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Sample records for left jaw quadrants

  1. Compound odontoma involving the four quadrants of the jaws: a case report and review of the literature.

    Science.gov (United States)

    Erdogan, Özgür; Keceli, Onur; Öztunc, Haluk; Evlice, Burcu; Altug, Hasan Ayberk; Günhan, Ömer

    2014-04-01

    Odontomas are the most common odontogenic tumors, representing 70% of all odontogenic tumors. They may present in two specific forms; compound odontoma forms multiple small tooth-like structures, while complex odontoma forms an amorphous calcified mass. In this report, we present a 27-year-old male patient with multiple compound odontoma occupied regions at his jaws. The odontomas involve both alveolar and basal processes of the maxilla and mandible as well as both maxillary sinuses. Converse to conventional recommended treatment, which is surgical excision of the lesion, the management was removal of the lesion and clinical-radiologic followup. The first year's follow-up findings are presented in this case report.

  2. Intensity modulated radiotherapy with fixed collimator jaws for locoregional left-sided breast cancer irradiation.

    Science.gov (United States)

    Wang, Juanqi; Yang, Zhaozhi; Hu, Weigang; Chen, Zhi; Yu, Xiaoli; Guo, Xiaomao

    2017-05-16

    The purpose of this study is to evaluate the intensity modulated radiotherapy (IMRT) with the fixed collimator jaws technique (FJT) for the left breast and regional lymph node. The targeted breast tissue and the lymph nodes, and the normal tissues were contoured for 16 left-sided breast cancer patients previously treated with radiotherapy after lumpectomy. For each patient, treatment plans using different planning techniques, i.e., volumetric modulated arc therapy (VMAT), tangential IMRT (tangential-IMRT), and IMRT with FJT (FJT-IMRT) were developed for dosimetric comparisons. A dose of 50Gy was prescribed to the planning target volume. The dose-volume histograms were generated, and the paired t-test was used to analyze the dose differences. FJT-IMRT had similar mean heart volume receiving 30Gy (V30 Gy) with tangential-IMRT (1.5% and 1.6%, p = 0.41), but inferior to the VMAT (0.8%, p < 0.001). In the average heart mean dose comparison, FJT-IMRT had the lowest value, and it was 0.6Gy lower than that for the VMAT plans (p < 0.01). A significant dose increase in the contralateral breast and lung was observed in VMAT plans. Compared with tangential-IMRT and VMAT plans, FJT-IMRT reduced the mean dose of thyroid, humeral head and cervical esophageal by 47.6% (p < 0.01) and 45.7% (p < 0.01), 74.3% (p =< 0.01) and 73% (p =< 0.01), and 26.7% (p =< 0.01) and 29.2% (p =< 0.01). In conclusion, compared with tangential-IMRT and VMAT, FJT-IMRT plan has the lowest thyroid, humeral head and cervical esophageal mean dose and it can be a reasonable treatment option for a certain subgroup of patients, such as young left-breast cancer patients and/or patients with previous thyroid disease.

  3. Right upper quadrant pain

    International Nuclear Information System (INIS)

    Ralls, P.W.; Colletti, P.M.; Boswell, W.D. Jr.; Halls, J.M.

    1984-01-01

    Historically, assessment of acute right upper quadrant abdominal pain has been a considerable clinical challenge. While clinical findings and laboratory data frequently narrow the differential diagnosis, symptom overlap generally precludes definitive diagnosis among the various diseases causing acute right upper quadrant pain. Fortunately, the advent of newer diagnostic imaging modalities has greatly improved the rapidity and reliability of diagnosis in these patients. An additional challenge to the physician, with increased awareness of the importance of cost effectiveness in medicine, is to select appropriate diagnostic schema that rapidly establish accurate diagnoses in the most economical fashion possible. The dual goals of this discussion are to assess not only the accuracy of techniques used to evaluate patients with acute right upper quadrant pain, but also to seek out cost-effective, coordinated imaging techniques to achieve this goal

  4. Jaw Dislocation

    Science.gov (United States)

    ... used to temporarily stabilize the jaw after a fracture or dislocation. More Information Mouth Healthy Resources In This Article Figure 1 Putting a Dislocated Jaw Back in Place Figure 2 Barton Bandage Urgent Dental Problems Introduction to Urgent Dental Problems Fractured, Loosened, ...

  5. SU-E-T-59: A Novel Multi-Beam Dynamic IMRT with Fixed-Jaw Technique for Left Breast Cancer Patients with Regional Lymph Nodes Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J; Yang, Z; Hu, W [Fudan University Shanghai Cancer Center, Shanghai (China)

    2015-06-15

    Purpose: This study was to investigate the dosimetric benefit of a novel intensity modulated radiation therapy (IMRT) technique for irradiating the left breast and regional lymph node (RLN). Methods: The breast and RLN (internal mammary node and periclavicular node) and normal tissue were contoured for 16 consecutive left-sided breast cancer patients previously treated with RT after lumpectomy. Nine equi-spaced fields IMRT (9 -field IMRT), tangential multi-beam IMRT (tangential-IMRT) and IMRT with fixed-jaw technique (FJT-IMRT) were developed and compared with three-dimensional conformal RT (3DCRT). Prescribed dose was 50 Gy in 25 fractions. Dose distributions and dose volume histograms were used to evaluate plans. Results: All IMRTs achieved similar target coverage and substantially reduced heart V30 and V20 compared to the 3DCRT. The average heart mean dose had different changes, which were 9.0Gy for 9-field IMRT, 5.7Gy for tangential-IMRT and 4.2Gy for FJT-IMRT. For the contralateral lung and breast, the 9-field IMRT has the highest mean dose; and the FJT-IMRT and tangential-IMRT had similar lower value. For the thyroid, both 9-field IMRT and FJT-IMRT had similar V30 (20% and 22%) and were significantly lower than that of 3DCRT (34%) and tangential-IMRT (46%). Moreover, the thyroid mean dose of FJT-IMRT is the lowest. For cervical esophagus and humeral head, the FJT-IMRT also had the best sparing. Conclusion: All 9-field IMRT, tangential-IMRT and FJT-IMRT had superiority for targets coverage and substantially reduced the heart volume of high dose irradiation. The FJT-IMRT showed advantages of avoiding the contralateral breast and lung irradiation and decreasing the thyroid, humeral head and cervical esophagus radiation dose at the expense of a slight monitor units (MUs) increasing.

  6. Eosinophilic granuloma in jaw bone: a pare pediatric case report ...

    African Journals Online (AJOL)

    Case Details: Herein, we report a case of eosinophilic granuloma in a ten years old boy involving posterior quadrants upper and lower jaws as a destructive lesion involving gingiva, periodontium and alveolar bone. Involvement of other bones is ruled out by nucleotide imaging study. Conclusion: EG should be considered ...

  7. Corrective Jaw Surgery

    Medline Plus

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  8. Corrective Jaw Surgery

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    Full Text Available ... and Craniofacial Surgery Cleft Lip/Palate and Craniofacial Surgery A cleft lip may require one or more ... find out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment ...

  9. Corrective Jaw Surgery

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  10. Corrective Jaw Surgery

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    Full Text Available ... Facial Injury / Trauma Surgery Facial trauma injuries include fractures of the upper and lower jaws and the ... Facial Injury / Trauma Surgery Facial trauma injuries include fractures of the upper and lower jaws and the ...

  11. Broken or dislocated jaw

    Science.gov (United States)

    ... problems Numbness of part of the jaw or face Problems aligning the teeth Swelling ... worse with movement Bruising and swelling of the face, bleeding from ... widely, or problem closing the mouth Jaw moving to one side ...

  12. Alexia and quadrant-amblyopia

    DEFF Research Database (Denmark)

    Habekost, Thomas; Starrfelt, Randi

    2006-01-01

    Reading difficulties caused by hemianopia are well described. We present a study of alexia in a patient (NT) with a milder visual field deficit. The patient had suffered a cerebral haemorrhage causing damage to the left occipital cortex and underlying white matter. NT's text reading was slow...

  13. Improvement of periodontal parameters in untreated quadrants after surgical periodontal therapy at adjacent quadrants.

    Science.gov (United States)

    Radvar, Mehrdad; Mardani, Nima; Mellati, Ehsan; Habibi, Mehdi

    2009-04-01

    Once full-mouth surgery is planned following the non-surgical phase for a patient with chronic periodontitis, it often does not undergo revision during the surgical period. The aim of this study was to find out whether surgical treatments performed on each quadrant would have any influence on the periodontal status of the untreated quadrants. Twenty patients with chronic periodontitis were selected and received full-mouth scaling and root planing. After 8 weeks, quadrant-wise surgery was performed during four consecutive sessions at 2-week intervals for sites with probing depth (PD) > or = 5 mm and bleeding on probing (BOP). Clinical parameters, including PD, BOP, and clinical attachment level, were recorded at baseline, at each session prior to surgery, and 8 weeks after the last surgical visit. Only the data recorded for the last-treated quadrant are presented in this article. Marked differences were found in the clinical measurements of the last-treated quadrant among all visits. A significant improvement in the clinical parameters of the last-treated quadrant between sessions two and five were mostly related to the treatment of the other three quadrants. The treatment plan made at the time of reassessment of the initial phase of therapy should be considered provisional, and it should be open to revision prior to each surgical visit to reconfirm or modify the treatment plan previously devised for the remaining quadrant(s).

  14. Corrective Jaw Surgery

    Medline Plus

    Full Text Available ... their surgery, orthognathic surgery is performed to correct functional problems. Jaw Surgery can have a dramatic effect on many aspects of life. Following are some of the conditions that may ... front, or side Facial injury Birth defects Receding lower jaw and ...

  15. Dental diseases and radionuclide imaging of the jaws.

    Science.gov (United States)

    Arias, Jose A; Pardo, Carlos; Olmos, Antonio; Cuadrado, Maria L; Ruibal, Alvaro

    2004-03-01

    The aim of this study was to compare the results of radionuclide bone scans of the jaws with data obtained at the nuclear medicine department from a brief and feasible dental history, taking special account of cases with a positive scan and no recent dental events. Ninety-eight patients undergoing radionuclide bone scan as part of their diagnosis in non-dental, oncological and non-oncological diseases were imaged with 99mTc-labelled oxidronate. Superior and inferior halves of the mandible and maxilla (392 quadrants) were regarded as normal or having an abnormally high uptake. A recent (1 year) dental history was also obtained through a brief questionnaire and data were referred to each quadrant of the jaws. The association between the bone scan and dental disease was assessed by means of the chi-squared test. The overall results of scintigraphy and history coincided in 66 patients (46 with abnormal and 20 with normal findings; P = 0.002). Twenty-five patients had a positive scintigram without any known dental disorder. Results of scintigraphy and history coincided in 254 quadrants (78 with abnormal and 176 with normal findings; P < 0.001). Eighty-three quadrants had hot spots in the scintigram without any known dental lesion. It can be concluded that abnormal jaw scintigrams are frequent in patients without known dental disease, and this may indicate silent osteoblastic activity. These observations should be reported to the dentist for several reasons. First, they may reveal asymptomatic dental lesions. Second, the use of oral prostheses and implants is increasing and they require the support of healthy alveolar bone.

  16. Corrective Jaw Surgery

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    Full Text Available ... and orthodontist understand that this is a long-term commitment for you and your family, and will ... face, mouth and jaw surgery Contact Us Sitemap Terms of Use Privacy Policy © Copyright AAOMS 2008-2018 ...

  17. Crocodile jaw sign

    Directory of Open Access Journals (Sweden)

    Brij Sharma

    2016-01-01

    Full Text Available This teaching image highlights the CT abdominal imaging finding of 'crocodile jaw sign' which should raise concern about the presence of an incomplete annular pancreas which causes partial encasement of the duodenum.

  18. Corrective Jaw Surgery

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    Full Text Available ... jaw surgery.™ What We Do Who We Are News Videos Contact Find a Surgeon What We Do ... out more. Who We Are Find a Surgeon News Videos Contact Administration of Anesthesia Cleft Lip/Palate ...

  19. Corrective Jaw Surgery

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    Full Text Available ... It can also invite bacteria that lead to gum disease. Click here to find out more. Who We ... It can also invite bacteria that lead to gum disease. Click here to find out more. Corrective Jaw ...

  20. Corrective Jaw Surgery

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    Full Text Available ... in face, mouth and jaw surgery.™ What We Do Who We Are News Videos Contact Find a Surgeon What We Do Anesthesia Anesthesia Oral and maxillofacial surgeons are extensively ...

  1. Corrective Jaw Surgery

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    Full Text Available AAOMS - Oral and maxillofacial surgeons. The experts in face, mouth and jaw surgery.™ What We Do Who ... surgeons surgically treat the soft tissues of the face, mouth and gums to improve function, appearance and ...

  2. Corrective Jaw Surgery

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    Full Text Available ... can also invite bacteria that lead to gum disease. Click here to find out more. Who We ... can also invite bacteria that lead to gum disease. Click here to find out more. Corrective Jaw ...

  3. Corrective Jaw Surgery

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    Full Text Available ... surgery, orthognathic surgery is performed to correct functional problems. Jaw Surgery can have a dramatic effect on ... without straining Chronic mouth breathing Sleep apnea (breathing problems when sleeping, including snoring) Your dentist, orthodontist and ...

  4. [Studies on the standardization of parameters for jaw movement analysis--6 degree-of-freedom jaw movements analysis].

    Science.gov (United States)

    Takeuchi, Hisahiro; Bando, Eiichi; Abe, Susumu

    2008-07-01

    To establish standardized evaluating methods for jaw movements analysis. In this paper, we investigated evaluating parameters for 6 degree-of-freedom jaw movements data. Recorded data of jaw border movements from 20 male adults were employed as basic samples. The main parameters were as follows: 1. The displacement of an intercondylar midpoint: the length of a straight line between 2 positions of this point, the intercuspal position and other jaw position. 2. The angle of intercondylar axes: the angle between 2 position of the intercondylar axis, the intercuspal position and other jaw position. 3. The angle of incisal-condylar planes: the angle between 2 position of the plane, the intercuspal position and other jaw position (this plane was defined with the incisal point and condylar points of both sides 4. The mandibular motion range index: quantitative values calculated with 2 of 3 parameters described above. The mandibular motion range index showed a close correlation with respective projected areas of the incisal paths, with the projected area of sagittal border movements on the sagittal plane r = 0.82 (p movements on the frontal plane: left lateral border movements r = 0.92 (p movements r = 0.84 (p movements data and relative relationship between the intercuspal position and other jaw position. They were independent of reference coordinate systems and could measure jaw movement quantitatively.

  5. Efficacy of the Dynamic Jaw Mode in Helical Tomotherapy With Static Ports for Breast Cancer.

    Science.gov (United States)

    Sugie, Chikao; Manabe, Yoshihiko; Hayashi, Akihiro; Murai, Taro; Takaoka, Taiki; Hattori, Yukiko; Iwata, Hiromitsu; Takenaka, Ran; Shibamoto, Yuta

    2015-08-01

    The recently developed dynamic jaw technology of tomotherapy can reduce craniocaudal dose spread without much prolonging the treatment time. This study aimed to investigate the efficacy of the dynamic jaw mode for tomotherapy of breast cancer. Static tomotherapy plans of the whole breast and supraclavicular regional lymph nodes, and plans for the whole breast only were generated in 25 patients with left-sided breast cancer. Plans with a field width of 2.5 or 5 cm with the dynamic or fixed jaw modes were made for each patient. The prescribed dose was 50 Gy in 25 fractions. In whole breast and supraclavicular nodal radiotherapy, dose distributions and homogeneity of the planning target volume (PTV) with the dynamic jaw mode were slightly inferior to those with the fixed jaw mode with a 5-cm field width (P jaw mode than with the fixed jaw mode with a 5-cm field width (P breast radiotherapy, mean doses of the skin and healthy tissues were lower with the dynamic jaw mode than with the fixed jaw mode with a 5-cm field width (P jaw mode provided better sparing of organs at risks with minimal disturbance of dose-volume indices of PTV. Considering the treatment time, the 5-cm-field dynamic jaw mode is more efficient than the 2.5-cm fixed jaw mode. © The Author(s) 2014.

  6. Nonodontogenic Tumors of the Jaws.

    Science.gov (United States)

    Dyalram, Donita; Aslam-Pervez, Nawaf; Lubek, Joshua E

    2016-02-01

    Nonodontogenic tumors of the jaws are common in the pediatric population, accounting for approximately 70% of pediatric jaw tumors. This article focuses on the clinical characteristics and management of the benign nonodontogenic tumors (nonaggressive and aggressive) of the jaws most commonly encountered in children. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Corrective Jaw Surgery

    Medline Plus

    Full Text Available AAOMS - Oral and maxillofacial surgeons. The experts in face, mouth and jaw surgery.™ What We Do Who We Are News Videos Contact Find ... Surgeon What We Do Anesthesia Anesthesia Oral and maxillofacial surgeons are extensively trained to appropriately administer local ...

  8. Corrective Jaw Surgery

    Medline Plus

    Full Text Available ... It can also invite bacteria that lead to gum disease. Click here to find out more. Who We Are Find a Surgeon News Videos Contact Anesthesia Cleft Lip/Palate and Craniofacial Surgery Corrective Jaw Surgery Dental Implant Surgery Extractions and Other Oral Surgeries Facial Cosmetic ...

  9. Recurrent Upper Quadrant Pain: A Fish Bone Secondary to Gastric Perforation and Liver Abscess

    Directory of Open Access Journals (Sweden)

    Hui Liang

    2011-12-01

    Full Text Available A 60-year-old male patient was admitted to our hospital for recurrent upper quadrant pain for 1 month. He had a past history of coronary artery disease. After admission, he repeatedly suffered from high-grade fever, chills and upper quadrant pain. Computed tomography (CT showed a round hypodense mass in the left lobe of the liver, approximately 2.7 × 2.2 cm in size, and a fish bone was confirmed by surgery in the left lobe of liver. The patient was cured completely after surgical removal of the fish bone and liver abscess. CT scan 1 month after discharge showed that the liver abscess had disappeared completely.

  10. Switched Mode Four-Quadrant Converters

    CERN Document Server

    Thurel, Y

    2015-01-01

    This paper was originally presented at CAS-2004, and was slightly modified for CAS-2014. It presents a review of the key parameters that impact the design choices for a true four-quadrant power converter, in the range 1-10 kW, mainly based on switching mode converter topology. This paper will first describe the state-of-the-art for this power converter family, giving the drawbacks and advantages of different possible solutions. It will also present practical results obtained from the CERN-designed converter. It will finally give some important tips regarding critical phases like test one, when conducting a project dealing with this type of power converter.

  11. One-Quadrant Switched-Mode Power Converters

    CERN Document Server

    Petrocelli, R.

    2015-06-15

    This article presents the main topics related to one-quadrant power convert- ers. The basic topologies are analysed and a simple methodology to obtain the steady-state output–input voltage ratio is set out. A short discussion of dif- ferent methods to control one-quadrant power converters is presented. Some of the reported derived topologies of one-quadrant power converters are also considered. Some topics related to one-quadrant power converters such as syn- chronous rectification, hard and soft commutation, and interleaved converters are discussed. Finally, a brief introduction to resonant converters is given.

  12. In vivo precision of conventional and digital methods for obtaining quadrant dental impressions.

    Science.gov (United States)

    Ender, Andreas; Zimmermann, Moritz; Attin, Thomas; Mehl, Albert

    2016-09-01

    Quadrant impressions are commonly used as alternative to full-arch impressions. Digital impression systems provide the ability to take these impressions very quickly; however, few studies have investigated the accuracy of the technique in vivo. The aim of this study is to assess the precision of digital quadrant impressions in vivo in comparison to conventional impression techniques. Impressions were obtained via two conventional (metal full-arch tray, CI, and triple tray, T-Tray) and seven digital impression systems (Lava True Definition Scanner, T-Def; Lava Chairside Oral Scanner, COS; Cadent iTero, ITE; 3Shape Trios, TRI; 3Shape Trios Color, TRC; CEREC Bluecam, Software 4.0, BC4.0; CEREC Bluecam, Software 4.2, BC4.2; and CEREC Omnicam, OC). Impressions were taken three times for each of five subjects (n = 15). The impressions were then superimposed within the test groups. Differences from model surfaces were measured using a normal surface distance method. Precision was calculated using the Perc90_10 value. The values for all test groups were statistically compared. The precision ranged from 18.8 (CI) to 58.5 μm (T-Tray), with the highest precision in the CI, T-Def, BC4.0, TRC, and TRI groups. The deviation pattern varied distinctly depending on the impression method. Impression systems with single-shot capture exhibited greater deviations at the tooth surface whereas high-frame rate impression systems differed more in gingival areas. Triple tray impressions displayed higher local deviation at the occlusal contact areas of upper and lower jaw. Digital quadrant impression methods achieve a level of precision, comparable to conventional impression techniques. However, there are significant differences in terms of absolute values and deviation pattern. With all tested digital impression systems, time efficient capturing of quadrant impressions is possible. The clinical precision of digital quadrant impression models is sufficient to cover a broad variety of

  13. Unexplained right upper quadrant abdominal pain? do not forget the ...

    African Journals Online (AJOL)

    Background: Right upper quadrant abdominal pain is a common reason for consulting a gastroenterologist. Commonly, it portends pathological processes occurring in the liver, gall bladder, or the gut however, unusual causes have been reported. We report cervical intervertebral disc prolapse causing right upper quadrant ...

  14. Four-quadrant flyback converter for direct audio power amplification

    DEFF Research Database (Denmark)

    Ljusev, Petar; Andersen, Michael Andreas E.

    2005-01-01

    This paper presents a bidirectional, four-quadrant flyback converter for use in direct audio power amplification. When compared to the standard Class-D switching audio power amplifier with a separate power supply, the proposed four-quadrant flyback converter provides simple solution with better...

  15. Four quadrant control of induction motors

    Science.gov (United States)

    Hansen, Irving G.

    1991-01-01

    Induction motors are the nation's workhorse, being the motor of choice in most applications due to their simple rugged construction. It has been estimated that 14 to 27 percent of the country's total electricity use could be saved with adjustable speed drives. Until now, induction motors have not been suited well for variable speed or servo-drives, due to the inherent complexity, size, and inefficiency of their variable speed controls. Work at NASA Lewis Research Center on field oriented control of induction motors using pulse population modulation method holds the promise for the desired drive electronics. The system allows for a variable voltage to frequency ratio which enables the user to operate the motor at maximum efficiency, while having independent control of both the speed and torque of an induction motor in all four quadrants of the speed torque map. Multiple horsepower machine drives were demonstrated, and work is on-going to develop a 20 hp average, 40 hp peak class of machine. The pulse population technique, results to date, and projections for implementation of this existing new motor control technology are discussed.

  16. Switched-mode converters (one quadrant)

    CERN Document Server

    Barrade, P

    2006-01-01

    Switched-mode converters are DC/DC converters that supply DC loads with a regulated output voltage, and protection against overcurrents and short circuits. These converters are generally fed from an AC network via a transformer and a conventional diode rectifier. Switched-mode converters (one quadrant) are non-reversible converters that allow the feeding of a DC load with unipolar voltage and current. The switched-mode converters presented in this contribution are classified into two families. The first is dedicated to the basic topologies of DC/DC converters, generally used for low- to mid-power applications. As such structures enable only hard commutation processes, the main drawback of such topologies is high commutation losses. A typical multichannel evolution is presented that allows an interesting decrease in these losses. Deduced from this direct DC/DC converter, an evolution is also presented that allows the integration of a transformer into the buck and the buck–boost structure. This enables an int...

  17. 3D MRI for Quantitative Analysis of Quadrant Percent Breast Density: Correlation with Quadrant Location of Breast Cancer.

    Science.gov (United States)

    Chen, Jeon-Hor; Liao, Fuyi; Zhang, Yang; Li, Yifan; Chang, Chia-Ju; Chou, Chen-Pin; Yang, Tsung-Lung; Su, Min-Ying

    2017-07-01

    Breast cancer occurs more frequently in the upper outer (UO) quadrant, but whether this higher cancer incidence is related to the greater amount of dense tissue is not known. Magnetic resonance imaging acquires three-dimensional volumetric images and is the most suitable among all breast imaging modalities for regional quantification of density. This study applied a magnetic resonance imaging-based method to measure quadrant percent density (QPD), and evaluated its association with the quadrant location of the developed breast cancer. A total of 126 cases with pathologically confirmed breast cancer were reviewed. Only women who had unilateral breast cancer located in a clear quadrant were selected for analysis. A total of 84 women, including 47 Asian women and 37 western women, were included. An established computer-aided method was used to segment the diseased breast and the contralateral normal breast, and to separate the dense and fatty tissues. Then, a breast was further separated into four quadrants using the nipple and the centroid as anatomic landmarks. The tumor was segmented using a computer-aided method to determine its quadrant location. The distribution of cancer quadrant location, the quadrant with the highest QPD, and the proportion of cancers occurring in the highest QPD were analyzed. The highest incidence of cancer occurred in the UO quadrant (36 out of 84, 42.9%). The highest QPD was also noted most frequently in the UO quadrant (31 out of 84, 36.9%). When correlating the highest QPD with the quadrant location of breast cancer, only 17 women out of 84 (20.2%) had breast cancer occurring in the quadrant with the highest QPD. The results showed that the development of breast cancer in a specific quadrant could not be explained by the density in that quadrant, and further studies are needed to find the biological reasons accounting for the higher breast cancer incidence in the UO quadrant. Copyright © 2017 The Association of University Radiologists

  18. Benign Jaw Lesions.

    Science.gov (United States)

    Gohel, Anita; Villa, Alessandro; Sakai, Osamu

    2016-01-01

    There are both odontogenic and nonodontogenic benign lesions in the maxilla and mandible. These lesions may have similar imaging features, and the key radiographic features are presented to help the clinician narrow the differential diagnosis and plan patient treatment. Both intraoral and panoramic radiographs and advanced imaging features are useful in assessing the benign lesions of the jaws. The location, margins, internal contents, and effects of the lesions on adjacent structures are important features in diagnosing the lesions. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. New Whole-House Solutions Case Study: Quadrant Homes

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-02-01

    Quadrant moved ducts and high efficiency furnace inside conditioned space on nearly all 300 customizable house plans. The builder uses dry, true factory-assembled walls, extensive air sealing, and just in time delivery for pre-sold homes.

  20. Lesions of the Jaw.

    Science.gov (United States)

    Mosier, Kristine M

    2015-10-01

    Imaging of lesions within the maxilla and mandible is often fraught with difficulty owing to the similarity in the imaging appearance of a diverse array of pathological processes. Principally, lesions arise from either odontogenic sources or from primary bone lesions. The response of the cancellous and cortical bone to pathologic insult can be expressed either through an osteolytic or an osteoblastic response; thus the majority of lesions within the jaws can be classified as cystic or lytic appearing, sclerotic, or a mixture of the two. This article will review the imaging features of the most common cysts, fibro-osseous lesions, benign and malignant neoplasms, and highlight those features key to the differential diagnosis. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Pediatric jaw tumors: Our experience.

    Science.gov (United States)

    Saxena, Susmita; Kumar, Sanjeev; Pundir, Siddharth

    2012-01-01

    Reports of series of central jaw tumours in children are rare hence predicting their biological behaviour as well as treatment, prognosis have not been documented from this part of the world. To study retrospectively, the paediatric central jaw tumours, reported to our institute with relation to site of occurrence, presentation and biological behaviour. All consecutive patients (lesions formed the study population. Patients fulfilling the inclusion criteria were only considered for further study. The entire study material was analyzed and grouped into various categories for logical conclusions. The data accumulated were grouped, entered and analyzed. Sixty-one cases fulfilled the criteria. Gender distribution was equal, with mandible predominance (2.2:1) and a predominance of non-odontogenic lesions (2:1). There were 4 malignant and 57 benign conditions. Anterior jaw lesions were 23 while 38 were present in the posterior region of jaws (1:1:6). The pattern of central jaw tumours presentation in children from this part of India has been documented. In this study, paediatric jaw tumours are less common compared to those in adults with non-odontogenic tumours being common. The finding of the present study indicates that an impacted tooth, beyond the eruption time deserves more attention for the reason of associated pathologies in children.

  2. Osteonecrosis of the jaw

    Energy Technology Data Exchange (ETDEWEB)

    Reid, Ian R.; Cundy, Tim [University of Auckland, Faculty of Medical and Health Sciences, Auckland (New Zealand)

    2009-01-15

    Osteonecrosis of the jaw (ONJ) was first reported in the dental literature in 2003. The term was coined to describe a spectrum of dental problems seen in cancer patients treated with high doses of intravenous bisphosphonates for the prevention of skeletal-related events. By consensus, the syndrome is now defined by the presence of exposed bone in the mouth which fails to heal after appropriate intervention over a period of 6 or 8 weeks. It is most common in patients with breast or prostate cancers, or multiple myeloma treated with bisphosphonates, of whom about 5% develop the condition. In patients receiving the much lower drug doses used in osteoporosis, the incidence appears to be {proportional_to}1/100,000 patient-years, probably comparable to that in the general population. It is likely that ONJ results from direct drug toxicity to cells of bone and soft tissue. The bone in ONJ lesions does not appear to be 'frozen' but rather there is very active bone resorption taking place, which is likely to be responsible for the local release at high concentrations of bisphosphonates. Infection probably plays a pivotal role in driving this resorption, so its active management is critical. Obvious abnormalities are apparent with a variety of radiologic modalities, and it is not clear that radiographs are inferior to other approaches. Most authors favor a conservative approach to surgical debridement of the lesions. (orig.)

  3. Efficacy of the Dynamic Jaw Mode in Helical Tomotherapy With Static Ports for Breast Cancer

    OpenAIRE

    Sugie, Chikao; Manabe, Yoshihiko; Hayashi, Akihiro; Murai, Taro; Takaoka, Taiki; Hattori, Yukiko; Iwata, Hiromitsu; Takenaka, Ran; Shibamoto, Yuta

    2015-01-01

    The recently developed dynamic jaw technology of tomotherapy can reduce craniocaudal dose spread without much prolonging the treatment time. This study aimed to investigate the efficacy of the dynamic jaw mode for tomotherapy of breast cancer. Static tomotherapy plans of the whole breast and supraclavicular regional lymph nodes, and plans for the whole breast only were generated in 25 patients with left-sided breast cancer. Plans with a field width of 2.5 or 5 cm with the dynamic or fixed jaw...

  4. A CMOS four-quadrant analog current multiplier

    NARCIS (Netherlands)

    Wiegerink, Remco J.

    1991-01-01

    A CMOS four-quadrant analog current multiplier is described. The circuit is based on the square-law characteristic of an MOS transistor and is insensitive to temperature and process variations. The circuit is insensitive to the body effect so it is not necessary to place transistors in individual

  5. In the Jaws of Death

    DEFF Research Database (Denmark)

    Clasen, Mathias

    and produced in thousands an abiding, profound terror of the sea. Jaws gets its peculiar power from successfully immersing its audience in a primal scenario of predation by a malevolent animistic agent, the shark. The representation of the shark exploits the structure of evolved hazard-precautionary cognitive...

  6. Midgut malrotation presenting with left-sided acute appendicitis and CT inversion sign

    Science.gov (United States)

    Çağlar, Emrah; Arıbaş, Bilgin; Tiken, Ramazan; Keskin, Suat

    2014-01-01

    In patients presenting with abdominal pain, appendicitis is the most common surgical disorder. Appendicitis causing pain in the left lower quadrant is extremely rare and can occur with congenital abnormalities that include true left-sided appendix or as an atypical presentation of right-sided long appendix, which projects into the left lower quadrant. We report a case of a 69-year-old man showing midgut malrotation with acute appendicitis presenting as left lower quadrant abdominal pain. PMID:24682135

  7. Four-quadrant flyback converter for direct audio power amplification

    Energy Technology Data Exchange (ETDEWEB)

    Ljusev, P.; Andersen, Michael A.E.

    2005-07-01

    This paper presents a bidirectional, four-quadrant yback converter for use in direct audio power amplication. When compared to the standard Class-D switching-mode audio power amplier with separate power supply, the proposed four-quadrant flyback converter provides simple and compact solution with high efciency, higher level of integration, lower component count, less board space and eventually lower cost. Both peak and average current-mode control for use with 4Q flyback power converters are described and compared. Integrated magnetics is presented which simplies the construction of the auxiliary power supplies for control biasing and isolated gate drives. The feasibility of the approach is proven on audio power amplier prototype for subwoofer applications. (au)

  8. Jaw locking after maxillofacial trauma

    Directory of Open Access Journals (Sweden)

    David B. Kamadjaja

    2007-09-01

    Full Text Available The purpose of this report is to present two cases of jaw locking with two different etiologies. In case #1, jaw locking occured 5.5 months after a surgical reduction and internal fixation on the fractured maxilla and mandible. Some plain radiographic x-ray were made but failed to give adequate information in establishing the cause of trismus. The three dimensional computed tomography (3D-CT was finally made and able to help guide the pre-operative diagnosis and treatment. Two-steps gap arthroplasty were done comprising a gap arthroplasty leading to acceptable outcome. An adult patient in case #2 with a history of trauma at his childhood and bird-like face apprearance clinically, was unable to open the mouth since the time of accident. The patient was diagnosed with bilateral ankylosis of temporomandibular joints. One side (right gap arthroplasty was done and resulted in normal mouth opening.

  9. JAW CYSTS AND GUIDED BONE REGENERATION (a late complication after enucleation

    Directory of Open Access Journals (Sweden)

    Hristina Lalabonova

    2013-10-01

    Full Text Available Maxillary jaw bone possesses a high regenerative capacity. Yet sometimes the defects enucleation of jaw cysts leaves may regenerate only partially or not at all. For this reason some researchers advise treatment of the residual cavities after cystectomy using bone regeneration stimulation methods. We report a case of an atypical complication after enucleation of a maxillary cyst manifesting itself eight years after the initial treatment. The symptoms the patient reported were at first periodic sweating on the left sides of face and head. This was followed by a piercing pain in the left palpebral fissure radiating to the middle of the palate and felt in the left cheekbone, left eye and left supraorbital ridge. The patient has a history of maxillary cysts recurring three times and of three operations she had 20, 12 and 8 years previously. The multiple recurrences of the cysts after their enucleation indicates poor regenerative capacity of the body which resulted in the formation of cicatricial tissue. It is most probably this tissue that was responsible for the disruption of the nerve conduction capacity which can account for the reported symptoms. We filled the cavity with bone graft material which boosted the bone structure regeneration. Although maxillary jaws possess high regenerative capacity we advise the use of guided bone regeneration in cases of large bone defects that usually occur after enucleation of jaw cysts.

  10. Oncoplastic Surgery for Upper/Upper Inner Quadrant Breast Cancer.

    Science.gov (United States)

    Lin, Joseph; Chen, Dar-Ren; Wang, Yu-Fen; Lai, Hung-Wen

    2016-01-01

    Tumors located in the upper/upper inner quadrant of the breast warrant more attention. A small lesion relative to the size of breast in this location may be resolved by performing a level I oncoplastic technique. However, a wide excision may significantly reduce the overall quality of the breast shape by distorting the visible breast line. From June 2012 to April 2015, 36 patients with breast cancer located in the upper/upper inner quadrant underwent breast-conservation surgery with matrix rotation mammoplasty. According to the size and location of the tumor relative to the nipple-areola complex, 11 patients underwent matrix rotation with periareolar de-epithelialization (donut group) and the other 25 underwent matrix rotation only (non-donut group). The cosmetic results were self-assessed by questionnaires. The average weights of the excised breast lumps in the donut and non-donut groups were 104.1 and 84.5 g, respectively. During the 3-year follow-up period, local recurrence was observed in one case and was managed with nipple-sparing mastectomy followed by breast reconstruction with prosthetic implants. In total, 31 patients (88.6%) ranked their postoperative result as either acceptable or satisfactory. The treated breasts were also self-evaluated by 27 patients (77.1%) to be nearly identical to or just slightly different from the untreated side. Matrix rotation is an easy breast-preserving technique for treating breast cancer located in the upper/upper inner quadrant of the breast that requires a relatively wide excision. With this technique, a larger breast tumor could be removed without compromising the breast appearance.

  11. Oncoplastic Surgery for Upper/Upper Inner Quadrant Breast Cancer.

    Directory of Open Access Journals (Sweden)

    Joseph Lin

    Full Text Available Tumors located in the upper/upper inner quadrant of the breast warrant more attention. A small lesion relative to the size of breast in this location may be resolved by performing a level I oncoplastic technique. However, a wide excision may significantly reduce the overall quality of the breast shape by distorting the visible breast line. From June 2012 to April 2015, 36 patients with breast cancer located in the upper/upper inner quadrant underwent breast-conservation surgery with matrix rotation mammoplasty. According to the size and location of the tumor relative to the nipple-areola complex, 11 patients underwent matrix rotation with periareolar de-epithelialization (donut group and the other 25 underwent matrix rotation only (non-donut group. The cosmetic results were self-assessed by questionnaires. The average weights of the excised breast lumps in the donut and non-donut groups were 104.1 and 84.5 g, respectively. During the 3-year follow-up period, local recurrence was observed in one case and was managed with nipple-sparing mastectomy followed by breast reconstruction with prosthetic implants. In total, 31 patients (88.6% ranked their postoperative result as either acceptable or satisfactory. The treated breasts were also self-evaluated by 27 patients (77.1% to be nearly identical to or just slightly different from the untreated side. Matrix rotation is an easy breast-preserving technique for treating breast cancer located in the upper/upper inner quadrant of the breast that requires a relatively wide excision. With this technique, a larger breast tumor could be removed without compromising the breast appearance.

  12. Israel's Quadrant: Weeping, Laughing, and the Measures of the Stars

    Science.gov (United States)

    Locci, A. A.

    2011-06-01

    In the Jewish culture of the Middle Ages, the astral bodies were constantly given a special attention. They were deeply admired in religious poetry, and studied and observed in scientific and technical works. In an elegy of an anonymous poet of the 11th century, which is usually read in the celebrations of the 9th day of Ab, constellations and stars share the grief for the destruction of the temple of Jerusalem. Like the Israel Tribes, all constellations are said to weep; Pleiades and Orion are said to darken their face, the Scales turn asymmetrical, the pan of death overrides the pan of life; Scorpio is scared and trembles, Sagittarius turns his face back. Jacob ben Machir ibn Tibbon, born in Marseille in 1236, was physician, mathematician, and astronomer. He translated Euclides' Elements, the Treatise of the Armillar Sphere by Qusta ibn Luqa, the Treatise on the Astrolabe by abu al-Kasim Ahmad ibn al Saffar, and works of Ptolemy, Averroes, and Aristoteles. His most important work is the short treatise Rova' Israel ("Israel's Quadrant") which he later translated in Latin with the help of Armengaud from Blaise. In the first chapter, he discusses the Sun risings, the days of the month, the place of the Sun in the sky, and the lunar motion. In the second chapter, he discusses the relations between sunrise and sunset, between moonrise and moonset, and between solar year and lunar month. In the following chapters, he illustrates a technical device which he had developed and which he designates "Israel's Quadrant". This instrument could be used both for the sky and for the Earth, since it allowed to survey and measure the elevation of the stars, the elevation of terrestrial reliefs, and terrestrial horizontal distances. The quadrant is flat, and its area is that of a quarter of a circumference. This instrument was very versatile, it also allowed to calculate hours and time, and this favoured its exceptional diffusion. Thus, its name, "quadrant", was transferred to the

  13. Posterior partially edentulous jaws, planning a rehabilitation with dental implants

    Science.gov (United States)

    Monteiro, Douglas R; Silva, Emily V F; Pellizzer, Eduardo P; Filho, Osvaldo Magro; Goiato, Marcelo C

    2015-01-01

    AIM: To discuss important characteristics of the use of dental implants in posterior quadrants and the rehabilitation planning. METHODS: An electronic search of English articles was conducted on MEDLINE (PubMed) from 1990 up to the period of March 2014. The key terms were dental implants and posterior jaws, dental implants/treatment planning and posterior maxilla, and dental implants/treatment planning and posterior mandible. No exclusion criteria were used for the initial search. Clinical trials, randomized and non randomized studies, classical and comparative studies, multicenter studies, in vitro and in vivo studies, case reports, longitudinal studies and reviews of the literature were included in this review. RESULTS: One hundred and fifty-two articles met the inclusion criteria of treatment planning of dental implants in posterior jaw and were read in their entirety. The selected articles were categorized with respect to their context on space for restoration, anatomic considerations (bone quantity and density), radiographic techniques, implant selection (number, position, diameter and surface), tilted and pterygoid implants, short implants, occlusal considerations, and success rates of implants placed in the posterior region. The results derived from the review process were described under several different topic headings to give readers a clear overview of the literature. In general, it was observed that the use of dental implants in posterior region requires a careful treatment plan. It is important that the practitioner has knowledge about the theme to evaluate the treatment parameters. CONCLUSION: The use of implants to restore the posterior arch presents many challenges and requires a detailed treatment planning. PMID:25610852

  14. Genetics Home Reference: hyperparathyroidism-jaw tumor syndrome

    Science.gov (United States)

    ... Twitter Home Health Conditions Hyperparathyroidism-jaw tumor syndrome Hyperparathyroidism-jaw tumor syndrome Printable PDF Open All Close ... Javascript to view the expand/collapse boxes. Description Hyperparathyroidism-jaw tumor syndrome is a condition characterized by ...

  15. Analyzing surface EMG signals to determine relationship between jaw imbalance and arm strength loss

    Directory of Open Access Journals (Sweden)

    Truong Quang Dang Khoa

    2012-08-01

    Full Text Available Abstract Background This study investigated the relationship between dental occlusion and arm strength; in particular, the imbalance in the jaw can cause loss in arm strength phenomenon. One of the goals of this study was to record the maximum forces that the subjects can resist against the pull-down force on their hands while biting a spacer of adjustable height on the right or left side of the jaw. Then EMG measurement was used to determine the EMG-Force relationship of the jaw, neck and arms muscles. This gave us useful insights on the arms strength loss due to the biomechanical effects of the imbalance in the jaw mechanism. Methods In this study to determine the effects of the imbalance in the jaw to the strength of the arms, we conducted experiments with a pool of 20 healthy subjects of both genders. The subjects were asked to resist a pull down force applied on the contralateral arm while biting on a firm spacer using one side of the jaw. Four different muscles – masseter muscles, deltoid muscles, bicep muscles and trapezoid muscles – were involved. Integrated EMG (iEMG and Higuchi fractal dimension (HFD were used to analyze the EMG signals. Results The results showed that (1 Imbalance in the jaw causes loss of arm strength contra-laterally; (2 The loss is approximately a linear function of the height of the spacers. Moreover, the iEMG showed the intensity of muscle activities decreased when the degrees of jaw imbalance increased (spacer thickness increased. In addition, the tendency of Higuchi fractal dimension decreased for all muscles. Conclusions This finding indicates that muscle fatigue and the decrease in muscle contraction level leads to the loss of arm strength.

  16. Osteosarcoma of the jaw bones.

    Science.gov (United States)

    Chindia, M L

    2001-10-01

    Currently, it has been established that osteosarcoma (OS) of bone is not a stereotyped disease, and several varieties have been identified by clinical findings, radiographic and histopathologic appearances. Generally, it is the most common primary malignant bone neoplasm that accounts for at least 30% of all primary tumours of bone. In the jaw bones, OS accounts for about 4% of all the primary malignant neoplasms. In the general skeleton, the highest incidence is observed in the second decade of life; the neoplasm is said to be unusual before the age of 5 years and very rare after age 50 years. The aetiology and precise pathogenesis of this disease remain unknown. A diagnosis of clinically and radiologically suspicious OS requires meticulous histologic examination. However, histologic diagnosis may also be difficult since the different varieties of OS may have different morphological patterns in different sample sites. Currently, the two therapeutic modalities used in the primary treatment of OS include radical surgery and cytotoxic chemotherapy. In the general skeleton, the use of surgery alone results in a 90% rate of recurrence of OS. Notably, the advent of adjuvant and neoadjuvant cytotoxic chemotherapy as an adjunct to radical surgery has greatly improved the prognosis of many cases of OS of the jaw bones.

  17. Multiple Lesions in the Upper Jaw.

    Science.gov (United States)

    Gedik, R; Gedik, S

    2014-12-01

    Buccal exostoses are benign, broad-based surface masses of the outer or facial aspect of the upper jaw (maxilla) or, less commonly, the lower jaw (mandible). They begin to develop in early adulthood and may very slowly enlarge over years. We report here an adult man with multiple masses of the maxilla above the teeth.

  18. Geological map of Washington: southwest quadrant (digital edition)

    Science.gov (United States)

    Walsh, Timothy J.; Korosec, Michael A.; Phillips, William M.; Logan, Robert L.; Schasse, Henry W.; Digital database by Meagher, Karen L.; Haugerud, Ralph A.

    1999-01-01

    This report comprises digital spatial data that constitute a partial transcription of the 1:250,000-scale Geologic map of Washington - southwest quadrant (Walsh and others, 1987); digital base material, symbolsets, and ARC Macro Language (AML) procedures to create a geologic map on a shaded-relief base from the digital spatial data; and Postscript and RTL plotfiles for such a geologic map. The digital transcription is incomplete: offshore folds and faults, the southern limit of the continental ice sheet in the Puget Lowland, the published base map (Washington Division of Geology and Earth Resources map TM-1), geologic unit correlation diagrams, and most of the explanatory material that accompanies Walsh and others (1987) are not present here.

  19. Four-Quadrant Facial Function in Dysphagic Patients after Stroke and in Healthy Controls

    OpenAIRE

    Mary Hägg; Lita Tibbling

    2014-01-01

    This study aims to examine any motility disturbance in any quadrant of the face other than the quadrant innervated by the lower facial nerve contralateral to the cortical lesion after stroke. Thirty-one stroke-afflicted patients with subjective dysphagia, consecutively referred to a swallowing centre, were investigated with a facial activity test (FAT) in all four facial quadrants and with a swallowing capacity test (SCT). Fifteen healthy adult participants served as FAT controls. Sixteen pat...

  20. Simulation of a low atmospheric-noise modified four-quadrant position sensitive detector

    International Nuclear Information System (INIS)

    Bertilsson, K.; Dubaric, E.; Thungstroem, G.; Nilsson, H.-E.; Petersson, C.S.

    2001-01-01

    A modified four-quadrant position sensitive detector (PSD) is developed. This structure is less sensitive to atmospheric turbulence that is a major drawback with the traditional four-quadrant detector. The inter-electrode resistance is as high as for the four-quadrant detector, which is an advantage compared to the lateral effect PSD. The linearity for the modified four-quadrant detector is good in the whole active range of sensing. The structures are limited to small sensing areas with well focused beams and are suitable for use in detectors up to 1 mm in size

  1. Control of jaw-clenching forces in dentate subjects.

    Science.gov (United States)

    Testa, Marco; Rolando, Mara; Roatta, Silvestro

    2011-01-01

    To characterize the control of jaw-clenching forces by means of a simple force-matching exercise. Seventeen healthy subjects, provided with visual feedback of the exerted force, carried out a unilateral force-matching exercise requiring developing and maintaining for 7 seconds a jaw-clenching force at 10%, 30%, 50%, and 70% of the maximum voluntary contraction. The task was repeated three times in each of two sessions. Motor performance was assessed, for both left and right sides, by different indices quantifying mean distance (MD), offset error (OE), and standard deviation (SD). Their dependence on force intensity, side, and time was assessed by ANOVA. All error indices increased with the intensity of contraction in absolute terms. After normalization with respect to force level, the average performance in the second session was characterized by MD of 8.1% ± 2.6, OE 4.8% ± 2.9, and SD 12.7% ± 6.7 (mean ± standard deviation). Assessment of performance exhibited good reliability for all indices (intraclass correlation coefficient ranging from 74% to 88%). The motor performance improved with repetition (P .05) but was highly correlated between left and right side (P < .01). The adopted approach is adequate to provide for an objective assessment of individual force control, although the presence of a learning phase must be taken into account.

  2. O Quadrante de Ruetsap e a anti-ciência, tecnologia e inovação Ruetsap's Quadrant and anti-science, technology and innovation

    Directory of Open Access Journals (Sweden)

    Francisco Radler de Aquino Neto

    2005-12-01

    Full Text Available The concept of research and the controversy among classical models for C, T & I, outdated by the development of knowledge and Post-modern society needs were revisited through the (3 Quadrants advanced by Donald Stokes in the mid-nineties. The scientific community to fit into these Quadrants was faced with many difficulties and reacted by issuing pseudo-facts, accepted by under-prepared technocrats as viable justifications for conducting research in face of these new paradigms. In a poor country full of contrast and needs such as Brazil, this attitude satisfies the bureaucracy and academic elite, but frustrates government and society, that do not get, in the expected measure, the benefits of their commitment with the Teaching, Research and Extension Sectors mainly embedded in the Public University system. An extension, in fact a contradictory approach, to Pasteur's Quadrant, is proposed to characterize this situation: The Syndrome of Ruetsap's Quadrant.

  3. Evaluation of the association between quantitative mammographic density and breast cancer occurred in different quadrants.

    Science.gov (United States)

    Chan, Siwa; Chen, Jeon-Hor; Li, Shunshan; Chang, Rita; Yeh, Darh-Cherng; Chang, Ruey-Feng; Yeh, Lee-Ren; Kwong, Jessica; Su, Min-Ying

    2017-04-17

    To investigate the relationship between mammographic density measured in four quadrants of a breast with the location of the occurred cancer. One hundred and ten women diagnosed with unilateral breast cancer that could be determined in one specific breast quadrant were retrospectively studied. Women with previous cancer/breast surgery were excluded. The craniocaudal (CC) and mediolateral oblique (MLO) mammography of the contralateral normal breast were used to separate a breast into 4 quadrants: Upper-Outer (UO), Upper-Inner (UI), Lower-Outer (LO), and Lower-Inner (LI). The breast area (BA), dense area (DA), and percent density (PD) in each quadrant were measured by using the fuzzy-C-means segmentation. The BA, DA, and PD were compared between patients who had cancer occurring in different quadrants. The upper-outer quadrant had the highest BA (37 ± 15 cm 2 ) and DA (7.1 ± 2.9 cm 2 ), with PD = 20.0 ± 5.8%. The order of BA and DA in the 4 separated quadrants were: UO > UI > LO > LI, and almost all pair-wise comparisons showed significant differences. For tumor location, 67 women (60.9%) had tumor in UO, 16 (14.5%) in UI, 7 (6.4%) in LO, and 20 (18.2%) in LI quadrant, respectively. The estimated odds and the 95% confidence limits of tumor development in the UO, UI, LO and LI quadrants were 1.56 (1.06, 2.29), 0.17 (0.10, 0.29), 0.07 (0.03, 0.15), and 0.22 (0.14, 0.36), respectively. In these 4 groups of women, the order of quadrant BA and DA were all the same (UO > UI > LO > LI), and there was no significant difference in BA, DA or PD among them (all p > 0.05). Breast cancer was most likely to occur in the UO quadrant, which was also the quadrant with highest BA and DA; but for women with tumors in other quadrants, the density in that quadrant was not the highest. Therefore, there was no direct association between quadrant density and tumor occurrence.

  4. X-ray computed tomography library of shark anatomy and lower jaw surface models.

    Science.gov (United States)

    Kamminga, Pepijn; De Bruin, Paul W; Geleijns, Jacob; Brazeau, Martin D

    2017-04-11

    The cranial diversity of sharks reflects disparate biomechanical adaptations to feeding. In order to be able to investigate and better understand the ecomorphology of extant shark feeding systems, we created a x-ray computed tomography (CT) library of shark cranial anatomy with three-dimensional (3D) lower jaw reconstructions. This is used to examine and quantify lower jaw disparity in extant shark species in a separate study. The library is divided in a dataset comprised of medical CT scans of 122 sharks (Selachimorpha, Chondrichthyes) representing 73 extant species, including digitized morphology of entire shark specimens. This CT dataset and additional data provided by other researchers was used to reconstruct a second dataset containing 3D models of the left lower jaw for 153 individuals representing 94 extant shark species. These datasets form an extensive anatomical record of shark skeletal anatomy, necessary for comparative morphological, biomechanical, ecological and phylogenetic studies.

  5. Focal tracer uptake in the jaw.

    Science.gov (United States)

    El-Zahry, Mai R; Sinzinger, Helmut

    2014-01-01

    Focal tracer uptake in the jaw during conventional bone scintigraphy is a quite frequent finding usually due to dental disease and seldom to other diseases including malignant disease. Methylene diphosphonate-technetium-99m ((99m)Tc-MDP) 3-phase bone scan is considered the most sensitive imaging method for the detection of jaw osteonecrosis at an early stage. This finding can also but seldom be seen in patients undergoing palliative radionuclide treatment for bone metastases. In conclusion, focal jaw lesions are usually benign and of dental origin. In a small percentage of cancer patients of about 4.3%, jaw lesions as diagnosed among 347 cases of various carcinomas may be due to malignancy. Unfortunately, the number of studies is small, most of them are retrospective and few show biopsy results.

  6. Fractures of the Jaw and Midface

    Science.gov (United States)

    ... of the following categories (called the Le Fort classification): I. The fracture extends above the upper jaw ( ... penetrating trauma (such as a knife or gunshot wound). Injuries may range from relatively small hematomas (collections ...

  7. A Family of Four Quadrant DC/DC Converters with Reduced Number of Components

    DEFF Research Database (Denmark)

    Mostaan, Ali; Soltani, Mohsen

    2015-01-01

    A family of four quadrant DC/DC converters is presented in this paper. Compare with existing four quadrant DC/DC converters that have been introduced in literature, the proposed converters have lower number of components. There are two bidirectional switches, two coupled inductors and one capacitor...

  8. Breast ductal carcinoma metastasis to jaw bones: a case report

    Directory of Open Access Journals (Sweden)

    Mahmood Reza AshabYamin

    2014-04-01

    Full Text Available Malignant tumors of the oral cavity which are metastatic are very rare and consist of 1% of malignancies of the oral cavity. Numbness or paresthesia of the lower lip or the chin is the main feature of presence of metastasis in the jaw. Our patient was a 38 year old woman with chief complaint of pain in the right half of her face, jaw and teeth. Her medical history revealed a radical mastectomy with lymphadenectomy in the left breast because of invasive ductal carcinoma grade II/III and stage IIIA (T2N2M0 without distant metastasis, followed by chemotherapy (before and after the surgery and radiotherapy two years ago. Following complementary examinations a malignant bone lesion in particular osteosarcoma was suspected. According to this evidence, possibility of early diagnosis of malignant tumors is very important for dentists and maxillofacial surgeons. Symptoms such as paresthesia of the lip and chin is very helpful in differential diagnosis of metastatic lesions from other similar clinical cases especially in patients with history of malignancies which minimize surgical and mental injuries and increase life expectancy of patients.

  9. Uncommon presentation of potential medication-related osteonecrosis of the jaw.

    Science.gov (United States)

    Kim, Seong-Gon; Kweon, HaeYong; Lee, Suk-Keun

    2016-01-01

    This article presents a patient with potential atypical medication-related osteonecrosis of the jaw and reviews related literatures. A 52-year-old male showed pain in the left buccal area and had numbness on the left lower lip area. He received medications having anti-angiogenic effect for 4 years. He did not receive irradiation of the jaw regions. In histological view, most of the adipocytes were destroyed and disappeared in the scanty vascular marrow tissue, resulting in the replacement of the fatty necrosis with variable sized vacuolated empty spaces. In the immunohistochemistry analysis, the infiltrated macrophages into the marrow stromal tissue were strongly positive for lysozymes. These findings demonstrate that the presented osteonecrosis underwent a chronic and persistent granulomatous inflammatory reaction. We conclude that the present case might have been caused by anti-angiogenic drug abuse, affecting the reduction of the mandibular marrow vascularity and subsequently inducing fatty necrosis and an extensive osteolytic change of the mandible.

  10. Viscoelastic Characterization of Peripapillary Sclera: Material Properties by Quadrant in Rabbit and Monkey Eyes

    Science.gov (United States)

    Downs, J. Crawford; Suh, J-K. Francis; Thomas, Kevin A.; Bellezza, Anthony J.; Burgoyne, Claude F.; Hart, Richard T.

    2009-01-01

    In this report we characterize the viscoelastic material properties of peripapillary sclera from the four quadrants surrounding the optic nerve head in both rabbit and monkey eyes. Scleral tensile specimens harvested from each quadrant were subjected to uniaxial stress relaxation and tensile ramp to failure tests. Linear viscoelastic theory, coupled with a spectral reduced relaxation function, was employed to characterize the viscoelastic properties of the tissues. We detected no differences in the stress-strain curves of specimens from the four quadrants surrounding the optic nerve head (ONH) below a strain of 4 percent in either the rabbit or monkey. While the peripapillary sclera from monkey eyes is significantly stiffer (both instantaneously and in equilibrium) and relaxes more slowly than that from rabbits, we detected no differences in the viscoelastic material properties (tested at strains of 0–1 percent) of sclera from the four quadrants surrounding the ONH within either species group. PMID:12661206

  11. Breastfeeding is early functional jaw orthopedics (an introduction).

    Science.gov (United States)

    Page, D C

    2001-01-01

    Breastfeeding places beneficial orthopedic forces on the jaws, similar to the forces of Functional Jaw Orthopedics--the newest form of orthodontics. To date most breastfeeding benefits have been attributed to the content of mother's milk. The true orthopedic benefits of breastfeeding, suckling, deserve more definitive attention and research. Breastfeeding is early preventive Functional Jaw Orthopedics because breastfeeding forces impact the jaws during a very rapid period of infant jaw growth. Breast suckling aids proper development of the jaws which form the gateway to the human airway. Bottle, pacifier and digit sucking deform jaws and airways. Forward forces of suckling clearly oppose the backward forces of sucking. Dentists who understand the positive impact of forward orthopedic forces on the jaws should support and advocate exclusive breastfeeding for about 6 months.

  12. 21 CFR 872.2060 - Jaw tracking device.

    Science.gov (United States)

    2010-04-01

    ... the diagnosis of temporomandibular joint disorders and associated orofacial pain is a nonpowered or... § 872.9. (b) Jaw tracking device for interpretation of mandibular jaw positions for the diagnosis—(1...

  13. Control strategies for 2-quadrant converter used in grid power flow control

    CERN Document Server

    Maestri, Sebastian; Uicich, Gustavo; Benedetti, Mario; Papastergiou, Konstantinos; Le Godec, Gilles

    2015-01-01

    This work presents the analysis of a two-quadrant regulator connected to the DC-link of a 4-quadrant magnet supply. The key objective is to present some regulation strategies for controlling the peak power required from the power network as well as to recover the magnet energy into capacitor banks. A comparative study that highlights the trade off between the size of reactive elements, and the peak current drawn from the electrical network is presented.

  14. Osteonecrosis of the jaw associated with everolimus: A case report.

    Science.gov (United States)

    Yamamoto, Daigo; Tsubota, Yu; Utsunomiya, Toshiki; Sueoka, Noriko; Ueda, Aiko; Endo, Kayoko; Yoshikawa, Katsuhiro; Kon, Masanori

    2017-02-01

    Everolimus, a mammalian target of rapamycin inhibitor, has recently been approved for the treatment of metastatic estrogen receptor-positive breast cancer, at a daily dose of 10 mg in combination with exemestane. Osteonecrosis of the jaw (ONJ) is a rare but severe condition, characterized by exposed necrotic bone, and is associated with various drugs that are often used to treat advanced malignancies. We herein report the case of a patient with breast cancer who developed ONJ during treatment with everolimus, which improved after discontinuation of the drug. To the best of our knowledge, this is the first reported case of everolimus-associated ONJ in a patient receiving everolimus for metastatic breast cancer. In 2014, an 80-year-old woman was started on treatment with everolimus and exemestane for stage IIB estrogen receptor-positive breast cancer. Within 2 months, the left side of her face became edematous, with localized heat and tenderness of the left mandibular region and a 3-mm round area of exposed bone. There was purulent discharge and the surrounding gingiva was edematous and erythematous. The left mandible exhibited a low signal intensity area on T1-weighted magnetic resonance imaging. Treatment was discontinued and ONJ showed improvement after 2 months. Therefore, when prescribing everolimus for metastatic breast cancer, oncologists should be aware of the possibility of ONJ as a complication.

  15. Multidetector computed tomography of jaw lesions in children and adolescents

    International Nuclear Information System (INIS)

    Gadodia, A.; Seith, A.; Sharma, R.; Choudhury, A.R.; Bhutia, O.; Gupta, A.

    2010-01-01

    Full text: Jaw lesions in paediatric and adolescent population are uncommon and can arise in odontogenic or non-odontogenic tissues. With the advent of multidetector computed tomography (MDCT), algorithm for imaging jaw lesions has changed dramatically. This pictorial essay describes the imaging appearance of commonly encountered jaw lesions in children and adolescents with emphasis on MDCT findings

  16. Effect of different head-neck-jaw postures on cervicocephalic kinesthetic sense

    Science.gov (United States)

    Zafar, Hamayun; Alghadir, Ahmad H.; Iqbal, Zaheen A.

    2017-01-01

    Objectives: To investigate the effect of different induced head-neck-jaw postures on head-neck relocation error among healthy subjects. Methods: 30 healthy adult male subjects participated in this study. Cervicocephalic kinesthetic sense was measured while standing, habitual sitting, habitual sitting with clenched jaw and habitual sitting with forward head posture during right rotation, left rotation, flexion and extension using kinesthetic sensibility test. Results: Head-neck relocation error was least while standing, followed by habitual sitting, habitual sitting with forward head posture and habitual sitting with jaw clenched. However, there was no significant difference in error between different tested postures during all the movements. Conclusions: To the best of our knowledge, this is the first study to see the effect of different induced head-neck-jaw postures on head-neck position sense among healthy subjects. Assuming a posture for a short duration of time doesn’t affect head-neck relocation error in normal healthy subjects. PMID:29199196

  17. Radiologic study of osteomyelitis of the jaw

    International Nuclear Information System (INIS)

    Lee, Young Ho; Ahn, Hyung Kyu

    1980-01-01

    The author studied age and sex distribution, etiology, affected site and several radiographic features of osteomyelitis of the jaw. And radiologic classification of osteomyelitis was also done. The material consisted of 118 males and 96 females examined and/or treated under the diagnosis of osteomyelitis during past 11 years (1970-1980.6) in SNUDH. The obtained results were as followings. 1. The incidence is the highest in teen ages (22.9%) and the lowest in seventies. (2.8%). 2. 199 cases were found in lower jaw, and 15 cases in upper jaw. 30.8% of all cases were located at the posterior portion of mandibular body comprising alveolar region. 3. Radiographic examination of osteolytic lesion revealed that 21.5% of all patients had periapical and alveolar bone rarefaction combined with osteoporotic changes were present at the same time. 4. Sclerotic lesions were seen in 62.2% of all patients and 21.5% of sclerotic lesion were diffuse or homogenous type. 5. Based on the radiologic study, classification of the osteomyelitis of the jaw was made. Localized osteolytic type was the highest in incidence (38.8%) and localized sclerotic type was the lowest (7.0%).

  18. Fractures of the Jaw and Midface

    Science.gov (United States)

    ... diet. More severe fractures (such as those with breaks in more than one place or those in which the ends of the bone are separated, called a displaced fracture) require that the jaw be repaired. Doctors may screw metal plates into the bone on each side ...

  19. Jaw adductor muscles across lepidosaurs: a reappraisal.

    Science.gov (United States)

    Daza, Juan Diego; Diogo, Rui; Johnston, Peter; Abdala, Virginia

    2011-10-01

    The exact homologies of tetrapod jaw muscles remain unresolved, and this provides a barrier for phylogenetic analysis and tracing character evolution. Here, lepidosaur jaw muscles are surveyed using direct examination of species from 23 families and published descriptions of species from 10 families. A revised nomenclature is applied according to proposed homologies with Latimeria. Among lepidosaurs, variation was found in many aspects of jaw muscle anatomy. The superficial layers mm. levator and retractor anguli oris (LAO and RAO) are present in Sphenodon but not all squamates. The external jaw adductor muscles universally present in lepidosaurs are homologous with the main adductor muscle, A2, of Latimeria and include four layers: superficialis (A2-SUP), medialis (A2-M), profundus (A2-PRO), and posterior (A2-PVM). The A2-SUP appears divided in Agamidae, Gekkota, Xantusiidae, and Varanidae. The A2-M is layered lateromedial in lizards but anteroposterior in snakes. The names pseudotemporalis (PS) and pterygomandibularis (PTM) are recommended for subdivisions of the internal adductors of reptiles and amphibians, because the homology of this muscle with the A3' and A3 ″ of Latimeria remains inconclusive. The intramandibularis of lepidosaurs and Latimeria (A-ω) are homologous. The distribution of six jaw muscle characters was found to plot more parsimoniously on phylogenies based on morphological rather than and molecular data. Character mapping indicates that Squamata presents reduction in the divisions of the A2-M, Scincoidea presents reduction or loss of LAO, and two apomorphic features are found for the Gekkota. Copyright © 2011 Wiley-Liss, Inc.

  20. Oral squamous cell carcinoma arising in a patient after hematopoietic stem cell transplantation with bisphosphonate-related osteonecrosis of the jaws.

    Science.gov (United States)

    Arduino, Paolo G; Scully, Crispian; Chiusa, Luigi; Broccoletti, Roberto

    2015-01-01

    A 55-year-old man with a history of acute myeloid leukaemia treated with hematopoietic stem cell transplantation and with a 5-year history of bisphosphonate-related osteonecrosis of the jaws, following 12 cycles of intravenous zoledronic acid therapy, presented in December 2009 with a history of increasingly severe unilateral lower jaw pain. Oral examination revealed, as previously, exposed bone in the left mandible, but also a new exophytic mass on the lower-left buccal mucosa. Biopsy confirmed a diagnosis of oral squamous cell carcinoma. To the best of our knowledge, this is the first report of an oral squamous cell carcinoma that appeared adjacent to an area of osteochemonecrosis.

  1. Psammomatoid juvenile ossifying fibroma of the jaws.

    Science.gov (United States)

    Malathi, N; Radhika, T; Thamizhchelvan, H; Ravindran, C; Ramkumar, S; Giri, Gvv; Gopal, Deepika

    2011-09-01

    Juvenile ossifying fibroma is an uncommon, benign, bone-forming neoplasm with aggressive local growth that is distinguished from other fibro-osseous lesions primarily by its age of onset, clinical presentation and aggressive behavior. Although a benign entity, juvenile ossifying fibroma is known to be locally aggressive and has a high tendency to recur. Two distinctive microscopic patterns have been described: A trabecular variant and a psammomatoid variant. This latter variant is predominantly a craniofacial lesion and occurs rarely in the jaws. We present herein two cases of psammomatoid juvenile ossifying fibroma involving the jaws. The first case was a mandibular lesion in a 31-year-old female whereas the second case presented with maxillary involvement in a 46-year-old female. In addition, the pathology of the lesion was analyzed with confocal laser scanning microscopy.

  2. Solitary peripheral osteomas of the jaws

    OpenAIRE

    de França, Talita Ribeiro Tenório; Gueiros, Luiz Alcino Monteiro; de Castro, Jurema Freire Lisboa; Catunda, Ivson; Leão, Jair Carneiro; da Cruz Perez, Danyel Elias

    2012-01-01

    Osteoma is a benign osteogenic tumor composed of cancellous or compact bone, classified as peripheral, central, or extraskeletal. Peripheral osteomas are uncommon. Excluding the maxillary sinuses, the maxilla is a rare site for osteomas. The purpose of this report was to describe clinicopathological and radiological features of two peripheral osteomas occurring in the jaws, one located in the mandible and another in the edentulous maxillary alveolar ridge. The tumors were asymptomatic and wer...

  3. Osteonecrosis of jaw associated with bisphosphonate use

    Directory of Open Access Journals (Sweden)

    Ashu Rastogi

    2012-01-01

    Full Text Available Bisphosphonates are associated with osteonecrosis of the jaw (ONJ that is defined as an area of exposed, nonvital bone in the maxilla or mandible persisting over 6-8 weeks. We describe a case of 55-year-old female who developed ONJ after tooth extraction and had been receiving oral ibandronate for osteoporosis. Diagnosis of ONJ was confirmed on CT scan. The patient was managed conservatively as she denied teriparatide therapy because of cost constraints.

  4. Osteoid osteoma of jaws: An overview

    Directory of Open Access Journals (Sweden)

    Akhilanand Chaurasia

    2008-01-01

    Full Text Available Osteoid osteoma is a rare benign osteoblastic tumor with distinctive histologic characteristics consisting of a central core of vascular osteoid tissue i.e., nidus surrounded by a peripheral zone of sclerotic bone. Most of cases of Osteoid osteoma are reported in long bones of body, however, their occurrence in jaw bones is extremely rare. The purpose of this article is to present an overview regarding its clinical presentation, diagnosis and management.

