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Sample records for lithiasis minimizing radiation

  1. [Cystine-lysinuric lithiasis].

    Science.gov (United States)

    Callís, L; Castelló, F; Vila, A; Pi Ferrer, A

    1978-01-01

    Cistin-lisinuria is not a unfrequent etiology of lithiasis in children. Six patients have been studied as well as their families, being a total of 45 patients. Lithiasis was present in ten of our patients, and hyperaminoaciduria, without lithiasis in ten, affecting in both cases (with or without litiasis) either all the four amynoacide (cystine, lysine, arginine and ornithine) or only one or two of them. Authors have not found any correlation between clearance of cystine and the presence or absence of lithiasis; on the other hand the best index to correlate the presence of lithiasis is to reach a value, equal or superior to 300 mgr of cystine excreted in the urine per 1 gr of creatinine excreted in urine. The correct treatment in cystinuric patients with lithiasis is to alcalize the urine maintaining a constant urinary pH between 7-8, giving a sufficient dose of sodium bicarbonate per os. In case of resistance to this treatment or if a great calculi is present, D-penicillamine would be an efficient treatment to disolve the calculi. These treatment when carried out under analytical control presents no problems or complications in their experience.

  2. Renal lithiasis and nutrition

    OpenAIRE

    Prieto Rafel M; Costa-Bauza Antonia; Grases Felix

    2006-01-01

    Abstract Renal lithiasis is a multifactorial disease. An important number of etiologic factors can be adequately modified trough diet, since it must be considered that the urine composition is directly related to diet. In fact, the change of inappropriate habitual diet patterns should be the main measure to prevent kidney stones. In this paper, the relation between different dietary factors (liquid intake, pH, calcium, phosphate, oxalate, citrate, phytate, urate and vitamins) and each type of...

  3. Renal lithiasis and nutrition.

    Science.gov (United States)

    Grases, Felix; Costa-Bauza, Antonia; Prieto, Rafel M

    2006-09-06

    Renal lithiasis is a multifactorial disease. An important number of etiologic factors can be adequately modified through diet, since it must be considered that the urine composition is directly related to diet. In fact, the change of inappropriate habitual diet patterns should be the main measure to prevent kidney stones. In this paper, the relation between different dietary factors (liquid intake, pH, calcium, phosphate, oxalate, citrate, phytate, urate and vitamins) and each type of renal stone (calcium oxalate monohydrate papillary, calcium oxalate monohydrate unattached, calcium oxalate dihydrate, calcium oxalate dihydrate/hydroxyapatite, hydroxyapatite, struvite infectious, brushite, uric acid, calcium oxalate/uric acid and cystine) is discussed.

  4. Renal lithiasis and nutrition

    Directory of Open Access Journals (Sweden)

    Prieto Rafel M

    2006-09-01

    Full Text Available Abstract Renal lithiasis is a multifactorial disease. An important number of etiologic factors can be adequately modified trough diet, since it must be considered that the urine composition is directly related to diet. In fact, the change of inappropriate habitual diet patterns should be the main measure to prevent kidney stones. In this paper, the relation between different dietary factors (liquid intake, pH, calcium, phosphate, oxalate, citrate, phytate, urate and vitamins and each type of renal stone (calcium oxalate monohydrate papillary, calcium oxalate monohydrate unattached, calcium oxalate dihydrate, calcium oxalate dihydrate/hydroxyapatite, hydroxyapatite, struvite infectious, brushite, uric acid, calcium oxalate/uric acid and cystine is discussed.

  5. Minimizing radiation exposure during percutaneous nephrolithotomy.

    Science.gov (United States)

    Chen, T T; Preminger, G M; Lipkin, M E

    2015-12-01

    Given the recent trends in growing per capita radiation dose from medical sources, there have been increasing concerns over patient radiation exposure. Patients with kidney stones undergoing percutaneous nephrolithotomy (PNL) are at particular risk for high radiation exposure. There exist several risk factors for increased radiation exposure during PNL which include high Body Mass Index, multiple access tracts, and increased stone burden. We herein review recent trends in radiation exposure, radiation exposure during PNL to both patients and urologists, and various approaches to reduce radiation exposure. We discuss incorporating the principles of As Low As reasonably Achievable (ALARA) into clinical practice and review imaging techniques such as ultrasound and air contrast to guide PNL access. Alternative surgical techniques and approaches to reducing radiation exposure, including retrograde intra-renal surgery, retrograde nephrostomy, endoscopic-guided PNL, and minimally invasive PNL, are also highlighted. It is important for urologists to be aware of these concepts and techniques when treating stone patients with PNL. The discussions outlined will assist urologists in providing patient counseling and high quality of care.

  6. [Renal transplantation and urinary lithiasis].

    Science.gov (United States)

    Lechevallier, E; Saussine, C; Traxer, O

    2008-12-01

    Renal lithiasis in renal donors is rare. A renal stone in a donor, or in a renal transplant, is not a contraindication for harvesting nor transplantation. If possible, the stone must be removed at the time of the transplantation. The risk of lithiasis is increased in the renal transplant recipient, with a frequency of 2-6%. Metabolic abnormalities for lithiasis are frequent and can be induced by the immunosuppressive treatment, anticalcineurins. Lithiasis can have a poor prognosis in the renal recipient with a risk for infection or renal dysfunction. Small (renal transplant can be followed-up. Stones of 0.5-1.5cm need an extracorporeal lithotripsy with a previous safety JJ stent. Stones greater than 1.5cm can be treated by ureteroscopy or percutaneous surgery.

  7. Endoscopic Treatment of Studer's Orthotopic Neobladder Lithiasis

    Science.gov (United States)

    Gil-Sousa, Diogo; Oliveira-Reis, Daniel; Cavadas, Vitor; Oliveira, Manuel; Soares, José; Fraga, Avelino

    2015-01-01

    Studer's neobladder lithiasis is a rare but important long term complication of this orthotopic bladder substitute technique. We report a case of a 45 year-old male patient, submitted to a radical cystoprostatectomy with a Studer's orthotopic neobladder 4 years before, presenting bad compliance to recommended urinary habits, increased production of mucus and high post voiding residue. CT scan and urethrocystography showed a distended pouch with 2 major sacculations with narrow communication and a stone in each sacculation. A minimally invasive endoscopic technique was successfully used in the treatment of the 2 small calculus. PMID:26793507

  8. Endoscopic Treatment of Studer's Orthotopic Neobladder Lithiasis

    Directory of Open Access Journals (Sweden)

    Diogo Gil-Sousa

    2015-05-01

    Full Text Available Studer's neobladder lithiasis is a rare but important long term complication of this orthotopic bladder substitute technique. We report a case of a 45 year-old male patient, submitted to a radical cystoprostatectomy with a Studer's orthotopic neobladder 4 years before, presenting bad compliance to recommended urinary habits, increased production of mucus and high post voiding residue. CT scan and urethrocystography showed a distended pouch with 2 major sacculations with narrow communication and a stone in each sacculation. A minimally invasive endoscopic technique was successfully used in the treatment of the 2 small calculus.

  9. Radiation oncology: physics advances that minimize morbidity.

    Science.gov (United States)

    Allison, Ron R; Patel, Rajen M; McLawhorn, Robert A

    2014-12-01

    Radiation therapy has become an ever more successful treatment for many cancer patients. This is due in large part from advances in physics including the expanded use of imaging protocols combined with ever more precise therapy devices such as linear and particle beam accelerators, all contributing to treatments with far fewer side effects. This paper will review current state-of-the-art physics maneuvers that minimize morbidity, such as intensity-modulated radiation therapy, volummetric arc therapy, image-guided radiation, radiosurgery and particle beam treatment. We will also highlight future physics enhancements on the horizon such as MRI during treatment and intensity-modulated hadron therapy, all with the continued goal of improved clinical outcomes.

  10. Study on technology for minimizing radiation risk

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Ho; Kim, In Gyu; Kim, Jin Kyu; Lee, Kang Suk; Kim, Kug Chan; Chun, Ki Chung

    1997-01-01

    Apoptosis, also called programmed cell death to discriminate it from necrosis, is characterized by : chromatin condensation, apoptotic body formation, fragmentation of DNA into oligonucleosome sized pieces, swelling and progressive cell degradation. We examined morphological and biochemical changes of T-lymphocytes following gamma irradiation exposure. The results are followings. (1) Murine lymphocytes have several characteristics : The irradiated cells undergo morphological and biochemical changes characteristic of apoptosis, causing growth delay. (0.01, 0.1, 1.0 Gy) (2) The onset of DNA fragmentation in cells occurs after one more cell divisions. (3) DNA fragmentation in cells occurs in all irradiated group (0.1, 1.0, 2.0, 4.0 Gy, 24 hours following gamma radiation exposure) (4) Apoptotic bodies were detected by confocal microscope with ease when compared with electron microscope. For the developing technology for minimizing radiation damage, the following experimental works have been done. (1) Establishment of experimental system for pre-screening of radioprotectants - Screening of protective substances using TSH bioindicator - Efficacy test of some radioprotective materials (2) TSH bioindicator system can make a scientific role in screening unknown materials for their possible radioprotective effect. (author). 42 refs., 3 tabs., 9 figs.

  11. Radiative Neutrino Mass via Both Minimal Dark Matter Candidates

    CERN Document Server

    Ahriche, Amine; Nasri, Salah; Picek, Ivica

    2016-01-01

    We identify a minimal model achieving one-loop radiative neutrino masses due to couplings with dark matter. Interestingly the model contains both the quintuplet fermion and the septuplet scalar identified as minimal dark matter candidates by Cirelli, Fornengo and Strumia - it gives radiative neutrino mass due to both minimal dark matter candidates. The model is related to those proposed in a recent work (dubbed minimal R$\

  12. [Current treatment of ureteral lithiasis].

    Science.gov (United States)

    Reina Ruiz, C; Quintero Rodríguez, R; Espinosa Olmedo, J; Arrabal Martín, M; Campoy Martínez, P; Salazar Murillo, R; García Pérez, M

    1995-01-01

    The treatment of ureteral lithiasis has undergone a revolution since the arrival of new techniques offering different therapeutical choices for which time is gradually elucidating the indications for each of the new procedures; although, to a large extent, a degree of controversy still persists. This paper reviews the different methods for ureteral lithiasis; spontaneous ejection and medical treatment, surgery, early endoscopic manoeuvres, backward and forward urethroscopy and, finally, extracorporeal lithority. This therapeutical experience in 3 series of ureteral lithiasis addressed with different criteria are revised together with 182 obstructive calculi of the lumbar ureter. We believe that grading the ureteral calculi according to their anatomical and functional features improves the results, since improved adjustment can be achieved for the indications of the various methods. Also it is noted that support endourology for extracorporeal lithotrity does not improve the results of treatment in lumbar calculi under 2 cm, and therefore our current approach is towards "in situ" treatment without complementary manoeuvres. Finally we show the therapeutic algorithm we are following actually to manage ureteral litiasis.

  13. Studies on the strategies of minimizing radiation damage

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Hee Yong; Sohn, Young Sook

    1998-04-01

    We studied on the strategies of minimizing radiation damage in animal system. To this end we studied following areas of research (1) mechanisms involved in bone marrow damage after total body irradiation, (2) extraction of components that are useful in protecting hematopoietic system from radiation damage, (3) cell therapy approach in restoring the damaged tissue, (4) development of radioprotective chemical reagent, and (5) epidemiological study on the population that had been exposed to radiation.

  14. Boosted Decision Trees for Lithiasis Type Identification

    Directory of Open Access Journals (Sweden)

    Boutalbi Rafika

    2015-06-01

    Full Text Available Several urologic studies showed that it was important to determine the lithiasis types, in order to limit the recurrence residive risk and the renal function deterioration. The difficult problem posed by urologists for classifying urolithiasis is due to the large number of parameters (components, age, gender, background ... taking part in the classification, and hence the probable etiology determination. There exist 6 types of urinary lithiasis which are distinguished according to their compositions (chemical components with given proportions, their etiologies and patient profile. This work presents models based on Boosted decision trees results, and which were compared according to their error rates and the runtime. The principal objectives of this work are intended to facilitate the urinary lithiasis classification, to reduce the classification runtime and an epidemiologic interest. The experimental results showed that the method is effective and encouraging for the lithiasis type identification.

  15. Boosted Decision Trees for Lithiasis Type Identification

    OpenAIRE

    Boutalbi Rafika; Farah Nadir; Chitibi Kheir Eddine; Boutefnouchet; Tanougast Camel

    2015-01-01

    Several urologic studies showed that it was important to determine the lithiasis types, in order to limit the recurrence residive risk and the renal function deterioration. The difficult problem posed by urologists for classifying urolithiasis is due to the large number of parameters (components, age, gender, background ...) taking part in the classification, and hence the probable etiology determination. There exist 6 types of urinary lithiasis which are distinguished according to their comp...

  16. [Lithiasis and ectopic pelvic kidney. Therapeutic aspects].

    Science.gov (United States)

    Aboutaieb, R; Rabii, R; el Moussaoui, A; Joual, A; Sarf, I; el Mrini, M; Benjelloun, S

    1996-01-01

    Kidney in ectopic position is dysplasic, and associated to other malformations. The advent of a lithiasis in these conditions rises questions about therapeutic options. We report on five observations of pelvic ectopic kidney with urinary lithiasis. Patients were aged from 16 to 42 years. Kidney was non functional in two cases, or with normal appearance sized 10 to 12 cm. We performed total nephrectomy in two cases, pyelolithotomy in the other cases. Surgical approach was subperitoneal via iliac route. A dismembered pyeloplasty was associated in one case. All patients did well. Radiologic control at 6 and 12 months showed no recurrence in a well functioning kidney. Surgical lithotomy is advocated as a treatment in urinary lithiasis affecting ectopic kidney. It is an easy procedure which permits correction of other associated malformations.

  17. Minimal length, maximal momentum and thermodynamics of black body radiation

    CERN Document Server

    Shababi, Homa

    2013-01-01

    In this paper we study thermodynamics of black body radiation in the presence of quantum gravitational effects through a Generalized Uncertainty Principle that admits both a minimal measurable length and a maximal momentum. We focus on quantum gravity induced modifications of thermodynamical quantities in this framework. Some important issues such as the generalized Planck distribution, Wien s law and Dulong Petit law are studied in this setup with details.

  18. Closing in on minimal dark matter and radiative neutrino masses

    CERN Document Server

    Sierra, D Aristizabal; Wegman, D

    2016-01-01

    We study one-loop radiative neutrino mass models in which one of the beyond-the-standard model fields is either a hypercharge-zero fermion quintet (minimal dark matter) or a hypercharge-zero scalar septet. By systematically classifying all possible one-loop such models we identify various processes that render the neutral component of these representations (dark matter) cosmologically unstable. Thus, our findings show that these scenarios are in general not reconcilable with dark matter stability unless tiny couplings or additional ad hoc symmetries are assumed, in contrast to minimal dark matter models where stability is entirely due to the standard model gauge symmetry. For some variants based on higher order loops we find that $\\alpha_2$ reaches a Landau pole at rather low scales, typically comparable to the characteristic scale of the model itself. Thus, we argue that some of these variations although consistent with dark matter stability and phenomenological constraints are hard to reconcile with perturb...

  19. Radiation processing of minimally processed vegetables and aromatic plants

    Energy Technology Data Exchange (ETDEWEB)

    Trigo, M.J. [Instituto Nacional dos Recursos Biologicos, L-INIA, Quinta do Marques, 2784-505 Oeiras (Portugal)], E-mail: mjptrigo@gmail.com; Sousa, M.B.; Sapata, M.M.; Ferreira, A.; Curado, T.; Andrada, L. [Instituto Nacional dos Recursos Biologicos, L-INIA, Quinta do Marques, 2784-505 Oeiras (Portugal); Botelho, M.L. [Instituto Tecnologico e Nuclear, E.N. 10, 2696 Sacavem (Portugal); Veloso, M.G. [Faculdade de Medicina Veterinaria de Lisboa, Av. da Universidade Tecnica, Alto da Ajuda, 1300-477 Lisboa (Portugal)

    2009-07-15

    Vegetables are an essential part of people's diet all around the world. Due to cultivate techniques and handling after harvest, these products, may contain high microbial load that can cause food borne outbreaks. The irradiation of minimally processed vegetables is an efficient way to reduce the level of microorganisms and to inhibit parasites, helping a safe global trade. Evaluation of the irradiation's effects was carried out in minimal processed vegetables, as coriander (Coriandrum sativum L.), mint (Mentha spicata L.), parsley (Petroselinum crispum Mill, (A.W. Hill)), lettuce (Lactuca sativa L.) and watercress (Nasturium officinale L.). The inactivation level of natural microbiota and the D{sub 10} values of Escherichia coli O157:H7 and Listeria innocua in these products were determined. The physical-chemical and sensorial characteristics before and after irradiation at a range of 0.5 up to 2.0 kGy applied doses were also evaluated. No differences were verified in the overall of sensorial and physical properties after irradiation up to 1 kGy, a decrease of natural microbiota was noticed ({>=}2 log). Based on the determined D{sub 10}, the amount of radiation necessary to kill 10{sup 5}E. coli and L. innocua was between 0.70 and 1.55 kGy. Shelf life of irradiated coriander, mint and lettuce at 0.5 kGy increased 2, 3 and 4 days, respectively, when compared with non-irradiated.

  20. Radiation processing of minimally processed vegetables and aromatic plants

    Science.gov (United States)

    Trigo, M. J.; Sousa, M. B.; Sapata, M. M.; Ferreira, A.; Curado, T.; Andrada, L.; Botelho, M. L.; Veloso, M. G.

    2009-07-01

    Vegetables are an essential part of people's diet all around the world. Due to cultivate techniques and handling after harvest, these products, may contain high microbial load that can cause food borne outbreaks. The irradiation of minimally processed vegetables is an efficient way to reduce the level of microorganisms and to inhibit parasites, helping a safe global trade. Evaluation of the irradiation's effects was carried out in minimal processed vegetables, as coriander ( Coriandrum sativum L .), mint ( Mentha spicata L.), parsley ( Petroselinum crispum Mill, (A.W. Hill)), lettuce ( Lactuca sativa L.) and watercress ( Nasturium officinale L.). The inactivation level of natural microbiota and the D 10 values of Escherichia coli O157:H7 and Listeria innocua in these products were determined. The physical-chemical and sensorial characteristics before and after irradiation at a range of 0.5 up to 2.0 kGy applied doses were also evaluated. No differences were verified in the overall of sensorial and physical properties after irradiation up to 1 kGy, a decrease of natural microbiota was noticed (⩾2 log). Based on the determined D10, the amount of radiation necessary to kill 10 5E. coli and L. innocua was between 0.70 and 1.55 kGy. Shelf life of irradiated coriander, mint and lettuce at 0.5 kGy increased 2, 3 and 4 days, respectively, when compared with non-irradiated.

  1. Metabolic assessment in patients with urinary lithiasis

    Directory of Open Access Journals (Sweden)

    Carmen R. Amaro

    2005-02-01

    Full Text Available INTRODUCTION: Metabolic investigation in patients with urinary lithiasis is very important for preventing recurrence of disease. The objective of this work was to diagnose and to determine the prevalence of metabolic disorders, to assess the quality of the water consumed and volume of diuresis as potential risk factors for this pathology. PATIENTS AND METHODS: We studied 182 patients older than 12 years. We included patients with history and/or imaging tests confirming at least 2 stones, with creatinine clearance > 60 mL/min and negative urine culture. The protocol consisted in the collection of 2, 24-hour urine samples, for dosing Ca, P, uric acid, Na, K, Mg, Ox and Ci, glycemia and serum levels of Ca, P, Uric acid, Na, K, Cl, Mg, U and Cr, urinary pH and urinary acidification test. RESULTS: 158 patients fulfilled the inclusion criteria. Among these, 151 (95.5% presented metabolic changes, with 94 (62.2% presenting isolated metabolic change and 57 (37.8% had mixed changes. The main disorders detected were hypercalciuria (74%, hypocitraturia (37.3%, hyperoxaluria (24.1%, hypomagnesuria (21%, hyperuricosuria (20.2%, primary hyperparathyroidism (1.8% secondary hyperparathyroidism (0.6% and renal tubular acidosis (0.6. CONCLUSION: Metabolic change was diagnosed in 95.5% of patients. These results warrant the metabolic study and follow-up in patients with recurrent lithiasis in order to decrease the recurrence rate through specific treatments, modification in alimentary and behavioral habits.

  2. Epididymal lithiasis in Gallus gallus domesticus

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    JM Rocha Jr.

    2009-03-01

    Full Text Available A study on the occurrence of epididymal lithiasis (EL in Gallus gallus domesticus of different breeds and from different geographical regions of Brazil was carried out. Forty breeding roosters were collected in the states Santa Catarina, São Paulo, Minas Gerais, Espírito Santo and Goiás, representing two specific pathogen free Leghorn lines (SPF, one commercial Leghorn layer breeder (Hy-Line line, two commercial broiler breeder lines (Ross and Cobb, and two backyard chicken flocks. In commercial poultry breeders, EL was observed mainly after 55 weeks of age, and lithus resulted in lower fertility caused by inadequate maturation of spermatozoa and testicular atrophy, which evolved to more severe testicular dysfunction at 100 weeks of age. One hundred percent of the sampled roosters of the evaluated SPF lines presented epididymal lithiasis, which was also observed in all commercial genetic lines. The analysis of EL occurrence revealed no differences among regions and breeds: all regions and genetic lines presented epididymal calculi and the occurrence seemed higher in the more intensively-reared chickens. As for the backyard roosters, 50% presented calculi. Considering the occurrence of EL in the SPF flocks, its primary association with infectious bronchitis virus (IBV infection was discarded, despite its contribution to fertility loss.

  3. [Meningeal tuberculosis and renal lithiasis. A case report].

    Science.gov (United States)

    Benabdellah, A; Attar, A; Maalem, A; Bekkhoucha, S

    2002-01-01

    Urinary tuberculosis is frequent in Algeria. The discovery of the disease become difficult when one of the three criterium of the diagnostic does not allow a diagnosis of certitude. The authors reported the case of a 44 years-old patient admitted to hospital for tuberculous meningitis recovery from left nephrectomy for urinary lithiasis. The histology does not find specific lesions. Then, no antituberculous treatment is prescribed. The patient has developed renal and meningitis tuberculosis associated with urinary lithiasis. Koch's bacillus is found in the urine. The evolution under medical treatment was excellent. The urinary lithiasis has hided tuberculosis and the discovery of the disease was late.

  4. Minimizing and communicating radiation risk in pediatric nuclear medicine.

    Science.gov (United States)

    Fahey, Frederic H; Treves, S Ted; Adelstein, S James

    2012-03-01

    The value of pediatric nuclear medicine is well established. Pediatric patients are referred to nuclear medicine from nearly all pediatric specialties including urology, oncology, cardiology, gastroenterology, and orthopedics. Radiation exposure is associated with a potential, small, risk of inducing cancer in the patient later in life and is higher in younger patients. Recently, there has been enhanced interest in exposure to radiation from medical imaging. Thus, it is incumbent on practitioners of pediatric nuclear medicine to have an understanding of dosimetry and radiation risk to communicate effectively with their patients and their families. This article reviews radiation dosimetry for radiopharmaceuticals and also CT given the recent proliferation of PET/CT and SPECT/CT. It also describes the scientific basis for radiation risk estimation in the context of pediatric nuclear medicine. Approaches for effective communication of risk to patients' families are discussed. Lastly, radiation dose reduction in pediatric nuclear medicine is explicated.

  5. Minimalism

    CERN Document Server

    Obendorf, Hartmut

    2009-01-01

    The notion of Minimalism is proposed as a theoretical tool supporting a more differentiated understanding of reduction and thus forms a standpoint that allows definition of aspects of simplicity. This book traces the development of minimalism, defines the four types of minimalism in interaction design, and looks at how to apply it.

  6. Minimally Invasive Radiation Biodosimetry and Evaluation of Organ Responses

    Science.gov (United States)

    2016-10-01

    been optimized. miR- Rad Development Plan Discovery: human clinical trial samples Evaluate: miRNA changes after targeted radiation-mice Test: miRNA...topic of the study is “Illnesses Related to Radiation Exposure”. The focus of the work is to develop circulating miRNAs as radiation biodosimeters for... rapid triage in radiological events. The warfighters and military personnel deployed to the field as emergency responders in the aftermath of

  7. Virtual reality application for simulating and minimizing worker radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Ki Doo [Korea Hydro and Nuclear Power Co., Taejon (Korea, Republic of); Hajek, Brian K. [Ohio State University, columbus (United States); Lee, Yon Sik [Kunsan National University, Kunsan (Korea, Republic of); Shin, Yoo Jin [Kwangwoon University, Seoul (Korea, Republic of)

    2004-07-01

    To plan work and preclude unexpected radiation exposures in a nuclear power plant, a virtual nuclear plant is a good solution. For this, there are prerequisites such as displaying real time radiation exposure data onto an avatar and preventing speed reduction caused by multiple users on the net-based system. The work space is divided into several sections and radiation information is extracted section by section. Based on the simulation algorithm, real time processing is applied to the events and movements of the avatar. Because there are millions of parts in a nuclear power plant, it is almost impossible to model all of them. Several parts of virtual plant have been modeled using 3D internet virtual reality for the model development. Optimum one-click Active-X is applied for the system, which provides easy access to the virtual plant. Connection time on the net is 20-30 sec for initial loading and 3-4 sec for the 2nd and subsequent times.

  8. Radiative Seesaw in Minimal 3-3-1 Model

    CERN Document Server

    Okada, Hiroshi; Orikasa, Yuta

    2015-01-01

    We study the neutrino sector in a minimal $SU(3)_L\\times U(1)_X$ model, in which its mass is generated at one-loop level with the charged lepton mass, and hence there exists a strong correlation between the charged-lepton mass and the neutrino mass. We identify the parameter region of this model to satisfy the current neutrino oscillation data as well as the constraints on lepton flavor violating processes. We also discuss a possibility to explain the muon anomalous magnetic moment.

  9. [Effect of environmental and individual factors in renal lithiasis].

    Science.gov (United States)

    Vasilescu, L; Ciochină, Al D; Corciovă, C

    2011-01-01

    The large number of cases with renal lithiasis occurring in the population of the south-east region of Iasi county has determined us to make a study in this region for the identification of environmental and individual factors involved in the etiopathogenesis of this disease. This study is performed to assert the corelation between the clinical and paraclinical patients data with those obtained through water and soil chemical analisys for identification of determinant environmental and individual factors involved in etiopathogenesis of this disease. This study indicates that the environment factors (water, soil) correlated with personal factors, especially the diet and standard of living are the favouring factors of renal lithiasis.

  10. Effectiveness of radiation processing for elimination of Salmonella Typhimurium from minimally processed pineapple (Ananas comosus Merr.).

    Science.gov (United States)

    Shashidhar, Ravindranath; Dhokane, Varsha S; Hajare, Sachin N; Sharma, Arun; Bandekar, Jayant R

    2007-04-01

    The microbiological quality of market samples of minimally processed (MP) pineapple was examined. The effectiveness of radiation treatment in eliminating Salmonella Typhimurium from laboratory inoculated ready-to-eat pineapple slices was also studied. Microbiological quality of minimally processed pineapple samples from Mumbai market was poor; 8.8% of the samples were positive for Salmonella. D(10) (the radiation dose required to reduce bacterial population by 90%) value for S. Typhimurium inoculated in pineapple was 0.242 kGy. Inoculated pack studies in minimally processed pineapple showed that the treatment with a 2-kGy dose of gamma radiation could eliminate 5 log CFU/g of S. Typhimurium. The pathogen was not detected from radiation-processed samples up to 12 d during storage at 4 and 10 degrees C. The processing of market samples with 1 and 2 kGy was effective in improving the microbiological quality of these products.

  11. [Gallstone obstruction of the common bile duct, a severe form of biliary lithiasis. Choice of treatment].

    Science.gov (United States)

    Le Neel, J C; Guiberteau, B; Kohen, M; Borde, L; Sartre, J Y; Bourseau, J C

    1992-01-01

    Collection of 10 or more stones in the extrahepatic common bile duct causes lithiasic obstruction of the CBD, a fairly rare entity observed in less than 10% of cases of bile duct lithiasis. This study is based on 35 cases recorded over 10 years, including 60% in patients aged more than 75 years. Endoscopic treatment was attempted in 28% of patients and was totally successful in one case our of four only because of insufficient removal of obstruction after sphincterotomy. Surgery, either necessary (8 cases) or systematic (25 cases) combines cholecystectomy, choledocotomy and biliary fiberendoscopy for a complete treatment minimizing the risks of residual lithiasis. While biliodigestive anastomoses prevailed (58%) during the first years of this study, external biliary drainage was most often chosen during the last 5 years. This surgery in aged patients still entails high morbidity (25%) and considerable mortality (9%). Better efficacy may be provided in the future by the combination of fiberendoscopic means and of lithotrity for aged subjects at high surgical risks.

  12. [Percutaneous Nephrolithotripsy for Renal Transplant Lithiasis: A Case Report].

    Science.gov (United States)

    Oida, Takeshi; Kanemitsu, Toshiyuki; Hayashi, Tetsuya; Fujimoto, Nobumasa; Koide, Takuo

    2016-02-01

    A 54-year-old man was introduced to our hospital for follow-up examinations after renal transplantation. At the initial visit, a 25 mm renal transplant stone was noted, which had enlarged to 32 mm at an examination 1 year later. We first attempted transurethral lithotripsy (TUL), but failed due to ureteral stricture. However, we could completely remove the stone in 2 sessions of percutaneous nephrolithotripsy (PNL). The incidence of urinary lithiasis after renal transplantation ranges from 0.17-1.8%, for which PNL and TUL are frequently used. Although considered to be accompanied with risks of bleeding, bowel injury, and renal dysfunction, PNL is effective for urinary lithiasis after renal transplantation. TUL is less invasive, but access may be difficult when the ureter has an unusual course or ureteral stricture exists, as in our patient.

  13. [Cystinic lithiasis. Current aspects of the urologic treatment].

    Science.gov (United States)

    Dore, B; Irani, J; Marroncle, M; Aubert, J

    1990-01-01

    On the basis of a series of 9 patients (12 renal units) gathered over 19 years, the authors analyze the current possibilities of treatment of cystine lithiasis. They first describe the characteristics of this litiasis, which is rare but serious, being naturally prone to recurrence because it is caused by a genetic defect. The development of extracorporeal lithotripsy raised great hopes for the treatment of this lithiasis, but it was soon realized that cystine strones were hard to break. However, even the mere fragmentation of the stones improves the dissolving action of the various drugs proposed to modify the pH of urine. The authors consider that open surgery by means of posterior vertical lumbar section still is indicated for larger stones, and percutaneous nephrolithotomy seems to be a very useful technique, either exclusively or as a complement of extracorporeal lithotrity.

  14. Kinetic versus thermodynamic factors in calcium renal lithiasis.

    Science.gov (United States)

    Grases, F; Costa-Bauzá, A; Königsberger, E; Königsberger, L C

    2000-01-01

    Calcium renal lithiasis formation depends on the balance between thermodynamic (supersaturation) and kinetic (inhibitors, nucleants) factors. In this paper, the importance of both groups was evaluated using (a) the complete urine analysis data obtained from 32 healthy volunteers and 141 active stone-formers, and (b) a comprehensive computer model to calculate the supersaturation values of calcium oxalate monohydrate, hydroxyapatite and brushite in each urine sample. The results of this evaluation were used to assess the possible effectiveness of a given pharmacological treatment.

  15. Percutaneous Nephrolithotripsy for Renal Transplant Lithiasis : A Case Report

    OpenAIRE

    種田, 建史; 金光, 俊行; 林, 哲也; 藤本, 宜正; 小出, 卓生

    2016-01-01

    A 54-year-old man was introduced to our hospital for follow-up examinations after renal transplantation. At the initial visit, a 25 mm renal transplant stone was noted, which had enlarged to 32 mm at an examination 1 year later. We first attempted transurethral lithotripsy (TUL), but failed due to ureteral stricture. However, we could completely remove the stone in 2 sessions of percutaneous nephrolithotripsy (PNL). The incidence of urinary lithiasis after renal transplantation ranges from 0....

  16. Calcium renal lithiasis: metabolic diagnosis and medical treatment

    OpenAIRE

    Miguel Angel Arrabal-Polo; Miguel Arrabal-Martin; Juan Garrido-Gomez

    2013-01-01

    Calcium renal lithiasis is a frequent condition that affects the worldwide population and has a high recurrence rate. Different metabolic changes may trigger the onset of calcium stone disorders, such as hypercalciuria, hyperoxaluria, hyperuricosuria, hypocitraturia and others. There are also other very prevalent disorders that are associated with calcium calculi, such as arterial hypertension, obesity and loss of bone mineral density. A correct diagnosis needs to be obtained through examinin...

  17. Calcium renal lithiasis: metabolic diagnosis and medical treatment

    Directory of Open Access Journals (Sweden)

    Miguel Angel Arrabal-Polo

    Full Text Available Calcium renal lithiasis is a frequent condition that affects the worldwide population and has a high recurrence rate. Different metabolic changes may trigger the onset of calcium stone disorders, such as hypercalciuria, hyperoxaluria, hyperuricosuria, hypocitraturia and others. There are also other very prevalent disorders that are associated with calcium calculi, such as arterial hypertension, obesity and loss of bone mineral density. A correct diagnosis needs to be obtained through examining the serum and urinary parameters of mineral metabolism in order to carry out adequate prevention and treatment of this condition. Once the metabolic diagnosis is known, it is possible to establish dietary and pharmacological treatment that may enable monitoring of the disease and prevent recurrence of stone formation. Some advances in treating this pathological condition have been made, and these include use of sodium alendronate in patients with calcium renal lithiasis and osteopenia/osteoporosis, or use of a combination of a thiazide with a bisphosphonate. In summary, calcium renal lithiasis often requires multidrug treatment with strict control and follow-up of patients.

  18. Calcium renal lithiasis: metabolic diagnosis and medical treatment.

    Science.gov (United States)

    Arrabal-Polo, Miguel Angel; Arrabal-Martin, Miguel; Garrido-Gomez, Juan

    2013-01-01

    Calcium renal lithiasis is a frequent condition that affects the worldwide population and has a high recurrence rate. Different metabolic changes may trigger the onset of calcium stone disorders, such as hypercalciuria, hyperoxaluria, hyperuricosuria, hypocitraturia and others. There are also other very prevalent disorders that are associated with calcium calculi, such as arterial hypertension, obesity and loss of bone mineral density. A correct diagnosis needs to be obtained through examining the serum and urinary parameters of mineral metabolism in order to carry out adequate prevention and treatment of this condition. Once the metabolic diagnosis is known, it is possible to establish dietary and pharmacological treatment that may enable monitoring of the disease and prevent recurrence of stone formation. Some advances in treating this pathological condition have been made, and these include use of sodium alendronate in patients with calcium renal lithiasis and osteopenia/osteoporosis, or use of a combination of a thiazide with a bisphosphonate. In summary, calcium renal lithiasis often requires multidrug treatment with strict control and follow-up of patients.

  19. Segmentation of Synchrotron Radiation micro-Computed Tomography Images using Energy Minimization via Graph Cuts

    Energy Technology Data Exchange (ETDEWEB)

    Meneses, Anderson A.M. [Federal University of Western Para (Brazil); Physics Institute, Rio de Janeiro State University (Brazil); Giusti, Alessandro [IDSIA (Dalle Molle Institute for Artificial Intelligence), University of Lugano (Switzerland); Almeida, Andre P. de, E-mail: apalmeid@gmail.com [Physics Institute, Rio de Janeiro State University (Brazil); Nuclear Engineering Program, Federal University of Rio de Janeiro (Brazil); Nogueira, Liebert; Braz, Delson [Nuclear Engineering Program, Federal University of Rio de Janeiro (Brazil); Almeida, Carlos E. de [Radiological Sciences Laboratory, Rio de Janeiro State University (Brazil); Barroso, Regina C. [Physics Institute, Rio de Janeiro State University (Brazil)

    2012-07-15

    The research on applications of segmentation algorithms to Synchrotron Radiation X-Ray micro-Computed Tomography (SR-{mu}CT) is an open problem, due to the interesting and well-known characteristics of SR images, such as the phase contrast effect. The Energy Minimization via Graph Cuts (EMvGC) algorithm represents state-of-art segmentation algorithm, presenting an enormous potential of application in SR-{mu}CT imaging. We describe the application of the algorithm EMvGC with swap move for the segmentation of bone images acquired at the ELETTRA Laboratory (Trieste, Italy). - Highlights: Black-Right-Pointing-Pointer Microstructures of Wistar rats' ribs are investigated with Synchrotron Radiation {mu}CT imaging. Black-Right-Pointing-Pointer The present work is part of a research on the effects of radiotherapy on the thoracic region. Black-Right-Pointing-Pointer Application of the Energy Minimization via Graph Cuts algorithm for segmentation is described.

  20. Minimizing incisional dehiscence following 2-stage prosthetic breast reconstruction in the setting of radiation therapy

    OpenAIRE

    Nahabedian, Maurice Y.

    2013-01-01

    Incisional dehiscence is a potential complication following prosthetic breast reconstruction. This is exacerbated in the setting of previous radiation therapy (RT) at the time of exchange of the tissue expander to a permanent implant. A technical modification is described that has successfully minimized this adverse event. Twenty-nine patients that had tissue expanders and RT underwent exchange of the device through a laterally based incision along the inframammary fold (IMF) rather than thro...

  1. Minimally processed mixed salad submitted to gamma radiation: effects on bioactive compounds

    Energy Technology Data Exchange (ETDEWEB)

    Hirashima, Fabiana K.; Sabato, Susy F., E-mail: fmayumi@usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Lanfer-Marquez, Ursula M., E-mail: lanferum@usp.br [Universidade de Sao Paulo (FCF/USP), Sao Paulo, SP (Brazil). Faculdade de Ciencias Farmaceuticas. Dept. de Alimentos e Nutricao Experimental

    2015-07-01

    High consumption of fruits and vegetables has been associated with a lowered incidence of oxidative stress-related diseases due to the presence of bioactive structures. Minimally processed products are a growing segment in food retail establishments because it is associated with practicality and convenience without significantly altering fresh-like characteristics. Low-dose of gamma radiation in combination with minimal processes has shown to be a promising strategy for extending shelf life and maintaining the organoleptic quality of fruits and vegetables. The objective of this study was to evaluate the levels of phenolic compounds, flavonoids, proanthocyanidins and antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl (DPPH•) free radical scavenging and Oxygen Radical Absorbance Capacity (ORAC) method in minimally processed mixed salad before and after different radiation doses. Samples of minimally processed mixed salad (with green and red cabbage and carrot) were purchased at local supermarket and irradiated with doses of 0.5, 1.0, 2.0 and 3.0 kGy. Phenolic compounds, flavonoids, proanthocyanidins and antioxidant activity by DPPH• and ORAC were analyzed on the same extract prepared with MeOH. The results showed that bioactive compounds levels and antioxidant activity decreased significantly (p<0.05) with an increasing on radiation dose. Gamma-rays may affect these compounds and can cause degradation or oxidation, which can explain the drop on levels. Although the radiation has affected the bioactive contents, the process seems to be interesting to maintaining organoleptic characteristics and provide microbiological security at doses up to 2.0 kGy, according to studies conducted by our research group. (author)

  2. Gamma radiation in the reduction of S almonella spp. inoculated on minimally processed watercress ( Nasturtium officinalis)

    Science.gov (United States)

    Martins, C. G.; Behrens, J. H.; Destro, M. T.; Franco, B. D. G. M.; Vizeu, D. M.; Hutzler, B.; Landgraf, M.

    2004-09-01

    Consumer attitudes towards foods have changed in the last two decades increasing requirements for freshlike products. Consequently, less extreme treatments or additives are being required. Minimally processed foods have freshlike characteristics and satisfy this new consumer demand. Besides freshness, the minimally processing also provide convenience required by the market. Salad vegetables can be source of pathogen such as Salmonella, Escherichia coli O157:H7, Shigella spp. The minimal processing does not reduce the levels of pathogenic microorganisms to safe levels. Therefore, this study was carried out in order to improve the microbiological safety and the shelf-life of minimally processed vegetables using gamma radiation. Minimally processed watercress inoculated with a cocktail of Salmonella spp was exposed to 0.0, 0.2, 0.5, 0.7, 1.0, 1.2 and 1.5 kGy. Irradiated samples were diluted 1:10 in saline peptone water and plated onto tryptic soy agar that were incubated at 37°C/24 h. D 10 values for Salmonella spp. inoculated in watercress varied from 0.29 to 0.43 kGy. Therefore, a dose of 1.7 kGy will reduce Salmonella population in watercress by 4 log 10. The shelf-life was increased by 1 {1}/{2} day when the product was exposed to 1 kGy.

  3. Radiation fluid stars in the non-minimally coupled Y(R)F{sup 2} gravity

    Energy Technology Data Exchange (ETDEWEB)

    Sert, Oezcan [Pamukkale University, Department of Mathematics, Faculty of Arts and Sciences, Denizli (Turkey)

    2017-02-15

    We propose a non-minimally coupled gravity model in Y(R)F{sup 2} form to describe the radiation fluid stars which have the radiative equation of state between the energy density ρ and the pressure p given by ρ = 3p. Here F{sup 2} is the Maxwell invariant and Y(R) is a function of the Ricci scalar R. We give the gravitational and electromagnetic field equations in differential form notation taking the infinitesimal variations of the model. We look for electrically charged star solutions to the field equations under the constraint eliminating complexity of the higher order terms in the field equations. We determine the non-minimally coupled function Y(R) and the corresponding model which admits new exact solutions in the interior of the star and the Reissner-Nordstrom solution at the exterior region. Using the vanishing pressure condition at the boundary together with the continuity conditions of the metric functions and the electric charge, we find the mass-radius ratio, charge-radius ratio, and the gravitational surface redshift depending on the parameter of the model for the radiation fluid star. We derive general restrictions for the ratios and redshift of the charged compact stars. We obtain a slightly smaller upper mass-radius ratio limit than the Buchdahl bound 4/9 and a smaller upper redshift limit than the bound of the standard general relativistic stars. (orig.)

  4. A Large Periureteral Lipoma Associated with Renal Lithiasis and Hydronephrosis.

    OpenAIRE

    Hayashi, Tomayoshi; Imamura, Atushi; Tsuda, Nobuo; Shimada, Osamu; Matsunaga, Naofumi; Saito, Yutaka

    1991-01-01

    A rare case of large periureteral lipoma in a 66-year-old woman is reported. The tumor measuring 16×7×7cm in size was located from the upper portion of the right ureter to the renal pelvis. It is considered that the severe hydronephrosis and renal lithiasis occurred as a result of stenosis in the upper urinary tract due to compression by the tumor. Although the differential diagnosis was difficult radiologically, the tumor was easily diagnosed as lipoma by hi stop athological investigation.

  5. Laser radiation in tennis elbow treatment: a new minimally invasive alternative

    Science.gov (United States)

    Paganini, Stefan; Thal, Dietmar R.; Werkmann, Klaus

    1998-01-01

    The epicondylitis humeri radialis (EHR) (tennis elbow), is a common disease in elbow joint pain syndromes. We treated patients with chronic pain for at least one year and no improvement with conservative or operative therapies with a new minimal invasive method, the EHR-Laser radiation (EHR- LR). With this method periepicondylar coagulations were applied to the trigger points of the patients. For this the previously established technique of facet joint coagulation with the Nd:Yag-laser was modified. In a follow-up study of between 6 weeks and 2 years all patients reported either a significant pain reduction or were symptom free. EHR-LR is a new method situated between conservative and surgical treatments for minimal invasive therapy of EHR. Several therapeutic rationales were discussed for the resulting pain reduction.

  6. Ten scenarios from early radiation to late time acceleration with a minimally coupled dark energy

    CERN Document Server

    Fay, Stephane

    2015-01-01

    We consider General Relativity with matter, radiation and a minimally coupled dark energy defined by an equation of state w. Using dynamical system method, we find the equilibrium points of such a theory assuming an expanding Universe and a positive dark energy density. Two of these points correspond to classical radiation and matter dominated epochs for the Universe. For the other points, dark energy mimics matter, radiation or accelerates Universe expansion. We then look for possible sequences of epochs describing a Universe starting with some radiation dominated epoch(s) (mimicked or not by dark energy), then matter dominated epoch(s) (mimicked or not by dark energy) and ending with an accelerated expansion. We find ten sequences able to follow this Universe history without singular behaviour of w at some saddle points. Most of them are new in dark energy literature. To get more than these ten sequences, w has to be singular at some specific saddle equilibrium points. This is an unusual mathematical proper...

  7. Simultaneous laparoscopic management of ureteropelvic junction obstruction and renal lithiasis: the combined experience of two academic centers and review of the literature

    Directory of Open Access Journals (Sweden)

    Stravodimos KG

    2014-05-01

    Full Text Available Konstantinos G Stravodimos,1 Stilianos Giannakopoulos,2 Stavros I Tyritzis,1 Aristeides Alevizopoulos,1 Stefanos Papadoukakis,1 Stavros Touloupidis,2 Constantinos A Constantinides11Department of Urology, Athens University Medical School, Laiko Hospital, Athens, 2Department of Urology, Democritus University of Thrace, Alexandroupolis, GreeceIntroduction: Approximately one out of five patients with ureteropelvic junction obstruction (UPJO present lithiasis in the same setting. We present our outcomes of simultaneous laparoscopic management of UPJO and pelvic or calyceal lithiasis and review the current literature.Methods: Thirteen patients, with a mean age of 42.8±13.3 years were diagnosed with UPJO and pelvic or calyceal lithiasis. All patients were subjected to laparoscopic dismembered Hynes–Anderson pyeloplasty along with removal of single or multiple stones, using a combination of laparoscopic graspers, irrigation, and flexible nephroscopy with nitinol baskets.Results: The mean operative time was 218.8±66 minutes. In two cases, transposition of the ureter due to crossing vessels was performed. The mean diameter of the largest stone was 0.87±0.25 cm and the mean number of stones retrieved was 8.2 (1–32. Eleven out of 13 patients (84.6% were rendered stone-free. Complications included prolonged urine output from the drain in one case (Clavien grade I and urinoma formation requiring drainage in another case (Clavien grade IIIa. The mean postoperative follow-up was 30.2 (7–51 months. No patient has experienced stone or UPJO recurrence.Conclusion: Laparoscopy for the management of UPJO along with renal stone removal seems a very appealing treatment, with all the advantages of minimally invasive surgery. Concomitant renal stones do not affect the outcome of laparoscopic pyeloplasty, at least in the midterm. According to our results and the latest literature data, we advocate laparoscopic management as the treatment of choice for these cases

  8. Urinary lithiasis and urinary tract malformations in children: A retrospective study of 34 cases

    Directory of Open Access Journals (Sweden)

    Jamila Chahed

    2011-01-01

    Full Text Available Background: Although the association of urinary lithiasis and urinary tract malformation is not rare, their management poses challenges. The aim of this study was to evaluate the relationship between urolithiasis and malformations of the urinary system. There were 34 patients (19 males and 15 females with a mean age of 4.8 years (range, 2 months to 14 years. All patients had urinary lithiasis with a urinary tract malformation. Abdominal pain was the most frequent clinical symptom (38%. Urinary infection was found in 7 patients (21% and macroscopic haematuria was present in 10 patients (29%. The most frequent urinary tract malformations were megaureter (8 cases, uretero-pelvic junction obstruction (7 cases and vesico-ureteric reflux (8 cases, but its malformative origin could not be confirmed. Treatment consisted of lithiasis extraction in 32 cases associated with specific treatment of the uropathy in 27 cases. Postoperative outcome was uneventful in all cases. In fact, urinary lithiasis and urinary tract malformation association is not rare. Indeed, 9-34% of urinary lithiasis are noted to be associated with urinary tract malformation. Positive diagnosis relies specifically on kidney ultrasound, intravenous urography, and urethrocystography. Treatment depends on the type of urinary tract malformation, localisation and size of the urinary lithiasis. Conclusion: In conclusion, urinary lithiasis and urinary tract malformation association is a frequent eventuality. Surgical intervention is the usual mode of treatment.

  9. Static jaw collimation settings to minimize radiation dose to normal brain tissue during stereotactic radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Han, Eun Young, E-mail: eyhan@uams.edu [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR (United States); Zhang Xin; Yan Yulong; Sharma, Sunil; Penagaricano, Jose [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR (United States); Moros, Eduardo [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL (United States); Corry, Peter [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR (United States)

    2012-01-01

    At University of Arkansas for Medical Sciences (UAMS) intracranial stereotactic radiosurgery (SRS) is performed by using a linear accelerator with an add-on micromultileaf collimator (mMLC). In our clinical setting, static jaws are automatically adapted to the furthest edge of the mMLC-defined segments with 2-mm (X jaw) and 5-mm (Y jaw) margin and the same jaw values are applied for all beam angles in the treatment planning system. This additional field gap between the static jaws and the mMLC allows additional radiation dose to normal brain tissue. Because a radiosurgery procedure consists of a single high dose to the planning target volume (PTV), reduction of unnecessary dose to normal brain tissue near the PTV is important, particularly for pediatric patients whose brains are still developing or when a critical organ, such as the optic chiasm, is near the PTV. The purpose of this study was to minimize dose to normal brain tissue by allowing minimal static jaw margin around the mMLC-defined fields and different static jaw values for each beam angle or arc. Dose output factors were measured with various static jaw margins and the results were compared with calculated doses in the treatment planning system. Ten patient plans were randomly selected and recalculated with zero static jaw margins without changing other parameters. Changes of PTV coverage, mean dose to predefined normal brain tissue volume adjacent to PTV, and monitor units were compared. It was found that the dose output percentage difference varied from 4.9-1.3% for the maximum static jaw opening vs. static jaw with zero margins. The mean dose to normal brain tissue at risk adjacent to the PTV was reduced by an average of 1.9%, with negligible PTV coverage loss. This dose reduction strategy may be meaningful in terms of late effects of radiation, particularly in pediatric patients. This study generated clinical knowledge and tools to consistently minimize dose to normal brain tissue.

  10. [Strategy changes in the treatment of ureteral lithiasis and nephritic colic].

    Science.gov (United States)

    González Enguita, C; Calahorra Fernández, F J; García de la Peña, E; Rodríguez-Miñón Cifuentes, J L; Vela Navarrete, R

    1996-04-01

    Since lithotripters were first introduced to the clinical practice in 1980, extracorporeal shock wave lithotrite (ESWL) has been universally recognized as the first choice to resolve urinary tract lithiasis, ureteral calculi being the most susceptible lithiasic site for controversy. The urologist approach to the lithiasic patient has changed mainly as compared to that of ureteral calculi. These profound changes translate an undeniable advance of the extracorporeal procedures versus those of endourology, basically based on ESWL low morbidity. In those cases when lithiasis is found in a situation of nephritic colic, there is a real therapeutical chance with ESWL, thus leading to drug therapy losing its major role. We present 768 patients with ureteral lithiasis (1991-1994), 20-25% of which were examined for a nephritic colic. Once the colic situation is overcome in all instances, 35% will require a new lithotrite for complete lithiasic resolution. Overall, our rate of successful ureteral lithiasis resolution is 97% (30% need repeated session).

  11. Digital nuclear radiation spectroscopy: Hardware requirements to minimize energy resolution degradation

    Energy Technology Data Exchange (ETDEWEB)

    Riva, M., E-mail: Marco.Riva@enea.it; Esposito, B.; Marocco, D.; Belli, F.

    2015-10-15

    Highlights: • Systematic requirement analysis of the digitizing process. • Synthetic pulses with different Full Width Half Maximum (FWHM). • Statistical and systematic error study. • Effects of the pulse amplitude reduction respect to the full scale on the error. • Hardware architecture considerations. - Abstract: Nuclear radiation spectroscopy is now often relying on digital acquisition techniques. The present paper addresses the problem of analyzing the requirements of the digitizer in terms of sampling frequency and number of bits to minimize the energy resolution degradation caused by the digitizing process. The analysis is performed using synthetic pulses (with different amplitude and Full Width Half Maximum) of typical nuclear spectroscopy detectors and the pulse area as energy estimate. Additional relevant issues, such as the hardware architecture and the data throughput speed, are also discussed.

  12. Reliability of pre- and intraoperative tests for biliary lithiasis

    Energy Technology Data Exchange (ETDEWEB)

    Escallon, A. Jr.; Rosales, W.; Aldrete, J.S.

    1985-05-01

    The records of 242 patients, operated consecutively for biliary lithiasis, were analyzed to determine the reliability of oral cholecystography (OCG), ultrasonography (US), and HIDA in detecting biliary calculi. Preoperative interpretations were correlated to operative findings. OCG obtained in 138 patients was accurate in 92%. US obtained in 150 was correct in 89%. The accuracy of HIDA was 92% in acute and 78% in chronic cholecystitis. Intraoperative cholangiography (IOC) done in 173 patients indicated the need for exploratory choledochotomy in 24; 21 had choledocholithiasis. These observations suggest that OCG and US are very accurate, but not infallible, in detecting cholelithiasis. US should be done first; when doubt persists, the addition of OCG allows the preoperative diagnosis of gallstones in 97% of the cases. HIDA is highly accurate but not infallible in detecting acute calculous cholecystitis. IOC is very reliable in detecting choledocholithiasis; thus, its routine is justifiable.

  13. Reliability of pre- and intraoperative tests for biliary lithiasis.

    Science.gov (United States)

    Escallon, A; Rosales, W; Aldrete, J S

    1985-01-01

    The records of 242 patients, operated consecutively for biliary lithiasis, were analyzed to determine the reliability of oral cholecystography (OCG), ultrasonography (US), and HIDA in detecting biliary calculi. Preoperative interpretations were correlated to operative findings. OCG obtained in 138 patients was accurate in 92%. US obtained in 150 was correct in 89%. The accuracy of HIDA was 92% in acute and 78% in chronic cholecystitis. Intraoperative cholangiography (IOC) done in 173 patients indicated the need for exploratory choledochotomy in 24; 21 had choledocholithiasis. These observations suggest that OCG and US are very accurate, but not infallible, in detecting cholelithiasis. US should be done first; when doubt persists, the addition of OCG allows the preoperative diagnosis of gallstones in 97% of the cases. HIDA is highly accurate but not infallible in detecting acute calculous cholecystitis. IOC is very reliable in detecting choledocholithiasis; thus, its routine is justifiable. PMID:3888131

  14. Treatment of urinary lithiasis following kidney transplantation with extracorporeal shock-wave lithotripsy

    Institute of Scientific and Technical Information of China (English)

    LI Sha-dan; WANG Qing-tang; CHEN Wei-guo

    2011-01-01

    Background The incidence of urinary lithiasis following kidney transplantation is very low, and decision-supporting data are not available. The aim of this study was to review the diagnosis and treatment of urinary lithiasis following kidney transplantation, which is of realistic significance to reduce urinary lithiasis following kidney transplantation, prolong the survival of renal allografts.Methods The incidence, diagnosis and treatment of urinary lithiasis in ten patients following kidney transplantation were analyzed retrospectively. Seven out of these patients had stones sized approximately 0.4-1.1 cm, and they were treated with low-voltage, low-frequency extracorporeal shock-wave lithotripsy (ESWL). Two patients had stones sized <0.3 cm and they underwent cystoscopy and ureteroscopy. The ureteral catheter endoscopes were inserted in a retrograde manner to mobilize stones repeatedly. After elimination of obstruction, a ureteral double J stent was indwelt.One patient had a pelvic stone (1.2 cm), which was removed surgically.Results The major clinical manifestations were hematuria, oliguria or anuria. Some patients were asymptomatic and they were diagnosed through laboratory tests and imaging examinations, e.g., ultrasonography. After elimination of obstruction, subjective symptoms disappeared in all patients, and the function of renal allografts recovered. A six-month follow-up indicated no remnant stones or lithiasis relapse.Conclusions The diagnosis and treatment of renal allograft lithiasis are challenging. After prompt and appropriate treatment, the prognosis was satisfactory, and permanent renal functional impairment did not occur in most patients.

  15. Static jaw collimation settings to minimize radiation dose to normal brain tissue during stereotactic radiosurgery.

    Science.gov (United States)

    Han, Eun Young; Zhang, Xin; Yan, Yulong; Sharma, Sunil; Penagaricano, Jose; Moros, Eduardo; Corry, Peter

    2012-01-01

    At the University of Arkansas for Medical Sciences (UAMS) intracranial stereotactic radiosurgery (SRS) is performed by using a linear accelerator with an add-on micromultileaf collimator (mMLC). In our clinical setting, static jaws are automatically adapted to the furthest edge of the mMLC-defined segments with 2-mm (X jaw) and 5-mm (Y jaw) margin and the same jaw values are applied for all beam angles in the treatment planning system. This additional field gap between the static jaws and the mMLC allows additional radiation dose to normal brain tissue. Because a radiosurgery procedure consists of a single high dose to the planning target volume (PTV), reduction of unnecessary dose to normal brain tissue near the PTV is important, particularly for pediatric patients whose brains are still developing or when a critical organ, such as the optic chiasm, is near the PTV. The purpose of this study was to minimize dose to normal brain tissue by allowing minimal static jaw margin around the mMLC-defined fields and different static jaw values for each beam angle or arc. Dose output factors were measured with various static jaw margins and the results were compared with calculated doses in the treatment planning system. Ten patient plans were randomly selected and recalculated with zero static jaw margins without changing other parameters. Changes of PTV coverage, mean dose to predefined normal brain tissue volume adjacent to PTV, and monitor units were compared. It was found that the dose output percentage difference varied from 4.9-1.3% for the maximum static jaw opening vs. static jaw with zero margins. The mean dose to normal brain tissue at risk adjacent to the PTV was reduced by an average of 1.9%, with negligible PTV coverage loss. This dose reduction strategy may be meaningful in terms of late effects of radiation, particularly in pediatric patients. This study generated clinical knowledge and tools to consistently minimize dose to normal brain tissue.

