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Sample records for lee sang soo

  1. Lee Sang Gak Telescope (LSGT): A Remotely Operated Robotic Telescope for Education and Research at Seoul National University

    Science.gov (United States)

    Im, Myungshin; Choi, Changsu; Kim, Kihyun

    2015-08-01

    We introduce the Lee Sang Gak Telescope (LSGT), a remotely operated, robotic 0.43-meter telescope. The telescope was installed at the Siding Spring Observatory, Australia, in 2014 October, to secure regular and exclusive access to the dark sky and excellent atmospheric conditions in the southern hemisphere from the Seoul National University (SNU) campus. Here, we describe the LSGT system and its performance, present example images from early observations, and discuss a future plan to upgrade the system. The use of the telescope includes (i) long-term monitoring observations of nearby galaxies, active galactic nuclei, and supernovae; (ii) rapid follow-up observations of transients such as gamma-ray bursts and gravitational wave sources; and (iii) observations for educational activities at SNU. Based on observations performed so far, we find that the telescope is capable of providing images to a depth of R=21.5 mag (point source detection) at 5-σ with 15 min total integration time under good obs-erving conditions.

  2. Alessandra Angelini SooSoos

    Index Scriptorium Estoniae

    2008-01-01

    Itaalia kunstniku Alessandra Angelini ja Eesti Kunstiakadeemia koostöös sündinud näitus "The Tree of Wonders from Italy" galeriis SooSoo 5.-18. III. A. Angelini esitleb innovatiivseid interpretatsioone tööstusliku puitmaterjali kasutusest

  3. Effects of calcium impurity on phase relationship, ionic conductivity ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 3. Effects of calcium impurity on phase relationship, ionic conductivity and microstructure of Na + - β / b e t a " -alumina solid electrolyte. SUNG-TAE LEE DAE-HAN LEE SANG-MIN LEE SANG-SOO HAN SANG-HYUNG LEE SUNG-KI LIM. Volume 39 Issue 3 ...

  4. die bome reusagtig soos ons was. Hilda Smits. Pretoria: Protea ...

    African Journals Online (AJOL)

    om te dink later het die park 'n geheime taal begin praat die lig geluidloos soos deur Ma se sif geval die gras stil geword. In hierdie vers maak Smits gebruik van antropomorfisme waarin menslike eienskappe toegeskryf word aan nie- menslike wesens soos diere, plante en dinge, soos byvoorbeeld in reël 5 en reël 7 hierbo.

  5. En sang der er et overlevelsesudstyr

    DEFF Research Database (Denmark)

    Kock, Christian Erik J

    2015-01-01

    Fredmans Epistel N:o 81 er en af de Bellman-sange der oftest er blevet fortolket af sangere og grupper, og som synes at være blandt hans mest virkningsfulde. Hvad er dens virkning, og hvad beror den på? Læsningen her inddrager både ord og musik, lyd og tanke....

  6. 77 FR 67442 - Soo Line Railroad Company-Temporary Trackage Rights Exemption-BNSF Railway Company

    Science.gov (United States)

    2012-11-09

    ... Surface Transportation Board Soo Line Railroad Company--Temporary Trackage Rights Exemption-- BNSF Railway Company BNSF Railway Company (BNSF), pursuant to a written trackage rights agreement (Agreement), has agreed to grant temporary overhead trackage rights to Soo Line Railroad Company d/b/a Canadian Pacific...

  7. Genome-based exome sequencing analysis identifies GYG1, DIS3L ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 96; Issue 6. Genome-based exome sequencing analysis identifies GYG1, DIS3L and DDRGK1 are associated with myocardial infarction in Koreans. JI-YOUNG LEE SANGHOON MOON YUN KYOUNG KIM SANG-HAK LEE BOK-SOO LEE MIN-YOUNG PARK JEONG EUY PARK ...

  8. Die brein soos beskou deur die Grieke en Romeine

    Directory of Open Access Journals (Sweden)

    Francois P. Retief

    2015-02-01

    Full Text Available In Ou Egipte is mummifikasie met uitgebreide reseksie of uitsnyding van organe geassosieer, maar geen kennis is geneem van die morfologie van die brein nie. Griekse skrywers van die sesde en vyfde eeue v.C. het die brein aanvanklik gesien as die setel van intelligensie, die orgaan van sensoriese waarneming en gedeeltelik die oorsprong van sperma. Pneuma het ’n belangrike rol in breinfunksie gespeel. Hippokrates was die eerste om die brein te beskryf as ’n dubbele orgaan, wat met harsingvlies (meninges bedek, funksioneel van pneuma afhanklik en vertolker van begrip is. Tydgenote soos Plato, Aristoteles en Diokles het tot die beskrywing bygedra, maar laasgenoemde twee het beweer dat die hart die middelpunt van intelligensie is en nie die brein nie. Gedurende die laaste helfte van die vierde eeu v.C. is disseksie van die menslike liggaam tydelik aan die mediese skool van Alexandrië toegelaat en het dit tot merkwaardige vooruitgang in die begrip van die menslike anatomie en fisiologie gelei. Herofilus en Erasistratus het uitstekende beskrywings van die struktuur en funksie van die brein gegee wat eers in die tweede eeu n.C. deur Galenus geëwenaar is.

  9. Ta-Tsing-Leu-Lee

    OpenAIRE

    Staunton, George Thomas

    2017-01-01

    Anastatic reprint of Ta-Tsing-Leu-Lee o Sia Leggi Fondamentali del Codice Penale della China, stampato e promulgato a Pekin coll’autorità di tutti gl’Imperatori Ta-Tsing, della presente dinastìa. Tradotto dal chinese da Giorgio Tommaso Staunton, membro della Società reale di Londra […] Versione italiana […] 3 vols. (Milano: dalla Stamperia di Giovanni Silvestri agli Scalini del Duomo n° 994, 1812), Italian translation of George Thomas Staunton, Ta Tsing Leu Lee; Being the Funda...

