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Sample records for lehman brothers merrill

  1. The Failure of Lehman Brothers and Merril Lynch: A Lesson for the ...

    African Journals Online (AJOL)

    DR Nneka

    afrrev.v9i2.9. The Failure of Lehman Brothers and Merril Lynch: A Lesson for the Nigerian Banking Industry. Achugbu, Austine A. Department of Banking and Finance,. Anambra State University, Igbariam Campus,. Anambra State, Nigeria.

  2. The Lehman Brothers effect and bankruptcy cascades

    Science.gov (United States)

    Sieczka, P.; Sornette, D.; Holyst, J. A.

    2011-08-01

    Inspired by the bankruptcy of Lehman Brothers and its consequences on the global financial system, we develop a simple model in which the Lehman default event is quantified as having an almost immediate effect in worsening the credit worthiness of all financial institutions in the economic network. In our stylized description, all properties of a given firm are captured by its effective credit rating, which follows a simple dynamics of co-evolution with the credit ratings of the other firms in our economic network. The dynamics resembles the evolution of Potts spin-glass with external global field corresponding to a panic effect in the economy. The existence of a global phase transition, between paramagnetic and ferromagnetic phases, explains the large susceptibility of the system to negative shocks. We show that bailing out the first few defaulting firms does not solve the problem, but does have the effect of alleviating considerably the global shock, as measured by the fraction of firms that are not defaulting as a consequence. This beneficial effect is the counterpart of the large vulnerability of the system of coupled firms, which are both the direct consequences of the collective self-organized endogenous behaviors of the credit ratings of the firms in our economic network.

  3. Lecciones regulatorias de la quiebra de Lehman Brothers

    Directory of Open Access Journals (Sweden)

    William Black

    2010-09-01

    Full Text Available La quiebra de Lehman Brothers el 15 de septiembre de 2008 marcó un parteaguas en la actual crisis financiera/económica mundial. La decisión de las autoridades estadounidenses de no rescatar el banco ha sido objeto a un gran debate público y académico, pero casi siempre carente de una discusión a profundidad sobre el comportamiento del banco. William Black, un exregulador bancario reconocido por detectar los mayores fraudes durante la crisis bancaria de los Savings & Loan en los años ochenta en los Estados Unidos y uno de los criminólogo financiero más activos en la esfera pública estadounidense, ofrece al lector una visión de los negocios turbios de Lehman Brothers que le llevaron a su colapso. Con el respaldo de documentación pública, Black describe y analiza como Lehman Brothers actuaba como un “vector de fraude”, creando y recreando un ambiente criminal en el sector financiero que castiga al comportamiento honesto y premia el crimen financiero. Ese tema, central al entendimiento de la crisis, a la vez poco reconocido, se expone con la maestría de quien es uno de sus mejores conocedores.

  4. The Failure of Lehman Brothers and Merril Lynch: A Lesson for the ...

    African Journals Online (AJOL)

    Also the conventional lending procedures were not instituted rather they depend on subprime mortgage arrangement that did not have collateral securities. The declining home prices had made refinancing more difficult as a result of inadequate innovations in securitization. We therefore, recommended that the regulatory ...

  5. Information dissipation as an early-warning signal for the Lehman Brothers collapse in financial time series

    Science.gov (United States)

    Quax, Rick; Kandhai, Drona; Sloot, Peter M. A.

    2013-05-01

    In financial markets, participants locally optimize their profit which can result in a globally unstable state leading to a catastrophic change. The largest crash in the past decades is the bankruptcy of Lehman Brothers which was followed by a trust-based crisis between banks due to high-risk trading in complex products. We introduce information dissipation length (IDL) as a leading indicator of global instability of dynamical systems based on the transmission of Shannon information, and apply it to the time series of USD and EUR interest rate swaps (IRS). We find in both markets that the IDL steadily increases toward the bankruptcy, then peaks at the time of bankruptcy, and decreases afterwards. Previously introduced indicators such as `critical slowing down' do not provide a clear leading indicator. Our results suggest that the IDL may be used as an early-warning signal for critical transitions even in the absence of a predictive model.

  6. The Lehman Sisters Hypothesis

    NARCIS (Netherlands)

    I.P. van Staveren (Irene)

    2014-01-01

    markdownabstract__Abstract__ This article explores the Lehman Sisters Hypothesis. It reviews empirical literature about gender differences in behavioral, experimental, and neuro-economics as well as in other fields of behavioral research. It discusses gender differences along three dimensions of

  7. My Brother Warren.

    Science.gov (United States)

    Forbes, Eric

    1987-01-01

    The younger brother of a hyperactive, severely learning-disabled 21-year-old recounts his feelings regarding lack of parental attention, jealousy toward his older brother, embarrassment, and finally empathy for his older brother. (CB)

  8. The Lehman Sisters Hypothesis: an exploration of literature and bankers

    NARCIS (Netherlands)

    I.P. van Staveren (Irene)

    2012-01-01

    textabstractAbstract This article tests the Lehman Sisters Hypothesis in two complementary, although incomplete ways. It reviews the diverse empirical literature in behavioral, experimental, and neuroeconomics as well as related fields of behavioral research. And it presents the findings from an

  9. The Lehman Sisters Hypothesis: an exploration of literature and bankers

    NARCIS (Netherlands)

    I.P. van Staveren (Irene)

    2012-01-01

    textabstractThis article tests the Lehman Sisters Hypothesis in two complementary, although incomplete ways. It reviews the diverse empirical literature in behavioural, experimental, and neuroeconomics as well as related fields of behavioural research. And it presents the findings from an

  10. Macroeconomic Adjustment to the Lehman Shock in Japan

    Directory of Open Access Journals (Sweden)

    Kazumi Asako

    2010-06-01

    Full Text Available In this paper we overview the macroeconomic adjustment to the Lehman shock in Japan. After retrospecting the Japanese economy since the Plaza Accord which led Japan to the bubble economy and the 'lost decade' we explain the business cycles in Japan and show related macroeconomic indicators since as early as the 1980s. Then we trace the macroeconomic responses of the Japanese economy to the Lehman shock by selectively looking at such aspects as the contribution of GDP growth by expenditure components, from peak to trough of the CI(composite index, production and inventory adjustment, and employment adjustment. We also supplement our analyses by observing additional factors including export, investment, consumption, exchange rate, and the stock market. The roles played by policy measures and expectations formation are also emphasized to explain why and how the Japanese economy did not develop as forecasted against the 'once in a hundred years' crisis.

  11. Cryptorchidism concordance in monozygotic and dizygotic twin brothers, full brothers, and half-brothers

    DEFF Research Database (Denmark)

    Jensen, Morten Søndergaard; Toft, Gunnar; Thulstrup, Ane Marie

    2010-01-01

    to December 31, 2004. Classic twin method and computerized square dance design. SETTING: Hospitals and outpatient clinics. PATIENT(S): Six groups of boy pairs: boys with no relation, paternal half-brothers, maternal half-brothers, full brothers, dizygotic twin brothers, and monozygotic twin brothers...

  12. Brothers in Arms:

    DEFF Research Database (Denmark)

    Vincent, Stéphanie; Bingley, Paul; Lundborg, Petter

    Family members tend to have similar labor market outcomes, but measuring the contribution of behavioral spillovers is difficult. To identify spillovers between brothers, we exploit Denmark’s largest random assignment – of young men to 8 months of military service – where service status of brothers...

  13. 75 FR 71458 - Warner Brothers Entertainment, Inc., Warner Brothers Theatrical Enterprises, Including Workers of...

    Science.gov (United States)

    2010-11-23

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-71,775] Warner Brothers Entertainment, Inc., Warner Brothers Theatrical Enterprises, Including Workers of the Following Operating Entities: Burbank Television Enterprises LLC, Warner Brothers Consumer Products, Inc., Warner Brothers...

  14. 'Wrong but Impeccable': Lehman Wing, Metropolitan Museum of Art, New York

    Science.gov (United States)

    Huxtable, Ada Louise

    1975-01-01

    Although the new Lehman Wing of the Metropolitan Museum of Art was a controversial project based on a questionable premise, the finished building is an architectural tour de force. Despite restrictions imposed by the Landmarks Commission and the donor, the architects responded with consummate ingenuity, artistry, and skill. (JG)

  15. Efficient production of transgenic soybean (Glycine max [L] Merrill ...

    African Journals Online (AJOL)

    Efficient production of transgenic soybean (Glycine max [L] Merrill) plants mediated via whisker-supersonic (WSS) method. MM Khalafalla, HA El-Shemy, SM Rahman, M Teraishi, H Hasegawa, T Terakawa, M Ishimoto ...

  16. General Merrill A. McPeak Leadership and Organizational Change

    Science.gov (United States)

    2001-06-01

    GENERAL MERRILL A. MCPEAK LEADERSHIP AND ORGANIZATIONAL CHANGE BY MAJOR THOMAS A. BUSSIERE A THESIS PRESENTED TO THE...Covered (from... to) - Title and Subtitle General Merrill A. McPeak Leadership and Organizational Change Contract Number Grant Number Program Element...General McPeak�s leadership. The sections of each case focus on the particular issues associated with organizational change and leadership. The

  17. Joyce Brothers (1927-2013).

    Science.gov (United States)

    Farley, Frank

    2014-01-01

    Joyce Brothers died May 13, 2013, at age 85, in Fort Lee, New Jersey. She was born in Brooklyn, New York, on October 20, 1927. To the public, Joyce Brothers was the best known psychologist of her time. Brothers's influence on the media, and psychology, was considerable and varied. She became the public face of psychology. As her ascendency as a media psychologist progressed, she reinforced the ideas that a PhD psychologist is called "Doctor"; that a woman can create a career in the field and also raise a family; that there are psychological insights about human behavior that everyone can understand; and that psychologists are not always wearing laboratory coats or talking to people who lie on a couch, but can be lively, engaging, understandable, fun, and down-to-earth people. One might speculate that Joyce Brothers brought a lot of young women into careers in psychology. Brothers created an amazing career which she pursued with style and grace. Stepping outside of a traditional psychological career sometimes drew fire from the profession, in line with frequent criticism of popularizers in psychology and other fields. 2014 APA, all rights reserved

  18. China’s Debt Woes: Not Yet a “Lehman Moment”

    Directory of Open Access Journals (Sweden)

    Shalendra D. Sharma

    2015-03-01

    Full Text Available What explains the sharp increase in the Chinese economy's indebtedness, in particular the China's onshore corporate debt? Has the overall debt burden reached a threshold where it poses a systemic risk, thereby making the economy vulnerable to a "Lehman Moment" - with disorderly unwinding of the private sector and sovereign debt? What are the short and longer term implications of China's growing debt problems on domestic economic growth and the broader global political economy? What has Beijing done to ameliorate the problem, how effective were its efforts, and what must it do to deal with this problem?

  19. Bilateral breast in brothers - abreast

    Directory of Open Access Journals (Sweden)

    Altamash Mohammed Yusuf Shaikh

    2013-01-01

    Full Text Available Gynecomastia is a common occurrence in pubertal age group, and is physiological in up to 65 percent of cases. When occurs in the family it should be investigated in order not to miss on a treatable etiology. Two brothers within the same family, presenting with bilateral gynecomastia of different causes and requiring different treatment are presented.

  20. "I Loved My Brother Infinitely…"

    OpenAIRE

    Pavel Fokin

    2014-01-01

    Abstract Literary heritage of Mikhail Mikhailovich Dostoevsky(1820-1864) is not very abundant and appeals to experts only. His personality is of much more importance for national and world culture. He was a friend and soul mate of his genius brother (almost coeval). Their relations were an essential element of the biography and spiritual identity of Fyodor Dostoevsky. Mikhail was the first and for many years the only interlocutor of F.M. Dostoevsky. His role as an addressee in Fyodor Dosto...

  1. "I Loved My Brother Infinitely…"

    Directory of Open Access Journals (Sweden)

    Pavel Fokin

    2014-12-01

    Full Text Available Abstract Literary heritage of Mikhail Mikhailovich Dostoevsky(1820-1864 is not very abundant and appeals to experts only. His personality is of much more importance for national and world culture. He was a friend and soul mate of his genius brother (almost coeval. Their relations were an essential element of the biography and spiritual identity of Fyodor Dostoevsky. Mikhail was the first and for many years the only interlocutor of F.M. Dostoevsky. His role as an addressee in Fyodor Dostoevsky’s letters cannot be underestimated either. Fyodor Dostoevsky regarded his brother not only as a friend but as a business partner too. Their most successful joint enterprise was publishing of the magazine “Time” (“Vremya” (1861–1863, whose initiator and owner became Mikhail Dostoevsky. After Мikhail’s death Fyodor took charge of his family that had both direct and indirect impact on his own lifestyle. The year 2014 was the 150th anniversary of Mikhail Dostoevsky’s death. In this regard, the State Literature Museum organized an exposition titled “I loved my brother infinitely...” in the F.M. Dostoevsky Museum-Apartment. It was the first exposition dedicated to the personality of Mikhail Dostoevsky and his literary heritage. A lot of exhibit items had never been exposed before.

  2. Scott Brothers Windows and Doors Information Sheet

    Science.gov (United States)

    Scott Brothers Windows and Doors (the Company) is located in Bridgeville, Pennsylvania. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Pittsburgh, Pennsylvania.

  3. Nature vs. nurture: two brothers with schizophrenia.

    Science.gov (United States)

    Keltner, N L; James, C A; Darling, R J; Findley, L S; Oliver, K

    2001-01-01

    The nature vs. nurture argument as it pertains to two brothers. To explore the synergistic effects of heritability and environment in the cases of two brothers with schizophrenia. Review of the literature and the authors' clinical experience. The nature vs. nurture dichotomy may not be as relevant as looking at the interaction between these two forces.

  4. Climate change impacts on the Lehman-Baker Creek drainage in the Great Basin National Park

    Science.gov (United States)

    Volk, J. M.

    2013-12-01

    Global climate models (GCMs) forced by increased CO2 emissions forecast anomalously dry and warm trends over the southwestern U.S. for the 21st century. The effect of warmer conditions may result in decreased surface water resources within the Great Basin physiographic region critical for ecology, irrigation and municipal water supply. Here we use downscaled GCM output from the A2 and B1 greenhouse gas emission scenarios to force a Precipitation-Runoff Modeling System (PRMS) watershed model developed for the Lehman and Baker Creeks Drainage (LBCD) in the Great Basin National Park, NV for a century long time period. The goal is to quantify the effects of rising temperature to the water budget in the LBCD at monthly and annual timescales. Dynamically downscaled GCM projections are attained from the NSF EPSCoR Nevada Infrastructure for Climate Change Science, Education, and Outreach project and statistically downscaled output is retrieved from the "U.S. Bias Corrected and Downscaled WCRP CMIP3 Climate Projections". Historical daily climate and streamflow data have been collected simultaneously for periods extending 20 years or longer. Mann-Kendal trend test results showed a statistically significant (α= 0.05) long-term rising trend from 1895 to 2012 in annual and monthly average temperatures for the study area. A grid-based, PRMS watershed model of the LBCD has been created within ArcGIS 10, and physical parameters have been estimated at a spatial resolution of 100m. Simulation results will be available soon. Snow cover is expected to decrease and peak runoff to occur earlier in the spring, resulting in increased runoff, decreased infiltration/recharge, decreased baseflows, and decreased evapo-transpiration.

  5. 78 FR 76969 - Wright Brothers Day, 2013

    Science.gov (United States)

    2013-12-19

    ... boundaries of human imagination and paving the way for over a century of innovation. On Wright Brothers Day... Top, we are raising standards and making STEM education a priority. Last year, we announced plans to...

  6. Cerebrotendinous xanthomatosis: report of two Brazilian brothers.

    NARCIS (Netherlands)

    Lange, M.C.; Zetola, V.F.; Teive, H.; Scola, R.H.; Trentin, A.P.; Zavala, J.A.; Pereira, E.R.; Raskin, S.; Werneck, L.C.; Sistermans, E.A.

    2004-01-01

    Cerebrotendinous xanthomatosis is a treatable rare autossomal recessive disease characterized by lipid storage secondary to a sterol 27-hydroxylase deficiency in the formation of cholic and chenodeoxycholic acids. We describe two Brazilian brothers with cognitive impairement and chronic diarrhea.

  7. Minimal duality breaking in the Kallen-Lehman approach to 3D Ising model: A numerical test

    International Nuclear Information System (INIS)

    Astorino, Marco; Canfora, Fabrizio; Martinez, Cristian; Parisi, Luca

    2008-01-01

    A Kallen-Lehman approach to 3D Ising model is analyzed numerically both at low and high temperatures. It is shown that, even assuming a minimal duality breaking, one can fix three parameters of the model to get a very good agreement with the Monte Carlo results at high temperatures. With the same parameters the agreement is satisfactory both at low and near critical temperatures. How to improve the agreement with Monte Carlo results by introducing a more general duality breaking is shortly discussed

  8. Simple bone cysts of two brothers

    Energy Technology Data Exchange (ETDEWEB)

    An, Seo Young; An, Chang Hyeon; Choi, Karp Shik [Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyungpook National University, Daegu (Korea, Republic of)

    2008-09-15

    17-year-old and 14-year-old brothers were referred for evaluation of the cystic lesions on the mandibular anterior area with no symptoms. Neither their mother nor the brothers could recall any past trauma to those areas. Panoramic and intraoral radiographs revealed moderately defined cystic lesions on their mandibular anterior areas. Biopsies on both lesions revealed simple bone cysts. Hereditary cause or familial history of simple bone cysts could not be found in literature review. This case may have been a coincidence. However, further investigation is needed to find the cause of simple bone cysts occurring in patients those are closely related.

  9. Simple bone cysts of two brothers

    International Nuclear Information System (INIS)

    An, Seo Young; An, Chang Hyeon; Choi, Karp Shik

    2008-01-01

    17-year-old and 14-year-old brothers were referred for evaluation of the cystic lesions on the mandibular anterior area with no symptoms. Neither their mother nor the brothers could recall any past trauma to those areas. Panoramic and intraoral radiographs revealed moderately defined cystic lesions on their mandibular anterior areas. Biopsies on both lesions revealed simple bone cysts. Hereditary cause or familial history of simple bone cysts could not be found in literature review. This case may have been a coincidence. However, further investigation is needed to find the cause of simple bone cysts occurring in patients those are closely related.

  10. The Wright Brothers and their First Flight

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 12. The Wright Brothers and their First Flight. O N Ramesh. Article-in-a-Box Volume 8 Issue 12 December 2003 pp 3-4. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/008/12/0003-0004 ...

  11. The Wright Brothers and their First Flight

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 12. The Wright Brothers and their First Flight. O N Ramesh. Article-in-a-Box Volume 8 Issue 12 December 2003 pp 3-4. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/008/12/0003-0004 ...

  12. Anatomical Study of Somatic Embryogenesis in Glycine max (L. Merrill

    Directory of Open Access Journals (Sweden)

    Juliana Aparecida Fernando

    2002-09-01

    Full Text Available A comparative anatomical analysis of somatic embryogenesis in two soybean (Glycine max (L. Merrill genotypes was carried out. The somatic embryos were originated from cotyledonary explants obtained from immature zygotic embryos. The medium used for somatic embryogenesis induction was Murashige and Skoog, 1962, salts and Gamborg et al., 1968, vitamins (MSB supplemented with 0.8 mg.L-1 of 2,4-D for genotype PI 123439 and 40 mg.L-1 of 2,4-D for ‘Williams 82’. Globular structures, constituted by meristematic cells, originated from subepidermal cell divisions of the cotyledonary mesophyll. In PI 123439, the globular structures presented tracheary differentiation among meristematic cells and they could follow distinct morphogenetic process depending on their location along the explant. For ‘Williams 82’ it was observed globular structures along the cotyledonary explant surface. They gave rise to somatic embryos. These embryos showed different morphologies and they were classified based on their shape and number of cotyledons. The ability of these morphological types to convert to plantlets was discussed.Realizou-se uma análise anatômica comparativa da embriogênese somática em dois genótipos de soja (Glycine max (L. Merrill. Os embriões somáticos foram obtidos a partir de explantes cotiledonares excisados de embriões zigóticos imaturos do genótipo PI 123439, adaptado às condições tropicais, e ‘Williams 82’. O meio utilizado para indução da embriogênese somática constituiu-se de sais de Murashige e Skoog,1962, e vitaminas de Gamborg et al., 1968 (MSB suplementado com 0,8 mg.L-1 de 2,4-D (PI 123439 e 40 mg.L-1 (‘Williams 82’. Estruturas globulares originaram-se a partir de divisões celulares nas camadas subepidérmicas do mesofilo cotiledonar e foram constituídas por células meristemáticas. No genótipo PI 123439, as estruturas globulares apresentaram diferenciação traqueal entre as células meristemáticas e

  13. Drs. Smith Brothers: dental surgeons of Calcutta.

    Science.gov (United States)

    Sanjeev, Kumar

    2014-01-01

    During the British raj, India attracted dental practitioners from all over the world who set up practices in the Presidency towns of Calcutta, Bombay, Madras and Bangalore. Lured by the abundant opportunity to make good money, these mercenary but courageous dentists counted Viceroys, Indian royalty and political leaders amongst their clients. Some, like the famous American Smith Brothers of Calcutta, were sought after even by the rulers of neighboring countries. Dr. Mark Smith's hazardous visit to the Amir of Afghanistan made worldwide headlines more than 100 years ago for the fabulous fee he was paid for the dental treatment. This paper briefly describes the exploits and experiences of the Smith brothers while in India.

  14. Human radiation studies: Remembering the early years. Oral history of Merril Eisenbud, January 26, 1995

    International Nuclear Information System (INIS)

    1995-05-01

    Merril Eisenbud was interviewed on January 26, 1995 by representatives of the US DOE Office of Human Radiation Experiments. Following a brief biographical sketch, Mr. Eisenbud relates his remembrances as the AEC's first industrial hygienist, the setting up of AEC's Health and Safety Laboratory, monitoring radioactive fallout, and use or exposure of humans to radiation

  15. Application of Merrill's First Principles of Instruction in a Museum Education Context

    Science.gov (United States)

    Nelson, Kari Ross

    2015-01-01

    In an effort to support a solid grounding in educational theory within the field of museum education, three texts considered essential reading for museum educators were surveyed for correlations with Merrill's First Principles of Instruction, an influential work in the field of instructional design. Each of five First Principles were found to be…

  16. Teach Social Studies Concepts to First Grade Students? Research on the Merrill and Tennyson Model.

    Science.gov (United States)

    McKinney, C. Warren; And Others

    1982-01-01

    Describes a model for teaching social studies concepts developed by Merrill and Tennyson and presents findings from a study which examined its effectiveness. The model differs from many in that it is deductive, and each of its components is grounded in research. (RM)

  17. Partial DAZ deletions in a family with five infertile brothers

    NARCIS (Netherlands)

    Gianotten, Judith; Hoffer, Mariëtte J. V.; de Vries, Jan W. A.; Leschot, Nico J.; Gerris, Jan; van der Veen, Fulco

    2003-01-01

    Objective: To study the genetic cause of infertility in a family with five infertile brothers. Design: Case report. Setting: Center for reproductive medicine at a university medical center. Patient(s): Five brothers presenting with primary infertility due to severely impaired spermatogenesis; also,

  18. Homosexuality in men and number of older brothers.

    Science.gov (United States)

    Blanchard, R; Bogaert, A F

    1996-01-01

    This study investigated whether homosexual men have a higher mean birth order than heterosexual men primarily because they have more older brothers or because they have more older siblings of both sexes. For the main analyses, 302 heterosexual men were individually matched on year of birth with an equal number of heterosexual men. Each completed a self-administered, anonymous questionnaire concerning family background and other biodemographic information. Logistic regression analysis showed that homosexuality was positively correlated with the proband's number of older brothers but not with older sisters, younger brothers, younger sisters, or parental age at the time of the proband's birth. Each additional older brother increased the odds of homosexuality by 33%. These results restrict the range of possible theories of the birth order phenomenon to those that can explain not only why older brothers increase the probability of homosexuality in later-born males but also why older sisters neither enhance this effect nor counteract it.

  19. Neurological and architectural sinuosities: the Niemeyer brothers.

    Science.gov (United States)

    Cavalcanti, Daniel D; Guasti, José Antonio D; Preul, Mark C

    2010-11-01

    In a family of 7 siblings in Rio de Janeiro, Brazil, 2 of the most remarkable national personalities decided to follow different fields at the beginning of the 20th century. Their life's work would, however, intersect in at least 2 respects: the quest for innovation and a passion for sinuosity. The achievements of Paulo and Oscar Niemeyer are landmarks in the history of neurosurgery and architecture in Brazil. Among his many innovations in neurosurgery, Paulo Niemeyer first described the transventricular amygdalohippocampectomy in 1957 and introduced the operating microscope to neurosurgery in Brazil in 1971. His brother Oscar became a world-renowned representative of the modern architecture movement, sculpting graceful curves from concrete.

  20. A feasibility study in adapting Shamos Bickel and Hodges Lehman estimator into T-Method for normalization

    Science.gov (United States)

    Harudin, N.; Jamaludin, K. R.; Muhtazaruddin, M. Nabil; Ramlie, F.; Muhamad, Wan Zuki Azman Wan

    2018-03-01

    T-Method is one of the techniques governed under Mahalanobis Taguchi System that developed specifically for multivariate data predictions. Prediction using T-Method is always possible even with very limited sample size. The user of T-Method required to clearly understanding the population data trend since this method is not considering the effect of outliers within it. Outliers may cause apparent non-normality and the entire classical methods breakdown. There exist robust parameter estimate that provide satisfactory results when the data contain outliers, as well as when the data are free of them. The robust parameter estimates of location and scale measure called Shamos Bickel (SB) and Hodges Lehman (HL) which are used as a comparable method to calculate the mean and standard deviation of classical statistic is part of it. Embedding these into T-Method normalize stage feasibly help in enhancing the accuracy of the T-Method as well as analysing the robustness of T-method itself. However, the result of higher sample size case study shows that T-method is having lowest average error percentages (3.09%) on data with extreme outliers. HL and SB is having lowest error percentages (4.67%) for data without extreme outliers with minimum error differences compared to T-Method. The error percentages prediction trend is vice versa for lower sample size case study. The result shows that with minimum sample size, which outliers always be at low risk, T-Method is much better on that, while higher sample size with extreme outliers, T-Method as well show better prediction compared to others. For the case studies conducted in this research, it shows that normalization of T-Method is showing satisfactory results and it is not feasible to adapt HL and SB or normal mean and standard deviation into it since it’s only provide minimum effect of percentages errors. Normalization using T-method is still considered having lower risk towards outlier’s effect.

  1. Ozonation of Indigo Carmine Enhanced by Fe/Pimenta dioica L. Merrill Particles

    Directory of Open Access Journals (Sweden)

    Teresa Torres-Blancas

    2015-01-01

    Full Text Available Green synthesis of metallic particles has become an economic way to improve and protect the environment by decreasing the use of toxic chemicals and eliminating dyes. The synthesis of metal particles is gaining more importance due to its simplicity, rapid rate of synthesis of particles, and environmentally friendly. The present work aims to report a novel and environmentally friendly method for the synthesis of iron particles using deoiled Pimenta dioica L. Merrill husk as support. The indigo carmine removal efficiency by ozonation and catalyzed ozonation is also presented. Synthesized materials were characterized by N2 physisorption and scanning electron microscopy (SEM/EDS. By UV-Vis spectrophotometry the removal efficiency of indigo carmine was found to be nearly 100% after only 20 minutes of treatment under pH 3 and with a catalyst loading of 1000 mgL−1. Analytical techniques such as determination of the total organic carbon content (TOC and chemical oxygen demand (COD showed that iron particles supported on deoiled Pimenta dioica L. Merrill husk can be efficiently employed to degrade indigo carmine and achieved a partial mineralization (conversion to CO2 and H2O of the molecule. From the results can be inferred that the prepared biocomposite increases the hydroxyl radicals generation.

  2. Protective effect of Lannea coromandelica Houtt. Merrill. against three common pathogens

    Directory of Open Access Journals (Sweden)

    Rupinder Kaur

    2013-01-01

    Full Text Available Background: Ayurvedic text reports suggested Lannea coromandelica is used in various microbial origin disorders like dysentery, sore eyes and leprosy, genital wounds. Objective: The present study was designed to investigate the antimicrobial effect of L. coromandelica Houtt. Merrill. (Anacardiaceae on microbes which cause female reproductive tract infection. Materials and Methods: Ethanolic and aqueous bark extract (Ext. of L. coromandelica were screened against strains of Streptococcus pyogens, Staphylococcus aureus, and Candida albicans. Antimicrobial assay had been done with agar well diffusion method. Results: Ethanolic extracts [100% (16 mg, 75% (12 mg and 50% (8 mg] of L. coromandelica exhibited zone of inhibition (ZI 19.21 mm, 18.45 mm, 16.41 mm and 18.12 mm, 17.35 mm, 16.35 mm against S. aureus and S. pyogens, respectively. However, only 100% and 75% ethanolic extract showed (ZI-19.18 mm, 16.29 mm activity against C. albicans. Nevertheless, aqueous extract (100% showed higher antifungal activity (ZI-16.97 mm. Ciprofloxacin and amphotericin B were used as a standard drugs in the present study. Conclusion: The results demonstrated that L. coromandelica Houtt. Merrill. have antibacterial activity against S. pyogens, S. aureus and antifungal property against C. albicans. Our findings corroborate the ethnobotanical use of L. coromandelica in traditional medicine system (Ayurveda of India.

  3. Effect of gamma irradiation on microbial load, physicochemical and sensory characteristics of soybeans (Glycine max L. Merrill)

    Science.gov (United States)

    Gamma irradiation is highly effective in inactivating microorganisms in various foods and offers a safe alternative method of food decontamination. In the present study, soybeans (Glycine max L. Merrill) were treated with 0, 1.0, 3.0, 5.0 and 10.0 KGy of gamma irradiation. Microbial populations on s...

  4. Environmental behaviour of radioactivity from Chernobyl: Brothers Water study

    International Nuclear Information System (INIS)

    Bonnett, P.J.P.; Appleby, P.G.; Oldfield, F.; Haworth, E.Y.; Hilton, J.; Davison, W.

    1992-01-01

    A study has been carried out to examine the short term behaviour of Chernobyl derived radionuclides together with the longer term patterns of transport of weapons fallout derived 137 Cs first studied on the Brothers Water catchment in the English Lake District in the 1970's. Chernobyl derived radiocaesium is observable in the soils and lake sediments of the catchment. 210 Pb dating and diatom analysis were used to confirm that the lake sediments sampled were undisturbed. A simple box model is used to estimate radionuclide inventories in Brothers Water Lake sediments. Estimates derived using this model are reasonably consistent with estimates obtained from a variety of other sources. (author)

  5. 20 CFR 410.214 - Conditions of entitlement; parent, brother, or sister.

    Science.gov (United States)

    2010-04-01

    ... entitlement to brother's benefits may be established for any month before January 1973, based on a disability... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Conditions of entitlement; parent, brother...; Duration of Entitlement; Filing of Claims and Evidence § 410.214 Conditions of entitlement; parent, brother...

  6. Big Brother gør sit indtog

    DEFF Research Database (Denmark)

    Moeslund, Thomas B.

    2009-01-01

    På grund af frygten for terror er vi i dag parate til at acceptere en grad af overvågning, der før i tiden gav mindelser om George Orwells dystopi 1984. Teknisk er der dog betydelige udfordringer i at få IT-systemerne til at opføre sig som Big Brother. Udgivelsesdato: December...

  7. Freud on Brothers and Sisters: A Neglected Topic

    Science.gov (United States)

    Sherwin-White, Susan

    2007-01-01

    This paper explores Freud's developing thought on brothers and sisters, and their importance in his psychoanalytical writings and clinical work. Freud's work on sibling psychology has been seriously undervalued. This paper aims to give due recognition to Freud's work in this area. (Contains 1 note.)

  8. Propaganda in Warner Brothers World War II Cartoons.

    Science.gov (United States)

    Machowski, James Stanley; Brown, James William

    To examine the role of the animated cartoon in propaganda associated with World War II, 194 of 262 cartoons produced for theatrical release by Warner Brothers, Inc., from 1939 to 1946 were analyzed. Propaganda content was determined by the number and nature of symbols used and the cartoon's "attitudes" toward these symbols. An analysis…

  9. Commissioner for Inland Revenue V Lever Brothers and Unilever Ltd

    African Journals Online (AJOL)

    Lever Brothers, the South African tax case that formed the basis of this research, was concerned with determining the source of interest income. In its time, this was one of the landmark cases and established tax principles that were valid for 54 years, until superseded by changes to legislation. The research presented a ...

  10. Commissioner for Inland Revenue v Lever Brothers and Unilever Ltd

    African Journals Online (AJOL)

    kirstam

    21Key words: Lever Brothers and Unilever; South African income tax; source of income; interest; the “practical man”; the .... facilities, and he housed his employees in a model village of well-built homes on the factory site. ... be cancelled and any excess of the value of the shares over the debt would be adjusted by a money.

  11. Paternity testing in case of brother-sister incest.

    Science.gov (United States)

    Macan, Marijana; Uvodić, Petra; Botica, Vladimir

    2003-06-01

    We performed a paternity test in a case of incest between brother and sister. DNA from blood samples of the alleged parents and their two children was obtained with Chelex DNA extraction method and quantified with Applied Biosystems QuantiBlot quantitation kit. Polymerase chain reaction (PCR) amplification of DNA samples was performed with AmpFlSTR SGM Plus PCR amplification kit and GenePrint PowerPlex PCR amplification kit. The amplified products were separated and detected by using the Perkin Elmer's ABI PRISM trade mark 310 Genetic Analyser. DNA and data analysis of 17 loci and Amelogenin confirmed the suspicion of brother-sister incest. Since both children had inherited all of the obligate alleles from the alleged father, we could confirm with certainty of 99.999999% that the oldest brother in the family was the biological father of both children. Calculated data showed that even in a case of brother-sister incest, paternity could be proved by the analysis of Amelogenin and 17 DNA loci.

  12. Five Martyr Brothers. First Polish hermits and their worship

    Directory of Open Access Journals (Sweden)

    Kinga Blaschke

    2016-12-01

    Full Text Available Brothers Benedict and John, students of Romuald, came to Poland at the invitation of Otto III to convert pagans. Soon the Italian hermits were joined by Polish brothers Isaac and Matthew, who helped them in learning the Slavic language. The hermits, as well as Christinus, well killed in 1003 by thugs who wanted to steal money given by Duke Boleslav to an expedition to Rome, which was aimed at obtaining papal consent for conducting missionary work. Although the hermits died as victims of a robbery, killed by fellow Christians, the pope canonized them as martyrs. Their lives are relatively well-documented: the earliest and the most credible story of the five brothers by Bruno of Querfurt was written as early as five years after their death, although remained unknown until 1883. Another early account is the life of St. Romuald by Piotr Damiani of 1041. The martyrs have been also associated with yet another mysterious work – a gravestone unearthed in 1959 at the external wall of the north Roman apse of the Gniezno Cathedral, considered by most researchers the oldest epigraphic item on the Polish soil. However, the identification of the warriors mentioned in the inscription with 11th century martyrs raises many doubts. The article discusses the above matters, as well as the subject of the development of the worship of the martyr brothers.

  13. Review: Barbara Merril & Linden West (2009. Using Biographical Methods in Social Research

    Directory of Open Access Journals (Sweden)

    Vanessa Garcia Diaz

    2011-11-01

    Full Text Available The return of the subject in the social sciences reflects growing interest in the study of subjectivity. This refers to opportunities for individuals to make meaning of their lives within the institutions of society. MERRIL and WEST’s text serves as a reference for using biographical methods, as well as a reflection on the methodological and ethical issues inherent in doing this type of research.  This review examines the relationship between the book's content and its formal characteristics (didactic style, writing style and its interdisciplinary nature. This review also focuses on the advantages that this textbook may offer if used in  qualitative research courses in general and, specifically, in courses dealing with biographical research methods. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1201104

  14. Response of antioxidative enzymes to arsenic-induced phytotoxicity in leaves of a medicinal daisy, Wedelia chinensis Merrill

    OpenAIRE

    Talukdar, Tulika; Talukdar, Dibyendu

    2013-01-01

    Background: Wedelia chinensis Merrill (Asteraceae) is a medicinally important herb, grown abundantly in soils contaminated with heavy metals, including toxic metalloid arsenic (As). The leaves have immense significance in treatment of various ailments. Objective: The present study was undertaken to ascertain whether the edible/usable parts experience oxidative stress in the form of membrane damage during As exposure or not. Materials and Methods: Responses of seven antioxidant enzymes were st...

  15. The comparison of family types in fairy tales by brothers Grimm and H. C. Andersen

    OpenAIRE

    Šček, Marjeta

    2014-01-01

    The present thesis entitled The Comparison of Family Types in Fairy Tales by Brothers Grimm and H. C. Andersen consists of two parts: the theoretical and the empirical part. The first part is a brief summary of opuses and biographies of Jacob and Wilhelm Grimm and Hans Christian Andersen, followed by a section describing several different definitions of families and family types. The second part is an analysis of ten fairy tales by brothers Grimm: The Frog King, or Iron Henry, Little Brother ...

  16. Neoteric trends in tissue culture-mediated biotechnology of Indian ipecac [Tylophora indica (Burm. f.) Merrill].

    Science.gov (United States)

    Gantait, Saikat; Kundu, Suprabuddha

    2017-07-01

    Tylophora indica (Burm. f.) Merrill, an ethno-pharmacologically important perennial climber of Asclepiadaceae, is commonly known as Antamul or Indian ipecac. It is essentially accredited for its medicinal properties owing to its wide range of alkaloids in the form of bioactive secondary metabolites, such as tylophorine, tylophorinine, and tylophorinidine. Accelerated mass propagation of Tylophora is challenging because of its reduced seed germination frequency that consequently headed the pursuit for efficient protocols on in vitro propagation for the large-scale regeneration, conservation as well as sustainable supply of quality propagules. Ample tissue culture-mediated biotechnological investigations have been carried out on this medicinal plant till date and several micropropagation protocols have been standardized as well. The present review compares between several typical methods as well as factors, involving on direct and indirect organogenesis of Tylophora along with various up-to-date and modified techniques such as somatic embryogenesis, protoplast culture, synthetic seed production, genetic transformation, and in vitro interventions for the secondary metabolite production that have been reported in last two decades. This compilation will allow assessing the achievements and trends of Tylophora research so far, as well as will advance the research more rapidly, since many aspects, basic and applied, have yet to be explored.

  17. Growth and quality of soybean sprouts (Glycine max L. Merrill) as affected by gamma irradiation

    International Nuclear Information System (INIS)

    Yun, Juan; Li, Xihong; Fan, Xuetong; Li, Weili; Jiang, Yuqian

    2013-01-01

    In this study, soybean seeds and sprouts (Glycine max L. Merrill) were exposed to radiation doses up to 3.0 kGy. The irradiated and non-irradiated seeds were germinated, and then germination rate, sprouts length, vitamin C content, antioxidants and visual and olfactory quality were determined after irradiation. Results indicated that there was no significant difference in the germination rate and sprouts length between the control and 0.3 kGy treated soybeans, however, the reductions in sprouts length of the 1.0 kGy and 3.0 kGy treated samples were quite significant with reductions of 20.4% and 58.8%, respectively. Irradiated sprouts had similar visual and olfactory quality as the non-irradiated one. Therefore, irradiation of seeds alone would have limited value in terms of commercial use due to reduced germination and length of sprouts. However, irradiation of sprouts at doses up to 3.0 kGy was feasible to enhance microbial safety of sprouts. - Highlights: ► Investigated the germination rate and the sprouts length after irradiation. ► Indicated the effect of irradiation on the antioxidants of the soybean sprouts. ► Evaluated the visual and olfactory quality of irradiated samples.

  18. Isoflavones profiling of soybean [Glycine max (L.) Merrill] germplasms and their correlations with metabolic pathways.

    Science.gov (United States)

    Kim, Jae Kwang; Kim, Eun-Hye; Park, Inmyoung; Yu, Bo-Ra; Lim, Jung Dae; Lee, Young-Sang; Lee, Joo-Hyun; Kim, Seung-Hyun; Chung, Ill-Min

    2014-06-15

    The isoflavone diversity (44 varieties) of the soybean, Glycine max (L.) Merrill, from China, Japan, and Korea was examined by high-performance liquid chromatography. The profiles of 12 isoflavones identified from the grains were subjected to data-mining processes, including partial least-squares discriminant analysis (PLS-DA), Pearson's correlation analysis, and hierarchical clustering analysis (HCA). Although PLS-DA did not reveal significant differences among extracts of soybean from 3 countries, the results clearly show that the variation between varieties was low. The CS02554 variety was separate from the others in the first 2 principal components of PLS-DA. HCA of these phytochemicals resulted in clusters derived from closely related biochemical pathways. Daidzin, genistin, and glycitin contents were significantly correlated with their respective malonyl glycoside contents. Daidzein content correlated positively with genistein content (r=0.8189, P<0.0001). The CS02554 variety appears to be a good candidate for future breeding programs, as it contains high levels of isoflavone compounds. These results demonstrate the use of metabolite profiling combined with chemometrics as a tool for assessing the quality of food and identifying metabolic links in biological systems. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. HERITABILITAS, NISBAH POTENSI, DAN HETEROSIS KETAHANAN KEDELAI (Glycine max [L.] Merrill TERHADAP SOYBEAN MOSAIC VIRUS

    Directory of Open Access Journals (Sweden)

    Nyimas Sa’diyah

    2016-10-01

    Full Text Available Heritability, potential ratio, and heterosis of soybean (Glycine max [L.] Merrill resistance to soybean mosaic virus. The use of soybean cultivars with resistance to SMV is a way for controlling soybean mosaic disease. The objective of this research was to estimate the disease severity, the narrow sense heritability, potential ratio and heterosis of resistance character and number of pithy pods, number of healthy seeds, and healthy seeds weight per plant of ten F1 populations of soybean crossing result to SMV infection. The experiment was arranged in a randomized complete block design in two replications. Observed characters were disease severity, number of pithy pods, number of healthy seeds, and healthy seeds weight per plant. The result of this research showed that 1 the crossing combinations those which were resistant to SMV (lower disease severity were Yellow Bean x Tanggamus, Tanggamus x Orba, and Tanggamus x Taichung, 2 the narrow sense heritability of disease severity was included in medium criteria, 3 number of pithy pods belonged to high criteria, and 4 number of healthy seeds and healthy seeds weight per plant were included in low criteria. The crossing combinations that had low estimation value of heterosis and heterobeltiosis of resistance to SMV infection were Yellow Bean x Taichung, Bean x Tanggamus and Tanggamus x B3570. Disease severity or resistance to SMV is influenced by genetic and environmental factors.

  20. Living with a brother or sister with epilepsy: siblings' experiences.

    Science.gov (United States)

    Hames, Annette; Appleton, Richard

    2009-12-01

    There is conflicting evidence about the impact of disability upon siblings, and very little research on the siblings of children with epilepsy. There is some evidence that siblings who have less accurate information exhibit more distress. The aim of this study was to assess siblings' response to having a brother or sister with epilepsy and to begin to develop information for them. Parents of children attending paediatric neurology outpatient departments were invited to participate in a pilot study. Parents who consented to take part were asked if they had previously received information for siblings. Parents and siblings participated in a semi-structured interview and siblings were also invited to submit a personal account of living with a brother or sister who had epilepsy. Twenty-five families with a child with epilepsy aged 2.5-15 years initially agreed to take part. None of the families stated that they had ever seen or received any information specifically for siblings. Fourteen siblings from the 25 families, aged 8-25 years, provided a personal account of what it was like living with a brother or sister with epilepsy. Siblings' accounts included both negative and positive feelings, and specifically feelings of care and love for their sibling. This initial study suggests that siblings of children with epilepsy have many positive but also early negative feelings. The results are limited by the size of the study, the fact that most siblings were older sisters, and the mean time since diagnosis was 6 years. Finally, it is hoped that the personal accounts collected in this study will be published for the benefit of other siblings of children with epilepsy.

  1. Laryngologist Leon Zamenhof--brother of Dr. Esperanto.

    Science.gov (United States)

    Wincewicz, Andrzej; Sulkowska, Mariola; Musiatowicz, Marcin; Sulkowski, Stanislaw

    2009-06-01

    To reconstruct the biography of the Polish otorhinolaryngologist Leon Zamenhof (1875-1934), a brother of Ludwik Zamenhof, who is famous for invention of the international language Esperanto. Biographical information was collected from pre-World War II resources. Zamenhof developed several important new forms of treatment to help the hearing impaired. Zamenhof was especially interested in the education of deaf children and the therapy necessary to facilitate their integration into society. His significant achievements were a phonetic method of therapy for the hearing impaired and an automatic device for ear insufflation that was considered indispensable in the management of pyorrhea. In addition, Zamenhof initiated various forms of social support among physicians within the medical community of Warsaw, Poland; made health care available to children with hearing impairments; and organized a Jewish school for deaf children. Zamenhof tried to change public attitudes toward deafness, working to promote the integration of the deaf into wider society. He also translated Polish literature into Esperanto. With similar aims to his brother Ludwik, Leon Zamenhof strived to enhance and broaden communication among people who could not hear and to persuade people to change their attitudes about deafness.

  2. Matching osteochondritis dissecans lesions in identical twin brothers.

    Science.gov (United States)

    Richie, Lucas B; Sytsma, Mark J

    2013-09-01

    Osteochondritis dissecans is a disorder of unknown etiology that can result in fragmentation of osteochondral surfaces, most commonly of the knee, shoulder, elbow, and ankle. This may lead to sequelae of pain and an inability to participate in desired activities. Multiple theories exist as to the true cause of the disorder, but none have been fully proven. One such proposed etiology is genetic causation. Familial cases of osteochondritis dissecans are rare, yet these cases offer support to growing evidence that may support a genetic link. This article describes osteochondritis dissecans lesions of the femoral trochlea in monozygotic (identical) twins. Both twins presented with similar symptoms 1 year apart. Neither twin had any clear inciting trauma. Magnetic resonance imaging revealed osteochondral lesions in similar positions of the lateral trochlear of the same knee in both brothers. Osteochondral autograft transfer and tibial tubercle anteromedialization were performed on both patients. An identical postoperative protocol was followed, and recovery with full return to sport was comparable for the brothers. To the authors' knowledge, only 1 other case report exists of osteochondritis dissecans lesions in monozygotic twins. Although debate continues regarding the true etiology of this disorder, cases of identical twins presenting with a similar disease process are highly suggestive of a genetic component and may lead to early identification and treatment of these lesions. Continued research in the area of osteochondritis dissecans and its genetic basis is needed to completely understand this disorder. Copyright 2013, SLACK Incorporated.

  3. Identification and colonization of endophytic fungi from soybean (Glycine max (L. Merril under different environmental conditions

    Directory of Open Access Journals (Sweden)

    Ida Chapaval Pimentel

    2006-09-01

    Full Text Available A total of 297 endophytic fungi were isolated from 1728 leaf and stem fragments collected about twenty and forty days after germination from soybean (Glycine max (L. Merril plants grown in the field and a greenhouse. The fungi belonged to eight groups, six dematiaceous genera (Alternaria, Cladosporium, Chaetomium, Curvularia, Drechslera and Scopulariopsis and the non-dematiaceous genera Acremonium, Aspergillus, Colletotrichum, Fusarium, Paecilomyces and Penicillium along with some Mycelia sterilia.. There were qualitative and quantitative differences in the type and number of isolates obtained from greenhouse and field-grown plants, with more isolates being obtained from the latter. No difference was found in the number of fungi isolated from leaves and stems irrespective of where the plants was grown. For was field-grown plants, the number of isolates decreased as the plants aged and more fungi were found in tissues near the soil, while for greenhouse-grown plants the number of isolates increased as the plants aged but in this case no more fungi were isolated from those tissues nearer the soil. These results could have biotechnological relevance for the biological control of pests or plant growth promotion.A partir de 1728 fragmentos de hastes e folhas de soja (Glycine max (L. Merril. provenientes de plantas do campo e de casa de vegetação, coletadas cerca de 20 e 40 dias após a germinação das sementes, 297 fungos endofíticos foram isolados. Os gêneros encontrados foram: Alternaria, Cladosporium, Curvularia, Chaetomium, Scopulariopsis, Drechslera (todos dematiáceos além de Colletotrichum, Fusarium, Acremonium, Aspergillus, Penicillium, Paecilomyces e Mycelia sterilia. Foram detectadas diferenças qualitativas e quantitativas entre os isolados, em relação a micobiota de hospedeiros provenientes do campo e de casa de vegetação com maior frequência de fungos isolados de plantas no campo em comparação com as de casa de vegeta

  4. Utilization of the biorreactor of imersion by bubbles at the micropropagation of Ananas comosus L. Merril

    Directory of Open Access Journals (Sweden)

    Gessiel Newton Scheidt

    2009-11-01

    Full Text Available The research for new techniques of in vitro cultivation is being object of many studies around the world, in order to optimize and decrease production costs of seedlings with agronomical interest. The main goal of this work was to compare different systems of in vitro cultivations using Ananas comosus L. Merril. So, the in vitro growth of the plantlets was promoted in two different bioreactors: Bioreactor of Immersion by Bubbles (B.I.B.® and the Reactor of Temporary Immersion (R.I.T.A.® with immersion cycle every 2 hours for 15 minutes and the traditional system in flasks with 200 mL. All cultivation systems used the MS liquid nutritive solution, supplemented with BAP (1 mgL-1, ANA (0.25 mgL-1, sucrose (30 gL-1 and Tween 20® (0.5 µL. The pH was adjusted to 5.8 and sterilized at 120°C for 15 minutes. The cultures were kept into a growth room during 30 days, with controlled temperature of 25±2°C, under white cold light (46.8 µmol.m-2.s-1, with photoperiod of 16 hours. The experimental design used was randomized, with three treatments, three repetitions and ten plants each stage. Among the evaluated systems, the BIB® presented the best results for the tested variables, mainly the total number of shoots, being 2.3 e 3.1 times superior when compared with the system R.I.T.A.® and the traditional consecutively. So the system of immersion by bubbles turns into an effective equipment to produce seedlings of pineapple in large scale.A busca por novas técnicas de cultivo in vitro vem sendo amplamente estudadas, visando otimizar e baixar o custo de produção das mudas que tenham interesse agronômico. O objetivo deste trabalho foi comparar diferentes sistemas de cultivo in vitro de Ananas comosus L. Merril. Para tanto, o crescimento in vitro de plântulas foi promovido em sistemas de biorreatores (B.I.B.® e R.I.T.A.® com ciclo de imersão a cada 2 horas por 15 minutos e o sistema tradicional em frascos de 200 mL. Em todos os sistemas de

  5. The Perceptions and Experiences of Adolescent Siblings Who Have a Brother with Autism Spectrum Disorder

    Science.gov (United States)

    Petalas, Michael A.; Hastings, Richard P.; Nash, Susie; Reilly, Deirdre; Dowey, Alan

    2012-01-01

    Background: There is a dearth of research on the perspectives of adolescent siblings growing up with a brother or sister with an autism spectrum disorder (ASD). Method: Semistructured interviews were used to elicit the perceptions and experiences of 12 typically developing adolescents with a brother with an ASD. Interpretative phenomenological…

  6. Living with a Brother Who Has an Autism Spectrum Disorder: A Sister's Perspective

    Science.gov (United States)

    Connell, Zara O.; Halloran, Maeve O.; Doody, Owen

    2016-01-01

    People with Autism Spectrum Disorder (ASD) are born into families and influence family functioning both positively and negatively. One of the most enduring relationships a person with ASD will have is their relationship with a brother or sister. Services for people with ASD should provide effective support to families, which include brothers,…

  7. "Southern Pop Culture and the Literary Tradition in O Brother, Where Art Thou?"

    DEFF Research Database (Denmark)

    Bjerre, Thomas Ærvold

    2009-01-01

      This essay discusses the Coen brothers movie O Brother, Where Art Thou? (2000). Rather than reading the movie as a modern retelling of The Odyssey, as most critics have done, it is read within a context of Southern literature and history. The essay points out and discusses the many references...

  8. Mothers' differential treatment of adolescent siblings: predicting college attendance of sisters versus brothers.

    Science.gov (United States)

    Bissell-Havran, Joanna M; Loken, Eric; McHale, Susan M

    2012-10-01

    Current estimates suggest that by 2015, 60% of college students will be women, a change since 1970 when 59% were men. We investigated family dynamics that might explain the growing gender gap in college attendance, focusing on an ethnically diverse sample of 522 mixed sex sibling dyads from the National Longitudinal Study of Adolescent Health. We examined whether the difference between sisters' and brothers' reports of their mothers' expectations for, and involvement in, their education during adolescence predicted their differential odds of college attendance seven years later. Sisters were more likely than brothers to attend college, and this gap was more pronounced among non-Whites and non-Asians. Sisters also had higher grades in school than their brothers. Although there were no gender differences overall in maternal educational expectations or involvement, brothers reported greater maternal involvement than sisters in non-White and non-Asian families. After controlling for family background factors, the average of siblings' reports of maternal treatment, and differences between siblings' grades, the results revealed that as sisters reported greater maternal educational expectations than their brothers, it became more likely that only the sister rather than only the brother in the family attended college. The difference between brothers' and sisters' reports of their mothers' educational involvement and their odds of attending college showed the same pattern of association but was not statistically significant. These results suggest that within-family social comparisons may play a role in sisters' and brothers' choices about attending college.

  9. Potential Effects of a Warming Climate on Water Resources within the Lehman and Baker Creek Drainages, Great Basin National Park, Nevada

    Science.gov (United States)

    Volk, John M.

    Warming trends in near-surface air temperature across the Southwestern U.S. have been observed over the last century and are projected to continue over the 21st century. This warming trend will result in decreased snowpack and earlier snowmelt in mountainous basins throughout the West; however, predictions of future precipitation in the Southwest are much more uncertain among global climate models (GCMs). In this study, the objective was to quantitatively evaluate the impacts of projected warming on streamflow in the Lehman and Baker Creek drainages. The drainages are located in Great Basin National Park that encompasses the highest elevations in the southern part of the Snake Range in eastern Nevada. The Precipitation-Runoff Modeling System (PRMS) was used to evaluate impacts of warming on streamflow. Calibration and validation periods had total errors between 0.6 and 12 percent in simulated streamflow. Daily maximum and minimum temperatures for a future 90-year period were used in the model to evaluate how warming temperatures may affect streamflow. Daily temperatures were statistically downscaled and bias corrected using daily projections from the National Center for Atmospheric Research Community Climate System Model 4.0 for four representative greenhouse gas concentration trajectories. A 30-year record of historical precipitation was repeated three times over the 90-year simulation. Results from the 90-year simulation were divided into three 30-year periods (water years 2009--2038, 2039--2068, and 2069--2098) and were compared among the four greenhouse gas concentration trajectories such that volumes and variations in precipitation were identical and changes could be directly related to different projected warming temperatures. The study area was sensitive to small increases in temperature; results include shifts to earlier snowmelt timing for most warming trajectories from May to April with an increase in winter streamflow. For a temperature rise of 5.5°F by

  10. Isolated Penile Torsion in Brothers: A Case Report

    Directory of Open Access Journals (Sweden)

    Metin Gunduz

    2012-04-01

    Full Text Available Penile torsion can be congenital and associated with hypospadias and chordee, or can be acquired after circumcision. The incidence of isolated neonatal penile torsion was 1.7 to 27% in the literature. The majority were between 10 and deg; and 20 and deg;. Generally, torsion was to the left in cases. The techniques for correction of penile torsion described in the literature are penile de-gloving and reattaching of skin, resection of Buck's fascia incising the base of the penis and removing angular ellipses of corporeal tissue with subsequent plication of tunica, and dorsal dartos flap rotation in severe cases. In conclusion, penile torsion may be familial. Therefore, brothers should be examined carefully. The degloving and realignment technique is successful in isolated penile torsion. [Arch Clin Exp Surg 2012; 1(2.000: 122-124

  11. Brother Peter of Jesus at Purgatory: rewrites of a historiographyc passage

    Directory of Open Access Journals (Sweden)

    Joan Mahiques Climent

    2016-12-01

    Full Text Available The second volume of the Reforma de los descalzos (Madrid, 1655 of Brother Francis of St. Mary relates that Brother Peter of Jesus, while dying in Bellpuig because of the plague, appeared to a companion in Lleida to say he was in Purgatory. From different printed works and engravings published from 1681 to 1724, we study the relationship between texts and images representing this episode. We also edit two versions written by Brother John of St. Joseph (1642-1718, whose autographs are preserved in mss. 990 and 991 of the University of Barcelona Library.

  12. Floral biology and behavior of Africanized honeybees Apis mellifera in soybean (Glycine max L. Merril

    Directory of Open Access Journals (Sweden)

    Wainer César Chiari

    2005-05-01

    Full Text Available This research was carried out to evaluate the pollination by Africanized honeybees Apis mellifera, the floral biology and to observe the hoarding behavior in the soybean flowers (Glycine max Merril, var. BRS-133. The treatments were constituted of demarcated areas for free visitation of insects, covered areas by cages with a honeybee colony (A. mellifera and also covered areas by cage without insects visitation. All areas had 24 m² (4m x 6m. The soybean flowers stayed open for a larger time (82.82 ± 3.48 hours in covered area without honeybees. The stigma of the flowers was also more receptive (P=0.0021 in covered area without honeybees (87.3 ± 33.0% and at 10:42 o'clock was the schedule of greater receptivity. The pollen stayed viable in all treatments, the average was 99.60 ± 0.02%, which did not present differences among treatments. The percentage of abortion of the flowers was 82.91% in covered area without honeybees, this result was superior (P=0.0002 to the 52.66% and 53.95% of the treatments uncovered and covered with honeybees, respectively. Honeybees were responsible for 87.7% of the pollination accomplished by the insects. The medium amounts of total sugar and glucose measured in the nectar of the flowers were, 14.33 ± 0.96 mg/flower and 3.61 ± 0.36 mg/ flower, respectively, not showing differences (PEste experimento teve como objetivos avaliar a polinização realizada por abelhas Apis mellifera, estudar a biologia floral e observar o comportamento de coleta nas flores de soja (Glycine max L. Merril, variedade BRS-133 plantadas na região de Maringá-PR. Os tratamentos constituíram de áreas demarcadas de livre visitação por insetos, áreas cobertas por gaiolas, com uma colônia de abelhas (A. mellifera no seu interior e plantas também cobertas por gaiola que impedia a visitação por insetos. Todas as áreas possuíam 24 m² (4 m x 6 m. As flores de soja permaneceram abertas por um tempo maior (82,82 ± 3,48 horas no

  13. 20 CFR 410.340 - Determination of relationship; parent, brother, or sister.

    Science.gov (United States)

    2010-04-01

    ... domiciled (see § 410.392) at the time of his death would find, under the law they would apply in determining..., brother, or sister. Where, under such law, the individual does not bear the relationship to the miner of...

  14. Do brothers and sisters of siblings with intelectual disability need the support of social work?

    OpenAIRE

    Cardová, Michaela

    2007-01-01

    This thesis explores the experience and support needs of siblings with a brother or sister with intellectual disability. Through review of what is a quite limited literature and from original qualitative research, involving interviews with siblings, the author examines their social reality, focusing especially on their relationships with their disabled brother or sister and with the wider society. Particular attention is given to identifying to what extent the siblings' lives are influenced b...

  15. The Warner Brothers and Franklin Delano Roosevelt:Connections and Collaborations

    OpenAIRE

    Cohen, Harvey

    2013-01-01

    This working paper traces the history of the Warner brothers and their Hollywood film studio, from their hardscrabble beginnings to their famous championing of a "social realist" aesthetic in their motion pictures released during the 1920s and 1930s. The pre-presidential career of Franklin Delano Roosevelt is also featured and contrasted with that of the Warner Brothers, setting up a discussion of how the Warner Bros. Studio not only supported Roosevelt financially with fundraising events but...

  16. Desenvolvimento de Cerveja Artesanal com Acerola (Malpighia emarginata DC e Abacaxi (Ananas comosus L. Merril

    Directory of Open Access Journals (Sweden)

    L. I. F. Pinto

    2015-12-01

    Full Text Available A cerveja é a bebida alcoólica mais consumida no mundo. Estando bem relacionado com festividades e comemorações, porém essa bebida contém uma variedade de compostos bioativos, vitaminas e minerais, capazes de promover benefícios quando a sua ingestão é feita de maneira moderada. O mercado está a cada dia buscando produtos diferenciados e até exclusivos, surge assim o campo das cervejas artesanais. O objetivo deste trabalho foi desenvolver uma cerveja artesanal com acerola e abacaxi, trazendo uma nova alternativa ao nicho de mercado, além da associação ao aumento de suas características funcionais. O experimento foi conduzido no Laboratório de Cereais, Universidade Federal do Ceará – UFC, onde a cerveja foi produzida em escala laboratorial passando pelos processos de moagem do malte, mosturação, cozimento, decantação, filtração, fermentação, envase, maturação e primming, sendo adicionada a polpa de fruta em percentagem definidas por DIC, pasteurização e armazenamento. As amostras foram submetidas à análise físico-química, microbiológica e sensorial. Os resultados foram submetidos ao teste de normalidade, ao teste de média tukey e a ANOVA pelo software STATISTIC 10. A utilização das polpas de abacaxi e acerola como adjuntos no processamento da cerveja mostrou-se uma alternativa viável demostrada pelos resultados satisfatórios na avaliação sensorial, além de características físico-químicas de uma cerveja artesanal ácida/frutada. Development of craftbeer with Acerola (Malpighia emarginata DC and pineapple (Ananas comosus L. MerrilAbstract: The beer is the most consumed alcoholic beverage in the world. It is well associated with holidays and celebrations, but this beverage contains a variety of bioactive compounds, vitamins and minerals that promote benefits when its intake is made moderate manner. The market is every day looking for different and even unique products, thus arises the field of craft

  17. The Montgolfier Brothers and the Invention of Aviation

    Science.gov (United States)

    Moore, Charles B.