  16. Minimal Internal Radiation Exposure in Residents Living South of the Fukushima Daiichi Nuclear Power Plant Disaster.

    Science.gov (United States)

    Akiyama, Junichi; Kato, Shigeaki; Tsubokura, Masaharu; Mori, Jinichi; Tanimoto, Tetsuya; Abe, Koichiro; Sakai, Shuji; Hayano, Ryugo; Tokiwa, Michio; Shimmura, Hiroaki

    2015-01-01

    Following the Fukushima nuclear power plant disaster, assessment of internal radiation exposure was indispensable to predict radiation-related health threats to residents of neighboring areas. Although many evaluations of internal radiation in residents living north and west of the crippled Fukushima nuclear power plant are available, there is little information on residents living in areas south of the plant, which were similarly affected by radio-contamination from the disaster. To assess the internal radio-contamination in residents living in affected areas to the south of the plant or who were evacuated into Iwaki city, a whole body counter (WBC) screening program of internal radio-contamination was performed on visitors to the Jyoban hospital in Iwaki city, which experienced less contamination than southern areas adjacent to the nuclear plant. The study included 9,206 volunteer subjects, of whom 6,446 were schoolchildren aged 4-15 years. Measurements began one year after the incident and were carried out over the course of two years. Early in the screening period only two schoolchildren showed Cs-137 levels that were over the detection limit (250 Bq/body), although their Cs-134 levels were below the detection limit (220 Bq/body). Among the 2,760 adults tested, 35 (1.3%) had detectable internal radio-contamination, but only for Cs-137 (range: 250 Bq/body to 859 Bq/body), and not Cs-134. Of these 35 subjects, nearly all (34/35) showed elevated Cs-137 levels only during the first year of the screening. With the exception of potassium 40, no other radionuclides were detected during the screening period. The maximum annual effective dose calculated from the detected Cs-137 levels was 0.029 and 0.028 mSv/year for the schoolchildren and adults, respectively, which is far below the 1 mSv/year limit set by the government of Japan. Although the data for radiation exposure during the most critical first year after the incident are unavailable due to a lack of systemic

  17. Minimal Internal Radiation Exposure in Residents Living South of the Fukushima Daiichi Nuclear Power Plant Disaster.

    Directory of Open Access Journals (Sweden)

    Junichi Akiyama

    Full Text Available Following the Fukushima nuclear power plant disaster, assessment of internal radiation exposure was indispensable to predict radiation-related health threats to residents of neighboring areas. Although many evaluations of internal radiation in residents living north and west of the crippled Fukushima nuclear power plant are available, there is little information on residents living in areas south of the plant, which were similarly affected by radio-contamination from the disaster. To assess the internal radio-contamination in residents living in affected areas to the south of the plant or who were evacuated into Iwaki city, a whole body counter (WBC screening program of internal radio-contamination was performed on visitors to the Jyoban hospital in Iwaki city, which experienced less contamination than southern areas adjacent to the nuclear plant. The study included 9,206 volunteer subjects, of whom 6,446 were schoolchildren aged 4-15 years. Measurements began one year after the incident and were carried out over the course of two years. Early in the screening period only two schoolchildren showed Cs-137 levels that were over the detection limit (250 Bq/body, although their Cs-134 levels were below the detection limit (220 Bq/body. Among the 2,760 adults tested, 35 (1.3% had detectable internal radio-contamination, but only for Cs-137 (range: 250 Bq/body to 859 Bq/body, and not Cs-134. Of these 35 subjects, nearly all (34/35 showed elevated Cs-137 levels only during the first year of the screening. With the exception of potassium 40, no other radionuclides were detected during the screening period. The maximum annual effective dose calculated from the detected Cs-137 levels was 0.029 and 0.028 mSv/year for the schoolchildren and adults, respectively, which is far below the 1 mSv/year limit set by the government of Japan. Although the data for radiation exposure during the most critical first year after the incident are unavailable due to a lack

  18. The prevalence of urinary lithiasis in children in Van Region, Turkey.

    Science.gov (United States)

    Akgün, Cihangir; Kayan, Mustafa; Tuncer, Oğuz; Arslan, Sükrü; Caksen, Hüseyin; Ataş, Bülent; Akbayram, Sinan

    2009-09-01

    We aimed to determine the prevalence and etiology of urinary lithiasis in childhood in our region, Van, Turkey. A total of 1120 children were included in the study. Urinary ultrasonography was performed in all the children between April 2003 and June 2003. During the study, the kidneys were examined longitudinally and transversally using a 3.75 MHz convex probe in a Hitachi EUB -315 ultrasonography machine. The children's ages ranged from 7 years to 14 years (10.16 +/- 1.92 years) and 572 (51.1%) were males and 548 (48.9%) females. Urinary ultrasonography showed that 19 (1.7%) children had urinary lithiasis, which was in the right kidney in 15 children and in the left kidney in four children. Urinary lithiasis was in the upper urinary tract in all children. The etiological studies showed metabolic disorder in 14 children, and congenital renal anomaly in one child, but no underlying cause was diagnosed in four children. In conclusion, we found that was the prevalence of urinary lithiasis was 1.7% in school-aged children in our region. It was also noted that all urinary lithiasis was in the upper urinary system and its most common cause was metabolic disorder.

  19. Effects of polyphenols from grape seeds on renal lithiasis.

    Science.gov (United States)

    Grases, Felix; Prieto, Rafel M; Fernandez-Cabot, Rafel A; Costa-Bauzá, Antonia; Tur, Fernando; Torres, Jose Juan

    2015-01-01

    Nephrolithiasis is a complex disease that results from a combination of factors related to both urine composition and kidney morphoanatomy. Development of calcium oxalate monohydrate papillary calculi is linked to initial subepithelial calcification of renal papilla. Progressive tissue calcification depends on preexisting injury and involves reactive oxygen species. Many plant extracts that protect against oxidative stress manifest antilithiasic activity. Our study focused on determining the effects of polyphenols on a lithiasis rat model. Rats were pretreated with polyphenols and grape seed extracts, followed by posterior induction of hyperoxalosis via treatment with ethylene glycol plus NH4Cl. The concentrations of calcium and other elements in kidney were determined, along with histological examination of kidney and 24 h urine analysis. Significant differences were observed in the renal calcium content between the control plus ethylene glycol-treated group and the epicatechin plus ethylene glycol-treated, red grape seed extract plus ethylene glycol-treated, and white grape seed extract plus ethylene glycol-treated groups, with reductions of about 50%. The antioxidant activity of polyphenols extracted from red and white grape seeds may be critical in the prevention of calcium oxalate monohydrate papillary calculus formation, particularly if calculi are induced by lesions caused by cytotoxic compounds with oxidative capacity.

  20. Effects of Polyphenols from Grape Seeds on Renal Lithiasis

    Directory of Open Access Journals (Sweden)

    Felix Grases

    2015-01-01

    Full Text Available Nephrolithiasis is a complex disease that results from a combination of factors related to both urine composition and kidney morphoanatomy. Development of calcium oxalate monohydrate papillary calculi is linked to initial subepithelial calcification of renal papilla. Progressive tissue calcification depends on preexisting injury and involves reactive oxygen species. Many plant extracts that protect against oxidative stress manifest antilithiasic activity. Our study focused on determining the effects of polyphenols on a lithiasis rat model. Rats were pretreated with polyphenols and grape seed extracts, followed by posterior induction of hyperoxalosis via treatment with ethylene glycol plus NH4Cl. The concentrations of calcium and other elements in kidney were determined, along with histological examination of kidney and 24 h urine analysis. Significant differences were observed in the renal calcium content between the control plus ethylene glycol-treated group and the epicatechin plus ethylene glycol-treated, red grape seed extract plus ethylene glycol-treated, and white grape seed extract plus ethylene glycol-treated groups, with reductions of about 50%. The antioxidant activity of polyphenols extracted from red and white grape seeds may be critical in the prevention of calcium oxalate monohydrate papillary calculus formation, particularly if calculi are induced by lesions caused by cytotoxic compounds with oxidative capacity.

  1. Predictors of common bile duct lithiasis in laparoscopic era

    Institute of Scientific and Technical Information of China (English)

    George Sgourakis; Georgia Dedemadi; Athanasios Stamatelopoulos; Emmanuel Leandros; Dionysius Voros; Konstantinos Karaliotas

    2005-01-01

    AIM: To analyze retrospectively the records of 294 conse-cutive patients operated upon for gallbladder stones, to determine the predictive factors of synchronous common bile duct (CBD) stones and validate prospectively the generated model. METHODS: The prognostic estimation of a biochemical test and ultrasonography alone to differentiate between the absence and presence of choledocholithiasis was assessed using receiver operating characteristics curve analysis. Multivariate analysis was employed using discriminant analysis for establishment of a best model. Prospective validation of the model was made.RESULTS: Discriminant forward stepwise analysis disclosed that high values (≥ 2×normal) of SGOT, ALP, conjugated bilirubin and CBD diameter on ultrasound ≥ 10 mm were all prognostic factors of CBD lithiasis in univariate and multivariate analysis, P<0.01. History was not included in the model. Prospective validation of the model was performed by multivariate analysis using Visual General Stepwise Regression. Positive predictive value,when considering all these predictors, was 93.3%, while the negative predictive value was 88.8%. Sensitivity of the model was 96.5% and specificity 80%.CONCLUSION: The above model can be objectively applied to predict the presence of CBD stones.

  2. Perforated Meckel’s Diverticulum Lithiasis: An Unusual Cause of Peritonitis

    Directory of Open Access Journals (Sweden)

    Umasankar Mathuram Thiyagarajan

    2013-01-01

    Full Text Available Meckel’s diverticulum is the commonest congenital malformation of gastrointestinal tract and represents a persistent remnant of the omphalomesenteric duct. Although it mostly remains silent, it can present as bleeding, perforation, intestinal obstruction, intussusception, and tumours. These complications, especially bleeding, tend to be more common in the paediatric group and intestinal obstruction in adults. Stone formation (lithiasis in Meckel’s diverticulum is rare. We report a case of Meckel’s diverticulum lithiasis which presented as an acute abdomen in an otherwise healthy individual. The patient underwent an exploratory laparotomy which revealed a perforated Meckel’s diverticulum with lithiasis; a segmental resection with end-to-end anastomosis of small bowel was performed. Patient recovery was delayed due to pneumonia, discharged on day 20 with no further complications at 6 months following surgery.

  3. Acute renal failure due to bilateral uric acid lithiasis in infants.

    Science.gov (United States)

    Kaya, Mete; Boleken, M Emin; Soran, Mustafa; Kanmaz, Turan; Yücesan, Selçuk

    2007-06-01

    Acute renal failure (ARF) is one of the complications of urolithiasis, but the role of medical treatment to relieve urinary obstruction in children with ARF is uncertain. We report on infants with acute obstructive uric acid lithiasis. We describe presentation features as well as diagnosis methods and medical treatment in five infants who were admitted to our institution with ARF due to uric acid lithiasis. The medical treatments for all patients were fluid liberalization, urine alkalinization, and oral allopurinol. Two children underwent urinary diversion. Within 8 h, urine output improved in all patients, and the stones passed spontaneously. All obstructed kidneys were relieved with medical treatment, and no renal sequel remained. So this series has showed a role of medical therapy in acute obstructive uric acid lithiasis.

  4. [Frequency and clinical course of biliary lithiasis in patients with severe preeclampsia].

    Science.gov (United States)

    Vázquez-Rodríguez, Juan Gustavo; Pérez-Rodrĭguez, Maritza Janet

    2010-11-01

    Biliary lithiasis in patients with severe preeclampsia has not been well studied. To describe the frequency and clinical course of biliary lithiasis in patients with severe preeclampsia. Cross-sectional study on 141 women with severe preeclampsia who had an abdominal ultrasound performed during the pre-partum period or in the immediate puerperium. Patients were treated in the Intensive Care Unit of the Hospital de Ginecologia y Obstetricia núm. 3, Centro Medico Nacional La Raza, IMSS (Mexico), in the period of November 26, 2006 to June 26, 2009. Findings from gallbladder lithiasis (sand, solitary stone, multiple stones or wall calcification) and choledocho conduit were reported. Significant maternal data (clinical and laboratory) and perinatal results of patients without stones (group A) were compared to patients (group B) with stones. Measures of central tendency and dispersion, and T-test were used. Frequency of gallbladder lithiasis was 15% (21 cases). Solitary stone were found in 12 cases, multiple stones in seven cases and gallbladder calcification in two cases. There were no cases of choledocholithiasis. Epigastric pain was present in 13 cases (9.2%: group A, 10 cases [7.1%] vs. group B, 3 cases [2.1%], p = 0.06). There were no complications in patients with lithiasis and none required invasive procedures. Clinical evolution and perinatal results were similar in both groups. Duration of stay in the intensive care unit was similar (group A, 2.2 +/- 0.18 days vs. group B, 2.1 +/- 0.13 days, p = 0.86). The frequency of biliary lithiasis in patients with severe preeclampsia was 15%. There were no adverse effects on the maternal clinical course or on the perinatal results.

  5. [Renal lithiasis. Biochemical changes in the follow-up].

    Science.gov (United States)

    Spivacow, Francisco R; del Valle, Elisa E; Zancheta, José R

    2006-01-01

    With the aim of assessing if biochemical changes occur in the follow up of patients with renal lithiasis, 237 patients were studied (115 women and 122 men, mean age 39 +/- 8 and 42 +/- 7 years, respectively) and controlled during 27.3 +/- 19.3 months. All of them had previously undergone metabolic evaluations at baseline and one or more than one control studies afterwards. Patients with a diagnosis of sponge kidney, renal tubular acidosis, primary hyperparathyroidism, anatomical malformations of the urinary tract, or urinary infections were not included. Two populations were identified: those who presented changes in the baseline diagnosis (139 patients, Group I) and those who presented no changes (98 patients, Group II). In these groups, no differences were observed in baseline metabolic diagnoses or in the follow-up period. Hypocitraturia was the additional diagnosis most frequently observed (43.1%), followed by Idiopatic hypercalciuria (20.8%) and abnormalities of uric acid (16.5%). In the group of 110 patients followed up for more than 3 years, 37 patients recurred (33%). Among the latter, 25 (23%) changed the baseline metabolic diagnosis vs. 12 (11%) that maintained the same diagnosis (p < 0.002). Changes in metabolic disorders were frequently observed in the follow up of patients with nephrolithiasis. These changes are not necessarily associated with the diet indicated or drug treatment. Hypocitraturia was the additional metabolic disorder most frequently found. In general, there is a higher recurrence rate in those patients who present changes in their biochemical parameters and undergo no treatment.

  6. Addition of Bevacizumab to Standard Radiation Therapy and Daily Temozolomide Is Associated With Minimal Toxicity in Newly Diagnosed Glioblastoma Multiforme

    Energy Technology Data Exchange (ETDEWEB)

    Vredenburgh, James J., E-mail: vrede001@mc.duke.edu [Department of Medicine, Duke University Medical Center, Durham, NC (United States); Desjardins, Annick [Department of Neurology, Duke University Medical Center, Durham, NC (United States); Kirkpatrick, John P. [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); Reardon, David A. [Department of Surgery, Duke University Medical Center, Durham, NC (United States); Department of Pediatrics, Duke University Medical Center, Durham, NC (United States); Peters, Katherine B. [Department of Neurology, Duke University Medical Center, Durham, NC (United States); Herndon, James E.; Marcello, Jennifer [Department of Cancer Center Biostatistics, Duke University Medical Center, Durham, NC (United States); Bailey, Leighann; Threatt, Stevie; Sampson, John; Friedman, Allan [Department of Surgery, Duke University Medical Center, Durham, NC (United States); Friedman, Henry S. [Department of Surgery, Duke University Medical Center, Durham, NC (United States); Department of Pediatrics, Duke University Medical Center, Durham, NC (United States)

    2012-01-01

    Purpose: To determine the safety of the addition of bevacizumab to standard radiation therapy and daily temozolomide for newly diagnosed glioblastoma multiforme (GBM). Methods and Materials: A total of 125 patients with newly diagnosed GBM were enrolled in the study, and received standard radiation therapy and daily temozolomide. All patients underwent a craniotomy and were at least 2 weeks postoperative. Radiation therapy was administered in 1.8-Gy fractions, with the clinical target volume for the primary course treated to a dose of 45 to 50.4 Gy, followed by a boost of 9 to 14.4 Gy, to a total dose of 59.4 Gy. Patients received temozolomide at 75 mg/m{sup 2} daily throughout the course of radiation therapy. Bevacizumab was given at 10 mg/kg intravenously every 14 days, beginning a minimum of 4 weeks postoperatively. Results: Of the 125 patients, 120 (96%) completed the protocol-specified radiation therapy. Five patients had to stop the protocol therapy, 2 patients with pulmonary emboli, and 1 patient each with a Grade 2 central nervous system hemorrhage, Grade 4 pancytopenia, and wound dehiscence requiring surgical intervention. All 5 patients ultimately finished the radiation therapy. After radiation therapy, 3 patients had progressive disease, 2 had severe fatigue and decreased performance status, 1 patient had a colonic perforation, and 1 had a rectal fissure; these 7 patients therefore did not proceed with the protocol-specified adjuvant temozolomide, bevacizumab, and irinotecan. However, 113 patients (90%) were able to continue on study. Conclusions: The addition of bevacizumab to standard radiation therapy and daily temozolomide was found to be associated with minimal toxicity in patients newly diagnosed with GBM.

  7. RADIATION HYGIENIC CONSEQUENCES OF THE ACCIDENT AT THE CHERNOBYL NPP AND THE TASKS OF THEIR MINIMIZATION

    Directory of Open Access Journals (Sweden)

    G. G. Onischenko

    2009-01-01

    Full Text Available The paper presents data on the role and results of activities of Rospotrebnadzor bodies and institutions in the field of ensuring population radiation protection during various periods since accident at the Chernobyl NPP. Radiation hygienic characterization of territories affected by radioactive contamination from the accident, population exposure dose range, issues of ensuring radiological well-being of population and ways of their solution are being presented in the paper.

  8. Implementation of Radiation, Ablation, and Free Energy Minimization Modules for Coupled Simulations of Hypersonic Flow

    Science.gov (United States)

    Gnoffo, Peter A.; Johnston, Christopher O.; Thompson, Richard A.

    2009-01-01

    A description of models and boundary conditions required for coupling radiation and ablation physics to a hypersonic flow simulation is provided. Chemical equilibrium routines for varying elemental mass fraction are required in the flow solver to integrate with the equilibrium chemistry assumption employed in the ablation models. The capability also enables an equilibrium catalytic wall boundary condition in the non-ablating case. The paper focuses on numerical implementation issues using FIRE II, Mars return, and Apollo 4 applications to provide context for discussion. Variable relaxation factors applied to the Jacobian elements of partial equilibrium relations required for convergence are defined. Challenges of strong radiation coupling in a shock capturing algorithm are addressed. Results are presented to show how the current suite of models responds to a wide variety of conditions involving coupled radiation and ablation.

  9. Minimizing radiation dose to patient and staff during fluoroscopic, nasoenteral tube insertions

    Energy Technology Data Exchange (ETDEWEB)

    Rudin, S.; Bednarek, D.R. (New York Univ., NY (United States). School of Medicine)

    1992-02-01

    Since the fluoroscopic image during nasoenteral tube placements is used for guidance and not for diagnosis, a lower contrast image with increased quantum mottle can be easily tolerated. The three methods to reduce the radiation dose rate investigated consisted of removing camera from the image intensifier output phosphor, and setting the fluoroscopic mA to the minimum value so that the kVp could be maximized. Fluoroscopic frozen video frames of a clinical tube insertion comparing the images with and without the dose-saving techniques are presented. Measurements of the radiation dose rates using a Plexiglas phantom show that the dose for patient and staff during fluoroscopic-guided nasoenteral tube placements can be reduced by over a factor of 10 without significantly adversely affecting the actual placement procedure. (author).

  10. Minimizing the acoustic power radiated by a fluid-loaded curved panel excited by turbulent boundary layer flow.

    Science.gov (United States)

    Shepherd, Micah R; Hambric, Stephen A

    2014-11-01

    In order to address noise control problems in the design stage, structural-acoustic optimization procedures can be used to find the optimal design for reduced noise or vibration. However, most structural-acoustic optimization procedures are not general enough to include both heavy fluid loading and complex forcing functions. Additionally, it can be difficult to determine and assess trade-offs between weight and sound radiation. A structural-acoustic optimization approach is presented for minimizing the radiated power of structures with heavy fluid loading excited by complex forcing functions. The procedure is demonstrated on a curved underwater panel excited by a point drive and by turbulent boundary layer flow. To facilitate more efficient analysis, an uncorrelated pressure assumption is made for the turbulent boundary layer forcing function. The thicknesses of groups of elements were used as the design variables with an adaptive covariance matrix evolutionary strategy as the search algorithm. The objective function was a weighted sum of total sound power and panel mass and the Pareto front was computed to show the optimum trade-off between the two objectives. The optimal designs are presented which illustrate the best methods for reducing radiated sound and mass simultaneously.

  11. [Primary intestinal-type adenocarcinoma of the renal pelvis associated with lithiasis: a case report].

    Science.gov (United States)

    Renaud, Florence; Berthon, Nicolas; Lemaitre, Laurent; Castillo, Christine; Copin, Marie-Christine; Aubert, Sébastien; Leroy, Xavier

    2010-10-01

    A case of primary adenocarcinoma of the renal pelvis occurring in a 57-year-old woman who had no previous history is reported. The lesions were thought to be a renal destruction by pyelolithiasis upon symptomatology and imaging study data. A nephrectomy was thus performed. Macroscopic examination revealed voluminous and exophytic lesions surrounding lithiasis. Diagnosis of intestinal-type adenocarcinoma of the renal pelvis was established on histological examination. No evidence of other tumor localization was revealed by complete exploration. Primary adenocarcinoma of renal pelvis is a rare and often mucinous intestinal-type tumour. Chronic inflammation and renal lithiasis seem to be associated with this tumour. Few cases are reported and prognosis is doubtful. The main differential diagnosis to eliminate is secondary lesions to the kidney of adenocarcinoma from another origin. A careful pathological examination in case of pyelonephritic kidney is necessary to look for an associated tumour.

  12. Minimizing the ILL-conditioning in the analysis by gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Halisson Alberdan C.; Melo, Silvio de Barros; Dantas, Carlos; Lima, Emerson Alexandre; Silva, Ricardo Martins; Moreira, Icaro Valgueiro M., E-mail: hacc@cin.ufpe.br, E-mail: sbm@cin.ufpe.br, E-mail: rmas@cin.ufpe.br, E-mail: ivmm@cin.ufpe.br, E-mail: ccd@ufpe.br, E-mail: eal@cin.ufpe.br [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil); Meric, Ilker, E-mail: lker.Meric@ift.uib.no [University Of Bergen (Norway)

    2015-07-01

    A non-invasive method which can be employed for elemental analysis is the Prompt-Gamma Neutron Activation Analysis. The aim is to estimate the mass fractions of the different constituent elements present in the unknown sample basing its estimations on the energies of all the photopeaks in their spectra. Two difficulties arise in this approach: the constituents are unknown, and the composed spectrum of the unknown sample is a nonlinear combination of the spectra of its constituents (which are called libraries). An iterative method that has become popular is the Monte Carlo Library Least Squares. One limitation with this method is that the amount of noise present in the spectra is not negligible, and the magnitude differences in the photon counting produce a bad conditioning in the covariance matrix employed by the least squares method, affecting the numerical stability of the method. A method for minimizing the numerical instability provoked by noisy spectra is proposed. Corresponding parts of different spectra are selected as to minimize the condition number of the resulting covariance matrix. This idea is supported by the assumption that the unknown spectrum is a linear combination of its constituent's spectra, and the fact that the amount of constituents is so small (typically ve of them). The selection of spectrum parts is done through Greedy Randomized Adaptive Search Procedures, where the cost function is the condition number that derives from the covariance matrix produced out of the selected parts. A QR factorization is also applied to the nal covariance matrix to reduce further its condition number, and transferring part of its bad conditioning to the basis conversion matrix. (author)

  13. Surgeons' exposure to radiation in single- and multi-level minimally invasive transforaminal lumbar interbody fusion; a prospective study.

    Directory of Open Access Journals (Sweden)

    Haruki Funao

    Full Text Available Although minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF has widely been developed in patients with lumbar diseases, surgeons risk exposure to fluoroscopic radiation. However, to date, there is no studies quantifying the effective dose during MIS-TLIF procedure, and the radiation dose distribution is still unclear. In this study, the surgeons' radiation doses at 5 places on the bodies were measured and the effective doses were assessed during 31 consecutive 1- to 3-level MIS-TLIF surgeries. The operating surgeon, assisting surgeon, and radiological technologist wore thermoluminescent dosimeter on the unshielded thyroid, chest, genitals, right middle finger, and on the chest beneath a lead apron. The doses at the lens and the effective doses were also calculated. Mean fluoroscopy times were 38.7, 53.1, and 58.5 seconds for 1, 2, or 3 fusion levels, respectively. The operating surgeon's mean exposures at the lens, thyroid, chest, genitals, finger, and the chest beneath the shield, respectively, were 0.07, 0.07, 0.09, 0.14, 0.32, and 0.05 mSv in 1-level MIS-TLIF; 0.07, 0.08, 0.09, 0.18, 0.34, and 0.05 mSv in 2-level; 0.08, 0.09, 0.14, 0.15, 0.36, and 0.06 mSv in 3-level; and 0.07, 0.08, 0.10, 0.15, 0.33, and 0.05 mSv in all cases. Mean dose at the operating surgeon's right finger was significantly higher than other measurements parts (P<0.001. The operating surgeon's effective doses (0.06, 0.06, and 0.07 mSv for 1, 2, and 3 fusion levels were low, and didn't differ significantly from those of the assisting surgeon or radiological technologist. Revision MIS-TLIF was not associated with higher surgeons' radiation doses compared to primary MIS-TLIF. There were significantly higher surgeons' radiation doses in over-weight than in normal-weight patients. The surgeons' radiation exposure during MIS-TLIF was within the safe level by the International Commission on Radiological Protection's guidelines. The accumulated radiation exposure

  14. Osteoradionecrosis of the mandible. Minimized risk profile following Intensity-Modulated Radiation Therapy (IMRT)

    Energy Technology Data Exchange (ETDEWEB)

    Studer, G.; Huguenin, P.; Luetolf, U.M.; Glanzmann, C. [Dept. of Radiation Oncology, Univ. Hospital, Zurich (Switzerland); Studer, S.P.; Zwahlen, R.A.; Graetz, K.W. [Dept. of Craniomaxillofacial Surgery, Univ. Hospital, Zurich (Switzerland)

    2006-05-15

    Background and purpose: osteoradionecrosis (ON) of the mandible is a serious late complication of high-dose radiation therapy for tumors of the oropharynx and oral cavity. After doses between 60 and 72 Gy using standard fractionation, an incidence of ON between 5% and 15% is reported in a review from 1989, whereas in more recent publications using moderately accelerated or hyperfractionated irradiation and doses between 69 and 81 Gy, the incidence of ON is between < 1% and {proportional_to} 6%. Intensity-modulated radiation therapy (IMRT) is expected to translate into a further important reduction of ON. The aim of this descriptive study was to assess absolute and relative bone volumes exposed to high IMRT doses, related to observed bone tolerance. Patients and methods: between December 2001 and November 2004, 73 of 123 patients treated with IMRT were identified as subgroup ''at risk'' for ON (> 60 Gy for oropharyngeal or oral cavity cancer). 21/73 patients were treated in a postoperative setting, 52 patients underwent primary definitive irradiation. In 56 patients concomitant cisplatin-based chemotherapy was applied. Mean follow-up time was 22 months (12-46 months). Oral cavity including the mandible bone outside the planning target volume was contoured and dose-volume constraints were defined in order to spare bone tissue. Dose-volume histograms were obtained from contoured mandible in each patient and were analyzed and related to clinical mandible bone tolerance. Results: using IMRT with doses between 60 and 75 Gy (mean 67 Gy), on average 7.8, 4.8, 0.9, and 0.3 cm{sup 3} were exposed to doses > 60, 65, 70, and 75 Gy, respectively. These values are substantially lower than when using three-dimensional conformal radiotherapy. The difference has been approximately quantified by comparison with a historic series. Additional ON risk factors of the patients were also analyzed. Only one grade 3 ON of the lingual horizontal branch, treated with

  15. Relationships between Serum Levels of Atazanavir and Renal Toxicity or Lithiasis

    OpenAIRE

    Marinescu, C. I.; Leyes, M.; M. A. Ribas; Peñaranda, M.; Murillas, J.; Campins, A. A.; Martin-Pena, L.; Barcelo, B.; Barceló-Campomar, C.; Grases, F.; Frontera, G; Melchor Riera Jaume

    2015-01-01

    The main aim of this study is to describe the relationship between serum levels of atazanavir, renal toxicity, and lithiasis. This is a prospective observational study of patients being treated with atazanavir (ATV) at Son Espases Teaching Hospital, Palma de Mallorca, between 2011 and 2013. The study includes 98 patients. Sixteen were found to have a history of urolithiasis. During a median monitoring period of 23 months, nine patients suffered renal colic, in three of whom ATV crystals were ...

  16. Radiative Symmetry Breaking in the Supersymmetric Minimal B-L Extended Standard Model

    CERN Document Server

    Burell, Zachary

    2016-01-01

    The Standard Model (SM) of particle physics is a precise model of electroweak interactions, however there is growing tension between the SM and observations (neutrino oscillations, dark matter, dark energy, baryogenesis, among others). There is no reason to expect the validity of the ad hoc SM to remain intact at energy scales above a few TeV, thus a more fundamental theory will almost certainly be required. Motivated by these considerations, we investigate a Supersymmetric version of a natural extension of the SM, the $U(1)_{B-L}$ model, that is obtained by gauging the accidental B-L symmetry that exists in the ordinary SM. The Supersymmetric $U(1)_{B-L}$ extended SM can resolve the neutrino mass problem, the dark matter problem, the hierarchy problem, and provides a mechanism for establishing the observed baryon asymmetry of the Universe. When we include quantum corrections to the Higgs potential of the model, we find that Radiative $B-L$ symmetry breaking occurs through the interplay between large Majorana...

  17. Renormalization Group Study of the Minimal Majoronic Dark Radiation and Dark Matter Model

    CERN Document Server

    Chang, We-Fu

    2016-01-01

    We study the 1-loop renormalization group equation running in the simplest singlet Majoron model constructed by us earlier to accommodate the dark radiation and dark matter content in the universe. A comprehensive numerical study was performed to explore the whole model parameter space. A smaller effective number of neutrinos $\\triangle N_{eff}\\sim 0.05$, or a Majoron decoupling temperature higher than the charm quark mass, is preferred. We found that a heavy scalar dark matter, $\\rho$, of mass $1.5-4$ TeV is required by the stability of the scalar potential and an operational type-I see-saw mechanism for neutrino masses. A neutral scalar, $S$, of mass in the $10-100$ GeV range and its mixing with the standard model Higgs as large as $0.1$ is also predicted. The dominant decay modes are $S$ into $b\\bar{b}$ and/or $\\omega\\omega$. A sensitive search will come from rare $Z$ decays via the chain $Z\\rightarrow S+ f\\bar{f}$, where $f$ is a Standard Model fermion, followed by $S$ into a pair of Majoron and/or b-quar...

  18. Charged fermions tunneling radiation from the charged Gdel black hole in minimal five-dimensional gauged supergravity

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this paper,we extend fermions tunneling radiation to the case of five-dimensional charged black holes by introducing a set of appropriate matrices γμ for general covariant Dirac equation of 1/2 spin charged Dirac particles in the electromagnetic field.It is expected that our result can strengthen the validity and power of the tunneling method.We take the charged Gdel black holes in minimal five-dimensional gauged supergravity for example in order to present a reasonable extension of the tunneling method.As a result,we get fermions tunneling probability of the black hole and the Hawking temperature near the event horizon.

  19. Using TraFiC 4 to calculate and minimize emittance growth due to coherent synchrotron radiation

    Science.gov (United States)

    Kabel, A.; Dohlus, M.; Limberg, T.

    2000-11-01

    Coherent synchrotron radiation occurs when short bunches travel on strongly bent trajectories. Its effects on high-quality beams can be severe and are well understood qualitatively. For quantitative results, however, one has to rely on numerical methods. The recent interest in high quality, high-current electron beams has generated considerable efforts to understand and minimize the effects of CSR on beam quality. By now several simulation codes, utilizing different approaches and making different approximations, exist. We describe in some detail the coder TraFiC 4 developed at DESY for design and analysis purposes. It calculates the fields acting on the pariticles from first principles and tracks particles through them in the laboratory frame. We present calculational results for three applications and give some comparison with experimental data.

  20. Radiation dose reduction in CT fluoroscopy-guided lumbar interlaminar epidural steroid injection by minimizing preliminary planning imaging

    Energy Technology Data Exchange (ETDEWEB)

    Paik, Nam Chull [Arumdaun Wooldul Spine Hospital, Department of Radiology, Ulsan (Korea, Republic of)

    2014-09-15

    To test whether radiation dose reduction in CTF-guided LIESI would be achieved by replacing the preliminary planning CT with a spot CTF while still maintaining technical performance. This retrospective study included a review of 247 consecutive procedures performed on 241 patients before (comparison group: n = 124) and after (study group: n = 123) instituting the above-mentioned the protocol modification. The patient (age, sex, body diameter, and level injected) and performance (procedure time, number of CTF acquisitions, and DLP) characteristics were compared between the two groups. The total DLP of the study group (median 4.94 mGy . cm) was significantly reduced compared to that of the comparison group (median 31.78 mGy . cm, P < 0.001). The numbers of CTF acquisitions needed for needle placement and epidurography were very similar for both groups (median 3, P = 0.685). The mean procedure time was significantly shorter for the study group (5:14 ± 1:06 min) compared to the comparison group (5:53 ± 1:19 min, P < 0.001). When conducting CTF-guided LIESIs, a significant radiation dose reduction (median 84.5 % in DLP, P < 0.001) can be achieved by minimizing the preliminary planning examination, without compromising the number of CTF acquisitions and the procedure time. (orig.)

  1. Sialendoscopy and Combined Minimally Invasive Treatment for Large Parotid Stones

    Science.gov (United States)

    Zavázalová, Šárka; Vorobiov, Olexii; Astl, Jaromír

    2016-01-01

    Sialendoscopy (SE) represents nowadays one of the standard diagnostic and therapeutic procedures in the treatment of major salivary glands lithiasis. We know from experience that it is successful only in small percentage of patients, when used in monotherapy. However, it represents an indispensable part of all of the combined minimally invasive gland-preserving treatment techniques, the success rate of which is around 90%. In this work, we focused on the role of sialendoscopy in the treatment of patients with larger inflamed fixed stones in glandula parotis. We conducted a total of 364 sialendoscopy procedures in 332 patients on our site. We have confirmed lithiasis as a cause of salivary gland obstruction in 246 (74%) patients. In 9 patients there was larger, single, or multiple inflamed fixed lithiasis of glandula parotis. In this subgroup of patients endoscopically assisted sialolithectomy from external mini-incision has become the method of choice. In 9 of the 9 (100%) cases we have achieved complete elimination of stones, and in 8 of the 9 (89%) cases we have achieved complete elimination of complaints. Sialoendoscopically assisted sialolithectomy of glandula parotis from external mini-incision has proved to be highly effective technique to eliminate stones with minimal complications. PMID:27882318

  2. Computed tomography for preoperative planning in minimal-invasive total hip arthroplasty: Radiation exposure and cost analysis

    Energy Technology Data Exchange (ETDEWEB)

    Huppertz, Alexander, E-mail: Alexander.Huppertz@charite.de [Imaging Science Institute Charite Berlin, Robert-Koch-Platz 7, D-10115 Berlin (Germany); Department of Radiology, Medical Physics, Charite-University Hospitals of Berlin, Chariteplatz 1, D-10117 Berlin (Germany); Radmer, Sebastian, E-mail: s.radmer@immanuel.de [Department of Orthopedic Surgery and Rheumatology, Immanuel-Krankenhaus, Koenigstr. 63, D-14109, Berlin (Germany); Asbach, Patrick, E-mail: Patrick.Asbach@charite.de [Department of Radiology, Medical Physics, Charite-University Hospitals of Berlin, Chariteplatz 1, D-10117 Berlin (Germany); Juran, Ralf, E-mail: ralf.juran@charite.de [Department of Radiology, Medical Physics, Charite-University Hospitals of Berlin, Chariteplatz 1, D-10117 Berlin (Germany); Schwenke, Carsten, E-mail: carsten.schwenke@scossis.de [Biostatistician, Scossis Statistical Consulting, Zeltinger Str. 58G, D-13465 Berlin (Germany); Diederichs, Gerd, E-mail: gerd.diederichs@charite.de [Department of Radiology, Medical Physics, Charite-University Hospitals of Berlin, Chariteplatz 1, D-10117 Berlin (Germany); Hamm, Bernd, E-mail: Bernd.Hamm@charite.de [Department of Radiology, Medical Physics, Charite-University Hospitals of Berlin, Chariteplatz 1, D-10117 Berlin (Germany); Sparmann, Martin, E-mail: m.sparmann@immanuel.de [Department of Orthopedic Surgery and Rheumatology, Immanuel-Krankenhaus, Koenigstr. 63, D-14109, Berlin (Germany)

    2011-06-15

    Computed tomography (CT) was used for preoperative planning of minimal-invasive total hip arthroplasty (THA). 92 patients (50 males, 42 females, mean age 59.5 years) with a mean body-mass-index (BMI) of 26.5 kg/m{sup 2} underwent 64-slice CT to depict the pelvis, the knee and the ankle in three independent acquisitions using combined x-, y-, and z-axis tube current modulation. Arthroplasty planning was performed using 3D-Hip Plan (Symbios, Switzerland) and patient radiation dose exposure was determined. The effects of BMI, gender, and contralateral THA on the effective dose were evaluated by an analysis-of-variance. A process-cost-analysis from the hospital perspective was done. All CT examinations were of sufficient image quality for 3D-THA planning. A mean effective dose of 4.0 mSv (SD 0.9 mSv) modeled by the BMI (p < 0.0001) was calculated. The presence of a contralateral THA (9/92 patients; p = 0.15) and the difference between males and females were not significant (p = 0.08). Personnel involved were the radiologist (4 min), the surgeon (16 min), the radiographer (12 min), and administrative personnel (4 min). A CT operation time of 11 min and direct per-patient costs of 52.80 Euro were recorded. Preoperative CT for THA was associated with a slight and justifiable increase of radiation exposure in comparison to conventional radiographs and low per-patient costs.

  3. Evaluation of different doses of gamma radiation on physicochemical characteristics of peach Prunus persica (cv. Chimarrita) minimally processed

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Ana Claudia S.; Silva, Lucia C.A.S.; Perecin, Thalita Neme; Arthur, Valter; Harder, Marcia N.C. [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil). Dept. de Radiobiologia e Ambiente], e-mail: acsoliveira@usp.br, e-mail: arthur@cena.usp.br; Mansi, Debora N.; Canniatti-Brazaca, Solange G. [Escola Superior de Agricultura Luiz de Queiroz (ESALQ/USP), Piracicaba, SP (Brazil). Dept. de Agroindustria, Alimentos e Nutricao

    2009-07-01

    The objective was to evaluate the effect of different doses of gamma radiation on the physico-chemical characteristics of peach Prunus persica (cv. Chimarrita) minimally processed, to increase the useful life of the fruit. The peaches were purchased at Ceasa of Campinas/SP and taken to the Laboratory of Radiobiology and Environment of CENA/USP (Piracicaba/SP), which were washed in tap water, peeled and cut into four pieces. The pieces of peach were dipped in sodium hypochlorite solution of 15 mL/L for 4 minutes and dry in a plastic support. Then it were placed in plastic containers (polypropylene). Subsequently, they were irradiated in a Cobalt-60 source, type Gammacell-220 (dose rate of 0,543 kGy/hour) with doses of: 0 (control), 1.0 and 2.0 kGy and stored at a temperature of 8 deg C. The experimental was developed entirely at random with 3 replicates for each treatment. For the statistic analysis was using the Tuckey test at 5% level of probability. Subsequently, analysis was carried out: color factors (l, a, b), pH, soluble solids (deg Brix), acidity and vitamin C. The tests were performed at 1, 3 and 6 days after irradiation. According to the results concluded that the analysis of color and acidity there was no significant difference between treatments, however, for the soluble solids (deg Brix), vitamin C and texture significant difference showing a decrease proportional to increasing doses of radiation and storage time. But the pH increased in relation to dose and during the analysis. (author)

  4. Computed tomography for preoperative planning in minimal-invasive total hip arthroplasty: radiation exposure and cost analysis.

    Science.gov (United States)

    Huppertz, Alexander; Radmer, Sebastian; Asbach, Patrick; Juran, Ralf; Schwenke, Carsten; Diederichs, Gerd; Hamm, Bernd; Sparmann, Martin

    2011-06-01

    Computed tomography (CT) was used for preoperative planning of minimal-invasive total hip arthroplasty (THA). 92 patients (50 males, 42 females, mean age 59.5 years) with a mean body-mass-index (BMI) of 26.5 kg/m(2) underwent 64-slice CT to depict the pelvis, the knee and the ankle in three independent acquisitions using combined x-, y-, and z-axis tube current modulation. Arthroplasty planning was performed using 3D-Hip Plan(®) (Symbios, Switzerland) and patient radiation dose exposure was determined. The effects of BMI, gender, and contralateral THA on the effective dose were evaluated by an analysis-of-variance. A process-cost-analysis from the hospital perspective was done. All CT examinations were of sufficient image quality for 3D-THA planning. A mean effective dose of 4.0 mSv (SD 0.9 mSv) modeled by the BMI (p<0.0001) was calculated. The presence of a contralateral THA (9/92 patients; p=0.15) and the difference between males and females were not significant (p=0.08). Personnel involved were the radiologist (4 min), the surgeon (16 min), the radiographer (12 min), and administrative personnel (4 min). A CT operation time of 11 min and direct per-patient costs of 52.80 € were recorded. Preoperative CT for THA was associated with a slight and justifiable increase of radiation exposure in comparison to conventional radiographs and low per-patient costs.

  5. Urinary lithiasis and idiopathic hypercalciuria: the importance of dietary intake evaluation

    Directory of Open Access Journals (Sweden)

    Patricia C. G. Damasio

    2010-10-01

    Full Text Available PUSPOSE: To evaluate food intake of patients with urinary lithiasis and idiopathic hypercalciuria (IH. MATERIALS AND METHODS: Between August 2007 and June 2008, 105 patients with lithiasis were distributed into 2 groups: Group 1 (n = 55 - patients with IH (urinary calcium excretion > 250 mg in women and 300 mg in men with normal serum calcium; Group 2 (n = 50 - normocalciuria (NC patients . Inclusion criteria were: age over 18, normal renal function (creatinine clearance = 60 mL/min, absent proteinuria and negative urinary culture. Pregnant women, patients with some intestinal pathology, chronic diarrhea or using corticoids were excluded. The protocol of metabolic investigation was based on non-consecutive collection of two 24-hour samples for dosages of: calcium, sodium, uric acid, citrate, oxalate, magnesium and urinary volume. Food intake was evaluated through the quantitative method of Dietary Register of three days. RESULTS: Urinary excretion of calcium (433.33 ± 141.92 vs. 188.93 ± 53.09, sodium (280.08 ± 100.94 vs. 200.44.93 ± 65.81, uric acid (880.63 ± 281.50 vs. 646.74 ± 182.76 and magnesium (88.78 ± 37.53 vs. 64.34 ± 31.84 was significantly higher in the IH group in comparison to the NC group (p < 0.05. As regards the nutritional composition of food intake of IH and NC groups, there was no statistical significant difference in any nutrient evaluated. CONCLUSION: In our study, no difference was observed in the food intake of patients with urinary lithiasis and IH or NC.

  6. Hypercalciuria, hyperoxaluria, and hypocitraturia screening from random urine samples in patients with calcium lithiasis.

    Science.gov (United States)

    Arrabal-Polo, Miguel Angel; Arias-Santiago, Salvador; Girón-Prieto, María Sierra; Abad-Menor, Felix; López-Carmona Pintado, Fernando; Zuluaga-Gomez, Armando; Arrabal-Martin, Miguel

    2012-10-01

    Calcium lithiasis is the most frequently diagnosed renal lithiasis and is associated with a high percentage of patients with metabolic disorders, such as hypercalciuria, hypocitraturia, and hyperoxaluria. The present study included 50 patients with recurrent calcium lithiasis. We conducted a random urine test during nocturnal fasting and a 24-h urine test, and examined calcium, oxalate, and citrate. A study of the linear correlation between the metabolites was performed, and the receiver operator characteristic (ROC) curves were analyzed in the random urine samples to determine the cutoff values for hypercalciuria (excretion greater than 200 mg), hyperoxaluria (excretion greater than 40 mg), and hypocitraturia (excretion less than 320 mg) in the 24-h urine. Linear relationships were observed between the calcium levels in the random and 24-h urine samples (R = 0.717, p = 0.0001), the oxalate levels in the random and 24-h urine samples (R = 0.838, p = 0.0001), and the citrate levels in the random and 24-h urine samples (R = 0.799, p = 0.0001). After obtaining the ROC curves, we observed that more than 10.15 mg/dl of random calcium and more than 16.45 mg/l of random oxalate were indicative of hypercalciuria and hyperoxaluria, respectively, in the 24-h urine. In addition, we found that the presence of less than 183 mg/l of random citrate was indicative of the presence of hypocitraturia in the 24-h urine. Using the proposed values, screening for hypercalciuria, hyperoxaluria, and hypocitraturia can be performed with a random urine sample during fasting with an overall sensitivity greater than 86%.

  7. Urinary supersaturation with respect to brushite in patients suffering calcium oxalate lithiasis.

    Science.gov (United States)

    Berland, Y; Boistelle, R; Olmer, M

    1990-01-01

    The urines of 23 stone-formers presenting repeated calcium oxalate lithiasis and 12 control subjects were collected at six different time periods daily. Supersaturations for calcium oxalate and brushite (DCPD) were calculated using ionic and solubility products. Urines of both groups were supersaturated for calcium oxalate but only urines of the stone-formers were supersaturated for brushite, the most simple calcium phosphate which nucleates very easily at the urinary pH. This fact suggests that the core of the calcium oxalate stone could be made of either a calcium oxalate crystallite or a brushite seed onto which hetergeneous nucleation of calcium oxalate can take place.

  8. The Prevalence of Urinary Lithiasis in Children in Van Region, Turkey

    OpenAIRE

    Akgun, Cihangir; Kayan, Mustafa; Tuncer, Oguz; Arslan, Sukru; Caksen, Huseyin; Atas, Bulent; Akbayram, Sinan

    2009-01-01

    We aimed to determine the prevalence and etiology of urinary lithiasis in childhood in our region, Van, Turkey. A total of 1120 children were included in the study. Urinary ultrasonography was performed in all the children between April 2003 and June 2003. During the study, the kidneys were examined longitudinally and transversally using a 3.75 MHz convex probe in a Hitachi EUB -315 ultrasonography machine. The children's ages ranged from 7 years to 14 years (10.16 ± 1.92 years) and 572 (51.1...

  9. Does bilioenteric anastomosis impair results of liver resection in primary intrahepatic lithiasis?

    Institute of Scientific and Technical Information of China (English)

    Paulo; Herman; Marcos; V; Perini; Vincenzo; Pugliese; Julio; Cesar; Pereira; Marcel; Autran; C; Machado; William; A; Saad; Luiz; AC; D; Albuquerque; Ivan; Cecconello

    2010-01-01

    AIM:To evaluate the long-term results of liver resection for the treatment of primary intrahepatic lithiasis.Prognostic factors,especially the impact of bilioenteric anastomosis on recurrence of symptoms were assessed.METHODS:Forty one patients with intrahepatic stones and parenchyma fibrosis/atrophy and/or biliary stenosis were submitted to liver resection.Resection was associated with a Roux-en-Y hepaticojejunostomy in all patients with bilateral stones and in those with unilateral disease and dilation of...

  10. [Treatment of renoureteral lithiasis using extracorporeal shockwave lithotripsy. Experience in Cuba].

    Science.gov (United States)

    Larrea Masvidal, E; García Serrano, C; Hernández Silverio, D; Castillo Rodríguez, M; Casals Armada, J; Valdés Gómez, C; Báez Hernández, D

    1989-01-01

    Herein we present our experience in 5,000 cases of reno-ureteral lithiasis submitted to treatment at the Extracorporeal Lithotripsy Unit of Hermanos Ameijeiras Hospital in Havana, Cuba, from April 1986 and during a period spanning 30 months. Treatment was exclusively by extracorporeal shock wave lithotripsy (ESWL) in 85.5% of the patients and in combination with other procedures in 14.5% (endoscopic maneuvers in 5.9%, percutaneous nephrostomy 4.4%, open surgery 3.6%, and percutaneous nephrolithotripsy 0.6%). Complications were observed in 7% of the cases: ureteric obstruction (6.4%) with or without infection, perirenal hematoma (0.4%), and obstructive anuria (0.2%); acute urinary infection of different clinical types, some of which were very severe, were observed concomitantly in 2.6% of these patients. Two months following treatment, 86% of the cases were completely stone-free. At 6 months 96.2% were completely stone-free; the remaining 3.8% were classed as residual lithiasis. The pathologic conditions that put patients at high therapeutic risk and the possible complications that could arise were identified. The efficacy of the Dornier HM-3 lithotripter and the health care system that permits its extensive use are highlighted.

  11. Extracorporeal shock waves lithotripsy versus retrograde ureteroscopy: is radiation exposure a criterion when we choose which modern treatment to apply for ureteric stones?

    Directory of Open Access Journals (Sweden)

    Catalin Pricop

    2014-10-01

    Full Text Available The aim of this study is to compare two major urological procedures in terms of patient exposure to radiation. We evaluated 175 patients, that were subjected to retrograde ureteroscopy (URS and extracorporeal shock waves lithotripsy (ESWL for lumbar or pelvic ureteral lithiasis, at two urological departments. The C-arm Siemens (produced in 2010 by Siemens AG, Germany was used for ureteroscopy. The radiological devices of the lithotripters used in this study in the two clinical centers had similar characteristics. We evaluated patient exposure to ionizing radiation by using a relevant parameter, the air kerma-area product (PKA; all values in cGy cm2, calculated from the radiation dose values recorded by the fluoroscopy device. PKA depends on technical parameters that change due to anatomical characteristics of each case examined, such as body mass index (BMI, waist circumference, and stone location. For the patients subjected to ESWL for lumbar ureteral lithiasis the mean of PKA (cGy cm2 was 509 (SD=180, while for those treated for pelvic ureteral lithiasis the mean of PKA was 342 (SD=201. In the URS group for lumbar ureteral lithiasis, the mean of PKA (cGy cm2 was 892 (SD=436, while for patients with pelvic ureteral lithiasis, the mean of PKA was 601 (SD=429. The patients treated by URS had higher exposure to ionizing radiation dose than patients treated by ESWL. The risk factors of higher radiation doses were obesity, exposure time, and localization of the stones.

  12. Urinary lithiasis in civil construction workers as a management indicator for health and improvement in personnel

    Directory of Open Access Journals (Sweden)

    Renato Ribeiro Nogueira Ferraz

    2014-12-01

    Full Text Available Introduction: Empirical information provided by health care professionals acting in the first line of care report a constant increase in the number of civil construction workers that present painful acute conditions, in most cases associated with the existence of urinary tract calculi. Aims: Evaluating the prevalence of urinary lithiasis in civil construction workers, as a means to identify indicators for the management of health and personnel. Methods: Observational study based on directed questionnaire. Results: From the 94 participants, 18 (19% were lithiasic, mostly due to overweight and reduced fluid intake. Conclusion: The observed prevalence appeared to be two times greater than that of the general population. Thus, prevention for such condition gains relevance, in order to avoid discomfort for the worker, and also reduce costs due to absenteeism, improving productivity, benefiting the workers by performance and creating the perspective of an improved quality of life.

  13. THE ROLE OF BELARUS NATIONAL COMMISSION ON RADIATION PROTECTION IN THE MINIMIZATION OF CONSEQUENCES OF THE ACCIDENT AT THE CHERNOBYL NUCLEAR POWER PLANT

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    A. N. Stozharov

    2016-01-01

    Full Text Available The Belarus National Commission on Radiation Protection was established in 1991, based on the former Byelorussian Soviet Socialist Republic Supreme Council Resolution. The Commission works out recommendations on the radiation protection to submit to the state authorities, state institutions under the Republic of Belarus Government and state research institutions, reviews and assesses scientific data in the field of radiation protection and makes suggestions in regards of the implementation of the achieved developments. The Commission engages leading scientists and practitioners from Belarus, involved in the provision of the radiation protection and safety in the state. The methodological cornerstone for the Commission activities was chosen to be the committment to the worldwide accepted approach of the nature and magnitude of the undertaken protective measures justification in the field of radiation safety. The Commission adheres the ALARA optimization criteria as the core of the aforementioned approach. The Commission has also submited to the Government a number of developments which were crucial in the highest level managerial decisions elaboration. The latter impacted directly the state tactics and strategy in the environmental, health and social consequences of the Chernobyl disaster minimization. Following the recommendations of the international institutions (ICRP, IAEA, UNSCEAR, FAO/WHO, developments of the colleagues in the Russian Federation, Ukraine and the local regional experience, the Commission proceeds with the expert observation of the ongoing protective measures to reduce the radiation impact and population exposure resulted from the Chernobyl accident, is actively occupied in the radiation safety ensuring at the Belarussian nuclear power plant being under construction, much contributes to elaboration of the new version of the state Law “On Radiation Protection of Population” and other regulatory documents.

  14. Sulfadiazine-related obstructive urinary tract lithiasis: an unusual cause of acute renal failure after kidney transplantation.

    Science.gov (United States)

    Guitard, J; Kamar, N; Mouzin, M; Borde, J S; Tran-Van, T; Durand, D; Rostaing, L

    2005-05-01

    We report on the first case of acute renal failure related to obstructive urinary tract lithiasis involving sulfadiazine crystals in a kidney transplant recipient. This patient had disseminated toxoplasmosis which was treated by sulfadiazine (4 g/day) and pyrimethamine (50 mg/day). In the fourth week of anti-toxoplasmosis therapy, he presented with obstructive acute renal failure: the plasma creatinine level increased from 220 micromol/l to 547 micromol/l. Apercutaneous pyelography was conducted showing the presence of a lithiasis located at the junction between the graft ureter and the bladder. Six days later, he underwent surgery to retrieve an orange-colored, friable stone. Its spectrophotometric analysis confirmed that the stone consisted of N-acetyl sulfadiazine crystals.

  15. Radiation processing to ensure safety of minimally processed carrot (Daucus carota) and cucumber (Cucumis sativus): optimization of dose for the elimination of Salmonella Typhimurium and Listeria monocytogenes.

    Science.gov (United States)

    Dhokane, V S; Hajare, S; Shashidhar, R; Sharma, A; Bandekar, J R

    2006-02-01

    Minimally processed vegetables are in demand, because they offer convenience to consumers. However, these products are often unsafe because of possible contamination with pathogens, such as Salmonella, Escherichia coli O157:H7, and Shigella species. Therefore, this study was carried out to optimize the radiation dose necessary to ensure the safety of precut carrot and cucumber. Decimal reduction doses (D-values) of Salmonella Typhimurium MTCC 98 were ca. 0.164 kGy in carrot samples and 0.178 kGy in cucumber samples. D-values of Listeria monocytogenes were determined to be 0.312 and 0.345 kGy in carrot and cucumber samples, respectively. Studies of inoculated, packaged, minimally processed carrot and cucumber samples showed that treatment with a 1-kGy dose of gamma radiation eliminated up to 4 log CFU/g of Salmonella Typhimurium and 3 log CFU/g of L. monocytogenes. However, treatment with a 2-kGy dose was necessary to eliminate these pathogens by 5 log CFU/g. Storage studies showed that both Salmonella Typhimurium and L. monocytogenes were able to grow at 10 degrees C in inoculated control samples. Neither of these pathogens could be recovered from radiation-processed samples after storage for up to 8 days.

  16. Minimal Pairs: Minimal Importance?

    Science.gov (United States)

    Brown, Adam

    1995-01-01

    This article argues that minimal pairs do not merit as much attention as they receive in pronunciation instruction. There are other aspects of pronunciation that are of greater importance, and there are other ways of teaching vowel and consonant pronunciation. (13 references) (VWL)

  17. Application of the microbiological method DEFT/APC to detect minimally processed vegetables treated with gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, M.M.; Duarte, R.C.; Silva, P.V. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Centro de Tecnologia das Radiacoes, Laboratorio de Deteccao de Alimentos Irradiados, Cidade Universitaria, Av. Prof. Lineu Prestes 2242, Butanta Zip Code 05508-000 Sao Paulo (Brazil); Marchioni, E. [Laboratoire de Chimie Analytique et Sciences de l' Aliment (UMR 7512), Faculte de Pharmacie, Universite Louis Pasteur, 74, route du Rhin, F-67400 Illkirch (France); Villavicencio, A.L.C.H. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Centro de Tecnologia das Radiacoes, Laboratorio de Deteccao de Alimentos Irradiados, Cidade Universitaria, Av. Prof. Lineu Prestes 2242, Butanta Zip Code 05508-000 Sao Paulo (Brazil)], E-mail: villavic@ipen.br

    2009-07-15

    Marketing of minimally processed vegetables (MPV) are gaining impetus due to its convenience, freshness and apparent health effect. However, minimal processing does not reduce pathogenic microorganisms to safe levels. Food irradiation is used to extend the shelf life and to inactivate food-borne pathogens. In combination with minimal processing it could improve safety and quality of MPV. A microbiological screening method based on the use of direct epifluorescent filter technique (DEFT) and aerobic plate count (APC) has been established for the detection of irradiated foodstuffs. The aim of this study was to evaluate the applicability of this technique in detecting MPV irradiation. Samples from retail markets were irradiated with 0.5 and 1.0 kGy using a {sup 60}Co facility. In general, with a dose increment, DEFT counts remained similar independent of the irradiation while APC counts decreased gradually. The difference of the two counts gradually increased with dose increment in all samples. It could be suggested that a DEFT/APC difference over 2.0 log would be a criteria to judge if a MPV was treated by irradiation. The DEFT/APC method could be used satisfactorily as a screening method for indicating irradiation processing.

  18. [Biochemical effects of potassium citrate in the treatment of calcium oxalate lithiasis].

    Science.gov (United States)

    Conte Visús, A; Ibarz Servio, L; Arrabal Martín, M; Ibarz Navarro, J M; Ruiz Marcellán, F J

    1994-03-01

    The serum and urinary biochemical changes observed one month and six months after oral potassium citrate therapy (600 mEq/day) in 119 patients with calcium oxalate calculi were compared with those of 16 untreated cases with lithiasis. The patients that received treatment were previously divided into two groups: group A comprised 61 hypocitraturic patients and group B comprised 58 patients with other urinary disorders who were normo or hypocitraturic. The urinary pH increased by approximately half a point in both treated groups. In group A calciuria increased slightly from 180 +/- 8 to 216 +/- 10 mg/24 h but remained within the normal ranges. Creatinuria, oxaluria, uricosuria and diuresis showed no changes. Citraturia increased very significantly in both groups and more markedly in the hypocitraturic group of patients (from 198 +/- 13 to 476 +/- 35 mg/24 h). The LRC (lithogenic risk coefficient = Ca/Cit x Diu) dropped by 50%. The patients tolerated the treatment regimen well; of the 119 treated patients, only 11 abandoned treatment due to GI intolerance.

  19. Anti Lithiasis Activity of Avocado (Persea americana Mill Leaves Extract in White Male Rats

    Directory of Open Access Journals (Sweden)

    IETJE WIENTARSIH

    2012-03-01

    Full Text Available In Indonesia, avocado leaves have been used as traditional medicines for diureticum to cure urolithiasis. This research was to determine anti lithiasis activity of avocado leaves (Persea americana Mill extract on white male rats nefrolithiasis model induced by ethylene glycol. Ethanol extraction method was used to get extract of avogadro leaves. Twenty adult male white rats were divided into 4 different induction treatments i.e. aquadest, ethylene glycol 0.75% and ammonium chloride 2%, and extract of avocado leaves with different levels of 100 and 300 mg/kg bw respectively. Their body weight was measured daily to determine their growth ratio. And at the end of the trial, the kidney was analyzed its calcium level and inhibitory activity to formation of calcium oxalate crystals. The results showed that the amount of calcium level in the kidney of rats treated with extract of avogadro leaves was significantly decreased than that of rats treated with ethylene glycol 0.75% and ammonium chloride 2% (P < 0.05. The extract avocado leaves as a herbal remedy can be recommended as a phytotherapeutic agent especially for preventive action for urolithiasis diseases.

