WorldWideScience

Sample records for line capacity planning

  1. Capacity planning and management

    Boydell, Briony

    2011-01-01

    After reading this chapter you should be able to: • Define and measure capacity and appreciate the factors that influence it. • Assess the difficulties of matching capacity to demand. • Evaluate and apply the different strategies for matching capacity with demand in the short, medium and long term. • Analyse the impact of constraints and bottlenecks on a process and consider the Theory of Constraints. • Outline the different strategies available for both manufacturing and service operations. ...

  2. Capacity Planning and Leadtime management

    Zijm, Willem H.M.; Buitenhek, R.

    1996-01-01

    In this paper we discuss a framework for capacity planning and lead time management in manufacturing companies, with an emphasis on the machine shop. First we show how queueing models can be used to find approximations of the mean and the variance of manufacturing shop lead times. These quantities

  3. Integrating robust timetabling in line plan optimization for railway systems

    Burggraeve, Sofie; Bull, Simon Henry; Vansteenwegen, Pieter

    2017-01-01

    We propose a heuristic algorithm to build a railway line plan from scratch that minimizes passenger travel time and operator cost and for which a feasible and robust timetable exists. A line planning module and a timetabling module work iteratively and interactively. The line planning module......, but is constrained by limited shunt capacity. While the operator and passenger cost remain close to those of the initially and (for these costs) optimally built line plan, the timetable corresponding to the finally developed robust line plan significantly improves the minimum buffer time, and thus the robustness...... creates an initial line plan. The timetabling module evaluates the line plan and identifies a critical line based on minimum buffer times between train pairs. The line planning module proposes a new line plan in which the time length of the critical line is modified in order to provide more flexibility...

  4. Research, Calculation for Designing the Technological Equipment Line of Cementation with 3,000 Tonnes of Solid Waste/Year Capacity for ZOC Plan

    Tran Van Hoa; Ngo Van Tuyen; Nguyen Ba Tien; Le Ba Thuan; Phung Quoc Khanh; Mai Duc Lanh; Vuong Huu Anh; Luu Cao Nguyen; Duong Dinh Tho; Phung Vu Phong; Nguyen An Thai; Pham Quang Minh

    2013-01-01

    Technological process and equipment line for cementation with 3,000 tons of solid wastes/year capacity for ZOC plant was studied according to the quantity, the composition and the property of solid wastes from ZOC plant. The influence of several parameters with cementation process such as cement mixing ratio, size, moisture and NaCl content in residue, which affected to mechanical and chemical strength of waste block after cementation was evaluated. The calculation and designing for cementation equipment line were thus conducted and total investment cost of construction and installation as well as operation of this equipment line was also estimated. Radiation safety and environmental protection for waste treatment facility was calculated and the design on radiation safety and environmental protection for equipment line was proposed. Technological process and design document of this production line seemed to be reasonable because it is consistent with properties of wastes as well as it has been commonly used in the world to stabilize solid residues in nuclear industry. The advantages of this propose were simple structure of the devices, locally made, easy operation, locally available and inexpensive materials resulting in low cost of investment and operation. (author)

  5. Russians and Ukrainians plan new gas line

    TREND

    2003-01-01

    Paper deals with the building of new gas line between Russia and the Ukraine. In September 2003 Gazprom and Naftohaz Ukraine signed protocol about conditions of Russian gas transit through Ukrainian area for 2004. There is guaranteed quantity of transported gas on the level of 127,8 billions cubic meters by Russian side, 110 billions of it should next lead to Europe. Treaty refills long-term contract between Naftohaz and Gazprom about gas transit through Ukraine for period 2003-2013. Both countries and its companies plan to accept particular capital decision about building of new gas line Novopskov-Uzgorod till end of this year, which will be parallel with gas line Soyuz. It will allow to enlarge transportation system capacity by 28 billion cubic meters. Construction of about 1600 km long ducting system will require 1.6 billion USD by annual capacity about 15 billion cubic meters. If capacity would be doubled by construction of another compressor stations, capital expenses rise to 2.2 billions USD. It can be completely built in 7 years. Its linear part with one compressor can be already built in 3 years. Slovensky Plynarensky Podnik (SPP) would certainly have advantages from possible realisation of new gas line and from consequential transit increase. (Author)

  6. Pdvsa plans to hike productive capacity

    Anon.

    1992-01-01

    This paper reports that Venezuela's state oil company plans to jump its productive capacity by 117,000 b/d to 2.92 million b/d this year. Petroleos de Venezuela also projects sizable increases for oil and gas reserves and plans record spending in 1992. Meantime, Pdvsa is sounding a warning again about the Venezuelan government's excessive tax take amid debate within the company about spending priorities

  7. Generation capacity expansion planning in deregulated electricity markets

    Sharma, Deepak

    With increasing demand of electric power in the context of deregulated electricity markets, a good strategic planning for the growth of the power system is critical for our tomorrow. There is a need to build new resources in the form of generation plants and transmission lines while considering the effects of these new resources on power system operations, market economics and the long-term dynamics of the economy. In deregulation, the exercise of generation planning has undergone a paradigm shift. The first stage of generation planning is now undertaken by the individual investors. These investors see investments in generation capacity as an increasing business opportunity because of the increasing market prices. Therefore, the main objective of such a planning exercise, carried out by individual investors, is typically that of long-term profit maximization. This thesis presents some modeling frameworks for generation capacity expansion planning applicable to independent investor firms in the context of power industry deregulation. These modeling frameworks include various technical and financing issues within the process of power system planning. The proposed modeling frameworks consider the long-term decision making process of investor firms, the discrete nature of generation capacity addition and incorporates transmission network modeling. Studies have been carried out to examine the impact of the optimal investment plans on transmission network loadings in the long-run by integrating the generation capacity expansion planning framework within a modified IEEE 30-bus transmission system network. The work assesses the importance of arriving at an optimal IRR at which the firm's profit maximization objective attains an extremum value. The mathematical model is further improved to incorporate binary variables while considering discrete unit sizes, and subsequently to include the detailed transmission network representation. The proposed models are novel in the

  8. Integrating robust timetabling in line plan optimization for railway systems

    Burggraeve, Sofie; Bull, Simon Henry; Lusby, Richard Martin

    The line planning problem in rail is to select a number of lines froma potential pool which provides sufficient passenger capacity and meetsoperational requirements, with some objective measure of solution linequality. We model the problem of minimizing the average passenger systemtime, including...... frequency-dependent estimates for switching between lines,working with the Danish rail operator DSB and data for Copenhagen commuters.We present a multi-commodity flow formulation for the problemof freely routing passengers, coupled to discrete line-frequency decisionsselecting lines from a predefined pool...

  9. Linear-programming-based heuristics for project capacity planning

    Gademann, A.J.R.M.; Schutten, J.M.J.

    2005-01-01

    Many multi-project organizations are capacity driven, which means that their operations are constrained by various scarce resources. An important planning aspect in a capacity driven multi-project organization is capacity planning. By capacity planning, we mean the problem of matching demand for

  10. Effect of Different Structure Type Traffic On Railway Line Capacity

    Gleba Radosław

    2017-04-01

    Full Text Available The article points to methods of analyzing railway traffic conditions based on two parameters: capacity and delay of trains. The impact of the differentiated railway type structure on the capacity of the railway line was presented. Particular attention has been paid to the assessment of commonly used simplifications in analyzes.

  11. Incentive-Compatible Robust Line Planning

    Bessas, Apostolos; Kontogiannis, Spyros; Zaroliagis, Christos

    The problem of robust line planning requests for a set of origin-destination paths (lines) along with their frequencies in an underlying railway network infrastructure, which are robust to fluctuations of real-time parameters of the solution. In this work, we investigate a variant of robust line planning stemming from recent regulations in the railway sector that introduce competition and free railway markets, and set up a new application scenario: there is a (potentially large) number of line operators that have their lines fixed and operate as competing entities issuing frequency requests, while the management of the infrastructure itself remains the responsibility of a single entity, the network operator. The line operators are typically unwilling to reveal their true incentives, while the network operator strives to ensure a fair (or socially optimal) usage of the infrastructure, e.g., by maximizing the (unknown to him) aggregate incentives of the line operators.

  12. Fuzzy multi-project rough-cut capacity planning

    Masmoudi, Malek; Hans, Elias W.; Leus, Roel; Hait, Alain; Sotskov, Yuri N.; Werner, Frank

    2014-01-01

    This chapter studies the incorporation of uncertainty into multi-project rough-cut capacity planning. We use fuzzy sets to model uncertainties, adhering to the so-called possibilistic approach. We refer to the resulting proactive planning environment as Fuzzy Rough Cut Capacity Planning (FRCCP).

  13. An optimization based method for line planning to minimize travel time

    Bull, Simon Henry; Lusby, Richard Martin; Larsen, Jesper

    2015-01-01

    The line planning problem is to select a number of lines from a potential pool which provides sufficient passenger capacity and meets operational requirements, with some objective measure of solution line quality. We model the problem of minimizing the average passenger system time, including...

  14. Train turn restrictions and line plan performance

    Burggraeve, Sofie; Bull, Simon Henry; Lusby, Richard Martin

    In this paper we study the impact of the `turn conditions' in end stations on the performance of a line plan. If trains have to turn on their platform in an end station, the yoccupy the platform for several minutes. A more preferred option, from a timetabling point of view, would be that a train...... in a exible and large enough shunt. Starting from a given line plan, we compare two timetables, one where trains have to turn on their platform and one where trains can turn in a shunt. We evaluate the impact on the performance of the line plan by its feasibility for timetabling,the minimum overall buffer...... disappears from the platform in its end station after dwelling and only appears again when departing for a subsequent trip. In this case, the train will not interfere with other trains that dwell on the platform during the time between these events. However, this option is only possible if the train can stay...

  15. Strategic service-line planning. Building competitive advantage.

    Greenspan, Elizabeth; Krentz, Susanna E; O'Neill, Molly K

    2003-12-01

    Service-line planning requires a healthcare organization to develop a business plan for each of its service lines. Successful service-line planning requires top leadership support, a willingness to allocate resources, the development of support mechanisms, the active support and involvement of physicians, and management commitment and accountability during implementation.

  16. An applied optimization based method for line planning to minimize travel time

    Bull, Simon Henry; Rezanova, Natalia Jurjevna; Lusby, Richard Martin

    The line planning problem in rail is to select a number of lines froma potential pool which provides sufficient passenger capacity and meetsoperational requirements, with some objective measure of solution linequality. We model the problem of minimizing the average passenger systemtime, including...

  17. Study of Parameters that Determine Railway Line Capacity

    Josip Kukec

    2005-07-01

    Full Text Available In this work the study focuses on:- determining the elements required to determine the locationfor the installation of the main signals,- calculated block lengths, and- calculations of optimal head ways, that have not been studiedin detail although they deserve special attention due totheir impact.Generally speaking, the signals are installed in compliancewith the local circumstances, i. e. according to the technicaland technological characteristics and conditions determinedby the traffic places of work they protect.The distribution and length of the blocks depend on: therailway line and its exploitation characteristics, structure andtype of trains that run on the railway line, traffic organisationand signalisation system, as well as technical and exploitationcharacte1istics of the traction vehicles and the rolling stock.What has to be considered is that the minimum section lengthcannot be shorter than the length of the braking distance, i. e.the length of the longest train which runs on the respective railwayline.The study of these parameters is supplemented by the calculationof the reduction in throughput capacity depending on thelack of uniformity in the operation of trains, which, in order tomaintain the design quality of the transportation se1vice, and inthe activities of establishing and implementing the business policyshouldn't be left out nor bypassed.

  18. Planning for partnerships: Maximizing surge capacity resources through service learning.

    Adams, Lavonne M; Reams, Paula K; Canclini, Sharon B

    2015-01-01

    Infectious disease outbreaks and natural or human-caused disasters can strain the community's surge capacity through sudden demand on healthcare activities. Collaborative partnerships between communities and schools of nursing have the potential to maximize resource availability to meet community needs following a disaster. This article explores how communities can work with schools of nursing to enhance surge capacity through systems thinking, integrated planning, and cooperative efforts.

  19. Improving resource capacity planning in hospitals with business approaches.

    van Lent, Wineke Agnes Marieke; van Lent, W.A.M.

    2011-01-01

    This dissertation contributed to the knowledge on the translation of approaches from businesses and services to improve the resource capacity planning on tactical and operational level in (oncologic) hospital care. The following studies were presented: * Chapter 2 surveyed the business approaches

  20. A Decision Support System for Ship Maintenance Capacity Planning

    de Boer, R.; Schutten, Johannes M.J.; Zijm, Willem H.M.

    1997-01-01

    In this paper, the basic framework and algorithms of a decision support system are discussed, which enhance process and capacity planning at a large repair shop. The research is strongly motivated by experiences in a project carried out at a dockyard, which performs repair, overhaul and modification

  1. Building capacity for energy and electricity planning for sustainable development

    2008-09-01

    The IAEA, through its Planning and Economic Studies Section (PESS), assists Member States to build their capacities to perform analyses for developing alternative strategies for sustainable energy development, evaluate the energy-economic-environmental implications and assess the potential contribution of nuclear energy in securing affordable and clean supplies of energy

  2. Pricing and Capacity Planning Problems in Energy Transmission Networks

    Villumsen, Jonas Christoffer

    strategy. In the Nordic electricity system a market with zonal prices is adopted. We consider the problem of designing zones in an optimal way explicitly considering uncertainty. Finally, we formulate the integrated problem of pipeline capacity expansion planning and transmission pricing in natural gas...... necessitates a radical change in the way we plan and operate energy systems. Another paradigm change which began in the 1990’s for electricity systems is that of deregulation. This has led to a variety of different market structures implemented across the world. In this thesis we discuss capacity planning...... and transmission pricing problems in energy transmission networks. Although the modelling framework applies to energy networks in general, most of the applications discussed concern the transmission of electricity. A number of the problems presented involves transmission switching, which allows the operator...

  3. Electric generating capacity planning: A nonlinear programming approach

    Yakin, M.Z.; McFarland, J.W.

    1987-02-01

    This paper presents a nonlinear programming approach for long-range generating capacity expansion planning in electrical power systems. The objective in the model is the minimization of total cost consisting of investment cost plus generation cost for a multi-year planning horizon. Reliability constraints are imposed by using standard and practical reserve margin requirements. State equations representing the dynamic aspect of the problem are included. The electricity demand (load) and plant availabilities are treated as random variables, and the method of cumulants is used to calculate the expected energy generated by each plant in each year of the planning horizon. The resulting model has a (highly) nonlinear objective function and linear constraints. The planning model is solved over the multiyear planning horizon instead of decomposing it into one-year period problems. This approach helps the utility decision maker to carry out extensive sensitivity analysis easily. A case study example is provided using EPRI test data. Relationships among the reserve margin, total cost and surplus energy generating capacity over the planning horizon are explored by analyzing the model.

  4. Power generation capacity planning under budget constraint in developing countries

    Afful-Dadzie, Anthony; Afful-Dadzie, Eric; Awudu, Iddrisu; Banuro, Joseph Kwaku

    2017-01-01

    Highlights: • A long term stochastic GEP model with budget constraint is developed. • Model suitable for analyzing GEP problems in developing countries. • Model determines optimal mix, size and timing of future generation capacity needs. • A real case study of the Ghana GEP problem was employed. • Insufficient budget leads to costly generation capacity expansion plans. - Abstract: This paper presents a novel multi-period stochastic optimization model for studying long-term power generation capacity planning in developing countries. A stylized model is developed to achieve three objectives: (1) to serve as a tool for determining optimal mix, size and timing of power generation types in the face of budget constraint, (2) to help decision makers appreciate the consequences of capacity expansion decisions on level of unserved electricity demand and its attendant impact on the national economy, and (3) to encourage the habit of periodic savings towards new generation capacity financing. The problem is modeled using a stochastic mixed-integer linear programming (MILP) technique under demand uncertainty. The effectiveness of the model, together with valuable insights derived from considering different levels of budget constraints are demonstrated using Ghana as a case study. The results indicate that at an annual savings equivalent to 0.75% of GDP, Ghana could finance the needed generation capacity to meet approximately 95% of its annual electricity demand between 2016 and 2035. Additionally, it is observed that as financial constraint becomes tighter, decisions on the mix of new generation capacities tend to be more costly compared to when sufficient funds are available.

  5. 24 CFR 1003.205 - Eligible planning, urban environmental design and policy-planning-management-capacity building...

    2010-04-01

    ... environmental design and policy-planning-management-capacity building activities. 1003.205 Section 1003.205... planning, urban environmental design and policy-planning-management-capacity building activities. (a... plans, general environmental studies, and strategies and action programs to implement plans, including...

  6. 24 CFR 570.205 - Eligible planning, urban environmental design and policy-planning-management-capacity building...

    2010-04-01

    ... environmental design and policy-planning-management-capacity building activities. 570.205 Section 570.205..., urban environmental design and policy-planning-management-capacity building activities. (a) Planning... known or suspected environmental contamination. (5) [Reserved] (6) Policy—planning—management—capacity...

  7. Aggregate Production Planning, Casestudy in a Medium-sized Industry of the Rubber Production Line in Ecuador.

    Rosero-Mantilla, César; Sánchez-Sailema, Mayra; Sánchez-Rosero, Carlos; Galleguillos-Pozo, Rosa

    2017-06-01

    This research aims to improve the productivity in the rubber line of a medium-sized industry by increasing the production capacities through the use of the Aggregate Production Planning model. For this purpose an analysis of the production processes of the line was made and the aggregate plan was defined evaluating two strategies: Exact Production Plan (Zero Inventory) and Constant Workforce Plan (Vary Inventory) by studying the costs of both inventory maintenance and workforce. It was also determined how the installed capacity was used with the standards of the rubber line and measures for decreasing production costs were proposed. It was proven that only 70% of the plant capacity was being used so it could be possible to produce more units and to obtain a bigger market for the products of this line.+

  8. Difference in membrane repair capacity between cancer cell lines and a normal cell line

    Frandsen, Stine Krog; McNeil, Anna K.; Novak, Ivana

    2016-01-01

    repair was investigated by disrupting the plasma membrane using laser followed by monitoring fluorescent dye entry over time in seven cancer cell lines, an immortalized cell line, and a normal primary cell line. The kinetics of repair in living cells can be directly recorded using this technique...... cancer cell lines (p immortalized cell line (p

  9. Integrating Robot Task Planning into Off-Line Programming Systems

    Sun, Hongyan; Kroszynski, Uri

    1988-01-01

    a system architecture for integrated robot task planning. It identifies and describes the components considered necessary for implementation. The focus is on functionality of these elements as well as on the information flow. A pilot implementation of such an integrated system architecture for a robot......The addition of robot task planning in off-line programming systems aims at improving the capability of current state-of-the-art commercially available off-line programming systems, by integrating modeling, task planning, programming and simulation together under one platform. This article proposes...... assembly task is discussed....

  10. The EPA-Wide Plan to Provide Solid Waste Management Capacity Assistance to Tribes

    This Plan is a strategy for building tribal capacity to manage solid waste. The Plan promotes the development and implementation of integrated waste management plans and describes how EPA will prioritize its resources to maximize environmental benefits.

  11. Timetable Design for Urban Rail Line with Capacity Constraints

    Yu-Ting Zhu

    2015-01-01

    Full Text Available To design an efficient and economical timetable for a heavily congested urban rail corridor, a scheduling model is proposed in this paper. The objective of the proposed model is to find the departure time of trains at the start terminal to minimize the system cost, which includes passenger waiting cost and operating cost. To evaluate the performance of the timetable, a simulation model is developed to simulate the detailed movements of passengers and trains with strict constraints of station and train capacities. It assumes that passengers who arrive early will have more chances to access a station and board a train. The accessing and boarding processes of passengers are all based on a first-come-first-serve basis. When a station is full, passengers unable to access must wait outside until the number of waiting passengers at platform falls below a given value. When a train is full, passengers unable to board must wait at the platform for the next train to arrive. Then, based on the simulation results, a two-stage genetic algorithm is introduced to find the best timetable. Finally, a numerical example is given to demonstrate the effectiveness of the proposed model and solution method.

  12. Developing a Framework for Effective Network Capacity Planning

    Yaprak, Ece

    2005-01-01

    As Internet traffic continues to grow exponentially, developing a clearer understanding of, and appropriately measuring, network's performance is becoming ever more critical. An important challenge faced by the Information Resources Directorate (IRD) at the Johnson Space Center in this context remains not only monitoring and maintaining a secure network, but also better understanding the capacity and future growth potential boundaries of its network. This requires capacity planning which involves modeling and simulating different network alternatives, and incorporating changes in design as technologies, components, configurations, and applications change, to determine optimal solutions in light of IRD's goals, objectives and strategies. My primary task this summer was to address this need. I evaluated network-modeling tools from OPNET Technologies Inc. and Compuware Corporation. I generated a baseline model for Building 45 using both tools by importing "real" topology/traffic information using IRD's various network management tools. I compared each tool against the other in terms of the advantages and disadvantages of both tools to accomplish IRD's goals. I also prepared step-by-step "how to design a baseline model" tutorial for both OPNET and Compuware products.

  13. Model for Assembly Line Re-Balancing Considering Additional Capacity and Outsourcing to Face Demand Fluctuations

    Samadhi, TMAA; Sumihartati, Atin

    2016-02-01

    The most critical stage in a garment industry is sewing process, because generally, it consists of a number of operations and a large number of sewing machines for each operation. Therefore, it requires a balancing method that can assign task to work station with balance workloads. Many studies on assembly line balancing assume a new assembly line, but in reality, due to demand fluctuation and demand increased a re-balancing is needed. To cope with those fluctuating demand changes, additional capacity can be carried out by investing in spare sewing machine and paying for sewing service through outsourcing. This study develops an assembly line balancing (ALB) model on existing line to cope with fluctuating demand change. Capacity redesign is decided if the fluctuation demand exceeds the available capacity through a combination of making investment on new machines and outsourcing while considering for minimizing the cost of idle capacity in the future. The objective of the model is to minimize the total cost of the line assembly that consists of operating costs, machine cost, adding capacity cost, losses cost due to idle capacity and outsourcing costs. The model develop is based on an integer programming model. The model is tested for a set of data of one year demand with the existing number of sewing machines of 41 units. The result shows that additional maximum capacity up to 76 units of machine required when there is an increase of 60% of the average demand, at the equal cost parameters..

  14. Railway line capacity consumption of different railway signalling systems under scheduled and disturbed conditions

    Goverde, R.M.P.; Corman, F.; D'Ariano, A.

    2013-01-01

    This paper evaluates the capacity consumption on a Dutch railway line both under scheduled and disturbed traffic conditions. For the scheduled condition the standard UIC compression method is used, while the computation of capacity consumption under disturbed conditions requires multiple simulation

  15. Capacity Constrained Routing Algorithms for Evacuation Route Planning

    Lu, Qingsong; George, Betsy; Shekhar, Shashi

    2006-01-01

    .... In this paper, we propose a new approach, namely a capacity constrained routing planner which models capacity as a time series and generalizes shortest path algorithms to incorporate capacity constraints...

  16. Organizational factors, planning capacity, and integration challenges constrain provincial planning processes for nutrition in decentralizing Vietnam.

    Lapping, Karin; Frongillo, Edward A; Nguyen, Phuong H; Coates, Jennifer; Webb, Patrick; Menon, Purnima

    2014-09-01

    Translating national policies and guidelines into effective action at the subnational level (e.g., province or region) is a prerequisite for ensuring an impact on nutrition. In several countries, including Vietnam, the focus of this paper, this process is affected by the quality of the decentralized process of planning and action. This study examined how provincial planning processes for nutrition occurred in Vietnam during 2009 and 2010. Key goals were to understand variability in processes across provinces, identify factors that influenced the process, and assess the usefulness of the process for individuals involved in planning and action. A qualitative case-study methodology was used. Data were drawn from interviews with 51 government officials in eight provinces. The study found little variability in the planning process among these eight provinces, probably due to a planning process that was predominantly a fiscal exercise within the confines of a largely centralized structure. Respondents were almost unanimous about the main barriers: a top-down approach to planning, limited human capacity for effective planning at subnational levels, and difficulty in integrating actions from multiple sectors. Provincial-level actors were deeply dissatisfied with the nature of their role in the process. Despite the rhetoric to the contrary, too much power is probably still retained at the central level. A strategic multiyear approach is needed to strengthen the provincial planning process and address many of the key barriers identified in this study.

  17. Rubber lining design for grinding mills: influence on economy and capacity

    Nillson, G

    1979-11-01

    There is a difference in design parameters between steel linings and rubber linings for grinding mills. The basic design parameters for rubber are described and a comparison is made between steel and rubber in different applications. If a rubber lining is correctly designed, it will give at least the same capacity as any other type of lining. A rubber lining can often be made thinner than other types of lining and, in such cases, the increased mill diameter will increase the capacity. What has been said above regarding capacity applies equally to grinding efficiency. The grind can sometimes be changed by altering the lifter height and lifter profile. Rubber linings of the correct quality and design will always give improved lining economy, except for large primary ball mills. We trust that new designs and rubber qualities will change the picture in the future. What is said about lining economy is especially true when taking reduced downtime and maintenance into consideration. The lining must be designed to reduce sliding over the shell, which leads to heavy wear. When used for dry grinding, the adverse effects of temperature must be observed.

  18. Characterization Plan for Soils Around Drain Line PLA-100115

    D. Shanklin

    2006-05-24

    This Characterization Plan supports the Hazardous Waste Management Act/Resource Conservation and Recovery Act (HWMA/RCRA) closure of soils that may have been contaminated by releases from drain line PLA-100115, located within the Idaho Nuclear Technology and Engineering Center at the Idaho National Laboratory Site. The requirements to address the closure of soils contaminated by a potential release from this line in a characterization plan was identified in the "HWMA/RCRA Less Than 90-day Generator Closure Report for the VES-SFE-126."

  19. Capacity and production planning with carbon emission constraints

    Govindan, Kannan; Song, Shuang; Xu, Lei

    2017-01-01

    This paper builds a two-stage, stochastic model to study capacity expansion problem in logistics under cap-and-trade and carbon tax regulations. The optimal capacity expansion and production decisions are obtained, and the effects of carbon emission regulations on capacity expansion are studied....... Through analytical study and a real case numerical analysis, we find that the carbon tax exhibits different impacts on optimal capacity expansion decisions in low tax rate and high tax rate, and the volatility of capacity investment cost has a larger impact on optimal capacity expansion than...... that of production cost....

  20. Modeling and forecasting of electrical power demands for capacity planning

    Al-Shobaki, Salman; Mohsen, Mousa

    2008-01-01

    This paper describes the development of forecasting models to predict future generation and electrical power consumption in Jordan. This is critical to production cost since power is generated by burning expensive imported oil. Currently, the National Electric Power Company (NEPCO) is using regression models that only accounts for trend dynamics in their planning of loads and demand levels. The models are simplistic and are based on generated energy historical levels. They produce results on yearly bases and do not account for monthly variability in demand levels. The paper presents two models, one based on the generated energy data and the other is based on the consumed energy data. The models account for trend, monthly seasonality, and cycle dynamics. Both models are compared to NEPCO's model and indicate that NEPCO is producing energy at levels higher than needed (5.25%) thus increasing the loss in generated energy. The developed models also show a 13% difference between the generated energy and the consumed energy that is lost due to transmission line and in-house consumption

  1. Modeling and forecasting of electrical power demands for capacity planning

    Al-Shobaki, Salman [Department of Industrial Engineering, Hashemite University, Zarka 13115 (Jordan); Mohsen, Mousa [Department of Mechanical Engineering, Hashemite University, Zarka 13115 (Jordan)

    2008-11-15

    This paper describes the development of forecasting models to predict future generation and electrical power consumption in Jordan. This is critical to production cost since power is generated by burning expensive imported oil. Currently, the National Electric Power Company (NEPCO) is using regression models that only accounts for trend dynamics in their planning of loads and demand levels. The models are simplistic and are based on generated energy historical levels. They produce results on yearly bases and do not account for monthly variability in demand levels. The paper presents two models, one based on the generated energy data and the other is based on the consumed energy data. The models account for trend, monthly seasonality, and cycle dynamics. Both models are compared to NEPCO's model and indicate that NEPCO is producing energy at levels higher than needed (5.25%) thus increasing the loss in generated energy. The developed models also show a 13% difference between the generated energy and the consumed energy that is lost due to transmission line and in-house consumption. (author)

  2. Transmission capacity assessment by probabilistic planning. An approach

    Lammintausta, M.

    2002-01-01

    The Finnish electricity markets participate in the Scandinavian markets, Nord-Pool. The Finnish market is free for marketers, producers and consumers. All these participants can be seen as customers of the transmission network, which in turn can be considered to be a market place in which electricity can be sold and bought. The Finnish transmission network is owned and operated by an independent company, Fingrid that has the full responsibility of the Finnish transmission system. The available transfer capacity of a transmission route is traditionally limited by deterministic security constraints. More efficient and flexible network utilisation could be achieved with probabilistic planning methods. This report introduces a simple and practical probabilistic approach for transfer limit and risk assessment. The method is based on the economical benefit and risk predictions. It uses also the existing results of deterministic data and it could be used side by side with the deterministic method. The basic concept and necessary equations for expected risks of various market players have been derived for further developments. The outage costs and thereby the risks of the market participants depend on how the system operator reacts to the faults. In the Finnish power system consumers will usually experience no costs due to the faults because of meshed network and counter trade method preferred by the system operator. The costs to the producers and dealers are also low because of the counter trade method. The network company will lose the cost of reparation, additional losses and cost of regulation power because of counter trades. In case power flows will be rearranged drastically because of aggressive strategies used in the electricity markets, the only way to fulfil the needs of free markets is that the network operator buys regulation power for short-term problems and reinforces the network in the long-term situations. The reinforcement is done if the network can not be

  3. Engineering task plan for steam line ramp calculations

    DeSantis, G.N.; Freeman, R.D.

    1994-01-01

    The purpose of this document is to provide an approved work plan to perform calculations that verify the load limits of a proposed ramp over a steam line at the back side (East side) of SY Farm in support of work package 2W-94-00812/K. The objective of this supporting document is to provide Operations with a set of checked calculations that verify the ramp over the steam line at SY Farm will support a fully loaded concrete mixer truck without affecting the steam line. The calculations will be performed by an engineers from Facility Systems and independently checked and reviewed by another engineer. The calculations may then be added to the work package. If Operations decides to make any configuration changes to the steam line or surrounding area, Operations shall have these changes documented by an Engineering Change Notice (ECN). This ECN can be done by Facility Systems or any other engineering organization at the direction of Operations

  4. Inspection logistics planning for multi-stage production systems with applications to semiconductor fabrication lines

    Chen, Kyle Dakai

    Since the market for semiconductor products has become more lucrative and competitive, research into improving yields for semiconductor fabrication lines has lately received a tremendous amount of attention. One of the most critical tasks in achieving such yield improvements is to plan the in-line inspection sampling efficiently so that any potential yield problems can be detected early and eliminated quickly. We formulate a multi-stage inspection planning model based on configurations in actual semiconductor fabrication lines, specifically taking into account both the capacity constraint and the congestion effects at the inspection station. We propose a new mixed First-Come-First-Serve (FCFS) and Last-Come-First-Serve (LCFS) discipline for serving the inspection samples to expedite the detection of potential yield problems. Employing this mixed FCFS and LCFS discipline, we derive approximate expressions for the queueing delays in yield problem detection time and develop near-optimal algorithms to obtain the inspection logistics planning policies. We also investigate the queueing performance with this mixed type of service discipline under different assumptions and configurations. In addition, we conduct numerical tests and generate managerial insights based on input data from actual semiconductor fabrication lines. To the best of our knowledge, this research is novel in developing, for the first time in the literature, near-optimal results for inspection logistics planning in multi-stage production systems with congestion effects explicitly considered.

  5. A Modelling Approach for Integrated Planning of Port Capacity- Trade-Offs in Rotterdam Investment Planning

    Sander Dekker

    2006-03-01

    Full Text Available This paper presents a modelling approach for planning ofport capacity. The approach integrates port commercial andpublic interests. It further incorporates route competition andautonomous demand growth. It is applied to port expansion,which can be considered as a strategy for an individual port todeal with route competition. The basis for solving this planningproblem comprises an analysis of port demand and supply in apartial equilibrium model. With such an approach, the reactionof a single port on the change in a transport network comprisingalternative routes to a hinterland destination can be simulated.To establish the optimal expansion strategy, port expansion iscombined with congestion pricing. This is used for the simultaneousdetermination of 1 optimal expansion size, and 2 investmentrecovery period. The modelling approach will be appliedto Rotterdam port focusing on port expansion by means ofland reclamation. The scenmio of the entry of a new competingroute via the Italian port Gioia Tauro is used to address sometrade-offs in Rotterdam investment planning.

  6. Analysis of Power Network for Line Reactance Variation to Improve Total Transmission Capacity

    Ikram Ullah

    2016-11-01

    Full Text Available The increasing growth in power demand and the penetration of renewable distributed generations in competitive electricity market demands large and flexible capacity from the transmission grid to reduce transmission bottlenecks. The bottlenecks cause transmission congestion, reliability problems, restrict competition, and limit the maximum dispatch of low cost generations in the network. The electricity system requires efficient utilization of the current transmission capability to improve the Available Transfer Capability (ATC. To improve the ATC, power flow among the lines can be managed by using Flexible AC Transmission System (FACTS devices as power flow controllers, which alter the parameters of power lines. It is important to place FACTS devices on suitable lines to vary the reactance for improving Total Transmission Capacity (TTC of the network and provide flexibility in the power flow. In this paper a transmission network is analyzed based on line parameters variation to improve TTC of the interconnected system. Lines are selected for placing FACTS devices based on real power flow Performance Index (PI sensitivity factors. TTC is computed using the Repeated Power Flow (RPF method using the constraints of lines thermal limits, bus voltage limits and generator limits. The reactance of suitable lines, selected on the basis of PI sensitivity factors are changed to divert the power flow to other lines with enough transfer capacity available. The improvement of TTC using line reactance variation is demonstrated with three IEEE test systems with multi-area networks. The results show the variation of the selected lines’ reactance in improving TTC for all the test networks with defined contingency cases.

  7. The Capacity to Integrate and Deal with Environmental Issues in Local Transport Policy and Planning

    Hansen, Carsten Jahn

    2002-01-01

    The article identifies and discuss the capacity to integrate and deal with environmental issues in local transport policy-making and planning processes.......The article identifies and discuss the capacity to integrate and deal with environmental issues in local transport policy-making and planning processes....

  8. Demand and capacity planning in the emergency department: how to do it.

    Higginson, I; Whyatt, J; Silvester, K

    2011-02-01

    Unless emergency departments have adequate capacity to meet demand, they will fail to meet clinical and performance standards and will be operating in the 'coping zone'. This carries risks both for staff and patients. As part of a quality improvement programme, the authors undertook an in-depth analysis of demand and capacity for an emergency department in the UK. The paper describes this rigorous approach to capacity planning, which draws on techniques from other industries. Proper capacity planning is vital, but is often poorly done. Planning using aggregated data will lead to inadequate capacity. Understanding demand, and particularly the variation in that demand, is critical to success. Analysis of emergency department demand and capacity is the first step towards effective workforce planning and process redesign.

  9. Effects of Manufacturing Firm’s Capacity Planning on Performance of the Firm

    Kifordu Anthony

    2017-12-01

    Full Text Available This study investigated capacity planning and performance in the manufacturing sector in the Southeastern States of Nigeria based on selected Brewing industries. The population of the study was 740 staff of the brewing industry in South-Eastearn Nigeria. The sample size of 509 was obtained using a Taro Yamani’s statistical formula. The study used questionnaire and oral interview guide for data gathering. A test- retest stood completed using Spearman’s rank correlation, giving a coefficient of 0.9. Findings revealed that capacity planning significantly enriched economic performance of the industry studied. There existed a strong affirmative relationship among capacity necessities planning and resources requirements planning. The paper suggested use of capacity planning as a technique to improve all performance factors. Similarly, performance advantage subsist from the correlation of volume requirements plans and resources requirements planning. The paper summarily held the position that volume preparation improved the economic performance in the industry under review. This inferred that goals achievement is possible. Likewise, the finding of substantial constructive association between volume supplies planning and resources supplies planning inferred an affirmative communication between the variables. This meant that resources supplies planning which was a method of organizing the detailed production plans could lead to an improvement of capacity supplies planning. That is to say, they are taking future decisions on the substances required for production capability of the brewing facility.

  10. Early environmental planning: A process for power line corridor selection

    Haagenstad, T.; Bare, C.M.

    1998-01-01

    Los Alamos National Laboratory (LANL) conducted an environmental planning study in the fall of 1997 to help determine the best alternative for upgrading the Laboratory's electrical power system. Alternatives considered included an on-site power generation facility and two corridors for a 10-mile-long 115-kV power line. This planning process was conducted prior to the formal National Environmental Policy Act (NEPA) review. The goals were to help select the best proposed action, to recommend modifications and mitigation measures for each alternative for a more environmentally sound project, and to avoid potential delays once the formal Department of Energy review process began. Significant constraints existed from a planning perspective, including operational issues such as existing outdoor high explosives testing areas, as well as environmental issues including threatened and endangered species habitats, multiple archeological sites, contaminated areas, and aesthetics. The study had to be completed within 45 days to meet project schedule needs. The process resulted in a number of important recommendations. While the construction and operation of the on-site power generation facility could have minimal environmental impacts, the need for a new air quality permit would create severe cost and schedule constraints for the project. From an environmental perspective, construction and operation of a power line within either corridor was concluded to be a viable alternative. However, impacts with either corridor would have to be reduced through specific recommended alignment modifications and mitigation measures

  11. Planning Decrements in Healthy Aging: Mediation Effects of Fluid Reasoning and Working Memory Capacity.

    Köstering, Lena; Leonhart, Rainer; Stahl, Christoph; Weiller, Cornelius; Kaller, Christoph P

    2016-03-01

    Although age-related differences in planning ability are well known, their cognitive foundations remain a matter of contention. To elucidate the specific processes underlying planning decrements in older age, the relative contributions of fluid reasoning, working memory (WM) capacity, and processing speed to accuracy on the Tower of London (TOL) planning task were investigated. Mediation analyses were used to relate overall and search depth-related TOL accuracy from older (N = 106; 60-89 years) and younger adults (N = 69; 18-54 years) to age and measures of fluid reasoning, WM capacity, and speed. For overall planning, fluid abilities mediated the effects of age, WM capacity, and speed in older adults. By contrast, fluid abilities and WM capacity mediated each other in younger adults. For planning accuracy under low demands on the depth of search, WM capacity was specifically important in older age, whereas younger adults recruited both WM capacity and fluid reasoning. Under high search-depth-demands, fluid abilities underlay the cognitive operations critical for resolving move interdependencies in both age groups. Fluid abilities and WM capacity undergo significant changes from younger to older age in their unique contribution to planning, which might represent a mechanism whereby planning decrements in older age are brought about. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Capacity building in the IAEA Action Plan on Nuclear Safety

    Caruso, Gustavo

    2014-01-01

    Conclusion and Future Challenges: • Momentum on Nuclear Safety; • To continue strengthening, developing, maintaining and implementing capacity building programmes, including education, training and exercises at the national, regional and international levels; • To ensure sufficient and competent human resources necessary to assume responsibility for safety; • To incorporate lessons learned from the accident based on the IEMs and IAEA Fukushima Report

  13. Capacity Building through Geospatial Education in Planning and School Curricula

    Kumar, P.; Siddiqui, A.; Gupta, K.; Jain, S.; Krishna Murthy, Y. V. N.

    2014-11-01

    Geospatial technology has widespread usage in development planning and resource management. It offers pragmatic tools to help urban and regional planners to realize their goals. On the request of Ministry of Urban Development, Govt. of India, the Indian Institute of Remote Sensing (IIRS), Dehradun has taken an initiative to study the model syllabi of All India Council for Technical Education for planning curricula of Bachelor and Master (five disciplines) programmes. It is inferred that geospatial content across the semesters in various planning fields needs revision. It is also realized that students pursuing planning curricula are invariably exposed to spatial mapping tools but the popular digital drafting software have limitations on geospatial analysis of planning phenomena. Therefore, students need exposure on geospatial technologies to understand various real world phenomena. Inputs were given to seamlessly merge and incorporate geospatial components throughout the semesters wherever seems relevant. Another initiative by IIRS was taken to enhance the understanding and essence of space and geospatial technologies amongst the young minds at 10+2 level. The content was proposed in a manner such that youngsters start realizing the innumerable contributions made by space and geospatial technologies in their day-to-day life. This effort both at school and college level would help in not only enhancing job opportunities for young generation but also utilizing the untapped human resource potential. In the era of smart cities, higher economic growth and aspirations for a better tomorrow, integration of Geospatial technologies with conventional wisdom can no longer be ignored.

  14. A Departure Time Choice for Morning Commute Considering Train Capacity of a Rail Transit Line

    Jia Feng; Baohua Mao; Zhijie Chen; Yun Bai; Minggao Li

    2013-01-01

    Every commuter utilizing urban rail transit decides the departure time from home to a station according to individual judgment for the biggest possibility to board a train as soon as possible after the arrival. Therefore, the departure time choice behavior of the commuters is complicated especially when the transport capacity of this transit line cannot meet the travel demands of its users in rush hour. This research first develops a travel cost function mainly considering the travel time to ...

  15. Essays on investment planning in electricity generating capacity

    Gonzalez-Gomez, Jorge

    In the first part of this study we develop and analyze two mathematical models that incorporate a time changing demand for electricity and uncertainty of input prices. The first model highlights the shortcomings in assuming a constant plant utilization under uncertainty of input prices and the effects of such assumption on the optimal investment in electricity generating capacity in a simple two period model. The second model presents sufficient restrictions to the optimal investment in electricity generating capacity problem to allow for a recursive solution. The necessary restrictions are extremely limiting to the extend that we found a solution for very simple scenarios. In our opinion, the problem is better handled in a case by case basis rather than under a general dynamic framework. Following the spirit of our conclusions of the first part of our study, in the second part we provide a methodology to simulate long-term natural gas prices, we analyze the investment prospects of nuclear and natural gas generating capacity in Mexico and provide a constraint approach for the optimal generation of hydroelectric plants in the Mexican hydroelectric system. These three problems belong to the solution of the optimal investment in electricity generating capacity in Mexico. To simulate the uncertainty of natural gas prices, we assume that natural gas prices are the sum of two stochastic processes: short-term and long-term variability. We characterize the short-term variability of natural gas prices using an Exponential General Autoregressive Conditional Heteroskedastic (EGARCH) model. The uncertainty of the long-term variability of natural gas prices is based on the long-term natural gas prices scenarios of the National Energy Modeling System of the Energy Information Administration. Equipped with a methodology to simulate long-term natural gas prices, we investigate the investment prospects of nuclear and natural gas generating capacity in Mexico using the levelized

  16. Powering the people: India's capacity expansion plans

    Patel, S.

    2009-05-15

    India has become a global business power even though hundreds of millions of its citizens still live in poverty. To sustain economic growth and lift its people out of poverty, India needs more and more reliable power. Details of government plans for achieving those goals demonstrate that pragmatism may be in shorter supply than ambition and political will. 1 ref., 12 figs., 1 tab.

  17. The Impact of Noise Models on Capacity Performance of Distribution Broadband over Power Lines Networks

    Athanasios G. Lazaropoulos

    2016-01-01

    Full Text Available This paper considers broadband potential of distribution Broadband over Power Lines (BPL networks when different well-known noise models of the BPL literature are applied. The contribution of this paper is twofold. First, the seven most representative and used noise models of the BPL literature are synopsized in this paper. With reference to this set, the broadband performance of a great number of distribution BPL topologies either Overhead (OV or Underground (UN, either Medium-Voltage (MV or Low-Voltage (LV, is investigated in terms of suitable capacity metrics. Second, based on the proposed capacity metrics, a comparative capacity analysis is performed among various well-validated noise models. Through the careful study of its results, it is demonstrated that during capacity computations of distribution BPL networks, the flat Additive White Gaussian Noise (FL noise model can be comfortably assumed as an efficient noise model either in 3–30 MHz or in 3–88 MHz frequency range since its capacity differences with the other well-proven noise models are negligible.

  18. BALANCE CAPACITY WITH VARIABILITY CAUSED BY HUMAN FACTOR: AN APPLICATION IN A LINE WITH MONTE CARLO SIMULATION

    Augusto Sandes Mendes

    2016-07-01

    Full Text Available The variation in processing times due to the human factor between the working stations of a production line can generate queues resulting in a higher cost to the productive process. The objective of this study was to apply Monte Carlo simulation to balance the capacity of a production line with stations suffering variability in processing time due to the human factor. Simulations of the current situation of the production line were performed by comparing it with a proposal to align capacity with the production restriction in order to reduce inventories process while maintaining full capacity of the line. To develop the study, the selection involves the case of a company’s production line in the metal industry that produces machinery and products for metalworking area. The results allowed pointing suggestions for the company to reduce in-process inventory, keeping then total capacity of the line.

  19. Building hospital capacity planning mechanisms in Poland: The impact of 2016/2017 regulatory changes.

    Dubas-Jakóbczyk, Katarzyna; Sowada, Christoph; Domagała, Alicja; Więckowska, Barbara

    2018-02-07

    Capacity planning is a crucial component of modern health care governance. The aim of this paper is to analyze the requirements that need to be met to build effective hospital capacity planning mechanisms in Poland. In this context, the recent regulatory changes strongly influencing hospital sector functioning, including introduction of health care needs maps, capital investment assessment, and hospital network regulations, are analyzed. Some possible ways forward, based on review of international experiences in hospital capacity planning, are discussed. Applied methods include literature review and analysis of statistical data as well as desk analysis of key national regulations related to hospital sector. Results indicate that at the system level, the process of capacity planning involves 4 elements: capital investment in facilities, equipment, and technology; service delivery; allocation of staff; and financial resources. For hospital capacity planning to be effective, the strategic decision at the macrolevel must be complemented by appropriate management of individual hospitals. The major challenge of building hospital capacity planning mechanism in Poland is imbedding it into the overall health system strategy. Because of the lack of such a strategy, the practical implementation of the ad hoc changes, which have been introduced, shows some inconsistencies. The regulations implemented between 2016 and 2017 provided a basis for hospital capacity planning, yet still need evaluation and adjustments. Also, including a mechanism for human resources planning is of crucial importance. The regulations should provide incentives for reducing oversized hospital infrastructure with simultaneous development of the long-term and coordinated care models. Copyright © 2018 John Wiley & Sons, Ltd.

  20. Capacity planning for Carrier Ethernet LTE backhaul networks

    Checko, Aleksandra; Ellegaard, Lars; Berger, Michael Stübert

    2012-01-01

    With the introduction of LTE networks operators need to plan a new, IP-based mobile backhaul. In this paper, we provide recommendation on dimensioning LTE backhaul networks links using three methods: delay-, dimensioning formula- and overbooking factor-based. Results are obtained from OPNET simul...... and verified. Simulation in this work proves that Carrier Ethernet, one of the candidate technologies for mobile backhaul, protects the network from users that want to flood the network with their data and manages to keep the delay experienced by other users low....... simulations with traffic model based on traffic forecast for 2015. A delay-based approach gives recommended bandwidth for expected number of users. A dimensioning formula is proposed to calculate link bandwidth when mean value of aggregated traffic in the network is known. An overbooking factor is calculated...

  1. A financial planning model for estimating hospital debt capacity.

    Hopkins, D S; Heath, D; Levin, P J

    1982-01-01

    A computer-based financial planning model was formulated to measure the impact of a major capital improvement project on the fiscal health of Stanford University Hospital. The model had to be responsive to many variables and easy to use, so as to allow for the testing of numerous alternatives. Special efforts were made to identify the key variables that needed to be presented in the model and to include all known links between capital investment, debt, and hospital operating expenses. Growth in the number of patient days of care was singled out as a major source of uncertainty that would have profound effects on the hospital's finances. Therefore this variable was subjected to special scrutiny in terms of efforts to gauge expected demographic trends and market forces. In addition, alternative base runs of the model were made under three distinct patient-demand assumptions. Use of the model enabled planners at the Stanford University Hospital (a) to determine that a proposed modernization plan was financially feasible under a reasonable (that is, not unduly optimistic) set of assumptions and (b) to examine the major sources of risk. Other than patient demand, these sources were found to be gross revenues per patient, operating costs, and future limitations on government reimbursement programs. When the likely financial consequences of these risks were estimated, both separately and in combination, it was determined that even if two or more assumptions took a somewhat more negative turn than was expected, the hospital would be able to offset adverse consequences by a relatively minor reduction in operating costs. PMID:7111658

  2. Optimal Capacity Proportion and Distribution Planning of Wind, Photovoltaic and Hydro Power in Bundled Transmission System

    Ye, X.; Tang, Q.; Li, T.; Wang, Y. L.; Zhang, X.; Ye, S. Y.

    2017-05-01

    The wind, photovoltaic and hydro power bundled transmission system attends to become common in Northwest and Southwest of China. To make better use of the power complementary characteristic of different power sources, the installed capacity proportion of wind, photovoltaic and hydro power, and their capacity distribution for each integration node is a significant issue to be solved in power system planning stage. An optimal capacity proportion and capacity distribution model for wind, photovoltaic and hydro power bundled transmission system is proposed here, which considers the power out characteristic of power resources with different type and in different area based on real operation data. The transmission capacity limit of power grid is also considered in this paper. Simulation cases are tested referring to one real regional system in Southwest China for planning level year 2020. The results verify the effectiveness of the model in this paper.

  3. Communicative Planning As Institutional Capacity Building: From Discourse/Network To Opportunity

    Delik Hudalah

    2013-05-01

    Full Text Available The paper redefines the ideas about communicative planning as not only participatory and democratic practice but also capacity building oriented toward the improvement of governance styles and consciousness. So far capacity building has focused on the exploitation of social resources internal to actors. These internal resources include knowledge (argumentation, debate, discourse formation etc and relational (network, coalition, alliance etc building. The paper argues that in dealing with very complex planning problems characterized by fragmented and uncertain institutional systems, the internal resources need to be coupled with the exploration of resources external to actors, namely the political opportunity structure and moment of opportunity. The analysis implies that the performance of communicative decision-making process as capacity building can be assessed in three aspects: strategic and inclusive actors’ involvement, the building of actors’ awareness on neglected but important planning issues and agendas, and consistency and deliberation in realizing and delivering agreed planning ideas, frameworks and decisions.

  4. Cryptotanshinone has diverse effects on cell cycle events in melanoma cell lines with different metastatic capacity

    Punchard, Neville

    2011-01-01

    Background and Purpose: Cryptotanshinone (CTs) is a major active component of Salvia miltiorrhiza, which is often used as Chinese herbal medicine in cancer therapy. Here, we systematically assessed the anti-tumor effect of CTs on two melanoma cell lines with low/high metastatic capacity (B16/B16BL6). Experimental Approach: MTT and LDH assays were used to evaluate cell growth and cytotoxicity. We assessed the effect of CTs on cell apoptosis or proliferation by Annexin V, TUNEL or BrdU assay. C...

  5. Adaptive Planning: Understanding Organizational Workload to Capability/ Capacity through Modeling and Simulation

    Hase, Chris

    2010-01-01

    In August 2003, the Secretary of Defense (SECDEF) established the Adaptive Planning (AP) initiative [1] with an objective of reducing the time necessary to develop and revise Combatant Commander (COCOM) contingency plans and increase SECDEF plan visibility. In addition to reducing the traditional plan development timeline from twenty-four months to less than twelve months (with a goal of six months)[2], AP increased plan visibility to Department of Defense (DoD) leadership through In-Progress Reviews (IPRs). The IPR process, as well as the increased number of campaign and contingency plans COCOMs had to develop, increased the workload while the number of planners remained fixed. Several efforts from collaborative planning tools to streamlined processes were initiated to compensate for the increased workload enabling COCOMS to better meet shorter planning timelines. This paper examines the Joint Strategic Capabilities Plan (JSCP) directed contingency planning and staffing requirements assigned to a combatant commander staff through the lens of modeling and simulation. The dynamics of developing a COCOM plan are captured with an ExtendSim [3] simulation. The resulting analysis provides a quantifiable means by which to measure a combatant commander staffs workload associated with development and staffing JSCP [4] directed contingency plans with COCOM capability/capacity. Modeling and simulation bring significant opportunities in measuring the sensitivity of key variables in the assessment of workload to capability/capacity analysis. Gaining an understanding of the relationship between plan complexity, number of plans, planning processes, and number of planners with time required for plan development provides valuable information to DoD leadership. Through modeling and simulation AP leadership can gain greater insight in making key decisions on knowing where to best allocate scarce resources in an effort to meet DoD planning objectives.

  6. Actual practical considerations about overhead line engineering. Planning of overhead lines is booming; Aktuelle praktische Betrachtung der Freileitungstechnik. Freileitungsplanung boomt

    Bueckner, W.F.

    2007-04-30

    The power breakdowns we encountered in March 2006 due to extreme weather conditions and in November 2006 due to overload of overhead lines made overhead line techniques more interesting. After pausing for decades, technical development and investments for overhead lines in Germany become necessary again, meaning reconstructions and new constructions worth several millions of investment. An additional reason for this is given by the Federal Government's request for the construction of new power plants and overhead lines as well as by the energy plan of the EU-Commission. The power supplier have begun planning already. These plans require new and economical overhead lines. Proposals and practical examples are shown in the following article.

  7. Planning of overhead contact lines and simulation of the pantograph running; Oberleitungsplanung und Simulation des Stromabnehmerlaufes

    Hofbauer, Gerhard [ALPINE-ENERGIE Oesterreich GmbH, Linz (Austria); Hofbauer, Werner

    2009-07-01

    Using the software FLTG all planning steps for overhead contact lines can be carried out based on the parameters of the contact line type and the line data. Contact line supports and individual spans are presented graphically. The geometric interaction of pantograph and contact line can be simulated taking into account the pantograph type, its sway and the wind action. Thus, the suitability of a line for the interoperability of the transEuropean rail system can be demonstrated. (orig.)

  8. Learners’ processes during pre-task planning and Working Memory Capacity

    Maria da Gloria Tavares

    2016-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2016v69n1p79 The present study is part of a larger scale research (Guará-Tavares, 2011, 2013 that investigates the relationship among working memory capacity, pre-task planning, and L2 speech performance. The aim of the study was to analyze 1 what processes learners engage during pre-task planning, and 2 whether higher and lower working memory spans engage in different processes during pre-task planning. Learners’ processes were accessed by means of think aloud protocols and a retrospective interview. Working memory capacity was measured by the Speaking Span Test. Results show that learners engage mainly in organization of ideas, rehearsal, lexical searches, and monitoring.. Moreover, higher spans employ significantly more metacognitive strategies during planning when compared to lower spans.

  9. Capacity Planning for Batch and Perfusion Bioprocesses Across Multiple Biopharmaceutical Facilities

    Siganporia, Cyrus C; Ghosh, Soumitra; Daszkowski, Thomas; Papageorgiou, Lazaros G; Farid, Suzanne S

    2014-01-01

    Production planning for biopharmaceutical portfolios becomes more complex when products switch between fed-batch and continuous perfusion culture processes. This article describes the development of a discrete-time mixed integer linear programming (MILP) model to optimize capacity plans for multiple biopharmaceutical products, with either batch or perfusion bioprocesses, across multiple facilities to meet quarterly demands. The model comprised specific features to account for products with fe...

  10. Impact of Operating Rules on Planning Capacity Expansion of Urban Water Supply Systems

    de Neufville, R.; Galelli, S.; Tian, X.

    2017-12-01

    This study addresses the impact of operating rules on capacity planning of urban water supply systems. The continuous growth of metropolitan areas represents a major challenge for water utilities, which often rely on industrial water supply (e.g., desalination, reclaimed water) to complement natural resources (e.g., reservoirs). These additional sources increase the reliability of supply, equipping operators with additional means to hedge against droughts. How do their rules for using industrial water supply impact the performance of water supply system? How might it affect long-term plans for capacity expansion? Possibly significantly, as demonstrated by the analysis of the operations and planning of a water supply system inspired by Singapore. Our analysis explores the system dynamics under multiple inflow and management scenarios to understand the extent to which alternative operating rules for the use of industrial water supply affect system performance. Results first show that these operating rules can have significant impact on the variability in system performance (e.g., reliability, energy use) comparable to that of hydro-climatological conditions. Further analyses of several capacity expansion exercises—based on our original hydrological and management scenarios—show that operating rules significantly affect the timing and magnitude of critical decisions, such as the construction of new desalination plants. These results have two implications: Capacity expansion analysis should consider the effect of a priori uncertainty about operating rules; and operators should consider how their flexibility in operating rules can affect their perceived need for capacity.

  11. Determination of planning capacity and layout criteria of outdoor recreation projects

    Lier, van H.N.

    1973-01-01


    When meeting the increasing demand for outdoor recreation projects, problems arise concerning location, planning capacity and layout. A system has been developed to solve the two last mentioned problems. Special attention is paid to inland beaches in the Netherlands. To apply the system two

  12. Building and measuring infrastructure and capacity for community health assessment and health improvement planning in Florida.

    Abarca, Christine; Grigg, C Meade; Steele, Jo Ann; Osgood, Laurie; Keating, Heidi

    2009-01-01

    COMPASS (Comprehensive Assessment, Strategic Success) is the Florida Department of Health's community health assessment and health improvement planning initiative. Since 2002, COMPASS built state and county health department infrastructure to support a comprehensive, systematic, and integrated approach to community health assessment and planning. To assess the capacity of Florida's 67 county health departments (CHDs) to conduct community health assessment and planning and to identify training and technical assistance needs, COMPASS surveyed the CHDs using a Web-based instrument annually from 2004 through 2008. Response rate to the survey was 100 percent annually. In 2007, 96 percent of CHDs reported conducting assessment and planning within the past 3 years; 74 percent used the MAPP (Mobilizing for Action through Planning and Partnerships) framework. Progress was greater for the organizational and assessment phases of the MAPP-based work; only 10 CHDs had identified strategic priorities in 2007, and even fewer had implemented strategies for improving health. In 2007, the most frequently requested types of training were measuring success, developing goals and action plans, and using qualitative data; technical assistance was most frequently requested for program evaluation and writing community health status reports. Florida's CHDs have increased their capacity to conduct community health assessment and planning. Questions remain about sustaining these gains with limited resources.

