#### Sample records for linear relationship exists

1. Staff turnover in hotels : exploring the quadratic and linear relationships.

Mohsin, A.; Lengler, J.F.B.; Aguzzoli, R.L.

2015-01-01

The aim of this study is to assess whether the relationship between intention to leave the job and its antecedents is quadratic or linear. To explore those relationships a theoretical model (see Fig. 1) and eight hypotheses are proposed. Each linear hypothesis is followed by an alternative quadratic hypothesis. The alternative hypotheses propose that the relationship between the four antecedent constructs and intention to leave the job might not be linear, as the existing literature suggests....

2. Spaghetti Bridges: Modeling Linear Relationships

Kroon, Cindy D.

2016-01-01

Mathematics and science are natural partners. One of many examples of this partnership occurs when scientific observations are made, thus providing data that can be used for mathematical modeling. Developing mathematical relationships elucidates such scientific principles. This activity describes a data-collection activity in which students employ…

3. Linear relationships between cherry tomato traits

Bruno Giacomini Sari

Full Text Available ABSTRACT: The objective of this study was to identify the linear relationship between cherry tomato yield components. Two uniformity trials, without treatments, were conducted on Lilli cherry tomato plants in a plastic greenhouse during the 2014 spring/summer season, with the plants in two stems. Variables observed for each plant were mean fruit length, mean fruit width, mean fruit weight, number of bunches, number of fruits per bunch, total number of fruits, and total fruit weight; a Pearson's correlation matrix was used to estimate the relationship between the variables. Path analysis was then performed considering total fruit weight as the main variable and the remaining variables as explanatory. Due to the severe multicollinearity, the variable 'number of fruits per bunch' was eliminated. Pearson's correlation coefficients were significant between explanatory and main variables. Mean fruit weight has a low cause-and-effect relationship with the total weight of fruits produced. A low cause-and-effect relationship was also observed between number of fruits and number of bunches. Cherry tomato productivity is directly related to the number of fruits per plant.

4. Why Choose Online Learning: Relationship of Existing Factors and Chronobiology

Luo, Yi; Pan, Rui; Choi, Jea H.; Mellish, Linda; Strobel, Johannes

2011-01-01

Existing research on choice of online learning utilized factors such as perceived level of control, independence, and satisfaction, yet the relationship among these factors is under-researched. Due to the value of "learning anytime," biological factors underlying "choice of time" might provide additional insights. This article…

5. Game Theory and its Relationship with Linear Programming Models ...

Game Theory and its Relationship with Linear Programming Models. ... This paper shows that game theory and linear programming problem are closely related subjects since any computing method devised for ... AJOL African Journals Online.

6. The Existence of Overall Satisfaction in Service Customer Relationships

Zulganef Zulganef

2006-09-01

Full Text Available Garbarino and Johnson (1999 find that there is no correlation between overall satisfaction and loyalty in the field of customer relationship. Their finding indicates that satisfaction is no longer an important issue in managing service organizations. This research investigates the existence of satisfaction in service organizations, which have relationships with customers. Contrary to Garbarino and Johnson’s (1999 finding, this research finds that overall satisfaction, through commitment, has a relationship with loyalty. Hence, customer satisfaction is still a main issue with respect to managing service organizations, especially service organizations that have customer-relationship strategy. Survey method was conducted to test 12 hypotheses, and the sample of this research is customers of credit cardholders and supermarket cardholders. Sample size is 382 consisting of 196 (51.3% credit cardholders and 186 (48.7% supermarket cardholders. Data were analyzed using two-step structural equation modelling technique. In addition, this research also shows that investigators and managers should pay attention to affects, because affects have a unique role in relationship customer behavior.

7. Return-Volatility Relationship: Insights from Linear and Non-Linear Quantile Regression

D.E. Allen (David); A.K. Singh (Abhay); R.J. Powell (Robert); M.J. McAleer (Michael); J. Taylor (James); L. Thomas (Lyn)

2013-01-01

textabstractThe purpose of this paper is to examine the asymmetric relationship between price and implied volatility and the associated extreme quantile dependence using linear and non linear quantile regression approach. Our goal in this paper is to demonstrate that the relationship between the

8. Testing the existence of optical linear polarization in young brown dwarfs

Manjavacas, E.; Miles-Páez, P. A.; Zapatero-Osorio, M. R.; Goldman, B.; Buenzli, E.; Henning, T.; Pallé, E.; Fang, M.

2017-07-01

Linear polarization can be used as a probe of the existence of atmospheric condensates in ultracool dwarfs. Models predict that the observed linear polarization increases with the degree of oblateness, which is inversely proportional to the surface gravity. We aimed to test the existence of optical linear polarization in a sample of bright young brown dwarfs, with spectral types between M6 and L2, observable from the Calar Alto Observatory, and cataloged previously as low gravity objects using spectroscopy. Linear polarimetric images were collected in I and R band using CAFOS at the 2.2-m telescope in Calar Alto Observatory (Spain). The flux ratio method was employed to determine the linear polarization degrees. With a confidence of 3σ, our data indicate that all targets have a linear polarimetry degree in average below 0.69 per cent in the I band, and below 1.0 per cent in the R band, at the time they were observed. We detected significant (I.e. P/σ ≥ 3) linear polarization for the young M6 dwarf 2MASS J04221413+1530525 in the R band, with a degree of p* = 0.81 ± 0.17 per cent.

9. Using system theory and energy methods to prove existence of non-linear PDE's

Zwart, H.J.

2015-01-01

In this discussion paper we present an idea of combining techniques known from systems theory with energy estimates to show existence for a class of non-linear partial differential equations (PDE's). At the end of the paper a list of research questions with possible approaches is given.

10. Linear free energy relationships in glass corrosion

Abrajano, T.A. Jr.; Bates, J.K.; Bohlke, J.K.

1988-01-01

Various theoretical models that have been proposed to correlate glass durability to their composition for a wide variety of silicate, borosilicate, and aluminosilicate glasses are examined. Comparisons are made between the predictions of these models and those of an empirical formulation extracted from existing data in the present work. The empirical approach provides independent confirmation of the relative accuracy of the silica release rate predictions of the different theoretical models in static leaching systems. Extension of the empirical approach used in this work are discussed. 23 refs., 2 figs., 1 tab

11. Non-monotone positive solutions of second-order linear differential equations: existence, nonexistence and criteria

Mervan Pašić

2016-10-01

Full Text Available We study non-monotone positive solutions of the second-order linear differential equations: $(p(tx'' + q(t x = e(t$, with positive $p(t$ and $q(t$. For the first time, some criteria as well as the existence and nonexistence of non-monotone positive solutions are proved in the framework of some properties of solutions $\\theta (t$ of the corresponding integrable linear equation: $(p(t\\theta''=e(t$. The main results are illustrated by many examples dealing with equations which allow exact non-monotone positive solutions not necessarily periodic. Finally, we pose some open questions.

12. The Relationship among Localization Skill, Existence Constancy and Object Permanence.

Townes-Rosenwein, Linda

Two component skills of object permanence were studied: existence constancy -- the infants' ability to expect that an object continues to exist after it is hidden, and localization skill -- infants' ability to search in the correct place for a hidden object. Contradictions within the literature may occur because of task lability caused by failure…

13. On the existence of tunneling bounce solutions in piecewise linear potentials

Dutta, Koushik; Hector, Cecelie; Konstandin, Thomas; Vaudrevange, Pascal M.; Westphal, Alexander

2012-02-01

Coleman tunneling in a general scalar potential with two non-degenerate minima is known to have an approximation in terms of a piecewise linear triangular-shaped potential with sharp 'kinks' at the place of the local minima. This approximate potential has a regime where the existence of the bounce solution needs the scalar field to 'wait' for some amount of Euclidean time at one of the 'kinks'. We discuss under which circumstances the correct bounce action can be consistently obtained as the limiting case of a regular scalar potential where 'kinks' are resolved as locally smooth 'cap' regions. (orig.)

14. Does any relationship exist between self reported gingival bleeding ...

Conclusion: Data from this survey revealed an established relationship between gingival bleeding, perceived dental and gingival health, tooth brushing force, professional instruction on tooth brushing, perception of the condition of teeth in relation to daily tooth brushing, worry about the color of gingiva, and satisfaction with ...

15. Commissioning and Acceptance Testing of the existing linear accelerator upgraded to volumetric modulated arc therapy

Varadharajan, Ekambaram; Ramasubramanian, Velayudham

2013-01-01

Aim The RapidArc commissioning and Acceptance Testing program will test and ensure accuracy in DMLC position, precise dose-rate control during gantry rotation and accurate control of gantry speed. Background Recently, we have upgraded our linear accelerator capable of performing IMRT which was functional from 2007 with image guided RapidArc facility. The installation of VMAT in the existing linear accelerator is a tedious process which requires many quality assurance procedures before the proper commissioning of the facility and these procedures are discussed in this study. Materials and methods Output of the machine at different dose rates was measured to verify its consistency at different dose rates. Monitor and chamber linearity at different dose rates were checked. DMLC QA comprising of MLC transmission factor measurement and dosimetric leaf gap measurements were performed using 0.13 cm3 and 0.65 cm3 Farmer type ionization chamber, dose 1 dosimeter, and IAEA 30 cm × 30 cm × 30 cm water phantom. Picket fence test, garden fence test, tests to check leaf positioning accuracy due to carriage movement, calibration of the leaves, leaf speed stability effects due to the acceleration and deceleration of leaves, accuracy and calibration of leaves in producing complex fields, effects of interleaf friction, etc. were verified using EDR2 therapy films, Vidar scanner, Omnipro accept software, amorphous silicon based electronic portal imaging device and EPIQA software.1–8 Results All the DMLC related quality assurance tests were performed and evaluated by film dosimetry, portal dosimetry and EPIQA.7 Conclusion Results confirmed that the linear accelerator is capable of performing accurate VMAT. PMID:24416566

16. Commissioning and Acceptance Testing of the existing linear accelerator upgraded to volumetric modulated arc therapy.

Varadharajan, Ekambaram; Ramasubramanian, Velayudham

2013-01-01

The RapidArc commissioning and Acceptance Testing program will test and ensure accuracy in DMLC position, precise dose-rate control during gantry rotation and accurate control of gantry speed. Recently, we have upgraded our linear accelerator capable of performing IMRT which was functional from 2007 with image guided RapidArc facility. The installation of VMAT in the existing linear accelerator is a tedious process which requires many quality assurance procedures before the proper commissioning of the facility and these procedures are discussed in this study. Output of the machine at different dose rates was measured to verify its consistency at different dose rates. Monitor and chamber linearity at different dose rates were checked. DMLC QA comprising of MLC transmission factor measurement and dosimetric leaf gap measurements were performed using 0.13 cm(3) and 0.65 cm(3) Farmer type ionization chamber, dose 1 dosimeter, and IAEA 30 cm × 30 cm × 30 cm water phantom. Picket fence test, garden fence test, tests to check leaf positioning accuracy due to carriage movement, calibration of the leaves, leaf speed stability effects due to the acceleration and deceleration of leaves, accuracy and calibration of leaves in producing complex fields, effects of interleaf friction, etc. were verified using EDR2 therapy films, Vidar scanner, Omnipro accept software, amorphous silicon based electronic portal imaging device and EPIQA software.(1-8.) All the DMLC related quality assurance tests were performed and evaluated by film dosimetry, portal dosimetry and EPIQA.(7.) Results confirmed that the linear accelerator is capable of performing accurate VMAT.

17. On linear relationship between shock velocity and particle velocity

Dandache, H.

1986-11-01

We attempt to derive the linear relationship between shock velocity U s and particle velocity U p from thermodynamic considerations, taking into account an ideal gas equation of state and a Mie-Grueneisen equation of state for solids. 23 refs

18. Linear Equating for the NEAT Design: Parameter Substitution Models and Chained Linear Relationship Models

Kane, Michael T.; Mroch, Andrew A.; Suh, Youngsuk; Ripkey, Douglas R.

2009-01-01

This paper analyzes five linear equating models for the "nonequivalent groups with anchor test" (NEAT) design with internal anchors (i.e., the anchor test is part of the full test). The analysis employs a two-dimensional framework. The first dimension contrasts two general approaches to developing the equating relationship. Under a "parameter…

19. Load-Flow in Multiphase Distribution Networks: Existence, Uniqueness, Non-Singularity, and Linear Models

Bernstein, Andrey [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Dall-Anese, Emiliano [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Zhao, Changhong [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Wang, Cong [Ecole Polytechnique Federale de Lausanne (EPFL); Le Boudec, Jean-Yves [Ecole Polytechnique Federale de Lausanne (EPFL)

2018-04-06

This paper considers unbalanced multiphase distribution systems with generic topology and different load models, and extends the Z-bus iterative load-flow algorithm based on a fixed-point interpretation of the AC load-flow equations. Explicit conditions for existence and uniqueness of load-flow solutions are presented. These conditions also guarantee convergence of the load-flow algorithm to the unique solution. The proposed methodology is applicable to generic systems featuring (i) wye connections; (ii) ungrounded delta connections; (iii) a combination of wye-connected and delta-connected sources/loads; and, (iv) a combination of line-to-line and line-to-grounded-neutral devices at the secondary of distribution transformers. Further, a sufficient condition for the non-singularity of the load-flow Jacobian is proposed. Finally, linear load-flow models are derived, and their approximation accuracy is analyzed. Theoretical results are corroborated through experiments on IEEE test feeders.

20. On the existence of tunneling bounce solutions in piecewise linear potentials

Dutta, Koushik; Hector, Cecelie; Konstandin, Thomas; Vaudrevange, Pascal M.; Westphal, Alexander

2012-02-15

Coleman tunneling in a general scalar potential with two non-degenerate minima is known to have an approximation in terms of a piecewise linear triangular-shaped potential with sharp 'kinks' at the place of the local minima. This approximate potential has a regime where the existence of the bounce solution needs the scalar field to 'wait' for some amount of Euclidean time at one of the 'kinks'. We discuss under which circumstances the correct bounce action can be consistently obtained as the limiting case of a regular scalar potential where 'kinks' are resolved as locally smooth 'cap' regions. (orig.)

1. Non linear Euler-Poisson system. Part 1: global existence of low entropy solutions

Cordier, S.

1995-05-01

In this work a 1-D model of electrons and ions plasma is considered. Electrons are supposed to be in Maxwell-Boltzmann thermodynamic equilibrium while ions are described with an isothermal flow model of charged particles submitted to a self-consistent electric field. A collision term between neutral particles and ions simulates the presence of neutral particles. This work demonstrates the existence of low entropy solutions for this simple model with arbitrary initial conditions. Most of the paper is devoted to the demonstration of this theorem and follows the successive steps: construction of a numerical scheme, recall of the classical properties of Riemann problem solutions using Glimm method, uniform estimations for the whole variation norm, and finally, convergence of the constructed solutions towards a low entropy solution for the non-linear Euler/Poisson system. Domains of application for this type of model are listed in the conclusion. (J.S.). 18 refs

2. Structure/property relationships in non-linear optical materials

Cole, J M [Institut Max von Laue - Paul Langevin (ILL), 38 - Grenoble (France); [Durham Univ. (United Kingdom); Howard, J A.K. [Durham Univ. (United Kingdom); McIntyre, G J [Institut Max von Laue - Paul Langevin (ILL), 38 - Grenoble (France)

1997-04-01

The application of neutrons to the study of structure/property relationships in organic non-linear optical materials (NLOs) is described. In particular, charge-transfer effects and intermolecular interactions are investigated. Charge-transfer effects are studied by charge-density analysis and an example of one such investigation is given. The study of intermolecular interactions concentrates on the effects of hydrogen-bonding and an example is given of two structurally similar molecules with very disparate NLO properties, as a result of different types of hydrogen-bonding. (author). 3 refs.

3. On the existence of star products on quotient spaces of linear Hamiltonian torus actions

Herbig, Hans-Christian; Iyengar, Srikanth B.; Pflaum, Markus J.

2009-01-01

that the Koszul complex on the moment map of an effective linear Hamiltonian torus action is acyclic. We rephrase the nonpositivity condition of Arms and Gotay (Adv Math 79(1):43–103, 1990) for linear Hamiltonian torus actions. It follows that reduced spaces of such actions admit continuous star products....

4. Relationship between linear type and fertility traits in Nguni cows.

Zindove, T J; Chimonyo, M; Nephawe, K A

2015-06-01

The objective of the study was to assess the dimensionality of seven linear traits (body condition score, body stature, body length, heart girth, navel height, body depth and flank circumference) in Nguni cows using factor analysis and indicate the relationship between the extracted latent variables and calving interval (CI) and age at first calving (AFC). The traits were measured between December 2012 and November 2013 on 1559 Nguni cows kept under thornveld, succulent karoo, grassland and bushveld vegetation types. Low partial correlations (-0.04 to 0.51), high Kaiser statistic for measure of sampling adequacy scores and significance of the Bartlett sphericity test (P1. Factor 1 included body condition score, body depth, flank circumference and heart girth and represented body capacity of cows. Factor 2 included body length, body stature and navel height and represented frame size of cows. CI and AFC decreased linearly with increase of factor 1. There was a quadratic increase in AFC as factor 2 increased (Pbody capacity and the other to the frame size of the cows. Small-framed cows with large body capacities have shorter CI and AFC.

5. Approximate analytical relationships for linear optimal aeroelastic flight control laws

Kassem, Ayman Hamdy

1998-09-01

This dissertation introduces new methods to uncover functional relationships between design parameters of a contemporary control design technique and the resulting closed-loop properties. Three new methods are developed for generating such relationships through analytical expressions: the Direct Eigen-Based Technique, the Order of Magnitude Technique, and the Cost Function Imbedding Technique. Efforts concentrated on the linear-quadratic state-feedback control-design technique applied to an aeroelastic flight control task. For this specific application, simple and accurate analytical expressions for the closed-loop eigenvalues and zeros in terms of basic parameters such as stability and control derivatives, structural vibration damping and natural frequency, and cost function weights are generated. These expressions explicitly indicate how the weights augment the short period and aeroelastic modes, as well as the closed-loop zeros, and by what physical mechanism. The analytical expressions are used to address topics such as damping, nonminimum phase behavior, stability, and performance with robustness considerations, and design modifications. This type of knowledge is invaluable to the flight control designer and would be more difficult to formulate when obtained from numerical-based sensitivity analysis.

6. The existence of parenting styles in the owner-dog relationship

Herwijnen, Van, Ineke R.; Borg, Van Der, Joanne A.M.; Naguib, Marc; Beerda, Bonne

2018-01-01

Parents interact with children following specific styles, known to influence child development. These styles represent variations in the dimensions of demandingness and responsiveness, resulting in authoritarian, authoritative, permissive or uninvolved parenting. Given the similarities in the parent to child and owner to dog relationships, we determined the extent to which parenting styles exist in the owner to dog relationship using the existing Parenting Styles and Dimensions Questionnaire ...

7. Global existence for a quasi-linear evolution equation with a non-convex energy

Feireisl, Eduard; Petzeltová, Hana

2002-01-01

Roč. 354, č. 4 (2002), s. 1421-1437 ISSN 0002-9947 R&D Projects: GA AV ČR IAA1019002 Keywords : existence of global %initial-boundary value problem Subject RIV: BA - General Mathematics Impact factor: 0.664, year: 2002

8. Existence and uniqueness to the Cauchy problem for linear and semilinear parabolic equations with local conditions⋆

Rubio Gerardo

2011-03-01

Full Text Available We consider the Cauchy problem in ℝd for a class of semilinear parabolic partial differential equations that arises in some stochastic control problems. We assume that the coefficients are unbounded and locally Lipschitz, not necessarily differentiable, with continuous data and local uniform ellipticity. We construct a classical solution by approximation with linear parabolic equations. The linear equations involved can not be solved with the traditional results. Therefore, we construct a classical solution to the linear Cauchy problem under the same hypotheses on the coefficients for the semilinear equation. Our approach is using stochastic differential equations and parabolic differential equations in bounded domains. Finally, we apply the results to a stochastic optimal consumption problem. Nous considérons le problème de Cauchy dans ℝd pour une classe d’équations aux dérivées partielles paraboliques semi linéaires qui se pose dans certains problèmes de contrôle stochastique. Nous supposons que les coefficients ne sont pas bornés et sont localement Lipschitziennes, pas nécessairement différentiables, avec des données continues et ellipticité local uniforme. Nous construisons une solution classique par approximation avec les équations paraboliques linéaires. Les équations linéaires impliquées ne peuvent être résolues avec les résultats traditionnels. Par conséquent, nous construisons une solution classique au problème de Cauchy linéaire sous les mêmes hypothèses sur les coefficients pour l’équation semi-linéaire. Notre approche utilise les équations différentielles stochastiques et les équations différentielles paraboliques dans les domaines bornés. Enfin, nous appliquons les résultats à un problème stochastique de consommation optimale.

9. Assessing Risk in Costing High-energy Accelerators: from Existing Projects to the Future Linear Collider

Lebrun, Philippe

2010-01-01

High-energy accelerators are large projects funded by public money, developed over the years and constructed via major industrial contracts both in advanced technology and in more conventional domains such as civil engineering and infrastructure, for which they often constitute one-of markets. Assessing their cost, as well as the risk and uncertainty associated with this assessment is therefore an essential part of project preparation and a justified requirement by the funding agencies. Stemming from the experience with large circular colliders at CERN, LEP and LHC, as well as with the Main Injector, the Tevatron Collider Experiments and Accelerator Upgrades, and the NOvA Experiment at Fermilab, we discuss sources of cost variance and derive cost risk assessment methods applicable to the future linear collider, through its two technical approaches for ILC and CLIC. We also address disparities in cost risk assessment imposed by regional differences in regulations, procedures and practices.

10. Existence of entire solutions of some non-linear differential-difference equations.

Chen, Minfeng; Gao, Zongsheng; Du, Yunfei

2017-01-01

In this paper, we investigate the admissible entire solutions of finite order of the differential-difference equations [Formula: see text] and [Formula: see text], where [Formula: see text], [Formula: see text] are two non-zero polynomials, [Formula: see text] is a polynomial and [Formula: see text]. In addition, we investigate the non-existence of entire solutions of finite order of the differential-difference equation [Formula: see text], where [Formula: see text], [Formula: see text] are two non-constant polynomials, [Formula: see text], m , n are positive integers and satisfy [Formula: see text] except for [Formula: see text], [Formula: see text].

11. Existence and Linear Stability of Equilibrium Points in the Robe’s Restricted Three-Body Problem with Oblateness

2012-01-01

Full Text Available This paper investigates the positions and linear stability of an infinitesimal body around the equilibrium points in the framework of the Robe’s circular restricted three-body problem, with assumptions that the hydrostatic equilibrium figure of the first primary is an oblate spheroid and the second primary is an oblate body as well. It is found that equilibrium point exists near the centre of the first primary. Further, there can be one more equilibrium point on the line joining the centers of both primaries. Points on the circle within the first primary are also equilibrium points under certain conditions and the existence of two out-of-plane points is also observed. The linear stability of this configuration is examined and it is found that points near the center of the first primary are conditionally stable, while the circular and out of plane equilibrium points are unstable.

12. On the existence of eigenmodes of linear quasi-periodic differential equations and their relation to the MHD continuum

Salat, A.

1981-12-01

The existence of quasi-periodic eigensolutions of a linear second order ordinary differential equation with quasi-periodic coefficient f(ω 1 t,ω 2 t) is investigated numerically and graphically. For sufficiently incommensurate frequencies ω 1 , ω 2 a doubly indexed infinite sequence of eigenvalues and eigenmodes is obtained. The equation considered is a model for the magneto-hydrodynamic 'continuum' in general toroidal geometry. The result suggests that continuum modes exist at least on sufficiently irrational magnetic surfaces. (orig.)

13. Genetic relationships between calving interval and linear type traits in

Genetic correlations between first calving interval (CI) and linear type traits in South African Holstein and Jersey cattle were estimated to assess the possibility of using type information as selection criteria for CI. All linear type traits routinely evaluated under the National Genetic Evaluation Programme (18 for Jersey and 17 ...

14. Comparative Study on Code-based Linear Evaluation of an Existing RC Building Damaged during 1998 Adana-Ceyhan Earthquake

Toprak, A. Emre; Guelay, F. Guelten; Ruge, Peter

2008-01-01

Determination of seismic performance of existing buildings has become one of the key concepts in structural analysis topics after recent earthquakes (i.e. Izmit and Duzce Earthquakes in 1999, Kobe Earthquake in 1995 and Northridge Earthquake in 1994). Considering the need for precise assessment tools to determine seismic performance level, most of earthquake hazardous countries try to include performance based assessment in their seismic codes. Recently, Turkish Earthquake Code 2007 (TEC'07), which was put into effect in March 2007, also introduced linear and non-linear assessment procedures to be applied prior to building retrofitting. In this paper, a comparative study is performed on the code-based seismic assessment of RC buildings with linear static methods of analysis, selecting an existing RC building. The basic principles dealing the procedure of seismic performance evaluations for existing RC buildings according to Eurocode 8 and TEC'07 will be outlined and compared. Then the procedure is applied to a real case study building is selected which is exposed to 1998 Adana-Ceyhan Earthquake in Turkey, the seismic action of Ms = 6.3 with a maximum ground acceleration of 0.28 g It is a six-storey RC residential building with a total of 14.65 m height, composed of orthogonal frames, symmetrical in y direction and it does not have any significant structural irregularities. The rectangular shaped planar dimensions are 16.40 mx7.80 m = 127.90 m 2 with five spans in x and two spans in y directions. It was reported that the building had been moderately damaged during the 1998 earthquake and retrofitting process was suggested by the authorities with adding shear-walls to the system. The computations show that the performing methods of analysis with linear approaches using either Eurocode 8 or TEC'07 independently produce similar performance levels of collapse for the critical storey of the structure. The computed base shear value according to Eurocode is much higher

15. Comparative Study on Code-based Linear Evaluation of an Existing RC Building Damaged during 1998 Adana-Ceyhan Earthquake

Toprak, A. Emre; Gülay, F. Gülten; Ruge, Peter

2008-07-01

Determination of seismic performance of existing buildings has become one of the key concepts in structural analysis topics after recent earthquakes (i.e. Izmit and Duzce Earthquakes in 1999, Kobe Earthquake in 1995 and Northridge Earthquake in 1994). Considering the need for precise assessment tools to determine seismic performance level, most of earthquake hazardous countries try to include performance based assessment in their seismic codes. Recently, Turkish Earthquake Code 2007 (TEC'07), which was put into effect in March 2007, also introduced linear and non-linear assessment procedures to be applied prior to building retrofitting. In this paper, a comparative study is performed on the code-based seismic assessment of RC buildings with linear static methods of analysis, selecting an existing RC building. The basic principles dealing the procedure of seismic performance evaluations for existing RC buildings according to Eurocode 8 and TEC'07 will be outlined and compared. Then the procedure is applied to a real case study building is selected which is exposed to 1998 Adana-Ceyhan Earthquake in Turkey, the seismic action of Ms = 6.3 with a maximum ground acceleration of 0.28 g It is a six-storey RC residential building with a total of 14.65 m height, composed of orthogonal frames, symmetrical in y direction and it does not have any significant structural irregularities. The rectangular shaped planar dimensions are 16.40 m×7.80 m = 127.90 m2 with five spans in x and two spans in y directions. It was reported that the building had been moderately damaged during the 1998 earthquake and retrofitting process was suggested by the authorities with adding shear-walls to the system. The computations show that the performing methods of analysis with linear approaches using either Eurocode 8 or TEC'07 independently produce similar performance levels of collapse for the critical storey of the structure. The computed base shear value according to Eurocode is much higher

16. Linear and Non-Linear Dose-Response Functions Reveal a Hormetic Relationship Between Stress and Learning

Zoladz, Phillip R.; Diamond, David M.

2008-01-01

Over a century of behavioral research has shown that stress can enhance or impair learning and memory. In the present review, we have explored the complex effects of stress on cognition and propose that they are characterized by linear and non-linear dose-response functions, which together reveal a hormetic relationship between stress and learning. We suggest that stress initially enhances hippocampal function, resulting from amygdala-induced excitation of hippocampal synaptic plasticity, as ...

17. Relationship between pelvic and linear body measurements in ...

The aim of this study was to determine pelvic height, width and area and to estimate correlations between these measurements and other external linear body parameters, i.e. body height, shoulder height, chest depth, front quarter width, hindquarter width, rump length and rump slope in Dorper ewes. A total of 332 young ...

18. Re-examining the risk–return relationship in Europe: Linear or non-linear trade-off?

Salvador, Enrique; Floros, Christos; Arago, Vicent

2014-01-01

This paper analyzes the risk–return trade-off in Europe using recent data from 11 European stock markets. After relaxing the linear assumptions in the risk–return relationship by introducing a new approach that considers the current state of the market, we obtain significant evidence for a positive risk–return trade-off for low volatility states. However, this finding is reduced or even non-significant during periods of high volatility. Maintaining the linear assumption over the risk–return t...

19. Non-linear relationship between oxygen uptake and power output in the Astrand nomogram-old data revisited.

Zoladz, J A; Szkutnik, Z; Majerczak, J; Duda, K; Pedersen, P K

2007-06-01

For the last decade there have been considerable discussion concerning the linearity / non-linearity of the oxygen uptake (V(O2)) - power output (W) relationship with strong experimental evidence of non-linearity provided mainly by breath-by-breath measurements. In this study, we attempted to answer the question whether the V(O2) - W relationship in the Astrand nomogram, as presented in the Textbook of Work Physiology, P.-O. Astrand et al. (2003), page 281, based on the Douglas bag method, is indeed linear, as stated by the authors before, or if a change point in V(O2), described by Zoladz et al. (1998) Eur J Appl Physiol 78: 369-377, can possibly be detected in those data. The V(O2) - W data were taken from the Astrand nomogram referenced above and from the Table 9.5 on page 282 in the same reference and tested for the presence of the change point in V(O2), using our two-phase model (see the reference above). In the first phase, a linear V(O2) - W relationship was assumed, whereas in the second one (above the so-called change point) an additional increase in V(O2) above the values expected from the linear model was allowed. It was found that in the data taken from the Astrand nomogram (data for men), as well as in the data taken from the Table 9.5, statistically significant change points in V(O2) were present at the power output of 150 W. The documentation of the presence of a change point in the V(O2) - W relationship in the Astrand data provides further evidence for the existence of a non-linearity in the V(O2) - W relationship in incremental exercise tests of humans, also in V(O2) data based upon the Douglas bag method.

20. Non-linear assessment and deficiency of linear relationship for healthcare industry

Nordin, N.; Abdullah, M. M. A. B.; Razak, R. C.

2017-09-01

This paper presents the development of the non-linear service satisfaction model that assumes patients are not necessarily satisfied or dissatisfied with good or poor service delivery. With that, compliment and compliant assessment is considered, simultaneously. Non-linear service satisfaction instrument called Kano-Q and Kano-SS is developed based on Kano model and Theory of Quality Attributes (TQA) to define the unexpected, hidden and unspoken patient satisfaction and dissatisfaction into service quality attribute. A new Kano-Q and Kano-SS algorithm for quality attribute assessment is developed based satisfaction impact theories and found instrumentally fit the reliability and validity test. The results were also validated based on standard Kano model procedure before Kano model and Quality Function Deployment (QFD) is integrated for patient attribute and service attribute prioritization. An algorithm of Kano-QFD matrix operation is developed to compose the prioritized complaint and compliment indexes. Finally, the results of prioritized service attributes are mapped to service delivery category to determine the most prioritized service delivery that need to be improved at the first place by healthcare service provider.

1. The existence of parenting styles in the owner-dog relationship.

Ineke R van Herwijnen

Full Text Available Parents interact with children following specific styles, known to influence child development. These styles represent variations in the dimensions of demandingness and responsiveness, resulting in authoritarian, authoritative, permissive or uninvolved parenting. Given the similarities in the parent to child and owner to dog relationships, we determined the extent to which parenting styles exist in the owner to dog relationship using the existing Parenting Styles and Dimensions Questionnaire for the parent-child relationship and an adapted version for dog owners. Items on the parenting of children/dogs were rated for applicability on a five-point Likert scale by 518 Dutch dog owning parents. Principal Component Analyses grouped parenting propensities into styles, with some marked differences between the findings for children and dogs. Dog-directed items grouped into an authoritarian-correction orientated style, incorporating variation in demandingness and focussing on correcting a dog for behaviour verbally/physically, and in two styles based on authoritative items. An authoritative-intrinsic value orientated style reflected variation in mainly responsiveness and oriented on the assumed needs and emotions of the animal. A second authoritative-item based style, captured variations in demandingness and responsiveness. We labelled this style authoritative-training orientated, as it orientated on manners in teaching a dog how to behave in social situations. Thus, we defined dog-directed parenting styles and constructed a Dog-Directed Parenting Styles and Dimensions Questionnaire along the lines of the existing theoretical framework on parenting styles. We did not find a dog-directed parenting style of being permissive or uninvolved, which we attribute to a study population of devoted dog owners and our findings should be interpreted with this specific study population in mind. We found evidence of dog-directed parenting styles and provide a

2. The existence of parenting styles in the owner-dog relationship

van der Borg, Joanne A. M.; Naguib, Marc; Beerda, Bonne

2018-01-01

Parents interact with children following specific styles, known to influence child development. These styles represent variations in the dimensions of demandingness and responsiveness, resulting in authoritarian, authoritative, permissive or uninvolved parenting. Given the similarities in the parent to child and owner to dog relationships, we determined the extent to which parenting styles exist in the owner to dog relationship using the existing Parenting Styles and Dimensions Questionnaire for the parent-child relationship and an adapted version for dog owners. Items on the parenting of children/dogs were rated for applicability on a five-point Likert scale by 518 Dutch dog owning parents. Principal Component Analyses grouped parenting propensities into styles, with some marked differences between the findings for children and dogs. Dog-directed items grouped into an authoritarian-correction orientated style, incorporating variation in demandingness and focussing on correcting a dog for behaviour verbally/physically, and in two styles based on authoritative items. An authoritative-intrinsic value orientated style reflected variation in mainly responsiveness and oriented on the assumed needs and emotions of the animal. A second authoritative-item based style, captured variations in demandingness and responsiveness. We labelled this style authoritative-training orientated, as it orientated on manners in teaching a dog how to behave in social situations. Thus, we defined dog-directed parenting styles and constructed a Dog-Directed Parenting Styles and Dimensions Questionnaire along the lines of the existing theoretical framework on parenting styles. We did not find a dog-directed parenting style of being permissive or uninvolved, which we attribute to a study population of devoted dog owners and our findings should be interpreted with this specific study population in mind. We found evidence of dog-directed parenting styles and provide a fundament for determining

3. The existence of parenting styles in the owner-dog relationship.

Herwijnen, Ineke R van; van der Borg, Joanne A M; Naguib, Marc; Beerda, Bonne

2018-01-01

Parents interact with children following specific styles, known to influence child development. These styles represent variations in the dimensions of demandingness and responsiveness, resulting in authoritarian, authoritative, permissive or uninvolved parenting. Given the similarities in the parent to child and owner to dog relationships, we determined the extent to which parenting styles exist in the owner to dog relationship using the existing Parenting Styles and Dimensions Questionnaire for the parent-child relationship and an adapted version for dog owners. Items on the parenting of children/dogs were rated for applicability on a five-point Likert scale by 518 Dutch dog owning parents. Principal Component Analyses grouped parenting propensities into styles, with some marked differences between the findings for children and dogs. Dog-directed items grouped into an authoritarian-correction orientated style, incorporating variation in demandingness and focussing on correcting a dog for behaviour verbally/physically, and in two styles based on authoritative items. An authoritative-intrinsic value orientated style reflected variation in mainly responsiveness and oriented on the assumed needs and emotions of the animal. A second authoritative-item based style, captured variations in demandingness and responsiveness. We labelled this style authoritative-training orientated, as it orientated on manners in teaching a dog how to behave in social situations. Thus, we defined dog-directed parenting styles and constructed a Dog-Directed Parenting Styles and Dimensions Questionnaire along the lines of the existing theoretical framework on parenting styles. We did not find a dog-directed parenting style of being permissive or uninvolved, which we attribute to a study population of devoted dog owners and our findings should be interpreted with this specific study population in mind. We found evidence of dog-directed parenting styles and provide a fundament for determining

4. Existence and Stability of the Periodic Solution with an Interior Transitional Layer in the Problem with a Weak Linear Advection

Nikolay N. Nefedov

2018-01-01

Full Text Available In the paper, we study a singularly perturbed periodic in time problem for the parabolic reaction-advection-diffusion equation with a weak linear advection. The case of the reactive term in the form of a cubic nonlinearity is considered. On the basis of already known results, a more general formulation of the problem is investigated, with weaker sufficient conditions for the existence of a solution with an internal transition layer to be provided than in previous studies. For convenience, the known results are given, which ensure the fulfillment of the existence theorem of the contrast structure. The justification for the existence of a solution with an internal transition layer is based on the use of an asymptotic method of differential inequalities based on the modification of the terms of the constructed asymptotic expansion. Further, sufficient conditions are established to fulfill these requirements, and they have simple and concise formulations in the form of the algebraic equation w(x0,t = 0 and the condition wx(x0,t < 0, which is essentially a condition of simplicity of the root x0(t and ensuring the stability of the solution found. The function w is a function of the known functions appearing in the reactive and advective terms of the original problem. The equation w(x0,t = 0 is a problem for finding the zero approximation x0(t to determine the localization region of the inner transition layer. In addition, the asymptotic Lyapunov stability of the found periodic solution is investigated, based on the application of the so-called compressible barrier method. The main result of the paper is formulated as a theorem.

5. Linear and non-linear dose-response functions reveal a hormetic relationship between stress and learning.

Zoladz, Phillip R; Diamond, David M

2008-10-16

Over a century of behavioral research has shown that stress can enhance or impair learning and memory. In the present review, we have explored the complex effects of stress on cognition and propose that they are characterized by linear and non-linear dose-response functions, which together reveal a hormetic relationship between stress and learning. We suggest that stress initially enhances hippocampal function, resulting from amygdala-induced excitation of hippocampal synaptic plasticity, as well as the excitatory effects of several neuromodulators, including corticosteroids, norepinephrine, corticotropin-releasing hormone, acetylcholine and dopamine. We propose that this rapid activation of the amygdala-hippocampus brain memory system results in a linear dose-response relation between emotional strength and memory formation. More prolonged stress, however, leads to an inhibition of hippocampal function, which can be attributed to compensatory cellular responses that protect hippocampal neurons from excitotoxicity. This inhibition of hippocampal functioning in response to prolonged stress is potentially relevant to the well-described curvilinear dose-response relationship between arousal and memory. Our emphasis on the temporal features of stress-brain interactions addresses how stress can activate, as well as impair, hippocampal functioning to produce a hormetic relationship between stress and learning.

6. Conducting qualitative research in the context of pre-existing peer and collegial relationships.

McDermid, Fiona; Peters, Kath; Jackson, Debra; Daly, John

2014-05-01

To highlight issues and challenges faced in recruitment and interviewing during a study that sought to explore the transition of nurses into academic life and the associated ethical implications. This paper explores the challenges faced in conducting research where the potential participants are peers and workplace colleagues. There are advantages when conducting research with those among whom a pre-existing relationship is shared. However, difficulties can also arise. A methodological review was undertaken. Key database searches included CINAHL, MEDLINE, PubMed, Scopus and Google Scholar using the keywords as search terms. Studies were included if they described in detail issues surrounding qualitative interviewing of peers and colleagues. Management of the issues involved is discussed, with emphasis on boundaries, trust and rapport, the use of self-disclosure and maintaining confidentiality. Research involving peers and colleagues has received relatively little consideration in the literature. There are difficulties associated with interviewing participants with whom the researcher has a pre-existing and ongoing relationship in the same organisation. To ensure ethical conduct, strategies can be used to mitigate negative situations such as issues surrounding dual roles, practising reflexivity, trust and rapport, self-disclosure and confidentiality. It is imperative that dual roles are declared and acknowledged. Researchers need to be mindful of the difficulties that may occur and prioritise participants' confidentiality and privacy.

7. The Relationship between an Emerging Grounded Theory and the Existing Literature: Four phases for consideration

Vivian B. Martin, Ph.D.

2006-06-01

Full Text Available The relationship between grounded theory researchers and the existing literature has become a red herring that even confuses some grounded theorists who have completed a study. Antoinette McCallin’s essay does a commendable job outlining the realities of the research terrain that make proceeding without some exposure to the literature unlikely and ill-advised in most situations. When embarking on my dissertation, I needed to know enough about the literature, both substantive and methodological, to argue for the use of classic grounded theory as opposed to many other choices within my field; yet my study benefited from the necessary tensions between the emerging grounded theory and the existing literature. In this brief essay I propose that the relationship between the existing literature and a developing grounded theory project goes through four discernible phases:noncommittal, comparative, integrative, and, if the analyst can push, a transcendent phase in which the theory is not simply one of a number of theories of a kind within the discipline’s literature. I explain the phases to make more explicit the under-recognized subversive potential of grounded theory to push pass disciplinary boundaries by broadening the ‘relevant’ literature. Barney Glaser has often admonished grounded theory researchers to put off the literature to avoid wasting time and energy with literature that may prove irrelevant. I have not found such literature to be irrelevant as much as limited, and in some cases restricted by what a particular discipline defines as the appropriate literature. Therefore, the question of what literature offers possibilities for literature review and comparisons that would allow for richer knowledge generation. I return to this matter toward the end of the essay.

8. Functions Represented as Linear Sequential Data: Relationships between Presentation and Student Responses

Ayalon, Michal; Watson, Anne; Lerman, Steve

2015-01-01

This study investigates students' ways of attending to linear sequential data in two tasks, and conjectures possible relationships between those ways and elements of the task design. Drawing on the substantial literature about such situations, we focus for this paper on linear rate of change, and on covariation and correspondence approaches to…

9. Existence, stability, and dynamics of harmonically trapped one-dimensional multi-component solitary waves: The near-linear limit

Xu, H.; Kevrekidis, P. G.; Kapitula, T.

2017-06-01

In the present work, we consider a variety of two-component, one-dimensional states in nonlinear Schrödinger equations in the presence of a parabolic trap, inspired by the atomic physics context of Bose-Einstein condensates. The use of Lyapunov-Schmidt reduction methods allows us to identify persistence criteria for the different families of solutions which we classify as (m, n), in accordance with the number of zeros in each component. Upon developing the existence theory, we turn to a stability analysis of the different configurations, using the Krein signature and the Hamiltonian-Krein index as topological tools identifying the number of potentially unstable eigendirections for each branch. A perturbation expansion for the eigenvalue problems associated with nonlinear states found near the linear limit permits us to obtain explicit asymptotic expressions for the eigenvalues. Finally, when the states are found to be unstable, typically by virtue of Hamiltonian Hopf bifurcations, their dynamics is studied in order to identify the nature of the respective instability. The dynamics is generally found to lead to a vibrational evolution over long time scales.

10. Investigating Years 7 to 12 students' knowledge of linear relationships through different contexts and representations

Wilkie, Karina J.; Ayalon, Michal

2018-02-01

A foundational component of developing algebraic thinking for meaningful calculus learning is the idea of "function" that focuses on the relationship between varying quantities. Students have demonstrated widespread difficulties in learning calculus, particularly interpreting and modeling dynamic events, when they have a poor understanding of relationships between variables. Yet, there are differing views on how to develop students' functional thinking over time. In the Australian curriculum context, linear relationships are introduced to lower secondary students with content that reflects a hybrid of traditional and reform algebra pedagogy. This article discusses an investigation into Australian secondary students' understanding of linear functional relationships from Years 7 to 12 (approximately 12 to 18 years old; n = 215) in their approaches to three tasks (finding rate of change, pattern generalisation and interpretation of gradient) involving four different representations (table, geometric growing pattern, equation and graph). From the findings, it appears that these students' knowledge of linear functions remains context-specific rather than becoming connected over time.

11. Does a Relationship Exist Between Lower Body Power and Balance Scores Among Older Adults?

Shim, Andrew; Harr, Brady; Waller, Mike

2018-03-12

Falls are the second-leading cause of unintentional injury and death worldwide. To determine if a relationship exists between lower body power scores and center of pressure (CoP) and limits of stability (LoS) scores. A one-shot case study design (n = 13) was selected for the investigation. All participants were assessed stability scores via computerized posturography to determine CoP and LoS balance scores. Participants stood on a perturbed surface with their eyes open and closed. An experimental stair ramp with a switch mat timing device was used to determine lower body power scores in watts. There was a strong correlation (r = 0.725, p = 0.005) between the posterior (LoS) plane and relative peak power. An intraclass R revealed a strong correlation among the three trials (R = 0.831) performed on the stair ramp. Muscle power output and LoS scores have moderate to strong correlations with balance scores in older adults.

12. The non-linear relationship between body size and function in parrotfishes

Lokrantz, J.; Nyström, M.; Thyresson, M.; Johansson, C.

2008-12-01

Parrotfishes are a group of herbivores that play an important functional role in structuring benthic communities on coral reefs. Increasingly, these fish are being targeted by fishermen, and resultant declines in biomass and abundance may have severe consequences for the dynamics and regeneration of coral reefs. However, the impact of overfishing extends beyond declining fish stocks. It can also lead to demographic changes within species populations where mean body size is reduced. The effect of reduced mean body size on population dynamics is well described in literature but virtually no information exists on how this may influence important ecological functions. The study investigated how one important function, scraping (i.e., the capacity to remove algae and open up bare substratum for coral larval settlement), by three common species of parrotfishes ( Scarus niger, Chlorurus sordidus, and Chlorurus strongylocephalus) on coral reefs at Zanzibar (Tanzania) was influenced by the size of individual fishes. There was a non-linear relationship between body size and scraping function for all species examined, and impact through scraping was also found to increase markedly when fish reached a size of 15 20 cm. Thus, coral reefs which have a high abundance and biomass of parrotfish may nonetheless be functionally impaired if dominated by small-sized individuals. Reductions in mean body size within parrotfish populations could, therefore, have functional impacts on coral reefs that previously have been overlooked.

13. The Relationships between Weight Functions, Geometric Functions,and Compliance Functions in Linear Elastic Fracture Mechanics

Yuan, Rong [Univ. of California, Berkeley, CA (United States)

2007-01-01

Linear elastic fracture mechanics is widely used in industry because it established simple and explicit relationships between the permissible loading conditions and the critical crack size that is allowed in a structure. Stress intensity factors are the above-mentioned functional expressions that relate load with crack size through geometric functions or weight functions. Compliance functions are to determine the crack/flaw size in a structure when optical inspection is inconvenient. As a result, geometric functions, weight functions and compliance functions have been intensively studied to determine the stress intensity factor expressions for different geometries. However, the relations between these functions have received less attention. This work is therefore to investigate the intrinsic relationships between these functions. Theoretical derivation was carried out and the results were verified on single-edge cracked plate under tension and bending. It is found out that the geometric function is essentially the non-dimensional weight function at the loading point. The compliance function is composed of two parts: a varying part due to crack extension and a constant part from the intact structure if no crack exists. The derivative of the compliance function at any location is the product of the geometric function and the weight function at the evaluation point. Inversely, the compliance function can be acquired by the integration of the product of the geometric function and the weight function with respect to the crack size. The integral constant is just the unchanging compliance from the intact structure. Consequently, a special application of the relations is to obtain the compliance functions along a crack once the geometric function and weight functions are known. Any of the three special functions can be derived once the other two functions are known. These relations may greatly simplify the numerical process in obtaining either geometric functions, weight

14. RESEARCH OF EXISTENCE OF RELATIONSHIP BETWEEN VARIABLES BY THE METHOD OF CONDITION-CONSEQUENCE DECOMPOSITION OF EVENTS

V. Dron'

2014-04-01

Full Text Available In the work an algorithm for establishing the existence of relationship between arbitrary socio-economic variables is given. The algorithm is based on the condition-consequence decomposition of events. It involves the construction of event-model and the using two classifications – types of interdependencies between events and types of relationships between their attributes.

15. Social relationships existing among gelada (Theropithecus gelada males in Zoo Zlín

Šárka Hanuláková

2013-01-01

Full Text Available This study was focused on the monitoring of behaviour and complex social relationships existing among gelada (Theropithecus gelada monkeys. The study involved a group of five males that were raised in captivity in the Zoo Zlín – Lešná. Ethological monitoring was performed by means of photographing of the group behaviour of these animals. Studied were the basic forms of social behaviour, i.e. food collection (foraging, free movement, (locomotion observing of the neighbourhood (watching, grooming, climbing on trees, playing, aggressive behaviour (fighting, and resting. The temporary point of view, foraging was the most important time-consuming activity (55.3 ± 2.0 % of the study time; its maximum frequencies occurred in time intervals of 9 and 11 a.m. and 1 to 3 p.m.. The second place was occupied by the locomotion (15.3 ± 4.1 % of the study time and its maximum frequencies were recorded between 9 and 11 a.m. and between 2 and 3 p.m. Grooming was the third most important activity (8.5 ± 4.8 % of the study time. The distribution of periods of rest (7.5 ± 3.1 % of the study time was relatively uniform and its maxima were observed between 10:30 a.m. and 4 p.m. Observing of the neighbourhood and climbing on trees occupied 5.6 ± 3.3 % and 3.6 ± 3.0 % of the time, respectively and playing was the least frequent activity (2.2 ± 9.0 % of the study time, similarly as the aggressive behaviour (2.0 ± 23.0 % of the study time.

16. Structure of Unsteady Partially Premixed Flames and the Existence of State Relationships

Suresh K. Aggarwal

2009-09-01

Full Text Available In this study, we examine the structure and existence of state relationships in unsteady partially premixed flames (PPFs subjected to buoyancy-induced and external perturbations. A detailed numerical model is employed to simulate the steady and unsteady two-dimensional PPFs established using a slot burner under normal and zero-gravity conditions. The coflow velocity is parametrically varied. The methane-air chemistry is modeled using a fairly detailed mechanism that contains 81 elementary reactions and 24 species. Validation of the computational model is provided through comparisons of predictions with nonintrusive measurements. The combustion proceeds in two reaction zones, one a rich premixed zone and the other a nonpremixed zone. These reaction zones are spatially separated, but involve strong interactions between them due to thermochemistry and scalar transport. The fuel is mostly consumed in the premixed zone to produce CO and H2, which are transported to and consumed in the nonpremixed zone. The nonpremixed zone in turn provides heat and H-atoms to the premixed zone. For the range of conditions investigated, the zero-g partially premixed flames exhibit a stable behavior and a remarkably strong resistance to perturbations. In contrast, the corresponding normal-gravity flames exhibit oscillatory behavior at low coflow velocities but a stable behavior at high coflow velocities, and the behavior can be explained in terms of a global and convective instabilities. The effects of coflow and gravity on the flames are characterized through a parameter VR, defined as the ratio of coflow velocity to jet velocity. For VR ≤ 1 (low coflow velocity regime, the structures of both 0- and 1-g flames are strongly sensitive to changes in VR, while they are only mildly affected by coflow in the high coflow velocity regime (VR > 1. In addition, the spatio-temporal characteristics of the 0- and 1-g flames are markedly different in the first regime, but are

17. Competition Experiments as a Means of Evaluating Linear Free Energy Relationships

Mullins, Richard J.; Vedernikov, Andrei; Viswanathan, Rajesh

2004-01-01

The use of competition experiments as a means of evaluating linear free energy relationship in the undergraduate teaching laboratory is reported. The use of competition experiments proved to be a reliable method for the construction of Hammett plots with good correlation providing great flexibility with regard to the compounds and reactions that…

18. Under which climate and soil conditions the plant productivity-precipitation relationship is linear or nonlinear?

Ye, Jian-Sheng; Pei, Jiu-Ying; Fang, Chao

2018-03-01

Understanding under which climate and soil conditions the plant productivity-precipitation relationship is linear or nonlinear is useful for accurately predicting the response of ecosystem function to global environmental change. Using long-term (2000-2016) net primary productivity (NPP)-precipitation datasets derived from satellite observations, we identify >5600pixels in the North Hemisphere landmass that fit either linear or nonlinear temporal NPP-precipitation relationships. Differences in climate (precipitation, radiation, ratio of actual to potential evapotranspiration, temperature) and soil factors (nitrogen, phosphorous, organic carbon, field capacity) between the linear and nonlinear types are evaluated. Our analysis shows that both linear and nonlinear types exhibit similar interannual precipitation variabilities and occurrences of extreme precipitation. Permutational multivariate analysis of variance suggests that linear and nonlinear types differ significantly regarding to radiation, ratio of actual to potential evapotranspiration, and soil factors. The nonlinear type possesses lower radiation and/or less soil nutrients than the linear type, thereby suggesting that nonlinear type features higher degree of limitation from resources other than precipitation. This study suggests several factors limiting the responses of plant productivity to changes in precipitation, thus causing nonlinear NPP-precipitation pattern. Precipitation manipulation and modeling experiments should combine with changes in other climate and soil factors to better predict the response of plant productivity under future climate. Copyright © 2017 Elsevier B.V. All rights reserved.

19. Reconciling the Log-Linear and Non-Log-Linear Nature of the TSH-Free T4 Relationship: Intra-Individual Analysis of a Large Population.

Rothacker, Karen M; Brown, Suzanne J; Hadlow, Narelle C; Wardrop, Robert; Walsh, John P

2016-03-01

The TSH-T4 relationship was thought to be inverse log-linear, but recent cross-sectional studies report a complex, nonlinear relationship; large, intra-individual studies are lacking. Our objective was to analyze the TSH-free T4 relationship within individuals. We analyzed data from 13 379 patients, each with six or more TSH/free T4 measurements and at least a 5-fold difference between individual median TSH and minimum or maximum TSH. Linear and nonlinear regression models of log TSH on free T4 were fitted to data from individuals and goodness of fit compared by likelihood ratio testing. Comparing all models, the linear model achieved best fit in 31% of individuals, followed by quartic (27%), cubic (15%), null (12%), and quadratic (11%) models. After eliminating least favored models (with individuals reassigned to best fitting, available models), the linear model fit best in 42% of participants, quartic in 43%, and null model in 15%. As the number of observations per individual increased, so did the proportion of individuals in whom the linear model achieved best fit, to 66% in those with more than 20 observations. When linear models were applied to all individuals and averaged according to individual median free T4 values, variations in slope and intercept indicated a nonlinear log TSH-free T4 relationship across the population. The log TSH-free T4 relationship appears linear in some individuals and nonlinear in others, but is predominantly linear in those with the largest number of observations. A log-linear relationship within individuals can be reconciled with a non-log-linear relationship in a population.

20. The Non-Linear Relationship Between Fiscal Deficits And Inflation: Evidence From Africa

Abu Nurudeen

2015-12-01

Full Text Available Although, there is abundant research on the fiscal deficit-inflation relationship, little has been done to investigate the non-linear association between them, particularly in Africa. This study employs fixed-effects and GMM estimators to examine the non-linear relationship between deficits and inflation from 1999 to 2011 in 51 African economies, which are further grouped into high-inflation/low-income countries and moderate-inflation/middle-income countries. The results indicate that the deficit-inflation relationship is non-linear for the whole sample and sub-groups. For the whole sample, a percentage point increase in deficit results in a 0.25 percentage point increase in inflation rate, while the relationship becomes quantitatively greater once deficits reach 23% of GDP. The subsamples report different relationships. Although our results cannot be used as the base for generalization, we identify importance of grouping African countries according to their levels of inflation and/or income, rather than treating them as a homogeneous entity.