  5. Myofibromas of the jaws in children.

    Science.gov (United States)

    Abramowicz, Shelly; Simon, Lisa E; Kozakewich, Harry P; Perez-Atayde, Antonio R; Kaban, Leonard B; Padwa, Bonnie L

    2012-08-01

    Controversy exists as to the most appropriate treatment strategy for myofibromas of the jaws: en bloc resection versus enucleation. The purpose of the present study was to evaluate the treatment outcomes in children with these uncommon benign tumors. We performed a retrospective chart review of pediatric patients with jaw myofibromas. The predictor variables included patient demographics, clinical presentation, imaging characteristics, pathologic features, treatment, and follow-up. The outcome variable was cure or recurrence. The descriptive statistics were computed. A total of 12 patients (mean age 6.7 years) met the inclusion criteria. There were 2 presentations: exophytic soft tissue mass in dentoalveolar segment (n = 5); and intraosseous mass (n = 7). No distinct histopathologic differences were found between the 2 groups. Exophytic myofibromas displayed rapid growth, tooth displacement and/or mobility, bony expansion, and/or cortical thinning/perforation. Most were treated by resection. The intraosseous lesions were asymptomatic and/or incidentally discovered. They were treated by enucleation and curettage. The mean follow-up for the 2 groups was 6.5 and 3.9 years, respectively. There were no recurrences. The results of the present study indicate that there are 2 clinical presentations of myofibromas of the jaws in children: an aggressive exophytic type and a nonaggressive intraosseous type. They are histopathologically indistinguishable. Copyright © 2012 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  6. Cytogenetics of jaw cysts - a pilot study.

    Science.gov (United States)

    Manor, Esther; Brennan, Peter A; Bodner, Lipa

    2012-07-01

    The pathogenesis of cysts that arise in the jaws is still not certain, and the underlying mechanisms of epithelial proliferation are not fully understood. Cysts of the jaw may involve a reactive, inflammatory, or neoplastic process. Cytogenetics, the study of the number and structure of chromosomes, has provided valuable information about the diagnosis, prognosis, and targeted treatment in many cancers, including oral squamous cell carcinoma. Cytogenetics can also provide information about the possible aetiology or neoplastic potential of a lesion, though to our knowledge no studies of this technique have been used for cysts in the jaws. In this pilot study we used cytogenetics in a series of 10 cysts (3 radicular, 4 dentigerous, 2 of the nasopalatine duct, and 1 dermoid). In all cases we found normal karyotypes. Further work and larger numbers are needed for a definitive study, but we can hypothesise from this pilot study that these cysts do not have cytogenetic aberrations and so have no neoplastic potential. Copyright © 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  7. Florid osseous dysplasia of the jaws

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Su Beom; Koh, Kwang Joon [Dept. of Oral Radiology, College of Dentistry, Chonbuk National University, Chonju (Korea, Republic of)

    1995-02-15

    Few cases of florid osseous dysplasia has been described as a condition that characteristically affects the jaws. It usually manifests as multiple radiopaque masses distributed throughout the jaws. Confusion exists about the relationship of florid osseous dysplasia, gigantiform cementoma, chronic sclerosing osteomyelitis, sclerosing osteitis or multiple enostosis. Authors experienced a case of florid osseous dysplasia of the jaws in 52-year-old female on the basis of clinical, radiographic and histopathologic findings. The characteristic features are as follows: 1. In clinical examination, there was no clinical sign and symptoms except extrated area. And there was no facial asymmetry. 2. Radiograms show round or lobular dense radiopaque masses surrounded by radiolucent bands in lower molar teeth area bilaterally. And slight increased radiopacities in maxillary molar teeth area bilaterllay. There was no expansion or thinning of buccal and lingual cortical bones. There is no displacement or resorption of involved teeth. In right side of mandible, mandibular canal is displaced inferiorly due to mass. 3. Photomicrograms show densely mineralized sclerotic acellular masses with empty lacunae. Pattern is suggestive of cementum, although it could be considered sclerotic bone. In the periphery, lesion consisting of moderately cellular fibrous tissue in calcified products are deposited.

  8. Large Signal Model of a Four-quadrant AC to DC Converter for Accelerator Magnets

    CERN Document Server

    De la Calle, R; Rinaldi, L; Völker, F V

    2001-01-01

    This paper presents the large signal model of a four-quadrant AC to DC converter, which is expected to be used in the area of particle accelerators. The system’s first stage is composed of a three-phase boost PWM (Pulse Width Modulated) rectifier with DSP (Digital Signal Processing) based power factor correction (PFC) and output voltage regulation. The second stage is a full-bridge PWM inverter that allows fast four-quadrant operation. The structure is fully reversible, and an additional resistance (brake chopper) is not needed to dissipate the energy when the beam deflection magnet acts as generator.

  9. [Bisphosphonate-associated osteonecrosis of the jaw].

    Science.gov (United States)

    Abu-Id, M H; Açil, Y; Gottschalk, J; Kreusch, T

    2006-03-01

    Bisphosphonates (BP) are widely used in patients with osteoporosis or malignant tumors with bony metastases such as breast cancer and plasmocytoma because of their potency to affect osteoclasts and bone resorption. Osteonecrosis of the jaw (ONJ) has been described as a potential side effect since 2003. After a review of the literature we present results of a questionnaire, which was sent to departments of oral and maxillofacial surgery (OMFS) in German-speaking countries. We present 349 patients from the literature, 54 patients from the departments of OMFS and 19 cases from our own department. These patients ware analyzed depending on their disease, their medication, localization of the affected area, histological signs and therapeutic outcome. Of 73 patients, 68 (93%) were treated with pamidronate or zoledronate; 69 (94%) patients suffered from malignant diseases, 3 (5%) had osteoporosis, and 1 (1%) had Paget's disease. In 57 (78%) patients the ONJ affected the mandible, in 12 (16%) the maxilla and in 4 (5%) both jaws. A previous tooth extraction was reported in 38 (52%) patients, and in 35 (48%) ONJ occurred spontaneously. Histological findings were similar to osteomyelitis with a high number of actinomyces colonies. Nine (12%) patients received non-surgical treatment only, 52 (71%) patients underwent minor surgical procedures (e. g. decortication) and 19 (26%) patients underwent marginal or segmental resection of the jaw. Considering all treatment modalities, healing was achieved in 55; the most effective was marginal and segmental resection (88%). Though millions of patients receive BP treatment only a few suffer from ONJ. The incidence in cancer patients with pamidronate and zoledronate therapy is 4%-10%. Because of the similarity to "phossy jaw", seen in patients dealing with white phosphorus in the nineteenth century, some authors call the new entity "bis-phossy jaw". As the pathogenesis of ONJ is not clear we recommend that the descriptive term

  10. Bisphosphonate-Related Osteonecrosis of the Jaw Mimicking Bone Metastasis

    OpenAIRE

    Bhatt, Geetika; Bhatt, Aashish; Dragun, Anthony E.; Li, Xiao-Feng; Civelek, A. Cahid

    2014-01-01

    Osteonecrosis of the jaw is usually a potential complication of bisphosphonate therapy. In a cancer patient, this disease entity can be misdiagnosed as a metastatic lesion. Our aim is to make clinicians aware of bisphosphonate associated osteonecrosis of the jaw to prevent misdiagnosis and initiate proper treatment at the earliest. We present the case of a breast cancer patient with multiple bony metastases and a jaw lesion presumed to be metastases. After no response to palliative radiation,...

  11. Current radiological strategies for the assessment of right lower quadrant abdominal pain

    Directory of Open Access Journals (Sweden)

    Pumersha Naidoo

    2014-12-01

    Full Text Available Right lower quadrant abdominal pain is a common clinical entity. Imaging and the radiologistplay an integral role in achieving a diagnosis, so guiding prompt management of patients.This review discusses the spectrum of pathology and imaging findings, and highlights and contrasts the preferred imaging modalities in different subsets of patients.

  12. Cultural-Historical Activity Theory/Design-Based Research in Pasteur's Quadrant

    Science.gov (United States)

    Greeno, James G.

    2016-01-01

    About two decades ago, Donald Stokes published "Pasteur's Quadrant" (Stokes, 1997). Stokes proposed that the motivations of different research projects can be understood as a two-dimensional system, with higher or lower concern for improving technology and practice on one dimension and higher or lower concern for improving fundamental…

  13. Budidaya Anggur Laut (Caulerpa Racemosa melalui Media Tanam Rigid Quadrant Nets Berbahan Bambu

    Directory of Open Access Journals (Sweden)

    Gede Ari Yudasmara

    2015-01-01

    Full Text Available Anggur laut (Caulerpa racemosa merupakan makro alga hijau yang sering dimanfaatkan sebagai makanan bagi masyarakat sekitar pantai. Akan tetapi ketersediaannya masih dalam jumlah yang sangat terbatas dan musiman, karena masih tergantung dari alam dan belum dibudidayakan secara baik dan benar. Untuk itu diperlukan usaha budidaya untuk menunjang kontinuitas produksinya. Penelitian ini bertujuan untuk mengkaji dan menganalisis efektifitas dan efisiensi rigid quadrant nets berbahan bambu dalam budidaya Caulerpa racemosa dan mengkaji kualitas dan kuantitas yang diperoleh dari penerapan rigid quadrant nets berbahan bambu dalam budidaya Caulerpa racemosa. Untuk mencapai tujuan tersebut dilakukan melalui penelitian eksperimen dengan rancangan pre test post test control group design. Hasil penelitian menunjukkan bahwa rigid quadrant nets berbahan bambu cukup efektif dan efisien dalam budidaya Caulerpa racemosa, begitupula dari segi kualitas dan kuantitas substrat rigid quadrant nets berbahan bambu cukup baik kualitasnya serta hasil panen sebanyak Bak I sebesar 2340,46 gram, Bak II sebesar 2003,60 gram dan Bak ke III sebesar 2135,5 gram dengan masa penanaman selama 42 hari.

  14. Four quadrant parallel peripheral screw fixation for displaced femoral neck fractures in elderly patients

    Directory of Open Access Journals (Sweden)

    Bhava RJ Satish

    2013-01-01

    Conclusion: Closed reduction and cannulated cancellous screw fixation gives satisfactory functional results in large group of elderly patients. The four quadrant parallel peripheral (FQPP screw fixation technique gives good stability, allows controlled collapse, avoids fixation failure and achieves predictable bone healing in displaced femoral neck fracture in patients ≥50 years of age.

  15. Supporting Document for the SW Quadrant Historical Tank Content Estimate for SX-Tank Farm

    International Nuclear Information System (INIS)

    Brevick, C.H.; Gaddis, L.A.; Johnson, E.D.

    1994-06-01

    This Supporting Document provides historical characterization information gathered on SX-Tank Farm, such as historical waste transfer and level data, tank physical information, temperature data, sampling data, and drywell and liquid observation well data for Historical Tank Content Estimate of the SW Quadrant at the Hanford 200 West Area

  16. Supporting document for the SW Quadrant Historical Tank Content Estimate for U-Tank Farm

    International Nuclear Information System (INIS)

    Brevick, C.H.; Gaddis, L.A.; Johnson, E.D.

    1994-06-01

    This Supporting Document provides historical characterization information gathered on U-Tank Farm, such as historical waste transfer and level data, tank physical information, temperature data, sampling data, and drywell and liquid observation well data for Historical Tank Content Estimate of the SW Quadrant at the Hanford 200 West Area

  17. Morphology and evolution of the jaw suspension in lamniform sharks.

    Science.gov (United States)

    Wilga, C D

    2005-07-01

    The morphology of the jaw suspension and jaw protrusion mechanism in lamniform sharks is described and mapped onto a cladogram to investigate how changes in jaw suspension and protrusion have evolved. This has revealed that several evolutionary modifications in the musculoskeletal apparatus of the jaws have taken place among lamniform sharks. Galeomorph sharks (Carcharhiniformes, Lamniformes, Orectolobiformes, and Heterodontiformes) have paired ethmopalatine ligaments connecting the ethmoid process of the upper jaw to the ethmoid region of the cranium. Basal lamniform sharks also acquired a novel single palatonasal ligament connecting the symphysis of the upper jaw to the cranium mid-ventral to the nasal capsule. Sharks in the family Lamnidae subsequently lost the original paired ethmopalatine ligament while retaining the novel palatonasal ligament. Thus, basal lamniform taxa (Mitsukurina owstoni, Carcharius taurus, Alopias vulpinnis) have increased ligamentous support of the lateral region of the upper jaw while derived species (Lamnidae) have lost this lateral support but gained anterior support. In previous studies the morphology of the jaw suspension has been shown to play a major role in the mechanism of upper jaw protrusion in elasmobranchs. The preorbitalis is the primary muscle effecting upper jaw protrusion in squalean (sister group to galeomorphs) and carcharhiniform (sister group to lamniforms) sharks. The preorbitalis originates from the quadratomandibularis muscle and inserts onto the nasal capsule in squalean and carcharhiniform sharks. Carcharhiniform sharks have evolved a subdivided preorbitalis muscle with the new division inserting near the ethmoid process of the palatoquadrate (upper jaw). Alopid sharks have also independently evolved a partially subdivided preorbitalis with the new division inserting at the base of the ethmoid process and surrounding connective tissue. Lamnid sharks have retained the two preorbitalis divisions but have modified

  18. Tomographic TR-PIV measurement of coherent structure spatial topology utilizing an improved quadrant splitting method

    Science.gov (United States)

    Yang, ShaoQiong; Jiang, Nan

    2012-10-01

    In this paper, we calculated the spatial local-averaged velocity strains along the streamwise direction at four spatial scales according to the concept of spatial local-averaged velocity structure function by using the three-dimensional three-component database of time series of velocity vector field in the turbulent boundary layer measured by tomographic time-resolved particle image velocimetry. An improved quadrant splitting method, based on the spatial local-averaged velocity strains together with a new conditional sampling phase average technique, was introduced as a criterion to detect the coherent structure topology. Furthermore, we used them to detect and extract the spatial topologies of fluctuating velocity and fluctuating vorticity whose center is a strong second-quadrant event (Q2) or a fourth-quadrant event (Q4). Results illustrate that a closer similarity of the multi-scale coherent structures is present in the wall-normal direction, compared to the one in the other two directions. The relationship among such topological coherent structures and Reynolds stress bursting events, as well as the fluctuating vorticity was discussed. When other burst events are surveyed (the first-quadrant event Q1 and the third-quadrant event Q3), a fascinating bursting period circularly occurs: Q4-S-Q2-Q3-Q2-Q1-Q4-S-Q2-Q3-Q2-Q1 in the center of such topological structures along the streamwise direction. In addition, the probability of the Q2 bursting event occurrence is slightly higher than that of the Q4 event occurrence. The spatial instable singularity that almost simultaneously appears together with typical Q2 or Q4 events has been observed, which is the main character of the mutual induction mechanism and vortex auto-generation mechanism explaining how the turbulence is produced and maintained.

  19. [Bisphosphonates and osteonecrosis of the jaw].

    Science.gov (United States)

    Schirmer, I; Peters, H; Reichart, P A; Dürkop, H

    2005-07-01

    Since 2003, reports have been published on necrosis of the jaw bones possibly being associated with the administration of bisphosphonates. Bisphosphonates are highly active inhibitors of osteoclasts which have been used prophylactically or symptomatically in the treatment of plasmocytoma, bone metastasis of malignant disease, tumor-associated hypercalcaemia and in the treatment of osteoporosis. Due to the importance of this side effect of bisphosphonates, we report six cases. Six patients (two women and four men) with a median age of 69 years (range 55-37) were diagnosed with osteonecrosis of the maxilla and/or mandible. These osteonecroses did not react adequately to local treatment and systemic therapy with antibiotics. Four patients suffered from plasmocytoma and two patients had a history of metastasising breast cancer. Besides cytostatic chemotherapies, all patients received bisphosphonates over an extended period. Bisphosphonates are considered an important standard in the treatment of plasmocytoma and bone metastasis due to malignancies. Since 2003, several reports have been published describing patients in whom therapy resistant osteonecrosis of jaw bones occurred either after dental extractions or spontaneously. Until then, unknown side effects of bisphosphonate therapy had been suspected. Since patients with malignant diseases receive cytostatic therapy and a range of other drugs, including bisphosphonates, enhancement of the side effects may be presumed. The probable association of the therapeutic use of bisphosphonates and the occurence of jaw bone necrosis has to be studied in further investigations. Patients receiving bisphosphonates should be followed-up regularly to avoid the occurrence of extended osteonecrotic lesions, which should be diagnosed early and treated adequately.

  20. New insights into dinosaur jaw muscle anatomy.

    Science.gov (United States)

    Holliday, Casey M

    2009-09-01

    Jaw muscles are key components of the head and critical to testing hypotheses of soft-tissue homology, skull function, and evolution. Dinosaurs evolved an extraordinary diversity of cranial forms adapted to a variety of feeding behaviors. However, disparate evolutionary transformations in head shape and function among dinosaurs and their living relatives, birds and crocodylians, impair straightforward reconstructions of muscles, and other important cephalic soft tissues. This study presents the osteological correlates and inferred soft tissue anatomy of the jaw muscles and relevant neurovasculature in the temporal region of the dinosaur head. Hypotheses of jaw muscle homology were tested across a broad range archosaur and sauropsid taxa to more accurately infer muscle attachments in the adductor chambers of non-avian dinosaurs. Many dinosaurs likely possessed m. levator pterygoideus, a trait shared with lepidosaurs but not extant archosaurs. Several major clades of dinosaurs (e.g., Ornithopoda, Ceratopsidae, Sauropoda) eliminated the epipterygoid, thus impacting interpretations of m. pseudotemporalis profundus. M. pseudotemporalis superficialis most likely attached to the caudoventral surface of the laterosphenoid, a trait shared with extant archosaurs. Although mm. adductor mandibulae externus profundus and medialis likely attached to the caudal half of the dorsotemporal fossa and coronoid process, clear osteological correlates separating the individual bellies are rare. Most dinosaur clades possess osteological correlates indicative of a pterygoideus ventralis muscle that attaches to the lateral surface of the mandible, although the muscle may have extended as far as the jugal in some taxa (e.g., hadrosaurs, tyrannosaurs). The cranial and mandibular attachments of mm adductor mandibulae externus superficialis and adductor mandibulae posterior were consistent across all taxa studied. These new data greatly increase the interpretive resolution of head anatomy in

  1. Bisphosphonate complications including osteonecrosis of the jaw.

    Science.gov (United States)

    Mehrotra, Bhoomi; Ruggiero, Salvatore

    2006-01-01

    Bisphosphonate therapy has been incorporated in the standard management of patients with multiple myeloma-related bony disease. Although their efficacy in reducing skeletal related events is important in the supportive management of the myeloma patient, post-marketing experience with this class of agents, particularly the more potent intravenous agents pamidronate and zoledronic acid, have raised cautionary notes regarding the potential side effects of these agents. The focus of this session is to review the risk factors, incidence, prevention strategies and management of bisphosphonate-related osteonecrosis of the jaw. In addition, pathophysiology, incidence and monitoring for renal dysfunction during chronic therapy with these agents are reviewed.

  2. Solitary peripheral osteomas of the jaws.

    Science.gov (United States)

    de França, Talita Ribeiro Tenório; Gueiros, Luiz Alcino Monteiro; de Castro, Jurema Freire Lisboa; Catunda, Ivson; Leão, Jair Carneiro; da Cruz Perez, Danyel Elias

    2012-06-01

    Osteoma is a benign osteogenic tumor composed of cancellous or compact bone, classified as peripheral, central, or extraskeletal. Peripheral osteomas are uncommon. Excluding the maxillary sinuses, the maxilla is a rare site for osteomas. The purpose of this report was to describe clinicopathological and radiological features of two peripheral osteomas occurring in the jaws, one located in the mandible and another in the edentulous maxillary alveolar ridge. The tumors were asymptomatic and were fully excised without any complications or recurrence. The lesions were submitted to histopathological analysis and diagnosed as peripheral osteoma, compact type.

  3. Solitary peripheral osteomas of the jaws

    Energy Technology Data Exchange (ETDEWEB)

    Franca, Talita Ribeiro Tenorio de; Gueiros, Luiz Alcino Monteiro; Castro, Jurema Freire Lisboa de; Leao, Jair Carneiro; Cruz Perez, Danyel Elias da [Oral Pathology Unit, Federal University of Pernambuco, Recife (Brazil); Catunda, Ivson [Hospital Geral de Areas, Recife (Brazil)

    2012-06-15

    Osteoma is a benign osteogenic tumor composed of cancellous or compact bone, classified as peripheral, central, or extraskeletal. Peripheral osteomas are uncommon. Excluding the maxillary sinuses, the maxilla is a rare site for osteomas. The purpose of this report was to describe clinicopathological and radiological features of two peripheral osteomas occurring in the jaws, one located in the mandible and another in the edentulous maxillary alveolar ridge. The tumors were asymptomatic and were fully excised without any complications or recurrence. The lesions were submitted to histopathological analysis and diagnosed as peripheral osteoma, compact type.

  4. A monolateral TMJ replacement under intraoral endoscopic assistance for jaw osteomielitis: a modified approach.

    Science.gov (United States)

    Belli, E; Mici, E; Mazzone, N; Catalfamo, L; Fini, G; Liberatore, G M

    2015-01-01

    Alloplastic replacement has become a valid treatment for TMJ endstage disease. The Alkayat and Bramley pre-auricular approach combined with the submandibular incision are the current surgical approaches for TMJ surgery. The present study shows a modified approach using intraoral endoscopic assistance. A female patient affected by jaw osteomielitis with condylar detachment was treated with total left TMJ alloplastic replacement combined with a right TMJ arthroplasty. No subamandibular incision was performed and, subsequently, the risks for permanent or temporary damage to the marginalis mandibulae nerve and surgical submandibular scar were avoided. Postoperative CT-Scan evidenced a good prosthesis position. No complications occurred after two years of follow-up.

  5. Open-mouth jaw locking in cats: a literature review and use of computed tomography in three cases.

    Science.gov (United States)

    Nutt, Anna E; Anderson, Thomas; Gracis, Margherita; Doran, Ivan; Warren-Smith, Chris; Langley-Hobbs, Sorrel J

    2017-11-01

    Case series summary This report summarises and reviews the published cases of open-mouth jaw locking in cats and describes three further cases. Case 1 was a 5-year-old, 5.3 kg male neutered domestic shorthair cat. CT identified changes consistent with temporomandibular joint (TMJ) dysplasia with osseous degenerative changes, and the cat subsequently underwent bilateral partial zygomectomy with bilateral partial coronoidectomy. Case 2 was a 10-year-old, 6.0 kg male neutered Exotic Shorthair. Aside from a fracture of the left maxillary canine tooth crown and absence of the left maxillary fourth premolar tooth, no abnormalities were found on CT scan. The cat also underwent bilateral partial zygomectomy with bilateral partial coronoidectomy. The third case was a 1-year-old, 4.0 kg male neutered Persian cat. Changes on CT were consistent with bilateral TMJ dysplasia, and the cat underwent staged bilateral partial zygomectomy with bilateral partial coronoidectomy. There was no recurrence of open-mouth jaw locking in any of the cases on long-term follow-up. Relevance and novel information Open-mouth jaw locking has been reported in cats of a wide range of ages, from 1-10 years of age. Cats with all skull types (brachycephalic, mesaticephalic and dolichocephalic) may be affected, but brachycephalic breeds seem to be over-represented. A CT scan with the jaw locked in place is recommended for diagnosis and surgical planning purposes; two of the cases reported here document the first cases of TMJ dysplasia in cats to be definitively diagnosed using CT. Trauma and symphyseal or TMJ laxity may also predispose to development of the condition. Partial coronoidectomy and partial zygomatic arch resection performed alone or in combination are generally successful at preventing recurrence. Bilateral partial zygomectomy with bilateral partial coronoidectomy has not previously been reported as a surgical treatment, and is recommended when open-mouth jaw locking occurs bilaterally.

  6. Bisphosphonate-associated osteonecrosis of the jaws

    Directory of Open Access Journals (Sweden)

    Pankaj Agarwal

    2012-01-01

    Full Text Available Bisphosphonates constitute a group of drugs capable of modulating bone turnover and reduce its remodeling when an excessive resorption occurs. This is why they are indicated in a large group of bone diseases like postmenopausal osteoporosis or osteolysis associated with breast cancer or multiple myeloma. Over the last few years and due to their extensive use, many cases of complications associated with their use have been published. Among the most important possible adverse effects are the oral ones, with the appearance of ulcerations and, especially, osteonecrosis of the jaws associated with this therapy. In this paper, we have analyzed the general characteristics of these drugs and their mechanisms of action as well as the described adverse effects, especially oral and maxillofacial, have been made special reference, regarding the prevention of osteonecrosis of the jaws, heightened by cases described in the medical and odontological literature. The preventive protocol backs up the fundamental role of the odontologist in the effective prevention of this process before, during and after the treatment.

  7. surgical management of aggressive synchronous jaw central giant ...

    African Journals Online (AJOL)

    2012-08-08

    Aug 8, 2012 ... a lymphoma at the initial presentation. There are other lesions that occur in the jaws that contain giant cells within them. These include the aneurysmal ... Endod 2002; 93: 161–166. 8. Harris M. Central giant cell granulomas of the jaws regress with calcitonin therapy. Br J Oral Maxillofac. Surg 1993; 31: ...

  8. case reports treatment of ameloblastoma of the jaws in children

    African Journals Online (AJOL)

    2011-03-01

    Mar 1, 2011 ... SUMMARY. Background: To report the surgical experience on the treatment of ameloblastoma of the jaws in children. Method: This is a prospective study of six children below the age of 16 years with ameloblastoma of the jaws seen at the Maxillofacial Unit of the Department of Surgery, Korle Bu Teaching ...

  9. Treatment of ameloblastoma of the jaws in children | Abdulai ...

    African Journals Online (AJOL)

    Background: To report the surgical experience on the treatment of ameloblastoma of the jaws in children. Method: This is a prospective study of six children below the age of 16 years with ameloblastoma of the jaws seen at the Maxillofacial Unit of the Department of Surgery, Korle Bu Teaching Hospital over a fifteen

  10. Radiologic appearance of primary jaw lesions in children.

    Science.gov (United States)

    Gupta, Malini; Kaste, Sue C; Hopkins, Kenneth P

    2002-03-01

    The jaw (an unusual site of primary tumors in children and adolescents) has lesions often found incidentally by dentists on routine panoramic radiographs or during examination of a child who has swelling or tooth pain. This pictorial seeks to familiarize pediatric radiologists with the radiographic appearance of a variety of primary jaw lesions. We retrospectively searched institutional records for cases of primary jaw lesions in children and adolescents. Jaw lesions were characterized as: I, well-circumscribed radiolucent lesions; II, lesions with mixed or variable appearance; III, poorly circumscribed radiolucent lesions; and IV, radiopaque lesions. Although most oral and maxillofacial lesions in children are benign, a broad spectrum of tumors was identified; lesions may occur in patients with unrelated prior malignancy. Because radiologic studies may identify jaw lesions and direct further care, familiarity with the appearance of these entities is prudent.

  11. Radiologic appearance of primary jaw lesions in children

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Malini; Kaste, Sue C. [Department of Diagnostic Imaging, St. Jude Children' s Research Hospital, Memphis, TN (United States); Hopkins, Kenneth P. [Department of Surgery, Division of Dentistry, St. Jude Children' s Research Hospital, Memphis, TN (United States)

    2002-03-01

    Background: The jaw (an unusual site of primary tumors in children and adolescents) has lesions often found incidentally by dentists on routine panoramic radiographs or during examination of a child who has swelling or tooth pain. Objective: This pictorial seeks to familiarize pediatric radiologists with the radiographic appearance of a variety of primary jaw lesions. Materials and methods: We retrospectively searched institutional records for cases of primary jaw lesions in children and adolescents. Jaw lesions were characterized as: I, well-circumscribed radiolucent lesions; II, lesions with mixed or variable appearance; III, poorly circumscribed radiolucent lesions; and IV, radiopaque lesions. Results: Although most oral and maxillofacial lesions in children are benign, a broad spectrum of tumors was identified; lesions may occur in patients with unrelated prior malignancy. Conclusion: Because radiologic studies may identify jaw lesions and direct further care, familiarity with the appearance of these entities is prudent. (orig.)

  12. Biochemical and mechanical characterization of Nereis worm jaws

    Science.gov (United States)

    Broomell, Christopher C.

    The ultimate goal of biomimetics is to elucidate the design principles governing performance in biological materials and apply them to engineering systems. Successful transfer of these principles will require a thorough understanding of the complex interplay between molecular composition, organization and mechanical properties of the material. This dissertation describes the mechanical and biochemical characterization of jaws from the marine polychaete Nereis virens. Nereid jaws possess remarkable mechanical properties considering their predominantly organic composition. Hardness and stiffness are comparable to human dentin. However, in stark contrast to dentin, in Nereis these properties are achieved without mineralization. The role of metal ions in jaw sclerotization is addressed. In the pristine state, Zn ions are concentrated at the tip and toothed-edge of the jaw and are critical for hardness and modulus; both properties are reduced by ˜70% following Zn removal by treatment with EDTA. Furthermore, metal content in the jaw can be manipulated by soaking Zn-depleted samples in metal solutions; the comparative effects of treatment with alternative transition metals under both dry and hydrated conditions are described. The molecular composition of the jaw is also addressed. Protein comprises ˜90% of the jaw mass; amino acid analysis indicates that histidine is increased in the hardened, Zn-rich tip. The major protein component in Nereid jaw extracts is purified and characterized by partial peptide mapping and isolation of a partial clone from a jaw pulp cDNA library. Nvjp-1 is a 38 kDa glycine- histidine-rich protein and is believed to be the principle structural protein in the hardened jaw tip. The effects of selected environmental factors on Nvjp-1 structure and assembly are described. Transition from low to high pH is accompanied by changes in secondary structure and a significant molecular elongation. Furthermore, exposure to transition metals, notably Zn and

  13. A Four-Quadrant PVDF Transducer for Surface Acoustic Wave Detection

    Directory of Open Access Journals (Sweden)

    Zhi Chen

    2012-08-01

    Full Text Available In this paper, a polyvinylidene fluoride (PVDF piezoelectric transducer was developed to detect laser-induced surface acoustic waves in a SiO2-thin film–Si-substrate structure. In order to solve the problems related to, firstly, the position of the probe, and secondly, the fact that signals at different points cannot be detected simultaneously during the detection process, a four-quadrant surface acoustic wave PVDF transducer was designed and constructed for the purpose of detecting surface acoustic waves excited by a pulse laser line source. The experimental results of the four-quadrant piezoelectric detection in comparison with the commercial nanoindentation technology were consistent, the relative error is 0.56%, and the system eliminates the piezoelectric surface wave detection direction deviation errors, improves the accuracy of the testing system by 1.30%, achieving the acquisition at the same time at different testing positions of the sample.

  14. THE QUADRANTS METHOD TO ESTIMATE QUANTITATIVE VARIABLES IN MANAGEMENT PLANS IN THE AMAZON

    Directory of Open Access Journals (Sweden)

    Gabriel da Silva Oliveira

    2015-12-01

    Full Text Available This work aimed to evaluate the accuracy in estimates of abundance, basal area and commercial volume per hectare, by the quadrants method applied to an area of 1.000 hectares of rain forest in the Amazon. Samples were simulated by random and systematic process with different sample sizes, ranging from 100 to 200 sampling points. The amounts estimated by the samples were compared with the parametric values recorded in the census. In the analysis we considered as the population all trees with diameter at breast height equal to or greater than 40 cm. The quadrants method did not reach the desired level of accuracy for the variables basal area and commercial volume, overestimating the observed values recorded in the census. However, the accuracy of the estimates of abundance, basal area and commercial volume was satisfactory for applying the method in forest inventories for management plans in the Amazon.

  15. Deceptions in localizing extrahepatic right-upper-quadrant abdominal masses by CT

    Energy Technology Data Exchange (ETDEWEB)

    Frick, M.P.; Feinberg, S.B.

    1982-09-01

    Eleven patients with various extrahepatic right-upper-quadrant lesions had findings on computed tomography (CT) that strongly suggested intrahepatic location. Diagnostic uncertainties on CT were caused by the large size of these masses (5-12 cm in diameter) and sparsity of retroperitoneal fat planes. Sonography depicted the true location of these lesions more clearly than CT. The complementary role of sonography is stressed.

  16. The importance of Blumensaat's line morphology for accurate femoral ACL footprint evaluation using the quadrant method.

    Science.gov (United States)

    Yahagi, Yoshiyuki; Iriuchishima, Takanori; Horaguchi, Takashi; Suruga, Makoto; Tokuhashi, Yasuaki; Aizawa, Shin

    2018-02-01

    The purpose of this study was to evaluate the difference in the center position of the ACL footprint based on grid placement using the quadrant method according to the morphological variations of the Blumensaat's line. Fifty-nine non-paired human cadaver knees were used. The ACL was cut in the middle, and the femoral bone was cut at the most proximal point of the femoral notch, and the digital images were evaluated using Image J software. The femoral ACL footprint was periphery outlined and the center position was automatically measured. Following Iriuchishima's classification, the morphology of the Blumensaat's line was classified into straight, small hill, and large hill types. From the images, grid quadrants were placed as: Grid (1) without consideration of hill existence and not including the chondral lesion. Grid (2) without consideration of hill existence and including the chondral lesion. Grid (3) with consideration of hill existence and not including the chondral lesion. Grid (4) with consideration of hill existence and including the chondral lesion. The straight type consisted of 19 knees, the small hill type 13 knees, and the large hill type 27 knees. Depending on the quadrant grid placement, significant center position difference was observed both in the shallow-deep, and high-low direction. When hill existence was considered, the center position of the ACL was significantly changed to a high position. The center position of the ACL footprint exhibited significant differences according to Blumensaat's line morphology. For clinical relevance, when ACL surgery is performed in knees with small or large hill type variations, surgeons should pay close attention to femoral tunnel evaluation and placement, especially when using the quadrant method.

  17. Comparison of Optic Nerve Head Blood Flow Autoregulation among Quadrants Induced by Decreased Ocular Perfusion Pressure during Vitrectomy

    Directory of Open Access Journals (Sweden)

    Ryuya Hashimoto

    2017-01-01

    Full Text Available Purpose. The present study aimed to examine changes in optic nerve head (ONH blood flow autoregulation in 4 quadrants (superior, nasal, inferior, and temporal with decreased ocular perfusion pressure (OPP during vitrectomy in order to determine whether there is a significant difference of autoregulatory capacity in response to OPP decrease at each ONH quadrant. Methods. This study included 24 eyes with an epiretinal membrane or macular hole that underwent vitrectomy at Toho University Sakura Medical Center. Following vitrectomy, the tissue mean blur rate (MBR, which reflects ONH blood flow, was measured. Mean tissue MBRs in the four quadrants were generated automatically in the software analysis report. Measurements were conducted before and 5 and 10 min after intraocular pressure (IOP elevation of approximately 15 mmHg in the subjects without systemic disorders. Results. The baseline tissue MBR of the temporal quadrant was significantly lower than that of the other 3 quadrants (all P<0.05. However, the time courses of tissue MBR in response to OPP decrease were not significantly different among the four quadrants during vitrectomy (P=0.23. Conclusions. There is no significant difference in the autoregulatory capacity of the four ONH quadrants in patients without systemic disorders during vitrectomy.

  18. Right Lower Quadrant Abdominal Pain in a Patient with Prior Ventriculoperitoneal Shunting: Consider the Tip!

    Directory of Open Access Journals (Sweden)

    Petros Charalampoudis

    2012-01-01

    Full Text Available Introduction. Ventriculoperitoneal (VP shunting is the treatment of choice for nonobstructive hydrocephalus. In patients with such a device, right lower quadrant abdominal pain can puzzle the surgeon, posing a differential diagnostic problem among appendicitis, nonsurgical colicky pain, and primary shunt catheter tip infection. Treatment is different in either case. Presentation of Case. We hereby present a case of a young woman with prior ventriculoperitoneal shunt positioning who presented to our department with right lower quadrant abdominal pain. The patient underwent a 24-hour observation including a neurosurgery consult in order to exclude acute appendicitis and VP shunt tip infection. Twenty four hours later, the patient’s symptomatology improved, and she was discharged with the diagnosis of atypical colicky abdominal pain seeking a gastroenterologist consult. Discussion. This case supports that when a patient with prior VP shunting presents with right lower quadrant abdominal pain, differential diagnosis can be tricky for the surgeon. Conclusion. Apart from acute appendicitis, primary or secondary VP catheter tip infection must be considered because the latter can be disastrous.

  19. Central Xanthoma of the Jaw Bones: A Benign Tumor.

    Science.gov (United States)

    Rawal, Yeshwant B; Chandra, Srinivasa R; Hall, James M

    2017-06-01

    Extragnathic xanthomas are seen in the bones or as soft tissue masses. They are often associated with hyperlipidemia and are considered as reactive or metabolic lesions. Only 19 cases of xanthomas of the jaws have been reported so far in the English literature. A total of ten cases of central xanthoma of the jaw bones were identified from the Oral and Maxillofacial Pathology biopsy services of the University of Washington and the Tufts University School of Dental Medicine, between the years 2000-2016. The demographic and clinical information on these cases was tabulated logically on the basis of age, gender, location and presence or absence of symptoms, extragnathic lesions and serum hyperlipidemia. Radiographic and histopathological features were also examined. The findings in these cases were correlated with those available from the previously reported cases. Majority of cases are seen in the second and third decades of life. There is no gender predilection. Jaw lesions presented as solitary radiolucencies with a predilection for the posterior mandible. Unlike maxillary lesions, pain and expansion are inconsistent findings in mandibular lesions. Jaw lesions are not associated with extragnathic bone or soft tissue involvement or a hyperlipidemia. The central xanthoma of the jaws is a unique benign tumor. Histopathologically, many other jaw lesions contain variable numbers of foamy histiocytes. Therefore, a diagnosis of a central xanthoma of the jaws must be made after excluding all other such histiocyte containing lesions. This requires correlation of histopathological findings with clinical and radiographic features.

  20. Multimodality Treatment for Rehabilitation of Adult Orthodontic Patient with Complicated Dental Condition and Jaw Relation

    Directory of Open Access Journals (Sweden)

    Yu-Cheng Liaw

    2008-11-01

    Full Text Available A 50-year-old man with severe malocclusion requested comprehensive oral rehabilitation. He presented with retrognathic mandible, anterior deep bite and a gummy smile in the premaxilla, and tenting occlusal plane with severe buccal crossbite of the left maxillary posterior teeth. Inappropriate fixed prostheses spanned the maxilla and the mandible with a class II jaw relationship. A detailed analysis indicated the need for orthodontic treatment, orthognathic surgery, bone graft at the deficient alveolar ridge for implant surgery and a revision of all prostheses. Over a 2-year-period of management, the patient received anterior osteotomy for intrusion of lower anterior teeth, bilateral sagittal splitting osteotomy for mandible advancement and posterior osteotomy for inward upward repositioning of posterior teeth of the left maxilla to correct major jaw deformities. The deficient alveolar ridge in the premaxilla was augmented by autogenous bone graft harvested during the orthognathic surgery. He sequentially had mini-plate and dental implant as anchorage assisting teeth alignment in the mandible. Two 3-fixture-supported implant prostheses were delivered in the premaxilla and the mandible. The improvement in cosmesis, stability and function through treatment and a 2-year clinical follow-up were considered satisfactory.

  1. Audit on titanium reconstruction of mandibular defects for jaw lesions.

    Science.gov (United States)

    Paul, S Arun; Karthik, A Kaneesh; Chacko, Rabin; Karunya, Whinny

    2014-07-01

    The aim of the study is to audit the titanium reconstruction of jaw defects in benign conditions in Christian Medical College and Hospital, Vellore. A retrospective study of titanium reconstruction of mandibular defects due to jaw lesions at Christian Medical College and Hospital, Vellore, India, between May 2008 and May 2011. Mouth opening, facial symmetry, occlusion, chewing ability, plate exposure and patient satisfaction were used as outcome measures. The three-dimensional titanium plate is a reasonable material for immediate mandible reconstruction after surgical resection of benign jaw pathologies.

  2. Jaw-muscle architecture and mandibular morphology influence relative maximum jaw gapes in the sexually dimorphic Macaca fascicularis.

    Science.gov (United States)

    Terhune, Claire E; Hylander, William L; Vinyard, Christopher J; Taylor, Andrea B

    2015-05-01

    Maximum jaw gape is a performance variable related to feeding and non-feeding oral behaviors, such as canine gape displays, and is influenced by several factors including jaw-muscle fiber architecture, muscle position on the skull, and jaw morphology. Maximum gape, jaw length, and canine height are strongly correlated across catarrhine primates, but relationships between gape and other aspects of masticatory apparatus morphology are less clear. We examine the effects of jaw-adductor fiber architecture, jaw-muscle leverage, and jaw form on gape in an intraspecific sample of sexually dimorphic crab-eating macaques (Macaca fascicularis). As M. fascicularis males have relatively larger maximum gapes than females, we predict that males will have muscle and jaw morphologies that facilitate large gape, but these morphologies may come at some expense to bite force. Male crab-eating macaques have relatively longer jaw-muscle fibers, masseters with decreased leverage, and temporomandibular joint morphologies that facilitate the production of wide gapes. Because relative canine height is correlated with maximum gape in catarrhines, and males have relatively longer canines than females, these results support the hypothesis that male M. fascicularis have experienced selection to increase maximum gape. The sexes do not differ in relative masseter physiologic cross-sectional area (PCSA), but males compensate for a potential trade-off between muscle excursion versus muscle force with increased temporalis weight and PCSA. This musculoskeletal configuration is likely functionally significant for behaviors involving aggressive canine biting and displays in male M. fascicularis and provides additional evidence supporting the multifactorial nature of the catarrhine masticatory apparatus. Our results have implications for the evolution of craniofacial morphology in catarrhine primates and reinforce the importance of evaluating additional factors other than feeding behavior and diet

  3. SU-E-T-346: Effect of Jaw Position On Dose to Critical Structures in 3-D Conformal Radiotherapy Treatment of Pancreatic Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Paudel, N; Han, E; Liang, X; Morrill, S; Zhang, X; Hardee, M; Penagaricano, J; Ratanatharathorn, V [Vaneerat, University of Arkansas for Medical Sciences, Little Rock, AR (United States)

    2015-06-15

    Purpose: Three-dimensional conformal therapy remains a valid and widely used modality for pancreatic radiotherapy treatment. It usually meets dose constraints on critical structures. However, careful positioning of collimation jaws can reduce dose to the critical structures. Here we investigate the dosimetric effect of jaw position in MLC-based 3-D conformal treatment planning on critical structures. Methods: We retrospectively selected seven pancreatic cancer patients treated with 3-D conformal radiotherapy. We started with treatment plans (Varian Truebeam LINAC, Eclipse TPS, AAA, 18MV) having both x and y jaws aligned with the farthest extent of the block outline (8mm around PTV). Then we subsequently moved either both x-jaws or all x and y jaws outwards upto 3 cm in 1 cm increments and investigated their effect on average and maximum dose to neighboring critical structures keeping the same coverage to treatment volume. Results: Lateral displacement of both x-jaws by 1cm each increased kidney and spleen mean dose by as much as 1.7% and 1.3% respectively and superior inferior displacement increased liver, right kidney, stomach and spleen dose by as much as 2.1%, 2%, 5.2% and 1.6% respectively. Displacement of all x and y-jaws away by 1cm increased the mean dose to liver, right kidney, left kidney, bowels, cord, stomach and spleen by as much as 4.9%, 5.9%, 2.1%, 2.8%, 7.4%, 10.4% and 4.2% respectively. Percentage increase in mean dose due to 2 and 3cm jaw displacement increased almost linearly with the displaced distance. Changes in maximum dose were much smaller (mostly negligible) than the changes in mean dose. Conclusion: Collimation jaw position affects dose mostly to critical structures adjacent to it. Though treatment plans with MLCs conforming the block margin usually meet dose constraints to critical structures, keeping jaws all the way in, to the edge of the block reduces dose to the critical structures during radiation treatment.

  4. Candidate selection for quadrant-based focal ablation through a combination of diffusion-weighted magnetic resonance imaging and prostate biopsy.

    Science.gov (United States)

    Matsuoka, Yoh; Numao, Noboru; Saito, Kazutaka; Tanaka, Hiroshi; Kumagai, Jiro; Yoshida, Soichiro; Ishioka, Junichiro; Koga, Fumitaka; Masuda, Hitoshi; Kawakami, Satoru; Fujii, Yasuhisa; Kihara, Kazunori

    2016-01-01

    To identify prostatic quadrants that could be preserved without intervention, using diffusion-weighted magnetic resonance imaging (DWI) and extended core biopsy, as a step toward implementation of quadrant-based focal ablation with potential preservation of erectile and ejaculatory functions, based on comparisons with unilateral hemi-gland ablation. We conducted a prebiopsy DWI study including 648 quadrants in 162 men who underwent 14-core biopsy including anterior sampling and radical prostatectomy (RP) for localised cancer. Imaging and pathology were analysed on a quadrant basis. Each quadrant was assessed through four-core sampling. Predictive performance of DWI and biopsy for quadrant status was analysed. On RP specimens, 170 anterior (52.5%) and 172 posterior quadrants (53.1%) harboured significant cancer. Negative predictive values of DWI, biopsy, and their combination for significant cancer were 79.7%, 70.6%, and 91.1%, respectively, in anterior quadrants, and 78.5%, 81.3%, and 91.7%, respectively, in posterior quadrants. DWI incrementally improved the negative predictive values of biopsy in anterior (P < 0.001) and posterior quadrants (P = 0.025), without untoward impacts on positive predictive values. Negative findings on both DWI and biopsy were identified in posterior quadrants of 109 sides (33.6%), but in entire hemi-glands of 54 sides (16.7%). The combination of DWI and 14-core biopsy including anterior sampling efficiently identifies quadrants without significant cancer in men with localised prostate cancer; the remaining quadrants, therefore, could be potential candidate areas for focal ablation. Focal therapy designed based on quadrant-based assessment could be superior to unilateral hemi-gland ablation for preservation of posterior quadrants and retaining of sexual function in more sides. © 2014 The Authors BJU International © 2014 BJU International Published by John Wiley & Sons Ltd.

  5. Central xanthoma of the jaws: a clinicopathologic entity?

    Science.gov (United States)

    Daley, Tom; Dunn, Genevieve; Darling, Mark R

    2015-01-01

    To investigate central lesions of the jaws dominated by foamy macrophages (foam cells), which are interpreted to be "central xanthomas of the jaws" and to differentiate this condition from reported cases of jaw nonossifying fibroma/fibrous cortical defect and benign fibrous histiocytoma of bone. The study is a literature review and a retrospective analysis of clinical, radiographic, microscopic, and immunohistochemical features of five new cases of this condition. The lesion has a predilection for the mandible in adults of variable ages, with the potential to become very large and destructive; however, it has a very low recurrence rate, if any, following surgical curettage. We suggest that the "central xanthoma of the jaws" be considered a unique, although rare, clinicopathologic entity. It is unclear whether this lesion is a benign neoplastic process or a persistent reactive process. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Bisphosphonate-Related Osteonecrosis of the Jaw Mimicking Bone Metastasis

    Directory of Open Access Journals (Sweden)

    Geetika Bhatt

    2014-01-01

    Full Text Available Osteonecrosis of the jaw is usually a potential complication of bisphosphonate therapy. In a cancer patient, this disease entity can be misdiagnosed as a metastatic lesion. Our aim is to make clinicians aware of bisphosphonate associated osteonecrosis of the jaw to prevent misdiagnosis and initiate proper treatment at the earliest. We present the case of a breast cancer patient with multiple bony metastases and a jaw lesion presumed to be metastases. After no response to palliative radiation, repeat radiological imaging studies revealed osteonecrosis of the jaw. Correlating a patient’s clinical information with findings on diagnostic imaging studies, such as SPECT bone and CT scans, can help identify this potential complication of bisphosphonate treatment. Early diagnosis helps minimize unnecessary biopsies and allows for the proper treatment to be instituted.

  7. Bisphosphonate-related osteonecrosis of the jaw mimicking bone metastasis.

    Science.gov (United States)

    Bhatt, Geetika; Bhatt, Aashish; Dragun, Anthony E; Li, Xiao-Feng; Civelek, A Cahid

    2014-01-01

    Osteonecrosis of the jaw is usually a potential complication of bisphosphonate therapy. In a cancer patient, this disease entity can be misdiagnosed as a metastatic lesion. Our aim is to make clinicians aware of bisphosphonate associated osteonecrosis of the jaw to prevent misdiagnosis and initiate proper treatment at the earliest. We present the case of a breast cancer patient with multiple bony metastases and a jaw lesion presumed to be metastases. After no response to palliative radiation, repeat radiological imaging studies revealed osteonecrosis of the jaw. Correlating a patient's clinical information with findings on diagnostic imaging studies, such as SPECT bone and CT scans, can help identify this potential complication of bisphosphonate treatment. Early diagnosis helps minimize unnecessary biopsies and allows for the proper treatment to be instituted.

  8. Multiple myeloma of the jaw: A case report

    Directory of Open Access Journals (Sweden)

    Shubhasini A Raghavan

    2014-01-01

    Full Text Available Multiple myeloma is a systemic B-cell lymphoproliferative disease that causes osteolytic lesions in the vertebra, ribs, pelvic bone, skull and jaw. Rarely jaw lesions are seen as the first sign in multiple myeloma. This is a case report with follow up of a 57-year-old female patient, previously treated for osteoporosis, who presented with a swelling of the jaw. On radiographic examination, she was found to have osteolytic lesions in the mandible and skull bones. These conventional aids led to the diagnosis of multiple myeloma thereby proving that the osteoporotic lesions were a part of the spectrum of multiple myeloma. The patient underwent chemotherapy and is currently on follow-up. This case report emphasizes the importance of early diagnosis of multiple myeloma in the jaw using readily available technologies and illustrates the contribution that oral assessment can provide.

  9. Monte Carlo-based simulation of dynamic jaws tomotherapy

    International Nuclear Information System (INIS)

    Sterpin, E.; Chen, Y.; Chen, Q.; Lu, W.; Mackie, T. R.; Vynckier, S.

    2011-01-01

    Purpose: Original TomoTherapy systems may involve a trade-off between conformity and treatment speed, the user being limited to three slice widths (1.0, 2.5, and 5.0 cm). This could be overcome by allowing the jaws to define arbitrary fields, including very small slice widths (<1 cm), which are challenging for a beam model. The aim of this work was to incorporate the dynamic jaws feature into a Monte Carlo (MC) model called TomoPen, based on the MC code PENELOPE, previously validated for the original TomoTherapy system. Methods: To keep the general structure of TomoPen and its efficiency, the simulation strategy introduces several techniques: (1) weight modifiers to account for any jaw settings using only the 5 cm phase-space file; (2) a simplified MC based model called FastStatic to compute the modifiers faster than pure MC; (3) actual simulation of dynamic jaws. Weight modifiers computed with both FastStatic and pure MC were compared. Dynamic jaws simulations were compared with the convolution/superposition (C/S) of TomoTherapy in the ''cheese'' phantom for a plan with two targets longitudinally separated by a gap of 3 cm. Optimization was performed in two modes: asymmetric jaws-constant couch speed (''running start stop,'' RSS) and symmetric jaws-variable couch speed (''symmetric running start stop,'' SRSS). Measurements with EDR2 films were also performed for RSS for the formal validation of TomoPen with dynamic jaws. Results: Weight modifiers computed with FastStatic were equivalent to pure MC within statistical uncertainties (0.5% for three standard deviations). Excellent agreement was achieved between TomoPen and C/S for both asymmetric jaw opening/constant couch speed and symmetric jaw opening/variable couch speed, with deviations well within 2%/2 mm. For RSS procedure, agreement between C/S and measurements was within 2%/2 mm for 95% of the points and 3%/3 mm for 98% of the points, where dose is greater than 30% of the prescription dose (gamma analysis

  10. Central Xanthoma of the Jaw Bones: A Benign Tumor

    OpenAIRE

    Rawal, Yeshwant B.; Chandra, Srinivasa R.; Hall, James M.

    2016-01-01

    Extragnathic xanthomas are seen in the bones or as soft tissue masses. They are often associated with hyperlipidemia and are considered as reactive or metabolic lesions. Only 19 cases of xanthomas of the jaws have been reported so far in the English literature. A total of ten cases of central xanthoma of the jaw bones were identified from the Oral and Maxillofacial Pathology biopsy services of the University of Washington and the Tufts University School of Dental Medicine, between the years 2...

  11. Evolutionary Trends in the Jaw Adductor Mechanics of Ornithischian Dinosaurs.

    Science.gov (United States)

    Nabavizadeh, Ali

    2016-03-01

    Jaw mechanics in ornithischian dinosaurs have been widely studied for well over a century. Most of these studies, however, use only one or few taxa within a given ornithischian clade as a model for feeding mechanics across the entire clade. In this study, mandibular mechanical advantages among 52 ornithischian genera spanning all subclades are calculated using 2D lever arm methods. These lever arm calculations estimate the effect of jaw shape and difference in adductor muscle line of action on relative bite forces along the jaw. Results show major instances of overlap between taxa in tooth positions at which there was highest mechanical advantage. A relatively low bite force is seen across the tooth row among thyreophorans (e.g., stegosaurs and ankylosaurs), with variation among taxa. A convergent transition occurs from a more evenly distributed bite force along the jaw in basal ornithopods and basal marginocephalians to a strong distal bite force in hadrosaurids and ceratopsids, respectively. Accordingly, adductor muscle vector angles show repeated trends from a mid-range caudodorsal orientation in basal ornithischians to a decrease in vector angles indicating more caudally oriented jaw movements in derived taxa (e.g., derived thyreophorans, basal ornithopods, lambeosaurines, pachycephalosaurs, and derived ceratopsids). Analyses of hypothetical jaw morphologies were also performed, indicating that both the coronoid process and lowered jaw joint increase moment arm length therefore increasing mechanical advantage of the jaw apparatus. Adaptive trends in craniomandibular anatomy show that ornithischians evolved more complex feeding apparatuses within different clades as well as morphological convergences between clades. © 2016 Wiley Periodicals, Inc.

  12. The feasibility of immediately loading dental implants in edentulous jaws

    OpenAIRE

    Henningsen, Anders; Smeets, Ralf; Wahidi, Aria; Kluwe, Lan; Kornmann, Frank; Heiland, Max; Gerlach, Till

    2016-01-01

    Purpose Immediate loading of dental implants has been proved to be feasible in partially edentulous jaws. The purpose of this retrospective investigation was to assess the feasibility of immediately loading dental implants in fully edentulous jaws. Methods A total of 24 patients aged between 53 and 89 years received a total of 154 implants in their edentulous maxillae or mandibles. Among the implants, 45 were set in fresh extracted sockets and 109 in consolidated alveolar bones. The implants ...

  13. Oncoplastic surgery for inner quadrant breast cancer: fish-hook incision rotation flap.

    Science.gov (United States)

    Lee, Seokwon; Lee, Jeeyeon; Jung, Younglae; Bae, Youngtae

    2017-10-01

    In oncoplastic breast surgery, the size and location of the defect are two of the major factors affecting the post-operative cosmetic outcome after partial mastectomy. We introduce a modified superior-based dermoglandular rotation flap technique, which can be applied for relatively large tumours and in cases of inner quadrant defects of the breast without surgery of the contralateral breast. Between January 2007 and December 2012, a total of 34 female patients with breast cancer underwent breast-conserving surgery using the 'fish-hook incision rotational flap'. A fish-hook-shaped skin incision line was designed from an axillary site to the tumour, about 2-3 cm below the skin crease of the inframammary fold. After partial mastectomy, a superior-based dermoglandular tissue flap was mobilized off the pectoralis major muscle and the lower abdominal flap was dissected downward. The dermoglandular flap was then rotated and the lower dissected lower abdominal flap was advanced in the upward direction to fill the defect and restore the breast shape. The cosmetic results were self-estimated 12 months after surgery. Mean excised volume of the breast was 23.2 ± 6.1%. The location of the tumours was as follows: upper inner (n = 13, 38.2%) and lower inner quadrant (n = 21, 61.8%). The overall cosmetic satisfaction was self-estimated as follows: excellent (n = 19, 55.9%); good (n = 10, 29.4%); fair (n = 4, 11.8%); poor (n = 1, 2.9%). The 'fish-hook incision rotation flap' is a feasible, effective oncoplastic technique that can be applicable to a relatively large defect located in the inner quadrant of the breast. © 2015 Royal Australasian College of Surgeons.

  14. Mast Quadrant-assisted Minimally Invasive Modified Transforaminal Lumbar Interbody Fusion: Single Incision Versus Double Incision

    Directory of Open Access Journals (Sweden)

    Xin-Lei Xia

    2015-01-01

    Full Text Available Background: The concept of minimally invasive techniques is to make every effort to reduce tissue damage. Certainly, reducing skin incision is an important part of these techniques. This study aimed to investigate the clinical feasibility of Mast Quadrant-assisted modified transforaminal lumbar interbody fusion (TLIF with a small single posterior median incision. Methods: During the period of March 2011 to March 2012, 34 patients with single-segment degenerative lumbar disease underwent the minimally invasive modified TLIF assisted by Mast Quadrant with a small single posterior median incision (single incision group. The cases in this group were compared to 37 patients with single-segment degenerative lumbar disease in the double incision group. The perioperative conditions of patients in these two groups were statistically analyzed and compared. The Oswestry Disability Index (ODI scores, Visual Analog Scale (VAS scores, and sacrospinalis muscle damage evaluation indicators before operation and 3, 12 months postoperation were compared. Results: A total of 31 and 35 cases in the single incision and double incision groups, respectively, completed at least 12 months of systemic follow-up. The differences in perioperative conditions between the two groups were not statistically significant. The incision length of the single incision group was significantly shorter than that of the double incision group (P < 0.01. The ODI and VAS scores of patients in both groups improved significantly at 3 and 12 months postoperation. However, these two indicators at 3 and 12 months postoperation and the sacrospinalis muscle damage evaluation indicators at 3 months postoperation did not differ significantly between the two groups (P ≥ 0.05. Conclusions: Mast Quadrant-assisted modified TLIF with a small single posterior median incision has excellent clinical feasibility compared to minimally invasive TLIF with a double paramedian incision.

  15. The diagnostic role of US in patients with right lower quadrant abdominal pain

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sheen Woo; Lee, Jeong Kyong; Baek, Seung Yon; Kang, Byung Chul; Lee, Sun Wha [Ewha Womans Univ. College of Medicine, Seoul (Korea, Republic of)

    2000-12-01

    To determine the frequency with which ultrasonography (US) provides a correct diagnosis and suggests appropriate guidance for the treatment of patients with right lower quadrant abdominal pain. During an 11-month period, US was consecutively performed in 84 patients who were presented with right lower quadrant abdominal pain. In the 76 [M:F = 16:60, age range 14-87 (mean, 41) years] who formed the study population, final diagnoses were made surgically or clinically. For US, a 5-7-MHz convex-array, 4-MHz vector-array, and/or 7-MHz linear-array transducer was used, according to the patient's body habitus. To determine how often our US reports had provided a correct diagnosis and suggested appropriate guidance for surgical or medical treatment, and to calculate their diagnostic value, the reports were retrospectively compared with final diagnoses. US diagnoses were acute appendicitis in 40 patients (53%), diseases other than this in 25 patients (33%), and no abnormality in 11 (14%). In 38 of the 40 patients (95%), the diagnosis of acute appendicitis was surgically confirmed as correct, and for other diseases, diagnoses based on the findings of US proved to be correct in 21 of 25 patients (84%). Overall, diagnoses was correct in 67 (88%). As regards appropriate guidance for treatment, 46 (61%) and 30 (39%) patients were diagnosed by US to have surgical and medical diseases, respectively. In 44 of the 46 (96%), it was confirmed guidance was appropriate, and for the 30 with medical disease, this was so in all but one case (97%). Overall, the treatment plan was appropriate in 72 patients (95%). Our study revealed that US was able to provide a correct diagnosis in 88% of patients with right lower quadrant abdominal pain, and in 95% of these, the treatment plan suggested was appropriate. US is, therefore, a valuable screening tool in the diagnosis and therapeutic guidance of such patients.

  16. Historical tank content estimate for the southwest quadrant of the Hanford 200 west area

    Energy Technology Data Exchange (ETDEWEB)

    Brevick, C.H.; Stroup, J.L.; Funk, J.W., Fluor Daniel Hanford

    1997-03-06

    The Historical Tank Content Estimate for the Quadrant provides historical information on a tank-by-tank basis of the radioactive mixed wastes stored in the underground single-shell tanks for the Hanford 200 West Area. This report summarized historical information such as waste history, level history, temperature history, riser configuration, tank integrity, and inventory estimates on a tank- by-tank basis. Tank farm aerial photographs and interior tank montages are also provided for each tank. A description of the development of data for the document of the inventory estimates provided by Los Alamos National Laboratory are also given in this report.

  17. The large-scale distribution of molecular gas in the first Galactic quadrant

    Science.gov (United States)

    Clemens, Dan P.; Sanders, David B.; Scoville, Nicholas Z.

    1988-01-01

    The emission parameters for the molecular component of the interstellar medium are determined throughout the first Galactic quadrant. Face-on maps of the peak midplane molecular density, scale height, and offset from b = 0 deg with roughly 300 pc resolution are presented. These maps are compared with the distribution of cataloged H II regions to test whether both species trace the same Galactic locations. The properties of the spiral (or ringlike) arms are deduced from the derived images and pitch-angle upper limits are estimated. The H II regions are strongly correlated with the dense molecular rings.

  18. A Quadrant Analysis on the Effectiveness of Planning and Control in Urban Housing Development in Selangor

    Directory of Open Access Journals (Sweden)

    Hamizah Yakob

    2016-01-01

    Full Text Available The current planning mechanisms which are development plan and planning control were recognised as important tools in housing planning process. However, the weaknesses involved in the preparation of development plans and its implementation through development control may impose constraints on housing development. The objective of this paper is to evaluate whether the housing planning and control activities practiced require improvement in terms of the level of effectiveness of its implementation by the LPAs and PCs in Selangor using Quadrant Analysis. It was found that three activities; location, compliance and difficulties need high attention to achieve effective housing planning control.

  19. A CLASS OF DISTRIBUTION-FREE TESTS FOR INDEPENDENCE AGAINST POSITIVE QUADRANT DEPENDENCE

    Directory of Open Access Journals (Sweden)

    Parameshwar V Pandit

    2014-02-01

    Full Text Available A class of distribution-free tests based on convex combination of two U-statistics is considered for testing independence against positive quadrant dependence. The class of tests proposed by Kochar and Gupta (1987 and Kendall’s test are members of the proposed class. The performance of the proposed class is evaluated in terms of Pitman asymptotic relative efficiency for Block- Basu (1974 model and Woodworth family of distributions. It has been observed that some members of the class perform better than the existing tests in the literature.  Unbiasedness and consistency of the proposed class of tests have been established.

  20. Four-quadrant propeller modeling: A low-order harmonic approximation

    Digital Repository Service at National Institute of Oceanography (India)

    Haeusler, A.J.; Saccon, A.; Hauser, J.; Pascoal, A.M.; Aguiar, A.P.

    ◦. ✷ 2. THE SIMPLIFIED FOUR-QUADRANT MODEL BY HEALEY ET AL. The key motivation for the work reported here stems from our interest in developing algorithms for the computation of energy-optimal trajectories for multiple vehicles acting in cooperation... in (Oosterveld, 1970, p. 42) or (Smogeli, 2006, Sec. 2.1.2) into (15), all models can be compared against each other and the ideal efficiency. Fig. 6 shows clearly how, using the simple L-model approxima- tion (motivated by the H-model approximation...

  1. 73-year-old woman with abdominal pain in the right lower quadrant

    International Nuclear Information System (INIS)

    Bond, J.R.

    1987-01-01

    A 73-year-old woman presented with a six-day history of abdominal pain that had started in the epigastrium, but recently had become more intense in the right lower quadrant. Peptic ulcer had been diagnosed three years prior to presentation and had been managed medically. On physical examination, epigastric tenderness as well as guarding and rebound tenderness in the right lower quandrant were present. Mild leukocytosis was reported. Computed tomography demonstrated a 5-cm retrocecal mass with low attenuation (fluid content) surrounded by an irregularly thickened uncalcified wall. Multiple areas of tissue debris were seen extending into the mass, but no true separation was present

  2. A study of biological chemistry on the nature of jaw cysts. On the maintainance of homoeostasis in jaw cyst fluid.

    Science.gov (United States)

    Suzuki, M

    1975-06-01

    Jaw cyst lining cells have an active transporting mechanism for Na+ ion and K+ion, a secreting mechanism and a selecting mechanism, and they allow permeation of electrolytes, lipids and protein into cysts. The components within the cysts have a controlling metabolism, and keep the system stable. Tumour wall cells of cystic ameloblastoma have only a passive transporting mechanism for various substances. Their nature differs from that of jaw cyst lining cells.

  3. THERE ARE NO STARLESS MASSIVE PROTO-CLUSTERS IN THE FIRST QUADRANT OF THE GALAXY

    Energy Technology Data Exchange (ETDEWEB)

    Ginsburg, A.; Bally, J.; Battersby, C. [Center for Astrophysics and Space Astronomy, University of Colorado, Boulder, CO 80309 (United States); Bressert, E. [European Southern Observatory, Karl Schwarzschild str. 2, D-85748 Garching bei Muenchen (Germany)

    2012-10-20

    We search the {lambda} = 1.1 mm Bolocam Galactic Plane Survey for clumps containing sufficient mass to form {approx}10{sup 4} M{sub Sun} star clusters. Eighteen candidate massive proto-clusters are identified in the first Galactic quadrant outside of the central kiloparsec. This sample is complete to clumps with mass M{sub clump} > 10{sup 4} M{sub Sun} and radius r {approx}< 2.5 pc. The overall Galactic massive cluster formation rate is CFR(M{sub cluster} > 10{sup 4}) {approx}<5 Myr{sup -1}, which is in agreement with the rates inferred from Galactic open clusters and M31 massive clusters. We find that all massive proto-clusters in the first quadrant are actively forming massive stars and place an upper limit of {tau}{sub starless} < 0.5 Myr on the lifetime of the starless phase of massive cluster formation. If massive clusters go through a starless phase with all of their mass in a single clump, the lifetime of this phase is very short.

  4. A Clinical Observation of Ultrasonographic Diagnosis on Right upper Quadrant Pain

    International Nuclear Information System (INIS)

    Lee, Suck Hong; Moon, T. Y.; Chang, H. Y.; Kim, B. S.

    1982-01-01

    The author analyzed a total of 127 cases of ultrasonography studied for evaluation of the causes of right upper quadrant pain during ten months from Feb.1 to Nov. 30 1981, at the department of radiology, Busan national university and St. Benedict hospital. The results were as follows: 1. ultrasonographic findings of the total of 127 cases are normal in 41(32.3%) cases, and abnormal in 86(67.6%) cases. 2. Clinical diagnosis of normal ultrasonographic cases is unknown in 15(36.6%) cases, hepatitis in 10(24.3%) cases, pancreatitis in 6(14.6%) case,enterocolitis in 5(12.1%) cases, acute gastritis in 3(7.5%), acute pyelonephritis in 1(2.4%) case, and clonorchiasis in 1(2.4%) case. 3. Pathological diagnosis of 50 cases out of 86 cases of abnormal ultrasonography is GB stone in 36(72.0%) cases, pancreatic cancer in 5(10.0%) cases, hepatoma in 3(6.0%) cases, CBD stone in 4(8.0%) cases, pancreatic pseudocyst in 1(12.9%) case and liver abscess in 1(2.0%) case. 4. Diagnostic accuracy of ultrasonography of GB stone was 91.7%, false positive 2.8% and false negative 6.6%. 5. Ultrasonography has the advantage of noninvasiveness and easy performance, but the diagnostic accuracy of ultrasonography alone was low. Ultrasonography is considered as a good screening and complementary method for evaluation of right upper quadrant pain

  5. A Clinical Observation of Ultrasonographic Diagnosis on Right upper Quadrant Pain

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Suck Hong; Moon, T. Y.; Chang, H. Y.; Kim, B. S. [Pusan National University College of Medicine, Busan (Korea, Republic of)

    1982-12-15

    The author analyzed a total of 127 cases of ultrasonography studied for evaluation of the causes of right upper quadrant pain during ten months from Feb.1 to Nov. 30 1981, at the department of radiology, Busan national university and St. Benedict hospital. The results were as follows: 1. ultrasonographic findings of the total of 127 cases are normal in 41(32.3%) cases, and abnormal in 86(67.6%) cases. 2. Clinical diagnosis of normal ultrasonographic cases is unknown in 15(36.6%) cases, hepatitis in 10(24.3%) cases, pancreatitis in 6(14.6%) case,enterocolitis in 5(12.1%) cases, acute gastritis in 3(7.5%), acute pyelonephritis in 1(2.4%) case, and clonorchiasis in 1(2.4%) case. 3. Pathological diagnosis of 50 cases out of 86 cases of abnormal ultrasonography is GB stone in 36(72.0%) cases, pancreatic cancer in 5(10.0%) cases, hepatoma in 3(6.0%) cases, CBD stone in 4(8.0%) cases, pancreatic pseudocyst in 1(12.9%) case and liver abscess in 1(2.0%) case. 4. Diagnostic accuracy of ultrasonography of GB stone was 91.7%, false positive 2.8% and false negative 6.6%. 5. Ultrasonography has the advantage of noninvasiveness and easy performance, but the diagnostic accuracy of ultrasonography alone was low. Ultrasonography is considered as a good screening and complementary method for evaluation of right upper quadrant pain

  6. ARE LEFT HANDED SURGEONS LEFT OUT?

    OpenAIRE

    SriKamkshi Kothandaraman; Balasubramanian Thiagarajan

    2012-01-01

    Being a left-handed surgeon, more specifically a left-handed ENT surgeon, presents a unique pattern of difficulties.This article is an overview of left-handedness and a personal account of the specific difficulties a left-handed ENT surgeon faces.

