results indicated that some mutations in the p53 gene had taken place in these lymphomas, but there was no common mutation among the donor-type lymphomas from individual irradiated mice, suggesting that these mutations were late-occurring events in the process of oncogenesis. On the other hand, there were common chromosome aberrations or translocations such as trisomy 15, t(7F; 10C), t(1A; 13D) or t(6A; XB) among the donor-type lymphomas derived from half of the individual irradiated mice. This indicated that the aberrations/translocations, which occurred in single progenitor cells at the early T cell differentiation either just before or after γ T cell receptor rearrangements, might be important candidates for initiating events. In the donor-type lymphomas from the other half of the individual irradiated mice, microgenetic changes were suggested to be initial events and also might take place in single progenitor cells just before or right after γ TCR rearrangements. (author)

Analysis of the Steam Generator Tubes Rupture Initiating Event

International Nuclear Information System (INIS)

Trillo, A.; Minguez, E.; Munoz, R.; Melendez, E.; Sanchez-Perea, M.; Izquierd, J.M.

1998-01-01

In PSA studies, Event Tree-Fault Tree techniques are used to analyse to consequences associated with the evolution of an initiating event. The Event Tree is built in the sequence identification stage, following the expected behaviour of the plant in a qualitative way. Computer simulation of the sequences is performed mainly to determine the allowed time for operator actions, and do not play a central role in ET validation. The simulation of the sequence evolution can instead be performed by using standard tools, helping the analyst obtain a more realistic ET. Long existing methods and tools can be used to automatism the construction of the event tree associated to a given initiator. These methods automatically construct the ET by simulating the plant behaviour following the initiator, allowing some of the systems to fail during the sequence evolution. Then, the sequences with and without the failure are followed. The outcome of all this is a Dynamic Event Tree. The work described here is the application of one such method to the particular case of the SGTR initiating event. The DYLAM scheduler, designed at the Ispra (Italy) JRC of the European Communities, is used to automatically drive the simulation of all the sequences constituting the Event Tree. Similarly to the static Event Tree, each time a system is demanded, two branches are open: one corresponding to the success and the other to the failure of the system. Both branches are followed by the plant simulator until a new system is demanded, and the process repeats. The plant simulation modelling allows the treatment of degraded sequences that enter into the severe accident domain as well as of success sequences in which long-term cooling is started. (Author)

Selection of initial events of accelerator driven subcritical system

International Nuclear Information System (INIS)

Wang Qianglong; Hu Liqin; Wang Jiaqun; Li Yazhou; Yang Zhiyi

2013-01-01

The Probabilistic Safety Assessment (PSA) is an important tool in reactor safety analysis and a significant reference to the design and operation of reactor. It is the origin and foundation of the PSA for a reactor to select the initial events. Accelerator Driven Subcritical System (ADS) has advanced design characteristics, complicated subsystems and little engineering and operating experience, which makes it much more difficult to identify the initial events of ADS. Based on the current design project of ADS, the system's safety characteristics and special issues were analyzed in this article. After a series of deductions with Master Logic Diagram (MLD) and considering the relating experience of other advanced research reactors, a preliminary initial events was listed finally, which provided the foundation for the next safety assessment. (authors)

Adverse cardiac events in out-patients initiating clozapine treatment

DEFF Research Database (Denmark)

Rohde, C; Polcwiartek, C; Kragholm, K

2018-01-01

OBJECTIVE: Using national Danish registers, we estimated rates of clozapine-associated cardiac adverse events. Rates of undiagnosed myocarditis were estimated by exploring causes of death after clozapine initiation. METHOD: Through nationwide health registers, we identified all out-patients initi......OBJECTIVE: Using national Danish registers, we estimated rates of clozapine-associated cardiac adverse events. Rates of undiagnosed myocarditis were estimated by exploring causes of death after clozapine initiation. METHOD: Through nationwide health registers, we identified all out...... the maximum rate of clozapine-associated fatal myocarditis to 0.28%. CONCLUSION: Cardiac adverse effects in Danish out-patients initiating clozapine treatment are extremely rare and these rates appear to be comparable to those observed for other antipsychotic drugs....

Initiating events in the safety probabilistic analysis of nuclear power plants

International Nuclear Information System (INIS)

Stasiulevicius, R.

1989-01-01

The importance of the initiating event in the probabilistic safety analysis of nuclear power plants are discussed and the basic procedures necessary for preparing reports, quantification and grouping of the events are described. The examples of initiating events with its occurence medium frequency, included those calculated for OCONEE reactor and Angra-1 reactor are presented. (E.G.)

Estimation of initiating event frequency for external flood events by extreme value theorem

International Nuclear Information System (INIS)

Chowdhury, Sourajyoti; Ganguly, Rimpi; Hari, Vibha

2017-01-01

External flood is an important common cause initiating event in nuclear power plants (NPPs). It may potentially lead to severe core damage (SCD) by first causing the failure of the systems required for maintaining the heat sinks and then by contributing to failures of engineered systems designed to mitigate such failures. The sample NPP taken here is twin 220 MWe Indian standard pressurized heavy water reactor (PHWR) situated inland. A comprehensive in-house Level-1 internal event PSA for full power had already been performed. External flood assessment was further conducted in area of external hazard risk assessment in response to post-Fukushima measures taken in nuclear industries. The present paper describes the methodology to calculate initiating event (IE) frequency for external flood events for the sample inland Indian NPP. General extreme value (GEV) theory based on maximum likelihood method (MLM) and order statistics approach (OSA) is used to analyse the rainfall data for the site. Thousand-year return level and necessary return periods for extreme rainfall are evaluated. These results along with plant-specific topographical calculations quantitatively establish that external flooding resulting from upstream dam break, river flooding and heavy rainfall (flash flood) would be unlikely for the sample NPP in consideration.

Controlling spatio-temporal extreme events by decreasing the localized energy

International Nuclear Information System (INIS)

Du Lin; Xu Wei; Li Zhanguo; Zhou Bingchang

2011-01-01

The problem of controlling extreme events in spatially extended dynamical systems is investigated in this Letter. Based on observations of the system state, the control technique we proposed locally decreases the spatial energy of the amplitude in the vicinity of the highest burst, without needs of any knowledge or prediction of the system model. Considering the specific Complex Ginzburg-Landau equation, we provide theoretical analysis for designing the localized state feedback controller. More exactly, a simple control law by varying a damping parameter at control region is chose to achieve the control. Numerical simulations and statistic analysis demonstrate that extreme events can be efficiently suppressed by our strategy. In particular, the cost of the control and the tolerant time delay in applying the control is considered in detail. - Highlights: → We propose a local control scheme to suppress spatio-temporal extreme events. → The control is address by decreasing the spatial energy of the system locally. → The detail control law is to apply localized state feedback based on observations. → The cost of the control increases with the size of the control region exponentially. → The tolerant delay of the control is about 5-6 times of lifetime of extreme events.

Event localization in underwater wireless sensor networks using Monitoring Courses

KAUST Repository

Debont, Matthew John Robert

2012-08-01

We propose m-courses (Monitoring Courses), a novel solution to localize events in an underwater wireless sensor network. These networks consists of surface gateways and relay nodes. GPS can localize the position of surface gateways which can then distribute their locations through the network using acoustic modems. Relay nodes are deployed to remain static, but these untethered nodes may drift due to water currents, resulting in disruption of communication links. We develop a novel underwater alarm system using a cyclic graph model. In the event of link failure, a series of alarm packets are broadcast in the network. These alarms are then captured by the underwater m-courses, which can also be used to assure network connectivity and identify node failures. M-courses also allow the network to localize events and identify network issues locally before forwarding results upwards to a Surface Gateway node. This reduces communication overhead and allows for efficient management of nodes in a mobile network. Our results show that m-course routing reduces the number of sends required to report an event to a Surface Gateway by up to 80% when compared to a naïve routing implementation.

Event Localization in Underwater Wireless Sensor Networks using Monitoring Courses

KAUST Repository

Debont, Matthew

2011-11-01

In this thesis we consider different methods to localize events in a multi-hop wireless sensor network operating underwater using acoustic modems. The network consists of surface gateway nodes and relay nodes. Localization of surface gateways can be achieved through GPS, but we cannot rely on this technology for localizing underwater nodes. Surface Gateway nodes can distribute their locations through the network using the incoming signals by the acoustic modems from the relay nodes. Relay nodes are deployed to remain static but due to water currents, floating, and the untethered nature of the nodes, they often suffer from frequent drifting which can result in a deployed network suffering link failures. In this work, we developed a novel concept of an underwater alarming system, which adapts a cyclic graph model. In the event of link failure, a series of alarm packets are broadcasted in the network. These alarms are then captured through a novel concept of underwater Monitoring Courses (M-Courses), which can also be used to assure network connectivity and identify node faults. M-Courses also allow the network to localize events and identify network issues at a local level before forwarding any results upwards to a Surface Gateway nodes. This reduces the amount of communication overhead needed and allowing for distributed management of nodes in a network which may be constantly moving. We show that the proposed algorithms can reduce the number of send operations needed for an event to be localized in a network. We have found that M-Course routing reduces the number of sends required to report an event to a Surface Gateway by up to 80% in some cases when compared to a naive routing implementation. But this is achieved by increasing the time for an event to reach a Surface Gateway. These effects are both due to the buffering effect of M-Course routing, which allows us to efficiently deal with multiple events in an local area and we find that the performance of M

Initiating events and accidental sequences taken into account in the CAREM reactor design

International Nuclear Information System (INIS)

Kay, J.M.; Felizia, E.R.; Navarro, N.R.; Caruso, G.J.

1990-01-01

The advance made in the nuclear security evaluation of the CAREM reactor is presented. It was carried out using the Security Probabilistic Analysis (SPA). The latter takes into account the different phases of identification and solution of initiating events and the qualitative development of event trees. The method of identification of initiating events is the Master Logical Diagram (MLD), whose deductive basis makes it appropriate for a new design like the one described. The qualitative development of the event trees associated to the identified initiating events, allows identification of those accidental sequences which are to have the security systems in the reactor. (Author) [es

Initiating Events for Multi-Reactor Plant Sites

Energy Technology Data Exchange (ETDEWEB)

Muhlheim, Michael David [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Flanagan, George F. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Poore, III, Willis P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2014-09-01

Inherent in the design of modular reactors is the increased likelihood of events that initiate at a single reactor affecting another reactor. Because of the increased level of interactions between reactors, it is apparent that the Probabilistic Risk Assessments (PRAs) for modular reactor designs need to specifically address the increased interactions and dependencies.

Defining initiating events for purposes of probabilistic safety assessment

International Nuclear Information System (INIS)

1993-09-01

This document is primarily directed towards technical staff involved in the performance or review of plant specific Probabilistic Safety Assessment (PSA). It highlights different approaches and provides typical examples useful for defining the Initiating Events (IE). The document also includes the generic initiating event database, containing about 300 records taken from about 30 plant specific PSAs. In addition to its usefulness during the actual performance of a PSA, the generic IE database is of the utmost importance for peer reviews of PSAs, such as the IAEA's International Peer Review Service (IPERS) where reference to studies on similar NPPs is needed. 60 refs, figs and tabs

The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation.

Science.gov (United States)

Wensveen, Felix M; Valentić, Sonja; Šestan, Marko; Turk Wensveen, Tamara; Polić, Bojan

2015-09-01

Obesity is associated with the accumulation of pro-inflammatory cells in visceral adipose tissue (VAT), which is an important underlying cause of insulin resistance and progression to diabetes mellitus type 2 (DM2). Although the role of pro-inflammatory cytokines in disease development is established, the initiating events leading to immune cell activation remain elusive. Lean adipose tissue is predominantly populated with regulatory cells, such as eosinophils and type 2 innate lymphocytes. These cells maintain tissue homeostasis through the excretion of type 2 cytokines, such as IL-4, IL-5, and IL-13, which keep adipose tissue macrophages (ATMs) in an anti-inflammatory, M2-like state. Diet-induced obesity is associated with the loss of tissue homeostasis and development of type 1 inflammatory responses in VAT, characterized by IFN-γ. A key event is a shift of ATMs toward an M1 phenotype. Recent studies show that obesity-induced adipocyte hypertrophy results in upregulated surface expression of stress markers. Adipose stress is detected by local sentinels, such as NK cells and CD8(+) T cells, which produce IFN-γ, driving M1 ATM polarization. A rapid accumulation of pro-inflammatory cells in VAT follows, leading to inflammation. In this review, we provide an overview of events leading to adipose tissue inflammation, with a special focus on adipose homeostasis and the obesity-induced loss of homeostasis which marks the initiation of VAT inflammation. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The initiating events in the Loviisa nuclear power plant history

International Nuclear Information System (INIS)

Sjoblom, K.

1987-01-01

During the 16 reactor years of Loviisa nuclear power plant operation no serious incident has endangered the high level of safety. The initiating events of plant incidents have been analyzed in order to get a view of plant operational safety experience. The initiating events have been placed in categories similar to those that EPRI uses. However, because of the very small number of scrams the study was extended to also cover transients with a relatively low safety importance in order to get more comprehensive statistics. Human errors, which contributed to 15% of the transients, were a special subject in this study. The conditions under which human failures occurred, and the nature and root causes of the human failures that caused the initiating events were analyzed. For future analyses it was noticed that it would be beneficial to analyze incidents immediately, to consult with the persons directly involved and to develop an international standard format for incident analyses

Methodology for Selecting Initiating Events and Hazards for Consideration in an Extended PSA

International Nuclear Information System (INIS)

Wielenberg, A.; Hage, M.; Loeffler, H.; Alzbutas, R.; Apostol, M.; Bareith, A.; Siklossy, T.; Brac, P.; Burgazzi, L.; Cazzoli, E.; Vitazkova, J.; Cizelj, L.; Prosek, A.; Volkanovski, A.; Hashimoto, K.; Godefroy, F.; Gonzalez, M.; Groudev, P.; Kolar, L.; Kumar, M.; Nitoi, M.; Raimond, E.

2016-01-01

An extended PSA applies to a site of one or several Nuclear Power Plant unit(s) and its environment. It intends to calculate the risk induced by the main sources of radioactivity (reactor core and spent fuel storages) on the site, taking into account all operating states for each main source and all possible relevant accident initiating events (both internal and external) affecting one unit or the whole site. The combination between hazards or initiating events and their impact on a unit or the whole site is a crucial issue for an extended PSA. The report tries to discuss relevant methodologies for this purpose. The report proposes a methodology to select initiating events and hazards for the development of an extended PSA. The proposed methodology for initiating events identification, screening and bounding analysis for an extended PSA consists of four major steps: 1. A comprehensive identification of events and hazards and their respective combinations applicable to the plant and site. Qualitative screening criteria will be applied, 2. The calculation of initial (possibly conservative) frequency claims for events and hazards and their respective combinations applicable to the plant and the site. Quantitative screening criteria will be applied, 3. An impact analysis and bounding assessment for all applicable events and scenarios. Events are either screened out from further more detailed analysis, or are assigned to a bounding event (group), or are retained for detailed analysis, 4. The probabilistic analysis of all retained (bounding) events at the appropriate level of detail. (authors)

Multivariate algorithms for initiating event detection and identification in nuclear power plants

International Nuclear Information System (INIS)

Wu, Shun-Chi; Chen, Kuang-You; Lin, Ting-Han; Chou, Hwai-Pwu

2018-01-01

Highlights: •Multivariate algorithms for NPP initiating event detection and identification. •Recordings from multiple sensors are simultaneously considered for detection. •Both spatial and temporal information is used for event identification. •Untrained event isolation avoids falsely relating an untrained event. •Efficacy of the algorithms is verified with data from the Maanshan NPP simulator. -- Abstract: To prevent escalation of an initiating event into a severe accident, promptly detecting its occurrence and precisely identifying its type are essential. In this study, several multivariate algorithms for initiating event detection and identification are proposed to help maintain safe operations of nuclear power plants (NPPs). By monitoring changes in the NPP sensing variables, an event is detected when the preset thresholds are exceeded. Unlike existing approaches, recordings from sensors of the same type are simultaneously considered for detection, and no subjective reasoning is involved in setting these thresholds. To facilitate efficient event identification, a spatiotemporal feature extractor is proposed. The extracted features consist of the temporal traits used by existing techniques and the spatial signature of an event. Through an F-score-based feature ranking, only those that are most discriminant in classifying the events under consideration will be retained for identification. Moreover, an untrained event isolation scheme is introduced to avoid relating an untrained event to those in the event dataset so that improper recovery actions can be prevented. Results from experiments containing data of 12 event classes and a total of 125 events generated using a Taiwan’s Maanshan NPP simulator are provided to illustrate the efficacy of the proposed algorithms.

Event localization in underwater wireless sensor networks using Monitoring Courses

KAUST Repository

Debont, Matthew John Robert; Jamshaid, Kamran; Shihada, Basem; Ho, Pin-Han

2012-01-01

We propose m-courses (Monitoring Courses), a novel solution to localize events in an underwater wireless sensor network. These networks consists of surface gateways and relay nodes. GPS can localize the position of surface gateways which can

Viability of Event Management Business in Batangas City, Philippine: Basis for Business Operation Initiatives

OpenAIRE

Jeninah Christia D. Borbon

2016-01-01

The research study on Viability of Event Management Business in Batangas City: Basis for Business Operation Initiatives aimed to assess the viability of this type of business using Thompson’s (2005) Dimension of Business Viability as its tool in order to create business operation initiatives. It provided a good framework for defining success factors in entrepreneurial operation initiatives in a specific business type – event management. This study utilized event organizers based i...

On Event Detection and Localization in Acyclic Flow Networks

KAUST Repository

Suresh, Mahima Agumbe

2013-05-01

Acyclic flow networks, present in many infrastructures of national importance (e.g., oil and gas and water distribution systems), have been attracting immense research interest. Existing solutions for detecting and locating attacks against these infrastructures have been proven costly and imprecise, particularly when dealing with large-scale distribution systems. In this article, to the best of our knowledge, for the first time, we investigate how mobile sensor networks can be used for optimal event detection and localization in acyclic flow networks. We propose the idea of using sensors that move along the edges of the network and detect events (i.e., attacks). To localize the events, sensors detect proximity to beacons, which are devices with known placement in the network. We formulate the problem of minimizing the cost of monitoring infrastructure (i.e., minimizing the number of sensors and beacons deployed) in a predetermined zone of interest, while ensuring a degree of coverage by sensors and a required accuracy in locating events using beacons. We propose algorithms for solving the aforementioned problem and demonstrate their effectiveness with results obtained from a realistic flow network simulator.

Development of transient initiating event frequencies for use in probabilistic risk assessments

International Nuclear Information System (INIS)

Mackowiak, D.P.; Gentillon, C.D.; Smith, K.L.

1985-05-01

Transient initiating event frequencies are an essential input to the analysis process of a nuclear power plant probabilistic risk assessment. These frequencies describe events causing or requiring scrams. This report documents an effort to validate and update from other sources a computer-based data file developed by the Electric Power Research Institute (EPRI) describing such events at 52 United States commercial nuclear power plants. Operating information from the United States Nuclear Regulatory Commission on 24 additional plants from their date of commercial operation has been combined with the EPRI data, and the entire data base has been updated to add 1980 through 1983 events for all 76 plants. The validity of the EPRI data and data analysis methodology and the adequacy of the EPRI transient categories are examined. New transient initiating event frequencies are derived from the expanded data base using the EPRI transient categories and data display methods. Upper bounds for these frequencies are also provided. Additional analyses explore changes in the dominant transients, changes in transient outage times and their impact on plant operation, and the effects of power level and scheduled scrams on transient event frequencies. A more rigorous data analysis methodology is developed to encourage further refinement of the transient initiating event frequencies derived herein. Updating the transient event data base resulted in approx.2400 events being added to EPRI's approx.3000-event data file. The resulting frequency estimates were in most cases lower than those reported by EPRI, but no significant order-of-magnitude changes were noted. The average number of transients per year for the combined data base is 8.5 for pressurized water reactors and 7.4 for boiling water reactors

A Study on the Frequency of Initiating Event of OPR-1000 during Outage Periods

Energy Technology Data Exchange (ETDEWEB)

Hong Jae Beol; Jae, Moo Sung [Hanyang Univ., Seoul (Korea, Republic of)

2013-10-15

These sources of data did not reflect the latest event data which have occurred during the PWR outage to the frequencies of initiating event Electric Power Research Institute(EPRI) in USA collected the data of loss of decay heat removal during outage from 1989 to 2009 and published technical report. Domestic operating experiences for LOOP is gathered in Operational Performance Information System for Nuclear Power Plant(OPIS). To reduce conservatism and obtain completeness for LPSD PSA, those data should be collected and used to update the frequencies. The frequencies of LOSDC and LOOP are reevaluated using the data of EPRI and OPIS in this paper. Quantification is conducted to recalculate core damage frequency(CDF), since the rate is changed. The results are discussed below. To make an accurate estimate of the initiating events of LPSD PSA, the event data were collected and the frequencies of initiating events were updated using Bayesian approach. CDF was evaluated through quantification. Δ CDF is -40% and the dominant contributor is pressurizer PSV stuck open event. The most of the event data in EPRI TR were collected from US nuclear power plant industry. Those data are not enough to evaluate outage risk precisely. Therefore, to reduce conservatism and obtain completeness for LPSD PSA, the licensee event report and domestic data should be collected and reflected to the frequencies of the initiating events during outage.

76 FR 15214 - Special Local Regulations for Marine Events; Potomac River, Charles County, MD

Science.gov (United States)

2011-03-21

...-AA08 Special Local Regulations for Marine Events; Potomac River, Charles County, MD AGENCY: Coast Guard... for Marine Events; Potomac River, Charles County, MD'' in the Federal Register (76 FR 1381). We... follows: Sec. 100.35-T05-1113 Special Local Regulations for Marine Events; Potomac River, Charles County...

76 FR 1381 - Special Local Regulations for Marine Events; Potomac River, Charles County, MD

Science.gov (United States)

2011-01-10

...-AA08 Special Local Regulations for Marine Events; Potomac River, Charles County, MD AGENCY: Coast Guard... Regulations for Marine Events; Potomac River, Charles County, MD. (a) Regulated area. The following location... local regulations during the ``Potomac River Sharkfest Swim'' amateur swim, a marine event to be held on...

Understanding Local Energy Initiatives and Preconditions for Business Opportunities

Energy Technology Data Exchange (ETDEWEB)

Jablonska, B. [ECN Policy Studies, Petten (Netherlands); Oostra, M. [TNO, Delft (Netherlands)

2013-09-15

More and more local bottom-up energy initiatives are emerging. Those involved encounter many barriers during the realization of their ideas. As the generation of renewable energy is mostly included, these local initiatives contribute to the targets set at regional, national and EU level. At the same time, they are an indication that end-users themselves want to be part of the energy transition. What are the reasons for citizens to organize themselves and start and initiative? What kind of barriers do they encounter? What does this mean for roles and responsibilities of professionals? And to what kind of opportunities does this lead for products and services? Answers to these questions provide a solid starting point to develop methods and instruments to stimulate, facilitate and upscale local energy initiatives. This paper bundles the outcomes of three workshops and three additional interviews in the Netherlands as part of the European E-hub project. Conclusions can be drawn on needs and drivers, barriers, risks and solutions (lessons learned), possible roles for professionals and opportunities for new products and services.

Development of transient initiating event frequencies for use in probabilistic risk assessments

Energy Technology Data Exchange (ETDEWEB)

Mackowiak, D.P.; Gentillon, C.D.; Smith, K.L.

1985-05-01

Transient initiating event frequencies are an essential input to the analysis process of a nuclear power plant probabilistic risk assessment. These frequencies describe events causing or requiring scrams. This report documents an effort to validate and update from other sources a computer-based data file developed by the Electric Power Research Institute (EPRI) describing such events at 52 United States commercial nuclear power plants. Operating information from the United States Nuclear Regulatory Commission on 24 additional plants from their date of commercial operation has been combined with the EPRI data, and the entire data base has been updated to add 1980 through 1983 events for all 76 plants. The validity of the EPRI data and data analysis methodology and the adequacy of the EPRI transient categories are examined. New transient initiating event frequencies are derived from the expanded data base using the EPRI transient categories and data display methods. Upper bounds for these frequencies are also provided. Additional analyses explore changes in the dominant transients, changes in transient outage times and their impact on plant operation, and the effects of power level and scheduled scrams on transient event frequencies. A more rigorous data analysis methodology is developed to encourage further refinement of the transient initiating event frequencies derived herein. Updating the transient event data base resulted in approx.2400 events being added to EPRI's approx.3000-event data file. The resulting frequency estimates were in most cases lower than those reported by EPRI, but no significant order-of-magnitude changes were noted. The average number of transients per year for the combined data base is 8.5 for pressurized water reactors and 7.4 for boiling water reactors.

Project management initiative local development through specialized training.

Directory of Open Access Journals (Sweden)

Neisy Ramos Acevedo

2013-09-01

Full Text Available The local development should complete a group of basic principles, such as: the design for training and the tools information adapted to the particularity of each territory. This training facilitates, also, the articulation of the stocks deployed by the local leaders, and it increases the administration of the knowledge and the transfer of technologies, processes in those that the nexuses are enlarged between the structures and the population, and where the participation of different present actors is potentialized in the territory. During the year 2010 the Ministry of Economy and Planning begins to offer the possibility to finance projects for the local development, nevertheless these initiatives should be accompanied by a rigorous study of feasibility of the investments. The University of Sancti Spíritus, committed in this zeal, designs the Diplomate of Administration of Projects for Local Initiatives, which offers theoretical tools and it develops practical abilities in the different actors of the local development that facilitate the realization of these studies. The exercise of this graduate's culmination consists on the defence of the study of feasibility of those projects that each municipality identifies as priority for its development.

Developing Public Health Initiatives through Understanding Motivations of the Audience at Mass-Gathering Events.

Science.gov (United States)

Hutton, Alison; Ranse, Jamie; Munn, Matthew Brendan

2018-04-01

This report identifies what is known about audience motivations at three different mass-gathering events: outdoor music festivals, religious events, and sporting events. In light of these motivations, the paper discusses how these can be harnessed by the event organizer and Emergency Medical Services. Lastly, motivations tell what kinds of interventions can be used to achieve an understanding of audience characteristics and the opportunity to develop tailor-made programs to maximize safety and make long-lasting public health interventions to a particular "cohort" or event population. A lot of these will depend on what the risks/hazards are with the particular populations in order to "target" them with public health interventions. Audience motivations tell the event organizer and Emergency Medical Services about the types of behaviors they should expect from the audience and how this may affect their health while at the event. Through these understandings, health promotion and event safety messages can be developed for a particular type of mass-gathering event based on the likely composition of the audience in attendance. Health promotion and providing public information should be at the core of any mass-gathering event to minimize public health risk and to provide opportunities for the promotion of healthy behaviors in the local population. Audience motivations are a key element to identify and agree on what public health information is needed for the event audience. A more developed understanding of audience behavior provides critical information for event planners, event risk managers, and Emergency Medical Services personnel to better predict and plan to minimize risk and reduce patient presentations at events. Mass-gathering event organizers and designers intend their events to be positive experiences and to have meaning for those who attend. Therefore, continual vigilance to improve public health effectiveness and efficiency can become best practice at events

Forecasting of integral parameters of solar cosmic ray events according to initial characteristics of an event

International Nuclear Information System (INIS)

Belovskij, M.N.; Ochelkov, Yu.P.

1981-01-01

The forecasting method for an integral proton flux of solar cosmic rays (SCR) based on the initial characteristics of the phe-- nomenon is proposed. The efficiency of the method is grounded. The accuracy of forecasting is estimated and the retrospective forecasting of real events is carried out. The parameters of the universal function describing the time progress of the SCR events are pre-- sented. The proposed method is suitable for forecasting practically all the SCR events. The timeliness of the given forecasting is not worse than that of the forecasting based on utilization of the SCR propagation models [ru

Local and national initiatives to motivate young people for engineering & ICT

NARCIS (Netherlands)

Ir. Dick van Schenk Brill; Ing Peter van den Berg

2009-01-01

Described are a number of national and local initiatives that are taken to motivate young people to choose for technical education. From the local initiatives we focus on the area where Fontys and Actemium are located; the southeast of the Netherlands. Not only governmental organizations and

Viability of Event Management Business in Batangas City, Philippine: Basis for Business Operation Initiatives

Directory of Open Access Journals (Sweden)

Jeninah Christia D. Borbon

2016-11-01

Full Text Available The research study on Viability of Event Management Business in Batangas City: Basis for Business Operation Initiatives aimed to assess the viability of this type of business using Thompson’s (2005 Dimension of Business Viability as its tool in order to create business operation initiatives. It provided a good framework for defining success factors in entrepreneurial operation initiatives in a specific business type – event management. This study utilized event organizers based in Batangas, a southern popular province, which also is a great popular destination for many types of events. Findings showed that the event management business in Batangas City is generally a personal event type of business whose year of operation ranges from one to three years, mostly link to church or reception venues and usually offers on the day coordination. In the assessment of its perceived viability, it was found out that this type of business is moderately viable in terms of market, technical, business model, management model, economic and financial, and exit strategy. Among all the dimensions tested, only market, management model, economic and financial, and exit strategy showed significant relationship with the profile variables of the event management business. From the enumerated problems encountered, those that got the highest rate were demanding clients, overbooking of reservation/exceeding number of guests and failure to meet spectators and/or competitors expectations. And, the recommended business operation initiatives were based on the weaknesses discovered using Thompson’s Dimension of Business Viability Model.

Cooperative Robot Localization Using Event-Triggered Estimation

Science.gov (United States)

Iglesias Echevarria, David I.

It is known that multiple robot systems that need to cooperate to perform certain activities or tasks incur in high energy costs that hinder their autonomous functioning and limit the benefits provided to humans by these kinds of platforms. This work presents a communications-based method for cooperative robot localization. Implementing concepts from event-triggered estimation, used with success in the field of wireless sensor networks but rarely to do robot localization, agents are able to only send measurements to their neighbors when the expected novelty in this information is high. Since all agents know the condition that triggers a measurement to be sent or not, the lack of a measurement is therefore informative and fused into state estimates. In the case agents do not receive either direct nor indirect measurements of all others, the agents employ a covariance intersection fusion rule in order to keep the local covariance error metric bounded. A comprehensive analysis of the proposed algorithm and its estimation performance in a variety of scenarios is performed, and the algorithm is compared to similar cooperative localization approaches. Extensive simulations are performed that illustrate the effectiveness of this method.

The role local initiatives in community based disaster risk management in Kemijen, Semarang City

Science.gov (United States)

Fauzie, W. Z.; Sariffudin, S.

2017-06-01

Community-based disaster risk reduction is one of the homegrown initiatives efforts and community empowerment oriented in disaster management. This approach is very important because no one can understand the conditions in a region better than the local communities. Therefore, the implementation of CBDRM always emphasize local initiatives in decision making. The existence of local initiative is necessary specially to anticipate the impact of climate change which is increasingly affecting towns in coastal areas, including settlements in Semarang. Kemijen Urban Village is one of the informal settlements in Semarang, which has the highest intensity of flood that is 12 times during 5 years (2011-2015). The research question is how the level of local initiatives in flood disaster management in Kemijen, Semarang? This study aims to assess the level of local initiatives in Kemijen as the community adaptive capacity of flood prevention in pre-disaster, emergency response, and post-disaster. Local initiatives assessed on water supply, sanitation, food, shelter, health, drainage maintenance and waste management. This study shows the level of local initiatives in pre-disaster and post-disaster is almost same and bigger than the response phase. Scoring results showed that pre-disaster is 35.002, 27.9577 for emergency response, and post-disaster is 34.9862 with each category that is independent, empowered, and independent. This study also shows that local initiatives in Kemijen largely formed by individual initiative and only a few were formed by a collective initiative.

77 FR 6708 - Special Local Regulations for Marine Events; Potomac River, Charles County, MD

Science.gov (United States)

2012-02-09

...-AA08 Special Local Regulations for Marine Events; Potomac River, Charles County, MD AGENCY: Coast Guard... River, Charles County, MD. (a) Regulated area. The following location is a regulated area: All waters of... local regulations during the ``Potomac River Sharkfest Swim'' amateur swim, a marine event to be held on...

The Economic and Touristic Regeneration of Local Communities through the Long Tail of Events

Directory of Open Access Journals (Sweden)

Mario Calabrese

2016-11-01

Full Text Available The aim of this study is to demonstrate, in the light of new technologies, the importance of the “long tail” of events for the development of local communities from the economic and tourism standpoint. From the management perspective, an event represents a relevant touristic driver, especially when oriented to small communities. The methodology used, albeit referring to the positive method, incorporates the concept of Chris Anderson’s “long tail” and recent conceptualizations of the Viable Systems Approach. Thus, it refers to literature review method and theory development. Findings of this study emphasize a new perspective of creating value for the development of local communities, based on the evolution of the concept of event (from the mass event to the mass of events. The existing literature on the subject has generally deepened the organizational implications arising from the standardization of events rather than those of customization. Therefore, referring to the originality and value of the present research, it considers the pure customization, which provides even a custom design of the event, a decisive factor for the economic and touristic development of local communities. The study presents also practical implications related with the possibility, thanks to new technologies, to convey to the user/citizen an event that is differentiated and personalized.

Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks

Science.gov (United States)

Amin, Hayder; Maccione, Alessandro; Nieus, Thierry

2017-01-01

Developing neuronal systems intrinsically generate coordinated spontaneous activity that propagates by involving a large number of synchronously firing neurons. In vivo, waves of spikes transiently characterize the activity of developing brain circuits and are fundamental for activity-dependent circuit formation. In vitro, coordinated spontaneous spiking activity, or network bursts (NBs), interleaved within periods of asynchronous spikes emerge during the development of 2D and 3D neuronal cultures. Several studies have investigated this type of activity and its dynamics, but how a neuronal system generates these coordinated events remains unclear. Here, we investigate at a cellular level the generation of network bursts in spontaneously active neuronal cultures by exploiting high-resolution multielectrode array recordings and computational network modelling. Our analysis reveals that NBs are generated in specialized regions of the network (functional neuronal communities) that feature neuronal links with high cross-correlation peak values, sub-millisecond lags and that share very similar structural connectivity motifs providing recurrent interactions. We show that the particular properties of these local structures enable locally amplifying spontaneous asynchronous spikes and that this mechanism can lead to the initiation of NBs. Through the analysis of simulated and experimental data, we also show that AMPA currents drive the coordinated activity, while NMDA and GABA currents are only involved in shaping the dynamics of NBs. Overall, our results suggest that the presence of functional neuronal communities with recurrent local connections allows a neuronal system to generate spontaneous coordinated spiking activity events. As suggested by the rules used for implementing our computational model, such functional communities might naturally emerge during network development by following simple constraints on distance-based connectivity. PMID:28749937

Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks.

Directory of Open Access Journals (Sweden)

Davide Lonardoni

2017-07-01

Full Text Available Developing neuronal systems intrinsically generate coordinated spontaneous activity that propagates by involving a large number of synchronously firing neurons. In vivo, waves of spikes transiently characterize the activity of developing brain circuits and are fundamental for activity-dependent circuit formation. In vitro, coordinated spontaneous spiking activity, or network bursts (NBs, interleaved within periods of asynchronous spikes emerge during the development of 2D and 3D neuronal cultures. Several studies have investigated this type of activity and its dynamics, but how a neuronal system generates these coordinated events remains unclear. Here, we investigate at a cellular level the generation of network bursts in spontaneously active neuronal cultures by exploiting high-resolution multielectrode array recordings and computational network modelling. Our analysis reveals that NBs are generated in specialized regions of the network (functional neuronal communities that feature neuronal links with high cross-correlation peak values, sub-millisecond lags and that share very similar structural connectivity motifs providing recurrent interactions. We show that the particular properties of these local structures enable locally amplifying spontaneous asynchronous spikes and that this mechanism can lead to the initiation of NBs. Through the analysis of simulated and experimental data, we also show that AMPA currents drive the coordinated activity, while NMDA and GABA currents are only involved in shaping the dynamics of NBs. Overall, our results suggest that the presence of functional neuronal communities with recurrent local connections allows a neuronal system to generate spontaneous coordinated spiking activity events. As suggested by the rules used for implementing our computational model, such functional communities might naturally emerge during network development by following simple constraints on distance-based connectivity.

The Urban Leaders Adaptation Initiative: Climate Resilient Local Governments

Science.gov (United States)

Foster, J. G.

2008-12-01

Local governments, the first responders to public health, safety and environmental hazards, must act now to lessen vulnerabilities to climate change. They must plan for and invest in "adapting" to inevitable impacts such as flood, fire, and draught that will occur notwithstanding best efforts to mitigate climate change. CCAP's Urban Leaders Adaptation Initiative is developing a framework for informed decision making on climate adaptation. Looking ahead to projected climate impacts and 'back casting' can identify what is needed now to both reduce greenhouse gas emissions and build local resiliency to climate change. CCAP's partnership with King County (WA), Chicago, Los Angeles, Miami-Dade County (FL), Milwaukee, Nassau County (NY), Phoenix, San Francisco, and Toronto is advancing policy discussions to ensure that state and local governments consider climate change when making decisions about infrastructure, transportation, land use, and resource management. Through the Initiative, local leaders will incorporate climate change into daily urban management and planning activities, proactively engage city and county managers and the public in developing solutions, and build community resilience. One goal is to change both institutional and public attitudes and behaviors. Determining appropriate adaptation strategies for each jurisdiction requires Asking the Climate Question: "How does what we are doing increase our resilience to climate change?" Over the next three years, the Initiative will design and implement specific adaptation plans, policies and 'catalytic' projects, collect and disseminate "best practices," and participate in framing national climate policy discussions. In the coming years, policy-makers will have to consider climate change in major infrastructure development decisions. If they are to be successful and have the resources they need, national climate change policy and emerging legislation will have to support these communities. The Urban Leaders

Single event upset threshold estimation based on local laser irradiation

International Nuclear Information System (INIS)

Chumakov, A.I.; Egorov, A.N.; Mavritsky, O.B.; Yanenko, A.V.

1999-01-01

An approach for estimation of ion-induced SEU threshold based on local laser irradiation is presented. Comparative experiment and software simulation research were performed at various pulse duration and spot size. Correlation of single event threshold LET to upset threshold laser energy under local irradiation was found. The computer analysis of local laser irradiation of IC structures was developed for SEU threshold LET estimation. The correlation of local laser threshold energy with SEU threshold LET was shown. Two estimation techniques were suggested. The first one is based on the determination of local laser threshold dose taking into account the relation of sensitive area to local irradiated area. The second technique uses the photocurrent peak value instead of this relation. The agreement between the predicted and experimental results demonstrates the applicability of this approach. (authors)

Overview of results and perspectives from the Shoreham major common-cause initiating events study

International Nuclear Information System (INIS)

Joksimovich, V.; Orvis, D.D.; Paccione, R.J.

1986-01-01

This study represents the continuation of a large effort by LILCO to fully understand the potential hazards posed by future operation of the Shoreham Nuclear Power Stations (SNPS). The Shoreham Probabilistic Risk Assessment, a level 3 PRA without external events, provided a characterization of the accident sequences that could leave the core in a condition in which it would be vulnerable to severe damage if further mitigating actions were not taken. It estimated the frequency and magnitude of the potential radioactivity releases associated with such sequences. The study was limited to accident sequences initiated by so called internal events to the plant including a loss of offsite power. It also characterized the public risk associated with those accident sequences. The ''Major Common-Cause Initiating Events Study'' (MCCI) for the Shoreham plant was performed to obtain insights into the plant's susceptibility to, and inherent defenses against, certain MCCIs. Major common-cause initiating events are occurrences which have the potential to initiate a plant transient or LOCA and, also, damage one or more plant systems needed to mitigate the effects of a transient or LOCA. The scope of the MCCI study included detailed analyses of seismic events and fires through the severe core damage and bounding analyses of aircraft crashes, windstorms, turbine missiles and release of hazardous materials near the plant

Abnormal Event Detection Using Local Sparse Representation

DEFF Research Database (Denmark)

Ren, Huamin; Moeslund, Thomas B.

2014-01-01

We propose to detect abnormal events via a sparse subspace clustering algorithm. Unlike most existing approaches, which search for optimized normal bases and detect abnormality based on least square error or reconstruction error from the learned normal patterns, we propose an abnormality measurem...... is found that satisfies: the distance between its local space and the normal space is large. We evaluate our method on two public benchmark datasets: UCSD and Subway Entrance datasets. The comparison to the state-of-the-art methods validate our method's effectiveness....

Calculation of noninformative prior of reliability parameter and initiating event frequency with Jeffreys method

International Nuclear Information System (INIS)

He Jie; Zhang Binbin

2013-01-01

In the probabilistic safety assessment (PSA) of nuclear power plants, there are few historical records on some initiating event frequencies or component failures in industry. In order to determine the noninformative priors of such reliability parameters and initiating event frequencies, the Jeffreys method in Bayesian statistics was employed. The mathematical mechanism of the Jeffreys prior and the simplified constrained noninformative distribution (SCNID) were elaborated in this paper. The Jeffreys noninformative formulas and the credible intervals of the Gamma-Poisson and Beta-Binomial models were introduced. As an example, the small break loss-of-coolant accident (SLOCA) was employed to show the application of the Jeffreys prior in determining an initiating event frequency. The result shows that the Jeffreys method is an effective method for noninformative prior calculation. (authors)

Identification and selection of initiating events for experimental fusion facilities

International Nuclear Information System (INIS)

Cadwallader, L.C.

1989-01-01

This paper describes the current approaches used in probabilistic risk assessment (PRA) to identify and select accident initiating events for study in either probabilistic safety analysis or PRA. Current methods directly apply to fusion facilities as well as other types of industries, such as chemical processing and nuclear fission. These identification and selection methods include the Master Logic Diagram, historical document review, system level Failure Modes and Effects Analysis, and others. A combination of the historical document review, such as Safety Analysis Reports and fusion safety studies, and the Master Logic Diagram with appropriate quality assurance reviews, is suggested for standardizing US fusion PRA effects. A preliminary set of generalized initiating events applicable to fusion facilities derived from safety document review is presented as a framework to start from for the historical document review and Master Logic Diagram approach. Fusion designers should find this list useful for their design reviews. 29 refs., 2 tabs

Identification and selection of initiating events for experimental fusion facilities

International Nuclear Information System (INIS)

Cadwallader, L.C.

1989-01-01

This paper describes the current approaches used in probabilistic risk assessment (PRA) to identify and select accident initiating events for study in either probabilistic safety analysis or PRA. Current methods directly apply to fusion facilities as well as other types of industries, such as chemical processing and nuclear fission. These identification and selection methods include the Master Logic Diagram, historical document review, system level Failure Modes and Effects Analysis, and others. A combination of the historical document review, such as Safety Analysis Reports and fusion safety studies, and the Master Logic Diagram with appropriate quality assurance reviews, is suggested for standardizing U.S. fusion PRA efforts. A preliminary set of generalized initiating events applicable to fusion facilities derived from safety document review is presented as a framework to start from for the historical document review and Master Logic Diagram approach. Fusion designers should find this list useful for their design reviews. 29 refs., 1 tab

Containment performance evaluation for the GESSAR-II plant for seismic initiating events

International Nuclear Information System (INIS)

Shiu, K.K.; Chu, T.; Ludewig, H.; Pratt, W.T.

1986-01-01

As a part of the overall effort undertaken by Brookhaven National Laboratory (BNL) to review the GESSAR-II probabilistic risk assessment, an independent containment performance evaluation was performed using the containment event tree approach. This evaluation focused principally on those accident sequences which are initiated by seismic events. This paper reports the findings of this study. 1 ref

Sensitivity of a Simulated Derecho Event to Model Initial Conditions

Science.gov (United States)

Wang, Wei

2014-05-01

Since 2003, the MMM division at NCAR has been experimenting cloud-permitting scale weather forecasting using Weather Research and Forecasting (WRF) model. Over the years, we've tested different model physics, and tried different initial and boundary conditions. Not surprisingly, we found that the model's forecasts are more sensitive to the initial conditions than model physics. In 2012 real-time experiment, WRF-DART (Data Assimilation Research Testbed) at 15 km was employed to produce initial conditions for twice-a-day forecast at 3 km. On June 29, this forecast system captured one of the most destructive derecho event on record. In this presentation, we will examine forecast sensitivity to different model initial conditions, and try to understand the important features that may contribute to the success of the forecast.

Analysis of the initiating events in HIV-1 particle assembly and genome packaging.

Directory of Open Access Journals (Sweden)

Sebla B Kutluay

2010-11-01

Full Text Available HIV-1 Gag drives a number of events during the genesis of virions and is the only viral protein required for the assembly of virus-like particles in vitro and in cells. Although a reasonable understanding of the processes that accompany the later stages of HIV-1 assembly has accrued, events that occur at the initiation of assembly are less well defined. In this regard, important uncertainties include where in the cell Gag first multimerizes and interacts with the viral RNA, and whether Gag-RNA interaction requires or induces Gag multimerization in a living cell. To address these questions, we developed assays in which protein crosslinking and RNA/protein co-immunoprecipitation were coupled with membrane flotation analyses in transfected or infected cells. We found that interaction between Gag and viral RNA occurred in the cytoplasm and was independent of the ability of Gag to localize to the plasma membrane. However, Gag:RNA binding was stabilized by the C-terminal domain (CTD of capsid (CA, which participates in Gag-Gag interactions. We also found that Gag was present as monomers and low-order multimers (e.g. dimers but did not form higher-order multimers in the cytoplasm. Rather, high-order multimers formed only at the plasma membrane and required the presence of a membrane-binding signal, but not a Gag domain (the CA-CTD that is essential for complete particle assembly. Finally, sequential RNA-immunoprecipitation assays indicated that at least a fraction of Gag molecules can form multimers on viral genomes in the cytoplasm. Taken together, our results suggest that HIV-1 particle assembly is initiated by the interaction between Gag and viral RNA in the cytoplasm and that this initial Gag-RNA encounter involves Gag monomers or low order multimers. These interactions per se do not induce or require high-order Gag multimerization in the cytoplasm. Instead, membrane interactions are necessary for higher order Gag multimerization and subsequent

Initial-state parton shower kinematics for NLO event generators

International Nuclear Information System (INIS)

Odaka, Shigeru; Kurihara, Yoshimasa

2007-01-01

We are developing a consistent method to combine tree-level event generators for hadron collision interactions with those including one additional QCD radiation from the initial-state partons, based on the limited leading-log (LLL) subtraction method, aiming at an application to NLO event generators. In this method, a boundary between non-radiative and radiative processes necessarily appears at the factorization scale (μ F ). The radiation effects are simulated using a parton shower (PS) in non-radiative processes. It is therefore crucial in our method to apply a PS which well reproduces the radiation activities evaluated from the matrix-element (ME) calculations for radiative processes. The PS activity depends on the applied kinematics model. In this paper we introduce two models for our simple initial-state leading-log PS: a model similar to the 'old' PYTHIA-PS and a p T -prefixed model motivated by ME calculations. PS simulations employing these models are tested using W-boson production at LHC as an example. Both simulations show a smooth matching to the LLL subtracted W+1 jet simulation in the p T distribution of W bosons, and the summed p T spectra are stable against a variation of μ F , despite that the p T -prefixed PS results in an apparently harder p T spectrum. (orig.)

Abnormal global and local event detection in compressive sensing domain

Science.gov (United States)

Wang, Tian; Qiao, Meina; Chen, Jie; Wang, Chuanyun; Zhang, Wenjia; Snoussi, Hichem

2018-05-01

Abnormal event detection, also known as anomaly detection, is one challenging task in security video surveillance. It is important to develop effective and robust movement representation models for global and local abnormal event detection to fight against factors such as occlusion and illumination change. In this paper, a new algorithm is proposed. It can locate the abnormal events on one frame, and detect the global abnormal frame. The proposed algorithm employs a sparse measurement matrix designed to represent the movement feature based on optical flow efficiently. Then, the abnormal detection mission is constructed as a one-class classification task via merely learning from the training normal samples. Experiments demonstrate that our algorithm performs well on the benchmark abnormal detection datasets against state-of-the-art methods.

A study on the determination of threshold values for the initiating event performance indicators of domestic nuclear power plants

International Nuclear Information System (INIS)

Kang, D. I.; Park, J. H.; Kim, K. Y.; Whang, M. J.; Yang, J. E.; Sung, G. Y.

2003-01-01

In this paper, we determine the threshold values of unplanned reactor scram, domestic initiating event performance indicator, using data of domestic unplanned reactor scram and probabilistic safety assessment model of Korea Standard Nuclear Power Plant(KSNP). We also perform a pilot study of initiating event Risk Based Performance Indicator(RBPI) for KSNP. Study results for unplanned reactor scram show that the threshold value of between green and blue color is 3, that of between blue and yellow color is 6, and that of between yellow and orange color is 30. Pilot study results of initiating event RBPI show that loss of feedwater, transient, and loss of component cooling water events are selected as initiating event RBPI for KSNP

78 FR 68995 - Special Local Regulation; Southern California Annual Marine Events for the San Diego Captain of...

Science.gov (United States)

2013-11-18

... notification of this enforcement period via the Local Notice to Mariners and local advertising by the event... Broadcast Notice to Mariners or other communications coordinated by the event sponsor to grant general...

78 FR 66844 - Special Local Regulation; Southern California Annual Marine Events for the San Diego Captain of...

Science.gov (United States)

2013-11-07

... notification of this enforcement period via the Local Notice to Mariners and local advertising by the event... Broadcast Notice to Mariners or other communications coordinated by the event sponsor to grant general...

Identification of spatially-localized initial conditions via sparse PCA

Science.gov (United States)

Dwivedi, Anubhav; Jovanovic, Mihailo

2017-11-01

Principal Component Analysis involves maximization of a quadratic form subject to a quadratic constraint on the initial flow perturbations and it is routinely used to identify the most energetic flow structures. For general flow configurations, principal components can be efficiently computed via power iteration of the forward and adjoint governing equations. However, the resulting flow structures typically have a large spatial support leading to a question of physical realizability. To obtain spatially-localized structures, we modify the quadratic constraint on the initial condition to include a convex combination with an additional regularization term which promotes sparsity in the physical domain. We formulate this constrained optimization problem as a nonlinear eigenvalue problem and employ an inverse power-iteration-based method to solve it. The resulting solution is guaranteed to converge to a nonlinear eigenvector which becomes increasingly localized as our emphasis on sparsity increases. We use several fluids examples to demonstrate that our method indeed identifies the most energetic initial perturbations that are spatially compact. This work was supported by Office of Naval Research through Grant Number N00014-15-1-2522.

A phase II trial of androgen deprivation therapy (ADT) plus chemotherapy as initial treatment for local failures or advanced prostate cancer.

Science.gov (United States)

Amato, Robert; Stepankiw, Mika; Gonzales, Patricia

2013-06-01

Long-term hormonal ablation in prostate cancer is associated with decreased overall health and quality of life. Few reports emphasized the role of chemotherapy in the management of early stage prostate cancer. This study analyzed the safety and efficacy of androgen deprivation therapy (ADT) plus chemotherapy as initial treatment for patients identified as local failures or not eligible for prostatectomy or radiation therapy due to advanced disease presentation. Enrolled patients received ADT in the form of leuprolide every 12 weeks for 24 months with bicalutamide initiating after the completion of chemotherapy. Chemotherapy consisted of ketoconazole and doxorubicin for weeks 1, 3, and 5 and estramustine and docetaxel and for weeks 2, 4 and 6. During weeks 7 and 8, no treatment was received. Forty-six patients were enrolled, and forty-five patients were evaluable. Median progression-free survival (PFS) was 23.4 months. Median overall survival (OS) was 53.7 months. Out of 45 patients with measurable disease, 22 patients had an objective response: 9 patients achieved a complete response; 2 patients achieved a partial response; 10 patients achieved stable disease. Frequent grade 3 adverse events included elevated ALT (17 %), hypokalemia (13 %), and hypophosphatemia (13 %). Grade 4 adverse events were rare and included low bicarbonate (2 %), hypokalemia (2 %), leukocytopenia (2 %), and neutropenia (2 %). The treatment demonstrated clinical benefit in all patient subsets with minimal reversible treatment-related adverse events. Subgroup analysis suggests that having prior local therapy resulted in greater PFS and OS.

Initial operations in local nuclear emergency response headquarter

International Nuclear Information System (INIS)

2012-06-01

As a result of the Fukushima nuclear accident due to the Great East Japan Earthquake and the tsunami that occurred thereafter, local nuclear emergency response headquarters (local headquarters) was set up at off-site center (OFC). However, several obstacles such as the collapse of means of communication resulting from severed communication lines, food and fuel shortage resulting from stagnant physical distribution, and increasing radiation dose around the center significantly restricted originally intended operation of local headquarters. In such severe situation, the personnel gathered at the OFC from the government, local public bodies and electric companies from March 11 to 15 acted without sufficient food, sleep or rest and did all they could against successively occurring unexpected challenges by using limited means of communication. However, issues requiring further consideration were activities of each functional group, location of OFC and the functions of equipment, machines and materials and reflecting the consideration results into future protective measures and revision of the manual for nuclear emergency response were greatly important. This report described investigated results on initial operations in local headquarters such as situation of activities conducted by local headquarters and operations at functional groups. (T. Tanaka)

Facilitating Follow-up of LIGO–Virgo Events Using Rapid Sky Localization

Energy Technology Data Exchange (ETDEWEB)

Chen, Hsin-Yu [Department of Astronomy and Astrophysics and Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637 (United States); Holz, Daniel E. [Enrico Fermi Institute, Department of Physics, Department of Astronomy and Astrophysics, and Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637 (United States)

2017-05-10

We discuss an algorithm for accurate and very low-latency (<1 s) localization of gravitational-wave (GW) sources using only the relative times of arrival, relative phases, and relative signal-to-noise ratios for pairs of detectors. The algorithm is independent of distances and masses to leading order, and can be generalized to all discrete (as opposed to stochastic and continuous) sources detected by ground-based detector networks. Our approach is similar to that of BAYESTAR with a few modifications, which result in increased computational efficiency. For the LIGO two-detector configuration (Hanford+Livingston) operating in O1 we find a median 50% (90%) localization of 143 deg{sup 2} (558 deg{sup 2}) for binary neutron stars. We use our algorithm to explore the improvement in localization resulting from loud events, finding that the loudest out of the first 4 (or 10) events reduces the median sky-localization area by a factor of 1.9 (3.0) for the case of two GW detectors, and 2.2 (4.0) for three detectors. We also consider the case of multi-messenger joint detections in both the gravitational and the electromagnetic radiation, and show that joint localization can offer significant improvements (e.g., in the case of LIGO and Fermi /GBM joint detections). We show that a prior on the binary inclination, potentially arising from GRB observations, has a negligible effect on GW localization. Our algorithm is simple, fast, and accurate, and may be of particular utility in the development of multi-messenger astronomy.

Abnormal global and local event detection in compressive sensing domain

Directory of Open Access Journals (Sweden)

Tian Wang

2018-05-01

Full Text Available Abnormal event detection, also known as anomaly detection, is one challenging task in security video surveillance. It is important to develop effective and robust movement representation models for global and local abnormal event detection to fight against factors such as occlusion and illumination change. In this paper, a new algorithm is proposed. It can locate the abnormal events on one frame, and detect the global abnormal frame. The proposed algorithm employs a sparse measurement matrix designed to represent the movement feature based on optical flow efficiently. Then, the abnormal detection mission is constructed as a one-class classification task via merely learning from the training normal samples. Experiments demonstrate that our algorithm performs well on the benchmark abnormal detection datasets against state-of-the-art methods.