1. Existence of 2m-1 Positive Solutions for Sturm-Liouville Boundary Value Problems with Linear Functional Boundary Conditions on the Half-Line

Yanmei Sun

2012-01-01

Full Text Available By using the Leggett-Williams fixed theorem, we establish the existence of multiple positive solutions for second-order nonhomogeneous Sturm-Liouville boundary value problems with linear functional boundary conditions. One explicit example with singularity is presented to demonstrate the application of our main results.

2. The Relationship between Economic Growth and Money Laundering – a Linear Regression Model

Daniel Rece

2009-09-01

Full Text Available This study provides an overview of the relationship between economic growth and money laundering modeled by a least squares function. The report analyzes statistically data collected from USA, Russia, Romania and other eleven European countries, rendering a linear regression model. The study illustrates that 23.7% of the total variance in the regressand (level of money laundering is “explained” by the linear regression model. In our opinion, this model will provide critical auxiliary judgment and decision support for anti-money laundering service systems.

3. Transmission of linear regression patterns between time series: from relationship in time series to complex networks.

Gao, Xiangyun; An, Haizhong; Fang, Wei; Huang, Xuan; Li, Huajiao; Zhong, Weiqiong; Ding, Yinghui

2014-07-01

The linear regression parameters between two time series can be different under different lengths of observation period. If we study the whole period by the sliding window of a short period, the change of the linear regression parameters is a process of dynamic transmission over time. We tackle fundamental research that presents a simple and efficient computational scheme: a linear regression patterns transmission algorithm, which transforms linear regression patterns into directed and weighted networks. The linear regression patterns (nodes) are defined by the combination of intervals of the linear regression parameters and the results of the significance testing under different sizes of the sliding window. The transmissions between adjacent patterns are defined as edges, and the weights of the edges are the frequency of the transmissions. The major patterns, the distance, and the medium in the process of the transmission can be captured. The statistical results of weighted out-degree and betweenness centrality are mapped on timelines, which shows the features of the distribution of the results. Many measurements in different areas that involve two related time series variables could take advantage of this algorithm to characterize the dynamic relationships between the time series from a new perspective.

4. Linear proportional relationship between N(OH) and N(CH) in the diffuse interstellar medium

Hong, Seung Yeong; Kwak, Kyujin

2018-04-01

It has been known that there is a linearly proportional relationship between the column densities of CH and OH measured toward bright UV-emitting stars, although there are four outliers in this relationship among the total 24 measured targets. By using the Simbad database, we investigate reasonable configurations of diffuse interstellar medium (ISM) which could explain the observed relationship. We first identify the locations of 24 targets on the celestial sphere getting the distances to them and then count the number of molecular clouds, nebulae, and peculiar stars toward the targets which could contribute to the production of OH and CH. We present the results of our search by testing three hypothetical configurations of diffuse ISM which may explain the observed relationship.

5. Positivity and job burnout in emergency personnel: examining linear and curvilinear relationship

Basińska Beata Aleksandra

2017-06-01

Full Text Available The aim of this study was to examine whether the relationship between the ratio of job-related positive to negative emotions (positivity ratio and job burnout is best described as linear or curvilinear. Participants were 89 police officers (12% women and 86 firefighters. The positivity ratio was evaluated using the Job-related Affective Wellbeing Scale (Van Katwyk, Fox, Spector, & Kelloway, 2000. Exhaustion and disengagement, two components of job burnout, were measured using the Oldenburg Burnout Inventory (Demerouti, Mostert, & Bakker, 2010. The results of regression analysis revealed that curvilinear relationships between the positivity ratio and two components of job burnout appeared to better fit the data than linear relationships. The relationship between the positivity ratio and exhaustion was curvilinear with a curve point at around 2.1. A similar curvilinear relationship, but with a lower curve point, i.e., around 1.8, was observed for disengagement. It seems that beyond certain values there may be hidden costs of maintaining positive emotions at work. Also, the unequal curve points for subscales suggest that different dimensions of work-related functioning are variously prone to such costs.

6. Water pollution and income relationships: A seemingly unrelated partially linear analysis

Pandit, Mahesh; Paudel, Krishna P.

2016-10-01

We used a seemingly unrelated partially linear model (SUPLM) to address a potential correlation between pollutants (nitrogen, phosphorous, dissolved oxygen and mercury) in an environmental Kuznets curve study. Simulation studies show that the SUPLM performs well to address potential correlation among pollutants. We find that the relationship between income and pollution follows an inverted U-shaped curve for nitrogen and dissolved oxygen and a cubic shaped curve for mercury. Model specification tests suggest that a SUPLM is better specified compared to a parametric model to study the income-pollution relationship. Results suggest a need to continually assess policy effectiveness of pollution reduction as income increases.

7. Threat Appeals: The Fear-Persuasion Relationship is Linear and Curvilinear.

Dillard, James Price; Li, Ruobing; Huang, Yan

2017-11-01

Drive theory may be seen as the first scientific theory of health and risk communication. However, its prediction of a curvilinear association between fear and persuasion is generally held to be incorrect. A close rereading of Hovland et al. reveals that within- and between-persons processes were conflated. Using a message that advocated obtaining a screening for colonoscopy, this study (N = 259) tested both forms of the inverted-U hypothesis. In the between-persons data, analyses revealed a linear effect that was consistent with earlier investigations. However, the data showed an inverted-U relationship in within-persons data. Hence, the relationship between fear and persuasion is linear or curvilinear depending on the level of analysis.

8. A Non-linear "Inflation-Relative Prices Variability" Relationship: Evidence from Latin America

Mª Ángeles Caraballo Pou; Carlos Dabús; Diego Caramuta

2006-01-01

This paper presents evidence on a non-linear "inflation-relative prices variability" relationship in three Latin American countries with very high inflation experiences: Argentina, Brazil and Peru. More precisely, and in contrast to results found in previous literature for similar countries, we find a non-concave relation at higher inflation regimes, i.e. when inflation rate surpasses certain threshold. This non-concavity is mainly explained by the unexpected component of inflation, which sug...

9. Tests of the linearity assumption in the dose-effect relationship for radiation-induced cancer

Cohen, A.F.; Cohen, B.L.

1978-01-01

The validity of the BEIR linear extrapolation to low doses of the dose-effect relationship for radiation induced cancer is tested by use of natural radiation making use of selectivity on type of cancer, sex, age group, geographic area, and time period. For lung cancer, a linear interpolation between zero dose-zero effect and the data from radon-induced cancers in miners over-estimates the total number of observed lung cancers in many countries in the early years of this century; the discrepancy is substantially increased if the 30-44 year age range and/or if only females are considered, and by the fact that many other causes of lung cancer are shown to have been important at that time. The degree to which changes of diagnostic efficiency with time can influence the analysis is considered at some length. It is concluded that the linear relationship substantially over-estimates effects of low radiation doses. A similar analysis is applied to leukemia induced by natural radiation, applying selectivity by age, sex, natural background level, and date, and considering other causes. It is concluded that effects substantially larger than those obtained from linear extrapolation are excluded. The use of the selectivities mentioned above is justified by the fact that the incidence of cancer or leukemia is an upper limit on the rate at which it is caused by radiation effects; in determining upper limits it is justifiable to select situations which minimize it. (author)

10. 40 CFR 63.481 - Compliance dates and relationship of this subpart to existing applicable rules.

2010-07-01

... changes to the existing barrier fluid system; or (iv) The compressor will be modified to permit connecting the compressor to a fuel gas system or closed vent system, or be modified so that emissions from the... are required to connect to a closed-vent or recovery system. (5) Compliance with the surge control...

11. 40 CFR 63.1422 - Compliance dates and relationship of this rule to existing applicable rules.

2010-07-01

... existing barrier fluid system. (iv) The compressor shall be modified to permit connecting the compressor to a closed vent system. (2) Compliance with the compressor provisions of § 63.164 shall occur no later... closed-vent system. (5) Compliance with the surge control vessel and bottoms receiver provisions of § 63...

12. 28 CFR 522.13 - Relationship between existing civil contempt commitment orders and new criminal sentences imposed...

2010-07-01

... contempt commitment orders and new criminal sentences imposed under the U.S. or D.C. Code. 522.13 Section..., CLASSIFICATION, AND TRANSFER ADMISSION TO INSTITUTION Civil Contempt of Court Commitments § 522.13 Relationship between existing civil contempt commitment orders and new criminal sentences imposed under the U.S. or D.C...

13. Tests of the linearity assumption in the dose-effect relationship for radiation-induced cancer

Cohen, A.F.; Cohen, B.L.

1980-01-01

The validity of the BEIR linear extrapolation to low doses of the dose-effect relationship for radiation induced cancer is tested by use of natural radiation making use of selectivity on type of cancer, smoking habits, sex, age group, geographic area and/or time period. For lung cancer, a linear interpolation between zero dose-zero effect and the data from radon-induced cancers in miners implies that the majority of all lung cancers among non-smokers are due to radon; since lung cancers in miners are mostly small-cell undifferentiated (SCU), a rather rare type in general, linearity over predicts the frequency of SCU lung cancers among non smokers by a factor of 10, and among non-smoking females age 25-44 by a factor of 24. Similarly, linearity predicts that the majority of all lung cancers early in this century were due to radon even after due consideration is given to cases missed by poor diagnostic efficiency (this matter is considered in some detail). For the 30-40 age range, linearity over predicts the total lung cancer rate at that time by a factor of 3-6; for SCU lung cancer, the over-prediction is by at least a factor of 10. Other causes of lung cancer are considered which further enhance the degree to which the linearity assumption over-estimates the effects of low level radiation. A similar analysis is applied to leukemia induced by natural radiation. It is concluded that the upper limit for this is not higher than estimates from the linearity hypothesis. (author)

14. A Simple Piece of Apparatus to Aid the Understanding of the Relationship between Angular Velocity and Linear Velocity

Unsal, Yasin

2011-01-01

One of the subjects that is confusing and difficult for students to fully comprehend is the concept of angular velocity and linear velocity. It is the relationship between linear and angular velocity that students find difficult; most students understand linear motion in isolation. In this article, we detail the design, construction and…

15. Macro economy, stock market and oil prices. Do meaningful relationships exist among their cyclical fluctuations?

Filis, George

2010-01-01

This paper examines the relationship among consumer price index, industrial production, stock market and oil prices in Greece. Initially we use a unified statistical framework (cointegration and VECM) to study the data in levels. We then employ a multivariate VAR model to examine the relationship among the cyclical components of our series. The period of the study is from 1996:1 to 2008:6. Findings suggest that oil prices and the stock market exercise a positive effect on the Greek CPI, in the long run. Cyclical components analysis suggests that oil prices exercise significant negative influence to the stock market. In addition, oil prices are negatively influencing CPI, at a significant level. However, we find no effect of oil prices on industrial production and CPI. Finally, no relationship can be documented between the industrial production and stock market for the Greek market. The findings of this study are of particular interest and importance to policy makers, financial managers, financial analysts and investors dealing with the Greek economy and the Greek stock market. (author)

16. On the linearity of the dose-effect relationship of DNA double strand breaks

Chadwick, K.H.; Leenhouts, H.P.

1994-01-01

Most radiation biologists believe that DNA double-strand breaks are induced linearly with radiation dose for all types of radiation. Since 1985, with the advent of elution and gel electrophoresis techniques which permit the measurement of DNA double-strand breaks induced in mammalian cells at doses having radiobiological relevance, the true nature of the dose-effect relationship has been brought into some doubt. Many investigators measured curvilinear dose-effect relationships and a few found good correlations between the induction of the DNA double-strand breaks and cell survival. We approach the problem pragmatically by assuming that the induction of DNA double-strand breaks by 125 I Auger electron emitters incorporated into the DNA of the cells is a linear function of the number of 125 I decays, and by comparing the dose-effect relationship for sparsely ionizing radiation against this standard. The conclusion drawn that the curvilinear dose-effect relationships and the correlations with survival are real. (Author)

17. EXISTS A RELATIONSHIP BETWEEN STRATEGIC HUMAN RESOURCES MANAGEMENT, INNOVATION AND COMPETITIVE ADVANTAGE?

Anca-Ioana MUNTEANU

2015-01-01

This paper is purely theoretical, having as starting points both existing information in the literature and their correlations. The text does not have a generalized, but represent personal opinions and conclusions. Critically analyzing the definitions given in the literature the term "strategic human resource management ", we found that most of them referred to the involvement he has it in obtaining competitive advantage of an organization. Also, starting from the study of different approache...

18. EXISTS A RELATIONSHIP BETWEEN STRATEGIC HUMAN RESOURCES MANAGEMENT, INNOVATION AND COMPETITIVE ADVANTAGE?

ANCA-IOANA MUNTEANU

2015-02-01

Full Text Available This paper is purely theoretical, having as starting points both existing information in the literature and their correlations. The text does not have a generalized, but represent personal opinions and conclusions. Critically analyzing the definitions given in the literature the term "strategic human resource management ", we found that most of them referred to the involvement he has it in obtaining competitive advantage of an organization. Also, starting from the study of different approaches to strategic management of human resources, we can see that besides the role that obtain competitive advantage, it supports innovative activity of a company. So we can talk about a link between strategic management of human resources, innovation and achieving competitive advantage. By presenting how strategic human resource management can be implemented in an organization, its high performance practices for human resources, it demonstrates that they support employee creativity through free expression of ideas, involvement in decision making, resulting in the way to innovation and thus to obtain competitive advantage. This work, theoretical, was completed by a presentation that show the interdependencies that exist between the three think elements: strategic human resources management, innovation, competitive advantage.

19. The relationship between crude oil spot and futures prices: Cointegration, linear and nonlinear causality

Bekiros, Stelios D.; Diks, Cees G.H.

2008-01-01

The present study investigates the linear and nonlinear causal linkages between daily spot and futures prices for maturities of one, two, three and four months of West Texas Intermediate (WTI) crude oil. The data cover two periods October 1991-October 1999 and November 1999-October 2007, with the latter being significantly more turbulent. Apart from the conventional linear Granger test we apply a new nonparametric test for nonlinear causality by Diks and Panchenko after controlling for cointegration. In addition to the traditional pairwise analysis, we test for causality while correcting for the effects of the other variables. To check if any of the observed causality is strictly nonlinear in nature, we also examine the nonlinear causal relationships of VECM filtered residuals. Finally, we investigate the hypothesis of nonlinear non-causality after controlling for conditional heteroskedasticity in the data using a GARCH-BEKK model. Whilst the linear causal relationships disappear after VECM cointegration filtering, nonlinear causal linkages in some cases persist even after GARCH filtering in both periods. This indicates that spot and futures returns may exhibit asymmetric GARCH effects and/or statistically significant higher order conditional moments. Moreover, the results imply that if nonlinear effects are accounted for, neither market leads or lags the other consistently, videlicet the pattern of leads and lags changes over time. (author)

20. The Relationships of Subparallel Synthetic Faults and Pre-existing Structures in the Central Malawi Rift

Johnson, S.; Mendez, K.; Beresh, S. C. M.; Mynatt, W. G.; Elifritz, E. A.; Laó-Dávila, D. A.; Atekwana, E. A.; Abdelsalam, M. G.; Chindandali, P. R. N.; Chisenga, C.; Gondwe, S.; Mkumbura, M.; Kalaguluka, D.; Kalindekafe, L.; Salima, J.

2017-12-01

The objective of our research is to explore the evolution of synthetic fault systems in continental rifts. It has been suggested that during the rifting process border faults may become locked and strain is then accommodated within the hanging wall. The Malawi Rift provides an opportunity to study the evolution of these faults within a young (8 Ma), active and magma-poor continental rift. Two faults in central Malawi may show the transference of strain into the hanging wall. These faults are the older Chirobwe-Ntcheu with a length of 115 km and a scarp height of 300-1000 m and the younger Bilila-Mtakataka with a length of 130 km and a scarp height of 4-320 m. We used high-resolution aeromagnetic data and 30m resolution Shuttle Radar Topography Mission (SRTM) digital elevation models (DEM) to provide a 3D spatial characterization of the fault system. Additionally 10cm resolution DEMs were created using unmanned aerial system (UAS) derived aerial photography and Structure from Motion to document the regional Precambrian foliation and joint patterns. Moreover, displacement profiles where extracted from the SRTM-DEM data to compare the segmentation and linkage of the outer and inner faults. Our preliminary results show that the strike of each fault is approximately NW-SE which follows the strike of the Precambrian fabric. The magnetic fabric has a strike of NW-SE in the south changing to NE-SW in the north suggesting that the faults are controlled in part by an inherited Precambrian fabric. The displacement profile of the inner Bilila-Mtakataka fault is asymmetric and displays five fault segments supporting the interpretation that this is a relatively young fault. The expected results of this study are information about segmentation and displacement of each fault and their relationship to one another. The results from the aeromagnetic data utilizing Source Parameter Imaging to produce an approximate depth to basement which will support the displacement profiles derived

1. Linearization Method and Linear Complexity

Tanaka, Hidema

We focus on the relationship between the linearization method and linear complexity and show that the linearization method is another effective technique for calculating linear complexity. We analyze its effectiveness by comparing with the logic circuit method. We compare the relevant conditions and necessary computational cost with those of the Berlekamp-Massey algorithm and the Games-Chan algorithm. The significant property of a linearization method is that it needs no output sequence from a pseudo-random number generator (PRNG) because it calculates linear complexity using the algebraic expression of its algorithm. When a PRNG has n [bit] stages (registers or internal states), the necessary computational cost is smaller than O(2n). On the other hand, the Berlekamp-Massey algorithm needs O(N2) where N(≅2n) denotes period. Since existing methods calculate using the output sequence, an initial value of PRNG influences a resultant value of linear complexity. Therefore, a linear complexity is generally given as an estimate value. On the other hand, a linearization method calculates from an algorithm of PRNG, it can determine the lower bound of linear complexity.

2. Linear solvation energy relationships: "rule of thumb" for estimation of variable values

Hickey, James P.; Passino-Reader, Dora R.

1991-01-01

For the linear solvation energy relationship (LSER), values are listed for each of the variables (Vi/100, π*, &betam, αm) for fundamental organic structures and functional groups. We give the guidelines to estimate LSER variable values quickly for a vast array of possible organic compounds such as those found in the environment. The difficulty in generating these variables has greatly discouraged the application of this quantitative structure-activity relationship (QSAR) method. This paper present the first compilation of molecular functional group values together with a utilitarian set of the LSER variable estimation rules. The availability of these variable values and rules should facilitate widespread application of LSER for hazard evaluation of environmental contaminants.

3. Mining routinely collected acute data to reveal non-linear relationships between nurse staffing levels and outcomes.

Leary, Alison; Cook, Rob; Jones, Sarahjane; Smith, Judith; Gough, Malcolm; Maxwell, Elaine; Punshon, Geoffrey; Radford, Mark

2016-12-16

Nursing is a safety critical activity but not easily quantified. This makes the building of predictive staffing models a challenge. The aim of this study was to determine if relationships between registered and non-registered nurse staffing levels and clinical outcomes could be discovered through the mining of routinely collected clinical data. The secondary aim was to examine the feasibility and develop the use of 'big data' techniques commonly used in industry for this area of healthcare and examine future uses. The data were obtained from 1 large acute National Health Service hospital trust in England. Routinely collected physiological, signs and symptom data from a clinical database were extracted, imported and mined alongside a bespoke staffing and outcomes database using Mathmatica V.10. The physiological data consisted of 120 million patient entries over 6 years, the bespoke database consisted of 9 years of daily data on staffing levels and safety factors such as falls. To discover patterns in these data or non-linear relationships that would contribute to modelling. To examine feasibility of this technique in this field. After mining, 40 correlations (pdata (such as the presence or absence of nausea) and staffing factors. Several inter-related factors demonstrated step changes where registered nurse availability appeared to relate to physiological parameters or outcomes such as falls and the management of symptoms. Data extraction proved challenging as some commercial databases were not built for extraction of the massive data sets they contain. The relationship between staffing and outcomes appears to exist. It appears to be non-linear but calculable and a data-driven model appears possible. These findings could be used to build an initial mathematical model for acute staffing which could be further tested. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

4. Examining Vegetation of Built Landscapes and Their Relationship to Existing Ecosystems

Margaret Livingston

2004-06-01

Full Text Available An understanding of the various influences of urbanisation on plant communities is critical for planning a sustainable future for the planet. For example, landscape practices and sense of place driven by aesthetic influences often dominate in the design of built landscapes, resulting in strikingly different vegetation communities from that of the surrounding communities. Furthermore, these built landscapes in metropolitan areas often markedly influence an inhabitant's impressions of a region's biotic foundation and sense of place. Inhabitants may not consider or understand the ecological impacts of practices that are typically dominated by contemporary cultural aesthetics. Do these cultural aesthetic drivers result in relatively similar landscapes in terms of appearance, regardless of region? The purpose of this study was to document general trends in landscape structure and composition from two distinct, different regions. Specifically, we addressed the questions: how do these built landscapes deviate from their surrounding natural communities and are these built landscapes from the two regions similar in structure and composition? This paper characterised landscape vegetation patterns of typical residential areas in two cities with relatively diverse climatic regions, Tucson, Arizona and Atlanta, Georgia. Comparisons were done on data for plant diversity, density, life form (tree, shrub, groundcover, and vines and species origin (native versus non-native from sites within typical residential subdivisions throughout the two cities. Results were compared with the composition of local typology in order to determine what differences and similarities existed in relation to native biotic communities. In both cities, residential landscapes converged on savannah-type landscapes, emphasising scattered overstory and minimal understory that were more compositionally diverse than the native biotic communities because of the introduction of non

5. Linear free energy relationship applied to trivalent cations with lanthanum and actinium oxide and hydroxide structure

Ragavan, Anpalaki J.

2006-01-01

Linear free energy relationships for trivalent cations with crystalline M 2 O 3 and, M(OH) 3 phases of lanthanides and actinides were developed from known thermodynamic properties of the aqueous trivalent cations, modifying the Sverjensky and Molling equation. The linear free energy relationship for trivalent cations is as ΔG f,MvX 0 =a MvX ΔG n,M 3+ 0 +b MvX +β MvX r M 3+ , where the coefficients a MvX , b MvX , and β MvX characterize a particular structural family of MvX, r M 3+ is the ionic radius of M 3+ cation, ΔG f,MvX 0 is the standard Gibbs free energy of formation of MvX and ΔG n,M 3+ 0 is the standard non-solvation free energy of the cation. The coefficients for the oxide family are: a MvX =0.2705, b MvX =-1984.75 (kJ/mol), and β MvX =197.24 (kJ/molnm). The coefficients for the hydroxide family are: a MvX =0.1587, b MvX =-1474.09 (kJ/mol), and β MvX =791.70 (kJ/molnm).

6. The Relationship between Residential Electricity Consumption and Income: A Piecewise Linear Model with Panel Data

Yanan Liu

2016-10-01

Full Text Available There are many uncertainties and risks in residential electricity consumption associated with economic development. Knowledge of the relationship between residential electricity consumption and its key determinant—income—is important to the sustainable development of the electric power industry. Using panel data from 30 provinces for the 1995–2012 period, this study investigates how residential electricity consumption changes as incomes increase in China. Previous studies typically used linear or quadratic double-logarithmic models imposing ex ante restrictions on the indistinct relationship between residential electricity consumption and income. Contrary to those models, we employed a reduced piecewise linear model that is self-adaptive and highly flexible and circumvents the problem of “prior restrictions”. Robust tests of different segment specifications and regression methods are performed to ensure the validity of the research. The results provide strong evidence that the income elasticity was approximately one, and it remained stable throughout the estimation period. The income threshold at which residential electricity consumption automatically remains stable or slows has not been reached. To ensure the sustainable development of the electric power industry, introducing higher energy efficiency standards for electrical appliances and improving income levels are vital. Government should also emphasize electricity conservation in the industrial sector rather than in residential sector.

7. A linear solvation energy relationship model of organic chemical partitioning to dissolved organic carbon.

Kipka, Undine; Di Toro, Dominic M

2011-09-01

Predicting the association of contaminants with both particulate and dissolved organic matter is critical in determining the fate and bioavailability of chemicals in environmental risk assessment. To date, the association of a contaminant to particulate organic matter is considered in many multimedia transport models, but the effect of dissolved organic matter is typically ignored due to a lack of either reliable models or experimental data. The partition coefficient to dissolved organic carbon (K(DOC)) may be used to estimate the fraction of a contaminant that is associated with dissolved organic matter. Models relating K(DOC) to the octanol-water partition coefficient (K(OW)) have not been successful for many types of dissolved organic carbon in the environment. Instead, linear solvation energy relationships are proposed to model the association of chemicals with dissolved organic matter. However, more chemically diverse K(DOC) data are needed to produce a more robust model. For humic acid dissolved organic carbon, the linear solvation energy relationship predicts log K(DOC) with a root mean square error of 0.43. Copyright © 2011 SETAC.

8. Non-Linear Relationship between Economic Growth and CO₂ Emissions in China: An Empirical Study Based on Panel Smooth Transition Regression Models.

Wang, Zheng-Xin; Hao, Peng; Yao, Pei-Yi

2017-12-13

The non-linear relationship between provincial economic growth and carbon emissions is investigated by using panel smooth transition regression (PSTR) models. The research indicates that, on the condition of separately taking Gross Domestic Product per capita (GDPpc), energy structure (Es), and urbanisation level (Ul) as transition variables, three models all reject the null hypothesis of a linear relationship, i.e., a non-linear relationship exists. The results show that the three models all contain only one transition function but different numbers of location parameters. The model taking GDPpc as the transition variable has two location parameters, while the other two models separately considering Es and Ul as the transition variables both contain one location parameter. The three models applied in the study all favourably describe the non-linear relationship between economic growth and CO₂ emissions in China. It also can be seen that the conversion rate of the influence of Ul on per capita CO₂ emissions is significantly higher than those of GDPpc and Es on per capita CO₂ emissions.

9. On the Relationship Between Confidence Sets and Exchangeable Weights in Multiple Linear Regression.

Pek, Jolynn; Chalmers, R Philip; Monette, Georges

2016-01-01

When statistical models are employed to provide a parsimonious description of empirical relationships, the extent to which strong conclusions can be drawn rests on quantifying the uncertainty in parameter estimates. In multiple linear regression (MLR), regression weights carry two kinds of uncertainty represented by confidence sets (CSs) and exchangeable weights (EWs). Confidence sets quantify uncertainty in estimation whereas the set of EWs quantify uncertainty in the substantive interpretation of regression weights. As CSs and EWs share certain commonalities, we clarify the relationship between these two kinds of uncertainty about regression weights. We introduce a general framework describing how CSs and the set of EWs for regression weights are estimated from the likelihood-based and Wald-type approach, and establish the analytical relationship between CSs and sets of EWs. With empirical examples on posttraumatic growth of caregivers (Cadell et al., 2014; Schneider, Steele, Cadell & Hemsworth, 2011) and on graduate grade point average (Kuncel, Hezlett & Ones, 2001), we illustrate the usefulness of CSs and EWs for drawing strong scientific conclusions. We discuss the importance of considering both CSs and EWs as part of the scientific process, and provide an Online Appendix with R code for estimating Wald-type CSs and EWs for k regression weights.

10. Linear relationship between peak and season-long abundances in insects.

Ksenia S Onufrieva

Full Text Available An accurate quantitative relationship between key characteristics of an insect population, such as season-long and peak abundances, can be very useful in pest management programs. To the best of our knowledge, no such relationship has yet been established. Here we establish a predictive linear relationship between insect catch Mpw during the week of peak abundance, the length of seasonal flight period, F (number of weeks and season-long cumulative catch (abundance A = 0.41MpwF. The derivation of the equation is based on several general assumptions and does not involve fitting to experimental data, which implies generality of the result. A quantitative criterion for the validity of the model is presented. The equation was tested using extensive data collected on captures of male gypsy moths Lymantria dispar (L. (Lepidoptera: Erebidae in pheromone-baited traps during 15 years. The model was also tested using trap catch data for two species of mosquitoes, Culex pipiens (L. (Diptera: Culicidae and Aedes albopictus (Skuse (Diptera: Culicidae, in Gravid and BG-sentinel mosquito traps, respectively. The simple, parameter-free equation approximates experimental data points with relative error of 13% and R2 = 0.997, across all of the species tested. For gypsy moth, we also related season-long and weekly trap catches to the daily trap catches during peak flight. We describe several usage scenarios, in which the derived relationships are employed to help link results of small-scale field studies to the operational pest management programs.

11. The relationships among iron supplement use, Hb concentration and linear growth in young children: Ethiopian Demographic and Health Survey.

2017-11-01

Growth faltering and anaemia remain unacceptably high among infants and young children in Ethiopia. In this study, we investigated the relationships among Fe supplement use (ISU), Hb concentration and linear growth, hypothesising positive relationships between ISU and Hb, ISU and linear growth and Hb and linear growth. We used a nationally representative data of 2400 children aged 6-24 months from the Ethiopian Demographic and Health Survey (EDHS) 2011, conducted following a stratified, two-stage cluster sampling. We examined the links by Pearson's correlation, bivariate and multivariate linear regression analyses and reported adjusted estimates. We found that ISU was not significantly associated with either Hb (β=1·09; 95 % CI -2·73, 5·01, P=0·567) or linear growth (β=0·07; 95 % CI -0·06, 0·21, P=0·217). We found a positive, however, weak, correlation between Hb and linear growth (r 0·09; 95 % CI 0·06, 0·11, PHb predicted linear growth independent of a variety dietary and non-dietary factors (β=0·08; 95 % CI 0·04, 0·11, PHb; age, birth type, size at birth, sex, breast-feeding duration, dietary diversity and deworming were independently associated with linear growth, indicating that Hb and linear growth are multifactorial with both nutritional and non-nutritional factors implicated. Further studies, with better design and exposure assessment, are warranted on the relation of ISU with Hb or linear growth.

12. Substance use disorder counselors' job performance and turnover after 1 year: linear or curvilinear relationship?

Laschober, Tanja C; de Tormes Eby, Lillian Turner

2013-07-01

The main goals of the current study were to investigate whether there are linear or curvilinear relationships between substance use disorder counselors' job performance and actual turnover after 1 year utilizing four indicators of job performance and three turnover statuses (voluntary, involuntary, and no turnover as the reference group). Using longitudinal data from 440 matched counselor-clinical supervisor dyads, results indicate that overall, counselors with lower job performance are more likely to turn over voluntarily and involuntarily than not to turn over. Further, one of the job performance measures shows a significant curvilinear effect. We conclude that the negative consequences often assumed to be "caused" by counselor turnover may be overstated because those who leave both voluntarily and involuntarily demonstrate generally lower performance than those who remain employed at their treatment program.

13. Solvent effects in ionic liquids: empirical linear energy-density relationships.

Cerda-Monje, A; Aizman, A; Tapia, R A; Chiappe, C; Contreras, R

2012-07-28

Multiparameter linear energy-density relationships to model solvent effects in room temperature ionic liquids (RTILs) are introduced and tested. The model incorporates two solvent dependent and two specific solute-solvent parameters represented by a set of electronic indexes derived from the conceptual density functional theory. The specific solute-solvent interactions are described in terms of the electronic chemical potential for proton migration between the anion or cation and the transition state structure of a specific reaction. These indexes provide a quantitative estimation of the hydrogen bond (HB) acceptor basicity and the hydrogen bond donor acidity of the ionic solvent, respectively. A sound quantitative scale of HB strength is thereby obtained. The solvent dependent contributions are described by the global electrophilicity of the cation and nucleophilicity of the anion forming the ionic liquid. The model is illustrated for the kinetics of cycloaddition of cyclopentadiene towards acrolein. In general, cation HB acidity outweighs the remaining parameters for this reaction.

14. Substance Use Disorder Counselors’ Job Performance and Turnover after 1 Year: Linear or Curvilinear Relationship?1

Laschober, Tanja C.; de Tormes Eby, Lillian Turner

2013-01-01

The main goals of the current study were to investigate whether there are linear or curvilinear relationships between substance use disorder counselors’ job performance and actual turnover after 1 year utilizing four indicators of job performance and three turnover statuses (voluntary, involuntary, and no turnover as the reference group). Using longitudinal data from 440 matched counselor-clinical supervisor dyads, results indicate that overall, counselors with lower job performance are more likely to turn over voluntarily and involuntarily than not to turn over. Further, one of the job performance measures shows a significant curvilinear effect. We conclude that the negative consequences often assumed to be “caused” by counselor turnover may be overstated because those who leave both voluntarily and involuntarily demonstrate generally lower performance than those who remain employed at their treatment program. PMID:22527711

15. Lead-lag relationships between stock and market risk within linear response theory

Borysov, Stanislav; Balatsky, Alexander

2015-03-01

We study historical correlations and lead-lag relationships between individual stock risks (standard deviation of daily stock returns) and market risk (standard deviation of daily returns of a market-representative portfolio) in the US stock market. We consider the cross-correlation functions averaged over stocks, using historical stock prices from the Standard & Poor's 500 index for 1994-2013. The observed historical dynamics suggests that the dependence between the risks was almost linear during the US stock market downturn of 2002 and after the US housing bubble in 2007, remaining at that level until 2013. Moreover, the averaged cross-correlation function often had an asymmetric shape with respect to zero lag in the periods of high correlation. We develop the analysis by the application of the linear response formalism to study underlying causal relations. The calculated response functions suggest the presence of characteristic regimes near financial crashes, when individual stock risks affect market risk and vice versa. This work was supported by VR 621-2012-2983.

16. Non-Linear Dose Response Relationships in Biology, Toxicology, and Medicine (June 8-10, 2004). Final Report

Calabrese, Edward J.

2004-01-01

The conference attracts approximately 500 scientists researching in the area of non-linear low dose effects. These scientists represent a wide range of biological/medical fields and technical disciplines. Observations that biphasic dose responses are frequently reported in each of these areas but that the recognition of similar dose response relationships across disciplines is very rarely appreciated and exploited. By bringing scientist of such diverse backgrounds together who are working on the common area of non-linear dose response relationships this will enhance our understanding of the occurrence, origin, mechanism, significance and practical applications of such dose response relationships

17. A biological basis for the linear non-threshold dose-response relationship for low-level carcinogen exposure

Albert, R.E.

1981-01-01

This chapter examines low-level dose-response relationships in terms of the two-stage mouse tumorigenesis model. Analyzes the feasibility of the linear non-threshold dose-response model which was first adopted for use in the assessment of cancer risks from ionizing radiation and more recently from chemical carcinogens. Finds that both the interaction of B(a)P with epidermal DNA of the mouse skin and the dose-response relationship for the initiation stage of mouse skin tumorigenesis showed a linear non-threshold dose-response relationship. Concludes that low level exposure to environmental carcinogens has a linear non-threshold dose-response relationship with the carcinogen acting as an initiator and the promoting action being supplied by the factors that are responsible for the background cancer rate in the target tissue

18. Recent results on the linearity of the dose-response relationship for radiation-induced mutations in human cells by low dose levels

Traut, H.

1987-01-01

Five studies made by various authors in the last years are discussed, which are significant in that the response of human cells to low-dose irradiation is determined directly and not by extrapolation, and which also provide information on the mutagenic effects of low radiation doses. The results of these studies do not indicate any other than a linear response for induction of mutations by low-dose irradiation, nor are there any reasons observable for assuming the existence of a threshold dose. It is very likely therefore that cancer initiation at the low dose level also is characterized by a linear relationship. Although threshold dose levels cannot generally be excluded, and maybe are only too low to be detected by experiment, there is no plausible biophysical argument for assuming the existence of such microdose threshold. (orig./MG) [de

19. Comparing Machine Learning Classifiers and Linear/Logistic Regression to Explore the Relationship between Hand Dimensions and Demographic Characteristics.

Miguel-Hurtado, Oscar; Guest, Richard; Stevenage, Sarah V; Neil, Greg J; Black, Sue

2016-01-01

Understanding the relationship between physiological measurements from human subjects and their demographic data is important within both the biometric and forensic domains. In this paper we explore the relationship between measurements of the human hand and a range of demographic features. We assess the ability of linear regression and machine learning classifiers to predict demographics from hand features, thereby providing evidence on both the strength of relationship and the key features underpinning this relationship. Our results show that we are able to predict sex, height, weight and foot size accurately within various data-range bin sizes, with machine learning classification algorithms out-performing linear regression in most situations. In addition, we identify the features used to provide these relationships applicable across multiple applications.

20. On the existence of a threshold in the dose-response relationship from the epidemiological data of atomic bomb survivors

Matsuura, Tatsuo; Sugahara, Tsutomu

2002-01-01

Whether or not there is a threshold dose in the dose-response relationship for cancer incidence due to radiation is one of the most important but controversial issues in radiation protection and nuclear policy making. The epidemiological studies on the Life Span Study (LSS) group of atomic bomb survivors in Hiroshima and Nagasaki, conducted by Radiation Effects Research Foundation (RERF) have been regarded to be most authentic, and they keep the view that there is no evidence to deny the linear non-threshold (LNT) hypotheses. The authors have claimed the necessity of reassessment of exposure doses of survivors, by considering the contribution of chronic dose, which comes from fall-out, induced radioactivity, and early entrance near the center of the city. The authors also have stressed the importance of the cases of if 'not-in-city' survivors, frequently reported to be fatal by the heavy chronic exposure. Recently we have noticed that the appearance of acute radiation symptoms is an important index for estimating total dose. In this paper, based on Obos statistical data (in 1957) for the acute symptoms observed for various category of survivors, we present an estimation of the average chronic dose of survivors, which should be added to the instantaneous dose for the directly exposed groups. By assuming the threshold for the appearance of the acute symptom such as epilation as 0.5 Sv, average chronic dose of 0.32 Sv was estimated for all survivors. Then the present dose-response relationship for cancer incidence should be shifted to the right hand side by this amount, and the value of about 0.32 Sv or more is suggested as the threshold for cancer incidence in low radiation level region

1. Development of linear free energy relationships for aqueous phase radical-involved chemical reactions.

Minakata, Daisuke; Mezyk, Stephen P; Jones, Jace W; Daws, Brittany R; Crittenden, John C

2014-12-02

2. The risk of low doses of ionising radiation and the linear no threshold relationship debate

Tubiana, M.; Masse, R.; Vathaire, F. de; Averbeck, D.; Aurengo, A.

2007-01-01

The ICRP and the B.E.I.R. VII reports recommend a linear no threshold (L.N.T.) relationship for the estimation of cancer excess risk induced by ionising radiations (IR), but the 2005 report of Medicine and Science French Academies concludes that it leads to overestimate of risk for low and very low doses. The bases of L.N.T. are challenged by recent biological and animal experimental studies which show that the defence against IR involves the cell microenvironment and the immunologic system. The defence mechanisms against low doses are different and comparatively more effective than for high doses. Cell death is predominant against low doses. DNA repairing is activated against high doses, in order to preserve tissue functions. These mechanisms provide for multicellular organisms an effective and low cost defence system. The differences between low and high doses defence mechanisms are obvious for alpha emitters which show several greys threshold effects. These differences result in an impairment of epidemiological studies which, for statistical power purpose, amalgamate high and low doses exposure data, since it would imply that cancer IR induction and defence mechanisms are similar in both cases. Low IR dose risk estimates should rely on specific epidemiological studies restricted to low dose exposures and taking precisely into account potential confounding factors. The preliminary synthesis of cohort studies for which low dose data (< 100 mSv) were available show no significant risk excess, neither for solid cancer nor for leukemias. (authors)

3. Application of a linear free energy relationship to crystalline solids of MO2 and M(OH)4

Xu Huifang; Barton, L.L.

1999-01-01

In this letter, a linear free energy relationship developed by Sverjensky and Molling is used to predict the Gibbs free energies of formation of crystalline phases of M 4+ O 2 and M 4+ (OH) 4 from the known thermodynamic properties of aqueous tetravalent cations (M 4+ ). The modified Sverjensky and Molling equation for tetravalent cations is expressed as ΔG 0 f,M v X = a M v X ΔG 0 n,M 4+ + b M v X + β M v X r M 4+ , where the coefficients a M v X , b M v X and β M v X characterize a particular structural family of M v X, r M 4+ is the ionic radius of M 4+ cation, ΔG 0 f,M v X is the standard Gibbs free energy of formation of M v X, and ΔG 0 n,M 4+ is the standard non-solvation energy of cation M 4+ . By fitting the equation to the existing thermodynamic data, the coefficients in the equation for the MO 2 family minerals are estimated to be: a M v X = 0.670, β M v X = 32 (kcal/mol A), and b = -430.02 (kcal/mol). The constrained relationship can be used to predict the standard Gibbs free energies of formation of crystalline phases and fictive phases (i.e., phases which are thermodynamically unstable and do not occur at standard conditions) within the isostructural families of M 4+ O 2 and M 4+ (OH) 4 if the standard Gibbs free energies of formation of the tetravalent cations are known. (orig.)

4. Fertility Differentials and Educational Attainment in Portugal: A Non-Linear Relationship

Tiago de Oliveira, Isabel

2009-01-01

Full Text Available AbstractThis analysis of the Portuguese case shows a non-linear relationship betweenthe number of children and education in recent years. Using the data from tenyears before this hypothesis was confirmed, and we can see that the generaldecline in Portuguese fertility within the last decade was due to the fertilitydecrease of the less educated people, although partly attenuated by the fertilityincrease of the upper social groups. The reasons for a non-linear relationshipare discussed within the context of female employment rates and salarydifferentials by educational attainment. The main hypothesis is that differencesin fertility are related to an ‘education-work’ effect amongst those in the lesseducated groups and to an ‘education-income’ effect amongst the moreeducated.RésuméL’analyse de cas de la situation au Portugal démontre une relation non linéaireentre le nombre d’enfants et le niveau de scolarité au cours des dernièresannées. Les données recueillies pendant les dix dernières années ont étéétudiées avant de confirmer cette hypothèse ; nous avons pu voir que le déclingénéral dans le taux de fécondité au Portugal pendant la dernière décade étaitcausé par un déclin de fécondité chez les personnes moins éduquées ; ceci a étépartiellement atténué par une hausse dans le taux de fécondité dans les classessupérieures. Les raisons de cette relation non linéaire sont discutées dans lecontexte des taux d’emploi des femmes et les différentiels de salaire selon lesniveaux de scolarité. L’hypothèse majeure est que les différences dans les tauxde fécondité sont reliés à un effet « scolarité-travail » parmi les groupes moinséduqués et à un effet « scolarité-salaire » parmi les classes mieux éduqués.

5. Linear solvation energy relationships for toxicity of selected organic chemicals to Daphnia pulex and Daphnia magna

Passino, Dora R.M.; Hickey, James P.; Frank, Anthony M.

1988-01-01

In the Laurentian Great Lakes, more than 300 contaminants have been identified in fish, other biota, water, and sediment. Current hazard assessment of these chemicals by the National Fisheries Research Center-Great Lakes is based on their toxicity, occurrence in the environment, and source. Although scientists at the Center have tested over 70 chemicals with the crustacean Daphnia pulex, the number of experimental data needed to screen the huge array of chemicals in the Great Lakes exceeds the practical capabilities of conducting bioassays. This limitation can be partly circumvented, however, by using mathematical models based on quantitative structure-activity relationships (QSAR) to provide rapid, inexpensive estimates of toxicity. Many properties of chemicals, including toxicity, bioaccumulation and water solubility are well correlated and can be predicted by equations of the generalized linear solvation energy relationships (LSER). The equation we used to model solute toxicity is Toxicity = constant + mVI/100 + s (π* + dδ) + bβm + aαm where VI = intrinsic (Van der Waals) molar volume; π* = molecular dipolarity/polarizability; δ = polarizability 'correction term'; βm = solute hydrogen bond acceptor basicity; and αm = solute hydrogen bond donor acidity. The subscript m designates solute monomer values for α and β. We applied the LSER model to 48-h acute toxicity data (measured as immobilization) for six classes of chemicals detected in Great Lakes fish. The following regression was obtained for Daphnia pulex (concentration = μM): log EC50 = 4.86 - 4.35 VI/100; N = 38, r2 = 0.867, sd = 0.403 We also used the LSER modeling approach to analyze to a large published data set of 24-h acute toxicity for Daphnia magna; the following regression resulted, for eight classes of compounds (concentration = mM): log EC50 = 3.88 - 4.52 VI/100 - 1.62 π* + 1.66 βm - 0.916 αm; N = 62, r2 = 0.859, sd = 0.375 In addition we developed computer software that identifies

6. Modeling bioaccumulation in humans using poly-parameter linear free energy relationships (PPLFERS)

Undeman, Emma, E-mail: emma.undeman@itm.su.se; Czub, Gertje; McLachlan, Michael S.

2011-04-01

Chemical partition coefficients between environmental media and biological tissues are a key component of bioaccumulation models. The single-parameter linear free energy relationships (spLFERs) commonly used for predicting partitioning are often derived using apolar chemicals and may not accurately capture polar chemicals. In this study, a poly-parameter LFER (ppLFER) based model of organic chemical bioaccumulation in humans is presented. Chemical partitioning was described by an air-body partition coefficient that was a volume weighted average of ppLFER based partition coefficients for the major organs and tissues constituting the human body. This model was compared to a spLFER model treating the body as a mixture of lipid ({approx} octanol) and water. Although model agreement was good for hydrophobic chemicals (average difference 15% for log K{sub OW} > 4 and log K{sub OA} > 8), the ppLFER model predicted {approx} 90% lower body burdens for hydrophilic chemicals (log K{sub OW} < 0). This was mainly due to lower predictions of muscle and adipose tissue sorption capacity for these chemicals. A comparison of the predicted muscle and adipose tissue sorption capacities of hydrophilic chemicals with measurements indicated that the ppLFER and spLFER models' uncertainties were similar. Consequently, little benefit from the implementation of ppLFERs in this model was identified. - Research Highlights: {yields}Implementation of ppLFERs resulted in on average 90% lower predicted body burdens. {yields}Uncertainties in spLFER and ppLFER predictions were similar. {yields}The benefit from implementation of ppLFERs in bioaccumulation models was limited.

7. The Non-Linear Relationship between BMI and Health Care Costs and the Resulting Cost Fraction Attributable to Obesity.

Laxy, Michael; Stark, Renée; Peters, Annette; Hauner, Hans; Holle, Rolf; Teuner, Christina M

2017-08-30

This study aims to analyse the non-linear relationship between Body Mass Index (BMI) and direct health care costs, and to quantify the resulting cost fraction attributable to obesity in Germany. Five cross-sectional surveys of cohort studies in southern Germany were pooled, resulting in data of 6757 individuals (31-96 years old). Self-reported information on health care utilisation was used to estimate direct health care costs for the year 2011. The relationship between measured BMI and annual costs was analysed using generalised additive models, and the cost fraction attributable to obesity was calculated. We found a non-linear association of BMI and health care costs with a continuously increasing slope for increasing BMI without any clear threshold. Under the consideration of the non-linear BMI-cost relationship, a shift in the BMI distribution so that the BMI of each individual is lowered by one point is associated with a 2.1% reduction of mean direct costs in the population. If obesity was eliminated, and the BMI of all obese individuals were lowered to 29.9 kg/m², this would reduce the mean direct costs by 4.0% in the population. Results show a non-linear relationship between BMI and health care costs, with very high costs for a few individuals with high BMI. This indicates that population-based interventions in combination with selective measures for very obese individuals might be the preferred strategy.

8. Possible factors determining the non-linearity in the VO2-power output relationship in humans: theoretical studies.

Korzeniewski, Bernard; Zoladz, Jerzy A

2003-08-01

At low power output exercise (below lactate threshold), the oxygen uptake increases linearly with power output, but at high power output exercise (above lactate threshold) some additional oxygen consumption causes a non-linearity in the overall VO(2) (oxygen uptake rate)-power output relationship. The functional significance of this phenomenon for human exercise tolerance is very important, but the mechanisms underlying it remain unknown. In the present work, a computer model of oxidative phosphorylation in intact skeletal muscle developed previously is used to examine the background of this relationship in different modes of exercise. Our simulations demonstrate that the non-linearity in the VO(2)-power output relationship and the difference in the magnitude of this non-linearity between incremental exercise mode and square-wave exercise mode (constant power output exercise) can be generated by introducing into the model some hypothetical factor F (group of associated factors) that accumulate(s) in time during exercise. The performed computer simulations, based on this assumption, give proper time courses of changes in VO(2) and [PCr] after an onset of work of different intensities, including the slow component in VO(2), well matching the experimental results. Moreover, if it is assumed that the exercise terminates because of fatigue when the amount/intensity of F exceed some threshold value, the model allows the generation of a proper shape of the well-known power-duration curve. This fact suggests that the phenomenon of the non-linearity of the VO(2)-power output relationship and the magnitude of this non-linearity in different modes of exercise is determined by some factor(s) responsible for muscle fatigue.

9. Untangling the causal relationship between tax burden distribution and economic growth in 23 OECD countries: Fresh evidence from linear and non-linear Granger causality

Sami Saafi

2017-12-01

Full Text Available The aim of the paper is to investigate the linear and nonlinear causality between a set of alternative tax burden ratios and economic growth in 23 OECD countries. To that end, the linear causality approach of Toda– Yamamoto (1995 and the nonparametric causality method of Kyrtsou and Labys (2006 are applied to annual data spanning from 1970 to 2014. Results obtained from the nonlinear causality test tend to reject the neutrality hypothesis for the tax structure–growth relationship in 19 of the 23 OECD countries. In the majority of the countries under investigation, the evidence is in line with the growth hypothesis where causality running from economic growth to tax burden ratios was detected in Australia, Denmark, Finland, Japan, New Zealand, and Norway. The opposite causality running from tax structure to economic growth was found in Germany, Netherlands, Portugal, and Sweden. In contrast, the neutrality hypothesis was supported in Austria, Italy, Luxembourg, and the USA, whereas the feedback hypothesis was supported in Turkey and the UK. Additional robustness checks show that when the signs of variations are taken into account, there is an asymmetric causality running from positive tax burden shocks to positive per capita GDP shocks for Belgium, France, and Turkey. Overall, our findings suggest that policy implications of the tax structure-economic growth relationships should be interpreted with caution, taking into account the test-dependent and country-specific results.

10. Modelling long term rockslide displacements with non-linear time-dependent relationships

De Caro, Mattia; Volpi, Giorgio; Castellanza, Riccardo; Crosta, Giovanni; Agliardi, Federico

2015-04-01

Rockslides undergoing rapid changes in behaviour pose major risks in alpine areas, and require careful characterization and monitoring both for civil protection and mitigation activities. In particular, these instabilities can undergo very slow movement with occasional and intermittent acceleration/deceleration stages of motion potentially leading to collapse. Therefore, the analysis of such instabilities remains a challenging issue. Rockslide displacements are strongly conditioned by hydrologic factors as suggested by correlations with groundwater fluctuations, snowmelt, with a frequently observed delay between perturbation and system reaction. The aim of this work is the simulation of the complex time-dependent behaviour of two case studies for which also a 2D transient hydrogeological simulation has been performed: Vajont rockslide (1960 to 1963) and the recent Mt. de La Saxe rockslide (2009 to 2012). Non-linear time-dependent constitutive relationships have been used to describe long-term creep deformation. Analyses have been performed using a "rheological-mechanical" approach that fits idealized models (e.g. viscoelastic, viscoplastic, elasto-viscoplastic, Burgers, nonlinear visco-plastic) to the experimental behaviour of specific materials by means of numerical constants. Bidimensional simulations were carried out using the finite difference code FLAC. Displacements time-series, available for the two landslides, show two superimposed deformation mechanisms: a creep process, leading to movements under "steady state" conditions (e.g. constant groundwater level), and a "dynamic" process, leading to an increase in displacement rate due to changes of external loads (e.g. groundwater level). For both cases sliding mass is considered as an elasto-plastic body subject to its self-weight, inertial and seepage forces varying with time according to water table fluctuation (due to snowmelt or changing in reservoir level) and derived from the previous hydrogeological

11. A note on the relationship between the emittance, the beta function and the energy in a linear collider

Rees, J.

1986-11-01

Scaling laws for linear colliders are considered for the case of laterally round Gaussian beams and for the case that mutual pinching of the beams can be ignored. Based on these assumptions, the relationship is found between the interaction area, beta function, beam emittance, and energy for a linear collider in order to show the need for substantial improvements in the feasible values of accelerator parameters to reach a center of mass energy of 0.7 TeV. Pinch is then taken into account

12. An analysis of the relationship between the linear hammer speed and the thrower applied forces during the hammer throw for male and female throwers.

Brice, Sara M; Ness, Kevin F; Rosemond, Doug

2011-09-01

The purpose of this study was to investigate the relationship between the cable force and linear hammer speed in the hammer throw and to identify how the magnitude and direction of the cable force affects the fluctuations in linear hammer speed. Five male (height: 1.88 +/- 0.06 m; body mass: 106.23 +/- 4.83 kg) and five female (height: 1.69 +/- 0.05 m; body mass: 101.60 +/- 20.92 kg) throwers participated and were required to perform 10 throws each. The hammer's linear velocity and the cable force and its tangential component were calculated via hammer head positional data. As expected, a strong correlation was observed between decreases in the linear hammer speed and decreases in the cable force (normalised for hammer weight). A strong correlation was also found to exist between the angle by which the cable force lags the radius of rotation at its maximum (when tangential force is at its most negative) and the size of the decreases in hammer speed. These findings indicate that the most effective way to minimise the effect of the negative tangential force is to reduce the size of the lag angle.

13. Linear and non-linear quantitative structure-activity relationship models on indole substitution patterns as inhibitors of HIV-1 attachment.

Nirouei, Mahyar; Ghasemi, Ghasem; Abdolmaleki, Parviz; Tavakoli, Abdolreza; Shariati, Shahab

2012-06-01

The antiviral drugs that inhibit human immunodeficiency virus (HIV) entry to the target cells are already in different phases of clinical trials. They prevent viral entry and have a highly specific mechanism of action with a low toxicity profile. Few QSAR studies have been performed on this group of inhibitors. This study was performed to develop a quantitative structure-activity relationship (QSAR) model of the biological activity of indole glyoxamide derivatives as inhibitors of the interaction between HIV glycoprotein gp120 and host cell CD4 receptors. Forty different indole glyoxamide derivatives were selected as a sample set and geometrically optimized using Gaussian 98W. Different combinations of multiple linear regression (MLR), genetic algorithms (GA) and artificial neural networks (ANN) were then utilized to construct the QSAR models. These models were also utilized to select the most efficient subsets of descriptors in a cross-validation procedure for non-linear log (1/EC50) prediction. The results that were obtained using GA-ANN were compared with MLR-MLR and MLR-ANN models. A high predictive ability was observed for the MLR, MLR-ANN and GA-ANN models, with root mean sum square errors (RMSE) of 0.99, 0.91 and 0.67, respectively (N = 40). In summary, machine learning methods were highly effective in designing QSAR models when compared to statistical method.

14. Genomic predictions across Nordic Holstein and Nordic Red using the genomic best linear unbiased prediction model with different genomic relationship matrices.