  13. Development of a regional capacity expansion plan in the Russian Federation. Application of the WASP Model

    Chernilin, Yu.; Kononov, S.; Zakharova, E.; Kagramanyan, V.; Malenkov, A.

    1997-01-01

    The Wien Automatic System Planning Package (WASP) is used for the development of optimal capacity expansion plans in Russia. The object of the WASP study is the Central power pool, which is the largest power pool in Russia and has an essential share of nuclear power in electricity generation. The objective of the study is to assess the long-term competitiveness of nuclear power in the region. The major features of the power system analyzed with WASP are the following: 1) four types of electricity generators are considered: condensity fossil fuel plants, cogeneration fossil fuel plants, nuclear power plants and hydraulic plants; 2) nine fuel categories are considered: gas/fuel oil fuel, several types of coal and several nuclear fuels; 3) escalation of capital, operation and maintenance, and fuel costs as a result of economic transition is explicitly modeled. Under these assumptions, a regional optimal capacity expansion plan is developed that showed the following: (a) Until 2004 there is no need for new electricity generation capacities due to the drop in demand in the 90s, certain lifetime margin of existing capacities, committed additions of co-generators and planned refurbishment/repowering measures; (b) The structure of the optimal capacity mix confirms that nuclear power can retain its role as one of the major electricity generation sources in the region. The most important factor with a positive of effect upon the competitiveness of nuclear power plants is the projected escalation of the prices of fossil fuels; (c) The application of WASP has proved that the model can serve as a valuable planning tool at the power pool level in Russia. (author). 14 refs, 8 figs, 10 tabs

  14. Development of a regional capacity expansion plan in the Russian Federation. Application of the WASP Model

    Chernilin, Yu; Kononov, S; Zakharova, E [Russian Research Inst. ` ` Kurchatov Inst.` ` , Moscow (Russian Federation); Kagramanyan, V; Malenkov, A [Institute of Physics and Power Engineering, Obninsk (Russian Federation)

    1997-09-01

    The Wien Automatic System Planning Package (WASP) is used for the development of optimal capacity expansion plans in Russia. The object of the WASP study is the Central power pool, which is the largest power pool in Russia and has an essential share of nuclear power in electricity generation. The objective of the study is to assess the long-term competitiveness of nuclear power in the region. The major features of the power system analyzed with WASP are the following: 1) four types of electricity generators are considered: condensity fossil fuel plants, cogeneration fossil fuel plants, nuclear power plants and hydraulic plants; 2) nine fuel categories are considered: gas/fuel oil fuel, several types of coal and several nuclear fuels; 3) escalation of capital, operation and maintenance, and fuel costs as a result of economic transition is explicitly modeled. Under these assumptions, a regional optimal capacity expansion plan is developed that showed the following: (a) Until 2004 there is no need for new electricity generation capacities due to the drop in demand in the 90s, certain lifetime margin of existing capacities, committed additions of co-generators and planned refurbishment/repowering measures; (b) The structure of the optimal capacity mix confirms that nuclear power can retain its role as one of the major electricity generation sources in the region. The most important factor with a positive of effect upon the competitiveness of nuclear power plants is the projected escalation of the prices of fossil fuels; (c) The application of WASP has proved that the model can serve as a valuable planning tool at the power pool level in Russia. (author). 14 refs, 8 figs, 10 tabs.

  15. An optimisation approach for capacity planning: modelling insights and empirical findings from a tactical perspective

    Andréa Nunes Carvalho

    2017-09-01

    Full Text Available Abstract The academic literature presents a research-practice gap on the application of decision support tools to address tactical planning problems in real-world organisations. This paper addresses this gap and extends a previous action research relative to an optimisation model applied for tactical capacity planning in an engineer-to-order industrial setting. The issues discussed herein raise new insights to better understand the practical results that can be achieved through the proposed model. The topics presented include the modelling of objectives, the representation of the production process and the costing approach, as well as findings regarding managerial decisions and the scope of action considered. These insights may inspire ideas to academics and practitioners when developing tools for capacity planning problems in similar contexts.

  16. Stability measures for rolling schedules with applications to capacity expansion planning, master production scheduling, and lot sizing

    Kimms, Alf

    1996-01-01

    This contribution discusses the measurement of (in-)stability of finite horizon production planning when done on a rolling horizon basis. As examples we review strategic capacity expansion planning, tactical master production schedulng, and operational capacitated lot sizing.

  17. Comparisons of recent growth in actual demand, planned demand, and planned generating capacity at U. S. electric utilities

    Bopp, A.E. (James Madison Univ., Harrisonburg, VA (United States))

    1994-12-01

    During the winter of 1993, a number of U.S. electric utilities and some regional power pools discovered that current load exceeded generating capacity. Load restrictions followed, as entire regions-not just isolated utilities or even states-cut back. Was 1993 a typical, or simply a preview of the future If a preview, how did this shortage occur For a number of years, utilities, regulatory agencies, and power pools have been planning to add capacity at a much lower rate than the rate at which load has been growing. The National Electricity Reliability Council (NERC) has projected that eight of it's nine regions will have demand growth exceed capacity growth. The only region where capacity is growing faster is in the Texas Region. There are four reasons behind this shortage: excess capacity in the 1980's, disbelief in current forecasts, passage of the Clean Air act bringing stricter regulation on power plants, and the herd mentality where utilities have all delayed new plant construction.

  18. Optimal Pricing and Production Master Planning in a Multiperiod Horizon Considering Capacity and Inventory Constraints

    Neale R. Smith

    2009-01-01

    Full Text Available We formulate and solve a single-item joint pricing and master planning optimization problem with capacity and inventory constrains. The objective is to maximize profits over a discrete-time multiperiod horizon. The solution process consists of two steps. First, we solve the single-period problem exactly. Second, using the exact solution of the single-period problem, we solve the multiperiod problem using a dynamic programming approach. The solution process and the importance of considering both capacity and inventory constraints are illustrated with numerical examples.

  19. Higher capacity, lower carbon dioxide emissions. Idle power compensation in HV lines; Mehr Kapazitaet, weniger Kohlendioxid. Blindleistungskompensation bei Hochspannungsleitungen

    Auer, Jan-Hendrik von [Alstom Grid GmbH, Berlin (Germany). Team Leistungselektronik und Kompensationsanlagen

    2012-07-01

    Even today, many HP lines have reached their limits. It is therefore highly urgent to find measures for optimum utilization of the available overhead transmssion capacities, e.g. by idle power compensation. Together with a filter for harmonics reduction, this will ensure higher grid stability and enhance transport capacities while reducing transport losses, thus saving money and reducing CO{sub 2} emissions. (orig./AKB)

  20. Analysis quality of content digital plan of cadastre lines (underground installation

    Marinković Goran

    2016-01-01

    Full Text Available This work presents the results of research quality digital geodetic plans lines and underground installations. The study included the creation of a digital geodetic plan sewerage network vectorization of analogue geodetic plans and creation of digital geodetic plan of the same details from the original data survey and maintenance survey. Based on research results the analysis of the accuracy and reliability digital geodetic plan created vectoring analogue plan or 'digitizing from the screen'. The results obtained in this work, the can be use not only in the Republic of Serbia, but also in other countries where digitalization of geodetic plans are increasingly gaining in importance.

  1. Dynamic supply chain network design with capacity planning and multi-period pricing

    Fattahi, Mohammad; Mahootchi, Masoud; Govindan, Kannan

    2015-01-01

    This paper addresses a new problem in designing and planning a multi-echelon and multi-product supply chain network over a multi-period horizon in which customer zones have price-sensitive demands. Based on price-demand relationships, a generic method is presented to obtain price levels...... for products and then, a mixed-integer linear programming model is developed. Due to the problem intractability, a simulated annealing algorithm that uses some developed linear relaxation-based heuristics for capacity planning and pricing is presented. Numerical results demonstrate the significance...

  2. Creation of inpatient capacity during a major hospital relocation: lessons for disaster planning.

    Jen, Howard C; Shew, Stephen B; Atkinson, James B; Rosenthal, J Thomas; Hiatt, Jonathan R

    2009-09-01

    To identify tools to aid the creation of disaster surge capacity using a model of planned inpatient census reduction prior to relocation of a university hospital. Prospective analysis of hospital operations for 1-week periods beginning 2 weeks (baseline) and 1 week (transition) prior to move day; analysis of regional hospital and emergency department capacity. Large metropolitan university teaching hospital. Hospital census figures and patient outcomes. Census was reduced by 36% from 537 at baseline to 345 on move day, a rate of 18 patients/d (P emergency operations was unchanged. Hospital admissions were decreased by 42%, and the adjusted discharges per occupied bed were increased by 8% (both P capacity to absorb new patients was limited. During a period in which southern California population grew by 8.5%, acute care beds fell by 3.3%, while Los Angeles County emergency departments experienced a 13% diversion rate due to overcrowding. Local or regional disasters of any size can overwhelm the system's ability to respond. Our strategy produced a surge capacity of 36% without interruption of emergency department and trauma services but required 3 to 4 days for implementation, making it applicable to disasters and mass casualty events with longer lead times. These principles may aid in disaster preparedness and planning.

  3. How do NHS organisations plan research capacity development? Strategies, strengths, and opportunities for improvement.

    Gee, Melanie; Cooke, Jo

    2018-03-22

    Research that is integral into a 'learning healthcare system' can promote cost effective services and knowledge creation. As such, research is defined as a 'core function' in UK health service organisations, and is often planned through research and development (R&D) strategies that aim to promote research activity and research capacity development (RCD). The discussion focuses around the content of ten R&D strategies for healthcare organisations in England and Scotland, with respect to RCD. These organisations were engaged with a research interest network called ACORN (Addressing Organisational Capacity to do Research Network) that included two Scottish Health Boards, four community and mental health trusts, two provincial district hospitals, and two teaching hospitals. We undertook a thematic documentary analysis of the R&D strategies which identified 11 'core activities' of RCD. The potential for building research capacity in these 'core activities' was established by reviewing them through the lens of a RCD framework. Core activities aimed to 'hard wire' RCD into health organisations. They demonstrated a complex interplay between developing a strong internal organisational infrastructure, and supporting individual career planning and skills development, in turn enabled by organisational processes. They also included activities to build stronger inter-organisational relationships and networks. Practitioner, manager and patient involvement was a cross cutting theme. The potential to demonstrate progress was included in plans through monitoring activity across all RCD principles. Strategies were primarily aimed at research production rather than research use. Developing 'actionable dissemination' was poorly addressed in the strategies, and represents an area for improvement. We describe strengths of RCD planning activities, and opportunities for improvement. We explore how national policy and research funders can influence health systems' engagement in research.

  4. Evaluating the Cost of Line Capacity Limitations in Aggregations of Commercial Buildings

    Ziras, Charalampos; Delikaraoglou, Stefanos; Kazempour, Jalal

    2017-01-01

    -ahead optimization strategy to assess the cost of imposing capacity limitations in the total consumption of individual buildings, as well as aggregations of buildings. We show that such capacity limitations lead to an increase for the buildings operational costs, which can be interpreted as the value...... of these limitations. Based on such calculations, the aggregator can value capacity-limitation services to the distribution system operator. Moreover, the value of aggregation is also highlighted, since it leads to lower costs than imposing the same total capacity limitation on individual buildings....

  5. Using discrete-event simulation in strategic capacity planning for an outpatient physical therapy service.

    Rau, Chi-Lun; Tsai, Pei-Fang Jennifer; Liang, Sheau-Farn Max; Tan, Jhih-Cian; Syu, Hong-Cheng; Jheng, Yue-Ling; Ciou, Ting-Syuan; Jaw, Fu-Shan

    2013-12-01

    This study uses a simulation model as a tool for strategic capacity planning for an outpatient physical therapy clinic in Taipei, Taiwan. The clinic provides a wide range of physical treatments, with 6 full-time therapists in each session. We constructed a discrete-event simulation model to study the dynamics of patient mixes with realistic treatment plans, and to estimate the practical capacity of the physical therapy room. The changes in time-related and space-related performance measurements were used to evaluate the impact of various strategies on the capacity of the clinic. The simulation results confirmed that the clinic is extremely patient-oriented, with a bottleneck occurring at the traction units for Intermittent Pelvic Traction (IPT), with usage at 58.9 %. Sensitivity analysis showed that attending to more patients would significantly increase the number of patients staying for overtime sessions. We found that pooling the therapists produced beneficial results. The average waiting time per patient could be reduced by 45 % when we pooled 2 therapists. We found that treating up to 12 new patients per session had no significantly negative impact on returning patients. Moreover, we found that the average waiting time for new patients decreased if they were given priority over returning patients when called by the therapists.

  6. Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines.

    Al-Ashaal, Hanan A; El-Sheltawy, Shakinaz T

    2011-03-01

    Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities. The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicity against different human carcinoma cell lines. In the present work, hesperidin is identified and confirmed using chromatographic and spectral analysis. To correlate between hesperidin concentration and antioxidant capacity of peel extracts, extraction was carried out using 1% HCl-MeOH, MeOH, alkaline solution, the concentration of hesperidin determined qualitatively and quantitatively using high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC) analysis, in vitro antioxidant capacity of hesperidin and the extracts against free radical diphenylpicrylhydrazyl (DPPH•) performed using an electron spin resonance spectrophotometer (ESR). Cytotoxic assay against larynx, cervix, breast and liver carcinoma cell lines was performed. Hesperidin was found to be moderately active as an antioxidant agent; its capacity reached 36%. In addition, the results revealed that hesperidin exhibited pronounced anticancer activity against the selected cell lines. IC₅₀ were 1.67, 3.33, 4.17, 4.58 µg/mL, respectively. Orange peels are considered to be a cheap source for hesperidin which may be used in the pharmaceutical industry as a natural chemopreventive agent. Hesperidin and orange peel extract could possess antioxidant properties with a wide range of therapeutic applications.

  7. Electric sector capacity planning under uncertainty: Climate policy and natural gas in the US

    Bistline, John E.

    2015-01-01

    This research investigates the dynamics of capacity planning and dispatch in the US electric power sector under a range of technological, economic, and policy-related uncertainties. Using a two-stage stochastic programming approach, model results suggest that the two most critical risks in the near-term planning process of the uncertainties considered here are natural gas prices and the stringency of climate policy. Stochastic strategies indicate that some near-term hedging from lower-cost wind and nuclear may occur but robustly demonstrate that delaying investment and waiting for more information can be optimal to avoid stranding capital-intensive assets. Hedging strategies protect against downside losses while retaining the option value of deferring irreversible commitments until more information is available about potentially lucrative market opportunities. These results are explained in terms of the optionality of investments in the electric power sector, leading to more general insights about uncertainty, learning, and irreversibility. The stochastic solution is especially valuable if decision-makers do not sufficiently account for the potential of climate constraints in future decades or if fuel price projections are outdated. - Highlights: • Explicitly incorporating uncertainty influences capacity planning decisions. • Natural gas prices and climate policy are the two most critical risks for utilities. • Strategic delay can be explained in terms of real options. • Stochastic strategies are especially valuable when outdated assumptions are used.

  8. Capacity planning of a wide-sense nonblocking generalized survivable network

    Ho, Kwok Shing; Cheung, Kwok Wai

    2006-06-01

    Generalized survivable networks (GSNs) have two interesting properties that are essential attributes for future backbone networks--full survivability against link failures and support for dynamic traffic demands. GSNs incorporate the nonblocking network concept into the survivable network models. Given a set of nodes and a topology that is at least two-edge connected, a certain minimum capacity is required for each edge to form a GSN. The edge capacity is bounded because each node has an input-output capacity limit that serves as a constraint for any allowable traffic demand matrix. The GSN capacity planning problem is nondeterministic polynomial time (NP) hard. We first give a rigorous mathematical framework; then we offer two different solution approaches. The two-phase approach is fast, but the joint optimization approach yields a better bound. We carried out numerical computations for eight networks with different topologies and found that the cost of a GSN is only a fraction (from 52% to 89%) more than that of a static survivable network.

  9. Scenario calculations for the 2012 grid development plan. Overdimensioned HVDC transmission lines; Szenarienrechnungen zum Netzentwicklungsplan (NEP) 2012. HGUe-Leitungen ueberdimensioniert

    Oei, Pao-Yu; Sander, Aram; Hankel, Lisa; Laurisch, Lilian; Lorenz, Casimir [Technische Univ. Berlin (Germany); Schroeder, Andreas [Deutsches Institut fuer Wirtschaftsforschung, Berlin (Germany)

    2012-09-15

    The grid development plan presented in June 2012 by the German Federal Network Agency envisages a large number of new AC and DC transmission lines for Germany. The purpose of these transmission lines is to facilitate the point-to-point transport of electricity produced from renewable resources to load centres. The authors present a model-assisted analysis of the impact of these transmission lines on the structure of electricity production. They also investigate to what extent an increase in storage capacity and the steering of demand can serve as alternatives to grid expansion.

  10. Transportation tolls, services and capacity : report from TransCanada PipeLines Limited on its changing mainline system

    McPherson, J.

    2003-01-01

    This presentation described the measures that TransCanada PipeLines Limited has taken to change its business model while lowering operating costs. The company is concerned about keeping tolls as low as possible to maintain competitiveness. Demand for pipeline capacity over the next five years is expected to be as high as 1.0 Bcf. Incremental capacity will be required to serve the markets. The market drivers for transportation were described as being reliability, greater price certainty, optionality, and stability in terms of contracts, service and regulations. 1 fig

  11. Capacity Planning for Batch and Perfusion Bioprocesses Across Multiple Biopharmaceutical Facilities

    Siganporia, Cyrus C; Ghosh, Soumitra; Daszkowski, Thomas; Papageorgiou, Lazaros G; Farid, Suzanne S

    2014-01-01

    Production planning for biopharmaceutical portfolios becomes more complex when products switch between fed-batch and continuous perfusion culture processes. This article describes the development of a discrete-time mixed integer linear programming (MILP) model to optimize capacity plans for multiple biopharmaceutical products, with either batch or perfusion bioprocesses, across multiple facilities to meet quarterly demands. The model comprised specific features to account for products with fed-batch or perfusion culture processes such as sequence-dependent changeover times, continuous culture constraints, and decoupled upstream and downstream operations that permit independent scheduling of each. Strategic inventory levels were accounted for by applying cost penalties when they were not met. A rolling time horizon methodology was utilized in conjunction with the MILP model and was shown to obtain solutions with greater optimality in less computational time than the full-scale model. The model was applied to an industrial case study to illustrate how the framework aids decisions regarding outsourcing capacity to third party manufacturers or building new facilities. The impact of variations on key parameters such as demand or titres on the optimal production plans and costs was captured. The analysis identified the critical ratio of in-house to contract manufacturing organization (CMO) manufacturing costs that led the optimization results to favor building a future facility over using a CMO. The tool predicted that if titres were higher than expected then the optimal solution would allocate more production to in-house facilities, where manufacturing costs were lower. Utilization graphs indicated when capacity expansion should be considered. © 2013 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers Biotechnol. Prog., 30:594–606, 2014 PMID:24376262

  12. Capacity planning for batch and perfusion bioprocesses across multiple biopharmaceutical facilities.

    Siganporia, Cyrus C; Ghosh, Soumitra; Daszkowski, Thomas; Papageorgiou, Lazaros G; Farid, Suzanne S

    2014-01-01

    Production planning for biopharmaceutical portfolios becomes more complex when products switch between fed-batch and continuous perfusion culture processes. This article describes the development of a discrete-time mixed integer linear programming (MILP) model to optimize capacity plans for multiple biopharmaceutical products, with either batch or perfusion bioprocesses, across multiple facilities to meet quarterly demands. The model comprised specific features to account for products with fed-batch or perfusion culture processes such as sequence-dependent changeover times, continuous culture constraints, and decoupled upstream and downstream operations that permit independent scheduling of each. Strategic inventory levels were accounted for by applying cost penalties when they were not met. A rolling time horizon methodology was utilized in conjunction with the MILP model and was shown to obtain solutions with greater optimality in less computational time than the full-scale model. The model was applied to an industrial case study to illustrate how the framework aids decisions regarding outsourcing capacity to third party manufacturers or building new facilities. The impact of variations on key parameters such as demand or titres on the optimal production plans and costs was captured. The analysis identified the critical ratio of in-house to contract manufacturing organization (CMO) manufacturing costs that led the optimization results to favor building a future facility over using a CMO. The tool predicted that if titres were higher than expected then the optimal solution would allocate more production to in-house facilities, where manufacturing costs were lower. Utilization graphs indicated when capacity expansion should be considered. © 2014 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers.

  13. Planning the most suitable travel speed for high frequency railway lines

    Landex, Alex; Kaas, Anders H.

    2005-01-01

    the interlocking system. Based on the braking distance it is possible to calculate the minimum headway time, and thereby determine the buffer time when knowing the frequency. Hence the headway time can be divided into minimum headway time and buffer time. The buffer time is an indicator for the spare capacity......This paper presents a new method to calculate the most suitable travel speed for high frequency railway lines to achieve as much capacity as possible for congested railway lines. The method calculates the most suitable travel speed based on the braking distance and information about...

  14. Marketing plan for Pharmacare product line in the Moscow region Case Oriola-KD

    Mashkilleyson, Peter

    2012-01-01

    The thesis was commissioned by Oriola-KD. It deals with a marketing plan for a product line called Pharmacare. The product line will be launched in 2012 in the Moscow region in the Russian Federation. The purpose of this thesis was to acquire useful information about the Moscow market for the target company and produce a marketing plan that they can implement. The research question was how to create an effective marketing plan and what it entails. The literary review consisted of the theo...

  15. Study plan for evaluating carrying capacity: Measure 7.1A of the Northwest Power Planning Council's 1994 Fish and Wildlife Program. Report 2 of 4, Final report

    Neitzel, D.A.; Johnson, G.E.

    1996-05-01

    This report is one report of four that the Pacific Northwest National Laboratory (PNNL) staff used to address Measure 7.1A in the Northwest Power Planning Council's (Council) fish and Wildlife Program (Program) dated December 1994 (NPPC 1994). Measure 7.1A calls for the Bonneville Power Administration (BPA) to fund an evaluation of salmon survival, ecology, carrying capacity, and limiting factors in freshwater, estuarine, and marine habitats. Additionally, the Measure asks for the development of a study plan based on the critical uncertainties and research needs identified during the evaluation. In the evaluation of carrying capacity the authors concluded that defining capacity and listing the determinants of capacity is not a simple exercise. Capacity is a complex variable among the attributes that all together define salmon performance. To pursue the capacity parameter, that is, a single number or set of numbers that quantify how many salmon the basin or any part of the basin can support, will not lead to the development of a useful study plan. To increase understanding of ecology, carrying capacity, and limiting factors, it is necessary to deal with the complexity of the sustained performance of salmon in the Columbia River Basin. This report describes the elements of a study plan that could be used to increase the understanding of ecology, carrying capacity, and limiting factors that influence salmon survival under current conditions

  16. Planning Electric Transmission Lines: A Review of Recent Regional Transmission Plans

    Eto, Joseph H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-04-13

    The first Quadrennial Energy Review (QER) recommends that the U.S. Department of Energy (DOE) conduct a national review of transmission plans and assess the barriers and incentives to their implementation. DOE tasked Lawrence Berkeley National Laboratory (LBNL) to prepare two reports to support the agency’s response to this recommendation. This report reviews regional transmission plans and regional transmission planning processes that have been directed by Federal Energy Regulatory Commission (FERC) Order Nos. 890 and 1000. We focus on the most recent regional transmission plans (those issued in 2015 and through approximately mid-year 2016) and current regional transmission planning processes. A companion report focuses on non-plan-related factors that affect transmission projects.

  17. Huge natural gas reserves central to capacity work, construction plans in Iran

    Anon.

    1994-01-01

    Questions about oil production capacity in Iran tend to mask the country's huge potential as a producer of natural gas. Iran is second only to Russia in gas reserves, which National Iranian Gas Co. estimates at 20.7 trillion cu m. Among hurdles to Iran's making greater use of its rich endowment of natural gas are where and how to sell gas not used inside the country. The marketing logistics problem is common to other Middle East holders of gas reserves and a reason behind the recent proliferation of proposals for pipeline and liquefied natural gas schemes targeting Europe and India. But Iran's challenges are greater than most in the region. Political uncertainties and Islamic rules complicate long-term financing of transportation projects and raise questions about security of supply. As a result, Iran has remained mostly in the background of discussions about international trade of Middle Eastern gas. The country's huge gas reserves, strategic location, and existing transport infrastructure nevertheless give it the potential to be a major gas trader if the other issues can be resolved. The paper discusses oil capacity plans, gas development, gas injection for enhanced oil recovery, proposals for exports of gas, and gas pipeline plans

  18. The Effects of Pre-Task Planning and On-line Planning on Fluency, Complexity, and Accuracy in L2 Monologic Oral Production.

    Yuan, Fangyuan; Ellis, Rod

    2003-01-01

    Investigated the effects of both pre-task and on-line planning on second language (L2) oral production. Results show that pre-task planning enhances grammatical complexity while on-line planning positively influences accuracy and grammatical complexity. Pre-task planners also produced more fluent and lexically varied language than the on-line…

  19. Implementation plan for the new production reactor capacity environmental impact statement

    1989-12-01

    The US Department of Energy (DOE) proposed to site, construct, and operate new production reactor (NPR) capacity intended primarily to produce tritium and secondarily to produce plutonium for the US nuclear weapons program. DOE studies show that this new capacity is needed to ensure reliable maintenance of the nation's nuclear weapons stockpile. It also is essential that these necessary nuclear materials be produced in a safe and environmentally sound manner. The DOE has determined that this proposed action constitutes a major federal action that may significantly affect the quality of the human environment; therefore, the DOE will prepare an environmental impact statement (EIS) to assess the potential impacts of the proposed action and reasonable alternatives on the human and natural environment. The EIS will be prepared in accordance with the National Environmental Policy Act of 1969, as implemented in regulations promulgated by the Council on Environmental Quality (CEQ). This EIS implementation plan (IP) includes a description of the proposed action, descriptions of alternatives, a summary of EIS assumptions, a list of environmental issues to be considered in the EIS (including those identified during public scoping activities), a list of proposed agency consultations, a schedule for EIS preparation and related activities, and an annotated outline for the EIS. It is the Department's intent that the EIS on the NPR capacity will serve as the programmatic National Environmental Policy Act (NEPA) review of modernization of DOE defense nuclear materials production of tritium and plutonium. The Department is currently developing a NEPA compliance strategy for modernization of the remainder of the nuclear weapons production complex, which will reference the EIS on NPR capacity. 7 refs., 8 tabs

  20. Capacity planning of link restorable optical networks under dynamic change of traffic

    Ho, Kwok Shing; Cheung, Kwok Wai

    2005-11-01

    Future backbone networks shall require full-survivability and support dynamic changes of traffic demands. The Generalized Survivable Networks (GSN) was proposed to meet these challenges. GSN is fully-survivable under dynamic traffic demand changes, so it offers a practical and guaranteed characterization framework for ASTN / ASON survivable network planning and bandwidth-on-demand resource allocation 4. The basic idea of GSN is to incorporate the non-blocking network concept into the survivable network models. In GSN, each network node must specify its I/O capacity bound which is taken as constraints for any allowable traffic demand matrix. In this paper, we consider the following generic GSN network design problem: Given the I/O bounds of each network node, find a routing scheme (and the corresponding rerouting scheme under failure) and the link capacity assignment (both working and spare) which minimize the cost, such that any traffic matrix consistent with the given I/O bounds can be feasibly routed and it is single-fault tolerant under the link restoration scheme. We first show how the initial, infeasible formal mixed integer programming formulation can be transformed into a more feasible problem using the duality transformation of the linear program. Then we show how the problem can be simplified using the Lagrangian Relaxation approach. Previous work has outlined a two-phase approach for solving this problem where the first phase optimizes the working capacity assignment and the second phase optimizes the spare capacity assignment. In this paper, we present a jointly optimized framework for dimensioning the survivable optical network with the GSN model. Experiment results show that the jointly optimized GSN can bring about on average of 3.8% cost savings when compared with the separate, two-phase approach. Finally, we perform a cost comparison and show that GSN can be deployed with a reasonable cost.

  1. Layout Design for a Low Capacity Manufacturing Line: A Case Study

    De Carlo, Filippo; Arleo, Maria Antonietta; Borgia, Orlando; Tucci, Mario

    2013-01-01

    The layout re‐arrangement of fashion production lines realizing many small batches is rarely deployed according to well‐known engineering procedures. In fact, it would often appear too complex to call a plant engineer for the proper layout design of such small production lines. Rather, it is preferred to apply empirical methodologies when considering, generally, factory know‐how, general business needs, safety requirements, and so on. In the present work, the results of a fashion manufacturin...

  2. A Production Planning Model for Make-to-Order Foundry Flow Shop with Capacity Constraint

    Xixing Li

    2017-01-01

    Full Text Available The mode of production in the modern manufacturing enterprise mainly prefers to MTO (Make-to-Order; how to reasonably arrange the production plan has become a very common and urgent problem for enterprises’ managers to improve inner production reformation in the competitive market environment. In this paper, a mathematical model of production planning is proposed to maximize the profit with capacity constraint. Four kinds of cost factors (material cost, process cost, delay cost, and facility occupy cost are considered in the proposed model. Different factors not only result in different profit but also result in different satisfaction degrees of customers. Particularly, the delay cost and facility occupy cost cannot reach the minimum at the same time; the two objectives are interactional. This paper presents a mathematical model based on the actual production process of a foundry flow shop. An improved genetic algorithm (IGA is proposed to solve the biobjective problem of the model. Also, the gene encoding and decoding, the definition of fitness function, and genetic operators have been illustrated. In addition, the proposed algorithm is used to solve the production planning problem of a foundry flow shop in a casting enterprise. And comparisons with other recently published algorithms show the efficiency and effectiveness of the proposed algorithm.

  3. Comparative miRNAs analysis of Two contrasting broccoli inbred lines with divergent head-forming capacity under temperature stress.

    Chen, Chi-Chien; Fu, Shih-Feng; Norikazu, Monma; Yang, Yau-Wen; Liu, Yu-Ju; Ikeo, Kazuho; Gojobori, Takashi; Huang, Hao-Jen

    2015-12-01

    MicroRNAs (miRNAs) play a vital role in growth, development, and stress response at the post-transcriptional level. Broccoli (Brassica oleracea L. var italic) is an important vegetable crop, and the yield and quality of broccoli are decreased by heat stress. The broccoli inbred lines that are capable of producing head at high temperature in summer are unique varieties in Taiwan. However, knowledge of miRNAomes during the broccoli head formation under heat stress is limited. In this study, molecular characterization of two nearly isogenic lines with contrasting head-forming capacity was investigated. Head-forming capacity was better for heat-tolerant (HT) than heat-sensitive (HS) broccoli under heat stress. By deep sequencing and computational analysis, 20 known miRNAs showed significant differential expression between HT and HS genotypes. According to the criteria for annotation of new miRNAs, 24 novel miRNA sequences with differential expression between the two genotypes were identified. To gain insight into functional significance, 213 unique potential targets of these 44 differentially expressed miRNAs were predicted. These targets were implicated in shoot apical development, phase change, response to temperature stimulus, hormone and energy metabolism. The head-forming capacity of the unique HT line was related to autonomous regulation of Bo-FT genes and less expression level of heat shock protein genes as compared to HS. For the genotypic comparison, a set of miRNAs and their targets had consistent expression patterns in various HT genotypes. This large-scale characterization of broccoli miRNAs and their potential targets is to unravel the regulatory roles of miRNAs underlying heat-tolerant head-forming capacity.

  4. A Case Study of Line-of-Balance based Schedule Planning and Control System

    Seppänen, Olli; Aalto, Erno

    2005-01-01

    Line-of-Balance is a graphical technique which can be used to plan and manage work flow. It is suit-able for construction projects because of their large degree of repetition. Despite its strengths Line-of-Balance has not gained widespread use in construction industry internationally. However, it has been used as the principal scheduling tool in Finland since 1980s. As a result of two decades of research and use in industry, a comprehensive schedule planning and control system has been develo...

  5. The Planning of Straight Line Trajectory in Robotics Using Interactive Graphics

    Kesheng Wang

    1987-07-01

    Full Text Available The planning of straight line trajectory using the interactive computer graphics simulation of robot manipulator movement is discussed. This new approach to straight line motion planning improves the 'bound deviation joint paths' developed by R. M. Taylor (1979. The new approach has three characteristics: (1 linear interpolation in joint space; (2 unequal intervals for interpolating knot points; (3 using interactive computer graphics to assure that the maximum deviation in the whole segment is less than the pre-specified values. The structure and mathematical basis of a computer program developed for this purpose are presented.

  6. Environmental impacts of power plants and transmission lines in power system planning

    Miracapillo, C.; Moreschini, G.; Rome Univ. 'La Sapienza'

    1992-01-01

    This paper deals with a criterion to assess the environmental impacts of power plants and transmission lines in power system planning. First, the effects of hydro-plants, thermal plants and transmission lines are reviewed. Then, a number of methods for the evaluation of the environmental impacts of civil and industrial plants are described. A new criterion is proposed to introduce the evaluation of the environmental impact and related costs into methods for power system planning. Finally, the criterion is applied to a simple case

  7. Resource Planning in Glaucoma: A Tool to Evaluate Glaucoma Service Capacity.

    Batra, Ruchika; Sharma, Hannah E; Elaraoud, Ibrahim; Mohamed, Shabbir

    2017-12-28

    The National Patient Safety Agency (2009) publication advising timely follow-up of patients with established glaucoma followed several reported instances of visual loss due to postponed appointments and patients lost to follow-up. The Royal College of Ophthalmologists Quality Standards Development Group stated that all hospital appointments should occur within 15% of the intended follow-up period. To determine whether: 1. Glaucoma follow-up appointments at a teaching hospital occur within the requested time 2. Appointments are requested at appropriate intervals based on the NICE Guidelines 3. The capacity of the glaucoma service is adequate Methods: A two-part audit was undertaken of 98 and 99 consecutive patients respectively attending specialist glaucoma clinics. In the first part, the reasons for delayed appointments were recorded. In the second part the requested follow-up was compared with NICE guidelines where applicable. Based on the findings, changes were implemented and a re-audit of 100 patients was carried out. The initial audit found that although clinical decisions regarding follow-up intervals were 100% compliant with NICE guidelines where applicable, 24% of appointments were delayed beyond 15% of the requested period, due to administrative errors and inadequate capacity, leading to significant clinical deterioration in two patients. Following the introduction of an electronic appointment tracker and increased clinical capacity created by extra clinics and clinicians, the re-audit found a marked decrease in the percentage of appointments being delayed (9%). This audit is a useful tool to evaluate glaucoma service provision, assist in resource planning for the service and bring about change in a non-confrontational way. It can be widely applied and adapted for use in other medical specialities.

  8. Incorporating environmental externalities into the capacity expansion planning: An Israeli case study

    Becker, Nir; Soloveitchik, David; Olshansky, Moshe

    2011-01-01

    Highlights: → Long term energy-environmental planning problems for the electricity sector. → Environmental considerations in the capacity expansion plan. → Modified version of WASP-IV as a multiple objective programming model. → Multi-objective analysis of trade-offs between costs and pollutants reduction. -- Abstract: In this paper we use the WASP-IV model and develop methodology to estimate the impact of several environmental externality costs on the electricity sector development plan. For this purpose, 22 cases were generated which were later on reduced to only seven non-dominated cases by considering this problem as a dynamic multiple objective programming model. The major impact of internalizing the external cost is on fuel use. In the electricity generation system more natural gas and less coal has been used. A cost benefit analysis (CBA) of three scenarios has been performed focusing on taxing only one pollutant while looking at its overall implication. The benefit cost ratio was about 4.5 while the net benefit was about 200 million USD (depending on the scenario). Multi-objective analysis among the different scenarios was carried in a dynamic setting. Seven scenarios appear in the non-dominated set. Out of them five appears in every year and those should have a higher weight placed on them by policy makers. Out of those five, two are a single tax on one pollutant. Thus, policy makers might want to consider a mixture of taxes but for the sake of simplicity can also use a simple one tax on a given pollutant.

  9. Implementation of Capacity Planning Agent of Demand Responsive Planning Framework : Master’s Thesis in Production Engineering of The Royal Institute of Technology

    Juhong, Nirut

    2013-01-01

    This master’s thesis is conducted as a conclusion of Master degree of Science in Production Engineering and Management at The Royal Institute of Technology. The focus of this thesis work is to implement a Capacity planning agent. Nowadays, companies need to adapt themselves to be as responsive to customers’ demand as possible. However, the responsiveness is usually limited by the fixed capacity of the production. Evolvable Production System (EPS), motivated by the limitation mentioned above, ...

  10. Coupling and corona effects research plan for transmission lines. Final report

    Bridges, J E; Formanek, V C

    1976-06-01

    Concern has arisen over the possible effects of electric and magnetic fields produced by EHV-UHV transmission lines. Past and ongoing research concerning the electric and magnetic field effects from EHV-UHV transmission lines was reviewed as it pertains to the following areas: (1) electromagnetic interference, (2) acoustic noise, (3) generation of gaseous effluents, and (4) safety considerations of induced voltages and currents. The intent of this review was to identify the short and long range research projects required to address these areas. The research plan identifies and gives priority to twenty programs in corona and coupling effects. In the case of the corona effects, a number of programs were recommended for acoustic noise and electromagnetic interference to delineate improved power line design criteria in terms of social, meteorological, geographical and cost constraints. Only one project is recommended in the case of ozone generation, because the results of comprehensive analyses, laboratory studies and field measurements have demonstrated that power lines do not contribute significant quantities of ozone. In the case of the coupling effects, a number of programs are recommended for HVAC transmission lines to improve the theoretically developed design guidelines by considering practical constraints. For HVDC transmission lines, programs are suggested to engender a better theoretical understanding and practical measurements capability for the coupling mechanisms of the dc electric and magnetic field with nearby objects. The interrelationship of the programs and their role in a long-term research plan is also discussed.

  11. Line Capacity Expansion and Transmission Switching in Power Systems With Large-Scale Wind Power

    Villumsen, Jonas Christoffer; Bronmo, Geir; Philpott, Andy B.

    2013-01-01

    In 2020 electricity production from wind power should constitute nearly 50% of electricity demand in Denmark. In this paper we look at optimal expansion of the transmission network in order to integrate 50% wind power in the system, while minimizing total fixed investment cost and expected cost...... of power generation. We allow for active switching of transmission elements to reduce congestion effects caused by Kirchhoff's voltage law. Results show that actively switching transmission lines may yield a better utilization of transmission networks with large-scale wind power and increase wind power...

  12. Where spatial capacity building and spatial decision making meet. Publically debating participatory spatial planning via a newspaper.

    Huybrechts, Liesbeth; Martens, Sarah; Devisch, Oswald

    2015-01-01

    This article reports on the in-between results of a Participatory Design research process in spatial planning in Godsheide, a small village in the Belgian Region of Limburg. The research explores how the language of newspapers enables citizens, policy makers, property developers and local organisations to build capacities (cfr. spatial capacity building) in ‘scripting’ their reflections on, but also actions in spatial change. In the heads of our participants, there existed a duality between -...

  13. ENVIRONMENTAL CARRYING CAPACITY BASED ON LAND BALANCE FOR EVALUATION PLANNING OF SPATIAL AND REGIONAL IN SOLOK REGENCY, WEST SUMATRA

    Alvan Pahuluan

    2017-05-01

    Full Text Available Act No. 26 of 2007 on Spatial Planning stated that the central and the local government should establish Spatial and Regional Planning (RTRW by considering environmental carrying capacity. The environmental carrying capacity based RTRW will ensure the balance between the use of natural resources and the prevention of negative impacts on the environment. The objective of this study was to evaluate the implementation of RTRW at Solok Regency Year 2012 - 2031 which has been established in 2013. Evaluation was conducted by calculating land carrying capacity method to determine land supply and land demand. The results showed that the land use planned as stated in the RTRW increase the land supply in supporting bio-product production to meet the needs of the population, with surplus conditions amounted to 101,005.79 hectares. The future predictions indicated that the carrying capacity of planned land could met the needs of the population bio-product until the year 2121. The evaluation of the spatial pattern plan showed that there was a need to increase the area of housing and settlements in accordance with the rate of population increase and determine the extents area for the development of the livestock sector to improve its yield.

  14. Graded Approach to the Development of a Contingency Plan for On-Line Maintenance

    Chang, Hee Seung; Kim, Jung Wun; Song, Tae Young

    2012-01-01

    Many utilities perform preventive maintenance for safety systems during power operation to improve equipment reliability so as to focus on the work activities more easily and improve the quality of maintenance. Such a strategy can also reduce outage work activities, thus allowing resources to be utilized effectively. Preventive maintenance during power operation, known as on-line maintenance (OLM), requires an assessment and mitigation of risk, which can increase owing to out-of-service safety systems. One of the mitigation action plans is a contingency plan. EPRI recommends the development of a contingency plan for all planned system outages which include factors that strongly affect safety. The Korea Hydro and Nuclear Power Company (KHNP) undertook the preventive maintenance of the Essential Chilled Water System (ECWS) of a Westinghouse plant as a pilot OLM implementation. During the preparation of the work activities, a contingency plan was a pertinent issue during the discussions with regulators, especially regarding the scope and depth of the plan. This paper discusses the purpose of a contingency plan, including as examples some cases of US utilities, and proposes a graded approach to develop a contingency plan for OLM in consideration of the risks

  15. A capacity expansion planning model for integrated water desalination and power supply chain problem

    Saif, Y.; Almansoori, A.

    2016-01-01

    Highlights: • Water and power supply chain is considered by a discrete optimization model. • The model examines the capacity expansion and operation of the supply chain problem. • Renewable/alternative power technologies and carbon mitigation are considered. • A case study of Abu Dhabi in UAE is examined as an application of the model. - Abstract: Cogeneration of water and power in integrated cogeneration production plants is a common practice in the Middle East and North Africa (MENA) countries. There are several combinations of water desalination and power technologies which give significant adverse environmental impact. Renewable and alternative energy technologies have been recently proposed as alternative power production paths in the water and power sector. In this study, we examine the optimal capacity expansion of water and power infrastructure over an extended planning horizon. A generic mixed integer linear programming model is developed to assist in the decision making process on: (1) optimal installation of cogeneration expansion capacities; (2) optimal installation of renewable and alternative power plants; (3) optimal operation of the integrated water and power supply chain over large geographical areas. Furthermore, the model considers the installation of carbon capture methods in fossil-based power plants. A case study will be presented to illustrate the mathematical programming application for the Emirate of Abu Dhabi (AD) in the United Arab Emirates (UAE). The case study is solved reflecting different scenarios: base case scenario, integration of renewable and alternative technologies scenario, and CO_2 reduction targets scenario. The results show that increased carbon tax values up to 150 $/ton-CO_2 gives a maximum 3% cost increase for the supply chain net present value. The installation of carbon capture methods is not an economical solution due to its high operation energy requirements in the order of 370 kW h per ton of captured CO_2

  16. Antiproliferative activity in tumor cell lines, antioxidant capacity and total phenolic, flavonoid and tannin contents of Myrciaria floribunda

    LUIS A.C. TIETBOHL

    Full Text Available ABSTRACT Myrciaria floribunda (H. West ex Willd. O. Berg, Myrtaceae, is a native plant species of the Atlantic Rain Forest, from north to south of Brazil. The lyophilized ethyl acetate extract from the leaves of M. floribunda was investigated for its antiproliferative activity in tumor cell lines, antioxidant capacity and its total phenolic, flavonoid and tannin contents. Antiproliferative activity was tested in vitro against seven human cancer cells and against immortalized human skin keratinocytes line (HaCat, no cancer cell. Antioxidant activity was determined using 1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging and oxygen radical absorbing capacity (ORAC assays and total phenolic, flavonoid and tannin contents were determined by spectrophotometric techniques. Ethyl acetate extract of M. floribunda exhibited antiproliferative activity against cancer cell lines with total growth inhibition (TGI between 69.70 and 172.10 µg/mL. For HaCat cell, TGI value was 213.60 µg/mL. M. floribunda showed a strong antioxidant potential: EC50 of 45.89±0.42 µg/mL and 0.55±0.05 mmol TE/g for DPPH and ORAC, respectively. Total phenolic content was 0.23±0.013g gallic acid equivalents (GAE/g extract and exhibited 13.10±1.60% of tannins content. The content of flavonoid was 24.08±0.44% expressed as rutin equivalents. These results provide a direction for further researches about the antitumoral potential of M. floribunda.

  17. Efficient on-line setup correction strategies using plan-intent functions

    Keller, Harry; Jaffray, David A.; Rosewall, Tara; White, Elizabeth

    2006-01-01

    With the introduction of image-guided radiation therapy (IGRT) delivery systems on-line set-up correction strategies have gained in popularity. Usually, the correction workload of these strategies is high compared to off-line strategies as daily setup corrections have to be performed based on a predefined action level. In this work, it is proposed that on-line strategies must not only be judged in terms of workload but also in terms of efficacy. While workload can be easily predicted for such strategies, the efficacy must ultimately reflect the efficiency with which the original treatment plan intent is met. The purpose of this work is to investigate the tradeoff between workload and efficacy of three different on-line set-up correction strategies: The common fixed action level strategy and two novel on-line setup correction strategies, i.e., a dose-volume histogram (DVH) constraint and an equivalent uniform dose (EUD) score strategy that aim directly for better compliance with original treatment plan intent. All strategies were reformulated in terms of a score function that reflected treatment plan intent. A retrospective study was conducted on 5 prostate patients (7-field conformal, 79.8 Gy, 42 fractions). PTV margins were 10 mm except in the posterior direction (7 mm). The original treatment plan intent for these patients was defined using a set of DVH constraints. The results show that the on-line setup correction strategy based on a fixed action level of 3 mm resulted in a considerable correction workload. For larger action levels, a dose benefit (in terms of EUD) in the rectum and bladder was observed for all patients which is clinically ''fortuitous'' but difficult to take advantage of. In contrast, the application of the two novel strategies generally resulted in a controlled decrease of the dose to the rectum and the bladder with a smaller workload. It is concluded that using information about target anatomy and the planned dose distribution allows the

  18. MiR-34a regulates the invasive capacity of canine osteosarcoma cell lines.

    Cecilia M Lopez

    Full Text Available Osteosarcoma (OSA is the most common bone tumor in children and dogs; however, no substantial improvement in clinical outcome has occurred in either species over the past 30 years. MicroRNAs (miRNAs are small non-coding RNAs that regulate gene expression and play a fundamental role in cancer. The purpose of this study was to investigate the potential contribution of miR-34a loss to the biology of canine OSA, a well-established spontaneous model of the human disease.RT-qPCR demonstrated that miR-34a expression levels were significantly reduced in primary canine OSA tumors and canine OSA cell lines as compared to normal canine osteoblasts. In canine OSA cell lines stably transduced with empty vector or pre-miR-34a lentiviral constructs, overexpression of miR-34a inhibited cellular invasion and migration but had no effect on cell proliferation or cell cycle distribution. Transcriptional profiling of canine OSA8 cells possessing enforced miR-34a expression demonstrated dysregulation of numerous genes, including significant down-regulation of multiple putative targets of miR-34a. Moreover, gene ontology analysis of down-regulated miR-34a target genes showed enrichment of several biological processes related to cell invasion and motility. Lastly, we validated changes in miR-34a putative target gene expression, including decreased expression of KLF4, SEM3A, and VEGFA transcripts in canine OSA cells overexpressing miR-34a and identified KLF4 and VEGFA as direct target genes of miR-34a. Concordant with these data, primary canine OSA tumor tissues demonstrated increased expression levels of putative miR-34a target genes.These data demonstrate that miR-34a contributes to invasion and migration in canine OSA cells and suggest that loss of miR-34a may promote a pattern of gene expression contributing to the metastatic phenotype in canine OSA.

  19. MiR-34a regulates the invasive capacity of canine osteosarcoma cell lines.

    Lopez, Cecilia M; Yu, Peter Y; Zhang, Xiaoli; Yilmaz, Ayse Selen; London, Cheryl A; Fenger, Joelle M

    2018-01-01

    Osteosarcoma (OSA) is the most common bone tumor in children and dogs; however, no substantial improvement in clinical outcome has occurred in either species over the past 30 years. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and play a fundamental role in cancer. The purpose of this study was to investigate the potential contribution of miR-34a loss to the biology of canine OSA, a well-established spontaneous model of the human disease. RT-qPCR demonstrated that miR-34a expression levels were significantly reduced in primary canine OSA tumors and canine OSA cell lines as compared to normal canine osteoblasts. In canine OSA cell lines stably transduced with empty vector or pre-miR-34a lentiviral constructs, overexpression of miR-34a inhibited cellular invasion and migration but had no effect on cell proliferation or cell cycle distribution. Transcriptional profiling of canine OSA8 cells possessing enforced miR-34a expression demonstrated dysregulation of numerous genes, including significant down-regulation of multiple putative targets of miR-34a. Moreover, gene ontology analysis of down-regulated miR-34a target genes showed enrichment of several biological processes related to cell invasion and motility. Lastly, we validated changes in miR-34a putative target gene expression, including decreased expression of KLF4, SEM3A, and VEGFA transcripts in canine OSA cells overexpressing miR-34a and identified KLF4 and VEGFA as direct target genes of miR-34a. Concordant with these data, primary canine OSA tumor tissues demonstrated increased expression levels of putative miR-34a target genes. These data demonstrate that miR-34a contributes to invasion and migration in canine OSA cells and suggest that loss of miR-34a may promote a pattern of gene expression contributing to the metastatic phenotype in canine OSA.

  20. Probabilistic Analysis for Capacity Planning in Smart Grid at Residential Low Voltage Level by Monte-Carlo Method

    Du, W.

    2011-01-01

    Smart Grid integrates sustainable energy sources and allows mutual communications between electricity distribution operators and electricity consumers. Electricity demand and supply becomes more complex in Smart Grid. It is more challenging for DNOs in grid asset capacity planning, especially at low

  1. Building the Capacity of States to Ensure Inclusion of Rural Communities in State and Local Primary Violence Prevention Planning

    Cook-Craig, Patricia G.; Lane, Karen G.; Siebold, Wendi L.

    2010-01-01

    Rural, frontier, and geographically isolated communities face unique challenges associated with ensuring that they are equal partners in capacity-building and prevention planning processes at the state and local level despite barriers that can inhibit participation. By their nature, rural, frontier, and geographically isolated communities and…

  2. The Relationship between Working Memory Capacity and L2 Oral Performance under Task-Based Careful Online Planning Condition

    Ahmadian, Mohammad Javad

    2012-01-01

    The study reported in this article aimed to investigate the way working memory capacity (WMC) interacts with careful online planning--a task-based implementation variable--to affect second language (L2) speech production. This issue is important to teachers, because it delves into one of the possible task-based implementation variables and thus…

  3. Production layout improvement by using line balancing and Systematic Layout Planning (SLP) at PT. XYZ

    Buchari; Tarigan, U.; Ambarita, M. B.

    2018-02-01

    PT. XYZ is a wood processing company which produce semi-finished wood with production system is make to order. In the production process, it can be seen that the production line is not balanced. The imbalance of the production line is caused by the difference in cycle time between work stations. In addition, there are other issues, namely the existence of material flow pattern is irregular so it resulted in the backtracking and displacement distance away. This study aimed to obtain the allocation of work elements to specific work stations and propose an improvement of the production layout based on the result of improvements in the line balancing. The method used in the balancing is Ranked Positional Weight (RPW) or also known as Helgeson Birnie method. While the methods used in the improvement of the layout is the method of Systematic Layout Planning (SLP). By using Ranked Positional Weight (RPW) obtained increase in line efficiency becomes 84,86% and decreased balance delay becomes 15,14%. Repairing the layout using the method of Systematic Layout Planning (SLP) also give good results with a reduction in path length becomes 133,82 meters from 213,09 meters previously or a decrease of 37.2%.

  4. Survival, growth performance and immune capacity of the juvenile lined seahorse Hippocampus erectus fed with rifampicin-treated copepods.

    Lin, Tingting; Wang, Changbo; Liu, Xin; Gao, Fen; Xiao, Dongxue; Zhang, Dong; Zhu, Xialian

    2017-06-19

    Gastrointestinal disease is one of the most serious diseases in cultured seahorse juveniles. Treatment with antimicrobials of live food (i.e. copepods and Artemia) that is used to feed the juveniles may be a promising measure to alleviate the occurrence of gastrointestinal disease. However, relevant investigations are rare. In the present study, we first investigated the antimicrobial efficacies on bacteria within copepods that were treated with 4 antimicrobials, including 3 antibiotics (i.e. enrofloxacin hydrochloride, oxytetracycline and rifampicin [RFP]) that are approved for use in aquaculture and 1 disinfectant (i.e. povidone iodine). We then assessed the effects of copepods treated with the antimicrobial that had the best antimicrobial efficacy on survival, growth performance and immune capacity of juvenile lined seahorses Hippocampus erectus. The results showed that RFP had the best antimicrobial efficacy on both Pseudoalteromonas spp. and Vibrio spp., 2 dominant bacteria with potential pathogenicity within the copepods; the proper concentration of RFP was 6 mg l-1. Moreover, H. erectus juveniles fed with RFP-treated copepods demonstrated an improved survivorship and immune capacity and had a lower abundance of pathogenic bacteria within their gastrointestinal tracts compared to juveniles fed with untreated copepods. These results suggest that treating live food with RFP is a potential measure for reducing the incidence of gastrointestinal disease in seahorse juveniles.

  5. Examining pre-service science teachers' developing pedagogical design capacity for planning and supporting task-based classroom discussions

    Ross, Danielle Kristina

    Teachers face many challenges as we move forward into the age of the Next Generation Science Standards (NGSS) (Achieve, Inc., 2013). The NGSS aim to develop a population of scientifically literate and talented students who can participate in the "innovation-driven economy" (p. 1). In order to meet these goals, teachers must provide students with opportunities to engage in science and engineering practices (SEPs) and learn core ideas of these disciplines. This study followed pre-service secondary science teachers as they participated in a secondary science teacher preparation program intended to support the development of their pedagogical design capacity (Brown, 2009) related to planning and supporting whole-class taskbased discussions. Teacher educators in this program designed an intervention that aimed in supporting this development. This study examined a particular dimension of PDC -- specifically, PSTs effective use of resources to plan science lessons in which students engage in a high demand task, participate in SEPs, and discuss their work in a whole-class setting. In order to examine the effectiveness of the intervention, I had to define PDC a priori. I measured PDC by documenting how/whether PSTs engaged in the following instructional planning practices: developing Learning Goals, selecting and/or designing challenging tasks, anticipating student thinking, planning for monitoring student thinking, imagining the discussion storyline, planning questions, and planning marking strategies. Analyses showed a significant difference between baseline lesson plan scores and Instructional Performance scores. These findings suggest these patterns and changes were directly linked to the teacher preparation program. The mean increase in Instructional Performance scores during the course of the teacher preparation year further supports the effect of the teacher preparation coursework. Pre-service teachers with high pedagogical design capacity continually integrated the

  6. An improved mechanism for capacity payment based on system dynamics modeling for investment planning in competitive electricity environment

    Assili, Mohsen; Javidi, D.B.; Hossein, M.; Ghazi, Reza

    2008-01-01

    Many countries have experienced restructuring in their electric utilities. This restructuring has presented the power industries with new challenges, the most important of which is long-term investment planning under uncertain conditions. This paper presents an improved mechanism for capacity payment. The mechanism has been investigated based on system dynamic modeling. In our proposed mechanism, generators will recover a part of their investment through capacity payment. While the payment for any plant remains constant during the operation period, it depends on the investment needed to build it. The main factors affecting long-term planning have been considered in our model. The approach can be used to investigate the effects of fixed as well as variable capacity payment in market investment. We used the probability density function of load as a new concept to calculate average market price. Delays in unit constructions, estimation of demand, and market capacity growth during construction periods have been included in the proposed algorithm as parameters, which affect the regulator's decision for changing capacity payment. The model can be used by regulators to investigate strategies that may affect the fluctuations in the market

  7. An improved mechanism for capacity payment based on system dynamics modeling for investment planning in competitive electricity environment

    Assili, Mohsen; Javidi DB, M. H.; Ghazi, Reza [Department of Electrical Engineering, Ferdowsi University of Mashhad, Mashhad (Iran)

    2008-10-15

    Many countries have experienced restructuring in their electric utilities. This restructuring has presented the power industries with new challenges, the most important of which is long-term investment planning under uncertain conditions. This paper presents an improved mechanism for capacity payment. The mechanism has been investigated based on system dynamic modeling. In our proposed mechanism, generators will recover a part of their investment through capacity payment. While the payment for any plant remains constant during the operation period, it depends on the investment needed to build it. The main factors affecting long-term planning have been considered in our model. The approach can be used to investigate the effects of fixed as well as variable capacity payment in market investment. We used the probability density function of load as a new concept to calculate average market price. Delays in unit constructions, estimation of demand, and market capacity growth during construction periods have been included in the proposed algorithm as parameters, which affect the regulator's decision for changing capacity payment. The model can be used by regulators to investigate strategies that may affect the fluctuations in the market. (author)

  8. Can Planning Time Compensate for Individual Differences in Working Memory Capacity?

    Nielson, Katharine B.