    The first hot air balloon ascension over Paris in September 1783 has been described so many times that it and its passengers—the sheep, the rooster, and the duck—have joined Benjamin Franklin and his kite in the folklore of our culture. Not so well known is the earlier history of ballooning; that the brothers Montgolfier had demonstrated their hot air balloons repeatedly for several months prior to the ascent over Paris; or that the physicist Charles, urged onward and financed by an enthusiast, Barthélemy Faujas de Saint-Fond, launched successfully the first fabric balloon filled with hydrogen over Paris more than 3 weeks prior to the memorable ascent of the sheep, and rooster, and the duck.For all of its well-documented detail, the book is readable and enjoyable. It is a well-written but complex book in which Professor Gillispie develops a number of subjects to recreate the era in perspective. The origins and the disposition of the Montgolfiers, the industry of the period, the idea of capturing heated air are all reported in detail. The attempts to obtain government funding and the promotional activities in Paris were forerunners of the modern techniques for obtaining support of research activities.

  18. Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype

    OpenAIRE

    Zhang, Yanliang; Liu, Yanhui; Li, Ya; Duan, Yong; Zhang, Keyun; Wang, Junwang; Dai, Yong

    2014-01-01

    Background We report on two brothers with a distinct syndromic phenotype and explore the potential pathogenic cause. Methods Cytogenetic tests and exome sequencing were performed on the two brothers and their parents. Variants detected by exome sequencing were validated by Sanger sequencing. Results The main phenotype of the two brothers included congenital language disorder, growth retardation, intellectual disability, difficulty in standing and walking, and urinary and fecal incontinence. T...

  19. Mortality and health-related habits in 900 Finnish former elite athletes and their brothers.

    Science.gov (United States)

    Kontro, Titta Katariina; Sarna, Seppo; Kaprio, Jaakko; Kujala, Urho M

    2018-01-01

    There is conflicting evidence on the associations between participation in vigorous sports, health habits, familial factors and subsequent mortality. We investigated all-cause mortality and health-related behaviour among former elite athletes and their brothers. The mortality of Finnish male former elite athletes, who had represented Finland between 1920 and 1965 (n=900) and their age-matched brothers (n=900), was followed from the time when athlete started an elite athlete career until 31 December 2015. The age-adjusted HRs were calculated by a paired Cox proportional hazards model. In 2001, surviving participants (n=199 athletes and n=199 age-matched brothers) reported their self-rated health (SRH), physical activity, alcohol consumption and smoking habits in the questionnaire. During the total follow-up period, 1296 deaths (72% of the cohort) occurred. The age-adjusted HRs for all-cause mortality in former athletes was 0.75 (95% CI 0.65 to 0.87, Psports and 72.2 years for power sports athletes, and 77.5, 73.7 and 72.2 years for their age-matched brothers, respectively. In 2001, compared with their brothers, former athletes smoked less (Pathletes are more physically active, smoke less, have better self-rated health and live longer than their brothers. Genetic differences between athletes and brothers, aerobic training for endurance elite sports and a healthier lifestyle may all contribute to reduced mortality. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  20. Brother of CDO (BOC) expression in equine articular cartilage.

    Science.gov (United States)

    Vanderman, K S; Tremblay, M; Zhu, W; Shimojo, M; Mienaltowski, M J; Coleman, S J; MacLeod, J N

    2011-04-01

    Brother of CDO (BOC) is a cell surface receptor that derives its name from the structurally related protein, cell adhesion molecule-related/down-regulated by oncogenes (CDO, sometimes CDON). High levels of BOC mRNA and protein expression have been described in embryonic tissues with active cell proliferation and ongoing cellular differentiation(1,2). A microarray-based screen of RNA isolated from 11 different adult equine tissues unexpectedly identified BOC as having an expression pattern restricted to articular cartilage. The objective of this study was to further investigate BOC expression in adult articular cartilage relative to other tissues. Both RT-qPCR and mRNA sequencing confirmed the microarray data. Steady state BOC mRNA levels in articular cartilage were substantially higher than in the other adult tissues tested, neonatal tendon, placenta, and whole embryo. The expression of BOC displayed a pattern of tissue specificity comparable to well established cartilage matrix protein biomarkers. BOC mRNA levels in articular cartilage increased with age, but were rapidly down-regulated when chondrocytes were enzymatically isolated from the cartilage matrix and expanded in monolayer culture. Relative expression patterns of CDO were broadly similar, but displayed lower fold change differences. A functional role in articular cartilage that involves Hedgehog signaling is suggested by the known binding affinity of BOC for all three Hedgehog ligands. These data also extend BOC and CDO biology to a post-mitotic and highly differentiated cell type within a mature tissue. Copyright © 2011 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

  1. Extreme right-handedness, older brothers, and sexual orientation in men.

    Science.gov (United States)

    Bogaert, Anthony F

    2007-01-01

    Two of the most consistent correlates of sexual orientation in men are handedness and fraternal birth order (i.e., number of older brothers). In the present study, the relationship among handedness, older brothers, and sexual orientation was studied in 4 samples of heterosexual and gay or bisexual men (N = 944). Unlike previous studies, which have only observed an increased rate of non-right-handedness in gay or bisexual men relative to heterosexual men, an elevated rate of extreme right-handedness was found in gay or bisexual men relative to heterosexual men. The results also demonstrated that older brothers moderate the relationship between handedness and sexual orientation. Specifically, older brothers increase the odds of being gay or bisexual in moderate right-handers only; in both non-right-handers and extreme right-handers, older brothers do not affect (or decrease) the odds of being gay or bisexual. The results have implications for an early neurodevelopmental origin to sexual orientation in men. (c) 2007 APA, all rights reserved.

  2. Evaluation of dredged material proposed for ocean disposal from South Brother Island Channel, New York

    Energy Technology Data Exchange (ETDEWEB)

    Barrows, E.S.; Gardiner, W.W.; Antrim, L.D.; Gruendell, B.D.; Word, J.Q.; Tokos, J.J.S. [Battelle Marine Sciences Laboratory, Sequim, Washington (United States)

    1996-09-01

    South Brother Island Channel was one of seven waterways that the US Army Crops of Engineers-New York District requested the Battelle/Marine Sciences Laboratory to sample and evaluate for dredging and disposal. Tests and analyses were conducted on South Brother Island Channel sediment core samples and evaluations were performed. The evaluation of proposed dredged material from South Brother Island Channel included bulk sediment chemical analyses, chemical analyses of site water and elutriate, water-column and benthic acute toxicity tests, and bioaccumulation studies. Individual sediment core samples collected from Souther Brother Island Channel were analyzed for grain size, moisture content, and total organic carbon. a composite sediment sample, representing the entire area proposed for dredging, was analyzed for bulk density, specific gravity, metals, chlorinated pesticides, polychlorinated biphenyl congers, polynuclear aromatic hydrocarbons, and 1,4- dichlorobenzene. Site water and elutriate water, prepared from the suspended-particle phase of South Brother Island Channel sediment, were analyzed for metals, pesticides, and PCBs.

  3. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers

    DEFF Research Database (Denmark)

    Bandak, M.; Jorgensen, N.; Juul, A.

    2017-01-01

    was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular...... cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III...

  4. Intrafamilial Sexual Abuse: Brother-Sister Incest Does Not Differ from Father-Daughter and Stepfather-Stepdaughter Incest.

    Science.gov (United States)

    Cyr, Mireille; Wright, John; McDuff, Pierre; Perron, Alain

    2002-01-01

    A study compared 72 girls (ages 5-16) sexually abused by brothers, fathers, or stepfathers. Results suggested few differences in characteristics of sexual abuse. However, penetration was much more frequent in the sibling incest group. More victims of fathers and brothers manifested clinically significant distress (90%), than stepfather victims…

  5. Inoculation with Bradyrhizobium japonicum enhances the organic and fatty acids content of soybean (Glycine max (L.) Merrill) seeds.

    Science.gov (United States)

    Silva, Luís R; Pereira, Maria J; Azevedo, Jessica; Mulas, Rebeca; Velazquez, Encarna; González-Andrés, Fernando; Valentão, Patrícia; Andrade, Paula B

    2013-12-15

    Soybean (Glycine max (L.) Merrill) is one of the most important food crops for human and animal consumption, providing oil and protein at relatively low cost. The least expensive source of nitrogen for soybean is the biological fixation of atmospheric nitrogen by the symbiotic association with soil bacteria, belonging mainly to the genus Bradyrhizobium. This study was conducted to assess the effect of the inoculation of G. max with Bradyrhizobium japonicum on the metabolite profile and antioxidant potential of its seeds. Phenolic compounds, sterols, triterpenes, organic acids, fatty acids and volatiles profiles were characterised by different chromatographic techniques. The antioxidant activity was evaluated against DPPH, superoxide and nitric oxide radicals. Inoculation with B. japonicum induced changes in the profiles of primary and secondary metabolites of G. max seeds, without affecting their antioxidant capacity. The increase of organic and fatty acids and volatiles suggest a positive effect of the inoculation process. These findings indicate that the inoculation with nodulating B. japonicum is a beneficial agricultural practice, increasing the content of bioactive metabolites in G. max seeds owing to the establishment of symbiosis between plant and microorganism, with direct effects on seed quality. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Selection for later flowering in soybean (Glycine max L.Merrill F2 populations cultivated under short day conditions

    Directory of Open Access Journals (Sweden)

    Oliveira Antonio Carlos Baião de

    1999-01-01

    Full Text Available Several different selection strategies were used to estimate expected gain of days to flowering and other related characters in two F2 soybean (Glycine max (L. Merrill populations. The sample originated from crosses of lines whose seeds do not contain the three lipoxygenase isozymes with the commercially cultivated IAC-12. IAC-12 is a gene carrier for an extended juvenile period. This study was conducted during the winter of 1994 in Viçosa, Minas Gerais. The plants were grown under natural photoperiod. One population was grown in a heated greenhouse, and the other in the field under natural temperature conditions. Lower temperatures early in the field planting caused a delay in flowering. Delayed flowering caused a broader amplitude in all characters evaluated, and resulted in higher selection gains for the field-grown plants than for the greenhouse-grown plants. Direct selection for number of flowering days proved to be efficient for improving this character in both populations. Gains were also obtained for other characters. Interactions of temperature and photoperiod and temperature and genotypes affected soybean flowering time and produced alterations in other correlated agronomic characters, including productivity.

  7. When Your "Problem" Becomes Mine: Adult Female Siblings' Perspectives of Having a Brother with a Disability

    Science.gov (United States)

    Pompeo, Michelle N.

    2009-01-01

    This study is a retrospective look at adult female siblings' perspectives of their childhoods and present identities based on having a brother with a disability. This paper focuses on siblings' experiences within educational and public domains, and how such experiences have shaped their personalities and career choices. Qualitative findings were…

  8. A Thousand Lights [and] A Thousand Lights: Teacher and Parent Guide. Brothers Series.

    Science.gov (United States)

    Benton, Hope

    This book for children (ages 8 to 14) and the accompanying teacher/parent guide present the story of two brothers, one of whom has a severe hearing impairment, who climb up Mt. Fuji in Japan. Information on the disability is presented subtly and incidentally to encourage the reader to relate more personally and foster a deeper level of acceptance…

  9. Inherited germline ATRX mutation in two brothers with ATR-X syndrome and osteosarcoma.

    Science.gov (United States)

    Ji, Jianling; Quindipan, Catherine; Parham, David; Shen, Lishuang; Ruble, David; Bootwalla, Moiz; Maglinte, Dennis T; Gai, Xiaowu; Saitta, Sulagna C; Biegel, Jaclyn A; Mascarenhas, Leo

    2017-05-01

    We report a family in which two brothers had an undiagnosed genetic disorder comprised of dysmorphic features, microcephaly, severe intellectual disability (non-verbal), mild anemia, and cryptorchidism. Both developed osteosarcoma. Trio exome sequencing (using blood samples from the younger brother and both parents) was performed and a nonsense NM_000489.4:c.7156C>T (p.Arg2386*) mutation in the ATRX gene was identified in the proband (hemizygous) and in the mother's peripheral blood DNA (heterozygous). The mother is healthy, does not exhibit any clinical manifestations of ATR-X syndrome and there was no family history of cancer. The same hemizygous pathogenic variant was confirmed in the affected older brother's skin tissue by subsequent Sanger sequencing. Chromosomal microarray studies of both brothers' osteosarcomas revealed complex copy number alterations consistent with the clinical diagnosis of osteosarcoma. Recently, somatic mutations in the ATRX gene have been observed as recurrent alterations in both osteosarcoma and brain tumors. However, it is unclear if there is any association between osteosarcoma and germline ATRX mutations, specifically in patients with constitutional ATR-X syndrome. This is the first report of osteosarcoma diagnosed in two males with ATR-X syndrome, suggesting a potential increased risk for cancer in patients with this disorder. © 2017 Wiley Periodicals, Inc.

  10. 3 CFR 8466 - Proclamation 8466 of December 16, 2009. Wright Brothers Day, 2009

    Science.gov (United States)

    2010-01-01

    ... alter our world. Today, we honor the enduring American spirit of creativity and innovation that made the..., the Wright Brothers’ success embodies our Nation’s proud tradition of entrepreneurship. In pursuit of... failures, a skeptical public, and the sheer danger of their endeavors often tempted the brothers to quit...

  11. Brothers with constrictive pericarditis – A novel mutation in a rare disease

    Directory of Open Access Journals (Sweden)

    Devendra V. Patil

    2016-09-01

    Full Text Available Familial constrictive pericarditis is extremely rare. We report a case of two brothers both suffering constrictive pericarditis along with having multiple painless joint deformities. Genetic workup confirmed the clinical diagnosis of camptodactyly-arthropathy-coxa vara-pericarditis (CACP syndrome CACP syndrome and also revealed a rare mutation in the causative gene.

  12. "My Brother": The Recovery of Rocky in Leslie Marmon Silko's "Ceremony"

    Science.gov (United States)

    Bassett, Troy J.

    2004-01-01

    In Leslie Marmon Silko's novel "Ceremony", Rocky appears as Tayo's childhood friend and "brother" and also as a major part of Tayo's prisoner-of-war experiences in the Pacific during World War II. The interpretation of the novel presents both Rocky and Tayo as two men destroyed by the war, the former physically and the latter spiritually.

  13. Traits of ADHD and autism in girls with a twin brother

    DEFF Research Database (Denmark)

    Attermann, Jørn; Obel, Carsten; Bilenberg, Niels

    2012-01-01

    . In conclusion, we found that female twins with a twin brother scored significantly lower in parent-reported traits of ADHD and ASD than those with a twin sister. The reason for this may be parental reporting bias, or confounding by unmeasured variables, or a causal effect of an intrauterine environment modified...

  14. Brother-Sister Incest: Data from Anonymous Computer-Assisted Self Interviews

    Science.gov (United States)

    Stroebel, Sandra S.; O'Keefe, Stephen L.; Beard, Keith W.; Kuo, Shih-Ya; Swindell, Samuel; Stroupe, Walter

    2013-01-01

    Retrospective data were entered anonymously by 1,521 adult women using computer-assisted self interview. Forty were classified as victims of brother-sister incest, 19 were classified as victims of father-daughter incest, and 232 were classified as victims of sexual abuse by an adult other than their father before reaching 18 years of age. The…

  15. Two Brothers, Two Cities: Music Education in Boston and Cincinnati from 1830-1844

    Science.gov (United States)

    Lenzo, Terri Brown; Resta, Craig

    2011-01-01

    The birth of American music education is often attributed solely to Lowell Mason in Boston. His younger brother Timothy, however, was also active at the same time in Cincinnati. This study traces the roots of music education in both cities, but highlights the rarely cited accomplishments of Timothy Mason and his colleagues. Using historical…

  16. Desempenho de genótipos de soja-hortaliça de ciclo precoce [Glycine max (L. Merril] em diferentes densidades Performance of genotypes of early-cycle vegetable soybeans [Glycine max (L. Merril] in different densities

    Directory of Open Access Journals (Sweden)

    Hamilton César de O. Charlo

    2008-04-01

    Full Text Available Objetivando-se avaliar o desempenho de dois genótipos de soja-hortaliça de ciclo precoce [Glycine max (L. Merril], em diferentes densidades, foi instalado um ensaio, em área experimental do Setor de Olericultura e Plantas Aromático-Medicinais, pertencente ao Departamento de Produção Vegetal, nas dependências da Faculdade de Ciências Agrárias e Veterinárias (FCAV-UNESP, Campus de Jaboticabal-SP. O delineamento experimental foi o de parcelas subdivididas, adotando-se nas parcelas os genótipos e nas subparcelas as densidades, com quatro repetições por tratamento. Cada parcela experimental foi constituída por quatro linhas de 4,5m de plantio, com densidades de 20, 10 e 7 plantas por metro e 0,60m nas entrelinhas, sendo consideradas para avaliação 20 plantas por parcela, das duas linhas centrais. As sementes foram semeadas em bandejas de poliestireno expandido de 128 células, contendo substrato Plantmax Hortaliças®. O transplantio ocorreu dez dias após a semeadura, em solo devidamente preparado, conforme recomendações para a cultura. A colheita foi realizada quando os legumes estavam em estádio reprodutivo R6. Avaliaram-se os genótipos JLM010 e CNPSOI quanto às características: número médio de legumes por planta, número médio de sementes por legume, massa fresca de 100 sementes e produtividade estimada de grãos imaturos. Com base nos resultados obtidos concluiu-se que o genótipo JLM010 é o mais recomendado e deve ser plantado na densidade de 7 plantas por metro.With the aim of evaluating the performance of two genotypes of early-cycle soybeans [Glycine max (L. Merril] in different spacings, a study was carried out in the experimental area of the Sector of Vegetable Crops and Aromatic Medicinal Plants, belonging to the Department of Crop Sciences, College of Agricultural and Veterinary Sciences (FCAV-UNESP, Jaboticabal Campus-SP. The experimental design used was the one of subdivided parcels, each parcel representing

  17. Respon Kedelai (Gliycine Max L. Merril) terhadap Campuran Kompos Tandan Kosong Kelapa Sawit, Abu Boiler dan Trichoderma pada Gawangan Sawit Belum Menghasilkan di Lahan Gambut

    OpenAIRE

    Yunita, Rika; ', Nelvia

    2015-01-01

    This research aims to study the composition of the mixture of compost of oil palm empty fruit bunch (Compost of OPEFB), boiler ash and trichoderma on the growth aud yeilds of soybean (Glycine max L. Merrill) in oil palm plantations on peatlands. The experiment was conducted in the Kualu Nenas village, district of Kampar, Riau Province. Experiments used a randomized block design (RBD) consisting of 9 treatments, A (without treatment), B (1.56 kg compost of OPEFB)/plots, C (1.56 kg compost of O...

  18. Effect of gamma irradiation on microbial load, physicochemical and sensory characteristics of soybeans (Glycine max L. Merrill)

    International Nuclear Information System (INIS)

    Yun Juan; Li Xihong; Fan Xuetong; Tang Yao; Xiao Yao; Wan Sen

    2012-01-01

    Gamma irradiation is highly effective in inactivating microorganisms in various foods and offers a safe alternative method of food decontamination. In the present study, soybeans (Glycine max L. Merrill) were treated with 0, 1.0, 3.0, 5.0 and 10.0 KGy of gamma irradiation. Microbial populations on soybeans, isoflavone, tocopherol contents, raffinose family oligosaccharides, color and sensory properties were evaluated as a function of irradiation dose. The results indicated that gamma irradiation reduced aerobic bacterial and fungal load. Irradiation at the doses applied did not cause any significant change (p>0.05) in the contents of isoflavone of soybeans, but decreased tocopherol contents. The content of key flatulence-producing raffinose family oligosaccharides in irradiated soybeans (10.0 kGy) decreased by 82.1% compared to the control. Sensory analysis showed that the odor of the soybeans was organoleptically acceptable at doses up to 5.0 kGy and no significant differences were observed between irradiated and nonirradiated samples in flavor, texture and color after irradiation. - Highlights: ► The objective of this study concerns the elimination of microbial load factors at different radiation dose (0.0, 1.0, 3.0, 5.0 and 10.0 kGy). ► Investigated the degradation of the gamma irradiation on the reduction of flatulence-causing. ► Indicated the effect of irradiation on the isoflavone and tocopherol contents of the soybeans. ► Evaluated the effect of the gamma irradiation on the sensory properties of soybeans.

  19. Maailma börsid uues pöörises / Sirje Rank

    Index Scriptorium Estoniae

    Rank, Sirje, 1966-

    2008-01-01

    USA-st alanud finantskriis kogub uut hoogu. Investeerimispanga Lehman Brothers päästmine ebaõnnestus ning pank palus kohtult pankrotikaitset. Endine USA keskpanga juht Alan Greenspan ennustab veel mitme suur finantsasutuse pankrotti. Vt. samas: Lehman Brothers; Miks aktsiaturud langevad? Diagramm: USA finantskriisi järgmised ohvrid; Virge Lahe. USA finantskriis kergitab laenu hinda ka Eesti pankades

  20. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers.

    Science.gov (United States)

    Bandak, M; Jørgensen, N; Juul, A; Lauritsen, J; Kier, M G G; Mortensen, M S; Oturai, P S; Mortensen, J; Hojman, P; Helge, J W; Daugaard, G

    2017-07-01

    Testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to healthy controls. However, because of the fetal etiology of testicular cancer, familial unrelated healthy men might not be an optimal control group. The objective of this study was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39-50) vs. 46 (40-53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7-19). Serum levels of luteinizing hormone and follicle-stimulating hormone were elevated (p ≤ 0.001), while total testosterone, free testosterone, inhibin B and anti-Müllerian hormone were lower (p ≤ 0.001) in testicular cancer survivors than in their biological brothers. The prevalence of metabolic syndrome was similar and apart from HDL-cholesterol, which was lower in testicular cancer survivors (p = 0.01); there were no differences in the individual components of the metabolic syndrome between testicular cancer survivors and their brothers. In conclusion, gonadal function was impaired in testicular cancer survivors, while we did not detect any difference in the prevalence of metabolic syndrome between testicular cancer survivors and their biological brothers. © 2017 American

  1. Undersöka och förbättra Brother Finlands kommunikation, prissättning och leveransserviceelement

    OpenAIRE

    Forssell, Ronny; Nordström, Niklas

    2012-01-01

    Den nuvarande ekonomiska situationen har förorsakat en allt hårdare konkurrens på marknaderna vilket har lett till att företag hamnar kämpa för sina kundrelationer kraftigare. För Brother Finlands verksamhet spelar återförsäljarna en stor roll och därmed vill Brother Finland vara säker på att återförsäljarna är nöjda också i framtiden. Detta var orsaken till att Brother Finland blev intresserad av ett projekt i kundundersökningssyfte. Tre teman som Brother Finland såg som viktiga för en funge...

  2. Brothers and reduction of the birth weight of later-born siblings

    DEFF Research Database (Denmark)

    Nielsen, Henriette Svarre; Mortensen, Laust; Nygaard, Ulrikka

    2008-01-01

    It has been speculated whether maternal immune responses against male-specific minor histocompatibility (H-Y) antigens affect pregnancies negatively. This study explores, on a population level, whether previous births of boys compared with girls are associated with a decrease in birth weight...... of later-born siblings. The population was identified in the Danish Birth Registry and consisted of all Danish women who gave birth to their first-born singleton from 1980 to 1998. The women were followed until 2004, and their subsequent births were recorded. A total of 545,839 second- to fourth......-born children were identified. The authors used linear regression to analyze the association between sex of preceding children and birth weight of subsequent siblings. Brothers compared with sisters reduced the birth weight of later-born siblings. One or two brothers, respectively, reduced the mean birth weight...

  3. Discussing the Life of the Others: Doing Ethnography in the Brazilian Big Brother Fan Community

    Directory of Open Access Journals (Sweden)

    Bruno Campanella

    2009-05-01

    Full Text Available The aim of this paper is to present some of the initial results of ethnographic research conducted in early 2008 with the online fan community of the Brazilian Big Brother (BBB. After a brief introduction to some of the challenges faced by ethnographic work on television audiences in the last couple of decades, the current piece will explore some of the main characteristics constituting this new social space. Beyond the gossiping, and the more immediate talks about behaviors and game strategies of the Big Brother housemates, these forums sometimes trigger exchanges about Brazilian society at large, and the role of television broadcasting in general. Nonetheless, a closer inspection reveals how the debates found in the community are themselves permeated by the participants' struggle for status.

  4. Catholic nursing sisters and brothers and racial justice in mid-20th-century America.

    Science.gov (United States)

    Wall, Barbra Mann

    2009-01-01

    This historical article considers nursing's work for social justice in the 1960s civil rights movement through the lens of religious sisters and brothers who advocated for racial equality. The article examines Catholic nurses' work with African Americans in the mid-20th century that took place amid the prevailing social conditions of poverty and racial disempowerment, conditions that were linked to serious health consequences. Historical methodology is used within the framework of "bearing witness," a term often used in relation to the civil rights movement and one the sisters themselves employed. Two situations involving nurses in the mid-20th century are examined: the civil rights movement in Selma, Alabama, and the actions for racial justice in Chicago, Illinois. The thoughts and actions of Catholic sister and brother nurses in the mid-20th century are chronicled, including those few sister nurses who stepped outside their ordinary roles in an attempt to change an unjust system entirely.

  5. ATRX mutation in two adult brothers with non-specific moderate intellectual disability identified by exome sequencing

    OpenAIRE

    Moncini, S.; Bedeschi, M.F.; Castronovo, P.; Crippa, M.; Calvello, M.; Garghentino, R.R.; Scuvera, G.; Finelli, P.; Venturin, M.

    2013-01-01

    In this report, we describe two adult brothers affected by moderate non-specific intellectual disability (ID). They showed minor facial anomalies, not clearly ascribable to any specific syndromic patterns, microcephaly, brachydactyly and broad toes. Both brothers presented seizures. Karyotype, subtelomeric and FMR1 analysis were normal in both cases. We performed array-CGH analysis that revealed no copy-number variations potentially associated with ID. Subsequent exome sequence analysis allow...

  6. X-linked mental retardation syndrome: Three brothers with the Brooks-Wisniewski-Brown syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Morava, E.; Storcz, J.; Kosztolanyi, G. [Univ. Medical School, Pecs (Hungary)

    1996-07-12

    We report on 3 brothers with growth and mental retardation, bifrontal narrowness, short palpebral fissures, deeply set eyes with entropion, wide bulbous nose, small mouth, myopia, and spastic diplegia. The patients were born to normal and non-consanguineous parents. The similarity of our cases with those recently reported by Brooks et al. supports their suggestion that these patients are representative of a distinct entity. 8 refs., 3 figs., 1 tab.

  7. On Brothers and Sisters: South Asian and Japanese Idea Systems and their Consequences

    OpenAIRE

    Lyon, Stephen M.

    2017-01-01

    The role expectations of cross siblings varies across culture. Such expectations, while not rigidly prescribing actual behaviors nevertheless influences relations between brothers and sisters in observable ways. In South Asia, a cultural rhetoric of sororal sacrifice and support coupled with fraternal protection are commonplace. While such noble sibling roles are regularly transgressed they remain powerful idioms of the relationship and transgressions require appropriate cultural justificatio...

  8. A new syndrome: multiple congenital abnormalities and mental retardation in two brothers.

    Science.gov (United States)

    Dundar, M; Ozdemir, S Y; Fryns, J P

    2012-01-01

    In this report we present two brothers with abnormal neurological development, hypotonia, short stature, pylorus stenosis, pectus excavatum, brachycephaly due to craniosynostosis, frontal bossing, depressed nasal bridge, high arched-wide palate, downslant palpebral fissures, low-set, large ears, thin upper lip and bilateral cryptorchidism. The brothers were born to a couple of second cousins and were the third and fourth pregnancies of the mother. The father, the mother and the eldest sibling were phenotypically and chromosomally normal. The clinical findings of the brothers were found to be similar. These clinical findings were compared with syndromes showing some of the symptoms, namely Apert, FG, Floating-Harbor, Shprintzen-Goldberg and Rett Syndromes. However, when the findings were detailed, we observed that they did not match completely any of the syndromes in a discernable way. The MECP2 gene mutation was analysed because of mental retardation, poor neurological evolution and large ears, but no mutation was found. So these cases are presented as a new syndrome with apparent autosomal recessive inheritance.

  9. Cummings, Merrill, and Borrelli’s Inquiry into Small Screen Use by Academic Library Users: Timing is Everything

    Directory of Open Access Journals (Sweden)

    Catharine Bomhold

    2018-01-01

    Full Text Available A Review of: Cummings, J., Merrill, A., & Borrelli, S. (2010. The use of handheld mobile devices: Their impact and implications for library services. Library Hi Tech, (281, 22-40. https://doi.org/10.1108/07378831011026670 Abstract Objective – The authors undertook this study to understand the relatively new phenomenon of handheld computing and the use of small-screen devices among academic library users. They sought to determine if users would be inclined to search the online library catalogue on their devices and, by extension, if there would be a growing demand for small-screen compatible library services. Design – Online and paper surveys were used with both closed and open questions. Respondents included students, faculty, and staff at Washington State University (WSU. Setting – Washington State University Library, Pullman, Washington, United States of America. Subjects – The survey was open to any user of the Washington State University (Pullman Library. The 206 respondents included 126 (61.2% undergraduates, 26 (12.6% graduate or professional students, 32 (15.3% WSU employees, and 15 (7.3% faculty members. Methods – A survey was distributed both online and on paper. The online version used Surveymonkey.com and participation was solicited through various social media. It was open for three months during the Spring semester, 2007. The paper version was distributed to all library users on two days in June 2007. Eighty-four online and 122 paper responses were received. Main Results – Most of the respondents (58.4% who owned a personal digital assistant (PDA or Web-enabled cell phone (WECP indicated that they would search the library catalogue on a small-screen device. Responses to the open question “How would you use the OPAC [online public access catalogue] if it was available on a PDA or WECP?” were mixed, both positive and negative. The positive responders noted the possible time savings associated with the availability of

  10. Homozygous PARK7 Mutation in Parkinson’s Disease: Case Report of Two Brothers

    Directory of Open Access Journals (Sweden)

    Hülya Apaydın

    2008-06-01

    Full Text Available OBJECTIVE: Genetic studies for Parkinson’s disease (PD which have been increased during last few years have shown that parkin (PARK2, DJ-1 (PARK7 and PINK-1 (PARK6 mutations can cause autosomal recessive early-onset parkinsonism. OBJECTIVE: The aim of this study was to investigate by genetic screening methods, the presence of possible genetic mutations in two siblings who have developed PD. METHODS: In these two brothers, PD started at the age of 48 with cervical dystonia and bradykinesia on the left arm, and 56 with tremor on the right hand, respectively. Although they had a favorable response to levodopa, they developed wearing-off phenomenon without dyskinesia on the 4th year. Besides dystonia, the younger brother experienced psychosis and impulse control disorder, as well. Family history revealed first degree consanguinity and the father had also a diagnosis of PD. PD progressed rather slowly in both, but unfortunately the older brother died due to lung cancer 10 years after the initial diagnosis of PD, while he was on the stage 2 of Hoehn-Yahr scale. The younger brother is still on our follow-up at the 7th year of his PD. Informed consent was obtained and blood samples were sent to the genetic department of Juntendo University in Japan for genetic analysis. Parkin gene mutation and DJ-1 gene mutation were analyzed on the PARK7 locus, by automated direct nucleotide sequencing and performed gene dosage assay using TaqMan real-time quantitive PCR. RESULTS: After excluding the parkin mutation the presence of PARK7 was detected in both siblings with haplotype analysis. DJ-1 gene mutation analysis responsible for PARK7, revealed a deletion on intron 1. CONCLUSION: A rarely encountered PARK7 mutation was identified in two brothers having slowly progressive PD and a favorable response to levodopa, one of whom also had psychotic symptoms. As in the presented cases, the genetic studies performed on early-onset PD patients with positive family

  11. Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype.

    Science.gov (United States)

    Zhang, Yanliang; Liu, Yanhui; Li, Ya; Duan, Yong; Zhang, Keyun; Wang, Junwang; Dai, Yong

    2014-09-19

    We report on two brothers with a distinct syndromic phenotype and explore the potential pathogenic cause. Cytogenetic tests and exome sequencing were performed on the two brothers and their parents. Variants detected by exome sequencing were validated by Sanger sequencing. The main phenotype of the two brothers included congenital language disorder, growth retardation, intellectual disability, difficulty in standing and walking, and urinary and fecal incontinence. To the best of our knowledge, no similar phenotype has been reported previously. No abnormalities were detected by G-banding chromosome analysis or array comparative genomic hybridization. However, exome sequencing revealed novel mutations in the ATP-binding cassette, sub-family D member 1 (ABCD1) and Dachshund homolog 2 (DACH2) genes in both brothers. The ABCD1 mutation was a missense mutation c.1126G > C in exon 3 leading to a p.E376Q substitution. The DACH2 mutation was also a missense mutation c.1069A > T in exon 6, leading to a p.S357C substitution. The mother was an asymptomatic heterozygous carrier. Plasma levels of very-long-chain fatty acids were increased in both brothers, suggesting a diagnosis of adrenoleukodystrophy (ALD); however, their phenotype was not compatible with any reported forms of ALD. DACH2 plays an important role in the regulation of brain and limb development, suggesting that this mutation may be involved in the phenotype of the two brothers. The distinct phenotype demonstrated by these two brothers might represent a new form of ALD or a new syndrome. The combination of mutations in ABCD1 and DACH2 provides a plausible mechanism for this phenotype.

  12. Selection individual on mutant genotype of soybean (Glycine maxl.merrill) in m5 generation based on resistance of stem rot disease Athelia rolfsii (curzi)

    Science.gov (United States)

    Rahmah, M.; Hanafiah, D. S.; Siregar, L. A. M.; Safni, I.

    2018-02-01

    This study was aimed to obtain selected individuals on soybean plant Glycine max L. (Merrill) in M5 generation based on high production character and tolerance of stem rot disease Athelia rolfsii (Curzi). This research was conducted in Plant Disease Laboratory and experimental field Faculty of Agriculture Universitas Sumatera Utara Medan, Indonesia. This research was conducted from December 2016 to June 2017. The treatments were 15 mutant lines genotypes and Anjasmoro variety. The results showed that some lines mutant genotypes can gave the good agronomic appearance character than Anjasmoro variety on inoculation treatment of stem rot disease. Selection performed on population M5 producesselected individuals with tolerance of stem rot disease from 100 and 200 Gy population.

  13. Seleccion de cepas de rizobios en suelos promisorios para el cultivo de la soya (Glycine max (L Merril en Colombia

    Directory of Open Access Journals (Sweden)

    Sylvester Bradley Rosemary

    1989-06-01

    Full Text Available En el invernadero se evaluó la efectividad de las cepas preseleccionadas de B. japonicum (CIAT 199,209,3778,3874 y 3876 de la recomendada (CIAT51 y una de Rhizobium spp (CIAT 3779. En el suelo Fluventic Haplustoll, de reacción casi neutra, se presentó respuesta altamente significativa a la inoculación. El tratamiento fertilizado con 150 kg de N/ha produjo el mayor rendimiento de N. Las cepas más efectivas fueron CIAT 3778 y 51, que también presentaron el mayor indice de efectividad a la inoculación (IEI. En el suelo Typic Pellustert,de reacción alcalina, se presentó respuesta significativa a la inoculación. El mayor rendimiento de N se obtuvo con las cepas CIAT 3778 y 51, que fueron además estadísticamente iguales a las cepas CIAT 199 y 3876 en cuanto al IEI. En el suelo Arenic Haplustalf, de reacción ligeramente ácida, hubo respuesta altamente significativa a la inoculación y la cepa más efectiva fue la CJAT 199. En el suelo Fluventic Ustropept, de reacci6n ligeramente ácida, se presentaron diferencias significativas entre los tratamientos inoculados. El mayor rendimiento de N se presentó en el tratamiento fertilizado con N. Las mejores cepas fueron CIAT 3778,3779 y 209. En el suelo Vertic Ustropept, de reacción alcalina, se presentó respuesta altamente significativa a la inoculación. En cuanto al rendimiento de N no se encontraron diferencias entre el tratamiento fertilizado con N y las cepas CIAT 51, 209 y CIAT 3778, siendo también las más efectivas en cuanto al IEI, junto oon la cepa CIAT 199. En los suelos Tropentic Haplorthox y Typic Tropudult no se enoontró respuesta a la inoculación.Screening of Rhizobium strains in soils apt for soybean (Glycine max (L Merril cultivation in Colombia. Under greenhouse conditions were evaluated the effectivity of the preselected strains of the preselected strains of B. japonicum (CIAT 199, 209, 3778, 3874 and 3876, in addition to the recommended strain (CIAT 51 and one of

  14. Sicilian family with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) and lethal lung disease in one of the affected brothers.

    Science.gov (United States)

    De Luca, Filippo; Valenzise, Mariella; Alaggio, Rita; Arrigo, Teresa; Crisafulli, Giuseppe; Salzano, Giuseppina; Cervato, Sara; Mariniello, Barbara; Lazzarotto, Francesca; Betterle, Corrado

    2008-11-01

    We report the clinical and immunological features of the autoimmune regulator gene (AIRE) in two Sicilian brothers with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). They were compound heterozygotes with R203X/R257X. Both had oral candidiasis since the first year of life and later developed hypoparathyroidism and Addison disease. The elder brother had experienced recurrent lower respiratory infections since 5 years of age and over the years developed severe obstructive lung disease with bronchiectasis, which led to death at 18 years of age. Both brothers had circulating autoantibodies against tryptophan hydroxylase and serotonin-producing cells were absent in the duodenal mucosa. This was associated with intestinal dysfunction in only the elder brother. (1) In the first Sicilian family with APECED reported up to now we found a heterozygous mutation that had been previously reported only once. (2) In the older brother of this family we observed a severe and lethal lung disease; this case adds to a growing literature describing this association between APECED and respiratory illnesses. (3) Tryptophan hydroxylase antibodies might be hypothesized to be the marker of an autoimmune gastrointestinal illness possibly associated with APECED.

  15. Germline activating MTOR mutation arising through gonadal mosaicism in two brothers with megalencephaly and neurodevelopmental abnormalities.

    Science.gov (United States)

    Mroske, Cameron; Rasmussen, Kristen; Shinde, Deepali N; Huether, Robert; Powis, Zoe; Lu, Hsiao-Mei; Baxter, Ruth M; McPherson, Elizabeth; Tang, Sha

    2015-11-05

    In humans, Mammalian Target of Rapamycin (MTOR) encodes a 300 kDa serine/ threonine protein kinase that is ubiquitously expressed, particularly at high levels in brain. MTOR functions as an integrator of multiple cellular processes, and in so doing either directly or indirectly regulates the phosphorylation of at least 800 proteins. While somatic MTOR mutations have been recognized in tumors for many years, and more recently in hemimegalencephaly, germline MTOR mutations have rarely been described. We report the successful application of family-trio Diagnostic Exome Sequencing (DES) to identify the underlying molecular etiology in two brothers with multiple neurological and developmental lesions, and for whom previous testing was non-diagnostic. The affected brothers, who were 6 and 23 years of age at the time of DES, presented symptoms including but not limited to mild Autism Spectrum Disorder (ASD), megalencephaly, gross motor skill delay, cryptorchidism and bilateral iris coloboma. Importantly, we determined that each affected brother harbored the MTOR missense alteration p.E1799K (c.5395G>A). This exact variant has been previously identified in multiple independent human somatic cancer samples and has been shown to result in increased MTOR activation. Further, recent independent reports describe two unrelated families in whom p.E1799K co-segregated with megalencephaly and intellectual disability (ID); in both cases, p.E1799K was shown to have originated due to germline mosaicism. In the case of the family reported herein, the absence of p.E1799K in genomic DNA extracted from the blood of either parent suggests that this alteration most likely arose due to gonadal mosaicism. Further, the p.E1799K variant exerts its effect by a gain-of-function (GOF), autosomal dominant mechanism. Herein, we describe the use of DES to uncover an activating MTOR missense alteration of gonadal mosaic origin that is likely to be the causative mutation in two brothers who present

  16. The first mutation in CNGA2 in two brothers with anosmia

    DEFF Research Database (Denmark)

    Karstensen, H G; Mang, Y; Fark, T

    2015-01-01

    that the cyclic nucleotide-gated channel subunit CNGA2, expressed in the olfactory epithelium has a crucial role in olfactory signal transduction. We have identified a novel X-linked stop mutation in CNGA2 (c.634C>T, p.R212*) in two brothers with ICA using exome sequencing. No additional mutations in CNGA2 were...... identified in a cohort of 31 non-related ICA individuals. Magnetic resonance brain imaging revealed diminished olfactory bulbs and flattened olfactory sulci. This is the first report of a mutation in the cyclic nucleotide-gated gene CNGA2 and supports the critical role of this gene in human olfaction....

  17. [Two pairs of brothers with juvenile idiopathic arthritis (JIA): case reports].

    Science.gov (United States)

    Robazzi, Teresa Cristina M V; Rios, Gabriela; Castro, Catarina

    2015-01-01

    This is a case report of juvenile idiopathic arthritis (JIA) in two pairs of brothers followed in the department of pediatric rheumatology, Universidade Federal da Bahia. Genetic involvement in JIA pathogenesis is clear and the risk of recurrence among siblings supports this contribution. An important landmark of this discovery involves the acknowledgment of major histocompatibility complex (MHC) polymorphism contribution to JIA development susceptibility. Despite many advances, the numerous available studies cannot explain several implicit mechanisms in JIA pathogenesis yet. Copyright © 2012 Elsevier Editora Ltda. All rights reserved.

  18. “THE BROTHERS KARAMAZOV” IN GERMAN TRANSLATIONS: TRANSLATING THE RUSSIANNESS OF DOSTOYEVSKY’S STYLE

    Directory of Open Access Journals (Sweden)

    Olga KORENEVSKAYA

    2010-11-01

    Full Text Available : The article investigates the challenges of rendering the peculiarities of Dostoyevsky’s style linked to his philosophy of man and religious attitudes in four German translations of “The Brothers Karamazov”. The category of uncertainty is intrinsic to both Russian mentality and Dostoyevsky’s writing manner. However, the textual markers of uncertainty are perceived by German translators as essentially “foreign” and therefore may hinder the readers’ understanding. The paper reveals various approaches to conveying the desired semantic effect of uncertainty in the translations and points out problematic issues.

  19. Lipid myopathy associated with renal tubular acidosis and spastic diplegia in two brothers.

    Science.gov (United States)

    Tung, Y C; Tsau, Y K; Chu, L W; Young, C; Shen, Y Z

    2001-07-01

    Lipid myopathy is a group of disorders involving mitochondrial fatty acid oxidation. We describe two brothers, 3 years 8 months old and 2 years 9 months old, respectively, with progressive spastic diplegia, developmental delay, failure to thrive, and chronic metabolic acidosis who had lipid myopathy and renal tubular acidosis. Brain magnetic resonance imaging revealed demyelinating changes in the periventricular white matter, which was compatible with spastic diplegia. These symptoms may be related to errors in fatty acid metabolism. Cerebral palsy had been misdiagnosed in both of these patients at another hospital. Therefore, for patients with late-onset and progressive spastic diplegia, detailed investigations for underlying diseases are warranted.

  20. Living kidney transplantation between brothers with unrecognized renal amyloidosis as the first manifestation of familial Mediterranean fever: a case report.

    Science.gov (United States)

    Peces, Ramón; Afonso, Sara; Peces, Carlos; Nevado, Julián; Selgas, Rafael

    2017-08-31

    Familial Mediterranean fever is an autosomal recessive disease characterized by recurrent episodes of fever and polyserositis and by the onset of reactive amyloid-associated amyloidosis. Amyloidosis due to familial Mediterranean fever can lead to end-stage renal disease, culminating in kidney transplantation for some patients. In this study, we report the clinical outcome of two brothers with familial Mediterranean fever who were the inadvertent donor and recipient, respectively, of a kidney. Subsequently, they were diagnosed with renal amyloidosis secondary to familial Mediterranean fever and were successfully treated with anakinra and colchicine. Two brothers with familial Mediterranean fever and renal amyloidosis were the inadvertent donor and recipient, respectively, of a kidney. The recipient had presented recurrent acute febrile episodes of familial Mediterranean fever, developed nephrotic syndrome secondary to amyloidosis and needed bilateral nephrectomy and chronic dialysis. His elder brother, in apparent good health, donated his left kidney to his brother. Immediately after the kidney transplantation, both the donor and recipient presented massive proteinuria, impaired renal function and elevated serum amyloid A levels. Biopsies of the brothers' kidneys showed amyloidosis. Genetic studies thereafter revealed a homozygous variant for the MEFV gene (NM_000243.2.c.2082G > A; p.M694I) in both brothers. At this point, both the donor and recipient were treated with colchicine and anakinra, resulting in improved renal function, decreased proteinuria, undetectable serum amyloid A levels and stable renal function at 62 months of follow-up and no major adverse effects. In familial Mediterranean fever, analyses of the MEFV gene should be performed in potential live kidney donors from a direct family member (either between siblings or between parents and children). In addition, genetic studies are required when consanguinity is suspected between members involved in

  1. Bernoulli Brothers

    Indian Academy of Sciences (India)

    family flourished in business, but afterwards, its descendants. Utpal Mukhopadhyay is a teacher in Barasat. Satyabharati Vidyapith,. West Bengal. The Bernoulli .... problem, experts could readily recognise that the anonymous problem solver was none other than Sir Isaac Newton (1642-. 1727) and Johann commented on it ...

  2. A Monument as a Text, or The Message of the Brothers Dostoevsky

    Directory of Open Access Journals (Sweden)

    Vladimir Zakharov

    2014-12-01

    Full Text Available The article considers the circumstances of the creation of a monument to the writer's mother Maria Fyodorovna Dostoevskaya. Mikhail Andreevich, father of the brothers Dostoevsky, asked Mikhail and Fyodor to compose the text for the monument. In March and April of 1837 the brothers worked out the idea and conception of the monument, wrote the text of the first and fourth epigraphs, chose evangelic verses and an epitaph of N.M. Karamzin. This was their first collective act of creative work embodied in stone. The monument is not only a symbol of love and sorrow for their mother’s death but also hope for her salvation and future resurrection. The brothers’ words and those chosen from the Gospel as well as the Karamzin’s ones have one more meaning. These convey a sense of beingness and an Easter idea of individual creative work. It is necessary to renew the tomb of Maria Fyodorovna Dostoevskaya and bring the monument back to Lazarevskoye cemetery in Moscow.

  3. Birth order and ratio of brothers to sisters in Spanish transsexuals.

    Science.gov (United States)

    Gómez-Gil, Esther; Esteva, Isabel; Carrasco, Rocío; Almaraz, M Cruz; Pasaro, Eduardo; Salamero, Manel; Guillamon, Antonio

    2011-06-01

    Three Western studies have shown that male-to-female (MF) homosexual transsexuals tend to be born later than their siblings and to come from sibships with more brothers than sisters. The objective of this study was to determine whether these variables would be replicated in 530 MF and female-to-male (FM) Spanish transsexuals according to sexual orientation. The results showed that MF homosexual transsexuals had significantly more older brothers than the non-homosexual MF group. Compared with the expected rates in the general population, birth order was significantly higher in both MF (Slater's Index = 0.59; Fraternal Index = 0.61; Sororal Index = 0.58) and FM homosexual transsexuals (Slater's Index = 0.65; Fraternal Index = 0.68; Sororal Index = 0.67), and sibling sex ratio was significantly higher than expected in homosexual MF (sex ratio = 0.55) but not in homosexual FM transsexuals. No significant differences were found in the non-homosexual subgroups. The replication of the later birth order and sibling sex-ratio effect in MF homosexual transsexuals corroborates previous findings in a variety of groups from different cultures and may suggest a common mechanism underlying the etiology of transsexualism.

  4. Exubera. Inhale therapeutic systems.

    Science.gov (United States)

    Bindra, Sanjit; Cefalu, William T

    2002-05-01

    Inhale, in colaboration with Pfizer and Aventis Pharma (formerly Hoechst Marion Roussel; HMR), is developing an insulin formulation utilizing its pulmonary delivery technology for macromolecules for the potential treatment of type I and II diabetes. By July 2001, the phase III program had been completed and the companies had begun to assemble data for MAA and NDA filings; however, it was already clear at this time that additional data might be required for filing. By December 2001, it had been decided that the NDA should include an increased level of controlled, long-term pulmonary safety data in diabetic patients and a major study was planned to be completed in 2002, with the NDA filed thereafter (during 2002). US-05997848 was issued to Inhale Therapeutic Systems in December 1999, and corresponds to WO-09524183, filed in February 1995. Equivalent applications have appeared to date in Australia, Brazil, Canada, China, Czech Republic, Europe, Finland, Hungary, Japan, Norway, New Zealand, Poland and South Africa. This family of applications is specific to pulmonary delivery of insulin. In February 1999, Lehman Brothers gave this inhaled insulin a 60% probability of reaching market, with a possible launch date of 2001. The analysts estimated peak sales at $3 billion in 2011. In May 2000, Aventis predicted that estimated peak sales would be in excess of $1 billion. In February 2000, Merrill Lynch expected product launch in 2002 and predicted that it would be a multibillion-dollar product. Analysts Merril Lynch predicted, in September and November 2000, that the product would be launched by 2002, with sales in that year of e75 million, rising to euro 500 million in 2004. In April 2001, Merrill Lynch predicted that filing for this drug would occur in 2001. Following the report of the potential delay in regulatory filing, issued in July 2001, Deutsche Banc Alex Brown predicted a filing would take place in the fourth quarter of 2002 and launch would take place in the first

  5. ATRX mutation in two adult brothers with non-specific moderate intellectual disability identified by exome sequencing.

    Science.gov (United States)

    Moncini, S; Bedeschi, M F; Castronovo, P; Crippa, M; Calvello, M; Garghentino, R R; Scuvera, G; Finelli, P; Venturin, M

    2013-12-01

    In this report, we describe two adult brothers affected by moderate non-specific intellectual disability (ID). They showed minor facial anomalies, not clearly ascribable to any specific syndromic patterns, microcephaly, brachydactyly and broad toes. Both brothers presented seizures. Karyotype, subtelomeric and FMR1 analysis were normal in both cases. We performed array-CGH analysis that revealed no copy-number variations potentially associated with ID. Subsequent exome sequence analysis allowed the identification of the ATRX c.109C>T (p.R37X) mutation in both the affected brothers. Sanger sequencing confirmed the presence of the mutation in the brothers and showed that the mother is a healthy carrier. Mutations in the ATRX gene cause the X-linked alpha thalassemia/mental retardation (ATR-X) syndrome (MIM #301040), a severe clinical condition usually associated with profound ID, facial dysmorphism and alpha thalassemia. However, the syndrome is clinically heterogeneous and some mutations, including the c.109C>T, are associated with a broad phenotypic spectrum, with patients displaying a less severe phenotype with only mild-moderate ID. In the case presented here, exome sequencing provided an effective strategy to achieve the molecular diagnosis of ATR-X syndrome, which otherwise would have been difficult to consider due to the mild non-specific phenotype and the absence of a family history with typical severe cases.

  6. Incestuous sisters: mate preference for brothers over unrelated males in Drosophila melanogaster.

    Directory of Open Access Journals (Sweden)

    Adeline Loyau

    Full Text Available The literature is full of examples of inbreeding avoidance, while recent mathematical models predict that inbreeding tolerance or even inbreeding preference should be expected under several realistic conditions like e.g. polygyny. We investigated male and female mate preferences with respect to relatedness in the fruit fly D. melanogaster. Experiments offered the choice between a first order relative (full-sibling or parent and an unrelated individual with the same age and mating history. We found that females significantly preferred mating with their brothers, thus supporting inbreeding preference. Moreover, females did not avoid mating with their fathers, and males did not avoid mating with their sisters, thus supporting inbreeding tolerance. Our experiments therefore add empirical evidence for inbreeding preference, which strengthens the prediction that inbreeding tolerance and preference can evolve under specific circumstances through the positive effects on inclusive fitness.

  7. Brothers with hypospadias, vertebral segmentation defects, and intellectual disability: new syndrome?

    Science.gov (United States)

    Phadke, Shubha R; Ranganath, Prajnya; Boggula, Vijay Raju; Gupta, Divya; Phadke, Rajendra V; Sloman, Melissa; Turnpenny, Peter D

    2012-12-01

    We report on two brothers (born to nonconsanguineous parents) with short stature, hypospadias, scoliosis, vertebral segmentation defects of "spondylocostal dysostosis" type, and intellectual disability. Results of cytogenetic and molecular genetic tests performed, including routine karyotype, MLPA (multiplex ligation-dependent probe amplification) for common microdeletions and subtelomeric copy number variants, microarray-CGH analysis, and sequencing of four Notch signaling pathway genes (DLL3, MESP2, LFNG, and HES7), were all normal. We present a comparison of the condition in the two boys with known syndromes and suggest that they may represent a hitherto unreported syndrome, most likely following autosomal recessive inheritance, though X-linked inheritance is not excluded. Copyright © 2012 Wiley Periodicals, Inc.

  8. [1896: How nascent radiotherapy gathered Roentgen, Pasteur and the Lumière brothers].

    Science.gov (United States)

    Foray, N

    2016-12-01

    On the 4th July, 1896, in his medical office of Les Échelles (Savoie, France), Victor Despeignes performed the very first radiotherapy against cancer, documented by indisputable proofs. However, the intellectual and practical approach that leads to this first radiotherapy may appear unexpected to date. Indeed, it is likely that the treatment that Despeignes applied to his neighbour, who did not suffer from stomach cancer, was born with the indirect support of the Lumière brothers, on the basis of a biological theory (the parasitory theory of cancer) that is irrelevant today, with an experimental protocol based on experiments performed on tuberculosis et in a bifractionated model linked by the constraints of a district medical doctor. Copyright © 2016 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

  9. Hiper-realidade versus sedução: o paradoxo do Big Brother Brasil

    Directory of Open Access Journals (Sweden)

    Felipe da Silva Polydoro

    2011-07-01

    Full Text Available ResumoNeste artigo, jogamos Baudrillard contra si próprio na análise do programa Big Brother Brasil (BBB. Primeiro, desenvolvemos a afirmação do teórico de que este reality show resume-se a refletir o estado de banalidade de uma cultura hiper-real. Em seguida, propomos uma reversão nesta argumentação, ao apontar, no BBB, sinais de um efeito sedutor. No início, recuperarmos alguns pontos da teoria do autor francês e evidenciamos o conceito moderno de realidade, aquilo que desaparece na era da simulação.

  10. Sustained virologic response following HCV eradication in two brothers with X-linked agammaglobulinaemia.

    LENUS (Irish Health Repository)

    Houlihan, Diarmaid D

    2009-08-21

    X-linked agammaglobulinaemia (XLA) is a humoral immunodeficiency syndrome characterized from childhood by the absence of circulating B lymphocytes, absent or reduced levels of serum immunoglobulin and recurrent bacterial infections. For many affected patients, regular treatment with immunoglobulin is life saving. Hepatitis C viral (HCV) infection acquired through contaminated blood products is widely described in this patient cohort. The natural history of HCV infection in patients with XLA tends to follow a more rapid and aggressive course compared to immunocompetent individuals. Furthermore, standard anti-viral therapy appears to be less efficacious in this patient cohort. Here we report the cases of two brothers with XLA who contracted HCV through contaminated blood products. They were treated with a six month course of Interferon alpha-2b and Ribavirin. We report a sustained virologic response five years after completing treatment.

  11. Cobb′s collar occurring in two brothers in a family: A rare entity revisited

    Directory of Open Access Journals (Sweden)

    Partha Pal

    2014-01-01

    Full Text Available Most urethral strictures arise from iatrogenic, traumatic, or inflammatory causes. We report the familial occurrence of a congenital bulbar urethral stricture in two brothers. Retrograde and voiding cystourethrography was performed. A Cobb′s collar was diagnosed after radiological and endoscopic evaluation in both cases and was successfully managed with urethroplasty. Cobb′s collar is a rarely recognized cause of a membranous stricture of bulbar urethra that can lead to several urinary problems. In cases of adolescent and young adults presenting with symptoms of progressive urinary obstruction and enuresis with or without urinary tract infection, Cobb′s collar can be seen as a minor constriction in the bulbar urethra, but is not frequently symptomatic, and the familial occurrence of such a stricture is even rarer.

  12. A sterile sperm caste protects brother fertile sperm from female-mediated death in Drosophila pseudoobscura

    DEFF Research Database (Denmark)

    Holman, Luke; Snook, Rhonda R

    2008-01-01

    Spermicide (i.e., female-mediated sperm death) is an understudied but potentially widespread phenomenon that has important ramifications for the study of sexual conflict, postcopulatory sexual selection, and fertility [1, 2]. Males are predicted to evolve adaptations against spermicide, but few...... antispermicidal mechanisms have been definitively identified. One such adaptation may be the enigmatic infertile sperm morphs or "parasperm" produced by many species, which have been hypothesized to protect their fertile brother "eusperm" from spermicide [2, 3]. Here, we show that female Drosophila pseudoobscura...... reproductive tracts are spermicidal and that the survival of eusperm after exposure to the female tract is highest when males produce many parasperm. This study clarifies the adaptive significance of infertile sperm castes, which has remained elusive in Drosophila and other taxa despite much recent interest [2...

  13. [The brothers of Jumiege--the peripheral nervous system in early French mythology].

    Science.gov (United States)

    Brean, Are

    2002-03-20

    This article reviews the process of discovery of the nervous system from Pythagoras (570-500 BC) to Galen (130-201 AD). After Galen, no anatomical studies were performed before the renaissance. According to a legend, probably produced for political reasons, two brothers, sons of the French king Clovis II, revolted against their father and were sentenced to loose their physical powers by having the nerves of their arms and legs cut. They were then set adrift on the river Seine, stranding at the Jumiège monastery. The earliest written version of this legend stems from the fourteenth century; it was probably a part of the local French mythology. This indicates that the existence of the peripheral nervous system, and therefore also in part the knowledge contained in the early anatomical works, quite early may have been more or less known outside academic circles.

  14. CONFESSION AND REPENTANCE IN F. M. DOSTOYEVSKY'S NOVEL THE BROTHERS KARAMAZOV

    Directory of Open Access Journals (Sweden)

    Denis Vladimirovich Vasil'ev

    2014-11-01

    Full Text Available The article deals with the meaning of a penitential confession in Fyodor Dostoyevsky's novel The Brothers Karamazov. It is noted that the penitential confession in the novel exempts from the burden of guilt, allowing the confessor to get rid of spiritual suff erings through the compassion of the person who accepts the confession and shares the guilt with the sinner. It is emphasized that repentance is inseparably linked with overcoming the sense of shame before public exposure and self-obsession with one’s reputation. The attention is paid to mutual confessions in the novel aft er which the heroes step on the path towards transformation. It is concluded that penitential confessions of heroes result in their revival and spiritual renewal, as each of them is given a chance to endure spiritual revolution, to overcome the "hell" and to confirm the validity of Zosima’s idea about common guilt and responsibility.

  15. Old Instruments, New Agendas: The Chemical Brothers and the ARP 2600

    Directory of Open Access Journals (Sweden)

    Hans T. Zeiner-Henriksen

    2014-06-01

    Full Text Available A preference for old vintage music equipment is widespread in electronic dance music. My point of departure for a discussion of this phenomenon is an interview from Keyboard magazine in which the members of the production duo the Chemical Brothers proclaim their fascination with an old analogue synthesizer. Two diverse theoretical approaches will inform and nuance my narrative here. Wiebe E. Bijker’s sociotechnical approach to the development of technology will highlight stages and processes in the transition from analogue to digital technology. In addition, Sarah Thornton’s concept of subcultural capital will direct attention to the old instrument as a prestige item that serves to maintain power structures within the electronic dance music culture.

  16. From Glass Architecture to Big Brother: Scenes from a Cultural History of Transparency

    Directory of Open Access Journals (Sweden)

    Scott McQuire

    2013-09-01

    Full Text Available In this essay, I want to reposition the Big Brother phenomenon in the context of an earlier debate about domestic space which occurred during the emergence of architectural modernism in the first decades of the twentieth century. At issue then was the physical reconstruction of the home, particularly through the increasing use of glass as a design element. While glass architecture is even more prevalent in the present, its spatial impact—particularly in terms of its capacity to alter the relationship between the ‘inside’ and the ‘outside’—has now been matched or exceeded in many respects by the effects of electronic media. By tracing the parallel between the unsettling spatial effects produced by both glass construction and the electronic screen, I will sketch a cultural logic linking the modernist project of architectural transparency to the contemporary repositioning of the home as an interactive media centre.

  17. Observations of Local Seismicity and Harmonic Tremor Using an Ocean Bottom Hydrophone Array at Brothers Volcano, South Kermadec Arc.

    Science.gov (United States)

    Haxel, J. H.; Dziak, R. P.; Lau, T. K.; Matsumoto, H.

    2005-12-01

    The submarine Brothers volcano is an important link in the volcanic chain of the southern Kermadec Arc system in the Southwest Pacific Ocean north of New Zealand. The 3-3.5 km wide caldera has a center depth of 1850m and steep surrounding walls of 300-450m. Active hydrothermal venting distinguished Brothers as a point of focus for the New Zealand American Submarine Ring of Fire (NZASRoF) expeditions in 2004 and 2005. Due to its remote location, moderate to small magnitude seismicity around the Brothers area is largely unknown. In late September 2004, four ocean bottom hydrophones (OBHs) were deployed on the caldera floor. In April 2005, three of the four instruments were recovered intact. These three OBHs continuously recorded, for seven months, the low frequency (0-110Hz) acoustic field around Brothers volcano, in particular seismic P- and S-waves propagating through the crust and acoustic T-waves in the water column . Preliminary analysis reveals seismicity rates on the order of 106 earthquakes per month. In addition to seismic arrivals, low frequency harmonic tremor is frequently and independently observed on each of the OBH instruments, often occurring subsequent to the larger seismic events. Qualitative comparisons of these signals with tremor observed from the Volcano Islands south of Japan (Dziak and Fox, 2002) show them to be nearly equivalent in frequency structure, suggesting the origin of the tremor observed at Brothers may also be attributed to resonance of a magma-gas mixture in a large chamber or conduit near the water/ seafloor boundary.