Zhou, L; Lund, M S; Wang, Y; Su, G

2014-08-01

This study investigated genomic predictions across Nordic Holstein and Nordic Red using various genomic relationship matrices. Different sources of information, such as consistencies of linkage disequilibrium (LD) phase and marker effects, were used to construct the genomic relationship matrices (G-matrices) across these two breeds. Single-trait genomic best linear unbiased prediction (GBLUP) model and two-trait GBLUP model were used for single-breed and two-breed genomic predictions. The data included 5215 Nordic Holstein bulls and 4361 Nordic Red bulls, which was composed of three populations: Danish Red, Swedish Red and Finnish Ayrshire. The bulls were genotyped with 50 000 SNP chip. Using the two-breed predictions with a joint Nordic Holstein and Nordic Red reference population, accuracies increased slightly for all traits in Nordic Red, but only for some traits in Nordic Holstein. Among the three subpopulations of Nordic Red, accuracies increased more for Danish Red than for Swedish Red and Finnish Ayrshire. This is because closer genetic relationships exist between Danish Red and Nordic Holstein. Among Danish Red, individuals with higher genomic relationship coefficients with Nordic Holstein showed more increased accuracies in the two-breed predictions. Weighting the two-breed G-matrices by LD phase consistencies, marker effects or both did not further improve accuracies of the two-breed predictions. © 2014 Blackwell Verlag GmbH.

15. A method for determining the non-existence of a common quadratic Lyapunov function for switched linear systems based on particle swarm optimisation

Duarte-Mermoud, M.A.; Ordonez-Hurtado, R.H.; Zagalak, Petr

2012-01-01

Roč. 43, č. 11 (2012), s. 2015-2029 ISSN 0020-7721 R&D Projects: GA ČR(CZ) GAP103/12/2431 Institutional support: RVO:67985556 Keywords : Switched linear systems * Lyapunov function * particle swarm optimization Subject RIV: BC - Control Systems Theory Impact factor: 1.305, year: 2012 http://library.utia.cas.cz/separaty/2012/AS/zagalak-0382169.pdf

16. Validity of a Commercial Linear Encoder to Estimate Bench Press 1 RM from the Force-Velocity Relationship.

Bosquet, Laurent; Porta-Benache, Jeremy; Blais, Jérôme

2010-01-01

The aim of this study was to assess the validity and accuracy of a commercial linear encoder (Musclelab, Ergotest, Norway) to estimate Bench press 1 repetition maximum (1RM) from the force - velocity relationship. Twenty seven physical education students and teachers (5 women and 22 men) with a heterogeneous history of strength training participated in this study. They performed a 1 RM test and a force - velocity test using a Bench press lifting task in a random order. Mean 1 RM was 61.8 ± 15.3 kg (range: 34 to 100 kg), while 1 RM estimated by the Musclelab's software from the force-velocity relationship was 56.4 ± 14.0 kg (range: 33 to 91 kg). Actual and estimated 1 RM were very highly correlated (r = 0.93, pvelocity relationship was a good measure for monitoring training induced adaptations, but also that it was not accurate enough to prescribe training intensities. Additional studies are required to determine whether accuracy is affected by age, sex or initial level. Key pointsSome commercial devices allow to estimate 1 RM from the force-velocity relationship.These estimations are valid. However, their accuracy is not high enough to be of practical help for training intensity prescription.Day-to-day reliability of force and velocity measured by the linear encoder has been shown to be very high, but the specific reliability of 1 RM estimated from the force-velocity relationship has to be determined before concluding to the usefulness of this approach in the monitoring of training induced adaptations.

17. Non-linear relationship between O2 uptake and power output at high intensities of exercise in humans.

Zoladz, J A; Rademaker, A C; Sargeant, A J

1995-01-01

1. A slow component to pulmonary oxygen uptake (VO2) is reported during prolonged high power exercise performed at constant power output at, or above, approximately 60% of the maximal oxygen uptake. The magnitude of the slow component is reported to be associated with the intensity of exercise and to be largely accounted for by an increased VO2 across the exercising legs. 2. On the assumption that the control mechanism responsible for the increased VO2 is intensity dependent we hypothesized that it should also be apparent in multi-stage incremental exercise tests with the result that the VO2-power output relationship would be curvilinear. 3. We further hypothesized that the change in the VO2-power output relationship could be related to the hierarchical recruitment of different muscle fibre types with a lower mechanical efficiency. 4. Six subjects each performed five incremental exercise tests, at pedalling rates of 40, 60, 80, 100 and 120 rev min-1, over which range we expected to vary the proportional contribution of different fibre types to the power output. Pulmonary VO2 was determined continuously and arterialized capillary blood was sampled and analysed for blood lactate concentration ([lactate]b). 5. Below the level at which a sustained increase in [lactate]b was observed pulmonary VO2 showed a linear relationship with power output; at high power outputs, however, there was an additional increase in VO2 above that expected from the extrapolation of that linear relationship, leading to a positive curvilinear VO2-power output relationship. 6. No systematic effect on the magnitude or onset of the 'extra' VO2 was found in relation to pedalling rate, which suggests that it is not related to the pattern of motor unit recruitment in any simple way. PMID:8568657

18. Validity of a Commercial Linear Encoder to Estimate Bench Press 1 RM from the Force-Velocity Relationship

Bosquet, Laurent; Porta-Benache, Jeremy; Blais, Jérôme

2010-01-01

The aim of this study was to assess the validity and accuracy of a commercial linear encoder (Musclelab, Ergotest, Norway) to estimate Bench press 1 repetition maximum (1RM) from the force - velocity relationship. Twenty seven physical education students and teachers (5 women and 22 men) with a heterogeneous history of strength training participated in this study. They performed a 1 RM test and a force - velocity test using a Bench press lifting task in a random order. Mean 1 RM was 61.8 ± 15.3 kg (range: 34 to 100 kg), while 1 RM estimated by the Musclelab’s software from the force-velocity relationship was 56.4 ± 14.0 kg (range: 33 to 91 kg). Actual and estimated 1 RM were very highly correlated (r = 0.93, p<0.001) but largely different (Bias: 5.4 ± 5.7 kg, p < 0.001, ES = 1.37). The 95% limits of agreement were ±11.2 kg, which represented ±18% of actual 1 RM. It was concluded that 1 RM estimated from the force-velocity relationship was a good measure for monitoring training induced adaptations, but also that it was not accurate enough to prescribe training intensities. Additional studies are required to determine whether accuracy is affected by age, sex or initial level. Key points Some commercial devices allow to estimate 1 RM from the force-velocity relationship. These estimations are valid. However, their accuracy is not high enough to be of practical help for training intensity prescription. Day-to-day reliability of force and velocity measured by the linear encoder has been shown to be very high, but the specific reliability of 1 RM estimated from the force-velocity relationship has to be determined before concluding to the usefulness of this approach in the monitoring of training induced adaptations. PMID:24149641

19. 28 CFR 522.12 - Relationship between existing criminal sentences imposed under the U.S. or D.C. Code and new...

2010-07-01

... sentences imposed under the U.S. or D.C. Code and new civil contempt commitment orders. 522.12 Section 522..., AND TRANSFER ADMISSION TO INSTITUTION Civil Contempt of Court Commitments § 522.12 Relationship between existing criminal sentences imposed under the U.S. or D.C. Code and new civil contempt commitment...

20. Genome-scale regression analysis reveals a linear relationship for promoters and enhancers after combinatorial drug treatment

Rapakoulia, Trisevgeni

2017-08-09

Motivation: Drug combination therapy for treatment of cancers and other multifactorial diseases has the potential of increasing the therapeutic effect, while reducing the likelihood of drug resistance. In order to reduce time and cost spent in comprehensive screens, methods are needed which can model additive effects of possible drug combinations. Results: We here show that the transcriptional response to combinatorial drug treatment at promoters, as measured by single molecule CAGE technology, is accurately described by a linear combination of the responses of the individual drugs at a genome wide scale. We also find that the same linear relationship holds for transcription at enhancer elements. We conclude that the described approach is promising for eliciting the transcriptional response to multidrug treatment at promoters and enhancers in an unbiased genome wide way, which may minimize the need for exhaustive combinatorial screens.

1. Cytogenetic effect of low dose gamma-radiation in Hordeum vulgare seedlings: non-linear dose-effect relationship.

Geras'kin, Stanislav A; Oudalova, Alla A; Kim, Jin Kyu; Dikarev, Vladimir G; Dikareva, Nina S

2007-03-01

The induction of chromosome aberrations in Hordeum vulgare germinated seeds was studied after ionizing irradiation with doses in the range of 10-1,000 mGy. The relationship between the frequency of aberrant cells and the absorbed dose was found to be nonlinear. A dose-independent plateau in the dose range from about 50 to 500 mGy was observed, where the level of cytogenetic damage was significantly different from the spontaneous level. The comparison of the goodness of the experimental data fitting with mathematical models of different complexity, using the most common quantitative criteria, demonstrated the advantage of a piecewise linear model over linear and polynomial models in approximating the frequency of cytogenetical disturbances. The results of the study support the hypothesis of indirect mechanisms of mutagenesis induced by low doses. Fundamental and applied implications of these findings are discussed.

2. Non-linear quantitative structure-activity relationship for adenine derivatives as competitive inhibitors of adenosine deaminase

Sadat Hayatshahi, Sayyed Hamed; Abdolmaleki, Parviz; Safarian, Shahrokh; Khajeh, Khosro

2005-01-01

Logistic regression and artificial neural networks have been developed as two non-linear models to establish quantitative structure-activity relationships between structural descriptors and biochemical activity of adenosine based competitive inhibitors, toward adenosine deaminase. The training set included 24 compounds with known k i values. The models were trained to solve two-class problems. Unlike the previous work in which multiple linear regression was used, the highest of positive charge on the molecules was recognized to be in close relation with their inhibition activity, while the electric charge on atom N1 of adenosine was found to be a poor descriptor. Consequently, the previously developed equation was improved and the newly formed one could predict the class of 91.66% of compounds correctly. Also optimized 2-3-1 and 3-4-1 neural networks could increase this rate to 95.83%

3. Linearizing W-algebras

Krivonos, S.O.; Sorin, A.S.

1994-06-01

We show that the Zamolodchikov's and Polyakov-Bershadsky nonlinear algebras W 3 and W (2) 3 can be embedded as subalgebras into some linear algebras with finite set of currents. Using these linear algebras we find new field realizations of W (2) 3 and W 3 which could be a starting point for constructing new versions of W-string theories. We also reveal a number of hidden relationships between W 3 and W (2) 3 . We conjecture that similar linear algebras can exist for other W-algebra as well. (author). 10 refs

4. Re-examining the Non-Linear Moisture-Precipitation Relationship over the Tropical Oceans.

Rushley, S S; Kim, D; Bretherton, C S; Ahn, M-S

2018-01-28

Bretherton et al. (2004) used the Special Sensor Microwave Imager (SSM/I) version 5 product to derive an exponential curve that describes the relationship between precipitation and column relative humidity (CRH) over the tropical oceans. The curve, which features a precipitation pickup at a CRH of about 0.75 and a rapid increase of precipitation with CRH after the pickup, has been widely used in the studies of the tropical atmosphere. This study re-examines the moisture-precipitation relationship by using the version 7 SSM/I data, in which several biases in the previous version are corrected, and evaluates the relationship in the Coupled Model Intercomparison Project phase 5 (CMIP5) models. In the revised exponential curve derived using the updated satellite data, the precipitation pick-up occurs at a higher CRH (~0.8), and precipitation increases more slowly with CRH than in the previous curve. In most CMIP5 models, the precipitation pickup is too early due to the common model bias of overestimated (underestimated) precipitation in the dry (wet) regime.

5. Solvatochromism and linear solvation energy relationship of the kinase inhibitor SKF86002

Khattab, Muhammad; Van Dongen, Madeline; Wang, Feng; Clayton, Andrew H. A.

2017-01-01

We studied the spectroscopic characteristics of SKF86002, an anti-inflammatory and tyrosine kinase inhibitor drug candidate. Two conformers SKF86002A and SKF86002B are separated by energy barriers of 19.68 kJ·mol- 1 and 6.65 kJ·mol- 1 due to H-bonds, and produce the three major UV-Vis absorption bands at 325 nm, 260 nm and 210 nm in cyclohexane solutions. This environment-sensitive fluorophore exhibited emission in the 400-500 nm range with a marked response to changes in environment polarity. By using twenty-two solvents for the solvatochromism study, it was noticed that solvent polarity, represented by dielectric constant, was well correlated with the emission wavelength maxima of SKF86002. Thus, the SKF86002 fluorescence peak red shifted in aprotic solvents from 397.5 nm in cyclohexane to 436 nm in DMSO. While the emission maximum in hydrogen donating solvents ranged from 420 nm in t-butanol to 446 nm in N-methylformamide. Employing Lippert-Mataga, Bakhshiev and Kawski models, we found that one linear correlation provided a satisfactory description of polarity effect of 18 solvents on the spectral changes of SKF86002 with R2 values 0.78, 0.80 and 0.80, respectively. Additionally, the multicomponent linear regression analysis of Kamlet-Taft (R2 = 0.94) revealed that solvent acidity, basicity and polarity accounted for 31%, 24% and 45% of solvent effects on SKF86002 emission, respectively. While Catalán correlation (R2 = 0.92) revealed that solvatochromic change of SKF86002 emission was attributed to changes in solvent dipolarity (71%), solvent polarity (12%), solvent acidity (11%) and solvent basicity (6%). Plot of Reichardt transition energies and emission energies of SKF86002 in 18 solvents showed also a linear correlation with R2 = 0.90. The dipole moment difference between excited and ground state was calculated to be 3.4-3.5 debye.

6. Solvatochromism and linear solvation energy relationship of the kinase inhibitor SKF86002.

Khattab, Muhammad; Van Dongen, Madeline; Wang, Feng; Clayton, Andrew H A

2017-01-05

We studied the spectroscopic characteristics of SKF86002, an anti-inflammatory and tyrosine kinase inhibitor drug candidate. Two conformers SKF86002A and SKF86002B are separated by energy barriers of 19.68kJ·mol(-1) and 6.65kJ·mol(-1) due to H-bonds, and produce the three major UV-Vis absorption bands at 325nm, 260nm and 210nm in cyclohexane solutions. This environment-sensitive fluorophore exhibited emission in the 400-500nm range with a marked response to changes in environment polarity. By using twenty-two solvents for the solvatochromism study, it was noticed that solvent polarity, represented by dielectric constant, was well correlated with the emission wavelength maxima of SKF86002. Thus, the SKF86002 fluorescence peak red shifted in aprotic solvents from 397.5nm in cyclohexane to 436nm in DMSO. While the emission maximum in hydrogen donating solvents ranged from 420nm in t-butanol to 446nm in N-methylformamide. Employing Lippert-Mataga, Bakhshiev and Kawski models, we found that one linear correlation provided a satisfactory description of polarity effect of 18 solvents on the spectral changes of SKF86002 with R(2) values 0.78, 0.80 and 0.80, respectively. Additionally, the multicomponent linear regression analysis of Kamlet-Taft (R(2)=0.94) revealed that solvent acidity, basicity and polarity accounted for 31%, 24% and 45% of solvent effects on SKF86002 emission, respectively. While Catalán correlation (R(2)=0.92) revealed that solvatochromic change of SKF86002 emission was attributed to changes in solvent dipolarity (71%), solvent polarity (12%), solvent acidity (11%) and solvent basicity (6%). Plot of Reichardt transition energies and emission energies of SKF86002 in 18 solvents showed also a linear correlation with R(2)=0.90. The dipole moment difference between excited and ground state was calculated to be 3.4-3.5debye. Copyright © 2016 Elsevier B.V. All rights reserved.

7. Validity of a Commercial Linear Encoder to Estimate Bench Press 1 RM from the Force-Velocity Relationship

Bosquet, Laurent; Porta-Benache, Jeremy; Blais, Jérôme

2010-01-01

The aim of this study was to assess the validity and accuracy of a commercial linear encoder (Musclelab, Ergotest, Norway) to estimate Bench press 1 repetition maximum (1RM) from the force - velocity relationship. Twenty seven physical education students and teachers (5 women and 22 men) with a heterogeneous history of strength training participated in this study. They performed a 1 RM test and a force - velocity test using a Bench press lifting task in a random order. Mean 1 RM was 61.8 ± 15...

8. Intracavitary brachytherapy significantly enhances local control of early T-stage nasopharyngeal carcinoma: the existence of a dose-tumor-control relationship above conventional tumoricidal dose

Teo, Peter Man Lung; Leung, Sing Fai; Lee, Wai Yee; Zee, Benny

2000-01-01

the chronic radiation complications, with the exception of chronic radiation nasopharyngeal ulceration/necrosis which occurred in 10 patients in Group A and 1 patient in Group B. Headache (n = 4) and foul smell (n = 8) consequential to ulceration/necrosis were mild and manageable by conservative means. A significant dose-tumor-control relationship existed when local failure was studied as a function of the total physical dose or the total biological equivalent dose (linear quadratic equation, α/β = 10) uncorrected for tumor repopulation during the time course of the radiotherapy. Conclusions: Supplementing ERT which delivered tumoricidal dose (uncorrected BED-10 ≥75 Gy), ICT significantly enhanced ultimate local control and avoided the necessity for morbid salvage treatments in early T-stage (T1/T2 nasal infiltration) NPC. The slight increase in chronic radiation ulceration/necrosis after ICT was acceptable with mild and manageable symptoms. Other late complications were not increased. A significant dose-tumor-control relationship exists above the conventional tumoricidal dose level

9. Study geomorphology, past and present, linear trench, tectonics relationship between Pyrenees and Alps

Guillemot, J. (Principal Investigator)

1974-01-01

The author has identified the following significant results. ERTS-1 images obviously show up some large linear features trending N 80 E or N 30 E common to both Alps and Pyrenees. One of them, the Ligurian Fault, had been previously forecast by Laubscher in an interpretation of the Alps by the plate tectonic theory, but it extends westward farthest from the Alps, cutting the Pyrenees axis. These lineaments have been interpreted as reflections of deep seated wrench faults in the surficial part of the sedimentary series. A large set of such lineaments is perceptible in western Europe, such as the Guadalquivir Fault in southern Spain, Ligurian Fault, Insubrian Fault, Northern-Jura Fault, Metz Fault. Perhaps these may be interpreted as transform faults of the mid-Atlantic ridge or of a paleo-rift seated in the Rhine-Rhone graben.

10. A Threshold Exists in the Dose-response Relationship for Somatic Mutation Frequency Inducted by X-ray Irradiation of Drosophia

Koana, T.; Takashima, Y.; Okada, M. O.; Ikehata, M.; Miyakoshi, J.; Sakai, K.

2004-01-01

The dose-response relationship of ionizing radiation and its stochastic effects has been thought to be linear without any thresholds. The basic data for this model was obtained from mutational assays in the male germ cells of fruits fly Drosophila melanogaster. However, carcinogenic activity should be examined more appropriately in somatic cells than in germ cells. Here, the dose-response relationship of X- ray irradiation and somatic mutation is examined in Drosophila. A threshold at approximately 1Gy was observed in the DNA repair proficient flies. In the repair deficient siblings, the threshold was smaller and the inclination of the dose-response curve was much steeper. These results suggest that the dose-response relationship between X-ray irradiation and somatic mutation has a threshold, and that the DNA repair function contributes to its formation. (Author) 35 refs

11. Body mass index and motor coordination: Non-linear relationships in children 6-10 years.

Lopes, V P; Malina, R M; Maia, J A R; Rodrigues, L P

2018-05-01

Given the concern for health-related consequences of an elevated body mass index (BMI; obesity), the potential consequences of a low BMI in children are often overlooked. The purpose was to evaluate the relationship between the BMI across its entire spectrum and motor coordination (MC) in children 6-10 years. Height, weight, and MC (Körperkoordinationstest für Kinder, KTK test battery) were measured in 1,912 boys and 1,826 girls of 6-10 years of age. BMI (kg/m 2 ) was calculated. KTK scores for each of the four tests were also converted to a motor quotient (MQ). One-way ANOVA was used to test differences in the BMI, individual test items, and MQ among boys and girls within age groups. Sex-specific quadratic regressions of individual KTK items and the MQ on the BMI were calculated. Girls and boys were also classified into four weight status groups using International Obesity Task Force criteria: thin, normal, overweight, and obese. Differences in specific test items and MQ between weight status groups were evaluated by age group in each sex. Thirty-one percent of the sample was overweight or obese, whereas 5% was thin. On average, normal weight children had the highest MQ in both sexes across the age range with few exceptions. Overweight/obese children had a lower MQ than normal weight and thin children. The quadratic regression lines generally presented an inverted parabolic relationship between the BMI and MC and suggested a decrease in MC with an increase in the BMI. In general, BMI shows a curvilinear, inverted parabolic relationship with MC in children 6-10 years. © 2018 John Wiley & Sons Ltd.

12. Non-linearity of dose-effect relationship at low level exposure on the example of cytogenetic effects in plant cells

Oudalova, A.A.; Geras'kin, S.A.; Dikarev, V.G.; Dikareva, N.S.; Chernonog, E.V.

2007-01-01

Complete text of publication follows. There has been an increasing concern in the current scientific society and among the public about the need to protect the environment in order to maintain the ecosystem sustainability and future well-being of man. The linear non-threshold (LNT) hypothesis as the most officially acknowledged concept of biological effect of radiation fails to explain many facts on effects at low level exposures (LLE) accumulated lately. Available information on the dose-effect relationship at low doses is scarce and incomplete for non-human species despite the fact that, under conditions of increased radiation exposure, some biota species occur at a risk of higher impact than humans because of differences in ecological niches occupied. Dose-effect relationships for cytogenetic damage in the range of LLE are studied in a series os experiments with plant (Hordeum vulgare L.) meristem cells. Dose-effect dependences obtained show an obvious non-linear behavior in the LLE region. A piecewise linear model (PLM) for dose-cytogenetic effect relationship that considers an existence of dose-independent part at LLE ('plateau') is developed and specified on the data obtained. An advantage of the PLM over linear model in approximating the frequency of cytogenetic disturbances is demonstrated. From an empirical probability distribution analysis, it is shown that the increase in cytogenetic damage level is tightly connected with changes in a process of absorbed energy distribution between target volumes in terms of fraction of cells experienced a radiation hit event. An appropriateness of the LNT hypothesis to the description of cytogenetic disturbances yield in plant meristem cells in the LLE region is discussed. The results support a conclusion about indirect mechanism of mutagenesis induced by low doses. New data obtained concern a perception of fundamental mechanisms governing cell response to LLE. These findings are of general biological interest, since

13. Best linear unbiased prediction of genomic breeding values using a trait-specific marker-derived relationship matrix.

Zhe Zhang

2010-09-01

Full Text Available With the availability of high density whole-genome single nucleotide polymorphism chips, genomic selection has become a promising method to estimate genetic merit with potentially high accuracy for animal, plant and aquaculture species of economic importance. With markers covering the entire genome, genetic merit of genotyped individuals can be predicted directly within the framework of mixed model equations, by using a matrix of relationships among individuals that is derived from the markers. Here we extend that approach by deriving a marker-based relationship matrix specifically for the trait of interest.In the framework of mixed model equations, a new best linear unbiased prediction (BLUP method including a trait-specific relationship matrix (TA was presented and termed TABLUP. The TA matrix was constructed on the basis of marker genotypes and their weights in relation to the trait of interest. A simulation study with 1,000 individuals as the training population and five successive generations as candidate population was carried out to validate the proposed method. The proposed TABLUP method outperformed the ridge regression BLUP (RRBLUP and BLUP with realized relationship matrix (GBLUP. It performed slightly worse than BayesB with an accuracy of 0.79 in the standard scenario.The proposed TABLUP method is an improvement of the RRBLUP and GBLUP method. It might be equivalent to the BayesB method but it has additional benefits like the calculation of accuracies for individual breeding values. The results also showed that the TA-matrix performs better in predicting ability than the classical numerator relationship matrix and the realized relationship matrix which are derived solely from pedigree or markers without regard to the trait. This is because the TA-matrix not only accounts for the Mendelian sampling term, but also puts the greater emphasis on those markers that explain more of the genetic variance in the trait.

14. Relationships between the structure of wheat gluten and ACE inhibitory activity of hydrolysate: stepwise multiple linear regression analysis.

Zhang, Yanyan; Ma, Haile; Wang, Bei; Qu, Wenjuan; Wali, Asif; Zhou, Cunshan

2016-08-01

Ultrasound pretreatment of wheat gluten (WG) before enzymolysis can improve the angiotensin converting enzyme (ACE) inhibitory activity of the hydrolysates by alerting the structure of substrate proteins. Establishment of a relationship between the structure of WG and ACE inhibitory activity of the hydrolysates to judge the end point of the ultrasonic pretreatment is vital. The results of stepwise multiple linear regression (MLR) showed that the contents of free sulfhydryl, α-helix, disulfide bond, surface hydrophobicity and random coil were significantly correlated to ACE Inhibitory activity of the hydrolysate, with the standard partial regression coefficients were 3.729, -0.676, -0.252, 0.022 and 0.156, respectively. The R(2) of this model was 0.970. External validation showed that the stepwise MLR model could well predict the ACE inhibitory activity of hydrolysate based on the content of free sulfhydryl, α-helix, disulfide bond, surface hydrophobicity and random coil of WG before hydrolysis. A stepwise multiple linear regression model describing the quantitative relationships between the structure of WG and the ACE Inhibitory activity of the hydrolysates was established. This model can be used to predict the endpoint of the ultrasonic pretreatment. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

15. Linear energy relationships for the octahedral preference of Mg, Ca and transition metal ions.

Pontikis, George; Borden, James; Martínek, Václav; Florián, Jan

2009-04-16

The geometry, atomic charges, force constants, and relative energies of the symmetric and distorted M(2+)(H(2)O)(4)(F(-))(2), M(3+)(H(2)O)(4)(F(-))(2), M(2+)(H(2)O)(3)(F(-))(2), and M(3+)(H(2)O)(3)(F(-))(2) metal complexes, M = Mg, Ca, Co, Cu, Fe, Mn, Ni, Zn, Cr, V, were calculated by using the B3LYP/TZVP density functional method in both gas phase and aqueous solution, modeled using the polarized continuum model. The deformation energy associated with moving one water ligand 12 degrees from the initial "octahedral" arrangement, in which all O-M-O, O-M-F, and F-M-F angles are either 90 degrees or 180 degrees, was calculated to examine the angular ligand flexibility. For all M(2+)(H(2)O)(4)(F(-))(2) complexes, this distortion increased the energy of the complex in proportion to the electrostatic potential-derived (ESP) charge of the metal, and in proportion to D(-10), where D is the distance from the distorted ligand to its closest neighbor. The octahedral stability was further examined by calculating the energies for the removal of a water ligand from the octahedral complex to form a square-pyramidal or trigonal-bipyramidal complex. The octahedral preference, defined as the negative of the corresponding binding energy of the ligand, was found to linearly correlate with the ESP charge of the metal in both the gas phase and aqueous solution. The obtained results indicate that quantum-mechanical covalent effects are of secondary importance for both the flexibility and the octahedral preference of M(2+)(H(2)O)(4)(F(-))(2) and M(3+)(H(2)O)(4)(F(-))(2) complexes. This conclusion and supporting data are important for the development of consistent molecular mechanical force fields of the studied metal ions.

16. Solvent Effects on Oxygen-17 Chemical Shifts in Amides. Quantitative Linear Solvation Shift Relationships

Díez, Ernesto; Fabián, Jesús San; Gerothanassis, Ioannis P.; Esteban, Angel L.; Abboud, José-Luis M.; Contreras, Ruben H.; de Kowalewski, Dora G.

1997-01-01

A multiple-linear-regression analysis (MLRA) has been carried out using the Kamlet-Abboud-Taft (KAT) solvatochromic parameters in order to elucidate and quantify the solvent effects on the17O chemical shifts ofN-methylformamide (NMF),N,N-dimethylformamide (DMF),N-methylacetamide (NMA), andN,N-dimethylacetamide (DMA). The chemical shifts of the four molecules show the same dependence (in ppm) on the solvent polarity-polarizability, i.e., -22π*. The influence of the solvent hydrogen-bond-donor (HBD) acidities is slightly larger for the acetamides NMA and DMA, i.e., -48α, than for the formamides NMF and DMF, i.e., -42α. The influence of the solvent hydrogen-bond-acceptor (HBA) basicities is negligible for the nonprotic molecules DMF and DMA but significant for the protic molecules NMF and NMA, i.e., -9β. The effect of substituting the N-H hydrogen by a methyl group amounts to -5.9 ppm in NMF and 5.4 ppm in NMA. The effect of substituting the O=C-H hydrogen amounts to 5.5 ppm in NMF and 16.8 ppm in DMF. The model of specific hydration sites of amides by I. P. Gerothanassis and C. Vakka [J. Org. Chem.59,2341 (1994)] is settled in a more quantitative basis and the model by M. I. Burgar, T. E. St. Amour, and D. Fiat [J. Phys. Chem.85,502 (1981)] is critically evaluated.17O hydration shifts have been calculated for formamide (FOR) by the ab initio LORG method at the 6-31G* level. For a formamide surrounded by the four in-plane molecules of water in the first hydration shell, the calculated17O shift change due to the four hydrogen bonds, -83.2 ppm, is smaller than the empirical hydration shift, -100 ppm. The17O shift change from each out-of-plane water molecule hydrogen-bonded to the amide oxygen is -18.0 ppm. These LORG results support the conclusion that no more than four water molecules are hydrogen-bonded to the amide oxygen in formamide.

17. Phytoplasma PMU1 exists as linear chromosomal and circular extrachromosomal elements and has enhanced expression in insect vectors compared with plant hosts.

Toruño, Tania Y; Musić, Martina Seruga; Simi, Silvia; Nicolaisen, Mogens; Hogenhout, Saskia A

2010-09-01

Phytoplasmas replicate intracellularly in plants and insects and are dependent on both hosts for dissemination in nature. Phytoplasmas have small genomes lacking genes for major metabolic pathways. Nevertheless, their genomes harbour multicopy gene clusters that were named potential mobile units (PMUs). PMU1 is the largest most complete repeat among the PMUs in the genome of Aster Yellows phytoplasma strain Witches' Broom (AY-WB). PMU1 is c. 20 kb in size and contains 21 genes encoding DNA replication and predicted membrane-targeted proteins. Here we show that AY-WB has a chromosomal linear PMU1 (L-PMU1) and an extrachromosomal circular PMU1 (C-PMU1). The C-PMU1 copy number was consistently higher by in average approximately fivefold in insects compared with plants and PMU1 gene expression levels were also considerably higher in insects indicating that C-PMU1 synthesis and expression are regulated. We found that the majority of AY-WB virulence genes lie on chromosomal PMU regions that have similar gene content and organization as PMU1 providing evidence that PMUs contribute to phytoplasma host adaptation and have integrated into the AY-WB chromosome. © 2010 Blackwell Publishing Ltd.

18. In Search of 'Birth Month Genes': Using Existing Data Repositories to Locate Genes Underlying Birth Month-Disease Relationships.

Boland, Mary Regina; Tatonetti, Nicholas P

2016-01-01

Prenatal and perinatal exposures vary seasonally (e.g., sunlight, allergens) and many diseases are linked with variance in exposure. Epidemiologists often measure these changes using birth month as a proxy for seasonal variance. Likewise, Genome-Wide Association Studies have associated or implicated these same diseases with many genes. Both disparate data types (epidemiological and genetic) can provide key insights into the underlying disease biology. We developed an algorithm that links 1) epidemiological data from birth month studies with 2) genetic data from published gene-disease association studies. Our framework uses existing data repositories - PubMed, DisGeNET and Gene Ontology - to produce a bipartite network that connects enriched seasonally varying biofactorss with birth month dependent diseases (BMDDs) through their overlapping developmental gene sets. As a proof-of-concept, we investigate 7 known BMDDs and highlight three important biological networks revealed by our algorithm and explore some interesting genetic mechanisms potentially responsible for the seasonal contribution to BMDDs.

19. Relationships between each part of the spinal curves and upright posture using Multiple stepwise linear regression analysis.

Boulet, Sebastien; Boudot, Elsa; Houel, Nicolas

2016-05-03

Back pain is a common reason for consultation in primary healthcare clinical practice, and has effects on daily activities and posture. Relationships between the whole spine and upright posture, however, remain unknown. The aim of this study was to identify the relationship between each spinal curve and centre of pressure position as well as velocity for healthy subjects. Twenty-one male subjects performed quiet stance in natural position. Each upright posture was then recorded using an optoelectronics system (Vicon Nexus) synchronized with two force plates. At each moment, polynomial interpolations of markers attached on the spine segment were used to compute cervical lordosis, thoracic kyphosis and lumbar lordosis angle curves. Mean of centre of pressure position and velocity was then computed. Multiple stepwise linear regression analysis showed that the position and velocity of centre of pressure associated with each part of the spinal curves were defined as best predictors of the lumbar lordosis angle (R(2)=0.45; p=1.65*10-10) and the thoracic kyphosis angle (R(2)=0.54; p=4.89*10-13) of healthy subjects in quiet stance. This study showed the relationships between each of cervical, thoracic, lumbar curvatures, and centre of pressure's fluctuation during free quiet standing using non-invasive full spinal curve exploration. Copyright © 2016 Elsevier Ltd. All rights reserved.

20. VALIDITY OF A COMMERCIAL LINEAR ENCODER TO ESTIMATE BENCH PRESS 1 RM FROM THE FORCE-VELOCITY RELATIONSHIP

Laurent Bosquet

2010-09-01

Full Text Available The aim of this study was to assess the validity and accuracy of a commercial linear encoder (Musclelab, Ergotest, Norway to estimate Bench press 1 repetition maximum (1RM from the force - velocity relationship. Twenty seven physical education students and teachers (5 women and 22 men with a heterogeneous history of strength training participated in this study. They performed a 1 RM test and a force - velocity test using a Bench press lifting task in a random order. Mean 1 RM was 61.8 ± 15.3 kg (range: 34 to 100 kg, while 1 RM estimated by the Musclelab's software from the force-velocity relationship was 56.4 ± 14.0 kg (range: 33 to 91 kg. Actual and estimated 1 RM were very highly correlated (r = 0.93, p<0.001 but largely different (Bias: 5.4 ± 5.7 kg, p < 0.001, ES = 1.37. The 95% limits of agreement were ±11.2 kg, which represented ±18% of actual 1 RM. It was concluded that 1 RM estimated from the force-velocity relationship was a good measure for monitoring training induced adaptations, but also that it was not accurate enough to prescribe training intensities. Additional studies are required to determine whether accuracy is affected by age, sex or initial level.

1. Linear and nonlinear relationships between biodegradation potential and molecular descriptors/fragments for organic pollutants and a theoretical interpretation

He, Jia; Qin, Weichao; Zhang, Xujia; Wen, Yang; Su, Limin; Zhao, Yuanhui

2013-01-01

Prediction of the biodegradability of organic pollutants is an ecologically desirable and economically feasible tool for estimating the environmental fate of chemicals. In this paper, linear and nonlinear relationships between biological oxygen demand (BOD) and molecular descriptors/fragments have been investigated for 1130 organic chemicals. Significant relationships have been observed between the simple molecular descriptors and %BOD for some homologous compounds, but not for the whole set of compounds. Electronic parameters, such as E HOMO and E LUMO , are the dominant factors affecting the biodegradability for some homologous chemicals. However, other descriptors, such as molecular weight, acid dissociation constant and polarity still have a significant impact on the biodegradation. The best global model for %BOD prediction is that developed from a chain-based fragmentation scheme. At the same time, the theoretical relationship between %BOD and molecular descriptors/fragments has been investigated, based on a first-order kinetic process. The %BOD is nonlinearly, rather than linearly, related to the descriptors. The coefficients of determination can be significantly improved by using nonlinear models for the homologous compounds and the whole data set. After analysing 1130 ready and not ready biodegradable compounds using 23 simple descriptors and various fragmentation schemes, it was revealed that biodegradation could be well predicted from a chain-based fragmentation scheme, a decision tree and a %BOD model. The models were capable of separating NRB and RB with an overall accuracy of 87.2%, 83.0% and 82.5%, respectively. The best classification model developed was a chain-based model but it used 155 fragments. The simplest model was a decision tree which only used 10 structural fragments. The effect of structures on the biodegradation has been analysed and the biodegradation pathway and mechanisms have been discussed based on activating and inactivating

2. Establishing linear solvation energy relationships between VOCs and monolayer-protected gold nanoclusters using quartz crystal microbalance.

Li, Chi-Lin; Lu, Chia-Jung

2009-08-15

Linear solvation energy relationships (LSERs) have been recognized as a useful model for investigating the chemical forces behind the partition coefficients between vapor molecules and absorbents. This study is the first to determine the solvation properties of monolayer-protected gold nanoclusters (MPCs) with different surface ligands. The ratio of partition coefficients/MPC density (K/rho) of 18 volatile organic compounds (VOCs) for four different MPCs obtained through quartz crystal microbalance (QCM) experiments were used for the LSER model calculations. LSER modeling results indicate that all MPC surfaces showed a statistically significant (pattraction, 4-methoxythiophenol-capped MPCs can also interact with polar organics (s=1.04). Showing a unique preference for the hydrogen bond basicity of vapors (b=1.11), 2-benzothiazolethiol-capped MPCs provide evidence of an intra-molecular, proton-shift mechanism on surface of nano-gold.

3. Linear relationship between in distribution of thallium-201 and blood flow in ischemic and nonischemic myocardium during exercise

Nielsen, A.P.; Morris, K.G.; Murdock, R.; Bruno, F.P.; Cobb, F.R.

1980-01-01

The purpose of this study was to compare the myocardial distribution of thallium-201 and regional myocrdial blood flow during ischemia and the physiologic stress of exercise. Studies were carried out in six dogs with chronically implanted catheters in the atrium and aorta and a snare on the circumflex coronary artery distal to the first marginal branch. Regional myocardial blood flow was measured during quiet, resting conditions using 7 to 10 ] of radioisotope-labeled microspheres. Each dog was then exercised on a treadmill at speeds of 5 to 9 mph at a 5/sup o/ incline. (After 1 minute of exercise the cirumflex coronary artery was occluded and thallium-201 and a second label of microspheres were injected. Exercise was continued for 5 minutes. The dogs were then sacrificed and the left ventricle was sectioned into approximately 80 1-2-g samples to compare thallium-201 activity and regional myocardial blood flow. The maximum increase in blood flow ranged from 3.3 to 7.2 times resting control values. Each dog had myocardial samples in which blood flow was markedly reduced, to less than 0.10 ml/min/g. In each dog there was a close linear relationship between thallium-201 distribution and direct measurements of regional myocardial blood flow. Linear regression analyses demonstrated a correlation coefficient of 0.98 or greater in each dog. These data indicate that during the physiologic stress of exercise, the myocardial distribution of thallium activity is linearly related to regional myocardial blood flow in both the ischemic and nonischemic regions

4. Quantitative structure-retention relationship studies using immobilized artificial membrane chromatography I: amended linear solvation energy relationships with the introduction of a molecular electronic factor.

Li, Jie; Sun, Jin; Cui, Shengmiao; He, Zhonggui

2006-11-03

Linear solvation energy relationships (LSERs) amended by the introduction of a molecular electronic factor were employed to establish quantitative structure-retention relationships using immobilized artificial membrane (IAM) chromatography, in particular ionizable solutes. The chromatographic indices, log k(IAM), were determined by HPLC on an IAM.PC.DD2 column for 53 structurally diverse compounds, including neutral, acidic and basic compounds. Unlike neutral compounds, the IAM chromatographic retention of ionizable compounds was affected by their molecular charge state. When the mean net charge per molecule (delta) was introduced into the amended LSER as the sixth variable, the LSER regression coefficient was significantly improved for the test set including ionizable solutes. The delta coefficients of acidic and basic compounds were quite different indicating that the molecular electronic factor had a markedly different impact on the retention of acidic and basic compounds on IAM column. Ionization of acidic compounds containing a carboxylic group tended to impair their retention on IAM, while the ionization of basic compounds did not have such a marked effect. In addition, the extra-interaction with the polar head of phospholipids might cause a certain change in the retention of basic compounds. A comparison of calculated and experimental retention indices suggested that the semi-empirical LSER amended by the addition of a molecular electronic factor was able to reproduce adequately the experimental retention factors of the structurally diverse solutes investigated.

5. Linear and nonlinear causal relationship between energy consumption and economic growth in China: New evidence based on wavelet analysis

2018-01-01

The energy-growth nexus has important policy implications for economic development. The results from many past studies that investigated the causality direction of this nexus can lead to misleading policy guidance. Using data on China from 1953 to 2013, this study shows that an application of causality test on the time series of energy consumption and national output has masked a lot of information. The Toda-Yamamoto test with bootstrapped critical values and the newly proposed non-linear causality test reveal no causal relationship. However, a further application of these tests using series in different time-frequency domain obtained from wavelet decomposition indicates that while energy consumption Granger causes economic growth in the short run, the reverse is true in the medium term. A bidirectional causal relationship is found for the long run. This approach has proven to be superior in unveiling information on the energy-growth nexus that are useful for policy planning over different time horizons. PMID:29782534

6. The Relationship between Handedness and Mathematics Is Non-linear and Is Moderated by Gender, Age, and Type of Task

Sala, Giovanni; Signorelli, Michela; Barsuola, Giulia; Bolognese, Martina; Gobet, Fernand

2017-01-01

The relationship between handedness and mathematical ability is still highly controversial. While some researchers have claimed that left-handers are gifted in mathematics and strong right-handers perform the worst in mathematical tasks, others have more recently proposed that mixed-handers are the most disadvantaged group. However, the studies in the field differ with regard to the ages and the gender of the participants, and the type of mathematical ability assessed. To disentangle these discrepancies, we conducted five studies in several Italian schools (total participants: N = 2,314), involving students of different ages (six to seventeen) and a range of mathematical tasks (e.g., arithmetic and reasoning). The results show that (a) linear and quadratic functions are insufficient for capturing the link between handedness and mathematical ability; (b) the percentage of variance in mathematics scores explained by handedness was larger than in previous studies (between 3 and 10% vs. 1%), and (c) the effect of handedness on mathematical ability depended on age, type of mathematical tasks, and gender. In accordance with previous research, handedness does represent a correlate of achievement in mathematics, but the shape of this relationship is more complicated than has been argued so far. PMID:28649210

7. Relationship between rice yield and climate variables in southwest Nigeria using multiple linear regression and support vector machine analysis

Oguntunde, Philip G.; Lischeid, Gunnar; Dietrich, Ottfried

2018-03-01

This study examines the variations of climate variables and rice yield and quantifies the relationships among them using multiple linear regression, principal component analysis, and support vector machine (SVM) analysis in southwest Nigeria. The climate and yield data used was for a period of 36 years between 1980 and 2015. Similar to the observed decrease ( P 1 and explained 83.1% of the total variance of predictor variables. The SVM regression function using the scores of the first principal component explained about 75% of the variance in rice yield data and linear regression about 64%. SVM regression between annual solar radiation values and yield explained 67% of the variance. Only the first component of the principal component analysis (PCA) exhibited a clear long-term trend and sometimes short-term variance similar to that of rice yield. Short-term fluctuations of the scores of the PC1 are closely coupled to those of rice yield during the 1986-1993 and the 2006-2013 periods thereby revealing the inter-annual sensitivity of rice production to climate variability. Solar radiation stands out as the climate variable of highest influence on rice yield, and the influence was especially strong during monsoon and post-monsoon periods, which correspond to the vegetative, booting, flowering, and grain filling stages in the study area. The outcome is expected to provide more in-depth regional-specific climate-rice linkage for screening of better cultivars that can positively respond to future climate fluctuations as well as providing information that may help optimized planting dates for improved radiation use efficiency in the study area.

8. Non-Linear Relationships between Aflatoxin B1 Levels and the Biological Response of Monkey Kidney Vero Cells

Mendel Friedman

2013-08-01

Full Text Available Aflatoxin-producing fungi contaminate food and feed during pre-harvest, storage and processing periods. Once consumed, aflatoxins (AFs accumulate in tissues, causing illnesses in animals and humans. Most human exposure to AF seems to be a result of consumption of contaminated plant and animal products. The policy of blending and dilution of grain containing higher levels of aflatoxins with uncontaminated grains for use in animal feed implicitly assumes that the deleterious effects of low levels of the toxins are linearly correlated to concentration. This assumption may not be justified, since it involves extrapolation of these nontoxic levels in feed, which are not of further concern. To develop a better understanding of the significance of low dose effects, in the present study, we developed quantitative methods for the detection of biologically active aflatoxin B1 (AFB1 in Vero cells by two independent assays: the green fluorescent protein (GFP assay, as a measure of protein synthesis by the cells, and the microculture tetrazolium (MTT assay, as a measure of cell viability. The results demonstrate a non-linear dose-response relationship at the cellular level. AFB1 at low concentrations has an opposite biological effect to higher doses that inhibit protein synthesis. Additional studies showed that heat does not affect the stability of AFB1 in milk and that the Vero cell model can be used to determine the presence of bioactive AFB1 in spiked beef, lamb and turkey meat. The implication of the results for the cumulative effects of low amounts of AFB1 in numerous foods is discussed.

9. Relationship between rice yield and climate variables in southwest Nigeria using multiple linear regression and support vector machine analysis.

Oguntunde, Philip G; Lischeid, Gunnar; Dietrich, Ottfried

2018-03-01

This study examines the variations of climate variables and rice yield and quantifies the relationships among them using multiple linear regression, principal component analysis, and support vector machine (SVM) analysis in southwest Nigeria. The climate and yield data used was for a period of 36 years between 1980 and 2015. Similar to the observed decrease (P  1 and explained 83.1% of the total variance of predictor variables. The SVM regression function using the scores of the first principal component explained about 75% of the variance in rice yield data and linear regression about 64%. SVM regression between annual solar radiation values and yield explained 67% of the variance. Only the first component of the principal component analysis (PCA) exhibited a clear long-term trend and sometimes short-term variance similar to that of rice yield. Short-term fluctuations of the scores of the PC1 are closely coupled to those of rice yield during the 1986-1993 and the 2006-2013 periods thereby revealing the inter-annual sensitivity of rice production to climate variability. Solar radiation stands out as the climate variable of highest influence on rice yield, and the influence was especially strong during monsoon and post-monsoon periods, which correspond to the vegetative, booting, flowering, and grain filling stages in the study area. The outcome is expected to provide more in-depth regional-specific climate-rice linkage for screening of better cultivars that can positively respond to future climate fluctuations as well as providing information that may help optimized planting dates for improved radiation use efficiency in the study area.

10. The Parkinsonian Subthalamic Network: Measures of Power, Linear, and Non-linear Synchronization and their Relationship to L-DOPA Treatment and OFF State Motor Severity.

West, Timothy; Farmer, Simon; Berthouze, Luc; Jha, Ashwani; Beudel, Martijn; Foltynie, Thomas; Limousin, Patricia; Zrinzo, Ludvic; Brown, Peter; Litvak, Vladimir

2016-01-01

In this paper we investigated the dopaminergic modulation of neuronal interactions occurring in the subthalamic nucleus (STN) during Parkinson's disease (PD). We utilized linear measures of local and long range synchrony such as power and coherence, as well as Detrended Fluctuation Analysis for Phase Synchrony (DFA-PS)- a recently developed non-linear method that computes the extent of long tailed autocorrelations present in the phase interactions between two coupled signals. Through analysis of local field potentials (LFPs) taken from the STN we seek to determine changes in the neurodynamics that may underpin the pathophysiology of PD in a group of 12 patients who had undergone surgery for deep brain stimulation. We demonstrate up modulation of alpha-theta (5-12 Hz) band power in response to L-DOPA treatment, whilst low beta band power (15-20 Hz) band-power is suppressed. We also find evidence for significant local connectivity within the region surrounding STN although there was evidence for its modulation via administration of L-DOPA. Further to this we present evidence for a positive correlation between the phase ordering of bilateral STN interactions and the severity of bradykinetic and rigidity symptoms in PD. Although, the ability of non-linear measures to predict clinical state did not exceed standard measures such as beta power, these measures may help identify the connections which play a role in pathological dynamics.

11. Relationship between linear velocity and tangential push force while turning to change the direction of the manual wheelchair.

Hwang, Seonhong; Lin, Yen-Sheng; Hogaboom, Nathan S; Wang, Lin-Hwa; Koontz, Alicia M

2017-08-28

Wheelchair propulsion is a major cause of upper limb pain and injuries for manual wheelchair users with spinal cord injuries (SCIs). Few studies have investigated wheelchair turning biomechanics on natural ground surfaces. The purpose of this study was to investigate the relationship between tangential push force and linear velocity of the wheelchair during the turning portions of propulsion. Using an instrumented handrim, velocity and push force data were recorded for 25 subjects while they propel their own wheelchairs on a concrete floor along a figure-eight-shaped course at a maximum velocity. The braking force (1.03 N) of the inside wheel while turning was the largest of all other push forces (p<0.05). Larger changes in squared velocity while turning were significantly correlated with higher propulsive and braking forces used at the pre-turning, turning, and post-turning phases (p<0.05). Subjects with less change of velocity while turning needed less braking force to maneuver themselves successfully and safely around the turns. Considering the magnitude and direction of tangential force applied to the wheel, it seems that there are higher risks of injury and instability for upper limb joints when braking the inside wheel to turn. The results provide insight into wheelchair setup and mobility skills training for wheelchair users.

12. Evaluating the environmental fate of pharmaceuticals using a level III model based on poly-parameter linear free energy relationships

Zukowska, Barbara; Breivik, Knut; Wania, Frank

2006-01-01

We recently proposed how to expand the applicability of multimedia models towards polar organic chemicals by expressing environmental phase partitioning with the help of poly-parameter linear free energy relationships (PP-LFERs). Here we elaborate on this approach by applying it to three pharmaceutical substances. A PP-LFER-based version of a Level III fugacity model calculates overall persistence, concentrations and intermedia fluxes of polar and non-polar organic chemicals between air, water, soil and sediments at steady-state. Illustrative modeling results for the pharmaceuticals within a defined coastal region are presented and discussed. The model results are highly sensitive to the degradation rate in water and the equilibrium partitioning between organic carbon and water, suggesting that an accurate description of this particular partitioning equilibrium is essential in order to obtain reliable predictions of environmental fate. The PP-LFER based modeling approach furthermore illustrates that the greatest mobility in aqueous phases may be experienced by pharmaceuticals that combines a small molecular size with strong H-acceptor properties

13. Evaluating the environmental fate of pharmaceuticals using a level III model based on poly-parameter linear free energy relationships

Zukowska, Barbara [Department of Analytical Chemistry, Chemical Faculty, Gdansk University of Technology, 11/12 G. Narutowicza St., 80-952 Gdansk (Poland); Breivik, Knut [NILU- Norwegian Institute for Air Research, P.O. Box 100, NO-2027 Kjeller (Norway)]. E-mail: knut.breivik@nilu.no; Wania, Frank [Department of Physical and Environmental Sciences, University of Toronto at Scarborough, 1265 Military Trail, Scarborough, Ontario, M1C 1A4 (Canada)

2006-04-15

We recently proposed how to expand the applicability of multimedia models towards polar organic chemicals by expressing environmental phase partitioning with the help of poly-parameter linear free energy relationships (PP-LFERs). Here we elaborate on this approach by applying it to three pharmaceutical substances. A PP-LFER-based version of a Level III fugacity model calculates overall persistence, concentrations and intermedia fluxes of polar and non-polar organic chemicals between air, water, soil and sediments at steady-state. Illustrative modeling results for the pharmaceuticals within a defined coastal region are presented and discussed. The model results are highly sensitive to the degradation rate in water and the equilibrium partitioning between organic carbon and water, suggesting that an accurate description of this particular partitioning equilibrium is essential in order to obtain reliable predictions of environmental fate. The PP-LFER based modeling approach furthermore illustrates that the greatest mobility in aqueous phases may be experienced by pharmaceuticals that combines a small molecular size with strong H-acceptor properties.

14. Determination of polyparameter linear free energy relationship (pp-LFER) substance descriptors for established and alternative flame retardants.

Stenzel, Angelika; Goss, Kai-Uwe; Endo, Satoshi

2013-02-05

Polyparameter linear free energy relationships (pp-LFERs) can predict partition coefficients for a multitude of environmental and biological phases with high accuracy. In this work, the pp-LFER substance descriptors of 40 established and alternative flame retardants (e.g., polybrominated diphenyl ethers, hexabromocyclododecane, bromobenzenes, trialkyl phosphates) were determined experimentally. In total, 251 data for gas-chromatographic (GC) retention times and liquid/liquid partition coefficients (K) were measured and used to calibrate the pp-LFER substance descriptors. Substance descriptors were validated through a comparison between predicted and experimental log K for the systems octanol/water (K(ow)), water/air (K(wa)), organic carbon/water (K(oc)) and liposome/water (K(lipw)), revealing a high reliability of pp-LFER predictions based on our descriptors. For instance, the difference between predicted and experimental log K(ow) was <0.3 log units for 17 out of 21 compounds for which experimental values were available. Moreover, we found an indication that the H-bond acceptor value (B) depends on the solvent for some compounds. Thus, for predicting environmentally relevant partition coefficients it is important to determine B values using measurements in aqueous systems. The pp-LFER descriptors calibrated in this study can be used to predict partition coefficients for which experimental data are unavailable, and the predicted values can serve as references for further experimental measurements.

15. Linear free energy relationships between aqueous phase hydroxyl radical reaction rate constants and free energy of activation.

Minakata, Daisuke; Crittenden, John

2011-04-15

The hydroxyl radical (HO(•)) is a strong oxidant that reacts with electron-rich sites on organic compounds and initiates complex radical chain reactions in aqueous phase advanced oxidation processes (AOPs). Computer based kinetic modeling requires a reaction pathway generator and predictions of associated reaction rate constants. Previously, we reported a reaction pathway generator that can enumerate the most important elementary reactions for aliphatic compounds. For the reaction rate constant predictor, we develop linear free energy relationships (LFERs) between aqueous phase literature-reported HO(•) reaction rate constants and theoretically calculated free energies of activation for H-atom abstraction from a C-H bond and HO(•) addition to alkenes. The theoretical method uses ab initio quantum mechanical calculations, Gaussian 1-3, for gas phase reactions and a solvation method, COSMO-RS theory, to estimate the impact of water. Theoretically calculated free energies of activation are found to be within approximately ±3 kcal/mol of experimental values. Considering errors that arise from quantum mechanical calculations and experiments, this should be within the acceptable errors. The established LFERs are used to predict the HO(•) reaction rate constants within a factor of 5 from the experimental values. This approach may be applied to other reaction mechanisms to establish a library of rate constant predictions for kinetic modeling of AOPs.

16. Development of polyparameter linear free energy relationship models for octanol-air partition coefficients of diverse chemicals.

Jin, Xiaochen; Fu, Zhiqiang; Li, Xuehua; Chen, Jingwen

2017-03-22

The octanol-air partition coefficient (K OA ) is a key parameter describing the partition behavior of organic chemicals between air and environmental organic phases. As the experimental determination of K OA is costly, time-consuming and sometimes limited by the availability of authentic chemical standards for the compounds to be determined, it becomes necessary to develop credible predictive models for K OA . In this study, a polyparameter linear free energy relationship (pp-LFER) model for predicting K OA at 298.15 K and a novel model incorporating pp-LFERs with temperature (pp-LFER-T model) were developed from 795 log K OA values for 367 chemicals at different temperatures (263.15-323.15 K), and were evaluated with the OECD guidelines on QSAR model validation and applicability domain description. Statistical results show that both models are well-fitted, robust and have good predictive capabilities. Particularly, the pp-LFER model shows a strong predictive ability for polyfluoroalkyl substances and organosilicon compounds, and the pp-LFER-T model maintains a high predictive accuracy within a wide temperature range (263.15-323.15 K).