  20. Relationships between Serum Levels of Atazanavir and Renal Toxicity or Lithiasis

    Directory of Open Access Journals (Sweden)

    C. I. Marinescu

    2015-01-01

    Full Text Available The main aim of this study is to describe the relationship between serum levels of atazanavir, renal toxicity, and lithiasis. This is a prospective observational study of patients being treated with atazanavir (ATV at Son Espases Teaching Hospital, Palma de Mallorca, between 2011 and 2013. The study includes 98 patients. Sixteen were found to have a history of urolithiasis. During a median monitoring period of 23 months, nine patients suffered renal colic, in three of whom ATV crystals were evidenced in urine. Cumulative incidence of renal colic was 9.2 per 100 patients. The variables related to having renal colic were the presence of alkaline urine pH and lower basal creatinine clearance. The mean serum level of ATV was slightly higher in patients with renal colic—1,303 μg/L versus 1,161 μg/L—but did not reach statistical significance. Neither were any significant differences detected by analysing the levels according to the timetable for ATV dosage. Cumulative incidence of renal colic was high in patients being treated with ATV, in 33% of whom the presence of ATV crystals was evidenced in urine. We were unable to demonstrate a relationship between ATV serum levels and renal colic or progression towards renal failure.

  1. ANTILITHIATIC ACTIVITY OF Saccharum spontaneum Linn. ON ETHYLENE GLYCOL – INDUCED LITHIASIS IN RATS.

    Directory of Open Access Journals (Sweden)

    M.Sathya

    2012-09-01

    Full Text Available The ethanolic extract of roots of Saccharum spontaneum Linn. was evaluated for its antilithiatic activity in rats. Lithiasis was induced by oral administration of ethylene glycolated water (0.75% in adult male wistar albino rats for 28 days. The ionic chemistry of urine was altered by ethylene glycol (EG, which elevated the urinary concentration of crucial ions, viz. calcium, phosphorus and protein thereby contributing to renal stone formation. However treatment with ethanolic root extract of S.spontaneum (200 and 300 mg / kg bodyweight in group III and IV significantly (p<0.05 reduced the elevated level of these ions in urine. The levels of serum urea, uric acid and creatinine were significantly increased (p < 0.05 in urolithiatic rats. Treatment with plant extract restored the levels and it brought back the values to near normal range in urolithiatic rats. All these observations revealed that ethanolic root extract of S.spontaneum has curative effect on stone formation induced by ethylene glycol.

  2. Relationships between Serum Levels of Atazanavir and Renal Toxicity or Lithiasis.

    Science.gov (United States)

    Marinescu, C I; Leyes, M; Ribas, M A; Peñaranda, M; Murillas, J; Campins, A A; Martin-Pena, L; Barcelo, B; Barceló-Campomar, C; Grases, F; Frontera, G; Riera Jaume, Melchor

    2015-01-01

    The main aim of this study is to describe the relationship between serum levels of atazanavir, renal toxicity, and lithiasis. This is a prospective observational study of patients being treated with atazanavir (ATV) at Son Espases Teaching Hospital, Palma de Mallorca, between 2011 and 2013. The study includes 98 patients. Sixteen were found to have a history of urolithiasis. During a median monitoring period of 23 months, nine patients suffered renal colic, in three of whom ATV crystals were evidenced in urine. Cumulative incidence of renal colic was 9.2 per 100 patients. The variables related to having renal colic were the presence of alkaline urine pH and lower basal creatinine clearance. The mean serum level of ATV was slightly higher in patients with renal colic-1,303 μg/L versus 1,161 μg/L-but did not reach statistical significance. Neither were any significant differences detected by analysing the levels according to the timetable for ATV dosage. Cumulative incidence of renal colic was high in patients being treated with ATV, in 33% of whom the presence of ATV crystals was evidenced in urine. We were unable to demonstrate a relationship between ATV serum levels and renal colic or progression towards renal failure.

  3. [Biliary lithiasis in patients over 75. 100 cases operated upon (author's transl)].

    Science.gov (United States)

    Moreaux, J; Bonnet, J L; Gerum, A

    1982-02-27

    This is a retrospective study of 100 elderly patients (36 men and 64 women aged 75 years or more) operated upon for biliary tract calculi. Thirty-one patients had one or several underlying visceral diseases and 5 had associated carcinoma of the digestive tract. Calculi of the common bile duct were present in 48 cases, and 41 patients had acute infection, including cholecystitis (14) and cholangitis (27). Surgery included cholecystectomy in every case and opening of the common bile duct in 49 cases with either choledocho-duodenal anastomosis (31 cases) or external biliary drainage (18 cases). Only one patient with gastric carcinoma died. The morbidity rate was low (11 post-operative complications) and each group of patients spent about the same time in hospital. Neither mortality nor morbidity were aggravated by the presence of calculi in the common bile duct and/or acute infection. In uncomplicated lithiasis the surgical indications mainly depend upon the severity of underlying visceral diseases. Early intervention seems desirable in most patients with acute cholecystitis or cholangitis. Surgery of the biliary tract is basically the same in elderly and in young patients, but the operation must be simple and, if possible, complete. The quality of medical surveillance and nursing has considerable influence on the results.

  4. Minimal skin dose increase in longitudinal rotating biplanar linac-MR systems: examination of radiation energy and flattening filter design

    Science.gov (United States)

    Keyvanloo, A.; Burke, B.; St. Aubin, J.; Baillie, D.; Wachowicz, K.; Warkentin, B.; Steciw, S.; Fallone, B. G.

    2016-05-01

    The magnetic fields of linac-MR systems modify the path of contaminant electrons in photon beams, which alters patient entrance skin dose. Also, the increased SSD of linac-MR systems reduces the maximum achievable dose rate. To accurately quantify the changes in entrance skin dose, the authors use EGSnrc Monte Carlo calculations that incorporate 3D magnetic field of the Alberta 0.5 T longitudinal linac-MR system. The Varian 600C linac head geometry assembled on the MRI components is used in the BEAMnrc simulations for 6 MV and 10 MV beam models and skin doses are calculated at an average depth of 70 μm using DOSXYZnrc. 3D modeling shows that magnetic fringe fields decay rapidly and are small at the linac head. SSDs between 100 and 120 cm result in skin-dose increases of between ~6%-19% and ~1%-9% for the 6 and 10 MV beams, respectively. For 6 MV, skin dose increases from ~10.5% to ~1.5% for field-size increases of 5  ×  5 cm2 to 20  ×  20 cm2. For 10 MV, skin dose increases by ~6% for a 5  ×  5 cm2 field, and decreases by ~1.5% for a 20  ×  20 cm2 field. Furthermore, the proposed reshaped flattening filter increases the dose rate from the current 355 MU min-1 to 529 MU min-1 (6 MV) or 604 MU min-1 (10 MV), while the skin-dose increases by only an additional ~2.6% (all percent increases in skin dose are relative to D max). This study suggests that there is minimal increase in the entrance skin dose and minimal/no decrease in the dose rate of the Alberta longitudinal linac-MR system. The even lower skin dose increase at 10 MV offers further advantages in future designs of linac-MR prototypes.

  5. Comorbidity and socio-demographic factors associated with renal lithiasis in persons aged 40 to 65: A cross-sectional study.

    Science.gov (United States)

    Arias Vega, Raquel; Pérula de Torres, Luis Angel; Jiménez García, Celia; Carrasco Valiente, Julia; Requena Tapia, Maria José; Cano Castiñeira, Roque; Silva Ayçaguer, Luis Carlos

    2017-05-17

    Renal lithiasis is one of the most important urological diseases. It seems to be related to different socio-demographic and climatic factors, lifestyle and pre-existing comorbidity. The aim of this study was to examine the relationship between socio-demographic variables, certain risk factors and chronic diseases and the renal lithiasis. A cross-sectional population-based study was carried out, selecting the Spanish population aged from 40 to 65 years, combining 2 random samples (PreLiRenA and PreLiRenE studies). Data were collected by personal telephone surveys, gathering information on socio-demographic variables and perceived morbidity. Data on annual average temperatures in each Spanish region were also collected. A bivariate and multivariate analysis was performed. A total of 4,894 subjects were surveyed; 51.3% were women; 25% were aged 40-45 years, 36% had primary school education and 31.4% were of low social class. The overall prevalence of renal lithiasis was 15.0% (95% confidence interval [95% CI] 14.5-15.5). By means of multivariate analysis, the variables that showed a strong statistical relationship with the presence of renal lithiasis were: older age (61-65 years; OR=1.39; 95% CI 1.06-1.80), high social class (OR=1.98; 95% CI 1.29-2.62), family history of renal lithiasis (OR=2.22; 95% CI 1.88-2.65), high blood pressure (OR=1.68; 95% CI 1.39-2.02) and overweight/obesity (OR=1.31; 95% CI 1.12-1.54). A correlation was observed between renal lithiasis and average annual temperatures in the Spanish regions (r=0.59; P=.013). A relationship was observed between renal lithiasis and older age, belonging to higher social classes, the existence of a family history of urolithiasis, and hypertension and overweight or obesity. The prevalence of renal lithiasis is greater in warmer climate zones. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  6. Evaluation of the effects of gamma radiation on physical and chemical characteristics of pineapple (Annanas Comosus (L.) (Meer) cv. smooth Cayenne minimally processed

    Energy Technology Data Exchange (ETDEWEB)

    Perecin, Thalita N.; Oliveira, Ana Claudia S.; Silva, Lucia C.A.; Costa, Marcia H.N.; Arthur, Valter [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil). Lab. de Radiobiologia e Ambiente], e-mail: arthur@cena.usp.br

    2009-07-01

    This study aimed to evaluate the effects of gamma radiation, polypropylene packaging type and temperature (8 deg C) in the physic-chemical characteristics of pineapple 'Smooth Cayenne' minimally processed. The fruits were selected, washed, peeled, sliced crosswise into four parts and placed in sodium hypochlorite 10 ml/L for three minutes, dried and packaged. Were irradiated in a Cobalt-60 source, type Gammacell -220 (dose rate 0.543 kGy/hour), with doses of 0 (control), 1 and 2 kGy and stored in temperature of 8 deg C. Were analyzed color (L factors, a, b), pH, deg Brix, texture, during 5 days after irradiation. The experiment was entirely at random with 3 replicates for each treatment. For the statistic analysis was used the Tuckey test at 5% level of probability. (author)

  7. [A family history of renal lithiasis in children diagnosed of urinary tract infection by Escherichia coli].

    Science.gov (United States)

    García Nieto, Víctor; Sotoca Fernández, Jorge; O'Hagan, Monica; Arango Sancho, Pedro; Luis Yanes, Maria Isabel

    2017-06-03

    Urinary tract infections (UTI) caused by Escherichia coli (E. coli) are common in patients with idiopathic hypercalciuria. As both UTI and hypercalciuria (prelithiasis) have a genetic basis, we wanted to know whether the family history of urolithiasis is more common in children with UTIs caused by E. coli. Secondarily, we wondered if the renal scars are more common in children with prelithiasis. Ambispective study with collected data from 104 patients (40 male, 64 female) followed after having been diagnosed of UTI by E. coli at least once. These patients were asked about the existence of urolithiasis in relatives. The calcium and citrate urinary elimination was qunatified in 80 children. In the total sample, family history was positive for urolithiasis in a significantly higher frequency in those children (n=71; 68.3%) than in the control population in our area (29.7%; previously published data). Prelithiasis frequency in children with UTI was 47.5% (38/80). An association was observed between the diagnosis of prelithiasis both with family history of urolithiasis (P=.030) and the diagnosis of vesicoureteral reflux (P=.034). Children who developed renal scarring had an increased risk of prelithiasis (OR 5.3; P=.033). The frequency of family history of urolithiasis in children with UTI caused by E. coli is very high. Based on our results we hypothesize that the predisposition to lithiasis can involve a constitutively altered defense to E. coli and, therefore, a greater possibility for renal scars. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  8. Helicobacter species are associated with possible increase in risk of biliary lithiasis and benign biliary diseases

    Directory of Open Access Journals (Sweden)

    Pandey Manoj

    2007-08-01

    Full Text Available Abstract Background Hepato-biliary tract lithiasis is common and present either as pain or as asymptomatic on abdominal ultrasonography for other causes. Although the DNA of Helicobacter species are identified in the gallbladder bile, tissue or stones analyzed from these cases, still a causal relationship could not be established due to different results from different geographical parts. Methods A detailed search of pubmed and pubmedcentral was carried out with key words Helicobacter and gallbladder, gallstones, hepaticolithiasis, cholelithiasis and choledocholithiasis, benign biliary diseases, liver diseases. The data was entered in a data base and meta analysis was carried out. The analysis was carried out using odds ratio and a fixed effect model, 95% confidence intervals for odds ratio was calculated. Chi square test for heterogeneity was employed. The overall effect was calculated using Z test. Results A total of 12 articles were identified. One study used IgG for diagnosis while others used the PCR for Ure A gene, 16 S RNA or Cag A genes. A couple of studies used culture or histopathology besides the PCR. The cumulative results show a higher association of Helicobacter with chronic liver diseases (30.48%, and stone diseases (42.96%(OR 1.77 95% CI 1.2–2.58; Z = 2.94, p = 0.003, the effect of each could not be identified as it was difficult to isolate the effect of helicobacter due to mixing of cases in each study. Conclusion The results of present meta analysis shows that there is a slight higher risk of cholelithiasis and benign liver disease (OR 1.77, however due to inherent inability to isolate the effect of stone disease from that of other benign lesions it is not possible to say for sure that Helicobacter has a casual relationship with benign biliary disease or stone disease or both.

  9. Sphincterotomy plus large balloon dilation versus sphincterotomy alone for the extraction of complex lithiasis: a prospective analysis

    Directory of Open Access Journals (Sweden)

    Martín Alejandro Guidi

    2015-08-01

    Full Text Available Background and purpose: Mid-size sphincterotomy associated with large balloon dilation is an alternative to wide sphincterotomy to remove complex lithiases. However, which of the two techniques is most effective remains unclear. Hence, we conducted this study to compare both methods prospectively. Method: Since January 2012 until March 2014, 133 consecutive patients with complex stones were included. Group A underwent mid-size sphincterotomy associated with large balloon dilation and group B underwent wide sphincterotomy alone. Success rates were assessed for: Extraction of stones, ductal patency rate, the use of mechanical lithotripsy, dose, time and dose per radioscopy area as well as procedure-related complications. Results: Group A comprised 44 patients and group B comprised 69 patients. Overall success rate for extraction was 86.4% in group A and 70% in group B (p = 0.069. In giant lithiasis, effective extraction was 89.3% in group A and 58.6% in group B (p = 0.019. Use of mechanical lithotripsy was 15.9% and 30.4%, respectively (p = 0.142. Total radiotherapy dose was 39.8 mGy vs. 26.2 mGy, respectively (p = 0.134. Complications occurred in 6.8% and 5.5% of the procedures in each group, without significant differences among them (p = 0.856. Conclusion: Sphincterotomy plus large balloon dilation is more effective and equally safe than conventional sphincterotomy for the management of giant main bile duct lithiasis.

  10. Outcome-Based Comparison of Percutaneous Procedures for Urinary Lithiasis with Calibre of Instrumentation less than 12Fr.

    Science.gov (United States)

    Wells, H; Rukin, N; Wright, A; Somani, B K

    2015-08-01

    Renal stone disease is becoming increasingly prevalent globally. With a rise in stone disease worldwide, there is also a relative increase in the rates of surgical intervention. Technological advances have allowed a move towards minimising the complications rates and length of stay with a reduction in invasiveness and size of instruments. A trend for minimising the percutaneous tract size has been noted in percutaneous nephrolithotomy (PCNL) for renal stones. The management has shifted from open surgery to standard PCNL, mini-PCNL and the latest ultra-mini and micro-PCNL techniques. There is a need to compare outcomes for the ever-advancing technologies, such as the smaller calibre of instruments, to assess risk-benefit in practice. This review looks at outcome-based comparison of percutaneous procedures for urinary lithiasis with instruments <12Fr in size.

  11. [Update for the management of kidney stones in 2013. Lithiasis Committee of the French Association of Urology].

    Science.gov (United States)

    Carpentier, X; Meria, P; Bensalah, K; Chabannes, E; Estrade, V; Denis, E; Yonneau, L; Mozer, P; Hadjadj, H; Hoznek, A; Traxer, O

    2014-04-01

    Since the publication of the latest recommendations of the Lithiasis Comity of the French Association of Urology (CLAFU) on the management of ureteral and renal stones, practices have evolved. This text provides an update for the treatment of kidney stones. It is especially the important advances in the field of laser-ureterorenoscopy that changed practices. Percutaneous nephrolithotomy has been enriched by technical modifications and extracorporeal shockwave lithotripsy confirmed its predominant place in the first line of treatment. For stones less than 20mm, extracorporeal lithotripsy remains the standard, but in some cases the possibility of recommending a flexible ureterorenoscopy is possible in first line. For stones more than 20mm, percutaneous nephrolithotomy is the standard treatment, but optional flexible ureteroscopy and extracorporeal lithotripsy are possible. The treatment carried out, collect the stone fragments for a morpho-constitutional analysis and achieve a metabolic evaluation is necessary, to investigate etiologic and give dietary advices to prevent recurrence.

  12. Stereotactic body radiation therapy for the treatment of early-stage minimally invasive adenocarcinoma or adenocarcnioma in situ (formerly bronchioloalveolar carcinoma: a patterns of failure analysis

    Directory of Open Access Journals (Sweden)

    Badiyan Shahed N

    2013-01-01

    Full Text Available Abstract Introduction Ongoing prospective trials exploring stereotactic body radiation therapy (SBRT for early stage non-small cell lung cancer (NSCLC often exclude minimally invasive adenocarcinoma or adenocarcnioma in situ, formerly bronchioloalveolar carcinoma (BAC, due to concerns for accurate target delineation on CT. We performed a patterns of failure analysis to compare outcomes between BAC and other NSCLC subtypes. Methods One hundred twenty patients with early stage NSCLC were treated with SBRT from 2004–2009. Pathologic confirmation of NSCLC was obtained in 97 patients. Radiotherapy was delivered according to RTOG guidelines. The log-rank test was used to compare outcomes between BAC and other NSCLC. Results Median follow-up was 29 months. The median SBRT dose was 5400 cGy. Thirteen patients had radiographically diagnosed BAC and five patients had biopsy confirmed BAC, of which two had both. The three-year local control was 100% for biopsy-proven or radiographically diagnosed BAC (n = 18 and 86% for all other NSCLC subtypes (n = 102 (p = 0.13. Likewise, no significant difference was detected between BAC and other NSCLC for 3-year regional failure (12% vs. 20%, p = 0.45, progression-free survival (57.6% vs. 53.5%, p = 0.84 or overall survival (35% vs. 47%, p = 0.66. There was a trend towards lower three-year rates of freedom from distant failure in patients with any diagnosis of BAC compared to those without (26% vs. 38%, p = 0.053. Conclusions Compared to other NSCLC subtypes, BAC appears to have similar patterns of failure and survival after treatment with SBRT, however there may be an increased risk of distant metastases with BAC. RTOG guideline-based target delineation provides encouraging local control rates for patients with BAC.

  13. Experience of percutaneous access under ultrasound guidance in renal transplant patients with allograft lithiasis

    Directory of Open Access Journals (Sweden)

    Silvano Palazzo

    2016-12-01

    : Percutaneous Nephrolithotomy (PCNL is an established safe and effective surgical treatment option for larger renal calculi in renal allografts. The ultrasound guided access to the transplanted kidney in percutaneous treatment of urolithiasis is useful and fast, minimizing patient exposure to ionizing radiation.

  14. Beam’s-eye-view dosimetrics (BEVD) guided rotational station parameter optimized radiation therapy (SPORT) planning based on reweighted total-variation minimization

    Science.gov (United States)

    Kim, Hojin; Li, Ruijiang; Lee, Rena; Xing, Lei

    2015-03-01

    Conventional VMAT optimizes aperture shapes and weights at uniformly sampled stations, which is a generalization of the concept of a control point. Recently, rotational station parameter optimized radiation therapy (SPORT) has been proposed to improve the plan quality by inserting beams to the regions that demand additional intensity modulations, thus formulating non-uniform beam sampling. This work presents a new rotational SPORT planning strategy based on reweighted total-variation (TV) minimization (min.), using beam’s-eye-view dosimetrics (BEVD) guided beam selection. The convex programming based reweighted TV min. assures the simplified fluence-map, which facilitates single-aperture selection at each station for single-arc delivery. For the rotational arc treatment planning and non-uniform beam angle setting, the mathematical model needs to be modified by additional penalty term describing the fluence-map similarity and by determination of appropriate angular weighting factors. The proposed algorithm with additional penalty term is capable of achieving more efficient and deliverable plans adaptive to the conventional VMAT and SPORT planning schemes by reducing the dose delivery time about 5 to 10 s in three clinical cases (one prostate and two head-and-neck (HN) cases with a single and multiple targets). The BEVD guided beam selection provides effective and yet easy calculating methodology to select angles for denser, non-uniform angular sampling in SPORT planning. Our BEVD guided SPORT treatment schemes improve the dose sparing to femoral heads in the prostate and brainstem, parotid glands and oral cavity in the two HN cases, where the mean dose reduction of those organs ranges from 0.5 to 2.5 Gy. Also, it increases the conformation number assessing the dose conformity to the target from 0.84, 0.75 and 0.74 to 0.86, 0.79 and 0.80 in the prostate and two HN cases, while preserving the delivery efficiency, relative to conventional single-arc VMAT plans.

  15. Dose optimization with first-order total-variation minimization for dense angularly sampled and sparse intensity modulated radiation therapy (DASSIM-RT).

    Science.gov (United States)

    Kim, Hojin; Li, Ruijiang; Lee, Rena; Goldstein, Thomas; Boyd, Stephen; Candes, Emmanuel; Xing, Lei

    2012-07-01

    A new treatment scheme coined as dense angularly sampled and sparse intensity modulated radiation therapy (DASSIM-RT) has recently been proposed to bridge the gap between IMRT and VMAT. By increasing the angular sampling of radiation beams while eliminating dispensable segments of the incident fields, DASSIM-RT is capable of providing improved conformity in dose distributions while maintaining high delivery efficiency. The fact that DASSIM-RT utilizes a large number of incident beams represents a major computational challenge for the clinical applications of this powerful treatment scheme. The purpose of this work is to provide a practical solution to the DASSIM-RT inverse planning problem. The inverse planning problem is formulated as a fluence-map optimization problem with total-variation (TV) minimization. A newly released L1-solver, template for first-order conic solver (TFOCS), was adopted in this work. TFOCS achieves faster convergence with less memory usage as compared with conventional quadratic programming (QP) for the TV form through the effective use of conic forms, dual-variable updates, and optimal first-order approaches. As such, it is tailored to specifically address the computational challenges of large-scale optimization in DASSIM-RT inverse planning. Two clinical cases (a prostate and a head and neck case) are used to evaluate the effectiveness and efficiency of the proposed planning technique. DASSIM-RT plans with 15 and 30 beams are compared with conventional IMRT plans with 7 beams in terms of plan quality and delivery efficiency, which are quantified by conformation number (CN), the total number of segments and modulation index, respectively. For optimization efficiency, the QP-based approach was compared with the proposed algorithm for the DASSIM-RT plans with 15 beams for both cases. Plan quality improves with an increasing number of incident beams, while the total number of segments is maintained to be about the same in both cases. For the

  16. 胰腺疾患误诊为泌尿系结石5例分析%Pancreatic disorders misdiagnosed as urinary lithiasis (5 cases report)

    Institute of Scientific and Technical Information of China (English)

    李涛; 吴翔; 张弛; 吴进锋; 余澄波; 尚华辉

    2015-01-01

    Objective To analyze the causes of misdiagnosis of pancreatic disorders as urinary lithiasis.Methods The clinical data of 5 cases of pancreatic disorders misdiagnosed as urinary lithiasis in our hospital in the recent decade were reviewed.Results 4 cases of acute pancreatitis with left lumbago were misdiagnosed as lithiasis of left upper urinary tract, and a case of pancreatic duct stone was misdiagnosed as right renal stone. All the 5 cases had some abdominal symptoms such as pain in the upper abdomen, nausea, vomiting and abdominal distension. The misdiagnoses lasted 2-4 days when the correct diagnoses were made. 3 cases survived, and 2 cases of severe pancreatitis died eventually.Conclusions For a patient previously diagnosed urinary lithiasis because of lumbago or acute renal failure, the diagnosis of acute pancreatitis should be also suspected if there are inexplainable abdominal symptoms, especially when the pain rises from the upper abdomen. Intravenous urography should be routinely carried out for the patients with urinary lithiasis who is ready to receive extracorporeal shockwave lithotripsy or surgical treatment.%目的:分析胰腺疾患误诊为泌尿系结石的常见原因。方法:对本院近10年收治的首诊误诊为泌尿系结石的5例胰腺疾病患者的临床资料进行回顾性分析。结果:4例急性胰腺炎误诊为左上尿路结石,1例胰管结石误诊为右肾结石,均有明显的腰痛,伴有不同程度的上腹痛、恶心、呕吐、腹胀等腹部症状,误诊时间2~4天,3例治愈,2例重症胰腺炎死亡。结论:对临床疑诊为泌尿系结石的腰痛或急性肾功能衰竭患者,如伴有难以解释的腹部症状,尤其是以上腹痛起病者,要考虑到急性胰腺炎等胰腺疾患的可能性;对泌尿系结石患者行ESWL或手术治疗之前应常规进行IVU检查。

  17. QCD-resummation and non-minimal flavour-violation for supersymmetric particle production at hadron colliders; Resommation des corrections radiatives QCD et violation de la saveur non-minimale pour la production de particules supersymetriques aupres des collisionneurs hadroniques

    Energy Technology Data Exchange (ETDEWEB)

    Fuks, B

    2007-06-15

    Cross sections for supersymmetric particles production at hadron colliders have been extensively studied in the past at leading order and also at next-to-leading order of perturbative QCD. The radiative corrections include large logarithms which have to be re-summed to all orders in the strong coupling constant in order to get reliable perturbative results. In this work, we perform a first and extensive study of the resummation effects for supersymmetric particle pair production at hadron colliders. We focus on Drell-Yan like slepton-pair and slepton-sneutrino associated production in minimal supergravity and gauge-mediated supersymmetry-breaking scenarios, and present accurate transverse-momentum and invariant-mass distributions, as well as total cross sections. In non-minimal supersymmetric models, novel effects of flavour violation may occur. In this case, the flavour structure in the squark sector cannot be directly deduced from the trilinear Yukawa couplings of the fermion and Higgs supermultiplets. We perform a precise numerical analysis of the experimentally allowed parameter space in the case of minimal supergravity scenarios with non-minimal flavour violation, looking for regions allowed by low-energy, electroweak precision, and cosmological data. Leading order cross sections for the production of squarks and gauginos at hadron colliders are implemented in a flexible computer program, allowing us to study in detail the dependence of these cross sections on flavour violation. (author)

  18. Optimizing the radiation therapy dose prescription for pediatric medulloblastoma: Minimizing the life years lost attributable to failure to control the disease and late complication risk

    DEFF Research Database (Denmark)

    Brodin, N. Patrik; Vogelius, Ivan R.; Bjork-Eriksson, Thomas

    2014-01-01

    Background. A mathematical framework is presented for simultaneously quantifying and evaluating the trade-off between tumor control and late complications for risk-based radiation therapy (RT) decision-support. To demonstrate this, we estimate life years lost (LYL) attributable to tumor recurrence......, late cardiac toxicity and secondary cancers for standard-risk pediatric medulloblastoma (MB) patients and compare the effect of dose re-distribution on a common scale. Methods. Total LYL were derived, based on the LYL attributable to radiation-induced late complications and the LYL from not controlling...... in this context, the gain is small compared to estimated uncertainty, this study demonstrates a framework for all-cause mortality risk estimation, rather than evaluates direct clinical applicability of risk-adapted strategies....

  19. Minimal cosmography

    CERN Document Server

    Piazza, Federico

    2015-01-01

    The minimal requirement for cosmography - a nondynamical description of the universe - is a prescription for calculating null geodesics, and timelike geodesics as a function of their proper time. In this paper, we consider the most general linear connection compatible with homogeneity and isotropy, but not necessarily with a metric. A light-cone structure is assigned by choosing a set of geodesics representing light rays. This defines a "scale factor" and a local notion of distance, as that travelled by light in a given proper time interval. We find that the velocities and relativistic energies of free-falling bodies decrease in time as a consequence of cosmic expansion, but at a rate that can be different than that dictated by the usual metric framework. By extrapolating this behavior to photons redshift, we find that the latter is in principle independent of the "scale factor". Interestingly, redshift-distance relations and other standard geometric observables are modified in this extended framework, in a w...

  20. Minimal cosmography

    Science.gov (United States)

    Piazza, Federico; Schücker, Thomas

    2016-04-01

    The minimal requirement for cosmography—a non-dynamical description of the universe—is a prescription for calculating null geodesics, and time-like geodesics as a function of their proper time. In this paper, we consider the most general linear connection compatible with homogeneity and isotropy, but not necessarily with a metric. A light-cone structure is assigned by choosing a set of geodesics representing light rays. This defines a "scale factor" and a local notion of distance, as that travelled by light in a given proper time interval. We find that the velocities and relativistic energies of free-falling bodies decrease in time as a consequence of cosmic expansion, but at a rate that can be different than that dictated by the usual metric framework. By extrapolating this behavior to photons' redshift, we find that the latter is in principle independent of the "scale factor". Interestingly, redshift-distance relations and other standard geometric observables are modified in this extended framework, in a way that could be experimentally tested. An extremely tight constraint on the model, however, is represented by the blackbody-ness of the cosmic microwave background. Finally, as a check, we also consider the effects of a non-metric connection in a different set-up, namely, that of a static, spherically symmetric spacetime.

  1. Evaluation of the effects of gamma radiation on physicochemical characteristics of kiwi (Actinidia deliciosa) cv. Hayward minimally processed; Avaliacao dos efeitos da radiacao gama nas caracteristicas fisico-quimicas de kiwi (Actinidia deliciosa) cv. Hayward minimamente processado

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Ana Claudia Sampaio

    2011-07-01

    The search for a healthy life has led consumers to rethink their eating habits, consuming fruits and vegetables in place of manufactured products, therefore, the demand for minimally processed products has evolved rapidly. The kiwi fruit (Actinidia deliciosa) has high nutritional value, being rich in C vitamin especially, which has wide acceptance in consumer markets. Thus, along with papaya, passion fruit and pineapple, kiwi can be considered as an additional feature of C vitamin in the diet, or as a substitute for traditional citrus. The aim of this study was to assess the effects of gamma radiation on physical and chemical characteristics of kiwis minimally processed and stored under refrigeration, since this technology increases the shelf life of fruits and vegetables. The Kiwis was stripped, processed and cut into slices, stored in polyethylene bags of 10 cm squared and irradiated at doses of 0 (control), 1 and 2 kGy. A source of {sup 60}Co Gammacell 220, dose rate of 0.429 kGy/hour, in which each treatment had 5 replicates with 15 slices of kiwifruit per replicate. After irradiation the samples were stored in a climatic chamber at 6 degree C (near the temperature of commercial refrigerators). The following criteria were physical chemical analysis: pH, color, chlorophyll content, loss of weight, moisture, acidity and Brix. The analysis were done on 1{sup st}, 7{sup th} and 14{sup th} days after irradiation. The results indicated that gamma radiation did not induce deleterious changes in the physicochemical properties of the kiwi may be used for preservation of minimally processed kiwifruit. (author)

  2. Minimally Invasive Dentistry

    Science.gov (United States)

    ... to your desktop! more... What Is Minimally Invasive Dentistry? Article Chapters What Is Minimally Invasive Dentistry? Minimally ... techniques. Reviewed: January 2012 Related Articles: Minimally Invasive Dentistry Minimally Invasive Veneers Dramatically Change Smiles What Patients ...

  3. Flexible delivery of Er:YAG radiation at 2.94 µm with negative curvature silica glass fibers: a new solution for minimally invasive surgical procedures.

    Science.gov (United States)

    Urich, A; Maier, R R J; Yu, Fei; Knight, J C; Hand, D P; Shephard, J D

    2013-02-01

    We present the delivery of high energy microsecond pulses through a hollow-core negative-curvature fiber at 2.94 µm. The energy densities delivered far exceed those required for biological tissue manipulation and are of the order of 2300 J/cm(2). Tissue ablation was demonstrated on hard and soft tissue in dry and aqueous conditions with no detrimental effects to the fiber or catastrophic damage to the end facets. The energy is guided in a well confined single mode allowing for a small and controllable focused spot delivered flexibly to the point of operation. Hence, a mechanically and chemically robust alternative to the existing Er:YAG delivery systems is proposed which paves the way for new routes for minimally invasive surgical laser procedures.

  4. Optimizing bone surveys performed for suspected non-accidental trauma with attention to maximizing diagnostic yield while minimizing radiation exposure: utility of pelvic and lateral radiographs

    Energy Technology Data Exchange (ETDEWEB)

    Jha, Priyanka; Stein-Wexler, Rebecca; Seibert, Anthony; Wootton-Gorges, Sandra L. [University of California Davis Medical Center, Department of Radiology, Sacramento, CA (United States); Coulter, Kevin [University of California Davis Medical Center, Department of Pediatrics, Sacramento, CA (United States); Li, Chin-Shang [University of California Davis Medical Center, Division of Biostatistics, Department of Public Health Sciences, Sacramento, CA (United States)

    2013-06-15

    Skeletal surveys for non-accidental trauma (NAT) include lateral spinal and pelvic views, which have a significant radiation dose. To determine whether pelvic and lateral spinal radiographs should routinely be performed during initial bone surveys for suspected NAT. The radiology database was queried for the period May 2005 to May 2011 using CPT codes for skeletal surveys for suspected NAT. Studies performed for skeletal dysplasia and follow-up surveys were excluded. Initial skeletal surveys were reviewed to identify fractures present, including those identified only on lateral spinal and/or pelvic radiographs. Clinical information and MR imaging was reviewed for the single patient with vertebral compression deformities. Of the 530 children, 223 (42.1%) had rib and extremity fractures suspicious for NAT. No fractures were identified solely on pelvic radiographs. Only one child (<0.2%) had vertebral compression deformities identified on a lateral spinal radiograph. This infant had rib and extremity fractures and was clinically paraplegic. MR imaging confirmed the vertebral body fractures. Since no fractures were identified solely on pelvic radiographs and on lateral spinal radiographs in children without evidence of NAT, nor in nearly all with evidence of NAT, inclusion of these views in the initial evaluation of children for suspected NAT may not be warranted. (orig.)

  5. Minimizing the background radiation in the new neutron time-of-flight facility at CERN FLUKA Monte Carlo simulations for the optimization of the n_TOF second experimental line

    CERN Document Server

    Bergström, Ida; Elfgren, Erik

    2013-06-11

    At the particle physics laboratory CERN in Geneva, Switzerland, the Neutron Time-of-Flight facility has recently started the construction of a second experimental line. The new neutron beam line will unavoidably induce radiation in both the experimental area and in nearby accessible areas. Computer simulations for the minimization of the background were carried out using the FLUKA Monte Carlo simulation package. The background radiation in the new experimental area needs to be kept to a minimum during measurements. This was studied with focus on the contributions from backscattering in the beam dump. The beam dump was originally designed for shielding the outside area using a block of iron covered in concrete. However, the backscattering was never studied in detail. In this thesis, the fluences (i.e. the flux integrated over time) of neutrons and photons were studied in the experimental area while the beam dump design was modified. An optimized design was obtained by stopping the fast neutrons in a high Z mat...

  6. Evaluating the design of an earth radiation budget instrument with system simulations. Part 2: Minimization of instantaneous sampling errors for CERES-I

    Science.gov (United States)

    Stowe, Larry; Hucek, Richard; Ardanuy, Philip; Joyce, Robert

    1994-01-01

    Much of the new record of broadband earth radiation budget satellite measurements to be obtained during the late 1990s and early twenty-first century will come from the dual-radiometer Clouds and Earth's Radiant Energy System Instrument (CERES-I) flown aboard sun-synchronous polar orbiters. Simulation studies conducted in this work for an early afternoon satellite orbit indicate that spatial root-mean-square (rms) sampling errors of instantaneous CERES-I shortwave flux estimates will range from about 8.5 to 14.0 W/m on a 2.5 deg latitude and longitude grid resolution. Rms errors in longwave flux estimates are only about 20% as large and range from 1.5 to 3.5 W/sq m. These results are based on an optimal cross-track scanner design that includes 50% footprint overlap to eliminate gaps in the top-of-the-atmosphere coverage, and a 'smallest' footprint size to increase the ratio in the number of observations lying within to the number of observations lying on grid area boundaries. Total instantaneous measurement error also depends on the variability of anisotropic reflectance and emission patterns and on retrieval methods used to generate target area fluxes. Three retrieval procedures from both CERES-I scanners (cross-track and rotating azimuth plane) are used. (1) The baseline Earth Radiaton Budget Experiment (ERBE) procedure, which assumes that errors due to the use of mean angular dependence models (ADMs) in the radiance-to-flux inversion process nearly cancel when averaged over grid areas. (2) To estimate N, instantaneous ADMs are estimated from the multiangular, collocated observations of the two scanners. These observed models replace the mean models in computation of satellite flux estimates. (3) The scene flux approach, conducts separate target-area retrievals for each ERBE scene category and combines their results using area weighting by scene type. The ERBE retrieval performs best when the simulated radiance field departs from the ERBE mean models by less than

  7. Evaluating the design of an earth radiation budget instrument with system simulations. Part 2: Minimization of instantaneous sampling errors for CERES-I

    Science.gov (United States)

    Stowe, Larry; Hucek, Richard; Ardanuy, Philip; Joyce, Robert

    1994-01-01

    Much of the new record of broadband earth radiation budget satellite measurements to be obtained during the late 1990s and early twenty-first century will come from the dual-radiometer Clouds and Earth's Radiant Energy System Instrument (CERES-I) flown aboard sun-synchronous polar orbiters. Simulation studies conducted in this work for an early afternoon satellite orbit indicate that spatial root-mean-square (rms) sampling errors of instantaneous CERES-I shortwave flux estimates will range from about 8.5 to 14.0 W/m on a 2.5 deg latitude and longitude grid resolution. Rms errors in longwave flux estimates are only about 20% as large and range from 1.5 to 3.5 W/sq m. These results are based on an optimal cross-track scanner design that includes 50% footprint overlap to eliminate gaps in the top-of-the-atmosphere coverage, and a 'smallest' footprint size to increase the ratio in the number of observations lying within to the number of observations lying on grid area boundaries. Total instantaneous measurement error also depends on the variability of anisotropic reflectance and emission patterns and on retrieval methods used to generate target area fluxes. Three retrieval procedures from both CERES-I scanners (cross-track and rotating azimuth plane) are used. (1) The baseline Earth Radiaton Budget Experiment (ERBE) procedure, which assumes that errors due to the use of mean angular dependence models (ADMs) in the radiance-to-flux inversion process nearly cancel when averaged over grid areas. (2) To estimate N, instantaneous ADMs are estimated from the multiangular, collocated observations of the two scanners. These observed models replace the mean models in computation of satellite flux estimates. (3) The scene flux approach, conducts separate target-area retrievals for each ERBE scene category and combines their results using area weighting by scene type. The ERBE retrieval performs best when the simulated radiance field departs from the ERBE mean models by less than

  8. Randomized comparison of operator radiation exposure comparing transradial and transfemoral approach for percutaneous coronary procedures: rationale and design of the minimizing adverse haemorrhagic events by TRansradial access site and systemic implementation of angioX – RAdiation Dose study (RAD-MATRIX)

    Energy Technology Data Exchange (ETDEWEB)

    Sciahbasi, Alessandro, E-mail: alessandro.sciahbasi@fastwebnet.it [Interventional Cardiology, Sandro Pertini Hospital – ASL RMB, Rome (Italy); Calabrò, Paolo [Division of Cardiology - Department of Cardio-Thoracic Sciences - Second University of Naples (Italy); Sarandrea, Alessandro [HSE Management, Rome (Italy); Rigattieri, Stefano [Interventional Cardiology, Sandro Pertini Hospital – ASL RMB, Rome (Italy); Tomassini, Francesco [Department of Cardiology, Infermi Hospital, Rivoli (Italy); Sardella, Gennaro [La Sapienza University, Rome (Italy); Zavalloni, Dennis [UO Emodinamica e Cardiologia Invasiva, IRCCS, Istituto Clinico Humanitas, Rozzano (Italy); Cortese, Bernardo [Interventional Cardiology, Fatebenefratelli Hospital, Milan (Italy); Limbruno, Ugo [Cardiology Unit, Misericordia Hospital, Grosseto (Italy); Tebaldi, Matteo [Cardiology Department, University of Ferrara, Department of Cardiology (Italy); Gagnor, Andrea [Department of Cardiology, Infermi Hospital, Rivoli (Italy); Rubartelli, Paolo [Villa Scassi Hospital, Genova (Italy); Zingarelli, Antonio [San Martino Hospital, Genova (Italy); Valgimigli, Marco [Thoraxcenter, Rotterdam (Netherlands)

    2014-06-15

    Background: Radiation absorbed by interventional cardiologists is a frequently under-evaluated important issue. Aim is to compare radiation dose absorbed by interventional cardiologists during percutaneous coronary procedures for acute coronary syndromes comparing transradial and transfemoral access. Methods: The randomized multicentre MATRIX (Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX) trial has been designed to compare the clinical outcome of patients with acute coronary syndromes treated invasively according to the access site (transfemoral vs. transradial) and to the anticoagulant therapy (bivalirudin vs. heparin). Selected experienced interventional cardiologists involved in this study have been equipped with dedicated thermoluminescent dosimeters to evaluate the radiation dose absorbed during transfemoral or right transradial or left transradial access. For each access we evaluate the radiation dose absorbed at wrist, at thorax and at eye level. Consequently the operator is equipped with three sets (transfemoral, right transradial or left transradial access) of three different dosimeters (wrist, thorax and eye dosimeter). Primary end-point of the study is the procedural radiation dose absorbed by operators at thorax. An important secondary end-point is the procedural radiation dose absorbed by operators comparing the right or left radial approach. Patient randomization is performed according to the MATRIX protocol for the femoral or radial approach. A further randomization for the radial approach is performed to compare right and left transradial access. Conclusions: The RAD-MATRIX study will probably consent to clarify the radiation issue for interventional cardiologist comparing transradial and transfemoral access in the setting of acute coronary syndromes.

  9. Evaluation of the effects of gamma radiation in minimally processed vegetables of Brassica oleracea species; Avaliacao dos efeitos da radiacao gama em vegetais da especie Brassica oleracea minimamente processados

    Energy Technology Data Exchange (ETDEWEB)

    Nunes, Thaise Cristine Fernandes

    2009-07-01

    The consumption of collard greens (Brassica oleracea cv. acephala) and broccoli (Brassica oleracea L. var. italica) has been inversely associated with morbidity and mortality caused by degenerative diseases. These species are highly consumed in Brazil, which enables its use as minimally processed (MP). The growing worldwide concern with the storage, nutritional quality and microbiological safety of food has led to many studies aimed at microbiological analysis, vitamin and shelf life. To improve the quality of these products, radiation processing can be effective in maintaining the quality of the product, rather compromising their nutritional values and sensory. The aim of this study was to evaluate the effectiveness of gamma radiation from {sup 60}Co at doses of 0, 1.0 and 1.5 kGy on the reduction of microbiota in these plants, and analyze their nutritional and sensory characteristics. The methodology used in this study was microbiological analysis, colorimetric analysis, analysis of phenolic compounds, antioxidant analysis and sensory analysis. The microbiological analysis showed a decrease in the development of populations of aerobic microorganisms, psychotropic and yeast and mold with increasing doses of radiation. The sensory analysis showed no significant difference between different times of cooking analyzed. The analysis of phenolic compounds, significant differences between the samples, suggesting that with increasing dose of irradiation was an increase in the amount of phenolic compounds found in broccoli and collard greens MP. It can be observed that the sample of control collard greens showed high antioxidant activity and for the samples treated by irradiation was a decrease of percentage. In contrast the samples of broccoli show an increase in the rate of scavenging DPPH with increase of the dose of radiation. The colorimetric analysis revealed that for samples of MP collard greens and broccoli foil of no significant differences, but for samples of

  10. Minimal Mirror Twin Higgs

    CERN Document Server

    Barbieri, Riccardo; Harigaya, Keisuke

    2016-01-01

    In a Mirror Twin World with a maximally symmetric Higgs sector the little hierarchy of the Standard Model can be significantly mitigated, perhaps displacing the cutoff scale above the LHC reach. We show that consistency with observations requires that the Z2 parity exchanging the Standard Model with its mirror be broken in the Yukawa couplings. A minimal such effective field theory, with this sole Z2 breaking, can generate the Z2 breaking in the Higgs sector necessary for the Twin Higgs mechanism, and has constrained and correlated signals in invisible Higgs decays, direct Dark Matter Detection and Dark Radiation, all within reach of foreseen experiments. For dark matter, both mirror neutrons and a variety of self-interacting mirror atoms are considered. Neutrino mass signals and the effects of a possible additional Z2 breaking from the vacuum expectation values of B-L breaking fields are also discussed.

  11. Effect of gamma radiation in the conservation of minimally processed cassava-parsley (Arracacia xanthorrhiza Bancroft) packed under vacuous;Efeito da radiacao gama na conservacao da mandioquinha-salsa (Arracacia xanthorrhiza Bancroft) minimamente processada e embalada a vacuo

    Energy Technology Data Exchange (ETDEWEB)

    Iemma, Juliana

    2001-07-01

    In the third millennium, when the main words are globalization, world net of computers, genetic code and efficiency, deep transformations have been incorporated to human behavior. Among such transformations it may be pointed out, matching with the objectives of this study, the modem consumer's profile. The consumers have quickly become more and more conscious and demanding regarding to the quality of the available products in the market. In that sense, the consumer's concern about the natural and healthy appearance, as well as the preservation of the nutritious content of the foods, have been a constant sign of alert for producers and suppliers. Besides, the timeless for domestic preparation of foods have imposed the use of minimally processed as an incontestable reality. A barrier for the production of minimally processed foods is imposed by the degree of perishability of certain products, such as the cassava-parsley. This vegetable is a source of energy, calcium, phosphorus and niacin, and important in the alimentary diet of children, seniors and convalescents. Post harvest treatments try to turn foods less perishable and also conserve as much as possible their original appearance. Among these post harvest treatments for food conservation it may be stood out the irradiation, which is the focus of this study. The objective of this study was to examine the viability of including the cassava parsley in the list of the minimally processed foods. Fresh cassavas were minimally processed and packed under vacuous. Samples were divided for three treatments: control and irradiation with the doses 2.0 and 4.0 kGy. After irradiation the samples were stored under refrigeration temperature (8 deg C) during 28 days. Physical-chemical and microbiological analyzes were carried out at each 7 days of the period of storage, and sensorial analysis were carried out in the 1st, 7th and 14th days of storage. The experimental design was in factorial scheme with two factors

  12. Litiasis renal: Modificaciones bioquímicas durante el seguimiento Renal lithiasis: Biochemical changes in the follow-up

    Directory of Open Access Journals (Sweden)

    Francisco R. Spivacow

    2006-06-01

    Full Text Available Con el objeto de evaluar si se producen modificaciones bioquímicas durante el seguimiento de pacientes nefrolitiásicos, se estudiaron 237 pacientes (115 mujeres y 122 hombres con una edad promedio de 39 ± 8 y 42 ± 7 años respectivamente controlados durante 23.7 ± 19.3 meses. A todos se les realizó un estudio metabólico de litiasis renal inicial y como mínimo uno o más posteriormente con las mismas características que el basal. No fueron incluidos pacientes con los diagnósticos de riñón en esponja, acidosis renotubular, hiperparatiroidismo primario, malformaciones renales o infecciones urinarias. Del total de pacientes, 139 (Grupo I presentaron en el seguimiento una modificación metabólica no evidenciada en el estudio inicial, mientras que 98 (Grupo II no. El tiempo de seguimiento de los primeros, no fue significativamente diferente de aquellos que no modificaron el diagnóstico basal. Las alteraciones bioquímicas agregadas más frecuentes fueron, hipocitraturia en el 43.1%, hipercalciuria idiopática en 20.8% y alteraciones del ácido úrico en 16.5%. De 110 pacientes seguidos más de 3 años, 37 (33% recurrieron. De éstos, 25 (23% modificaron el diagnóstico metabólico basal vs. 12 (11% que mantuvieron el mismo diagnóstico (p With the aim of assessing if biochemical changes occur in the follow up of patients with renal lithiasis, 237 patients were studied (115 women and 122 men, mean age 39 ± 8 and 42 ± 7 years, respectively and controlled during 27.3 ± 19.3 months. All of them had previously undergone metabolic evaluations at baseline and one or more than one control studies afterwards. Patients with a diagnosis of sponge kidney, renal tubular acidosis, primary hyperparathyroidism, anatomical malformations of the urinary tract, or urinary infections were not included. Two populations were identified: those who presented changes in the baseline diagnosis (139 patients, Group I and those who presented no changes (98

  13. Tratamento laparoscópico de coledocolitíase Laparoscopic treatment of common bile duct lithiasis

    Directory of Open Access Journals (Sweden)

    Marcel Autran C. MACHADO

    2000-07-01

    Full Text Available Paciente com história de 18 meses de emagrecimento e icterícia foi encaminhado ao Serviço de Cirurgia Abdominal do Hospital do Câncer, São Paulo, SP., com hipótese diagnóstica de câncer de cabeça de pâncreas. Exames laboratoriais mostraram elevação de bilirrubinas e de enzimas canaliculares. Ultra-sonografia abdominal revelou dilatação de via biliar intra e extra-hepática. Tomografia computadorizada mostrou árvore biliar dilatada com presença de cálculo de cerca de 3 cm em colédoco distal. O paciente foi submetido a colecistectomia com coledocotomia, retirada do cálculo e anastomose colédoco-duodenal por laparoscopia. Evoluiu sem intercorrências, recebendo alta no sexto dia de pós-operatório. Conclui-se que o tratamento laparoscópico da coledocolitíase é factível em alguns pacientes, especialmente naqueles com dilatação de via biliar. A retirada de cálculos deve ser seguida de procedimento de drenagem da via biliar com dreno de Kehr. Em alguns pacientes com colédoco cronicamente dilatado, como o do presente caso, a anastomose colédoco-duodenal é o procedimento de escolha.With the advances of videolaparoscopic surgery, this approach had become the treatment of choice for cholelithiasis. However, about 5% to 10% may present common bile duct lithiasis. Most surgeons have still difficulties to deal with this situation and do prefer resolve with open surgery or with further endoscopic approach. We present a case of a 60-year-old man, with 18 months history of right upper quadrant pain, weight loss and jaundice. He was referred with diagnostic of pancreatic cancer. Laboratory investigation showed increased bilirrubin (10 mg/dL, alkaline phosphatase and GGT. Abdominal ultrasound showed atrophic gallbladder with dilated intra and extrahepatic biliary tree. Computerized tomography scan disclosed enlarged biliary tree with 3 cm stone in the distal common bile duct. The patient underwent a laparoscopic cholecystectomy

  14. [Epidemiology of urinary lithiasis].

    Science.gov (United States)

    Joual, A; Rais, H; Rabii, R; el Mrini, M; Benjelloun, S

    1997-01-01

    The objective of this study was to analyse the epidemiological profile of urinary stones based on one thousand cases observed in our institution over a 10-year period. The mean age of the patients was 45 years and two-thirds of patients were males. The kidney was the commonest site of stones, in 57.8% of cases. The stone was radiopaque in 86.4% of cases and was a staghorn calculus in 12.2% of cases. An associated renal malformation was observed in 10.4% of cases. Urinary stones is therefore a common disease, essentially observed in a young population and characterized by recurrence. It therefore constitutes a public health problem and prevention consists of detecting recurrences and treating stone-inducing factors.

  15. El ácido linoleico conjugado disminuye la hipercolesterolemia pero aumenta el riesgo de litiasis biliar Conjugated linoleic acid lowers hypercholesterolemia but increases the risk for biliary lithiasis

    Directory of Open Access Journals (Sweden)

    V. Navarro

    2005-06-01

    ruminants that have their double bonds in a conjugated position. The aim of the present work was to study the effects of a CLA isomer, trans-10,cis-12, on cholesterolemia and biliary lithiasis risk in an animal model of diet-induced hypercholesterolemia. For that, two groups of hamsters were fed with a hypercholesterolemic diet supplemented with 0.5% linoleic acid or with the trans-10,cis-12 CLA isomer, respectively. Daily food intake and weight were determined and, 6 weeks later, serum and bile samples were obtained, and livers and spleens were dissected and weighted. Cholesterolemia, hepatic and splenic cholesterol content, and biliary cholesterol phosnolipid and bileacid concentrations were determined; Biliary Lithogenic Index was calculated, and presence of gallstones was assessed. CLA did not modify energetic intake or final body weight, spleen size or spleen cholesterol content, but it did significantly reduce total serum cholesterol (-18% at the expense of c-LDL (-66%, and it also significantly reduced hepatic content of free cholesterol (-26%, without changes in esterified cholesterol. Besides, CLA produced a 32% increase in biliary cholesterol concentration, a 28% increase in Lithogenic Index, and a higher incidence of biliary lithiasis. Therefore, the present study shows that the CLA trans-10,cis-12 isomer is hypercholesterolemic since it increases, at least in part, cholesterol secretion to the bile. As a consequence, this effect increases the risk for biliary lithiasis.

  16. Action of gamma radiation in the physico-chemical and sensorial characteristics of minimally processed cassava (Manihot esculenta CRANTZ);Acao da radiacao gama nas caracteristicas fisico-quimicas e sensoriais da mandioca (Manihot esculenta CRANTZ) minimamente processada

    Energy Technology Data Exchange (ETDEWEB)

    Simioni, Karime Raya

    2001-07-01

    Nowadays irradiation has been the most studied method of food conservation. The publication of thousand of papers, not just scientific but also technological, economical and social, have proved the technical validity of the irradiation method and showed the ways of how to introduce it in commercial facilities in ali countries of the modem world. Cassava is cultivated almost ali over the world and it is considered one of the most important nutritious sources of calories in human diet. Cassava is a viable food against starving in several poor areas of the world because it is an extremely resistant culture and may reach satisfactory economical yield. Cassava is a quite perishable root, characterized by fast post harvest deterioration. Because of the lack of researches about the effects of radiations in this root, the objective of the present work was to examine the gamma radiation coming from {sup 60}Cobalt as a treatment to prolong the shelflife of the root after harvesting, aiming to increase its period of commercialization and to conserve its sensorial characteristics for a longer period. Samples were washed, peeled, cleaned and diced cassava roots packed in polyethylene bags. The treatments were: control; freezing and storage at 18 deg C for 21 days; and irradiation with the doses of 8 and 10 kGy. The control and the irradiated samples were stored under ambient temperature during 21 days. All samples were analyzed at each 7 days for alterations in the physicochemical and sensorial characteristics. The samples were analyzed for pH, acidity, weight, humidity, texture and color. The irradiation did not affect the chemical characteristics of the cassava. Neither the pH nor the acidity, the most relevant variables to verify deterioration in cassava, presented significant alterations during the period of storage. Comparing the irradiated treatments, the dose of 8 kGy was that less affected the physic-chemical characteristics of the cassava and scored the highest notes

  17. Production of the PET bone agent (18)F-fluoride ion, simultaneously with (18)F-FDG by a single run of the medical cyclotron with minimal radiation exposure- a novel technique.

    Science.gov (United States)

    Kumar, Rajeev; Sonkawade, Rajendra G; Tripathi, Madhavi; Sharma, Punit; Gupta, Priyanka; Kumar, Praveen; Pandey, Anil K; Bal, Chandrasekhar; Damle, Nishikant Avinash; Bandopadhayaya, Gurupad

    2014-01-01

    Our aim was to establish an easy and convenient procedure for the preparation of fluorine-18-sodium fluoride ((18)F-NaF) for bone positron emission tomography (PET) during routine (18)F-FDG production using the Explora FDG4 radiochemistry module (EFRM) by single run of Cyclotron with negligible radiation exposure. We compared three techniques for (18)F-NaF production during routine PET radiochemistry at our setup. In one method we used synthesis module and in other two methods we did not. In the first and third method, F-18 was directly extracted from the V-vial and in the second method, (18)F-NaF was extracted by post processing from the EFRM. In the first method, F-18 was extracted directly from V-vial manually by opening the V-vial cap. In the second method, Explora FDG-4 Module was used. First, F-18 was transferred from the V-vial. Then, after post processing in EFRM, pure F-18 was obtained in the product vial. In the third method, pure F-18 was obtained in the product vial with the help of a mechanical robotic arm. The above were followed by routine quality control of (18)F-NaF produced by each method. Results of quality control of the (18)F-NaF obtained by all three methods satisfied all parameters prescribed by the United States Pharmacopeia (USP) and the British Pharmacopeia (BP) including biological, physical and chemical specifications. The radiochemical purity was 98.5±1.5% with Rf 0.006. The level of Kryptofix-222 (K222) in (18)F-NaF was within the prescribed limit. Mean pH of (18)F-NaF was 6.0±1.5. The exposure rate around the hot cell was negligible. In conclusion, from the results it was obvious that by our method number three (18)F-NaF was directly obtained from the V-vial using mechanical robotic arms. This method was the most appropriate with minimized radiation exposure to the handling Radiochemist and was also saving time as compared to the other two methods.

  18. [Management of adult's renal and ureteral stones. Update of the Lithiasis Committee of the French Association of Urology (CLAFU). General considerations].

    Science.gov (United States)

    Chabannes, É; Bensalah, K; Carpentier, X; Bringer, J-P; Conort, P; Denis, É; Dore, B; Estrade, V; Gautier, J-R; Hadjadj, H; Hubert, J; Hoznek, A; Lechevallier, É; Meria, P; Mozer, P; Saussine, C; Yonneau, L; Traxer, O

    2013-12-01

    The Lithiasis Committee of the French Association of Urology (CLAFU) aimed to update the current knowledge about urolithiasis. This update will be divided into four parts: 1) general considerations; 2) the management of ureteral stones; 3) the management of kidney stones; 4) metabolic assessment and medical treatment of urolithiasis. Recent technicals advances helped the urologists to improve stones management: new extracorporeal shockwave lithotripsy (ESWL) devices, new flexible ureterorenoscopes, development of laser fragmentation. ESWL, semi-rigid and flexible ureteroscopy and the percutaneous nephrolithotomy (PCNL) remain currently the main therapeutic options. The first part of this update deals with the description and classification of stones, preoperative assessment, post-operative management and clinical follow-up. Main criteria of therapeutic choices are stone location, stone composition and stone size. Stone composition is assessed with infrared spectrophotometry analysis and its hardness is correlated with U.H. density on CT scan assessment. Preoperative assessment consists in urinary cytobacteriological examine, urinary PH, blood creatininemia, hemostasis. Low-dose CT scan is recommended before urological treatment. The result of the treatment must be done 1 or 3 months later with plain abdominal film and ultrasonography. Medical management of urolithiasis will be based on stone composition, metabolic and nutritional evaluation. Treatment success is definited by absence of residual fragments. Annual follow-up is recommended and based either on plain abdominal film and ultrasonography or low-dose CT scan.