76 FR 36308 - Special Local Regulation for Marine Events; Temporary Change of dates for Recurring Marine Events...

Science.gov (United States)

2011-06-22

... hour, make special local regulations necessary. However, the Coast Guard will provide advance... dangers posed by hydroplane speed boats, operating in speeds excess of 150 miles per hour, make special... includes but is not limited to sail boat regattas, boat parades, power boat racing, swimming events, crew...

The Progress in Localization Initiatives in PDC, BST

International Nuclear Information System (INIS)

Rosli Darmawan; Hasni Hassan; Anwar Abdul Rahman

2011-01-01

Nuclear Malaysia has been established since 1972. It has evolves from laying the foundation for infrastructure and human resources in nuclear technology; research and development in nuclear applications; producing new products and prototypes; and finally, transferring the products and technology to the end users such as the industry and communities. While Nuclear Malaysia has been able to develop various nuclear applications, there are areas which have been left behind. Most of the facilities and instruments for nuclear Research and Development are imported. Although Nuclear Malaysia has been able to operate and maintain the facilities, there are occasions where the foreign experts and components need to be sought for. This dependency on foreign technology has cost Nuclear Malaysia a lot, especially in the maintenance and procurement of new instruments and spare parts. To reduce this dependency, some localization initiatives have been conducted by various groups in Nuclear Malaysia. This paper discusses the recent progress and achievement of localization initiatives undertaken by PDC on the related technology which has reduced the dependency on foreign experts and technology. (author)

Identification and localization of neutrino events in the OPERA detector

International Nuclear Information System (INIS)

Heritier, C.

2004-07-01

The OPERA experiment is designed for the appearance search of ν μ → ν τ oscillations in the parameters indicated by the atmospheric neutrino anomaly. To prove the appearance of ν τ at 732 km from the CERN, an hybrid detector is under construction at the Gran Sasso laboratory. The target, composed by bricks made of lead plates and emulsion sheets, allows the direct observation of the τ lepton produced in ν τ charged current interactions. The tracking, the localization of neutrino events in the target and the muon identification are allowed by trackers located inside the target (scintillators) and in the spectrometer following the target (RPC). The development of algorithms, based on electronic detectors, is necessary to identify the neutrino interaction and to locate the bricks where the interaction occurred. A classification of neutrino events is performed using the identification of the muon produced in ν μ CC and ν τ CC with τ → μ decay. This classification is optimised with tracking informations and also with topological and calorimetric parameters which describe the nature of the interaction (quasi-elastic, deep inelastic); the algorithm of the localization of neutrino event is performed for each category. A tridimensional brick probability map is built and can be exploited to implement sophisticated extraction brick strategies. To conclude, a feasibility study of a test beam experiment OPERETTE is presented. The project was to install a similar OPERA detector in the COMPASS neutrino beam, in the CERN North Area. It was a good opportunity to prepare OPERA for the scanning emulsion films with neutrino events and to test the analysis procedures. (author)

State and Local Initiatives: Your Bridge to Renewable Energy and Energy Efficiency Resources (Brochure)

International Nuclear Information System (INIS)

Epstein, K.

2001-01-01

A brochure for local and state policymakers, informing them about the State and Local Initiatives team at the National Renewable Energy Laboratory. The brochure outlines the benefits of using renewables and energy efficiency, the benefits of using the State and Local Initiatives team as a liaison to the wealth of information at NREL, and some of the services and resources available

Event localization in bulk scintillator crystals using coded apertures

Energy Technology Data Exchange (ETDEWEB)

Ziock, K.P. [Oak Ridge National Laboratory, Oak Ridge, TN (United States); Department of Physics and Astronomy, University of Tennessee, Knoxville, TN (United States); Braverman, J.B. [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN (United States); Fabris, L.; Harrison, M.J.; Hornback, D.; Newby, J. [Oak Ridge National Laboratory, Oak Ridge, TN (United States)

2015-06-01

The localization of radiation interactions in bulk scintillators is generally limited by the size of the light distribution at the readout surface of the crystal/light-pipe system. By finding the centroid of the light spot, which is typically of order centimeters across, practical single-event localization is limited to ~2 mm/cm of crystal thickness. Similar resolution can also be achieved for the depth of interaction by measuring the size of the light spot. Through the use of near-field coded-aperture techniques applied to the scintillation light, light transport simulations show that for 3-cm-thick crystals, more than a five-fold improvement (millimeter spatial resolution) can be achieved both laterally and in event depth. At the core of the technique is the requirement to resolve the shadow from an optical mask placed in the scintillation light path between the crystal and the readout. In this paper, experimental results are presented that demonstrate the overall concept using a 1D shadow mask, a thin-scintillator crystal and a light pipe of varying thickness to emulate a 2.2-cm-thick crystal. Spatial resolutions of ~1 mm in both depth and transverse to the readout face are obtained over most of the crystal depth.

Event localization in bulk scintillator crystals using coded apertures

International Nuclear Information System (INIS)

Ziock, K.P.; Braverman, J.B.; Fabris, L.; Harrison, M.J.; Hornback, D.; Newby, J.

2015-01-01

The localization of radiation interactions in bulk scintillators is generally limited by the size of the light distribution at the readout surface of the crystal/light-pipe system. By finding the centroid of the light spot, which is typically of order centimeters across, practical single-event localization is limited to ~2 mm/cm of crystal thickness. Similar resolution can also be achieved for the depth of interaction by measuring the size of the light spot. Through the use of near-field coded-aperture techniques applied to the scintillation light, light transport simulations show that for 3-cm-thick crystals, more than a five-fold improvement (millimeter spatial resolution) can be achieved both laterally and in event depth. At the core of the technique is the requirement to resolve the shadow from an optical mask placed in the scintillation light path between the crystal and the readout. In this paper, experimental results are presented that demonstrate the overall concept using a 1D shadow mask, a thin-scintillator crystal and a light pipe of varying thickness to emulate a 2.2-cm-thick crystal. Spatial resolutions of ~1 mm in both depth and transverse to the readout face are obtained over most of the crystal depth

Struggle over energy transition in Berlin: How do grassroots initiatives affect local energy policy-making?

International Nuclear Information System (INIS)

Blanchet, Thomas

2015-01-01

This paper examines the growing role of grassroots initiatives in the governance of urban energy systems. In recent years, research has increasingly underlined the potential for sustainable innovation of community-led bottom-up actions but has at the same time underestimated their potential impact on the governance of energy systems. Based on a strategic action field framework (SAF), this paper analyses the conflicts over the remunicipalisation of Berlin's electricity grid and investigates the creation and strategic development of two grassroots initiatives as well as their interaction with the local government and the established grid operator. We argue that grassroots initiatives have an important impact on the local energy system, not just through their influence on the implementation of local energy policy but above all by their framing of a specific vision of a local energy transition. The paper discusses the scope and limits of such initiatives in an urban context. - Highlights: • Grassroots initiatives as actors with countervailing power in local energy policy. • They increase citizens' awareness and impact the action of the local government. • Grids as objects of struggle between competing visions of energy transition. • Urban context is both a resource and a constraint for grassroots initiatives action

Identification of human-induced initiating events in the low power and shutdown operation using the commission error search and assessment method

Energy Technology Data Exchange (ETDEWEB)

Kim, Yong Chan; Kim, Jong Hyun [KEPCO International Nuclear Graduate School (KINGS), Ulsan (Korea, Republic of)

2015-03-15

Human-induced initiating events, also called Category B actions in human reliability analysis, are operator actions that may lead directly to initiating events. Most conventional probabilistic safety analyses typically assume that the frequency of initiating events also includes the probability of human-induced initiating events. However, some regulatory documents require Category B actions to be specifically analyzed and quantified in probabilistic safety analysis. An explicit modeling of Category B actions could also potentially lead to important insights into human performance in terms of safety. However, there is no standard procedure to identify Category B actions. This paper describes a systematic procedure to identify Category B actions for low power and shutdown conditions. The procedure includes several steps to determine operator actions that may lead to initiating events in the low power and shutdown stages. These steps are the selection of initiating events, the selection of systems or components, the screening of unlikely operating actions, and the quantification of initiating events. The procedure also provides the detailed instruction for each step, such as operator's action, information required, screening rules, and the outputs. Finally, the applicability of the suggested approach is also investigated by application to a plant example.

Event-By-Event Initial Conditions for Heavy Ion Collisions

International Nuclear Information System (INIS)

Rose, S; Fries, R J

2017-01-01

The early time dynamics of heavy ion collisions can be described by classical fields in an approximation of Quantum ChromoDynamics (QCD) called Color Glass Condensate (CGC). Monte-Carlo sampling of the color charge for the incoming nuclei are used to calculate their classical gluon fields. Following the recent work by Chen et al. we calculate the energy momentum tensor of those fields at early times in the collision event-by-event. This can then be used for subsequent hydrodynamic evolution of the single events. (paper)

Event-By-Event Initial Conditions for Heavy Ion Collisions

Science.gov (United States)

Rose, S.; Fries, R. J.

2017-04-01

The early time dynamics of heavy ion collisions can be described by classical fields in an approximation of Quantum ChromoDynamics (QCD) called Color Glass Condensate (CGC). Monte-Carlo sampling of the color charge for the incoming nuclei are used to calculate their classical gluon fields. Following the recent work by Chen et al. we calculate the energy momentum tensor of those fields at early times in the collision event-by-event. This can then be used for subsequent hydrodynamic evolution of the single events.

Identification of initiating events using a master logic diagram in low-power and shutdown PSA for nuclear power plant

International Nuclear Information System (INIS)

Han, S. J.; Park, J. H.; Kim, T. W.; Ha, J. J.

2003-01-01

It is necessary to apply a formal technique instead of an empirical technique in the identification of initiating events for Low Power and ShutDown (LPSD) Probabilistic Safety Assessment (PSA) of Nuclear Power Plant (NPP). The present study focuses on the examination of Master Logic Diagram (MLD) technique as a formal technique in the identification of initiating events. The MLD technique is a deductive tool using top-down approach for the formal and logical indentification of initiating events. The present study modified the MLD used in the full power PSA considering the characteristics of LPSD operation. The modified MLD introduced a systematic formation in decomposition process of which the MLD for full power PSA lacked. The modified MLD was able to identify initiating events systematic and logical. However, the formal techniques including the MLD have a limitation for precisely identifying all of the initiating events. In order to overcome this limitation, it is necessary to combine it with an empirical technique. We expect that the modified MLD can be used in an upgrade of the current LPSD PSAs

Identification of Common Cause Initiating Events Using the NEA IRS Database. Rev 0

International Nuclear Information System (INIS)

Kulig, Maciej; Tomic, Bojan; Nyman, R alph

2007-02-01

The study presented in this report is a continuation of work conducted for SKI in 1998 on the identification of Common Cause Initiators (CCIs) based on operational events documented in the NEA Incident Reporting System (IRS). Based on the new operational experience accumulated in IRS in the period 1995-2006, the project focused on the identification of new CCI events. An attempt was also made to compare the observations made in the earlier study with the results of the current work. The earlier study and the current project cover the events reported in the IRS database with the incident date in the period from 01.01.1980 to 15.11.2006. The review of the NEA IRS database conducted within this project generated a sample of events that provides insights regarding the Common Cause Initiators (CCIs). This list includes certain number of 'real' CCIs but also potential CCIs and other events that provide insights on potential dependency mechanisms. Relevant characteristics of the events were analysed in the context of CCIs. This evaluation was intended to investigate the importance of the CCI issue and also to provide technical insights that could help in the modelling the CCIs in PSAs. The analysis of operational events provided useful engineering insights regarding the potential dependencies that may originate CCIs. Some indications were also obtained on the plant SSCs/areas that are susceptible to common cause failures. Direct interrelations between the accident mitigation systems through common support systems, which can originate a CCI, represent a dominant dependency mechanism involved in the CCI events. The most important contributors of this type are electrical power supply systems and I-and-C systems. Area-related events (fire, flood, water spray), external hazards (lightning, high wind or cold weather) and transients (water hammer, electrical transients both internal and external) have also been found to be important sources of dependency that may originate CCIs

Identification of Common Cause Initiating Events Using the NEA IRS Database. Rev 0

Energy Technology Data Exchange (ETDEWEB)

Kulig, Maciej; Tomic, Bojan (Enconet Consulting, Vienna (Austria)); Nyman, Ralph (Swedish Nuclear Power Inspectorate, Stockholm (Sweden))

2007-02-15

The study presented in this report is a continuation of work conducted for SKI in 1998 on the identification of Common Cause Initiators (CCIs) based on operational events documented in the NEA Incident Reporting System (IRS). Based on the new operational experience accumulated in IRS in the period 1995-2006, the project focused on the identification of new CCI events. An attempt was also made to compare the observations made in the earlier study with the results of the current work. The earlier study and the current project cover the events reported in the IRS database with the incident date in the period from 01.01.1980 to 15.11.2006. The review of the NEA IRS database conducted within this project generated a sample of events that provides insights regarding the Common Cause Initiators (CCIs). This list includes certain number of 'real' CCIs but also potential CCIs and other events that provide insights on potential dependency mechanisms. Relevant characteristics of the events were analysed in the context of CCIs. This evaluation was intended to investigate the importance of the CCI issue and also to provide technical insights that could help in the modelling the CCIs in PSAs. The analysis of operational events provided useful engineering insights regarding the potential dependencies that may originate CCIs. Some indications were also obtained on the plant SSCs/areas that are susceptible to common cause failures. Direct interrelations between the accident mitigation systems through common support systems, which can originate a CCI, represent a dominant dependency mechanism involved in the CCI events. The most important contributors of this type are electrical power supply systems and I-and-C systems. Area-related events (fire, flood, water spray), external hazards (lightning, high wind or cold weather) and transients (water hammer, electrical transients both internal and external) have also been found to be important sources of dependency that may

77 FR 18984 - Special Local Regulation for Marine Events; Yorktown Parade of Sail, York River; Yorktown, VA

Science.gov (United States)

2012-03-29

...-AA08 Special Local Regulation for Marine Events; Yorktown Parade of Sail, York River; Yorktown, VA... proposes to establish special local regulation during the Yorktown Parade of Sail, a parade of five tall... sponsor the ``Yorktown Parade of Sail'' on the waters of York River. The event will consist of...

Towards Optimal Event Detection and Localization in Acyclic Flow Networks

KAUST Repository

Agumbe Suresh, Mahima

2012-01-03

Acyclic flow networks, present in many infrastructures of national importance (e.g., oil & gas and water distribution systems), have been attracting immense research interest. Existing solutions for detecting and locating attacks against these infrastructures, have been proven costly and imprecise, especially when dealing with large scale distribution systems. In this paper, to the best of our knowledge for the first time, we investigate how mobile sensor networks can be used for optimal event detection and localization in acyclic flow networks. Sensor nodes move along the edges of the network and detect events (i.e., attacks) and proximity to beacon nodes with known placement in the network. We formulate the problem of minimizing the cost of monitoring infrastructure (i.e., minimizing the number of sensor and beacon nodes deployed), while ensuring a degree of sensing coverage in a zone of interest and a required accuracy in locating events. We propose algorithms for solving these problems and demonstrate their effectiveness with results obtained from a high fidelity simulator.

Local instability driving extreme events in a pair of coupled chaotic electronic circuits

Science.gov (United States)

de Oliveira, Gilson F.; Di Lorenzo, Orlando; de Silans, Thierry Passerat; Chevrollier, Martine; Oriá, Marcos; Cavalcante, Hugo L. D. de Souza

2016-06-01

For a long time, extreme events happening in complex systems, such as financial markets, earthquakes, and neurological networks, were thought to follow power-law size distributions. More recently, evidence suggests that in many systems the largest and rarest events differ from the other ones. They are dragon kings, outliers that make the distribution deviate from a power law in the tail. Understanding the processes of formation of extreme events and what circumstances lead to dragon kings or to a power-law distribution is an open question and it is a very important one to assess whether extreme events will occur too often in a specific system. In the particular system studied in this paper, we show that the rate of occurrence of dragon kings is controlled by the value of a parameter. The system under study here is composed of two nearly identical chaotic oscillators which fail to remain in a permanently synchronized state when coupled. We analyze the statistics of the desynchronization events in this specific example of two coupled chaotic electronic circuits and find that modifying a parameter associated to the local instability responsible for the loss of synchronization reduces the occurrence of dragon kings, while preserving the power-law distribution of small- to intermediate-size events with the same scaling exponent. Our results support the hypothesis that the dragon kings are caused by local instabilities in the phase space.

Local Governments Supporting Local Energy Initiatives: Lessons from the Best Practices of Saerbeck (Germany) and Lochem (The Netherlands)

NARCIS (Netherlands)

Hoppe, Thomas; Graf, Antonia; Warbroek, Wynzen Douwe Beau; Lammers, Imke; Lepping, Isabella

2015-01-01

The social dimension of the transition to a low carbon economy is a key challenge to cities. The establishment of local energy initiatives (LEIs) has recently been attracting attention. It is of great importance to draw lessons from best practices when LEIs have been facilitated by local governments

An Initiating-Event Analysis for PSA of Hanul Units 3 and 4: Results and Insights

International Nuclear Information System (INIS)

Kim, Dong-San; Park, Jin Hee

2015-01-01

As a part of the PSA, an initiating-event (IE) analysis was newly performed by considering the current state of knowledge and the requirements of the ASME/ANS probabilistic risk assessment (PRA) standard related to IE analysis. This paper describes the methods of, results and some insights from the IE analysis for the PSA of the Hanul units 3 and 4. In this study, as a part of the PSA for the Hanul units 3 and 4, an initiating-event (IE) analysis was newly performed by considering the current state of knowledge and the requirements of the ASME/ANS probabilistic risk assessment (PRA) standard. In comparison with the previous IE analysis, this study performed a more systematic and detailed analysis to identify potential initiating events, and calculated the IE frequencies by using the state-of-the-art methods and the latest data. As a result, not a few IE frequencies are quite different from the previous frequencies, which can change the major accident sequences obtained from the quantification of the PSA model

Initiation of Meiotic Recombination in Mammals

Directory of Open Access Journals (Sweden)

Rajeev Kumar

2010-12-01

Full Text Available Meiotic recombination is initiated by the induction of programmed DNA double strand breaks (DSBs. DSB repair promotes homologous interactions and pairing and leads to the formation of crossovers (COs, which are required for the proper reductional segregation at the first meiotic division. In mammals, several hundred DSBs are generated at the beginning of meiotic prophase by the catalytic activity of SPO11. Currently it is not well understood how the frequency and timing of DSB formation and their localization are regulated. Several approaches in humans and mice have provided an extensive description of the localization of initiation events based on CO mapping, leading to the identification and characterization of preferred sites (hotspots of initiation. This review presents the current knowledge about the proteins known to be involved in this process, the sites where initiation takes place, and the factors that control hotspot localization.

The Effect of Local Events to Rural Tourism as a Recreational Activity

Directory of Open Access Journals (Sweden)

Elif Zeynep ÖZER

2014-08-01

Full Text Available Recreation is the activities that person attends voluntarily in his/her spare time to refreshing, relaxing and motivation. Activities that are made in rural area are option for recreational activities. There is an increase in consumer demand for rural tour ism as an alternative tourism option. Participants get a chance to know different cultural structures and chance to see natural beauties by attending rural activities. Events that are performed with attendees form different destinations are support area fr om economy, development and advertising point of view. Objective of this work is making contribution to development rural tourism and recreational activities by defining the effect of local events to rural tourism as a recreational activity. In this work, the effect of participation of recreational tourism activities to rural tourism is investigated. Data that is required is gathered by semi structured interview technique. The result of this work has a potential to use a resource to lead event managers. Thi s work also has a potential to use a resource for studies that are related to recreation tourism, local activities and rural tourism.

Signaling events during initiation of arbuscular mycorrhizal symbiosis.

Science.gov (United States)

Schmitz, Alexa M; Harrison, Maria J

2014-03-01

Under nutrient-limiting conditions, plants will enter into symbiosis with arbuscular mycorrhizal (AM) fungi for the enhancement of mineral nutrient acquisition from the surrounding soil. AM fungi live in close, intracellular association with plant roots where they transfer phosphate and nitrogen to the plant in exchange for carbon. They are obligate fungi, relying on their host as their only carbon source. Much has been discovered in the last decade concerning the signaling events during initiation of the AM symbiosis, including the identification of signaling molecules generated by both partners. This signaling occurs through symbiosis-specific gene products in the host plant, which are indispensable for normal AM development. At the same time, plants have adapted complex mechanisms for avoiding infection by pathogenic fungi, including an innate immune response to general microbial molecules, such as chitin present in fungal cell walls. How it is that AM fungal colonization is maintained without eliciting a defensive response from the host is still uncertain. In this review, we present a summary of the molecular signals and their elicited responses during initiation of the AM symbiosis, including plant immune responses and their suppression. © 2014 Institute of Botany, Chinese Academy of Sciences.

Supervisor Localization: A Top-Down Approach to Distributed Control of Discrete-Event Systems

International Nuclear Information System (INIS)

Cai, K.; Wonham, W. M.

2009-01-01

A purely distributed control paradigm is proposed for discrete-event systems (DES). In contrast to control by one or more external supervisors, distributed control aims to design built-in strategies for individual agents. First a distributed optimal nonblocking control problem is formulated. To solve it, a top-down localization procedure is developed which systematically decomposes an external supervisor into local controllers while preserving optimality and nonblockingness. An efficient localization algorithm is provided to carry out the computation, and an automated guided vehicles (AGV) example presented for illustration. Finally, the 'easiest' and 'hardest' boundary cases of localization are discussed.

Seeking for toroidal event horizons from initially stationary BH configurations

International Nuclear Information System (INIS)

Ponce, Marcelo; Lousto, Carlos; Zlochower, Yosef

2011-01-01

We construct and evolve non-rotating vacuum initial data with a ring singularity, based on a simple extension of the standard Brill-Lindquist multiple BH initial data, and search for event horizons with spatial slices that are toroidal when the ring radius is sufficiently large. While evolutions of the ring singularity are not numerically feasible for large radii, we find some evidence, based on configurations of multiple BHs arranged in a ring, that this configuration leads to singular limit where the horizon width has zero size, possibly indicating the presence of a naked singularity, when the radius of the ring is sufficiently large. This is in agreement with previous studies that have found that there is no apparent horizon surrounding the ring singularity when the ring's radius is larger than about twice its mass.

Estimation of initiating event distribution at nuclear power plants by Bayesian procedure

International Nuclear Information System (INIS)

Chen Guangming

1995-01-01

Initiating events at nuclear power plants such as human errors or components failures may lead to a nuclear accident. The study of the frequency of these events or the distribution of the failure rate is necessary in probabilistic risk assessment for nuclear power plants. This paper presents Bayesian modelling methods for the analysis of the distribution of the failure rate. The method can also be utilized in other related fields especially where the data is sparse. An application of the Bayesian modelling in the analysis of distribution of the time to recover Loss of Off-Site Power ( LOSP) is discussed in the paper

Factors controlling the initiation of Snowball Earth events

Science.gov (United States)

Voigt, A.

2012-12-01

During the Neoproterozoic glaciations tropical continents were covered by active glaciers that extended down to sea level. To explain these glaciers, the Snowball Earth hypothesis assumes that oceans were completely sea-ice covered during these glaciation, but there is an ongoing debate whether or not some regions of the tropical oceans remained open. In this talk, I will describe past and ongoing climate modelling activities with the comprehensive coupled climate model ECHAM5/MPI-OM that identify and compare factors that control the initiation of Snowball Earth events. I first show that shifting the continents from their present-day location to their Marinoan (635 My BP) low-latitude location increases the planetary albedo, cools the climate, and thereby allows Snowball Earth initiation at higher levels of total solar irradiance and atmospheric CO2. I then present simulations with successively lowered bare sea-ice albedo, disabled sea-ice dynamics, and switched-off ocean heat transport. These simulations show that both lowering the bare sea-ice albedo and disabling sea-ice dynamics increase the critical sea-ice cover in ECHAM5/MPI-OM, but sea-ice dynamics due to strong equatorward sea-ice transport have a much larger influence on the critical CO2. Disabling sea-ice transport allows a state with sea-ice margin at 10 deg latitude by virtue of the Jormungand mechanism. The accumulation of snow on land, in combination with tropical land temperatures below or close to freezing, suggests that tropical land glaciers could easily form in such a state. However, in contrast to aquaplanet simulations without ocean heat transport, there is no sign of a Jormungand hysteresis in the coupled simulations. Ocean heat transport is not responsible for the lack of a Jormungand hysteresis in the coupled simulations. By relating the above findings to previous studies, I will outline promising future avenues of research on the initiation of Snowball Earth events. In particular, an

Des initiatives locales européennes pour atteindre le facteur 4 ?

Directory of Open Access Journals (Sweden)

Elsa Mor

2011-03-01

Full Text Available Dans un contexte d’urgence climatique et de pics énergétiques, la dimension locale s’avère être une échelle stratégique pour relever le défi du facteur 4. C’est ce que nous tenterons de questionner au cœur de cet article. Nous examinerons les freins et les leviers que rencontrent les initiatives locales en Europe, en matière de politiques sectorielles, énergétiques et climatiques, ainsi que de gouvernance, en nous appuyant d’exemples précurseurs.In a climate emergency and peak oil context, the local dimension proves to be a strategical scale to take up the challenge of factor 4. It is what we will try to question in this article. We will examine brakes and levers which meet the local initiatives in Europe, in sectoral, energy-climate policies and governance, by leaning of forerunners examples.

Mesoscale and Local Scale Evaluations of Quantitative Precipitation Estimates by Weather Radar Products during a Heavy Rainfall Event

Directory of Open Access Journals (Sweden)

Basile Pauthier

2016-01-01

Full Text Available A 24-hour heavy rainfall event occurred in northeastern France from November 3 to 4, 2014. The accuracy of the quantitative precipitation estimation (QPE by PANTHERE and ANTILOPE radar-based gridded products during this particular event, is examined at both mesoscale and local scale, in comparison with two reference rain-gauge networks. Mesoscale accuracy was assessed for the total rainfall accumulated during the 24-hour event, using the Météo France operational rain-gauge network. Local scale accuracy was assessed for both total event rainfall and hourly rainfall accumulations, using the recently developed HydraVitis high-resolution rain gauge network Evaluation shows that (1 PANTHERE radar-based QPE underestimates rainfall fields at mesoscale and local scale; (2 both PANTHERE and ANTILOPE successfully reproduced the spatial variability of rainfall at local scale; (3 PANTHERE underestimates can be significantly improved at local scale by merging these data with rain gauge data interpolation (i.e., ANTILOPE. This study provides a preliminary evaluation of radar-based QPE at local scale, suggesting that merged products are invaluable for applications at very high resolution. The results obtained underline the importance of using high-density rain-gauge networks to obtain information at high spatial and temporal resolution, for better understanding of local rainfall variation, to calibrate remotely sensed rainfall products.

Preparing for novel versus familiar events: shifts in global and local processing

NARCIS (Netherlands)

Förster, J.; Liberman, N.; Shapiro, O.

2009-01-01

Six experiments examined whether novelty versus familiarity influences global versus local processing styles. Novelty and familiarity were manipulated by either framing a task as new versus familiar or by asking participants to reflect upon novel versus familiar events prior to the task (i.e.,

Local, organic food initiatives and their potentials for transforming the conventional food system

Directory of Open Access Journals (Sweden)

Geir Lieblein

2005-05-01

Full Text Available L’objectif de cet article est de discuter l’importance des initiatives locales dans la distribution de produits biologiques. Le sujet est abordé d’une part en fonction de la relation entre ce type d’initiatives et le système agroalimentaire conventionnel et d’autre part en fonction de la possibilité du développement d’un système agroalimentaire plus durable. Basé sur trois études scandinaves, concernant des produits biologiques en Norvège et au Danemark, cet article souligne le fait que les différents acteurs intreviewés jouent à la fois sur le tableau du local et du biologique et sur le tableau du conventionnel. En dépit de différences structurelles distinctes, les deux systèmes, et les conventions qui leur sont rattachées, s’influencent mutuellement. Afin de mettre au point une agriculture plus durable, il semble donc important de mettre en valeur le fondement global de l’agriculture écologique, qui repose non seulement sur des valeurs biologiques et locales, mais encore sur des aspects économiques, sociaux et culturels qui doivent être pris en considération.The aim of this article is to discuss the importance of local initiatives for distribution of organic food. This subject is discussed both in relation to how such initiatives may affect the overall conventional food system and the possible implications for development of a more sustainable food system. The article is based on findings from three different cases of local, organic food in Norway and Denmark. We found that actors within the cases are both involved with local, organic food initiatives and at the same time part of the overall conventional food system. Even though there are distinctive structural differences between these distribution systems, they mutually affect each other. This means that conventions normally associated with local, organic food systems may ‘rub off’ to the conventional food system and vice versa. In order to develop

Local meanings of a sport mega-event's legacies : Stories from a South African urban neighbourhood

NARCIS (Netherlands)

Waardenburg, Maikel; van den Bergh, Marjolein; van Eekeren, Frank

2015-01-01

Studies on sport mega-events and their legacies often seem only loosely connected to local experiences. Stories on sport mega-event legacy appear as a setting-the-scene or function as a reference to illustrate specific types of legacy. However, stories themselves are never the primary focus in these

Local French Food Initiatives in Practice: The Emergence of a Social Movement

Directory of Open Access Journals (Sweden)

Angela Giovanangeli

2013-07-01

Full Text Available This article analyses the development of local food systems from a social movement perspective. It examines the case study of a farm market located in France and considers whether and how local initiatives in food distribution can be viewed as a social movement, using social theory as the conceptual framework.

77 FR 23601 - Special Local Regulations and Safety Zones; Recurring Events in Northern New England

Science.gov (United States)

2012-04-20

... England AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The Coast Guard is updating special local... provide the event name, sponsor, and type, as well as approximate dates and locations of the events. The... can better evaluate its effects on them and participate in the rulemaking. If the rule affects your...

Supervisor localization a top-down approach to distributed control of discrete-event systems

CERN Document Server

Cai, Kai

2016-01-01

This monograph presents a systematic top-down approach to distributed control synthesis of discrete-event systems (DES). The approach is called supervisor localization; its essence is the allocation of external supervisory control action to individual component agents as their internal control strategies. The procedure is: first synthesize a monolithic supervisor, to achieve globally optimal and nonblocking controlled behavior, then decompose the monolithic supervisor into local controllers, one for each agent. The collective behavior of the resulting local controllers is identical to that achieved by the monolithic supervisor. The basic localization theory is first presented in the Ramadge–Wonham language-based supervisory control framework, then demonstrated with distributed control examples of multi-robot formations, manufacturing systems, and distributed algorithms. An architectural approach is adopted to apply localization to large-scale DES; this yields a heterarchical localization procedure, which is...

Salvage treatment for local or local-regional recurrence after initial breast conservation treatment with radiation for ductal carcinoma in situ

NARCIS (Netherlands)

Solin, Lawrence J.; Fourquet, Alain; Vicini, Frank A.; Taylor, Marie; Haffty, Bruce; Strom, Eric A.; Wai, Elaine; Pierce, Lori J.; Marks, Lawrence B.; Bartelink, Harry; Campana, Francois; McNeese, Marsha D.; Jhingran, Anuja; Olivotto, Ivo A.; Bijker, Nina; Hwang, Wei-Ting

2005-01-01

The present study evaluated the outcome of salvage treatment for women with local or local-regional recurrence after initial breast conservation treatment with radiation for mammographically detected ductal carcinoma in situ (DCIS; intraductal carcinoma) of the breast. The study cohort consisted of

A code for transcription initiation in mammalian genomes

DEFF Research Database (Denmark)

Frith, Martin C.; Valen, Eivind Dale; Krogh, Anders

2007-01-01

that initiation events are clustered on the chromosomes at multiple scales - clusters within clusters - indicating multiple regulatory processes. Within the smallest of such clusters, which can be interpreted as core promoters, the local DNA sequence predicts the relative transcription start usage of each...... of large- and small-scale effects: the selection of transcription start sites is largely governed by the local DNA sequence, whereas the transcriptional activity of a locus is regulated at a different level; it is affected by distal features or events such as enhancers and chromatin remodeling....

75 FR 29889 - Special Local Regulation for Marine Event; 2010 International Cup Regatta, Pasquotank River...

Science.gov (United States)

2010-05-28

...-AA08 Special Local Regulation for Marine Event; 2010 International Cup Regatta, Pasquotank River... traffic in a portion of the Pasquotank River, near Elizabeth City, NC, during the 2010 International Cup... event in 33 CFR 100.501 and 33 CFR Table to Sec. 100.501, No. 54. On June 5 and 6, 2010, Carolina Cup...

78 FR 59230 - Special Local Regulations; Annual Marine Events on the Colorado River, Between Davis Dam...

Science.gov (United States)

2013-09-26

... period via the Local Notice to Mariners and local advertising by the event sponsor. If the Captain of the... enforced for the full duration stated on this notice, he or she may use a Broadcast Notice to Mariners or...

Physical mechanism of initial breakdown pulses and narrow bipolar events in lightning discharges

Science.gov (United States)

Silva, Caitano L.; Pasko, Victor P.

2015-05-01

To date the true nature of initial breakdown pulses (IBPs) and narrow bipolar events (NBEs) in lightning discharges remains a mystery. Recent experimental evidence has correlated IBPs to the initial development of lightning leaders inside the thundercloud. NBE wideband waveforms resemble classic IBPs in both amplitude and duration. Most NBEs are quite peculiar in the sense that very frequently they occur in isolation from other lightning processes. The remaining fraction, 16% of positive polarity NBEs, according to Wu et al. (2014), happens as the first event in an otherwise regular intracloud lightning discharge. These authors point out that the initiator type of NBEs has no difference with other NBEs that did not start lightning, except for the fact that they occur deeper inside the thunderstorm (i.e., at lower altitudes). In this paper, we propose a new physical mechanism to explain the source of both IBPs and NBEs. We propose that IBPs and NBEs are the electromagnetic transients associated with the sudden (i.e., stepwise) elongation of the initial negative leader extremity in the thunderstorm electric field. To demonstrate our hypothesis a novel computational/numerical model of the bidirectional lightning leader tree is developed, consisting of a generalization of electrostatic and transmission line approximations found in the literature. Finally, we show how the IBP and NBE waveform characteristics directly reflect the properties of the bidirectional lightning leader (such as step length, for example) and amplitude of the thunderstorm electric field.

Modelling machine ensembles with discrete event dynamical system theory

Science.gov (United States)

Hunter, Dan

1990-01-01

Discrete Event Dynamical System (DEDS) theory can be utilized as a control strategy for future complex machine ensembles that will be required for in-space construction. The control strategy involves orchestrating a set of interactive submachines to perform a set of tasks for a given set of constraints such as minimum time, minimum energy, or maximum machine utilization. Machine ensembles can be hierarchically modeled as a global model that combines the operations of the individual submachines. These submachines are represented in the global model as local models. Local models, from the perspective of DEDS theory , are described by the following: a set of system and transition states, an event alphabet that portrays actions that takes a submachine from one state to another, an initial system state, a partial function that maps the current state and event alphabet to the next state, and the time required for the event to occur. Each submachine in the machine ensemble is presented by a unique local model. The global model combines the local models such that the local models can operate in parallel under the additional logistic and physical constraints due to submachine interactions. The global model is constructed from the states, events, event functions, and timing requirements of the local models. Supervisory control can be implemented in the global model by various methods such as task scheduling (open-loop control) or implementing a feedback DEDS controller (closed-loop control).

The Local Initiator Role in the Adoption of Biogas Energy Innovation for Household Needs in Rural Areas

Directory of Open Access Journals (Sweden)

Hartiningsih

2016-11-01

Full Text Available The need for Kerosene is very high. When energy crisis hit Indonesia, it caused the scarcity and soaring prices of kerosene. Hence, finding alternative energy sources is needed, especially a renewable energy to households. One is which is Biogas energy. Biogas is an energy that uses simple technology, which uses raw materials of animal waste. Many rural communities do not know about it, so it requires a pioneer, called the local initiator. The local initiator is an agent of change that comes from the local community, who has the initiative to make changes and become a guide passage of the change process in an organization or community, in order to achieve the expected goals. Local initiator becomes an important factor in the success of biogas innovation adoption. Biogas is used for household needs such as cooking, water heating, and lighting. Biogas program has been reinforced by Presidential Decree No 5 of 2006, Minister of ESDM Regulation (Permen ESDM No 3 of 2013, Permen ESDM No 10 of 2015, and Minister of Rural Affairs Regulation (Permen Desa No 5 of 2015. This paper aims to examine the role of a local initiator as an agent of change and the most dominant factors in the successful adoption of biogas for the needs of rural households. This study uses a qualitative method by using a case study approach and conducting a descriptive analysis. The focus of the data analysis is only performed on the local initiator in the successful adoption of biogas in Haurngombong village in West Java and Pandua-North Lombok, NTB. The result of the study shows that the successful adoption of biogas in Haurngombong Village and Pandua Village is strongly influenced by the local initiator. The local initiator success is not determined by the position, age, and gender, but is determined by the experience in the use of biogas, biogas sector knowledge, dissemination strategies, and communication among stakeholders of biogas program. The key to the success of local

Initialization and Restart in Stochastic Local Search: Computing a Most Probable Explanation in Bayesian Networks

Science.gov (United States)

Mengshoel, Ole J.; Wilkins, David C.; Roth, Dan

2010-01-01

For hard computational problems, stochastic local search has proven to be a competitive approach to finding optimal or approximately optimal problem solutions. Two key research questions for stochastic local search algorithms are: Which algorithms are effective for initialization? When should the search process be restarted? In the present work we investigate these research questions in the context of approximate computation of most probable explanations (MPEs) in Bayesian networks (BNs). We introduce a novel approach, based on the Viterbi algorithm, to explanation initialization in BNs. While the Viterbi algorithm works on sequences and trees, our approach works on BNs with arbitrary topologies. We also give a novel formalization of stochastic local search, with focus on initialization and restart, using probability theory and mixture models. Experimentally, we apply our methods to the problem of MPE computation, using a stochastic local search algorithm known as Stochastic Greedy Search. By carefully optimizing both initialization and restart, we reduce the MPE search time for application BNs by several orders of magnitude compared to using uniform at random initialization without restart. On several BNs from applications, the performance of Stochastic Greedy Search is competitive with clique tree clustering, a state-of-the-art exact algorithm used for MPE computation in BNs.

Initiating events identification of the IS process using the master logic diagram

International Nuclear Information System (INIS)

Cho, Nam Chul; Jae, Moo Sung; Yang, Joon Eon

2005-01-01

Hydrogen is very attractive as a future secondary energy carrier considering environmental problems. It is important to produce hydrogen from water by use of carbon free primary energy source. The thermochemical water decomposition cycle is one of the methods for the hydrogen production process from water. Japan Atomic Energy Research Institute (JAERI) has been carrying out an R and D on the IS (iodine.sulfur) process that was first proposed by GA (General Atomic Co.) focusing on demonstration the 'closed-cycle' continuous hydrogen production on developing a feasible and efficient scheme for the HI processing, and on screening and/or developing materials of construction to be used in the corrosive process environment. The successful continuous operation of the IS-process was demonstrated and this process is one of the thermochemical processes, which is the closest to being industrialized. Currently, Korea has also started a research about the IS process and the construction of the IS process system is planned. In this study, for risk analysis of the IS process, initiating events of the IS process are identified by using the Master Logic Diagram (MLD) that is method for initiating event identification

Moment magnitude determination of local seismic events recorded at selected Polish seismic stations

Science.gov (United States)

Wiejacz, Paweł; Wiszniowski, Jan

2006-03-01

The paper presents the method of local magnitude determination used at Polish seismic stations to report events originating in one of the four regions of induced seismicity in Poland or its immediate vicinity. The method is based on recalculation of the seismic moment into magnitude, whereas the seismic moment is obtained from spectral analysis. The method has been introduced at Polish seismic stations in the late 1990s but as of yet had not been described in full because magnitude discrepancies have been found between the results of the individual stations. The authors have performed statistics of these differences, provide their explanation and calculate station corrections for each station and each event source region. The limitations of the method are also discussed. The method is found to be a good and reliable method of local magnitude determination provided the limitations are observed and station correction applied.

A platform for local entrepreneurship

DEFF Research Database (Denmark)

Freire-Gibb, L. Carlos; Lorentzen, Anne

2011-01-01

This article discusses the birth and evolution of a festival that has targeted the entrepreneurial dynamics in the provincial city of Frederikshavn (North Denmark). The festival was initiated in 2004 to confront a local economic crisis and has enjoyed support from a broad range of stakeholders. I......-in. Empirically, the article is based on interviews with a wide range of actors across the organizing network. The article offers some preliminary lessons about what such an event can contribute to local entrepreneurship.......This article discusses the birth and evolution of a festival that has targeted the entrepreneurial dynamics in the provincial city of Frederikshavn (North Denmark). The festival was initiated in 2004 to confront a local economic crisis and has enjoyed support from a broad range of stakeholders...

Depth Discrimination Using Rg-to-Sg Spectral Amplitude Ratios for Seismic Events in Utah Recorded at Local Distances

Energy Technology Data Exchange (ETDEWEB)

Tibi, Rigobert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Koper, Keith D. [Univ. of Utah, Salt Lake City, UT (United States). Dept. of Geology and Geophysics; Pankow, Kristine L. [Univ. of Utah, Salt Lake City, UT (United States). Dept. of Geology and Geophysics; Young, Christopher J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2018-03-20

Short-period fundamental-mode Rayleigh waves (Rg) are commonly observed on seismograms of anthropogenic seismic events and shallow, naturally occurring tectonic earthquakes (TEs) recorded at local distances. In the Utah region, strong Rg waves traveling with an average group velocity of about 1.8 km/s are observed at ~1 Hz on waveforms from shallow events ( depth<10 km ) recorded at distances up to about 150 km. At these distances, Sg waves, which are direct shear waves traveling in the upper crust, are generally the dominant signals for TEs. Here in this study, we leverage the well-known notion that Rg amplitude decreases dramatically with increasing event depth to propose a new depth discriminant based on Rg-to-Sg spectral amplitude ratios. The approach is successfully used to discriminate shallow events (both earthquakes and anthropogenic events) from deeper TEs in the Utah region recorded at local distances ( <150 km ) by the University of Utah Seismographic Stations (UUSS) regional seismic network. Using Mood’s median test, we obtained probabilities of nearly zero that the median Rg-to-Sg spectral amplitude ratios are the same between shallow events on the one hand (including both shallow TEs and anthropogenic events), and deeper earthquakes on the other, suggesting that there is a statistically significant difference in the estimated Rg-to-Sg ratios between the two populations. We also observed consistent disparities between the different types of shallow events (e.g., mining blasts vs. mining-induced earthquakes), implying that it may be possible to separate the subpopulations that make up this group. Lastly, this suggests that using local distance Rg-to-Sg spectral amplitude ratios one can not only discriminate shallow events from deeper events but may also be able to discriminate among different populations of shallow events.

Impacts of extreme events of drought and flood on local communities of Amazon basin

Science.gov (United States)

Borma, L. D.; Roballo, S.; Zauner, M.; Nascimento, V. F.

2013-05-01

The analysis of drought events of 1997/98, 2005 and 2010 in terms of discharge anomalies in the Amazon region confirmed previous findings, such as: a) the influence of the El Niño in more than one hydrological year; b) the increase of the influence of the Atlantic Multidecadal Oscillation of 1998, 2005 and 2010 drought events; c) the low levels of discharge observed in the 2010 drought are attributed to the association of discharge anomalies of the northern and southern tributaries of the Amazon river, and d) the 2010 drought lasted around 1 month (August to November) more than the other drought events analized here. The riverine communities located along the river banks of Solimões/Amazonas suit their economic activities to the oscillation of the water level. In general, low water periods favor the access to important sources of food such as fish and livestock, still allowing crop cultivation on fertile agricultural areas of the floodplain. Conversely, periods of drought increases the difficulties of transport and drinking water supply. During the high water, access to the main food supply (described above) are greatly hampered. However, the floods are recognized as an importance process of natural fertilization. Thus, despite the political, social and economic shortcomings, the local community has, since the pre-colonial period, learned to get the best of each season, providing local, regional and national markets with varzea products. During periods of extreme weather, however, the advantages of each season appear to be reduced, and the drawbacks increased. In fact, during flooding extremes, the access to primary sources of food is hampered by a long period of time and families find themselves forced to leave their homes, eventually losing them. Analysis of flow data to the extreme flooding of 2009, indicate a period of about 6 months of positive anomalies discharge (occurring mainly during high water). At the same time, Civil Defense data points to a

76 FR 52263 - Special Local Regulation for Marine Events; Mattaponi Madness Drag Boat Race, Mattaponi River...

Science.gov (United States)

2011-08-22

... hour, make special local regulations necessary. However, the Coast Guard will provide advance... dangers posed by drag boat racing, operating in speeds excess of 150 miles per hour, make special local... side activities in the event area. The category of water activities includes but is not limited to sail...

A survey of local health promotion initiatives for older people in Wales

Directory of Open Access Journals (Sweden)

Williams Nefyn H

2008-06-01

Full Text Available Abstract Background As the demographic profile of the UK changes, policy makers and practitioners have to respond to health challenges presented by a progressively ageing population. The health promotion plan for older people, aged over 50 years, in Wales included eight key areas: physical activity, healthy eating, home safety and warmth, emotional health, health protection, smoking, alcohol and sexual health. The aim of this study was to describe the extent, content and regional variation of existing health promotion initiatives for older people in Wales, provided by statutory, voluntary and private sector agencies. Method A questionnaire was sent to senior health promotion specialists employed in the 22 local authority areas in Wales to ascertain details of all projects promoting health and wellbeing in the eight key areas where the priority population was aged over 50, or the majority of users were older people. Additional information was sought from project leads and websites. Results Eighteen questionnaires were returned; not all were fully completed. Four areas did not return a questionnaire. Additional information was obtained from internet searches but this mainly concerned national initiatives rather than local projects. In all, 120 projects were included, 11 were throughout Wales. Best provision was for physical activity, with 3 national and 42 local initiatives, but local provision was patchy. Healthy eating, and home safety and warmth had far fewer initiatives, as did health protection, which comprised two national immunisation campaigns. Smoking and alcohol misuse were poorly provided for, and there was no provision for older people's sexual health. Evaluation arrangements were poorly described. Half of those who responded identified unmet training needs. Conclusion The reasons for patchy provision of services were not clear. Increased efforts to improve the coverage of interventions known to be effective should be made. Rigorous

78 FR 72019 - Special Local Regulation; Southern California Annual Marine Events for the San Diego Captain of...

Science.gov (United States)

2013-12-02

... period via the Local Notice to Mariners and local advertising by the event sponsor. If the Captain of the... enforced for the full duration stated on this notice, he or she may use a Broadcast Notice to Mariners or...

Local seismicity in the area of Tornio River (northern Fennoscandia) revealed by analysis of local events registered by the POLENET/LAPNET array

Science.gov (United States)

Kozlovskaya, E.; Usoltseva, O.; Konstantinovskaya, N.

2012-04-01

The region of Tornio river (22-26 deg E and 66.5-69 deg N) is very interesting for seismological studies because it is crossed by systems of tectonic faults spreading in two different directions. 56 local earthquakes originated from this region were recorded by the POLENET/LAPNET temporary array from May, 2007 to May, 2009. Hypocenter depths of earthquakes are in the range of 1-35 km and their magnitudes vary from 0.8 to 2.2. For events detection we used the bulletin of the Institute of Seismology (Helsinki university) and Norway Global Beam Forming bulletin, compiled on the base of automatic detection of events, using the data of Noress, Arcess, Finess, SPA, HFS, APA arrays. In addition to local earthquakes, the array recorded 364 blasts from this region during the POLENET/LAPNET observation period. The events were relocated using manually measured travel times of refracted P waves from events at local distances (less than 200 km) and the 1-D velocity model along the wide-angle reflection and refraction HUKKA profile. The epicenters of relocated events show good correlation with known faults in the region. For each earthquake we constructed travel-time curves with reduction velocity of 8 km/s and compared them with the theoretical travel-time curves, in order to avoid phase misinterpretation. We found out that the largest reduction of travel time residuals during relocation was reached for deep earthquakes, due to more precise depth determination. The other aim of our study was to estimate what part of travel time residuals is not connected with the reference 1D velocity model and accuracy of location, but is rather due to 3-D heterogeneities in the crust. We also analyzed the amplitude characteristics of P-wave arrivals from different layers in the crust and upper mantle and also compared spectrograms of deep earthquakes, shallow earthquakes and blasts.

Event detection and localization for small mobile robots using reservoir computing.

Science.gov (United States)

Antonelo, E A; Schrauwen, B; Stroobandt, D

2008-08-01

Reservoir Computing (RC) techniques use a fixed (usually randomly created) recurrent neural network, or more generally any dynamic system, which operates at the edge of stability, where only a linear static readout output layer is trained by standard linear regression methods. In this work, RC is used for detecting complex events in autonomous robot navigation. This can be extended to robot localization tasks which are solely based on a few low-range, high-noise sensory data. The robot thus builds an implicit map of the environment (after learning) that is used for efficient localization by simply processing the input stream of distance sensors. These techniques are demonstrated in both a simple simulation environment and in the physically realistic Webots simulation of the commercially available e-puck robot, using several complex and even dynamic environments.

Local gamma ray events as tests of the antimatter theory of gamma ray bursts

International Nuclear Information System (INIS)

Sofia, S.; Wilson, R.E.

1976-01-01

Nearby examples of the antimatter 'chunks' postulated by Sofia and Van Horn to explain the cosmic gamma ray bursts may produce detectable gamma ray events when struck by solar system meteoroids. These events would have a much shorter time scale and higher energy spectrum than the bursts already observed. In order to have a reasonably high event rate, the local meteoroid population must extend to a distance from the Sun of the order of 0.1 pc, but the required distance could become much lower if the instrumental threshold is improved. The expected gamma ray flux for interaction of the antimatter bodies with the solar wind is also examined, and found to be far below present instrumental capabilities. (Auth.)

Fragile X founder chromosomes in Italy: A few initial events and possible explanation for their heterogeneity

Energy Technology Data Exchange (ETDEWEB)

Chiurazzi, P.; Genuardi, M.; Kozak, L.; Neri, G. [Universita Cattolica and Centro Ricerche per la Disabilita Mentale e Motoria, Roma (Italy)] [and others

1996-07-12

A total of 137 fragile X and 235 control chromosomes from various regions of Italy were haplotyped by analyzing two neighbouring marker microsatellites, FRAXAC1 and DXS548. The number of CGG repeats at the 5{prime} end of the FMR1 gene was also assessed in 141 control chromosomes and correlated with their haplotypes. Significant linkage disequilibrium between some {open_quotes}major{close_quotes} haplotypes and fragile X was observed, while other {open_quotes}minor{close_quotes} haplotypes may have originated by subsequent mutation at the marker microsatellite loci and/or recombination between them. Recent evidence suggests that the initial mechanism leading to CGG instability might consist of rare (10{sup -6/-7}) CGG repeat slippage events and/or loss of a stabilizing AGG via A-to-C transversion. Also, the apparently high variety of fragile X chromosomes may be partly due to the relatively high mutation rate (10{sup -4/-5}) of the microsatellite markers used in haplotyping. Our fragile X sample also showed a higher than expected heterozygosity when compared to the control sample and we suggest that this might be explained by the chance occurrence of the few founding events on different chromosomes, irrespective of their actual frequency in the population. Alternatively, a local mechanism could enhance the microsatellite mutation rate only on fragile X chromosomes, or fragile X mutations might occur more frequently on certain background haplotypes. 59 refs., 4 figs.

Event-based computer simulation model of aspect-type experiments strictly satisfying Einstein's locality conditions

NARCIS (Netherlands)

De Raedt, Hans; De Raedt, Koen; Michielsen, Kristel; Keimpema, Koenraad; Miyashita, Seiji

2007-01-01

Inspired by Einstein-Podolsky-Rosen-Bohtn experiments with photons, we construct an event-based simulation model in which every essential element in the ideal experiment has a counterpart. The model satisfies Einstein's criterion of local causality and does not rely on concepts of quantum and

Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice?

DEFF Research Database (Denmark)

NN, NN; Mugavero, Michael J; May, Margaret

2008-01-01

, nevirapine, lopinavir/ritonavir, nelfinavir, or abacavir as third drugs in combination with a zidovudine and lamivudine nucleoside reverse transcriptase inhibitor backbone. MAIN OUTCOME MEASURES: Short-term (24-week) virologic failure (>500 copies/ml) and clinical events within 2 years of ART initiation.......58-2.22), lopinavir/ritonavir (1.32, 95% CI = 1.12-1.57), nelfinavir (3.20, 95% CI = 2.74-3.74), and abacavir (2.13, 95% CI = 1.82-2.50). However, the rate of clinical events within 2 years of ART initiation appeared higher only with nevirapine (adjusted hazard ratio for composite outcome measure 1.27, 95% CI = 1......OBJECTIVE: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens translate to differences in clinical events in antiretroviral-naïve patients initiating ART. DESIGN: Observational cohort study of patients initiating ART between...

The relationship between transcription initiation RNAs and CCCTC-binding factor (CTCF localization

Directory of Open Access Journals (Sweden)

Taft Ryan J

2011-08-01

Full Text Available Abstract Background Transcription initiation RNAs (tiRNAs are nuclear localized 18 nucleotide RNAs derived from sequences immediately downstream of RNA polymerase II (RNAPII transcription start sites. Previous reports have shown that tiRNAs are intimately correlated with gene expression, RNA polymerase II binding and behaviors, and epigenetic marks associated with transcription initiation, but not elongation. Results In the present work, we show that tiRNAs are commonly found at genomic CCCTC-binding factor (CTCF binding sites in human and mouse, and that CTCF sites that colocalize with RNAPII are highly enriched for tiRNAs. To directly investigate the relationship between tiRNAs and CTCF we examined tiRNAs originating near the intronic CTCF binding site in the human tumor suppressor gene, p21 (cyclin-dependent kinase inhibitor 1A gene, also known as CDKN1A. Inhibition of CTCF-proximal tiRNAs resulted in increased CTCF localization and increased p21 expression, while overexpression of CTCF-proximal tiRNA mimics decreased CTCF localization and p21 expression. We also found that tiRNA-regulated CTCF binding influences the levels of trimethylated H3K27 at the alternate upstream p21 promoter, and affects the levels of alternate p21 (p21alt transcripts. Extending these studies to another randomly selected locus with conserved CTCF binding we found that depletion of tiRNA alters nucleosome density proximal to sites of tiRNA biogenesis. Conclusions Taken together, these data suggest that tiRNAs modulate local epigenetic structure, which in turn regulates CTCF localization.

Study of MHD events initiated by pellet injection into T-10 plasmas

International Nuclear Information System (INIS)

Kuteev, B.; Khimchenko, L.; Krylov, S.; Pavlov, Y.; Pustovitov, V.; Sarychev, D.; Sergeev, V.; Skokov, V.; Timokhin, V.