  18. Extreme intrafamilial variability of Saudi brothers with primary hyperoxaluria type 1

    Directory of Open Access Journals (Sweden)

    Alfadhel M

    2012-08-01

    Full Text Available Majid Alfadhel,1 Khalid A Alhasan,2 Mohammed Alotaibi,3 Khalid Al Fakeeh41Division of Genetics, Department of Pediatrics, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia; 2Division of Nephrology Department of Pediatrics, King Saud University King Khalid University Hospital, Riyadh, Saudi Arabia; 3Department of Radiology, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia; 4Division of Nephrology, Department of Pediatrics, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi ArabiaBackground: Primary hyperoxaluria type 1 (PH1 is characterized by progressive renal insufficiency culminating in end-stage renal disease, and a wide range of clinical features related to systemic oxalosis in different organs. It is caused by autosomal recessive deficiency of alanine:glyoxylate aminotransferase due to a defect in AGXT gene.Case report: Two brothers (one 6 months old; the other 2 years old presented with acute renal failure and urinary tract infection respectively. PH1 was confirmed by high urinary oxalate level, demonstration of oxalate crystals in bone biopsy, and pathogenic homozygous known AGXT gene mutation. Despite the same genetic background, same sex, and shared environment, the outcome of the two siblings differs widely. While one of them died earlier with end-stage renal disease and multiorgan failure caused by systemic oxalosis, the older brother is pyridoxine responsive with normal development and renal function.Conclusion: Clinicians should be aware of extreme intrafamilial variability of PH1 and international registries are needed to characterize the genotype-phenotype correlation in such disorder.Keywords: primary hyperoxaluria, oxalosis, PH1, intrafamilial variability

  19. Emisiones de óxido nitroso en un cultivo de soja [Glycine max (L. Merrill]: efecto de la inoculación y de la fertilización nitrógenada Nitrous oxide emission during a soybean [Glycine max (L. Merril] culture: inoculation and nitrogen fertilization effects

    Directory of Open Access Journals (Sweden)

    Ignacio A Ciampitti

    2005-12-01

    Full Text Available El óxido nitroso absorbe radiación infrarroja contribuyendo al efecto invernadero; este gas es producido principalmente en el suelo, mediante los procesos de nitrificación y denitrificación. En un estudio a campo, sobre un suelo Argiudol típico, se evaluó el efecto de la fertilización y la inoculación con Bradyrhizobium japonicum en un cultivo de soja [Glycine max (L. Merrill], sobre las emisiones de óxido nitroso. Los gases se extrajeron de cilindros de PVC y la lectura se realizó con cromatografía gaseosa. Las emisiones presentaron valores crecientes desde la siembra hacia madurez fisiológica del cultivo, para todos los tratamientos; este comportamiento fue concomitante con la evolución presentada por la humedad edáfica. La fertilización nitrogenada aumentó significativamente (PNitrous oxide gas absorbs infrared radiation contributing to the greenhouse effect; this gas is produced mainly in soil, by means of the processes of nitrification and denitrification. In a field study at the FAUBA on a typic Argiudol, we evaluated the effect of fertilization and inoculation with Bradyrhizobium japonicum during a soybean culture [Glycine max (L. Merrill], on nitrous oxide emisión. Gases were sampled with PVC cylinders and were read with gaseous chromatography. Emissions presented increasing values from seeding towards physiological maturity for all treatments; this behavior was similar to the evolution presented by nitrate level and soil moisture. Nitrogen fertilization significantly increased (P<0.05 nitrous oxide emissions and inoculation only had a significant effect with the highest level of fertilization (P=0.09. Plots fertilized at highest dose and inoculated gave the greatest nitrous oxide emissions. The variable that better explains the emissions is the nitrate level (r² = 0.1899; P=0.0231.

  20. Yield response of soy bean cultivars (Glycine max [L.] Merrill to the application of different doses of biofertilizer FitoMás–E

    Directory of Open Access Journals (Sweden)

    Yanitza Meriño Hernández

    2015-02-01

    Full Text Available This research was done under field conditions, from December 2012 through February 2013. The objective was to evaluate the yield response of soy bean (Glycine max [L.] Merrill, variety “INCASOY-24”, to the application of different doses of FitoMás-E, in a randomized block experimental design with 4 treatments: T1 (control, T2 (1 L.ha-1, T3 (1.5 L.ha-1 and T4 (2 L.ha-1, and 4 replications. The bioestimulant was applied to foliage early in the morning from the 10th day after germination. The data were analyzed statistically with Statistica, ver. 8.0 software. When the indicators used showed significant differences, the Duncan’s Multiple Range Test was applied to p < 0.05. The results of each evaluated variable showed a significant effect of FitoMás-E on the cultivar. The best results were achieved where the application dose was 1 L.ha-1 (T2.

  1. Submarine hydrothermal activity and gold-rich mineralization at Brothers Volcano, Kermadec Arc, New Zealand

    Science.gov (United States)

    de Ronde, Cornel E. J.; Massoth, Gary J.; Butterfield, David A.; Christenson, Bruce W.; Ishibashi, Junichiro; Ditchburn, Robert G.; Hannington, Mark D.; Brathwaite, Robert L.; Lupton, John E.; Kamenetsky, Vadim S.; Graham, Ian J.; Zellmer, Georg F.; Dziak, Robert P.; Embley, Robert W.; Dekov, Vesselin M.; Munnik, Frank; Lahr, Janine; Evans, Leigh J.; Takai, Ken

    2011-07-01

    Brothers volcano, of the Kermadec intraoceanic arc, is host to a hydrothermal system unique among seafloor hydrothermal systems known anywhere in the world. It has two distinct vent fields, known as the NW Caldera and Cone sites, whose geology, permeability, vent fluid compositions, mineralogy, and ore-forming conditions are in stark contrast to each other. The NW Caldera site strikes for ˜600 m in a SW-NE direction with chimneys occurring over a ˜145-m depth interval, between ˜1,690 and 1,545 m. At least 100 dead and active sulfide chimney spires occur in this field and are typically 2-3 m in height, with some reaching 6-7 m. Their ages (at time of sampling) fall broadly into three groups: metal-rich, and gas-poor. Calculated end-member fluids from NW Caldera vents indicate that phase separation has occurred, with Cl values ranging from 93% to 137% of seawater values. By contrast, vent fluids at the Cone site are diffuse, noticeably cooler (≤122°C), more acidic (pH 1.9), metal-poor, and gas-rich. Higher-than-seawater values of SO4 and Mg in the Cone vent fluids show that these ions are being added to the hydrothermal fluid and are not being depleted via normal water/rock interactions. Iron oxide crusts 3 years in age cover the main cone summit and appear to have formed from Fe-rich brines. Evidence for magmatic contributions to the hydrothermal system at Brothers includes: high concentrations of dissolved CO2 (e.g., 206 mM/kg at the Cone site); high CO2/3He; negative δD and δ18OH2O for vent fluids; negative δ34S for sulfides (to -4.6‰), sulfur (to -10.2‰), and δ15N2 (to -3.5‰); vent fluid pH values to 1.9; and mineral assemblages common to high-sulfidation systems. Changing physicochemical conditions at the Brothers hydrothermal system, and especially the Cone site, occur over periods of months to hundreds of years, as shown by interlayered Cu + Au- and Zn-rich zones in chimneys, variable fluid and isotopic compositions, similar shifts in 3He/4He

  2. The two Haydns and the brothers hospitallers (Barmherzige Brüder, Fatebene frateli, Osi):The four pupils, the less known sources

    Czech Academy of Sciences Publication Activity Database

    Freemanová, Michaela

    2001-01-01

    Roč. 38, 3-4 (2001), s. 333-342 ISSN 0018-7003 Institutional research plan: CEZ:AV0Z8059909 Keywords : brothers hospitallers, J and M. Haydn, pupils Subject RIV: AL - Art, Architecture, Cultural Heritage

  3. Phelan-McDermid syndrome in two adult brothers: atypical bipolar disorder as its psychopathological phenotype?

    Directory of Open Access Journals (Sweden)

    Verhoeven WMA

    2012-04-01

    Full Text Available Willem MA Verhoeven1,2, Jos IM Egger1,3,4, Marjolein H Willemsen5, Gert JM de Leijer6, Tjitske Kleefstra51Vincent van Gogh Institute for Psychiatry, Centre of Excellence for Neuropsychiatry, Venray, 2Erasmus University Medical Centre, Department of Psychiatry, Rotterdam, 3Donders Centre for Cognition, Radboud University Nijmegen, Nijmegen, 4Behavioural Science Institute, Radboud University Nijmegen, Nijmegen, 5Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, 6Dichterbij, Institutes for Intellectual Disabilities, Gennep, The NetherlandsAbstract: The 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep disturbances, communication deficits, and motor perseverations. Data on psychological dysfunctions are so far not available. Previous studies have suggested that the loss of one copy of the gene SH3 and multiple ankyrin repeat domains 3 (SHANK3 is related to the neurobehavioral phenotype. Additional genes proximal to SHANK3 are also likely to play a role in the phenotype of patients with larger deletions. The present paper describes two adult brothers with an identical 2.15 Mb 22qter (22q13.32q13.33 deletion, of whom the youngest was referred for evaluation of recurrent mood changes. In both patients, magnetic resonance imaging of the brain showed hypoplasia of the vermis cerebelli. Extensive clinical examinations led to a final diagnosis of atypical bipolar disorder, of which symptoms fully remitted during treatment with a mood stabilizer. In the older brother, a similar psychopathological picture appeared to be present, although less severe and with a later onset. It is concluded that the behavioral phenotype of the 22q13.3 deletion syndrome comprises absent or delayed speech and perseverations

  4. Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype

    Directory of Open Access Journals (Sweden)

    Nadia Skauli

    2016-11-01

    Full Text Available Biallelic PIGT variants were previously reported in seven patients from three families with Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 (MCAHS3, characterized by epileptic encephalopathy, hypotonia, global developmental delay/intellectual disability, cerebral and cerebellar atrophy, craniofacial dysmorphisms, and skeletal, ophthalmological, cardiac, and genitourinary abnormalities. We report a novel homozygous PIGT missense variant c.1079G>T (p.Gly360Val in two brothers with several of the typical features of MCAHS3, but in addition, pyramidal tract neurological signs. Notably, they are the first patients with MCAHS3 without skeletal, cardiac, or genitourinary anomalies. PIGT encodes a crucial subunit of the glycosylphosphatidylinositol (GPI transamidase complex, which catalyzes the attachment of proteins to GPI-anchors, attaching the proteins to the cell membrane. In vitro studies in cells from the two brothers showed reduced levels of GPI-anchors and GPI-anchored proteins on the cell surface, supporting the pathogenicity of the novel PIGT variant.

  5. Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype

    OpenAIRE

    Skauli, Nadia; Wallace, Sean; Chiang, Samuel C. C.; Bar?y, Tuva; Holmgren, Asbj?rn; Stray-Pedersen, Asbj?rg; Bryceson, Yenan T.; Str?mme, Petter; Frengen, Eirik; Misceo, Doriana

    2016-01-01

    Biallelic PIGT variants were previously reported in seven patients from three families with Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 (MCAHS3), characterized by epileptic encephalopathy, hypotonia, global developmental delay/intellectual disability, cerebral and cerebellar atrophy, craniofacial dysmorphisms, and skeletal, ophthalmological, cardiac, and genitourinary abnormalities. We report a novel homozygous PIGT missense variant c.1079G>T (p.Gly360Val) in two brothers w...

  6. Megacystis-microcolon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had prune belly syndrome: common pathogenesis?

    Science.gov (United States)

    Oliveira, G; Boechat, M I; Ferreira, M A

    1983-01-01

    A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with prune belly syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.

  7. Megacystis-microlon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had Prune Belly syndrome: Common Pathogenesis

    International Nuclear Information System (INIS)

    Oliveira, G.; Boechat, M.I.; Fereira, M.A.

    1983-01-01

    A case of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with Prune Belly Syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process. (orig.)

  8. Megacystis-microlon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had Prune Belly syndrome: Common Pathogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, G.; Boechat, M.I.; Fereira, M.A.

    1983-07-01

    A case of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with Prune Belly Syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.

  9. Reluctant Romantics – On the fairy tale poetics of the Brothers Grimm and their relationship to German Romanticism

    Directory of Open Access Journals (Sweden)

    Isabel dos Santos

    2014-12-01

    Full Text Available The legacy of the Brothers Grimm continues to fascinate readers and researchers alike. The 200-year anniversary of the first publication of their fairy tales sparked a renewed interest in the life, work and times of the brothers. Fascinated by the past, by the political present and by the literary future of Romanticism, the Brothers Grimm stayed together in an unusual working union. They established what was to become German philology and published many invaluable works on language and history, myths and folk tales. This article will focus on the brothers’ place in German Romanticism through their contribution of fairy tales. The period was marked by political and philosophical thought that emphasised authentic experienced and the spiritual unity of art, science and philosophy. There was a strong call for national emancipation. Literature was required to embody this unity through an established national literature founded on German folk traditions. The Grimms seemed to have heeded that call. But a careful study reveals that their intentions were motivated less by the literary movement than by their own strong convictions which they upheld even at the cost of compromising the authenticity they claimed to uphold in their poetics. The many controversies regarding the origins, collection and editing of the fairy tales is inextricably linked to the brothers’ difficult relationship with the Romantic Movement. Two hundred years later, this article seeks to give an appraisal of the Brothers’ motivation for their poetics and of the research conducted thus far.

  10. Barcode System for Genetic Identification of Soybean [Glycine max(L.) Merrill] Cultivars Using InDel Markers Specific to Dense Variation Blocks.

    Science.gov (United States)

    Sohn, Hwang-Bae; Kim, Su-Jeong; Hwang, Tae-Young; Park, Hyang-Mi; Lee, Yu-Young; Markkandan, Kesavan; Lee, Dongwoo; Lee, Sunghoon; Hong, Su-Young; Song, Yun-Ho; Koo, Bon-Cheol; Kim, Yul-Ho

    2017-01-01

    For genetic identification of soybean [ Glycine max (L.) Merrill] cultivars, insertions/deletions (InDel) markers have been preferred currently because they are easy to use, co-dominant and relatively abundant. Despite their biological importance, the investigation of InDels with proven quality and reproducibility has been limited. In this study, we described soybean barcode system approach based on InDel makers, each of which is specific to a dense variation block (dVB) with non-random recombination due to many variations. Firstly, 2,274 VBs were mined by analyzing whole genome data in six soybean cultivars (Backun, Sinpaldal 2, Shingi, Daepoong, Hwangkeum, and Williams 82) for transferability to dVB-specific InDel markers. Secondly, 73,327 putative InDels in the dVB regions were identified for the development of soybean barcode system. Among them, 202 dVB-specific InDels from all soybean cultivars were selected by gel electrophoresis, which were converted as 2D barcode types according to comparing amplicon polymorphisms in the five cultivars to the reference cultivar. Finally, the polymorphism of the markers were assessed in 147 soybean cultivars, and the soybean barcode system that allows a clear distinction among soybean cultivars is also detailed. In addition, the changing of the dVBs in a chromosomal level can be quickly identified due to investigation of the reshuffling pattern of the soybean cultivars with 27 maker sets. Especially, a backcross-inbred offspring, "Singang" and a recurrent parent, "Sowon" were identified by using the 27 InDel markers. These results indicate that the soybean barcode system enables not only the minimal use of molecular markers but also comparing the data from different sources due to no need of exploiting allele binning in new varieties.

  11. The effect of soil tillage system and weeding time on the growth of weed and yield of soybean (Glycine max (L. Merril

    Directory of Open Access Journals (Sweden)

    Husni Thamrin Sebayang

    2018-04-01

    Full Text Available The growth and yield of soybeans can decrease due to competition from weeds. Various efforts have been made to control the growth of weeds such as land preparation and weeding periods. An experiment to study the effect of soil tillage systems and weeding time on the growth of weeds and soybean crop yield (Glycine max (L. Merril has been done in Wringinsongo Village, Tumpang Sub-District, Malang Regency from February to May 2017. The split-plot design with three replicates was used with the soil tillage system as the main plot consisting of three levels, T0: no tillage, T1: minimum tillage, and T2: conventional tillage, and weeding time as the sub plot consisting of 4 levels, P0: no weeding, P1: weeding 1 time, P2: weeding two times and P3: weeding three times. The results showed that the dominant weed species before treatment were Amaranthus spinosus (Spiny amaranth, Cynodon dactylon (Bermuda grass, Cyperus rotundus (Purple nutsedge, Ageratum conyzoides (Billygoat weed, and Portulaca oleracea (Common purslane. After treatment, the dominant weed species were Cyperus rotundus (Purple nutsedge, Amaranthus spinosus (Spiny amaranth, Ageratum conyzoides (Billygoat weed, Physalis peruviana (Cape gooseberry, and Eclipta alba (False daisy. There was no significant difference of the dry weight of weeds in conventional tillage followed by weeding 3 times at 15, 30 and 45 days after planting, and minimum tillage and no tillage. For the yield of soybeans, conventional tillage followed by weeding 3 times at 15, 30 and 45 days after planting were not significant with that of minimum tillage. The yield of soybeans was lower than that of with no tillage and no weeding.

  12. Challenging stereotypes? The older woman in the TV series Brothers & Sisters.

    Science.gov (United States)

    Oró-Piqueras, Maricel

    2014-12-01

    The TV series, Brothers & Sisters, broadcast from 2006 to 2011 by ABC (USA) and a year later by Channel 4 (UK) with quite high audience rates, starts when the patriarchal figure, William Walker, dies of a heart attack and two female figures around their sixties come center stage: his wife, Nora Walker, and his long-term lover, Holly Harper. Once the patriarchal figure disappears, the female characters regain visibility by entering the labor market and starting relationships with other men. In that sense, both protagonists experience aging as a time in which they are increasingly freed from social and family constraints. However, their roles as nurturers keep on bringing them back to the domestic space in which they are safe from being involved in uncomfortable and unsuitable situations. Drawing on previous studies on the representation of the older woman in fictional media, this article intends to discern to what extent stereotypes related to the older woman are challenged through the two main protagonists of a contemporary TV series. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. [Cancer of the oral cavity in three brothers of the whole blood in Mauritania].

    Science.gov (United States)

    Baba, Nacer Dine

    2016-01-01

    Major risk factors for cancers of the oral cavity are alcohol and tobacco, but hereditary factors were also identified. This case study aims to illustrate this last component among the most known risk factors. We here report three cases of brothers of the whole blood presenting with cancer of the oral cavity showing rapid development in less than a year in each of them. Additional risk factors other than hereditary factors were: smoking, poor oral hygiene, low fruit and vegetable intake. Hereditary risk has been a controversial issue for a long period of time, but several recent studies have suggested the existence of this risk factor which is consistent with our observation. These studies even showed that hereditary component for carcinomas of the upper aerodigestive tract seems likely; it is important that family members at risk understand that their vulnerability to these tumors can be greatly reduced by stopping smoking, by a moderate consumption of alcohol and a frequent consumption of raw fruits and vegetables. Further studies should be carried out in our country to clarify the respective role of these different risk factors in developing this type of cancer Meanwhile, prevention and early diagnosis are the most appropriate means to fight against this type of cancer.

  14. [Fragile X syndrome and white matter abnormalities: Case study of two brothers].

    Science.gov (United States)

    Wallach, E; Bieth, E; Sevely, A; Cances, C

    2017-03-01

    Fragile X syndrome is the most usual cause of hereditary intellectual deficiency. Typical symptoms combine intellectual deficiency, social anxiety, intense emotional vigilance, and a characteristic facial dysmorphy. This is subsequent to a complete mutation of the FMR1 gene, considering a semidominant transmission linked to the unstable X. The expansion of the CGG triplet greater than 200 units combined with a high methylation pattern lead to a transcriptional silence of the FMR1 gene, and the protein product, the FMRP, is not synthesized. This protein is involved in synaptic plasticity. Brain MRI can show an increased volume of the caudate nucleus and hippocampus, combined with hypoplasia of the cerebellar vermis. Fragile X Associated Tremor Ataxia Syndrome (FXTAS) syndrome is a neurodegenerative disorder occurring in carriers of the premutation in FMR1. Brain MRI shows an increased T2 signal in the middle cerebellar peduncles. This syndrome is linked to a premutation in the FMR1 gene. We report here the case of two brothers presenting a typical fragile X symptomatology. Brain MRI showed hyperintensities of the middle cerebellar peduncles. Such MRI findings support the assumption of a genetic mosaicism. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  15. Super Mario brothers and sisters: Associations between coplaying video games and sibling conflict and affection.

    Science.gov (United States)

    Coyne, Sarah M; Jensen, Alexander C; Smith, Nathan J; Erickson, Daniel H

    2016-02-01

    Video games can be played in many different contexts. This study examined associations between coplaying video games between siblings and levels of affection and conflict in the relationship. Participants were 508 adolescents (M age = 16.31 years of age, SD = 1.08) who completed questionnaires on video game use and sibling relationships. Participants were recruited from a large Northwestern city and a moderate city in the Mountain West of the United States. Video games played between siblings were coded by an independent sample to assess levels of physical aggression and prosocial behavior in each game. Playing video games with a sibling was associated with higher levels of sibling affection for both boys and girls, but higher levels of conflict for boys only. Playing a violent video game with a brother was associated with lower levels of conflict in the sibling relationship, whereas playing a prosocial video game was not related to any sibling outcome. The value of video games in sibling relationships will be discussed, with a focus on the type of game and the sex of the adolescent. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  16. 'The brothers Karamazov' and 'On the open road': F. M. Dostoevsky and Steve Tesich's moral imperative

    Directory of Open Access Journals (Sweden)

    Šoškić Radoje V.

    2012-01-01

    Full Text Available The present paper strives to analyze the play On the Open Road, the most famous and most popular play by American-Serbian playwright and screenwriter Steve Tesich, comparing some of its elements and ideas to F. M. Dostoevsky's novel The Brothers Karamazov, whose episodic interpolation yet its moral centre - the legend of the Grand Inquisitor, inspired Tesich to use the motif of Christ's Second Coming in his play. In this play, Tesich deliberately resorts to allegory in order to critically perceive and react to the growing deterioration of the moral sensibility of Western civilization embroiled in hypocrisy and lies. The murder of Christ, from Tesich's perspective, is a dramatic example of the process of killing what is best in man, a process that is constantly repeated in the dehumanized social order that is imposed by force, and persists due to the use of force. Tesich, as well as his contemporary Arthur Miller, dramatizes the killing of God in man as the killing and drying up of man's creative potentialities and conscience. .

  17. Sixty Days Remaining, Forty Years of CERN, Two Brothers, One Exclusive Interview

    CERN Multimedia

    2001-01-01

    Twins Marcel and Daniel Genolin while sharing memories of their CERN experiences, point out just how much smaller the Meyrin site once was. In a place such as CERN where the physical sciences are in many ways the essence of our daily lives and where technological advancement is an everyday occurrence, it is easy to lose track of the days, months, and even years. But last week twin brothers, Daniel and Marcel Genolin, hired in the early sixties and getting ready to end their eventful forty year CERN experiences, made it clear that the winds of time bluster past us whether we are aware or not. 'CERN was very small when we started' says Marcel, who has worked in transport during his entire time here. A lot has changed. 'When I got here there were no phones in peoples' houses' he recalls,'when there were problems in the control room with the PS (Proton Synchrotron) they used to get a megaphone and tell us {the transport service} to go and get the necessary physicists from their homes in the area. We had to lo...

  18. Langenud Gorilla / Kertu Ruus

    Index Scriptorium Estoniae

    Ruus, Kertu, 1977-

    2008-01-01

    Ilmunud ka: Delovõje Vedomosti 24. sept. lk. 8-9. USA investeerimispanga Lehman Brothers tegevjuhist Dick Fuldist. Vt. samas: Richard S. Fuld: CV; Ameerika unistuste täitja: vendade investeerimispank; Taust; Kommenteerivad: Madis Toomsalu ja Jonathan Well

  19. Analýza vývoje derivátových trhů v průběhu finanční krize

    OpenAIRE

    Zikmund, Michal

    2011-01-01

    The aim of my final thesis is the derivatives markets development analysis during financial crisis. Through basic problems with derivatives accounts of Lehman Brothers we can assess needs of standardization and transparency in area of derivatives instruments with such result which has minimal impact for liquidity on derivatives market. In the next step, there was analyzed year 2008 alone because of bankruptcy announcement of Lehman Brothers and therefore was analyzed impact on derivatives pro...

  20. Legal consequences for torture in children cases: the Gomez Paquiyauri Brothers vs Peru case.

    Science.gov (United States)

    Tinta, Monica Feria

    2009-01-01

    The Gomez Paquiyauri Brothers case, before the Inter-American Court of Human Rights, was the first international case concerning the protection of children in the context of armed conflict where an international court stated the law concerning the duties of States towards children even in the context of war, and provided for reparations. As such it represents a landmark decision. The case arose from the illegal detention, torture and extrajudicial execution of two minors, Emilio and Rafael Gomez Paquiyauri, at the hands of Peruvian Police in 1991, under the Fujimori Administration at a time when the internal war in Peru was at its peak. Unlike most cases coming to the jurisdiction of the Inter-American Court, the case had been subject to domestic criminal investigations that had led to the convictions of two low ranking policemen. Yet a more subtle pattern of impunity lied at the root of the case. Torture had been denied by the State, and the prosecutions of low ranking policemen had intended to cover up the responsibility of those who ordered a policy of torture and executions (including the existence of secret codes for the torture and elimination of suspects of "terrorism") during the years of the internal armed conflict in Peru. The joint work of legal and medical expertise in the litigation of the case permitted the establishment of the facts and the law, obtaining an award of 740,500 dollars for the victims and a number of measures of reparation including guarantees of non-repetition and satisfaction, such as the naming of a school after the victims.

  1. A Song in the Dark. Francis of Assisi’s Canticle of Brother Sun

    Directory of Open Access Journals (Sweden)

    Speelman Willem Marie

    2016-10-01

    Full Text Available The Canticle of the Creatures or Canticle of Brother Sun is based on a particular way of perceiving reality. Francis, who had turned away from ‘the world’, discovered a different way of looking at it. This is a divine way of perceiving, in which the senses do not grasp reality, but accept it as it communicates itself. This way of perceiving is only possible if one does not attempt to master the environment, but allows one’s senses to be weak. It is significant, therefore, that this song of praise was born at a moment of the utmost despair and weakness. The song’s content is in line with this weak perception: it is not about Francis who praises God and (or for His creatures, but rather it is a testimony that the creatures-the elements-are already praising God, and a prayer that He should let Himself be praised by the creatures. Also in line with this weak perception is the fact that the creatures are praised just as they communicate themselves to Francis: as bodies. The theology of this song is that the creatures through their bodies resonate (strengthen, and colour the blessings that come from God, thereby making His blessing present here on earth. Francis’ role is to give a voice and a language to the heavenly praises as they resound in his environment. The transformative power of this song is that we, whether consciously or not, do the same thing when we participate in this song.

  2. Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages.

    Science.gov (United States)

    Bidon, Tobias; Janke, Axel; Fain, Steven R; Eiken, Hans Geir; Hagen, Snorre B; Saarma, Urmas; Hallström, Björn M; Lecomte, Nicolas; Hailer, Frank

    2014-06-01

    Brown and polar bears have become prominent examples in phylogeography, but previous phylogeographic studies relied largely on maternally inherited mitochondrial DNA (mtDNA) or were geographically restricted. The male-specific Y chromosome, a natural counterpart to mtDNA, has remained underexplored. Although this paternally inherited chromosome is indispensable for comprehensive analyses of phylogeographic patterns, technical difficulties and low variability have hampered its application in most mammals. We developed 13 novel Y-chromosomal sequence and microsatellite markers from the polar bear genome and screened these in a broad geographic sample of 130 brown and polar bears. We also analyzed a 390-kb-long Y-chromosomal scaffold using sequencing data from published male ursine genomes. Y chromosome evidence support the emerging understanding that brown and polar bears started to diverge no later than the Middle Pleistocene. Contrary to mtDNA patterns, we found 1) brown and polar bears to be reciprocally monophyletic sister (or rather brother) lineages, without signals of introgression, 2) male-biased gene flow across continents and on phylogeographic time scales, and 3) male dispersal that links the Alaskan ABC islands population to mainland brown bears. Due to female philopatry, mtDNA provides a highly structured estimate of population differentiation, while male-biased gene flow is a homogenizing force for nuclear genetic variation. Our findings highlight the importance of analyzing both maternally and paternally inherited loci for a comprehensive view of phylogeographic history, and that mtDNA-based phylogeographic studies of many mammals should be reevaluated. Recent advances in sequencing technology render the analysis of Y-chromosomal variation feasible, even in nonmodel organisms. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e

  3. Power in Play: A Foucauldian Reading of A.O. Soyinka’s The Trials of Brother Jero

    Directory of Open Access Journals (Sweden)

    Mahboobeh Davoodifar

    2015-12-01

    Full Text Available This work utilizes Foucault’s articulations on the power strategies of our contemporary society. To him the subject’s constitution is never a purely passive effect of power on the subject but requires the subject’s own activity. This necessitates the existence of a dynamic, mutually affecting relationship, implying that one can be both dominated and dominate at different times and in different contexts. This article aims to analyze the Nigerian Noble Laureate, Wole Soyinka’s play The Trials of Brother Jero, a prophetical play that criticizes the ills of society through its satirical depiction, in the light of Foucault’s conceptualizations on power. To do this, the article first clarifies Foucault’s mature understanding of the operation of power and then attempts to provide an in-depth analysis of the structure of the power regime and its relations in the play, tactics of domination, and more importantly, the characters’ relations to the existing system of power. The study of the language and the dialogue of the main characters, Brother Jero, Amope, Chume and a Member of Federation House not only exposes the sources of operating power relations, but it also highlights the characters’ desire for power and the way it flows and slips from one character to another. The findings of the paper reveals that power is not concentrated on merely one character or institution within the play, rather, it circulates, and through the active resistance of the dominated characters, it constantly engenders new meanings within the structure of the play. In The Trials of Brother Jero, different characters have the desire to use power against each other and the resistance of each of them indicates that power is neither possessive nor repressive. Keywords: Michel Foucault, Power, Pastoral Power, Resistance, Wole Soyinka

  4. A Clarion Call for Social Work Attention: Brothers and Sisters of Persons With Acquired Brain Injury in the United States.

    Science.gov (United States)

    Degeneffe, Charles Edmund

    2016-08-11

    This article presents a clarion call for increased social work attention to the needs of siblings of persons with acquired brain injury (ABI) in the United States. The article overviews how siblings are psychosocially affected, how they provide care to the injured brothers and sisters, and how they personally develop as a result of their experiences. The article highlights the fact that social workers and other professionals often overlook the needs of siblings of persons with ABI and makes an appeal for social workers to advance clinical practice and research to benefit this often neglected population.

  5. Race and the refusal to name racism: consumption, identity and choice in the Celebrity Big Brother House

    OpenAIRE

    Thomas, Dania

    2009-01-01

    The centrality of consumption in the resolution of the ‘race row’ in the Celebrity Big Brother(CBB) House 2007 characterizes ‘the consumption politics of race’ engendered in response to ‘racism lite’ (adopting Mary Riddell’s term) - forms of racial harm articulated in normative frames specific to the entertainment industry. The regulatory response to racism litewas premised on a radical and post-modern framing of race and racial harm. When compared with the responses to racism outside the CBB...

  6. Structures, stability, mechanical and electronic properties of a-boron and its twined brother a*-boron

    OpenAIRE

    He, Chaoyu; Zhong, Jianxin

    2013-01-01

    The structures, stability, mechanical and electronic properties of a-boron and its twined brother a*-boron have been studied by first-principles calculations. Both a-boron and a*-boron consist of equivalent icosahedra B12 clusters in different connecting configurations of "3S-6D-3S" and "2S-6D-4S", respectively. The total energy calculations show that a*-boron is less stable than a-boron but more favorable than beta-boron and Gamma-boron at zero pressure. Both a-boron and a*-boron are confirm...

  7. Adubação foliar com macro e micronutrientes no crescimento de mudas micropropagadas do abacaxizeiro cv. Gold [Ananas comosus (L. Merrill] em diferentes recipientes Foliar fertilization with macro and micronutrients in the growth of plantlets micropropagated of pineapple cv. Gold [Ananas comosus (L. Merrill] in different containers

    Directory of Open Access Journals (Sweden)

    Izaias dos Santos Bregonci

    2008-06-01

    Full Text Available Objetivou-se com este trabalho avaliar o efeito da adubação foliar com macro e micronutrientes no crescimento das mudas micropropagadas do abacaxizeiro cv. Gold [Ananas comosus (L. Merrill], em diferentes recipientes. O experimento foi em esquema fatorial 8x3, adubação foliar em 8 níveis e recipientes em 3 níveis, através de um delineamento inteiramente casualizado com 5 repetições. As mudas foram padronizadas com altura média de 7,12 cm. As adubações foliares foram feitas com uréia, cloreto de potássio, ácido bórico, um formulado comercial com macro e micronutrientes e testemunha (pulverização com água e os recipientes: bandeja de isopor com 200 células; tubete pequeno de 115 cm³; e tubete grande com 300 cm³. O substrato utilizado foi o plantmax hortaliças®. Avaliaram-se as características área foliar, altura de planta e massa seca da parte aérea e da raiz, aos 140 dias do transplantio. Os adubos foliares proporcionaram maior crescimento em área foliar, altura e massa seca da parte aérea às mudas do abacaxizeiro, embora com resultados diferentes. Os adubos foliares não aumentaram a massa seca do sistema radicular. A bandeja de isopor apresentou as menores médias, com todos os adubos foliares para área foliar, altura e massa seca da parte aérea das mudas do abacaxizeiro. O tubete pequeno e o tubete grande apresentaram resultados semelhantes com a maioria dos adubos foliares utilizados.The objective of this work was to evaluate the effect of the foliar fertilization with macro and micronutrients on the growth of the plantlets micropropagated of pineapple cv. Gold [Ananas comosus (L. Merrill] in different containers. The experiment was mounted in factorial arrangement 8x3, with foliar fertilization in 8 levels and containers in 3 levels, through a completely randomized design with five repetitions. The plantlets were standardized with average height of 7,12 cm. The foliar fertilization was used in the urea

  8. Polinização por Apis mellifera em soja transgênica [Glycine max (L. Merrill] Roundup Ready™ cv. BRS 245 RR e convencional cv. BRS 133 = Pollination by Apis mellifera in transgenic soy (Glycine max (L. Merrill Roundup Ready™ cv. BRS 245 RR and conventional cv. BRS 133

    Directory of Open Access Journals (Sweden)

    Tais da Silva Lopes

    2008-04-01

    Full Text Available O objetivo deste estudo foi verificar a influência de Apis mellifera na produção de grãos e qualidade de sementes da soja transgênica Glycine max (L. Merrill Roundup Ready™ e convencional. A soja transgênica foi plantada intercalada com a convencional, em 18 parcelas, em três tratamentos: gaiolas com abelhas A. mellifera, gaiolas sem abelhas e áreas descobertas, com livre visitação de insetos. Na soja transgênica, em três parcelas de cada tratamento, foi aplicado glifosato, 30 dias após a emergência. Os parâmetros analisados foram: produção de grãos; número de vagens por planta; peso de 100 sementes e porcentagem de germinação das sementes. Não houve diferença entre as cultivares, entretanto a produção de 2.757,40 kg ha-1 obtida na área coberta por gaiola com abelhas, e2.828,47 kg ha-1 na área livre para visitação de insetos foram superiores a 2.000,53 kg ha-1 da área coberta por gaiola sem abelhas. O número de vagens por planta foi maior na área coberta por gaiola com abelhas (38,28 e área livre (32,65, quando comparado com o daárea coberta por gaiola sem abelhas (21,19. O peso médio de 100 sementes e a germinação das sementes não foram diferentes entre as cultivares e nem entre os tratamentos. Concluise que, para as cultivares estudadas, houve benefício na produção de grãos de 37,84%,quando foi permitida a visita de abelhas.This research was carried out to evaluate the influence of Africanized honeybees in grain production and seed quality of Glycine max (L. Merrill Roundup Ready™ transgenic soy, as well as of conventional soy. Transgenic soy was interposed with conventional soybean, in 18 plots and three treatments: covered area with Africanized honeybees, covered area without honeybees, and uncovered area with free insect visitation. The herbicide Glyphosate was applied on three plots of each treatment of transgenic soy, 30 days after emergence. Grain production, number of pods/plant, weight per

  9. Culture-independent characterization of a novel microbial community at a hydrothermal vent at Brothers volcano, Kermadec arc, New Zealand

    Science.gov (United States)

    Stott, M. B.; Saito, J. A.; Crowe, M. A.; Dunfield, P. F.; Hou, S.; Nakasone, E.; Daughney, C. J.; Smirnova, A. V.; Mountain, B. W.; Takai, K.; Alam, M.

    2008-08-01

    The bacterial and archaeal diversity of a hydrothermal vent microbial community at Brothers volcano situated in the Kermadec arc, ˜400 km off the north coast of New Zealand, was examined using culture-independent molecular analysis. An unusual microbial community was detected with only 1% and 40% of the bacterial phylotypes exhibiting >92% small subunit (SSU) rRNA gene sequence similarity with cultivated and noncultivated microbes, respectively. Of the 29 bacterial representative phylotypes, over one third of the SSU rRNA gene sequences retrieved belonged to uncultivated candidate divisions including OP1, OP3, OP5, OP8, OD1, and OP11. All archaeal phylotypes belonged to the phylum Euryarchaeota in the uncultivated groups deep hydrothermal vent euryarchaeotal (DHVE) I and II or to the phylum Korarchaeota. Like the bacterial clone library, only a small proportion of archaeal SSU rRNA gene sequences (˜2% and 20%) displayed >92% sequence identity with any archaeal isolates or noncultivated microbes, respectively. Although the bacterial phylotypes detected were phylogenetically most similar to microbial communities detected in methane, hydrocarbon, and carbon dioxide-based hydrothermal and seep environments, no phylotypes directly associated with anaerobic methane oxidation and mcrA activity could be detected. The geochemical composition of the vent fluids at the Brothers-lower cone sample site is unusual and we suggest that it may play a prominent role in the species selection of this microbial community.

  10. Different types of glomerulonephritis associated with the dysregulation of the complement alternative pathway in 2 brothers: A case report.

    Science.gov (United States)

    Chen, Pei; Zhu, Li; Yu, Feng; Han, Sha-Sha; Meng, Si-Jun; Guo, Wei-Yi; Zhang, Hong; Song, Yan

    2017-06-01

    C3 glomerulonephritis (C3GN) and complement-mediated hemolytic uremic syndrome (HUS) both result from the abnormal regulation of the complement system. A significant number of patients with C3GN or complement-mediated HUS have mutations of more than 1 complement protein. This discovery has had a major impact on identifying the underlying cause of familial C3GN or complement-mediated HUS. We report the cases of 2 brothers (herein referred to as patient II-1 and patient II-9), both with complement disorders that differed in their clinical and genetic features. Patient II-1 clinically presented with nephrotic syndrome and acute kidney injury and pathologically presented with C3GN combined with thrombotic microangiopathy (TMA) and subacute tubulointerstitial nephritis. Meanwhile, patient II-9 clinically presented with HUS and pathologically presented with TMA combined with acute severe tubular injury. Screenings for genetic mutations contributed to complement system dysregulation were performed on patient II-1. The genome sequencing identified that patient II-1 had a heterozygous mutation in the C3 gene (c.C1774T/p.R592W). Nine other relatives of the brothers were checked for this C3 mutation and only the daughter of patient II-1 (herein referred to as patient III-2) carried it, but so far, she does not have any clinical manifestations of kidney disease. Family members with a dysregulation of the complement alternative pathway may differ in its clinical and genetic features.

  11. Discordant Clinical Course of Vitamin-D-Hydroxylase (CYP24A1 Associated Hypercalcemia in Two Adult Brothers With Nephrocalcinosis

    Directory of Open Access Journals (Sweden)

    Tilman Jobst-Schwan

    2015-08-01

    Full Text Available Background/Aims: Hypercalcemia can result in nephrocalcinosis/nephrolithiasis and may lead to renal failure. Idiopathic infantile hypercalcemia is caused by mutations of the CYP24A1 gene, which regulates vitamin D activity. Classically infants present with hypercalcemia. Recently, a number of individuals have been reported with late onset clinical manifestation or late diagnosis in adulthood. All these patients are believed to show hypercalciuria. Methods: We report a 24 year old patient of healthy consanguine parents. Genetic analysis was performed by Sanger sequencing of the CYP24A1 gene in the index patient and targeted exon 2 analysis of all other family members. Results: The patient was hospitalized with severe malaise during an acute EBV-infection. He showed hypercalcemia > 3mmol/l and acute, hypovolemic renal failure with profound nephrocalcinosis, but no hypercalciuria. Genetic workup revealed a homozygous loss-of-function mutation p.E143del in the CYP24A1 gene. His clinically asymptomatic brother showed nephrocalcinosis of lesser degree. Repeatedly, low parathyroid hormone levels were detected in both brothers. Conclusion: This family displays the highly variable phenotype of CYP24A1 biallelic mutation carriers. CYP24A1 associated disease is an important differential diagnosis for the workup and counseling of infants as well as adults with hypercalcemia since a proper genetic diagnosis may result in therapeutic consequences.

  12. Palmo-Plantar hyperkeratosis, intellectual disability, and spastic paraplegia in two maternal half brothers: further evidence for an X-linked inheritance.

    Science.gov (United States)

    Isidor, Bertrand; Lefebvre, Tiphaine; Barbarot, Sébastien; Perrier, Julie; Mercier, Sandra; Péréon, Yann; Le Caignec, Cédric; David, Albert

    2013-06-01

    In 1983, Fitzsimmons et al. reported four brothers with an unrecognized disorder characterized by intellectual disability, spastic paraplegia, and palmo-plantar hyperkeratosis (OMIM 309500). In this report, we describe a family in which two males, maternal half-brothers, had learning disabilities. Both patients also showed spasticity in the lower limbs and palmo-plantar hyperkeratosis. The mother of the affected boys had learning difficulties but did not show any dermatological symptoms. This report confirms that the association of features reported by Fitzsimmons et al. is a distinct entity and further suggests an X-linked mode of inheritance. Copyright © 2013 Wiley Periodicals, Inc.

  13. EFECTO DEL CONTENIDO DE HUMEDAD Y NIVEL DE COMPACTACIÓN DE UN SUELO ULTISOL SOBRE ALGUNAS CARACTERÍSTICAS BROMATOLÓGICAS DEL CULTIVO DE SOYA (Glycine max L. Merril cv San Baiba | EFFECT OF MOISTURE CONTENT AND LEVEL OF COMPACTION OF AN ULTISOL SOIL ON SOME BROMATOLOGIC characteristics OF CULTIVATION OF SOYBEAN (Glycine max L. Merrill cv San Baiba

    Directory of Open Access Journals (Sweden)

    María Trujillo Galindo

    2016-10-01

    Full Text Available Debido a que los problemas de compactación de suelos como limitante en el desarrollo de los cultivos han sido tradicionalmente estudiados de manera independiente del factor humedad, se realizó un experimento para determinar el comportamiento del cultivo de Soya (Glycine max L. Merrill cv San Baiba con respecto a la humedad y la compactación de un suelo Ultisol de la sabana del estado Monagas, Venezuela. Se utilizó un diseño de bloques al azar en arreglo factorial donde se estudió la interacción de cuatro niveles de compactación a través de diferentes número de golpes por capa (0, 12, 24, 36 y cuatro de humedad a través de la variación de la frecuencias de riego (todos los días, cada dos días, cada tres días y cada cuatro días. Se evidenció que la masa fresca foliar y de ramas, así como el área foliar se vieron afectadas por la frecuencia de riego arrojando las siguientes ecuaciones de regresión, respectivamente: Y = 905,035 + 1691,364 x - 390,280 x2 con un R2 = 98,12 %, Y = 16,770 + 23,350 x - 5,250 x2 con un R2 = 98,40 % y Y = 17,535 + 7,576 x - 2,08 x2 con un R2 = 97,61 %. Por otra parte, la masa seca de ramas se vio afectada por la interacción. Las variables masa seca foliar, porcentaje de cenizas, extracto etéreo, fibra cruda, materia orgánica, materia seca y proteína cruda no mostraron diferencias significativas para ninguno de los factores evaluados ni su interacción.

  14. "I like that He Always Shows Who He Is": The Perceptions and Experiences of Siblings with a Brother with Autism Spectrum Disorder

    Science.gov (United States)

    Petalas, Michael A.; Hastings, Richard P.; Nash, Susie; Dowey, Alan; Reilly, Deirdre

    2009-01-01

    Semi-structured interviews were used to explore the perceptions and experiences of eight typically developing siblings in middle childhood who had a brother with autism spectrum disorder (ASD). The interviews were analysed using interpretative phenomenological analysis (IPA). The analysis yielded five main themes: (i) siblings' perceptions of the…

  15. "My Brother Likes Meeting New People, but Don't Ask Him Any Direct Questions": Involving Adults with Autism plus Learning Disability in a Qualitative Research Project

    Science.gov (United States)

    Tozer, Rosemary; Atkin, Karl; Wenham, Aniela

    2014-01-01

    Adult siblings of people with autism and a learning disability have hitherto been largely overlooked by research, policy and practice in the UK. As part of a qualitative study focussing on adult siblings, we met twelve people with autism plus severe learning disability with their brother or sister. Individually tailored resources were used to make…

  16. Adolescent Siblings of Individuals with and without Intellectual and Developmental Disabilities: Self-Reported Empathy and Feelings about Their Brothers and Sisters

    Science.gov (United States)

    Shivers, Carolyn M.; Dykens, Elisabeth M.

    2017-01-01

    Siblings of brothers or sisters with intellectual and developmental disabilities (IDD) are important but understudied family members. As many previous studies have relied on parent report of sibling outcomes, the use of sibling self-report is an important addition to the research. This study assessed the feelings of adolescent siblings toward…

  17. Surgical Treatment for Epstein-Barr Virus Otomastoiditis Complicated by Facial Nerve Paralysis: A Case Report of Two Young Brothers and Review of Literature

    NARCIS (Netherlands)

    Eeten, E. van; Faber, H.T.; Kunst, D.

    2017-01-01

    We report the case of two young brothers with Epstein-Barr virus (EBV) otomastoiditis complicated by a facial nerve paralysis. The boys, aged 7 months (patient A) and 2 years and 8 months (patient B), were diagnosed with a facial nerve paralysis House-Brackmann (HB) grade IV (A) and V (B). After

  18. 'A Strange Mixture of Caring and Corruption': Residential Care in Christian Brothers Orphanages and Industrial Schools during Their Last Phase, 1940s to 1960s.

    Science.gov (United States)

    Coldrey, Barry

    2000-01-01

    Explores the two Christian Brothers religious orders of the Roman Catholic Church. Focuses on the Irish Congregation that has been controversial, specifically in its residential care for neglected, orphaned, and delinquent children. States that allegations of physical, sexual, and emotional abuse has been reported in their institutions. (CMK)

  19. Samuel Alderman Lomas (1838-1901) the man with two gravestones, his brother Muscot Atkin Lomas (1840-1907) and their lives in Victorian asylums.

    Science.gov (United States)

    Hilton, Claire; Hilton, Benjamin

    2009-05-01

    Samuel Alderman Lomas died in the Hertfordshire County Asylum, Hill End, St Albans in 1901. He was buried in the asylum cemetery where two gravestones bear his name. This paper traces his life history and that of his brother Muscot Atkin Lomas. Both were classed as idiots in Victorian society and spent most of their lives -- from childhood until death -- in asylums.

  20. Recurrent episodes of myoglobinuria, mental retardation and seizures but no hemolysis in two brothers with phosphoglycerate kinase deficiency.

    Science.gov (United States)

    Coppens, Sandra; Koralkova, Pavla; Aeby, Alec; Mojzikova, Renata; Deconinck, Nicolas; Kadhim, Hazim; van Wijk, Richard

    2016-03-01

    We report two brothers with mild intellectual deficiency, exercise intolerance, rhabdomyolysis, seizures and no hemolysis. Phosphoglycerate kinase (PGK) activity was strongly decreased in their red blood cells. Subsequent molecular analysis of PGK1 revealed hemizygosity for a novel mutation c.756 + 3A > G, in intron 7. Analysis of the effect of this mutation on pre-mRNA processing demonstrated markedly decreased levels of normal PGK1 mRNA. In addition, the c.756 + 3A > G change resulted in abnormally spliced transcripts. If translated, these transcripts mostly encode for C-terminally truncated proteins. The consequences of the c.756 + 3A > G mutation is discussed, as well as the genotype-to-phenotype correlation with regard to previously described mutations (PGK Fukuroi and PGK Antwerp), which also result in C-terminal truncated proteins. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Cognitive ability in young adulthood and risk of dementia in a cohort of Danish men, brothers, and twins

    DEFF Research Database (Denmark)

    Osler, Merete; Christensen, Gunhild T.; Garde, Ellen

    2017-01-01

    INTRODUCTION: We examined the association between cognitive ability in young adulthood and dementia in Danish men, brothers, and male twins. METHODS: In total, 666,986 men born between 1939 and 1959 were identified for dementia diagnosis in national registries from 1969 to 2016. The association...... between cognitive ability from draft board examination and dementia was examined using Cox regression. RESULTS: During a 44-year follow-up, 6416 (0.96%) men developed dementia, 1760 (0.26%) and 970 (0.15%) of which were classified as Alzheimer's and vascular dementia, respectively. Low cognitive ability...... was associated with increased risk of dementia (hazard ratio [HR]per SD decrease 1.33 [95% confidence interval {CI} = 1.30-1.35]) with the strongest associations for vascular dementia (HRper SD decrease 1.47 [95% CI = 1.31-1.56]) and a weaker for Alzheimer's disease (HRper SD decrease 1.07 [95% CI = 1...

  2. A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty

    DEFF Research Database (Denmark)

    Känsäkoski, Johanna; Raivio, Taneli; Juul, Anders

    2015-01-01

    BACKGROUND: Idiopathic central precocious puberty (ICPP) results from the premature reactivation of the hypothalamic-pituitary-gonadal axis leading to development of secondary sexual characteristics prior to 8 y in girls or 9 y in boys. Since the initial discovery of mutations in the maternally...... imprinted MKRN3 gene in 2013, several case reports have described mutations in this gene in ICPP patients from different populations, highlighting the importance of MKRN3 as a regulator of pubertal onset. METHODS: We screened 29 Danish girls with ICPP for mutations in MKRN3. Expression of MKRN3 in human...... hypothalamic complementary DNA (cDNA) was investigated by PCR. RESULTS: One paternally inherited rare variant, c.1034G>A (p.Arg345His), was identified in one girl with ICPP and in her brother with early puberty. The variant is predicted to be deleterious by three different in silico prediction programs...

  3. Gabriel García Márquez's «Eréndira» and the Brothers Grimm

    Directory of Open Access Journals (Sweden)

    Joel Hancock

    1978-08-01

    Full Text Available García Márquez's long story «La increíble y triste historia de la Cándida Eréndira y de su abuela desalmada» is studied in the light of the structures and themes of the fairy tale, particularly of the type collected by the Grimm brothers. Dimensions of special interest are the organizational framework of the narrative, the portrayal of characters, and certain motifs, all of which are strongly reminiscent of Grimm's Fairy Tales . These elements are examined as representative of those morphologies which Vladimir Propp delineates for the genre of the fairy tale in his Morphology of the Folktale .

  4. brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish

    Science.gov (United States)

    Bergeron, Sadie A.; Tyurina, Oksana V.; Miller, Emily; Bagas, Andrea; Karlstrom, Rolf O.

    2011-01-01

    The transmembrane protein Brother of Cdo (Boc) has been implicated in Shh-mediated commissural axon guidance, and can both positively and negatively regulate Hedgehog (Hh) target gene transcription, however, little is known about in vivo requirements for Boc during vertebrate embryogenesis. The zebrafish umleitung (umlty54) mutant was identified by defects in retinotectal axon projections. Here, we show that the uml locus encodes Boc and that Boc function is cell-autonomously required for Hh-mediated neural patterning. Our phenotypic analysis suggests that Boc is required as a positive regulator of Hh signaling in the spinal cord, hypothalamus, pituitary, somites and upper jaw, but that Boc might negatively regulate Hh signals in the lower jaw. This study reveals a role for Boc in ventral CNS cells that receive high levels of Hh and uncovers previously unknown roles for Boc in vertebrate embryogenesis. PMID:21115611

  5. A novel AVPR2 splice site mutation leads to partial X-linked nephrogenic diabetes insipidus in two brothers.

    Science.gov (United States)

    Schernthaner-Reiter, Marie Helene; Adams, David; Trivellin, Giampaolo; Ramnitz, Mary Scott; Raygada, Margarita; Golas, Gretchen; Faucz, Fabio R; Nilsson, Ola; Nella, Aikaterini A; Dileepan, Kavitha; Lodish, Maya; Lee, Paul; Tifft, Cynthia; Markello, Thomas; Gahl, William; Stratakis, Constantine A

    2016-05-01

    X-linked nephrogenic diabetes insipidus (NDI, OMIM#304800) is caused by mutations in the arginine vasopressin (AVP, OMIM*192340) receptor type 2 (AVPR2, OMIM*300538) gene. A 20-month-old boy and his 8-year-old brother presented with polyuria, polydipsia, and failure to thrive. Both boys demonstrated partial DDAVP (1-desamino-8-D AVP or desmopressin) responses; thus, NDI diagnosis was delayed. While routine sequencing of AVPR2 showed a potential splice site variant, it was not until exome sequencing confirmed the AVPR2 splice site variant and did not reveal any more likely candidates that the patients' diagnosis was made and proper treatment was instituted. Both patients were hemizygous for two AVPR2 variants predicted in silico to affect AVPR2 messenger RNA (mRNA) splicing. A minigene assay revealed that the novel AVPR2 c.276A>G mutation creates a novel splice acceptor site leading to 5' truncation of AVPR2 exon 2 in HEK293 human kidney cells. Both patients have been treated with high-dose DDAVP with a remarkable improvement of their symptoms and accelerated linear growth and weight gain. We present here a unique case of partial X-linked NDI due to an AVPR2 splice site mutation; patients with diabetes insipidus of unknown etiology may harbor splice site mutations that are initially underestimated in their pathogenicity on sequence analysis. • X-linked nephrogenic diabetes insipidus is caused by AVPR2 mutations, and disease severity can vary depending on the functional effect of the mutation. What is New: • We demonstrate here that a splice site mutation in AVPR2 leads to partial X-linked NDI in two brothers. • Treatment with high-dose DDAVP led to improvement of polyuria and polydipsia, weight gain, and growth.

  6. Efeito de doses de metribuzin no crescimento e na conversão da energia solar em plantas de soja (Glycine max (L . merrill Effect of metribuzin doses on the growth and solar energy conversion in soybean (Glycine max (L. merrill plants

    Directory of Open Access Journals (Sweden)

    P. J. Silva Neto

    1991-01-01

    Full Text Available O crescimento e a eficiência na conversão da energia solar foram estudados em soja (Glycine max (L. Merri ll, cv. 'Uberaba', cultivada em condições de campo, sob quatro doses de metribuzin (0, 0,35; 0,70 e 1,05 kg i.a.ha-1. O valor máximo da conversão da energia solar foi de 0,75%, para as plantas cultiva das na maior dose do herbicida. Os valores da conversão da energia solar média durante o ciclo da cultura foram 0,32 ; 0,31 ; 0,32 e 0,33%. em ordem crescente de dose do metribuzin. De modo geral, na fase vegetativa as plantas controle apresentaram valores inferiores em todos os valores de crescimento determinados, superando as tratadas com metribuzin somente na fase reprodutiva, mostrando que no período crítico de competição o dano causado pelas plantas daninhas é maior que a possível fitotoxicida de causada pelo metribuzin.Growth analysis and evaluation of solar energy conversion in soybean (Glycine max (L. Merrill, Uberaba unver field conditions and four doses of metribuzin (0,0;0,35; 0,70 and 1,05 kg i.a.ha-1 were performed in this study. Maximum solar energy conversion was 0,75% for pla nts tre ate d wit h 1,05 kg i.a.ha -1 metribuzin. The aver age of solar energy conversion throughout the entire crop cycle were 0,32, 0,31 , 0,32 and 0,33% for the increasing metribuzin doses. In general, the control showed lower figures for all growth values studied than the treated during the vegetative phase. During the reproductive phase, however, they surpassed those tre ated with metribuzin, showing that in the critical period of competition weeds were more harmful than the phytotoxicity produced by metribuzin.

  7. « Nous sommes tous frères ». Les valeurs des Elephants de Brother, club de baseball professionnel à Taiwan “We are all Brothers”. The Values of Brother Elephants, professional baseball club in Taiwan

    Directory of Open Access Journals (Sweden)

    Jérôme Soldani

    2013-06-01

    Full Text Available À Taiwan, où le baseball est considéré comme le « sport national », les équipes professionnelles sont la propriété de grandes firmes locales et ne sont pas formellement attachées à une municipalité. Ce sont elles-mêmes de petites entreprises qui proposent, en archétype de société, un mode de fonctionnement interne qui repose sur des valeurs autour desquelles se fédèrent leurs supporters. Basée sur une enquête ethnographique de douze mois, notamment au sein de la formation professionnelle des Elephants de Brother, cette contribution montrera comment celle-ci se donne à voir comme une entreprise structurée autour de valeurs morales entendues comme « traditionnelles » et dont les joueurs de l’équipe sont érigés en parangons. Le modèle d’une famille unie et strictement hiérarchisée est mis en exergue par les propriétaires du club et son iconographie. Mais ces représentations se heurtent à la réalité de la pratique quotidienne et aux affaires de corruption qui sapent régulièrement l’image de la ligue professionnelle taiwanaise.In Taiwan, where baseball is considered as the national sport, professional teams are owned by large local firms and are not formally attached to a municipality. They are themselves small companies offering an archetypal society, whose mode of internal operations are based on values around which to unite their fans. Based on an ethnographic study of twelve months, particularly among the professional team of Brother Elephants, this contribution will show how it is to be seen as an enterprise structured around moral values understood as traditional and whose players are established as paragons. The model of a united family and strictly hierarchical is highlighted by the owners of the club and its iconography. But these representations are faced with the reality of daily practice and corruption that regularly undermine the image of the Taiwanese professional league.

  8. Ação do Agrostemin sobre a altura e o número de folhas de plantas de soja (Glycine max L. MERRILL cv. IAC-8 Effects of Agrostemmin on number of leaves and height of soybean plants

    Directory of Open Access Journals (Sweden)

    A.A.H. Fernandes

    1993-05-01

    Full Text Available O presente estudo teve por finalidade avaliar o efeito de um estimulante vegetal, o Agrostemin, sobre a altura e o número de folhas das plantas de soja (Glycine max L. MERRILL cv. IAC-8. O experimento foi conduzido em casa de vegetação. Foram estudados seis tratamentos, correspondentes as seguintes dosagens, épocas e formas de aplicação: testemunha (T1; 0,125g Agrostemin/l00g sementes (T2; 0,125g Agrostemin/100g semente e pulverização foliar à 333 ppm (T3; 0,125g Agrostemin/l00g sementes e pulverização foliar à 500 ppm (T4; pulverização foliar à 333 ppm (T5 e pulverização foliar à 500 ppm (T6. Realizaram-se três coletas de plantas, com intervalo de 14 dias. O experimento foi em delineamento inteiramente casualizado, utilizando-se duas análises de variância com desdobramento em efeitos de regressão. Através dos resultados obtidos concluiu-se que o Agrostemin quando aplicado via semente (T2 ou via foliar à 500 ppm (T6, aumentou a altura e o número de folhas. Ao aplicar o produto via semente mais via foliar à 500 ppm (T4, estas medidas diminuiram.A greenhouse experiment was conducted to evaluate the effects of Agrostemmin (plant stimulant on height and number of leaves of soybean plants (Glycine max L Merril cv. IAC-8. Six treatments were studied: check (T1; 0,125g Agrostemmin/l00g seed (T2; 0,125g Agrostemmin/100 seed and foliar spraying 333 ppm (T3; 0,125g Agrostemmin/l00g seed and foliar spraying 500 ppm (T4; foliar spraying 333 ppm (T5 and foliar spraying 500 ppm (T6. Three samplings were made at 14 day intervals. The experimental layout was completely randomized, using two variance, testing regression effects. Agrostemmin applied to the seed (T2 or sprayed on the leaves at the rate of 500 ppm (T6 increased height and number of leaves of soybean, whereas the combination of Agrostemmin applied to the seeds and sprayed at 500 ppm (T4 decreased those values.

  9. Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: A 'Big Brother' evaluation

    International Nuclear Information System (INIS)

    Steenbakkers, Roel J.H.M.; Duppen, Joop C.; Fitton, Isabelle; Deurloo, Kirsten E.I.; Zijp, Lambert; Uitterhoeve, Apollonia L.J.; Rodrigus, Patrick T.R.; Kramer, Gijsbert W.P.; Bussink, Johan; Jaeger, Katrien De; Belderbos, Jose S.A.; Hart, Augustinus A.M.; Nowak, Peter J.C.M.; Herk, Marcel van; Rasch, Coen R.N.

    2005-01-01

    Background and purpose: To evaluate the process of target volume delineation in lung cancer for optimization of imaging, delineation protocol and delineation software. Patients and methods: Eleven radiation oncologists (observers) from five different institutions delineated the Gross Tumor Volume (GTV) including positive lymph nodes of 22 lung cancer patients (stages I-IIIB) on CT only. All radiation oncologist-computer interactions were recorded with a tool called 'Big Brother'. For each radiation oncologist and patient the following issues were analyzed: delineation time, number of delineated points and corrections, zoom levels, level and window (L/W) settings, CT slice changes, use of side windows (coronal and sagittal) and software button use. Results: The mean delineation time per GTV was 16 min (SD 10 min). The mean delineation time for lymph node positive patients was on average 3 min larger (P=0.02) than for lymph node negative patients. Many corrections (55%) were due to L/W change (e.g. delineating in mediastinum L/W and then correcting in lung L/W). For the lymph node region, a relatively large number of corrections was found (3.7 corr/cm 2 ), indicating that it was difficult to delineate lymph nodes. For the tumor-atelectasis region, a relative small number of corrections was found (1.0 corr/cm 2 ), indicating that including or excluding atelectasis into the GTV was a clinical decision. Inappropriate use of L/W settings was frequently found (e.g. 46% of all delineated points in the tumor-lung region were delineated in mediastinum L/W settings). Despite a large observer variation in cranial and caudal direction of 0.72 cm (1 SD), the coronal and sagittal side windows were not used in 45 and 60% of the cases, respectively. For the more difficult cases, observer variation was smaller when the coronal and sagittal side windows were used. Conclusions: With the 'Big Brother' tool a method was developed to trace the delineation process. The differences between

  10. Congenital hypogonadotropic hypogonadism due to GnRH receptor mutations in three brothers reveal sites affecting conformation and coupling.