  10. Growth characteristics and productivity of cold-tolerant “Kowinearly ...

    African Journals Online (AJOL)

    Growth characteristics and productivity of cold-tolerant “Kowinearly” Italian ryegrass in the northern part of South Korea. Gi Jun Choi, Hee Chung Ji, Ki-Yong Kim, Hyung Soo Park, Sung Seo, Ki-Won Lee, Sang-Hoon Lee ...

  11. 75 FR 47678 - Northern Plains Railroad, Inc.-Lease Exemption-Soo Line Railroad Company

    Science.gov (United States)

    2010-08-06

    ... Wheat Lines on June 17, 2010, and that it had served the notice on the national offices of the labor unions for such Soo employees on June 17, 2010. NPR stated that there are no labor unions that represent... general transportation importance. 49 CFR 1011.2(a)(6). Accordingly, the Board revokes the delegation to...

  12. Yang-Lee zeros of the Yang-Lee model

    Science.gov (United States)

    Mussardo, G.; Bonsignori, R.; Trombettoni, A.

    2017-12-01

    To understand the distribution of the Yang-Lee zeros in quantum integrable field theories we analyse the simplest of these systems given by the 2D Yang-Lee model. The grand-canonical partition function of this quantum field theory, as a function of the fugacity z and the inverse temperature β, can be computed in terms of the thermodynamics Bethe Ansatz based on its exact S-matrix. We extract the Yang-Lee zeros in the complex plane by using a sequence of polynomials of increasing order N in z which converges to the grand-canonical partition function. We show that these zeros are distributed along curves which are approximate circles as it is also the case of the zeros for purely free theories. There is though an important difference between the interactive theory and the free theories, for the radius of the zeros in the interactive theory goes continuously to zero in the high-temperature limit β → 0 while in the free theories it remains close to 1 even for small values of β, jumping to 0 only at β = 0 .

  13. The Earl Lee Street Art Campaign

    Science.gov (United States)

    Bubba

    2013-01-01

    This article describes a catchy phrase with more to its meaning than first view. A slogan "All the girls love Earl Lee," appears in street art around the world. Earl Lee is a lovable, handsome man who owns the fictitious Earl Lube industries. Originally intended to bring a smile to people's faces at a time when there wasn't much to smile…

  14. Characterization of Phenolic Compounds in Wine Lees

    Directory of Open Access Journals (Sweden)

    Ye Zhijing

    2018-03-01

    Full Text Available The effect of vinification techniques on phenolic compounds and antioxidant activity of wine lees are poorly understood. The present study investigated the antioxidant activity of white and red wine lees generated at early fermentation and during aging. In this study, the total phenol content (TPC, total tannin content (TTC, mean degree of polymerization (mDP, and antioxidant activities of five white and eight red wine lees samples from different vinification backgrounds were determined. The results showed that vinification techniques had a significant (p < 0.05 impact on total phenol and tannin content of the samples. White wine lees had high mDP content compared with red ones. Catechin (50–62% and epicatechin contents were the predominant terminal units of polymeric proanthocyanidin extracted from examined samples. Epigallocatechin was the predominant extension unit of white wine lees, whereas epicatechin was the predominant compound in red wine marc. The ORAC (oxygen radical absorbance capacity assay was strongly correlated with the DPPH (α, α-diphenyl-β-picrylhydrazyl assay, and the results showed the strong antioxidant activities associated with red wine lees (PN > 35 mg Trolox/g FDM (PN: Pinot noir lees; FDM: Freeze-dried Material. This study indicates that tannin is one of the major phenolic compounds available in wine lees that can be useful in human and animal health applications.

  15. Tim Berners-Lee during the WSIS

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Tim Berners-Lee stands in front of the first web server at the Geneva Palexpo during the World Summit on the Information Society (WSIS) in 2003. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  16. Characterization of Phenolic Compounds in Wine Lees.

    Science.gov (United States)

    Zhijing, Ye; Shavandi, Amin; Harrison, Roland; Bekhit, Alaa El-Din A

    2018-03-25

    The effect of vinification techniques on phenolic compounds and antioxidant activity of wine lees are poorly understood. The present study investigated the antioxidant activity of white and red wine lees generated at early fermentation and during aging. In this study, the total phenol content (TPC), total tannin content (TTC), mean degree of polymerization (mDP), and antioxidant activities of five white and eight red wine lees samples from different vinification backgrounds were determined. The results showed that vinification techniques had a significant ( p 35 mg Trolox/g FDM) (PN: Pinot noir lees; FDM: Freeze-dried Material). This study indicates that tannin is one of the major phenolic compounds available in wine lees that can be useful in human and animal health applications.

  17. "Tallinn Jazz Weekend" tõi kultuuripealinna Euroopa jazzielu korraldajad / Marje Ingel, Joosep Sang

    Index Scriptorium Estoniae

    Ingel, Marje

    2011-01-01

    Jazziorganisatsioonist Europe Jazz Network ja selle aastakonverentsist Tallinnas ning J. Sang selle raames Von Krahli teatris toimunud Tallinn Jazz Weekendi eesti jazzmuusika showcase-festivalist lühidalt

  18. The Statecraft of Singapore's Lee Kuan Yew

    National Research Council Canada - National Science Library

    Toh, K

    1996-01-01

    .... The ejection of Singapore from the Federation led Lee to focus on two strategic goals: the survival of Singapore as an independent state while simultaneously pursuing nation-building under the threats of communism and internal ethnic conflicts...