  7. Muscle Articulations: Flexible Jaw Joints Made of Soft Tissues.

    Science.gov (United States)

    Uyeno, T A; Clark, A J

    2015-08-01

    This study surveys animals that use soft tissues rather than rigid links to build jaw joints. Hard biting elements are useful; they are used in piercing or shearing during feeding and interactive behaviors and can directly impact survival and reproduction. The best understood biting systems include biting elements that are mounted on rigid jaw links that form a joint capable of transmitting the bite reaction forces. As such, jaws must incorporate joints that resist compression. Many jaw joints are "sliding joints", in which jaw links come into direct contact and the shape of the sliding contact surfaces dictates possible motions. There are, however, organisms that have biting elements on jaws that are made of flexible muscle and connective tissues. If arranged as a muscular hydrostat, in which multiple orientations of the muscle fibers may co-contract to provide turgid skeletal support, the multifunctional joint not only (a) provides the force to move the biting elements, but also (b) creates repositionable pivots and (c) transmits bite reaction forces. Such flexible joints, termed "muscle articulations", may be important to a number of soft-bodied animals. In this survey, we review the function of previously described muscle articulations: the joints found between inarticulate brachiopods' valves, cephalopods' beaks, the hooks of kalyptorhynch flatworms, and errant polychaetes' jaws. We also review the morphology, physiology, and feeding behaviors of the hagfish as a putative muscle articulation in an effort to understand how this jawless craniate is capable of biting with surprising force, seemingly without the benefit of any obvious method of opposing the force of the dental plate that is used to remove portions of food. Initial analysis suggests that a muscle articulation may be a key feature in coordinating head and body movements to provide the leverage needed for strong "bites". © The Author 2015. Published by Oxford University Press on behalf of the

  8. Jaw Pain as a First Presentation in the Diagnosis of Breast Cancer.

    Science.gov (United States)

    Azadeh, Payam; Rakhashani, Nasser; Yaghobi Joybari, Ali; Gorji Bayani, Pegah; Sarbaz, Samaneh; Farasatinasab, Maryam

    2016-01-01

    The oral cavity is uncommon site for metastatic disease usually discovered secondary to malignancy. We encountered with a rare case in which metastasis to mandibular bone was the first clinical sign in the diagnosis of breast cancer without any radiographic findings. A 49-yr-old premenopausal woman, was referred to the Department of Medical Oncology of Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran in 2014, presented with pain and tenderness in the left mandibular and temporal bone and paresthesia of the lower left lip and chin. CT scan of mandible showed no significant finding. Four months later, she was referred with complaints left breast pain for 4 wk and worsening swelling, pain and paresthesia. Breast examination revealed a 2 cm firm nodule on the left breast. Based on her medical history and histopathological study, metastatic carcinoma of the breast was suspected. She has received chemoradiotherapy that led to complete relief of her symptoms and remission of the disease. In the presence of an ambiguous sign in oral cavity such as jaw pain or paresthesia, diagnostic examination of malignancy is recommended.

  9. SU-F-T-531: Determination of Site-Specific Dynamic-Jaw Versus Static-Jaw RapidArc Delivery

    International Nuclear Information System (INIS)

    Tien, C; Brewer, M; Studenski, M

    2016-01-01

    Purpose: Dynamic-jaw tracking maximizes the area blocked by both jaw and MLC in RapidArc. We developed a method to quantify jaw tracking. Methods: An Eclipse Scripting API (ESAPI) was used to export beam parameters for each arc’s control points. The specific beam parameters extracted were: gantry angle, control point number, meterset, x-jaw positions, y-jaw positions, MLC bank-number, MLC leaf-number, and MLC leaf-position. Each arc contained 178 control points with 120 MLC positions. MATLAB routines were written to process these parameters in order to calculate both the beam aperture (unblocked) size for each control point. An average aperture size was weighted by meterset. Jaw factor was defined as the ratio between dynamic-jaw to static-jaw aperture size. Jaw factor was determined for forty retrospectively replanned patients treated with static-jaw delivery sites including lung, brain, prostate, H&N, rectum, and bladder. Results: Most patients had multiple arcs and reduced-field boosts, resulting in 151 fields. Of these, the lowest (0.4722) and highest (0.9622) jaw factor was observed in prostate and rectal cases, respectively. The median jaw factor was 0.7917 meaning there is the potential unincreased blocking by 20%. Clinically, the dynamic-jaw tracking represents an area surrounding the target which would receive MLC-only leakage transmission of 1.68% versus 0.1% with jaws. Jaw-tracking was more pronounced at areas farther from the target. In prostate patients, the rectum and bladder had 5.5% and 6.3% lower mean dose, respectively; the structures closer to the prostate such as the rectum and bladder both had 1.4% lower mean dose. Conclusion: A custom ESAPI script was coupled with a MATLAB routine in order to extract beam parameters from static-jaw plans and their replanned dynamic-jaw deliveries. The effects were quantified using jaw factor which is the ratio between the meterset weighted aperture size for dynamic-jaw fields versus static-jaw fields.

  10. Predictable Technique to Register Retruded Contact Position (RCP) Using a Disposable Jaw Relation Recording Device.

    Science.gov (United States)

    Daher, Tony; Lobel, William A; Massad, Joseph; Ahuja, Swati; Danilov, Zarko Jack

    2015-05-01

    The dental literature presents various definitions and techniques to describe and register centric relation (CR) or centric occlusion (CO). Briefly reviewing the literature in relation to CR, this article proposes the use of the term retruded contact position (RCP), clinically defined as retruded, unstrained, repeatable position and where the mandibular movements start when a Gothic arch tracing is used. With this clinical definition, a technique can be easily selected that meets all the requirements of such position. The article discusses the use of a jaw recorder that is an intraorally graphic recording device that results in a tracing of mandibular movements in one plane, with the apex of the tracing indicating the retruded, unstrained, and repeatable relationship. The intersection of the arcs produced by the right and left working movement form the apex of the Gothic arch tracing. Several clinical situations using the jaw recorder are described. Clinicians can now quickly and accurately record RCP, balance complete, partial, or implant dentures, and orthopedically reposition the mandible. The technique achieves highly reliable and reproducible results.

  11. Florid cemento-osseous dysplasia: review of an uncommon fibro-osseous lesion of the jaw with important clinical implications.

    Science.gov (United States)

    Fenerty, Sarah; Shaw, Wei; Verma, Rahul; Syed, Ali B; Kuklani, Riya; Yang, Jie; Ali, Sayed

    2017-05-01

    Florid cemento-osseous dysplasia (FCOD) is a rare, benign, multifocal fibro-osseous dysplastic process affecting tooth-bearing areas of the jaw, characterized by replacement of normal trabecular bone with osseous tissue and dense acellular cementum in a fibrous stroma. It is one clinicopathologic variant in a spectrum of related non-neoplastic fibro-osseous lesions known as cemento-osseous dysplasias (CODs), thought to arise from elements of the periodontal ligament. Diagnosis primarily relies upon radiographic and clinical findings; unnecessary biopsy should be avoided, as inoculation with oral pathogens may precipitate chronic infection in these hypovascular lesions. Appropriate management of uncomplicated FCOD consists of periodic radiographic follow-up. Accordingly, it is important that both radiologists and clinicians performing endodontic interventions possess familiarity with this entity in order to prevent misdiagnosis and inappropriate intervention, which may result in a protracted clinical course. Lesions are usually asymptomatic in the absence of infection, typically discovered on routine dental radiographs or imaging performed for unrelated indications. Radiographically, the condition typically manifests as widespread non-expansile intraosseous masses of varying internal lucency and sclerosis that surround the root apices of vital teeth or edentulous areas in the posterior jaw. While all CODs share similar microscopic features, FCOD is distinguished by its multifocal distribution, involving two or more quadrants of the maxilla and mandible, often in a bilateral symmetric fashion. The vast majority of cases are sporadic, though few exhibit an autosomal dominant familial inheritance pattern. In this pictorial review, we discuss the radiologic characteristics of this entity, pertinent clinical and histologic features, differential diagnoses, and management options.

  12. Effects of Jaw Clenching and Jaw Alignment Mouthpiece Use on Force Production During Vertical Jump and Isometric Clean Pull.

    Science.gov (United States)

    Allen, Charles R; Fu, Yang-Chieh; Cazas-Moreno, Vanessa; Valliant, Melinda W; Gdovin, Jacob R; Williams, Charles C; Garner, John C

    2018-01-01

    Allen, CR, Fu, Y-C, Cazas-Moreno, V, Valliant, MW, Gdovin, JR, Williams, CC, and Garner, JC. Effects of jaw clenching and jaw alignment mouthpiece use on force production during vertical jump and isometric clean pull. J Strength Cond Res 32(1): 237-243, 2018-This study examined the effects of jaw clenching, a self-adapted, jaw-repositioning mouthpiece on force production during maximum countermovement vertical jump and maximum isometric midthigh clean pull assessments in an attempt to determine any ergogenic effect attributable to clenching, jaw-repositioning mouthpiece use, or the combination of both. Thirty-six male subjects performed vertical jump and isometric clean pull assessments from a force platform under various mouthpiece and clench conditions. A 3 × 2 (mouthpiece × clench) repeated-measures analysis of variance was conducted to analyze each of the following force production variables for both assessments: peak force, normalized peak force, and rate of force development. In addition, jump height was analyzed for the vertical jump. Results revealed improvements in peak force (F1,35 = 15.84, p ≤ 0.001, (Equation is included in full-text article.)= 0.31), normalized peak force (F1,35 = 16.28, p ≤ 0.001, (Equation is included in full-text article.)= 0.32), and rate of force development (F1,35 = 12.89, p = 0.001, (Equation is included in full-text article.)= 0.27) during the isometric clean pull assessment when participants maximally clenched their jaw, regardless of mouthpiece condition. There were no statistically significant differences in jump height, peak force, normalized peak force, or rate of force development during the vertical jump for any treatment condition. This study supports previous research demonstrating that the implementation of remote voluntary contractions such as jaw clenching can lead to concurrent activation potentiation and a resulting ergogenic effect during activities involving and requiring high-force production.

  13. The Effects of a Self-Adapted, Jaw Repositioning Mouthpiece and Jaw Clenching on Muscle Activity during Vertical Jump and Isometric Clean Pull Performance

    Directory of Open Access Journals (Sweden)

    Charles Allen

    2016-07-01

    Full Text Available Purpose: The purpose of this study was to investigate the effects of a self-adapted, jaw repositioning mouthpiece and jaw clenching on muscle activity during the countermovement vertical jump (CMVJ and isometric mid-thigh clean pull (MTCP. Methods:  Thirty-six healthy, recreationally trained males (n=36; age, 23 ± 2.8 years; height, 178.54 ± 9.0 cm; body mass, 83.09 ± 7.8 kg completed maximal CMVJ and MTCP assessments under six experimental conditions:  jaw repositioning mouthpiece plus clenching (MP+C, jaw repositioning mouthpiece with jaw relaxed (MP, traditional mouthguard plus clenching (MG+C, traditional mouthguard with jaw relaxed (MG, no mouthpiece plus clenching (NoMP+C and no mouthpiece with jaw relaxed (NoMP while muscle activity of the dominant leg medial gastrocnemius (G, medial hamstring (H, vastus medialis (VMO, and erector spinae (ES was recorded. Results:  Repeated measures ANOVA revealed no changes in MTCP muscle activation for any mouthpiece or clench condition. Jaw clenching, regardless of mouthpiece condition, significantly improved prime mover muscle activation during CMVJ (p .05. Conclusion:  These findings support jaw clenching as a viable technique to elicit concurrent activation potentiation (CAP of prime mover muscle activity during dynamic but not isometric physical activity. Keywords: jaw repositioning mouthpiece, jaw clenching, concurrent activation potentiation, muscle activation

  14. Left-sided appendicitis: review of 95 published cases and a case report.

    Science.gov (United States)

    Akbulut, Sami; Ulku, Abdullah; Senol, Ayhan; Tas, Mahmut; Yagmur, Yusuf

    2010-11-28

    To give an overview of the literature on left-sided acute appendicitis (LSAA) associated with situs inversus totalis (SIT) and midgut malrotation (MM). We present a new case of LSAA with SIT and a literature review of studies published in the English language on LSAA, accessed via PubMed and Google Scholar databases. Ninety-five published cases of LSAA were evaluated and a 25-year-old female, who presented to our clinic with left lower abdominal pain caused by LSAA, is reported. In the reviewed literature, fifty-seven patients were male and 38 were female with an age range of 8 to 82 years and a median age of 29.1 ± 15.9 years. Sixty-six patients had SIT, 23 had MM, three had cecal malrotation, and two had a previously unnoted congenital abnormality. Fifty-nine patients had presented to the hospital with left lower, 14 with right lower and seven with bilateral lower quadrant pain, and seven subjects complained of left upper quadrant pain. The diagnosis was established preoperatively in 49 patients, intraoperatively in 19, and during the postoperative period in five; 14 patients were aware of having this anomaly. The data of eight patients were not unavailable. Eleven patients underwent laparoscopic appendectomy, which was combined with cholecystectomy in two cases. Histopathological examination of the appendix specimens revealed adenocarcinoma in only two of 95 patients. The diagnosis of left lower quadrant pain is based on well-established clinical symptoms, physical examination and physician's experience.

  15. Solitary central osteoma of the jaws: a diagnostic dilemma.

    Science.gov (United States)

    Kaplan, Ilana; Nicolaou, Zoe; Hatuel, Dorian; Calderon, Shlomo

    2008-09-01

    Osteomas are relatively rare benign osteogenic neoplasms, characterized by the proliferation of compact and/or cancellous bone. Osteomas can develop as peripheral (periosteal) masses attached to the cortical plates or as central lesions arising from endosteal bone surfaces. Although multiple osteomas of the jaws are a hallmark of Gardner syndrome (familial adenomatous polyposis), nonsyndromic cases are typically solitary. A search of the literature identified 91 well documented cases of solitary osteoma of the jaws published since 1955: 93.4% were peripheral and only 6.6% central, a ratio of 14:1 in favor of peripheral osteomas. Solitary central osteomas of the jaws seem to be very rare, with only 6 such cases reported since 1955. Adding the 4 new cases described here brings the total to 10 central osteomas, 30% occurring in the maxilla and 70% in the mandible. Whereas peripheral osteomas are fairly easy to diagnose, central osteomas pose a more challenging diagnostic problem and need to be differentiated from other similar lesions of the jaws, such as central ossifying fibroma, condensing osteitis, idiopathic osteosclerosis, osteoblastoma, cementoblastoma, and complex odontoma. With such a low number of cases of central osteoma reported, the objectives of the present report are to describe 4 new cases, analyze the clinical and radiographic characteristics, and discuss the features which distinguish these lesions from other similar lesions of the jaws.

  16. Fibro-osseous lesions of the jaws in Ibadan, Nigeria.

    Science.gov (United States)

    Lasisi, Taye Jemilat; Adisa, Akinyele Olumuyiwa; Olusanya, Adeola Adenike

    2014-03-01

    Fibro-osseous lesion is a broad term for a diverse group of jaw disorders characterized by the replacement of normal bone by a benign fibrous connective tissue matrix. The present study reviewed the clinico-pathologic characteristics of all biopsied cases of fibro-osseous lesions at our hospital from 1990 to 2011, which we hope will serve as a reference database regionally. A retrospective clinicopathological review of all histologically diagnosed cases of jaw fibro-osseous lesions seen at our Hospital between January 1990 and December 2011. A total of one hundred and twenty one fibro-osseous lesions of jaws were histological diagnosed in the 22-year period. The lesions documented included ossifying fibroma (62%), fibrous dysplasia (37.2%) and florid cemento-osseous dysplasia (0.8%). Fibro-osseous lesions of jaws were more in females (61.2%) than males (38.8%), giving a male to female ratio of 1:1.6. Fibro-osseous lesions of jaw are a diverse group and since it may not be possible to adequately separate them histologically, the development of a more rigorous clinical algorithm as indicated in this study is essential in reaching a final diagnosis especially in resource-limited settings.

  17. Thirteen cases of jaw osteonecrosis in patients on bisphosphonate therapy.

    Science.gov (United States)

    Vieillard, Marie-Hélène; Maes, Jean-Michel; Penel, Guillaume; Facon, Thierry; Magro, Leonardo; Bonneterre, Jacques; Cortet, Bernard

    2008-01-01

    We report on our experience with 13 cases of jaw osteonecrosis in patients treated with amino-bisphosphonates. Data were collected by a regional observatory for jaw osteonecrosis in northern France via letters sent to all physicians likely to manage patients with this condition. All study patients were evaluated at a multidisciplinary jaw osteonecrosis clinic between June and December 2005. We identified 13 cases, in 12 women and 1 man, with a mean age of 62.6 years. Intravenous amino-bisphosphonate therapy was given for metastatic bone disease from breast cancer in 7 patients and multiple myeloma in 5 patients; the remaining patient was on oral alendronate for osteoporosis. Mean treatment duration was 24 months. A history of dental extraction was found in 11 (84.6%) patients. The mandible was involved in all 13 patients and the maxillary in 3 (23%) patients. Amino-bisphosphonate therapy was discontinued in all 13 patients. We suggest a classification scheme for the clinical and computed-tomography patterns seen in our patients. Jaw osteonecrosis is a severe complication of amino-bisphosphonate therapy. In addition to the application of published guidelines, we propose discontinuing bisphosphonate therapy whenever possible. We are evaluating our classification scheme to identify early diagnostic criteria and/or clinical and computed-tomography outcome criteria that would improve the management of patients with jaw osteonecrosis.

  18. Bisphosphonate-related osteonecrosis of the jaw around dental implants in the maxilla: report of a case.

    Science.gov (United States)

    Shirota, Tatsuo; Nakamura, Atsushi; Matsui, Yoshiro; Hatori, Masahi; Nakamura, Masanori; Shintani, Satoru

    2009-12-01

    We describe a patient who developed bisphosphonate (BP)-related osteonecrosis of the jaw (ONJ) around implants in the upper molar area. The patient was a 54-year-old woman with ulceration of the gum, bone exposure, and severe spontaneous pain around implants in the upper left molar area. She had received BPs intravenously for 2 years to treat bone metastases of breast cancer. She was diagnosed with BP-related ONJ. Sequestrum including implants was resected, and hyperbaric oxygen therapy was performed. Undecalcified ground sections were prepared from the resected bone around the implants and stained with toluidine blue. For the bone around the lesion, decalcified sections were prepared, and examined by histological and immunohistological analysis. The surgical wound became completely covered with mucosal epithelia, and postoperative pain disappeared. No recurrence of ONJ was noted during a 6-month postoperative follow-up period. However, the patient died from metastatic disease. Although histopathological examination of the resected jaw bone revealed sequestrum, osseointegration of the implant was maintained. In the area around the lesion, there was no progression of bone necrosis, and reactive bone formation, fibrosis, and invasion of lymphoid cells into the marrow cavity were observed. There is no effective treatment for ONJ caused by BPs, and conservative therapy based on clinicians' experience is recommended. However, if chemotherapy is planned, or if bone necrosis around implants is thought to harbor infection, the option of jaw resection should be considered.

  19. Geometric quasi-similarity: Case of nozzles with quadrant-shaped inlet

    Czech Academy of Sciences Publication Activity Database

    Tesař, Václav

    2016-01-01

    Roč. 248, September (2016), s. 246-256 ISSN 0924-4247 R&D Projects: GA ČR GA13-23046S Institutional support: RVO:61388998 Keywords : nozzles * local geometric similarity * quasi-similarity * reynolds number * euler number * quadrant nozzles Subject RIV: BK - Fluid Dynamics Impact factor: 2.499, year: 2016 http://ac.els-cdn.com/S0924424716303399/1-s2.0-S0924424716303399-main.pdf?_tid=79a1397c-6e8d-11e6-893f-00000aacb361&acdnat=1472546639_01cebf4490123f8e5db56d9c4cda5fd5

  20. Four quadrant control circuit for a brushless three-phase dc motor

    Science.gov (United States)

    Nola, Frank J. (Inventor)

    1987-01-01

    A control circuit is provided for a brushless three-phase dc motor which affords four quadrant control from a single command. The control circuit probes acceleration of the motor in both clockwise and counterclockwise directions and braking and generation in both clockwise and counterclockwise directions. In addition to turning on individual transistors of the transistor pairs connected to the phase windings of the motor for 120 deg periods while the other transistor of that pair is off, the control circuit also provides, in a future mode of operation, turning the two transistors of each pair on and off alternately at a phase modulation frequency during such a 120 deg period. A feedback signal is derived which is proportional to the motor current and which has a polarity consistent with the command signal, such that negative feedback results.

  1. Supporting document for the Southeast Quadrant historical tank content estimate report for SY-tank farm

    International Nuclear Information System (INIS)

    Brevick, C.H.; Gaddis, L.A.; Consort, S.D.

    1995-01-01

    Historical Tank Content Estimate of the Southeast Quadrant provides historical evaluations on a tank by tank basis of the radioactive mixed wastes stored in the underground double-shell tanks of the Hanford 200 East and West Areas. This report summarizes historical information such as waste history, temperature profiles, psychrometric data, tank integrity, inventory estimates and tank level history on a tank by tank basis. Tank Farm aerial photos and in-tank photos of each tank are provided. A brief description of instrumentation methods used for waste tank surveillance are included. Components of the data management effort, such as Waste Status and Transaction Record Summary, Tank Layer Model, Supernatant Mixing Model, Defined Waste Types, and Inventory Estimates which generate these tank content estimates, are also given in this report

  2. Ewing’s Sarcoma of Ilium, Presenting as Right Lower Quadrant Pain

    Directory of Open Access Journals (Sweden)

    Osama Saleh Alshaya

    2015-01-01

    Full Text Available Ewing’s sarcoma is a highly malignant tumor of bone and is more common in children in the age group of 10 to 20 years. Sometimes the classic clinical and radiological presentation of Ewing’s sarcoma may not be the norm and patient may have an atypical presentation leading to diagnostic confusion. This situation is especially true for Ewing’s sarcoma involving iliac bone. We report a case of Ewing’s sarcoma involving the right ilium in a patient presenting with right lower quadrant pain and nonspecific radiological changes. To the best of our knowledge, this scenario has not been reported in literature. We recommend early magnetic resonance imaging and computed tomography to diagnose the disease early when there is slightest suspicion of the disease.

  3. Imaging the child with right lower quadrant pain and suspected appendicitis: current concepts

    Energy Technology Data Exchange (ETDEWEB)

    Sivit, Carlos J. [Departments of Radiology and Pediatrics, Rainbow Babies and Childrens Hospital of the University Hospitals of Cleveland and Case Western Reserve School of Medicine, Euclid Avenue, 11100, 44106-5056, Cleveland, OH (United States)

    2004-06-01

    Acute appendicitis is the most common condition presenting with right lower quadrant pain requiring acute surgical intervention in childhood. The clinical diagnosis of acute appendicitis is often not straightforward and can be challenging. Approximately one-third of children with the condition have atypical clinical findings and are initially managed non-operatively. Complications usually result from perforation and include abscess formation, peritonitis, sepsis, bowel obstruction and death. Cross-sectional imaging with sonography and computed tomography (CT) have proven useful for the evaluation of suspected acute appendicitis in children. The principal advantages of sonography are its lower cost, lack of ionizing radiation, and ability to precisely delineate gynecologic disease. The principal advantages of CT are its operator independency with resultant higher diagnostic accuracy, enhanced delineation of disease extent in perforated appendicitis, and improved patient outcomes including decreased negative laparotomy and perforation rates. (orig.)

  4. Lateral geniculate lamination and the corticogeniculate projection: a potential role in binocular vision in the quadrants.

    Science.gov (United States)

    McIlwain, J T

    1995-02-21

    Students of vision have long speculated about the functions of the distinct lamination of the lateral geniculate nucleus and the massive return projection from visual cortex to this thalamic structure. This paper proposes that these features of the visual system reflect, in part at least, its solution to a geometric problem inherent in binocular vision. Points in the visual quadrants are imaged on geometrically non-corresponding retinal points. Two such retinal loci, optically conjugate with a given visual point at one fixation distance or angle, will correspond to no single visual point at other fixation distances or angles. This raises potential problems for visual cortical neurons sensitive to a narrow range of binocular disparities. If these neurons are to function optimally at a variety of fixation distances and angles, their disparity tuning must be variable. It is suggested here that such dynamic disparity tuning is effected by the corticogeniculate projection acting on the segregated ocular representations in the geniculate laminae.

  5. Four Quadrants Integrated Transformers for Dual-input Isolated DC-DC Converters

    DEFF Research Database (Denmark)

    Ouyang, Ziwei; Zhang, Zhe; Andersen, Michael A. E.

    2012-01-01

    ) space orthogonal flux is proposed in this letter. And thus a new geometry core and relative winding arrangements are proposed in accordance with the orthogonal flux decoupling technology. Due to the four secondary windings are arranged in a quadratic pattern at the base core plate with the two...... perpendicular primary windings, a name of “four quadrants integrated transformers” (FQIT) is therefore given to the proposed construction. Since the two primary windings are uncoupled, the FQIT allows the two input power stages to transfer the energy into the output load simultaneously or at any...... timemultiplexing scheme, which can optimize the utilization of input sources, simplify the system structure and reduce the overall cost, so they are attractive for the hybrid renewable power system. Section IV initiates a discussion for the advantages of the FQIT. In order to verify the feasibility of the FQIT...

  6. Repeated tongue lift movement induces neuroplasticity in corticomotor control of tongue and jaw muscles in humans

    DEFF Research Database (Denmark)

    Komoda, Yoshihiro; Lida, Takashi; Kothari, Mohit

    2015-01-01

    This study investigated the effect of repeated tongue lift training (TLT) on the excitability of the corticomotor representation of the human tongue and jaw musculature. Sixteen participants performed three series of TLT for 41min on each of 5 consecutive days. Each TLT series consisted of two...... pressure levels (5kPa and 10kPa). All participants underwent transcranial magnetic stimulation (TMS) and electromyographic (EMG) recordings of motor evoked potentials (MEPs) in four sessions: (1) before TLT on Day 1 (baseline), (2) after TLT on Day 1, (3) before TLT on Day 5, and (4) after TLT on Day 5....... EMG recordings from the left and right tongue dorsum and masseter muscles were made at three pressure levels (5kPa, 10kPa, 100% tongue lift), and tongue, masseter, and first dorsal interosseous (FDI) MEPs were measured. There were no significant day-to-day differences in the tongue pressure during...

  7. Simulations and Analysis and Operating Regime as Rectifier with Power Factor Correction of Two - Quadrant Converter with RNSIC

    Directory of Open Access Journals (Sweden)

    PLETEA, I.V.

    2009-10-01

    Full Text Available In this paper, a new topology for a two-quadrant converter is presented. In the AC/DC transfer mode, the converter works as a rectifier with near sinusoidal input currents (RNSIC, while in the DC/AC transfer mode it works as a square-wave pulse switching inverter. We offer some suggestions for the converter design and realize a comparison with a two-quadrant PWM converter. The new converter is characterized by smaller power losses, reduced EMI problems and higher reliability.

  8. Bisphosphonate related osteonecrosis of the jaws: report of two cases

    Energy Technology Data Exchange (ETDEWEB)

    Han, Jin Woo [College of Dentistry, Gangneung Wonju National University, Gangneung (Korea, Republic of)

    2011-09-15

    Bisphosphonates are compounds used to treat osteoporosis and malignant bone metastasis. Despite the benefits related to the use of these medications, osteonecrosis of the jaws is a significant complication in a subset of patients receiving these drugs. This complication occurs either spontaneously or after a simple dento-alveolar surgery. Recently there were two patients who showed the features of bisphosphonate related osteonecrosis of the jaws (BRONJ) in Gangneung Wonju National University Dental Hospital. The patients revealed the clinical and radiological features of classical osteomyelitis. This report presents two cases of BRONJ which were examined by plain radiography and computed tomography.

  9. The relationships among jaw-muscle fiber architecture, jaw morphology, and feeding behavior in extant apes and modern humans.

    Science.gov (United States)

    Taylor, Andrea B; Vinyard, Christopher J

    2013-05-01

    The jaw-closing muscles are responsible for generating many of the forces and movements associated with feeding. Muscle physiologic cross-sectional area (PCSA) and fiber length are two architectural parameters that heavily influence muscle function. While there have been numerous comparative studies of hominoid and hominin craniodental and mandibular morphology, little is known about hominoid jaw-muscle fiber architecture. We present novel data on masseter and temporalis internal muscle architecture for small- and large-bodied hominoids. Hominoid scaling patterns are evaluated and compared with representative New- (Cebus) and Old-World (Macaca) monkeys. Variation in hominoid jaw-muscle fiber architecture is related to both absolute size and allometry. PCSAs scale close to isometry relative to jaw length in anthropoids, but likely with positive allometry in hominoids. Thus, large-bodied apes may be capable of generating both absolutely and relatively greater muscle forces compared with smaller-bodied apes and monkeys. Compared with extant apes, modern humans exhibit a reduction in masseter PCSA relative to condyle-M1 length but retain relatively long fibers, suggesting humans may have sacrificed relative masseter muscle force during chewing without appreciably altering muscle excursion/contraction velocity. Lastly, craniometric estimates of PCSAs underestimate hominoid masseter and temporalis PCSAs by more than 50% in gorillas, and overestimate masseter PCSA by as much as 30% in humans. These findings underscore the difficulty of accurately estimating jaw-muscle fiber architecture from craniometric measures and suggest models of fossil hominin and hominoid bite forces will be improved by incorporating architectural data in estimating jaw-muscle forces. Copyright © 2013 Wiley Periodicals, Inc.

  10. Jaw morphology and ontogeny in five species of Ophryothrocha

    DEFF Research Database (Denmark)

    Macnaughton, Martin Oliver; Worsaae, Katrine; Eibye-Jacobsen, Danny

    2010-01-01

    Detailed scanning electron microscopy of jaws within the genus Ophryotrocha (Dorvilleidae, Annelida) was performed on 871 jaw parts. The investigations resulted in new understandings of the ontogeny and jaw morphology and have systematic implications for the family. Five species in the genus (Oph...

  11. Supporting document for the north east quadrant historical tank content estimate report for C-Tank Farm

    International Nuclear Information System (INIS)

    Brevick, C.H.; Gaddis, L.A.; Walsh, A.C.

    1994-06-01

    This Supporting Document provides historical in-depth characterization information gathered on C-Tank Farm, such as historical waste transfer and level data, tank physical information, temperature data, sampling data, and drywell and liquid observation well data for Historical Tank Content Estimate Report of the NE Quadrant and the Hanford 200 East Areas

  12. A systematic review of posture and psychosocial factors as contributors to upper quadrant musculoskeletal pain in children and adolescents.

    Science.gov (United States)

    Prins, Yolandi; Crous, Lynette; Louw, Q A

    2008-01-01

    Musculoskeletal pain has become a major symptomatic complaint among children and adolescents and is increasingly occurring at a younger age. This systematic review was done to evaluate the evidence for the contribution of posture and psychosocial factors to the development of upper quadrant musculoskeletal pain in children and adolescents. The review describes the measurement tools used to assess musculoskeletal pain, sitting posture, and psychosocial factors. Two independent reviewers searched seven databases for observational studies that included prospective and cross-sectional study designs. Ten studies were extracted and assessed by two reviewers using the Critical Appraisal Form-Quantitative Studies (Law et al, 1998). The studies measured upper quadrant musculoskeletal pain as an outcome measure. Five studies evaluated sitting posture and found an association between the duration of static sitting and upper quadrant musculoskeletal pain. Six studies measured psychosocial factors of which depression, stress, and psychosomatic symptoms were the factors most commonly found to influence the development of upper quadrant musculoskeletal pain. The eligible studies used different pain measurement tools and different measurement tools to assess sitting posture and psychosocial factors. This review concludes that the duration of sitting posture and psychosocial factors may influence the experience of musculoskeletal pain among children and adolescents.

  13. 18 CFR 38.2 - Incorporation by reference of North American Energy Standards Board Wholesale Electric Quadrant...

    Science.gov (United States)

    2010-04-01

    ... REGULATIONS UNDER THE FEDERAL POWER ACT BUSINESS PRACTICE STANDARDS AND COMMUNICATION PROTOCOLS FOR PUBLIC... Quadrant standards. (a) All entities to which § 38.1 is applicable must comply with the following business practice and electronic communication standards promulgated by the North American Energy Standards Board...

  14. Supporting document for the north east quadrant historical tank content estimate report for AX-tank farm

    International Nuclear Information System (INIS)

    Brevick, C.H.; Gaddis, L.A.; Walsh, A.C.

    1994-06-01

    This Supporting Document provides historical in-depth characterization information gathered in AX-Tank Farm, such as historical waste transfer and level data, tank physical information, temperature data, sampling data, and drywell and liquid observation well data for Historical Tank Content Estimate Report of the NE Quadrant and the Hanford 200 East Areas

  15. Radiographic positions of femoral ACL, AM and PL centres : accuracy of guidelines based on the lateral quadrant method

    NARCIS (Netherlands)

    Luites, Joan W.H.; Verdonschot, Nico

    2017-01-01

    Purpose: Femoral tunnel positioning is an important factor in anatomical ACL reconstructions. To improve accuracy, lateral radiographic support can be used to determine the correct tunnel location, applying the quadrant method. Piefer et al. (Arthroscopy 28:872–881, 2012) combined various outcomes

  16. The ideal male jaw angle--An Internet survey.

    Science.gov (United States)

    Mommaerts, Maurice Y

    2016-04-01

    The ideal male jaw angle has not been established. With the advent of additive manufacturing, precise customized shaping is a reality. This study aimed to define the ideal masculine mandibular angle as an aid for 3-dimensional (3D) design. An Internet survey was conducted using black/white photographs of celebrities and non-celebrities. Preferences regarding gonial angle (profile and frontal views), intergonial width and vertical jaw angle position (face frontal view), and angle curvature and definition in oblique views were obtained using simplified, unbalanced Likert scales. Constructs were defined for planning 3D implant designs. The preferred jaw angle had these characteristics: 130° in face profile view, intergonial width similar to facial width, vertical position in frontal view at the oral commissure or at least not below the lower lip, jawline slope in the face frontal view nearly parallel to (with a maximum 15° downward deviation from) a line extending from the lateral canthus to the alare, ascending ramus slope 65°-75° to the Frankfort horizontal, and curvature in the oblique view visible from earlobe to chin and not pointy. Photogrammetric analysis of panel preferences lead to constructs with values useful for the design of 3D printed jaw angles. Copyright © 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  17. Ameloblastomatous Change in Radicular Cyst of The Jaw in a ...

    African Journals Online (AJOL)

    2015-06-01

    Jun 1, 2015 ... SUMMARY. Objective: To determine the incidence, age, gender, jaw-sites and subtypes of radicular cyst, and to determine the incidence of ameloblastomatous change in radicular cyst in a Nigerian population. Method: A 10-year retrospective analysis of all diagnosed orofacial lesions in the Department of ...

  18. Non-oncologic imaging of the oral cavity and jaws.

    Science.gov (United States)

    Mosier, Kristine M

    2008-02-01

    The unique and specialized structures of the oral cavity and jaws give rise to a myriad of diverse developmental, inflammatory, and benign lesions or conditions. This article reviews the imaging of common lesions and their variants, and reviews several rare but important lesions. Guidelines and algorithms for approaching the differential diagnosis are provided.

  19. [A boy with a swelling under his right jaw].

    Science.gov (United States)

    Gremmer, Jessica E; Moes, A R Roelof

    2015-01-01

    A 12-year-old boy presented with a painful swelling under his right jaw. Cat scratch disease was confirmed serologically. Two months later the swelling had increased in size and had become red. There was obvious fluctuation, which indicated abscess formation. After incision and drainage of the abscess, the swelling resolved within two weeks.

  20. The adaptative response of jaw muscles to varying functional demands

    NARCIS (Netherlands)

    Grünheid, T.; Langenbach, G.E.J.; Korfage, J.A.M.; Zentner, A.; van Eijden, T.M.G.J.

    2009-01-01

    Jaw muscles are versatile entities that are able to adapt their anatomical characteristics, such as size, cross-sectional area, and fibre properties, to altered functional demands. The dynamic nature of muscle fibres allows them to change their phenotype to optimize the required contractile function

  1. A Classification System for Recurrent Ameloblastoma of the Jaws ...

    African Journals Online (AJOL)

    A Classification System for Recurrent Ameloblastoma of the Jaws- Review of 30 Cases in Nigerians. GT Arotiba, AO Effiom, ASO Ayodele, MO Ogundana, MO Gbotolorun, HO Olasoji, O James, AL Ladeinde, VI Ugboko, KC Ndukwe, IC Ikem, RO Braimah ...

  2. Conservative Surgical Treatment of the Jaw Cysts in Children: Case ...

    African Journals Online (AJOL)

    Materials and Methods: This article presents case series of marsupialization in jaw cysts associated with impacted teeth in five children. A total of nine impacted teeth within the cystic lesions were observed. Results: Complete resolution of all cystic lesions and simultaneous eruption of six impacted teeth within the cyst were ...

  3. Assessment of the survival of dental implants in irradiated jaws ...

    African Journals Online (AJOL)

    Background: In patients undergoing head and neck surgery for various pathologic conditions, implants are one of the best restorative options and are increasing widely used. Therefore, we evaluated the success of dental implants in the irradiated jaws of patients following treatment of oral cancer oral cancer treated patients ...

  4. routine radiographic findings in clinically healthy edentulous jaw ...

    African Journals Online (AJOL)

    2012-08-08

    Aug 8, 2012 ... Objective: To describe the role of routine radiographic examination of clinically healthy completely edentulous jaws prior to fabrication of the first set of complete dentures. Design: Cross-sectional retrospective descriptive study. Settings: The departments of Conservative and Prosthetic Dentistry, and Oral ...

  5. A novel four quadrant laser sphincterotomy for idiopathic severe anal stenosis

    Directory of Open Access Journals (Sweden)

    Ashwin Porwal

    2018-01-01

    Full Text Available Anal stricture or stenosis, though uncommon, is disabling condition. It affects the quality of life due to pain, bleeding and difficulty in defecation, incontinence or increased frequency. It occurs when the normally pliable anoderm is replaced with fibrotic connective tissue, leading to an abnormally tight and inelastic anal canal. Mostly it occurs secondary to trauma, iatrogeny, inflammatory diseases, radiation or neoplasia. The treatment of anal stricture is generally considered to be difficult and various methods of treatment have been suggested. It is often unresponsive to conservative medical management. The surgical procedures such as dilatations and anoplasty are associated with significant complications which make it a difficult treatment challenge. Several good treatment options are available currently. Through this case, we report and explore a new medical treatment for anal strictures with four quadrant laser sphincterotomy. Resumo: A estritura ou estenose anal, embora incomum, é problema incapacitante. Essa condição afeta a qualidade de vida por causa da dor, do sangramento e da dificuldade de defecação, de incontinência ou aumento da frequência. A estenose anal ocorre quando o anoderma, normalmente flexível, foi substituído por tecido conjuntivo fibrótico, e o resultado é um canal anal anormalmente estenosado e inelástico. Na maioria dos casos, a estenose anal ocorre secundariamente a trauma, por causa iatrogênica, por doença inflamatória, radiação ou neoplasia. Em geral, se considera que o tratamento dessa condição é tarefa difícil, tendo sido sugeridos diversos métodos de tratamento. Com frequência a estenose anal não responde ao tratamento clínico conservador. Procedimentos cirúrgicos como as dilatações ou a anoplastia estão associados a complicações significativas, implicando difícil desafio terapêutico. Atualmente, o cirurgião conta com várias opções terapêuticas satisfatórias. No

  6. Building Finite Element Models to Investigate Zebrafish Jaw Biomechanics.

    Science.gov (United States)

    Brunt, Lucy H; Roddy, Karen A; Rayfield, Emily J; Hammond, Chrissy L

    2016-12-03

    Skeletal morphogenesis occurs through tightly regulated cell behaviors during development; many cell types alter their behavior in response to mechanical strain. Skeletal joints are subjected to dynamic mechanical loading. Finite element analysis (FEA) is a computational method, frequently used in engineering that can predict how a material or structure will respond to mechanical input. By dividing a whole system (in this case the zebrafish jaw skeleton) into a mesh of smaller 'finite elements', FEA can be used to calculate the mechanical response of the structure to external loads. The results can be visualized in many ways including as a 'heat map' showing the position of maximum and minimum principal strains (a positive principal strain indicates tension while a negative indicates compression. The maximum and minimum refer the largest and smallest strain). These can be used to identify which regions of the jaw and therefore which cells are likely to be under particularly high tensional or compressional loads during jaw movement and can therefore be used to identify relationships between mechanical strain and cell behavior. This protocol describes the steps to generate Finite Element models from confocal image data on the musculoskeletal system, using the zebrafish lower jaw as a practical example. The protocol leads the reader through a series of steps: 1) staining of the musculoskeletal components, 2) imaging the musculoskeletal components, 3) building a 3 dimensional (3D) surface, 4) generating a mesh of Finite Elements, 5) solving the FEA and finally 6) validating the results by comparison to real displacements seen in movements of the fish jaw.

  7. Jaw-muscle fiber architecture in tufted capuchins favors generating relatively large muscle forces without compromising jaw gape

    Science.gov (United States)

    Taylor, Andrea B.; Vinyard, Christopher J.

    2009-01-01

    Cebus apella is renowned for its dietary flexibility and capacity to exploit hard and tough objects. Cebus apella differs from other capuchins in displaying a suite of craniodental features that have been functionally and adaptively linked to their feeding behavior, particularly the generation and dissipation of relatively large jaw forces. We compared fiber architecture of the masseter and temporalis muscles between the tufted capuchin (C. apella; n = 12 ) and two “untufted” capuchins (C. capuchinus, n = 3; C. albifrons, n = 5). These three species share broadly similar diets, but tufted capuchins occasionally exploit mechanically challenging tissues. We tested the hypothesis that C. apella exhibits architectural properties of their jaw muscles that facilitate relatively large forces, including relatively greater physiologic cross-sectional areas (PCSA), more pinnate fibers, and lower ratios of mass to tetanic tension (Mass/P0). Results show some evidence supporting these predictions, as C. apella has relatively greater superficial masseter, whole masseter, and temporalis PCSAs, significantly so only for the temporalis following Bonferroni adjustment. Capuchins did not differ in pinnation angle or Mass/P0. As an architectural trade-off between maximizing muscle force and muscle excursion/contraction velocity, we also tested the hypothesis that C. apella exhibits relatively shorter muscle fibers. Contrary to our prediction, there are no significant differences in relative fiber lengths between tufted and untufted capuchins. Therefore, we attribute the relatively greater PCSAs in C. apella primarily to their larger muscle masses. These findings suggest that relatively large jaw-muscle PCSAs can be added to the suite of masticatory features that have been functionally linked to the exploitation of a more resistant diet by C. apella. By enlarging jaw-muscle mass to increase PCSA, rather than reducing fiber lengths and increasing pinnation, tufted capuchins appear

  8. High-precision positioning system of four-quadrant detector based on the database query

    Science.gov (United States)

    Zhang, Xin; Deng, Xiao-guo; Su, Xiu-qin; Zheng, Xiao-qiang

    2015-02-01

    The fine pointing mechanism of the Acquisition, Pointing and Tracking (APT) system in free space laser communication usually use four-quadrant detector (QD) to point and track the laser beam accurately. The positioning precision of QD is one of the key factors of the pointing accuracy to APT system. A positioning system is designed based on FPGA and DSP in this paper, which can realize the sampling of AD, the positioning algorithm and the control of the fast swing mirror. We analyze the positioning error of facular center calculated by universal algorithm when the facular energy obeys Gauss distribution from the working principle of QD. A database is built by calculation and simulation with MatLab software, in which the facular center calculated by universal algorithm is corresponded with the facular center of Gaussian beam, and the database is stored in two pieces of E2PROM as the external memory of DSP. The facular center of Gaussian beam is inquiry in the database on the basis of the facular center calculated by universal algorithm in DSP. The experiment results show that the positioning accuracy of the high-precision positioning system is much better than the positioning accuracy calculated by universal algorithm.

  9. Quadrant Dynamic with Automatic Plateau Limit Histogram Equalization for Image Enhancement

    Directory of Open Access Journals (Sweden)

    P. Jagatheeswari

    2014-01-01

    Full Text Available The fundamental and important preprocessing stage in image processing is the image contrast enhancement technique. Histogram equalization is an effective contrast enhancement technique. In this paper, a histogram equalization based technique called quadrant dynamic with automatic plateau limit histogram equalization (QDAPLHE is introduced. In this method, a hybrid of dynamic and clipped histogram equalization methods are used to increase the brightness preservation and to reduce the overenhancement. Initially, the proposed QDAPLHE algorithm passes the input image through a median filter to remove the noises present in the image. Then the histogram of the filtered image is divided into four subhistograms while maintaining second separated point as the mean brightness. Then the clipping process is implemented by calculating automatically the plateau limit as the clipped level. The clipped portion of the histogram is modified to reduce the loss of image intensity value. Finally the clipped portion is redistributed uniformly to the entire dynamic range and the conventional histogram equalization is executed in each subhistogram independently. Based on the qualitative and the quantitative analysis, the QDAPLHE method outperforms some existing methods in literature.

  10. METAL DELM - metal avrelianis contribution to the study of mining coins and anonymous quadrantes

    Directory of Open Access Journals (Sweden)

    Vojvoda Mirjana D.

    2016-01-01

    Full Text Available In the course of rescue archaeological investigations at the Viminacium necropolis of Vi{e Grobalja in 1984, one anonymous quadrans of the VIII Apollo group was discovered (cat. 1. It was discovered in trench 63 in the immediate vicinity of a grave with an inhumation (G 343 that, besides two pottery vessels, also yielded as grave offerings one as of Faustina the Elder, minted after her death, in AD 141. Other finds presented here are four specimens of Roman mining coins from the private collection of Petar Fajfri} from [abac (cat. 2-5. All specimens come from the well known site of Duge Njive in the area of the village of Banatsko Polje (Bogati} borough where, by all appearances, are the remains of a vicus or smaller settlement. Five specimens of mining coins from that site have already been published. Both mining coins and anonymous quadrantes represent, in general, rare types of numismatic finds. Nine anonymous quadrantes are known so far from the territory of Serbia (Table 1 and the provenance is known for three specimens from the region of Guberevac-Babe (Kosmaj, housed in the National Museum in Belgrade. All three belong to the Minerva group with an owl facing to the right represented on the reverse. For two more anonymous quadrantes the place of discovery is known: one specimen comes from Singidunum and belongs to the Mercury group and the other that was found at Viminacium and is the subject of this paper is of the Apollo group. There are four more specimens from unknown sites for which it is assumed that they come from the Upper Moesia territory. Two of them are from the Vajfert collection and two from the Kovačević collection in the National Museum in Belgrade, There has, however, been a somewhat greater number (38 of Roman mining coins discovered in Serbia (Table 1. We know the finding locations of 25 of them: from the Kosmaj area (Babe, Guberevac and Stojnik, the Ibar valley (from the vicinity of Trepča and So~anica, Ritopek

  11. A Quadrantic Bias in Prefrontal Representation of Visual-Mnemonic Space.

    Science.gov (United States)

    Leavitt, Matthew L; Pieper, Florian; Sachs, Adam J; Martinez-Trujillo, Julio C

    2017-06-09

    Single neurons in primate dorsolateral prefrontal cortex (dLPFC) are known to encode working memory (WM) representations of visual space. Psychophysical studies have shown that the horizontal and vertical meridians of the visual field can bias spatial information maintained in WM. However, most studies and models have tacitly assumed that dLPFC neurons represent mnemonic space homogenously. The anatomical organization of these representations has also eluded clear parametric description. We investigated these issues by recording from neuronal ensembles in macaque dLPFC with microelectrode arrays while subjects performed an oculomotor delayed-response task. We found that spatial WM representations in macaque dLPFC are biased by the vertical and horizontal meridians of the visual field, dividing mnemonic space into quadrants. This bias is reflected in single neuron firing rates, neuronal ensemble representations, the spike count correlation structure, and eye movement patterns. We also found that dLPFC representations of mnemonic space cluster anatomically in a nonretinotopic manner that partially reflects the organization of visual space. These results provide an explanation for known WM biases, and reveal novel principles of WM representation in prefrontal neuronal ensembles and across the cortical surface, as well as the need to reconceptualize models of WM to accommodate the observed representational biases. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  12. Energy-resources map of the Circum-Pacific region, northeast quadrant, and explanatory notes

    Energy Technology Data Exchange (ETDEWEB)

    Drummond, K.J.

    1985-01-01

    The Circum-Pacific Map Project is a cooperative international effort designed to show the relation of known energy and mineral resources to the major geologic features of the Pacific basin and surrounding continental areas. The map of the Northeast Quadrant depicts known energy deposits from Alaska to northern Peru. This multicolored map is published at a scale of 1:10,000,000 and attempts to provide a unified overview of the energy resources of the northeast part of the Circum-Pacific region. In the notes, sedimentary basins containing giant oil and gas field (greater than 500 million barrels or 3 trillion cubic feet) are shown on page-sized maps together with relevant geologic and production data. Major oil and gas fields along the Pacific margin of North and South America (greater than 100 million barrels and 600 billion cubic feet) are shown on index maps. Additional information is presented on coal, oil sand, and geothermal convection systems. The geologic map alone is worth a look, because it synthesizes a wealth of geologic data for an extremely large area. The map and booklet are successful in portraying the broad scope of energy resources present in the region.

  13. Metastatic tumors to the jaw bones: retrospective analysis from an Indian tertiary referral center.

    Science.gov (United States)

    Muttagi, S S; Chaturvedi, P; D'Cruz, A; Kane, S; Chaukar, D; Pai, P; Singh, B; Pawar, P

    2011-01-01

    Being a tertiary referral center, we encounter the highest number of oral cancer patients in India, and there is direct involvement of the jaw bone in approximately 40% of these cases. There are no large case series from the Indian subcontinent on metastatic tumors to the jaw bones. With this retrospective analysis, we intend to estimate the incidence of this rare manifestation in the jaw bones in our patients and compare it with the available literature. All patients with biopsy proven metastatic disease involving jaw bones having complete clinical data were included. Nineteen out of 10,411 oral cancer patients who reported between the years 2000 and 2005 were included. Breast and thyroid malignancies (5/19 each) were commonest in the females to metastasize to the mandible, whereas in the males, there was no predominant site that resulted in jaw bone metastasis, although mandible was commonly affected. Neuroblastoma of adrenal gland metastasized to maxilla in the age group ranging from 4 months to 16 years. maxilla was the commonest jaw bone affected in this age group. in five cases, jaw bone was found to be the first site of metastasis. There is variation in the primary site that causes metastasis to the jaw bones depending on age, sex and geographic distribution. Jaw bone metastases are rare and can be the first site of metastasis. We get approximately four cases in a year with metastatic disease manifesting in the jaw bones. Metastasis to jaw bone is associated with poor prognosis.

  14. Bisphosphonate-related osteonecrosis of the jaw in a multiple myeloma patient: A case report with characteristic radiographic features

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Do; Kwon, Kyung Hwan [College of Dentistry, Wonkwang University, Iksan (Korea, Republic of); Park, Moo Rim [Dept. of Internal Medicine, School of Medicine, Wonkwang University, Iksan (Korea, Republic of)

    2015-09-15

    A 59-year-old male who had suffered from multiple myeloma for nine years and had been administered bisphosphonates for seven years visited a dental hospital for pain relief due to extensive caries in his left maxillary molars. The molars were extracted, leaving an exposed wound for three months. The radiograph showed sequestra formation and irregular bone destruction in the left maxilla. Sudden pain and gingival swelling in the right mandibular molar area occurred six months later. The interseptum of the right lower second molar was observed to be necrotic during surgery. These findings coincided with the features of bisphosphonate-related osteonecrosis of the jaw (BRONJ). In this case, the long intravenous administration of bisphosphonates and tooth extraction were likely the etiologic factors of BRONJ in a patient with multiple myeloma; moreover, the bilateral occurrence of BRONJ is a characteristic feature.

  15. Bisphosphonate-related osteonecrosis of the jaw in a multiple myeloma patient: A case report with characteristic radiographic features

    International Nuclear Information System (INIS)

    Lee, Byung Do; Kwon, Kyung Hwan; Park, Moo Rim

    2015-01-01

    A 59-year-old male who had suffered from multiple myeloma for nine years and had been administered bisphosphonates for seven years visited a dental hospital for pain relief due to extensive caries in his left maxillary molars. The molars were extracted, leaving an exposed wound for three months. The radiograph showed sequestra formation and irregular bone destruction in the left maxilla. Sudden pain and gingival swelling in the right mandibular molar area occurred six months later. The interseptum of the right lower second molar was observed to be necrotic during surgery. These findings coincided with the features of bisphosphonate-related osteonecrosis of the jaw (BRONJ). In this case, the long intravenous administration of bisphosphonates and tooth extraction were likely the etiologic factors of BRONJ in a patient with multiple myeloma; moreover, the bilateral occurrence of BRONJ is a characteristic feature

  16. An EPID based method for efficient and precise asymmetric jaw alignment quality assurance

    International Nuclear Information System (INIS)

    Clews, Luke; Greer, Peter B.

    2009-01-01

    Purpose: The aim of this work was to investigate the use of amorphous silicon electronic portal imaging devices (EPIDs) for regular quality assurance of linear accelerator asymmetric jaw junctioning. Methods: The method uses the beam central axis position on the EPID measured to subpixel accuracy found from two EPID images with 180 degree sign opposing collimator angles. Individual zero jaw position (''half-beam blocked'') images are then acquired and the jaw position precisely determined for each using penumbra interpolation. The accuracy of determining jaw position with the EPID method was measured by translating a block (simulating a jaw) by known distances, using a translation stage, and then measuring each translation distance with the EPID. To establish the utility of EPID based junction dose measurements, radiographic film measurements of junction dose maxima/minima as a function of jaw gap/overlap were made and compared to EPID measurements. Using the method, the long-term stability of zero jaw positioning was assessed for four linear accelerators over a 1-1.5 yr time period. The stability at nonzero gantry angles was assessed over a shorter time period. Results: The accuracy of determining jaw translations with the method was within 0.14 mm found using the translation stage [standard deviation (SD) of 0.037 mm]. The junction doses measured with the EPID were different from film due to the nonwater equivalent EPID scattering properties and hence different penumbra profile. The doses were approximately linear with gap or overlap, and a correction factor was derived to convert EPID measured junction dose to film measured equivalent. Over a 1 yr period, the zero jaw positions at gantry zero position were highly reproducible with an average SD of 0.07 mm for the 16 collimator jaws examined. However, the average jaw positions ranged from -0.7 to 0.9 mm relative to central axis for the different jaws. The zero jaw position was also reproducible at gantry 90

  17. Effects of increased occlusal vertical dimension on the jaw-opening reflex in adult rats.

    Science.gov (United States)

    Makiguchi, Mio; Funaki, Yukiha; Kato, Chiho; Okihara, Hidemasa; Ishida, Takayoshi; Yabushita, Tadachika; Kokai, Satoshi; Ono, Takashi

    2016-12-01

    Malocclusion with deep overbite and facial esthetics improve when facial height is intentionally increased during orthodontic extrusion of the posterior teeth. Thus, a better understanding of post-treatment stability of increased occlusal vertical dimension (iOVD) in adult patients is important. We focused on the jaw-opening reflex (JOR), which plays an important role in the control of jaw movements during mastication, and investigated the effects of iOVD on the JOR in rats with an electrophysiological technique. One hundred and twenty 13-week-old male Wistar rats were randomly divided into control and experimental groups. Rats in the experimental group received a 2-mm buildup of composite resin on the maxillary molars at 13 weeks of age. The JOR was induced by low-intensity electrical stimulation of the left inferior alveolar nerve. The electromyographic responses were recorded from the digastric muscle at 13, 14, 15, 17, 19, and 23 weeks of age. JOR properties including latency, duration, and peak-to-peak amplitude were measured and compared between the groups. The latency of the JOR was significantly longer and the peak-to-peak amplitude was significantly smaller in the experimental group than in the control group from 14 to 19 weeks of age, while the reflex duration was not significantly different. Intra-group comparisons of the latency and peak-to-peak amplitudes among rats 14-19 weeks of age were significantly different between the experimental group and the control group. iOVD affected the latency and amplitude of the JOR but not the duration. The JOR adapted after 10 weeks of iOVD. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. [Stability of phonetics to determine the horizontal jaw relation in healthy adults].

    Science.gov (United States)

    Zhang, Xixi; Liu, Jianzhang; Tan, Jian-guo; Yang, Yang; Xu, Jun

    2015-10-01

    The aim of this study was to compare the mandibular position when speaking with the intercuspal position and to check the stability of phonetics when determining the horizontal jaw relation in healthy adults. A total of 19 healthy volunteers were recruited. Seven Chinese letters, namely, /xi/, /er/, /yi/, /ci/, /mi/, /ni/, and /ri/, were chosen in the test. O-bite was used to record the mandibular position when speaking these letters. A full-adjusted articulator was used to find the mandibular position during speech, and the mandibular position was measured using a vernier caliper. The mandibular position during speech with intercuspal position was compared in both anterior-posterior and left-right directions of the horizontal plane. Multi-factor analysis of variance was conducted for the statistical analysis of the effect of objects and letters on the mandibular position. 1) The mandibular position was in front of the intercuspal occlusion position when speaking all seven letters, and almost no deviation was observed in the left and right directions (the mandibular position value of 82% was in the range of 0.5 mm). 2) Different objects had different mandibular positions during speech, whereas different letters did not. The distance between the centric relation position and the intercuspal position had a positive correlation with the range of the mandibular position during speech. The mandibular position was in front of the intercuspal position when speaking all seven words in the test. In the same object, the mandibular position was stable during speech.

  19. The large-scale magnetic field in the fourth Galactic quadrant

    Science.gov (United States)

    Nota, T.; Katgert, P.

    2010-04-01

    Aims: We have re-examined the published rotation measures (RMs) of extragalactic point sources and pulsars with |b| corrupted” by an intervening supernova remnant. We modeled RM(l), the longitude dependence of RM of the unaffected extragalactic sources and pulsars. We assumed several geometries for the large-scale field. All but one of those are based on logarithmic spiral arms (with various pitch angles and widths), while one has circular symmetry. We also made different assumptions about the large-scale ne-distribution. Results: The data suggest the following generic behaviour of the large-scale field in the 4th Galactic quadrant. The field is most likely organized along logarithmic spiral arms and shows two significant reversals: from the Norma arm (CCW field) to the Norma-Crux interarm region (CW field), and from the Norma-Crux interarm region to the Crux arm (CCW field). The present data do not constrain the field in and beyond the Crux-Carina interarm region. Although the models give a good description of the global character of RM(l), individual RM-estimates deviate by typically 15 times their measurement errors. We argue that these large deviations are most likely due to the “small-scale” field that dominates on scales of up to several hundred pc. Conclusions: The picture that emerges is thus of a field that has significant structure on smaller scales, but for which the average values in arms and interarm regions are nevertheless well-defined. In addition, this smaller-amplitude large-scale field appears to reverse at each arm-interarm boundary that we can study with the present data. We briefly discuss the link between these results and theoretical predictions.

  20. Properties of five low-contrast open clusters in the third quadrant

    Science.gov (United States)

    Bica, E.; Bonatto, C.

    2005-11-01

    We derive photometric, structural and dynamical evolution-related parameters of five as yet unstudied low-contrast open clusters located in the third quadrant using 2MASS data. The target clusters are Czernik 31, Czernik 32, Haffner 9, Haffner 11 and Trumpler 13. We apply a statistical field-star decontamination procedure to infer on the intrinsic colour-magnitude diagram (CMD) morphology which is critical for such low-contrast objects. Consequently, it became possible to derive accurate reddening, age, distance from the Sun and Galactocentric distance for the five clusters. In the structural and luminosity/mass-function analyses we apply a colour-magnitude filter which encompasses the cluster evolutionary CMD sequences and excludes stars with discrepant colours. Using this procedure we derive core and limiting radii, mass function (MF) slope, total mass, mass density and relaxation time. We derive ages in the range 140-1100 Myr, Galactocentric distances within 7.7-11.4 kpc, and total masses within 360-2900 M_⊙. Reflecting large-scale mass segregation, the MF slope in the core is significantly flatter than that in the halo of the five clusters. Although some of the present clusters are relatively younger than the Gyr-old clusters, they present evidence of advanced dynamical evolution. This kind of study has become possible because of the photometric uniformity and spatial coverage of 2MASS which allows a proper subtraction of the field-star contamination on the target CMDs. The present study indicates that low-contrast clusters can be studied with 2MASS, particularly after field-star subtraction, which is important since most of the unstudied open clusters belong to this class.

  1. BISPHOSPHONATE-RELATED OSTEONECROSIS OF THE JAW AND DENTAL IMPLANTS

    Directory of Open Access Journals (Sweden)

    Ala Hassan A. Qamheya

    2016-01-01

    Full Text Available Bisphosphonate (BP is one of the possible riskfactors in the osteonecrosis of the jaw (ON J. Surgical interventions during or after the course of treatment by using BPs may expose the patient under this risk. Animal studies, human studies, case reports, and systematic reviews are used to show the relationship between the use of bisphosphonates and dental implants. In this review data about bisphosphonaterelated osteonecrosis of the jaw (BRON J: incidence, prevention and treatment modalities for the patients who are scheduled for dental implant treatment plan and who have been already treated by dental implants will be investigated. Various views for the relationship between dental implants and bisphosphonates will be analyzed depending on the multifactors: duration, route of uptake, dosage of the drug and patient’s other medications that affect the effects of bisphosphonate. All patients treated with this drug must be informed about the risk of implant loss or possibility of osteonecrosis.

  2. Oroantral fistula from bisphosphonate induced osteonecrosis of the jaw

    Directory of Open Access Journals (Sweden)

    Henry Sharp

    2010-07-01

    Full Text Available Bisphosphonates like alendronic acid, disodium etidronate, and risedronate are effective for preventing postmenopausal and corticosteroid induced osteoporosis. They are also useful in the treatment of Paget’s disease, hypercalcaemia of malignancy and in bony metastases. However osteonecrosis of the jaw has been reported following intravenous bisphosphonate use and rarely in those taking them orally.Increasingly, oroantral fistulae have been shown to occur as sequelae of bisphosphonate-induced osteonecrosis of the jaw and this case report highlights a patient that presented to our ENT department and required sinus surgery in collaboration with maxillofacial surgeons.This case report aims to raise awareness among ENT surgeons to these patients on bisphosphonates that could present to them with sinus disease from oroantral fistulae. There is an on-going audit in the maxillofacial community on this emerging trend.

  3. Monitoring of infant feeding behavior using a jaw motion sensor.

    Science.gov (United States)

    Farooq, Muhammad; Chandler-Laney, Paula C; Hernandez-Reif, Maria; Sazonov, Edward

    2015-01-01

    Rapid weight gain during infancy increases the risk of obesity. Given that infant feeding may contribute to rapid weight gain, it would be useful to develop objective tools which can monitor infant feeding behavior. This paper presents an objective method for examining infant sucking count during meals. A piezoelectric jaw motion sensor and a video camera were used to monitor jaw motions of 10 infants during a meal. Videotapes and sensor signals were annotated by two independent human raters, counting the number of sucks in each 10 second epoch. Annotated data were used as a gold standard for the development of the computer algorithms. The sensor signal was de-noised and normalized prior to computing the per-epoch sucking counts. A leave-one-out cross-validation scheme resulted in a mean error rate of -9.7% and an average intra-class correlation coefficient value of 0.86 between the human raters and the algorithm.

  4. The earliest herbivorous marine reptile and its remarkable jaw apparatus.

    Science.gov (United States)

    Chun, Li; Rieppel, Olivier; Long, Cheng; Fraser, Nicholas C

    2016-05-01

    Newly discovered fossils of the Middle Triassic reptile Atopodentatus unicus call for a radical reassessment of its feeding behavior. The skull displays a pronounced hammerhead shape that was hitherto unknown. The long, straight anterior edges of both upper and lower jaws were lined with batteries of chisel-shaped teeth, whereas the remaining parts of the jaw rami supported densely packed needle-shaped teeth forming a mesh. The evidence indicates a novel feeding mechanism wherein the chisel-shaped teeth were used to scrape algae off the substrate, and the plant matter that was loosened was filtered from the water column through the more posteriorly positioned tooth mesh. This is the oldest record of herbivory within marine reptiles.

  5. Effect of Repeated Food Morsel Splitting on Jaw Muscle Control

    DEFF Research Database (Denmark)

    A, Kumar; Svensson, Krister G; Baad-Hansen, Lene

    2014-01-01

    Mastication is a complex motor task often initiated by splitting of the food morsel between the anterior teeth. Training of complex motor tasks has consistently been shown to trigger neuroplastic changes in corticomotor control and optimization of muscle function. It is not known if training...... and repeated food morsel splitting lead to changes in jaw muscle function. Objective: To investigate if repeated splitting of food morsels in participants with natural dentition changes the force and jaw muscle electromyographic (EMG) activity. Methods: Twenty healthy volunteers (mean age = 26.2 ± 3.9 years......) participated in a single one-hour session divided into six series. Each series consisted of ten trials of a standardized behavioral task (total of 60 trials). The behavioral task was to hold and split a food morsel (8 mm, 180 mg placebo tablet) placed on a bite force transducer with the anterior teeth...

  6. Bisphosphonate-related osteonecrosis of the jaw: An insight

    Directory of Open Access Journals (Sweden)

    Shalini Kapoor

    2013-01-01

    Full Text Available Bisphosphonates are potent inhibitors of osteoclast activity that reduce bone turnover and re-establish the balance between bone resorption and formation. They are effective in multiple clinical settings including postmenopausal osteoporosis, low bone mass in men, and drug-induced bone loss. Bisphosphonate-associated osteonecrosis of jaws (BRONJ may result in serious oral complications, such as osteomyelitis and chronic exposure of necrotic bone. Dentists must be familiar with this disorder and pay special attention to all patients on bisphosphonate therapy due to their defective osteoclast function and reduced osseous tissue vascularity, leading to impaired wound healing and progressive necrosis of jaw bones. The purpose of this article is to review the history and pathogenesis of BRONJ, provide guidance to dentists on possible measures to prevent and manage patients with BRONJ.

  7. Fibrous dysplasia of the jaws: a case report.

    Science.gov (United States)

    Chindia, M L

    1991-04-01

    This article reviews the present clinical, radiographic and histologic features of fibrous dysplastic lesions of the jaws. A case is presented of an apparently reactivated fibrous dysplastic jaw lesion, with evidence of cystic degeneration, in a 33-year-old female school-teacher who was first seen at the Department of Dental Surgery, University of Nairobi in March 1986. The dilemma in the management of fibrous dysplasia is reviewed and discussed. It is noted that while conservative surgical procedures remain the treatment of choice, situations arise where tremendous tissue activity would require early intervention by numerous cosmetic surgical shaving procedures. The present case, however, offers a unique management challenge due to the occurrence of extensive cystic degeneration in the mandible.

  8. Fast phase retrieval with four-quadrant analysis in phase-shifting interferometry with blind phase shifts

    Science.gov (United States)

    Xu, Yuanyuan; Wang, Yawei; Han, Hao; Liu, Jingye; Ji, Ying; Jin, Weifeng; Xu, Xiaoqing

    2018-01-01

    Phase-shifting interferometry (PSI) is one of the most effective techniques in optical measurement, in which phase retrieval with high efficiency is an important procedure. In this paper, a simple non-iterative method is proposed to extract the generalized phase shift with the four-quadrant analysis in three-frame PSI. In this method, the possible value of the phase shift is firstly worked out with the inner product algorithm, and then a criterion is put forward to accurately determine its principal value within the range [ 0 , 2 π ] , based on the change relationship of the interference wave vector in four quadrants. Thus, this method provides a possible method to solve the uncertainty of phase shift existing in some common algorithms. Subsequently, the phase can be retrieved easily without any other measurements. Both simulation and experimental results have fully proved the feasibility and high accuracy of the method. Moreover, it works well on open- and closed-fringed patterns.

  9. Diagnosis of Upper-Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of APTA.

    Science.gov (United States)

    Levenhagen, Kimberly; Davies, Claire; Perdomo, Marisa; Ryans, Kathryn; Gilchrist, Laura

    2017-07-01

    The Oncology Section of APTA developed a clinical practice guideline to aid the clinician in diagnosing secondary upper-quadrant cancer-related lymphedema. Following a systematic review of published studies and a structured appraisal process, recommendations were written to guide the physical therapist and other health care clinicians in their diagnostic process. Overall, clinical practice recommendations were formulated on the basis of the evidence for each diagnostic method and were assigned a grade based on the strength of the evidence for different patient presentations and clinical utility. In an effort to make these clinically applicable, recommendations were based on the characteristics as to the location and stage of a patient's upper-quadrant lymphedema.