2005-01-01

There are several events which might be responsible for ultra fast transport of heat and particles during pellet ablation stage in a tokamak. Those are jumps of transport coefficients, plasma drifts in the pellet vicinity and MHD events with time scale significantly shorter than the pellet ablation time. The role of the latter is still not very well understood due to a lack of studies. This paper is devoted to detailed study of the effects during the pellet ablation phase (∼ one millisecond) with main objective to determine the relation between pellet (material Li, C., KCl, size and velocity) and plasma parameters ( q-value a the pellet position, plasma density and temperature) which initiate microsecond MHD events in plasma. The pellets were injected into both into Ohmic and ECE heated plasmas (up to 3 MW) in the T-10 tokamak at various stages of the plasma discharge, in a wide range from the very beginning up to the post-disruption stage. It is observed that at some conditions a pellet ablates in the plasma without accompanying MHD events. This occurs at the highest plasma densities even if a pellet penetrates through q=1 magnetic surface. The ablation rate corresponds to NGSM in this case. Small scale events may occur near rational magnetic surfaces and the ablation rate fluctuations may be explained by reconnection. Both increase of the longitudinal heat flow due to plasma conventional from higher temperature region and growth of the electric field generation supra-thermal electrons may be responsible for the enhanced ablation. Large scale MHD events envelop a region inside q<3. It is observed that the MHD-cooled area is not poloidally symmetric. Mechanisms of the phenomena observed and their consequences on tokamak operation are discussed. (Author)

75 FR 30296 - Special Local Regulation for Marine Event; Maryland Swim for Life, Chester River, Chestertown, MD

Science.gov (United States)

2010-06-01

... safety of life on navigable waters during the event. DATES: This rule is effective from 5:30 a.m. to 2:30...-AA08 Special Local Regulation for Marine Event; Maryland Swim for Life, Chester River, Chestertown, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is temporarily changing...

75 FR 47215 - Special Local Regulation; Marine Events Within the Captain of the Port Sector Boston Zone

Science.gov (United States)

2010-08-05

... special local regulations on: (1) The Charles River between the Longfellow Bridge and the Harvard Bridge... local regulations are established for the following marine events: (1) Charles River One Mile Swim, Charles River, Boston, MA. (i) Location. All waters of the Charles River, from surface to bottom, between...

Chimera states and the interplay between initial conditions and non-local coupling

Science.gov (United States)

Kalle, Peter; Sawicki, Jakub; Zakharova, Anna; Schöll, Eckehard

2017-03-01

Chimera states are complex spatio-temporal patterns that consist of coexisting domains of coherent and incoherent dynamics. We study chimera states in a network of non-locally coupled Stuart-Landau oscillators. We investigate the impact of initial conditions in combination with non-local coupling. Based on an analytical argument, we show how the coupling phase and the coupling strength are linked to the occurrence of chimera states, flipped profiles of the mean phase velocity, and the transition from a phase- to an amplitude-mediated chimera state.

Local Governments Supporting Local Energy Initiatives: Lessons from the Best Practices of Saerbeck (Germany and Lochem (The Netherlands

Directory of Open Access Journals (Sweden)

Thomas Hoppe

2015-02-01

Full Text Available The social dimension of the transition to a low carbon economy is a key challenge to cities. The establishment of local energy initiatives (LEIs has recently been attracting attention. It is of great importance to draw lessons from best practices when LEIs have been facilitated by local governments and made a substantial contribution to greening local energy systems. The main research questions in this paper are: What lessons can be drawn from successful local low carbon energy transition cases, and which strategies proved successful to support LEIs? We have used analytical notions from the Strategic Niche Management (SNM and grassroots innovation literature to analyze two best-practice cases: Saerbeck (Germany and Lochem (The Netherlands. Data collection involved a set of fourteen in-depth interviews and secondary data. The results show that three key factors from SNM (building networks, managing expectations, and facilitation of learning are of great importance. However, to a great degree it is also strategic, community serving, responsive, reflexive leadership and proper process management by public officials that spurred success, which would not have been possible without close interaction and mutual trust between local government and representatives of the local communities.

When the Sky Falls: Performing Initial Assessments of Bright Atmospheric Events

Science.gov (United States)

Cooke, William J.; Brown, Peter; Blaauw, Rhiannon; Kingery, Aaron; Moser, Danielle

2015-01-01

The 2013 Chelyabinsk super bolide was the first "significant" impact event to occur in the age of social media and 24 hour news. Scientists, used to taking many days or weeks to analyze fireball events, were hard pressed to meet the immediate demands (within hours) for answers from the media, general public, and government officials. Fulfilling these requests forced many researchers to exploit information available from various Internet sources - videos were downloaded from sites like Youtube, geolocated via Google Street View, and quickly analyzed with improvised software; Twitter and Facebook were scoured for eyewitness accounts of the fireball and reports of meteorites. These data, combined with infrasound analyses, enabled a fairly accurate description of the Chelyabinsk event to be formed within a few hours; in particular, any relationship to 2012 DA14 (which passed near Earth later that same day) was eliminated. Results of these analyses were quickly disseminated to members of the NEO community for press conferences and media interviews. Despite a few minor glitches, the rapid initial assessment of Chelyabinsk was a triumph, permitting the timely conveyance of accurate information to the public and the incorporation of social media into fireball analyses. Beginning in 2008, the NASA Meteoroid Environments Office, working in cooperation with Western's Meteor Physics Group, developed processes and software that permit quick characterization - mass, trajectory, and orbital properties - of fireball events. These tools include automated monitoring of Twitter to establish the time of events (the first tweet is usually no more than a few seconds after the fireball), mining of Youtube and all sky camera web archives to locate videos suitable for analyses, use of Google Earth and Street View to geolocate the video locations, and software to determine the fireball trajectory and object orbital parameters, including generation of animations suitable for popular media

Monitoring and forecasting local landslide hazard in the area of Longyearbyen, Svalbard - early progress and experiences from the Autumn 2016 events

Science.gov (United States)

Wang, Thea; Krøgli, Ingeborg; Boje, Søren; Colleuille, Hervé

2017-04-01

Since 2013 the Norwegian Water Resources and Energy Directorate (NVE) has operated a landslide early warning system (LEWS) for mainland Norway. The Svalbard islands, situated 800 km north of the Norwegian mainland, and 1200 km from the North Pole, are not part of the conventional early warning service. However, following the fatal snow avalanche event 19 Dec. 2015 in the settlement of Longyearbyen (78° north latitude), local authorities and the NVE have initiated monitoring of the hydro-meteorological conditions for the area of Longyearbyen, as an extraordinary precaution. Two operational forecasting teams from the NVE; the snow avalanche and the landslide hazard forecasters, perform hazard assessment related to snow avalanches, slush flows, debris flows, shallow slides and local flooding. This abstract will focus on recent experiences made by the landslide hazard team during the autumn 2016 landslide events, caused by a record setting wet and warm summer and autumn of 2016. The general concept of the Norwegian LEWS is based on frequency intervals of extreme hydro-meteorological conditions. This general concept has been transposed to the Longyearbyen area. Although the climate is considerably colder and drier than mainland Norway, experiences so far are positive and seem useful to the local authorities. Initially, the landslide hazard evaluation was intended to consider only slush flow hazard during the snow covered season. However, due to the extraordinary warm and wet summer and autumn 2016, the landslide hazard forecasters unexpectedly had to issue warnings for the local authorities due to increased risk of shallow landslides and debris flows. This was done in close cooperation with the Norwegian Meteorological Institute, who provided weather forecasts from the recently developed weather prediction model, AROME-Arctic. Two examples, from 14-15 Oct and 8-9 Nov 2016, will be given to demonstrate how the landslide hazard assessment for the Longyearbyen area is

Photodetection, photon event localization and position tomography device comprising a gammagraphy camera equipped wit such devices

International Nuclear Information System (INIS)

Jatteau, M.R.

1984-01-01

This device of photodetection and photon event (and noticeably scintillations) localization comprises at least a photomultiplier tube with unique photomultiplying structure and in front of this tube, a net of juxtaposed conduction metal wires excited by voltage pulses. This net comprises only 2n metallic wires to assure the localization of 2sup(2n) possible positions, and that is one of its characteristics [fr

New interaction paths in the energy landscape: the role of local energy initiatives

OpenAIRE

de Boer, Jessica; Zuidema, Christian; Gugerell, Katharina

2018-01-01

Energy transition is an encompassing process which not only involves the energy system but also the landscape in which the energy system is embedded. Renewable energy is triggering new interactions with local landscapes in physical, socio-economic and institutional senses. We capture these interactions using the energy landscape concept, which expresses the interdependence of the energy system with the landscape. We aim to understand whether and how local energy initiatives facilitate this in...

A geometric initial guess for localized electronic orbitals in modular biological systems

Energy Technology Data Exchange (ETDEWEB)

Beckman, P. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Univ. of Chicago, IL (United States); Fattebert, J. L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lau, E. Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Osei-Kuffuor, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-09-11

Recent first-principles molecular dynamics algorithms using localized electronic orbitals have achieved O(N) complexity and controlled accuracy in simulating systems with finite band gaps. However, accurately deter- mining the centers of these localized orbitals during simulation setup may require O(N³) operations, which is computationally infeasible for many biological systems. We present an O(N) approach for approximating orbital centers in proteins, DNA, and RNA which uses non-localized solutions for a set of fixed-size subproblems to create a set of geometric maps applicable to larger systems. This scalable approach, used as an initial guess in the O(N) first-principles molecular dynamics code MGmol, facilitates first-principles simulations in biological systems of sizes which were previously impossible.

Hypertension control after an initial cardiac event among Medicare patients with diabetes mellitus: A multidisciplinary group practice observational study.

Science.gov (United States)

Chaddha, Ashish; Smith, Maureen A; Palta, Mari; Johnson, Heather M

2018-04-23

Patients with diabetes mellitus and cardiovascular disease have a high risk of mortality and/or recurrent cardiovascular events. Hypertension control is critical for secondary prevention of cardiovascular events. The objective was to determine rates and predictors of achieving hypertension control among Medicare patients with diabetes and uncontrolled hypertension after hospital discharge for an initial cardiac event. A retrospective analysis of linked electronic health record and Medicare data was performed. The primary outcome was hypertension control within 1 year after hospital discharge for an initial cardiac event. Cox proportional hazard models assessed sociodemographics, medications, utilization, and comorbidities as predictors of control. Medicare patients with diabetes were more likely to achieve hypertension control when prescribed beta-blockers at discharge or with a history of more specialty visits. Adults ≥ 80 were more likely to achieve control with diuretics. These findings demonstrate the importance of implementing guideline-directed multidisciplinary care in this complex and high-risk population. ©2018 Wiley Periodicals, Inc.

Presentation of the results of a Bayesian automatic event detection and localization program to human analysts

Science.gov (United States)

Kushida, N.; Kebede, F.; Feitio, P.; Le Bras, R.

2016-12-01

The Preparatory Commission for the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) has been developing and testing NET-VISA (Arora et al., 2013), a Bayesian automatic event detection and localization program, and evaluating its performance in a realistic operational mode. In our preliminary testing at the CTBTO, NET-VISA shows better performance than its currently operating automatic localization program. However, given CTBTO's role and its international context, a new technology should be introduced cautiously when it replaces a key piece of the automatic processing. We integrated the results of NET-VISA into the Analyst Review Station, extensively used by the analysts so that they can check the accuracy and robustness of the Bayesian approach. We expect the workload of the analysts to be reduced because of the better performance of NET-VISA in finding missed events and getting a more complete set of stations than the current system which has been operating for nearly twenty years. The results of a series of tests indicate that the expectations born from the automatic tests, which show an overall overlap improvement of 11%, meaning that the missed events rate is cut by 42%, hold for the integrated interactive module as well. New events are found by analysts, which qualify for the CTBTO Reviewed Event Bulletin, beyond the ones analyzed through the standard procedures. Arora, N., Russell, S., and Sudderth, E., NET-VISA: Network Processing Vertically Integrated Seismic Analysis, 2013, Bull. Seismol. Soc. Am., 103, 709-729.

Ohio’s Research Initiative for Locals Peer Exchange Report, March 8-9, 2017

Science.gov (United States)

2017-10-23

On March 8-9, 2017, the Ohio Department of Transportation (ODOT) hosted a peer exchange on behalf of the Ohios Research Initiative for Locals (ORIL) program. Peer exchanges provide an opportunity to foster best practices and evaluate processes wit...

Defining molecular initiating events in the adverse outcome pathway framework for risk assessment.

Science.gov (United States)

Allen, Timothy E H; Goodman, Jonathan M; Gutsell, Steve; Russell, Paul J

2014-12-15

Consumer and environmental safety decisions are based on exposure and hazard data, interpreted using risk assessment approaches. The adverse outcome pathway (AOP) conceptual framework has been presented as a logical sequence of events or processes within biological systems which can be used to understand adverse effects and refine current risk assessment practices in ecotoxicology. This framework can also be applied to human toxicology and is explored on the basis of investigating the molecular initiating events (MIEs) of compounds. The precise definition of the MIE has yet to reach general acceptance. In this work we present a unified MIE definition: an MIE is the initial interaction between a molecule and a biomolecule or biosystem that can be causally linked to an outcome via a pathway. Case studies are presented, and issues with current definitions are addressed. With the development of a unified MIE definition, the field can look toward defining, classifying, and characterizing more MIEs and using knowledge of the chemistry of these processes to aid AOP research and toxicity risk assessment. We also present the role of MIE research in the development of in vitro and in silico toxicology and suggest how, by using a combination of biological and chemical approaches, MIEs can be identified and characterized despite a lack of detailed reports, even for some of the most studied molecules in toxicology.

The development on the methodology of the initiating event frequencies for liquid metal reactor KALIMER

International Nuclear Information System (INIS)

Jeong, K. S.; Yang, Z. A.; Ah, Y. B.; Jang, W. P.; Jeong, H. Y.; Ha, K. S.; Han, D. H.

2002-01-01

In this paper, the PSA methodology of PRISM,Light Water Reactor, Pressurized Heavy Water Reactor are analyzed and the methodology of Initiating Events for KALIMER are suggested. Also,the reliability assessment of assumptions for Pipes Corrosion Frequency is set up. The reliability assessment of Passive Safety System, one of Main Safety System of KALIMER, are discussed and analyzed

A Performance Management Initiative for Local Health Department Vector Control Programs.

Science.gov (United States)

Gerding, Justin; Kirshy, Micaela; Moran, John W; Bialek, Ron; Lamers, Vanessa; Sarisky, John

2016-01-01

Local health department (LHD) vector control programs have experienced reductions in funding and capacity. Acknowledging this situation and its potential effect on the ability to respond to vector-borne diseases, the U.S. Centers for Disease Control and Prevention and the Public Health Foundation partnered on a performance management initiative for LHD vector control programs. The initiative involved 14 programs that conducted a performance assessment using the Environmental Public Health Performance Standards. The programs, assisted by quality improvement (QI) experts, used the assessment results to prioritize improvement areas that were addressed with QI projects intended to increase effectiveness and efficiency in the delivery of services such as responding to mosquito complaints and educating the public about vector-borne disease prevention. This article describes the initiative as a process LHD vector control programs may adapt to meet their performance management needs. This study also reviews aggregate performance assessment results and QI projects, which may reveal common aspects of LHD vector control program performance and priority improvement areas. LHD vector control programs interested in performance assessment and improvement may benefit from engaging in an approach similar to this performance management initiative.

Large developing receptive fields using a distributed and locally reprogrammable address-event receiver.

Science.gov (United States)

Bamford, Simeon A; Murray, Alan F; Willshaw, David J

2010-02-01

A distributed and locally reprogrammable address-event receiver has been designed, in which incoming address-events are monitored simultaneously by all synapses, allowing for arbitrarily large axonal fan-out without reducing channel capacity. Synapses can change the address of their presynaptic neuron, allowing the distributed implementation of a biologically realistic learning rule, with both synapse formation and elimination (synaptic rewiring). Probabilistic synapse formation leads to topographic map development, made possible by a cross-chip current-mode calculation of Euclidean distance. As well as synaptic plasticity in rewiring, synapses change weights using a competitive Hebbian learning rule (spike-timing-dependent plasticity). The weight plasticity allows receptive fields to be modified based on spatio-temporal correlations in the inputs, and the rewiring plasticity allows these modifications to become embedded in the network topology.

Risk assessment of K basin twelve-inch drain valve failure from a postulated seismic initiating event

International Nuclear Information System (INIS)

MORGAN, R.G.

1999-01-01

The Spent Nuclear Fuel (SNF) Project will transfer metallic SNF from the Hanford 105 K-East and 105 K-West Basins to safe interim storage in the Canister Storage Building in the 200 Area. The initial basis for design, fabrication, installation, and operation of the fuel removal systems was that the basin leak rates which could result from a postulated accident condition would not be excessive relative to reasonable recovery operations. However, an additional potential K Basin water leak path is through the K Basin drain valves. Three twelve-inch drain valves are located in the main basin bays along the north wall. The sumps containing the valves are filled with concrete which covers the drain valve body. Visual observations suggest that only the valve's bonnet and stem are exposed above the basin concrete floor. It was recognized, however, that damage of the drain valve bonnet or stem during a seismic initiating event could provide a potential K Basin water leak path. The objectives of this activity are to: (1) evaluate the risk of damaging the three twelve-inch drain valves located along the north wall of the main basin from a seismic initiating event, and (2) determine the associated potential leak rate from a damaged valve

Risk assessment of K basin twelve-inch drain valve failure from a postulated seismic initiating event

Energy Technology Data Exchange (ETDEWEB)

MORGAN, R.G.

1999-04-06

The Spent Nuclear Fuel (SNF) Project will transfer metallic SNF from the Hanford 105 K-East and 105 K-West Basins to safe interim storage in the Canister Storage Building in the 200 Area. The initial basis for design, fabrication, installation, and operation of the fuel removal systems was that the basin leak rates which could result from a postulated accident condition would not be excessive relative to reasonable recovery operations. However, an additional potential K Basin water leak path is through the K Basin drain valves. Three twelve-inch drain valves are located in the main basin bays along the north wall. The sumps containing the valves are filled with concrete which covers the drain valve body. Visual observations suggest that only the valve's bonnet and stem are exposed above the basin concrete floor. It was recognized, however, that damage of the drain valve bonnet or stem during a seismic initiating event could provide a potential K Basin water leak path. The objectives of this activity are to: (1) evaluate the risk of damaging the three twelve-inch drain valves located along the north wall of the main basin from a seismic initiating event, and (2) determine the associated potential leak rate from a damaged valve.

Is local equilibrium a useful concept in hadronic interactions

International Nuclear Information System (INIS)

Carruthers, P.

1984-01-01

Aspects of multiparticle production phenomena are reviewed, which bear on the existence of local equilibrium in all or part of a collision event. Several universal features of purely hadronic events, such as the p/sub perpendicular/ distribution of secondaries, the independence of multiplicities and multiplicity distributions on the quantum numbers of the colliding particles are easily interpreted by postulating the existence of local thermodynamic equilibrium for the dominant nondiffractive events. Except in the case of the multiplicity distribution, other interpretations often do not exist. Equilibration mechanisms which might establish local equilibrium are examined. We point out that several mechanisms besides the usual kinetic relaxation have not been seriously studied. These include collective instabilities, turbulence and chaos, which could be more effective in establishing equilibrium. Developments in the use of the hydrodynamic model are reviewed, with particular attention to the initial conditions appropriate to hadronic and nuclear collisions. We conclude that local equilibrium is indeed a useful concept but that much effort is needed to assess its accuracy and domain of applicability

Blast experiments for the derivation of initial cloud dimensions after a ''Dirty Bomb'' event

International Nuclear Information System (INIS)

Thielen, H.; Schroedl, E.

2004-01-01

Basis for the assessment of potential consequences of a ''dirty bomb'' event is the calculation of the atmospheric dispersion of airborne particles. The empirical derivation of parameters for the estimation of the initial pollutant cloud dimensions was the principal purpose for blast experiments performed in the training area Munster in summer 2003 with the participation of several highly engaged German organisations and institutions. The experiments were performed under variation of parameters like mass and kind of explosive, subsurface characteristics or meteorological conditions and were documented by digital video recording. The blasting experiments supplied significant results under reproducible conditions. The initial cloud dimension was primarily influenced by the explosive mass. The influence of other parameters was relatively small and within the range of the experimental uncertainties. Based on these experimental results a new correlation was determined for the empirical estimation of the initial cloud dimensions as a function of explosive mass. The observed initial cloud volumes were more than an order of magnitude smaller than those calculated with other widely-used formulas (e.g. HOTSPOT). As a smaller volume of the initial cloud leads to higher near-ground concentration maxima, our results support an appropriate adjustment of currently employed calculation methods. (orig.)

Initial concepts on energetics and mass releases during nonnuclear explosive events in fuel cycle facilities

International Nuclear Information System (INIS)

Halverson, M.A.; Mishima, J.

1986-09-01

Non-nuclear explosions are one of the initiating events (accidents) considered in the US Nuclear Regulatory Commission study of formal methods for estimating the airborne release of radionuclides from fuel cycle facilities. Methods currently available to estimate the energetics and mass airborne release from the four types of non-nuclear explosive events (fast and slow physical explosions and fast and slow chemical explosions) are reviewed. The likelihood that fast physical explosions will occur in fuel cycle facilities appears to be remote and this type of explosion is not considered. Methods to estimate the consequences of slow physical and fast chemical explosions are available. Methods to estimate the consequences of slow chemical explosions are less well defined

Energy and greenhouse gas inventories by local governments in BC : implications for the CEEI initiative

International Nuclear Information System (INIS)

Macdonald, R.

2007-01-01

The community energy and emissions inventory (CEEI) initiative has been undertaken through British Columbia's Ministry of Environment in order to establish a cost-effective, provincially-sponsored, rigorous, yet flexible, data collection, analysis and reporting system to provide local governments with energy-related and greenhouse gas inventory baselines, ongoing monitoring and periodic reports to help inform community decision making and support provincial objectives. This report described the CEEI initiative including background information, project objectives, and project methodology. The report also provided a review of community and corporate inventories and discussed the implications of various data and methodological issues for the CEEI initiative. This included reporting and updating issues; desired accuracy and frequency of community inventories; regular inventory generation; and implications for the development of indicators. The report concluded with a sampling of possible indicators, and the factors that affect their use. It was concluded that the characteristics of an ideal indicator for local action on climate change would be one that describes a condition or state of the urban or built environment representing the magnitude of emissions. It would also be one that is within the influence of local governments to affect and would be both measurable and affordable. 11 tabs., 2 appendices

Study of local seismic events in Lithuania and adjacent areas using data from the PASSEQ experiment

Czech Academy of Sciences Publication Activity Database

Janutyte, I.; Kozlovskaya, E.; Motuza, G.; Plomerová, Jaroslava; Babuška, Vladislav; Gaždová, Renata; Jedlička, Petr; Kolínský, Petr; Málek, Jiří; Novotný, Oldřich; Růžek, Bohuslav

2013-01-01

Roč. 170, č. 5 (2013), s. 797-814 ISSN 0033-4553 Institutional support: RVO:67985530 ; RVO:67985891 Keywords : location of local seismic events * East European Craton * PASSEQ passive seismic experiment Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.854, year: 2013

Accident analyses in nuclear power plants following external initiating events and in the shutdown state. Final report

International Nuclear Information System (INIS)

Loeffler, Horst; Kowalik, Michael; Mildenberger, Oliver; Hage, Michael

2016-06-01

The work which is documented here provides the methodological basis for improvement of the state of knowledge for accident sequences after plant external initiating events and for accident sequences which begin in the shutdown state. The analyses have been done for a PWR and for a BWR reference plant. The work has been supported by the German federal ministry BMUB under the label 3612R01361. Top objectives of the work are: - Identify relevant event sequences in order to define characteristic initial and boundary conditions - Perform accident analysis of selected sequences - Evaluate the relevance of accident sequences in a qualitative way The accident analysis is performed with the code MELCOR 1.8.6. The applied input data set has been significantly improved compared to previous analyses. The event tree method which is established in PSA level 2 has been applied for creating a structure for a unified summarization and evaluation of the results from the accident analyses. The computer code EVNTRE has been applied for this purpose. In contrast to a PSA level 2, the branching probabilities of the event tree have not been determined with the usual accuracy, but they are given in an approximate way only. For the PWR, the analyses show a considerable protective effect of the containment also in the case of beyond design events. For the BWR, there is a rather high probability for containment failure under core melt impact, but nevertheless the release of radionuclides into the environment is very limited because of plant internal retention mechanisms. This report concludes with remarks about existing knowledge gaps and with regard to core melt sequences, and about possible improvements of the plant safety.

Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice?

NARCIS (Netherlands)

Mugavero, Michael J; May, Margaret; Harris, Ross; Saag, Michael S; Costagliola, Dominique; Egger, Matthias; Phillips, Andrew; Günthard, Huldrych F; Dabis, Francois; Hogg, Robert; de Wolf, Frank; Fatkenheuer, Gerd; Gill, M John; Justice, Amy; D'Arminio Monforte, Antonella; Lampe, Fiona; Miró, Jose M; Staszewski, Schlomo; Sterne, Jonathan A C; Niesters, Bert

2008-01-01

OBJECTIVE: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens translate to differences in clinical events in antiretroviral-naïve patients initiating ART. DESIGN: Observational cohort study of patients initiating ART between

LOCAL INITIATIVES FOR SUSTAINABLE DEVELOPMENT IN RURAL HOKKAIDO: A CASE STUDY OF SAMANI

Directory of Open Access Journals (Sweden)

Devon Dublin

2013-01-01

Full Text Available The paper presents the results of a field investigation about sustainable development of Samani town—a rural area in Hidaka region, Hokkaido, Japan. Local activities, business, environmental, social and economic challenges that affect the town as well as the advantages were investigated. The research was done by means of field visits, questionnaires and interviews involving the local people and government. The main economic sectors: olivine industry, fishery, agriculture and tourism were targeted as well as the government sector and the local high school with a particular focus on rural-urban migration. Samani has quite unique natural features on hand but a few strong comprehensive challenges on the other hand. The authors focused on the citizens opinions and positions which were based on the uniqueness of Samani and their own local activities and initiatives for the sustainable development of the town in the future which can be replicated in other rural communities around the world.

Attending to global versus local stimulus features modulates neural processing of low versus high spatial frequencies: An analysis with event-related brain potentials.

Directory of Open Access Journals (Sweden)

Anastasia V Flevaris

2014-04-01

Full Text Available Spatial frequency (SF selection has long been recognized to play a role in global and local processing, though the nature of the relationship between SF processing and global/local perception is debated. Previous studies have shown that attention to relatively lower SFs facilitates global perception, and that attention to relatively higher SFs facilitates local perception. Here we recorded event-related brain potentials (ERPs to investigate whether processing of low versus high SFs is modulated automatically during global and local perception, and to examine the time course of any such effects. Participants compared bilaterally presented hierarchical letter stimuli and attended to either the global or local levels. Irrelevant SF grating probes flashed at the center of the display 200 ms after the onset of the hierarchical letter stimuli could either be low or high in SF. It was found that ERPs elicited by the SF grating probes differed as a function of attended level (global vs. local. ERPs elicited by low SF grating probes were more positive in the interval 196-236 ms during global than local attention, and this difference was greater over the right occipital scalp. In contrast, ERPs elicited by the high SF gratings were more positive in the interval 250-290 ms during local than global attention, and this difference was bilaterally distributed over the occipital scalp. These results indicate that directing attention to global versus local levels of a hierarchical display facilitates automatic perceptual processing of low versus high SFs, respectively, and this facilitation is not limited to the locations occupied by the hierarchical display. The relatively long latency of these attention-related ERP modulations suggests that initial (early SF processing is not affected by attention to hierarchical level, lending support to theories positing a higher level mechanism to underlie the relationship between SF processing and global versus local

44. Causes of initiation and promotion of cannabis among local transport drivers of Peshawar

Directory of Open Access Journals (Sweden)

Hamzullah Khan

2015-10-01

Conclusion: Cannabis smoking is common in local transport drivers. The major causes that are involved in the initiation and progression of cannabis smoking are; driving in young age, poverty, lack of education, easy availability of cannabis, inspiration from colleagues and smoker parents.

Earthquake precursory events around epicenters and local active faults

Science.gov (United States)

Valizadeh Alvan, H.; Mansor, S. B.; Haydari Azad, F.

2013-05-01

shakes, mapping foreshocks and aftershocks, and following changes in the above-mentioned precursors prior to past earthquake instances all over the globe. Our analyses also encompass the geographical location and extents of local and regional faults which are considered as important factors during earthquakes. The co-analysis of direct and indirect observation for precursory events is considered as a promising method for possible future successful earthquake predictions. With proper and thorough knowledge about the geological setting, atmospheric factors and geodynamics of the earthquake-prone regions we will be able to identify anomalies due to seismic activity in the earth's crust.

78 FR 13576 - Special Local Regulations and Safety Zones; Recurring Marine Events and Fireworks Displays Within...

Science.gov (United States)

2013-02-28

..., local, or tribal government, in the aggregate, or by the private sector of $100,000,000 (adjusted for... administrative workload and expedite public notification of events. Entry into or movement within these proposed... detailed description of the geographical area of the district and each Coast Guard Sector--Captain of the...

‘Initiative-Decision’ Typology of New Product Launching (NPL into Local Market: Toward Interaction Mechanism

Directory of Open Access Journals (Sweden)

Firmanzah

2009-12-01

Full Text Available New product launching (NPL process in subsidiaries is very complex, expensive and risky. This process is marked by the problem of role partition between headquarter and subsidiaries. This research emphasizes the quality of relation between subsidiaries and headquarter which determines the qualities of NPL process into local market. Typology of initiative-decision during NPL process has been documented. Using cluster analysis, three clusters of ‘initiative-decision’ during NPL are found in this research: ‘headquarters domination’, ‘mix-initiative’ and ‘interaction’. Using ANOVA analysis, this research found that interaction between subsidiary and headquarter managers positively increases the effectiveness of marketing-strategy during NPL process. This finding suggests that interaction mechanism between subsidiary and headquarter is the best solution to launch a new product to the local market.

75 FR 41373 - Special Local Regulations for Marine Events; Port Huron to Mackinac Island Sail Race

Science.gov (United States)

2010-07-16

...-AA08 Special Local Regulations for Marine Events; Port Huron to Mackinac Island Sail Race AGENCY: Coast... regulation for the annual Port Huron to Mackinac Island Sail Race. This action is necessary to safely control... the Port Sector Detroit has determined that the start of the Port Huron to Mackinac Island Sail Race...

Hydrometeorological threshold conditions for debris flow initiation in Norway

Directory of Open Access Journals (Sweden)

N. K. Meyer

2012-10-01

Full Text Available Debris flows, triggered by extreme precipitation events and rapid snow melt, cause considerable damage to the Norwegian infrastructure every year. To define intensity-duration (ID thresholds for debris flow initiation critical water supply conditions arising from intensive rainfall or snow melt were assessed on the basis of daily hydro-meteorological information for 502 documented debris flow events. Two threshold types were computed: one based on absolute ID relationships and one using ID relationships normalized by the local precipitation day normal (PDN. For each threshold type, minimum, medium and maximum threshold values were defined by fitting power law curves along the 10th, 50th and 90th percentiles of the data population. Depending on the duration of the event, the absolute threshold intensities needed for debris flow initiation vary between 15 and 107 mm day⁻¹. Since the PDN changes locally, the normalized thresholds show spatial variations. Depending on location, duration and threshold level, the normalized threshold intensities vary between 6 and 250 mm day⁻¹. The thresholds obtained were used for a frequency analysis of over-threshold events giving an estimation of the exceedance probability and thus potential for debris flow events in different parts of Norway. The absolute thresholds are most often exceeded along the west coast, while the normalized thresholds are most frequently exceeded on the west-facing slopes of the Norwegian mountain ranges. The minimum thresholds derived in this study are in the range of other thresholds obtained for regions with a climate comparable to Norway. Statistics reveal that the normalized threshold is more reliable than the absolute threshold as the former shows no spatial clustering of debris flows related to water supply events captured by the threshold.

Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment

DEFF Research Database (Denmark)

Rasmussen, Hanne B; Frøkjaer-Jensen, Christian; Jensen, Camilla Stampe

2007-01-01

The potassium channel subunits KCNQ2 and KCNQ3 are believed to underlie the M current of hippocampal neurons. The M-type potassium current plays a key role in the regulation of neuronal excitability; however, the subcellular location of the ion channels underlying this regulation has been...... controversial. We report here that KCNQ2 and KCNQ3 subunits are localized to the axon initial segment of pyramidal neurons of adult rat hippocampus and in cultured hippocampal neurons. We demonstrate that the localization of the KCNQ2/3 channel complex to the axon initial segment is favored by co...

Safety consequences of local initiating events in an LMFBR

Energy Technology Data Exchange (ETDEWEB)

Crawford, R.M.; Marr, W.W.; Padilla, A. Jr.; Wang, P.Y.

1975-12-01

The potential for fuel-failure propagation in an LMFBR at or near normal conditions is examined. Results are presented to support the conclusion that although individual fuel-pin failure may occur, rapid failure-propagation spreading among a large number of fuel pins in a subassembly is unlikely in an operating LMFBR. This conclusion is supported by operating experience, mechanistic analyses of failure-propagation phenomena, and experiments. In addition, some of the consequences of continued operation with defected fuel are considered.

Safety consequences of local initiating events in an LMFBR

International Nuclear Information System (INIS)

Crawford, R.M.; Marr, W.W.; Padilla, A. Jr.; Wang, P.Y.

1975-12-01

The potential for fuel-failure propagation in an LMFBR at or near normal conditions is examined. Results are presented to support the conclusion that although individual fuel-pin failure may occur, rapid failure-propagation spreading among a large number of fuel pins in a subassembly is unlikely in an operating LMFBR. This conclusion is supported by operating experience, mechanistic analyses of failure-propagation phenomena, and experiments. In addition, some of the consequences of continued operation with defected fuel are considered

Restoring the capacity for initiative to local authorities for the development of ENR

International Nuclear Information System (INIS)

Gouvello, Ch. de; Nadaud, F.

2001-01-01

The decree of June 8. 2001 concerning wind powered electricity purchase prices as a sign of public support in terms of industrial policy. The recent debates have given the local authorities a key role in the development of ENR systems although concrete achievements so far remain quite limited We will demonstrate that this is essentially explained by the fact that the skills of local authorities chiefly lie in the discrete framework of the Rural Electrification scheme. Based on examples of thermal ENR systems in housing and of electrical production via ENR systems connected to the network, we will show that the Rural Electrification scheme has the effect of focusing the technical choices of local authorities on the traditional technology of the distribution networks. A minor modification to the Rural Electrification scheme would make it possible to give the capacity for initiative back to local authorities with regard to ENR systems, while at the same time making it possible to contribute to resolving the question of the reinforcement of transportation and distribution networks in order to incorporate production obtained from ENR systems. (authors)

78 FR 54571 - Special Local Regulation for Marine Event Hampton Bay Days Festival, Hampton River; Hampton, VA

Science.gov (United States)

2013-09-05

...-AA08 Special Local Regulation for Marine Event Hampton Bay Days Festival, Hampton River; Hampton, VA... Fifth Coast Guard District. This regulation applies only to the Hampton Bay Days Festival, which... Purpose Hampton Bay Days is sponsoring the three days Hampton Bay Days Festival, which includes a...

Local energy ownership in Europe. An exploratory study of local public initiatives in France, Germany and the United Kingdom

International Nuclear Information System (INIS)

Ruedinger, Andreas

2017-06-01

Across Europe, a growing number of local authorities are eager to regain control over energy systems on a wide range of scales and modalities. Through an exploratory study authored by Andreas Ruedinger and funded by the French Agency for Energy Management (ADEME), Energy Cities decided to shed light on the various nuances surrounding this phenomenon of local reclaim over energy systems and offer new perspectives to cities wishing to replicate successful initiatives. This European overview focuses mainly on three countries: Germany, which could almost be described as the cradle of re-municipalization, the United Kingdom and France. Local energy management can take many forms, and the study outlines and develops four specific processes: 1. re-municipalization, 2. Political decentralization, 3. Citizen projects, 4. Participatory governance. More and more cities are taking a leading role in driving the energy transition, not only as planning authorities but also as an operational actors, inspired in particular by examples of re-municipalization in the water sector. Whether it is through the creation of new integrated municipal companies such as Germany, public energy suppliers such as the UK, or local operators investing in renewable energy and energy efficiency projects. France, we see the outlines of a movement of re-appropriation of energy transition by local communities, the study finds. The reasons and opportunities that motivate local authorities to embark on re-municipalization projects are multiple: revitalizing the local economy, creating a close connection with citizens, managing local public services in a more integrated way, fostering cooperation and partnerships with other players, accessing new markets, etc. However, as the study points out, these endeavors can also come with some risks, such as the competitive pressure exerted by the private sector and the limited influence over national and European energy policies

Local energy ownership in Europe. An exploratory study of local public initiatives in France, Germany and the United Kingdom

International Nuclear Information System (INIS)

Ruedinger, Andreas

2017-06-01

Across Europe, a growing number of local authorities are eager to regain control over energy systems on a wide range of scales and modalities. Through an exploratory study authored by Andreas Ruedinger and funded by the French Agency for Energy Management (ADEME), Energy Cities decided to shed light on the various nuances surrounding this phenomenon of local reclaim over energy systems and offer new perspectives to cities wishing to replicate successful initiatives. This European overview focuses mainly on three countries: Germany, which could almost be described as the cradle of re-municipalization, the United Kingdom and France. Local energy management can take many forms, and the study outlines and develops four specific processes: 1. Re-municipalization, 2. Political decentralization, 3. Citizen projects, 4. Participatory governance. More and more cities are taking a leading role in driving the energy transition, not only as planning authorities but also as an operational actors, inspired in particular by examples of re-municipalization in the water sector. Whether it is through the creation of new integrated municipal companies such as Germany, public energy suppliers such as the UK, or local operators investing in renewable energy and energy efficiency projects. France, we see the outlines of a movement of re-appropriation of energy transition by local communities, the study finds. The reasons and opportunities that motivate local authorities to embark on re-municipalization projects are multiple: revitalizing the local economy, creating a close connection with citizens, managing local public services in a more integrated way, fostering cooperation and partnerships with other players, accessing new markets, etc. However, as the study points out, these endeavors can also come with some risks, such as the competitive pressure exerted by the private sector and the limited influence over national and European energy policies

Radiotherapy for locally recurrent rectal cancer treated with surgery alone as the initial treatment

Energy Technology Data Exchange (ETDEWEB)

Tanaka, Hidekazu; Yamaguchi, Takahiro; Hachiya, Kae; Okada, Sunaho; Kitahara, Masashi; Matsuyama, Katsuya; Matsuo, Masayuki [Gifu University, Gifu (Japan)

2017-03-15

Although the technical developments of radiotherapy have been remarkable, there are currently few reports on the treatment results of radiotherapy for local recurrence of rectal cancer treated with surgery alone as initial treatment in this three-dimensional conformal radiotherapy era. Thus, we retrospectively evaluated the treatment results of radiotherapy for local recurrence of rectal cancer treated with surgery alone as the initial treatment. Thirty-two patients who underwent radiotherapy were enrolled in this study. The dose per fraction was 2.0–3.5 Gy. Because the treatment schedule was variable, the biological effective dose (BED) was calculated. Local control (LC) and overall survival (OS) rates from the completion of radiotherapy were calculated. The 1-, 2-, 3-, 4-, and 5-year LC rates were 51.5%, 24.5%, 19.6%, 19.6%, and 13.1%, respectively. LC rates were significantly higher for the high BED group (≥75 Gy10) than for the lower BED group (<75 Gy10). All patients who reported pain achieved pain relief. The duration of pain relief was significantly higher for the high BED group than for the lower BED group. The 1-, 2-, 3-, 4-, and 5-year OS rates were 82.6%, 56.5%, 45.2%, 38.7%, and 23.2%, respectively. There was a trend toward higher OS rates in with higher BED group compared to lower BED group. For patients with unresectable locally recurrent rectal cancer treated with surgery alone, radiotherapy is effective treatment. The prescribed BED should be more than 75 Gy10, if the dose to the organ at risk is within acceptable levels.

Determination of the Support Level of Local Organizations in a Model Forest Initiative: Do Local Stakeholders Have Willingness to Be Involved in the Model Forest Development?

Directory of Open Access Journals (Sweden)

Ahmet Tolunay

2014-10-01

Full Text Available Voluntary cooperation and the support of stakeholders carry a major importance in the development of Model Forests. The identification of the support level of local organizations as stakeholders in the Bucak Model Forest initiative, located in the Mediterranean region of Turkey, constitutes the theme of this study. Within this scope, the views of the stakeholders comprising local government units (LGUs, non-governmental organizations (NGOs, village councils (VCs, professional organizations (POs and forest products enterprises (FPEs located in the district of Bucak were collected by utilizing a survey technique. The data were analysed by using non-parametric statistical analyses due to the absence of a normal distribution. The results show that the information provided about the Model Forest concept to the stakeholders located in the district on the Bucak Model Forest initiative was identified as a factor impacting the support level. Moreover, it was also observed that the stakeholders were more willing to provide advisory support rather than financial support. NGOs and VCs were identified as stakeholders who could not provide financial support due to their restricted budgets. We discuss the benefits for a Model Forest initiative of establishing international cooperation to strengthen the local and regional sustainable development process.

Constraints on rapidity-dependent initial conditions from charged-particle pseudorapidity densities and two-particle correlations

Science.gov (United States)

Ke, Weiyao; Moreland, J. Scott; Bernhard, Jonah E.; Bass, Steffen A.

2017-10-01

We study the initial three-dimensional spatial configuration of the quark-gluon plasma (QGP) produced in relativistic heavy-ion collisions using centrality and pseudorapidity-dependent measurements of the medium's charged particle density and two-particle correlations. A cumulant-generating function is first used to parametrize the rapidity dependence of local entropy deposition and extend arbitrary boost-invariant initial conditions to nonzero beam rapidities. The model is then compared to p +Pb and Pb + Pb charged-particle pseudorapidity densities and two-particle pseudorapidity correlations and systematically optimized using Bayesian parameter estimation to extract high-probability initial condition parameters. The optimized initial conditions are then compared to a number of experimental observables including the pseudorapidity-dependent anisotropic flows, event-plane decorrelations, and flow correlations. We find that the form of the initial local longitudinal entropy profile is well constrained by these experimental measurements.

Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack

Energy Technology Data Exchange (ETDEWEB)

Stein, Steven L.; Lesperance, Ann M.; Upton, Jaki F.

2010-02-01

On October 9, 2008, federal, state and local policy makers, emergency managers, and medical and public health officials convened in Seattle, Washington, for a workshop on Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack. The day-long symposium was aimed at generating a dialogue about recovery and restoration through a discussion of the associated challenges that impact entire communities, including people, infrastructure, and critical systems. The Principal Federal Official (PFO) provided an overview of the role of the PFO in a catastrophic event. A high-level summary of an anthrax scenario was presented. The remainder of the day was focused on interactive discussions among federal, state and local emergency management experts in the areas of: • Decision-making, prioritization, and command and control • Public health/medical services • Community resiliency and continuity of government. Key topics and issues that resulted from discussions included: • Local representation in the Joint Field Office (JFO) • JFO transition to the Long-Term Recovery Office • Process for prioritization of needs • Process for regional coordination • Prioritization - process and federal/military intervention • Allocation of limited resources • Re-entry decision and consistency • Importance of maintaining a healthy hospital system • Need for a process to establish a consensus on when it is safe to re-enter. This needs to be across all jurisdictions including the military. • Insurance coverage for both private businesses and individuals • Interaction between the government and industry. The symposium was sponsored by the Interagency Biological Restoration Demonstration, a collaborative regional program jointly funded by the U.S. Department of Homeland Security and the U.S. Department of Defense. To aid the program’s efforts and inform the development of blueprint for recovery from a biological incident

Treatment of the loss of ultimate heat sink initiating events in the IRSN level 1 PSA

International Nuclear Information System (INIS)

Dupuy, Patricia; Georgescu, Gabriel; Corenwinder, Francois

2014-01-01

The total loss of the ultimate heat sink is an initiating event which, even it is mainly of external origin, has been considered in the frame of internal events Level 1 PSA by IRSN. The on-going actions on the development of external hazards PSA and the recent incident of loss of the heat sink induced by the ingress of vegetable matter that occurred in France in 2009 have pointed out the need to improve the modeling of the loss of the heat sink initiating event and sequences to better take into account the fact that this loss may be induced by external hazards and thus affect all the site units. The paper presents the historical steps of the modeling of the total loss of the heat sink, the safety stakes of this modeling, the main assumptions used by IRSN in the associated PSA for the 900 MWe reactors and the results obtained. The total loss of the heat sink was not initially addressed in the safety demonstration of French NPPs. On the basis of the insights of the first probabilistic assessments performed in the 80's, the risks associated to this 'multiple failure situation' turned out to be very significant and design and organisational improvements were implemented on the plants. Reviews of the characterization of external hazards and of their consequences on the installations and French operating feedback have revealed that extreme hazards may induce a total loss of the heat sink. Moreover, the accident that occurred at Fukushima in 2011 has pointed out the risk of such a loss of long duration at all site units in case of extreme hazards. In this context, it seems relevant to further improve the modelling of the total loss of the heat sink by considering the external hazards that may cause this loss. In a first step, IRSN has improved the assumptions and data used in the loss of the heat sink PSA model, in particular by considering that such a loss may affect all the site units. The next challenge will be the deeper analysis of the impact of external hazards on

Development and verification of an efficient spatial neutron kinetics method for reactivity-initiated event analyses

International Nuclear Information System (INIS)

Ikeda, Hideaki; Takeda, Toshikazu

2001-01-01

A space/time nodal diffusion code based on the nodal expansion method (NEM), EPISODE, was developed in order to evaluate transient neutron behavior in light water reactor cores. The present code employs the improved quasistatic (IQS) method for spatial neutron kinetics, and neutron flux distribution is numerically obtained by solving the neutron diffusion equation with the nonlinear iteration scheme to achieve fast computation. A predictor-corrector (PC) method developed in the present study enabled to apply a coarse time mesh to the transient spatial neutron calculation than that applicable in the conventional IQS model, which improved computational efficiency further. Its computational advantage was demonstrated by applying to the numerical benchmark problems that simulate reactivity-initiated events, showing reduction of computational times up to a factor of three than the conventional IQS. The thermohydraulics model was also incorporated in EPISODE, and the capability of realistic reactivity event analyses was verified using the SPERT-III/E-Core experimental data. (author)

Charged particle multiplicities in heavy and light quark initiated events above the $Z^0$ peak

CERN Document Server

Abbiendi, G.; Akesson, P.F.; Alexander, G.; Allison, John; Amaral, P.; Anagnostou, G.; Anderson, K.J.; Arcelli, S.; Asai, S.; Axen, D.; Azuelos, G.; Bailey, I.; Barberio, E.; Barlow, R.J.; Batley, R.J.; Bechtle, P.; Behnke, T.; Bell, Kenneth Watson; Bell, P.J.; Bella, G.; Bellerive, A.; Benelli, G.; Bethke, S.; Biebel, O.; Bloodworth, I.J.; Boeriu, O.; Bock, P.; Bonacorsi, D.; Boutemeur, M.; Braibant, S.; Brigliadori, L.; Brown, Robert M.; Buesser, K.; Burckhart, H.J.; Campana, S.; Carnegie, R.K.; Caron, B.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Csilling, A.; Cuffiani, M.; Dado, S.; Dallison, S.; De Roeck, A.; De Wolf, E.A.; Desch, K.; Dienes, B.; Donkers, M.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Elfgren, E.; Etzion, E.; Fabbri, F.; Feld, L.; Ferrari, P.; Fiedler, F.; Fleck, I.; Ford, M.; Frey, A.; Furtjes, A.; Gagnon, P.; Gary, John William; Gaycken, G.; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Giunta, Marina; Goldberg, J.; Gross, E.; Grunhaus, J.; Gruwe, M.; Gunther, P.O.; Gupta, A.; Hajdu, C.; Hamann, M.; Hanson, G.G.; Harder, K.; Harel, A.; Harin-Dirac, M.; Hauschild, M.; Hauschildt, J.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Hensel, C.; Herten, G.; Heuer, R.D.; Hill, J.C.; Hoffman, Kara Dion; Homer, R.J.; Horvath, D.; Howard, R.; Igo-Kemenes, P.; Ishii, K.; Jeremie, H.; Jovanovic, P.; Junk, T.R.; Kanaya, N.; Kanzaki, J.; Karapetian, G.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kim, D.H.; Klein, K.; Klier, A.; Kluth, S.; Kobayashi, T.; Kobel, M.; Komamiya, S.; Kormos, Laura L.; Kramer, T.; Kress, T.; Krieger, P.; von Krogh, J.; Krop, D.; Kruger, K.; Kuhl, T.; Kupper, M.; Lafferty, G.D.; Landsman, H.; Lanske, D.; Layter, J.G.; Leins, A.; Lellouch, D.; Lettso, J.; Levinson, L.; Lillich, J.; Lloyd, S.L.; Loebinger, F.K.; Lu, J.; Ludwig, J.; Macpherson, A.; Mader, W.; Marcellini, S.; Marchant, T.E.; Martin, A.J.; Martin, J.P.; Masetti, G.; Mashimo, T.; Mattig, Peter; McDonald, W.J.; McKenna, J.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Mendez-Lorenzo, P.; Menges, W.; Merritt, F.S.; Mes, H.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D.J.; Moed, S.; Mohr, W.; Mori, T.; Mutter, A.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nisius, R.; O'Neale, S.W.; Oh, A.; Okpara, A.; Oreglia, M.J.; Orito, S.; Pahl, C.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poli, B.; Polok, J.; Pooth, O.; Przybycien, M.; Quadt, A.; Rabbertz, K.; Rembser, C.; Renkel, P.; Rick, H.; Roney, J.M.; Rosati, S.; Rozen, Y.; Runge, K.; Sachs, K.; Saeki, T.; Sahr, O.; Sarkisyan, E.K.G.; Schaile, A.D.; Schaile, O.; Scharff-Hansen, P.; Schieck, J.; Schoerner-Sadenius, Thomas; Schroder, Matthias; Schumacher, M.; Schwick, C.; Scott, W.G.; Seuster, R.; Shears, T.G.; Shen, B.C.; Sherwood, P.; Siroli, G.; Skuja, A.; Smith, A.M.; Sobie, R.; Soldner-Rembold, S.; Spano, F.; Stahl, A.; Stephens, K.; Strom, David M.; Strohmer, R.; Tarem, S.; Tasevsky, M.; Taylor, R.J.; Teuscher, R.; Thomson, M.A.; Torrence, E.; Toya, D.; Tran, P.; Trefzger, T.; Tricoli, A.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turner-Watson, M.F.; Ueda, I.; Ujvari, B.; Vachon, B.; Vollmer, C.F.; Vannerem, P.; Verzocchi, M.; Voss, H.; Vossebeld, J.; Waller, D.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wengler, T.; Wermes, N.; Wetterling, D.; Wilson, G.W.; Wilson, J.A.; Wolf, G.; Wyatt, T.R.; Yamashita, S.; Zer-Zion, D.; Zivkovic, Lidija

2002-01-01

We have measured the mean charged particle multiplicities separately for bbbar, ccbar and light quark (uubar, ddbar, ssbar) initiated events produced in e+e- annihilations at LEP. The data were recorded with the OPAL detector at eleven different energies above Z0 peak, corresponding to the full statistics collected at LPE1.5 and LEP2. The difference in mean charged and particle multiplicities for bbbar and light quark events, delta_bl, measured over this energy range is consistent with an energy independent behaviour, as predicted by QCD, but is inconsistent with the prediction of a more phenomenological approach which assumes that the multiplicity accompanying the decay of a heavy quark is independent of the quark mass itself. Our results, which can be combined into the single measurement delta_bl = 3.44+-0.40(stat)+-0.89(syst) at a luminosity weighted average centre-of mass energy of 195 GeV, are also consistent with an energy independent behaviour as extrapolated from lower energy data.

Detecting measurement-induced relative-position localization

International Nuclear Information System (INIS)

Knott, P A; Sindt, J; Dunningham, J A

2013-01-01

The theory of decoherence explains how classicality emerges from an underlying quantum reality. An additional interpretation to this has been proposed in which scattering events induce the localization of relative observables (Rau et al 2003 Science 301 1081). An interesting consequence of this process is that it involves the build-up of certain robust entanglements between the observables being localized. To date the weakness of this interpretation has been the lack of a clear experimental signature that allows it to be tested. Here we provide a simple experimentally accessible scheme that enables just that. We also discuss a Bayesian technique that could, in principle, allow experiments to confirm the localization to any desired degree of accuracy and we present precision requirements that are achievable with current experiments. Finally, we extend the scheme from its initial one dimensional proof of principle to the more real world scenario of three dimensional localization. (paper)

Study of Updating Initiating Event Frequency using Prognostics

Energy Technology Data Exchange (ETDEWEB)

Kim, Hyeonmin; Lee, Sang-Hwan; Park, Jun-seok; Kim, Hyungdae; Chang, Yoon-Suk; Heo, Gyunyoung [Kyung Hee Univ., Yongin (Korea, Republic of)

2014-10-15

The Probabilistic Safety Assessment (PSA) model enables to find the relative priority of accident scenarios, weak points in achieving accident prevention or mitigation, and insights to improve those vulnerabilities. Thus, PSA consider realistic calculation for precise and confidence results. However, PSA model still 'conservative' aspects in the procedures of developing a PSA model. One of the sources for the conservatism is caused by the assumption of safety analysis and the estimation of failure frequency. Recently, Surveillance, Diagnosis, and Prognosis (SDP) is a growing trend in applying space and aviation systems in particular. Furthermore, a study dealing with the applicable areas and state-of-the-art status of the SDP in nuclear industry was published. SDP utilizing massive database and information technology among such enabling techniques is worthwhile to be highlighted in terms of the capability of alleviating the conservatism in the conventional PSA. This paper review the concept of integrating PSA and SDP and suggest the updated methodology of Initiating Event (IE) using prognostics. For more detailed, we focus on IE of the Steam Generator Tube Rupture (SGTR) considering tube degradation. This paper is additional research of previous our suggested the research. In this paper, the concept of integrating PSA and SDP are suggested. Prognostics algorithms in SDP are applied at IE, Bes in the Level 1 PSA. As an example, updating SGTR IE and its ageing were considered. Tube ageing were analyzed by using PASTA and Monte Carlo method. After analyzing the tube ageing, conventional SGTR IE were updated by using Bayesian approach. The studied method can help to cover the static and conservatism in PSA.

Study of Updating Initiating Event Frequency using Prognostics

International Nuclear Information System (INIS)

Kim, Hyeonmin; Lee, Sang-Hwan; Park, Jun-seok; Kim, Hyungdae; Chang, Yoon-Suk; Heo, Gyunyoung

2014-01-01

The Probabilistic Safety Assessment (PSA) model enables to find the relative priority of accident scenarios, weak points in achieving accident prevention or mitigation, and insights to improve those vulnerabilities. Thus, PSA consider realistic calculation for precise and confidence results. However, PSA model still 'conservative' aspects in the procedures of developing a PSA model. One of the sources for the conservatism is caused by the assumption of safety analysis and the estimation of failure frequency. Recently, Surveillance, Diagnosis, and Prognosis (SDP) is a growing trend in applying space and aviation systems in particular. Furthermore, a study dealing with the applicable areas and state-of-the-art status of the SDP in nuclear industry was published. SDP utilizing massive database and information technology among such enabling techniques is worthwhile to be highlighted in terms of the capability of alleviating the conservatism in the conventional PSA. This paper review the concept of integrating PSA and SDP and suggest the updated methodology of Initiating Event (IE) using prognostics. For more detailed, we focus on IE of the Steam Generator Tube Rupture (SGTR) considering tube degradation. This paper is additional research of previous our suggested the research. In this paper, the concept of integrating PSA and SDP are suggested. Prognostics algorithms in SDP are applied at IE, Bes in the Level 1 PSA. As an example, updating SGTR IE and its ageing were considered. Tube ageing were analyzed by using PASTA and Monte Carlo method. After analyzing the tube ageing, conventional SGTR IE were updated by using Bayesian approach. The studied method can help to cover the static and conservatism in PSA

Simulating single-event burnout of n-channel power MOSFET's

International Nuclear Information System (INIS)

Johnson, G.H.; Hohl, J.H.; Schrimpf, R.D.; Galloway, K.F.