17. 2D Quantitative Structure-Property Relationship Study of Mycotoxins by Multiple Linear Regression and Support Vector Machine

Fereshteh Shiri

2010-08-01

Full Text Available In the present work, support vector machines (SVMs and multiple linear regression (MLR techniques were used for quantitative structure–property relationship (QSPR studies of retention time (tR in standardized liquid chromatography–UV–mass spectrometry of 67 mycotoxins (aflatoxins, trichothecenes, roquefortines and ochratoxins based on molecular descriptors calculated from the optimized 3D structures. By applying missing value, zero and multicollinearity tests with a cutoff value of 0.95, and genetic algorithm method of variable selection, the most relevant descriptors were selected to build QSPR models. MLRand SVMs methods were employed to build QSPR models. The robustness of the QSPR models was characterized by the statistical validation and applicability domain (AD. The prediction results from the MLR and SVM models are in good agreement with the experimental values. The correlation and predictability measure by r2 and q2 are 0.931 and 0.932, repectively, for SVM and 0.923 and 0.915, respectively, for MLR. The applicability domain of the model was investigated using William’s plot. The effects of different descriptors on the retention times are described.

18. A non-linear relationship between the cumulative exposure to occupational stressors and nurses' burnout and the potentially emotion regulation factors.

Sun, Ji-Wei; Lin, Ping-Zhen; Zhang, Hui-Hui; Li, Jia-Huan; Cao, Feng-Lin

2017-10-08

Stressful situations can increase the likelihood of nurses experiencing negative emotions, especially burnout. To explore the association of cumulative exposure to occupational stressors and emotion regulation strategies with nurses' burnout. Participants were 602 nurses from three general hospitals in Jinan, China. Social demographic characteristics, occupational stress, burnout, and emotion regulation strategies (cognitive reappraisal, expressive suppression, and rumination), were assessed. Nearly 70% of nurses reported that they were burnt out. Those with a moderate level and high level of stressors were 3.203 times and 26.444 times more likely to have burnout, respectively (x 2 trend = 62.732). Logistic regression revealed that nurses had higher cognitive reappraisal score (odds ratios (OR) = 0.941), scored lower for burnout. Those who had higher expressive suppression score (OR = 1.054), higher rumination score (OR = 1.037), and a higher level of stressors (OR = 2.779-18.259) scored higher for burnout. The results of sensitivity analysis were similar. A non-linear relationship exists between the cumulative exposure to occupational stressors and nurses' burnout. Those who less frequently use cognitive reappraisal, more frequently use rumination and expressive suppression, and have a high level of stressors may be more likely to experience burnout.

19. The symbiotic relationship between dominant canopy trees and soil microbes affects the nitrogen source utilization of co-existing understory trees

Iwaoka, C.; Hyodo, F.; Taniguchi, T.; Shi, W.; Du, S.; Yamanaka, N.; Tateno, R.

2017-12-01

The symbiotic relationship between dominant canopy trees and soil microbes such as mycorrhiza or nitrogen (N) fixer are important determinants of soil N dynamics of a forest. However, it is not known how and to what extent the symbiotic relationship of dominant canopy trees with soil microbes affect the N source of co-existing trees in forest. We measured the δ15N of surface soils (0-10 cm), leaves, and roots of the dominant canopy trees and common understory trees in an arbuscular mycorrhizal N-fixing black locust (Robinia pseudoacacia) plantation and an ectomycorrhizal oak (Quercus liaotungensis) natural forest in a China dryland. We also analyzed the soil dissolved N content in soil extracts and absorbed by ion exchange resin, and soil ammonia-oxidizer abundance using real-time PCR. The δ15N of soil and leaves were higher in the black locust forest than in the oak forest, although the δ15N of fine roots was similar in the two forests, in co-existing understory trees as well as dominant canopy trees. Accordingly, the δ15N of leaves was similar to or higher than that of fine roots in the black locust forest, whereas it was consistently lower than that of fine roots in the oak forest. In the black locust forest, the soil dissolved organic N and ammonium N contents were less abundant but the nitrate N contents in soils and absorbed by the ion exchange resin and ammonia-oxidizer abundance were greater, due to N fixation or less uptake of organic N from arbuscular mycorrhiza. In contrast, the soil dissolved organic N and ammonium N contents were more abundant in the oak forest, whereas the N content featured very low nitrate, due to ectomycorrhizal ability to access organic N. These results suggest that the main N source is nitrate N in the black locust forest, but dissolved organic N or ammonium N in the oak forest. N fixation or high N loss due to high N availability would cause high δ15N in soil and leaves in black locust forest. On the other hand, low soil N

20. Real time relationship between individual finger force and grip exertion on distal phalanges in linear force following tasks.

Luo, Shi-Jian; Shu, Ge; Gong, Yan

2018-05-01

1. Pre-existing oblique transfer zones and transfer/transform relationships in continental margins: New insights from the southeastern Gulf of Aden, Socotra Island, Yemen

Bellahsen, N.; Leroy, S.; Autin, J.; Razin, P.; d'Acremont, E.; Sloan, H.; Pik, R.; Ahmed, A.; Khanbari, K.

2013-11-01

Transfer zones are ubiquitous features in continental rifts and margins, as are transform faults in oceanic lithosphere. Here, we present a structural study of the Hadibo Transfer Zone (HTZ), located in Socotra Island (Yemen) in the southeastern Gulf of Aden. There, we interpret this continental transfer fault zone to represent a reactivated pre-existing structure. Its trend is oblique to the direction of divergence and it has been active from the early up to the latest stages of rifting. One of the main oceanic fracture zones (FZ), the Hadibo-Sharbithat FZ, is aligned with and appears to be an extension of the HTZ and is probably genetically linked to it. Comparing this setting with observations from other Afro-Arabian rifts as well as with passive margins worldwide, it appears that many continental transfer zones are reactivated pre-existing structures, oblique to divergence. We therefore establish a classification system for oceanic FZ based upon their relationship with syn-rift structures. Type 1 FZ form at syn-rift structures and are late syn-rift to early syn-OCT. Type 2 FZ form during the OCT formation and Type 3 FZ form within the oceanic domain, after the oceanic spreading onset. The latter are controlled by far-field forces, magmatic processes, spreading rates, and oceanic crust rheology.

2. LINEAR SOLVATION ENERGY RELATIONSHIPS FOR CHARACTERIZATION OF MLC SYSTEMS WITH SODIUM DODECYL SULPHATE MOBILE PHASES MODIFIED BY ALIPHATIC ALCOHOLS OR CARBOXYLIC ACIDS

Markov, Vadym V.; Boichenko, Alexander P.; Loginova, Lidia P.

2012-01-01

The Linear Solvation Energy Relationships (LSER) have been successfully used for the modeling of partition and retention of the set of test compounds in different systems. The properties of micellar chromatographic systems with the mobile phases on the basis of sodium dodecylsulphate modified (ODS)

3. Comparing Linear Relationships between E-Book Usage and University Student and Faculty Populations: The Differences between E-Reference and E-Monograph Collections

Lamothe, Alain R.

2013-01-01

This paper reports the results from a quantitative study examining the strength of linear relationships between Laurentian University students and faculty members and the J. N. Desmarais Library's reference and monograph e-book collections. The number of full-text items accessed, searches performed, and undergraduate, graduate, and faculty…

4. Relationship Between the Parameters of the Linear and Nonlinear Wave Generation Stages in a Magnetospheric Cyclotron Maser in the Backward-Wave Oscillator Regime

Demekhov, A. G.

2017-03-01

By using numerical simulations we generalize certain relationships between the parameters of quasimonochromatic whistler-mode waves generated at the linear and nonlinear stages of the cyclotron instability in the backward-wave oscillator regime. One of these relationships is between the wave amplitude at the nonlinear stage and the linear growth rate of the cyclotron instability. It was obtained analytically by V.Yu.Trakhtengerts (1984) for a uniform medium under the assumption of constant frequency and amplitude of the generated wave. We show that a similar relationship also holds for the signals generated in a nonuniform magnetic field and having a discrete structure in the form of short wave packets (elements) with fast frequency drift inside each element. We also generalize the formula for the linear growth rate of absolute cyclotron instability in a nonuniform medium and analyze the relationship between the frequency drift rate in the discrete elements and the wave amplitude. These relationships are important for analyzing the links between the parameters of chorus emissions in the Earth's and planetary magnetospheres and the characteristics of the energetic charged particles generating these signals.

5. Existence of a miscibility gap in the U-Nd-O ternary system and its relationship with the HBS of irradiated nuclear fuel

Dottavio, Giannina

2014-01-01

: cationic fission products actinides or lanthanides). In order to investigate this hypothesis we have characterized by XRD different irradiated fuels as a function of lanthanides and actinides content and the O/M ratio. The results obtained are consistent with the hypothesis formulated. These last results lead us to reconsider the evolution of irradiated fuel as a function of the existence of a miscibility gap. From this perspective, we propose a relationship between the existence of the miscibility gap and the formation of the so-called high burnup structures which appears in the nuclear fuel for local burnups higher than 60 GWj/t. (author) [fr

6. Organic Carbon/Water and Dissolved Organic Carbon/Water Partitioning of Cyclic Volatile Methylsiloxanes: Measurements and Polyparameter Linear Free Energy Relationships.

Panagopoulos, Dimitri; Jahnke, Annika; Kierkegaard, Amelie; MacLeod, Matthew

2015-10-20

The sorption of cyclic volatile methyl siloxanes (cVMS) to organic matter has a strong influence on their fate in the aquatic environment. We report new measurements of the partition ratios between freshwater sediment organic carbon and water (KOC) and between Aldrich humic acid dissolved organic carbon and water (KDOC) for three cVMS, and for three polychlorinated biphenyls (PCBs) that were used as reference chemicals. Our measurements were made using a purge-and-trap method that employs benchmark chemicals to calibrate mass transfer at the air/water interface in a fugacity-based multimedia model. The measured log KOC of octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and dodecamethylcyclohexasiloxane (D6) were 5.06, 6.12, and 7.07, and log KDOC were 5.05, 6.13, and 6.79. To our knowledge, our measurements for KOC of D6 and KDOC of D4 and D6 are the first reported. Polyparameter linear free energy relationships (PP-LFERs) derived from training sets of empirical data that did not include cVMS generally did not predict our measured partition ratios of cVMS accurately (root-mean-squared-error (RMSE) for logKOC 0.76 and for logKDOC 0.73). We constructed new PP-LFERs that accurately describe partition ratios for the cVMS as well as for other chemicals by including our new measurements in the existing training sets (logKOC RMSEcVMS: 0.09, logKDOC RMSEcVMS: 0.12). The PP-LFERs we have developed here should be further evaluated and perhaps recalibrated when experimental data for other siloxanes become available.

7. Genetic parameters of linear conformation type traits and their relationship with milk yield throughout lactation in mixed-breed dairy goats.

McLaren, A; Mucha, S; Mrode, R; Coffey, M; Conington, J

2016-07-01

Conformation traits are of interest to many dairy goat breeders not only as descriptive traits in their own right, but also because of their influence on production, longevity, and profitability. If these traits are to be considered for inclusion in future dairy goat breeding programs, relationships between them and production traits such as milk yield must be considered. With the increased use of regression models to estimate genetic parameters, an opportunity now exists to investigate correlations between conformation traits and milk yield throughout lactation in more detail. The aims of this study were therefore to (1) estimate genetic parameters for conformation traits in a population of crossbred dairy goats, (2) estimate correlations between all conformation traits, and (3) assess the relationship between conformation traits and milk yield throughout lactation. No information on milk composition was available. Data were collected from goats based on 2 commercial goat farms during August and September in 2013 and 2014. Ten conformation traits, relating to udder, teat, leg, and feet characteristics, were scored on a linear scale (1-9). The overall data set comprised data available for 4,229 goats, all in their first lactation. The population of goats used in the study was created using random crossings between 3 breeds: British Alpine, Saanen, and Toggenburg. In each generation, the best performing animals were selected for breeding, leading to the formation of a synthetic breed. The pedigree file used in the analyses contained sire and dam information for a total of 30,139 individuals. The models fitted relevant fixed and random effects. Heritability estimates for the conformation traits were low to moderate, ranging from 0.02 to 0.38. A range of positive and negative phenotypic and genetic correlations between the traits were observed, with the highest correlations found between udder depth and udder attachment (0.78), teat angle and teat placement (0

8. The Multiple Correspondence Analysis Method and Brain Functional Connectivity: Its Application to the Study of the Non-linear Relationships of Motor Cortex and Basal Ganglia.

Rodriguez-Sabate, Clara; Morales, Ingrid; Sanchez, Alberto; Rodriguez, Manuel

2017-01-01

The complexity of basal ganglia (BG) interactions is often condensed into simple models mainly based on animal data and that present BG in closed-loop cortico-subcortical circuits of excitatory/inhibitory pathways which analyze the incoming cortical data and return the processed information to the cortex. This study was aimed at identifying functional relationships in the BG motor-loop of 24 healthy-subjects who provided written, informed consent and whose BOLD-activity was recorded by MRI methods. The analysis of the functional interaction between these centers by correlation techniques and multiple linear regression showed non-linear relationships which cannot be suitably addressed with these methods. The multiple correspondence analysis (MCA), an unsupervised multivariable procedure which can identify non-linear interactions, was used to study the functional connectivity of BG when subjects were at rest. Linear methods showed different functional interactions expected according to current BG models. MCA showed additional functional interactions which were not evident when using lineal methods. Seven functional configurations of BG were identified with MCA, two involving the primary motor and somatosensory cortex, one involving the deepest BG (external-internal globus pallidum, subthalamic nucleus and substantia nigral), one with the input-output BG centers (putamen and motor thalamus), two linking the input-output centers with other BG (external pallidum and subthalamic nucleus), and one linking the external pallidum and the substantia nigral. The results provide evidence that the non-linear MCA and linear methods are complementary and should be best used in conjunction to more fully understand the nature of functional connectivity of brain centers.

9. Reliability of the Load-Velocity Relationship Obtained Through Linear and Polynomial Regression Models to Predict the One-Repetition Maximum Load.

Pestaña-Melero, Francisco Luis; Haff, G Gregory; Rojas, Francisco Javier; Pérez-Castilla, Alejandro; García-Ramos, Amador

2017-12-18

This study aimed to compare the between-session reliability of the load-velocity relationship between (1) linear vs. polynomial regression models, (2) concentric-only vs. eccentric-concentric bench press variants, as well as (3) the within-participants vs. the between-participants variability of the velocity attained at each percentage of the one-repetition maximum (%1RM). The load-velocity relationship of 30 men (age: 21.2±3.8 y; height: 1.78±0.07 m, body mass: 72.3±7.3 kg; bench press 1RM: 78.8±13.2 kg) were evaluated by means of linear and polynomial regression models in the concentric-only and eccentric-concentric bench press variants in a Smith Machine. Two sessions were performed with each bench press variant. The main findings were: (1) first-order-polynomials (CV: 4.39%-4.70%) provided the load-velocity relationship with higher reliability than second-order-polynomials (CV: 4.68%-5.04%); (2) the reliability of the load-velocity relationship did not differ between the concentric-only and eccentric-concentric bench press variants; (3) the within-participants variability of the velocity attained at each %1RM was markedly lower than the between-participants variability. Taken together, these results highlight that, regardless of the bench press variant considered, the individual determination of the load-velocity relationship by a linear regression model could be recommended to monitor and prescribe the relative load in the Smith machine bench press exercise.

10. New Equating Methods and Their Relationships with Levine Observed Score Linear Equating under the Kernel Equating Framework

Chen, Haiwen; Holland, Paul

2010-01-01

In this paper, we develop a new curvilinear equating for the nonequivalent groups with anchor test (NEAT) design under the assumption of the classical test theory model, that we name curvilinear Levine observed score equating. In fact, by applying both the kernel equating framework and the mean preserving linear transformation of…

11. THE EVALUATION OF THE RELATIONSHIP LEVEL BETWEEN HUMAN RESOURCES MANAGERS AND LINEAR MANAGERS REGARDING PERSONNEL MANAGEMENT IN THE ORGANIZATIONS FROM THE REPUBLIC OF MOLDOVA

BÎRCĂ ALIC

2017-11-01

Full Text Available This scientific approach refers to the relationship between the managers of human resources and linear managers on personnel management within the organization. In this context it is shown the importance of cooperation between the human resources managers and the linear managers on achieving the organizational performance.It is shown the degree of involvement of both the division of human resources and the linear and functional managers and in solving the problems of employees, but also in the implementation of different methods and procedure for the human resources. Also, in the case of the line and the functional managers, is important awareness of the need for their involvement in the activities related to the human resources management. Also, there are shown the possible risks that might face the organization in the case of a mismanagement of human resources management from the linear managers. In order to assess the level of networking of human resources managers with the linear managers and the functional organisations of the Republic of Moldova has been applied the sociological method-questionnaire, being used Likert scale.

12. Existence theory in optimal control

Olech, C.

1976-01-01

This paper treats the existence problem in two main cases. One case is that of linear systems when existence is based on closedness or compactness of the reachable set and the other, non-linear case refers to a situation where for the existence of optimal solutions closedness of the set of admissible solutions is needed. Some results from convex analysis are included in the paper. (author)

13. Linear regression

Olive, David J

2017-01-01

This text covers both multiple linear regression and some experimental design models. The text uses the response plot to visualize the model and to detect outliers, does not assume that the error distribution has a known parametric distribution, develops prediction intervals that work when the error distribution is unknown, suggests bootstrap hypothesis tests that may be useful for inference after variable selection, and develops prediction regions and large sample theory for the multivariate linear regression model that has m response variables. A relationship between multivariate prediction regions and confidence regions provides a simple way to bootstrap confidence regions. These confidence regions often provide a practical method for testing hypotheses. There is also a chapter on generalized linear models and generalized additive models. There are many R functions to produce response and residual plots, to simulate prediction intervals and hypothesis tests, to detect outliers, and to choose response trans...

14. A relação professor-aluno não existe: corpo e imagem, presença e distância/The relationship teacher-student does not exist: body, image, presence and distance

Rinaldo Voltolini

2007-01-01

Full Text Available O recente e crescente uso de recursos áudio-visuais e de informática no ensino recolocou para muitos a questão da necessidade da presença do professor. Longe de ser apenas um recurso que vem prolongar o que já está no universo escolar, sua entrada modifica a dinâmica da relação professor-aluno. As condições que permitiram esta entrada parecem corresponder aquilo que Lacan elucida em sua teoria dos Discursos quando se pergunta: os gadgets vencerão? A mudança das relações entre o sujeito e o objeto, características deste novo discurso contemporâneo, o do Capitalista, no qual o objeto parece predominar sobre o sujeito, podem ser lidas em vários âmbitos. O objetivo deste estudo é analisar as vicissitudes desta mudança no interior das práticas educativas, particularmente em torno do que esta questão sobre a necessidade da presença do professor ilustra sobre ela. The recent and growing use of audiovisual sources and computing in teaching re-set for many people the issue of the need of the teacher’s presence. Far from being only a source that extends what already is in the school universe, its entrance changes the dynamic of the relationship teacher-student. The circumstances which permitted this entrance seem to correspond to what Lacan elucidates in his theory of the Discourses when it is questioned: will the gadgets win? The change of relationship between subject and object, typical of this new contemporary discourse, the Capitalist, in which the object seems to predominate the subject may be understood in various ways. The goal of this study is to analyze the vicissitudes of this change inside the educational practice, particularly considering what this question of the necessity of the teacher’s presence illustrates about it.

15. The Relationship between a Linear Combination of Intelligence, Musical Background, Rhythm Ability and Tapping Ability to Typewriting Speed and Accuracy.

Fante, Cheryl H.

This study was conducted in an attempt to identify any predictor or combination of predictors of a beginning typewriting student's success. Variables of intelligence, rhythmic ability, musical background, and tapping ability were combined to study their relationship to typewriting speed and accuracy. A sample of 109 high school students was…

16. A non-linear beta-binomial regression model for mapping EORTC QLQ- C30 to the EQ-5D-3L in lung cancer patients: a comparison with existing approaches.

Khan, Iftekhar; Morris, Stephen

2014-11-12

The performance of the Beta Binomial (BB) model is compared with several existing models for mapping the EORTC QLQ-C30 (QLQ-C30) on to the EQ-5D-3L using data from lung cancer trials. Data from 2 separate non small cell lung cancer clinical trials (TOPICAL and SOCCAR) are used to develop and validate the BB model. Comparisons with Linear, TOBIT, Quantile, Quadratic and CLAD models are carried out. The mean prediction error, R(2), proportion predicted outside the valid range, clinical interpretation of coefficients, model fit and estimation of Quality Adjusted Life Years (QALY) are reported and compared. Monte-Carlo simulation is also used. The Beta-Binomial regression model performed 'best' among all models. For TOPICAL and SOCCAR trials, respectively, residual mean square error (RMSE) was 0.09 and 0.11; R(2) was 0.75 and 0.71; observed vs. predicted means were 0.612 vs. 0.608 and 0.750 vs. 0.749. Mean difference in QALY's (observed vs. predicted) were 0.051 vs. 0.053 and 0.164 vs. 0.162 for TOPICAL and SOCCAR respectively. Models tested on independent data show simulated 95% confidence from the BB model containing the observed mean more often (77% and 59% for TOPICAL and SOCCAR respectively) compared to the other models. All algorithms over-predict at poorer health states but the BB model was relatively better, particularly for the SOCCAR data. The BB model may offer superior predictive properties amongst mapping algorithms considered and may be more useful when predicting EQ-5D-3L at poorer health states. We recommend the algorithm derived from the TOPICAL data due to better predictive properties and less uncertainty.

17. Study on a linear relationship between limited pressure difference and coil current of on/off valve and its influential factors.

Zhang, Junzhi; Lv, Chen; Yue, Xiaowei; Li, Yutong; Yuan, Ye

2014-01-01

On/off solenoid valves with PWM control are widely used in all types of vehicle electro-hydraulic control systems respecting to their desirable properties of reliable, low cost and fast acting. However, it can hardly achieve a linear hydraulic modulation by using on/off valves mainly due to the nonlinear behaviors of valve dynamics and fluid, which affects the control accuracy significantly. In this paper, a linear relationship between limited pressure difference and coil current of an on/off valve in its critical closed state is proposed and illustrated, which has a great potential to be applied to improve hydraulic control performance. The hydraulic braking system of case study is modeled. The linear correspondence between limited pressure difference and coil current of the inlet valve is simulated and further verified experimentally. Based on validated simulation models, the impacts of key parameters are researched. The limited pressure difference affected by environmental temperatures is experimentally studied, and the amended linear relation is given according to the test data. © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

18. Constant post-irradiation repopulation rates and linear relationship between cellular blood response and number of transplanted bone marrow cells in inbread mice

Petersen, B.H.

1977-01-01

Graded doses of syngeneic bone marrow cells were transplanted into lethally irradiated mice. Repopulation curves of peripheral blood granulocytes and platelets were apparently exponential and parallel after doses larger than 5 x 10 5 cells. The blood platelet sub(d) was reduced from 111 h to 53-57 h, and granulocyte Tsub(d) from 57 to 40 h in transplanted groups. The mean blood cell counts were reproducible to be used as a biological assay of the amount of bone marrow cells transplanted. Linear relationship between increment of blood cells up to day 16 and number of bone marrow cells transplanted on day 1 was demonstrated (1,200 granulocytes and 14,300 platelets/μl blood per 10 5 bone marrow cells). The linearity suggested a mean Tsub(d) < 22.5 h of proliferating bone marrow cells, and allowed a rough estimation of mouse bone marrow stem cell radiosensitivity (Dsub(o) 76 rad). (author)

19. Linear mixed-effects models to describe length-weight relationships for yellow croaker (Larimichthys Polyactis) along the north coast of China.

Ma, Qiuyun; Jiao, Yan; Ren, Yiping

2017-01-01

In this study, length-weight relationships and relative condition factors were analyzed for Yellow Croaker (Larimichthys polyactis) along the north coast of China. Data covered six regions from north to south: Yellow River Estuary, Coastal Waters of Northern Shandong, Jiaozhou Bay, Coastal Waters of Qingdao, Haizhou Bay, and South Yellow Sea. In total 3,275 individuals were collected during six years (2008, 2011-2015). One generalized linear model, two simply linear models and nine linear mixed effect models that applied the effects from regions and/or years to coefficient a and/or the exponent b were studied and compared. Among these twelve models, the linear mixed effect model with random effects from both regions and years fit the data best, with lowest Akaike information criterion value and mean absolute error. In this model, the estimated a was 0.0192, with 95% confidence interval 0.0178~0.0308, and the estimated exponent b was 2.917 with 95% confidence interval 2.731~2.945. Estimates for a and b with the random effects in intercept and coefficient from Region and Year, ranged from 0.013 to 0.023 and from 2.835 to 3.017, respectively. Both regions and years had effects on parameters a and b, while the effects from years were shown to be much larger than those from regions. Except for Coastal Waters of Northern Shandong, a decreased from north to south. Condition factors relative to reference years of 1960, 1986, 2005, 2007, 2008~2009 and 2010 revealed that the body shape of Yellow Croaker became thinner in recent years. Furthermore relative condition factors varied among months, years, regions and length. The values of a and relative condition factors decreased, when the environmental pollution became worse, therefore, length-weight relationships could be an indicator for the environment quality. Results from this study provided basic description of current condition of Yellow Croaker along the north coast of China.

20. Use of linear free energy relationship to predict Gibbs free energies of formation of pyrochlore phases (CaMTi2O7)

Xu, H.; Wang, Y.

1999-01-01

In this letter, a linear free energy relationship is used to predict the Gibbs free energies of formation of crystalline phases of pyrochlore and zirconolite families with stoichiometry of MCaTi 2 O 7 (or, CaMTi 2 O 7 ,) from the known thermodynamic properties of aqueous tetravalent cations (M 4+ ). The linear free energy relationship for tetravalent cations is expressed as ΔG f,M v X 0 =a M v X ΔG n,M 4+ 0 +b M v X +β M v X r M 4+ , where the coefficients a M v X , b M v X , and β M v X characterize a particular structural family of M v X, r M 4+ is the ionic radius of M 4+ cation, ΔG f,M v X 0 is the standard Gibbs free energy of formation of M v X, and ΔG n,M 4+ 0 is the standard non-solvation energy of cation M 4+ . The coefficients for the structural family of zirconolite with the stoichiometry of M 4+ CaTi 2 O 7 are estimated to be: a M v X =0.5717, b M v X =-4284.67 (kJ/mol), and β M v X =27.2 (kJ/mol nm). The coefficients for the structural family of pyrochlore with the stoichiometry of M 4+ CaTi 2 O 7 are estimated to be: a M v X =0.5717, b M v X =-4174.25 (kJ/mol), and β M v X =13.4 (kJ/mol nm). Using the linear free energy relationship, the Gibbs free energies of formation of various zirconolite and pyrochlore phases are calculated. (orig.)

1. Determining Whether a Definitive Causal Relationship Exists Between Aripiprazole and Tardive Dyskinesia and/or Dystonia in Patients With Major Depressive Disorder, Part 3: Clinical Trial Data.

Preskorn, Sheldon H; Macaluso, Matthew

2016-03-01

three, 14-week studies involving 1088 subjects, 409 of whom were elderly like the 76-year-old individual presented in the case in the first column of this series. Finally, 3 short-term studies evaluated the use of aripiprazole in patients with psychosis associated with Alzheimer disease, a population who would be considered a relatively higher risk group for developing TD when exposed to antipsychotics and that also closely matches the patient in the case presented at the beginning of this series in terms of age. No incidence of TD was reported in this sample and mean scores on the Abnormal Involuntary Movement Scale decreased in individuals exposed to aripiprazole compared with those on placebo. On the basis of results of this review and data from registration trials of aripiprazole for all indications, the potential (or raw) incidence of what was termed TD occurred at rates ranging from 0.004 (4/987) based on long-term safety data from the program investigating aripiprazole augmentation treatment in MDD, to 0.0016 (19/11,897) based on the total safety database from aripiprazole registration trials for all indications, to 0 in trials in elderly individuals with Alzheimer disease. The confidence intervals for all of these potential incidence rates overlap with zero. The next column in this 5-part series reviews 37 case reports that reported TD in association with aripiprazole treatment and 27 case reports that suggested an improvement in preexisting TD with aripiprazole treatment. The fifth and final column in this series will discuss the types of prohibitively expensive and logistically difficult studies that would be needed to determine whether a definitive causal relationship between aripiprazole and TD exists.

2. A linear relationship between wave power and erosion determines salt-marsh resilience to violent storms and hurricanes

Leonardi, Nicoletta; Ganju, Neil K.; Fagherazzi, Sergio

2016-01-01

Salt marsh losses have been documented worldwide because of land use change, wave erosion, and sea-level rise. It is still unclear how resistant salt marshes are to extreme storms and whether they can survive multiple events without collapsing. Based on a large dataset of salt marsh lateral erosion rates collected around the world, here, we determine the general response of salt marsh boundaries to wave action under normal and extreme weather conditions. As wave energy increases, salt marsh response to wind waves remains linear, and there is not a critical threshold in wave energy above which salt marsh erosion drastically accelerates. We apply our general formulation for salt marsh erosion to historical wave climates at eight salt marsh locations affected by hurricanes in the United States. Based on the analysis of two decades of data, we find that violent storms and hurricanes contribute less than 1% to long-term salt marsh erosion rates. In contrast, moderate storms with a return period of 2.5 mo are those causing the most salt marsh deterioration. Therefore, salt marshes seem more susceptible to variations in mean wave energy rather than changes in the extremes. The intrinsic resistance of salt marshes to violent storms and their predictable erosion rates during moderate events should be taken into account by coastal managers in restoration projects and risk management plans.

3. A linear relationship between wave power and erosion determines salt-marsh resilience to violent storms and hurricanes.

Leonardi, Nicoletta; Ganju, Neil K; Fagherazzi, Sergio

2016-01-05

Salt marsh losses have been documented worldwide because of land use change, wave erosion, and sea-level rise. It is still unclear how resistant salt marshes are to extreme storms and whether they can survive multiple events without collapsing. Based on a large dataset of salt marsh lateral erosion rates collected around the world, here, we determine the general response of salt marsh boundaries to wave action under normal and extreme weather conditions. As wave energy increases, salt marsh response to wind waves remains linear, and there is not a critical threshold in wave energy above which salt marsh erosion drastically accelerates. We apply our general formulation for salt marsh erosion to historical wave climates at eight salt marsh locations affected by hurricanes in the United States. Based on the analysis of two decades of data, we find that violent storms and hurricanes contribute less than 1% to long-term salt marsh erosion rates. In contrast, moderate storms with a return period of 2.5 mo are those causing the most salt marsh deterioration. Therefore, salt marshes seem more susceptible to variations in mean wave energy rather than changes in the extremes. The intrinsic resistance of salt marshes to violent storms and their predictable erosion rates during moderate events should be taken into account by coastal managers in restoration projects and risk management plans.

4. Prolificacy and Its Relationship with Age, Body Weight, Parity, Previous Litter Size and Body Linear Type Traits in Meat-type Goats

Avijit Haldar

2014-05-01

Full Text Available Data on age and body weight at breeding, parity, previous litter size, days open and some descriptive body linear traits from 389 meat-type, prolific Black Bengal goats in Tripura State of India, were collected for 3 and 1/2 years (2007 to 2010 and analyzed using logistic regression model. The objectives of the study were i to evaluate the effect of age and body weight at breeding, parity, previous litter size and days open on litter size of does; and ii to investigate if body linear type traits influenced litter size in meat-type, prolific goats. The incidence of 68.39% multiple births with a prolificacy rate of 175.07% was recorded. Higher age (>2.69 year, higher parity order (>2.31, more body weight at breeding (>20.5 kg and larger previous litter size (>1.65 showed an increase likelihood of multiple litter size when compared to single litter size. There was a strong, positive relationship between litter size and various body linear type traits like neck length (>22.78 cm, body length (>54.86 cm, withers height (>48.85 cm, croup height (>50.67 cm, distance between tuber coxae bones (>11.38 cm and distance between tuber ischii bones (>4.56 cm for discriminating the goats bearing multiple fetuses from those bearing a single fetus.

5. Studies on the retention mechanism of solutes in hydrophilic interaction chromatography using stoichiometric displacement theory I. The linear relationship of lgk' vs. lg[H2O].

Wang, Fei; Yang, Fan; Tian, Yang; Liu, Jiawei; Shen, Jiwei; Bai, Quan

2018-01-01

A stoichiometric displacement model for retention (SDM-R) of small solutes and proteins based on hydrophilic interaction chromatography (HILIC) was presented. A linear equation that related the logarithm of the capacity factor of the solute to the logarithm of the concentration of water in the mobile phase was derived. The stoichiometric displacement parameters, Z (the number of water molecules required to displace a solute from ligands) and lgI (containing a number of constants that relate to the affinity of solute to the ligands) could be obtained from the slope and the intercept of the linear plots of lgk' vs. lg[H 2 O]. The retention behaviors and retention mechanism of 15 kinds of small solutes and 6 kinds of proteins on 5 kinds HILIC columns with different ligands were investigated with SDM-R in typical range of water concentration in mobile phase. A good linear relationship between lgk' and lg[H 2 O] demonstrated that the most rational retention mechanism of solute in HILIC was a stoichiometric displacement process between solute and solvent molecules with water as displacing agents, which was not only valid for small solutes, but also could be used to explain the retention mechanism of biopolymers in HILIC. Comparing with the partition and adsorption models in HILIC, SDM-R was superior to them. Copyright © 2017 Elsevier B.V. All rights reserved.

6. Endurance training decreases the non-linearity in the oxygen uptake-power output relationship in humans.

Majerczak, Joanna; Korostynski, Michal; Nieckarz, Zenon; Szkutnik, Zbigniew; Duda, Krzysztof; Zoladz, Jerzy A

2012-03-01

In this study, we hypothesized that 5 weeks of cycling endurance training can decrease the magnitude of the non-proportional increase in oxygen uptake (V(O(2))) to power output relationship (V(O(2)) 'excess') at exercise intensities exceeding the lactate threshold (LT). Ten untrained, physically active men performed a bout of incremental cycling exercise until exhaustion before and after training. The mitochondrial DNA copy number, myosin heavy chain composition and content of uncoupling protein 3 and sarcoplasmic reticulum Ca(2+)-ATPases (SERCAs) were analysed in muscle biopsies taken from vastus lateralis before and after training. The training resulted in an enhancement of the power-generating capabilities at maximal oxygen uptake (V(O(2)max)) by ∼7% (P = 0.002) despite there being no changes in V(O(2)max) (P = 0.49). This effect was due to a considerable reduction in the magnitude of the V(O(2)) 'excess' (P 0.05) were found after training. We conclude that the training-induced increase in power-generating capabilities at V(O(2)max) was due to attenuation of the V(O(2)) 'excess' above the LT. This adaptive response seems to be related to the improvement of muscle metabolic stability, as judged by a lowering of plasma ammonia concentration. The enhancement of muscle metabolic stability after training could be caused by a decrease in ATP usage at a given power output owing to downregulation of SERCA2 pumps.

7. Relationship between linear and nonlinear dynamics of heart rate and impairment of lung function in COPD patients

Mazzuco A

2015-08-01

capacity/total lung capacity ratio, and residual volume/total lung capacity ratio. Significant and moderate associations were also observed between LF/HF ratio versus total gas volume (%, r=0.53; LF/HF ratio versus residual volume, %, r=0.52; and HF versus total gas volume (%, r=-0.53 (P<0.05. Linear regression analysis revealed that ΔRRi supine-M-RSA was independently related to DLCO (r=-0.77, r2=0.43, P<0.05. Conclusion: Responses of HRV indices were more prominent during M-RSA in moderate to severe COPD. Moreover, greater lung function impairment was related to poorer heart rate dynamics. Finally, impaired lung diffusion capacity was related to an altered parasympathetic response in these patients. Keywords: lung diffusion capacity, static lung volumes, rest hyperinflation, COPD, heart rate variability, cardiac autonomic nervous system

8. An update on modeling dose-response relationships: Accounting for correlated data structure and heterogeneous error variance in linear and nonlinear mixed models.

Gonçalves, M A D; Bello, N M; Dritz, S S; Tokach, M D; DeRouchey, J M; Woodworth, J C; Goodband, R D

2016-05-01

Advanced methods for dose-response assessments are used to estimate the minimum concentrations of a nutrient that maximizes a given outcome of interest, thereby determining nutritional requirements for optimal performance. Contrary to standard modeling assumptions, experimental data often present a design structure that includes correlations between observations (i.e., blocking, nesting, etc.) as well as heterogeneity of error variances; either can mislead inference if disregarded. Our objective is to demonstrate practical implementation of linear and nonlinear mixed models for dose-response relationships accounting for correlated data structure and heterogeneous error variances. To illustrate, we modeled data from a randomized complete block design study to evaluate the standardized ileal digestible (SID) Trp:Lys ratio dose-response on G:F of nursery pigs. A base linear mixed model was fitted to explore the functional form of G:F relative to Trp:Lys ratios and assess model assumptions. Next, we fitted 3 competing dose-response mixed models to G:F, namely a quadratic polynomial (QP) model, a broken-line linear (BLL) ascending model, and a broken-line quadratic (BLQ) ascending model, all of which included heteroskedastic specifications, as dictated by the base model. The GLIMMIX procedure of SAS (version 9.4) was used to fit the base and QP models and the NLMIXED procedure was used to fit the BLL and BLQ models. We further illustrated the use of a grid search of initial parameter values to facilitate convergence and parameter estimation in nonlinear mixed models. Fit between competing dose-response models was compared using a maximum likelihood-based Bayesian information criterion (BIC). The QP, BLL, and BLQ models fitted on G:F of nursery pigs yielded BIC values of 353.7, 343.4, and 345.2, respectively, thus indicating a better fit of the BLL model. The BLL breakpoint estimate of the SID Trp:Lys ratio was 16.5% (95% confidence interval [16.1, 17.0]). Problems with

9. Do relationships exist between the scope and intensity of quality improvement activities and hospital operation performance? A 10-year observation in Taiwan.

Chung, Kuo-Piao; Yu, Tsung-Hsien

2015-08-14

The relationship between the scope and intensity of quality improvement (QI) activities and hospital performance remains unclear. This study investigated the relationship between performance, external environment, and the scope and intensity of QI activities in hospitals. The study used a longitudinal observation. Data regarding the scope and intensity of QI activities were collected using a questionnaire survey among the administrative deputy superintendents / directors of quality management center in 139 hospitals. Hospital performance indicators were abstracted from the 2000-2009 national hospitals profiles. We adopted year 2000 as the baseline, and divided the study period into three 3-year periods. The Generalized Estimating Equations (GEE) model was used for the statistical analysis. Seventy-two hospitals responded to the survey, giving a response rate of 52%. The results showed a significant increase in the scope and intensity of QI activities between 2000 and 2009. The results also showed that the scope and intensity of a hospital's QI activities were associated with the scope and intensity of its competitors' QI activities in the previous period and its own prior performance. The scope of QI activities in the previous period was not significantly related to the selected hospital performance measures. However, the intensity of QI activities in the previous period showed a significant and positive relationship with the number of inpatients and the turnover of beds. The study demonstrates that the intensity of QI activities is associated with the external environment and the hospital's own performance in the previous period. Furthermore, some performance measures are associated with the intensity of the QI activities in the previous period.

10. A linear solvation energy relationship study for the reactivity of 2-substituted cyclohex-1-enecarboxylic and 2-substituted benzoic acids with diazodiphenylmethane in aprotic and protic solvents

JASMINA B. NIKOLIC

2007-12-01

Full Text Available The rate constants for the reaction of 2-substituted cyclohex-1-enylcarboxylic acids and the corresponding 2-substituted benzoic acids with diazodiphenyl methane were determined in various aprotic solvents at 30 ºC. In order to explain the kinetic results through solvent effects, the second order rate constants of the reaction of the examined acids were correlated using the Kamlet–Taft solvatechromic equation. The correlations of the kinetic data were carried out by means of multiple linear regression analysis and the solvent effects on the reaction rates were analyzed in terms of the contributions of the initial and transition state. The signs of the equation coefficients support the proposed reaction mechanism. The quantitative relationship between the molecular structure and the chemical reactivity is discussed, as well as the effect of geometry on the reactivity of the examined molecules.

11. Linear solvation energy relationships (LSER): 'rules of thumb' for Vi/100, π*, Βm, and αm estimation and use in aquatic toxicology

Hickey, James P.

1996-01-01

This chapter provides a listing of the increasing variety of organic moieties and heteroatom group for which Linear Solvation Energy Relationship (LSER) values are available, and the LSER variable estimation rules. The listings include values for typical nitrogen-, sulfur- and phosphorus-containing moieties, and general organosilicon and organotin groups. The contributions by an ion pair situation to the LSER values are also offered in Table 1, allowing estimation of parameters for salts and zwitterions. The guidelines permit quick estimation of values for the four primary LSER variables Vi/100, π*, Βm, and αm by summing the contribtuions from its components. The use of guidelines and Table 1 significantly simplifies computation of values for the LSER variables for most possible organic comppounds in the environment, including the larger compounds of environmental and biological interest.

12. Surveys of radon levels in homes in the United States: A test of the linear-no-threshold dose-response relationship for radiation carcinogenesis

Cohen, B.L.

1987-01-01

The University of Pittsburgh Radon Project for large scale measurements of radon concentrations in homes is described. Its principal research is to test the linear-no threshold dose-response relationship for radiation carcinogenesis by determining average radon levels in the 25 U.S. counties (within certain population ranges) with highest and lowest lung cancer rates. The theory predicts that the former should have about 3 times higher average radon levels than the latter, under the assumption that any correlation between exposure to radon and exposure to other causes of lung cancer is weak. The validity of this assumption is tested with data on average radon level vs replies to items on questionnaires; there is little correlation between radon levels in houses and smoking habits, educational attainment, or economic status of the occupants, or with urban vs rural environs which is an indicator of exposure to air pollution

13. Non-linear relationship between maternal work hours and child body weight: Evidence from the Western Australian Pregnancy Cohort (Raine) Study.

Li, Jianghong; Akaliyski, Plamen; Schäfer, Jakob; Kendall, Garth; Oddy, Wendy H; Stanley, Fiona; Strazdins, Lyndall

2017-08-01

Using longitudinal data from the Western Australia Pregnancy Cohort (Raine) Study and both random-effects and fixed-effects models, this study examined the connection between maternal work hours and child overweight or obesity. Following children in two-parent families from early childhood to early adolescence, multivariate analyses revealed a non-linear and developmentally dynamic relationship. Among preschool children (ages 2 to 5), we found lower likelihood of child overweight and obesity when mothers worked 24 h or less per week, compared to when mothers worked 35 or more hours. This effect was stronger in low-to-medium income families. For older children (ages 8 to 14), compared to working 35-40 h a week, working shorter hours (1-24, 25-34) or longer hours (41 or more) was both associated with increases in child overweight and obesity. These non-linear effects were more pronounced in low-to-medium income families, particularly when fathers also worked long hours. Copyright © 2017 Elsevier Ltd. All rights reserved.

14. A note on the relationships between multiple imputation, maximum likelihood and fully Bayesian methods for missing responses in linear regression models.

Chen, Qingxia; Ibrahim, Joseph G

2014-07-01

Multiple Imputation, Maximum Likelihood and Fully Bayesian methods are the three most commonly used model-based approaches in missing data problems. Although it is easy to show that when the responses are missing at random (MAR), the complete case analysis is unbiased and efficient, the aforementioned methods are still commonly used in practice for this setting. To examine the performance of and relationships between these three methods in this setting, we derive and investigate small sample and asymptotic expressions of the estimates and standard errors, and fully examine how these estimates are related for the three approaches in the linear regression model when the responses are MAR. We show that when the responses are MAR in the linear model, the estimates of the regression coefficients using these three methods are asymptotically equivalent to the complete case estimates under general conditions. One simulation and a real data set from a liver cancer clinical trial are given to compare the properties of these methods when the responses are MAR.

15. Non-Linearity of dose-effect relationship on the example of cytogenetic effects in plant cells at low level exposure to ionising radiation

Oudalova, Alla; Geras'kin, Stanislav; Dikarev, Vladimir; Dikareva, Nina; Chernonog, Elena; Copplestone, David; Evseeva, Tatyana

2006-01-01

Over several decades, modelling the effects of ionizing radiation on biological system has relied on the target principle [Timofeeff-Ressovsky et al., 1935], which assumes that cell damage or modification to genes appear as a direct consequence of the exposure of biological macromolecules to charged particles. Furthermore, it is assumed that there is no threshold for the induction of biological damage and that the effects observed are proportional to the energy absorbed. Following this principle, the average number of hits per target should increase linearly with dose, and the yield of mutations per unit of dose is assumed to be the same at both low and high doses (linearity of response). This principle has served as the scientific background for the linear no-threshold (LNT) concept that forms the basis for the radiological protection for the public and the environment [ICRP, 1990]. It follows from the LNT that there is an additional risk for human health from exposure to any radiation level, even below natural background. Since the mid 50's, however, the scientific basis for the LNT concept has been challenged as experimental data have shown that, at low doses, there was a non linear relationship in the dose response. Luchnik and Timofeeff-Ressovsky were the first who showed a non-linear response to a low dose exposure [Luchnik, 1957; Timofeeff-Ressovsky and Luchnik, 1960]. Since then, many data have been accumulated which contradict the LNT model at low doses and dose rates. However, the hit-effect paradigm has become such a strong and indissoluble fact that it has persisted even under the growing pressure of scientific evidence for phenomena at low dose exposure that can not be successfully accounted for by the LNT concept. In recent years, additional information on non-targeted effects of radiation has been accumulated following the first reports of an adaptive response in human lymphocytes [Olivieri et al., 1984] as well as bystander mutagenic effect of alpha

16. Non-Linearity of dose-effect relationship on the example of cytogenetic effects in plant cells at low level exposure to ionising radiation

Oudalova, Alla; Geras' kin, Stanislav; Dikarev, Vladimir; Dikareva, Nina; Chernonog, Elena [Russian Institute of Agricultural Radiology and Agroecology, RIARAE, 249032 Obninsk (Russian Federation); Copplestone, David [Environment Agency, Millbank Tower, 25th. Floor, 21/24 Millbank, London, SW1P 4XL (United Kingdom); Evseeva, Tatyana [Institute of Biology, Kommunisticheskaya st., 28 Syktyvkar 167610, Komi Republic (Russian Federation)

2006-07-01

Over several decades, modelling the effects of ionizing radiation on biological system has relied on the target principle [Timofeeff-Ressovsky et al., 1935], which assumes that cell damage or modification to genes appear as a direct consequence of the exposure of biological macromolecules to charged particles. Furthermore, it is assumed that there is no threshold for the induction of biological damage and that the effects observed are proportional to the energy absorbed. Following this principle, the average number of hits per target should increase linearly with dose, and the yield of mutations per unit of dose is assumed to be the same at both low and high doses (linearity of response). This principle has served as the scientific background for the linear no-threshold (LNT) concept that forms the basis for the radiological protection for the public and the environment [ICRP, 1990]. It follows from the LNT that there is an additional risk for human health from exposure to any radiation level, even below natural background. Since the mid 50's, however, the scientific basis for the LNT concept has been challenged as experimental data have shown that, at low doses, there was a non linear relationship in the dose response. Luchnik and Timofeeff-Ressovsky were the first who showed a non-linear response to a low dose exposure [Luchnik, 1957; Timofeeff-Ressovsky and Luchnik, 1960]. Since then, many data have been accumulated which contradict the LNT model at low doses and dose rates. However, the hit-effect paradigm has become such a strong and indissoluble fact that it has persisted even under the growing pressure of scientific evidence for phenomena at low dose exposure that can not be successfully accounted for by the LNT concept. In recent years, additional information on non-targeted effects of radiation has been accumulated following the first reports of an adaptive response in human lymphocytes [Olivieri et al., 1984] as well as bystander mutagenic effect of

17. Co-existence of Paragonimus harinasutai and Paragonimus bangkokensis metacercariae in fresh water crab hosts in central Viet Nam with special emphasis on their close phylogenetic relationship.

Doanh, Pham Ngoc; Hien, Hoang Van; Nonaka, Nariaki; Horii, Yoichiro; Nawa, Yukifumi

2012-09-01

During our epidemiological surveys for Paragonimus species in central Viet Nam, we found four morphologically different Paragonimus metacercariae in mountainous crabs. They were identified as metacercariae of Paragonimus westermani, P. bangkokensis, P. proliferus, and P. harinasutai in the order of their prevalence in crab hosts. This is the first discovery of P. harinasutai in Viet Nam, co-inhabiting with P. bangkokensis and other species. Metacercariae of P. harinasutai were given orally to a cat to obtain adult worms. Then, ITS2 and CO1 sequences of metacercariae and adults of P. harinasutai, and metacercariae of P. bangkokensis collected from the same place were determined for analyses of phylogenetic relationships to other P. harinasutai and P. bangkokensis populations as well as related species. The results of molecular analyses showed that P. harinasutai from Quang Binh province of central Viet Nam was almost completely identical with those from Vientiane, Lao PDR; P. bangkokensis from Quang Binh, Viet Nam was also almost completely identical with those from Lao PDR and from Quang Ninh province, Viet Nam. Except for one P. harinasutai isolate from China, all populations of P. harinasutai and P. bangkokensis from Thailand, Lao and Viet Nam make a single clade in both ITS2 and CO1 trees. In ITS2 sequences, AT deletion and ATC insertion were observed in some isolates of both species, indicating recent gene flow between P. harinasutai and P. bangkokensis. Moreover, because of their extremely high genetic similarities and their co-inhabitation in the same crab hosts found in Thailand, Lao PDR and Viet Nam, they should be considered as the sister species at the early stage of divergence. In addition, P. microrchis previously described from Yunnan, China should be placed as the synonym of P. harinasutai, because of their morphological and molecular similarities. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

18. MODELLING THE RELATIONSHIP BETWEEN LAND SURFACE TEMPERATURE AND LANDSCAPE PATTERNS OF LAND USE LAND COVER CLASSIFICATION USING MULTI LINEAR REGRESSION MODELS

A. M. Bernales

2016-06-01

Full Text Available The threat of the ailments related to urbanization like heat stress is very prevalent. There are a lot of things that can be done to lessen the effect of urbanization to the surface temperature of the area like using green roofs or planting trees in the area. So land use really matters in both increasing and decreasing surface temperature. It is known that there is a relationship between land use land cover (LULC and land surface temperature (LST. Quantifying this relationship in terms of a mathematical model is very important so as to provide a way to predict LST based on the LULC alone. This study aims to examine the relationship between LST and LULC as well as to create a model that can predict LST using class-level spatial metrics from LULC. LST was derived from a Landsat 8 image and LULC classification was derived from LiDAR and Orthophoto datasets. Class-level spatial metrics were created in FRAGSTATS with the LULC and LST as inputs and these metrics were analysed using a statistical framework. Multi linear regression was done to create models that would predict LST for each class and it was found that the spatial metric “Effective mesh size” was a top predictor for LST in 6 out of 7 classes. The model created can still be refined by adding a temporal aspect by analysing the LST of another farming period (for rural areas and looking for common predictors between LSTs of these two different farming periods.

19. Chlamydia pneumoniae and stroke: is there a direct relationship? Chlamydia pneumoniae e acidente vascular cerebral aterotrombótico: existe relação direta?

Rubens J. Gagliardi

2009-09-01

Full Text Available OBJECTIVE: To investigate the possible relationship between atherothrombotic stroke and Chlamydia pneumoniae. METHOD: 150 patients with carotid atherothrombosis were enrolled. The casuistic was divided in three groups: ischemic stroke (IS: 65 patients; transient ischemic attack (TIA: 26 patients; and control: 59. The IS or TIA onset was up to 30 days from the beginning of the study. Carotid atheromatoses was diagnosed by Doppler-ultrasonography. Patients with cardioembolic risk or non-atherothrombotic origin were excluded. Comparisons were done between the three groups, and within each group according to the different age sub-groups, to the main arteries affected, and to the atherogenic risk factors. Bacteria detection was done using polimerase chain reaction. RESULTS: Only one patient tested positive for C. pneumoniae belonging to the control group. CONCLUSION: These results do not suggest that C. pneumoniae participated in the onset of IS or TIA or that it has a role in carotid plaque destabilization.OBJETIVO: Investigar a possível relação entre Chlamydia pneumoniae e acidente vascular cerebral aterotrombótico (AVC. MÉTODO: 150 pacientes com aterotrombose carotídea foram estudados. A casuística foi dividida em 3 grupos: AVC: 65 pacientes; ataque isquêmico transitório (AIT: 26 pacientes e controles: 59. O início do AVC ou AIT era até 30 dias da inclusão no estudo. A ateromatose carotídea foi diagnosticada por ultrassonografia com Doppler. Os pacientes com risco cárdio-embólico ou sem evidência de aterotrombose foram excluídos. Foram estabelecidas comparações entre os 3 grupos e dentro de cada grupo, formado sub-grupos de acordo com diferentes idades, território arterial comprometido e fatores de risco. A detecção da bactéria foi feita por reação de polimerização em cadeia. RESULTADOS: Somente um paciente, pertencente ao grupo controle, teve resultado positivo. CONCLUSÃO: Estes achados não sugerem que a C. pneumoniae

20. Non-linear Relationship between BOLD Activation and Amplitude of Beta Oscillations in the Supplementary Motor Area during Rhythmic Finger Tapping and Internal Timing

Gompf, Florian; Pflug, Anja; Laufs, Helmut; Kell, Christian A.

2017-01-01

Functional imaging studies using BOLD contrasts have consistently reported activation of the supplementary motor area (SMA) both during motor and internal timing tasks. Opposing findings, however, have been shown for the modulation of beta oscillations in the SMA. While movement suppresses beta oscillations in the SMA, motor and non-motor tasks that rely on internal timing increase the amplitude of beta oscillations in the SMA. These independent observations suggest that the relationship between beta oscillations and BOLD activation is more complex than previously thought. Here we set out to investigate this rapport by examining beta oscillations in the SMA during movement with varying degrees of internal timing demands. In a simultaneous EEG-fMRI experiment, 20 healthy right-handed subjects performed an auditory-paced finger-tapping task. Internal timing was operationalized by including conditions with taps on every fourth auditory beat, which necessitates generation of a slow internal rhythm, while tapping to every auditory beat reflected simple auditory-motor synchronization. In the SMA, BOLD activity increased and power in both the low and the high beta band decreased expectedly during each condition compared to baseline. Internal timing was associated with a reduced desynchronization of low beta oscillations compared to conditions without internal timing demands. In parallel with this relative beta power increase, internal timing activated the SMA more strongly in terms of BOLD. This documents a task-dependent non-linear relationship between BOLD and beta-oscillations in the SMA. We discuss different roles of beta synchronization and desynchronization in active processing within the same cortical region. PMID:29249950

1. Non-linear Relationship between BOLD Activation and Amplitude of Beta Oscillations in the Supplementary Motor Area during Rhythmic Finger Tapping and Internal Timing.