  19. Increasingly minimal bias routing

    Energy Technology Data Exchange (ETDEWEB)

    Bataineh, Abdulla; Court, Thomas; Roweth, Duncan

    2017-02-21

    A system and algorithm configured to generate diversity at the traffic source so that packets are uniformly distributed over all of the available paths, but to increase the likelihood of taking a minimal path with each hop the packet takes. This is achieved by configuring routing biases so as to prefer non-minimal paths at the injection point, but increasingly prefer minimal paths as the packet proceeds, referred to herein as Increasing Minimal Bias (IMB).

  20. 小儿上尿路结石梗阻致急性肾衰的手术治疗%Acute Renal Failure Caused by Upper Urinary Lithiasis Obstruction in Children

    Institute of Scientific and Technical Information of China (English)

    关汉礼; 王英; 地力夏提; 米吉提沙克; 艾尔肯; 毛苏木

    1999-01-01

    Objective To review the efficacy of operative treatment for acute renal failure resulted from obstruction of upper urinary lithiasis.Methods Seventy-four cases(male 51,female 23)of acute renal failure caused by upper urinary lithiasis were admitted from 1985 to 1997.The age ranged from 4 months to 11 years(mean 2 yrs and 10 mons).Prompt drainge by insertion of percutaneous nephrostomy tube and ictus therapy with diuretic mixture were indicated until the clinical situation of renal failure improved.Results Among the 74 patients(kidney 62,ureter 19,bladder 3),who underwent surgical removal of the lithiasis,67 survived and 7 died.Conclusions The operative management of adults with urinary lithiasis is also fit for children.When patients with bilateral lesions,the general situation will be reversed by unilateral releasing from the obstruction.The function of the contralateral kidney after an selective operation is still kept well.%目的 探讨小儿上尿路结石梗阻造成急性肾衰的病理生理.分析手术治疗的临床疗效.方法 先行利尿合剂冲击疗法或经皮肾穿刺置管引流,改善垂危状况后手术取石解除梗阻.结果 对74例患儿的62个肾、19根输尿管、3个膀胱切开取石.67例获痊愈、7例死亡.结论 应用于成人的手术方法 也同样适用于小儿.手术解除一侧梗阻即可逆转全身情况,对侧择期手术肾功能并未发现代偿性减退或丧失.

  1. Locally minimal topological groups

    OpenAIRE

    Außenhofer, Lydia; Chasco, María Jesús; Dikranjan, Dikran; Domínguez, Xabier

    2009-01-01

    A Hausdorff topological group $(G,\\tau)$ is called locally minimal if there exists a neighborhood $U$ of 0 in $\\tau$ such that $U$ fails to be a neighborhood of zero in any Hausdorff group topology on $G$ which is strictly coarser than $\\tau.$ Examples of locally minimal groups are all subgroups of Banach-Lie groups, all locally compact groups and all minimal groups. Motivated by the fact that locally compact NSS groups are Lie groups, we study the connection between local minimality and the ...

  2. On minimal round functions

    NARCIS (Netherlands)

    Khimshiashvili, G.; Siersma, D.

    2001-01-01

    We describe the structure of minimal round functions on closed surfaces and three-folds. The minimal possible number of critical loops is determined and typical non-equisingular round function germs are interpreted in the spirit of isolated line singularities. We also discuss a version of Lusternik-

  3. Minimal change disease

    Science.gov (United States)

    ... get worse You develop new symptoms, including side effects from the medicines used to treat the disorder Alternative Names Minimal change nephrotic syndrome; Nil disease; Lipoid nephrosis; Idiopathic nephrotic syndrome of childhood Images ...

  4. Minimal Orderings Revisited

    Energy Technology Data Exchange (ETDEWEB)

    Peyton, B.W.

    1999-07-01

    When minimum orderings proved too difficult to deal with, Rose, Tarjan, and Leuker instead studied minimal orderings and how to compute them (Algorithmic aspects of vertex elimination on graphs, SIAM J. Comput., 5:266-283, 1976). This paper introduces an algorithm that is capable of computing much better minimal orderings much more efficiently than the algorithm in Rose et al. The new insight is a way to use certain structures and concepts from modern sparse Cholesky solvers to re-express one of the basic results in Rose et al. The new algorithm begins with any initial ordering and then refines it until a minimal ordering is obtained. it is simple to obtain high-quality low-cost minimal orderings by using fill-reducing heuristic orderings as initial orderings for the algorithm. We examine several such initial orderings in some detail.

  5. Minimal Markov Models

    CERN Document Server

    Gonzalez-Lopez, Jesus E Garcia Veronica A

    2010-01-01

    In this work we introduce a new and richer class of finite order Markov chain models and address the following model selection problem: find the Markov model with the minimal set of parameters (minimal Markov model) which is necessary to represent a source as a Markov chain of finite order. Let us call $M$ the order of the chain and $A$ the finite alphabet, to determine the minimal Markov model, we define an equivalence relation on the state space $A^{M}$, such that all the sequences of size $M$ with the same transition probabilities are put in the same category. In this way we have one set of $(|A|-1)$ transition probabilities for each category, obtaining a model with a minimal number of parameters. We show that the model can be selected consistently using the Bayesian information criterion.

  6. Ruled Laguerre minimal surfaces

    KAUST Repository

    Skopenkov, Mikhail

    2011-10-30

    A Laguerre minimal surface is an immersed surface in ℝ 3 being an extremal of the functional ∫ (H 2/K-1)dA. In the present paper, we prove that the only ruled Laguerre minimal surfaces are up to isometry the surfaces ℝ (φλ) = (Aφ, Bφ, Cφ + D cos 2φ) + λ(sin φ, cos φ, 0), where A,B,C,D ε ℝ are fixed. To achieve invariance under Laguerre transformations, we also derive all Laguerre minimal surfaces that are enveloped by a family of cones. The methodology is based on the isotropic model of Laguerre geometry. In this model a Laguerre minimal surface enveloped by a family of cones corresponds to a graph of a biharmonic function carrying a family of isotropic circles. We classify such functions by showing that the top view of the family of circles is a pencil. © 2011 Springer-Verlag.

  7. Radiation Safety in Pediatric Orthopaedics.

    Science.gov (United States)

    Caird, Michelle S

    2015-01-01

    Patients, surgeons, and staff are exposed to ionizing radiation in pediatric orthopaedic surgery from diagnostic studies and imaging associated with procedures. Estimating radiation dose to pediatric patients is based on complex algorithms and dose to surgeons and staff is based on dosimeter monitoring. Surgeons can decrease radiation exposure to patients with careful and thoughtful ordering of diagnostic studies and by minimizing exposure intraoperatively. Surgeon and staff radiation exposure can be minimized with educational programs, proper shielding and positioning intraoperatively, and prudent use of intraoperative imaging. Overall, better awareness among pediatric orthopaedic surgeons of our role in radiation exposure can lead to improvements in radiation safety.

  8. Next-to-Minimal SOFTSUSY

    CERN Document Server

    Allanach, B C; Tunstall, Lewis C; Voigt, A; Williams, A G

    2013-01-01

    We describe an extension to the SOFTSUSY program that provides for the calculation of the sparticle spectrum in the Next-to-Minimal Supersymmetric Standard Model (NMSSM), where a chiral superfield that is a singlet of the Standard Model gauge group is added to the Minimal Supersymmetric Standard Model (MSSM) fields. Often, a $\\mathbb{Z}_{3}$ symmetry is imposed upon the model. SOFTSUSY can calculate the spectrum in this case as well as the case where general $\\mathbb{Z}_{3}$ violating (denoted as $\\,\\mathbf{\\backslash}\\mkern-11.0mu{\\mathbb{Z}}_{3}$) terms are added to the soft supersymmetry breaking terms and the superpotential. The user provides a theoretical boundary condition for the couplings and mass terms of the singlet. Radiative electroweak symmetry breaking data along with electroweak and CKM matrix data are used as weak-scale boundary conditions. The renormalisation group equations are solved numerically between the weak scale and a high energy scale using a nested iterative algorithm. This paper se...

  9. Locally minimal topological groups

    CERN Document Server

    enhofer, Lydia Au\\ss; Dikranjan, Dikran; Domínguez, Xabier

    2009-01-01

    A Hausdorff topological group $(G,\\tau)$ is called locally minimal if there exists a neighborhood $U$ of 0 in $\\tau$ such that $U$ fails to be a neighborhood of zero in any Hausdorff group topology on $G$ which is strictly coarser than $\\tau.$ Examples of locally minimal groups are all subgroups of Banach-Lie groups, all locally compact groups and all minimal groups. Motivated by the fact that locally compact NSS groups are Lie groups, we study the connection between local minimality and the NSS property, establishing that under certain conditions, locally minimal NSS groups are metrizable. A symmetric subset of an abelian group containing zero is said to be a GTG set if it generates a group topology in an analogous way as convex and symmetric subsets are unit balls for pseudonorms on a vector space. We consider topological groups which have a neighborhood basis at zero consisting of GTG sets. Examples of these locally GTG groups are: locally pseudo--convex spaces, groups uniformly free from small subgroups (...

  10. Randomized comparison of operator radiation exposure comparing transradial and transfemoral approach for percutaneous coronary procedures: Rationale and design of the minimizing adverse haemorrhagic events by TRansradial access site and systemic implementation of angioX - RAdiation Dose study (RAD-MATRIX)

    NARCIS (Netherlands)

    A. Sciahbasi (Alessandro); A. Calabrò (Anna); A. Sarandrea (Alessandro); S. Rigattieri (Stefano); F. Tomassini (Francesco); G. Sardella (Gennaro); D. Zavalloni (Dennis); B. Cortese (Bernardo); U. Limbruno (Ugo); M. Tebaldi (Matteo); A. Gagnor (Andrea); P. Rubartelli (Paolo); A. Zingarelli (Antonio); M. Valgimigli (Marco)

    2014-01-01

    textabstractBackground: Radiation absorbed by interventional cardiologists is a frequently under-evaluated important issue. Aim is to compare radiation dose absorbed by interventional cardiologists during percutaneous coronary procedures for acute coronary syndromes comparing transradial and transfe

  11. Adaptive Alternating Minimization Algorithms

    CERN Document Server

    Niesen, Urs; Wornell, Gregory

    2007-01-01

    The classical alternating minimization (or projection) algorithm has been successful in the context of solving optimization problems over two variables or equivalently of finding a point in the intersection of two sets. The iterative nature and simplicity of the algorithm has led to its application to many areas such as signal processing, information theory, control, and finance. A general set of sufficient conditions for the convergence and correctness of the algorithm is quite well-known when the underlying problem parameters are fixed. In many practical situations, however, the underlying problem parameters are changing over time, and the use of an adaptive algorithm is more appropriate. In this paper, we study such an adaptive version of the alternating minimization algorithm. As a main result of this paper, we provide a general set of sufficient conditions for the convergence and correctness of the adaptive algorithm. Perhaps surprisingly, these conditions seem to be the minimal ones one would expect in ...

  12. Minimal E$_{0}$-semigroups

    CERN Document Server

    Arveson, W

    1995-01-01

    It is known that every semigroup of normal completely positive maps of a von Neumann can be ``dilated" in a particular way to an E_0-semigroup acting on a larger von Neumann algebra. The E_0-semigroup is not uniquely determined by the completely positive semigroup; however, it is unique (up to conjugacy) provided that certain conditions of {\\it minimality} are met. Minimality is a subtle property, and it is often not obvious if it is satisfied for specific examples even in the simplest case where the von Neumann algebra is \\Cal B(H). In this paper we clarify these issues by giving a new characterization of minimality in terms projective cocycles and their limits. Our results are valid for semigroups of endomorphisms acting on arbitrary von Neumann algebras with separable predual.

  13. Minimal constrained supergravity

    Directory of Open Access Journals (Sweden)

    N. Cribiori

    2017-01-01

    Full Text Available We describe minimal supergravity models where supersymmetry is non-linearly realized via constrained superfields. We show that the resulting actions differ from the so called “de Sitter” supergravities because we consider constraints eliminating directly the auxiliary fields of the gravity multiplet.

  14. Minimally invasive periodontal therapy.

    Science.gov (United States)

    Dannan, Aous

    2011-10-01

    Minimally invasive dentistry is a concept that preserves dentition and supporting structures. However, minimally invasive procedures in periodontal treatment are supposed to be limited within periodontal surgery, the aim of which is to represent alternative approaches developed to allow less extensive manipulation of surrounding tissues than conventional procedures, while accomplishing the same objectives. In this review, the concept of minimally invasive periodontal surgery (MIPS) is firstly explained. An electronic search for all studies regarding efficacy and effectiveness of MIPS between 2001 and 2009 was conducted. For this purpose, suitable key words from Medical Subject Headings on PubMed were used to extract the required studies. All studies are demonstrated and important results are concluded. Preliminary data from case cohorts and from many studies reveal that the microsurgical access flap, in terms of MIPS, has a high potential to seal the healing wound from the contaminated oral environment by achieving and maintaining primary closure. Soft tissues are mostly preserved and minimal gingival recession is observed, an important feature to meet the demands of the patient and the clinician in the esthetic zone. However, although the potential efficacy of MIPS in the treatment of deep intrabony defects has been proved, larger studies are required to confirm and extend the reported positive preliminary outcomes.

  15. Logarithmic Superconformal Minimal Models

    CERN Document Server

    Pearce, Paul A; Tartaglia, Elena

    2013-01-01

    The higher fusion level logarithmic minimal models LM(P,P';n) have recently been constructed as the diagonal GKO cosets (A_1^{(1)})_k oplus (A_1^{(1)})_n / (A_1^{(1)})_{k+n} where n>0 is an integer fusion level and k=nP/(P'-P)-2 is a fractional level. For n=1, these are the logarithmic minimal models LM(P,P'). For n>1, we argue that these critical theories are realized on the lattice by n x n fusion of the n=1 models. For n=2, we call them logarithmic superconformal minimal models LSM(p,p') where P=|2p-p'|, P'=p' and p,p' are coprime, and they share the central charges of the rational superconformal minimal models SM(P,P'). Their mathematical description entails the fused planar Temperley-Lieb algebra which is a spin-1 BMW tangle algebra with loop fugacity beta_2=x^2+1+x^{-2} and twist omega=x^4 where x=e^{i(p'-p)pi/p'}. Examples are superconformal dense polymers LSM(2,3) with c=-5/2, beta_2=0 and superconformal percolation LSM(3,4) with c=0, beta_2=1. We calculate the free energies analytically. By numerical...

  16. Prostate resection - minimally invasive

    Science.gov (United States)

    ... invasive URL of this page: //medlineplus.gov/ency/article/007415.htm Prostate resection - minimally invasive To use ... into your bladder instead of out through the urethra ( retrograde ... on New Developments in Prostate Cancer and Prostate Diseases. Evaluation and treatment of lower ...

  17. X-rays sensing properties of MEH-PPV, Alq₃ and additive components: a new organic dosimeter as a candidate for minimizing the risk of accidents of patients undergoing radiation oncology.

    Science.gov (United States)

    Schimitberger, T; Ferreira, G R; Akcelrud, L C; Saraiva, M F; Bianchi, R F

    2013-01-01

    In this paper, we report our experimental design in searching a smart and easy-to-read dosimeter used to detect 6 MV X-rays for improving patient safety in radiation oncology. The device was based on an organic emissive solutions of poly(2-methoxy-5(2'-ethylhexyloxy)-p-phenylenevinylene) (MEH-PPV), aluminum-tris-(8-hydroxyquinoline) (Alq₃) and additive components which were characterized by UV-Vis absorption, photoluminescence and CIE color coordinate diagram. The optical properties of MEH-PPV/Alq₃ solutions have been examined as function of radiation dose over the range of 0-100 Gy. It has shown that MEH-PPV/Alq₃ solutions are specifically sensitive to X-rays, since the effect of radiation on this organic system is strongly correlated with the efficient spectral overlap between Alq₃ emission and the absorption of degraded MEH-PPV, which alters the color and photoemission of MEH-PPV/Alq₃ mixtures from red to yellow, and then to green. The rate of this change is more sensitive when MEH-PPV/Alq₃ is irradiated in the presence of benzoyl peroxide than when in the presence of hindered phenolic stabilizers, respectively, an accelerator and an inhibitor to activate or inhibit free radical formation. This gives rise to optimize the response curve of the dosimeter. It is clear from the experimental results that organic emissive semiconductors have potential to be used as dedicated and low-cost dosimeters to provide an independent check of beam output of a linear accelerator and therefore to give patients the opportunity to have information on the dose prescription or equipment-related problems a few minutes before being exposed to radiation.

  18. Evaluation of the effects of gamma radiation on the quality of pineapple (Ananas comosus (L.) Meer) cv. Smooth Cayenne minimally processed, storaged on differents temperatures and packages;Avaliacao dos efeitos da radiacao gama na qualidade de abacaxi (Ananas comosus (L.) Meer) cv. Smooth Cayenne minimamente processado, armazenado em diferentes temperaturas e embalagens

    Energy Technology Data Exchange (ETDEWEB)

    Leite, Daniela Terenzi Stuchi

    2006-07-01

    The present work aimed to verify the effects of gamma radiation (doses until 2 kGy), types of packages and temperatures of storage (5, 8 e 12 deg C) on the physicochemical characteristics, on the microbiological contamination and on the sensorial characteristics of pineapple 'Smooth Cayenne' minimally processed. The fruits were selected, washed; peeled and cutted transverse and the slices cutted were cutted on two or for pieces. The pieces were immersed in chlorinated water (100 mg/L) for 3 minutes, flowing and package, irradiated and stored. According with the results obtained in thi present work it was concluded that bigger the temperature of storage more quickly were the browning of the fruits. The loss of fresh weight of pineapple was bigger in the packages of polystyrene comparing with PET package when both are covered with PVC film and smaller in the PET packages covered with the same material. Doses of gamma radiation until 2 kGy did not change the physico-chemical and sensorial characteristics of pineapple 'Smooth Cayenne' minimally processed. The microbiological growth on the pieces of the processed fruit was smaller on the biggest dose. All the samples were is in good conditions for the human consume. (author)

  19. Experiencia en Cuba del tratamiento de la litiasis renoureteral con litotricia extracorpórea por ondas de choque en niños Cuban experience in the treatment of renouretheral lithiasis in children by using extracorporeal shock wave lithotripsy

    Directory of Open Access Journals (Sweden)

    María Victoria Labrada Rodríguez

    2012-06-01

    Full Text Available Introducción: la litiasis urinaria en el niño resulta una enfermedad poco frecuente si se compara con su incidencia en el adulto. Objetivos: describir el resultado del tratamiento en Cuba de la litiasis del aparato urinario en niños, mediante la litotricia extracorpórea por ondas de choque, así como validar la eficacia del método. Métodos: la muestra corresponde a 227 niños, tratados en el Centro de Tratamiento de la Litiasis Urinaria del Hospital Clinicoquirúrgico "Hermanos Ameijeiras'' de La Habana, entre abril de 1986 y octubre de 2011, utilizando 3 tipos de litotritores: el HM3 (Dornier, Lithostar Plus (Siemens y Medical Modulith® SLX (Storz. Resultados: las edades límites fueron 2 y 18 años. De manera general resultó similar el total de pacientes tratados del sexo femenino que el masculino (51 %/49 %. El síntoma predominante fue el cólico nefrítico con cálculos renales (81,9 %, y en el uréter (18,1 %. La superficie media fue de 1,20 cm². Se utilizó anestesia general orotraqueal (34,4 % y general intravenosa (65,6 %. Los retratamientos fueron necesarios en 8 casos (3,52 %. Las complicaciones fueron la infección urinaria aguda (3,08 % y el hematoma subcapsular renal (0,88 %. Resultó libre de material litiásico el 96,04 %. Conclusiones: la terapéutica mediante la litotricia extracorpórea por ondas de choque resulta efectiva, con baja tasa de morbilidad y de complicaciones graves, por lo que creemos debe defenderse científicamente como la primera opción terapéutica en la resolución de la litiasis urinaria en estas edades. Debe recordarse que eliminar el cálculo no es suficiente, hay que identificar la enfermedad, su tratamiento de fondo, y evitar las recidivas.Introduction: urinary lithiasis is a rare disease in children if compared with its incidence on the adults. Objectives: to describe the results of the treatment of urinary lithiasis in children in Cuba, by using extracorporeal shock wave lithrotripsy, and to

  20. Minimal hepatic encephalopathy.

    Science.gov (United States)

    Zamora Nava, Luis Eduardo; Torre Delgadillo, Aldo

    2011-06-01

    The term minimal hepatic encephalopathy (MHE) refers to the subtle changes in cognitive function, electrophysiological parameters, cerebral neurochemical/neurotransmitter homeostasis, cerebral blood flow, metabolism, and fluid homeostasis that can be observed in patients with cirrhosis who have no clinical evidence of hepatic encephalopathy; the prevalence is as high as 84% in patients with hepatic cirrhosis. Physician does generally not perceive cirrhosis complications, and neuropsychological tests and another especial measurement like evoked potentials and image studies like positron emission tomography can only make diagnosis. Diagnosis of minimal hepatic encephalopathy may have prognostic and therapeutic implications in cirrhotic patients. The present review pretends to explore the clinic, therapeutic, diagnosis and prognostic aspects of this complication.

  1. Minimal triangulations of simplotopes

    CERN Document Server

    Seacrest, Tyler

    2009-01-01

    We derive lower bounds for the size of simplicial covers of simplotopes, which are products of simplices. These also serve as lower bounds for triangulations of such polytopes, including triangulations with interior vertices. We establish that a minimal triangulation of a product of two simplices is given by a vertex triangulation, i.e., one without interior vertices. For products of more than two simplices, we produce bounds for products of segments and triangles. Our analysis yields linear programs that arise from considerations of covering exterior faces and exploiting the product structure of these polytopes. Aside from cubes, these are the first known lower bounds for triangulations of simplotopes with three or more factors. We also construct a minimal triangulation for the product of a triangle and a square, and compare it to our lower bound.

  2. Minimal Composite Inflation

    DEFF Research Database (Denmark)

    Channuie, Phongpichit; Jark Joergensen, Jakob; Sannino, Francesco

    2011-01-01

    We investigate models in which the inflaton emerges as a composite field of a four dimensional, strongly interacting and nonsupersymmetric gauge theory featuring purely fermionic matter. We show that it is possible to obtain successful inflation via non-minimal coupling to gravity, and that the u......We investigate models in which the inflaton emerges as a composite field of a four dimensional, strongly interacting and nonsupersymmetric gauge theory featuring purely fermionic matter. We show that it is possible to obtain successful inflation via non-minimal coupling to gravity......, and that the underlying dynamics is preferred to be near conformal. We discover that the compositeness scale of inflation is of the order of the grand unified energy scale....

  3. Wetting and Minimal Surfaces

    CERN Document Server

    Bachas, C; Wiese, K J; Bachas, Constantin; Doussal, Pierre Le; Wiese, Kay Joerg

    2006-01-01

    We study minimal surfaces which arise in wetting and capillarity phenomena. Using conformal coordinates, we reduce the problem to a set of coupled boundary equations for the contact line of the fluid surface, and then derive simple diagrammatic rules to calculate the non-linear corrections to the Joanny-de Gennes energy. We argue that perturbation theory is quasi-local, i.e. that all geometric length scales of the fluid container decouple from the short-wavelength deformations of the contact line. This is illustrated by a calculation of the linearized interaction between contact lines on two opposite parallel walls. We present a simple algorithm to compute the minimal surface and its energy based on these ideas. We also point out the intriguing singularities that arise in the Legendre transformation from the pure Dirichlet to the mixed Dirichlet-Neumann problem.

  4. Minimal Walking Technicolor

    DEFF Research Database (Denmark)

    Frandsen, Mads Toudal

    2007-01-01

    I report on our construction and analysis of the effective low energy Lagrangian for the Minimal Walking Technicolor (MWT) model. The parameters of the effective Lagrangian are constrained by imposing modified Weinberg sum rules and by imposing a value for the S parameter estimated from the under...... the underlying Technicolor theory. The constrained effective Lagrangian allows for an inverted vector vs. axial-vector mass spectrum in a large part of the parameter space....

  5. On Minimal Constraint Networks

    CERN Document Server

    Gottlob, Georg

    2011-01-01

    In a minimal binary constraint network, every tuple of a constraint relation can be extended to a solution. It was conjectured that computing a solution to such a network is NP complete. We prove this conjecture true and show that the problem remains NP hard even in case the total domain of all values that may appear in the constraint relations is bounded by a constant.

  6. Application of the microbiological method DEFT/APC and DNA comet assay to detect ionizing radiation processing of minimally processed vegetables; Aplicacao do metodo microbiologico DEFT/APC e do teste do cometa na deteccao do tratamento com radiacao ionizante de hortalicas minimamente processadas

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Michel Mozeika

    2008-07-01

    Marketing of minimally processed vegetables (MPV) are gaining impetus due to its convenience, freshness and apparent healthy. However, minimal processing does not reduce pathogenic microorganisms to safe levels. Food irradiation is used to extend the shelf life and inactivation of food-borne pathogens, Its combination with minimal processing could improve the safety and quality of MPV. Two different food irradiation detection methods, a biological, the DEFT/APC, and another biochemical, the DNA Comet Assay were applied to MPV in order to test its applicability to detect irradiation treatment. DEFT/APC is a microbiological screening method based on the use of the direct epi fluorescent filter technique (DEFT) and the aerobic plate count (APC). DNA Comet Assay detects DNA damage due to ionizing radiation. Samples of lettuce, chard, watercress, dandelion, kale, chicory, spinach, cabbage from retail market were irradiated O.5 kGy and 1.0 kGy using a {sup 60} Co facility. Irradiation treatment guaranteed at least 2 log cycle reduction for aerobic and psychotropic microorganisms. In general, with increasing radiation doses, DEFT counts remained similar independent of irradiation processing while APC counts decreased gradually. The difference of the two counts gradually increased with dose increment in all samples. It could be suggested that a DEFT/APC difference over 2.0 log would be a criteria to judge if a MPV was treated by irradiation. DNA Comet Assay allowed distinguishing non-irradiated samples from irradiated ones, which showed different types of comets owing to DNA fragmentation. Both DEFT/APC method and DNA Comet Assay would be satisfactorily used as a screening method for indicating irradiation processing. (author)

  7. [Minimally invasive surgery in pediatric patients within a general urology department].

    Science.gov (United States)

    Ríos, Jorge Subirá; Zalabardo, José Manuel Sánchez; Gil, Joaquín Navarro; Conejos, José Ignacio Hijazo; Alonso, Jesús García-Magariño; Calero, David García; López, José Antonio López; Uría, José Gabriel Valdivia

    2008-01-01

    The advances of minimally invasive surgery in urology over the last years have enabled a progressive and constant implementation of endourology and laparoscopy in pediatric patients. We perform a review of our experience, as a general hospital, with minimally invasive surgery performed in pediatric patients over the last ten years. We retrospectively analyzed the endourological and laparoscopic operations performed between 1997 and 2007 in children up to the age of 16 years, collecting data about patient's age and gender, type of disease, techniques, anesthesia, and perioperative events. seventy-two surgical operations were performed in patients with an age range between 28 days and 16 years, with a mean age of 6.8 years. 56% of the patients were boys and 44% girls. Indications for surgery was vesicoureteral reflux (VUR) in 28 cases (38.8%); lithiasis 17 cases (23.6%) which were distributed in 4 cystolithotripsies, 9 ureterorenoscopy with lithotripsy, one pure percutaneous nephrolithotomy and three mixed; ureterocele 9 cases (12.5%); urethral obstruction 7 cases (9.7%); 3 diagnostic laparoscopies for cryptorchidism (4. 1%), 2 laparoscopic procedures for cystic pathology (2.7%), another 2 laparoscopic renal biopsies (2.7%), and one laparoscopic repair of a ureteropyelic junction syndrome; 1 case of emergency percutaneous nephrostomy in the supine position after open pyeloplasty with subsequent reoperation with percutaneous resection of a granuloma; and 1 case of botulin toxin injection into the detrusor muscle. The consolidation of pediatric endourology in our department, and more recently laparoscopy, has contributed to improve the quality of care in pediatric patients; it has been achieved thanks to our previous know-how in general endourological techniques and the existence of adequate technical and human resources.

  8. Minimally Invasive Parathyroidectomy

    Directory of Open Access Journals (Sweden)

    Lee F. Starker

    2011-01-01

    Full Text Available Minimally invasive parathyroidectomy (MIP is an operative approach for the treatment of primary hyperparathyroidism (pHPT. Currently, routine use of improved preoperative localization studies, cervical block anesthesia in the conscious patient, and intraoperative parathyroid hormone analyses aid in guiding surgical therapy. MIP requires less surgical dissection causing decreased trauma to tissues, can be performed safely in the ambulatory setting, and is at least as effective as standard cervical exploration. This paper reviews advances in preoperative localization, anesthetic techniques, and intraoperative management of patients undergoing MIP for the treatment of pHPT.

  9. Minimal E6 unification

    Science.gov (United States)

    Susič, Vasja

    2016-06-01

    A realistic model in the class of renormalizable supersymmetric E6 Grand Unified Theories is constructed. Its matter sector consists of 3 × 27 representations, while the Higgs sector is 27 +27 ¯+35 1'+35 1' ¯+78 . An analytic solution for a Standard Model vacuum is found and the Yukawa sector analyzed. It is argued that if one considers the increased predictability due to only two symmetric Yukawa matrices in this model, it can be considered a minimal SUSY E6 model with this type of matter sector. This contribution is based on Ref. [1].

  10. Minimal Higgs inflation

    CERN Document Server

    Maity, Debaprasad

    2016-01-01

    In this paper we propose two simple minimal Higgs inflation scenarios through a simple modification of the Higgs potential, as opposed to the usual non-minimal Higgs-gravity coupling prescription. The modification is done in such a way that it creates a flat plateau for a huge range of field values at the inflationary energy scale $\\mu \\simeq (\\lambda)^{1/4} \\alpha$. Assuming the perturbative Higgs quartic coupling, $\\lambda \\simeq {\\cal O}(1)$, for both the models inflation energy scale turned out to be $\\mu \\simeq (10^{14}, 10^{15})$ GeV, and prediction of all the cosmologically relevant quantities, $(n_s,r,dn_s^k)$, fit extremely well with observations made by PLANCK. Considering observed central value of the scalar spectral index, $n_s= 0.968$, our two models predict efolding number, $N = (52,47)$. Within a wide range of viable parameter space, we found that the prediction of tensor to scalar ratio $r (\\leq 10^{-5})$ is far below the current experimental sensitivity to be observed in the near future. The ...

  11. Logarithmic superconformal minimal models

    Science.gov (United States)

    Pearce, Paul A.; Rasmussen, Jørgen; Tartaglia, Elena

    2014-05-01

    The higher fusion level logarithmic minimal models {\\cal LM}(P,P';n) have recently been constructed as the diagonal GKO cosets {(A_1^{(1)})_k\\oplus (A_1^ {(1)})_n}/ {(A_1^{(1)})_{k+n}} where n ≥ 1 is an integer fusion level and k = nP/(P‧- P) - 2 is a fractional level. For n = 1, these are the well-studied logarithmic minimal models {\\cal LM}(P,P')\\equiv {\\cal LM}(P,P';1). For n ≥ 2, we argue that these critical theories are realized on the lattice by n × n fusion of the n = 1 models. We study the critical fused lattice models {\\cal LM}(p,p')_{n\\times n} within a lattice approach and focus our study on the n = 2 models. We call these logarithmic superconformal minimal models {\\cal LSM}(p,p')\\equiv {\\cal LM}(P,P';2) where P = |2p - p‧|, P‧ = p‧ and p, p‧ are coprime. These models share the central charges c=c^{P,P';2}=\\frac {3}{2}\\big (1-{2(P'-P)^2}/{P P'}\\big ) of the rational superconformal minimal models {\\cal SM}(P,P'). Lattice realizations of these theories are constructed by fusing 2 × 2 blocks of the elementary face operators of the n = 1 logarithmic minimal models {\\cal LM}(p,p'). Algebraically, this entails the fused planar Temperley-Lieb algebra which is a spin-1 Birman-Murakami-Wenzl tangle algebra with loop fugacity β2 = [x]3 = x2 + 1 + x-2 and twist ω = x4 where x = eiλ and λ = (p‧- p)π/p‧. The first two members of this n = 2 series are superconformal dense polymers {\\cal LSM}(2,3) with c=-\\frac {5}{2}, β2 = 0 and superconformal percolation {\\cal LSM}(3,4) with c = 0, β2 = 1. We calculate the bulk and boundary free energies analytically. By numerically studying finite-size conformal spectra on the strip with appropriate boundary conditions, we argue that, in the continuum scaling limit, these lattice models are associated with the logarithmic superconformal models {\\cal LM}(P,P';2). For system size N, we propose finitized Kac character formulae of the form q^{-{c^{P,P';2}}/{24}+\\Delta ^{P,P';2} _{r

  12. Natural minimal dark matter

    CERN Document Server

    Fabbrichesi, Marco

    2015-01-01

    We show how the Higgs boson mass is protected from the potentially large corrections due to the introduction of minimal dark matter if the new physics sector is made supersymmetric. The fermionic dark matter candidate (a 5-plet of $SU(2)_L$) is accompanied by a scalar state. The weak gauge sector is made supersymmetric and the Higgs boson is embedded in a supersymmetric multiplet. The remaining standard model states are non-supersymmetric. Non vanishing corrections to the Higgs boson mass only appear at three-loop level and the model is natural for dark matter masses up to 15 TeV--a value larger than the one required by the cosmological relic density. The construction presented stands as an example of a general approach to naturalness that solves the little hierarchy problem which arises when new physics is added beyond the standard model at an energy scale around 10 TeV.

  13. Minimal Hepatic Encephalopathy

    Directory of Open Access Journals (Sweden)

    Laura M Stinton

    2013-01-01

    Full Text Available Minimal hepatic encephalopathy (MHE is the earliest form of hepatic encephalopathy and can affect up to 80% of cirrhotic patients. By definition, it has no obvious clinical manifestation and is characterized by neurocognitive impairment in attention, vigilance and integrative function. Although often not considered to be clinically relevant and, therefore, not diagnosed or treated, MHE has been shown to affect daily functioning, quality of life, driving and overall mortality. The diagnosis of MHE has traditionally been achieved through neuropsychological examination, psychometric tests or the newer critical flicker frequency test. A new smartphone application (EncephalApp Stroop Test may serve to function as a screening tool for patients requiring further testing. In addition to physician reporting and driving restrictions, medical treatment for MHE includes non-absorbable disaccharides (eg, lactulose, probiotics or rifaximin. Liver transplantation may not result in reversal of the cognitive deficits associated with MHE.

  14. Minimally extended SILH

    Energy Technology Data Exchange (ETDEWEB)

    Chala, Mikael [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Valencia Univ. (Spain). Dept. de Fisica Teorica y IFIC; Durieux, Gauthier; Matsedonskyi, Oleksii [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Grojean, Christophe [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Humboldt-Univ. Berlin (Germany). Inst. fuer Physik; Lima, Leonardo de [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Univ. Estadual Paulista, Sao Paulo (Brazil). Inst. de Fisica Teorica

    2017-03-15

    Higgs boson compositeness is a phenomenologically viable scenario addressing the hierarchy problem. In minimal models, the Higgs boson is the only degree of freedom of the strong sector below the strong interaction scale. We present here the simplest extension of such a framework with an additional composite spin-zero singlet. To this end, we adopt an effective field theory approach and develop a set of rules to estimate the size of the various operator coefficients, relating them to the parameters of the strong sector and its structural features. As a result, we obtain the patterns of new interactions affecting both the new singlet and the Higgs boson's physics. We identify the characteristics of the singlet field which cause its effects on Higgs physics to dominate over the ones inherited from the composite nature of the Higgs boson. Our effective field theory construction is supported by comparisons with explicit UV models.

  15. Resource Minimization Job Scheduling

    Science.gov (United States)

    Chuzhoy, Julia; Codenotti, Paolo

    Given a set J of jobs, where each job j is associated with release date r j , deadline d j and processing time p j , our goal is to schedule all jobs using the minimum possible number of machines. Scheduling a job j requires selecting an interval of length p j between its release date and deadline, and assigning it to a machine, with the restriction that each machine executes at most one job at any given time. This is one of the basic settings in the resource-minimization job scheduling, and the classical randomized rounding technique of Raghavan and Thompson provides an O(logn/loglogn)-approximation for it. This result has been recently improved to an O(sqrt{log n})-approximation, and moreover an efficient algorithm for scheduling all jobs on O((OPT)^2) machines has been shown. We build on this prior work to obtain a constant factor approximation algorithm for the problem.

  16. Minimize reference sideband generation in microwave PLLs

    Science.gov (United States)

    Goldman, Stan

    1991-02-01

    The processes responsible for producing reference sidebands are outlined, and the sources of coupling to the microwave voltage-controlled oscillator (VCO) tune line including power-supply-generated signals, TTL-controlled interface signals, intermediate programmable-divider signals, and radiated TTL signals are discussed. It is noted that filtering alone is inadequate for reference-sideband suppression, while minimizing the tuning slope and maximizing the reference frequency will result in a reduced reference-sideband level. Minimizing offset currents by using a differential amplifier connection may reduce the reference-sideband level aggravated by an opamp. The selection of a TTL, ECL, or GaAs phase/frequency detector can determine the level of reference sidebands, as well as PCB isolation techniques.

  17. O que há de novo no diagnóstico e tratamento da litíase urinária? What's new in the diagnosis and management of urinary lithiasis?

    Directory of Open Access Journals (Sweden)

    Eduardo Mazzucchi

    2009-01-01

    Full Text Available OBJETIVO. Atualizar aspectos do diagnóstico e do tratamento da litíase urinária. MÉTODOS. Uma revisão dos principais artigos publicados sobre o tema em revistas indexadas no "Medline" entre 1979 e 2009. RESULTADOS. A ocorrência de cálculos é maior em pacientes com IMC > 30. A TC sem contraste promove o diagnóstico correto em até 98% dos casos. O uso de bloqueadores alfa-adrenérgicos aumenta a eliminação de cálculos ureterais menores que 8 mm em 29%. O índice de pacientes livres de cálculo após LEOC varia entre 35% e 91%, conforme seu tamanho e localização. Cálculos renais maiores que 2 cm são eliminados pela NLPC entre 60% e 100% dos casos. Cálculos de ureter distal são tratados com sucesso em até 94% dos casos pela ureteroscopia semirrígida contra 74% da LEOC. Já para cálculos de ureter superior as taxas de sucesso situam-se entre 77% e 91% para ureteroscopia e 41% e 82% para a LEOC. CONCLUSÃO. A associação da calculose urinária com obesidade e Diabetes mellitus está bem estabelecida. A TC sem contraste é atualmente o padrão-ouro no diagnóstico da litíase urinária. A LEOC é o método de eleição em nosso meio para tratamento de cálculos renais menores que 2 cm e com densidade tomográfica OBJECTIVE. To review developments in the diagnosis and treatment of urinary lithiasis. METHODS. A review of the most important articles on the subject published in Medline indexed periodicals between 1979 and 2009.RESULTS. Stones occur with greater frequency among people with BMI > 30. Computerized tomography without contrast provides the correct diagnosis in up to 98% of cases. Alpha-adrenergic blockers increase elimination of ureteral calculi smaller than 8 mm by 29%. The proportion of patients free from calculi after ESWL varies from 35% to 91%, depending on size and location. In between 60% and 100% of cases, renal calculi larger than 2 cm are eliminated with PCNL. Calculi of the distal ureter are successfully

  18. Minimal Log Gravity

    CERN Document Server

    Giribet, Gaston

    2014-01-01

    Minimal Massive Gravity (MMG) is an extension of three-dimensional Topologically Massive Gravity that, when formulated about Anti-de Sitter space, accomplishes to solve the tension between bulk and boundary unitarity that other models in three dimensions suffer from. We study this theory at the chiral point, i.e. at the point of the parameter space where one of the central charges of the dual conformal field theory vanishes. We investigate the non-linear regime of the theory, meaning that we study exact solutions to the MMG field equations that are not Einstein manifolds. We exhibit a large class of solutions of this type, which behave asymptotically in different manners. In particular, we find analytic solutions that represent two-parameter deformations of extremal Banados-Teitelboim-Zanelli (BTZ) black holes. These geometries behave asymptotically as solutions of the so-called Log Gravity, and, despite the weakened falling-off close to the boundary, they have finite mass and finite angular momentum, which w...

  19. Minimal dilaton model

    Directory of Open Access Journals (Sweden)

    Oda Kin-ya

    2013-05-01

    Full Text Available Both the ATLAS and CMS experiments at the LHC have reported the observation of the particle of mass around 125 GeV which is consistent to the Standard Model (SM Higgs boson, but with an excess of events beyond the SM expectation in the diphoton decay channel at each of them. There still remains room for a logical possibility that we are not seeing the SM Higgs but something else. Here we introduce the minimal dilaton model in which the LHC signals are explained by an extra singlet scalar of the mass around 125 GeV that slightly mixes with the SM Higgs heavier than 600 GeV. When this scalar has a vacuum expectation value well beyond the electroweak scale, it can be identified as a linearly realized version of a dilaton field. Though the current experimental constraints from the Higgs search disfavors such a region, the singlet scalar model itself still provides a viable alternative to the SM Higgs in interpreting its search results.

  20. Minimal log gravity

    Science.gov (United States)

    Giribet, Gaston; Vásquez, Yerko

    2015-01-01

    Minimal massive gravity (MMG) is an extension of three-dimensional topologically massive gravity that, when formulated about anti-de Sitter space, accomplishes solving the tension between bulk and boundary unitarity that other models in three dimensions suffer from. We study this theory at the chiral point, i.e. at the point of the parameter space where one of the central charges of the dual conformal field theory vanishes. We investigate the nonlinear regime of the theory, meaning that we study exact solutions to the MMG field equations that are not Einstein manifolds. We exhibit a large class of solutions of this type, which behave asymptotically in different manners. In particular, we find analytic solutions that represent two-parameter deformations of extremal Bañados-Teitelboim-Zanelli black holes. These geometries behave asymptotically as solutions of the so-called log gravity, and, despite the weakened falling off close to the boundary, they have finite mass and finite angular momentum, which we compute. We also find time-dependent deformations of Bañados-Teitelboim-Zanelli that obey Brown-Henneaux asymptotic boundary conditions. The existence of such solutions shows that the Birkhoff theorem does not hold in MMG at the chiral point. Other peculiar features of the theory at the chiral point, such as the degeneracy it exhibits in the decoupling limit, are discussed.

  1. Minimal distances between SCFTs

    Energy Technology Data Exchange (ETDEWEB)

    Buican, Matthew [Department of Physics and Astronomy, Rutgers University,Piscataway, NJ 08854 (United States)

    2014-01-28

    We study lower bounds on the minimal distance in theory space between four-dimensional superconformal field theories (SCFTs) connected via broad classes of renormalization group (RG) flows preserving various amounts of supersymmetry (SUSY). For N=1 RG flows, the ultraviolet (UV) and infrared (IR) endpoints of the flow can be parametrically close. On the other hand, for RG flows emanating from a maximally supersymmetric SCFT, the distance to the IR theory cannot be arbitrarily small regardless of the amount of (non-trivial) SUSY preserved along the flow. The case of RG flows from N=2 UV SCFTs is more subtle. We argue that for RG flows preserving the full N=2 SUSY, there are various obstructions to finding examples with parametrically close UV and IR endpoints. Under reasonable assumptions, these obstructions include: unitarity, known bounds on the c central charge derived from associativity of the operator product expansion, and the central charge bounds of Hofman and Maldacena. On the other hand, for RG flows that break N=2→N=1, it is possible to find IR fixed points that are parametrically close to the UV ones. In this case, we argue that if the UV SCFT possesses a single stress tensor, then such RG flows excite of order all the degrees of freedom of the UV theory. Furthermore, if the UV theory has some flavor symmetry, we argue that the UV central charges should not be too large relative to certain parameters in the theory.

  2. Minimal Flavor Violation in the Lepton Sector

    OpenAIRE

    Cirigliano, Vincenzo; Grinstein, Benjamin; Isidori, Gino; Wise, Mark B.

    2005-01-01

    We extend the notion of Minimal Flavor Violation to the lepton sector. We introduce a symmetry principle which allows us to express lepton flavor violation in the charged lepton sector in terms of neutrino masses and mixing angles. We explore the dependence of the rates for flavor changing radiative charged lepton decays (ell(i) -> ell(j) + gamma) and mu-to-e conversion in nuclei on the scales for total lepton number violation, lepton flavor violation and the neutrino masses and mixing angles...

  3. Minimal model for spoof acoustoelastic surface states

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, J., E-mail: jochri@fotonik.dtu.dk; Willatzen, M. [Department of Photonics Engineering, Technical University of Denmark, DK-2800 Kgs. Lyngby (Denmark); Liang, Z. [College of Electronic Science and Technology, Shenzhen University, Shenzhen (China)

    2014-12-15

    Similar to textured perfect electric conductors for electromagnetic waves sustaining artificial or spoof surface plasmons we present an equivalent phenomena for the case of sound. Aided by a minimal model that is able to capture the complex wave interaction of elastic cavity modes and airborne sound radiation in perfect rigid panels, we construct designer acoustoelastic surface waves that are entirely controlled by the geometrical environment. Comparisons to results obtained by full-wave simulations confirm the feasibility of the model and we demonstrate illustrative examples such as resonant transmissions and waveguiding to show a few examples of many where spoof elastic surface waves are useful.

  4. Minimal model for spoof acoustoelastic surface states

    Directory of Open Access Journals (Sweden)

    J. Christensen

    2014-12-01

    Full Text Available Similar to textured perfect electric conductors for electromagnetic waves sustaining artificial or spoof surface plasmons we present an equivalent phenomena for the case of sound. Aided by a minimal model that is able to capture the complex wave interaction of elastic cavity modes and airborne sound radiation in perfect rigid panels, we construct designer acoustoelastic surface waves that are entirely controlled by the geometrical environment. Comparisons to results obtained by full-wave simulations confirm the feasibility of the model and we demonstrate illustrative examples such as resonant transmissions and waveguiding to show a few examples of many where spoof elastic surface waves are useful.

  5. Minimal model for spoof acoustoelastic surface states

    DEFF Research Database (Denmark)

    Christensen, Johan; Liang, Z.; Willatzen, Morten

    2014-01-01

    Similar to textured perfect electric conductors for electromagnetic waves sustaining artificial or spoof surface plasmons we present an equivalent phenomena for the case of sound. Aided by a minimal model that is able to capture the complex wave interaction of elastic cavity modes and airborne...... sound radiation in perfect rigid panels, we construct designer acoustoelastic surface waves that are entirely controlled by the geometrical environment. Comparisons to results obtained by full-wave simu- lations confirm the feasibility of the model and we demonstrate illustrative examples...

  6. Radiation Protection

    Science.gov (United States)

    ... EPA United States Environmental Protection Agency Search Search Radiation Protection Share Facebook Twitter Google+ Pinterest Contact Us Radiation Protection Document Library View and download EPA radiation ...

  7. On stable compact minimal submanifolds

    CERN Document Server

    Torralbo, Francisco

    2010-01-01

    Stable compact minimal submanifolds of the product of a sphere and any Riemannian manifold are classified whenever the dimension of the sphere is at least three. The complete classification of the stable compact minimal submanifolds of the product of two spheres is obtained. Also, it is proved that the only stable compact minimal surfaces of the product of a 2-sphere and any Riemann surface are the complex ones.

  8. Efficacy of Combined Endoscopic Lithotomy and Extracorporeal Shock Wave Lithotripsy, and Additional Electrohydraulic Lithotripsy Using the SpyGlass Direct Visualization System or X-Ray Guided EHL as Needed, for Pancreatic Lithiasis

    Directory of Open Access Journals (Sweden)

    Ken Ito

    2014-01-01

    Full Text Available Introduction. To evaluate the efficacy of combined endoscopic lithotomy and extracorporeal shock wave lithotripsy (ESWL, and additional electrohydraulic lithotripsy (EHL as needed, for the treatment of pancreatic duct stones, we retrospectively evaluated 98 patients with chronic pancreatitis and pancreatic lithiasis. Methods. For the management of main pancreatic duct (MPD stones in 98 patients, we performed combined endoscopic treatment (ET/ESWL therapy as the first treatment option. When combined ET/ESWL was unsuccessful, EHL with the SpyGlass Direct Visualization system or X-ray guided EHL was performed. Outpatient ESWL was reserved as one of the final treatment options. Results. Fragmentation was successful in 80 (81.6% patients as follows: combined ET/ESWL: 67 cases; SpyGlass EHL: 4 cases; X-ray guided EHL: 3 cases; and outpatient ESWL: 6 cases. Successful outcome was obtained by combined ET/ESWL in 67 of the 98 patients (74.5%, by EHL in 7 of 14 patients (7.1%, and by outpatient ESWL in 6 of 6 patients (6.1%. Negotiating the guidewire through a severe MPD stricture was significantly associated with a higher rate of stone fragmentation (P=0.0003. Conclusions. In cases where combined ET/ESWL was not successful for stone clearance, EHL using the SpyGlass system or X-ray guided EHL was effective in cases where the guidewire could be negotiated through the MPD stricture and it increased the fragmentation rate.

  9. Global Analysis of Minimal Surfaces

    CERN Document Server

    Dierkes, Ulrich; Tromba, Anthony J

    2010-01-01

    Many properties of minimal surfaces are of a global nature, and this is already true for the results treated in the first two volumes of the treatise. Part I of the present book can be viewed as an extension of these results. For instance, the first two chapters deal with existence, regularity and uniqueness theorems for minimal surfaces with partially free boundaries. Here one of the main features is the possibility of 'edge-crawling' along free parts of the boundary. The third chapter deals with a priori estimates for minimal surfaces in higher dimensions and for minimizers of singular integ

  10. Minimal surfaces for architectural constructions

    Directory of Open Access Journals (Sweden)

    Velimirović Ljubica S.

    2008-01-01

    Full Text Available Minimal surfaces are the surfaces of the smallest area spanned by a given boundary. The equivalent is the definition that it is the surface of vanishing mean curvature. Minimal surface theory is rapidly developed at recent time. Many new examples are constructed and old altered. Minimal area property makes this surface suitable for application in architecture. The main reasons for application are: weight and amount of material are reduced on minimum. Famous architects like Otto Frei created this new trend in architecture. In recent years it becomes possible to enlarge the family of minimal surfaces by constructing new surfaces.

  11. On minimal artinian modules and minimal artinian linear groups

    Directory of Open Access Journals (Sweden)

    Leonid A. Kurdachenko

    2001-01-01

    minimal artinian linear groups. The authors prove that in such classes of groups as hypercentral groups (so also, nilpotent and abelian groups and FC-groups, minimal artinian linear groups have precisely the same structure as the corresponding irreducible linear groups.

  12. Minimally invasive local therapies for liver cancer

    Institute of Scientific and Technical Information of China (English)

    David Li; Josephine Kang; Benjamin J Golas; Vincent W Yeung; David C Madoff

    2014-01-01

    Primary and metastatic liver tumors are an increasing global health problem, with hepatocellular carcinoma (HCC) now being the third leading cause of cancer-related mortality worldwide. Systemic treatment options for HCC remain limited, with Sorafenib as the only prospectively validated agent shown to increase overall survival. Surgical resection and/or transplantation, locally ablative therapies and regional or locoregional therapies have iflled the gap in liver tumor treatments, providing improved survival outcomes for both primary and metastatic tumors. Minimally invasive local therapies have an increasing role in the treatment of both primary and metastatic liver tumors. For patients with low volume disease, these therapies have now been established into consensus practice guidelines. This review highlights technical aspects and outcomes of commonly utilized, minimally invasive local therapies including laparoscopic liver resection (LLR), radiofrequency ablation (RFA), microwave ablation (MWA), high-intensity focused ultrasound (HIFU), irreversible electroporation (IRE), and stereotactic body radiation therapy (SBRT). In addition, the role of combination treatment strategies utilizing these minimally invasive techniques is reviewed.

  13. Radiation Therapy

    Science.gov (United States)

    ... the area is stitched shut. Another treatment, called proton-beam radiation therapy , focuses the radiation on the ... after radiation treatment ends. Sore mouth and tooth decay. If you received radiation therapy to the head ...

  14. Radiation sickness

    Science.gov (United States)

    ... radiation. There are two basic types of radiation: ionizing and nonionizing. Nonionizing radiation comes in the form of light, radio waves, microwaves and radar. This kind of radiation usually ...

  15. Minimal massive 3D gravity

    NARCIS (Netherlands)

    Bergshoeff, Eric; Hohm, Olaf; Merbis, Wout; Routh, Alasdair J.; Townsend, Paul K.

    2014-01-01

    We present an alternative to topologically massive gravity (TMG) with the same 'minimal' bulk properties; i.e. a single local degree of freedom that is realized as a massive graviton in linearization about an anti-de Sitter (AdS) vacuum. However, in contrast to TMG, the new 'minimal massive gravity'

  16. Uniqueness of PL Minimal Surfaces

    Institute of Scientific and Technical Information of China (English)

    Yi NI

    2007-01-01

    Using a standard fact in hyperbolic geometry, we give a simple proof of the uniqueness of PL minimal surfaces, thus filling in a gap in the original proof of Jaco and Rubinstein. Moreover, in order to clarify some ambiguity, we sharpen the definition of PL minimal surfaces, and prove a technical lemma on the Plateau problem in the hyperbolic space.

  17. Guidelines for mixed waste minimization

    Energy Technology Data Exchange (ETDEWEB)

    Owens, C.

    1992-02-01

    Currently, there is no commercial mixed waste disposal available in the United States. Storage and treatment for commercial mixed waste is limited. Host States and compacts region officials are encouraging their mixed waste generators to minimize their mixed wastes because of management limitations. This document provides a guide to mixed waste minimization.

  18. Influenza SIRS with Minimal Pneumonitis.

    Science.gov (United States)

    Erramilli, Shruti; Mannam, Praveen; Manthous, Constantine A

    2016-01-01

    Although systemic inflammatory response syndrome (SIRS) is a known complication of severe influenza pneumonia, it has been reported very rarely in patients with minimal parenchymal lung disease. We here report a case of severe SIRS, anasarca, and marked vascular phenomena with minimal or no pneumonitis. This case highlights that viruses, including influenza, may cause vascular dysregulation causing SIRS, even without substantial visceral organ involvement.

  19. Minimal changes in health status questionnaires: distinction between minimally detectable change and minimally important change

    Directory of Open Access Journals (Sweden)

    Knol Dirk L

    2006-08-01

    Full Text Available Abstract Changes in scores on health status questionnaires are difficult to interpret. Several methods to determine minimally important changes (MICs have been proposed which can broadly be divided in distribution-based and anchor-based methods. Comparisons of these methods have led to insight into essential differences between these approaches. Some authors have tried to come to a uniform measure for the MIC, such as 0.5 standard deviation and the value of one standard error of measurement (SEM. Others have emphasized the diversity of MIC values, depending on the type of anchor, the definition of minimal importance on the anchor, and characteristics of the disease under study. A closer look makes clear that some distribution-based methods have been merely focused on minimally detectable changes. For assessing minimally important changes, anchor-based methods are preferred, as they include a definition of what is minimally important. Acknowledging the distinction between minimally detectable and minimally important changes is useful, not only to avoid confusion among MIC methods, but also to gain information on two important benchmarks on the scale of a health status measurement instrument. Appreciating the distinction, it becomes possible to judge whether the minimally detectable change of a measurement instrument is sufficiently small to detect minimally important changes.

  20. Radiation dosimetry.

    OpenAIRE

    Cameron, J

    1991-01-01

    This article summarizes the basic facts about the measurement of ionizing radiation, usually referred to as radiation dosimetry. The article defines the common radiation quantities and units; gives typical levels of natural radiation and medical exposures; and describes the most important biological effects of radiation and the methods used to measure radiation. Finally, a proposal is made for a new radiation risk unit to make radiation risks more understandable to nonspecialists.

  1. Minimal Webs in Riemannian Manifolds

    DEFF Research Database (Denmark)

    Markvorsen, Steen

    2008-01-01

    are of instrumental importance for the applications. We apply these properties to show that minimal webs in ambient Riemannian spaces share several analytic and geometric properties with their smooth (minimal submanifold) counterparts in such spaces. In particular we use appropriate versions of the divergence......)$ into Riemannian manifolds $(N^{n}, h)$. Such immersions we call {\\em{minimal webs}}. They admit a natural 'geometric' extension of the intrinsic combinatorial discrete Laplacian. The geometric Laplacian on minimal webs enjoys standard properties such as the maximum principle and the divergence theorems, which...... theorems together with the comparison techniques for distance functions in Riemannian geometry and obtain bounds for the first Dirichlet eigenvalues, the exit times and the capacities as well as isoperimetric type inequalities for so-called extrinsic $R-$webs of minimal webs in ambient Riemannian manifolds...

  2. Waste minimization handbook, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Boing, L.E.; Coffey, M.J.

    1995-12-01

    This technical guide presents various methods used by industry to minimize low-level radioactive waste (LLW) generated during decommissioning and decontamination (D and D) activities. Such activities generate significant amounts of LLW during their operations. Waste minimization refers to any measure, procedure, or technique that reduces the amount of waste generated during a specific operation or project. Preventive waste minimization techniques implemented when a project is initiated can significantly reduce waste. Techniques implemented during decontamination activities reduce the cost of decommissioning. The application of waste minimization techniques is not limited to D and D activities; it is also useful during any phase of a facility`s life cycle. This compendium will be supplemented with a second volume of abstracts of hundreds of papers related to minimizing low-level nuclear waste. This second volume is expected to be released in late 1996.

  3. Radiative breaking of the minimal supersymmetric left–right model

    Directory of Open Access Journals (Sweden)

    Nobuchika Okada

    2016-05-01

    Full Text Available We study a variation to the SUSY Left–Right symmetric model based on the gauge group SU(3c×SU(2L×SU(2R×U(1BL. Beyond the quark and lepton superfields we only introduce a second Higgs bidoublet to produce realistic fermion mass matrices. This model does not include any SU(2R triplets. We calculate renormalization group evolutions of soft SUSY parameters at the one-loop level down to low energy. We find that an SU(2R slepton doublet acquires a negative mass squared at low energies, so that the breaking of SU(2R×U(1BL→U(1Y is realized by a non-zero vacuum expectation value of a right-handed sneutrino. Small neutrino masses are produced through neutrino mixings with gauginos. Mass limits on the SU(2R×U(1BL sector are obtained by direct search results at the LHC as well as lepton-gaugino mixing bounds from the LEP precision data.

  4. Radiative Breaking of the Minimal Supersymmetric Left-Right Model

    CERN Document Server

    Okada, Nobuchika

    2016-01-01

    We propose a new variation to the SUSY Left-Right symmetric model based on the gauge group $SU(3)_c\\times SU(2)_L\\times SU(2)_R\\times U(1)_{BL}$. Beyond the quark and lepton superfields we only introduce a second Higgs bidoublet to produce realistic fermion mass matrices. This model does not include any $SU(2)_R$ triplets. We calculate renormalization group evolutions of soft SUSY parameters at the one-loop level down to low energy. We find that an $SU(2)_R$ slepton doublet acquires a negative mass squared at low energies, so that the breaking of $SU(2)_R\\times U(1)_{BL}\\rightarrow U(1)_Y$ is realized by a non-zero vacuum expectation value of a right-handed sneutrino. Small neutrino masses are produced through neutrino mixings with gauginos. Mass limits on the $SU(2)_R\\times U(1)_{BL}$ sector are obtained by direct search results at the LHC as well as lepton-gaugino mixing bounds from the LEP precision data.