1993-01-01

Heavy ions are ubiquitous in a space environment. Single-event burnout of power MOSFET's is a sudden catastrophic failure mechanism that is initiated by the passage of a heavy ion through the device structure. The passage of the heavy ion generates a current filament that locally turns on a parasitic n-p-n transistor inherent to the power MOSFET. Subsequent high currents and high voltage in the device induce second breakdown of the parasitic bipolar transistor and hence meltdown of the device. This paper presents a model that can be used for simulating the burnout mechanism in order to gain insight into the significant device parameters that most influence the single-event burnout susceptibility of n-channel power MOSFET's

CDC/NACCHO Accreditation Support Initiative: advancing readiness for local and tribal health department accreditation.

Science.gov (United States)

Monteiro, Erinn; Fisher, Jessica Solomon; Daub, Teresa; Zamperetti, Michelle Chuk

2014-01-01

Health departments have various unique needs that must be addressed in preparing for national accreditation. These needs require time and resources, shortages that many health departments face. The Accreditation Support Initiative's goal was to test the assumption that even small amounts of dedicated funding can help health departments make important progress in their readiness to apply for and achieve accreditation. Participating sites' scopes of work were unique to the needs of each site and based on the proposed activities outlined in their applications. Deliverables and various sources of data were collected from sites throughout the project period (December 2011-May 2012). Awardees included 1 tribal and 12 local health departments, as well as 5 organizations supporting the readiness of local and tribal health departments. Sites dedicated their funding toward staff time, accreditation fees, completion of documentation, and other accreditation readiness needs and produced a number of deliverables and example documents. All sites indicated that they made accreditation readiness gains that would not have occurred without this funding. Preliminary evaluation data from the first year of the Accreditation Support Initiative indicate that flexible funding arrangements may be an effective way to increase health departments' accreditation readiness.

Event Shape Sorting: selecting events with similar evolution

Directory of Open Access Journals (Sweden)

Tomášik Boris

2017-01-01

Full Text Available We present novel method for the organisation of events. The method is based on comparing event-by-event histograms of a chosen quantity Q that is measured for each particle in every event. The events are organised in such a way that those with similar shape of the Q-histograms end-up placed close to each other. We apply the method on histograms of azimuthal angle of the produced hadrons in ultrarelativsitic nuclear collisions. By selecting events with similar azimuthal shape of their hadron distribution one chooses events which are likely that they underwent similar evolution from the initial state to the freeze-out. Such events can more easily be compared to theoretical simulations where all conditions can be controlled. We illustrate the method on data simulated by the AMPT model.

Risk factors for adverse events after vaccinations performed during the initial hospitalization of infants born prematurely.

Science.gov (United States)

Wilińska, Maria; Warakomska, Małgorzata; Głuszczak-Idziakowska, Ewa; Jackowska, Teresa

There are significant delays in implementing vaccination among preterm infants. Description of the frequency and kinds of adverse events following immunization in preterms. Establishment of the group of preterms who will distinctively be susceptible to adverse events. Demographical, clinical data and the occurrence of adverse events after DTaP, HIB and pneumococcal vaccination among preterms during their initial hospitalization were prospectively collected with the use of an electronic data form between 1st June 2011 and 31st May 2015. The analysis was conducted on 138 patients. The groups were divided according to maturity (I: ≤ GA 28w n=73 and GA 29-36 w n=65). There were no statistically significant differences between the groups in the occurrence of adverse events. Out of the total group, following vaccination apnoea developed in 6 newborns (4%) and activity dysfunctions were observed in 13 newborns (10%). The occurrence of apnoea after vaccination positively correlated with the time of non-invasive ventilation and the occurrence of late infection. There were no statistically significant demographical or clinical risk factors for the development of activity dysfunctions following vaccination. Term vaccination in clinically stable preterm infants is a safe medical procedure. However, long-term non-invasive respiratory support and late infections are risk factors for apnea following vaccinations. In these patients vaccinations should be considered during hospitalization.

Probabilistic safety analysis on an SBWR 72 hours after the initiating event

International Nuclear Information System (INIS)

Dominguez Bautista, M.T.; Peinador Veira, M.

1996-01-01

Passive plants, including SBWRs, are designed to carry out safety functions with passive systems during the first 72 hours after the initiation event with no need for manual actions or external support. After this period, some recovery actions are required to enable the passive systems to continue performing their safety functions. The study was carried out by the INITEC-Empresarios Agrupados Joint Venture within the framework of the international group collaborating with GE on this project. Its purpose has been to assess, by means of probabilistic criteria, the importance to safety of each of these support actions, in order to define possible requirements to be considered in the design in respect of said recovery actions. In brief, the methodology developed for this objective consists of (1) quantifying success event trees from the PSA up to 72 hours, (2) determining the actions required in each sequence to maintain Steady State after 72 hours, (3) identifying available alternative core cooling methods in each sequence, (4) establishing the approximate (order of magnitude) realizability of each alternative method, (5) calculating the frequency of core damage as a function of the failure probability of post-72-hour actions and (6) analysing the importance of post-72-hour actions. The results of this analysis permit the establishment, right from the conceptual design phase, of the requirements that will arise to ensure these actions in the long term, enhancing their reliability and preventing the accident from continuing beyond this period. (Author)

Selection of important initiating events for Level 1 probabilistic safety assessment study at Puspati TRIGA Reactor

International Nuclear Information System (INIS)

Maskin, M.; Charlie, F.; Hassan, A.; Prak Tom, P.; Ramli, Z.; Mohamed, F.

2016-01-01

Highlights: • Identifying possible important initiating events (IEs) for Level 1 probabilistic safety assessment performed on research nuclear reactor. • Methods in screening and grouping IEs are addressed. • Focusing only on internal IEs due to random failures of components. - Abstract: This paper attempts to present the results in identifying possible important initiating events (IEs) as comprehensive as possible to be applied in the development of Level-1 probabilistic safety assessment (PSA) study. This involves the approaches in listing and the methods in screening and grouping IEs, by focusing only on the internal IEs due to random failures of components and human errors with full power operational conditions and reactor core as the radioactivity source. Five approaches were applied in listing the IEs and each step of the methodology was described and commented. The criteria in screening and grouping the IEs were also presented. The results provided the information on how the Malaysian PSA team applied the approaches in selecting the most probable IEs as complete as possible in order to ensure the set of IEs was identified systematically and as representative as possible, hence providing confidence to the completeness of the PSA study. This study is perhaps one of the first to address classic comprehensive steps in identifying important IEs to be used in a Level-1 PSA study.

Event classification related to overflow of solvent containing uranium according to the INES scale (International Nuclear and Radiological Event Scale)

International Nuclear Information System (INIS)

Dourado, Eneida R.G.; Assis, Juliana T. de; Lage, Ricardo F.; Lopes, Karina B.

2013-01-01

This paper aims to frame the event overflow organic solvent rich in uranium, from a decanter of ore beneficiation plant, caused by the fall in the supply of electricity, according to the criteria established by the International Nuclear Event Scale and radiological (INES), facilitating the understanding of the occurrence and communication with the public regarding the radiation safety aspects involved. With the fall of electricity, routine procedures in situations of installation stop were performed, however, due to operational failure, the valve on the transfer line liquor was not closed. Thus, the mixer continued being fed with liquor, that led the consequent leakage of solvent loaded with uranium. It reached the drainage system, and the box of rainwater harvesting of the plant. However, immediately after the detection of the event, corrective actions were initiated and the overflow was contained. Regulatory agencies followed the removal of the solvent and on the results of the analysis of environmental monitoring, found that the event did not provide exposure to workers or any other impact. Therefore, comparing the characteristics of the event and the guidelines proposed by the INES scale, it is concluded that the classification of the event is below scale/level 0, confirming the absence of risk to the local population, workers and the environment

On the initiation of sustained slip-weakening ruptures by localized stresses

KAUST Repository

Galis, Martin

2014-12-10

Numerical simulations of dynamic earthquake rupture require an artificial initiation procedure, if they are not integrated in long-term earthquake cycle simulations. A widely applied procedure involves an \\'overstressed asperity\\', a localized region stressed beyond the static frictional strength. The physical properties of the asperity (size, shape and overstress) may significantly impact rupture propagation. In particular, to induce a sustained rupture the asperity size needs to exceed a critical value. Although criteria for estimating the critical nucleation size under linear slip-weakening friction have been proposed for 2-D and 3-D problems based on simplifying assumptions, they do not provide general rules for designing 3-D numerical simulations. We conduct a parametric study to estimate parameters of the asperity that minimize numerical artefacts (e.g. changes of rupture shape and speed, artificial supershear transition, higher slip-rate amplitudes). We examine the critical size of square, circular and elliptical asperities as a function of asperity overstress and background (off-asperity) stress. For a given overstress, we find that asperity area controls rupture initiation while asperity shape is of lesser importance. The critical area obtained from our numerical results contrasts with published theoretical estimates when background stress is low. Therefore, we derive two new theoretical estimates of the critical size under low background stress while also accounting for overstress. Our numerical results suggest that setting the asperity overstress and area close to their critical values eliminates strong numerical artefacts even when the overstress is large. We also find that properly chosen asperity size or overstress may significantly shorten the duration of the initiation. Overall, our results provide guidelines for determining the size of the asperity and overstress to minimize the effects of the forced initiation on the subsequent spontaneous

Summary of significant solar-initiated events during STIP interval XII

International Nuclear Information System (INIS)

Gergely, T.E.

1982-01-01

A summary of the significant solar-terrestrial events of STIP Interval XII (April 10-July 1, 1981) is presented. It is shown that the first half of the interval was extremely active, with several of the largest X-ray flares, particle events, and shocks of this solar cycle taking place during April and the first half of May. However, the second half of the interval was characterized by relatively quiet conditions. A detailed examination is presented of several large events which occurred on 10, 24, and 27 April and on 8 and 16 May. It is suggested that the comparison and statistical analysis of the numerous events for which excellent observations are available could provide information on what causes a type II burst to propagate in the interplanetary medium

Initiating events of accidents in the practice of oil well logging in Cuba

International Nuclear Information System (INIS)

Alles Leal, A.; Perez Reyes, Y.; Dumenigo Gonzalez, C.

2013-01-01

The oil well logging is an extremely important activity within the oil industry, but in turn, brings risks that occasionally result in damage to health, the environment and economic losses. In this context, risk analysis has become an important tool to control them through their prediction and the study of the factors that determine them, enabling substantiated decisions to, first, foresee accidents and, secondly, to minimize their consequences. This paper proposes the elaboration of a list of initiating events of accidents in the practice of oil well logging which is one of the most important aspects for further evaluation of radiation safety of this practice. For its determination the technique employed to identify risks was 'Failure Modes and Effects Analysis (FMEA)' by applying it to the different stages and processes of practice. (Author)

78 FR 33700 - Special Local Regulations for Marine Events, Pleasantville Aquatics 15th Annual 5K Open Water...

Science.gov (United States)

2013-06-05

...-AA08 Special Local Regulations for Marine Events, Pleasantville Aquatics 15th Annual 5K Open Water Swim... Waterway for the Pleasantville Aquatics 15th Annual 5K Open Water Swim. The Captain of the Port, Sector..., Pleasantville Aquatics 15th Annual 5K Open Water Swim, Intracoastal Waterway; Atlantic City, NJ. (a) Location...

Treatment of external events in the linked event tree methodology NPP Goesgen - Daeniken example

International Nuclear Information System (INIS)

Kozlik, Thomas

2014-01-01

The NPP Goesgen-Daeniken uses a combined level 1 / level 2 PSA model for its event analyses. The model uses a linked event tree approach, using the software RISKMAN R . Each initiating event passes through a modularized event tree structure, consisting of external events pre-trees, alignment and support systems trees and front-line and containment response trees. This paper explains the structure of the linked event trees. Switches are used to bypass certain trees for specific initiating events. The screening process applied to possible external events is explained. The final scope of considered natural external events in the Goesgen PSA consists of earthquakes, seasonal events causing cooling water intake plugging or external floods. The structure of the natural external events pre-trees is explained. The treatment of external floods is explained in more detail. Floods at the Goesgen site are caused by extreme river flows into the old branch of the Aare river. A new model has been developed to analyse the probabilistic flood hazard using a bivariate distribution (water level and flood duration). Analysing the statistical data, the time trend had to be considered. The Goesgen PSA models 7 external flood initiating events, considering different water levels and durations at the flooded plant site. The building fragilities were developed in terms of resistance times. The RISKMAN R external flood pre-tree consists of top events for operator actions and failure of the building functions, which leads to the functional failure of equipment located at the lower elevation of the building. (author)

Coupled prediction of flood response and debris flow initiation during warm- and cold-season events in the Southern Appalachians, USA

Science.gov (United States)

Tao, J.; Barros, A. P.

2014-01-01

Debris flows associated with rainstorms are a frequent and devastating hazard in the Southern Appalachians in the United States. Whereas warm-season events are clearly associated with heavy rainfall intensity, the same cannot be said for the cold-season events. Instead, there is a relationship between large (cumulative) rainfall events independently of season, and thus hydrometeorological regime, and debris flows. This suggests that the dynamics of subsurface hydrologic processes play an important role as a trigger mechanism, specifically through soil moisture redistribution by interflow. We further hypothesize that the transient mass fluxes associated with the temporal-spatial dynamics of interflow govern the timing of shallow landslide initiation, and subsequent debris flow mobilization. The first objective of this study is to investigate this relationship. The second objective is to assess the physical basis for a regional coupled flood prediction and debris flow warning system. For this purpose, uncalibrated model simulations of well-documented debris flows in headwater catchments of the Southern Appalachians using a 3-D surface-groundwater hydrologic model coupled with slope stability models are examined in detail. Specifically, we focus on two vulnerable headwater catchments that experience frequent debris flows, the Big Creek and the Jonathan Creek in the Upper Pigeon River Basin, North Carolina, and three distinct weather systems: an extremely heavy summertime convective storm in 2011; a persistent winter storm lasting several days; and a severe winter storm in 2009. These events were selected due to the optimal availability of rainfall observations; availability of detailed field surveys of the landslides shortly after they occurred, which can be used to evaluate model predictions; and because they are representative of events that cause major economic losses in the region. The model results substantiate that interflow is a useful prognostic of conditions

Robust Initial Wetness Condition Framework of an Event-Based Rainfall–Runoff Model Using Remotely Sensed Soil Moisture

OpenAIRE

Wooyeon Sunwoo; Minha Choi

2017-01-01

Runoff prediction in limited-data areas is vital for hydrological applications, such as the design of infrastructure and flood defenses, runoff forecasting, and water management. Rainfall–runoff models may be useful for simulation of runoff generation, particularly event-based models, which offer a practical modeling scheme because of their simplicity. However, there is a need to reduce the uncertainties related to the estimation of the initial wetness condition (IWC) prior to a rainfall even...

Analytic expressions for the construction of a fire event PSA model

International Nuclear Information System (INIS)

Kang, Dae Il; Kim, Kil Yoo; Kim, Dong San; Hwang, Mee Jeong; Yang, Joon Eon

2016-01-01

In this study, the changing process of an internal event PSA model to a fire event PSA model is analytically presented and discussed. Many fire PSA models have fire induced initiating event fault trees not shown in an internal event PSA model. Fire-induced initiating fault tree models are developed for addressing multiple initiating event issues. A single fire event within a fire compartment or fire scenario can cause multiple initiating events. As an example, a fire in a turbine building area can cause a loss of the main feed-water and loss of off-site power initiating events. Up to now, there has been no analytic study on the construction of a fire event PSA model using an internal event PSA model with fault trees of initiating events. In this paper, the changing process of an internal event PSA model to a fire event PSA model was analytically presented and discussed. This study results show that additional cutsets can be obtained if the fault trees of initiating events for a fire event PSA model are not exactly developed.

Analytic expressions for the construction of a fire event PSA model

Energy Technology Data Exchange (ETDEWEB)

Kang, Dae Il; Kim, Kil Yoo; Kim, Dong San; Hwang, Mee Jeong; Yang, Joon Eon [KAERI, Daejeon (Korea, Republic of)

2016-05-15

In this study, the changing process of an internal event PSA model to a fire event PSA model is analytically presented and discussed. Many fire PSA models have fire induced initiating event fault trees not shown in an internal event PSA model. Fire-induced initiating fault tree models are developed for addressing multiple initiating event issues. A single fire event within a fire compartment or fire scenario can cause multiple initiating events. As an example, a fire in a turbine building area can cause a loss of the main feed-water and loss of off-site power initiating events. Up to now, there has been no analytic study on the construction of a fire event PSA model using an internal event PSA model with fault trees of initiating events. In this paper, the changing process of an internal event PSA model to a fire event PSA model was analytically presented and discussed. This study results show that additional cutsets can be obtained if the fault trees of initiating events for a fire event PSA model are not exactly developed.

From Family Based to Industrial Based Production: Local Economic Development Initiatives and the HELIX Model

Directory of Open Access Journals (Sweden)

Bartjan W Pennink

2013-01-01

Full Text Available To build a strong local economy, good practice tells us that each community should undertake a collaborative, strategically planned process to understand and then act upon its own strengths, weaknesses, opportunities and threats. From this perspective we start with the local communities but how is this related to the perspective from the Helix model in which three actors are explicitly introduced: the Government, the Industry and the Universities? The purpose of local economic development (LED is to build up the economic capacity of a local area to improve its economic future and the quality of life for all. To support  the Local Economic Development in remote areas,   a program  has been developed based on the LED frame work of the world bank. This approach and  the experiences over  the past years with this program are  described in the first part.  In the second part of the paper, We analyse work done with that program with the help of the social capital concept and the triple helix model.  In all cases it is important to pay attention to who is taken the initiative after the first move (and it is not always the governance as actor and for the triple helix we suggest  that the concepts of (national Government, Industry and University need a translation to Local Governance Agency, Cooperation or other ways of cooperation of local communities and Local Universities. Although a push from outside might help  a local region in development the endogenous factors are  also needed. Keywords: Triple Helix model, Local Economic Development, Local Actors, Double Triangle within the Helix Model

Biomagnetic localization from transient quasi-static events

Energy Technology Data Exchange (ETDEWEB)

Mosher, J.C.; Leahy, R.M.; Lewis, P.S. [Los Alamos National Lab., NM (United States)]|[University of Southern California, Los Angeles, CA (United States). Signal and Image Processing Inst.

1993-02-01

Sensory stimuli, such as auditory, visual, or somatosensory, evoke neural responses in very localized regions of the brain. A SQUID biomagnetometer can measure the very weak fields that are generated outside of the head by this response. A simple source and head model of current dipoles inside a conducting sphere is typically used to interpret these magnetic field measurements or magnetoencephalogram (MEG). Locating dipole sources using data recorded from an array of biomagnetic sensors is distinguished from conventional array source localization techniques by the quasi-static transient nature of the data. Here, the basic MEG model is reviewed, then a localization example is given to motivate the need for partitioning the data to improve estimator performance. Tune-eigenspectrum analysis is introduced as a means of partitioning and interpreting spatio-temporal biomagnetic data. Examples using both simulated and somatosensory data are presented.

Biomagnetic localization from transient quasi-static events

Energy Technology Data Exchange (ETDEWEB)

Mosher, J.C.; Leahy, R.M.; Lewis, P.S. (Los Alamos National Lab., NM (United States) University of Southern California, Los Angeles, CA (United States). Signal and Image Processing Inst.)

1993-01-01

Sensory stimuli, such as auditory, visual, or somatosensory, evoke neural responses in very localized regions of the brain. A SQUID biomagnetometer can measure the very weak fields that are generated outside of the head by this response. A simple source and head model of current dipoles inside a conducting sphere is typically used to interpret these magnetic field measurements or magnetoencephalogram (MEG). Locating dipole sources using data recorded from an array of biomagnetic sensors is distinguished from conventional array source localization techniques by the quasi-static transient nature of the data. Here, the basic MEG model is reviewed, then a localization example is given to motivate the need for partitioning the data to improve estimator performance. Tune-eigenspectrum analysis is introduced as a means of partitioning and interpreting spatio-temporal biomagnetic data. Examples using both simulated and somatosensory data are presented.

Improving linear accelerator service response with a real- time electronic event reporting system.

Science.gov (United States)

Hoisak, Jeremy D P; Pawlicki, Todd; Kim, Gwe-Ya; Fletcher, Richard; Moore, Kevin L

2014-09-08

To track linear accelerator performance issues, an online event recording system was developed in-house for use by therapists and physicists to log the details of technical problems arising on our institution's four linear accelerators. In use since October 2010, the system was designed so that all clinical physicists would receive email notification when an event was logged. Starting in October 2012, we initiated a pilot project in collaboration with our linear accelerator vendor to explore a new model of service and support, in which event notifications were also sent electronically directly to dedicated engineers at the vendor's technical help desk, who then initiated a response to technical issues. Previously, technical issues were reported by telephone to the vendor's call center, which then disseminated information and coordinated a response with the Technical Support help desk and local service engineers. The purpose of this work was to investigate the improvements to clinical operations resulting from this new service model. The new and old service models were quantitatively compared by reviewing event logs and the oncology information system database in the nine months prior to and after initiation of the project. Here, we focus on events that resulted in an inoperative linear accelerator ("down" machine). Machine downtime, vendor response time, treatment cancellations, and event resolution were evaluated and compared over two equivalent time periods. In 389 clinical days, there were 119 machine-down events: 59 events before and 60 after introduction of the new model. In the new model, median time to service response decreased from 45 to 8 min, service engineer dispatch time decreased 44%, downtime per event decreased from 45 to 20 min, and treatment cancellations decreased 68%. The decreased vendor response time and reduced number of on-site visits by a service engineer resulted in decreased downtime and decreased patient treatment cancellations.

Impact of soil moisture initialization on boreal summer subseasonal forecasts: mid-latitude surface air temperature and heat wave events

Science.gov (United States)

Seo, Eunkyo; Lee, Myong-In; Jeong, Jee-Hoon; Koster, Randal D.; Schubert, Siegfried D.; Kim, Hye-Mi; Kim, Daehyun; Kang, Hyun-Suk; Kim, Hyun-Kyung; MacLachlan, Craig; Scaife, Adam A.

2018-05-01

This study uses a global land-atmosphere coupled model, the land-atmosphere component of the Global Seasonal Forecast System version 5, to quantify the degree to which soil moisture initialization could potentially enhance boreal summer surface air temperature forecast skill. Two sets of hindcast experiments are performed by prescribing the observed sea surface temperature as the boundary condition for a 15-year period (1996-2010). In one set of the hindcast experiments (noINIT), the initial soil moisture conditions are randomly taken from a long-term simulation. In the other set (INIT), the initial soil moisture conditions are taken from an observation-driven offline Land Surface Model (LSM) simulation. The soil moisture conditions from the offline LSM simulation are calibrated using the forecast model statistics to minimize the inconsistency between the LSM and the land-atmosphere coupled model in their mean and variability. Results show a higher boreal summer surface air temperature prediction skill in INIT than in noINIT, demonstrating the potential benefit from an accurate soil moisture initialization. The forecast skill enhancement appears especially in the areas in which the evaporative fraction—the ratio of surface latent heat flux to net surface incoming radiation—is sensitive to soil moisture amount. These areas lie in the transitional regime between humid and arid climates. Examination of the extreme 2003 European and 2010 Russian heat wave events reveal that the regionally anomalous soil moisture conditions during the events played an important role in maintaining the stationary circulation anomalies, especially those near the surface.

Radiation or chemoradiation: initial utility study of selected therapy for local advanced stadium cervical cancer

Science.gov (United States)

Pramitasari, D. A.; Gondhowiardjo, S.; Nuranna, L.

2017-08-01

This study aimed to compare radiation only or chemo radiation treatment of local advanced cervical cancers by examining the initial response of tumors and acute side effects. An initial assessment employed value based medicine (VBM) by obtaining utility values for both types of therapy. The incidences of acute lower gastrointestinal, genitourinary, and hematology side effects in patients undergoing chemoradiation did not differ significantly from those undergoing radiation alone. Utility values for patients who underwent radiation alone were higher compared to those who underwent chemoradiation. It was concluded that the complete response of patients who underwent chemoradiation did not differ significantly from those who underwent radiation alone.

Using Local Event Tomography to Image Changes in the Rock Mass in the Kiirunavaara Iron Ore Mine, Northern Sweden

Science.gov (United States)

Lund, B.; Berglund, K.; Tryggvason, A.; Dineva, S.; Jonsson, L.

2017-12-01

Although induced seismic events in a mining environment are a potential hazard, they can be used to gain information about the rock mass in the mine which otherwise would be very difficult to obtain. In this study we use approximately 1.2 million mining induced seismic events in the Kiirunavaara iron ore mine in northernmost Sweden to image the rock mass using local event travel-time tomography. The Kiirunavaara mine is the largest underground iron ore mine in the world. The ore body is a magnetite sheet of 4 km length, with an average thickness of 80 m, which dips approximately 55° to the east. The events are of various origins such as shear slip on fractures, non-shear events and blasts, with magnitudes of up to 2.5. We use manually picked P- and S-wave arrival times from the routine processing in the tomography and we require that both phases are present at at least five geophones. For the tomography we use the 3D local earthquake tomography code PStomo_eq (Tryggvason et al., 2002), which we adjusted to the mining scale. The tomographic images show clearly defined regions of high and low velocities. Prominent low S-velocity zones are associated with mapped clay zones. Regions of ore where mining is ongoing and the near-ore tunnel infrastructure in the foot-wall also show generally low P- and S-velocities. The ore at depths below the current mining levels is imaged both as a low S-velocity zone but even more pronounced as a high Vp/Vs ratio zone. The tomography shows higher P- and S-velocities in the foot-wall away from the areas of mine infrastructure. We relocate all 1.2 million events in the new 3D velocity model. The relocation significantly enhances the clarity of the event distribution in space and we can much more easily identify seismically active structures, such as e.g. the deformation of the ore passes. The large number of events makes it possible to do detailed studies of the temporal evolution of stability in the mine. We present preliminary results

Technical basis document for external events

International Nuclear Information System (INIS)

OBERG, B.D.

2003-01-01

This document supports the Tank Farms Documented Safety Analysis and presents the technical basis for the FR-equencies of externally initiated accidents. The consequences of externally initiated events are discussed in other documents that correspond to the accident that was caused by the external event. The external events include aircraft crash, vehicle accident, range fire, and rail accident

Initial results of local grid control using wind farms with grid support

Energy Technology Data Exchange (ETDEWEB)

Soerensen, Poul; Hansen, Anca D.; Iov, F.; Blaabjerg, F.

2005-09-01

This report describes initial results with simulation of local grid control using wind farms with grid support. The focus is on simulation of the behaviour of the wind farms when they are isolated from the main grid and establish a local grid together with a few other grid components. The isolated subsystems used in the work presented in this report do not intend to simulate a specific subsystem, but they are extremely simplified single bus bar systems using only a few more components than the wind farm. This approach has been applied to make it easier to understand the dynamics of the subsystem. The main observation is that the fast dynamics of the wind turbines seem to be able to contribute significantly to the grid control, which can be useful where the wind farm is isolated with a subsystem from the main grid with surplus of generation. Thus, the fast down regulation of the wind farm using automatic frequency control can keep the subsystem in operation and thereby improve the reliability of the grid. (LN)

A successful local economic development-urban renewal initiative ...

African Journals Online (AJOL)

Despite the urgent need for local economic development in South Africa, Local Economic Development (LED) as area of professional endeavour/activity has largely failed to live up to this need. In this article, an alternative approach to local economic development, which involved a 'bottom-up' approach to urban renewal is ...

National strategy for suicide prevention in Japan: impact of a national fund on progress of developing systems for suicide prevention and implementing initiatives among local authorities.

Science.gov (United States)

Nakanishi, Miharu; Yamauchi, Takashi; Takeshima, Tadashi

2015-01-01

In Japan, the Cabinet Office released the 'General Principles of Suicide Prevention Policy' in 2007 and suggested nine initiatives. In 2009, a national fund was launched to help prefectures (the administrative divisions of Japan) and local authorities implement five categories of suicide-prevention programs. This paper examines the impact of the national fund on the establishment of the systems for suicide prevention and the implementation of these initiatives among local authorities. The present study included 1385 local authorities (79.5%) from all 47 prefectures that responded to the cross-sectional questionnaire survey. Improved suicide-prevention systems and the implementation of nine initiatives in April 2013 were observed among 265 local authorities (19.1%) that implemented 'Training of community service providers' and 'Public awareness campaigns'; 178 local authorities (12.9%) that implemented 'Face-to-face counseling', 'Training of community service providers' and 'Public awareness campaigns'; and 324 local authorities (23.4%) that implemented 'Trauma-informed policies and practices'. There was no significant difference in suicide-prevention systems and the implementation of nine initiatives between 203 local authorities (14.7%) that implemented only 'Public awareness campaigns' and 231 local authorities (16.7%) that did not implement any suicide-prevention programs. The results of our study suggest that the national fund promoted the establishment of community systems for suicide prevention and helped implement initiatives among local authorities. The national suicide-prevention strategy in Japan should explore a standard package of programs to guide community suicide-prevention efforts with a sustained workforce among local authorities. © 2014 The Authors. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology.

Local Perceptions of Climate Variability and Change in Tropical Forests of Papua, Indonesia

Directory of Open Access Journals (Sweden)

Manuel Boissière

2013-12-01

Full Text Available People everywhere experience changes and events that impact their lives. Knowing how they perceive, react, and adapt to climatic changes and events is helpful in developing strategies to support adaptation to climate change. Mamberamo in Papua, Indonesia, is a sparsely populated watershed of 7.8 million hectares possessing rich tropical forests. Our study compares scientific and traditional ecological knowledge (TEK on climate, and analyzes how local people in Mamberamo perceive and react to climatic variations. We compared meteorological data for the region with local views gathered through focus group discussions and interviews in six villages. We explored the local significance of seasonality, climate variability, and climate change. Mamberamo is subject to strikingly low levels of climatic variation; nonetheless local people highlighted certain problematic climate-related events such as floods and droughts. As our results illustrate, the implications vary markedly among villages. People currently consider climate variation to have little impact on their livelihoods when contrasted with other factors, e.g., logging, mining, infrastructure development, and political decentralization. Nonetheless, increased salinity of water supplies, crop loss due to floods, and reduced hunting success are concerns in specific villages. To gain local engagement, adaptation strategies should initially focus on factors that local people already judge important. Based on our results we demonstrate that TEK, and an assessment of local needs and concerns, provide practical insights for the development and promotion of locally relevant adaptation strategies. These insights offer a foundation for further engagement.

Special event planning for the emergency manager.

Science.gov (United States)

Gaynor, Peter T

2009-11-01

In the domain of emergency management and homeland security there is a lack of a formal planning process at the local level when it comes to special event planning. The unique nature of special event planning demands an understanding of the planning process for both traditional and non-traditional planning partners. This understanding will make certain that local governments apply due diligence when planning for the safety of the public. This paper offers a practical roadmap for planning at the local level. It will address those 'special events' that are beyond routine local events but not of a sufficient scale to be granted National Special Security Event status. Due to the infrequency of 'special events' in most communities, it is imperative that deliberate planning takes place. Upon conclusion, the reader will be able to construct a planning process tailored to the needs of their community, guide both traditional and non-traditional planning partners through the planning process, determine priorities, explore alternatives, plan for contingencies, conduct a confirmation brief, facilitate operations and assemble an after-action report and improvement plan.

Marketing research for organizers of sports events

Directory of Open Access Journals (Sweden)

Gašović Milan

2012-01-01

Full Text Available Marketing research, which provide the data and the information for the decision making process, are essential for organizers of sport events, especially to the organizers of the most significant ones. The mentioned marketing research involves: research of the local market, visitors satisfaction research, evaluation of sponsorship effectiveness, research of the sport events economic influence on the local community or host cities, event host attitudes examination-local population and so on. The marketing research process, for the sport event organizers of needs, involves several steps, such as: goal definition, choice of the research method, research instruments determination, interviewer education, information gathering, data processing, data report, conclusions.

Local adaptations to a global health initiative: penalties for home births in Zambia.

Science.gov (United States)

Greeson, Dana; Sacks, Emma; Masvawure, Tsitsi B; Austin-Evelyn, Katherine; Kruk, Margaret E; Macwan'gi, Mubiana; Grépin, Karen A

2016-11-01

Global health initiatives (GHIs) are implemented across a variety of geographies and cultures. Those targeting maternal health often prioritise increasing facility delivery rates. Pressure on local implementers to meet GHI goals may lead to unintended programme features that could negatively impact women. This study investigates penalties for home births imposed by traditional leaders on women during the implementation of Saving Mothers, Giving Life (SMGL) in Zambia. Forty focus group discussions (FGDs) were conducted across four rural districts to assess community experiences of SMGL at the conclusion of its first year. Participants included women who recently delivered at home (3 FGDs/district), women who recently delivered in a health facility (3 FGDs/district), community health workers (2 FGDs/district) and local leaders (2 FGDs/district). Findings indicate that community leaders in some districts-independently of formal programme directive-used fines to penalise women who delivered at home rather than in a facility. Participants in nearly all focus groups reported hearing about the imposition of penalties following programme implementation. Some women reported experiencing penalties firsthand, including cash and livestock fines, or fees for child health cards that are typically free. Many women who delivered at home reported their intention to deliver in a facility in the future to avoid penalties. While communities largely supported the use of penalties to promote facility delivery, the penalties effectively introduced a new tax on poor rural women and may have deterred their utilization of postnatal and child health care services. The imposition of penalties is thus a punitive adaptation that can impose new financial burdens on vulnerable women and contribute to widening health, economic and gender inequities in communities. Health initiatives that aim to increase demand for health services should monitor local efforts to achieve programme targets in order

The dynamic relationship between current and previous severe hypoglycemic events: a lagged dependent variable analysis among patients with type 2 diabetes who have initiated basal insulin.

Science.gov (United States)

Ganz, Michael L; Li, Qian; Wintfeld, Neil S; Lee, Yuan-Chi; Sorli, Christopher; Huang, Joanna C

2015-01-01

Past studies have found episodes of severe hypoglycemia (SH) to be serially dependent. Those studies, however, only considered the impact of a single (index) event on future risk; few have analyzed SH risk as it evolves over time in the presence (or absence) of continuing events. The objective of this study was to determine the dynamic risks of SH events conditional on preceding SH events among patients with type 2 diabetes (T2D) who have initiated basal insulin. We used an electronic health records database from the United States that included encounter and laboratory data and clinical notes on T2D patients who initiated basal insulin therapy between 2008 and 2011 and to identify SH events. We used a repeated-measures lagged dependent variable logistic regression model to estimate the impact of SH in one quarter on the risk of SH in the next quarter. We identified 7235 patients with T2D who initiated basal insulin. Patients who experienced ≥1 SH event during any quarter were more likely to have ≥1 SH event during the subsequent quarter than those who did not (predicted probabilities of 7.4% and 1.0%, respectively; p history of SH before starting basal insulin (predicted probabilities of 1.0% and 3.2%, respectively; p history of SH during the titration period (predicted probabilities of 1.1% and 2.8%, respectively; p history of SH events and therefore the value of preventing one SH event may be substantial. These results can inform patient care by providing clinicians with dynamic data on a patient's risk of SH, which in turn can facilitate appropriate adjustment of the risk-benefit ratio for individualized patient care. These results should, however, be interpreted in light of the key limitations of our study: not all SH events may have been captured or coded in the database, data on filled prescriptions were not available, we were unable to adjust for basal insulin dose, and the post-titration follow-up period could have divided into time units other

76 FR 38077 - Special Local Regulations and Safety Zones; Recurring Events in Captain of the Port New York Zone

Science.gov (United States)

2011-06-29

...: All Zone. waters of Long Island Sound in an area bound by the following points: 40[deg]51'43.5'' N 073... Zone. located in approximate position 40[deg]51'52'' N 073[deg]56'24'' W (NAD 1983), approximately 1750...] RIN 1625-AA00; 1625-AA08 Special Local Regulations and Safety Zones; Recurring Events in Captain of...

Charge-dependent correlations from event-by-event anomalous hydrodynamics

Energy Technology Data Exchange (ETDEWEB)

Hirono, Yuji [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794-3800 (United States); Hirano, Tetsufumi [Department of Physics, Sophia University, Tokyo 102-8554 (Japan); Kharzeev, Dmitri E. [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794-3800 (United States); Department of Physics and RIKEN-BNL Research Center, Brookhaven National Laboratory, Upton, NY 11973-5000 (United States)

2016-12-15

We report on our recent attempt of quantitative modeling of the Chiral Magnetic Effect (CME) in heavy-ion collisions. We perform 3+1 dimensional anomalous hydrodynamic simulations on an event-by-event basis, with constitutive equations that contain the anomaly-induced effects. We also develop a model of the initial condition for the axial charge density that captures the statistical nature of random chirality imbalances created by the color flux tubes. Basing on the event-by-event hydrodynamic simulations for hundreds of thousands of collisions, we calculate the correlation functions that are measured in experiments, and discuss how the anomalous transport affects these observables.

Evaluation of local stress for stress corrosion crack initiation by three-dimensional polycrystal model

International Nuclear Information System (INIS)

Kamaya, Masayuki; Kitamura, Takayuki

2006-01-01

In order to understand the initiation behavior of microstructurally small cracks in a stress corrosion cracking condition, it is important to know the tensile normal stress acting on the grain boundary (normal G.B. stress). The local stress in a polycrystalline body is greatly influenced by deformation constraint which is caused by anisotropic and/or inhomogeneous property of each grain. In present study, the local normal G.B. stress on bi- and tri-crystal bodies and a three-dimensional polycrystalline body consisting of 100 grains were evaluated by the finite element method under a remote uniform tensile stress condition. The polycrystalline body was generated by using a Monte Carlo procedure and random orientations were assigned to each grain. It was revealed that the local normal G.B. stress on the polycrystalline body is inhomogeneous under uniform applied stress. The stress tends to be large near the triple points due to the deformation constraint caused by adjacent grains, even though the grain boundary inclination to the load axis has large influence. It was also shown that particular high stress was not observed at corners of the polycrystalline body. (author)

Enhancement of thermal photon production in event-by-event hydrodynamics

International Nuclear Information System (INIS)

Chatterjee, Rupa; Holopainen, Hannu; Renk, Thorsten; Eskola, Kari J.

2011-01-01

Thermal photon emission is widely believed to reflect properties of the earliest, hottest evolution stage of the medium created in ultrarelativistic heavy-ion collisions. Previous computations of photon emission have been carried out using a hydrodynamical medium description with smooth, averaged initial conditions. Recently, more sophisticated hydrodynamical models that calculate observables by averaging over many evolutions with event-by-event fluctuating initial conditions (ICs) have been developed. Given their direct connection to the early time dynamics, thermal photon emission appears to be an ideal observable to probe fluctuations in the medium initial state. In this work, we demonstrate that including fluctuations in the ICs may lead to an enhancement of the thermal photon yield of about a factor of 2 in the region 2 T <4 GeV/c (where thermal photon production dominates the direct photon yield) compared to a scenario using smooth, averaged ICs. Consequently, a much better agreement with PHENIX data is found. This can be understood in terms of the strong temperature dependence of thermal photon production, translating into a sensitivity to the presence of hotspots in an event and thus establishing thermal photons as a suitable probe to characterize IC fluctuations.

Strain localization and fatigue crack initiation in ultrafine-grained copper in high- and giga-cycle region

Czech Academy of Sciences Publication Activity Database

Kunz, Ludvík; Lukáš, Petr; Navrátilová, L.

2014-01-01

Roč. 58, JAN (2014), s. 202-208 ISSN 0142-1123 R&D Projects: GA ČR GAP108/10/2001; GA MŠk(CZ) ED1.1.00/02.0068 Institutional support: RVO:68081723 Keywords : Fatigue crack initiation * Strain localization * Stability of ultrafine-grained structure * UFG Cu Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 2.275, year: 2014

Coupled prediction of flood response and debris flow initiation during warm and cold season events in the Southern Appalachians, USA

Science.gov (United States)

Tao, J.; Barros, A. P.

2013-07-01

Debris flows associated with rainstorms are a frequent and devastating hazard in the Southern Appalachians in the United States. Whereas warm season events are clearly associated with heavy rainfall intensity, the same cannot be said for the cold season events. Instead, there is a relationship between large (cumulative) rainfall events independently of season, and thus hydrometeorological regime, and debris flows. This suggests that the dynamics of subsurface hydrologic processes play an important role as a trigger mechanism, specifically through soil moisture redistribution by interflow. The first objective of this study is to investigate this hypothesis. The second objective is to assess the physical basis for a regional coupled flood prediction and debris flow warning system. For this purpose, uncalibrated model simulations of well-documented debris flows in headwater catchments of the Southern Appalachians using a 3-D surface-groundwater hydrologic model coupled with slope stability models are examined in detail. Specifically, we focus on two vulnerable headwater catchments that experience frequent debris flows, the Big Creek and the Jonathan Creek in the Upper Pigeon River Basin, North Carolina, and three distinct weather systems: an extremely heavy summertime convective storm in 2011; a persistent winter storm lasting several days; and a severe winter storm in 2009. These events were selected due to the optimal availability of rainfall observations, availability of detailed field surveys of the landslides shortly after they occurred, which can be used to evaluate model predictions, and because they are representative of events that cause major economic losses in the region. The model results substantiate that interflow is a useful prognostic of conditions necessary for the initiation of slope instability, and should therefore be considered explicitly in landslide hazard assessments. Moreover, the relationships between slope stability and interflow are

A study of the state of the art on the determination of the threshold values of the performance indicators for safety systems and initiating events of nuclear power plants

Energy Technology Data Exchange (ETDEWEB)

Kang, D. I.; Kim, K. Y.; Hwang, M. J.; Park, J. H.; Ha, J. J

2004-02-01

The threshold values of Korean Institute of Nuclear Safety (KINS) Performance Indicators (PIs)' determining the safety class of initiating events and safety systems can not sufficiently reflect the operating experience and PSA results of domestic NPPs. Therefore, the state of arts on the PI study of domestic and foreign countries is analyzed in order to reflect the operating experience and PSA results of domestic NPPs in the determination of the threshold values of the PIs for safety systems and initiating events of domestic NPPs. We identified the state of arts of PIs through reviewing the objectives and types of WANO, IAEA, NRC, OECD/NEA and domestic PIs, and the technical issues of the threshold values of SECY 99-007 and NUREG-1753. We also, identified the current status of recently developed MSPI (Mitigating System Performance Index) and IIIEI (Integrated Industry Initiating Event Indicator). From this study of the state of the arts on the PIs, we expect that if the NRC's MSPI and a PI similar to NRC's IIIEI would be introduced into the KINS, it is not necessary to determine the threshold values of PIs applied to the safety systems and initiating events of entire domestic NPPs. Otherwise the threshold values of PIs applied to the individual NPP should be developed using PSA models of typical reactor types. For the active development and use of the risk informed PIs for the domestic NPPs, we expect that the system and component reliability analysis and initiating events analysis for the domestic NPPs, MSPI, IIIEI, and PSA requirements for the PIs be further studied.

Early Glycemic Control and Magnitude of HbA1c Reduction Predict Cardiovascular Events and Mortality: Population-Based Cohort Study of 24,752 Metformin Initiators.

Science.gov (United States)

Svensson, Elisabeth; Baggesen, Lisbeth M; Johnsen, Søren P; Pedersen, Lars; Nørrelund, Helene; Buhl, Esben S; Haase, Christiane L; Thomsen, Reimar W

2017-06-01

We investigated the association of early achieved HbA 1c level and magnitude of HbA 1c reduction with subsequent risk of cardiovascular events or death in patients with type 2 diabetes who initiate metformin. This was a population-based cohort study including all metformin initiators with HbA 1c tests in Northern Denmark, 2000-2012. Six months after metformin initiation, we classified patients by HbA 1c achieved (<6.5% or higher) and by magnitude of HbA 1c change from the pretreatment baseline. We used Cox regression to examine subsequent rates of acute myocardial infarction, stroke, or death, controlling for baseline HbA 1c and other confounding factors. We included 24,752 metformin initiators (median age 62.5 years, 55% males) with a median follow-up of 2.6 years. The risk of a combined outcome event gradually increased with rising levels of HbA 1c achieved compared with a target HbA 1c of <6.5%: adjusted hazard ratio (HR) 1.18 (95% CI 1.07-1.30) for 6.5-6.99%, HR 1.23 (1.09-1.40) for 7.0-7.49%, HR 1.34 (1.14-1.57) for 7.5-7.99%, and HR 1.59 (1.37-1.84) for ≥8%. Results were consistent for individual outcome events and robust by age-group and other patient characteristics. A large absolute HbA 1c reduction from baseline also predicted outcome: adjusted HR 0.80 (0.65-0.97) for Δ = -4, HR 0.98 (0.80-1.20) for Δ = -3, HR 0.92 (0.78-1.08) for Δ = -2, and HR 0.99 (0.89-1.10) for Δ = -1 compared with no HbA 1c change (Δ = 0). A large initial HbA 1c reduction and achievement of low HbA 1c levels within 6 months after metformin initiation are associated with a lower risk of cardiovascular events and death in patients with type 2 diabetes. © 2017 by the American Diabetes Association.

Production of meat of rabbit, an alternative for the cooperative sector palmero to inclination of a project of municipal initiative of local development

Directory of Open Access Journals (Sweden)

Raúl Rosales Guzmán

2015-06-01

Full Text Available The present article contains an analysis on the possibilities offered by the cooperative sector in La Palma, which is supported by the local development initiative of breeding rabbits. This activity can be easily carried out with minimal cost and effort, and is supported by a tradition in the local population, mainly in the private sector. The proposal will allow the production of rabbit meat in order to ease the difficult situation regarding meat supply; constitute the fundamental problem of how to incorporate research conducted the cooperative sector in La Palma to development projects municipal initiative? The Group of Local Development in La Palma has a project portfolio in which many important enterprises take part, with lack of initiation on the cooperative sector, which is basic for La Palma’s and Cuba’s economy. This proposal is also sustained by the fact that all cooperatives in that territory have a great deal of resources of all kinds (human, natural, etc which will allow for a sustainable development and the improvement of life quality standards for associates and inhabitants in general.  The aim of the research conducted to analyze the possibilities of the cooperative sector in the municipality of La Palma, incorporating the process of local development initiative, through a project on breeding rabbit and improve the supply of meat in the town

Event classification related to overflow of solvent containing uranium according to the INES scale (International Nuclear and Radiological Event Scale); Classificacao do evento de transbordamento de solvente contendo uranio segundo a escala INES (International Nuclear and Radiological Event Scale)

Energy Technology Data Exchange (ETDEWEB)

Dourado, Eneida R.G.; Assis, Juliana T. de; Lage, Ricardo F., E-mail: cneida@inb.gov.br, E-mail: julianateixeira@inb.gov.br, E-mail: rlage@inb.gov.br [lndustrias Nucleares do Brasil S/A (CLISE.P/INB), Rio de Janeiro, RJ (Brazil). Coordenacao de Licenciamento Nuclear e Ambiental, Saude e Seguranca; Lopes, Karina B., E-mail: karina@inb.gov.br [lndustrias Nucleares do Brasil S/A (CPRAD/INB), Rio de Janeiro, RJ (Brazil). Coordenacao de Protecao Radiologica

2013-11-01

This paper aims to frame the event overflow organic solvent rich in uranium, from a decanter of ore beneficiation plant, caused by the fall in the supply of electricity, according to the criteria established by the International Nuclear Event Scale and radiological (INES), facilitating the understanding of the occurrence and communication with the public regarding the radiation safety aspects involved. With the fall of electricity, routine procedures in situations of installation stop were performed, however, due to operational failure, the valve on the transfer line liquor was not closed. Thus, the mixer continued being fed with liquor, that led the consequent leakage of solvent loaded with uranium. It reached the drainage system, and the box of rainwater harvesting of the plant. However, immediately after the detection of the event, corrective actions were initiated and the overflow was contained. Regulatory agencies followed the removal of the solvent and on the results of the analysis of environmental monitoring, found that the event did not provide exposure to workers or any other impact. Therefore, comparing the characteristics of the event and the guidelines proposed by the INES scale, it is concluded that the classification of the event is below scale/level 0, confirming the absence of risk to the local population, workers and the environment.

A Method to Quantify Plant Availability and Initiating Event Frequency Using a Large Event Tree, Small Fault Tree Model

International Nuclear Information System (INIS)

Kee, Ernest J.; Sun, Alice; Rodgers, Shawn; Popova, ElmiraV; Nelson, Paul; Moiseytseva, Vera; Wang, Eric

2006-01-01

South Texas Project uses a large fault tree to produce scenarios (minimal cut sets) used in quantification of plant availability and event frequency predictions. On the other hand, the South Texas Project probabilistic risk assessment model uses a large event tree, small fault tree for quantifying core damage and radioactive release frequency predictions. The South Texas Project is converting its availability and event frequency model to use a large event tree, small fault in an effort to streamline application support and to provide additional detail in results. The availability and event frequency model as well as the applications it supports (maintenance and operational risk management, system engineering health assessment, preventive maintenance optimization, and RIAM) are briefly described. A methodology to perform availability modeling in a large event tree, small fault tree framework is described in detail. How the methodology can be used to support South Texas Project maintenance and operations risk management is described in detail. Differences with other fault tree methods and other recently proposed methods are discussed in detail. While the methods described are novel to the South Texas Project Risk Management program and to large event tree, small fault tree models, concepts in the area of application support and availability modeling have wider applicability to the industry. (authors)

Local recurrences and distant metastases after breast-conservative treatments in a population at very low risk of recurrence are very dependent events

International Nuclear Information System (INIS)

Cowen, Didier; Jacquemier, Jocelyne; Houvenaeghel, Gilles; Viens, Patrice; Maraninchi, Dominique; Puig, Brigitte; Bardou, Valerie-Jeanne; Resbeut, Michel

1997-01-01

HM (p=0.0016), PVI (p=0.0093), age ≤ 40yrs (p=0.015), and grade III disease (p=0.046) had more LRFs. In the multivariate analysis HM (p=0.0076), PVI (p=0.021) and age ≤ 40yrs (p=0.024) were independent prognostic factors of LRF. Five and ten-year freedom from M was 67% and 44.6% respectively, for patients who had a local recurrence. Patients with a tumor size >20 mm (p=0.0013), aged ≤ 40yrs (p=0.0019), and HM (p=0.0195), had more M. In the multivariate analysis a tumor size >20 mm (p=0.0013), age ≤ 40 yrs (p=0.003), and HM (p=0.041) were independent prognostic factors of distant failure. CONCLUSION: In this > population, LRF and M shared similar prognostic factors and had equal yearly probabilities of occurence. The frequency of M in patients who had a local recurrence showed a fourfold increase when compared with patients who had no such event. We conclude that in this subset of patients local recurrence is evidence of tumor aggressiveness. We have identified a high-risk subgroup which could benefit of a more aggressive initial treatment

Identification and localization of neutrino events in the OPERA detector; Identification et localisation des evenements neutrino dans le detecteur OPERA

Energy Technology Data Exchange (ETDEWEB)

Heritier, C

2004-07-15

The OPERA experiment is designed for the appearance search of {nu}{sub {mu}} {yields} {nu}{sub {tau}} oscillations in the parameters indicated by the atmospheric neutrino anomaly. To prove the appearance of {nu}{sub {tau}} at 732 km from the CERN, an hybrid detector is under construction at the Gran Sasso laboratory. The target, composed by bricks made of lead plates and emulsion sheets, allows the direct observation of the {tau} lepton produced in {nu}{sub {tau}} charged current interactions. The tracking, the localization of neutrino events in the target and the muon identification are allowed by trackers located inside the target (scintillators) and in the spectrometer following the target (RPC). The development of algorithms, based on electronic detectors, is necessary to identify the neutrino interaction and to locate the bricks where the interaction occurred. A classification of neutrino events is performed using the identification of the muon produced in {nu}{sub {mu}} CC and {nu}{sub {tau}} CC with {tau} {yields} {mu} decay. This classification is optimised with tracking informations and also with topological and calorimetric parameters which describe the nature of the interaction (quasi-elastic, deep inelastic); the algorithm of the localization of neutrino event is performed for each category. A tridimensional brick probability map is built and can be exploited to implement sophisticated extraction brick strategies. To conclude, a feasibility study of a test beam experiment OPERETTE is presented. The project was to install a similar OPERA detector in the COMPASS neutrino beam, in the CERN North Area. It was a good opportunity to prepare OPERA for the scanning emulsion films with neutrino events and to test the analysis procedures. (author)

Probabilistic analysis of external events with focus on the Fukushima event

International Nuclear Information System (INIS)

Kollasko, Heiko; Jockenhoevel-Barttfeld, Mariana; Klapp, Ulrich

2014-01-01

External hazards are those natural or man-made hazards to a site and facilities that are originated externally to both the site and its processes, i.e. the duty holder may have very little or no control over the hazard. External hazards can have the potential of causing initiating events at the plant, typically transients like e.g., loss of offsite power. Simultaneously, external events may affect safety systems required to control the initiating event and, where applicable, also back-up systems implemented for risk-reduction. The plant safety may especially be threatened when loads from external hazards exceed the load assumptions considered in the design of safety-related systems, structures and components. Another potential threat is given by hazards inducing initiating events not considered in the safety demonstration otherwise. An example is loss of offsite power combined with prolonged plant isolation. Offsite support, e.g., delivery of diesel fuel oil, usually credited in the deterministic safety analysis may not be possible in this case. As the Fukushima events have shown, the biggest threat is likely given by hazards inducing both effects. Such hazards may well be dominant risk contributors even if their return period is very high. In order to identify relevant external hazards for a certain Nuclear Power Plant (NPP) location, a site specific screening analysis is performed, both for single events and for combinations of external events. As a result of the screening analysis, risk significant and therefore relevant (screened-in) single external events and combinations of them are identified for a site. The screened-in events are further considered in a detailed event tree analysis in the frame of the Probabilistic Safety Analysis (PSA) to calculate the core damage/large release frequency resulting from each relevant external event or from each relevant combination. Screening analyses of external events performed at AREVA are based on the approach provided

Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail

Directory of Open Access Journals (Sweden)

Burghardt Bernd

2007-07-01

Full Text Available Abstract Background The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the important case, where gaps are allowed. For this case, the distribution is only known empirically in the high-probability region, which is biologically less relevant. Results We provide a method to obtain numerically the biologically relevant rare-event tail of the distribution. The method, which has been outlined in an earlier work, is based on generating the sequences with a parametrized probability distribution, which is biased with respect to the original biological one, in the framework of Metropolis Coupled Markov Chain Monte Carlo. Here, we first present the approach in detail and evaluate the convergence of the algorithm by considering a simple test case. In the earlier work, the method was just applied to one single example case. Therefore, we consider here a large set of parameters: We study the distributions for protein alignment with different substitution matrices (BLOSUM62 and PAM250 and affine gap costs with different parameter values. In the logarithmic phase (large gap costs it was previously assumed that the Gumbel form still holds, hence the Gumbel distribution is usually used when evaluating p-values in databases. Here we show that for all cases, provided that the sequences are not too long (L > 400, a "modified" Gumbel distribution, i.e. a Gumbel distribution with an additional Gaussian factor is suitable to describe the data. We also provide a "scaling analysis" of the parameters used in the modified Gumbel distribution. Furthermore, via a comparison with BLAST parameters, we show that significance estimations change considerably when using the true distributions as presented here. Finally, we study also the distribution of the sum statistics of the k best alignments. Conclusion Our results show that the statistics of gapped and ungapped local

Fungal Iron Availability during Deep Seated Candidiasis Is Defined by a Complex Interplay Involving Systemic and Local Events

Science.gov (United States)

Potrykus, Joanna; Stead, David; MacCallum, Donna M.; Urgast, Dagmar S.; Raab, Andrea; van Rooijen, Nico; Feldmann, Jörg; Brown, Alistair J. P.