Gompf, Florian; Pflug, Anja; Laufs, Helmut; Kell, Christian A

2017-01-01

Functional imaging studies using BOLD contrasts have consistently reported activation of the supplementary motor area (SMA) both during motor and internal timing tasks. Opposing findings, however, have been shown for the modulation of beta oscillations in the SMA. While movement suppresses beta oscillations in the SMA, motor and non-motor tasks that rely on internal timing increase the amplitude of beta oscillations in the SMA. These independent observations suggest that the relationship between beta oscillations and BOLD activation is more complex than previously thought. Here we set out to investigate this rapport by examining beta oscillations in the SMA during movement with varying degrees of internal timing demands. In a simultaneous EEG-fMRI experiment, 20 healthy right-handed subjects performed an auditory-paced finger-tapping task. Internal timing was operationalized by including conditions with taps on every fourth auditory beat, which necessitates generation of a slow internal rhythm, while tapping to every auditory beat reflected simple auditory-motor synchronization. In the SMA, BOLD activity increased and power in both the low and the high beta band decreased expectedly during each condition compared to baseline. Internal timing was associated with a reduced desynchronization of low beta oscillations compared to conditions without internal timing demands. In parallel with this relative beta power increase, internal timing activated the SMA more strongly in terms of BOLD. This documents a task-dependent non-linear relationship between BOLD and beta-oscillations in the SMA. We discuss different roles of beta synchronization and desynchronization in active processing within the same cortical region.

2. Characterizing the relationship between temperature and mortality in tropical and subtropical cities: a distributed lag non-linear model analysis in Hue, Viet Nam, 2009-2013.

Dang, Tran Ngoc; Seposo, Xerxes T; Duc, Nguyen Huu Chau; Thang, Tran Binh; An, Do Dang; Hang, Lai Thi Minh; Long, Tran Thanh; Loan, Bui Thi Hong; Honda, Yasushi

2016-01-01

The relationship between temperature and mortality has been found to be U-, V-, or J-shaped in developed temperate countries; however, in developing tropical/subtropical cities, it remains unclear. Our goal was to investigate the relationship between temperature and mortality in Hue, a subtropical city in Viet Nam. We collected daily mortality data from the Vietnamese A6 mortality reporting system for 6,214 deceased persons between 2009 and 2013. A distributed lag non-linear model was used to examine the temperature effects on all-cause and cause-specific mortality by assuming negative binomial distribution for count data. We developed an objective-oriented model selection with four steps following the Akaike information criterion (AIC) rule (i.e. a smaller AIC value indicates a better model). High temperature-related mortality was more strongly associated with short lags, whereas low temperature-related mortality was more strongly associated with long lags. The low temperatures increased risk in all-category mortality compared to high temperatures. We observed elevated temperature-mortality risk in vulnerable groups: elderly people (high temperature effect, relative risk [RR]=1.42, 95% confidence interval [CI]=1.11-1.83; low temperature effect, RR=2.0, 95% CI=1.13-3.52), females (low temperature effect, RR=2.19, 95% CI=1.14-4.21), people with respiratory disease (high temperature effect, RR=2.45, 95% CI=0.91-6.63), and those with cardiovascular disease (high temperature effect, RR=1.6, 95% CI=1.15-2.22; low temperature effect, RR=1.99, 95% CI=0.92-4.28). In Hue, the temperature significantly increased the risk of mortality, especially in vulnerable groups (i.e. elderly, female, people with respiratory and cardiovascular diseases). These findings may provide a foundation for developing adequate policies to address the effects of temperature on health in Hue City.

3. Linear algebra

Shilov, Georgi E

1977-01-01

Covers determinants, linear spaces, systems of linear equations, linear functions of a vector argument, coordinate transformations, the canonical form of the matrix of a linear operator, bilinear and quadratic forms, Euclidean spaces, unitary spaces, quadratic forms in Euclidean and unitary spaces, finite-dimensional space. Problems with hints and answers.

4. Characterization of volatile organic compound adsorption on multiwall carbon nanotubes under different levels of relative humidity using linear solvation energy relationship

Li, Mei-syue; Wu, Siang Chen; Shih, Yang-hsin

2016-01-01

Highlights: • LSER equations successfully predicted VOC sorption on MCNT at different humidity. • The five parameters in LSER could be narrowed down to three ones. • Main interaction is dispersion and partly dipolarity as well as hydrogen-bonds. • With increasing RH, it changes to cavity formation and hydrogen-bond basicity. • This approach can facilitate the VOC control design and the fate prediction. - Abstract: Multiwall carbon nanotubes (MWCNTs) have been used as an adsorbent for evaluating the gas/solid partitioning of selected volatile organic compounds (VOCs). In this study, 15 VOCs were probed to determine their gas/solid partitioning coefficient (Log K d ) using inverse gas chromatography at different relative humidity (RH) levels. Interactions between MWCNTs and VOCs were analyzed by regressing the observed Log K d with the linear solvation energy relationship (LSER). The results demonstrate that the MWCNT carbonyl and carboxyl groups provide high adsorption capacity for the VOCs (Log K d 3.72–5.24 g/kg/g/L) because of the π-/n-electron pair interactions and hydrogen-bond acidity. The increasing RH gradually decreased the Log K d and shifted the interactions to dipolarity/polarizability, hydrogen-bond basicity, and cavity formation. The derived LSER equations provided adequate fits of Log K d , which is useful for VOC-removal processes and fate prediction of VOC contaminants by MWCNT adsorption in the environment.

5. Quantitative structure-property relationship study of n-octanol-water partition coefficients of some of diverse drugs using multiple linear regression

Ghasemi, Jahanbakhsh; Saaidpour, Saadi

2007-01-01

A quantitative structure-property relationship (QSPR) study was performed to develop models those relate the structures of 150 drug organic compounds to their n-octanol-water partition coefficients (log P o/w ). Molecular descriptors derived solely from 3D structures of the molecular drugs. A genetic algorithm was also applied as a variable selection tool in QSPR analysis. The models were constructed using 110 molecules as training set, and predictive ability tested using 40 compounds. Modeling of log P o/w of these compounds as a function of the theoretically derived descriptors was established by multiple linear regression (MLR). Four descriptors for these compounds molecular volume (MV) (geometrical), hydrophilic-lipophilic balance (HLB) (constitutional), hydrogen bond forming ability (HB) (electronic) and polar surface area (PSA) (electrostatic) are taken as inputs for the model. The use of descriptors calculated only from molecular structure eliminates the need for experimental determination of properties for use in the correlation and allows for the estimation of log P o/w for molecules not yet synthesized. Application of the developed model to a testing set of 40 drug organic compounds demonstrates that the model is reliable with good predictive accuracy and simple formulation. The prediction results are in good agreement with the experimental value. The root mean square error of prediction (RMSEP) and square correlation coefficient (R 2 ) for MLR model were 0.22 and 0.99 for the prediction set log P o/w

6. Characterization of volatile organic compound adsorption on multiwall carbon nanotubes under different levels of relative humidity using linear solvation energy relationship

Li, Mei-syue; Wu, Siang Chen; Shih, Yang-hsin, E-mail: yhs@ntu.edu.tw

2016-09-05

Highlights: • LSER equations successfully predicted VOC sorption on MCNT at different humidity. • The five parameters in LSER could be narrowed down to three ones. • Main interaction is dispersion and partly dipolarity as well as hydrogen-bonds. • With increasing RH, it changes to cavity formation and hydrogen-bond basicity. • This approach can facilitate the VOC control design and the fate prediction. - Abstract: Multiwall carbon nanotubes (MWCNTs) have been used as an adsorbent for evaluating the gas/solid partitioning of selected volatile organic compounds (VOCs). In this study, 15 VOCs were probed to determine their gas/solid partitioning coefficient (Log K{sub d}) using inverse gas chromatography at different relative humidity (RH) levels. Interactions between MWCNTs and VOCs were analyzed by regressing the observed Log K{sub d} with the linear solvation energy relationship (LSER). The results demonstrate that the MWCNT carbonyl and carboxyl groups provide high adsorption capacity for the VOCs (Log K{sub d} 3.72–5.24 g/kg/g/L) because of the π-/n-electron pair interactions and hydrogen-bond acidity. The increasing RH gradually decreased the Log K{sub d} and shifted the interactions to dipolarity/polarizability, hydrogen-bond basicity, and cavity formation. The derived LSER equations provided adequate fits of Log K{sub d}, which is useful for VOC-removal processes and fate prediction of VOC contaminants by MWCNT adsorption in the environment.

7. Relationship between metallothioneins and metals in a natural population of the clam Ruditapes decussatus from Sfax coast: a non-linear model using Box-Cox transformation.

Hamza-Chaffai, A; Amiard, J C; Cosson, R P

1999-06-01

Cadmium, copper and zinc were determined concomitantly with metallothionein-like proteins (MTLPs) in the subcellular fractions of Ruditapes decussatus digestive gland. This study covered 4 months and aimed to evaluate the effect of metal pollution and other factors such as sex, size and reproductive state on MTLP levels. Copper concentrations did not vary with month, however Cd and Zn concentrations showed high levels during August. Organisms showing low cadmium concentrations presented the highest cadmium percentages in the soluble fraction (SF) containing MTLPs. However for high cadmium concentrations, the insoluble fraction (IF) was implicated in cadmium association. MTLP levels varied according to the month, the sex and the size of the organisms. A non-linear model based on the Box-Cox transformation, was proposed to describe a positive and a significant relationship between MTLPs and the studied metals. A model including sex and size showed that these two factors affected MTLP levels, but were less important than metals. Males of R. decussatus showed higher significant correlations between MTLP levels and cadmium than females. Moreover, the effect of size and reproductive state on MTLP levels was less perceptible in males than in females. As a result, MTLPs in males of R. decussatus could be proposed as suitable biomarker for detecting metal contamination.

8. About the existing linear relation between the material velocity and the shock wave velocity propagating inside a metal; Au sujet de la relation lineaire existant entre la vitesse materielle et la vitesse de l'onde de choc se propageant dans un metal

Berger, Jean; Joigneau, Suzanne [Commissariat a l' energie atomique et aux energies alternatives - CEA (France)

1960-07-01

It was found that, for solids and more particularly for metals, in huge fields of shock pressure, the wave velocity is a linear function of the material velocity. A theoretical calculation allows to demonstrate this linear law and to calculate its parameters which are compared to experimental data. Reprint of a paper published in Comptes rendus des seances de l'Academie des Sciences, t. 249, p. 2506-2508, sitting of 9 December 1959 [French] Il a ete constate que, pour les solides et plus particulierement pour les metaux, dans de larges domaines de pression de choc, la vitesse de l'onde etait une fonction lineaire de la vitesse materielle. Un calcul theorique nous permet de retrouver cette loi lineaire et d'en calculer les parametres; ceux-ci sont alors compares aux donnees experimentales. Reproduction d'un article publie dans les Comptes rendus des seances de l'Academie des Sciences, t. 249, p. 2506-2508, seance du 9 decembre 1959.

9. Study of the frequency modulation of various U.H.F. signals occurring in a linear electron accelerator; Etude de la modulation de frequence de divers signaux U.H.F. existant dans un accelerateur lineaire d'electrons

Bergere, R; Veyssiere, A; Daujat, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1966-06-01

This paper contains a digest of a series of studies on the frequency modulation of U.H.F. fields and signals associated with the linear electron accelerator at Saclay. We first consider the frequency modulation of a U. H. F. pulse before its injection into an accelerating structure and after its subsequent propagation when no accelerated electrons are present. We then apply a similar analysis to the frequency modulation due to the direct interaction of the electron beam itself, and the accelerating U.H.F. fields. Finally we consider the phase modulation of the elementary electron packet itself. This phase modulation can be correctly interpreted by considering the dynamics of the electron beam as such. This analysis moreover, gives a correct interpretation of the evolution of the phase modulation with time, as the elementary electron packets move along with the sinusoidal U.H.F. accelerating fields. (authors) [French] Cet article resume les etudes faites sur l'accelerateur lineaire d'electrons de Saclay a propos de la modulation de frequence des divers signaux U.H.F. presents autour de l'accelerateur. On etudie d'abord la modulation de frequence des impulsions U.H.F. entrant sur la structure acceleratrice ou transmises par cette structure en l'absence de faisceau d'electrons acceleres. On analyse ensuite la modulation de frequence resultant de l'interaction d'une de ces ondes avec le faisceau d'electrons acceleres. On etudie enfin, la modulation de phase des divers paquets elementaires constituant une impulsion d'electrons acceleres. On montre comment cette modulation de phase peut s'expliquer par des considerations sur la dynamique du faisceau et conduire a une representation dans les divers cas possibles de l'evolution de la phase d'accrochage des electrons sur l'onde sinusoidale progressive de champ accelerateur. (auteurs)

10. Finite-dimensional linear algebra

Gockenbach, Mark S

2010-01-01

Some Problems Posed on Vector SpacesLinear equationsBest approximationDiagonalizationSummaryFields and Vector SpacesFields Vector spaces Subspaces Linear combinations and spanning sets Linear independence Basis and dimension Properties of bases Polynomial interpolation and the Lagrange basis Continuous piecewise polynomial functionsLinear OperatorsLinear operatorsMore properties of linear operatorsIsomorphic vector spaces Linear operator equations Existence and uniqueness of solutions The fundamental theorem; inverse operatorsGaussian elimination Newton's method Linear ordinary differential eq

11. Linear models with R

Faraway, Julian J

2014-01-01

A Hands-On Way to Learning Data AnalysisPart of the core of statistics, linear models are used to make predictions and explain the relationship between the response and the predictors. Understanding linear models is crucial to a broader competence in the practice of statistics. Linear Models with R, Second Edition explains how to use linear models in physical science, engineering, social science, and business applications. The book incorporates several improvements that reflect how the world of R has greatly expanded since the publication of the first edition.New to the Second EditionReorganiz

12. Investigation of Relationship Between Hydrologic Processes of Precipitation, Evaporation and Stream Flow Using Linear Time Series Models (Case study: Western Basins of Lake Urmia

M. Moravej

2016-02-01

Full Text Available Introduction: Studying the hydrological cycle, especially in large scales such as water catchments, is difficult and complicated despite the fact that the numbers of hydrological components are limited. This complexity rises from complex interactions between hydrological components and environment. Recognition, determination and modeling of all interactive processes are needed to address this issue, but it's not feasible for dealing with practical engineering problems. So, it is more convenient to consider hydrological components as stochastic phenomenon, and use stochastic models for modeling them. Stochastic simulation of time series models related to water resources, particularly hydrologic time series, have been widely used in recent decades in order to solve issues pertaining planning and management of water resource systems. In this study time series models fitted to the precipitation, evaporation and stream flow series separately and the relationships between stream flow and precipitation processes are investigated. In fact, the three mentioned processes should be modeled in parallel to each other in order to acquire a comprehensive vision of hydrological conditions in the region. Moreover, the relationship between the hydrologic processes has been mostly studied with respect to their trends. It is desirable to investigate the relationship between trends of hydrological processes and climate change, while the relationship of the models has not been taken into consideration. The main objective of this study is to investigate the relationship between hydrological processes and their effects on each other and the selected models. Material and Method: In the current study, the four sub-basins of Lake Urmia Basin namely Zolachay (A, Nazloochay (B, Shahrchay (C and Barandoozchay (D were considered. Precipitation, evaporation and stream flow time series were modeled by linear time series. Fundamental assumptions of time series analysis namely

13. Characterizing the relationship between temperature and mortality in tropical and subtropical cities: a distributed lag non-linear model analysis in Hue, Viet Nam, 2009–2013

Dang, Tran Ngoc; Seposo, Xerxes T.; Duc, Nguyen Huu Chau; Thang, Tran Binh; An, Do Dang; Hang, Lai Thi Minh; Long, Tran Thanh; Loan, Bui Thi Hong; Honda, Yasushi

2016-01-01

Background The relationship between temperature and mortality has been found to be U-, V-, or J-shaped in developed temperate countries; however, in developing tropical/subtropical cities, it remains unclear. Objectives Our goal was to investigate the relationship between temperature and mortality in Hue, a subtropical city in Viet Nam. Design We collected daily mortality data from the Vietnamese A6 mortality reporting system for 6,214 deceased persons between 2009 and 2013. A distributed lag non-linear model was used to examine the temperature effects on all-cause and cause-specific mortality by assuming negative binomial distribution for count data. We developed an objective-oriented model selection with four steps following the Akaike information criterion (AIC) rule (i.e. a smaller AIC value indicates a better model). Results High temperature-related mortality was more strongly associated with short lags, whereas low temperature-related mortality was more strongly associated with long lags. The low temperatures increased risk in all-category mortality compared to high temperatures. We observed elevated temperature-mortality risk in vulnerable groups: elderly people (high temperature effect, relative risk [RR]=1.42, 95% confidence interval [CI]=1.11–1.83; low temperature effect, RR=2.0, 95% CI=1.13–3.52), females (low temperature effect, RR=2.19, 95% CI=1.14–4.21), people with respiratory disease (high temperature effect, RR=2.45, 95% CI=0.91–6.63), and those with cardiovascular disease (high temperature effect, RR=1.6, 95% CI=1.15–2.22; low temperature effect, RR=1.99, 95% CI=0.92–4.28). Conclusions In Hue, the temperature significantly increased the risk of mortality, especially in vulnerable groups (i.e. elderly, female, people with respiratory and cardiovascular diseases). These findings may provide a foundation for developing adequate policies to address the effects of temperature on health in Hue City. PMID:26781954

14. Characterizing the relationship between temperature and mortality in tropical and subtropical cities: a distributed lag non-linear model analysis in Hue, Viet Nam, 2009–2013

Tran Ngoc Dang

2016-01-01

Full Text Available Background: The relationship between temperature and mortality has been found to be U-, V-, or J-shaped in developed temperate countries; however, in developing tropical/subtropical cities, it remains unclear. Objectives: Our goal was to investigate the relationship between temperature and mortality in Hue, a subtropical city in Viet Nam. Design: We collected daily mortality data from the Vietnamese A6 mortality reporting system for 6,214 deceased persons between 2009 and 2013. A distributed lag non-linear model was used to examine the temperature effects on all-cause and cause-specific mortality by assuming negative binomial distribution for count data. We developed an objective-oriented model selection with four steps following the Akaike information criterion (AIC rule (i.e. a smaller AIC value indicates a better model. Results: High temperature-related mortality was more strongly associated with short lags, whereas low temperature-related mortality was more strongly associated with long lags. The low temperatures increased risk in all-category mortality compared to high temperatures. We observed elevated temperature-mortality risk in vulnerable groups: elderly people (high temperature effect, relative risk [RR]=1.42, 95% confidence interval [CI]=1.11–1.83; low temperature effect, RR=2.0, 95% CI=1.13–3.52, females (low temperature effect, RR=2.19, 95% CI=1.14–4.21, people with respiratory disease (high temperature effect, RR=2.45, 95% CI=0.91–6.63, and those with cardiovascular disease (high temperature effect, RR=1.6, 95% CI=1.15–2.22; low temperature effect, RR=1.99, 95% CI=0.92–4.28. Conclusions: In Hue, the temperature significantly increased the risk of mortality, especially in vulnerable groups (i.e. elderly, female, people with respiratory and cardiovascular diseases. These findings may provide a foundation for developing adequate policies to address the effects of temperature on health in Hue City.

15. Entrepreneurship Education: Non-Linearity in the Satisfaction – Continuation Relationship = Podjetniško izobraževanje: nelineranost v razmerju med zadovoljstvom in nadaljevanjem izobraževanja

Boštjan Antoncic

2007-06-01

Full Text Available In this paper we propose one possible explanation of the interrelationships between education continuation or avoidance, satisfaction level, and experience (entrepreneurial maturity of potential and practicing entrepreneurs. By using the cusp catastrophe model we propose that relationship between education satisfaction and continuation tends to be linear for less experienced entrepreneurs (pre-entrepreneurs, whereas for more experienced entrepreneurs the relationship is proposed to be positive but non-linear (s-shaped. Data were collected with a structured questionnaire from 122 participants in management and entrepreneurship education and training programs. The proposed model was tested with linear and non-linear regression equations. The relationship between satisfaction and continuation (loyalty was found to be positive for all entrepreneurial and nonentrepreneurial groups. The appropriate functional form for the satisfaction-continuation relationship discovered for non-entrepreneurs and people that are only thinking about entrepreneurship (maybe-entrepreneurs is close to linear and less steep than for more entrepreneurial groups. By contrast, prospective entrepreneurs (people in the process of pre-start up and practicing entrepreneurs tend to be more sensitive to their education satisfaction in their future education continuation decisions. The appropriate functional form for these entrepreneurial groups tends to be cubical, which is close to the s-shaped function proposed in the cusp model. The study provided evidence that the relationships between entrepreneurial maturity, education satisfaction and education continuation may be modeled as a cusp catastrophe model. The proposed model can be helpful for education and for training providers (and marketers in explaining and predicting of education loyalty or the switching behavior of entrepreneurs.

16. Effects of oxygen on intrinsic radiation sensitivity: A test of the relationship between aerobic and hypoxic linear-quadratic (LQ) model parameters

Carlson, David J.; Stewart, Robert D.; Semenenko, Vladimir A.

2006-01-01

The poor treatment prognosis for tumors with high levels of hypoxia is usually attributed to the decreased sensitivity of hypoxic cells to ionizing radiation. Mechanistic considerations suggest that linear quadratic (LQ) survival model radiosensitivity parameters for hypoxic (H) and aerobic (A) cells are related by α H =α A /oxygen enhancement ratio (OER) and (α/β) H =OER(α/β) A . The OER parameter may be interpreted as the ratio of the dose to the hypoxic cells to the dose to the aerobic cells required to produce the same number of DSBs per cell. The validity of these expressions is tested against survival data for mammalian cells irradiated in vitro with low- and high-LET radiation. Estimates of hypoxic and aerobic radiosensitivity parameters are derived from independent and simultaneous least-squares fits to the survival data. An external bootstrap procedure is used to test whether independent fits to the survival data give significantly better predictions than simultaneous fits to the aerobic and hypoxic data. For low-LET radiation, estimates of the OER derived from the in vitro data are between 2.3 and 3.3 for extreme levels of hypoxia. The estimated range for the OER is similar to the oxygen enhancement ratios reported in the literature for the initial yield of DSBs. The half-time for sublethal damage repair was found to be independent of oxygen concentration. Analysis of patient survival data for cervix cancer suggests an average OER less than or equal to 1.5, which corresponds to a pO 2 of 5 mm Hg (0.66%) in the in vitro experiments. Because the OER derived from the cervix cancer data is averaged over cells at all oxygen levels, cells irradiated in vivo under extreme levels of hypoxia (<0.5 mm Hg) may have an OER substantially higher than 1.5. The reported analyses of in vitro data, as well as mechanistic considerations, provide strong support for the expressions relating hypoxic and aerobic radiosensitivity parameters. The formulas are also useful

17. Linear gate

Suwono.

1978-01-01

A linear gate providing a variable gate duration from 0,40μsec to 4μsec was developed. The electronic circuity consists of a linear circuit and an enable circuit. The input signal can be either unipolar or bipolar. If the input signal is bipolar, the negative portion will be filtered. The operation of the linear gate is controlled by the application of a positive enable pulse. (author)

18. Linear Accelerators

Vretenar, M

2014-01-01

The main features of radio-frequency linear accelerators are introduced, reviewing the different types of accelerating structures and presenting the main characteristics aspects of linac beam dynamics

19. Linearity enigmas in ecology

Patten, B.C.

1983-04-01

Two issues concerning linearity or nonlinearity of natural systems are considered. Each is related to one of the two alternative defining properties of linear systems, superposition and decomposition. Superposition exists when a linear combination of inputs to a system results in the same linear combination of outputs that individually correspond to the original inputs. To demonstrate this property it is necessary that all initial states and inputs of the system which impinge on the output in question be included in the linear combination manipulation. As this is difficult or impossible to do with real systems of any complexity, nature appears nonlinear even though it may be linear. A linear system that displays nonlinear behavior for this reason is termed pseudononlinear. The decomposition property exists when the dynamic response of a system can be partitioned into an input-free portion due to state plus a state-free portion due to input. This is a characteristic of all linear systems, but not of nonlinear systems. Without the decomposition property, it is not possible to distinguish which portions of a system's behavior are due to innate characteristics (self) vs. outside conditions (environment), which is an important class of questions in biology and ecology. Some philosophical aspects of these findings are then considered. It is suggested that those ecologists who hold to the view that organisms and their environments are separate entities are in effect embracing a linear view of nature, even though their belief systems and mathematical models tend to be nonlinear. On the other hand, those who consider that organism-environment complex forms a single inseparable unit are implictly involved in non-linear thought, which may be in conflict with the linear modes and models that some of them use. The need to rectify these ambivalences on the part of both groups is indicated.

20. Linear algebra

Said-Houari, Belkacem

2017-01-01

This self-contained, clearly written textbook on linear algebra is easily accessible for students. It begins with the simple linear equation and generalizes several notions from this equation for the system of linear equations and introduces the main ideas using matrices. It then offers a detailed chapter on determinants and introduces the main ideas with detailed proofs. The third chapter introduces the Euclidean spaces using very simple geometric ideas and discusses various major inequalities and identities. These ideas offer a solid basis for understanding general Hilbert spaces in functional analysis. The following two chapters address general vector spaces, including some rigorous proofs to all the main results, and linear transformation: areas that are ignored or are poorly explained in many textbooks. Chapter 6 introduces the idea of matrices using linear transformation, which is easier to understand than the usual theory of matrices approach. The final two chapters are more advanced, introducing t...

1. Linear algebra

Stoll, R R

1968-01-01

Linear Algebra is intended to be used as a text for a one-semester course in linear algebra at the undergraduate level. The treatment of the subject will be both useful to students of mathematics and those interested primarily in applications of the theory. The major prerequisite for mastering the material is the readiness of the student to reason abstractly. Specifically, this calls for an understanding of the fact that axioms are assumptions and that theorems are logical consequences of one or more axioms. Familiarity with calculus and linear differential equations is required for understand

2. Analyses of genetic relationships between linear type traits, fat-to-protein ratio, milk production traits, and somatic cell count in first-parity Czech Holstein cows

Zink, V; Zavadilová, L; Lassen, Jan

2014-01-01

. The number of animals for each linear type trait was 59 454, except for locomotion, for which 53 424 animals were recorded. The numbers of animals with records of milk production data were 43 992 for milk yield, fat percentage, protein percentage, and fat-to-protein percentage ratio and 43 978 for fat yield...... and protein yield. In total, 27 098 somatic cell score records were available. The strongest positive genetic correlation between production traits and linear type traits was estimated between udder width and fat yield (0.51 ± 0.04), while the strongest negative correlation estimated was between body......Genetic and phenotypic correlations between production traits, selected linear type traits, and somatic cell score were estimated. The results could be useful for breeding programs involving Czech Holstein dairy cows or other populations. A series of bivariate analyses was applied whereby (co...

3. Linear programming

Solow, Daniel

2014-01-01

This text covers the basic theory and computation for a first course in linear programming, including substantial material on mathematical proof techniques and sophisticated computation methods. Includes Appendix on using Excel. 1984 edition.

4. Linear algebra

Liesen, Jörg

2015-01-01

This self-contained textbook takes a matrix-oriented approach to linear algebra and presents a complete theory, including all details and proofs, culminating in the Jordan canonical form and its proof. Throughout the development, the applicability of the results is highlighted. Additionally, the book presents special topics from applied linear algebra including matrix functions, the singular value decomposition, the Kronecker product and linear matrix equations. The matrix-oriented approach to linear algebra leads to a better intuition and a deeper understanding of the abstract concepts, and therefore simplifies their use in real world applications. Some of these applications are presented in detailed examples. In several ‘MATLAB-Minutes’ students can comprehend the concepts and results using computational experiments. Necessary basics for the use of MATLAB are presented in a short introduction. Students can also actively work with the material and practice their mathematical skills in more than 300 exerc...

5. Linear algebra

Berberian, Sterling K

2014-01-01

Introductory treatment covers basic theory of vector spaces and linear maps - dimension, determinants, eigenvalues, and eigenvectors - plus more advanced topics such as the study of canonical forms for matrices. 1992 edition.

6. Linear Models

Searle, Shayle R

2012-01-01

This 1971 classic on linear models is once again available--as a Wiley Classics Library Edition. It features material that can be understood by any statistician who understands matrix algebra and basic statistical methods.

7. LINEAR ACCELERATOR

Christofilos, N.C.; Polk, I.J.

1959-02-17

Improvements in linear particle accelerators are described. A drift tube system for a linear ion accelerator reduces gap capacity between adjacent drift tube ends. This is accomplished by reducing the ratio of the diameter of the drift tube to the diameter of the resonant cavity. Concentration of magnetic field intensity at the longitudinal midpoint of the external sunface of each drift tube is reduced by increasing the external drift tube diameter at the longitudinal center region.

8. Requirements for existing buildings

Thomsen, Kirsten Engelund; Wittchen, Kim Bjarne

This report collects energy performance requirements for existing buildings in European member states by June 2012.......This report collects energy performance requirements for existing buildings in European member states by June 2012....

9. Greening Existing Tribal Buildings

Guidance about improving sustainability in existing tribal casinos and manufactured homes. Many steps can be taken to make existing buildings greener and healthier. They may also reduce utility and medical costs.

10. The Greenhouse Effect Does Exist!

Ebel, Jochen

2009-01-01

In particular, without the greenhouse effect, essential features of the atmospheric temperature profile as a function of height cannot be described, i.e., the existence of the tropopause above which we see an almost isothermal temperature curve, whereas beneath it the temperature curve is nearly adiabatic. The relationship between the greenhouse effect and observed temperature curve is explained and the paper by Gerlich and Tscheuschner [arXiv:0707.1161] critically analyzed. Gerlich and Tsche...

11. Linear Colliders

Alcaraz, J.

2001-01-01

After several years of study e''+ e''- linear colliders in the TeV range have emerged as the major and optimal high-energy physics projects for the post-LHC era. These notes summarize the present status form the main accelerator and detector features to their physics potential. The LHC era. These notes summarize the present status, from the main accelerator and detector features to their physics potential. The LHC is expected to provide first discoveries in the new energy domain, whereas an e''+ e''- linear collider in the 500 GeV-1 TeV will be able to complement it to an unprecedented level of precision in any possible areas: Higgs, signals beyond the SM and electroweak measurements. It is evident that the Linear Collider program will constitute a major step in the understanding of the nature of the new physics beyond the Standard Model. (Author) 22 refs

12. Linear algebra

Edwards, Harold M

1995-01-01

In his new undergraduate textbook, Harold M Edwards proposes a radically new and thoroughly algorithmic approach to linear algebra Originally inspired by the constructive philosophy of mathematics championed in the 19th century by Leopold Kronecker, the approach is well suited to students in the computer-dominated late 20th century Each proof is an algorithm described in English that can be translated into the computer language the class is using and put to work solving problems and generating new examples, making the study of linear algebra a truly interactive experience Designed for a one-semester course, this text adopts an algorithmic approach to linear algebra giving the student many examples to work through and copious exercises to test their skills and extend their knowledge of the subject Students at all levels will find much interactive instruction in this text while teachers will find stimulating examples and methods of approach to the subject

13. Correlation and simple linear regression.

Zou, Kelly H; Tuncali, Kemal; Silverman, Stuart G

2003-06-01

In this tutorial article, the concepts of correlation and regression are reviewed and demonstrated. The authors review and compare two correlation coefficients, the Pearson correlation coefficient and the Spearman rho, for measuring linear and nonlinear relationships between two continuous variables. In the case of measuring the linear relationship between a predictor and an outcome variable, simple linear regression analysis is conducted. These statistical concepts are illustrated by using a data set from published literature to assess a computed tomography-guided interventional technique. These statistical methods are important for exploring the relationships between variables and can be applied to many radiologic studies.

14. Linear programming

Karloff, Howard

1991-01-01

To this reviewer’s knowledge, this is the first book accessible to the upper division undergraduate or beginning graduate student that surveys linear programming from the Simplex Method…via the Ellipsoid algorithm to Karmarkar’s algorithm. Moreover, its point of view is algorithmic and thus it provides both a history and a case history of work in complexity theory. The presentation is admirable; Karloff's style is informal (even humorous at times) without sacrificing anything necessary for understanding. Diagrams (including horizontal brackets that group terms) aid in providing clarity. The end-of-chapter notes are helpful...Recommended highly for acquisition, since it is not only a textbook, but can also be used for independent reading and study. —Choice Reviews The reader will be well served by reading the monograph from cover to cover. The author succeeds in providing a concise, readable, understandable introduction to modern linear programming. —Mathematics of Computing This is a textbook intend...

15. Heterosis Is a Systemic Property Emerging From Non-linear Genotype-Phenotype Relationships: Evidence From in Vitro Genetics and Computer Simulations

Julie B. Fiévet

2018-05-01

Full Text Available Heterosis, the superiority of hybrids over their parents for quantitative traits, represents a crucial issue in plant and animal breeding as well as evolutionary biology. Heterosis has given rise to countless genetic, genomic and molecular studies, but has rarely been investigated from the point of view of systems biology. We hypothesized that heterosis is an emergent property of living systems resulting from frequent concave relationships between genotypic variables and phenotypes, or between different phenotypic levels. We chose the enzyme-flux relationship as a model of the concave genotype-phenotype (GP relationship, and showed that heterosis can be easily created in the laboratory. First, we reconstituted in vitro the upper part of glycolysis. We simulated genetic variability of enzyme activity by varying enzyme concentrations in test tubes. Mixing the content of “parental” tubes resulted in “hybrids,” whose fluxes were compared to the parental fluxes. Frequent heterotic fluxes were observed, under conditions that were determined analytically and confirmed by computer simulation. Second, to test this model in a more realistic situation, we modeled the glycolysis/fermentation network in yeast by considering one input flux, glucose, and two output fluxes, glycerol and acetaldehyde. We simulated genetic variability by randomly drawing parental enzyme concentrations under various conditions, and computed the parental and hybrid fluxes using a system of differential equations. Again we found that a majority of hybrids exhibited positive heterosis for metabolic fluxes. Cases of negative heterosis were due to local convexity between certain enzyme concentrations and fluxes. In both approaches, heterosis was maximized when the parents were phenotypically close and when the distributions of parental enzyme concentrations were contrasted and constrained. These conclusions are not restricted to metabolic systems: they only depend on the

16. Linear operator inequalities for strongly stable weakly regular linear systems

Curtain, RF

2001-01-01

We consider the question of the existence of solutions to certain linear operator inequalities (Lur'e equations) for strongly stable, weakly regular linear systems with generating operators A, B, C, 0. These operator inequalities are related to the spectral factorization of an associated Popov

17. The linear relationship between the Vulnerable Elders Survey-13 score and mortality in an Asian population of community-dwelling older persons.

Wang, Jye; Lin, Wender; Chang, Ling-Hui

2018-01-01

18. Multiple linear regression approach for the analysis of the relationships between joints mobility and regional pressure-based parameters in the normal-arched foot.

Caravaggi, Paolo; Leardini, Alberto; Giacomozzi, Claudia

2016-10-03

Plantar load can be considered as a measure of the foot ability to transmit forces at the foot/ground, or foot/footwear interface during ambulatory activities via the lower limb kinematic chain. While morphological and functional measures have been shown to be correlated with plantar load, no exhaustive data are currently available on the possible relationships between range of motion of foot joints and plantar load regional parameters. Joints' kinematics from a validated multi-segmental foot model were recorded together with plantar pressure parameters in 21 normal-arched healthy subjects during three barefoot walking trials. Plantar pressure maps were divided into six anatomically-based regions of interest associated to corresponding foot segments. A stepwise multiple regression analysis was performed to determine the relationships between pressure-based parameters, joints range of motion and normalized walking speed (speed/subject height). Sagittal- and frontal-plane joint motion were those most correlated to plantar load. Foot joints' range of motion and normalized walking speed explained between 6% and 43% of the model variance (adjusted R 2 ) for pressure-based parameters. In general, those joints' presenting lower mobility during stance were associated to lower vertical force at forefoot and to larger mean and peak pressure at hindfoot and forefoot. Normalized walking speed was always positively correlated to mean and peak pressure at hindfoot and forefoot. While a large variance in plantar pressure data is still not accounted for by the present models, this study provides statistical corroboration of the close relationship between joint mobility and plantar pressure during stance in the normal healthy foot. Copyright © 2016 Elsevier Ltd. All rights reserved.

19. Introduction to RF linear accelerators

Weiss, M.

1994-01-01

The basic features of RF linear accelerators are described. The concept of the 'loaded cavity', essential for the synchronism wave-particle, is introduced, and formulae describing the action of electromagnetic fields on the beam are given. The treatment of intense beams is mentioned, and various existing linear accelerators are presented as examples. (orig.)

20. Non linear relationship between change in awareness in municipal solid waste management and domestic wastewater management - A case of the Jodipan and Ksatrian village, Malang, East Java

Zakiyya, Nida Maisa; Sarli, Prasanti Widyasih; Soewondo, Prayatni

2017-11-01

In developing countries the awareness on the importance of sanitation facilities, whether it is for municipal solid waste or domestic wastewater treatment, is still very low. Jodipan and Ksatrian Village, in Malang, East Java, are two slum areas that have recently been improved visually by using simple colorful paints. The visual improvement was expected to increase the resident's awareness on the importance of keeping the area clean; adjacent to the project, a new municipal waste management system was also put in place, changing the president's behaviour towards municipal solid waste. This study focuses on the relationship between community awareness in municipal solid waste management and domestic wastewater management. The result is expected to be an input for the government to enhance wastewater infrastructure program and its sustainability, related to its awareness on municipal solid waste. A descriptive model through questionnaire to 48 households of Jodipan sub district in Kampung Warna-warni and 69 households of Ksatrian sub district in Kampung 3D by random sampling, with an error of 0.1, was used to conduct this research. A nonlinear relationship between the change in awareness in municipal solid waste management (MSW) and domestic wastewater management was observed, with only 0.1312 of determination coefficient. Weak Spearman correlation coefficient number was found, ranging from 0.284 to 0.39, indicating another parameter turned into a role on affecting the awareness of wastewater. Further study about another parameter (eg. social and economic parameter) intervension on sanitation awareness could be investigated.

1. Linear programming using Matlab

Ploskas, Nikolaos

2017-01-01

This book offers a theoretical and computational presentation of a variety of linear programming algorithms and methods with an emphasis on the revised simplex method and its components. A theoretical background and mathematical formulation is included for each algorithm as well as comprehensive numerical examples and corresponding MATLAB® code. The MATLAB® implementations presented in this book  are sophisticated and allow users to find solutions to large-scale benchmark linear programs. Each algorithm is followed by a computational study on benchmark problems that analyze the computational behavior of the presented algorithms. As a solid companion to existing algorithmic-specific literature, this book will be useful to researchers, scientists, mathematical programmers, and students with a basic knowledge of linear algebra and calculus.  The clear presentation enables the reader to understand and utilize all components of simplex-type methods, such as presolve techniques, scaling techniques, pivoting ru...

2. A linear relationship between crystal size and fragment binding time observed crystallographically: implications for fragment library screening using acoustic droplet ejection.

Krystal Cole

Full Text Available High throughput screening technologies such as acoustic droplet ejection (ADE greatly increase the rate at which X-ray diffraction data can be acquired from crystals. One promising high throughput screening application of ADE is to rapidly combine protein crystals with fragment libraries. In this approach, each fragment soaks into a protein crystal either directly on data collection media or on a moving conveyor belt which then delivers the crystals to the X-ray beam. By simultaneously handling multiple crystals combined with fragment specimens, these techniques relax the automounter duty-cycle bottleneck that currently prevents optimal exploitation of third generation synchrotrons. Two factors limit the speed and scope of projects that are suitable for fragment screening using techniques such as ADE. Firstly, in applications where the high throughput screening apparatus is located inside the X-ray station (such as the conveyor belt system described above, the speed of data acquisition is limited by the time required for each fragment to soak into its protein crystal. Secondly, in applications where crystals are combined with fragments directly on data acquisition media (including both of the ADE methods described above, the maximum time that fragments have to soak into crystals is limited by evaporative dehydration of the protein crystals during the fragment soak. Here we demonstrate that both of these problems can be minimized by using small crystals, because the soak time required for a fragment hit to attain high occupancy depends approximately linearly on crystal size.

3. Experimental Effects and Individual Differences in Linear Mixed Models: Estimating the Relationship between Spatial, Object, and Attraction Effects in Visual Attention

Kliegl, Reinhold; Wei, Ping; Dambacher, Michael; Yan, Ming; Zhou, Xiaolin

2011-01-01

Linear mixed models (LMMs) provide a still underused methodological perspective on combining experimental and individual-differences research. Here we illustrate this approach with two-rectangle cueing in visual attention (Egly et al., 1994). We replicated previous experimental cue-validity effects relating to a spatial shift of attention within an object (spatial effect), to attention switch between objects (object effect), and to the attraction of attention toward the display centroid (attraction effect), also taking into account the design-inherent imbalance of valid and other trials. We simultaneously estimated variance/covariance components of subject-related random effects for these spatial, object, and attraction effects in addition to their mean reaction times (RTs). The spatial effect showed a strong positive correlation with mean RT and a strong negative correlation with the attraction effect. The analysis of individual differences suggests that slow subjects engage attention more strongly at the cued location than fast subjects. We compare this joint LMM analysis of experimental effects and associated subject-related variances and correlations with two frequently used alternative statistical procedures. PMID:21833292

4. Making sense of enthalpy of vaporization trends for ionic liquids: new experimental and simulation data show a simple linear relationship and help reconcile previous data.

Verevkin, Sergey P; Zaitsau, Dzmitry H; Emel'yanenko, Vladimir N; Yermalayeu, Andrei V; Schick, Christoph; Liu, Hongjun; Maginn, Edward J; Bulut, Safak; Krossing, Ingo; Kalb, Roland

2013-05-30

Vaporization enthalpy of an ionic liquid (IL) is a key physical property for applications of ILs as thermofluids and also is useful in developing liquid state theories and validating intermolecular potential functions used in molecular modeling of these liquids. Compilation of the data for a homologous series of 1-alkyl-3-methylimidazolium bis(trifluoromethane-sulfonyl)imide ([C(n)mim][NTf2]) ILs has revealed an embarrassing disarray of literature results. New experimental data, based on the concurring results from quartz crystal microbalance, thermogravimetric analyses, and molecular dynamics simulation have revealed a clear linear dependence of IL vaporization enthalpies on the chain length of the alkyl group on the cation. Ambiguity of the procedure for extrapolation of vaporization enthalpies to the reference temperature 298 K was found to be a major source of the discrepancies among previous data sets. Two simple methods for temperature adjustment of vaporization enthalpies have been suggested. Resulting vaporization enthalpies obey group additivity, although the values of the additivity parameters for ILs are different from those for molecular compounds.

5. Reduction of Linear Programming to Linear Approximation

Vaserstein, Leonid N.

2006-01-01

It is well known that every Chebyshev linear approximation problem can be reduced to a linear program. In this paper we show that conversely every linear program can be reduced to a Chebyshev linear approximation problem.

6. Perturbed asymptotically linear problems

Bartolo, R.; Candela, A. M.; Salvatore, A.

2012-01-01

The aim of this paper is investigating the existence of solutions of some semilinear elliptic problems on open bounded domains when the nonlinearity is subcritical and asymptotically linear at infinity and there is a perturbation term which is just continuous. Also in the case when the problem has not a variational structure, suitable procedures and estimates allow us to prove that the number of distinct crtitical levels of the functional associated to the unperturbed problem is "stable" unde...

7. Advanced statistics: linear regression, part I: simple linear regression.

Marill, Keith A

2004-01-01

Simple linear regression is a mathematical technique used to model the relationship between a single independent predictor variable and a single dependent outcome variable. In this, the first of a two-part series exploring concepts in linear regression analysis, the four fundamental assumptions and the mechanics of simple linear regression are reviewed. The most common technique used to derive the regression line, the method of least squares, is described. The reader will be acquainted with other important concepts in simple linear regression, including: variable transformations, dummy variables, relationship to inference testing, and leverage. Simplified clinical examples with small datasets and graphic models are used to illustrate the points. This will provide a foundation for the second article in this series: a discussion of multiple linear regression, in which there are multiple predictor variables.

8. Optimization of the time series NDVI-rainfall relationship using linear mixed-effects modeling for the anti-desertification area in the Beijing and Tianjin sandstorm source region

Wang, Jin; Sun, Tao; Fu, Anmin; Xu, Hao; Wang, Xinjie

2018-05-01

Degradation in drylands is a critically important global issue that threatens ecosystem and environmental in many ways. Researchers have tried to use remote sensing data and meteorological data to perform residual trend analysis and identify human-induced vegetation changes. However, complex interactions between vegetation and climate, soil units and topography have not yet been considered. Data used in the study included annual accumulated Moderate Resolution Imaging Spectroradiometer (MODIS) 250 m normalized difference vegetation index (NDVI) from 2002 to 2013, accumulated rainfall from September to August, digital elevation model (DEM) and soil units. This paper presents linear mixed-effect (LME) modeling methods for the NDVI-rainfall relationship. We developed linear mixed-effects models that considered the random effects of sample points nested in soil units for nested two-level modeling and single-level modeling of soil units and sample points, respectively. Additionally, three functions, including the exponential function (exp), the power function (power), and the constant plus power function (CPP), were tested to remove heterogeneity, and an additional three correlation structures, including the first-order autoregressive structure [AR(1)], a combination of first-order autoregressive and moving average structures [ARMA(1,1)] and the compound symmetry structure (CS), were used to address the spatiotemporal correlations. It was concluded that the nested two-level model considering both heteroscedasticity with (CPP) and spatiotemporal correlation with [ARMA(1,1)] showed the best performance (AMR = 0.1881, RMSE = 0.2576, adj- R 2 = 0.9593). Variations between soil units and sample points that may have an effect on the NDVI-rainfall relationship should be included in model structures, and linear mixed-effects modeling achieves this in an effective and accurate way.

9. Relationship between neighbourhood socioeconomic position and neighbourhood public green space availability: An environmental inequality analysis in a large German city applying generalized linear models.

Schüle, Steffen Andreas; Gabriel, Katharina M A; Bolte, Gabriele

2017-06-01

10. Red Shifts and Existing Speculations

Aisenberg, Sol

2009-03-01

There are many current flaws, mysteries, and errors in the standard model of the universe - all based upon speculative interpretation of many excellent and verified observations. The most serious cause of some errors is the speculation about the meaning of the redshifts observed in the 1930s by Hubble. He ascribed the redshifts as due to an apparent Doppler effect''. This led to speculation that the remote stars were receding, and the universe was expanding -- although without observational proof of the actual receding velocity of the stars. The age of the universe, based upon the Hubble constant is pure speculation because of lack of velocity demonstration. The belief in expansion, the big bang, and of inflation should be reexamined. Also, the redshift cannot always be used as a distance measure, particularly for photons from quasars containing massive black holes that can reduce photon energy through gravitational attraction. If the linear Hubble constant is extrapolated to the most remote super novae and beyond, it would eventually require that the corresponding photon energy go to zero or become negative -- according to Hubble linear relationship. This should require a reexamination of the meaning of the red shift and the speculative consequences and give a model with fewer mysteries.

11. Estimating kinetic mechanisms with prior knowledge I: Linear parameter constraints.

Salari, Autoosa; Navarro, Marco A; Milescu, Mirela; Milescu, Lorin S

2018-02-05

To understand how ion channels and other proteins function at the molecular and cellular levels, one must decrypt their kinetic mechanisms. Sophisticated algorithms have been developed that can be used to extract kinetic parameters from a variety of experimental data types. However, formulating models that not only explain new data, but are also consistent with existing knowledge, remains a challenge. Here, we present a two-part study describing a mathematical and computational formalism that can be used to enforce prior knowledge into the model using constraints. In this first part, we focus on constraints that enforce explicit linear relationships involving rate constants or other model parameters. We develop a simple, linear algebra-based transformation that can be applied to enforce many types of model properties and assumptions, such as microscopic reversibility, allosteric gating, and equality and inequality parameter relationships. This transformation converts the set of linearly interdependent model parameters into a reduced set of independent parameters, which can be passed to an automated search engine for model optimization. In the companion article, we introduce a complementary method that can be used to enforce arbitrary parameter relationships and any constraints that quantify the behavior of the model under certain conditions. The procedures described in this study can, in principle, be coupled to any of the existing methods for solving molecular kinetics for ion channels or other proteins. These concepts can be used not only to enforce existing knowledge but also to formulate and test new hypotheses. © 2018 Salari et al.

12. Use of linear free energy relationship to predict Gibbs free energies of formation of zirconolite phases (MZrTi2O7 and MHfTi2O7)

Xu, H.

1999-01-01

In this letter, the Sverjensky-Molling equation derived from a linear free energy relationship is used to calculate the Gibbs free energies of formation of zirconolite crystalline phases (MZrTi 2 O 7 and MHfTi 2 O 7 ) from the known thermodynamic properties of the corresponding aqueous divalent cations (M 2+ ). Sverjensky-Molling equation is expressed as ΔG 0 f,M v X =a M v X ΔG 0 n,M 2+ +b M v X +β M v X r M 2+ , where the coefficients a M v X , b M v X , and β M v X characterize a particular structural family of M v X, r M 2+ is the ionic radius of M 2+ cation, ΔG f,M v X 0 is the standard Gibbs free energy of formation of M v X, and ΔG 0 n,M 2+ is the standard non-solvation energy of cation M 2+ . This relationship can be used to predict the Gibbs free energies of formation of various fictive phases (such as BaZrTi 2 O 7 , SrZrTi 2 O 7 , PbZrTi 2 O 7 , etc.) that may form solid solution with CaZrTi 2 O 7 in actual Synroc-based nuclear waste forms. Based on obtained linear free energy relationships, it is predicted that large cations (e.g., Ba and Ra) prefer to be in perovskite structure, and small cations (e.g., Ca, Zn, and Cd) prefer to be in zirconolite structure. (orig.)

13. Why preeclampsia still exists?

Chelbi, Sonia T; Veitia, Reiner A; Vaiman, Daniel

2013-08-01

Preeclampsia (PE) is a deadly gestational disease affecting up to 10% of women and specific of the human species. Preeclampsia is clearly multifactorial, but the existence of a genetic basis for this disease is now clearly established by the existence of familial cases, epidemiological studies and known predisposing gene polymorphisms. PE is very common despite the fact that Darwinian pressure should have rapidly eliminated or strongly minimized the frequency of predisposing alleles. Consecutive pregnancies with the same partner decrease the risk and severity of PE. Here, we show that, due to this peculiar feature, preeclampsia predisposing-alleles can be differentially maintained according to the familial structure. Thus, we suggest that an optimal frequency of PE-predisposing alleles in human populations can be achieved as a result of a trade-off between benefits of exogamy, importance for maintaining genetic diversity and increase of the fitness owing to a stable paternal investment. Copyright © 2013 Elsevier Ltd. All rights reserved.

14. Existence of Projective Planes

Perrott, Xander

2016-01-01

This report gives an overview of the history of finite projective planes and their properties before going on to outline the proof that no projective plane of order 10 exists. The report also investigates the search carried out by MacWilliams, Sloane and Thompson in 1970 [12] and confirms their result by providing independent verification that there is no vector of weight 15 in the code generated by the projective plane of order 10.

15. Does bioethics exist?

Turner, L

2009-12-01

Bioethicists disagree over methods, theories, decision-making guides, case analyses and public policies. Thirty years ago, the thinking of many scholars coalesced around a principlist approach to bioethics. That mid-level mode of moral reasoning is now one of many approaches to moral deliberation. Significant variation in contemporary approaches to the study of ethical issues related to medicine, biotechnology and health care raises the question of whether bioethics exists as widely shared method, theory, normative framework or mode of moral reasoning.

Tanwiwat Jaikuna

2017-02-01

Full Text Available Purpose: To develop an in-house software program that is able to calculate and generate the biological dose distribution and biological dose volume histogram by physical dose conversion using the linear-quadratic-linear (LQL model. Material and methods : The Isobio software was developed using MATLAB version 2014b to calculate and generate the biological dose distribution and biological dose volume histograms. The physical dose from each voxel in treatment planning was extracted through Computational Environment for Radiotherapy Research (CERR, and the accuracy was verified by the differentiation between the dose volume histogram from CERR and the treatment planning system. An equivalent dose in 2 Gy fraction (EQD2 was calculated using biological effective dose (BED based on the LQL model. The software calculation and the manual calculation were compared for EQD2 verification with pair t-test statistical analysis using IBM SPSS Statistics version 22 (64-bit. Results: Two and three-dimensional biological dose distribution and biological dose volume histogram were displayed correctly by the Isobio software. Different physical doses were found between CERR and treatment planning system (TPS in Oncentra, with 3.33% in high-risk clinical target volume (HR-CTV determined by D90%, 0.56% in the bladder, 1.74% in the rectum when determined by D2cc, and less than 1% in Pinnacle. The difference in the EQD2 between the software calculation and the manual calculation was not significantly different with 0.00% at p-values 0.820, 0.095, and 0.593 for external beam radiation therapy (EBRT and 0.240, 0.320, and 0.849 for brachytherapy (BT in HR-CTV, bladder, and rectum, respectively. Conclusions : The Isobio software is a feasible tool to generate the biological dose distribution and biological dose volume histogram for treatment plan evaluation in both EBRT and BT.

17. Periodic orbits from Δ-modulation of stable linear systems

Xia, X.; Zinober, A.

2004-01-01

The Î�-modulated control of a single input, discrete time, linear stable system is investigated. The modulation direction is given by cTx where c â��Rn/{0} is a given, otherwise arbitrary, vector. We obtain necessary and sufficient conditions for the existence of periodic points of a finite order. Some concrete results about the existence of a certain order of periodic points are also derived. We also study the relationship between certain polyhedra and the periodicity of the Î�-modulated orb...

18. Evaluation of the linearity of soft- to hard-tissue movement after orthognathic surgery

Chew, Ming Tak; Sandham, John; Wong, Hwee Bee

2008-01-01

Introduction: Our aim in this study was to investigate whether a linear relationship exists between soft- to hard-tissue changes for both maxillary and mandibular landmarks over a wide range of skeletal changes. Methods: The sample consisted of 30 Chinese patients with Class III malocclusion treated

19. Evaluation of the linearity of soft- to hard-tissue movement after orthognathic surgery

Chew, Ming Tak; Sandham, John; Wong, Hwee Bee

Introduction: Our aim in this study was to investigate whether a linear relationship exists between soft- to hard-tissue changes for both maxillary and mandibular landmarks over a wide range of skeletal changes. Methods: The sample consisted of 30 Chinese patients with Class III malocclusion treated

20. Distributed lags time series analysis versus linear correlation analysis (Pearson's r) in identifying the relationship between antipseudomonal antibiotic consumption and the susceptibility of Pseudomonas aeruginosa isolates in a single Intensive Care Unit of a tertiary hospital.