    2014-01-01

    Language learners with high working memory capacity have an advantage, all other factors being equal, during the second language acquisition (SLA) process; therefore, identifying a pedagogical intervention that can compensate for low working memory capacity would be advantageous to language learners and instructors. Extensive research on the…

  9. Building the Capacity of Indonesian Education Universities for ICT in Pre-Service Teacher Education: A Case Study of a Strategic Planning Exercise

    Lim, Cher Ping; Pannen, Paulina

    2012-01-01

    This paper documents how four Indonesian teacher education institutions (TEIs) engaged in strategic planning to build their capacity in developing pre-service teachers' ICT in education competencies. These TEIs adopted a holistic approach towards strategic planning by drawing upon the six dimensions of the "Capacity Building Toolkit" for…

  10. Optimization of Sex Ratio in a Selection Plan for Palas Prolificacy Line

    Răzvan Popa

    2011-05-01

    Full Text Available The aim of the paper work is to optimize the sex ratio in a selection plan, according to model developed by King (1961, which will be proposed to be applied for prolificacy improvement in Prolific Line Palas. The method used in this paper work is modeling, which exist in the most animal breeding scientifically papers. After the simulations, we observed that the most convenient variant was that which prefigure use of 13 rams on reproduction activity. This variant offer a genetic gain per generation by 0.47497 additive standard deviations.

  11. Report: EPA Needs an Agency-Wide Plan to Provide Tribal Solid Waste Management Capacity Assistance

    Report #11-P-0171, March 21, 2011. EPA cannot determine whether its efforts are assisting tribal governments in developing the capacity to manage solid waste or reduce the risks of open dumps in Indian country.

  12. Climate-proof planning for flood-prone areas : assessing the adaptive capacity of planning institutions in the Netherlands

    van den Brink, Margo; Meijerink, Sander; Termeer, Catrien; Gupta, Joyeeta

    It is generally acknowledged that adapting low-lying, flood-prone deltas to the projected impacts of climate change is of great importance. Deltas are densely populated and often subject to high risk. Climate-proof planning is, however, not only a new but also a highly complex task that poses

  13. Climate-proof planning for flood-prone areas: assessing the adaptive capacity of planning institutions in the Netherlands

    Brink, van den M.A.; Meijerink, S.; Termeer, C.J.A.M.; Gupta, J.

    2014-01-01

    It is generally acknowledged that adapting lowlying, flood-prone deltas to the projected impacts of climate change is of great importance. Deltas are densely populated and often subject to high risk. Climate-proof planning is, however, not only a new but also a highly complex task that poses

  14. Regional approach to building operational level capacity for disaster planning: the case of the Eastern Africa region.

    Bazeyo, W; Mayega, R W; Orach, G C; Kiguli, J; Mamuya, S; Tabu, J S; Sena, L; Rugigana, E; Mapatano, M; Lewy, D; Mock, N; Burnham, G; Keim, M; Killewo, J

    2013-06-01

    The Eastern Africa region is regularly affected by a variety of disasters ranging from drought, to human conflict and population displacement. The magnitude of emergencies and response capacities is similar across the region. In order to strengthen public health disaster management capacities at the operational level in six countries of the Eastern Africa region, the USAID-funded leadership project worked through the HEALTH Alliance, a network of seven schools of public health from six countries in the region to train district-level teams. To develop a sustainable regional approach to building operational level capacity for disaster planning. This project was implemented through a higher education leadership initiative. Project activities were spear-headed by a network of Deans and Directors of public health schools within local universities in the Eastern Africa region. The leadership team envisioned a district-oriented systems change strategy. Pre-service and in-service curricula were developed regionally and district teams were formed to attend short training courses. Project activities began with a situational analysis of the disaster management capacity at national and operational levels. The next steps were chronologically the formation of country training teams and training of trainers, the development of a regional disaster management training curriculum and training materials, the cascading of training activities in the region, and the incorporation of emerging issues into the training curriculum. An evaluation model included the analysis of preparedness impact of the training program. The output from the district teams was the creation of individual district-level disaster plans and their implementation. This 4-year project focused on building operational level public health emergency response capacity, which had not previously been part of any national program. Use of the all-hazard approach rather than a scenario-based contingency planning led to the

  15. Exploring the meteorological potential for planning a high performance European electricity super-grid: optimal power capacity distribution among countries

    Santos-Alamillos, Francisco J.; Brayshaw, David J.; Methven, John; Thomaidis, Nikolaos S.; Ruiz-Arias, José A.; Pozo-Vázquez, David

    2017-11-01

    The concept of a European super-grid for electricity presents clear advantages for a reliable and affordable renewable power production (photovoltaics and wind). Based on the mean-variance portfolio optimization analysis, we explore optimal scenarios for the allocation of new renewable capacity at national level in order to provide to energy decision-makers guidance about which regions should be mostly targeted to either maximize total production or reduce its day-to-day variability. The results show that the existing distribution of renewable generation capacity across Europe is far from optimal: i.e. a ‘better’ spatial distribution of resources could have been achieved with either a ~31% increase in mean power supply (for the same level of day-to-day variability) or a ~37.5% reduction in day-to-day variability (for the same level of mean productivity). Careful planning of additional increments in renewable capacity at the European level could, however, act to significantly ameliorate this deficiency. The choice of where to deploy resources depends, however, on the objective being pursued—if the goal is to maximize average output, then new capacity is best allocated in the countries with highest resources, whereas investment in additional capacity in a north/south dipole pattern across Europe would act to most reduce daily variations and thus decrease the day-to-day volatility of renewable power supply.

  16. Cell Penetrating Capacity and Internalization Mechanisms Used by the Synthetic Peptide CIGB-552 and Its Relationship with Tumor Cell Line Sensitivity.

    Astrada, Soledad; Fernández Massó, Julio Raúl; Vallespí, Maribel G; Bollati-Fogolín, Mariela

    2018-03-30

    CIGB-552 is a twenty-amino-acid novel synthetic peptide that has proven to be effective in reducing tumor size and increasing lifespan in tumor-bearing mice. Such capability is conferred by its cell-penetrating peptide character, which allows it to enter cells and elicit a pro-apoptotic effect through its major mediator, COMMD1 protein. Cell-penetrating peptides are able to use different internalization mechanisms, such as endocytosis or direct transduction through the plasma membrane. Although CIGB-552 cytotoxicity has been evaluated in several non-tumor- and tumor-derived cell lines, no data regarding the relationship between cell line sensitivity, cell penetrating capacity, the internalization mechanisms involved, COMMD1 expression levels, or its subcellular localization has yet been produced. Here, we present the results obtained from a comparative analysis of CIGB-552 sensitivity, internalization capacity and the mechanisms involved in three human tumor-derived cell lines from different origins: mammary gland, colon and lung (MCF-7, HT-29 and H460, respectively). Furthermore, cell surface markers relevant for internalization processes such as phosphatidylserine, as well as CIGB-552 target COMMD1 expression/localization, were also evaluated. We found that both endocytosis and transduction are involved in CIGB-552 internalization in the three cell lines evaluated. However, CIGB-552 incorporation efficiency and contribution of each mechanism is cell-line dependent. Finally, sensitivity was directly correlated with high internalization capacity in those cell lines where endocytosis had a major contribution on CIGB-552 internalization.

  17. Solving a Location, Allocation, and Capacity Planning Problem with Dynamic Demand and Response Time Service Level

    Carrie Ka Yuk Lin

    2014-01-01

    Full Text Available Logistic systems with uncertain demand, travel time, and on-site processing time are studied here where sequential trip travel is allowed. The relationship between three levels of decisions: facility location, demand allocation, and resource capacity (number of service units, satisfying the response time requirement, is analysed. The problem is formulated as a stochastic mixed integer program. A simulation-based hybrid heuristic is developed to solve the dynamic problem under different response time service level. An initial solution is obtained from solving static location-allocation models, followed by iterative improvement of the three levels of decisions by ejection, reinsertion procedure with memory of feasible and infeasible service regions. Results indicate that a higher response time service level could be achieved by allocating a given resource under an appropriate decentralized policy. Given a response time requirement, the general trend is that the minimum total capacity initially decreases with more facilities. During this stage, variability in travel time has more impact on capacity than variability in demand arrivals. Thereafter, the total capacity remains stable and then gradually increases. When service level requirement is high, the dynamic dispatch based on first-come-first-serve rule requires smaller capacity than the one by nearest-neighbour rule.

  18. Modelling ramp-up curves to reflect learning: improving capacity planning in secondary pharmaceutical production

    Hansen, Klaus Reinholdt Nyhuus; Grunow, Martin

    2015-01-01

    availability at market launch is ensured. Our MILP model is applied to a real industry case study using three empirically observed ramp-up curves to demonstrate its value as decision support tool. We demonstrate the superiority of our volume-dependent method over the traditional time-dependent ramp......The experience gained during production ramp-up leads to an increase of the effective production capacity over time. However, full utilisation of production capacity is not always possible during ramp-up. In such cases, the experience gained and hence the available effective capacity...... are overestimated. We develop a new method, which captures ramp-up as a function of the cumulative production volume to better reflect the experience gained while producing the new product. The use of the more accurate and computationally effective approach is demonstrated for the case of secondary pharmaceutical...

  19. Capacity factor prediction and planning in the wind power generation industry

    Gurgur, Cigdem Z. [Department of Management and Marketing, Richard T. Doermer School of Business and Management Sciences, Indiana - Purdue University, 2101 Coliseum Blvd. East, Fort Wayne, IN 46805 (United States); Jones, Michael [Xcel Energy, Denver, CO 80223 (United States)

    2010-12-15

    The common practice to calculate wind generation capacity values relies more on heuristic approximations than true system estimations. In this paper we proposed a more accurate method. In the first part of our analysis, a Monte Carlo simulation was created based on Markov chains to provide an independent estimate of the true behavior of wind farm capacity value as a function of system penetration. With this curve as a baseline, a technique for using beta distributions to model the input variables was adopted. A final step to increase accuracy involved the use of numerical convolution within the program to eliminate summation estimates. (author)

  20. Serotonin-mediated central fatigue underlies increased endurance capacity in mice from lines selectively bred for high voluntary wheel running.

    Claghorn, Gerald C; Fonseca, Ivana A T; Thompson, Zoe; Barber, Curtis; Garland, Theodore

    2016-07-01

    Serotonin (5-hydroxytryptamine; 5-HT) is implicated in central fatigue, and 5-HT1A pharmaceuticals are known to influence locomotor endurance in both rodents and humans. We studied the effects of a 5-HT1A agonist and antagonist on both forced and voluntary exercise in the same set of mice. This cohort of mice was taken from 4 replicate lines of mice that have been selectively bred for high levels of voluntary wheel running (HR) as compared with 4 non-selected control (C) lines. HR mice run voluntarily on wheels about 3× as many revolutions per day as compared with C, and have greater endurance during forced treadmill exercise. We hypothesized that drugs targeting serotonin receptors would have differential effects on locomotor behavior of HR and C mice. Subcutaneous injections of a 5-HT1A antagonist (WAY-100,635), a combination of 5-HT1A agonist and a 5-HT1A/1B partial agonist (8-OH-DPAT+pindolol), or physiological saline were given to separate groups of male mice before the start of each of three treadmill trials. The same manipulations were used later during voluntary wheel running on three separate nights. WAY-100,635 decreased treadmill endurance in HR but not C mice (dose by linetype interaction, P=0.0014). 8-OH-DPAT+pindolol affected treadmill endurance (PWheel running was reduced in HR but not C mice at the highest dose of 8-OH-DPAT+pindolol (dose by linetype, P=0.0221), but was not affected by WAY-100,635 treatment. These results provide further evidence that serotonin signaling is an important determinant of performance during both forced and voluntary exercise. Although the elevated wheel running of HR mice does not appear related to alterations in serotonin signaling, their enhanced endurance capacity does. More generally, our results indicate that both forced and voluntary exercise can be affected by an intervention that acts (primarily) centrally. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Guided preparedness planning with lay communities: enhancing capacity of rural emergency response through a systems-based partnership.

    McCabe, O Lee; Perry, Charlene; Azur, Melissa; Taylor, Henry G; Gwon, Howard; Mosley, Adrian; Semon, Natalie; Links, Jonathan M

    2013-02-01

    , LHDs, FBOs, and AHCs can work effectively to plan, implement, and evaluate what appears to be an effective, practical, and durable model of capacity building for public mental health emergency planning.

  2. The Art of Capacity Planning Being Ready for the Big Growth Spurt

    Allspaw, John

    2009-01-01

    Web-based companies live or die by the ability to scale their infrastructure to accommodate increasing demand. This book is a hands-on and practical guide to planning for such growth, with many techniques and considerations to help you plan, deploy, and manage web application infrastructure. Written by the manager of data operations for the world-famous photo-sharing site Flickr.com, the author offers advice based on years of valuable experience.

  3. LINES

    Minas Bakalchev

    2015-10-01

    Full Text Available The perception of elements in a system often creates their interdependence, interconditionality, and suppression. The lines from a basic geometrical element have become the model of a reductive world based on isolation according to certain criteria such as function, structure, and social organization. Their traces are experienced in the contemporary world as fragments or ruins of a system of domination of an assumed hierarchical unity. How can one release oneself from such dependence or determinism? How can the lines become less “systematic” and forms more autonomous, and less reductive? How is a form released from modernistic determinism on the new controversial ground? How can these elements or forms of representation become forms of action in the present complex world? In this paper, the meaning of lines through the ideas of Le Corbusier, Leonidov, Picasso, and Hitchcock is presented. Spatial research was made through a series of examples arising from the projects of the architectural studio “Residential Transformations”, which was a backbone for mapping the possibilities ranging from playfulness to exactness, as tactics of transformation in the different contexts of the contemporary world.

  4. Orthopaedic Trauma Care Capacity Assessment and Strategic Planning in Ghana: Mapping a Way Forward.

    Stewart, Barclay T; Gyedu, Adam; Tansley, Gavin; Yeboah, Dominic; Amponsah-Manu, Forster; Mock, Charles; Labi-Addo, Wilfred; Quansah, Robert

    2016-12-07

    Orthopaedic conditions incur more than 52 million disability-adjusted life years annually worldwide. This burden disproportionately affects low and middle-income countries, which are least equipped to provide orthopaedic care. We aimed to assess orthopaedic capacity in Ghana, describe spatial access to orthopaedic care, and identify hospitals that would most improve access to care if their capacity was improved. Seventeen perioperative and orthopaedic trauma care-related items were selected from the World Health Organization's Guidelines for Essential Trauma Care. Direct inspection and structured interviews with hospital staff were used to assess resource availability and factors contributing to deficiencies at 40 purposively sampled facilities. Cost-distance analyses described population-level spatial access to orthopaedic trauma care. Facilities for targeted capability improvement were identified through location-allocation modeling. Orthopaedic trauma care assessment demonstrated marked deficiencies. Some deficient resources were low cost (e.g., spinal immobilization, closed reduction capabilities, and prosthetics for amputees). Resource nonavailability resulted from several contributing factors (e.g., absence of equipment, technology breakage, lack of training). Implants were commonly prohibitively expensive. Building basic orthopaedic care capacity at 15 hospitals without such capacity would improve spatial access to basic care from 74.9% to 83.0% of the population (uncertainty interval [UI] of 81.2% to 83.6%), providing access for an additional 2,169,714 Ghanaians. The availability of several low-cost resources could be better supplied by improvements in organization and training for orthopaedic trauma care. There is a critical need to advocate and provide funding for orthopaedic resources. These initiatives might be particularly effective if aimed at hospitals that could provide care to a large proportion of the population.

  5. Urethrography and ischial intertuberosity line in radiation therapy planning for prostate carcinoma

    Sadeghi, Ahmad; Kuisk, Hans; Tran, Luu; St Royal, Leslie

    1996-01-01

    We analyzed our urethrography procedure regarding the validity of using the ischial tuberosity line (ITL) as the caudal margin of treatment portals for prostate carcinoma. The distances of the external urethral sphincter and the lowest margin of the opacified urinary bladder were analyzed in one hundred fifteen consecutive urethrograms. None showed the urethral sphincter to be caudal to the ITL. Ten percent of the sphincters were located less than 1.0 cm cephalad to the ITL, yielding inadequate treatment coverage if the ITL was relied on. Arbitrarily considering 2.0 cm or more of the urethral irradiation to be excessive, the use of the ITL would then have resulted in unnecessary normal tissue irradiation of 42.5%. The ITL should not be used as the caudal margin for prostate treatment portals. Variation in sphincter position, as also seen on lateral projections, reveal a need for urethrography as a necessary supplement to computed tomography to plan radiation portals for prostate cancer

  6. Environmental and economic appraisal of power generation capacity expansion plan in Nigeria

    Gujba, H.; Mulugetta, Y.; Azapagic, A.

    2010-01-01

    The power sector in Nigeria is undergoing structural reforms aimed at improving and expanding the current grid generation capacity and distribution network. The Government has injected huge funds into this sector while also granting licences to private companies for the provision of electricity. It is also aiming to increase electricity generation capacity to 25,000 MW by 2020 from the current installed capacity of 6500 MW while also pledging to connect 75% of the population to the grid from the current 40% by 2025. This paper sets out to analyse the implications of the energy policy in Nigeria and presents the life cycle environmental and economic analysis of the current and future electricity sector. The results show that all the life cycle impacts and economic costs increase significantly over the time-period (2003-2030), but at different rates depending on the types of technologies deployed. Renewables such as large hydro and solar proposed by the Government have a potential to reduce the overall life cycle environmental impacts from the electricity mix, considering their lower environmental impacts compared to fossil-fuels. However, this requires a five-fold increase in grid investments from the current US$1.7 billion per year to US$9.40 billion by 2030.

  7. Adverse effects of reduced oxygen tension on the proliferative capacity of rat kidney and insulin-secreting cell lines involve DNA damage and stress responses

    Chen Jianhua; Jones, R. Huw; Tarry-Adkins, Jane; Smith, Noel H.; Ozanne, Susan E.

    2008-01-01

    Standard cell culture conditions do not reflect the physiological environment in terms of oxygen tension (20% vs 3%). The effects of lowering oxygen tension on cell proliferation in culture can be beneficial as well as detrimental depending on the cell line studied, but the molecular mechanism underlying such effects is not fully understood. We observed that the proliferative capacity of the rat cell lines NRK and INS-1 was inhibited when cultured under 3% oxygen as compared to 20% oxygen. Suppression of proliferation in NRK cells was accompanied by induction of DNA double strand breaks whereas in INS-1 cells it was accompanied by up-regulation of p53 and p27. Although Sirt1 was up-regulated in both cell lines by 3% oxygen the effects on antioxidant enzymes (MnSOD, CuZnSOD and catalase) were cell line specific. Marked up-regulation of heme oxygenase-1 (HO-1) was detected in both NRK and INS-1 cells when cultured in 3% oxygen. HO-1 expression can be readily induced by exposure to hydrogen peroxide in culture. These results suggest that reduced oxygen tension suppresses the proliferative capacity of these two cell lines through a stress response that is similar to an oxidative stress response but the molecular events that lead to the reduced cell proliferation are cell line specific

  8. The Effects of Pre-Task, On-Line, and Both Pre-Task and On-Line Planning on Fluency, Complexity, and Accuracy--The Case of Iranian EFL Learners' Written Production

    Piri, Faramarz; Barati, Hossein; Ketabi, Saeed

    2012-01-01

    Previous studies on the effect of planning on language production have revealed that planning does have a positive effect on language performance in terms of fluency, complexity, and accuracy. The present study was an attempt to investigate the effects of pre-task, on-line, and both pre-task and on-line planning on fluency, accuracy, and…

  9. Critical care medicine as a distinct product line with substantial financial profitability: the role of business planning.

    Bekes, Carolyn E; Dellinger, R Phillip; Brooks, Daniel; Edmondson, Robert; Olivia, Christopher T; Parrillo, Joseph E

    2004-05-01

    As academic health centers face increasing financial pressures, they have adopted a more businesslike approach to planning, particularly for discrete "product" or clinical service lines. Since critical care typically has been viewed as a service provided by a hospital, and not a product line, business plans have not historically been developed to expand and promote critical care. The major focus when examining the finances of critical care has been cost reduction, not business development. We hypothesized that a critical care business plan can be developed and analyzed like other more typical product lines and that such a critical care product line can be profitable for an institution. In-depth analysis of critical care including business planning for critical care services. Regional academic health center in southern New Jersey. None. As part of an overall business planning process directed by the Board of Trustees, the critical care product line was identified by isolating revenue, expenses, and profitability associated with critical care patients. We were able to identify the major sources ("value chain") of critical care patients: the emergency room, patients who are admitted for other problems but spend time in a critical care unit, and patients transferred to our intensive care units from other hospitals. The greatest opportunity to expand the product line comes from increasing the referrals from other hospitals. A methodology was developed to identify the revenue and expenses associated with critical care, based on the analysis of past experience. With this model, we were able to demonstrate a positive contribution margin of dollar 7 million per year related to patients transferred to the institution primarily for critical care services. This can be seen as the profit related to the product line segment of critical care. There was an additional positive contribution margin of dollar 5.8 million attributed to the critical care portion of the hospital stay of

  10. Assessing and controlling the impact of hospital capacity planning on the waiting time

    Dellaert, N.; Çayiroglu, E.; Jeunet, J.

    2015-01-01

    In the literature, tactical plans of elective patients aim at increasing hospital efficiency through a better resource utilisation, although hospitals claim that patient satisfaction, usually measured by the waiting time, is also important. In this regard, the purpose of this paper is to show how

  11. Community Wildfire Protection Planning: The Importance of Framing, Scale, and Building Sustainable Capacity

    Daniel R. Williams; Pamela J. Jakes; Sam Burns; Antony S. Cheng; Kristen C. Nelson; Victoria Sturtevant; Rachel F. Brummel; Emily Staychock; Stephanie G. Souter

    2012-01-01

    Community wildfire protection planning has become an important tool for engaging wildland-urban interface residents and other stakeholders in efforts to address their mutual concerns about wildland fire management, prioritize hazardous fuel reduction projects, and improve forest health. Drawing from 13 case studies from across the United States, this article describes...

  12. Facility location, capacity acquisition and technology selection models for manufacturing strategy planning

    Verter, Vedat

    1993-01-01

    Ankara : The Institute of Engineering and Science, Bilkent Univ., 1993. Thesis (Ph.D.) -- Bilkent University, 1993. Includes bibliographical references leaves 129-141. The primary aim of this dissertation research is to contribute to the manufacturing strategy planning process. The firm is perceived as a value chain which can be represented by a production-distribution network. Structural decisions regarding the value chain of a firm are the means to implement the firm’s manufacturin...

  13. Evaluation of the radioinduced damage, repair capacity and cell death on human tumorigenic (T-47D and MCF-7) and nontumorigenic (MCF-10) cell lines of breast

    Valdoge, Flavia Gomes Silva

    2008-01-01

    Breast cancer is one of the most common malignancies that account women, representing about one in three of all female neoplasm. Approximately, 90% of cases are considered sporadic, attributed to somatic events and about 10% have a family history and this only 4 - 5 % is due to hereditary factors. In the clinic, ionizing radiation is a major tool utilized in the control of tumour growth, besides surgery and chemotherapy. There is, however, little information concerning cellular response to the action of ionizing radiation in the target cells, i.e., cell lines originating from breast cancer. The present study proposed to analyze the radiosensitivity of the human tumorigenic (T-47D and MCF-7) and non tumorigenic (MCF-10) cell lines, originating from breast and submitted to various doses (0.5 to 30 Gy) of 60 Co rays (0.72 - 1.50 Gy/min). For this purpose, DNA radioinduced damage, repair capacity and cell death were utilized as parameters of radiosensitivity by micronucleus, single cell gel electrophoresis (Comet assay) and cell viability techniques. The data obtained showed that tumorigenic cell lines were more radiosensitive than non tumorigenic breast cells in all assays here utilized. The T-47D cell line was presenting the highest amount of radioinduced damage, a more accelerated proliferation rate and a higher rate of cell death. The three cell lines presented a relatively efficient repair capacity, since one hour after the irradiation all of them showed a considerable reduction of radioinduced damage. The techniques employed showed to be secure, sensitive and reproducible, allowing to quantify and evaluate DNA damage, repair capacity and cell death in the three human breast cell lines. (author)

  14. Carrying Capacity

    Schroll, Henning; Andersen, Jan; Kjærgård, Bente

    2012-01-01

    A spatial planning act was introduced inIndonesia 1992 and renewed in 2008. It emphasised the planning role of decentralised authorities. The spatial planning act covers both spatial and environmental issues. It defines the concept of carrying capacity and includes definitions of supportive....../cities. Four different sectors (water, food production, waste, and forests) were selected as core areas for decentralised spatial planning. Indicators for SCC and ACC were identified and assessed with regard to relevance and quantifiability. For each of the indicators selected, a legal threshold or guiding...... was introduced inIndonesia 1992 and renewed in 2008. It emphasised the planning role of decentralised authorities. The spatial planning act covers both spatial and environmental issues. It defines the concept of carrying capacity and includes definitions of supportive carrying capacity (SCC) and assimilative...

  15. HVDC-System-Interaction Assessment through Line-Flow Change-Distribution Factor and Transient-Stability Analysis at Planning Stage

    Sungchul Hwang

    2016-12-01

    Full Text Available Many of the recent projects for new transmission line have considered the high-voltage direct current (HVDC system, owing to the many advantages of the direct current (DC system. The most noteworthy advantage is that a cable can serve as a substitute for the overhead transmission line in residential areas; therefore, the HVDC system application is increasing, and as the number of DC systems in the power system increases, the interaction assessment regarding the HVDC system gains importance. An index named multi-infeed interaction factor (MIIF is commonly used to estimate the interaction between power converters; however, the HVDC system is composed of two converters and a transmission line. The MIIF represents the interaction between the rectifiers and inverters, but not for the whole system. In this work, a method to assess the interaction of the whole system was therefore studied. To decide on the location of the new HVDC transmission system at the planning stage, in consideration of the interaction of the existing DC system, the line flow change distribution factor, according to the HVDC-transmission capacity change, was examined. Also, a power system transient -stability analysis was performed with different HVDC system locations, depending on the distribution factor. The simulation results indicate that when the factor is higher, two HVDC systems have a stronger interaction and are less stable in the transient state.

  16. Deployment Strategy for Charging Piles Based on Distribution Network Capacity Planning and Users’ Needs

    Du Chongyang

    2015-01-01

    Full Text Available Electric vehicles are the most potential transports in the future. However, the large scale of charging facilities will make a great influence on gird. There is a need to make a research on the construction of charging facilities. Based on the power demand characteristics of electric vehicle charging, distribution network capacity, charging system performance and other aspects, this paper mainly researched the deployment strategy of charging piles. First, the authors built up a model with characteristics of charging power demand of electric vehicle and a model of charging service system. The characteristic of daily load curve is analyzed. Second, based on these works, the authors designed the progress of strategy making. At last, the progress was verified by the actual use case.

  17. Recovery Plans and the Balancing of Fishing Capacity and Fishing Possibilities

    Hegland, Troels Jacob; Raakjær, Jesper

    2008-01-01

    ABSTRACT: The Common Fisheries Policy (CFP) of the European Union (EU) has for long been accused of being unable to provide sustainable fisheries or actually in itself being an obstacle to this. Not least the inability of the CFP to achieve a sustainable balance between available resources and fi...... present resource crisis has opened a window-of-opportunity which makes a change in course possible. This is to some extent evidenced by the adoption of a series of recovery plans. Whether this will be enough to provide for a bright future of the CFP is, however, questionable....

  18. Plans for an on-line computer at the Finnish TRIGA Laboratory

    Junttila, J.; Tamminen, A.; Palmgren, A.

    1970-01-01

    Full text: The future plans at the Helsinki Triga reactor include an on-line computer system. The project is in its pre-planning stage, and if the financing can be arranged, the instancing is preliminarily scheduled to start in 1972. We estimate the probability of getting a computer to be 90%. The tasks of the system would be the monitoring and control of reactor power level and other operating conditions, and, on the other hand, data acquisition, analysis and apparatus control in different reactor laboratory experiments. These include the neutron diffractometer, the cold neutron facility and neutron TOF-measurements, gamma-spectroscopy, reactor noise measurements, and neutron activation analysis. It is our intention to purchase a medium-sized computer which is presently being developed by the Finnish company Oy Stroemberg Ab. This computer has been constructed by using the time sharing principle. Consequently, background jobs like testing of new programs, off-line calculations etc., can be executed simultaneously with the actual data taking and control operations. The interfering of programs with each other is prevented by dividing the programs in protected segments. Different kinds of devices and functions can be added to the basic control processing unit, e.g. an automatic interrupt unit with up to 128 priority levels, a fast floating point arithmetic unit, and the control of a direct memory access channel. An additional fact, which makes this particular computer attractive to us, is that we wish to have the manufacturer's support in designing our special applications. The initial system cost of about 120.000 US$ is considered justified for three reasons of about equal importance: 1. The operation and utilization of our reactor will become more efficient. 2. All people involved in the project will learn how to handle a rather complicated-computerization project. 3. The Finnish Government can support the development of this computer by ordering one or two

  19. A New Methodology for Solving Trajectory Planning and Dynamic Load-Carrying Capacity of a Robot Manipulator

    Wanjin Guo

    2016-01-01

    Full Text Available A new methodology using a direct method for obtaining the best found trajectory planning and maximum dynamic load-carrying capacity (DLCC is presented for a 5-degree of freedom (DOF hybrid robot manipulator. A nonlinear constrained multiobjective optimization problem is formulated with four objective functions, namely, travel time, total energy involved in the motion, joint jerks, and joint acceleration. The vector of decision variables is defined by the sequence of the time-interval lengths associated with each two consecutive via-points on the desired trajectory of the 5-DOF robot generalized coordinates. Then this vector of decision variables is computed in order to minimize the cost function (which is the weighted sum of these four objective functions subject to constraints on joint positions, velocities, acceleration, jerks, forces/torques, and payload mass. Two separate approaches are proposed to deal with the trajectory planning problem and the maximum DLCC calculation for the 5-DOF robot manipulator using an evolutionary optimization technique. The adopted evolutionary algorithm is the elitist nondominated sorting genetic algorithm (NSGA-II. A numerical application is performed for obtaining best found solutions of trajectory planning and maximum DLCC calculation for the 5-DOF hybrid robot manipulator.

  20. Development of urban planning guidelines for improving emergency response capacities in seismic areas of Iran.

    Hosseini, Kambod Amini; Jafari, Mohammad Kazem; Hosseini, Maziar; Mansouri, Babak; Hosseinioon, Solmaz

    2009-10-01

    This paper presents the results of research carried out to improve emergency response activities in earthquake-prone areas of Iran. The research concentrated on emergency response operations, emergency medical care, emergency transportation, and evacuation-the most important issues after an earthquake with regard to saving the lives of victims. For each topic, some guidelines and criteria are presented for enhancing emergency response activities, based on evaluations of experience of strong earthquakes that have occurred over the past two decades in Iran, notably Manjil (1990), Bam (2003), Firouz Abad-Kojour (2004), Zarand (2005) and Broujerd (2006). These guidelines and criteria are applicable to other national contexts, especially countries with similar seismic and social conditions as Iran. The results of this study should be incorporated into comprehensive plans to ensure sustainable development or reconstruction of cities as well as to augment the efficiency of emergency response after an earthquake.

  1. A test plan for an on-line whole building energy calculator

    Purdy, J.; Ferguson, A.; Mombourquette, S.; Haddad, K.; Lopez, P.; Wyndham-Wheeler, P.; Henry, S. [CANMET Energy Technology Centre, Natural Resources, Ottawa, Ont. (Canada)

    2008-04-15

    This paper presents the testing of a dynamic on-line whole-building energy calculator. The tool consists of a web-based interface for user inputs; an application to create the simulation input files from these user inputs; a simulation engine; and an application for passing the simulation engine output back to the interface and user. A detailed test protocol, composed of three parts, was developed as part of the software development process for quality assurance purposes. This paper will present the tasks specific to the development of the simulation engine, including, the definition of the required user inputs, the creation of default house archetypes, and the definition of the results to be presented to the user. It will also investigate the three parts of the test plan as well as the task automation tools developed to facilitate the testing. The use of these tools proved very useful given the large number of combinations of user inputs at the web interface and input files to the simulation engine. The findings show the importance of having a detailed and comprehensive test protocol during the software development phase. (author)

  2. Evaluating the strategic capacity of collaborative spatial planning initiatives by the performance of its process, output and outcomes: The case of the southern Randstad Holland

    Harteveld, E.; Waterhout, B.; Broekhans, B.; Zonneveld, W.A.M.

    2015-01-01

    Spatial planning practices are constantly evolving to be more effective in a dynamic context. In the face of the latest developments, the practice of collaborative spatial planning through the formation of regional collaborations has emerged as the contemporary solution. The practice of working with a multitude of public actors that cooperate to formulate spatial strategies for issues that transcend their own planning capacity is relatively new and the ideal structure, organization and scope ...

  3. Strategic design and investment capacity planning of the ethanol supply chain under price uncertainty

    Dal-Mas, Matteo; Giarola, Sara; Zamboni, Andrea; Bezzo, Fabrizio

    2011-01-01

    Fossil fuel depletion and the increase of greenhouse gases emissions has been pushing the search for alternative fuels for automotive transport. The European Union has identified biofuel technology as one option for reducing its dependence on imported energy. Ethanol is a promising biofuel, but great uncertainty on the business profitability has recently determined a slowdown in the industry expansion. In particular, geographical plant location, biomass price fluctuation and fuel demand variability severely constrain the economic viability of new ethanol facilities. In this work a dynamic, spatially explicit and multi-echelon Mixed Integer Linear Program (MILP) modeling framework is presented to help decision-makers and potential investors assessing economic performances and risk on investment of the entire biomass-based ethanol supply chain. A case study concerning the corn-to-ethanol production supply chain in Northern Italy is used to demonstrate the effectiveness of the proposed modeling approach. The mathematical pattern addresses the issue of optimizing the ethanol supply network over a ten years' time period under uncertainty on biomass production cost and product selling price. The model allows optimizing economic performances and minimize financial risk on investment by identifying the best network topology in terms of biomass cultivation site locations, ethanol production plant capacities, location and transport logistics. -- Highlights: →A dynamic spatially explicit Mixed Integer Linear Program (MILP) of the entire corn-based ethanol supply chain is proposed. →Uncertainty on corn price and ethanol selling price is taken into account. →The model allows assessing and optimizing the supply chain economic performance and risk on investment. →A case study concerning the corn-to-ethanol production in Northern Italy demonstrates the effectiveness of the approach.

  4. Partnership capacity for community health improvement plan implementation: findings from a social network analysis.

    McCullough, J Mac; Eisen-Cohen, Eileen; Salas, S Bianca

    2016-07-13

    Many health departments collaborate with community organizations on community health improvement processes. While a number of resources exist to plan and implement a community health improvement plan (CHIP), little empirical evidence exists on how to leverage and expand partnerships when implementing a CHIP. The purpose of this study was to identify characteristics of the network involved in implementing the CHIP in one large community. The aims of this analysis are to: 1) identify essential network partners (and thereby highlight potential network gaps), 2) gauge current levels of partner involvement, 3) understand and effectively leverage network resources, and 4) enable a data-driven approach for future collaborative network improvements. We collected primary data via survey from n = 41 organizations involved in the Health Improvement Partnership of Maricopa County (HIPMC), in Arizona. Using the previously validated Program to Analyze, Record, and Track Networks to Enhance Relationships (PARTNER) tool, organizations provided information on existing ties with other coalition members, including frequency and depth of partnership and eight categories of perceived value/trust of each current partner organization. The coalition's overall network had a density score of 30 %, degree centralization score of 73 %, and trust score of 81 %. Network maps are presented to identify existing relationships between HIPMC members according to partnership frequency and intensity, duration of involvement in the coalition, and self-reported contributions to the coalition. Overall, number of ties and other partnership measures were positively correlated with an organization's perceived value and trustworthiness as rated by other coalition members. Our study presents a novel use of social network analysis methods to evaluate the coalition of organizations involved in implementing a CHIP in an urban community. The large coalition had relatively low network density but high

  5. Increasing Student Interest and Comprehension of Production Planning and Control and Operations Performance Measurement Concepts Using a Production Line Game

    Cox, James F., III; Walker, Edward D., II

    2005-01-01

    Production planning and control (PPC) systems and operations performance measures are topics that students generally find both boring and difficult to understand. In the article, the authors present a production line game that they have found to be an effective tool to increase student interest in the topics as well as student comprehension. The…

  6. Bird on the wire: Landscape planning considering costs and benefits for bird populations coexisting with power lines.

    D'Amico, Marcello; Catry, Inês; Martins, Ricardo C; Ascensão, Fernando; Barrientos, Rafael; Moreira, Francisco

    2018-02-24

    Power-line grids are increasingly expanding worldwide, as well as their negative impacts on avifauna, namely the direct mortality through collision and electrocution, the reduction of breeding performance, and the barrier effect. On the other hand, some bird species can apparently benefit from the presence of power lines, for example perching for hunting purposes or nesting on electricity towers. In this perspective essay, we reviewed the scientific literature on both costs and benefits for avifauna coexisting with power lines. Overall, we detected a generalized lack of studies focusing on these costs or benefits at a population level. We suggest that a switch in research approach to a larger spatio-temporal scale would greatly improve our knowledge about the actual effects of power lines on bird populations. This research approach would facilitate suitable landscape planning encompassing both mitigation of costs and promotion of benefits for bird populations coexisting with power lines. For example, the strategic route planning of electricity infrastructures would limit collision risk or barrier effects for threatened bird populations. Concurrently, this strategic route planning would promote the range expansion of threatened populations of other bird species, by providing nesting structures in treeless but potentially suitable landscapes. We suggest establishing a collaborative dialogue among the scientific community, governments, and electricity companies, with the aim to produce a win-win scenario in which both biodiversity conservation and infrastructure development are integrated in a common strategy.

  7. Insertion device and beam line plans for the Advanced Photon Source: A report and recommendations by the Insertion Device and Beam Line Planning Committee

    1988-02-01

    In the 7-GeV Advanced Photon Source (APS) Conceptual Design Report (CDR), fifteen complete experimental beam lines were specified in order to establish a representative technical and cost base for the components involved. In order to optimize the composition of the insertion devices and the beam line, these funds are considered a ''Trust Fund.'' The present report evaluates the optimization for the distribution of these funds so that the short- and long-term research programs will be most productive, making the facility more attractive from the user's point of view. It is recommended that part of the ''Trust Fund'' be used for the construction of the insertion devices, the front-end components, and the first-optics, minimizing the cost to potential users of completing a beam line. In addition, the possibility of cost savings resulting from replication and standardization of high multiplicity components (such as IDs, front ends, and first-optics instrumentation) is addressed. 2 refs., 5 tabs

  8. The Palau AHEC--academizing the public health work plan: capacity development and innovation in Micronesia.

    Dever, Greg; Finau, Sitaleki; Kuartei, Stevenson; Durand, A Mark; Rykken, David; Yano, Victor; Untalan, Pedro; Withy, Kelley; Tellei, Patrick; Baravilala, Wame; Pierantozzi, Sandra; Tellei, Jullie

    2005-03-01

    The Palau Area Health Education Center (AHEC)--a program of the University of Hawaii's John A. Burns School of Medicine (JABSOM) and based at Palau Community College--was established in 2001 in response to the recommendations of the 1998 Institute of Medicine (IOM) report--Pacific Partnerships for Health--Charting a New Course for the 21st Century1. One of IOM's core recommendations was to promote the training of the primary health care workforce among the U.S.-Associated Pacific Islands. Since its inception in 2001, the Palau AHEC has coordinated overall 37 postgraduate and undergraduate courses in General Practice and Public Health taught by the University of Auckland Faculty of Medicine and Health Sciences and the Fiji School of Medicine's School of Public Health and Primary Care (SPH&PC) in Palau, Yap State, and the Republic of the Marshall Islands. Currently 139 physicians, nurses, health administrators, and environmental health workers are registered as active students in Palau (58), Yap State (22), and the RMI (59). Notably, the Palau AHEC and the SPH&PC have worked in an innovative partnership with the Palau Ministry of Health to operationalize the MOH's public health work plan to implement a comprehensive community health survey of all 4,376 households in Palau, interviewing 79% of the total population, to determine Palau's health indicators. To accomplish this, the SPH&PC developed and taught a curriculum for Palau physicians and public health nurses on how to design the survey, gather, and analyze data in order to develop and implement appropriately responsive intervention and treatment programs to address Palau's old and newer morbidities. In early FY2005, two other Micronesian AHECs--the Yap State and Commonwealth of the Northern Mariana Islands AHECs--were funded through JABSOM administered grants which will also address the primary care training needs of Micronesia's remote and isolated health workforce.

  9. Integration of on-line imaging, plan adaptation and radiation delivery: proof of concept using digital tomosynthesis

    Mestrovic, Ante; Otto, Karl; Nichol, Alan; Clark, Brenda G

    2009-01-01

    The main objective of this manuscript is to propose a new approach to on-line adaptive radiation therapy (ART) in which daily image acquisition, plan adaptation and radiation delivery are integrated together and performed concurrently. A method is described in which on-line ART is performed based on intra-fractional digital tomosynthesis (DTS) images. Intra-fractional DTS images were reconstructed as the gantry rotated between treatment positions. An edge detection algorithm was used to automatically segment the DTS images as the gantry arrived at each treatment position. At each treatment position, radiation was delivered based on the treatment plan re-optimized for the most recent DTS image contours. To investigate the feasibility of this method, a model representing a typical prostate, bladder and rectum was used. To simulate prostate deformations, three clinically relevant, non-rigid deformations (small, medium and large) were modeled by systematically deforming the original anatomy. Using our approach to on-line ART, the original treatment plan was successfully adapted to arrive at a clinically acceptable plan for all three non-rigid deformations. In conclusion, we have proposed a new approach to on-line ART in which plan adaptation is performed based on intra-fractional DTS images. The study findings indicate that this approach can be used to re-optimize the original treatment plan to account for non-rigid anatomical deformations. The advantages of this approach are 1) image acquisition and radiation delivery are integrated in a single gantry rotation around the patient, reducing the treatment time, and 2) intra-fractional DTS images can be used to detect and correct for patient motion prior to the delivery of each beam (intra-fractional patient motion).

  10. An Observational Assessment of Anesthesia Capacity in Madagascar as a Prerequisite to the Development of a National Surgical Plan.

    Baxter, Linden S; Ravelojaona, Vaonandianina A; Rakotoarison, Hasiniaina N; Herbert, Alison; Bruno, Emily; Close, Kristin L; Andean, Vanessa; Andriamanjato, Hery H; Shrime, Mark G; White, Michelle C

    2017-06-01

    The global lack of anesthesia capacity is well described, but country-specific data are needed to provide country-specific solutions. We aimed to assess anesthesia capacity in Madagascar as part of the development of a Ministry of Health national surgical plan. As part of a nationwide surgical safety quality improvement project, we surveyed 19 of 22 regional hospitals, representing surgical facilities caring for 75% of the total population. The assessment was divided into 3 areas: anesthesia workforce density, infrastructure and equipment, and medications. Data were obtained by semistructured interviews with Ministry of Health officials, hospital directors, technical directors, statisticians, pharmacists, and anesthesia providers and through on-site observations. Interview questions were adapted from the World Health Organization Situational Analysis Tool and the World Federation of Societies of Anaesthesiologists International Standards for Safe Practice of Anaesthesia. Additional data on workforce density were collected from the 3 remaining regions so that workforce density data are representative of all 22 regions. Anesthesia physician workforce density is 0.26 per 100,000 population and 0.19 per 100,000 outside of the capital region. Less than 50% of hospitals surveyed reported having a reliable electricity and oxygen supply. The majority of anesthesia providers work without pulse oximetry (52%) or a functioning vaporizer (52%). All the hospitals surveyed had very basic pediatric supplies, and none had a pediatric pulse oximetry probe. Ketamine is universally available but more than 50% of hospitals lack access to opioids. None of the 19 regional hospitals surveyed was able to completely meet the World Federation of Societies of Anaesthesiologists' standards for monitoring. Improving anesthesia care is complex. Capacity assessment is a first step that would enable progress to be tracked against specific targets. In Madagascar, scale-up of the anesthesia

  11. Cross case analysis of institutions and adaptive capacity in The Netherlands: Do institutions for spatial planning, water and nature management in The Netherlands enhance the capacity of society to adapt to climate change?

    Meijerink, S.; Bergsma, E.; Gupta, J.; Jong, P.; Klostermann, J.E.M.; Termeer, C.J.A.M.

    2010-01-01

    In this working document we aim to answer the following question: Do institutions for spatial planning, water and nature management in the Netherlands enhance the capacity of society to adapt to climate change? To answer this question we have first reviewed the literature on adaptive governance and

  12. Amla Enhances Mitochondrial Spare Respiratory Capacity by Increasing Mitochondrial Biogenesis and Antioxidant Systems in a Murine Skeletal Muscle Cell Line

    Hirotaka Yamamoto

    2016-01-01

    Full Text Available Amla is one of the most important plants in Indian traditional medicine and has been shown to improve various age-related disorders while decreasing oxidative stress. Mitochondrial dysfunction is a proposed cause of aging through elevated oxidative stress. In this study, we investigated the effects of Amla on mitochondrial function in C2C12 myotubes, a murine skeletal muscle cell model with abundant mitochondria. Based on cell flux analysis, treatment with an extract of Amla fruit enhanced mitochondrial spare respiratory capacity, which enables cells to overcome various stresses. To further explore the mechanisms underlying these effects on mitochondrial function, we analyzed mitochondrial biogenesis and antioxidant systems, both proposed regulators of mitochondrial spare respiratory capacity. We found that Amla treatment stimulated both systems accompanied by AMPK and Nrf2 activation. Furthermore, we found that Amla treatment exhibited cytoprotective effects and lowered reactive oxygen species (ROS levels in cells subjected to t-BHP-induced oxidative stress. These effects were accompanied by increased oxygen consumption, suggesting that Amla protected cells against oxidative stress by using enhanced spare respiratory capacity to produce more energy. Thus we identified protective effects of Amla, involving activation of mitochondrial function, which potentially explain its various effects on age-related disorders.

  13. Pneumococcal Replicative State in Relation to its Adherence Capacity to A549-cell Line: A Preliminary in vitro Analysis

    Mohd Desa, M. N.

    2011-01-01

    Full Text Available This study was to compare the replication capacity of pneumococcal isolates (serotypes 1, 7F, 19F and 23F with their adherence pattern to monolayer cells (A549. For standardization purposes, all isolates showed a normal growth curve in both bacteriological (THB + 0.5% yeast extract with and without 2% FBS and cell culture media (RPMI + 2% FBS. In the former media, a shorter lag phase was observed for isolate serotypes 1 and 7F in presence of serum while in the later; growth yield was lower for all isolates with stationary phase approaching OD600 of 0.01 as compared to 1.0 in bacteriological media. In the replicative analysis at different growth phases of the isolates in cell culture media, growth capacity at 3 h post-incubation was frequently twice as that at 1 h, and that at early-log phase was frequently higher than that at mid-log phase at both post-incubation times. Adherence was frequently the least at early-log phase although the isolates were in the most active state of replication to increase the number of pneumococcal cells to adhere. At mid- and late-log phases, pneumococcal adherence was frequently higher although the replication was reduced. This study marks the potential correlation between pneumococcal growth fitness and adherence capacity whereby the later may not be superior during the early growth phase.

  14. Evaluation of carrying capacity: Measure 7.1A of the Northwest Power Planning Council's 1994 Fish and Wildlife Program. Report 1 of 4, Final report

    Neitzel, D.A.; Johnson, G.E.

    1996-05-01

    This report is one of four that the Pacific Northwest National Laboratory (PNNL) staff prepared to address Measure 7.1A in the Northwest Power Planning Council's (Council) Fish and Wildlife Program (Program) dated december 1994 (NPPC 1994). Measure 7.1A calls for the Bonneville Power Administration (BPA) to fund an evaluation of salmon survival, ecology, carrying capacity, and limiting factors in freshwater, estuarine, and marine habitats. Additionally, the Measure asks for development of a study plan based on critical uncertainties and research needs identified during the evaluation. This report deals with the evaluation of carrying capacity. It describes the analysis of different views of capacity as it relates to salmon survival and abundance. The report ends with conclusions and recommendations for studying carrying capacity

  15. Evaluation of Carrying Capacity : Measure 7.1A of the Northwest Power Planning Council`s 1994 Fish and Wildlife Program : Report 1 of 4, Final Report.

    Neitzel, Duane A.; Johnson, Gary E.

    1996-05-01

    This report is one of four that the Pacific Northwest National Laboratory (PNNL) staff prepared to address Measure 7.1A in the Northwest Power Planning Council's (Council) Fish and Wildlife Program (Program) dated december 1994 (NPPC 1994). Measure 7.1A calls for the Bonneville Power Administration (BPA) to fund an evaluation of salmon survival, ecology, carrying capacity, and limiting factors in freshwater, estuarine, and marine habitats. Additionally, the Measure asks for development of a study plan based on critical uncertainties and research needs identified during the evaluation. This report deals with the evaluation of carrying capacity. It describes the analysis of different views of capacity as it relates to salmon survival and abundance. The report ends with conclusions and recommendations for studying carrying capacity.

  16. Homogenate-assisted Vacuum-powered Bubble Extraction of Moso Bamboo Flavonoids for On-line Scavenging Free Radical Capacity Analysis.

    Sun, Yinnan; Yang, Kui; Cao, Qin; Sun, Jinde; Xia, Yu; Wang, Yinhang; Li, Wei; Ma, Chunhui; Liu, Shouxin

    2017-07-11

    A homogenate-assisted vacuum-powered bubble extraction (HVBE) method using ethanol was applied for extraction of flavonoids from Phyllostachys pubescens (P. pubescens) leaves. The mechanisms of homogenate-assisted extraction and vacuum-powered bubble generation were discussed in detail. Furthermore, a method for the rapid determination of flavonoids by HPLC was established. HVBE followed by HPLC was successfully applied for the extraction and quantification of four flavonoids in P. pubescens , including orientin, isoorientin, vitexin, and isovitexin. This method provides a fast and effective means for the preparation and determination of plant active components. Moreover, the on-line antioxidant capacity, including scavenging positive ion and negative ion free radical capacity of different fractions from the bamboo flavonoid extract was evaluated. Results showed that the scavenging DPPH ˙ free radical capacity of vitexin and isovitexin was larger than that of isoorientin and orientin. On the contrary, the scavenging ABTS⁺ ˙ free radical capacity of isoorientin and orientin was larger than that of vitexin and isovitexin.

  17. Optimal Planning Method of On-load Capacity Regulating Distribution Transformers in Urban Distribution Networks after Electric Energy Replacement Considering Uncertainties

    Yu Su

    2018-06-01

    Full Text Available Electric energy replacement is the umbrella term for the use of electric energy to replace oil (e.g., electric automobiles, coal (e.g., electric heating, and gas (e.g., electric cooking appliances, which increases the electrical load peak, causing greater valley/peak differences. On-load capacity regulating distribution transformers have been used to deal with loads with great valley/peak differences, so reasonably replacing conventional distribution transformers with on-load capacity regulating distribution transformers can effectively cope with load changes after electric energy replacement and reduce the no-load losses of distribution transformers. Before planning for on-load capacity regulating distribution transformers, the nodal effective load considering uncertainties within the life cycle after electric energy replacement was obtained by a Monte Carlo method. Then, according to the loss relation between on-load capacity regulating distribution transformers and conventional distribution transformers, three characteristic indexes of annual continuous apparent power curve and replacement criteria for on-load capacity regulating distribution transformers were put forward in this paper, and a set of distribution transformer replaceable points was obtained. Next, based on cost benefit analysis, a planning model of on-load capacity regulating distribution transformers which consists of investment profitability index within the life cycle, investment cost recouping index and capacity regulating cost index was put forward. The branch and bound method was used to solve the planning model within replaceable point set to obtain upgrading and reconstruction scheme of distribution transformers under a certain investment. Finally, planning analysis of on-load capacity regulating distribution transformers was carried out for electric energy replacement points in one urban distribution network under three scenes: certain load, uncertain load and nodal

  18. Influence of Laccase and Tyrosinase on the Antioxidant Capacity of Selected Phenolic Compounds on Human Cell Lines

    Matthias Riebel

    2015-09-01

    Full Text Available Polyphenolic compounds affect the color, odor and taste of numerous food products of plant origin. In addition to the visual and gustatory properties, they serve as radical scavengers and have antioxidant effects. Polyphenols, especially resveratrol in red wine, have gained increasing scientific and public interest due to their presumptive beneficial impact on human health. Enzymatic oxidation of phenolic compounds takes place under the influence of polyphenol oxidases (PPO, including tyrosinase and laccase. Several studies have demonstrated the radical scavenger effect of plants, food products and individual polyphenols in vitro, but, apart from resveratrol, such impact has not been proved in physiological test systems. Furthermore, only a few data exist on the antioxidant capacities of the enzymatic oxidation products of phenolic compounds generated by PPO. We report here first results about the antioxidant effects of phenolic substances, before and after oxidation by fungal model tyrosinase and laccase. In general, the common chemical 2,2-diphenyl-1-picrylhydrazyl assay and the biological tests using two different types of cell cultures (monocytes and endothelial cells delivered similar results. The phenols tested showed significant differences with respect to their antioxidant activity in all test systems. Their antioxidant capacities after enzymatic conversion decreased or increased depending on the individual PPO used.

  19. Essays in energy policy and planning modeling under uncertainty: Value of information, optimistic biases, and simulation of capacity markets

    Hu, Ming-Che

    Optimization and simulation are popular operations research and systems analysis tools for energy policy modeling. This dissertation addresses three important questions concerning the use of these tools for energy market (and electricity market) modeling and planning under uncertainty. (1) What is the value of information and cost of disregarding different sources of uncertainty for the U.S. energy economy? (2) Could model-based calculations of the performance (social welfare) of competitive and oligopolistic market equilibria be optimistically biased due to uncertainties in objective function coefficients? (3) How do alternative sloped demand curves perform in the PJM capacity market under economic and weather uncertainty? How does curve adjustment and cost dynamics affect the capacity market outcomes? To address the first question, two-stage stochastic optimization is utilized in the U.S. national MARKAL energy model; then the value of information and cost of ignoring uncertainty are estimated for three uncertainties: carbon cap policy, load growth and natural gas prices. When an uncertainty is important, then explicitly considering those risks when making investments will result in better performance in expectation (positive expected cost of ignoring uncertainty). Furthermore, eliminating the uncertainty would improve strategies even further, meaning that improved forecasts of future conditions are valuable ( i.e., a positive expected value of information). Also, the value of policy coordination shows the difference between a strategy developed under the incorrect assumption of no carbon cap and a strategy correctly anticipating imposition of such a cap. For the second question, game theory models are formulated and the existence of optimistic (positive) biases in market equilibria (both competitive and oligopoly markets) are proved, in that calculated social welfare and producer profits will, in expectation, exceed the values that will actually be received

  20. Interleukin 1β, tumor necrosis factor-α and interleukin 6 decreas nuclear thyroid hormone receptor capacity in a liver cell line

    Wolf, M.; Hansen, N.; Greten, H.

    1994-01-01

    Many of the acute inflammatory responses in critical illness are mediated by tumor necrosis factor-α (TNTF-α), interleukin 1β (IL-1β) and interleukin 6 (IL-6). Furthermore, these cytokines are involved in mediating the characteristic changes of thyroid function during acute disease known as non-thyroidal illness. In the present studies the authors investigated in vitro whether TNF-α, IL-1β and IL-6 modify nuclear thyroid hormone receptor (TR) capacity and/or affinity. Regulation of TR synthesis was studied in the human hepatoma cell line Hep-G2. Subconfluent cells were incubated with recombinant cytokines in serum-free medium. Nuclear extracts were prepared by high-salt extraction of cell nuclei. Binding assays were performed with [ 125 I]-triiodothyronine; bound and free hormone were separated by filtration. Interleukin 1β decreased TR capacity in a dose-dependent manner. Compared with unstimulated cells, the TR capacity was reduced to 87.9 ± 3.9% after incubation with 0.1, 1.0 and 100 μg/l IL-1β, respectively. Interleukin 6 and TNF-α significantly reduced receptor capacity only at concentrations of 10μg/l or higher and the magnitude of the reduction was lower than with IL-1β. The TR capacity was reduced to 81.2 ± 2.3% and 83.2 ± 6.6% after stimulation with 10μg/l IL-6 or TNF-α, respectively. TR affinity was not altered significantly after stimulation with any of the cytokines. 44 refs., 4 figs

  1. Future Marine Polar Research Capacities - Science Planning and Research Services for a Multi-National Research Icebreaker

    Biebow, N.; Lembke-Jene, L.; Wolff-Boenisch, B.; Bergamasco, A.; De Santis, L.; Eldholm, O.; Mevel, C.; Willmott, V.; Thiede, J.