2013-01-01

Nutritional immunity – the withholding of nutrients by the host – has long been recognised as an important factor that shapes bacterial-host interactions. However, the dynamics of nutrient availability within local host niches during fungal infection are poorly defined. We have combined laser ablation-inductively coupled plasma mass spectrometry (LA-ICP MS), MALDI imaging and immunohistochemistry with microtranscriptomics to examine iron homeostasis in the host and pathogen in the murine model of systemic candidiasis. Dramatic changes in the renal iron landscape occur during disease progression. The infection perturbs global iron homeostasis in the host leading to iron accumulation in the renal medulla. Paradoxically, this is accompanied by nutritional immunity in the renal cortex as iron exclusion zones emerge locally around fungal lesions. These exclusion zones correlate with immune infiltrates and haem oxygenase 1-expressing host cells. This local nutritional immunity decreases iron availability, leading to a switch in iron acquisition mechanisms within mature fungal lesions, as revealed by laser capture microdissection and qRT-PCR analyses. Therefore, a complex interplay of systemic and local events influences iron homeostasis and pathogen-host dynamics during disease progression. PMID:24146619

Impact of sport events on local communities : dimensions and measures

NARCIS (Netherlands)

Slender, Hans; Straatmeijer, Jerzy; Hover, Paul; Cevaal, Astrid

2015-01-01

Abstract for the European Association of Sociology for Sport conference in Dublin on the development over time of social impact evaluations in the Netherlands. In total 33 sport events were included that were held between 1980-2015 in the Netherlands. The events were selected to vary in fixed vs.

Elevated Immune Response Among Children 4 Years of Age With Pronounced Local Adverse Events After the Fifth Diphtheria, Tetanus, Acellular Pertussis Vaccination.

NARCIS (Netherlands)

van der Lee, Saskia; Kemmeren, Jeanet M; de Rond, Lia G H; Öztürk, Kemal; Westerhof, Anneke; de Melker, Hester E; Sanders, Elisabeth A M; Berbers, Guy A M; van der Maas, Nicoline A T; Rümke, Hans C; Buisman, Anne-Marie

In the Netherlands, acellular pertussis vaccines replaced the more reactogenic whole-cell pertussis vaccines. This replacement in the primary immunization schedule of infants coincided with a significant increase in pronounced local adverse events (AEs) in 4 years old children shortly after the

Clinical outcomes of radiotherapy as initial local therapy for Graves’ ophthalmopathy and predictors of the need for post-radiotherapy decompressive surgery

International Nuclear Information System (INIS)

Prabhu, Roshan S; Liebman, Lang; Wojno, Ted; Hayek, Brent; Hall, William A; Crocker, Ian

2012-01-01

The optimal initial local treatment for patients with Graves’ ophthalmopathy (GO) is not fully characterized. The purpose of this retrospective study is to describe the clinical outcomes of RT as initial local therapy for GO and define predictors of the need for post-RT salvage bony decompressive surgery. 91 patients with active GO and without prior surgery were treated with RT as initial local therapy between 01/1999 and 12/2010, with a median follow-up period of 18.3 months (range 3.7 - 142 months). RT dose was 24 Gy in 12 fractions. 44 patients (48.4%) had prior use of steroids, with 31 (34.1%) being on steroids at the initiation of RT. The most common presenting symptoms were diplopia (79%), proptosis (71%) and soft tissue signs (62%). 84 patients (92.3%) experienced stabilization or improvement of GO symptoms. 58 patients (64%) experienced improvement in their symptoms. 19 patients (20.9%) underwent salvage post-RT bony decompressive surgery. Smoking status and total symptom score at 4 months were independent predictors of post-RT bony decompression with odds ratios of 3.23 (95% CI 1.03 – 10.2) and 1.59 (95% CI 1.06 – 2.4), respectively. Persistent objective vision loss at 4 months post-RT was the most important symptom type in predicting salvage decompression. Chronic dry eye occurred in 9 patients (9.9%) and cataracts developed in 4 patients (4.4%). RT is effective and well tolerated as initial local therapy for active GO, with only 21% of patients requiring decompressive surgery post RT. Most patients experience stabilization or improvement of GO symptoms, but moderate to significant response occurs in the minority of patients. Smoking status and total symptom severity at 4 months, primarily persistent objective vision loss, are the primary determinants of the need for post-RT salvage bony decompression. Patients who smoke or present with predominantly vision loss symptoms should be advised as to their lower likelihood of symptomatic response to RT

Hospital staff should use more than one method to detect adverse events and potential adverse events: incident reporting, pharmacist surveillance and local real‐time record review may all have a place

Science.gov (United States)

Olsen, Sisse; Neale, Graham; Schwab, Kat; Psaila, Beth; Patel, Tejal; Chapman, E Jane; Vincent, Charles

2007-01-01

Background Over the past five years, in most hospitals in England and Wales, incident reporting has become well established but it remains unclear how well reports match clinical adverse events. International epidemiological studies of adverse events are based on retrospective, multi‐hospital case record review. In this paper the authors describe the use of incident reporting, pharmacist surveillance and local real‐time record review for the recognition of clinical risks associated with hospital inpatient care. Methodology Data on adverse events were collected prospectively on 288 patients discharged from adult acute medical and surgical units in an NHS district general hospital using incident reports, active surveillance of prescription charts by pharmacists and record review at time of discharge. Results Record review detected 26 adverse events (AEs) and 40 potential adverse events (PAEs) occurring during the index admission. In contrast, in the same patient group, incident reporting detected 11 PAEs and no AEs. Pharmacy surveillance found 10 medication errors all of which were PAEs. There was little overlap in the nature of events detected by the three methods. Conclusion The findings suggest that incident reporting does not provide an adequate assessment of clinical adverse events and that this method needs to be supplemented with other more systematic forms of data collection. Structured record review, carried out by clinicians, provides an important component of an integrated approach to identifying risk in the context of developing a safety and quality improvement programme. PMID:17301203

A detector for localizing diverging beams of ionizing radiations

International Nuclear Information System (INIS)

Allemand, Robert.

1974-01-01

Description is given of a detector for localizing diverging radiation beams, adapted to provide the angular distribution of nuclear events. That detector comprises a casing filled with a fluid adapted to produce electric charges under radiations and provided with a front-side and a rear-side, means for generating an electric field at right angles to portions of parallel surfaces of revolution having in common an axis of revolution contained in the place of symmetry, and a plane unit for localizing electric charges mounted at the rear of said means, the initial portion of the beam being on the axis of revolution. This can be applied to X-ray diffraction and to neutron diffraction [fr

Survey on Prognostics Techniques for Updating Initiating Event Frequency in PSA

International Nuclear Information System (INIS)

Kim, Hyeonmin; Heo, Gyunyoung

2015-01-01

One of the applications using PSA is a risk monito. The risk monitoring is real-time analysis tool to decide real-time risk based on real state of components and systems. In order to utilize more effective, the methodologies that manipulate the data from Prognostics was suggested. Generally, Prognostic comprehensively includes not only prognostic but also monitoring and diagnostic. The prognostic method must need condition monitoring. In case of applying PHM to a PSA model, the latest condition of NPPs can be identified more clearly. For reducing the conservatism and uncertainties, we suggested the concept that updates the initiating event frequency in a PSA model by using Bayesian approach which is one of the prognostics techniques before. From previous research, the possibility that PSA is updated by using data more correctly was found. In reliability theory, the Bathtub curve divides three parts (infant failure, constant and random failure, wareout failure). In this paper, in order to investigate the applicability of prognostic methods in updating quantitative data in a PSA model, the OLM acceptance criteria from NUREG, the concept of how to using prognostic in PSA, and the enabling prognostic techniques are suggested. The prognostic has the motivation that improved the predictive capabilities using existing monitoring systems, data, and information will enable more accurate equipment risk assessment for improved decision-making

Survey on Prognostics Techniques for Updating Initiating Event Frequency in PSA

Energy Technology Data Exchange (ETDEWEB)

Kim, Hyeonmin; Heo, Gyunyoung [Kyung Hee University, Yongin (Korea, Republic of)

2015-05-15

One of the applications using PSA is a risk monito. The risk monitoring is real-time analysis tool to decide real-time risk based on real state of components and systems. In order to utilize more effective, the methodologies that manipulate the data from Prognostics was suggested. Generally, Prognostic comprehensively includes not only prognostic but also monitoring and diagnostic. The prognostic method must need condition monitoring. In case of applying PHM to a PSA model, the latest condition of NPPs can be identified more clearly. For reducing the conservatism and uncertainties, we suggested the concept that updates the initiating event frequency in a PSA model by using Bayesian approach which is one of the prognostics techniques before. From previous research, the possibility that PSA is updated by using data more correctly was found. In reliability theory, the Bathtub curve divides three parts (infant failure, constant and random failure, wareout failure). In this paper, in order to investigate the applicability of prognostic methods in updating quantitative data in a PSA model, the OLM acceptance criteria from NUREG, the concept of how to using prognostic in PSA, and the enabling prognostic techniques are suggested. The prognostic has the motivation that improved the predictive capabilities using existing monitoring systems, data, and information will enable more accurate equipment risk assessment for improved decision-making.

Effect of initiation-inhibition and handedness on the patterns of the P50 event-related potential component: a low resolution electromagnetic tomography study

Directory of Open Access Journals (Sweden)

Capsalis Christos N

2009-12-01

Full Text Available Abstract Background Recent research recognizes the association between handedness, linguistic processes and cerebral networks subserving executive functioning, but the nature of this association remains unclear. Since the P50 event related potential (ERP is considered to reflect thalamocortical processes in association with working memory (WM operation the present study focuses on P50 patterns elicited during the performance of a linguistic related executive functioning test in right- and left-handers. Methods In 64 young adults with a high educational level (33 left-handed the P50 event-related potential was recorded while performing the initiation and inhibition condition of a modified version of the Hayling Sentence Completion test adjusted to induce WM. The manual preference of the participants was evaluated with the use of the Edinburgh Handedness Inventory (EHI. Results P50 showed greater amplitudes in left- than in right-handers, mainly in frontal leads, in the initiation condition. Reduced amplitudes in inhibition compared to initiation condition were observed in left-handers. Low Resolution Electromagnetic Tomography (LORETA analysis showed lower frontal lobe activation in the inhibition than in the initiation condition in both right- and left-handers. Also, LORETA yielded that right-handers exhibited greater activation in the inhibition condition than left-handers. Additionally, LORETA showed assymetrical hemispheric activation patterns in right-handers, in contrast to symmetrical patterns observed in left-handers. Higher P50 amplitudes were recorded in right-hemisphere of right-handers in the initiation condition. Conclusion Brain activation, especially the one closely related to thalamocortical function, elicited during WM operation involving initiation and inhibition processes appears to be related to handedness.

Simulation of surface crack initiation induced by slip localization and point defects kinetics

International Nuclear Information System (INIS)

Sauzay, Maxime; Liu, Jia; Rachdi, Fatima

2014-01-01

Crack initiation along surface persistent slip bands (PSBs) has been widely observed and modelled. Nevertheless, from our knowledge, no physically-based fracture modelling has been proposed and validated with respect to the numerous recent experimental data showing the strong relationship between extrusion and microcrack initiation. The whole FE modelling accounts for: - localized plastic slip in PSBs; - production and annihilation of vacancies induced by cyclic slip. If temperature is high enough, point defects may diffuse in the surrounding matrix due to large concentration gradients, allowing continuous extrusion growth in agreement with Polak's model. At each cycle, the additional atoms diffusing from the matrix are taken into account by imposing an incremental free dilatation; - brittle fracture at the interfaces between PSBs and their surrounding matrix which is simulated using cohesive zone modelling. Any inverse fitting of parameter is avoided. Only experimental single crystal data are used such as hysteresis loops and resistivity values. Two fracture parameters are required: the {111} surface energy which depends on environment and the cleavage stress which is predicted by the universal binding energy relationship. The predicted extrusion growth curves agree rather well with the experimental data published for copper and the 316L steel. A linear dependence with respect to PSB length, thickness and slip plane angle is predicted in agreement with recent AFM measurement results. Crack initiation simulations predict fairly well the effects of PSB length and environment for copper single and poly-crystals. (authors)

Corporate Policy Conferences and Events

International Development Research Centre (IDRC) Digital Library (Canada)

André Lavoie

2015-10-15

Oct 15, 2015 ... Hospitality as defined in the Corporate Hospitality Policy; ... awards and recognition ceremonies; social events and any other ... The Convenor is the person who initiates an event and takes responsibility for its conduct.

Improvement of Early Antenatal Care Initiation: The Effects of Training Local Health Volunteers in the Community.

Science.gov (United States)

Liabsuetrakul, Tippawan; Oumudee, Nurlisa; Armeeroh, Masuenah; Nima, Niamina; Duerahing, Nurosanah

2018-01-01

Although antenatal care (ANC) coverage has been increasing in low- and middle-income countries, the adherence to the ANC initiation standards at gestational age ANC initiation by training the existing local health volunteers (LHVs) in 3 southernmost provinces of Thailand. A clustered nonrandomized intervention study was conducted from November 2012 to February 2014. One district of each province was selected to be the study intervention districts for that province. A total of 124 LHVs in the intervention districts participated in the knowledge-counseling intervention. It was organized as half-day workshop using 2 training modules each comprising a 30-minute lecture followed by counseling practice in pairs for 1 hour. Outcome was the rate of early ANC initiation among women giving birth, and its association with intervention, meeting an LHV, and months after training was analyzed. Of 6677 women, 3178 and 3499 women were in the control and intervention groups, respectively. Rates of early ANC were significantly improved after the intervention (adjusted odds ratio [OR]: 1.29, 95% confidence interval [CI]: 1.17-1.43, P ANC. Training LHVs in communities by knowledge-counseling intervention significantly improved early ANC initiation, but the magnitude of change was still limited.

Extreme Events in China under Climate Change: Uncertainty and related impacts (CSSP-FOREX)

Science.gov (United States)

Leckebusch, Gregor C.; Befort, Daniel J.; Hodges, Kevin I.

2016-04-01

Suitable adaptation strategies or the timely initiation of related mitigation efforts in East Asia will strongly depend on robust and comprehensive information about future near-term as well as long-term potential changes in the climate system. Therefore, understanding the driving mechanisms associated with the East Asian climate is of major importance. The FOREX project (Fostering Regional Decision Making by the Assessment of Uncertainties of Future Regional Extremes and their Linkage to Global Climate System Variability for China and East Asia) focuses on the investigation of extreme wind and rainfall related events over Eastern Asia and their possible future changes. Here, analyses focus on the link between local extreme events and their driving weather systems. This includes the coupling between local rainfall extremes and tropical cyclones, the Meiyu frontal system, extra-tropical teleconnections and monsoonal activity. Furthermore, the relation between these driving weather systems and large-scale variability modes, e.g. NAO, PDO, ENSO is analysed. Thus, beside analysing future changes of local extreme events, the temporal variability of their driving weather systems and related large-scale variability modes will be assessed in current CMIP5 global model simulations to obtain more robust results. Beyond an overview of FOREX itself, first results regarding the link between local extremes and their steering weather systems based on observational and reanalysis data are shown. Special focus is laid on the contribution of monsoonal activity, tropical cyclones and the Meiyu frontal system on the inter-annual variability of the East Asian summer rainfall.

Local-scale analysis of temperature patterns over Poland during heatwave events

Science.gov (United States)

Krzyżewska, Agnieszka; Dyer, Jamie

2018-01-01

Heatwaves are predicted to increase in frequency, duration, and severity in the future, including over Central Europe where populations are sensitive to extreme temperature. This paper studies six recent major heatwave events over Poland from 2006 through 2015 using regional-scale simulations (10-km grid spacing, hourly frequency) from the Weather Research and Forecast (WRF) model to define local-scale 2-m temperature patterns. For this purpose, a heatwave is defined as at least three consecutive days with maximum 2-m air temperature exceeding 30 °C. The WRF simulations were validated using maximum daily 2-m temperature observations from 12 meteorological stations in select Polish cities, which were selected to have even spatial coverage across the study area. Synoptic analysis of the six study events shows that the inflow of tropical air masses from the south is the primary driver of heatwave onset and maintenance, the highest temperatures (and most vulnerable areas) occur over arable land and artificial surfaces in central and western Poland, while coastal areas in the north, mountain areas in the south, and forested and mosaic areas of smaller fields and pastures of the northwest, northeast, and southeast are less affected by prolonged periods of elevated temperatures. In general, regional differences in 2-m temperature between the hottest and coolest areas is about 2-4 °C. Large urban areas like Warsaw, or the large complex of artificial areas in the conurbation of Silesian cities, are also generally warmer than surrounding areas by roughly 2-4 °C, and even up to 6 °C, especially during the night. Additionally, hot air from the south of Poland flows through a low-lying area between two mountain ranges (Sudetes and Carpathian Mountains)—the so-called Moravian Gate—hitting densely populated urban areas (Silesian cities) and Cracow. These patterns occur only during high-pressure synoptic conditions with low cloudiness and wind and without any active fronts

Seismic moment tensor resolution on a local scale: Simulated rockburst and mine-induced seismic events in the Kopanang gold mine, South Africa

CSIR Research Space (South Africa)

Sileny, J

2006-08-01

Full Text Available of regional events in the western Mediterranean are summarized by STICH et al. (2003). The moderate regional events around Japan are documented in the NIED catalogue by KUBO et al. (2002). Several case studies were performed to invert short- period records... and Metallurgy 101, 223? 234. Vol. 163, 2006 Seismic Moment Tensor Resolution on a Local Scale 1511 KRAVANJA, S., PANZA, G.F., and S? I? LENY? , J. (1999), Robust retrieval of a seismic point-source time function, Geophys. J. Int. 136, 385?394. KUBO, A., FUKUYAMA...

Structured Event-B Models and Proofs

DEFF Research Database (Denmark)

Hallerstede, Stefan

2010-01-01

Event-B does not provide specific support for the modelling of problems that require some structuring, such as, local variables or sequential ordering of events. All variables need to be declared globally and sequential ordering of events can only be achieved by abstract program counters. This ha...

Diagnosing causes of extreme aerosol optical depth events

Science.gov (United States)

Bernstein, D. N.; Sullivan, R.; Crippa, P.; Thota, A.; Pryor, S. C.

2017-12-01

Aerosol burdens and optical properties exhibit substantial spatiotemporal variability, and simulation of current and possible future aerosol burdens and characteristics exhibits relatively high uncertainty due to uncertainties in emission estimates and in chemical and physical processes associated with aerosol formation, dynamics and removal. We report research designed to improve understanding of the causes and characteristics of extreme aerosol optical depth (AOD) at the regional scale, and diagnose and attribute model skill in simulating these events. Extreme AOD events over the US Midwest are selected by identifying all dates on which AOD in a MERRA-2 reanalysis grid cell exceeds the local seasonally computed 90th percentile (p90) value during 2004-2016 and then finding the dates on which the highest number of grid cells exceed their local p90. MODIS AOD data are subsequently used to exclude events dominated by wildfires. MERRA-2 data are also analyzed within a synoptic classification to determine in what ways the extreme AOD events are atypical and to identify possible meteorological `finger-prints' that can be detected in regional climate model simulations of future climate states to project possible changes in the occurrence of extreme AOD. Then WRF-Chem v3.6 is applied at 12-km resolution and regridded to the MERRA-2 resolution over eastern North America to quantify model performance, and also evaluated using in situ measurements of columnar AOD (AERONET) and near-surface PM2.5 (US EPA). Finally the sensitivity to (i) spin-up time (including procedure used to spin-up the chemistry), (ii) modal versus sectional aerosol schemes, (iii) meteorological nudging, (iv) chemistry initial and boundary conditions, and (v) anthropogenic emissions is quantified. Despite recent declines in mean AOD, supraregional (> 1000 km) extreme AOD events continue to occur. During these events AOD exceeds 0.6 in many Midwestern grid cells for multiple consecutive days. In all

Hierarchical fault diagnosis for discrete-event systems under local consistency

NARCIS (Netherlands)

Su, Rong; Wonham, W.M.

2006-01-01

In previous work the authors proposed a distributed diagnosis approach consisting of two phases—preliminary diagnosis in each local diagnoser and inter-diagnoser communication. The objective of communication is to achieve either global or local consistency among local diagnoses, where global

Using ESSEA Modules, Local Event Studies and Personal Learning Experiences in an Earth Systems Science Course for Preservice Middle School Teachers

Science.gov (United States)

Slattery, W.; Brown, D.

2008-12-01

Most science courses, including courses that provide preparation for pre-service K-12 teachers are only taught from a deductive big picture perspective. This method is fine for most abstract learners, but pre- service classroom educators that are being prepared to teach in middle school classrooms will be faced with the challenge of building science content knowledge in students that are concrete learners. For these K-12 students a better pedagogical practice is to use local real-world familiar places, issues and personal experience to connect student learning with more abstract concepts. To make it more likely that teachers have the requisite skills and pedagogical content knowledge to build K- 12 student science concept knowledge and science process skills we have integrated ESSEA modules that connect worldwide issues such as global climate change with local event studies chosen by learners. Some recent examples include how such local events such as landfill fires and suburban sprawl impact the local area's air, land, water and life. Course participants are able to choose a more personal route to understanding how their habits impact the global environment by participating in a three week learning experience called the Lifestyle Project. This experience asks students to incrementally reduce their use of heating or air-conditioning, the amount of waste going to landfills, to conserve electricity, drive less and eat less energy intensively. Pre-post content assessments indicate that students in this course scored significantly higher on post course content assessments and reported that by engaging in personal experience to global scale learning experiences they have a new appreciation for how personal choices impact the global environment and how to use local artifacts and issues to enhance K-12 student learning.

Local therapy in localized Ewing tumors: results of 1058 patients treated in the CESS 81, CESS 86, and EICESS 92 trials

International Nuclear Information System (INIS)

Schuck, Andreas; Ahrens, Susanne; Paulussen, Michael; Kuhlen, Michaela; Koenemann, Stefan; Ruebe, Christian; Winkelmann, Winfried; Kotz, Rainer; Dunst, Juergen; Willich, Normann; Juergens, Heribert

2003-01-01

Purpose: The impact of different local therapy approaches on local control, event-free survival, and secondary malignancies in the CESS 81, CESS 86, and EICESS 92 trials was investigated. Methods and Materials: The data of 1058 patients with localized Ewing tumors were analyzed. Wherever feasible, a surgical local therapy approach was used. In patients with a poor histologic response or with intralesional and marginal resections, this was to be followed by radiotherapy (RT). In EICESS 92, preoperative RT was introduced for patients with expected close resection margins. Definitive RT was used in cases in which surgical resection seemed impossible. In CESS 81, vincristine, adriamycin, cyclophosphamide, and actinomycin D was used. In CESS 86, vincristine, adriamycin, ifosfamide, and actinomycin D was introduced for patients with central tumors or primaries >100 cm 3 . In CESS 92, etoposide, vincristine, adriamycin, ifosfamide, and actinomycin D was randomized against vincristine, adriamycin, ifosfamide, and actinomycin D in patients with primaries >100 cm 3 . Results: The rate of local failure was 7.5% after surgery with or without postoperative RT, and was 5.3% after preoperative and 26.3% after definitive RT (p=0.001). Event-free survival was reduced after definitive RT (p=0.0001). Irradiated patients represented a negatively selected population with unfavorable tumor sites. Definitive RT showed comparable local control to that of postoperative RT after intralesional resections. Patients with postoperative RT had improved local control after intralesional resections and in tumors with wide resection and poor histologic response compared with patients receiving surgery alone. Patients with marginal resections with or without postoperative radiotherapy showed comparable local control, yet the number of patients with good histologic response was higher in the latter treatment group (72.2% vs. 38.5%). Conclusion: Patients with resectable tumors after initial

Event-by-Event Elliptic Flow Fluctuations from PHOBOS

Science.gov (United States)

Wosiek, B.; Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Chetluru, V.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Harnarine, I.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Richardson, E.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Szostak, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Willhelm, D.; Wolfs, F. L. H.; Woźniak, K.; Wyngaardt, S.; Wysłouch, B.

2009-04-01

Recently PHOBOS has focused on the study of fluctuations and correlations in particle production in heavy-ion collisions at the highest energies delivered by the Relativistic Heavy Ion Collider (RHIC). In this report, we present results on event-by-event elliptic flow fluctuations in (Au+Au) collisions at sqrt {sNN}=200 GeV. A data-driven method was used to estimate the dominant contribution from non-flow correlations. Over the broad range of collision centralities, the observed large elliptic flow fluctuations are in agreement with the fluctuations in the initial source eccentricity.

75 FR 748 - Special Local Regulation for Marine Events; Recurring Marine Events in the Fifth Coast Guard...

Science.gov (United States)

2010-01-06

... recurring marine events within the Fifth Coast Guard District. These regulations make minor changes to the... includes but is not limited to sail boat regattas, boat parades, power boat racing, swimming events, crew racing, and sail board racing. Under figure 2-1, paragraph (34)(h), of the Instruction, an environmental...

Creating an Event: Case “Spring Festival” in Imatra

OpenAIRE

Serous, Alina

2014-01-01

The purpose of the project was to create a new event in Imatra, Finland, and to see how theoretical approach to event management is applied in practice. The event was designed to be public non-profit event for local families. The work was carried out in co-operation with Imitsi, the local association of town businesses, which aims at improving business environment and developing the town centre of Imatra to be a lively place. Theoretical background for the project was gathered using variou...

Initiative for local district heating. New chances for municipal utilities. Boundary conditions for the heat market; Initiative Nahwaerme. Neue Chancen fuer Stadtwerke. Rahmenbedingungen fuer den Waermemarkt

Energy Technology Data Exchange (ETDEWEB)

Koenig, Michael [K.Group GmbH, Muenchen (Germany). Bereich Nachhaltige Energieversorgung und Stadtentwicklung

2009-06-15

In the regulated market, municipal utilities are forced to find new fields of activity. The heat market offers good chances. For example, local district heating grids can be established, independent power generation can be encouraged, and new services can be offered which may increase customer loyalty. The district heating initiative of the Baden-Wuerttemberg Minister of the Environment was launched early in 2009 with the intention to offer valuable assistance to the municipal utilities. (orig.)

A Probabilistic Approach to Network Event Formation from Pre-Processed Waveform Data

Science.gov (United States)

Kohl, B. C.; Given, J.

2017-12-01

The current state of the art for seismic event detection still largely depends on signal detection at individual sensor stations, including picking accurate arrivals times and correctly identifying phases, and relying on fusion algorithms to associate individual signal detections to form event hypotheses. But increasing computational capability has enabled progress toward the objective of fully utilizing body-wave recordings in an integrated manner to detect events without the necessity of previously recorded ground truth events. In 2011-2012 Leidos (then SAIC) operated a seismic network to monitor activity associated with geothermal field operations in western Nevada. We developed a new association approach for detecting and quantifying events by probabilistically combining pre-processed waveform data to deal with noisy data and clutter at local distance ranges. The ProbDet algorithm maps continuous waveform data into continuous conditional probability traces using a source model (e.g. Brune earthquake or Mueller-Murphy explosion) to map frequency content and an attenuation model to map amplitudes. Event detection and classification is accomplished by combining the conditional probabilities from the entire network using a Bayesian formulation. This approach was successful in producing a high-Pd, low-Pfa automated bulletin for a local network and preliminary tests with regional and teleseismic data show that it has promise for global seismic and nuclear monitoring applications. The approach highlights several features that we believe are essential to achieving low-threshold automated event detection: Minimizes the utilization of individual seismic phase detections - in traditional techniques, errors in signal detection, timing, feature measurement and initial phase ID compound and propagate into errors in event formation, Has a formalized framework that utilizes information from non-detecting stations, Has a formalized framework that utilizes source information, in

De-Virtualizing Social Events: Understanding the Gap between Online and Offline Participation for Event Invitations

OpenAIRE

Huang, Ai-Ju; Wang, Hao-Chuan; Yuan, Chien Wen

2013-01-01

One growing use of computer-based communication media is for gathering people to initiate or sustain social events. Although the use of computer-mediated communication and social network sites such as Facebook for event promotion is becoming popular, online participation in an event does not always translate to offline attendance. In this paper, we report on an interview study of 31 participants that examines how people handle online event invitations and what influences their online and offl...

Event Investigation

International Nuclear Information System (INIS)

Korosec, D.

2000-01-01

The events in the nuclear industry are investigated from the license point of view and from the regulatory side too. It is well known the importance of the event investigation. One of the main goals of such investigation is to prevent the circumstances leading to the event and the consequences of the event. The protection of the nuclear workers against nuclear hazard, and the protection of general public against dangerous effects of an event could be achieved by systematic approach to the event investigation. Both, the nuclear safety regulatory body and the licensee shall ensure that operational significant events are investigated in a systematic and technically sound manner to gather information pertaining to the probable causes of the event. One of the results should be appropriate feedback regarding the lessons of the experience to the regulatory body, nuclear industry and general public. In the present paper a general description of systematic approach to the event investigation is presented. The systematic approach to the event investigation works best where cooperation is present among the different divisions of the nuclear facility or regulatory body. By involving management and supervisors the safety office can usually improve their efforts in the whole process. The end result shall be a program which serves to prevent events and reduce the time and efforts solving the root cause which initiated each event. Selection of the proper method for the investigation and an adequate review of the findings and conclusions lead to the higher level of the overall nuclear safety. (author)

On the Use of Hydrogen Recombination Energy during Common Envelope Events

Science.gov (United States)

Ivanova, Natalia

2018-05-01

In this Letter we discuss what happens to hydrogen recombination energy that is released during regular common envelope (CE) events as opposed to self-regulated CE events. We show that the amount of recombination energy that can be transferred away by either convection or radiation from the regions where recombination takes place is negligible. Instead, recombination energy is destined to be used either to help CE expansion, as a work term, or to accelerate local fluid elements. The exceptions are donors that initially have very high entropy material, S/(k B N A) > 37 mol g‑1. The analysis and conclusions are independent of specific stellar models or evolutionary codes, and rely on fundamental properties of stellar matter such as the equation of state, Saha equation, and opacities, as well as on stellar structure equations and the mixing length theory of convection.

Ownership dynamics in local multi-stakeholder initiatives

NARCIS (Netherlands)

K. Biekart (Kees); A.F. Fowler (Alan)

2018-01-01

textabstractThe nature and dynamics of ownership are often neglected features of multi-stakeholder initiatives (MSIs). Seventeen cases in four countries illustrate characteristics of narrow government or broad societal ownership and forces for change over time. Refinements to the application of

The initial impact of EU ETS verification events on stock prices

International Nuclear Information System (INIS)

Brouwers, Roel; Schoubben, Frederiek; Van Hulle, Cynthia; Van Uytbergen, Steve

2016-01-01

This paper studies the impact of verified emissions publications in the European Emissions Trading Scheme (EU ETS) on the market value of participating companies. Using event study methodology on a unique sample of 368 listed companies, we show that verified emissions only resulted in statistically significant market responses when the carbon price was high and allowance scarcity was anticipated. The cross-section analysis of abnormal returns surrounding the publication of verified emissions shows that share prices decrease when actual emissions relative to allocated emissions increase. This negative relationship between allocation shortfalls and firm value is only significant for firms that are either carbon-intensive, compared to sector peers, or are less likely to pass through carbon-related costs in their product prices. The results suggest that although the EU ETS has been deemed unsuccessful so far due to over-allocation and low carbon price, shareholders initially perceived allowance holdings as value relevant. Our results highlight that a significant carbon market price and addressing pass-through costing are essential for successful future reforms of the EU ETS and other analogous carbon cap-and-trade systems implemented or planned worldwide. - Highlights: •We study the impact of EU ETS verified emissions disclosure on firms' market value. •Disclosure is relevant if carbon price is high and permits scarcity is anticipated. •We find a negative relationship between allocation shortfalls and firm value. •Stronger relationship for carbon – intensive and no cost pass-through firms. •High carbon price and addressing cost pass-through are crucial for EU ETS reforms.

Event-by-Event Fluctuations of Azimuthal Particle Anisotropy in Au+Au Collisions at sNN=200GeV

Science.gov (United States)

Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wysłouch, B.

2010-04-01

This Letter presents the first measurement of event-by-event fluctuations of the elliptic flow parameter v2 in Au+Au collisions at sNN=200GeV as a function of collision centrality. The relative nonstatistical fluctuations of the v2 parameter are found to be approximately 40%. The results, including contributions from event-by-event elliptic flow fluctuations and from azimuthal correlations that are unrelated to the reaction plane (nonflow correlations), establish an upper limit on the magnitude of underlying elliptic flow fluctuations. This limit is consistent with predictions based on spatial fluctuations of the participating nucleons in the initial nuclear overlap region. These results provide important constraints on models of the initial state and hydrodynamic evolution of relativistic heavy ion collisions.

Seeding Event: Creating and Developing Spaces of Entrepreneurial Freedom

Directory of Open Access Journals (Sweden)

Gaëtan Mourmant

2012-12-01

Full Text Available This paper addresses the question of initiating, fostering and growing a vibrant economy by developing Spaces of Entrepreneurial Freedom (SoEF. Establishing and developing the SoEF is explained by a seeding event which is the core category of this grounded theory. In short, a seeding event leads to the patching of a potential, structural “hole”, which may prove valuable to an entrepreneurial network. Seeding events are started by an initiator who will recognize a network opportunity and exploit it. After event designing, the initiators implement the event through bold experimentation and using an adaptive structure. If the event is considered successful, the next stages are refining, growing, templating and finally replicating; these stages may occur one after the other or simultaneously. Through the development of SoEF, we suggest that entrepreneurs, governments, universities, large companies, and other players in the business world can improve the development of entrepreneurship at their respective levels.

Simulation of Flash-Flood-Producing Storm Events in Saudi Arabia Using the Weather Research and Forecasting Model

KAUST Repository

Deng, Liping

2015-05-01

The challenges of monitoring and forecasting flash-flood-producing storm events in data-sparse and arid regions are explored using the Weather Research and Forecasting (WRF) Model (version 3.5) in conjunction with a range of available satellite, in situ, and reanalysis data. Here, we focus on characterizing the initial synoptic features and examining the impact of model parameterization and resolution on the reproduction of a number of flood-producing rainfall events that occurred over the western Saudi Arabian city of Jeddah. Analysis from the European Centre for Medium-Range Weather Forecasts (ECMWF) interim reanalysis (ERA-Interim) data suggests that mesoscale convective systems associated with strong moisture convergence ahead of a trough were the major initial features for the occurrence of these intense rain events. The WRF Model was able to simulate the heavy rainfall, with driving convective processes well characterized by a high-resolution cloud-resolving model. The use of higher (1 km vs 5 km) resolution along the Jeddah coastline favors the simulation of local convective systems and adds value to the simulation of heavy rainfall, especially for deep-convection-related extreme values. At the 5-km resolution, corresponding to an intermediate study domain, simulation without a cumulus scheme led to the formation of deeper convective systems and enhanced rainfall around Jeddah, illustrating the need for careful model scheme selection in this transition resolution. In analysis of multiple nested WRF simulations (25, 5, and 1 km), localized volume and intensity of heavy rainfall together with the duration of rainstorms within the Jeddah catchment area were captured reasonably well, although there was evidence of some displacements of rainstorm events.

Residents’ Support in Major Local Events: Leeds Pride.

OpenAIRE

Pappas, Nikolaos

2016-01-01

This article examines the extent to which community participation and perceived impacts have an influence on residents' support of major events, more specifically, the Leeds Pride celebration. The research examines the perspectives of 400 Leeds permanent residents. The study tests a structural equation model, which has its theoretical basis in social exchange theory. It examines the constructs of community participation, perceived positive and negative impacts, and community support, includin...

Localized palmar-plantar epidermal hyperplasia: a previously undefined dermatologic toxicity to sorafenib.

Science.gov (United States)

Beldner, Matthew; Jacobson, Michael; Burges, Gene E; Dewaay, Deborah; Maize, John C; Chaudhary, Uzair B

2007-10-01

The development of multitargeted tyrosine kinase inhibitors has provided significant advances in the treatment of renal cell carcinoma. This case describes initial therapy for managing renal cell cancer with the administration of sorafenib, a multitargeted tyrosine kinase inhibitor. We report the development of localized palmar-plantar epidermal hyperplasia, a rare but significant cutaneous adverse event from sorafenib therapy. Mild-to-moderate dermatologic toxicity from sorafenib has been well described in the literature. We also review the current knowledge and the proposed hypothesis for the development of cutaneous events related to tyrosine kinase inhibitors. This particular case represents a unique form of dermatologic toxicity to sorafenib that has not previously been described in the literature.

Multi-channel control circuit for real-time control of events in Aditya tokamak

Energy Technology Data Exchange (ETDEWEB)

Edappala, Praveenlal, E-mail: praveen@ipr.res.in; Shah, Minsha; Rajpal, Rachana; Tanna, R.L.; Ghosh, Joydeep; Chattopadhyay, P.K.; Jha, R.

2016-11-15

Highlights: • Low cost microcontroller based control circuit. • The control hardware can be programmed/configured very easily for different applications. • Microcontroller programming is done in assembly language so that precise timing can be achieved with micro seconds resolution. • Successful implementation of this circuit in noisy tokamak environment. • Efficient noise and burst elimination. • Can be integrated in to the other subsystems. • Low cost solution for implementing feedback control in small and medium size tokamaks and other experiments requiring feedback control. - Abstract: Tokamak plasma is prone to many random events having potential for causing severe damages to the machine, such as disruptions, production and elimination of high-energy runaway electrons etc. These events can be mitigated by obtaining pre-cursor signal leading to these events and then taking proper measures just before their onset to avoid their happenings, like disruptions can be mitigated by massive gas injection or putting a bias voltage on an electrode placed inside the plasma, the runaways can be mitigated by gas injection and by applying specific magnetic fields. Hence for real time control of these events, the pre-cursors should be electronically recorded and the mitigation techniques should be initiated by sending triggers to their individual operational systems. To implement these methodologies of real-time controlling of events in Aditya Tokamak, a low cost multi-channel Micro-Controller based timing circuit is designed and developed in-house. This circuit first compares the precursor signals fed into it with the pre-set values and gives a trigger output whenever the signals overshoot the pre-set values. The circuit readies itself for operation along with start of the tokamak discharge and waits up to an initial pre-determined delay and then initiates a trigger at the time of overshooting of precursor signal. The circuit is fully integrated and assembled in

Trends and characteristics observed in nuclear events based on international nuclear event scale reports

International Nuclear Information System (INIS)

Watanabe, Norio

2001-01-01

The International Nuclear Event Scale (INES) is jointly operated by the IAEA and the OECD-NEA as a means designed for providing prompt, clear and consistent information related to nuclear events, that occurred at nuclear facilities, and facilitating communication between the nuclear community, the media and the public. Nuclear events are reported to the INES with the Scale', a consistent safety significance indicator, which runs from level 0, for events with no safety significance, to level 7 for a major accident with widespread health and environmental effects. Since the operation of INES was initiated in 1990, approximately 500 events have been reported and disseminated. The present paper discusses the trends observed in nuclear events, such as overall trends of the reported events and characteristics of safety significant events with level 2 or higher, based on the INES reports. (author)

RECONSTRUCTING THE INITIAL DENSITY FIELD OF THE LOCAL UNIVERSE: METHODS AND TESTS WITH MOCK CATALOGS

International Nuclear Information System (INIS)

Wang Huiyuan; Mo, H. J.; Yang Xiaohu; Van den Bosch, Frank C.

2013-01-01

Our research objective in this paper is to reconstruct an initial linear density field, which follows the multivariate Gaussian distribution with variances given by the linear power spectrum of the current cold dark matter model and evolves through gravitational instabilities to the present-day density field in the local universe. For this purpose, we develop a Hamiltonian Markov Chain Monte Carlo method to obtain the linear density field from a posterior probability function that consists of two components: a prior of a Gaussian density field with a given linear spectrum and a likelihood term that is given by the current density field. The present-day density field can be reconstructed from galaxy groups using the method developed in Wang et al. Using a realistic mock Sloan Digital Sky Survey DR7, obtained by populating dark matter halos in the Millennium simulation (MS) with galaxies, we show that our method can effectively and accurately recover both the amplitudes and phases of the initial, linear density field. To examine the accuracy of our method, we use N-body simulations to evolve these reconstructed initial conditions to the present day. The resimulated density field thus obtained accurately matches the original density field of the MS in the density range 0.3∼ –1 , much smaller than the translinear scale, which corresponds to a wavenumber of ∼0.15 h Mpc –1

Localization and Broadband Follow-up of the Gravitational-wave Transient GW150914

Science.gov (United States)

Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Barthelmy, S.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Bustillo, J. C.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Diaz, J. C.; Casentini, C.; Caudill, S.; Cavagliá, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Baiardi, L. C.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M., Jr.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. 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D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Haris, K.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Hollitt, S. E.; Holt, K.; Holz, D. E.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huang, S.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J.-M.; Isi, M.; Islas, G.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jang, H.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. 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V.; Negro, M.; Nuss, E.; Ohsugi, T.; Omodei, N.; Orienti, M.; Orlando, E.; Ormes, J. F.; Paneque, D.; Perkins, J. S.; Pesce-Rollins, M.; Piron, F.; Pivato, G.; Porter, T. A.; Racusin, J. L.; Rainò, S.; Rando, R.; Razzaque, S.; Reimer, A.; Reimer, O.; Salvetti, D.; Saz Parkinson, P. M.; Sgrò, C.; Simone, D.; Siskind, E. J.; Spada, F.; Spandre, G.; Spinelli, P.; Suson, D. J.; Tajima, H.; Thayer, J. B.; Thompson, D. J.; Tibaldo, L.; Torres, D. F.; Troja, E.; Uchiyama, Y.; Venters, T. M.; Vianello, G.; Wood, K. S.; Wood, M.; Zhu, S.; Zimmer, S.; Fermi LAT Collaboration; Brocato, E.; Cappellaro, E.; Covino, S.; Grado, A.; Nicastro, L.; Palazzi, E.; Pian, E.; Amati, L.; Antonelli, L. A.; Capaccioli, M.; D'Avanzo, P.; D'Elia, V.; Getman, F.; Giuffrida, G.; Iannicola, G.; Limatola, L.; Lisi, M.; Marinoni, S.; Marrese, P.; Melandri, A.; Piranomonte, S.; Possenti, A.; Pulone, L.; Rossi, A.; Stamerra, A.; Stella, L.; Testa, V.; Tomasella, L.; Yang, S.; GRAvitational Wave Inaf TeAm (GRAWITA); Bazzano, A.; Bozzo, E.; Brandt, S.; Courvoisier, T. J.-L.; Ferrigno, C.; Hanlon, L.; Kuulkers, E.; Laurent, P.; Mereghetti, S.; Roques, J. P.; Savchenko, V.; Ubertini, P.; INTEGRAL Collaboration; Kasliwal, M. M.; Singer, L. P.; Cao, Y.; Duggan, G.; Kulkarni, S. R.; Bhalerao, V.; Miller, A. A.; Barlow, T.; Bellm, E.; Manulis, I.; Rana, J.; Laher, R.; Masci, F.; Surace, J.; Rebbapragada, U.; Cook, D.; Van Sistine, A.; Sesar, B.; Perley, D.; Ferreti, R.; Prince, T.; Kendrick, R.; Horesh, A.; Intermediate Palomar Transient Factory (iPTF Collaboration); Hurley, K.; Golenetskii, S. V.; Aptekar, R. L.; Frederiks, D. D.; Svinkin, D. S.; Rau, A.; von Kienlin, A.; Zhang, X.; Smith, D. M.; Cline, T.; Krimm, H.; InterPlanetary Network; Abe, F.; Doi, M.; Fujisawa, K.; Kawabata, K. S.; Morokuma, T.; Motohara, K.; Tanaka, M.; Ohta, K.; Yanagisawa, K.; Yoshida, M.; J-GEM Collaboration; Baltay, C.; Rabinowitz, D.; Ellman, N.; Rostami, S.; La Silla-QUEST Survey; Bersier, D. F.; Bode, M. F.; Collins, C. A.; Copperwheat, C. M.; Darnley, M. J.; Galloway, D. K.; Gomboc, A.; Kobayashi, S.; Mazzali, P.; Mundell, C. G.; Piascik, A. S.; Pollacco, Don; Steele, I. A.; Ulaczyk, K.; Liverpool Telescope Collaboration; Broderick, J. W.; Fender, R. P.; Jonker, P. G.; Rowlinson, A.; Stappers, B. W.; Wijers, R. A. M. J.; Low Frequency Array (LOFAR Collaboration); Lipunov, V.; Gorbovskoy, E.; Tyurina, N.; Kornilov, V.; Balanutsa, P.; Kuznetsov, A.; Buckley, D.; Rebolo, R.; Serra-Ricart, M.; Israelian, G.; Budnev, N. M.; Gress, O.; Ivanov, K.; Poleshuk, V.; Tlatov, A.; Yurkov, V.; MASTER Collaboration; Kawai, N.; Serino, M.; Negoro, H.; Nakahira, S.; Mihara, T.; Tomida, H.; Ueno, S.; Tsunemi, H.; Matsuoka, M.; MAXI Collaboration; Croft, S.; Feng, L.; Franzen, T. M. O.; Gaensler, B. M.; Johnston-Hollitt, M.; Kaplan, D. L.; Morales, M. F.; Tingay, S. J.; Wayth, R. B.; Williams, A.; Murchison Wide-field Array (MWA Collaboration); Smartt, S. J.; Chambers, K. C.; Smith, K. W.; Huber, M. E.; Young, D. R.; Wright, D. E.; Schultz, A.; Denneau, L.; Flewelling, H.; Magnier, E. A.; Primak, N.; Rest, A.; Sherstyuk, A.; Stalder, B.; Stubbs, C. W.; Tonry, J.; Waters, C.; Willman, M.; Pan-STARRS Collaboration; Olivares E., F.; Campbell, H.; Kotak, R.; Sollerman, J.; Smith, M.; Dennefeld, M.; Anderson, J. P.; Botticella, M. T.; Chen, T.-W.; Della Valle, M.; Elias-Rosa, N.; Fraser, M.; Inserra, C.; Kankare, E.; Kupfer, T.; Harmanen, J.; Galbany, L.; Le Guillou, L.; Lyman, J. D.; Maguire, K.; Mitra, A.; Nicholl, M.; Razza, A.; Terreran, G.; Valenti, S.; Gal-Yam, A.; PESSTO Collaboration; Ćwiek, A.; Ćwiok, M.; Mankiewicz, L.; Opiela, R.; Zaremba, M.; Żarnecki, A. F.; Pi of Sky Collaboration; Onken, C. A.; Scalzo, R. A.; Schmidt, B. P.; Wolf, C.; Yuan, F.; SkyMapper Collaboration; Evans, P. A.; Kennea, J. A.; Burrows, D. N.; Campana, S.; Cenko, S. B.; Giommi, P.; Marshall, F. E.; Nousek, J.; O'Brien, P.; Osborne, J. P.; Palmer, D.; Perri, M.; Siegel, M.; Tagliaferri, G.; Swift Collaboration; Klotz, A.; Turpin, D.; Laugier, R.; TAROT Collaboration; Zadko Collaboration; Algerian National Observatory Collaboration; C2PU Collaboration; Beroiz, M.; Peñuela, T.; Macri, L. M.; Oelkers, R. J.; Lambas, D. G.; Vrech, R.; Cabral, J.; Colazo, C.; Dominguez, M.; Sanchez, B.; Gurovich, S.; Lares, M.; Marshall, J. L.; DePoy, D. L.; Padilla, N.; Pereyra, N. A.; Benacquista, M.; TOROS Collaboration; Tanvir, N. R.; Wiersema, K.; Levan, A. J.; Steeghs, D.; Hjorth, J.; Fynbo, J. P. U.; Malesani, D.; Milvang-Jensen, B.; Watson, D.; Irwin, M.; Fernandez, C. G.; McMahon, R. G.; Banerji, M.; Gonzalez-Solares, E.; Schulze, S.; de Ugarte Postigo, A.; Thoene, C. C.; Cano, Z.; Rosswog, S.; VISTA Collaboration

2016-07-01

A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams.

LOCALIZATION AND BROADBAND FOLLOW-UP OF THE GRAVITATIONAL-WAVE TRANSIENT GW150914

Energy Technology Data Exchange (ETDEWEB)

Abbott, B. P.; Abbott, R.; Abernathy, M. R.; Adhikari, R. X. [LIGO, California Institute of Technology, Pasadena, CA 91125 (United States); Abbott, T. D. [Louisiana State University, Baton Rouge, LA 70803 (United States); Acernese, F.; Addesso, P. [Università di Salerno, Fisciano, I-84084 Salerno (Italy); Ackley, K. [University of Florida, Gainesville, FL 32611 (United States); Adams, C. [LIGO Livingston Observatory, Livingston, LA 70754 (United States); Adams, T. [Laboratoire d’Annecy-le-Vieux de Physique des Particules (LAPP), Université Savoie Mont Blanc, CNRS/IN2P3, F-74941 Annecy-le-Vieux (France); Adya, V. B.; Affeldt, C.; Allen, B. [Albert-Einstein-Institut, Max-Planck-Institut für Gravitationsphysik, D-30167 Hannover (Germany); Agathos, M.; Agatsuma, K. [Nikhef, Science Park, 1098 XG Amsterdam (Netherlands); Aggarwal, N. [LIGO, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Aguiar, O. D. [Instituto Nacional de Pesquisas Espaciais, 12227-010 São José dos Campos, SP (Brazil); Aiello, L. [INFN, Gran Sasso Science Institute, I-67100 L’Aquila (Italy); Ain, A. [Inter-University Centre for Astronomy and Astrophysics, Pune 411007 (India); Ajith, P., E-mail: lsc-spokesperson@ligo.org, E-mail: virgo-spokesperson@ego-gw.eu, E-mail: Julie.E.McEnery@nasa.gov [International Centre for Theoretical Sciences, Tata Institute of Fundamental Research, Bangalore 560012 (India); Collaboration: LIGO Scientific Collaboration and the Virgo Collaboration; Australian Square Kilometer Array Pathfinder (ASKAP) Collaboration; BOOTES Collaboration; Dark Energy Survey and the Dark Energy Camera GW-EM Collaborations; Fermi GBM Collaboration; Fermi LAT Collaboration; GRAvitational Wave Inaf TeAm (GRAWITA); INTEGRAL Collaboration; Intermediate Palomar Transient Factory (iPTF) Collaboration; InterPlanetary Network; J-GEM Collaboration; La Silla–QUEST Survey; Liverpool Telescope Collaboration; Low Frequency Array (LOFAR) Collaboration; MASTER Collaboration; MAXI Collaboration; Murchison Wide-field Array (MWA) Collaboration; Pan-STARRS Collaboration; PESSTO Collaboration; Pi of the Sky Collaboration; SkyMapper Collaboration; Swift Collaboration; TAROT, Zadko, Algerian National Observatory, and C2PU Collaboration; TOROS Collaboration; VISTA Collaboration; and others

2016-07-20

A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams.

LOCALIZATION AND BROADBAND FOLLOW-UP OF THE GRAVITATIONAL-WAVE TRANSIENT GW150914

International Nuclear Information System (INIS)

Abbott, B. P.; Abbott, R.; Abernathy, M. R.; Adhikari, R. X.; Abbott, T. D.; Acernese, F.; Addesso, P.; Ackley, K.; Adams, C.; Adams, T.; Adya, V. B.; Affeldt, C.; Allen, B.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.

2016-01-01

A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams.

Managing the Urban Image. Cities as Scenery for Events: A White Night Event as a Case Study

Directory of Open Access Journals (Sweden)

ELENI ATHANASOPOULOU

2015-12-01

Full Text Available Organizing street events in the cities is not something new. Many cultural, social or religious events take place on the streets, whereas many of them have become international events and attract pan-european attention and coverage. Mega cities are organizing festivals and cultural events in order to attract tourists and contribute to local and regional development. This trend has started growing and spreading around Europe. Medium-sized cities are also organising such multi-dimensional public space events. As a case study it is interesting to present a white night event that took place in Kalamata (a medium-sized city in southern Greece, in August 2013. The shops stayed open until 3 in the morning, offering their products at reduced prices and encouraging people to consume. The city center provided the scenery for an alternative massive celebration. Parties were thrown and concerts took place, around the city. Many people from the Kalamata Region visited Kalamata City. The success was unexpected. This article describes what good can come out of the adoption of a successful north-European cultural white night event (in St. Petersburg and elsewhere. The implementation of an interesting idea, adjusted to the local circumstances, is worth to be looked into. The article concludes that urban scenery can play an important role to the organisation and success of such multicultural events.

Contributions to dataflow sub-system of the ATLAS data acquisition and event filter prototype-1 project

International Nuclear Information System (INIS)

Badescu, E.; Caprini, M.; Niculescu, M.; Radu, A.