  19. Higher-derivative Lee-Wick unification

    International Nuclear Information System (INIS)

    Carone, Christopher D.

    2009-01-01

    We consider gauge coupling unification in Lee-Wick extensions of the Standard Model that include higher-derivative quadratic terms beyond the minimally required set. We determine how the beta functions are modified when some Standard Model particles have two Lee-Wick partners. We show that gauge coupling unification can be achieved in such models without requiring the introduction of additional fields in the higher-derivative theory and we comment on possible ultraviolet completions.

  20. Use of Awamori-pressed Lees and Tofu Lees as Feed Ingredients for Growing Female Goats

    Directory of Open Access Journals (Sweden)

    Itsuki Nagamine

    2012-12-01

    Full Text Available Okinawan Awamori is produced by fermenting steamed indica rice with black mold, yeast, and water. Awamori-pressed lees is a by-product of the Awamori production process. Tofu lees is a by-product of the Tofu production process. This research consisted of two experiments conducted to elucidate whether or not dried Awamori-pressed lees and Tofu lees can be used as a mixed feed ingredient for raising female goats. In experiment 1, digestion trials were conducted to ascertain the nutritive values of dried Awamori-pressed lees and dried Tofu lees for goats. The digestible crude protein (DCP and total digestible nutrients (TDN contents of dried Awamori-pressed lees and Tofu lees were 22.5%, 22.5% (DCP, and 87.2%, 94.4% (TDN respectively. In experiment 2, 18 female goats (Japanese Saanen×Nubian, three months old, body weight 15.4±0.53 kg were divided into three groups of six animals (control feed group (CFG, Awamori-pressed lees mixed feed group (AMFG, Tofu lees mixed feed group (TMFG. The CFG control used feed containing 20% soybean meal as the main protein source, while the AMFG and TMFG treatments used feed mixed with 20% dried Awamori-pressed lees or dried Tofu lees. The groups were fed mixed feed (volume to provide 100 g/d increase in body weight twice a day (10:00, 16:00. The klein grass hay and water was given ad libitum. The hay intake was measured at 08:00 and 16:00. Body weight and size measurements were taken once a month. At the end of the experiment, a blood sample was drawn from the jugular vein of each animal. The DCP and TDN intakes in AMFG and TMFG showed no significant difference to the CFG. Cumulative measurements of growth in body weight, withers height, chest depth, chest girth, and hip width over the 10 mo period in the AMFG and TMFG were similar to the CFG. By contrast, cumulative growth in body length and hip height in the AMFG and TMFG tended to be larger than the CFG. Cumulative growth in chest width in the AMFG was

  1. On the linear programming bound for linear Lee codes.

    Science.gov (United States)

    Astola, Helena; Tabus, Ioan

    2016-01-01

    Based on an invariance-type property of the Lee-compositions of a linear Lee code, additional equality constraints can be introduced to the linear programming problem of linear Lee codes. In this paper, we formulate this property in terms of an action of the multiplicative group of the field [Formula: see text] on the set of Lee-compositions. We show some useful properties of certain sums of Lee-numbers, which are the eigenvalues of the Lee association scheme, appearing in the linear programming problem of linear Lee codes. Using the additional equality constraints, we formulate the linear programming problem of linear Lee codes in a very compact form, leading to a fast execution, which allows to efficiently compute the bounds for large parameter values of the linear codes.

  2. Statistical study of some Lee galaxy groups

    Science.gov (United States)

    Mohamed, Sabry A.; Fouad, Ahmed M.

    2017-12-01

    Compact groups of galaxies are systems of small number of galaxies close to each other. They are a good laboratory to study galaxy properties, such as structure, morphology and evolution which are affected by the environment and galaxy interactions. We applied the tree clustering technique (the Euclidean separation distance coefficients) to test the physical reality of groups and used certain criteria (Sabry et al., 2009) depending on the physical attributes of the galaxies. The sample of the data is the quintets groups of Lee compact groups of galaxies (Lee et al., 2004). It is based on a modified version of Hickson's criteria (Hickson, 1982). The results reveal the membership of each galaxy and how it is related to its group. The tables of groups and their members are included. Our results indicates that 12 Groups are real groups with real members while 18 Groups have one galaxy that has attribute discordant and should be discarded from its group.

  3. Instability of the Lee-Wick bounce

    International Nuclear Information System (INIS)

    Karouby, Johanna; Brandenberger, Robert; Qiu, Taotao

    2011-01-01

    It was recently realized [Y. F. Cai, T. t. Qiu, R. Brandenberger, and X. m. Zhang, Phys. Rev. D 80, 023511 (2009).] that a model constructed from a Lee-Wick type scalar field theory yields, at the level of homogeneous and isotropic background cosmology, a bouncing cosmology. However, bouncing cosmologies induced by pressureless matter are in general unstable to the addition of relativistic matter (i.e. radiation). Here we study the possibility of obtaining a bouncing cosmology if we add radiation coupled to the Lee-Wick scalar field. This coupling in principle would allow the energy to flow from radiation to matter, thus providing a drain for the radiation energy. However, we find that it takes an extremely unlikely fine-tuning of the initial phases of the field configurations for a sufficient amount of radiative energy to flow into matter. For general initial conditions, the evolution leads to a singularity rather than a smooth bounce.