    2011-12-01

    Despite significant advances in Arctic and Antarctic marine science over the past years, the polar Southern Ocean remains a formidable frontier due to challenging technical and operational requirements. Thus, key data and observations from this important region are still missing or lack adequate lateral and temporal coverage, especially from time slots outside optimal weather seasons and ice conditions. These barriers combined with the obligation to efficiently use financial resources and funding for expeditions call for new approaches to create optimally equipped, but cost-effective infrastructures. These must serve the international science community in a dedicated long-term mode and enable participation in multi-disciplinary expeditions, with secured access to optimally equipped marine platforms for world-class research in a wide range of Antarctic science topics. The high operational and technical performance capacity of a future joint European Research Icebreaker and Deep-sea Drilling Vessel (the AURORA BOREALIS concept) aims at integrating still separately operating national science programmes with different strategic priorities into joint development of long-term research missions with international cooperation both in Arctic and Antarctica. The icebreaker is planned to enable, as a worldwide first, autonomous year-round operations in the central Arctic and polar Southern Ocean, including severest ice conditions in winter, and serving all polar marine disciplines. It will facilitate the implementation of atmospheric, oceanographic, cryospheric or geophysical observatories for long-term monitoring of the polar environment. Access to the biosphere and hydrosphere e.g. beneath ice shelves or in remote regions is made possible by acting as advanced deployment platform for instruments, robotic and autonomous vehicles and ship-based air operations. In addition to a report on the long-term strategic science and operational planning objectives, we describe foreseen

  2. Call Center Capacity Planning

    Nielsen, Thomas Bang

    in order to relate the results to the service levels used in call centers. Furthermore, the generic nature of the approximation is demonstrated by applying it to a system incorporating a dynamic priority scheme. In the last paper Optimization of overflow policies in call centers, overflows between agent......The main topics of the thesis are theoretical and applied queueing theory within a call center setting. Call centers have in recent years become the main means of communication between customers and companies, and between citizens and public institutions. The extensively computerized infrastructure...... in modern call centers allows for a high level of customization, but also induces complicated operational processes. The size of the industry together with the complex and labor intensive nature of large call centers motivates the research carried out to understand the underlying processes. The customizable...

  3. Evolutionary Optimization for the Number and Capacity of Surge Tanks and Pipeline Diameters in a Transmission Line

    Gholam Reza Talebzadeh Sarvestani

    2006-09-01

    Full Text Available Controlling the unsteady effects of fluid flow (water hammer is one of the most important monitoring factors for structural protection of transmission pipelines. These effects are controlled by surge tanks, air chambers, pressure relief valves, and check valves. Generally, the critical points are detected by simulating the unsteady flow of the fluid, and accordingly, optimum positioning of the control devices is decided. Among the search methods, Genetic Algorithm (GA is an effective and robust method to solve highly complex optimization problems. Here, for the first time, GA coupled with an unsteady flow simulator is used to optimize the number and capacity of surge tanks in a pipeline system. In addition, the pipeline diameters are optimized for their best performance.

  4. Engineering Task Plan for Hose-In-Hose Transfer Lines for the Interim Stabilization Program

    TORRES, T.D.

    2000-01-01

    The document is the Engineering Task Plan for the engineering, design services, planning, project integration and management support for the design, modification, installation and testing of an over ground transfer (OGT) system to support the interim stabilization of S/SX and U Tank Farms

  5. Engineering Task Plan for Hose-In-Hose Transfer Lines for the Interim Stabilization Program

    RUNG, M.P.

    2000-01-01

    This document is the Engineering Task Plan for the engineering, design services, planning, project integration and management support for the design, modification, installation and testing of an over ground transfer (OGT) system to support the interim stabilization of nine tanks in the 241-S/SX Tank Farms

  6. Multi-objective Analysis for a Sequencing Planning of Mixed-model Assembly Line

    Shimizu, Yoshiaki; Waki, Toshiya; Yoo, Jae Kyu

    Diversified customer demands are raising importance of just-in-time and agile manufacturing much more than before. Accordingly, introduction of mixed-model assembly lines becomes popular to realize the small-lot-multi-kinds production. Since it produces various kinds on the same assembly line, a rational management is of special importance. With this point of view, this study focuses on a sequencing problem of mixed-model assembly line including a paint line as its preceding process. By taking into account the paint line together, reducing work-in-process (WIP) inventory between these heterogeneous lines becomes a major concern of the sequencing problem besides improving production efficiency. Finally, we have formulated the sequencing problem as a bi-objective optimization problem to prevent various line stoppages, and to reduce the volume of WIP inventory simultaneously. Then we have proposed a practical method for the multi-objective analysis. For this purpose, we applied the weighting method to derive the Pareto front. Actually, the resulting problem is solved by a meta-heuristic method like SA (Simulated Annealing). Through numerical experiments, we verified the validity of the proposed approach, and discussed the significance of trade-off analysis between the conflicting objectives.

  7. Station Capacity

    Landex, Alex

    2011-01-01

    the probability of conflicts and the minimum headway times into account. The last method analyzes how optimal platform tracks are used by examining the arrival and departure pattern of the trains. The developed methods can either be used separately to analyze specific characteristics of the capacity of a station......Stations are often limiting the capacity of railway networks. This is due to extra need of tracks when trains stand still, trains turning around, and conflicting train routes. Although stations are often the capacity bottlenecks, most capacity analysis methods focus on open line capacity. Therefore...... for platform tracks and the probability that arriving trains will not get a platform track immediately at arrival. The third method is a scalable method that analyzes the conflicts in the switch zone(s). In its simplest stage, the method just analyzes the track layout while the more advanced stages also take...

  8. An Examination of the Predictive Relationships of Self-Evaluation Capacity and Staff Competency on Strategic Planning in Hong Kong Aided Secondary Schools

    Cheng, Eric C. K.

    2011-01-01

    This article aims to examine the predictive relationships of self-evaluation capacity and staff competency on the effect of strategic planning in aided secondary schools in Hong Kong. A quantitative questionnaire survey was compiled to collect data from principals of the participating schools. Confirmatory factor analysis and reliability tests…

  9. Temperature induces significant changes in both glycolytic reserve and mitochondrial spare respiratory capacity in colorectal cancer cell lines

    Mitov, Mihail I., E-mail: m.mitov@uky.edu [Markey Cancer Center, University of Kentucky, Lexington, KY 40536 (United States); Harris, Jennifer W. [Department of Surgery, University of Kentucky, Lexington, KY 40506 (United States); Alstott, Michael C.; Zaytseva, Yekaterina Y. [Markey Cancer Center, University of Kentucky, Lexington, KY 40536 (United States); Evers, B. Mark [Markey Cancer Center, University of Kentucky, Lexington, KY 40536 (United States); Department of Surgery, University of Kentucky, Lexington, KY 40506 (United States); Butterfield, D. Allan [Markey Cancer Center, University of Kentucky, Lexington, KY 40536 (United States); Department of Chemistry, University of Kentucky, Lexington, KY 40506 (United States)

    2017-05-15

    Thermotherapy, as a method of treating cancer, has recently attracted considerable attention from basic and clinical investigators. A number of studies and clinical trials have shown that thermotherapy can be successfully used as a therapeutic approach for various cancers. However, the effects of temperature on cancer bioenergetics have not been studied in detail with a real time, microplate based, label-free detection approach. This study investigates how changes in temperature affect the bioenergetics characteristics (mitochondrial function and glycolysis) of three colorectal cancer (CRC) cell lines utilizing the Seahorse XF96 technology. Experiments were performed at 32 °C, 37 °C and 42 °C using assay medium conditions and equipment settings adjusted to produce equal oxygen and pH levels ubiquitously at the beginning of all experiments. The results suggest that temperature significantly changes multiple components of glycolytic and mitochondrial function of all cell lines tested. Under hypothermia conditions (32 °C), the extracellular acidification rates (ECAR) of CRC cells were significantly lower compared to the same basal ECAR levels measured at 37 °C. Mitochondrial stress test for SW480 cells at 37 °C vs 42 °C demonstrated increased proton leak while all other OCR components remained unchanged (similar results were detected also for the patient-derived xenograft cells Pt.93). Interestingly, the FCCP dose response at 37 °C vs 42 °C show significant shifts in profiles, suggesting that single dose FCCP experiments might not be sufficient to characterize the mitochondrial metabolic potential when comparing groups, conditions or treatments. These findings provide valuable insights for the metabolic and bioenergetic changes of CRC cells under hypo- and hyperthermia conditions that could potentially lead to development of better targeted and personalized strategies for patients undergoing combined thermotherapy with chemotherapy.

  10. Temperature induces significant changes in both glycolytic reserve and mitochondrial spare respiratory capacity in colorectal cancer cell lines

    Mitov, Mihail I.; Harris, Jennifer W.; Alstott, Michael C.; Zaytseva, Yekaterina Y.; Evers, B. Mark; Butterfield, D. Allan

    2017-01-01

    Thermotherapy, as a method of treating cancer, has recently attracted considerable attention from basic and clinical investigators. A number of studies and clinical trials have shown that thermotherapy can be successfully used as a therapeutic approach for various cancers. However, the effects of temperature on cancer bioenergetics have not been studied in detail with a real time, microplate based, label-free detection approach. This study investigates how changes in temperature affect the bioenergetics characteristics (mitochondrial function and glycolysis) of three colorectal cancer (CRC) cell lines utilizing the Seahorse XF96 technology. Experiments were performed at 32 °C, 37 °C and 42 °C using assay medium conditions and equipment settings adjusted to produce equal oxygen and pH levels ubiquitously at the beginning of all experiments. The results suggest that temperature significantly changes multiple components of glycolytic and mitochondrial function of all cell lines tested. Under hypothermia conditions (32 °C), the extracellular acidification rates (ECAR) of CRC cells were significantly lower compared to the same basal ECAR levels measured at 37 °C. Mitochondrial stress test for SW480 cells at 37 °C vs 42 °C demonstrated increased proton leak while all other OCR components remained unchanged (similar results were detected also for the patient-derived xenograft cells Pt.93). Interestingly, the FCCP dose response at 37 °C vs 42 °C show significant shifts in profiles, suggesting that single dose FCCP experiments might not be sufficient to characterize the mitochondrial metabolic potential when comparing groups, conditions or treatments. These findings provide valuable insights for the metabolic and bioenergetic changes of CRC cells under hypo- and hyperthermia conditions that could potentially lead to development of better targeted and personalized strategies for patients undergoing combined thermotherapy with chemotherapy.

  11. Status and Plans for the SPS to LHC Beam Transfer Lines TI 2 and TI 8

    Goddard, B; Risselada, Thys

    2004-01-01

    Beam transfer from the CERN Super Proton Synchrotron (SPS) to the Large Hadron Collider (LHC) will be done through the two transfer lines TI 2 and TI 8, presently under construction, with a combined length of about 5.6 km. The final layout, optics design and correction scheme for these lines will be presented. The requirement of simultaneously matching their geometry and optics with that of the LHC will be treated, including the methodology for alignment of the elements along the line and a proposed solution in the final matching section. After the commissioning of the short transfer line TT40 just upstream of TI 8 in 2003, beam tests of the whole of TI 8 are scheduled for autumn 2004, with the aim to validate many of the new features and mechanisms involved in the future control and operation of these lines. The status of the installation will be described, comprising the progress with infrastructure, services and line elements. An outlook will be given for the work remaining until 2007.

  12. Effect of radiation on the expression of E-cadherin and α-catenin and invasive capacity in human lung cancer cell line in vitro

    Akimoto, Tetsuo; Mitsuhashi, Norio; Saito, Yoshihiro; Ebara, Takeshi; Niibe, Hideo

    1998-01-01

    Purpose: To investigate the effect of radiation on E-cadherin and α-catenin expression in a human lung cancer cell line, and also evaluate invasive capacity in the membrane invasion culture system using the Boyden Chamber. Materials and Methods: The immunoblot and immunofluorescence analyses were performed using the human lung cancer cell line A549 to examine altered expression of E-cadherin and α-catenin after irradiation. We also compared invasive capacity of untreated cells with that of irradiated cells. Results: Immunoblot analysis revealed that the expression of E-cadherin increased after irradiation. In a time-course analysis, the expression was increased 6 h after irradiation with 10 Gy and reached its peak level at 24 h, being 2.3 times the control value, whereas expression at 1 and 3 h after irradiation was almost equivalent to that of the control. A slight increase in expression was observed after irradiation of 2 Gy and the expression reached peak levels after 5 Gy. After fractionated irradiation, the increase in expression of both E-cadherin and α-catenin was observed, and the alteration of α-catenin was more prominent than that after a single irradiation of the same total dose. In the immunofluorescence study for E-cadherin antibody analyzed by confocal laser scanning microscopy, increased intensity in irradiated cells produced as a nondisrupted and continuous line at cell-cell contact sites. In an invasive assay, the number of migrated cells in irradiated cells after a dose of 5 and 10 Gy was reduced significantly compared to untreated cells. Conclusion: The results indicate that irradiation of A549 increased the expression of E-cadherin, possibly preserving their functional property

  13. Exposure to runoff from coal-tar-sealed pavement induces genotoxicity and impairment of DNA repair capacity in the RTL-W1 fish liver cell line.

    Kienzler, Aude; Mahler, Barbara J; Van Metre, Peter C; Schweigert, Nathalie; Devaux, Alain; Bony, Sylvie

    2015-07-01

    Coal-tar-based (CTB) sealcoat, frequently applied to parking lots and driveways in North America, contains elevated concentrations of polycyclic aromatic hydrocarbons (PAHs) and related compounds. The RTL-W1 fish liver cell line was used to investigate two endpoints (genotoxicity and DNA-repair-capacity impairment) associated with exposure to runoff from asphalt pavement with CTB sealcoat or with an asphalt-based sealcoat hypothesized to contain about 7% CTB sealcoat (AS-blend). Genotoxic potential was assessed by the Formamido pyrimidine glycosylase (Fpg)-modified comet assay for 1:10 and 1:100 dilutions of runoff samples collected from 5 h to 36 d following sealcoat application. DNA-repair capacity was assessed by the base excision repair comet assay for 1:10 dilution of samples collected 26 h and 36 d following application. Both assays were run with and without co-exposure to ultraviolet-A radiation (UVA). With co-exposure to UVA, genotoxic effects were significant for both dilutions of CTB runoff for three of four sample times, and for some samples of AS-blend runoff. Base excision repair was significantly impaired for CTB runoff both with and without UVA exposure, and for AS-blend runoff only in the absence of UVA. This study is the first to investigate the effects of exposure to the complex mixture of chemicals in coal tar on DNA repair capacity. The results indicate that co-exposure to runoff from CT-sealcoated pavement and UVA as much as a month after sealcoat application has the potential to cause genotoxicity and impair DNA repair capacity. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Exposure to runoff from coal-tar-sealed pavement induces genotoxicity and impairment of DNA repair capacity in the RTL-W1 fish liver cell line

    Kienzler, Aude; Mahler, Barbara J.; Van Metre, Peter C.; Schweigert, Nathalie; Devaux, Alain; Bony, Sylvie

    2015-01-01

    Coal-tar-based (CTB) sealcoat, frequently applied to parking lots and driveways in North America, contains elevated concentrations of polycyclic aromatic hydrocarbons (PAHs) and related compounds. The RTL-W1 fish liver cell line was used to investigate two endpoints (genotoxicity and DNA-repair-capacity impairment) associated with exposure to runoff from asphalt pavement with CTB sealcoat or with an asphalt-based sealcoat hypothesized to contain about 7% CTB sealcoat (AS-blend). Genotoxic potential was assessed by the Formamido pyrimidine glycosylase (Fpg)-modified comet assay for 1:10 and 1:100 dilutions of runoff samples collected from 5 h to 36 d following sealcoat application. DNA-repair capacity was assessed by the base excision repair comet assay for 1:10 dilution of samples collected 26 h and 36 d following application. Both assays were run with and without co-exposure to ultraviolet-A radiation (UVA). With co-exposure to UVA, genotoxic effects were significant for both dilutions of CTB runoff for three of four sample times, and for some samples of AS-blend runoff. Base excision repair was significantly impaired for CTB runoff both with and without UVA exposure, and for AS-blend runoff only in the absence of UVA. This study is the first to investigate the effects of exposure to the complex mixture of chemicals in coal tar on DNA repair capacity. The results indicate that co-exposure to runoff from CT-sealcoated pavement and UVA as much as a month after sealcoat application has the potential to cause genotoxicity and impair DNA repair capacity.

  15. Problem in application carrying capacity approach for land allocation assessment in Indonesian municipal spatial planning: A case of Kutai Kartanegara Regency

    Wijaya, I. N. S.; Rahadi, B.; Lusiana, N.; Maulidina, I.

    2017-06-01

    Urbanization in many countries, such as Indonesia, is commonly appeared as a dynamic population of developed areas. It is followed with reducing rural uses of land for improving urban land uses such as housing, industry, infrastructure, etc. in response to the growth of population. One may not be sufficiently considered by the urban planners and the decision makers, urbanization also means escalation of natural resources consumption that should be supported by the natural capacity of the area. In this situation, balancing approach as carrying capacity calculation in spatial planning is needed for sustainability. Indonesian Spatial Planning Law 26/2007 has already expressed about the balance approach in the system. Moreover, it strictly regulates the assessment and the permission system in controlling land development, especially for the conversion. However, the reductions over the rural uses of land, especially agriculture, are continuously occurred. Concerning the planning approach, this paper aims to disclose common insufficiency of carrying capacity considerations in Indonesian spatial planning practice. This paper describes common calculation weaknesses in projecting area for the urban development by recalculating the actual gap between supply and demand of agriculture land areas. Here, municipal spatial plan of Kutai Kartanegara Regency is utilized as single sample case to discuss. As the result, the recalculation shows that: 1) there are serious deficit status of agriculture land areas in order to fulfil the demanded agriculture production for the existed population, 2) some calculation of agriculture production may be miss-interpreted because of insufficient explanation toward the productivity of each agriculture commodity.

  16. Jefferson Proving Ground, South of the Firing Line Health and Safety Plan, Volume 4

    1992-01-01

    .... The purpose of this Site Health and Safety Plan (SHSP) is to assign SECD personnel health and safety responsibilities, to prescribe mandatory operating procedures, and to establish personal-protective-equipment (PPE...

  17. Characterisation of Human Keratinocytes by Measuring Cellular Repair Capacity of UVB-Induced DNA Damage and Monitoring of Cytogenetic Changes in Melanoma Cell Lines

    Greinert, R.; Breibart, E.W.; Mitchell, D.; Smida, J.; Volkmer, B

    2000-07-01

    The molecular mechanisms for UV-induced photocarcinogenesis are far from being understood in detail, especially in the case of malignant melanoma of the skin. Nevertheless, it is known that deficiencies in cellular repair processes of UV-induced DNA damage (e.g. in the case of Xeroderma pigmentosum) represent important aetiological factors in the multistep development of skin cancer. The repair kinetics have therefore been studied of an established skin cell line (HaCaT), primary human keratinocytes, melanocytes and melanoma cell lines, using fluorescence microscopy and flow cytometry. Our data show a high degree of interindividual variability in cellular repair capacity for UV-induced DNA lesions, which might be due to individual differences in the degree of tolerable damage and/or the onsets of saturation of the enzymatic repair system. The cytogenetic analysis of melanoma cell lines, using spectral karyotyping (SKY) furthermore proves that malignant melanoma of the skin are characterised by high numbers of chromosomal aberrations. (author)

  18. The benefits of designing a stratification system for New York City pediatric intensive care units for use in regional surge capacity planning and management.

    Campbell, Christiana

    2010-08-01

    Accurate assessment of New York City (NYC) pediatric intensive care unit (PICU) resources and the ability to surge them during a disaster has been recognized as an important citywide emergency preparedness activity. However, while NYC hospitals with PICUs may be expected to surge in a disaster, few of them have detailed surge capacity plans. This will likely make it difficult for them to realize their full surge capacity both on individual and regional levels. If the pediatric resources that each NYC PICU hospital has can be identified prior to a disaster, this information can be used to both determine appropriate surge capacity goals for each PICU hospital and the additional resources needed to reach those goals. City agencies can then focus citywide planning efforts on making these resources available and more easily anticipate what a hospital will need during a disaster. Communication of this hospital information both prior to and during a surge situation will be aided by a stratification system familiar to both city planners and hospitals. The goal of this project was to design a NYC PICU surge stratification system that would aid physicians, hospitals and city agencies in regional surge capacity planning for critical pediatric patients. This goal was demonstrated through two objectives. The first identified major factors to consider when designing a stratification system. The second devised a preliminary system of PICU stratification based on clinical criteria and resources.

  19. Mobile-Source GHG Modeling Institutions and Capacities in China:Findings Based on Structured Interviews and On-Line Surveys

    Jiangping; ZHOU; Yin; WANG

    2014-01-01

    This paper provides an overview of practices of mobile-source greenhouse gas(GHG) modeling in China and related data sharing issues. It is based on structured phone interviews and two on-line surveys conducted in 2011 and finds that most cities have transportation-land use models but that few have mobile-source GHG models. A group of entities housed in the government have the strongest GHG modeling capacities and dominate the relevant consulting market. Data hoarding of public entities is the biggest barrier for entities without government ties to compete in the market. The reasons for data hoarding include government concerns over political implications of data release, a tradition of data hoarding, and a lack of confidence in reliability and accuracy of the data.

  20. Exposure to runoff from coal-tar-sealed pavement induces genotoxicity and impairment of DNA repair capacity in the RTL-W1 fish liver cell line

    Kienzler, Aude; Mahler, Barbara J.; Van Metre, Peter C.; Schweigert, Nathalie; Devaux, Alain; Bony, Sylvie

    2015-01-01

    Coal-tar-based (CTB) sealcoat, frequently applied to parking lots and driveways in North America, contains elevated concentrations of polycyclic aromatic hydrocarbons (PAHs) and related compounds. The RTL-W1 fish liver cell line was used to investigate two endpoints (genotoxicity and DNA-repair-capacity impairment) associated with exposure to runoff from asphalt pavement with CTB sealcoat or with an asphalt-based sealcoat hypothesized to contain about 7% CTB sealcoat (AS-blend). Genotoxic potential was assessed by the Formamido pyrimidine glycosylase (Fpg)-modified comet assay for 1:10 and 1:100 dilutions of runoff samples collected from 5 h to 36 d following sealcoat application. DNA-repair capacity was assessed by the base excision repair comet assay for 1:10 dilution of samples collected 26 h and 36 d following application. Both assays were run with and without co-exposure to ultraviolet-A radiation (UVA). With co-exposure to UVA, genotoxic effects were significant for both dilutions of CTB runoff for three of four sample times, and for some samples of AS-blend runoff. Base excision repair was significantly impaired for CTB runoff both with and without UVA exposure, and for AS-blend runoff only in the absence of UVA. This study is the first to investigate the effects of exposure to the complex mixture of chemicals in coal tar on DNA repair capacity. The results indicate that co-exposure to runoff from CT-sealcoated pavement and UVA as much as a month after sealcoat application has the potential to cause genotoxicity and impair DNA repair capacity. - Highlights: • Co-exposure to runoff from coal-tar-sealcoated pavement and UVA caused DNA damage. • Significant genotoxicity occurred with a 1:100 dilution of runoff. • Runoff collected up to 36 d following coal-tar-sealcoat application was genotoxic. • Exposure to runoff from sealed pavement impaired an important DNA repair pathway. • Repair capacity was impaired with a 1:10 dilution of runoff (1:100 not

  1. Exposure to runoff from coal-tar-sealed pavement induces genotoxicity and impairment of DNA repair capacity in the RTL-W1 fish liver cell line

    Kienzler, Aude, E-mail: aude.kienzler@entpe.fr [Université de Lyon, UMR LEHNA 5023, USC INRA, ENTPE, rue Maurice Audin, Vaulx-en-Velin F-69518 (France); Mahler, Barbara J., E-mail: bjmahler@usgs.gov [U.S. Geological Survey, 1505 Ferguson Lane, Austin, TX 78754 (United States); Van Metre, Peter C., E-mail: pcvanmet@usgs.gov [U.S. Geological Survey, 1505 Ferguson Lane, Austin, TX 78754 (United States); Schweigert, Nathalie [Université de Lyon, UMR LEHNA 5023, USC INRA, ENTPE, rue Maurice Audin, Vaulx-en-Velin F-69518 (France); Devaux, Alain, E-mail: alain.devaux@entpe.fr [Université de Lyon, UMR LEHNA 5023, USC INRA, ENTPE, rue Maurice Audin, Vaulx-en-Velin F-69518 (France); Bony, Sylvie, E-mail: bony@entpe.fr [Université de Lyon, UMR LEHNA 5023, USC INRA, ENTPE, rue Maurice Audin, Vaulx-en-Velin F-69518 (France)

    2015-07-01

    Coal-tar-based (CTB) sealcoat, frequently applied to parking lots and driveways in North America, contains elevated concentrations of polycyclic aromatic hydrocarbons (PAHs) and related compounds. The RTL-W1 fish liver cell line was used to investigate two endpoints (genotoxicity and DNA-repair-capacity impairment) associated with exposure to runoff from asphalt pavement with CTB sealcoat or with an asphalt-based sealcoat hypothesized to contain about 7% CTB sealcoat (AS-blend). Genotoxic potential was assessed by the Formamido pyrimidine glycosylase (Fpg)-modified comet assay for 1:10 and 1:100 dilutions of runoff samples collected from 5 h to 36 d following sealcoat application. DNA-repair capacity was assessed by the base excision repair comet assay for 1:10 dilution of samples collected 26 h and 36 d following application. Both assays were run with and without co-exposure to ultraviolet-A radiation (UVA). With co-exposure to UVA, genotoxic effects were significant for both dilutions of CTB runoff for three of four sample times, and for some samples of AS-blend runoff. Base excision repair was significantly impaired for CTB runoff both with and without UVA exposure, and for AS-blend runoff only in the absence of UVA. This study is the first to investigate the effects of exposure to the complex mixture of chemicals in coal tar on DNA repair capacity. The results indicate that co-exposure to runoff from CT-sealcoated pavement and UVA as much as a month after sealcoat application has the potential to cause genotoxicity and impair DNA repair capacity. - Highlights: • Co-exposure to runoff from coal-tar-sealcoated pavement and UVA caused DNA damage. • Significant genotoxicity occurred with a 1:100 dilution of runoff. • Runoff collected up to 36 d following coal-tar-sealcoat application was genotoxic. • Exposure to runoff from sealed pavement impaired an important DNA repair pathway. • Repair capacity was impaired with a 1:10 dilution of runoff (1:100 not

  2. Visual identification and similarity measures used for on-line motion planning of autonomous robots in unknown environments

    Martínez, Fredy; Martínez, Fernando; Jacinto, Edwar

    2017-02-01

    In this paper we propose an on-line motion planning strategy for autonomous robots in dynamic and locally observable environments. In this approach, we first visually identify geometric shapes in the environment by filtering images. Then, an ART-2 network is used to establish the similarity between patterns. The proposed algorithm allows that a robot establish its relative location in the environment, and define its navigation path based on images of the environment and its similarity to reference images. This is an efficient and minimalist method that uses the similarity of landmark view patterns to navigate to the desired destination. Laboratory tests on real prototypes demonstrate the performance of the algorithm.

  3. Building capacity in local government for integrated planning to increase physical activity: evaluation of the VicHealth MetroACTIVE program.

    Thomas, M M; Hodge, W; Smith, B J

    2009-12-01

    Integrated planning is a holistic approach to addressing the needs of local communities built on partnerships between those responsible for development, environmental quality and service provision. This study investigated the extent and key influences on the use of integrated planning to promote physical activity among six metropolitan councils in Melbourne Australia, which took part in the MetroACTIVE Project funded by the Victorian Health Promotion Foundation from 2005 to 2007. The evaluation entailed interviews conducted at the mid-term (N = 67) and completion (N = 50) of the project, and the review of relevant documents. Respondents included elected councillors, chief executive officers, officers from different council divisions and the project staff employed in each council. Three councils showed evidence of integrated planning for physical activity, whereas the remainder focused on the delivery of community participation programs. Leadership from senior management and an organizational culture that supported collaboration across council departments were prerequisites for integrated planning. Employment of a dedicated project officer with skills for engaging management and building partnerships within the organization was important. Barriers to integrated planning were a complex organization structure, high demands on the council due to a growing residential population and a poor climate among staff. Overall, integrated planning was found to be a viable approach for developing a coordinated approach to this issue involving the range of council services and functions. Ongoing strategies are needed to facilitate senior management commitment and organizational capacity for integrated planning, with leadership provided by departments responsible for infrastructure or corporate planning.

  4. Identification of differentially expressed genes in the oviduct of two rabbit lines divergently selected for uterine capacity using suppression subtractive hybridization.

    Ballester, M; Castelló, A; Peiró, R; Argente, M J; Santacreu, M A; Folch, J M

    2013-06-01

    Suppressive subtractive hybridization libraries from oviduct at 62 h post-mating of two lines of rabbits divergently selected for uterine capacity were generated to identify differentially expressed genes. A total of 438 singletons and 126 contigs were obtained by cluster assembly and sequence alignment of 704 expressed sequence tags (ESTs), of which 54% showed homology to known proteins of the non-redundant NCBI databases. Differential screening by dot blot validated 71 ESTs, of which 47 showed similarity to known genes. Transcripts of genes were functionally annotated in the molecular function and the biological process gene ontology categories using the BLAST2GO software and were assigned to reproductive developmental process, immune response, amino acid metabolism and degradation, response to stress and apoptosis terms. Finally, three interesting genes, PGR, HSD17B4 and ERO1L, were identified as overexpressed in the low line using RT-qPCR. Our study provides a list of candidate genes that can be useful to understanding the molecular mechanisms underlying the phenotypic differences observed in early embryo survival and development traits. © 2012 The Authors, Animal Genetics © 2012 Stichting International Foundation for Animal Genetics.

  5. Multi-agent System for Off-line Coordinated Motion Planning of Multiple Industrial Robots

    Shital S. Chiddarwar

    2011-03-01

    Full Text Available This article presents an agent based framework for coordinated motion planning of multiple robots. The emerging paradigm of agent based systems is implemented to address various issues related to safe and fast task execution when multiple robots share a common workspace. In the proposed agent based framework, each issue vital for coordinated motion planning of multiple robots and every robot participating in coordinated task is considered as an agent. The identified agents are interfaced with each other in order to incorporate the desired flexibility in the developed framework. This framework gives a complete strategy for determination of optimal trajectories of robots working in coordination with due consideration to their kinematic, dynamic and payload constraint. The complete architecture of the proposed framework and the detailed discussion on various modules are covered in this paper.

  6. Second Line of Defense Megaports Initiative Sustainment Plan - Port Klang Malaysia

    King, Curtis A.

    2009-09-29

    To reduce the risk of illicit trafficking of special nuclear and other radiological materials, the Megaports Initiative installs radiation detection systems at international seaports. Port Klang, Malaysia, is one such seaport identified by the Megaports Initiative as a key area to install equipment to accomplish the mission of preventing the acquisition and smuggling of materials that could be used to create weapons of mass destruction or radiological dispersal devices. Sustainability is a critical factor of all components of the Megaports Initiative. The sustainability plan is developed to assist the partner country in securing the technical, financial, and policy commitments required to develop and implement a country-specific strategy. A robust sustainability plan will define the long-term relationship between the U.S. Department of Energy and the Government of Malaysia as well as promote the ongoing proficient radiation detection system operations at Port Klang, Malaysia.

  7. Second Line of Defense Megaports Initiative Sustainment Plan - Port Klang Malaysia

    King, Curtis A.

    2009-01-01

    To reduce the risk of illicit trafficking of special nuclear and other radiological materials, the Megaports Initiative installs radiation detection systems at international seaports. Port Klang, Malaysia, is one such seaport identified by the Megaports Initiative as a key area to install equipment to accomplish the mission of preventing the acquisition and smuggling of materials that could be used to create weapons of mass destruction or radiological dispersal devices. Sustainability is a critical factor of all components of the Megaports Initiative. The sustainability plan is developed to assist the partner country in securing the technical, financial, and policy commitments required to develop and implement a country-specific strategy. A robust sustainability plan will define the long-term relationship between the U.S. Department of Energy and the Government of Malaysia as well as promote the ongoing proficient radiation detection system operations at Port Klang, Malaysia.

  8. A Generalized National Planning Approach for Admission Capacity in Higher Education: A Nonlinear Integer Goal Programming Model with a Novel Differential Evolution Algorithm.

    El-Qulity, Said Ali; Mohamed, Ali Wagdy

    2016-01-01

    This paper proposes a nonlinear integer goal programming model (NIGPM) for solving the general problem of admission capacity planning in a country as a whole. The work aims to satisfy most of the required key objectives of a country related to the enrollment problem for higher education. The system general outlines are developed along with the solution methodology for application to the time horizon in a given plan. The up-to-date data for Saudi Arabia is used as a case study and a novel evolutionary algorithm based on modified differential evolution (DE) algorithm is used to solve the complexity of the NIGPM generated for different goal priorities. The experimental results presented in this paper show their effectiveness in solving the admission capacity for higher education in terms of final solution quality and robustness.

  9. SU-E-J-92: On-Line Cone Beam CT Based Planning for Emergency and Palliative Radiation Therapy

    Held, M; Morin, O; Pouliot, J [UC San Francisco, San Francisco, CA (United States)

    2014-06-01

    Purpose: To evaluate and develop the feasibility of on-line cone beam CT based planning for emergency and palliative radiotherapy treatments. Methods: Subsequent to phantom studies, a case library of 28 clinical megavoltage cone beam CT (MVCBCT) was built to assess dose-planning accuracies on MVCBCT for all anatomical sites. A simple emergency treatment plan was created on the MVCBCT and copied to its reference CT. The agreement between the dose distributions of each image pair was evaluated by the mean dose difference of the dose volume and the gamma index of the central 2D axial plane. An array of popular urgent and palliative cases was also evaluated for imaging component clearance and field-of-view. Results: The treatment cases were categorized into four groups (head and neck, thorax/spine, pelvis and extremities). Dose distributions for head and neck treatments were predicted accurately in all cases with a gamma index of >95% for 2% and 2 mm criteria. Thoracic spine treatments had a gamma index as low as 60% indicating a need for better uniformity correction and tissue density calibration. Small anatomy changes between CT and MVCBCT could contribute to local errors. Pelvis and sacral spine treatment cases had a gamma index between 90% and 98% for 3%/3 mm criteria. The limited FOV became an issue for large pelvis patients. Imaging clearance was difficult for cases where the tumor was positioned far off midline. Conclusion: The MVCBCT based dose planning and delivery approach is feasible in many treatment cases. Dose distributions for head and neck patients are unrestrictedly predictable. Some FOV restrictions apply to other treatment sites. Lung tissue is most challenging for accurate dose calculations given the current imaging filters and corrections. Additional clinical cases for extremities need to be included in the study to assess the full range of site-specific planning accuracies. This work is supported by Siemens.

  10. Second Line of Defense Megaports Initiative Operational Testing and Evaluation Plan Colon Container Terminal (CCT) Panama

    Newhouse, Robert N.

    2010-01-01

    Report on the Operational Testing and Evaluation to validate and baseline an operable system that meets the Second Line of Defense (SLD) mission requirements. An SLD system is defined as the detection technology and associated equipment, the system operators from the host country, the standard operating procedures (SOPs), and other elements such as training and maintenance which support long-term system sustainment. To this end, the activities conducted during the OT&E phase must demonstrate that the Megaports System can be operated effectively in real-time by Panama Direccion General de Aduanas (DGA Panama Customs) personnel to the standards of the U.S. Department of Energy/National Nuclear Security Administration (DOE/NNSA).

  11. On-line trajectory planning of time-jerk optimal for robotic arms

    Nadir Bendali

    2016-09-01

    Full Text Available A method based on the computation of the time intervals of the knots for time-jerk optimal planning under kinematic constraints of robot manipulators in predefined operations is described in this paper. In order to ensure that the resulting trajectory is smooth enough, a cost function containing a term proportional to the integral of the squared jerk (defined as the derivative of the acceleration along the trajectory is considered. Moreover, a second term, proportional to the total execution time, is added to the expression of the cost function. A Cubic Spline functions are then used to compose overall trajectory. This method can meet the requirements of a short execution time and low arm vibration of the manipulator and the simulation provides good results.

  12. Tourism Planning and Design Based on the Environmental Carrying Capacity%基于环境承载力的旅游规划设计

    冀慧萍

    2015-01-01

    旅游的发展必然会对环境造成一定的影响,如何在发展旅游与保护环境之间取得平衡,是旅游规划设计中必须考虑的一个焦点问题. 环境承载能力又称环境容量,基于环境承载力进行旅游规划设计,能很好地确保旅游与环境间的和谐发展. 笔者对环境承载力进行了简要概述,提出了基于环境自洁能力、基于环境再生能力、基于生态足迹的旅游环境承载力的计算方法. 就基于环境承载能力的旅游规划设计进行了探讨,对地区旅游业的可持续发展、旅游资源的开发和调整、旅游环境的保护具有重要意义.%The development of tourism causes certain effect on the environment, and how to achieve a balance between tourism development and environmental protection is a focus problem, which in the tourism planning and design must be considered.Environmental carrying capacity is also called the environment capacity, tourism planning and design based on the environmental carrying capacity can ensure the harmonious development between tourism and environment.In this pa-per, tourism planning and design based on the environmental carrying capacity are discussed, which has positive signifi-cance for the sustainable development of regional tourism experience, the development of tourism resources and the adjust-ment, the protection of tourism environment .

  13. Assembly Line Productivity Assessment by Comparing Optimization-Simulation Algorithms of Trajectory Planning for Industrial Robots

    Francisco Rubio

    2015-01-01

    Full Text Available In this paper an analysis of productivity will be carried out from the resolution of the problem of trajectory planning of industrial robots. The analysis entails economic considerations, thus overcoming some limitations of the existing literature. Two methodologies based on optimization-simulation procedures are compared to calculate the time needed to perform an industrial robot task. The simulation methodology relies on the use of robotics and automation software called GRASP. The optimization methodology developed in this work is based on the kinematics and the dynamics of industrial robots. It allows us to pose a multiobjective optimization problem to assess the trade-offs between the economic variables by means of the Pareto fronts. The comparison is carried out for different examples and from a multidisciplinary point of view, thus, to determine the impact of using each method. Results have shown the opportunity costs of non using the methodology with optimized time trajectories. Furthermore, it allows companies to stay competitive because of the quick adaptation to rapidly changing markets.

  14. Plans for future on-line access to the historical astronomical literature through the Astrophysics Data System.

    Eichhorn, G.; Kurtz, M. J.; Coletti, D.

    1997-09-01

    The NASA Astrophysics Data System provides access to about 1 million abstracts and 50,000 journal articles. This service is funded by NASA and is accessible world-wide through the World Wide Web free without restrictions at: http://adswww.harvard.edu We currently have on-line journals starting with 1975. We plan to extend the coverage for the journals and also include scans from observatory publications in our database. Eventually we plan to provide access to scans of the complete journal literature and as much observatory literature as possible. In order to accomplish this, we have started discussions with the preservation group at the Harvard University Library. Harvard University Library, together with the Library at the Center for Astrophysics is in the process of microfilming their collection of observatory publications. We are working together with this project to prepare for scanning the microfilms and make these scans available through the ADS. We are also collecting older journals and preparing them for scanning. We already have the Monthly Notices of the Royal Astronomical Society in hand from Volume 1, and have been promised a large part of the Astronomische Nachrichten prior to 1945. We will start scanning these volumes soon. All volumes that can be fed automatically through the scanning machine should be scanned and put on-line within the next 6 - 12 months. In order to scan volumes that are too brittle, we need additional funding. We hope to obtain additional funding to cover such scanning for 1998. In order to cover more of the astronomical literature, we need donations of astronomical literature. We have a web page that lists the volumes that we need so we can scan them. If you have any of these journals (or other astronomical literature), please contact us. the web page is at: http://adshome.harvard.edu/pubs/missing_journals.html We would appreciate any contributions, even smaller sets, since it will be more and more difficult to find complete sets.

  15. Project W-314 specific test and evaluation plan for SN-635 transfer line (241-AY-01A to 241-AY-02A) and SN-633 transfer line tie in

    Hays, W.H.

    1998-01-01

    This Specific Test and Evaluation Plan (STEP) defines the test and evaluation activities encompassing the installation of the SN-635 transfer line for the W-314 Project. The purpose of this Specific Test and Evaluation Plan (STEP) is to provide a detailed written plan for the systematic testing of modifications made by the addition of the SN-635 transfer line and the tie in of SN-633 to the AY-02A pit by the W-314 Project. The STEP develops the outline for test procedures that verify the system's performance to the established Project design criteria. The STEP is a lower tier document based on the W-314 Test and Evaluation Plan (TEP)

  16. Building Adaptive Capacity in Changing Social-Ecological Systems: Integrating Knowledge in Communal Land-Use Planning in the Peruvian Amazon

    Lily O. Rodríguez

    2018-02-01

    Full Text Available Building resilient sustainable social-ecological systems (SES requires communities to enhance their adaptive capacities. Communal participative land-use planning (Zonificación Participativa Comunal—ZPC is a tool designed for communities to integrating local and scientific knowledge to sustainably organize and manage their SES. Between 2006 and 2011, a ZPC was developed with communities in the buffer zone of Cordillera Azul National Park (Peru, where rapid demographic changes are converting pre-montane seasonally dry forest into agricultural land. Herein, we analyse how the ZPC enhanced adaptive capacity, enabling the SES to cope with environmental, political and economic changes. Based on qualitative, semi-structured interviews, communities are analysed along their capacities in the dimensions social capital, learning, adaptive management and governance. An analysis of yearly high-resolution forest cover data supports our findings. Deforestation activities in biologically sensitive zones decreased rapidly during the time of the ZPC implementation. We find that particularly the long-term presence of the bridging institution and the continuous testing and reflection of the integrated “hybrid knowledge” enabled communities to develop adaptive capacities. The analysis of ZPC our results reveals the enabling conditions for promoting the learning process to develop a sustainable land-use management in the context of migration and rapid changes.

  17. The capacities of institutions for the integration of ecosystem services in coastal strategic planning: The case of Jiaozhou Bay

    Li, Ruiqian; Li, Yongfu; Woltjer, Johan; van den Brink, Margo

    2015-01-01

    This paper explains how the practice of integrating ecosystem-service thinking (i.e., ecological benefits for human beings) and institutions (i.e., organisations, policy rules) is essential for coastal spatial planning. Adopting an integrated perspective on ecosystem services (ESs) both helps

  18. CDMA systems capacity engineering

    Kim, Kiseon

    2004-01-01

    This new hands-on resource tackles capacity planning and engineering issues that are crucial to optimizing wireless communication systems performance. Going beyond the system physical level and investigating CDMA system capacity at the service level, this volume is the single-source for engineering and analyzing systems capacity and resources.

  19. La "capacidad vial" del plan regulador chileno, ¿es lo suficientemente buena para dar forma a un entorno edificado sostenible?/ The "road capacity" of the chilean master plan is it good enough for shaping a sustainable built environment?

    Cárdenas Jirón, Luz Alicia

    2000-03-01

    Full Text Available The "road capacity" of the Chilean Master Plan is a tool developed to measure the capacity of streets in terms of supporting the size of vehicle flow. This tool considers topics such as land use, population density and street width. The purpose of this technique is to incorporate it to the Master Plan, as a town planning instrument, so as to cope with traffic forecasting and congestion. However, the technique does not embrace any sustainability concept, this is due to a disregard of any district ´s social or environmental needs. Therefore a sustainable urban development would doubtfully be reached. It is argued that some other approaches are required for shaping a sustainable built environment in which it is understood that the streets are a public space for people rather than a platform for moving vehicles only. This means, to promote accessibility as well as mobility. In this paper the author reviews borrowed concepts such as "carrying capacity" and "environmental capacity" from bioregionalist and ecological disciplines using a case study in outskirts of Santiago´s metro area./La "capacidad vial" del Plan Regulador chileno es una herramienta desarrollada para medir la capacidad de las calles en términos de apoyar el tamaño del flujo de vehículos. Esta herramienta considera temas como el uso de la tierra, la densidad de población y ancho de la calle. El propósito de esta técnica es su incorporación al Plan Maestro, como un instrumento de planificación de la ciudad, con el fin de hacer frente a la previsión del tráfico y la congestión. Sin embargo, la técnica no incluye ningún concepto de sostenibilidad. Por lo tanto un desarrollo urbano sostenible dudosamente sería alcanzado. Se argumenta que algunos otros enfoques son necesarios para dar forma a un medio ambiente sostenible integrado, en el que se entiende que las calles son un espacio público para las personas en lugar de una plataforma para mover los vehículos solamente

  20. Strengthening public health nutrition research and training capacities in West Africa: Report of a planning workshop convened in Dakar, Senegal, 26-28 March 2009.

    Brown, Kenneth H; McLachlan, Milla; Cardosa, Placido; Tchibindat, Félicité; Baker, Shawn K

    2010-01-01

    A three-day workshop was convened in Dakar, Senegal, to provide participants from West African and international academic and research institutions, public health agencies, and donor organisations an opportunity to review current public health nutrition research and training capabilities in West Africa, assess needs for strengthening the regional institutional and workforce capacities, and discuss appropriate steps required to advance this agenda. The workshop included presentations of background papers, experiences of regional and international training programmes and small group discussions. Participants concluded that there is an urgent need to: (1) increase the throughput of public health nutrition training programmes, including undergraduate education, pre-service and in-service professional training, and higher education in public health nutrition and related research skills; and (2) enhance applied research capacity, to provide the evidence base necessary for nutrition program planning and evaluation. A Task Team was appointed to inform the regional Assembly of Health Ministers of the workshop conclusions and to develop political and financial support for a regional nutrition initiative to: (1) conduct advocacy and nutrition stewardship; (2) survey existing training programmes and assist with curriculum development; and (3) develop a plan for a regional applied research institute in Public Health Nutrition.

  1. Managing Demand and Capacity Using Multi-Sector Planning and Flexible Airspace: Human-in-the-Loop Evaluation of NextGen

    Lee, Paul U.; Smith, Nancy M.; Prevot, Thomas; Homola, Jeffrey R.

    2010-01-01

    When demand for an airspace sector exceeds capacity, the balance can be re-established by reducing the demand, increasing the capacity, or both. The Multi-Sector Planner (MSP) concept has been proposed to better manage traffic demand by modifying trajectories across multiple sectors. A complementary approach to MSP, called Flexible Airspace Management (FAM), reconfigures the airspace such that capacity can be reallocated dynamically to balance the traffic demand across multiple sectors, resulting in fewer traffic management initiatives. The two concepts have been evaluated with a series of human-in-the-loop simulations at the Airspace Operations Laboratory to examine and refine the roles of the human operators in these concepts, as well as their tools and procedural requirements. So far MSP and FAM functions have been evaluated individually but the integration of the two functions is desirable since there are significant overlaps in their goals, geographic/temporal scope of the problem space, and the implementation timeframe. Ongoing research is planned to refine the humans roles in the integrated concept.

  2. Capacity Building

    Molloy, Brian; Mallick, Shahid

    2014-01-01

    Outcomes & Recommendations: • Significant increase needed in the nuclear workforce both to replace soon-to-retire current generation and to staff large numbers of new units planned • Key message, was the importance of an integrated approach to workforce development. • IAEA and other International Organisations were asked to continue to work on Knowledge Management, Networks and E&T activities • IAEA requested to conduct Global Survey of HR needs – survey initiated but only 50% of operating countries (30% of capacity) took part, so results inconclusive

  3. Co-authorship network analysis: a powerful tool for strategic planning of research, development and capacity building programs on neglected diseases.

    Carlos Medicis Morel

    Full Text Available BACKGROUND: New approaches and tools were needed to support the strategic planning, implementation and management of a Program launched by the Brazilian Government to fund research, development and capacity building on neglected tropical diseases with strong focus on the North, Northeast and Center-West regions of the country where these diseases are prevalent. METHODOLOGY/PRINCIPAL FINDINGS: Based on demographic, epidemiological and burden of disease data, seven diseases were selected by the Ministry of Health as targets of the initiative. Publications on these diseases by Brazilian researchers were retrieved from international databases, analyzed and processed with text-mining tools in order to standardize author- and institution's names and addresses. Co-authorship networks based on these publications were assembled, visualized and analyzed with social network analysis software packages. Network visualization and analysis generated new information, allowing better design and strategic planning of the Program, enabling decision makers to characterize network components by area of work, identify institutions as well as authors playing major roles as central hubs or located at critical network cut-points and readily detect authors or institutions participating in large international scientific collaborating networks. CONCLUSIONS/SIGNIFICANCE: Traditional criteria used to monitor and evaluate research proposals or R&D Programs, such as researchers' productivity and impact factor of scientific publications, are of limited value when addressing research areas of low productivity or involving institutions from endemic regions where human resources are limited. Network analysis was found to generate new and valuable information relevant to the strategic planning, implementation and monitoring of the Program. It afforded a more proactive role of the funding agencies in relation to public health and equity goals, to scientific capacity building

  4. Co-authorship Network Analysis: A Powerful Tool for Strategic Planning of Research, Development and Capacity Building Programs on Neglected Diseases

    Morel, Carlos Medicis; Serruya, Suzanne Jacob; Penna, Gerson Oliveira; Guimarães, Reinaldo

    2009-01-01

    Background New approaches and tools were needed to support the strategic planning, implementation and management of a Program launched by the Brazilian Government to fund research, development and capacity building on neglected tropical diseases with strong focus on the North, Northeast and Center-West regions of the country where these diseases are prevalent. Methodology/Principal Findings Based on demographic, epidemiological and burden of disease data, seven diseases were selected by the Ministry of Health as targets of the initiative. Publications on these diseases by Brazilian researchers were retrieved from international databases, analyzed and processed with text-mining tools in order to standardize author- and institution's names and addresses. Co-authorship networks based on these publications were assembled, visualized and analyzed with social network analysis software packages. Network visualization and analysis generated new information, allowing better design and strategic planning of the Program, enabling decision makers to characterize network components by area of work, identify institutions as well as authors playing major roles as central hubs or located at critical network cut-points and readily detect authors or institutions participating in large international scientific collaborating networks. Conclusions/Significance Traditional criteria used to monitor and evaluate research proposals or R&D Programs, such as researchers' productivity and impact factor of scientific publications, are of limited value when addressing research areas of low productivity or involving institutions from endemic regions where human resources are limited. Network analysis was found to generate new and valuable information relevant to the strategic planning, implementation and monitoring of the Program. It afforded a more proactive role of the funding agencies in relation to public health and equity goals, to scientific capacity building objectives and a more

  5. Intentions to Participate in Counselling among Front-Line, At-Risk Irish Government Employees: An Application of the Theory of Planned Behaviour

    Hyland, Philip E.; McLaughlin, Christopher G.; Boduszek, Daniel; Prentice, Garry R.

    2012-01-01

    The study set out to examine intentions to engage in counselling among at-risk Irish government employees and the differential utility of two alternative theory of planned behaviour (TPB) models of behaviour to explain intentions to participate in counselling. Individuals (N = 259) employed in a front-line, at-risk occupation for the Irish…

  6. New plans for increasing transmission and intertie capacity : moving towards a more integrated power market in Atlantic Canada

    Roberge, F.

    2003-01-01

    This PowerPoint presentation provided a brief review of the electric power industry in Quebec after deregulation. It included an outline of non-regulated activity and regulated activities in terms of power generation, transmission, distribution and customer service. Both the transmission and distribution components of the power industry in Quebec are regulated by the Regie de l'energie. Transmission networks offer access to all wholesalers. Quebec does not have an energy spot market and electricity prices are currently very low. Hydro-Quebec TransEnergie was created in 1997 as a functionally independent open access transmission provider with high reliability standards. TransEnergie can address seams issues with neighbouring networks. The three types of services offered in terms of tariffs were also discussed in this presentation along with data regarding Hydro-Quebec assets, revenue and net income. Hydro-Quebec's relation with the Atlantic provinces were also described. Interconnection with New Brunswick totals 785 MW. No new interconnection is planned. 1 tab., 4 figs

  7. Habitual caffeine consumption and its relation to memory, attention, planning capacity and psychomotor performance across multiple age groups.

    Hameleers, P. A. H. M; Van Boxtel, M. P. J; Hogervorst, E; Riedel, W. J; Houx, P. J; Buntinx, F; Jolles, J

    2000-12-01

    The present study evaluated the association between habitual caffeine intake via coffee and tea and cognitive performance. This was done as part of a larger research programme into the determinants of cognitive ageing (the Maastricht Aging Study: MAAS). Possible withdrawal effects that may have explained in part the positive association between performance and intake in an earlier study were controlled for. In addition, all cognitive tests in this study were administered under strict laboratory conditions. A group of 1875 healthy adults, stratified for age (range 24 - 81 years), sex, and general ability, were screened for habitual intake of coffee and tea and took part in extensive cognitive testing. Multiple regression analysis with control for age, sex, socio-demographic variables, and substance use showed that habitual caffeine consumption was significantly related to better long-term memory performance and faster locomotor speed. No relationships were found between habitual caffeine consumption and short-term memory, information processing, planning, and attention as measured with the Stroop Test. Moreover, no difference in sensitivity to caffeine intake between different age groups was found, suggesting that caffeine intake did not counteract age-related cognitive decline. Several recommendations are made to improve the design of future studies in this field. Copyright 2000 John Wiley & Sons, Ltd.

  8. Plansalud: Plan sectorial concertado y descentralizado para el desarrollo de capacidades en salud, Perú 2010 - 2014 Plansalud: Decentralized and agreed sector plan for the capacity development in health, Peru 2010-2014

    Lizardo Huamán-Angulo

    2011-06-01

    Full Text Available Los recursos humanos son el eje del accionar del sector salud; sin embargo, no necesariamente son el aspecto mejor atendido, por ello el Ministerio de Salud del Perú (MINSA conjuntamente con los gobiernos regionales generó el Plan Sectorial Concertado y Descentralizado para el Desarrollo de Capacidades en Salud 2010-2014 (PLANSALUD con el propósito de fortalecer las capacidades de los Recursos Humanos en Salud (RHUS y contribuir para que la atención de salud se desarrolle con eficiencia, calidad, pertinencia, equidad e interculturalidad en el marco de la descentralización, el Aseguramiento Universal de la Salud (AUS y las políticas de la salud. Con ese objeto se han propuesto tres componentes (asistencia técnica, capacitación y articulación educación - salud que agrupan a un conjunto importante de intervenciones, las cuales son planteadas y definidas de acuerdo al contexto nacional, regional y local, contribuyendo de ese modo a la mejora de las capacidades de gobierno, de gestión por competencias y la prestación de servicios de salud. El presente artículo muestra una primera aproximación de PLANSALUD, incluyendo aspectos relacionados a su planificación, gestión, financiamiento, estructura y funcionamiento, así como las medidas de monitoreo y evaluación.Human resources are the backbone of health sector actions; however, they are not necessarily the area with the greatest attention, therefore, the Ministry of Health of Peru (MINSA together with regional governments, led the Decentralized and Agreed Sector Plan for the Capacity Development in Health 2010-2014 (PLANSALUD with the aim of strengthening the capacities of Human Resources for Health (HRH and contribute to health care efficient development, quality, relevance, equity and multiculturalism, in the context of descentralization, the Universal Health Insurance (AUS and health policies. To achieve this goal, they have proposed three components (technical assistance, joint

  9. Developing science policy capacity at the state government level: Planning a science and technology policy fellowship program for Colorado and beyond

    Druckenmiller, M. L.

    2017-12-01

    There is growing recognition of the potential to advance science policy capacity within state legislatures, where there is most often a shortage of professional backgrounds in the natural sciences, technology, engineering, and medicine. Developing such capacity at the state level should be considered a vital component of any comprehensive national scale strategy to strengthen science informed governance. Toward this goal, the Center for Science and Technology Policy Research at the University of Colorado Boulder is leading a strategic planning process for a Science and Technology Policy Fellowship Program within the Colorado state legislature and executive branch agencies. The intended program will place PhD-level scientists and engineers in one-year placements with decision-makers to provide an in-house resource for targeted policy-relevant research. Fellows will learn the intricacies of the state policymaking process, be exposed to opportunities for science to inform decisions, and develop a deeper understanding of key science and technology topics in Colorado, including water resources, wildfire management, and energy. The program's ultimate goals are to help foster a decision-making arena informed by evidence-based information, to develop new leaders adept at bridging science and policymaking realms, and to foster governance that champions the role of science in society. Parallel to efforts in Colorado, groups from nine other states are preparing similar plans, providing opportunities to share approaches across states and to set the stage for increased science and technology input to state legislative agendas nationwide. Importantly, highly successful and sustainable models exist; the American Association for the Advancement of Science (AAAS) has implemented a federally based fellowship program for over 43 years and the California Council for Science and Technology (CCST) has directed a fellowship program for their state's legislature since 2009. AAAS and CCST

  10. An investigation on forage yield capacity of kermes oak (Quercus coccifera L.) and grazing planning of Mediterranean maquis scrublands for traditional goat farming.

    Tolunay, Ahmet; Adıyaman, Elif; Akyol, Ayhan; İnce, Duygu; Türkoğlu, Türkay; Ayhan, Veysel

    2014-01-01

    This study investigated grazing capacities of maquis scrubland and preparation principles of grazing management in forest resources. Kermes oak (Quercus coccifera L.), which is widespread as a main shrub species in maquis vegetation in Turkey, and pure hair goats (Capra hircus L.) feeding on shoots and leaves of this shrub were selected for study. The study was conducted in two stages. Green leaf and shoot samples were taken from kermes oaks in the first stage and the amount of green herbage yield (g ∗ m(-1)) and dry matter yield (kg ∗ ha(-1)) that may be obtained per unit area from these samples was identified. The considered amount of dry matter consumed by pure hair goats daily and the number of goats being fed within 1 year on land of 1 ha according to different land coverage rates of kermes oaks (goat head ∗ ha ∗ yr) were calculated. In the second stage, grazing capacities of sample areas where kermes oak spread were identified and compared with the grazing plan prepared by the forestry administration for this area. Forage yield variance according to land coverage rates of maquis scrublands should be considered when determining optimum animal numbers for grazing per area for sustainable goat farming.