1998-01-01

A project has been approved by the ATLAS Collaboration for the design and implementation of a Data Acquisition (DAQ) and Event Filter (EF) prototype. The prototype consists of a full 'vertical' slice of the ATLAS Data Acquisition and Event Filter architecture and can be seen as made of 4 sub-systems: the Detector Interface, the Dataflow, the Back-end DAQ and the Event Filter. The Bucharest group is member of DAQ/EF collaboration and during 1997 it was involved in the Dataflow activities. The Dataflow component of the ATLAS DAQ/EF prototype is responsible for moving the event data from the detector read-out links to the final mass storage. It also provides event data for monitoring purposes and implements local control for the various elements. The Dataflow system is designed to cover three main functions, namely: the collection and buffering of the data from the detector, the merging of fragments into full events and the interaction with event filter sub-farm. The event building function is covered by a Dataflow building block named Event Builder. All the other functions of the Dataflow system are covered by the two modular building blocks, the read-out crate (ROC) and the sub-farm DAQ (SFC). The Bucharest group was mainly involved in the activities related to the high level design, initial implementation and tests of the ROC supporting the read-out from one or more read-out drivers and having one or more connections to the event builder. The main data flow within the ROC is handled by three input/output modules named IOMs: the trigger module (TRG), the event builder interface module (EBIF) and the read-out buffer module (ROB). The TRG receives and buffers data control messages from level 1 and from level 2 trigger system, the EBIF builds fragments and makes them available to the event building sub-system and the ROB receives and buffers ROB fragments from the read-out link, S-LINK. In order to estimate the performance which could be achieved with the actual

Initiating events study of the first extraction cycle process in a model reprocessing plant

Energy Technology Data Exchange (ETDEWEB)

Wang, Renze; Zhang, Jian Gang; Zhuang, Dajie; Feng, Zong Yang [China Institute for Radiation Protection, Taiyuan (China)

2016-06-15

Definition and grouping of initiating events (IEs) are important basics for probabilistic safety assessment (PSA). An IE in a spent fuel reprocessing plant (SFRP) is an event that probably leads to the release of dangerous material to jeopardize workers, public and environment. The main difference between SFRPs and nuclear power plants (NPPs) is that hazard materials spread diffusely in a SFRP and radioactive material is just one kind of hazard material. Since the research on IEs for NPPs is in-depth around the world, there are several general methods to identify IEs: reference of lists in existence, review of experience feedback, qualitative analysis method, and deductive analysis method. While failure mode and effect analysis (FMEA) is an important qualitative analysis method, master logic diagram (MLD) method is the deductive analysis method. IE identification in SFRPs should be consulted with the experience of NPPs, however the differences between SFRPs and NPPs should be considered seriously. The plutonium uranium reduction extraction (Purex) process is adopted by the technics in a model reprocessing plant. The first extraction cycle (FEC) is the pivotal process in the Purex process. Whether the FEC can function safely and steadily would directly influence the production process of the whole plant-production quality. Important facilities of the FEC are installed in the equipment cells (ECs). In this work, IEs in the FEC process were identified and categorized by FMEA and MLD two methods, based on the fact that ECs are containments in the plant. The results show that only two ECs in the FEC do not need to be concerned particularly with safety problems, and criticality, fire and red oil explosion are IEs which should be emphatically analyzed. The results are accordant with the references.

A Network of AOPs for reduced thyroid hormone synthesis derived from inhibition of Thyroperoxidase - A common Molecular Initiating Event Leading to Species-Specific Indices of Adversity.

Science.gov (United States)

This collection of 3 AOPs describe varying outcomes of adversity dependent upon species in response to inhibition of thyroperoxidase (TPO) during development. Chemical inhibition of TPO, the molecular-initiating event (MIE), results in decreased thyroid hormone (TH) synthesis, a...

[Initial subretinal localization of acute myeloblastic leukemia (AML5) recurrence].

Science.gov (United States)

Le Gall, S; François, S; Urier, N; Genevieve, F; d'Hermies, F; Rachieru, P; Ifrah, N

2001-10-13

Reduced visual acuity in patients with acute leucemia can result from many causes including an ocular localization. A patient previously treated for acute myeloblastic leucemia-5 (AML5) developed bilateral vision impairment related to a subretinal localization of the leucemia. Meningeal and bone marrow relapse followed. The subretinal localization responded only to massive systemic steroid treatment. Although asymptomatic, ocular localizations are frequent in leucemia. Their prognostic impact depends on the ocular structure involved and on the chronology of onset--early or late in the leucemia course. The underlying pathophysiological mechanism of ocular involvement remains unexplained but hyperleucocytosis at presentation may be a risk factor and would justify at least systematic specialized examinations and discussion of prophylactic treatment.

Energy network dispatch optimization under emergency of local energy shortage

International Nuclear Information System (INIS)

Cai, Tianxing; Zhao, Chuanyu; Xu, Qiang

2012-01-01

The consequence of short-time energy shortage under extreme conditions, such as earthquake, tsunami, and hurricane, may cause local areas to suffer from delayed rescues, widespread power outages, tremendous economic losses, and even public safety threats. In such urgent events of local energy shortage, agile energy dispatching through an effective energy transportation network, targeting the minimum energy recovery time, should be a top priority. In this paper, a novel methodology is developed for energy network dispatch optimization under emergency of local energy shortage, which includes four stages of work. First, emergency-area-centered energy network needs to be characterized, where the capacity, quantity, and availability of various energy sources are determined. Second, the energy initial situation under emergency conditions needs to be identified. Then, the energy dispatch optimization is conducted based on a developed MILP (mixed-integer linear programming) model in the third stage. Finally, the sensitivity of the minimum dispatch time with respect to uncertainty parameters is characterized by partitioning the entire space of uncertainty parameters into multiple subspaces. The efficacy of the developed methodology is demonstrated via a case study with in-depth discussions. -- Highlights: ► Address the energy network dispatch problem under emergency of local energy shortage. ► Minimize the energy restoration time for the entire energy network under emergency events. ► Develop a new MILP model and a sensitivity analysis method with respect to uncertainties.

Synchronous Parallel System for Emulation and Discrete Event Simulation

Science.gov (United States)

Steinman, Jeffrey S. (Inventor)

2001-01-01

A synchronous parallel system for emulation and discrete event simulation having parallel nodes responds to received messages at each node by generating event objects having individual time stamps, stores only the changes to the state variables of the simulation object attributable to the event object and produces corresponding messages. The system refrains from transmitting the messages and changing the state variables while it determines whether the changes are superseded, and then stores the unchanged state variables in the event object for later restoral to the simulation object if called for. This determination preferably includes sensing the time stamp of each new event object and determining which new event object has the earliest time stamp as the local event horizon, determining the earliest local event horizon of the nodes as the global event horizon, and ignoring events whose time stamps are less than the global event horizon. Host processing between the system and external terminals enables such a terminal to query, monitor, command or participate with a simulation object during the simulation process.

The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein

International Nuclear Information System (INIS)

Parreiras-e-Silva, Lucas T.; Gomes, Marcelo D.; Oliveira, Eduardo B.; Costa-Neto, Claudio M.

2007-01-01

The eukaryotic translation initiation factor 5A (eIF5A) is a ubiquitous protein of eukaryotic and archaeal organisms which undergoes hypusination, a unique post-translational modification. We have generated a polyclonal antibody against murine eIF5A, which in immunocytochemical assays in B16-F10 cells revealed that the endogenous protein is preferentially localized to the nuclear region. We therefore analyzed possible structural features present in eIF5A proteins that could be responsible for that characteristic. Multiple sequence alignment analysis of eIF5A proteins from different eukaryotic and archaeal organisms showed that the former sequences have an extended N-terminal segment. We have then performed in silico prediction analyses and constructed different truncated forms of murine eIF5A to verify any possible role that the N-terminal extension might have in determining the subcellular localization of the eIF5A in eukaryotic organisms. Our results indicate that the N-terminal extension of the eukaryotic eIF5A contributes in signaling this protein to nuclear localization, despite of bearing no structural similarity with classical nuclear localization signals

Statistical Analysis of Interchange Injection Events from Over a Decade of Cassini Data

Science.gov (United States)

Azari, A.; Jia, X.; Liemohn, M. W.; Sergis, N.; Thomsen, M. F.; Mitchell, D. G.; Rymer, A. M.; Paranicas, C.; Provan, G.; Ye, S.; Cowley, S. W. H.; Hospodarsky, G. B.; Vandegriff, J. D.; Kurth, W. S.

2017-12-01

The Cassini spacecraft has routinely observed interchange injection events with multiple instruments since arriving at Saturn in 2004. Interchange injection events are thought to initiate from a Rayleigh-Taylor like plasma instability sourced from Saturn's rapid rotation (period 10.8 hours) and dense plasma population outgassing primarily from Enceladus, and are the primary source of mass transport in the inner/middle magnetosphere. This dense plasma must be transported outward, and to conserve magnetic flux, inward moving flux tubes of low density, energetic (> keV) plasma from the outer reaches of the Saturnian system also occur. These inward-bound flux tubes are referred to as interchange injections. We will present a statistical evaluation of the occurrence rates of interchange injections at Saturn demonstrating seasonal dependence of interchange over the entirety of the Cassini mission's equatorial orbits between 2005 and 2016. We identify interchange events from CHarge Energy Mass Spectrometer (CHEMS) H+ data using a trained and tested automated algorithm. Our event identification compares well with manual identification and previous surveys of injections by L-shell and local time (Chen and Hill, 2008, Lai et al., 2016, Kennelly et al., 2013). We find that peak rates of interchange events occur between 7 - 9 Saturn radii, in agreement with previous surveys. We also evaluate interchange by preferred local time sector and season, splitting our events into pre-equinox, equinox, and post - equinox time periods. We determine that over all seasons, nightside occurrence dominated as compared to dayside, but the preferred dayside sector shifts from pre-noon during equinox, to post-noon during post-equinox. We will further investigate seasonal dependence by presenting occurrence organized by the phase systems derived based on Saturn kilometric radiation (SKR) and magnetic field perturbations (PPO).

Time-dependent importance sampling in semiclassical initial value representation calculations for time correlation functions.

Science.gov (United States)

Tao, Guohua; Miller, William H

2011-07-14

An efficient time-dependent importance sampling method is developed for the Monte Carlo calculation of time correlation functions via the initial value representation (IVR) of semiclassical (SC) theory. A prefactor-free time-dependent sampling function weights the importance of a trajectory based on the magnitude of its contribution to the time correlation function, and global trial moves are used to facilitate the efficient sampling the phase space of initial conditions. The method can be generally applied to sampling rare events efficiently while avoiding being trapped in a local region of the phase space. Results presented in the paper for two system-bath models demonstrate the efficiency of this new importance sampling method for full SC-IVR calculations.

Brain ischemia as initial sign of a left atrial myxoma Report of one case

International Nuclear Information System (INIS)

Osio, Luis F; Velasquez, Jorge E; Tobon, Gabriel J; Posada, Gloria; Contreras, Eduardo; Sanchez, Jairo; Gutierrez, Javier

2008-01-01

Primary heart tumors are rare; 75% of them are benign and almost half of the benign ones are myxomas that in most cases are located in the left cavities. Clinical manifestations of myxomas depend on its localization site. Nevertheless, it is accepted that brain ischemia is the initial clinical manifestation in a third of atrial myxomas. The case of a 65 years ald male patient in whom the first clinical manifestation of an atrial myxoma was an ischemic cerebrovascular event, is presented

Long-Term Outcome and Toxicity of Salvage Brachytherapy for Local Failure After Initial Radiotherapy for Prostate Cancer

International Nuclear Information System (INIS)

Burri, Ryan J.; Stone, Nelson N.; Unger, Pam; Stock, Richard G.

2010-01-01

Purpose: To describe long-term outcomes and toxicity after salvage brachytherapy (BT) for local failure after initial radiotherapy for prostate cancer. Methods and Materials: Between 1994 and 2008, 37 men with local failure after initial prostate radiotherapy (32 external-beam radiation therapy [EBRT] and 5 BT) underwent salvage BT with 103 Pd or 125 I. Estimates of freedom from biochemical failure (FFbF, Phoenix definition) and cause-specific survival (CSS) were calculated using the Kaplan-Meier method. Toxicities were graded using CTCv3.0. Results: Median follow-up was 86 months (range, 2-156). The median dose to 90% of the prostate volume was 122 Gy (range, 67-166). The 10-year FFbF and CSS were 54% and 96%, respectively. On univariate analysis, prostate-specific antigen (PSA) >10 ng/mL at initial diagnosis was significantly associated with FFbF (p = 0.01), and there were trends for both age <70 years (p = 0.08) and PSA <6 ng/mL (p = 0.08) at the time of salvage BT. On multivariate analysis, only presalvage PSA <6 ng/mL (p = 0.046) was significantly associated with improved FFbF. There were three Grade 3 toxicities and one Grade 4 toxicity. Pelvic lymph node dissection before salvage BT was the only variable significantly associated with Grade ≥2 toxicity (p = 0.03). Conclusion: With a median follow-up of 86 months, salvage prostate BT was associated with a 10-year FFbF of 54% and CSS of 96%. Improved FFbF was associated with a presalvage PSA <6 ng/mL. Toxicity was worse in patients who had undergone pelvic lymph node dissection before salvage BT. Careful patient selection for salvage BT may result in improved outcomes and reduced toxicity.

Factors affecting initial disability allowance rates for the Disability Insurance and Supplemental Security Income programs: the role of the demographic and diagnostic composition of applicants and local labor market conditions.

Science.gov (United States)

Rupp, Kalman

2012-01-01

Various factors outside the control of decision makers may affect the rate at which disability applications are allowed or denied during the initial step of eligibility determination in the Social Security Disability Insurance (DI) and Supplemental Security Income (SSI) programs. In this article, using individual-level data on applications, I estimate the role of three important factors--the demographic characteristics of applicants, the diagnostic mix of applicants, and the local unemployment rate--in affecting the probability of an initial allowance and state allowance rates. I use a random sample of initial determinations from 1993 through 2008 and a fixed-effects multiple regression framework. The empirical results show that the demographic and diagnostic characteristics of applicants and the local unemployment rate substantially affect the initial allowance rate. An increase in the local unemployment rate tends to be associated with a decrease in the initial allowance rate. This negative relationship holds for adult DI and SSI applicants and for SSI childhood applicants.

The underlying event in hard scattering processes

International Nuclear Information System (INIS)

Field, R.

2002-01-01

The authors study the behavior of the underlying event in hard scattering proton-antiproton collisions at 1.8 TeV and compare with the QCD Monte-Carlo models. The underlying event is everything except the two outgoing hard scattered jets and receives contributions from the beam-beam remnants plus initial and final-state radiation. The data indicate that neither ISAJET or HERWIG produce enough charged particles (with p T > 0.5 GeV/c) from the beam-beam remnant component and that ISAJET produces too many charged particles from initial-state radiation. PYTHIA which uses multiple parton scattering to enhance the underlying event does the best job describing the data

Traditional folk event with national importance: The impact of visitors’ age

Directory of Open Access Journals (Sweden)

Petra Solarová

2016-04-01

Full Text Available In the context of the cultural tourism, this paper focuses on the traditional folk event with national importance that is held in the Czech Republic and its name is Porta. The aim is to assess characteristic traits and satisfaction of two age categories of Porta´s visitors. Through the realised research among visitors, the importance of segmentation was proved. Hence, it is crucial to focus on getting to know the visitors and their motivation. In addition to that, cultural events are also important for local government. According to the officials of local government, where this event is held, such events are able to attract visitors to the particular locality. However, they have only limited opportunities how to support these events (especially from the financial viewpoint.

Extreme events in total ozone: Spatio-temporal analysis from local to global scale

Science.gov (United States)

Rieder, Harald E.; Staehelin, Johannes; Maeder, Jörg A.; Ribatet, Mathieu; di Rocco, Stefania; Jancso, Leonhardt M.; Peter, Thomas; Davison, Anthony C.

2010-05-01

dynamics (NAO, ENSO) on total ozone is a global feature in the northern mid-latitudes (Rieder et al., 2010c). In a next step frequency distributions of extreme events are analyzed on global scale (northern and southern mid-latitudes). A specific focus here is whether findings gained through analysis of long-term European ground based stations can be clearly identified as a global phenomenon. By showing results from these three types of studies an overview of extreme events in total ozone (and the dynamical and chemical features leading to those) will be presented from local to global scales. References: Coles, S.: An Introduction to Statistical Modeling of Extreme Values, Springer Series in Statistics, ISBN:1852334592, Springer, Berlin, 2001. Ribatet, M.: POT: Modelling peaks over a threshold, R News, 7, 34-36, 2007. Rieder, H.E., Staehelin, J., Maeder, J.A., Ribatet, M., Stübi, R., Weihs, P., Holawe, F., Peter, T., and A.D., Davison (2010): Extreme events in total ozone over Arosa - Part I: Application of extreme value theory, to be submitted to ACPD. Rieder, H.E., Staehelin, J., Maeder, J.A., Ribatet, M., Stübi, R., Weihs, P., Holawe, F., Peter, T., and A.D., Davison (2010): Extreme events in total ozone over Arosa - Part II: Fingerprints of atmospheric dynamics and chemistry and effects on mean values and long-term changes, to be submitted to ACPD. Rieder, H.E., Jancso, L., Staehelin, J., Maeder, J.A., Ribatet, Peter, T., and A.D., Davison (2010): Extreme events in total ozone over the northern mid-latitudes: A case study based on long-term data sets from 5 ground-based stations, in preparation. Staehelin, J., Renaud, A., Bader, J., McPeters, R., Viatte, P., Hoegger, B., Bugnion, V., Giroud, M., and Schill, H.: Total ozone series at Arosa (Switzerland): Homogenization and data comparison, J. Geophys. Res., 103(D5), 5827-5842, doi:10.1029/97JD02402, 1998a. Staehelin, J., Kegel, R., and Harris, N. R.: Trend analysis of the homogenized total ozone series of Arosa

Radiologically isolated syndrome: 5-year risk for an initial clinical event.

Directory of Open Access Journals (Sweden)

Darin T Okuda

Full Text Available OBJECTIVE: To report the 5-year risk and to identify risk factors for the development of a seminal acute or progressive clinical event in a multi-national cohort of asymptomatic subjects meeting 2009 RIS Criteria. METHODS: Retrospectively identified RIS subjects from 22 databases within 5 countries were evaluated. Time to the first clinical event related to demyelination (acute or 12-month progression of neurological deficits was compared across different groups by univariate and multivariate analyses utilizing a Cox regression model. RESULTS: Data were available in 451 RIS subjects (F: 354 (78.5%. The mean age at from the time of the first brain MRI revealing anomalies suggestive of MS was 37.2 years (y (median: 37.1 y, range: 11-74 y with mean clinical follow-up time of 4.4 y (median: 2.8 y, range: 0.01-21.1 y. Clinical events were identified in 34% (standard error=3% of individuals within a 5-year period from the first brain MRI study. Of those who developed symptoms, 9.6% fulfilled criteria for primary progressive MS. In the multivariate model, age [hazard ratio (HR: 0.98 (95% CI: 0.96-0.99; p=0.03], sex (male [HR: 1.93 (1.24-2.99; p=0.004], and lesions within the cervical or thoracic spinal cord [HR: 3.08 (2.06-4.62; p=<0.001] were identified as significant predictors for the development of a first clinical event. INTERPRETATION: These data provide supportive evidence that a meaningful number of RIS subjects evolve to a first clinical symptom. An age <37 y, male sex, and spinal cord involvement appear to be the most important independent predictors of symptom onset.

77 FR 34215 - Special Local Regulations for Marine Events, Swim Event; Lake Gaston, Littleton, NC

Science.gov (United States)

2012-06-11

... material to the docket, call Renee V. Wright, Program Manager, Docket Operations, telephone (202) 366-9826... along the western side of Eaton Ferry Bridge to the Waterview Restaurant. A fleet of spectator vessels... operation of any support vessel participating in the event, at any time it is deemed necessary for the...

Local learning-networks on energy efficiency in industry - Successful initiative in Germany

International Nuclear Information System (INIS)

Jochem, Eberhard; Gruber, Edelgard

2007-01-01

Profitable energy-efficiency potentials are often not exploited in industry since management tends not to focus on energy issues. Sharing experiences between companies reveals possibilities for reducing the transaction costs involved. For this purpose, regionally or locally-organised learning networks of companies have been established. Social mechanisms are used to motivate management to pay more attention to energy efficiency in Switzerland and Germany. The main elements of the activities include initial consultation for each company with an experienced engineer, agreement on a common target for energy-efficiency improvement, regular meetings with technical presentations and an exchange of experiences, yearly control of energy consumption and CO 2 emissions as well as scientific monitoring and evaluation of the process. The results of some evaluations show that substantial progress has been made in implementing organisational measures and investments in energy efficiency in the participating companies. The reasons for these achievements are discussed and conclusions drawn about the opportunities and limits of this instrument. Finally, a recommendation is made to implement this instrument on a broader level

Fluctuating exciton localization in giant π-conjugated spoked-wheel macrocycles

Science.gov (United States)

Aggarwal, A. Vikas; Thiessen, Alexander; Idelson, Alissa; Kalle, Daniel; Würsch, Dominik; Stangl, Thomas; Steiner, Florian; Jester, Stefan-S.; Vogelsang, Jan; Höger, Sigurd; Lupton, John M.

2013-11-01

Conjugated polymers offer potential for many diverse applications, but we still lack a fundamental microscopic understanding of their electronic structure. Elementary photoexcitations (excitons) span only a few nanometres of a molecule, which itself can extend over microns, and how their behaviour is affected by molecular dimensions is not immediately obvious. For example, where is the exciton formed within a conjugated segment and is it always situated on the same repeat units? Here, we introduce structurally rigid molecular spoked wheels, 6 nm in diameter, as a model of extended π conjugation. Single-molecule fluorescence reveals random exciton localization, which leads to temporally varying emission polarization. Initially, this random localization arises after every photon absorption event because of temperature-independent spontaneous symmetry breaking. These fast fluctuations are slowed to millisecond timescales after prolonged illumination. Intramolecular heterogeneity is revealed in cryogenic spectroscopy by jumps in transition energy, but emission polarization can also switch without a spectral jump occurring, which implies long-range homogeneity in the local dielectric environment.

Events and Effects

DEFF Research Database (Denmark)

Rytter, Mikkel

2010-01-01

Analyzing the period of ‘intensive transnationalism’ among Pakistani migrants in Denmark precipitated by the 2005 earthquake in Kashmir, this article explores the relationship between events and effects on a global scale. One significant initiative after the disaster was the founding of an ad hoc......, and national identity politics in Denmark. Despite the medical doctors’ efforts and intentions, the out- come was framed by 9/11, which has become the major critical event of the decade—one that has supported a developing cleavage between the Danish majority and Denmark’s Muslim immigrant minority....

Impact of Pre-Initiators on PSA in Research Reactor

Energy Technology Data Exchange (ETDEWEB)

Ochirbat, Chimedtseren [KAIST, Daejeon (Korea, Republic of); Kim, Sok Chul [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

2014-10-15

Most of nuclear power plants had already conducted PSA work to examine their plant safety for identifying vulnerability and preparing the mitigating strategies for severe accident. However, the PSA for research reactor has been conducted limitedly comparing with nuclear power plants due to lack of awareness and resources. Most of PSA results demonstrated that human failure events (HFEs) take a major role of risk contributor in terms of core damage frequency. HFEs are categorized as the following three types: pre-initiating event interaction (e.g., maintenance of errors, testing errors, calibration errors), initiating event related interactions (e.g., human error causing loss of power, human error causing system trip), and post-initiating event (e.g., all action actuating manual safety system backup of an automatic system). Lack of resources and utilization of research reactor calls a vicious circle in terms of safety degradation. The safety degradation poses the vulnerability of human failure during research reactor utilization process. Typically, evaluation of pre-initiators related to test and maintenance are not taking into account in PSA for research reactors. This paper aims to investigate the impact of pre-initiating events related to test and maintenance activities on PSA results in terms of core damage frequency for a research reactor.

Impact of Pre-Initiators on PSA in Research Reactor

International Nuclear Information System (INIS)

Ochirbat, Chimedtseren; Kim, Sok Chul

2014-01-01

Most of nuclear power plants had already conducted PSA work to examine their plant safety for identifying vulnerability and preparing the mitigating strategies for severe accident. However, the PSA for research reactor has been conducted limitedly comparing with nuclear power plants due to lack of awareness and resources. Most of PSA results demonstrated that human failure events (HFEs) take a major role of risk contributor in terms of core damage frequency. HFEs are categorized as the following three types: pre-initiating event interaction (e.g., maintenance of errors, testing errors, calibration errors), initiating event related interactions (e.g., human error causing loss of power, human error causing system trip), and post-initiating event (e.g., all action actuating manual safety system backup of an automatic system). Lack of resources and utilization of research reactor calls a vicious circle in terms of safety degradation. The safety degradation poses the vulnerability of human failure during research reactor utilization process. Typically, evaluation of pre-initiators related to test and maintenance are not taking into account in PSA for research reactors. This paper aims to investigate the impact of pre-initiating events related to test and maintenance activities on PSA results in terms of core damage frequency for a research reactor

THE 2012 JULY 23 BACKSIDE ERUPTION: AN EXTREME ENERGETIC PARTICLE EVENT?

Energy Technology Data Exchange (ETDEWEB)

Gopalswamy, N. [Code 671, Solar Physics Laboratory, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Yashiro, S.; Thakur, N.; Mäkelä, P.; Xie, H.; Akiyama, S., E-mail: nat.gopalswamy@nasa.gov [Department of Physics, The Catholic University of America, Washington, DC 20064 (United States)

2016-12-20

The backside coronal mass ejection (CME) of 2012 July 23 had a short Sun-to-Earth shock transit time (18.5 hr). The associated solar energetic particle (SEP) event had a >10 MeV proton flux peaking at ∼5000 pfu, and the energetic storm particle event was an order of magnitude larger, making it the most intense event in the space era at these energies. By a detailed analysis of the CME, shock, and SEP characteristics, we find that the July 23 event is consistent with a high-energy SEP event (accelerating particles to gigaelectronvolt energies). The times of maximum and fluence spectra in the range 10–100 MeV were very hard, similar to those of ground-level enhancement (GLE) events. We found a hierarchical relationship between the CME initial speeds and the fluence spectral indices: CMEs with low initial speeds had SEP events with the softest spectra, while those with the highest initial speeds had SEP events with the hardest spectra. CMEs attaining intermediate speeds result in moderately hard spectra. The July 23 event was in the group of hard-spectrum events. During the July 23 event, the shock speed (>2000 km s{sup −1}), the initial acceleration (∼1.70 km s{sup −2}), and the shock-formation height (∼1.5 solar radii) were all typical of GLE events. The associated type II burst had emission components from meter to kilometer wavelengths, suggesting a strong shock. These observations confirm that the 2012 July 23 event is likely to be an extreme event in terms of the energetic particles it accelerated.

Modeling time to recovery and initiating event frequency for loss of off-site power incidents at nuclear power plants

International Nuclear Information System (INIS)

Iman, R.L.; Hora, S.C.

1988-01-01

Industry data representing the time to recovery of loss of off-site power at nuclear power plants for 63 incidents caused by plant-centered losses, grid losses, or severe weather losses are fit with exponential, lognormal, gamma and Weibull probability models. A Bayesian analysis is used to compare the adequacy of each of these models and to provide uncertainty bounds on each of the fitted models. A composite model that combines the probability models fitted to each of the three sources of data is presented as a method for predicting the time to recovery of loss of off-site power. The composite model is very general and can be made site specific by making adjustments on the models used, such as might occur due to the type of switchyard configuration or type of grid, and by adjusting the weights on the individual models, such as might occur with weather conditions existing at a particular plant. Adjustments in the composite model are shown for different models used for switchyard configuration and for different weights due to weather. Bayesian approaches are also presented for modeling the frequency of initiating events leading to loss of off-site power. One Bayesian model assumes that all plants share a common incidence rate for loss of off-site power, while the other Bayesian approach models the incidence rate for each plant relative to the incidence rates of all other plants. Combining the Bayesian models for the frequency of the initiating events with the composite Bayesian model for recovery provides the necessary vehicle for a complete model that incorporates uncertainty into a probabilistic risk assessment

Retrospective Evaluation of the Short-Term Sustainability of the Locally Grown Produce Initiative of the Hunger Prevention and Nutrition Assistance Program in New York State.

Science.gov (United States)

Allsopp, Marie A K; Hosler, Akiko S

2018-03-27

The Hunger Prevention and Nutrition Assistance Program (HPNAP) is a New York State Department of Health program. The HPNAP improves nutritional quality of food available at food banks, food pantries, soup kitchens, and emergency shelters through contractual relationships to fund the purchase, delivery, storage, and service of nutritious food. To determine whether a one-time fiscal stimulus of the Locally Grown Produce Initiative to HPNAP contractors in 2012-2013 would result in a short-term sustainable increase in the proportion of dollars spent on New York State Grown (NYSG) produce. Quasi-experimental, nonequivalent control group design. We analyzed New York State Department of Health administrative data regarding expenditures on all produce and NYSG produce by HPNAP contractors. New York State. The proportion of dollars spent on NYSG produce during 2011-2012 (preintervention) and 2013-2014 (postintervention) was compared between HPNAP food bank contractors (recipients of stimulus money, n = 8) and non-food bank contractors (nonrecipients, n = 34) using nonparametric methods. The HPNAP Locally Grown Produce Initiative was associated with an increased proportion of NYSG produce spending by food bank contractors that received a fiscal stimulus 1 year later. Upstate food banks had the largest increase (median 31.6%) among all HPNAP contractors. The results of this study revealed that the Locally Grown Produce Initiative fiscal stimulus had a positive, year-long and statewide effect on the proportion of expenditure on NYSG produce by food banks. We hope that the initial success seen in New York State may encourage other states to adopt similar initiatives in future.

Mining-induced seismicity at the Lucky Friday Mine: Seismic events of magnitude >2.5, 1989--1994

Energy Technology Data Exchange (ETDEWEB)

Whyatt, J.K.; Williams, T.J. [USDOE, Spokane, WA (United States). Spokane Research Center; Blake, W. [Blake (W.), Hayden Lake, ID (United States); Sprenke, K. [Idaho Univ., Moscow, ID (United States); Wideman, C. [Montana Tech, Butte, MT (United States)

1996-09-01

An understanding of the types of seismic events that occur in a deep mine provides a foundation for assessing the seismic characteristics of these events and the degree to which initiation of these events can be anticipated or controlled. This study is a first step toward developing such an understanding of seismic events generated by mining in the Coeur d`Alene Mining District of northern Idaho. It is based on information developed in the course of a long-standing rock burst research effort undertaken by the U. S. Bureau of Mines in cooperation with Coeur d`Alene Mining District mines and regional universities. This information was collected for 39 seismic events with local magnitudes greater than 2.5 that occurred between 1989 and 1994. One of these events occurred, on average, every 8 weeks during the study period. Five major types of characteristic events were developed from the data; these five types describe all but two of the 39 events that were studied. The most common types of events occurred, on average, once every 30 weeks. The characteristic mechanisms, first-motion patterns, damage patterns, and relationships to mining and major geologic structures were defined for each type of event. These five types of events need to be studied further to assess their ability to camouflage clandestine nuclear tests as well as the degree to which they can be anticipated and controlled.

Satellite-Enhanced Dynamical Downscaling of Extreme Events

Science.gov (United States)

Nunes, A.

2015-12-01

Severe weather events can be the triggers of environmental disasters in regions particularly susceptible to changes in hydrometeorological conditions. In that regard, the reconstruction of past extreme weather events can help in the assessment of vulnerability and risk mitigation actions. Using novel modeling approaches, dynamical downscaling of long-term integrations from global circulation models can be useful for risk analysis, providing more accurate climate information at regional scales. Originally developed at the National Centers for Environmental Prediction (NCEP), the Regional Spectral Model (RSM) is being used in the dynamical downscaling of global reanalysis, within the South American Hydroclimate Reconstruction Project. Here, RSM combines scale-selective bias correction with assimilation of satellite-based precipitation estimates to downscale extreme weather occurrences. Scale-selective bias correction is a method employed in the downscaling, similar to the spectral nudging technique, in which the downscaled solution develops in agreement with its coarse boundaries. Precipitation assimilation acts on modeled deep-convection, drives the land-surface variables, and therefore the hydrological cycle. During the downscaling of extreme events that took place in Brazil in recent years, RSM continuously assimilated NCEP Climate Prediction Center morphing technique precipitation rates. As a result, RSM performed better than its global (reanalysis) forcing, showing more consistent hydrometeorological fields compared with more sophisticated global reanalyses. Ultimately, RSM analyses might provide better-quality initial conditions for high-resolution numerical predictions in metropolitan areas, leading to more reliable short-term forecasting of severe local storms.

A test for Improvement of high resolution Quantitative Precipitation Estimation for localized heavy precipitation events

Science.gov (United States)

Lee, Jung-Hoon; Roh, Joon-Woo; Park, Jeong-Gyun

2017-04-01

Accurate estimation of precipitation is one of the most difficult and significant tasks in the area of weather diagnostic and forecasting. In the Korean Peninsula, heavy precipitations are caused by various physical mechanisms, which are affected by shortwave trough, quasi-stationary moisture convergence zone among varying air masses, and a direct/indirect effect of tropical cyclone. In addition to, various geographical and topographical elements make production of temporal and spatial distribution of precipitation is very complicated. Especially, localized heavy rainfall events in South Korea generally arise from mesoscale convective systems embedded in these synoptic scale disturbances. In weather radar data with high temporal and spatial resolution, accurate estimation of rain rate from radar reflectivity data is too difficult. Z-R relationship (Marshal and Palmer 1948) have adapted representatively. In addition to, several methods such as support vector machine (SVM), neural network, Fuzzy logic, Kriging were utilized in order to improve the accuracy of rain rate. These methods show the different quantitative precipitation estimation (QPE) and the performances of accuracy are different for heavy precipitation cases. In this study, in order to improve the accuracy of QPE for localized heavy precipitation, ensemble method for Z-R relationship and various techniques was tested. This QPE ensemble method was developed by a concept based on utilizing each advantage of precipitation calibration methods. The ensemble members were produced for a combination of different Z-R coefficient and calibration method.

Local government units initiatives on coastal resource management in adjacent municipalities in Camarines Sur, Philippines

Science.gov (United States)

Faustino, A. Z.; Madela, H. L.

2018-03-01

This research was conducted to determine the local government units (LGUs) initiatives on coastal resource management (CRM) in adjacent municipalities in Camarines Sur, Philippines. The respondents of this study are 100 fisherfolk leaders in the municipalities of Calabanga, Tinambac and Siruma. Descriptive, comparative and evaluative methods of research were employed and a survey questionnaire was used as the primary tool in data gathering. On the test of difference, the computed F-value of 12.038 and p-value of .001 revealed a very high difference in the implementation of CRM initiatives in the adjacent municipalities. The respondents in this study live below the poverty threshold. The intrusion of commercial fishers and the use of active fishing gears inside the 15-km municipal waters significantly affect the marine habitat while fishpond conversion kills the natural cycle in the mangrove forests. However, the FOs membership in the Municipal Fisheries and Aquatic Resources Management Council empower them to engage in governance which can be a venue for them to recommend policies related to CRM. As a result of this study, a CRM monitoring and evaluation model was crafted to guide the LGUs in the review, revision and crafting of CRM programs.

New PHOBOS results on event-by-event fluctuations

Science.gov (United States)

Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Chai, Z.; Chetluru, V.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Heintzelman, G. A.; Henderson, C.; Harnarine, I.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Reed, C.; Remsberg, L. P.; Reuter, M.; Richardson, E.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Sedykh, I.; Skulski, W.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Szostak, A.; Tang, J.-L.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Willhelm, D.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wyngaardt, S.; Wysłouch, B.

2006-04-01

We present new results from the PHOBOS experiment at RHIC on event-by-event fluctuations of particle multiplicities and angular distributions in nucleus-nucleus collisions at RHIC. Our data for Au+Au collisions at √sNN = 200 GeV show that at a level of 10-4 or less, no rare, large-amplitude fluctuations in the total multiplicity distributions or the shape of the pseudorapidity distributions are observed. We however find significant short-range multiplicity correlations in these data, that can be described as particle production in clusters. In Cu+Cu collisions, we observe large final-state azimuthal anisotropies ν2. A common scaling behavior for Cu+Cu and Au+Au for these anisotropies emerges when fluctuations in the initial state geometry are taken into account.

Local Side Effects of Sublingual and Oral Immunotherapy.

Science.gov (United States)

Passalacqua, Giovanni; Nowak-Węgrzyn, Anna; Canonica, Giorgio Walter

Sublingual immunotherapy (SLIT) is increasingly used worldwide, and several products have been recently registered as drugs for respiratory allergy by the European Medicine Agency and the Food and Drug Administration. Concerning inhalant allergens, the safety of SLIT is overall superior to that of subcutaneous immunotherapy in terms of systemic adverse events. No fatality has been ever reported, and episodes of anaphylaxis were described only exceptionally. Looking at the historical and recent trials, most (>90%) adverse events are "local" and confined to the site of administration. For this reason, a specific grading system has been developed by the World Allergy Organization to classify and describe local adverse events. There is an increasing amount of literature concerning oral desensitization for food allergens, referred to as oral immunotherapy. Also, in this case, local side effects are predominant, although systemic adverse events are more frequent than with inhalant allergens. We review herein the description of local side effects due to SLIT, with a special focus on large trials having a declared sample size calculation. The use of the Medical Dictionary for Regulatory Activities nomenclature for adverse events is mentioned in this context, as recommended by regulatory agencies. It is expected that a uniform classification/grading of local adverse events will improve and harmonize the surveillance and reporting on the safety of SLIT. Copyright © 2016 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Nightside High Latitude Magnetic Impulse Events

Science.gov (United States)

Engebretson, M. J.; Connors, M. G.; Braun, D.; Posch, J. L.; Kaur, M.; Guillon, S.; Hartinger, M.; Kim, H.; Behlke, R.; Reiter, K.; Jackel, B. J.; Russell, C. T.

2017-12-01

High latitude Magnetic Impulse Events (MIEs), isolated pulses with periods 5-10 min, were first noted in ground-based magnetometer data near local noon, and are now understood to be signatures of transient pressure increases in the solar wind (sudden impulses - SIs) and/or in the ion foreshock (traveling convection vortex events - TCVs). However, solitary pulses with considerably larger amplitude (ΔB up to 1500 nT) have often been observed in the night sector at these same latitudes. These events are not directly associated with transient external pressure increases, and are often large enough to produce significant ground induced currents. Although many night sector MIEs occur in association with substorm signatures, others appear to be very isolated. We present here a survey of intense MIE events identified in magnetometer data from the AUTUMNX and MACCS arrays in eastern Arctic Canada at all local times between July 1, 2014 and June 30, 2017. We also show maps of horizontal and vertical perturbations and maximum dB/dt values, as well as sample magnetograms, for several example events using data from these and other arrays in Arctic Canada, as well as in West Greenland and Antarctica, the latter to show the conjugate nature of these events. A basic relation to GIC data in the Hydro-Québec electrical transmission network in eastern Canada has been determined and will be discussed.

Mechanisms of sharp wave initiation and ripple generation.

Science.gov (United States)

Schlingloff, Dániel; Káli, Szabolcs; Freund, Tamás F; Hájos, Norbert; Gulyás, Attila I

2014-08-20

Replay of neuronal activity during hippocampal sharp wave-ripples (SWRs) is essential in memory formation. To understand the mechanisms underlying the initiation of irregularly occurring SWRs and the generation of periodic ripples, we selectively manipulated different components of the CA3 network in mouse hippocampal slices. We recorded EPSCs and IPSCs to examine the buildup of neuronal activity preceding SWRs and analyzed the distribution of time intervals between subsequent SWR events. Our results suggest that SWRs are initiated through a combined refractory and stochastic mechanism. SWRs initiate when firing in a set of spontaneously active pyramidal cells triggers a gradual, exponential buildup of activity in the recurrent CA3 network. We showed that this tonic excitatory envelope drives reciprocally connected parvalbumin-positive basket cells, which start ripple-frequency spiking that is phase-locked through reciprocal inhibition. The synchronized GABA(A) receptor-mediated currents give rise to a major component of the ripple-frequency oscillation in the local field potential and organize the phase-locked spiking of pyramidal cells. Optogenetic stimulation of parvalbumin-positive cells evoked full SWRs and EPSC sequences in pyramidal cells. Even with excitation blocked, tonic driving of parvalbumin-positive cells evoked ripple oscillations. Conversely, optogenetic silencing of parvalbumin-positive cells interrupted the SWRs or inhibited their occurrence. Local drug applications and modeling experiments confirmed that the activity of parvalbumin-positive perisomatic inhibitory neurons is both necessary and sufficient for ripple-frequency current and rhythm generation. These interneurons are thus essential in organizing pyramidal cell activity not only during gamma oscillation, but, in a different configuration, during SWRs. Copyright © 2014 the authors 0270-6474/14/3411385-14$15.00/0.

Ownership dynamics in local multi-stakeholder initiatives

OpenAIRE

Biekart, Kees; Fowler, Alan

2018-01-01

textabstractThe nature and dynamics of ownership are often neglected features of multi-stakeholder initiatives (MSIs). Seventeen cases in four countries illustrate characteristics of narrow government or broad societal ownership and forces for change over time. Refinements to the application of Gaventa’s Power Cube are used to analyse such shifts from the perspective of invited and closed spaces for participation. Observations about ways in which stakeholder groups can create a more enabling ...

Ultrafast hydrogen exchange reveals specific structural events during the initial stages of folding of cytochrome c.

Science.gov (United States)

Fazelinia, Hossein; Xu, Ming; Cheng, Hong; Roder, Heinrich

2014-01-15

Many proteins undergo a sharp decrease in chain dimensions during early stages of folding, prior to the rate-limiting step in folding. However, it remains unclear whether compact states are the result of specific folding events or a general hydrophobic collapse of the poly peptide chain driven by the change in solvent conditions. To address this fundamental question, we extended the temporal resolution of NMR-detected H/D exchange labeling experiments into the microsecond regime by adopting a microfluidics approach. By observing the competition between H/D exchange and folding as a function of labeling pH, coupled with direct measurement of exchange rates in the unfolded state, we were able to monitor hydrogen-bond formation for over 50 individual backbone NH groups within the initial 140 microseconds of folding of horse cytochrome c. Clusters of solvent-shielded amide protons were observed in two α-helical segments in the C-terminal half of the protein, while the N-terminal helix remained largely unstructured, suggesting that proximity in the primary structure is a major factor in promoting helix formation and association at early stages of folding, while the entropically more costly long-range contacts between the N- and C-terminal helices are established only during later stages. Our findings clearly indicate that the initial chain condensation in cytochrome c is driven by specific interactions among a subset of α-helical segments rather than a general hydrophobic collapse.

Investigation on relationship between epicentral distance and growth curve of initial P-wave propagating in local heterogeneous media for earthquake early warning system

Science.gov (United States)

Okamoto, Kyosuke; Tsuno, Seiji

2015-10-01

In the earthquake early warning (EEW) system, the epicenter location and magnitude of earthquakes are estimated using the amplitude growth rate of initial P-waves. It has been empirically pointed out that the growth rate becomes smaller as epicentral distance becomes far regardless of the magnitude of earthquakes. So, the epicentral distance can be estimated from the growth rate using this empirical relationship. However, the growth rates calculated from different earthquakes at the same epicentral distance mark considerably different values from each other. Sometimes the growth rates of earthquakes having the same epicentral distance vary by 104 times. Qualitatively, it has been considered that the gap in the growth rates is due to differences in the local heterogeneities that the P-waves propagate through. In this study, we demonstrate theoretically how local heterogeneities in the subsurface disturb the relationship between the growth rate and the epicentral distance. Firstly, we calculate seismic scattered waves in a heterogeneous medium. First-ordered PP, PS, SP, and SS scatterings are considered. The correlation distance of the heterogeneities and fractional fluctuation of elastic parameters control the heterogeneous conditions for the calculation. From the synthesized waves, the growth rate of the initial P-wave is obtained. As a result, we find that a parameter (in this study, correlation distance) controlling heterogeneities plays a key role in the magnitude of the fluctuation of the growth rate. Then, we calculate the regional correlation distances in Japan that can account for the fluctuation of the growth rate of real earthquakes from 1997 to 2011 observed by K-NET and KiK-net. As a result, the spatial distribution of the correlation distance shows locality. So, it is revealed that the growth rates fluctuate according to the locality. When this local fluctuation is taken into account, the accuracy of the estimation of epicentral distances from initial P

Trending analysis of precursor events

International Nuclear Information System (INIS)

Watanabe, Norio

1998-01-01

The Accident Sequence Precursor (ASP) Program of United States Nuclear Regulatory Commission (U.S.NRC) identifies and categorizes operational events at nuclear power plants in terms of the potential for core damage. The ASP analysis has been performed on yearly basis and the results have been published in the annual reports. This paper describes the trends in initiating events and dominant sequences for 459 precursors identified in the ASP Program during the 1969-94 period and also discusses a comparison with dominant sequences predicted in the past Probabilistic Risk Assessment (PRA) studies. These trends were examined for three time periods, 1969-81, 1984-87 and 1988-94. Although the different models had been used in the ASP analyses for these three periods, the distribution of precursors by dominant sequences show similar trends to each other. For example, the sequences involving loss of both main and auxiliary feedwater were identified in many PWR events and those involving loss of both high and low coolant injection were found in many BWR events. Also, it was found that these dominant sequences were comparable to those determined to be dominant in the predictions by the past PRAs. As well, a list of the 459 precursors identified are provided in Appendix, indicating initiating event types, unavailable systems, dominant sequences, conditional core damage probabilities, and so on. (author)

How to Fund Homeland Security without Federal Dollars: State and Local Funding of Homeland Security Initiatives in Light of Decreased Support by the Federal Government

National Research Council Canada - National Science Library

Emler, Jay S

2008-01-01

.... This thesis, therefore, examined alternatives states and local units of government might use to fund homeland security initiatives, ranging from conventional alternatives such as, asset forfeiture...

32 CFR 705.34 - Other special events.

Science.gov (United States)

2010-07-01

...-cause fund-raising event may be authorized if the event is: (i) In support of Navy recruiting objectives...) Official functions. (1) Navy units may be authorized by local commanding officers to participate in official government military and civic functions, except in the Washington DC area where OASD(PA) retains...

Risk assessment of K Basin twelve-inch and four-inch drain valve failure from a postulated seismic initiating event

Energy Technology Data Exchange (ETDEWEB)

MORGAN, R.G.

1999-06-23

The Spent Nuclear Fuel (SNF) Project will transfer metallic SNF from the Hanford 105 K-East and 105 K-West Basins to safe interim storage in the Canister Storage Building in the 200 Area. The initial basis for design, fabrication, installation, and operation of the fuel removal systems was that the basin leak rate which could result from a postulated accident condition would not be excessive relative to reasonable recovery operations. However, an additional potential K Basin water leak path is through the K Basin drain valves. Three twelve-inch drain valves are located in the main basin bays along the north wall. Five four-inch drain valves are located in the north and south loadout pits (NLOP and SLOP), the weasel pit, the technical viewing pit, and the discharge chute pit. The sumps containing the valves are filled with concrete which covers the drain valve body. Visual observations indicate that only the valve's bonnet and stem are exposed above the basin concrete floor for the twelve-inch drain valve and that much less of the valve's bonnet and stem are exposed above the basin concrete floor for the five four-inch drain valves. It was recognized, however, that damage of the drain valve bonnet or stem during a seismic initiating event could provide a potential K Basin water leak path. The objectives of this analysis are to: (1) evaluate the likelihood of damaging the three twelve-inch drain valves located along the north wall of the main basin and the five four-inch drain valves located in the pits from a seismic initiating event, and (2) determine the likelihood of exceeding a specific consequence (initial leak rate) from a damaged valve. The analysis process is a risk-based uncertainty analysis where each variable is modeled using available information and engineering judgement. The uncertainty associated with each variable is represented by a probability distribution (probability density function). Uncertainty exists because of the inherent

Quantifying the effect of Tmax extreme events on local adaptation to climate change of maize crop in Andalusia for the 21st century

Science.gov (United States)

Gabaldon, Clara; Lorite, Ignacio J.; Ines Minguez, M.; Lizaso, Jon; Dosio, Alessandro; Sanchez, Enrique; Ruiz-Ramos, Margarita

2015-04-01

Extreme events of Tmax can threaten maize production on Andalusia (Ruiz-Ramos et al., 2011). The objective of this work is to attempt a quantification of the effects of Tmax extreme events on the previously identified (Gabaldón et al., 2013) local adaptation strategies to climate change of irrigated maize crop in Andalusia for the first half of the 21st century. This study is focused on five Andalusia locations. Local adaptation strategies identified consisted on combinations of changes on sowing dates and choice of cultivar (Gabaldón et al., 2013). Modified cultivar features were the duration of phenological phases and the grain filling rate. The phenological and yield simulations with the adaptative changes were obtained from a modelling chain: current simulated climate and future climate scenarios (2013-2050) were taken from a group of regional climate models at high resolution (25 km) from the European Project ENSEMBLES (http://www.ensembles-eu.org/). After bias correcting these data for temperature and precipitation (Dosio and Paruolo, 2011; Dosio et al., 2012) crop simulations were generated by the CERES-maize model (Jones and Kiniry, 1986) under DSSAT platform, previously calibrated and validated. Quantification of the effects of extreme Tmax on maize yield was computed for different phenological stages following Teixeira et al. (2013). A heat stress index was computed; this index assumes that yield-damage intensity due to heat stress increases linearly from 0.0 at a critical temperature to a maximum of 1.0 at a limit temperature. The decrease of crop yield is then computed by a normalized production damage index which combines attainable yield and heat stress index for each location. Selection of the most suitable adaptation strategy will be reviewed and discussed in light of the quantified effect on crop yield of the projected change of Tmax extreme events. This study will contribute to MACSUR knowledge Hub within the Joint Programming Initiative on

Towards Optimal Event Detection and Localization in Acyclic Flow Networks

KAUST Repository

Agumbe Suresh, Mahima; Stoleru, Radu; Denton, Ron; Zechman, Emily; Shihada, Basem

2012-01-01

infrastructure (i.e., minimizing the number of sensor and beacon nodes deployed), while ensuring a degree of sensing coverage in a zone of interest and a required accuracy in locating events. We propose algorithms for solving these problems and demonstrate

Radiation induced apoptosis and initial DNA damage are inversely related in locally advanced breast cancer patients

International Nuclear Information System (INIS)

Pinar, Beatriz; Henríquez-Hernández, Luis Alberto; Lara, Pedro C; Bordon, Elisa; Rodriguez-Gallego, Carlos; Lloret, Marta; Nuñez, Maria Isabel; De Almodovar, Mariano Ruiz

2010-01-01

DNA-damage assays, quantifying the initial number of DNA double-strand breaks induced by radiation, have been proposed as a predictive test for radiation-induced toxicity. Determination of radiation-induced apoptosis in peripheral blood lymphocytes by flow cytometry analysis has also been proposed as an approach for predicting normal tissue responses following radiotherapy. The aim of the present study was to explore the association between initial DNA damage, estimated by the number of double-strand breaks induced by a given radiation dose, and the radio-induced apoptosis rates observed. Peripheral blood lymphocytes were taken from 26 consecutive patients with locally advanced breast carcinoma. Radiosensitivity of lymphocytes was quantified as the initial number of DNA double-strand breaks induced per Gy and per DNA unit (200 Mbp). Radio-induced apoptosis at 1, 2 and 8 Gy was measured by flow cytometry using annexin V/propidium iodide. Radiation-induced apoptosis increased in order to radiation dose and data fitted to a semi logarithmic mathematical model. A positive correlation was found among radio-induced apoptosis values at different radiation doses: 1, 2 and 8 Gy (p < 0.0001 in all cases). Mean DSB/Gy/DNA unit obtained was 1.70 ± 0.83 (range 0.63-4.08; median, 1.46). A statistically significant inverse correlation was found between initial damage to DNA and radio-induced apoptosis at 1 Gy (p = 0.034). A trend toward 2 Gy (p = 0.057) and 8 Gy (p = 0.067) was observed after 24 hours of incubation. An inverse association was observed for the first time between these variables, both considered as predictive factors to radiation toxicity

NASA Science4Girls: Engaging Girls in STEM at Their Local Library

Science.gov (United States)

Meinke, B.; Smith, D.; Bleacher, L.; Hauck, K.; Soeffing, C.; NASA SMD EPO Community

2014-07-01

The NASA Science Mission Directorate (SMD) Science Education and Public Outreach Forums coordinate the participation of SMD education and public outreach (EPO) programs in Women's History Month through the NASA Science4Girls and Their Families initiative. The initiative partners NASA science education programs with public libraries to provide NASA-themed hands-on education activities for girls and their families. The initiative has expanded from the successful 2012 Astro4Girls pilot to engage girls in all four NASA science discipline areas, which broadens the impact of the pilot by enabling audiences to experience the full range of NASA science topics and the different career skills each requires. The events focus on engaging underserved and underrepresented audiences in Science, Technology, Engineering, and Mathematics (STEM) via use of research-based best practices, collaborations with libraries, partnerships with local and national organizations, and remote engagement of audiences.

External event Probabilistic Risk Assessment for the High Flux Isotope Reactor (HFIR)

International Nuclear Information System (INIS)

Flanagan, G.F.; Johnson, D.H.; Buttemer, D.; Perla, H.F.; Chien, S.H.

1989-01-01

The High Flux Isotope Reactor (HFIR) is a high performance isotope production and research reactor which has been in operation at Oak Ridge National Laboratory (ORNL) since 1965. In late 1986 the reactor was shut down as a result of discovery of unexpected neutron embrittlement of the reactor vessel. In January of 1988 a level 1 Probabilistic Risk Assessment (PRA) (excluding external events) was published as part of the response to the many reviews that followed the shutdown and for use by ORNL to prioritize action items intended to upgrade the safety of the reactor. A conservative estimate of the core damage frequency initiated by internal events for HFIR was 3.11 x 10 -4 . In June 1989 a draft external events initiated PRA was published. The dominant contributions from external events came from seismic, wind, and fires. The overall external event contribution to core damage frequency is about 50% of the internal event initiated contribution and is dominated by seismic events

Synchronous inhibitory potentials precede seizure-like events in acute models of focal limbic seizures.

Science.gov (United States)

Uva, Laura; Breschi, Gian Luca; Gnatkovsky, Vadym; Taverna, Stefano; de Curtis, Marco

2015-02-18

Interictal spikes in models of focal seizures and epilepsies are sustained by the synchronous activation of glutamatergic and GABAergic networks. The nature of population spikes associated with seizure initiation (pre-ictal spikes; PSs) is still undetermined. We analyzed the networks involved in the generation of both interictal and PSs in acute models of limbic cortex ictogenesis induced by pharmacological manipulations. Simultaneous extracellular and intracellular recordings from both principal cells and interneurons were performed in the medial entorhinal cortex of the in vitro isolated guinea pig brain during focal interictal and ictal discharges induced in the limbic network by intracortical and brief arterial infusions of either bicuculline methiodide (BMI) or 4-aminopyridine (4AP). Local application of BMI in the entorhinal cortex did not induce seizure-like events (SLEs), but did generate periodic interictal spikes sensitive to the glutamatergic non-NMDA receptor antagonist DNQX. Unlike local applications, arterial perfusion of either BMI or 4AP induced focal limbic SLEs. PSs just ahead of SLE were associated with hyperpolarizing potentials coupled with a complete blockade of firing in principal cells and burst discharges in putative interneurons. Interictal population spikes recorded from principal neurons between two SLEs correlated with a depolarizing potential. We demonstrate in two models of acute limbic SLE that PS events are different from interictal spikes and are sustained by synchronous activation of inhibitory networks. Our findings support a prominent role of synchronous network inhibition in the initiation of a focal seizure. Copyright © 2015 the authors 0270-6474/15/353048-08$15.00/0.

The effectiveness of the cardiovascular disease prevention programme 'KardioPro' initiated by a German sickness fund: a time-to-event analysis of routine data.