  10. Role of radiology in central hemangioma of jaws

    OpenAIRE

    Jindal, Sanjeev Kumar; Sheikh, Soheyl; Singla, Anshu; Puri, Nidhi

    2010-01-01

    Central hemangioma, a bone destructive lesion, is a benign tumor. Hemangiomas of jaws are rare entity and produ- ces many different radiographic images. Radiographic differential diagnosis includes osteosarcoma, fibrous dysplasia, central giant cell granuloma, ameloblastoma, odontogenic myxoma, multiple myeloma, dentigerous cyst and aneurysmal bone cyst. Since it involves proliferation of blood vessels so aspiration or biopsy of such lesions can lead to severe hemorrhage which can ...

  11. Failure analysis of vise jaw holders for hacksaw machine

    Directory of Open Access Journals (Sweden)

    Essam Ali Al-Bahkali

    2018-01-01

    Full Text Available Failure analysis in mechanical components has been investigated in many studies in the last few years. Failure analysis and prevention are important functions in all engineering disciplines. Materials engineers are often the lead role in the analysis of failures, where a component or product fails in service or if a failure occurs during manufacturing or production processing. In any case, one must determine the cause of the failure to prevent future occurrences and/or to improve the performance of the device, component or structure. For example, the vise jaw holders of hacksaws can break due to accidental heavy loads or machine misuse. The parts that break are the stationary and movable vise jaw holders and the connecter power screw between the holders. To investigate the failure of these components, a three-dimensional finite element model for stress analysis was performed. First, the analysis identified the broken components of the hacksaw machine. In addition, the type of materials of the broken parts was identified, a CAD model was built, and the hacksaw mechanism was analyzed to determine the accurate applied loads on the broken parts. After analyzing the model using Abaqus CAE software, the results showed that the location of the high stresses was identical with the high-stress locations in the original, broken parts. Furthermore, the power screw was subjected to a high load, which deformed the power screw. Also, the stationary vise jaw holder was broken by impact because it was not touched by the power screw until the movable vise jaw holder broke. A conclusion is drawn from the failure analysis and a way to improve the design of the broken parts is suggested.

  12. Bisphosphonates and jaw osteonecrosis in patients with advanced breast cancer.

    Science.gov (United States)

    Sanna, G; Preda, L; Bruschini, R; Cossu Rocca, M; Ferretti, S; Adamoli, L; Verri, E; Franceschelli, L; Goldhirsch, A; Nolè, F

    2006-10-01

    In recent years, several cases of mandibular necrosis associated with long-term use of bisphosphonates have been reported. The estimated incidence varies from 1% to 4.6%. We conducted an observational study with the aim of determining the incidence of jaw osteonecrosis in advanced breast cancer patients with bone metastases under bisphosphonate treatment and to identify subjects at higher risk of developing this complication evaluating preclinical signs. We considered two groups of patients. All the patients complaining of odontostomatological symptoms underwent maxillary CT scan and maxillo-surgeon clinical examination. Asymptomatic patients were asked to perform a standard orthopantomography (OPT). From February 2005 to October 2005, we observed five patients with jaw bone necrosis (6%). Diagnosis was radiological and clinical. In two patients a confirmatory biopsy was performed. In the same time interval, OPTs were collected from 76 asymptomatic patients. Three OPTs revealed radiological features of suspicious mandibular necrosis. Maxillary CT scan confirmed the presence of an osteolityc area with signs of periosteal reaction. All the three patients were referred to maxillo-surgeon and two out of three patients underwent mandibular biopsy, but histopathological results were not conclusive. In our experience, the incidence of jaw bone necrosis in breast cancer patients seems to be higher than in other reports (6%). Radiological features of suspicious jaw necrosis were observed in three asymptomatic patients. We do not know how these findings should be considered. Anyway, standard OPT is a simple procedure, and may allow identification of periodontal conditions that in some way can predispose to the development of this uncommon event.

  13. [Chondrosarcoma of the jaw. A case localized to the mandible].

    Science.gov (United States)

    Oujilal, A; el Alami, M N; Lazrak, A; Jazouli, N; Kzadri, M

    2001-04-01

    Chondrosarcoma is a malignant cartilaginous tumor rarely found in the jaw bone. Tumor progression is slow with strong propensity to local recurrence after surgical removal. The prognosis is poor and depends on the degree of differentiation and the quality of the resection. We report a case of mandibular chondrosarcoma that exhibited particularly massive extension to soft tissue. We discuss the epidemiology, diagnosis, treatment and follow-up of these tumors.

  14. Estimation of jaw-opening forces in adults.

    Science.gov (United States)

    Brunton, P A; Loch, C; Waddell, J N; Bodansky, H J; Hall, R; Gray, A

    2018-02-01

    To estimate maximum jaw-opening forces in healthy participants of diverse ancestry and to estimate whether opening forces are associated with sex, age and anthropometric parameters such as height, weight and BMI. One hundred and forty-nine participants aged 20-60 years with overall good oral and general health. Exclusion criteria included myofascial or neck pain, symptomatic temporomandibular joint disorders (TMD), current orthodontic treatment or the absence of a natural dentition. Jaw-opening forces were measured with an adjustable rigid extra-oral device connected to a 1000 N load cell. Seven attempts were recorded, with 10 seconds interval. Median force values were obtained after discarding the first and last attempt. The height and weight of each participant were measured and recorded, alongside age, sex and ethnicity. Men had greater maximum opening force median values than women (P < .001). Median (IQR) values for women were 41.16 N (30.44) and 79.00 N for men (63.86). Jaw-opening force values were poorly associated with biological and anthropometric parameters. In this study, which included a large sample of participants of broad age range and from a demographically diverse background, jaw-opening force values were greater in males than in females; however, force values were poorly associated with biological and anthropometric parameters. Future studies should explore the potential of this method as a screening tool for TMJ disorders and other conditions. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  15. Description of the lower jaws of Baculites from the Upper Cretaceous U.S. Western Interior

    Science.gov (United States)

    Larson, Neal L.; Landman, Neil H.

    2017-03-01

    We report the discovery of lower jaws of Baculites (Ammonoidea) from the Upper Cretaceous U.S. Western Interior. In the lower Campanian Smoky Hill Chalk Member of the Niobrara Chalk of Kansas, most of the jaws occur as isolated elements. Based on their age, they probably belong to Baculites sp. (smooth). They conform to the description of rugaptychus, and are ornamented with coarse rugae on their ventral side. One specimen is preserved inside a small fecal pellet that was probably produced by a fish. Another specimen occurs inside in a crushed body chamber near the aperture and is probably in situ. Three small structures are present immediately behind the jaw and may represent the remains of the gills. In the lower Maastrichtian Pierre Shale of Wyoming, two specimens of Baculites grandis contain lower jaws inside their body chambers, and are probably in situ. In both specimens, the jaws are oriented at an acute angle to the long axis of the shell, with their anterior ends pointing toward the dorsum. One of the jaws is folded into a U-shape, which probably approximates the shape of the jaw during life. Based on the measurements of the jaws and the shape of the shell, the jaws could not have touched the sides of the shell even if they were splayed out, implying that they could not have effectively served as opercula. Instead, in combination with the upper jaws and radula, they constituted the buccal apparatus that collected and conveyed food to the esophagus.

  16. Diagnosis of Upper-Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of APTA

    OpenAIRE

    Levenhagen, Kimberly; Davies, Claire; Perdomo, Marisa; Ryans, Kathryn; Gilchrist, Laura

    2017-01-01

    Introduction: The Oncology Section of APTA developed a clinical practice guideline to aid the clinician in diagnosing secondary upper-quadrant cancer-related lymphedema. Methods: Following a systematic review of published studies and a structured appraisal process, recommendations were written to guide the physical therapist and other health care clinicians in their diagnostic process. Overall, clinical practice recommendations were formulated on the basis of the evidence for each diagnostic ...

  17. Jaw lesions associated with impacted tooth: A radiographic diagnostic guide

    Energy Technology Data Exchange (ETDEWEB)

    Motazavi, Hamed; Bharvand, Maryam [Dept. of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran (Iran, Islamic Republic of)

    2016-09-15

    This review article aimed to introduce a category of jaw lesions associated with impacted tooth. General search engines and specialized databases such as Google Scholar, PubMed, PubMed Central, MedLine Plus, Science Direct, Scopus, and well-recognized textbooks were used to find relevant studies using keywords such as 'jaw lesion', 'jaw disease', 'impacted tooth', and 'unerupted tooth'. More than 250 articles were found, of which approximately 80 were broadly relevant to the topic. We ultimately included 47 articles that were closely related to the topic of interest. When the relevant data were compiled, the following 10 lesions were identified as having a relationship with impacted tooth: dentigerous cysts, calcifying odontogenic cysts, unicystic (mural) ameloblastomas, ameloblastomas, ameloblastic fibromas, adenomatoid odontogenic tumors, keratocystic odontogenic tumors, calcifying epithelial odontogenic tumors, ameloblastic fibro-odontomas, and odontomas. When clinicians encounter a lesion associated with an impacted tooth, they should first consider these entities in the differential diagnosis. This will help dental practitioners make more accurate diagnoses and develop better treatment plans based on patients' radiographs.

  18. Fine-needle aspiration biopsy of intraosseous jaw lesions.

    Science.gov (United States)

    August, M; Faquin, W C; Ferraro, N F; Kaban, L B

    1999-11-01

    This study assessed diagnostic accuracy, determined reasons for error, and evaluated modifications to improve the reliability of fine-needle aspiration biopsy (FNAB) of primary jaw lesions. This was a retrospective review of 32 FNABs of intraosseous jaw lesions performed at the Massachusetts General and Children's Hospital between 1993 and 1998. A consistent, standardized technique was used, and each case was evaluated for 1) adequacy of cells to allow diagnosis, 2) presence of malignant cells, and 3) correlation between FNAB diagnosis and the final histopathology. Material obtained by FNAB was adequate for evaluation in 30 of 32 cases. No complications were reported. Malignant cells were found in 5 of 30 cases. FNAB diagnosis was confirmed by histopathology in all 5 of these specimens (100% accuracy). The FNAB diagnosis of benign lesions was confirmed in 17 of 25 cases (68%). The most common benign lesions were odontogenic cysts, ameloblastomas, and fibro-osseous and giant cell lesions. Incorrect diagnosis was related to lack of architectural context of the FNAB material, sampling of a nonrepresentative part of a large lesion, and inadequate quantity or quality of the aspirate. FNAB is a useful technique to distinguish between malignant and benign intraosseous jaw lesions. Its simplicity, suitability as an outpatient procedure, rapidity of interpretation, and minimal morbidity potentially make it the diagnostic tool of choice in the hospital setting.

  19. Role of FNAC in the diagnosis of intraosseous jaw lesions.

    Science.gov (United States)

    Goyal, Surbhi; Sharma, Sonal; Kotru, Mrinalini; Gupta, Neelima

    2015-05-01

    FNAC of intraosseous jaw lesions has not been widely utilized for diagnosis due to rarity and diversity of these lesions, limited experience and lack of well established cytological features. Aim of the study was to determine the role of FNAC in the diagnosis of intraosseous jaw swellings. 42 patients underwent FNAC over a period of 7 years (2007-2013), of which 37 (88.1%) aspirates were diagnostic. Histopathology correlation was available in 33 cases and diagnostic accuracy of FNAC was calculated. Lesions were categorized into inflammatory 3, cysts/hamartomas 15 and neoplasms 19. Mandibular and maxillary involvement was seen in 21 and 16 patients respectively. Of these, benign cysts and malignant lesions were commonest, accounting for 27% lesions (10 cases) each. One case of cystic ameloblastoma was misdiagnosed as odontogenic cyst on cytology. Overall, sensitivity and specificity of FNAC were 94.7% and 100% respectively with a diagnostic accuracy of 97.3%. Definitive categorization of giant cell lesions, fibro-osseous lesions, odontogenic tumors and cystic lesions was not feasible on FNAC. FNAC is a simple, safe and minimally invasive first line investigation which can render an accurate preoperative diagnosis of intraosseous jaw lesions, especially the malignant ones in the light of clinic-radiological correlation.

  20. Mechanical constraint from growing jaw facilitates mammalian dental diversity.

    Science.gov (United States)

    Renvoisé, Elodie; Kavanagh, Kathryn D; Lazzari, Vincent; Häkkinen, Teemu J; Rice, Ritva; Pantalacci, Sophie; Salazar-Ciudad, Isaac; Jernvall, Jukka

    2017-08-29

    Much of the basic information about individual organ development comes from studies using model species. Whereas conservation of gene regulatory networks across higher taxa supports generalizations made from a limited number of species, generality of mechanistic inferences remains to be tested in tissue culture systems. Here, using mammalian tooth explants cultured in isolation, we investigate self-regulation of patterning by comparing developing molars of the mouse, the model species of mammalian research, and the bank vole. A distinct patterning difference between the vole and the mouse molars is the alternate cusp offset present in the vole. Analyses of both species using 3D reconstructions of developing molars and jaws, computational modeling of cusp patterning, and tooth explants cultured with small braces show that correct cusp offset requires constraints on the lateral expansion of the developing tooth. Vole molars cultured without the braces lose their cusp offset, and mouse molars cultured with the braces develop a cusp offset. Our results suggest that cusp offset, which changes frequently in mammalian evolution, is more dependent on the 3D support of the developing jaw than other aspects of tooth shape. This jaw-tooth integration of a specific aspect of the tooth phenotype indicates that organs may outsource specific aspects of their morphology to be regulated by adjacent body parts or organs. Comparative studies of morphologically different species are needed to infer the principles of organogenesis.

  1. Imaging of jaw with dental CT software program: Normal Anatomy

    International Nuclear Information System (INIS)

    Kim, Myong Gon; Seo, Kwang Hee; Jung, Hak Young; Sung, Nak Kwan; Chung, Duk Soo; Kim, Ok Dong; Lee, Young Hwan

    1994-01-01

    Dental CT software program can provide reformatted cross-sectional and panoramic images that cannot be obtained with conventional axial and direct coronal CT scan. The purpose of this study is to describe the method of the technique and to identify the precise anatomy of jaw. We evaluated 13 mandibles and 7 maxillae of 15 subjects without bony disease who were being considered for endosseous dental implants. Reformatted images obtained by the use of bone algorithm performed on GE HiSpeed Advantage CT scanner were retrospectively reviewed for detailed anatomy of jaw. Anatomy related to neurovascular bundle(mandibular foramen, inferior alveolar canal, mental foramen, canal for incisive artery, nutrient canal, lingual foramen and mylohyoid groove), muscular insertion(mylohyoid line, superior and inferior genial tubercle and digastric fossa) and other anatomy(submandibular fossa, sublingual fossa, contour of alveolar process, oblique line, retromolar fossa, temporal crest and retromolar triangle) were well delineated in mandible. In maxilla, anatomy related to neurovascular bundle(greater palatine foramen and groove, nasopalatine canal and incisive foramen) and other anatomy(alveolar process, maxillary sinus and nasal fossa) were also well delineated. Reformatted images using dental CT software program provided excellent delineation of the jaw anatomy. Therefore, dental CT software program can play an important role in the preoperative assessment of mandible and maxilla for dental implants and other surgical conditions

  2. Imaging of jaw with dental CT software program: Normal Anatomy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myong Gon; Seo, Kwang Hee; Jung, Hak Young; Sung, Nak Kwan; Chung, Duk Soo; Kim, Ok Dong [School of Medicine, Taegu Catholic University, Taegu (Korea, Republic of); Lee, Young Hwan [Taegu Armed Forces General Hospital, Taegu (Korea, Republic of)

    1994-07-15

    Dental CT software program can provide reformatted cross-sectional and panoramic images that cannot be obtained with conventional axial and direct coronal CT scan. The purpose of this study is to describe the method of the technique and to identify the precise anatomy of jaw. We evaluated 13 mandibles and 7 maxillae of 15 subjects without bony disease who were being considered for endosseous dental implants. Reformatted images obtained by the use of bone algorithm performed on GE HiSpeed Advantage CT scanner were retrospectively reviewed for detailed anatomy of jaw. Anatomy related to neurovascular bundle(mandibular foramen, inferior alveolar canal, mental foramen, canal for incisive artery, nutrient canal, lingual foramen and mylohyoid groove), muscular insertion(mylohyoid line, superior and inferior genial tubercle and digastric fossa) and other anatomy(submandibular fossa, sublingual fossa, contour of alveolar process, oblique line, retromolar fossa, temporal crest and retromolar triangle) were well delineated in mandible. In maxilla, anatomy related to neurovascular bundle(greater palatine foramen and groove, nasopalatine canal and incisive foramen) and other anatomy(alveolar process, maxillary sinus and nasal fossa) were also well delineated. Reformatted images using dental CT software program provided excellent delineation of the jaw anatomy. Therefore, dental CT software program can play an important role in the preoperative assessment of mandible and maxilla for dental implants and other surgical conditions.

  3. Evolution of the vertebrate jaw from developmental perspectives.

    Science.gov (United States)

    Kuratani, Shigeru

    2012-01-01

    Attainment of the biting jaw is regarded as one of the major novelties in the early history of vertebrates. Based on a comparison between lamprey and gnathostome embryos, evolutionary developmental studies have tried to explain this novelty as changes in the developmental patterning of the mandibular arch, the rostralmost pharyngeal arch, at the molecular and cellular levels. On the other hand, classical theories in the field of comparative morphology assumed the involvement of hypothetical premandibular arch(es) that ancestral animals would have possessed rostral to the mandibular arch, in the transition from agnathan to gnathostome states. These theories are highly biased toward the segmental scheme of the vertebrate head, and the concept of premandibular "arches" is no longer accepted by the current understanding. Instead, the premandibular domain has now become of interest in the understanding of cranial development, especially in its rostral part. As newer theories that consider involvement of the premandibular domain, the neoclassical and heterotopy theories are here compared from evolutionary developmental perspectives, in conjunction with the development of nasal and hypophyseal placodes, in the context of the evolutionary acquisition of the jaw. Given recent advances in understanding of the lamprey development, evolution of the Dlx code is also discussed together with the evolutionary scenario of jaw acquisition. © 2012 Wiley Periodicals, Inc.

  4. Treatment of enucleated odontogenic jaw cysts: a systematic review.

    Science.gov (United States)

    Buchbender, Mayte; Neukam, Friedrich W; Lutz, Rainer; Schmitt, Christian M

    2017-12-29

    In this systematic review, we aimed to assess the impact of filling or not filling enucleated odontogenic jaw cysts on bony defect consolidation. In terms of filling, we aimed to assess which is the best filling material based on current evidence. An electronic search was performed using PubMed, Embase, and MEDLINE databases with the logical operators: "odontogenic cysts" AND "jaw cysts" AND "treatment AND therapy." Thirteen studies with primary enucleation (6 with filling and 7 without filling) were included. In terms of filling, either synthetic bone substitutes or autologous bone were used. The primary outcome was bony regeneration judged by radiographic follow-up measurements. Two-dimensional (2-D) radiographic follow-up measurements (densitometry) revealed a bone density increase and comparable bone regeneration in both groups. Because of the low number of studies and the heterogeneity of the included data, evidence-based treatment recommendations cannot be given at this time. Also, outcomes based on 2-D measurements should be interpreted with caution. However, the following factors are suggested as having an impact on bony defect consolidation: defect size, defect configuration, the preservation of the periosteum, and localization (upper or lower jaw). Prospective comparable clinical studies with a 3-dimensional follow-up are needed. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. The feasibility of immediately loading dental implants in edentulous jaws

    Science.gov (United States)

    2016-01-01

    Purpose Immediate loading of dental implants has been proved to be feasible in partially edentulous jaws. The purpose of this retrospective investigation was to assess the feasibility of immediately loading dental implants in fully edentulous jaws. Methods A total of 24 patients aged between 53 and 89 years received a total of 154 implants in their edentulous maxillae or mandibles. Among the implants, 45 were set in fresh extracted sockets and 109 in consolidated alveolar bones. The implants were provisionally managed with chair-side made provisional resin bridges and exposed to immediate loading. Implants were followed up for 1–8 years, including radiographic imaging. Marginal bone levels were evaluated based on radiographic imaging. Results A total of 148 out of the 154 implants survived over the follow-up period of 1 to 8 years, giving a survival rate of 96%. The time or region of the implantation, the pre-implant augmentation, and the length and diameter of the implants had no statistically significant influence on the survival or the success rate. The marginal bone level remained stable with only minimal loss of 0.3 mm after 60 months of loading. Conclusions Within the limitations of this study, immediate loading is feasible for dental implants in edentulous jaws. PMID:27588213

  6. Jaw lesions associated with impacted tooth: A radiographic diagnostic guide

    International Nuclear Information System (INIS)

    Motazavi, Hamed; Bharvand, Maryam

    2016-01-01

    This review article aimed to introduce a category of jaw lesions associated with impacted tooth. General search engines and specialized databases such as Google Scholar, PubMed, PubMed Central, MedLine Plus, Science Direct, Scopus, and well-recognized textbooks were used to find relevant studies using keywords such as 'jaw lesion', 'jaw disease', 'impacted tooth', and 'unerupted tooth'. More than 250 articles were found, of which approximately 80 were broadly relevant to the topic. We ultimately included 47 articles that were closely related to the topic of interest. When the relevant data were compiled, the following 10 lesions were identified as having a relationship with impacted tooth: dentigerous cysts, calcifying odontogenic cysts, unicystic (mural) ameloblastomas, ameloblastomas, ameloblastic fibromas, adenomatoid odontogenic tumors, keratocystic odontogenic tumors, calcifying epithelial odontogenic tumors, ameloblastic fibro-odontomas, and odontomas. When clinicians encounter a lesion associated with an impacted tooth, they should first consider these entities in the differential diagnosis. This will help dental practitioners make more accurate diagnoses and develop better treatment plans based on patients' radiographs

  7. Children Presenting at the Emergency Department With Right Lower Quadrant Pain

    Directory of Open Access Journals (Sweden)

    Chien-Heng Lin

    2009-01-01

    Full Text Available Right lower quadrant (RLQ pain is a common complaint in children presenting at emergency departments. This study analyzed the etiologies of RLQ pain, and compared the clinical presentations, laboratory test results and imaging findings in patients with appendicitis with those in other groups of patients. We also investigated if active observation resulted in delayed diagnosis, to the detriment of patients. Medical records for the period January 2006 to July 2006 were reviewed for children (age < 18 years who presented to the emergency department of one medical center, complaining of RLQ pain. Out of a total of 100 patients (age range: 2–17 years; mean: 11 years, 46 patients presented with only one symptom of RLQ pain, while 32 patients had ≥ 2 associated signs or symptoms, including fever, nausea/vomiting, diarrhea, or rebound tenderness. Imaging studies, including abdominal sonography and/or computed tomography, were performed in 73 patients; 44 underwent surgery for presumed appendicitis and one received surgery for a right paraduodenal hernia. Eleven patients underwent surgery because of peritoneal signs, and eight because of persistent or aggravated RLQ pain. Postoperative pathologic examinations revealed 53 cases of appendicitis, six normal appendices, and other morbidities (1 perforated peptic ulcer, 1 pelvic inflammatory disease, 1 ovarian cyst, 1 diverticulitis, and 1 right paraduodenal hernia. Thirty-three patients were discharged after several hours of observation (range: 0.5–18 hours; mean: 4 hours, and three patients were admitted for further observations. All were discharged without operation. There were significant differences in the incidences of fever (p = 0.004 and rebound tenderness (p = 0.019, and in white cell counts (p < 0.001, neutrophil percentages (p < 0.001, and C-reactive protein levels (p < 0.001 between patients with appendicitis and patients with other causes of RLQ pain. Clinical signs and symptoms, laboratory

  8. BISPHOSPHONATE-INDUCED OSTEONECROSIS OF THE JAW AND GUIDELINES FOR DIAGNOSIS, STAGING AND DENTAL MANAGEMENT: REVIEW

    OpenAIRE

    Santosh; Deepa; Sangmeshwar; Sridevi; Pallavi

    2014-01-01

    : Bisphosphonate-associated osteonecrosis of the jaw, often abbreviated as BON, BON of the jaw or even BRONJ, is a recently discovered dental phenomenon that may lead to surgical complication in the form of impaired wound healing following oral or periodontal surgery or endodontic therapy. 1 In 2003, the first reports describing osteonecrosis of the jaw in patients receiving bisphosphonates were published. About 95% of these cases occurred among cancer patients receivin...

  9. Sexual dimorphism in black jaw tiliapia (Sarotherodon melanotheron and banded jewelfish (Hemichromis fasciatus from the Great Kwa River, Calabar, Nigeria

    Directory of Open Access Journals (Sweden)

    Ibor Oju Richard

    2017-12-01

    Full Text Available In this study, the pattern and magnitude of sexual dimorphic differences have been investigated in black jaw tilapia (Sarotherodon melanotheron (n = 160; 74 males and 86 females and banded jewelfish (Hemichromis fasciatus (n = 120; 42 males and 78 females from the Great Kwa River, Calabar, Nigeria. Fish samples were collected between July and December 2015. Fourteen morphometric variables, including body weight, total length, standard length, body depth, cheek depth, pre-orbital length, postorbital length, pectoral fin length (right and left, pelvic fin length (right and left, head length, gonad weight, eye diameter and four meristic variables, including number of pectoral fins (right and left and number of pelvic fins (right and left, were taken using standard methods. Size-adjusted morphometric measurements subjected to step-wise discriminant function analysis were used to determine predictor variables to morphologically differentiate sexes for both species; magnitude of dimorphism between sexes was estimated using percentage classification accuracy of the discriminant function analysis. From the discriminant function analysis, the pectoral fin length and gonad weight positively contributed significantly to morphometric dimorphism (magnitude=69.2% in male and female S. melanotheron suggesting adaptation for reproductive function; while for H. fasciatus the body depth and standard length were important contributors to sexual dimorphism (magnitude=84.2% suggesting size dimorphism for aggressiveness, territorial behavior and improving swimming performance. Overall, our results indicate that the different magnitude of sexual dimorphism between the two species could be attributable to the type and functional role of sexual dimorphic traits.

  10. Size of lower jaw as an early indicator of skeletal class III development

    Directory of Open Access Journals (Sweden)

    Stojanović Zdenka

    2008-01-01

    Full Text Available Background/Aim. Malocclusion of skeletal class III is a complex abnormality, with a characteristic sagital position of the lower jaw in front of the upper one. A higher level of prognatism of the lower jaw in relation to the upper one can be the consequence of its excessive length. The aim of this study was to find the differences in the length of the lower jaw in the children with skeletal class III and the children with normal sagital interjaw relation (skeletal class I in the period of mixed dentition. Methods. After clinical and x-ray diagnostics, profile tele-x-rays of the head were analyzed in 60 examinees with mixed dentition, aged from 6 to 12 years. The examinees were divided into two groups: group 1 - the children with skeletal class III and group 2 - the children with skeletal class I. The length of the lower jaw, upper jaw and cranial base were measured. The proportional relations between the lengths measured within each group were established and the level of difference in the lengths measured and their proportions between the groups were estimated. Results. No significant difference between the groups was found in the body length, ramus and the total length of the lower jaw. Proportional relation between the body length and the length of the lower jaw ramus and proportional relation between the forward cranial base and the lower jaw body were not significantly different. A significant difference was found in proportional relations of the total length of the lower jaw with the total lengths of cranial base and the upper jaw and proportional relation of the length of the lower and upper jaw body. Conclusion. Of all the analyzed parameters, the following were selected as the early indicators of the development of skeletal class III on the lower jaw: greater total length of the lower jaw, proportional to the total lengths of cranial base and the upper jaw, as well as greater length of the lower jaw body, proportional to the length of

  11. Dentoskeletal Overjet Measurements of Iraqi Adult Sample with Different Skeletal Jaw Relationship

    Directory of Open Access Journals (Sweden)

    Shahbaa A Mohammed

    2017-11-01

    Full Text Available Background: Many attempts were done to develop a method that actually reflects the sagittal jaw discrepancies without depending on cranial landmarks or dental occlusion. This study aimed to use one of these methods (dentoskeletal overjet for assessing the sagittal jaw relationships of Iraqi adult sample with different skeletal jaw relationship. Materials and method: The sample consisted of 90 digital true lateral cephalometric radiographs of Iraqi individuals with no previous orthodontic treatment. Cephalometric analysis of skeletal sagittal jaw relationship -ANB angle, beta angle and Wits appraisal- will perform for everyone to divide the sample into three groups (skeletal class I, II, III for which the dentoskeletal overjet will be measured. All cephalometric measurements will be done using AutoCAD. Results: Descriptive statistics of all variables with different skeletal jaw relationship showed that mean values of dentoskeletal overjet were (1.15, 3.91 and –2.01 mm for skeletal class I, class II and class III jaw relationship respectively. Accurate reproducibility of dentoskeletal overjet in assessment of jaw skeletal relationship showed that the lowest value was for assessment of skeletal class III jaw relationship (73% and the value for assessment of both skeletal class I and class II was higher (93%. Conclusions: Dentoskeletal overjet could be utilized in accurate representation of skeletal jaw relationship.

  12. Prognosis of teeth in the line of jaw fractures.

    Science.gov (United States)

    Aulakh, Kamaldeep K; Gumber, Tejinder Kaur; Sandhu, Sumeet

    2017-04-01

    The decision as to whether teeth in the line of jaw fractures should be extracted or retained remains a controversial issue. The aim of this study was to assess the prognosis of teeth directly in the line of, and adjacent to, jaw fracture sites. The study consisted of 50 patients with facial fractures in the dentate region, the diagnosis of which was made on the basis of clinical and radiographic examinations. A total of 124 teeth were present in 69 fracture sites (50 patients), of which 89 teeth were evaluated both, clinically (tooth mobility, pocket depth, pulp sensibility) and with periapical radiographs (degree of fracture displacement, marginal bone loss, root resorption). The results revealed that 61.9% of teeth in directly in the line of fractures showed no response to electric pulp testing compared with 48.9% teeth adjacent to fractures. The maximum frequency of non-responsive teeth was observed in Type I fractures followed by Type II fractures. Response to pulp tests was highly significant at postoperative 3- and 6-month periods (Wilcoxon's test). There was continuous reduction in the measurement for mean pocket depth at both test and control sites of teeth. The measurement of marginal bone levels of teeth in the line of fractures revealed a significant reduction (P fracture sites, the mean marginal bone levels of control site and test sites were not significant at any time interval. There was no difference in postoperative complications pertaining to whether the tooth at the fracture site was extracted or retained. Teeth in line of jaw fractures should not be removed on a prophylactic basis and should be followed up clinically and radiographically to determine any treatment needs. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Jaw position uncertainty and adjacent fields in breast cancer radiotherapy.

    Science.gov (United States)

    Hedin, Emma; Bäck, Anna; Chakarova, Roumiana

    2015-11-08

    Locoregional treatment of breast cancer involves adjacent, half blocked fields matched at isocenter. The objective of this work is to study the dosimetric effects of the uncertainties in jaw positioning for such a case, and how a treatment planning protocol including adjacent field overlap of 1 mm affects the dose distribution. A representative treatment plan, involving 6 and 15 photon beams, for a patient treated at our hospital is chosen. Monte Carlo method (EGSnrc/BEAMnrc) is used to simulate the treatment. Uncertainties in jaw positioning of ± 1 mm are addressed, which implies extremes in reality of 2 mm field gap/overlap when planning adjacent fields without overlap and 1 mm gap or 3 mm overlap for a planning protocol with 1 mm overlap. Dosimetric parameters for PTV, lung and body are analyzed. Treatment planning protocol with 1 mm overlap of the adjacent fields does not considerably counteract possible underdosage of the target in the case studied. PTV-V95% is for example reduced from 95% for perfectly aligned fields to 90% and 91% for 2 mm and 1 mm gap, respectively. However, the risk of overdosage in PTV and in healthy soft tissue is increased when following the protocol with 1 mm overlap. A 3 mm overlap compared to 2 mm overlap results in an increase in maximum dose to PTV, PTV-D2%, from 113% to 121%. V120% for 'Body-PTV' is also increased from 5 cm(3) to 14 cm(3). A treatment planning protocol with 1 mm overlap does not considerably improve the coverage of PTV in the case of erroneous jaw positions causing gap between fields, but increases the overdosage in PTV and doses to healthy tissue, in the case of overlapping fields, for the case investigated.

  14. [Juvenile ossifying fibroma: a misgiving tumor of the jaws].

    Science.gov (United States)

    Odin, Guillaume; Benchetrit, Maxime; Raybaud, Hélène; Balaguer, Thierry; Soler, Christine; Michiels, Jean-François

    2012-02-01

    Juvenile ossifying fibroma is a rare benign tumour of childhood. It is hardly distinguishable from others fibro-osseous lesions because of their overlapping microscopic features. Juvenile variant of ossifying fibroma may be mistaken for malignancy, particularly osteosarcoma. Radiology is central to their diagnosis because of the very limited nature of the tumour. Microscopically, the lack of cytologic atypia or abnormal mitosis, and the presence of bone maturation or cementum deposits are consistent with an ossifying fibroma. This entity should be kept in mind regarding any bone lesion jaws in children. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  15. Multiple fibromyxomas of the jaws: A case report.

    Science.gov (United States)

    Zayet, Mohamed Khalifa; Eiid, Salma Belal

    2014-09-01

    Fibromyxoma of the jaw is a rare benign mesenchymal odontogenic tumor with locally aggressive behavior. In the present report, a 13-year-old female patient presented to our university hospital with delayed eruption of some of her teeth. A panoramic radiograph taken at the initial examination revealed four pericoronal radiolucencies related to the four third molars. Thereafter, a magnetic resonance imaging (MRI) examination was performed. After the surgical removal of these molars, the microscopic examination diagnosed the four lesions as fibromyxomas. Here, we have discussed the clinical, panoramic radiography, MRI, and histopathological findings of the case.

  16. Self-Controlling Rig for Jaw Crusher Assembly

    OpenAIRE

    Saurabh Jadhav; Anup Pawar

    2017-01-01

    The aim of the work is to develop a method for easy assembly of the bearing in the housing by standardized way. The assembly of bearing should take place on the atomized set up. Based on this method a assembly setup was constructed which enables to assembly of the shaft with bearing of different models of jaw crusher. First tests were done with manual alignment and it shows that with proper alignment shaft assembly is very easy operation and also safe. Results of those tests show that the dev...

  17. Frequency of third molar agenesis: relation to jaw size

    OpenAIRE

    Botina, Cristian Julián; Rodríguez, Luisa Fernanda; Cepeda, Eugenia Catalina; Zabala, Diego Fernando; González-Colmenares, Gretel

    2014-01-01

    Introduction: A research article derived from the project entitled “Third Molar Agenesis in Patients at the Orthodontia Postgraduate Clinics at the Universidad Antonio Nariño” carried out in 2011 by the Oral Health Research Group at that same university. Some authors believe that third molar agenesis may be evidence of evolutionary trends, showing a decrease in the size of the jaws and the number of teeth, but in some studies this has been questioned. The objective of this research was to det...

  18. [Osteoradionecrosis of the jaws. Apropos of 7 cases].

    Science.gov (United States)

    Benjelloun, A; Boulaich, M; Alaoui Rachidi, F; Essakalli, L; Benchaqroun, L; Jazouli, N; Lazrak, A; Kzadri, M

    1998-11-01

    Jaw osteoradionecrosis (ORN) is one of the most serious complications of cervico-facial cancer irradiation. Severity is related to major bone lysis and the difficult medical and surgical treatment. We report our experience in seven cases over a ten-year period. Mandibular localization was predominant (85%). The mean age of the patients was 36 years. The average delay to development of ORN was 5.5 years. The treatment was medico-surgical, based on wide surgical exeresis (6/7), frequently via endobuccal surgical approach (4/7). Prevention remains the best treatment of ORN associated with an accurate management of all patients who need radiotherapy.

  19. Multiple fibromyxomas of the jaws: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Zayet, Mohamed Khalifa; Eiid, Salma Belal [Dept. of Oral Radiology, Faculty of Oral and Dental Medicine, Cairo University, Cairo (Egypt)

    2014-09-15

    Fibromyxoma of the jaw is a rare benign mesenchymal odontogenic tumor with locally aggressive behavior. In the present report, a 13-year-old female patient presented to our university hospital with delayed eruption of some of her teeth. A panoramic radiograph taken at the initial examination revealed four pericoronal radiolucencies related to the four third molars. Thereafter, a magnetic resonance imaging (MRI) examination was performed. After the surgical removal of these molars, the microscopic examination diagnosed the four lesions as fibromyxomas. Here, we have discussed the clinical, panoramic radiography, MRI, and histopathological findings of the case.

  20. Applications of Doppler radar to aviation operations - JAWS experiences

    Science.gov (United States)

    Mccarthy, J.; Wilson, J. W.

    1983-01-01

    The field phase of the Joint Airport Weather Studies (JAWS) Project was conducted in the vicinity of Denver's Stapleton International Airport from 15 May to 13 August 1982. The primary collection systems were three Doppler radars, a 27-station, closely spaced (4 km) network of surface stations, and five research aircraft. The program was specifically planned to observe wind shear phenomena with high time and space resolution that would be dangerous to aircraft operations. The program was successful in observing a large number of such events. Preliminary conclusions are presented on the effectiveness of several wind shear detection systems to warn of wind shear events critical to aviation safety.

  1. [Bone tissue morphological structure in congenital deformations of the jaws].

    Science.gov (United States)

    Shishkanov, A V; Panin, M G; Shipkova, T P; Chumakov, A A; Komnova, Z D

    2001-01-01

    Morphological structure of bone tissue was studied in various types of congenital deformations of the jaws. Morphological changes in the bone with deformations and the severity of these disorders depended not so much on the type on the deformation, but mainly on its severity, which can be explained by a drastic increase of functional exercise because of impaired occlusion and impossibility of proper chewing. Decelerated weak restructuring of bone tissue and imperfect osteogenesis in deformed bone, similar in various types of deformations, were demonstrated on morphological material. These changes can affect the regenerative potential of the bone in operated zones.

  2. An ancient gene network is co-opted for teeth on old and new jaws.

    Directory of Open Access Journals (Sweden)

    Gareth J Fraser

    2009-02-01

    Full Text Available Vertebrate dentitions originated in the posterior pharynx of jawless fishes more than half a billion years ago. As gnathostomes (jawed vertebrates evolved, teeth developed on oral jaws and helped to establish the dominance of this lineage on land and in the sea. The advent of oral jaws was facilitated, in part, by absence of hox gene expression in the first, most anterior, pharyngeal arch. Much later in evolutionary time, teleost fishes evolved a novel toothed jaw in the pharynx, the location of the first vertebrate teeth. To examine the evolutionary modularity of dentitions, we asked whether oral and pharyngeal teeth develop using common or independent gene regulatory pathways. First, we showed that tooth number is correlated on oral and pharyngeal jaws across species of cichlid fishes from Lake Malawi (East Africa, suggestive of common regulatory mechanisms for tooth initiation. Surprisingly, we found that cichlid pharyngeal dentitions develop in a region of dense hox gene expression. Thus, regulation of tooth number is conserved, despite distinct developmental environments of oral and pharyngeal jaws; pharyngeal jaws occupy hox-positive, endodermal sites, and oral jaws develop in hox-negative regions with ectodermal cell contributions. Next, we studied the expression of a dental gene network for tooth initiation, most genes of which are similarly deployed across the two disparate jaw sites. This collection of genes includes members of the ectodysplasin pathway, eda and edar, expressed identically during the patterning of oral and pharyngeal teeth. Taken together, these data suggest that pharyngeal teeth of jawless vertebrates utilized an ancient gene network before the origin of oral jaws, oral teeth, and ectodermal appendages. The first vertebrate dentition likely appeared in a hox-positive, endodermal environment and expressed a genetic program including ectodysplasin pathway genes. This ancient regulatory circuit was co-opted and modified

  3. SU-F-E-19: A Novel Method for TrueBeam Jaw Calibration

    Energy Technology Data Exchange (ETDEWEB)

    Corns, R; Zhao, Y; Huang, V [Fraser Valley Cancer Centre - BC Cancer Agency, Surrey, BC (United Kingdom)

    2016-06-15

    Purpose: A simple jaw calibration method is proposed for Varian TrueBeam using an EPID-Encoder combination that gives accurate fields sizes and a homogeneous junction dose. This benefits clinical applications such as mono-isocentric half-beam block breast cancer or head and neck cancer treatment with junction/field matching. Methods: We use EPID imager with pixel size 0.392 mm × 0.392 mm to determine the radiation jaw position as measured from radio-opaque markers aligned with the crosshair. We acquire two images with different symmetric field sizes and record each individual jaw encoder values. A linear relationship between each jaw’s position and its encoder value is established, from which we predict the encoder values that produce the jaw positions required by TrueBeam’s calibration procedure. During TrueBeam’s jaw calibration procedure, we move the jaw with the pendant to set the jaw into position using the predicted encoder value. The overall accuracy is under 0.1 mm. Results: Our in-house software analyses images and provides sub-pixel accuracy to determine field centre and radiation edges (50% dose of the profile). We verified the TrueBeam encoder provides a reliable linear relationship for each individual jaw position (R{sup 2}>0.9999) from which the encoder values necessary to set jaw calibration points (1 cm and 19 cm) are predicted. Junction matching dose inhomogeneities were improved from >±20% to <±6% using this new calibration protocol. However, one technical challenge exists for junction matching, if the collimator walkout is large. Conclusion: Our new TrueBeam jaw calibration method can systematically calibrate the jaws to crosshair within sub-pixel accuracy and provides both good junction doses and field sizes. This method does not compensate for a larger collimator walkout, but can be used as the underlying foundation for addressing the walkout issue.

  4. Static jaw collimation settings to minimize radiation dose to normal brain tissue during stereotactic radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Han, Eun Young, E-mail: eyhan@uams.edu [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR (United States); Zhang Xin; Yan Yulong; Sharma, Sunil; Penagaricano, Jose [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR (United States); Moros, Eduardo [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL (United States); Corry, Peter [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR (United States)

    2012-01-01

    At University of Arkansas for Medical Sciences (UAMS) intracranial stereotactic radiosurgery (SRS) is performed by using a linear accelerator with an add-on micromultileaf collimator (mMLC). In our clinical setting, static jaws are automatically adapted to the furthest edge of the mMLC-defined segments with 2-mm (X jaw) and 5-mm (Y jaw) margin and the same jaw values are applied for all beam angles in the treatment planning system. This additional field gap between the static jaws and the mMLC allows additional radiation dose to normal brain tissue. Because a radiosurgery procedure consists of a single high dose to the planning target volume (PTV), reduction of unnecessary dose to normal brain tissue near the PTV is important, particularly for pediatric patients whose brains are still developing or when a critical organ, such as the optic chiasm, is near the PTV. The purpose of this study was to minimize dose to normal brain tissue by allowing minimal static jaw margin around the mMLC-defined fields and different static jaw values for each beam angle or arc. Dose output factors were measured with various static jaw margins and the results were compared with calculated doses in the treatment planning system. Ten patient plans were randomly selected and recalculated with zero static jaw margins without changing other parameters. Changes of PTV coverage, mean dose to predefined normal brain tissue volume adjacent to PTV, and monitor units were compared. It was found that the dose output percentage difference varied from 4.9-1.3% for the maximum static jaw opening vs. static jaw with zero margins. The mean dose to normal brain tissue at risk adjacent to the PTV was reduced by an average of 1.9%, with negligible PTV coverage loss. This dose reduction strategy may be meaningful in terms of late effects of radiation, particularly in pediatric patients. This study generated clinical knowledge and tools to consistently minimize dose to normal brain tissue.

  5. Longitudinal evaluation of jaw muscle activity and mandibular kinematics in young patients with Class II malocclusion treated with the Teuscher activator.

    Science.gov (United States)

    Cuevas, Maria-José; Cacho, Alberto; Alarcón, Jose-Antonio; Martín, Conchita

    2013-05-01

    A longitudinal study was performed to evaluate the jaw muscle activity and mandibular kinematics after Teuscher activator treatment and at 2 years after orthodontic treatment completion. Twenty-seven children with Class II division 1 malocclusion were evaluated before treatment (T0; mean: 11.6 years), after functional treatment (T1; mean: 12.8 years), and 2 years after orthodontic treatment (T2; mean: 18 years). Bilateral surface electromyographic activities of the anterior temporalis, posterior temporalis, masseter, and suprahyoid muscle areas were analyzed at rest and during clenching, swallowing, and mastication. Kinematic recordings of the mandibular maximum opening, lateral shift, right and left lateral excursions, and protrusion were evaluated. Compared to T0, the left masseter activity during clenching was decreased at T1 but increased at T2, similar to the other evaluated muscles. The suprahyoid activity during swallowing was increased at T1 but decreased at T2. The masseter activity during mastication was increased at T1 and further increased at T2. The left and right lateral excursions and protrusion did not show significant changes throughout the experiment. Teuscher activator and subsequent fixed orthodontic treatment improved jaw muscle function; however, a long period was needed to attain complete neuromuscular adaptation.

  6. [Analysis of clinical outcomes of simplified treatment of lumbar spondylolisthesis with adjacent segment degeneration by MAST Quadrant].

    Science.gov (United States)

    Tang, Jian-Hua; Zhao, Li-Li; Huang, Chun-Ming; Zhong, Cheng-Fan; Li, Xiao-Chuan; He, Yu-Sheng

    2017-09-25

    To explore the method and clinical effect of MAST Quadrant for lumbar spondylolisthesis with adjacent segment degeneration. From April 2014 to January 2016, 36 cases of lumbar spondylolisthesis with adjacent segment degeneration were treated by MAST Quadrant(target nerve decompression and transforaminal lumbar interbody fusion or articulationes zygapophysiales fusion by unilateral fixation with MAST Quadrant). Twenty-three cases were degenerative lumbar spondylolisthesis and 13 cases were isthmic lumbar spondylolisthesis. According to Meyerding grade of spondylolisthesis, 16 cases were grade I, 17 cases were grade II, and 3 cases were grade III. Visual analogue score (VAS), Oswesty Disability Index (ODI) and JOA score were used to evaluate the clinical outcome. The amount of intraoperative bleeding was 230 to 480 ml with an average of 340 ml and the amount of postoperative blood loss was 15 to 80 ml with an average of 43 ml. Operative time was 176 to 240 min with an average of 193 min; X-ray exposure time was 2 to 6 s with an average of 3.6 s. Two cases were complicated with dural tear without nerve injury during operation. Thirty cases were followed up from 12 to 17 months with an average of 15.2 months. VAS scores for preoperative, 5 days, 3 months after surgery were 7.6±1.7, 1.9±0.4, 0.8±0.4 respectively, and there was significant difference before and after operation( P <0.05). The ODI scores for preoperative and 3 months after surgery were 35.9±1.2 and 3.7±0.7 respectively, and there was significant difference before and after operation( P <0.05). JOA scores for preoperative, 5 days, 1 months, 3 months after surgery were 13.2±0.4, 24.4±0.4, 27.4±0.1, 27.9±0.5 respectively, and there was significant difference before and after operation( P <0.05). MAST Quadrant can be applied to treat lumbar spondylolisthesis with adjacent segment degeneration, and the minimally invasive sugical technique is a safe and effective method, with the advantage of simple

  7. The number of zero solutions for complex canonical differential equation of second order with constant coefficients in the first quadrant

    Directory of Open Access Journals (Sweden)

    Vujaković Jelena

    2016-01-01

    Full Text Available The study of complex differential equations in recent years has opened up some of questions concerning the determination of the frequency of zero solutions, the distribution of zero, oscillation of the solution, asymptotic behavior, rank growth and so on. Besides, this is solved by only some classes of differential equations. In this paper, our aim was to determine the number of zeros and their arrangement in the first quadrant, for the complex canonical differential equation of the second order. The accuracy of our results, we illustrate with two examples.

  8. [A case of bisphosphonate-associated osteonecrosis of the jaw in a patient with bone metastasis of breast cancer].

    Science.gov (United States)

    Iimura, Yasuaki; Kaneko, Hiroyuki; Hasegawa, Naoto; Takahashi, Yasuhiro; Shoji, Yasuhito; Kawabata, Makoto

    2010-09-01

    A 5 6-year-old woman underwent modified radical mastectomy for left breast cancer in 2002. Bone metastases developed in November 2005, and she received pamidronate from February 2006. Pamidronate was changed to zoledronate in November 2006. In November 2007, she was referred to a dentist for pain and swelling of the right lower gum. Conservative therapy with local irrigation and antibiotics was performed, but the lesion progressed and showed ulceration with exposed bone. She was diagnosed as bisphosphonate-associated osteonecrosis of the jaws, and zoledronate was withdrawn in January 2008. Conservative therapy was continued but the necrotic lesion caused pathological fracture and fistula. In February 2009, surgical intervention was performed for the improvement of her QOL.

  9. Role of periodontal disease in bisphosphonate-related osteonecrosis of the jaws in ovariectomized rats.

    Science.gov (United States)

    Li, Chun Lei; Lu, Weijia William; Seneviratne, Chaminda Jayampath; Leung, Wai Keung; Zwahlen, Roger A; Zheng, Li Wu

    2016-01-01

    This study aimed to investigate the role of progressive periodontal disease in inducing bisphosphonate-related osteonecrosis of the jaws (BRONJ) using an ovariectomized (OVX) rat model mimicking human intracortical remodeling process. Thirty 12-week-old Spraque-Dawly (SD) female rats were randomly assigned into two groups. All rats underwent bilateral ovariectomy. Six weeks after surgery, zoledronic acid (ZA) or vehicle control was administered intraperitoneally for 12 weeks. On the same day of injection, a cotton ligature was placed subgingivally around the first left lower molar to induce periodontitis. All animals were sacrificed 12 weeks after injection. The entire mandibles were harvested for micro-computed tomography (micro-CT) and histological examinations. Micro-CT examination showed that ligature placement caused significant alveolar bone loss both in ZA (0.63 ± 0.13 vs. 0.38 ± 0.06 mm, P periodontal disease, which might benefit the management of periodontitis, but increase the risk of developing BRONJ. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Jaw cysts - filling or no filling after enucleation? A review.

    Science.gov (United States)

    Ettl, Tobias; Gosau, Martin; Sader, Robert; Reichert, Torsten E

    2012-09-01

    Jaw cysts are common lesions in the oral and maxillofacial region. Enucleation of the lesions and primary closure of the defects, the so-called "cystectomy", has evolved as the treatment of choice. In order to reduce infections and to accelerate bone regeneration, different types of bone grafts are increasingly investigated for defect filling. The present review reflects the most recent studies using autogenous, allogenic, xenogenic and alloplastic bone grafts and compares the results to current investigations about conservative cyst enucleation without using any filling materials. Relevant studies with significant patient sample sizes were electronically searched in PubMed and Medline. Simple cyst enucleation and blood clot healing show low complication rates and sufficient bone regeneration even in large defects. Prospective randomized trials comparing the additional use of filling materials to the "cystectomy" are rare. Currently available data do not indicate the superiority of additional bone grafts. Enucleation of jaw cysts and primary closure without bone substitutes remains "state of the art" in most cases. Copyright © 2011 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  11. Medication-Related Osteonecrosis of the Jaws (MRONJ: Etiological Update

    Directory of Open Access Journals (Sweden)

    Gianluca Tenore

    2014-12-01

    Full Text Available Osteonecrosis of the jaws (ONJ is an uncommon but severe bone disease, can be related to various medicaments (MRONJ including bisphosphonates (BRONJ, antiangiogenic and antiresorptive medicaments such as Denosumab (DRONJ, human monoclonal antibody to the receptor activator of nuclear factor-kB ligand. The rise in number in the latest years can be explained with many patients treated with all these drugs, assumed for osteometabolic (i.e osteoporosis, osteogenesis imperfecta or neoplastic diseases (multiple myeloma, metastatic breast, prostate and renal cancer. The onset mechanism of MRONJ is not entirely understood, probably different mechanisms are involved, such as inhibition of the osteoclasts differentiation and function, decrease of the angiogenesis and inflammation/infection of the jaw bones. Some pathogenetic mechanisms are different according to the drugs, for example the cases of the RANK-ligand inhibitor related ONJ may occur without considering the period of medication intake; also the risk of ONJ manifestation after bisphosphonates (BF is not significantly diminished after interrupting the drug therapy, because BF bind to the bone matrix for many years. Drugs currently implicated in osteonecrosis pathology are various, therefore the term ONJ was currently replaced by MRONJ; it is necessary that the anamnestic phase and management of the patients to be more detailed and correct, not only to prevent osteonecrosis but also to plan all necessary treatments before start of the drug therapy.

  12. A study on the mixed jaw lesions associated with teeth

    International Nuclear Information System (INIS)

    Nah, Kyung Soo

    2000-01-01

    1. Retrospectively evaluate the accuracy of tentative diagnosis or impression from the clinico-radiographic materials of jaw lesions which showed mixed lesions associated with teeth. 2. To observe the diagnostic importance of the calcified part of the lesions which appear as radiopaque areas. 14 cases of jaw lesions which showed mixed lesions associated with teeth were reviewed. These lesions were mostly diagnosed as adenomatoid odontogenic tumors (6 cases) or calcifying odontogenic cysts with (4 cases) or without odontomas (4 cases). The calcified elements of the lesions which demonstrated various sizes and patterns of radiopaque shadows resembled odontoid tissues in some cases but could not be defined in some other cases radiographically. The final histopathologic diagnosis confirmed adenomatoid odontogenic tumors in 4 of the 6 cases. The remaining 2 cases turned out to be odontoma and ameloblastic fibroodontoma. The 4 cases of calcifying odontogenic cysts with odontomas were correct in 3 cases but remaining 1 case was just odontoma. The 4 cases of calcifying odontogenic cysts were proved to be odontogenic keratocyst, calcified peripheral fibroma, unicystic ameloblastoma and squamous cell carcinoma. The diagnostic accuracy of the adenomatoid odontogenic tumors and calcifying odontogenic cysts were high when the lesions show typical appearance. The calcifications which show radiopaque areas could be odontomas or dystrophic calficifations or remnants of bone fragments from resorption.

  13. Aneurysmal bone cysts of the jaws: analysis of 17 cases.

    Science.gov (United States)

    Sun, Zhi-Jun; Zhao, Yi-Fang; Yang, Rui-Li; Zwahlen, Roger A

    2010-09-01

    Aneurysmal bone cysts (ABCs) are benign osteolytic lesions that occur relatively rarely in the jaws. The aim of the present study was to investigate the clinical and radiographic characteristics, pathologic features, and treatment results of ABCs of the jaws (JABCs). A retrospective analysis of a 20-year database, including 17 cases of JABC, was performed. A total of 17 patients, 9 males and 8 females, aged 7 to 47 years (mean 20.4, median 14), were included. Of the 17 lesions, 15 (88.2%) were located in the mandible and 2 (11.8%) in the maxilla. A painless (12 of 17, 70.6%) or painful (3 of 17, 17.6%) swelling was the most common clinical finding. The pathologic analyses revealed that 13 JABCs (76.5%) were secondary in nature, including 11 cases associated with ossifying fibroma. Radiologically, the lesions frequently presented as multilocular (58.8%), well-defined (70.6%) radiolucencies (82.4%). Two lesions (11.8%) recurred. Our results suggest that most JABCs are secondary in nature and frequently associated with ossifying fibroma. The patients with JABCs presented with various clinical and radiographic features and therefore often posed a diagnostic dilemma. Resection is the preferred treatment of JABCs. Copyright 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  14. A study on the mixed jaw lesions associated with teeth

    Energy Technology Data Exchange (ETDEWEB)

    Nah, Kyung Soo [Dept. of Dental Radiology, College of Dentistry, Pusan National University, Pusan (Korea, Republic of)

    2000-03-15

    1. Retrospectively evaluate the accuracy of tentative diagnosis or impression from the clinico-radiographic materials of jaw lesions which showed mixed lesions associated with teeth. 2. To observe the diagnostic importance of the calcified part of the lesions which appear as radiopaque areas. 14 cases of jaw lesions which showed mixed lesions associated with teeth were reviewed. These lesions were mostly diagnosed as adenomatoid odontogenic tumors (6 cases) or calcifying odontogenic cysts with (4 cases) or without odontomas (4 cases). The calcified elements of the lesions which demonstrated various sizes and patterns of radiopaque shadows resembled odontoid tissues in some cases but could not be defined in some other cases radiographically. The final histopathologic diagnosis confirmed adenomatoid odontogenic tumors in 4 of the 6 cases. The remaining 2 cases turned out to be odontoma and ameloblastic fibroodontoma. The 4 cases of calcifying odontogenic cysts with odontomas were correct in 3 cases but remaining 1 case was just odontoma. The 4 cases of calcifying odontogenic cysts were proved to be odontogenic keratocyst, calcified peripheral fibroma, unicystic ameloblastoma and squamous cell carcinoma. The diagnostic accuracy of the adenomatoid odontogenic tumors and calcifying odontogenic cysts were high when the lesions show typical appearance. The calcifications which show radiopaque areas could be odontomas or dystrophic calficifations or remnants of bone fragments from resorption.

  15. DENOSUMAB-RELATED OSTEONECROSIS OF THE JAWS: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Milena Petkova

    2017-03-01

    Full Text Available Bisphosphonates are potent and effective drugs frequently used to prevent the skeletal complications associated with postmenopausal osteoporosis in women, to manage patients with multiple myeloma, hypercalcemia, and metastasis of cancer to the bone. The search for new medications with the same therapeutic effectiveness as the bisphosphonates but fewer side effects has resulted in the discovery of Denosumab, a human monoclonal antibody against the receptor activator for nuclear factor kappa B ligand (RANKL, therefore inhibiting osteoclast differentiation and function. Denosumab is a class of drugs that are entirely different from the traditional antiresorptive drugs, the bisphosphonates. Denosumab has several advantages, including better tolerability, ease of subcutaneous injection, a shorter half-life, and a reduced incidence of nephrotoxicity. Patients receiving bisphosphonates are at risk to develop a severe devastating complication - osteonecrosis of the jaws (ONJ - which is challenging to treat. Since 2010 there have been reports of ONJ in patients taking denosumab. In the 2014 position paper of the American Association of Oral and Maxillofacial Surgeons, the nomenclature “bisphosphonate-related osteonecrosis of the jaw” was changed to “medication related osteonecrosis of the jaw” (MRONJ. The change is justified to accommodate the growing number of osteonecrosis cases involving the maxilla and mandible associated with other antiresorptive (denosumab and antiangiogenic therapies. Here we report a development of denosumab-related osteonecrosis of the jaw (DRONJ - a new type of bony necrosis- in patient with bone metastases of breast cancer on Denosumab therapy. The patient has no previous history of taking bisphosphonates.

  16. Microbiota associated with chronic osteomyelitis of the jaws

    Directory of Open Access Journals (Sweden)

    Elerson Gaetti-Jardim Júnior

    2010-12-01

    Full Text Available Chronic osteomyelitis of maxilla and mandible is rare in industrialized countries and its occurrence in developing countries is associated with trauma and surgery, and its microbial etiology has not been studied thoroughly. The aim of this investigation was to evaluate the microbiota associated with osteomyelitis of mandible or maxilla from some Brazilian patients. After clinical and radiographic evaluation, samples of bone sequestra, purulent secretion, and biopsies of granulomatous tissues from twenty-two patients with chronic osteomyelitis of mandible and maxilla were cultivated and submitted for pathogen detection by using a PCR method. Each patient harbored a single lesion. Bacterial isolation was performed on fastidious anaerobe agar supplemented with hemin, menadione and horse blood for anaerobes; and on tryptic soy agar supplemented with yeast extract and horse blood for facultative bacteria and aerobes. Plates were incubated in anaerobiosis and aerobiosis, at 37ºC for 14 and 3 days, respectively. Bacteria were cultivated from twelve patient samples; and genera Actinomyces, Fusobacterium, Parvimonas, and Staphylococcus were the most frequent. By PCR, bacterial DNA was detected from sixteen patient samples. The results suggest that cases of chronic osteomyelitis of the jaws are usually mixed anaerobic infections, reinforcing the concept that osteomyelitis of the jaws are mainly related to microorganisms from the oral environment, and periapical and periodontal infections may act as predisposing factors.

  17. Jaw Musculature of the Picini (Aves: Piciformes: Picidae

    Directory of Open Access Journals (Sweden)

    Reginaldo José Donatelli

    2012-01-01

    Full Text Available The Picini tribe comprises 25 Old World woodpecker species grouped into seven genera that are widely distributed in Asia and include several representatives from the Eurasian region. Given the absence of detailed anatomical studies of Picini in the literature, the purposes of this study were to describe the jaw musculature of 14 species of Picini in detail and to compare the musculature patterns of these species. The results of this analysis indicate the following: (1 there is a clear association between the ventralis lateralis and dorsalis lateralis muscles through fleshy fibers that are connected in all species, (2 the jaw musculature of the genus Picus differs from that of other Picini genera in terms of the poor development of the protractor muscle system of the quadrate (M. protractor quadrati and M. protractor pterygoidei, (3 generally, the M. pseudotemporalis superficialis originates in the ventrocaudal region of the laterosphenoid (the lower part of the orbit, with the only noteworthy exception being an origin in the upper part of the orbit in Dinopium javanense, and (4 the protractor pterygoidei muscle is more developed in Blythipicus rubiginosus, Dinopium rafflesii, and D. javanense than in the other species.

  18. Analysis of the Single Toggle Jaw Crusher Force Transmission Characteristics

    Directory of Open Access Journals (Sweden)

    Moses Frank Oduori

    2016-01-01

    Full Text Available This paper sets out to perform a static force analysis of the single toggle jaw crusher mechanism and to obtain the force transmission characteristics of the mechanism. In order to obtain force transmission metrics that are characteristic of the structure of the mechanism, such influences as friction, dead weight, and inertia are considered to be extraneous and neglected. Equations are obtained by considering the balance of forces at the moving joints and appropriately relating these to the input torque and the output torque. A mechanical advantage, the corresponding transmitted torque, and the variations thereof, during the cycle of motion of the mechanism, are obtained. The mechanical advantage that characterizes the mechanism is calculated as the mean value over the active crushing stroke of the mechanism. The force transmission characteristics can be used as criteria for the comparison of different jaw crusher mechanism designs in order to select the most suitable design for a given application. The equations obtained can also be used in estimating the forces sustained by the components of the mechanism.

  19. Convergent evolution of hemoglobin switching in jawed and jawless vertebrates.

    Science.gov (United States)

    Rohlfing, Kim; Stuhlmann, Friederike; Docker, Margaret F; Burmester, Thorsten

    2016-02-01

    During development, humans and other jawed vertebrates (Gnathostomata) express distinct hemoglobin genes, resulting in different hemoglobin tetramers. Embryonic and fetal hemoglobin have higher oxygen affinities than the adult hemoglobin, sustaining the oxygen demand of the developing organism. Little is known about the expression of hemoglobins during development of jawless vertebrates (Agnatha). We identified three hemoglobin switches in the life cycle of the sea lamprey. Three hemoglobin genes are specifically expressed in the embryo, four genes in the filter feeding larva (ammocoete), and nine genes correspond to the adult hemoglobin chains. During the development from the parasitic to the reproductive adult, the composition of hemoglobin changes again, with a massive increase of chain aHb1. A single hemoglobin chain is expressed constitutively in all stages. We further showed the differential expression of other globin genes: Myoglobin 1 is most highly expressed in the reproductive adult, myoglobin 2 expression peaks in the larva. Globin X1 is restricted to the embryo; globin X2 was only found in the reproductive adult. Cytoglobin is expressed at low levels throughout the life cycle. Because the hemoglobins of jawed and jawless vertebrates evolved independently from a common globin ancestor, hemoglobin switching must also have evolved convergently in these taxa. Notably, the ontogeny of sea lamprey hemoglobins essentially recapitulates their phylogeny, with the embryonic hemoglobins emerging first, followed by the evolution of larval and adult hemoglobins.

  20. Epidemiology of ameloblastomas of the jaws; a report from the Netherlands

    NARCIS (Netherlands)

    Oomens, M.A.E.M.; van der Waal, I.

    2014-01-01

    Objectives: To provide epidemiological data of ameloblastomas of the jaws in the Netherlands over a 25-year time period (1985-2010) and to compare these data with data from other parts of the world. Material and Methods: The data of all patients diagnosed with a primary ameloblastoma of the jaws in

  1. Differences in loading of the temporomandibular joint during opening and closing of the jaw

    NARCIS (Netherlands)

    Tuijt, M.; Koolstra, J.H.; Lobbezoo, F.; Naeije, M.

    2010-01-01

    Kinematics of the human masticatory system during opening and closing of the jaw have been reported widely. Evidence has been provided that the opening and closing movement of the jaw differ from one another. However, different approaches of movement registration yield divergent expectations with

  2. Provocation of delayed-onset muscle soreness in the human jaw-closing muscles

    NARCIS (Netherlands)

    Türker, K.S.; Koutris, M.; Sümer, N.C.; Atis, E.S.; Linke, I.R.; Lobbezoo, F.; Naeije, M.

    2010-01-01

    Eccentric contractions of jaw-closing muscles are difficult to perform. This may explain why fatigue-inducing experiments performed so far suggest the jaw-closing muscles to be fatigue resistant. Aim of this study was to construct an apparatus that can impose intense eccentric contractions to the

  3. Osteonecrosis of the jaw-a bone site - specific effect of bisphosphonates

    NARCIS (Netherlands)

    Vermeer, J.A.F.; Renders, G.A.P.; Everts, V.

    2016-01-01

    A known complication that can occur in patients using bisphosphonates (BPs) is osteonecrosis of the jaw (ONJ). ONJ features bone exposure that may be associated with severe pain, swelling, local infection, and pathological fracture of the jaw. Current literature indicates that a complex combination

  4. Comparison of nonexposed and exposed bisphosphonate-induced osteonecrosis of the jaws

    DEFF Research Database (Denmark)

    Schiodt, Morten; Reibel, Jesper; Oturai, Peter

    2014-01-01

    Nonexposed osteonecrosis of the jaws (NE-ONJ) does not fit into the current definition of osteonecrosis, which requires exposed bone. A modification of the classification of bisphosphonate-induced osteonecrosis of the jaws (ONJ) is proposed. This study aimed to test proposed criteria for NE...

  5. Temporomandibular pain and jaw dysfunction at different ages covering the lifespan - A population based study

    NARCIS (Netherlands)

    Lovgren, A.; Haggman-Henrikson, B.; Visscher, C.M.; Lobbezoo, F.; Marklund, S.; Wanman, A.

    2016-01-01

    Background: Temporomandibular pain and jaw dysfunction can have a negative effect on daily life, but these conditions are not well recognized in the health care systems. The general aim was to examine the cross-sectional prevalence of frequent temporomandibular pain and jaw dysfunction in men and

  6. Changes in rabbit jaw-muscle activity parameters in response to reduced masticatory load

    NARCIS (Netherlands)

    Grünheid, T.; Brugman, P.; Zentner, A.; Langenbach, G.E.J.

    2010-01-01

    Mechanical food properties influence the neuromuscular activity of jaw-closing muscles during mastication. It is, however, unknown how the activity profiles of the jaw muscles are influenced by long-term alterations in masticatory load. In order to elucidate the effect of reduced masticatory load on

  7. Left atrial volume index

    DEFF Research Database (Denmark)

    Poulsen, Mikael K; Dahl, Jordi S; Henriksen, Jan Erik

    2013-01-01

    To determine the prognostic importance of left atrial (LA) dilatation in patients with type 2 diabetes (T2DM) and no history of cardiovascular disease.......To determine the prognostic importance of left atrial (LA) dilatation in patients with type 2 diabetes (T2DM) and no history of cardiovascular disease....

  8. Development of 4D jaw movement visualization system for dental diagnosis support

    Science.gov (United States)

    Aoki, Yoshimitsu; Terajima, Masahiko; Nakasima, Akihiko

    2004-10-01

    A person with an asymmetric morphology of maxillofacial skeleton reportedly possesses an asymmetric jaw function and the risk to express temporomandibular disorder is high. A comprehensive analysis from the point of view of both the morphology and the function such as maxillofacial or temporomandibular joint morphology, dental occlusion, and features of mandibular movement pathways is essential. In this study, the 4D jaw movement visualization system was developed to visually understand the characteristic jaw movement, 3D maxillofacial skeleton structure, and the alignment of the upper and lower teeth of a patient. For this purpose, the 3D reconstructed images of the cranial and mandibular bones, obtained by computed tomography, were measured using a non-contact 3D measuring device, and the obtained morphological images of teeth model were integrated and activated on the 6 DOF jaw movement data. This system was experimentally applied and visualized in a jaw deformity patient and its usability as a clinical diagnostic support system was verified.