  11. An Investigation on Forage Yield Capacity of Kermes Oak (Quercus coccifera L. and Grazing Planning of Mediterranean Maquis Scrublands for Traditional Goat Farming

    Ahmet Tolunay

    2014-01-01

    Full Text Available This study investigated grazing capacities of maquis scrubland and preparation principles of grazing management in forest resources. Kermes oak (Quercus coccifera L., which is widespread as a main shrub species in maquis vegetation in Turkey, and pure hair goats (Capra hircus L. feeding on shoots and leaves of this shrub were selected for study. The study was conducted in two stages. Green leaf and shoot samples were taken from kermes oaks in the first stage and the amount of green herbage yield (g*m−1 and dry matter yield (kg*ha−1 that may be obtained per unit area from these samples was identified. The considered amount of dry matter consumed by pure hair goats daily and the number of goats being fed within 1 year on land of 1 ha according to different land coverage rates of kermes oaks (goat head*ha*yr were calculated. In the second stage, grazing capacities of sample areas where kermes oak spread were identified and compared with the grazing plan prepared by the forestry administration for this area. Forage yield variance according to land coverage rates of maquis scrublands should be considered when determining optimum animal numbers for grazing per area for sustainable goat farming.

  12. Remote sensing for industrial applications in the energy business: digital territorial data integration for planning of overhead power transmission lines (OHTLs)

    Terrazzino, Alfonso; Volponi, Silvia; Borgogno Mondino, Enrico

    2001-12-01

    An investigation has been carried out, concerning remote sensing techniques, in order to assess their potential application to the energy system business: the most interesting results concern a new approach, based on digital data from remote sensing, to infrastructures with a large territorial distribution: in particular OverHead Transmission Lines, for the high voltage transmission and distribution of electricity on large distances. Remote sensing could in principle be applied to all the phases of the system lifetime, from planning to design, to construction, management, monitoring and maintenance. In this article, a remote sensing based approach is presented, targeted to the line planning: optimization of OHTLs path and layout, according to different parameters (technical, environmental and industrial). Planning new OHTLs is of particular interest in emerging markets, where typically the cartography is missing or available only on low accuracy scale (1:50.000 and lower), often not updated. Multi- spectral images can be used to generate thematic maps of the region of interest for the planning (soil coverage). Digital Elevation Models (DEMs), allow the planners to easily access the morphologic information of the surface. Other auxiliary information from local laws, environmental instances, international (IEC) standards can be integrated in order to perform an accurate optimized path choice and preliminary spotting of the OHTLs. This operation is carried out by an ABB proprietary optimization algorithm: the output is a preliminary path that bests fits the optimization parameters of the line in a life cycle approach.

  13. Antiproliferative Properties Against Human Breast, Cervical and Ovarian Cancer Cell Lines, and Antioxidant Capacity of Leaf Aqueous Ethanolic Extract from Cotinus coggygria Scop.

    Gospodinova Z.

    2017-10-01

    Full Text Available Cotinus coggygria Scop. leaf aqueous ethanolic extract was examined for its in vitro antiproliferative and antioxidant activity. Antiproliferative effect was assessed on four human gynecological cancer cell lines: breast (MCF7, T47D, cervical (HeLa and ovarian (A2780 and compared to the cell growth inhibitory effect on non-cancerous breast epithelial cell line MCF10A using MTT cell proliferation assay. Radical scavenging assay with DPPH was applied to evaluate antioxidant potential of the extract. The obtained results showed that the herb inhibited cell growth of all of the tested cancer cell lines and the highest was the cytostatic effect on A2780 cells with a half maximal inhibitory concentration (IC50 value of 30.8 μg/ml. For the other cell lines the IC50 values were in the range of 55-122.7 μg/ml. Additionally, the extract exerted considerably weaker reduction in cell proliferation of the non-cancerous cell line MCF10A compared to cancer cells, which indicates for antiproliferative selectivity. C. coggygria extract showed high free radical scavenging activity with an IC50 value of 11.2 μg/ml. The obtained data provide evidence for pharmacological potential of the tested extract and future more detailed studies concerning the molecular mechanisms of the anticancer effect of the herb are needed.

  14. Evaluation of railway capacity

    Landex, Alex; Kaas, Anders H.; Schittenhelm, Bernd

    2006-01-01

    capacity consumptions. This paper describes the UIC 406 method and how it is expounded in Denmark. The paper describes the importance of choosing the right length of the line sections examined and how line sections with multiple track sections are examined. Furthermore, the possibility of using idle...

  15. Project W-314 specific test and evaluation plan for SN-633 transfer line (241-AX-B to 241-AY-02A)

    Hays, W.H.

    1998-01-01

    The purpose of this Specific Test and Evaluation Plan (STEP) is to provide a detailed written plan for the systematic testing of modifications made by the addition of the SN-633 transfer line by the W-314 Project. The STEP develops the outline for test procedures that verify the system's performance to the established Project design criteria. The STEP is a lower tier document based on the W-314 Test and Evaluation Plan (TEP). This STEP encompasses all testing activities required to demonstrate compliance to the project design criteria as it relates to the addition of transfer line SN-633. The Project Design Specifications (PDS) identify the specific testing activities required for the Project. Testing includes Validations and Verifications (e.g., Commercial Grade Item Dedication activities), Factory Acceptance Tests (FATs), installation tests and inspections, Construction Acceptance Tests (CATs), Acceptance Test Procedures (ATPs), Pre-Operational Test Procedures (POTPs), and Operational Test Procedures (OTPs). It should be noted that POTPs are not required for testing of the transfer line addition. The STEP will be utilized in conjunction with the TEP for verification and validation

  16. Admission and capacity planning for the implementation of one-stop-shop in skin cancer treatment using simulation-based optimization.

    Romero, H L; Dellaert, N P; van der Geer, S; Frunt, M; Jansen-Vullers, M H; Krekels, G A M

    2013-03-01

    Hospitals and health care institutions are facing the challenge of improving the quality of their services while reducing their costs. The current study presents the application of operations management practices in a dermatology oncology outpatient clinic specialized in skin cancer treatment. An interesting alternative considered by the clinic is the implementation of a one-stop-shop concept for the treatment of new patients diagnosed with basal cell carcinoma. This alternative proposes a significant improvement in the average waiting time that a patient spends between the diagnosis and treatment. This study is focused on the identification of factors that influence the average throughput time of patients treated in the clinic from the logistic perspective. A two-phase approach was followed to achieve the goals stated in this study. The first phase included an integrated approach for the deterministic analysis of the capacity using a demand-supply model for the hospital processes, while the second phase involved the development of a simulation model to include variability to the activities involved in the process and to evaluate different scenarios. Results showed that by managing three factors: the admission rule, resources allocation and capacity planning in the dermato-oncology unit throughput times for treatments of new patients can be decreased with more than 90 %, even with the same resource level. Finally, a pilot study with 16 patients was also conducted to evaluate the impact of implementing the one stop shop concept from a clinical perspective. Patients turned out to be satisfied with the fast diagnosis and treatment.

  17. Planning of the energy generation system expansion taking into account transmission lines; Planejamento da expansao do sistema de geracao considerando redes de transmissao

    Lucio, Joao Carlos Martins

    1990-12-31

    This work presents the proposal of a methodology which, by exploring the interaction between generation and transmission systems expansion studies, aims for an Integrated Planning of Power Systems. It intends to emphasize the Integrated Planning importance so as to improve the utilization of the available resources in the electric sector and to reduce the expansion and operational costs. The work describes a procedure to consider explicitly the network for the determination of a generation system construction schedule. It considers that the transmission lines construction costs have a significant weight so that it can modify the initial generation expansion plan with the anticipation of some investments and the postponement of others, decreasing the global expansion costs. The generation and transmission systems expansion is made in an optimal way using a Graph Search Algorithm. Finally the best Integrated Plan is obtained from a final algorithm that generates a sequence of integrated plans from combination of generation and transmission algorithms. These plans are compared from a global cost point of view until a convergence criterion has been satisfied. (author) 18 refs., 5 figs., 28 tabs.

  18. Planning of the energy generation system expansion taking into account transmission lines; Planejamento da expansao do sistema de geracao considerando redes de transmissao

    Lucio, Joao Carlos Martins

    1991-12-31

    This work presents the proposal of a methodology which, by exploring the interaction between generation and transmission systems expansion studies, aims for an Integrated Planning of Power Systems. It intends to emphasize the Integrated Planning importance so as to improve the utilization of the available resources in the electric sector and to reduce the expansion and operational costs. The work describes a procedure to consider explicitly the network for the determination of a generation system construction schedule. It considers that the transmission lines construction costs have a significant weight so that it can modify the initial generation expansion plan with the anticipation of some investments and the postponement of others, decreasing the global expansion costs. The generation and transmission systems expansion is made in an optimal way using a Graph Search Algorithm. Finally the best Integrated Plan is obtained from a final algorithm that generates a sequence of integrated plans from combination of generation and transmission algorithms. These plans are compared from a global cost point of view until a convergence criterion has been satisfied. (author) 18 refs., 5 figs., 28 tabs.

  19. Marketing Plan for the Naval Postgraduate School Master of Business Administration to the Navy Unrestricted Line Community

    Trevino, R

    2004-01-01

    .... The intent of this project is to create awareness in the Navy Unrestricted Line community about the benefits of the Defense-focused MBA and to build a brand name for the Naval Postgraduate School MBA (NPS-MBA...

  20. Activity of Saponins from Medicago species Against HeLa and MCF-7 Cell Lines and their Capacity to Potentiate Cisplatin Effect.

    Avato, Pinarosa; Migoni, Danilo; Argentieri, Mariapia; Fanizzi, Francesco P; Tava, Aldo

    2017-11-24

    Saponins from Medicago species display several biological activities, among them apoptotic effects against plant cells have been evidenced. In contrast, their cytotoxic and antitumor activity against animal cells have not been studied in great details. To explore the cytotoxic properties of saponin from Medicago species against animal cells and their effect in combination with the antitumoral drug cisplatin. Cytotoxic activity of saponin mixtures from M. arabica (tops and roots), M. arborea (tops) and M. sativa (tops, roots and seeds) and related prosapogenins from M. arborea and M. sativa (tops) against HeLa and MCF-7 cell lines is described. In addition, cytotoxicity of soyasaponin I and purified saponins (1-8) of hederagenin, medicagenic and zanhic acid is also presented. Combination experiments with cisplatin have been also conducted. Saponins from M. arabica tops and roots (mainly monodesmosides of hederagenin and bayogenin) were the most effective to reduce proliferation of HeLa and MCF-7 cell lines. Among the purified saponins, the most cytotoxic was saponin 1, 3-O-ß-D-glucopyranosyl(1→2)-α-L-arabinopyranosyl hederagenin. When saponins, derived prosapogenins and pure saponins were used in combination with cisplatin, they all, to different extent, were able to potentiate cisplatin activity against HeLa cells but not against MCF-7 cell lines. Moreover uptake of cisplatin in these cell lines was significantly reduced. Overall results showed that specific molecular types of saponins (hederagenin glycosides) have potential as anti-cancer agents or as leads for anti-cancer agents. Moreover saponins from Medicago species have evidenced interesting properties to mediate cisplatin effects in tumor cell lines. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  1. Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 27. Biogas Construction Plan in Segoroyoso Village Yogyakarta Region

    Lesmana, Surya Budi; Putra, Sri Atmaja [Muhammadiyah University of Yogyakarta, Yogyakarta (Indonesia)

    2011-10-15

    The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara (WNT) and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. To achieve the CASINDO objective seven Technical Working Groups have been established with the aim to conduct the technical activities under the various work packages and to produce the agreed deliverables. This report presents results from Technical Working Group IV on Renewable Energy project development. Its main aims were: To identify suitable non-hydro RE projects that can be developed in the province; To conduct an energy needs assessment in a selected location; To develop a business plan for a proposed solution to the identified main energy problem of the target community; To identify potential investors; To construct the project.

  2. A quick on-line state of health estimation method for Li-ion battery with incremental capacity curves processed by Gaussian filter

    Li, Yi; Abdel-Monem, Mohamed; Gopalakrishnan, Rahul; Berecibar, Maitane; Nanini-Maury, Elise; Omar, Noshin; van den Bossche, Peter; Van Mierlo, Joeri

    2018-01-01

    This paper proposes an advanced state of health (SoH) estimation method for high energy NMC lithium-ion batteries based on the incremental capacity (IC) analysis. IC curves are used due to their ability of detect and quantify battery degradation mechanism. A simple and robust smoothing method is proposed based on Gaussian filter to reduce the noise on IC curves, the signatures associated with battery ageing can therefore be accurately identified. A linear regression relationship is found between the battery capacity with the positions of features of interest (FOIs) on IC curves. Results show that the developed SoH estimation function from one single battery cell is able to evaluate the SoH of other batteries cycled under different cycling depth with less than 2.5% maximum errors, which proves the robustness of the proposed method on SoH estimation. With this technique, partial charging voltage curves can be used for SoH estimation and the testing time can be therefore largely reduced. This method shows great potential to be applied in reality, as it only requires static charging curves and can be easily implemented in battery management system (BMS).

  3. Flight route Designing and mission planning Of power line inspecting system Based On multi-sensor UAV

    Xiaowei, Xie; Zhengjun, Liu; Zhiquan, Zuo

    2014-01-01

    In order to obtain various information of power facilities such as spatial location, geometry, images data and video information in the infrared and ultraviolet band and so on, Unmanned Aerial Vehicle (UAV) power line inspecting system needs to integrate a variety of sensors for data collection. Low altitude and side-looking imaging are required for UAV flight to ensure sensors to acquire high-quality data and device security. In this paper, UAV power line inspecting system is deferent from existing ones that used in Surveying and Mapping. According to characteristics of UAV for example equipped multiple sensor, side-looking imaging, working at low altitude, complex terrain conditions and corridor type flight, this paper puts forward a UAV power line inspecting scheme which comprehensively considered of the UAV performance, sensor parameters and task requirements. The scheme is finally tested in a region of Guangdong province, and the preliminary results show that the scheme is feasible

  4. Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population

    Berquist, Brian R; Singh, Dharmendra Kumar; Fan, Jinshui

    2010-01-01

    XRCC1 operates as a scaffold protein in base excision repair, a pathway that copes with base and sugar damage in DNA. Studies using recombinant XRCC1 proteins revealed that: a C389Y substitution, responsible for the repair defects of the EM-C11 CHO cell line, caused protein instability; a V86R...... mutation abolished the interaction with POLbeta, but did not disrupt the interactions with PARP-1, LIG3alpha and PCNA; and an E98K substitution, identified in EM-C12, reduced protein integrity, marginally destabilized the POLbeta interaction, and slightly enhanced DNA binding. Two rare (P161L and Y576S...

  5. 78 FR 17714 - Notice of Availability of the HiLine District Draft Resource Management Plan and Draft...

    2013-03-22

    ... public participation activities at least 15 days in advance through public notices, media releases, and..., public land access, off-highway vehicles, lands with wilderness characteristics, wildlife habitat and..., wildfire and prescribed fire management, and social and economic conditions across the HiLine District...

  6. Six versus fewer planned cycles of first-line platinum-based chemotherapy for non-small-cell lung cancer

    Rossi, Antonio; Chiodini, Paolo; Sun, Jong-Mu

    2014-01-01

    BACKGROUND: Platinum-based chemotherapy is the standard first-line treatment for patients with advanced non-small-cell lung cancer. However, the optimum number of treatment cycles remains controversial. Therefore, we did a systematic review and meta-analysis of individual patient data to compare ...

  7. Capacity at Railway Stations

    Landex, Alex

    2011-01-01

    zone(s) the possible conflicts with other trains (also in the opposite direction) are taken into account leading to more trustworthy results. Although the UIC 406 methodology proposes that the railway network should be divided into line sections when trains turn around and when the train order...... is changed, this paper recommends that the railway lines are not always be divided. In case trains turn around on open (single track) line, the capacity consumption may be too low if a railway line is divided. The same can be the case if only few trains are overtaken at an overtaking station. For dead end...

  8. An on-line interface for integrated modeling of wildlife, climate, and society for strategic planning for the Sky Islands

    Barron J. Orr; Wolfgang Grunberg; Amanda B. Cockerham; Anne Y. Thwaits; Heather S. Severson; Noah M. D. Lerman; Rachel M. Miller; Michael Haseltine; Barbara J. Morehouse; Jonathan T. Overpeck; Stephen R. Yool; Thomas W. Swetnam; Gary L. Christopherson

    2005-01-01

    The demand for strategic planning tools that account for climate and human influences on wildfire hazard is growing. In response, the University of Arizona, through an EPA STAR Grant has undertaken interdisciplinary research to characterize the human and climate dimensions of wildfire. The resulting Fire-Climate-Society (FCS-1) prototype model developed for Sky Islands...

  9. Study of the Behavior of Some Spring Barley Lines with Two Rows Created at A.R.D.S Turda Regarding Production Capacity and Quality

    Ioana PORUMB

    2017-05-01

    Full Text Available The spring barley is a variety of a superior quality for brewing compared with the feed barley due to several reasons. Research was conducted in the field of breeding of spring barley with two rows, within ARDS Turda, during 2013-2015. The trials were comparatively developed, and included 25 variants. The biological material was represented by four  autochthonous genotypes: Turdeana, Daciana Romaniţa (A.R.D.S. Turda, and Adina (A.R.D.S. Suceava. The spring barley lines created by the S.C.D.A. Turda, meet the requirements of the beer industry in terms of protein content, starch, M.M.B. and germination energy.

  10. [Analysis on clone in vitro and tumorigenic capacity in vivo of different subsets cells from the MCF-7 human breast cancer cell line].

    Li, Zhi; Liu, Chun-ping; He, Yan-li; Tian, Yuan; Huang, Tao

    2008-07-01

    To investigate whether there are cancer stem cells in the MCF-7 human breast cancer cell line. Flow cytometry was applied to separate different subpopulation cells from MCF-7 cells, and their ability of clone in vitro and reconstruction tumor in vivo were determined. The ability of clone in vitro and reconstruction tumor in vivo were observed in some MCF-7 cells. Contrast with CD44+ CD24+ cells, the proportion of tumorigenic cancer cells in CD44+ CD24- cells is higher. Breast cancer stem cell exists in MCF-7 and it mainly locates the subpopulation of CD44+ CD24- cells, CD44+ CD24+ cell possibly is breast cancer progenitor cell.

  11. Integrated flexible capacity and inventory management under flexible capacity uncertainty

    Paç, Mehmet Fazıl

    2006-01-01

    Cataloged from PDF version of article. In a manufacturing environment with volatile demand, inventory management can be coupled with dynamic capacity adjustments for handling the fluctuations more effectively. In this study we consider the integrated management of inventory and flexible capacity management under seasonal stochastic demand and uncertain labor supply. The capacity planning problem is investigated from the workforce planning perspective. We consider a manufactu...

  12. Second Line of Defense, Port of Buenos Aires and Exolgan Container Terminal Operational Testing and Evaluation Plan, Buenos Aires, Argentina

    Roberts, Bryan W.

    2012-08-23

    The Office of the Second Line of Defense (SLD) Megaports project team for Argentina will conduct operational testing and evaluation (OT&E) at Exolgan Container Terminal at the Port of Dock Sud from July 16-20, 2012; and at the Port of Buenos Aires from September 3-7, 2012. SLD is installing radiation detection equipment to screen export, import, and transshipment containers at these locations. The purpose of OT&E is to validate and baseline an operable system that meets the SLD mission and to ensure the system continues to perform as expected in an operational environment with Argentina Customs effectively adjudicating alarms.

  13. Simulation of 3D-treatment plans in head and neck tumors aided by matching of digitally reconstructed radiographs (DRR) and on-line distortion corrected simulator images

    Lohr, Frank; Schramm, Oliver; Schraube, Peter; Sroka-Perez, Gabriele; Seeber, Steffen; Schlepple, Gerd; Schlegel, Wolfgang; Wannenmacher, Michael

    1997-01-01

    Background and purpose: Simulation of 3D-treatment plans for head and neck malignancy is difficult due to complex anatomy. Therefore, CT-simulation and stereotactic techniques are becoming more common in the treatment preparation, overcoming the need for simulation. However, if simulation is still performed, it is an important step in the treatment preparation/execution chain, since simulation errors, if not detected immediately, can compromise the success of treatment. A recently developed PC-based system for on-line image matching and comparison of digitally reconstructed radiographs (DRR) and distortion corrected simulator monitor images that enables instant correction of field placement errors during the simulation process was evaluated. The range of field placement errors with noncomputer aided simulation is reported. Materials and methods: For 14 patients either a primary 3D-treatment plan or a 3D-boost plan after initial treatment with opposing laterals for head and neck malignancy with a coplanar or non-coplanar two- or three-field technique was simulated. After determining the robustness of the matching process and the accuracy of field placement error detection with phantom measurements, DRRs were generated from the treatment planning CT-dataset of each patient and were interactively matched with on-line simulator images that had undergone correction for geometrical distortion, using a landmark algorithm. Translational field placement errors in all three planes as well as in-plane rotational errors were studied and were corrected immediately. Results: The interactive matching process is very robust with a tolerance of <2 mm when suitable anatomical landmarks are chosen. The accuracy for detection of translational errors in phantom measurements was <1 mm and for in-plane rotational errors the accuracy had a maximum of only 1.5 deg.. For patient simulation, the mean absolute distance of the planned versus simulated isocenter was 6.4 ± 3.9 mm. The in

  14. Environment Canada's new on-line reporting system for environmental emergency plans under CEPA, Sections 199 and 200

    Rudin-Brown, P.

    2003-01-01

    One of the objectives of Canada's Environmental Emergencies program is to reduce the frequency, severity and consequences of spill events by promoting preventative measures and emergency preparedness. The program also offers advice on response methods and advancing science and technology. This paper from a poster session announces that the E2 program is expected to be administered online by late 2003. The compiled database is expected to serve as a useful statistical reference for the public, decision makers, and first responders. Users will be able to access information regarding controlled substances. In particular, sections 199 and 200 of the Environmental Emergency regulations in the Canadian Environmental Protection Act (CEPA) require that any person in Canada who manages a listed substance in large quantities provide Environment Canada with information on the quantity of the substance, the facility location, and prepare a contingency plan

  15. A interdependência entre sistemas de controle de produção e critérios de alocação de capacidades The relationship between production planning and control systems and methods of capacity allocation

    Fernando Bernardi de Souza

    2002-08-01

    Full Text Available Há uma aparente carência de pesquisas sobre os inter-relacionamentos entre critérios de alocação de capacidades de recursos de manufatura e os métodos de controle de produção. Estudos sobre alocação de capacidades se baseiam geralmente em sistemas simplificados de empurrar a produção, desconsiderando sistemas mais atuais de gestão de produção. Por outro lado, pesquisas sobre a aplicabilidade de sistemas de gestão da produção não consideram apropriada a maneira como as capacidades produtivas dos recursos estão alocadas ao longo da linha. Analisar as interdependências entre esses dois grandes ramos de pesquisa é o objetivo deste artigo.There is a lack of researches on the relationship between methods of capacity allocation of manufacturing resources and production planning and control systems. Studies about capacity allocation are based on simplified push production systems not considering more current production management systems. By other side, studies about efficiency of production management systems don't consider the effect of different criteria of capacity allocation of manufacturing resources at the results. The purpose of this paper is to investigate how the different policies of capacity allocation and different production planning and control systems interrelate between each other.

  16. Implant Rehabilitation Planning Protocol for the Edentulous Patient According to Denture Space, Lip Support, and Smile Line.

    Lago, Laura; Rilo, Benito; Fernández-Formoso, Noelia; DaSilva, Luis

    2017-08-01

    Rehabilitation with implants is a challenge. Having previous evaluation criteria is key to establishing the best treatment for the patient. In addition to clinical and radiological aspects, the prosthetic parameters must be taken into account in the initial workup, since they allow discrimination between fixed and removable rehabilitation. We present a study protocol that analyzes three basic prosthetic aspects. First, denture space defines the need to replace teeth, tissue, or both. Second, lip support focuses on whether or not to include a flange. Third, the smile line warns of potential risks in esthetic rehabilitation. Combining these parameters allows us to make a decision as to the most suitable type of prosthesis. The proposed protocol is useful for assessing the prosthetic parameters that influence decision making as to the best-suited type of restoration. From this point of view, we think it is appropriate for the initial approach to the patient. In any case, other considerations of study may amend the proposal. © 2016 by the American College of Prosthodontists.

  17. Evaluating the strategic capacity of collaborative spatial planning initiatives by the performance of its process, output and outcomes : The case of the southern Randstad Holland

    Harteveld, E.; Waterhout, B.; Broekhans, B.; Zonneveld, W.A.M.

    2015-01-01

    Spatial planning practices are constantly evolving to be more effective in a dynamic context. In the face of the latest developments, the practice of collaborative spatial planning through the formation of regional collaborations has emerged as the contemporary solution. The practice of working with

  18. Capacity Measurement with the UIC 406 Capacity Method

    Landex, Alex; Schittenhelm, Bernd; Kaas, Anders H.

    2008-01-01

    This article describes the fast and effective UIC 406 method for calculating capacity consumption on railway lines. It is possible to expound the UIC 406 method in different ways which can lead to different capacity consumptions. Therefore, this article describes how the methodology is expounded...

  19. Carrying capacity and tourism planning. case study at Praia Brava- Itajai, in face to the settlement of Canto da Brava Resort

    Doris Van de Meene Ruschmann

    2008-05-01

    Full Text Available Sustainable tourism presumes cultural authenticity, social inclusion, conservation of natural resources and service quality. Those are major issues standing for economical viability in the long run. This article analyzes carrying capacity in Praia Brava, Itajai/SC, evaluating environmental comfort for dwellers as well as for users of the beach building future scenarios as Canto da Brava resort is settled. Tourism carrying capacity is tied to methods of identification and evaluation of environmental indicators. In this case, Cifuentes Method was chosen because it integrates physical, biotical and infra structural factors, through assessment of physical, real and effective carrying capacity. Quantitative results have been considered analyzing impacts and tolerable limits of change taking into account users perception.

  20. The UIC 406 capacity method used on single track sections

    Landex, Alex; Kaas, Anders H.; Jacobsen, Erik M.

    2007-01-01

    This paper describes the relatively new UIC 406 capacity method which is an easy and effective way of calculating capacity consumption on railway lines. However, it is possible to expound the method in different ways which can lead to different capacity consumptions. This paper describes the UIC...... 406 method for single track lines and how it is expounded in Denmark. Many capacity analyses using the UIC 406 capacity method for double track lines have been carried out and presented internationally but only few capacity analyses using the UIC 406 capacity method on single track lines have been...... presented. Therefore, the differences between capacity analysis for double track lines and single track lines are discussed in the beginning of this paper. Many of the principles of the UIC 406 capacity analyses on double track lines can be used on single track lines – at least when more than one train...

  1. Available transmission capacity assessment

    Škokljev Ivan

    2012-01-01

    Full Text Available Effective power system operation requires the analysis of vast amounts of information. Power market activities expose power transmission networks to high-level power transactions that threaten normal, secure operation of the power system. When there are service requests for a specific sink/source pair in a transmission system, the transmission system operator (TSO must allocate the available transfer capacity (ATC. It is common that ATC has a single numerical value. Additionally, the ATC must be calculated for the base case configuration of the system, while generation dispatch and topology remain unchanged during the calculation. Posting ATC on the internet should benefit prospective users by aiding them in formulating their requests. However, a single numerical value of ATC offers little for prospect for analysis, planning, what-if combinations, etc. A symbolic approach to the power flow problem (DC power flow and ATC offers a numerical computation at the very end, whilst the calculation beforehand is performed by using symbols for the general topology of the electrical network. Qualitative analysis of the ATC using only qualitative values, such as increase, decrease or no change, offers some new insights into ATC evaluation, multiple transactions evaluation, value of counter-flows and their impact etc. Symbolic analysis in this paper is performed after the execution of the linear, symbolic DC power flow. As control variables, the mathematical model comprises linear security constraints, ATC, PTDFs and transactions. The aim is to perform an ATC sensitivity study on a five nodes/seven lines transmission network, used for zonal market activities tests. A relatively complicated environment with twenty possible bilateral transactions is observed.

  2. Tumor-treating fields elicit a conditional vulnerability to ionizing radiation via the downregulation of BRCA1 signaling and reduced DNA double-strand break repair capacity in non-small cell lung cancer cell lines.

    Karanam, Narasimha Kumar; Srinivasan, Kalayarasan; Ding, Lianghao; Sishc, Brock; Saha, Debabrata; Story, Michael D

    2017-03-30

    The use of tumor-treating fields (TTFields) has revolutionized the treatment of recurrent and newly diagnosed glioblastoma (GBM). TTFields are low-intensity, intermediate frequency, alternating electric fields that are applied to tumor regions and cells using non-invasive arrays. The predominant mechanism by which TTFields are thought to kill tumor cells is the disruption of mitosis. Using five non-small cell lung cancer (NSCLC) cell lines we found that there is a variable response in cell proliferation and cell killing between these NSCLC cell lines that was independent of p53 status. TTFields treatment increased the G2/M population, with a concomitant reduction in S-phase cells followed by the appearance of a sub-G1 population indicative of apoptosis. Temporal changes in gene expression during TTFields exposure was evaluated to identify molecular signaling changes underlying the differential TTFields response. The most differentially expressed genes were associated with the cell cycle and cell proliferation pathways. However, the expression of genes found within the BRCA1 DNA-damage response were significantly downregulated (Pionizing radiation resulted in increased chromatid aberrations and a reduced capacity to repair DNA DSBs, which were likely responsible for at least a portion of the enhanced cell killing seen with the combination. These findings suggest that TTFields induce a state of 'BRCAness' leading to a conditional susceptibility resulting in enhanced sensitivity to ionizing radiation and provides a strong rationale for the use of TTFields as a combined modality therapy with radiation or other DNA-damaging agents.

  3. The predictive capacity of the theory of reasoned action and the theory of planned behavior in exercise research: an integrated literature review.

    Blue, C L

    1995-04-01

    Although the association between habitual exercise and health benefits has been well documented, physical activity levels in the United States are lower than is necessary to reach the nation's health potential. Beliefs that people hold can be a motivating factor in engaging in exercise. A critical review of the literature was conducted to assess the efficacy of using the Theory of Reasoned Action and the Theory of Planned Behavior with respect to exercise. Evidence for the predictive utility of the theories was found. The Theory of Planned Behavior is a more promising framework for the study of exercise because it includes beliefs about control of factors that would facilitate or inhibit carrying out exercise. Strategies for use of the theories in planning exercise programs are provided and suggestions for future research discussed.

  4. Demand Response Potential for California SubLAPs and Local Capacity Planning Areas: An Addendum to the 2025 California Demand Response Potential Study – Phase 2

    Alstone, Peter [Humboldt State Univ., Arcata, CA (United States). Schatz Energy Research Center; Potter, Jennifer [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Piette, Mary Ann [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Schwartz, Peter [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Berger, Michael A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dunn, Laurel N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Smith, Sarah J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sohn, Michael D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Aghajanzadeh, Arian [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Stensson, Sofia [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Szinai, Julia [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-04-01

    The 2025 California Demand Response Potential Study Phase 2 Report1 was released on March 1, 2017, and described a range of pathways for Demand Response (DR) to support a clean, stable, and cost-effective electric grid for California. One of the Report’s key findings was that while there appears to be very low future value for untargeted DR Shed aimed at system-wide peak load conditions, there could be significant value for locally focused Shed resources. Although the dynamics of renewable capacity expansion have reduced the pressure to build new thermal generation in general, there are still transmission-constrained areas of the state where load growth needs to be managed with the addition of new local capacity, which could include DERs and/or DR. This Addendum to the Phase 2 Report presents a breakdown of the expected future “Local Shed” DR potential at a finer geographic resolution than what is available in the original report, with results summarized by SubLAP and Local Capacity Area (LCA).

  5. SU-F-T-138: Commissioning and Evaluating Dose Computation Models for a Dedicated Proton Line Scanning Beam Nozzle in Eclipse Treatment Planning System

    Tsai, P [Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Tao-yuan, Taiwan (China); Chang Gung University, Taoyuan, Taiwan (China); Huang, H; Cai, S; Chen, H; Wu, S; Wu, T; Lee, S; Yeh, C; Wu, T [Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Tao-yuan, Taiwan (China); Lee, C [Chang Gung University, Taoyuan, Taiwan (China)

    2016-06-15

    Purpose: In this study, we present an effective method to derive low dose envelope of the proton in-air spot fluence at beam positions other than the isocenter to reduce amount of measurements required for planning commission. Also, we demonstrate commissioning and validation results of this method to the Eclipse treatment planning system (version 13.0.29) for a Sumitomo dedicated proton line scanning beam nozzle. Methods: The in-air spot profiles at five beam-axis positions (±200, ±100 and 0 mm) were obtained in trigger mode using a MP3 Water tank (PTW-Freiburg) and a pinpoint ionization chamber (model 31014, PTW-Freiburg). Low dose envelope (below 1% of the center dose) of the spot profile at isocenter was obtained by repeated point measurements to minimize dosimetry uncertainty. The double Gaussian (DG) model was used to fit and obtain optimal σ1, σ2 and their corresponding weightings through our in-house MATLAB (Mathworks) program. σ1, σ2 were assumed to expand linearly along the beam axis from a virtual source position calculated by back projecting fitted sigmas from the single Gaussian (SG) model. Absolute doses in water were validated using an Advanced Markus chamber at the depth of 2cm with Pristine Peak (BP) R90d ranging from 5–32 cm for 10×10 cm2 scanned fields. The field size factors were verified with square fields from 2 to 20 cm at 2cm and before BP depth. Results: The absolute dose outputs were found to be within ±3%. For field size factor, the agreement between calculated and measurement were within ±2% at 2cm and ±3% before BP, except for the field size below 2×2 cm2. Conclusion: The double Gaussian model was found to be sufficient for characterizing the Sumitomo dedicated proton line scanning nozzle. With our effective double Gaussian fitting method, we are able to save significant proton beam time with acceptable output accuracy.

  6. Assessing the gap between the acute trauma workload and the capacity of a single rural health district in South Africa. What are the implications for systems planning?

    Clarke, D L; Aldous, C; Thomson, S R

    2014-06-01

    This study focuses on a single rural health district in South Africa, and attempts to establish the burden of disease and to review the capacity of the district hospitals to deal with this load. Ethical approval to undertake this study was obtained from both the University of Kwa-Zulu Natal and the Department of Health. The audit was performed over a 6-month period in the four district hospitals of rural Sisonke District. There were four components to this audit. 1. Information on the hospital incidence of acute trauma in Sisonke was also sourced from the epidemiology unit of the Department of Health in Pietermaritzburg 2. Each of the district hospitals was visited and the medical manager was interviewed. The medical manager was asked to complete the World Health Organization's Tool for Situational Analysis to Assess Emergency and Essential Surgical Care. (SAT). 3. The operative registers were reviewed to determine the number of index cases for trauma. This information was used to determine the unmet need of acute trauma in the district. 4. Each hospital was classified according to the Trauma Society of South Africa (TSSA) guidelines for levels of trauma care. The annual incidence of trauma in the Sisonke District is estimated to be 1,590 per 100,000 population. Although there appeared to be adequate infrastructure in the district hospitals, the SAT revealed significant deficits in terms of capacity of staff to adequately treat and triage acute trauma patients. There is a significant unmet need for trauma care in Sisonke. The four district hospitals can best be classified as Level IV centers of trauma care. There is a significant burden of trauma in the Sisonke District, yet the capacity to deal with this burden is inadequate. Although the physical infrastructure is adequate, the deficits relate to human resources. The strategic choices are between enhancing the district hospitals' capacity to deal with acute trauma, or deciding to bypass them completely and

  7. Exerting Capacity.

    Leger, J Michael; Phillips, Carolyn A

    2017-05-01

    Patient safety has been at the forefront of nursing research since the release of the Institute of Medicine's report estimating the number of preventable adverse events in hospital settings; yet no research to date has incorporated the perspectives of bedside nurses using classical grounded theory (CGT) methodology. This CGT study explored the perceptions of bedside registered nurses regarding patient safety in adult acute care hospitals. Data analysis used three techniques unique to CGT-the constant comparative method, coding, and memoing-to explore the values, realities, and beliefs of bedside nurses about patient safety. The analysis resulted in a substantive theory, Exerting Capacity, which explained how bedside nurses balance the demands of keeping their patients safe. Exerting Capacity has implications for health care organization leaders, nursing leaders, and bedside nurses; it also has indications for future research into the concept of patient safety.

  8. On-line packed magnetic in-tube solid phase microextraction of acidic drugs such as naproxen and indomethacin by using Fe3O4@SiO2@layered double hydroxide nanoparticles with high anion exchange capacity.

    Shamsayei, Maryam; Yamini, Yadollah; Asiabi, Hamid; Safari, Meysam

    2018-02-22

    The authors describe a 3-component nanoparticle system composed of a silica-coated magnetite (Fe 3 O 4 ) core and a layered double (Cu-Cr) hydroxide nanoplatelet shell. The sorbent has a high anion exchange capacity for extraction anionic species. A simple online system, referred to as "on-line packed magnetic-in-tube solid phase microextraction" was designed. The nanoparticles were placed in a stainless steel cartridge via dry packing. The cartridge was then applied to the preconcentration acidic drugs including naproxen and indomethacin from urine and plasma. Extraction and desorption times, pH values of the sample solution and flow rates of sample solution and eluent were optimized. Analytes were then quantified by HPLC with UV detection. Under optimal conditions, the limits of detection range from 70 to 800 ng L -1 , with linear responses from 0.1-500 μg L -1 (water samples), 0.6-500 μg L -1 (spiked urine), and 0.9-500 μg L -1 (spiked plasma). The inter- and intra-assay precisions (RSDs, for n = 5) are in the range of 2.2-5.4%, 2.8-4.9%, and 2.0-5.2% at concentration levels of 5, 25 and 50 μg L -1 , respectively. The method was applied to the analysis of the drugs in spiked human urine and plasma, and good results were achieved. Graphical abstract Fe 3 O 4 @SiO 2 @CuCr-LDH magnetic nanoparticles were synthesized and packed in to a stainless steel column. The column was applied to solid phase microextraction of acidic drugs from biological samples.

  9. Capacitated Dynamic Lot Sizing with Capacity Acquisition

    Li, Hongyan; Meissner, Joern

    One of the fundamental problems in operations management is to determine the optimal investment in capacity. Capacity investment consumes resources and the decision is often irreversible. Moreover, the available capacity level affects the action space for production and inventory planning decisions...

  10. Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 24. Regional Energy Efficiency Planning 2011 [for Yogyakarta

    Prahara, Pamungkas Jutta; Hariadi, T.K. [Universitas Muhammadiyah PUSPER-UMY, Yogyakarta (Indonesia)

    2012-06-15

    The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. Increasing energy demand and decreasing energy supply has to be faced by strategic measures. Daerah Istimewa Yogyakarta (DIY) faces the same problem with more burdens since DIY depends on energy supply from other region. One strategic measure is to reduce energy consumption across sectors. There are, in total, 805.468 electricity consumers in Yogyakarta in the household, social and industrial sector. Through direct measures electricity consumption can be reduced and financial resources can be saved. One of the measures is energy conservation campaign to all sectors in the region which expected to reduce the energy spent, for example to switch off electronic devices totally instead of to put them in standby mode. Survey in the region indicated there are various use of electronic devices in household dominated by refrigeration, television, and AC's. In industries and social, AC and motors are dominating the sector. By applying inverter technology and refrigerant retrofitting to air conditioner can reduce significantly the energy consumption. Changing from old refrigerator with new energy saver refrigerator would also reduce energy consumption. Strategic energy policy and tools has to be identified to push the community to apply the recommended measure. Energy labeling, tax reduction program and energy price increase would make the energy conservation program more feasible and create an environment where inventing in energy efficiency is more attractive. Furthermore a financial resource policy has to be prepared for community education through promotion

  11. Decision project related to the energy multi-year 2018/2023 planning (PPE). Evolution of capacities of production of power generating renewable energies: the headlong rush

    Perves, Jean-Pierre

    2016-01-01

    After having recalled that the French government, in its energy multi-year planning for 2018-2023, decided to develop wind and photovoltaic energies at a higher rate, despite their intermittency and the need for back-up nuclear and hydroelectric power plants (which do not emit carbon), and outlined that the power market is now in the torment, in France and in Europe, the author notices that such a development of renewable energies is a matter of concern in Europe, and indicates the objectives defined by the French government for onshore and offshore wind energy and for solar energy. Then, he proposes a critical analysis of the low level scenario of this development, a scenario which the author assesses as not very realistic. A table indicates the status and objectives for all the different renewable energies. The author discusses these values, notices that it is similar to a programme defined by the ADEME. He analyses the 2018/2023 low scenario (production, share, production efficiency, minimum and maximum power) by comparing it with the situation in 2015. He outlines important seasonal variations for wind and solar energy: their production level in winter requires a massive use of other sources. He briefly discusses the perspectives for 2030, and then addresses the development cost in terms of required investments. He discusses the impact of the scenario on greenhouse gas emissions. The appendix provides the official text of the decision project

  12. Uranium Mill Tailings Remedial Action Project Environmental Line Management Audit Action Plan. Final report. Audit, October 26, 1992--November 6, 1992

    1993-07-01

    This Action Plan contains responses, planned actions, and estimated costs for addressing the findings discovered in the Environmental Management Audit conducted for the U.S. Department of Energy (DOE) Uranium Mill Tailings Remedial Action Project (UMTRA), October 26 through November 6, 1992. This document should be read in conjunction with the Audit Report to ensure the findings addressed in this document are fully understood. The scope of the UMTRA Environmental Management Audit was comprehensive and encompassed all areas of environmental management except environmental programs pertaining to the National Environmental Policy Act (NEPA) compliance. The Audit Report listed 18 findings: 11 were identified as compliance findings, and the remaining 7 were best management practice findings. Root cause analysis was performed on all the findings. The results of the analysis as well as planned corrective actions are summarized in Section 5.0. All planned actions were prioritized using the Tiger Team Assessment Corrective Action Plan system. Based on assigned priorities, all planned actions were costed by fiscal year. This Action Plan contains a description of the organizational and management structures to be used to implement the Action Plan, a brief discussion of root cause analysis and funding, followed by the responses and planned actions for each finding. A member of the UMTRA Project Office (PO) has been assigned responsibility for tracking the progress on each of the findings. The UMTRA PO staff wrote and/or approved all of the corrective actions recorded in this Action Plan

  13. Capacity Markets and Market Stability

    Stauffer, Hoff

    2006-01-01

    The good news is that market stability can be achieved through a combination of longer-term contracts, auctions for far enough in the future to permit new entry, a capacity management system, and a demand curve. The bad news is that if and when stable capacity markets are designed, the markets may seem to be relatively close to where we started - with integrated resource planning. Market ideologues will find this anathema. (author)

  14. A high voltage power line: the route with the least environmental and health impact. Public consultation on the plan to rebuild the 400 kV power line between Lille and Arras

    Carlier, Jean-Louis; Chardonnet, Claude

    2017-01-01

    The upgrade to double-circuit of the 400-kV power line between Avelin and Gavrelle (Northern France) was first set in motion to improve security and to adapt the network to renewable energy sources or energy transition. Since 2011, it has been the object of an unprecedented consultation process, in terms of duration as well as magnitude. From 2012 to 2015, after much discussion, the contracting authority, Reseau Transport d'Electricite (RTE), determined the line with the least consequential environmental and health effects and presented it to the 2016 spring public inquiry. Information and communication requirements were adapted at each stage of the project, to take local concerns into account. Health concerns about the magnetic fields and noise generated by the electric lines were expressed from the very beginning of the consultation and were therefore treated with special care, through knowledge-sharing, debate and specific studies. A health committee, comprising volunteers from various backgrounds, was entrusted with informing the general public and providing suggestions to RTE and the health authorities, through in-depth discussions about health issues. The committee also asked RTE to conduct studies and measure electromagnetic fields to support an informed decision. As a result, the contracting authority defined the route of the electric line based primarily on the distance between houses and the line. The committee also obtained further commitments from RTE to minimize the magnetic fields emitted by the line with a new type of pylon and to monitor the effects on the people living along the line over time. During the course of this consultation process, shared knowledge together with a continuous dialogue on local health concerns aided the search for the route with the least consequential environmental and health impact. (authors)

  15. Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 25. Renewable Energy Action Plan of West Nusa Tenggara Province 2010-2025

    NONE

    2011-08-15

    The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. This report is expected to become a reference for government and private sectors in the development of renewable energy in West Nusa Tenggara Province, not only the development of renewable energy for electricity generation, but also for other needs such as fuel for industry and cooking fuel for households. The Renewable Energy Action Plan of West Nusa Tenggara Province is a follow-up of the enactment of Presidential Regulation No. 5 Year 2006 concerning National Energy Policy, which the Central Government has set a target utilization of renewable energy by 2025 by 17%. Furthermore, this document contains data and information regarding current utilization of renewable energy, renewable energy potential and development opportunities, target of renewable energy development and action plans necessary to achieve the targets.

  16. Model of clinker capacity expansion

    Stylianides, T

    1998-10-01

    Full Text Available This paper describes a model which has been applied in practice to determine an optimal plan for clinker capacity expansion. The problem was formulated as an integer linear program aiming to determine the optimal number, size and location of kilns...

  17. Survey of transmission line corridors. [Data on delays in transmission line construction

    1979-01-05

    The intent of this study is to determine the extent of delays experienced in planning and constructing transmission lines in the continental United States. The reasons for the delays are identified for each line studied and their effect on the total electrical system is sought. Data was collected for 136 different lines either recently built or currently under study. Statistics were developed for each line in several categories and comparisons of lines delayed were made by company, area served and generation capacity. From the study presented here it was found that: right-of-way acquisition procedures including condemnation and easement negotiation practices delay more projects than local, state and federal regulatory requirements combined; load growth reductions particularly in the east have reduced the impact of regulatory delays; the south, southeast and southwestern areas of the country experience fewer delays in constructing transmission lines than the more populated states, and the cost for corridor delays was responded to for only 17 of the 142 projects surveyed. By far the most costly delay is the expense of condemning land for transmission right-of-way.

  18. Ebeye 2023: Comprehensive Capacity Development Master Plan

    2012-07-01

    Administration, Population and Demography , Information Systems, and Geospatial Science. The cost per credit hour at USP is estimated to be between...prosperity for a city. This statistic, coupled with the other determinants such as inflation , provide an assessment of a population’s ability to grow and...developing the fishing industry is the fishing rights are currently sold to Japan , which is a major stumbling block for commercial fishing. These

  19. Urgent Aeromedical Evacuation Network Capacity Planning

    2013-03-01

    What if AMC had one strategically positioned AC for the Urgent / Priority AE mission and the redistribution needs they encounter? This idea stems ...KtMI~rAFB _~...,_ Po~AFB ;------------~ Service Tirr~e Estimates I CO\\" CLl "SIO\\" • C-378 performs bestfrom a cost perspective • Contracted

  20. The use of an on-line computer system for radiotherapy planning. Part of a coordinated programme on computer applications in clinical dosimetry

    Tatcher, M.

    1977-07-01

    The aim of radiotherapy is to deliver a predetermined dose to the volume of a tumor in order to destroy it without at the same time harming healthy tissues nearby. The calculation of the dose distribution in a patient's body in order to determine the optimum arrangement of beam geometry is the central problem in treatment planning. For this task computers are increasingly being used as dose calculations by hand are time-consuming and exclude the application of modern treatment strategies. The objectives of this work were to set up a minimal departmental computer system for cobalt-60 radiotherapy treatment planning. Computer programmes were written for the following radiotherapy applications: Co-60 output charts (monthly charts of dose rate for determination of treatment time); interactive programme for calculating and optimizing isodose distributions to be used for treatment planning; calculation of irregular dose distributions of beams with arbitrary shape; gynecological radiotherapy, using internal Cs-137 and Ra-226 sources; linear isodose charts for 8 MV X-rays by interpolation from measured data. All programmes are written in BASIC. However, as BASIC does not link directly with the graphics devices, all programmes will be converted to FORTRAN, based on CUNNINGHAM's work. Although in principle the treatment planning programme in BASIC is satisfactory, it is not fast enough to replace manual calculations. Routine interactive computerized treatment planning will be possible once the FORTRAN programmes are operational. For all other routine purposes the BASIC radiotherapy programmes are suitable

  1. Network development plan 1995

    Anon.

    1995-11-01

    Network plan 1995 concerns several strategic problems, among others environmental policy of power transmission lines. Possibilities of restructuring aerial cable network are described. The state of the existing systems and plans for new network systems are presented. (EG)

  2. Patient admission planning using Approximate Dynamic Programming

    Hulshof, P.J.H.; Mes, Martijn R.K.; Boucherie, Richardus J.; Hans, Elias W.

    2016-01-01

    Tactical planning in hospitals involves elective patient admission planning and the allocation of hospital resource capacities. We propose a method to develop a tactical resource allocation and patient admission plan that takes stochastic elements into consideration, thereby providing robust plans.

  3. Management plan for electrical insulation, transformers and bulbs high pressure sodium retired from electrical distribution lines of the Unidad Estrategica de Negocios Servicio al Cliente Electricidad of the Instituto Costarricense de Electricidad

    Badilla Sanabria, Daniela; Chaves Morales, Angelica; Rodriguez Mendez, Susan

    2012-01-01

    The Unidad Estrategica de Negocios Servicio al Cliente Electricidad of Instituto Costarricense de Electricidad has completed a management plan for electrical insulation, transformers and sodium vapor bulbs high pressure, that are retired from electrical distribution lines. The three residues have been characterized and identified in its physical composition, chemical and hazardous properties, generating selection, analysis and proposals for alternative of recovery, treatment or final disposal, viable from an environmental, technical and economic view. A series of recommendations and procedures have been performed using tabs and instructions for the purpose of unifying management practices appropriate in the Area de Sostenibilidad Ambiental of the ICE. (author) [es

  4. Using Evaluation for CBNRM Capacity Development (Southeast Asia)

    Using Evaluation for CBNRM Capacity Development (Southeast Asia) ... for evaluating both the process and outcome of capacity development efforts in CBNRM. ... Cluster Case Studies Planning Workshop, Beijing, September 21-23, 2006; ...

  5. Strengthening our approaches to building capacity

    CCAA

    and capacity building mandate. A number of ... of CCAA capacity building: participatory action research (PAR) mentoring ... project, to ensure its application in planning, monitoring ... community volunteers who use climate information in emergency response ... has expertise in monitoring and evaluation, and the Department.

  6. Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST).

    Nigrovic, Peter A; Beukelman, Timothy; Tomlinson, George; Feldman, Brian M; Schanberg, Laura E; Kimura, Yukiko

    2018-03-01

    Systemic juvenile idiopathic arthritis is a rare febrile arthritis of childhood characterized by a potentially severe course, including prolonged glucocorticoid exposure, growth failure, destructive arthritis, and life-threatening macrophage activation syndrome. Early cytokine-blocking biologic therapy may improve long-term outcomes, although some systemic juvenile idiopathic arthritis patients respond well to non-biologic treatment, leaving optimal management undefined. Consequently, treatment of new-onset systemic juvenile idiopathic arthritis by expert clinicians varies widely. To describe a pragmatic, observational comparative effectiveness study that takes advantage of diversity in the management of a rare disease: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST), comparing non-biologic and biologic consensus treatment plans for new-onset systemic juvenile idiopathic arthritis within the 60-center Childhood Arthritis and Rheumatology Research Alliance Registry (CARRA). FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST) is a multicenter, prospective, non-randomized study that compares four Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment plans for new-onset systemic juvenile idiopathic arthritis: (1) glucocorticoids alone, (2) methotrexate, (3) interleukin-1 blockade, and (4) interleukin-6 blockade. Patients consenting to participation in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry are started on one of four Consensus Treatment Plans at the discretion of the treating physician. The outcome of primary interest is clinically inactive disease off glucocorticoids at 9 months, comparing non-biologic (Consensus Treatment Plans 1 + 2) versus biologic (Consensus Treatment Plans 3 + 4) strategies. Bayesian analytic methods will be employed to evaluate response rates, using propensity scoring to balance treatment groups for potential

  7. 1992 Annual Capacity Report

    1993-05-01

    The Standard Contract for Disposal of Spent Nuclear Fuel and/or High-Level Radioactive Waste (10 CFR Part 961) requires the Department of Energy (DOE) to issue an Annual Capacity Report (ACR) for planning purposes. This report is the fifth in the series published by DOE. In May 1993, DOE published the 1992 Acceptance Priority Ranking (APR) that established the order in which DOE will allocate projected acceptance capacity. As required by the Standard Contract, the acceptance priority ranking is based on the date the spent nuclear fuel (SNF) was permanently discharged, with the owners of the oldest SNF, on an industry-wide basis, given the highest priority. The 1992 ACR applies the projected waste acceptance rates in Table 2.1 to the 1992 APR, resulting in individual allocations for the owners and generators of the SNF. These allocations are listed in detail in the Appendix, and summarized in Table 3.1. The projected waste acceptance rates for SNF presented in Table 2.1 are nominal and assume a site for a Monitored Retrievable Storage (MRS) facility will be obtained; the facility will initiate operations in 1998; and the statutory linkages between the MRS facility and the repository set forth in the Nuclear Waste Policy Act of 1982, as amended (NWPA), will be modified. During the first ten years following projected commencement of Civilian Radioactive Waste Management System (CRWMS) operation, the total quantity of SNF that could be accepted is projected to be 8,200 metric tons of uranium (MTU). This is consistent with the storage capacity licensing conditions imposed on an MRS facility by the NWPA. The annual acceptance rates provide an approximation of the system throughput and are subject to change as the program progresses

  8. Computer Based ex-ante Evaluation of the Planned Railway Line between Copenhagen and Ringsted by use of a Decision Support System named COSIMA-DSS

    Salling, Kim Bang; Landex, Alex

    2006-01-01

    This paper presents an appraisal study concerning the extension of the main railway line between Copenhagen and Ringsted by use of a software system named COSIMA-DSS. The modelling system is based upon a multi-methodological approach combining a cost-benefit analysis together with a multi......-criteria analysis. One of the key impacts in cost-benefit analyses is the time benefit which depends on the timetabling. The paper describes some of the challenges related to the calculation of the time benefits and how the time benefits can be implemented in the decision support system. At the end of the paper...

  9. Perencanaan dan analisis kehandalan sistem komunikasi radio microwave tampak pandang pada pita frekuensi 12750-13250 MHz [Planning and analysis of the reliability of line of sight microwave radio communication system on 12750-13250 MHz band

    Ahmad Hasyim

    2016-12-01

    Full Text Available Propagasi gelombang radio dapat diartikan sebagai proses perambatan gelombang radio dari pemancar ke penerima. Gelombang ini akan merambat melalui udara bebas menuju antena penerima dan mengalami redaman di sepanjang lintansannya,  redaman perangkat dan saluran transmisi, sehingga ketika sampai di antena penerima, energi sinyal sudah sangat lemah. Line of sight    (LOS merupakan salah satu jenis propagasi di mana diantara stasiun pengirim dan stasiun penerima  tidak terdapat penghalang. Kendala geografis dan kelengkungan bumi menyebabkan adanya keterbatasan untuk transmisi line of sight, namun masalah ini secara umum dapat dikurangi melalui perencanaan, perhitungan dan penggunaan teknologi tambahan. Dalam perencanaan sistem komunikasi radio, kinerja LOS perlu direncanakan cadangan daya akibat fluktuasi sinyal serta analisis kehandalannya. Sistem radio gelombang mikro digital antar titik yang menggunakan  frekuensi 13 GHz dengan modulasi 16 QAM, bit rate 140 MBps,dan  noise figure 0,7 dB memerlukan daya pancar -4,488 dBm, fading margin sebesar 85,51 dB dan kehandalannya sebesar 99,9999999%.*****Radio wave propagation can be defined as the process of propagation of radio waves from the transmitter to the receiver. These waves will propagate through free air towards the receiver antena with experienced curbs along the tracks, so when it arrive at the receiver antena, the signal energy is very slow. Line of sight (LOS is one kind of propagation where no obstacles found between the transmitter and the receiver station. Geographical constraints and the curvature of the earth bring limitations to the line of sight transmission, but this problem can generally be reduced through planning, calculation and use of additional technologies. In a radio communication system planning, LOS performance needs to be planned caused by signal fluctuations and reliability. Digital microwave point to point radio systems using 13 GHz of spectrum, 16 QAM of

  10. Development of a magnetic resonance sensor for on-line monitoring of 99Tc and 23Na in tank waste cleanup processes: Final report and implementation plan

    Dieckman, S. L.; Jendrzejczyk, J. A.; Raptis, A. C.

    2000-01-01

    In response to US Department of Energy (DOE) requirements for advanced cross-cutting technologies, Argonne National Laboratory is developing an on-line sensor system for the real-time monitoring of 99 Tc and 23 Na in various locations throughout radioactive-waste processing facilities. Based on nuclear magnetic resonance spectroscopy, the highly automated sensor system can provide near-real-time response with minimal sampling. The technology, in the form of a flow-through nuclear-magnetic-resonance-based on-line process sensing and control system, can rapidly monitor 99 Tc speciation and concentration (from 0.1 molar to 10 micro molar) in the feedstocks and eluents of radioactive-waste treatment processes. The system is nonintrusive, capable of withstanding harsh plant environments, and reasonably immune to contaminants. Furthermore, the system is capable of operating over large variations in pH, conductivity, and salinity. This document describes design parameters, results from sensitivity studies, and initial results obtained from oxidation-reduction studies that were conducted on technetium standards and waste specimens obtained from DOE's Hanford site. A cursory investigation of the system's capabilities to monitor 23 Na at high concentrations are also reported, as are descriptions of site requirements, implementation recommendations, and testing techniques

  11. Planning your first wind power project. A primer for utilities: Everything you need to know to bring your first wind power plant on-line

    Conover, K.; Davis, E.