Erdeljić, Viktorija; Francetić, Igor; Bošnjak, Zrinka; Budimir, Ana; Kalenić, Smilja; Bielen, Luka; Makar-Aušperger, Ksenija; Likić, Robert

2011-05-01

The relationship between antibiotic consumption and selection of resistant strains has been studied mainly by employing conventional statistical methods. A time delay in effect must be anticipated and this has rarely been taken into account in previous studies. Therefore, distributed lags time series analysis and simple linear correlation were compared in their ability to evaluate this relationship. Data on monthly antibiotic consumption for ciprofloxacin, piperacillin/tazobactam, carbapenems and cefepime as well as Pseudomonas aeruginosa susceptibility were retrospectively collected for the period April 2006 to July 2007. Using distributed lags analysis, a significant temporal relationship was identified between ciprofloxacin, meropenem and cefepime consumption and the resistance rates of P. aeruginosa isolates to these antibiotics. This effect was lagged for ciprofloxacin and cefepime [1 month (R=0.827, P=0.039) and 2 months (R=0.962, P=0.001), respectively] and was simultaneous for meropenem (lag 0, R=0.876, P=0.002). Furthermore, a significant concomitant effect of meropenem consumption on the appearance of multidrug-resistant P. aeruginosa strains (resistant to three or more representatives of classes of antibiotics) was identified (lag 0, R=0.992, PPearson's correlation coefficient. Correlation coefficient analysis was not able to identify relationships between antibiotic consumption and bacterial resistance when the effect was delayed. These results indicate that the use of diverse statistical methods can yield significantly different results, thus leading to the introduction of possibly inappropriate infection control measures. Copyright © 2010 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

1. Evaluate existing radiation fields

Aldrich, J.M.; Haggard, D.L.; Endres, G.W.R.; Fix, J.J.

1981-01-01

Knowledge of the spectrum of energies for beta, gamma, and neutron radiation experienced in the field is crucial to the proper interpretation of personnel dose. Calibration sources and techniques are determined on the basis of their relationship to field exposure. Selected techniques were used to obtain neutron, photon, and beta energy spectra data at several Hanford locations. Four neutron energy spectra and dose measurement methods were used: (1) multisphere spectrometer system; (2) tissue equivalent proportional counter (TEPC); (3) RASCAL (9'' to 3'' sphere ratios); and (4) helium-3 neutron spectrometer. Gamma spectroscopy was done using standard techniques. A specially designed TLD dosimeter was used to obtain beta spectrum measurements. The design and use of each of these instruments is described in the body of this report. Data collected and analyzed for each of the Hanford locations are included

2. O Ponto G Existe?

Carlos Alexandre Molina Noccioli

2016-07-01

Full Text Available Este trabalho busca analisar o tratamento linguístico-discursivo das informações acerca de um tópicotemático tradicionalmente visto como tabu, relacionado a questões sexuais, na notícia O ponto G existe?, publicada em 2008, na revista brasileira Superinteressante, destacando-se como o conhecimento em questão é representado socialmente ao se considerar a linha editorial da revista. A notícia caracteriza-se como um campo fértil para a análise das estratégias divulgativas, já que atrai, inclusive pelas escolhas temáticas, a curiosidade dos leitores. Imbuído de um tema excêntrico, o texto consegue angariar um público jovem interessado em discussões polêmicas relacionadas ao seu universo.

3. Lebesgue Sets Immeasurable Existence

Diana Marginean Petrovai

2012-12-01

Full Text Available It is well known that the notion of measure and integral were released early enough in close connection with practical problems of measuring of geometric ﬁgures. Notion of measure was outlined in the early 20th century through H. Lebesgue’s research, founder of the modern theory of measure and integral. It was developed concurrently a technique of integration of functions. Gradually it was formed a speciﬁc area todaycalled the measure and integral theory. Essential contributions to building this theory was made by a large number of mathematicians: C. Carathodory, J. Radon, O. Nikodym, S. Bochner, J. Pettis, P. Halmos and many others. In the following we present several abstract sets, classes of sets. There exists the sets which are not Lebesgue measurable and the sets which are Lebesgue measurable but are not Borel measurable. Hence B ⊂ L ⊂ P(X.

4. EXIST Perspective for SFXTs

Ubertini, Pietro; Sidoli, L.; Sguera, V.; Bazzano, A.

2009-12-01

Supergiant Fast X-ray Transients (SFXTs) are one of the most interesting (and unexpected) results of the INTEGRAL mission. They are a new class of HMXBs displaying short hard X-ray outbursts (duration less tha a day) characterized by fast flares (few hours timescale) and large dinamic range (10E3-10E4). The physical mechanism driving their peculiar behaviour is still unclear and highly debated: some models involve the structure of the supergiant companion donor wind (likely clumpy, in a spherical or non spherical geometry) and the orbital properties (wide separation with eccentric or circular orbit), while others involve the properties of the neutron star compact object and invoke very low magnetic field values (B 1E14 G, magnetars). The picture is still highly unclear from the observational point of view as well: no cyclotron lines have been detected in the spectra, thus the strength of the neutron star magnetic field is unknown. Orbital periods have been measured in only 4 systems, spanning from 3.3 days to 165 days. Even the duty cycle seems to be quite different from source to source. The Energetic X-ray Imaging Survey Telescope (EXIST), with its hard X-ray all-sky survey and large improved limiting sensitivity, will allow us to get a clearer picture of SFXTs. A complete census of their number is essential to enlarge the sample. A long term and continuous as possible X-ray monitoring is crucial to -(1) obtain the duty cycle, -(2 )investigate their unknown orbital properties (separation, orbital period, eccentricity),- (3) to completely cover the whole outburst activity, (4)-to search for cyclotron lines in the high energy spectra. EXIST observations will provide crucial informations to test the different models and shed light on the peculiar behaviour of SFXTs.

5. Ancestral Relationships Using Metafounders

Legarra, Andres; Christensen, Ole Fredslund; Vitezica, Zulma G

2015-01-01

Recent use of genomic (marker-based) relationships shows that relationships exist within and across base population (breeds or lines). However, current treatment of pedigree relationships is unable to consider relationships within or across base populations, although such relationships must exist...

6. The development of a non-linear autoregressive model with exogenous input (NARX) to model climate-water clarity relationships: reconstructing a historical water clarity index for the coastal waters of the southeastern USA

Lee, Cameron C.; Sheridan, Scott C.; Barnes, Brian B.; Hu, Chuanmin; Pirhalla, Douglas E.; Ransibrahmanakul, Varis; Shein, Karsten

2017-10-01

The coastal waters of the southeastern USA contain important protected habitats and natural resources that are vulnerable to climate variability and singular weather events. Water clarity, strongly affected by atmospheric events, is linked to substantial environmental impacts throughout the region. To assess this relationship over the long-term, this study uses an artificial neural network-based time series modeling technique known as non-linear autoregressive models with exogenous input (NARX models) to explore the relationship between climate and a water clarity index (KDI) in this area and to reconstruct this index over a 66-year period. Results show that synoptic-scale circulation patterns, weather types, and precipitation all play roles in impacting water clarity to varying degrees in each region of the larger domain. In particular, turbid water is associated with transitional weather and cyclonic circulation in much of the study region. Overall, NARX model performance also varies—regionally, seasonally and interannually—with wintertime estimates of KDI along the West Florida Shelf correlating to the actual KDI at r > 0.70. Periods of extreme (high) KDI in this area coincide with notable El Niño events. An upward trend in extreme KDI events from 1948 to 2013 is also present across much of the Florida Gulf coast.

7. Linear Algebra and Smarandache Linear Algebra

Vasantha, Kandasamy

2003-01-01

The present book, on Smarandache linear algebra, not only studies the Smarandache analogues of linear algebra and its applications, it also aims to bridge the need for new research topics pertaining to linear algebra, purely in the algebraic sense. We have introduced Smarandache semilinear algebra, Smarandache bilinear algebra and Smarandache anti-linear algebra and their fuzzy equivalents. Moreover, in this book, we have brought out the study of linear algebra and vector spaces over finite p...

8. TENSOR DECOMPOSITIONS AND SPARSE LOG-LINEAR MODELS

Johndrow, James E.; Bhattacharya, Anirban; Dunson, David B.

2017-01-01

Contingency table analysis routinely relies on log-linear models, with latent structure analysis providing a common alternative. Latent structure models lead to a reduced rank tensor factorization of the probability mass function for multivariate categorical data, while log-linear models achieve dimensionality reduction through sparsity. Little is known about the relationship between these notions of dimensionality reduction in the two paradigms. We derive several results relating the support of a log-linear model to nonnegative ranks of the associated probability tensor. Motivated by these findings, we propose a new collapsed Tucker class of tensor decompositions, which bridge existing PARAFAC and Tucker decompositions, providing a more flexible framework for parsimoniously characterizing multivariate categorical data. Taking a Bayesian approach to inference, we illustrate empirical advantages of the new decompositions. PMID:29332971

9. Chemical composition of the essential oils of Citrus sinensis cv. valencia and a quantitative structure-retention relationship study for the prediction of retention indices by multiple linear regression

Larijani Kambiz

2011-01-01

Full Text Available The chemical composition of the volatile fraction obtained by head-space solid phase microextraction (HS-SPME, single drop microextraction (SDME and the essential oil obtained by cold-press from the peels of C. sinensis cv. valencia were analyzed employing gas chromatography-flame ionization detector (GC-FID and gas chromatography-mass spectrometry (GC-MS. The main components were limonene (61.34 %, 68.27 %, 90.50 %, myrcene (17.55 %, 12.35 %, 2.50 %, sabinene (6.50 %, 7.62 %, 0.5 % and α-pinene (0 %, 6.65 %, 1.4 % respectively obtained by HS-SPME, SDME and cold-press. Then a quantitative structure-retention relationship (QSRR study for the prediction of retention indices (RI of the compounds was developed by application of structural descriptors and the multiple linear regression (MLR method. Principal components analysis was used to select the training set. A simple model with low standard errors and high correlation coefficients was obtained. The results illustrated that linear techniques such as MLR combined with a successful variable selection procedure are capable of generating an efficient QSRR model for prediction of the retention indices of different compounds. This model, with high statistical significance (R2 train = 0.983, R2 test = 0.970, Q2 LOO = 0.962, Q2 LGO = 0.936, REP(% = 3.00, could be used adequately for the prediction and description of the retention indices of the volatile compounds.

10. LINEAR2007, Linear-Linear Interpolation of ENDF Format Cross-Sections

2007-01-01

1 - Description of program or function: LINEAR converts evaluated cross sections in the ENDF/B format into a tabular form that is subject to linear-linear interpolation in energy and cross section. The code also thins tables of cross sections already in that form. Codes used subsequently need thus to consider only linear-linear data. IAEA1311/15: This version include the updates up to January 30, 2007. Changes in ENDF/B-VII Format and procedures, as well as the evaluations themselves, make it impossible for versions of the ENDF/B pre-processing codes earlier than PREPRO 2007 (2007 Version) to accurately process current ENDF/B-VII evaluations. The present code can handle all existing ENDF/B-VI evaluations through release 8, which will be the last release of ENDF/B-VI. Modifications from previous versions: - Linear VERS. 2007-1 (JAN. 2007): checked against all ENDF/B-VII; increased page size from 60,000 to 600,000 points 2 - Method of solution: Each section of data is considered separately. Each section of File 3, 23, and 27 data consists of a table of cross section versus energy with any of five interpolation laws. LINEAR will replace each section with a new table of energy versus cross section data in which the interpolation law is always linear in energy and cross section. The histogram (constant cross section between two energies) interpolation law is converted to linear-linear by substituting two points for each initial point. The linear-linear is not altered. For the log-linear, linear-log and log- log laws, the cross section data are converted to linear by an interval halving algorithm. Each interval is divided in half until the value at the middle of the interval can be approximated by linear-linear interpolation to within a given accuracy. The LINEAR program uses a multipoint fractional error thinning algorithm to minimize the size of each cross section table

11. Linear quadratic optimization for positive LTI system

Muhafzan, Yenti, Syafrida Wirma; Zulakmal

2017-05-01

Nowaday the linear quadratic optimization subject to positive linear time invariant (LTI) system constitute an interesting study considering it can become a mathematical model of variety of real problem whose variables have to nonnegative and trajectories generated by these variables must be nonnegative. In this paper we propose a method to generate an optimal control of linear quadratic optimization subject to positive linear time invariant (LTI) system. A sufficient condition that guarantee the existence of such optimal control is discussed.

12. 本土化人格特质与工作绩效的关系：线性与非线性%The Relationships between Indigenous Personality Traits and Job Performance: Linear and Nonlinear

张珊珊; 周明洁; 陈爽; 张建新

2012-01-01

Chinese personality traits have unique differences from other cultures due to China's special geography and collectivist cultural background. Therefore, the philosophy of localization was accepted and advocated by more and more Chinese psychologists. Meanwhile, the nonlinear relationships between personality traits and job performance have been found in some studies. These results transformed the traditional top - down strategy into double strategies for the applications of personality tests in the psychology of personnel management. However, there was no research to combine the linear and nonlinear models to examine the relationships between indigenous personality traits and job performance in the Chinese work setting. In the current study, we explored the linear and/or nonlinear reationships between indigenous personality traits and job performance. The participants were 182 service employees from several service industries in Beijing, and the immediate supervisors of the respondents provided ratings of their job performance and returned independently to the interviewers. The ratings of job performance were self - compiled based on job analysis and in - depth interview. Confirmatory factor analysis found that the one - factor performance model had a better fit (χ2 = 27.79, df = 8, CFI = . 95, NF1 = . 93, RMSEA = . 07), and the coefficient alpha was . 85. Meanwhile, the nine subscales from CPAI -2 were selected to assess the indigenous personality traits: face (FAC), family orientation (FAM), defensiveness (DEF), graciousness vs. meanness (G_M), veraciousness vs. slickness (V_S), traditionalism vs. modernity (T_M), renqing (REN), harmony (HAR) and thrift vs. extravagance (T_E). The mean Cronbach's coefficient for the entire set of personality scales was . 70 in the representative normal sample in Chinese mainland and Hong Kong. The data were analyzed with SPSS 15.0, and the main statistical methods were correlation analysis and hierarchical polynomial regression

13. Linear free energy relationships in heterogeneous catalysis--13. The dehydration of aliphatic alcohols over silica-alumina. [N-butyl alcohol, sec. -butyl or isopropyl alcohol, tert. -butyl alcolol

Take, J; Matsumoto, T; Yoneda, Y

1978-01-01

The dehydration of n-butyl alcohol at 120/sup 0/-166/sup 0/C, sec.-butyl or isopropyl alcohol at 100/sup 0/-145/sup 0/C, and tert.-butyl alcohol at 54/sup 0/-80/sup 0/C, over silica/alumina catalyst was zero order in alcohol at 0.01-0.1 atm, and the activation energies were 35.3, 31.7, 32.0, and 29.9 kcal/mol, respectively. The zero-order rate constants were mainly affected by the activation energies since the preexponential factors varied little except for tert.-butyl alcohol. A linear relationship was found between the activation energy or the logarithm of the zero-order rate constant and the heterolytic bond dissociation energy for the carbon-oxygen bond in alcohols D(R/sup +/OH/sup -/). The activation energy increased and the rate constant decreased with increasing D(R/sup +/OH/sup -/). The results indicate that dehydration is E1 over this catalyst, but a similar correlation was observed based on published data for dehydration over alumina, which follows an E2 mechanism, indicating that heterolytic cleavage of the C-O bond is rate-determining in both mechanisms.

14. Ascent, descent, nullity, defect, and related notions for linear relations in linear spaces

Sandovici, Adrian; de Snoo, Henk; Winkler, Henrik

2007-01-01

For a linear relation in a linear space the concepts of ascent, descent, nullity, and defect are introduced and studied. It is shown that the results of A.E. Taylor and M.A. Kaashoek concerning the relationship between ascent, descent, nullity, and defect for the case of linear operators remain

15. Pancreatic beta cell function increases in a linear dose-response manner following exercise training in adults with prediabetes

Malin, Steven K; Solomon, Thomas; Blaszczak, Alecia

2013-01-01

While some studies suggest that a linear dose-response relationship exists between exercise and insulin sensitivity, the exercise dose required to enhance pancreatic beta-cell function is unknown. Thirty-five older, obese adults with prediabetes underwent a progressive 12-week supervised exercise...

16. Linear wind generator

Kozarov, A.; Petrov, O.; Antonov, J.; Sotirova, S.; Petrova, B.

2006-01-01

The purpose of the linear wind-power generator described in this article is to decrease the following disadvantages of the common wind-powered turbine: 1) large bending and twisting moments to the blades and the shaft, especially when strong winds and turbulence exist; 2) significant values of the natural oscillation period of the construction result in the possibility of occurrence of destroying resonance oscillations; 3) high velocity of the peripheral parts of the rotor creating a danger for birds; 4) difficulties, connected with the installation and the operation on the mountain ridges and passages where the wind energy potential is the largest. The working surfaces of the generator in questions driven by the wind are not connected with a joint shaft but each moves along a railway track with few oscillations. So the sizes of each component are small and their number can be rather large. The mechanical trajectory is not a circle but a closed outline in a vertical plain, which consists of two rectilinear sectors, one above the other, connected in their ends by semi-circumferences. The mechanical energy of each component turns into electrical on the principle of the linear electrical generator. A regulation is provided when the direction of the wind is perpendicular to the route. A possibility of effectiveness is shown through aiming of additional quantities of air to the movable components by static barriers

17. Linearly constrained minimax optimization

Madsen, Kaj; Schjær-Jacobsen, Hans

1978-01-01

We present an algorithm for nonlinear minimax optimization subject to linear equality and inequality constraints which requires first order partial derivatives. The algorithm is based on successive linear approximations to the functions defining the problem. The resulting linear subproblems...

18. What can dissaving tell us about catastrophic costs? Linear and logistic regression analysis of the relationship between patient costs and financial coping strategies adopted by tuberculosis patients in Bangladesh, Tanzania and Bangalore, India.

Madan, Jason; Lönnroth, Knut; Laokri, Samia; Squire, Stephen Bertel

2015-10-22

Tuberculosis (TB) is a major global public health problem which affects poorest individuals the worst. A high proportion of patients incur 'catastrophic costs' which have been shown to result in severe financial hardship and adverse health outcomes. Data on catastrophic cost incidence is not routinely collected, and current definitions of this indicator involve several practical and conceptual barriers to doing so. We analysed data from TB programmes in India (Bangalore), Bangladesh and Tanzania to determine whether dissaving (the sale of assets or uptake of loans) is a useful indicator of financial hardship. Data were obtained from prior studies of TB patient costs in Bangladesh (N = 96), Tanzania (N = 94) and Bangalore (N = 891). These data were analysed using logistic and linear multivariate regression to determine the association between costs (absolute and relative to income) and both the presence of dissaving and the amounts dissaved. After adjusting for covariates such as age, sex and rural/urban location, we found a significant positive association between the occurrence of dissaving and total costs incurred in Tanzania and Bangalore. We further found that, for patients in Bangalore an increase in dissaving of $10 USD was associated with an increase in the cost-income ratio of 0.10 (p costs of$7 USD (p costs that does not require usage of complex patient cost questionnaires. It also offers an informative indicator of financial hardship in its own right, and could therefore play an important role as an indicator to monitor and evaluate the impact of financial protection and service delivery interventions in reducing hardship and facilitating universal health coverage. Further research is required to understand the patterns and types of dissaving that have the strongest relationship with financial hardship and clinical outcomes in order to move toward evidence-based policy making.

19. Foundations of linear and generalized linear models

Agresti, Alan

2015-01-01

A valuable overview of the most important ideas and results in statistical analysis Written by a highly-experienced author, Foundations of Linear and Generalized Linear Models is a clear and comprehensive guide to the key concepts and results of linear statistical models. The book presents a broad, in-depth overview of the most commonly used statistical models by discussing the theory underlying the models, R software applications, and examples with crafted models to elucidate key ideas and promote practical model building. The book begins by illustrating the fundamentals of linear models,

20. How many N = 4 strings exist?

Ketov, S.V.

1994-09-01

Possible ways of constructing extended fermionic strings with N=4 world-sheet supersymmetry are reviewed. String theory constraints form, in general, a non-linear quasi(super)conformal algebra, and can have conformal dimensions ≥1. When N=4, the most general N=4 quasi-superconformal algebra to consider for string theory building is D(1, 2; α), whose linearisation is the so-called ''large'' N=4 superconformal algebra. The D(1, 2; α) algebra has su(2)sub(κ + )+su(2)sub(κ - )+u(1) Kac-Moody component, and α=κ - /κ + . We check the Jacobi identities and construct a BRST charge for the D(1, 2; α) algebra. The quantum BRST operator can be made nilpotent only when κ + =κ - =-2. The D(1, 2; 1) algebra is actually isomorphic to the SO(4)-based Bershadsky-Knizhnik non-linear quasi-superconformal algebra. We argue about the existence of a string theory associated with the latter, and propose the (non-covariant) hamiltonian action for this new N=4 string theory. Our results imply the existence of two different N=4 fermionic string theories: the old one based on the ''small'' linear N=4 superconformal algebra and having the total ghost central charge c gh =+12, and the new one with non-linearly realised N=4 supersymmetry, based on the SO(4) quasi-superconformal algebra and having c gh =+6. Both critical string theories have negative ''critical dimensions'' and do not admit unitary matter representations. (orig.)

1. Transgender Parenting: A Review of Existing Research

Stotzer, Rebecca L; Herman, Jody L; Hasenbush, Amira

2014-01-01

The authors of this report reviewed 51 studies that analyze data about transgender parents. This report reviews the existing research on the prevalence and characteristics of transgender people who are parents, the quality of relationships between transgender parents and their children, outcomes for children with a transgender parent, and the reported needs of transgender parents. Overall, the authors found that substantial numbers of transgender people are parents, though at rates below the ...

2. Relationship of Estuarine Plant Contaminants to Existing Data Bases

1988-02-01

shipyards. 3) Mouriscas - located near the old tidal-mill of Quinta das Mouriscas, a few Km west of the Aguas de Moura channel. The fine sediments...globulus) from natural (mean values) and industrialized areas (maximum values) in the Chile coast. (Gonzilez & Bergqvist, 1986). NATURAL HEAVILY...Sector del Secano Costero de Ia V Re- gion. Agricultura Tecnica ( Chile ), 46: 299-306. HARDIMAN, R.T., Banin, A. & Jacoby, B. (1984). The Effect of Soil

3. Asymmetries exist in the Feldstein-Horioka relationship

Raza, Hamid; Zoega, Gylfi; Kinsella, Stephen

2017-01-01

Most studies assume symmetry between saving and investment changes. They are wrong to do so. We model the response of investment to positive and negative changes in saving for 17 OECD countries from 1960 to 2015. We use both panel and time series methods. We find that negative changes in saving h...... run are called into question. Policies assuming symmetric effects throughout the business cycle are similarly flawed....

4. On deformations of linear differential systems

Gontsov, R.R.; Poberezhnyi, V.A.; Helminck, G.F.

2011-01-01

This article concerns deformations of meromorphic linear differential systems. Problems relating to their existence and classification are reviewed, and the global and local behaviour of solutions to deformation equations in a neighbourhood of their singular set is analysed. Certain classical

5. Nonlinear dynamics between linear and impact limits

Pilipchuk, Valery N; Wriggers, Peter

2010-01-01

This book examines nonlinear dynamic analyses based on the existence of strongly nonlinear but simple counterparts to the linear models and tools. Discusses possible application to periodic elastic structures with non-smooth or discontinuous characteristics.

6. Advanced statistics: linear regression, part II: multiple linear regression.

Marill, Keith A

2004-01-01

The applications of simple linear regression in medical research are limited, because in most situations, there are multiple relevant predictor variables. Univariate statistical techniques such as simple linear regression use a single predictor variable, and they often may be mathematically correct but clinically misleading. Multiple linear regression is a mathematical technique used to model the relationship between multiple independent predictor variables and a single dependent outcome variable. It is used in medical research to model observational data, as well as in diagnostic and therapeutic studies in which the outcome is dependent on more than one factor. Although the technique generally is limited to data that can be expressed with a linear function, it benefits from a well-developed mathematical framework that yields unique solutions and exact confidence intervals for regression coefficients. Building on Part I of this series, this article acquaints the reader with some of the important concepts in multiple regression analysis. These include multicollinearity, interaction effects, and an expansion of the discussion of inference testing, leverage, and variable transformations to multivariate models. Examples from the first article in this series are expanded on using a primarily graphic, rather than mathematical, approach. The importance of the relationships among the predictor variables and the dependence of the multivariate model coefficients on the choice of these variables are stressed. Finally, concepts in regression model building are discussed.

7. Ontological Proofs of Existence and Non-Existence

Hájek, Petr

2008-01-01

Roč. 90, č. 2 (2008), s. 257-262 ISSN 0039-3215 R&D Projects: GA AV ČR IAA100300503 Institutional research plan: CEZ:AV0Z10300504 Keywords : ontological proofs * existence * non-existence * Gödel * Caramuel Subject RIV: BA - General Mathematics

8. Global existence of small solutions to semilinear Schroedinger equations

Chihara, Hiroyuki

1996-01-01

We present global existence theorem for semilinear Schrodinger equations. In general, Schrodinger-type equations do not admit the classical energy estimates. To avoid this difficulty, we use S. Doi's method for linear Schrodinger-type equations. Combining his method and L p -L q estimates, we prove the global existence of solutions with small initial data

9. Simplified Linear Equation Solvers users manual

Gropp, W. [Argonne National Lab., IL (United States); Smith, B. [California Univ., Los Angeles, CA (United States)

1993-02-01

The solution of large sparse systems of linear equations is at the heart of many algorithms in scientific computing. The SLES package is a set of easy-to-use yet powerful and extensible routines for solving large sparse linear systems. The design of the package allows new techniques to be used in existing applications without any source code changes in the applications.

10. Characteristic polynomials of linear polyacenes and their ...

Coefficients of characteristic polynomials (CP) of linear polyacenes (LP) have been shown to be obtainable from Pascal's triangle by using a graph factorisation and squaring technique. Strong subspectrality existing among the members of the linear polyacene series has been shown from the derivation of the CP's. Thus it ...

11. Enriching an effect calculus with linear types

Egger, Jeff; Møgelberg, Rasmus Ejlers; Simpson, Alex

2009-01-01

We define an enriched effect calculus'' by conservatively extending  a type theory for computational effects with primitives from linear logic. By doing so, we obtain a generalisation of linear type theory, intended as a formalism for expressing linear aspects of effects. As a worked example, we...... formulate  linearly-used continuations in the enriched effect calculus. These are captured by a fundamental translation of the enriched effect calculus into itself, which extends existing call-by-value and call-by-name linearly-used CPS translations. We show that our translation is involutive. Full...... completeness results for the various linearly-used CPS translations  follow. Our main results, the conservativity of enriching the effect calculus with linear primitives, and the involution property of the fundamental translation, are proved using a category-theoretic semantics for the enriched effect calculus...

12. Relationship between energy intake and chewing index of diets fed to pregnant ewes

Nielsen, Mette Vestergaard; Nadeau, E.; Markussen, Bo

2015-01-01

The objective was to determine whether a linear relationship exists between the metabolizable energy (ME) intake of pregnant ewes and a dietary chewing index (CI). The relationship was studied using five feeding trials with intake data from 108 pregnant ewes, 4 to 1 weeks before lambing, giving...... includes random variation of week within experiment on the intercept and linear fixed effect of week before lambing on parameter k. The maximum daily chewing time, CTmax, for the pregnant ewes was predicted to be 1/(4 × k). The MEI declined linearly with increasing dietary CI (P

13. A linear programming manual

Tuey, R. C.

1972-01-01

Computer solutions of linear programming problems are outlined. Information covers vector spaces, convex sets, and matrix algebra elements for solving simultaneous linear equations. Dual problems, reduced cost analysis, ranges, and error analysis are illustrated.

14. Linear induction accelerators

Briggs, R.J.

1986-06-01

The development of linear induction accelerators has been motivated by applications requiring high-pulsed currents of charged particles at voltages exceeding the capability of single-stage, diode-type accelerators and at currents too high for rf accelerators. In principle, one can accelerate charged particles to arbitrarily high voltages using a multi-stage induction machine, but the 50-MeV, 10-kA Advanced Test Accelerator (ATA) at LLNL is the highest voltage machine in existence at this time. The advent of magnetic pulse power systems makes sustained operation at high-repetition rates practical, and this capability for high-average power is very likely to open up many new applications of induction machines in the future. This paper surveys the US induction linac technology with primary emphasis on electron machines. A simplified description of how induction machines couple energy to the electron beam is given, to illustrate many of the general issues that bound the design space of induction linacs

15. Linear shaped charge

Peterson, David; Stofleth, Jerome H.; Saul, Venner W.

2017-07-11

Linear shaped charges are described herein. In a general embodiment, the linear shaped charge has an explosive with an elongated arrowhead-shaped profile. The linear shaped charge also has and an elongated v-shaped liner that is inset into a recess of the explosive. Another linear shaped charge includes an explosive that is shaped as a star-shaped prism. Liners are inset into crevices of the explosive, where the explosive acts as a tamper.

16. Classifying Linear Canonical Relations

Lorand, Jonathan

2015-01-01

In this Master's thesis, we consider the problem of classifying, up to conjugation by linear symplectomorphisms, linear canonical relations (lagrangian correspondences) from a finite-dimensional symplectic vector space to itself. We give an elementary introduction to the theory of linear canonical relations and present partial results toward the classification problem. This exposition should be accessible to undergraduate students with a basic familiarity with linear algebra.

17. COMPARISON OF LINEAR CONTROLLERS FOR A

Andersen, Torben Ole; Hansen, Michael Rygaard; Pedersen, Henrik C.

2005-01-01

on comparing different linear controllers, based on both simulation and experimental results, to determine what is obtainable when applying standard linear controllers to a hydraulic SISO servo system. The paper furthermore addresses how the performance may be improved by using internal pressure control......In many hydraulic control applications, classic linear controllers are still employed, although there exist a number of number of nonlinear control methods, which may be better suited for handling the intrensic non-linearities often found in hydraulic systems. The focus of this paper is therefore...... and model based information to include feedforward information. The control strategies considered are all based on measurement of piston position and pressure only....

18. Linear-Algebra Programs

Lawson, C. L.; Krogh, F. T.; Gold, S. S.; Kincaid, D. R.; Sullivan, J.; Williams, E.; Hanson, R. J.; Haskell, K.; Dongarra, J.; Moler, C. B.

1982-01-01

The Basic Linear Algebra Subprograms (BLAS) library is a collection of 38 FORTRAN-callable routines for performing basic operations of numerical linear algebra. BLAS library is portable and efficient source of basic operations for designers of programs involving linear algebriac computations. BLAS library is supplied in portable FORTRAN and Assembler code versions for IBM 370, UNIVAC 1100 and CDC 6000 series computers.

19. Linear algebra and matrices topics for a second course

Shapiro, Helene

2015-01-01

Linear algebra and matrix theory are fundamental tools for almost every area of mathematics, both pure and applied. This book combines coverage of core topics with an introduction to some areas in which linear algebra plays a key role, for example, block designs, directed graphs, error correcting codes, and linear dynamical systems. Notable features include a discussion of the Weyr characteristic and Weyr canonical forms, and their relationship to the better-known Jordan canonical form; the use of block cyclic matrices and directed graphs to prove Frobenius's theorem on the structure of the eigenvalues of a nonnegative, irreducible matrix; and the inclusion of such combinatorial topics as BIBDs, Hadamard matrices, and strongly regular graphs. Also included are McCoy's theorem about matrices with property P, the Bruck-Ryser-Chowla theorem on the existence of block designs, and an introduction to Markov chains. This book is intended for those who are familiar with the linear algebra covered in a typical first c...

20. DOES ABSOLUTE SYNONYMY EXIST IN OWERE-IGBO?

USER

The researcher also interviewed native speakers of the dialect. The study ... The word 'synonymy' means sameness of meaning, i.e., a relationship in which more ... whether absolute synonymy exists in Owere–Igbo or not. ..... 'close this book'.

1. Evolution Is Linear: Debunking Life's Little Joke.

Jenner, Ronald A

2018-01-01

Linear depictions of the evolutionary process are ubiquitous in popular culture, but linear evolutionary imagery is strongly rejected by scientists who argue that evolution branches. This point is frequently illustrated by saying that we didn't evolve from monkeys, but that we are related to them as collateral relatives. Yet, we did evolve from monkeys, but our monkey ancestors are extinct, not extant. Influential voices, such as the late Stephen Jay Gould, have misled audiences for decades by falsely portraying the linear and branching aspects of evolution to be in conflict, and by failing to distinguish between the legitimate linearity of evolutionary descent, and the branching relationships among collateral relatives that result when lineages of ancestors diverge. The purpose of this article is to correct the widespread misplaced rejection of linear evolutionary imagery, and to re-emphasize the basic truth that the evolutionary process is fundamentally linear. © 2017 WILEY Periodicals, Inc.

2. Existing Steel Railway Bridges Evaluation

Vičan, Josef; Gocál, Jozef; Odrobiňák, Jaroslav; Koteš, Peter

2016-12-01

The article describes general principles and basis of evaluation of existing railway bridges based on the concept of load-carrying capacity determination. Compared to the design of a new bridge, the modified reliability level for existing bridges evaluation should be considered due to implementation of the additional data related to bridge condition and behaviour obtained from regular inspections. Based on those data respecting the bridge remaining lifetime, a modification of partial safety factors for actions and materials could be respected in the bridge evaluation process. A great attention is also paid to the specific problems of determination of load-caring capacity of steel railway bridges in service. Recommendation for global analysis and methodology for existing steel bridge superstructure load-carrying capacity determination are described too.

3. Existing Steel Railway Bridges Evaluation

Vičan Josef

2016-12-01

Full Text Available The article describes general principles and basis of evaluation of existing railway bridges based on the concept of load-carrying capacity determination. Compared to the design of a new bridge, the modified reliability level for existing bridges evaluation should be considered due to implementation of the additional data related to bridge condition and behaviour obtained from regular inspections. Based on those data respecting the bridge remaining lifetime, a modification of partial safety factors for actions and materials could be respected in the bridge evaluation process. A great attention is also paid to the specific problems of determination of load-caring capacity of steel railway bridges in service. Recommendation for global analysis and methodology for existing steel bridge superstructure load-carrying capacity determination are described too.

4. JET VELOCITY OF LINEAR SHAPED CHARGES

Vječislav Bohanek

2012-12-01

Full Text Available Shaped explosive charges with one dimension significantly larger than the other are called linear shaped charges. Linear shaped charges are used in various industries and are applied within specific technologies for metal cutting, such as demolition of steel structures, separating spent rocket fuel tanks, demining, cutting holes in the barriers for fire service, etc. According to existing theories and models efficiency of linear shaped charges depends on the kinetic energy of the jet which is proportional to square of jet velocity. The original method for measuring velocity of linear shaped charge jet is applied in the aforementioned research. Measurements were carried out for two different linear materials, and the results are graphically presented, analysed and compared. Measurement results show a discrepancy in the measured velocity of the jet for different materials with the same ratio between linear and explosive mass (M/C per unit of surface, which is not described by presented models (the paper is published in Croatian.

5. Permafrost Hazards and Linear Infrastructure

Stanilovskaya, Julia; Sergeev, Dmitry

2014-05-01

The international experience of linear infrastructure planning, construction and exploitation in permafrost zone is being directly tied to the permafrost hazard assessment. That procedure should also consider the factors of climate impact and infrastructure protection. The current global climate change hotspots are currently polar and mountain areas. Temperature rise, precipitation and land ice conditions change, early springs occur more often. The big linear infrastructure objects cross the territories with different permafrost conditions which are sensitive to the changes in air temperature, hydrology, and snow accumulation which are connected to climatic dynamics. One of the most extensive linear structures built on permafrost worldwide are Trans Alaskan Pipeline (USA), Alaska Highway (Canada), Qinghai-Xizang Railway (China) and Eastern Siberia - Pacific Ocean Oil Pipeline (Russia). Those are currently being influenced by the regional climate change and permafrost impact which may act differently from place to place. Thermokarst is deemed to be the most dangerous process for linear engineering structures. Its formation and development depend on the linear structure type: road or pipeline, elevated or buried one. Zonal climate and geocryological conditions are also of the determining importance here. All the projects are of the different age and some of them were implemented under different climatic conditions. The effects of permafrost thawing have been recorded every year since then. The exploration and transportation companies from different countries maintain the linear infrastructure from permafrost degradation in different ways. The highways in Alaska are in a good condition due to governmental expenses on annual reconstructions. The Chara-China Railroad in Russia is under non-standard condition due to intensive permafrost response. Standards for engineering and construction should be reviewed and updated to account for permafrost hazards caused by the

6. Non linear system become linear system

Petre Bucur

2007-01-01

Full Text Available The present paper refers to the theory and the practice of the systems regarding non-linear systems and their applications. We aimed the integration of these systems to elaborate their response as well as to highlight some outstanding features.

7. Linear motor coil assembly and linear motor

2009-01-01

An ironless linear motor (5) comprising a magnet track (53) and a coil assembly (50) operating in cooperation with said magnet track (53) and having a plurality of concentrated multi-turn coils (31 a-f, 41 a-d, 51 a-k), wherein the end windings (31E) of the coils (31 a-f, 41 a-e) are substantially

8. MIDAS: Regionally linear multivariate discriminative statistical mapping.

Varol, Erdem; Sotiras, Aristeidis; Davatzikos, Christos

2018-07-01

Statistical parametric maps formed via voxel-wise mass-univariate tests, such as the general linear model, are commonly used to test hypotheses about regionally specific effects in neuroimaging cross-sectional studies where each subject is represented by a single image. Despite being informative, these techniques remain limited as they ignore multivariate relationships in the data. Most importantly, the commonly employed local Gaussian smoothing, which is important for accounting for registration errors and making the data follow Gaussian distributions, is usually chosen in an ad hoc fashion. Thus, it is often suboptimal for the task of detecting group differences and correlations with non-imaging variables. Information mapping techniques, such as searchlight, which use pattern classifiers to exploit multivariate information and obtain more powerful statistical maps, have become increasingly popular in recent years. However, existing methods may lead to important interpretation errors in practice (i.e., misidentifying a cluster as informative, or failing to detect truly informative voxels), while often being computationally expensive. To address these issues, we introduce a novel efficient multivariate statistical framework for cross-sectional studies, termed MIDAS, seeking highly sensitive and specific voxel-wise brain maps, while leveraging the power of regional discriminant analysis. In MIDAS, locally linear discriminative learning is applied to estimate the pattern that best discriminates between two groups, or predicts a variable of interest. This pattern is equivalent to local filtering by an optimal kernel whose coefficients are the weights of the linear discriminant. By composing information from all neighborhoods that contain a given voxel, MIDAS produces a statistic that collectively reflects the contribution of the voxel to the regional classifiers as well as the discriminative power of the classifiers. Critically, MIDAS efficiently assesses the

9. Limitations of existing web services

First page Back Continue Last page Overview Graphics. Limitations of existing web services. Uploading or downloading large data. Serving too many user from single source. Difficult to provide computer intensive job. Depend on internet and its bandwidth. Security of data in transition. Maintain confidentiality of data ...

10. Performance of Existing Hydrogen Stations

Sprik, Samuel [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kurtz, Jennifer M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ainscough, Christopher D [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Saur, Genevieve [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Peters, Michael C [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

2017-12-01

In this presentation, the National Renewable Energy Laboratory presented aggregated analysis results on the performance of existing hydrogen stations, including performance, operation, utilization, maintenance, safety, hydrogen quality, and cost. The U.S. Department of Energy funds technology validation work at NREL through its National Fuel Cell Technology Evaluation Center (NFCTEC).

11. Exponential increase in postprandial blood-glucose exposure with increasing carbohydrate loads using a linear carbohydrate-to-insulin ratio.

Marran, K J; Davey, B; Lang, A; Segal, D G

2013-04-10

Postprandial glucose excursions contribute significantly to average blood glucose, glycaemic variability and cardiovascular risk. Carbohydrate counting is a method of insulin dosing that balances carbohydrate load to insulin dose using a fixed ratio. Many patients and current insulin pumps calculate insulin delivery for meals based on a linear carbohydrate-to-insulin relationship. It is our hypothesis that a non-linear relationship exists between the amounts of carbohydrate consumed and the insulin required to cover it. To document blood glucose exposure in response to increasing carbohydrate loads on fixed carbohydrate-to-insulin ratios. Five type 1 diabetic subjects receiving insulin pump therapy with good control were recruited. Morning basal rates and carbohydrate- to-insulin ratios were optimised. A Medtronic glucose sensor was used for 5 days to collect data for area-under-the-curve (AUC) analysis, during which standardised meals of increasing carbohydrate loads were consumed. Increasing carbohydrate loads using a fixed carbohydrate-to-insulin ratio resulted in increasing glucose AUC. The relationship was found to be exponential rather than linear. Late postprandial hypoglycaemia followed carbohydrate loads of >60 g and this was often followed by rebound hyperglycaemia that lasted >6 hours. A non-linear relationship exists between carbohydrates consumed and the insulin required to cover them. This has implications for control of postprandial blood sugars, especially when consuming large carbohydrate loads. Further studies are required to look at the optimal ratios, duration and type of insulin boluses required to cover increasing carbohydrate loads.

12. Linear collider: a preview

Wiedemann, H.

1981-11-01

Since no linear colliders have been built yet it is difficult to know at what energy the linear cost scaling of linear colliders drops below the quadratic scaling of storage rings. There is, however, no doubt that a linear collider facility for a center of mass energy above say 500 GeV is significantly cheaper than an equivalent storage ring. In order to make the linear collider principle feasible at very high energies a number of problems have to be solved. There are two kinds of problems: one which is related to the feasibility of the principle and the other kind of problems is associated with minimizing the cost of constructing and operating such a facility. This lecture series describes the problems and possible solutions. Since the real test of a principle requires the construction of a prototype I will in the last chapter describe the SLC project at the Stanford Linear Accelerator Center.

13. Basic linear algebra

Blyth, T S

2002-01-01

Basic Linear Algebra is a text for first year students leading from concrete examples to abstract theorems, via tutorial-type exercises. More exercises (of the kind a student may expect in examination papers) are grouped at the end of each section. The book covers the most important basics of any first course on linear algebra, explaining the algebra of matrices with applications to analytic geometry, systems of linear equations, difference equations and complex numbers. Linear equations are treated via Hermite normal forms which provides a successful and concrete explanation of the notion of linear independence. Another important highlight is the connection between linear mappings and matrices leading to the change of basis theorem which opens the door to the notion of similarity. This new and revised edition features additional exercises and coverage of Cramer's rule (omitted from the first edition). However, it is the new, extra chapter on computer assistance that will be of particular interest to readers:...

14. Linear collider: a preview

Wiedemann, H.

1981-11-01

Since no linear colliders have been built yet it is difficult to know at what energy the linear cost scaling of linear colliders drops below the quadratic scaling of storage rings. There is, however, no doubt that a linear collider facility for a center of mass energy above say 500 GeV is significantly cheaper than an equivalent storage ring. In order to make the linear collider principle feasible at very high energies a number of problems have to be solved. There are two kinds of problems: one which is related to the feasibility of the principle and the other kind of problems is associated with minimizing the cost of constructing and operating such a facility. This lecture series describes the problems and possible solutions. Since the real test of a principle requires the construction of a prototype I will in the last chapter describe the SLC project at the Stanford Linear Accelerator Center

15. Matrices and linear transformations

Cullen, Charles G

1990-01-01

""Comprehensive . . . an excellent introduction to the subject."" - Electronic Engineer's Design Magazine.This introductory textbook, aimed at sophomore- and junior-level undergraduates in mathematics, engineering, and the physical sciences, offers a smooth, in-depth treatment of linear algebra and matrix theory. The major objects of study are matrices over an arbitrary field. Contents include Matrices and Linear Systems; Vector Spaces; Determinants; Linear Transformations; Similarity: Part I and Part II; Polynomials and Polynomial Matrices; Matrix Analysis; and Numerical Methods. The first

16. Efficient Non Linear Loudspeakers

Petersen, Bo R.; Agerkvist, Finn T.

2006-01-01

Loudspeakers have traditionally been designed to be as linear as possible. However, as techniques for compensating non linearities are emerging, it becomes possible to use other design criteria. This paper present and examines a new idea for improving the efficiency of loudspeakers at high levels...... by changing the voice coil layout. This deliberate non-linear design has the benefit that a smaller amplifier can be used, which has the benefit of reducing system cost as well as reducing power consumption....

17. Multivariate covariance generalized linear models

Bonat, W. H.; Jørgensen, Bent

2016-01-01

are fitted by using an efficient Newton scoring algorithm based on quasi-likelihood and Pearson estimating functions, using only second-moment assumptions. This provides a unified approach to a wide variety of types of response variables and covariance structures, including multivariate extensions......We propose a general framework for non-normal multivariate data analysis called multivariate covariance generalized linear models, designed to handle multivariate response variables, along with a wide range of temporal and spatial correlation structures defined in terms of a covariance link...... function combined with a matrix linear predictor involving known matrices. The method is motivated by three data examples that are not easily handled by existing methods. The first example concerns multivariate count data, the second involves response variables of mixed types, combined with repeated...

18. Linear accelerator for radioisotope production

Hansborough, L.D.; Hamm, R.W.; Stovall, J.E.