  4. Lipid composition of lees from Sherry wine.

    Science.gov (United States)

    Gómez, Maria Ester; Igartuburu, José M; Pando, Enrique; Luis, Francisco Rodríguez; Mourente, Gabriel

    2004-07-28

    In this paper, we describe the study and characterization of the lipids from lees of Sherry wine, one of the main byproducts from the wine-making industry in the Jerez/Xeres/Sherry denomination of the origin zone in Jerez de la Frontera, Spain. The lipid content, extractability, classification, fatty acid composition, and its main chemical characteristics have been determined in order to evaluate their potential use as a food or food additive. Copyright 2004 American Chemical Society

  5. Seroprevalence des anticorps anti-HBc chez les donneurs de sang ...

    African Journals Online (AJOL)

    'hépatite virale demeure une priorité pour les centres de qualification des produits sanguins labiles au Togo. Objectif: Déterminer la séroprévalence des anticorps anti-HBc au sein des donneurs de sang en vue d'estimer le niveau de risque ...

  6. Statistical study of some Lee galaxy groups

    Directory of Open Access Journals (Sweden)

    Sabry A. Mohamed

    2017-12-01

    Full Text Available Compact groups of galaxies are systems of small number of galaxies close to each other. They are a good laboratory to study galaxy properties, such as structure, morphology and evolution which are affected by the environment and galaxy interactions. We applied the tree clustering technique (the Euclidean separation distance coefficients to test the physical reality of groups and used certain criteria (Sabry et al., 2009 depending on the physical attributes of the galaxies. The sample of the data is the quintets groups of Lee compact groups of galaxies (Lee et al., 2004. It is based on a modified version of Hickson’s criteria (Hickson, 1982. The results reveal the membership of each galaxy and how it is related to its group. The tables of groups and their members are included.Our results indicates that 12 Groups are real groups with real members while 18 Groups have one galaxy that has attribute discordant and should be discarded from its group. Keywords: Galaxies, Cluster analysis, Galaxy groups, Lee galaxy groups

  7. Application des spots de sang séché en pharmacologie et en toxicologie

    OpenAIRE

    Deglon, Julien

    2012-01-01

    Dans le domaine de l’analyse biomédicale, le sang est de loin la matrice la plus couramment utilisée. Son obtention s’effectue traditionnellement par une ponction veineuse au niveau du bras. Un mode de prélèvement alternatif a fait son apparition dans les années 60 : les spots de sang séché sur papier filtre ou dried blood spots (DBS). Bien que les avantages (simplicité, micro volumes, transport, stockage et sécurité) aient été clairement identifiés, ce mode de prélèvements est longtemps rest...

  8. Grupos sangüíneos humanos nos livros didáticos de biologia

    OpenAIRE

    Pschisky, Alcionete

    2003-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Programa de Pós-Graduação em Educação. O trabalho apresenta a análise do tema Grupos Sangüíneos nos livros didáticos de Biologia dos últimos 40 anos. Foram identificados 24 assuntos que mostram como a temática Grupos Sangüíneos, está sendo veiculada ao longo dos anos, com especial atenção às questões de saúde humana. A presença e a profundidade de tais assuntos oscilam nas obras examinadas. O t...

  9. Negative effect of discharging vinification lees on soils.

    Science.gov (United States)

    Moldes, Ana B; Vázquez, Manuel; Domínguez, José M; Díaz-Fierros, Francisco; Barral, María T

    2008-09-01

    In this work, vinification lees from Galicia (Spain) were chemically analysed and compared with the composition of vinification lees from other regions and residues. Moreover, vinification lees were submitted to biological test employing cress, spring barley and ryegrass seeds. The evaluated vinification lees were rich in nutrients that are essential for plants, like P (2,520 mg kg(-1)), K (36,738 mg kg(-1)) and Mg (462 mg kg(-1)), but have low pH (3.9) and high C/N ratio. However, when vinification lees were submitted to biological tests, no germination was observed for garden cress and ryegrass seeds and almost no germination for spring barley seeds, showing the negative effect of discharging lees on crop fields.

  10. Sulfuric acid dissolution of the Chashma-Sang deposit's green clays

    International Nuclear Information System (INIS)

    Mirzoev, D.Kh.; Boboev, Kh.E.; Pulatov, M.S.; Mirsaidov, U.M.

    2005-01-01

    Present article is presenting the results of the roentgen phase, thermodynamic and physical-chemical investigations of the green clays of the Chashma-Sang deposit of the Republic of Tajikistan. It is presented mineralogical and chemical composition of the mineral raw materials. Kinetic of decomposition of the oxides of aluminum and iron on temperature, time and concentration of the sulfuric acid has been investigated

  11. Profil épidémiologique et séroprévalence des donneurs de sang ...

    African Journals Online (AJOL)

    Cette étude a pour objectif de déterminer le profil épidémiologique et sérologique des donneurs de sang aux Cliniques Universitaires de Lubumbashi. Méthodes: Il s'agit d'une étude descriptive transversale effectuée chez les donneurs de sang au cours d'une période de 6 mois soit de Janvier à Juin 2015 aux Cliniques ...

  12. Digital Preservation of the Quon Sang Lung Laundry Building, Fort Macleod, Alberta

    Science.gov (United States)

    Dawson, P.; Baradaran, F.; Jahraus, A.; Rubalcava, E.; Farrokhi, A.; Robinson, C.