    1994-12-01

    This primer has been prepared to help utility personnel become familiar with some or the details relative to wind power technology and project development. It is written as a series of relatively independent chapters to address specific topics or phases of wind power evaluation and development as they might occur within a utility. The topics include: wind prospecting and the first pass analysis, resource validation, project feasibility, resource planning and evaluation, resource acquisition, project development, equipment selection, project design and construction, and plant operation and maintenance

  12. Guidance for implementing an environmental, safety, and health-assurance program. Volume 15. A model plan for line organization environmental, safety, and health-assurance programs

    Ellingson, A.C.; Trauth, C.A. Jr.

    1982-01-01

    This is 1 of 15 documents designed to illustrate how an Environmental, Safety and Health (ES and H) Assurance Program may be implemented. The generic definition of ES and H Assurance Programs is given in a companion document entitled An Environmental, Safety and Health Assurance Program Standard. This particular document presents a model operational-level ES and H Assurance Program that may be used as a guide by an operational-level organization in developing its own plan. The model presented here reflects the guidance given in the total series of 15 documents.

  13. Electric and magnetic field reduction by alternative transmission line options

    Stewart, J.R. (Power Technologies, Inc., Schenectady, NY (United States)); Dale, S.J. (Oak Ridge National Lab., TN (United States)); Klein, K.W. (Energetics, Inc., Columbia, MD (United States))

    1991-01-01

    Ground level electric, and more recently magnetic, fields from overhead power transmission lines are increasingly important considerations in right of way specification, with states setting or planning to set edge of right of way limits. Research has been conducted in high phase order power transmission wherein six of twelve phases are used to transmit power in less physical space and with reduced electrical environmental effects than conventional designs. The first magnetic field testing, as reported in this paper, has verified predictive methods for determination of magnetic fields from high phase order lines. Based on these analytical methods, field profiles have been determined for lines of different phase order of comparable power capacity. Potential advantages of high phase order as a means of field mitigation are discussed. 10 refs., 12 figs., 3 tabs.

  14. Bike Map Lines

    Town of Chapel Hill, North Carolina — Chapel Hill Bike Map Lines from KMZ file.This data came from the wiki comment board for the public, not an “official map” showing the Town of Chapel Hill's plans or...

  15. Improving Technology And Setting-Up A Production Line For High Quality Zinc Oxide (99.5%) With A Capacity Of 150 Ton/Year By Reduction-Oxidation Process

    Pham Minh Tuan; Tran The Dinh; Tran Ngoc Vuong; Tuong Duy Nhan; Tran Trung Son; Le Huu Thiep; Nguyen Trung Dung; Le Thi Hong; Luong Manh Hung; Bui Huy Cuong

    2014-01-01

    Zinc oxide is used not only for the rubber industry, but also in many other industries such as pigments, ceramics, cosmetics etc. On the basis of references on international scientific researches and practical activities for the production of zinc oxide in our country, we have carried out additional research and testing to establish a zinc oxide production line for preparation of high quality (99.5%) product by treating the industrial zinc containing waste to obtain required composition materials [Zn] >50%; [Pb] < 0.3%; [Cl]/[PbO] < 0.2 for reduction-oxidation processes using reverberatory furnace. (author)

  16. On-line task scheduling and trajectory planning techniques for reconnaissance missions with multiple unmanned aerial vehicles supervised by a single human operator

    Ortiz Rubiano, Andres Eduardo

    The problem of a single human operator monitoring multiple UAVs in reconnaissance missions is addressed in this work. In such missions, the operator inspects and classifies targets as they appear on video feeds from the various UAVs. In parallel, the aircraft autonomously execute a flight plan and transmit real-time video of an unknown terrain. The main contribution of this work is the development of a system that autonomously schedules the display of video feeds such that the human operator is able to inspect each target in real time (i.e., no video data is recorded and queued for later inspection). The construction of this non-overlapping schedule is made possible by commanding changes to the flight plan of the UAVs. These changes are constructed such that the impact on the mission time is minimized. The development of this system is addressed in the context of both fixed and arbitrary target inspection times. Under the assumption that the inspection time is constant, a Linear Program (LP) formulation is used to optimally solve the display scheduling problem in the time domain. The LP solution is implemented in the space domain via velocity and trajectory modifications to the flight plan of the UAVs. An online algorithm is proposed to resolve scheduling conflicts between multiple video feeds as targets are discovered by the UAVs. Properties of this algorithm are studied to develop conflict resolution strategies that ensure correctness regardless of the target placement. The effect of such strategies on the mission time is evaluated via numerical simulations. In the context of arbitrary inspection time, the human operator indicates the end of target inspection in real time. A set of maneuvers is devised that enable the operator to inspect each target uninterruptedly and indefinitely. In addition, a cuing mechanism is proposed to increase the situational awareness of the operator and potentially reduce the inspection times. The benefits of operator cuing on mission

  17. 基于旅游生产线的景区容量计算模型构建及与传统模式的比较分析%The construction of tourism space carrying capacity calculation model based on production line and the competitive with traditional models

    鄢慧丽

    2011-01-01

    Recently, in several articles, scholar Huang Yangshan analyzed the method of calculating the carry capacity of scenic area, and pointed out the limitation of traditional method based on the turnover. Then he deduced an improved model. But in his studies there is no comparison analysis to the difference of the optimal capacity value of the models in different conditions, and his improved model still has some limitation. Therefore, this paper first presents a new tourism scenic capacity calculation model based on production line, then analyses the balance of the attraction time and the attraction capacity of the scenic depot, which is the important fact influencing the volume of the carry capacity. And then, we compared our new model with the traditional ones in different condition. The results show that the new model based on tourism production line is suitable for wider scope, and is more reasonable.%近期,黄羊山在多篇文章中对风景区旅游空间容量的方法进行了探讨,且指出了传统周转率法的局限性,并说明了模型错误的原因.但其分析偏于定性,且没有指出不同条件下,这些模型求得的容量值的情况.本文首先提出了一种新的基于旅游生产线的景区容量计算模型,接着分析了景点时间和景点容量均衡与否对景区容量计算的影响,并对新的景区容量计算模型与传统景区容量计算模型进行了量化比较研究.结果表明基于旅游生产线的景区容量计算模型适用范围更广、更具有一般性.

  18. Northern entanglement : Arctic gas pipeline plans caught in web of competing interests, but dire supply-demand forecasts indicate line will be built

    Stonehouse, D.

    2005-01-01

    This article discussed land access and regulatory issues surrounding decisions to stop field work of the Mackenzie Valley pipeline in the spring of 2005. Although current supply and demand balances in natural gas markets argue that the pipeline will be beneficial, Imperial Oil and its partners have halted activities such as geotechnical data-gathering programs and preparatory work on contracting construction. The project's future depends on the successful resolution of First Nations land claims, governmental disputes and various activist groups protesting the pipeline's construction. Imperial Oil has suggested that the pipeline presents a significant opportunity for the people of the North to reduce their reliance on government and will create jobs and business opportunities for Aboriginal people. In the aftermath of work stoppage, Alberta's former Energy Minister stated that imports of Liquefied Natural Gas (LNG) and Alaska gas from the proposed Alaska Highway Pipeline Project may arrive on the market in advance of the Mackenzie Valley project, which would affect the project's financial future. It was noted that access and benefits agreements with First Nations stakeholders have yet to be reached. Lawsuits involving the Deh Cho First Nations were examined. It was also suggested that Imperial Oil has not included information on the Alberta portion of the project in its environmental impact assessment. It was concluded that if the Mackenzie Delta line isn't in service by 2010, North American consumers can expect to spend an extra $190 billion on gas from 2011 to 2020. 3 figs

  19. 32 CFR 644.7 - Acquisition lines.

    2010-07-01

    ... HANDBOOK Project Planning Civil Works § 644.7 Acquisition lines. (a) Tentative acquisition lines. As..., in accordance with sound real estate practices. Accordingly, fringe tracts will not be acquired until...

  20. Autoshuttle: Concept and Commercial Example Line

    Andreas Steingrover

    2003-05-01

    Full Text Available The transport system AUTOSHUTTLE integrates roadand track guided traffic using and combining the specific advantagesof each of these means of transportation. Conventionalroad vehicles are transported including their passengersand freight in individual cabins. The operational concept ofA UTOSHUTTLE provides operation of the cabins without intermediatestops at almost constant travelling speed. During thejourney convoys with low aerodynamic drag are formed in orderto lower the energy consumption and increase traffic capacity.Approaching a station only those cabins that have reachedtheir destination leave the convoy on a passive switch and decelerateon a brake track, while other cabins close the gap in theconvoy and travel on at the usual cruising speed. This paper describesthe planning and economical aspects of a proposedcommercia/line along the motorway A3 in Germany betweenthe cities of Duisburg and Cologne as a typical example formany other applications.

  1. Apoptosis Induction by Polygonum minus is related to antioxidant capacity, alterations in expression of apoptotic-related genes, and S-phase cell cycle arrest in HepG2 cell line.

    Mohd Ghazali, Mohd Alfazari; Al-Naqeb, Ghanya; Krishnan Selvarajan, Kesavanarayanan; Hazizul Hasan, Mizaton; Adam, Aishah

    2014-01-01

    Polygonum minus (Polygonaceae) is a medicinal herb distributed throughout eastern Asia. The present study investigated antiproliferative effect of P. minus and its possible mechanisms. Four extracts (petroleum ether, methanol, ethyl acetate, and water) were prepared by cold maceration. Extracts were subjected to phytochemical screening, antioxidant, and antiproliferative assays; the most bioactive was fractionated using vacuum liquid chromatography into seven fractions (F1-F7). Antioxidant activity was measured via total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric reducing antioxidant power (FRAP) assays. Antiproliferative activity was evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Most active fraction was tested for apoptosis induction and cell cycle arrest in HepG2 cells using flow cytometry and confocal microscopy. Apoptotic-related gene expression was studied by RT-PCR. Ethyl acetate extract was bioactive in initial assays. Its fraction, F7, exhibited highest antioxidant capacity (TPC; 113.16 ± 6.2 mg GAE/g extract, DPPH; EC50: 30.5 ± 3.2 μg/mL, FRAP; 1169 ± 20.3 μmol Fe (II)/mg extract) and selective antiproliferative effect (IC50: 25.75 ± 1.5 μg/mL). F7 induced apoptosis in concentration- and time-dependent manner and caused cell cycle arrest at S-phase. Upregulation of proapoptotic genes (Bax, p53, and caspase-3) and downregulation of antiapoptotic gene, Bcl-2, were observed. In conclusion, F7 was antiproliferative to HepG2 cells by inducing apoptosis, cell cycle arrest, and via antioxidative effects.

  2. Improving technology and setting-up a production line for high quality zinc oxide (99.5%) with a capacity of 150 ton/year by evaporation-oxidation process

    Phan Dinh Thinh; Pham Minh Tuan; Luong Manh Hung; Tran Ngoc Vuong

    2015-01-01

    This report presents the technology improvement and a production line to produce high quality zinc oxide of purity upper than 99.5% ZnO by evaporation-oxidation method. Secondary zinc metal recovered from galvanizing industrial will undergo a pre-treatment to meet all requirements of standardized feed material for evaporation-oxidation process. Zinc metal is melted at a temperature of about 650"oC, some impurities and metallic oxides are separated preliminary, then zinc metal is converted into liquid in evaporation pot. Here the temperature is maintained around 1050"oC, zinc liquid is evaporated, zinc vapor is oxidized by air in the oxidation chamber naturally by oxygen in the air and then zinc vapor is converted to zinc oxide. Zinc oxide is passed through a product classification systems and then go to a product collection of filtering bag design. The whole process of melting, evaporation, oxidation, particles classification and product collection is a continuous process. The efficiency of the transformation of zinc metal into zinc oxide can reach the value of 1.1 to 1.2. ZnO product quality is higher than 99.5%. (author)

  3. Capacity Building in the IAEA’s Technical Cooperation Programme

    Acuna, Oscar

    2014-01-01

    Good Practice on Capacity Building - The UNDP/UNDG Approach: Key Steps: 1. Engage stakeholders on capacity development: - in broader national, sectoral, thematic or programme-based development plans, strategies and priorities; - consult all relevant actors and secure the support; - ensure appropriate team composition. 2. Assess capacity assets and needs: - point of entry; - core issues; - the nature of capacity. 3. Formulate a Capacity Development Response: - a capacity development response; - indicators of progress for a capacity development response; - budgeting a capacity development response. 4. Implement the Capacity Development Response: - capacity development strategies in programming; - monitoring from inputs to outputs; - managing implementation through national systems and process; - continuous link with national development. 5. Evaluate Capacity Development focusing on the Outputs Impacts

  4. MOPSO-based multi-objective TSO planning considering uncertainties

    Wang, Qi; Zhang, Chunyu; Ding, Yi

    2014-01-01

    factors, i.e. load growth, generation capacity and line faults, and aims to enhance the transmission system via the multi-objective TSO planning (MOTP) approach. The proposed MOTP approach optimizes three objectives simultaneously, namely the probabilistic available transfer capability (PATC), investment...... cost and power outage cost. A two-phase MOPSO algorithm is employed to solve this optimization problem, which can accelerate the convergence and guarantee the diversity ofPareto-optimal front set as well. The feasibility and effectiveness of both the proposed multi-objective planning approach...

  5. Behind Lines

    Dayer, Carolina

    2017-01-01

    translations. The plan drawing, understood as the Vitruvian footprint—ichnographia—of the building, is a mark metonymically connected with the reality of architecture. Through a process of multiple methodological transfers and translations, the plan drawing operates as a continuum in flux that subsequently...

  6. High Line

    Kiib, Hans

    2015-01-01

    At just over 10 meters above street level, the High Line extends three kilometers through three districts of Southwestern Manhattan in New York. It consists of simple steel construction, and previously served as an elevated rail line connection between Penn Station on 34th Street and the many....... The High Line project has been carried out as part of an open conversion strategy. The result is a remarkable urban architectural project, which works as a catalyst for the urban development of Western Manhattan. The greater project includes the restoration and reuse of many old industrial buildings...

  7. Proceedings from a Workshop on Ecological Carrying Capacity of Salmonids in the Columbia River Basin : Measure 7.1A of the Northwest Power Planning Council`s 1994 Fish and Wildlife Program : Report 3 of 4, Final Report.

    Johnson, Gary E.; Neitzel, D.A.; Mavros, William V.

    1996-05-01

    This report contains the proceedings of a workshop held during 1995 in Portland, Oregon. The objective of the workshop was to assemble a group of experts that could help us define carrying capacity for Columbia River Basin salmonids. The workshop was one activity designed to answer the questions asked in Measure 7.1A of the Council`s Fish and Wildlife Program. Based, in part, on the information we learned during the workshop we concluded that the approach inherent in 7.1A will not increase understanding of ecology, carrying capacity, or limiting factors that influence salmon under current conditions. Measure 7.1A requires a definition of carrying capacity and a list of determinants (limiting factors) of capacity. The implication or inference then follows that by asking what we know and do not know about the determinants will lead to research that increases our understanding of what is limiting salmon survival. It is then assumed that research results will point to management actions that can remove or repair the limiting factors. Most ecologists and fisheries scientists that have studied carrying capacity clearly conclude that this approach is an oversimplification of complex ecological processes. To pursue the capacity parameter, that is, a single number or set of numbers that quantify how many salmon the basin or any part of the basin can support, is meaningless by itself and will not provide useful information.

  8. Transmission and capacity pricing and constraints

    Fusco, M.

    1999-01-01

    A series of overhead viewgraphs accompanied this presentation which discussed the following issues regarding the North American electric power industry: (1) capacity pricing transmission constraints, (2) nature of transmission constraints, (3) consequences of transmission constraints, and (4) prices as market evidence. Some solutions suggested for pricing constraints included the development of contingent contracts, back-up power in supply regions, and new line capacity construction. 8 tabs., 20 figs

  9. Internet plan and planning

    Kahriman Emina

    2008-01-01

    Full Text Available Paper discuss specific features of internet plan as well as planning as management process in general in the contemporary environment. No need to stress out that marketing plan and marketing planning is core activity in approaching to market. At the same time, there are a lot specific c request in preparing marketing plan comparing to business planning due to marketing plan is an essential part. The importance of internet plan and planning rely on specific features of the internet network but as a part of general corporate as well as marketing strategy.

  10. Competition under capacitated dynamic lot-sizing with capacity acquisition

    Li, Hongyan; Meissner, Joern

    2011-01-01

    Lot-sizing and capacity planning are important supply chain decisions, and competition and cooperation affect the performance of these decisions. In this paper, we look into the dynamic lot-sizing and resource competition problem of an industry consisting of multiple firms. A capacity competition...... production setup, along with inventory carrying costs. The individual production lots of each firm are limited by a constant capacity restriction, which is purchased up front for the planning horizon. The capacity can be purchased from a spot market, and the capacity acquisition cost fluctuates...

  11. Total iron binding capacity

    ... page: //medlineplus.gov/ency/article/003489.htm Total iron binding capacity To use the sharing features on this page, please enable JavaScript. Total iron binding capacity (TIBC) is a blood test to ...

  12. Budget Impact Analysis of Afatinib for First-Line Treatment of Patients with Metastatic Non-Small Cell Lung Cancer with Epidermal Growth Factor Receptor Exon 19 Deletions or Exon 21 Substitution Mutations in a U.S. Health Plan.

    Graham, Jonathan; Earnshaw, Stephanie; Burslem, Kate; Lim, Jonathan

    2018-06-01

    Afatinib is 1 of 3 tyrosine kinase inhibitors approved in the United States for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions (del19) or exon 21 (L858R) substitution mutations. In clinical trials, afatinib has demonstrated improvement in progression-free survival versus standard chemotherapy and gefitinib. To analyze the impact of increases in afatinib treatment share on the cost and health outcomes in a commercial health plan in the United States. A decision model was developed to evaluate the budget impact of increases in afatinib share for the first-line treatment of patients with metastatic NSCLC with EGFR del19 or L858R substitution mutations over a 5-year time horizon. The model compared the total annual costs for a health plan with 1 million covered lives in a scenario in which afatinib share increased 5 percentage points annually to one in which all treatment shares remained constant over time. The number of patients eligible for treatment was estimated using published incidence data. Therapies included in the model were afatinib, erlotinib, gefitinib, and the chemotherapy doublet, pemetrexed in combination with cisplatin. The mean time spent by patients in progression-free and progressive disease states was based on survival data from clinical trials and a network meta-analysis. Therapy-related costs included monthly drug acquisition and administration costs and costs of managing adverse reactions. Disease management costs were also assessed in the model. Scenario analyses were performed to assess alternative scenarios of afatinib treatment share. Additionally, a one-way sensitivity analysis was performed to test the robustness of the model, given parameter uncertainty. Using the base-case parameter assumptions and a 5-percentage-point annual increase in afatinib treatment share, we estimated the total budget increases in years 1 through 5

  13. Air capacity for Sydney

    Forsyth, Peter

    2013-01-01

    Like most large cities, Sydney has an airport problem. Demand is increasing faster than supply, and additional capacity will be needed if costly rationing, and delays, are to be avoided. However, compared to many cities, the problems facing Sydney are modest. At the moment, demand is only just exceeding capacity. There is a good chance that the available capacity will be rationed efficiently. Options for expanding capacity are being evaluated well. There may be problems in the future- poor op...

  14. Responsibility and Capacities

    Ryberg, Jesper

    2014-01-01

    That responsible moral agency presupposes certain mental capacities, constitutes a widely accepted view among theorists. Moreover, it is often assumed that degrees in the development of the relevant capacities co-vary with degrees of responsibility. In this article it is argued that, the move from...... the view that responsibility requires certain mental capacities to the position that degrees of responsibility co-vary with degrees of the development of the mental capacities, is premature....

  15. World lines.

    Waser Jürgen; Fuchs Raphael; Ribicic Hrvoje; Schindler Benjamin; Blöschl Günther; Gröller Eduard

    2010-01-01

    In this paper we present World Lines as a novel interactive visualization that provides complete control over multiple heterogeneous simulation runs. In many application areas decisions can only be made by exploring alternative scenarios. The goal of the suggested approach is to support users in this decision making process. In this setting the data domain is extended to a set of alternative worlds where only one outcome will actually happen. World Lines integrate simulation visualization and...

  16. Hydropower planning coordinated with wind power in areas with congestion problems for trading on the spot and the regulating market

    Matevosyan, Julija; Olsson, Magnus; Soeder, Lennart

    2009-01-01

    In this paper a day-ahead planning algorithm for a multi-reservoir hydropower system coordinated with wind power is developed. Coordination applies to real situations, where wind power and hydropower are owned by different utilities, sharing the same transmission lines, though hydropower has priority for transmission capacity. Coordination is thus necessary to minimize wind energy curtailments during congestion situations. The planning algorithm accounts for the uncertainty of wind power forecasts and power market price uncertainty. Planning for the spot market and the regulating market is considered in the algorithm. The planning algorithm is applied to a case study and the results are summarized in the paper. (author)

  17. PAYMENT CAPACITY SENSITIVITY FACTORS

    Daniel BRÎNDESCU – OLARIU

    2014-11-01

    The results of the study facilitate the determination and classification of the main sensitivity factors for the payment capacity at sample level, the establishment of general benchmarks for the payment capacity (as no such benchmarks currently exist in the Romanian literature and the identification of the mechanisms through which the variation of different factors impacts the payment capacity.

  18. GTRgaz: investment plan

    Anon.

    2007-01-01

    GTRgaz company published on June 2007 its indicative development plan for the 10 years to come. This document serves as a communication vector between GTRgaz and the actors of the market and presents the projects of development of the gas transportation network as defined on the basis of the evolution of French and European markets, and on the knowledge of capacity needs directly or indirectly expressed by the suppliers community. This article summarizes the different points of this plan: reduction of the number of balancing points, development of interconnection capacities, development of output capacities, network free interplay improvement beyond 2013. (J.S.)

  19. Capacity Building in Land Management

    Enemark, Stig; Ahene, Rexford

    2003-01-01

    There is a significant need for capacity building in the interdisciplinary area of land management especially in developing countries and countries in transition, to deal with the complex issues of building efficient land information systems and sustainable institutional infrastructures. Capacity...... building in land management is not only a question of establishing a sufficient technological level or sufficient economic resources. It is mainly a question of understanding the interdisciplinary and cross-sectoral nature of land administration systems, and understanding the need for human resource...... and professionals for implementing the new land policy. The curriculum combines the diploma and the bachelor level and it combines the key areas of land surveying, land management and physical planning....

  20. Capacity building for HIA

    Gabriel Gulis PhD

    2007-09-01

    Full Text Available

    Background: To integrate health impact assessment (HIA into existing decision-making processes requires not only methods and procedures but also well-trained experts, aware policy makers and appropriate institutions. Capacity building is the assistance which is provided to entities, which have a need to develop a certain skill or competence, or for general upgrading of performance ability. If a new technique is planned to be introduced there is a need for capacity building with no respect to levels (local, regional, national, international or sectors (health, environment, finance, social care, education, etc.. As such, HIA is a new technique for most of the new Member States and accession countries of the European Union.

    Methods: To equip individuals with the understanding and skills needed to launch a HIA or be aware of the availability of this methodology and to access information, knowledge and training, we focused on the organization of workshops in participating countries. The workshops served also as pilot events to test a “curriculum” for HIA; a set of basic topics and presentations had been developed to be tested during workshops. In spite of classical in-class workshops we aimed to organize e-learning events as a way to over come the “busyness” problem of decision makers.

    Results: Throughout March – October 2006 we organized and ran 7 workshops in Denmark, Turkey, Lithuania, Poland, Bulgaria, Slovak Republic and Hungary. Participants came from the public health sector (141, non-public health decision makers (113 and public health students (100. A concise curriculum was developed and tested during these workshops. Participants developed a basic understanding of HIA, skills to develop and use their own screening tools as well as scoping.Within the workshop in Denmark we tested an online, real-time Internet based training method; participants highly welcomed this

  1. Capacity Expansion Modeling for Storage Technologies

    Hale, Elaine; Stoll, Brady; Mai, Trieu

    2017-04-03

    The Resource Planning Model (RPM) is a capacity expansion model designed for regional power systems and high levels of renewable generation. Recent extensions capture value-stacking for storage technologies, including batteries and concentrating solar power with storage. After estimating per-unit capacity value and curtailment reduction potential, RPM co-optimizes investment decisions and reduced-form dispatch, accounting for planning reserves; energy value, including arbitrage and curtailment reduction; and three types of operating reserves. Multiple technology cost scenarios are analyzed to determine level of deployment in the Western Interconnection under various conditions.

  2. Ten-Year Network Development Plan - 2015 edition, executive summary

    2016-01-01

    Complying with the European and French laws, each year, RTE prepares and publicizes a Ten-Year Network Development Plan (NDP) to meet the expectations of its stakeholders and customers. The NDP lists the network development projects that RTE plans to complete and commission over a 3-year period and presents the main power transmission infrastructure work envisaged for the next Ten-years. Beyond, it outlines the possible network adaptation needs for a variety of energy transition scenarios. Over the next 10 years, the network investments will make it possible to: - Meet the goals of the Regional Climate Air Energy Plans, - Create 4 GW of extra offshore wind generation integration capacity and 10 GW of additional interconnection capacity, 2/3 more than the current capacity, - Enable the development of economically and demographically dynamic areas, with safe and high-standard electricity supply. In the coming decade, RTE plans: - 1,200 km of new underground and sub-sea DC links, along with their associated converter stations; - 600 km of existing equipment upgrades or new overhead 400 kV AC circuits substituting existing power lines. - and, at the same time, nearly 900 km of underground lines and just over 400 km of overhead 225 kV AC lines should be built. 400 projects are listed in this NDP: - 21% of the operations are on overhead lines (for 3/4 new lines or upgrade and for 1/4 dismantling of existing assets) - 27% concern new underground lines; - 52% on substation adaptations (about 20 new RTE substations and 100 new customer substations connected). Globally, nearly 80% of the network is developed underground or sub-sea. This edition of the Network Development plan is further enriched. In particular, it explains more thoroughly the link between the integration of renewable energy and the entailed development of the transmission network. It also provides a focus on smart grids. This edition relies on mid and long term scenarios describing the evolution of the

  3. Capacity of Intelligent Underlay and Overlay Network

    Ling, Yim; Elling, Jan; Nielsen, Thomas Toftegaard

    1996-01-01

    traffic. The formulas of the model have been implemented with the use of MatLab. To verify the model, measurement methods have been developed to collect the teletraffic information in a real-live GSM network. The measured data indicates that the teletraffic model describes the capacity with high accuracy...... and therefore can be used to dimension the network. The model shows that the increase of capacity for a GSM network with 34 frequencies is about 30%. Further capacity enhancement can be achieved by intelligent frequency planning method which is currently being developed...

  4. Isoeffect lines using TDF and CRE concepts

    Supe, S.J.; Sasane, J.B.; Supe, D.S.

    1980-01-01

    Isoeffect lines based on Ellis' Nominal Standard Dose concept, Orton's Time Dose and Fractionation Factor (TDF) concept, and Kirk et al's Cumulative Radiation Effect (CRE) concept give differing results of treatment planning. Experience with isoeffect lines based on the above concepts in planning in case of radiotherapy for carcinoma of bladder and carcinoma of uterine cervix is narrated. (M.G.B.)

  5. A Framework to Support the Fusion of Operation and Planning

    Chen, Yousu; Etingov, Pavel V.; Fitzhenry, Erin B.; Sharma, Poorva; Nguyen, Tony B.; Makarov, Yuri V.; Rice, Mark J.; Allwardt, Craig H.; Widergren, Steven E.

    2015-12-31

    The management of the nation’s power system has progressed to the point where the boundary lines between operations and planning are becoming blurred. The dynamic behavior of smart grid technologies brings pressures of incorporating the predictive capability from planning to enhance operations. These needs are requiring a smoother, better integrated interplay between the functional roles of planning and operations. This paper presents a framework to support the fusion of operation and planning. A case study of predicting the intra-hour deficiency in generation capability and ramping capacity and presenting the outputs to operators was conducted. The study shows the benefits of the fusion and the effectiveness of the framework. All the function blocks used in the study were built upon GridOPTICS Software System (GOSS), a software system middleware platform that facilitates deployment of new applications for the future power grid.

  6. Silver linings.

    Bultas, Margaret W; Pohlman, Shawn

    2014-01-01

    The purpose of this interpretive phenomenological study was to gain a better understanding of the experiences of 11 mothers of preschool children with autism spectrum disorder (ASD). Mothers were interviewed three times over a 6 week period. Interviews were analyzed using interpretive methods. This manuscript highlights one particular theme-a positive perspective mothers described as the "silver lining." This "silver lining" represents optimism despite the adversities associated with parenting a child with ASD. A deeper understanding of this side of mothering children with ASD may help health care providers improve rapport, communication, and result in more authentic family centered care. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Electrochemical impedance studies of capacity fading of ...

    2017-06-09

    Jun 9, 2017 ... low cost, and has a theoretical capacity of 978 mAh g. −1. , which is higher than that of ..... Projections of (a) 100 and (b) 110 crystal planes of wurtzite ZnO showing their non-polar nature. Dashed horizontal lines identify .... ernment of India, for financial support through the award of a Ramanna Fellowship to ...

  8. Capacity building in emerging space nations: Experiences, challenges and benefits

    Jason, Susan; da Silva Curiel, Alex; Liddle, Doug; Chizea, Francis; Leloglu, Ugur Murat; Helvaci, Mustafa; Bekhti, Mohammed; Benachir, Djouad; Boland, Lee; Gomes, Luis; Sweeting, Martin

    2010-09-01

    This paper focuses on ways in which space is being used to build capacity in science and technology in order to: Offer increasing support for national and global solutions to current and emerging problems including: how to improve food security; resource management; understanding the impacts of climate change and how to deal with them; improving disaster mitigation, management and response. Support sustainable economic development. We present some of the experiences, lessons learned and benefits gained in capacity building projects undertaken by Surrey Satellite Technology Ltd. and our partners from developing and mature space nations. We focus on the Turkish, Algerian and Nigerian know-how and technology transfer programmes which form part of the first Disaster Monitoring Constellation (DMC) in orbit. From the lessons learned on Surrey's know-how and technology transfer partnership programmes, it is clear that space technology needs to be implemented responsibly as part of a long-term capacity building plan to be a sustainable one. It needs to be supported with appropriate policy and legal frameworks, institutional development, including community participation, human resources development and strengthening of managerial systems. In taking this on board, DMC has resulted in a strong international partnership combining national objectives, humanitarian aid and commerce. The benefits include: Ownership of space-based and supporting ground assets with low capital expenditure that is in line with national budgets of developing nations. Ownership of data and control over data acquisition. More for the money via collaborative consortium. Space related capacity building in organisations and nations with the goal of sustainable development. Opportunities for international collaboration, including disaster management and relief.

  9. The French capacity mechanism

    2014-01-01

    The French capacity mechanism has been design to ensure security of supply in the context of the energy transition. This energy transition challenges the electricity market design with several features: peak load growth, the development of renewables, demand response,... To ensure security of supply in this context, a capacity mechanism is being implemented in France. It is a market wide capacity obligation on electricity suppliers, based on market principles. Suppliers are responsible for forecasting their obligation, which corresponds to their contribution to winter peak load, and must procure enough capacity certificates to meet their obligations. Capacity certificates are granted to capacities through a certification process, which assesses their contribution to security of supply on the basis of availability commitments. This certification process is technology neutral and performance based, associated with controls and penalties in case of non compliance. Demand Side is fully integrated in the market, either through the reduction of suppliers' capacity obligation or direct participation after certification. In addition to the expected benefits in terms of security of supply, the French capacity market will foster the development of demand response. The participation of foreign capacities will require adaptations which are scheduled in a road-map, and could pave the way for further European integration of energy policies. (authors)

  10. Heat Capacity Analysis Report

    Findikakis, A.

    2004-01-01

    The purpose of this report is to provide heat capacity values for the host and surrounding rock layers for the waste repository at Yucca Mountain. The heat capacity representations provided by this analysis are used in unsaturated zone (UZ) flow, transport, and coupled processes numerical modeling activities, and in thermal analyses as part of the design of the repository to support the license application. Among the reports that use the heat capacity values estimated in this report are the ''Multiscale Thermohydrologic Model'' report, the ''Drift Degradation Analysis'' report, the ''Ventilation Model and Analysis Report, the Igneous Intrusion Impacts on Waste Packages and Waste Forms'' report, the ''Dike/Drift Interactions report, the Drift-Scale Coupled Processes (DST and TH Seepage) Models'' report, and the ''In-Drift Natural Convection and Condensation'' report. The specific objective of this study is to determine the rock-grain and rock-mass heat capacities for the geologic stratigraphy identified in the ''Mineralogic Model (MM3.0) Report'' (BSC 2004 [DIRS 170031], Table 1-1). This report provides estimates of the heat capacity for all stratigraphic layers except the Paleozoic, for which the mineralogic abundance data required to estimate the heat capacity are not available. The temperature range of interest in this analysis is 25 C to 325 C. This interval is broken into three separate temperature sub-intervals: 25 C to 95 C, 95 C to 114 C, and 114 C to 325 C, which correspond to the preboiling, trans-boiling, and postboiling regimes. Heat capacity is defined as the amount of energy required to raise the temperature of a unit mass of material by one degree (Nimick and Connolly 1991 [DIRS 100690], p. 5). The rock-grain heat capacity is defined as the heat capacity of the rock solids (minerals), and does not include the effect of water that exists in the rock pores. By comparison, the rock-mass heat capacity considers the heat capacity of both solids and pore

  11. Implications of Model Structure and Detail for Utility Planning. Scenario Case Studies using the Resource Planning Model

    Mai, Trieu [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Barrows, Clayton [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Lopez, Anthony [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hale, Elaine [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Dyson, Mark [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Eurek, Kelly [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-04-23

    We examine how model investment decisions change under different model configurations and assumptions related to renewable capacity credit, the inclusion or exclusion of operating reserves, dispatch period sampling, transmission power flow modeling, renewable spur line costs, and the ability of a planning region to import and export power. For all modeled scenarios, we find that under market conditions where new renewable deployment is predominantly driven by renewable portfolio standards, model representations of wind and solar capacity credit and interactions between balancing areas are most influential in avoiding model investments in excess thermal capacity. We also compare computation time between configurations to evaluate tradeoffs between computational burden and model accuracy. From this analysis, we find that certain advanced dispatch representations (e.g., DC optimal power flow) can have dramatic adverse effects on computation time but can be largely inconsequential to model investment outcomes, at least at the renewable penetration levels modeled. Finally, we find that certain underappreciated aspects of new capacity investment decisions and model representations thereof, such as spur lines for new renewable capacity, can influence model outcomes particularly in the renewable technology and location chosen by the model. Though this analysis is not comprehensive and results are specific to the model region, input assumptions, and optimization-modeling framework employed, the findings are intended to provide a guide for model improvement opportunities.

  12. Capacity value evaluation of photovoltaic power generation

    Kurihara, I.

    1993-01-01

    The paper presents an example of capacity value (kW-value) evaluation of photovoltaic generation from power companies generation planning point of view. The method actually applied to evaluate the supplying capability of conventional generation plants is briefly described. 21 figs, 1 tab

  13. Prospects for OPEC capacity

    Adelman, M.A.

    1995-01-01

    OPEC capacity is not exogenous, but responds to demand. Price increases have not been caused by capacity shortages. OPEC nations find it hard to set aside even very small portions of their revenues for oil investment, despite its extreme profitability. Foreign investors face high risks. Production sharing makes their after-tax return even more unstable. (author)

  14. Uncertainty in adaptive capacity

    Neil Adger, W.; Vincent, K.

    2005-01-01

    The capacity to adapt is a critical element of the process of adaptation: it is the vector of resources that represent the asset base from which adaptation actions can be made. Adaptive capacity can in theory be identified and measured at various scales, from the individual to the nation. The assessment of uncertainty within such measures comes from the contested knowledge domain and theories surrounding the nature of the determinants of adaptive capacity and the human action of adaptation. While generic adaptive capacity at the national level, for example, is often postulated as being dependent on health, governance and political rights, and literacy, and economic well-being, the determinants of these variables at national levels are not widely understood. We outline the nature of this uncertainty for the major elements of adaptive capacity and illustrate these issues with the example of a social vulnerability index for countries in Africa. (authors)

  15. Optimization of line configuration and balancing for flexible machining lines

    Liu, Xuemei; Li, Aiping; Chen, Zurui

    2016-05-01

    Line configuration and balancing is to select the type of line and allot a given set of operations as well as machines to a sequence of workstations to realize high-efficiency production. Most of the current researches for machining line configuration and balancing problems are related to dedicated transfer lines with dedicated machine workstations. With growing trends towards great product variety and fluctuations in market demand, dedicated transfer lines are being replaced with flexible machining line composed of identical CNC machines. This paper deals with the line configuration and balancing problem for flexible machining lines. The objective is to assign operations to workstations and find the sequence of execution, specify the number of machines in each workstation while minimizing the line cycle time and total number of machines. This problem is subject to precedence, clustering, accessibility and capacity constraints among the features, operations, setups and workstations. The mathematical model and heuristic algorithm based on feature group strategy and polychromatic sets theory are presented to find an optimal solution. The feature group strategy and polychromatic sets theory are used to establish constraint model. A heuristic operations sequencing and assignment algorithm is given. An industrial case study is carried out, and multiple optimal solutions in different line configurations are obtained. The case studying results show that the solutions with shorter cycle time and higher line balancing rate demonstrate the feasibility and effectiveness of the proposed algorithm. This research proposes a heuristic line configuration and balancing algorithm based on feature group strategy and polychromatic sets theory which is able to provide better solutions while achieving an improvement in computing time.

  16. State of technology, system and solution supporting on-line maintenance - company's activities and products

    Nishitani, Junichi; Shimizu, Shunichi; Higasa, Hisakazu

    2010-01-01

    The new inspection system based on operator's maintenance and monitoring program of nuclear power plants was introduced in Japan more than one year ago and recommended on-line maintenance (maintenance during operation) will be carried out to increase capacity factor with safe and reliable operation of the plant. In this feature article, nine experts described the state of technology, system and solution supporting on-line maintenance - company's activities and products. These were titled as 'MHI's technology supporting on-line maintenance'. 'Technology supporting on-line maintenance - Toshiba's activities to upgrade monitoring and diagnostic service and maintenance management', 'AsahiKASEI's activities of on-line maintenance', 'Importance of information sharing of on-line maintenance and its ideal method-function of impact plan of IBM Maximo Asset Management for Nuclear', 'US's on-line maintenance and information systems', 'SmartProcedures realizing safe operation of nuclear power plant - proposal of computerized procedures', 'Ultrasonic leak detection system SDT170', 'Application of infrared thermography for equipment maintenance in nuclear power plant' and 'On-line condition monitoring system - condition eye'. (T. Tanaka)

  17. Transgenic cassava lines carrying heterologous alternative oxidase ...

    Afuape

    2013-07-03

    Jul 3, 2013 ... production of flowers, apomixis (Nassar et al., 2000; ... In order to increase the stress tolerance capacity of ... stress-related procedure due to the activities of auxin ... the evaluation of the transgenic lines for rate of OES .... Some transgenic lines carrying the 35S-AOX fragment amplified using 35S303F1 and.

  18. Representation of Solar Capacity Value in the ReEDS Capacity Expansion Model

    Sigrin, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sullivan, P. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ibanez, E. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, R. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2014-03-01

    An important issue for electricity system operators is the estimation of renewables' capacity contributions to reliably meeting system demand, or their capacity value. While the capacity value of thermal generation can be estimated easily, assessment of wind and solar requires a more nuanced approach due to the resource variability. Reliability-based methods, particularly assessment of the Effective Load-Carrying Capacity, are considered to be the most robust and widely-accepted techniques for addressing this resource variability. This report compares estimates of solar PV capacity value by the Regional Energy Deployment System (ReEDS) capacity expansion model against two sources. The first comparison is against values published by utilities or other entities for known electrical systems at existing solar penetration levels. The second comparison is against a time-series ELCC simulation tool for high renewable penetration scenarios in the Western Interconnection. Results from the ReEDS model are found to compare well with both comparisons, despite being resolved at a super-hourly temporal resolution. Two results are relevant for other capacity-based models that use a super-hourly resolution to model solar capacity value. First, solar capacity value should not be parameterized as a static value, but must decay with increasing penetration. This is because -- for an afternoon-peaking system -- as solar penetration increases, the system's peak net load shifts to later in the day -- when solar output is lower. Second, long-term planning models should determine system adequacy requirements in each time period in order to approximate LOLP calculations. Within the ReEDS model we resolve these issues by using a capacity value estimate that varies by time-slice. Within each time period the net load and shadow price on ReEDS's planning reserve constraint signals the relative importance of additional firm capacity.

  19. production lines

    Jingshan Li

    2000-01-01

    Full Text Available In this work, serial production lines with finished goods buffers operating in the pull regime are considered. The machines are assumed to obey Bernoulli reliability model. The problem of satisfying customers demand is addressed. The level of demand satisfaction is quantified by the due-time performance (DTP, which is defined as the probability to ship to the customer a required number of parts during a fixed time interval. Within this scenario, the definitions of DTP bottlenecks are introduced and a method for their identification is developed.

  20. Fund management plan

    1984-08-01

    This revision of the Fund Management Plan updates the original plan published in May 1983. It is derived from and supplements the Mission Plan of the Office of Civilian Radioactive Waste Management. A major purpose in preparing this Plan is to inform the public about management of the Nuclear Waste Fund and the Interim Storage Fund. The purpose of the Interim Storage Fund is to finance the provision of the Federal interim storage capacity of up to 1900 metric tons of spent nuclear fuel. The Nuclear Waste Fund is a separate account for all revenues and expenditures related to the geological disposal and monitored retrieval storage of civilian radioactive waste

  1. OPEC future capacity expansions

    Sandrea, I.

    2005-01-01

    This conference presentation examined OPEC future capacity expansions including highlights from 2000-2004 from the supply perspective and actions by OPEC; OPEC spare capacity in 2005/2006; medium-term capacity expansion and investments; long-term scenarios, challenges and opportunities; and upstream policies in member countries. Highlights from the supply perspective included worst than expected non-OPEC supply response; non-OPEC supply affected by a number of accidents and strikes; geopolitical tensions; and higher than expected demand for OPEC crude. OPEC's actions included closer relationship with other producers and consumers; capacity expansions in 2004 and 2005/2006; and OPEC kept the market well supplied with crude in 2004. The presentation also provided data using graphical charts on OPEC net capacity additions until 2005/2006; OPEC production versus spare capacity from 2003 to 2005; OPEC production and capacity to 2010; and change in required OPEC production from 2005-2020. Medium term expansion to 2010 includes over 60 projects. Medium-term risks such as project execution, financing, costs, demand, reserves, depletion, integration of Iraq, and geopolitical tensions were also discussed. The presentation concluded that in the long term, large uncertainties remain; the peak of world supply is not imminent; and continued and enhanced cooperation is essential to market stability. tabs., figs

  2. Reconstruction of railway energy lines; Rekonstruktion von Bahnenergieleitungen

    Rothe, Matthias [DB Energie Gmbh, Berlin (Germany); Wahlen, Manfred [DB Energie Gmbh, Koeln (Germany)

    2013-06-15

    As is the case for other overhead lines, 110 kV railway energy lines are assumed to have a service life of 80 years. When this service life ends or the lines are adapted to the state of the art as necessary, all components of the overhead line are renewed. For the reconstruction of railway energy lines, the specifications laid down in planning and environmental laws, operational management aspects and the local ambient and development situation are decisive project planning parameters. (orig.)

  3. Vedr.: Military capacity building

    Larsen, Josefine Kühnel; Struwe, Lars Bangert

    2013-01-01

    Military capacity building has increasingly become an integral part of Danish defence. Military capacity is a new way of thinking Danish defence and poses a new set of challenges and opportunities for the Danish military and the Political leadership. On the 12th of december, PhD. Candidate Josefine...... Kühnel Larsen and researcher Lars Bangert Struwe of CMS had organized a seminar in collaboration with Royal Danish Defense Colleg and the East African Security Governance Network. The seminar focused on some of the risks involved in Military capacity building and how these risks are dealt with from...

  4. Line facilities outline

    1998-08-01

    This book deals with line facilities. The contents of this book are outline line of wire telecommunication ; development of line, classification of section of line and theory of transmission of line, cable line ; structure of line, line of cable in town, line out of town, domestic cable and other lines, Optical communication ; line of optical cable, transmission method, measurement of optical communication and cable of the sea bottom, Equipment of telecommunication line ; telecommunication line facilities and telecommunication of public works, construction of cable line and maintenance and Regulation of line equipment ; regulation on technique, construction and maintenance.

  5. Evaluating Capacity Development

    She also had the dubious pleasure of checking and correcting the text numerous ... Has your organization received training or other types of support for capacity ...... processors, and consumer groups in its research and development work.

  6. Effects of capacity constraints on the motion pattern of an autonomous orchard sprayer

    Bochtis, D.D.; Vougioukas, S.G.; Griepentrog, Hans-Werner

    Orchard farming operations are very promising for automated systems implementation due to the semi-controlled environment that they are executed. Researches on autonomous orchard vehicles have been madden from many research teams the last years. Although, there is a lot of work that has been done...... which computes the routes that the vehicle has to follow as well as the optimal locations of the facilities in order to minimize the total operation's time. An autonomous tractor was used as the test platform. For the off-line testing of the planned operations as well as for the evaluation...... concerning the navigation of these vehicles, there is a lack of efficient mission planning for the operations that they execute. In this paper, orchard operations with capacity restrictions, such us spraying operation, are studied. For this kind of operations, a combinatorial optimization method is used...

  7. Revisiting Absorptive Capacity

    de Araújo, Ana Luiza Lara; Ulhøi, John Parm; Lettl, Christopher

    Absorptive capacity has mostly been perceived as a 'passive' outcome of R&D investments. Recently, however, a growing interest into its 'proactive' potentials has emerged. This paper taps into this development and proposes a dynamic model for conceptualizing the determinants of the complementary...... learning processes of absorptive capacity, which comprise combinative and adaptive capabilities. Drawing on survey data (n=169), the study concludes that combinative capabilities primarily enhance transformative and exploratory learning processes, while adaptive capabilities strengthen all three learning...

  8. Building Capacity in the Public Utility Sectors of Basra, Iraq

    Trainor, Tim; Henderson, Dale

    2007-01-01

    ... in provincial reconstruction efforts. Specifically, the mission was to assist in building the capacity of the public sector utility leadership in project prioritization, project planning and project management in order to enhance...

  9. Public Affairs Capacity Building: A Soft Tool for Combatant Commanders

    Salata, Jason P

    2008-01-01

    Public affairs capacity building is a valuable soft component of the Combatant Commander's Theater Campaign Plan that builds habitual relationships, fosters transparency, and enhances the ability to shape the AOR...

  10. Parallel Lines

    James G. Worner

    2017-05-01

    Full Text Available James Worner is an Australian-based writer and scholar currently pursuing a PhD at the University of Technology Sydney. His research seeks to expose masculinities lost in the shadow of Australia’s Anzac hegemony while exploring new opportunities for contemporary historiography. He is the recipient of the Doctoral Scholarship in Historical Consciousness at the university’s Australian Centre of Public History and will be hosted by the University of Bologna during 2017 on a doctoral research writing scholarship.   ‘Parallel Lines’ is one of a collection of stories, The Shapes of Us, exploring liminal spaces of modern life: class, gender, sexuality, race, religion and education. It looks at lives, like lines, that do not meet but which travel in proximity, simultaneously attracted and repelled. James’ short stories have been published in various journals and anthologies.

  11. Buyer-supplier relationships and planning solutions

    Hvolby, H.H.; Trienekens, J.H.; Steger-Jensen, K.

    2007-01-01

    The paper focuses on supply chain relationships and segmented planning and ICT concepts. Major supplier segments are distinguished based on literature: capacity suppliers, standard suppliers, system suppliers and key suppliers. Next, current supply chain planning solutions are distinguished: vendor

  12. Opportunities and Benefits for Increasing Transmission Capacity between the US Eastern and Western Interconnections

    Figueroa-Acevedo, Armando L.

    Historically, the primary justification for building wide-area transmission lines in the US and around the world has been based on reliability and economic criteria. Today, the influence of renewable portfolio standards (RPS), Environmental Protection Agency (EPA) regulations, transmission needs, load diversity, and grid flexibility requirements drives interest in high capacity wide-area transmission. By making use of an optimization model to perform long-term (15 years) co-optimized generation and transmission expansion planning, this work explored the benefits of increasing transmission capacity between the US Eastern and Western Interconnections under different policy and futures assumptions. The model assessed tradeoffs between investments in cross-interconnection HVDC transmission, AC transmission needs within each interconnection, generation investment costs, and operational costs, while satisfying different policy compliance constraints. Operational costs were broken down into the following market products: energy, up-/down regulation reserve, and contingency reserve. In addition, the system operating flexibility requirements were modeled as a function of net-load variability so that the flexibility of the non-wind/non-solar resources increases with increased wind and solar investment. In addition, planning reserve constraints are imposed under the condition that they be deliverable to the load. Thus, the model allows existing and candidate generation resources for both operating reserves and deliverable planning reserves to be shared throughout the interconnections, a feature which significantly drives identification of least-cost investments. This model is used with a 169-bus representation of the North American power grid to design four different high-capacity wide-area transmission infrastructures. Results from this analysis suggest that, under policy that imposes a high-renewable future, the benefits of high capacity transmission between the Eastern and

  13. Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 27. Biogas construction plan in Jeruk Manis Village in Lombok, West Nusa Tenggara

    Natsir, A. [University of Mataram, Mataram (Indonesia)

    2011-10-15

    The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara (WNT) and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. The proposed small-scale renewable energy project to be developed under the Casindo Technical Working Group IV in West Nusa Tenggara is focused on household biogas. The project will be implemented in Jeruk Manis, which has been selected as the target location for the implementation of the renewable energy project in the program Casindo. Administratively, the village of 'Jeruk Manis' is located in the district Sikur, East Lombok, West Nusa Tenggara province. The number of households eligible as the target of the program in Jeruk Manis is 63. To implement the project, the Casindo team in WNT has partnered with Hivos and its BIRU program (Biogas Rumah program or Indonesia Domestic Biogas Programme). The biogas digester construction will be conducted by BIRU Lombok, in collaboration with a construction partner organization called Yayasan Mandiri Membangun Masyarakat Sejahtera (YM3S) and managed by the Casindo project team from the Faculty of Engineering at the University of Mataram. If the project is implemented, it will bring many benefits for poor people in the target location, which are likely to be sustained for a long time. While the benefits of developing biogas in the selected low-income location are obvious and abundant, there are also many challenges. The main problem for the proposed project is finding other interested funders to support the building of household biogas, as the financial capacity of the target households is very small.

  14. A general approach to decomposable bi-capacities

    Saminger, S.; Mesiar, Radko

    2003-01-01

    Roč. 39, č. 5 (2003), s. 631-642 ISSN 0023-5954 R&D Projects: GA ČR GA402/04/1026 Institutional research plan: CEZ:AV0Z1075907 Keywords : bi-capacity * cumulative prospect theory * decomposable capacity Subject RIV: BA - General Mathematics Impact factor: 0.319, year: 2003

  15. Defense plan of Hydro-Quebec for extreme contingencies

    Trudel, Guilles; Bernard, Serge; Portales, Esteban

    2000-01-01

    In the last years, Hydro-Quebec it undertook an important program to improve the dependability of their net of energy transport. They concentrated the efforts on increasing the capacity of the net resist in the event of carries to an extreme contingency caused in general by multiple incidents or for successive disconnection of the lines of energy transport. To neutralize these contingencies, Hydro-Quebec it adopted a series of special measures that are contained under the general title of Plan of Defense for Extreme Contingencies. The objective of this plan is to detect the incidents that surpass the capacity of the net. It is completely automatic and it is based mainly in: A system of automatic disconnection of generation and tele-shot of loads; A system of automatic maneuver (opening and closing) of inductances shunt of 735 kw; A system of disconnection of loads for low voltage; A system of disconnection of loads for low frequency. The present document summarizes the orientations that there is taking Hydro-Quebec to protect its net in the event of extreme contingencies and it describes the different automatism that they are adopts, in particular the system automatic disconnection of generation and tele-shot of loads (RPTC) that is one of the main components of the defense plan. The system RPTC detects the simultaneous loss of several lines directly in 15 substations of 735 kw. It understands four places of automatic disconnection of generation and a centralized system of tele-shot of loads

  16. The Practice of Guangzhou Port Planning Environmental Impact Assessment

    Wang, Ning; Zhao, Junjie; Shou, Youping; Qiao, Jianzhe; Dong, Shipei; Zhang, Lu

    2018-01-01

    In this paper, the effects of the implementation of Guangzhou port plan were analyzed from hydrological condition, water environment and ecological environment. Regional water environmental carrying capacity was analyzed. Guangzhou port is a main port in the coast of China, it is an important port of foreign trade in south China, it is an important port for energy supplies and raw materials in Guangdong province [1]. With the shipping channel condition improvement and the construction of large specialized container port area, Guangzhou port will gradually become trunk line port of container transport in south China.

  17. Concentrated fed-batch cell culture increases manufacturing capacity without additional volumetric capacity.

    Yang, William C; Minkler, Daniel F; Kshirsagar, Rashmi; Ryll, Thomas; Huang, Yao-Ming

    2016-01-10

    Biomanufacturing factories of the future are transitioning from large, single-product facilities toward smaller, multi-product, flexible facilities. Flexible capacity allows companies to adapt to ever-changing pipeline and market demands. Concentrated fed-batch (CFB) cell culture enables flexible manufacturing capacity with limited volumetric capacity; it intensifies cell culture titers such that the output of a smaller facility can rival that of a larger facility. We tested this hypothesis at bench scale by developing a feeding strategy for CFB and applying it to two cell lines. CFB improved cell line A output by 105% and cell line B output by 70% compared to traditional fed-batch (TFB) processes. CFB did not greatly change cell line A product quality, but it improved cell line B charge heterogeneity, suggesting that CFB has both process and product quality benefits. We projected CFB output gains in the context of a 2000-L small-scale facility, but the output was lower than that of a 15,000-L large-scale TFB facility. CFB's high cell mass also complicated operations, eroded volumetric productivity, and showed our current processes require significant improvements in specific productivity in order to realize their full potential and savings in manufacturing. Thus, improving specific productivity can resolve CFB's cost, scale-up, and operability challenges. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Warehouse operations planning model for Bausch & Lomb

    Atilgan, Ceren

    2009-01-01

    Operations planning is a major part of the Sales& Operations Planning (S&OP) process. It provides an overview on the operations capacity requirements by considering the supply and demand plan. However, Bausch& Lomb does not have a structured operations planning process for their warehouse

  19. Capacity Maximizing Constellations

    Barsoum, Maged; Jones, Christopher

    2010-01-01

    Some non-traditional signal constellations have been proposed for transmission of data over the Additive White Gaussian Noise (AWGN) channel using such channel-capacity-approaching codes as low-density parity-check (LDPC) or turbo codes. Computational simulations have shown performance gains of more than 1 dB over traditional constellations. These gains could be translated to bandwidth- efficient communications, variously, over longer distances, using less power, or using smaller antennas. The proposed constellations have been used in a bit-interleaved coded modulation system employing state-ofthe-art LDPC codes. In computational simulations, these constellations were shown to afford performance gains over traditional constellations as predicted by the gap between the parallel decoding capacity of the constellations and the Gaussian capacity

  20. Dual capacity reciprocating compressor

    Wolfe, Robert W.

    1984-01-01

    A multi-cylinder compressor 10 particularly useful in connection with northern climate heat pumps and in which different capacities are available in accordance with reversing motor 16 rotation is provided with an eccentric cam 38 on a crank pin 34 under a fraction of the connecting rods, and arranged for rotation upon the crank pin between opposite positions 180.degree. apart so that with cam rotation on the crank pin such that the crank throw is at its normal maximum value all pistons pump at full capacity, and with rotation of the crank shaft in the opposite direction the cam moves to a circumferential position on the crank pin such that the overall crank throw is zero. Pistons 24 whose connecting rods 30 ride on a crank pin 36 without a cam pump their normal rate with either crank rotational direction. Thus a small clearance volume is provided for any piston that moves when in either capacity mode of operation.

  1. Visual attention capacity

    Habekost, Thomas; Starrfelt, Randi

    2009-01-01

    Psychophysical studies have identified two distinct limitations of visual attention capacity: processing speed and apprehension span. Using a simple test, these cognitive factors can be analyzed by Bundesen's Theory of Visual Attention (TVA). The method has strong specificity and sensitivity......, and measurements are highly reliable. As the method is theoretically founded, it also has high validity. TVA-based assessment has recently been used to investigate a broad range of neuropsychological and neurological conditions. We present the method, including the experimental paradigm and practical guidelines...... to patient testing, and review existing TVA-based patient studies organized by lesion anatomy. Lesions in three anatomical regions affect visual capacity: The parietal lobes, frontal cortex and basal ganglia, and extrastriate cortex. Visual capacity thus depends on large, bilaterally distributed anatomical...

  2. VT Digital Line Graph Miscellaneous Transmission Lines

    Vermont Center for Geographic Information — (Link to Metadata) This datalayer is comprised of Miscellaineous Transmission Lines. Digital line graph (DLG) data are digital representations of cartographic...

  3. Value for railway capacity

    Sameni, Melody Khadem; Preston, John M.

    2012-01-01

    to analyze the efficiency of operators in transforming inputs of allocated capacity of infrastructure and franchise payments into valuable passenger service outputs while avoiding delays. By addressing operational and economic aspects of capacity utilization simultaneously, the paper deviates from existing...... DEA work on the economic efficiency of railways by considering a new combination of input-output that also incorporates quality of service. The constant and variable returns to scale models are applied to the case study of franchised passenger operators in Great Britain. The follow-up Tobit regression...