  9. Mouse preferential incising force orientation changes during jaw closing muscle hyperalgesia and is sex dependent.

    Science.gov (United States)

    Widmer, C G; Morris-Wiman, J

    2016-12-01

    Mouse incising is controlled by a central pattern generator and this activity can change in the presence of pain. The incising frequency and maximum force generation decreases with pain. In this study, we used repetitive acidic injections in the left masseter muscle of male and female mice to determine differences between baseline and jaw muscle pain conditions and the effect of sex on preferential incising direction. A within subject design was used to evaluate data previously acquired using multi-axis force data (X, Y and Z) from the 4th baseline recording day and day 7 post-injection (day of maximal pain response) for each mouse of each sex. A total of 34 female and male (age 3-9months) CD-1 mice were evaluated. After mathematically rotating the X and Y axes to align the Y axis to be parallel to the wire struts of the cage top, data were analyzed to determine incising direction preference during baseline (non-pain) and pain (day 7) conditions and between sex. Radar plots of X-Y, X-Z and Y-Z axes depicted the average direction of incising preference between baseline and pain conditions for each sex. Statistical differences among groups were tested using a mixed model ANOVA. Similar to previous findings, female mice had a more robust difference in incising direction preference when comparing male and female pain conditions and this was most evident in the X-Z axes. The incising frequencies most commonly affected were 5.3, 6.2 and 7.6Hz. Male mice varied little in their incising direction preference between the baseline and pain conditions. In addition, statistical comparison of ratios of the percent of time spent incising in the Z versus X axes for each incising frequency found that the incising preference was not different when comparing 5.3 and 7.6Hz frequencies. Finally, female mice used a novel approach to minimize pain while incising by rotating their head and body nearly 180 degrees while males did not use this strategy as frequently. The preferred incising

  10. [Osteonecrosis of the jaws by long term therapy with bisphosphonates].

    Science.gov (United States)

    Piesold, Jörn-Uwe; Al-Nawas, Bilal; Grötz, Knut A

    2006-09-01

    For several decades bisphosphonates have been used to reduce skeletal related events in patients with both osteoporosis or bone metastases. Under long term application, besides the known therapy side effects, a new clinical picture has been described within the last few years. This is osteonecrosis of the jaws, which is characterized by its difficulty in treatment. Besides exposed jaw bone, the start of the disease usually lacks any symptoms. The typical clinical symptoms then are foetor ex ore, swelling, exsudation, loosening of teeth, pain or paresthesia. Later oro-antral/nasal or oro-cutaneous fistula can develop. The X-ray shows persisting tooth sockets after extractions and later cloudy radio-lucency, sequestra or fractures. The patient exposed to bisphosphonate can be grouped according to the risk for osteonecrosis: high risk patients with intravenous bisphosphonate therapy and additional chemo-, radiation or corticoid therapy--predominantly patients with a malignant underlying disease and bone metastases low risk patients with an oral bisphosphonate therapy without additional chemo-, radiation or corticoid therapy--preferably patients with non-corticoid-induced osteoporosis. Before starting a bisphosphonate therapy possible causes of infection should be treated and risk of injuries to the mucosa should be reduced according to the individual risk profile. This is supplemented by information of the patient about the risk of necrosis and the possibilities for prevention. Regular dental recall under bisphophonate therapy is emphasised for early recognition of possible problems. Prophylaxis is recommended for the prevention of periodontal infection combined with a follow up of removable denture for possible ulcera. Generally, conservative treatment measures are preferred to surgical ones. Inevitable operations are carried out non-traumatically using broad spectrum antibiotic prophylaxis until the day of suture removal (not before day 10). Long term follow up

  11. Left heart catheterization

    Science.gov (United States)

    Catheterization - left heart ... to help guide the catheters up into your heart and arteries. Dye (sometimes called "contrast") will be ... in the blood vessels that lead to your heart. The catheter is then moved through the aortic ...

  12. Evolution of a unique predatory feeding apparatus: functional anatomy, development and a genetic locus for jaw laterality in Lake Tanganyika scale-eating cichlids

    Directory of Open Access Journals (Sweden)

    Albertson R Craig

    2010-01-01

    Full Text Available Abstract Background While bilaterality is a defining characteristic of triploblastic animals, several assemblages have managed to break this symmetry in order to exploit the adaptive peaks garnered through the lateralization of behaviour or morphology. One striking example of an evolved asymmetry in vertebrates comes from a group of scale-eating cichlid fishes from Lake Tanganyika. Members of the Perissodini tribe of cichlid fishes have evolved dental and craniofacial asymmetries in order to more effectively remove scales from the left or right flanks of prey. Here we examine the evolution and development of craniofacial morphology and laterality among Lake Tanganyika scale-eating cichlids. Results Using both geometric and traditional morphometric methods we found that the craniofacial evolution in the Perissodini involved discrete shifts in skeletal anatomy that reflect differences in habitat preference and predation strategies. Further, we show that the evolutionary history of the Perissodini is characterized by an accentuation of craniofacial laterality such that certain taxa show elaborate sided differences in craniofacial shape consistent with the sub-partitioning of function between sides of the head during attacks. Craniofacial laterality in the scale-eating specialist Perissodus microlepis was found to be evident early in development and exhibited a unimodal distribution, which is contrary to the adult condition where jaw laterality has been described as a discrete, bimodal antisymmetry. Finally, using linkage and association analyses we identified a conserved locus for jaw handedness that segregates among East African cichlids. Conclusions We suggest that, during the evolution of the Perissodini, selection has accentuated a latent, genetically determined handedness of the craniofacial skeleton, enabling the evolution of jaw asymmetries in order to increase predation success. Continued work on the developmental genetic basis of

  13. Fibro-osseous lesions of the face and jaws.

    Science.gov (United States)

    MacDonald-Jankowski, D S

    2004-01-01

    Maxillofacial fibro-osseous lesions (FOL) consists of lesions that differ, with the exception of fibrous dysplasia, to those found in the rest of the skeleton. FOLs of the face and jaws are cemento-osseous [corrected] dysplasia, fibrous dysplasia and cemento-ossifying fibroma. Radiology is central to their diagnosis because the pathology for all FOLs is similar, although they range widely in behaviour, from dysplasia, hamartoma to benign neoplasia with occasional recurrence. Furthermore, once diagnosed the management of each is different. For cemento-ossifying dysplasia, this may mean doing nothing, simply because no treatment is generally appropriate. Almost all cemento-osseous [corrected] fibromas should be treated surgically, whereas cases of fibrous dysplasia are treated according to their clinical presentation, ranging from review and follow-up to surgery necessary to save the patient's sight or reduce deformity. The most important and frequent features of the FOLs differential diagnosis is discussed with assistance of a flow-chart.

  14. Osteosarcomas and chondrosarcomas of the jaws: immunohistochemical correlations.

    Science.gov (United States)

    Regezi, J A; Zarbo, R J; McClatchey, K D; Courtney, R M; Crissman, J D

    1987-09-01

    Clinical, microscopic, and immunohistochemical characteristics of 17 jaw sarcomas are reported. Histologic subtypes included chondroblastic (five), fibroblastic (five), osteoblastic (three), telangiectatic (one), parosteal (two), and chondrosarcoma (one). Reactivity for all antigenic markers in decalcified tissue was judged to be comparable to nondecalcified tissue. All neoplasms were nonreactive for muramidase and leukocyte common antigen. alpha-1 Antichymotrypsin and HLA-DR immunoreactivity was found focally. Positive S-100 staining was found predominantly in chondrocytes. All tumors were positive for vimentin. Cells in focal zones of cartilage were positive for keratin. No distinctive pattern emerged relative to clinical recurrence and histologic subtype or immunotype. Leukocyte common antigen determinations were useful because they distinguished between neoplastic and inflammatory cells. S-100 protein stains helped in the subclassification of chondroblastic osteosarcoma, and vimentin stains confirmed mesenchymal origin. Cross-reactive staining of cartilage with keratin antibodies was regarded as a possible diagnostic pitfall.

  15. Fibro-osseous lesions of the face and jaws

    International Nuclear Information System (INIS)

    MacDonald-Jankowski, D.S.

    2004-01-01

    Maxillofacial fibro-osseous lesions (FOL) consists of lesions that differ, with the exception of fibrous dysplasia, to those found in the rest of the skeleton. FOLs of the face and jaws are cemento-ossifying dysplasia, fibrous dysplasia and cemento-ossifying fibroma. Radiology is central to their diagnosis because the pathology for all FOLs is similar, although they range widely in behaviour, from dysplasia, hamartoma to benign neoplasia with occasional recurrence. Furthermore, once diagnosed the management of each is different. For cemento-ossifying dysplasia, this may mean doing nothing, simply because no treatment is generally appropriate. Almost all cemento-ossifying fibromas should be treated surgically, whereas cases of fibrous dysplasia are treated according to their clinical presentation, ranging from review and follow-up to surgery necessary to save the patient's sight or reduce deformity. The most important and frequent features of the FOLs differential diagnosis is discussed with assistance of a flow-chart

  16. [Central giant cell reparative granuloma of the jaw].

    Science.gov (United States)

    Boulaich, M; Benbouzid, M A; Lazrak, A; Benchaqroun, L; Jazouli, N; Mahassini, N; Saidi, A; Kzadri, M

    1995-01-01

    The authors report a series of 22 cases of central giant cells Granuloma of the jaws. There were 12 located in the maxilla, and 10 in the mandible. The majority of lesions were observed in patients under the age of 30 years, and occurs more often in females than in males, particularly in mandibular lesions. This lesion, which the pathogenesis still remains obscure, appears as radiolucency, well or ill-defined, uni or multilocular with trabeculations coursing through the lesion. Histologic study shows giant cells, fibroblastic cells, and foci of hemorrhage and osteoid tissue. The authors insist on the problem of differential diagnosis which can make a radiolucency with giant cells. It must be differentiated especially from giant cells tumor, which treatment and course are different. Finally, the authors underline a good prognosis of this lesion, which simple curettage is generally sufficient, and which recurrences remain rare.

  17. Fibro-osseous lesions of the face and jaws

    Energy Technology Data Exchange (ETDEWEB)

    MacDonald-Jankowski, D.S

    2004-01-01

    Maxillofacial fibro-osseous lesions (FOL) consists of lesions that differ, with the exception of fibrous dysplasia, to those found in the rest of the skeleton. FOLs of the face and jaws are cemento-ossifying dysplasia, fibrous dysplasia and cemento-ossifying fibroma. Radiology is central to their diagnosis because the pathology for all FOLs is similar, although they range widely in behaviour, from dysplasia, hamartoma to benign neoplasia with occasional recurrence. Furthermore, once diagnosed the management of each is different. For cemento-ossifying dysplasia, this may mean doing nothing, simply because no treatment is generally appropriate. Almost all cemento-ossifying fibromas should be treated surgically, whereas cases of fibrous dysplasia are treated according to their clinical presentation, ranging from review and follow-up to surgery necessary to save the patient's sight or reduce deformity. The most important and frequent features of the FOLs differential diagnosis is discussed with assistance of a flow-chart.

  18. Osteoporosis and bisphosphonate-related osteonecrosis of the jaw bone.

    Science.gov (United States)

    Villa, Alessandro; Castiglioni, Stefano; Peretti, Alessandro; Omodei, Marco; Ferrieri, Giovanni B; Abati, Silvio

    2011-01-01

    The aim of this longitudinal study is to present data from 76 female patients treated with bisphosphonates (BPs) for postmenopausal osteoporosis and referred to the Unit of Oral Diagnosis and Day Surgery of the University of Milano for diagnosis and treatment. All patients received a thorough oral examination. The diagnosis of osteonecrosis of the jaw bone (ONJ) was made from radiographic and clinical findings. 9% of individuals had BRONJ at first visit. Patients with dental or periodontal abscess were significantly more likely to develop BRONJ (OR: 2.9, 95% CI 0.5-15.9). Patients with osteoporosis receiving BPs may develop BRONJ, especially in the presence of an active infectious process in the mouth. Clinicians should carefully follow up on individuals receiving bisphosphonates therapy to avoid the occurrence of osteonecrotic lesions.

  19. Automatic evaluation of task-focused parallel jaw gripper design

    DEFF Research Database (Denmark)

    Wolniakowski, Adam; Miatliuk, Konstantsin; Krüger, Norbert

    2014-01-01

    In this paper, we suggest gripper quality metrics that indicate the performance of a gripper given an object CAD model and a task description. Those, we argue, can be used in the design and selection of an appropriate gripper when the task is known. We present three different gripper metrics that...... that to some degree build on existing grasp quality metrics and demonstrate these on a selection of parallel jaw grippers. We furthermore demonstrate the performance of the metrics in three different industrial task contexts.......In this paper, we suggest gripper quality metrics that indicate the performance of a gripper given an object CAD model and a task description. Those, we argue, can be used in the design and selection of an appropriate gripper when the task is known. We present three different gripper metrics...

  20. Bisphosphonate-related osteonecrosis of the jaws (Bronj).

    Science.gov (United States)

    Beninati, Francesco; Pruneti, Riccardo; Ficarra, Giuseppe

    2013-09-01

    Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is an extremely therapy resistant osteomyelitis-like disease exclusively involving the jaw bones of patients in treatment with bisphosphonates (BPs). The aim of this study was to evaluate the radiological and clinical findings and management of 51 patients with BRONJ diagnosed from 2004 to 2009 in our Reference Center. A prospective study was performed. The patients were examined every 2-6 months, depending on their clinical conditions. Positive outcome variables were the resolution of symptoms, persistence of bone exposure and /or fistula and the status of the lesional mucosa. The higher prevalence of the disease was noted in 2006 and 2007 and at the time of diagnosis 90% of patients had been treated with iv BPs. The main precipitating event leading to BRONJ was an invasive dental procedure in 61% of patients while no traumatic event could be identified in 16% of patients. The median time of follow-up was 19 months (range: 2-57), during which 31% of patients healed and 39% succumbed. In 78% of patients the therapy was medical, in 16% it consisted in surgical deep curettage and only in 6% it was necessary to perform an osteotomy to avoid a mandibular pathological fracture. All the patients in treatment with oral BPs healed from BRONJ with a median time of conservative treatment of 19 months. Prevention has lead to a progressive reduction in the prevalence of BRONJ. In our experience medical treatment is often sufficient to keep the disease under control and to lead to the healing of the lesions by spontaneous loss of the sequestrum. This approach seems to be very effective in patients who were in treatment with oral Bps preparations; BRONJ seems to have a more benign clinical behaviour in these patients.

  1. Jaw expansive lesions: population incidence and CT dentalscan role.

    Science.gov (United States)

    Fiaschetti, V; Fanucci, E; Rascioni, M; Ottria, L; Barlattani, A; Simonetti, G

    2010-07-01

    The aim of the study is to evaluate the incidence of different expansive lesions and the advantages of the clinical employment of Dentalscan to study bones lesions and to establish a common diagnostic path. Since January 2005 to November 2009, 3200 patients, not selected for sex or age, have undergone a CT "Dentalscan" in the department of Diagnostic Imaging, Tor Vergata University Hospital (PTV), a suspect bone pathology was found in 704 of them through the XR-orthopantomograpy (OPT). CT images were obtained with General Electric CT Light Speed multislice. Images were saved in the Advantage Workstation (GE) supported by the "Dentascan" dedicated software and by the 3D software (3D SSD). The protocol was : Slice thickness 1,25 mm, gap 0, matrix 512 × 512, 140 KV and 70 mA. All the lesions were also studied with the dedicated three-dimensional reconstructor 3D SSD. Biopsy for diagnosis was performed on all the lesions, except one (false positive with digital OPT). THE TECHNIQUE SENSITIVITY WAS ASSESSED FOR TWO IMPORTANT CLASSES: benign and malignant lesions. Through CT Dentascan a detailed evaluation of the jaws lesions and their extension was obtained. 656 patients (93.1 %) out of 704 examined for a suspicious lesion on the orthopantomography had a benign lesion: (127 follicular cysts (18.2 %), 181 radicular cysts (25.1%), 93 non odontogenic cysts (13.2%), 29 fibroma (4.2%), 198 odontomes (28.2%), 24 ameloblastoma (3.6%), 4 brown tumors (0.7%), 47 (6.9%) had malignant lesions: (12 carcinoma (1.7%), 29 metastasis (4.3%), 6 sarcoma (0.8%), 1 Dentascan CT resulted to be negative (1 false positive of digital OPT). The sensitivity of the technique for both groups was 99% for benign lesions and 98% for malign lesions. CT Dentascan characteristics suggest to consider these techniques as the gold standard for the evaluation of jaw expansive lesions and the support of surgical planning.

  2. Understanding bisphosphonates and osteonecrosis of the jaw: uses and risks.

    Science.gov (United States)

    Rosini, S; Rosini, S; Bertoldi, I; Frediani, B

    2015-09-01

    Bisphosphonates are chemically stable analogs of pyrophosphate compounds, which have been used to treat multiple disorders of calcium metabolism. Although bisphosphonates have been employed for many years and have demonstrated an excellent safety profile, severe osteonecrosis of the jaw (ONJ) has been described in patients with bone metastases who have been treated with bisphosphonates. In this review we describe the reasons for ONJ and discuss the varying effects of different bisphosphonates on the development of ONJ. Bisphosphonates tend to accumulate in bone, subject to remodeling (such as the jaw) and can affect osteoclast-mediated bone resorption and osteoclast formation, leading to the osteonecrosistic phenomenon. Risk factors for previously -treated patients include the type of bisphosphonates (amino or non-amino), length of treatment and route of administration, the presence of co-morbidities and/or treatment with immune-suppressing drugs, and the presence of other risk factors in addition to the type of intervention required. In oncological patients currently in treatment with receiving intravenous bisphosphonates, greater consideration must be taken depending on the length of treatment already undertaken and concomitant therapies. In these patients, a preventive dental surgery visit and examination of the case would be advisable prior to beginning treatment with bisphosphonates. Practical approaches in the prevention of ONJ include thorough pre-treatment evaluation and performing any preventative procedures (treat periodontal conditions, extract loose teeth, provide protective and endodontic therapies); initiating amino-bisphosphonates only after any gum tissue damage has healed; establishing a regimented check-up schedule and hygieneic precautions the patient can take; and during bisphosphonate treatment conduct any dental procedures in the least invasive manner during bisphosphonate treatment.

  3. Osteonecrosis of the jaws: a review and update in etiology and treatment.

    Science.gov (United States)

    Ribeiro, Guilherme H; Chrun, Emanuely S; Dutra, Kamile L; Daniel, Filipe I; Grando, Liliane J

    2017-06-24

    Osteonecrosis of the jaws can result either from radiation, used in radiotherapy for treatment of malignant tumors, or medications used for bone remodeling and anti-angiogenesis such as bisphosphonates. These conditions can be associated with triggering factors such as infection, trauma and decreased vascularity. The management of patients with osteonecrosis of the jaws requires caution since there is no specific treatment that acts isolated and decidedly. However, different treatment modalities can be employed in an associated manner to control and stabilize lesions. To review the current knowledge on etiology and management of osteonecrosis of the jaws, both radio-induced and medication-related, aiming to improve knowledge of professionals seeking to improve the quality of life of their patients. Literature review in PubMed as well as manual search for relevant publications in reference list of selected articles. Articles in English ranging from 1983 to 2017, which assessed osteonecrosis of the jaws as main objective, were selected and analyzed. Infections, traumas and decreased vascularity have a triggering role for osteonecrosis of the jaws. Prophylactic and/or stabilizing measures can be employed in association with therapeutic modalities to properly manage osteonecrosis of the jaws patients. Selecting an appropriate therapy for osteonecrosis of the jaws management based on current literature is a rational decision that can help lead to a proper treatment plan. Copyright © 2017 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  4. Masticatory jaw movement of Exaeretodon argentinus (Therapsida: Cynodontia inferred from its dental microwear.

    Directory of Open Access Journals (Sweden)

    Tai Kubo

    Full Text Available Dental microwear of four postcanine teeth of Exaeretodon argentinus was analyzed using both two dimensional (2D and three dimensional (3D methods to infer their masticatory jaw movements. Results of both methods were congruent, showing that linear microwear features (scratches were well aligned and mostly directed to the antero-posterior direction in all four teeth examined. These findings support the palinal masticatory jaw movement, which was inferred in previous studies based on the observation of gross morphology of wear facets. In contrast, the lack of detection of lateral scratches confirmed the absence of the lateral jaw movement that was also proposed by a previous study. Considering previous microwear studies on cynodonts, palinal jaw movements observed in Exaeretodon evolved within cynognathian cynodonts from the fully orthal jaw movement of its basal member. Although there are currently only three studies of dental microwear of non-mammalian cynodonts including the present study, microwear analysis is a useful tool for the reconstruction of masticatory jaw movement and its future application to various cynodonts will shed light on the evolutionary process of jaw movement towards the mammalian condition in more detail.

  5. Pain and Disability in the Jaw and Neck Region following Whiplash Trauma.

    Science.gov (United States)

    Häggman-Henrikson, B; Lampa, E; Marklund, S; Wänman, A

    2016-09-01

    The relationship between whiplash trauma and chronic orofacial pain is unclear, especially with regard to the time elapsed from trauma to development of orofacial pain. The aim was to analyze prevalence of jaw pain and disability, as well as the relationship between pain and disability in the jaw and neck regions in the early nonchronic stage after whiplash trauma. In this case-control study, 70 individuals (40 women, 30 men, mean age 35.5 y) who visited an emergency department with neck pain following a car accident were examined within 3 wk of trauma (group 1) and compared with 70 individuals (42 women, 28 men, mean age 33.8 y), who declined to attend a clinical examination but agreed to fill in questionnaires (group 2). The 2 case groups were compared with a matched control group of 70 individuals (42 women, 28 men, mean age 37.6 y) without a history of neck trauma. All participants completed questionnaires regarding jaw pain and dysfunction, rating pain intensity in jaw and neck regions on the Numerical Rating Scale, the Neck Disability Index, and Jaw Disability Checklist. Compared with controls, individuals with a recent whiplash trauma reported more jaw pain and dysfunction. Furthermore, there was a moderate positive correlation between jaw and neck pain ratings for group 1 (r = 0.61, P neck pain and disability compared with controls. Taken together, the results show that individuals with a recent whiplash trauma report more jaw pain and disability compared with controls without a history of neck trauma. Furthermore, the correlation between jaw and neck pain intensity implies that intensity of neck pain in the acute stage after whiplash trauma might be a possible risk factor also for development of chronic orofacial pain. © International & American Associations for Dental Research 2016.

  6. The influence of jaw's curvature on the results of the Brazilian disc test

    Directory of Open Access Journals (Sweden)

    Ch.F. Markides

    2016-04-01

    Full Text Available The general contact problem of a disc squeezed between jaws of arbitrary curvature is considered employing Muskhelishvili's complex potentials. Taking advantage of the general solution introduced, the closed-form expressions for the stresses along strategic loci (loaded rim, loaded diameter, disc's center are obtained, in terms of the ratio ρ of the disc's to the jaw's curvature. Then, the effect of ρ (as well as that of the relative stiffness of the disc's and jaw's materials dictating the contact arc on the stress distribution along these loci is explored. It is concluded that, for both smooth contact (zero friction and contact with friction, the role of the jaw's curvature is significant not only along the disc-jaw contact arc (as it could be expected, but also all along the loaded diameter. On the other hand, it is indicated that the stress field at the disc's center is more or less insensitive to the jaw's curvature assuming that ρ lies within the range (0, 0.67 or in other words within the limits defined by the two standardized suggestions, i.e. that of American Society for Testing and Materials (ASTM (plane loading platens with ρ = 0 and that of International Society for Rock Mechanics (ISRM (curved jaws with ρ = 0.67. The upper limit of this range is a kind of compromise between the need to make the stress field at the disc's center independent of the boundary conditions while keeping at the same time the contact angle large enough to reduce the stress concentration and the risk for premature fracture initiation far from the disc's center. For jaws with radius of curvature exceeded by that suggested by ISRM, the stress field at the disc's center is significantly influenced. Especially for jaws with radius approaching that of the disc, the stress field at the disc's center is dramatically distorted rendering Hondros' formula inapplicable and the test results erroneous.

  7. Windowed SHE-PWM of Interleaved Four-Quadrant Converters for Resonance Suppression in Traction Power Supply Systems

    DEFF Research Database (Denmark)

    Song, Kejian; Konstantinou, Georgios; Mingli, Wu

    2017-01-01

    AC electric locomotives that use a number of interleaved four-quadrant converters generate high-frequency switching harmonics which may stimulate certain resonances in traction power supply systems (TPSSs). A windowed selective harmonic elimination pulse-width modulation (SHE-PWM) method...... is proposed to suppress such resonances. Owing to the windowed design and the precalculated solutions, the proposed method covers the wide potential resonant frequency range and addresses the resonant frequency variation while keeping the low switching frequency of the traction converters. The proposed...... windowed SHE-PWM is fully tested with a closed-loop controller in a simulation model with the TPSS and the ac electric locomotive. Comparative simulation results show that the windowed SHE-PWM is an effective alternative that overcomes the resonance suppression limitations of the conventional phase...

  8. Double-Quadrant State-of-Charge-Based Droop Control Method for Distributed Energy Storage Systems in Autonomous DC Microgrids

    DEFF Research Database (Denmark)

    Lu, Xiaonan; Sun, Kai; Guerrero, Josep M.

    2015-01-01

    In this paper, a double-quadrant state-of-charge (SoC) based droop control method for distributed energy storage system (DESS) is proposed to reach the proper power distribution in autonomous DC microgrids. Since DESS is commonly used in DC microgrids, it is necessary to achieve the rational power...... sharing in both charging and discharging process. In order to prolong the lifetime of the energy storage units (ESUs) and avoid the overuse of a certain unit, the SoC of each unit should be balanced and the injected/output power should be gradually equalized. Droop control as a decentralized approach...... is used as the basis of the power sharing method for distributed energy storage units (DESUs). In the charging process, the droop coefficient is set to be proportional to the nth order of SoC, while in the discharging process, the droop coefficient is set to be inversely proportional to the nth order...

  9. High performance control strategy for single-phase three-level neutral-point-clamped traction four-quadrant converters

    DEFF Research Database (Denmark)

    Kejian, Song; Konstantinou, Georgios; Jing, Li

    2017-01-01

    multiple unit traction system is proposed in this study. The strategy is based on a multiple frequency tuned quasi-proportional resonant controller in the ac-side current loop and a multiple frequency tuned notch filter in the dc-link voltage loop. Under the typical supply voltage distortion present......Operational data from Chinese railways indicate a number of challenges for traction four-quadrant converter (4QC) control including low-order voltage and current harmonics and reference tracking. A control strategy for a single-phase three-level neutral-point-clamped 4QC employed in the electric...... in the network, the proposed control strategy improves the current tracking performance and reduces the line current harmonics, when compared with conventional control strategies. Experimental results, both under purely sinusoidal and distorted supply voltages, validate the effectiveness of the proposed control...

  10. Decoupled Power Solution for Dual-input Isolated DC-DC Converters Using Four Quadrants Integrated Transformers (FQIT)

    DEFF Research Database (Denmark)

    Ouyang, Ziwei; Andersen, Michael A. E.; Thomsen, Ole Cornelius

    2012-01-01

    ) space orthogonal flux is proposed in this paper. And thus a new geometry core and relative winding arrangements are proposed in accordance with the rthogonal flux decoupling technology. Due to the four secondary windings are arranged in a quadratic pattern at the base core plate with the two...... perpendicular primary windings, a name of “four quadrants integrated transformers” (FQIT) is therefore given to the proposed construction. Since the two primary windings are uncoupled, the FQIT allows the two input power stages to transfer the energy into the output load simultaneously or at any...... timemultiplexing scheme, which can optimize the utilization of diversified power energy sources, simplify the system structure, improve the flexibility and reduce the overall cost, so they are attractive for the hybrid renewable power system. Section IV initiates a discussion for the advantages of the FQIT...

  11. Upper quadrant port placement for robot-assisted renal surgery: implementation of the Floating Arm and the XL Protype.

    Science.gov (United States)

    Totonchi, Samer; Elgin, Robert; Monahan, Michael; Johnston, William K

    2014-08-01

    Abstract Background and Purpose: Placement of the fourth arm (4th arm) in the lower quadrant (LQ) is commonly described for robot-assisted renal surgical procedures but has anatomic restrictions and limited ergonomics. An alternative, upper quadrant (UQ) location is desirable, but patient habitus and spacing may restrict robotic attachment. We investigate current trends in 4th arm port placement and propose an alternative method at attaching the robot-the "Floating Arm" (FLA). Robotic surgeons from the Endourological Society were surveyed. A 20-cm extra-long (XL Protype) da Vinci instrument was developed for the FLA technique. A dry lab allowed quantitative comparison of spacing and ranges of motion for standard da Vinci ports (dVP), bariatric dVP, telescoping dVP, and FLA. There were 108 respondents who participated. Half of the respondents avoid using the 4th arm (30% lack of need and 20% because of interference). The majority (90%) typically positions the 4th arm in the LQ, but many reported limitations in this location. Few (5%) place 4th arm in the UQ, while most (73%) have never heard of UQ placement. Existing techniques may increase shoulder height clearance but inversely shorten the working length of the instrument intracorporeally. Alternatively, the XL Protype significantly increased the shoulder length and maintained available working distances intracorporeally. Adjacent arm interference angle was essentially identical (27 degrees) for all ports except a greater range of movement for the XL Protype (35 degrees). Few surgeons are using an UQ positioning or use techniques to improve attachment of the 4th arm. The greatest freedom may be obtained by implementing the FLA, but this necessitates production of a longer instrument.

  12. Potential climate change effects on the habitat of antarctic krill in the weddell quadrant of the southern ocean.

    Science.gov (United States)

    Hill, Simeon L; Phillips, Tony; Atkinson, Angus

    2013-01-01

    Antarctic krill is a cold water species, an increasingly important fishery resource and a major prey item for many fish, birds and mammals in the Southern Ocean. The fishery and the summer foraging sites of many of these predators are concentrated between 0° and 90°W. Parts of this quadrant have experienced recent localised sea surface warming of up to 0.2°C per decade, and projections suggest that further widespread warming of 0.27° to 1.08°C will occur by the late 21(st) century. We assessed the potential influence of this projected warming on Antarctic krill habitat with a statistical model that links growth to temperature and chlorophyll concentration. The results divide the quadrant into two zones: a band around the Antarctic Circumpolar Current in which habitat quality is particularly vulnerable to warming, and a southern area which is relatively insensitive. Our analysis suggests that the direct effects of warming could reduce the area of growth habitat by up to 20%. The reduction in growth habitat within the range of predators, such as Antarctic fur seals, that forage from breeding sites on South Georgia could be up to 55%, and the habitat's ability to support Antarctic krill biomass production within this range could be reduced by up to 68%. Sensitivity analysis suggests that the effects of a 50% change in summer chlorophyll concentration could be more significant than the direct effects of warming. A reduction in primary production could lead to further habitat degradation but, even if chlorophyll increased by 50%, projected warming would still cause some degradation of the habitat accessible to predators. While there is considerable uncertainty in these projections, they suggest that future climate change could have a significant negative effect on Antarctic krill growth habitat and, consequently, on Southern Ocean biodiversity and ecosystem services.

  13. CT differentiation of periappendiceal inflammation with appendicitis and pelvic inflammatory disease in woman with right lower quadrant pain

    International Nuclear Information System (INIS)

    Wang, Hyun Hye; Kim, Mi Young; Kim, Jung Eun; Kim, Youn Jeong; Suh, Chang Hae

    2006-01-01

    We wanted to determine the usefulness of the computed tomography (CT) findings for making the diagnosis between periappendiceal inflammation (PAI) with appendicitis and pelvic inflammatory disease (PID) for the women presenting with right lower quadrant pain. We retrospectively analyzed the CT findings of 83 women with right lower quadrant pain: PAI in 36 and PID in 47 patients. We reviewed the CT images, including the appendiceal diameter and the enhancing wall thickening, the cecal thickening, the location of the appendix, thickening of the right anterior renal fascia, abscess, mesenteric fatty infiltration, ascites, heterogeneous uterine enhancement and paralytic ileus. Statistical analysis was performed by using the t-test for the diameter of appendix, and the x 2 test or Fisher's exact test for the CT findings. The mean diameter of the appendix was 11.0 ± 3.4 mm for the PAI subjects and it was 6.7 ± 2.0 mm for the PID subjects (ρ < 0.0001). Wall thickening of the appendix was more commonly detected in PAI (25 subjects, 69%) than in PID (15 subjects, 32%) (ρ = 0.0007). Thickening of the right anterior renal fascia was more commonly detected in PAI (18 subjects, 50%) than in PID (7 subjects, 15%). Cecal thickening, ascitis, heterogeneous uterine enhancement and paralytic ileus were not significantly different between PAI and PID. Abscess and mesenteric fatty infiltration were more frequently detected in the RLQ and in the abdomen or pelvic cavity in PAI and PID, respectively (ρ < 0.05). There was no significant difference in the distribution of ascites between the diseases. The CT findings of the appendiceal diameter, enhancing wall thickening and thickening of the right anterior renal fascia are useful for making the diagnosis of PAI. The abdominal and pelvic distributions of abscess and mesenteric fatty infiltration are highly suggestive findings of PID

  14. Potential climate change effects on the habitat of antarctic krill in the weddell quadrant of the southern ocean.

    Directory of Open Access Journals (Sweden)

    Simeon L Hill

    Full Text Available Antarctic krill is a cold water species, an increasingly important fishery resource and a major prey item for many fish, birds and mammals in the Southern Ocean. The fishery and the summer foraging sites of many of these predators are concentrated between 0° and 90°W. Parts of this quadrant have experienced recent localised sea surface warming of up to 0.2°C per decade, and projections suggest that further widespread warming of 0.27° to 1.08°C will occur by the late 21(st century. We assessed the potential influence of this projected warming on Antarctic krill habitat with a statistical model that links growth to temperature and chlorophyll concentration. The results divide the quadrant into two zones: a band around the Antarctic Circumpolar Current in which habitat quality is particularly vulnerable to warming, and a southern area which is relatively insensitive. Our analysis suggests that the direct effects of warming could reduce the area of growth habitat by up to 20%. The reduction in growth habitat within the range of predators, such as Antarctic fur seals, that forage from breeding sites on South Georgia could be up to 55%, and the habitat's ability to support Antarctic krill biomass production within this range could be reduced by up to 68%. Sensitivity analysis suggests that the effects of a 50% change in summer chlorophyll concentration could be more significant than the direct effects of warming. A reduction in primary production could lead to further habitat degradation but, even if chlorophyll increased by 50%, projected warming would still cause some degradation of the habitat accessible to predators. While there is considerable uncertainty in these projections, they suggest that future climate change could have a significant negative effect on Antarctic krill growth habitat and, consequently, on Southern Ocean biodiversity and ecosystem services.

  15. Fine needle aspiration cytology in a case of fibrous dysplasia of jaw.

    Science.gov (United States)

    Gupta, Nalini; Gupta, Ruchi; Bakshi, Jaimanti; Rajwanshi, Arvind

    2009-12-01

    Fibro-osseous lesions of the jaw comprise of a spectrum of diseases which include osseous dysplasia, fibrous dysplasia, and ossifying fibroma. The differentiation amongst these individual pathological lesions is difficult and a combined clinico-radiological and histological correlation is essential for exact categorization. Fine needle aspiration cytology (FNAC) is frequently carried out to distinguish between benign and malignant lesions of the jaw as is a quick and reliable modality of investigation which guides in further management. We report, a case of a jaw swelling in a young male, diagnosed as fibrous dysplasia on FNAC.

  16. Jaw mobility changes in patients with upper aerodigestive tract cancer undergoing radiation therapy.

    Science.gov (United States)

    Bragante, Karoline; Wienandts, Patrícia; Mozzini, Carolina; Pinto, Rosélie; da Motta, Neiro; Jotz, Geraldo

    2015-11-01

    Radiation therapy is a therapeutic modality widely used for treatment of upper aerodigestive tract (UADT) neoplasms. However, its action is not restricted to tumor cells, and it may cause a variety of adverse reactions, including reduced jaw mobility. A prospective cohort study was conducted to assess changes in jaw mobility in patients with UADT cancer undergoing radiation therapy. Fifty-six patients completed the study. The results showed a significant reduction in mouth opening (pcancer experience reduced jaw mobility after radiation therapy, which is strongly correlated with mucositis and reduced functional ability.

  17. REHABILITATION OF SEVERELY ATROPHIED UPPER JAW WITH INTRAOSSAL DENTAL IMPLANTS - clinical case

    OpenAIRE

    Ivan Chenchev; Radka Cholakova; Cvetan Cvetanov; Ir. Mitarcheva

    2010-01-01

    Objective: The purpose of this presentation is to show the difficulty in prosthetization of a clinical case with a pronounced atrophy of the upper jaw and the various types and nature of restrictions imposed by the requirements of the patient. Methods: The clinical analysis, surgical protocol and prosthetic solution are presented in the treatment of 72 year-old woman with a pronounced atrophy of the upper jaw. OPG, standard CT of the upper jaw was used in the planning and a special surgical t...

  18. Tooth axis and skeletal structures in mandibular molar vertical sections in jaw deformity with facial asymmetry using MPR images

    International Nuclear Information System (INIS)

    Nojima, Kunihiko; Yokose, Taishi; Ishii, Takenobu; Kobayashi, Makoto; Nishii, Yasushi

    2007-01-01

    The objective of the present study was to investigate frontal morphological asymmetry in the mandibular molar region in terms of tooth axis and skeletal structures using vertical MPR sections in jaw deformity accompanied by facial asymmetry. Subjects consisted of 15 patients with jaw deformity accompanied by facial asymmetry aged 17.4 years to 37.8 years. There were four men and eleven women. Based on X-ray computed tomography (CT) scans, Digital Imaging and Communications in Medicine (DICOM) viewer software was used to prepare multiplanar reconstruction (MPR) sections. The mandible was then positioned on a reference plane based on the menton and left and right gonions, and a vertical MPR section passing through the mesial root of the first mandibular molar was prepared. The following measurements were made on both the shifted and non-shifted sides: maximum buccolingual width of the mandibular body; height of the mandibular body; inclination angle of the mandibular body; degree of buccal protrusion of the mandibular body; and inclination angle of the buccolingual tooth axis of the first molar. Furthermore, degree of median deviation in the menton was measured using frontal cephalograms. Differences in morphological parameters between the shifted and non-shifted sides were assessed. Furthermore, the relationship between median deviation and asymmetry were statistically analyzed. There was no significant asymmetry in the maximum buccolingual width of the mandibular body, the height of the mandibular body or the degree of buccal protrusion of the mandibular body. However, when compared to the shifted side, the inclination angle of the buccolingual tooth axis of the first molar for the non-shifted side was significantly greater. There was a relatively strong correlation between median deviation and inclination angle of the mandibular body. The above findings clarified that, in orthognathic surgery for jaw deformity accompanied by facial asymmetry, actively improving

  19. Non-exposed variant of bisphosphonate-related osteonecrosis of the jaw (BRONJ with a plasmacytoma: A rare case report

    Directory of Open Access Journals (Sweden)

    Arvind Muthukrishnan

    2015-01-01

    Full Text Available Bisphoshonate-related osteonecrosis of the jaw (BRONJ is an avascular osteo-chemonecrosis of the jaw which results after administration of the group of drugs called as bisphosphonates. Bisphosphonates are given to prevent bone resorption in osteolytic diseases such as Paget′s, osteoporosis, osteogenic carcinoma, and other carcinomas where there could be metastasis and bone resorption. Incidence of BRONJ is reported to be high in western literature and is found to be more after intravenous route compared to oral route of administration. There are various clinical stages of BRONJ as per the American Association of Oral and Maxillofacial Surgeons (AAOMS. Here, we present a rare case of a 60-year-old lady who presented with a complaint of a painless swelling in the alveolus and gingiva in the left maxillary posterior region. This patient was on intravenous Zolendronate for more than 4 years. Thorough examination with detailed investigations revealed BRONJ along with a coexisting second primary tumor, plasmacytoma. Metastasis to distant site is a common feature of malignancy. A metastatic lesion usually occurs within 6 months to 1 year after treatment of a primary lesion. Any fresh neoplasm beyond 1 or 2 years after detection of a primary can be regarded as a second primary tumor. Solitary bone plasmacytoma is a localized form of plasma cell tumor. Diagnosis is based on the presence of the following: Malignant proliferation of plasma cells in biopsy, absence of osteolytic bone lesion, absence of Bence Jones proteins, low concentration of monoclonal proteins, elevated IgG and gamma globulin levels.

  20. [Recurrent left atrial myxoma].

    Science.gov (United States)

    Moreno Martínez, Francisco L; Lagomasino Hidalgo, Alvaro; Mirabal Rodríguez, Roger; López Bermúdez, Félix H; López Bernal, Omaida J

    2003-01-01

    Primary cardiac tumors are rare. Mixomas are the most common among them; 75% are located in the left atrium, 20% in the right atrium, and the rest in the ventricles. The seldom appear in atrio-ventricular valves. Recidivant mixoma are also rare, appearing in 1-5% of all patients that have undergone surgical treatment of a mixoma. In this paper we present our experience with a female patient, who 8 years after having been operated of a left atrial mixoma, began with symptoms of mild heart failure. Transthoracic echocardiography revealed recurrence of the tumor, and was therefore subjected to a second open-heart surgery from which she recovered without complications.

  1. Repeated tongue lift movement induces neuroplasticity in corticomotor control of tongue and jaw muscles in humans.

    Science.gov (United States)

    Komoda, Yoshihiro; Iida, Takashi; Kothari, Mohit; Komiyama, Osamu; Baad-Hansen, Lene; Kawara, Misao; Sessle, Barry; Svensson, Peter

    2015-11-19

    This study investigated the effect of repeated tongue lift training (TLT) on the excitability of the corticomotor representation of the human tongue and jaw musculature. Sixteen participants performed three series of TLT for 41 min on each of 5 consecutive days. Each TLT series consisted of two pressure levels (5 kPa and 10 kPa). All participants underwent transcranial magnetic stimulation (TMS) and electromyographic (EMG) recordings of motor evoked potentials (MEPs) in four sessions: (1) before TLT on Day 1 (baseline), (2) after TLT on Day 1, (3) before TLT on Day 5, and (4) after TLT on Day 5. EMG recordings from the left and right tongue dorsum and masseter muscles were made at three pressure levels (5 kPa, 10 kPa, 100% tongue lift), and tongue, masseter, and first dorsal interosseous (FDI) MEPs were measured. There were no significant day-to-day differences in the tongue pressure during maximum voluntary contractions. The amplitudes and thresholds of tongue and masseter MEPs after TLT on Day 5 were respectively higher and lower than before TLT on Day 1 (P<0.005), and there was also a significant increase in tongue and masseter MEP areas; no significant changes occurred in MEP onset latencies. FDI MEP parameters (amplitude, threshold, area, latency) were not significantly different between the four sessions. Our findings suggest that repeated TLT can trigger neuroplasticity reflected in increased excitability of the corticomotor representation of not only the tongue muscles but also the masseter muscles. Copyright © 2015. Published by Elsevier B.V.

  2. Fibrous dysplasia of the jaws associated with secondary hyperparathyroidism: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Whi, Jung Hyun; Kim, Young Joo; Chun, Kyung Ah; Kim, Ki Tae; Chang, Eun Deok; Kim, Young Ok; Lee, Won [The Catholic University of Korea, Uijongbu (Korea, Republic of)

    2007-06-15

    There have been few reports on fibrous dyplasia associated with secondary hyperparathyroidism. We report a case of a hemodialysis patient with secondary hyperparathyroidism concomitant with fibrous dysplasia of the jaws causing an abnormal deformity.

  3. Fibrous dysplasia of the jaws associated with secondary hyperparathyroidism: a case report

    International Nuclear Information System (INIS)

    Whi, Jung Hyun; Kim, Young Joo; Chun, Kyung Ah; Kim, Ki Tae; Chang, Eun Deok; Kim, Young Ok; Lee, Won

    2007-01-01

    There have been few reports on fibrous dyplasia associated with secondary hyperparathyroidism. We report a case of a hemodialysis patient with secondary hyperparathyroidism concomitant with fibrous dysplasia of the jaws causing an abnormal deformity

  4. Imaging characteristics of benign, malignant, and infectious jaw lesions: a pictorial review.

    Science.gov (United States)

    Meyer, Kathleen A; Bancroft, Laura W; Dietrich, Thomas J; Kransdorf, Mark J; Peterson, Jeffrey J

    2011-09-01

    The purpose of this article is to describe the indications and appropriate imaging studies for various jaw tumors and tumorlike lesions, the imaging findings, the differential diagnosis, and appropriate treatment options. It is important for radiologists to recognize the indications and appropriate imaging studies for various jaw lesions. Radiography is typically used for first-line imaging. If necessary, it is followed by CT for evaluation of osseous lesions and MRI for characterization of soft-tissue lesions.

  5. Clinicopathologic Study of Intra- Osseous Lesions of the Jaws in Southern Iranian Population

    OpenAIRE

    Jaafari-Ashkavandi, Zohreh; Akbari, Behrooz

    2017-01-01

    Statement of the Problem: It is necessary for surgeons and practitioners to know about relative incidence and clinicopathologic features of lesions for accurate diagnosis and approach of pathologic lesions. Data are limited about overall incidence of intra-osseous lesions of the jaws in Iranian patients. Purpose: This study evaluated the clinicopathologic features of intra- osseous lesions of the jaws in an Iranian population, in a 22-year period. Materials and Method: In this cross- sectiona...

  6. Comparison of skin-sparing mastectomy using LigaSure? Small Jaw and electrocautery

    OpenAIRE

    Chang, Young Woo; Kim, Hwan Soo; Jung, Seung Pil; Woo, Sang Uk; Lee, Jae Bok; Bae, Jeoung Won; Son, Gil Soo

    2017-01-01

    Background Skin-sparing mastectomy (SSM) is increasingly used in patients with breast cancer. We compared the differences between use of electrocautery and LigaSure? Small Jaw in patients with breast cancer who underwent SSM. Methods Between January 2012 and December 2015, 81 patients with breast cancer who underwent SSM were selected and were divided into the electrocautery group and the LigaSure? Small Jaw group based on the devices that were used. Clinicopathological characteristics, body ...

  7. Osteonecrosis of the jaw and use of bisphosphonates in adjuvant breast cancer treatment: a metanalysis

    OpenAIRE

    Mauri, Davide; Valachis, Antonis; Polyzos, Ilias P.; Polyzos, Nikolaos P.; Kamposioras, Konstantinos; Pesce, Lorenzo L.

    2009-01-01

    Abstract To estimate the cumulative randomized evidence for the overall incidence of bisphosphonates induced jaw osteonecrosis in adjuvant treatment of breast cancer. Systematic review and meta-analysis of randomized clinical trials. Trials were located through PubMed, ISI, Cochrane Library, and major cancer scientific meetings searches. We identified 15 studies reporting data on osteonecrosis of the jaw. A total of 10,694 randomized women were included, of whom 5,312 received bisp...

  8. Zoledronate effects on systemic and jaw osteopenias in ovariectomized periostin-deficient mice.

    Directory of Open Access Journals (Sweden)

    Nicolas Bonnet

    Full Text Available Osteoporosis and periodontal disease (PD are frequently associated in the elderly, both concurring to the loss of jaw alveolar bone and finally of teeth. Bisphosphonates improve alveolar bone loss but have also been associated with osteonecrosis of the jaw (ONJ, particularly using oncological doses of zoledronate. The effects and therapeutic margin of zoledronate on jaw bone therefore remain uncertain. We reappraised the efficacy and safety of Zoledronate (Zol in ovariectomized (OVX periostin (Postn-deficient mice, a unique genetic model of systemic and jaw osteopenia. Compared to vehicle, Zol 1M (100 µg/kg/month and Zol 1W (100 µg/kg/week for 3 months both significantly improved femur BMD, trabecular bone volume on tissue volume (BV/TV and cortical bone volume in both OVX Postn(+/+ and Postn(-/- (all p<0.01. Zol 1M and Zol 1W also improved jaw alveolar and basal BV/TV, although the highest dose (Zol 1W was less efficient, particularly in Postn(-/-. Zol decreased osteoclast number and bone formation indices, i.e. MAR, MPm/BPm and BFR, independently in Postn(-/- and Postn(+/+, both in the long bones and in deep jaw alveolar bone, without differences between Zol doses. Zol 1M and Zol 1W did not reactivate inflammation nor increase fibrous tissue in the bone marrow of the jaw, whereas the distance between the root and the enamel of the incisor (DRI remained high in Postn(-/- vs Postn(+/+ confirming latent inflammation and lack of crestal alveolar bone. Zol 1W and Zol 1M decreased osteocyte numbers in Postn(-/- and Postn(+/+ mandible, and Zol 1W increased the number of empty lacunae in Postn(-/-, however no areas of necrotic bone were observed. These results demonstrate that zoledronate improves jaw osteopenia and suggest that in Postn(-/- mice, zoledronate is not sufficient to induce bone necrosis.

  9. Embryology of the lamprey and evolution of the vertebrate jaw: insights from molecular and developmental perspectives.

    OpenAIRE

    Kuratani, S; Nobusada, Y; Horigome, N; Shigetani, Y

    2001-01-01

    Evolution of the vertebrate jaw has been reviewed and discussed based on the developmental pattern of the Japanese marine lamprey, Lampetra japonica. Though it never forms a jointed jaw apparatus, the L. japonica embryo exhibits the typical embryonic structure as well as the conserved regulatory gene expression patterns of vertebrates. The lamprey therefore shares the phylotype of vertebrates, the conserved embryonic pattern that appears at pharyngula stage, rather than representing an interm...

  10. Jaws calibration method to get a homogeneous distribution of dose in the junction of hemi fields

    International Nuclear Information System (INIS)

    Cenizo de Castro, E.; Garcia Pareja, S.; Moreno Saiz, C.; Hernandez Rodriguez, R.; Bodineau Gil, C.; Martin-Viera Cueto, J. A.

    2011-01-01

    Hemi fields treatments are widely used in radiotherapy. Because the tolerance established for the positioning of each jaw is 1 mm, may be cases of overlap or separation of up to 2 mm. This implies heterogeneity of doses up to 40% in the joint area. This paper presents an accurate method of calibration of the jaws so as to obtain homogeneous dose distributions when using this type of treatment. (Author)

  11. Comparative and developmental functional morphology of the jaws of living and fossil gars (Actinopterygii: Lepisosteidae).

    Science.gov (United States)

    Kammerer, Christian F; Grande, Lance; Westneat, Mark W

    2006-09-01

    The feeding mechanism of gars (Ginglymodi : Lepisosteidae) is characterized by cranial elevation and lower jaw rotation but minimal cranial kinesis. Gar jaws have numerous, sharply pointed, elongate teeth for capture of evasive prey. Their mandibles range from relatively short to extremely long depending on the species. Jaw length and lever dimensions were hypothesized to affect the biomechanics of force and motion during feeding, according to simple mechanical models of muscles exerting force through first- or third-order levers. A morphometric protocol was used to measure the jaw structure of seven living and five fossil species of gar and these data were used to calculate the mechanical advantage (a measure of force transmission) for both opening and closing of the mandible. Gars were found to possess low mechanical advantage (MA) and high transmission of motion, although gars occupy a range of biomechanical states across the continuum of force vs. velocity transmission. The long-nose gar, Lepisosteus osseus, has one of the lowest jaw closing MAs (0.05) ever measured in fishes. Intraspecific lever mechanics were also calculated for a developmental series (from feeding larvae to adults) of L. osseus and Atractosteus spatula. A characteristic ontogenetic curve in MA of the lower jaw was obtained, with a large decrease in MA between larva and juvenile, followed by a steady increase during adult growth. This curve correlates with a change in prey type, with the small, robust-jawed individuals feeding mainly on crustaceans and insects and the large, long-jawed individuals of all species becoming mainly piscivorous. Principal components analysis of functionally important morphometrics shows that several gar species occupy different regions of functional morphospace. Some fossil gar species are also placed within functional morphospace using this approach. (c) 2004 Wiley-Liss, Inc.

  12. Left atrial appendage occlusion

    Directory of Open Access Journals (Sweden)

    Ahmad Mirdamadi

    2013-01-01

    Full Text Available Left atrial appendage (LAA occlusion is a treatment strategy to prevent blood clot formation in atrial appendage. Although, LAA occlusion usually was done by catheter-based techniques, especially percutaneous trans-luminal mitral commissurotomy (PTMC, it can be done during closed and open mitral valve commissurotomy (CMVC, OMVC and mitral valve replacement (MVR too. Nowadays, PTMC is performed as an optimal management of severe mitral stenosis (MS and many patients currently are treated by PTMC instead of previous surgical methods. One of the most important contraindications of PTMC is presence of clot in LAA. So, each patient who suffers of severe MS is evaluated by Trans-Esophageal Echocardiogram to rule out thrombus in LAA before PTMC. At open heart surgery, replacement of the mitral valve was performed for 49-year-old woman. Also, left atrial appendage occlusion was done during surgery. Immediately after surgery, echocardiography demonstrates an echo imitated the presence of a thrombus in left atrial appendage area, although there was not any evidence of thrombus in pre-pump TEE. We can conclude from this case report that when we suspect of thrombus of left atrial, we should obtain exact history of previous surgery of mitral valve to avoid misdiagnosis clotted LAA, instead of obliterated LAA. Consequently, it can prevent additional evaluations and treatments such as oral anticoagulation and exclusion or postponing surgeries including PTMC.

  13. Cone beam computed tomography and ultrasonography imaging of benign intraosseous jaw lesion: a prospective radiopathological study.

    Science.gov (United States)

    Bayrakdar, Ibrahim Sevki; Yilmaz, Ahmet Berhan; Caglayan, Fatma; Ertas, Umit; Gundogdu, Cemal; Gumussoy, Ismail

    2017-10-18

    We assessed whether ultrasonography (US) can be used in combination with cone beam computed tomography (CBCT) to image intraosseous jaw lesions. Using CBCT and US, we evaluated 123 lytic intraosseous jaw lesions diagnosed in 121 patients with guidance from the CBCT findings. The lesions were classified into two groups based on histopathological evaluation: (1) cysts and (2) tumors and tumor-like lesions. US and histopathological findings on the lesions of the two groups and their relationships with each other were also assessed. Results are reported as means ± standard errors, and p lesions were evaluated; 74 (60.2%) were cysts and 49 (39.8%) were tumors or tumor-like lesions. The CBCT and US findings were compatible as far as dimensional measurements of the lesions in the three planes (p lesions correlated (p jaw lesions. Because it offers no valid Hounsfield unit (HU) value, it does not differentiate between solid and cystic masses. Thus, US can be used with CBCT to image intraosseous jaw lesions caused by buccal cortical thinning or perforation. US provides useful information about intraosseous jaw lesions and can be used with CBCT to image such lesions caused by buccal cortical thinning or perforation. Clinicians can take this information into consideration when evaluating intraosseous jaw pathology.

  14. Comparative jaw muscle anatomy in kangaroos, wallabies, and rat-kangaroos (marsupialia: macropodoidea).

    Science.gov (United States)

    Warburton, Natalie Marina

    2009-06-01

    The jaw muscles were studied in seven genera of macropodoid marsupials with diets ranging from mainly fungi in Potorous to grass in Macropus. Relative size, attachments, and lamination within the jaw adductor muscles varied between macropodoid species. Among macropodine species, the jaw adductor muscle proportions vary with feeding type. The relative mass of the masseter is roughly consistent, but grazers and mixed-feeders (Macropus and Lagostrophus) had relatively larger medial pterygoids and smaller temporalis muscles than the browsers (Dendrolagus, Dorcopsulus, and Setonix). Grazing macropods show similar jaw muscle proportions to "ungulate-grinding" type placental mammals. The internal architecture of the jaw muscles also varies between grazing and browsing macropods, most significantly, the anatomy of the medial pterygoid muscle. Potoroines have distinctly different jaw muscle proportions to macropodines. The masseter muscle group, in particular, the superficial masseter is enlarged, while the temporalis group is relatively reduced. Lagostrophus fasciatus is anatomically distinct from other macropods with respect to its masticatory muscle anatomy, including enlarged superficial medial pterygoid and deep temporalis muscles, an anteriorly inflected masseteric process, and the shape of the mandibular condyle. The enlarged triangular pterygoid process of the sphenoid bone, in particular, is distinctive of Lagsotrophus. (c) 2009 Wiley-Liss, Inc.

  15. Evidence for the prepattern/cooption model of vertebrate jaw evolution.

    Science.gov (United States)

    Cerny, Robert; Cattell, Maria; Sauka-Spengler, Tatjana; Bronner-Fraser, Marianne; Yu, Feiqiao; Medeiros, Daniel Meulemans

    2010-10-05

    The appearance of jaws was a turning point in vertebrate evolution because it allowed primitive vertebrates to capture and process large, motile prey. The vertebrate jaw consists of separate dorsal and ventral skeletal elements connected by a joint. How this structure evolved from the unjointed gill bar of a jawless ancestor is an unresolved question in vertebrate evolution. To understand the developmental bases of this evolutionary transition, we examined the expression of 12 genes involved in vertebrate pharyngeal patterning in the modern jawless fish lamprey. We find nested expression of Dlx genes, as well as combinatorial expression of Msx, Hand and Gsc genes along the dorso-ventral (DV) axis of the lamprey pharynx, indicating gnathostome-type pharyngeal patterning evolved before the appearance of the jaw. In addition, we find that Bapx and Gdf5/6/7, key regulators of joint formation in gnathostomes, are not expressed in the lamprey first arch, whereas Barx, which is absent from the intermediate first arch in gnathostomes, marks this domain in lamprey. Taken together, these data support a new scenario for jaw evolution in which incorporation of Bapx and Gdf5/6/7 into a preexisting DV patterning program drove the evolution of the jaw by altering the identity of intermediate first-arch chondrocytes. We present this "Pre-pattern/Cooption" model as an alternative to current models linking the evolution of the jaw to the de novo appearance of sophisticated pharyngeal DV patterning.

  16. Temporomandibular pain and jaw dysfunction at different ages covering the lifespan--A population based study.

    Science.gov (United States)

    Lövgren, A; Häggman-Henrikson, B; Visscher, C M; Lobbezoo, F; Marklund, S; Wänman, A

    2016-04-01

    Temporomandibular pain and jaw dysfunction can have a negative effect on daily life, but these conditions are not well recognized in the health care systems. The general aim was to examine the cross-sectional prevalence of frequent temporomandibular pain and jaw dysfunction in men and women across the lifespan. The analysis was based on data from 137,718 individuals (mean age 35 years, SD 22.7) who answered three questions (3Q/TMD) included in the digital health declaration in the Public Dental Health care in the county of Västerbotten, Sweden; Q1: 'Do you have pain in your temple, face, jaw or jaw joint once a week or more?'; Q2: 'Does it hurt once a week or more when you open your mouth or chew?'; and Q3: 'Does your jaw lock or become stuck once a week or more?' The prevalence of frequent temporomandibular pain (Q1) was 5.2% among women and 1.8% among men (p temporomandibular pain and jaw dysfunction varies during the lifespan. For men and women, respectively, symptoms increase during adolescence, peak in middle age and then gradually diminish. The prevalence of these symptoms is significantly higher among women except from the first and last decades of a 100-year lifespan. © 2015 European Pain Federation - EFIC®

  17. Analysis of the In-core Quadrant Power Tilt affected by Burned Fuel Shuffles of WEC Type NPPs in Republic of Korea

    Energy Technology Data Exchange (ETDEWEB)

    Son, Seung-beom; Jeon, Jeong-pyo; Song, Han-seung; Seong, Ki-bong; Lim, Chae-joon [KEPCO Nuclear Fuel, Daejeon (Korea, Republic of)

    2016-10-15

    This paper presents the designed Burned Fuel Shuffles (BFS) and the related results of measured In-core Quadrant Power Tilt (IQPT) in recent cycles of WEC (Westinghouse Electric Company) type NPPs (Nuclear Power Plants) in Republic of Korea. And the IQPT sensitivity results affected by BFS are also analyzed. Excessive core Quadrant Power Tilt (QPT) causes unreliability about designed power distribution and increases peaking factors in the affected core quadrants. The peaking factors are under surveillance during the cycle for the safe operation and the Quadrant Power Tilt Ratio (QPTR) is covered by the Technical Specifications. Possible causes for QPT include manufacturing tolerance, asymmetric core configurations, operating conditions, and so forth, but the actual cause of specific core tilts frequently cannot be definitively identified. But nuclear designer continuously try to minimize the QPT by the general control of burned fuel distribution in a reload core. In this study, the general guidelines of BFSP for effective mitigation of IQPT were introduced by references and the actual states of designed BFSP were analyzed for WEC type plant operating in the Republic of Korea. Results revealed that the BFSP was applied within appropriate level, which keeps IQPT below the level of guideline during the operations. Also, the correlation between BFSP of category 1/3 and IQPT were quantitatively confirmed by the sensitivity analysis concerned with the change of BFSP.

  18. Hypoplastic left heart syndrome

    Directory of Open Access Journals (Sweden)

    Thiagarajan Ravi

    2007-05-01

    Full Text Available Abstract Hypoplastic left heart syndrome(HLHS refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left ventricle, aorta, and aortic arch, as well as mitral atresia or stenosis. HLHS has been reported to occur in approximately 0.016 to 0.036% of all live births. Newborn infants with the condition generally are born at full term and initially appear healthy. As the arterial duct closes, the systemic perfusion becomes decreased, resulting in hypoxemia, acidosis, and shock. Usually, no heart murmur, or a non-specific heart murmur, may be detected. The second heart sound is loud and single because of aortic atresia. Often the liver is enlarged secondary to congestive heart failure. The embryologic cause of the disease, as in the case of most congenital cardiac defects, is not fully known. The most useful diagnostic modality is the echocardiogram. The syndrome can be diagnosed by fetal echocardiography between 18 and 22 weeks of gestation. Differential diagnosis includes other left-sided obstructive lesions where the systemic circulation is dependent on ductal flow (critical aortic stenosis, coarctation of the aorta, interrupted aortic arch. Children with the syndrome require surgery as neonates, as they have duct-dependent systemic circulation. Currently, there are two major modalities, primary cardiac transplantation or a series of staged functionally univentricular palliations. The treatment chosen is dependent on the preference of the institution, its experience, and also preference. Although survival following initial surgical intervention has improved significantly over the last 20 years, significant mortality and morbidity are present for both surgical strategies. As a result pediatric cardiologists continue to be challenged by discussions with families regarding initial decision

  19. Dental implants for severely atrophied jaws due to ectodermal dysplasia

    Directory of Open Access Journals (Sweden)

    Preetha Balaji

    2015-01-01

    Full Text Available The aim was to present the successful esthetical and functional rehabilitation of partial anodontia in a case of severe ectodermal dysplasia with complete atrophy of the jaws. A 17-year-old male with Class III malocclusion with partial anodontia sought dental implant treatment. His expectation was that of Class I occlusion. The challenge in the case was to match the expectation, reality, and the clinical possibilities. Ridge augmentation was performed with a combination of rib graft and recombinant human bone morphogenetic protein-2. Simultaneously, 6 implants (Nobel Biocare™ - Tapered Groovy were placed in maxillary arch and 10 in the mandible. Simultaneous placement ensured faster and better osseointegration though a mild compromise of the primary stability was observed initially. After adequate healing, Customized Zirconia Procera™ system was used to build the framework. Zirconia crown was cemented to the framework. Radiological and clinical evidence of osseointegration was observed in all 16 dental implants. Successful conversion of Class III to Class I occlusion was achieved with the combination of preprosthetic alveolar ridge augmentation, Procera™ Implant Bridge system. Abnormal angulations and or placement of dental implants would result in failure of the implant. Hence conversion of Class III to Class I occlusion needs complete and complex treatment planning so that the entire masticatory apparatus is sufficiently remodeled. Planning should consider the resultant vectors that would otherwise result in failure of framework or compromise the secondary stability of the dental implant during function. A successful case of rehabilitation of complex partial anodontia is presented.

  20. Dental extraction following zoledronate, induces osteonecrosis in rat's jaw.

    Science.gov (United States)

    Vidal-Gutiérrez, X; Gómez-Clavel, J-F; Gaitán-Cepeda, L-A

    2017-03-01

    Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is clinically characterized by the presence of exposed bone in the oral cavity that persists for more than eight weeks. Previous attempts to establish an animal model have not sufficiently considered disease features. Our aim was to establish an inexpensive and replicable animal model that develops BRONJ in a short time. Thirty-two male Wistar rats were randomly divided into two groups: control and experimental. In the experimental group, we administered 0.06mg/kg intraperitoneal dose of zoledronic acid (ZA) 7 and 14 days prior to maxillary second molar extraction. At two, four and six weeks after tooth extraction, the animals were euthanized, and we dissected the maxilla following histological procedures. We stained serial slides with hematoxylin and eosin and Masson's trichrome. The samples were harvested for macroscopic, radiologic and histological evaluation of bone changes. At two weeks postextraction, we observed exposed necrotic bone in dental socket areas in experimental groups. Radiological analysis revealed osteolytic lesions accompanied by extensive destruction and sequestrum formation in the same group. Histological examination confirmed the absence of necrotic bone in control groups in contrast with the experimental groups. The percentage of empty lacunae and the number of osteoclasts and the necrotic bone area were significantly increased (p<0.05) in the experimental groups. The animal model using ZA administration to prior dental extraction successfully mimicked human BRONJ lesions. Also, the model was easily replicated, inexpensive and showed different features than other previous BRONJ models.

  1. Epidemiology and pathogenesis of osteonecrosis of the jaw.

    Science.gov (United States)

    Reid, Ian R; Cornish, Jillian

    2011-11-29

    Osteonecrosis of the jaw (ONJ) is defined as exposed bone in the oral cavity that persists despite appropriate therapy. Over the past decade, ONJ has been reported in about 5% of patients with cancer receiving high-dose intravenous bisphosphonates, and more recently in similar patients treated with denosumab, another potent inhibitor of osteoclastic bone resorption. The condition has also been described in patients treated with bisphosphonates for benign diseases, such as osteoporosis, but whether bisphosphonates or denosumab increase the incidence above that seen in untreated patients of comparable age and frailty is yet to be established. The pathogenesis of ONJ is uncertain: the toxic effects of bisphosphonates in a wide variety of cells could increase susceptibility to infections in the oral cavity or impair mucosal healing, and denosumab might interfere with monocyte and macrophage function. Local osteolysis is an important defense against infection on bone surfaces that is blocked by both bisphosphonates and denosumab. Preventive dentistry prior to high-dose antiresorptive therapy is a critical measure in cancer patients, but is not usually justified in patients with osteoporosis. The management of established ONJ lesions is problematic: the greatest success seems to come from vigorous antimicrobial therapy with judicious use of surgical debridement.

  2. Intraosseous benign lesions of the jaws: a radiographic study.

    Science.gov (United States)

    Javadian Langaroodi, Adineh; Lari, Sima Sadat; Shokri, Abbas; Hoseini Zarch, Seyed Hossein; Jamshidi, Shokofeh; Akbari, Peyman

    2014-01-01

    Benign maxillo-mandibular tumors and cysts, which are relatively common findings on radiographs, namely the ubiquitous panoramic view, have to be dealt with by dentists on a daily basis. The aim of this study is to evaluate the panoramic radiographic findings pertaining to benign and tumoral lesions in the maxilla and mandible. Applying a case series method, panoramic images of 61 patients with cysts, benign tumors and tumor-like lesions in the jaws who were referred to Hamedan dental school between 2009 and 2011 were evaluated by two radiologists. They were both blind to histopathological results as well as the objectives of our study. Lesions were assessed based on their location, periphery, internal structure and impaction on the surrounding structures. Then the obtained data were analyzed using descriptive tables. Cysts were mostly more common in men despite the equal propensity of both genders to benign tumors. In contrast, women showed a higher frequency of tumor-like lesions. The most common site of involvement was the posterior mandible, with peri-apical tooth lesions as the most prevalent dental association. Radiographically, what we most encountered was unilocular radiolucency pertaining to cysts and benign tumors; nevertheless, tumor-like lesions tended to present with a well-defined radiopacity. Despite its known shortcomings, like every other diagnostic tool, panoramic radiography can contribute to the early detection of maxillary/mandibular lesions that in turn enable the dentist to devise an appropriate treatment plan.