    2017-08-01

    This paper describes the results of an emergency recording and archiving of a historic structure in Southern Alberta and explores the lessons learned. Digital recording of the Quon Sang Lung Laundry building in Fort Macleod, Alberta, was a joint initiative between Alberta Culture and Tourism and the University of Calgary. The Quon Sang Lung Laundry was a boomtown-style wood structure situated in the Fort Macleod Provincial Historic Area, Alberta. Built in the mid-1800s, the structure was one of the four buildings comprising Fort Macleod's Chinatown. Its association with Chinese immigration, settlement, and emergence of Chinese-owned businesses in early twentieth-century Alberta, made the Quon Sang Lung Laundry a unique and very significant historic resource. In recent years, a condition assessment of the structure indicated that the building was not safe and that the extent of the instability could lead to a sudden collapse. In response, Alberta Culture and Tourism engaged the Departments of Anthropology and Archaeology and Geomatics Engineering from the University of Calgary, to digitally preserve the laundry building. A complete survey including the laser scanning of all the remaining elements of the original structure, was undertaken. Through digital modeling, the work guarantees that a three-dimensional representation of the building is available for future use. This includes accurate 3D renders of the exterior and interior spaces and a collection of architectural drawings comprising floor plans, sections, and elevations.

  13. Retrospective: Ivy Lee and the German Dye Trust.

    Science.gov (United States)

    Hainsworth, Brad E.

    1987-01-01

    Examines the relationship between public relations trailblazer Ivy Lee and the German Dye Trust, which became an agent for the policies of Adolf Hitler. Discusses how Lee's efforts to use this relationship to persuade his contacts to influence the Nazi leadership failed because of his formal connection with this group. (JD)

  14. Tim Berners-Lee and Kofi Annan during the WSIS

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  15. Tim Berners-Lee and Kofi Annan during the WSIS

    CERN Document Server

    Patrice Loïez

    2003-01-01

    During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee, W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  16. Complete synchronization of two Chen-Lee systems

    International Nuclear Information System (INIS)

    Sheu, L-J; Chen, J-H; Chen, H-K; Tam, L-M; Lao, S-K; Chen, W-C; Lin, K-T

    2008-01-01

    This study demonstrates that complete synchronization of two Chen-Lee chaotic systems can be easily achieved. The upper bound of the Chen-Lee chaotic system is estimated numerically. A controller is designed to synchronize two chaotic systems. Sufficient conditions for synchronization are obtained using Lyapunov's direct method. Two numerical examples are presented to verify the proposed synchronization approach

  17. Web Inventor Berners-Lee starts a Blog

    CERN Document Server

    Olson, Parmy

    2005-01-01

    Berners-Lee created what is known today as the World Wide Web. Now, just in time for the Web's 15th anniversary and after taking his proverbial stroll around the global dwelling of cyberspace, Berners-Lee is chatting with the rest of us about what he thinks with a blog

  18. Tim Berners-Lee receives the Millennium Technology Prize

    CERN Multimedia

    2004-01-01

    On 15 April, for his invention of the Web, Tim Berners-Lee was awarded the first ever Millennium Technology Prize by the Finnish Technology Award Foundation, which recognises technological innovations of lasting benefit to society. "Tim Berners-Lee's invention perfectly encapsulates the spirit of the Prize. The Web is encouraging new types of social networks, contributing to transparency and democracy, and opening up new avenues for information management and business development," underlined Pekka Tarjanne, chairman of the jury and former Secretary-General of the International Telecommunication Union (ITU). Tim Berners-Lee is congratulated by Jukka Valtasaari, Finland's Ambassador to the United States. Tim Berners-Lee created the first server, browser and editor, the HTML code, the URL address and the HTTP transmission protocol at CERN in 1990. CERN released the Web into the public domain in 1993. Tim Berners-Lee is currently head of the World Wide Web Consortium, managed by ERCIM (Europe...

  19. Thermodynamics of the Lee-Wick partners: An alternative approach

    International Nuclear Information System (INIS)

    Bhattacharya, Kaushik; Das, Suratna

    2011-01-01

    It was pointed out some time ago that there can be two variations in which the divergences of a quantum field theory can be tamed using the ideas presented by Lee and Wick. In one variation the Lee-Wick partners of the normal fields live in an indefinite metric Hilbert space but have positive energy and in the other variation the Lee-Wick partners can live in a normal Hilbert space but carry negative energy. Quantum mechanically the two variations mainly differ in the way the fields are quantized. In this article the second variation of Lee and Wick's idea is discussed. Using statistical mechanical methods the energy density, pressure and entropy density of the negative energy Lee-Wick fields have been calculated. The results exactly match with the thermodynamic results of the conventional, positive energy Lee-Wick fields. The result sheds some light on the second variation of Lee-Wick's idea. The result seems to say that the thermodynamics of the theories do not care about the way they are quantized.

  20. Constraints on the Lee-Wick Higgs sector

    International Nuclear Information System (INIS)

    Carone, Christopher D.; Primulando, Reinard

    2009-01-01

    Lee-Wick partners to the standard model Higgs doublet may appear at a mass scale that is significantly lower than that of the remaining Lee-Wick partner states. The relevant effective theory is a two-Higgs doublet model in which one doublet has wrong-sign kinetic and mass terms. We determine bounds on this effective theory, including those from neutral B-meson mixing, b→X s γ, and Z→bb. The results differ from those of conventional two-Higgs doublet models and lead to meaningful constraints on the Lee-Wick Higgs sector.