  4. The line makes the difference: line managers as effective HRM partners

    Bos-Nehles, Anna Christina

    2010-01-01

    The HR role of line managers is highly discussed and criticized but little empirically researched. It is argued that line managers are not able to effectively implement HR practices because they do not have the desire, capacity and competences needed to perform well and lack support and policies &

  5. Dynamic Line Rating - Technologies and Challenges of PMU on Overhead Lines

    Alvarez, David; Rosero, Javier; Silva, Filipe Miguel Faria da

    2016-01-01

    for line rating computation and monitoring are identified, these are: sensors, communications, management information system and information analysis tools, which are part of integral dynamic line rating systems. Finally, the benefits and challenges of using phasor measurement units for real time capacity...

  6. Strategic production line synchronisation

    Hattingh, Teresa

    2016-08-01

    Full Text Available A study was conducted at the sole global producer of suspension struts for a particular vehicle manufacturer. This supplier is currently able to meet customer demand. However, it does so because of a large finished goods and work-in-progress (WIP inventory. The plant operates two production processes that are separated by a large buffer of WIP, which essentially decouples the production processes. This study aimed to reduce this WIP buffer; this would require the processes to become synchronised, bearing in mind that the reliability of delivery should not decrease. A tool that considers time, quality, and machine capacity was developed to assess the impact of line synchronisation on company performance figures. It was found that line synchronisation produced several benefits for the supplier, including batch size reduction, lower inventory levels, and associated shorter lead times. This further allowed the supplier to improve flow in the plant by introducing a pull system. Improved visual oversight could lead to further improved problem-solving and innovation.

  7. Capacity in the energy underwriting market - an overview

    Mulhall, L.

    1992-01-01

    It is important to clarify the different definitions of capacity, and in the insurance business this work has two distinct interpretations. The capacity of a Lloyd's syndicate is described by its ability to write premium income. Of more interest is the maximum ability and willingness of an underwriter, whether Lloyds's or Company, to commit itself to catastrophe loss policies. Or put more simply, what is the size of their line? It is this capacity for covering high value catastrophic exposure or Target Risks that will be discussed using the definition that capacity in this case is: ''The ability of insurance markets to cover any single maximum loss''. (Author)

  8. Markets and Institutional Capacity

    Ingemann, Jan Holm

    2010-01-01

    Adequate explanations concerning the introduction of production and consumption of organic food in Denmark imply the necessity to engage a certain understanding of markets. Markets should subsequently not be seen as entities nor places but as complex relations between human actors. Further......, the establishment, maintenance and development of markets are depending on the capacity of the actors to enter into continuous and enhancing interplay....

  9. The U-line line balancing problem

    Miltenburg, G.J.; Wijngaard, J.

    1994-01-01

    The traditional line balancing (LB) problem considers a production line in which stations are arranged consecutively in a line. A balance is determined by grouping tasks into stations while moving forward (or backward) through a precedence network. Recently many production lines are being arranged

  10. Cognitive capacities for cooking in chimpanzees

    Warneken, Felix; Rosati, Alexandra G.

    2015-01-01

    The transition to a cooked diet represents an important shift in human ecology and evolution. Cooking requires a set of sophisticated cognitive abilities, including causal reasoning, self-control and anticipatory planning. Do humans uniquely possess the cognitive capacities needed to cook food? We address whether one of humans' closest relatives, chimpanzees (Pan troglodytes), possess the domain-general cognitive skills needed to cook. Across nine studies, we show that chimpanzees: (i) prefer...

  11. Data Management Plan

    Hansen, Ernst Jan de Place; Sørensen, Nils Lykke

    2016-01-01

    This document describes the Data Management Plan (DMP) (second version), relating to RIBuild WP8, deliverable D8.1. It draws the first lines for how data can be made findable, accessible, interoperable and re-usable after the project period.......This document describes the Data Management Plan (DMP) (second version), relating to RIBuild WP8, deliverable D8.1. It draws the first lines for how data can be made findable, accessible, interoperable and re-usable after the project period....

  12. Robustness indicators and capacity models for railway networks

    Jensen, Lars Wittrup

    In a world continuous striving for higher mobility and the use of more sustainable modes of transport, there is a constant pressure on utilising railway capacity better and, at the same time, obtaining a high robustness against delays. During the planning of railway operations and infrastructure ....... This has motivated the research conducted and described in this thesis, where the objective has been to develop and improve existing methods to achieve timetable and infrastructure plans with robust capacity utilisation aimed at the strategic and early tactical planning phases....

  13. Enterprise resource planning for hospitals

    van Merode, Godefridus G.; Groothuis, Siebren; Hasman, Arie

    2004-01-01

    Integrated hospitals need a central planning and control system to plan patients' processes and the required capacity. Given the changes in healthcare one can ask the question what type of information systems can best support these healthcare delivery organizations. We focus in this review on the

  14. Enterprise resource planning for hospitals

    Merode, van G.G.; Groothuis, S.; Hasman, A.

    2004-01-01

    Integrated hospitals need a central planning and control system to plan patients’ processes and the required capacity. Given the changes in healthcare one can ask the question what type of information systems can best support these healthcare delivery organizations. We focus in this review on the

  15. Health Workforce Planning

    Al-Sawai, Abdulaziz; Al-Shishtawy, Moeness M.

    2015-01-01

    In most countries, the lack of explicit health workforce planning has resulted in imbalances that threaten the capacity of healthcare systems to attain their objectives. This has directed attention towards the prospect of developing healthcare systems that are more responsive to the needs and expectations of the population by providing health planners with a systematic method to effectively manage human resources in this sector. This review analyses various approaches to health workforce planning and presents the Six-Step Methodology to Integrated Workforce Planning which highlights essential elements in workforce planning to ensure the quality of services. The purpose, scope and ownership of the approach is defined. Furthermore, developing an action plan for managing a health workforce is emphasised and a reviewing and monitoring process to guide corrective actions is suggested. PMID:25685381

  16. Hopi Sustainable Energy Plan

    Norman Honie, Jr.; Margie Schaff; Mark Hannifan

    2004-08-01

    The Hopi Tribal Government as part of an initiative to ?Regulate the delivery of energy and energy services to the Hopi Reservation and to create a strategic business plan for tribal provision of appropriate utility, both in a manner that improves the reliability and cost efficiency of such services,? established the Hopi Clean Air Partnership Project (HCAPP) to support the Tribe?s economic development goals, which is sensitive to the needs and ways of the Hopi people. The Department of Energy (DOE) funded, Formation of Hopi Sustainable Energy Program results are included in the Clean Air Partnership Report. One of the Hopi Tribe?s primary strategies to improving the reliability and cost efficiency of energy services on the Reservation and to creating alternative (to coal) economic development opportunities is to form and begin implementation of the Hopi Sustainable Energy Program. The Hopi Tribe through the implementation of this grant identified various economic opportunities available from renewable energy resources. However, in order to take advantage of those opportunities, capacity building of tribal staff is essential in order for the Tribe to develop and manage its renewable energy resources. As Arizona public utilities such as APS?s renewable energy portfolio increases the demand for renewable power will increase. The Hopi Tribe would be in a good position to provide a percentage of the power through wind energy. It is equally important that the Hopi Tribe begin a dialogue with APS and NTUA to purchase the 69Kv transmission on Hopi and begin looking into financing options to purchase the line.

  17. Joint optimization of maintenance, buffers and machines in manufacturing lines

    Nahas, Nabil; Nourelfath, Mustapha

    2018-01-01

    This article considers a series manufacturing line composed of several machines separated by intermediate buffers of finite capacity. The goal is to find the optimal number of preventive maintenance actions performed on each machine, the optimal selection of machines and the optimal buffer allocation plan that minimize the total system cost, while providing the desired system throughput level. The mean times between failures of all machines are assumed to increase when applying periodic preventive maintenance. To estimate the production line throughput, a decomposition method is used. The decision variables in the formulated optimal design problem are buffer levels, types of machines and times between preventive maintenance actions. Three heuristic approaches are developed to solve the formulated combinatorial optimization problem. The first heuristic consists of a genetic algorithm, the second is based on the nonlinear threshold accepting metaheuristic and the third is an ant colony system. The proposed heuristics are compared and their efficiency is shown through several numerical examples. It is found that the nonlinear threshold accepting algorithm outperforms the genetic algorithm and ant colony system, while the genetic algorithm provides better results than the ant colony system for longer manufacturing lines.

  18. Do you have a Plan B?

    Dahlberg, Rasmus

    2017-01-01

    This study explores adaptive capacities in infrastructure preparedness planning from a resilience approach using the bridge between Denmark and Sweden as a case. First, a theoretical framework anchors adaptive capacity in a more general resilience discourse focusing on flexibility and adaptive...... capacity with emphasis on citizens’ ability to interpret information and adjust their behaviour without prior planning and training or instructions. Then, findings from a small qualitative study (n = 45) of the perception of commuters and travellers of the responsibilities and contingencies involved...

  19. Neuronal discrimination capacity

    Deng Yingchun; Williams, Peter; Feng Jianfeng; Liu Feng

    2003-01-01

    We explore neuronal mechanisms of discriminating between masked signals. It is found that when the correlation between input signals is zero, the output signals are separable if and only if input signals are separable. With positively (negatively) correlated signals, the output signals are separable (mixed) even when input signals are mixed (separable). Exact values of discrimination capacity are obtained for two most interesting cases: the exactly balanced inhibitory and excitatory input case and the uncorrelated input case. Interestingly, the discrimination capacity obtained in these cases is independent of model parameters, input distribution and is universal. Our results also suggest a functional role of inhibitory inputs and correlated inputs or, more generally, the large variability of efferent spike trains observed in in vivo experiments: the larger the variability of efferent spike trains, the easier it is to discriminate between masked input signals

  20. Seismic capacity of switchgear

    Bandyopadhyay, K.; Hofmayer, C.; Kassir, M.; Pepper, S.

    1989-01-01

    As part of a component fragility program sponsored by the USNRC, BNL has collected existing information on the seismic capacity of switchgear assemblies from major manufacturers. Existing seismic test data for both low and medium voltage switchgear assemblies have been evaluated and the generic results are presented in this paper. The failure modes are identified and the corresponding generic lower bound capacity levels are established. The test response spectra have been used as a measure of the test vibration input. The results indicate that relays chatter at a very low input level at the base of the switchgear cabinet. This change of state of devices including relays have been observed. Breaker tripping occurs at a higher vibration level. Although the structural failure of internal elements have been noticed, the overall switchgear cabinet structure withstands a high vibration level. 5 refs., 2 figs., 2 tabs

  1. Neuronal discrimination capacity

    Deng Yingchun [Department of Mathematics, Hunan Normal University 410081, Changsha (China); COGS, University of Sussex at Brighton, BN1 9QH (United Kingdom); Williams, Peter; Feng Jianfeng [COGS, University of Sussex at Brighton, BN1 9QH (United Kingdom); Liu Feng [COGS, University of Sussex at Brighton, BN1 9QH (United Kingdom); Physics Department, Nanjing University (China)

    2003-12-19

    We explore neuronal mechanisms of discriminating between masked signals. It is found that when the correlation between input signals is zero, the output signals are separable if and only if input signals are separable. With positively (negatively) correlated signals, the output signals are separable (mixed) even when input signals are mixed (separable). Exact values of discrimination capacity are obtained for two most interesting cases: the exactly balanced inhibitory and excitatory input case and the uncorrelated input case. Interestingly, the discrimination capacity obtained in these cases is independent of model parameters, input distribution and is universal. Our results also suggest a functional role of inhibitory inputs and correlated inputs or, more generally, the large variability of efferent spike trains observed in in vivo experiments: the larger the variability of efferent spike trains, the easier it is to discriminate between masked input signals.

  2. PAYMENT CAPACITY SENSITIVITY FACTORS

    Daniel BRÎNDESCU – OLARIU

    2014-01-01

    The current study focuses on the sensitivity of the corporate payment capacity. Through the nature of the subject, the research is based on simulating variations of the forecasted cash-flows of the companies included in the sample. The study employs 391 forecasted yearly cash-flows statements collected from 50 companies from Timis County (Romania), as well as the detailed hypotheses of the forecasts. The results of the study facilitate the determination and classification of the main se...

  3. Options on capacity imbalance

    Roggen, M.

    2002-01-01

    Since the start of this year, the Dutch energy company Nuon has been using a computer system to formulate real-time responses to national capacity imbalances in the electricity supply market. The work earns Nuon a fixed fee from TenneT (Dutch Transmission System Operator) and ensures a more stable imbalance price for everyone. The key to success has been the decision to start the project from scratch [nl

  4. CSTI High Capacity Power

    Winter, J.M.

    1989-01-01

    The SP-100 program was established in 1983 by DOD, DOE, and NASA as a joint program to develop the technology necessary for space nuclear power systems for military and civil application. During FY-86 and 87, the NASA SP-100 Advanced Technology Program was devised to maintain the momentum of promising technology advancement efforts started during Phase 1 of SP-100 and to strengthen, in key areas, the chances for successful development and growth capability of space nuclear reactor power systems for future space applications. In FY-88, the Advanced Technology Program was incorporated into NASA's new Civil Space Technology Initiative (CSTI). The CSTI Program was established to provide the foundation for technology development in automation and robotics, information, propulsion, and power. The CSTI High Capacity Power Program builds on the technology efforts of the SP-100 program, incorporates the previous NASA SP-100 Advanced Technology project, and provides a bridge to NASA Project Pathfinder. The elements of CSTI High Capacity Power development include Conversion Systems, Thermal Management, Power Management, System Diagnostics, and Environmental Interactions. Technology advancement in all areas, including materials, is required to assure the high reliability and 7 to 10 year lifetime demanded for future space nuclear power systems. The overall program will develop and demonstrate the technology base required to provide a wide range of modular power systems as well as allowing mission independence from solar and orbital attitude requirements. Several recent advancements in CSTI High Capacity power development will be discussed

  5. Practical use of the UIC 406 capacity leaflet by including timetable tools in the investigations

    Landex, Alex; Kaas, Anders H.; Schittenhelm, Bernd

    2006-01-01

    This paper describes the relatively new UIC 406 method for calculating capacity consumption on railway lines. The UIC 406 method is an easy and effective way of calculating the capacity consumption, but it is possible to expound the UIC 406 method in different ways which can lead to different...... capacity consumptions. This paper describes how the UIC 406 method is expounded in Denmark. The paper describes the importance of choosing the right length of the line sections examined and how line sections with multiple track sections are examined. Furthermore, the possibility of using idle capacity...

  6. Financial capacity in older adults: a growing concern for clinicians.

    Gardiner, Paul A; Byrne, Gerard J; Mitchell, Leander K; Pachana, Nancy A

    2015-02-02

    Older people with cognitive impairment and/or dementia may be particularly vulnerable to diminished financial decision-making capacity. Financial capacity refers to the ability to satisfactorily manage one's financial affairs in a manner consistent with personal self-interest and values. Impairment of financial capacity makes the older individual vulnerable to financial exploitation, may negatively affect their family's financial situation and places strain on relationships within the family. Clinicians are often on the front line of responding to queries regarding decision-making capacity, and clinical evaluation options are often not well understood. Assessment of financial capacity should include formal objective assessment in addition to a clinical interview and gathering contextual data. Development of a flexible, empirically supported and clinically relevant assessment approach that spans all dimensions of financial capacity yet is simple enough to be used by non-specialist clinicians is needed.

  7. Competence building capacity shortage

    Doorman, Gerard; Wangensteen, Ivar; Bakken, Bjoern

    2005-02-01

    The objective of the project 'Competence Building Capacity Shortage' has been 'to increase knowledge about central approaches aimed at solving the peaking capacity problem in restructured power systems'. With respect to reserve markets, a model was developed in the project to analyze the relations between reserve requirements and prices in the spot and reserve markets respectively. A mathematical model was also developed and implemented, which also includes the balance market, and has a good ability to predict the relations between these markets under various assumptions. With some further development, this model can be used fore realistic analyses of these markets in a Nordic context. It was also concluded that certain system requirements with respect to frequency and time deviation can be relaxed without adverse effects. However, the requirements to system bias, Frequency Activated Operating Reserves and Frequency Activated Contingency Reserves cannot be relaxed, the latter because they must cover the dimensioning fault in the system. On the other hand, Fast Contingency Reserves can be reduced by removing requirements to national balances. Costs can furthermore be reduced by increasingly adapting a Nordic as opposed to national approach. A model for stepwise power flow was developed in the project, which is especially useful to analyze slow power system dynamics. This is relevant when analysing the effects of reserve requirements. A model for the analysis of the capacity balance in Norway and Sweden was also developed. This model is useful for looking at the future balance under various assumptions regarding e.g. weather conditions, demand growth and the development of the generation system. With respect to the present situation, if there is some price flexibility on the demand side and system operators are able to use reserves from the demand side, the probability for load shedding during the peak load hour is close to zero under the weather conditions after

  8. Increasing transmission capacity : case studies and techniques

    Reisdorff, R.A. [Laminated Wood Systems, NE (United States)

    2007-07-01

    Many companies are stretching the capacities of their mature transmission lines as a result of deregulation in the electric utility industry. Since electric utilities are no longer in control of new generation locations or capacities, their mission has changed from supplying electricity to regional customers to that of the movement of power over their grid. There will also be even more pressure to maximize the thermal capacity of existing transmission lines once the regional transmission operators (RTOs) are in place. Various methods including conductor replacement or increasing structure height are available options to accomplish this. This paper discussed the available methods to increase ground clearance, including structure changeouts; pole top extensions; nip and tuck conductor; adding mid-span structures; and raising structures. Because the actual cost of line outages for maintenance of rebuild work will make many present day work procedures obsolete, the industry is changing to methods of safely increasing the existing structure heights without removing the line from service. The paper also presented the Phaiseraiser product which is a patented system, consisting of double steel members that are either single or multiple piece units which are used to support the raised structure. The paper discussed the product development of the Phaiseraiser product, with reference to wood stubs; pier foundation; pole enforcer methodology; testing; designs; and ordering requirements. Last, the paper discussed a custom designed installation tool package developed by Laminated Wood Systems (LWS); LWS structural analysis; estimated cost for Phaiseraiser installation on an h-frame; labor resources and training; maintenance considerations; completed Phaiseraiser projects; and a case study on the Omaha Public Power District. figs.

  9. Laboratory analysis of phacoemulsifier compliance and capacity.

    Nejad, Mitra; Injev, Valentine P; Miller, Kevin M

    2012-11-01

    To compare the compliance and capacity of 7 fluidics modules used by 6 phacoemulsifiers from 3 manufacturers. Jules Stein Eye Institute, Los Angeles, California, USA. Experimental study. Previous-model and current-model phacoemulsifiers from 3 manufacturers were subjected to laboratory analysis of compliance and capacity. Previous-generation models tested included the Legacy Advantec, Whitestar Sovereign Phacoemulsification System, and Millennium Microsurgical System. Current models tested were the Infiniti Vision System with standard and Intrepid cassettes, Whitestar Signature Phacoemulsification System, and Stellaris Vision Enhancement System. To measure compliance, the aspiration line was connected to an electronic pressure transducer and small volumes of fluid were injected or aspirated. To measure capacity, the space between the distal end of the aspiration line and the pump was filled with methylene blue-dyed fluid. The Legacy was the most compliant phacoemulsifier. The old and new Whitestar systems, Millennium system, and Stellaris system showed similar midrange compliances. The Infiniti Vision System with the Intrepid fluidic management system was the least compliant. The Infiniti cassettes had the greatest capacity, which is a detriment from a surge-control perspective, and Signature cassettes had the least capacity. The Infiniti Intrepid system had the lowest compliance of the 6 units tested, which is optimum from a surge-control perspective. All other things being equal, the Infiniti should have the safest occlusion-break surge response. Mr. Injev is an employee of Alcon Laboratories. Dr. Miller is a consultant to and investigator for Alcon Laboratories. Ms. Nejad has no financial or proprietary interest in any material or method mentioned. Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  10. Synchronous method and engineering tool for the strategic factory planning

    Abdul Rahman, O.; Jaeger, J.; Constantinescu, C.

    2011-01-01

    This paper presents the approach to combine two reference methods and engineering tools, for "Factory Performance and Investment Planning«as well as "Value Added Ideal Production Network Planning". The resulted synchronous method aims to support factories in the strategic planning as well as in the network planning. The corresponding engineering tool is employed for assessment planning, sales planning, capacity planning and production costs planning under the consideration of dynamic and stoc...

  11. Energy modelling and capacity building

    2005-01-01

    The Planning and Economic Studies Section of the IAEA's Department of Nuclear Energy is focusing on building analytical capacity in MS for energy-environmental-economic assessments and for the elaboration of sustainable energy strategies. It offers a variety of analytical models specifically designed for use in developing countries for (i) evaluating alternative energy strategies; (ii) assessing environmental, economic and financial impacts of energy options; (iii) assessing infrastructure needs; (iv) evaluating regional development possibilities and energy trade; (v) assessing the role of nuclear power in addressing priority issues (climate change, energy security, etc.). These models can be used for analysing energy or electricity systems, and to assess possible implications of different energy, environmental or financial policies that affect the energy sector and energy systems. The models vary in complexity and data requirements, and so can be adapted to the available data, statistics and analytical needs of different countries. These models are constantly updated to reflect changes in the real world and in the concerns that drive energy system choices. They can provide thoughtfully informed choices for policy makers over a broader range of circumstances and interests. For example, they can readily reflect the workings of competitive energy and electricity markets, and cover such topics as external costs. The IAEA further offers training in the use of these models and -just as important- in the interpretation and critical evaluation of results. Training of national teams to develop national competence over the full spectrum of models, is a high priority. The IAEA maintains a broad spectrum of databanks relevant to energy, economic and environmental analysis in MS, and make these data available to analysts in MS for use in their own analytical work. The Reference Technology Data Base (RTDB) and the Reference Data Series (RDS-1) are the major vehicles by which we

  12. [Ecotourism carrying capacity of Hangzhou Xixi National Wetland Park in China].

    Li, Rui; Rong, Liang

    2007-10-01

    In this paper, an integrated estimation on the ecotourism carrying capacity of Hangzhou Xixi National Wetland Park in China was made from the aspects of ecological carrying capacity, spatial carrying capacity, facility carrying capacity, management carrying capacity, and psychological carrying capacity. The results indicated that the tourism carrying capacity of the Park was 4 145 - 6 450 persons per day. The rational distance between man and bird was first adopted to determine the ecotourism carrying capacity of wetland, which provided an effective solution both to fully ensure bird safety and to appropriately develop wetland tourism. The estimation of psychological carrying capacity based on tourist satisfaction degree reflected more objectively the extent the tourist demands satisfied at the planning, construction and management of tour places. Such an integrated estimation method based on the distance between man and bird and the tourist satisfaction degree could be of practical and instructive significances in the planning and management of wetland parks.

  13. Plan well, plan often

    Bill Block

    2013-01-01

    This issue includes an invited paper by Courtney Schultz and her colleagues commenting on the application of the newly adopted U.S. Forest Service Planning Rule (hereafter, the rule) for wildlife. The rule is basically implementing language to interpret the spirit and intent of the National Forest Management Act (NFMA) of 1976. Laws such as NFMA require additional...

  14. Language Planning: Corpus Planning.

    Baldauf, Richard B., Jr.

    1989-01-01

    Focuses on the historical and sociolinguistic studies that illuminate corpus planning processes. These processes are broken down and discussed under two categories: those related to the establishment of norms, referred to as codification, and those related to the extension of the linguistic functions of language, referred to as elaboration. (60…

  15. Isoeffect lines using TDF and CRE concepts

    Supe, S.J.; Sasane, J.B.; Gupta, M.K.; Supe, D.S.

    1979-01-01

    In most of the radiotherapy centres the treatment planning is based on isodose lines. Isoeffect lines are also being drawn based on the concepts of TDFs and CREs. A study has been made of whether the isoeffect lines based on the concepts of TDFs, CRes and the physical isodose lines are identical in all the treatment situations. Isoeffects lines for a few treatment schedules involving treatment of carcinoma of the bladder, treatment of cancer of the uterine cervix by combined intracavitary and external beam therapies and intracavitary therapy alone have been obtained and compared. The effect of treatment mode on the isoeffect lines has also been studied. It was found that the isodose curves and the isoeffect lines using the TDF and CRE concepts were not identical in all situations. Therefore, the ultimate treatment plans based on these isoeffect lines will not be exactly the same. The dependence of the isoeffect lines with the variation of the exponents of time and number of fractions used in the empirical relationship for NSD have also been investigated. Clinical trials have been initiated in the case of cancer of the bladder and cervix uterus based on the isodose curves and isoeffect lines using CRE and TDF concepts. (author)

  16. Quantum reading capacity

    Pirandola, Stefano; Braunstein, Samuel L; Lupo, Cosmo; Mancini, Stefano; Giovannetti, Vittorio

    2011-01-01

    The readout of a classical memory can be modelled as a problem of quantum channel discrimination, where a decoder retrieves information by distinguishing the different quantum channels encoded in each cell of the memory (Pirandola 2011 Phys. Rev. Lett. 106 090504). In the case of optical memories, such as CDs and DVDs, this discrimination involves lossy bosonic channels and can be remarkably boosted by the use of nonclassical light (quantum reading). Here we generalize these concepts by extending the model of memory from single-cell to multi-cell encoding. In general, information is stored in a block of cells by using a channel-codeword, i.e. a sequence of channels chosen according to a classical code. Correspondingly, the readout of data is realized by a process of ‘parallel’ channel discrimination, where the entire block of cells is probed simultaneously and decoded via an optimal collective measurement. In the limit of a large block we define the quantum reading capacity of the memory, quantifying the maximum number of readable bits per cell. This notion of capacity is nontrivial when we suitably constrain the physical resources of the decoder. For optical memories (encoding bosonic channels), such a constraint is energetic and corresponds to fixing the mean total number of photons per cell. In this case, we are able to prove a separation between the quantum reading capacity and the maximum information rate achievable by classical transmitters, i.e. arbitrary classical mixtures of coherent states. In fact, we can easily construct nonclassical transmitters that are able to outperform any classical transmitter, thus showing that the advantages of quantum reading persist in the optimal multi-cell scenario. (paper)

  17. Locational Prices in Capacity Subscription Market Considering Transmission Limitations

    S. Babaeinejad Sarookolaee

    2013-06-01

    Full Text Available This study focuses on one of the most effective type of capacity markets named Capacity Subscription (CS market which is predicted to be widely used in the upcoming smart grids. Despite variant researches done about the mechanism and structure of capacity markets, their performances have been rarely tested in the presence of network constraints. Considering this deficiency, we tried to propose a new method to determine capacity prices in the network considering the transmission line flow limitations named Local capacity Prices (LP. This method is quite new and has not been tried before in any other similar researches. The philosophy of the proposed method is to determine capacity prices considering each consumer share of total peak demand. The first advantage of LP is that the consumers who benefit from the transmission facilities and are the responsible for transmission congestions, pay higher capacity prices than those whom their needed electricity is prepared locally. The second advantage of LP is that consumers connected to the same bus do not have to pay same capacity price due to their different shares of total peak demand. For more clarification, two other different methods named Branches Flow limit as a Global Limit (BFGL and Locational Capacity Prices (LCP are proposed and compared to the LP method in order to show LP method efficiency. The numerical results obtained from case studies show that the LP method follows more justice market procedure which results in more efficient capacity prices in comparison to BFGL and LCP methods.

  18. 18 CFR 294.101 - Shortages of electric energy and capacity.

    2010-04-01

    ... customers; and (ii) It will report any modifications to its contingency plans for accommodating shortages... REGULATORY POLICIES ACT OF 1978 § 294.101 Shortages of electric energy and capacity. (a) Definition of... customers. (4) If a plan for accommodating any shortages of electric energy or capacity affecting its firm...

  19. Nuclear power as an option in electrical generation planning for Croatia

    Feretic, D.; Tomsic, Z.; Cavlina, N.; Kovacevic, T.

    2000-01-01

    The expected increase of electricity consumption in the next two decades, if covered mainly by domestic production, will require roughly 4500 MW of new installed capacity. The question is which resource mix would be optimal for the future power plants. Taking into account lack of domestic resources for electricity generation, current trends in the European energy markets, and environmental impact of various energy technologies, it seems reasonable for Croatia to keep the nuclear option open in the future energy planning. In line with that conclusion, this paper analyzes how the introduction of nuclear power plants would influence future power system expansion plans in Croatia, and the possibility to meet the Kyoto requirement. The effects of CO 2 emission tax and external costs on the optimal capacity mix and the emissions levels are also examined. (author)

  20. A Method of Flow-Shop Re-Scheduling Dealing with Variation of Productive Capacity

    Kenzo KURIHARA

    2005-02-01

    Full Text Available We can make optimum scheduling results using various methods that are proposed by many researchers. However, it is very difficult to process the works on time without delaying the schedule. There are two major causes that disturb the planned optimum schedules; they are (1the variation of productive capacity, and (2the variation of products' quantities themselves. In this paper, we deal with the former variation, or productive capacities, at flow-shop works. When production machines in a shop go out of order at flow-shops, we cannot continue to operate the productions and we have to stop the production line. To the contrary, we can continue to operate the shops even if some workers absent themselves. Of course, in this case, the production capacities become lower, because workers need to move from a machine to another to overcome the shortage of workers and some shops cannot be operated because of the worker shortage. We developed a new re-scheduling method based on Branch-and Bound method. We proposed an equation for calculating the lower bound for our Branch-and Bound method in a practical time. Some evaluation experiments are done using practical data of real flow-shop works. We compared our results with those of another simple scheduling method, and we confirmed the total production time of our result is shorter than that of another method by 4%.

  1. Uranium enrichment. Technology, economics, capacity

    Voigt, W.R. Jr.; Saire, D.E.; Gestson, D.K.; Peske, S.E.; Vanstrum, P.R.

    1983-01-01

    Large-scale enrichment of uranium has now been carried out for 40 years. While the gaseous diffusion process was the original choice of several countries and continues today to provide the major component of the world production of separative work, the last two decades have witnessed the development of a number of alternative processes for enrichment. These processes, which are being studied and deployed around the world, offer a wide range of technical and economic characteristics which will be useful in assuring adequate capacity to meet projected reactor fuel market needs through the rest of this century at competitive prices. With present uncertainties in future enriched uranium needs, it is apparent that flexibility in the deployment and operation of any enrichment process will be one of the prime considerations for the future. More economical production of separative work not only can have a beneficial impact on reactor fuel costs, but also tends to conserve natural uranium resources. This paper reviews the world scene in the enrichment component of the fuel cycle, including existing or planned commercial-scale facilities and announced R+D efforts on various processes. (author)

  2. Uranium enrichment: technology, economics, capacity

    Voigt, Jr., W. R.; Vanstrum, P. R.; Saire, D. E.; Gestson, D. K.; Peske, S. E.

    1982-08-01

    Large-scale enrichment of uranium has now been carried out for 40 years. While the gaseous diffusion process was the original choice of several countries and continues today to provide the major component of the world production of separative work, the last two decades have witnessed the development of a number of alternative processes for enrichment. These processes, which are being studied and deployed around the world, offer a wide range of technical and economic characteristics which will be useful in assuring adequate capacity to meet projected reactor fuel market needs through the rest of this century at competitive prices. With present uncertainties in future enriched uranium needs, it is apparent that flexibility in the deployment and operation of any enrichment process will be one of the prime considerations for the future. More economical production of separative work not only can have a beneficial impact on reactor fuel costs, but also tends to conserve natural uranium resources. This paper reviews the world scene in the enrichment component of the fuel cycle, including existing or planned commercial-scale facilities and announced R and D efforts on various processes.

  3. Uranium enrichment: technology, economics, capacity

    Voigt, W.R. Jr.; Vanstrum, P.R.; Saire, D.E.; Gestson, D.K.; Peske, S.E.

    1982-01-01

    Large-scale enrichment of uranium has now been carried out for 40 years. While the gaseous diffusion process was the original choice of several countries and continues today to provide the major component of the world production of separative work, the last two decades have witnessed the development of a number of alternative processes for enrichment. These processes, which are being studied and deployed around the world, offer a wide range of technical and economic characteristics which will be useful in assuring adequate capacity to meet projected reactor fuel market needs through the rest of this century at competitive prices. With present uncertainties in future enriched uranium needs, it is apparent that flexibility in the deployment and operation of any enrichment process will be one of the prime considerations for the future. More economical production of separative work not only can have a beneficial impact on reactor fuel costs, but also tends to conserve natural uranium resources. This paper reviews the world scene in the enrichment component of the fuel cycle, including existing or planned commercial-scale facilities and announced R and D efforts on various processes

  4. Deficiency of employability capacity

    Pelse I.

    2012-10-01

    Full Text Available Young unemployed people have comprised one of the significantly largest groups of the unemployed people in Latvia in recent years. One of the reasons why young people have difficulty integrating into the labour market is the “expectation gap” that exists in the relations between employers and the new generation of workers. Employers focus on capacity-building for employability such individual factors as strength, patience, self-discipline, self-reliance, self-motivation, etc., which having a nature of habit and are developed in a long-term work socialization process, which begins even before the formal education and will continue throughout the life cycle. However, when the socialization is lost, these habits are depreciated faster than they can be restored. Currently a new generation is entering the labour market, which is missing the succession of work socialization. Factors, such as rising unemployment and poverty in the background over the past twenty years in Latvia have created a very unfavourable employability background of “personal circumstances” and “external factors”, which seriously have impaired formation of the skills and attitudes in a real work environment. The study reveals another paradox – the paradox of poverty. Common sense would want to argue that poverty can be overcome by the job. However, the real state of affairs shows that unfavourable coincidence of the individual, personal circumstances and external factors leads to deficit of employability capacity and possibility of marked social and employment deprivation.

  5. New overhead lines are required for the land - and Europe. The new regulation of the TEN-E regulations and their consequences for the Germann planning law and licensing law for high-voltage power lines under special consideration of the regulations of the public relations; Neue Leitungen braucht das Land - und Europa. Die Neuregelung der TEN-E-Leitlinien und deren Konsequenzen fuer das deutsche Planungs- und Genehmigungsrecht fuer Hoechstspannungsleitungen unter besonderer Beruecksichtigung der Vorschriften ueber die Oeffentlichkeitsbeteiligung

    Schadtle, Kai [Stuttgart Univ. (Germany). Abt. fuer Rechtswissenschaft

    2013-05-15

    The German energy policy turnaround requires an optimization of the energy infrastructure. The energy policy objectives of the European Union with respect to competitiveness, security of supply and sustainability require a rapid expansion and transformation of the European energy infrastructure. Under this aspect, the author of the contribution under consideration reports on the revision of the TEN-E guidelines and their consequences for the German planning law and licensing law for high-voltage power lines with special consideration of the rules of the public relations. The national legal framework for the development of the German transmission system and the design of the new TEN-E guidelines for the trans-European network development are presented.

  6. 75 FR 51831 - Request for Measures of Health Plan Efforts To Address Health Plan Members' Health Literacy Needs

    2010-08-23

    ... and health plans. The results of the planned survey may become an important source of information for... services and nurse advice lines, the quality and accessibility of health plan information on coverage...

  7. Transmission investment and planning in deregulated market environment : a literature survey (part 1)

    Wen, F.; Wu, F.F.

    2005-01-01

    This paper is the first half of a 2-part paper that provided details of a comprehensive survey of issues related to transmission investment and expansion planning in the electricity market. The lack of adequate transmission capacity has played an important role in recent power crises, and deregulation has had a significant impact on the investment and planning process of transmission systems. The main objective of transmission investment is to meet load demands as cheaply as possible. In a deregulated market, there is no longer centrally coordinated planning of new generation. Transmission planning is generally not coordinated with generation planning. There is considerable uncertainty with regard to transmission capacity requirements due to long lead times for transmission construction. Generating plants and transmission lines are built according to investor assessments and private interests, and current transmission systems were not designed to handle supply and demand patterns in competitive markets. It was recommended that new transmission plans should meet reliability requirements while minimizing expected unserved energy. It was concluded that reliability criteria must be redefined to account for the fact that transmission systems are more stressed under deregulation. Two popular financial transmission rights were also discussed, notably (1) point-to-point financial transmission rights (FTR); and (2) financial flowgate rights (FGR)

  8. Assessing institutional capacities to adapt to climate change - integrating psychological dimensions in the Adaptive Capacity Wheel

    Grothmann, T.; Grecksch, K.; Winges, M.; Siebenhüner, B.

    2013-03-01

    Several case studies show that "soft social factors" (e.g. institutions, perceptions, social capital) strongly affect social capacities to adapt to climate change. Many soft social factors can probably be changed faster than "hard social factors" (e.g. economic and technological development) and are therefore particularly important for building social capacities. However, there are almost no methodologies for the systematic assessment of soft social factors. Gupta et al. (2010) have developed the Adaptive Capacity Wheel (ACW) for assessing the adaptive capacity of institutions. The ACW differentiates 22 criteria to assess six dimensions: variety, learning capacity, room for autonomous change, leadership, availability of resources, fair governance. To include important psychological factors we extended the ACW by two dimensions: "adaptation motivation" refers to actors' motivation to realise, support and/or promote adaptation to climate. "Adaptation belief" refers to actors' perceptions of realisability and effectiveness of adaptation measures. We applied the extended ACW to assess adaptive capacities of four sectors - water management, flood/coastal protection, civil protection and regional planning - in North Western Germany. The assessments of adaptation motivation and belief provided a clear added value. The results also revealed some methodological problems in applying the ACW (e.g. overlap of dimensions), for which we propose methodological solutions.

  9. Assessing institutional capacities to adapt to climate change: integrating psychological dimensions in the Adaptive Capacity Wheel

    Grothmann, T.; Grecksch, K.; Winges, M.; Siebenhüner, B.

    2013-12-01

    Several case studies show that social factors like institutions, perceptions and social capital strongly affect social capacities to adapt to climate change. Together with economic and technological development they are important for building social capacities. However, there are almost no methodologies for the systematic assessment of social factors. After reviewing existing methodologies we identify the Adaptive Capacity Wheel (ACW) by Gupta et al. (2010), developed for assessing the adaptive capacity of institutions, as the most comprehensive and operationalised framework to assess social factors. The ACW differentiates 22 criteria to assess 6 dimensions: variety, learning capacity, room for autonomous change, leadership, availability of resources, fair governance. To include important psychological factors we extended the ACW by two dimensions: "adaptation motivation" refers to actors' motivation to realise, support and/or promote adaptation to climate; "adaptation belief" refers to actors' perceptions of realisability and effectiveness of adaptation measures. We applied the extended ACW to assess adaptive capacities of four sectors - water management, flood/coastal protection, civil protection and regional planning - in northwestern Germany. The assessments of adaptation motivation and belief provided a clear added value. The results also revealed some methodological problems in applying the ACW (e.g. overlap of dimensions), for which we propose methodological solutions.

  10. THE BUFFER CAPACITY OF AIRWAY EPITHELIAL SECRETIONS

    Dusik eKim

    2014-06-01

    Full Text Available The pH of airway epithelial secretions influences bacterial killing and mucus properties and is reduced by acidic pollutants, gastric reflux, and respiratory diseases such as cystic fibrosis (CF. The effect of acute acid loads depends on buffer capacity, however the buffering of airway secretions has not been well characterized. In this work we develop a method for titrating micro-scale (30 µl volumes and use it to study fluid secreted by the human airway epithelial cell line Calu-3, a widely used model for submucosal gland serous cells. Microtitration curves revealed that HCO3- is the major buffer. Peak buffer capacity (β increased from 17 to 28 mM/pH during forskolin stimulation, and was reduced by >50% in fluid secreted by cystic fibrosis transmembrane conductance regulator (CFTR-deficient Calu-3 monolayers, confirming an important role of CFTR in HCO3- secretion. Back-titration with NaOH revealed non-volatile buffer capacity due to proteins synthesized and released by the epithelial cells. Lysozyme and mucin concentrations were too low to buffer Calu-3 fluid significantly, however model titrations of porcine gastric mucins at concentrations near the sol-gel transition suggest that mucins may contribute to the buffer capacity of ASL in vivo. We conclude that CFTR-dependent HCO3- secretion and epithelially-derived proteins are the predominant buffers in Calu-3 secretions.

  11. Research for the Influence of Distribution Network Line Reclosing Current on Line Protection

    Yu Kansheng

    2016-01-01

    Full Text Available According to the distribution network line structure and reclosing control strategy, the system simulation model of distribution network lines has established based on the real-time digital simulation RTDS. Based on this, distribution network switching impulse current characteristic has researched with different capacity, different distribution and different load power factor under the different voltage switching angles. The results of the study provide a scientific basis for distribution network line protection setting, in order to further lay the foundation for improvement the validity and reliability of distribution network line protection action.

  12. Wind energy planning in Denmark

    Godtfredsen, F.; Lemming, J.; Nielsen, S.R.; Jessien, S.

    1992-01-01

    The total capacity of the about 3300 Danish wind turbines is approximately 450 MW. Most of the wind turbines have been erected detached or in small clusters by private citizens - especially by joint ownership. 100 MW of the capacity have been installed by the power companies, mainly in wind farms. Up till now the privately owned wind turbines have been erected without a previous planning process. Increased expansion of wind energy makes demands on physical planning, since access to suitable locations in Denmark is limited. Hence more coordination is called for between the interested parties to ensure optimal utilization of the sites allocated by the physical planning authorities. A siting committee appointed by the Government has recommended locations for additional 100 MW power company wind farms as well as a more detailed planning in each local community. The detailed planning in the municipality of Thisted is described. (au)

  13. Primer on gas integrated resource planning

    Goldman, C.; Comnes, G.A.; Busch, J.; Wiel, S. [Lawrence Berkeley Lab., CA (United States)

    1993-12-01

    This report discusses the following topics: gas resource planning: need for IRP; gas integrated resource planning: methods and models; supply and capacity planning for gas utilities; methods for estimating gas avoided costs; economic analysis of gas utility DSM programs: benefit-cost tests; gas DSM technologies and programs; end-use fuel substitution; and financial aspects of gas demand-side management programs.

  14. Dealing with Uncertainty in Operational Transport Planning

    Zutt, J.; Van Gemund, A.J.C.; De Weerdt, M.M.; Witteveen, C.

    2010-01-01

    An important problem in transportation is how to ensure efficient operational route planning when several vehicles share a common road infrastructure with limited capacity. Examples of such a problem are route planning for automated guided vehicles in a terminal and route planning for aircraft

  15. Managing Plan Implementation in the Asante Akyem South District ...

    Managing Plan Implementation in the Asante Akyem South District Assembly: Capacity Issues and Challenges. ... This paper uses a case study approach to appraise the capacity of the Asante Akyem South District Assembly (AASDA) in ...

  16. 1990s: High Capacity Backbones

    First page Back Continue Last page Overview Graphics. 1990s: High Capacity Backbones. Backbone capacities increased from 2.5 Gb/s to 100s of Gb/s during the 1990's. Wavelength division multiplexing with 160 waves of 10 Gb/s was commercially available. Several high-capacity backbones built in the US and Europe.

  17. Competitive Capacity Investment under Uncertainty

    X. Li (Xishu); R.A. Zuidwijk (Rob); M.B.M. de Koster (René); R. Dekker (Rommert)

    2016-01-01

    textabstractWe consider a long-term capacity investment problem in a competitive market under demand uncertainty. Two firms move sequentially in the competition and a firm’s capacity decision interacts with the other firm’s current and future capacity. Throughout the investment race, a firm can

  18. Integrated capacity and inventory decisions

    Dellaert, N.P.; Flapper, S.D.P.; Tan, T.; Jeunet, J.; Klatte, D.; Lüthi, H.-J.; Schmedders, K.

    2012-01-01

    This paper deals with the simultaneous acquisition of capacity and material in a situation with uncertain demand, with non-zero lead-times for the supply of both material and capacity. Although there is a lot of literature on the time-phased acquisition of capacity and material, most of this

  19. Landfill Construction and Capacity Expansion

    Andre, F.J.; Cerda, E.

    2003-01-01

    We study the optimal capacity and lifetime of landfills taking into account their sequential nature.Such an optimal capacity is characterized by the so-called Optimal Capacity Condition.Particular versions of this condition are obtained for two alternative settings: first, if all the landfills are

  20. Capacity expansion model of wind power generation based on ELCC

    Yuan, Bo; Zong, Jin; Wu, Shengyu

    2018-02-01

    Capacity expansion is an indispensable prerequisite for power system planning and construction. A reasonable, efficient and accurate capacity expansion model (CEM) is crucial to power system planning. In most current CEMs, the capacity of wind power generation is considered as boundary conditions instead of decision variables, which may lead to curtailment or over construction of flexible resource, especially at a high renewable energy penetration scenario. This paper proposed a wind power generation capacity value(CV) calculation method based on effective load-carrying capability, and a CEM that co-optimizes wind power generation and conventional power sources. Wind power generation is considered as decision variable in this model, and the model can accurately reflect the uncertainty nature of wind power.

  1. Study on Tourist Carrying Capacity Based on Matter Element Analysis

    LiuYunguo; FanTing; LiXin; ZhouMing; WangXianhai

    2005-01-01

    This paper proposes that it is necessary to implement the concept of tourist carrying capacity to facilitate the tourism planning, and presents a method to evaluate the carrying capacity. The method called matter element analysis can solve the uncertain and incompatible problem of the evaluated factors in assessing carrying capacity.The current state of a destination's carrying capacity can be determined by establishing the standard indexes and the matter element model. Through the evaluating of the travel industry zones of the Autonomous Prefecture of Western Hunan, the method is proved to be simple and feasible, and it is improved to be significant for the tourism planning and determination as well as the sustainable development of the regional tourism.

  2. Does Assisted Living Capacity Influence Case Mix at Nursing Homes?

    Clement, Jan P; Khushalani, Jaya

    2015-01-01

    Assisted living facilities (ALFs) have grown over the past few decades. If they attract residents with lower care needs away from nursing homes (NHs), NHs may be left with higher case mix residents. We study the relationship between ALF bed market capacity and NH case mix in a state (Virginia) where ALF bed capacity stabilized after a period of growth. Similarly, NH capacity and use had been stable. While it is interesting to study markets in flux, for planning purposes, it is also important to examine what happens after periods of turbulence and adaptation. Our findings show some substitution of ALF for NH care, but the relationship is not linear with ALF market capacity. Communities need to consider the interplay of ALFs and NHs in planning for long-term care services and supports. Policies supporting ALFs may enable care needs to be met in a lower cost setting than the NH.

  3. Does Assisted Living Capacity Influence Case Mix at Nursing Homes?

    Jan P. Clement PhD

    2015-05-01

    Full Text Available Assisted living facilities (ALFs have grown over the past few decades. If they attract residents with lower care needs away from nursing homes (NHs, NHs may be left with higher case mix residents. We study the relationship between ALF bed market capacity and NH case mix in a state (Virginia where ALF bed capacity stabilized after a period of growth. Similarly, NH capacity and use had been stable. While it is interesting to study markets in flux, for planning purposes, it is also important to examine what happens after periods of turbulence and adaptation. Our findings show some substitution of ALF for NH care, but the relationship is not linear with ALF market capacity. Communities need to consider the interplay of ALFs and NHs in planning for long-term care services and supports. Policies supporting ALFs may enable care needs to be met in a lower cost setting than the NH.

  4. Capacity Ten-Seven

    NONE

    2006-05-04

    The study was initiated to assemble UK solar experts who would define the parameters for the design of solar cell process plant with a capacity of about 10MWp per annum and establish the optimum substrate size, cell configuration and junction structure and show that these characteristics are suited to high volume low cost production. The study focused on proven materials and techniques rather than on innovative materials and processes. Peak production should deliver panels at a cost of less than $1 per peak watt. The study was reported under the headings of fundamental studies, front contact deposition, semiconductor deposition, rear contact deposition, cell isolation and initial design study. Since much of the work is commercially sensitive, not all findings are divulged in the report. The work, which achieved all its targets, was carried out by ICP Solar Technologies UK Ltd under contract to the DTI.

  5. Assessing Capacity for Sustainability of Effective Programs and Policies in Local Health Departments.

    Tabak, Rachel G; Duggan, Katie; Smith, Carson; Aisaka, Kristelle; Moreland-Russell, Sarah; Brownson, Ross C

    2016-01-01

    Sustainability has been defined as the existence of structures and processes that allow a program to leverage resources to effectively implement and maintain evidence-based public health and is important in local health departments (LHDs) to retain the benefits of effective programs. Explore the applicability of the Program Sustainability Framework in high- and low-capacity LHDs as defined by national performance standards. Case study interviews from June to July 2013. Standard qualitative methodology was used to code transcripts; codes were developed inductively and deductively. Six geographically diverse LHD's (selected from 3 of high and 3 of low capacity) : 35 LHD practitioners. Thematic reports explored the 8 domains (Organizational Capacity, Program Adaptation, Program Evaluation, Communications, Strategic Planning, Funding Stability, Environmental Support, and Partnerships) of the Program Sustainability Framework. High-capacity LHDs described having environmental support, while low-capacity LHDs reported this was lacking. Both high- and low-capacity LHDs described limited funding; however, high-capacity LHDs reported greater funding flexibility. Partnerships were important to high- and low-capacity LHDs, and both described building partnerships to sustain programming. Regarding organizational capacity, high-capacity LHDs reported better access to and support for adequate staff and staff training when compared with low-capacity LHDs. While high-capacity LHDs described integration of program evaluation into implementation and sustainability, low-capacity LHDs reported limited capacity for measurement specifically and evaluation generally. When high-capacity LHDs described program adoption, they discussed an opportunity to adapt and evaluate. Low-capacity LHDs struggled with programs requiring adaptation. High-capacity LHDs described higher quality communication than low-capacity LHDs. High- and low-capacity LHDs described strategic planning, but high-capacity

  6. Immunomodulating capacity of kefir.

    Vinderola, Celso G; Duarte, Jairo; Thangavel, Deepa; Perdigón, Gabriela; Farnworth, Edward; Matar, Chantal

    2005-05-01

    Kefir is a fermented milk produced by the action of lactic acid bacteria, yeasts and acetic acid bacteria, trapped in a complex matrix of polysaccharides and proteins. Beyond its inherent high nutritional value as a source of proteins and calcium, kefir has a long tradition of being regarded as good for health in countries where it is a staple in the diet. However, published human or animal feeding trials to substantiate this view are not numerous. The aim of this work was to determine the immunomodulating capacity of kefir on the intestinal mucosal immune response in mice and to demonstrate the importance of dose and cell viability on this response. BALB/c mice were fed with commercial kefir ad libitum (diluted 1/10, 1/50, 1/100 or 1/200) or pasteurized kefir (diluted 1/6, 1/10, 1/50, 1/100) for 2, 5 or 7 consecutive days. At the end of each feeding period, the bacterial translocation assay was performed in the liver. Small intestine structure was studied by haematoxilin-eosin staining and light microscopy. The number of IgA+ and IgG+ cells was also determined. For the functional doses chosen, cytokines (IL-2, IL-4, IL-6, IL-10, IL-12, TNF-alpha and IFN-gamma) were determined. Kefir and pasteurized kefir were able to modulate the mucosal immune system in a dose-dependent manner. Kefir was administred 10-times more diluted than pasteurized kefir, but it induced an immunomodulation of similar magnitude, indicating the importance of cell viabilty. The results suggest that a Th1 response was controlled by Th2 cytokines induced by kefir feeding. Pasteurized kefir would induce both Th2 and Th1 responses. This is the first study in vivo regarding the mechanisms involved in the immunomodulating capacity of the oral administration of kefir containing viable or heat-inactivated bacteria at different doses.

  7. Power system capacity expansion planning model considering carbon emissions constraints

    Diego Adolfo Mejía Giraldo

    2012-01-01

    Full Text Available Este artículo presenta un modelo de planeamiento de expansión de la capacidad de sistemas de potencia considerando restricciones en emisiones de carbono. Además de los aspectos técnicos y económicos considerados usualmente en el proceso de planeamiento, se consideran dos políticas ambientales que consisten en el cobro de un impuesto y un límite anual a las emisiones de dióxido de carbono (CO2. Adicionalmente se ha incluido el retiro gradual de las plantas de generación ineficientes. Este abordaje garantiza una producción de electricidad más limpia en el sistema expandido a un costo relativamente bajo. El modelo propuesto considera la red de transmisión y es aplicado a un sistema de potencia de prueba de 4 regiones y a uno de 11 regiones para un horizonte de planeación de 20 años. Los resultados muestran decisiones de inversión prácticas en términos de sostenibilidad y costos.

  8. Modeling and forecasting of electrical power demands for capacity planning

    Al-Shobaki, S.; Mohsen, M.

    2007-01-01

    Jordan imports oil from neighboring countries for use in power production. As such, the cost of electricity production is high compared to oil producing countries. It is anticipated that Jordan will face major challenges in trying to meet the growing energy and electricity demands while also developing the energy sector in a way that reduces any adverse impacts on the economy, the environment and social life. This paper described the development of forecasting models to predict future generation and sales loads of electrical power in Jordan. Two models that could be used for the prediction of electrical energy demand in Amman, Jordan were developed and validated. An analysis of the data was also presented. The first model was based on the levels of energy generated by the National Electric Power Company (NEPCO) and the other was based on the levels of energy sold by the company in the same area. The models were compared and the percent error was presented. Energy demand was also forecasted across the next 60 months for both models. Results were then compared with the output of the in-house forecast model used by NEPCO to predict the levels of generated energy needed across the 60 months time period. It was concluded that the NEPCO model predicted energy demand higher than the validated generated data model by an average of 5.25 per cent. 8 refs., 5 tabs., 15 figs

  9. Modeling and forecasting of electrical power demands for capacity planning

    Al-Shobaki, S. [Hashemite Univ., Zarka (Jordan). Dept. of Industrial Engineering; Mohsen, M. [Hashemite Univ., Zarka (Jordan). Dept. of Mechanical Engineering

    2007-07-01

    Jordan imports oil from neighboring countries for use in power production. As such, the cost of electricity production is high compared to oil producing countries. It is anticipated that Jordan will face major challenges in trying to meet the growing energy and electricity demands while also developing the energy sector in a way that reduces any adverse impacts on the economy, the environment and social life. This paper described the development of forecasting models to predict future generation and sales loads of electrical power in Jordan. Two models that could be used for the prediction of electrical energy demand in Amman, Jordan were developed and validated. An analysis of the data was also presented. The first model was based on the levels of energy generated by the National Electric Power Company (NEPCO) and the other was based on the levels of energy sold by the company in the same area. The models were compared and the percent error was presented. Energy demand was also forecasted across the next 60 months for both models. Results were then compared with the output of the in-house forecast model used by NEPCO to predict the levels of generated energy needed across the 60 months time period. It was concluded that the NEPCO model predicted energy demand higher than the validated generated data model by an average of 5.25 per cent. 8 refs., 5 tabs., 15 figs.

  10. Business intelligence and capacity planning: web-based solutions.

    James, Roger

    2010-07-01

    Income (activity) and expenditure (costs) form the basis of a modern hospital's 'business intelligence'. However, clinical engagement in business intelligence is patchy. This article describes the principles of business intelligence and outlines some recent developments using web-based applications.

  11. Rough-Cut Capacity Planning in Multimodal Freight Transportation Networks

    2012-09-30

    metaheuristics. Parti- cle Swarm Optimization, Ant Colony Optimization, and Artificial Bee Colony Algo- rithms are newer examples of some biologically... nest for a food source. Each ant, as it travels leaves a pheromone trail which is detected by subsequent ants. Initially, ants randomly choose a...trail on shorter paths connecting the nest and the food source tends to be stronger. Eventually, all ants will choose to follow the path containing the

  12. Uranium enrichment plans and policies

    Schwennesen, J.L.

    1981-01-01

    Significant progress has been made in US efforts to expand its enrichment capacity. The Cascade Improvement Program (CIP) and Cascade Upgrading Program (CUP) are now complete at Oak Ridge and Paducah and almost complete at Portsmouth. Considerable progress has also been made in constructing the Gas Centrifuge Enrichment Plant (GCEP), and physical construction of the first process building is well under way. Current plans are to have two process buildings on-line by 1989 with the remaining six buildings to be added sequentially as needed to meet demand. The status of DOE enrichment services contracts is essentially unchanged from that reported at last year's seminar. The OUEA latest forecast of nuclear power growth, however, is considerably lower than reported last year, although a leveling trend is becoming apparent. The Variable Tails Assay Option (VTAO) of the AFC contract was made available for the third time for FY 1983. The DOE inventories of natural uranium still remain high. The Department of Energy will dispose of this material by using it for Government programs and for enrichment plant operations. It appears that Government inventories of uranium are adequate through at least the mid-1990s. It remains DOE policy not to dispose of its natural uranium stocks through direct sales in the marketplace, except for very small quantities or if an emergency situation would exist and all reasonable attempts had been made, without success, to obtain natural uranium from commercial sources. Finally, with regard to DOE plans on future transaction tails assays, it still appears likely that the current 0.20 percent uranium-235 reference tails assay will be maintained until well into the 1990s, at which time it might be increased up to 0.25 percent uranium-235

  13. What factors influence mitigative capacity?

    Winkler, Harald; Baumert, Kevin; Blanchard, Odile; Burch, Sarah; Robinson, John

    2007-01-01

    This article builds on Yohe's seminal piece on mitigative capacity, which elaborates 'determinants' of mitigative capacity, also reflected in the IPCC's third assessment report. We propose a revised definition, where mitigative capacity is a country's ability to reduce anthropogenic greenhouse gas emissions or enhance natural sinks. By 'ability' we mean skills, competencies, fitness, and proficiencies that a country has attained which can contribute to GHG emissions mitigation. A conceptual framework is proposed, linking mitigative capacity to a country's sustainable development path, and grouping the factors influencing mitigative capacity into three main sets: economic factors, institutional ones, and technology. Both quantitative and qualitative analysis of factors is presented, showing how these factors vary across countries. We suggest that it is the interplay between the three economic factors-income, abatement cost and opportunity cost-that shape mitigative capacity. We find that income is an important economic factor influencing mitigative capacity, while abatement cost is important in turning mitigative capacity into actual mitigation. Technology is a critical mitigative capacity, including the ability to absorb existing climate-friendly technologies or to develop innovative ones. Institutional factors that promote mitigative capacity include the effectiveness of government regulation, clear market rules, a skilled work force and public awareness. We briefly investigate such as high abatement cost or lack of political willingness that prevent mitigative capacity from being translated into mitigation

  14. Radio-capacity of ecosystems

    Kultakhmedov, Yu.; Kultakhmedova-Vyshnyakova, V.