Directory of Open Access Journals (Sweden)

Sabine Witt

Full Text Available Cardiovascular disease is the leading cause of morbidity and mortality in the developed world. To reduce this burden of disease, a German sickness fund ('Siemens-Betriebskrankenkasse', SBK initiated the prevention programme 'KardioPro' including primary (risk factor reduction and secondary (screening prevention and guideline-based treatment. The aim of this study was to assess the effectiveness of 'KardioPro' as it is implemented in the real world.The study is based on sickness fund routine data. The control group was selected from non-participants via propensity score matching. Study analysis was based on time-to-event analysis via Cox proportional hazards regression with the endpoint 'all-cause mortality, acute myocardial infarction (MI and ischemic stroke (1', 'all-cause mortality (2' and 'non-fatal acute MI and ischemic stroke (3'.A total of 26,202 insurants were included, 13,101 participants and 13,101 control subjects. 'KardioPro' enrollment was associated with risk reductions of 23.5% (95% confidence interval (CI 13.0-32.7% (1, 41.7% (95% CI 30.2-51.2% (2 and 3.5% (hazard ratio 0.965, 95% CI 0.811-1.148 (3. This corresponds to an absolute risk reduction of 0.29% (1, 0.31% (2 and 0.03% (3 per year.The prevention programme initiated by a German statutory sickness fund appears to be effective with regard to all-cause mortality. The non-significant reduction in non-fatal events might result from a shift from fatal to non-fatal events.

Final Report: Multi-State Sharing Initiative

Energy Technology Data Exchange (ETDEWEB)

Begoli, Edmon [ORNL; Boehmann, Brant [ORNL; DeNap, Frank A [ORNL

2012-04-01

In 2003 a joint effort between the U.S. Department of Homeland Security (DHS) and the U.S. Department of Justice created state and metropolitan intelligence fusion centers. These fusion centers were an effort to share law enforcement, disaster, and terrorism related information and intelligence between state and local jurisdictions and to share terrorism related intelligence between state and local law enforcement agencies and various federal entities. In 2006, DHS commissioned the Oak Ridge National Laboratory to establish and manage a groundbreaking program to assist local, state, and tribal leaders in developing the tools and methods required to anticipate and forestall terrorist events and to enhance disaster response. This program, called the Southeast Region Research Initiative (SERRI), combines science and technology with validated operational approaches to address regionally unique requirements and suggest regional solutions with the potential for national application. In 2009, SERRI sponsored the Multistate Sharing Initiative (MSSI) to assist state and metropolitan intelligence fusion centers with sharing information related to a wider variety of state interests than just terrorism. While these fusion centers have been effective at sharing data across organizations within their respective jurisdictions, their organizational structure makes bilateral communication with federal entities convenient and also allows information to be further disbursed to other local entities when appropriate. The MSSI-developed Suspicious Activity Report (SAR) sharing system allows state-to-state sharing of non-terrorism-related law enforcement and disaster information. Currently, the MSSI SAR system is deployed in Alabama, Kentucky, Tennessee, and South Carolina. About 1 year after implementation, cognizant fusion center personnel from each state were contacted to ascertain the status of their MSSI SAR systems. The overwhelming response from these individuals was that the MSSI

Obsidian hydration dating of volcanic events

Science.gov (United States)

Friedman, I.; Obradovich, J.

1981-01-01

Obsidian hydration dating of volcanic events had been compared with ages of the same events determined by the 14C and KAr methods at several localities. The localities, ranging in age from 1200 to over 1 million yr, include Newberry Craters, Oregon; Coso Hot Springs, California; Salton Sea, California; Yellowstone National Park, Wyoming; and Mineral Range, Utah. In most cases the agreement is quite good. A number of factors including volcanic glass composition and exposuretemperature history must be known in order to relate hydration thickness to age. The effect of composition can be determined from chemical analysis or the refractive index of the glass. Exposure-temperature history requires a number of considerations enumerated in this paper. ?? 1981.

Expanding the Universe of "Astronomy on Tap" Public Outreach Events

Science.gov (United States)

Rice, Emily L.; Levine, Brian; Livermore, Rachael C.; Silverman, Jeffrey M.; LaMassa, Stephanie M.; Tyndall, Amy; Muna, Demitri; Garofali, Kristen; Morris, Brett; Byler, Nell; Fyhrie, Adalyn; Rehnberg, Morgan; Hart, Quyen N.; Connelly, Jennifer L.; Silvia, Devin W.; Morrison, Sarah J.; Agarwal, Bhaskar; Tremblay, Grant; Schwamb, Megan E.

2016-01-01

Astronomy on Tap (AoT, astronomyontap.org) is free public outreach event featuring engaging science presentations in bars, often combined with music, games, and prizes, to encourage a fun, interactive atmosphere. AoT events feature several short astronomy-related presentations primarily by local professional scientists, but also by visiting scientists, students, educators, amatuer astronomers, writers, and artists. Events are held in social venues (bars, coffee shops, art galleries, etc.) in order to bring science directly to the public in a relaxed, informal atmosphere. With this we hope to engage a more diverse audience than typical lectures at academic and cultural institutions and to develop enthusiasm for science among voting, tax-paying adults. The flexible format and content of an AoT event is easy to adapt and expand based on the priorities, resources, and interests of local organizers. The social nature of AoT events provides important professional development and networking opportunities in science communication. Since the first New York City event in April 2013, Astronomy on Tap has expanded to more than ten cities globally, including monthly events in NYC, Austin, Seattle, and Tucson; semi-regular events in Columbus, New Haven, Santiago, Toronto, and Denver; occasional (so far) events in Rochester (NY), Baltimore, Lansing, and Washington, DC; and one-off events in Chicago and Taipei. Several venues regularly attract audiences of over 200 people. We have received media coverage online, in print, and occasionally even on radio and television. In this poster we describe the overarching goals and characteristics of AoT events, distinct adaptations of various locations, resources we have developed, and the methods we use to coordinate among the worldwide local organizers.

Report of Committee for JAEA Internationalization Initiative. Focusing on the activities of local teams

International Nuclear Information System (INIS)

2015-10-01

The 'Committee for JAEA Internationalization Initiative' was established in 2010 with the view to discuss the policy and improvement plans for JAEA's achievement of an international center of excellence (ICOE), which include improving the environment to accept foreign researchers, etc. The existing issues to be solved in the effort for ICOE and recommendations for the solutions, which were discussed in the committee, and challenges in developing human resources with a global mindset were written in the report summarizing the activities conducted in the following two years. This report was compiled focusing on the efforts in respective sites made during a period of two years from 2013 to 2014 by the local teams that were set up in accordance with the situation of the R and D centers hosting a number of foreign researchers, etc. based on the above-mentioned recommendations. (author)

Designing Technology for Active Spectator Experiences at Sporting Events

DEFF Research Database (Denmark)

Veerasawmy, Rune; Ludvigsen, Martin

2010-01-01

This paper explores the active spectator experience at sporting events, by presenting and reflecting upon a design experiment carried out at a number of football1 events. The initial hypothesis of the design process, leading to the design experiment has been that the spectator experience is not m......This paper explores the active spectator experience at sporting events, by presenting and reflecting upon a design experiment carried out at a number of football1 events. The initial hypothesis of the design process, leading to the design experiment has been that the spectator experience...... is not merely an experience of receiving and consuming entertainment. It is also heavily reliant on the active participation of the spectator in creating the atmosphere of the entire event. The BannerBattle experiment provides interactive technology in sport arenas with a form of interaction based on existing...

The ATLAS Event Service: A New Approach to Event Processing

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00070566; De, Kaushik; Guan, Wen; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Tsulaia, Vakhtang; van Gemmeren, Peter; Wenaus, Torre

2015-01-01

The ATLAS Event Service (ES) implements a new fine grained approach to HEP event processing, designed to be agile and efficient in exploiting transient, short-lived resources such as HPC hole-filling, spot market commercial clouds, and volunteer computing. Input and output control and data flows, bookkeeping, monitoring, and data storage are all managed at the event level in an implementation capable of supporting ATLAS-scale distributed processing throughputs (about 4M CPU-hours/day). Input data flows utilize remote data repositories with no data locality or pre­staging requirements, minimizing the use of costly storage in favor of strongly leveraging powerful networks. Object stores provide a highly scalable means of remotely storing the quasi-continuous, fine grained outputs that give ES based applications a very light data footprint on a processing resource, and ensure negligible losses should the resource suddenly vanish. We will describe the motivations for the ES system, its unique features and capabi...

BACODINE/3rd Interplanetary Network burst localization

International Nuclear Information System (INIS)

Hurley, K.; Barthelmy, S.; Butterworth, P.; Cline, T.; Sommer, M.; Boer, M.; Niel, M.; Kouveliotou, C.; Fishman, G.; Meegan, C.

1996-01-01

Even with only two widely separated spacecraft (Ulysses and GRO), 3rd Interplanetary Network (IPN) localizations can reduce the areas of BATSE error circles by two orders of magnitude. Therefore it is useful to disseminate them as quickly as possible following BATSE bursts. We have implemented a system which transmits the light curves of BACODINE/BATSE bursts directly by e-mail to UC Berkeley immediately after detection. An automatic e-mail parser at Berkeley watches for these notices, determines the Ulysses crossing time window, and initiates a search for the burst data on the JPL computer as they are received. In ideal cases, it is possible to retrieve the Ulysses data within a few hours of a burst, generate an annulus of arrival directions, and e-mail it out to the astronomical community by local nightfall. Human operators remain in this loop, but we are developing a fully automated routine which should remove them, at least for intense events, and reduce turn-around times to an absolute minimum. We explain the current operations, the data types used, and the speed/accuracy tradeoffs

Leveraging Long-term Seismic Catalogs for Automated Real-time Event Classification

Science.gov (United States)

Linville, L.; Draelos, T.; Pankow, K. L.; Young, C. J.; Alvarez, S.

2017-12-01

We investigate the use of labeled event types available through reviewed seismic catalogs to produce automated event labels on new incoming data from the crustal region spanned by the cataloged events. Using events cataloged by the University of Utah Seismograph Stations between October, 2012 and June, 2017, we calculate the spectrogram for a time window that spans the duration of each event as seen on individual stations, resulting in 110k event spectrograms (50% local earthquakes examples, 50% quarry blasts examples). Using 80% of the randomized example events ( 90k), a classifier is trained to distinguish between local earthquakes and quarry blasts. We explore variations of deep learning classifiers, incorporating elements of convolutional and recurrent neural networks. Using a single-layer Long Short Term Memory recurrent neural network, we achieve 92% accuracy on the classification task on the remaining 20K test examples. Leveraging the decisions from a group of stations that detected the same event by using the median of all classifications in the group increases the model accuracy to 96%. Additional data with equivalent processing from 500 more recently cataloged events (July, 2017), achieves the same accuracy as our test data on both single-station examples and multi-station medians, suggesting that the model can maintain accurate and stable classification rates on real-time automated events local to the University of Utah Seismograph Stations, with potentially minimal levels of re-training through time.

APPROXIMATION OF THE TIME TO INITIATE THE EVACUATION

Directory of Open Access Journals (Sweden)

Jiří POKORNÝ

2016-06-01

Full Text Available One of the basic prerequisites for securing the safety of people at large group events is to ensure their evacuation in case of emergencies. This article deals with the approximations of time to initiate the evacuation of persons in case of a fire at large group events organized in outdoor spaces. The solution is based on the principles of determining the period to initiate the evacuation of persons in terms of international ISO standards. Considering the specificities of the given outdoor space and possible related security measures, the article recommends the relevant sufficient amount of time to initiate an evacuation.

Robust Initial Wetness Condition Framework of an Event-Based Rainfall–Runoff Model Using Remotely Sensed Soil Moisture

Directory of Open Access Journals (Sweden)

Wooyeon Sunwoo

2017-01-01

Full Text Available Runoff prediction in limited-data areas is vital for hydrological applications, such as the design of infrastructure and flood defenses, runoff forecasting, and water management. Rainfall–runoff models may be useful for simulation of runoff generation, particularly event-based models, which offer a practical modeling scheme because of their simplicity. However, there is a need to reduce the uncertainties related to the estimation of the initial wetness condition (IWC prior to a rainfall event. Soil moisture is one of the most important variables in rainfall–runoff modeling, and remotely sensed soil moisture is recognized as an effective way to improve the accuracy of runoff prediction. In this study, the IWC was evaluated based on remotely sensed soil moisture by using the Soil Conservation Service-Curve Number (SCS-CN method, which is one of the representative event-based models used for reducing the uncertainty of runoff prediction. Four proxy variables for the IWC were determined from the measurements of total rainfall depth (API5, ground-based soil moisture (SSMinsitu, remotely sensed surface soil moisture (SSM, and soil water index (SWI provided by the advanced scatterometer (ASCAT. To obtain a robust IWC framework, this study consists of two main parts: the validation of remotely sensed soil moisture, and the evaluation of runoff prediction using four proxy variables with a set of rainfall–runoff events in the East Asian monsoon region. The results showed an acceptable agreement between remotely sensed soil moisture (SSM and SWI and ground based soil moisture data (SSMinsitu. In the proxy variable analysis, the SWI indicated the optimal value among the proposed proxy variables. In the runoff prediction analysis considering various infiltration conditions, the SSM and SWI proxy variables significantly reduced the runoff prediction error as compared with API5 by 60% and 66%, respectively. Moreover, the proposed IWC framework with

Seasonal Accumulation and Depletion of Local Sediment Stores of Four Headwater Catchments

Directory of Open Access Journals (Sweden)

Sarah E. Martin

2014-07-01

Full Text Available Seasonal turbidity patterns and event-level hysteresis analysis of turbidity verses discharge in four 1 km2 headwater catchments in California’s Sierra Nevada indicate localized in-channel sediment sources and seasonal accumulation-depletion patterns of stream sediments. Turbidity signals were analyzed for three years in order to look at the relationships between seasonal turbidity trends, event turbidity patterns, and precipitation type to stream sediment production and transport. Seasonal patterns showed more turbidity events associated with fall and early to mid- winter events than with peak snow-melt. No significant turbidity patterns emerged for periods of snow melt vs. rain. Single event hysteresis loops showed clockwise patterns were dominant suggesting local sediment sources. In successive discharge events, the largest turbidity spike was often associated with the first but not necessarily the largest discharge event-indicating seasonal depletion of local sediment stores. In multi-peaked discharge events, hysteresis loops shifted from clockwise to linear or random patterns suggesting that localized sediment stores are being used up and sufficient flow energy must be reached to start entraining the more consolidated bank/bed sediment or that dominant sediment sources may be shifting to less localized areas such as hill slopes. A conceptual model with phases of accumulation and transport is proposed.

Accident analyses in nuclear power plants following external initiating events and in the shutdown state. Final report; Unfallanalysen in Kernkraftwerken nach anlagenexternen ausloesenden Ereignissen und im Nichtleistungsbetrieb. Abschlussbericht

Energy Technology Data Exchange (ETDEWEB)

Loeffler, Horst; Kowalik, Michael; Mildenberger, Oliver; Hage, Michael

2016-06-15

The work which is documented here provides the methodological basis for improvement of the state of knowledge for accident sequences after plant external initiating events and for accident sequences which begin in the shutdown state. The analyses have been done for a PWR and for a BWR reference plant. The work has been supported by the German federal ministry BMUB under the label 3612R01361. Top objectives of the work are: - Identify relevant event sequences in order to define characteristic initial and boundary conditions - Perform accident analysis of selected sequences - Evaluate the relevance of accident sequences in a qualitative way The accident analysis is performed with the code MELCOR 1.8.6. The applied input data set has been significantly improved compared to previous analyses. The event tree method which is established in PSA level 2 has been applied for creating a structure for a unified summarization and evaluation of the results from the accident analyses. The computer code EVNTRE has been applied for this purpose. In contrast to a PSA level 2, the branching probabilities of the event tree have not been determined with the usual accuracy, but they are given in an approximate way only. For the PWR, the analyses show a considerable protective effect of the containment also in the case of beyond design events. For the BWR, there is a rather high probability for containment failure under core melt impact, but nevertheless the release of radionuclides into the environment is very limited because of plant internal retention mechanisms. This report concludes with remarks about existing knowledge gaps and with regard to core melt sequences, and about possible improvements of the plant safety.

Probability model for worst case solar proton event fluences

International Nuclear Information System (INIS)

Xapsos, M.A.; Summers, G.P.; Barth, J.L.; Stassinopoulos, E.G.; Burke, E.A.

1999-01-01

The effects that solar proton events have on microelectronics and solar arrays are important considerations for spacecraft in geostationary orbits, polar orbits and on interplanetary missions. A predictive model of worst case solar proton event fluences is presented. It allows the expected worst case event fluence to be calculated for a given confidence level and for periods of time corresponding to space missions. The proton energy range is from >1 to >300 MeV, so that the model is useful for a variety of radiation effects applications. For each proton energy threshold, the maximum entropy principle is used to select the initial distribution of solar proton event fluences. This turns out to be a truncated power law, i.e., a power law for smaller event fluences that smoothly approaches zero at a maximum fluence. The strong agreement of the distribution with satellite data for the last three solar cycles indicates this description captures the essential features of a solar proton event fluence distribution. Extreme value theory is then applied to the initial distribution of events to obtain the model of worst case fluences

PRELIMINARY SELECTION OF MGR DESIGN BASIS EVENTS

International Nuclear Information System (INIS)

Kappes, J.A.

1999-01-01

The purpose of this analysis is to identify the preliminary design basis events (DBEs) for consideration in the design of the Monitored Geologic Repository (MGR). For external events and natural phenomena (e.g., earthquake), the objective is to identify those initiating events that the MGR will be designed to withstand. Design criteria will ensure that radiological release scenarios resulting from these initiating events are beyond design basis (i.e., have a scenario frequency less than once per million years). For internal (i.e., human-induced and random equipment failures) events, the objective is to identify credible event sequences that result in bounding radiological releases. These sequences will be used to establish the design basis criteria for MGR structures, systems, and components (SSCs) design basis criteria in order to prevent or mitigate radiological releases. The safety strategy presented in this analysis for preventing or mitigating DBEs is based on the preclosure safety strategy outlined in ''Strategy to Mitigate Preclosure Offsite Exposure'' (CRWMS M andO 1998f). DBE analysis is necessary to provide feedback and requirements to the design process, and also to demonstrate compliance with proposed 10 CFR 63 (Dyer 1999b) requirements. DBE analysis is also required to identify and classify the SSCs that are important to safety (ITS)

Reconstructing the Initial Density Field of the Local Universe: Methods and Tests with Mock Catalogs

Science.gov (United States)

Wang, Huiyuan; Mo, H. J.; Yang, Xiaohu; van den Bosch, Frank C.

2013-07-01

Our research objective in this paper is to reconstruct an initial linear density field, which follows the multivariate Gaussian distribution with variances given by the linear power spectrum of the current cold dark matter model and evolves through gravitational instabilities to the present-day density field in the local universe. For this purpose, we develop a Hamiltonian Markov Chain Monte Carlo method to obtain the linear density field from a posterior probability function that consists of two components: a prior of a Gaussian density field with a given linear spectrum and a likelihood term that is given by the current density field. The present-day density field can be reconstructed from galaxy groups using the method developed in Wang et al. Using a realistic mock Sloan Digital Sky Survey DR7, obtained by populating dark matter halos in the Millennium simulation (MS) with galaxies, we show that our method can effectively and accurately recover both the amplitudes and phases of the initial, linear density field. To examine the accuracy of our method, we use N-body simulations to evolve these reconstructed initial conditions to the present day. The resimulated density field thus obtained accurately matches the original density field of the MS in the density range 0.3 \\lesssim \\rho /\\bar{\\rho } \\lesssim 20 without any significant bias. In particular, the Fourier phases of the resimulated density fields are tightly correlated with those of the original simulation down to a scale corresponding to a wavenumber of ~1 h Mpc-1, much smaller than the translinear scale, which corresponds to a wavenumber of ~0.15 h Mpc-1.

An Event-Based Approach to Distributed Diagnosis of Continuous Systems

Science.gov (United States)

Daigle, Matthew; Roychoudhurry, Indranil; Biswas, Gautam; Koutsoukos, Xenofon

2010-01-01

Distributed fault diagnosis solutions are becoming necessary due to the complexity of modern engineering systems, and the advent of smart sensors and computing elements. This paper presents a novel event-based approach for distributed diagnosis of abrupt parametric faults in continuous systems, based on a qualitative abstraction of measurement deviations from the nominal behavior. We systematically derive dynamic fault signatures expressed as event-based fault models. We develop a distributed diagnoser design algorithm that uses these models for designing local event-based diagnosers based on global diagnosability analysis. The local diagnosers each generate globally correct diagnosis results locally, without a centralized coordinator, and by communicating a minimal number of measurements between themselves. The proposed approach is applied to a multi-tank system, and results demonstrate a marked improvement in scalability compared to a centralized approach.

Probabilistic assessment of fire related events in CWPH (Pilot study)

International Nuclear Information System (INIS)

Chatterjee, D.; Maity, S.C.; Guptan, Rajee; Mohan, Nalini; Ghadge, S.G.; Bajaj, S.S.

2006-01-01

As a part of Fire PSA for KAPS, a pilot study has been taken up identifying CWPH as the important zone vulnerable to fire. As the CWPH houses pumps belonging to all important cooling (APWC, FFW, NAHPPW, NALPW, etc.) of both the units, a single fire leads to failure of multiple safety/safety support system cooling affecting the safety of the plant. The objective of this study is as follows: Familiarising with the various published Fire-PSA study, comparing and finalisation of the computer code amongst various codes available with DAE, identifying and sequencing different activities involved for carrying out Fire PSA, i.e. Zoning and Sub-Zoning of Fire Source Area, Fire vulnerability of System and Component surrounding Fire Source, etc., finalization of report format and documentation. Computer Code FDS is used to carry out Fire Hazard Analysis. FDS is the latest state-of the-art software package extensively used for Fire Hazard Analysis. It develops a 3D scenario for any given fire giving credit to actual physical location of fire load and ventilation. It gives the time dependent of any fire in a specific zone crediting the time required by operator to take necessary preventive action which helps in quantifying the probability of error for any particular operator's for PSA study. To identify the most vulnerable sub-zone in CWPH, a walk down was organized and physical location of each load; their separation, fire barrier, ventilator in the room, arrangement of fire protection/fighting system, localized operator's room were reviewed. Fire in the middle diesel tank with pump is considered as initiating event in the sub-zone of CWPH. The Event Tree for this initiating event for CWPH was developed. Event Tree end states are identified as large fire i.e. fire which is failed to be detected by both means, i.e. early and late and failure in fighting by both means i.e. early and late. (author)

Integrated landscape initiatives in Europe

DEFF Research Database (Denmark)

García-Martín, María; Bieling, Claudia; Hart, Abigail

2016-01-01

Landscapes are linked to human well-being in a multitude of ways, some of which are challenged by global market forces and traditional management approaches. In response to this situation there has been a rise in local initiatives to sustain the values of landscape. The aim of this paper is to pr......Landscapes are linked to human well-being in a multitude of ways, some of which are challenged by global market forces and traditional management approaches. In response to this situation there has been a rise in local initiatives to sustain the values of landscape. The aim of this paper...... searches and canvassing of European umbrella organisations; followed by an online survey of representatives from the identified initiatives (n??=??71). Our results show that the most relevant characteristics of integrated landscape initiatives in Europe are: a holistic approach to landscape management...

Teachers’ perceptions of their own initiative: Collective initiative vs. personal initiative

Directory of Open Access Journals (Sweden)

Džinović Vladimir

2013-01-01

Full Text Available Current trends in education demand from teachers to exhibit proactive behaviour and assume responsibility for the implementation of changes in school practice. In that sense, it is important to study how teachers perceive their own initiative and to gain insight into the activities where such initiative is demonstrated. This study has been conceived as a mixed-methods research. The qualitative study implied forming four focus groups with subject teachers and class teachers (N=38, while the quantitative study entailed surveying 1441 teachers in forty primary schools in Serbia using the questionnaire constructed based on qualitative data. Data from focus groups were processed by qualitative thematic analysis, while the questionnaire data were processed by principal component analysis and univariate analysis of variance. The findings of the study have shown that teachers mostly demonstrate initiative through co­operative activities that include planning of joint teaching as well as conducting joint projects within school and with the local community actors. Teachers are least ready to demonstrate personal initiative and the initiative aimed at accomplishing considerable changes in school work. The concluding part includes the recommendations for encouraging teachers’ personal initiative and building organizational culture that would support such initiative. [Projekat Ministarstva nauke Republike Srbije, br. br. 47008: Unapređivanje kvaliteta i dostupnosti obrazovanja u procesima modernizacije Srbije i br. 179034: Od podsticanja inicijative, saradnje i stvaralaštva u obrazovanju do novih uloga i identiteta u društvu

PESP Landscaping Initiative

Science.gov (United States)

Landscaping practices can positively or negatively affect local environments and human health. The Landscaping Initiative seeks to enhance benefits of landscaping while reducing need for pesticides, fertilizers, etc., by working with partners.

External events analysis for the Savannah River Site K reactor

International Nuclear Information System (INIS)

Brandyberry, M.D.; Wingo, H.E.

1990-01-01

The probabilistic external events analysis performed for the Savannah River Site K-reactor PRA considered many different events which are generally perceived to be ''external'' to the reactor and its systems, such as fires, floods, seismic events, and transportation accidents (as well as many others). Events which have been shown to be significant contributors to risk include seismic events, tornados, a crane failure scenario, fires and dam failures. The total contribution to the core melt frequency from external initiators has been found to be 2.2 x 10 -4 per year, from which seismic events are the major contributor (1.2 x 10 -4 per year). Fire initiated events contribute 1.4 x 10 -7 per year, tornados 5.8 x 10 -7 per year, dam failures 1.5 x 10 -6 per year and the crane failure scenario less than 10 -4 per year to the core melt frequency. 8 refs., 3 figs., 5 tabs

Field investigation of mining-induced seismicity on local geohydrology

International Nuclear Information System (INIS)

Hsiung, S.M.; Chowdhury, A.H.; Philip, J.; Blake, W.

1993-01-01

Hydraulic response of the rock mass due to earthquakes is one of the concerns in the assessment of the long-term performance of a repository. Studies performed by other researchers indicated no systematic difference between natural earthquakes and mining-induced seismic events. The purpose of this field study at the Lucky Friday Mine is intended to obtain a better understanding regarding the local geohydrologic changes due to mining-induced seismicity and to evaluate analytical methods for simulation of these changes. Three saturated zones with faults and vein features were packed-off along a borehole drilled at approximately 20 degrees downward in a southerly direction from a depth about 1,737 m (5,700 ft) below surface for water pressure monitoring. The response of water pressure change to mine seismicity is found to be more pronounced in Zone 3, which contains the Lucky Friday Main Vein, than Zone 2, with the South Control Fault, and Zone 1, with the associated fractures parallel to the South Control Fault. The maximum observed pressure increase in Zone 3 was about 1.53 x 10 -2 MPa (2.22 psi) due to a seismic event of Richter drops in Zone 1 resulting from a number of seismic events are suspected to be related to slips along the associated fractures of the South Control Fault, or the South Control Fault itself, which initiated the seismic events. Water pressure increase in Zone 3 was found to be a function of event magnitude and distance

Developing future precipitation events from historic events: An Amsterdam case study.

Science.gov (United States)

Manola, Iris; van den Hurk, Bart; de Moel, Hans; Aerts, Jeroen

2016-04-01

Due to climate change, the frequency and intensity of extreme precipitation events is expected to increase. It is therefore of high importance to develop climate change scenarios tailored towards the local and regional needs of policy makers in order to develop efficient adaptation strategies to reduce the risks from extreme weather events. Current approaches to tailor climate scenarios are often not well adopted in hazard management, since average changes in climate are not a main concern to policy makers, and tailoring climate scenarios to simulate future extremes can be complex. Therefore, a new concept has been introduced recently that uses known historic extreme events as a basis, and modifies the observed data for these events so that the outcome shows how the same event would occur in a warmer climate. This concept is introduced as 'Future Weather', and appeals to the experience of stakeholders and users. This research presents a novel method of projecting a future extreme precipitation event, based on a historic event. The selected precipitation event took place over the broader area of Amsterdam, the Netherlands in the summer of 2014, which resulted in blocked highways, disruption of air transportation, flooded buildings and public facilities. An analysis of rain monitoring stations showed that an event of such intensity has a 5 to 15 years return period. The method of projecting a future event follows a non-linear delta transformation that is applied directly on the observed event assuming a warmer climate to produce an "up-scaled" future precipitation event. The delta transformation is based on the observed behaviour of the precipitation intensity as a function of the dew point temperature during summers. The outcome is then compared to a benchmark method using the HARMONIE numerical weather prediction model, where the boundary conditions of the event from the Ensemble Prediction System of ECMWF (ENS) are perturbed to indicate a warmer climate. The two

24 CFR 125.201 - Administrative Enforcement Initiative.

Science.gov (United States)

2010-04-01

... Initiative. 125.201 Section 125.201 Housing and Urban Development Regulations Relating to Housing and Urban... FAIR HOUSING FAIR HOUSING INITIATIVES PROGRAM § 125.201 Administrative Enforcement Initiative. The Administrative Enforcement Initiative provides funding to State and local fair housing agencies administering...

Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides.

Science.gov (United States)

Egan, Jan B; Shi, Chang-Xin; Tembe, Waibhav; Christoforides, Alexis; Kurdoglu, Ahmet; Sinari, Shripad; Middha, Sumit; Asmann, Yan; Schmidt, Jessica; Braggio, Esteban; Keats, Jonathan J; Fonseca, Rafael; Bergsagel, P Leif; Craig, David W; Carpten, John D; Stewart, A Keith

2012-08-02

The longitudinal evolution of a myeloma genome from diagnosis to plasma cell leukemia has not previously been reported. We used whole-genome sequencing (WGS) on 4 purified tumor samples and patient germline DNA drawn over a 5-year period in a t(4;14) multiple myeloma patient. Tumor samples were acquired at diagnosis, first relapse, second relapse, and end-stage secondary plasma cell leukemia (sPCL). In addition to the t(4;14), all tumor time points also shared 10 common single-nucleotide variants (SNVs) on WGS comprising shared initiating events. Interestingly, we observed genomic sequence variants that waxed and waned with time in progressive tumors, suggesting the presence of multiple independent, yet related, clones at diagnosis that rose and fell in dominance. Five newly acquired SNVs, including truncating mutations of RB1 and ZKSCAN3, were observed only in the final sPCL sample suggesting leukemic transformation events. This longitudinal WGS characterization of the natural history of a high-risk myeloma patient demonstrated tumor heterogeneity at diagnosis with shifting dominance of tumor clones over time and has also identified potential mutations contributing to myelomagenesis as well as transformation from myeloma to overt extramedullary disease such as sPCL.

Event texture search for critical fluctuations in Pb + Pb collisions

CERN Document Server

Kopytine, M L; Bearden, I G; Bøggild, H; Boissevain, J G; Conin, L; Dodd, J; Erazmus, B; Esumi, S C; Fabjan, Christian Wolfgang; Ferenc, D; Fields, D E; Franz, A; Gaardhøje, J J; Hansen, A G; Hansen, O; Hardtke, D; van Hecke, H; Holzer, E B; Humanic, T J; Hummel, P; Jacak, B V; Jayanti, R; Kaimi, K; Kaneta, M; Kohama, T; Kopytine, M L; Leltchouk, M; Ljubicic, A; Lörstad, B; Maeda, N; Martin, L; Medvedev, A; Murray, M; Ohnishi, H; Paic, G; Pandey, S U; Piuz, François; Pluta, J; Polychronakos, V; Potekhin, M V; Poulard, G; Reichhold, D M; Sakaguchi, A; Schmidt-Sørensen, J; Simon-Gillo, J; Sondheim, W E; Sugitate, T; Sullivan, J P; Sumi, Y; Willis, W J; Wolf, K L; Xu, N; Zachary, D S

2002-01-01

NA44 uses a 512 channel Si pad array covering $1.5 <\\eta < 3.3$ to study charged hadron production in 158 A GeV Pb+Pb collisions at the CERN SPS. We apply a multiresolution analysis, based on a Discrete Wavelet Transformation, to probe the texture of particle distributions event-by-event, by simultaneous localization of features in space and scale. Scanning a broad range of multiplicities, we look for a possible critical behaviour in the power spectra of local density fluctuations. The data are compared with detailed simulations of detector response, using heavy ion event generators, and with a reference sample created via event mixing. An upper limit is set on the probability and magnitude of dynamical fluctuations.

Event Texture Search for Phase Transitions in Pb+Pb Collisions

CERN Document Server

Bearden, I G; Bøggild, H; Boissevain, J; Conin, L; Dood, J; Erazmus, B; Esumi, S; Fabjan, B W; Ferenc, D; Fields, D E; Franz, A; Gaardhodje, J J; Hansen, A G; Hansen, O; Hardtke, D; Hecke, V H; Holzer, E B; Humanic, T J; Hummel, P; Jacak, V B; Jayanti, R; Kaimi, K; Kaneta, M; Kohama, T; Kopytine, M L; Letchouk, M; Ljubicic, A; Lörstad, B; Maeda, N; Matin, L; Medvedev, A; Murray, M; Ohnishi, H; Paic, G; Pandey, S U; Piuz, François; Pluta, J; Polychronakos, V; Pothekin, M; Poulard, G; Reichhold, D; Sakaguchi, A; Schimdt-Sorensen, J; Simmon-Gillo, J; Sondheime, W; Sugitate, T; Sullivan, J P; Sumi, Y; Willis, W J; Wolf, K L; Xu, N; Zachary, D S

2002-01-01

NA44 uses a 512 channel Si pad array covering $1.5 <\\eta < 3.3$ to study charged hadron production in 158 A GeV Pb+Pb collisions at the CERN SPS. We apply a multiresolution analysis, based on a Discrete Wavelet Transformation, to probe the texture of particle distributions event-by-event, allowing simultaneous localization of features in space and scale. Scanning a broad range of multiplicities, we search for signals of clustering and of critical behavior in the power spectra of local density fluctuations. The data are compared with detailed simulations of detector response, using heavy ion event generators, and with a reference sample created via event mixing. An upper limit is set on the probability and magnitude of dynamical fluctuations.

Understanding Laterally Varying Path Effects on P/S Ratios and their Effectiveness for Event Discrimination at Local Distances

Science.gov (United States)

Pyle, M. L.; Walter, W. R.

2017-12-01

Discrimination between underground explosions and naturally occurring earthquakes is an important endeavor for global security and test-ban treaty monitoring, and ratios of seismic P to S-wave amplitudes at regional distances have proven to be an effective discriminant. The use of the P/S ratio is rooted in the idea that explosive sources should theoretically only generate compressional energy. While, in practice, shear energy is observed from explosions, generally when corrections are made for magnitude and distance, P/S ratios from explosions are higher than those from surrounding earthquakes. At local distances (chemical explosions at the Nevada National Security Site (NNSS) designed to improve our understanding and modeling capabilities of shear waves generated by explosions. Phase I consisted of 5 explosions in granite and Phase II will move to a contrasting dry alluvium geology. We apply a high-resolution 2D attenuation model to events near the NNSS to examine what effect path plays in local P/S ratios, and how well an earthquake-derived model can account for shallower explosion paths. The model incorporates both intrinsic attenuation and scattering effects and extends to 16 Hz, allowing us to make lateral path corrections and consider high-frequency ratios. Preliminary work suggests that while 2D path corrections modestly improve earthquake amplitude predictions, explosion amplitudes are not well matched, and so P/S ratios do not necessarily improve. Further work is needed to better understand the uses and limitation of 2D path corrections for local P/S ratios.

Numerical study of the effects of local atmospheric circulations on a pollution event over Beijing-Tianjin-Hebei, China.

Science.gov (United States)

Miao, Yucong; Liu, Shuhua; Zheng, Yijia; Wang, Shu; Chen, Bicheng; Zheng, Hui; Zhao, Jingchuan

2015-04-01

Currently, the Chinese central government is considering plans to build a trilateral economic sphere in the Bohai Bay area, including Beijing, Tianjin and Hebei (BTH), where haze pollution frequently occurs. To achieve sustainable development, it is necessary to understand the physical mechanism of the haze pollution there. Therefore, the pollutant transport mechanisms of a haze event over the BTH region from 23 to 24 September 2011 were studied using the Weather Research and Forecasting model and the FLEXible-PARTicle dispersion model to understand the effects of the local atmospheric circulations and atmospheric boundary layer structure. Results suggested that the penetration by sea-breeze could strengthen the vertical dispersion by lifting up the planetary boundary layer height (PBLH) and carry the local pollutants to the downstream areas; in the early night, two elevated pollution layers (EPLs) may be generated over the mountain areas: the pollutants in the upper EPL at the altitude of 2-2.5 km were favored to disperse by long-range transport, while the lower EPL at the altitude of 1 km may serve as a reservoir, and the pollutants there could be transported downward and contribute to the surface air pollution. The intensity of the sea-land and mountain-valley breeze circulations played an important role in the vertical transport and distribution of pollutants. It was also found that the diurnal evolution of the PBLH is important for the vertical dispersion of the pollutants, which is strongly affected by the local atmospheric circulations and the distribution of urban areas. Copyright © 2015. Published by Elsevier B.V.

Scenario evolution: Interaction between event tree construction and numerical analyses

International Nuclear Information System (INIS)

Barr, G.E.; Barnard, R.W.; Dockery, H.A.; Dunn, E.; MacIntyre, A.T.

1990-01-01

Construction of well-posed scenarios for the range of conditions possible at any proposed repository site is a critical first step to assessing total system performance. Event tree construction is the method that is being used to develop potential failure scenarios for the proposed nuclear waste repository at Yucca Mountain. An event tree begins with an initial event or condition. Subsequent events are listed in a sequence, leading eventually to release of radionuclides to the accessible environment. Ensuring the validity of the scenarios requires iteration between problems constructed using scenarios contained in the event tree sequence, experimental results, and numerical analyses. Details not adequately captured within the tree initially may become more apparent as a result of analyses. To illustrate this process, the authors discuss the iterations used to develop numerical analyses for PACE-90 (Performance Assessment Calculational Exercises) using basaltic igneous activity and human-intrusion event trees

77 FR 15647 - Special Local Regulation for Marine Events; Temporary Change of Dates for Recurring Marine Events...

Science.gov (United States)

2012-03-16

... typically comprise marine events include sailing regattas, power boat races, swim races and holiday parades... and responsibilities between the Federal Government and Indian tribes. Energy Effects We have analyzed... Affect Energy Supply, Distribution, or Use. We have determined that it is not a ``significant energy...

Localized deformation as a key precursor to initiation of intergranular stress corrosion cracking of austenitic stainless steels employed in nuclear power plants

International Nuclear Information System (INIS)

Karlsen, Wade; Diego, Gonzalo; Devrient, Bastian

2010-01-01

Cold-work has been associated with the occurrence of intergranular cracking of stainless steels employed in light water reactors. This study examined the deformation behavior of AISI 304, AISI 347 and a higher stacking fault energy model alloy subjected to bulk cold-work and (for 347) surface deformation. Deformation microstructures of the materials were examined and correlated with their particular mechanical response under different conditions of temperature, strain rate and degree of prior cold-work. Select slow-strain rate tensile tests in autoclaves enabled the role of local strain heterogeneity in crack initiation in pressurized water reactor environments to be considered. The high stacking fault energy material exhibited uniform strain hardening, even at sub-zero temperatures, while the commercial stainless steels showed significant heterogeneity in their strain response. Surface treatments introduced local cold-work, which had a clear effect on the surface roughness and hardness, and on near-surface residual stress profiles. Autoclave tests led to transgranular surface cracking for a circumferentially ground surface, and intergranular crack initiation for a polished surface.

RoboCup European Championship: Report of the Amsterdam 2000 event

NARCIS (Netherlands)

Groen, F.; van der Hoek, W.; Jonker, P.; Krose, B.; Spoelder, H.J.W.; Stramigioli, S.

2001-01-01

The local organizers of the RoboCup European Championship presents a brief, informal overview of this event with the aim to support organizers of future RoboCup events in the organization and coordination of such a rather complex tournament. The objective was to organize a low cost scientific event

The Advanced Photon Source event system

International Nuclear Information System (INIS)

Lenkszus, F.R.; Laird, R.

1995-01-01

The Advanced Photon Source, like many other facilities, requires a means of transmitting timing information to distributed control system 1/0 controllers. The APS event system provides the means of distributing medium resolution/accuracy timing events throughout the facility. It consists of VME event generators and event receivers which are interconnected with 10OMbit/sec fiber optic links at distances of up to 650m in either a star or a daisy chain configuration. The systems event throughput rate is 1OMevents/sec with a peak-to-peak timing jitter down to lOOns depending on the source of the event. It is integrated into the EPICS-based A.PS control system through record and device support. Event generators broadcast timing events over fiber optic links to event receivers which are programmed to decode specific events. Event generators generate events in response to external inputs, from internal programmable event sequence RAMS, and from VME bus writes. The event receivers can be programmed to generate both pulse and set/reset level outputs to synchronize hardware, and to generate interrupts to initiate EPICS record processing. In addition, each event receiver contains a time stamp counter which is used to provide synchronized time stamps to EPICS records

Preemptive warfarin dose reduction after initiation of sulfamethoxazole-trimethoprim or metronidazole.

Science.gov (United States)

Powers, Anna; Loesch, Erin B; Weiland, Anthony; Fioravanti, Nicole; Lucius, David

2017-07-01

To evaluate the utility of a preemptive warfarin dose reduction at the time of initiation of either sulfamethoxazole-trimethoprim or metronidazole, a retrospective chart review of patients who received an outpatient prescription for warfarin and either sulfamethoxazole-trimethoprim and/or metronidazole from July 1, 2011 to July 1, 2015 was conducted. Clinical outcomes compared Veterans who had a warfarin dose reduction and those who did not within 120 h (5 days) of antibiotic initiation. The primary outcome compared the pre-and post-antibiotic International Normalized Ratio (INR) of patients in the intervention group (warfarin dose reduction) with those in the control group (no intervention). Secondary outcomes assessed incidence of thromboembolic and major bleeding events within 30 days of antibiotic completion. Fifty patients were assessed. Forty-nine patients had at least one follow-up appointment; 126 follow-up visits were evaluated. There was a statistically significant difference for the change in therapeutic INR at the first follow-up appointment (p = 0.029) for those patients in the control group. On average, the patients in the intervention group required fewer follow-up visits (p = 0.019). There were no statistically significant differences for the overall rate of therapeutic INR values between groups, as well as no instances of a thromboembolic or major bleeding events during the follow-up period. Clinically significant differences were observed for patients who received a preemptive warfarin dose reduction upon initiation of sulfamethoxazole-trimethoprim or metronidazole. Patients in the intervention group required fewer follow-up appointments and were more likely maintain a therapeutic INR within the 30 days following the antibiotic course. Results of this study will be presented the at Pharmacy and Therapeutics committee in an effort to seek approval for policy development to initiate a local preemptive warfarin dose adjustment as a standard

75 FR 33502 - Special Local Regulation for Marine Events; Temporary Change of Dates for Recurring Marine Events...

Science.gov (United States)

2010-06-14

... activities that typically comprise marine events include sailing regattas, power boat races, swim races and... distribution of power and responsibilities between the Federal Government and Indian tribes. Energy Effects We... Affect Energy Supply, Distribution, or Use. We have determined that it is not a ``significant energy...

Long-term trends in mortality and AIDS-defining events after combination ART initiation among children and adolescents with perinatal HIV infection in 17 middle- and high-income countries in Europe and Thailand: A cohort study.

Directory of Open Access Journals (Sweden)

Ali Judd

2018-01-01

Full Text Available Published estimates of mortality and progression to AIDS as children with HIV approach adulthood are limited. We describe rates and risk factors for death and AIDS-defining events in children and adolescents after initiation of combination antiretroviral therapy (cART in 17 middle- and high-income countries, including some in Western and Central Europe (W&CE, Eastern Europe (Russia and Ukraine, and Thailand.Children with perinatal HIV aged 6 months of cART death and progression to AIDS were assessed. Of 3,526 children included, 32% were from the United Kingdom or Ireland, 30% from elsewhere in W&CE, 18% from Russia or Ukraine, and 20% from Thailand. At cART initiation, median age was 5.2 (IQR 1.4-9.3 years; 35% of children aged 400 c/mL predicted late death. Predictors of early and late progression to AIDS were similar. Study limitations include incomplete recording of US Centers for Disease Control (CDC disease stage B events and serious adverse events in some countries; events that were distributed over a long time period, and that we lacked power to analyse trends in patterns and causes of death over time.In our study, 3,526 children and adolescents with perinatal HIV infection initiated antiretroviral therapy (ART in countries in Europe and Thailand. We observed that over 40% of deaths occurred ≤6 months after cART initiation. Greater early mortality risk in infants, as compared to older children, and in Russia, Ukraine, or Thailand as compared to W&CE, raises concern. Current severe immune suppression, being underweight, and unsuppressed viral load were associated with a higher risk of death at >6 months after initiation of cART.

Estimation of core-damage frequency to evolutionary ALWR [advanced light water reactor] due to seismic initiating events: Task 4.3.3

International Nuclear Information System (INIS)

Brooks, R.D.; Harrison, D.G.; Summitt, R.L.

1990-04-01

The Electric Power Research Institute (EPRI) is presently developing a requirements document for the design of advanced light water reactors (ALWRs). One of the basic goals of the EPRI ALWR Requirements Document is that the core-damage frequency for an ALWR shall be less than 1.0E-5. To aid in this effort, the Department of Energy's Advanced Reactor Severe Accident Program (ARSAP) initiated a functional probabilistic risk assessment (PRA) to determine how effectively the evolutionary plant requirements contained in the existing EPRI Requirements Document assure that this safety goal will be met. This report develops an approximation of the core-damage frequency due to seismic events for both evolutionary plant designs (pressurized-water reactor (PWR) and boiling-water reactor(BWR)) as modeled in the corresponding functional PRAs. Component fragility values were taken directly form information which has been submitted for inclusion in Appendix A to Volume 1 of the EPRI Requirements Document. The results show a seismic core-damage frequency of 5.2E-6 for PWRS and 5.0E-6 for BWRs. Combined with the internal initiators from the functional PRAs, the overall core-damage frequencies are 6.0E-6 for the pwr and BWR, both of which satisfy the 1.0E-5 EPRI goal. In addition, site-specific considerations, such as more rigid components and less conservative fragility data and seismic hazard curves, may further reduce these frequencies. The effect of seismic events on structures are not addressed in this generic evaluation and should be addressed separately on a design-specific basis. 7 refs., 6 figs., 3 tabs

Salinity anomaly as a trigger for ENSO events.

Science.gov (United States)

Zhu, Jieshun; Huang, Bohua; Zhang, Rong-Hua; Hu, Zeng-Zhen; Kumar, Arun; Balmaseda, Magdalena A; Marx, Lawrence; Kinter, James L

2014-10-29

According to the classical theories of ENSO, subsurface anomalies in ocean thermal structure are precursors for ENSO events and their initial specification is essential for skillful ENSO forecast. Although ocean salinity in the tropical Pacific (particularly in the western Pacific warm pool) can vary in response to El Niño events, its effect on ENSO evolution and forecasts of ENSO has been less explored. Here we present evidence that, in addition to the passive response, salinity variability may also play an active role in ENSO evolution, and thus important in forecasting El Niño events. By comparing two forecast experiments in which the interannually variability of salinity in the ocean initial states is either included or excluded, the salinity variability is shown to be essential to correctly forecast the 2007/08 La Niña starting from April 2007. With realistic salinity initial states, the tendency to decay of the subsurface cold condition during the spring and early summer 2007 was interrupted by positive salinity anomalies in the upper central Pacific, which working together with the Bjerknes positive feedback, contributed to the development of the La Niña event. Our study suggests that ENSO forecasts will benefit from more accurate salinity observations with large-scale spatial coverage.

77 FR 25070 - Special Local Regulation for Marine Events; Temporary Change of Dates for Recurring Marine Events...

Science.gov (United States)

2012-04-27

... comprise marine events include sailing regattas, power boat races, swim races and holiday parades. For a.... Energy Effects This rule is not a ``significant energy action'' under Executive Order 12866 and is not likely to have a significant adverse effect on the supply, distribution, or use of energy. Technical...

Scenario evolution: Interaction between event tree construction and numerical analyses

International Nuclear Information System (INIS)

Barr, G.E.; Barnard, R.W.; Dockery, H.A.; Dunn, E.; MacIntyre, A.T.

1991-01-01

Construction of well-posed scenarios for the range of conditions possible at any proposed repository site is a critical first step to assessing total system performance. Even tree construction is the method that is being used to develop potential failure scenarios for the proposed nuclear waste repository at Yucca Mountain. An event tree begins with an initial event or condition. Subsequent events are listed in a sequence, leading eventually to release of radionuclides to the accessible environment. Ensuring the validity of the scenarios requires iteration between problems constructed using scenarios contained in the event tree sequence, experimental results, and numerical analyses. Details not adequately captured within the tree initially may become more apparent as a result of analyses. To illustrate this process, we discuss the iterations used to develop numerical analyses for PACE-90 using basaltic igneous activity and human-intrusion event trees

Event Classification using Concepts

NARCIS (Netherlands)

Boer, M.H.T. de; Schutte, K.; Kraaij, W.

2013-01-01

The semantic gap is one of the challenges in the GOOSE project. In this paper a Semantic Event Classification (SEC) system is proposed as an initial step in tackling the semantic gap challenge in the GOOSE project. This system uses semantic text analysis, multiple feature detectors using the BoW

Emerging Pathogens Initiative (EPI)

Data.gov (United States)

Department of Veterans Affairs — The Emerging Pathogens Initiative (EPI) database contains emerging pathogens information from the local Veterans Affairs Medical Centers (VAMCs). The EPI software...

Development of Quantitative Framework for Event Significance Evaluation

International Nuclear Information System (INIS)

Lee, Durk Hun; Kim, Min Chull; Kim, Inn Seock

2010-01-01

There is an increasing trend in quantitative evaluation of the safety significance of operational events using Probabilistic Safety Assessment (PSA) technique. An integrated framework for evaluation of event significance has been developed by Korea Institute of Nuclear Safety (KINS), which consists of an assessment hierarchy and a number of matrices. The safety significance of various events, e.g., internal or external initiating events that occurred during at-power or shutdown conditions, can be quantitatively analyzed using this framework, and then, the events rated according to their significance. This paper briefly describes the basic concept of the integrated quantitative framework for evaluation of event significance, focusing on the assessment hierarchy

Some algorithms of the events recognition in the Tagged Neutrino Facility

International Nuclear Information System (INIS)

Mukhin, S.A.

1993-01-01

Some algorithms of the events recognition in Tagged Neutrino Facility are described: the event localization in Bars neutrino detector, the off-line trigger, the reconstruction of events vertex, events reconstruction in Tagging Station. The programming package for realization of clusterization methods that have been used for mentioned algorithms realization is presented. 6 refs., 2 tabs

Analysis of unprotected overcooling events in the Integral Fast Reactor

International Nuclear Information System (INIS)

Vilim, R.B.

1989-01-01

Simple analytic models are developed for predicting the response of a metal fueled, liquid-metal cooled reactor to unprotected overcooling events in the balance of plant. All overcooling initiators are shown to fall into two categories. The first category contains these events for which there is no final equilibrium state of constant overcooling, as in the case for a large steam leak. These events are analyzed using a non-flow control mass approach. The second category contains those events which will eventually equilibrate, such as a loss of feedwater heaters. A steady flow control volume analysis shows that these latter events ultimately affect the plant through the feedwater inlet to the steam generator. The models developed for analyzing these two categories provide upper bounds for the reactor's passive response to overcooling accident initiators. Calculation of these bounds for a prototypic plant indicate that failure limits -- eutectic melting, sodium boiling, fuel pin failure -- are not exceeded in any overcooling event. 2 refs

INES: The International Nuclear and Radiological Event Scale User's Manual. 2008 Edition

International Nuclear Information System (INIS)

2009-05-01

The International Nuclear and Radiological Event Scale is used for promptly and consistently communicating to the public the safety significance of events associated with sources of radiation. It covers a wide spectrum of practices, including industrial use such as radiography, use of radiation sources in hospitals, activities at nuclear facilities, and the transport of radioactive material. By putting events from all these practices into a proper perspective, use of INES can facilitate a common understanding between the technical community, the media and the public. The scale was developed in 1990 by international experts convened by the IAEA and the OECD Nuclear Energy Agency (OECD/NEA). It originally reflected the experience gained from the use of similar scales in France and Japan as well as consideration of possible scales in several countries. Since then, the IAEA has managed its development in cooperation with the OECD/NEA and with the support of more than 60 designated National Officers who officially represent the INES member States in the biennial technical meeting of INES. Initially the scale was applied to classify events at nuclear power plants, and then was extended and adapted to enable it to be applied to all installations associated with the civil nuclear industry. More recently, it has been extended and adapted further to meet the growing need for communication of the significance of all events associated with the transport, storage and use of radioactive material and radiation sources. This revised manual brings together the guidance for all uses into a single document. Events are classified on the scale at seven levels: Levels 4-7 are termed 'accidents' and Levels 1-3 'incidents'. Events without safety significance are classified as 'Below Scale/Level 0'. Events that have no safety relevance with respect to radiation or nuclear safety are not classified on the scale. For communication of events to the public, a distinct phrase has been

Elliptic Flow, Initial Eccentricity and Elliptic Flow Fluctuations in Heavy Ion Collisions at RHIC

Science.gov (United States)

Nouicer, Rachid; Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Holzman, B.; Iordanova, A.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wysłouch, B.

2008-12-01

We present measurements of elliptic flow and event-by-event fluctuations established by the PHOBOS experiment. Elliptic flow scaled by participant eccentricity is found to be similar for both systems when collisions with the same number of participants or the same particle area density are compared. The agreement of elliptic flow between Au+Au and Cu+Cu collisions provides evidence that the matter is created in the initial stage of relativistic heavy ion collisions with transverse granularity similar to that of the participant nucleons. The event-by-event fluctuation results reveal that the initial collision geometry is translated into the final state azimuthal particle distribution, leading to an event-by-event proportionality between the observed elliptic flow and initial eccentricity.

American West Tephras – Geomagnetic polarity events redefined through calibration of radio-isotopic and astronomical time

DEFF Research Database (Denmark)

Rivera, Tiffany; Storey, Michael

calibration. Although this geomagnetic event is not part of the most recent geologic timescale, refined ages on short-lived excursions could hold importance to understanding time scales for the wavering nature of Earth’s magnetic field. We propose a new 40Ar/39Ar age for the Quaternary mineral dating standard......The foundation of the EARTHTIME/GTSnext initiative seeks to construct an internally consistent geologic timescale based on astronomical and radio-isotopic geochronology. American west tephras offer a prime opportunity to integrate these two independent timescales with the geomagnetic timescale....... Using an astronomically calibrated age for the monitor mineral Fish Canyon sanidine (FCs;28.201 ± 0.046 Ma, Kuiper, et al., 2008), ages of Pleistocene geomagnetic polarity events are reexamined. Of particular interest, the Quaternary mineral dating standard Alder Creek sandine (ACs) is the type locality...

DESIGNING AN EVENT EXTRACTION SYSTEM

Directory of Open Access Journals (Sweden)

Botond BENEDEK

2017-06-01

Full Text Available In the Internet world, the amount of information available reaches very high quotas. In order to find specific information, some tools were created that automatically scroll through the existing web pages and update their databases with the latest information on the Internet. In order to systematize the search and achieve a result in a concrete form, another step is needed for processing the information returned by the search engine and generating the response in a more organized form. Centralizing events of a certain type is useful first of all for creating a news service. Through this system we are pursuing a knowledge - events from the Internet documents - extraction system. The system will recognize events of a certain type (weather, sports, politics, text data mining, etc. depending on how it will be trained (the concept it has in the dictionary. These events can be provided to the user, or it can also extract the context in which the event occurred, to indicate the initial form in which the event was embedded.