  1. STUDI SEMIOTIK SIKAP HUMANIS-RELIGIUS DALAM TRAILER FILM SANG MURABBI

    Directory of Open Access Journals (Sweden)

    Eli Purwati

    2016-02-01

    Full Text Available Film Indonesia sekarang ini adalah kelanjutan dari tradisi tontonan rakyat sejak masa tradisional, dan masa penjajahan sampai masa kemerdekaan. Untuk meningkatkan apresiasi penonton film Indonesia adalah dengan menyempurnakan permainan trik- trik serealistis dan sehalus mungkin, seni akting yang lebih nyata, pembenahan struktur cerita, pembenahan setting budaya yang lebih dapat dipertanggung jawabkan, penyuguhan gambar yang lebih estetis dan sebagainya. Dalam perkembangannya film tidak hanya dijadikan sebagai media hiburan semata tetapi juga digunakan sebagai alat propaganda, terutama menyangkut tujuan sosial atau nasional. Dari pemaparan di atasa maka peneliti mengambl judul :Bagaimanakah peran sikap humanis-religius ustadz direpresentasikan dalam trailer film Sang Murabbi? Metode yang digunakan pada penelitian ini adalah metode analisis semiotika. Semiotika melihat teks media sebagai sebuah struktur secara keseluruhan. Objek dalam penelitian ini adalah trailer film Sang Murabbi yang dirilis pada tahun 2008, dan disutradarai oleh Zul Ardhia. Film ini menceritakan kehidupan Almarhum KH Rahmat Abdullah (1953-2005, seorang ustadz yang berasal dari Betawi atau Jakarta. Sedangkan pemeran dalam film ini antara lain: Sutan Reinaldy, Astri Ivo, Aty Cancer, Neno Warisman, Jerrio Jeffry, Benny Riswandi, dan David Chalik. Dapat disimpulkan bahwa Representasi sikap humanis-religius ustadz dalam film ini tampak dari kesederhanaan serta keseharian dari Ustadz Rahmat. Misalnya ketika beliau kesulitan uang, atau ketika beliau tetap melakukan kegiatan domestic seperti menyapu halaman rumahnya. Dan Sikap kemanusiaan dari Ustadz Rahmat tertera dalam adegan kepedulian membantu umat serta memikirkan umat, baik dengan materi, rohani, maupun pendidikan.

  2. Blood group genotyping Genotipagem de grupos sangüíneos

    Directory of Open Access Journals (Sweden)

    Lilian Castilho

    2004-01-01

    Full Text Available Accurate phenotyping of red blood cells (RBCs can be difficult in transfusion-dependent patients such as those with thalassemia and sickle cells anemia because of the presence of previously transfused RBCs in the patient's circulation. Recently, the molecular basis associated with the expression of many blood group antigens was established. This allowed the development of a plethora of polymerase chain reaction-based tests for identification of the blood group antigens by testing DNA. The determination of blood group polymorphism at the genomic level facilitates the resolution of clinical problems that cannot be addressed by hemagglutination. They are useful to (a determine antigen types for which currently available antibodies are weakly reactive; (b type patients who have been recently transfused; (c identify fetuses at risk for hemolytic disease of the newborn; and (d to increase the reliability of repositories of antigen negative RBCs for transfusion. It is important to note that PCR based assays are prone to different types of errors that those observed with hemagglutination assays. For instance, contamination with amplified products may lead to false positive test results. In addition, the identification of a particular genotype does not necessarily mean that the antigen will be expressed on the RBC membrane.Os antígenos eritrocitários são herdados geneticamente e definidos por seqüências de aminoácidos específicos constituindo uma proteína ou por carboidratos ligados a estas proteínas ou à lipídios. A diversidade dos antígenos de grupos sangüíneos, como para qualquer outro traço biológico, encontra-se ao nível do gene. Existem atualmente mais de 250 antígenos eritrocitários que se encontram distribuídos em 29 sistemas de grupos sangüíneos, de acordo com a Nomenclatura da Sociedade Internacional de Transfusão Sangüínea (ISBT. Os genes que codificam 28 dos 29 sistemas de grupos sangüíneos já foram clonados e seq

  3. La conservation autologue de sang de cordon ombilical : vers une nouvelle forme de participation biocitoyenne ?

    Directory of Open Access Journals (Sweden)

    Anouck Alary

    2016-09-01

    Full Text Available La transformation du sang placentaire en une précieuse source de cellules souches a donné naissance à partir des années 1990 à une industrie globale de conservation de sang de cordon ombilical faisant désormais concurrence à un large réseau de banques publiques de sang de cordon. Cet article explore les soubassements socioculturels liés à l’émergence de cette industrie et tente d’élucider les enjeux éthiques et politiques qu’elle pose. Si les banques publiques de sang de cordon sont porteuses des valeurs d’altruisme et de solidarité nationale traditionnellement liées au modèle redistributif d’échange de sang et d’organes né après la Seconde Guerre mondiale, les banques privées renvoient, elles, à des formes de solidarité bien différentes. C’est effectivement sous couvert de la solidarité familiale et de la responsabilité morale des mères de protéger leurs enfants qu’elles définissent la conservation privée comme une forme d’ « assurance biologique » contre les risques à la santé de l’enfant. En permettant aux mères d’investir leurs tissus corporels à la fois dans le futur incertain de leurs enfants et dans des thérapies cellulaires expérimentales, ces banques promeuvent un nouveau modèle de participation du/de la patient.e à la coconstitution de futures innovations thérapeutiques. Nous inscrivons ce modèle de participation dans les reconfigurations contemporaines du biopolitique que le sociologue britannique Nikolas Rose (2007 voit s’incarner dans l’émergence d’une nouvelle forme de biocitoyenneté. L’article critique finalement ces services personnalisés en soulignant qu’ils ont le potentiel d’opérer de nouvelles formes de coercition sur les mères, dans un contexte sociopolitique caractérisé par une responsabilisation accrue des individus au regard de la « bonne gestion » de leurs risques à la santé. Ces services sont aussi jugés problématiques sur le plan

  4. General Robert E. Lee -- Brightest Star in the South

    National Research Council Canada - National Science Library

    Dalton, Kent B

    2006-01-01

    .... Lee's distinctive application of operational art and leadership as the commander of the Army of Northern Virginia, we can discern many lessons which are still pertinent to our commanders at the operational level today...