  5. Microbiological, physicochemical and sensory evaluation of cabbage and carrot minimally processed salad after radiation treatment intended to immunocompromised patients or with special diets; Avaliacao microbiologica, fisico-quimica e sensorial de salada de repolho com cenoura minimamente processada apos o tratamento por radiacao gama destinado a pacientes imunocomprometidos ou com dietas especiais

    Energy Technology Data Exchange (ETDEWEB)

    Nunes, Thaise Cristine Fernandes

    2015-09-01

    During and after the treatment of cancer, people with HIV or transplants, the food intake can offer a well-being to the patient, because the action of eating right helps people to feel strong. Healthy people have their immune system working properly and can tolerate small amounts of bacteria. However, immunocompromised persons may not be able to and however immunocompromised people cannot fight this small amount of microorganisms and require a diet with very low microbiological count to avoid contact with potentially harmful bacteria. This is called neutropenic diet. These patients are susceptible to food contamination, so that it's not advisable the ingestion of raw products. The vegetable irradiation with low doses has the purpose of reducing the microbial load. The aim of this study was to obtain data on microbiological, sensorial e physicochemical aspects in minimally processed 'Primavera' salad irradiated with different doses of gamma radiation designed to immunocompromised patients. It were used doses of 1.0kGy, 2.0kGy, 3.0kGy and 4.0kGy irradiated in the Multipurpose Irradiator {sup 60}Co located in Radiation Technology Center. Microbiological analyzes were performed (n=25) using Petrifilm, sensory analysis using the sensory acceptance test (n=30) and triangular (n=15) and texture analysis (n=90) in the Food Microbiology Laboratory located at the Radiation Technology Center. The texture analysis was performed with the aid of a texturometer equipped with 5 kg load cell using a triangular cutting Warner-Bratzler Knife blade probe with the descent speed of 2mm/sec. All results were expressed in Newtons (N). The results showed that for microbiological analyzes the standards were followed according to the RDC 12/01 ANVISA. For the sensory test of acceptation no difference was found among the samples, however in the triangular test could be found slight differences between samples irradiated with 4.0kGy and control and there was significant

  6. EXPERIENCE OF ORGANIZING OF THE RADIATION SITUATION MONITORING, DEVELOPMENT AND IMPLEMENTATION OF MEASURES TO MINIMIZE RISKS OF RADIATION EXPOSURE OF THE MAGADAN REGION POPULATION RELATED TO THE FUKUSHIMA ACCIDENT BY THE ADMINISTRATION OF THE FEDERAL SERVICE FOR SURVEILLANCE ON CONSUMER RIGHTS PROTECTION AND HUMAN WELL-BEING IN MAGADAN REGION AND FEDERAL HEALTH ORGANIZATION "CENTER OF HYGIENE AND EPIDEMIOLOGY IN MAGADAN REGION"

    Directory of Open Access Journals (Sweden)

    A. A. Rubtsova

    2011-01-01

    Full Text Available The article presents results of activities of the Administration of the Federal Service for Surveillance on Consumer Rights Protection and Human Well-being in Magadan region and the Federal Health Organization "Center of Hygiene and Epidemiology in Magadan region" in the context of monitoring of the radiation situation in the Magadan region from 12.03.2011 in connection with the Fukushima accident in Japan. The authors present the data on radiological laboratory studies, the analysis of performed organizational activities, the results of co-operation with the state and other regulatory authorities.

  7. Superspace geometry and the minimal, non minimal, and new minimal supergravity multiplets

    Energy Technology Data Exchange (ETDEWEB)

    Girardi, G.; Grimm, R.; Mueller, M.; Wess, J.

    1984-11-01

    We analyse superspace constraints in a systematic way and define a set of natural constraints. We give a complete solution of the Bianchi identities subject to these constraints and obtain a reducible, but not fully reducible multiplet. By additional constraints it can be reduced to either the minimal nonminimal or new minimal multiplet. We discuss the superspace actions for the various multiplets.

  8. Locally minimal topological groups 1

    OpenAIRE

    Chasco, María Jesús; Dikranjan, Dikran N.; Außenhofer, Lydia; Domínguez, Xabier

    2015-01-01

    The aim of this paper is to go deeper into the study of local minimality and its connection to some naturally related properties. A Hausdorff topological group ▫$(G,tau)$▫ is called locally minimal if there exists a neighborhood ▫$U$▫ of 0 in ▫$tau$▫ such that ▫$U$▫ fails to be a neighborhood of zero in any Hausdorff group topology on ▫$G$▫ which is strictly coarser than ▫$tau$▫. Examples of locally minimal groups are all subgroups of Banach-Lie groups, all locally compact groups and all mini...

  9. Minimal flows and their extensions

    CERN Document Server

    Auslander, J

    1988-01-01

    This monograph presents developments in the abstract theory of topological dynamics, concentrating on the internal structure of minimal flows (actions of groups on compact Hausdorff spaces for which every orbit is dense) and their homomorphisms (continuous equivariant maps). Various classes of minimal flows (equicontinuous, distal, point distal) are intensively studied, and a general structure theorem is obtained. Another theme is the ``universal'' approach - entire classes of minimal flows are studied, rather than flows in isolation. This leads to the consideration of disjointness of flows, w

  10. 超声引导下经皮肾镜钬激光碎石术治疗孤立肾上尿路结石%Percutaneous Nephrolithotripsy with Holmium Laser Under Ultrasound Guidance for 23 Patients with Upper Urinary Tract Lithiasis of Solitary kidney

    Institute of Scientific and Technical Information of China (English)

    柳懿鹏; 章传华; 袁敬东

    2013-01-01

    [Objective]To explore the efficacy of percutaneous nephrolithotripsy with holmium laser under ultrasound guidance for the treatment of upper urinary tract lithiasis of solitary kidney.[Methods]From Aug.2010 to Nov.2012,a total of 23 patients with upper urinary tract lithiasis of solitary kidney underwent percutaneous nephrolithotripsy with holmium laser under ultrasound guidance.[Results]Among 23 patients,20 patients(87%) were stone-free after operation.Mean hospital stay was 7.1 days(ranging from 4 to 16 days).Of 16 patients with kidney insufficiency,renal function of 14 patients recovered the normal after operation.Compared with before operation,serum creatinine of 2 patients obviously decreased.No hemorrhea occurred.[Conclusion] Percutaneous nephrolithotripsy with holmium laser under ultrasound guidance for the treatment of upper urinary tract lithiasis of solitary kidney is effective and safe.%[目的]探讨超声引导下经皮肾镜碎石术治疗孤立肾上尿路结石的疗效.[方法]2010年8月至2012年11月,对23例孤立肾上尿路结石患者采用在超声引导下经皮肾镜钬激光碎石术治疗.[结果]23例患者中有20例术后复查无结石残留,平均住院时间7.1(4~16)d,16例肾功能不全患者中,术后14例肾功能恢复正常,2例血肌酐较术前明显下降,无大出血发生.[结论]超声引导下经皮肾镜钬激光碎石术治疗孤立肾上尿路结石安全有效.

  11. Sludge minimization technologies - an overview

    Energy Technology Data Exchange (ETDEWEB)

    Oedegaard, Hallvard

    2003-07-01

    The management of wastewater sludge from wastewater treatment plants represents one of the major challenges in wastewater treatment today. The cost of the sludge treatment amounts to more that the cost of the liquid in many cases. Therefore the focus on and interest in sludge minimization is steadily increasing. In the paper an overview is given for sludge minimization (sludge mass reduction) options. It is demonstrated that sludge minimization may be a result of reduced production of sludge and/or disintegration processes that may take place both in the wastewater treatment stage and in the sludge stage. Various sludge disintegration technologies for sludge minimization are discussed, including mechanical methods (focusing on stirred ball-mill, high-pressure homogenizer, ultrasonic disintegrator), chemical methods (focusing on the use of ozone), physical methods (focusing on thermal and thermal/chemical hydrolysis) and biological methods (focusing on enzymatic processes). (author)

  12. Minimally invasive surgery. Future developments.

    OpenAIRE

    1994-01-01

    The rapid development of minimally invasive surgery means that there will be fundamental changes in interventional treatment. Technological advances will allow new minimally invasive procedures to be developed. Application of robotics will allow some procedures to be done automatically, and coupling of slave robotic instruments with virtual reality images will allow surgeons to perform operations by remote control. Miniature motors and instruments designed by microengineering could be introdu...

  13. Cost minimization and asset pricing

    OpenAIRE

    Robert G. Chambers; John Quiggin

    2005-01-01

    A cost-based approach to asset-pricing equilibrium relationships is developed. A cost function induces a stochastic discount factor (pricing kernel) that is a function of random output, prices, and capital stockt. By eliminating opportunities for arbitrage between financial markets and the production technology, firms minimize the current cost of future consumption. The first-order conditions for this cost minimization problem generate the stochastic discount factor. The cost-based approach i...

  14. Influenza SIRS with minimal pneumonitis

    Directory of Open Access Journals (Sweden)

    Shruti Erramilli

    2016-08-01

    Full Text Available While systemic inflammatory response syndrome (SIRS, is a known complication of severe influenza pneumonia, it has been reported very rarely in patients with minimal parenchymal lung disease. We here report a case of severe SIRS, anasarca and marked vascular phenomena with minimal or no pneumonitis. This case highlights that viruses, including influenza, may cause vascular dysregulation causing SIRS, even without substantial visceral organ involvement.

  15. Radiation synovectomy revisited

    Energy Technology Data Exchange (ETDEWEB)

    Deutsch, E. (Mallinckrodt Medical, Inc., St. Louis, MO (United States)); Brodack, J.W. (Mallinckrodt Medical, Inc., St. Louis, MO (United States)); Deutsch, K.F. (Mallinckrodt Medical, Inc., St. Louis, MO (United States))

    1993-11-01

    Radiation synovectomy is a potential weapon in the therapeutic armamentarium of nuclear medicine. It is an attractive alternative to surgical or chemical synovectomy for the treatment of rheumatoid arthritis. In this article the clinical results obtained with radiation synovectomy from the 1950s through 1992 are summarized and reviewed. Even after taking into account the paucity of well-controlled trials and rigorous clinical follow-up, it is clear that radiation synovectomy is efficacious in controlling the symptoms of rheumatoid arthritis. However, the procedure is not widely used because of concerns about leakage of radioactivity from the treated joint, and the resulting high doses that can be delivated to nontarget organs. New approaches to the preparation of radiolabeled particles for use in radiation synovectomy promise to minimize this leakage and thus allows the full potential of this important radiotherapy to be realized. (orig.)

  16. The minimal curvaton-Higgs model

    Energy Technology Data Exchange (ETDEWEB)

    Enqvist, Kari [Helsinki Univ. and Helsinki Institute of Physics (Finland). Physics Dept.; Lerner, Rose N. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Helsinki Univ. and Helsinki Institute of Physics (Finland). Physics Dept.; Takahashi, Tomo [Saga Univ. (Japan). Dept. of Physics

    2013-10-15

    We present the first full study of the minimal curvaton-Higgs (MCH) model, which is a minimal interpretation of the curvaton scenario with one real scalar coupled to the standard model Higgs boson. The standard model coupling allows the dynamics of the model to be determined in detail, including effects from the thermal background and from radiative corrections to the potential. The relevant mechanisms for curvaton decay are incomplete non-perturbative decay (delayed by thermal blocking), followed by decay via a dimension-5 non-renormalisable operator. To avoid spoiling the predictions of big bang nucleosynthesis, we find the ''bare'' curvaton mass to be m{sub {sigma}}{>=}8 x 10{sup 4} GeV. To match observational data from Planck there is an upper limit on the curvaton-higgs coupling g, between 10{sup -3} and 10{sup -2}, depending on the mass. This is due to interactions with the thermal background. We find that typically non-Gaussianities are small but that if f{sub NL} is observed in the near future then m{sub {sigma}}

  17. Radiation Therapy

    Science.gov (United States)

    Radiation therapy is a cancer treatment. It uses high doses of radiation to kill cancer cells and stop them from ... half of all cancer patients receive it. The radiation may be external, from special machines, or internal, ...

  18. Radiation dosimetry

    CERN Document Server

    Hine, Gerald J; Hine, Gerald J

    1956-01-01

    Radiation Dosimetry focuses on the advancements, processes, technologies, techniques, and principles involved in radiation dosimetry, including counters and calibration and standardization techniques. The selection first offers information on radiation units and the theory of ionization dosimetry and interaction of radiation with matter. Topics include quantities derivable from roentgens, determination of dose in roentgens, ionization dosimetry of high-energy photons and corpuscular radiations, and heavy charged particles. The text then examines the biological and medical effects of radiation,

  19. Minimally Invasive Spinal Surgery with Intraoperative Image-Guided Navigation

    Directory of Open Access Journals (Sweden)

    Terrence T. Kim

    2016-01-01

    Full Text Available We present our perioperative minimally invasive spine surgery technique using intraoperative computed tomography image-guided navigation for the treatment of various lumbar spine pathologies. We present an illustrative case of a patient undergoing minimally invasive percutaneous posterior spinal fusion assisted by the O-arm system with navigation. We discuss the literature and the advantages of the technique over fluoroscopic imaging methods: lower occupational radiation exposure for operative room personnel, reduced need for postoperative imaging, and decreased revision rates. Most importantly, we demonstrate that use of intraoperative cone beam CT image-guided navigation has been reported to increase accuracy.

  20. Minimally Invasive Video-Assisted versus Minimally Invasive Nonendoscopic Thyroidectomy

    Directory of Open Access Journals (Sweden)

    Zdeněk Fík

    2014-01-01

    Full Text Available Minimally invasive video-assisted thyroidectomy (MIVAT and minimally invasive nonendoscopic thyroidectomy (MINET represent well accepted and reproducible techniques developed with the main goal to improve cosmetic outcome, accelerate healing, and increase patient’s comfort following thyroid surgery. Between 2007 and 2011, a prospective nonrandomized study of patients undergoing minimally invasive thyroid surgery was performed to compare advantages and disadvantages of the two different techniques. There were no significant differences in the length of incision to perform surgical procedures. Mean duration of hemithyroidectomy was comparable in both groups, but it was more time consuming to perform total thyroidectomy by MIVAT. There were more patients undergoing MIVAT procedures without active drainage in the postoperative course and we also could see a trend for less pain in the same group. This was paralleled by statistically significant decreased administration of both opiates and nonopiate analgesics. We encountered two cases of recurrent laryngeal nerve palsies in the MIVAT group only. MIVAT and MINET represent safe and feasible alternative to conventional thyroid surgery in selected cases and this prospective study has shown minimal differences between these two techniques.

  1. Minimizing Costs Can Be Costly

    Directory of Open Access Journals (Sweden)

    Rasmus Rasmussen

    2010-01-01

    Full Text Available A quite common practice, even in academic literature, is to simplify a decision problem and model it as a cost-minimizing problem. In fact, some type of models has been standardized to minimization problems, like Quadratic Assignment Problems (QAPs, where a maximization formulation would be treated as a “generalized” QAP and not solvable by many of the specially designed softwares for QAP. Ignoring revenues when modeling a decision problem works only if costs can be separated from the decisions influencing revenues. More often than we think this is not the case, and minimizing costs will not lead to maximized profit. This will be demonstrated using spreadsheets to solve a small example. The example is also used to demonstrate other pitfalls in network models: the inability to generally balance the problem or allocate costs in advance, and the tendency to anticipate a specific type of solution and thereby make constraints too limiting when formulating the problem.

  2. Minimal Marking: A Success Story

    Directory of Open Access Journals (Sweden)

    Anne McNeilly

    2014-11-01

    Full Text Available The minimal-marking project conducted in Ryerson’s School of Journalism throughout 2012 and early 2013 resulted in significantly higher grammar scores in two first-year classes of minimally marked university students when compared to two traditionally marked classes. The “minimal-marking” concept (Haswell, 1983, which requires dramatically more student engagement, resulted in more successful learning outcomes for surface-level knowledge acquisition than the more traditional approach of “teacher-corrects-all.” Results suggest it would be effective, not just for grammar, punctuation, and word usage, the objective here, but for any material that requires rote-memory learning, such as the Associated Press or Canadian Press style rules used by news publications across North America.

  3. Radiative plateau inflation

    CERN Document Server

    Ballesteros, Guillermo

    2016-01-01

    We describe how monomial chaotic inflation becomes compatible with the latest CMB data thanks to radiative corrections producing a plateau. The interactions of the inflation with other fields, required for reheating, can flatten the potential and moderate the production of primordial gravitational waves, keeping these below the current upper bound. We show that the appearance of a plateau requires that the inflaton couples to fermions and to another scalar or a gauge group. We give concrete examples of minimal particle physics models leading to plateaus for quadratic and quartic chaotic inflation. We also provide a three-parameter model-independent description of radiatively corrected inflation that is amenable to CMB analyses.

  4. Absorbed Power Minimization in Cellular Users with Circular Antenna Arrays

    Science.gov (United States)

    Christofilakis, Vasilis; Votis, Constantinos; Tatsis, Giorgos; Raptis, Vasilis; Kostarakis, Panos

    2010-01-01

    Nowadays electromagnetic pollution of non ionizing radiation generated by cellular phones concerns millions of people. In this paper the use of circular antenna array as a means of minimizing the absorbed power by cellular phone users is introduced. In particular, the different characteristics of radiation patterns produced by a helical conventional antenna used in mobile phones operating at 900 MHz and those produced by a circular antenna array, hypothetically used in the same mobile phones, are in detail examined. Furthermore, the percentage of decrement of the power absorbed in the head as a function of direction of arrival is estimated for the circular antenna array.

  5. Minimal Flavor Constraints for Technicolor

    DEFF Research Database (Denmark)

    Sakuma, Hidenori; Sannino, Francesco

    2010-01-01

    We analyze the constraints on the the vacuum polarization of the standard model gauge bosons from a minimal set of flavor observables valid for a general class of models of dynamical electroweak symmetry breaking. We will show that the constraints have a strong impact on the self-coupling and mas...

  6. Dubin's Minimal Linkage Construct Revisited.

    Science.gov (United States)

    Rogers, Donald P.

    This paper contains a theoretical analysis and empirical study that support the major premise of Robert Dubin's minimal-linkage construct-that restricting communication links increases organizational stability. The theoretical analysis shows that fewer communication links are associated with less uncertainty, more redundancy, and greater…

  7. Minimal Surfaces for Hitchin Representations

    DEFF Research Database (Denmark)

    Li, Qiongling; Dai, Song

    2016-01-01

    Given a reductive representation $\\rho: \\pi_1(S)\\rightarrow G$, there exists a $\\rho$-equivariant harmonic map $f$ from the universal cover of a fixed Riemann surface $\\Sigma$ to the symmetric space $G/K$ associated to $G$. If the Hopf differential of $f$ vanishes, the harmonic map is then minimal...

  8. Acquiring minimally invasive surgical skills

    NARCIS (Netherlands)

    Hiemstra, Ellen

    2012-01-01

    Many topics in surgical skills education have been implemented without a solid scientific basis. For that reason we have tried to find this scientific basis. We have focused on training and evaluation of minimally invasive surgical skills in a training setting and in practice in the operating room.

  9. What is minimally invasive dentistry?

    Science.gov (United States)

    Ericson, Dan

    2004-01-01

    Minimally Invasive Dentistry is the application of "a systematic respect for the original tissue." This implies that the dental profession recognizes that an artifact is of less biological value than the original healthy tissue. Minimally invasive dentistry is a concept that can embrace all aspects of the profession. The common delineator is tissue preservation, preferably by preventing disease from occurring and intercepting its progress, but also removing and replacing with as little tissue loss as possible. It does not suggest that we make small fillings to restore incipient lesions or surgically remove impacted third molars without symptoms as routine procedures. The introduction of predictable adhesive technologies has led to a giant leap in interest in minimally invasive dentistry. The concept bridges the traditional gap between prevention and surgical procedures, which is just what dentistry needs today. The evidence-base for survival of restorations clearly indicates that restoring teeth is a temporary palliative measure that is doomed to fail if the disease that caused the condition is not addressed properly. Today, the means, motives and opportunities for minimally invasive dentistry are at hand, but incentives are definitely lacking. Patients and third parties seem to be convinced that the only things that count are replacements. Namely, they are prepared to pay for a filling but not for a procedure that can help avoid having one.

  10. On Minimal Norms on Mn

    Directory of Open Access Journals (Sweden)

    Madjid Mirzavaziri

    2007-01-01

    norms ‖⋅‖1 and ‖⋅‖2 on ℂn such that N(A=max{‖Ax‖2:‖x‖1=1, x∈ℂn} for all A∈ℳn. This may be regarded as an extension of a known result on characterization of minimal algebra norms.

  11. Implications of minimally invasive therapy

    NARCIS (Netherlands)

    Banta, H.D.; Schersten, T.; Jonsson, E.

    1993-01-01

    The field of minimally invasive therapy (MIT) raises many important issues for the future of health care. It seems inevitable that MIT will replace much conventional surgery. This trend is good for society and good for patients. The health care system, however, may find the change disruptive. The

  12. Radiation protection

    CERN Document Server

    CERN. Geneva

    2001-01-01

    This will be a simple explanation of the reasons why CERN has to be careful about radiation protections issues, a practical guide on how to recognize radiation dangers, the monitoring systems that make sure radiation levels are well tolerable norms, and a quick summary of what radiation levels mean in terms of personal risk.

  13. Implications of the Higgs discovery on minimal dark matter

    CERN Document Server

    Klasen, M

    2014-01-01

    The existence of dark matter provides compelling evidence for physics beyond the Standard Model. Minimal extensions of the Standard Model with additional scalars or fermions allow to explain the observed dark matter relic density in an economic way. We analyse several of these possibilities like the inert Higgs and radiative seesaw models in the light of the recent Higgs discovery and study prospects for the direct and indirect detection of dark matter in these models.

  14. Reheating temperature in non-minimal derivative coupling model

    CERN Document Server

    Sadjadi, H Mohseni

    2013-01-01

    We consider the inflaton as a scalar field described by a non-minimal derivative coupling model with a power law potential. We study the slow roll inflation, the rapid oscillation phase, the radiation dominated and the recombination eras respectively, and estimate e-folds numbers during these epochs. Using these results we determine the reheating temperature in terms of the spectral index and the amplitude of the power spectrum of scalar perturbations.

  15. Clinical Observation on Electroacupuncture Combined with Chinese Medicine for the Treatment of Asymptomatic Hepatolithiasis Lithiasis%电针配合中药治疗无症状肝内胆管结石的临床观察

    Institute of Scientific and Technical Information of China (English)

    刁永红; 刘文娟; 马华; 吕美珍; 张新慧

    2014-01-01

    目的:观察电针配合中药治疗无症状肝内胆管结石的疗效。方法:将查体发现的60例无症状肝内胆管结石患者随机分为两组,治疗组电针加中药治疗,口服中成药:胆舒软胶囊,2粒/次,3次/天,电针取穴:期门(右)、日月(右)、阳陵泉、支沟,电针治疗60 min;对照组仅口服胆舒软胶囊,用法同上。结果:治疗组排石率为86.7%,对照组排石率为63.3%,差异有显著性意义( P<0.05);彩超结果比较,治疗组总有效率为83.3%,优于对照组66.7%。结论:电针配合中药治疗无症状肝内胆管结石疗效肯定,较单用中药治疗有明显优势。%Objective:To observe the electroacupuncture and Chinse medicine for the treatment of asymptomat-ic hepatolithiasis lithiasis.Methods:60 patients with asymptomatic hepatolithiasis were divided randomly into two groups.Acupoints of the treatment group:Qimen( right) , Riyue( right) , Yanglingquan, Zhigou.60 minutes electroacupunture was given to the patients in the treatment group, and Danshu soft capsules were given to two groups in the dose of 2 capsules, 3 times a day.Results:The rate of stone expulsion was 86.7% in the treat-ment group and 63.3%in the control group with a significant difference between two groups (P<0.05).Ac-cording to the results of colour doppler ultrasound,in the treatment group the total effective rate was 83.3%, which was higher than that in the control group(66.7%) .Conclusion:Electroacupuncture combined with Chi-nese medicine has a more obvious effect on asymptomatic hepatolithiasis compared with the effect of Danshu soft capsules.

  16. Harm minimization among teenage drinkers

    DEFF Research Database (Denmark)

    Jørgensen, Morten Hulvej; Curtis, Tine; Christensen, Pia Haudrup

    2007-01-01

    AIM: To examine strategies of harm minimization employed by teenage drinkers. DESIGN, SETTING AND PARTICIPANTS: Two periods of ethnographic fieldwork were conducted in a rural Danish community of approximately 2000 inhabitants. The fieldwork included 50 days of participant observation among 13......-16-year-olds (n = 93) as well as 26 semistructured interviews with small self-selected friendship groups of 15-16-year-olds (n = 32). FINDINGS: The teenagers participating in the present study were more concerned about social than health risks. The informants monitored their own level of intoxication....... In regulating the social context of drinking they relied on their personal experiences more than on formalized knowledge about alcohol and harm, which they had learned from prevention campaigns and educational programmes. CONCLUSIONS: In this study we found that teenagers may help each other to minimize alcohol...

  17. On the Hopcroft's minimization algorithm

    CERN Document Server

    Paun, Andrei

    2007-01-01

    We show that the absolute worst case time complexity for Hopcroft's minimization algorithm applied to unary languages is reached only for de Bruijn words. A previous paper by Berstel and Carton gave the example of de Bruijn words as a language that requires O(n log n) steps by carefully choosing the splitting sets and processing these sets in a FIFO mode. We refine the previous result by showing that the Berstel/Carton example is actually the absolute worst case time complexity in the case of unary languages. We also show that a LIFO implementation will not achieve the same worst time complexity for the case of unary languages. Lastly, we show that the same result is valid also for the cover automata and a modification of the Hopcroft's algorithm, modification used in minimization of cover automata.

  18. A Minimally Symmetric Higgs Boson

    CERN Document Server

    Low, Ian

    2014-01-01

    Models addressing the naturalness of a light Higgs boson typically employ symmetries, either bosonic or fermionic, to stabilize the Higgs mass. We consider a setup with the minimal amount of symmetries: four shift symmetries acting on the four components of the Higgs doublet, subject to the constraints of linearly realized SU(2)xU(1) electroweak symmetry. Up to terms that explicitly violate the shift symmetries, the effective lagrangian can be derived, irrespective of the spontaneously broken group G in the ultraviolet, and is universal in all models where the Higgs arises as a pseudo-Nambu-Goldstone boson (PNGB). Very high energy scatterings of vector bosons could provide smoking gun signals of a minimally symmetric Higgs boson.

  19. Consistency of trace norm minimization

    CERN Document Server

    Bach, Francis

    2007-01-01

    Regularization by the sum of singular values, also referred to as the trace norm, is a popular technique for estimating low rank rectangular matrices. In this paper, we extend some of the consistency results of the Lasso to provide necessary and sufficient conditions for rank consistency of trace norm minimization with the square loss. We also provide an adaptive version that is rank consistent even when the necessary condition for the non adaptive version is not fulfilled.

  20. Principle of minimal work fluctuations.

    Science.gov (United States)

    Xiao, Gaoyang; Gong, Jiangbin

    2015-08-01

    Understanding and manipulating work fluctuations in microscale and nanoscale systems are of both fundamental and practical interest. For example, in considering the Jarzynski equality 〈e-βW〉=e-βΔF, a change in the fluctuations of e-βW may impact how rapidly the statistical average of e-βW converges towards the theoretical value e-βΔF, where W is the work, β is the inverse temperature, and ΔF is the free energy difference between two equilibrium states. Motivated by our previous study aiming at the suppression of work fluctuations, here we obtain a principle of minimal work fluctuations. In brief, adiabatic processes as treated in quantum and classical adiabatic theorems yield the minimal fluctuations in e-βW. In the quantum domain, if a system initially prepared at thermal equilibrium is subjected to a work protocol but isolated from a bath during the time evolution, then a quantum adiabatic process without energy level crossing (or an assisted adiabatic process reaching the same final states as in a conventional adiabatic process) yields the minimal fluctuations in e-βW, where W is the quantum work defined by two energy measurements at the beginning and at the end of the process. In the classical domain where the classical work protocol is realizable by an adiabatic process, then the classical adiabatic process also yields the minimal fluctuations in e-βW. Numerical experiments based on a Landau-Zener process confirm our theory in the quantum domain, and our theory in the classical domain explains our previous numerical findings regarding the suppression of classical work fluctuations [G. Y. Xiao and J. B. Gong, Phys. Rev. E 90, 052132 (2014)].

  1. Risk minimization and portfolio diversification

    OpenAIRE

    Farzad Pourbabaee; Minsuk Kwak; Traian A. Pirvu

    2014-01-01

    We consider the problem of minimizing capital at risk in the Black-Scholes setting. The portfolio problem is studied given the possibility that a correlation constraint between the portfolio and a financial index is imposed. The optimal portfolio is obtained in closed form. The effects of the correlation constraint are explored; it turns out that this portfolio constraint leads to a more diversified portfolio.

  2. Outcomes After Minimally Invasive Esophagectomy

    Science.gov (United States)

    Luketich, James D.; Pennathur, Arjun; Awais, Omar; Levy, Ryan M.; Keeley, Samuel; Shende, Manisha; Christie, Neil A.; Weksler, Benny; Landreneau, Rodney J.; Abbas, Ghulam; Schuchert, Matthew J.; Nason, Katie S.

    2014-01-01

    Background Esophagectomy is a complex operation and is associated with significant morbidity and mortality. In an attempt to lower morbidity, we have adopted a minimally invasive approach to esophagectomy. Objectives Our primary objective was to evaluate the outcomes of minimally invasive esophagectomy (MIE) in a large group of patients. Our secondary objective was to compare the modified McKeown minimally invasive approach (videothoracoscopic surgery, laparoscopy, neck anastomosis [MIE-neck]) with our current approach, a modified Ivor Lewis approach (laparoscopy, videothoracoscopic surgery, chest anastomosis [MIE-chest]). Methods We reviewed 1033 consecutive patients undergoing MIE. Elective operation was performed on 1011 patients; 22 patients with nonelective operations were excluded. Patients were stratified by surgical approach and perioperative outcomes analyzed. The primary endpoint studied was 30-day mortality. Results The MIE-neck was performed in 481 (48%) and MIE-Ivor Lewis in 530 (52%). Patients undergoing MIE-Ivor Lewis were operated in the current era. The median number of lymph nodes resected was 21. The operative mortality was 1.68%. Median length of stay (8 days) and ICU stay (2 days) were similar between the 2 approaches. Mortality rate was 0.9%, and recurrent nerve injury was less frequent in the Ivor Lewis MIE group (P < 0.001). Conclusions MIE in our center resulted in acceptable lymph node resection, postoperative outcomes, and low mortality using either an MIE-neck or an MIE-chest approach. The MIE Ivor Lewis approach was associated with reduced recurrent laryngeal nerve injury and mortality of 0.9% and is now our preferred approach. Minimally invasive esophagectomy can be performed safely, with good results in an experienced center. PMID:22668811

  3. Minimal Length, Measurability and Gravity

    Directory of Open Access Journals (Sweden)

    Alexander Shalyt-Margolin

    2016-03-01

    Full Text Available The present work is a continuation of the previous papers written by the author on the subject. In terms of the measurability (or measurable quantities notion introduced in a minimal length theory, first the consideration is given to a quantum theory in the momentum representation. The same terms are used to consider the Markov gravity model that here illustrates the general approach to studies of gravity in terms of measurable quantities.

  4. Optimizing Processes to Minimize Risk

    Science.gov (United States)

    Loyd, David

    2017-01-01

    NASA, like the other hazardous industries, has suffered very catastrophic losses. Human error will likely never be completely eliminated as a factor in our failures. When you can't eliminate risk, focus on mitigating the worst consequences and recovering operations. Bolstering processes to emphasize the role of integration and problem solving is key to success. Building an effective Safety Culture bolsters skill-based performance that minimizes risk and encourages successful engagement.

  5. BDD Minimization for Approximate Computing

    OpenAIRE

    Soeken, Mathias; Grosse, Daniel; Chandrasekharan, Arun; Drechsler, Rolf

    2016-01-01

    We present Approximate BDD Minimization (ABM) as a problem that has application in approximate computing. Given a BDD representation of a multi-output Boolean function, ABM asks whether there exists another function that has a smaller BDD representation but meets a threshold w.r.t. an error metric. We present operators to derive approximated functions and present algorithms to exactly compute the error metrics directly on the BDD representation. An experimental evaluation demonstrates the app...

  6. Torsional Rigidity of Minimal Submanifolds

    DEFF Research Database (Denmark)

    Markvorsen, Steen; Palmer, Vicente

    2006-01-01

    We prove explicit upper bounds for the torsional rigidity of extrinsic domains of minimal submanifolds $P^m$ in ambient Riemannian manifolds $N^n$ with a pole $p$. The upper bounds are given in terms of the torsional rigidities of corresponding Schwarz symmetrizations of the domains in warped...... for the torsional rigidity are actually attained and give conditions under which the geometric average of the stochastic mean exit time for Brownian motion at infinity is finite....

  7. Reservoir Operation to Minimize Sedimentation

    Directory of Open Access Journals (Sweden)

    Dyah Ari Wulandari

    2013-10-01

    Full Text Available The Wonogiri Reservoir capacity decreases rapidly, caused by serious sedimentation problems. In 2007, JICA was proposed a sediment storage reservoir with a new spillway for the purpose of sediment flushing / sluicing from The Keduang River. Due to the change of reservoir storage and change of reservoir system, it requires a sustainable reservoir operation technique. This technique is aimed to minimize the deviation between the input and output of sediments. The main objective of this study is to explore the optimal Wonogiri reservoir operation by minimizing the sediment trap. The CSUDP incremental dynamic programming procedure is used for the model optimization.  This new operating rules will also simulate a five years operation period, to show the effect of the implemented techniques. The result of the study are the newly developed reservoir operation system has many advantages when compared to the actual operation system and the disadvantage of this developed system is that the use is mainly designed for a wet hydrologic year, since its performance for the water supply is lower than the actual reservoir operations.Doi: 10.12777/ijse.6.1.16-23 [How to cite this article:  Wulandari, D.A., Legono, D., and Darsono, S., 2014. Reservoir Operation to Minimize Sedimentation. International Journal of Science and Engineering, 5(2,61-65. Doi: 10.12777/ijse.6.1.16-23] Normal 0 false false false EN-US X-NONE X-NONE

  8. Minimally invasive paediatric cardiac surgery.

    Science.gov (United States)

    Bacha, Emile; Kalfa, David

    2014-01-01

    The concept of minimally invasive surgery for congenital heart disease in paediatric patients is broad, and has the aim of reducing the trauma of the operation at each stage of management. Firstly, in the operating room using minimally invasive incisions, video-assisted thoracoscopic and robotically assisted surgery, hybrid procedures, image-guided intracardiac surgery, and minimally invasive cardiopulmonary bypass strategies. Secondly, in the intensive-care unit with neuroprotection and 'fast-tracking' strategies that involve early extubation, early hospital discharge, and less exposure to transfused blood products. Thirdly, during postoperative mid-term and long-term follow-up by providing the children and their families with adequate support after hospital discharge. Improvement of these strategies relies on the development of new devices, real-time multimodality imaging, aids to instrument navigation, miniaturized and specialized instrumentation, robotic technology, and computer-assisted modelling of flow dynamics and tissue mechanics. In addition, dedicated multidisciplinary co-ordinated teams involving congenital cardiac surgeons, perfusionists, intensivists, anaesthesiologists, cardiologists, nurses, psychologists, and counsellors are needed before, during, and after surgery to go beyond apparent technological and medical limitations with the goal to 'treat more while hurting less'.

  9. Radiative accidental matter

    CERN Document Server

    Sierra, D Aristizabal; Wegman, D

    2016-01-01

    Accidental matter models are scenarios where the beyond-the-standard model physics preserves all the standard model accidental and approximate symmetries up to a cutoff scale related with lepton number violation. We study such scenarios assuming that the new physics plays an active role in neutrino mass generation, and show that this unavoidably leads to radiatively induced neutrino masses. We systematically classify all possible models and determine their viability by studying electroweak precision data, big bang nucleosynthesis and electroweak perturbativity, finding that the latter places the most stringent constraints on the mass spectra. These results allow the identification of minimal radiative accidental matter models for which perturbativity is lost at high scales. We calculate radiative charged-lepton flavor violating processes in these setups, and show that $\\mu\\to e \\gamma$ has a rate well within MEG sensitivity provided the lepton-number violating scale is at or below $10^6\\,$ GeV, a value (natur...

  10. Radiation Therapy: Professions in Radiation Therapy

    Science.gov (United States)

    ... Resources Professions Site Index A-Z Professions in Radiation Therapy Radiation Oncologist Therapeutic Medical Physicist Radiation Therapist Dosimetrist Radiation Oncology Nurse Social Worker Dietitian Radiation Oncologist Radiation oncologists are physicians who oversee the ...

  11. Minimal lepton flavor violating realizations of minimal seesaw models

    CERN Document Server

    Sierra, Diego Aristizabal; Kamenik, Jernej F

    2012-01-01

    We study the implications of the global U(1)R symmetry present in minimal lepton flavor violating implementations of the seesaw mechanism for neutrino masses. In the context of minimal type I seesaw scenarios with a slightly broken U(1)R, we show that, depending on the R-charge assignments, two classes of generic models can be identified. Models where the right-handed neutrino masses and the lepton number breaking scale are decoupled, and models where the parameters that slightly break the U(1)R induce a suppression in the light neutrino mass matrix. We show that within the first class of models, contributions of right-handed neutrinos to charged lepton flavor violating processes are severely suppressed. Within the second class of models we study the charged lepton flavor violating phenomenology in detail, focusing on mu to e gamma, mu to 3e and mu to e conversion in nuclei. We show that sizable contributions to these processes are naturally obtained for right-handed neutrino masses at the TeV scale. We then ...

  12. Minimal families of curves on surfaces

    KAUST Repository

    Lubbes, Niels

    2014-11-01

    A minimal family of curves on an embedded surface is defined as a 1-dimensional family of rational curves of minimal degree, which cover the surface. We classify such minimal families using constructive methods. This allows us to compute the minimal families of a given surface.The classification of minimal families of curves can be reduced to the classification of minimal families which cover weak Del Pezzo surfaces. We classify the minimal families of weak Del Pezzo surfaces and present a table with the number of minimal families of each weak Del Pezzo surface up to Weyl equivalence.As an application of this classification we generalize some results of Schicho. We classify algebraic surfaces that carry a family of conics. We determine the minimal lexicographic degree for the parametrization of a surface that carries at least 2 minimal families. © 2014 Elsevier B.V.

  13. Minimally invasive PCNL-MIP.

    Science.gov (United States)

    Zanetti, Stefano Paolo; Boeri, Luca; Gallioli, Andrea; Talso, Michele; Montanari, Emanuele

    2017-01-01

    Miniaturized percutaneous nephrolithotomy (mini-PCNL) has increased in popularity in recent years and is now widely used to overcome the therapeutic gap between conventional PCNL and less-invasive procedures such as shock wave lithotripsy (SWL) or flexible ureterorenoscopy (URS) for the treatment of renal stones. However, despite its minimally invasive nature, the superiority in terms of safety, as well as the similar efficacy of mini-PCNL compared to conventional procedures, is still under debate. The aim of this chapter is to present one of the most recent advancements in terms of mini-PCNL: the Karl Storz "minimally invasive PCNL" (MIP). A literature search for original and review articles either published or e-published up to December 2016 was performed using Google and the PubMed database. Keywords included: minimally invasive PCNL; MIP. The retrieved articles were gathered and examined. The complete MIP set is composed of different sized rigid metallic fiber-optic nephroscopes and different sized metallic operating sheaths, according to which the MIP is categorized into extra-small (XS), small (S), medium (M) and large (L). Dilation can be performed either in one-step or with a progressive technique, as needed. The reusable devices of the MIP and vacuum cleaner efect make PCNL with this set a cheap procedure. The possibility to shift from a small to a larger instrument within the same set (Matrioska technique) makes MIP a very versatile technique suitable for the treatment of almost any stone. Studies in the literature have shown that MIP is equally effective, with comparable rates of post-operative complications, as conventional PCNL, independently from stone size. MIP does not represent a new technique, but rather a combination of the last ten years of PCNL improvements in a single system that can transversally cover all available techniques in the panorama of percutaneous stone treatment.

  14. Minimal dispersion refractive index profiles.

    Science.gov (United States)

    Feit, M D

    1979-09-01

    The analogy between optics and quantum mechanics is exploited by considering a 2-D quantum system whose Schroedinger equation is closely related to the wave equation for light propagation in an optical fiber. From this viewpoint, Marcatili's condition for minimal-dispersion-refractive-index profiles, and the Olshansky- Keck formula for rms pulse spreading in an alpha-profile fiber may be derived without recourse to the WKB approximation. Besides affording physical insight into these results, the present approach points out a possible limitation in their application to real fibers.

  15. Minimal sets of Reidemeister moves

    CERN Document Server

    Polyak, Michael

    2009-01-01

    It is well known that any two diagrams representing the same oriented link are related by a finite sequence of Reidemeister moves O1, O2 and O3. Depending on orientations of fragments involved in the moves, one may distinguish 4 different versions of each of the O1 and O2 moves, and 8 versions of the O3 move. We introduce a minimal generating set of oriented Reidemeister moves, which includes two moves of types O1 and O2, and only one move of type O3. We then consider other sets of moves and show that only few of them generate all Reidemeister moves.

  16. About the ZOOM minimization package

    Energy Technology Data Exchange (ETDEWEB)

    Fischler, M.; Sachs, D.; /Fermilab

    2004-11-01

    A new object-oriented Minimization package is available for distribution in the same manner as CLHEP. This package, designed for use in HEP applications, has all the capabilities of Minuit, but is a re-write from scratch, adhering to modern C++ design principles. A primary goal of this package is extensibility in several directions, so that its capabilities can be kept fresh with as little maintenance effort as possible. This package is distinguished by the priority that was assigned to C++ design issues, and the focus on producing an extensible system that will resist becoming obsolete.

  17. Prepulse minimization in KALI-5000

    Science.gov (United States)

    Kumar, D. Durga Praveen; Mitra, S.; Senthil, K.; Sharma, Vishnu K.; Singh, S. K.; Roy, A.; Sharma, Archana; Nagesh, K. V.; Chakravarthy, D. P.

    2009-07-01

    A pulse power system (1 MV, 50 kA, and 100 ns) based on Marx generator and Blumlein pulse forming line has been built for generating high power microwaves. The Blumlein configuration poses a prepulse problem and hence the diode gap had to be increased to match the diode impedance to the Blumlein impedance during the main pulse. A simple method to eliminate prepulse voltage using a vacuum sparkgap and a resistor is given. Another fundamental approach of increasing the inductance of Marx generator to minimize the prepulse voltage is also presented. Experimental results for both of these configurations are given.

  18. Risk minimization through portfolio replication

    Science.gov (United States)

    Ciliberti, S.; Mã©Zard, M.

    2007-05-01

    We use a replica approach to deal with portfolio optimization problems. A given risk measure is minimized using empirical estimates of asset values correlations. We study the phase transition which happens when the time series is too short with respect to the size of the portfolio. We also study the noise sensitivity of portfolio allocation when this transition is approached. We consider explicitely the cases where the absolute deviation and the conditional value-at-risk are chosen as a risk measure. We show how the replica method can study a wide range of risk measures, and deal with various types of time series correlations, including realistic ones with volatility clustering.

  19. 331 Models and Grand Unification: From Minimal SU(5) to Minimal SU(6)

    CERN Document Server

    Deppisch, Frank F; Patra, Sudhanwa; Sarkar, Utpal; Valle, Josè W F

    2016-01-01

    We consider the possibility of grand unification of the $\\mathrm{ SU(3)_c \\otimes SU(3)_L \\otimes U(1)_X}$ model in an SU(6) gauge unification group. Two possibilities arise. Unlike other conventional grand unified theories, in SU(6) one can embed the $\\mathrm{ SU(3)_c \\otimes SU(3)_L \\otimes U(1)_X}$ model as a subgroup such that different multiplets appear with different multiplicities. Such a scenario may emerge from the flux breaking of the unified group in an E(6) F-theory GUT. This provides new ways of achieving gauge coupling unification in $\\mathrm{ SU(3)_c \\otimes SU(3)_L \\otimes U(1)_X}$ models while providing the radiative origin of neutrino masses. Alternatively, a sequential variant of the $\\mathrm{ SU(3)_c \\otimes SU(3)_L \\otimes U(1)_X}$ model can fit within a minimal SU(6) grand unification, which in turn can be a natural E(6) subgroup. This minimal SU(6) embedding does not require any bulk exotics to account for the chiral families while allowing for a TeV scale $\\mathrm{ SU(3)_c \\otimes SU(3...

  20. A minimal four-family supergravity model

    CERN Document Server

    Gunion, J F; Pois, H; McKay, Douglas W

    1996-01-01

    We investigate the phenomenology of minimal four-family MSSM supergravity theories containing an additional generation of heavy fermions along with their superpartners. We demand: gauge coupling constant unification at high energy scales; perturbative values for all Yukawa couplings for energy scales \\leq \\mgut; radiative electroweak symmetry breaking via renormalization group evolution; and a neutral LSP. The perturbative constraints imply a light fourth-family quark and lepton spectrum, and \\tanb\\lsim 3. The lightest CP-even Higgs mass is increased. Fourth-family Yukawa coupling contributions to the evolution of scalar masses lead to unexpected mass hierarchies; \\eg\\ the \\staupone is generally the lightest slepton and the lightest squark is the \\wt\\bpr_1. A significant lower bound is placed on the gluino mass by the requirement that the \\staupone not be the LSP. Sleptons of the first two families are much more massive compared to the LSP and other neutralinos and charginos than in the three-family models, a...

  1. QCD Radiation off Heavy Particles

    CERN Document Server

    Sjöstrand, Torbjörn

    2000-01-01

    An algorithm for an improved description of final-state QCD radiation is introduced. It is matched to the first-order matrix elements for gluon emission in a host of decays, for processes within the Standard Model and the Minimal Supersymmetric extension thereof.

  2. Risk minimization by experimental mechanics

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    Experimental mechanics has to undertake new functions to confirm theoretical perceptions and to check results of numerical analysis, because such results are dependent on the validity of assumptions and suppositions which generally are necessary to enable mathematical analysis of complex problems. Methods of experimental mechanics have become essential to design structures and products of a large variety to save raw materials and energy, to improve safety against failure and reliability of products, structures and even complex technical systems. Experimental methods are applied in system identification of complex structures. They are developed also as tools for supervising operating systems, machinery and installations as well as engineering structures, in order to get reliable informations on the life-time, to guarantee a higher degree of safety and to minimize risks. Therefore, methods of experimental mechanics are quite essential in developing strategies of riskmanagement. The contributions to this report are dealing with new theoretical perceptions, practical applications and experiences according to the objectives of the international symposium on 'Risk Minimization by Experimental Mechanics'. (orig.).

  3. Noise Tolerance under Risk Minimization

    CERN Document Server

    Manwani, Naresh

    2011-01-01

    In this paper we explore the problem of noise tolerant learning of classifiers. We formulate the problem as follows. We assume that there is an ${\\bf unobservable}$ training set which is noise-free. The actual training set given to the learning algorithm is obtained from this ideal data set by corrupting the class label of each example where the probability that the class label on an example is corrupted is a function of the feature vector of the example. This would account for almost all kinds of noisy data one may encounter in practice. We say that a learning method is noise tolerant if the classifiers learnt with the ideal noise-free data and with noisy data have the same classification accuracy on the noise-free data. In this paper we analyze the noise tolerant properties of risk minimization, which is a generic method for learning classifiers. We consider different loss functions such as 0-1 loss, hinge loss, exponential loss, squared error loss etc. We show that the risk minimization under 0-1 loss func...

  4. Concentrator design to minimize LCOE

    Science.gov (United States)

    McDonald, Mark; Horne, Steve; Conley, Gary

    2007-09-01

    The Levelized Cost of Energy (LCOE) takes into account more than just the cost of power output. It encompasses product longevity, performance degradation and the costs associated with delivering energy to the grid tie point. Concentrator optical design is one of the key components to minimizing the LCOE, by affecting conversion efficiency, acceptance angle and the amount of energy concentrated on the receiver. Optical systems for concentrators, even those at high concentrations ( >350X) can be designed by straightforward techniques, and will operate under most circumstances. Adding requirements for generous acceptance angles, non-destructive off-axis operation, safety and high efficiency however, complicate the design. Furthermore, the demands of high volume manufacturing, efficient logistics, minimal field commissioning time and low cost lead to quite complicated, system level design trade-offs. The technology which we will discuss features an array of reflective optics, scaled to be fabricated by techniques used in the automotive industry. The design couples a two-element imaging system to a non-imaging total internal reflection tertiary in a very compact design, with generous tolerance margins. Several optical units are mounted in a housing, which protects the optics and assists with dissipating waste heat. This paper outlines the key elements in the design of SolFocus concentrator optics, and discusses tradeoffs and experience with various design approaches.

  5. Laparoscopic colonic resection in inflammatory bowel disease: minimal surgery, minimal access and minimal hospital stay.

    LENUS (Irish Health Repository)

    Boyle, E

    2008-11-01

    Laparoscopic surgery for inflammatory bowel disease (IBD) is technically demanding but can offer improved short-term outcomes. The introduction of minimally invasive surgery (MIS) as the default operative approach for IBD, however, may have inherent learning curve-associated disadvantages. We hypothesise that the establishment of MIS as the standard operative approach does not increase patient morbidity as assessed in the initial period of its introduction into a specialised unit, and that it confers earlier postoperative gastrointestinal recovery and reduced hospitalisation compared with conventional open resection.

  6. Pelvic radiation - discharge

    Science.gov (United States)

    Radiation of the pelvis - discharge; Cancer treatment - pelvic radiation; Prostate cancer - pelvic radiation; Ovarian cancer - pelvic radiation; Cervical cancer - pelvic radiation; Uterine cancer - pelvic radiation; Rectal cancer - pelvic radiation

  7. Absorber for terahertz radiation management

    Science.gov (United States)

    Biallas, George Herman; Apeldoorn, Cornelis; Williams, Gwyn P.; Benson, Stephen V.; Shinn, Michelle D.; Heckman, John D.

    2015-12-08

    A method and apparatus for minimizing the degradation of power in a free electron laser (FEL) generating terahertz (THz) radiation. The method includes inserting an absorber ring in the FEL beam path for absorbing any irregular THz radiation and thus minimizes the degradation of downstream optics and the resulting degradation of the FEL output power. The absorber ring includes an upstream side, a downstream side, and a plurality of wedges spaced radially around the absorber ring. The wedges form a scallop-like feature on the innermost edges of the absorber ring that acts as an apodizer, stopping diffractive focusing of the THz radiation that is not intercepted by the absorber. Spacing between the scallop-like features and the shape of the features approximates the Bartlett apodization function. The absorber ring provides a smooth intensity distribution, rather than one that is peaked on-center, thereby eliminating minor distortion downstream of the absorber.

  8. Rituximab in Minimal Change Disease

    Directory of Open Access Journals (Sweden)

    Nima Madanchi

    2017-03-01

    Full Text Available Treatment with rituximab, a monoclonal antibody against the B-lymphocyte surface protein CD20, leads to the depletion of B cells. Recently, rituximab was reported to effectively prevent relapses of glucocorticoid-dependent or frequently relapsing minimal change disease (MCD. MCD is thought to be T-cell mediated; how rituximab controls MCD is not understood. In this review, we summarize key clinical studies demonstrating the efficacy of rituximab in idiopathic nephrotic syndrome, mainly MCD. We then discuss immunological features of this disease and potential mechanisms of action of rituximab in its treatment based on what is known about the therapeutic action of rituximab in other immune-mediated disorders. We believe that studies aimed at understanding the mechanisms of action of rituximab in MCD will provide a novel approach to resolve the elusive immune pathophysiology of MCD.

  9. Minimally packed phases in holography

    CERN Document Server

    Donos, Aristomenis

    2015-01-01

    We numerically construct asymptotically AdS black brane solutions of $D=4$ Einstein-Maxwell theory coupled to a pseudoscalar. The solutions are holographically dual to $d=3$ CFTs held at constant chemical potential and magnetic field that spontaneously break translation invariance leading to the spontaneous formation of abelian and momentum magnetisation currents flowing around the plaquettes of a periodic Bravais lattice. We analyse the three-dimensional moduli space of lattice solutions, which are generically oblique, and show that the free energy is minimised by the triangular lattice, associated with minimal packing of circles in the plane. The triangular structure persists at low temperatures indicating the existence of novel crystalline ground states.

  10. A minimally invasive smile enhancement.

    Science.gov (United States)

    Peck, Fred H

    2014-01-01

    Minimally invasive dentistry refers to a wide variety of dental treatments. On the restorative aspect of dental procedures, direct resin bonding can be a very conservative treatment option for the patient. When tooth structure does not need to be removed, the patient benefits. Proper treatment planning is essential to determine how conservative the restorative treatment will be. This article describes the diagnosis, treatment options, and procedural techniques in the restoration of 4 maxillary anterior teeth with direct composite resin. The procedural steps are reviewed with regard to placing the composite and the variety of colors needed to ensure a natural result. Finishing and polishing of the composite are critical to ending with a natural looking dentition that the patient will be pleased with for many years.

  11. Determining Knots by Minimizing Energy

    Institute of Scientific and Technical Information of China (English)

    Cai-Ming Zhang; Hui-Jian Han; Fuhua Frank Cheng

    2006-01-01

    A new method for determining knots to construct polynomial curves is presented. At each data point, a quadric curve which passes three consecutive points is constructed. The knots for constructing the quadric curve are determined by minimizing the internal strain energy, which can be regarded as a function of the angle. The function of the angle is expanded as a Taylor series with two terms, then the two knot intervals between the three consecutive points are defined by linear expression. Between the two consecutive points, there are two knot intervals, and the combination of the two knot intervals is used to define the final knot interval. A comparison of the new method with several existing methods is included.

  12. [MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT].

    Science.gov (United States)

    Tabata, Minoru

    2016-03-01

    Minimally invasive aortic valve replacement (MIAVR) is defined as aortic valve replacement avoiding full sternotomy. Common approaches include a partial sternotomy right thoracotomy, and a parasternal approach. MIAVR has been shown to have advantages over conventional AVR such as shorter length of stay and smaller amount of blood transfusion and better cosmesis. However, it is also known to have disadvantages such as longer cardiopulmonary bypass and aortic cross-clamp times and potential complications related to peripheral cannulation. Appropriate patient selection is very important. Since the procedure is more complex than conventional AVR, more intensive teamwork in the operating room is essential. Additionally, a team approach during postoperative management is critical to maximize the benefits of MIAVR.

  13. Minimization over randomly selected lines

    Directory of Open Access Journals (Sweden)

    Ismet Sahin

    2013-07-01

    Full Text Available This paper presents a population-based evolutionary optimization method for minimizing a given cost function. The mutation operator of this method selects randomly oriented lines in the cost function domain, constructs quadratic functions interpolating the cost function at three different points over each line, and uses extrema of the quadratics as mutated points. The crossover operator modifies each mutated point based on components of two points in population, instead of one point as is usually performed in other evolutionary algorithms. The stopping criterion of this method depends on the number of almost degenerate quadratics. We demonstrate that the proposed method with these mutation and crossover operations achieves faster and more robust convergence than the well-known Differential Evolution and Particle Swarm algorithms.

  14. Minimally invasive aortic valve replacement

    DEFF Research Database (Denmark)

    Foghsgaard, Signe; Schmidt, Thomas Andersen; Kjaergard, Henrik K

    2009-01-01

    In this descriptive prospective study, we evaluate the outcomes of surgery in 98 patients who were scheduled to undergo minimally invasive aortic valve replacement. These patients were compared with a group of 50 patients who underwent scheduled aortic valve replacement through a full sternotomy....... The 30-day mortality rate for the 98 patients was zero, although 14 of the 98 mini-sternotomies had to be converted to complete sternotomies intraoperatively due to technical problems. Such conversion doubled the operative time over that of the planned full sternotomies. In the group of patients whose...... is an excellent operation in selected patients, but its true advantages over conventional aortic valve replacement (other than a smaller scar) await evaluation by means of randomized clinical trial. The "extended mini-aortic valve replacement" operation, on the other hand, is a risky procedure that should...

  15. Normal tissue toxicity after small field hypofractionated stereotactic body radiation

    OpenAIRE

    Constine Louis S; Milano Michael T; Okunieff Paul

    2008-01-01

    Abstract Stereotactic body radiation (SBRT) is an emerging tool in radiation oncology in which the targeting accuracy is improved via the detection and processing of a three-dimensional coordinate system that is aligned to the target. With improved targeting accuracy, SBRT allows for the minimization of normal tissue volume exposed to high radiation dose as well as the escalation of fractional dose delivery. The goal of SBRT is to minimize toxicity while maximizing tumor control. This review ...

  16. Overview of the Martian radiation environment experiment

    Energy Technology Data Exchange (ETDEWEB)

    Zeitlin, C.; Cleghorn, T.F.; Cucinotta, F.A.; Saganti, P.; Andersen, V.; Lee, K.T.; Pinsky, L.S.; Atwell, W.; Turner, R.; Badhwar, G.

    2004-12-01

    Space radiation presents a hazard to astronauts, particularly those journeying outside the protective influence of the geomagnetosphere. Crews on future missions to Mars will be exposed to the harsh radiation environment of deep space during the transit between Earth and Mars. Once on Mars, they will encounter radiation that is only slightly reduced, compared to free space, by the thin Martian atmosphere. NASA is obliged to minimize, where possible, the radiation exposures received by astronauts. Thus, as a precursor to eventual human exploration, it is necessary to measure the Martian radiation environment in detail. The MARIE experiment, aboard the 2001 Mars Odyssey spacecraft, is returning the first data that bear directly on this problem. Here we provide an overview of the experiment, including introductory material on space radiation and radiation dosimetry, a description of the detector, model predictions of the radiation environment at Mars, and preliminary dose-rate data obtained at Mars.

  17. High and low frequency probe combined using for diagnosed infant urinary Lithiasis by ultrasound%高、低频超声探头联合应用在婴幼儿泌尿系结石诊断的价值

    Institute of Scientific and Technical Information of China (English)

    解婷; 李红; 高传江; 白洁茹; 王玉玲; 赵冬平

    2009-01-01

    目的 探讨高、低频探头联合应用在婴幼儿(0~3岁)泌尿系结石超声检查中的价值.方法 分别应用高、低频探头对1800例婴幼儿进行常规肾脏超声检查,并对检出阳性率患者予以分类、追踪,对高、低频探头检查的不同声像进行总结分析,对比研究.结果 A方法 诊断泌尿系结石的敏感性为55.3%,B方法 为94.7%.结论高、低频探头的联合应用较单纯应用普通低频探头检查更有助于诊断婴幼儿泌尿系结石.%Objective To discuss the value of combined using high and low frequency probe in chec-king the infant renal diseases. Methods Using high and low frequency probe check 1800 cases in infant renal respectively, And to classify and trace the positive rate patients. To summarize the different imageing on using high and low frequency probe,contrast the results and study them. Results Susceptibility of pulsed A mode was 55.3 % for diagnosis of urinary Lithiasis, B mode is 94.7%. Conclusion Combined using high and low frequen-cy probe is much more help to diagnose in checking the infant urinary Lithiasis.