  3. Metastatic cervical carcinoma of the jaw presenting as periapical disease.

    Science.gov (United States)

    Torregrossa, V R; Faria, K M; Bicudo, M M; Vargas, P A; Almeida, O P; Lopes, M A; Santos-Silva, A R

    2016-02-01

    To present a case report of a metastasis from cervical cancer to the maxilla, which was misdiagnosed as periapical disease and to caution clinicians that metastases could have a disguised clinical presentation that must be taken into account in the differential diagnosis of periapical disease in oncologic patients. Although metastatic tumours of the jaws are uncommon, they may mimic benign inflammatory processes and reactive lesions. The ability of metastatic lesions to mimic periapical disease is discussed and a brief review of the literature is presented, emphasizing the importance of correct diagnosis to prevent delay in diagnosing cancer. Attention should therefore be given to the patient's medical history, especially of those with a previous history of cancer, and all dental practitioners should be aware of the possibility of metastases that may be confused with periapical disease. Finally, endodontists are well placed to recognize malignant and metastatic oral lesions during the initial clinical stages, given that their treatments are usually based on frequent dental appointments and long-term follow-ups. © 2015 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  4. Intraosseous Benign Lesions of the Jaws: A Radiographic Study

    International Nuclear Information System (INIS)

    Javadian Langaroodi, Adineh; Lari, Sima Sadat; Shokri, Abbas; Hoseini Zarch, Seyed Hossein; Jamshidi, Shokofeh; Akbari, Peyman

    2014-01-01

    Benign maxillo-mandibular tumors and cysts, which are relatively common findings on radiographs, namely the ubiquitous panoramic view, have to be dealt with by dentists on a daily basis. The aim of this study is to evaluate the panoramic radiographic findings pertaining to benign and tumoral lesions in the maxilla and mandible. Applying a case series method, panoramic images of 61 patients with cysts, benign tumors and tumor-like lesions in the jaws who were referred to Hamedan dental school between 2009 and 2011 were evaluated by two radiologists. They were both blind to histopathological results as well as the objectives of our study. Lesions were assessed based on their location, periphery, internal structure and impaction on the surrounding structures. Then the obtained data were analyzed using descriptive tables. Cysts were mostly more common in men despite the equal propensity of both genders to benign tumors. In contrast, women showed a higher frequency of tumor-like lesions. The most common site of involvement was the posterior mandible, with peri-apical tooth lesions as the most prevalent dental association. Radiographically, what we most encountered was unilocular radiolucency pertaining to cysts and benign tumors; nevertheless, tumor-like lesions tended to present with a well-defined radiopacity. Despite its known shortcomings, like every other diagnostic tool, panoramic radiography can contribute to the early detection of maxillary/mandibular lesions that in turn enable the dentist to devise an appropriate treatment plan

  5. Immunoreactivity of granular cell lesions of skin, mucosa, and jaw.

    Science.gov (United States)

    Regezi, J A; Zarbo, R J; Courtney, R M; Crissman, J D

    1989-10-01

    Granular cell lesions from many different sites share similar light and electron microscopic features. Immunologically, however, these lesions do not appear to be a homogenous group. This study determines the extent of immunologic heterogeneity of granular cell lesions from a wide variety of sites in skin, mucosa, and jaw. Thirty-one granular cell lesions (26 granular cell tumors [GCT] and five other granular cell lesions) from 18 different sites were evaluated immunohistochemically for keratins, vimentin, desmin, muscle actin, ACT, HLA-DR, and S-100 protein. Paraffin-embedded sections were utilized with an avidin-biotin complex immunoperoxidase technique. Except for ameloblastomas, all lesions were negative for keratin and positive for vimentin. All lesions were negative for desmin and actin. Positive ACT reactivity was found in one of seven GCT of tongue, a colonic lesion, a nose lesion, and a granular cell ameloblastic fibroma. All lesions were positive for HLA-DR except a few in which fixation appeared inadequate. S-100 immunoreactivity was found in all lesions except the congenital epulis, a GCT of the skin of the nose, a colonic lesion, and the odontogenic tumors. The antigenic profile of GCT of skin and mucosa is consistent with Schwann cell origin. However, some GCT and other granular cell lesions appear to be derived from macrophages, epithelial cells, or other cells. The expression of HLA-DR by granular cells is believed to be unrelated to cellular origin but rather to some common immunologic function.

  6. Ameloblastoma of the jaws: Management and recurrence rate.

    Science.gov (United States)

    Laborde, A; Nicot, R; Wojcik, T; Ferri, J; Raoul, G

    2017-02-01

    Ameloblastoma is a rare, benign odontogenic tumour associated with a high recurrence rate. It accounts for 1% of all tumours of the jaws. The purpose of this study was to compare the ameloblastoma recurrence rate according to the type of treatment: radical or conservative. All patients with a diagnosis of ameloblastoma between 1991 and 2013 were retrospectively identified in order to extract topographic, radiological, and histological data and the type of treatment: conservative (marsupialization, enucleation, curettage) or radical (segmental resection) and to compare the recurrence rate according to the type of treatment. Twenty-seven patients were included, managed by conservative treatment (CT) in 22 cases and radical treatment (RT) in 14 cases. The recurrence rate was 90.9% in the CT group and 9.1% in the RT group (P=0.025) with a mean follow-up of 56.2 months. The recurrence rate after conservative treatment was higher than that after radical treatment. These results are similar to those reported in the literature. The choice of treatment must be adapted to the macroscopic and histological characteristics of each tumour and to the patient. Copyright © 2016. Published by Elsevier Masson SAS.

  7. Examination of jaws and teeth using Dental CT

    International Nuclear Information System (INIS)

    Nikolov, Vl.

    2001-01-01

    The aim of the present work was to establish a new method for dental imaging using Dental CT. Dental computer assisted tomography represents valuable addition to the diagnostics spectrum for planning oral and maxillofacial surgery. High resolution spiral CT and specially designed computer software allow representation of the jaws in different planes that are easy to match. The further allow the display of very small structures relevant to oral surgical interventions and reveal their spatial relationship in three dimensions. Dental CT is indicated, when clinical and conventional radiological techniques will not allow exact interpretation of the situation. It is modern oral implantology that primarily benefits from computer software enabling the assessment of surgical sites in the pre surgical phase. Such planning was not yet possible using two dimensional radiographic techniques. The dental-implantological part expects from radiography sharply defined contours of the external bony contours and the mandibular canal, exactly defined relation between slices and planes, no distortion in the ortho-radial planes, tools for reliable measurements of distances, angles and volumes, possibility to transmit pictures electronically or on hardcopy without loss of quality. Thus communication between dentists and radiologists may and must be intensified and supported by usage of modern telecommunication systems. (author)

  8. Short implants supporting single crowns in atrophic jaws.

    Science.gov (United States)

    Al-Ansari, Asim

    2014-09-01

    PubMed-Medline, Web of Science, Cochrane Library, ProQuest Dissertations and Theses, LILACS, Ebsco-Dentistry and Oral Sciences Source, Scirus, Embase, Scopus and Journal Ovid databases were searched. In addition hand searching of 14 relevant journals was undertaken along with screening of the reference lists of screened article and reviews. Randomised controlled clinical trials (RCTs), controlled clinical trials (CCTs), prospective cohort studies and case series were included. Studies where short (biological failure proportion (BFP), prosthetic failure proportion (PFP) and radiographic marginal bone loss (MBL) were 5.9% (95% CI: 3.7-9.2%), 3.8% (95%CI: 1.9-7.4%), 2.8% (95%CI: 1.4-5.7%) and 0.83 mm (95%CI: 0.54-1.12 mm) respectively. Quantitative analysis showed that placement in the mandible (p = 0.0002) and implants with length ≤ 8 mm (p = 0.01) increased FP, BFP and MBL, whereas qualitative assessment revealed that crown-to-implant ratio did not influence MBL. Within the limitations of the present systematic review with meta-analysis, it is suggested that single crowns supported by short implants are an acceptable and predictable option in the short- and long-term treatment of the atrophic jaws.

  9. Pattern and presentation of odontogenic jaw cysts: a clinical experience

    International Nuclear Information System (INIS)

    Awan, M.U.A.; Ibrahim, M.W.

    2017-01-01

    Objective: To determine the pattern and presentations of odontogenic jaw cysts in patients reporting at the Armed Forces Institute of Dentistry. Study Design: Descriptive study. Place and Duration of Study: Armed Forces Institute of Dentistry, from Jan to Dec 2007. Material and Methods: Hundred patients including 70 males and 30 females with the age range 5-65 years were included in the study. History, clinical examination, radiographic examination and histopathologic examination of lesion were carried out for each patient. A proforma was filled for each patient for all relevant information, presentation and pattern. Diagnosis was confirmed by histopathology. Data were analyzed using SPSS version 10. Results: Out of total 100 patients, 58 percent were diagnosed with radicular cysts, 25 percent with dentigerous cysts, 15 percent with odontogenic keratocyst, 1 percent patient with calcifying epithelial odontogenic cyst and 1 percent patient was diagnosed with eruption cyst. Conclusion: The study demonstrates that radicular cyst was the most common odontogenic cysts followed by dentigerous and odontogenic keratocysts respectively in our study sample. (author)

  10. Hyperparathyroidism-Jaw Tumor Syndrome: Results of surgical management

    Science.gov (United States)

    Mehta, Amit; Patel, Dhaval; Rosenberg, Avi; Boufraqech, Myriem; Ellis, Ryan J.; Nilubol, Naris; Quezado, Martha M.; Marx, Stephen J.; Simonds, William F.; Kebebew, Electron

    2014-01-01

    Background Hyperparathyroidism-jaw tumor syndrome (HPT-JT) is a rare autosomal dominant disease secondary to germline inactivating mutations of the tumor suppressor gene HRPT2/CDC73. The aim of the present study is to determine the optimal surgical approach to parathyroid disease in patients with HPT-JT. Method A retrospective analysis of clinical and genetic features, parathyroid operative outcomes, and disease outcomes in seven unrelated HPT-JT families. Results Seven families had five distinct germline HRPT2/CDC73 mutations. Sixteen affected family members (median age of 30.7 years) were diagnosed with primary hyperparathyroidism. Fifteen of the 16 patients underwent preoperative tumor localization studies and uncomplicated bilateral neck exploration at initial operation - all were in biochemical remission at most recent follow up. 31% of patients had multiglandular involvement. 37.5% of patients developed parathyroid carcinoma (median overall survival 8.9 years; median follow-up 7.4 years). Long-term follow-up showed 20% of patients had recurrent primary hyperparathyroidism. Conclusions Given the high risk of malignancy and multiglandular involvement in our cohort, we recommend bilateral neck exploration and en-bloc resection of parathyroid tumors suspicious for cancer and life-long postoperative follow-up. PMID:25444225

  11. Hyperparathyroidism-jaw tumor syndrome: Results of operative management.

    Science.gov (United States)

    Mehta, Amit; Patel, Dhaval; Rosenberg, Avi; Boufraqech, Myriem; Ellis, Ryan J; Nilubol, Naris; Quezado, Martha M; Marx, Stephen J; Simonds, William F; Kebebew, Electron

    2014-12-01

    Hyperparathyroidism-jaw tumor syndrome (HPT-JT) is a rare, autosomal-dominant disease secondary to germline-inactivating mutations of the tumor suppressor gene HRPT2/CDC73. The aim of the present study was to determine the optimal operative approach to parathyroid disease in patients with HPT-JT. A retrospective analysis of clinical and genetic features, parathyroid operative outcomes, and disease outcomes in 7 unrelated HPT-JT families. Seven families had 5 distinct germline HRPT2/CDC73 mutations. Sixteen affected family members (median age, 30.7 years) were diagnosed with primary hyperparathyroidism (PHPT). Fifteen of the 16 patients underwent preoperative tumor localization studies and uncomplicated bilateral neck exploration at initial operation; all were in biochemical remission at most recent follow-up. Of these patients, 31% had multiglandular involvement; 37.5% of the patients developed parathyroid carcinoma (median overall survival, 8.9 years; median follow-up, 7.4 years). Long-term follow-up showed that 20% of patients had recurrent PHPT. Given the high risk of malignancy and multiglandular involvement in our cohort, we recommend bilateral neck exploration and en bloc resection of parathyroid tumors suspicious for cancer and life-long postoperative follow-up. Published by Elsevier Inc.

  12. FDG-PET/CT in advanced ovarian cancer staging: Value and pitfalls in detecting lesions in different abdominal and pelvic quadrants compared with laparoscopy

    Energy Technology Data Exchange (ETDEWEB)

    De Iaco, Pierandrea [Department of Gynaecology, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy); Musto, Alessandra [Department of Nuclear Medicine, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy); Orazi, Luca [Department of Gynaecology, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy); Zamagni, Claudio; Rosati, Marta [Department of Medical Oncology, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy); Allegri, Vincenzo [Department of Nuclear Medicine, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy); Cacciari, Nicoletta [Department of Medical Oncology, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy); Al-Nahhas, Adil [Department of Nuclear Medicine, Hammersmith Hospital, London (United Kingdom); Rubello, Domenico, E-mail: domenico.rubello@libero.it [Department of Nuclear Medicine, PET/CT Centre, Radiology, Medical Physics, ' Santa Maria della Misericordia' Hospital, Viale Tre Martiri 140, 45100 Rovigo (Italy); Venturoli, Stefano [Department of Gynaecology, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy); Fanti, Stefano [Department of Nuclear Medicine, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna (Italy)

    2011-11-15

    Introduction and aim: Ovarian carcinoma (OC) is a common cancer in the Western Countries, and an important cause of death in patients suffering with gynaecologic malignancies. The majority of patients present with advanced disease at the time of diagnosis. Treatment with debulking surgery followed by chemotherapy is the standard approach while chemotherapy is contemplated when surgery is not possible. A correct pre-operative staging is important to ensure a most appropriate management. Laparoscopy (LPS) is the standard diagnostic tool for the assessment of intraperitoneal infiltration but is invasive and requires general anaesthesia. FDG-PET/CT is increasingly used for staging different types of cancer, and the aim of this study is to assess the value of FDG-PET/CT in staging advanced OC and its sensitivity to detect lesions in different quadrants of the abdominal-pelvic area compared to laparoscopy. Materials and methods: From September 2004 till April 2008, 40 patients with high suspicion of OC were referred to our hospital for diagnostic LPS to explore the possibility of optimal debulking surgery. Those who were not suitable for surgery were referred for chemotherapy. Before chemotherapy, the patients underwent an FDG-PET/CT scan. The findings in 9 quadrants of abdominal-pelvic area (total 360 quadrants) for PET/CT and LPS were recorded and compared. Results: In 14/360 areas (3.8%), surgical evaluation was not possible because of presence of adhesions, thus the number of areas explored by laparoscopy was 346. Tumour was found in 308 quadrants (38 quadrants free of disease). PET/CT was positive in all 40 patients with true negative results in 26/346 quadrants (7.5%), and true positives results in 243/346 quadrants (70.2%). False positive and negative PET/CT results were found in 12/346 and 65/346 quadrants, respectively. False positive PET/CT findings were evenly present in all quadrants. False negative PET/CT findings were present in 31/109 (28.4%) upper

  13. Influence of jaw tracking in intensity-modulated and volumetric-modulated arc radiotherapy for head and neck cancers: a dosimetric study

    Energy Technology Data Exchange (ETDEWEB)

    Mani, Karthick Raj [Research and Development Centre, Bharathiar University, Tamilnadu (India); Upadhayay, Sagar [Radiation Oncology, Kathmandu Cancer Center, Bhaktapur (Nepal); Das, K. J. Maria [Dept. of Radiotherapy, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Uttar Pradesh (India)

    2017-03-15

    To Study the dosimetric advantage of the Jaw tracking technique in intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) for Head and Neck Cancers. We retrospectively selected 10 previously treated head and neck cancer patients stage (T1/T2, N1, M0) in this study. All the patients were planned for IMRT and VMAT with simultaneous integrated boost technique. IMRT and VMAT plans were performed with jaw tracking (JT) and with static jaw (SJ) technique by keeping the same constraints and priorities for a particular patient. Target conformity, dose to the critical structures and low dose volumes were recorded and analyzed for IMRT and VMAT plans with and without JT for all the patients. The conformity index average of all patients followed by standard deviation (x¯x¯ ± σx¯σx¯) of the JT-IMRT, SJ-IMRT, JT-VMAT, and SJ-VMAT were 1.72 ± 0.56, 1.67 ± 0.57, 1.83 ± 0.65, and 1.85 ± 0.64, and homogeneity index were 0.059 ± 0.05, 0.064 ± 0.05, 0.064 ± 0.04, and 0.064 ± 0.05. JT-IMRT shows significant mean reduction in right parotid and left parotid shows of 7.64% (p < 0.001) and 7.45% (p < 0.001) compare to SJ-IMRT. JT-IMRT plans also shows considerable dose reduction to thyroid, inferior constrictors, spinal cord and brainstem compared to the SJ-IMRT plans. Significant dose reductions were observed for critical structure in the JT-IMRT compared to SJ-IMRT technique. In JT-VMAT plans dose reduction to the critical structure were not significant compared to the SJ-IMRT due to relatively lesser monitor units.

  14. Strontium ranelate treatment in a postmenopausal woman with osteonecrosis of the jaw after long-term oral bisphosphonate administration: a case report.

    Science.gov (United States)

    Pan, Whei-Lin; Chen, Pi-Lun; Lin, Cho-Ying; Pan, Yi-Chun; Ju, Yuh-Ren; Chan, Chiu-Po; Hsu, Robert Ww

    2017-01-01

    Bisphosphonates (BPs) suppress bone resorption and increase bone strength, thus reducing the risk of fracture. Oral BPs are widely used for the prevention and treatment of osteoporosis and osteopenia. Here, we describe the case of a postmenopausal woman who took oral alendronate for >3 years for osteoporosis. The patient presented at the clinic with sharp jaw pain and swelling on the left mandible 4 months after extraction of the third molar. Clinical examinations identified an inflamed mucosal opening with pus over an area of necrotic bone. Initial images of cone beam computed tomography revealed a sequestrum at the extracted socket. The condition did not improve after 1 week of antibiotic treatment; therefore, the alendronate treatment was terminated and the patient was prescribed strontium ranelate instead. The patient gradually recovered and, at the 2-year follow-up, the site of BP-related osteonecrosis of the jaw healed completely as determined by both clinical and cone beam computed tomography measures. The bone mineral densities in the femoral neck and lumbar spine improved after 1 year, and were maintained at the 3-year follow-up. The serum C-terminal cross-linking telopeptide values also gradually increased from the initial 130 pg/mL to 320 pg/mL at the 3-year follow-up. Taken together, this case supports the use of strontium ranelate as an alternative treatment for postmenopausal women who receive long-term oral BP treatments and are at risk for serious complications of BP-related osteonecrosis of the jaw.

  15. Left Ventricular Assist Devices

    Directory of Open Access Journals (Sweden)

    Khuansiri Narajeenron

    2017-04-01

    Full Text Available Audience: The audience for this classic team-based learning (cTBL session is emergency medicine residents, faculty, and students; although this topic is applicable to internal medicine and family medicine residents. Introduction: A left ventricular assist device (LVAD is a mechanical circulatory support device that can be placed in critically-ill patients who have poor left ventricular function. After LVAD implantation, patients have improved quality of life.1 The number of LVAD patients worldwide continues to rise. Left-ventricular assist device patients may present to the emergency department (ED with severe, life-threatening conditions. It is essential that emergency physicians have a good understanding of LVADs and their complications. Objectives: Upon completion of this cTBL module, the learner will be able to: 1 Properly assess LVAD patients’ circulatory status; 2 appropriately resuscitate LVAD patients; 3 identify common LVAD complications; 4 evaluate and appropriately manage patients with LVAD malfunctions. Method: The method for this didactic session is cTBL.

  16. Higher operation temperature quadrant photon detectors of 2-11 μm wavelength radiation with large photosensitive areas

    Science.gov (United States)

    Pawluczyk, J.; Sosna, A.; Wojnowski, D.; Koźniewski, A.; Romanis, M.; Gawron, W.; Piotrowski, J.

    2017-10-01

    We report on the quadrant photon HgCdTe detectors optimized for 2-11 μm wavelength spectral range and Peltier or no cooling, and photosensitive area of a quad-cell of 1×1 to 4×4 mm. The devices are fabricated as photoconductors or multiple photovoltaic cells connected in series (PVM). The former are characterized by a relatively uniform photosensitive area. The PVM photovoltaic cells are distributed along the wafer surface, comprising a periodical stripe structure with a period of 20 μm. Within each period, there is an insensitive gap/trench 1.4×108 cm×Hz1/2/W for photoconductor and >1.7×108 cm·Hz1/2/W for PVM, allowing for position control of the radiation beam with submicron accuracy at 16 MHz, 10.6 μm wavelength of pulsed radiation spot of 0.8 mm dia at the close-to-maximal input radiation power density in a range of detector linear operation.

  17. Four-quadrant silicon and silicon carbide photodiodes for beam position monitor applications: electrical characterization and electron irradiation effects

    Science.gov (United States)

    Rafí, J. M.; Pellegrini, G.; Godignon, P.; Quirion, D.; Hidalgo, S.; Matilla, O.; Fontserè, A.; Molas, B.; Takakura, K.; Tsunoda, I.; Yoneoka, M.; Pothin, D.; Fajardo, P.

    2018-01-01

    Silicon photodiodes are very useful devices as X-ray beam monitors in synchrotron radiation beamlines, as well as other astronomy and space applications. Owing to their lower susceptibility to variable temperature and illumination conditions, there is also special interest in silicon carbide devices for some of these applications. Moreover, radiation hardness of the involved technologies is a major concern for high-energy physics and space applications. This work presents four-quadrant photodiodes produced on ultrathin (10 μm) and bulk Si, as well as on SiC epilayer substrates. An extensive electrical characterization has been carried out by using current-voltage (I-V) and capacitance-voltage (C-V) techniques. The impact of different temperature (from ‑50oC to 175oC) and visible light conditions on the electrical characteristics of the devices has been evaluated. Radiation effects caused by 2 MeV electron irradiation up to 1×1014, 1×1015 and 1×1016 e/cm2 fluences have been studied. Special attention has been devoted to the study of charge build-up in diode interquadrant isolation, as well as its impact on interquadrant resistance. The study of these electrical properties and its radiation-induced degradation should be taken into account for device applications.

  18. A new technique for the diagnosis of acute appendicitis: abdominal CT with compression to the right lower quadrant

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    Kilincer, Abidin; Akpinar, Erhan; Uenal, Emre; Karaosmanoglu, Ali Devrim; Akata, Deniz; Oezmen, Mustafa [Hacettepe University Faculty of Medicine, Department of Radiology, Sihhiye, Ankara (Turkey); Erbil, Buelent [Hacettepe University Faculty of Medicine, Department of Emergency Medicine, Ankara (Turkey); Kaynaroglu, Volkan [Hacettepe University Faculty of Medicine, Department of General Surgery, Ankara (Turkey)

    2017-08-15

    To determine the diagnostic accuracy of abdominal CT with compression to the right lower quadrant (RLQ) in adults with acute appendicitis. 168 patients (age range, 18-78 years) were included who underwent contrast-enhanced CT for suspected appendicitis performed either using compression to the RLQ (n = 71) or a standard protocol (n = 97). Outer diameter of the appendix, appendiceal wall thickening, luminal content and associated findings were evaluated in each patient. Kruskal-Wallis, Fisher's and Pearson's chi-squared tests were used for statistical analysis. There was no significant difference in the mean outer diameter (MOD) between compression CT scans (10.6 ± 1.9 mm) and standard protocol (11.2 ± 2.3 mm) in patients with acute appendicitis (P = 1). MOD was significantly lower in the compression group (5.2 ± 0.8 mm) compared to the standard protocol (6.5 ± 1.1 mm) (P < 0.01) in patients without appendicitis. A cut-off value of 6.75 mm for the outer diameter of the appendix was found to be 100% sensitive in the diagnosis of acute appendicitis for both groups. The specificity was higher for compression CT technique (67.7 vs. 94.9%). Normal appendix diameter was significantly smaller in the compression-CT group compared to standard-CT group, increasing diagnostic accuracy of abdominal compression CT. (orig.)

  19. Left neglected, but only in far space: Spatial biases in healthy participants revealed in a visually-guided grasping task

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    Natalie ede Bruin

    2014-01-01

    Full Text Available Hemispatial neglect is a common outcome of stroke that is characterised by the inability to orient towards, and attend to stimuli in contralesional space. It is established that hemispatial neglect has a perceptual component, however, the presence and severity of motor impairments is controversial. Establishing the nature of space use and spatial biases during visually-guided actions amongst healthy individuals is critical to understanding the presence of visuomotor deficits in patients with neglect. Accordingly, three experiments were conducted to investigate the effect of object spatial location on patterns of grasping. Experiment 1 required right-handed participants to reach and grasp for blocks in order to construct 3D models. The blocks were scattered on a tabletop divided into equal size quadrants: left near, left far, right near, and right far. Identical sets of building blocks were available in each quadrant. Space use was dynamic, with participants initially grasping blocks from right near space and tending to ‘neglect’ left far space until the final stages of the task. Experiment 2 repeated the protocol with left-handed participants. Remarkably, left-handed participants displayed a similar pattern of space use to right-handed participants. In Experiment 3 eye movements were examined to investigate whether ‘neglect’ for grasping in left far reachable space had its origins in attentional biases. It was found that patterns of eye movements mirrored patterns of reach-to-grasp movements. We conclude that there are spatial biases during visually-guided grasping, specifically, a tendency to neglect left far reachable space, and that this ‘neglect’ is attentional in origin. The results raise the possibility that visuomotor impairments reported among patients with right hemisphere lesions when working in contralesional space may result in part from this inherent tendency to ‘neglect’ left far space irrespective of the presence

  20. Perspectives of the use of commissure in patients with oblique fractures of the lower jaw

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    Yuri Efimov

    2016-02-01

    Full Text Available There was carried out an analysis of the results of treatment of 34 patients with oblique fractures of the lower jaw by the method of commissure osteosynthesis that was elaborated by the authors.Aim: to increase the effectiveness of treatment of patients with oblique fractures of the lower jaw at the expense of optimization of commissure osteosynthesis.Methods: there was carried out examination and operative treatment of 34 patients with oblique fractures of lower jaw of the different localization. In the area of the lower jaw angle – 19 (55,88 % patients, in the area of the lower jaw body – 12 (35,29 % persons, the number of patients with fractures of the neck with dislocation of the head of lower jaw was 3 (8,83 %. All patients were the persons of male sex 32–55 years old. The operative treatment was consisted in commissure osteosynthesis according to the method elaborated by the authors.Results: there were not observed any complication in operated patients during postoperative period. There were not observed the secondary displacement of splinters or inflammatory complications. The consolidation of splinters was clinically observed on 21 day after operation. In remote terms (3 month after osteosynthesis patients have no complaints the disorders of dental occlusion did not take place.Conclusions: An offered method of osteosynthesis with wire suture allows:1. Eliminate the horizontal displacement of splinters;2. Eliminate the shortening of the jaw arch and the deviation of occlusion with deformation of the patient’s face;3. Raise the stability of osteosynthesis.The remote results testify the high effectiveness of the method that allows recommend it for the wide use in clinical practice

  1. Does evolutionary innovation in pharyngeal jaws lead to rapid lineage diversification in labrid fishes?

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    Wainwright Peter C

    2009-10-01

    Full Text Available Abstract Background Major modifications to the pharyngeal jaw apparatus are widely regarded as a recurring evolutionary key innovation that has enabled adaptive radiation in many species-rich clades of percomorph fishes. However one of the central predictions of this hypothesis, that the acquisition of a modified pharyngeal jaw apparatus will be positively correlated with explosive lineage diversification, has never been tested. We applied comparative methods to a new time-calibrated phylogeny of labrid fishes to test whether diversification rates shifted at two scales where major pharyngeal jaw innovations have evolved: across all of Labridae and within the subclade of parrotfishes. Results Diversification patterns within early labrids did not reflect rapid initial radiation. Much of modern labrid diversity stems from two recent rapid diversification events; one within julidine fishes and the other with the origin of the most species-rich clade of reef-associated parrotfishes. A secondary pharyngeal jaw innovation was correlated with rapid diversification within the parrotfishes. However diversification rate shifts within parrotfishes are more strongly correlated with the evolution of extreme dichromatism than with pharyngeal jaw modifications. Conclusion The temporal lag between pharyngeal jaw modifications and changes in diversification rates casts doubt on the key innovation hypothesis as a simple explanation for much of the richness seen in labrids and scarines. Although the possession of a secondarily modified PJA was correlated with increased diversification rates, this pattern is better explained by the evolution of extreme dichromatism (and other social and behavioral characters relating to sexual selection within Scarus and Chlorurus. The PJA-innovation hypothesis also fails to explain the most dominant aspect of labrid lineage diversification, the radiation of the julidines. We suggest that pharyngeal jaws might have played a more

  2. Disparities in Utilization of Jaw Surgery for Treatment of Sleep Apnea: A Nationwide Analysis.

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    Garg, Ravi K; Shan, Ying; Havlena, Jeffrey A; Afifi, Ahmed M

    2016-12-01

    Maxillomandibular advancement has been shown to be one of the most effective operations for management of severe obstructive sleep apnea, yet pharyngeal surgery is more commonly performed. The goal of this study was to identify socioeconomic factors associated with this phenomenon. Patients aged 14 or older with a primary hospital diagnosis of sleep apnea were identified using the National Inpatient Sample from 2005 to 2012. ICD9 codes were used to determine whether a pharyngeal or jaw procedure was performed. Patient demographics, comorbidities, and complications were compared. Among 6316 sleep surgeries, 5964 (94.4%) were pharyngeal and 352 (5.6%) were jaw procedures. Women were significantly more likely to receive jaw surgery than men (odds ratio [OR] = 1.68, P = 0.0007). African Americans (OR = 0.19, P < 0.0001), Hispanics (OR = 0.42, P = 0.0009), Asians (OR = 0.41, P = 0.0009), and other non-Caucasians (OR = 0.19, P = 0.0008) had a significantly lower odds of receiving jaw surgery than Caucasians. Patients falling into lower-income brackets (OR = 0.39 and 0.57, P = 0.02 and 0.04) and patients with Medicare compared with private or Health Maintenance Organization insurance (OR = 0.46, P = 0.008) also had significantly decreased odds of undergoing jaw surgery. Comorbidities were similar between surgical groups, and there were no significant differences in bleeding, infection, or cardiopulmonary complications. We identified no significant difference in complication rates between pharyngeal and jaw procedures. Nonetheless, African American, Hispanic, and Asian patients, in addition to lower-income patients and patients with Medicare, had a significantly lower odds of receiving jaw surgery. Awareness of these disparities may help guide efforts to improve patients' surgical options for sleep apnea.

  3. Effects of aging and sarcopenia on tongue pressure and jaw-opening force.

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    Machida, Nami; Tohara, Haruka; Hara, Koji; Kumakura, Ayano; Wakasugi, Yoko; Nakane, Ayako; Minakuchi, Shunsuke

    2017-02-01

    Aging and sarcopenia reduce not only body strength, but also the strength of swallowing muscles. We examined how aging and sarcopenia affect tongue pressure and jaw-opening force. A total of 97 older adults (97 men, mean age 78.5 ± 6.6 years; 100 women, mean age 77.8 ± 6.2 years) were enrolled. Classification of sarcopenia was based on the Criteria of Asian Working Group for Sarcopenia. To investigate which variable between aging and sarcopenia was a significant independent variable on tongue pressure and jaw-opening force, multivariate linear regression analysis was carried out. The mean tongue pressure was 26.3 ± 7.8 kPa in men and 24.6 ± 7.2 kPa in women. The mean jaw-opening force was 6.3 ± 1.6 kg in men and 5.2 ± 1.3 kg in women. Tongue pressure in men, aging and sarcopenia were significant independent variables, whereas only sarcopenia was a significant independent variable in women. Jaw-opening force in men and sarcopenia were significant independent variables, whereas neither aging nor sarcopenia were significant independent variables in women. We found different characteristics in the effects of aging and sarcopenia based on site and sex. We suggested that aging decreased tongue pressure more than jaw-opening force, and affected men more than women. Sarcopenia affected tongue pressure and jaw-opening force, with the exception of jaw-opening force in women. Considering these characteristics is useful to predict the decline of swallowing function, and provide appropriate interventions preventing dysphagia. Geriatr Gerontol Int 2017; 17: 295-301. © 2016 Japan Geriatrics Society.

  4. Jaw-muscle force and excursion scale with negative allometry in platyrrhine primates.

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    Taylor, Andrea B; Yuan, Tian; Ross, Callum F; Vinyard, Christopher J

    2015-07-14

    Platyrrhines span two orders of magnitude in body size and are characterized by diverse feeding behaviors and diets. While size plays an important role in primate feeding behavior and masticatory apparatus morphology, we know little about size-correlated changes in the force-generating (physiologic cross-sectional area; PCSA) and excursion/stretch (fiber length; L f ) capabilities of the jaw-closing muscles in platyrrhines. We examined scaling relationships of the superficial masseter and temporalis muscles in 21 platyrrhine species. Previous work suggests that larger platyrrhines are at a mechanical disadvantage for generating bite forces compared with smaller platyrrhines. We hypothesize that scaling of jaw-muscle fiber architecture counters this size-correlated decrease in mechanical advantage. Thus, we predicted that jaw-muscle PCSAs and muscle weights scale with positive allometry while L f s scale with negative allometry, relative to load-arm estimates for incisor/molar biting and chewing. Jaw-muscle PCSAs and L f s appear to scale with negative allometry relative to load-arm estimates and body size. Negative allometry of jaw-muscle weights partially accounts for the size-correlated decreases in PCSA and L f . Estimates of bite force also scale with negative allometry. Large-bodied platyrrhines (e.g., Alouatta) are at a relative disadvantage for generating jaw-muscle and bite force as well as jaw-muscle stretch, compared with smaller species (e.g., Callithrix). The net effect is that larger platyrrhines likely produce relatively smaller maximal bite forces compared with smaller taxa. Relative to small- and intermediate-sized platyrrhines, large-bodied platyrrhines feed on some of the least mechanically challenging foods, consistent with the size-correlated decrease in relative muscle and bite forces across the clade. Am J Phys Anthropol, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  5. Expression of Msx-1 is suppressed in bisphosphonate associated osteonecrosis related jaw tissue-etiopathology considerations respecting jaw developmental biology-related unique features

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    Schlegel Karl A

    2010-10-01

    Full Text Available Abstract Background Bone-destructive disease treatments include bisphosphonates and antibodies against the osteoclast differentiator, RANKL (aRANKL; however, osteonecrosis of the jaw (ONJ is a frequent side-effect. Current models fail to explain the restriction of bisphosphonate (BP-related and denosumab (anti-RANKL antibody-related ONJ to jaws. Msx-1 is exclusively expressed in craniofacial structures and pivotal to cranial neural crest (CNC-derived periodontal tissue remodeling. We hypothesised that Msx-1 expression might be impaired in bisphosphonate-related ONJ. The study aim was to elucidate Msx-1 and RANKL-associated signal transduction (BMP-2/4, RANKL in ONJ-altered and healthy periodontal tissue. Methods Twenty ONJ and twenty non-BP exposed periodontal samples were processed for RT-PCR and immunohistochemistry. An automated staining-based alkaline phosphatase-anti-alkaline phosphatase method was used to measure the stained cells:total cell-number ratio (labelling index, Bonferroni adjustment. Real-time RT-PCR was performed on ONJ-affected and healthy jaw periodontal samples (n = 20 each to quantitatively compare Msx-1, BMP-2, RANKL, and GAPDH mRNA levels. Results Semi-quantitative assessment of the ratio of stained cells showed decreased Msx-1 and RANKL and increased BMP-2/4 (all p Conclusions These results explain the sclerotic and osteopetrotic changes of periodontal tissue following BP application and substantiate clinical findings of BP-related impaired remodeling specific to periodontal tissue. RANKL suppression substantiated the clinical finding of impaired bone remodelling in BP- and aRANKL-induced ONJ-affected bone structures. Msx-1 suppression in ONJ-adjacent periodontal tissue suggested a bisphosphonate-related impairment in cellular differentiation that occurred exclusively jaw remodelling. Further research on developmental biology-related unique features of jaw bone structures will help to elucidate pathologies restricted to

  6. [Difficulties in face identification after lesion in the left hemisphere].

    Science.gov (United States)

    Verstichel, P; Chia, L

    1999-11-01

    A 82 year-old right-handed man, without any intellectual impairment, suffered from an acute neurological deficit consisting in letter-by-letter reading, right superior quadrant hemianopia with achromatopia in the lower quadrant, and anomia. Cerebral MRI showed an infarct involving the ventral structures of the left hemisphere sparing the splenium of the corpus callosum and the thalamus. Neuropsychological examination revealed that the patient easily identified the objects, the animals and the famous places he could not name: his comments attested normal visual recognition. Conversely, when he was presented with famous faces, he always had a strong feeling of familiarity, but could not provide accurate information about the corresponding individual. Biographic information about personalities was not impaired in the semantic-biographic store, because it could be accessed from the names. Activation of face recognition units (where the visual description provided by the structural encoding and the stored sets of descriptions of familiar faces are compared), was effective, since the patient could distinguish famous faces from unknown ones. In a modular-sequential model of face recognition, this deficit is interpreted as a disconnection between face recognition units and person identity nodes (which are considered to contain semantic-biographic information about individuals). This kind of disturbance differs from classic prosopagnosia in which, characteristically, the patients are unable to experience a feeling of familiarity when viewing famous faces, and to perform a categorization between famous and unknown faces. Right hemisphere has a preponderant role in structural analysis of faces and in activation of face recognition units. The integrity of this hemisphere in this patient could explain the preservation of these two steps of processing. Left-hemisphere specific function in facial recognition enabled access to semantic-biographic store in a conscious, verbal and

  7. Influence of the Lower Jaw Position on the Running Pattern.

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    Christian Maurer

    Full Text Available The effects of manipulated dental occlusion on body posture has been investigated quite often and discussed controversially in the literature. Far less attention has been paid to the influence of dental occlusion position on human movement. If human movement was analysed, it was mostly while walking and not while running. This study was therefore designed to identify the effect of lower jaw positions on running behaviour according to different dental occlusion positions.Twenty healthy young recreational runners (mean age = 33.9±5.8 years participated in this study. Kinematic data were collected using an eight-camera Vicon motion capture system (VICON Motion Systems, Oxford, UK. Subjects were consecutively prepared with four different dental occlusion conditions in random order and performed five running trials per test condition on a level walkway with their preferred running shoes. Vector based pattern recognition methods, in particular cluster analysis and support vector machines (SVM were used for movement pattern identification.Subjects exhibited unique movement patterns leading to 18 clusters for the 20 subjects. No overall classification of the splint condition could be observed. Within individual subjects different running patterns could be identified for the four splint conditions. The splint conditions lead to a more symmetrical running pattern than the control condition.The influence of an occlusal splint on running pattern can be confirmed in this study. Wearing a splint increases the symmetry of the running pattern. A more symmetrical running pattern might help to reduce the risk of injuries or help in performance. The change of the movement pattern between the neutral condition and any of the three splint conditions was significant within subjects but not across subjects. Therefore the dental splint has a measureable influence on the running pattern of subjects, however subjects individuality has to be considered when choosing the

  8. Implementation and commissioning of an integrated micro-CT/RT system with computerized independent jaw collimation

    International Nuclear Information System (INIS)

    Jensen, Michael D.; Hrinivich, W. Thomas; Jung, Jongho A.; Holdsworth, David W.; Drangova, Maria; Chen, Jeff; Wong, Eugene

    2013-01-01

    Purpose: To design, construct, and commission a set of computer-controlled motorized jaws for a micro-CT/RT system to perform conformal image-guided small animal radiotherapy.Methods: The authors designed and evaluated a system of custom-built motorized orthogonal jaws, which allows the delivery of off-axis rectangular fields on a GE eXplore CT 120 preclinical imaging system. The jaws in the x direction are independently driven, while the y-direction jaws are symmetric. All motors have backup encoders, verifying jaw positions. Mechanical performance of the jaws was characterized. Square beam profiles ranging from 2 × 2 to 60 × 60 mm 2 were measured using EBT2 film in the center of a 70 × 70 × 22 mm 3 solid water block. Similarly, absolute depth dose was measured in a solid water and EBT2 film stack 50 × 50 × 50 mm 3 . A calibrated Farmer ion chamber in a 70 × 70 × 20 mm 3 solid water block was used to measure the output of three field sizes: 50 × 50, 40 × 40, and 30 × 30 mm 2 . Elliptical target plans were delivered to films to assess overall system performance. Respiratory-gated treatment was implemented on the system and initially proved using a simple sinusoidal motion phantom. All films were scanned on a flatbed scanner (Epson 1000XL) and converted to dose using a fitted calibration curve. A Monte Carlo beam model of the micro-CT with the jaws has been created using BEAMnrc for comparison with the measurements. An example image-guided partial lung irradiation in a rat is demonstrated.Results: The averaged random error of positioning each jaw is less than 0.1 mm. Relative output factors measured with the ion chamber agree with Monte Carlo simulations within 2%. Beam profiles and absolute depth dose curves measured from the films agree with simulations within measurement uncertainty. Respiratory-gated treatments applied to a phantom moving with a peak-to-peak amplitude of 5 mm showed improved beam penumbra (80%–20%) from 3.9 to 0.8 mm.Conclusions: A

  9. Left Ventricular Pseudoaneurysm Perceived as a Left Lung Mass

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    Ugur Gocen

    2013-02-01

    Full Text Available Left ventricular pseudo-aneurysm is a rare complication of aneurysmectomy. We present a case of surgically-treated left ventricular pseudo-aneurysm which was diagnosed three years after coronary artery bypass grafting and left ventricular aneurysmectomy. The presenting symptoms, diagnostic evaluation and surgical repair are described. [Cukurova Med J 2013; 38(1.000: 123-125

  10. Lesions of the jaws presenting as radiolucencies on cone-beam CT.

    Science.gov (United States)

    MacDonald, D

    2016-10-01

    In order to compliment the current interest in lesions affecting the face and jaws in Clinical Radiology, this overview addresses recent developments in the classification, nomenclature, clinical and radiological diagnosis, and outcomes of treatment of the most important and frequent lesions that present as radiolucencies on conventional radiography of the jaws. Although termed "benign" a significant proportion of each odontogenic neoplasm can recur after conservative surgery. Two diagnostic flowcharts take the clinician from the radiological presentation of a lesion in the jaw to an appropriate diagnosis. The recent advent of cone-beam computed tomography (CBCT) can enhance the quality of the diagnosis and preoperative assessment of such lesions. CBCT images of typical benign neoplasms, cysts, and other phenomena affecting the face and jaws are included. The relative period prevalences of the lesions, based on the most recent UK reports, are included. The importance to the radiologist of an emerging lesion of the jaws, the glandular odontogenic cyst, is discussed. Copyright © 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  11. A CLINICOPATHOLOGICAL STUDY OF JAW LESIONS AT A TERTIARY CARE CENTRE

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    Naval Kishore Bajaj

    2016-08-01

    Full Text Available BACKGROUND Jaw bones are exceptional developmentally in having embryonal neuroectodermal cells on one hand and tooth germs on other. They cause destruction of the jaw bones and pose diagnostic challenge. MATERIAL AND METHODS Patients attending Oral and Maxillofacial Surgery Department at Osmania General Hospital during the period January 2013- May 2016 presenting with complaints of gradually progressive of jaw swelling, toothache and with radiological evaluation showing osteolytic, sclerotic, and cystic change were subjected to surgical excision. Representative tissue samples were processed routinely and stained by haematoxylin and eosin. RESULTS A total of 55 cases of lesions involving jaw bones were studied out of which 21 cases occurred in females and 34 cases in males. 47 lesions were encountered in mandible and 7 lesions in maxilla. A single case of firm-to-hard submandibular swelling was also included in the study. The lesions were categorised into cysts, odontogenic tumours, reactive bone lesions, giant cell lesions, and primary bone tumours. Ameloblastoma was the most common odontogenic tumour type, 15/55; one ameloblastoma case was recurrent followed by radicular cyst 7/55 and dentigerous cyst accounting for six cases and variety of other lesions. CONCLUSION A whole gamut of lesions occurred in the jaws presented with a considerable overlap in clinical, histological, and radiological features. The present study revealed mostly cystic and benign neoplastic lesions.

  12. Osteonecrosis of the Jaw in Patients Receiving Bone-Targeted Therapies: An Overview--Part I.

    Science.gov (United States)

    Turner, Bruce; Drudge-Coates, Lawrence; Ali, Sacha; Pati, Jhumur; Nargund, Vinod; Ali, Enamul; Cheng, Leo; Wells, Paula

    2016-01-01

    Urologic patients receiving bone-targeted therapies are at risk of developing osteonecrosis of the jaw (ONJ). ONJ has historically been associated with bisphosphonate therapy. More recently, RANK-Ligand inhibitors (denosumab) have also been used to reduce the risk of skeletal-related events in patients who have advanced cancers with bone metastases. More than 65% of men with metastatic prostate cancer and nearly 75% of women with metastatic breast cancer are affected by bone metastases. The literature has described ONJ associated with bisphosphonate therapy as bisphosphonate-related osteonecrosis of the jaw (BRONJ). However, with evidence also linking the use of RANK-Ligand inhibitors with osteonecrosis of the jaw, we advocate use of the term "anti-bone resorption therapy-related osteonecrosis of the jaw" (ABRT-ONJ). The term "medication-related osteonecrosis of the jaw" (MRONJ) is now becoming more widespread. There is not a universally accepted definition of ABRT-ONJ, which may have hindered recognition and reporting of the condition. In Part I of this article, a review of current knowledge around the etiology of ABRT-ONJ and incidence data are provided. In Part II, we provide an audit of ONJ in a nurse consultant-led bone support clinic. In the article, we refer to zoledronic acid because this is the bisphosphonate of choice for use in men with prostate cancer in the United Kingdom.

  13. Kinematic and diffusion tensor imaging definition of familial Marcus Gunn jaw-winking synkinesis.

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    Antonella Conte

    Full Text Available BACKGROUND: Marcus Gunn jaw-winking synkinesis (MGJWS is characterized by eyelid ptosis, which disappears during jaw movement. Familial MGJWS is an extremely rare condition. Some authors suggested that MGJWS is due to neural misdirection in the brainstem whereas others suggested that aberrant reinnervation or ephapse may be responsible for synkinetic activity. Pathogenesis of this condition is therefore still unclear. METHODOLOGY/PRINCIPAL FINDINGS: To investigate pathogenetic mechanism in familial MGJWS we performed neurophysiological (EMG, Blink Reflex, Recovery cycle of the R2 component of the blink reflex, Masseter inhibitory reflex, BAEPS and kinematic analysis and neuroradiological (MRI, Diffusion Tensor Imaging investigations in a member of a multigenerational family with autosomal dominant Marcus Gunn jaw-winking synkinesis (MGJWS. Kinematic analysis of eyelid and jaw movements disclosed a similar onset and offset of the eyelid and jaw in both the opening and closing phases. The excitability of brainstem circuits, as assessed by the blink reflex recovery cycle and recovery index, was normal. Diffusion Tensor Imaging revealed reduced fractional anisotropy within the midbrain tegmentum. CONCLUSIONS/SIGNIFICANCE: Kinematic and MRI findings point to a brainstem structural abnormality in our familial MGJWS patient thus supporting the hypothesis of a neural misdirection of trigeminal motor axons to the elevator palpebralis muscle.

  14. The oral microbial community of gingivitis and lumpy jaw in captive macropods.

    Science.gov (United States)

    Antiabong, John F; Boardman, Wayne; Moore, Robert B; Brown, Melissa H; Ball, Andrew S

    2013-12-01

    Gingivitis and lumpy jaw are diseases of polymicrobial aetiology. Although Fusobacterium necrophorum has been associated with these diseases in macropods, little is known about other organisms associated with these diseases in this animal species. PCR-DGGE analysis revealed the potential pathogens associated with gingivitis and lumpy jaw in macropods. PCR-DGGE profile comparison between the healthy and disease groups indicated a shift in the oral bacterial community structures with similarity coefficients of 48% and 35% for gingivitis and lumpy jaw respectively. Moreover, gingivitis was associated with increase in bacterial diversity (Shannon index = 2.87; PL curve = 45%) while lumpy jaw resulted in a decline in bacterial diversity (Shannon index = 2.47; PL curve = 74%). This study suggest that the establishment of gingivitis and lumpy jaw diseases follows the ecological plaque hypothesis. This forms the basis for an expanded investigation in an epidemiological scale and suggests the need for the appropriate choice of antimicrobial agent(s) and for the effective management and control of polymicrobial diseases. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Radiographic features of large cystic lesions of the jaws in children.

    Science.gov (United States)

    Bodner, Lipa; Woldenberg, Yitzhak; Bar-Ziv, Jacob

    2003-01-01

    The surgical approach to cystic lesions of the jaws is either marsupialisation or enucleation. The treatment of choice is dependent on the size of the lesion, the bony integrity of the cyst and its proximity to anatomical structures. To assess large (>2.0 cm) cystic lesions of the jaws using plain film radiography (PFR), CT, multiplanar reconstruction program (MPR) and three-dimensional CT (3D-CT). Twelve children aged 7-14 years. The classic radiological feature was a unilocular radiolucent area surrounded by a well-defined radio-opaque margin adjacent to the root of a non-viable tooth or associated with the crown of an unerupted tooth. Malposition of teeth and root resorption were more common in dentigerous cysts. The features seen on CT were clear and more precise than those seen on PFR. MPR, by the three-dimensional visualisation of the jaw (axial, panoramic, and bucco-lingual), provided useful information for determining the outline of the cyst and its proximity to adjacent anatomical structures, such as teeth, nerves or maxillary sinus. 3-D CT further and more clearly demonstrated discontinuity in the buccal or palatal/lingual cortices of the jaw bone. PFR was very accurate in determining root resorption. CT with MPR and, ideally, 3-D CT should be used for the comprehensive diagnostic work-up and meticulous surgical management of large cystic lesions of the jaws in children.

  16. Radiographic features of large cystic lesions of the jaws in children

    Energy Technology Data Exchange (ETDEWEB)

    Bodner, Lipa; Woldenberg, Yitzhak [Department of Oral and Maxillofacial Surgery, Soroka Medical Center, P.O. Box 151, Beer-Sheva 84101 (Israel); Bar-Ziv, Jacob [Department of Radiology, Hebrew University and Hadassab School of Medicine, Jerusalem (Israel)

    2003-01-01

    The surgical approach to cystic lesions of the jaws is either marsupialisation or enucleation. The treatment of choice is dependent on the size of the lesion, the bony integrity of the cyst and its proximity to anatomical structures.Objectives. To assess large (>2.0 cm) cystic lesions of the jaws using plain film radiography (PFR), CT, multiplanar reconstruction program (MPR) and three-dimensional CT (3D-CT).Patients and methods. Twelve children aged 7-14 years.Results. The classic radiological feature was a unilocular radiolucent area surrounded by a well-defined radio-opaque margin adjacent to the root of a non-viable tooth or associated with the crown of an unerupted tooth. Malposition of teeth and root resorption were more common in dentigerous cysts. The features seen on CT were clear and more precise than those seen on PFR. MPR, by the three-dimensional visualisation of the jaw (axial, panoramic, and bucco-lingual), provided useful information for determining the outline of the cyst and its proximity to adjacent anatomical structures, such as teeth, nerves or maxillary sinus. 3-D CT further and more clearly demonstrated discontinuity in the buccal or palatal/lingual cortices of the jaw bone. PFR was very accurate in determining root resorption.Conclusions. CT with MPR and, ideally, 3-D CT should be used for the comprehensive diagnostic work-up and meticulous surgical management of large cystic lesions of the jaws in children. (orig.)

  17. Strontium ranelate treatment in a postmenopausal woman with osteonecrosis of the jaw after long-term oral bisphosphonate administration: a case report

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    Pan WL

    2017-07-01

    Full Text Available Whei-Lin Pan,1,2 Pi-Lun Chen,2 Cho-Ying Lin,1,2 Yi-Chun Pan,2 Yuh-Ren Ju,1,2 Chiu-Po Chan,1,2 Robert WW Hsu2,3 1Department of Periodontics, Chang Gung Memorial Hospital, Taipei, Taiwan; 2Graduate Institute of Dental and Craniofacial Science, Chang Gung University, Taoyuan, Taiwan; 3Department of Orthopedics, Chang Gung Memorial Hospital, Taipei, Taiwan Abstract: Bisphosphonates (BPs suppress bone resorption and increase bone strength, thus reducing the risk of fracture. Oral BPs are widely used for the prevention and treatment of osteoporosis and osteopenia. Here, we describe the case of a postmenopausal woman who took oral alendronate for >3 years for osteoporosis. The patient presented at the clinic with sharp jaw pain and swelling on the left mandible 4 months after extraction of the third molar. Clinical examinations identified an inflamed mucosal opening with pus over an area of necrotic bone. Initial images of cone beam computed tomography revealed a sequestrum at the extracted socket. The condition did not improve after 1 week of antibiotic treatment; therefore, the alendronate treatment was terminated and the patient was prescribed strontium ranelate instead. The patient gradually recovered and, at the 2-year follow-up, the site of BP-related osteonecrosis of the jaw healed completely as determined by both clinical and cone beam computed tomography measures. The bone mineral densities in the femoral neck and lumbar spine improved after 1 year, and were maintained at the 3-year follow-up. The serum C-terminal cross-linking telopeptide values also gradually increased from the initial 130 pg/mL to 320 pg/mL at the 3-year follow-up. Taken together, this case supports the use of strontium ranelate as an alternative treatment for postmenopausal women who receive long-term oral BP treatments and are at risk for serious complications of BP-related osteonecrosis of the jaw. Keywords: bisphosphonate-related osteonecrosis of the jaw, BRONJ

  18. A new technique for the diagnosis of acute appendicitis: abdominal CT with compression to the right lower quadrant.

    Science.gov (United States)

    Kılınçer, Abidin; Akpınar, Erhan; Erbil, Bülent; Ünal, Emre; Karaosmanoğlu, Ali Devrim; Kaynaroğlu, Volkan; Akata, Deniz; Özmen, Mustafa

    2017-08-01

    To determine the diagnostic accuracy of abdominal CT with compression to the right lower quadrant (RLQ) in adults with acute appendicitis. 168 patients (age range, 18-78 years) were included who underwent contrast-enhanced CT for suspected appendicitis performed either using compression to the RLQ (n = 71) or a standard protocol (n = 97). Outer diameter of the appendix, appendiceal wall thickening, luminal content and associated findings were evaluated in each patient. Kruskal-Wallis, Fisher's and Pearson's chi-squared tests were used for statistical analysis. There was no significant difference in the mean outer diameter (MOD) between compression CT scans (10.6 ± 1.9 mm) and standard protocol (11.2 ± 2.3 mm) in patients with acute appendicitis (P = 1). MOD was significantly lower in the compression group (5.2 ± 0.8 mm) compared to the standard protocol (6.5 ± 1.1 mm) (P appendicitis. A cut-off value of 6.75 mm for the outer diameter of the appendix was found to be 100% sensitive in the diagnosis of acute appendicitis for both groups. The specificity was higher for compression CT technique (67.7 vs. 94.9%). Normal appendix diameter was significantly smaller in the compression-CT group compared to standard-CT group, increasing diagnostic accuracy of abdominal compression CT. • Normal appendix diameter is significantly smaller in compression CT. • Compression could force contrast material to flow through the appendiceal lumen. • Compression CT may be a CT counterpart of graded compression US.

  19. Usefulness of computed tomography in patients with right inferior abdominal quadrant pain: acute appendicitis and its alternative diagnosis

    International Nuclear Information System (INIS)

    Rossini, Sebastian A.; Haberman, Diego; Gonzalez Villaveiran, Ruben F.

    2009-01-01

    Purpose: To review the tomography findings of the acute appendicitis, their complications and alternative diagnosis. To value the use of helicoidal computed tomography (HCT) in the diagnosis of acute appendicitis and in the study of patients with right inferior abdominal quadrant (RIQ) pain and acute abdomen, for diagnosis and eventual complications, in order to decide treatment. Materials and method: For five months, the populations included in this retrospectively study were all patients delivered for presenting with RIQ pain for a HCT exam. These exams were made with oral and intravenous contrasts, when there were not contraindications. The HCT results were correlated with clinical follow up, surgery and histopathologic exams. Results: Over a total of 100 patients studied, 53 presented tomographic diagnosis of appendicitis, 22 of which presented perforation signs; 27 showed an alternative diagnosis (ovaries follicles, ureteral litiasis, tiphlitis, diverticulitis, colitis, salpingitis), 18 patients did not present tomographic findings to support the clinical symptoms and 2 presented indeterminated results. These data represented a sensibility of 100%, specificity of 95,7%, positive predictive value (PPV) of 96,2% and negative predictive value (NPV) of 100% for the tomography diagnosis of acute appendicitis and a sensibility of 100%, specificity of 81,8%, PPV of 95,1% and NPV of 100% for the tomography diagnosis of the different etiology in patient with right inferior acute abdomen. Conclusion: HCT is extremely useful in the study of patients with acute abdomen with origin in the RIQ, not only to make a diagnosis, but also to evaluate the complications, so as to decide proper treatment. (authors) [es

  20. Diagnosis of Upper Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of the American Physical Therapy Association.

    Science.gov (United States)

    Levenhagen, Kimberly; Davies, Claire; Perdomo, Marisa; Ryans, Kathryn; Gilchrist, Laura

    2017-07-01

    The Oncology Section of the American Physical Therapy Association (APTA) developed a clinical practice guideline to aid the clinician in diagnosing secondary upper quadrant cancer-related lymphedema. Following a systematic review of published studies and a structured appraisal process, recommendations were written to guide the physical therapist and other health care clinicians in the diagnostic process. Overall clinical practice recommendations were formulated based on the evidence for each diagnostic method and were assigned a grade based on the strength of the evidence for different patient presentations and clinical utility. In an effort to maximize clinical applicability, recommendations were based on the characteristics as to the location and stage of a patient's upper quadrant lymphedema. © American Physical Therapy Association 2017. Published by Oxford University Press [on behalf of the American Physical Therapy Association].

  1. Adenomatoid odontogenic tumor in jaw: case report and literature review

    International Nuclear Information System (INIS)

    Jalet Martinez, Antonio; Azofeifa Herrera, Jose P.

    2008-01-01

    Female patient of 15 years old is presented with an enlargement in the left mandibular parasymphyseal area. An orthopantomography was taken and a preliminary diagnosis of dentigerous cyst is suggested. The lesion is resected and sample is sent to the pathology laboratory. A diagnosis of adenomatoid odontogenic tumor is determined histopathologically. A literature review is conducted recently about that type of tumor. The importance of histological analysis of biopsies is highlighted. (author) [es

  2. Diagnosis of Upper Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of the American Physical Therapy Association

    OpenAIRE

    Levenhagen, Kimberly; Davies, Claire; Perdomo, Marisa; Ryans, Kathryn; Gilchrist, Laura

    2017-01-01

    Abstract The Oncology Section of the American Physical Therapy Association (APTA) developed a clinical practice guideline to aid the clinician in diagnosing secondary upper quadrant cancer-related lymphedema. Following a systematic review of published studies and a structured appraisal process, recommendations were written to guide the physical therapist and other health care clinicians in the diagnostic process. Overall clinical practice recommendations were formulated based on the evidence ...

  3. A Management Strategy for Idiopathic Bone Cavities of the Jaws.

    Science.gov (United States)

    Resnick, Cory M; Dentino, Kelley M; Garza, Ricardo; Padwa, Bonnie L

    2016-06-01

    Idiopathic bone cavities (IBCs) are benign osseous pseudocysts of unclear etiology. Their clinical course and response to treatment are poorly understood. The purpose of this study was to present a case series of patients with IBC with long-term follow-up. A retrospective case series of patients with IBC of the jaw was implemented. Medical records were reviewed for data on presentation and imaging. All patients underwent surgical exploration to confirm the diagnosis. Follow-up radiographs were evaluated for resolution or persistence after the procedure. Descriptive data were summarized. The sample included 45 patients (60% girls) with 47 IBCs who presented at a mean age of 13.5 ± 0.35 years (range, 9 to 17 yr). All lesions were asymptomatic and discovered as incidental findings; the average size was 2.0 cm (range, 0.8 to 7 cm). Most (n = 44) were solitary lesions of the mandible presenting within the body (n = 27), symphysis (n = 15), or ramus (n = 2). One patient had synchronous bilateral mandibular and maxillary IBCs. Common radiographic features included scalloping without root resorption or displacement and cortical thinning without expansion or perforation. Intraoperative findings showed an empty bone cavity often filled with blood-tinged serous fluid or blood. The histopathology of scrapings from the bony wall showed benign mixed fibrous tissue and no epithelial lining. Average radiographic follow-up was 32.7 ± 6.7 months (range, 0 to 9 yr). After exploration and curettage, 43% of patients had complete bone fill within 2 to 5 years. The other 57% had no change in lesion size at an average of 2.25 years (range, 2 to 9 yr). No patients developed symptoms, had enlargement of the lesion, or had pathologic fracture. Many IBCs persist for years despite exploration and curettage. Nonetheless, unresolved lesions did not enlarge or cause harm. A single procedure to confirm the diagnosis is sufficient for management. Copyright © 2016 The American

  4. Remote Estimation of Collimator Jaw Damages With Sounds Measurements During Beam Impacts

    CERN Document Server

    Deboy, D; Aberle, O; Carra, F; Cauchi, M; Lendaro, J; Masi, A; Redaelli, S

    2013-01-01

    Irregular hits of high-intensity LHC beams on collimators can lead to severe damage of the collimator jaws. The identification of damaged collimator jaws by observation of beam measurements is challenging: online loss measurements at the moment of the impacts can be tricky and degradation of the overall performance from single collimator damage can be difficult to measure. Visual inspections are excluded because collimator jaws are enclosed in vacuum tanks without windows. However, the sound generated during the beam impact can be used to give an estimate of the damage level. In 2012, high-intensity beam comparable to a full nominal LHC bunch at 7 TeV was shot on a tertiary type LHC collimator at the HiRadMat test facility at CERN. The paper presents results from sound recordings of this experiment.

  5. JAWS: Just Add Water System - A device for detection of nucleic acids in Martian ice caps

    DEFF Research Database (Denmark)

    Hansen, Anders J.; Willerslev, Eske; Mørk, Søren

    2002-01-01

    with a regulation of pH and salt concentrations e.g. the MOD systems and could be installed on a planetary probe melting its way down the Martian ice caps e.g. the NASA Cryobot. JAWS can be used for detection of remains of ancient life preserved in the Martian ice as well as for detection of contamination brought......The design of a device for nucleic acid detection in the Martian ice caps is presented; the Just Add Water System (JAWS). It is based on fiber-optic PNA (peptide nucleic acid) light up probe random microsphere universal array technology. JAWS is designed to be part of a larger system...

  6. Dental CT: imaging technique, anatomy, and pathologic conditions of the jaws

    International Nuclear Information System (INIS)

    Gahleitner, Andre; Watzek, G.; Imhof, H.

    2003-01-01

    In addition to conventional imaging methods, dental CT has become an established method for anatomic imaging of the jaws prior to dental implant placement. More recently, this high-resolution imaging technique has gained importance in diagnosing dental-associated diseases of the mandible and maxilla. Since most radiologists have had little experience in these areas, many of the CT findings remain undescribed. The objective of this review article is to present the technique of dental CT, to illustrate the typical appearance of jaw anatomy and dental-related diseases of the jaws with dental CT, and to show where it can serve as an addition to conventional imaging methods in dental radiology. (orig.)

  7. Bisphosphonate-related jaw necrosis--severe complication in maxillofacial surgery.

    Science.gov (United States)

    Eckert, A W; Maurer, P; Meyer, L; Kriwalsky, M S; Rohrberg, R; Schneider, D; Bilkenroth, U; Schubert, J

    2007-02-01

    Bisphosphonates are used as potent inhibitors in metastatic bone lesions. They can reduce skeletal burden and prevent bony metastases. They are integral in the treatment of some tumours like breast cancer, prostate cancer and multiple myeloma. As a side effect, these drugs also may cause severe jaw necrosis. Twenty-four patients with bisphosphonate-related jaw necrosis were analyzed in a clinical study. These necroses mostly appeared after administration of aminobisphosphonates. Recurrent avascular necroses were found after changing from Pramidronate to Zoledronate. All patients were treated by resection of necrotic bone. Repeated surgical interventions were required with about 25% of the patients. The management of patients with bisphosphonate-related jaw necrosis remains extremely difficult and includes surgical procedures as well as the eradicating of the necrotic bone including antibiotic therapy. The prevention of such complications consists in a minimization of dental surgical interventions and an avoidance of ulcers by dental prosthesis.

  8. Dental CT: imaging technique, anatomy, and pathologic conditions of the jaws

    Energy Technology Data Exchange (ETDEWEB)

    Gahleitner, Andre [Department of Radiology/Osteology, Medical School, University of Vienna, Waehringer Strasse 25a, 1090 Vienna (Austria); Department of Oral Surgery, Dental School, University of Vienna, Waehringer Strasse 25a, 1090 Vienna (Austria); Watzek, G. [Department of Oral Surgery, Dental School, University of Vienna, Waehringer Strasse 25a, 1090 Vienna (Austria); Imhof, H. [Department of Radiology/Osteology, Medical School, University of Vienna, Waehringer Strasse 25a, 1090 Vienna (Austria)

    2003-02-01

    In addition to conventional imaging methods, dental CT has become an established method for anatomic imaging of the jaws prior to dental implant placement. More recently, this high-resolution imaging technique has gained importance in diagnosing dental-associated diseases of the mandible and maxilla. Since most radiologists have had little experience in these areas, many of the CT findings remain undescribed. The objective of this review article is to present the technique of dental CT, to illustrate the typical appearance of jaw anatomy and dental-related diseases of the jaws with dental CT, and to show where it can serve as an addition to conventional imaging methods in dental radiology. (orig.)

  9. Effect of oral IQoro R and palatal plate training in post-stroke, four-quadrant facial dysfunction and dysphagia: A comparison study.

    Science.gov (United States)

    Hägg, Mary; Tibbling, Lita

    2015-09-01

    Training with either a palatal plate (PP) or an oral IQoro(R) screen (IQS) in patients with longstanding facial dysfunction and dysphagia after stroke can significantly improve facial activity (FA) in all four facial quadrants as well as swallowing capacity (SC). Improvements remained at late follow-up. The training modalities did not significantly differ in ameliorating facial dysfunction and dysphagia in these patients. However, IQS training has practical and economic advantages over PP training. This study compared PP and oral IQS training in terms of (i) effect on four-quadrant facial dysfunction and dysphagia after a first-ever stroke, and (ii) whether the training effect persisted at late follow-up. Patients were included during two periods; 13 patients in 2005-2008 trained with a PP, while 18 patients in 2009-2012 trained with an IQS. Four-quadrant facial dysfunction was assessed with an FA test and swallowing dysfunction with a SC test: before and after a 3-month training period and at late follow-up. FA and SC significantly improved (p stroke incidence and the start of training was long or short.

  10. A Case of Increased Density in Rabbit’s Jaw Bone, Evaluated by Cone-Beam Tomography

    Directory of Open Access Journals (Sweden)

    Srđan D. Poštić, PhD

    2013-06-01

    Full Text Available Reduced mineral content affects the trabecular microstructure in the jawbones and skeletons of animals. The aim of this study was to ascertain the benefits in terms of increased bone density in the region of the lateral teeth in the upper and the lower rabbit jaws after application of a therapeutic solution of calcitonin and calcium. The solution was injected to the right side of the maxilla and mandible on the lateral teeth, while the left side was the control. Statistically significant increases in density after application of the therapeutic solution were verified in the experimental regions, in front of the maxillary lateral teeth and around the first maxillary molar (Z=-3.824 and Z=-3.826; p=0.000. ANOVA testing has provided evidence on increasing bone density after the use of a therapeutic solution in the experimental regions of the bone (4.324; df1=7; df2=78.775; p=0.000. Cone beam computed technology (CBCT proved very reliable for assessing the jawbone density in animals, locally applying the additionally therapeutic solution for acceleration of the increment of bone density.

  11. Geographic modelling of jaw fracture rates in Australia: a methodological model for healthcare planning.

    Science.gov (United States)

    Kruger, Estie; Heitz-Mayfield, Lisa J A; Perera, Irosha; Tennant, Marc

    2010-06-01

    While Australians are one of the healthiest populations in the world, inequalities in access to health care and health outcomes exist for Indigenous Australians and Australians living in rural or urban areas of the country. Hence, the purpose of this study was to develop an innovative methodological approach for predicting the incidence rates of jaw fractures and estimating the demand for oral health services within Australia. Population data were obtained from the Australian Bureau of Statistics and was divided across Australia by statistical local area and related to a validated remoteness index. Every episode of discharge from all hospitals in Western Australia for the financial years 1999/2000 to 2004/2005 indicating a jaw fracture as the principle oral condition, as classified by the International Classification of Disease (ICD-10AM), was the inclusion criterion for the study. Hospitalization data were obtained from the Western Australian Hospital Morbidity Data System. The model estimated almost 10 times higher jaw fracture rates for Indigenous populations than their non-Indigenous counterparts. Moreover, incidence of jaw fractures was higher among Indigenous people living in rural and remote areas compared with their urban and semi-urban counterparts. In contrast, in the non-Indigenous population, higher rates of jaw fractures were estimated for urban and semi-urban inhabitants compared with their rural and remote counterparts. This geographic modelling technique could be improved by methodological refinements and further research. It will be useful in developing strategies for health management and reducing the burden of jaw fractures and the cost of treatment within Australia. This model will also have direct implications for strategic planning for prevention and management policies in Australia aimed at reducing the inequalities gap both in terms of geography as well as Aboriginality.