    1997-01-01

    This paper consider a universal approach to ecosystems of different types, based on representation of their radio-capacity. The concept of ecosystem includes reproduction of components (bio-productivity) and conditions such as maintaining of environment quality. Radio-capacity in the case of radionuclide pollution appears in accumulation and redistribution of radionuclides in the ecosystem. As a result the radionuclides are redistributed and buried in soil or lake bottom sediments. Estimation models for the radio-capacity of water and terrestrial ecosystems are represented. The calculations of the radio-capacity factor of water ecosystems are performed, and the high radio-capacity of a freshwater reservoir (F=0.6-0.8) and extremely high radio-capacity of a reservoir cascade (F c =0.99) is shown material from the Dnieper's cascade reservoirs. The methods of radio-capacity estimation of agroecosystems, wood and marine ecosystems are developed. (authors)

  15. Prestressed Concrete-Lined Pressure Tunnels : Towards Improved Safety and Economical Design

    Simanjuntak, Y.

    2015-01-01

    Pressure tunnels for hydropower plants are relatively expensive constructions, particularly when steel linings are used. Concrete linings can be economically attractive; however, their applicability is limited by the low tensile strength of concrete. Techniques to improve the bearing capacity of

  16. Development of cross-border transmission lines in Poland and their significance for the Central East Europeam energy market

    Andruszkiewicz, Jerzy

    2010-09-15

    This publication presents the existing cross-border transmission lines connecting Poland with neighbouring countries and their use in the currently applied mechanisms for making available the transfer capacities. The prospects and the considered options of development in cross-border interconnections were presented, taking into account their role in the integration of the European market and of the trade relations with neighbouring counties other than members of the European Community. The role of the planned interconnections in solving the problems of central European countries connected with the implementation of European strategy that reduce CO2 emissions in the area of electricity generation was discussed.

  17. Strengthening Africa's capacity to design and implement strategies for food and nutrition security

    Babu, Suresh Chandra; Rhoe, Valerie; Temu, Andrew; Hendriks, Sheryl

    2004-01-01

    "Among the capacity-strengthening challenges the region faces are inadequate in-country capacity, institutional weaknesses, lack of multidisciplinary approaches to problem solving, expatriates' limited incountry experience, poor governance, and failure to monitor the sustainability of development efforts and to plan for future capacity generation....The current gaps in capacity are known, but as political, environmental, technical, and social contexts change, new needs will arise. Therefore, ...

  18. Methodologies for estimating one-time hazardous waste generation for capacity generation for capacity assurance planning

    Tonn, B.; Hwang, Ho-Ling; Elliot, S.; Peretz, J.; Bohm, R.; Hendrucko, B.

    1994-04-01

    This report contains descriptions of methodologies to be used to estimate the one-time generation of hazardous waste associated with five different types of remediation programs: Superfund sites, RCRA Corrective Actions, Federal Facilities, Underground Storage Tanks, and State and Private Programs. Estimates of the amount of hazardous wastes generated from these sources to be shipped off-site to commercial hazardous waste treatment and disposal facilities will be made on a state by state basis for the years 1993, 1999, and 2013. In most cases, estimates will be made for the intervening years, also

  19. Scenarios of Expansion to Electric Generation Capacity

    José Somoza-Cabrera

    2017-06-01

    Full Text Available We show the building scenarios of expansion to electric generation capacity enough to supply the demand to 2050. We were using the LEAP facility (Long-range Energy Alternatives Planning System, to simulate dispatch of electricity at minimum cost. Finally, we show the cost-benefice analysis of the technologies availability, included externality and CO2 emission limited. However that we included the externals cost in this analysis, it results insufficient to closed gap between fossil and renewable technologies of electric generation. Nevertheless, in some opportunities the renewable options had very important participations in the minimal cost scenario of expansion.

  20. Reaching consensus: a review on sexual health training modules for professional capacity building

    Zahra Karimian

    2018-01-01

    Full Text Available Background: Professional capacity building (PCB is the focus point in health-related subjects.The present study was conducted to systematically review the existing sexual health training modules for health care providers.Methods: The following keywords were used to search: training, education, professional capacity, practitioner, sexual health, skill education, module, course, package and curriculum.The term MESH is referred to Medical Subject Headings and the following databases were investigated: MEDLINE, EMBASE, PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL, The Cochrane Library and Web of Science, Scopus, Google Scholar, SID,Magiran, and Iranmedex. All articles from 1980 to 2015 were extracted. Online modules were excluded. Considering that lesson plan was the basis of instruction, the modules were selected based on the characteristics of the lesson plans.Results: A total number of 38 published training modules in the field of sexuality we redetermined. In total, more than half of the modules (58% were designed for medical doctor sand allied health professionals and the remaining (42% were for nurses and midwives. Almost all the modules (97% were introduced and utilized in developed countries, and only 3% were disseminated in developing countries.Conclusion: There are invaluable modules to build professional capacity in the field of sexual health. As a number of modules have been designed for nurses and midwifes, as the first-line health care providers, the use of these groups in sexual counseling and empowerment for sexual health is essential. No sexual health training program was designed in Iran. Therefore, designing such modules according to Iranian culture is strongly recommended.

  1. Reaching consensus: a review on sexual health training modules for professional capacity building.

    Karimian, Zahra; Azin, Seied Ali; Javid, Nasrin; Araban, Marzieh; Maasoumi, Raziyeh; Aghayan, Shahrokh; Merghati Khoie, Effat

    2018-01-01

    Background: Professional capacity building (PCB) is the focus point in health-related subjects.The present study was conducted to systematically review the existing sexual health training modules for health care providers. Methods: The following keywords were used to search: training, education, professional capacity, practitioner, sexual health, skill education, module, course, package and curriculum.The term MESH is referred to Medical Subject Headings and the following databases were investigated: MEDLINE, EMBASE, PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), The Cochrane Library and Web of Science, Scopus, Google Scholar, SID,Magiran, and Iranmedex. All articles from 1980 to 2015 were extracted. Online modules were excluded. Considering that lesson plan was the basis of instruction, the modules were selected based on the characteristics of the lesson plans. Results: A total number of 38 published training modules in the field of sexuality we redetermined. In total, more than half of the modules (58%) were designed for medical doctor sand allied health professionals and the remaining (42%) were for nurses and midwives. Almost all the modules (97%) were introduced and utilized in developed countries, and only 3% were disseminated in developing countries. Conclusion: There are invaluable modules to build professional capacity in the field of sexual health. As a number of modules have been designed for nurses and midwifes, as the first-line health care providers, the use of these groups in sexual counseling and empowerment for sexual health is essential. No sexual health training program was designed in Iran. Therefore, designing such modules according to Iranian culture is strongly recommended.

  2. VT Boundaries - all lines

    Vermont Center for Geographic Information — (Link to Metadata) The BNDHASH dataset depicts Vermont villages, towns, counties, Regional Planning Commissions (RPC), and LEPC (Local Emergency Planning Committee)...

  3. Cable line engineering

    Jang, Hak Sin; Kim, Sin Yeong

    1998-02-01

    This book is about cable line engineering. It is comprised of nine chapters, which deals with summary of cable communication such as way, process of cable communication and optical communication, Line constant of transmission on primary constant, reflection and crosstalk, communication cable line of types like flat cable, coaxial cable and loaded cable, Install of communication line with types and facility of aerial line, construction method of communication line facility, Measurement of communication line, Carrier communication of summary, PCM communication with Introduction, regeneration relay system sampling and quantization and Electric communication service and general information network with mobile communication technique and satellite communication system.

  4. Capacity Credit and Security of Supply

    Chozas, Julia Fernandez; Mathiesen, Brian Vad

    2015-01-01

    electricity systems are planned, and how renewable energies fit in these systems. The second part of the article assesses the actual contribution that variable renewable energies can make to security of supply, firstly from a qualitative point of view and secondly in measurable terms. The study is based......This paper addresses the question of how renewable energies can contribute to security of supply. In order to analyse this subject, the paper has two differentiated parts. In the first part, the concept of security of supply is reviewed. This provides the baseline to understand how current...... demand for electricity is highest, the study focuses on the capacity credit of future Danish scenarios including high penetrations of offshore wind, onshore wind, wave and solar PV. The results of this project can ultimately lead towards the improvement of existing rules and methods in system planning...

  5. Digital Model of Railway Electric Traction Lines

    Garg, Rachana; Mahajan, Priya; Kumar, Parmod

    2017-08-01

    The characteristic impedance and propagation constant define the behavior of signal propagation over the transmission lines. The digital model for railway traction lines which includes railway tracks is developed, using curve fitting technique in MATLAB. The sensitivity of this model has been computed with respect to frequency. The digital sensitivity values are compared with the values of analog sensitivity. The developed model is useful for digital protection, integrated operation, control and planning of the system.

  6. Rotation capacity of self-compacting steel fiber reinforced concrete

    Schumacher, P.

    2006-01-01

    Steel fiber reinforced concrete (SFRC) has been used in segmental tunnel linings in the past years. In order to investigate the effect of steel fibers on the rotation capacity of plastic hinges in self-compacting concrete (SCC) the effect of the addition of fibers to SCC in compression, tension and

  7. Capacity competition in electricity markets

    Crampes, Claude; Creti, Anna

    2005-01-01

    The article analyzed a two-stage game where capacity constrained electricity generators first choose how much capacity they make available and then compete in a uniform-rice auction. It is studied how capacity withholding can be used strategically to enforce market power and how uniform auctions in the price game change the results of capacity constrained competition models. The uniform auction procedure gives strong incentives to capacity restriction. At equilibrium, however, power shortage never occurs. Though auctions in electricity markets have already been studied by several economists, yet an important feature of spot trading is the capacity availability decision. In fact, for technical reasons, such as equipment maintenance or failures, the installed capacity may not work at maximum operating level and the spot market rules oblige generators to announce which plants they are willing to use and simultaneously their offer prices. Beside technical reasons, the so-called 'capacity declarations' also offer a strategic instrument for firms: by restricting capacity, operators can benefit from scarcity rents. Assessing whether generators withhold capacity is an intriguing issue for real electricity markets, though proving it is a difficult task. Several theoretical papers show that generators are able to keep wholesale prices high as compared to their generation costs. In our model, a generator is not obliged to declare all installed capacity as available, but decides on the amount of MW of electricity that is available. Hence the available capacity is an endogenous variable while the installed one is exogenous. The distinction between installed capacities and 'available' capacities allows to explain clearly whether generators exert market power by declaring unavailable some production units. Although we find multiple sub game perfect equilibria that cannot be eliminated by Pareto-dominance, all the outcomes are characterized by market price at the highest

  8. Algorithmic complexity of quantum capacity

    Oskouei, Samad Khabbazi; Mancini, Stefano

    2018-04-01

    We analyze the notion of quantum capacity from the perspective of algorithmic (descriptive) complexity. To this end, we resort to the concept of semi-computability in order to describe quantum states and quantum channel maps. We introduce algorithmic entropies (like algorithmic quantum coherent information) and derive relevant properties for them. Then we show that quantum capacity based on semi-computable concept equals the entropy rate of algorithmic coherent information, which in turn equals the standard quantum capacity. Thanks to this, we finally prove that the quantum capacity, for a given semi-computable channel, is limit computable.

  9. Dementia, Decision Making, and Capacity.

    Darby, R Ryan; Dickerson, Bradford C

    After participating in this activity, learners should be better able to:• Assess the neuropsychological literature on decision making and the medical and legal assessment of capacity in patients with dementia• Identify the limitations of integrating findings from decision-making research into capacity assessments for patients with dementia ABSTRACT: Medical and legal professionals face the challenge of assessing capacity and competency to make medical, legal, and financial decisions in dementia patients with impaired decision making. While such assessments have classically focused on the capacity for complex reasoning and executive functions, research in decision making has revealed that motivational and metacognitive processes are also important. We first briefly review the neuropsychological literature on decision making and on the medical and legal assessment of capacity. Next, we discuss the limitations of integrating findings from decision-making research into capacity assessments, including the group-to-individual inference problem, the unclear role of neuroimaging in capacity assessments, and the lack of capacity measures that integrate important facets of decision making. Finally, we present several case examples where we attempt to demonstrate the potential benefits and important limitations of using decision-making research to aid in capacity determinations.

  10. PlanJury: probabilistic plan evaluation revisited

    Witte, M.; Sonke, J.-J.; van Herk, M.

    2014-03-01

    Purpose: Over a decade ago, the 'Van Herk margin recipe paper' introduced plan evaluation through DVH statistics based on population distributions of systematic and random errors. We extended this work for structures with correlated uncertainties (e.g. lymph nodes or parotid glands), and considered treatment plans containing multiple (overlapping) dose distributions (e.g. conventional lymph node and hypo-fractionated tumor doses) for which different image guidance protocols may lead to correlated errors. Methods: A command-line software tool 'PlanJury' was developed which reads 3D dose and structure data exported from a treatment planning system. Uncertainties are specified by standard deviations and correlation coefficients. Parameters control the DVH statistics to be computed: e.g. the probability of reaching a DVH constraint, or the dose absorbed at given confidence in a (combined) volume. Code was written in C++ and parallelized using OpenMP. Testing geometries were constructed using idealized spherical volumes and dose distributions. Results: Negligible stochastic noise could be attained within two minutes computation time for a single target. The confidence to properly cover both of two targets was 90% for two synchronously moving targets, but decreased by 7% if the targets moved independently. For two partially covered organs at risk the confidence of at least one organ below the mean dose threshold was 40% for synchronous motion, 36% for uncorrelated motion, but only 20% for either of the organs separately. Two abutting dose distributions ensuring 91% confidence of proper target dose for correlated motions led to 28% lower confidence for uncorrelated motions as relative displacements between the doses resulted in cold spots near the target. Conclusions: Probabilistic plan evaluation can efficiently be performed for complicated treatment planning situations, thus providing important plan quality information unavailable in conventional PTV based evaluations.

  11. Integrated capacity and inventory management with capacity acquisition lead times

    Mincsovics, G.Z.; Tan, T.; Alp, O.

    2009-01-01

    We model a make-to-stock production system that utilizes permanent and contingent capacity to meet non-stationary stochastic demand, where a constant lead time is associated with the acquisition of contingent capacity. We determine the structure of the optimal solution concerning both the

  12. Strategies to overcome barriers to implementing osteoporosis and fracture prevention guidelines in long-term care: a qualitative analysis of action plans suggested by front line staff in Ontario, Canada.

    Alamri, Sultan H; Kennedy, Courtney C; Marr, Sharon; Lohfeld, Lynne; Skidmore, Carly J; Papaioannou, Alexandra

    2015-08-01

    Osteoporosis is a major global health problem, especially among long-term care (LTC) facilities. Despite the availability of effective clinical guidelines to prevent osteoporosis and bone fractures, few LTC homes actually adhere to these practical recommendations. The purpose of this study was to identify barriers to the implementation of evidence-based practices for osteoporosis and fracture prevention in LTC facilities and elicit practical strategies to address these barriers. We performed a qualitative analysis of action plans formulated by Professional Advisory Committee (PAC) teams at 12 LTC homes in the intervention arm of the Vitamin D and Osteoporosis Study (ViDOS) in Ontario, Canada. PAC teams were comprised of medical directors, administrators, directors of care, pharmacists, dietitians, and other staff. Thematic content analysis was performed to identify the key themes emerging from the action plans. LTC teams identified several barriers, including lack of educational information and resources prior to the ViDOS intervention, difficulty obtaining required patient information for fracture risk assessment, and inconsistent prescribing of vitamin D and calcium at the time of admission. The most frequently suggested recommendations was to establish and adhere to standard admission orders regarding vitamin D, calcium, and osteoporosis therapies, improve the use of electronic medical records for osteoporosis and fracture risk assessment, and require bone health as a topic at quarterly reviews and multidisciplinary conferences. This qualitative study identified several important barriers and practical recommendations for improving the implementation of osteoporosis and fracture prevention guidelines in LTC settings.

  13. Epistemic Planning

    Baral, Chitta; Bolander, Thomas; van Ditmarsch, Hans

    The seminar Epistemic Planning brought together the research communities of Dynamic Epistemic Logic, Knowledge Representation and Reasoning, and Automated Planning to address fundamental problems on the topic of epistemic planning. In the context of this seminar, dynamic epistemic logic...... investigates the formal semantics of communication and communicative actions, knowledge representation and reasoning focuses on theories of action and change, and automated planning investigates computational techniques and tools to generate plans. The original goals of the seminar were to develop benchmarks...... for epistemic planning, to explore the relationship between knowledge and belief in multi-agent epistemic planning, to develop models of agency and capability in epistemic planning and to explore action types and their representations (these originally separate goals were merged during the seminar), and finally...

  14. Quantitative analysis of investment allocation over various resources of health care systems by using views of product lines

    Tai, Guangfu; Williams, Peter

    2013-11-01

    Hospitals can be viewed as service enterprises, of which the primary function is to provide specific sets of diagnostic and therapeutic medical services to individual patients. Each patient has certain diagnosis and therapeutic attributes in common with some other patients. Thus, patients with similar medical attributes could be 'processed' in one 'product line' of medical services, and individual treatments for patients within one 'product line' can be regarded as incurring identical consumption of health care resources. This article presents a theoretical framing for resource planning and investment allocation of various resources from a macro perspective of costs that demonstrates the need to plan capacity at the disaggregated resource level. The result of a balanced line ('optimal') is compared with an alternative scheme of 'the same ratio composing of resources' under the same monetary constraints. Thus, it is demonstrated that planning at the disaggregated level affords much better use of resources than achieved in common practice of budget control by simple percentage increase/decrease in distributing a financial vote.

  15. Planning for seven generations: Energy planning of American Indian tribes

    Brookshire, Daniel; Kaza, Nikhil

    2013-01-01

    The prevalence of energy resources on American Indian lands, the links between energy management and tribal sovereignty, and recent federal government incentives make tribal energy planning an interesting case study for community energy planning in the US. This paper studies the strategic energy planning efforts, energy resource development, and energy efficiency policies established by tribes within the continental US. The paper analyzes the results of a survey of various tribes′ energy resource development and planning efforts and supplements the responses with publicly available information on resources, economics, and demographics. We find that incentives and advisory services from the federal government are key to developing the capacity of the tribes to pursue energy planning and energy resource development. These incentives largely avoid the misdeeds of past federal policy by promoting tribal control over energy planning and energy resource development efforts. Tribes with formal energy plans or visions are more likely to develop energy resources than tribes without them and are engaged in a more comprehensive and sustainable approach to energy resource development and energy efficiency. - Highlights: • American Indian tribal energy planning is an understudied topic. • Tribal energy planning is interconnected with tribal sovereignty and sustainability. • We report the results of a survey of energy planning and development efforts. • Federal Government assistance is critical to the efforts of the tribes. • Tribes with energy plans take a more comprehensive approach to energy resource development

  16. The G8 summit of Gleneagles (July 6-8, 2005) - the energy-climate action plan - the France-Algeria cooperation. The works of the national commission of the public debate about energy - the management of nuclear wastes - the EPR at Flamanville - the Cotentin-Maine VHV line. The oil prices surge during summer 2005, national and international reactions

    Lamy, J.; Locufier, A.; Vincent, C.; Bros, Th.; Delmestre, N.; Noilban, F.; Quintaine, Th.; Perrin, J.L.; Branche, Th.; Barthe, F.

    2006-01-01

    This issue of Energies et matieres premieres newsletter comprises five articles dealing with: 1 - the energy-climate action plan adopted by the presidents of the 8 more industrialized countries of the world (G8) during the Gleneagles summit (Scotland) in July 6-8, 2005. This action plan was discussed in association with five emerging countries, among the biggest energy consumers in the world; 2 - the works carried out by the national commission of the public debate on energy about the management of radioactive wastes. The article recalls the 3 axes of research (separation-transmutation, underground disposal and surface or sub-surface storage) and the planning of the preparation of the future project of radioactive management law which will be examined by the European parliament during the second quarter of 2006; 3 - the public debate about the setting up of the European pressurized reactor (EPR) at Flamanville (Cotentin, France); 4 - the public debate about the project of very-high voltage power line between Flamanville and Maine region for the reinforcement of the regional power grid; and 5 - the national and international reactions in front of the surge of oil prices during summer 2005. (J.S.)

  17. Management self assessment plan

    Debban, B.L.

    1998-01-30

    Duke Engineering and Services Hanford Inc., Spent Nuclear Fuel Project is responsible for the operation of fuel storage facilities. The SNF project mission includes the safe removal, processing and transportation of Spent Nuclear Fuel from 100 K Area fuel storage basins to a new Storage facility in the Hanford 200 East Area. Its mission is the modification of the 100 K area fuel storage facilities and the construction of two new facilities: the 100 K Area Cold Vacuum Drying Facility, and the 200 East Area Canister Storage Building. The management self assessment plan described in this document is scheduled to begin in April of 1999 and be complete in May of 1999. The management self assessment plan describes line management preparations for declaring that line management is ready to commence operations.

  18. Management self assessment plan

    Debban, B.L.

    1998-01-01

    Duke Engineering and Services Hanford Inc., Spent Nuclear Fuel Project is responsible for the operation of fuel storage facilities. The SNF project mission includes the safe removal, processing and transportation of Spent Nuclear Fuel from 100 K Area fuel storage basins to a new Storage facility in the Hanford 200 East Area. Its mission is the modification of the 100 K area fuel storage facilities and the construction of two new facilities: the 100 K Area Cold Vacuum Drying Facility, and the 200 East Area Canister Storage Building. The management self assessment plan described in this document is scheduled to begin in April of 1999 and be complete in May of 1999. The management self assessment plan describes line management preparations for declaring that line management is ready to commence operations

  19. Forecast Mekong 2012: Building scientific capacity

    Stefanov, James E.

    2012-01-01

    In 2009, U.S. Secretary of State Hillary R. Clinton joined the Foreign Ministers of Cambodia, Laos, Thailand, and Vietnam in launching the Lower Mekong Initiative to enhance U.S. engagement with the countries of the Lower Mekong River Basin in the areas of environment, health, education, and infrastructure. The U.S. Geological Survey Forecast Mekong supports the Lower Mekong Initiative through a variety of activities. The principal objectives of Forecast Mekong include the following: * Build scientific capacity in the Lower Mekong Basin and promote cooperation and collaboration among scientists working in the region. * Provide data, information, and scientific models to help resource managers there make informed decisions. * Produce forecasting and visualization tools to support basin planning, including climate change adaptation. The focus of this product is Forecast Mekong accomplishments and current activities related to the development of scientific capacity at organizations and institutions in the region. Building on accomplishments in 2010 and 2011, Forecast Mekong continues to enhance scientific capacity in the Lower Mekong Basin with a suite of activities in 2012.

  20. The capacity credit of micro-combined heat and power

    Hawkes, A.D.; Leach, M.A.

    2008-01-01

    This article is concerned with development of a methodology to determine the capacity credit of micro-combined heat and power (micro-CHP), and application of the method for the UK. Capacity credit is an important parameter in electricity system planning because it measures the amount of conventional generation that would be displaced by an alternative technology. Firstly, a mathematical formulation is presented. Capacity credit is then calculated for three types of micro-CHP units-Stirling engine, internal combustion engine, and fuel cell systems-operating under various control strategies. It is found that low heat-to-power ratio fuel cell technologies achieve the highest capacity credit of approximately 85% for a 1.1 GW penetration when a heat-led control strategy is applied. Higher heat-to-power ratio Stirling engine technology achieves approximately 33% capacity credit for heat-led operation. Low heat-to-power ratio technologies achieve higher capacity credit because they are able to continue operating even when heat demand is relatively low. Capacity credit diminishes as penetration of the technology increases. Overall, the high capacity credit of micro-CHP contributes to the viewpoint that the technology can help meet a number of economic and environmental energy policy aims

  1. Integrated Glass Coating Manufacturing Line

    Brophy, Brenor [Enki Technology Inc., San Jose, CA (United States)

    2015-09-30

    This project aims to enable US module manufacturers to coat glass with Enki’s state of the art tunable functionalized AR coatings at the lowest possible cost and highest possible performance by encapsulating Enki’s coating process in an integrated tool that facilitates effective process improvement through metrology and data analysis for greater quality and performance while reducing footprint, operating and capital costs. The Phase 1 objective was a fully designed manufacturing line, including fully specified equipment ready for issue of purchase requisitions; a detailed economic justification based on market prices at the end of Phase 1 and projected manufacturing costs and a detailed deployment plan for the equipment.

  2. Microwave line of sight link engineering

    Angueira, Pablo

    2012-01-01

    A comprehensive guide to the design, implementation, and operation of line of sight microwave link systems The microwave Line of Sight (LOS) transport network of any cellular operator requires at least as much planning effort as the cellular infrastructure itself. The knowledge behind this design has been kept private by most companies and has not been easy to find. Microwave Line of Sight Link Engineering solves this dilemma. It provides the latest revisions to ITU reports and recommendations, which are not only key to successful design but have changed dramatically in

  3. Paraffin dispersant application for cleaning subsea flow lines in the deep water Gulf of Mexico cottonwood development

    Jennings, David; White, Jake; Pogoson, Oje [Baker Hughes Inc., Houston, TX (United States); Barros, Dalmo; Ramachandran, Kartik; Bonin, George; Waltrich, Paulo; Shecaira, Farid [PETROBRAS America, Houston, TX (United States); Ziglio, Claudio [Petroleo Brasileiro S.A. (CENPES/PETROBRAS), Rio de Janeiro, RJ (Brazil). Centro de Pesquisa e Desenvolvimento

    2012-07-01

    This paper discusses a paraffin dispersant (in seawater) application to clean paraffin deposition from a severely restricted 17.4-mile dual subsea flow line system in the Gulf of Mexico Cottonwood development. In principle, dispersant treatments are simple processes requiring effective dispersant packages and agitation to break-up and disperse deposition. Dispersants have been used onshore for treating wax deposition for decades. Implementation of a treatment in a long deep water production system, however, poses numerous challenges. The Cottonwood application was one of the first ever deep water dispersant applications. The application was designed in four separate phases: pre-treatment displacement for hydrate protection, dispersant treatment for paraffin deposition removal, pigging sequence for final flow line cleaning, and post-treatment displacement for hydrate protection. In addition, considerable job planning was performed to ensure the application was executed in a safe and environmentally responsible manner. Two dynamically positioned marine vessels were used for pumping fluids and capturing returns. The application was extremely successful in restoring the deep water flow lines back to near pre-production state. Final pigging operations confirmed the flow lines were cleaned of all restrictions. Significant paraffin deposition was removed in the application. Approximately 900 bbls of paraffin sludge was recovered from the 4000 bbl internal volume flow line loop. Furthermore, the application was completed with zero discharge of fluids. The application provided significant value for the Cottonwood development. It allowed production from wells to be brought on-line at a higher capacity, thereby generating increased revenue. It also allowed resumption of routine pigging operations. As such, the Cottonwood dispersant application illustrates that with proper planning and execution, paraffin dispersant treatments can be highly effective solutions for cleaning

  4. VT Electric Transmission Line Corridors - corridor lines

    Vermont Center for Geographic Information — (Link to Metadata) The ELTRN layer depicts electric transmission line corridors in Vermont. Various methods have been used to digitize features. The data layer...

  5. Assessment of Stochastic Capacity Consumption in Railway Networks

    Jensen, Lars Wittrup; Landex, Alex; Nielsen, Otto Anker

    2015-01-01

    The railway industry continuously strive to reduce cost and utilise resources optimally. Thus, there is a demand for tools that are able to fast and efficiently provide decision-makers with solutions that can help them achieve their goals. In strategic planning of capacity, this translates...

  6. Heat capacity of NdB.sub.6./sub..

    Reiffers, M.; Šebek, Josef; Šantavá, Eva; Shitsevalova, N.; Gabáni, S.; Pristáš, G.; Flachbart, K.

    2007-01-01

    Roč. 310, - (2007), e595-e597 ISSN 0304-8853 Institutional research plan: CEZ:AV0Z10100520 Keywords : heat capacity * NdB 6 * magnetic contribution Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.704, year: 2007

  7. Model study on steady heat capacity in driven stochastic systems

    Pešek, Jiří; Boksenbojm, E.; Netočný, Karel

    2012-01-01

    Roč. 10, č. 3 (2012), 692-701 ISSN 1895-1082 Institutional research plan: CEZ:AV0Z10100520 Keywords : nonequilibrium steady state * quasistatic process * heat capacity Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.905, year: 2012

  8. Installed capacity in New York

    Charlton, J.

    2006-01-01

    This presentation discussed capacity issues related to the New York Independent System Operator (NYISO). The NYISO's market volume was approximately $11 billion in 2005, and it was responsible for providing 32,075 MW of electricity at peak load to its users. Regulatory uncertainty is currently discouraging investment in new generating resources. All load serving entities are required to contract for sufficient capacity in order to meet their capacity obligations. Market participants currently determine capacity and energy revenues. The NYISO market allows suppliers to recover variable costs for providing ancillary services, and the economic value of the revenue source governs decisions made in the wholesale electricity market. The installed capacity market was designed as a spot auction deficiency auction. Phased-in demand curves are used to modify the installed capacity market's design. A sloped demand curve mechanism is used to value capacity above the minimum requirement for both reliability and competition. Participation in the day-ahead market enhances competition and exerts downward pressure on energy and ancillary service market prices. It was concluded that the market structures and design features of the installed capacity markets recognize the need for system reliability in addition to encouraging robust competition and recognizing energy price caps and regulatory oversights. tabs., figs

  9. Concrete Operations and Attentional Capacity.

    Chapman, Michael; Lindenberger, Ulman

    1989-01-01

    To test predictions regarding the attentional capacity requirements of Piaget's stage of concrete operations, a battery of concrete operational tasks and two measures of attentional capacity were administered to 120 first-, second-, and third-graders. Findings concern class inclusion, transitivity of length and weight, and multiplication of…

  10. Fiscal Capacity Equalisation in Tanzania

    Allers, Maarten A.; Ishemoi, Lewis J.

    2010-01-01

    Fiscal equalisation aims at enabling decentralised governments to supply similar services at similar tax rates. In order to equalise fiscal disparities, differences in both fiscal capacities and in fiscal needs have to be measured. This paper focuses on the measurement of fiscal capacity in a

  11. Computer-Assisted School Facility Planning with ONPASS.

    Urban Decision Systems, Inc., Los Angeles, CA.

    The analytical capabilities of ONPASS, an on-line computer-aided school facility planning system, are described by its developers. This report describes how, using the Canoga Park-Winnetka-Woodland Hills Planning Area as a test case, the Department of City Planning of the city of Los Angeles employed ONPASS to demonstrate how an on-line system can…

  12. Surge capacity logistics: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement.

    Einav, Sharon; Hick, John L; Hanfling, Dan; Erstad, Brian L; Toner, Eric S; Branson, Richard D; Kanter, Robert K; Kissoon, Niranjan; Dichter, Jeffrey R; Devereaux, Asha V; Christian, Michael D

    2014-10-01

    Successful management of a pandemic or disaster requires implementation of preexisting plans to minimize loss of life and maintain control. Managing the expected surges in intensive care capacity requires strategic planning from a systems perspective and includes focused intensive care abilities and requirements as well as all individuals and organizations involved in hospital and regional planning. The suggestions in this article are important for all involved in a large-scale disaster or pandemic, including front-line clinicians, hospital administrators, and public health or government officials. Specifically, this article focuses on surge logistics-those elements that provide the capability to deliver mass critical care. The Surge Capacity topic panel developed 23 key questions focused on the following domains: systems issues; equipment, supplies, and pharmaceuticals; staffing; and informatics. Literature searches were conducted to identify studies upon which evidence-based recommendations could be made. The results were reviewed for relevance to the topic, and the articles were screened by two topic editors for placement within one of the surge domains noted previously. Most reports were small scale, were observational, or used flawed modeling; hence, the level of evidence on which to base recommendations was poor and did not permit the development of evidence-based recommendations. The Surge Capacity topic panel subsequently followed the American College of Chest Physicians (CHEST) Guidelines Oversight Committee's methodology to develop suggestion based on expert opinion using a modified Delphi process. This article presents 22 suggestions pertaining to surge capacity mass critical care, including requirements for equipment, supplies, and pharmaceuticals; staff preparation and organization; methods of mitigating overwhelming patient loads; the role of deployable critical care services; and the use of transportation assets to support the surge response

  13. Capacity Building in Land Administration

    Enemark, Stig; Williamson, I

    2004-01-01

    Capacity building increasingly seen as a key component of land administration projects in developing and countries in transition undertaken by the international development banks and individual country development assistance agencies. However, the capacity building concept is often used within...... infrastructures for implementing land policies in a sustainable way. Where a project is established to create land administration infrastructures in developing or transition countries, it is critical that capacity building is a mainstream component, not as an add-on, which is often the case. In fact such projects...... should be dealt with as capacity building projects in themselves.    The article introduces a conceptual analytical framework that provides some guidance when dealing with capacity building for land administration in support of a broader land policy agenda....

  14. Material requirements planning: a better way to plan material.

    Tomas, S

    1990-08-01

    MRP systems can benefit hospitals in their management of material. Systems provide the means to schedule surgical procedures, calculate material requirements, release orders, plan future capacity requirements, and release and track work orders. MRP can be a powerful tool if properly implemented. All it takes is individuals dedicated to maintaining the discipline and data integrity required to make MRP successful.

  15. Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective.

    Metin Türkay

    Full Text Available Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers.

  16. Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective.

    Türkay, Metin; Saraçoğlu, Öztürk; Arslan, Mehmet Can

    2016-01-01

    Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers.

  17. Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective

    Türkay, Metin; Saraçoğlu, Öztürk; Arslan, Mehmet Can

    2016-01-01

    Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers. PMID:26807848

  18. Capacity flexibility allocation in an outsourced supply chain with reservation

    Boulaksil, Youssef; Grunow, Martin; Fransoo, J.C.

    2011-01-01

    We consider a contract manufacturer that serves a limited number of outsourcers (customers) on a single capacitated production line. the outsourcers have different levels of demand uncertainty and the contract manufacturer faces the question how to allocate the contractual capacity flexibility...... in an optimal way. The contractual capacity flexibility is a contract parameter that sets the amount of demand the contract manufacturer is obliged to accept from the outsourcers. We develop a hierachical model that consists of two decision levels. At the tactical level, the contract manufacturer allocates...... the capacity flexibility to the different outsourcers by maximizing the expected profit. Offering more flexibility to the more uncertain outsourcer generates higher expected revenue, but also increases the expected penalty costs. The allocated capacity flexibilities (determined at the tactical level) are input...

  19. Forward planning

    Fontenla, D.P.

    2008-01-01

    By definition, forward planning is a process where input consists of conditions on beam configurations and parameters and output consists of dose distributions on target and critical structures, in contrast to inverse planning, where the opposite is true. For forward planning IMRT, criteria are as follows: (i) Plans created as an extension of standard 3D conformational planning; (ii) No significant increase in the complexity of the treatment planning or treatment delivery process; (3) Treatment verification using standard QA procedures; and process consists of the following steps: (i) Create a standard 3D conformational treatment plan; (ii) Copy one of the existing beams; (iii) Create control points: design new beam segments, blocking high dose areas; (iv) Repeat for all beams; (v) Re-compute dose; and (vi) Adjust control points weights to achieve desired dose distribution. A detailed exposition, with many clinical examples, is given for the breast, lung, and brain (P.A.)

  20. Homotopic Polygonal Line Simplification

    Deleuran, Lasse Kosetski

    This thesis presents three contributions to the area of polygonal line simplification, or simply line simplification. A polygonal path, or simply a path is a list of points with line segments between the points. A path can be simplified by morphing it in order to minimize some objective function...

  1. Flight Planning in the Cloud

    Flores, Sarah L.; Chapman, Bruce D.; Tung, Waye W.; Zheng, Yang

    2011-01-01

    This new interface will enable Principal Investigators (PIs), as well as UAVSAR (Uninhabited Aerial Vehicle Synthetic Aperture Radar) members to do their own flight planning and time estimation without having to request flight lines through the science coordinator. It uses an all-in-one Google Maps interface, a JPL hosted database, and PI flight requirements to design an airborne flight plan. The application will enable users to see their own flight plan being constructed interactively through a map interface, and then the flight planning software will generate all the files necessary for the flight. Afterward, the UAVSAR team can then complete the flight request, including calendaring and supplying requisite flight request files in the expected format for processing by NASA s airborne science program. Some of the main features of the interface include drawing flight lines on the map, nudging them, adding them to the current flight plan, and reordering them. The user can also search and select takeoff, landing, and intermediate airports. As the flight plan is constructed, all of its components are constantly being saved to the database, and the estimated flight times are updated. Another feature is the ability to import flight lines from previously saved flight plans. One of the main motivations was to make this Web application as simple and intuitive as possible, while also being dynamic and robust. This Web application can easily be extended to support other airborne instruments.

  2. Computerized radiation treatment planning

    Laarse, R. van der.

    1981-01-01

    Following a general introduction, a chain consisting of three computer programs which has been developed for treatment planning of external beam radiotherapy without manual intervention is described. New score functions used for determination of optimal incidence directions are presented and the calculation of the position of the isocentre for each optimum combination of incidence directions is explained. A description of how a set of applicators, covering fields with dimensions of 4 to 20 cm, for the 6 to 20 MeV electron beams of a MEL SL75-20 linear accelerator was developed, is given. A computer program for three dimensional electron beam treatment planning is presented. A microprocessor based treatment planning system for the Selectron remote controlled afterloading system for intracavitary radiotherapy is described. The main differences in treatment planning procedures for external beam therapy with neutrons instead of photons is discussed. A microprocessor based densitometer for plotting isodensity lines in film dosimetry is described. A computer program for dose planning of brachytherapy is presented. Finally a general discussion about the different aspects of computerized treatment planning as presented in this thesis is given. (Auth.)

  3. The structure of Valdivia compact lines

    Kalenda, O.F.K.; Kubiś, Wieslaw

    2010-01-01

    Roč. 157, č. 7 (2010), s. 1142-1151 ISSN 0166-8641 R&D Projects: GA AV ČR IAA100190901 Institutional research plan: CEZ:AV0Z10190503 Keywords : valdivia compact line * increasing map * retraction Subject RIV: BA - General Mathematics Impact factor: 0.447, year: 2010 http://www.sciencedirect.com/science/article/pii/S0166864110000374

  4. Interference and memory capacity limitations.

    Endress, Ansgar D; Szabó, Szilárd

    2017-10-01

    Working memory (WM) is thought to have a fixed and limited capacity. However, the origins of these capacity limitations are debated, and generally attributed to active, attentional processes. Here, we show that the existence of interference among items in memory mathematically guarantees fixed and limited capacity limits under very general conditions, irrespective of any processing assumptions. Assuming that interference (a) increases with the number of interfering items and (b) brings memory performance to chance levels for large numbers of interfering items, capacity limits are a simple function of the relative influence of memorization and interference. In contrast, we show that time-based memory limitations do not lead to fixed memory capacity limitations that are independent of the timing properties of an experiment. We show that interference can mimic both slot-like and continuous resource-like memory limitations, suggesting that these types of memory performance might not be as different as commonly believed. We speculate that slot-like WM limitations might arise from crowding-like phenomena in memory when participants have to retrieve items. Further, based on earlier research on parallel attention and enumeration, we suggest that crowding-like phenomena might be a common reason for the 3 major cognitive capacity limitations. As suggested by Miller (1956) and Cowan (2001), these capacity limitations might arise because of a common reason, even though they likely rely on distinct processes. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  5. Rehabilitation medicine summit: building research capacity Executive Summary

    Kemp John D

    2006-01-01

    Full Text Available Abstract The general objective of the "Rehabilitation Medicine Summit: Building Research Capacity" was to advance and promote research in medical rehabilitation by making recommendations to expand research capacity. The five elements of research capacity that guided the discussions were: 1 researchers; 2 research culture, environment, and infrastructure; 3 funding; 4 partnerships; and 5 metrics. The 100 participants included representatives of professional organizations, consumer groups, academic departments, researchers, governmental funding agencies, and the private sector. The small group discussions and plenary sessions generated an array of problems, possible solutions, and recommended actions. A post-Summit, multi-organizational initiative is called to pursue the agendas outlined in this report (see Additional File 1. Additional File 1 A table outlining the Final Action Plan of the Rehabilitation Medicine Summit: Building Research Capacity held on April 28–29, 2005 in Washington, DC. Click here for file

  6. Modeling Coevolution between Language and Memory Capacity during Language Origin

    Gong, Tao; Shuai, Lan

    2015-01-01

    Memory is essential to many cognitive tasks including language. Apart from empirical studies of memory effects on language acquisition and use, there lack sufficient evolutionary explorations on whether a high level of memory capacity is prerequisite for language and whether language origin could influence memory capacity. In line with evolutionary theories that natural selection refined language-related cognitive abilities, we advocated a coevolution scenario between language and memory capacity, which incorporated the genetic transmission of individual memory capacity, cultural transmission of idiolects, and natural and cultural selections on individual reproduction and language teaching. To illustrate the coevolution dynamics, we adopted a multi-agent computational model simulating the emergence of lexical items and simple syntax through iterated communications. Simulations showed that: along with the origin of a communal language, an initially-low memory capacity for acquired linguistic knowledge was boosted; and such coherent increase in linguistic understandability and memory capacities reflected a language-memory coevolution; and such coevolution stopped till memory capacities became sufficient for language communications. Statistical analyses revealed that the coevolution was realized mainly by natural selection based on individual communicative success in cultural transmissions. This work elaborated the biology-culture parallelism of language evolution, demonstrated the driving force of culturally-constituted factors for natural selection of individual cognitive abilities, and suggested that the degree difference in language-related cognitive abilities between humans and nonhuman animals could result from a coevolution with language. PMID:26544876

  7. Large capacity temporary visual memory

    Endress, Ansgar D.; Potter, Mary C.

    2014-01-01

    Visual working memory (WM) capacity is thought to be limited to three or four items. However, many cognitive activities seem to require larger temporary memory stores. Here, we provide evidence for a temporary memory store with much larger capacity than past WM capacity estimates. Further, based on previous WM research, we show that a single factor — proactive interference — is sufficient to bring capacity estimates down to the range of previous WM capacity estimates. Participants saw a rapid serial visual presentation (RSVP) of 5 to 21 pictures of familiar objects or words presented at rates of 4/s or 8/s, respectively, and thus too fast for strategies such as rehearsal. Recognition memory was tested with a single probe item. When new items were used on all trials, no fixed memory capacities were observed, with estimates of up to 9.1 retained pictures for 21-item lists, and up to 30.0 retained pictures for 100-item lists, and no clear upper bound to how many items could be retained. Further, memory items were not stored in a temporally stable form of memory, but decayed almost completely after a few minutes. In contrast, when, as in most WM experiments, a small set of items was reused across all trials, thus creating proactive interference among items, capacity remained in the range reported in previous WM experiments. These results show that humans have a large-capacity temporary memory store in the absence of proactive interference, and raise the question of whether temporary memory in everyday cognitive processing is severely limited as in WM experiments, or has the much larger capacity found in the present experiments. PMID:23937181

  8. Capacity-achieving CPM schemes

    Perotti, Alberto; Tarable, Alberto; Benedetto, Sergio; Montorsi, Guido

    2008-01-01

    The pragmatic approach to coded continuous-phase modulation (CPM) is proposed as a capacity-achieving low-complexity alternative to the serially-concatenated CPM (SC-CPM) coding scheme. In this paper, we first perform a selection of the best spectrally-efficient CPM modulations to be embedded into SC-CPM schemes. Then, we consider the pragmatic capacity (a.k.a. BICM capacity) of CPM modulations and optimize it through a careful design of the mapping between input bits and CPM waveforms. The s...

  9. Informed, advance refusals of treatment by people with severe mental illness in a randomised controlled trial of joint crisis plans: demand, content and correlates.

    Henderson, Claire; Farrelly, Simone; Flach, Clare; Borschmann, Rohan; Birchwood, Max; Thornicroft, Graham; Waheed, Waquas; Szmukler, George

    2017-11-24

    In the UK, crisis planning for mental health care should acknowledge the right to make an informed advance treatment refusal under the Mental Capacity Act 2005. Our aims were to estimate the demand for such treatment refusals within a sample of service users who had had a recent hospital admission for psychosis or bipolar disorder, and to examine the relationship between refusals, and service user characteristics. To identify refusals we conducted content analysis of Joint Crisis Plans, which are plans formulated by service users and their clinical team with involvement from an external facilitator, and routine care plans in sub-samples from a multi-centre randomised controlled trial of Joint Crisis Plans (plus routine mental health care) versus routine care alone (CRIMSON) in England. Factors hypothesised to be associated with refusals were identified using the trial data collected through baseline interviews of service users and clinicians and collection of routine clinical data. Ninety-nine of 221 (45%) of the Joint Crisis Plans contained a treatment refusal compared to 10 of 424 (2.4%) baseline routine care plans. No Joint Crisis Plans recorded disagreement with refusals on the part of clinicians. Among those with completed Joint Crisis Plans, adjusted analyses indicated a significant association between treatment refusals and perceived coercion at baseline (odds ratio = 1.21, 95% CI 1.02-1.43), but not with baseline working alliance or a past history of involuntary admission. We demonstrated significant demand for written treatment refusals in line with the Mental Capacity Act 2005, which had not previously been elicited by the process of treatment planning. Future treatment/crisis plans should incorporate the opportunity for service users to record a treatment refusal during the drafting of such plans. ISRCTN11501328 Registered 13th March 2008.

  10. Pacific Basin Heavy Oil Refining Capacity

    David Hackett

    2013-02-01

    Full Text Available The United States today is Canada’s largest customer for oil and refined oil products. However, this relationship may be strained due to physical, economic and political influences. Pipeline capacity is approaching its limits; Canadian oil is selling at substantive discounts to world market prices; and U.S. demand for crude oil and finished products (such as gasoline, has begun to flatten significantly relative to historical rates. Lower demand, combined with increased shale oil production, means U.S. demand for Canadian oil is expected to continue to decline. Under these circumstances, gaining access to new markets such as those in the Asia-Pacific region is becoming more and more important for the Canadian economy. However, expanding pipeline capacity to the Pacific via the proposed Northern Gateway pipeline and the planned Trans Mountain pipeline expansion is only feasible when there is sufficient demand and processing capacity to support Canadian crude blends. Canadian heavy oil requires more refining and produces less valuable end products than other lighter and sweeter blends. Canadian producers must compete with lighter, sweeter oils from the Middle East, and elsewhere, for a place in the Pacific Basin refineries built to handle heavy crude blends. Canadian oil sands producers are currently expanding production capacity. Once complete, the Northern Gateway pipeline and the Trans Mountain expansion are expected to deliver an additional 500,000 to 1.1 million barrels a day to tankers on the Pacific coast. Through this survey of the capacity of Pacific Basin refineries, including existing and proposed facilities, we have concluded that there is sufficient technical capacity in the Pacific Basin to refine the additional Canadian volume; however, there may be some modifications required to certain refineries to allow them to process Western Canadian crude. Any additional capacity for Canadian oil would require refinery modifications or

  11. Reasons for decision in the matter of Enbridge Pipelines Inc. Line 4 Extension Project : facilities[Application dated 28 June 2007 for the Line 4 Extension Project

    NONE

    2008-04-15

    In June 2007, Enbridge Pipelines Inc. applied for approval to extend Line 4 of its Mainline pipeline upstream from Hardisty to Edmonton, Alberta. The project would relieve a potential bottleneck and would also add an additional line across this segment to increase system security and flexibility. The average annual capacity of Line 4 would be 140,000 cubic metres per day. The Enbridge Mainline from Edmonton to Hardisty currently includes 3 oil pipelines, while the Enbridge Mainline downstream of Hardisty includes 4 oil pipelines. This document presented the views of the Board regarding the construction and operation of the project facilities; public and Aboriginal consultation; environmental and socio-economic matters; land matters; tolls and tariffs; and, supply, markets, financing and economics. The Board noted that the benefits of this project outweigh the burdens associated with it. The project required an environmental assessment under the Canadian Environmental Assessment Act which found that it is not likely to cause significant adverse environmental effects. In its approval of the project, the Board attached 15 conditions, including a requirement for Enbridge to file an updated Environmental Protection Plan for the Board's approval. The Board also approved Enbridge's application for its tolling method and to reactivate 3 sections of pre-existing pipeline. 3 tabs., 3 figs., 3 appendices.

  12. Philippines revises power plans

    Hayes, D.

    1988-02-01

    Following an unexpected surge in electricity demand the Philippines has revised its medium term power development programme. The sharp increase in electricity consumption follows three years of slack demand due to civil disturbances before the end of the Macros administration and the election of Corazon Aquino as President in 1986. Originally, the Aquino government's medium term power development plans called for about 500MW of generating capacity to be installed between 1986 and 1992. The three proposed plants were scheduled for commissioning in 1991 and 1992. However, a spurt in power demand growth during the past nine months has caused concern among industrialists that power shortages could occur by the end of the decade. So additional capacity will be installed to prevent an anticipated shortfall in electricity supplies by the early 1990s.

  13. Analysis of Load-Carrying Capacity for Redundant Free-Floating Space Manipulators in Trajectory Tracking Task

    Qingxuan Jia

    2014-01-01

    Full Text Available The aim of this paper is to analyze load-carrying capacity of redundant free-floating space manipulators (FFSM in trajectory tracking task. Combined with the analysis of influential factors in load-carrying process, evaluation of maximum load-carrying capacity (MLCC is described as multiconstrained nonlinear programming problem. An efficient algorithm based on repeated line search within discontinuous feasible region is presented to determine MLCC for a given trajectory of the end-effector and corresponding joint path. Then, considering the influence of MLCC caused by different initial configurations for the starting point of given trajectory, a kind of maximum payload initial configuration planning method is proposed by using PSO algorithm. Simulations are performed for a particular trajectory tracking task of the 7-DOF space manipulator, of which MLCC is evaluated quantitatively. By in-depth research of the simulation results, significant gap between the values of MLCC when using different initial configurations is analyzed, and the discontinuity of allowable load-carrying capacity is illustrated. The proposed analytical method can be taken as theoretical foundation of feasibility analysis, trajectory optimization, and optimal control of trajectory tracking task in on-orbit load-carrying operations.

  14. Transformational capacity and the influence of place and identity

    Marshall, N A; Park, S E; Howden, S M; Adger, W N; Brown, K

    2012-01-01

    Climate change is altering the productivity of natural resources with far-reaching implications for those who depend on them. Resource-dependent industries and communities need the capacity to adapt to a range of climate risks if they are to remain viable. In some instances, the scale and nature of the likely impacts means that transformations of function or structure will be required. Transformations represent a switch to a distinct new system where a different suite of factors become important in the design and implementation of response strategies. There is a critical gap in knowledge on understanding transformational capacity and its influences. On the basis of current knowledge on adaptive capacity we propose four foundations for measuring transformational capacity: (1) how risks and uncertainty are managed, (2) the extent of skills in planning, learning and reorganizing, (3) the level of financial and psychological flexibility to undertake change and (4) the willingness to undertake change. We test the influence of place attachment and occupational identity on transformational capacity using the Australian peanut industry, which is presently assessing significant structural change in response to predicted climatic changes. Survey data from 88% of peanut farmers in Queensland show a strong negative correlation between transformational capacity and both place attachment and occupational attachment, suggesting that whilst these factors may be important positive influences on the capacity to adapt to incremental change, they act as barriers to transformational change. (letter)

  15. Transformational capacity and the influence of place and identity

    Marshall, N. A.; Park, S. E.; Adger, W. N.; Brown, K.; Howden, S. M.

    2012-09-01

    Climate change is altering the productivity of natural resources with far-reaching implications for those who depend on them. Resource-dependent industries and communities need the capacity to adapt to a range of climate risks if they are to remain viable. In some instances, the scale and nature of the likely impacts means that transformations of function or structure will be required. Transformations represent a switch to a distinct new system where a different suite of factors become important in the design and implementation of response strategies. There is a critical gap in knowledge on understanding transformational capacity and its influences. On the basis of current knowledge on adaptive capacity we propose four foundations for measuring transformational capacity: (1) how risks and uncertainty are managed, (2) the extent of skills in planning, learning and reorganizing, (3) the level of financial and psychological flexibility to undertake change and (4) the willingness to undertake change. We test the influence of place attachment and occupational identity on transformational capacity using the Australian peanut industry, which is presently assessing significant structural change in response to predicted climatic changes. Survey data from 88% of peanut farmers in Queensland show a strong negative correlation between transformational capacity and both place attachment and occupational attachment, suggesting that whilst these factors may be important positive influences on the capacity to adapt to incremental change, they act as barriers to transformational change.

  16. Inspection planning

    Korosec, D.; Levstek, M.F.

    2001-01-01

    Slovenian Nuclear Safety Administration (SNSA) division of nuclear and radiological safety inspection has developed systematic approach to their inspections. To be efficient in their efforts regarding regular and other types of inspections, in past years, the inspection plan has been developed. It is yearly based and organized on a such systematic way, that all areas of nuclear safety important activities of the licensee are covered. The inspection plan assures appropriate preparation for conducting the inspections, allows the overview of the progress regarding the areas to be covered during the year. Depending on the licensee activities and nature of facility (nuclear power plant, research reactor, radioactive waste storage, others), the plan has different levels of intensity of inspections and also their frequency. One of the basic approaches of the plan is to cover all nuclear and radiological important activities on such way, that all regulatory requests are fulfilled. In addition, the inspection plan is a good tool to improve inspection effectiveness based on previous experience and allows to have the oversight of the current status of fulfillment of planned inspections. Future improvement of the plan is necessary in the light of newest achievements on this field in the nuclear world, that means, new types of inspections are planned and will be incorporated into plan in next year.(author)

  17. World nuclear power plant capacity

    Anon.

    1981-01-01

    Worldwide, there were 249 power reactors in operation at the end of 1980, with a net electrical capacity of about 142 GW. In Canada the ten reactors in operation had a combined capacity of about 5.5 GW. Another 14 under construction will produce an additional 9.9 GW. Four Canadian reactors were in the world's top ten in terms of capacity factor in 1980, and six were in the top ten in terms of lifetime performance. Data tabulated for the Canadian reactors are: location, power, operator, date of first power. For the rest of the world, a table gives the number of reactors of each type and their capacity. (N.D.H.)

  18. EIA models and capacity building in Viet Nam: an analysis of development aid programs

    Doberstein, Brent

    2004-01-01

    There has been a decided lack of empirical research examining development aid agencies as 'agents of change' in environmental impact assessment (EIA) systems in developing countries, particularly research examining the model of environmental planning practice promoted by aid agencies as part of capacity building. This paper briefly traces a conceptual framework of EIA, then introduces the concept of 'EIA capacity building'. Using Viet Nam as a case study, the paper then outlines the empirical results of the research, focusing on the extent to which aid agency capacity-building programs promoted a Technical vs. Planning Model of EIA and on the coherence of capacity-building efforts across all aid programs. A discussion follows, where research results are interpreted within the Vietnamese context, and implications of research results are identified for three main groups of actors. The paper concludes by calling for development aid agencies to reconceptualise EIA capacity building as an opportunity to transform developing countries' development planning processes

  19. Flow lines and export lines of Sabalo Gas Field - the engineering of a complex job; Flow lines e export lines de Sabalo - a engenharia da complexidade

    Serodio, Conrado Jose Morbach [GDK Engenharia, Salvador, BA (Brazil)

    2003-07-01

    The construction of the natural gas flow lines and export lines system of the Sabalo field, in the far South of Bolivia is an unique job in the pipeline construction area. Its execution is a turning point in terms of engineering and construction technology in this industry. Among the Aguarague Cordillera (mountains), it runs across rocky canyons for more than 5 km, a 2.100 mt long narrow tunnel to overcome the mountains and steep hills along all the ROW length, with a total extension of 70 km, in line pipes ranging from 10'' and 12'' for the flow lines, 28'' for the gas export line and 8' for the condensate line. An integrated construction work plan was settled in order to face and overcome the complex construction situations found in every feet of the pipeline. Four simultaneous work sites were mobilized, 8 independent work fronts, 700 professionals and more than 150 pieces of heavy construction equipment, brought from 3 different countries. Special techniques were adopted also to handle the challenging detail engineering . All in all, the correct conjunction of a sound engineering work, planning, human resources and equipment and the managing flexibility to create alternatives and solutions at the fast pace required by a dynamic work schedule were essential to succeed, in a job with no room for mistakes. The successfully job completion open new possibilities to other challenging projects alike.(author)

  20. Building a capacity building manual

    Clinton, DD

    2010-02-01

    Full Text Available Organizations 2010 Building a capacity building manual Daniel D. Clinton, Jr., P.E., F.NSPE Chair, WFEO Capacity Building Committee Dr Andrew Cleland, FIPENZ, Chief Executive, IPENZ, NZ Eng David Botha, FSAICE, Executive Director, SAICE, SA Dawit... 2010 Tertiary level University curricula Coaches and mentors Facilities EXCeeD Remuneration of Academics Experiential training Outreach to Students Students chapters Young members forum World Federation of Engineering Organizations 2010 Post...