1982-02-01

A 200- to 500-μA source of 70- to 90-MeV protons would be a valuable asset to the nuclear medicine program. A linear accelerator (linac) can achieve this performance, and it can be extended to even higher energies and currents. Variable energy and current options are available. A 70-MeV linac is described, based on recent innovations in linear accelerator technology; it would be 27.3 m long and cost approx. 6 million. By operating the radio-frequency (rf) power system at a level necessary to produce a 500-μA beam current, the cost of power deposited in the radioisotope-production target is comparable with existing cyclotrons. If the rf-power system is operated at full power, the same accelerator is capable of producing an 1140-μA beam, and the cost per beam watt on the target is less than half that of comparable cyclotrons 19. Linear integrated circuits Carr, Joseph 1996-01-01 The linear IC market is large and growing, as is the demand for well trained technicians and engineers who understand how these devices work and how to apply them. Linear Integrated Circuits provides in-depth coverage of the devices and their operation, but not at the expense of practical applications in which linear devices figure prominently. This book is written for a wide readership from FE and first degree students, to hobbyists and professionals.Chapter 1 offers a general introduction that will provide students with the foundations of linear IC technology. From chapter 2 onwa 20. Fault tolerant linear actuator Tesar, Delbert 2004-09-14 In varying embodiments, the fault tolerant linear actuator of the present invention is a new and improved linear actuator with fault tolerance and positional control that may incorporate velocity summing, force summing, or a combination of the two. In one embodiment, the invention offers a velocity summing arrangement with a differential gear between two prime movers driving a cage, which then drives a linear spindle screw transmission. Other embodiments feature two prime movers driving separate linear spindle screw transmissions, one internal and one external, in a totally concentric and compact integrated module. 1. Superconducting linear accelerator cryostat Ben-Zvi, I.; Elkonin, B.V.; Sokolowski, J.S. 1984-01-01 A large vertical cryostat for a superconducting linear accelerator using quarter wave resonators has been developed. The essential technical details, operational experience and performance are described. (author) 2. The EXIST Mission Concept Study Fishman, Gerald J.; Grindlay, J.; Hong, J. 2008-01-01 EXIST is a mission designed to find and study black holes (BHs) over a wide range of environments and masses, including: 1) BHs accreting from binary companions or dense molecular clouds throughout our Galaxy and the Local Group, 2) supermassive black holes (SMBHs) lying dormant in galaxies that reveal their existence by disrupting passing stars, and 3) SMBHs that are hidden from our view at lower energies due to obscuration by the gas that they accrete. 4) the birth of stellar mass BHs which is accompanied by long cosmic gamma-ray bursts (GRBs) which are seen several times a day and may be associated with the earliest stars to form in the Universe. EXIST will provide an order of magnitude increase in sensitivity and angular resolution as well as greater spectral resolution and bandwidth compared with earlier hard X-ray survey telescopes. With an onboard optical-infra red (IR) telescope, EXIST will measure the spectra and redshifts of GRBs and their utility as cosmological probes of the highest z universe and epoch of reionization. The mission would retain its primary goal of being the Black Hole Finder Probe in the Beyond Einstein Program. However, the new design for EXIST proposed to be studied here represents a significant advance from its previous incarnation as presented to BEPAC. The mission is now less than half the total mass, would be launched on the smallest EELV available (Atlas V-401) for a Medium Class mission, and most importantly includes a two-telescope complement that is ideally suited for the study of both obscured and very distant BHs. EXIST retains its very wide field hard X-ray imaging High Energy Telescope (HET) as the primary instrument, now with improved angular and spectral resolution, and in a more compact payload that allows occasional rapid slews for immediate optical/IR imaging and spectra of GRBs and AGN as well as enhanced hard X-ray spectra and timing with pointed observations. The mission would conduct a 2 year full sky survey in 3. Europe - space for transcultural existence? Tamcke, Martin; Janny, de Jong; Klein, Lars; Waal, Margriet 2013-01-01 Europe - Space for Transcultural Existence? is the first volume of the new series, Studies in Euroculture, published by Göttingen University Press. The series derives its name from the Erasmus Mundus Master of Excellence Euroculture: Europe in the Wider World, a two year programme offered by a consortium of eight European universities in collaboration with four partner universities outside Europe. This master highlights regional, national and supranational dimensions of the European democrati... 4. Existence of undiscovered Uranian satellites Boice, D.C. 1986-04-01 Structure in the Uranian ring system as observed in recent occultations may contain indirect evidence for the existence of undiscovered satellites. Using the Alfven and Arrhenius (1975, 1976) scenario for the formation of planetary systems, the orbital radii of up to nine hypothetical satellites interior to Miranda are computed. These calculations should provide interesting comparisons when the results from the Voyager 2 encounter with Uranus are made public. 15 refs., 1 fig., 1 tab 5. UNCITRAL: Changes to existing law Andersson, Joakim 2008-01-01 The UNCITRAL Convention on Contracts for the International Carriage of Goods [wholly or partly] by Sea has an ambition of replacing current maritime regimes and expands the application of the Convention to include also multimodal transport. This thesis questions what changes to existing law, in certain areas, the new Convention will bring compared to the current regimes. In the initial part, the thesis provides for a brief background and history of international maritime regulations and focus... 6. Existence Results for Incompressible Magnetoelasticity Kružík, Martin; Stefanelli, U.; Zeman, J. 2015-01-01 Roč. 35, č. 6 (2015), s. 2615-2623 ISSN 1078-0947 R&D Projects: GA ČR GA13-18652S Institutional support: RVO:67985556 Keywords : magnetoelasticity * magnetostrictive solids * incompressibility * existence of minimizers * quasistatic evolution * energetic solution Subject RIV: BA - General Mathematics Impact factor: 1.127, year: 2015 http://library.utia.cas.cz/separaty/2015/MTR/kruzik-0443017.pdf 7. Linear causal modeling with structural equations Mulaik, Stanley A 2009-01-01 Emphasizing causation as a functional relationship between variables that describe objects, Linear Causal Modeling with Structural Equations integrates a general philosophical theory of causation with structural equation modeling (SEM) that concerns the special case of linear causal relations. In addition to describing how the functional relation concept may be generalized to treat probabilistic causation, the book reviews historical treatments of causation and explores recent developments in experimental psychology on studies of the perception of causation. It looks at how to perceive causal 8. Linear colliders - prospects 1985 Rees, J. 1985-06-01 We discuss the scaling laws of linear colliders and their consequences for accelerator design. We then report on the SLAC Linear Collider project and comment on experience gained on that project and its application to future colliders. 9 refs., 2 figs 9. The SLAC linear collider Richter, B. 1985-01-01 A report is given on the goals and progress of the SLAC Linear Collider. The author discusses the status of the machine and the detectors and give an overview of the physics which can be done at this new facility. He also gives some ideas on how (and why) large linear colliders of the future should be built 10. Linear Programming (LP) Rogner, H.H. 1989-01-01 The submitted sections on linear programming are extracted from 'Theorie und Technik der Planung' (1978) by W. Blaas and P. Henseler and reformulated for presentation at the Workshop. They consider a brief introduction to the theory of linear programming and to some essential aspects of the SIMPLEX solution algorithm for the purposes of economic planning processes. 1 fig 11. Racetrack linear accelerators Rowe, C.H.; Wilton, M.S. de. 1979-01-01 An improved recirculating electron beam linear accelerator of the racetrack type is described. The system comprises a beam path of four straight legs with four Pretzel bending magnets at the end of each leg to direct the beam into the next leg of the beam path. At least one of the beam path legs includes a linear accelerator. (UK) 12. Single Particle Linear and Nonlinear Dynamics Cai, Y 2004-06-25 I will give a comprehensive review of existing particle tracking tools to assess long-term particle stability for small and large accelerators in the presence of realistic magnetic imperfections and machine misalignments. The emphasis will be on the tracking and analysis tools based upon the differential algebra, Lie operator, and ''polymorphism''. Using these tools, a uniform linear and non-linear analysis will be outlined as an application of the normal form. 13. Single Particle Linear and Nonlinear Dynamics Cai, Y 2004-01-01 I will give a comprehensive review of existing particle tracking tools to assess long-term particle stability for small and large accelerators in the presence of realistic magnetic imperfections and machine misalignments. The emphasis will be on the tracking and analysis tools based upon the differential algebra, Lie operator, and ''polymorphism''. Using these tools, a uniform linear and non-linear analysis will be outlined as an application of the normal form 14. Semidefinite linear complementarity problems Eckhardt, U. 1978-04-01 Semidefinite linear complementarity problems arise by discretization of variational inequalities describing e.g. elastic contact problems, free boundary value problems etc. In the present paper linear complementarity problems are introduced and the theory as well as the numerical treatment of them are described. In the special case of semidefinite linear complementarity problems a numerical method is presented which combines the advantages of elimination and iteration methods without suffering from their drawbacks. This new method has very attractive properties since it has a high degree of invariance with respect to the representation of the set of all feasible solutions of a linear complementarity problem by linear inequalities. By means of some practical applications the properties of the new method are demonstrated. (orig.) [de 15. Linear algebra done right Axler, Sheldon 2015-01-01 This best-selling textbook for a second course in linear algebra is aimed at undergrad math majors and graduate students. The novel approach taken here banishes determinants to the end of the book. The text focuses on the central goal of linear algebra: understanding the structure of linear operators on finite-dimensional vector spaces. The author has taken unusual care to motivate concepts and to simplify proofs. A variety of interesting exercises in each chapter helps students understand and manipulate the objects of linear algebra. The third edition contains major improvements and revisions throughout the book. More than 300 new exercises have been added since the previous edition. Many new examples have been added to illustrate the key ideas of linear algebra. New topics covered in the book include product spaces, quotient spaces, and dual spaces. Beautiful new formatting creates pages with an unusually pleasant appearance in both print and electronic versions. No prerequisites are assumed other than the ... 16. An H-module linear actuator for medical equipment applications Liu, Xiao; Wu, Keyuan; ye, yunyue 2012-01-01 An H-module linear actuator (HMLA) is proposed in this paper for medical equipment applications. Compared to the existing linear actuators used in medical equipment, the proposed H-module linear actuator has much lower normal force, which makes use of an additional air-suspension system unnecessary... 17. Handbook on linear motor application 1988-10-01 This book guides the application for Linear motor. It lists classification and speciality of Linear Motor, terms of linear-induction motor, principle of the Motor, types on one-side linear-induction motor, bilateral linear-induction motor, linear-DC Motor on basic of the motor, linear-DC Motor for moving-coil type, linear-DC motor for permanent-magnet moving type, linear-DC motor for electricity non-utility type, linear-pulse motor for variable motor, linear-pulse motor for permanent magneto type, linear-vibration actuator, linear-vibration actuator for moving-coil type, linear synchronous motor, linear electromagnetic motor, linear electromagnetic solenoid, technical organization and magnetic levitation and linear motor and sensor. 18. Quantum logics with existence property Schindler, C. 1991-01-01 A quantum logic (σ-orthocomplete orthomodular poset L with a convex, unital, and separating set Δ of states) is said to have the existence property if the expectation functionals on lin(Δ) associated with the bounded observables of L form a vector space. Classical quantum logics as well as the Hilbert space logics of traditional quantum mechanics have this property. The author shows that, if a quantum logic satisfies certain conditions in addition to having property E, then the number of its blocks (maximal classical subsystems) must either be one (classical logics) or uncountable (as in Hilbert space logics) 19. Minimal solution of general dual fuzzy linear systems Abbasbandy, S.; Otadi, M.; Mosleh, M. 2008-01-01 Fuzzy linear systems of equations, play a major role in several applications in various area such as engineering, physics and economics. In this paper, we investigate the existence of a minimal solution of general dual fuzzy linear equation systems. Two necessary and sufficient conditions for the minimal solution existence are given. Also, some examples in engineering and economic are considered 20. Linear measure functional differential equations with infinite delay Monteiro, G. (Giselle Antunes); Slavík, A. 2014-01-01 We use the theory of generalized linear ordinary differential equations in Banach spaces to study linear measure functional differential equations with infinite delay. We obtain new results concerning the existence, uniqueness, and continuous dependence of solutions. Even for equations with a finite delay, our results are stronger than the existing ones. Finally, we present an application to functional differential equations with impulses. 1. Existence and Policy Effectiveness in Feedback Nash LQ-Games Nicola Acocella 2008-12-01 Full Text Available This paper illustrates how the classical theory of economic policy can profitably be used to verify some properties of the Linear Nash Feedback Equilibrium in difference LQ-games. In particular, we find that both a necessary condition for the equilibrium existence and a sufficient condition for policy ineffectiveness can be defined in the terms of the simple Tinbergen counting rule. 2. The existence of solutions of q-difference-differential equations. Wang, Xin-Li; Wang, Hua; Xu, Hong-Yan 2016-01-01 By using the Nevanlinna theory of value distribution, we investigate the existence of solutions of some types of non-linear q-difference differential equations. In particular, we generalize the Rellich-Wittich-type theorem and Malmquist-type theorem about differential equations to the case of q-difference differential equations (system). 3. Ultra-Low-Dropout Linear Regulator Thornton, Trevor; Lepkowski, William; Wilk, Seth 2011-01-01 A radiation-tolerant, ultra-low-dropout linear regulator can operate between -150 and 150 C. Prototype components were demonstrated to be performing well after a total ionizing dose of 1 Mrad (Si). Unlike existing components, the linear regulator developed during this activity is unconditionally stable over all operating regimes without the need for an external compensation capacitor. The absence of an external capacitor reduces overall system mass/volume, increases reliability, and lowers cost. Linear regulators generate a precisely controlled voltage for electronic circuits regardless of fluctuations in the load current that the circuit draws from the regulator. 4. Linear ubiquitination in immunity. Shimizu, Yutaka; Taraborrelli, Lucia; Walczak, Henning 2015-07-01 Linear ubiquitination is a post-translational protein modification recently discovered to be crucial for innate and adaptive immune signaling. The function of linear ubiquitin chains is regulated at multiple levels: generation, recognition, and removal. These chains are generated by the linear ubiquitin chain assembly complex (LUBAC), the only known ubiquitin E3 capable of forming the linear ubiquitin linkage de novo. LUBAC is not only relevant for activation of nuclear factor-κB (NF-κB) and mitogen-activated protein kinases (MAPKs) in various signaling pathways, but importantly, it also regulates cell death downstream of immune receptors capable of inducing this response. Recognition of the linear ubiquitin linkage is specifically mediated by certain ubiquitin receptors, which is crucial for translation into the intended signaling outputs. LUBAC deficiency results in attenuated gene activation and increased cell death, causing pathologic conditions in both, mice, and humans. Removal of ubiquitin chains is mediated by deubiquitinases (DUBs). Two of them, OTULIN and CYLD, are constitutively associated with LUBAC. Here, we review the current knowledge on linear ubiquitination in immune signaling pathways and the biochemical mechanisms as to how linear polyubiquitin exerts its functions distinctly from those of other ubiquitin linkage types. © 2015 The Authors. Immunological Reviews Published by John Wiley & Sons Ltd. 5. Robust linear discriminant analysis with distance based estimators Lim, Yai-Fung; Yahaya, Sharipah Soaad Syed; Ali, Hazlina 2017-11-01 Linear discriminant analysis (LDA) is one of the supervised classification techniques concerning relationship between a categorical variable and a set of continuous variables. The main objective of LDA is to create a function to distinguish between populations and allocating future observations to previously defined populations. Under the assumptions of normality and homoscedasticity, the LDA yields optimal linear discriminant rule (LDR) between two or more groups. However, the optimality of LDA highly relies on the sample mean and pooled sample covariance matrix which are known to be sensitive to outliers. To alleviate these conflicts, a new robust LDA using distance based estimators known as minimum variance vector (MVV) has been proposed in this study. The MVV estimators were used to substitute the classical sample mean and classical sample covariance to form a robust linear discriminant rule (RLDR). Simulation and real data study were conducted to examine on the performance of the proposed RLDR measured in terms of misclassification error rates. The computational result showed that the proposed RLDR is better than the classical LDR and was comparable with the existing robust LDR. 6. Matrices and linear algebra Schneider, Hans 1989-01-01 Linear algebra is one of the central disciplines in mathematics. A student of pure mathematics must know linear algebra if he is to continue with modern algebra or functional analysis. Much of the mathematics now taught to engineers and physicists requires it.This well-known and highly regarded text makes the subject accessible to undergraduates with little mathematical experience. Written mainly for students in physics, engineering, economics, and other fields outside mathematics, the book gives the theory of matrices and applications to systems of linear equations, as well as many related t 7. Linearity in Process Languages Nygaard, Mikkel; Winskel, Glynn 2002-01-01 The meaning and mathematical consequences of linearity (managing without a presumed ability to copy) are studied for a path-based model of processes which is also a model of affine-linear logic. This connection yields an affine-linear language for processes, automatically respecting open......-map bisimulation, in which a range of process operations can be expressed. An operational semantics is provided for the tensor fragment of the language. Different ways to make assemblies of processes lead to different choices of exponential, some of which respect bisimulation.... 8. Elements of linear space Amir-Moez, A R; Sneddon, I N 1962-01-01 Elements of Linear Space is a detailed treatment of the elements of linear spaces, including real spaces with no more than three dimensions and complex n-dimensional spaces. The geometry of conic sections and quadric surfaces is considered, along with algebraic structures, especially vector spaces and transformations. Problems drawn from various branches of geometry are given.Comprised of 12 chapters, this volume begins with an introduction to real Euclidean space, followed by a discussion on linear transformations and matrices. The addition and multiplication of transformations and matrices a 9. Applied linear regression Weisberg, Sanford 2013-01-01 Praise for the Third Edition ""...this is an excellent book which could easily be used as a course text...""-International Statistical Institute The Fourth Edition of Applied Linear Regression provides a thorough update of the basic theory and methodology of linear regression modeling. Demonstrating the practical applications of linear regression analysis techniques, the Fourth Edition uses interesting, real-world exercises and examples. Stressing central concepts such as model building, understanding parameters, assessing fit and reliability, and drawing conclusions, the new edition illus 10. Does cold nuclear fusion exist? Brudanin, V.B.; Bystritskij, V.M.; Egorov, V.G.; Shamsutdinov, S.G.; Shyshkin, A.L.; Stolupin, V.A.; Yutlandov, I.A. 1989-01-01 The results of investigation of cold nuclear fusion on palladium are given both for electrolysis of heavy water D 2 O and mixture D 2 O + H 2 O) (1:1) and for palladium saturation with gaseous deuterium. The possibility of existance of this phenomenon was examined by detection of neutrons and gamma quanta from reactions: d + d → 3 He + n + 3.27 MeV, p + d → 3 He + γ + 5.5 MeV. Besides these reactions were identified by measuring the characteristic X radiation of palladium due to effect of charged products 3 He, p, t. The upper limits of the intensities of hypothetical sources of neutrons and gamma quanta at the 95% confidence level were obtained to be Q n ≤ 2x10 -2 n/sxcm 3 Pd, Q γ ≤ 2x10 -3 γ/sxcm 3 Pd. 2 refs.; 4 figs.; 2 tabs 11. Straightening: existence, uniqueness and stability Destrade, M.; Ogden, R. W.; Sgura, I.; Vergori, L. 2014-01-01 One of the least studied universal deformations of incompressible nonlinear elasticity, namely the straightening of a sector of a circular cylinder into a rectangular block, is revisited here and, in particular, issues of existence and stability are addressed. Particular attention is paid to the system of forces required to sustain the large static deformation, including by the application of end couples. The influence of geometric parameters and constitutive models on the appearance of wrinkles on the compressed face of the block is also studied. Different numerical methods for solving the incremental stability problem are compared and it is found that the impedance matrix method, based on the resolution of a matrix Riccati differential equation, is the more precise. PMID:24711723 12. Why do interstellar grains exist Seab, C.G.; Hollenbach, D.J.; Mckee, C.F.; Tielens, A.G.G.M. 1986-01-01 There exists a discrepancy between calculated destruction rates of grains in the interstellar medium and postulated sources of new grains. This problem was examined by modelling the global life cycle of grains in the galaxy. The model includes: grain destruction due to supernovae shock waves; grain injection from cool stars, planetary nebulae, star formation, novae, and supernovae; grain growth by accretion in dark clouds; and a mixing scheme between phases of the interstellar medium. Grain growth in molecular clouds is considered as a mechanism or increasing the formation rate. To decrease the shock destruction rate, several new physical processes, such as partial vaporization effects in grain-grain collisions, breakdown of the small Larmor radius approximation for betatron acceleration, and relaxation of the steady-state shock assumption are included 13. Non-linearities in Holocene floodplain sediment storage Notebaert, Bastiaan; Nils, Broothaerts; Jean-François, Berger; Gert, Verstraeten 2013-04-01 Floodplain sediment storage is an important part of the sediment cascade model, buffering sediment delivery between hillslopes and oceans, which is hitherto not fully quantified in contrast to other global sediment budget components. Quantification and dating of floodplain sediment storage is data and financially demanding, limiting contemporary estimates for larger spatial units to simple linear extrapolations from a number of smaller catchments. In this paper we will present non-linearities in both space and time for floodplain sediment budgets in three different catchments. Holocene floodplain sediments of the Dijle catchment in the Belgian loess region, show a clear distinction between morphological stages: early Holocene peat accumulation, followed by mineral floodplain aggradation from the start of the agricultural period on. Contrary to previous assumptions, detailed dating of this morphological change at different shows an important non-linearity in geomorphologic changes of the floodplain, both between and within cross sections. A second example comes from the Pre-Alpine French Valdaine region, where non-linearities and complex system behavior exists between (temporal) patterns of soil erosion and floodplain sediment deposition. In this region Holocene floodplain deposition is characterized by different cut-and-fill phases. The quantification of these different phases shows a complicated image of increasing and decreasing floodplain sediment storage, which hampers the image of increasing sediment accumulation over time. Although fill stages may correspond with large quantities of deposited sediment and traditionally calculated sedimentation rates for such stages are high, they do not necessary correspond with a long-term net increase in floodplain deposition. A third example is based on the floodplain sediment storage in the Amblève catchment, located in the Belgian Ardennes uplands. Detailed floodplain sediment quantification for this catchments shows 14. Characterizing driver-response relationships in marine pelagic ecosystems for improved ocean management. Hunsicker, Mary E; Kappel, Carrie V; Selkoe, Kimberly A; Halpern, Benjamin S; Scarborough, Courtney; Mease, Lindley; Amrhein, Alisan 2016-04-01 Scientists and resource managers often use methods and tools that assume ecosystem components respond linearly to environmental drivers and human stressors. However, a growing body of literature demonstrates that many relationships are-non-linear, where small changes in a driver prompt a disproportionately large ecological response. We aim to provide a comprehensive assessment of the relationships between drivers and ecosystem components to identify where and when non-linearities are likely to occur. We focused our analyses on one of the best-studied marine systems, pelagic ecosystems, which allowed us to apply robust statistical techniques on a large pool of previously published studies. In this synthesis, we (1) conduct a wide literature review on single driver-response relationships in pelagic systems, (2) use statistical models to identify the degree of non-linearity in these relationships, and (3) assess whether general patterns exist in the strengths and shapes of non-linear relationships across drivers. Overall we found that non-linearities are common in pelagic ecosystems, comprising at least 52% of all driver-response relation- ships. This is likely an underestimate, as papers with higher quality data and analytical approaches reported non-linear relationships at a higher frequency (on average 11% more). Consequently, in the absence of evidence for a linear relationship, it is safer to assume a relationship is non-linear. Strong non-linearities can lead to greater ecological and socioeconomic consequences if they are unknown (and/or unanticipated), but if known they may provide clear thresholds to inform management targets. In pelagic systems, strongly non-linear relationships are often driven by climate and trophodynamic variables but are also associated with local stressors, such as overfishing and pollution, that can be more easily controlled by managers. Even when marine resource managers cannot influence ecosystem change, they can use information 15. Welfare Economics: A Story of Existence Khalid Iqbal 2017-06-01 Full Text Available The purpose of this study is to explore that, despite severe challenges, welfare economics still exists. This descriptive study is conducted through some specific time line developments in this field. Economists are divided over the veracity and survival of the welfare economics. Welfare economics emphasizes on the optimum resource and goods allocation with the objective of better living standard, materialistic gains, social welfare and ethical decisions. It origins back to the political economics and utilitarianism. Adam Smith, Irving Fisher and Pareto contributed significantly towards it. During 1930 to 1940, American and British approaches were developed. Many economists tried to explore the relationship between level of income and happiness. Amartya Sen gave the comparative approach and Tinbergen pioneered the theory of equity. Contemporarily the futuristic restoration of welfare economics is on trial and hopes are alive. This study may be useful to understand the transitional and survival process of welfare economics. 16. Linear system theory Callier, Frank M.; Desoer, Charles A. 1991-01-01 The aim of this book is to provide a systematic and rigorous access to the main topics of linear state-space system theory in both the continuous-time case and the discrete-time case; and the I/O description of linear systems. The main thrusts of the work are the analysis of system descriptions and derivations of their properties, LQ-optimal control, state feedback and state estimation, and MIMO unity-feedback systems. 17. Existe sujeito em Michel Maffesoli? Marli Appel da Silva 2010-06-01 Full Text Available Este ensaio discute a concepção de sujeito na abordagem teórica de Michel Maffesoli. As ideias desse autor estão em voga em alguns meios acadêmicos no Brasil e são difundidas por algumas mídias de grande circulação nacional. Entretanto, ao longo de suas obras, os pressupostos que definem quem é o sujeito maffesoliano se encontram pouco clarificados. Portanto, para alcançar o objetivo a que se propõe, este ensaio desenvolve uma análise da epistemologia e da ontologia maffesoliana com a finalidade de compreender as origens dos pressupostos desse autor, ou seja, as teorias e os autores em que Maffesoli se baseou para desenvolver uma visão de sujeito. Com essa compreensão, pretende-se responder à questão: existe sujeito na abordagem teórica de Maffesoli. 18. LDEF data: Comparisons with existing models Coombs, Cassandra R.; Watts, Alan J.; Wagner, John D.; Atkinson, Dale R. 1993-04-01 The relationship between the observed cratering impact damage on the Long Duration Exposure Facility (LDEF) versus the existing models for both the natural environment of micrometeoroids and the man-made debris was investigated. Experimental data was provided by several LDEF Principal Investigators, Meteoroid and Debris Special Investigation Group (M&D SIG) members, and by the Kennedy Space Center Analysis Team (KSC A-Team) members. These data were collected from various aluminum materials around the LDEF satellite. A PC (personal computer) computer program, SPENV, was written which incorporates the existing models of the Low Earth Orbit (LEO) environment. This program calculates the expected number of impacts per unit area as functions of altitude, orbital inclination, time in orbit, and direction of the spacecraft surface relative to the velocity vector, for both micrometeoroids and man-made debris. Since both particle models are couched in terms of impact fluxes versus impactor particle size, and much of the LDEF data is in the form of crater production rates, scaling laws have been used to relate the two. Also many hydrodynamic impact computer simulations were conducted, using CTH, of various impact events, that identified certain modes of response, including simple metallic target cratering, perforations and delamination effects of coatings. 19. Tried and True: Springing into Linear Models Darling, Gerald 2012-01-01 In eighth grade, students usually learn about forces in science class and linear relationships in math class, crucial topics that form the foundation for further study in science and engineering. An activity that links these two fundamental concepts involves measuring the distance a spring stretches as a function of how much weight is suspended… 20. Dual exponential polynomials and linear differential equations Wen, Zhi-Tao; Gundersen, Gary G.; Heittokangas, Janne 2018-01-01 We study linear differential equations with exponential polynomial coefficients, where exactly one coefficient is of order greater than all the others. The main result shows that a nontrivial exponential polynomial solution of such an equation has a certain dual relationship with the maximum order coefficient. Several examples illustrate our results and exhibit possibilities that can occur. 1. On the existence of perturbed Robertson-Walker universes D'Eath, P.D. 1976-01-01 Solutions of the full nonlinear field equations of general relativity near the Robertson-Walker universes are examined, together with their relation to linearized perturbations. A method due to Choquet-Bruhat and Deser is used to prove existence theorems for solutions near Robertson-Walker constraint data of the constraint equations on a spacelike hypersurface. These theorems allow one to regard the matter fluctuations as independent quantities, ranging over certain function spaces. In the k=-1 case the existence theory describes perturbations which may vary within uniform bounds throughout space. When k=+1 a modification of the method leads to a theorem which clarifies some unusual features of these constraint perturbations. The k=0 existence theorem refers only to perturbations which die away at large distances. The connection between linearized constraint solutions and solutions of the full constraints is discussed. For k= +- 1 backgrounds, solutions of the linearized constraints are analyzed using transverse-traceless decompositions of symmetric tensors. Finally the time-evolution of perturbed constraint data and the validity of linearized perturbation theory for Robertson-Walker universes are considered 2. Uso da regressão linear para estimativa da relação entre a condutividade elétrica e a composição iônica da água de irrigação Use of linear regression to estimate the relationship between electrical conductivity and ionic composition of irrigation water Giorgio M. Ribeiro 2005-03-01 Full Text Available Vários estudos vêm sendo realizados ultimamente, com o propósito de se avaliar a qualidade de água de irrigação na região semi-árida do Nordeste brasileiro. Em alguns desses estudos, os autores têm ajustado diversas características químicas, como cálcio, magnésio, sódio e cloreto e soma de cátions, em função da condutividade elétrica (CE através de equações empíricas; porém atenção deve ser dada às variações temporal e espacial dessas variáveis. Objetivou-se, com o presente trabalho, avaliar a influência da fonte, da época e do tipo de solo sobre a condutividade elétrica, em função dos íons da água de irrigação, utilizando-se a regressão linear. Foi utilizado um banco de dados composto por 562 análises, oriundas de 55 propriedades rurais. As determinações químicas feitas nas amostras de águas, foram: pH, CE, Ca2+, Mg2+, Na+, K+, Cl-, HCO3-, CO3(2- e SO4(2-. A partir de janeiro de 1988 realizaram-se amostragens nas propriedades, até 411 dias. O banco de dados foi dividido em 14 épocas de amostragem, três fontes (poço, rio e açude e para 10 solos. Para se comparar as equações ajustadas, empregou-se o teste de identidade de modelo, cujos resultados mostraram que as equações lineares ajustadas com a condutividade elétrica em função dos teores de cálcio, magnésio, potássio, sódio, cloreto, bicarbonato, carbonato e sulfato variaram significativamente com a época de amostragem, a fonte de água e com o tipo de solo.Several studies have been accomplished lately to evaluate irrigation water quality in the semi-arid region of the Northeast Brazil. In some of these studies, the authors have adjusted some chemical characteristics such as calcium, magnesium, sodium, chloride and sum of cations as a function of electrical conductivity (EC through empirical equations, however attention should be given to temporal and spatial variations. In this paper, the influence of water source, time of sampling 3. Further linear algebra Blyth, T S 2002-01-01 Most of the introductory courses on linear algebra develop the basic theory of finite­ dimensional vector spaces, and in so doing relate the notion of a linear mapping to that of a matrix. Generally speaking, such courses culminate in the diagonalisation of certain matrices and the application of this process to various situations. Such is the case, for example, in our previous SUMS volume Basic Linear Algebra. The present text is a continuation of that volume, and has the objective of introducing the reader to more advanced properties of vector spaces and linear mappings, and consequently of matrices. For readers who are not familiar with the contents of Basic Linear Algebra we provide an introductory chapter that consists of a compact summary of the prerequisites for the present volume. In order to consolidate the student's understanding we have included a large num­ ber of illustrative and worked examples, as well as many exercises that are strategi­ cally placed throughout the text. Solutions to the ex... 4. Generalized non-linear Schroedinger hierarchy Aratyn, H.; Gomes, J.F.; Zimerman, A.H. 1994-01-01 The importance in studying the completely integrable models have became evident in the last years due to the fact that those models present an algebraic structure extremely rich, providing the natural scenery for solitons description. Those models can be described through non-linear differential equations, pseudo-linear operators (Lax formulation), or a matrix formulation. The integrability implies in the existence of a conservation law associated to each of degree of freedom. Each conserved charge Q i can be associated to a Hamiltonian, defining a time evolution related to to a time t i through the Hamilton equation ∂A/∂t i =[A,Q i ]. Particularly, for a two-dimensions field theory, infinite degree of freedom exist, and consequently infinite conservation laws describing the time evolution in space of infinite times. The Hamilton equation defines a hierarchy of models which present a infinite set of conservation laws. This paper studies the generalized non-linear Schroedinger hierarchy 5. Summary of existing uncertainty methods Glaeser, Horst 2013-01-01 A summary of existing and most used uncertainty methods is presented, and the main features are compared. One of these methods is the order statistics method based on Wilks' formula. It is applied in safety research as well as in licensing. This method has been first proposed by GRS for use in deterministic safety analysis, and is now used by many organisations world-wide. Its advantage is that the number of potential uncertain input and output parameters is not limited to a small number. Such a limitation was necessary for the first demonstration of the Code Scaling Applicability Uncertainty Method (CSAU) by the United States Regulatory Commission (USNRC). They did not apply Wilks' formula in their statistical method propagating input uncertainties to obtain the uncertainty of a single output variable, like peak cladding temperature. A Phenomena Identification and Ranking Table (PIRT) was set up in order to limit the number of uncertain input parameters, and consequently, the number of calculations to be performed. Another purpose of such a PIRT process is to identify the most important physical phenomena which a computer code should be suitable to calculate. The validation of the code should be focused on the identified phenomena. Response surfaces are used in some applications replacing the computer code for performing a high number of calculations. The second well known uncertainty method is the Uncertainty Methodology Based on Accuracy Extrapolation (UMAE) and the follow-up method 'Code with the Capability of Internal Assessment of Uncertainty (CIAU)' developed by the University Pisa. Unlike the statistical approaches, the CIAU does compare experimental data with calculation results. It does not consider uncertain input parameters. Therefore, the CIAU is highly dependent on the experimental database. The accuracy gained from the comparison between experimental data and calculated results are extrapolated to obtain the uncertainty of the system code predictions 6. Linear mass reflectron Mamyrin, B.A.; Shmikk, D.V. 1979-01-01 A description and operating principle of a linear mass reflectron with V-form trajectory of ion motion -a new non-magnetic time-of-flight mass spectrometer with high resolution are presented. The ion-optical system of the device consists of an ion source with ionization by electron shock, of accelerating gaps, reflector gaps, a drift space and ion detector. Ions move in the linear mass refraction along the trajectories parallel to the axis of the analyzer chamber. The results of investigations into the experimental device are given. With an ion drift length of 0.6 m the device resolution is 1200 with respect to the peak width at half-height. Small-sized mass spectrometric transducers with high resolution and sensitivity may be designed on the base of the linear mass reflectron principle 7. Applied linear algebra Olver, Peter J 2018-01-01 This textbook develops the essential tools of linear algebra, with the goal of imparting technique alongside contextual understanding. Applications go hand-in-hand with theory, each reinforcing and explaining the other. This approach encourages students to develop not only the technical proficiency needed to go on to further study, but an appreciation for when, why, and how the tools of linear algebra can be used across modern applied mathematics. Providing an extensive treatment of essential topics such as Gaussian elimination, inner products and norms, and eigenvalues and singular values, this text can be used for an in-depth first course, or an application-driven second course in linear algebra. In this second edition, applications have been updated and expanded to include numerical methods, dynamical systems, data analysis, and signal processing, while the pedagogical flow of the core material has been improved. Throughout, the text emphasizes the conceptual connections between each application and the un... 8. Theory of linear operations Banach, S 1987-01-01 This classic work by the late Stefan Banach has been translated into English so as to reach a yet wider audience. It contains the basics of the algebra of operators, concentrating on the study of linear operators, which corresponds to that of the linear forms a1x1 + a2x2 + ... + anxn of algebra.The book gathers results concerning linear operators defined in general spaces of a certain kind, principally in Banach spaces, examples of which are: the space of continuous functions, that of the pth-power-summable functions, Hilbert space, etc. The general theorems are interpreted in various mathematical areas, such as group theory, differential equations, integral equations, equations with infinitely many unknowns, functions of a real variable, summation methods and orthogonal series.A new fifty-page section (Some Aspects of the Present Theory of Banach Spaces'''') complements this important monograph. 9. Dimension of linear models Høskuldsson, Agnar 1996-01-01 Determination of the proper dimension of a given linear model is one of the most important tasks in the applied modeling work. We consider here eight criteria that can be used to determine the dimension of the model, or equivalently, the number of components to use in the model. Four of these cri......Determination of the proper dimension of a given linear model is one of the most important tasks in the applied modeling work. We consider here eight criteria that can be used to determine the dimension of the model, or equivalently, the number of components to use in the model. Four...... the basic problems in determining the dimension of linear models. Then each of the eight measures are treated. The results are illustrated by examples.... 10. Linear Colliders TESLA Anon. 1994-01-01 The aim of the TESLA (TeV Superconducting Linear Accelerator) collaboration (at present 19 institutions from seven countries) is to establish the technology for a high energy electron-positron linear collider using superconducting radiofrequency cavities to accelerate its beams. Another basic goal is to demonstrate that such a collider can meet its performance goals in a cost effective manner. For this the TESLA collaboration is preparing a 500 MeV superconducting linear test accelerator at the DESY Laboratory in Hamburg. This TTF (TESLA Test Facility) consists of four cryomodules, each approximately 12 m long and containing eight 9-cell solid niobium cavities operating at a frequency of 1.3 GHz 11. Linearly Adjustable International Portfolios Fonseca, R. J.; Kuhn, D.; Rustem, B. 2010-09-01 We present an approach to multi-stage international portfolio optimization based on the imposition of a linear structure on the recourse decisions. Multiperiod decision problems are traditionally formulated as stochastic programs. Scenario tree based solutions however can become intractable as the number of stages increases. By restricting the space of decision policies to linear rules, we obtain a conservative tractable approximation to the original problem. Local asset prices and foreign exchange rates are modelled separately, which allows for a direct measure of their impact on the final portfolio value. 12. Linearly Adjustable International Portfolios Fonseca, R. J.; Kuhn, D.; Rustem, B. 2010-01-01 We present an approach to multi-stage international portfolio optimization based on the imposition of a linear structure on the recourse decisions. Multiperiod decision problems are traditionally formulated as stochastic programs. Scenario tree based solutions however can become intractable as the number of stages increases. By restricting the space of decision policies to linear rules, we obtain a conservative tractable approximation to the original problem. Local asset prices and foreign exchange rates are modelled separately, which allows for a direct measure of their impact on the final portfolio value. 13. Linear induction motor Barkman, W.E.; Adams, W.Q.; Berrier, B.R. 1978-01-01 A linear induction motor has been operated on a test bed with a feedback pulse resolution of 5 nm (0.2 μin). Slewing tests with this slide drive have shown positioning errors less than or equal to 33 nm (1.3 μin) at feedrates between 0 and 25.4 mm/min (0-1 ipm). A 0.86-m (34-in)-stroke linear motor is being investigated, using the SPACO machine as a test bed. Initial results were encouraging, and work is continuing to optimize the servosystem compensation 14. Handbook of linear algebra Hogben, Leslie 2013-01-01 With a substantial amount of new material, the Handbook of Linear Algebra, Second Edition provides comprehensive coverage of linear algebra concepts, applications, and computational software packages in an easy-to-use format. It guides you from the very elementary aspects of the subject to the frontiers of current research. Along with revisions and updates throughout, the second edition of this bestseller includes 20 new chapters.New to the Second EditionSeparate chapters on Schur complements, additional types of canonical forms, tensors, matrix polynomials, matrix equations, special types of 15. Linear Algebra Thoroughly Explained Vujičić, Milan 2008-01-01 Linear Algebra Thoroughly Explained provides a comprehensive introduction to the subject suitable for adoption as a self-contained text for courses at undergraduate and postgraduate level. The clear and comprehensive presentation of the basic theory is illustrated throughout with an abundance of worked examples. The book is written for teachers and students of linear algebra at all levels and across mathematics and the applied sciences, particularly physics and engineering. It will also be an invaluable addition to research libraries as a comprehensive resource book for the subject. 16. Sparsity Prevention Pivoting Method for Linear Programming Li, Peiqiang; Li, Qiyuan; Li, Canbing 2018-01-01 When the simplex algorithm is used to calculate a linear programming problem, if the matrix is a sparse matrix, it will be possible to lead to many zero-length calculation steps, and even iterative cycle will appear. To deal with the problem, a new pivoting method is proposed in this paper....... The principle of this method is avoided choosing the row which the value of the element in the b vector is zero as the row of the pivot element to make the matrix in linear programming density and ensure that most subsequent steps will improve the value of the objective function. One step following...... this principle is inserted to reselect the pivot element in the existing linear programming algorithm. Both the conditions for inserting this step and the maximum number of allowed insertion steps are determined. In the case study, taking several numbers of linear programming problems as examples, the results... 17. Sparsity Prevention Pivoting Method for Linear Programming Li, Peiqiang; Li, Qiyuan; Li, Canbing 2018-01-01 . The principle of this method is avoided choosing the row which the value of the element in the b vector is zero as the row of the pivot element to make the matrix in linear programming density and ensure that most subsequent steps will improve the value of the objective function. One step following......When the simplex algorithm is used to calculate a linear programming problem, if the matrix is a sparse matrix, it will be possible to lead to many zero-length calculation steps, and even iterative cycle will appear. To deal with the problem, a new pivoting method is proposed in this paper...... this principle is inserted to reselect the pivot element in the existing linear programming algorithm. Both the conditions for inserting this step and the maximum number of allowed insertion steps are determined. In the case study, taking several numbers of linear programming problems as examples, the results... 18. Linear and non-linear amplification of high-mode perturbations at the ablation front in HiPER targets Olazabal-Loume, M; Breil, J; Hallo, L; Ribeyre, X [CELIA, UMR 5107 Universite Bordeaux 1-CNRS-CEA, 351 cours de la Liberation, 33405 Talence (France); Sanz, J, E-mail: olazabal@celia.u-bordeaux1.f [ETSI Aeronauticos, Universidad Politecnica de Madrid, Madrid 28040 (Spain) 2011-01-15 The linear and non-linear sensitivity of the 180 kJ baseline HiPER target to high-mode perturbations, i.e. surface roughness, is addressed using two-dimensional simulations and a complementary analysis by linear and non-linear ablative Rayleigh-Taylor models. Simulations provide an assessment of an early non-linear stage leading to a significant deformation of the ablation surface for modes of maximum linear growth factor. A design using a picket prepulse evidences an improvement in the target stability inducing a delay of the non-linear behavior. Perturbation evolution and shape, evidenced by simulations of the non-linear stage, are analyzed with existing self-consistent non-linear theory. 19. Technical note: Avoiding the direct inversion of the numerator relationship matrix for genotyped animals in single-step genomic best linear unbiased prediction solved with the preconditioned conjugate gradient. Masuda, Y; Misztal, I; Legarra, A; Tsuruta, S; Lourenco, D A L; Fragomeni, B O; Aguilar, I 2017-01-01 This paper evaluates an efficient implementation to multiply the inverse of a numerator relationship matrix for genotyped animals () by a vector (). The computation is required for solving mixed model equations in single-step genomic BLUP (ssGBLUP) with the preconditioned conjugate gradient (PCG). The inverse can be decomposed into sparse matrices that are blocks of the sparse inverse of a numerator relationship matrix () including genotyped animals and their ancestors. The elements of were rapidly calculated with the Henderson's rule and stored as sparse matrices in memory. Implementation of was by a series of sparse matrix-vector multiplications. Diagonal elements of , which were required as preconditioners in PCG, were approximated with a Monte Carlo method using 1,000 samples. The efficient implementation of was compared with explicit inversion of with 3 data sets including about 15,000, 81,000, and 570,000 genotyped animals selected from populations with 213,000, 8.2 million, and 10.7 million pedigree animals, respectively. The explicit inversion required 1.8 GB, 49 GB, and 2,415 GB (estimated) of memory, respectively, and 42 s, 56 min, and 13.5 d (estimated), respectively, for the computations. The efficient implementation required <1 MB, 2.9 GB, and 2.3 GB of memory, respectively, and <1 sec, 3 min, and 5 min, respectively, for setting up. Only <1 sec was required for the multiplication in each PCG iteration for any data sets. When the equations in ssGBLUP are solved with the PCG algorithm, is no longer a limiting factor in the computations. 20. America, Linearly Cyclical 2013-05-10 AND VICTIM- ~ vAP BLAMING 4. AMERICA, LINEARLY CYCUCAL AF IMT 1768, 19840901, V5 PREVIOUS EDITION WILL BE USED. C2C Jessica Adams Dr. Brissett...his desires, his failings, and his aspirations follow the same general trend throughout history and throughout cultures. The founding fathers sought 1. Stanford's linear collider Southworth, B. 1985-01-01 The peak of the construction phase of the Stanford Linear Collider, SLC, to achieve 50 GeV electron-positron collisions has now been passed. The work remains on schedule to attempt colliding beams, initially at comparatively low luminosity, early in 1987. (orig./HSI). 2. Dosimetry of linear sources Mafra Neto, F. 1992-01-01 The dose of gamma radiation from a linear source of cesium 137 is obtained, presenting two difficulties: oblique filtration of radiation when cross the platinum wall, in different directions, and dose connection due to the scattering by the material mean of propagation. (C.G.C.) 3. Resistors Improve Ramp Linearity Kleinberg, L. L. 1982-01-01 Simple modification to bootstrap ramp generator gives more linear output over longer sweep times. New circuit adds just two resistors, one of which is adjustable. Modification cancels nonlinearities due to variations in load on charging capacitor and due to changes in charging current as the voltage across capacitor increases. 4. LINEAR COLLIDERS: 1992 workshop Settles, Ron; Coignet, Guy 1992-01-01 As work on designs for future electron-positron linear colliders pushes ahead at major Laboratories throughout the world in a major international collaboration framework, the LC92 workshop held in Garmisch Partenkirchen this summer, attended by 200 machine and particle physicists, provided a timely focus 5. Linear genetic programming Brameier, Markus 2007-01-01 Presents a variant of Genetic Programming that evolves imperative computer programs as linear sequences of instructions, in contrast to the more traditional functional expressions or syntax trees. This book serves as a reference for researchers, but also contains sufficient introduction for students and those who are new to the field 6. On Solving Linear Recurrences Dobbs, David E. 2013-01-01 A direct method is given for solving first-order linear recurrences with constant coefficients. The limiting value of that solution is studied as "n to infinity." This classroom note could serve as enrichment material for the typical introductory course on discrete mathematics that follows a calculus course. 7. Review of linear colliders Takeda, Seishi 1992-01-01 The status of R and D of future e + e - linear colliders proposed by the institutions throughout the world is described including the JLC, NLC, VLEPP, CLIC, DESY/THD and TESLA projects. The parameters and RF sources are discussed. (G.P.) 36 refs.; 1 tab 8. A relationship between solvent viscosity and biomolecule picosecond thermal fluctuations Cornicchi, E.; De Francesco, A.; Marconi, M.; Onori, G.; Paciaroni, A. 2008-01-01 Through elastic neutron scattering measurements, we investigated the picosecond dynamics of DNA in the hydrated powder state or embedded in glycerol glassy matrix from 20 K to 300 K. We calculated the relaxational contribution of the mean square displacements (MSD) of DNA hydrogen atoms. We found the existence of a linear relationship between the inverse of the biomolecule relaxational MSD and the logarithm of the bulk viscosity of the surrounding environment. From the comparison with the case of lysozyme in the same environments, for which the validity of the relationship was already verified, possible differences and analogies concerning the biomolecule-to-solvent dynamical coupling can be stressed 9. Linearity of holographic entanglement entropy Almheiri, Ahmed [Stanford Institute for Theoretical Physics, Department of Physics,Stanford University, Stanford, CA 94305 (United States); Dong, Xi [School of Natural Sciences, Institute for Advanced Study,Princeton, NJ 08540 (United States); Swingle, Brian [Stanford Institute for Theoretical Physics, Department of Physics,Stanford University, Stanford, CA 94305 (United States) 2017-02-14 We consider the question of whether the leading contribution to the entanglement entropy in holographic CFTs is truly given by the expectation value of a linear operator as is suggested by the Ryu-Takayanagi formula. We investigate this property by computing the entanglement entropy, via the replica trick, in states dual to superpositions of macroscopically distinct geometries and find it consistent with evaluating the expectation value of the area operator within such states. However, we find that this fails once the number of semi-classical states in the superposition grows exponentially in the central charge of the CFT. Moreover, in certain such scenarios we find that the choice of surface on which to evaluate the area operator depends on the density matrix of the entire CFT. This nonlinearity is enforced in the bulk via the homology prescription of Ryu-Takayanagi. We thus conclude that the homology constraint is not a linear property in the CFT. We also discuss the existence of ‘entropy operators’ in general systems with a large number of degrees of freedom. 10. Multiple linear regressions Abstract. The predictive analysis based on quantitative structure activity relationships (QSAR) on benzim- ... could lead to treatment of obesity, diabetes and related conditions. ..... After discussing the physical and chemical mean- ing of the ... 11. Competitive inhibition can linearize dose-response and generate a linear rectifier. Savir, Yonatan; Tu, Benjamin P; Springer, Michael 2015-09-23 Many biological responses require a dynamic range that is larger than standard bi-molecular interactions allow, yet the also ability to remain off at low input. Here we mathematically show that an enzyme reaction system involving a combination of competitive inhibition, conservation of the total level of substrate and inhibitor, and positive feedback can behave like a linear rectifier-that is, a network motif with an input-output relationship that is linearly sensitive to substrate above a threshold but unresponsive below the threshold. We propose that the evolutionarily conserved yeast SAGA histone acetylation complex may possess the proper physiological response characteristics and molecular interactions needed to perform as a linear rectifier, and we suggest potential experiments to test this hypothesis. One implication of this work is that linear responses and linear rectifiers might be easier to evolve or synthetically construct than is currently appreciated. 12. Econometric testing on linear and nonlinear dynamic relation between stock prices and macroeconomy in China Borjigin, Sumuya; Yang, Yating; Yang, Xiaoguang; Sun, Leilei 2018-03-01 Many researchers have realized that there is a strong correlation between stock prices and macroeconomy. In order to make this relationship clear, a lot of studies have been done. However, the causal relationship between stock prices and macroeconomy has still not been well explained. A key point is that, most of the existing research adopts linear and stable models to investigate the correlation of stock prices and macroeconomy, while the real causality of that may be nonlinear and dynamic. To fill this research gap, we investigate the nonlinear and dynamic causal relationships between stock prices and macroeconomy. Based on the case of China's stock prices and acroeconomy measures from January 1992 to March 2017, we compare the linear Granger causality test models with nonlinear ones. Results demonstrate that the nonlinear dynamic Granger causality is much stronger than linear Granger causality. From the perspective of nonlinear dynamic Granger causality, China's stock prices can be viewed as "national economic barometer". On the one hand, this study will encourage researchers to take nonlinearity and dynamics into account when they investigate the correlation of stock prices and macroeconomy; on the other hand, our research can guide regulators and investors to make better decisions. 13. The Non-Linear Effect of Corporate Taxes on Economic Growth Huňady Ján 2015-03-01 Full Text Available The paper deals with the problem of taxation and its potential impact on economic growth and presents some new empirical insights into this topic. The main aim of the paper is to verify an assumed nonlinear impact of corporate tax rates on economic growth. Based on the theory of public finance and taxation, we hypothesize that at relatively low tax rates it is possible that the impact of taxation on economic growth become slightly positive. On the other hand when the tax rates are higher a negative impact of taxation on economic growth could be expected. Despite the fact that the most of the existing studies find a negative linear relationship between these variables, we can also find strong support for a non-linear relationship from several theoretical models as well as some empirical studies. Based on panel data fixed-effects econometric models, we, as well, find empirical evidence for a non-linear relationship between nominal and effective corporate tax rates and economic growth. Our data consists of annual observations for the period 1999 to 2011 for EU Member States. Based on the results, we also estimated the optimal level of the corporate tax rate in terms of maximizing economic growth in the average of the EU countries. 14. Existence of weak solutions to stochastic evolution inclusions Jakubowski , Adam; Kamenskii , Mikhail; Raynaud de Fitte , Paul 2005-01-01 International audience; We consider the Cauchy problem for a semilinear stochastic differential inclusion in a Hilbert space. The linear operator generates a strongly continuous semigroup and the nonlinear term is multivalued and satisfies a condition which is more heneral than the Lipschitz condition. We prove the existence of a mild solution to this problem. This solution is not "strong" in the probabilistic sense, that is, it is not defined on the underlying probability space, but on a lar... 15. Linearity and Non-linearity of Photorefractive effect in Materials ... In this paper we have studied the Linearity and Non-linearity of Photorefractive effect in materials using the band transport model. For low light beam intensities the change in the refractive index is proportional to the electric field for linear optics while for non- linear optics the change in refractive index is directly proportional ... 16. Linearly Refined Session Types Pedro Baltazar 2012-11-01 Full Text Available Session types capture precise protocol structure in concurrent programming, but do not specify properties of the exchanged values beyond their basic type. Refinement types are a form of dependent types that can address this limitation, combining types with logical formulae that may refer to program values and can constrain types using arbitrary predicates. We present a pi calculus with assume and assert operations, typed using a session discipline that incorporates refinement formulae written in a fragment of Multiplicative Linear Logic. Our original combination of session and refinement types, together with the well established benefits of linearity, allows very fine-grained specifications of communication protocols in which refinement formulae are treated as logical resources rather than persistent truths. 17. Linear Water Waves Kuznetsov, N.; Maz'ya, V.; Vainberg, B. 2002-08-01 This book gives a self-contained and up-to-date account of mathematical results in the linear theory of water waves. The study of waves has many applications, including the prediction of behavior of floating bodies (ships, submarines, tension-leg platforms etc.), the calculation of wave-making resistance in naval architecture, and the description of wave patterns over bottom topography in geophysical hydrodynamics. The first section deals with time-harmonic waves. Three linear boundary value problems serve as the approximate mathematical models for these types of water waves. The next section uses a plethora of mathematical techniques in the investigation of these three problems. The techniques used in the book include integral equations based on Green's functions, various inequalities between the kinetic and potential energy and integral identities which are indispensable for proving the uniqueness theorems. The so-called inverse procedure is applied to constructing examples of non-uniqueness, usually referred to as 'trapped nodes.' 18. The International Linear Collider List Benno 2014-04-01 Full Text Available The International Linear Collider (ILC is a proposed e+e− linear collider with a centre-of-mass energy of 200–500 GeV, based on superconducting RF cavities. The ILC would be an ideal machine for precision studies of a light Higgs boson and the top quark, and would have a discovery potential for new particles that is complementary to that of LHC. The clean experimental conditions would allow the operation of detectors with extremely good performance; two such detectors, ILD and SiD, are currently being designed. Both make use of novel concepts for tracking and calorimetry. The Japanese High Energy Physics community has recently recommended to build the ILC in Japan. 19. The International Linear Collider List, Benno 2014-04-01 The International Linear Collider (ILC) is a proposed e+e- linear collider with a centre-of-mass energy of 200-500 GeV, based on superconducting RF cavities. The ILC would be an ideal machine for precision studies of a light Higgs boson and the top quark, and would have a discovery potential for new particles that is complementary to that of LHC. The clean experimental conditions would allow the operation of detectors with extremely good performance; two such detectors, ILD and SiD, are currently being designed. Both make use of novel concepts for tracking and calorimetry. The Japanese High Energy Physics community has recently recommended to build the ILC in Japan. 20. Dimension of linear models Høskuldsson, Agnar 1996-01-01 Determination of the proper dimension of a given linear model is one of the most important tasks in the applied modeling work. We consider here eight criteria that can be used to determine the dimension of the model, or equivalently, the number of components to use in the model. Four...... the basic problems in determining the dimension of linear models. Then each of the eight measures are treated. The results are illustrated by examples....... of these criteria are widely used ones, while the remaining four are ones derived from the H-principle of mathematical modeling. Many examples from practice show that the criteria derived from the H-principle function better than the known and popular criteria for the number of components. We shall briefly review... 1. Reciprocating linear motor Goldowsky, Michael P. (Inventor) 1987-01-01 A reciprocating linear motor is formed with a pair of ring-shaped permanent magnets having opposite radial polarizations, held axially apart by a nonmagnetic yoke, which serves as an axially displaceable armature assembly. A pair of annularly wound coils having axial lengths which differ from the axial lengths of the permanent magnets are serially coupled together in mutual opposition and positioned with an outer cylindrical core in axial symmetry about the armature assembly. One embodiment includes a second pair of annularly wound coils serially coupled together in mutual opposition and an inner cylindrical core positioned in axial symmetry inside the armature radially opposite to the first pair of coils. Application of a potential difference across a serial connection of the two pairs of coils creates a current flow perpendicular to the magnetic field created by the armature magnets, thereby causing limited linear displacement of the magnets relative to the coils. 2. Duality in linearized gravity Henneaux, Marc; Teitelboim, Claudio 2005-01-01 We show that duality transformations of linearized gravity in four dimensions, i.e., rotations of the linearized Riemann tensor and its dual into each other, can be extended to the dynamical fields of the theory so as to be symmetries of the action and not just symmetries of the equations of motion. Our approach relies on the introduction of two superpotentials, one for the spatial components of the spin-2 field and the other for their canonically conjugate momenta. These superpotentials are two-index, symmetric tensors. They can be taken to be the basic dynamical fields and appear locally in the action. They are simply rotated into each other under duality. In terms of the superpotentials, the canonical generator of duality rotations is found to have a Chern-Simons-like structure, as in the Maxwell case 3. The SLAC linear collider Phinney, N. 1992-01-01 The SLAC Linear Collider has begun a new era of operation with the SLD detector. During 1991 there was a first engineering run for the SLD in parallel with machine improvements to increase luminosity and reliability. For the 1992 run, a polarized electron source was added and more than 10,000 Zs with an average of 23% polarization have been logged by the SLD. This paper discusses the performance of the SLC in 1991 and 1992 and the technical advances that have produced higher luminosity. Emphasis will be placed on issues relevant to future linear colliders such as producing and maintaining high current, low emittance beams and focusing the beams to the micron scale for collisions. (Author) tab., 2 figs., 18 refs 4. Linear waves and instabilities Bers, A. 1975-01-01 The electrodynamic equations for small-amplitude waves and their dispersion relation in a homogeneous plasma are outlined. For such waves, energy and momentum, and their flow and transformation, are described. Perturbation theory of waves is treated and applied to linear coupling of waves, and the resulting instabilities from such interactions between active and passive waves. Linear stability analysis in time and space is described where the time-asymptotic, time-space Green's function for an arbitrary dispersion relation is developed. The perturbation theory of waves is applied to nonlinear coupling, with particular emphasis on pump-driven interactions of waves. Details of the time--space evolution of instabilities due to coupling are given. (U.S.) 5. Extended linear chain compounds Linear chain substances span a large cross section of contemporary chemistry ranging from covalent polymers, to organic charge transfer com­ plexes to nonstoichiometric transition metal coordination complexes. Their commonality, which coalesced intense interest in the theoretical and exper­ imental solid state physics/chemistry communities, was based on the obser­ vation that these inorganic and organic polymeric substrates exhibit striking metal-like electrical and optical properties. Exploitation and extension of these systems has led to the systematic study of both the chemistry and physics of highly and poorly conducting linear chain substances. To gain a salient understanding of these complex materials rich in anomalous aniso­ tropic electrical, optical, magnetic, and mechanical properties, the conver­ gence of diverse skills and talents was required. The constructive blending of traditionally segregated disciplines such as synthetic and physical organic, inorganic, and polymer chemistry, crystallog... 6. Non-linear osmosis Diamond, Jared M. 1966-01-01 1. The relation between osmotic gradient and rate of osmotic water flow has been measured in rabbit gall-bladder by a gravimetric procedure and by a rapid method based on streaming potentials. Streaming potentials were directly proportional to gravimetrically measured water fluxes. 2. As in many other tissues, water flow was found to vary with gradient in a markedly non-linear fashion. There was no consistent relation between the water permeability and either the direction or the rate of water flow. 3. Water flow in response to a given gradient decreased at higher osmolarities. The resistance to water flow increased linearly with osmolarity over the range 186-825 m-osM. 4. The resistance to water flow was the same when the gall-bladder separated any two bathing solutions with the same average osmolarity, regardless of the magnitude of the gradient. In other words, the rate of water flow is given by the expression (Om — Os)/[Ro′ + ½k′ (Om + Os)], where Ro′ and k′ are constants and Om and Os are the bathing solution osmolarities. 5. Of the theories advanced to explain non-linear osmosis in other tissues, flow-induced membrane deformations, unstirred layers, asymmetrical series-membrane effects, and non-osmotic effects of solutes could not explain the results. However, experimental measurements of water permeability as a function of osmolarity permitted quantitative reconstruction of the observed water flow—osmotic gradient curves. Hence non-linear osmosis in rabbit gall-bladder is due to a decrease in water permeability with increasing osmolarity. 6. The results suggest that aqueous channels in the cell membrane behave as osmometers, shrinking in concentrated solutions of impermeant molecules and thereby increasing membrane resistance to water flow. A mathematical formulation of such a membrane structure is offered. PMID:5945254 7. Fundamentals of linear algebra Dash, Rajani Ballav 2008-01-01 FUNDAMENTALS OF LINEAR ALGEBRA is a comprehensive Text Book, which can be used by students and teachers of All Indian Universities. The Text has easy, understandable form and covers all topics of UGC Curriculum. There are lots of worked out examples which helps the students in solving the problems without anybody's help. The Problem sets have been designed keeping in view of the questions asked in different examinations. 8. Linear network theory Sander, K F 1964-01-01 Linear Network Theory covers the significant algebraic aspect of network theory, with minimal reference to practical circuits. The book begins the presentation of network analysis with the exposition of networks containing resistances only, and follows it up with a discussion of networks involving inductance and capacity by way of the differential equations. Classification and description of certain networks, equivalent networks, filter circuits, and network functions are also covered. Electrical engineers, technicians, electronics engineers, electricians, and students learning the intricacies 9. Non linear viscoelastic models Agerkvist, Finn T. 2011-01-01 Viscoelastic eects are often present in loudspeaker suspensions, this can be seen in the displacement transfer function which often shows a frequency dependent value below the resonance frequency. In this paper nonlinear versions of the standard linear solid model (SLS) are investigated....... The simulations show that the nonlinear version of the Maxwell SLS model can result in a time dependent small signal stiness while the Kelvin Voight version does not.... 10. Relativistic Linear Restoring Force Clark, D.; Franklin, J.; Mann, N. 2012-01-01 We consider two different forms for a relativistic version of a linear restoring force. The pair comes from taking Hooke's law to be the force appearing on the right-hand side of the relativistic expressions: d"p"/d"t" or d"p"/d["tau"]. Either formulation recovers Hooke's law in the non-relativistic limit. In addition to these two forces, we… 11. Superconducting linear colliders Anon. 1990-01-01 The advantages of superconducting radiofrequency (SRF) for particle accelerators have been demonstrated by successful operation of systems in the TRISTAN and LEP electron-positron collider rings respectively at the Japanese KEK Laboratory and at CERN. If performance continues to improve and costs can be lowered, this would open an attractive option for a high luminosity TeV (1000 GeV) linear collider 12. Miniature linear cooler development Pruitt, G.R. 1993-01-01 An overview is presented of the status of a family of miniature linear coolers currently under development by Hughes Aircraft Co. for use in hand held, volume limited or power limited infrared applications. These coolers, representing the latest additions to the Hughes family of TOP trademark [twin-opposed piston] linear coolers, have been fabricated and tested in three different configurations. Each configuration is designed to utilize a common compressor assembly resulting in reduced manufacturing costs. The baseline compressor has been integrated with two different expander configurations and has been operated with two different levels of input power. These various configuration combinations offer a wide range of performance and interface characteristics which may be tailored to applications requiring limited power and size without significantly compromising cooler capacity or cooldown characteristics. Key cooler characteristics and test data are summarized for three combinations of cooler configurations which are representative of the versatility of this linear cooler design. Configurations reviewed include the shortened coldfinger [1.50 to 1.75 inches long], limited input power [less than 17 Watts] for low power availability applications; the shortened coldfinger with higher input power for lightweight, higher performance applications; and coldfingers compatible with DoD 0.4 Watt Common Module coolers for wider range retrofit capability. Typical weight of these miniature linear coolers is less than 500 grams for the compressor, expander and interconnecting transfer line. Cooling capacity at 80K at room ambient conditions ranges from 400 mW to greater than 550 mW. Steady state power requirements for maintaining a heat load of 150 mW at 80K has been shown to be less than 8 Watts. Ongoing reliability growth testing is summarized including a review of the latest test article results 13. Linear pneumatic actuator Avram Mihai 2017-01-01 Full Text Available The paper presents a linear pneumatic actuator with short working stroke. It consists of a pneumatic motor (a simple stroke cylinder or a membrane chamber, two 2/2 pneumatic distributors “all or nothing” electrically commanded for controlling the intake/outtake flow to/from the active chamber of the motor, a position transducer and a microcontroller. There is also presented the theoretical analysis (mathematical modelling and numerical simulation accomplished. 14. Linear pneumatic actuator Avram Mihai; Niţu Constantin; Bucşan Constantin; Grămescu Bogdan 2017-01-01 The paper presents a linear pneumatic actuator with short working stroke. It consists of a pneumatic motor (a simple stroke cylinder or a membrane chamber), two 2/2 pneumatic distributors “all or nothing” electrically commanded for controlling the intake/outtake flow to/from the active chamber of the motor, a position transducer and a microcontroller. There is also presented the theoretical analysis (mathematical modelling and numerical simulation) accomplished. 15. Linear MHD equilibria Scheffel, J. 1984-03-01 The linear Grad-Shafranov equation for a toroidal, axisymmetric plasma is solved analytically. Exact solutions are given in terms of confluent hyper-geometric functions. As an alternative, simple and accurate WKBJ solutions are presented. With parabolic pressure profiles, both hollow and peaked toroidal current density profiles are obtained. As an example the equilibrium of a z-pinch with a square-shaped cross section is derived.(author) 16. Linear induction accelerator Buttram, M.T.; Ginn, J.W. 1988-06-21 A linear induction accelerator includes a plurality of adder cavities arranged in a series and provided in a structure which is evacuated so that a vacuum inductance is provided between each adder cavity and the structure. An energy storage system for the adder cavities includes a pulsed current source and a respective plurality of bipolar converting networks connected thereto. The bipolar high-voltage, high-repetition-rate square pulse train sets and resets the cavities. 4 figs. 17. International symposium on seismic evaluation of existing nuclear facilities Orbovic, N.; Bouchon, M. [Institut de Radioprotection et de Surete Nucleaire, IRSN, 92 - Fontenay aux Roses (France); Vendel, J.; Gelain, T. [IRSN/DPEA/SERAC, 91 - Gif sur Yvette (France) 2003-10-01 Below are summarized the works of Mrs N. Orbovic and M. Bouchon; B. Stojadinovic, N. Orbovic, M.Bouchon and J.T. Wiley; M. Bouchon, N. Orbovic and B. Foure; T. Gelain, F. Gensdarmes, R. Sestier-Carlin, J. Vendel and M. Bouchon dealing respectively with: 1) seismic assessment of existing nuclear facility: a case study position of the IRSN 2) static and dynamic evaluation of an existing nuclear facility reinforced concrete frame structure 3) experimental study of cracking of low-rise reinforced concrete shear walls 4) aeraulics study of crack networks on low-rise reinforced concrete walls subject to static cycling loading. The summaries are followed: 1) The Institute for Radioprotection and Nuclear Safety (IRSN) has the task of evaluating the seismic safety of existing building inventory in French nuclear facilities. Some of the existing structures are reinforced concrete frame buildings with masonry or reinforced concrete in-fill walls built during the 1960's, 70's and 80's following different building codes and seismic input data applicable at the time of construction. The studied building is a laboratory that was built in 1962. The building is composed of three different and independent blocks. The structure is a reinforced concrete frame with masonry in-fills and few stiff concrete elements. Moreover, the building contains an independent massive concrete cell. Structurally, the building has a number of irregularities. From the detailing standpoint, well known deficiencies of low-ductile reinforced concrete structures are evident especially, a lack of transverse reinforcement in the structural joints of the frame. A number of sensitivity studies were conducted using 2D and 3D linear models to evaluate seismic demand. Ambient vibration and regional earthquake records were used to check the soil nature and the existence or not of a possible site effect around the installation as well as to characterize the dynamic behavior of the building. 3D models 18. International symposium on seismic evaluation of existing nuclear facilities Orbovic, N.; Bouchon, M.; Vendel, J.; Gelain, T. 2003-10-01 Below are summarized the works of Mrs N. Orbovic and M. Bouchon; B. Stojadinovic, N. Orbovic, M.Bouchon and J.T. Wiley; M. Bouchon, N. Orbovic and B. Foure; T. Gelain, F. Gensdarmes, R. Sestier-Carlin, J. Vendel and M. Bouchon dealing respectively with: 1) seismic assessment of existing nuclear facility: a case study position of the IRSN 2) static and dynamic evaluation of an existing nuclear facility reinforced concrete frame structure 3) experimental study of cracking of low-rise reinforced concrete shear walls 4) aeraulics study of crack networks on low-rise reinforced concrete walls subject to static cycling loading. The summaries are followed: 1) The Institute for Radioprotection and Nuclear Safety (IRSN) has the task of evaluating the seismic safety of existing building inventory in French nuclear facilities. Some of the existing structures are reinforced concrete frame buildings with masonry or reinforced concrete in-fill walls built during the 1960's, 70's and 80's following different building codes and seismic input data applicable at the time of construction. The studied building is a laboratory that was built in 1962. The building is composed of three different and independent blocks. The structure is a reinforced concrete frame with masonry in-fills and few stiff concrete elements. Moreover, the building contains an independent massive concrete cell. Structurally, the building has a number of irregularities. From the detailing standpoint, well known deficiencies of low-ductile reinforced concrete structures are evident especially, a lack of transverse reinforcement in the structural joints of the frame. A number of sensitivity studies were conducted using 2D and 3D linear models to evaluate seismic demand. Ambient vibration and regional earthquake records were used to check the soil nature and the existence or not of a possible site effect around the installation as well as to characterize the dynamic behavior of the building. 3D models revealed a 19. Linear algebraic groups Springer, T A 1998-01-01 "[The first] ten chapters...are an efficient, accessible, and self-contained introduction to affine algebraic groups over an algebraically closed field. The author includes exercises and the book is certainly usable by graduate students as a text or for self-study...the author [has a] student-friendly style… [The following] seven chapters... would also be a good introduction to rationality issues for algebraic groups. A number of results from the literature…appear for the first time in a text." –Mathematical Reviews (Review of the Second Edition) "This book is a completely new version of the first edition. The aim of the old book was to present the theory of linear algebraic groups over an algebraically closed field. Reading that book, many people entered the research field of linear algebraic groups. The present book has a wider scope. Its aim is to treat the theory of linear algebraic groups over arbitrary fields. Again, the author keeps the treatment of prerequisites self-contained. The material of t... 20. Parametric Linear Dynamic Logic Peter Faymonville 2014-08-01 Full Text Available We introduce Parametric Linear Dynamic Logic (PLDL, which extends Linear Dynamic Logic (LDL by temporal operators equipped with parameters that bound their scope. LDL was proposed as an extension of Linear Temporal Logic (LTL that is able to express all ω-regular specifications while still maintaining many of LTL's desirable properties like an intuitive syntax and a translation into non-deterministic Büchi automata of exponential size. But LDL lacks capabilities to express timing constraints. By adding parameterized operators to LDL, we obtain a logic that is able to express all ω-regular properties and that subsumes parameterized extensions of LTL like Parametric LTL and PROMPT-LTL. Our main technical contribution is a translation of PLDL formulas into non-deterministic Büchi word automata of exponential size via alternating automata. This yields a PSPACE model checking algorithm and a realizability algorithm with doubly-exponential running time. Furthermore, we give tight upper and lower bounds on optimal parameter values for both problems. These results show that PLDL model checking and realizability are not harder than LTL model checking and realizability. 1. Quantum linear Boltzmann equation Vacchini, Bassano; Hornberger, Klaus 2009-01-01 We review the quantum version of the linear Boltzmann equation, which describes in a non-perturbative fashion, by means of scattering theory, how the quantum motion of a single test particle is affected by collisions with an ideal background gas. A heuristic derivation of this Lindblad master equation is presented, based on the requirement of translation-covariance and on the relation to the classical linear Boltzmann equation. After analyzing its general symmetry properties and the associated relaxation dynamics, we discuss a quantum Monte Carlo method for its numerical solution. We then review important limiting forms of the quantum linear Boltzmann equation, such as the case of quantum Brownian motion and pure collisional decoherence, as well as the application to matter wave optics. Finally, we point to the incorporation of quantum degeneracies and self-interactions in the gas by relating the equation to the dynamic structure factor of the ambient medium, and we provide an extension of the equation to include internal degrees of freedom. 2. The Stanford Linear Collider Emma, P. 1995-01-01 The Stanford Linear Collider (SLC) is the first and only high-energy e + e - linear collider in the world. Its most remarkable features are high intensity, submicron sized, polarized (e - ) beams at a single interaction point. The main challenges posed by these unique characteristics include machine-wide emittance preservation, consistent high intensity operation, polarized electron production and transport, and the achievement of a high degree of beam stability on all time scales. In addition to serving as an important machine for the study of Z 0 boson production and decay using polarized beams, the SLC is also an indispensable source of hands-on experience for future linear colliders. Each new year of operation has been highlighted with a marked improvement in performance. The most significant improvements for the 1994-95 run include new low impedance vacuum chambers for the damping rings, an upgrade to the optics and diagnostics of the final focus systems, and a higher degree of polarization from the electron source. As a result, the average luminosity has nearly doubled over the previous year with peaks approaching 10 30 cm -2 s -1 and an 80% electron polarization at the interaction point. These developments as well as the remaining identifiable performance limitations will be discussed 3. Available pressure amplitude of linear compressor based on phasor triangle model Duan, C. X.; Jiang, X.; Zhi, X. Q.; You, X. K.; Qiu, L. M. 2017-12-01 The linear compressor for cryocoolers possess the advantages of long-life operation, high efficiency, low vibration and compact structure. It is significant to study the match mechanisms between the compressor and the cold finger, which determines the working efficiency of the cryocooler. However, the output characteristics of linear compressor are complicated since it is affected by many interacting parameters. The existing matching methods are simplified and mainly focus on the compressor efficiency and output acoustic power, while neglecting the important output parameter of pressure amplitude. In this study, a phasor triangle model basing on analyzing the forces of the piston is proposed. It can be used to predict not only the output acoustic power, the efficiency, but also the pressure amplitude of the linear compressor. Calculated results agree well with the measurement results of the experiment. By this phasor triangle model, the theoretical maximum output pressure amplitude of the linear compressor can be calculated simply based on a known charging pressure and operating frequency. Compared with the mechanical and electrical model of the linear compressor, the new model can provide an intuitionistic understanding on the match mechanism with faster computational process. The model can also explain the experimental phenomenon of the proportional relationship between the output pressure amplitude and the piston displacement in experiments. By further model analysis, such phenomenon is confirmed as an expression of the unmatched design of the compressor. The phasor triangle model may provide an alternative method for the compressor design and matching with the cold finger. 4. Scattering theory of the linear Boltzmann operator Hejtmanek, J. 1975-01-01 In time dependent scattering theory we know three important examples: the wave equation around an obstacle, the Schroedinger and the Dirac equation with a scattering potential. In this paper another example from time dependent linear transport theory is added and considered in full detail. First the linear Boltzmann operator in certain Banach spaces is rigorously defined, and then the existence of the Moeller operators is proved by use of the theorem of Cook-Jauch-Kuroda, that is generalized to the case of a Banach space. (orig.) [de 5. Generalized Cross-Gramian for Linear Systems Shaker, Hamid Reza 2012-01-01 The cross-gramian is a well-known matrix with embedded controllability and observability information. The cross-gramian is related to the Hankel operator and the Hankel singular values of a linear square system and it has several interesting properties. These properties make the cross...... square symmetric systems, the ordinary cross-gramian does not exist. To cope with this problem, a new generalized cross-gramian is introduced in this paper. In contrast to the ordinary cross-gramian, the generalized cross-gramian can be easily obtained for general linear systems and therefore can be used... 6. The simplex method of linear programming Ficken, Frederick A 1961-01-01 This concise but detailed and thorough treatment discusses the rudiments of the well-known simplex method for solving optimization problems in linear programming. Geared toward undergraduate students, the approach offers sufficient material for readers without a strong background in linear algebra. Many different kinds of problems further enrich the presentation. The text begins with examinations of the allocation problem, matrix notation for dual problems, feasibility, and theorems on duality and existence. Subsequent chapters address convex sets and boundedness, the prepared problem and boun 7. Use of linear discriminant function analysis in seed morphotype ... Use of linear discriminant function analysis in seed morphotype relationship study in 31 ... Data were collected on 100-seed weight, seed length and seed width. ... to the Mesoamerican gene pool, comprising the cultigroups Sieva-Big Lima, ... 8. Distributed Monitoring of the R2 Statistic for Linear Regression National Aeronautics and Space Administration — The problem of monitoring a multivariate linear regression model is relevant in studying the evolving relationship between a set of input variables (features) and... 9. Near-Regular Structure Discovery Using Linear Programming Huang, Qixing; Guibas, Leonidas J.; Mitra, Niloy J. 2014-01-01 as an optimization and efficiently solve it using linear programming techniques. Our optimization has a discrete aspect, that is, the connectivity relationships among the elements, as well as a continuous aspect, namely the locations of the elements of interest. Both 10. 10 CFR 4.127 - Existing facilities. 2010-01-01 ... 10 Energy 1 2010-01-01 2010-01-01 false Existing facilities. 4.127 Section 4.127 Energy NUCLEAR... 1973, as Amended Discriminatory Practices § 4.127 Existing facilities. (a) Accessibility. A recipient... make each of its existing facilities or every part of an existing facility accessible to and usable by... 11. Students’ difficulties in solving linear equation problems Wati, S.; Fitriana, L.; Mardiyana 2018-03-01 A linear equation is an algebra material that exists in junior high school to university. It is a very important material for students in order to learn more advanced mathematics topics. Therefore, linear equation material is essential to be mastered. However, the result of 2016 national examination in Indonesia showed that students’ achievement in solving linear equation problem was low. This fact became a background to investigate students’ difficulties in solving linear equation problems. This study used qualitative descriptive method. An individual written test on linear equation tasks was administered, followed by interviews. Twenty-one sample students of grade VIII of SMPIT Insan Kamil Karanganyar did the written test, and 6 of them were interviewed afterward. The result showed that students with high mathematics achievement donot have difficulties, students with medium mathematics achievement have factual difficulties, and students with low mathematics achievement have factual, conceptual, operational, and principle difficulties. Based on the result there is a need of meaningfulness teaching strategy to help students to overcome difficulties in solving linear equation problems. 12. Linear approximation model network and its formation via ... niques, an alternative `linear approximation model' (LAM) network approach is .... network is LPV, existing LTI theory is difficult to apply (Kailath 1980). ..... Beck J V, Arnold K J 1977 Parameter estimation in engineering and science (New York: ... 13. Impact self-excited vibrations of linear motor Zhuravlev, V. Ph. 2010-08-01 Impact self-exciting vibration modes in a linear motor of a monorail car are studied. Existence and stability conditions of self-exciting vibrations are found. Ways of avoiding the vibrations are discussed. 14. On a non-linear pseudodifferential boundary value problem Nguyen Minh Chuong. 1989-12-01 A pseudodifferential boundary value problem for operators with symbols taking values in Sobolev spaces and with non-linear right-hand side was studied. Existence and uniqueness theorems were proved. (author). 11 refs 15. (Non) linear regression modelling Cizek, P.; Gentle, J.E.; Hardle, W.K.; Mori, Y. 2012-01-01 We will study causal relationships of a known form between random variables. Given a model, we distinguish one or more dependent (endogenous) variables Y = (Y1,…,Yl), l ∈ N, which are explained by a model, and independent (exogenous, explanatory) variables X = (X1,…,Xp),p ∈ N, which explain or 16. A Proposed Method for Solving Fuzzy System of Linear Equations Reza Kargar 2014-01-01 Full Text Available This paper proposes a new method for solving fuzzy system of linear equations with crisp coefficients matrix and fuzzy or interval right hand side. Some conditions for the existence of a fuzzy or interval solution of m×n linear system are derived and also a practical algorithm is introduced in detail. The method is based on linear programming problem. Finally the applicability of the proposed method is illustrated by some numerical examples. 17. Non linear microtearing modes Garbet, X.; Mourgues, F.; Samain, A. 1987-01-01 Among the various instabilities which could explain the anomalous electron heat transport observed in tokamaks during additional heating, a microtearing turbulence is a reasonable candidate since it affects directly the magnetic topology. This turbulence may be described in a proper frame rotating around the majors axis by a static potential vector. In strong non linear regimes, the flow of electrons along the stochastic field lines induces a current. The point is to know whether this current can sustain the turbulence. The mechanisms of this self-consistency, involving the combined effects of the thermal diamagnetism and of the electric drift are presented here 18. RF linear accelerators Wangler, Thomas P 2008-01-01 Thomas P. Wangler received his B.S. degree in physics from Michigan State University, and his Ph.D. degree in physics and astronomy from the University of Wisconsin. After postdoctoral appointments at the University of Wisconsin and Brookhaven National Laboratory, he joined the staff of Argonne National Laboratory in 1966, working in the fields of experimental high-energy physics and accelerator physics. He joined the Accelerator Technology Division at Los Alamos National Laboratory in 1979, where he specialized in high-current beam physics and linear accelerator design and technology. In 2007 19. SLAC linear collider Richter, B.; Bell, R.A.; Brown, K.L. 1980-06-01 The SLAC LINEAR COLLIDER is designed to achieve an energy of 100 GeV in the electron-positron center-of-mass system by accelerating intense bunches of particles in the SLAC linac and transporting the electron and positron bunches in a special magnet system to a point where they are focused to a radius of about 2 microns and made to collide head on. The rationale for this new type of colliding beam system is discussed, the project is described, some of the novel accelerator physics issues involved are discussed, and some of the critical technical components are described 20. Matlab linear algebra Lopez, Cesar 2014-01-01 MATLAB is a high-level language and environment for numerical computation, visualization, and programming. Using MATLAB, you can analyze data, develop algorithms, and create models and applications. The language, tools, and built-in math functions enable you to explore multiple approaches and reach a solution faster than with spreadsheets or traditional programming languages, such as C/C++ or Java. MATLAB Linear Algebra introduces you to the MATLAB language with practical hands-on instructions and results, allowing you to quickly achieve your goals. In addition to giving an introduction to 1. Partial Linearization of Mechanical Systems with Application to Observer Design Sarras, Ioannis; Venkatraman, Aneesh; Ortega, Romeo; Schaft, Arjan van der 2008-01-01 We consider general mechanical systems and establish a necessary and sufficient condition for the existence of a suitable change in the generalized momentum coordinates such that the new dynamics become linear in the transformed momenta. The class of systems which can be (partially) linearized by 2. Existence and Uniqueness of Solution of Schrodinger equation in extended Colombeau algebra Fariba Fattahi 2014-09-01 Full Text Available In this paper, we establish the existence and uniquenessresult of the linear Schr¨odinger equation with Marchaudfractional derivative in Colombeau generalized algebra.The purpose of introducing Marchaud fractional derivativeis regularizing it in Colombeau sense. 3. A Design of Mechanical Frequency Converter Linear and Non-linear Spring Combination for Energy Harvesting Yamamoto, K; Fujita, T; Kanda, K; Maenaka, K; Badel, A; Formosa, F 2014-01-01 In this study, the improvement of energy harvesting from wideband vibration with random change by using a combination of linear and nonlinear spring system is investigated. The system consists of curved beam spring for non-linear buckling, which supports the linear mass-spring resonator. Applying shock acceleration generates a snap through action to the buckling spring. From the FEM analysis, we showed that the snap through acceleration from the buckling action has no relationship with the applied shock amplitude and duration. We use this uniform acceleration as an impulse shock source for the linear resonator. It is easy to obtain the maximum shock response from the uniform snap through acceleration by using a shock response spectrum (SRS) analysis method. At first we investigated the relationship between the snap-through behaviour and an initial curved deflection. Then a time response result for non-linear springs with snap through and minimum force that makes a buckling behaviour were obtained by FEM analysis. By obtaining the optimum SRS frequency for linear resonator, we decided its resonant frequency with the MATLAB simulator 4. Optical surfacing via linear ion source Wu, Lixiang; Wei, Chaoyang; Shao, Jianda 2017-01-01 We present a concept of surface decomposition extended from double Fourier series to nonnegative sinusoidal wave surfaces, on the basis of which linear ion sources apply to the ultra-precision fabrication of complex surfaces and diffractive optics. The modified Fourier series, or sinusoidal wave surfaces, build a relationship between the fabrication process of optical surfaces and the surface characterization based on power spectral density (PSD) analysis. Also, we demonstrate that the one-dimensional scanning of linear ion source is applicable to the removal of mid-spatial frequency (MSF) errors caused by small-tool polishing in raster scan mode as well as the fabrication of beam sampling grating of high diffractive uniformity without a post-processing procedure. The simulation results show that optical fabrication with linear ion source is feasible and even of higher output efficiency compared with the conventional approach. 5. Optical surfacing via linear ion source Wu, Lixiang, E-mail: wulx@hdu.edu.cn [Key Lab of RF Circuits and Systems of Ministry of Education, Zhejiang Provincial Key Lab of LSI Design, Microelectronics CAD Center, College of Electronics and Information, Hangzhou Dianzi University, Hangzhou (China); Wei, Chaoyang, E-mail: siomwei@siom.ac.cn [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Shao, Jianda, E-mail: jdshao@siom.ac.cn [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China) 2017-04-15 We present a concept of surface decomposition extended from double Fourier series to nonnegative sinusoidal wave surfaces, on the basis of which linear ion sources apply to the ultra-precision fabrication of complex surfaces and diffractive optics. The modified Fourier series, or sinusoidal wave surfaces, build a relationship between the fabrication process of optical surfaces and the surface characterization based on power spectral density (PSD) analysis. Also, we demonstrate that the one-dimensional scanning of linear ion source is applicable to the removal of mid-spatial frequency (MSF) errors caused by small-tool polishing in raster scan mode as well as the fabrication of beam sampling grating of high diffractive uniformity without a post-processing procedure. The simulation results show that optical fabrication with linear ion source is feasible and even of higher output efficiency compared with the conventional approach. 6. The topology of non-linear global carbon dynamics: from tipping points to planetary boundaries Anderies, J M; Carpenter, S R; Steffen, Will; Rockström, Johan 2013-01-01 We present a minimal model of land use and carbon cycle dynamics and use it to explore the relationship between non-linear dynamics and planetary boundaries. Only the most basic interactions between land cover and terrestrial, atmospheric, and marine carbon stocks are considered in the model. Our goal is not to predict global carbon dynamics as it occurs in the actual Earth System. Rather, we construct a conceptually reasonable heuristic model of a feedback system between different carbon stocks that captures the qualitative features of the actual Earth System and use it to explore the topology of the boundaries of what can be called a ‘safe operating space’ for humans. The model analysis illustrates the existence of dynamic, non-linear tipping points in carbon cycle dynamics and the potential complexity of planetary boundaries. Finally, we use the model to illustrate some challenges associated with navigating planetary boundaries. (letter) 7. The topology of non-linear global carbon dynamics: from tipping points to planetary boundaries Anderies, J. M.; Carpenter, S. R.; Steffen, Will; Rockström, Johan 2013-12-01 We present a minimal model of land use and carbon cycle dynamics and use it to explore the relationship between non-linear dynamics and planetary boundaries. Only the most basic interactions between land cover and terrestrial, atmospheric, and marine carbon stocks are considered in the model. Our goal is not to predict global carbon dynamics as it occurs in the actual Earth System. Rather, we construct a conceptually reasonable heuristic model of a feedback system between different carbon stocks that captures the qualitative features of the actual Earth System and use it to explore the topology of the boundaries of what can be called a ‘safe operating space’ for humans. The model analysis illustrates the existence of dynamic, non-linear tipping points in carbon cycle dynamics and the potential complexity of planetary boundaries. Finally, we use the model to illustrate some challenges associated with navigating planetary boundaries. 8. A Low-Complexity ESPRIT-Based DOA Estimation Method for Co-Prime Linear Arrays. Sun, Fenggang; Gao, Bin; Chen, Lizhen; Lan, Peng 2016-08-25 The problem of direction-of-arrival (DOA) estimation is investigated for co-prime array, where the co-prime array consists of two uniform sparse linear subarrays with extended inter-element spacing. For each sparse subarray, true DOAs are mapped into several equivalent angles impinging on the traditional uniform linear array with half-wavelength spacing. Then, by applying the estimation of signal parameters via rotational invariance technique (ESPRIT), the equivalent DOAs are estimated, and the candidate DOAs are recovered according to the relationship among equivalent and true DOAs. Finally, the true DOAs are estimated by combining the results of the two subarrays. The proposed method achieves a better complexity-performance tradeoff as compared to other existing methods. 9. A New Theory of Non-Linear Thermo-Elastic Constitutive Equation of Isotropic Hyperelastic Materials Li, Chen; Liao, Yufei 2018-03-01 Considering the influence of temperature and strain variables on materials. According to the relationship of conjugate stress-strain, a complete and irreducible non-linear constitutive equation of isotropic hyperelastic materials is derived and the constitutive equations of 16 types of isotropic hyperelastic materials are given we study the transformation methods and routes of 16 kinds of constitutive equations and the study proves that transformation of two forms of constitutive equation. As an example of application, the non-linear thermo-elastic constitutive equation of isotropic hyperelastic materials is combined with the natural vulcanized rubber experimental data in the existing literature base on MATLAB, The results show that the fitting accuracy is satisfactory. 10. Special set linear algebra and special set fuzzy linear algebra Kandasamy, W. B. Vasantha; Smarandache, Florentin; Ilanthenral, K. 2009-01-01 The authors in this book introduce the notion of special set linear algebra and special set fuzzy Linear algebra, which is an extension of the notion set linear algebra and set fuzzy linear algebra. These concepts are best suited in the application of multi expert models and cryptology. This book has five chapters. In chapter one the basic concepts about set linear algebra is given in order to make this book a self contained one. The notion of special set linear algebra and their fuzzy analog... 11. Electrodynamic linear motor Munehiro, H 1980-05-29 When driving the carriage of a printer through a rotating motor, there are problems regarding the limited accuracy of the carriage position due to rotation or contraction and ageing of the cable. In order to solve the problem, a direct drive system was proposed, in which the printer carriage is driven by a linear motor. If one wants to keep the motor circuit of such a motor compact, then the magnetic flux density in the air gap must be reduced or the motor travel must be reduced. It is the purpose of this invention to create an electrodynamic linear motor, which on the one hand is compact and light and on the other hand has a relatively high constant force over a large travel. The invention is characterised by the fact that magnetic fields of alternating polarity are generated at equal intervals in the magnetic field, and that the coil arrangement has 2 adjacent coils, whose size corresponds to half the length of each magnetic pole. A logic circuit is provided to select one of the two coils and to determine the direction of the current depending on the signals of a magnetic field sensor on the coil arrangement. 12. Linear quadratic Gaussian balancing for discrete-time infinite-dimensional linear systems Opmeer, MR; Curtain, RF 2004-01-01 In this paper, we study the existence of linear quadratic Gaussian (LQG)-balanced realizations for discrete-time infinite-dimensional systems. LQG-balanced realizations are those for which the smallest nonnegative self-adjoint solutions of the control and filter Riccati equations are equal. We show 13. Linearization of the Lorenz system Li, Chunbiao; Sprott, Julien Clinton; Thio, Wesley 2015-01-01 A partial and complete piecewise linearized version of the Lorenz system is proposed. The linearized versions have an independent total amplitude control parameter. Additional further linearization leads naturally to a piecewise linear version of the diffusionless Lorenz system. A chaotic circuit with a single amplitude controller is then implemented using a new switch element, producing a chaotic oscillation that agrees with the numerical calculation for the piecewise linear diffusionless Lorenz system. - Highlights: • A partial and complete piecewise linearized version of the Lorenz system are addressed. • The linearized versions have an independent total amplitude control parameter. • A piecewise linear version of the diffusionless Lorenz system is derived by further linearization. • A corresponding chaotic circuit without any multiplier is implemented for the chaotic oscillation 14. Topics in computational linear optimization Hultberg, Tim Helge 2000-01-01 Linear optimization has been an active area of research ever since the pioneering work of G. Dantzig more than 50 years ago. This research has produced a long sequence of practical as well as theoretical improvements of the solution techniques avilable for solving linear optimization problems...... of high quality solvers and the use of algebraic modelling systems to handle the communication between the modeller and the solver. This dissertation features four topics in computational linear optimization: A) automatic reformulation of mixed 0/1 linear programs, B) direct solution of sparse unsymmetric...... systems of linear equations, C) reduction of linear programs and D) integration of algebraic modelling of linear optimization problems in C++. Each of these topics is treated in a separate paper included in this dissertation. The efficiency of solving mixed 0-1 linear programs by linear programming based... 15. Linearization of the Lorenz system Li, Chunbiao, E-mail: goontry@126.com [School of Electronic & Information Engineering, Nanjing University of Information Science & Technology, Nanjing 210044 (China); Engineering Technology Research and Development Center of Jiangsu Circulation Modernization Sensor Network, Jiangsu Institute of Commerce, Nanjing 211168 (China); Sprott, Julien Clinton [Department of Physics, University of Wisconsin–Madison, Madison, WI 53706 (United States); Thio, Wesley [Department of Electrical and Computer Engineering, The Ohio State University, Columbus, OH 43210 (United States) 2015-05-08 A partial and complete piecewise linearized version of the Lorenz system is proposed. The linearized versions have an independent total amplitude control parameter. Additional further linearization leads naturally to a piecewise linear version of the diffusionless Lorenz system. A chaotic circuit with a single amplitude controller is then implemented using a new switch element, producing a chaotic oscillation that agrees with the numerical calculation for the piecewise linear diffusionless Lorenz system. - Highlights: • A partial and complete piecewise linearized version of the Lorenz system are addressed. • The linearized versions have an independent total amplitude control parameter. • A piecewise linear version of the diffusionless Lorenz system is derived by further linearization. • A corresponding chaotic circuit without any multiplier is implemented for the chaotic oscillation. 16. Decomposed Implicit Models of Piecewise - Linear Networks J. Brzobohaty 1992-05-01 Full Text Available The general matrix form of the implicit description of a piecewise-linear (PWL network and the symbolic block diagram of the corresponding circuit model are proposed. Their decomposed forms enable us to determine quite separately the existence of the individual breakpoints of the resultant PWL characteristic and their coordinates using independent network parameters. For the two-diode and three-diode cases all the attainable types of the PWL characteristic are introduced. 17. Emmy Noether and Linear Evolution Equations P. G. L. Leach 2013-01-01 Full Text Available Noether’s Theorem relates the Action Integral of a Lagrangian with symmetries which leave it invariant and the first integrals consequent upon the variational principle and the existence of the symmetries. These each have an equivalent in the Schrödinger Equation corresponding to the Lagrangian and by extension to linear evolution equations in general. The implications of these connections are investigated. 18. Does Glocal Political Power Already Exist? Lorenzo Ornaghi 2017-05-01 Full Text Available Large periods of history are usually characterized by equally important moments of change in scientific knowledge and, in particular, in the understanding of political power. We still need to study in depth whether the former provokes (almost of out necessity the latter, or whether they are “great” because they are favored by the innovation of the paradigms of knowledge. The passage from medieval universalism to the particularism of the modern age represents an extremely interesting analogy when compared to the transformations that are now underway. The example of John of Salisbury’s Policratus, the starting point of this article, is illuminating in our comprehension of the relevance of the interweaving between the persistence of the ancient forms of recognition of power and the search for new forms. The existence of glocal realities is already a fact. Even if it is relatively easy to recognize these realities (a business, a university, a humanitarian association, not a few of the same “parts” which constitute the traditional organization of the State, it is more difficult to define the specific characteristics of the power at their disposal. Moving from the widening gap between “actual” power and “potential” power, the article examines the motives for which the classical definitions of power are always becoming more insufficient in understanding the role now emerging from glocal realities. And, in particular, by looking at how the “command-obedience” relationship is changing also as a consequence of communication networks and information technology, the article analyzes that specific “contamination” within global elements and local elements, which seems to be the main base of glocal political power. 19. Abusive Relationships ... Safe Videos for Educators Search English Español Abusive Relationships KidsHealth / For Teens / Abusive Relationships Print en español Relaciones de maltrato Healthy Relationships = Respect & Trust Healthy relationships involve respect, trust, and ... 20. On the linear programming bound for linear Lee codes. Astola, Helena; Tabus, Ioan 2016-01-01 Based on an invariance-type property of the Lee-compositions of a linear Lee code, additional equality constraints can be introduced to the linear programming problem of linear Lee codes. In this paper, we formulate this property in terms of an action of the multiplicative group of the field [Formula: see text] on the set of Lee-compositions. We show some useful properties of certain sums of Lee-numbers, which are the eigenvalues of the Lee association scheme, appearing in the linear programming problem of linear Lee codes. Using the additional equality constraints, we formulate the linear programming problem of linear Lee codes in a very compact form, leading to a fast execution, which allows to efficiently compute the bounds for large parameter values of the linear codes. 1. Do Elementary Particles Have an Objective Existence? Nissenson, Bilha 2007-01-01 The formulation of quantum theory does not comply with the notion of objective existence of elementary particles. Objective existence independent of observation implies the distinguishability of elementary particles. In other words: If elementary particles have an objective existence independent of observations, then they are distinguishable. Or if elementary particles are indistinguishable then matter cannot have existence independent of our observation. This paper presents a simple deductio... 2. 34 CFR 104.22 - Existing facilities. 2010-07-01 ... 34 Education 1 2010-07-01 2010-07-01 false Existing facilities. 104.22 Section 104.22 Education... Accessibility § 104.22 Existing facilities. (a) Accessibility. A recipient shall operate its program or activity.... This paragraph does not require a recipient to make each of its existing facilities or every part of a... 3. 45 CFR 1170.32 - Existing facilities. 2010-10-01 ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Existing facilities. 1170.32 Section 1170.32... ASSISTED PROGRAMS OR ACTIVITIES Accessibility § 1170.32 Existing facilities. (a) Accessibility. A recipient... require a recipient to make each of its existing facilities or every part of a facility accessible to and... 4. 45 CFR 605.22 - Existing facilities. 2010-10-01 ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Existing facilities. 605.22 Section 605.22 Public... Accessibility § 605.22 Existing facilities. (a) Accessibility. A recipient shall operate each program or... existing facilities or every part of a facility accessible to and usable by qualified handicapped persons... 5. 14 CFR 1251.301 - Existing facilities. 2010-01-01 ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Existing facilities. 1251.301 Section 1251... HANDICAP Accessibility § 1251.301 Existing facilities. (a) Accessibility. A recipient shall operate each... existing facilities or every part of a facility accessible to and usable by handicapped persons. (b... 6. 45 CFR 1151.22 - Existing facilities. 2010-10-01 ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Existing facilities. 1151.22 Section 1151.22... Prohibited Accessibility § 1151.22 Existing facilities. (a) A recipient shall operate each program or... make each of its existing facilities or every part of a facility accessible to and usable by... 7. 10 CFR 611.206 - Existing facilities. 2010-01-01 ... 10 Energy 4 2010-01-01 2010-01-01 false Existing facilities. 611.206 Section 611.206 Energy... PROGRAM Facility/Funding Awards § 611.206 Existing facilities. The Secretary shall, in making awards to those manufacturers that have existing facilities, give priority to those facilities that are oldest or... 8. Introduction to linear elasticity Gould, Phillip L 2013-01-01 Introduction to Linear Elasticity, 3rd Edition, provides an applications-oriented grounding in the tensor-based theory of elasticity for students in mechanical, civil, aeronautical, and biomedical engineering, as well as materials and earth science. The book is distinct from the traditional text aimed at graduate students in solid mechanics by introducing the subject at a level appropriate for advanced undergraduate and beginning graduate students. The author's presentation allows students to apply the basic notions of stress analysis and move on to advanced work in continuum mechanics, plasticity, plate and shell theory, composite materials, viscoelasticity and finite method analysis. This book also: Emphasizes tensor-based approach while still distilling down to explicit notation Provides introduction to theory of plates, theory of shells, wave propagation, viscoelasticity and plasticity accessible to advanced undergraduate students Appropriate for courses following emerging trend of teaching solid mechan... 9. Linear step drive Haniger, L.; Elger, R.; Kocandrle, L.; Zdebor, J. 1986-01-01 A linear step drive is described developed in Czechoslovak-Soviet cooperation and intended for driving WWER-1000 control rods. The functional principle is explained of the motor and the mechanical and electrical parts of the drive, power control, and the indicator of position are described. The motor has latches situated in the reactor at a distance of 3 m from magnetic armatures, it has a low structural height above the reactor cover, which suggests its suitability for seismic localities. Its magnetic circuits use counterpoles; the mechanical shocks at the completion of each step are damped using special design features. The position indicator is of a special design and evaluates motor position within ±1% of total travel. A drive diagram and the flow chart of both the control electronics and the position indicator are presented. (author) 4 figs 10. Linear pulse amplifier Tjutju, R.L. 1977-01-01 Pulse amplifier is standard significant part of spectrometer. Apart from other type of amplification, it's a combination of amplification and pulse shaping. Because of its special purpose the device should fulfill the following : High resolution is desired to gain a high yield comparable to its actual state of condition. High signal to noise is desired to nhν resolution. High linearity to facilitate calibration. A good overload recovery, in order to the device will capable of analizing a low energy radiation which appear joinly on the high energy fields. Other expections of the device are its economical and practical use its extentive application. For that reason it's built on a standard NIM principle. Taking also into account the above mentioned considerations. High quality component parts are used throughout, while its availability in the domestic market is secured. (author) 11. Linear Accelerator Laboratory 1976-01-01 This report covers the activity of the Linear Accelerator Laboratory during the period June 1974-June 1976. The activity of the Laboratory is essentially centered on high energy physics. The main activities were: experiments performed with the colliding rings (ACO), construction of the new colliding rings and beginning of the work at higher energy (DCI), bubble chamber experiments with the CERN PS neutrino beam, counter experiments with CERN's PS and setting-up of equipment for new experiments with CERN's SPS. During this period a project has also been prepared for an experiment with the new PETRA colliding ring at Hamburg. On the other hand, intense collaboration with the LURE Laboratory, using the electron synchrotron radiation emitted by ACO and DCI, has been developed [fr 12. HEAVY ION LINEAR ACCELERATOR Van Atta, C.M.; Beringer, R.; Smith, L. 1959-01-01 A linear accelerator of heavy ions is described. The basic contributions of the invention consist of a method and apparatus for obtaining high energy particles of an element with an increased charge-to-mass ratio. The method comprises the steps of ionizing the atoms of an element, accelerating the resultant ions to an energy substantially equal to one Mev per nucleon, stripping orbital electrons from the accelerated ions by passing the ions through a curtain of elemental vapor disposed transversely of the path of the ions to provide a second charge-to-mass ratio, and finally accelerating the resultant stripped ions to a final energy of at least ten Mev per nucleon. 13. Linear absorptive dielectrics Tip, A. 1998-06-01 Starting from Maxwell's equations for a linear, nonconducting, absorptive, and dispersive medium, characterized by the constitutive equations D(x,t)=ɛ1(x)E(x,t)+∫t-∞dsχ(x,t-s)E(x,s) and H(x,t)=B(x,t), a unitary time evolution and canonical formalism is obtained. Given the complex, coordinate, and frequency-dependent, electric permeability ɛ(x,ω), no further assumptions are made. The procedure leads to a proper definition of band gaps in the periodic case and a new continuity equation for energy flow. An S-matrix formalism for scattering from lossy objects is presented in full detail. A quantized version of the formalism is derived and applied to the generation of Čerenkov and transition radiation as well as atomic decay. The last case suggests a useful generalization of the density of states to the absorptive situation. 14. [Does the right to die with dignity exist?]. Toro Flores, Rafael 2008-12-01 Death is one of the few certainties in human beings. This reality generates uneasiness regarding how death will occur especially in circumstances of loneliness or suffering which can become agony. In this report, the author first analyzes the existence of the right to die with dignity as a human right which takes on the nature of being a subjective right. In continuation, the author describes the existing problematic in the application of this right to die in relationship to the so-called double effect mechanism and euthanasia. The author concludes this article by proposing previous instructions or anticipated desires as ideal measures to make the right to die with dignity valid. 15. Computer Program For Linear Algebra Krogh, F. T.; Hanson, R. J. 1987-01-01 Collection of routines provided for basic vector operations. Basic Linear Algebra Subprogram (BLAS) library is collection from FORTRAN-callable routines for employing standard techniques to perform basic operations of numerical linear algebra. 16. Quaternion Linear Canonical Transform Application Bahri, Mawardi 2015-01-01 Quaternion linear canonical transform (QLCT) is a generalization of the classical linear canonical transfom (LCT) using quaternion algebra. The focus of this paper is to introduce an application of the QLCT to study of generalized swept-frequency filter 17. Recursive Algorithm For Linear Regression Varanasi, S. V. 1988-01-01 Order of model determined easily. Linear-regression algorithhm includes recursive equations for coefficients of model of increased order. Algorithm eliminates duplicative calculations, facilitates search for minimum order of linear-regression model fitting set of data satisfactory. 18. Dynamical systems and linear algebra Colonius, Fritz (Prof.) 2007-01-01 Dynamical systems and linear algebra / F. Colonius, W. Kliemann. - In: Handbook of linear algebra / ed. by Leslie Hogben. - Boca Raton : Chapman & Hall/CRC, 2007. - S. 56,1-56,22. - (Discrete mathematics and its applications) 19. Linear spaces: history and theory Albrecht Beutelspracher 1990-01-01 Linear spaces belong to the most fundamental geometric and combinatorial structures. In this paper I would like to give an onerview about the theory of embedding finite linear spaces in finite projective planes. 20. Linear versus non-linear supersymmetry, in general Ferrara, Sergio [Theoretical Physics Department, CERN,CH-1211 Geneva 23 (Switzerland); INFN - Laboratori Nazionali di Frascati,Via Enrico Fermi 40, I-00044 Frascati (Italy); Department of Physics and Astronomy, UniversityC.L.A.,Los Angeles, CA 90095-1547 (United States); Kallosh, Renata [SITP and Department of Physics, Stanford University,Stanford, California 94305 (United States); Proeyen, Antoine Van [Institute for Theoretical Physics, Katholieke Universiteit Leuven,Celestijnenlaan 200D, B-3001 Leuven (Belgium); Wrase, Timm [Institute for Theoretical Physics, Technische Universität Wien,Wiedner Hauptstr. 8-10, A-1040 Vienna (Austria) 2016-04-12 We study superconformal and supergravity models with constrained superfields. The underlying version of such models with all unconstrained superfields and linearly realized supersymmetry is presented here, in addition to the physical multiplets there are Lagrange multiplier (LM) superfields. Once the equations of motion for the LM superfields are solved, some of the physical superfields become constrained. The linear supersymmetry of the original models becomes non-linearly realized, its exact form can be deduced from the original linear supersymmetry. Known examples of constrained superfields are shown to require the following LM’s: chiral superfields, linear superfields, general complex superfields, some of them are multiplets with a spin. 1. Linear versus non-linear supersymmetry, in general Ferrara, Sergio; Kallosh, Renata; Proeyen, Antoine Van; Wrase, Timm 2016-01-01 We study superconformal and supergravity models with constrained superfields. The underlying version of such models with all unconstrained superfields and linearly realized supersymmetry is presented here, in addition to the physical multiplets there are Lagrange multiplier (LM) superfields. Once the equations of motion for the LM superfields are solved, some of the physical superfields become constrained. The linear supersymmetry of the original models becomes non-linearly realized, its exact form can be deduced from the original linear supersymmetry. Known examples of constrained superfields are shown to require the following LM’s: chiral superfields, linear superfields, general complex superfields, some of them are multiplets with a spin. 2. Linear free energy relationship in reactions between diphenyl amine ... Unknown Frost A A and Pearson R G 1970 Kinetics and mechanism 2nd edn (New Delhi: Wiley Eastern) p. 37. 9. Nakanishi K and Solomon P H 1977 Infrared absorp- tion spectroscopy (Holden Day) p. 50. 10. Hammett L P 1935 Chem. Rev. 17 125. 11. Shorter J 1973 Correlation analysis in organic che- mistry (Oxford: Clarendon). 3. Linking GeoGebra to Explorations of Linear Relationships Aventi, Belinda; Serow, Penelope; Tobias, Steve 2014-01-01 Increasing pressure is mounting from all areas of society to maximise technology use within educational domains. Whilst curriculum documents call for the utilisation of technology as a teaching tool in the mathematics classroom, the benefits of exploring forms of dynamic mathematical software, such as GeoGebra, are often introduced in the senior… 4. Cultural distance and international trade: a non-linear relationship Lankhuizen, M.B.M.; de Groot, H.L.F. 2016-01-01 This paper investigates the effect of culture on trade using measures of cultural distance based on various dimensions of national culture from Hofstede (Culture’s Consequences: International Differences in Work-Related Values, 1980; Culture’s Consequences: Comparing Values, Behaviors, Institutions 5. A primer on linear models Monahan, John F 2008-01-01 Preface Examples of the General Linear Model Introduction One-Sample Problem Simple Linear Regression Multiple Regression One-Way ANOVA First Discussion The Two-Way Nested Model Two-Way Crossed Model Analysis of Covariance Autoregression Discussion The Linear Least Squares Problem The Normal Equations The Geometry of Least Squares Reparameterization Gram-Schmidt Orthonormalization Estimability and Least Squares Estimators Assumptions for the Linear Mean Model Confounding, Identifiability, and Estimability Estimability and Least Squares Estimators F 6. An inhomogeneous wave equation and non-linear Diophantine approximation Beresnevich, V.; Dodson, M. M.; Kristensen, S. 2008-01-01 A non-linear Diophantine condition involving perfect squares and arising from an inhomogeneous wave equation on the torus guarantees the existence of a smooth solution. The exceptional set associated with the failure of the Diophantine condition and hence of the existence of a smooth solution... 7. Templates for Linear Algebra Problems Bai, Z.; Day, D.; Demmel, J.; Dongarra, J.; Gu, M.; Ruhe, A.; Vorst, H.A. van der 1995-01-01 The increasing availability of advanced-architecture computers is having a very signicant eect on all spheres of scientic computation, including algorithm research and software development in numerical linear algebra. Linear algebra {in particular, the solution of linear systems of equations and 8. Linearization of CIF through SOS Nadales Agut, D.E.; Reniers, M.A.; Luttik, B.; Valencia, F. 2011-01-01 Linearization is the procedure of rewriting a process term into a linear form, which consist only of basic operators of the process language. This procedure is interesting both from a theoretical and a practical point of view. In particular, a linearization algorithm is needed for the Compositional 9. Linear Logic on Petri Nets Engberg, Uffe Henrik; Winskel, Glynn This article shows how individual Petri nets form models of Girard's intuitionistic linear logic. It explores questions of expressiveness and completeness of linear logic with respect to this interpretation. An aim is to use Petri nets to give an understanding of linear logic and give some apprai... 10. Atomic core-ionization energies; approximately piecewise-linear and linear relationships Avery, James Emil; Avery, John Scales 2008-01-01 as to make all of the members of the basis set correspond to the energy of the state being represented. In this paper we apply the method to core ionization in atoms and atomic ions, using a basis where\\op{V}_0(\\xx)\$ is chosen   to be the nuclear attraction potential. We make use of a large...