  12. SU-E-T-471: Small Field Jaw/MLC Reference Data

    International Nuclear Information System (INIS)

    Kerns, J; Alvarez, P; Followill, D; Lowenstein, J; Molineu, A; Summers, P; Kry, S

    2014-01-01

    Purpose: In recent years the need for small field data of MLCs has increased due to the use of intensity-modulated radiation (IMRT), but moreover the use of stereotactic body radiation (SBRT) has increased, which uses not simply small field sizes, but small jaw and field sizes together. Having reference data for these small fields that is reliable would be invaluable to the physics community. Our study has gathered these values and the data distributions from the Radiological Physics Center's (RPC) site visits between 1990 and the present. Methods: For all measurements, the RPC used a 25 × 25 × 25cm water phantom placed at 100cm SSD. All measurements were made with an Exradin A16 cylindrical ion chamber at an effective depth of 10 cm. A total of 42 Varian machine measurements were used to compose the data for a 6 MV beam and 5 TrueBeam 6 MV flattening filter free (FFF) beams were used for FFF data. Results: Jaw/MLC fields were measured for both 6 MV and 6 MF FFF beams with the jaws and MLCs both at the following field sizes: 6×6, 4×4, 3×3, and 2×2cm. Measurements were normalized to the 10×10 field readings (defined by the jaws and MLC). Spread in the data was minimal and demonstrates a high level of accuracy of acquired data. Conclusion: Small field Jaw/MLC reference data for Varian 6MV and 6 MV FFF beams has been analyzed and presented here, composed of the aggregation of numerous RPC site visits. Obtaining reliable small field data remains difficult, however the RPC has collected high fidelity small field Jaw/MLC data. The data are presented as a reference along with their distributions, in such a way that the physicist can act based upon their own desired agreement with the reference data

  13. Why Dora Left

    DEFF Research Database (Denmark)

    Gammelgård, Judy

    2017-01-01

    The question of why Dora left her treatment before it was brought to a satisfactory end and the equally important question of why Freud chose to publish this problematic and fragmentary story have both been dealt with at great length by Freud’s successors. Dora has been read by analysts, literary...... critics, and not least by feminists. The aim of this paper is to point out the position Freud took toward his patient. Dora stands out as the one case among Freud’s 5 great case stories that has a female protagonist, and reading the case it becomes clear that Freud stumbled because of an unresolved...... problem toward femininity, both Dora’s and his own. In Dora, it is argued, Freud took a new stance toward the object of his investigation, speaking from the position of the master. Freud presents himself as the one who knows, in great contrast to the position he takes when unraveling the dream. Here he...

  14. The Diagnosis and Management of Multiple Supernumerary Teeth Involving Both Jaws.

    Science.gov (United States)

    Öz, A Alper; Baş, Burcu; Öz, Aslihan Zeynep

    2015-01-01

    Supernumerary teeth are frequently seen anomalies however its occurrence in both jaws is rare without being associated with complex syndromes. This case report describes the orthodontic and surgical treatment of a 13-year-old boy with nonsyndromal multiple and abnormal supernumerary teeth. The patient had several erupted and unerupted supernumerary teeth involving both jaws. Two abnormal tuberculate type erupted supernumerary teeth were present at the site of upper central incisors which leads to the impaction of the permanent incisors. In this report, clinical and radiographic evaluation as well as the treatment alternatives of this rare case was presented.

  15. Polyostotic eosinophilic granuloma of the jaws treated by chemotherapy. A case report.

    Science.gov (United States)

    Abrahão, A C; Cabral, M G; Noce Dos Santos, C W; Janini, M E R; Pulcheri, W A

    2007-01-01

    Eosinophilic granuloma is classified as a Langerhans cell histiocytosis. Although considered a rare pathology, up to 20% of all cases occur in the jaw bones, and radiographically may mimic odontogenic cysts or benign and malignant tumours. Different protocols have been suggested in the literature for treating eosinophilic granuloma. We report a case of polyostotic eosinophilic granuloma in a 34-year-old man showing ill defined mandibular and palatal radiolucencies. Due to the presence of multiple jaw lesions the treatment choice was chemotherapy. The clinical and radiographic feature are described, as well as treatment, complications and patient's follow-up.

  16. Solitary Intra-Osseous Myofibroma of the Jaw: A Case Report and Review of Literature.

    Science.gov (United States)

    Dhupar, Anita; Carvalho, Karla; Sawant, Poonam; Spadigam, Anita; Syed, Shaheen

    2017-10-24

    Myofibroma is a rare benign spindle cell neoplasm in children that usually affects both soft tissue and bone in the head and neck region. Approximately one third of these cases are seen within jaw bones as solitary lesions. Solitary intra-osseous myofibroma of the jaw bone shares its clinical, radiographic and histological features with other spindle cell tumors. The rarity of this lesion can make diagnosis difficult for clinicians and pathologists. We report a case of a solitary intra-osseous myofibroma in the mandible of a nine-year-old child.

  17. [Osteomyelitis of the jaw in breast cancer patients receiving bisphosphonate therapy].

    Science.gov (United States)

    Tomihara, Kei; Nagai, Itaru; Yamaguchi, Akira; Miyazaki, Akihiro; Dehari, Hironari; Abe, Masato; Nakamori, Kenji; Komai, Kiyoto; Nakai, Mitsuyoshi; Hiratsuka, Hiroyoshi

    2008-01-01

    Osteonecrosis of the jaw is a severe new complication in cancer patients with bone metastases receiving bisphosphonate. Currently, there is no effective treatment for bisphosphonate-related osteonecrosis of the jaw, and the pathogenesis of this complication has not been completely elucidated. It has been shown that a potential risk factor for the complication is dentoalveolar trauma including extraction of teeth during bisphosphonate therapy. Attention should be paid to dental care in patients prior to the initiation of bisphosphonate therapy, and extraction of teeth during bisphosphonate therapy should be avoided to prevent this complication. Therefore, the communication between general physicians prescribing bisphosphonate and dentists is important.

  18. Correction to: Cone beam computed tomography and ultrasonography imaging of benign intraosseous jaw lesion: a prospective radiopathological study.

    Science.gov (United States)

    Bayrakdar, Ibrahim Sevki; Yilmaz, Ahmet Berhan; Caglayan, Fatma; Ertas, Umit; Gundogdu, Cemal; Gumussoy, Ismail

    2018-02-08

    In the original version of this article, '123 lytic intraosseous jaw lesions diagnosed in 112 patients' was incorrectly presented as '123 lytic intraosseous jaw lesions diagnosed in 121 patients' and 'an average age of 31.7 ± 15.4 (range, 6-72)' was incorrectly presented as 'average age of 15.4 ± 31.7 (range, 6-72)'.

  19. Diagnostic sensitivity and specificity in a retrospective clinical, radiographic and histopathological study of 166 cystic jaw lesions

    DEFF Research Database (Denmark)

    Therkildsen, N. M.; Andersen, Kristian; Blomlôf, J.

    2014-01-01

    analyses of clinical, radiographic and histopathological records of 166 patients diagnosed with, and treated for, cystic jaw lesions at the Department of Oral and Maxillofacial Surgery, Aarhus University Hospital from 2005 to 2010. Results Specificity was generally high for all cystic jaw lesions...

  20. Osteonecrosis of the jaw as a possible rare side effect of annual bisphosphonate administration for osteoporosis: A case report

    Directory of Open Access Journals (Sweden)

    Ehrenfeld Michael

    2011-09-01

    Full Text Available Abstract Introduction Osteonecrosis of the jaw is a serious side effect in patients receiving nitrogen-containing bisphosphonates intravenously due to malignant diseases. Albeit far less frequently, osteonecrosis of the jaw has also been reported to occur due to the oral administration of nitrogen-containing bisphosphonates due to osteoporosis. Annual infusions of zoledronic acid have been recommended in order to improve patient compliance, to optimize therapeutic effects and to minimize side effects. To date, osteonecrosis of the jaw has not been linked to the annual administration of bisphosphonates. Case presentation We report the case of a 65-year-old Caucasian woman suffering from osteoporosis who developed early stage osteonecrosis of the jaw in two locations, with chronic infections, after two months of oral bisphosphonate treatment and three annual administrations of zoledronic acid. Our patient was treated by fluorescence-guided resection of the necrotic jaw bone areas; local inflammation was treated by removal of a wisdom tooth and repeat root resections. Histopathology revealed typical hallmarks of osteonecrosis of the jaw. Conclusion Osteonecrosis of the jaw may occur as a consequence of annual administrations of zoledronic acid. It is conceivable that, due to the pharmacological properties of bisphosphonates, a jaw bone that encounters frequent local inflammations is more likely to develop osteonecrosis.

  1. Extraction socket healing in rats treated with bisphosphonate: animal model for bisphosphonate related osteonecrosis of jaws in multiple myeloma patients.

    Science.gov (United States)

    Ali-Erdem, Mehmet; Burak-Cankaya, Abdulkadir; Cemil-Isler, Sabri; Demircan, Sabit; Soluk, Merva; Kasapoglu, Cetin; Korhan-Oral, Cuneyt

    2011-11-01

    The aim of this study is to replicate both clinical and histological presentation of bisphosphonate induced osteonecrosis of the jaws (BONJ) in an animal model of the disease state. Successful recapitulation of a BONJ-like indication in an animal model will be useful for studying pathogenesis, as well as prevention and treatment strategies for BONJ. Eighty (80) rats were prospectively and randomly divided into two groups; control group(40) and study group(40). All animals in study group, injected with a dose of 1 mg/kg dexamethasone (DX) subcutaneously on day 7, 14, or 21; and 1, 2, or 3 doses of 7.5 µg/kg zoledronic acid (ZA) subcutaneously administered to coincide with the last day of DX. Half of the animals from each group underwent extraction of the left mandibular molars and the remaining animals underwent extraction of the left maxillary molars under pentobarbital-induced general anesthesia. All animals were euthanized twenty-eight (28) days following tooth extractions. The amount of new bone trabecules as significantly decreased in bisphosphonate-dexamethasone (BP-DX) treated sockets. Difference between both groups was found statistically significant (p=0,0001). There's no foreign body reaction in sockets of both groups and no significance difference observed for fibrosis (p=0,306). The necrosis scores were significantly higher in BP-DX treated sockets (p=0,015). The inflamation scores were significantly higher for study group (p=0,0001). This study provides preliminary observations for the development of an animal model of BONJ. But we think that there is need for other studies have only BP treated group and larger study population.

  2. Non-compact left ventricle/hypertrabeculated left ventricle

    International Nuclear Information System (INIS)

    Restrepo, Gustavo; Castano, Rafael; Marmol, Alejandro

    2005-01-01

    Non-compact left ventricle/hypertrabeculated left ventricle is a myocardiopatie produced by an arrest of the normal left ventricular compaction process during the early embryogenesis. It is associated to cardiac anomalies (congenital cardiopaties) as well as to extracardial conditions (neurological, facial, hematologic, cutaneous, skeletal and endocrinological anomalies). This entity is frequently unnoticed, being diagnosed only in centers with great experience in the diagnosis and treatment of myocardiopathies. Many cases of non-compact left ventricle have been initially misdiagnosed as hypertrophic myocardiopatie, endocardial fibroelastosis, dilated cardiomyopatie, restrictive cardiomyopathy and endocardial fibrosis. It is reported the case of a 74 years old man with a history of chronic arterial hypertension and diabetes mellitus, prechordial chest pain and mild dyspnoea. An echocardiogram showed signs of non-compact left ventricle with prominent trabeculations and deep inter-trabecular recesses involving left ventricular apical segment and extending to the lateral and inferior walls. Literature on this topic is reviewed

  3. Segmental omental infarction in childhood: an unusual case of left-sided location with extension into the pelvis

    International Nuclear Information System (INIS)

    Foscolo, Sylvain; Mandry, Damien; Galloy, Marie-Agnes; Claudon, Michel; Champigneulles, Jacqueline; Miscault, Godefroy de

    2007-01-01

    Segmental omental infarction (OI) is a rare cause of abdominal pain in children. It generally occurs in the right lower and upper quadrants of the abdomen and only a few cases of other locations have been described in adults. We report a unique paediatric case of OI with an unusual left-sided location extending into the pelvis in a 6-year-old non-obese girl. The diagnosis was suspected on US and CT based on imaging patterns previously described in adults and children. Laparoscopic resection should be balanced with nonsurgical management. (orig.)

  4. Investigation of Pitch and Jaw Width to Decrease Delivery Time of Helical Tomotherapy Treatments for Head and Neck Cancer

    International Nuclear Information System (INIS)

    Moldovan, Monica; Fontenot, Jonas D.; Gibbons, John P.; Lee, Tae Kyu; Rosen, Isaac I.; Fields, Robert S.; Hogstrom, Kenneth R.

    2011-01-01

    Helical tomotherapy plans using a combination of pitch and jaw width settings were developed for 3 patients previously treated for head and neck cancer. Three jaw widths (5, 2.5, and 1 cm) and 4 pitches (0.86, 0.43, 0.287, and 0.215) were used with a (maximum) modulation factor setting of 4. Twelve plans were generated for each patient using an identical optimization procedure (e.g., number of iterations, objective weights, and penalties, etc.), based on recommendations from TomoTherapy (Madison, WI). The plans were compared using isodose plots, dose volume histograms, dose homogeneity indexes, conformity indexes, radiobiological models, and treatment times. Smaller pitches and jaw widths showed better target dose homogeneity and sparing of normal tissue, as expected. However, the treatment time increased inversely proportional to the jaw width, resulting in delivery times of 24 ± 1.9 min for the 1-cm jaw width. Although treatment plans produced with the 2.5-cm jaw were dosimetrically superior to plans produced with the 5-cm jaw, subsequent calculations of tumor control probabilities and normal tissue complication probabilities suggest that these differences may not be radiobiologically meaningful. Because treatment plans produced with the 5-cm jaw can be delivered in approximately half the time of plans produced with the 2.5-cm jaw (5.1 ± 0.6 min vs. 9.5 ± 1.1 min), use of the 5-cm jaw in routine treatment planning may be a viable approach to decreasing treatment delivery times from helical tomotherapy units.

  5. Mechanical discordance between left atrium and left atrial appendage

    Directory of Open Access Journals (Sweden)

    Arash Khamooshian

    2018-01-01

    Full Text Available During standard transesophageal echocardiographic examinations in sinus rhythm (SR patients, the left atrial appendage (LAA is not routinely assessed with Doppler. Despite having a SR, it is still possible to have irregular activity in the LAA. This situation is even more important for SR patients where assessment of the left atrium is often foregone. We describe a case where we encountered this situation and briefly review how to assess the left atrium and its appendage in such a case scenario.

  6. [Left-handedness and health].

    Science.gov (United States)

    Milenković, Sanja; Belojević, Goran; Kocijancić, Radojka

    2010-01-01

    Hand dominance is defined as a proneness to use one hand rather than another in performing the majority of activities and this is the most obvious example of cerebral lateralization and an exclusive human characteristic. Left-handed people comprise 6-14% of the total population, while in Serbia, this percentage is 5-10%, moving from undeveloped to developed environments, where a socio-cultural pressure is less present. There is no agreement between investigators who in fact may be considered a left-handed person, about the percentage of left-handers in the population and about the etiology of left-handedness. In the scientific literature left-handedness has been related to health disorders (spine deformities, immunological disorders, migraine, neurosis, depressive psychosis, schizophrenia, insomnia, homosexuality, diabetes mellitus, arterial hypertension, sleep apnea, enuresis nocturna and Down Syndrome), developmental disorders (autism, dislexia and sttutering) and traumatism. The most reliable scientific evidences have been published about the relationship between left-handedness and spinal deformities in school children in puberty and with traumatism in general population. The controversy of other results in up-to-now investigations of health aspects of left-handedness may partly be explained by a scientific disagreement whether writing with the left hand is a sufficient criterium for left-handedness, or is it necessary to investigate other parameters for laterality assessment. Explanation of health aspects of left-handedness is dominantly based on Geschwind-Galaburda model about "anomalous" cerebral domination, as a consequence of hormonal disbalance.

  7. Normal serum bone markers in bisphosphonate-induced osteonecrosis of the jaws.

    Science.gov (United States)

    Lehrer, Steven; Montazem, André; Ramanathan, Lakshmi; Pessin-Minsley, Melissa; Pfail, John; Stock, Richard G; Kogan, Rita

    2008-09-01

    We obtained serum bone markers and other relevant endocrine assays on 5 patients with osteonecrosis of the jaw (ONJ). The assays were C-telopeptide, N-telopeptide, bone-specific alkaline phosphatase, osteocalcin, intact parathyroid hormone, T3, T4, TSH, and Vitamin D 25 hydroxy. Diagnostic criteria for ONJ were those formulated by the American Association of Oral and Maxillofacial Surgeons. Four of our patients were women. Two had metastatic breast cancer and had been treated with zoledronic acid; one had also received pamidronate. Two others had osteoporosis and had been treated with daily alendronate. One man had metastatic prostate cancer treated with zoledronic acid. All patients had been withdrawn from bisphosphonate for at least 6 months. None were taking or had taken corticosteroids. None of the lesions had shown any significant healing and all were still causing the patients considerable distress. Yet the bone markers were within the normal range as measured in our laboratory, except for intact parathyroid hormone, which was slightly elevated in one case of metastatic breast cancer (177 pg/mL). Because the jaws have a greater blood supply than other bones, and a high bone turnover rate, bisphosphonates are highly concentrated in the jaws. This anatomic concentration of bisphosphonates might cause bisphosphonate-osteonecrosis to be manifested exclusively in the jaws and is consistent with our finding of normal serum bone markers in ONJ patients.

  8. Ameloblastomatous change in radicular cyst of the jaw in a Nigerian ...

    African Journals Online (AJOL)

    Objective: To determine the incidence, age, gender, jaw-sites and subtypes of radicular cyst, and to determine the incidence of ameloblastomatous change in radicular cyst in a Nigerian population. Method: A 10-year retrospective analysis of all diagnosed orofacial lesions in the Department of Oral Pathology and Medicine, ...

  9. Postnatal development of fiber type composition in rabbit jaw and leg muscles

    NARCIS (Netherlands)

    Korfage, J. A. M.; Helmers, R.; Matignon, M. de Goüyon; van Wessel, T.; Langenbach, G. E. J.; van Eijden, T. M. G. J.

    2009-01-01

    We examined the difference in fiber type composition and cross-sectional areas during postnatal development in male rabbit jaw muscles and compared these with changes in leg muscles. The myosin heavy chain (MyHC) content of the fibers was determined by immunohistochemistry. No fiber type difference

  10. Osteosarcoma: A Comparison of Jaw versus Nonjaw Localizations and Review of the Literature

    Directory of Open Access Journals (Sweden)

    H. van den Berg

    2013-01-01

    Full Text Available Purpose. It is assumed that osteosarcomas of the jaws mainly occur at older ages, whereas the most prominent sites, that is, the long bones, are more affected at ages 60 years. Poorer outcome in older people is likely due to refraining from chemotherapy.

  11. Myxoma of the Jaw Bones: Analysis of 27 Cases | Ajike | Nigerian ...

    African Journals Online (AJOL)

    Twenty-seven patients with histologically confirmed cases of odontogenic myxoma of the jaws were managed in a 10-year period. They represent 8.5% of all odontogenic tumours seen during the period. There was a female preponderance with the female to male ratio of 2.4:1. The age range was 11-70 years with majority ...

  12. Clinicohistopathological analysis of 5 Nigerian cases of malignant fibrous histiocytoma of the jaws.

    Science.gov (United States)

    Effiom, O A; Ajayi, O F; Nwoga, M C; Ogundana, O M; Adeyemo, W L; Kolade, M T

    2012-01-01

    Malignant fibrous histiocytoma (MFH), is a soft tissue sarcoma that occurs predominantly in the soft tissue of the extremities. It rarely occurs in facial bones. Few cases in the jaws have been reported. To report and review the relevant clinicopathologic features of 5 cases of jaw MFHin Nigerians. All cases in the records of the Department of Oral Pathology of the Lagos University Teaching Hospital which were histologically diagnosed as MFH were retrieved. Hematoxylin and eosin slides of cases were re-examined to confirm diagnosis. Information retrieved included age, sex, location, x-ray, estimated duration, recurrence, and histological presentation. Data was analyzed using SPSS statistical package. Age ranged between 12-42 years with a male sex predilection (3 cases/60.0%) and sole maxillary site predilection (5 cases/100.0%). Estimated duration of lesion ranged from 2 -12 months. Two cases recurred post surgical treatment. All cases presented as the storiform-pleomorphic type with one case presenting with a delicate/scanty connective tissue stroma. Chronic inflammation was scanty in the two cases that recurred. MFH of the jaws is rare among Nigerians. Its clinico radiological presentation maymimick other more aggressive or less benign lesions of the jaws thereby resulting in misdiagnosis and in appropriate patient management.

  13. Time to onset of bisphosphonate-related osteonecrosis of the jaws

    DEFF Research Database (Denmark)

    Fung, Ppl; Bedogni, G; Bedogni, A

    2017-01-01

    OBJECTIVES: Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect of bisphosphonates (BP). Although the risk of ONJ increases with increasing duration of BP treatment, there are currently no reliable estimates of the ONJ time to onset (TTO). The objective of this study was to esti...

  14. Differential diagnosis of cysts and cyst-like lesions of the jaw

    Energy Technology Data Exchange (ETDEWEB)

    Herzog, M.; Beyer, D.; Zanella, F.

    1985-08-01

    The difficulties in the differential diagnosis of jaw cysts are demonstrated by 10 selected case studies. Panorama radiographies are basic for radiodiagnosis, including CT, are often necessary. In general, the final diagnosis can be given after synopsis of clinical, radiographic and patho-histological findings.

  15. Speech in ALS: Longitudinal Changes in Lips and Jaw Movements and Vowel Acoustics.

    Science.gov (United States)

    Yunusova, Yana; Green, Jordan R; Lindstrom, Mary J; Pattee, Gary L; Zinman, Lorne

    2013-03-01

    The goal of this exploratory study was to investigate longitudinally the changes in facial kinematics, vowel formant frequencies, and speech intelligibility in individuals diagnosed with bulbar amyotrophic lateral sclerosis (ALS). This study was motivated by the need to understand articulatory and acoustic changes with disease progression and their subsequent effect on deterioration of speech in ALS. Lip and jaw movements and vowel acoustics were obtained for four individuals with bulbar ALS during four consecutive recording sessions with an average interval of three months between recordings. Participants read target words embedded into sentences at a comfortable speaking rate. Maximum vertical and horizontal mouth opening and maximum jaw displacements were obtained during corner vowels. First and second formant frequencies were measured for each vowel. Speech intelligibility and speaking rate score were obtained for each session as well. Transient, non-vowel-specific changes in kinematics of the jaw and lips were observed. Kinematic changes often preceded changes in vowel acoustics and speech intelligibility. Nonlinear changes in speech kinematics should be considered in evaluation of the disease effects on jaw and lip musculature. Kinematic measures might be most suitable for early detection of changes associated with bulbar ALS.

  16. Oral Bisphosphonate Use Increases the Risk for Inflammatory Jaw Disease: A Cohort Study

    DEFF Research Database (Denmark)

    Vestergaard, Peter; Schwartz, Kristoffer; Rejnmark, Lars

    2011-01-01

    to compare the rate of inflammatory jaw-related events, ie, osteomyelitis, osteitis, periostitis, or sequestrum, between Danish patients who had been prescribed oral bisphosphonates (BP) and other drugs for the treatment of osteoporosis between 1996 and 2006 (the exposed group), and a random sample...

  17. Computer tomography valorization of the vascular lingual channels in the jaw

    International Nuclear Information System (INIS)

    Costantino, Sebastian; Capiel, Carlos h; Bouzas, Carlos; Vuotto, Miguel; Ferrari, Daniela; Bazzano, Sebastian

    2006-01-01

    Purpose: To determine the frequency, location and position of vascular lingual channels of jaw by dental CT and classifying them based on its location. Material and methods: Dental CT of 100 consecutive patients were reevaluated as previous evaluation to the positioning of dental implants. They are classified by linking their location on the jaw with the number of tooth present or absent in that area. Results: All patients had at least one lingual vascular channel in the jaw; 36 patients presented two channels, eight patients presented three and a patient presented four. The more frequent location was between the sectors of the pieces 31 and 41. Sixteen patients showed two channels (superior and inferior) in that location. The second location by frequency was between pieces 32 and 33 (nine patients). The average distance between the lingual surface of the alveolar rim and the vascular channels was of 16 mm. Conclusion: the dental CT is an excellent method for the identification of the vascular lingual channels by its multiplanar capacity and appropriate image resolution. The characterization and classification of these conduits by a method of easy reading for the radiologists and the dentists assure a correct pre surgical valuation avoiding hemorrhages during the jaw perforation in the positioning of dental implants. (author) [es

  18. The importance of dental CT for implantation in mouth, jaw, and face surgery

    International Nuclear Information System (INIS)

    Widlitzek, H.; Koenig, S.; Golin, U.

    1996-01-01

    The importance of dental CT in comparison to conventional OPT in implantation diagnostics is demonstrated in specific indication groups (atrophy of upper and lower jaw, patient after tumor and reconstructive surgery). The application of radiological techniques is illustrated in relation to diagnostic information quality, radiation exposure and cost effectiveness regarding clinical routine use. (orig.) [de

  19. New look at the anatomy of the jaws by dental CT imaging

    International Nuclear Information System (INIS)

    Nikolov, V.

    2006-01-01

    Full text: We represent a part of a retrospective study of CT findings of the jaws and teeth's by Dental CT. For preoperative planning in dental implantology, 215 jaws of 169 patients was investigated. There have been established the reasons for the lost of teeth's, the exact anatomical situation, the height and the vestibular-lingual thickness of the alveolar crest, the thickness of the cortical bone, the presence and volume of the bone defects, the bone mineral density in the implantation zone. A try has been made to create a mathematic model for calculating the risk of failed osseointegration. The investigating of jaws and teeth by Dental CT made it possible to find and localize excessive vascular canals in the frontal parts of the mandible, which is important to prevent complications in operative insertion of implants. There is a high percentage of patients with a great vestibular cortical resorption in the incisive and premolar region of both jaws. The existence of such similar situation in younger patients without periodontal disease

  20. [Numb chin syndrome caused by biphosphonates-induced osteonecrosis of the jaw].

    Science.gov (United States)

    Sierra-Hidalgo, F; de Pablo-Fernández, E; Correas-Callero, E; Villarejo-Galende, A

    Numb chin syndrome is caused by a mental or inferior alveolar nerve neuropathy. Traumatic and infectious injuries are the most frequent causes of the syndrome but, if an evident cause does not exist, a neoplastic etiology must be investigated. Other causes of the numb chin syndrome are rare. A 73-year-old woman had had a diagnosis of metastatic breast cancer and was been treated with zoledronic acid. She attended because of hypoesthesia and dysesthesia of the chin congruent with mental nerve distribution. A computed tomography of the jaw showed an osteolytic lesion with central bone sequestration, so biphosphonate-induced osteonecrosis of the jaw was diagnosed. After zoledronic acid was withdrawn, clinical neuropathy and imaging findings remained stable. Biphosphonates-induced osteonecrosis of the jaw is a recently described condition. It has been rarely reported as a cause for numb chin syndrome. In the future, osteonecrosis of the jaw must be considered in the differential diagnosis of this syndrome in cancer patients treated with biphosphonates.

  1. Bisphosphonates are associated with increased risk for jaw surgery in medical claims data: is it osteonecrosis?

    Science.gov (United States)

    Zavras, Athanasios I; Zhu, Shao

    2006-06-01

    Bisphosphonates (BPs) have recently been associated with increased risk of osteonecrosis of the jaw. Using a large automated insurance database, we searched the medical claims for common procedure codes (CPT codes) denoting major surgery to the mandible or the maxilla. The primary aim of this pilot study was to alert readers to clinically relevant but preliminary information regarding the risk of jaw surgery among patients who received BPs, as compared with patients who did not. The study utilized 2001-2004 claims data from a large nationwide medical insurer. Medical claims from 255,757 cancer patients with breast, lung, or prostate malignancies, or multiple myeloma were analyzed for CPT codes 21015, 21025, 21026, 21034, 21040, 21045, 21046, and 21047. We identified 224 cases of jaw surgery; of those, 39 cases were found among 26,288 BP users and 185 cases were found among 229,469 never-users. The odds ratio of jaw surgery for intravenous BP users was 4.24 (PBreast cancer patients experienced a 6-fold increase in risk as compared with nonusers. A trend of increased risk was noted for those on orally administered BPs, but the association was not significant. A significant association was noted between the administration of IV BPs and oral surgery in cancer patients. More studies are needed to understand the role of BPs in bone biology and necrosis along with the associated biologic pathways.

  2. Dosimetric effect on pediatric conformal treatment plans using dynamic jaw with Tomotherapy HDA

    Energy Technology Data Exchange (ETDEWEB)

    Han, Eun Young, E-mail: eyhan@uams.edu [Department of Radiation Oncology, University of Arkansas Medical Sciences, Little Rock, AR (United States); Kim, Dong-Wook [Department of Radiation Oncology, Kyung Hee University Hospital, Seoul (Korea, Republic of); Zhang, Xin; Penagaricano, Jose; Liang, Xiaoying; Hardee, Matthew; Morrill, Steve; Ratanatharathorn, Vaneerat [Department of Radiation Oncology, University of Arkansas Medical Sciences, Little Rock, AR (United States)

    2015-10-01

    It is important to minimize the radiation dose delivered to healthy tissues in pediatric cancer treatment because of the risk of secondary malignancies. Tomotherapy HDA provides a dynamic jaw (DJ) delivery mode that creates a sharper penumbra at the craniocaudal ends of a target in addition to a fixed jaw (FJ) delivery mode. The purpose of this study was to evaluate its dosimetric effect on the pediatric cancer cases. We included 6 pediatric cases in this study. The dose profiles and plan statistics—target dose conformity, uniformity, organ-at-risk (OAR) mean dose, beam-on time, and integral dose—were compared for each case. Consequently, the target dose coverage and uniformity were similar for different jaw settings. The OAR dose sparing depended on its relative location to the target and disease sites. For example, in the head and neck cancer cases, the brain stem dose using DJ 2.5 was reduced by more than two-fold (2.4 Gy vs. 6.3 Gy) than that obtained with FJ 2.5. The integral dose with DJ 2.5 decreased by more than 9% compared with that with FJ 2.5. Thus, using dynamic jaw in pediatric cases could be critical to reduce a probability of a secondary malignancy.

  3. Periapical lesions of the jaws: A review of 104 cases in Ibadan ...

    African Journals Online (AJOL)

    Background: Periapical lesions (PLs) occur as a result of pulpal inflammation and may rarely be seen in the absence of pulpal diseases. They are the most common pathological lesions affecting the alveolar bone. Objective: This study aims to describe the clinicopathological features of PLs of the jaws with emphasis on the ...

  4. Teriparatide and the treatment of bisphosphonate-related osteonecrosis of the jaw: a rat model

    NARCIS (Netherlands)

    Ersan, N.; van Ruijven, L.J.; Bronckers, A.L.J.J.; Olgaç, V.; Ìlgüy, D.; Everts, V.

    2014-01-01

    Objectives: The objectives of this study were to establish a bisphosphonate-related osteonecrosis of the jaw (BRONJ) rat model and to analyse the effects of teriparatide (TP) on this model. Methods: Sprague-Dawley rats were divided into three groups: I—zoledronic acid (ZA, n = 10); II—ZA and

  5. The effect of food bolus location on jaw movement smoothness and masticatory efficiency

    NARCIS (Netherlands)

    Molenaar, W.N.B.; Gezelle Meerburg, P.J.; Luraschi, J.; Whittle, T.; Schimmel, M.; Lobbezoo, F.; Peck, C.C.; Murray, G.M.; Minami, I.

    2012-01-01

    Masticatory efficiency in individuals with extensive tooth loss has been widely discussed. However, little is known about jaw movement smoothness during chewing and the effect of differences in food bolus location on movement smoothness and masticatory efficiency. The aim of this study was to

  6. Beam feasibility study of a collimator with in-jaw beam position monitors

    Energy Technology Data Exchange (ETDEWEB)

    Wollmann, Daniel, E-mail: daniel.wollmann@cern.ch [CERN, Geneva (Switzerland); Nosych, Andriy A. [CERN, Geneva (Switzerland); Cockcroft Institute, Daresbury (United Kingdom); The University of Liverpool, Liverpool (United Kingdom); Valentino, Gianluca; Aberle, Oliver; Aßmann, Ralph W.; Bertarelli, Alessandro; Boccard, Christian; Bruce, Roderik; Burkart, Florian; Calvo, Eva; Cauchi, Marija; Dallocchio, Alessandro; Deboy, Daniel; Gasior, Marek; Jones, Rhodri; Kain, Verena; Lari, Luisella; Redaelli, Stefano; Rossi, Adriana [CERN, Geneva (Switzerland)

    2014-12-21

    At present, the beam-based alignment of the LHC collimators is performed by touching the beam halo with both jaws of each collimator. This method requires dedicated fills at low intensities that are done infrequently and makes this procedure time consuming. This limits the operational flexibility, in particular in the case of changes of optics and orbit configuration in the experimental regions. The performance of the LHC collimation system relies on the machine reproducibility and regular loss maps to validate the settings of the collimator jaws. To overcome these limitations and to allow a continuous monitoring of the beam position at the collimators, a design with jaw-integrated Beam Position Monitors (BPMs) was proposed and successfully tested with a prototype (mock-up) collimator in the CERN SPS. Extensive beam experiments allowed to determine the achievable accuracy of the jaw alignment for single and multi-turn operation. In this paper, the results of these experiments are discussed. The non-linear response of the BPMs is compared to the predictions from electromagnetic simulations. Finally, the measured alignment accuracy is compared to the one achieved with the present collimators in the LHC.

  7. Beam feasibility study of a collimator with in-jaw beam position monitors

    Science.gov (United States)

    Wollmann, Daniel; Nosych, Andriy A.; Valentino, Gianluca; Aberle, Oliver; Aßmann, Ralph W.; Bertarelli, Alessandro; Boccard, Christian; Bruce, Roderik; Burkart, Florian; Calvo, Eva; Cauchi, Marija; Dallocchio, Alessandro; Deboy, Daniel; Gasior, Marek; Jones, Rhodri; Kain, Verena; Lari, Luisella; Redaelli, Stefano; Rossi, Adriana

    2014-12-01

    At present, the beam-based alignment of the LHC collimators is performed by touching the beam halo with both jaws of each collimator. This method requires dedicated fills at low intensities that are done infrequently and makes this procedure time consuming. This limits the operational flexibility, in particular in the case of changes of optics and orbit configuration in the experimental regions. The performance of the LHC collimation system relies on the machine reproducibility and regular loss maps to validate the settings of the collimator jaws. To overcome these limitations and to allow a continuous monitoring of the beam position at the collimators, a design with jaw-integrated Beam Position Monitors (BPMs) was proposed and successfully tested with a prototype (mock-up) collimator in the CERN SPS. Extensive beam experiments allowed to determine the achievable accuracy of the jaw alignment for single and multi-turn operation. In this paper, the results of these experiments are discussed. The non-linear response of the BPMs is compared to the predictions from electromagnetic simulations. Finally, the measured alignment accuracy is compared to the one achieved with the present collimators in the LHC.

  8. Benign tumors and tumor-like lesions of the oral cavity and jaws: An ...

    African Journals Online (AJOL)

    Purpose: The purpose was to examine the prevalence, gender, age and site(s) of odontogenic and nonodontogenic benign tumors, and tumor‑like lesions occurring in the oral cavity and jaws in a Turkish population, particularly, in the Eastern Turkey, and to compare findings of this study with other reports. Materials and ...

  9. Renal osteodystrophy with facial hyperostosis and 'rubber jaw' in an adult dog.

    Science.gov (United States)

    Kyle, M G; Davis, G B; Thompson, K G

    1985-07-01

    A nine-year-old male Sheltie dog was presented with bilaterally symmetrical maxilliary swelling, loose teeth and flexible mandibles. The condition was progressive over a period of two months. Biochemical and histopathological examinations supported a diagnosis of renal osteodystrophy with facial hyperostosis and 'rubber jaw'.

  10. Annual reversible plasticity of feeding structures: cyclical changes of jaw allometry in a sea urchin.

    Science.gov (United States)

    Ebert, Thomas A; Hernández, José Carlos; Clemente, Sabrina

    2014-03-22

    A wide variety of organisms show morphologically plastic responses to environmental stressors but in general these changes are not reversible. Though less common, reversible morphological structures are shown by a range of species in response to changes in predators, competitors or food. Theoretical analysis indicates that reversible plasticity increases fitness if organisms are long-lived relative to the frequency of changes in the stressor and morphological changes are rapid. Many sea urchin species show differences in the sizes of jaws (demi-pyramids) of the feeding apparatus, Aristotle's lantern, relative to overall body size, and these differences have been correlated with available food. The question addressed here is whether reversible changes of relative jaw size occur in the field as available food changes with season. Monthly samples of the North American Pacific coast sea urchin Strongylocentrotus purpuratus were collected from Gregory Point on the Oregon (USA) coast and showed an annual cycle of relative jaw size together with a linear trend from 2007 to 2009. Strongylocentrotus purpuratus is a long-lived species and under field conditions individuals experience multiple episodes of changes in food resources both seasonally and from year to year. Their rapid and reversible jaw plasticity fits well with theoretical expectations.

  11. Report of six cases of metastatic jaw tumours in Nigerians | Adebayo ...

    African Journals Online (AJOL)

    These complaints resemble those from odontogenic infections and benign neoplasms. The most common histological type of metastatic tumours in this study was the adenocarcinoma (50%). Conclusion: In view of the similarity in presentation of metastatic lesions to the jaws and other odontogenic tumours and even ...

  12. A distribution of antero-posterior skeletal jaw relationship in 12-15 ...

    African Journals Online (AJOL)

    Objective: To determine the antero-posterior skeletal jaw relationship, in 12 -15 year old Nigerian school children in Benin city. Materials and Methods: Lateral cephalometric radiographs of 100 subjects aged 12-15 years with no history of orthodontic treatment were taken for this study. The radiographs were manually traced ...

  13. Adaptive phenotypic plasticity in the Midas cichlid fish pharyngeal jaw and its relevance in adaptive radiation

    Directory of Open Access Journals (Sweden)

    Salzburger Walter

    2011-04-01

    Full Text Available Abstract Background Phenotypic evolution and its role in the diversification of organisms is a central topic in evolutionary biology. A neglected factor during the modern evolutionary synthesis, adaptive phenotypic plasticity, more recently attracted the attention of many evolutionary biologists and is now recognized as an important ingredient in both population persistence and diversification. The traits and directions in which an ancestral source population displays phenotypic plasticity might partly determine the trajectories in morphospace, which are accessible for an adaptive radiation, starting from the colonization of a novel environment. In the case of repeated colonizations of similar environments from the same source population this "flexible stem" hypothesis predicts similar phenotypes to arise in repeated subsequent radiations. The Midas Cichlid (Amphilophus spp. in Nicaragua has radiated in parallel in several crater-lakes seeded by populations originating from the Nicaraguan Great Lakes. Here, we tested phenotypic plasticity in the pharyngeal jaw of Midas Cichlids. The pharyngeal jaw apparatus of cichlids, a second set of jaws functionally decoupled from the oral ones, is known to mediate ecological specialization and often differs strongly between sister-species. Results We performed a common garden experiment raising three groups of Midas cichlids on food differing in hardness and calcium content. Analyzing the lower pharyngeal jaw-bones we find significant differences between diet groups qualitatively resembling the differences found between specialized species. Observed differences in pharyngeal jaw expression between groups were attributable to the diet's mechanical resistance, whereas surplus calcium in the diet was not found to be of importance. Conclusions The pharyngeal jaw apparatus of Midas Cichlids can be expressed plastically if stimulated mechanically during feeding. Since this trait is commonly differentiated - among

  14. [Primary intraosseous carcinoma of the jaws: results of treatment of 9 cases and proposed classification].

    Science.gov (United States)

    Zwetyenga, N; Majoufre-Lefebvre, C; Pinsolle, V; Rivel, J; Faucher, A; Siberchicot, F

    2003-10-01

    Primary intraosseous carcinoma of the jaws is a rare squamous cell carcinoma arising in the jaw, having no initial connection with the oral mucosa and presumably developing from residues of the odontogenic epithelium. To present 9 cases and to propose a staging system of primary intraosseous carcinoma of the jaws. Careful assessment of the clinical, radiological and histological examination of the specimens identified 9 patients with primary intraosseous carcinoma of the jaws. The male/female ratio was 8/1 and the mean age of patients at the time of diagnosis was 61.7 years. All lesions were located in the mandible. Usually, clinical symptoms had benign aspect and delay the diagnosis. Radiographic features were unilocular osteolytic lesion and ill-defined margins were usually noted with a mean tumor size of 3.4 centimeters. The mean delay of the diagnosis was 4.9 months. Surgery at the tumor site consisted of hemi-mandibulectomy in all cases. All patients but one had neck dissection. The postoperative radiotherapy mean dose was 62.6 Gy. Histologically, most squamous cell carcinomas were well differentiated with keratinization. All lymph nodes metastasis had capsular involved. Complications occurred in 2 cases. Four patients had recurrences in the mean delay of 13.8 months. The estimated overall 2-and 5-years survival was 65% and 46.5% respectively. Primary intra-osseous carcinoma of the jaws is a rare tumor none classified by UICC with poor prognosis. We recommend an aggressive treatment with postoperative radiotherapy. We propose a computer tomographic classification: T1 (tumor strictly intra-osseous), T2 (tumor with cortical destruction without involvement of adjacent soft-tissues) and T3 (tumor involvement of adjacent soft-tissues).

  15. Paraneoplastic jaw dystonia and laryngospasm with antineuronal nuclear autoantibody type 2 (anti-Ri).

    Science.gov (United States)

    Pittock, Sean J; Parisi, Joseph E; McKeon, Andrew; Roemer, Shanu F; Lucchinetti, Claudia F; Tan, K Meng; Keegan, B Mark; Hunter, Samuel F; Duncan, Paul R; Baehring, Joachim M; Matsumoto, Joseph Y; Lennon, Vanda A

    2010-09-01

    Opsoclonus-myoclonus syndrome and breast carcinoma were initially described as neurologic and oncologic accompaniments of antineuronal nuclear autoantibody type 2 (ANNA-2, also known as anti-Ri). However, the neurologic spectrum of ANNA-2 autoimmunity is broader, includes a syndrome of jaw dystonia and laryngospasm, and can be accompanied by lung carcinoma. To describe clinically (with a video) ANNA-2-associated jaw dystonia and laryngospasm, its pathologic correlates, and therapeutic outcomes. Retrospective case series with prospective clinical follow-up. Mayo Clinic's Neuroimmunology Laboratory, Rochester, Minnesota. Consecutive patients with ANNA-2 seropositivity identified since January 1, 1990. Clinical (in 9 patients) and neuropathologic (in 2 patients) findings were reviewed. Of 48 patients with ANNA-2 seropositivity, 9 (19%) had multifocal neurologic manifestations that included jaw dystonia and laryngospasm. Among 6 patients with jaw dystonia, 5 had severely impaired nutrition, causing profound weight loss. Five patients had documented laryngospasm, which contributed to 1 patient's death. Neuropathologic examination revealed diffuse infiltration by CD8(+) T lymphocytes, with axonal loss and gliosis in brainstem and descending spinal cord tracts. Some patients improved symptomatically after immunosuppressant or cytotoxic therapies; 1 patient improved after treatment with botulinum toxin. One patient who underwent tracheostomy because of recurrent laryngospasm was alive and well longer than 3 years after symptom onset. Jaw dystonia and laryngospasm are common accompaniments of ANNA-2 autoimmunity and are associated with significant morbidity. We propose that selective damage to antigen-containing inhibitory fibers innervating bulbar motor nuclei by CD8(+) T lymphocytes (histopathologically observed infiltrating brainstem reticular formation) is the proximal cause of this syndrome. Early and aggressive therapy offers the prospect of neurologic improvement or

  16. Comparison of skin-sparing mastectomy using LigaSure™ Small Jaw and electrocautery.

    Science.gov (United States)

    Chang, Young Woo; Kim, Hwan Soo; Jung, Seung Pil; Woo, Sang Uk; Lee, Jae Bok; Bae, Jeoung Won; Son, Gil Soo

    2017-07-14

    Skin-sparing mastectomy (SSM) is increasingly used in patients with breast cancer. We compared the differences between use of electrocautery and LigaSure™ Small Jaw in patients with breast cancer who underwent SSM. Between January 2012 and December 2015, 81 patients with breast cancer who underwent SSM were selected and were divided into the electrocautery group and the LigaSure™ Small Jaw group based on the devices that were used. Clinicopathological characteristics, body mass index, operative time, and weight of removed breast were obtained from medical records. Total amount and days of drain use, until removal, and postoperative skin necrosis, requiring debridement, were also analyzed. The study population consisted of 50 patients in the electrocautery group and 31 in the LigaSure™ Small Jaw group. The latter group has significantly shorter operative time (117.5 ± 16.9 vs. 104.0 ± 23.6 min, P = 0.004). The mean total volume of drainage was less (805 ± 278 vs. 694 ± 131 mL, P = 0.017) and mean duration of drainage was also significantly shorter in the LigaSure™ Small Jaw group (11.3 ± 2.5 vs. 10.1 ± 2.0 days, P = 0.029). The use of LigaSure™ Small Jaw during skin-sparing mastectomy shortened the operative time and duration of drainage and reduced the total volume of drainage.

  17. A review on the use of sensors to monitor cattle jaw movements and behavior when grazing

    Directory of Open Access Journals (Sweden)

    Andriamandroso, ALH.

    2016-01-01

    Full Text Available Introduction. Precision Livestock Farming (PLF is spreading rapidly in intensive cattle farms. It is based on the monitoring of individuals using different kinds of sensors. Applied to grazing animals, PLF is mainly based on the recording of three parameters: the location, the posture and the movements of the animal. Until now, several techniques have been used to discriminate grazing and ruminating behaviors with accuracies over 90% on average, when compared to observations, providing valuable tools to improve the management of pasture and grazing animals. However, bites and jaw movements are still overlooked, even though they are of utmost importance to assess the animal grazing strategies for various pasture types and develop future techniques allowing better estimation of their intake. Literature. The goal of this review is to explore the possibility of monitoring the individual jaw movements and the differentiation of bites in grazing animals. For this purpose, (1 the mechanisms of forage intake in cattle are explained briefly in order to understand the movements performed by the cow, especially during grazing, (2 the various sensors that have been proposed to monitor jaw movements of ruminants such as mechanical sensors (pressure sensors, acoustic sensors (microphone and electromyography sensors are compared and (3 finally the relationship between jaw movements, biting behavior and forage intake is discussed. Conclusions. The review clearly demonstrated the abilities of mechanical, acoustic and electromyography sensors to classify the difference types of jaw movements. However, it also indicated a wide range of accuracies and different observation windows required to reach these accuracies when compared to the observed movement. This classification purpose could lead to a better detection of more specific behavior, e.g. bite detection, and their exact location on pasture.

  18. Experimental muscle pain produces central modulation of proprioceptive signals arising from jaw muscle spindles.

    Science.gov (United States)

    Capra, N F; Ro, J Y

    2000-05-01

    The aim of the present study was to investigate the effects of intramuscular injection with hypertonic saline, a well-established experimental model for muscle pain, on central processing of proprioceptive input from jaw muscle spindle afferents. Fifty-seven cells were recorded from the medial edge of the subnucleus interpolaris (Vi) and the adjacent parvicellular reticular formation from 11 adult cats. These cells were characterized as central units receiving jaw muscle spindle input based on their responses to electrical stimulation of the masseter nerve, muscle palpation and jaw stretch. Forty-five cells, which were successfully tested with 5% hypertonic saline, were categorized as either dynamic-static (DS) (n=25) or static (S) (n=20) neurons based on their responses to different speeds and amplitudes of jaw movement. Seventy-six percent of the cells tested with an ipsilateral injection of hypertonic saline showed a significant modulation of mean firing rates (MFRs) during opening and/or holding phases. The most remarkable saline-induced change was a significant reduction of MFR during the hold phase in S units (100%, 18/18 modulated). Sixty-nine percent of the DS units (11/16 modulated) also showed significant changes in MFRs limited to the hold phase. However, in the DS neurons, the MFRs increased in seven units and decreased in four units. Finally, five DS neurons showed significant changes of MFRs during both opening and holding phases. Injections of isotonic saline into the ipsilateral masseter muscle had little effect, but hypertonic saline injections made into the contralateral masseter muscle produced similar results to ipsilateral injections with hypertonic saline. These results unequivocally demonstrate that intramuscular injection with an algesic substance, sufficient to produce muscle pain, produces significant changes in the proprioceptive properties of the jaw movement-related neurons. Potential mechanisms involved in saline-induced changes in the

  19. Modulation of jaw muscle spindle afferent activity following intramuscular injections with hypertonic saline.

    Science.gov (United States)

    Ro, J Y; Capra, N F

    2001-05-01

    Transient noxious chemical stimulation of small diameter muscle afferents modulates jaw movement-related responses of caudal brainstem neurons. While it is likely that the effect is mediated from the spindle afferents in the mesencephalic nucleus (Vmes) via the caudally projecting Probst's tract, the mechanisms of pain induced modulations of jaw muscle spindle afferents is not known. In the present study, we tested the hypothesis that jaw muscle nociceptors gain access to muscle spindle afferents in the same muscle via central mechanisms and alter their sensitivity. Thirty-five neurons recorded from the Vmes were characterized as muscle spindle afferents based on their responses to passive jaw movements, muscle palpation, and electrical stimulation of the masseter nerve. Each cell was tested by injecting a small volume (250 microl) of either 5% hypertonic and/or isotonic saline into the receptor-bearing muscle. Twenty-nine units were tested with 5% hypertonic saline, of which 79% (23/29) showed significant modulation of mean firing rates (MFRs) during one or more phases of ramp-and-hold movements. Among the muscle spindle primary-like units (n = 12), MFRs of 4 units were facilitated, five reduced, two showed mixed responses and one unchanged. In secondary-like units (n = 17), MFRs of 9 were facilitated, three reduced and five unchanged. Thirteen units were tested with isotonic saline, of which 77% showed no significant changes of MFRs. Further analysis revealed that the hypertonic saline not only affected the overall output of muscle spindle afferents, but also increased the variability of firing and altered the relationship between afferent signal and muscle length. These results demonstrated that activation of muscle nociceptors significantly affects proprioceptive properties of jaw muscle spindles via central neural mechanisms. The changes can have deleterious effects on oral motor function as well as kinesthetic sensibility.

  20. REHABILITATION OF SEVERELY ATROPHIED UPPER JAW WITH INTRAOSSAL DENTAL IMPLANTS - clinical case

    Directory of Open Access Journals (Sweden)

    Ivan Chenchev

    2010-07-01

    Full Text Available Objective: The purpose of this presentation is to show the difficulty in prosthetization of a clinical case with a pronounced atrophy of the upper jaw and the various types and nature of restrictions imposed by the requirements of the patient. Methods: The clinical analysis, surgical protocol and prosthetic solution are presented in the treatment of 72 year-old woman with a pronounced atrophy of the upper jaw. OPG, standard CT of the upper jaw was used in the planning and a special surgical template was fabricated, helping us to find intraoperatively the exact locations of implants. The preliminary analysis of the number, height and diameter of intraossal implants helped us to find the exact prosthetic solution in this clinical case. The preparation of the implant bed was done by conical osteotomy in order to expand and condense the existing bone, which allowed us to use endoossal implants with a possible maximum size in a very limited maxillary volume and the reluctance of the patient to use other methods and surgical techniques. Conical threaded and self-tapping intraossal implants were used, placed according to a classic two-stage methodology with a flap and a long-term functional loading after a period of four months.Results and Conclusion: The applied surgical and prosthetic solution allowed us to achieve a good functional and aesthetic rehabilitation in this case of severe atrophy of the upper jaw, following a number of restrictions imposed on us by the reluctance of the patient to use other surgical solutions. This shows that in the case of severe atrophy of the upper jaw, a good clinical result can be achieved. For this reason, the use of CT,a well-planned surgical template, sufficient preparation ,the maximum use of available bone volume and the choice of a good prosthetic solution is very important.

  1. A case report of multiple cysts in the jaws

    International Nuclear Information System (INIS)

    Park, Tae Won; Lee, Sang Rae

    1973-01-01

    The authors have interpreted one patient's full mouth intra-oral films, oblique-lateral film of the left mandible and orthopantomograph which revealed 6 radicular and 1 residual cysts. As results of interpretation of these serial films, we have drawn following conclusions: 1. Radicular cyst arose from the cell rests contained in an apical granuloma which was sequel to advanced pulpitis due to dental caries. 2. Radicular cyst was developed from remaining cell rests after the extraction of a tooth with such a radicular cyst of apical dental granuloma. 3. Cyst grew in size by absorption of fluid into cystic cavity due to difference in osmotic pressure between the cystic fluid and adjacent tissue fluid.

  2. A case report of multiple cysts in the jaws

    Energy Technology Data Exchange (ETDEWEB)

    Park, Tae Won; Lee, Sang Rae [School of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    1973-11-15

    The authors have interpreted one patient's full mouth intra-oral films, oblique-lateral film of the left mandible and orthopantomograph which revealed 6 radicular and 1 residual cysts. As results of interpretation of these serial films, we have drawn following conclusions: 1. Radicular cyst arose from the cell rests contained in an apical granuloma which was sequel to advanced pulpitis due to dental caries. 2. Radicular cyst was developed from remaining cell rests after the extraction of a tooth with such a radicular cyst of apical dental granuloma. 3. Cyst grew in size by absorption of fluid into cystic cavity due to difference in osmotic pressure between the cystic fluid and adjacent tissue fluid.

  3. An interactive three dimensional approach to anatomical description—the jaw musculature of the Australian laughing kookaburra (Dacelo novaeguineae

    Directory of Open Access Journals (Sweden)

    Michelle R. Quayle

    2014-05-01

    Full Text Available The investigation of form-function relationships requires a detailed understanding of anatomical systems. Here we document the 3-dimensional morphology of the cranial musculoskeletal anatomy in the Australian Laughing Kookaburra Dacelo novaeguineae, with a focus upon the geometry and attachments of the jaw muscles in this species. The head of a deceased specimen was CT scanned, and an accurate 3D representation of the skull and jaw muscles was generated through manual segmentation of the CT scan images, and augmented by dissection of the specimen. We identified 14 major jaw muscles: 6 in the temporal group (M. adductor mandibulae and M. pseudotemporalis, 7 in the pterygoid group (M. pterygoideus dorsalis and M. pterygoideus ventralis, and the single jaw abductor M. depressor mandibulae. Previous descriptions of avian jaw musculature are hindered by limited visual representation and inconsistency in the nomenclature. To address these issues, we: (1 present the 3D model produced from the segmentation process as a digital, fully interactive model in the form of an embedded 3D image, which can be viewed from any angle, and within which major components can be set as opaque, transparent, or hidden, allowing the anatomy to be visualised as required to provide a detailed understanding of the jaw anatomy; (2 provide a summary of the nomenclature used throughout the avian jaw muscle literature. The approach presented here provides considerable advantages for the documentation and communication of detailed anatomical structures in a wide range of taxa.

  4. Modular AC Nano-Grid with Four-Quadrant Micro-Inverters and High-Efficiency DC-DC Conversion

    Science.gov (United States)

    Poshtkouhi, Shahab

    A significant portion of the population in developing countries live in remote communities, where the power infrastructure and the required capital investment to set up local grids do not exist. This is due to the fuel shipment and utilization costs required for fossil fuel based generators, which are traditionally used in these local grids, as well as high upfront costs associated with the centralized Energy Storage Systems (ESS). This dissertation targets modular AC nano-grids for these remote communities developed at minimal capital cost, where the generators are replaced with multiple inverters, connected to either Photovoltaic (PV) or battery modules, which can be gradually added to the nano-grid. A distributed droop-based control architecture is presented for the PV and battery Micro-Inverters (MIV) in order to achieve frequency and voltage stability, as well as active and reactive power sharing. The nano-grid voltage is regulated collectively in either one of four operational regions. Effective load sharing and transient handling are demonstrated experimentally by forming a nano-grid which consists of two custom 500 W MIVs. The MIVs forming the nano-grid have to meet certain requirements. A two-stage MIV architecture and control scheme with four-quadrant power-flow between the nano-grid, the PV/battery and optional short-term storage is presented. The short-term storage is realized using high energy-density Lithium-Ion Capacitor (LIC) technology. A real-time power smoothing algorithm utilizing LIC modules is developed and tested, while the performance of the 100 W MIV is experimentally verified under closed-loop dynamic conditions. Two main limitations of the DAB topology, as the core of the MIV architecture's dc-dc stage, are addressed: 1) This topology demonstrates poor efficiency and limited regulation accuracy at low power. These are improved by introducing a modified topology to operate the DAB in Flyback mode, achieving up to an 8% increase in

  5. Interventions for managing medication-related osteonecrosis of the jaw.

    Science.gov (United States)

    Beth-Tasdogan, Natalie H; Mayer, Benjamin; Hussein, Heba; Zolk, Oliver

    2017-10-06

    Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab and antiangiogenic agents) and involves the progressive destruction of bone in the mandible or maxilla. Depending on the drug, its dosage, and the duration of exposure, the occurrence of this adverse drug reaction may be rare (e.g. following the oral administration of bisphosphonate or denosumab treatments for osteoporosis, or antiangiogenic agent-targeted cancer treatment) or common (e.g. following intravenous bisphosphonate for cancer treatment). MRONJ is associated with significant morbidity, adversely affects quality of life (QoL), and is challenging to treat. To assess the effects of interventions versus no treatment, placebo, or an active control for the prophylaxis of MRONJ in people exposed to antiresorptive or antiangiogenic drugs.To assess the effects of non-surgical or surgical interventions (either singly or in combination) versus no treatment, placebo, or an active control for the treatment of people with manifest MRONJ. Cochrane Oral Health's Information Specialist searched the following databases: Cochrane Oral Health's Trials Register (to 23 November 2016), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, 2016, Issue 10), MEDLINE Ovid (1946 to 23 November 2016), and Embase Ovid (23 May 2016 to 23 November 2016). The US National Institutes of Health Trials Registry (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform were searched for ongoing trials. No restrictions were placed on language or publication status when searching the electronic databases; however, the search of Embase was restricted to the last six months due to the Cochrane Embase Project to identify all clinical trials and add them to CENTRAL. We included randomised controlled

  6. Myxoma of the Left Ventricle

    Science.gov (United States)

    Novoa, José; Delgado, Antonio; Alonso, Ana

    2014-01-01

    This report concerns a 69-year-old woman who presented with an asymptomatic myxoma in the left ventricle. The tumor was successfully excised. We provide a very brief review of 72 other published cases of surgically treated left ventricular myxoma. PMID:25120392

  7. Left ventricular hypertrophy in athletes.

    Science.gov (United States)

    Douglas, P S; O'Toole, M L; Katz, S E; Ginsburg, G S; Hiller, W D; Laird, R H

    1997-11-15

    Left ventricular wall thickness >1.3 cm, septal-to-posterior wall ratios > 1.5, diastolic left ventricular size >6.0 cm, and eccentric or concentric remodeling are rare in athletes. Values outside of these cutoffs in an athlete of any age probably represent a pathologic state.

  8. The Left-Handed Writer.

    Science.gov (United States)

    Bloodsworth, James Gaston

    Contrary to the beliefs of many, right-handedness is not a single factor existing in almost all people, with a few exceptions termed left-handed: neither extreme exists independently of the other. During the first 4 years of life there is a period of fluctuation between right and left-handed dominance. Statistics and findings vary in determining…

  9. Two Lefts in Latin America?

    DEFF Research Database (Denmark)

    Christensen, Steen Fryba

    In this working paper I list five researchers' categorizations of the Latin American left in power (april 2006) in a schematic form. The most important criteria for the categorizations are given.......In this working paper I list five researchers' categorizations of the Latin American left in power (april 2006) in a schematic form. The most important criteria for the categorizations are given....

  10. A Giant Left Atrial Myxoma

    Directory of Open Access Journals (Sweden)

    Medhat F. Zaher

    2014-01-01

    Full Text Available Atrial myxomas are the most common primary cardiac tumors. Patients with left atrial myxomas generally present with mechanical obstruction of blood flow, systemic embolization, and constitutional symptoms. We present a case of an unusually large left atrial myxoma discovered incidentally in a patient with longstanding dyspnea being managed as bronchial asthma.

  11. The intercrater plains of Mercury and the Moon: Their nature, origin and role in terrestrial planet evolution. Areal measurement of Mercury's first quadrant. Ph.D. Thesis

    Science.gov (United States)

    Leake, M. A.

    1982-01-01

    Various linear and areal measurements of Mercury's first quadrant which were used in geological map preparation, map analysis, and statistical surveys of crater densities are discussed. Accuracy of each method rests on the determination of the scale of the photograph, i.e., the conversion factor between distances on the planet (in km) and distances on the photograph (in cm). Measurement errors arise due to uncertainty in Mercury's radius, poor resolution, poor coverage, high Sun angle illumination in the limb regions, planetary curvature, limited precision in measuring instruments, and inaccuracies in the printed map scales. Estimates are given for these errors.

  12. Left-handedness and health

    Directory of Open Access Journals (Sweden)

    Milenković Sanja

    2010-01-01

    Full Text Available Hand dominance is defined as a proneness to use one hand rather than another in performing the majority of activities and this is the most obvious example of cerebral lateralization and an exclusive human characteristic. Left-handed people comprise 6-14% of the total population, while in Serbia, this percentage is 5-10%, moving from undeveloped to developed environments, where a socio-cultural pressure is less present. There is no agreement between investigators who in fact may be considered a left-handed person, about the percentage of left-handers in the population and about the etiology of left-handedness. In the scientific literature left-handedness has been related to health disorders (spine deformities, immunological disorders, migraine, neurosis, depressive psychosis, schizophrenia, insomnia, homosexuality, diabetes mellitus, arterial hypertension, sleep apnea, enuresis nocturna and Down Syndrome, developmental disorders (autism, dislexia and sttutering and traumatism. The most reliable scientific evidences have been published about the relationship between left-handedness and spinal deformities in school children in puberty and with traumatism in general population. The controversy of other results in up-to-now investigations of health aspects of left-handedness may partly be explained by a scientific disagreement whether writing with the left hand is a sufficient criterium for left-handedness, or is it necessary to investigate other parameters for laterality assessment. Explanation of health aspects of left-handedness is dominantly based on Geschwind-Galaburda model about 'anomalous' cerebral domination, as a consequence of hormonal disbalance. .

  13. Left ventricular wall stress compendium.

    Science.gov (United States)

    Zhong, L; Ghista, D N; Tan, R S

    2012-01-01

    Left ventricular (LV) wall stress has intrigued scientists and cardiologists since the time of Lame and Laplace in 1800s. The left ventricle is an intriguing organ structure, whose intrinsic design enables it to fill and contract. The development of wall stress is intriguing to cardiologists and biomedical engineers. The role of left ventricle wall stress in cardiac perfusion and pumping as well as in cardiac pathophysiology is a relatively unexplored phenomenon. But even for us to assess this role, we first need accurate determination of in vivo wall stress. However, at this point, 150 years after Lame estimated left ventricle wall stress using the elasticity theory, we are still in the exploratory stage of (i) developing left ventricle models that properly represent left ventricle anatomy and physiology and (ii) obtaining data on left ventricle dynamics. In this paper, we are responding to the need for a comprehensive survey of left ventricle wall stress models, their mechanics, stress computation and results. We have provided herein a compendium of major type of wall stress models: thin-wall models based on the Laplace law, thick-wall shell models, elasticity theory model, thick-wall large deformation models and finite element models. We have compared the mean stress values of these models as well as the variation of stress across the wall. All of the thin-wall and thick-wall shell models are based on idealised ellipsoidal and spherical geometries. However, the elasticity model's shape can vary through the cycle, to simulate the more ellipsoidal shape of the left ventricle in the systolic phase. The finite element models have more representative geometries, but are generally based on animal data, which limits their medical relevance. This paper can enable readers to obtain a comprehensive perspective of left ventricle wall stress models, of how to employ them to determine wall stresses, and be cognizant of the assumptions involved in the use of specific models.

  14. Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw.

    Science.gov (United States)

    Yoneda, Toshiyuki; Hagino, Hiroshi; Sugimoto, Toshitsugu; Ohta, Hiroaki; Takahashi, Shunji; Soen, Satoshi; Taguchi, Akira; Nagata, Toshihiko; Urade, Masahiro; Shibahara, Takahiko; Toyosawa, Satoru

    2017-01-01

    Antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is an intractable, though rare, complication in cancer patients with bone metastases and patients with osteoporosis who are treated with antiresorptive agents, including bisphosphonates and denosumab. Despite the more than 10 years that have passed since the first cases of bisphosphonate-related osteonecrosis of the jaw (BRONJ) were reported, our understanding of the epidemiology and pathophysiology of ARONJ remains limited, and data supported by evidence-based medicine are still sparse. However, the diagnosis and staging of ARONJ, identification of risk factors, and development of preventive and therapeutic approaches have advanced significantly over the past decade. The Position Paper 2017 is an updated version of the Position Paper 2010 of the Japanese Allied Committee on Osteonecrosis of the Jaw, which now comprises six Japanese academic societies. The Position Paper 2017 describes a new diagnostic definition for ARONJ, as proposed by the American Association of Oral and Maxillofacial Surgeons (AAOMS), summarizes our current understanding of the pathophysiology of ARONJ based on a literature search, and suggests methods for physicians and dentists/oral surgeons to manage the disease. In addition, the appropriateness of discontinuing antiresorptive medications (drug holiday) before, during, and after invasive dental treatments is discussed extensively. More importantly, the manuscript also proposes, for the first time, the importance of interactive communication and cooperation between physicians and dentists/oral surgeons for the successful treatment of ARONJ. The Position Paper 2017 is intended to serve as a guide for improving the management of ARONJ patients in Japan.

  15. 10 μ m-thick four-quadrant transmissive silicon photodiodes for beam position monitor application: electrical characterization and gamma irradiation effects

    Science.gov (United States)

    Rafí, J. M.; Pellegrini, G.; Quirion, D.; Hidalgo, S.; Godignon, P.; Matilla, O.; Juanhuix, J.; Fontserè, A.; Molas, B.; Pothin, D.; Fajardo, P.

    2017-01-01

    Silicon photodiodes are very useful devices as X-ray beam monitors in synchrotron radiation beamlines. Owing to Si absorption, devices thinner than 10 μ m are needed to achieve transmission over 90% for energies above 10 keV . In this work, new segmented four-quadrant diodes for beam alignment purposes are fabricated on both ultrathin (10 μ m-thick) and bulk silicon substrates. Four-quadrant diodes implementing different design parameters as well as auxiliary test structures (single diodes and MOS capacitors) are studied. An extensive electrical characterization, including current-voltage (I-V) and capacitance-voltage (C-V) techniques, is carried out on non-irradiated and gamma-irradiated devices up to 100 Mrad doses. Special attention is devoted to the study of radiation-induced charge build-up in diode interquadrant isolation dielectric, as well as its impact on device interquadrant resistance. Finally, the devices have been characterized with an 8 keV laboratory X-ray source at 108 ph/s and in BL13-XALOC ALBA Synchroton beamline with 1011 ph/s and energies from 6 to 16 keV . Sensitivity, spatial resolution and uniformity of the devices have been evaluated.

  16. High pregnancy rate after microsurgical tubal reanastomosis by temporary loose parallel 4-quadrant sutures technique: a long long-term follow-up report on 961 cases.

    Science.gov (United States)

    Moon, Hwa Sook; Joo, Bo Sun; Park, Gun Sik; Moon, Sung Eun; Kim, Sang Gap; Koo, Ja Seong

    2012-06-01

    Only a limited portion of sterilized women undergo tubal reanastomosis due to high costs, limited availability of qualified practitioners willing to perform the procedure and increasing success rates with IVF. However, IVF has complications and an increased risk of ectopic pregnancy and multiple pregnancies. Recently, the importance of specialized training for tubal anastomosis has been re-emphasized. This study aimed to report the procedure of our microsurgical tubal reanastomosis by a temporary loose parallel 4-quadrant suture technique and its high pregnancy outcome over the last 20 years. This clinical study retrospectively analyzed data on 961 consecutive patients who underwent tubal reversal between March 1988 and August 2007 in a large urban medical center. All surgical operations were performed by microsurgical tubal reanastomosis using a temporary loose parallel 4-quadrant suture technique by a single surgeon. Subsequent pregnancy outcomes were evaluated. The overall pregnancy rate was 85.1, 82.6 being intrauterine and 2.5% ectopic. The pregnancy rate was significantly reduced in patients over 40 years old (53.9%) compared with patients aged 40 years or less (90.3%) (P technique resulted in a high pregnancy rate comparable with the level of natural fertility. The study also reveals that ectopic pregnancy frequently occurs in tubal reanastomosis of the interstitial-ampulla site compared with other sites.

  17. Study of Power Converter Topologies with Energy Recovery and grid power flow control. Part A: 2-quadrant converter with energy storage.

    CERN Document Server

    Maestri, S; Uicich, G; Benedetti, M; Le Godec, G; Papastergiou, K

    2015-01-01

    In the framework of a Transfer line (TT2) Consolidation Programme, a number of studies on Energy cycling have been commissioned. Part of this work involves the study of different power electronic system topologies for magnet energy recovery [1{5]. In this report, the use of a two-quadrant (2Q) regulator connected to the DC link of a 4-quadrant magnet supply is analysed. The key objective of the study is to find control strategies that result in the control of the peak power required from the power network as well as to recover the magnet energy into capacitor banks with controlled voltage fluctuation. The study comprises the modelling of the system by means of the method of state averaging and the development of regulation strategies to energy management. The proposed control strategies can be divided in two groups: in the first group, the magnet current is used to dene the reference for the control system, while in the second group this current is considered as a perturbation and some strategies are devised ...