  18. Atoms, Radiation, and Radiation Protection

    CERN Document Server

    Turner, James E

    2007-01-01

    Atoms, Radiation, and Radiation Protection offers professionals and advanced students a comprehensive coverage of the major concepts that underlie the origins and transport of ionizing radiation in matter. Understanding atomic structure and the physical mechanisms of radiation interactions is the foundation on which much of the current practice of radiological health protection is based. The work covers the detection and measurement of radiation and the statistical interpretation of the data. The procedures that are used to protect man and the environment from the potential harmful effects of

  19. Radiation Chemistry

    Science.gov (United States)

    Wojnárovits, L.

    Ionizing radiation causes chemical changes in the molecules of the interacting medium. The initial molecules change to new molecules, resulting in changes of the physical, chemical, and eventually biological properties of the material. For instance, water decomposes to its elements H2 and O2. In polymers, degradation and crosslinking take place. In biopolymers, e.g., DNS strand breaks and other alterations occur. Such changes are to be avoided in some cases (radiation protection), however, in other cases they are used for technological purposes (radiation processing). This chapter introduces radiation chemistry by discussing the sources of ionizing radiation (radionuclide sources, machine sources), absorption of radiation energy, techniques used in radiation chemistry research, and methods of absorbed energy (absorbed dose) measurements. Radiation chemistry of different classes of inorganic (water and aqueous solutions, inorganic solids, ionic liquids (ILs)) and organic substances (hydrocarbons, halogenated compounds, polymers, and biomolecules) is discussed in concise form together with theoretical and experimental backgrounds. An essential part of the chapter is the introduction of radiation processing technologies in the fields of polymer chemistry, food processing, and sterilization. The application of radiation chemistry to nuclear technology and to protection of environment (flue gas treatment, wastewater treatment) is also discussed.

  20. 中西医综合治疗肾结石120例临床观察%Clinical Observation on Renal Lithiasis with Therapy of Integrated Chinese and Western medicine treatment, A Report of 120Cases

    Institute of Scientific and Technical Information of China (English)

    李红霞; 马金荣; 裴国超; 潘红梅; 高萍

    2015-01-01

    目的:观察中西医综合治疗肾结石的疗效。方法:将120例患者半随机分为治疗组40例,综合组40例,对照组40例。治疗组采用中西医结合疗法,综合组采用中西医综合治疗,对照组采用西医疗法。结果:对照组完全缓解8例,部分缓解17例,无效15例,总有效率62.5%;治疗组完全缓解20例,部分缓解15例,无效5例,总有效率达87.5%,综合组完全缓解26例,部分缓解11例,无效3例,总有效率达92.5%,三组总有效率相比,治疗组与对照组对比,均有统计学差异(P<0.01),两治疗组对比,有统计学差异(P<0.05)。结论:中西医综合治疗肾结石的疗效优于单纯西医疗法。%Objective: To investigate the curative effect of Integrated Chinese and Western medicine treatment on renal lithiasis. Method:120 cases were divided into treatment group, consolidated group and control group quasi-randomized. The treatment group included 40 cases, consolidated group included 40 cases and the control group included 40 cases. Combination of TCM with Western Medicine was given to the treatment group, Consolidated group with Integrated Chinese and Western medicine and Routine western medicine was given to the control group. Result: In the control group, 8 cases were cured, 17 cases were excellen, and 15 cases were ineffective. The total effective rate was 62.5%.In the treatment group, 20 cases were cured, 15 cases were excellen, and 5 cases were ineffective. The total effective rate was 87.5%. In the consolidated group, 26 cases were cured, 11 cases were excellen, and 3 cases were ineffective. The total effective rate was 92.5%. Three groups compared to the total efficiency of the treatment group and control group comparison, were statistically significant (P<0.01), comparing the two treatment groups, there are significant differences(P<0.05). Conclusions: The efficacy of TCM and Western medicine treatment of kidney stones

  1. Active control of radiated sound using nearfield pressure sensing

    Institute of Scientific and Technical Information of China (English)

    CHEN Ke'an; YIN Xuefei

    2004-01-01

    Based on nearfield sound pressure sensing to pick up error information, an approach for constructing active acoustic structure to effectively reduce radiated sound power at low frequency is proposed. The idea is that a nearfield pressure after active control is used as error signals and transformed into an objective function in adaptive active control process.Firstly sound power expression using near-field pressure radiated from a flexible structure is derived, and then three kind of nearfield pressure based active control strategies, I.e. Minimization of radiated sound power, minimization of sound power for dominant radiation modes and minimization of sound power for modified dominant radiation modes are respectively presented and applied to active control of radiated single and broadband noise. Finally computer simulations on sound power reduction under three strategies are conducted and it is shown that the proposed active control strategies are invalid and considerable reduction in radiated sound power can be achieved.

  2. The Minimal Cost of Life in Space

    Science.gov (United States)

    Drysdale, A.; Rutkze, C.; Albright, L.; Ladue, R.

    Life in space requires protection from the external environment, provision of a suitable internal environment, provision of consumables to maintain life, and removal of wastes. Protection from the external environment will mainly require shielding from radiation and meteoroids. Provision of a suitable environment inside the spacecraft will require provision of suitable air pressure and composition, temperature, and protection from environmental toxins (trace contaminants) and pathogenic micro-organisms. Gravity may be needed for longer missions to avoid excessive changes such as decalcification and muscle degeneration. Similarly, the volume required per crewmember will increase as the mission duration increases. Consumables required include oxygen, food, and water. Nitrogen might be required, depending on the total pressure and non-metabolic losses. We normally provide these consumables from the Earth, with a greater or lesser degree of regeneration. In principle, all consumables can be regenerated. Water and air are easiest to regenerate. At the present time, food can only be regenerated by using plants, and higher plants at that. Waste must be removed, including carbon dioxide and other metabolic waste as well as trash such as food packaging, filters, and expended spare parts. This can be done by dumping or regeneration. The minimal cost of life in space would be to use a synthesis process or system to regenerate all consumables from wastes. As the efficiency of the various processes rises, the minimal cost of life support will fall. However, real world regeneration requires significant equipment, power, and crew time. Make-up will be required for those items that cannot be economically regenerated. For very inefficient processes, it might be cheaper to ship all or part of the consumables. We are currently far down the development curve, and for short missions it is cheaper to ship consumables. For longer duration missions, greater closure is cost effective

  3. Predictors of radiation exposure to providers during percutaneous nephrolithotomy

    Directory of Open Access Journals (Sweden)

    David L Wenzler

    2017-01-01

    Conclusion: Increased stone burden, partial or staghorn calculi, surgery and fluoroscopy duration, and absence of preexisting access were associated with high provider radiation exposure. Radiation safety awareness is essential to minimize exposure and to protect the patient and all providers from potential radiation injury.

  4. Radiation carcinogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Fry, R.J.M.

    1976-01-01

    The risk of iatrogenic tumors with radiation therapy is so outweighed by the benefit of cure that estimates of risk have not been considered necessary. However, with the introduction of chemotherapy, combined therapy, and particle radiation therapy, the comparative risks should be examined. In the case of radiation, total dose, fractionation, dose rate, dose distribution, and radiation quality should be considered in the estimation of risk. The biological factors that must be considered include incidence of tumors, latent period, degree of malignancy, and multiplicity of tumors. The risk of radiation induction of tumors is influenced by the genotype, sex, and age of the patient, the tissues that will be exposed, and previous therapy. With chemotherapy the number of cells at risk is usually markedly higher than with radiation therapy. Clearly the problem of the estimation of comparative risks is complex. This paper presents the current views on the comparative risks and the importance of the various factors that influence the estimation of risk.

  5. Radiation acoustics

    CERN Document Server

    Lyamshev, Leonid M

    2004-01-01

    Radiation acoustics is a developing field lying at the intersection of acoustics, high-energy physics, nuclear physics, and condensed matter physics. Radiation Acoustics is among the first books to address this promising field of study, and the first to collect all of the most significant results achieved since research in this area began in earnest in the 1970s.The book begins by reviewing the data on elementary particles, absorption of penetrating radiation in a substance, and the mechanisms of acoustic radiation excitation. The next seven chapters present a theoretical treatment of thermoradiation sound generation in condensed media under the action of modulated penetrating radiation and radiation pulses. The author explores particular features of the acoustic fields of moving thermoradiation sound sources, sound excitation by single high-energy particles, and the efficiency and optimal conditions of thermoradiation sound generation. Experimental results follow the theoretical discussions, and these clearl...

  6. Mini-Med School Planning Guide

    Science.gov (United States)

    National Institutes of Health, Office of Science Education, 2008

    2008-01-01

    Mini-Med Schools are public education programs now offered by more than 70 medical schools, universities, research institutions, and hospitals across the nation. There are even Mini-Med Schools in Ireland, Malta, and Canada! The program is typically a lecture series that meets once a week and provides "mini-med students" information on some of the…

  7. Robotic-assisted minimally invasive liver resection

    Directory of Open Access Journals (Sweden)

    Yao-Ming Wu

    2014-04-01

    Conclusion: Robotic assistance increased the percentage of minimally invasive liver resections and the percentage of major minimally invasive liver resections with comparable perioperative results. Robotic-assisted minimally invasive liver resection is feasible, but its role needs more accumulated experience to clarify.

  8. Hawking radiation

    Science.gov (United States)

    Parentani, Renaud; Spindel, Philippe

    2011-12-01

    Hawking radiation is the thermal radiation predicted to be spontaneously emitted by black holes. It arises from the steady conversion of quantum vacuum fluctuations into pairs of particles, one of which escaping at infinity while the other is trapped inside the black hole horizon. It is named after the physicist Stephen Hawking who derived its existence in 1974. This radiation reduces the mass of black holes and is therefore also known as black hole evaporation.

  9. Urinary pH and renal lithiasis.

    Science.gov (United States)

    Grases, F; Costa-Bauzá, A; Gomila, I; Ramis, M; García-Raja, A; Prieto, R M

    2012-02-01

    Formation of calcium oxalate crystals, either as monohydrate or dihydrate, is apparently unrelated to urinary pH because the solubilities of these salts are practically unaltered at physiologic urinary pH values. However, a urinary pH 6.0 may induce uric acid or calcium phosphate crystals formation, respectively, which under appropriate conditions may induce the development of the calcium oxalate calculi. We assessed the relationship between the urinary pH and the formation of different types of calculi. A retrospective study in 1,478 patients was done. We determined the composition, macrostructure, and microstructure of the calculi and the urinary pH, 50.9% of calcium oxalate monohydrate unattached calculi were present in patients with urinary pH 6.0, respectively. Infectious calculi were found primarily in patients with urinary pH >6.0 (50.7%). Only calcium oxalate monohydrate papillary calculi were associated with urinary pH between 5.5 and 6.0 (43.1%). Urine of pH 6.0 has an increased capacity to develop calcium phosphate crystals, which can act as a heterogeneous nuclei of calcium oxalate crystals. Oxalate monohydrate papillary calculi were associated to pH between 5.5 and 6.0 because the injured papilla acts as a heterogeneous nucleant. Consequently, measurement of urinary pH may be used to evaluate the lithogen risk of given urine.

  10. [Bone involvement in idiopathic calcium lithiasis].

    Science.gov (United States)

    Ghazali, A; Bataille, P; Solal, M C; Marié, A; Brazier, M; Sebert, J L; Prin, L; Fournier, A

    1995-01-01

    Bone involvement in idiopathic calcium nephrolithiasis is characterized by the following abnormalities: a) the bone density is decreased, the severity of bone loss being dependent upon the existence of hypercalciuria and upon the pathophysiology of this latter: it is inconsistent in the absence of hypercalciuria or when hypercalciuria is of the absorptive type I or II, whereas it is almost constant in fasting hypercalciuria without secondary hyperparathyroidism and constant and severe in the rare true renal hypercalciuria. b) The bone histology (which has been evaluated only in idiopathic hypercalciuric patients) mainly shows a defect in bone formation at the exception of the rare renal hypercalciuria. Osteoclastic hyperresorption is only seen in this latter type of hypercalciuria whereas in the other types of hypercalciuria only an increase of the total or inactive resorption surface is observed. This phenomenon is possibly explained only by a delayed refilling of the resorption lacunae secondary to the decreased bone formation. The osteoid thickness is either normal or decreased despite decrease in mineralization apposition rate which seems therefore to be secondary to the decreased bone formation. c) Symptomatic bone disease in hypercalciuric stone formers is exceptional and always related to a severe long term calcium restriction. d) The biochemical markers of bone resorption tend to be increased in idiopathic hypercalciuria. Hydroxyprolinuria is more often elevated than pyridinolinuria. However pyridinolinuria is negatively correlated to bone density. The contrast between the increase of these bone resorption markers and the usual normality of plasma PTH and of the osteoclastic resorptive surfaces, suggest the role of meat induced acid load which may favor inactive resorption by dissolution of bone buffers. A disturbed profile synthesis of cytokines which induce differentiation and proliferation of the osteoclasts and which modulate the osteoblastic proliferation and function (IL-1, IL-6, TNF-alpha, GM-CSF...) may play a role in the bone loss of calcium stone formers but further studies are necessary to precise its transient or permanent involvement in their bone disease. e) The decrease of bone formation may be explained by the suppressed PTH secretion which may be explained by hypercalcitriolemia. This excess of calcitriol synthesis may be secondary either to monocyte increased synthesis of IL-1 which stimulates the renal 1 alpha-hydroxylase by the mean of an increased PGE2 synthesis or to the relative hypophosphatemia of the calcium stone formers comparatively to healthy controls. Hypercalcitriolemia may originate from the activated monocyte itself. The decrease in bone formation may also be secondary to the action of monokines on the osteoblast differentiation and/or function.

  11. Intestinal obstruction for biliary lithiasis: case report

    Directory of Open Access Journals (Sweden)

    Miguel Enrique Rodriguez Rodriguez

    2017-06-01

    Full Text Available The biliary ileum is an infrequent complication of cholelithiasis, that is manifested as an intestinal obstruction, is more prevalent in aged people. The clinical square of the biliary ileum is diffuse and the Triad of Rigler is observed in less than 30% of the patient one. The surgical treatment goes from enterotomía and litotricia to the colecistectomía with treatment of the water-pipe. The case of a female, 86-year-old patient is presented that after a week of symptoms and of medical treatment it was detected the presence of a mechanical intestinal obstruction for which the patient underwent emergency surgery. As the cause of occlusion it was found a thick gallstone in a jejunal loop.

  12. Medical waste: a minimal hazard.

    Science.gov (United States)

    Keene, J H

    1991-11-01

    Medical waste is a subset of municipal waste, and regulated medical waste comprises less than 1% of the total municipal waste volume in the United States. As part of the overall waste stream, medical waste does contribute in a relative way to the aesthetic damage of the environment. Likewise, some small portion of the total release of hazardous chemicals and radioactive materials is derived from medical wastes. These comments can be made about any generated waste, regulated or unregulated. Healthcare professionals, including infection control personnel, microbiologists, public health officials, and others, have unsuccessfully argued that there is no evidence that past methods of treatment and disposal of regulated medical waste constitute any public health hazard. Historically, discovery of environmental contamination by toxic chemical disposal has followed assurances that the material was being disposed of in a safe manner. Therefore, a cynical public and its elected officials have demanded proof that the treatment and disposal of medical waste (i.e., infectious waste) do not constitute a public health hazard. Existent studies on municipal waste provide that proof. In order to argue that the results of these municipal waste studies are demonstrative of the minimal potential infectious environmental impact and lack of public health hazard associated with medical waste, we must accept the following: that the pathogens are the same whether they come from the hospital or the community, and that the municipal waste studied contained waste materials we now define as regulated medical waste.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Robotic assisted minimally invasive surgery

    Directory of Open Access Journals (Sweden)

    Palep Jaydeep

    2009-01-01

    Full Text Available The term "robot" was coined by the Czech playright Karel Capek in 1921 in his play Rossom′s Universal Robots. The word "robot" is from the check word robota which means forced labor.The era of robots in surgery commenced in 1994 when the first AESOP (voice controlled camera holder prototype robot was used clinically in 1993 and then marketed as the first surgical robot ever in 1994 by the US FDA. Since then many robot prototypes like the Endoassist (Armstrong Healthcare Ltd., High Wycombe, Buck, UK, FIPS endoarm (Karlsruhe Research Center, Karlsruhe, Germany have been developed to add to the functions of the robot and try and increase its utility. Integrated Surgical Systems (now Intuitive Surgery, Inc. redesigned the SRI Green Telepresence Surgery system and created the daVinci Surgical System ® classified as a master-slave surgical system. It uses true 3-D visualization and EndoWrist ® . It was approved by FDA in July 2000 for general laparoscopic surgery, in November 2002 for mitral valve repair surgery. The da Vinci robot is currently being used in various fields such as urology, general surgery, gynecology, cardio-thoracic, pediatric and ENT surgery. It provides several advantages to conventional laparoscopy such as 3D vision, motion scaling, intuitive movements, visual immersion and tremor filtration. The advent of robotics has increased the use of minimally invasive surgery among laparoscopically naοve surgeons and expanded the repertoire of experienced surgeons to include more advanced and complex reconstructions.

  14. Against Explanatory Minimalism in Psychiatry.

    Science.gov (United States)

    Thornton, Tim

    2015-01-01

    The idea that psychiatry contains, in principle, a series of levels of explanation has been criticized not only as empirically false but also, by Campbell, as unintelligible because it presupposes a discredited pre-Humean view of causation. Campbell's criticism is based on an interventionist-inspired denial that mechanisms and rational connections underpin physical and mental causation, respectively, and hence underpin levels of explanation. These claims echo some superficially similar remarks in Wittgenstein's Zettel. But attention to the context of Wittgenstein's remarks suggests a reason to reject explanatory minimalism in psychiatry and reinstate a Wittgensteinian notion of levels of explanation. Only in a context broader than the one provided by interventionism is that the ascription of propositional attitudes, even in the puzzling case of delusions, justified. Such a view, informed by Wittgenstein, can reconcile the idea that the ascription mental phenomena presupposes a particular level of explanation with the rejection of an a priori claim about its connection to a neurological level of explanation.

  15. Minimal hepatic encephalopathy: A review.

    Science.gov (United States)

    Nardone, Raffaele; Taylor, Alexandra C; Höller, Yvonne; Brigo, Francesco; Lochner, Piergiorgio; Trinka, Eugen

    2016-10-01

    Minimal hepatic encephalopathy (MHE) is the earliest form of hepatic encephalopathy and can affect up to 80% of patients with liver cirrhosis. By definition, MHE is characterized by cognitive function impairment in the domains of attention, vigilance and integrative function, but obvious clinical manifestation are lacking. MHE has been shown to affect daily functioning, quality of life, driving and overall mortality. The diagnosis can be achieved through neuropsychological testing, recently developed computerized psychometric tests, such as the critical flicker frequency and the inhibitory control tests, as well as neurophysiological procedures. Event related potentials can reveal subtle changes in patients with normal neuropsychological performances. Spectral analysis of electroencephalography (EEG) and quantitative analysis of sleep EEG provide early markers of cerebral dysfunction in cirrhotic patients with MHE. Neuroimaging, in particular MRI, also increasingly reveals diffuse abnormalities in intrinsic brain activity and altered organization of functional connectivity networks. Medical treatment for MHE to date has been focused on reducing serum ammonia levels and includes non-absorbable disaccharides, probiotics or rifaximin. Liver transplantation may not reverse the cognitive deficits associated with MHE. We performed here an updated review on epidemiology, burden and quality of life, neuropsychological testing, neuroimaging, neurophysiology and therapy in subjects with MHE.

  16. Unoriented Minimal Type 0 Strings

    CERN Document Server

    Carlisle, J E; Carlisle, James E; Johnson, Clifford V

    2004-01-01

    We define a family of string equations with perturbative expansions that admit an interpretation as an unoriented minimal string theory with background D-branes and R-R fluxes. The theory also has a well-defined non-perturbative sector and we expect it to have a continuum interpretation as an orientifold projection of the non-critical type~0A string for \\hat{c}=0, the (2,4) model. There is a second perturbative region which is consistent with an interpretation in terms of background R-R fluxes. We identify a natural parameter in the formulation that we speculate may have an interpretation as characterizing the contribution of a new type of background D-brane. There is a non-perturbative map to a family of string equations which we expect to be the \\hat{c}=0 type 0B string. The map exchanges D-branes and R-R fluxes. We present the general structure of the string equations for the (2,4k) type 0A models.

  17. Cosine tuning minimizes motor errors.

    Science.gov (United States)

    Todorov, Emanuel

    2002-06-01

    Cosine tuning is ubiquitous in the motor system, yet a satisfying explanation of its origin is lacking. Here we argue that cosine tuning minimizes expected errors in force production, which makes it a natural choice for activating muscles and neurons in the final stages of motor processing. Our results are based on the empirically observed scaling of neuromotor noise, whose standard deviation is a linear function of the mean. Such scaling predicts a reduction of net force errors when redundant actuators pull in the same direction. We confirm this prediction by comparing forces produced with one versus two hands and generalize it across directions. Under the resulting neuromotor noise model, we prove that the optimal activation profile is a (possibly truncated) cosine--for arbitrary dimensionality of the workspace, distribution of force directions, correlated or uncorrelated noise, with or without a separate cocontraction command. The model predicts a negative force bias, truncated cosine tuning at low muscle cocontraction levels, and misalignment of preferred directions and lines of action for nonuniform muscle distributions. All predictions are supported by experimental data.

  18. Study of constrained minimal supersymmetry

    CERN Document Server

    Kane, G L; Roszkowski, Leszek; Wells, J D; Chris Kolda; Leszek Roszkowski; James D Wells

    1994-01-01

    Taking seriously phenomenological indications for supersymmetry, we have made a detailed study of unified minimal SUSY, including effects at the few percent level in a consistent fashion. We report here a general analysis without choosing a particular unification gauge group. We find that the encouraging SUSY unification results of recent years do survive the challenge of a more complete and accurate analysis. Taking into account effects at the 5-10% level leads to several improvements of previous results, and allows us to sharpen our predictions for SUSY in the light of unification. We perform a thorough study of the parameter space. The results form a well-defined basis for comparing the physics potential of different facilities. Very little of the acceptable parameter space has been excluded by LEP or FNAL so far, but a significant fraction can be covered when these accelerators are upgraded. A number of initial applications to the understanding of the SUSY spectrum, detectability of SUSY at LEP II or FNAL...

  19. Irradiation treatment of minimally processed carrots for ensuring microbiological safety

    Energy Technology Data Exchange (ETDEWEB)

    Ashraf Chaudry, Muhammad; Bibi, Nizakat; Khan, Misal; Khan, Maazullah; Badshah, Amal; Jamil Qureshi, Muhammad

    2004-10-01

    Minimally processed fruits and vegetables are very common in developed countries and are gaining popularity in developing countries due to their convenience and freshness. However, minimally processing may result in undesirable changes in colour, taste and appearance due to the transfer of microbes from skin to the flesh. Irradiation is a well-known technology for elimination of microbial contamination. Food irradiation has been approved by 50 countries and is being applied commercially in USA. The purpose of this study was to evaluate the effect of irradiation on the quality of minimally processed carrots. Fresh carrots were peeled, sliced and PE packaged. The samples were irradiated (0, 0.5, 1.0, 2.0, 2.5, 3.0 kGy) and stored at 5 deg. C for 2 weeks. The samples were analyzed for hardness, organoleptic acceptance and microbial load at 0, 7th and 15th day. The mean firmness of the control and all irradiated samples remained between 4.31 and 4.42 kg of force, showing no adverse effect of radiation dose. The effect of storage (2 weeks) was significant (P< 0.05) with values ranging between 4.28 and 4.39 kg of force. The total bacterial counts at 5 deg. C for non-irradiated and 0.5 kGy irradiated samples were 6.3x10{sup 5} cfu/g, 3.0x10{sup 2} and few colonies(>10) in all other irradiated samples(1.0, 2.0, 2.5 and 3.0 kGy) after 2 weeks storage. No coliform or E. coli were detected in any of the samples (radiated or control) immediately after irradiation and during the entire storage period in minimally processed carrots. A dose of 2.0 kGy completely controlled the fungal and bacterial counts. The irradiated samples (2.0 kGy) were also acceptable sensorially.

  20. Noncommutative scalar field minimally coupled to nonsymmetric gravity

    Energy Technology Data Exchange (ETDEWEB)

    Kouadik, S.; Sefai, D. [Laboratory of Mechanic, Physics and Mathematical Modeling Medea University (Algeria)

    2012-06-27

    We construct a non-commutative non symmetric gravity minimally coupled model (the star product only couples matter). We introduce the action for the system considered namely a non-commutative scalar field propagating in a nontrivial gravitational background. We expand the action in powers of the anti-symmetric field and the graviton to second order adopting the assumption that the scalar is weekly coupled to the graviton. We compute the one loop radiative corrections to the self-energy of a scalar particle.

  1. Global regularity for minimal sets and counterexamples

    CERN Document Server

    Liang, Xiangyu

    2011-01-01

    We discuss the global regularity for 2 dimensional minimal sets, that is, whether all global minimal sets in $\\R^n$ are cones or not. Every minimal set looks like a minimal cone $C$ at infinity, hence the main point is to use the topological properties of a minimal set at large scale to control its topology at smaller scales. Such arguments depend on the cone $C$, thus we have to discuss them one by one. Recall that this is the idea to prove that 1-dimensional Almgren-minimal sets in $\\R^n$, and 2-dimensional Mumford-Shah minimal sets in $\\R^3$ are cones. In this article we discuss three types of 2-dimensional minimal sets: Almgren-minimal set in $\\R^3$ whose blow-in limit is a $\\T$ set; topological minimal sets in $\\R^4$ whose blow-in limit is a $\\T$ set; and Almgren minimal sets in $\\R^4$ whose blow-in limit is the union $P_\\theta$ of two almost orthogonal planes. For the first one we eliminate an existing potential counterexample that was proposed by several people, and show that a real counterexample shou...

  2. Simulating seasonal patterns of increased greenhouse crop production by conversion of direct radiation into diffuse radiation

    NARCIS (Netherlands)

    Jongschaap, R.E.E.; Dueck, T.A.; Hemming, S.; Marcelis, L.F.M.; Marissen, A.

    2006-01-01

    The conversion of direct solar photosynthetically active radiation (PARDir) into diffuse radiation (PARDif) and its effects on greenhouse crop production were analyzed with simulation models. PARDir can be converted into PARDif by increasing the haze of greenhouse covers with a minimal loss of radia

  3. Minimal models of multidimensional computations.

    Directory of Open Access Journals (Sweden)

    Jeffrey D Fitzgerald

    2011-03-01

    Full Text Available The multidimensional computations performed by many biological systems are often characterized with limited information about the correlations between inputs and outputs. Given this limitation, our approach is to construct the maximum noise entropy response function of the system, leading to a closed-form and minimally biased model consistent with a given set of constraints on the input/output moments; the result is equivalent to conditional random field models from machine learning. For systems with binary outputs, such as neurons encoding sensory stimuli, the maximum noise entropy models are logistic functions whose arguments depend on the constraints. A constraint on the average output turns the binary maximum noise entropy models into minimum mutual information models, allowing for the calculation of the information content of the constraints and an information theoretic characterization of the system's computations. We use this approach to analyze the nonlinear input/output functions in macaque retina and thalamus; although these systems have been previously shown to be responsive to two input dimensions, the functional form of the response function in this reduced space had not been unambiguously identified. A second order model based on the logistic function is found to be both necessary and sufficient to accurately describe the neural responses to naturalistic stimuli, accounting for an average of 93% of the mutual information with a small number of parameters. Thus, despite the fact that the stimulus is highly non-Gaussian, the vast majority of the information in the neural responses is related to first and second order correlations. Our results suggest a principled and unbiased way to model multidimensional computations and determine the statistics of the inputs that are being encoded in the outputs.

  4. Analysis of several ways to minimize the scatter contribution in radiographic digital images of offshore pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Edmilson M.; Silva, Ademir X.; Lopes, Ricardo T., E-mail: emonteiro@nuclear.ufrj.b, E-mail: ademir@nuclear.ufrj.b, E-mail: Ricardo@lin.ufrj.b [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEN/COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Programa de Engenharia Nuclear; Correa, Samanda C.A., E-mail: scorrea@cnen.gov.b [Comissao Nacional de Energia Nuclear (DIAPI/CGMI/CNEN), Rio de Janeiro, RJ (Brazil). Coordenacao Geral de Instalacoes Medicas e Industriais. Div. de Aplicacoes Industriais

    2011-07-01

    The aim of this work is to evaluate, through MCNPX simulations, several ways to minimize the scatter contribution in radiographic digital images of offshore pipelines. The influence of liquid inside the pipes and water surrounded the pipelines in the scatter contribution will be analyzed. The use of lead screen behind the detector to reduce the backscattered radiation and filter between the radiation source and the pipes will be discussed. (author)

  5. Radiation risk in nuclear medicine.

    Science.gov (United States)

    Adelstein, S James

    2014-05-01

    Given the central roles that anatomical and functional imaging now play in medical practice, there have been concerns about the increasing levels of radiation exposure and their potential hazards. Despite incomplete quantitative knowledge of the risks, it is prudent to think of radiation, even at low doses, as a potential, albeit weak, carcinogen. Thus, we are obliged to minimize its dose and optimize its benefits. Hopefully, time will clarify our estimates of the dangers. Until then, we should educate and assure our patients, their families, and colleagues that the risks have been taken into account and are well balanced by the benefits.

  6. Radiation Hydrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Castor, J I

    2003-10-16

    The discipline of radiation hydrodynamics is the branch of hydrodynamics in which the moving fluid absorbs and emits electromagnetic radiation, and in so doing modifies its dynamical behavior. That is, the net gain or loss of energy by parcels of the fluid material through absorption or emission of radiation are sufficient to change the pressure of the material, and therefore change its motion; alternatively, the net momentum exchange between radiation and matter may alter the motion of the matter directly. Ignoring the radiation contributions to energy and momentum will give a wrong prediction of the hydrodynamic motion when the correct description is radiation hydrodynamics. Of course, there are circumstances when a large quantity of radiation is present, yet can be ignored without causing the model to be in error. This happens when radiation from an exterior source streams through the problem, but the latter is so transparent that the energy and momentum coupling is negligible. Everything we say about radiation hydrodynamics applies equally well to neutrinos and photons (apart from the Einstein relations, specific to bosons), but in almost every area of astrophysics neutrino hydrodynamics is ignored, simply because the systems are exceedingly transparent to neutrinos, even though the energy flux in neutrinos may be substantial. Another place where we can do ''radiation hydrodynamics'' without using any sophisticated theory is deep within stars or other bodies, where the material is so opaque to the radiation that the mean free path of photons is entirely negligible compared with the size of the system, the distance over which any fluid quantity varies, and so on. In this case we can suppose that the radiation is in equilibrium with the matter locally, and its energy, pressure and momentum can be lumped in with those of the rest of the fluid. That is, it is no more necessary to distinguish photons from atoms, nuclei and electrons, than it is

  7. On o-minimal homotopy groups

    CERN Document Server

    Baro, Elias

    2008-01-01

    We work over an o-minimal expansion of a real closed field. The o-minimal homotopy groups of a definable set are defined naturally using definable continuous maps. We prove that any two semialgebraic maps which are definably homotopic are also semialgebraically homotopic. This result together with the study of semialgebraic homotopy done by H. Delfs and M. Knebusch allows us to develop an o-minimal homotopy theory. In particular, we obtain o-minimal versions of the Hurewicz theorems and the Whitehead theorem.

  8. Spacecraft Electrostatic Radiation Shielding

    Science.gov (United States)

    2008-01-01

    This project analyzed the feasibility of placing an electrostatic field around a spacecraft to provide a shield against radiation. The concept was originally proposed in the 1960s and tested on a spacecraft by the Soviet Union in the 1970s. Such tests and analyses showed that this concept is not only feasible but operational. The problem though is that most of this work was aimed at protection from 10- to 100-MeV radiation. We now appreciate that the real problem is 1- to 2-GeV radiation. So, the question is one of scaling, in both energy and size. Can electrostatic shielding be made to work at these high energy levels and can it protect an entire vehicle? After significant analysis and consideration, an electrostatic shield configuration was proposed. The selected architecture was a torus, charged to a high negative voltage, surrounding the vehicle, and a set of positively charged spheres. Van de Graaff generators were proposed as the mechanism to move charge from the vehicle to the torus to generate the fields necessary to protect the spacecraft. This design minimized complexity, residual charge, and structural forces and resolved several concerns raised during the internal critical review. But, it still is not clear if such a system is costeffective or feasible, even though several studies have indicated usefulness for radiation protection at energies lower than that of the galactic cosmic rays. Constructing such a system will require power supplies that can generate voltages 10 times that of the state of the art. Of more concern is the difficulty of maintaining the proper net charge on the entire structure and ensuring that its interaction with solar wind will not cause rapid discharge. Yet, if these concerns can be resolved, such a scheme may provide significant radiation shielding to future vehicles, without the excessive weight or complexity of other active shielding techniques.

  9. Optimization and radiation protection culture

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, In Young; Shin, Hyeong Ki; Lee, Chan Mi [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2013-04-15

    Safety culture or radiation protection culture is based in common on the term, 'culture'. Culture is defined as the learned, shared set of symbols and patterns of basic assumptions, which is invented, discovered, or developed by a given group as it learns to cope with its problem of external adaptation and internal integration. Safety culture generally refers to the attitude and behaviors affecting safety performance. The concept of 'Safety Culture' was introduced after the Chernobyl accident in 1986. For the accident, nuclear society reached the conclusion that the cause was the wrong management attitude of the NPP, that is, deficient 'Safety Culture'. Recently, 'Radiation Protection Culture' was introduced as the core concept of nuclear safety culture. There have been many efforts to establish definition and develop assessment tool for radiation protection culture in international level such as ICRP and IRPA as well as NRC. In the same context with the safety culture, radiation protection culture is defined as 'the core values and behaviors resulting from a collective commitment by leaders and individual's to emphasize safety over competing goals to ensure protection of people and the environment.' It is worthwhile to recognize that regulatory enforcement in establishing healthy radiation protection culture of operators should be minimized because culture is not in the domain of regulatory enforcement. However, as 'ALARA', the most important concept in radiation protection, may be successfully achieved only in well established radiation protection culture, the least regulatory intervention would be needed in promoting and nurturing radiation protection culture in licensee. In addition, the concept of radiation protection culture should be addressed in plant operational policy to achieve the goals of ALARA. The pre-condition of the successful radiation protection culture is a healthy organizational

  10. Radiation Exposure

    Science.gov (United States)

    ... on to any children you have after the exposure. A lot of radiation over a short period, ... skin burns and reduced organ function. If the exposure is large enough, it can cause premature aging ...

  11. Radiation damage

    CERN Document Server

    Heijne, Erik H M; CERN. Geneva

    1998-01-01

    a) Radiation damage in organic materials. This series of lectures will give an overview of radiation effects on materials and components frequently used in accelerator engineering and experiments. Basic degradation phenomena will be presented for organic materials with comprehensive damage threshold doses for commonly used rubbers, thermoplastics, thermosets and composite materials. Some indications will be given for glass, scintillators and optical fibres. b) Radiation effects in semiconductor materials and devices. The major part of the time will be devoted to treat radiation effects in semiconductor sensors and the associated electronics, in particular displacement damage, interface and single event phenomena. Evaluation methods and practical aspects will be shown. Strategies will be developed for the survival of the materials under the expected environmental conditions of the LHC machine and detectors. I will describe profound revolution in our understanding of black holes and their relation to quantum me...

  12. Radiation Transport

    Energy Technology Data Exchange (ETDEWEB)

    Urbatsch, Todd James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-06-15

    We present an overview of radiation transport, covering terminology, blackbody raditation, opacities, Boltzmann transport theory, approximations to the transport equation. Next we introduce several transport methods. We present a section on Caseology, observing transport boundary layers. We briefly broach topics of software development, including verification and validation, and we close with a section on high energy-density experiments that highlight and support radiation transport.

  13. Radiation Protection

    Energy Technology Data Exchange (ETDEWEB)

    Loos, M

    2001-04-01

    Major achievements of SCK-CEN's Radiation Protection Department in 2000 are described. The main areas for R and D of the department remain neutron dosimetry and neutron activation analysis, safeguards information handling and non-destructive assay techniques. Further activities include low-level radioactivity measurements in environmental and biological samples and radiation protection research. Finally, achievements in decision strategy research and social sciences in nuclear research are reported.

  14. Contemporary review of minimally invasive pancreaticoduodenectomy.

    Science.gov (United States)

    Dai, Rui; Turley, Ryan S; Blazer, Dan G

    2016-12-27

    To assess the current literature describing various minimally invasive techniques for and to review short-term outcomes after minimally invasive pancreaticoduodenectomy (PD). PD remains the only potentially curative treatment for periampullary malignancies, including, most commonly, pancreatic adenocarcinoma. Minimally invasive approaches to this complex operation have begun to be increasingly reported in the literature and are purported by some to reduce the historically high morbidity of PD associated with the open technique. In this systematic review, we have searched the literature for high-quality publications describing minimally invasive techniques for PD-including laparoscopic, robotic, and laparoscopic-assisted robotic approaches (hybrid approach). We have identified publications with the largest operative experiences from well-known centers of excellence for this complex procedure. We report primarily short term operative and perioperative results and some short term oncologic endpoints. Minimally invasive techniques include laparoscopic, robotic and hybrid approaches and each of these techniques has strong advocates. Consistently, across all minimally invasive modalities, these techniques are associated less intraoperative blood loss than traditional open PD (OPD), but in exchange for longer operating times. These techniques are relatively equivalent in terms of perioperative morbidity and short term oncologic outcomes. Importantly, pancreatic fistula rate appears to be comparable in most minimally invasive series compared to open technique. Impact of minimally invasive technique on length of stay is mixed compared to some traditional open series. A few series have suggested that initiation of and time to adjuvant therapy may be improved with minimally invasive techniques, however this assertion remains controversial. In terms of short-terms costs, minimally invasive PD is significantly higher than that of OPD. Minimally invasive approaches to PD show

  15. Warm inflation with an oscillatory inflaton in non-minimal kinetic coupling model

    CERN Document Server

    Goodarzi, Parviz

    2016-01-01

    Inflation with an oscillatory inflaton in the non-minimal derivative coupling model is considered. Radiation generation during this era is taken into account. Cosmological perturbations for thermal fluctuation and the temperature at the end of warm oscillatory inflation are computed.

  16. Minimization of Fuzzy Finite Generalized Automata

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Some concepts in Fuzzy Generalized Automata (FGA) are established. Then an important new algorithm which would calculate the minimal FGA is given. The new algorithm is composed of two parts: the first is called E-reduction which contracts equivalent states, and the second is called RE-reduction which removes retrievable states. Finally an example is given to illuminate the algorithm of minimization.

  17. The relative volume growth of minimal submanifolds

    DEFF Research Database (Denmark)

    Markvorsen, Steen; Palmer, V.

    2002-01-01

    The volume growth of certain well-defined subsets of minimal submanifolds in riemannian spaces are compared with the volume growth of balls and spheres ill space forms of constant curvature.......The volume growth of certain well-defined subsets of minimal submanifolds in riemannian spaces are compared with the volume growth of balls and spheres ill space forms of constant curvature....

  18. Minimal Exit Trajectories with Optimum Correctional Manoeuvres

    Directory of Open Access Journals (Sweden)

    T. N. Srivastava

    1980-10-01

    Full Text Available Minimal exit trajectories with optimum correctional manoeuvers to a rocket between two coplaner, noncoaxial elliptic orbits in an inverse square gravitational field have been investigated. Case of trajectories with no correctional manoeuvres has been analysed. In the end minimal exit trajectories through specified orbital terminals are discussed and problem of ref. (2 is derived as a particular case.

  19. Synchrotron radiation with radiation reaction

    Science.gov (United States)

    Nelson, Robert W.; Wasserman, Ira

    1991-04-01

    A rigorous discussion is presented of the classical motion of a relativistic electron in a magnetic field and the resulting electromagnetic radiation when radiation reaction is important. In particular, for an electron injected with initial energy gamma(0), a systematic perturbative solution to the Lorentz-Dirac equation of motion is developed for field strengths satisfying gamma(0) B much less than 6 x 10 to the 15th G. A particularly accurate solution to the electron orbital motion in this regime is found and it is demonstrated how lowest-order corrections can be calculated. It is shown that the total energy-loss rate corresponds to what would be found using the exact Larmor power formula without including radiation reaction. Provided that the particle energy and field strength satisfy the same contraint, it is explicitly demonstrated that the intuitive prescription for calculating the time-integrated radiation spectrum described above is correct.

  20. Abdominal radiation - discharge

    Science.gov (United States)

    Radiation - abdomen - discharge; Cancer - abdominal radiation; Lymphoma - abdominal radiation ... When you have radiation treatment for cancer, your body goes through changes. About 2 weeks after radiation treatment starts, you might notice changes ...

  1. Brain radiation - discharge

    Science.gov (United States)

    Radiation - brain - discharge; Cancer-brain radiation; Lymphoma - brain radiation; Leukemia - brain radiation ... Decadron) while you are getting radiation to the brain. It may make you hungrier, cause leg swelling ...

  2. Trends In Materials Processing With Laser Radiation

    Science.gov (United States)

    Herziger, G.; Kreutz, E. W.

    1989-04-01

    The objectives of reactive chemical and nonreactive thermal processing with laser radiation are outlined giving indication that processing with laser radiation is governed by a hierarchy of time constants originating from photon-matter interaction, phase transition dynamics, laser source excitation fluctuations,, and optical feedback in combination with the influence of beam delivery systems, processing/shielding gas flow configurations, robotics, production lines and environment. The minimization of losses by heat flow, reflection and transmission and the stringent need for quality assurance require as first approach the control of processing, which is mainly due to the capability of laser radiation source. The current status of laser radiation sources is reported giving information on the state of the art of processing with laser radiation in combination with subsequent demonstration of future trends and developments with respect to radiation sources, beam delivery, beam shaping, materials, processing and quality assurance.

  3. Trends in materials processsing with laser radiation

    Science.gov (United States)

    Herziger, Gerd; Kreutz, Ernst W.

    1989-03-01

    The objectives of reactive chemical and nonreactive thermal processing with laser radiation are outlined giving indication that processing with laser radiation is governed by a hierarchy of time constants originating from photon-matter interaction, phase transition dynamics, laser source excitation fluctuations, and optical feedback in combination with the influence of beam delivery systems, processing/shielding gas flow configurations, robotics, production lines and environment. The minimization of losses by heat flow, reflection and transmission and the stringent need for quality assurance require as first approach the control of processing, which is mainly due to the capability of laser radiation source. The current status of laser radiation sources is reported giving information on the state of the art of processing with laser radiation in combination with subsequent demonstration of future trends and developments with respect to radiation sources, beam delivery, beam shaping, materials, processing and quality assurance.

  4. Radiation Environment for the Jupiter Europa Orbiter

    Science.gov (United States)

    Jun, Insoo

    2008-09-01

    One of the major challenges for the Jupiter Europa Orbiter (JEO) mission would be that the spacecraft should be designed to survive an intense radiation environment expected at Jupiter and Europa. The proper definition of the radiation environments is the important first step, because it could affect almost every aspects of mission and spacecraft design. These include optimizing the trajectory to minimize radiation exposure, determining mission lifetime, selecting parts, materials, detectors and sensors, shielding design, etc. The radiation environments generated for the 2008 JEO study will be covered, emphasizing the radiation environment mainly responsible for the total ionizing dose (TID) and displacement damage dose (DDD). The latest models developed at JPL will be used to generate the TID and DDD environments. Finally, the major radiation issues will be summarized, and a mitigation plan will be discussed.

  5. Calibrating a custom-made densitometer for radiation hardness measurements

    CERN Document Server

    Vaananen, Mika Petteri

    2017-01-01

    A custom-made densitometer was set up to be used in radiation hardness measurements of scintillating fibres. Also, a measurement setup to measure the minimal bending radius of scintillating fibres was designed and implemented.

  6. Optical Real-Time Space Radiation Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Real-time dosimetry is needed to provide immediate feedback, so astronauts can minimize their exposure to ionizing radiation during periods of high solar activity....

  7. Radiosensitizers, radioprotectors, and radiation mitigators

    Directory of Open Access Journals (Sweden)

    Jayam Raviraj

    2014-01-01

    Full Text Available Radiotherapy is regarded as one of the most important therapeutic modality for the treatment of malignant lesions. This field is undergoing rapid advancements in the recent times. With the use of radiosensitizers and radioprotective agents, the course of radiotherapy has improved the sensitization of tumor cells and protection of normal cells, respectively. The aim of this paper was to critically review and analyze the available compounds used as radiosensitizers, radioprotectors, and radiation mitigators. For reviewing, the author used the electronic search for the keywords ′Radiosensitizers′, ′Radioprotectors′, ′Radiation mitigators′ on PubMed for inclusion of previously published articles and further search of reference papers on individual radiosensitizing and radioprotecting agents was done. Radiosensitizers are agents that sensitize the tumor cells to radiation. These compounds apparently promote fixation of the free radicals produced by radiation damage at the molecular level. The mechanism of action is similar to the oxygen effect, in which biochemical reactions in the damaged molecules prevent repair of the cellular radiation damage. Free radicals such as OH + are captured by the electron affinity of the radiosensitizers, rendering the molecules incapable of repair. Radioprotectors are compounds that are designed to reduce the damage in normal tissues caused by radiation. These compounds are often antioxidants and must be present before or at the time of radiation for effectiveness. Other agents, termed mitigators, may be used to minimize toxicity even after radiation has been delivered. This article tries to discuss the various aspects of radiosensitizers, radioprotectors, and radiation mitigators including the newer agents.

  8. Green Cellular - Optimizing the Cellular Network for Minimal Emission from Mobile Stations

    CERN Document Server

    Ezri, Doron

    2009-01-01

    Wireless systems, which include cellular phones, have become an essential part of the modern life. However the mounting evidence that cellular radiation might adversely affect the health of its users, leads to a growing concern among authorities and the general public. Radiating antennas in the proximity of the user, such as antennas of mobile phones are of special interest for this matter. In this paper we suggest a new architecture for wireless networks, aiming at minimal emission from mobile stations, without any additional radiation sources. The new architecture, dubbed Green Cellular, abandons the classical transceiver base station design and suggests the augmentation of transceiver base stations with receive only devices. These devices, dubbed Green Antennas, are not aiming at coverage extension but rather at minimizing the emission from mobile stations. We discuss the implications of the Green Cellular architecture on 3G and 4G cellular technologies. We conclude by showing that employing the Green Cell...

  9. Minimal change disease: a CD80 podocytopathy?

    Science.gov (United States)

    Ishimoto, Takuji; Shimada, Michiko; Araya, Carlos E; Huskey, Janna; Garin, Eduardo H; Johnson, Richard J

    2011-07-01

    Minimal change disease is the most common nephrotic syndrome in children. Although the etiology of minimal change disease remains to be elucidated, it has been postulated that it is the result of a circulating T-cell factor that causes podocyte cytoskeleton disorganization leading to increased glomerular capillary permeability and/or changes in glomerular basement membrane heparan sulfate glycosaminoglycans resulting in proteinuria. Minimal change disease has been associated with allergies and Hodgkin disease. Consistent with these associations, a role for interleukin-13 with minimal change disease has been proposed. Furthermore, studies evaluating podocytes also have evolved. Recently, increased expression of CD80 (also termed B7-1) on podocytes was identified as a mechanism for proteinuria. CD80 is inhibited by binding to CTLA-4, which is expressed on regulatory T cells. Recently, we showed that urinary CD80 is increased in minimal change disease patients and limited studies have suggested that it is not commonly present in the urine of patients with other glomerular diseases. Interleukin-13 or microbial products via Toll-like receptors could be factors that induce CD80 expression on podocytes. CTLA-4 appears to regulate CD80 expression in podocytes, and to be altered in minimal change disease patients. These findings lead us to suggest that proteinuria in minimal change disease is caused by persistent CD80 expression in podocytes, possibly initiated by stimulation of these cells by antigens or cytokines.

  10. Theories of minimalism in architecture: Post scriptum

    Directory of Open Access Journals (Sweden)

    Stevanović Vladimir

    2012-01-01

    Full Text Available Owing to the period of intensive development in the last decade of XX century, architectural phenomenon called Minimalism in Architecture was remembered as the Style of the Nineties, which is characterized, morphologically speaking, by simplicity and formal reduction. Simultaneously with its development in practice, on a theoretical level several dominant interpretative models were able to establish themselves. The new millennium and time distance bring new problems; therefore this paper represents a discussion on specific theorization related to Minimalism in Architecture that can bear the designation of post scriptum, because their development starts after the constitutional period of architectural minimalist discourse. In XXI century theories, the problem of definition of minimalism remains important topic, approached by theorists through resolving on the axis: Modernism - Minimal Art - Postmodernism - Minimalism in Architecture. With regard to this, analyzed texts can be categorized in two groups: 1 texts of affirmative nature and historical-associative approach in which minimalism is identified with anything that is simple and reduced, in an idealizing manner, relied mostly on the existing hypotheses; 2 critically oriented texts, in which authors reconsider adequacy of the very term 'minimalism' in the context of architecture and take a metacritical attitude towards previous texts.

  11. Directional radiation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Dowell, Jonathan L.

    2017-09-12

    Directional radiation detectors and systems, methods, and computer-readable media for using directional radiation detectors to locate a radiation source are provided herein. A directional radiation detector includes a radiation sensor. A radiation attenuator partially surrounds the radiation sensor and defines an aperture through which incident radiation is received by the radiation sensor. The aperture is positioned such that when incident radiation is received directly through the aperture and by the radiation sensor, a source of the incident radiation is located within a solid angle defined by the aperture. The radiation sensor senses at least one of alpha particles, beta particles, gamma particles, or neutrons.

  12. Injectable Colloidal Gold in a Sucrose Acetate Isobutyrate Gelating Matrix with Potential Use in Radiation Therapy

    DEFF Research Database (Denmark)

    Jølck, Rasmus Irming; Binderup, Tina; Hansen, Anders Elias

    2014-01-01

    External beam radiation therapy relies on the ability to deliver high radiation doses to tumor cells with minimal exposure to surrounding healthy tissue. Advanced irradiation techniques, including image-guided radiation therapy (IGRT), rely on the ability to locate tumors to optimize the therapeu......External beam radiation therapy relies on the ability to deliver high radiation doses to tumor cells with minimal exposure to surrounding healthy tissue. Advanced irradiation techniques, including image-guided radiation therapy (IGRT), rely on the ability to locate tumors to optimize...

  13. An algorithm for constructing minimal order inverses

    Science.gov (United States)

    Patel, R. V.

    1976-01-01

    In this paper an algorithm is presented for constructing minimal order inverses of linear, time invariant, controllable and observable, multivariable systems. By means of simple matrix operations, a 'state-overdescribed' system is first constructed which is an inverse of the given multivariable system. A simple Gauss-Jordan type reduction procedure is then used to remove the redundancy in the state vector of the inverse system to obtain a minimal order inverse. When the given multivariable system is not invertible, the algorithm enables a minimal order inverse of an invertible subsystem to be constructed. Numerical examples are given to illustrate the use of the algorithm.

  14. Minimal covariant observables identifying all pure states

    Energy Technology Data Exchange (ETDEWEB)

    Carmeli, Claudio, E-mail: claudio.carmeli@gmail.com [D.I.M.E., Università di Genova, Via Cadorna 2, I-17100 Savona (Italy); I.N.F.N., Sezione di Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Heinosaari, Teiko, E-mail: teiko.heinosaari@utu.fi [Turku Centre for Quantum Physics, Department of Physics and Astronomy, University of Turku (Finland); Toigo, Alessandro, E-mail: alessandro.toigo@polimi.it [Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy); I.N.F.N., Sezione di Milano, Via Celoria 16, I-20133 Milano (Italy)

    2013-09-02

    It has been recently shown by Heinosaari, Mazzarella and Wolf (2013) [1] that an observable that identifies all pure states of a d-dimensional quantum system has minimally 4d−4 outcomes or slightly less (the exact number depending on d). However, no simple construction of this type of minimal observable is known. We investigate covariant observables that identify all pure states and have minimal number of outcomes. It is shown that the existence of this kind of observables depends on the dimension of the Hilbert space.

  15. Minimal representations, geometric quantization, and unitarity.

    Science.gov (United States)

    Brylinski, R; Kostant, B

    1994-06-21

    In the framework of geometric quantization we explicitly construct, in a uniform fashion, a unitary minimal representation pio of every simply-connected real Lie group Go such that the maximal compact subgroup of Go has finite center and Go admits some minimal representation. We obtain algebraic and analytic results about pio. We give several results on the algebraic and symplectic geometry of the minimal nilpotent orbits and then "quantize" these results to obtain the corresponding representations. We assume (Lie Go)C is simple.

  16. Laguerre Minimal Surfaces in R3

    Institute of Scientific and Technical Information of China (English)

    Yu Ping SONG; Chang Ping WANG

    2008-01-01

    Laguerre geometry of surfaces in R3 is given in the book of Blaschke,and has been studied by Musso and Nicolodi,Palmer,Li and Wang and other authors.In this paper we study Laguerre minimal surface in 3-dimensional Euclidean space R3.We show that any Laguerre minimal surface in R3 can be constructed by using at most two holomorphic functions.We show also that any Laguerre minimal surface in R3 with constant Laguerre curvature is Laguerre equivalent to a surface with vanishing mean curvature in the 3-dimensional degenerate space R30.

  17. Blackfolds, plane waves and minimal surfaces

    OpenAIRE

    Armas, Jay; Blau, Matthias

    2015-01-01

    Minimal surfaces in Euclidean space provide examples of possible non-compact horizon geometries and topologies in asymptotically flat space-time. On the other hand, the existence of limiting surfaces in the space-time provides a simple mechanism for making these configurations compact. Limiting surfaces appear naturally in a given space-time by making minimal surfaces rotate but they are also inherent to plane wave or de Sitter space-times in which case minimal surfaces can be static and comp...

  18. Minimal free resolutions over complete intersections

    CERN Document Server

    Eisenbud, David

    2016-01-01

    This book introduces a theory of higher matrix factorizations for regular sequences and uses it to describe the minimal free resolutions of high syzygy modules over complete intersections. Such resolutions have attracted attention ever since the elegant construction of the minimal free resolution of the residue field by Tate in 1957. The theory extends the theory of matrix factorizations of a non-zero divisor, initiated by Eisenbud in 1980, which yields a description of the eventual structure of minimal free resolutions over a hypersurface ring. Matrix factorizations have had many other uses in a wide range of mathematical fields, from singularity theory to mathematical physics.

  19. Transience and capacity of minimal submanifolds

    DEFF Research Database (Denmark)

    Markvorsen, Steen; Palmer, V.

    2003-01-01

    We prove explicit lower bounds for the capacity of annular domains of minimal submanifolds P-m in ambient Riemannian spaces N-n with sectional curvatures bounded from above. We characterize the situations in which the lower bounds for the capacity are actually attained. Furthermore we apply...... these bounds to prove that Brownian motion defined on a complete minimal submanifold is transient when the ambient space is a negatively curved Hadamard-Cartan manifold. The proof stems directly from the capacity bounds and also covers the case of minimal submanifolds of dimension m > 2 in Euclidean spaces....

  20. Optimum Location of Thermal Radiation Shield in Superconducting Rotating Machines

    Science.gov (United States)

    Saikiran, P. A.; Rao, V. V.

    2017-02-01

    Superconducting rotating machines have rotor maintained at low temperatures, below the critical temperature of the superconductor. This establishes large temperature difference between the cold rotor and surroundings, resulting in large heat leak into rotor through conduction, convection and radiation. Minimizing this heat leak is essential to reduce the power expense of cryogenic cooling system. A radiation shield is anchored at a suitable location on torque tube to minimize the radiation heat leak into the cold rotor. This paper presents a methodology to determine the optimum location of this anchor-point of radiation shield for a given geometry, which minimizes the total heat leak into cold rotor. The location of radiation shield is found to be depending on emissivity of cold rotor.

  1. Cherenkov radiation; La radiation Cerenkov

    Energy Technology Data Exchange (ETDEWEB)

    Hubert, P. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1955-07-01

    When the radioactivity has been discovered, it was observed by researchers that different materials as mineral salts or solutions were emitting a weak light when submitted to radioactivity beams. At the beginning it has been thought that it was fluorescent light. In 1934, Cherenkov, a russian physicist, worked on the luminescence of uranyl salts solutions caused by gamma radiation and observed a very weak light was emitted by pure liquid. After further studies, he concluded that this phenomena was different from fluorescence. Since then, it has been called Cherenkov effect. This blue light emission is produced when charged particles are going through a transparent medium with an upper velocity than light velocity. This can happen only in medium with large refractive index as water or glass. It also presents its different properties discovered afterwards. The different applications of the Cherenkov radiation are discussed as counting techniques for radiation detectors or comic ray detectors. (M.P.)

  2. Minimal Reductions and Cores of Edge Ideals

    CERN Document Server

    Fouli, Louiza

    2010-01-01

    We study minimal reductions of edge ideals of graphs containing a unique even cycle, and determine restrictions on the coefficients of the generators of these minimal reductions. We focus our attention on two special subclasses of edge ideals; the first is edge ideals of even cycles and the second is edge ideals of even cycles with an arbitrary number of whiskers. We prove that $\\rm{core}(I)=\\mathfrak{m} I$, where $I$ is the edge ideal in the corresponding localized polynomial ring and $\\mathfrak{m}$ is the maximal ideal of this ring. Moreover, we show that the core is obtained as a finite intersection of homogeneous minimal reductions in the case of even cycles. The formula for the core does not hold in general for the edge ideal of any graph and we provide a counterexample. In particular, we show in this example that the core is not obtained as a finite intersection of general minimal reductions.

  3. Minimal regular 2-graphs and applications

    Institute of Scientific and Technical Information of China (English)

    FAN; Hongbing; LIU; Guizhen; LIU; Jiping

    2006-01-01

    A 2-graph is a hypergraph with edge sizes of at most two. A regular 2-graph is said to be minimal if it does not contain a proper regular factor. Let f2(n) be the maximum value of degrees over all minimal regular 2-graphs of n vertices. In this paper, we provide a structure property of minimal regular 2-graphs, and consequently, prove that f2(n) = n+3-i/3where 1 ≤i≤6, i=n (mod 6) andn≥ 7, which solves a conjecture posed by Fan, Liu, Wu and Wong. As applications in graph theory, we are able to characterize unfactorable regular graphs and provide the best possible factor existence theorem on degree conditions. Moreover, f2(n) and the minimal 2-graphs can be used in the universal switch box designs, which originally motivated this study.