11. Linear particle accelerator

Richards, J.A.

1977-01-01

A linear particle accelerator which provides a pulsed beam of charged particles of uniform energy is described. The accelerator is in the form of an evacuated dielectric tube, inside of which a particle source is located at one end of the tube, with a target or window located at the other end of the dielectric tube. Along the length of the tube are externally located pairs of metal plates, each insulated from each other in an insulated housing. Each of the plates of a pair are connected to an electrical source of voltage of opposed polarity, with the polarity of the voltage of the plates oriented so that the plate of a pair, nearer to the particle source, is of the opposed polarity to the charge of the particle emitted by the source. Thus, a first plate about the tube located nearest the particle source, attracts a particle which as it passes through the tube past the first plate is then repelled by the reverse polarity of the second plate of the pair to continue moving towards the target

12. Generalized Linear Covariance Analysis

Carpenter, James R.; Markley, F. Landis

2014-01-01

This talk presents a comprehensive approach to filter modeling for generalized covariance analysis of both batch least-squares and sequential estimators. We review and extend in two directions the results of prior work that allowed for partitioning of the state space into solve-for'' and consider'' parameters, accounted for differences between the formal values and the true values of the measurement noise, process noise, and textita priori solve-for and consider covariances, and explicitly partitioned the errors into subspaces containing only the influence of the measurement noise, process noise, and solve-for and consider covariances. In this work, we explicitly add sensitivity analysis to this prior work, and relax an implicit assumption that the batch estimator's epoch time occurs prior to the definitive span. We also apply the method to an integrated orbit and attitude problem, in which gyro and accelerometer errors, though not estimated, influence the orbit determination performance. We illustrate our results using two graphical presentations, which we call the variance sandpile'' and the sensitivity mosaic,'' and we compare the linear covariance results to confidence intervals associated with ensemble statistics from a Monte Carlo analysis.

13. Equipartitioning in linear accelerators

Jameson, R.A.

1982-01-01

Emittance growth has long been a concern in linear accelerators, as has the idea that some kind of energy balance, or equipartitioning, between the degrees of freedom, would ameliorate the growth. M. Prome observed that the average transverse and longitudinal velocity spreads tend to equalize as current in the channel is increased, while the sum of the energy in the system stays nearly constant. However, only recently have we shown that an equipartitioning requirement on a bunched injected beam can indeed produce remarkably small emittance growth. The simple set of equations leading to this condition are outlined. At the same time, Hofmann has investigated collective instabilities in transported beams and has identified thresholds and regions in parameter space where instabilities occur. Evidence is presented that shows transport system boundaries to be quite accurate in computer simulations of accelerating systems. Discussed are preliminary results of efforts to design accelerators that avoid parameter regions where emittance is affected by the instabilities identified by Hofmann. These efforts suggest that other mechanisms are present. The complicated behavior of the RFQ linac in this framework also is shown

14. Equipartitioning in linear accelerators

Jameson, R.A.

1981-01-01

Emittance growth has long been a concern in linear accelerators, as has the idea that some kind of energy balance, or equipartitioning, between the degrees of freedom, would ameliorate the growth. M. Prome observed that the average transverse and longitudinal velocity spreads tend to equalize as current in the channel is increased, while the sum of the energy in the system stays nearly constant. However, only recently have we shown that an equipartitioning requirement on a bunched injected beam can indeed produce remarkably small emittance growth. The simple set of equations leading to this condition are outlined below. At the same time, Hofmann, using powerful analytical and computational methods, has investigated collective instabilities in transported beams and has identified thresholds and regions in parameter space where instabilities occur. This is an important generalization. Work that he will present at this conference shows that the results are essentially the same in r-z coordinates for transport systems, and evidence is presented that shows transport system boundaries to be quite accurate in computer simulations of accelerating systems also. Discussed are preliminary results of efforts to design accelerators that avoid parameter regions where emittance is affected by the instabilities identified by Hofmann. These efforts suggest that other mechanisms are present. The complicated behavior of the RFQ linac in this framework also is shown

15. Berkeley Proton Linear Accelerator

Alvarez, L. W.; Bradner, H.; Franck, J.; Gordon, H.; Gow, J. D.; Marshall, L. C.; Oppenheimer, F. F.; Panofsky, W. K. H.; Richman, C.; Woodyard, J. R.

1953-10-13

A linear accelerator, which increases the energy of protons from a 4 Mev Van de Graaff injector, to a final energy of 31.5 Mev, has been constructed. The accelerator consists of a cavity 40 feet long and 39 inches in diameter, excited at resonance in a longitudinal electric mode with a radio-frequency power of about 2.2 x 10{sup 6} watts peak at 202.5 mc. Acceleration is made possible by the introduction of 46 axial "drift tubes" into the cavity, which is designed such that the particles traverse the distance between the centers of successive tubes in one cycle of the r.f. power. The protons are longitudinally stable as in the synchrotron, and are stabilized transversely by the action of converging fields produced by focusing grids. The electrical cavity is constructed like an inverted airplane fuselage and is supported in a vacuum tank. Power is supplied by 9 high powered oscillators fed from a pulse generator of the artificial transmission line type.

16. Existence of optimal controls for systems governed by mean-field ...

In this paper, we study the existence of an optimal control for systems, governed by stochastic dierential equations of mean-eld type. For non linear systems, we prove the existence of an optimal relaxed control, by using tightness techniques and Skorokhod selection theorem. The optimal control is a measure valued process ...

17. Non-linear Q-clouds around Kerr black holes

2014-01-01

Q-balls are regular extended ‘objects’ that exist for some non-gravitating, self-interacting, scalar field theories with a global, continuous, internal symmetry, on Minkowski spacetime. Here, analogous objects are also shown to exist around rotating (Kerr) black holes, as non-linear bound states of a test scalar field. We dub such configurations Q-clouds. We focus on a complex massive scalar field with quartic plus hexic self-interactions. Without the self-interactions, linear clouds have been shown to exist, in synchronous rotation with the black hole horizon, along 1-dimensional subspaces – existence lines – of the Kerr 2-dimensional parameter space. They are zero modes of the superradiant instability. Non-linear Q-clouds, on the other hand, are also in synchronous rotation with the black hole horizon; but they exist on a 2-dimensional subspace, delimited by a minimal horizon angular velocity and by an appropriate existence line, wherein the non-linear terms become irrelevant and the Q-cloud reduces to a linear cloud. Thus, Q-clouds provide an example of scalar bound states around Kerr black holes which, generically, are not zero modes of the superradiant instability. We describe some physical properties of Q-clouds, whose backreaction leads to a new family of hairy black holes, continuously connected to the Kerr family

18. Solving fault diagnosis problems linear synthesis techniques

Varga, Andreas

2017-01-01

This book addresses fault detection and isolation topics from a computational perspective. Unlike most existing literature, it bridges the gap between the existing well-developed theoretical results and the realm of reliable computational synthesis procedures. The model-based approach to fault detection and diagnosis has been the subject of ongoing research for the past few decades. While the theoretical aspects of fault diagnosis on the basis of linear models are well understood, most of the computational methods proposed for the synthesis of fault detection and isolation filters are not satisfactory from a numerical standpoint. Several features make this book unique in the fault detection literature: Solution of standard synthesis problems in the most general setting, for both continuous- and discrete-time systems, regardless of whether they are proper or not; consequently, the proposed synthesis procedures can solve a specific problem whenever a solution exists Emphasis on the best numerical algorithms to ...

19. Random linear codes in steganography

Kamil Kaczyński

2016-12-01

Full Text Available Syndrome coding using linear codes is a technique that allows improvement in the steganographic algorithms parameters. The use of random linear codes gives a great flexibility in choosing the parameters of the linear code. In parallel, it offers easy generation of parity check matrix. In this paper, the modification of LSB algorithm is presented. A random linear code [8, 2] was used as a base for algorithm modification. The implementation of the proposed algorithm, along with practical evaluation of algorithms’ parameters based on the test images was made.[b]Keywords:[/b] steganography, random linear codes, RLC, LSB

20. Sharing information among existing data sources

Ashley, W. R., III

1999-01-01

The sharing of information between law enforcement agencies is a premise for the success of all jurisdictions. A wealth of information resides in both the databases and infrastructures of local, state, and regional agencies. However, this information is often not available to the law enforcement professionals who require it. When the information is, available, individual investigators must not only know that it exists, but where it resides, and how to retrieve it. In many cases, these types of cross-jurisdictional communications are limited to personal relationships that result from telephone calls, faxes, and in some cases, e-mail. As criminal elements become more sophisticated and distributed, law enforcement agencies must begin to develop infrastructures and common sharing mechanisms that address a constantly evolving criminal threat. Historically, criminals have taken advantage of the lack of communication between law enforcement agencies. Examples of this are evident in the search for stolen property and monetary dealings. Pawned property, cash transactions, and failure to supply child support are three common cross- jurisdictional crimes that could be better enforced by strengthening the lines of communication. Criminal behavior demonstrates that it is easier to profit from their actions by dealing in separate jurisdictions. For example, stolen property is sold outside of the jurisdiction of its origin. In most cases, simply traveling a short distance to the adjoining county or municipality is sufficient to ensure that apprehension of the criminal or seizure of the stolen property is highly unlikely. In addition to the traditional burglar, fugitives often sell or pawn property to finance their continued evasion from the law. Sharing of information in a rapid manner would increase the ability of law enforcement personnel to track and capture fugitives, as well as criminals. In an example to combat this threat, the State of Florida recently acted on the need to