    Directory of Open Access Journals (Sweden)

    Javier A Tello

    Full Text Available Congenital hypogonadotropic hypogonadism (CHH is characterized by low gonadotropins and failure to progress normally through puberty. Mutations in the gene encoding the GnRH receptor (GNRHR1 result in CHH when present as compound heterozygous or homozygous inactivating mutations. This study identifies and characterizes the properties of two novel GNRHR1 mutations in a family in which three brothers display normosmic CHH while their sister was unaffected. Molecular analysis in the proband and the affected brothers revealed two novel non-synonymous missense GNRHR1 mutations, present in a compound heterozygous state, whereas their unaffected parents possessed only one inactivating mutation, demonstrating the autosomal recessive transmission in this kindred and excluding X-linked inheritance equivocally suggested by the initial pedigree analysis. The first mutation at c.845 C>G introduces an Arg substitution for the conserved Pro 282 in transmembrane domain (TMD 6. The Pro282Arg mutant is unable to bind radiolabeled GnRH analogue. As this conserved residue is important in receptor conformation, it is likely that the mutation perturbs the binding pocket and affects trafficking to the cell surface. The second mutation at c.968 A>G introduces a Cys substitution for Tyr 323 in the functionally crucial N/DPxxY motif in TMD 7. The Tyr323Cys mutant has an increased GnRH binding affinity but reduced receptor expression at the plasma membrane and impaired G protein-coupling. Inositol phosphate accumulation assays demonstrated absent and impaired Gα(q/11 signal transduction by Pro282Arg and Tyr323Cys mutants, respectively. Pretreatment with the membrane permeant GnRHR antagonist NBI-42902, which rescues cell surface expression of many GNRHR1 mutants, significantly increased the levels of radioligand binding and intracellular signaling of the Tyr323Cys mutant but not Pro282Arg. Immunocytochemistry confirmed that both mutants are present on the cell membrane

  11. Congenital Hypogonadotropic Hypogonadism Due to GNRH Receptor Mutations in Three Brothers Reveal Sites Affecting Conformation and Coupling

    Science.gov (United States)

    Tello, Javier A.; Newton, Claire L.; Bouligand, Jerome; Guiochon-Mantel, Anne

    2012-01-01

    Congenital hypogonadotropic hypogonadism (CHH) is characterized by low gonadotropins and failure to progress normally through puberty. Mutations in the gene encoding the GnRH receptor (GNRHR1) result in CHH when present as compound heterozygous or homozygous inactivating mutations. This study identifies and characterizes the properties of two novel GNRHR1 mutations in a family in which three brothers display normosmic CHH while their sister was unaffected. Molecular analysis in the proband and the affected brothers revealed two novel non-synonymous missense GNRHR1 mutations, present in a compound heterozygous state, whereas their unaffected parents possessed only one inactivating mutation, demonstrating the autosomal recessive transmission in this kindred and excluding X-linked inheritance equivocally suggested by the initial pedigree analysis. The first mutation at c.845 C>G introduces an Arg substitution for the conserved Pro 282 in transmembrane domain (TMD) 6. The Pro282Arg mutant is unable to bind radiolabeled GnRH analogue. As this conserved residue is important in receptor conformation, it is likely that the mutation perturbs the binding pocket and affects trafficking to the cell surface. The second mutation at c.968 A>G introduces a Cys substitution for Tyr 323 in the functionally crucial N/DPxxY motif in TMD 7. The Tyr323Cys mutant has an increased GnRH binding affinity but reduced receptor expression at the plasma membrane and impaired G protein-coupling. Inositol phosphate accumulation assays demonstrated absent and impaired Gαq/11 signal transduction by Pro282Arg and Tyr323Cys mutants, respectively. Pretreatment with the membrane permeant GnRHR antagonist NBI-42902, which rescues cell surface expression of many GNRHR1 mutants, significantly increased the levels of radioligand binding and intracellular signaling of the Tyr323Cys mutant but not Pro282Arg. Immunocytochemistry confirmed that both mutants are present on the cell membrane albeit at low

  12. Comedia del valor de las letras y las armas: New Light on the Story of Captive Captain and his Brothers (DQ 1, 37-45

    Directory of Open Access Journals (Sweden)

    Clark Colahan

    2015-12-01

    Full Text Available The tale of the captive captain, Ruy Pérez de Viedma, and his brothers, as well as Don Quixote’s discourse on arms and letters which serves as its prologue, have been well studied, but a model combining both parts of this thematic unit found in the first part of Don Quixote has not been previously identified. The anonymous late-sixteenth-century play Comedia del valor de las letras y las armas, here studied as a source for the first time, may well have been known to Cervantes and provides extensive parallels of theme and characterization to Cervantes’ treatment of both Renaissance discourse on preserving peace and the folktale of three brothers and their respective professions. It brings into sharp focus that these chapters resolve the debate between arms and letters in favor of a third element, social power and money.

  13. Influência de abelhas africanizadas na concentração de açúcares no néctar de soja (Glycine max L. Merrill var. Coodetec 207 = Influence of africanized honeybees on sugar concentration in the nectar of soybean (Glycine max L. Merrill var. Coodetec 207

    Directory of Open Access Journals (Sweden)

    Eloi Machado Alves

    2010-04-01

    Full Text Available O objetivo foi avaliar a concentração de açúcares no néctar de soja (Glycine max L. Merrill em áreas com ou sem a presença de abelhas Apis mellifera L. Foi utilizada a variedade Coodetec 207 em quatro tratamentos: área de 24 m2 coberta com colônia de abelhas africanizadas em seu interior; área semicoberta com livre acesso para insetos visitantes; área livre e área coberta sem abelhas. As flores foram coletadas durante três dias, a cada 2h. e a concentração dos açúcares totais por flor foi determinada por espectrofotometria. A área coberta com abelha apresentou maior concentração de açúcares totais em relação à área coberta sem abelhas e livre, contudo, aconcentração de açúcares totais na área livre não diferiu da concentração observada na área coberta sem abelhas. Houve redução na concentração média de sacarose na área livre, diferindo das concentrações nas demais áreas. A concentração média de glicose não diferiu entre os tratamentos, enquanto que a de frutose não apresentou diferença entre as áreas cobertas com abelhas, semicoberta e livre. A variedade Coodetec 207 da soja apresentou maior concentração total de açúcares e de frutose nas áreas cobertas com abelhas. Contudo, a presença de Apis mellifera não interferiu nesta concentração de açúcares no néctar das flores de soja desta variedade.This research was carried out to evaluate the sugar concentration in soybean nectar in areas with Africanized honeybee colonies. The var. Coodetec 207 was used in four treatments: 24 m2 covered area with Africanized honeybee colony inside, semi-covered area for free insect visitation, uncovered area, and covered area without insect visitation. Flowers were harvested for three days at two-hour intervals, and the total sugar concentration per flower was determined by spectrophotometry. The covered area with Africanized honeybee colony presented higher sugar concentration than the covered area

  14. Non-marfan idiopathic medionecrosis (cystic medial necrosis) presenting with multiple visceral artery aneurysms and diffuse connective tissue fragility: Two brothers

    International Nuclear Information System (INIS)

    Kubota, Jun; Tsunemura, Mami; Amano, Shigeko; Tokizawa, Shigemi; Oowada, Susumu; Shinkai, Hiroko; Maehara, Yasunobu; Endo, Keigo

    1997-01-01

    Two brothers with multiple visceral artery aneurysms or dilatations and diffuse connective tissue fragility who did not have clinical features of Marfan syndrome are reported. One presented with retroperitoneal hemorrhage during angiography, and idiopathic medionecrosis was proved by resection of the aneurysms. These cases belong to the heterogeneous group of Marfan syndrome. The angiographical features (multiple dilation of visceral arteries) suggests fragility of connective tissue and is predictive of hazards during and after a catheterization and operation

  15. THE EVANGELICAL AS THE NATIVE IN THE “BROTHERS KARAMAZOV” AND IN “A WRITER’S DIARY” (1876–1877) BY FYODOR DOSTOEVSKY

    OpenAIRE

    Elena A. Fedorova

    2015-01-01

    The article identifi es the reasons for Fyodor Dostoevsky’s appeal to the traditions of Old Russian literature in “A Writer’s Diary” during the Russian-Turkish war. One of the main reasons is seeking for national foundations of Russian spirituality. The writer learned the world of medieval literacy getting acquainted with hagiography, walking, spiritual eloquence. Later Dostoevsky reverted to the Old Russian monuments in the course of his work on the novel “The Brothers Kara...

  16. [Sense of coherence and ways of coping in the relationship with brother or sister in healthy siblings of mentally ill persons].

    Science.gov (United States)

    Osuchowska-Kościjańska, Anna; Charzyńska, Katarzyna; Chadzyńska, Małgorzata; Drozdzyńska, Anna; Kasperek-Zimowska, Beata; Bednarek, Agata; Sawicka, Maryla

    2014-01-01

    The aim of the present study was to investigate sense of coherence in healthy siblings of persons suffering from schizophrenia as well as their ways of coping in the relationship with ill brother or sister. 40 healthy brothers and sisters of persons with ICD- 10 diagnosis of F20 to F29 participated in the present study. Orientation to Life Scale (SOC- 29) was used to assess sense of coherence and Ways of Coping with Stress questionnaire (SRSS) was used to examine stress coping strategies. Mean global score of siblings of persons with schizophrenia was 111 points. Subjects used coping strategies focused on problem significantly more often than those focused on emotions. Therapeutic work with healthy siblings should focus on strengthening sense of personal competence, development of personal resources and different ways of coping with stress, investigation of emotions that healthy siblings experience in the relationship with ill brother or sister as well as supporting the process of accepting changes in the relationship with the ill sibling.

  17. Three years follow-up of pamidronate therapy in two brothers with osteoporosis-pseudoglioma syndrome (OPPG) carrying an LRP5 mutation.

    Science.gov (United States)

    Barros, Elizabete Ribeiro; Dias da Silva, Magnus R; Kunii, Ilda S; Lazaretti-Castro, Marise

    2008-08-01

    Osteoporosis-pseudoglioma (OPPG) is a rare syndrome characterized by severe osteoporosis and ocular defects caused by homozygotic inactivation mutations in the LRP5 gene. Bisphosphonate has been demonstrated to improve bone mineral density (BMD) in children with OPPG. We present here a 3 years follow-up of two brothers with OPPG carrying a novel mutation in the LRP5 gene, who were treated with intravenous pamidronate. We looked for a mutation in the LRP5 gene in two brothers (12 and 4 years old) with clinical features of OPPG (blindness, low BMD and fragility fractures) and in their consanguineous parents to confirm the diagnosis of OPPG. The patients were treated with bisphosphonate for 3 years. They received 1 mg/kg/day of pamidronate for 2 consecutive days, every 3 months during the first year, and every 4 months in subsequent years. Calcium, phosphorus, total alkaline phosphatase, parathyroid hormone, hepatic transaminases, creatinine and hemogram tests were performed before each infusion. Bone densitometry was performed at baseline and at the end of the follow-up. The affected brothers carry a missense mutation in the third codon of exon 8 (AAT-->ATT) that led to the exchange of an asparagine for an isoleucine (N531I). Both parents were found to be heterozygous for this mutation. The intravenous pamidronate therapy was safe for up to 3 years of use. Moreover, increased BMD and decreased fracture rate were observed in our patients with OPPG.

  18. A novel homozygous AP4B1 mutation in two brothers with AP-4 deficiency syndrome and ocular anomalies.

    Science.gov (United States)

    Accogli, Andrea; Hamdan, Fadi F; Poulin, Chantal; Nassif, Christina; Rouleau, Guy A; Michaud, Jacques L; Srour, Myriam

    2018-04-01

    Adaptor protein complex-4 (AP-4) is a heterotetrameric protein complex which plays a key role in vesicle trafficking in neurons. Mutations in genes affecting different subunits of AP-4, including AP4B1, AP4E1, AP4S1, and AP4M1, have been recently associated with an autosomal recessive phenotype, consisting of spastic tetraplegia, and intellectual disability (ID). The overlapping clinical picture among individuals carrying mutations in any of these genes has prompted the terms "AP-4 deficiency syndrome" for this clinically recognizable phenotype. Using whole-exome sequencing, we identified a novel homozygous mutation (c.991C>T, p.Q331*, NM_006594.4) in AP4B1 in two siblings from a consanguineous Pakistani couple, who presented with severe ID, progressive spastic tetraplegia, epilepsy, and microcephaly. Sanger sequencing confirmed the mutation was homozygous in the siblings and heterozygous in the parents. Similar to previously reported individuals with AP4B1 mutations, brain MRI revealed ventriculomegaly and white matter loss. Interestingly, in addition to the typical facial gestalt reported in other AP-4 deficiency cases, the older brother presented with congenital left Horner syndrome, bilateral optic nerve atrophy and cataract, which have not been previously reported in this condition. In summary, we report a novel AP4B1 homozygous mutation in two siblings and review the phenotype of AP-4 deficiency, speculating on a possible role of AP-4 complex in eye development. © 2018 Wiley Periodicals, Inc.

  19. A dictionary without definitions: romanticist science in the production and presentation of the Grimm brothers' German dictionary, 1838-1863.

    Science.gov (United States)

    Kistner, Kelly

    2014-12-01

    Between 1838 and 1863 the Grimm brothers led a collaborative research project to create a new kind of dictionary documenting the history of the German language. They imagined the work would present a scientific account of linguistic cohesiveness and strengthen German unity. However, their dictionary volumes (most of which were arranged and written by Jacob Grimm) would be variously criticized for their idiosyncratic character and ultimately seen as a poor, and even prejudicial, piece of scholarship. This paper argues that such criticisms may reflect a misunderstanding of the dictionary. I claim it can be best understood as an artifact of romanticist science and its epistemological privileging of subjective perception coupled with a deeply-held faith in inter-subjective congruence. Thus situated, it is a rare and detailed case of Romantic ideas and ideals applied to the scientific study of social artifacts. Moreover, the dictionary's organization, reception, and legacy provide insights into the changing landscape of scientific practice in Germany, showcasing the difficulties of implementing a romanticist vision of science amidst widening gaps between the public and professionals, generalists and specialists.

  20. Hasil Rancang Bangun Sistem ERP dengan SDLC Model Waterfall: Studi Kasus Sistem Inventori PT Pan Brothers, Tbk.

    Directory of Open Access Journals (Sweden)

    Harijanto Pangestu

    2012-12-01

    Full Text Available Competition in the business world effects the use of information technology. To achieve competitive advantage in the global competition, PT Pan Brothers, Tbk. should establish an integrated information system based on ERP (Enterprise Resource Planning. With the ERP system, information will be accurate and up-todate to support strategic decision making. It takes conscientious planning in building the ERP system. Management information systems development projects have a very important role. One determining component is how to choose and use appropriate information systems development method. SDLC (system development life cycle is growing very rapidly along with the development of information technology. It is necessary to choose the right SDLC in building an integrated system based on ERP. Each SDLC models has advantages and disadvantages. SDLC models will only be optimal if used according to the situation and conditions. Waterfall model provides clear deliverables and milestones, good documentation, easy to understand, easy to implement, emphasizes on good procedural workmanship (precoding design. Some of its weaknesses are difficult to integrate risk management, high cost change documents, high administrative costs, often late completion thus.To avoid them, there should be a well-planned project management and steps properly so it can be on time and will not exceed budget.

  1. Columbia River wildlife mitigation habitat evaluation procedures report: Scotch Creek Wildlife Area, Berg Brothers, and Douglas County pygmy rabbit projects

    International Nuclear Information System (INIS)

    Ashley, P.R.; Ratassepp, J.; Berger, M.; Judd, S.L.

    1997-01-01

    This Habitat Evaluation Procedure study was conducted to determine baseline habitat units (HUs) on the Scotch Creek, Mineral Hill, Pogue Mountain, Chesaw and Tunk Valley Habitat Areas (collectively known as the Scotch Creek Wildlife Area) in Okanogan County, Sagebrush Flat and the Dormaler property in Douglas County, and the Berg Brothers ranch located in Okanogan County within the Colville Reservation. A HEP team comprised of individuals from the Washington Department of Fish and Wildlife, the Confederated Tribes of the Colville Reservation, and the Natural Resources Conservation Service (Appendix A) conducted baseline habitat surveys using the following HEP evaluation species: mule deer (Odocoileus hemionus), sharp-tailed grouse (Tympanuchus phasianellus), pygmy rabbit (Brachylagus idahoensis), white-tailed deer (Odocoileus virginiana), mink (Mustela vison), Canada goose (Branta canadensis), downy woodpecker (Picoides pubescens), Lewis woodpecker (Melanerpes lewis), and Yellow warbler (Dendroica petechia). Results of the HEP analysis are listed below. General ratings (poor, marginal, fair, etc.,) are described in Appendix B. Mule deer habitat was marginal lacking diversity and quantify of suitable browse species. Sharp-tailed grouse habitat was marginal lacking residual nesting cover and suitable winter habitat Pygmy rabbit habitat was in fair condition except for the Dormaier property which was rated marginal due to excessive shrub canopy closure at some sites. This report is an analysis of baseline habitat conditions on mitigation project lands and provides estimated habitat units for mitigation crediting purposes. In addition, information from this document could be used by wildlife habitat managers to develop management strategies for specific project sites

  2. A tragédia da impossibilidade do evento: Os Maias; o Big Brother e a pedagogia dos media

    Directory of Open Access Journals (Sweden)

    Orlando Grossegesse

    2010-01-01

    Full Text Available O romance Os Maias (1888 de Eça de Queiroz pertence ao cânone da Literatura Portuguesa. Questionando a leitura integral de textos literários no Ensino Secundário, a definição de Os Maias no sistema sócio-comunicativo da época como romance de conversação leva à descoberta do seu carácter dilemático numa sociedade dos média. No cerne desta abordagem está uma reinterpretação do incesto, evento que irrompe na vida social da alta sociedade lisboeta representada no romance. Esta representação é comparada ao Big Brother, levando a uma crítica da cultura que também diz respeito à actualidade. The novel Os Maias (1888, by Eça de Queiroz, belongs to the canons of Portuguese literature. Questioning the integral reading of literary texts in secondary school education, the definition of Os Maias in the sociocommunicative system of the time as a conversation novel highlights its dilemma in the media society. At the bottom of this approach lies the reinterpretation of incest, an event that bursts into the social life of Lisbon high society represented in the novel. This representation is compared with “Big Brother”, leading to a critique of culture that is also related to current times.

  3. Columbia River Wildlife Mitigation Habitat Evaluation Procedures Report / Scotch Creek Wildlife Area, Berg Brothers, and Douglas County Pygmy Rabbit Projects.

    Energy Technology Data Exchange (ETDEWEB)

    Ashley, Paul R.

    1997-01-01

    This Habitat Evaluation Procedure study was conducted to determine baseline habitat units (HUs) on the Scotch Creek, Mineral Hill, Pogue Mountain, Chesaw and Tunk Valley Habitat Areas (collectively known as the Scotch Creek Wildlife Area) in Okanogan County, Sagebrush Flat and the Dormaler property in Douglas County, and the Berg Brothers ranch located in Okanogan County within the Colville Reservation. A HEP team comprised of individuals from the Washington Department of Fish and Wildlife, the Confederated Tribes of the Colville Reservation, and the Natural Resources Conservation Service (Appendix A) conducted baseline habitat surveys using the following HEP evaluation species: mule deer (Odocoileus hemionus), sharp-tailed grouse (Tympanuchus phasianellus), pygmy rabbit (Brachylagus idahoensis), white-tailed deer (Odocoileus virginiana), mink (Mustela vison), Canada goose (Branta canadensis), downy woodpecker (Picoides pubescens), Lewis woodpecker (Melanerpes lewis), and Yellow warbler (Dendroica petechia). Results of the HEP analysis are listed below. General ratings (poor, marginal, fair, etc.,) are described in Appendix B. Mule deer habitat was marginal lacking diversity and quantify of suitable browse species. Sharp-tailed grouse habitat was marginal lacking residual nesting cover and suitable winter habitat Pygmy rabbit habitat was in fair condition except for the Dormaier property which was rated marginal due to excessive shrub canopy closure at some sites. This report is an analysis of baseline habitat conditions on mitigation project lands and provides estimated habitat units for mitigation crediting purposes. In addition, information from this document could be used by wildlife habitat managers to develop management strategies for specific project sites.

  4. Big Brother Experiments with the Regional Climate Model COSMO-CLM in an Idealised Setup to Investigate Lateral Boundary Conditions

    Science.gov (United States)

    Leps, Nora; Brauch, Jennifer; Ahrens, Bodo

    2017-04-01

    Our work aims at improving the regional coupled atmosphere-ocean model system COSMO-CLM/NEMO for decadal prediction. We address the different restricting conditions of regional climate modelling: Lower boundary conditions of the atmospheric system in the form of the coupled ocean, initial conditions and lateral boundary conditions of the coupled ocean-atmosphere system. Lateral boundary conditions (LBCs) are known to be an issue in dynamical downscaling with limited area regional climate models, and many studies have investigated the LBCs with regard to, e.g., frequency or resolution of LBCs, position of the domain and spurious effects. By default, the formulation of the LBCs in CCLM is a Davies relaxation scheme, which introduces a sponge layer at the lateral boundaries of the domain to dampen reflection of waves produced in the limited area domain at the prescribed boundaries. With idealised studies, it is possible to investigate the performance of this LBC formulation in CCLM in detail. The used framework is that of "big brother experiments" (BBEs). In a BBE, a high resolution simulation is performed over a larger domain, then its output is filtered to represent coarse-grid input, which is used to drive a nested smaller domain on the same high resolution. The differences between the two simulations can directly be attributed to the LBCs. Such experiments were performed in an idealised setup of a zonal flow over flat terrain or idealised hills with varying domain positions. First experiments show that for these idealised flows the relaxation works well for lateral boundary data on a high spatial resolution for different temporal resolutions. Next we plan to perform simulations with filtered lateral boundary data that only contains large scale features of the flow as well as different settings of the relaxation procedure.

  5. Cerebrotendinous xanthomatosis: report of two Brazilian brothers Xantomatose cerebrotendínea: relato de dois irmãos brasileiros

    Directory of Open Access Journals (Sweden)

    Marcos Christiano Lange

    2004-12-01

    Full Text Available Cerebrotendinous xanthomatosis is a treatable rare autossomal recessive disease characterized by lipid storage secondary to a sterol 27-hydroxylase deficiency in the formation of cholic and chenodeoxycholic acids. We describe two Brazilian brothers with cognitive impairement and chronic diarrhea. One of them also presents bilateral cataracts. Neurological findings were progressive walking deficit, limb ataxia and pyramidal signs. Both patients had bilateral Achilles tendon xanthomata. Magnetic resonance image showed signal alterations in cerebellar hemispheres. We describe these cases with molecular genetic analysis confirming diagnosis and comparing with previous literature. The CYP27A1 gene study showed a C1187T mutation on exon 6.Xantomatose cerebrotendínea é doença autossômica recessiva tratável causada pelo acúmulo de lipídeos por deficiência da enzima 27-esterol hidroxilase na produção de ácido cólico e deoxicólico. Descrevemos dois irmãos brasileiros com dificuldade cognitiva e diarréia crônica. Um deles apresentava catarata bilateral. Os achados neurológicos foram dificuldade progressiva para deambular, ataxia de membros e sinais piramidais. Ambos tinham xantomas de tendão aquileu bilateralmente. O exame de ressonância magnética revelou áreas de sinal hiperintenso em ambos os hemisférios cerebelares. Descrevemos os casos com diagnóstico genético comparando-os com a literatura. O estudo do gene CYP27A1 demonstrou a mutação C1183T no exon 6.

  6. A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections.

    Science.gov (United States)

    Xu, Xiu; Xu, Qiong; Zhang, Ying; Zhang, Xiaodi; Cheng, Tianlin; Wu, Bingbing; Ding, Yanhua; Lu, Ping; Zheng, Jingjing; Zhang, Min; Qiu, Zilong; Yu, Xiang

    2012-08-21

    Autistic spectrum disorders (ASDs) are a family of neurodevelopmental disorders with strong genetic components. Recent studies have shown that copy number variations in dosage sensitive genes can contribute significantly to these disorders. One such gene is the transcription factor MECP2, whose loss of function in females results in Rett syndrome, while its duplication in males results in developmental delay and autism. Here, we identified a Chinese family with two brothers both inheriting a 2.2 Mb MECP2-containing duplication (151,369,305 - 153,589,577) from their mother. In addition, both brothers also had a 213.7 kb duplication on Chromosome 2, inherited from their father. The older brother also carried a 48.4 kb duplication on Chromosome 2 inherited from the mother, and a 8.2 kb deletion at 11q13.5 inherited from the father. Based on the published literature, MECP2 is the most autism-associated gene among the identified CNVs. Consistently, the boys displayed clinical features in common with other patients carrying MECP2 duplications, including intellectual disability, autism, lack of speech, slight hypotonia and unsteadiness of movement. They also had slight dysmorphic features including a depressed nose bridge, large ears and midface hypoplasia. Interestingly, they did not exhibit other clinical features commonly observed in American-European patients with MECP2 duplication, including recurrent respiratory infections and epilepsy. To our knowledge, this is the first identification and characterization of Chinese Han patients with MECP2-containing duplications. Further cases are required to determine if the above described clinical differences are due to individual variations or related to the genetic background of the patients.

  7. A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections

    Directory of Open Access Journals (Sweden)

    Xu Xiu

    2012-08-01

    Full Text Available Abstract Background Autistic spectrum disorders (ASDs are a family of neurodevelopmental disorders with strong genetic components. Recent studies have shown that copy number variations in dosage sensitive genes can contribute significantly to these disorders. One such gene is the transcription factor MECP2, whose loss of function in females results in Rett syndrome, while its duplication in males results in developmental delay and autism. Case presentation Here, we identified a Chinese family with two brothers both inheriting a 2.2 Mb MECP2-containing duplication (151,369,305 – 153,589,577 from their mother. In addition, both brothers also had a 213.7 kb duplication on Chromosome 2, inherited from their father. The older brother also carried a 48.4 kb duplication on Chromosome 2 inherited from the mother, and a 8.2 kb deletion at 11q13.5 inherited from the father. Based on the published literature, MECP2 is the most autism-associated gene among the identified CNVs. Consistently, the boys displayed clinical features in common with other patients carrying MECP2 duplications, including intellectual disability, autism, lack of speech, slight hypotonia and unsteadiness of movement. They also had slight dysmorphic features including a depressed nose bridge, large ears and midface hypoplasia. Interestingly, they did not exhibit other clinical features commonly observed in American-European patients with MECP2 duplication, including recurrent respiratory infections and epilepsy. Conclusions To our knowledge, this is the first identification and characterization of Chinese Han patients with MECP2-containing duplications. Further cases are required to determine if the above described clinical differences are due to individual variations or related to the genetic background of the patients.

  8. An incest case with three biological brothers as alleged fathers: Even 22 autosomal STR loci analysis would not suffice without the mother.

    Science.gov (United States)

    Canturk, Kemal Murat; Emre, Ramazan; Gurkan, Cemal; Komur, Ilhami; Muslumanoglu, Omer; Dogan, Muhammed

    2016-07-01

    Here, we report an incest paternity case involving three biological brothers as alleged fathers (AFs), their biological sister and her child that was investigated using the Investigator ESSplex Plus, AmpFLSTR Identifiler Plus/Investigator IDplex Plus and PowerPlex 16 kits. Initial duo paternity investigations using 15-loci autosomal short tandem repeat (STR) analyses failed to exclude any of the AFs. Despite the fact that one of the brothers, AF1, had a mismatch with the child at a single locus (D2S1338), the possibility of a single-step mutation could not be ruled out. When the number of autosomal STR loci analysed was increased to 22 without the inclusion of the mother, AF2 and AF3 still could not be excluded, since both of them again had no mismatches with the child. A breakthrough was possible only upon inclusion of the mother so that trio paternity investigations were carried out. This time AF1 and AF2 could be excluded at two loci (D2S1338 and D1S1656) and six loci (vWa, D1S1656, D12S391, FGA, PENTA E and PENTA D), respectively, and AF3 was then the only brother who could not be excluded from paternity. Subsequent statistical analyses suggested that AF3 could be the biological father of the child with a combined paternity index >100 billion and a probability of paternity >99.99999999%. These findings consolidate the fact that complex paternity cases such as those involving incest could benefit more from the inclusion of the mother than simply increasing the number of STR loci analysed. © The Author(s) 2015.

  9. Comparison between high-resolution climate simulations using single- and double-nesting approaches within the Big-Brother experimental protocol

    Science.gov (United States)

    Matte, Dominic; Laprise, René; Thériault, Julie Mireille

    2016-12-01

    Regional climate models (RCM) are widely used to downscale global climate models' (GCMs) simulations. As the resolution of RCM increases faster than that of GCM used for climate-change projections till the end of this century, the resolution jump will become an issue. Cascade with multiple nesting offers an approach to reach high resolution while keeping reasonable computational cost. Few studies have addressed whether the best results are obtained with the single- or multiple-nesting approaches. In this study the results obtained with single and double nesting are compared within the idealised "perfect model" framework of the Big-Brother Experiment. This method consists in first realizing a simulation, nicknamed the Big-Brother (BB) simulation, on a relatively large domain at the desired resolution, to serve as reference dataset. The BB results are then processed by a low-pass filter to emulate a coarse-resolution dataset to be used as LBC to drive further simulations, nicknamed the Little-Brother (LB) simulations, using an identical model formulation and resolution as the BB simulation. For the single nesting, the LB simulations are directly simulated, while for the double nesting a surrogate intermediate-resolution simulation is used. The study of the time-mean (stationary) component shows that little difference is noted between the single- and double-nesting approaches. The time-deviation (transient-eddy) component, however, shows important differences. The double-nesting approach weakly degrades the large scales but allows a significant reduction of the required domain size to allow adequate spin-up of fine-scale features. This results in an important saving in the computational cost.

  10. Adult onset supranuclear ophthalmoplegia, cerebellar ataxia, and neurogenic proximal muscle weakness in a brother and sister: another hexosaminidase A deficiency syndrome.

    Science.gov (United States)

    Harding, A E; Young, E P; Schon, F

    1987-01-01

    An Ashkenazi Jewish brother and sister developed progressive ataxia and proximal neurogenic muscle weakness, associated with supranuclear ophthalmoplegia, in the fourth decade of life. Hexosaminidase A activity, assayed using both synthetic and natural substrates, was severely reduced in the patients' plasma, leukocytes, and skin fibroblasts. Enzyme activity in their parents was in a similar range to that seen in heterozygotes for Tay-Sachs disease. The increasing evidence for marked clinical and molecular heterogeneity in the GM2 gangliosidoses warrants their consideration in the diagnosis of multisystem degenerative neurological disorders, even if onset of symptoms is in adult life. Images PMID:2956362

  11. 'Brothers in arms'

    DEFF Research Database (Denmark)

    Adamsen, L; Rasmussen, J M; Pedersen, L S

    2001-01-01

    The study investigated how a group intervention programme (13 sessions over 16 weeks), designed for men with cancer (n = 17), affected their sense of well-being and had a positive impact on their ability to cope with the physical, psychological and social consequences of living with cancer. The c...

  12. My Brother the Mexican

    Directory of Open Access Journals (Sweden)

    K. Angelique Dwyer

    2017-10-01

    Full Text Available El “Piti” le decían, I never knew why. We lived just outside “El Barrio,” at least that’s what they called it, ‘cause it took too long to say “Tlachichilco del Carmen.” Nobody called it that, but my mom. She would make us go to El Barrio a vender “panquecitos.” Two little gringüitos selling cupcakes en la plaza. ...

  13. Big Brother Not Needed.

    Science.gov (United States)

    Heinen, Edward

    1983-01-01

    Cites the recent United States State Department's labeling of recent Canadian films--one on nuclear war and two on acid rain--as political propaganda as a sign of the need to review the nature of propaganda. Suggests that teaching students to intelligently evaluate propaganda is preferable to submitting to government dictum. (MM)

  14. Band of Brothers

    DEFF Research Database (Denmark)

    Pærregaard, Karsten

    2011-01-01

    Kapitlet diskuterer den rolle, som katolske broderskaber spiller i peruanske migranters religiøse praksis i USA, Spanien og andre lande. Den introducerer kort de katolske broderskabers historie i Spanien og det kolonial Latin Amerika og undersøger derpå det spirituelle slægtskab, som forbinder pe...

  15. Mercury is Moon's brother

    International Nuclear Information System (INIS)

    Ksanfomalifi, L.V.

    1976-01-01

    The latest information on Mercury planet is presented obtained by studying the planet with the aid of radar and space vehicles. Rotation of Mercury about its axis has been discovered; within 2/3 of its year it executes a complete revolution about its axis. In images obtained by the ''Mariner-10'' Mercurys surface differs little from that of the Moon. The ''Mariner-10'' has also discovered the Mercurys atmosphere, which consists of extremely rarefied helium. The helium is continuously supplied to the planet by the solar wind. The Mercury's magnetic field has been discovered, whose strength is 35 x 10 -4 at the Equator and 70 x 10 -4 E at the poles. The inclination of the dipole axis to the Mercury's rotation axis is 7 deg

  16. Teste de lixiviação de potássio para avaliação do vigor de sementes de soja [Glycine max (L.Merril] Potassium leaching test for the evaluation of soybean seed vigour

    Directory of Open Access Journals (Sweden)

    D.C.F.S. Dias

    1995-12-01

    Full Text Available O presente trabalho teve como objetivo principal investigar a possibilidade de se obter indicações rápidas sobre a qualidade fisiológica de sementes de soja através do teste de lixiviação de potássio, cuja eficiência foi avaliada comparativamente as informações fornecidas por outros métodos considerados adequados para a determinação do vigor. Para tanto, utilizou-se quatro lotes de sementes de soja dos cultivares IAC-8 e IAC-15 que foram submetidos aos testes de germinação, primeira contagem de germinação, envelhecimento artificial, condutividade elétrica e determinação do grau de umidade. Além destes foram conduzidos estudos de lixiviação de potássio utilizando-se amostras de sementes não danificadas e de sementes fisicamente puras. A quantidade de potássio lixiviado foi avaliada em fotômetro de chama após 60, 90, 120 e 150 minutos de embebição a 30ºC. As avaliações feitas aos 60, 90 e 120 minutos mostraram-se adequadas para a identificação de lotes com diferentes níveis de vigor, constituindo-se em um método simples e rápido para a avaliação da qualidade fisiológica das sementes.This work was performed to investigate the possibilities of providing rapid indications on the physiological quality of seeds through the potassium leaching test. Four lots of soybean (Glycine max (L. Merrill seeds, cultivars IAC-8 and IAC-15 were submitted to germination, first count, accelerated aging, electrical conductivity and seed moisture tests. In addition, studies on potassium leaching were conducted with samples of selected non damaged seeds and with pure seeds. The amount of leached potassium was evaluated in a flame photometer after a 60, 90, 120 and 150 minute imbibition at 30°C. The evaluations after 60, 90 and 120 minutes were suitable for the identification of lots with different levels of vigour, thus proving to be a simple and rapid method for seed vigour evaluation.

  17. Surgical Treatment for Epstein-Barr Virus Otomastoiditis Complicated by Facial Nerve Paralysis: A Case Report of Two Young Brothers and Review of Literature.

    Science.gov (United States)

    Eeten, Evelien van; Faber, Hubert; Kunst, Dirk

    2017-04-01

    We report the case of two young brothers with Epstein-Barr virus (EBV) otomastoiditis complicated by a facial nerve paralysis. The boys, aged 7 months (patient A) and 2 years and 8 months (patient B), were diagnosed with a facial nerve paralysis House-Brackmann (HB) grade IV (A) and V (B). After unsuccessful pharmacological treatment, patient A underwent mastoidectomy and atticoantrotomy and patient B underwent a transmastoidal surgical decompression of the facial nerve. They recovered to HB grades I and II facial nerve palsy (FNP), respectively. Although rare and relatively unknown, EBV should be considered in the differential diagnosis of children with FNP of unknown cause. Surgical intervention may be a viable therapy with good recovery.

  18. Armuloo lõpp / Merril Stevenson

    Index Scriptorium Estoniae

    Stevenson, Merril

    2006-01-01

    Briti peaministri Tony Blairi ametist lahkumise järel arvatakse esile kerkivat kahte tugevamat liidrit, ühelt poolt konservatiivide peaministrikandidaat David Cameron, teisalt leiboristide Gordon Brown - järglane praegusele peaministrile. Vt. samas: Maailma liider otsib järgmist suurt väljakutset

  19. Terapia de linguagem de irmãos com transtornos invasivos do desenvolvimento: estudo longitudinal Language therapy of brothers with pervasive developmental disorders: longitudinal study

    Directory of Open Access Journals (Sweden)

    Andréa Regina Nunes Misquiatti

    2010-01-01

    Full Text Available O objetivo deste trabalho foi descrever o processo de intervenção fonoaudiológica de dois irmãos com transtornos invasivos do desenvolvimento, por meio de um estudo longitudinal de caso clínico. Participaram dois irmãos, um de nove e outro de 11 anos de idade, ambos do gênero masculino, com autismo (Caso 1 e transtorno invasivo do desenvolvimento sem outra especificação (Caso 2. Como procedimento de coleta e análise de dados foi realizado um estudo longitudinal, por meio de acompanhamento dos casos ao longo de quatro anos de intervenção fonoaudiológica. Foram realizadas filmagens durante as sessões de terapia, análise documental de informações dos prontuários referentes à anamnese, avaliação e relatórios terapêuticos fonoaudiológicos, exames e avaliações multidisciplinares. Em ambos os casos houve melhora no contato visual, na interação social, no vocabulário e na brincadeira simbólica. No Caso 1 ocorreu aumento de 2,0 para 6,2 atos comunicativos por minuto, no Caso 2 de 3,5 para 8,0 atos e ambos demonstraram predominância do meio verbal e maior variedade de funções comunicativas. Outros fatores influenciaram estes resultados, como a deficiência intelectual, a dinâmica familiar, os conflitos no relacionamento entre os irmãos e o ambiente escolar em que estavam inseridos. Confirmou-se a relevância do fonoaudiólogo em intervenções nos transtornos invasivos do desenvolvimento, junto a equipes multidisciplinares, para a discussão diagnóstica e de condutas mais adequadas. Estudos longitudinais podem contribuir para uma análise mais detalhada e fidedigna de intervenções terapêuticas nesses casos, para esclarecer lacunas existentes na literatura e subsidiar a atuação do fonoaudiólogo clínico.The aim of this research was to describe the language intervention process of two brothers with pervasive developmental disorders, through a longitudinal clinical case study. Two brothers - one nine and the other 11

  20. de accountant als ideale klokkenluider

    NARCIS (Netherlands)

    Paape, L.

    2011-01-01

    De golven van financiële schandalen lijken zich steeds sneller aan te dienen. Tussen de bankschandalen van de jaren tachtig en het Enron-debacle zat nog twintig jaar, tussen het laatste en de crash van Lehman Brothers nog maar vijf. De overheden reageren met golven nieuwe regelgeving om de risico’s

  1. Regime-dependent determinants of Euro area sovereign CDS spreads

    NARCIS (Netherlands)

    Blommestein, H.J.; Eijffinger, Sylvester; Qian, Zongxin

    We study the determinants of sovereign CDS spreads of five Euro area countries (Greece, Ireland, Italy, Portugal, and Spain) after the collapse of Lehman Brothers. We find that global and/or European Monetary Union (EMU)-wide factors are the main drivers of changes in the sovereign CDS spreads in

  2. Cenové skoky během finanční nejistoty: od intuice k regulační perspektivě

    Czech Academy of Sciences Publication Activity Database

    Hanousek, Jan; Novotný, J.

    2014-01-01

    Roč. 62, č. 1 (2014), s. 32-48 ISSN 0032-3233 R&D Projects: GA ČR(CZ) GA14-27047S Institutional support: RVO:67985998 Keywords : European emerging stock markets * Lehman Brothers * price jumps * financial crisis Subject RIV: AH - Economics Impact factor: 0.650, year: 2014

  3. FBI hakkab Wall Streeti puistama / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2008-01-01

    FBI hakkab uurima nelja äsja hiigelkahjumeid kandnud suurfirmat - Fannie Mae, Freddie Mac, Lehman Brothers, AIG - võimaliku hüpoteegipettuse pärast. Hüpoteegikriisi pärast on uurimise all ka ligi 1400 individuaalset kinnisvaravahendajat. USA-s levivast kinnisvarapetuskeemist. Lisa: Kongress vaidleb triljonite üle

  4. The paths of salvation and eternal condemnation: The presence of the allegory in the History of the Elected Pilgrim and his Brother Precito (1682, de Alexandre de Gusmão

    Directory of Open Access Journals (Sweden)

    José Adriano Filho

    2015-04-01

    Full Text Available The repercussions of the echoes of the Council of Trent (1546-1563, the Counter Reform movement, and the repercussions they had on the artistic production in the Catholic world. The pedagogical-didactic intents behind its composition are grounded on the belief that art could be an effective tool for reconverting of the faithful and for indoctrination in the values of the Catholic faith. Considering that, this paper aims at presenting the way allegory became an important tool for the interpretation and construction of religious discourse, as we can see in the History of the Elected Pilgrim and his Brother Precito. The book is an allegorical narrative that presents the history of two pilgrim brothers born in Egypt from where they set out with the intention of making a fortune (one brother goes to Jerusalem, and the  other one goes to Babylon. In this way, the book presents continuity with the medieval pattern that highlights the journey, especially the path for salvation. The readiness of allegory to transmit abstract concepts through concrete visualizations allied to a form of indirect expression made it a powerful, didactic, apologetic, and entertaining tool for that time.

  5. THE EVANGELICAL AS THE NATIVE IN THE “BROTHERS KARAMAZOV” AND IN “A WRITER’S DIARY” (1876–1877 BY FYODOR DOSTOEVSKY

    Directory of Open Access Journals (Sweden)

    Elena A. Fedorova

    2015-11-01

    Full Text Available The article identifi es the reasons for Fyodor Dostoevsky’s appeal to the traditions of Old Russian literature in “A Writer’s Diary” during the Russian-Turkish war. One of the main reasons is seeking for national foundations of Russian spirituality. The writer learned the world of medieval literacy getting acquainted with hagiography, walking, spiritual eloquence. Later Dostoevsky reverted to the Old Russian monuments in the course of his work on the novel “The Brothers Karamazov” (in particular on the chapter “Th e Russian Monk”. As follows from the comparison of the texts the dominant qualities of the ideal image of a Russian saint are repentance, humility and suff ering, desire for purifi cation, spiritual ability to resist the evil. The ideal form of existence of Russian people becomes conciliarism. The type of historicism is the movement to the Last Judgment. Gospel allusions and metaphors reinforce the author’s interpretation. Th us, Dostoevsky carries on the dialogue with the evangelical word at an ideological, imaginative, genre, motive and narrative level of the text. Th e hallmark of the works of Fyodor Dostoevsky who followed the evangelical tradition, becomes a dialogical word.

  6. A Significant Source for the Madeleine and Other Major Episodes in Combray: Proust's Intertextual Use of Pierre Loti's My Brother Yves

    Directory of Open Access Journals (Sweden)

    Richard M. Berrong

    2014-01-01

    Full Text Available The most famous passage in Marcel Proust’s In Search of Lost Time , and one of the most famous passages in Western literature, is the moment when the narrator sips tea while eating a shell-shaped pastry called a madeleine and suddenly recalls very vividly an apparently long-forgotten scene from his childhood. From this episode Proust developed his theories about involuntary memory and its important role in our emotional welfare. Proust was an avid reader of the French novelist Pierre Loti when he was young. Contemporary accounts show that he was able to recite whole passages from Loti’s work in public from memory. This article demonstrates the extent to which Proust made intertextual use of scenes from Loti’s novel My Brother Yves in constructing the madeleine and other famous passages in Combray , the first section of In Search of Lost Time. It does not attempt to question the originality of Proust’s work. Rather, building on previous studies of intertextuality in Proust, it seeks to show how the author went about creating his work and dialoguing with at least some of his potential contemporary readers.

  7. Characteristics of Cu isotopes from chalcopyrite-rich black smoker chimneys at Brothers volcano, Kermadec arc, and Niuatahi volcano, Lau basin

    Science.gov (United States)

    Berkenbosch, H. A.; de Ronde, C. E. J.; Paul, B. T.; Gemmell, J. B.

    2015-10-01

    We analysed primary chalcopyrite from modern seafloor `black smoker' chimneys to investigate high-temperature hydrothermal Cu isotope fractionation unaffected by metamorphism. Samples came from nine chimneys collected from Brothers volcano, Kermadec arc, and Niuatahi volcano, Lau backarc basin. This is the first known study of Cu isotopes from submarine intraoceanic arc/backarc volcanoes, with both volcanoes discharging significant amounts of magmatic volatiles. Our results ( n = 22) range from δ65Cu = -0.03 to 1.44 ± 0.18 ‰ (2 sd), with the majority of samples between ˜0.00 and 0.50 ‰. We interpret this cluster ( n = 17) of lower δ65Cu values as representing a mantle source for the chimney Cu, in agreement with δ65Cu values for mantle rocks. The few higher δ65Cu values (>0.90 ‰) occur (1) within the same chimneys as lower values, (2) randomly distributed within the chimneys (i.e. near the top and bottom, interior and exterior), and (3) within chalcopyrite of approximately the same age (responsible for the observed isotopic fractionation. When compared to global δ65Cu data for primary chalcopyrite, volcanic arc chimneys are most similar to porphyry copper deposits that also form from magmatic-hydrothermal processes in convergent tectonic settings.

  8. Brother of the regulator of the imprinted site (BORIS variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy.

    Directory of Open Access Journals (Sweden)

    Ryota Horibe

    Full Text Available Lung cancer is one of the most common malignancies with a high rate of mortality. Lung cancer stem-like cells (CSCs/ cancer-initiating cells (CICs play major role in resistance to treatments, recurrence and distant metastasis and eradication of CSCs/CICs is crucial to improve recent therapy. Cytotoxic T lymphocytes (CTLs are major effectors of cancer immunotherapy, and CTLs recognize antigenic peptides derived from antigens that are presented by major histocompatibility complex (MHC class I molecules. In this study, we analyzed the potency of a cancer-testis (CT antigen, brother of the regulator of the imprinted site variant subfamily 6 (BORIS sf6, in lung CSC/CIC immunotherapy. BORIS sf6 mRNA was expressed in lung carcinoma cells (9/19, especially in sphere-cultured lung cancer stem-like cells, and in primary lung carcinoma tissues (4/9 by RT-PCR. Immunohistochemical staining using BORIS sf6-specific antibody revealed that high expression of BORIS sf6 is related to poorer prognosis. CTLs could be induced by using a human leukocyte antigen, (HLA-A2 restricted antigenic peptide (BORIS C34_24(9, from all of 3 HLA-A2-positive individuals, and CTL clone cells specific for BORIS C34_24(9 peptide could recognize BORIS sf6-positive, HLA-A2-positive lung carcinoma cells. These results indicate that BORIS sf6 is a novel target of lung cancer immunotherapy that might be useful for targeting treatment-resistant lung cancer stem-like cells.

  9. Síndrome de Waardenburg: achados audiológicos em 2 irmãos Waardenburg's syndrome: audiological findings in 2 brothers

    Directory of Open Access Journals (Sweden)

    Carlos Henrique F. Martins

    2003-01-01

    Full Text Available A síndrome de Waardenburg foi inicialmente descrita em 1951 por P.J. Waardenburg, como uma condição autossômica dominante que apresenta penetrância e expressividade variáveis de seus caracteres. Os sinais clínicos mais frequentes são: deslocamento lateral dos cantos internos dos olhos (telecanto, hiperplasia da porção medial dos supercílios (sinofris, base nasal proeminente e alargada, alterações na pigmentação da íris e da pele, surdez congênita, mecha branca frontal ou encanecimento precoce. Este estudo foi realizado em dois irmãos de uma família, que apresentavam características clínicas da síndrome de Waardenburg, entre elas a deficiência auditiva. Os pacientes foram submetidos à uma avaliação otorrinolaringológica, audiológica e genética.Waardenburg's Syndrome, first described in 1951 by P.J. Waardenburg, is an autossomal dominant condition with variable penetrance and expressivity of its features. The clinical signs are lateral displacement of the inner canthi of the eyes, confluent eyebrows, broad and prominent nasal root, pigmentation changes of the irises and skin, sensorineural deafness, white forelock or early graying of the hair. This study was based on two brothers who presented a typical clinical picture of Waardenburg's Syndrome, including hearing loss. Otolaryngological, audiological and genetical evaluations were conducted.

  10. ['Charitable brothers' in charge of hospitals in early modern times: The hospital in Linz/Austria and its patients up to c. 1780].

    Science.gov (United States)

    Watzka, Carlos

    2008-01-01

    The article deals with the history of the Hospital of the Brothers of St. John of God (in German: "Barmherzige Brüder"; official name "Ordo Hospitalarius Sancti Joannis a Deo") in the capital of Upper Austria, Linz, from its founding in 1757 to c. 1780. Primarily, the organisational development and the patients of the institute are discussed. The order's hospital already functioned as a medical hospital for the treatment of acute diseases: It was oriented towards the reestablishment of health of its inmates during short time and offered treatment by a staff of learned medical experts, among them academically trained physicians. The accommodation of the patients yet took place in a largely undifferentiated manner, as most of them were situated in a large common hall. This was obviously a consequence of the comparatively little capacity of the organisation, too, which sustained about 12 beds in the beginning, and about 20 around 1780. Nonetheless, the number of patients treated there summed up to nearly 1% of the entire male population of Upper Austria even during the first decade of its existence. In early modern time, only men were admitted to this hospital, the average age of them being only ca. 30 years. As far as social status is concerned, most of them (according to a representative sample out of the admissions of 1757-1767) were handicraftsmen (more than two thirds), labourers and servants. Thus, the organisation was obviously destined to broad social strata, but by no way displays itself as a poorhouse. Average annual mortality was 10 to 13%, which is comparable to that of other hospitals of the order in 18th century Austria. Most of the admitted persons suffered from "fever" or inner diseases and were dismissed as healed already after some weeks of stay.

  11. All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.

    Science.gov (United States)

    Kavran, Jennifer M; Ward, Matthew D; Oladosu, Oyindamola O; Mulepati, Sabin; Leahy, Daniel J

    2010-08-06

    Hedgehog (Hh) signaling proteins stimulate cell proliferation, differentiation, and tissue patterning at multiple points in animal development. A single Hh homolog is present in Drosophila, but three Hh homologs, Sonic Hh, Indian Hh, and Desert Hh, are present in mammals. Distribution, movement, and reception of Hh signals are tightly regulated, and abnormal Hh signaling is associated with developmental defects and cancer. In addition to the integral membrane proteins Patched and Smoothened, members of the Drosophila Ihog family of adhesion-like molecules have recently been shown to bind Hh proteins with micromolar affinity and positively regulate Hh signaling. Cell adhesion molecule-related, down-regulated by oncogenes (CDO) and Brother of CDO (BOC) are the closest mammalian relatives of Drosophila Ihog, and CDO binds Sonic Hh with micromolar affinity and positively regulates Hh signaling. Despite these similarities, structural and biochemical studies have shown that Ihog and CDO utilize nonorthologous domains and completely different binding modes to interact with cognate Hh proteins. We report here biochemical and x-ray structural studies of Sonic, Indian, and Desert Hh proteins both alone and complexed with active domains of CDO and BOC. These results show that all mammalian Hh proteins bind CDO and BOC in the same manner. We also show that interactions between Hh proteins and CDO are weakened at low pH. Formation of Hh-mediated Hh oligomers is thought to be an important feature of normal Hh signaling, but no conserved self-interaction between Hh proteins is apparent from inspection of 14 independent Hh-containing crystal lattices.

  12. Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    DEFF Research Database (Denmark)

    Vorwerk, P; Christoffersen, C T; Müller, J

    1999-01-01

    to be compound heterozygotes for mutations in the IR gene. The maternal allele was alternatively spliced in exon 17 due to a point mutation in the -1 donor splice site of the exon. The abnormal skipping of exon 17 shifts the amino acid reading frame and leads to a truncated IR, missing the entire tyrosine kinase......The insulin receptor (IR) in two brothers with a rare syndrome of congenital muscle fiber type disproportion myopathy (CFTDM) associated with diabetes and severe insulin resistance was studied. By direct sequencing of Epstein-Barr virus-transformed lymphocytes both patients were found...

  13. Big Brother, little brother en de discussie over privacy

    NARCIS (Netherlands)

    Dr. Martijn de Groot

    2014-01-01

    In 1949 publiceerde George Orwell zijn boek ‘1984’, waarin hij een beklemmende samenleving beschrijft: een wereld die totaal gecontroleerd wordt door de overheid, waarbij élke stap die je doet wordt geregistreerd en zelfs het denken aan banden is gelegd. Nu, 65 jaar later, lijkt het niet Big

  14. Who is my brother's keeper?

    Science.gov (United States)

    Kottow, M H

    2002-02-01

    Clinical and research practices designed by developed countries are often implemented in host nations of the Third World. In recent years, a number of papers have presented a diversity of arguments to justify these practices which include the defence of research with placebos even though best proven treatments exist; the distribution of drugs unapproved in their country of origin; withholding of existing therapy in order to observe the natural course of infection and disease; redefinition of equipoise to a more bland version, and denial of post-trial benefits to research subjects. These practices have all been prohibited in developed, sponsoring countries, even though they invariably have pockets of poverty where conditions comparable to the Third World prevail. Furthermore, the latest update of the Declaration of Helsinki clearly decries double ethical standards in research protocols. Under these circumstances, it does not seem appropriate that First World scholars should propose and defend research and clinical practices with less stringent ethical standards than those mandatory in their own countries. Recent years have witnessed frequent reports of less stringent ethical standards being applied to both clinical and research medical practices, for the most part in the field of drug trials and drug marketing, initiated by developed countries in poorer nations. Still more unsettling, a number of articles have endorsed the policy of employing ethical norms in these host countries, which would be unacceptable to both the legislations and the moral standards of the sponsor nations. Also, these reformulations often contravene the Declaration of Helsinki or one of its updates. This paper is not so much concerned with the actual practices, which have been subjected to frequent scrutiny and publicly decried when gross misconduct occurred. Rather, my concern relates to the approval and support such practices have found in the literature on bioethics from authors who might be expected to use their energy and scholarship to explore and endorse the universalisability of ethics rather than to develop ad hoc arguments that would allow exceptions and variations from accepted moral standards. To this purpose, issue will be taken with arguments in three fields: medical and pharmaceutical practices, research strategies, and local application of research results.

  15. Gregorio y Francisco Esparza: hermanos enfrentados ante la independencia de Texas, 1835-1836 Gregorio and Francisco Esparza: Brothers Who Fought Each Other During the Independence of Texas, 1835-1836

    Directory of Open Access Journals (Sweden)

    Gustavo Ernesto Emmerich

    2012-08-01

    Full Text Available En 1836 el ejército mexicano tomó el fuerte de El Álamo, en las afueras de San Antonio. Todos sus defensores, que combatían por la independencia de Texas, murieron en la acción, entre ellos Gregorio Esparza, un nativo de esa ciudad. Tras la batalla, su hermano Francisco, enrolado en el bando mexicano, le dio cristiana sepultura. Este artículo examina la saga de ambos hermanos virtualmente desconocida en México. La primera sección de este artículo contextualiza la independencia de Texas, la segunda contiene resultados de investigación documental realizada por el autor sobre Gregorio y Francisco Esparza. La tercera comenta una entrevista realizada a un hijo de Gregorio sobre los papeles de su padre y su tío en El Álamo. La cuarta evalúa críticamente las evidencias. La quinta ofrece una reflexión sobre los motivos que habrían llevado a los hermanos Esparza -y en general a la comunidad texana de origen mexicano- a enfrentarse respecto a la independencia de Texas y, finalmente, en los anexos se transcriben los registros parroquiales y censales de la época y se extractan y comentan diversos relatos del hijo de Gregorio y de otros descendientes.In 1836, the Mexican army captured Fort Alamo outside San Antonio. All its defenders, who were fighting for the independence of Texas, died in action. Among these was Gregorio Esparza, a native of that city. After this battle, his brother Francisco, enlisted in the Mexican army, gave him a Christian burial. This article examines the saga of the two brothers, virtually unknown in Mexico. The first section contextualizes the independence of Texas. The second contains the results of the author's documentary research on Gregorio and Francisco Esparza. The third comments on an interview with one of Gregorio's sons on the roles played by his father and uncle at The Alamo. The fourth critically evaluates the evidence. The fifth provides a reflection on the reasons that led the Esparza brothers -and the

  16. Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    DEFF Research Database (Denmark)

    Vorwerk, P; Christoffersen, C T; Müller, J

    1999-01-01

    to be compound heterozygotes for mutations in the IR gene. The maternal allele was alternatively spliced in exon 17 due to a point mutation in the -1 donor splice site of the exon. The abnormal skipping of exon 17 shifts the amino acid reading frame and leads to a truncated IR, missing the entire tyrosine kinase......The insulin receptor (IR) in two brothers with a rare syndrome of congenital muscle fiber type disproportion myopathy (CFTDM) associated with diabetes and severe insulin resistance was studied. By direct sequencing of Epstein-Barr virus-transformed lymphocytes both patients were found...... domain. In the correct spliced variant, the point mutation is silent and results in a normally translated IR. The paternal allele carries a missense mutation in the tyrosine kinase domain. All three cDNA variants were present in the lymphocytes of the patients. Purified IR from 293 cells overexpressing...

  17. Financial Contagion in the Recent Financial Crisis: Evidence from the Romanian Capital Market

    Directory of Open Access Journals (Sweden)

    Cărăușu Dumitru-Nicușor

    2017-01-01

    Full Text Available We use the wavelet analysis in order to investigate if financial contagion occurred between the US and the Romanian capital market in the beginning of the recent economic crisis. Moreover, we test presence of pure and fundamental contagion between the two markets using wavelet coherency analysis and maximal overlap discrete wavelet transform methodology. We find evidence of pure financial contagion between the two markets: during the sub-primes crisis period, the Lehman Brothers collapse and at the beginning of sovereign debt crisis. Furthermore, we find a general short-term increase in interdependence between the two markets in the ex-ante and ex-post Lehman brothers period. Meanwhile, the capital market from Romania and US were in perfect sync during 2007-2009 for high trading time-windows. This implies that the Romanian market was sensitive to short-term shock from the US market, which lead to a long-term fundamental contagion.

  18. The Financial Crisis and White Collar Crime - Legislative and Policy Responses

    OpenAIRE

    Ryder, N.; Turksen, U.; Tucker, J.

    2017-01-01

    In September 2007, the collapse of the United States (US) sub-prime mortgage market resulted in the global meltdown of the financial markets. This in turn led to the collapse of many international financial institutions including Northern Rock, Bradford and Bingley, American Insurance Group, Freddy Mac, Fannie Mae and Lehman Brothers. The G20 countries responded with a plethora of financial stimulus packages aimed at combating the largest global financial problem since the Wall Street Crash i...

  19. Cenové skoky během finanční nejistoty: od intuice k regulační perspektivě

    Czech Academy of Sciences Publication Activity Database

    Hanousek, J.; Novotný, Jan

    2014-01-01

    Roč. 62, č. 1 (2014), s. 32-48 ISSN 0032-3233 R&D Projects: GA ČR(CZ) GBP402/12/G097 Grant - others:UK(CZ) UNCE 204005/2012 Institutional support: PRVOUK-P23 Keywords : European emerging stock markets * Lehman Brothers * price jumps * financial crisis Subject RIV: AH - Economics Impact factor: 0.650, year: 2014

  20. Employing Land-Based Anti-Ship Missiles in the Western Pacific

    Science.gov (United States)

    2013-01-01

    includes such obstacles as drilling platforms, a volcano , and small islands that make its transit very challenging. 24 Lehman Brothers, Global Oil...Platform MM-38 Exocet France 40 INS, active radar Cameroon, Chile , Colombia, Cyprus, Ecuador, Germany, Greece, Indonesia, Iraq, Ivory Coast, South Korea...INS, active radar Belgium, Brazil, Brunei, Cameroon, Chile , Colombia, Cyprus, Ecuador, Germany, Greece, Indonesia, Iraq, Ivory Coast, South Korea

  1. اثر استراتيجية ليمان ( فكر – زاوج – شارك في تحصيل تلميذات الصف الخامس الابتدائي ومستوى طموحهن في مادة العلوم العامة The effect of a strategy for Lehman (Think - Pair - participated in the collection of schoolgirls fifth grade and the level of ambitions in science general

    Directory of Open Access Journals (Sweden)

    Nisreen Hamza Al-sulani م.م نسرين حمزة السلطاني

    2015-01-01

    Full Text Available The research aims to study the effect of a strategy for Lehman (Think - Pair - participated in the collection of schoolgirls fifth grade and the level of ambitions in science general , study sample consisted of pupils School Aleem fifth grade primary school for the academic year 2013-2014 and reached their number ( 80 schoolgirl . The results of research on the following : The presence of statistically significant differences at the level ( 0.05 between the average score for the collection of students who are studying using a strategy (Think - Pair - co , and the average score for the collection of students who are studying in the usual way in science public . - The presence of statistically significant differences at the level ( 0.05 between the average scores measure the level of ambition for the pupils of the experimental group who were studying strategy (Think - Pair - co and the control group who were studying in the usual way . In light of this, the researcher concluded to a number of conclusions and recommendations and proposals .