  5. The Statecraft of Lee Kuan Yew, Visionary and Opportunist

    National Research Council Canada - National Science Library

    Thomas, David

    1996-01-01

    ...." "Not so," replied the passenger, Lee Kuan Yew, "Singapore intends to continue to ride along as part of the federation created with Malaysia, Sarawak, and Sabah -- we have no plans for getting off...

  6. Nobel laureate T.D. Lee at CERN

    CERN Multimedia

    2007-01-01

    On 30 August, Professor T.D. Lee, who received the Nobel Prize for Physics in 1957, gave a seminar at CERN on symmetry and asymmetry in electroweak interactions, 50 years after the discovery of the non-conservation of parity. In 1956, Tsung-Dao Lee postulated with Chen Ning Yang that parity is not conserved in weak interactions, and suggested several experiments to demonstrate this. The following year, an experiment led by Chien-Shiung Wu proved this prediction and, soon after, T.D. Lee and Chen Ning Yang were awarded the Nobel Prize for Physics. Still very active at over 80 years of age, T.D. Lee pursues his theory work to this day.

  7. [Status of diagnosis and treatment devices of acupuncture based on SooPAT and bibliometrics in China].

    Science.gov (United States)

    Bai, Lin; Ren, Yulan; Guo, Taipin; Chen, Lin; Zhou, Yumei; Feng, Shuwei; Li, Ji; Liang, Fanrong

    2016-11-12

    To perform a bibliometrics analysis on patent literature regarding diagnosis and treatment devices of acupuncture in China, aiming to provide references for the development of diagnosis and treatment devices of acupuncture. Based on SooPAT, a patent database, the patent literature regarding diagnosis and treatment devices of acupuncture in China was collected. With bibliometrics methods, the annual distribution of type, quantity, classification and content of diagnosis and treatment devices of acupuncture were analyzed. The number of acupuncture diagnosis and treatment devices reached its peak in 2012 and 2013 in China. The A61N in patent and utility model patent were the most, which were mainly related to electrotherapy, magnetic therapy, radioactive therapy and ultrasound therapy, etc. The main content was acupuncture treatment devices and meridian treatment devices. The 24-01 in design patent was the most, involving fixation devices used by doctors, hospitals and laboratories, etc. Currently the majority of diagnosis and treatment devices of acupuncture is therapeutic apparatus, while the acupuncture diagnosis devices are needed.

  8. Kajian Aspek Fotografis dalam Tehnik Olah Digital Poster Film “ Sang Pemimpi ”

    Directory of Open Access Journals (Sweden)

    Noor Latif CM

    2011-04-01

    Full Text Available As the advancement of digital imaging technology, this urges internal actors to be more accurate and explorative in producing visual communication work with photography element and digital touching process. Digital process ability with no photographical ability will produce raw and anomaly visual work of art. Besides, audience is smarter and more appreciative towards quality of visual appearance in several modern communication media. Film poster of Sang Pemimpi is a case reflection of general digital in visual communication work that has gap among communication product content according to the brand of the film. Photography element composition is melted with bondless pile among the objects. Logical photography as bonding bridge of visual logic is weak in execution; where we could see it has less digital process commercial market need with the supporting resources. 

  9. Radiation bounce from the Lee-Wick construction?

    International Nuclear Information System (INIS)

    Karouby, Johanna; Brandenberger, Robert

    2010-01-01

    It was recently realized that matter modeled by the scalar field sector of the Lee-Wick standard model yields, in the context of a homogeneous and isotropic cosmological background, a bouncing cosmology. However, bouncing cosmologies induced by pressureless matter are in general unstable to the addition of relativistic matter (i.e. radiation). Here we study the possibility of obtaining a bouncing cosmology if we add not only radiation, but also its Lee-Wick partner, to the matter sector. We find that, in general, no bounce occurs. The only way to obtain a bounce is to choose initial conditions with very special phases of the radiation field and its Lee-Wick partner.

  10. Lee Acculturation Dream Scale for Korean-American college students.

    Science.gov (United States)

    Lee, Sang Bok

    2005-04-01

    This study examined acculturation as represented in dream narratives of 165 Korean immigrant college students living in the USA. A total of 165 dreams were collected and evaluated using the Lee Acculturation Dream Scale, for which locations of dream contents were coded. 39% of the dreams took place in South Korea, while 38% were in the USA. Also, 16% of the dreams included both locations, whereas 7% had no specific dream location. The dreams contained overlapping dream messages, images, scenes, and interactions in both South Korea and the USA. A two-sample t test on the mean scores of the Lee Acculturation Dream Scale indicated no significant difference between men and women.

  11. Lee-Wick indefinite metric quantization: A functional integral approach

    International Nuclear Information System (INIS)

    Boulware, D.G.; Gross, D.J.

    1984-01-01

    In an attempt to study the stability of the Lee-Wick indefinite metric theory, the functional integral for indefinite metric quantum field theories is derived. Theories with an indefinite classical energy may be quantized with either a normal metric and an indefinite energy in Minkowski space or an indefinite metric and a positive energy in euclidean space. However, the functional integral in the latter formulation does not incorporate the Lee-Wick prescription for assuring the unitarity of the positive energy positive metric sector of the theory, hence the stability of the theory cannot be studied non-perturbatively. (orig.)

  12. Lee de Forest King of Radio, Television, and Film

    CERN Document Server

    Adams, Mike

    2012-01-01

    Lee de Forest, Yale doctorate and Oscar winner, gave voice to the radio and the motion picture. Yet by the 1930s, after the radio and the Talkies were regular features of American life, Lee de Forest had seemingly lost everything. Why? Why didn’t he receive the recognition and acclaim he sought his entire life until years later in 1959, when he was awarded an Oscar? A lifelong innovator, Lee de Forest invented the three-element vacuum tube which he developed between 1906 and 1916 as a detector, amplifier, and oscillator of radio waves. As early as 1907, he was broadcasting music programming. In 1918, he began to develop a system for recording and playing back sound by using light patterns on motion picture film. In order to promote and demonstrate his process he made hundreds of short sound films, found theatres for their showing, and issued publicity to gain audiences for his invention. While he received many patents for this technology, he was ignored by the film industry. Lee de Forest, King of Radio, Te...