  18. Jaw-opening reflex and corticobulbar motor excitability changes during quiet sleep in non-human primates

    DEFF Research Database (Denmark)

    Yao, Dongyuan; Lavigne, Gilles J.; Lee, Jye-Chang

    2013-01-01

    and corticobulbar motor excitability of jaw muscles was determined during the quiet awake state (QW) and quiet sleep (QS) in monkeys (n = 4). Measurements and Results: During QS sleep, compared to QW periods, both tongue stimulation-evoked jaw-opening reflex peak and root mean square amplitudes were significantly......Study Objective: To test the hypothesis that the reflex and corticobulbar motor excitability of jaw muscles is reduced during sleep. Design: Polysomnographic recordings in the electrophysiological study. Setting: University sleep research laboratories. Participants and Interventions: The reflex...... decreased with stimulations at 2-3.5 × thresholds (P sleep was also significantly longer than during QW. Intracortical microstimulation (ICMS) within the cortical masticatory area induced rhythmic jaw movements at a stable threshold (≤ 60 μA) during QW...

  19. Administration of teriparatide improves the symptoms of advanced bisphosphonate-related osteonecrosis of the jaw: preliminary findings.

    Science.gov (United States)

    Kakehashi, H; Ando, T; Minamizato, T; Nakatani, Y; Kawasaki, T; Ikeda, H; Kuroshima, S; Kawakami, A; Asahina, I

    2015-12-01

    Teriparatide is a synthetic polypeptide hormone that contains the 1-34 amino acid fragment of the recombinant human parathyroid hormone that stimulates bone formation. Currently, it is approved only for the treatment of osteoporosis. The outcomes of daily teriparatide injections for the treatment of bisphosphonate-related osteonecrosis of the jaw in 10 patients are reported here. Two of the 10 cases dropped out due to adverse events. Of the remaining eight cases, seven exhibited clinical improvement of the jaw-related symptoms of osteonecrosis and progression of the sequestration, while one case did not show improvement of the symptoms. Administration of teriparatide in patients with osteonecrosis of the jaw promotes bone formation and subsequent sequestration over a short period of time. These results suggest that adjunctive teriparatide therapy is a viable and effective option for treating osteonecrosis of the jaw. Copyright © 2015 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  20. Dental evaluation of scuba diving mouthpieces using a subject assessment index and radiological analysis of jaw position

    Science.gov (United States)

    Hobson, R; Newton, J

    2001-01-01

    Objective—To compare two experimental scuba mouthpieces with a commercially available design. Methods—A laboratory study using six men to assess effort, muscle pain, muscle fatigue, facial discomfort, tooth discomfort, and loss of lip sensation using a visual analogue scale. Cephalometric radiographs and analysis of jaw position with each mouth piece were also used. Results—Fully customised mouthpieces caused the least discomfort, muscle pain, fatigue, and effort. They also resulted in the least mandibular displacement from the resting position. Radiographic analysis of jaw position showed that the fully customised design resulted in the least displacement from normal jaw position. Conclusions—A fully customised design gives the greatest comfort, least effort, and least mandibular displacement. This design is recommended, particularly for divers who experience temporomandibular dysfunction associated with diving. Key Words: scuba diving; temporomandibular dysfunction; mouthpieces; teeth; jaw PMID:11273967

  1. Application of IMF screws to assist internal rigid fixation of jaw fractures: our experiences of 168 cases.

    Science.gov (United States)

    Bai, Zhenxi; Gao, Zhibiao; Xiao, Xia; Zhang, Wenjuan; Fan, Xing; Wang, Zhaoling

    2015-01-01

    Intermaxillary fixation (IMF) screws were first introduced to achieve IMF as a kind of bone borne appliance for jaw fractures in 1989. Because this method can overcome many disadvantages associated with tooth borne appliance, IMF screws have been popularly used for jaw fractures since then. From March 2011 to February 2014, we treated 168 cases with single or multiple jaw fractures by open reduction and a total of 705 IMF screws were intraoperatively applied in all the cases to achieve IMF and maintain dental occlusion as an adjuvant to open reduction. The numbers, implantation sites and complications of IMF screws were retrospectively analyzed. In our experience, we found that IMF screws were important to assist open reduction of jaw fractures but their roles should be objectively assessed and the reliability of open reduction and internal rigid fixation must be emphasized. Much attention should be paid when implanting.

  2. Extracting DNA from 'jaws': High yield and quality from archived tiger shark (Galeocerdo cuvier) skeletal material

    DEFF Research Database (Denmark)

    Eg Nielsen, Einar; Morgan, J. A T; Maher, S. L.

    2017-01-01

    archived skeletal material from sharks as a source of DNA for temporal genomic studies. Six different methods for DNA extraction, encompassing two different commercial kits and three different protocols, were applied to material, so-called bio-swarf, from contemporary and archived jaws and vertebrae...... of tiger sharks (Galeocerdo cuvier). Protocols were compared for DNA yield and quality using a qPCR approach. For jaw swarf, all methods provided relatively high DNA yield and quality, while large differences in yield between protocols were observed for vertebrae. Similar results were obtained from samples...... of white shark (Carcharodon carcharias). Application of the optimized methods to 38 museum and private angler trophy specimens dating back to 1912 yielded sufficient DNA for downstream genomic analysis for 68% of the samples. No clear relationships between age of samples, DNA quality and quantity were...

  3. Ossifying fibroma of the jaws: report of two cases and literature review.

    Science.gov (United States)

    Gondivkar, Shailesh M; Gadbail, Amol R; Chole, Revant; Parikh, Rima V; Balsaraf, Swati

    2011-09-01

    Ossifying fibromas are uncommon benign tumors of the craniofacial skeleton thought to originate from the periodontal ligament. Most are small and incidentally diagnosed with routine dental radiographs. With larger lesions, patients may complain of an abnormal bite or an enlarging mass. This tumor involves slow-evolving growth with deforming swelling generally arising in the mandible, with possible early tooth displacement. From the radiological perspective, more than 50% of the lesions exhibit an expansion of the jaws and 53% shows well-defined unilocular radiolucencies and 40% are mixed radiolucent-radiopaque lesions. The lesions exceptionally can be radiopaque. Ossifying fibroma presents several variant histopathological subtypes. The overlapping clinical and histopathological features of these subtypes have led to diagnostic dilemma and confusion. Complete excision of this tumor has become a necessity since it is notorious for recurrence. We present here two cases of ossifying fibroma of the jaws along with insight into the literature review. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. Complex Sensory Corpuscles in the Upper Jaw of Horsfield’s Tortoise (Testudo horsfieldii

    Directory of Open Access Journals (Sweden)

    Marcela Buchtová

    2009-01-01

    Full Text Available The sensory corpuscles of Testudo horsfieldii in the skin of the upper lip and face were studied with light and electron microscopy. The sensory corpuscles were situated under epidermis; in the corium and also between the upper jaw bone tissues in the rostral part of oral cavity. The skin sensory corpuscles with a ramified inner core were grouped in clusters. Within the corpuscle there were several simple inner cores embedded within a common superficial capsule. The complex corpuscles have a novel structure in comparison to what has been described for sensory nerve endings in turtle. The complex sensory corpuscles probably function as mechanoreceptors important for monitoring the movement of the keratinized ridges and the most rostral part of the upper jaw, the rhamphotheci.

  5. [Acupuncture combined with magnetic therapy for treatment of temple-jaw joint dysfunction].

    Science.gov (United States)

    Wang, Xiao-Hui; Zhang, Wen

    2009-04-01

    To compare clinical therapeutic effects of acupuncture combined with magnetic therapy and simple magnetic therapy on temple-jaw joint dysfunction. Eighty-two cases were randomly divided into an observation group (n = 52) and a control group (n = 30). The observation group was treated with acupuncture at Xiaguan (ST 7), Jiache (ST 6), Hegu (LI 4), etc. and AL-2 low frequency electromagnetic comprehensive treatment instrument; the control group was treated with AL-2 low frequency electromagnetic comprehensive treatment instrument. The cured and markedly effective rate of 90.4% in the observation group was significantly better than 66.7% in the control group (P magnetic therapy is significantly better than that of the simple magnetic therapy on temple-jaw joint dysfunction.

  6. Testosterone, anastrozole, factor V Leiden heterozygosity and osteonecrosis of the jaws.

    Science.gov (United States)

    Pandit, Ramesh S; Glueck, Charles J

    2014-04-01

    Our specific aim is to describe the development of thrombotic osteonecrosis of the jaws after testosterone-anastrozole therapy in a 55-year-old white man subsequently found to have previously undiagnosed factor V Leiden heterozygosity. Before the diagnosis of V Leiden heterozygosity, he was given testosterone gel, 50 mg/day, and on testosterone, serum testosterone (963 ng/dl) and estradiol were high (50 pg/ml). Anastrozole was started, and testosterone was continued. Six months later, osteonecrosis of the jaws was diagnosed. Exogenous testosterone is aromatized to estradiol and estradiol-induced thrombophilia, when superimposed on underlying familial thrombophilia, as in this case, may lead to thrombosis and osteonecrosis. We recommend that before giving testosterone, at a minimum, screening for the factor V Leiden and G20210A mutations, and factor VIII and XI activity be carried out, to avoid unanticipated thrombosis.

  7. Autosomal dominant type of endosteal hyperostosis with unusual manifestations of sclerosis of the jaw bones

    International Nuclear Information System (INIS)

    Nakamura, Takashi; Yamada, Naoyuki; Nonaka, Ryosuke; Sasaki, Motomasa

    1987-01-01

    We report three cases of autosomal dominant type endosteal hyperostosis which occurred in one Japanese family. A new pattern of sclerotic changes in the jaw bones is evident. In all members of the family there was a symmetrical thickening of the diaphyseal cortices of the long bones. The affected bones were only minimally widened and the epiphyses and metaphyses were spared. Endosteal sclerosis of the neurocranium was present with loss of the diploe. The sclerotic changes included enlargement and mottled sclerosis of both the maxilla and mandible, with multiple embedded teeth and odontomas. The ramus of the mandible was spared. Severe sclerosis of the jaw bones was present only in a 28-year-old women. The 2-year-son showed only focal sclerosis in the mandible, and his grandmother had minimal changes in the skeleton. (orig.)

  8. Epidemiology and risk factors for osteonecrosis of the jaw in cancer patients.

    Science.gov (United States)

    Hoff, Ana O; Toth, Bela; Hu, Mimi; Hortobagyi, Gabriel N; Gagel, Robert F

    2011-02-01

    Osteonecrosis of the jaw (ONJ), previously an entity associated with radiation therapy to the head and neck, has been observed in patients treated with bisphosphonates. Patients with metastatic breast cancer and myelomatous bone disease, commonly treated with high-potency nitrogen-containing bisphosphonates for a prolonged period of time, have the greatest risk of ONJ development. The reported frequency of ONJ ranges from 0.6% to 6.2% in breast cancer and from 1.7% to 15% in patients with multiple myeloma. Osteonecrosis of the jaw has also been observed in patients with other cancers such as prostate cancer and in benign bone disorders such as osteoporosis and Paget's disease in which the incidence is low. Risk factors associated with the development of ONJ include dental extractions, length of bisphosphonate treatment, and the type of bisphosphonate used. In this review, we summarize the reported incidence and risk factors associated with ONJ. © 2010 New York Academy of Sciences.

  9. Osteonecrosis of the jaw and bisphosphonate use in breast cancer patients.

    Science.gov (United States)

    Kyrgidis, Athanassios; Triaridis, Stefanos; Vahtsevanos, Kostantinos; Antoniades, Kostantinos

    2009-08-01

    It is renowned that breast cancer patients suffer from a number of cancer-related skeletal events, while drugs recently added to the practitioners' quiver, such as aromatase inhibitors, intensify the need to preserve bone mass in this group of patients. Bisphosphonates are potent inhibitors of both normal and pathologic bone resorption. Besides their apoptotic and antiproliferative activity on osteoclasts, bisphosphonates can also exert various effects on macrophages, keratinocytes and fibroblasts. Bisphosphonate-related osteonecrosis of the jaw is a complication that emerged after broad clinical use of bisphosphonates, and which has not yet been adequately described in a clinical trial setting. The purpose of this review is to critically reflect the incidence, etiopathogenesis, prevention and treatment of osteonecrosis of the jaw. Succinct suggestions are provided to ensure clinicians prevent and detect the complications early.

  10. Actinomyces israelii in osteoradionecrosis of the jaws. Histopathologic and immunocytochemical study of five cases

    International Nuclear Information System (INIS)

    Happonen, R.P.; Viander, M.; Pelliniemi, L.; Aitasalo, K.

    1983-01-01

    Five surgically treated patients with osteoradionecrosis of the jaws are presented. The clinical history of the disease varied from 3 to 17 years. In three cases the progression of the disease was enhanced by surgical procedures performed in the irradiated area causing exfoliation of the premaxillary area in one case and spontaneous mandibular fracture in two cases. Actinomyces israelii was demonstrated in tissue sections of all five cases by using FITC-labeled specific antiserum and additionally with peroxidase-antiperoxidase method in one case. Candida was found in histologic sections of three cases. Radiation damage in the oral soft tissues and jawbones makes the atmosphere favorable for anaerobic microorganisms. The present results indicate that the role of A. israelii in the pathogenesis of osteoradionecrosis of the jaws has not been fully appreciated

  11. IMPACT OF ROCK HARDNESS ON FRAGMENTATION BY HYDRAULIC HAMMER AND CRUSHING IN JAW CRUSHER

    Directory of Open Access Journals (Sweden)

    Trpimir Kujundžić

    2008-12-01

    Full Text Available The physical and mechanical characteristics of intact rocks depend on the way of their formation, sustained deformations and the process of wearing a specific rock has been exposed to. These characteristics have a rather high influence on the technological process of extraction and dressing of mineral raw materials. However, the mechanical characteristics of rocks due to use of explosives for their extraction in the open pit have a more significant impact. The rock blocks extracted by blasting which are larger than the opening of the primary crusher are usually fragmented by hydraulic hammer. The paper presents the results of the testing of impact of rock hardness on fragmentation of rocks by means of hydraulic hammer and during crushing in jaw crusher. The testing was carried out on the rock samples from five quarries. According to the obtained results the hardness has a considerably larger impact on the fragmentation energy by hydraulic hammer than on the crushing energy in jaw crusher.

  12. Comparison of jaw muscle EMG activity in awake and sleep bruxers

    DEFF Research Database (Denmark)

    Castrillon, Eduardo; Dreyer Nielsen, Patricia; Haugland, Morten

    2015-01-01

    TITLE: Comparison of Jaw Muscle EMG Activity in Awake and Sleep Bruxers AUTHORS: E. E. Castrillon, P. Dreyer, M. Haugland, W. Yachida, T. Arima, P. Svensson AUTHORS/INSTITUTIONS: E.E. Castrillon, P. Dreyer, P. Svensson, Aarhus School of Dentistry, Aarhus C, DENMARK; E.E. Castrillon, P. Svensson, ...... of the jaw muscle activity in different populations of self-reported bruxers and non-bruxers. Financial Interest Disclosure: Morten Haughland works for DELTA A/S that has commercial agreement with SUNSTAR that produces Grindcare (portable EMG device)...... been proposed to have different underlying pathophysiology. Objectives: To compare the characteristics of multiple days EMG assessment of the anterior temporalis muscles between patients with self-reported awake bruxism, sleep bruxism and healthy individuals. Methods: Methods: Participants...

  13. Hyperparathyroidism-jaw Tumor Syndrome: An Overlooked Cause of Severe Hypercalcemia.

    Science.gov (United States)

    Mathews, Joseph Wolfgang; Winchester, Rhonda; Alsaygh, Nebras; Bartlett, Anne M; Luttrell, Louis

    2016-09-01

    Ossifying fibromas of the maxillofacial bones are an uncommon form of benign neoplasm usually treated by surgical excision. Up to 30% of patients with hyperparathyroidism-jaw tumor syndrome, a rare form of multiple endocrine neoplasia resulting from autosomal dominant inactivating mutation of the Hrpt2 tumor suppressor gene, initially present with ossifying fibromas. Coincident hypercalcemia because of the presence of parathyroid adenoma is common in these patients, of whom 15% may have or may develop parathyroid carcinoma. The authors present a case of severe postsurgical hypercalcemia after removal of a large maxillary ossifying fibroma in a patient with previously unrecognized hyperparathyroidism-jaw tumor AU3 syndrome. Copyright © 2016 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  14. Osteonecrosis of the jaw: a rare and devastating side effect of bisphosphonates.

    LENUS (Irish Health Repository)

    Ryan, P

    2009-12-01

    Evidence has emerged that bisphosphonate use in cancer patients is associated with osteonecrosis of the jaw. This form of osteonecrosis has been termed bisphosphonate induced osteonecrosis of the jaw (BIONJ). BIONJ is commonly precipitated by a tooth extraction in patients treated with long term, potent, high dose intravenous bisphosphonates for the management of myeloma, breast or prostate cancer. The overall prevalence of BIONJ is about 5% in patients with these malignancies. Current evidence shows that the risk of BIONJ in non-cancerous patients, such as those with osteoporosis, is very low and appears to be comparable with that of the general population. Prescribing physicians need to encourage cancer patients to see their dentists before the initiation of bisphosphonate treatment, and regularly thereafter.

  15. Phasic bursts of the antagonistic jaw muscles during REM sleep mimic a coordinated motor pattern during mastication.

    Science.gov (United States)

    Kato, T; Nakamura, N; Masuda, Y; Yoshida, A; Morimoto, T; Yamamura, K; Yamashita, S; Sato, F

    2013-02-01

    Sleep-related movement disorders are characterized by the specific phenotypes of muscle activities and movements during sleep. However, the state-specific characteristics of muscle bursts and movement during sleep are poorly understood. In this study, jaw-closing and -opening muscle electromyographic (EMG) activities and jaw movements were quantified to characterize phenotypes of motor patterns during sleep in freely moving and head-restrained guinea pigs. During non-rapid eye movement (NREM) sleep, both muscles were irregularly activated in terms of duration, activity, and intervals. During rapid eye movement (REM) sleep, clusters of phasic bursts occurred in the two muscles. Compared with NREM sleep, burst duration, activity, and intervals were less variable during REM sleep for both muscles. Although burst activity was lower during the two sleep states than during chewing, burst duration and intervals during REM sleep were distributed within a similar range to those during chewing. A trigger-averaged analysis of muscle bursts revealed that the temporal association between the bursts of the jaw-closing and -opening muscles during REM sleep was analogous to the temporal association during natural chewing. The burst characteristics of the two muscles reflected irregular patterns of jaw movements during NREM sleep and repetitive alternating bilateral movements during REM sleep. The distinct patterns of jaw muscle bursts and movements reflect state-specific regulations of the jaw motor system during sleep states. Phasic activations in the antagonistic jaw muscles during REM sleep are regulated, at least in part, by the neural networks involving masticatory pattern generation, demonstrating that waking jaw motor patterns are replayed during sleep periods.

  16. Bisphosphonate-related osteonecrosis of the jaw in metastatic breast cancer patients: a review of 25 cases

    OpenAIRE

    Kim, Hong-Joon; Park, Tae-Jun; Ahn, Kang-Min

    2016-01-01

    Background Intravenous bisphosphonates have been used in metastatic breast cancer patients to reduce pathologic bone fracture and bone pain. However, necrosis of the jaw has been reported in those who received intravenous bisphosphonates. Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is caused by dental extraction, dental implant surgery, and denture wearing; however, it occurs spontaneously. The purpose of this study was to report BRONJ in metastatic breast cancer patients. Methods...

  17. Left main percutaneous coronary intervention.

    Science.gov (United States)

    Teirstein, Paul S; Price, Matthew J

    2012-10-23

    The introduction of drug-eluting stents and advances in catheter techniques have led to increasing acceptance of percutaneous coronary intervention (PCI) as a viable alternative to coronary artery bypass graft (CABG) for unprotected left main disease. Current guidelines state that it is reasonable to consider unprotected left main PCI in patients with low to intermediate anatomic complexity who are at increased surgical risk. Data from randomized trials involving patients who are candidates for either treatment strategy provide novel insight into the relative safety and efficacy of PCI for this lesion subset. Herein, we review the current data comparing PCI with CABG for left main disease, summarize recent guideline recommendations, and provide an update on technical considerations that may optimize clinical outcomes in left main PCI. Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  18. Left bundle-branch block

    DEFF Research Database (Denmark)

    Risum, Niels; Strauss, David; Sogaard, Peter

    2013-01-01

    The relationship between myocardial electrical activation by electrocardiogram (ECG) and mechanical contraction by echocardiography in left bundle-branch block (LBBB) has never been clearly demonstrated. New strict criteria for LBBB based on a fundamental understanding of physiology have recently...

  19. Dabigatran for left ventricular thrombus

    Directory of Open Access Journals (Sweden)

    Satishkumar Kolekar

    2015-09-01

    Dabigatran is a reversible direct thrombin inhibitor and currently approved for the prevention of thromboembolic episodes in non-valvar atrial fibrillation. This case demonstrates possible thrombolytic properties of dabigatran in resolution of left ventricular thrombus.

  20. Apraxia in left-handers.

    Science.gov (United States)

    Goldenberg, Georg

    2013-08-01

    In typical right-handed patients both apraxia and aphasia are caused by damage to the left hemisphere, which also controls the dominant right hand. In left-handed subjects the lateralities of language and of control of the dominant hand can dissociate. This permits disentangling the association of apraxia with aphasia from that with handedness. Pantomime of tool use, actual tool use and imitation of meaningless hand and finger postures were examined in 50 consecutive left-handed subjects with unilateral hemisphere lesions. There were three aphasic patients with pervasive apraxia caused by left-sided lesions. As the dominant hand is controlled by the right hemisphere, they constitute dissociations of apraxia from handedness. Conversely there were also three patients with pervasive apraxia caused by right brain lesions without aphasia. They constitute dissociations of apraxia from aphasia. Across the whole group of patients dissociations from handedness and from aphasia were observed for all manifestations of apraxia, but their frequency depended on the type of apraxia. Defective pantomime and defective tool use occurred rarely without aphasia, whereas defective imitation of hand, but not finger, postures was more frequent after right than left brain damage. The higher incidence of defective imitation of hand postures in right brain damage was mainly due to patients who had also hemi-neglect. This interaction alerts to the possibility that the association of right hemisphere damage with apraxia has to do with spatial aptitudes of the right hemisphere rather than with its control of the dominant left hand. Comparison with data from right-handed patients showed no differences between the severity of apraxia for imitation of hand or finger postures, but impairment on pantomime of tool use was milder in apraxic left-handers than in apraxic right-handers. This alleviation of the severity of apraxia corresponded with a similar alleviation of the severity of aphasia as

  1. Left ventricular apical ballooning syndrome

    International Nuclear Information System (INIS)

    Rahman, N.; Tai, J.; Soofi, A.

    2007-01-01

    The transient left ventricular apical ballooning syndrome, also known as Takotsubo cardiomyopathy, is characterized by transient left ventricular dysfunction in the absence of obstructive epicardial coronary disease. Although the syndrome has been reported in Japan since 1990, it is rare in other regions. Rapid recognition of the syndrome can modify the diagnostic and therapeutic attitude i.e. avoiding thrombolysis and performing catheterization in the acute phase. (author)

  2. Dental extraction following zoledronate, induces osteonecrosis in rat?s jaw

    OpenAIRE

    Vidal-Guti?rrez, Ximena; G?mez-Clavel, Jos?-Francisco; Gait?n-Cepeda, Luis-Alberto

    2017-01-01

    Background Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is clinically characterized by the presence of exposed bone in the oral cavity that persists for more than eight weeks. Previous attempts to establish an animal model have not sufficiently considered disease features. Our aim was to establish an inexpensive and replicable animal model that develops BRONJ in a short time. Material and Methods Thirty-two male Wistar rats were randomly divided into two groups: control and experim...

  3. Myoelectric manifestations of jaw elevator muscle fatigue and recovery in healthy and TMD subjects.

    Science.gov (United States)

    Castroflorio, T; Falla, D; Tartaglia, G M; Sforza, C; Deregibus, A

    2012-09-01

    The effects of muscle pain and fatigue on the control of jaw elevator muscles are not well known. Furthermore, the myoelectric manifestations of fatigue and recovery from fatigue in the masticatory muscles are not reported in literature. The main aims of this study were (i) to evaluate the possible use of surface electromyography (sEMG) as an objective measure of fatigue of the jaw elevator muscles, (ii) to compare the myoelectric manifestations of fatigue in the temporalis anterior and masseter muscles bilaterally, (iii) to assess recovery of the investigated muscles after an endurance test and (iv) to compare fatigue and recovery of the jaw elevator muscles in healthy subjects and patients with muscle-related temporomandibular disorders (TMD). The study was performed on twenty healthy volunteers and eighteen patients with muscle-related TMD. An intra-oral compressive-force sensor was used to measure the voluntary contraction forces close to the intercuspal position and to provide visual feedback of submaximal forces to the subject. Surface EMG signals were recorded with linear electrode arrays during isometric contractions at 20%, 40%, 60% and 80% of the maximum voluntary contraction force, during an endurance test and during the recovery phase. The results showed that (i) the slope of the mean power spectral frequency (MNF) and the initial average rectified value (ARV) could be used to monitor fatigue of the jaw elevators, (ii) the temporalis anterior and masseter muscle show the same myoelectric manifestations of fatigue and recovery and (iii) the initial values of MNF and ARV were lower in patients with muscle-related TMD. The assessment of myoelectric manifestations of fatigue in the masticatory muscles may assist in the clinical assessment of TMDs. © 2012 Blackwell Publishing Ltd.

  4. Jaw Intraosseous Lesions Biopsied Extracted From 1998 to 2010 in an Iranian Population.

    Science.gov (United States)

    Jamshidi, Shokoofeh; Shojaei, Setareh; Roshanaei, Ghodratollah; Modabbernia, Shirin; Bakhtiary, Esmaeel

    2015-06-01

    Jaw bones might be potential locations for different lesions. Differences in prevalence and the type of lesions can help in designing and programming prevention procedures in health care centers. The aim of the present study was to evaluate the prevalence of intraosseous lesions in the jaws of patients referred to diagnostic and therapeutic centers in Hamadan during 1990-2010. This cross-sectional descriptive analytical study was carried out in Hamadan in 2011. Data sheets of the subjects were used to collect all the data of patients with intraosseous lesions, including their age, gender, location of the lesion, the radiographic view of lesions, and their type and histopathological diagnoses. Data were analyzed with SPSS, using means and frequencies. A total of 284 intraosseous lesions were reported in our study. The mean age of the subjects was 28.8 ± 15.2 years. The lesions were distributed in males and females almost similarly. The most prevalent lesions were cystic lesions (54.58%), manifestations of systemic conditions in jaw bones (18.3%), benign tumors (15.5%), malignant lesions (6.7%), and inflammatory lesions (4.92%), in a descending order. The most common cystic lesion was radicular cyst; the most common manifestation of systemic conditions in jaw bones was central giant cell granuloma; the most common benign tumor was ameloblastoma; the most common malignant lesion was osteosarcoma; and the most common inflammatory lesion was periapical granuloma. Our data provided information on the prevalence and types of intraosseous lesions among an Iranian population. This study provided baseline information to help in designing and programming procedures in health care centers in every community so that preventive therapeutic measures can be adopted.

  5. Tru-Cut and Fine Needle Aspiration Biopsy Diagnosis of Lesions of the Jaws

    OpenAIRE

    AYHAN, Namık Kemal; KESKİN, Cengizhan; OLGAC, Vakur

    2014-01-01

    Nowadays, modern biopsy techniques such as fine and wide needles are used instead of invasive biopsy techniques for examining malign and benign lesions. This study examines whether wide needle biopsy (Tru-cut) possesses advantages as an alternative method to open biopsy. This study was performed on 40 patients with suspicious intra-jaw lesions. An 18-gauge, three-piece biopsy device was used. All the samples were sent to the tumor pathology unit at the oncology institute for histopathologi...

  6. The pathology of head and neck tumors: cysts of the jaws, part 12.

    Science.gov (United States)

    Regezi, J A; Courtney, R M; Batsakis, J G

    1981-01-01

    The jaws are unique bones of the skeleton because of their intimate involvement with tooth and facial development. Abnormal sequelae of these developmental processes may give rise to cystic lesions later in life. This paper reviews the pathogenesis, clinical features, and behavior of these odontogenic and nonodontogenic cysts. Justification is found for the exclusion of the globulomaxillary, midmandibular, and midpalatine cysts from a current classification. Emphasis is placed on the importance and controversy surrounding the odontogenic keratocyst.

  7. Stress assessment using hair cortisol of kangaroos affected by the lumpy jaw disease

    OpenAIRE

    SOTOHIRA, Yukari; SUZUKI, Kazuyuki; SANO, Tadashi; ARAI, Chigusa; ASAKAWA, Mitsuhiko; HAYASHI, Hideaki

    2017-01-01

    The aim of this study was to objectively assess stress of kangaroos affected by lumpy jaw disease (LJD) using plasma and hair cortisol concentrations. The plasma and hair samples were collected from kangaroos with LJD and healthy controls. Collected hair samples were extracted with methanol after washing with isopropanol, following which they were processed with the cortisol enzyme immunoassay kit. The plasma cortisol concentration of LJD animals tended to be higher than that of the control. ...

  8. Bisphosphonate-associated osteonecrosis of the jaw in breast cancer patients: recommendations for prevention and treatment.

    Science.gov (United States)

    Fehm, T; Felsenberg, D; Krimmel, M; Solomayer, E; Wallwiener, D; Hadjii, P

    2009-08-01

    Osteonecrosis of the jaw (ONJ) is a rare but severe disease which has been diagnosed in women with breast cancer on a bisphosphonate (BP) therapy. Thus, the German society of senology appointed a multidisciplinary task force to establish a consensus on the use of bisphosphonates in breast cancer patients with bone metastases, considering in particular the possible risk of ONJ. This report summarizes the results and recommendations for the prevention and treatment of ONJ in breast cancer patients receiving BP.

  9. The phenomenon of osteonecrosis of the jaw in patients with metastatic breast cancer.

    Science.gov (United States)

    Van Poznak, Catherine

    2006-02-01

    Osteonecrosis of the jaw (ONJ) has been noted to occur in patients with cancer receiving bisphosphonate therapy and may also be referred to as bisphosphonate associated osteonecrosis (BON). ONJ has come to attention through case reporting and the pathogenesis and true incidence of this condition are not yet defined. ONJ appears to be a relatively uncommon event, but it is of clinical significance; the evolving data on ONJ are discussed here.

  10. Bisphosphonate induced osteonecrosis of jaw in breast cancer patients: A systematic review

    OpenAIRE

    Varun, BR; Sivakumar, TT; Nair, Bindu J; Joseph, Anna P

    2012-01-01

    Background: Bisphosphonate therapy is widely used for the treatment of bone metastasis in breast cancer patients. Aim: The aim of this study is to estimate the overall prevalence of bisphosphonate induced osteonecrosis of jaw (BONJ) in breast cancer patients with bone metastasis. Materials and Methods: A literature review was conducted to search and evaluate all the articles that contained original data on the prevalence of BONJ in breast cancer patients from the year 2003-2009. Pubmed search...

  11. Effect of antiresorptive drugs on bony turnover in the jaw: denosumab compared with bisphosphonates.

    Science.gov (United States)

    Ristow, Oliver; Gerngroß, Carlos; Schwaiger, Markus; Hohlweg-Majert, Bettina; Kehl, Victoria; Jansen, Heike; Hahnefeld, Lilian; Koerdt, Steffen; Otto, Sven; Pautke, Christoph

    2014-04-01

    Osteonecrosis of the jaw as a result of treatment with receptor activators of nuclear factor kappa-B ligand (RANKL) inhibitors (denosumab) is a new type of bony necrosis, the exact pathogenesis of which is unknown. Our aim was to find out whether the turnover of bone in the jaw is increased after denosumab has been given compared with other skeletal sites, and if that turnover might have a role in denosumab-related osteonecrosis of the jaw (DRONJ). Bone scintigraphic images of 45 female patients with breast cancer and bone metastases were analysed retrospectively, and divided into 3 groups: those given denosumab, those given a bisphosphonate, and a control group (n=15 in each). All patients had bone scintigraphy before treatment (T0) and during the course of treatment after 12 (T1) and 24 (T2) months. The data were analysed quantitatively using 6 preset bony regions of interest. There was similar turnover of bone in the mandible compared with other skeletal sites (such as the femur), while the maxilla showed significantly higher turnover. None of the bony regions investigated showed any significant changes after the bisphosphonate had been given. There was a tendency to increase bone turnover in those patients taking denosumab. The bone turnover of the jawbone is not overtly changed either by a bisphosphonate or denosumab, so it seems unlikely that oversuppression of bony turnover in the jawbones plays an important part either in the pathogenesis of DRONJ or in the bisphosphonate-related osteonecrosis of the jaw (BRONJ). Copyright © 2014 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  12. The Challenge Treatment of Medication Related Osteonecrosis of the Jaw: A Case Report

    OpenAIRE

    M Rodríguez Sánchez; Bassi AP; Carvalho PS

    2015-01-01

    Bisphosphonates toxicological effect on alveolar bone could be associated to medication related osteonecrosis of the jaw. (MRONJ) Oral surgical procedures as; tooth extractions, implants placements or trauma are suggested risk factors. The aim of this paper is to describe a case of MRONJ and recurrence after the first right mandibular molar extraction. A 54 years old man was referred to the Department of Surgery and Integrated Clinic of Aracatuba Dental School, Univ. Estadual Paulista - UNESP...

  13. JAWS: Just Add Water System - A device for detection of nucleic acids in Martian ice caps

    DEFF Research Database (Denmark)

    Hansen, Anders J.; Willerslev, Eske; Mørk, Søren

    2002-01-01

    with a regulation of pH and salt concentrations e.g. the MOD systems and could be installed on a planetary probe melting its way down the Martian ice caps e.g. the NASA Cryobot. JAWS can be used for detection of remains of ancient life preserved in the Martian ice as well as for detection of contamination brought...... to the planet from Earth....

  14. Retrospective analysis of jaw biopsies in young adults. A study of 1599 cases in Southern Brazil

    Science.gov (United States)

    Alves, Alessandro; Correa, Marcos; Etges, Adriana; Vasconcelos, Ana-Carolina; Gomes, Ana-Paula; Tarquinio, Sandra

    2017-01-01

    Background To evaluate the prevalence and the characteristics of jaw lesions diagnosed in young adults aged 20 to 30 years in a southern Brazil reference center, over a period of 25 years. And to analyze the concordance between clinical and histological diagnosis. Material and Methods In this cross-sectional retrospective study, the biopsies files from this center were retrieved and data regarding sex, age, bone localization, clinical and histological diagnosis were collected. The histological diagnosis were grouped into the categories Cystic lesions of odontogenic origin, Periapical inflammation, Odontogenic tumors, Bone diseases, Health tissue and Nonspecific diagnostic. Absolute and relative frequencies were estimated with descriptive analysis. The agreement between clinical and histological diagnosis was measured through Kappa statistic. Results A total of 18,181 histopathological analysis were performed during the period of the study, registering 1,599 jaw lesions in young adults. The average age of individuals was 24,59 years (SD 3,1). Nine hundred ninety-one (62%) lesions were found in females and 608 (38%) in males. More than half of pathologies were cystic lesions of odontogenic origin (822/51.4%), followed by periapical inflammation (282/17.6%). Regarding the site of lesions, more than half occurred in posterior mandible (877/54.8%), followed by posterior maxilla (339/21.2%). The most frequent entities were periapical cyst, chronic periapical granuloma, dental follicle and paradental cyst, corresponding to a total of 1,202 (75.2%) evaluated cases. In relation to the analysis of concordance between clinical and histological diagnosis the general Kappa index was 0.5, which is considered moderate. Finally, the findings confirm data from literature about the most frequent jaw pathologies in young adults and serve as aid for preventive measures of some entities. Additionally, they can improve the formulation of differential diagnosis and the patient management

  15. Modulation operated by the sympathetic nervous system on jaw reflexes and masticatory movement.

    Science.gov (United States)

    Passatore, Magda; Roatta, Silvestro

    2007-04-01

    The sympathetic nervous system (SNS), that is activated under condition of physical, psychological and psychosocial stress, affects force production and fatigability of muscles by controlling both muscle blood flow and the intracellular contractile mechanism. In addition SNS may affect motor function by modulating afferent activity from muscle spindles that are highly concentrated in jaw-closing muscles. Possible implications of these actions on masticatory function and myofascial pain are discussed.

  16. Pneumatic muscle actuated parallel asymmetrical gripper system with one mobile jaw

    Directory of Open Access Journals (Sweden)

    Deaconescu Tudor

    2017-01-01

    Full Text Available The paper pertains to the field of the current global endeavours in industrial robot construction, the presented research being oriented towards identifying innovative constructive solutions for gripper systems. The utilisation of the linear pneumatic muscle as actuator of the gripper system ensures a construction that is light, highly compliant, and that meets the safety requirements related to interaction with humans. The paper further presents and discusses such a system of asymmetrical construction with a single mobile jaw.

  17. [Analysis of variation of sagittal position of the jaw bones in skeletal Class III malocclusion].

    Science.gov (United States)

    Stojanović, Zdenka; Nikolić, Predrag; Nikodijević, Angelina; Milić, Jasmina; Duka, Milos

    2012-12-01

    Skeletal Class III malocclusion is a discrepancy in the sagittal jaw relationship, due to imbalances in their development and/or position, resulting in the dominant appearance of the lower jaw in facial profile. The aim of this study was to determine variations in the sagittal position of the jaw bones to the cranial base in subjects with skeletal Class III, for the earliest possible diagnosis of malocclusion. Fifty children and as many adults with skeletal Class III, both sexes, were examined and selected, based on the findings of sagittal interjaw relationship (ANB) children aged 6-12 years, and another group, of adults aged 18-26 years. We measured the angles of maxillary prognathism (SNA), mandibular prognathism (SNB) and ANB. Based on these results, within the respective groups subclassification into the subgroups was done, among which a significant difference measured values was evaluated. In both groups a significant correlation of the determined values was evaluated. An average SNA angle ranged 77.36 +/- 3.58 in children and 77.32 +/- 4.88 in adults, while an average SNB angle was 79.46 +/- 3.91 in the group of children and 81.12 +/- 3.76 in adults. An average ANB angle was -2.10 +/- 2.07 in children, and -4.00 +/- 2.34 in adults. In both groups, a significant correlation between the measured values and a significant difference in the values of all the measured parameters were found between patients from different subgroups (p children and adults. Sagittal position of the lower jaw in most of the adults was prognathic, while mandible prognathism in the children was less present.

  18. Brown tumor of the jaw after pregnancy and lactation in a MEN1 patient

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    Anna Casteràs

    2016-11-01

    Full Text Available Skeletal manifestations of primary hyperparathyroidism (pHPT include brown tumors (BT, which are osteoclastic focal lesions often localized in the jaws. Brown tumors are a rare manifestation of pHTP in Europe and USA; however, they are frequent in developing countries, probably related to vitamin D deficiency and longer duration and severity of disease. In the majority of cases, the removal of the parathyroid adenoma is enough for the bone to remineralize, but other cases require surgery. Hyperparathyroidism in MEN1 develops early, and is multiglandular and the timing of surgery remains questionable. To our knowledge, there are no reports of BT in MEN 1 patients. We present a 29-year-old woman with MEN 1 who developed a brown tumor of the jaw 24 months after getting pregnant, while breastfeeding. Serum corrected calcium remained under 2.7 during gestation, and at that point reached a maximum of 2.82 mmol/L. Concomitant PTH was 196 pg/mL, vitamin D 13.7 ng/mL and alkaline phosphatase 150 IU/L. Bone mineral density showed osteopenia on spine and femoral neck (both T-scores = −1.6. Total parathyroidectomy was performed within two weeks, with a failed glandular graft autotransplantation, leading to permanent hypoparathyroidism. Two months after removal of parathyroid glands, the jaw tumor did not shrink; thus, finally it was successfully excised. We hypothesize that higher vitamin D and mineral requirements during maternity may have triggered an accelerated bone resorption followed by appearance of the jaw BT. We suggest to treat pHPT before planning a pregnancy in MEN1 women or otherwise supplement with vitamin D, although this approach may precipitate severe hypercalcemia.

  19. Left Main Coronary Artery Aneurysm

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    Hossein Doustkami

    2016-07-01

    Full Text Available Aneurysms of the left main coronary artery are exceedingly rare clinical entities, encountered incidentally in approximately 0.1% of patients who undergo routine angiography. The most common cause of coronary artery aneurysms is atherosclerosis. Angiography is the gold standard for diagnosis and treatment. Depending on the severity of the coexisting coronary stenosis, patients with left main coronary artery aneurysms can be effectively managed either surgically or pharmacologically. We herein report a case of left main coronary artery aneurysm in a 72-year-old man with a prior history of hypertension presenting to our hospital because of unstable angina. The electrocardiogram showed ST-segment depression and T-wave inversion in the precordial leads. All the data of blood chemistry were normal. Echocardiography showed akinetic anterior wall, septum, and apex, mild mitral regurgitation and ejection fraction of 45%. Coronary angiography revealed a saccular aneurysm of the left main coronary artery with significant stenosis in the left anterior descending, left circumflex, and right coronary artery. The patient immediately underwent coronary artery bypass grafting and ligation of the aneurysm. At six months’ follow-up, he remained asymptomatic.

  20. Right colon cancer: Left behind.

    Science.gov (United States)

    Gervaz, P; Usel, M; Rapiti, E; Chappuis, P; Neyroud-Kaspar, I; Bouchardy, C

    2016-09-01

    Prognosis of colon cancer (CC) has steadily improved during the past three decades. This trend, however, may vary according to proximal (right) or distal (left) tumor location. We studied if improvement in survival was greater for left than for right CC. We included all CC recorded at the Geneva population-based registry between 1980 and 2006. We compared patients, tumor and treatment characteristics between left and right CC by logistic regression and compared CC specific survival by Cox models taking into account putative confounders. We also compared changes in survival between CC location in early and late years of observation. Among the 3396 CC patients, 1334 (39%) had right-sided and 2062 (61%) left-sided tumors. In the early 1980s, 5-year specific survival was identical for right and left CCs (49% vs. 48%). During the study period, a dramatic improvement in survival was observed for patients with left-sided cancers (Hazard ratio [HR]: 0.42, 95% confidence interval [CI]: 0.29-0.62, p colon cancer patients, those with right-sided lesions have by far the worse prognosis. Change of strategic management in this subgroup is warranted. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Experimental low-level jaw clenching inhibits temporal summation evoked by electrical stimulation in healthy human volunteers.

    Science.gov (United States)

    Tada, Hiroaki; Torisu, Tetsurou; Tanaka, Mihoko; Murata, Hiroshi; De Laat, Antoon; Svensson, Peter

    2015-05-01

    To examine the effect of low-level jaw clenching on temporal summation in healthy volunteers. In 18 healthy volunteers, the pain intensities evoked at the masseter muscle and the hand palm by the first and last stimuli in a train of repeated electrical stimuli (0.3 or 2.0 Hz) were rated using 0-100mm visual analogue scales (VAS), in order to evaluate temporal summation before and after three types of jaw-muscle tasks: low-level jaw clenching, repetitive gum chewing and mandibular rest position. A set of concentric surface electrodes with different diameters (small and large) was used for the electrical stimulation. The temporal summation evoked by the large diameter electrode with 2.0 Hz stimulation decreased significantly both on the masseter and the hand after low-level clenching (P ≤ 0.03), but did not show any significant change after the other tasks (P > 0.23). The VAS score of the first stimulation did not show any significant changes after low-level clenching (P > 0.57). Experimental low-level jaw clenching can inhibit pain sensitivity, especially temporal summation. Low-level jaw clenching can modify pain sensitivity, most likely through the central nervous system. The findings suggest that potential harmful low-level jaw clenching or tooth contacting could continue despite painful symptoms, e.g., temporomandibular disorders. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Stability of simultaneously placed dental implants with autologous bone grafts harvested from the iliac crest or intraoral jaw bone.

    Science.gov (United States)

    Kang, Young-Hoon; Kim, Hyun-Min; Byun, June-Ho; Kim, Uk-Kyu; Sung, Iel-Yong; Cho, Yeong-Cheol; Park, Bong-Wook

    2015-12-30

    Jaw bone and iliac bone are the most frequently used autologous bone sources for dental implant placement in patients with atrophic alveolar ridges. However, the comparative long-term stability of these two autologous bone grafts have not yet been investigated. The aim of this study was to compare the stability of simultaneously placed dental implants with autologous bone grafts harvested from either the iliac crest or the intraoral jaw bone for severely atrophic alveolar ridges. In total, 36 patients (21 men and 15 women) were selected and a retrospective medical record review was performed. We compared the residual increased bone height of the grafted bone, peri-implantitis incidence, radiological density in newly generated bones (HU values), and implant stability using resonance frequency analysis (ISQ values) between the two autologous bone graft groups. Both autologous bone graft groups (iliac bone and jaw bone) showed favorable clinical results, with similar long-term implant stability and overall implant survival rates. However, the grafted iliac bone exhibited more prompt vertical loss than the jaw bone, in particular, the largest vertical bone reduction was observed within 6 months after the bone graft. In contrast, the jaw bone graft group exhibited a slower vertical bone resorption rate and a lower incidence of peri-implantitis during long-term follow-up than the iliac bone graft group. These findings demonstrate that simultaneous dental implantation with the autologous intraoral jaw bone graft method may be reliable for the reconstruction of edentulous atrophic alveolar ridges.

  3. Jaw Dysfunction Is Associated with Neck Disability and Muscle Tenderness in Subjects with and without Chronic Temporomandibular Disorders

    Directory of Open Access Journals (Sweden)

    A. Silveira

    2015-01-01

    Full Text Available Purpose. Tender points in the neck are common in patients with temporomandibular disorders (TMD. However, the correlation among neck disability, jaw dysfunction, and muscle tenderness in subjects with TMD still needs further investigation. This study investigated the correlation among neck disability, jaw dysfunction, and muscle tenderness in subjects with and without chronic TMD. Participants. Forty females between 19 and 49 years old were included in this study. There were 20 healthy controls and 20 subjects who had chronic TMD and neck disability. Methods. Subjects completed the neck disability index and the limitations of daily functions in TMD questionnaires. Tenderness of the masticatory and cervical muscles was measured using an algometer. Results. The correlation between jaw disability and neck disability was significantly high (r=0.915, P<0.05. The correlation between level of muscle tenderness in the masticatory and cervical muscles with jaw dysfunction and neck disability showed fair to moderate correlations (r=0.32–0.65. Conclusion. High levels of muscle tenderness in upper trapezius and temporalis muscles correlated with high levels of jaw and neck dysfunction. Moreover, high levels of neck disability correlated with high levels of jaw disability. These findings emphasize the importance of considering the neck and its structures when evaluating and treating patients with TMD.

  4. Molecular phylogenetics and diversification of trap-jaw ants in the genera Anochetus and Odontomachus (Hymenoptera: Formicidae).

    Science.gov (United States)

    Larabee, Fredrick J; Fisher, Brian L; Schmidt, Chris A; Matos-Maraví, Pável; Janda, Milan; Suarez, Andrew V

    2016-10-01

    Ants in the genera Anochetus and Odontomachus belong to one of the largest clades in the subfamily Ponerinae, and are one of four lineages of ants possessing spring-loaded "trap-jaws." Here we present results from the first global species-level molecular phylogenetic analysis of these trap-jaw ants, reconstructed from one mitochondrial, one ribosomal RNA, and three nuclear protein-coding genes. Bayesian and likelihood analyses strongly support reciprocal monophyly for the genera Anochetus and Odontomachus. Additionally, we found strong support for seven trap-jaw ant clades (four in Anochetus and three in Odontomachus) mostly concordant with geographic distribution. Ambiguity remains concerning the closest living non-trap-jaw ant relative of the Anochetus+Odontomachus clade, but Bayes factor hypothesis testing strongly suggests that trap-jaw ants evolved from a short mandible ancestor. Ponerine trap-jaw ants originated in the early Eocene (52.5Mya) in either South America or Southeast Asia, where they have radiated rapidly in the last 30million years, and subsequently dispersed multiple times to Africa and Australia. These results will guide future taxonomic work on the group and act as a phylogenetic framework to study the macroevolution of extreme ant mouthpart specialization. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Central giant cell granuloma of the jaws: clinical and radiological evaluation of 22 cases

    International Nuclear Information System (INIS)

    Sun, Zhi-Jun; Cai, Yu; Zhao, Yi-Fang; Zwahlen, Roger A.; Zheng, Yun-Fei; Wang, Shi-Ping

    2009-01-01

    The objective was to investigate the clinical and radiological characteristics of central giant cell granulomas (CGCGs) of the jaws. A retrospective analysis of a 20-year database was performed regarding both clinical and radiological features of 22 patients affected with CGCGs of the jaws. Fourteen women and 8 men were included with the age range of 7-81 years (mean 31.7 years). Among the 22 lesions, 16 were located in the mandible and 6 in the maxilla. Painless swelling was the most common clinical feature in 18 of all cases. Limited mouth opening was noted in 2 patients where the lesions involved the condyle. Radiographically, 13 lesions were homogeneously osteolytic and 9 lesions were trabeculated. Fifteen lesions were unilocular and 14 lesions presented with well-defined but not sclerotic margins. CT images in 5 patients clearly showed the trabeculation within the lesions. The follow-up ranged from 1.5 to 11 years with a mean period of 5 years. Three out of 9 aggressive and 1 out of 13 nonaggressive lesions developed recurrence. Diagnosis of CGCGs of the jaws depends on both correct interpretation of clinical, radiographic and pathological data. Differentiation between aggressive and nonaggressive CGCGs should be considered to improve individual treatment planning. (orig.)

  6. Severe osteonecrosis of the jaws in a compromised patient subjected to bisphosphonate therapy

    Directory of Open Access Journals (Sweden)

    Juliana Dreyer de Menezes

    Full Text Available Bisphosphonate-related osteonecrosis of the jaws is characterized by alveolar bone exposure, especially after mucosal trauma or after surgical procedures, in patients who have previously received or who are currently receiving bisphosphonates without a history of radiation therapy in the maxillofacial region. The condition is refractory to treatment, and attempts at debridement are not completely effective in eradicating the necrotic bone. We report here a case of a severe osteonecrosis of the jaws in a 77-year-old male patient, who had been subjected to chemotherapy and treatment with zoledronic acid and corticosteroid. The patient also had comorbidities such as diabetes and periodontal disease, which might have contributed to the lesion development. Bisphosphonate-related osteonecrosis of the jaws has become a reality in dental clinical practice. Although palliative treatment aiming at controlling pain, infection and injury progression is indicated, the therapeutic strategy is still challenging. So far, the best approach available is prevention, based on oral care before, during, and after bisphosphonate therapy.

  7. Bisphosphonate-related osteonecrosis of the jaw: data from the French national pharmacovigilance database.

    Science.gov (United States)

    de Boissieu, Paul; Gaboriau, Louise; Morel, Aurore; Trenque, Thierry

    2016-10-01

    The aim of this study was to describe bisphosphonate-related osteonecrosis of the jaw (BRONJ) in the French national pharmacovigilance database. BRONJ was identified with the standardized MedDRA query (SMQ) 'osteonecrosis' among all data from 1985 to 31 December 2014. Because this SMQ was not specific to the jaw localization, selection of cases based on anatomy was performed after data extraction. For each case, demographic and medical information was analysed, as well as data about notification (year of notification, year of occurrence, outcome, seriousness). Known associated factors for BRONJ were also documented: dentoalveolar surgery, glucocorticoids, chemotherapy, anti-angiogenics, denosumab. Among 1404 SMQ notifications, 663 were located in the jaws and 629 were associated with bisphosphonate use. BRONJ reported in the database mainly affected women (n = 443, 71%) with an oncological indication (n = 440, 70%). BRONJ was considered as serious in 91%. Outcome was unfavourable for 92% of cases. Associated factors were identified for 70% of the patients. A peak of notification was noted in 2014 (13% of all cases), but on analysis by year of occurrence instead of by year of notification, this peak disappeared. SMQ 'osteonecrosis' appears to be an adequate tool to analyse BRONJ in a pharmacovigilance database. © 2016 Société Française de Pharmacologie et de Thérapeutique.

  8. Contrast-enhanced dental MRI for visualization of the teeth and jaw.

    Science.gov (United States)

    Olt, Silvia; Jakob, Peter M

    2004-07-01

    A technique for contrast-enhanced dental MRI is described that enables 3D visualization of the oral cavity, including the jaw and teeth. Since teeth are MR-invisible, the basic principle of this technique is that the teeth and jaw can be observed indirectly through contrast with a surrounding MR-visible medium. For this purpose, the oral cavity is filled with a nontoxic substance, such as water or MR contrast media, that gives a high MR signal. A 3D data set covering the entire buccal space is acquired, and the image intensities are inverted. Since isosurface reconstructions of the teeth and jaw, as well as panoramic views analogous to orthopantomography, can be extracted from these data, contrast-enhanced dental MRI may be useful as a flexible tool for dentistry and orthodontics. Moreover, contrast-enhanced dental MRI works without radiation exposure, and therefore it is an interesting alternative to X-ray-based imaging modalities such as conventional radiography and dental CT. In this article, some preliminary results obtained with contrast-enhanced dental MRI are shown in order to demonstrate the feasibility and performance of this new approach. Copyright 2004 Wiley-Liss, Inc.

  9. Intraosseous myofibroma of mandible: A rarity of jaws: With clinical, radiological, histopathological and immunohistochemical features.

    Science.gov (United States)

    Sundaravel, Subbaraj; Anuthama, Krishnamurthy; Prasad, Harikrishnan; Sherlin, Herald J; Ilayaraja, Vadivel

    2013-01-01

    Myofibroma is an uncommon benign mesenchymal neoplasm composed of myofibroblasts, but it can be confused with more aggressive spindle cell tumors. Solitary myofibroma is common in soft tissues of head and neck, but rare in the jaw bones with only 38 cases of central myofibroma of mandible reported in English medical literature. When encountered in the jaws, lesions exhibit clinical and radiographic features suggestive of odontogenic cysts/tumors or other neoplastic conditions. We hereby present the 39(th) case of intraosseous myofibroma of the mandible which had been reported to our institution. A 16-year-old male reported with a chief complaint of swelling in the right side of face. Intraorally there was a firm, nontender swelling in the right buccal aspect of the mandible. Radiologically the lesion was osteolytic, destroying the buccal cortical plate. Histologically, characteristic biphasic pattern of myofibroma was noticed. Immunoreactivity was positive for vimentin and αSMA but negative for desmin, thus confirming our diagnosis. The patient was treated by local-wide surgical excision of the lesion. A 3-year follow-up revealed no signs of recurrence. Occurrence of myofibroma involving the jaw bones is common in the younger age groups and represents a unique diagnostic and therapeutic challenge. Differentiating this lesion from other benign and malignant neoplasms is crucial in deciding between a radical and a conservative treatment approach.

  10. Radiolucent rim as a possible diagnostic aid for differentiating jaw lesions

    Energy Technology Data Exchange (ETDEWEB)

    Mortazavi, Hamed; Baharvand, Maryam; Rarahmani, Somayeh; Jafati, Soudeh; Parvaei, Parvin [Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran (Iran, Islamic Republic of)

    2015-12-15

    In this study, we formulate a new proposal that complements previous classifications in order to assist dental practitioners in performing a differential diagnosis based on patients' radiographs. We used general search engines and specialized databases such as Google Scholar, PubMed, PubMed Central, MedLine Plus, Science Direct, Scopus, and well-recognized textbooks to find relevant studies by using keywords such as 'jaw disease,' 'jaw lesions,' 'radiolucent rim,' 'radiolucent border,' and 'radiolucent halo.' More than 200 articles were found, of which 70 were broadly relevant to the topic. We ultimately included 50 articles that were closely related to the topic of interest. When the relevant data were compiled, the following eight lesions were identified as having a radiolucent rim: periapical cemento-osseous dysplasia, focal cemento-osseous dysplasia, florid cemento-osseous dysplasia, cemento-ossifying fibroma, osteoid osteoma, osteoblastoma, odontoma, and cementoblastoma. We propose a novel subcategory, jaw lesions with a radiolucent rim, which includes eight entities. The implementation of this new category can help improve the diagnoses that dental practitioners make based on patients' radiographs.

  11. Variation in the shape and mechanical performance of the lower jaws in ceratopsid dinosaurs (Ornithischia, Ceratopsia).

    Science.gov (United States)

    Maiorino, Leonardo; Farke, Andrew A; Kotsakis, Tassos; Teresi, Luciano; Piras, Paolo

    2015-11-01

    Ceratopsidae represents a group of quadrupedal herbivorous dinosaurs that inhabited western North America and eastern Asia during the Late Cretaceous. Although horns and frills of the cranium are highly variable across species, the lower jaw historically has been considered to be relatively conservative in morphology. Here, the lower jaws from 58 specimens representing 21 ceratopsoid taxa were sampled, using geometric morphometrics and 2D finite element analysis (FEA) to explore differences in morphology and mechanical performance across Ceratopsoidea (the clade including Ceratopsidae, Turanoceratops and Zuniceratops). Principal component analyses and non-parametric permuted manovas highlight Triceratopsini as a morphologically distinct clade within the sample. A relatively robust and elongate dentary, a larger and more elongated coronoid process, and a small and dorso-ventrally compressed angular characterize this clade, as well as the absolutely larger size. By contrast, non-triceratopsin chasmosaurines, Centrosaurini and Pachyrhinosaurini have similar morphologies to each other. Zuniceratops and Avaceratops are distinct from other taxa. No differences in size between Pachyrhinosaurini and Centrosaurini are recovered using non-parametric permuted anovas. Structural performance, as evaluated using a 2D FEA, is similar across all groups as measured by overall stress, with the exception of Triceratopsini. Shape, size and stress are phylogenetically constrained. A longer dentary as well as a long coronoid process result in a lower jaw that is reconstructed as relatively much more stressed in triceratopsins. © 2015 Anatomical Society.

  12. Convergent evolution of jaws between spinosaurid dinosaurs and pike conger eels

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    Romain Vullo

    2016-12-01

    Full Text Available Spinosaurs represent a group of peculiar theropod dinosaurs that have often been described as “crocodile-mimic”, predominantly fish-eating predators, and recently claimed to have been semi-aquatic animals. Here we report a suite of craniodental characters unexpectedly shared by spinosaurs and pike conger eels. Pike conger eels are predatory, mainly piscivorous bottom-dwelling anguilliform fishes that inhabit marine and brackish environments. These two groups of dinosaurs and fishes show a mediolaterally compressed, elongated rostrum, a terminal “rosette” bearing enlarged teeth in both upper and lower jaws, and a notch posterior to the premaxillary “rosette” characterized by the presence of reduced teeth. The morphological convergence observed in the jaws of these two distantly related groups of vertebrates may result from similar feeding behaviours. This typical jaw morphology likely represents an effective biomechanical adaptation for biting and grabbing elusive prey items in low-light aquatic environments. Associated with this specialized snout morphology, numerous integumentary mechanoreceptors involved in prey detection are present in both spinosaurs and pike congers. Our new observations provide an additional convincing argument regarding the decades-long and widely debated lifestyle of spinosaurs.

  13. Jaw osteonecrosis management around a dental implant inserted 2 years before starting treatment with zoledronic acid.

    Science.gov (United States)

    Marín-Fernández, Ana-Belén; García Medina, Blas; Aguilar-Salvatierra, Antonio; Jiménez-Burkhardt, Alberto; Gómez-Moreno, Gerardo

    2015-07-01

    Bisphosphonates (BP) are a type of drug known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and so bone resorption. BPs are widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw (ONJ). Zoledronic acid (ZA) is an intravenous BP used in the treatment and prophylaxis of bone disease in patients with malignant tumors with bone implication. ZA is the most potent BP in clinical development. This report describes the case of a 62-year-old woman with breast cancer antecedents which relapsed, who had received a maxillary dental implant two years before the start of therapy with zoledronic acid. She later developed osteonecrosis of the jaw (ONJ), which began in the peri-implant area, and was treated for stage 3 ONJ by sub-total maxillectomy. Key words:Bisphosphonates, zoledronic acid, osteonecrosis of the jaw, peri-implantitis, maxillectomy.

  14. Bisphosphonate-related osteonecrosis of the jaw in cancer patients: Implications for nurses.

    Science.gov (United States)

    Morris, Monica; Cruickshank, Susanne

    2010-07-01

    This paper reports a review of the literature with a specific focus on osteonecrosis of the jaw. Bisphosphonate drugs are commonly used in the treatment of bone disease secondary to myeloma and solid tumours, such as breast and prostate cancer. In the past few years, an uncommon but distressing condition known as osteonecrosis of the jaw (ONJ) has been detected in patients who are having bisphosphonate treatment, particularly the intravenous (IV) preparations. Osteonecrosis of the jaw results from bone exposure in the oral cavity with subsequent death of bone tissue (necrosis). The review searched key databases including Medline, British Nursing Index, Cochrane, and meeting abstracts to ascertain the extent of literature in this field. Fourty-two articles were reviewed which described the clinical manifestations of ONJ, the reported incidence and clinical cases. The results indicate there is an emerging body of evidence in this field and nurses delivering bisphosphonates need to familiarise themselves with the current guidance to ensure risks are minimised for patients.

  15. Use of Vancomycin-Impregnated Calcium Sulfate in the Treatment of Osteomyelitis of the Jaw.

    Science.gov (United States)

    Sun, Hai-Jiang; Xue, Lei; Wu, Chuan-Bin; Zhou, Qing

    2017-01-01

    The aim of this study was to describe the effect of vancomycin-impregnated calcium sulfate in the treatment of osteomyelitis of the jaw. Twelve patients who were diagnosed with osteomyelitis of the jaw underwent treatment with vancomycin-impregnated calcium sulfate since July 2014 at the Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University (Shenyang, China). All patients underwent debridement of nonviable bone and implantation of vancomycin-impregnated calcium sulfate. The wounds were covered with an acellular dermal matrix and sutured. Ten patients had satisfactory wound healing. However, 2 cases of maxillary central osteomyelitis had delayed wound healing. The wounds healed after the surgical site was resutured under local anesthesia. At 3 months, the panoramic radiograph showed that most implants had been reabsorbed and replaced by new bone formation. All patients in this study had no recurrence of infection at 6 to 18 months (mean, 10.8 months) of follow-up. The use of vancomycin-impregnated calcium sulfate in the surgical debridement site for chronic osteomyelitis of the jaw has shown encouraging results. In addition, calcium sulfate can promote the formation of new bone to a certain extent. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  16. Processing system of jaws tomograms for pathology identification and surgical guide modeling

    International Nuclear Information System (INIS)

    Putrik, M. B.; Ivanov, V. Yu.; Lavrentyeva, Yu. E.

    2015-01-01

    The aim of the study is to create an image processing system, which allows dentists to find pathological resorption and to build surgical guide surface automatically. X-rays images of jaws from cone beam tomography or spiral computed tomography are the initial data for processing. One patient’s examination always includes up to 600 images (or tomograms), that’s why the development of processing system for fast automation search of pathologies is necessary. X-rays images can be useful not for only illness diagnostic but for treatment planning too. We have studied the case of dental implantation – for successful surgical manipulations surgical guides are used. We have created a processing system that automatically builds jaw and teeth boundaries on the x-ray image. After this step, obtained teeth boundaries used for surgical guide surface modeling and jaw boundaries limit the area for further pathologies search. Criterion for the presence of pathological resorption zones inside the limited area is based on statistical investigation. After described actions, it is possible to manufacture surgical guide using 3D printer and apply it in surgical operation

  17. Radiolucent rim as a possible diagnostic aid for differentiating jaw lesions

    International Nuclear Information System (INIS)

    Mortazavi, Hamed; Baharvand, Maryam; Rarahmani, Somayeh; Jafati, Soudeh; Parvaei, Parvin

    2015-01-01

    In this study, we formulate a new proposal that complements previous classifications in order to assist dental practitioners in performing a differential diagnosis based on patients' radiographs. We used general search engines and specialized databases such as Google Scholar, PubMed, PubMed Central, MedLine Plus, Science Direct, Scopus, and well-recognized textbooks to find relevant studies by using keywords such as 'jaw disease,' 'jaw lesions,' 'radiolucent rim,' 'radiolucent border,' and 'radiolucent halo.' More than 200 articles were found, of which 70 were broadly relevant to the topic. We ultimately included 50 articles that were closely related to the topic of interest. When the relevant data were compiled, the following eight lesions were identified as having a radiolucent rim: periapical cemento-osseous dysplasia, focal cemento-osseous dysplasia, florid cemento-osseous dysplasia, cemento-ossifying fibroma, osteoid osteoma, osteoblastoma, odontoma, and cementoblastoma. We propose a novel subcategory, jaw lesions with a radiolucent rim, which includes eight entities. The implementation of this new category can help improve the diagnoses that dental practitioners make based on patients' radiographs

  18. Small vertical changes in jaw relation affect motor unit recruitment in the masseter.

    Science.gov (United States)

    Terebesi, S; Giannakopoulos, N N; Brüstle, F; Hellmann, D; Türp, J C; Schindler, H J

    2016-04-01

    Strategies for recruitment of masseter muscle motor units (MUs), provoked by constant bite force, for different vertical jaw relations have not previously been investigated. The objective of this study was to analyse the effect of small changes in vertical jaw relation on MU recruitment behaviour in different regions of the masseter during feedback-controlled submaximum biting tasks. Twenty healthy subjects (mean age: 24·6 ± 2·4 years) were involved in the investigation. Intra-muscular electromyographic (EMG) activity of the right masseter was recorded in different regions of the muscle. MUs were identified by the use of decomposition software, and root-mean-square (RMS) values were calculated for each experimental condition. Six hundred and eleven decomposed MUs with significantly (P vertical jaw relations. These fine-motor skills might be responsible for its excellent functional adaptability and might also explain the successful management of temporomandibular disorder patients by somatic intervention, in particular by the use of oral splints. © 2015 John Wiley & Sons Ltd.

  19. Aphasia following left thalamic hemorrhage

    International Nuclear Information System (INIS)

    Makishita, Hideo; Miyasaka, Motomaro; Tanizaki, Yoshio; Yanagisawa, Nobuo; Sugishita, Morihiro.

    1984-01-01

    We reported 7 patients with left thalamic hemorrhage in the chronic stage (from 1.5 months to 4.5 months), and described language disorders examined by Western Aphasia Battery (WAB) and measured cerebral blood flow by single photon emission CT. Examination of language by WAB revealed 4 aphasics out of 7 cases, and 3 patients had no language deficit. The patient with Wernicke's aphasia showed low density area only in the left posterior thalamus in X-ray CT, and revealed severe low blood flow area extending to left temporal lobe in emission CT. In the case with transcortical sensory aphasia, although X-ray CT showed no obvious low density area, emission CT revealed moderate low flow area in watershed area that involved the territory between posterior cerebral and middle cerebral arteries in the left temporooccipital region in addition to low blood flow at the left thalamus. In one of the two patients classified as anomic aphasia, whose score of repetition (8.4) was higher than that of comprehension (7.4), emission CT showed slight low flow area at the temporo-occipital region similarly as the case with transcortical sensory aphasia. In another case with anomic aphasia, scored 9 on both fluensy and comprehension subtests and 10 on repetition, there was wide low density area all over the left thalamus and midline shift to the right in X-ray CT, and emission CT showed severe low blood flow in the same region spreading widely toward the cerebral surface. On the other hand, in all of the 3 patients without aphasia, emission CT showed low flow region restricted to the left thalamus. (J.P.N.)

  20. Accuracy of Intraoral Digital Impressions for Whole Upper Jaws, Including Full Dentitions and Palatal Soft Tissues.

    Science.gov (United States)

    Gan, Ning; Xiong, Yaoyang; Jiao, Ting

    2016-01-01

    Intraoral digital impressions have been stated to meet the clinical requirements for some teeth-supported restorations, though fewer evidences were proposed for larger scanning range. The aim of this study was to compare the accuracy (trueness and precision) of intraoral digital impressions for whole upper jaws, including the full dentitions and palatal soft tissues, as well as to determine the effect of different palatal vault height or arch width on accuracy of intraoral digital impressions. Thirty-two volunteers were divided into three groups according to the palatal vault height or arch width. Each volunteer received three scans with TRIOS intraoral scanner and one conventional impression of whole upper jaw. Three-dimensional (3D) images digitized from conventional gypsum casts by a laboratory scanner were chose as the reference models. All datasets were imported to a specific software program for 3D analysis by "best fit alignment" and "3D compare" process. Color-coded deviation maps showed qualitative visualization of the deviations. For the digital impressions for palatal soft tissues, trueness was (130.54±33.95)μm and precision was (55.26±11.21)μm. For the digital impressions for upper full dentitions, trueness was (80.01±17.78)μm and precision was (59.52±11.29)μm. Larger deviations were found between intraoral digital impressions and conventional impressions in the areas of palatal soft tissues than that in the areas of full dentitions (pimpressions for palatal soft tissues was slightly better than that for full dentitions (p = 0.049). There was no significant effect of palatal vault height on accuracy of digital impressions for palatal soft tissues (p>0.05), but arch width was found to have a significant effect on precision of intraoral digital impressions for full dentitions (p = 0.016). A linear correlation was found between arch width and precision of digital impressions for whole upper jaws (r = 0.326, p = 0.034 for palatal soft tissues and r