  2. Cluster fusion-fission dynamics in the Singapore stock exchange

    Science.gov (United States)

    Teh, Boon Kin; Cheong, Siew Ann

    2015-10-01

    In this paper, we investigate how the cross-correlations between stocks in the Singapore stock exchange (SGX) evolve over 2008 and 2009 within overlapping one-month time windows. In particular, we examine how these cross-correlations change before, during, and after the Sep-Oct 2008 Lehman Brothers Crisis. To do this, we extend the complete-linkage hierarchical clustering algorithm, to obtain robust clusters of stocks with stronger intracluster correlations, and weaker intercluster correlations. After we identify the robust clusters in all time windows, we visualize how these change in the form of a fusion-fission diagram. Such a diagram depicts graphically how the cluster sizes evolve, the exchange of stocks between clusters, as well as how strongly the clusters mix. From the fusion-fission diagram, we see a giant cluster growing and disintegrating in the SGX, up till the Lehman Brothers Crisis in September 2008 and the market crashes of October 2008. After the Lehman Brothers Crisis, clusters in the SGX remain small for few months before giant clusters emerge once again. In the aftermath of the crisis, we also find strong mixing of component stocks between clusters. As a result, the correlation between initially strongly-correlated pairs of stocks decay exponentially with average life time of about a month. These observations impact strongly how portfolios and trading strategies should be formulated.

  3. Duas variantes da representação do real na cultura midiática: o exorbitante Big Brother brasil e o circunspeto Edifício Master

    Directory of Open Access Journals (Sweden)

    Fernando Andacht

    2005-06-01

    Full Text Available The text aims at describing a remarkable phenomenon in our present day media culture: the representation of the real in television and cinema. Through the comparison between two audiovisual genres which deal with the real in the media, the Edificio Master documentary, directed by Eduardo Coutinho, and the Big Brother Brasil television program, the aim is to understand the cultural signification of two very different esthetic products that, nevertheless, share the dominant use of indexical signs, as their specific strategy. Without trying to minimize the obvious esthetic and ethic differences that exist between the reality show of the multinational company Endemol and the highly acclaimed Brazilian film, the article considers a fundamental tendency in present day media culture, namely, the techological and artistic production of an illusory intimacy at a distance, as a way of reflecting on identity. The functioning of the reality show aims at wrenching out of its orbit the normality of its participants, who must dwell in an abnormal place; the documentary, on the other hand, aims at offering a circumspect and moral vision of our everyday world, there where life takes place.

  4. Roasted soybeans (glycine max. (l) merril) for lactating dairy cows

    OpenAIRE

    Nelcy Madruga de Carvalho

    2001-01-01

    Soybeans were roasted in an experimental roaster during 2 or 3 minutes either at 380 or 490 ºC air temperature and kept or not for 30 minutes under steeping. The heat treatment effects on soybeans were evaluated in a first trial through two different procedures: a) after 16 hours of an “in situ” ruminal incubation period, all heat treated soybeans showed an increased (P0,05). In a second trial, soybeans roasted at 380 ºC, during 2 minutes and kept under steeping were included in isonitrogenou...

  5. Screening Soybean ( Glycine max (L) Merril) lines for morphological ...

    African Journals Online (AJOL)

    A study was carried out during the first and second seasonsofl997 at Namnlonge Agricultural and Animal Production Research Institute {NAAR I) to determine whether there were some soybean varieties in the NAARI germplasm which were resistant to the southern green stink bug, Nezara viridula and to establish the basis ...

  6. Radiation induced mutagenesis in soybean (Glycine Max L. Merrill)

    International Nuclear Information System (INIS)

    Wakode, M.M.; Nandanwar, R.S.; Patil, G.P.

    2000-01-01

    The mutagenic effects of gamma rays (10, 20 and 30 kR) on some biological parameter in M1 generation and frequency and spectrum of chlorophyll and morphological mutations in five cultivars of soybean viz. JS-8021, JS-335, JS- 7105, Monetta and PKV -1 have been studied. A dose dependant decrease was noticed in most of the characters like root length, shoot length, germination, plant height, plant survival and pollen sterility. While seedling height, number of seeds per pod and number of branches per plant were not affected significantly. The highest frequency and spectrum of chlorophyll and morphological mutations was noticed in variety JS-8021 in which 20 different gene loci for various characters were mutated. However variety JS- 7105 showed less radio sensitive response for different traits in which only 12 different loci were mutated. While JS-335, monetta and PKV-I showed moderate response to frequency and spectrum of various mutations. These varieties showed differential response to radio sensitivity, some useful mutations included, high yielding mutant in 20 kR, non shattering mutant in 30 kR and vine type mutant in 10 kR in variety monetta. Extra early type, erect and high branched type mutant were recorded with high frequency in 10 and 20 kR respectively in variety JS-8021. In general, 20 kR dose was found more effective in all the varieties studied. (author)

  7. Reaction of some selected soybean varieties ( Glycine max (L) Merril)

    African Journals Online (AJOL)

    In nematode endemic ecological zones, TGX-1985 – 8F is therefore recommended as it proved to contain some specialized genes that conferred a higher level of tolerance against root- knot nematode, Meloidogyne incognita. Key Words: Glycine max, root – knot nematode, Dominant loci, Mi – 1.2, leucine zipper and R ...

  8. Conservation and restoration of the panel "Saint Sebastian calling on the faith of the Christian captive brothers Marcus and Marcellianus" from the Museum of Angra do Heroísmo, Terceira Island, Azores

    Directory of Open Access Journals (Sweden)

    Raúl Gregório

    2010-01-01

    Full Text Available This paper describes the methodology followed in the conservation and restoration of the panel "Saint Sebastian calling on the faith of the Christian captive brothers Marcus and Marcellianus", datable to the late sixteenth century, belonging to the ancient altarpiece in the presbytery of the Church São Sebastião (Saint Sebastian, Terceira Island, Azores, and currently at the Museum of Angra do Heroísmo. It begins by presenting an historical overview and an iconographic and artistic study of the panel, which proved crucial to the understanding of the subject and its setting at the time, the church and the whole altarpiece. The double meaning as a testimony of faith and a symbol of national identity in times close to or already in the process of loss of independence from Portugal, is achieved through the hagiographic representation of the patron saint of the church on a base of cedar wood (Juniperus brevifolia, which enables to infer an author or local production. In the late nineties of the twentieth century, this support showed an intense deterioration resulting from colonization by fungi (brown rot and previous interventions. The work done back than was held by various thinning of the wood and partial filling that allowed the restoration of the physical balance of each one of five boards and the panel as a whole. After this phase, the intervention was stopped, coming to resume in 2007, with the further stabilization of wood, reassembly, repainting survey and treatment of pictorial layer. The methodology was adapted to the most current criteria, keeping only what had once been widely followed in the areas affected by fungal action, with a clear structural instability and inability to recover only by consolidating.

  9. Novel about Artist: Postmodern Variations (Instantiated by Novels “The Tin Drum” by Günter Grass, “Brother of Sleep” by Robert Schneider, “Perfume: The Story of a Murderer” by Patrick Süskind

    Directory of Open Access Journals (Sweden)

    Sofiya Varetska

    2013-12-01

    Full Text Available An attempt to show the modification of classic novel about an artist (Künstlerroman through a prism of postmodernism instantiated by German novels of the second half of the twentieth century “The Tin Drum”, “Brother of Sleep”, “Perfume: The Story of a Murderer” was accomplished. Crisis of artistic apperception in the twentieth century is demonstrated. Different conceptions of the creative process of main characters are compared. The main attention was focused on the clash between man and artist, life and art, daily routine and spirituality. In the postmodern age the cynical worldview model is predominating. At the same time tales, where magic and reality, sentimentality and brutality are combined, enjoy widespread popularity. An art of genius has positive connotations in general, but some of chosen novels are revealing the reverse side of the coin, when the art is capable to create an evil in its superior manifestations. For a wonder a presence of negative, monstrosity and disgust attract attention of the crowd rather than beauty. Therefore tin the article new idea that talent is on the verge of monstrosity is asserted. These two concepts exist together rely on each other. Every hero is like two-faced Janus to some extent. On the one hand, being endowed with Divine Grace he has a talent, but on the other hand, having something demoniacal is possessed by physical defect. On the one hand, they limelight and fire our imagination by their unusualness, on the other hand, they push away by their monstrosity and disgust. Main characters are always teetering on the edge. However the notion of edge is taking the wider meaning in the contemporary society. Consequently, having used all features of classic novel about an artist and portrayed them through a prism of modern perception of the world, writers created a new compilation – postmodern novel about an artist.

  10. 77 FR 75503 - Wright Brothers Day, 2012

    Science.gov (United States)

    2012-12-20

    .... Similar stories of resilient, canny entrepreneurship have unfolded throughout our Nation's history--from the founding of our airlines and auto industry to the growth of our research institutions and small businesses. While each journey has been unique, all have advanced that same brand of rugged determination to...

  11. 76 FR 79019 - Wright Brothers Day, 2011

    Science.gov (United States)

    2011-12-20

    ... collective memory. During the 12 seconds their aircraft remained aloft in Kitty Hawk's gusty headwinds... they overcame were tremendous, and Orville and Wilbur Wright's pioneering vision stands as a testament...

  12. HALF-BROTHERS IN THE SCHULHOF FAMILY?

    International Nuclear Information System (INIS)

    Vokrouhlicky, David; Nesvorny, David

    2011-01-01

    Disruptive collisions in the asteroid belt produced groups of fragments known as the asteroid families. The studies of identified asteroid families help us to better understand issues related to impact physics, space weathering, asteroid interior, and collisional evolution of the main belt. Here, we analyze a family near the central main belt asteroid (2384) Schulhof. We show that the previously found group of objects around (81337) 2000 GP36 is actually a sub-cluster in the larger Schulhof family. Using backward integrations we demonstrate that the orbits of sub-cluster asteroids converge to that of (2384) Schulhof at 780 ± 100 kyr ago, suggesting that the breakup event happened very recently. Interestingly, a similar analysis of the two newly discovered members of the Schulhof family may indicate a second event ∼< 100 kyr ago (e.g., secondary collision, fission, satellite instability). If confirmed, the formation history of the Schulhof family would suggest that small asteroids may have very colorful lifetimes. Additional astrometric observations of the two new member asteroids will be needed to improve their present orbit and better constrain their past histories.

  13. Unequal brothers : are homeopathy and hormesis linked?

    Science.gov (United States)

    Oberbaum, Menachem; Frass, Michael; Gropp, Cornelius

    2015-04-01

    The debate between those who believe homeopathy and hormesis derive from the same root and those who believe the two are different phenomena is as old as hormesis. It is an emotionally loaded discussion, with both sides fielding arguments which are far from scientific. Careful analysis of the basic paradigms of the two systems questions the claim of the homeopaths, who find similarities between them. The authors discuss these paradigms, indicating the differences between the claims of homeopathy and hormesis. It is time for thorough and serious research to lay this question to rest. One possible approach is to compare the activity of a hormetic agent, prepared in the usual way, with that of the same agent in the same concentration prepared homeopathically by serial dilution and succussion. Copyright © 2015. Published by Elsevier Ltd.

  14. 75 FR 80669 - Wright Brothers Day, 2010

    Science.gov (United States)

    2010-12-22

    ..., 1903, after years of determination and creativity, Orville and Wilbur Wright's wooden aircraft sailed... leadership and innovation has been the product of learning and ingenuity. To maintain this tradition and... children to become the entrepreneurs whose tenacity and creativity will power the engine of our Nation's...

  15. The 16th International Twin Congress: Highlights from Madrid/Twin Research: Twin Study of Partner Aggression; ABO Incompatibility in Dizygotic Twins; Growth Discordance in a Monoamniotic Twin Pair; Quick Note on Twin Implantation/In the Media: Long-Lost Twins Found; NASA Twin Experiment; Twin Brothers and the Las Vegas Attack; Retired Twin Airline Pilots; Twin Film Clips.

    Science.gov (United States)

    Segal, Nancy L

    2018-02-01

    Highlights from the 16th International Twin Congress, held in Madrid, Spain from November 16-18, 2017, are presented. The Twin Congress, formerly held every three years, now takes place biennially with a single-day meeting organized during the off years. This meeting is the largest gathering of scientific twin researchers, medical personnel, and representatives of multiple birth organizations in the world. This overview is followed by reviews of recent twin research and commentary concerning partner aggression, ABO incompatibility in dizygotic twins, growth discordance in a monoamniotic twin pair and twin implantation. The article closes with summaries of timely topics in the media, namely a father's finding of his long-lost twin children, early results from the NASA twin experiment, twin brothers at the center of the October 2017 Las Vegas attack, retired twin airline pilots, and clips from recent films with twin-based themes.

  16. An Approach toward an Asia-Pacific Strategy 2012 to 2020

    Science.gov (United States)

    2014-06-01

    of Chaos,” Foreign Affairs 89, no. 2 (March/April 2010): 18–32. 23. J. R. Wu and Jason Dean, “Wen Engages Web Users in Rare Web Chat,” Wall Street...Points (New York: Lehman Brothers, 18 January 2008), http://www .deepgreencrystals.com/images/GlobalOilChokePoints.pdf. 8. Jason Szep, “Burma Gas Pipeline...has rejoined the Coast Guard’s fleet, complementing the medium icebreaker Healey , thus changing this equation. 18. A United Press International (UPI

  17. Credit Default Swaps (CDS) y Collateral Debt Obligation (CDO) derivados financieros responsables de la crisis sub-prime de 2008 en Estados Unidos y una guía para el desarrollo del mercado de derivados exóticos en Colombia

    OpenAIRE

    Parra Abisambra, Maria Alejandra; Guevara Téllez, Christian Danilo

    2014-01-01

    La crisis financiera hipotecaria de 2008 en la que se declaró en quiebra el banco de inversión Lehman Brothers, se desarrolló en un ambiente que contemplaba apalancamientos financieros excesivos y el uso de derivados financieros de crédito innovadores. Razón por la cual, a partir del estudio de caso de quiebra de este banco de inversión y el análisis de las causas y consecuencias del ambiente desregulatorio que surgió en Estados Unidos desde la década de los 30 hasta el 2000, se orienta la i...

  18. La gestion du risque crédit par la méthode du scoring: cas de la Banque Populaire de Rabat-Kénitra

    OpenAIRE

    Elhamma, Azzouz

    2009-01-01

    National audience; La crise financière qui secoue le monde actuellement, notamment les défaillances successives des grandes banques internationales (Lehman Brothers aux Etats-Unis par exemple) ont remis sur le devant de la scène la problématique des risques bancaires dont le risque crédit. Ce risque doit être géré actuellement par des méthodes plus sophistiquées. Parmi ces méthodes, nous citons la méthode du scoring qui reste malheureusement inconnue dans notre pays. Cet article met évidence,...

  19. El rescate de Grecia y su comparación con España y otros países de la Unión Europea

    OpenAIRE

    Bernal Coronil, Rocío

    2016-01-01

    Las consecuencias de la crisis subprime en Estados Unidos así como la caída del Banco Lehman Brothers han provocado devastadoras consecuencias para Europa. Los países más débiles de la Unión Europea, sobre todo los de la periferia, vieron como su economía se iba debilitando como consecuencia de la crisis. La estructura de la Eurozona así como sus distintas soluciones para solventar la situación fueron tardías e ineficaces. Algunos países rescatados como Irlanda, Portugal, ...

  20. Negocio de restauración: dando la lata

    OpenAIRE

    Postigo Saura, Enrique

    2012-01-01

    Han pasado ya cinco años desde que comenzara el desplome de la economía mundial, con el consiguiente contagio a la economía española. Cronológicamente, todo empezó en julio de 2.007 con el resquebrajamiento del mercado inmobiliario norteamericano y el anuncio por parte del presidente de la reserva federal del riesgo de las llamadas " hipotecas basura". A finales del año 2.008, se produce la quiebra de Lehman Brothers y se descubre la estafa piramidal de Bernard Madoff. En el...

  1. The Recovery Framework in the BRRD and its Effectiveness, NORDIC & EUROPEAN COMPANY LAW Working Paper Series No. 15‐04

    DEFF Research Database (Denmark)

    Hu, Chenchen

    2015-01-01

    The EU has made great endeavors in establishing a bank resolution procedure after the global financial crisis (GFC). In April 2014 the directive on establishing a framework for the recovery and resolution of credit institutions and investment firms (referred to as The Bank Recovery and Resolution......-resolution recovery framework, including the intra-group support, recovery and resolution planning, and the early intervention in the wake of bank failures, such as Lehman Brothers fall. It aims at assessing to which extent the new recovery framework enhances the resilience of banks and facilitates orderly resolution...... procedure of failing banks....

  2. Bank ownership, lending, and local economic performance during the 2008–2009 financial crisis

    Science.gov (United States)

    Coleman, Nicholas; Feler, Leo

    2017-01-01

    Although government banks are frequently associated with political capture and resource misallocation, they may be well-positioned during times of crisis to provide countercyclical support. Following the collapse of Lehman Brothers in September 2008, Brazil’s government banks substantially increased lending. Localities in Brazil with a high share of government banks received more loans and experienced better employment outcomes relative to localities with a low share of government banks. While increased government bank lending mitigated an economic downturn, we find that this lending was politically targeted, inefficiently allocated, and reduced productivity growth. PMID:28936027

  3. Killing Brothers Legislation And Their Impact On The System Of Governance AL- Othman (1520-1617 شريعة قتل الأخوان وأثرها في نظام الحكم آل عثمان (1520-1617

    Directory of Open Access Journals (Sweden)

    Dr. Bushraa Nasser Hashim Alsaaedy م. د. بشرى ناصر هاشم الساعدي

    2011-12-01

    Full Text Available Ottoman state Faced throughout her reign, which lasted six centuries (1299-1922, many problems, had a clear impact in the ruling system. It was is in its infancy consolidate its power, and install its influence, to face external dangers surrounding its fledgling state entity. However, she found herself in the midst of serious internal problems was with temptation, and the competition between the sons and brothers of the sultans in anticipation of the throne of the Sultanate, and that was a cause for times the sultans influence in the inside, keeping their distance from their supreme goal of expansion and annexation outside the boundaries of the Sultanate. Has been a lot of brothers and sons of the sultans to murder or exclusion in the palaces of slaves, so unique new sultan ruling. But that it increased risk, with increased rivalry and conflict around the throne of the Sultanate, which led some of them to enter into agreements with their enemies in the neighboring United Arab Emirates them, or with foreign nations surrounding them, in order to obtain support and assistance to overthrow each other. If this case the Sultanate at home, which will become a contender for the throne ... To what extent was a reflection of that conflict in the ruling system. This is what we will try to follow in the folds of our humble research.

  4. Zanamivir (Glaxo Wellcome).

    Science.gov (United States)

    Oxford, J S

    2000-04-01

    of consumer problems with the product, following launch of the product in time for the 1999-2000 flu season [352392,335048]. In September 1998, Glaxo applied to the Canadian Health Protection Branch (HPB) for approval to market zanamivir for the treatment and prevention of influenza. A separate application for Fast Track approval was also made with the HPB [299375,299472]. In November 1999, zanamivir received approval in Canada [346474]. Glaxo expects to make MAA and NDA filings for the use of zanamivir as a prophylactic in 1999 [333494]. In July 1998, Merrill Lynch predicted that as zanamivir offered only modest benefits gained from a narrow treatment window, potential would be limited and forecast annual sales of US dollar 30 million [302048]. In January 1999, Paribas predicted sales of pounds 75 million in 1999, rising to pounds 280 million in 2003 [317650]. In April 1999, ABN Amro predicted sales of pounds 23 million in 1999, rising to pounds 326 million in 2003 [328676]. In August 1999, Lehman Brothers estimated that sales of zanamivir will reach US dollar 400 million by 2003, and that it is an obvious candidate for an OTC switch, although this is not likely until 5 years after launch [336356].

  5. Resposta da soja (Glycine max (L. Merrill à ação de bioestimulante = Soybean (Glycine max (L. Merrill response to biostimulant action

    Directory of Open Access Journals (Sweden)

    Celestina Alflen Klahold

    2006-04-01

    Full Text Available Objetivando verificar o efeito do bioestimulante, Stimulate®, aplicado via semente e pulverização foliar, na cultura da soja, conduziu-se um experimento sob ambiente protegido, em vasos. O delineamento foi de blocos casualizados, com 4 repetições. Os tratamentos constaram da combinação de doses de bioestimulate, aplicadas via semente (0, 3 e 5 mL kg-1 de sementes na semeadura e via foliar (0,0; 0,075; 0,150 e 0,225 mL L-1, aos 58 dias após a emergência (DAE. Realizaram-se coletas de plantas aos 73 e 129 DAE.Para algumas das variáveis estudadas, nas doses utilizadas, houve efeito negativo na resposta à aplicação de bioestimulante, para algumas doses testadas. Respostas positivas foram verificadas para massa seca de flores, raízes, razão raiz/parte aérea, número de flores, vagens e grãos e produção por planta. Destacaram-se positivamente os tratamentos: 0,0 mL 0,5 kg-1 (AS + 0,150 mL L-1 (APF; 3,0 mL 0,5 kg-1 (AS + 0,0 mL L-1 (APF; 3,0 mL 0,5 kg-1 (AS+ 0,225 mL L-1 (APF e 5,0 mL 0,5 kg-1 (AS + 0,075 mL L-1 (APF.Aiming to verify the effect of the bioestimulant, Stimulate®, applied saw by seed and leaf pulverization, in the culture of the soybean. It behaved an experiment under greenhouse, in vases. Randomized block experimental design was used, with four repetitions. The treatments consisted of the combination of bioestimulant doses: seed application (SA (0; 3; and 5 mL kg-1 of seeds in the sowing and leaf spray (LS (0.0; 0.075; 0.150; and 0.225 mL L- 1, to the 58 days after the emergency (DAE. Collections of plants were accomplished to the 73 and 129 DAE. For some of the studied variables, in the used doses, there was negative effect in the response of the biostimulant application, for some tested doses. Positives responses were verified for flowers and roots dry mass; root/shoot relation; flowers; beans and grains number; and yield for plant. They stood out the treatments: 0,0 mL 0.5 kg-1 (SA + 0.150 mL L-1 (LS; 3.0 mL 0.5 kg-1 (SA + 0.0 mL L-1 (LS; 3.0 mL 0.5 kg-1 (SA + 0.225 mL L-1 (LS; and 5.0 mL 0.5 kg-1 (SA + 0.075 mL L-1 (LS.

  6. LA CRISIS FINANCIERA: ¿ESTAFA, MALA GESTIÓN EMPRESARIAL, MAL MANEJO MACROECONÓMICO O UNA FALTA DE REGULACIONES? DE NUEVO LAS ENSEÑANZAS

    Directory of Open Access Journals (Sweden)

    Julio César Espinosa Rodríguez

    2012-05-01

    Full Text Available Resumen La intensificación de la crisis a nivel global, luego de la bancarrota de Lehman Brothers en septiembre del 2008, ha provocado que el actual entorno económico y financiero sea complicado para la economía mundial, el sector financiero a nivel global y para los bancos centrales. La actual crisis deriva de muchas causas; no obstante las principales son tres: primero, aspectos macroeconómicos; segundo, la inadecuada regulación de los entes encargados, y tercero, los reguladores estimularon el rápido crecimiento de los derivados en el mercado OTC. Abstract The amplification of the global financial crisis, following the bankruptcy of Lehman Brothers in September 2008, has made the present economic and financial environment a not easy time for the world economy, the global financial system and for central banks. There are many causes from the recent financial crisis. Main could be three. First, there were macroeconomic components. Second, the inadequate oversight/regulation provided by financial market regulators. And third, federal regulators have actively encouraged the rapid growth of over-the-counter (OTC derivatives and securities by all types of financial institutions.

  7. Technical Training Seminar: Physicists in the world of finance

    CERN Multimedia

    Davide Vitè

    2006-01-01

    Monday 27 February TECHNICAL TRAINING SEMINAR from 14:00 to 16:00, Council Chamber (bldg. 503) Physicists in the world of finance Oliver Cooke, Zhengyun Hu / LEHMAN BROTHERS (UK) Two PhD physicists will talk about their experiences of working in investment banking, describing what investment banks do and the jobs which attract physicists and engineers. They will introduce the derivatives markets, and explain the need for advanced modelling. In particular, they will present the many modelling techniques used, including Monte Carlo simulation, solving PDEs, stochastic calculus and data analysis. They will describe a typical day for a physicist in the world of finance, and present a case study in which they will show how they used an idea from physics to solve a finance problem. After a PhD and CERN fellowship on OPAL in the 1990s, Oliver Cooke moved to finance. He was initially a mathematical modeller of derivatives, and now is an exotic derivatives trader at Lehman Brothers in London. He will be j...

  8. Il Lago di Celluloide: immagini e pratiche di una meta turistica d'élite nelle rappresentazioni cinematografiche dai fratelli Lumière a Geogrge Clooney / The “Celluloid Lake”: images and practices of an elitist tourism destination in film productions from Lumière Brothers to George Clooney

    Directory of Open Access Journals (Sweden)

    Giuseppe Muti

    2016-05-01

    Full Text Available Il lago di Como è un caso di studio paradigmatico per l'unicità della dotazione ambientale e culturale, per la storia turistica lunga oltre duecento anni, per la forza dell'immagine che comprende alcune icone globali. Letterarie, poetiche, narrative, pittoriche, figurative, le immagini ricreative del lago di Como si modificano e si moltiplicano dall'età classica a quella romantica, presentandosi già definite e consolidate agli albori delle tecnologie fotografiche e cinematografiche. Il lago di celluloide nasce nel 1897 quando i fratelli Lumière riprendono una competizione fra imbarcazioni a Bellagio. Da allora il lago assume differenti connotazioni e ruoli come set di un gran numero di opere cinematografiche, la cui analisi diacronica permette interessanti riflessioni sulla natura delle relazioni fra turismo e audiovisivo, sulle diverse percezioni e rappresentazioni culturali di una medesimo territorio e sulle prerogative iconografiche specifiche di alcuni luoghi centrali della globalizzazione mediatica, cinematografica e turistica.   The Como Lake case study is paradigmatic for the unique environmental and cultural features, for the two-hundred-years-long touristic tradition and for the strength of its image, involving global icons. The recreational pictures of Como Lake are literary, poetic, narrative and pictorial. They have been constantly changing and multiplying beginning from the Classic to the Romantic Age, and became well-defined and strengthened before the dawn of photographic and cinematographic technologies. The "celluloid lake" debuts in 1897, when Lumière Brothers shoot a boat race in Bellagio. Since then, the lake took different connotations and roles as location for a large number of cinematographic productions, whose diachronic analysis leads to interesting thoughts on nature and the relationship between tourism and audiovisual footage, on different cultural perceptions and representations of the same territory and on the

  9. When “soul” is lost in translation: Metaphorical conceptions of “soul” in Dostoyevsky's original “Братья Карамазовы” (“The Brothers Karamazov” and its translations into Polish, Croatian and English

    Directory of Open Access Journals (Sweden)

    Julia Ostanina-Olszewska

    2017-12-01

    Full Text Available When soul is lost in translation: Metaphorical conceptions of soul in Dostoyevsky’s original Братья Карамазовы (The Brothers Karamazov and its translations into Polish, Croatian and English Given that our understanding of such an abstract concept as soul is almost purely metaphorical, this paper provides a comparative cross-linguistic analysis of the system of metaphorical conceptions of soul in Dostoyevsky’s original Братья Карамазовы (The Brothers Karamazov and its Polish, Croatian and English translations. Special attention is paid to those metaphors that are translated differently between the various translations, either in conceptual or linguistic terms. This paper adheres to the cognitive-linguistic approach to Mind (Reddy, 1979; Sweetser, 1990; G. Lakoff & Johnson, 1999. Consistent with conceptual metaphor theory in general (G. Lakoff & Johnson, 1980; G. Lakoff, 1987; Grady, 1997; Kövecses, 2000; G. Lakoff, 2009; etc., this paper’s theoretical and methodological approach is based on Sweetser’s (1990 analysis of the system of metaphors for knowledge, on G. Lakoff and Johnson’s (1999 systematic analysis of the metaphorical conceptions of Mind and Soul, and on Štrkalj Despot, Skrynnikova and Ostanina Olszewska’s (2014 comparative analysis of the metaphorical conceptions of ДУША/DUSZA/DUŠA (‘soul’ in Russian, Polish, and Croatian. The metaphors for soul were examined in a parallel corpus that consists of Dostoyevsky’s original Братья Карамазовы (The Brothers Karamazov and its Polish, Croatian and English translations. Linguistic metaphors were detected using the MIPVU procedure (Steen et al., 2010. The main questions that this paper ains to answer are: Which metaphors for conceptualizing soul are shared by all the languages in question? Which metaphors are translated differently and why? If metaphors are translated differently, is the difference conceptual, cultural or

  10. Stagnant or growing: Can management sciences evolve beyond known business challenges?

    Directory of Open Access Journals (Sweden)

    Geoff Goldman

    2011-12-01

    Full Text Available As global markets embark on some serious introspection after the global crisis of 2008, many business decision makers are asking "How did this happen?" What has become clear, however, is that we are stumbling from one business crisis to another. First it was corporate scandals such as Enron, Parmalat and Fidentia. Then came the financial crisis and the dire straits of, inter alia, Merrill Lynch, RBS, and Lehmann Brothers. Luckily, perhaps, it is not known what and when the next crisis will be. What is certain is that it will come. This begs the question: does business ever learn from what has gone before?

  11. Optimal Fermentation Conditions of Hyaluronidase Inhibition Activity on Asparagus cochinchinensis Merrill by Weissella cibaria.

    Science.gov (United States)

    Kim, Minji; Kim, Won-Baek; Koo, Kyoung Yoon; Kim, Bo Ram; Kim, Doohyun; Lee, Seoyoun; Son, Hong Joo; Hwang, Dae Youn; Kim, Dong Seob; Lee, Chung Yeoul; Lee, Heeseob

    2017-04-28

    This study was conducted to evaluate the hyaluronidase (HAase) inhibition activity of Asparagus cochinchinesis (AC) extracts following fermentation by Weissella cibaria through response surface methodology. To optimize the HAase inhibition activity, a central composite design was introduced based on four variables: the concentration of AC extract ( X 1 : 1-5%), amount of starter culture ( X 2 : 1-5%), pH ( X 3 : 4-8), and fermentation time ( X 4 : 0-10 days). The experimental data were fitted to quadratic regression equations, the accuracy of the equations was analyzed by ANOVA, and the regression coefficients for the surface quadratic model of HAase inhibition activity in the fermented AC extract were estimated by the F test and the corresponding p values. The HAase inhibition activity indicated that fermentation time was most significant among the parameters within the conditions tested. To validate the model, two different conditions among those generated by the Design Expert program were selected. Under both conditions, predicted and experimental data agreed well. Moreover, the content of protodioscin (a well-known compound related to anti-inflammation activity) was elevated after fermentation of the AC extract at the optimized fermentation condition.

  12. Induced mutation and radiation sensitivity in vitro culture of soybean (Glycine Max L. Merrill)

    International Nuclear Information System (INIS)

    Atak, C.; Alikamanoglu, S.; Yalcin, S.

    1999-01-01

    In our research, the seeds of J-357 soybean variety were irradiated with 50, 100, 200, 300 and 500 Gy of gamma rays. Callus and meristem cultures were established from the primary leaves and apical meristem of 5-day-old seeding from the irradiation seeds. The average callus fresh weight formed at the cultures were determined on the 30th day and GR 50 dose which reduces the callus fresh weight at the rate 50% in accordance with control was found as 250 Gy. The regenerated plants from meristem cultures were determined on the 28th day and LD 50 dose which decreases the regenerated plant percentage at the 50% in accordance with control was found as 220 Gy. Cytological investigation was done at the callus and meristem cultures obtained from both irradiated seeds and explants. At the seed and explant irradiations, gamma radiation dose between the ranges 50 to 200 Gy and 5 to 25 Gy; respectively were used. Observations were done at mitotic anaphase in the samples taken from meristem and callus cultures. In anaphase, two types of cytological aberrations, bridge and fragments were determined. The regenerated plants were grown in the climate chamber and the seeds were taken from each M1 plant and chlorophyll mutants were determined in M2 generation. The radiosensitivity of the meristem cultures established by irradiated seeds from view of plant regenerations and plant number which is taken seed was evaluated by comparing with the results of meristem cultures established from the irradiated explant from the point of in vitro mutation studies

  13. Different Concentrations of the Regulator Ethephon in Ripening Fruit of Jambeiro (Syzygium malaccensis, (L. Merrill & Perry

    Directory of Open Access Journals (Sweden)

    W. F. B. Demartini

    2013-11-01

    Full Text Available Evaluated the effect of concentrations of 0, 100, 250, 500 and 1000 mg L-1 ethephon (applied by immersion in maintaining the physical and chemical characteristics of the fruits of Jambeiro-red, in atmospheric conditions of Sinop-MT. Analyzed the loss of fresh weight, hydrogen potential (pH, levels of titratable acidity (AT and soluble solids (SS, over four days of exposure (DAE of fruits after harvest. The soluble solid despite increasing with time was statistically different treatments, with variations between 35.50 and 53.750 °Brix. The pH values ​​differed significantly between concentrations only for 2 DAE, with maximum concentration of 5.25 at 500 mg L-1. In general, the use of ethephon enhanced fruit color, even in unfavorable environmental conditions, however, not affect the quality of the pulp.

  14. Quality and yield response of soybean ( Glycine max L. Merrill) to ...

    African Journals Online (AJOL)

    However, plants droughted during the vegetative stage of development produced the highest yield per unit of irrigation water applied (that is, irrigation water use efficiency). This research results will be useful for maximizing soybean production and/or seed quality when irrigation water is limited. Key words: Glycine max, ...

  15. 77 FR 35104 - Notice of Request To Release Airport Property at Merrill Field Airport, Anchorage, AK

    Science.gov (United States)

    2012-06-12

    ... delivered to: Michelle Colby, Real Estate Services Manager, DOWL HKM, 4041 B Street, Anchorage, AK 99503...- 271-3665, email [email protected] or Michelle Colby, Real Estate Services Manager, DOWL HKM, 4041... Section 6.13 of the State of Alaska Right of Way Manual. This purchase offer was predicated on DOT&PF's...

  16. Chemical composition, in vitro gas production and astringency in the foliage of Samanea saman (Jacq.) Merrill

    International Nuclear Information System (INIS)

    Ojeda, A.; Barroso, J.A.; Obispo, N.; Gil, J.L.; Cegarra, R.

    2012-01-01

    In order to determine the chemical composition, astringency, in vitro gas production and ruminal degradability of the edible fraction of Samanea saman, during 2009, five samplings (February, April, May, June and October) were conducted on plants located in a semideciduous tropical forest in Venezuela. In each sampling 10 different plants were considered, each as a replicate evaluated in a completely randomized design. OM (94,1 ± 1,5%), CP (20,1 ± 1,5%), hemicellulose (17,5 ± 3,7%), cellulose (10,5 ± 2,5%), lignin (11,1 ± 1,8%), and total phenols (2,8 ± 1,1%) did not show variations (P<0,05). From May to October, the highest values (P<0,05) of EE (5,3 ± 0,8%), NDF (44,8 ± 3,3%), ADF (16,7 ± 1,9%), and Ca (1,3 ± 0,2%) were observed; while total (P<0,05) and condensed tannins (P<0,01) increased in October (3,75% and 0,99%, respectively). Astringency was not detected from February to May, and had limited values from June to October (0,4 ± 0,2 g Eta/100 g DM). No differences were observed in b (0,04 ± 0,01 mL/h), To (1,2 ± 0,2 h) and T½ (21,3 ± 3,3 h) with the highest gas potential production in February (63,3 mL/g DM). The OM and NDF degradability was reduced (P<0,05) in April (44,7% and 24,7%, respectively), without differences during the remaining months (51,2 ± 3,4% and 37,7 ± 3,3%, respectively). The edible biomass of S. saman could be used as a nutrient source in silvopastoral systems, with a low condensed tannin content of low biological activity, which causes a positive impact on the non-ammonia nitrogen flow from the rumen. (author)

  17. The human factors of sustainable building design: post occupancy evaluation of the Philip Merrill Environmental Center

    OpenAIRE

    Heerwagen, J.; Zagreus, Leah

    2005-01-01

    It is widely believed that sustainable building design strategies create improved indoor environmental quality and should, thus, be associated with improved occupant comfort, satisfaction, health, and work performance relative to buildings designed around standard practices. Yet, this belief remains a hypothesis with little empirical support. The study described in this report represents a beginning step in understanding the human factors impacts of sustainable design practices. The ...

  18. Variation in quality of individual seeds within a seed lot of soybean (Glycine max (L.) Merrill)

    NARCIS (Netherlands)

    Illipronti, R.A.

    1997-01-01

    The research described in this thesis aimed at increasing insight into the sources of variation in quality attributes of individual seeds within a soybean seed lot, into the relations between physical attributes and performance of seeds in seed tests and in controlled seed production

  19. Antioxidant activity of seedling growth in selected soybean genotypes (Glycine max (L.) Merrill) responses of submergence

    Science.gov (United States)

    Damanik, R. I.; Marbun, P.; Sihombing, L.

    2016-08-01

    In order to better understand the physiological and biochemical responses relating to direct seeding establishment in soybeans, the plant growth rate and antioxidative defense responses of seedlings in seven Indonesian soybean genotypes (Anjasmoro, Detam-1, Detam-2, Dieng, Grobogan, Tanggamus, and Willis) at different submergence periods (4, and 8 days) were examined. Twelve-day old seedlings were hydroponically grown in limited oxygen conditions. The results showed that the chlorophyll content in soybean seedlings was reduced beginning as early as 4 d under submerged condition, except for Detam-1, Detam-2, and Grobogan genotypes. The dry weight and protein concentration of seedlings were significantly higher at control condition (0 d) than those in submerged condition. The activities of superoxide dismutase (SOD) increased linearly until 8 d submerged for all genotypes. On the other hand, our results showed that catalase (CAT) and ascorbate peroxidase (APX) activities did not work together, meaning that CAT is activated and APX deactivated, or vice versa, in response to submergence conditions, except for Grobogan and Tanggamus genotypes which had an effect on both CAT and APX activities. Submergence stress led to a significant increase in glutathione reductase (GR) together with APX activity for Detam-2 and Dieng genotypes at 8 d submerged.

  20. Characterization and extraction of volatile compounds from pineapple (Ananas comosus L. Merril processing residues

    Directory of Open Access Journals (Sweden)

    Lília Calheiros de Oliveira Barretto

    2013-12-01

    Full Text Available The aim of this study was to extract and identify volatile compounds from pineapple residues generated during concentrated juice processing. Distillates of pineapple residues were obtained using the following techniques: simple hydrodistillation and hydrodistillation by passing nitrogen gas. The volatile compounds present in the distillates were captured by the solid-phase microextraction technique. The volatile compounds were identified in a system of high resolution gas chromatography system coupled with mass spectrometry using a polyethylene glycol polar capillary column as stationary phase. The pineapple residues constituted mostly of esters (35%, followed by ketones (26%, alcohols (18%, aldehydes (9%, acids (3% and other compounds (9%. Odor-active volatile compounds were mainly identified in the distillate obtained using hydrodistillation by passing nitrogen gas, namely decanal, ethyl octanoate, acetic acid, 1-hexanol, and ketones such as γ-hexalactone, γ-octalactone, δ-octalactone, γ-decalactone, and γ-dodecalactone. This suggests that the use of an inert gas and lower temperatures helped maintain higher amounts of flavor compounds. These data indicate that pineapple processing residue contained important volatile compounds which can be extracted and used as aroma enhancing products and have high potential for the production of value-added natural essences.

  1. SEED VIGOR TESTING OF SOME DOMESTIC SOYBEAN CULTIVARS (Glycine max (L. Merrill

    Directory of Open Access Journals (Sweden)

    Luka Andrić

    2004-12-01

    Full Text Available Seed ageing is an important cause of low vigor and bad field emergence, especially in adverse seedbed conditions. Therefore, in this investigation, soybean seed vigor was tested by four laboratory tests (germination energy GE, standard germination SG, cold test CT, electrical conductivity EC and in field trial, as well (early planting dates Epd and optimal planting dates Opd. The soybean seed of 5 cultivars from Agricultural Institute Osijek, produced in the 3 years (1999., 2000., 2001. was used in the investigation. The seed was stored in a warehouse conditions for 6, 18 or 30 months prior to testing. Tested soybean seed showed significant differences in seed vigor influenced by seed age, seed treatment with fungicide (Vitavax 200 FF, cultivar and planting date. High quality seed with GE and SG over 85%,performed quite well in both planting dates, as well as seeds with the CT over 70% or with EC under 42 μScm-1g-1. On the contrary, considering seed with reduced vigor there is a very great possibility of reduced FE especially in Epd. However, seed treatment with fungicide and sowing in optimal seedbed conditions can significantly contribute to improvement of soybean seed performance and stand establishment. Correlation analyses showed that all tested seed vigor parameters were significantly connected (sign. level 99%. At early planting, the strongest correlation was established between the field emergence and CT (untreated seed, r=0.949** and for treated seed r=0.951** whereas in optimal planting date was between the field emergence and SG (for untreated seed r=0. 938** and for treated seed r=0.942**. Laboratory seed health testing showed significant differences in fungal disease intensity influenced by fungicide seed treatment, cultivar and seed age. Total seed infection and infection with Fusarium spp. was adversely correlated with all vigor parameters. All tested vigor parameters of soybean seed had influence on grain yield indirectly by crop stand establishment.

  2. Effects of different boiling time of soybean ( Glycine max (L) merril ...

    African Journals Online (AJOL)

    A 56-day feeding trial was conducted with Oreochromis niloticus (Tilapia) fingerlings fed soybean boiled at different periods. The period treatment variations were unboiled soybean as control (T1); soybean seeds boiled for 20 minutes (T2); 30 minutes (T3); 40 minutes (T4) and for 50 minutes (T5). The soybean seeds so ...

  3. Effect of Drought Stress on Yield and Yield Components of Determinate Soybean (Glycine max (L Merrill

    Directory of Open Access Journals (Sweden)

    M. Abdipour

    2010-10-01

    Full Text Available The effect of drought Stress on branch and main stem yield and yield components of determinate soybean [Glycin max L. Merr], was evaluated in factorial experiment on completely randomized design with four replications at the Greenhouse of Agriculture Faculty of Shahr-e- Kord UniverSity in 2005. The experimental factors were three determinate soybean cultivars (Hutcheson, Brim and Stonewall and three drought stress levels; control; irrigate at 50% (S1; and at 25% available water (S2. Drought stress did not decrease grain yield of the main stem but decreased it in the branches severely. The highest grain yield of main stem and its contribution to total grain yield were obtained to be6.53gr, and 65.23%, for S2 and 6.21gr, 44.23% for S1 and 5.98gr, 36.04% for control treatments respectively. The highest grain yield of the branches and their contribution to total grain yield in control, S1 and S2  were obtained to be 10.61gr, 63.95%; 7.83gr, 55.76%; and 3.48gr, 34.76% respectively. Number of grains per branch was highly correlated with their grain yield , total grain yield , branch length and branch number (p

  4. Growth and quality of soybean sprouts (Glycine max L. Merrill) as affected by gamma irradiation

    Science.gov (United States)

    Soybean sprouts are considered as natural and healthy food by Asian consumers. However, sprouts are often associated with outbreaks of foodborne illnesses and recalls due to contamination of seeds with human pathogens. Irradiation may be used to inactivate pathogens on seeds and sprouts. In this stu...

  5. Merrill’s Marauders: Combined Operations in Northern Burma in 1944

    Science.gov (United States)

    1996-01-01

    area of responsibility included Burma, Ceylon, Suma - tra, Malaya-but not India or China. Reflecting the preponderance of British forces in the theater...Chiang. When Mountbatten went to Chungking, China’s wartime capital , on 16 October to meet Chiang and establish a personal relationship, he was told

  6. Effects of gamma ray irradiation on early growth of soybean (Glycine mac (L). Merrill)

    International Nuclear Information System (INIS)

    Lilik Harsanti; Yulidar

    2015-01-01

    Increase my in domestic soybean production is one of the government's program to reduce dependence on imported soybeans and soybean efforts to achieve self-sufficiency in 2015. An experiment has been conducted to study the effects of gamma ray irradiation of of 60 Cobalt on early growth of soybean seed. Variety Denna 2 varieties have been irradiated by gamma rays with 0 Gy, 200 Gy, 300 Gy, 400 Gy doses, and then planted in green house on Ps Jumat PAIR-BATAN. Plant growth from each doses is proved to be varied. From germination viability on the third day, the highest percentage of seedling with leaves is on 100 Gy dose (73.75%), and 7, 14 and 21 day the lowest is on dose 400 Gy. (author)

  7. Respons Pertumbuhan dan Produksi Kedelai (Glycine max (L.) Merril) F4 Tahan Salin terhadap Pemberian Antioksidan

    OpenAIRE

    Harahap, Rada Kurniati

    2016-01-01

    Soybean production is declining can not meet the needs of soybean in Indonesia, one of the main causes is the limited agricultural land. To increase the production of soybean in Indonesia can be reached by way of the expansion of planting areas, the use of potential land, one of which is saline soil. This study was conducted in a plastic house the Faculty of Agriculture, University of Sumatera Utara, Medan with the altitude +25 meters above sea level, from March 2016 to July 2016. The researc...

  8. (Ananas comosus (L.) Merrill) cultivées au Bénin

    African Journals Online (AJOL)

    SARAH

    31 mars 2015 ... morphotypes ont été identifiés et dénombrés à l'intérieur de 5 placeaux de 4 m2 dans chaque plantation. Les variétés d'ananas recensées sont au nombre de 5, à savoir : Cayenne lisse, Pain de sucre, Queen, Red. Spanish et Perolera. Elles renferment 16 morphotypes dont 4 pour la Cayenne lisse, ...

  9. (Glycine max L. (Merril) à l'apport des biomasses vertes de Tithonia ...

    African Journals Online (AJOL)

    SARAH

    30 mars 2013 ... des biomasses de Tithonia diversifolia (10143 kg /hectare) comme fertilisant constituerait un atout majeur pour l'accroissement des rendements du soja dans un contexte de dégradation des sols et de prix élevé des engrais minéraux. Mots clés : biomasse de Tithonia diversifolia, fumure organique, soja, ...

  10. Application of earthworm humus and Bradyrhizobium japonicum in Glycine max (L. Merrill

    Directory of Open Access Journals (Sweden)

    Ricardo Gómez Machado

    2017-10-01

    Full Text Available The experiment was developed in the Granma University's productive area, with the objective of evaluating the alone and combined earthworm humus application effect with Bradyrhizobium japonicum on G7R-315 variety soybean cultivation. Six treatments were evaluated: T1 Control, T2 B. japonicum, T3 earthworm humus (6 t ha-1, T4 B. japonicum + earthworm humus (6 t ha-1, T5 earthworm humus (8 t ha-1, T6 B. japonicum + earthworm humus (8 t ha-1 on a brown soil. A randomized block design was used with three replicas. The evaluated variables were: number per plant leguminous; weigh from 100 seeds and agricultural yield. The data obtained were processed by double classification variance analysis, applied a Turkey's multivariate statistical analysis. It was found that treatments that included the earthworm humus, the evaluated variables shown superior significantly results and it differed of the control treatment and to the aloneB. japonicum application.

  11. Application of earthworm humus and Bradyrhizobium japonicum in Glycine max (L.) Merrill

    OpenAIRE

    Ricardo Gómez Machado; Marta Travieso Torres; Luis Antonio Tamayo López; Yoannia Gretel Pupo Blanco

    2017-01-01

    The experiment was developed in the Granma University's productive area, with the objective of evaluating the alone and combined earthworm humus application effect with Bradyrhizobium japonicum on G7R-315 variety soybean cultivation. Six treatments were evaluated: T1 Control, T2 B. japonicum, T3 earthworm humus (6 t ha-1), T4 B. japonicum + earthworm humus (6 t ha-1), T5 earthworm humus (8 t ha-1), T6 B. japonicum + earthworm humus (8 t ha-1) on a brown soil. A randomized block design was use...

  12. The Film. The Bobbs-Merrill Series in Composition and Rhetoric.

    Science.gov (United States)

    Sarris, Andrew, Ed.

    Prefaced by a brief discussion of early films and film criticism, 10 essays treat selected modern directors and their works. Essays on Stanley Kubrick's "Lolita," the early works of Elia Kazan, and the response of French critics to Jerry Lewis explore the American scene, while Francois Truffaut's "Jules and Jim," the early work of Robert Bressen,…

  13. Examining Big Brother's Purpose for Using Electronic Performance Monitoring

    Science.gov (United States)

    Bartels, Lynn K.; Nordstrom, Cynthia R.

    2012-01-01

    We examined whether the reason offered for electronic performance monitoring (EPM) influenced participants' performance, stress, motivation, and satisfaction. Participants performed a data-entry task in one of five experimental conditions. In one condition, participants were not electronically monitored. In the remaining conditions, participants…

  14. The Mistreated Haiku and His Dizygotic Brother Senryu

    Science.gov (United States)

    Niece, Richard

    1978-01-01

    Haiku is a Japanese poem that deals with nature and contains seventeen syllables divided among three lines in the pattern of 5-7-5. Senryu is also a disciplined Japanese poem which deals directly with people and ideas. In Haiku, the reader utilizes imagination; in senryu, the interpretation has been supplied. Here are some creative suggestions for…

  15. Big Brother Is Watching: Video Surveillance on Buses

    Science.gov (United States)

    Sloggett, Joel

    2009-01-01

    Many school districts in North America have adopted policies to permit cameras on their properties and, when needed, on buses used to transport students. With regard to school buses, the camera is typically a tool for gathering information to monitor behavior or to help investigate a complaint about behavior. If a picture is worth a thousand…

  16. My Brother's Teacher? Siblings and Literacy Development in the Home

    Directory of Open Access Journals (Sweden)

    Laura Sokal

    2011-01-01

    Full Text Available Frequency of sibling literacy interactions were examined in 134 families with at least two children, where at least one of the children attended school in grade one to grade four. Parents in the majority of families reported that their children read together on a regular basis without a parent present. This held across various demographic constellations including gender of the older child. However, children from families with three or more children were less likely to read with their siblings. Implications for parents and teachers are discussed.

  17. Brothers at War? Reflections on an Internecine Conflict between ...

    African Journals Online (AJOL)

    1999-01-08

    Jan 8, 1999 ... Using the Ethio-Eritrean conflict as a point of reference, this paper argues that such innovations are hobbled ... become a testing ground for innovations to the internationally hatched collective security. ..... informed such efforts, who were involved and in what capacity, and what their successes and failures.

  18. French physicist's brother denies links to Al Qaeda

    CERN Document Server

    Overbye, Dennis

    2009-01-01

    "Days after the French authorities placed a physicist working in Switzerland under formal investigation in a terror case, a portrait of the man and his work has begun to emerge from interviews with officials and his lawyer"

  19. Vennalik maja = A Brotherly House / Liina Jänes

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2002-01-01

    2001. a. Tallinnas Pirita teel valminud eramu projekteeris Arhitektibüroo Emil Urbel. Arhitektid Emil Urbel ja Indrek Erm, sisearhitekt Taso Mähar. Konstruktsioonid: E-Inseneribüroo. 5 ill.: korruste plaanid, sisevaade, välisvaated

  20. Alpha-fucosidosis – Two brothers presenting with dysostosis multiplex

    African Journals Online (AJOL)

    ... progressive neurological deterioration leading to early death. Definitive diagnosis requires a-fucosidase enzyme assay or FUCA1 gene testing, which being expensive limits the definitive diagnosis in resource limited countries. We present two siblings with classic symptoms, radiological and MRI brain findings suggestive ...

  1. Siblings of Oedipus: Brothers and Sisters of Incest Victims.

    Science.gov (United States)

    de Young, Mary

    1981-01-01

    Investigates the roles and problems of siblings of incest victims, describes the dynamics of the incestuous family, and identifies some behavior problems of children whose siblings were incest victims. Data from two siblings' lives are presented to illustrate points. (Author/DB)

  2. Deconstructing Gender and Sexuality Discourses in “Brothers For ...

    African Journals Online (AJOL)

    The campaign is an attempt to promote 'new' role models for South African men in order to get to grips with one of the most serious factors behind the spread of HIV/AIDS, namely male violence against women and children. The analysis suggests that past ideals of masculinity continue to find resonance in masculinities of ...

  3. Brothers at War? Reflections on an Internecine Conflict between ...

    African Journals Online (AJOL)

    This new thinking put sub-regional organisations like ECOWAS in West Africa and SADC in Southern Africa in a good stead to take this initiative. So far, however, such initiatives in these and other sub-regions have been fraught with problems most of them insurmountable. Using the Ethio-Eritrean conflict as a point of ...

  4. The three good brothers charm : some historical points / Lea Olsan

    Index Scriptorium Estoniae

    Olsan, Lea T.

    2011-01-01

    Ravimise loitsudest: keskajal levinud legendaarsest kolme venna (tres boni fratres - lad. k.) loitsust haava parandamiseks; ettekanne rahvusvahelisel konverentsil "Charms, charmers and charming" Bukarestis 2010. a.

  5. Am I My Brother's Keeper? On Personal Identity and Responsibility ...

    African Journals Online (AJOL)

    The psychological continuity theory of personal identity has recently been accused of not meeting what is claimed to be a fundamental requirement on theories of identity – to explain personal moral responsibility. Although they often have much to say about responsibility, the charge is that they cannot say enough. I set out ...

  6. The trials of brother Jero and the Island | Agoro | International ...

    African Journals Online (AJOL)

    This paper examines the interplay of the tripartite forces inherent in the creation of artistic works. It assumes that some playwrights derive the impetus for the creation of their works from the society and argues that creative works reflect the societies on which they are based. It explores the dualistic relationship between

  7. Quantifying Systemic Risk by Solutions of the Mean-Variance Risk Model.

    Directory of Open Access Journals (Sweden)

    Jan Jurczyk

    Full Text Available The world is still recovering from the financial crisis peaking in September 2008. The triggering event was the bankruptcy of Lehman Brothers. To detect such turmoils, one can investigate the time-dependent behaviour of correlations between assets or indices. These cross-correlations have been connected to the systemic risks within markets by several studies in the aftermath of this crisis. We study 37 different US indices which cover almost all aspects of the US economy and show that monitoring an average investor's behaviour can be used to quantify times of increased risk. In this paper the overall investing strategy is approximated by the ground-states of the mean-variance model along the efficient frontier bound to real world constraints. Changes in the behaviour of the average investor is utlilized as a early warning sign.

  8. Quantifying Systemic Risk by Solutions of the Mean-Variance Risk Model.

    Science.gov (United States)

    Jurczyk, Jan; Eckrot, Alexander; Morgenstern, Ingo

    2016-01-01

    The world is still recovering from the financial crisis peaking in September 2008. The triggering event was the bankruptcy of Lehman Brothers. To detect such turmoils, one can investigate the time-dependent behaviour of correlations between assets or indices. These cross-correlations have been connected to the systemic risks within markets by several studies in the aftermath of this crisis. We study 37 different US indices which cover almost all aspects of the US economy and show that monitoring an average investor's behaviour can be used to quantify times of increased risk. In this paper the overall investing strategy is approximated by the ground-states of the mean-variance model along the efficient frontier bound to real world constraints. Changes in the behaviour of the average investor is utlilized as a early warning sign.

  9. Responsibility and Capitalism. A Phenomenological Way to Approach the Economic Crisis

    Directory of Open Access Journals (Sweden)

    Floriana Ferro

    2013-03-01

    Full Text Available The Western world is presently afflicted by a huge economic crisis, started in 2007 in the United States, with the collapse of the subprime mortgage market, and exploded in 2008 with the breakdown of Lehman Brothers[1]. Even if its most critical stage seems to be finished, capitalist countries find it difficult to recover. Globalization exported the effects of the crisis everywhere, but those that suffered the greatest damages are Europe and North America. The collapse of some financial companies is only the top of a huge iceberg. The crisis has roots in something deeper, in the principles and mechanisms of capitalism itself. The Western part of the world is still paying not for the mistakes of a few executives, but for a general lack of ethics in the whole system.

  10. The computation of dynamic fractional difference parameter for S&P500 index

    Science.gov (United States)

    Pei, Tan Pei; Cheong, Chin Wen; Galagedera, Don U. A.

    2015-10-01

    This study evaluates the time-varying long memory behaviors of the S&P500 volatility index using dynamic fractional difference parameters. Time-varying fractional difference parameter shows the dynamic of long memory in volatility series for the pre and post subprime mortgage crisis triggered by U.S. The results find an increasing trend in the S&P500 long memory volatility for the pre-crisis period. However, the onset of Lehman Brothers event reduces the predictability of volatility series following by a slight fluctuation of the factional differencing parameters. After that, the U.S. financial market becomes more informationally efficient and follows a non-stationary random process.

  11. Dynamical Analysis of Stock Market Instability by Cross-correlation Matrix

    International Nuclear Information System (INIS)

    Takaishi, Tetsuya

    2016-01-01

    We study stock market instability by using cross-correlations constructed from the return time series of 366 stocks traded on the Tokyo Stock Exchange from January 5, 1998 to December 30, 2013. To investigate the dynamical evolution of the cross-correlations, crosscorrelation matrices are calculated with a rolling window of 400 days. To quantify the volatile market stages where the potential risk is high, we apply the principal components analysis and measure the cumulative risk fraction (CRF), which is the system variance associated with the first few principal components. From the CRF, we detected three volatile market stages corresponding to the bankruptcy of Lehman Brothers, the 2011 Tohoku Region Pacific Coast Earthquake, and the FRB QE3 reduction observation in the study period. We further apply the random matrix theory for the risk analysis and find that the first eigenvector is more equally de-localized when the market is volatile. (paper)

  12. ROMANIA’S AUSTERITY POLICIES IN THE EUROPEAN CONTEXT

    Directory of Open Access Journals (Sweden)

    Todor ARPAD

    2014-06-01

    Full Text Available The economic recession starting in 2007 with the collapse of the US Bank Lehman Brothers triggered waves of economic shock across the world. Various states were hit more or less hard through different mechanisms and reacted with different intensities to adjust to the crisis situation. In this article, I employ a comparative methodology to assess the austerity policies undertook by Romania during the Great recession period as regards the policies adopted at the level of other EU member states. Thus, I aim to offer an initial evaluation of the degree of similarity of Romania’s recession policy responses to that of some other EU member states, and the degree to which Romania can be labeled as an outlier. The comparative analysis tests the explanatory power of three different theoretical approaches on the causal factors explaining variation in policy responses: power resources theories, functionalist approaches and blame-avoidance.

  13. Social Investment, Economic Growth and Labor Market Performance: Case Study—Romania

    Directory of Open Access Journals (Sweden)

    Ramona Olivia Ștefănescu-Mihăilă

    2015-03-01

    Full Text Available A few years have passed since the financial crisis began with the bankruptcy of the American Lehman Brothers bank and few dare predict the moment when we will overcome the crisis. Chaotic human resource policy in the Romanian economy and complex taxation have lowered our chances to overcome it. Excessive income tax, massive layoffs, not always dictated by real needs in the private sector, hesitation in the government regarding the reorganization of an oversized public sector and the low productivity are only some obstacles in overcoming the crisis. People are a very important factor in the production process and in the success of a company. It is essential that modern organizations rethink their strategies, make long-term investments, and invest in people. Success and survival on the market greatly depend on the understanding of these facts and managers must be aware of their importance.

  14. Frame Complexity and the Financial Crisis

    DEFF Research Database (Denmark)

    Kleinnijenhuis, Jan; Schultz, Friederike; Oegema, Dirk

    2015-01-01

    Communicative complexity concerns the variety of issues and stakeholders (agenda complexity) and their associations (frame complexity) in the news. One issue may dominate news in crises (9/11, Katrina), but as soon as complexity recovers, uncertainty may decrease and the public mood may improve....... The financial crisis in the United States, the United Kingdom, and Germany (2007–2012) offers an example. An automated content analysis was applied to over 160,000 newspaper articles. Frame complexity decreased until the spotlight fell on the demise of Bear Stearns and Lehman Brothers (2008). The subsequent...... gradual recovery was only partly interrupted by the euro crisis. A Vector AutoRegression time series analysis shows that increasing frame complexity may indeed have fostered the recovery of financial markets and consumer confidence....

  15. BASEL III AGREEMENT – BETWEEN NECESSITY AND CONVENIENCE

    Directory of Open Access Journals (Sweden)

    Florin Cornel Dumiter

    2013-03-01

    Full Text Available In the aftermath of the financial crises which started in 2007, the supervision and regulation authorities around the world dispatch the necessity of recalibration the financial and banking system. Because of the bailouts in the financial and banking sectors beyond the failure of hedge funds, mortgage bonds and the collapse of Lehman Brothers, specialists around the world looked at the necessity to underwrite the regulation and supervision frameworks. The Basel III Agreement, developed by the Basel Committee of Banking Supervision enriched a substantially revised program regarding the capital adequacy headlines. In this article, we provide an outlook regarding the necessity and conformity of the new Basel III agreement facing the challenges ahead and the upcoming threats of the ongoing financial crises.

  16. Anti-crisis monetary policy on the example of selected central banks in 2007-2011

    Directory of Open Access Journals (Sweden)

    Łukasz Kluczyński

    2015-04-01

    Full Text Available The purpose of this article was to present the actions of the monetary authorities in the light of the recent financial crisis. Destabilization of global markets and the economic recession that began with the collapse of Lehman Brothers meant that the standard monetary policy emerged ineffective in combating the crisis. The article shows how two major central banks of the world that is, the FED and the ECB, through modifying the existing instruments of monetary policy and the introduction of completely new tools tried to restore liquidity in the financial markets, after the standard monetary policy instruments have been insufficient and ineffective. In contrast, activities of the NBP also shown, which were primarily preventive aspect.

  17. An analysis of the financial crisis in the KOSPI market using Hurst exponents

    Science.gov (United States)

    Yim, Kyubin; Oh, Gabjin; Kim, Seunghwan

    2014-09-01

    Recently, the study of the financial crisis has progressed to include the concept of the complex system, thereby improving the understanding of this extreme event from a neoclassical economic perspective. To determine which variables are related to the financial event caused by the 2008 US subprime crisis using temporal correlations, we investigate the diverse variables that may explain the financial system. These variables include return, volatility, trading volume and inter-trade duration data sets within the TAQ data for 27 highly capitalized individual companies listed on the KOSPI stock market. During 2008 and 2009, the Hurst exponent for the return time series over the whole period was less than 0.5, and the Hurst exponents for other variables, such as the volatility, trading volume and inter-trade duration, were greater than 0.5. Additionally, we analyze the relationships between the variation of temporal correlation and market instability based on these Hurst exponents and the degree of multifractality. We find that for the data related to trading volume, the Hurst exponents do not allow us to detect changes in market status, such as changes from normal to abnormal status, whereas other variables, including the return, volatility and weekly inter-trade duration, indicate a significant change in market status after the Lehman Brothers' bankruptcy. In addition, the multifractality and the measurement defined by subtracting the Hurst exponent of the return time series from that of the volatility time series decrease sharply after the US subprime event and recover approximately 50 days after the Lehman Brothers' collapse. Our findings suggest that the temporal features of financial quantities in the TAQ data set and the market complexity perform very well at diagnosing financial market stability.