  4. Waste minimization and pollution prevention awareness plan

    Energy Technology Data Exchange (ETDEWEB)

    1991-05-31

    The purpose of this plan is to document the Lawrence Livermore National Laboratory (LLNL) Waste Minimization and Pollution Prevention Awareness Program. The plan specifies those activities and methods that are or will be employed to reduce the quantity and toxicity of wastes generated at the site. The intent of this plan is to respond to and comply with (DOE's) policy and guidelines concerning the need for pollution prevention. The Plan is composed of a LLNL Waste Minimization and Pollution Prevention Awareness Program Plan and, as attachments, Program- and Department-specific waste minimization plans. This format reflects the fact that waste minimization is considered a line management responsibility and is to be addressed by each of the Programs and Departments. 14 refs.

  5. Minimally Invasive Transcatheter Aortic Valve Replacement (TAVR)

    Medline Plus

    Full Text Available Watch a Broward Health surgeon perform a minimally invasive Transcatheter Aortic Valve Replacement (TAVR) Click Here to view the BroadcastMed, Inc. Privacy Policy and Legal Notice © 2017 BroadcastMed, Inc. ...

  6. Biharmonic Maps and Laguerre Minimal Surfaces

    Directory of Open Access Journals (Sweden)

    Yusuf Abu Muhanna

    2013-01-01

    Full Text Available A Laguerre surface is known to be minimal if and only if its corresponding isotropic map is biharmonic. For every Laguerre surface Φ is its associated surface Ψ=1+u2Φ, where u lies in the unit disk. In this paper, the projection of the surface Ψ associated to a Laguerre minimal surface is shown to be biharmonic. A complete characterization of Ψ is obtained under the assumption that the corresponding isotropic map of the Laguerre minimal surface is harmonic. A sufficient and necessary condition is also derived for Ψ to be a graph. Estimates of the Gaussian curvature to the Laguerre minimal surface are obtained, and several illustrative examples are given.

  7. Proton Decay in Minimal Supersymmetric SU(5)

    OpenAIRE

    Bajc, Borut; Perez, Pavel Fileviez; Senjanovic, Goran

    2002-01-01

    We systematically study proton decay in the minimal supersymmetric SU(5) grand unified theory. We find that although the available parameter space of soft masses and mixings is quite constrained, the theory is still in accord with experiment.

  8. Global minimizers of coexistence for competing species

    OpenAIRE

    2010-01-01

    A class of variational models describing ecological systems of k species competing for the same resources is investigated. The occurrence of coexistence in minimal energy solutions is discussed and positive results are proven for suitably differentiated internal dynamics.

  9. Genetic algorithms for minimal source reconstructions

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, P.S.; Mosher, J.C.

    1993-12-01

    Under-determined linear inverse problems arise in applications in which signals must be estimated from insufficient data. In these problems the number of potentially active sources is greater than the number of observations. In many situations, it is desirable to find a minimal source solution. This can be accomplished by minimizing a cost function that accounts from both the compatibility of the solution with the observations and for its ``sparseness``. Minimizing functions of this form can be a difficult optimization problem. Genetic algorithms are a relatively new and robust approach to the solution of difficult optimization problems, providing a global framework that is not dependent on local continuity or on explicit starting values. In this paper, the authors describe the use of genetic algorithms to find minimal source solutions, using as an example a simulation inspired by the reconstruction of neural currents in the human brain from magnetoencephalographic (MEG) measurements.

  10. Cigarette price minimization strategies used by adults

    National Research Council Canada - National Science Library

    Pesko, Michael F; Kruger, Judy; Hyland, Andrew

    2012-01-01

    .... We explored use of cigarette price minimization strategies, such as purchasing cartons of cigarettes, purchasing in states with lower after-tax cigarette prices, and purchasing on the Internet...

  11. Minimally Invasive Transcatheter Aortic Valve Replacement (TAVR)

    Medline Plus

    Full Text Available Watch a Broward Health surgeon perform a minimally invasive Transcatheter Aortic Valve Replacement (TAVR) Click Here to view the BroadcastMed, Inc. Privacy Policy and Legal Notice © 2017 BroadcastMed, Inc. ...

  12. Minimally processed fruit salad enriched with Lactobacillus ...

    African Journals Online (AJOL)

    paula

    2015-06-17

    Jun 17, 2015 ... compounds in the preservation of color ... of probiotic microorganisms in minimally processed fruit. (Rößle et al., 2010a, b; ... MATERIALS AND METHODS ..... (2009). The use of packaging techniques to maintain freshness in.

  13. Minimally Invasive Osteotomies of the Calcaneus.

    Science.gov (United States)

    Guyton, Gregory P

    2016-09-01

    Osteotomies of the calcaneus are powerful surgical tools, representing a critical component of the surgical reconstruction of pes planus and pes cavus deformity. Modern minimally invasive calcaneal osteotomies can be performed safely with a burr through a lateral incision. Although greater kerf is generated with the burr, the effect is modest, can be minimized, and is compatible with many fixation techniques. A hinged jig renders the procedure more reproducible and accessible. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Minimal Braid in Applied Symbolic Dynamics

    Institute of Scientific and Technical Information of China (English)

    张成; 张亚刚; 彭守礼

    2003-01-01

    Based on the minimal braid assumption, three-dimensional periodic flows of a dynamical system are reconstructed in the case of unimodal map, and their topological structures are compared with those of the periodic orbits of the Rossler system in phase space through the numerical experiment. The numerical results justify the validity of the minimal braid assumption which provides a suspension from one-dimensional symbolic dynamics in the Poincare section to the knots of three-dimensional periodic flows.

  15. On Quantum Channel Estimation with Minimal Resources

    CERN Document Server

    Zorzi, M; Ferrante, A

    2011-01-01

    We determine the minimal experimental resources that ensure a unique solution in the estimation of trace-preserving quantum channels with both direct and convex optimization methods. A convenient parametrization of the constrained set is used to develop a globally converging Newton-type algorithm that ensures a physically admissible solution to the problem. Numerical simulations are provided to support the results, and indicate that the minimal experimental setting is sufficient to guarantee good estimates.

  16. Minimally Invasive Forefoot Surgery in France.

    Science.gov (United States)

    Meusnier, Tristan; Mukish, Prikesht

    2016-06-01

    Study groups have been formed in France to advance the use of minimally invasive surgery. These techniques are becoming more frequently used and the technique nuances are continuing to evolve. The objective of this article was to advance the awareness of the current trends in minimally invasive surgery for common diseases of the forefoot. The percutaneous surgery at the forefoot is less developed at this time, but also will be discussed.

  17. Ill-Posedness of sublinear minimization problems

    Directory of Open Access Journals (Sweden)

    S. Issa

    2011-04-01

    Full Text Available It is well known that minimization problems involving sublinear regularization terms are ill-posed, in Sobolev spaces. Extended results to spaces of bounded variation functions BV were recently showed in the special case of bounded regularization terms. In this note, a generalization to sublinear regularization is presented in BV spaces. Notice that our results are optimal in the sense that linear regularization leads to well-posed minimization problems in BV spaces.

  18. Lectures on flips and minimal models

    OpenAIRE

    Corti, Alessio; Hacking, Paul; Kollár, János; Lazarsfeld, Robert; Mustaţă, Mircea

    2007-01-01

    This document contains notes from the lectures of Corti, Koll\\'ar, Lazarsfeld, and Musta\\c{t}\\u{a} at the workshop ``Minimal and canonical models in algebraic geometry" at MSRI, Berkeley, April 2007. The lectures give an overview of the recent advances on canonical and minimal models of algebraic varieties obtained by Hacon--McKernan and Birkar--Cascini--Hacon--McKernan.

  19. Two tractable subclasses of minimal unsatisfiable formulas

    Institute of Scientific and Technical Information of China (English)

    赵希顺; 丁德成

    1999-01-01

    The minimal unsatisfiability problem is considered of the propositional formulas in CNF which in the case of variables x1,…, xn consist of n+k clauses including x1V…Vxn and (?) -(X1)V…V(?)xn. It is shown that when k≤4 the minimal unsatisfiability problem can be solved in polynomial time.

  20. The advantages of minimally invasive dentistry.

    Science.gov (United States)

    Christensen, Gordon J

    2005-11-01

    Minimally invasive dentistry, in cases in which it is appropriate, is a concept that preserves dentitions and supporting structures. In this column, I have discussed several examples of minimally invasive dental techniques. This type of dentistry is gratifying for dentists and appreciated by patients. If more dentists would practice it, the dental profession could enhance the public's perception of its honesty and increase its professionalism as well.

  1. L1-norm minimization for quaternion signals

    CERN Document Server

    Wu, Jiasong; Wang, Xiaoqing; Senhadji, Lotfi; Shu, Huazhong

    2012-01-01

    The l1-norm minimization problem plays an important role in the compressed sensing (CS) theory. We present in this letter an algorithm for solving the problem of l1-norm minimization for quaternion signals by converting it to second-order cone programming. An application example of the proposed algorithm is also given for practical guidelines of perfect recovery of quaternion signals. The proposed algorithm may find its potential application when CS theory meets the quaternion signal processing.

  2. Radiation Technology Against Bioterrorism

    Science.gov (United States)

    2004-10-25

    application of radiation processing: radiation crosslinking of polymers and radiation sterilization of health care products have developed into substantial...municipal waste water, • radiation inactivation of bioterrorism agents, • electron beam processing of flue gases, • radiation crosslinking , • radiation...Electron beam processing of flue gases 6. Radiation crosslinking 7. Radiation curing 3 Radiation Technology Against Bioterrorism L.G. Gazsó and G

  3. Minimalism in Art, Medical Science and Neurosurgery.

    Science.gov (United States)

    Ökten, Ali İhsan

    2016-12-21

    The word ''minimalism'' is a word derived from French the word ''minimum''. Whereas the lexical meaning of minimum is ''the least or the smallest quantity necessary for something'', its expression in mathematics can be described as ''the lowest step a variable number can descend, least, minimal''. Minimalism, which advocates an extreme simplicity of the artistic form, is a current in modern art and music whose origins go to 1960s and which features simplicity and objectivity. Although art, science and philosophy are different disciplines, they support each other from time to time, sometimes they intertwine and sometimes they copy each other. A periodic schools or teaching in one of them can take the others into itself, so, they proceed on their ways empowering each other. It is also true for the minimalism in art and the minimal invasive surgical approaches in science. Concepts like doing with less, avoiding unnecessary materials and reducing the number of the elements in order to increase the effect in the expression which are the main elements of the minimalism in art found their equivalents in medicine and neurosurgery. Their equivalents in medicine or neurosurgery have been to protect the physical integrity of the patient with less iatrogenic injury, minimum damage and the same therapeutic effect in the most effective way and to enable the patient to regain his health in the shortest span of time.

  4. Economic impact of minimally invasive lumbar surgery

    Science.gov (United States)

    Hofstetter, Christoph P; Hofer, Anna S; Wang, Michael Y

    2015-01-01

    Cost effectiveness has been demonstrated for traditional lumbar discectomy, lumbar laminectomy as well as for instrumented and noninstrumented arthrodesis. While emerging evidence suggests that minimally invasive spine surgery reduces morbidity, duration of hospitalization, and accelerates return to activites of daily living, data regarding cost effectiveness of these novel techniques is limited. The current study analyzes all available data on minimally invasive techniques for lumbar discectomy, decompression, short-segment fusion and deformity surgery. In general, minimally invasive spine procedures appear to hold promise in quicker patient recovery times and earlier return to work. Thus, minimally invasive lumbar spine surgery appears to have the potential to be a cost-effective intervention. Moreover, novel less invasive procedures are less destabilizing and may therefore be utilized in certain indications that traditionally required arthrodesis procedures. However, there is a lack of studies analyzing the economic impact of minimally invasive spine surgery. Future studies are necessary to confirm the durability and further define indications for minimally invasive lumbar spine procedures. PMID:25793159

  5. Dark Radiative Inverse Seesaw

    CERN Document Server

    Ahriche, Amine; Nasri, Salah

    2016-01-01

    We present a minimal model that simultaneously accounts for neutrino masses and the origin of dark matter (DM) and where the electroweak phase transition is strong enough to allow for electroweak baryogenesis. The Standard Model is enlarged with a Majorana fermion, three generations of chiral fermion pairs, and a single complex scalar that plays a central role in DM production and phenomenology, neutrino masses, and the strength of the phase transition. All the new fields are singlets under the SM gauge group. Neutrino masses are generated via a new variant of radiative inverse seesaw where the required small mass term is generated via loops involving DM and no large hierarchy is assumed among the mass scales. The model offers all the advantage of low-scale neutrino mass models as well as a viable dark matter candidate that is testable with direct detection experiments.

  6. Radiative cooling for thermophotovoltaic systems

    Science.gov (United States)

    Zhou, Zhiguang; Sun, Xingshu; Bermel, Peter

    2016-09-01

    Radiative cooling has recently garnered a great deal of attention for its potential as an alternative method for photovoltaic thermal management. Here, we will consider the limits of radiative cooling for thermal management of electronics broadly, as well as a specific application to thermal power generation. We show that radiative cooling power can increase rapidly with temperature, and is particularly beneficial in systems lacking standard convective cooling. This finding indicates that systems previously operating at elevated temperatures (e.g., 80°C) can be passively cooled close to ambient under appropriate conditions with a reasonable cooling area. To examine these general principles for a previously unexplored application, we consider the problem of thermophotovoltaic (TPV) conversion of heat to electricity via thermal radiation illuminating a photovoltaic diode. Since TPV systems generally operate in vacuum, convective cooling is sharply limited, but radiative cooling can be implemented with proper choice of materials and structures. In this work, realistic simulations of system performance are performed using the rigorous coupled wave analysis (RCWA) techniques to capture thermal emitter radiation, PV diode absorption, and radiative cooling. We subsequently optimize the structural geometry within realistic design constraints to find the best configurations to minimize operating temperature. It is found that low-iron soda-lime glass can potentially cool the PV diode by a substantial amount, even to below ambient temperatures. The cooling effect can be further improved by adding 2D-periodic photonic crystal structures. We find that the improvement of efficiency can be as much as an 18% relative increase, relative to the non-radiatively cooled baseline, as well as a potentially significant improvement in PV diode lifetime.

  7. Minimally doubled fermions at one-loop level

    CERN Document Server

    Capitani, Stefano; Wittig, Hartmut

    2009-01-01

    Single fermionic degrees of freedom together with standard chiral symmetry at finite lattice spacing, correct continuum limit and local interactions only are precluded by the Nielsen-Ninomiya no-go theorem. The class of minimally doubled fermion actions exhibits exactly two chiral modes. Recent interest in these actions has been sparked by the investigation of fermionic actions defined on "hyperdiamond" lattices. Due to the necessity of breaking hypercubic symmetry explicitly, radiative corrections generate operator mixings with relevant and marginal operators that should vanish in continuum QCD. These cannot be avoided and must be taken into account in particular by a peculiar wave-function renormalisation and additive momentum renormalisation. Renormalisation properties at one-loop level of the self-energy, local bilinears and conserved vector and axial-vector currents are presented for Borici-Creutz and Karsten-Wilczek actions. Distinct differences and similarities between both actions are elucidated.

  8. Cosmological model with non-minimally coupled fermionic field

    CERN Document Server

    Ribas, M O; Kremer, G M

    2007-01-01

    A model for the Universe is proposed whose constituents are: (a) a dark energy field modeled by a fermionic field non-minimally coupled with the gravitational field, (b) a matter field which consists of pressureless baryonic and dark matter fields and (c) a field which represents the radiation and the neutrinos. The coupled system of Dirac's equations and Einstein field equations is solved numerically by considering a spatially flat homogeneous and isotropic Universe. It is shown that the proposed model can reproduce the expected red-shift behaviors of the deceleration parameter, of the density parameters of each constituent and of the luminosity distance. Furthermore, for small values of the red-shift the constant which couples the fermionic and gravitational fields has a remarkable influence on the density and deceleration parameters.

  9. Minimal supersymmetric hybrid inflation, flipped SU(5) and proton decay

    Energy Technology Data Exchange (ETDEWEB)

    Rehman, Mansoor Ur; Shafi, Qaisar [Bartol Research Institute, Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States); Wickman, Joshua R., E-mail: jwickman@udel.ed [Bartol Research Institute, Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States)

    2010-04-26

    Minimal supersymmetric hybrid inflation utilizes a canonical Kaehler potential and a renormalizable superpotential which is uniquely determined by imposing a U(1) R-symmetry. In computing the scalar spectral index n{sub s} we take into account modifications of the tree level potential caused by radiative and supergravity corrections, as well as contributions from the soft supersymmetry breaking terms with a negative soft mass-squared term allowed for the inflaton. All of these contributions play a role in realizing n{sub s} values in the range 0.96-0.97 preferred by WMAP. The U(1) R-symmetry plays an important role in flipped SU(5) by eliminating the troublesome dimension five proton decay. The proton decays into e{sup +}pi{sup 0} via dimension six operators arising from the exchange of superheavy gauge bosons with a lifetime of order 10{sup 34}-10{sup 36} years.

  10. Large top and bottom Yukawa couplings in minimal supersymmetry

    CERN Document Server

    Floratos, Emmanuel G

    1994-01-01

    ABSTRACT We present analytic expressions for the top and bottom Yukawa couplings in the context of the minimal supersymmetric standard model when both couplings h_{t,0},h_{b,0} are large at the unification scale. For sufficiently large h_{t,0},h_{b,0}, using as input the central value of the bottom mass m_b(m_b)=4.25GeV, we find that the top mass lies in the range m_t \\approx (174-178)GeV, while tan\\beta \\approx (55-58). Implications on the evolution of the scalar masses and the radiative symmetry breaking scenario are discussed.

  11. Sequential unconstrained minimization algorithms for constrained optimization

    Science.gov (United States)

    Byrne, Charles

    2008-02-01

    The problem of minimizing a function f(x):RJ → R, subject to constraints on the vector variable x, occurs frequently in inverse problems. Even without constraints, finding a minimizer of f(x) may require iterative methods. We consider here a general class of iterative algorithms that find a solution to the constrained minimization problem as the limit of a sequence of vectors, each solving an unconstrained minimization problem. Our sequential unconstrained minimization algorithm (SUMMA) is an iterative procedure for constrained minimization. At the kth step we minimize the function G_k(x)=f(x)+g_k(x), to obtain xk. The auxiliary functions gk(x):D ⊆ RJ → R+ are nonnegative on the set D, each xk is assumed to lie within D, and the objective is to minimize the continuous function f:RJ → R over x in the set C=\\overline D , the closure of D. We assume that such minimizers exist, and denote one such by \\hat x . We assume that the functions gk(x) satisfy the inequalities 0\\leq g_k(x)\\leq G_{k-1}(x)-G_{k-1}(x^{k-1}), for k = 2, 3, .... Using this assumption, we show that the sequence {f(xk)} is decreasing and converges to f({\\hat x}) . If the restriction of f(x) to D has bounded level sets, which happens if \\hat x is unique and f(x) is closed, proper and convex, then the sequence {xk} is bounded, and f(x^*)=f({\\hat x}) , for any cluster point x*. Therefore, if \\hat x is unique, x^*={\\hat x} and \\{x^k\\}\\rightarrow {\\hat x} . When \\hat x is not unique, convergence can still be obtained, in particular cases. The SUMMA includes, as particular cases, the well-known barrier- and penalty-function methods, the simultaneous multiplicative algebraic reconstruction technique (SMART), the proximal minimization algorithm of Censor and Zenios, the entropic proximal methods of Teboulle, as well as certain cases of gradient descent and the Newton-Raphson method. The proof techniques used for SUMMA can be extended to obtain related results for the induced proximal

  12. Smart Radiation Therapy Biomaterials.

    Science.gov (United States)

    Ngwa, Wilfred; Boateng, Francis; Kumar, Rajiv; Irvine, Darrell J; Formenti, Silvia; Ngoma, Twalib; Herskind, Carsten; Veldwijk, Marlon R; Hildenbrand, Georg Lars; Hausmann, Michael; Wenz, Frederik; Hesser, Juergen

    2017-03-01

    Radiation therapy (RT) is a crucial component of cancer care, used in the treatment of over 50% of cancer patients. Patients undergoing image guided RT or brachytherapy routinely have inert RT biomaterials implanted into their tumors. The single function of these RT biomaterials is to ensure geometric accuracy during treatment. Recent studies have proposed that the inert biomaterials could be upgraded to "smart" RT biomaterials, designed to do more than 1 function. Such smart biomaterials include next-generation fiducial markers, brachytherapy spacers, and balloon applicators, designed to respond to stimuli and perform additional desirable functions like controlled delivery of therapy-enhancing payloads directly into the tumor subvolume while minimizing normal tissue toxicities. More broadly, smart RT biomaterials may include functionalized nanoparticles that can be activated to boost RT efficacy. This work reviews the rationale for smart RT biomaterials, the state of the art in this emerging cross-disciplinary research area, challenges and opportunities for further research and development, and a purview of potential clinical applications. Applications covered include using smart RT biomaterials for boosting cancer therapy with minimal side effects, combining RT with immunotherapy or chemotherapy, reducing treatment time or health care costs, and other incipient applications. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Minimal Invasive Urologic Surgery and Postoperative Ileus

    Directory of Open Access Journals (Sweden)

    Fouad Aoun

    2015-07-01

    Full Text Available Postoperative ileus (POI is the most common cause of prolonged length of hospital stays (LOS and associated healthcare costs. The advent of minimal invasive technique was a major breakthrough in the urologic landscape with great potential to progress in the future. In the field of gastrointestinal surgery, several studies had reported lower incidence rates for POI following minimal invasive surgery compared to conventional open procedures. In contrast, little is known about the effect of minimal invasive approach on the recovery of bowel motility after urologic surgery. We performed an overview of the potential benefit of minimal invasive approach on POI for urologic procedures. The mechanisms and risk factors responsible for the onset of POI are discussed with emphasis on the advantages of minimal invasive approach. In the urologic field, POI is the main complication following radical cystectomy but it is rarely of clinical significance for other minimal invasive interventions. Laparoscopy or robotic assisted laparoscopic techniques when studied individually may reduce to their own the duration and prevent the onset of POI in a subset of procedures. The potential influence of age and urinary diversion type on postoperative ileus is contradictory in the literature. There is some evidence suggesting that BMI, blood loss, urinary extravasation, existence of a major complication, bowel resection, operative time and transperitoneal approach are independent risk factors for POI. Treatment of POI remains elusive. One of the most important and effective management strategies for patients undergoing radical cystectomy has been the development and use of enhanced recovery programs. An optimal rational strategy to shorten the duration of POI should incorporate minimal invasive approach when appropriate into multimodal fast track programs designed to reduce POI and shorten LOS.

  14. Cone positioning device for oral radiation therapy.

    Science.gov (United States)

    Mahanna, G K; Ivanhoe, J R; Attanasio, R A

    1994-06-01

    This article describes the fabrication and modification of a peroral cone-positioning device. The modification provides added cone stability and prevents tongue intrusion into the radiation field. This device provides a repeatable accurate cone/lesion relationship and the fabrication technique is simplified, accurate, and minimizes patient discomfort.

  15. Space Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Corliss, William R.

    1968-01-01

    This booklet discusses three kinds of space radiation, cosmic rays, Van Allen Belts, and solar plasma. Cosmic rays are penetrating particles that we cannot see, hear or feel, which come from distant stars. Van Allen Belts, named after their discoverer are great belts of protons and electrons that the earth has captured in its magnetic trap. Solar plasma is a gaseous, electrically neutral mixture of positive and negative ions that the sun spews out from convulsed regions on its surface.

  16. Radiation protection

    CERN Multimedia

    Radioactive Shipping Service

    2005-01-01

    The section of the radiation protection group in charge of shipping radioactive material would like to remind users that all radioactive material leaving CERN must be checked for radioactivity and must be shipped according to the procedure given at http://cern.ch/service-rp-shipping Do not hesitate to contact us for any question or control. Radioactive Shipping Service: service-rp-shipping@cern.ch Tél. 73171

  17. Radiation protection

    CERN Document Server

    2005-01-01

    The section of the Radiation Protection Group in charge of shipping radioactive material would like to remind users that all radioactive material leaving CERN must be checked for radioactivity and must be shipped according to the procedure given at http://cern.ch/service-rp-shipping Do not hesitate to contact us for any question or control. Radioactive Shipping Service: service-rp-shipping@cern.ch Tel. 73171

  18. Radiation protection

    CERN Multimedia

    2005-01-01

    The section of the Radiation Protection Group in charge of shipping radioactive material would like to remind users that all radioactive material leaving CERN must be checked for radioactivity and must be shipped according to the procedure given at http://cern.ch/service-rp-shipping Do not hesitate to contact us for any question or control. Radioactive Shipping Service: service-rp-shipping@cern.ch Tél. 73171

  19. Affordable CZT SPECT with dose-time minimization (Conference Presentation)

    Science.gov (United States)

    Hugg, James W.; Harris, Brian W.; Radley, Ian

    2017-03-01

    PURPOSE Pixelated CdZnTe (CZT) detector arrays are used in molecular imaging applications that can enable precision medicine, including small-animal SPECT, cardiac SPECT, molecular breast imaging (MBI), and general purpose SPECT. The interplay of gamma camera, collimator, gantry motion, and image reconstruction determines image quality and dose-time-FOV tradeoffs. Both dose and exam time can be minimized without compromising diagnostic content. METHODS Integration of pixelated CZT detectors with advanced ASICs and readout electronics improves system performance. Because historically CZT was expensive, the first clinical applications were limited to small FOV. Radiation doses were initially high and exam times long. Advances have significantly improved efficiency of CZT-based molecular imaging systems and the cost has steadily declined. We have built a general purpose SPECT system using our 40 cm x 53 cm CZT gamma camera with 2 mm pixel pitch and characterized system performance. RESULTS Compared to NaI scintillator gamma cameras: intrinsic spatial resolution improved from 3.8 mm to 2.0 mm; energy resolution improved from 9.8% to molecular imaging, coupled with optimal collimator and image reconstruction, result in minimized dose and exam time. With CZT cost improving, affordable whole-body CZT general purpose SPECT is expected to enable precision medicine applications.

  20. Radiatively Generated $\

    CERN Document Server

    Joshipura, A S; Joshipura, Anjan S.; Rindani, Saurabh D.

    2003-01-01

    We study the consequences of assuming that the mass scale $\\Delta_{odot}$ corresponding to the solar neutrino oscillations and mixing angle $U_{e3}$ corresponding to the electron neutrino oscillation at CHOOZ are radiatively generated through the standard electroweak gauge interactions. All the leptonic mass matrices having zero $\\Delta_{odot}$ and $U_{e3}$ at a high scale lead to a unique low energy value for the $\\Delta_{odot}$ which is determined by the (known) size of the radiative corrections, solar and the atmospheric mixing angle and the Majorana mass of the neutrino observed in neutrinoless double beta decay. This prediction leads to the following consequences: ($i$) The MSSM radiative corrections generate only the dark side of the solar neutrino solutions. ($ii$) The inverted mass hierarchy ($m,-m,0$) at the high scale fails in generating the LMA solution but it can lead to the LOW or vacuum solutions. ($iii$) The $\\Delta_{odot}$ generated in models with maximal solar mixing at a high scale is zero t...

  1. Radiation Engineering for Designers

    Science.gov (United States)

    Pellish, Jonathan A.

    2015-01-01

    This tutorial provides an overview of the natural space radiation environment, an introduction to radiation effect types, an overview of EEE parts selection, scrubbing, and radiation mitigation, and an introduction to radiation testing.

  2. Acute Radiation Syndrome

    Science.gov (United States)

    ... Matters Information on Specific Types of Emergencies Acute Radiation Syndrome (ARS): A Fact Sheet for the Public ... is called the radiation dose. People exposed to radiation will get ARS only if: The radiation dose ...

  3. Chest radiation - discharge

    Science.gov (United States)

    Radiation - chest - discharge; Cancer - chest radiation; Lymphoma - chest radiation ... When you have radiation treatment for cancer, your body goes through changes. About 2 weeks after your first treatment: It may be hard ...

  4. Risk Factors: Radiation

    Science.gov (United States)

    Radiation of certain wavelengths, called ionizing radiation, has enough energy to damage DNA and cause cancer. Ionizing radiation includes radon, x-rays, gamma rays, and other forms of high-energy radiation.

  5. Radiation Engineering for Designers

    Science.gov (United States)

    Pellish, Jonathan A.

    2015-01-01

    This tutorial provides an overview of the natural space radiation environment, an introduction to radiation effect types, an overview of EEE parts selection, scrubbing, and radiation mitigation, and an introduction to radiation testing.

  6. Minimally invasive procedures on the lumbar spine

    Science.gov (United States)

    Skovrlj, Branko; Gilligan, Jeffrey; Cutler, Holt S; Qureshi, Sheeraz A

    2015-01-01

    Degenerative disease of the lumbar spine is a common and increasingly prevalent condition that is often implicated as the primary reason for chronic low back pain and the leading cause of disability in the western world. Surgical management of lumbar degenerative disease has historically been approached by way of open surgical procedures aimed at decompressing and/or stabilizing the lumbar spine. Advances in technology and surgical instrumentation have led to minimally invasive surgical techniques being developed and increasingly used in the treatment of lumbar degenerative disease. Compared to the traditional open spine surgery, minimally invasive techniques require smaller incisions and decrease approach-related morbidity by avoiding muscle crush injury by self-retaining retractors, preventing the disruption of tendon attachment sites of important muscles at the spinous processes, using known anatomic neurovascular and muscle planes, and minimizing collateral soft-tissue injury by limiting the width of the surgical corridor. The theoretical benefits of minimally invasive surgery over traditional open surgery include reduced blood loss, decreased postoperative pain and narcotics use, shorter hospital length of stay, faster recover and quicker return to work and normal activity. This paper describes the different minimally invasive techniques that are currently available for the treatment of degenerative disease of the lumbar spine. PMID:25610845

  7. Image denoising by a direct variational minimization

    Directory of Open Access Journals (Sweden)

    Pilipović Stevan

    2011-01-01

    Full Text Available Abstract In this article we introduce a novel method for the image de-noising which combines a mathematically well-posdenes of the variational modeling with the efficiency of a patch-based approach in the field of image processing. It based on a direct minimization of an energy functional containing a minimal surface regularizer that uses fractional gradient. The minimization is obtained on every predefined patch of the image, independently. By doing so, we avoid the use of an artificial time PDE model with its inherent problems of finding optimal stopping time, as well as the optimal time step. Moreover, we control the level of image smoothing on each patch (and thus on the whole image by adapting the Lagrange multiplier using the information on the level of discontinuities on a particular patch, which we obtain by pre-processing. In order to reduce the average number of vectors in the approximation generator and still to obtain the minimal degradation, we combine a Ritz variational method for the actual minimization on a patch, and a complementary fractional variational principle. Thus, the proposed method becomes computationally feasible and applicable for practical purposes. We confirm our claims with experimental results, by comparing the proposed method with a couple of PDE-based methods, where we get significantly better denoising results specially on the oscillatory regions.

  8. Blackfolds, plane waves and minimal surfaces

    Science.gov (United States)

    Armas, Jay; Blau, Matthias

    2015-07-01

    Minimal surfaces in Euclidean space provide examples of possible non-compact horizon geometries and topologies in asymptotically flat space-time. On the other hand, the existence of limiting surfaces in the space-time provides a simple mechanism for making these configurations compact. Limiting surfaces appear naturally in a given space-time by making minimal surfaces rotate but they are also inherent to plane wave or de Sitter space-times in which case minimal surfaces can be static and compact. We use the blackfold approach in order to scan for possible black hole horizon geometries and topologies in asymptotically flat, plane wave and de Sitter space-times. In the process we uncover several new configurations, such as black helicoids and catenoids, some of which have an asymptotically flat counterpart. In particular, we find that the ultraspinning regime of singly-spinning Myers-Perry black holes, described in terms of the simplest minimal surface (the plane), can be obtained as a limit of a black helicoid, suggesting that these two families of black holes are connected. We also show that minimal surfaces embedded in spheres rather than Euclidean space can be used to construct static compact horizons in asymptotically de Sitter space-times.

  9. Multiple objectives application approach to waste minimization

    Institute of Scientific and Technical Information of China (English)

    张清宇

    2002-01-01

    Besides economics and controllability, waste minimization has now become an obje ctive in designing chemical processes, and usually leads to high costs of invest ment and operation. An attempt was made to minimize waste discharged from chemic al reaction processes during the design and modification process while the opera tion conditions were also optimized to meet the requirements of technology and e conomics. Multiobjectives decision nonlinear programming (NLP) was employed to o ptimize the operation conditions of a chemical reaction process and reduce waste . A modeling language package-SPEEDUP was used to simulate the process. This p aper presents a case study of the benzene production process. The flowsheet factors affecting the economics and waste generation were examined. Constraints were imposed to reduce the number of objectives and carry out optimal calculations e asily. After comparisons of all possible solutions, best-compromise approach wa s applied to meet technological requirements and minimize waste.

  10. Minimal perceptrons for memorizing complex patterns

    Science.gov (United States)

    Pastor, Marissa; Song, Juyong; Hoang, Danh-Tai; Jo, Junghyo

    2016-11-01

    Feedforward neural networks have been investigated to understand learning and memory, as well as applied to numerous practical problems in pattern classification. It is a rule of thumb that more complex tasks require larger networks. However, the design of optimal network architectures for specific tasks is still an unsolved fundamental problem. In this study, we consider three-layered neural networks for memorizing binary patterns. We developed a new complexity measure of binary patterns, and estimated the minimal network size for memorizing them as a function of their complexity. We formulated the minimal network size for regular, random, and complex patterns. In particular, the minimal size for complex patterns, which are neither ordered nor disordered, was predicted by measuring their Hamming distances from known ordered patterns. Our predictions agree with simulations based on the back-propagation algorithm.

  11. Responsiveness and minimal clinically important change

    DEFF Research Database (Denmark)

    Christiansen, David Høyrup; Frost, Poul; Falla, Deborah

    2015-01-01

    Study Design A prospective cohort study nested in a randomized controlled trial. Objectives To determine and compare responsiveness and minimal clinically important change of the modified Constant score (CS) and the Oxford Shoulder Score (OSS). Background The OSS and the CS are commonly used...... to assess shoulder outcomes. However, few studies have evaluated the measurement properties of the OSS and CS in terms of responsiveness and minimal clinically important change. Methods The study included 126 patients who reported having difficulty returning to usual activities 8 to 12 weeks after...... were observed for the CS and the OSS. Minimal clinically important change ROC values were 6 points for the OSS and 11 points for the CS, with upper 95% cutoff limits of 12 and 22 points, respectively. Conclusion The CS and the OSS were both suitable for assessing improvement after decompression surgery....

  12. Best practices for minimally invasive procedures.

    Science.gov (United States)

    Ulmer, Brenda C

    2010-05-01

    Techniques and instrumentation for minimally invasive surgical procedures originated in gynecologic surgery, but the benefits of surgery with small incisions or no incisions at all have prompted the expansion of these techniques into numerous specialties. Technologies such as robotic assistance, single-incision laparoscopic surgery, natural orifice transluminal endoscopic surgery, and video-assisted thoracoscopic surgery have led to the continued expansion of minimally invasive surgery into new specialties. With this expansion, perioperative nurses and other members of the surgical team are required to continue to learn about new technology and instrumentation, as well as the techniques and challenges involved in using new technology, to help ensure the safety of their patients. This article explores the development of minimally invasive procedures and offers suggestions for increasing patient safety.

  13. Multiple objectives application approach to waste minimization

    Institute of Scientific and Technical Information of China (English)

    张清宇

    2002-01-01

    Besides econormics and controllability, waste minimization has now become an objective in designing chemical processes,and usually leads to high costs of investment and operation.An attempt was mede to minimize waste discharged from chemical reaction processes during the design and modification process while the operation conditions were also optimized to meet the requirements of technology and economics.Multiob-jectives decision nonlinear programming(NLP) was emplyed optimize the operation conditions of a chemical reaction process and reduce waste. A modeling package-SPEEDUP was used to simulate the process.This paper presents a case study of the benzenc production process.The flowsheer factors affecting the economics and waste generation were examined.Constraints were imposed to reduce the number of objectives and carry out optimal calculations easily.After comparisons of all possiblle solutions,best-compromise approach was applied to meet technological requirements and minimize waste.

  14. Minimal flavour violation and anomalous top decays

    Energy Technology Data Exchange (ETDEWEB)

    Faller, Sven; Mannel, Thomas [Theoretische Physik 1, Department Physik, Universitaet Siegen, D-57068 Siegen (Germany); Gadatsch, Stefan [Nikhef, National Institute for Subatomatic Physics, P.O. Box 41882, 1009 Amsterdam (Netherlands)

    2013-07-01

    Any experimental evidence of anomalous top-quark couplings will open a window to study physics beyond the standard model (SM). However, all current flavour data indicate that nature is close to ''minimal flavour violation'', i.e. the pattern of flavour violation is given by the CKM matrix, including the hierarchy of parameters. In this talk we present results of the conceptual test of minimal flavour violation for the anomalous charged as well as flavour changing top-quark couplings. Our analysis is embedded in two-Higgs doublet model of type II (2HDM-II). Including renormalization effects, we calculate the top decay rates taking into account anomalous couplings constrained by minimal flavour violation.

  15. Minimal Length Scale Scenarios for Quantum Gravity

    Directory of Open Access Journals (Sweden)

    Sabine Hossenfelder

    2013-01-01

    Full Text Available We review the question of whether the fundamental laws of nature limit our ability to probe arbitrarily short distances. First, we examine what insights can be gained from thought experiments for probes of shortest distances, and summarize what can be learned from different approaches to a theory of quantum gravity. Then we discuss some models that have been developed to implement a minimal length scale in quantum mechanics and quantum field theory. These models have entered the literature as the generalized uncertainty principle or the modified dispersion relation, and have allowed the study of the effects of a minimal length scale in quantum mechanics, quantum electrodynamics, thermodynamics, black-hole physics and cosmology. Finally, we touch upon the question of ways to circumvent the manifestation of a minimal length scale in short-distance physics.

  16. Minimal Length Scale Scenarios for Quantum Gravity.

    Science.gov (United States)

    Hossenfelder, Sabine

    2013-01-01

    We review the question of whether the fundamental laws of nature limit our ability to probe arbitrarily short distances. First, we examine what insights can be gained from thought experiments for probes of shortest distances, and summarize what can be learned from different approaches to a theory of quantum gravity. Then we discuss some models that have been developed to implement a minimal length scale in quantum mechanics and quantum field theory. These models have entered the literature as the generalized uncertainty principle or the modified dispersion relation, and have allowed the study of the effects of a minimal length scale in quantum mechanics, quantum electrodynamics, thermodynamics, black-hole physics and cosmology. Finally, we touch upon the question of ways to circumvent the manifestation of a minimal length scale in short-distance physics.

  17. Cogging Torque Minimization in Transverse Flux Machines

    Energy Technology Data Exchange (ETDEWEB)

    Husain, Tausif; Hasan, Iftekhar; Sozer, Yilmaz; Husain, Iqbal; Muljadi, Eduard

    2017-02-16

    This paper presents the design considerations in cogging torque minimization in two types of transverse flux machines. The machines have a double stator-single rotor configuration with flux concentrating ferrite magnets. One of the machines has pole windings across each leg of an E-Core stator. Another machine has quasi-U-shaped stator cores and a ring winding. The flux in the stator back iron is transverse in both machines. Different methods of cogging torque minimization are investigated. Key methods of cogging torque minimization are identified and used as design variables for optimization using a design of experiments (DOE) based on the Taguchi method. A three-level DOE is performed to reach an optimum solution with minimum simulations. Finite element analysis is used to study the different effects. Two prototypes are being fabricated for experimental verification.

  18. Derivation of $m_A \\simeq M_Z$ and $\\tan \\beta > \\sqrt 3$ in the Minimal Supersymmetric Standard Model

    CERN Document Server

    Ma, E

    1994-01-01

    In the minimal supersymmetric standard model, the Higgs sector has two unknown parameters, usually taken to be $\\tan \\beta \\equiv v_2/v_1$ and $m_A$, the mass of its one physical pseudoscalar particle. By minimizing the minimum of the Higgs potential along a certain direction in parameter space, it is shown that $m_A = M_Z$ + radiative correction, and if one further plausible assumption is made, $\\tan \\beta > \\sqrt 3$.

  19. Radiative Cooling: Principles, Progress, and Potentials.

    Science.gov (United States)

    Hossain, Md Muntasir; Gu, Min

    2016-07-01

    The recent progress on radiative cooling reveals its potential for applications in highly efficient passive cooling. This approach utilizes the maximized emission of infrared thermal radiation through the atmospheric window for releasing heat and minimized absorption of incoming atmospheric radiation. These simultaneous processes can lead to a device temperature substantially below the ambient temperature. Although the application of radiative cooling for nighttime cooling was demonstrated a few decades ago, significant cooling under direct sunlight has been achieved only recently, indicating its potential as a practical passive cooler during the day. In this article, the basic principles of radiative cooling and its performance characteristics for nonradiative contributions, solar radiation, and atmospheric conditions are discussed. The recent advancements over the traditional approaches and their material and structural characteristics are outlined. The key characteristics of the thermal radiators and solar reflectors of the current state-of-the-art radiative coolers are evaluated and their benchmarks are remarked for the peak cooling ability. The scopes for further improvements on radiative cooling efficiency for optimized device characteristics are also theoretically estimated.

  20. Minimally invasive surgical techniques in periodontal regeneration.

    Science.gov (United States)

    Cortellini, Pierpaolo

    2012-09-01

    A review of the current scientific literature was undertaken to evaluate the efficacy of minimally invasive periodontal regenerative surgery in the treatment of periodontal defects. The impact on clinical outcomes, surgical chair-time, side effects and patient morbidity were evaluated. An electronic search of PUBMED database from January 1987 to December 2011 was undertaken on dental journals using the key-word "minimally invasive surgery". Cohort studies, retrospective studies and randomized controlled clinical trials referring to treatment of periodontal defects with at least 6 months of follow-up were selected. Quality assessment of the selected studies was done through the Strength of Recommendation Taxonomy Grading (SORT) System. Ten studies (1 retrospective, 5 cohorts and 4 RCTs) were included. All the studies consistently support the efficacy of minimally invasive surgery in the treatment of periodontal defects in terms of clinical attachment level gain, probing pocket depth reduction and minimal gingival recession. Six studies reporting on side effects and patient morbidity consistently indicate very low levels of pain and discomfort during and after surgery resulting in a reduced intake of pain-killers and very limited interference with daily activities in the post-operative period. Minimally invasive surgery might be considered a true reality in the field of periodontal regeneration. The observed clinical improvements are consistently associated with very limited morbidity to the patient during the surgical procedure as well as in the post-operative period. Minimally invasive surgery, however, cannot be applied at all cases. A stepwise decisional algorithm should support clinicians in choosing the treatment approach.

  1. Review of Minimal Flavor Constraints for Technicolor

    DEFF Research Database (Denmark)

    S. Fukano, Hidenori; Sannino, Francesco

    2010-01-01

    We analyze the constraints on the the vacuum polarization of the standard model gauge bosons from a minimal set of flavor observables valid for a general class of models of dynamical electroweak symmetry breaking. We will show that the constraints have a strong impact on the self-coupling and mas......We analyze the constraints on the the vacuum polarization of the standard model gauge bosons from a minimal set of flavor observables valid for a general class of models of dynamical electroweak symmetry breaking. We will show that the constraints have a strong impact on the self...

  2. A New Minimal Rough Set Axiom Group

    Institute of Scientific and Technical Information of China (English)

    DAI Jian-hua

    2004-01-01

    Rough set axiomatization is one aspect of rough set study, and the purpose is to characterize rough set theory using independable and minimal axiom groups. Thus, rough set theory can be studied by logic and axiom system methods. To characterize rough set theory, an axiom group named H consisting of 4 axioms, is proposed. That validity of the axiom group in characterizing rough set theory is reasonable, is proved. Simultaneously, the minimization of the axiom group, which requires that each axiom is an inequality and each is independent, is proved. The axiom group is helpful for researching rough set theory by logic and axiom system methods.

  3. On Time with Minimal Expected Cost!

    DEFF Research Database (Denmark)

    David, Alexandre; Jensen, Peter Gjøl; Larsen, Kim Guldstrand

    2014-01-01

    ) timed game essentially defines an infinite-state Markov (reward) decision proces. In this setting the objective is classically to find a strategy that will minimize the expected reachability cost, but with no guarantees on worst-case behaviour. In this paper, we provide efficient methods for computing...... reachability strategies that will both ensure worst case time-bounds as well as provide (near-) minimal expected cost. Our method extends the synthesis algorithms of the synthesis tool Uppaal-Tiga with suitable adapted reinforcement learning techniques, that exhibits several orders of magnitude improvements w...

  4. Minimally invasive treatments for perforator vein insufficiency.

    Science.gov (United States)

    Kuyumcu, Gokhan; Salazar, Gloria Maria; Prabhakar, Anand M; Ganguli, Suvranu

    2016-12-01

    Incompetent superficial veins are the most common cause of lower extremity superficial venous reflux and varicose veins; however, incompetent or insufficient perforator veins are the most common cause of recurrent varicose veins after treatment, often unrecognized. Perforator vein insufficiency can result in pain, skin changes, and skin ulcers, and often merit intervention. Minimally invasive treatments have replaced traditional surgical treatments for incompetent perforator veins. Current minimally invasive treatment options include ultrasound guided sclerotherapy (USGS) and endovascular thermal ablation (EVTA) with either laser or radiofrequency energy sources. Advantages and disadvantages of each modality and knowledge on these treatments are required to adequately address perforator venous disease.

  5. Minimal String Theory and the Douglas Equation

    Science.gov (United States)

    Belavin, A. A.; Belavin, V. A.

    We use the connection between the Frobenius manifold and the Douglas string equation to further investigate Minimal Liouville gravity. We search for a solution of the Douglas string equation and simultaneously a proper transformation from the KdV to the Liouville frame which ensures the fulfilment of the conformal and fusion selection rules. We find that the desired solution of the string equation has an explicit and simple form in the flat coordinates on the Frobenius manifold in the general case of (p,q) Minimal Liouville gravity.

  6. The concept of minimally invasive dentistry.

    Science.gov (United States)

    Ericson, Dan

    2007-01-01

    This paper reviews Minimally Invasive Dentistry (MID) from a day-to-day dentistry perspective, focusing mostly on cariology and restorative dentistry, even though it embraces many aspects of dentistry. The concept of MID supports a systematic respect for the original tissue, including diagnosis, risk assessment, preventive treatment, and minimal tissue removal upon restoration. The motivation for MID emerges from the fact that fillings are not permanent and that the main reasons for failure are secondary caries and filling fracture. To address these flaws, there is a need for economical re-routing so that practices can survive on maintaining dental health and not only by operative procedures.

  7. Minimally invasive restorative dentistry: a biomimetic approach.

    Science.gov (United States)

    Malterud, Mark I

    2006-08-01

    When providing dental treatment for a given patient, the practitioner should use a minimally invasive technique that conserves sound tooth structure as a clinical imperative. Biomimetics is a tenet that guides the author's practice and is generally described as the mimicking of natural life. This can be accomplished in many cases using contemporary composite resins and adhesive dental procedures. Both provide clinical benefits and support the biomimetic philosophy for treatment. This article illustrates a minimally invasive approach for the restoration of carious cervical defects created by poor hygiene exacerbated by the presence of orthodontic brackets.

  8. Minimal Superstrings and Loop Gas Models

    CERN Document Server

    Gaiotto, D; Takayanagi, T; Gaiotto, Davide; Rastelli, Leonardo; Takayanagi, Tadashi

    2005-01-01

    We reformulate the matrix models of minimal superstrings as loop gas models on random surfaces. In the continuum limit, this leads to the identification of minimal superstrings with certain bosonic string theories, to all orders in the genus expansion. RR vertex operators arise as operators in a Z_2 twisted sector of the matter CFT. We show how the loop gas model implements the sum over spin structures expected from the continuum RNS formulation. Open string boundary conditions are also more transparent in this language.

  9. Linear embedding of free energy minimization

    CERN Document Server

    Moussa, Jonathan E

    2016-01-01

    Exact free energy minimization is a convex optimization problem that is usually approximated with stochastic sampling methods. Deterministic approximations have been less successful because many desirable properties have been difficult to attain. Such properties include the preservation of convexity, lower bounds on free energy, and applicability to systems without subsystem structure. We satisfy all of these properties by embedding free energy minimization into a linear program over energy-resolved expectation values. Numerical results on small systems are encouraging, but a lack of size consistency necessitates further development for large systems.

  10. Linearized non-minimal higher curvature supergravity

    Directory of Open Access Journals (Sweden)

    Fotis Farakos

    2015-05-01

    Full Text Available In the framework of linearized non-minimal supergravity (20/20, we present the embedding of the R+R2 model and we analyze its field spectrum. As usual, the auxiliary fields of the Einstein theory now become propagating, giving rise to additional degrees of freedom, which organize themselves into on-shell irreducible supermultiplets. By performing the analysis both in component and superspace formulations we identify the new supermultiplets. On top of the two massive chiral superfields reminiscent of the old-minimal supergravity embedding, the spectrum contains also a consistent physical, massive, vector supermultiplet and a tachyonic ghost, massive, vector supermultiplet.

  11. Linearized non-minimal higher curvature supergravity

    Science.gov (United States)

    Farakos, Fotis; Kehagias, Alex; Koutrolikos, Konstantinos

    2015-05-01

    In the framework of linearized non-minimal supergravity (20/20), we present the embedding of the R +R2 model and we analyze its field spectrum. As usual, the auxiliary fields of the Einstein theory now become propagating, giving rise to additional degrees of freedom, which organize themselves into on-shell irreducible supermultiplets. By performing the analysis both in component and superspace formulations we identify the new supermultiplets. On top of the two massive chiral superfields reminiscent of the old-minimal supergravity embedding, the spectrum contains also a consistent physical, massive, vector supermultiplet and a tachyonic ghost, massive, vector supermultiplet.

  12. Linearized Non-Minimal Higher Curvature Supergravity

    CERN Document Server

    Farakos, Fotis; Koutrolikos, Konstantinos

    2015-01-01

    In the framework of linearized non-minimal supergravity (20/20), we present the embedding of the $R + R^2$ model and we analyze its field spectrum. As usual, the auxiliary fields of the Einstein theory now become propagating, giving rise to additional degrees of freedom, which organize themselves into on-shell irreducible supermultiplets. By performing the analysis both in component and superspace formulations we identify the new supermultiplets. On top of the two massive chiral superfields reminiscent of the old-minimal supergravity embedding, the spectrum contains also a consistent physical, massive, vector supermultiplet and a tachyonic ghost, massive, vector supermultiplet.

  13. MINIMAL IMMERSIONS OF SPHERES INTO SPHERES

    Science.gov (United States)

    Do Carmo, Manfredo P.; Wallach, Nolan R.

    1969-01-01

    In this paper we announce a qualitative description of an important class of closed n-dimensional submanifolds of the m-dimensional sphere, namely, those which locally minimize the n-area in the same way that geodesics minimize the arc length and are themselves locally n-spheres of constant radius r; those r that may appear are called admissible. It is known that for n = 2 each admissible r determines a unique element of the above class. The main result here is that for each n ≥ 3 and each admissible r ≥ [unk]8 there exists a continuum of distinct such submanifolds. PMID:16591771

  14. Flexible Sensors for Minimally Invasive Medical Instruments

    NARCIS (Netherlands)

    Mimoun, B.A.Z.

    2013-01-01

    Being able to measure medical parameters directly inside the body in a minimally invasive way allows for a more accurate, faster, safer and cheaper diagnosis. A typical example can be found in the diagnosis of coronary artery diseases, where simultaneous measurement of intracoronary blood flow and p

  15. Mesonic spectroscopy of Minimal Walking Technicolor

    DEFF Research Database (Denmark)

    Del Debbio, Luigi; Lucini, Biagio; Patella, Agostino

    2010-01-01

    We investigate the structure and the novel emerging features of the mesonic non-singlet spectrum of the Minimal Walking Technicolor (MWT) theory. Precision measurements in the nonsinglet pseudoscalar and vector channels are compared to the expectations for an IR-conformal field theory and a QCD...

  16. MULTIOBJECTIVE PARALLEL GENETIC ALGORITHM FOR WASTE MINIMIZATION

    Science.gov (United States)

    In this research we have developed an efficient multiobjective parallel genetic algorithm (MOPGA) for waste minimization problems. This MOPGA integrates PGAPack (Levine, 1996) and NSGA-II (Deb, 2000) with novel modifications. PGAPack is a master-slave parallel implementation of a...

  17. Waste Minimization Program. Air Force Plant 6.

    Science.gov (United States)

    1986-02-01

    coolant’s life, it can cause the formation of gummy residues on machines and parts and cause corrosion of the machine and work tools. i 3-91e 0 _ b-4 LA...consists primarily of cans, applicators and rags contaminated with the - chrome- bearing hardened sealant. No opportunities to minimize this waste stream

  18. Maximally Minimal Preons in Four Dimensions

    CERN Document Server

    Grover, J; Sabra, W A; Grover, Jai; Gutowski, Jan B.; Sabra, Wafic A.

    2006-01-01

    Killing spinors of N=2, D=4 supergravity are examined using the spinorial geometry method, in which spinors are written as differential forms. Using this method, we show that there are no exactly 3/4 supersymmetric solutions of minimal N=2, D=4 gauged supergravity.

  19. Blackfolds, Plane Waves and Minimal Surfaces

    CERN Document Server

    Armas, Jay

    2015-01-01

    Minimal surfaces in Euclidean space provide examples of possible non-compact horizon geometries and topologies in asymptotically flat space-time. On the other hand, the existence of limiting surfaces in the space-time provides a simple mechanism for making these configurations compact. Limiting surfaces appear naturally in a given space-time by making minimal surfaces rotate but they are also inherent to plane wave or de Sitter space-times in which case minimal surfaces can be static and compact. We use the blackfold approach in order to scan for possible black hole horizon geometries and topologies in asymptotically flat, plane wave and de Sitter space-times. In the process we uncover several new configurations, such as black helicoids and catenoids, some of which have an asymptotically flat counterpart. In particular, we find that the ultraspinning regime of singly-spinning Myers-Perry black holes, described in terms of the simplest minimal surface (the plane), can be obtained as a limit of a black helicoid...

  20. Waste minimization in a petrochemical company

    Energy Technology Data Exchange (ETDEWEB)

    Anan, Marcelo [Oxiteno S.A., Industria e Comercio, Sao Paulo, SP (Brazil)

    1993-12-31

    A way to manage industrial effluents consists in reducing their generation or treating them when elimination or minimization is economically unachievable. This work aims to present the modifications adopted in a petrochemical plant to adequate and, or, reduce the generation of industrial effluent. 8 refs., 3 figs.

  1. Higher-Order Minimal Functional Graphs

    DEFF Research Database (Denmark)

    Jones, Neil D; Rosendahl, Mads

    1994-01-01

    We present a minimal function graph semantics for a higher-order functional language with applicative evaluation order. The semantics captures the intermediate calls performed during the evaluation of a program. This information may be used in abstract interpretation as a basis for proving...

  2. New Diagnostic Terminology for Minimal Brain Dysfunction.

    Science.gov (United States)

    Shaywitz, Bennett A.; And Others

    1979-01-01

    Minimal brain dysfunction has been redefined by the American Psychological Association as attention deficit disorder (ADD) and subdivided into categories with and without hyperactivity. The revised 'Diagnostic and Statistical Manual' (DSM III) is now undergoing field trials. Journal Availability: C. V. Mosby Company, 11830 Westline Industrial…

  3. Minimal Mimicry: Mere Effector Matching Induces Preference

    Science.gov (United States)

    Sparenberg, Peggy; Topolinski, Sascha; Springer, Anne; Prinz, Wolfgang

    2012-01-01

    Both mimicking and being mimicked induces preference for a target. The present experiments investigate the minimal sufficient conditions for this mimicry-preference link to occur. We argue that mere effector matching between one's own and the other person's movement is sufficient to induce preference, independent of which movement is actually…

  4. Minimal projections with respect to various norms

    CERN Document Server

    Aksoy, Asuman Guven

    2010-01-01

    We will show that a theorem of Rudin \\cite{wr1}, \\cite{wr}, permits us to determine minimal projections not only with respect to the operator norm but with respect to quasi-norms in operators ideals and numerical radius in many concrete cases.

  5. Minimally invasive surgery for Achilles tendon pathologies

    Directory of Open Access Journals (Sweden)

    Nicola Maffulli

    2010-07-01

    Full Text Available Nicola Maffulli1, Umile Giuseppe Longo2, Filippo Spiezia2, Vincenzo Denaro21Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, London, England; 2Department of Orthopedic and Trauma Surgery, Campus Bio-Medico University, Rome, ItalyAbstract: Minimally invasive trauma and orthopedic surgery is increasingly common, though technically demanding. Its use for pathologies of the Achilles tendon (AT hold the promise to allow faster recovery times, shorter hospital stays, and improved functional outcomes when compared to traditional open procedures, which can lead to difficulty with wound healing because of the tenuous blood supply and increased chance of wound breakdown and infection. We present the recent advances in the field of minimally invasive AT surgery for tendinopathy, acute ruptures, chronic tears, and chronic avulsions of the AT. In our hands, minimally invasive surgery has provided similar results to those obtained with open surgery, with decreased perioperative morbidity, decreased duration of hospital stay, and reduced costs. So far, the studies on minimally invasive orthopedic techniques are of moderate scientific quality with short follow-up periods. Multicenter studies with longer follow-up are needed to justify the long-term advantages of these techniques over traditional ones.Keywords: tendinopathy, rupture, percutanous repair, less invasive

  6. Minimal Function Graphs are not Instrumented

    DEFF Research Database (Denmark)

    Mycroft, Alan; Rosendahl, Mads

    1992-01-01

    The minimal function graph semantics of Jones and Mycroft is a standard denotational semantics modified to include only `reachable' parts of a program. We show that it may be expressed directly in terms of the standard semantics without the need for instrumentation at the expression level and, in...

  7. Minimizing convex functions by continuous descent methods

    Directory of Open Access Journals (Sweden)

    Sergiu Aizicovici

    2010-01-01

    Full Text Available We study continuous descent methods for minimizing convex functions, defined on general Banach spaces, which are associated with an appropriate complete metric space of vector fields. We show that there exists an everywhere dense open set in this space of vector fields such that each of its elements generates strongly convergent trajectories.

  8. Minimizing driver's irritation at a roadblock

    CERN Document Server

    Vleugels, C J J; Anthonissen, M J H; Seidman, T I

    2013-01-01

    Urban traffic is a logistic issue which can have many societal implications, especially when, due to a too high density of cars, the network of streets of a city becomes blocked, and consequently, pedestrians, bicycles, and cars start sharing the same traffic conditions potentially leading to high irritations (of people) and therefore to chaos. In this paper we focus our attention on a simple scenario: We model the driver's irritation induced by the presence of a roadblock. As a natural generalization, we extend the model for the two one-way crossroads traffic presented by M.E. Fouladvand and M. Nematollahi to that of a roadblock. Our discrete model defines and minimizes the total waiting time. The novelty lies in introducing the (total) driver's irritation and its minimization. Finally, we apply our model to a real-world situation: rush hour traffic in Hillegom, The Netherlands. We observe that minimizing the total waiting time and minimizing the total driver's irritation lead to different traffic light stra...

  9. Minimal requirements for rotation of bacterial flagella.

    OpenAIRE

    Ravid, S; Eisenbach, M

    1984-01-01

    An in vitro system of cell envelopes from Salmonella typhimurium with functional flagella was used to determine the minimal requirements for flagellar rotation. Rotation in the absence of cytoplasmic constituents could be driven either by respiration or by an artificially imposed chemical gradient of protons. No specific ionic requirements other than protons (or hydroxyls) were found for the motor function.