Local Control of Perivascular Malignant Liver Lesions Using Percutaneous Irreversible Electroporation: Initial Experiences

Energy Technology Data Exchange (ETDEWEB)

Eller, Achim, E-mail: Achim.Eller@uk-erlangen.de; Schmid, Axel, E-mail: axel.schmid@uk-erlangen.de [University Hospital Erlangen, University of Erlangen-Nuremberg, Department of Radiology (Germany); Schmidt, Joachim, E-mail: joachim.schmidt@kfa.imed.uni-erlangen.de [University Hospital Erlangen, University of Erlangen-Nuremberg, Department of Anesthesiology (Germany); May, Matthias, E-mail: matthias.may@uk-erlangen.de; Brand, Michael, E-mail: michael.brand@uk-erlangen.de; Saake, Marc, E-mail: marc.saake@uk-erlangen.de; Uder, Michael, E-mail: michael.uder@uk-erlangen.de; Lell, Michael, E-mail: michael.lell@uk-erlangen.de [University Hospital Erlangen, University of Erlangen-Nuremberg, Department of Radiology (Germany)

2015-02-15

PurposeThis study was designed to assess efficacy and safety in the treatment of perivascular malignant liver lesions using percutaneous, computed tomography (CT)-guided irreversible electroporation (IRE).MethodsFourteen patients (mean age 58 ± 11 years) with 18 malignant liver lesions were consecutively enrolled in this study. IRE was performed in patients not eligible for surgery and lesions abutting large vessels or bile ducts. Follow-up exams were performed using multislice-CT (MS-CT) or MRI.ResultsMedium lesion diameter was 20 ± 5 mm. Ten of 14 (71 %) were successfully treated with no local recurrence to date (mean follow-up 388 ± 160 days). One case left initial tumor control unclear and additional RFA was performed 4 weeks after IRE. Complications occurred in 4 of 14 (29 %) cases. In one case, intervention was terminated and abdominal bleeding required laparotomy. In two cases, a postinterventional hematothorax required intervention. In another case, abdominal bleeding could be managed conservatively. No complications related to the bile ducts occurred.ConclusionsPercutaneous IRE seems to be effective in perivascular lesions but is associated with a higher complication rate compared with thermoablative techniques.

Measurement-induced localization of relative degrees of freedom

International Nuclear Information System (INIS)

Cable, Hugo; Knight, Peter L.; Rudolph, Terry

2005-01-01

We present a comprehensive study, using both analytical and numerical methods, of measurement-induced localization of relational degrees of freedom. Looking first at the interference of two optical modes, we find that the localization of the relative phase can be as good for mixed states--in particular, for two initially Poissonian or thermal states--as for the well-known case of two Fock states. In a realistic setup the localization for mixed states is robust and experimentally accessible, and we discuss applications to superselection rules. For an ideal setup we show how a relational Schroedinger cat state emerges and investigate circumstances under which such a state is destroyed. In our second example we consider the localization of relative atomic phase between two Bose Einstein condensates, looking particularly at the build up of spatial interference patterns, an area which has attracted much attention since the work of Javanainen and Yoo. We show that the relative phase localizes much faster than was intimated in previous studies focusing on the emerging interference pattern itself. Finally, we explore the localization of relative spatial parameters discussed in recent work by Rau, Dunningham, and Burnett. We retain their models of indistinguishable scattering but make different assumptions. In particular we consider the case of a real distant observer monitoring light scattering off two particles, who records events only from a narrow field of view. The localization is only partial regardless of the number of observations. This paper contributes to the wider debate on relationism in quantum mechanics, which treats fundamental concepts - reference frames and conservation laws - from a fully quantum and operational perspective

Application of declarative modeling approaches for external events

International Nuclear Information System (INIS)

Anoba, R.C.

2005-01-01

Probabilistic Safety Assessments (PSAs) are increasingly being used as a tool for supporting the acceptability of design, procurement, construction, operation, and maintenance activities at Nuclear Power Plants. Since the issuance of Generic Letter 88-20 and subsequent IPE/IPEEE assessments, the NRC has issued several Regulatory Guides such as RG 1.174 to describe the use of PSA in risk-informed regulation activities. Most PSA have the capability to address internal events including internal floods. As the more demands are being placed for using the PSA to support risk-informed applications, there has been a growing need to integrate other eternal events (Seismic, Fire, etc.) into the logic models. Most external events involve spatial dependencies and usually impact the logic models at the component level. Therefore, manual insertion of external events impacts into a complex integrated fault tree model may be too cumbersome for routine uses of the PSA. Within the past year, a declarative modeling approach has been developed to automate the injection of external events into the PSA. The intent of this paper is to introduce the concept of declarative modeling in the context of external event applications. A declarative modeling approach involves the definition of rules for injection of external event impacts into the fault tree logic. A software tool such as the EPRI's XInit program can be used to interpret the pre-defined rules and automatically inject external event elements into the PSA. The injection process can easily be repeated, as required, to address plant changes, sensitivity issues, changes in boundary conditions, etc. External event elements may include fire initiating events, seismic initiating events, seismic fragilities, fire-induced hot short events, special human failure events, etc. This approach has been applied at a number of US nuclear power plants including a nuclear power plant in Romania. (authors)

User-Generated Social Media Events in Tourism

Directory of Open Access Journals (Sweden)

Estela Marine-Roig

2017-12-01

Full Text Available Social media and mobile technologies have revolutionised communication and particular attention has been given to user-generated content (UGC and the formation of online communities; however, little attention has been given to tourist events entirely generated by users through social media. This paper aims to define and characterise the phenomenon of tourism user-generated events (UGEs through social media around the user’s new empowered role and to assess user-generated social media events’ online socialness. It is also our aim to provide a useful mixed-methodology analysis framework for UGEs in relation to social media and to highlight their interest for organisations. The methodological approach includes a quantitative model to store, analyse and compare events’ online socialness, which is combined with qualitative, participant observation at the events. This approach is applied to the analysis of three Instagram meetups organised by a specific online community at Catalan ski resorts. The paper’s results show the differential characteristic of tourism UGEs: user initiative and empowerment, full organisation and structure, great social media use and UGC production, brand dissemination, attraction capacity, strong online community bond and faithfulness. With UGEs, an event management paradigm shift occurs as organisations are no longer the main initiators and controllers of the event.

The Lusi seismic experiment: An initial study to understand the effect of seismic activity to Lusi

Energy Technology Data Exchange (ETDEWEB)

Karyono, E-mail: karyonosu@gmail.com [Agency for Meteorology, Climatology and Geophysics (BMKG), Jakarta (Indonesia); OSLO University (Norway); Padjadjaran University (UNPAD), Bandung (Indonesia); Mazzini, Adriano; Sugiharto, Anton [OSLO University (Norway); Lupi, Matteo [ETH Zurich (Switzerland); Syafri, Ildrem [Padjadjaran University (UNPAD), Bandung (Indonesia); Masturyono,; Rudiyanto, Ariska; Pranata, Bayu; Muzli,; Widodo, Handi Sulistyo; Sudrajat, Ajat [Agency for Meteorology, Climatology and Geophysics (BMKG), Jakarta (Indonesia)

2015-04-24

The spectacular Lumpur Sidoarjo (Lusi) eruption started in northeast Java on the 29 of May 2006 following a M6.3 earthquake striking the island [1,2]. Initially, several gas and mud eruption sites appeared along the reactivated strike-slip Watukosek fault system [3] and within weeks several villages were submerged by boiling mud. The most prominent eruption site was named Lusi. The Lusi seismic experiment is a project aims to begin a detailed study of seismicity around the Lusi area. In this initial phase we deploy 30 seismometers strategically distributed in the area around Lusi and along the Watukosek fault zone that stretches between Lusi and the Arjuno Welirang (AW) complex. The purpose of the initial monitoring is to conduct a preliminary seismic campaign aiming to identify the occurrence and the location of local seismic events in east Java particularly beneath Lusi.This network will locate small event that may not be captured by the existing BMKG network. It will be crucial to design the second phase of the seismic experiment that will consist of a local earthquake tomography of the Lusi-AW region and spatial and temporal variations of vp/vs ratios. The goal of this study is to understand how the seismicity occurring along the Sunda subduction zone affects to the behavior of the Lusi eruption. Our study will also provide a large dataset for a qualitative analysis of earthquake triggering studies, earthquake-volcano and earthquake-earthquake interactions. In this study, we will extract Green’s functions from ambient seismic noise data in order to image the shallow subsurface structure beneath LUSI area. The waveform cross-correlation technique will be apply to all of recordings of ambient seismic noise at 30 seismographic stations around the LUSI area. We use the dispersive behaviour of the retrieved Rayleigh waves to infer velocity structures in the shallow subsurface.

Initiation of DNA replication: functional and evolutionary aspects

Science.gov (United States)

Bryant, John A.; Aves, Stephen J.

2011-01-01

Background The initiation of DNA replication is a very important and highly regulated step in the cell division cycle. It is of interest to compare different groups of eukaryotic organisms (a) to identify the essential molecular events that occur in all eukaryotes, (b) to start to identify higher-level regulatory mechanisms that are specific to particular groups and (c) to gain insights into the evolution of initiation mechanisms. Scope This review features a wide-ranging literature survey covering replication origins, origin recognition and usage, modification of origin usage (especially in response to plant hormones), assembly of the pre-replication complex, loading of the replisome, genomics, and the likely origin of these mechanisms and proteins in Archaea. Conclusions In all eukaryotes, chromatin is organized for DNA replication as multiple replicons. In each replicon, replication is initiated at an origin. With the exception of those in budding yeast, replication origins, including the only one to be isolated so far from a plant, do not appear to embody a specific sequence; rather, they are AT-rich, with short tracts of locally bent DNA. The proteins involved in initiation are remarkably similar across the range of eukaryotes. Nevertheless, their activity may be modified by plant-specific mechanisms, including regulation by plant hormones. The molecular features of initiation are seen in a much simpler form in the Archaea. In particular, where eukaryotes possess a number of closely related proteins that form ‘hetero-complexes’ (such as the origin recognition complex and the MCM complex), archaeans typically possess one type of protein (e.g. one MCM) that forms a homo-complex. This suggests that several eukaryotic initiation proteins have evolved from archaeal ancestors by gene duplication and divergence. PMID:21508040

The influence of the immediate visual context on incremental thematic role-assignment: evidence from eye-movements in depicted events.

Science.gov (United States)

Knoeferle, Pia; Crocker, Matthew W; Scheepers, Christoph; Pickering, Martin J

2005-02-01

Studies monitoring eye-movements in scenes containing entities have provided robust evidence for incremental reference resolution processes. This paper addresses the less studied question of whether depicted event scenes can affect processes of incremental thematic role-assignment. In Experiments 1 and 2, participants inspected agent-action-patient events while listening to German verb-second sentences with initial structural and role ambiguity. The experiments investigated the time course with which listeners could resolve this ambiguity by relating the verb to the depicted events. Such verb-mediated visual event information allowed early disambiguation on-line, as evidenced by anticipatory eye-movements to the appropriate agent/patient role filler. We replicated this finding while investigating the effects of intonation. Experiment 3 demonstrated that when the verb was sentence-final and thus did not establish early reference to the depicted events, linguistic cues alone enabled disambiguation before people encountered the verb. Our results reveal the on-line influence of depicted events on incremental thematic role-assignment and disambiguation of local structural and role ambiguity. In consequence, our findings require a notion of reference that includes actions and events in addition to entities (e.g. Semantics and Cognition, 1983), and argue for a theory of on-line sentence comprehension that exploits a rich inventory of semantic categories.

78 FR 35135 - Special Local Regulations and Safety Zones; Recurring Events in Northern New England

Science.gov (United States)

2013-06-12

........... Event Type: Tall Ship Parade. Sponsor: Boothbay Region Chamber of Commerce. Date: June 26, 2013. Time: 1... Races....... Event Type: Power Boat Race. Sponsor: Winter Harbor Chamber of Commerce. Date: August 10...). Windjammer Days Fireworks Event Type: Fireworks Display. Sponsor: Boothbay Harbor Region Chamber of Commerce...

Play Initiating Behaviors and Responses in Red Colobus Monkeys

Science.gov (United States)

Worch, Eric A.

2012-01-01

Red colobus monkeys are playful primates, making them an important species in which to study animal play. The author examines play behaviors and responses in the species for its play initiation events, age differences in initiating frequency and initiating behavior, and the types of social play that result from specific initiating behaviors. Out…

Sensitivity of the Reaction Mechanism of the Ozone Depletion Events during the Arctic Spring on the Initial Atmospheric Composition of the Troposphere

Directory of Open Access Journals (Sweden)

Le Cao

2016-09-01

Full Text Available Ozone depletion events (ODEs during the Arctic spring have been investigated since the 1980s. It was found that the depletion of ozone is highly associated with the release of halogens, especially bromine containing compounds. These compounds originate from various substrates such as the ice/snow-covered surfaces in Arctic. In the present study, the dependence of the mixing ratios of ozone and principal bromine species during ODEs on the initial composition of the Arctic atmospheric boundary layer was investigated by using a concentration sensitivity analysis. This analysis was performed by implementing a reaction mechanism representing the ozone depletion and halogen release in the box model KINAL (KInetic aNALysis of reaction mechanics. The ratios between the relative change of the mixing ratios of particular species such as ozone and the variation in the initial concentration of each atmospheric component were calculated, which indicate the relative importance of each initial species in the chemical kinetic system. The results of the computations show that the impact of various chemical species is different for ozone and bromine containing compounds during the depletion of ozone. It was found that CH3CHO critically controls the time scale of the complete removal of ozone. However, the rate of the ozone loss and the maximum values of bromine species are only slightly influenced by the initial value of CH3CHO. In addition, according to the concentration sensitivity analysis, the reduction of initial Br2 was found to cause a significant retardant of the ODE while the initial mixing ratio of HBr exerts minor influence on both ozone and bromine species. In addition, it is also interesting to note that the increase of C2H2 would significantly raise the amount of HOBr and Br in the atmosphere while the ozone depletion is hardly changed.

Highlight report local initiatives. Experiences with electric transport; Highlight report lokale initiatieven. Ervaringen met elektrisch vervoer

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-06-15

In March 2013 Linkingreen and XTNT started a survey on local electric transportation initiatives. The aim is to learn from the experiences, problems and obstacles of business users of electric vehicles: cars, vans or trucks, scooters, boats and special vehicles (e.g. garbage trucks) that are all-electric or plug-in (with plug). In this brief report, the main results are presented [Dutch] In maart 2013 is door Linkingreen en XTNT in opdracht van Agentschap NL een enquete uitgezet naar lokale initiatieven elektrisch vervoer. Doel is te leren wat de ervaringen, knelpunten en belemmeringen zijn van zakelijke gebruikers van elektrisch vervoer: personenauto's, bestel- of vrachtauto's, scooters, vaartuigen en bijzondere voertuigen (vuilniswagens etc.) die volledig elektrische of plug in (met stekker) zijn. In dit korte verslag zijn de belangrijkste resultaten opgenomen.

TEMAC, Top Event Sensitivity Analysis

International Nuclear Information System (INIS)

Iman, R.L.; Shortencarier, M.J.

1988-01-01

1 - Description of program or function: TEMAC is designed to permit the user to easily estimate risk and to perform sensitivity and uncertainty analyses with a Boolean expression such as produced by the SETS computer program. SETS produces a mathematical representation of a fault tree used to model system unavailability. In the terminology of the TEMAC program, such a mathematical representation is referred to as a top event. The analysis of risk involves the estimation of the magnitude of risk, the sensitivity of risk estimates to base event probabilities and initiating event frequencies, and the quantification of the uncertainty in the risk estimates. 2 - Method of solution: Sensitivity and uncertainty analyses associated with top events involve mathematical operations on the corresponding Boolean expression for the top event, as well as repeated evaluations of the top event in a Monte Carlo fashion. TEMAC employs a general matrix approach which provides a convenient general form for Boolean expressions, is computationally efficient, and allows large problems to be analyzed. 3 - Restrictions on the complexity of the problem - Maxima of: 4000 cut sets, 500 events, 500 values in a Monte Carlo sample, 16 characters in an event name. These restrictions are implemented through the FORTRAN 77 PARAMATER statement

Estimative of core damage frequency in IPEN'S IEA-R1 research reactor due to the initiating event of loss of coolant caused by large rupture in the pipe of the primary circuit

International Nuclear Information System (INIS)

Hirata, Daniel Massami; Sabundjian, Gaiane; Cabral, Eduardo Lobo Lustosa

2009-01-01

The National Commission of Nuclear Energy (CNEN), which is the Brazilian nuclear regulatory commission, imposes safety and licensing standards in order to ensure that the nuclear power plants operate in a safe way. For licensing a nuclear reactor one of the demands of CNEN is the simulation of some accidents and thermalhydraulic transients considered as design base to verify the integrity of the plant when submitted to adverse conditions. The accidents that must be simulated are those that present large probability to occur or those that can cause more serious consequences. According to the FSAR (Final Safety Analysis Report) the initiating event that can cause the largest damage in the core, of the IEA-R1 research reactor at IPEN-CNEN/SP, is the LOCA (Loss of Coolant Accident). The objective of this paper is estimate the frequency of the IEA-R1 core damage, caused by this initiating event. In this paper we analyze the accident evolution and performance of the systems which should mitigate this event: the Emergency Coolant Core System (ECCS) and the isolated pool system. They will be analyzed by means of the event tree. In this work the reliability of these systems are also quantified using the fault tree. (author)

Intensified Local Resource Mobilization for the Polio Eradication Initiative: The Experience of World Health Organization in Nigeria During 2008-2015.

Science.gov (United States)

Yehualashet, Yared G; Horton, Janet; Mkanda, Pascal; Vaz, Rui G; Afolabi, Oluwole; Gashu, Sisay G; Banda, Richard; O'Malley, Helena; Nsubuga, Peter

2016-05-01

Since the World Health Assembly (WHA) resolved in 1988 to eradicate poliovirus, several rounds of immunization campaigns have been conducted by member states. By 2000, with the support of the Global Polio Eradication Initiative (GPEI) partners, the number of polio cases decreased by 99%. Eradicating the remaining 1% proved to be more challenging. Although the GPEI, being the largest public health project, required >$9 billion between 1988 and 2012, economic analysis showed the estimated incremental net benefits of $40 billion-$50 billion between 1988 and 2035. In 2012, the WHA declared that the completion of poliovirus eradication is a programmatic emergency for global public health. Nigeria, as one of 3 remaining polio-endemic countries, developed an emergency plan to interrupt the transmission of poliovirus. The plan included the introduction or scale-up of various new innovations and strategies, which had substantial financial implication. This is a retrospective study to document the intensified resource mobilization efforts made by the World Health Organization (WHO) in Nigeria to meet the increased financial requirements and bridge the remaining gap in funding. In addition to the established coordination platforms, the WHO Nigeria Country Office team directly engaged with national authorities, donors, and partners throughout the process of resource requirement analysis, project appraisals, proposal development, and implementation of activities, joint monitoring, and evaluation exercises. The office strengthened its capacity for direct funds disbursement and systematic implementation of a rigorous accountability framework. Between 2008 and May 2015, $538 million was mobilized locally, of which 82% was mobilized since 2012. The percentage of the total funding requirements that were locally mobilized averaged 31% between 2008 and 2011 and increased to 70% between 2012 and May 2015. During the same period, the WHO Nigeria Country Office team produced and

Initial conditions and entanglement sudden death

International Nuclear Information System (INIS)

Qian, Xiao-Feng; Eberly, J.H.

2012-01-01

We report results bearing on the behavior of non-local decoherence and its potential for being managed or even controlled. The decoherence process known as entanglement sudden death (ESD) can drive prepared entanglement to zero at the same time that local coherences and fidelity remain non-zero. For a generic ESD-susceptible Bell superposition state, we provide rules restricting the occurrence and timing of ESD, amounting to management tools over a continuous variation of initial conditions. These depend on only three parameters: initial purity, entanglement and excitation. Knowledge or control of initial phases is not needed. -- Highlights: ► We study the possibility of managing disentanglement through initial conditions. ► The initial parameters are the amount of entanglement, excitation, and purity. ► Entanglement sudden death (ESD) free and ESD susceptible phases are identified. ► ESD onset time is also presented in the ESD susceptible phase. ► Our results may guide experiments to prepare ESD free or delayed ESD states.

On crack initiation in notched, cross-plied polymer matrix composites

Science.gov (United States)

Yang, Q. D.; Schesser, D.; Niess, M.; Wright, P.; Mavrogordato, M. N.; Sinclair, I.; Spearing, S. M.; Cox, B. N.

2015-05-01

The physics of crack initiation in a polymer matrix composite are investigated by varying the modeling choices made in simulations and comparing the resulting predictions with high-resolution in situ images of cracks. Experimental data were acquired using synchrotron-radiation computed tomography (SRCT) at a resolution on the order of 1 μm, which provides detailed measurement of the location, shape, and size of small cracks, as well as the crack opening and shear displacements. These data prove sufficient to discriminate among competing physical descriptions of crack initiation. Simulations are executed with a high-fidelity formulation, the augmented finite element method (A-FEM), which permits consideration of coupled damage mechanisms, including both discrete cracks and fine-scale continuum damage. The discrete cracks are assumed to be nonlinear fracture events, governed by reasonably general mixed-mode cohesive laws. Crack initiation is described in terms of strength parameters within the cohesive laws, so that the cohesive law provides a unified model for crack initiation and growth. Whereas the cracks investigated are typically 1 mm or less in length, the fine-scale continuum damage refers to irreversible matrix deformation occurring over gauge lengths extending down to the fiber diameter (0.007 mm). We find that the location and far-field stress for crack initiation are predicted accurately only if the variations of local stress within plies and in the presence of stress concentrators (notches, etc.) are explicitly computed and used in initiation criteria; stress redistribution due to matrix nonlinearity that occurs prior to crack initiation is accounted for; and a mixed-mode criterion is used for crack initiation. If these factors are not all considered, which is the case for commonly used failure criteria, predictions of the location and far-field stress for initiation are not accurate.

Local ancestry transitions modify snp-trait associations.

Science.gov (United States)

Fish, Alexandra E; Crawford, Dana C; Capra, John A; Bush, William S

2018-01-01

Genomic maps of local ancestry identify ancestry transitions - points on a chromosome where recent recombination events in admixed individuals have joined two different ancestral haplotypes. These events bring together alleles that evolved within separate continential populations, providing a unique opportunity to evaluate the joint effect of these alleles on health outcomes. In this work, we evaluate the impact of genetic variants in the context of nearby local ancestry transitions within a sample of nearly 10,000 adults of African ancestry with traits derived from electronic health records. Genetic data was located using the Metabochip, and used to derive local ancestry. We develop a model that captures the effect of both single variants and local ancestry, and use it to identify examples where local ancestry transitions significantly interact with nearby variants to influence metabolic traits. In our most compelling example, we find that the minor allele of rs16890640 occuring on a European background with a downstream local ancestry transition to African ancestry results in significantly lower mean corpuscular hemoglobin and volume. This finding represents a new way of discovering genetic interactions, and is supported by molecular data that suggest changes to local ancestry may impact local chromatin looping.

Localizing the Global and Globalizing the Local: Opportunities and Challenges in Bali Island Tourism Development

Directory of Open Access Journals (Sweden)

I Nyoman Darma Putra

2013-10-01

Full Text Available Abstract In September and October 2013, only one week apart,Bali hosted two global events in the upper class markettourism resort Nusa Dua. The first event was the MissWorld beauty pageant, and the other one was the APECSummit. Thousands of journalists from all over the worldcovered these events. From a tourism marketing point ofview, these two prestigious events helped Bali boost itspopularity through global mass media. Historically, sincethe early phase of its development, Bali’s tourism industryhas received many benefits from global forces initiallychanneled out through the Dutch colonial power in the firstdecade of the twentieth century and later through nationaland multinational corporations. The recent enlisting byUNESCO of Bali’s cultural landscape as a world heritagesite (2012 provides yet another great example of how Balicontinues to receive global endorsement by world institutions as a unique tourism destination. This paper discusesopportunities and challenges caused by globalizationand localization phenomena in the management of Bali’stourism island destination. Bali’s experiences provide aninteresting example of how global and local stakeholdersdevelop the island tourism in a sustainable manner whileat the same time continuing to preserve its local arts andculture as one of its main attractions. While there aremany examples how both forces contribute to numerousopportunities toward the development of Bali’s tourism,it is also true to state that impacts of globalization causesvarious forms of distraction for the island’s ability to takefull control of its vast move of development.

EVENT AND MUSIC FESTIVAL TOURISM IN FINLAND : Ostrobothnia Music Festivals

OpenAIRE

Maharjan, Suresh

2014-01-01

This thesis will emphasize the importance of events and music event tourism. It illustrates music and event as a tool to attract and promote tourism in a specific destination. However, every place could not be developed as a tourism product, but a well-planned and successful music event plays a vital role in developing those places as a possible tourism product. Successful music events benefit both the organizer and the country’s economy and also the local community. If all the components...

NASA SPoRT Initialization Datasets for Local Model Runs in the Environmental Modeling System

Science.gov (United States)

Case, Jonathan L.; LaFontaine, Frank J.; Molthan, Andrew L.; Carcione, Brian; Wood, Lance; Maloney, Joseph; Estupinan, Jeral; Medlin, Jeffrey M.; Blottman, Peter; Rozumalski, Robert A.

2011-01-01

The NASA Short-term Prediction Research and Transition (SPoRT) Center has developed several products for its National Weather Service (NWS) partners that can be used to initialize local model runs within the Weather Research and Forecasting (WRF) Environmental Modeling System (EMS). These real-time datasets consist of surface-based information updated at least once per day, and produced in a composite or gridded product that is easily incorporated into the WRF EMS. The primary goal for making these NASA datasets available to the WRF EMS community is to provide timely and high-quality information at a spatial resolution comparable to that used in the local model configurations (i.e., convection-allowing scales). The current suite of SPoRT products supported in the WRF EMS include a Sea Surface Temperature (SST) composite, a Great Lakes sea-ice extent, a Greenness Vegetation Fraction (GVF) composite, and Land Information System (LIS) gridded output. The SPoRT SST composite is a blend of primarily the Moderate Resolution Imaging Spectroradiometer (MODIS) infrared and Advanced Microwave Scanning Radiometer for Earth Observing System data for non-precipitation coverage over the oceans at 2-km resolution. The composite includes a special lake surface temperature analysis over the Great Lakes using contributions from the Remote Sensing Systems temperature data. The Great Lakes Environmental Research Laboratory Ice Percentage product is used to create a sea-ice mask in the SPoRT SST composite. The sea-ice mask is produced daily (in-season) at 1.8-km resolution and identifies ice percentage from 0 100% in 10% increments, with values above 90% flagged as ice.

Quantitative proteomic assessment of very early cellular signaling events

DEFF Research Database (Denmark)

Dengjel, Joern; Akimov, Vyacheslav; Olsen, Jesper V

2007-01-01

Technical limitations have prevented proteomic analyses of events occurring less than 30 s after signal initiation. We developed an automated, continuous quench-flow system allowing quantitative proteomic assessment of very early cellular signaling events (qPACE) with a time resolution of 1 s...

Global and local consistencies in distributed fault diagnosis for discrete-event systems

NARCIS (Netherlands)

Su, R.; Wonham, W.M.

2005-01-01

In this paper, we present a unified framework for distributed diagnosis. We first introduce the concepts of global and local consistency in terms of supremal global and local supports, then present two distributed diagnosis problems based on them. After that, we provide algorithms to achieve

Accident sequence precursor events with age-related contributors

Energy Technology Data Exchange (ETDEWEB)

Murphy, G.A.; Kohn, W.E.

1995-12-31

The Accident Sequence Precursor (ASP) Program at ORNL analyzed about 14.000 Licensee Event Reports (LERs) filed by US nuclear power plants 1987--1993. There were 193 events identified as precursors to potential severe core accident sequences. These are reported in G/CR-4674. Volumes 7 through 20. Under the NRC Nuclear Plant Aging Research program, the authors evaluated these events to determine the extent to which component aging played a role. Events were selected that involved age-related equipment degradation that initiated an event or contributed to an event sequence. For the 7-year period, ORNL identified 36 events that involved aging degradation as a contributor to an ASP event. Except for 1992, the percentage of age-related events within the total number of ASP events over the 7-year period ({approximately}19%) appears fairly consistent up to 1991. No correlation between plant ape and number of precursor events was found. A summary list of the age-related events is presented in the report.

Event-Triggered Distributed Control of Nonlinear Interconnected Systems Using Online Reinforcement Learning With Exploration.

Science.gov (United States)

Narayanan, Vignesh; Jagannathan, Sarangapani

2017-09-07

In this paper, a distributed control scheme for an interconnected system composed of uncertain input affine nonlinear subsystems with event triggered state feedback is presented by using a novel hybrid learning scheme-based approximate dynamic programming with online exploration. First, an approximate solution to the Hamilton-Jacobi-Bellman equation is generated with event sampled neural network (NN) approximation and subsequently, a near optimal control policy for each subsystem is derived. Artificial NNs are utilized as function approximators to develop a suite of identifiers and learn the dynamics of each subsystem. The NN weight tuning rules for the identifier and event-triggering condition are derived using Lyapunov stability theory. Taking into account, the effects of NN approximation of system dynamics and boot-strapping, a novel NN weight update is presented to approximate the optimal value function. Finally, a novel strategy to incorporate exploration in online control framework, using identifiers, is introduced to reduce the overall cost at the expense of additional computations during the initial online learning phase. System states and the NN weight estimation errors are regulated and local uniformly ultimately bounded results are achieved. The analytical results are substantiated using simulation studies.

Continental-Scale Estimates of Runoff Using Future Climate Storm Events

Science.gov (United States)

Recent runoff events have had serious repercussions to both natural ecosystems and human infrastructure. Understanding how shifts in storm event intensities are expected to change runoff responses are valuable for local, regional, and landscape planning. To address this challenge...

Local geomagnetic events associated with displacements on the san andreas fault.

Science.gov (United States)

Breiner, S; Kovach, R L

1967-10-06

The piezomagnetic properties of rock suggest that a change in subsurface stress will manifest itself as a change in the magnetic susceptibility and remanent magnetization and hence the local geomagnetic field. A differential array of magnetometers has been operating since late 1965 on the San Andreas fault in the search for piezomagnetic signals under conditions involving active fault stress. Local changes in the geomagnetic field have been observed near Hollister, California, some tens of hours preceding the onset of abrupt creep displacement on the San Andreas fault.

Simulating Flaring Events via an Intelligent Cellular Automata Mechanism

Science.gov (United States)

Dimitropoulou, M.; Vlahos, L.; Isliker, H.; Georgoulis, M.

2010-07-01

We simulate flaring events through a Cellular Automaton (CA) model, in which, for the first time, we use observed vector magnetograms as initial conditions. After non-linear force free extrapolation of the magnetic field from the vector magnetograms, we identify magnetic discontinuities, using two alternative criteria: (1) the average magnetic field gradient, or (2) the normalized magnetic field curl (i.e. the current). Magnetic discontinuities are identified at the grid-sites where the magnetic field gradient or curl exceeds a specified threshold. We then relax the magnetic discontinuities according to the rules of Lu and Hamilton (1991) or Lu et al. (1993), i.e. we redistribute the magnetic field locally so that the discontinuities disappear. In order to simulate the flaring events, we consider several alternative scenarios with regard to: (1) The threshold above which magnetic discontinuities are identified (applying low, high, and height-dependent threshold values); (2) The driving process that occasionally causes new discontinuities (at randomly chosen grid sites, magnetic field increments are added that are perpendicular (or may-be also parallel) to the existing magnetic field). We address the question whether the coronal active region magnetic fields can indeed be considered to be in the state of self-organized criticality (SOC).

High-Resolution, Long-Slit Spectroscopy of VY Canis Majoris: The Evidence for Localized High Mass Loss Events

Science.gov (United States)

Humphreys, Roberta M.; Davidson, Kris; Ruch, Gerald; Wallerstein, George

2005-01-01

High spatial and spectral resolution spectroscopy of the OH/IR supergiant VY CMa and its circumstellar ejecta reveals evidence for high mass loss events from localized regions on the star occurring over the past 1000 yr. The reflected absorption lines and the extremely strong K I emission lines show a complex pattern of velocities in the ejecta. We show that the large, dusty northwest arc, expanding at ~50 km s-1 with respect to the embedded star, is kinematically distinct from the surrounding nebulosity and was ejected about 400 yr ago. Other large, more filamentary loops were probably expelled as much as 800-1000 yr ago, whereas knots and small arcs close to the star resulted from more recent events 100-200 yr ago. The more diffuse, uniformly distributed gas and dust is surprisingly stationary, with little or no velocity relative to the star. This is not what we would expect for the circumstellar material from an evolved red supergiant with a long history of mass loss. We therefore suggest that the high mass loss rate for VY CMa is a measure of the mass carried out by these specific ejections accompanied by streams or flows of gas through low-density regions in the dust envelope. VY CMa may thus be our most extreme example of stellar activity, but our results also bring into question the evolutionary state of this famous star. In a separate appendix, we discuss the origin of the very strong K I and other rare emission lines in its spectrum.

Understanding local water conflict and cooperation: The case of Namwala District, Zambia

Science.gov (United States)

Funder, Mikkel; Mweemba, Carol; Nyambe, Imasiku; van Koppen, Barbara; Ravnborg, Helle Munk

Understanding the nature of water conflict and cooperation is a crucial element in water governance within Integrated Water Resources Management (IWRM). Much of the recent attention to the issue has however focused on transboundary aspects, while we know rather less about the nature and dynamics of local water conflict and cooperation. Drawing on the work of the collaborative Competing for Water Research Programme, this article presents selected findings from a quantitative and qualitative mapping and exploration of water conflict and cooperation events in Namwala District of Zambia. It is found that local water competition situations often involve both conflictive and cooperative events in a dynamic succession of each other, but also that the majority of events are conflictive, and that they primarily take place between different types of water uses, and less frequently among the same types of uses. There is a distinct tendency for both conflictive and cooperative events to originate in the dry season, and many events are associated with water infrastructure development, particularly boreholes. The study found that most conflictive and cooperative events took place within individual communities, and only to a lesser extent between two or more communities or between districts. While third parties are involved in some events, these are primarily local village institutions such as Headmen. The article concludes by discussing the implications of these findings for local water governance, including the need to ensure that the very localized nature of such conflict and cooperation events is taken into consideration in the institutional development of IWRM.

Modeling for operational event risk assessment

International Nuclear Information System (INIS)

Sattison, M.B.

1997-01-01

The U.S. Nuclear Regulatory Commission has been using risk models to evaluate the risk significance of operational events in U.S. commercial nuclear power plants for more seventeen years. During that time, the models have evolved in response to the advances in risk assessment technology and insights gained with experience. Evaluation techniques fall into two categories, initiating event assessments and condition assessments. The models used for these analyses have become uniquely specialized for just this purpose

Development and Initial Validation of a Patient-Reported Adverse Drug Event Questionnaire

NARCIS (Netherlands)

de Vries, Sieta T.; Mol, Peter G. M.; de Zeeuw, Dick; Haaijer-Ruskamp, Flora M.; Denig, Petra

2013-01-01

Background Direct patient reporting of adverse drug events (ADEs) is relevant for the evaluation of drug safety. To collect such data in clinical trials and postmarketing studies, a valid questionnaire is needed that can measure all possible ADEs experienced by patients. Objective Our aim was to

Local/regional policies: Acting globally by thinking locally

International Nuclear Information System (INIS)

Hillsman, E.L.

1991-01-01

Policies to reduce greenhouse gas emissions from present levels will require changes in local and regional decision making as well as decisions made at national and multinational scales. A number of cities and states have taken action to reduce emissions either directly or as a byproduct of solving local problems such as air quality. These initiatives represent a potential resource to be mobilized in national policy. A series of case studies is under way to understand the decision making involved and its implications, and to identify ways that national policy might support and benefit from local efforts. Preliminary results from the first of these case studies indicate that reductions in greenhouse gas emissions may be greater when set as a direct target than when resulting as a byproduct of other local problem solving

Utilization of Local Law Enforcement Aerial Resources in Consequence Management (CM) Response

Energy Technology Data Exchange (ETDEWEB)

Wasiolek, Piotr T.; Malchow, Russell L.

2013-03-12

During the past decade the U.S. Department of Homeland Security (DHS) was instrumental in enhancing the nation’s ability to detect and prevent a radiological or nuclear attack in the highest risk cities. Under the DHS Securing the Cities initiative, nearly 13,000 personnel in the New York City region have been trained in preventive radiological and nuclear detection operations, and nearly 8,500 pieces of radiological detection equipment have been funded. As part of the preventive radiological/nuclear detection (PRND) mission, several cities have received funding to purchase commercial aerial radiation detection systems. In 2008, the U.S. Department of Energy, National Nuclear Security Administration Aerial Measuring System (AMS) program started providing Mobile Aerial Radiological Surveillance (MARS) training to such assets, resulting in over 150 HAZMAT teams’ officers and pilots from 10 law enforcement organizations and fire departments being trained in the aerial radiation detection. From the beginning, the MARS training course covered both the PRND and consequence management (CM) missions. Even if the law enforcement main focus is PRND, their aerial assets can be utilized in the collection of initial radiation data for post-event radiological CM response. Based on over 50 years of AMS operational experience and information collected during MARS training, this presentation will focus on the concepts of CM response using aerial assets as well as utilizing law enforcement/fire department aerial assets in CM. Also discussed will be the need for establishing closer relationships between local jurisdictions’ aerial radiation detection capabilities and state and local radiation control program directors, radiological health department managers, etc. During radiological events these individuals may become primary experts/advisers to Incident Commanders for radiological emergency response, especially in the early stages of a response. The knowledge of the existence

Focus on Local Reaction.

Science.gov (United States)

Howe, Rod

1999-01-01

Discusses how the student newspaper "The Lance" (at Westside High School in Omaha, Nebraska) covered the shootings at Columbine High School. Notes that the staff localized the event and brought the student body into the story. (RS)

Positron Emission Tomography (PET) Evaluation After Initial Chemotherapy and Radiation Therapy Predicts Local Control in Rhabdomyosarcoma

Energy Technology Data Exchange (ETDEWEB)

Dharmarajan, Kavita V., E-mail: dharmark@mskcc.org [Departments of Radiation Oncology, Pediatric Oncology, and Nuclear Medicine, Memorial Sloan-Kettering, New York, New York (United States); Wexler, Leonard H.; Gavane, Somali; Fox, Josef J.; Schoder, Heiko; Tom, Ashlyn K.; Price, Alison N.; Meyers, Paul A.; Wolden, Suzanne L. [Departments of Radiation Oncology, Pediatric Oncology, and Nuclear Medicine, Memorial Sloan-Kettering, New York, New York (United States)

2012-11-15

Purpose: 18-fluorodeoxyglucose positron emission tomography (PET) is already an integral part of staging in rhabdomyosarcoma. We investigated whether primary-site treatment response characterized by serial PET imaging at specific time points can be correlated with local control. Patients and Methods: We retrospectively examined 94 patients with rhabdomyosarcoma who received initial chemotherapy 15 weeks (median) before radiotherapy and underwent baseline, preradiation, and postradiation PET. Baseline PET standardized uptake values (SUVmax) and the presence or absence of abnormal uptake (termed PET-positive or PET-negative) both before and after radiation were examined for the primary site. Local relapse-free survival (LRFS) was calculated according to baseline SUVmax, PET-positive status, and PET-negative status by the Kaplan-Meier method, and comparisons were tested with the log-rank test. Results: The median patient age was 11 years. With 3-year median follow-up, LRFS was improved among postradiation PET-negative vs PET-positive patients: 94% vs 75%, P=.02. By contrast, on baseline PET, LRFS was not significantly different for primary-site SUVmax {<=}7 vs >7 (median), although the findings suggested a trend toward improved LRFS: 96% for SUVmax {<=}7 vs 79% for SUVmax >7, P=.08. Preradiation PET also suggested a statistically insignificant trend toward improved LRFS for PET-negative (97%) vs PET-positive (81%) patients (P=.06). Conclusion: Negative postradiation PET predicted improved LRFS. Notably, 77% of patients with persistent postradiation uptake did not experience local failure, suggesting that these patients could be closely followed up rather than immediately referred for intervention. Negative baseline and preradiation PET findings suggested statistically insignificant trends toward improved LRFS. Additional study may further understanding of relationships between PET findings at these time points and outcome in rhabdomyosarcoma.

Local Development Responses in Zambia:The Case of Kitwe ...

African Journals Online (AJOL)

growth in planning initiatives for Local Economic Development (LED). This article examines LED activities in the city of Kitwe, against the backdrop of regional and local economic decline, two different sets of responses may be recognised: (i) local government led initiatives and (ii) 'bottom up' LED responses arising from the ...

Results of external beam irradiation for rectal carcinomas locally recurrent after local excision or electrocoagulation

International Nuclear Information System (INIS)

Shun Wong, C.; Cummings, B.J.; Keane, T.J.; O'Sullivan, Brian; Catton, C.N.

1991-01-01

The outcome of 42 patients who developed locally recurrent rectal carcinoma after initial local excision or electrocoagulation was presented. Five patients received combined surgery and radiotherapy (XRT). The remaining 37 patients were managed by XRT alone. The overall 5 years actuarial survival and local control rates were 21 and 22 percent, respectively. For patients who received XRT alone, the 5 year actuarial survival and local control rates were 20 and 15 percent, resp. The corresponding figures were 35 and 40 percent for patients who received a total XRT dose of 50 Gy or more. One patient who underwent combined treatment developed rectal and bladder incontinence requiring surgery. For patients with rectal recurrence after initial conservative surgery, XRT is an alternative to abdominoperipheral resection if major resection is contraindicated. (author). 13 refs.; 2 tabs

Preliminary Results of a U.S. Deep South Warm Season Deep Convective Initiation Modeling Experiment using NASA SPoRT Initialization Datasets for Operational National Weather Service Local Model Runs

Science.gov (United States)

Medlin, Jeffrey M.; Wood, Lance; Zavodsky, Brad; Case, Jon; Molthan, Andrew

2012-01-01

The initiation of deep convection during the warm season is a forecast challenge in the relative high instability and low wind shear environment of the U.S. Deep South. Despite improved knowledge of the character of well known mesoscale features such as local sea-, bay- and land-breezes, observations show the evolution of these features fall well short in fully describing the location of first initiates. A joint collaborative modeling effort among the NWS offices in Mobile, AL, and Houston, TX, and NASA s Short-term Prediction Research and Transition (SPoRT) Center was undertaken during the 2012 warm season to examine the impact of certain NASA produced products on the Weather Research and Forecasting Environmental Modeling System. The NASA products were: a 4-km Land Information System data, a 1-km sea surface temperature analysis, and a 4-km greenness vegetation fraction analysis. Similar domains were established over the southeast Texas and Alabama coastlines, each with a 9 km outer grid spacing and a 3 km inner nest spacing. The model was run at each NWS office once per day out to 24 hours from 0600 UTC, using the NCEP Global Forecast System for initial and boundary conditions. Control runs without the NASA products were made at the NASA SPoRT Center. The NCAR Model Evaluation Tools verification package was used to evaluate both the forecast timing and location of the first initiates, with a focus on the impacts of the NASA products on the model forecasts. Select case studies will be presented to highlight the influence of the products.

Models for ductile crack initiation and tearing resistance under mode 1 loading in pressure vessel steels

International Nuclear Information System (INIS)

Jones, M.R.

1988-06-01

Micromechanistic models are presented which aim to predict plane strain ductile initiation toughness, tearing resistance and notched bar fracture strains in pressure vessel steels under monotonically increasing tensile (mode 1) loading. The models for initiation toughness and tearing resistance recognize that ductile fracture proceeds by the growth and linkage of voids with the crack-tip. The models are shown to predict the trend of initiation toughness with inclusion spacing/size ratio and can bound the available experimental data. The model for crack growth can reproduce the tearing resistance of a pressure vessel steel up to and just beyond crack growth initiation. The fracture strains of notched bars pulled in tension are shown to correspond to the achievement of a critical volume fraction of voids. This criterion is combined with the true stress - true strain history of a material point ahead of a blunting crack-tip to predict the initiation toughness. An attempt was made to predict the fracture strains of notched tensile bars by adopting a model which predicts the onset of a shear localization phenomenon. Fracture strains of the correct order are computed only if a ''secondary'' void nucleation event at carbide precipitates is taken into account. (author)

Design approach to local blockages

International Nuclear Information System (INIS)

Roychowdhury, D.G.; Govindarajan, S.; Chetal, S.C.; Bhoje, S.B.

2000-01-01

In LMFBR, whole core meltdown accident falls in residual risk category. Propagation of a local fault to whole core, however, needs attention. Subassembly accidents are divided into two categories, Design Basis and Beyond Design Basis accidents. Design Basis is further classified into four categories. All events affecting fuel pin performance are identified and categorised, Total Instantaneous Blockage has been identified as the envelope of all local faults and categorised as BDB event and the safety objective is to demonstrate that no damage will propagate beyond six neighbouring SA. A core catcher has been provided for retention of core debris and cooling it by natural convection. Local blockages may be active and passive. Active blockages can be detected by DND signal. For passive blockages, detection is difficult. Hence, development of a finite volume computer code based on the porous body formulation has been undertaken to define the maximum allowable defect. Experimental programmes have been undertaken to understand blockage mechanism, define maximum credible defect and the thermalhydraulic behaviour of SA with local blockages. Also an experimental programme with a totally blocked SA with a bundle of heated pins has been undertaken to understand the behaviour of the SA. (author)

Multiple Event Localization in a Sparse Acoustic Sensor Network Using UAVs as Data Mules

Science.gov (United States)

2012-12-01

the events to arrive in different orders at the sensors. Consequently , simple rules to group the ToAs from an event at different sensors, such as...a Microhard radio to forward the ToAs to the mule-UAV. Two Procerus Unicorn UAVs were used with different payloads. The imaging- UAV was equipped

Effects of global and local contexts on chord processing: An ERP study.

Science.gov (United States)

Zhang, Jingjing; Zhou, Xuefeng; Chang, Ruohan; Yang, Yufang

2018-01-31

In real life, the processing of an incoming event is continuously influenced by prior information at multiple timescales. The present study investigated how harmonic contexts at both local and global levels influence the processing of an incoming chord in an event-related potentials experiment. Chord sequences containing two phrases were presented to musically trained listeners, with the last critical chord either harmonically related or less related to its preceding context at local and/or global levels. ERPs data showed an ERAN-like effect for local context in early time window and a N5-like component for later interaction between the local context and global context. These results suggest that both the local and global contexts influence the processing of an incoming music event, and the local effect happens earlier than the global. Moreover, the interaction between the local context and global context in N5 may suggest that music syntactic integration at local level takes place prior to the integration at global level. Copyright © 2017 Elsevier Ltd. All rights reserved.

Event-by-Event Simulation of Induced Fission

Energy Technology Data Exchange (ETDEWEB)

Vogt, R; Randrup, J

2007-12-13

We are developing a novel code that treats induced fission by statistical (or Monte-Carlo) simulation of individual decay chains. After its initial excitation, the fissionable compound nucleus may either deexcite by evaporation or undergo binary fission into a large number of fission channels each with different energetics involving both energy dissipation and deformed scission prefragments. After separation and Coulomb acceleration, each fission fragment undergoes a succession of individual (neutron) evaporations, leading to two bound but still excited fission products (that may further decay electromagnetically and, ultimately, weakly), as well as typically several neutrons. (The inclusion of other possible ejectiles is planned.) This kind of approach makes it possible to study more detailed observables than could be addressed with previous treatments which have tended to focus on average quantities. In particular, any type of correlation observable can readily be extracted from a generated set of events. With a view towards making the code practically useful in a variety of applications, emphasis is being put on making it numerically efficient so that large event samples can be generated quickly. In its present form, the code can generate one million full events in about 12 seconds on a MacBook laptop computer. The development of this qualitatively new tool is still at an early stage and quantitative reproduction of existing data should not be expected until a number of detailed refinement have been implemented.

Event-by-Event Simulation of Induced Fission

Science.gov (United States)

Vogt, Ramona; Randrup, Jørgen

2008-04-01

We are developing a novel code that treats induced fission by statistical (or Monte-Carlo) simulation of individual decay chains. After its initial excitation, the fissionable compound nucleus may either de-excite by evaporation or undergo binary fission into a large number of fission channels each with different energetics involving both energy dissipation and deformed scission pre-fragments. After separation and Coulomb acceleration, each fission fragment undergoes a succession of individual (neutron) evaporations, leading to two bound but still excited fission products (that may further decay electromagnetically and, ultimately, weakly), as well as typically several neutrons. (The inclusion of other possible ejectiles is planned.) This kind of approach makes it possible to study more detailed observables than could be addressed with previous treatments which have tended to focus on average quantities. In particular, any type of correlation observable can readily be extracted from a generated set of events. With a view towards making the code practically useful in a variety of applications, emphasis is being put on making it numerically efficient so that large event samples can be generated quickly. In its present form, the code can generate one million full events in about 12 seconds on a MacBook laptop computer. The development of this qualitatively new tool is still at an early stage and quantitative reproduction of existing data should not be expected until a number of detailed refinement have been implemented.

Event-by-Event Simulation of Induced Fission

International Nuclear Information System (INIS)

Vogt, Ramona; Randrup, Joergen

2008-01-01

We are developing a novel code that treats induced fission by statistical (or Monte-Carlo) simulation of individual decay chains. After its initial excitation, the fissionable compound nucleus may either de-excite by evaporation or undergo binary fission into a large number of fission channels each with different energetics involving both energy dissipation and deformed scission pre-fragments. After separation and Coulomb acceleration, each fission fragment undergoes a succession of individual (neutron) evaporations, leading to two bound but still excited fission products (that may further decay electromagnetically and, ultimately, weakly), as well as typically several neutrons. (The inclusion of other possible ejectiles is planned.) This kind of approach makes it possible to study more detailed observables than could be addressed with previous treatments which have tended to focus on average quantities. In particular, any type of correlation observable can readily be extracted from a generated set of events. With a view towards making the code practically useful in a variety of applications, emphasis is being put on making it numerically efficient so that large event samples can be generated quickly. In its present form, the code can generate one million full events in about 12 seconds on a MacBook laptop computer. The development of this qualitatively new tool is still at an early stage and quantitative reproduction of existing data should not be expected until a number of detailed refinement have been implemented

Event-by-Event Simulation of Induced Fission

International Nuclear Information System (INIS)

Vogt, R; Randrup, J

2007-01-01

We are developing a novel code that treats induced fission by statistical (or Monte-Carlo) simulation of individual decay chains. After its initial excitation, the fissionable compound nucleus may either deexcite by evaporation or undergo binary fission into a large number of fission channels each with different energetics involving both energy dissipation and deformed scission prefragments. After separation and Coulomb acceleration, each fission fragment undergoes a succession of individual (neutron) evaporations, leading to two bound but still excited fission products (that may further decay electromagnetically and, ultimately, weakly), as well as typically several neutrons. (The inclusion of other possible ejectiles is planned.) This kind of approach makes it possible to study more detailed observables than could be addressed with previous treatments which have tended to focus on average quantities. In particular, any type of correlation observable can readily be extracted from a generated set of events. With a view towards making the code practically useful in a variety of applications, emphasis is being put on making it numerically efficient so that large event samples can be generated quickly. In its present form, the code can generate one million full events in about 12 seconds on a MacBook laptop computer. The development of this qualitatively new tool is still at an early stage and quantitative reproduction of existing data should not be expected until a number of detailed refinement have been implemented

When unforeseen event become strategic

DEFF Research Database (Denmark)

Larsen, Mette Vinther; Rasmussen, Jørgen Gulddahl

2017-01-01

This article acknowledges that strategising processes revolve around allowing for continual shifts in an uncertain environment to constructively shape the ways in which managers strategise. The research question pursued in this article is: ‘How do unforeseen events shape managerial strategising......?’ The theoretical background for this article is inspired by research done within the strategy-as-practice and strategy-in-practice communities and uses concepts such as strategic intent, wayfinding/wayfaring and temporal work to explore how the managers from the small Danish Software Company cooperated with actors...... in the mining industry. This cooperation was initially perceived as an unforeseen event but, incrementally and retrospectively, it became strategic. The main theoretical and practice-anchored findings draw attention to the roles that unforeseen events can play in shaping strategising. These findings underline...

Method to Find Recovery Event Combinations in Probabilistic Safety Assessment

International Nuclear Information System (INIS)

Jung, Woo Sik; Riley, Jeff

2016-01-01

These research activities may develop mathematical methods, engineering analyses, and business processes. The research activities of the project covered by this scope are directed toward the specific issues of implementing the methods and strategies on a computational platform, identifying the features and enhancements to EPRI tools that would be necessary to realize significant improvements to the risk assessments performed by the end user. Fault tree analysis is extensively and successfully applied to the risk assessment of safety-critical systems such as nuclear, chemical and aerospace systems. The fault tree analysis is being used together with an event tree analysis in PSA of nuclear power plants. Fault tree solvers for a PSA are mostly based on the cutset-based algorithm. They generate minimal cut sets (MCSs) from a fault tree. The most popular fault tree solver in the PSA industry is FTREX. During the course of this project, certain technical issues (see Sections 2 to 5) have been identified that need to be addressed regarding how minimal cut sets are generated and quantified. The objective of this scope of the work was to develop new methods or techniques to address these technical limitations. By turning on all the cutset initiators (%1, %2, %3, %), all the possible minimal cut sets can be calculated easier than with the original fault tree. It is accomplished by the fact that the number of events in the minimal cut sets are significantly reduced by using cutset initiators instead of random failure events. And byy turning on a few chosen cutset initiators and turning off the other cutset initiators, minimal cut sets of the selected cutset initiator(s) can be easily calculated. As explained in the previous Sections, there is no way to calculate these minimal cut sets by turning off/on the random failure events in the original fault tree

Method to Find Recovery Event Combinations in Probabilistic Safety Assessment

Energy Technology Data Exchange (ETDEWEB)

Jung, Woo Sik [Sejong University, Seoul (Korea, Republic of); Riley, Jeff [Electric Power Research, Palo Alto (United States)

2016-05-15

These research activities may develop mathematical methods, engineering analyses, and business processes. The research activities of the project covered by this scope are directed toward the specific issues of implementing the methods and strategies on a computational platform, identifying the features and enhancements to EPRI tools that would be necessary to realize significant improvements to the risk assessments performed by the end user. Fault tree analysis is extensively and successfully applied to the risk assessment of safety-critical systems such as nuclear, chemical and aerospace systems. The fault tree analysis is being used together with an event tree analysis in PSA of nuclear power plants. Fault tree solvers for a PSA are mostly based on the cutset-based algorithm. They generate minimal cut sets (MCSs) from a fault tree. The most popular fault tree solver in the PSA industry is FTREX. During the course of this project, certain technical issues (see Sections 2 to 5) have been identified that need to be addressed regarding how minimal cut sets are generated and quantified. The objective of this scope of the work was to develop new methods or techniques to address these technical limitations. By turning on all the cutset initiators (%1, %2, %3, %), all the possible minimal cut sets can be calculated easier than with the original fault tree. It is accomplished by the fact that the number of events in the minimal cut sets are significantly reduced by using cutset initiators instead of random failure events. And byy turning on a few chosen cutset initiators and turning off the other cutset initiators, minimal cut sets of the selected cutset initiator(s) can be easily calculated. As explained in the previous Sections, there is no way to calculate these minimal cut sets by turning off/on the random failure events in the original fault tree.