  18. Caracterización de la maduración del fruto de pina nativa (Ananas comosus L. Merrill CV. India Charaeterization of the ripening of pineapple (Ananas comosus L. Merrill ev. India fruit

    Directory of Open Access Journals (Sweden)

    Morales Madelaide

    2001-12-01

    Full Text Available El presente estudio tuvo como propósito caracterizar física, química y fisiológicamente el desarrollo de la maduración del fruto de piña nativa cv. India, conservado en fresco a 20°C. Durante el periodo de maduración del fruto, se encontró que la intensidad respiratoria no tuvo ningún incremento, lo que permitió clasificar al fruto como no climatérico. Este comportamiento estuvo acompañado por perdida de peso, disminución de la consistencia del mesocarpio del fruto, aumento en ácidos orgánicos, acidez, azúcares y disminución en los sólidos solubles y pH. El análisis de calidad mostró el detrimento de las características organolépticas que hacen apetecible el fruto, como son apariencia, sabor, color y aroma.This study was conducted to characterize physical, chemical
    and physiologically the development of maturation of fruit
    native pineapple cv. India, kept fresh at 20°C. During the fruit
    rnaturation, the respiratory intensity did not have any incrcase,
    which allowed to classify the fruit as non climacteric. This
    behavior was accompanied by loss of weight, decrease of
    consistency of edible fruit portion, increase in organic acids,
    acidity and sugars and decrease in soluble solids and pH.
    The quality analysis showed loss of organoleptic
    characteristics that make desirable the fruit, like appearance,
    flavor and color.

  19. Efeito do metribuzin no controle das plantas daninhas e na produção de grãos em Glycine max (L merrill Effect of metribuzin in weed control and yield of Glycine max (L. merrill

    Directory of Open Access Journals (Sweden)

    J. P. Silva Neto

    1991-01-01

    Full Text Available No ano agrícola 1985/ 86, em Viçosa-MG, foi instalado um ensaio de campo em solo Pdzólico Vermelho-Amarelo argiloso e com 2,9% de matéria orgânica, objetivando estudar o efeito das doses de metribuzin (0,0; 0,35; 0,70 e 1,05 kg i.a.ha-1 no controle de plantas daninhas e na produtividade da soja (Geycine max (L. Merri ll, cv. 'Uber aba'. A maioria das monocotiledôneas que ocorreram na area experimental foi represent ada por Cyperus rotundus L., Brachiaria plantaginea (Link Hitch. e Cynodon dactylon (L. Pers., tendo-se verificado somente redução em Brachiaria planta taginea em virtude do aumento das doses de metribuzin, ocorrendo o mesmo com relação às dicotiledôneas que se fizerem presentes no experimento, com exceção de Oxalis Oxyptera Prop., que não foi controlada nas doses utilizadas. A densidade total médias das invasoras, menos Cyperus rotundus , Oxalis oxyptera e Cynodon dactylon, foi de 141; 124; 62 e 59 plantas . m-2, respectivamente, para as doses de 0,0; 0,35 ; 0,70 e 1,05 kg i.a.ha-1 de metribuzin. A dose de 0,35 kg i.a. de metribuzin.ha-1 foi suficiente para promover a redução da matéria seca da parte aérea das plantas daninhas com a mesma eficiência de controle da dose de 1,05 kg i.a .ha-1 Entretanto, a densidade total médil das invasoras foi reduzida sig nificativamente nas doses de 0,70 e 1,05 kg i.a. de metribuzin.ha-l. O efeito do metribuzin na soja foi evidenciado somente na dose de 1,05 kg i.a.ha-1, com injúria foliar (clorose leve ocorrida até 25 dias, aproximadamente, apôs a emergência das plântulas. Após esse período, houve total recuperação de todas as plantas de soja submetidas a essa dose. A produção de grão se o índice de colheita não foram influencia dos significativamente pelas doses de metribuzin.In order to test doses of metribu zin (0,0; 0,35; 0,70 and 1,05 kg a.i.ha ¹ in weed control and yield of soybe an (Glycine max (L. Merri ll, Uberaba, an experiment was conducted under field conditions in a clayey red yellow podzolic soil with 2,9% organic matter at Viçosa, MG, during the 1985 /86 growing season. Most of the monocotyledqns species present in the experimental area consisted of Cyperus rotundus L., Brachiaria plantaginea (Link Hitch and Cynodon dactylon (L. Pers. Reduction observed was only for Brachiaria plantaginea as metribuzin doses increased, the sa me occuring with dycot iledons species existent in the area except for Oxalis oxypt era Prop. wich was not controlled by the doses using. The avera ge of the tota l weed density minus Cyper us rotundus, Oxalis oxyptera and Cynodon da+-ylon was 141, 124, 62 and 59 plants.m² for 0,0; 0,35; 0,70 and 1,05 kg a.i.ha-1 metribuzin, respectively. The lowest dose of metri buzin (0,35 kg a.i.ha-1 was as sufficient to promote reduction on weed shoot biomass at the highest did (1,05 kg a.i.ha-1. However, the mean of the total weed density was drastically recuded in the doses of 0,70 and 1,05 kg a.i.ha-1. The metribuzin caused damage to soybean plants at highest dose (1,05 kg a.i.ha-1 employed with a slight leaf injury '(chlorosis until 25 days after emergence. After this period it was observed a total recovery of the plants treat ed with this dose. The yield and the harvest index were not affected by doses of metribuzin.

  20. Comportamento de cultivares de soja [Glycine max (L. Merrill] em resposta ao metribuzin aplicado em diferentes doses Response of soybean [Glycine max (L. Merrill] cultivars to rates of metribuzin

    Directory of Open Access Journals (Sweden)

    J.A.R.O. Velloso

    1980-06-01

    Full Text Available Durante o ano agrícola de 1978/79, foi realizado um experimento a campo, na re gião da Depressão Central do Rio Grande do Sul, com o objetivo de conhecer o comportamento das cultivares de soja BR1, Bragg, Davis, IAS4, IAS5, Paraná e Planalto em relação ao metribuzin aplicado em pré-emergência nas doses de 0, 490 e 980 g/ha. Os efeitos dos tratamentos foram estimados através de avaliação visual de fitotoxicidade, contagem da população de plantas, determinações do peso seco da parte aérea e do número de grãos e obtenção do rendimento de grãos. Para a maioria das variáveis em estudo, constatou-se que ocorreram reduções proporcionais aos acréscimos das doses do herbicida. Os resultados da avaliação visual de fitotoxicidade mostraram que houve diferenças significativas entre os tratamentos de doses, tendo as cultivares Bragg e Davis demonstrado o menor efeito fito-tóxico, enquanto BR1 foi a que apresentou maior grau de injúria. Quanto ao rendimento de grãos alcançado pelas cultivares, foi constatado que Bragg comportou-se como altamente tolerante; BR1 e Davis como moderadamente tolerantes; IAS5 como intermediária e Paraná, Planalto e IAS4 como moderadamente suscetíveis.A field experiment was conducted during the 1978/79 growing season at the Central Depression Region of Rio Grande do Sul, Brazil, in order to evaluate the response soybean cultivars BR1, Bragg, Davis, IAS4, IAS5, Paraná, and Planalto to metribuzin applied in pre-emergence at rates of 0, 490 and 980 g/ha. The effects of the treatments were evaluated through visual rating of phytotoxicity, counting of soybean population, and determinations of dry weight of soybean stems, number of grains per unit area and grain yield. For most of the variables measured there were reductions proportional to increasing rates of metribuzin appl ied. Results of visual evaluation of soybean injury showed statistical differences among rates of the herbicide, being Bragg and Davis the cultivars that presented the lowest injury symptons, while BR1 showed the highest degree of phytotoxicity from metribuzin. For grain yi elds, it was determined that Bragg behaved as a highly tolerant cultivar; BR1 and Davis as moderately tolerants, IAS5 as intermediate; Paraná, Planalto and IAS 4 as moderately susceptibles.

  1. Allelopathic effects on the germination of soybean seeds (Glycine max L.Merrill/ Efeitos alelopáticos sobre a germinação de sementes de soja (Glycine max L.Merrill

    Directory of Open Access Journals (Sweden)

    Andréa Maria Teixeira Fortes

    2005-05-01

    Full Text Available This work had as objective to study the effect of natural substances found in root exsudates of other crops on the gemination of soybean seeds. Two experiments were accomplished. For the first experiment wheat seeds (Triticum aestivum, cale (Triticum sp., corn (Zea mays, ervilhaca (Vicia sativa, and black oat (Avena strigosa, that were placed to germinate, in paper rolls, in BOD at 25°C. These seeds were discarded and the papers were reused for germination of soybean seeds, using as solution-test root exsudates, and as control distilled water to humidify the paper. For the second experiment, aqueous extract of above-ground part of black oat (Avena strigosa was used to humidify the paper where the soy seeds were placed to germinate, in BOD at 25oC. Allelopatic effects alelopáticos of the root exsudates were verified on the percentage of germination of the soybean seeds, but it was not verified effect on the time and medium speed of germination. It was observed negative interference of black oat extract on the time and medium speed of soybean seeds germination.Este trabalho teve como objetivo estudar o efeito de substâncias naturais encontrados em exsudados radiculares de outras culturas, sobre a geminação da soja. Foram realizados dois experimentos: no primeiro, sementes de trigo (Triticum aestivum, triticale (Triticum sp., milho (Zea mays, ervilhaca (Vicia sativa, e aveia preta (Avena strigosa, foram colocadas para germinar, em rolos de papel, em BOD a 25°C. Estas sementes foram descartadas e os papéis reutilizados para germinação de sementes de soja, utilizando como solução-teste exsudados radiculares, e como controle apenas água destilada para umedecer os papéis. Para o segundo experimento, foi utilizado extrato aquoso da parte área de aveia preta (Avena strigosa, como umidificante do papel, onde posteriormente as sementes de soja foram colocadas para germinar, em BOD a 25oC. Constataram-se efeitos alelopáticos dos exudados radiculares, sobre a porcentagem de germinação das sementes de soja, não sendo verificado efeito sobre o tempo e velocidade média de germinação, mas verificou-se interferência negativa do extrato de aveia preta sobre o tempo e velocidade média de germinação das mesmas.

  2. Energy demand in the system sowing in different (Glycine max (L) Merril) systems planting and covering; Demanda energetica na semeadura de soja (Glycine max (L) Merril) em diferentes sistemas de manejo e cobertura do solo

    Energy Technology Data Exchange (ETDEWEB)

    Yano, Elcio Hiroyoshi [Universidade Estadual Paulista (UNESP), Ilha Solteira, SP (Brazil)], E-mail: elcio@agr.feis.unesp.br; Benez, Sergio Hugo; Silva, Paulo Roberto Arbex; Seki, Andre Satoshi [Universidade Estadual Paulista (UNESP), Botucatu, SP (Brazil); Mahl, Denise [Universidade Estadual de Maringa (UEM), Cidade Gaucha, PR (Brazil)

    2010-07-01

    The difficulty of producing quality forage associated to the high tax of decomposition of the covering killed of the soil and the low operational efficiency of agricultural machines did with that the present work was accomplished in the Experimental Farm Lageado, FCA/ UNESP of the Campus of Botucatu, on an Alsisol, with objective to analyze the energy demand requested in the soy sowing in different systems of handling of the soil (no-tillage, conventional tillage and reduced tillage), on cultural remains of black oats picked for hay, sorghum picked for humid silage of grains and spontaneous vegetation. The used experimental design was a split plot to the factorial type 3x3 with four repetitions and portions of 140 m{sup 2}, Meantime to the results, was ended that the coverings of the soil didn't influence in the values of traction force, potency, displacement speed and increase of the consumption of fuel happened and non accommodation of the turned of the tractor-seeder-fertilizer. Associate to the structural conditions of the soil as absence of traffic of machines and low index of rain fall. (author)

  3. Carboidratos das fibras de cotilédones e proteínas de produtos derivados de soja (Glycine max (L. Merril Carbohydrates from cotyledon fibers and proteins of soybean (Glycine max (L. Merril derivatives

    Directory of Open Access Journals (Sweden)

    Neusa Fátima Seibel

    2008-09-01

    Full Text Available Fibras alimentares obtidas de cotilédones de soja original (FAO e micronizada (FAM foram fracionadas e avaliadas quanto a polissacarídeos e monossacarídeos constituintes. O componente majoritário foi a hemicelulose, totalizando 59% em FAO e 51% na FAM, a pectina representou em média 14% e a celulose 8,5%. As duas amostras de fibras apresentaram 17 mg.g-1 de ácidos urônicos e a mesma composição de monossacarídeos, sendo galactose, glicose e arabinose/ramnose os principais componentes. As proteínas de concentrado protéico, farinha desengordurada e fibras alimentares (FAO e FAM foram avaliadas quanto à solubilidade em diferentes solventes (NaCl, água, etanol e NaOH e quanto ao peso molecular. A farinha desengordurada de soja teve a maior parte das proteínas passível de extração com solução salina, e o concentrado protéico e as fibras de cotilédones com solução alcalina. A fração protéica que não foi extraída com nenhum dos quatro solventes utilizados permaneceu no resíduo, o maior percentual estava no concentrado, seguido pela fibra alimentar micronizada e a farinha, já a menor quantidade estava na fibra alimentar original. A eletroforese das proteínas dos quatro ingredientes alimentares mostrou as subunidades que constituem as frações β-conglicinina e glicinina. Bandas com peso molecular próximo aos 30 kDa foram reveladas nas proteínas extraídas das fibras de cotilédones de soja, sendo provavelmente glicoproteínas de parede celular, ricas em hidroxiprolina.Dietary fibers from soybean cotyledons classified as original (ODF and milled (MDF were fractionated and evaluated as to fractions and monosaccharide composition. The major constituent was hemicellulose, 59% in ODF and 51% MDF, pectin was in average 14% and cellulose, 8.5%. Both samples had 17 mg.g-1 uronic acids and the same composition in monosaccharides: galactose, glucose and arabinose/rhamnose, after hydrolysis. Protein fractions extracted from protein concentrate, defatted flour and dietary fibers were evaluated for protein solubility in different solvents (NaCl, water, ethanol and NaOH and for molecular weight. Defatted flour had the highest concentration of proteins soluble in saline solution, while protein concentrate and dietary fibers had the highest protein solubility in alkaline solution. Residual protein, not extracted with any of the solvents used, remained in the insoluble fraction and the highest concentration was in the protein concentrate, followed by MDF, defatted flour and ODF. Protein electrophoresis of the four food ingredients showed subunits that constitute the fractions β-conglycinin and glycinin. Protein extracted from the dietary fibers showed bands with molecular weight of about 30 kDa, probably glycoproteins from cell wall material, rich in hydroxyproline.

  4. Influence of weight and type of planting material on fruit quality and its heterogeneity in pineapple [Ananas comosus (L.) Merrill

    NARCIS (Netherlands)

    Fassinou Hotegni, V.N.; Lommen, W.J.M.; Agbossou, E.K.; Struik, P.C.

    2015-01-01

    Cultural practices can affect the quality of pineapple fruits and its variation. The objectives of this study were to investigate (a) effects of weight class and type of planting material on fruit quality, heterogeneity in quality and proportion and yield of fruits meeting European export standards,

  5. POD NUMBER AND PHOTOSYNTHESIS AS PHYSIOLOGICAL SELECTION CRITERIA IN SOYBEAN (Glycine max L. Merrill BREEDING FOR HIGH YIELD

    Directory of Open Access Journals (Sweden)

    S.M. Sitompul

    2015-02-01

    Full Text Available Field studies were conducted in two years using 638 F2 and 1185 F3 lines of selected 16 F1 and 15 F2 parent lines (³80 pods plant-1 to evaluate pod number and CO2 exchange rate (CER as selection criteria. Pod and seed number, and seed weight of individual lines were observed during harvesting time, and CER of randomly selected 32 F2 and 30 F3 lines was measured at initial seed filling stage. The selection of F2 lines based on pod number to generate F3 lines increased the average of seed yield by 39%, and pod number by 77% in F3 lines compared with F2 lines. A close relationships was found between seed weight and pod or seed number per plant. Net CER responded sensitively to a reduction of light in a short-term and showed 78% of F2 lines and all F3 lines with maximum CER (Pmax³20 mmolCO2.m-2.s-1. The ratio of pod number per plant and Pmax varied between lines and were used to group lines resulting in close relationships between Pmax and pod number. It is concluded that the use of pod number and CER (Pmax as selection criteria offers an alternative approach in soybean breeding for high yield.

  6. Putative bacterial volatile-mediated growth in soybean (Glycine max L. Merrill) and expression of induced proteins under salt stress.

    Science.gov (United States)

    Vaishnav, A; Kumari, S; Jain, S; Varma, A; Choudhary, D K

    2015-08-01

    Plant root-associated rhizobacteria elicit plant immunity referred to as induced systemic tolerance (IST) against multiple abiotic stresses. Among multibacterial determinants involved in IST, the induction of IST and promotion of growth by putative bacterial volatile compounds (VOCs) is reported in the present study. To characterize plant proteins induced by putative bacterial VOCs, proteomic analysis was performed by MALDI-MS/MS after exposure of soybean seedlings to a new strain of plant growth promoting rhizobacteria (PGPR) Pseudomonas simiae strain AU. Furthermore, expression analysis by Western blotting confirmed that the vegetative storage protein (VSP), gamma-glutamyl hydrolase (GGH) and RuBisCo large chain proteins were significantly up-regulated by the exposure to AU strain and played a major role in IST. VSP has preponderant roles in N accumulation and mobilization, acid phosphatase activity and Na(+) homeostasis to sustain plant growth under stress condition. More interestingly, plant exposure to the bacterial strain significantly reduced Na(+) and enhanced K(+) and P content in root of soybean seedlings under salt stress. In addition, high accumulation of proline and chlorophyll content also provided evidence of protection against osmotic stress during the elicitation of IST by bacterial exposure. The present study reported for the first time that Ps. simiae produces a putative volatile blend that can enhance soybean seedling growth and elicit IST against 100 mmol l(-1) NaCl stress condition. The identification of such differentially expressed proteins provide new targets for future studies that will allow assessment of their physiological roles and significance in the response of glycophytes to stresses. Further work should uncover more about the chemical side of VOC compounds and a detailed study about their molecular mechanism responsible for plant growth. © 2015 The Society for Applied Microbiology.

  7. The scientific basis for modeling Northern Spotted Owl habitat: A response to Loehle, Irwin, Manly, and Merrill

    Science.gov (United States)

    Jeffrey R. Dunk; Brian Woodbridge; Elizabeth M. Glenn; Raymond J. Davis; Katherine Fitzgerald; Paul Henson; David W. LaPlante; Bruce G. Marcot; Barry R. Noon; Martin G. Raphael; Nathan H. Schumaker; Brendan. White

    2015-01-01

    The U.S. Fish and Wildlife Service recently revised the recovery plan (USFWS, 2011) and designated Critical Habitat (USFWS, 2012a) for the Northern Spotted Owl (Strix occidentalis caurina). The Critical Habitat designation was based in part on a map of relative habitat suitability that was developed by USFWS (2011, 2012b) for this purpose. Loehle...

  8. La pimienta de Jamaica [Pimenta dioica (L. Merrill, Myrtaceae] en la Sierra Norte de Puebla (México

    Directory of Open Access Journals (Sweden)

    Macía Barco, Manuel Juan

    1998-12-01

    Full Text Available Pimenta dioica, allspice, is a neotropical Myrtaceae distributed in Mesoamerica and the Caribbean region. Its área of distribution in México ranges along East and Southeast parts of the country. The main use of its dried fruits is as spice, being sold in Mexican nacional markets as well as exported to Germany, the United States, Jamaica and Great Britain. Most of the harvest comes from trees growing wild in tropical forests, although lately there is a trend to domesticate and cultivate the plant. This paper describes the propagation, domestication, harvesting, processing, marketing and socioeconomic importance of allspice in the Sierra Norte de Puebla (México. The fieldwork has been focused on Totonaca indigenous communities from this area. In these communities, allspice has medicinal use, and is used as a condiment for food; other technological and cultural uses have been also recorded. A historical monograph from Casimiro Gómez Ortega is reviewed. It includes information of the history, botany, cultivation and commerce of allspice.Pimenta dioica es una miliacea neotropical de distribución mesoamericana y caribeña. En México vive hacia el este y sudeste. Sus frutos secos se utilizan como condimento, y se trata de un producto del mercado nacional mexicano que también se exporta a Alemania, Estados Unidos, Jamaica y Reino Unido. Aunque la mayoría de la cosecha proviene de la recolección de los frutos en árboles silvestres del bosque tropical, últimamente se tiende a cultivar esta especie en un proceso actual de domesticación. Se exponen datos sobre propagación, domesticación, cosecha, procesado, mercado e importancia socioeconómica de la pimienta de Jamaica en la Sierra Norte de Puebla (México, a partir de los datos de campo obtenidos principalmente en una comunidad indígena totonaca, en donde se usa como medicinal, en alimentación y en tecnología. Además se reseña una obra de carácter histórico sobre la pimienta de Gómez Ortega, que ofrece datos históricos, botánicos, de cultivo y de comercio de esta especie.

  9. EFFECT OF PHOSPHATE ON NODULE PRIMORDIA OF SOYBEAN (Glycine max Merrill IN ACID SOILS IN RHIZOTRON EXPERIMENTS

    Directory of Open Access Journals (Sweden)

    Setiyo Hadi Waluyo

    2016-10-01

    Full Text Available To clarify whether P had a direct or indirect effect on the nodulation  process of soybean grown in acid soils from Sitiung, West Sumatra, Indonesia, a series of rhizotron experiments, with special attention given to formation of nodule primordia, was conducted at Laboratory of  Microbiology, Wageningen University in 1998-2000. It was shown that Ca and P were essential nutrients for root growth, nodule formation, and growth of soybean in the acid soils (Oxisols. Ca increased root growth, number of nodule primordia, nodules, and growth of the soybean plant. This positive effect of Ca was increased considerably by the application of P. Ca and P have a synergistic effect on biological nitrogen fixation (BNF of soybean in acid soils. Ca is important for the establishment of nodules, whilst P is essential for the development and function of the formed nodules. P increased number of nodule primordia, thus it also has an important role in the initiation of nodule formation. From this study, it can be concluded that Ca and P are the most limiting nutrients for BNF of soybean in the acid soils of Sitiung, West Sumatra, Indonesia.

  10. Physiology response of fourth generation saline resistant soybean (Glycine max (L.) Merrill) with application of several types of antioxidants

    Science.gov (United States)

    Manurung, I. R.; Rosmayati; Rahmawati, N.

    2018-02-01

    Antioxidant applications are expected to reduce the adverse effects of soil saline. This research was conducted in plastic house, Plant Tissue Laboratory Faculty of Agriculture and Plant Physiology Laboratory Faculty of Mathematic and Natural Science, Universitas Sumatera Utara, Medan also in Research Centers and Industry Standardization, Medan from July-December 2016. The objective of the research was to know the effect of various antioxidant treatments with different concentrations (control, ascorbic acid 250, 500 and 750 ppm; salicylic acid 250, 500 and 750 ppm; α-tocopherol 250, 500 and 750 ppm) on fourth generation soybean physiology in saline condition (Electric Conductivity 5-6 dS/m). The results of this research showed that the antioxidant type and concentration affected not significantly to physiology of fourth generation soybean. Descriptively the highest average of superoxide dismutase and peroxide dismutase was showed on ascorbic acid 250 ppm. The highest average of ascorbate peroxidase was showed on α-tocopherol 750 ppm. The highest average of carotenoid content was showed on ascorbic acid 500 ppm. The highest average of chlorophyll content was showed on α-tocopherol 250 ppm. The highest average of ratio of K/Na was showed on salicylic acid 250 ppm.

  11. Microbial assisted phyto extraction of metals and growth of soybean (glycine max l. merrill) on industrial waste water contaminated soil

    International Nuclear Information System (INIS)

    Ali, I.; Bano, A.

    2012-01-01

    Pots experiments were made to investigate the role of effective microorganisms (EM) in improving phyto extraction of metals (Cd/sup +2/ and Mn/sup +2/) and growth of soybean plant in industrial waste water polluted soil. Waste water applications to soil were made in four different dilutions (i.e. 25%, 50%, 75% and 100%). Effective microorganisms were added into waste water prior to application. Effect of treatments on growth parameters was studied. The Cd/sup +2/ and Mn/sup +2/ concentrations in different parts of plant were measured by Atomic Absorption Spectrophotometer. Plant height significantly increased at all treatments except at 25% waste water treatment. Plant dry biomass and oil contents in seed significantly increased with all treatments compared to control but were higher at low concentration of waste water. Waste water treatments significantly increased the Cd and Mn accumulation in plant while inoculation of EM further enhanced the metals accumulation. The maximum accumulation of Cd and Mn found in plant treated with 100% waste water in combination with effective microorganisms. At harvest, the Cd/sup +2/ concentration decreased in leaves but increased in roots followed by stem > seeds, while, Mn/sup +2/ accumulation increased in leaves followed by roots > stem > seeds. Conclusively, EM enhanced the phyto extraction of Cd and Mn and also increased the oil contents in soybean on polluted soil. These findings suggest further investigation to find out a suitable concentration of industrial waste water in combination with EM for better growth of soybean and improving phyto extraction of metals. (author)

  12. Gamma-ray induction of a mutant soybean [Glycine max (L.) Merrill] line lacking all seed lipoxygenases

    International Nuclear Information System (INIS)

    Hajika, Makita; Suda, Ikuo; Sakai, Shinji; Takahashi, Masakazu

    1997-01-01

    Induction of a soybean line lacking all isozymes of seed lipoxygenase was attempted using γ-radiation and of 1,813 seeds in M 3 generation, only one was identified as a seed lacking all the isozymes by SDS-PAGE. This line did not present any physiological abnormality over 10 generations or more (M 4 -M 14 ) and no significant influence of the enzyme on the agricultural traits was observed during the performance test in fields. In the resistance test against insect pests, significant differences were not found among the varieties and the lines tested. These results suggest that deletion of all lipoxygenase isozymes would not affect the soybean production in practice. The lipoxygenase activity was not detected in the leaves as well as the seeds of this line, suggesting that this enzyme are not indispensable for the soybean growth. The validity of this line in food processing fields was examined through determining the levels of hexanal production and DETBA. This line was found able to improve the taste of soybean cookies and use in combination with other materials as flour, egg, etc. because the line has no lipoxygenase activity. (M.N.)

  13. Effectiveness of fast neutrons irradiation for the stimulation and induction of genetic changes in soybean (Glycine max L. Merrill) genome

    International Nuclear Information System (INIS)

    Sodkiewicz, T.; Sodkiewicz, W.

    1999-01-01

    Air-dry seeds of soybean cv. Warszawska were irradiated with fast neutrons (Nf) using the U-120 cyclotron (at the Institute of Nuclear Physics in Cracow) at the doses of 500, 1000, 1500 R. Additionally, each of the irradiation doses was combined with the selected effective chemical mutagen N-nitroso-N-methylurea - in three concentrations: 0.5, 1.5 and 2.5 mM, to evaluate synergistic effect of these two different mutagenic agents. The results showed some of protection effect of radiation on the level of somatic damage of soybean plants. In addition, the phenomenon of the 'delaying effect' was noted, because the protection effect of fast neutron radiation in the combined treatments with chemomutagen was observed in the emergence and plant survival in the M 2 generation as well. From the point of view of genetic changes induced in the soybean genome, the most effective dose of fast neutron irradiation was 500 R. The number of soybean mutants with earlier ripening obtained (in comparison with original 'mother' variety) at this irradiation dose was higher, than with the highest effective concentration of chemical mutagen (1.0 -1.5 mM MNUA). (author)

  14. Germinaton performance of selected local soybean (Glycine max (L.) Merrills) cultivars during drought stress induced by Polyethylene Glycol (PEG)

    Science.gov (United States)

    Pane, R. F.; Damanik, R. I.; Khardinata, E. H.

    2018-02-01

    Drought stress is one of the factors that can decreased growth and production, so that required a variety that has the ability to sustain cellular metabolism, and growth during the stress. This research was aimed to investigated the involvement of germination performance invitro of five local soybean cultivars, Grobogan, Kaba, Anjasmoro, Argomulyo, and Dering to drought stress induced by polyethylene glycol (PEG) 6000 (0%, 2%, 4%, and 6%). The measurable seedling traits as the day appearance of shoots and roots, total of leaves, shoot length, root length, fresh plant weight, dry plant weight, fresh root weight, and dry root weight under control as well as water stress condition were recorded. The experiment units were arranged in factorial completely randomized design with four replications. The result showed that the value for most parameters was recorded highest for Argomulyo cultivar compared with Dering cultivar which is known to be tolerant to drought. In terms of roots performance, Grobogan and Argomulyo cultivars produced the longest and heaviest of roots, while Grobogan cultivar had no significant different for root length compared with control. In conclusion, the root length and fresh weight root parameters can be used as quick criteria for drought tolerance.

  15. Analysis of the Energy Performance of the Chesapeake Bay Foundation's Philip Merrill Environmental Center

    Energy Technology Data Exchange (ETDEWEB)

    Griffith, B.; Deru M.; Torcellini, P.; Ellis, P.

    2005-04-01

    The Chesapeake Bay Foundation designed their new headquarters building to minimize its environmental impact on the already highly polluted Chesapeake Bay by incorporating numerous high-performance energy saving features into the building design. CBF then contacted NREL to perform a nonbiased energy evaluation of the building. Because their building attracted much attention in the sustainable design community, an unbiased evaluation was necessary to help designers replicate successes and identify and correct problem areas. This report focuses on NREL's monitoring and analysis of the overall energy performance of the building.

  16. Potential production and growth analysis of local variety and Americana variety of soybean (Glycine max (L) Merril)

    International Nuclear Information System (INIS)

    Sumakud, M.Y.M.A.

    2000-01-01

    Soybean needs high radiation intensity for photosynthesis process; therefore 100 percent of the sunlight are needed. Due to increasing the soybean production, the environment factor such as climate, soil and management are needed. One of the environment factor that influence the growth and dry matter production is radiation. This research done was to see the potential production of local variety and Americana variety by observing the total radiation absorption, temperature, rainfall and humidity. Therefore the objective of this research was to know the potential production in tropic area in soybean. If the production is mainly determined by the high growth rate or the length of phase linear or both of them also by the efficiency of radiation that received by the plant. The method of this research was carried out by using completed randomized design, with three replications. The result showed that the growth and the production of soybean are determined by growth rate (Cm) and the length of growth linear (tm). Dry matter of soybean is determined by growth rate instead of the length of growth linear, for efficiency of radiation are not significant. Pod formation is determined by the growth rate, content of pods is determined by the length of linear growth

  17. Creating a multi-gas proxy for Delta 14C and atmospheric fossil fuel-CO2. Kevin Coakley, John Miller , Scott Lehman, Stephen Montzka, Colm Sweeney, Arlyn Andrews , Ben Miller

    Science.gov (United States)

    Coakley, K. J.; Miller, J. B.; Lehman, S.; Montzka, S. A.; Andrews, A. E.; Miller, B. R.

    2013-12-01

    The C14:C12 ratio of atmospheric CO2 (expressed as Delta 14C) is the gold standard measurement to derive the portion of observed atmospheric CO2 gradients resulting from combustion of fossil fuels (CO2-ff). This is because fossil fuels are devoid of 14C, unlike all other sources and sinks that impact atmospheric Delta14C. With enough 14C measurements, independent, 'top-down', estimation of US fossil fuel-CO2 emissions should be possible. However, our ability to make carbon-14 measurements is severely constrained by cost, accessibility to accelerator mass spectrometers (AMS) and the volume of air required to make high precision (~0.2 %) measurements of 14CO2 (mixing ratio is ~ 4e-16 mol/mol). Thus, Delta 14C is currently measured in only a small subset of NOAA/ESRL Global Monitoring Division (GMD) tall-tower and aircraft air samples. Here, we present a Projection Pursuit Regression (PPR) model to predict CO2-ff measured at different times and altitudes in terms of surrogate gases that are more widespread and relatively inexpensive to measure. This method would, in effect, allow expansion of Delta 14C measurements by factor of ~3 or 4 throughout North America. To create a proxy for CO2-ff, we take advantage of the observed correlations between (Delta 14C-derrived) CO2-ff and regional-scale enhancements of a wide array of anthropogenic gases, like CO, SF6, and halo- and hydro-carbons. We select the complexity and form of the PPR model by cross validation where validation data prediction error is minimized. In cross validation, the prediction model is based on the training data and not the validation data. We quantify prediction model performance with test data excluded from the model development process. According to cross validation, the PPR model is superior to a simpler linear model. Comparison with test CO2-ff data shows that CO2-ff can be predicted with a root mean square error of 1.1 ppm, only slightly higher than the Delta 14C-precision limit for CO2-ff of 1 ppm. Applying the PPR model to the large NOAA/ESRL/GMD database of surrogate gases, we can create a large set of synthetic CO2-ff data for the US. Finally, we will discuss the application of this large data set of lower-precision CO2-ff to top down determination of US fossil fuel CO2 emissions by presenting results from an Observation System Simulation Experiment (OSSE).

  18. Beyond Bad Behaving Brothers: Productive Performances of Masculinities among College Fraternity Men

    Science.gov (United States)

    Harris, Frank, III; Harper, Shaun R.

    2014-01-01

    Research on fraternity men focuses almost exclusively on problematic behaviors such as homophobia and sexism, alcohol abuse, violence against women, sexual promiscuity, and the overrepresentation of members among campus judicial offenders. Consequently, little is known about those who perform masculinities in healthy and productive ways. Presented…

  19. Two Silent Brothers. Althusser and Foucault at the Crossroads of Ideology

    Directory of Open Access Journals (Sweden)

    Diego Melegari

    2014-07-01

    Full Text Available The article aims to reinterpret the relationship between Louis Althusser and Michel Foucault on the specific ground of the notion of "Ideology." If Foucault's critique addresses initially the alleged opposition between ideological discourse and scientific discourse, this does not seem to fade in the seventies, despite the convergence of Foucault's "microphysics of power"with Althusser's insistence on the "material" character of ideology. To explain the persistence of this comparison and of this tension the author shows how with it are involved highly problematic knots for the whole Foucault's thought: the status of representation and truth, the inner existence and temporality of capitalism and, in particular, the relationship between criticism and politics.

  20. The tale of the three brothers - Shh, Wnt and Fgf during development of the thalamus

    Directory of Open Access Journals (Sweden)

    Anja IH Hagemann

    2012-05-01

    Full Text Available The thalamic complex is an essential part of the brain that requires a combination of specialized activities to attain its final complexity. In the following review we will describe the induction process of the mid-diencephalic organizer (MDO where three different signaling pathways merge: Wnt, Shh and Fgf. Here, we dissect the function of each signaling pathway in the thalamus in chronological order of their appearance. First we describe the Wnt mediated induction of the MDO and compartition of the caudal forebrain, then the Shh mediated determination of proneural gene expression before discussing recent progress in characterizing Fgf function during thalamus development. Then, we focus on transcription factors, which are regulated by these pathways and which play a pivotal role in neurogenesis in the thalamus. The three signaling pathways act together in a strictly regulated chronology to orchestrate the development of the entire thalamus.

  1. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    Walsh, Aisling

    2010-09-17

    Abstract Background Considerable attention has been given by policy makers and researchers to the human resources for health crisis in Africa. However, little attention has been paid to quantifying health facility-level trends in health worker numbers, distribution and workload, despite growing demands on health workers due to the availability of new funds for HIV\\/AIDS control scale-up. This study analyses and reports trends in HIV and non-HIV ambulatory service workloads on clinical staff in urban and rural district level facilities. Methods Structured surveys of health facility managers, and health services covering 2005-07 were conducted in three districts of Zambia in 2008 (two urban and one rural), to fill this evidence gap. Intra-facility analyses were conducted, comparing trends in HIV and non-HIV service utilisation with staff trends. Results Clinical staff (doctors, nurses and nurse-midwives, and clinical officers) numbers and staff population densities fell slightly, with lower ratios of staff to population in the rural district. The ratios of antenatal care and family planning registrants to nurses\\/nurse-midwives were highest at baseline and increased further at the rural facilities over the three years, while daily outpatient department (OPD) workload in urban facilities fell below that in rural facilities. HIV workload, as measured by numbers of clients receiving antiretroviral treatment (ART) and prevention of mother to child transmission (PMTCT) per facility staff member, was highest in the capital city, but increased rapidly in all three districts. The analysis suggests evidence of task sharing, in that staff designated by managers as ART and PMTCT workers made up a higher proportion of frontline service providers by 2007. Conclusions This analysis of workforce patterns across 30 facilities in three districts of Zambia illustrates that the remarkable achievements in scaling-up HIV\\/AIDS service delivery has been on the back of sustained non-HIV workload levels, increasing HIV workload and stagnant health worker numbers. The findings are based on an analysis of routine data that are available to district and national managers. Mixed methods research is needed, combining quantitative analyses of routine health information with follow-up qualitative interviews, to explore and explain workload changes, and to identify and measure where problems are most acute, so that decision makers can respond appropriately. This study provides quantitative evidence of a human resource crisis in health facilities in Zambia, which may be more acute in rural areas.

  2. Siblings: Brothers and Sisters of People Who Have Mental Retardation. Arc Q & A Series.

    Science.gov (United States)

    Arc, Arlington, TX.

    Basic information about siblings of people with mental retardation is presented in a question-and-answer format. The following questions are addressed: "Is having a sibling with a disability different than having a sibling who does not have a disability?"; "What are some of the concerns of siblings of people with disabilities?"; "Are there any…

  3. A designated centre for people with disabilities operated by Brothers of Charity Services Galway - Galway

    LENUS (Irish Health Repository)

    Golabek, Tomasz

    2013-07-22

    To compare urodynamic characteristics in patients with idiopathic detrusor overactivity (IDO) with those of an age matched cohort with diabetes mellitus (DM) and detrusor overactivity (DO). Secondly, to determine whether urodynamic features could help distinguish these two groups of patients.

  4. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    O'Shea, Eamon

    2011-02-14

    Abstract Background Current projections indicate that there will be a significant increase in the number of people with dementia in Ireland, from approximately 40,000 at present to 100,000 by 2036. Psychosocial interventions, such as reminiscence, have the potential to improve the quality of life of people with dementia. However, while reminiscence is used widely in dementia care, its impact on the quality of life of people with dementia remains largely undocumented and there is a need for a robust and fair assessment of its overall effectiveness. The DementiA education programme incorporating REminiscence for Staff study will evaluate the effectiveness of a structured reminiscence-based education programme for care staff on the quality of life of residents with dementia in long-stay units. Methods\\/Design The study is a two-group, single-blind cluster randomised trial conducted in public and private long-stay residential settings in Ireland. Randomisation to control and intervention is at the level of the long-stay residential unit. Sample size calculations suggest that 18 residential units each containing 17 people with dementia are required for randomisation to control and intervention groups to achieve power of at least 80% with alpha levels of 0.05. Each resident in the intervention group is linked with a nurse and care assistant who have taken the structured reminiscence-based education programme. Participants in the control group will receive usual care. The primary outcome is quality of life of residents as measured by the Quality of Life-AD instrument. Secondary outcomes include agitation, depression and carer burden. Blinded outcome assessment is undertaken at baseline and at 18-22 weeks post-randomisation. Discussion Trials on reminiscence-based interventions for people with dementia have been scarce and the quality of the information arising from those that have been done has been undermined by methodological problems, particularly in relation to scale and scope. This trial is powered to deliver more credible and durable results. The trial may also convey process utility to a long-stay system in Ireland that has not been geared for education and training, especially in relation to dementia. The results of this trial are applicable to long-stay residential units in Ireland and internationally. Trial registration Current Controlled Trials ISRCTN99651465

  5. Phelan-McDermid syndrome in two adult brothers: Atypical bipolar disorder as its psychopathological phenotype?

    NARCIS (Netherlands)

    W.M.A. Verhoeven (Wim); J.I.M. Egger (Jos); M.H. Willemsen; G.J.M. de Leijer (Gert); T. Kleefstra (Tjitske)

    2012-01-01

    textabstractThe 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep

  6. Phelan-McDermid syndrome in two adult brothers: Atypical bipolar disorder as its psychopathological phenotype?

    NARCIS (Netherlands)

    Verhoeven, W.M.A.; Egger, J.I.M.; Willemsen, M.H.; Leijer, G.J.M. de; Kleefstra, T.

    2012-01-01

    The 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep disturbances,

  7. Phelan-McDermid syndrome in two adult brothers: atypical bipolar disorder as its psychopathological phenotype?

    NARCIS (Netherlands)

    Verhoeven, W.M.; Egger, J.I.; Willemsen, M.H.; de Leijer, G.J.; Kleefstra, T.

    2012-01-01

    The 22q13.3 deletion, or Phelan-McDermid syndrome, is characterized by global intellectual disability, generalized hypotonia, severely delayed or absent speech associated with features of autism spectrum disorder, and minor dysmorphisms. Its behavioral phenotype comprises sleep disturbances,

  8. Adjustment, Sibling Problems and Coping Strategies of Brothers and Sisters of Children with Autistic Spectrum Disorder

    Science.gov (United States)

    Ross, Penelope; Cuskelly, Monica

    2006-01-01

    Background: Siblings of children with autistic spectrum disorder (ASD) express more problem behaviours and experience more difficulties in their relationships than do children in families where all children are developing typically. We know little about what contributes to these difficulties. Method: Mothers of a child with ASD completed the…

  9. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Fogarty, Emer

    2014-09-01

    Multiple sclerosis (MS) has significant financial consequences for healthcare systems, individual patients and households, and the wider society. This study examines the distribution of MS costs and resource utilisation across cost categories and from various perspectives, as MS disability increases.

  10. Posterior Ankle Impingement in Two Athletic Twin Brothers, Could Genetics Play a Role?

    NARCIS (Netherlands)

    Bech, Niels H.; de Leeuw, Peter A. J.; Haverkamp, Daniel

    2016-01-01

    Pain posteriorly in the ankle can be caused by bony impingement of the posterolateral process of the talus. This process impinges between the tibia and calcaneus during deep forced plantar flexion. If this occurs it is called posterior ankle impingement syndrome. We report the case of 2 athletic

  11. My Brother’s Keeper: Forging SOF Operators Through Developmental Relationships

    Science.gov (United States)

    2016-06-01

    business-oriented literature focuses on examining the effects of mentoring, peer coaching, and developmental networks on career mobility and 5...figuring out the direction of the team. The pendulum has swung too far to one side. Where’s our focus? Regionally? Skill set? All that changes who you get...Relations, 66. Scandura, T. A. (1992). Mentorship and career mobility : An empirical investigation. Journal of Organizational Behavior, 13, 169–174

  12. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Holton, Alice E

    2017-11-08

    Older adults are particularly vulnerable to adverse effects from concurrent alcohol and medication use. However, there is limited evidence regarding the prevalence of these adverse outcomes among older adults, and there is a lack of consensus regarding what constitutes an alcohol-interactive medicine. The objective of this study was to develop an explicit list of potentially serious alcohol-medication interactions for use in older adults.

  13. Deconstructing gender and sexuality discourses in “Brothers for Life ...

    African Journals Online (AJOL)

    of social relations are relative to the spatial-temporal narrative envelope, and thus provides a means to discuss depictions of masculinity across time and space (Agha 2007). Importantly, the interpersonal experience of a chronotope and the way in which the personae in space-time are construed derive from the participation ...

  14. O PROCESSO CRIATIVO EM THE BROTHER, DE ROBERT COOVER: UMA RELEITURA DO SAGRADO NA CONTEMPORANEIDADE

    Directory of Open Access Journals (Sweden)

    Fernanda Aquino Sylvestre

    2014-05-01

    Full Text Available Robert Coover é um importante escritor norte-americano preocupado com as perspectivas sociais, psicológicas, econômicas e políticas contemporâneas e com o modo como elas se configuram na formação da sociedade do seu país. Essa preocupação se reflete tanto nas técnicas de construção de suas histórias, quanto nas críticas apresentadas em suas narrativas. O trabalho em questão discute a reescrita que Coover faz de mitos bíblicos dentro do contexto pós-moderno, globalizado, compondo novos textos que subvertem os elementos tradicionais da narrativa. Mais especificamente, este artigo analisa a reescrita que o autor norte-americano empreende acerca da passagem bíblica da Arca de Noé no conto “The Brother”.

  15. Back-breeding the aurochs: the Heck brothers, National Socialism and imagined geographies for nonhuman Lebensraum

    NARCIS (Netherlands)

    Driessen, C.P.G.; Lorimer, J.

    2016-01-01

    This chapter investigates the bio-geographical imaginations behind the animal 'back-breeding' programs carried out by Lutz and Heinz Heck - two influential German zoologists who ran Berlin and Munich zoos. Partly with close connections to and patronage from the National Socialist elite, the Heck

  16. A designated centre for people with disabilities operated by Brothers of Charity Services Limerick, Limerick

    LENUS (Irish Health Repository)

    O Caoimh, Rónán

    2014-09-19

    Functional decline and frailty are common in community dwelling older adults, increasing the risk of adverse outcomes. Given this, we investigated the prevalence of frailty-associated risk factors and their distribution according to the severity of perceived risk in a cohort of community dwelling older adults, using the Risk Instrument for Screening in the Community (RISC).

  17. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Clare

    LENUS (Irish Health Repository)

    1986-01-01

    Please note that this handbook was written in the 1990s and information may have been superceded with more recent publications. Please check the Alzheimer\\'s Society of Ireland website for the most up to date versions of documents. This document is made available here for achival purposes.

  18. When big brother is watching: goal orientation shapes reactions to electronic monitoring during online training.

    Science.gov (United States)

    Watson, Aaron M; Foster Thompson, Lori; Rudolph, Jane V; Whelan, Thomas J; Behrend, Tara S; Gissel, Amanda L

    2013-07-01

    Web-based training is frequently used by organizations as a convenient and low-cost way to teach employees new knowledge and skills. As web-based training is typically unproctored, employees may be held accountable to the organization by computer software that monitors their behaviors. The current study examines how the introduction of electronic performance monitoring may provoke negative emotional reactions and decrease learning among certain types of e-learners. Through motivated action theory and trait activation theory, we examine the role of performance goal orientation when e-learners are exposed to asynchronous and synchronous monitoring. We show that some e-learners are more susceptible than others to evaluation apprehension when they perceive their activities are being monitored electronically. Specifically, e-learners higher in avoid performance goal orientation exhibited increased evaluation apprehension if they believed asynchronous monitoring was present, and they showed decreased skill attainment as a result. E-learners higher on prove performance goal orientation showed greater evaluation apprehension if they believed real-time monitoring was occurring, resulting in decreased skill attainment. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  19. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    Ohmann, Christian

    2011-03-22

    Abstract Background A recent survey has shown that data management in clinical trials performed by academic trial units still faces many difficulties (e.g. heterogeneity of software products, deficits in quality management, limited human and financial resources and the complexity of running a local computer centre). Unfortunately, no specific, practical and open standard for both GCP-compliant data management and the underlying IT-infrastructure is available to improve the situation. For that reason the "Working Group on Data Centres" of the European Clinical Research Infrastructures Network (ECRIN) has developed a standard specifying the requirements for high quality GCP-compliant data management in multinational clinical trials. Methods International, European and national regulations and guidelines relevant to GCP, data security and IT infrastructures, as well as ECRIN documents produced previously, were evaluated to provide a starting point for the development of standard requirements. The requirements were produced by expert consensus of the ECRIN Working group on Data Centres, using a structured and standardised process. The requirements were divided into two main parts: an IT part covering standards for the underlying IT infrastructure and computer systems in general, and a Data Management (DM) part covering requirements for data management applications in clinical trials. Results The standard developed includes 115 IT requirements, split into 15 separate sections, 107 DM requirements (in 12 sections) and 13 other requirements (2 sections). Sections IT01 to IT05 deal with the basic IT infrastructure while IT06 and IT07 cover validation and local software development. IT08 to IT015 concern the aspects of IT systems that directly support clinical trial management. Sections DM01 to DM03 cover the implementation of a specific clinical data management application, i.e. for a specific trial, whilst DM04 to DM12 address the data management of trials across the unit. Section IN01 is dedicated to international aspects and ST01 to the competence of a trials unit\\'s staff. Conclusions The standard is intended to provide an open and widely used set of requirements for GCP-compliant data management, particularly in academic trial units. It is the intention that ECRIN will use these requirements as the basis for the certification of ECRIN data centres.

  20. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Ward, M

    2009-01-08

    In November and December 2008, six cases of suspect wound botulism were reported in heroin injecting drug users, all residents in Dublin, Ireland. Patients were aged between 23-42 years of age; four cases were male; one patient died shortly after admission. The patients presented to four different hospitals across the city. Botulism in injecting drug users in Ireland was last reported in 2002.

  1. An evaluation of the doctrine of miraculous healing within the Roman Catholic tradition / Brother James Scott

    OpenAIRE

    Scott, James

    2006-01-01

    According to biblical record, diseases and illness have troubled individuals almost since the beginning of creation (Wilkinson, 1998: 7). To understand and make sense of sickness, mankind turned to religion. In the Old Testament health is seen as a gift of God, but illness is perceived as a punishment for sin (Leon-Dufour, 1962: 543). The preaching of Job argues against this view. The problem of evil still causes difficulties for the Christian today. God permits such challen...

  2. Brothers or Rivals? Iran and the Shi'a of Iraq

    National Research Council Canada - National Science Library

    Hunter, Robert C

    2006-01-01

    This thesis examines the loyalty of the Shi a of Iraq. While some Sunni Arab leaders have recently accused the Shi a of Iraq of pledging loyalty to Iran, in fact the Iraqi Shi a are loyal to their own nation...

  3. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    O’Connell, Emer

    2016-07-01

    Patient safety requires optimal management of medications. Electronic systems are encouraged to reduce medication errors. Near field communications (NFC) is an emerging technology that may be used to develop novel medication management systems.

  4. Band of Brothers or Dysfunctional Family? A Military Perspective on Coalition Challenges During Stability Operations

    Science.gov (United States)

    2011-01-01

    was, in many cases, the commercial world’s managers and civilian economic geniuses who deserve much of the credit for success. Unfortu- nately, we do...conventional wartime combat, once the adversary has been defeated. Some erstwhile partners lack a unifying compulsion of suffi- cient importance to... card —i.e., refusing to obey due to the nation-specific caveat. Despite the NATO nations having worked together for many years, none suffered a

  5. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    O'Daly, Brendan J

    2009-06-01

    BACKGROUND: Predicting the clinical course in adhesional small bowel obstruction is difficult. There are no validated clinical or radiologic features that allow early identification of patients likely to require surgical intervention. METHODS: We conducted a retrospective review of 100 patients consecutively admitted to a tertiary level teaching hospital over a 3-year period (2002-2004) who had acute adhesional small bowel obstruction and underwent computed tomography (CT). The primary outcomes that we assessed were conservative management or the need for surgical intervention. We investigated time to physiologic gastrointestinal function recovery as a secondary outcome. We examined independent predictors of surgical intervention in a bivariate analysis using a stepwise logistic regression analysis. RESULTS: Of the 100 patients investigated, we excluded 12. Of the 88 remaining patients, 58 (66%) were managed conservatively and 30 (34%) underwent surgery. Peritoneal fluid detected on a CT scan (n = 37) was associated more frequently with surgery than conservative management (46% v. 29%, p = 0.046, chi(2)). Logistical regression identified peritoneal fluid detected on a CT scan as an independent predictor of surgical intervention (odds ratio 3.0, 95% confidence interval 1.15-7.84). CONCLUSION: The presence of peritoneal fluid on a CT scan in patients with adhesional small bowel obstruction is an independent predictor of surgical intervention and should alert the clinician that the patient is 3 times more likely to require surgery.

  6. DOSTOEVSKY'S CONCEPT OF HOLY BODY IN THE STRUCTURE OF "THE BROTHERS KARAMAZOV" (RELIGIOUS AND AESTHETIC ASPECTS

    Directory of Open Access Journals (Sweden)

    Natalia Zhivolupova

    2012-12-01

    Full Text Available The problem of the aesthetic and philosophical significance of the body in Dostoevsky’s creative writing is intimately connected with the structure of his formally intricate novels. The inner structure of Dostoevsky's novels illuminates the representation of the body in his opus as an innate part of Dostoevsky's poetics. The concept of the body includes an aesthetic as well as philosophical spectrum of problems, to which the interest in the topic from both literary critics and philosophers attests.

  7. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    O'Higgins, A

    2014-11-01

    The provision of high quality healthcare information about pregnancy is important to women and to healthcare professionals and it is 1 driven, in part, by a desire to improve clinical outcomes,. The objective of this study was to examine the use of digital media by women\\' to access pregnancy information. A questionnaire was distributed to women attending a large maternity hospital. Of the 522 respondents, the mean age was 31.8 years, 45% (235\\/522) were nulliparous, 62% (324\\/522) lived in the capital city and 29% (150\\/522) attended the hospital as private patients. Overall 95% (498\\/522) used the internet for pregnancy information, 76% (399\\/522) had a smartphone and 59% (235\\/399) of smartphone owners had used a pregnancy smartapp. The nature of internet usage for pregnancy information included discussion forums (70%), social networks (67%), video media (48%), e-books (15%), blogs (13%), microblogs (9%) and podcasts (4%). Even women who were socially disadvantaged reported high levels of digital media usage. In contemporary maternity care women use digital media extensively for pregnancy information. All maternity services should have a digital media strategy.

  8. TALKING POLITICS ONLINE WITHIN SPACES OF POPULAR CULTURE : THE CASE OF THE BIG BROTHER FORUM

    NARCIS (Netherlands)

    Graham, T.S.

    2010-01-01

    Talking politics online is not bound to spaces dedicated to politics, particularly the everyday political talk crucial to the public sphere. The aim of this article is to move beyond such spaces by examining political talk within a space dedicated to popular culture. The purpose is to see whether a

  9. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Murphy, Andrew W

    2005-07-29

    BACKGROUND: The aim of the SPHERE study is to design, implement and evaluate tailored practice and personal care plans to improve the process of care and objective clinical outcomes for patients with established coronary heart disease (CHD) in general practice across two different health systems on the island of Ireland. CHD is a common cause of death and a significant cause of morbidity in Ireland. Secondary prevention has been recommended as a key strategy for reducing levels of CHD mortality and general practice has been highlighted as an ideal setting for secondary prevention initiatives. Current indications suggest that there is considerable room for improvement in the provision of secondary prevention for patients with established heart disease on the island of Ireland. The review literature recommends structured programmes with continued support and follow-up of patients; the provision of training, tailored to practice needs of access to evidence of effectiveness of secondary prevention; structured recall programmes that also take account of individual practice needs; and patient-centred consultations accompanied by attention to disease management guidelines. METHODS: SPHERE is a cluster randomised controlled trial, with practice-level randomisation to intervention and control groups, recruiting 960 patients from 48 practices in three study centres (Belfast, Dublin and Galway). Primary outcomes are blood pressure, total cholesterol, physical and mental health status (SF-12) and hospital re-admissions. The intervention takes place over two years and data is collected at baseline, one-year and two-year follow-up. Data is obtained from medical charts, consultations with practitioners, and patient postal questionnaires. The SPHERE intervention involves the implementation of a structured systematic programme of care for patients with CHD attending general practice. It is a multi-faceted intervention that has been developed to respond to barriers and solutions to optimal secondary prevention identified in preliminary qualitative research with practitioners and patients. General practitioners and practice nurses attend training sessions in facilitating behaviour change and medication prescribing guidelines for secondary prevention of CHD. Patients are invited to attend regular four-monthly consultations over two years, during which targets and goals for secondary prevention are set and reviewed. The analysis will be strengthened by economic, policy and qualitative components.

  10. 75 FR 46864 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

    Science.gov (United States)

    2010-08-04

    ... 9DZ Northern Ireland; telephone +44(0)2890-462469; fax +44(0)2890- 468444; e-mail michael.mulholland.... Revision History: PAD [proposed airworthiness directive] 06- 018R1 has been issued to endorse comments...

  11. Mothers' Differential Treatment of Adolescent Siblings: Predicting College Attendance of Sisters versus Brothers

    Science.gov (United States)

    Bissell-Havran, Joanna M.; Loken, Eric; McHale, Susan M.

    2012-01-01

    Current estimates suggest that by 2015, 60% of college students will be women, a change since 1970 when 59% were men. We investigated family dynamics that might explain the growing gender gap in college attendance, focusing on an ethnically diverse sample of 522 mixed sex sibling dyads from the National Longitudinal Study of Adolescent Health. We…

  12. The zombie and his italian half brother: the satiric use of the zombie ...

    African Journals Online (AJOL)

    ... italiana degli anni Novanta, caratterizzata da un consumismo banale e popolata di giovani ossessionati dalla moda e dalla pubblicità. Il saggio si propone di analizzare il racconto nell'ambito del pulp italiano definendone le originali tecniche di demistificazione. Key Words: Pulp Fiction – Gothic Novel – Consumerism ...

  13. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    O'Reilly, Martina

    2016-07-01

    Assessment in palliative care settings should be focused, sensitive, specific, and effective to minimize discomfort to vulnerable and often highly morbid patients. This report describes the development of an admission assessment protocol for a Specialist Palliative Care Inpatient Unit and its implementation into clinical practice.

  14. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    Falush, Daniel

    2009-10-01

    Bacteria evolve rapidly in response to the environment they encounter. Some environmental changes are experienced numerous times by bacteria from the same population, providing an opportunity to dissect the genetic basis of adaptive evolution. Here I discuss two examples in which the patterns of rapid change provide insight into medically important bacterial phenotypes, namely immune escape by Neisseria meningitidis and host specificity of Campylobacter jejuni. Genomic analysis of populations of bacteria from these species holds great promise but requires appropriate concepts and statistical tools.

  15. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Limerick

    LENUS (Irish Health Repository)

    Hegarty, M

    2010-11-01

    As increasing demand for organs is a challenge for transplant services worldwide it is essential to audit the process of organ donation. To address this, a national audit of potential organ donors was undertaken across hospitals with Intensive Care Units (N = 36). Questionnaires were returned on all patients (n = 2073) who died in these units from 1\\/9\\/07-31\\/8\\/08; 200 (10%) of these patients were considered for Brain Stem Testing (BST), 158 patients (79%) were diagnosed Brain Stem Dead (BSD) and 138 patients (87%) became potential donors. Consent for donation was given by 92 (69%) next of kin and 90 potential donors (65%) became organ donors. There was no evidence of a large number of potential organ donors being missed. Recommendations included completion of BSTs on all appropriate patients, development of support on BST, referral of all BSD patients to the Organ Procurement Service; enhanced co-ordination within hospitals and sustained information\\/education campaigns.

  16. The Brothers and Sisters Learn To Write: Popular Literacies in Childhood and School Cultures.

    Science.gov (United States)

    Dyson, Anne Haas

    Building on the author's groundbreaking work in "Building Superheroes," this book traces the influence of a wide-ranging set of "textual toys" from children's lives--church and hip-hop songs, rap music, movies, TV, traditional jump-rope rhymes, the words of professional sports announcers and radio deejays--upon school learning…

  17. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    Clarke, Ciaran

    2015-05-01

    Among the core features of ASD, altered sensitivities in all modalities have been accorded increasing importance. Heightened sensitivity to pain and unusual expressions of and reaction to pain have not hitherto been widely recognised as a presenting feature of ASD in general paediatrics. Failure to recognise ASD as a common cause of pain can lead to late diagnosis, inappropriate treatment, distress, and further disability. Two cases are presented which illustrate the late presentation of Autism Spectrum Disorder (Asperger\\'s Syndrome subtype) with chronic unusual pain. Conclusion. Pain in autism can be atypical in its experience and expression and for this reason may go unrecognised by physicians treating chronic pain disorders.

  18. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    O'Caoimh, Rónán

    2015-09-01

    Few case-finding instruments are available to community healthcare professionals. This review aims to identify short, valid instruments that detect older community-dwellers risk of four adverse outcomes: hospitalisation, functional-decline, institutionalisation and death. Data sources included PubMed and the Cochrane library. Data on outcome measures, patient and instrument characteristics, and trial quality (using the Quality In Prognosis Studies [QUIPS] tool), were double-extracted for derivation-validation studies in community-dwelling older adults (>50 years). Forty-six publications, representing 23 unique instruments, were included. Only five were externally validated. Mean patient age range was 64.2-84.6 years. Most instruments n=18, (78%) were derived in North America from secondary analysis of survey data. The majority n=12, (52%), measured more than one outcome with hospitalisation and the Probability of Repeated Admission score the most studied outcome and instrument respectively. All instruments incorporated multiple predictors. Activities of daily living n=16, (70%), was included most often. Accuracy varied according to instruments and outcomes; area under the curve of 0.60-0.73 for hospitalisation, 0.63-0.78 for functional decline, 0.70-0.74 for institutionalisation and 0.56-0.82 for death. The QUIPS tool showed that 5\\/23 instruments had low potential for bias across all domains. This review highlights the present need to develop short, reliable, valid instruments to case-find older adults at risk in the community.

  19. A designated centre for people with disabilities operated by Brothers of Charity Services Limerick, Longford

    LENUS (Irish Health Repository)

    Masud, Tahir

    2014-09-01

    the rise in the number of older, frail adults necessitates that future doctors are adequately trained in the skills of geriatric medicine. Few countries have dedicated curricula in geriatric medicine at the undergraduate level. The aim of this project was to develop a consensus among geriatricians on a curriculum with the minimal requirements that a medical student should achieve by the end of medical school.