  10. An algorithm for reduct cardinality minimization

    KAUST Repository

    AbouEisha, Hassan M.

    2013-12-01

    This is devoted to the consideration of a new algorithm for reduct cardinality minimization. This algorithm transforms the initial table to a decision table of a special kind, simplify this table, and use a dynamic programming algorithm to finish the construction of an optimal reduct. Results of computer experiments with decision tables from UCI ML Repository are discussed. © 2013 IEEE.

  11. Positive Formulas in Intuitionistic and Minimal Logic

    NARCIS (Netherlands)

    de Jongh, D.; Zhao, Z.; Aher, M.; Hole, D.; Jeřábek, E.; Kupke, C.

    2015-01-01

    In this article we investigate the positive, i.e. ¬,⊥-free formulas of intuitionistic propositional and predicate logic, IPC and IQC, and minimal logic, MPC and MQC. For each formula φ of IQC we define the positive formula φ+ that represents the positive content of φ. The formulas φ and φ+ exhibit t

  12. Minimally inconsistent reasoning in Semantic Web

    Science.gov (United States)

    Zhang, Xiaowang

    2017-01-01

    Reasoning with inconsistencies is an important issue for Semantic Web as imperfect information is unavoidable in real applications. For this, different paraconsistent approaches, due to their capacity to draw as nontrivial conclusions by tolerating inconsistencies, have been proposed to reason with inconsistent description logic knowledge bases. However, existing paraconsistent approaches are often criticized for being too skeptical. To this end, this paper presents a non-monotonic paraconsistent version of description logic reasoning, called minimally inconsistent reasoning, where inconsistencies tolerated in the reasoning are minimized so that more reasonable conclusions can be inferred. Some desirable properties are studied, which shows that the new semantics inherits advantages of both non-monotonic reasoning and paraconsistent reasoning. A complete and sound tableau-based algorithm, called multi-valued tableaux, is developed to capture the minimally inconsistent reasoning. In fact, the tableaux algorithm is designed, as a framework for multi-valued DL, to allow for different underlying paraconsistent semantics, with the mere difference in the clash conditions. Finally, the complexity of minimally inconsistent description logic reasoning is shown on the same level as the (classical) description logic reasoning. PMID:28750030

  13. Construction and minimality of coordinated linear systems

    NARCIS (Netherlands)

    Kempker, P.L.; Ran, A.C.M.; Schuppen, J.H. van

    2014-01-01

    Coordinated linear systems are a particular class of hierarchical systems with a top-to-bottom information structure, consisting of a coordinator system and two or more subsystems. This paper deals with the construction and minimality of coordinated linear systems. Construction procedures are given

  14. Minimal Interventions in the Teaching of Mathematics

    Science.gov (United States)

    Foster, Colin

    2014-01-01

    This paper addresses ways in which mathematics pedagogy can benefit from insights gleaned from counselling. Person-centred counselling stresses the value of genuineness, warm empathetic listening and minimal intervention to support people in solving their own problems and developing increased autonomy. Such an approach contrasts starkly with the…

  15. Off-Critical Logarithmic Minimal Models

    CERN Document Server

    Pearce, Paul A

    2012-01-01

    We consider the integrable minimal models ${\\cal M}(m,m';t)$, corresponding to the $\\varphi_{1,3}$ perturbation off-criticality, in the {\\it logarithmic limit\\,} $m, m'\\to\\infty$, $m/m'\\to p/p'$ where $p, p'$ are coprime and the limit is taken through coprime values of $m,m'$. We view these off-critical minimal models ${\\cal M}(m,m';t)$ as the continuum scaling limit of the Forrester-Baxter Restricted Solid-On-Solid (RSOS) models on the square lattice. Applying Corner Transfer Matrices to the Forrester-Baxter RSOS models in Regime III, we argue that taking first the thermodynamic limit and second the {\\it logarithmic limit\\,} yields off-critical logarithmic minimal models ${\\cal LM}(p,p';t)$ corresponding to the $\\varphi_{1,3}$ perturbation of the critical logarithmic minimal models ${\\cal LM}(p,p')$. Specifically, in accord with the Kyoto correspondence principle, we show that the logarithmic limit of the one-dimensional configurational sums yields finitized quasi-rational characters of the Kac representatio...

  16. Non-minimally flavour violating dark matter

    CERN Document Server

    Blanke, Monika

    2015-01-01

    Flavour symmetries provide an appealing mechanism to stabilize the dark matter particle. I present a simple model of quark flavoured dark matter that goes beyond the framework of minimal flavour violation. I discuss the phenomenological implications for direct and indirect dark matter detection experiments, high energy collider searches as well as flavour violating precision data.

  17. Minimal Guidelines for Authors of Web Pages.

    Science.gov (United States)

    ADE Bulletin, 2002

    2002-01-01

    Presents guidelines that recommend the minimal reference information that should be provided on Web pages intended for use by students, teachers, and scholars in the modern languages. Suggests the inclusion of information about responsible parties, copyright declaration, privacy statements, and site information. Makes a note on Web page style. (SG)

  18. Minimal Flat Resolutions of Artinian Modules

    Institute of Scientific and Technical Information of China (English)

    Sh. Payrovi

    2005-01-01

    The purpose of this paper is to establish connection between the minimal flat resolutions of Artinian modules and the concept of cosequences in commutative algebra.The main result of this paper leads to a characterization of local Cohen-Macaulay rings in terms of vanishing property of the dual Bass numbers of certain Artinian modules.

  19. Kundt spacetimes minimally coupled to scalar field

    Energy Technology Data Exchange (ETDEWEB)

    Tahamtan, T. [Charles University, Institute of Theoretical Physics, Faculty of Mathematics and Physics, Prague 8 (Czech Republic); Astronomical Institute, Czech Academy of Sciences, Prague (Czech Republic); Svitek, O. [Charles University, Institute of Theoretical Physics, Faculty of Mathematics and Physics, Prague 8 (Czech Republic)

    2017-06-15

    We derive an exact solution belonging to the Kundt class of spacetimes both with and without a cosmological constant that are minimally coupled to a free massless scalar field. We show the algebraic type of these solutions and give interpretation of the results. Subsequently, we look for solutions additionally containing an electromagnetic field satisfying nonlinear field equations. (orig.)

  20. The Rings Characterized by Minimal Left Ideals

    Institute of Scientific and Technical Information of China (English)

    Jun Chao WEI

    2005-01-01

    We study these rings with every minimal left ideal being a projective, direct summand and a p-injective module, respectively. Some characterizations of these rings are given, and the relations among them are obtained. With these rings, we characterize semisimple rings. Finally, we introduce MC2 rings, and give some characterizations of MC2 rings.

  1. Leptogenesis in minimal predictive seesaw models

    CERN Document Server

    Björkeroth, Fredrik; Varzielas, Ivo de Medeiros; King, Stephen F

    2015-01-01

    We estimate the Baryon Asymmetry of the Universe (BAU) arising from leptogenesis within a class of minimal predictive seesaw models involving two right-handed neutrinos and simple Yukawa structures with one texture zero. The two right-handed neutrinos are dominantly responsible for the "atmospheric" and "solar" neutrino masses with Yukawa couplings to $(\

  2. Infrared dynamics of Minimal Walking Technicolor

    DEFF Research Database (Denmark)

    Del Debbio, Luigi; Lucini, Biagio; Patella, Agostino;

    2010-01-01

    We study the gauge sector of Minimal Walking Technicolor, which is an SU(2) gauge theory with nf=2 flavors of Wilson fermions in the adjoint representation. Numerical simulations are performed on lattices Nt x Ns^3, with Ns ranging from 8 to 16 and Nt=2Ns, at fixed \\beta=2.25, and varying the fer...

  3. Integral Radiator and Storage Tank

    Science.gov (United States)

    Burke, Kenneth A.; Miller, John R.; Jakupca, Ian; Sargi,Scott

    2007-01-01

    A simplified, lightweight system for dissipating heat of a regenerative fuel- cell system would include a heat pipe with its evaporator end placed at the heat source and its condenser end integrated into the wall of the regenerative fuel cell system gas-storage tanks. The tank walls act as heat-radiating surfaces for cooling the regenerative fuel cell system. The system was conceived for use in outer space, where radiation is the only physical mechanism available for transferring heat to the environment. The system could also be adapted for use on propellant tanks or other large-surface-area structures to convert them to space heat-radiating structures. Typically for a regenerative fuel cell system, the radiator is separate from the gas-storage tanks. By using each tank s surface as a heat-radiating surface, the need for a separate, potentially massive radiator structure is eliminated. In addition to the mass savings, overall volume is reduced because a more compact packaging scheme is possible. The underlying tank wall structure provides ample support for heat pipes that help to distribute the heat over the entire tank surface. The heat pipes are attached to the outer surface of each gas-storage tank by use of a high-thermal conductance, carbon-fiber composite-material wrap. Through proper choice of the composite layup, it is possible to exploit the high longitudinal conductivity of the carbon fibers (greater than the thermal conductivity of copper) to minimize the unevenness of the temperature distribution over the tank surface, thereby helping to maximize the overall heat-transfer efficiency. In a prototype of the system, the heat pipe and the composite wrap contribute an average mass of 340 g/sq m of radiator area. Lightweight space radiator panels have a mass of about 3,000 g/sq m of radiator area, so this technique saves almost 90 percent of the mass of separate radiator panels. In tests, the modified surface of the tank was found to have an emissivity of 0

  4. Tracker Teleparallel Dark Energy with Purely Non-minimal Coupling to Gravity

    CERN Document Server

    Gu, Je-An; Geng, Chao-Qiang

    2012-01-01

    We investigate the teleparallel dark energy model with purely non-minimal coupling and without potential. We find the analytic solutions of the scalar field in the radiation, matter, and scalar field (or dark energy) dominated eras, respectively. These solutions indicate the tracker behavior in the radiation and matter dominated eras, while the equation of state $w_{\\phi}$ of the teleparallel dark energy is determined by the non-minimal coupling constant $\\xi$ but insensitive to the initial condition. In the scalar field dominated era, $w_{\\phi}$ monotonically decreases and goes to negative infinity at some finite time when $H$ goes to positive infinity, resulting in a future singularity. We also present the possible evolution patterns and the data fittings in this model.

  5. Quantization of the minimal and non-minimal vector field in curved space

    CERN Document Server

    Toms, David J

    2015-01-01

    The local momentum space method is used to study the quantized massive vector field (the Proca field) with the possible addition of non-minimal terms. Heat kernel coefficients are calculated and used to evaluate the divergent part of the one-loop effective action. It is shown that the naive expression for the effective action that one would write down based on the minimal coupling case needs modification. We adopt a Faddeev-Jackiw method of quantization and consider the case of an ultrastatic spacetime for simplicity. The operator that arises for non-minimal coupling to the curvature is shown to be non-minimal in the sense of Barvinsky and Vilkovisky. It is shown that when a general non-minimal term is added to the theory the result is not renormalizable with the addition of a local Lagrangian counterterm.

  6. The space radiation environment

    Energy Technology Data Exchange (ETDEWEB)

    Robbins, D.E.

    1997-04-30

    There are three primary sources of space radiation: galactic cosmic rays (GCR), trapped belt radiation, and solar particle events (SPE). All are composed of ions, the nuclei of atoms. Their energies range from a few MeV u{sup -1} to over a GeV u{sup -1}. These ions can fragment when they interact with spacecraft materials and produce energetic neutrons and ions of lower atomic mass. Absorbed dose rates inside a typical spacecraft (like the Space Shuttle) in a low inclination (28.5 degrees) orbit range between 0.05 and 2 mGy d{sup -1} depending on the altitude and flight inclination (angle of orbit with the equator). The quality factor of radiation in orbit depends on the relative contributions of trapped belt radiation and GCR, and the dose rate varies both with orbital altitude and inclination. The corresponding equivalent dose rate ranges between 0.1 and 4 mSv d{sup -1}. In high inclination orbits, like that of the Mir Space Station and as is planned for the International Space Station, blood-forming organ (BFO) equivalent dose rates as high as 1.5 mSv d{sup -1}. Thus, on a 1 y mission, a crew member could obtain a total dose of 0.55 Sv. Maximum equivalent dose rates measured in high altitude passes through the South Atlantic Anomaly (SAA) were 10 mSv h{sup -1}. For an interplanetary space mission (e.g., to Mars) annual doses from GCR alone range between 150 mSv y{sup -1} at solar maximum and 580 mSv y{sup -1} at solar minimum. Large SPE, like the October 1989 series, are more apt to occur in the years around solar maximum. In free space, such an event could contribute another 300 mSv, assuming that a warning system and safe haven can be effectively used with operational procedures to minimize crew exposures. Thus, the total dose for a 3 y mission to Mars could exceed 2 Sv.

  7. Radiative seesaw and degenerate neutrinos

    CERN Document Server

    Bajc, B; Bajc, Borut; Senjanovic, Goran

    2005-01-01

    The radiative see-saw mechanism of Witten generates the right-handed neutrino masses in SO(10) with the spinorial 16_H Higgs field. We study here analytically the 2nd and 3rd generations for the minimal Yukawa structure containing 10_H and 120_H Higgs representations. In the approximation of small 2nd generation masses and gauge loop domination we find the following results : (1) b-tau unification, (2) natural coexistence between large theta_l and small theta_q, (3) degenerate neutrinos.

  8. Adaptive Radiation for Lung Cancer

    Science.gov (United States)

    Gomez, Daniel R.; Chang, Joe Y.

    2011-01-01

    The challenges of lung cancer radiotherapy are intra/inter-fraction tumor/organ anatomy/motion changes and the need to spare surrounding critical structures. Evolving radiotherapy technologies, such as four-dimensional (4D) image-based motion management, daily on-board imaging and adaptive radiotherapy based on volumetric images over the course of radiotherapy, have enabled us to deliver higher dose to target while minimizing normal tissue toxicities. The image-guided radiotherapy adapted to changes of motion and anatomy has made the radiotherapy more precise and allowed ablative dose delivered to the target using novel treatment approaches such as intensity-modulated radiation therapy, stereotactic body radiation therapy, and proton therapy in lung cancer, techniques used to be considered very sensitive to motion change. Future clinical trials using real time tracking and biological adaptive radiotherapy based on functional images are proposed. PMID:20814539

  9. 淋巴瘤化疗后行受侵区域PET-CT扫描评价疗效的可行性研究%Minimizing radiation dose with PET-CT limited to involved sites in the assessment of postchemotherapy lymphoma

    Institute of Scientific and Technical Information of China (English)

    梁颖; 吴宁; 耿建华; 方艳; 郑容; 张雯杰; 刘瑛; 张瀚; 李小萌

    2013-01-01

    Objective To assess PET-CT scanning limited to involved sites in postchemotherapy lymphoma and explore possible radiation dose reductions.Methods Fifty-three lymphoma patients with prechemotherapy and postchemotherapy whole-body PET-CT were analyzed retrospectively.The involved sites were determined on prechemotherapy PET-CT scanning.Whole-body PET-CT scanning and hypothetical PET-CT limited to involved sites were compared in assessing clinical response to chemotherapy.The potential reductions in effective dose and total acquisition time achieved with PET-CT scanning limited to involved sites were calculated.Results Whole-body PET-CT scanning revealed CR in 37 cases,PR in 13 cases and PD in 3 cases in postchemotherapy lymphoma patients,while PET-CT scanning limited to involved sites revealed CR in 37 cases,PR in 14 cases and PD in 2 cases.The mean effective dose was(15.0 ± 1.7)mSv for per patients of CR with whole-body PET-CT scanning,and was (12.0 ± 2.5)mSv for per patients of CR with PET-CT scanning limited in involved sites(Z=-5.307,P<0.05).The mean acquisition time was(19.5 ±2.6)s for per patients of CR with whole-body PET-CT scanning,and(11.3 ± 4.4)s for per patient of CR with PET-CT scanning limited in involved sites(Z=-5.324,P<0.05).Conclusions Response assessment with PET-CT scanning limited in involved sites has good agreement with whole-body PET-CT scanning in postchemotherapy lymphoma patients with CR.Lymphoma patients with CR may benefit from reduced radiation dose and total acquisition time.PET-CT scanning limited in involved sites is not advisable in patients with PR or PD for poor agreement with whole-body PET-CT scanning in response assessment.%目的 为降低辐射剂量,探讨淋巴瘤化疗后采用受侵区域PET-CT扫描评价疗效的可行性.方法 回顾性分析53例化疗前、后均行全身PET-CT扫描的淋巴瘤初诊患者.将化疗前PET-CT所示的淋巴瘤侵犯范围定义为受侵区域,化疗后假设采用受侵区

  10. Radiation pneumonitis

    Energy Technology Data Exchange (ETDEWEB)

    Amla, T.R.; Chakravarti, R.N.; Lal, K.

    1975-07-01

    Adult healthy rhesus monkeys were exposed to a course of roentgen irradiation over the chest and back to produce pulmonary changes simulating human radiation pneumonitis. Macroscopic and morphologic changes included dense adhesions, pleural thickening and increased consistency of the lungs. Microscopically the early reaction was characterized by dilatation of pulmonary vessels, microhaemorrhages, collapse of alveoli, permeation of the interstitial tissue with a fibrinous fluid and cells. In the late stage the fibrinous interstitial matrix was replaced by hyaline eosinophilic mass, fragmentation and dissolution of the elastic tissue and thickening of the alveolar walls. The cell population in the interstitial tissue showed decline and at places radiolytic effect. There was peribronchial and perivascular fibrosis and hyalinization and pulmonary arteries revealed marked degree of arteriosclerosis. The present study opens a new field for experimental research on the development of pulmonary hypertension as a post-irradiation complication.

  11. Radiation Insulation

    Science.gov (United States)

    1995-01-01

    The Apollo and subsequent spacecraft have had highly effective radiation barriers; made of aluminized polymer film, they bar or let in heat to maintain consistent temperatures inside. Tech 2000, formerly Quantum International Corporation used the NASA technology in its insulating materials, Super "Q" Radiant Barrier, for home, industry and mobile applications. The insulation combines industrial aluminum foil overlaid around a core of another material, usually propylene or mylar. The outer layer reflects up to 97 percent of heat; the central layer creates a thermal break in the structure and thus allows low radiant energy emission. The Quantum Cool Wall, used in cars and trucks, takes up little space while providing superior insulation, thus reducing spoilage and costs. The panels can also dampen sound and engine, exhaust and solar heat.

  12. Predictions for Radiation Shielding Materials

    Science.gov (United States)

    Kiefer, Richard L.

    2002-01-01

    increase radiation damage due to penetration properties and nuclear fragmentation. Protecting space-borne microelectronics from single event upsets (SEUs) by transmitted radiation will benefit system reliability and system design cost by using optimal shield materials. Long-term missions on the surface of the Moon or Mars will require the construction of habitats to protect humans during their stay. One approach to the construction is to make structural materials from lunar or Martian regolith using a polymeric material as a binder. The hydrogen-containing polymers are considerably more effective for radiation protection than the regolith, but the combination minimizes the amount of polymer to be transported. We have made composites of simulated lunar regolith with two different polymers, LaRC-SI, a high-performance polyimide thermoset, and polyethylene, a thermoplastic.

  13. Systemic mastocytosis associated with minimal change disease

    Directory of Open Access Journals (Sweden)

    Tony Amin

    2016-07-01

    Full Text Available Systemic Mastocytosis (SM has not previously been reported in association with minimal change disease (MCD. Mastocytosis is a rare myeloproliferative disease that is characterised by uncontrolled proliferation of aberrant mast cells. This can lead to a wide variety of symptoms and can present as either a cutaneous or a systemic disease. Systemic manifestations usually include bone marrow, intestine, liver and splenic infiltration of mast cells, with reports of renal manifestations being rare. This is a case report of a 70-year-old man who was known to have Systemic Mastocytosis and who presented with nephrotic range proteinuria. Renal biopsy diagnosed Minimal Change Disease with mast cell infiltration being an identified by C-kit staining. The patient was treated with steroids and is currently in remission of the proteinuria.

  14. The Minimal Supersymmetric Fat Higgs Model

    CERN Document Server

    Harnik, R; Larson, D T; Murayama, H; Harnik, Roni; Kribs, Graham D.; Larson, Daniel T.; Murayama, Hitoshi

    2003-01-01

    We present a calculable supersymmetric theory of a composite ``fat'' Higgs boson. Electroweak symmetry is broken dynamically through a new gauge interaction that becomes strong at an intermediate scale. The Higgs mass can easily be 200-450 GeV along with the superpartner masses, solving the supersymmetric little hierarchy problem. We explicitly verify that the model is consistent with precision electroweak data without fine-tuning. Gauge coupling unification can be maintained despite the inherently strong dynamics involved in electroweak symmetry breaking. Supersymmetrizing the Standard Model therefore does not imply a light Higgs mass, contrary to the lore in the literature. The Higgs sector of the minimal Fat Higgs model has a mass spectrum that is distinctly different from the Minimal Supersymmetric Standard Model.

  15. Measurable Maximal Energy and Minimal Time Interval

    CERN Document Server

    Dahab, Eiman Abou El

    2014-01-01

    The possibility of finding the measurable maximal energy and the minimal time interval is discussed in different quantum aspects. It is found that the linear generalized uncertainty principle (GUP) approach gives a non-physical result. Based on large scale Schwarzshild solution, the quadratic GUP approach is utilized. The calculations are performed at the shortest distance, at which the general relativity is assumed to be a good approximation for the quantum gravity and at larger distances, as well. It is found that both maximal energy and minimal time have the order of the Planck time. Then, the uncertainties in both quantities are accordingly bounded. Some physical insights are addressed. Also, the implications on the physics of early Universe and on quantized mass are outlined. The results are related to the existence of finite cosmological constant and minimum mass (mass quanta).

  16. Revisiting the minimal chaotic inflation model

    Energy Technology Data Exchange (ETDEWEB)

    Harigaya, Keisuke, E-mail: keisukeharigaya@berkeley.edu [ICRR, University of Tokyo, Kashiwa, Chiba 277-8582 (Japan); Ibe, Masahiro; Kawasaki, Masahiro [ICRR, University of Tokyo, Kashiwa, Chiba 277-8582 (Japan); Kavli IPMU (WPI), UTIAS, University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Yanagida, Tsutomu T. [Kavli IPMU (WPI), UTIAS, University of Tokyo, Kashiwa, Chiba 277-8583 (Japan)

    2016-05-10

    We point out that the prediction of the minimal chaotic inflation model is altered if a scalar field takes a large field value close to the Planck scale during inflation due to a negative Hubble induced mass. In particular, we show that the inflaton potential is effectively flattened at a large inflaton field value in the presence of such a scalar field. The scalar field may be identified with the standard model Higgs field or super partners of standard model fermions. With such Hubble-induced flattening, we find that the minimal chaotic inflation model, especially the model with a quadratic potential, is consistent with recent observations of the cosmic microwave background fluctuation without modifying the inflation model itself.

  17. Quadratic Interpolation Algorithm for Minimizing Tabulated Function

    Directory of Open Access Journals (Sweden)

    E. A. Youness

    2008-01-01

    Full Text Available Problem statement: The problem of finding the minimum value of objective function, when we know only some values of it, is needed in more practical fields. Quadratic interpolation algorithms are the famous tools deal with this kind of these problems. These algorithms interested with the polynomial space in which the objective function is approximated. Approach: In this study we approximated the objective function by a one dimensional quadratic polynomial. This approach saved the time and the effort to get the best point at which the objective is minimized. Results: The quadratic polynomial in each one of the steps of the proposed algorithm, accelerate the convergent to the best value of the objective function without taking into account all points of the interpolation set. Conclusion: Any n-dimensional problem of finding a minimal value of a function, given by some values, can be converted to one dimensional problem easier in deal.

  18. Minimally Disruptive Medicine for Patients with Diabetes.

    Science.gov (United States)

    Serrano, Valentina; Spencer-Bonilla, Gabriela; Boehmer, Kasey R; Montori, Victor M

    2017-09-23

    Patients with diabetes must deal with the burden of symptoms and complications (burden of illness). Simultaneously, diabetes care demands practical and emotional work from patients and their families, work to access and use healthcare and to enact self-care (burden of treatment). Patient work must compete with the demands of family, job, and community life. Overwhelmed patients may not have the capacity to access care or enact self-care and will thus experience suboptimal diabetes outcomes. Minimally disruptive medicine (MDM) is a patient-centered approach to healthcare that prioritizes patients' goals for life and health while minimizing the healthcare disruption on patients' lives. In patients with diabetes, particularly in those with complex lives and multimorbidity, MDM coordinates healthcare and community responses to improve outcomes, reduce treatment burden, and enable patients to pursue their life's hopes and dreams.

  19. Facets of the balanced minimal evolution polytope.

    Science.gov (United States)

    Forcey, Stefan; Keefe, Logan; Sands, William

    2016-08-01

    The balanced minimal evolution (BME) method of creating phylogenetic trees can be formulated as a linear programming problem, minimizing an inner product over the vertices of the BME polytope. In this paper we undertake the project of describing the facets of this polytope. We classify and identify the combinatorial structure and geometry (facet inequalities) of all the facets in dimensions up to five, and classify even more facets in all dimensions. A full set of facet inequalities would allow a full implementation of the simplex method for finding the BME tree-although there are reasons to think this an unreachable goal. However, our results provide the crucial first steps for a more likely-to-be-successful program: finding efficient relaxations of the BME polytope.

  20. Neurocontroller analysis via evolutionary network minimization.

    Science.gov (United States)

    Ganon, Zohar; Keinan, Alon; Ruppin, Eytan

    2006-01-01

    This study presents a new evolutionary network minimization (ENM) algorithm. Neurocontroller minimization is beneficial for finding small parsimonious networks that permit a better understanding of their workings. The ENM algorithm is specifically geared to an evolutionary agents setup, as it does not require any explicit supervised training error, and is very easily incorporated in current evolutionary algorithms. ENM is based on a standard genetic algorithm with an additional step during reproduction in which synaptic connections are irreversibly eliminated. It receives as input a successfully evolved neurocontroller and aims to output a pruned neurocontroller, while maintaining the original fitness level. The small neurocontrollers produced by ENM provide upper bounds on the neurocontroller size needed to perform a given task successfully, and can provide for more effcient hardware implementations.

  1. Activity recognition from minimal distinguishing subsequence mining

    Science.gov (United States)

    Iqbal, Mohammad; Pao, Hsing-Kuo

    2017-08-01

    Human activity recognition is one of the most important research topics in the era of Internet of Things. To separate different activities given sensory data, we utilize a Minimal Distinguishing Subsequence (MDS) mining approach to efficiently find distinguishing patterns among different activities. We first transform the sensory data into a series of sensor triggering events and operate the MDS mining procedure afterwards. The gap constraints are also considered in the MDS mining. Given the multi-class nature of most activity recognition tasks, we modify the MDS mining approach from a binary case to a multi-class one to fit the need for multiple activity recognition. We also study how to select the best parameter set including the minimal and the maximal support thresholds in finding the MDSs for effective activity recognition. Overall, the prediction accuracy is 86.59% on the van Kasteren dataset which consists of four different activities for recognition.

  2. Absorbing angles, Steiner minimal trees, and antipodality

    CERN Document Server

    Martini, Horst; de Wet, P Oloff; 10.1007/s10957-009-9552-1

    2011-01-01

    We give a new proof that a star $\\{op_i:i=1,...,k\\}$ in a normed plane is a Steiner minimal tree of its vertices $\\{o,p_1,...,p_k\\}$ if and only if all angles formed by the edges at o are absorbing [Swanepoel, Networks \\textbf{36} (2000), 104--113]. The proof is more conceptual and simpler than the original one. We also find a new sufficient condition for higher-dimensional normed spaces to share this characterization. In particular, a star $\\{op_i: i=1,...,k\\}$ in any CL-space is a Steiner minimal tree of its vertices $\\{o,p_1,...,p_k\\}$ if and only if all angles are absorbing, which in turn holds if and only if all distances between the normalizations $\\frac{1}{\\|p_i\\|}p_i$ equal 2. CL-spaces include the mixed $\\ell_1$ and $\\ell_\\infty$ sum of finitely many copies of $R^1$.

  3. The method of minimal normal forms

    Energy Technology Data Exchange (ETDEWEB)

    Mane, S.R.; Weng, W.T.

    1992-12-31

    Normal form methods for solving nonlinear differential equations are reviewed and the comparative merits of three methods are evaluated. The concept of the minimal normal form is explained and is shown to be superior to other choices. The method is then extended to apply to the evaluation of discrete maps of an accelerator or storage ring. Such an extension, as suggested in this paper, is more suited for accelerator-based applications than a formulation utilizing continuous differential equations. A computer code has been generated to systematically implement various normal form formulations for maps in two-dimensional phase space. Specific examples of quadratic and cubic nonlinear fields were used and solved by the method developed. The minimal normal form method shown here gives good results using relatively low order expansions.

  4. The method of minimal normal forms

    Energy Technology Data Exchange (ETDEWEB)

    Mane, S.R.; Weng, W.T.

    1992-01-01

    Normal form methods for solving nonlinear differential equations are reviewed and the comparative merits of three methods are evaluated. The concept of the minimal normal form is explained and is shown to be superior to other choices. The method is then extended to apply to the evaluation of discrete maps of an accelerator or storage ring. Such an extension, as suggested in this paper, is more suited for accelerator-based applications than a formulation utilizing continuous differential equations. A computer code has been generated to systematically implement various normal form formulations for maps in two-dimensional phase space. Specific examples of quadratic and cubic nonlinear fields were used and solved by the method developed. The minimal normal form method shown here gives good results using relatively low order expansions.

  5. [Bilateral dependency and the minimal group paradigm].

    Science.gov (United States)

    Jin, N; Yamagishi, T; Kiyonari, T

    1996-06-01

    Two experiments examined the effect of illusion of control on in-group favoritism found in the minimal group situation (Tajfel, Billig, Bundy, & Flament, 1971). In bilateral dependency condition, each member made allocation decisions for in-group as well as out-group participants. It was exactly the same situation used in the original studies under the minimal group paradigm, and the subjects knew that their reward allocation too depended on others' decisions. In contrast, in unilateral dependency condition, the subjects made allocation decisions knowing that theirs were not dependent on others' decisions. In Experiment 1, an in-group bias in reward distribution was found in the bilateral dependency condition, but not in the unilateral condition. In Experiment 2, it was found that only those who felt illusion of control exhibited such an in-group bias. Results of the experiments therefore confirmed that illusion of control explained in-group favoritism, as Karp, Jin, Yamagishi, and Shinotsuka (1993) originally hypothesized.

  6. Discrete Curvatures and Discrete Minimal Surfaces

    KAUST Repository

    Sun, Xiang

    2012-06-01

    This thesis presents an overview of some approaches to compute Gaussian and mean curvature on discrete surfaces and discusses discrete minimal surfaces. The variety of applications of differential geometry in visualization and shape design leads to great interest in studying discrete surfaces. With the rich smooth surface theory in hand, one would hope that this elegant theory can still be applied to the discrete counter part. Such a generalization, however, is not always successful. While discrete surfaces have the advantage of being finite dimensional, thus easier to treat, their geometric properties such as curvatures are not well defined in the classical sense. Furthermore, the powerful calculus tool can hardly be applied. The methods in this thesis, including angular defect formula, cotangent formula, parallel meshes, relative geometry etc. are approaches based on offset meshes or generalized offset meshes. As an important application, we discuss discrete minimal surfaces and discrete Koenigs meshes.

  7. [Invasive and minimally invasive hemodynamic monitoring].

    Science.gov (United States)

    Hansen, Matthias

    2016-10-01

    Advanced hemodynamic monitoring is necessary for adequate management of high-risk patients or patients with derangement of circulation. Studies demonstrate a benefit of early goal directed therapy in unstable cardiopulmonary situations. In these days we have different possibilities of minimally invasive or invasive hemodynamic monitoring. Minimally invasive measurements like pulse conture analysis or pulse wave analysis being less accurate under some circumstances, however only an artery catheter is needed for cardiac output monitoring. Pulmonary artery, transpulmonary thermodilution and lithium dilution technology have acceptable accuracy in cardiac output measurement. For therapy of unstable circulation there are additionally parameters to obtain. The pulmonary artery catheter is the device with the largest rate of complications, used by a trained crew and with a correct indication, his use is unchained justified.

  8. Autonomous Preservation Tools in Minimal Effort Ingest

    DEFF Research Database (Denmark)

    Jurik, Bolette Ammitzbøll; Blekinge, Asger Askov; Andersen, Thorbjørn Ravn

    2016-01-01

    This poster presents the concept of Autonomous Preservation Tools, as developed by the State and University Library, Denmark. The work expands the idea of Minimal Effort Ingest, where most preservation actions such as Quality Assurance and enrichment of the digital objects are performed after con...... content is ingested for preservation, rather than before. We present our Newspaper Digitisation Project as a case-study of real-world implementations of Autonomous Preservation Tools.......This poster presents the concept of Autonomous Preservation Tools, as developed by the State and University Library, Denmark. The work expands the idea of Minimal Effort Ingest, where most preservation actions such as Quality Assurance and enrichment of the digital objects are performed after...

  9. Intuitive Minimal Abduction in Sequent Calculi

    Institute of Scientific and Technical Information of China (English)

    伊波; 陶先平; 等

    1998-01-01

    Sme computational issues on abduction are discussed in a framework of the first order sequent calculus.Starting from revising the meaning of “good” abduction ,a new criterion of abduction called intuitive-minimal abduction(IMA)is introduced.An IMA is an abuctive formula equivalent to the minimal abductive formula under the theory part of a sequent and literally as simple as possible.Abduction algorithms are presented on the basis of a complete natural reduction system.An abductive formula,obtained by the algorithms presented in this paper,is an IMA if the reduction tree,from which the abduction is performed,is fully expanded.Instead of using Skolem functions,a term-ordering is used to indicate dependency between terms.

  10. Qualifying and quantifying minimal hepatic encephalopathy

    DEFF Research Database (Denmark)

    Morgan, Marsha Y; Amodio, Piero; Cook, Nicola A

    2016-01-01

    . There is no gold standard for the diagnosis of this syndrome. As these patients have, by definition, no recognizable clinical features of brain dysfunction, the primary prerequisite for the diagnosis is careful exclusion of clinical symptoms and signs. A large number of psychometric tests/test systems have been...... analytical techniques may provide better diagnostic information while the advent of portable wireless headsets may facilitate more widespread use. A large number of other diagnostic tools have been validated for the diagnosis of minimal hepatic encephalopathy including Critical Flicker Frequency......, the Inhibitory Control Test, the Stroop test, the Scan package and the Continuous Reaction Time; each has its pros and cons; strengths and weaknesses; protagonists and detractors. Recent AASLD/EASL Practice Guidelines suggest that the diagnosis of minimal hepatic encephalopathy should be based on the PHES test...

  11. Minimization of Salmonella contamination on raw poultry.

    Science.gov (United States)

    Cox, N A; Cason, J A; Richardson, L J

    2011-01-01

    Many reviews have discussed Salmonella in poultry and suggested best practices to minimize this organism on raw poultry meat. Despite years of research and conscientious control efforts by industry and regulatory agencies, human salmonellosis rates have declined only modestly and Salmonella is still found on raw poultry. Expert committees have repeatedly emphasized the importance of controlling risk, but information about Salmonella in poultry is often limited to prevalence, with inadequate information about testing methods or strains of Salmonella that are detected by these methods and no information about any impact on the degree of risk. This review examines some assumptions behind the discussion of Salmonella in poultry: the relationships between sampling and cultural methodology, prevalence and numbers of cells, and the implications of serotype and subtype issues. Minimizing Salmonella contamination of poultry is not likely to reduce human salmonellosis acquired from exposure to contaminated chicken until these issues are confronted more systematically.

  12. Minimal flavour violation and SU(5)-unification

    Energy Technology Data Exchange (ETDEWEB)

    Barbieri, Riccardo, E-mail: barbieri@sns.it; Senia, Fabrizio, E-mail: fabrizio.senia@sns.it [Scuola Normale Superiore and INFN, Piazza dei Cavalieri 7, 56126, Pisa (Italy)

    2015-12-17

    Minimal flavour violation in its strong or weak versions, based on U(3){sup 3} and U(2){sup 3}, respectively, allows suitable extensions of the standard model at the TeV scale to comply with current flavour constraints in the quark sector. Here we discuss considerations analogous to minimal flavour violation (MFV) in the context of SU(5)-unification, showing the new effects/constraints that arise both in the quark and in the lepton sector, where quantitative statements can be made controlled by the CKM matrix elements. The case of supersymmetry is examined in detail as a particularly motivated example. Third generation sleptons and neutralinos in the few hundred GeV range are shown to be compatible with current constraints.

  13. Minimally invasive techniques in Acoustic Neurinoma Microneurosurgery

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The present report should summarize our experience using minimally invasive techniques in acoustic neurinoma surgery at the Neurosurgical Department,University of Vienna,Austria .Based on the experience of about 687 cases ub a 20year time period our mostly used techniques will be presented. This is a minimal innvasive individual adapted approach,specified intraoperative strategy and dissection tech-niques (e.g.water jet dissection,ultrasonic aspirator CUSA),the use of neuronavigational systems and the use of endoscope assisted surgery.With respect to the Limited space of place precise citations to further textbooks of the authors handling with this topic will be given. Finally our results using these techniques are presented and further future perspectives in the treatment of these pathology(radiosurgery)will be dis-cussed.

  14. Minimal Left-Right Symmetric Dark Matter.

    Science.gov (United States)

    Heeck, Julian; Patra, Sudhanwa

    2015-09-18

    We show that left-right symmetric models can easily accommodate stable TeV-scale dark matter particles without the need for an ad hoc stabilizing symmetry. The stability of a newly introduced multiplet either arises accidentally as in the minimal dark matter framework or comes courtesy of the remaining unbroken Z_{2} subgroup of B-L. Only one new parameter is introduced: the mass of the new multiplet. As minimal examples, we study left-right fermion triplets and quintuplets and show that they can form viable two-component dark matter. This approach is, in particular, valid for SU(2)×SU(2)×U(1) models that explain the recent diboson excess at ATLAS in terms of a new charged gauge boson of mass 2 TeV.

  15. Minimal Left-Right Dark Matter

    CERN Document Server

    Heeck, Julian

    2015-01-01

    We show that left-right-symmetric models can easily accommodate stable TeV-scale dark matter particles. The stability of a newly introduced multiplet arises either accidentally as in the Minimal Dark Matter framework or comes courtesy of the remaining unbroken $\\mathbb{Z}_2$ subgroup of $B-L$. As a minimal example we study left-right fermion triplets and quintuplets and show that they can form viable two-component dark matter. This approach is in particular valid for $SU(2)\\times SU(2)\\times U(1)$ models that explain the recent diboson excess at ATLAS in terms of a new charged gauge boson of mass 2 TeV.

  16. Towards synthesis of a minimal cell.

    Science.gov (United States)

    Forster, Anthony C; Church, George M

    2006-01-01

    Construction of a chemical system capable of replication and evolution, fed only by small molecule nutrients, is now conceivable. This could be achieved by stepwise integration of decades of work on the reconstitution of DNA, RNA and protein syntheses from pure components. Such a minimal cell project would initially define the components sufficient for each subsystem, allow detailed kinetic analyses and lead to improved in vitro methods for synthesis of biopolymers, therapeutics and biosensors. Completion would yield a functionally and structurally understood self-replicating biosystem. Safety concerns for synthetic life will be alleviated by extreme dependence on elaborate laboratory reagents and conditions for viability. Our proposed minimal genome is 113 kbp long and contains 151 genes. We detail building blocks already in place and major hurdles to overcome for completion.

  17. Topological minimally entangled states via geometric measure

    Science.gov (United States)

    Buerschaper, Oliver; García-Saez, Artur; Orús, Román; Wei, Tzu-Chieh

    2014-11-01

    Here we show how the Minimally Entangled States (MES) of a 2d system with topological order can be identified using the geometric measure of entanglement. We show this by minimizing this measure for the doubled semion, doubled Fibonacci and toric code models on a torus with non-trivial topological partitions. Our calculations are done either quasi-exactly for small system sizes, or using the tensor network approach in Orús et al (arXiv:1406.0585) for large sizes. As a byproduct of our methods, we see that the minimisation of the geometric entanglement can also determine the number of Abelian quasiparticle excitations in a given model. The results in this paper provide a very efficient and accurate way of extracting the full topological information of a 2d quantum lattice model from the multipartite entanglement structure of its ground states.

  18. Minimizing ADMs on WDM Directed Fiber Trees

    Institute of Scientific and Technical Information of China (English)

    ZHOU FengFeng (周丰丰); CHEN GuoLiang (陈国良); XU YinLong (许胤龙); GU Jun (顾钧)

    2003-01-01

    This paper proposes a polynomial-time algorithm for Minimum WDM/SONET Add/Drop Multiplexer Problem (MADM) on WDM directed fiber trees whether or not wavelength converters are used. It runs in time O(m2n), where n and m are the number of nodes of the tree and the number of the requests respectively. Incorporating T. Erlebach et al.'s work into the proposed algorithm, it also reaches the lower bound of the required wavelengths with greedy algorithms for the case without wavelength converters. Combined with some previous work, the algorithm reduces the number of required wavelengths greatly while using minimal number of ADMs for the case with limited wavelength converters. The experimental results show the minimal number of required ADMs on WDM directed fiber trees.

  19. Report on the Radiation Effects Testing of the Infrared and Optical Transition Radiation Camera Systems

    Energy Technology Data Exchange (ETDEWEB)

    Holloway, Michael Andrew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-04-20

    Presented in this report are the results tests performed at Argonne National Lab in collaboration with Los Alamos National Lab to assess the reliability of the critical 99Mo production facility beam monitoring diagnostics. The main components of the beam monitoring systems are two cameras that will be exposed to radiation during accelerator operation. The purpose of this test is to assess the reliability of the cameras and related optical components when exposed to operational radiation levels. Both X-ray and neutron radiation could potentially damage camera electronics as well as the optical components such as lenses and windows. This report covers results of the testing of component reliability when exposed to X-ray radiation. With the information from this study we provide recommendations for implementing protective measures for the camera systems in order to minimize the occurrence of radiation-induced failure within a ten month production run cycle.

  20. An algorithm for minimization of quantum cost

    OpenAIRE

    Banerjee, Anindita; Pathak, Anirban

    2009-01-01

    A new algorithm for minimization of quantum cost of quantum circuits has been designed. The quantum cost of different quantum circuits of particular interest (eg. circuits for EPR, quantum teleportation, shor code and different quantum arithmetic operations) are computed by using the proposed algorithm. The quantum costs obtained using the proposed algorithm is compared with the existing results and it is found that the algorithm has produced minimum quantum cost in all cases.

  1. Smooth GERBS, orthogonal systems and energy minimization

    Science.gov (United States)

    Dechevsky, Lubomir T.; Zanaty, Peter

    2013-12-01

    New results are obtained in three mutually related directions of the rapidly developing theory of generalized expo-rational B-splines (GERBS) [7, 6]: closed-form computability of C∞-smooth GERBS in terms of elementary and special functions, Hermite interpolation and least-squares best approximation via smooth GERBS, energy minimizing properties of smooth GERBS similar to those of the classical cubic polynomial B-splines.

  2. Heroin-associated anthrax with minimal morbidity.

    Science.gov (United States)

    Black, Heather; Chapman, Ann; Inverarity, Donald; Sinha, Satyajit

    2017-03-08

    In 2010, during an outbreak of anthrax affecting people who inject drugs, a heroin user aged 37 years presented with soft tissue infection. He subsequently was found to have anthrax. We describe his management and the difficulty in distinguishing anthrax from non-anthrax lesions. His full recovery, despite an overall mortality of 30% for injectional anthrax, demonstrates that some heroin-related anthrax cases can be managed predominately with oral antibiotics and minimal surgical intervention.

  3. Minimally Invasive Procedures for Nasal Aesthetics

    OpenAIRE

    Alessio Redaelli; Pietro Limardo

    2012-01-01

    Nose has an important role in the aesthetics of face. It is easy to understand the reason of the major interest that has revolved around the correction of its imperfections for several centuries, or even from the ancient times. In the last decade, all the surgical or medical minimal-invasive techniques evolved exponentially. The techniques of rejuvenation and corrections of nasal imperfections did not escape this development that is much widespread in the medicine of the third millennium. In ...

  4. Geometric Measure Theory and Minimal Surfaces

    CERN Document Server

    Bombieri, Enrico

    2011-01-01

    W.K. ALLARD: On the first variation of area and generalized mean curvature.- F.J. ALMGREN Jr.: Geometric measure theory and elliptic variational problems.- E. GIUSTI: Minimal surfaces with obstacles.- J. GUCKENHEIMER: Singularities in soap-bubble-like and soap-film-like surfaces.- D. KINDERLEHRER: The analyticity of the coincidence set in variational inequalities.- M. MIRANDA: Boundaries of Caciopoli sets in the calculus of variations.- L. PICCININI: De Giorgi's measure and thin obstacles.

  5. Optimal Investment Strategy to Minimize Occupation Time

    CERN Document Server

    Bayraktar, Erhan

    2008-01-01

    We find the optimal investment strategy to minimize the expected time that an individual's wealth stays below zero, the so-called {\\it occupation time}. The individual consumes at a constant rate and invests in a Black-Scholes financial market consisting of one riskless and one risky asset, with the risky asset's price process following a geometric Brownian motion. We also consider an extension of this problem by penalizing the occupation time for the degree to which wealth is negative.

  6. Robots for minimally invasive diagnosis and intervention

    OpenAIRE

    Huda, Nazmul; YU, Hongnian; Cang, Shuang

    2016-01-01

    Minimally invasive diagnosis and interventions provide many benefits such as higher efficiency, safer, minimum pain, quick recovery etc. over conventional way for many procedures. Large robots such as da-Vinci are being used in this purpose, whereas research of miniature robots for laparoscopic and endoscopic use, is growing in the recent years. A comprehensive literature search is performed using keywords’ laparoscopic robot, capsule endoscope, surgical medical robot etc. primarily for the t...

  7. Autonomous Preservation Tools in Minimal Effort Ingest

    DEFF Research Database (Denmark)

    Jurik, Bolette Ammitzbøll; Blekinge, Asger Askov; Andersen, Thorbjørn Ravn

    2016-01-01

    This poster presents the concept of Autonomous Preservation Tools, as developed by the State and University Library, Denmark. The work expands the idea of Minimal Effort Ingest, where most preservation actions such as Quality Assurance and enrichment of the digital objects are performed after...... content is ingested for preservation, rather than before. We present our Newspaper Digitisation Project as a case-study of real-world implementations of Autonomous Preservation Tools....

  8. Finite Type Non—Minimal Submanifolds

    Institute of Scientific and Technical Information of China (English)

    宋鸿藻; 吴报强

    1992-01-01

    The notion of finite type xubmanifolds was introduced by B.Y.Chen.In this paper we consider the characteristics and the classifications of finite type non-minimal submanifolds.The characteristic theorems of 2-type Chen submanifolds、mass-symmetric hypersurfaces and Dupin hypersurfaces in Esm are obtained.The classification theorems of 3-type hypersurfaces and null 2-type curves in Esm are also proved.

  9. Isolated subtalar arthrodesis through minimal incision surgery.

    Science.gov (United States)

    Carranza-Bencano, A; Tejero-García, S; Del Castillo-Blanco, G; Fernández-Torres, J J; Alegrete-Parra, A

    2013-08-01

    In recent years there has been an increase in the use of minimally invasive techniques, such as arthroscopy, percutaneous, and minimally invasive incisions, for foot and ankle surgery. The purpose of this study was to analyze the fusion rate and clinical results of isolated subtalar arthrodesis (ISA) using the novel and original technique of minimal incision surgery (MIS). There were a total of 77 feet in 76 patients who underwent ISA and were followed for 50 months on average (range, 15-108). The first 30 cases were evaluated retrospectively, and 47 cases were evaluated prospectively. MIS without tourniquet was used in all cases and fusion was assessed radiographically and clinically. Clinical outcome measures used were the Angus and Cowell Scoring System, AOFAS Ankle-Hindfoot, the SF-36, and a patient satisfaction questionnaire 12 months after the intervention. Radiographic and clinical consolidation was achieved in 92% of cases. Main outcomes were "good" in 57 patients as determined by the Angus and Cowell criteria, with 13 "fair" and 7 "poor" results. In the prospective group, AOFAS scores improved by 47.6 points (95% CI: 50.7-42.5) 12 months after surgical intervention. SF-36 outcomes improved by 14.5 points (95% CI: 11.58-17.31) in the mental summary component and 4.2 points (95% CI: 2.2-6.1) in the physical summary component. We recorded no cases of early complications such as wound infections, neurovascular damage, or delayed wound healing. To our knowledge, the present series represents the largest study on subtalar arthrodesis using minimally invasive surgery. The data obtained showed a similar rate of bony union and clinical outcomes compared with the literature, but without early wound complications. ISA using the MIS technique was a good option for patients at greater risk of wound healing complications. Level IV, case series.

  10. Minimally invasive dentistry: a review and update.

    Science.gov (United States)

    Brostek, Andrew M; Bochenek, Andrew J; Walsh, Laurence J

    2006-06-01

    The term "Minimal Invasive (MI) Dentistry" can best be defined as the management of caries with a biological approach, rather than with a traditional (surgical) operative dentistry approach. Where operative dentistry is required, this is now carried out in the most conservative manner with minimal destruction of tooth structure. This new approach to caries management changes the emphasis from diagnosing carious lesions as cavities (and a repeating cycle of restorations), to one of diagnosing the oral ecological imbalance and effecting biological changes in the biofilm. The goal of MI is to stop the disease process and then to restore lost tooth structure and function, maximizing the healing potential of the tooth. The thought process which underpins this new minimal invasive approach can be organized into three main categories: (1) Recognize, which means identify patient caries risk, (2) Remineralize, which means prevent caries and reverse non-cavitated caries, and (3) Repair, which means control caries activity, maximize healing and repair the damage. The disease of dental caries is not just demineralization, but a process of repeated demineralization cycles caused by an imbalance in the ecological and chemical equilibrium of the biofilm /tooth interface (the ecological plaque hypothesis). Dietary and lifestyle patterns, especially carbohydrate frequency, water intake and smoking, play an important role in changing the biofilm ecology and pathogenicity. Tools for chairside assessment of saliva and plaque, allow risk to be assessed and patient compliance monitored. The remineralizing properties of saliva can be enhanced using materials which release biologically available calcium, phosphate and fluoride ions (CPP-ACP and CPP-ACFP). Use of biocides can also alter the pathogenic properties of plaque. Use of these MI treatment protocols, can repair early lesions and improve patient understanding and compliance. This review article introduces some of the key concepts

  11. The minimal genus problem in rational surfaces

    Institute of Scientific and Technical Information of China (English)

    ZHAO; Xu'an

    2006-01-01

    [1]Kronheimer P B,Mrowka T S.The genus of embedding surfaces in the projective plane.Math Res Lett,1994,1:797-808[2]Lawson T.The minimal genus problem.Expo Math,1997,15:385-431[3]Li B H.Representing nonnegative homology classes of CP2#n-CP2 by minimal genus smooth embedding.Trans Amer Soc,1999,352(9):4155-4169[4]Ruberman D.The minimal genus of an embedding surface of non-negative square in a rational surface.Turkish J Math,1996,20:129-133[5]Wall C T C.On the orthogonal groups of unimodular quadratic forms Ⅱ.Crelle Jour,1963,213:122-136[6]Gao H.Representing homology classes of almost definite 4-manifolds.Topology Appl,1993,52:109-120[7]Kikuchi K.Positive 2-spheres in 4-manifolds of signature (1,n).Pacific Jour Math,1993,160:245-258[8]Li B H,Li T J.Smooth minimal genera for small negative classes in CP2#n-CP2 with n ≤ 9.Topology Appl,2003,132(1):1-15[9]Friedman R,Morgan J.On the diffeomorphism types of certain algebraic surfaces.Journal of Differential Geometry,1988,27(3):371-398[10]Kac V G.Infinite-Dimensional Lie Algebras.3rd ed.Cambridge:Cambridge University Press,1990[11]Li T J,Liu A.Symplectic structure on ruled surfaces and generalized adjunction formula.Math Res Lett,1995,2:453-471

  12. Minimal factorizations of permutations into star transpositions

    OpenAIRE

    Irving, J.; Rattan, Amarpreet

    2009-01-01

    International audience; We give a compact expression for the number of factorizations of any permutation into a minimal number of transpositions of the form $(1 i)$. Our result generalizes earlier work of Pak ($\\textit{Reduced decompositions of permutations in terms of star transpositions, generalized catalan numbers and k-ary trees}$, Discrete Math. $\\textbf{204}$:329―335, 1999) in which substantial restrictions were placed on the permutation being factored.; Nous présentons une expression c...

  13. Minimal Change and Bounded Incremental Parsing

    CERN Document Server

    Wiren, M

    1994-01-01

    Ideally, the time that an incremental algorithm uses to process a change should be a function of the size of the change rather than, say, the size of the entire current input. Based on a formalization of ``the set of things changed'' by an incremental modification, this paper investigates how and to what extent it is possible to give such a guarantee for a chart-based parsing framework and discusses the general utility of a minimality notion in incremental processing.

  14. Mesonic spectroscopy of Minimal Walking Technicolor

    CERN Document Server

    Del Debbio, Luigi; Patella, Agostino; Pica, Claudio; Rago, Antonio

    2010-01-01

    We investigate the structure and the novel emerging features of the mesonic non-singlet spectrum of the Minimal Walking Technicolor (MWT) theory. Precision measurements in the nonsinglet pseudoscalar and vector channels are compared to the expectations for an IR-conformal field theory and a QCD-like theory. Our results favor a scenario in which MWT is (almost) conformal in the infrared, while spontaneous chiral symmetry breaking seems less plausible.

  15. Reaction torque minimization techniques for articulated payloads

    Science.gov (United States)

    Kral, Kevin; Aleman, Roberto M.

    1988-01-01

    Articulated payloads on spacecraft, such as antenna telemetry systems and robotic elements, impart reaction torques back into the vehicle which can significantly affect the performance of other payloads. This paper discusses ways to minimize the reaction torques of articulated payloads through command-shaping algorithms and unique control implementations. The effects of reaction torques encountered on Landsat are presented and compared with simulated and measured data of prototype systems employing these improvements.

  16. MINIMAL FUZZY MICROCONTROLLER IMPLEMENTATION FOR DIDACTIC APPLICATIONS

    OpenAIRE

    F. Lara-Rojo; E. N. Sánchez; D. Zaldívar-Navarro

    2003-01-01

    Fuzzy techniques have been successfully used in control in several fields, and engineers and researchers are today considering fuzzy logic algorithms in order to implement intelligent functions in embedded systems. We have started to develop a set of teaching tools to support our courses on intelligent control. Low cost implementations of didactic systems are particularly important in developing countries. In this paper we present the implementation of a minimal PD fuzzy four-rule algorithm i...

  17. The Minimal Geometric Deformation Approach Extended

    CERN Document Server

    Casadio, Roberto; da Rocha, Roldao

    2015-01-01

    The minimal geometric deformation approach was introduced in order to study the exterior space-time around spherically symmetric self-gravitating systems, like stars or similar astrophysical objects as well, in the Randall-Sundrum brane-world framework. A consistent extension of this approach is developed here, which contains modifications of both the time component and the radial component of a spherically symmetric metric. A modified Schwarzschild geometry is obtained as an example of its simplest application.

  18. Next to new minimal standard model

    Energy Technology Data Exchange (ETDEWEB)

    Haba, Naoyuki [Graduate School of Science and Engineering, Shimane University, Matsue, Shimane 690-8504 (Japan); Department of Physics, Faculty of Science, Hokkaido University, Sapporo, Hokkaido 060-0810 (Japan); Kaneta, Kunio [Department of Physics, Faculty of Science, Hokkaido University, Sapporo, Hokkaido 060-0810 (Japan); Kavli IPMU (WPI), The University of Tokyo, Kashiwa, Chiba 277-8568 (Japan); Department of Physics, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043 (Japan); Takahashi, Ryo [Department of Physics, Faculty of Science, Hokkaido University, Sapporo, Hokkaido 060-0810 (Japan)

    2014-06-27

    We suggest a minimal extension of the standard model, which can explain current experimental data of the dark matter, small neutrino masses and baryon asymmetry of the universe, inflation, and dark energy, and achieve gauge coupling unification. The gauge coupling unification can explain the charge quantization, and be realized by introducing six new fields. We investigate the vacuum stability, coupling perturbativity, and correct dark matter abundance in this model by use of current experimental data.

  19. Esophageal surgery in minimally invasive era

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    The widespread popularity of new surgical technologiessuch as laparoscopy, thoracoscopy and robotics has ledmany surgeons to treat esophageal diseases with thesemethods. The expected benefits of minimally invasive surgery (MIS) mainly include reductions of postoperativecomplications, length of hospital stay, and pain andbetter cosmetic results. All of these benefits couldpotentially be of great interest when dealing with theesophagus due to the potentially severe complicationsthat can occur after conventional surgery. Moreover,robotic platforms are expected to reduce many of thedifficulties encountered during advanced laparoscopicand thoracoscopic procedures such as anastomoticreconstructions,accurate lymphadenectomies, andvascular sutures. Almost all esophageal diseases areapproachable in a minimally invasive way, includingdiverticula, gastro-esophageal reflux disease, achalasia,perforations and cancer. Nevertheless, while the limitsof MIS for benign esophageal diseases are mainlytechnical issues and costs, oncologic outcomes remainthe cornerstone of any procedure to cure malignancies,for which the long-term results are critical. Furthermore,many of the minimally invasive esophageal operationsshould be compared to pharmacologic interventionsand advanced pure endoscopic procedures; such acomparison requires a difficult literature analysis andleads to some confounding results of clinical trials. Thisreview aims to examine the evidence for the use of MISin both malignancies and more common benign diseaseof the esophagus, with a particular emphasis on futuredevelopments and ongoing areas of research.

  20. [Minimally Invasive Treatment of Esophageal Benign Diseases].

    Science.gov (United States)

    Inoue, Haruhiro

    2016-07-01

    As a minimally invasive treatment of esophageal achalasia per-oral endoscopic myotomy( POEM) was developed in 2008. More than 1,100 cases of achalasia-related diseases received POEM. Success rate of the procedure was more than 95%(Eckerdt score improvement 3 points and more). No serious( Clavian-Dindo classification III b and more) complication was experienced. These results suggest that POEM becomes a standard minimally invasive treatment for achalasia-related diseases. As an off-shoot of POEM submucosal tumor removal through submucosal tunnel (per-oral endoscopic tumor resection:POET) was developed and safely performed. Best indication of POET is less than 5 cm esophageal leiomyoma. A novel endoscopic treatment of gastroesophageal reflux disease (GERD) was developed. Anti-reflux mucosectomy( ARMS) is nearly circumferential mucosal reduction of gastric cardia mucosa. ARMS is performed in 56 consecutive cases of refractory GERD. No major complications were encountered and excellent clinical results. Best indication of ARMS is a refractory GERD without long sliding hernia. Longest follow-up case is more than 10 years. Minimally invasive treatments for esophageal benign diseases are currently performed by therapeutic endoscopy.