  20. Big Brother Is Helping You: Supporting Self-Access Language Learning with a Student Monitoring System

    Science.gov (United States)

    Reinders, Hayo

    2007-01-01

    Self-access and language advising are relatively recent and increasingly common types of language support offered in schools and tertiary institutions around the world. There is a great deal of anecdotal support for the positive contribution of such support to student learning. Self-access and language advising hold strong potential as…

  1. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Buckley, B S

    2011-12-12

    Background:  Gestational diabetes mellitus is a potentially serious condition that affects many pregnancies and its prevalence is increasing. Evidence suggests early detection and treatment improves outcomes, but this is hampered by continued disagreement and inconsistency regarding many aspects of its diagnosis. Methods:  The Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention (DALI) research programme aims to promote pan-European standards in the detection and diagnosis of gestational diabetes and to develop effective preventive interventions. To provide an overview of the context within which the programme will be conducted and its findings interpreted, systematic searching and narrative synthesis have been used to identify and review the best available European evidence relating to the prevalence of gestational diabetes, current screening practices and barriers to screening. Results:  Prevalence is most often reported as 2-6% of pregnancies. Prevalence may be lower towards the Northern Atlantic seaboard of Europe and higher in the Southern Mediterranean seaboard. Screening practice and policy is inconsistent across Europe, hampered by lack of consensus on testing methods, diagnostic glycaemic thresholds and the value of routine screening. Poor clinician awareness of gestational diabetes, its diagnosis and local clinical guidelines further undermine detection of gestational diabetes. Conclusions:  Europe-wide agreement on screening approaches and diagnostic standards for gestational diabetes could lead to better detection and treatment, improved outcomes for women and children and a strengthened evidence base. There is an urgent need for well-designed research that can inform decisions on best practice in gestational diabetes mellitus screening and diagnosis. © 2011 The Authors. Diabetic Medicine© 2011 Diabetes UK.

  2. From Dominators to be Brothers: a dialogue of ecotheologie with J. Riechmann about the Animal Liberation

    Directory of Open Access Journals (Sweden)

    Afonso Tadeu Murad

    2016-12-01

    Full Text Available Jorge Riechmann is the author of extensive work devoted to philosophical reflection on ecology and sustainability. Among his significant works, we choose "Todos los animales somos hermanos" (2005. We will present an overview of the author's thinking about the relationship of humans with other animals, especially mammals. Riechmann addresses hot topics such as physio-biological-social continuous process of evolution and uniqueness of the human; the reasons to include the higher animals in the human moral community, and ethical and legal reasons of animal rights. It must be overcome speciesism, which considers only the animals as mere instruments. Although animals are not people, not moral agents, have intrinsic value. Because they feel pain and pleasure, and have a purpose for living, they deserve moral respect. They are "almost people" and have rights granted and recognized by humans. Next, we will do an exercise of ecotheology interlocution with Jorge Riechmann. We will take as reference the Encyclical Laudato Si and the work of Susin and Zampieri, Ethics and Theology of Animal Liberation.

  3. Kaks kirja vennale = Two Letters from Vincent van Gogh to his brother / Vincent van Gogh

    Index Scriptorium Estoniae

    Gogh, Vincent van, 1853-1890

    2008-01-01

    Kunstnik Vincent van Goghi kaks kirja oma vennale Theole. Tõlge vene keelest ja kommentaar Mehis Heinsaarelt. Ingliskeelsed kirjad raamatust "The Complete Letters of Vincent van Gogh", Thames and Hudson, 1979

  4. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Lalor, Joan G

    2012-09-01

    Several authors have suggested that computer skills should be taught within the undergraduate curriculum. In this paper, the focus is mainly on the results of an examination of midwifery students\\' search strategy in response to a specific question undertaken before and after training session in the first, second and third years of the undergraduate programme.

  5. When Your Brother or Sister Has Cancer: A Guide for Teens

    Science.gov (United States)

    ... for you. It’s okay to talk about how hard it is and even cry together. ➜ Knowledge is power. It can help to learn more about cancer ... ... Others for Help You and your family may need support from others. It can be hard to ask. Yet most of the time people ...

  6. Driver’s Big Brother: How Smartphones Can Increase Driver’s Awareness

    Directory of Open Access Journals (Sweden)

    Ashraf Khalil

    2012-10-01

    Full Text Available Using mobile devices while driving has been widely shown to pose serious safety risk. Various approaches aim at mitigating the risk of mobile devices while driving. Some initiatives have focused on increasing drivers’ awareness of such potential risk. Along the same vein, we present a model, and its implementation, for assessing the degree of distraction that drivers experience while using phones during driving. Based on data collected during each driving session, the application gives statistics, such as keypad interaction, number and length of phone calls and the driving speed, to the driver. This should increase the awareness of drivers by helping them understand how much distraction they got involved with during driving and how much hazardous they can be to themselves and to others. Our experiments with drivers demonstrated the potential of the application at highlighting risky behavior, promoting awareness and motivating better driving.

  7. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Elmusharaf, Khalifa

    2015-09-01

    Universal health access will not be achieved unless women are cared for in their own communities and are empowered to take decisions about their own health in a supportive environment. This will only be achieved by community-based demand side interventions for maternal health access. In this review article, we highlight three common strategies to increase demand-side barriers to maternal healthcare access and identify the main challenges that still need to be addressed for these strategies to be effective.

  8. Figures from the air: the mediatised verbal performances of Laurie Anderson at Warner Brothers

    OpenAIRE

    Hunninghausen, Carlos Guilherme

    2002-01-01

    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras/Inglês e Literatura Correspondente. Esta pesquisa surgiu da observação de que no início deste novo século performances que circulam na mídia parecem Ter adquirido não somente mais prestígio cultural (tendo retirado do teatro muitos dos seus privilégios) como também maior impacto na economia de símbolos culturais que funciona no presente (Auslander) e examina uma...

  9. A designated centre for people with disabilities, operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Rock, Kathy

    2010-01-01

    ABSTRACT: INTRODUCTION: Hypercalcaemic hyperparathyroid crisis is a rare but life-threatening complication of primary hyperparathyroidism. Parathyroid carcinoma is a rare malignancy with an incidence of 0.5% to 4% of all reported cases of primary hyperparathyroidism. CASE PRESENTATION: We report the case of a 60-year-old Caucasian man with hypercalcaemic hyperparathyroid crisis associated with parathyroid carcinoma. He presented with a classic hypercalcaemic syndrome and his serum calcium and parathyroid hormone levels were at 4.65 mmol\\/L and 1743 ng\\/L, respectively. He initially presented with a two-week history of weakness and lethargy and a one-week history of vomiting, polyuria and polydipsia. An emergency left thyroid lobectomy and left lower parathyroidectomy were performed. There was a prompt decrease in his parathyroid hormone level immediately after surgery. Histology revealed that our patient had a 4-cm parathyroid carcinoma. CONCLUSION: In patients with parathyroid carcinoma, the optimal surgical treatment is en bloc resection with ipsilateral thyroid lobectomy and removal of any enlarged or abnormal lymph nodes. Surgery is the only curative treatment. In our patient, prompt surgical intervention proved successful. At six months the patient is well with no evidence of disease recurrence. This case highlights the importance of considering a hyperparathyroid storm in the context of a parathyroid carcinoma. Parathyroid carcinoma is a rare entity and our knowledge is mainly derived from case reports and retrospective studies. This case report increases awareness of this serious and life-threatening complication. This report also illustrates how prompt and appropriate management provides the best outcome for the patient.

  10. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Cornally, Nicola

    2015-11-01

    The \\'Let Me Decide\\' Advance Care Planning (LMD-ACP) programme offers a structured approach to End-of-Life (EoL) care planning in long-term care for residents with and without capacity to complete an advance care directive\\/plan. The programme was implemented in three homes in the South of Ireland, with a view to improving quality of care at end of life. This paper will present an evaluation of the systematic implementation of the LMD-ACP programme in the homes.

  11. Two brothers that don't look very similar; Zwei ungleiche Brueder

    Energy Technology Data Exchange (ETDEWEB)

    Jantzen, Markus

    2009-01-15

    At first glance, the Tesla Roadster and the Elektro-Smart seem to have nothing in common, apart from the fact that they are both electric vehicles. However, the comparison is not as foolish as it seems. (orig.)

  12. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    O'Reilly, Ken

    2015-07-10

    There is a broad literature suggesting that cognitive difficulties are associated with violence across a variety of groups. Although neurocognitive and social cognitive deficits are core features of schizophrenia, evidence of a relationship between cognitive impairments and violence within this patient population has been mixed.

  13. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Davoren, Mary

    2015-01-01

    Patients admitted to a secure forensic hospital are at risk of a long hospital stay. Forensic hospital beds are a scarce and expensive resource and ability to identify the factors predicting length of stay at time of admission would be beneficial. The DUNDRUM-1 triage security scale and DUNDRUM-2 triage urgency scale are designed to assess need for therapeutic security and urgency of that need while the HCR-20 predicts risk of violence. We hypothesized that items on the DUNDRUM-1 and DUNDRUM-2 scales, rated at the time of pre-admission assessment, would predict length of stay in a medium secure forensic hospital setting.

  14. Brothers or Rivals? Iran and the Shi’a of Iraq

    Science.gov (United States)

    2006-06-01

    369. 461 Juan Cole, “Iraq: All Together Against the Occupation,” Le Monde Diplomatique , May 2004, available at http://mondediplo.com/2004/05... Monde Diplomatique , May 2004. http://mondediplo.com/2004/05/03iraqinationalism. Accessed 12 June 2006. ______. “The Iraqi Shiites: On the History...06. http://www.juancole.com/2006_05_01_juancole_archive.html. Accessed 12 June 2006. _____. “Iraq: All Together Against the Occupation,” Le

  15. Band of Brothers - Warrior Ethos, Unit Effectiveness and the Role of Initial Entry Training

    National Research Council Canada - National Science Library

    Sando, Donald

    2004-01-01

    .... Integral to continued professionalism of the Army is developing cultural attitudes beliefs and behaviors of a Warrior Ethos the culture of disciplined initiative teamwork determination sacrifice...

  16. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Galway

    LENUS (Irish Health Repository)

    Shore, Anna C

    2012-10-01

    One hundred seventy-five isolates representative of methicillin-resistant Staphylococcus aureus (MRSA) clones that predominated in Irish hospitals between 1971 and 2004 and that previously underwent multilocus sequence typing (MLST) and staphylococcal cassette chromosome mec (SCCmec) typing were characterized by spa typing (175 isolates) and DNA microarray profiling (107 isolates). The isolates belonged to 26 sequence type (ST)-SCCmec types and subtypes and 35 spa types. The array assigned all isolates to the correct MLST clonal complex (CC), and 94% (100\\/107) were assigned an ST, with 98% (98\\/100) correlating with MLST. The array assigned all isolates to the correct SCCmec type, but subtyping of only some SCCmec elements was possible. Additional SCCmec\\/SCC genes or DNA sequence variation not detected by SCCmec typing was detected by array profiling, including the SCC-fusidic acid resistance determinant Q6GD50\\/fusC. Novel SCCmec\\/SCC composite islands (CIs) were detected among CC8 isolates and comprised SCCmec IIA-IIE, IVE, IVF, or IVg and a ccrAB4-SCC element with 99% DNA sequence identity to SCC(M1) from ST8\\/t024-MRSA, SCCmec VIII, and SCC-CI in Staphylococcus epidermidis. The array showed that the majority of isolates harbored one or more superantigen (94%; 100\\/107) and immune evasion cluster (91%; 97\\/107) genes. Apart from fusidic acid and trimethoprim resistance, the correlation between isolate antimicrobial resistance phenotype and the presence of specific resistance genes was ≥97%. Array profiling allowed high-throughput, accurate assignment of MRSA to CCs\\/STs and SCCmec types and provided further evidence of the diversity of SCCmec\\/SCC. In most cases, array profiling can accurately predict the resistance phenotype of an isolate.

  17. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Clare

    LENUS (Irish Health Repository)

    Kennedy, Harry G

    2011-09-01

    This series of rating \\'ladders\\' is intended to allow a quantitative and qualitative analysis of the use of restrictive and intrusive interventions as part of the therapeutic management of violence and aggression in psychiatric hospital settings. This is an evolving handbook. The ladders are currently organised to facilitate a behavioural analysis. Context, antecedents, behaviour, interventions, consequences are conceptualised as a series of events organised in temporal sequence so that causes, interactions and effects can be considered. The complexity of analysis possible is limited by the statistical power of the numbers of cases and events available. \\r\

  18. Sibling support : The exchange of help among brothers and sisters in the Netherlands

    NARCIS (Netherlands)

    Voorpostel, M.B.J.

    2007-01-01

    The bond with a sibling is potentially the longest lasting of all personal relationships. Siblings play a significant part in each other's lives over the entire life course. They are drawn together because they share a genetic, family, social class and historic background, but they are also

  19. Siblings’ experiences of having a brother or sister with an eating disorder: a qualitative exploration

    OpenAIRE

    Varnell, Catherine Jessica

    2014-01-01

    Background: Family members of people with eating disorders are often involved in caregiving. To better understand the impact on them, outcomes such as burden, distress, and less frequently quality of life (QoL) are taken into consideration. Despite advancements in the knowledge base surrounding the experiences of adult and parental caregivers of individuals with eating disorders, particularly Anorexia Nervosa, there is a scarcity of qualitative exploration from the sibling pers...

  20. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    Mokoka, Matshediso C

    2017-06-15

    Many patients with asthma remain poorly controlled despite the use of inhaled corticosteroids and long-acting beta agonists. Poor control may arise from inadequate adherence, incorrect inhaler technique or because the condition is refractory. Without having an objective assessment of adherence, clinicians may inadvertently add extra medication instead of addressing adherence. This study aims to assess if incorporating objectively recorded adherence from the Inhaler Compliance Assessment (INCA) device and lung function into clinical decision making provides more cost-effective prescribing and improves outcomes.

  1. First-person shooter games as a way of connecting to people: "brothers in blood".

    Science.gov (United States)

    Frostling-Henningsson, Maria

    2009-10-01

    This work seeks to understand young adults' motives for online gaming and extends previous research concerning social interaction in virtual contexts. The focus of the study is on Counter-Strike and World of Warcraft. Drawing on Baudrillard's concept of simulacra, an analysis of young gamers' motivation for gaming is carried out. The empirical data was generated employing a mix of qualitative methods such as researcher introspection, observation, and interviews with young adults in two different online gaming centers in Stockholm during 2006 and 2007. The results show that online gaming is foremost motivated by social reasons providing the gamers with a possibility of cooperation and communication. Some of the gamers in the study were motivated by escapism. Online gaming also provides gamers with an experience in which "flow" can be obtained and serves as a "hallucination of the real," making it possible to do things and try out behaviors that would be impossible to do or try in real life. The gamers felt that online gaming gave them more experiences than real life could provide. For research purposes, this work provides a better understanding of the motivational aspects for gamers.

  2. 'How we learned to kill our brother'?: memory, morality and reconciliation in Peru

    Directory of Open Access Journals (Sweden)

    2000-01-01

    Full Text Available “COMMENT AVONS-NOUS APPRIS A TUER NOS FRERES ?” : MEMOIRE, MORALE ET RECONCILIATION AU PEROU. Dans cet article nous nous demandons comment certains paysans d’Ayacucho (Pérou analysent à la fois la violence politique qui a façonné leur vie quotidienne depuis 1980 et l’ordre de tuer qui a pris forme dans le contexte du conflit armé entre Sentier Lumineux, les Forces Armées Péruviennes et les rondes paysannes. Depuis 1995, nous conduisons à cet effet une recherche anthropologique dans diverses communautés du département d’Ayacucho. Nous cherchons ici à voir comment le contexte de guerre structure la vie morale en défiant les règles élémentaires du comportement humain et le sens même de la vie en communauté. Nous avons recours à une approche généalogique pour analyser les origines des interprétations morales qui surgissent dans des contextes locaux spécifiques. Aussi bien dans le processus de militarisation et de démilitarisation de la vie quotidienne, les cadres moraux qui transparaissent à travers les récits des paysans s’avèrent être un mélange synchrétique de christianisme militant, de thèmes psycho-culturels et de l’appropriation de discours extra-locaux. “¿CÓMO APRENDIMOS A MATAR A NUESTROS HERMANOS?”: MEMORIA, MORALIDAD Y RECONCILIACIÓN EN EL PERÚ. En este artículo, exploramos cómo los campesinos en Ayacucho (Perú entienden tanto la violencia política que ha moldeado la vida cotidiana desde 1980, como el mandato de matar que surgió dentro del contexto del conflicto armado entre Sendero Luminoso, las Fuerzas Armadas Peruanas, y las rondas campesinas. Hemos estado llevando a cabo una investigación antropológica desde 1995 en varias comunidades en el departamento de Ayacucho. Pretendemos explorar cómo el contexto de guerra moldea la vida moral, desafiando concepciones de la conducta humana aceptable y el sentido mismo de vivir en una comunidad humana. Utilizamos un acercamiento genealógico para analizar los orígenes de interpretaciones morales que surgen dentro de contextos locales específicos. De hecho, los marcos morales que los campesinos recuentan, sincretizan elementos de un cristianismo militante, temas psicoculturales y la apropiación de discursos extralocales, tanto en el proceso de militarización como en el proceso de desmilitarizar la vida cotidiana. In this article we explore how campesinos in Ayacucho (Peru, understand both the political violence that has contoured daily life sine 1980 as well as the mandate to kill that arose within the context of the armed conflict between the Shining Path guerrilla, the Peruvian Armed Forces and the peasant civil defense patrols. Since 1995 we had conducted anthropological research in various rural communities in Ayacucho. We investigated how war shapes moral life, challenging concepts of acceptable human conduct and the very sense of what it means to live in a human community. We utilized a genealogical approach to analyze the origins of moral interpretations that are forged in specific contexts. Indeed, the moral frameworks that villagers recount syncretize elements of militant Christianity, psychocultural themes, and the appropriation of extra-local discourses in the process of both militarizing and demilitarizing daily life.

  3. Modifiable environmental influences on body mass index shared by young adult brothers

    DEFF Research Database (Denmark)

    Rokholm, B; Silventoinen, K; Tynelius, P

    2013-01-01

    Twin and adoption studies suggest that family environment has little, if any, influence on body mass index (BMI) in adulthood. We investigated the hypothesis that the differences in the years of birth between siblings influence their similarity in BMI at comparable ages, which would give evidence...

  4. "Brother Where Art Thou?" African American Male Instructors' Perceptions of the Counselor Education Profession

    Science.gov (United States)

    Brooks, Michael; Steen, Sam

    2010-01-01

    The purpose of this study was to investigate the perceptions of African American male counselor educators regarding the limited number of African American male faculty members in counselor education. Implications and suggestions on how universities can recruit and retain African American male faculty members are provided.

  5. Power in Play: A Foucauldian Reading of A.O. Soyinka's "The Trials of Brother Jero"

    Science.gov (United States)

    Davoodifar, Mahboobeh; Asl, Moussa Pourya

    2015-01-01

    This work utilizes Foucault's articulations on the power strategies of our contemporary society. To him the subject's constitution is never a purely passive effect of power on the subject but requires the subject's own activity. This necessitates the existence of a dynamic, mutually affecting relationship, implying that one can be both dominated…

  6. Help a Brother Out: A Case Study in Multinational Intelligence Sharing, NATO SOF

    Science.gov (United States)

    2011-12-01

    timely 106 NSHQ COS briefing, October 20, 2010, and Alan Dron , “Special Network—Alliance Aims to Improve...BICES Communications & Information Systems Strategy, August 2011, 3, and Dron , “Special Network—Alliance Aims to Improve Cooperation among Special...and the Intelligence System.” International Journal of Intelligence and Counterintelligence 8, no. 4 (2005): 575–592. Dron , Alan. “Special Network

  7. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Casey, Jillian P

    2015-01-01

    Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder characterised by abnormal ciliary motion and impaired mucociliary clearance, leading to recurrent respiratory infections, sinusitis, otitis media and male infertility. Some patients also have laterality defects. We recently reported the identification of three disease-causing PCD genes in the Irish Traveller population; RSPH4A, DYX1C1 and CCNO. We have since assessed an additional Irish Traveller family with a complex phenotype involving PCD who did not have any of the previously identified PCD mutations.

  8. Rac1 and Rac3 in cell morphology and adhesion : brothers and foes

    NARCIS (Netherlands)

    Hajdo-Milašinović, A.

    2010-01-01

    Ondanks een hoge mate van homologie verschillen de kleine Rho GTPases Rac1 en Rac3 wezenlijk in de functie die ze uitoefenen. De beschreven verschillen in effecten op cell-matrix adhesie berust op het feit dat Rac1 en Rac3 onafhankelijk van elkaar en op een andere manier aan het multifunctionele

  9. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Prasad, Babu R

    2012-01-20

    Abstract Background The inherent toxicity of unmodified Quantum Dots (QDs) is a major hindrance to their use in biological applications. To make them more potent as neuroprosthetic and neurotherapeutic agents, thioglycolic acid (TGA) capped CdTe QDs, were coated with a gelatine layer and investigated in this study with differentiated pheochromocytoma 12 (PC12) cells. The QD - cell interactions were investigated after incubation periods of up to 17 days by MTT and APOTOX-Glo Triplex assays along with using confocal microscopy. Results Long term exposure (up to 17 days) to gelatinated TGA-capped CdTe QDs of PC12 cells in the course of differentiation and after neurites were grown resulted in dramatically reduced cytotoxicity compared to non-gelatinated TGA-capped CdTe QDs. Conclusion The toxicity mechanism of QDs was identified as caspase-mediated apoptosis as a result of cadmium leaking from the core of QDs. It was therefore concluded that the gelatine capping on the surface of QDs acts as a barrier towards the leaking of toxic ions from the core QDs in the long term (up to 17 days).

  10. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Tipperary

    LENUS (Irish Health Repository)

    Nicholl, Honor

    2014-04-01

    In 2010\\/12 an innovative children\\'s palliative care interprofessional educational project funded by the Irish Hospice Foundation was undertaken in a University faculty (Trinity College Dublin). This initiative responded to international educational recommendations to meet the palliative care needs of children. The project involved the development and delivery of 3 standalone modules at Master\\'s level and a substantive research evaluation of the project to examine stakeholders and students perspectives to provide an insight into their experiences and to gather data for future developments. The research evaluation was conducted in two parts, part one sought students\\' evaluation and part two sought stakeholders\\

  11. "The Two Brothers": Reconciling Perceptual-Cognitive and Statistical Models of Musical Evolution.

    Science.gov (United States)

    Jan, Steven

    2018-01-01

    While the "units, events and dynamics" of memetic evolution have been abstractly theorized (Lynch, 1998), they have not been applied systematically to real corpora in music. Some researchers, convinced of the validity of cultural evolution in more than the metaphorical sense adopted by much musicology, but perhaps skeptical of some or all of the claims of memetics, have attempted statistically based corpus-analysis techniques of music drawn from molecular biology, and these have offered strong evidence in favor of system-level change over time (Savage, 2017). This article argues that such statistical approaches, while illuminating, ignore the psychological realities of music-information grouping, the transmission of such groups with varying degrees of fidelity, their selection according to relative perceptual-cognitive salience, and the power of this Darwinian process to drive the systemic changes (such as the development over time of systems of tonal organization in music) that statistical methodologies measure. It asserts that a synthesis between such statistical approaches to the study of music-cultural change and the theory of memetics as applied to music (Jan, 2007), in particular the latter's perceptual-cognitive elements, would harness the strengths of each approach and deepen understanding of cultural evolution in music.

  12. From My Own Brother in My Own Home: Children's Experiences and Perceptions Following Alleged Sibling Incest.

    Science.gov (United States)

    Katz, Carmit; Hamama, Liat

    2015-08-30

    Sibling incest is an understudied field despite its high prevalence rates. The current study was designed to characterize the way children describe their experiences and perceptions following alleged sibling incest. The sample consisted of 20 forensic investigations with children who were referred to forensic investigation following suspected sibling incest. The age range of the children was between 6 and 12 years old, including 17 girls and three boys. Thematic analysis was conducted on all the interviews and the children's perceptions greatly echoed the ecological framework while they elaborated on three levels: family level, in which children discussed the context of the abuse and the disclosure; sibling level, in which children discussed their siblings' behaviors and the grooming process; and the child level, in which the children discussed their own behavior during the abuse. The discussion highlights the relevance of the ecological framework to the study's results and stresses the complexity of this phenomenon and the challenges it raises for practitioners in various contexts-child protective, forensic, and clinical. © The Author(s) 2015.

  13. Effects of Older Brother-Younger Sister Incest: A Study of the Dynamics of 17 Cases.

    Science.gov (United States)

    Laviola, Marisa

    1992-01-01

    This study of 17 cases of incest between siblings found the women commonly experienced mistrust of men and women, chronic low or negative self-esteem, sexual response difficulties, and intrusive thoughts of the incest. Individual therapy, talking with supportive family and friends, and validating themselves as victims were seen as helpful.…

  14. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Clare

    LENUS (Irish Health Repository)

    Surgenor, Paul Wg

    2015-01-01

    While most crisis intervention models adhere to a generalised theoretical framework, the lack of clarity around how these should be enacted has resulted in a proliferation of models, most of which have little to no empirical support. The primary aim of this research was to propose a suicide intervention model that would resolve the client\\'s suicidal crisis by decreasing their suicidal ideation and improve their outlook through enhancing a range of protective factors. The secondary aim was to assess the impact of this model on negative and positive outlook.

  15. "A Message for My Brother": The Vietnam Veterans' Memorial as Rhetorical Situation.

    Science.gov (United States)

    Carlson, A. Cheree; Hocking, John E.

    An examination of letters left at the Vietnam Veteran's Memorial in Washington, D.C. between November, 1984 and April, 1986 revealed that the memorial serves as a rhetorical situation that urges its visitors to eloquence. The memorial is an excellent proving ground for situational theory because the interaction of site and perception is vital to…

  16. A designated centre for people with disabilities operated by Brothers of Charity Services Clare, Clare

    LENUS (Irish Health Repository)

    O'Shea, E.

    2006-11-20

    Several instruments have been used to measure absorbed radiation dose under non-electronic equilibrium conditions, such as in the build-up region or near the interface between two different media, including the surface. Many of these detectors are discussed in this paper. A common method of measuring the absorbed dose distribution and electron contamination in the build-up region of high-energy beams for radiation therapy is by means of parallel-plate ionisation chambers. Thermoluminescent dosimeters (TLDs), diodes and radiographic film have also been used to obtain surface dose measurements. The diamond detector was used recently by the author in an investigation on the effects of beam-modifying devices on skin dose and it is also described in this report

  17. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Tipperary

    LENUS (Irish Health Repository)

    Smart, Keith M

    2012-08-01

    As a mechanisms-based classification of pain \\'nociceptive pain\\' (NP) refers to pain attributable to the activation of the peripheral receptive terminals of primary afferent neurones in response to noxious chemical, mechanical or thermal stimuli. The symptoms and signs associated with clinical classifications of NP have not been extensively studied. The purpose of this study was to identify symptoms and signs associated with a clinical classification of NP in patients with low back (± leg) pain. Using a cross-sectional, between-subjects design; four hundred and sixty-four patients with low back (± leg) pain were assessed using a standardised assessment protocol after which their pain was assigned a mechanisms-based classification based on experienced clinical judgement. Clinicians then completed a clinical criteria checklist indicating the presence\\/absence of various symptoms and signs. A regression analysis identified a cluster of seven clinical criteria predictive of NP, including: \\'Pain localised to the area of injury\\/dysfunction\\

  18. Acid Brothers: Henry Beecher, Timothy Leary, and the psychedelic of the century.

    Science.gov (United States)

    Moreno, Jonathan D

    2016-01-01

    Henry Knowles Beecher, an icon of human research ethics, and Timothy Francis Leary, a guru of the counterculture, are bound together in history by the synthetic hallucinogen lysergic acid diethylamide (LSD). Both were associated with Harvard University during a critical period in their careers and of drastic social change. To all appearances the first was a paragon of the establishment and a constructive if complex hero, the second a rebel and a criminal, a rogue and a scoundrel. Although there is no evidence they ever met, Beecher's indirect struggle with Leary over control of the 20th century's most celebrated psychedelic was at the very heart of his views about the legitimate, responsible investigator. That struggle also proves to be a revealing bellwether of the increasingly formalized scrutiny of human experiments that was then taking shape.

  19. 77 FR 24554 - Culturally Significant Objects Imported for Exhibition; Determinations: “Quay Brothers: On...

    Science.gov (United States)

    2012-04-24

    ... display of the exhibit objects at The Museum of Modern Art, New York, NY, from on or about August 12, 2012... temporary exhibition within the United States, are of cultural significance. The objects are imported...

  20. 75 FR 12154 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

    Science.gov (United States)

    2010-03-15

    ...)2890-462469; fax +44(0)2890- 468444; e-mail [email protected] ; Internet http... docket on the Internet at http://www.regulations.gov ; or in person at the Docket Operations office... 2005/CPRO, www.easa.eu.int/home/cert_policy_statements_en.html ) that also included the EASA...

  1. A designated centre for people with disabilities operated by Brothers of Charity Services Limerick, Limerick

    LENUS (Irish Health Repository)

    Corcoran, Shane

    2012-07-18

    AbstractA 54 year old lady presented for routine excision of a scalp lesion thought clinically to represent a sebaceous cyst of the right occiput. 4 years earlier she underwent total abdominal hysterectomy and right salpingo-oophorectomy for 3 large uterine fibroids. Histo-pathological examination of the hysterectomy specimen revealed an incidental low-grade leiomyosarcoma. Staging imaging was negative for metastatic disease. She made an uneventful recovery and was treated further by adjuvant pelvic radiotherapy.She noticed an uncomfortable and unsightly cystic swelling on her occiput four years after hysterectomy and was referred for routine excision of what was believed to be a benign lesion. The lesion was excised and sent for histopathological examination. Microscopic analysis including immuno-histochemistry demonstrated an ER and PR positive metastatic deposit of leiomyosarcoma. The margins of excision were histologically clear of disease.At Multi-Disciplinary Team (MDT) discussion a diagnosis of metastatic scalp deposit from previous uterine leiomyosarcoma was made. Re-staging CT brain, thorax, abdomen and pelvis and MRI brain were negative for local recurrence or distant metastases. She is currently undergoing radiotherapy to the scalp and surrounding tissues and will be followed up closely by the involved teams.To the best of our knowledge, this is the first case described in the worldwide literature of isolated cutaneous metastasis to the scalp of uterine leiomyosarcoma without evidence of disseminated disease at other sites.Virtual slidesThe virtual slide(s) for this article can be found here: http:\\/\\/www.diagnosticpathology.diagnomx.eu\\/vs\\/1311834987345566.

  2. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Daly, Louise

    2015-03-01

    This article reports on an evaluation of four family support programmes in Ireland for families of people with a physical or an intellectual disability or autism. The focus of the evaluation, which took place within a year of the programmes\\' completion, was on establishing whether the programmes had an impact on families\\' capacity to effectively support their family member.

  3. Who Will be My Brother's Keeper--My First Visit to Haiti

    Science.gov (United States)

    Tinker Sachs, Gertrude

    2013-01-01

    In this article, the author describes her preparations for the Teaching English to Speakers of Other Languages (TESOL) professional presentations in Haiti. As a cultural worker, (after Paulo Freire), she was very conscious of the need for care in working with "the Other" especially when the Other is known only from second hand…

  4. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon, Roscommon

    LENUS (Irish Health Repository)

    Murphy, Andrew W

    2005-07-29

    BACKGROUND: The aim of the SPHERE study is to design, implement and evaluate tailored practice and personal care plans to improve the process of care and objective clinical outcomes for patients with established coronary heart disease (CHD) in general practice across two different health systems on the island of Ireland. CHD is a common cause of death and a significant cause of morbidity in Ireland. Secondary prevention has been recommended as a key strategy for reducing levels of CHD mortality and general practice has been highlighted as an ideal setting for secondary prevention initiatives. Current indications suggest that there is considerable room for improvement in the provision of secondary prevention for patients with established heart disease on the island of Ireland. The review literature recommends structured programmes with continued support and follow-up of patients; the provision of training, tailored to practice needs of access to evidence of effectiveness of secondary prevention; structured recall programmes that also take account of individual practice needs; and patient-centred consultations accompanied by attention to disease management guidelines. METHODS: SPHERE is a cluster randomised controlled trial, with practice-level randomisation to intervention and control groups, recruiting 960 patients from 48 practices in three study centres (Belfast, Dublin and Galway). Primary outcomes are blood pressure, total cholesterol, physical and mental health status (SF-12) and hospital re-admissions. The intervention takes place over two years and data is collected at baseline, one-year and two-year follow-up. Data is obtained from medical charts, consultations with practitioners, and patient postal questionnaires. The SPHERE intervention involves the implementation of a structured systematic programme of care for patients with CHD attending general practice. It is a multi-faceted intervention that has been developed to respond to barriers and solutions to optimal secondary prevention identified in preliminary qualitative research with practitioners and patients. General practitioners and practice nurses attend training sessions in facilitating behaviour change and medication prescribing guidelines for secondary prevention of CHD. Patients are invited to attend regular four-monthly consultations over two years, during which targets and goals for secondary prevention are set and reviewed. The analysis will be strengthened by economic, policy and qualitative components.

  5. A designated centre for people with disabilities operated by Brothers of Charity Services Clare

    LENUS (Irish Health Repository)

    O’Leary, B

    2016-02-01

    Vaginal bleeding is a common event in early pregnancy, with 20-40% of pregnancies affected. Prompt diagnosis and management of bleeding is important, both to reduce morbidity and to avoid excessive emotional distress. This was a prospective study of an educational programme aimed at Obstetrics and Gynaecology BST trainees in the National Maternity Hospital, Dublin. The educational programme consisted of didactic lectures, and simulation and practical sessions. A questionnaire reviewing early pregnancy complications was used to assess participant knowledge. Six trainees participated in the programme, with five (83%) answering the questionnaire. The pre-education questionnaire showed a generally poor level of knowledge of early pregnancy complications with 8\\/50 (16%) questions answered correctly. Following the educational intervention there was a statistically significant increase in participant knowledge with 45\\/50 (90%) questions answered correctly. A significant increase in participant knowledge of early pregnancy complications followed our multifaceted educational programme. Study limitations exist, however we have shown the potential value of our educational programme.

  6. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    Bennett, Annemarie E

    2014-08-06

    Adults with an intellectual disability have poorer diets than the general adult population. The Able 2 Cook 4 Health cookery course aims to improve the diets of adults with mild to moderate intellectual disability. This study aims to evaluate the course by obtaining the views of course participants and the views of managers hosting the course. Thirty course participants took part in focus groups. Five managers hosting the course participated in a semi-structured interview. Positive features of the course included the group cooking, social interaction and course instructors. Collaboration between centres hosting the course and participants\\' home environment is needed to help transfer the skills learned to all home settings. The Able 2 Cook 4 Health cookery course provided participants with an important social outlet to learn essential occupational skills. These findings could particularly influence the diets of adults with an intellectual disability moving into independent living.

  7. A designated centre for people with disabilities operated by Brothers of Charity Services Galway, Galway

    LENUS (Irish Health Repository)

    Harrington, Deirdre M.

    2011-10-28

    Abstract Background Adolescent females have been highlighted as a particularly sedentary population and the possible negative effects of a sedentary lifestyle are being uncovered. However, much of the past sedentary research is based on self-report or uses indirect methods to quantity sedentary time. Total time spent sedentary and the possible intricate sedentary patterns of adolescent females have not been described using objective and direct measure of body inclination. The objectives of this article are to examine the sedentary levels and patterns of a group of adolescent females using the ActivPAL™ and to highlight possible differences in sedentary levels and patterns across the week and within the school day. A full methodological description of how the data was analyzed is also presented. Methods One hundred and eleven adolescent females, age 15-18 yrs, were recruited from urban and rural areas in the Republic of Ireland. Participants wore an ActivPAL physical activity monitor for a 7.5 day period. The ActivPAL directly reports total time spent sitting\\/lying every 15 seconds and accumulation (frequency and duration) of sedentary activity was examined using a customized MATLAB ® computer software programme. Results While no significant difference was found in the total time spent sitting\\/lying over the full 24 hour day between weekday and weekend day (18.8 vs. 18.9 hours; p = .911), significantly more sedentary bouts of 1 to 5 minutes and 21 to 40 minutes in duration were accumulated on weekdays compared to weekend days (p < .001). The mean length of each sedentary bout was also longer (9.8 vs. 8.8 minutes; p < .001). When school hours (9 am-3 pm) and after school hours (4 pm-10 pm) were compared, there was no difference in total time spent sedentary (3.9 hours; p = .796) but the pattern of accumulation of the sedentary time differed. There were a greater number of bouts of > 20 minutes duration during school hours than after school hours (4.7 vs. 3.5 bouts; p < .001) while after school time consisted of shorter bouts < 20 minutes. Conclusions School is highlighted as a particularly sedentary setting for adolescent females. Interventions to decrease sedentary time at school and the use of wearable devices which distinguish posture should be encouraged when examining sedentary patterns and behaviors in this population.

  8. Brothers, Sisters and Fictive Kin: Communication about Sex among Urban Black Siblings

    Science.gov (United States)

    Wallace, Scyatta A.; Hooper, Lisa M.; Persad, Malini

    2014-01-01

    Siblings have been shown to influence youth substance use and violent behavior. However, limited research has examined sibling-influences on sexual activity, particularly among urban Black youth. The current qualitative research was an exploratory study to describe discussions among siblings about sex and sexual health. Individual interviews were…

  9. Ellis-van Creveld Syndrome: A Case Report of Two Brothers

    OpenAIRE

    Tibin K Baby; Rekha Krishna Pillai; PR Bindhu; Priya Thomas

    2016-01-01

    Ellis-van Creveld (EVC) syndrome is a rare genetic disorder with autosomal recessive transmission, clinically presenting as bilateral postaxial polydactyly, chondrodysplasia of long bones resulting in acromesomelic dwarfism and ectodermal dysplasia. Mutation in EVC1 and EVC2 gene located in a head to head configuration on chromosome 4p16 has been associ - ated with this syndrome. In Amish community of Pennsylvania, EVC prevalence rate is 1/5,000 and, in non-A...

  10. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon

    LENUS (Irish Health Repository)

    Carew, Rosemarie M.

    2010-07-06

    Abstract Background Male Irs2-\\/- mice develop fatal type 2 diabetes at 13-14 weeks. Defects in neuronal proliferation, pituitary development and photoreceptor cell survival manifest in Irs2-\\/- mice. We identify retarded renal growth in male and female Irs2-\\/- mice, independent of diabetes. Results Kidney size and kidney:body weight ratio were reduced by approximately 20% in Irs2-\\/- mice at postnatal day 5 and was maintained in maturity. Reduced glomerular number but similar glomerular density was detected in Irs2-\\/- kidney compared to wild-type, suggesting intact global kidney structure. Analysis of insulin signalling revealed renal-specific upregulation of PKBβ\\/Akt2, hyperphosphorylation of GSK3β and concomitant accumulation of β-catenin in Irs2-\\/- kidney. Despite this, no significant upregulation of β-catenin targets was detected. Kidney-specific increases in Yes-associated protein (YAP), a key driver of organ size were also detected in the absence of Irs2. YAP phosphorylation on its inhibitory site Ser127 was also increased, with no change in the levels of YAP-regulated genes, suggesting that overall YAP activity was not increased in Irs2-\\/- kidney. Conclusions In summary, deletion of Irs2 causes reduced kidney size early in mouse development. Compensatory mechanisms such as increased β-catenin and YAP levels failed to overcome this developmental defect. These data point to Irs2 as an important novel mediator of kidney size.

  11. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    Reid, Angela

    2011-01-01

    Substantial progress has been made in the medical management of rheumatoid arthritis (RA) over the past decade with the introduction of biologic therapies, including anti-tumour necrosis factor alpha (anti-TNFα) therapy medications. However, individuals with RA taking anti-TNFα medication continue to experience physical, psychological and functional consequences, which could potentially benefit from rehabilitation. There is evidence that therapeutic exercise should be included as an intervention for people with RA, but to date there is little evidence of the benefits of therapeutic exercise for people with RA on anti-TNFα therapy medication. A protocol for a multicentre randomised controlled three-armed study which aims to examine the effect of dynamic group exercise therapy on land or in water for people with RA taking anti-TNFα therapy medication is described.

  12. Severe protein-calorie malnutrition in two brothers due to abuse by starvation.

    Science.gov (United States)

    Barroso, Marcela Montenegro Braga; Salvador, Luiza Martins; Fagundes Neto, Ulysses

    2016-12-01

    To describe the case of two siblings with severe protein-calorie malnutrition due to abuse by starvation. The two patients were simultaneously referred from the Municipal Hospital, where they were admitted to the Pediatric Gastroenterology clinic of a university hospital for diagnostic investigation of the cause of severe malnutrition and screening tests for Celiac Disease, Cystic Fibrosis and Environmental enteropathy among others. The exams were all normal, and after detailed research on the interactions of this family, we reached the conclusion that the malnutrition was due to abuse by starvation. The children spent approximately two months in the hospital, receiving a high-protein and high-calorie diet, with significant nutritional recovery. Abuse by starvation, although rare, should always be considered of as one of the causes of child malnutrition and pediatrician should be aware of the child's development, as well as the family interactions, to prevent more severe nutritional and emotional consequences in the future. Copyright © 2016. Publicado por Elsevier Editora Ltda.

  13. Family-focused prevention with Latinos: What about sisters and brothers?

    Science.gov (United States)

    Updegraff, Kimberly A; Umaña-Taylor, Adriana J; Rodríguez De Jesús, Sue A; McHale, Susan M; Feinberg, Mark F; Kuo, Sally I-Chun

    2016-08-01

    Using a randomized, intent-to-treat design, this pilot study examined the feasibility and short-term effects of Siblings Are Special ( SIBS ) with a sample of 54 low-income Latino families (91% Mexican-origin). Participants were older (M = 10.8 years; SD = .46) and younger siblings (M = 8.4 years; SD = 1.13), and their parents (94% biological mothers), who were randomly assigned within school to the intervention (n = 28) or no-attention control (n = 26) condition. The intervention condition included 12 weekly afterschool sessions (90 min each) for sibling pairs and 3 family nights for parents and siblings (2 hr each). SIBS was designed to enhance sibling relationships via 2 primary intervention targets: (a) children’s capacities that underlie positive sibling dynamics, including relationship skills, cognitions, and shared activities; and (b) parenting of siblings, specifically, enhancing positive guidance and involvement and discouraging authoritarian control. Pre- and posttest data were gathered from siblings and parents. Recruitment and implementation data revealed high rates of attendance and completion, and high ratings of parent satisfaction with the program. Further, analyses suggested the program had positive effects of small to modest magnitude on posttest measures of sibling and parent–child relationship quality, parenting of siblings, older siblings’ emotional efficacy, and parents’ depressive symptoms and parenting stress, controlling for pretest levels of all outcomes and family background characteristics. Discussion addresses the feasibility of sibling-focused programs with low-income Latino families and makes recommendations for future research. PsycINFO Database Record (c) 2016 APA, all rights reserved

  14. A designated centre for people with disabilities operated by Brothers of Charity Services Ireland, Clare

    LENUS (Irish Health Repository)

    O'Rourke, Colm J

    2013-05-01

    Urological malignancies (cancers of the prostate, bladder, kidney and testes) account for 15% of all human cancers and more than 500,000 deaths worldwide each year. This group of malignancies is spread across multiple generations, affecting the young (testicular) through middle and old-age (kidney, prostate and bladder). Like most human cancers, urological cancers are characterized by widespread epigenetic insult, causing changes in DNA hypermethylation and histone modifications leading to silencing of tumor suppressor genes and genomic instability. The inherent stability yet dynamic plasticity of the epigenome lends itself well to therapeutic manipulation. Epigenetic changes are amongst the earliest lesions to occur during carcinogenesis and are essentially reversible (unlike mutations). For this reason, much attention has been placed over the past two decades on deriving pharmacological compounds that can specifically target and reverse such epi-mutations, either halting cancer on its developmental trajectory or reverting fully formed cancers to a more clinically manageable state. This review discusses DNA methyltransferase and histone deacetylase inhibitors that have been extensively studied in preclinical models and clinical trials for advanced and metastatic urological cancers.

  15. 76 FR 1985 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes

    Science.gov (United States)

    2011-01-12

    ... those in the MCAI to ensure the AD is clear for U.S. operators and is enforceable in a U.S. court of law..., Belfast, BT3 9DZ Northern Ireland; telephone +44(0)2890-462469; fax +44(0)2890-468444; e-mail michael...

  16. What We Learn from Our Sisters and Brothers: For Better or for Worse

    Science.gov (United States)

    Kramer, Laurie; Conger, Katherine J.

    2009-01-01

    Siblings have considerable influence on one another's development throughout childhood, yet most human development research has neglected sibling socialization. Through this volume, we aim to enhance our understanding of how siblings play formative roles in one another's social and emotional development. We examine the mechanisms by which children…

  17. A designated centre for people with disabilities operated by Brothers of Charity Services Roscommon

    LENUS (Irish Health Repository)

    2012-05-23

    AbstractBackgroundRadiotherapy (RT) and androgen-deprivation therapy (ADT) are standard treatments for advanced prostate cancer (PC). Tumor vascularization is recognized as an important physiological feature likely to impact on both RT and ADT response, and this study therefore aimed to characterize the vascular responses to RT and ADT in experimental PC.MethodsUsing mice implanted with CWR22 PC xenografts, vascular responses to RT and ADT by castration were visualized in vivo by DCE MRI, before contrast-enhancement curves were analyzed both semi-quantitatively and by pharmacokinetic modeling. Extracted image parameters were correlated to the results from ex vivo quantitative fluorescent immunohistochemical analysis (qIHC) of tumor vascularization (9 F1), perfusion (Hoechst 33342), and hypoxia (pimonidazole), performed on tissue sections made from tumors excised directly after DCE MRI.ResultsCompared to untreated (Ctrl) tumors, an improved and highly functional vascularization was detected in androgen-deprived (AD) tumors, reflected by increases in DCE MRI parameters and by increased number of vessels (VN), vessel density ( VD), and vessel area fraction ( VF) from qIHC. Although total hypoxic fractions ( HF) did not change, estimated acute hypoxia scores ( AHS) – the proportion of hypoxia staining within 50 μm from perfusion staining – were increased in AD tumors compared to in Ctrl tumors. Five to six months after ADT renewed castration-resistant (CR) tumor growth appeared with an even further enhanced tumor vascularization. Compared to the large vascular changes induced by ADT, RT induced minor vascular changes. Correlating DCE MRI and qIHC parameters unveiled the semi-quantitative parameters area under curve ( AUC) from initial time-points to strongly correlate with VD and VF, whereas estimation of vessel size ( VS) by DCE MRI required pharmacokinetic modeling. HF was not correlated to any DCE MRI parameter, however, AHS may be estimated after pharmacokinetic modeling. Interestingly, such modeling also detected tumor necrosis very strongly.ConclusionsDCE MRI reliably allows non-invasive assessment of tumors’ vascular function. The findings of increased tumor vascularization after ADT encourage further studies into whether these changes are beneficial for combined RT, or if treatment with anti-angiogenic therapy may be a strategy to improve the therapeutic efficacy of ADT in advanced PC.

  18. A designated centre for people with disabilities operated by Brothers of Charity Services Limerick, Limerick

    LENUS (Irish Health Repository)

    Fang, Fang

    2009-09-01

    Commensal lactobacilli frequently produce bile salt hydrolase (Bsh) enzymes whose roles in intestinal survival are unclear. Twenty-six Lactobacillus salivarius strains from different sources all harbored a bsh1 allele on their respective megaplasmids. This allele was related to the plasmid-borne bsh1 gene of the probiotic strain UCC118. A second locus (bsh2) was found in the chromosomes of two strains that had higher bile resistance levels. Four Bsh1-encoding allele groups were identified, defined by truncations or deletions involving a conserved residue. In vitro analyses showed that this allelic variation was correlated with widely varying bile deconjugation phenotypes. Despite very low activity of the UCC118 Bsh1 enzyme, a mutant lacking this protein had significantly lower bile resistance, both in vitro and during intestinal transit in mice. However, the overall bile resistance phenotype of this and other strains was independent of the bsh1 allele type. Analysis of the L. salivarius transcriptome upon exposure to bile and cholate identified a multiplicity of stress response proteins and putative efflux proteins that appear to broadly compensate for, or mask, the effects of allelic variation of bsh genes. Bsh enzymes with different bile-degrading kinetics, though apparently not the primary determinants of bile resistance in L. salivarius, may have additional biological importance because of varying effects upon bile as a signaling molecule in the host.

  19. A designated centre for people with disabilities operated by Brothers of Charity Services South East, Waterford

    LENUS (Irish Health Repository)

    Barnett, Julie

    2011-05-13

    Abstract Background European consumers are faced with a myriad of food related risk and benefit information and it is regularly left up to the consumer to interpret these, often conflicting, pieces of information as a coherent message. This conflict is especially apparent in times of food crises and can have major public health implications. Scientific results and risk assessments cannot always be easily communicated into simple guidelines and advice that non-scientists like the public or the media can easily understand especially when there is conflicting, uncertain or complex information about a particular food or aspects thereof. The need for improved strategies and tools for communication about food risks and benefits is therefore paramount. The FoodRisC project ("Food Risk Communication - Perceptions and communication of food risks\\/benefits across Europe: development of effective communication strategies") aims to address this issue. The FoodRisC project will examine consumer perceptions and investigate how people acquire and use information in food domains in order to develop targeted strategies for food communication across Europe. Methods\\/Design This project consists of 6 research work packages which, using qualitative and quantitative methodologies, are focused on development of a framework for investigating food risk\\/benefit issues across Europe, exploration of the role of new and traditional media in food communication and testing of the framework in order to develop evidence based communication strategies and tools. The main outcome of the FoodRisC project will be a toolkit to enable coherent communication of food risk\\/benefit messages in Europe. The toolkit will integrate theoretical models and new measurement paradigms as well as building on social marketing approaches around consumer segmentation. Use of the toolkit and guides will assist policy makers, food authorities and other end users in developing common approaches to communicating coherent messages to consumers in Europe. Discussion The FoodRisC project offers a unique approach to the investigation of food risk\\/benefit communication. The effective spread of food risk\\/benefit information will assist initiatives aimed at reducing the burden of food-related illness and disease, reducing the economic impact of food crises and ensuring that confidence in safe and nutritious food is fostered and maintained in Europe.

  20. Big Brothers: hegemonía mediática en el proceso electoral de 2006

    Directory of Open Access Journals (Sweden)

    Jorge Balderas Domínguez

    2007-01-01

    Full Text Available El presente artículo analiza la manera en que la televisión mexicana cubrió el proceso electoral de 2006. Aborda también los vínculos de las dos principales empresas con las élites hegemónicas del país, ya sean éstas económicas o políticas, dependiendo la coyuntura histórica. A su vez, intenta desarrollar un análisis crítico basado en estudios teóricos sobre la función social de los medios, particularmente, de la omnipresencia de la televisión que pareciera erigirse en el Gran Hermano (que te vigila, en una nueva especie de mundo orwelliano.

  1. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

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    O'Neill, Sinéad M

    2017-02-27

    Caesarean section (CS) rates are increasing worldwide and as a result repeat CS is common. The optimal mode of delivery in women with one previous CS is widely debated and the risks to the infant are understudied. The aim of the current study was to evaluate if women with a trial of labour after caesarean (TOLAC) had an increased odds of neonatal and infant death compared to women with an elective repeat CS (ERCS).

  2. "[This] Book of Odd Tales/Which Transform the Brothers Grimm": Teaching Anne Sexton's "Transformations"

    Science.gov (United States)

    Keely, Karen A.

    2008-01-01

    Folklorist Andrew Lang, in his Preface to his 1910 edited collection "The Lilac Fairy Book", celebrates the ongoing repetition and retelling of fairy tales, including both the cozy retelling by the family fireplace. In the century since Lang wrote these words, many authors have joined the ranks of Shakespeare and Homer in putting fairy tale…

  3. Fatherhood in eighteenth-century Holland : The Van der Muelen brothers

    NARCIS (Netherlands)

    Roberts, B

    1996-01-01

    Until recently fatherhood in the Early Modem period has been largely unknown terrain. Books of advice on the physical upbringing of children were addressed to mothers, implying that fathers were not involved in the process. However iconographic evidence presented by Simon Schama suggests that

  4. Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.

    Science.gov (United States)

    Buchberger, Alexander; Bukau, Bernd; Sommer, Thomas

    2010-10-22

    In cells, both newly synthesized and pre-existing proteins are constantly endangered by misfolding and aggregation. The accumulation of damaged proteins can perturb cellular homeostasis and provoke aging, pathological states, and even cell death. To avert these dangers, cells have developed powerful quality control strategies that counteract protein damage in a compartment-specific way. Here, we compare the protein quality control systems of the eukaryotic cytosol and the endoplasmic reticulum, focusing on the principles of damage recognition, the triage decisions between chaperone-mediated refolding and proteolytic elimination of damaged proteins, the repair of misfolded and aggregated protein species, and the mechanisms by which perturbations of protein homeostasis are sensed to induce compartment-specific stress responses. Copyright © 2010 Elsevier Inc. All rights reserved.

  5. A designated centre for people with disabilities operated by Brothers of Charity Southern Services, Cork

    LENUS (Irish Health Repository)

    2017-11-25

    Background: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the \\'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale\\' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother\\/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.

  6. Physiochemical and Phytochemical Properties of Wax Apple (Syzygium samarangense [Blume] Merrill & L. M. Perry var. Jambu Madu as Affected by Growth Regulator Application

    Directory of Open Access Journals (Sweden)

    Mohammad Moneruzzaman Khandaker

    2012-01-01

    Full Text Available This study represents the first paper of the effects of growth regulators on the physiochemical and phytochemical properties of the wax apple fruit, a widely cultivated fruit tree in southeast Asia. Net photosynthesis, sucrose phosphate synthase (SPS activity, peel color, fruit firmness, juice content, pH value, total soluble solids (TSSs, and the sugar acid ratio were all significantly increased in growth regulators (PGRs treated fruits. The application of gibberellin (GA3, naphthalene acetic acid (NAA, and 2,4-dichlorophenoxy acetic acid (2,4-D significantly reduced titratable acidity and increased total sugar and carbohydrate content compared to the control. The 50 mg/L GA3, 10 mg/L NAA, and 5 mg/L 2,4-D treatments produced the greatest increases in phenol and flavonoid content; vitamin C content was also higher for these treatments. PGR treatment significantly affected chlorophyll, anthocyanin, and carotene content and produced higher phenylalanine ammonia lyase (PAL and antioxidant activity levels. There was a positive correlation between peel color and TSS and antioxidant activity and both phenol and flavonoid content and PAL activity and anthocyanin formation. A taste panel assessment was also performed, and the highest scores were given to fruits that had been treated with GA3 or auxin. The study showed that application of 50 mg/L GA3, 10 mg/L NAA, and 5 mg/L 2,4-D once a week from bud development to fruit maturation increased the physiochemical and phytochemical properties of wax apple fruits.

  7. Rate and time of nitrogen fertilizer application on the growth, nitrogen remobilization and yield of soyabean (Glycine max(L) Merrill)

    International Nuclear Information System (INIS)

    Bebeley, J. F.; Sarkodie-Addo; Duku, S.

    2015-01-01

    Two field experiments were conducted in 2012 at the plantation Crop section of the Department of Crop and Soil Sciences, Kwame Nkrumah University of Science and Technology, to investigate the effect N availability on nodulation, nitrogen fixation, N remobilization and grain yield of soybean. The design used in both studies was a 3 x 4 factorial arranged in randomized complete block design. Each treatment was replicated three times. The factors studied were rate and time of N fertilizer application. The N rate were 0, 20, 40 and 60kg N/ha and the time of application were early vegetative and early flowering phases. Anidaso, an improved soybean variety of 110 days maturity was used. Following land preparation, seeds were planted at the beginning of the rains at a spacing of 50 x 5cm. All required cultural practices were observed. Data collected were nodule number per plant and nodule dry weight, number of pods per plant, number of seeds per pod, 100 seeds weight, total nitrogen fixed, harvest index, grain yield and remobilized N. The total nitrogen difference method was used in determining the amount of N 2 fixed by the soybean and the micro kjeldahl method was used in determining the total plant N. The results indicated that nodulation was not significantly (p>0.05) affected by N rate and time of N application. However Nitrogen fixation was significantly (p<0.05 in affected time of N application in the minor season. Harvest index was significantly affected time of N application in the major season. Grain yield was also significantly affected by time of N application in both seasons. The results indicate that if farmers would apply N fertilizer to soybean at the vegetative growth phase, there would be increase in yield. The study also demonstrate that N remobilization occurs in soybean during grain filling although rate and time of application used did not significantly (p>0.05) affect N remobilization. (au)

  8. Mejoramiento genético de la soya (Glycine max [L.] Merril para su cultivo en la altillanura colombiana: una visión conceptual prospectiva

    Directory of Open Access Journals (Sweden)

    Valencia Ruben

    2010-08-01

    Full Text Available La soya es materia prima esencial para la elaboración de concentrados
    balanceados para la alimentación animal, en particular
    para la cadena avícola y porcícola. En cuanto a su cultivo, constituye
    una alternativa de rotación en el trópico bajo. La producción
    nacional de soya cubre un bajo porcentaje de la demanda
    nacional, lo cual implica altos volúmenes de importación. En
    Colombia la producción nacional depende en su mayoría de
    la variedad Soyica P-34, la superación de cuyas limitaciones
    de producción hace necesario generar nuevas alternativas que
    ofrezcan ventajas comparativas. La Altillanura colombiana,
    caracterizada por tener suelos ácidos saturados en aluminio,
    presenta un alto potencial para la producción competitiva de
    soya. Por ello, los programas de mejoramiento genético de este
    grano deben hacer énfasis en su calidad, adaptación específica,
    tolerancia a enfermedades y alto rendimiento. En este contexto,
    el presente trabajo desarrolla una visión prospectiva de los
    principales avances en el mejoramiento genético de la soya para
    la altillanura colombiana.

  9. PERTUMBUHAN DAN HASIL TANAMAN KEDELAI PADA KONDISI CEKAMAN AIR DAN PEMBERIAN MIKOKOMPOS (Growth and Yield of Soybean (Glycine max (L) Merril) Under Water Stress Conditions and Mycocompost Application)

    OpenAIRE

    Buhaira, .; Soverda, Nerty; Lestari, Ardiyaningsih Puji; Achnopa, Yudi

    2013-01-01

    Thi research was conducted to increase soybean tolerance to drought and soil fertility by applying compost and   arbuscular mycorhiza fungi. This system will create environmental friendly agriculture or agricultural system focusing on utilizing biological manure which can improve land productivity. Experiment was arranged in completely randomized design with two treatment factors and three replicated . First factor is type of compost, municipal waste compost , cow manure compost, chicken manu...

  10. Nitrogen, phosphor, and potassium nutrients uptake of soybean (Glycine max (L.) Merril) on three levels of radiation intensities and soil moisture content of latosol

    International Nuclear Information System (INIS)

    Syahbuddin, H.; Apriyana, Y.; Heryani, N.; Darmijati, S.; Las, I.

    1998-01-01

    An experiment was implemented from July to August 1994 in greenhouse of the Ecophysiology Division, Bogor Research Institute for Food Crops using a split-split plot design with three replications. Radiation intensity levels as main plot were: without shelter, 25 percent shelter, and 67 percent shelter. Levels of available water in soil as sub-plot were: less than 25 percent soil water availability, content of soil water availability, and 125 percent soil water availability. Soybean varieties as sub-sub plots were: Wilis, Malabar, and Lokon. The experiment showed that nitrogen and phosphor uptake of Wilis was the highest, 41.228 mg and 1.225 mg per hill, especially under 100 percent light intensity and soil water availability more than 25 percent. Under 25 percent shade the potassium uptake of Wilis was 45.997 mg, this was higher than Malabar. The highest increased in seed dry weight, up to 0.733 g, occurred if soil water content changed from available water to 125 percent water content. One calory decreased in radiation caused 0.006 g decreased in seed dry weight per hill, Malabar variety produced an average of 0.892 g seed dry weight, where each millimeter of water will increased 2.0 mg of dry seed weight. Malabar variety had water use efficiency of 0.043 percent g/ml and radiation use efficiency 0.011 percent g/cal. Malabar variety produced the heaviest 100 good seed (7.293 g), followed by Wilis variety (5.520 g) and Lokon variety (4.597 g) [in

  11. Penampilan Karakter Agronomi 16 Genotip Kedelai (Glycine max L. Merrill pada Pertanaman Tumpangsari dengan Jagung (Zea mays L. Pola 3:1

    Directory of Open Access Journals (Sweden)

    Acep Atma Wijaya

    2015-12-01

    Full Text Available Kedelai merupakan komoditas pertanian yang sangat penting di Indonesia. Namun, produksi kedelai nasional belum dapat memenuhi kebutuhan kedelai nasional. Upaya yang dapat dilakukan adalah dengan menerapkan pola tanam tumpangsari kedelai dengan jagung. Penelitian ini bertujuan untuk mencari genotip kedelai yang mampu beradaptasi pada pertanaman tumpangsari dengan jagung pola 3:1 serta menghitung produktivitas penggunaan lahan setiap genotip pada pertanaman tumpangsari dengan jagung pola 3:1. Penelitian ini menggunakan metode eksperimen Rancangan Acak Kelompok (RAK. 16 genotip kedelai digunakan sebagai perlakuan, dan diulang sebanyak dua kali. Untuk melihat respons genotip pada pertanaman tumpangsari dilakukan dengan uji Least Significant Increase (LSI pada taraf signifikansi 5%. Pendugaan produktivitas lahan pada setiap genotip dihitung berdasarkan nilai Nisbah Kesetaraan Lahan. Hasil penelitian ini menunjukkan genotip kedelai yang memperlihatkan respons paling baik pada pertanaman tumpangsari kedelai jagung dibandingkan kultivar cek untuk tinggi tanaman yaitu genotip BTN 5 dan JT 3, karakter jumlah cabang produktif yaitu genotip BTN 5, karakter luas daun dan indeks luas daun yaitu genotip JT 3, karakter sudut daun yaitu genotip CK 6, karakter bobot per plot yaitu genotip KBI 2, dan Nisbah Kesetaraan Lahan yaitu genotip CK 6 dan KBI 2.Genotip   BTN 1, BTN 2, BTN 5, CK 15, CK 6, JT 3, KA 6, KA 7, KBI 2, KH 8, Cikuray dan Malikka memiliki nilai NKL lebih besar dari 1,0. Soybean is one of important agricultural commodity in Indonesia. However, the national soybean production is not sufficient to meet the needs of national soybean. Effort to do is by applying an intercropping soybean with corn. The objectives of the research was to find soybean genotypes that can adapt to intercropped plantation with corn in pattern of 3 : 1 as well as the productivity of the land use of each genotype in intercropping with maize in 3 : 1 pattern. The research used an experimental method randomized block design (RBD, 16 soybean genotypes as treatments, and repeated twice. To see the response of genotype in intercropping planting was done by using Least Significant Increase (LSI at the level of significant 5%. Estimation of land productivity on each genotype was calculated with Land Equation Ratio value. The results showed that the best response of soybean genotype compared checks cultivar for plant height were genotype BTN 5 and JT 3, character number of productive branches was genotype BTN 5, the character of leaf area and leaf area index was genotype JT 3 , leaf angle character was genotype CK 6, characters of weights per plot was KBI 2 genotype and Land Equation Ratio value were  CK 6 and KBI 2. Genotypes of BTN 1, BTN 2, BTN 5, CK 15, CK 6, JT 3, KA 6, KA 7, KBI 2, KH 8, Cikuray and Malikka had Land Equivalent Ratio values greater than 1.0.

  12. Effet de l'alimentation en eau sur quelques caracteres morphologiques et anatomiques des feuilles de soja. (Glycine max (L) Merrill)

    OpenAIRE

    Vidal, A.; Pognonec, J.C.

    1984-01-01

    Afin de rechercher des caractères pouvant servir de base à l’établissement d’un test de sélection du soja pour la tolérance à la sécheresse, la morphologie et l’anatomie des feuilles sont étudiées. Trois variétés présentant des niveaux de tolérance différents sont cultivées en cuves de végétation, sous 2 régimes d’alimentation en eau : dans le 1er, les besoins de la variété sont entièrement satisfaits ; dans le 2e, un déficit hydrique sévère est appliqué. Dans chaque variété et chaque tra...

  13. Efecto de algunos fungicidas sobre la interacción Rhizoctonia solani Kuhn-Micorriza vesículo arbuscular en soya, Glycine max Merril

    Directory of Open Access Journals (Sweden)

    Sánchez de Prager Marina

    1987-09-01

    Full Text Available En el campo se dispuso de dos preparaciones de suelo: natural y desinfectado químicamente (Ditrapex-CE y en el invernadero de suelo esterilizado con vapor. Se utilizaron los fungicidas Propamocarb, SN-84364, PCNB y Vitavax-300. Se contó con la flora micorrizógena natural y una cepa introducida, Glomus manihotis. R. solani disminuyó en un 50 % la emergencia de la soya, comportándose más agresivo en suelo desinfectado. En los primeros 15 días su ataque se incrementó y redujo el desarrollo de MVA en suelo natural. Al avanzar la edad de la planta decreció su infección. Con relación a la MVA la tendencia es contraria. La presencia de la MVA, incluyendo G. manihotis no incrementó significativamente la materia seca y el rendimiento de la soya. Al desinfectar el suelo los fungicidas afectaron negativamente la infección micorrizógena, mientras que en suelo natural no sucedió este fenómeno, al contrario SN-84364 incrementó su presencia. Este producto es el que menos afecta la simbiosis en el suelo desinfectado. Los fungicidas SN-84364 y PCNB mostraron gran especificidad contra R. solani y Vitavax-300 mayor espectro de acción.With the object to evaluate in the soybeans crop behavior in the interaction of Rhizoctonia solani, vesicular-arbuscular mycorrhizae (VAM and fungicides used to treatment of seed, two different soil preparations were used in the field trials: natural and chemically disinfected (Ditrapex-CE and under greenhouse: using vapor- sterilized. Was utilized the fungicides Propamocarb, SN-84364, PCNB y Vitavax- 300. Be had into account the natural mycorrhizal flora and a source of Glomus manihotis introduced. R. solani reduced the emergence of soybean by 50%, the above-metioned pathogen was more agressive in disinfected soil. In the 15 days first the attack increased and reduced the VAM development in the natural soil. With the age of the plant the pathogen infection decreased. With relation by VAM is contrary the tendency. The presence of VAM, G. manihotis including, not increased significantly the dry mass and yield of the soybean. The fungicides diminished the VAM infection in both chemically and physically disinfected soil, whereas this does not ocurr in natural soil,SN-84364, on the other hand, increased the VAM infection. This product affected least the simbiosis in the disinfected soil. SN-84364 and PCNB exhibitited their great especifity against R. solani and Vitavax-300 a greater spectrum of action.

  14. Effects of heavy metal concentrations (Cd, Zn and Pb) in agricultural soils near different emission sources on quality, accumulation and food safety in soybean [Glycine max (L.) Merrill

    Energy Technology Data Exchange (ETDEWEB)

    Salazar, Maria Julieta [Multidisciplinary Institute of Plant Biology, Pollution and Bioindicator Section, Faculty of Physical and Natural Sciences, National University of Cordoba, Av. Velez Sarsfield 1611, X5016CGA Cordoba (Argentina); Rodriguez, Judith Hebelen, E-mail: jrodriguez@com.uncor.edu [Multidisciplinary Institute of Plant Biology, Pollution and Bioindicator Section, Faculty of Physical and Natural Sciences, National University of Cordoba, Av. Velez Sarsfield 1611, X5016CGA Cordoba (Argentina); Nieto, Gaston Leonardo; Pignata, Maria Luisa [Multidisciplinary Institute of Plant Biology, Pollution and Bioindicator Section, Faculty of Physical and Natural Sciences, National University of Cordoba, Av. Velez Sarsfield 1611, X5016CGA Cordoba (Argentina)

    2012-09-30

    Highlights: Black-Right-Pointing-Pointer Soybean grown near metal sources presents a toxicological hazard from heavy metals for Chinese consumers. Black-Right-Pointing-Pointer Rhizosphere soil is the most suitable compartment for toxicological studies. Black-Right-Pointing-Pointer Soil guidelines should be modified considering the exchangeable metals. - Abstract: Argentina is one of the major producers of soybean in the world, this generates a high global demand for this crop leading to find it everywhere, even close to human activities involving pollutant emissions. This study evaluated heavy metal content, the transfer of metals and its relation to crop quality, and the toxicological risk of seed consumption, through soil and soybean sampling. The results show that concentrations of Pb and Cd in soils and soybeans at several sites were above the maximum permissible levels. The heavy metal bioaccumulation depending on the rhizosphere soil compartment showed significant and high regression coefficients. In addition, the similar behavior of Cd and Zn accumulation by plants reinforces the theory of other studies indicating that these metals are incorporated into the plant for a common system of transport. On the other hand, the seed quality parameters did not show a clear pattern of response to metal bioacumulation. Taken together, our results show that soybeans grown nearby to anthropic emission sources might represent a toxicological hazard for human consumption in a potential Chinese consumer. Hence, further studies should be carried out taking into account the potential negative health effects from the consumption of soybeans (direct or indirect through consumption of meat from cattle) in these conditions.

  15. Physiochemical and Phytochemical Properties of Wax Apple (Syzygium samarangense [Blume] Merrill & L. M. Perry var. Jambu Madu) as Affected by Growth Regulator Application

    Science.gov (United States)

    Moneruzzaman Khandaker, Mohammad; Nasrulhaq Boyce, Amru; Osman, Normaniza; Sharif Hossain, ABM

    2012-01-01

    This study represents the first paper of the effects of growth regulators on the physiochemical and phytochemical properties of the wax apple fruit, a widely cultivated fruit tree in southeast Asia. Net photosynthesis, sucrose phosphate synthase (SPS) activity, peel color, fruit firmness, juice content, pH value, total soluble solids (TSSs), and the sugar acid ratio were all significantly increased in growth regulators (PGRs) treated fruits. The application of gibberellin (GA3), naphthalene acetic acid (NAA), and 2,4-dichlorophenoxy acetic acid (2,4-D) significantly reduced titratable acidity and increased total sugar and carbohydrate content compared to the control. The 50 mg/L GA3, 10 mg/L NAA, and 5 mg/L 2,4-D treatments produced the greatest increases in phenol and flavonoid content; vitamin C content was also higher for these treatments. PGR treatment significantly affected chlorophyll, anthocyanin, and carotene content and produced higher phenylalanine ammonia lyase (PAL) and antioxidant activity levels. There was a positive correlation between peel color and TSS and antioxidant activity and both phenol and flavonoid content and PAL activity and anthocyanin formation. A taste panel assessment was also performed, and the highest scores were given to fruits that had been treated with GA3 or auxin. The study showed that application of 50 mg/L GA3, 10 mg/L NAA, and 5 mg/L 2,4-D once a week from bud development to fruit maturation increased the physiochemical and phytochemical properties of wax apple fruits. PMID:22701370

  16. La pimienta de Jamaica [Pimenta dioica (L.) Merrill, Myrtaceae] en la Sierra Norte de Puebla (México)

    OpenAIRE

    Macía Barco, Manuel Juan

    1998-01-01

    Pimenta dioica, allspice, is a neotropical Myrtaceae distributed in Mesoamerica and the Caribbean region. Its área of distribution in México ranges along East and Southeast parts of the country. The main use of its dried fruits is as spice, being sold in Mexican nacional markets as well as exported to Germany, the United States, Jamaica and Great Britain. Most of the harvest comes from trees growing wild in tropical forests, although lately there is a trend to domesticate and cultivate the pl...

  17. TESTES DE CONDUTIVIDADE ELÉTRICA PARA AVALIAÇÃO DO VIGOR DE SEMENTES DE SOJA (Glycine max (L. Merrill

    Directory of Open Access Journals (Sweden)

    D.C.F.S DIAS

    1996-01-01

    Full Text Available O presente trabalho teve como objetivo investigar a possibilidade de redução do período de condicionamento das sementes nos testes de condutividade elétrica, nos sistemas de massa e individual, e consequentemente, obter indicações mais rápidas sobre a qualidade fisiológica dos lotes. Para tanto, foram utilizados quatro lotes de sementes de soja das variedades IAC-8 e IAC-15 que foram submetidos a estudos específicos de condutividade elétrica de massa e individual (ASA-610, empregando-se períodos de condicionamento de 4, 8, 12, 16, 20 e 24 horas. No sistema de massa foram utilizadas amostras de sementes não danificadas e de sementes fisicamente puras. Nos estudos com o ASA-610 foram testadas as intensidades de corrente elétrica de 95 a 45 mA/semente, em intervalos de 5mA. Além destes foram conduzidos os seguintes testes: germinação, primeira contagem de germinação, envelhecimento artificial e determinação do grau de umidade das sementes. Os resultados indicaram que há possibilidade de redução no período de condicionamento das sementes no teste de condutividade de massa, sendo que os períodos de embebição mais curtos (4 e 8 horas permitiram a identificação de diferenças mais acentuadas entre os lotes, enquanto que leituras realizadas a partir de 16 horas mostraram-se mais sensíveis às variações de vigor das sementes. O referido teste mostrou-se adequado para a identificação de lotes com diferentes níveis de vigor. Já a condutividade individual (ASA-610 revelou eficiência variável de acordo com a variedade avaliada.To investigate the reduction of the seed soaking time, in bulk and individualy, conductivity tests were performed on four seed lots of two soybean varieties (IAC-8 and IAC-15. The following tests were conducted: standard germination, first count of standard germination, accelerated aging and seed moisture. Studies of bulk and individual (ASA-610 seed conductivity were conducted with 4, 8, 12, 16, 20 and 24 hours of soaking. It was concluded that for the bulk conductivity test the shorter imbibition periods (4 and 8 can be used for the detection of wide vigor differences, while imbibition periods of 16, 20 and 24 hours can be used to identify smaller vigor differences among soybean seed lots. This test showed to have good potential as a rapid and efficient method to discriminate soybean seed lots of different qualities. Its use in seed quality control programs can be useful. The efficiency of the ASA-610 varied according to variety.

  18. Resistance to Anticarsia gemmatalis Hübner (Lepidoptera, Noctuidae in transgenic soybean (Glycine max (L. Merrill Fabales, Fabaceae cultivar IAS5 expressing a modified Cry1Ac endotoxin

    Directory of Open Access Journals (Sweden)

    Milena Schenkel Homrich

    2008-01-01

    Full Text Available Somatic embryos of the commercial soybean (Glycine max cultivar IAS5 were co-transformed using particle bombardment with a synthetic form of the Bacillus thuringiensis delta-endotoxin crystal protein gene cry1Ac, the beta-glucuronidase reporter gene gusA and the hygromycin resistance gene hpt. Hygromycin-resistant tissues were proliferated individually to give rise to nine sets of clones corresponding to independent transformation events. The co-bombardment resulted in a co-transformation efficiency of 44%. Many histodifferentiated embryos and 30 well-developed plants were obtained. Twenty of these plants flowered and fourteen set seeds. The integration and expression of the cry1Ac, gusA and hpt transgenes into the genomes of a sample of transformed embryos and all T0, T1, T2 and T3 plants were confirmed by Gus activity, PCR, Southern and western blot, and ELISA techniques. Two T0 plants out of the seven co-transformed plants produced seeds and were analyzed for patterns of integration and inheritance until the T3 generation. Bioassays indicated that the transgenic plants were highly toxic to the velvetbean caterpillar Anticarsia gemmatalis, thus offering a potential for effective insect resistance in soybean.

  19. Effects of heavy metal concentrations (Cd, Zn and Pb) in agricultural soils near different emission sources on quality, accumulation and food safety in soybean [Glycine max (L.) Merrill

    International Nuclear Information System (INIS)

    Salazar, María Julieta; Rodriguez, Judith Hebelen; Nieto, Gastón Leonardo; Pignata, María Luisa

    2012-01-01

    Highlights: ► Soybean grown near metal sources presents a toxicological hazard from heavy metals for Chinese consumers. ► Rhizosphere soil is the most suitable compartment for toxicological studies. ► Soil guidelines should be modified considering the exchangeable metals. - Abstract: Argentina is one of the major producers of soybean in the world, this generates a high global demand for this crop leading to find it everywhere, even close to human activities involving pollutant emissions. This study evaluated heavy metal content, the transfer of metals and its relation to crop quality, and the toxicological risk of seed consumption, through soil and soybean sampling. The results show that concentrations of Pb and Cd in soils and soybeans at several sites were above the maximum permissible levels. The heavy metal bioaccumulation depending on the rhizosphere soil compartment showed significant and high regression coefficients. In addition, the similar behavior of Cd and Zn accumulation by plants reinforces the theory of other studies indicating that these metals are incorporated into the plant for a common system of transport. On the other hand, the seed quality parameters did not show a clear pattern of response to metal bioacumulation. Taken together, our results show that soybeans grown nearby to anthropic emission sources might represent a toxicological hazard for human consumption in a potential Chinese consumer. Hence, further studies should be carried out taking into account the potential negative health effects from the consumption of soybeans (direct or indirect through consumption of meat from cattle) in these conditions.

  20. Effects of heavy metal concentrations (Cd, Zn and Pb) in agricultural soils near different emission sources on quality, accumulation and food safety in soybean [Glycine max (L.) Merrill].

    Science.gov (United States)

    Salazar, María Julieta; Rodriguez, Judith Hebelen; Leonardo Nieto, Gastón; Pignata, María Luisa

    2012-09-30

    Argentina is one of the major producers of soybean in the world, this generates a high global demand for this crop leading to find it everywhere, even close to human activities involving pollutant emissions. This study evaluated heavy metal content, the transfer of metals and its relation to crop quality, and the toxicological risk of seed consumption, through soil and soybean sampling. The results show that concentrations of Pb and Cd in soils and soybeans at several sites were above the maximum permissible levels. The heavy metal bioaccumulation depending on the rhizosphere soil compartment showed significant and high regression coefficients. In addition, the similar behavior of Cd and Zn accumulation by plants reinforces the theory of other studies indicating that these metals are incorporated into the plant for a common system of transport. On the other hand, the seed quality parameters did not show a clear pattern of response to metal bioacumulation. Taken together, our results show that soybeans grown nearby to anthropic emission sources might represent a toxicological hazard for human consumption in a potential Chinese consumer. Hence, further studies should be carried out taking into account the potential negative health effects from the consumption of soybeans (direct or indirect through consumption of meat from cattle) in these conditions. Copyright © 2012 Elsevier B.V. All rights reserved.

  1. PineElm_SSRdb: a microsatellite marker database identified from genomic, chloroplast, mitochondrial and EST sequences of pineapple (Ananas comosus(L.) Merrill).

    Science.gov (United States)

    Chaudhary, Sakshi; Mishra, Bharat Kumar; Vivek, Thiruvettai; Magadum, Santoshkumar; Yasin, Jeshima Khan

    2016-01-01

    Simple Sequence Repeats or microsatellites are resourceful molecular genetic markers. There are only few reports of SSR identification and development in pineapple. Complete genome sequence of pineapple available in the public domain can be used to develop numerous novel SSRs. Therefore, an attempt was made to identify SSRs from genomic, chloroplast, mitochondrial and EST sequences of pineapple which will help in deciphering genetic makeup of its germplasm resources. A total of 359511 SSRs were identified in pineapple (356385 from genome sequence, 45 from chloroplast sequence, 249 in mitochondrial sequence and 2832 from EST sequences). The list of EST-SSR markers and their details are available in the database. PineElm_SSRdb is an open source database available for non-commercial academic purpose at http://app.bioelm.com/ with a mapping tool which can develop circular maps of selected marker set. This database will be of immense use to breeders, researchers and graduates working on Ananas spp. and to others working on cross-species transferability of markers, investigating diversity, mapping and DNA fingerprinting.

  2. Flexibilização espacial e populacional em cultivares de soja de diferentes grupos de maturação no Distrito Federal Glycine Max (L.) Merril

    OpenAIRE

    Cruz, Vinícius França Santa

    2008-01-01

    O trabalho teve como objetivo avaliar a resposta de cultivares de soja aos diferentes arranjos espaciais, variando espaçamento entre linhas e densidades em três cultivares trangênicos com características morfológicas diferentes. Os experimentos foram conduzidos na safra 2006/2007 na fazenda Primavera, distante 60 Km de Brasília-DF. Quatro espaçamentos entre linhas (20, 40, 50, 60 cm) foram combinados com três densidades de plantio em três experimentos isolados, cada um com um cultivar. Par...

  3. The effect of nano-silica fertilizer concentration and rice hull ash doses on soybean (Glycine max (L.) Merrill) growth and yield

    Science.gov (United States)

    Suciaty, T.; Purnomo, D.; Sakya, A. T.; Supriyadi

    2018-03-01

    Agriculture is facing a number of challenges included limited water supply, low nutrient use efficiency, etc affected by climate change. Nano-silica is a product of nanotechnology, the frontier technologies to enhance crop productivity under climate change threats. The purpose of the research was to investigate the effects of nano silica concentration and rice hull ash on growth and yield of soybean. The experiment was conducted at Gagasari village, Cirebon, West Java from March until June 2017. The treatments were arranged by using factorial completely randomized block design with two factors. The first factor was a concentration of nano silica fertilizer consisted of four levels i.e., 0, 1.75, 2.5, and 3.75 ml.l‑1. The second factor was doses of rice hull ash consisted of four levels i.e., 0, 1, 2, and 3 ton.ha‑1. Each treatment combinations was repeated three times. The result showed that concentration of nano silica individually affected the number of leaves and number of branches, NAR and RGR, productive branches at 21, 30-45, and 35 daps, respectively. It also affected the seed dry weight plant‑1 and plot‑1. Meanwhile, doses of rice hull ash affected LAI, NAR, and RGR, 15-30, and 30-45 dap, respectively. Dry seed weight plot‑1 was also affected by doses of rice hull ash. There was an interaction effect between nano-silica concentration and doses of rice hull ash on number pods.plant‑1. Combinations of 2.5 ml.l‑1 nano-silica and 3 ton.ha‑1 of rice hull ash gave the highest number pods.plant‑1.

  4. Identificação de proteínas diferencialmente expressas em folhas de soja (Glycine max (L.) Merrill) em resposta a Phakopsora pachyrhizi.

    OpenAIRE

    Pereira, Mateus Rodrigues

    2011-01-01

    A ferrugem asiática da soja (FAS), cujo agente causal é o fungo Phakopsora pachyrhizi Sydow, é considerada uma das doenças mais agressivas à cultura, pois ainda não há cultivares comerciais imunes ao patógeno. O mecanismo de controle da doença mais utilizado é o uso de fungicidas, o que aumenta o custo de produção e acarreta em problemas ambientais. O controle das doenças de plantas por meio de resistência genética é a forma mais eficaz e econômica. Estudos genômicos e proteômicos têm sido...

  5. Effects of Ozonated Water Treatment and Modified Atmosphere Package on the Decay and Color of Wax Apple Fruit (Syzygium samarangense [Blume] Merrill & L. M. Perry) during Storage

    OpenAIRE

    Shyr, Jeng–Jung; Hsiung, Tung–Chuan; Wakana, Akira

    2017-01-01

    Wax apple is very perishable fruit at room temperature. The aim of this study is to extend its storage limit by using modified atmosphere package (MAP) and ozonated water which is a highly destructive agent for microbial. Wax apples were immersed in ozonated water (0.1, 0.2 and 0.3 ppm) for 4, 8 and 12 minutes, then placed in cardboard boxes, stored at 12°C and evaluated the effect of ozonated water on the fruit quality. Ozonated–water–treated wax apples were packed into low–density polyester...

  6. La gestión de la liquidez del Banco Central Europeo durante la crisis financiera: 2008-2009

    Directory of Open Access Journals (Sweden)

    Carlos Pateiro Rodríguez

    2001-04-01

    Full Text Available En los meses posteriores a la quiebra de Lehman Brothers, en septiembre de 2008, los mercados financieros fueron sometidos a fuertes tensiones. Por su parte, los mercados monetarios sufrieron alteraciones de tal importancia que el Eurosistema hubo de adoptar medidas orientadas a facilitar liquidez a los bancos ante la posibilidad de colapso del mercado interbancario. En este trabajo se analiza la transformación experimentada por el modelo de inyección de liquidez al sistema, en un contexto de grave crisis financiera y económica. Con tipos de interés en descenso, el cambio ha sido radical entre octubre de 2008 y mediados de 2009. Las operaciones de financiación a más largo plazo representaron la primera posición, desplazando a las operaciones principales de financiación semanales, al tiempo que se ampliaba la lista de activos de garantía y un número creciente de entidades acudía a las subastas de liquidez. En la medida en que el BCE decida limitar las subastas de financiación a más largo plazo, adaptándolas a su procedimiento de política monetaria, resulta de gran interés el análisis de la actual situación deudora de bancos y cajas frente al BCE.

  7. Non-standard monetary policy of the ECB: Macroeconomic effects and exit strategy

    Directory of Open Access Journals (Sweden)

    Momirović Dragan

    2014-01-01

    Full Text Available In the initial phases of the global economic and financial crisis ECB reacted by lowering interest rates to a historic minimum. After the crash of Lehman Brothers and strengthening of financial tensions in the EU and later on the sovereign debt crisis in the euro zone, ECB was forced to search for resource in the non-standard monetary policy measures. The ECB non-standard monetary policy changed the structure and the balance sheet size, and through actions and undertaken measures in the crisis which is still ongoing, strives to conduct the policy of the anticipated long-term interest rate. This paper offers a review of the ECB non-standard policy measures applied and the manner in which monetary policy is spilling over on to the banking and the real sector, but also the effects of the balance sheet expansion on the effects of certain macroeconomic variables. VAR model shows that the effects of the ECB balance sheet expansion are having a positive impact on the macroeconomy effects, i.e. on the two variables, output and prices, and the economic growth. The long-term effects of the non-standard monetary policy implementation remain uncertain and bear the risk of resurrection of undesired financial shocks. The manner in which ECB can avoid the uncertainty of these policies, over a long-term, is to start with gradual 'narrowing down of the non-standard policy', e. to create prerequisite for an exit strategy.

  8. Modeling international stock market contagion using multivariate fractionally integrated APARCH approach

    Directory of Open Access Journals (Sweden)

    Zouheir Mighri

    2014-12-01

    Full Text Available The aim of this article is to examine how the dynamics of correlations between two emerging countries (Brazil and Mexico and the US evolved from January 2003 to December 2013. The main contribution of this study is to explore whether the plunging stock market in the US, in the aftermath of global financial crisis (2007–2009, exerts contagion effects on emerging stock markets. To this end, we rely on a multivariate fractionally integrated asymmetric power autoregressive conditional heteroskedasticity dynamic conditional correlation framework, which accounts for long memory, power effects, leverage terms, and time-varying correlations. The empirical analysis shows a contagion effect for Brazil and Mexico during the early stages of the global financial crisis, indicating signs of “recoupling.” Nevertheless, linkages show a general pattern of “decoupling” after the Lehman Brothers collapse. Furthermore, correlations between Brazil and the US are decreased from early 2009 onwards, implying that their dependence is larger in bearish than in bullish markets.

  9. Fragmentation, integration and macroprudential surveillance of the US financial industry: Insights from network science.

    Science.gov (United States)

    Gandica, Yerali; Geraci, Marco Valerio; Béreau, Sophie; Gnabo, Jean-Yves

    2018-01-01

    Drawing on recent contributions inferring financial interconnectedness from market data, our paper provides new insights on the evolution of the US financial industry over a long period of time by using several tools coming from network science. Relying on a Time-Varying Parameter Vector AutoRegressive (TVP-VAR) approach on stock market returns to retrieve unobserved directed links among financial institutions, we reconstruct a fully dynamic network in the sense that connections are let to evolve through time. The financial system analysed consists of a large set of 155 financial institutions that are all the banks, broker-dealers, insurance and real estate companies listed in the Standard & Poors' 500 index over the 1993-2014 period. Looking alternatively at the individual, then sector-, community- and system-wide levels, we show that network sciences' tools are able to support well-known features of the financial markets such as the dramatic fall of connectivity following Lehman Brothers' collapse. More importantly, by means of less traditional metrics, such as sectoral interface or measurements based on contagion processes, our results document the co-existence of both fragmentation and integration phases between firms independently from the sectors they belong to, and doing so, question the relevance of existing macroprudential surveillance frameworks which have been mostly developed on a sectoral basis. Overall, our results improve our understanding of the US financial landscape and may have important implications for risk monitoring as well as macroprudential policy design.

  10. Efectos de la crisis financiera internacional sobre la postura fiscal del gobierno colombiano

    Directory of Open Access Journals (Sweden)

    Ignacio Lozano

    2009-12-01

    Full Text Available La quiebra de Lehman Brothers en septiembre de 2008 marcó el comienzode uno de los peores años en la historia de los mercados financierosinternacionales. Este evento también determinó el inicio de la recesión económica mundial que se extenderá por lo menos tres años. Las cifras han confirmado que prácticamente todos los países industrializados, y la mayor parte de los emergentes, entraron en recesión, con graves efectos sobre el empleo y la pobreza, de manera que el colapso que hoy soporta la población mundial se asemeja a la crisis de los años treinta. Este artículo describe la forma como se gestó la crisis en el sistema financiero de los Estados Unidos y se propagó en el resto de las economías industrializadas. En esta entrega también se describen los canales de transmisión de la crisis hacia los mercados emergentes y, en particular, se muestran los primeros efectos sobre las principales economías de América Latina.

  11. Convenience in white-collar crime: A resource perspective

    Directory of Open Access Journals (Sweden)

    Petter Gottschalk

    2017-03-01

    Full Text Available White-collar offenders have access to resources that make financial crime convenient. In the rare case of crime suspicion, resources are available in terms of professional attorney work, control over internal investigations, and public relations support. Hiring private investigators at an early stage of potential crime disclosure enables the organization to control the investigation mandate and influence the investigation process and the investigation output. Getting an early start on reconstruction of the past in terms of a fraud examination makes it possible for the suspect and the organization to influence what facts are relevant and how facts might be assessed in terms of possible violations of the penal code. Convenience aspects of private investigations are discussed in this article in terms of five internal investigations, two in the United States (General Motors and Lehman Brothers and three in Norway (Telenor VimpelCom, DNB Bank, and Norwegian Football Association. The aim of this research is to contribute insights into convenience associated with internal private investigations.

  12. Building enterprise-wide resilience by integrating business continuity capability into day-to-day business culture and technology.

    Science.gov (United States)

    Alesi, Patrick

    2008-04-01

    This paper follows the development of the business continuity planning (BCP) programme at Lehman Brothers following the events of September 11th. Previous attempts to implement a `traditional' form of BCP had been ineffective, but following the events, the firm began to look at BCP in a new light. This paper deals with three main themes: creating a culture of resiliency, leveraging technology, and building flexible plans. Distributing accountability for BCP to business line managers, integrating BCP change management into the normal course of business, and providing every employee with personalised BCP information breeds a culture of resiliency where people are empowered to react to events without burdensome, hierarchical response and recovery procedures. Building a strong relationship with one's application development community can result in novel, customised BCP solutions; existing systems and data structures can be used to enhance an existing BCP. Even the best plans are often challenged by events; understanding that flexibility is essential to effective incident response is a critical element in the development of a proper business continuity plan.

  13. OSI-774 OSI Pharmaceuticals.

    Science.gov (United States)

    Norman, P

    2001-02-01

    OSI-774 (formerly CP-358774), a quinazoline derivative, is an orally active epidermal growth factor receptor (EGFR) inhibitor which was originally under joint development by Pfizer and OSI Pharmaceuticals (formerly Oncogene Science) for the potential treatment of cancer (eg, ovarian, non-small cell lung cancer (NSCLC) and head and neck). It is being evaluated in phase II trials [304305], [372201]. On 8 January 2001, OSI announced that it had signed an agreement with Roche and Genentech for the global co-development and marketing of OSI-774. The agreement with Genentech covers the United States, that with Roche the rest of the world [395371], [395526]. In June 2000, OSI gained all development and marketing rights for OSI-774 following Pfizer's merger with Warner-Lambert [371439]. In September 2000, Pfizer transferred the IND dossierfor OSI-774 to OSI ahead of the timeline agreed in the June 2000 development and marketing rights agreement [383786]. The phase II trials will assess OSI-774 both as a single agent and in combination with existing chemotherapy regimens [347783]. Phase III trials are expected to be initiated in 2001 [347783]. In October 2000, Lehman Brothers predicted that OSI-774 would move into pivotal trials in thefirst half of 2001 and that the drug would be launched in 2003. The analysts also estimated worldwide sales of US $66 million, $285 million and $461 million in 2003, 2004 and 2005, respectively, and peak sales in excess of US $500 million [395189].

  14. An Overview of Corporate Governance Practices of Selected Islamic Banks

    Directory of Open Access Journals (Sweden)

    Zainab Belal

    2016-05-01

    Full Text Available Complying with Corporate Governance (CG standards is not mandatory but with collapse of many financial institutions, compliance with high standards of CG in banking operation has become a necessity. This is due to the fact that many banks and companies worldwide collapsed as a result of poor corporate governance practices such as Bank of Credit and Commerce International (BCCI 1991, Barings Bank 1995, Lehman Brothers 2008, Enron 2001, WorldCom 2001, etc. Therefore, the objective of this paper is to examine and ascertain whether present level of CG standards practiced by Islamic banks is adequate to prevent or safeguard the banks from collapsing. The approach of the study is to evaluate the effectiveness of board and the various board committees utilizing data published in financial statement of the selected banks. The methodology used in this paper is analytical descriptive to reach accurate results and as more appropriate approach with this research. The study finds out that the selected banks comply with CG standards adopted; however such compliance does not mean that the board, the board committees will be constantly reliable. Therefore, instilling the Islamic values such as the concepts of ih}sân, honesty, and accountability is paramount to prevent CG failures and protect/safeguard the banks from collapsing.

  15. Condições de pH e temperatura para máxima atividade da bromelina do abacaxi (Ananas Comosus L. Merril = Temperature and pH conditions for maximum activity of bromelain extracted from pineapple (Ananas Comosus L. Merril

    Directory of Open Access Journals (Sweden)

    Moacyr Jorge Elias

    2011-04-01

    Full Text Available A bromelina, enzima presente no abacaxi, hidrolisa ligações peptídicas das proteínas; tem aplicação em diversas áreas envolvendo alimentos e medicina. Visando o aproveitamento da bromelina recuperada, a partir dos resíduos da industrialização do fruto(variedade pérola, foram pesquisadas condições de pH e temperatura para maior atividade, empregando caseína como substrato. O extrato foi obtido pela trituração da casca e do talo interno do fruto. A atividade foi expressa em mmol tirosina L-1 min.-1 pela absorbância a280 nm dos aminoácidos aromáticos gerados na hidrólise da caseína. Os ensaios foram efetuados em duplicata para duas relações enzima/substrato: 1/25 e 1/125 (em massa. Foi estabelecido um planejamento experimental em estrela tendo como ponto central pH em7,0 e temperatura de 35°C. Os resultados foram tratados empregando o aplicativo computacional MINITAB 15 da Minitab Inc. que forneceu as equações do modelo e as superfícies de resposta. As equações foram tratadas matematicamente (cálculo diferencial, fornecendo gráficos da melhor atividade em função da temperatura. Observou-se perda daatividade enzimática com a elevação da temperatura para relação 1/25, atribuída à maior presença de enzima livre em comparação com a relação 1/125.Bromelain, the enzyme found in pineapple, hydrolyzes proteins’ peptide bonds, has several applications in the food industry and in medicine. Temperature and pH conditions for highest activity with casein as substrate were investigated from the bromelain recovered from industrialized pineapple (‘pérola’ variety fruit residues. Extract was obtained by grinding fruit rind and its internal stem. The activity was expressed in mmol tyrosine L-1 min.-1 by absorbance at 280 nm of aromatic amino acids produced in casein hydrolysis. Assays were undertaken in duplicate for two enzyme/substrate with ratios: 1/25 and 1/125 (mass. Eight-pointed experimental design was undertaken with central value for pH at 7.0 and for temperature at 35°C. Experimental results were processed by MINITAB 15 (Minitab Inc software which provided model’s equations and surface responses. Equations were mathematically processed by differential calculus producing graphs which exhibit the best activities according to temperatures. Loss of enzyme activity was reported with temperature increase at 1/25 ratio, due to a higher free enzyme, when compared to 1/125 ratio.

  16. EFFECTS OF SUBSTRATUM AND CONTAINERS IN ACCLIMATION OF PINEAPPLE SEEDLINGS [Ananas comosus (L. Merril] CV. PÉROLA EFEITOS DE SUBSTRATOS E RECIPIENTES NA ACLIMATAÇÃO DE PLÂNTULAS DE ABACAXIZEIRO [Ananas comosus (L. Merril] CV. PÉROLA

    Directory of Open Access Journals (Sweden)

    Sarah Brandão Santa Cruz Barboza

    2007-09-01

    Full Text Available

    After the removal of the in vitro culture medium, the survival and growth of micropropagated seedlings are among the main difficulties found in several crops. The objective of this study was to evaluate the behavior of pineapple cv. Pérola seedlings produced in vitro and acclimated in different substrates and containers. The experimental design was completely randomized split plot, with four replicates. The plots (twenty plants consisted of three substrates (sand/plant fiber/humus, Plantmax and sand and the subplots consisted of three containers (a tubet 5cm in diameter by 13cm high, a tubet 5cm in diameter by 24.5cm high and a 10cm x 8cm plastic bag. The combinations of sand/plant fiber/humus with 5x13cm tubet or with a plastic bag, and of Plantmax with 5x13cm tubet provide better growth in ex vitro conditions.

    KEY-WORDS: Culture in vitro; micropropagation; fruitculture.

    A sobrevivência e o crescimento de plântulas micropropagadas, após a remoção do meio de cultivo in vitro, estão entre as principais dificuldades encontradas em várias culturas. O objetivo deste trabalho foi avaliar o comportamento de plântulas de abacaxi cv. Pérola, produzidas in vitro e submetidas a aclimatação em diferentes substratos e recipientes. O delineamento experimental foi inteiramente ao acaso em parcelas subdivididas, com quatro repetições. As parcelas (com vinte plântulas foram constituídas de três substratos (areia/xaxim/húmus, Plantmax e areia e as subparcelas, de três recipientes (tubete com 5cm de diâmetro x 13cm de altura, tubete com 5cm de diâmetro x 24,5cm de altura e saco plástico, com 10cm x 8cm. As combinações areia/xaxim/húmus com tubete pequeno ou com saco plástico e Plantmax com tubete de 5cm diâmetro x 13cm de altura proporcionaram melhores respostas ao crescimento em condições ex vitro.

    PALAVRAS-CHAVE: Cultivo in vitro; micropropagação; fruticultura; parcelas subdivididas.

  17. Ensaio tecnológico e sensorial de soja [Glycine max (L. Merrill] enlatada em estádios verdes e no estádio da maturação de colheita Technological and sensorial assay of soybean [Glycine max (L. Merrill] canned at green stages and at harvest maturation stage

    Directory of Open Access Journals (Sweden)

    M.F.P BARCELOS

    1999-01-01

    Full Text Available Foi estudada a viabilidade de consumo da cultivar de soja IAC PL-1 enlatada como grão verde e sua melhor época de colheita para enlatamento. Para tanto procederam-se cinco colheitas a partir do 48º dia após a floração (DAF até a extinção da coloração verde. O processamento iniciou-se pelo branqueamento das vagens, debulha e enlatamento. Aos cinco lotes obtidos adicionou-se um sexto lote para estudar o efeito do armazenamento. Para qualificar os seis lotes de grãos enlatados foram efetuadas medidas de peso, cor, textura e características do líquido de enlatamento. Foram realizados estudos das propriedades sensoriais dos grãos enlatados para dimensionar a aceitação pela degustação e aparência. O enlatamento foi otimizado para 121ºC com tempo de esterilização em torno de 4 minutos. A maturidade fisiológica dos grãos ocorreu entre o 61º ao 64º DAF. O processo térmico conservou a cor verde dos grãos enlatados e não induziu perda expressiva da massa dos grãos; a textura firme dos grãos aumentou com a maturação. Os provadores demonstraram boa aceitação dos produtos e não ocorreu preferência em relação aos estádios de maturação. O trabalho conclui que grãos verdes de soja IAC PL-1 proporcionam enlatados com boas características técnicas e gustativas. Foi observado que grãos colhidos no ponto convencional de maturação, armazenados e enlatados obtiveram boa aceitação gustativa, concluindo-se que a cultivar IAC PL-1 é também adequada para o consumo e enlatada após o armazenamento.It was investigated the consumption possibility of the soybean cultivar IAC PL-1 canned as green grain and its best harvest time for canning. Five harvests were processed from the 48th day after flowering (DAF until extinction of the green coloration. The canning procedure started by pod bleaching, dehulling and canning. To the five lots obtained, a sixth lot was added to study the effect of storage. To qualify the six lots of canned grains, measures of weight, color, texture were done, as well as characteristics of canning liquid. Studies of the sensorial properties of canned grains to dimensionate both acceptance and aspect was performed. Canning was optimized to 121ºC with sterilization time around four minutes. Grains physiological maturity took place between 61st to 64th DAF. The heat process conserved the green color of canned grains and did not induce significant loss of the mass of grains; the firm texture of grains increased with maturation. The tasters showed good acceptance of the products and there was no preference concerning the maturation stages. The work concluded that green grains of soybean IAC PL-1 provide canned products with very good technical and taste characteristics. It was found that grains harvested at the conventional maturation point stored and canned obtained good taste acceptance, following that the cultivar IAC PL-1 is also suitable to consumption canned after storage.

  18. Determinação de proteína total e escore de aminoácidos de bromelinas extraídas dos resíduos do abacaxizeiro (Ananas comosus, (L. Merril Determination of total protein and aminoacid composition of bromelain extracted from pineapple plant residues (Ananas comosus, (L. Merril

    Directory of Open Access Journals (Sweden)

    Lenice O. FREIMAN

    1999-05-01

    Full Text Available O abacaxi por longo tempo tem sido a fruta não cítrica mais popular nos países tropicais e sub-tropicais, principalmente pelo seu atrativo sabor e aroma, além do refrescante balanço açúcar-ácido que possui, o que certamente, determinou sua importância sócio-econômica. Além dessas características, é fonte da enzima proteolítica bromelina, um produto de alto valor comercial, que não é fabricado no Brasil. O presente trabalho objetivou a determinação do escore de aminoácidos de bromelinas extraídas das várias partes do abacaxizeiro (casca, folha, caule, coroa e polpa, com duas precipitações subseqüentes, utilizando-se como agente precipitante, o etanol p.a. Análises mostraram maior teor de proteínas na bromelina extraída da coroa. Nas duas precipitações a composição de aminoácidos das enzimas obtidas, apresentaram resultados inferiores aos da comercial.For a long time pineapple has been most popular noncitric fruit in tropical and subtropical countries, principally for its attractive flavor and aroma, besides refreshing sugar-acid balance, what certainly determined its social-economic importance. In addition to these characters, it is a source of the proteolytic bromelain enzyme , that is a high valued commercial product not made in Brazil. The present research has aimed in determination the aminoacids composition of extracted bromelain from some parts of the pineapple plant ( peel, leaf, stem, garland and pulp with two subseqüents precipitation’s using ethanol p.a. as precipitating agent. Analysis showed higher protein content in extracted bromelain from the garland. In the two precipitation’s, the aminoacids composition from the obtained enzymes presented lower results than the one from the commercial enzyme.

  19. Composición química, producción de gas in vitro y astringencia en el follaje de Samanea saman (Jacq. Merrill Chemical composition, in vitro gas production and astringency in the foliage of Samanea saman (Jacq. Merrill

    Directory of Open Access Journals (Sweden)

    A Ojeda

    2012-06-01

    Full Text Available Con el objetivo de determinar la composición química, la astringencia, la producción de gas y la degradabilidad ruminal in vitro de la fracción comestible de Samanea saman, durante el año 2009 se realizaron cinco muestreos (febrero, abril, mayo, junio y octubre en plantas localizadas en un bosque semicaducifolio tropical en Venezuela. En cada muestreo se consideraron 10 plantas diferentes, cada una como una réplica evaluada en un diseño completamente aleatorizado. No hubo variación (P>0,05 en la MO (94,1 ± 1,5%, la PC (20,1 ± 1,5%, la hemicelulosa (17,5 ± 3,7%, la celulosa (10,5 ± 2,5%, la lignina (11,1 ± 1,8% y los fenoles totales (2,8 ± 1,1%. De mayo a octubre se observaron los mayores valores (PIn order to determine the chemical composition, astringency, in vitro gas production and ruminal degradability of the edible fraction of Samanea saman, during 2009, five samplings (February, April, May, June and October were conducted on plants located in a semideciduous tropical forest in Venezuela. In each sampling 10 different plants were considered, each as a replicate evaluated in a completely randomized design. OM (94,1 ± 1,5%, CP (20,1 ± 1,5%, hemicellulose (17,5 ± 3,7%, cellulose (10,5 ± 2,5%, lignin (11,1 ± 1,8%, and total phenols (2,8 ± 1,1% did not show variations (P<0,05. From May to October, the highest values (P<0,05 of EE (5,3 ± 0,8%, NDF (44,8 ± 3,3%, ADF (16,7 ± 1,9%, and Ca (1,3 ± 0,2% were observed; while total (P<0,05 and condensed tannins (P<0,01 increased in October (3,75% and 0,99%, respectively. Astringency was not detected from February to May, and had limited values from June to October (0,4 ± 0,2 g Eta/100 g DM. No differences were observed in b (0,04 ± 0,01 mL/h, To (1,2 ± 0,2 h and T½ (21,3 ± 3,3 h with the highest gas potential production in February (63,3 mL/g DM. The OM and NDF degradability was reduced (P<0,05 in April (44,7% and 24,7%, respectively, without differences during the remaining months (51,2 ± 3,4% and 37,7 ± 3,3%, respectively. The edible biomass of S. saman could be used as a nutrient source in silvopastoral systems, with a low condensed tannin content of low biological activity, which causes a positive impact on the non-ammonia nitrogen flow from the rumen

  20. Teores de isoflavonas em grãos inteiros e nos componentes dos grãos de diferentes cultivares de soja (Glycine max (L. Merrill Isoflavone contents of whole soybeans and their components, obtained from different cultivars (Glycine max (L. Merrill

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo da Silva

    2012-06-01

    Full Text Available Devido à maior concentração de isoflavonas nos hipocótilos dos grãos de soja, a indústria de alimentos tem utilizado esse componente do grão como matéria-prima. No presente trabalho, foram quantificados os teores de isoflavonas nas estruturas formadoras do grão de soja (hipocótilo, cotilédones e casca, analisadas por Cromatografia Líquida de Alta Eficiência (CLAE. Foram avaliadas quatro cultivares de sojas especiais: BRS 184, BRS 216, BRS 257 e BRS 267, desenvolvidas pela Embrapa Soja. Todas as cultivares apresentaram maior teor de isoflavonas totais no hipocótilo (média de 2029,32 mg.100 g-1. No grão inteiro (267,16 mg.100 g-1 e nos cotilédones (209,16 mg.100 g-1, os teores de isoflavonas foram cerca de dez vezes menores do que nos hipocótilos. A cultivar BRS 216 apresentou o teor maior de isoflavonas totais no hipocótilo (2583,20 mg.100 g-1. Embora a casca da soja não apresente isoflavonas, observou-se que esses compostos estavam presentes nessa parte do grão numa quantidade média de 105,58 mg.100 g-1, devido à presença de resíduos do hipocótilo e dos cotilédones provenientes do processo de descasque. Essa composição residual da casca favorece sua utilização como matéria-prima fonte de fibras, porque também fornece isoflavonas e outros compostos da soja.Due to the higher concentration of isoflavones in the soybean hypocotyls, the food industry has used this component of the bean as a raw material. This paper reports the isoflavone contents found in the different parts of the bean (hypocotyl, cotyledon and hull as analyzed by High Performance Liquid Chromatography (HPLC. Four special soybean cultivars, BRS 184, BRS 216, BRS 257 and BRS 267, developed by Embrapa Soybean, were evaluated. All the cultivars presented higher contents of total isoflavones in the hypocotyls (average of 2029.32 mg.100 g-1. The isoflavone contents of the whole beans (267.16 mg.100 g-1 and the cotyledons (209.16 mg.100 g-1 were about 10 times lower than that of the hypocotyls. Cultivar BRS 216 presented the highest total isoflavone content in the hypocotyl (2583.20 mg.100 g-1. Although soybean hulls do not contain isoflavones, an average of 105.57 mg.100 g-1 was found in this component, due to the presence of hypocotyl and cotyledon residues resulting from the hulling process. This residual composition of the hulls favors their use as a raw material that is a source of fibers, also providing isoflavones and other soybean compounds.

  1. The New Soviet Military Doctrine and the Future of the Maritime Strategy

    Science.gov (United States)

    1988-09-01

    introduced as a coherent plan by the Secretary of the Navy John Lehman in March, 1984. Secretary Lehman described the strategy a s the maritime...that the supporters of a different naval strategy could make themselves heard. As a result the newly appointed Secretary of the Navy, John Lehman...criticisms. The primary objections to the strategy can be broken down into two fundamental categories: conventional and nuclear. 9Thomas B. Haward

  2. The Impact of Siblings with Disabilities on Their Brothers and Sisters Pursuing a Career in Special Education

    Science.gov (United States)

    Marks, Susan Unok; Matson, Amy; Barraza, Lori

    2005-01-01

    It is well known that growing up with a sibling who has a disability has both positive and negative impacts on the non-disabled sibling (Beckman, 2002; Fisman, Wolf, Ellison, & Freeman, 2000; Gans, 1997; McHugh, 2003). In fact, the concern for ameliorating the potential negative impacts on nondisabled siblings has been a major impetus for the…

  3. A novel splice-site mutation in ATP6V0A4 gene in two brothers with ...

    Indian Academy of Sciences (India)

    ... Tunis El Manar, 1068 Tunis, Tunisia; Molecular Medicine Research Center and Laboratory of Molecular and Medical Genetics, Department of Biological Sciences, University of Cyprus, Kallipoleos 75, 1678 Nicosia, Cyprus; Department of Pediatrics B, Children's Hospital of Tunis, Boulevard 9 avril, Bab Saadoun, Jabbary, ...

  4. HYMNOGRAPHIC 'CANON' AS A “FORM OF THE PLAN” IN “THE BROTHERS KARAMAZOV” BY DOSTOEVSKY

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    Elena Anatolyevna Osokina

    2012-11-01

    Full Text Available The article draws a parallel between divine service and art, using Dostoevsky's last grand masterpiece as an example. We begin by defining the canon as a genre and as a liturgical order. The order of songs in the canon and the liturgical order resemble the sequence of Dostoevsky's novel and make it ordered and recognizable. The form chosen by the author was more organic for Russian consequence than the novel in its Western version and more expressive for a piece of art. By shaping his novel into a canon as a hymnographic piece, Dostoevsky created a special form which helped his novel attain perfection. The form of canon as a hymnographic text is found in the novel's structure (“a form of a plan” which is made clear by the positioning of the life of Zosima. The novel's hidden meaning was thus expressed in its form. The structure of a canon reproduced in a piece of fiction allowed Dostoevsky to link the contemporary and the all-embracing, bring up eternally important issues of losing faith in God and provide true answers in the discovery of new faith in Jesus.

  5. Why Can't I Be More Like My Brother? The Role and Correlates of Sibling Social Comparison Orientation.

    Science.gov (United States)

    Jensen, Alexander C; Pond, Amanda M; Padilla-Walker, Laura M

    2015-11-01

    Siblings play an important role in relational and individual development throughout adolescence and beyond through several mechanisms. Central to this role and the mechanisms of sibling influence is the notion that siblings provide a constant and meaningful frame of reference for social comparison. This study examined the role of sibling social comparison orientation, or the tendency of siblings to compare themselves to one another, on youths' depressive symptoms and family relationships, both directly and by moderating links with parental differential treatment. Participants included 338 youth (M age = 18.34, SD = 1.03; 52 % female). Using hierarchical ordinary least squares regression, we found that a higher sibling social comparison orientation was linked with more depressive symptoms, warmer sibling relationships, and more sibling conflict. Additionally, sibling social comparison orientation moderated links of parental differential treatment with depressive symptoms and prosocial behavior toward family members such that effects were more salient for those with a high comparison orientation. The discussion focuses on the role of sibling comparison in the ways that siblings influence one another's development.

  6. O brother, where art thou? Investment in siblings for inclusive fitness benefits, not father absence, predicts earlier age at menarche.

    Science.gov (United States)

    Smith, Daniel

    2017-10-01

    Numerous studies have indicated that father absence is associated with earlier age at menarche, with many evolutionary theories assuming that father absence is a causal factor that accelerates reproductive development. However, an alternative interpretation suggests that offspring may reproduce earlier in the presence of half- or step-siblings as the indirect fitness benefits to investing in them are lower, relative to delaying reproduction and investing in full siblings. From this perspective, father absence may perform no causal role in facilitating the onset of menarche. Using data from the Avon Longitudinal Study of Parents and Children, I find that individuals with only half- or step-siblings reach reproductive age earlier than those with only full siblings, with no independent effect of father absence. These results suggest that inclusive fitness benefits to investing in siblings, rather than father absence, may predict variation in age at menarche. These results provide a greater understanding of the adaptive mechanisms involved in reproductive decision-making, as well as potential implications for human life-history evolution and cooperative breeding more broadly. © 2017 The Authors.

  7. Wright Brothers Lectureship in Aeronautics: Experience with HiMAT remotely piloted research vehicle - An alternate flight test approach

    Science.gov (United States)

    Deets, D. A.; Brown, L. E.

    1986-01-01

    The highly maneuverable aircraft technology (HiMAT) program explored the various and complex interactions of advanced technologies, such as aeroelastic tailoring, close-coupled canard, and relaxed static stability. A 0.44-subscale remotely piloted research vehicle (RPRV) of a hypothetical fighter airplane was designed and flight-tested to determine the effects of these interactions and to define the design techniques appropriate for advanced fighter technologies. Flexibility and high maneuverability were provided by flight control laws implemented in ground-based computers and telemetered to the vehicle control system during flight tests. The high quality of the flight-measured data and their close correlation with the analytical design modeling proved that the RPRV is a viable and cost-effective tool for developing aerodynamic, structure, and control law requirements for highly maneuverable fighter airplanes of the future.

  8. HOUSING AS AN EXPRESSION OF SELF-IDENTITY IN CONTEMPORARY ALGERIA: THE WORK OF EL-MINIAWY BROTHERS

    OpenAIRE

    Tahar Bellal

    2012-01-01

    This paper tries to shed light on post-traditional environment in Algeria in a post global civilisation era. Some chosen projects implemented in some parts of the country are dealt with in relation to the expression of self identity through housing architecture. The focus of the work is on methods, achievements and implications of the projects. As from the seventies of the last century Algeria witnessed dramatic changes in its physical environment. The cities became the focus of intern...

  9. A novel splice-site mutation in ATP6V0A4 gene in two brothers with ...

    Indian Academy of Sciences (India)

    2014-12-10

    Dec 10, 2014 ... ral hearing loss (SNHL) observed in patients with mutations in the ATP6V1B1 gene (Vargas-Poussou et al. 2006). Indeed,. Stover et al. (2002) demonstrated that young adult patients with ATP6V0A4 mutations could develop a mild SNHL in the long term (Stover et al. 2002). Some dRTA patients without. ∗.

  10. Agents of the Father's law in a society of brothers: A philosophic and psychoanalytic perspective on legitimate use of violence.

    Science.gov (United States)

    Even-Tzur, Efrat; Hadar, Uri

    This paper explores subjective processes of "Agents of Law" - individuals who the state grants the authority to use violence - and the dissonance stemming from the contradictory demands posed on them as legitimate users of violence despite the societal taboo against violence. A conceptual model will be offered based on two theoretical legs, Lacanian psychoanalysis and political theories of legitimacy. Specifically, psychoanalytic ideas would serve to examine unconscious processes, subject position and various identifications related to the question of "self-legitimacy" of Agents of Law. A central link between psychoanalysis and political thought is found in the image of the father and in the triad ruler-God-Father, which calls for an oedipal analysis. A psychoanalytic reading of two philosophical schools that elaborated on the question of legitimacy will be presented, and yield two analytic poles of a model for the understanding of possible subject positions of agents of Law: identification with a "Living Father" vs. identification with a "Dead Father". The psychoanalytic reading will shed light on the limitations of the philosophical perspectives in reflecting on the various (im)possible psychological positions of agents of Law. Finally, then, it will be shown how psychoanalysis helps finding words to characterize different nuances in the coping of agents of Law with the contradictory demands posed on them in an age in which God is dead, the father was murdered and the king was beheaded. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. BIG BROTHER IS WATCHING YOU! TO BE OR NOT TO BE ONLINE... OR SCREEN AS OUR OWN TECHNOLOGICAL ADDRESS

    Directory of Open Access Journals (Sweden)

    Vanda Maria Sousa

    2014-12-01

    Full Text Available This article seeks to answer the question: how the screens are interposed between the subject and reality, in contexts of the New Technologies of Information and Communication, particularly in the case of television screens (in the reality show format and computer screens (by the profusion of social networks? Using the interpretative methodology, our goal is to take as a starting point the etymology of technic and technology to establish the technological nature of man’s relationship with reality. Once this premise is demonstrated, we will convene the Heideggerian concepts (dasein and ge-stell to interpret how the technology of the screen meets a social need for happiness that comes from the media in a world that re-discovers itself as iconic. Each of us is called upon, in our day-to-day life, to an important, special and urgent meeting with the representation of our own selves, against a screen, where will be its own place of happiness. We intend to assess whether ideologies are hiper-evaluated today, especially when translating reality into binary conceptions of the world, projecting dasein on the demand for unity (1, opposing it to failure (0, each time using the screen more like a mirror or a window, and forgetting its function as a ge-stell by making it a promotion, and not doing it as a way to discover dasein, but, instead, as the opening of the simulacra itself.

  12. Leadership, Hermandad (Brother/Sisterhood), and Organizational Culture: Crossing Boundaries to Build Collaborative Relationships among Latino Fraternal Organizations

    Science.gov (United States)

    Heredia, Anna-Maria

    2013-01-01

    The purpose of the study is to explore the identity development and organizational culture of a student organization, the National Association of Latino Fraternal Organizations council (NALFO) by implementing a community of practice approach at a large, public university in southwestern United States. The objective is to construct a sustainable…

  13. Is schooling a family thing? Effects of grandparents, parents, brothers and sisters on the school choices of boys and girls

    NARCIS (Netherlands)

    Plug, E.J.S.

    1999-01-01

    There are various ways in which the family affects individual schooling decisions. To address these family forces at work, this paper asks whether parental human capital and parental income have distinct positive impacts on the childrens human capital formation. Estimates are presented that control

  14. The Antebellum American Textbook Authors' Populist History of Roman Land Reform and the Gracchi Brothers

    Science.gov (United States)

    McInnis, Edward

    2015-01-01

    This essay explores social and political values conveyed by nineteenth century world and universal history textbooks in relation to the antebellum era. These textbooks focused on the histories of ancient Greece and Rome rather than on histories of the United States. I argue that after 1830 these textbooks reinforced both the US land reform and the…

  15. The Brothers Grimm in The Library of the National Museum of Slovenia: the Legacy of Anastazij Grün

    Directory of Open Access Journals (Sweden)

    Urška Pajk

    2013-11-01

    Full Text Available ABSTRACTThe article is focused on the “treasures” of the National Museum of Slovenia Library a part of them being the books of the count Anton Alexander Auersprg writing under the pseudonym of Anastazij Grün. In 1910 his legacy was included into the museum’s book collection. The poet Anastazij Zelenc was an interesting and unique historical personage and a passionate collector of books and other printed materials. He became especially enthusiastic about antique history and folk literature. Thus, it is not surprising to find the Grimm’s literary “production” in his collection. Anastazij Grün is not sufficiently known in Slovenia. Therefore it is convenient to underline his importance at the occasion of the 150th anniversary of the death of the great fairy tale writer, ethnologist and philologist Jacob Grimm (20th September 2013.

  16. Organic Solute Transporter-beta (SLC51B) Deficiency in Two Brothers with Congenital Diarrhea and Features of Cholestasis

    NARCIS (Netherlands)

    Sultan, Mutaz; Rao, Anuradha; Elpeleg, Orly; Vaz, Frédéric M.; Abu Libdeh, Bassam Y.; Karpen, Saul J.; Dawson, Paul A.

    2017-01-01

    Primary bile acid malabsorption (PBAM) is associated with congenital diarrhea, steatorrhea, and a block in the intestinal return of bile acids in the enterohepatic circulation. Mutations in the ileal Na(+) -dependent bile acid transporter (ASBT; SLC10A2) can cause PBAM, but do not appear to account

  17. Organic Solute Transporter-beta (SLC51B) Deficiency in Two Brothers with Congenital Diarrhea and Features of Cholestasis.

    Science.gov (United States)

    Sultan, Mutaz; Rao, Anuradha; Elpeleg, Orly; Vaz, Frédéric M; Abu Libdeh, Bassam Y; Karpen, Saul J; Dawson, Paul A

    2017-09-12

    Primary bile acid malabsorption (PBAM) is associated with congenital diarrhea, steatorrhea, and a block in the intestinal return of bile acids in the enterohepatic circulation. Mutations in the ileal Na + -dependent bile acid transporter (ASBT; SLC10A2) can cause PBAM, but do not appear to account for most familial cases. Another major transporter involved in the intestinal reclamation of bile acids is the heteromeric Organic Solute Transporter alpha-beta (OSTα-OSTβ; SLC51A-SLC51B), which exports bile acid across the basolateral membrane. Here we report the first patients with OSTβ deficiency, clinically characterized by chronic diarrhea, severe fat soluble vitamin deficiency, and features of cholestatic liver disease including elevated serum gamma-glutamyltransferase activity. Whole exome sequencing revealed a homozygous single nucleotide deletion in codon 27 of SLC51B, resulting in a frameshift and premature termination at codon 50. Functional studies in transfected cells showed that the SLC51B mutation resulted in markedly reduced taurocholic acid uptake activity and reduced expression of the OSTα partner protein. The findings identify OSTβ deficiency as a new cause of congenital chronic diarrhea with features of cholestatic liver disease. These studies underscore OSTα-OSTβ's key role in the enterohepatic circulation of bile acids in humans. This article is protected by copyright. All rights reserved. © 2017 by the American Association for the Study of Liver Diseases.

  18. From Napoleon Conquests to the Big Brother Sabotage : Harmonization of the Dutch Historical Censuses in the Semantic Web

    NARCIS (Netherlands)

    Meroño-Peñuela, Albert; Ashkpour, Ashkan

    2014-01-01

    Around the turn of the 18th century, the first integral pop- ulation enumeration was held in the Netherlands during the Batavian Republic. It took over 30 years before the first official census was, by royal decree, organized and conducted in 1829, and was meant to be held from then onwards every

  19. Separating Sisters From Brothers: Ethnic Relations and Identity Politics in the Context of Indigenous Land Titling in Indonesia

    Directory of Open Access Journals (Sweden)

    Stefanie Steinebach

    2017-06-01

    Full Text Available Environmental and social transformations in Jambi province, Indonesia, are inextricably interlinked. Large-scale agro-industrial development and nature conservation policies equally alienate local communities from their agricultural lands and turn land into a scarce resource. Consequently, access to agricultural land becomes increasingly contested, not only between communities and state institutions or companies but also among communities themselves. To secure or restore local ‘indigenous’ land rights against land grabbing and green grabbing by states and companies, indigenous land titling has become a powerful tool all over the world. Ongoing activities of indigenous land titling in Indonesia have been largely perceived as an act of justice by indigenous and land rights activists and affected communities. Yet, a challenging step towards titling is the identification of who is and who is not ‘indigenous’. This highly political process creates ethnicity-based identities tied to rights and possibilities around land as a contested resource. Based on a case study of a national park in central Jambi, this paper shows that what is perceived as an act of justice against the state can also produce injustice among local communities by heavily impacting and transforming local social structures and relations.

  20. Early 20th Century Education in the United States: The Role of the Brothers of Holy Cross

    Science.gov (United States)

    Armstrong, Philip C.

    2007-01-01

    The French Revolution bears an ironic responsibility for generating works of charity. To counteract the devastating social effects of that late 18th century uprising, numerous religious communities were founded in France, among them the Congregation of Holy Cross. The Congregation of Holy Cross, the founding religious community behind the…