  13. Must Historians Regress? An Answer to Lee Benson.

    Science.gov (United States)

    Kousser, J. Morgan

    1986-01-01

    Considers the impact of empirical social science methodology and data analysis techniques on the process of historical analysis and its product, generalizations about the past. Uses political preference and voting information as a vehicle to illustrate the differences in historical conclusions reached by Lee Benson and J. Morgan Kousser. (JDH)

  14. The Garrett Lee Smith Memorial Suicide Prevention Program

    Science.gov (United States)

    Goldston, David B.; Walrath, Christine M.; McKeon, Richard; Puddy, Richard W.; Lubell, Keri M.; Potter, Lloyd B.; Rodi, Michael S.

    2010-01-01

    In response to calls for greater efforts to reduce youth suicide, the Garrett Lee Smith (GLS) Memorial Act has provided funding for 68 state, territory, and tribal community grants, and 74 college campus grants for suicide prevention efforts. Suicide prevention activities supported by GLS grantees have included education, training programs…

  15. Sieve bootstrapping in the Lee-Carter model

    NARCIS (Netherlands)

    Heinemann, A.

    2013-01-01

    This paper studies an alternative approach to construct confidence intervals for parameter estimates of the Lee-Carter model. First, the procedure of obtaining confidence intervals using regular nonparametric i.i.d. bootstrap is specified. Empirical evidence seems to invalidate this approach as it

  16. Robert E. Lee, George Peabody, and Sectional Reunion.

    Science.gov (United States)

    Parker, Franklin

    1994-01-01

    Discusses an 1869 meeting between George Peabody, educational philanthropist, and Robert E. Lee. The meeting focused public attention on the Peabody Education Fund and the South's educational plight. Significant measures of educational efforts in the South are directly attributable to several informal meetings centered around Peabody and Lee…

  17. Rejoinder to Goldberg, Lee and Ashton : Explaining counterintuitive findings

    NARCIS (Netherlands)

    Anderson, N.; Ones, D.S.

    2008-01-01

    In their critique of our erratum and addendum (Anderson & Ones, [2008]), Goldberg, Lee, and Ashton ([2008]) allege clerical errors (1) where participants' HPI scores were incorrectly matched to other inventory scale scores and (2) in scoring of the OPQ and BPI scales. The first point was fully

  18. W3C head Berners-Lee to be knighted

    CERN Multimedia

    Gross, G

    2004-01-01

    "Tim Berners-Lee, credited with inventing the World Wide Web and now director of the World Wide Web Consortium, will be named a knight commander, Order of the British Empire, by Queen Elizabeth II, the W3C announced Wednesday" (1 page)

  19. Virginia Lee Burton's "Little House" in Popular Consciousness

    DEFF Research Database (Denmark)

    Goddard, Joseph

    2011-01-01

    This article considers the significance of Victoria Lee Burton’s authorship, specifically The Little House, for lifestyle preferences and the development of environmental consciousness in the postwar period. The article argues that Burton deliberately designed her work to evoke country-friendly s...

  20. Berners-Lee wins inaugural Millennium Technology prize

    CERN Multimedia

    2004-01-01

    "World Wide Web inventor Tim Berners-Lee today was named recipient of the first-ever Millennium Technology Prize. The honor, which is accompanied by one million euros, is bestowed by the Finnish Technology Award Foundation as an international acknowledgement of outstanding technological innovation aimed at promoting quality of life and sustainable economic and societal development" (1 page)

  1. Tim Berners-Lee, World Wide Web inventor

    CERN Document Server

    1998-01-01

    The "Internet, Web, What's next?" conference on 26 June 1998 at CERN: Tim Berners-Lee, inventor of the World Wide Web and Director of the W3C, explains how the Web came to be and gave his views on the future.

  2. Dan Gilmor Column [Berners-Lee and the WWW

    CERN Multimedia

    Gillmore, D

    2002-01-01

    In the keynote speech at the 11th Annual World Wide Web Conference, Tim Berner's Lee said that in the early days of the web, people were worrying about the same thing as today - one company dominating the market and controlling standards (2 pages).

  3. Controverses institutionnelles et sociales autour du sang placentaire recueilli à des fins thérapeutiques1

    OpenAIRE

    Boileau, Claire

    2003-01-01

    Dans cet article, nous proposons d’exposer les résultats d’une recherche en anthropologie sociale et culturelle portant sur les enjeux du prélèvement de sang placentaire. Ce sang, riche en cellules souches, est prélevé au moment de l’accouchement sur des femmes ayant consenti au don. Il est ensuite traité puis stocké en attendant d’être greffé à des patients leucémiques. Appelé à se développer dans les années à venir, le prélèvement de cellules souches rencontre des difficultés de recueil non...

  4. Diversity, threats and conservation of catfish fauna of the Krishna River, Sangli District, Maharashtra, India

    Directory of Open Access Journals (Sweden)

    S.M. Kumbar

    2014-01-01

    Full Text Available The diversity of freshwater catfish species of the Krishna River, Sangli District was studied from June 2009 to July 2012. The study area covered 105km from Karad City where the Koyna tributary joins the Krishna River up to Mhaishal, the state border of Maharashtra. It was divided into three streams for convenience, i.e., the upper stream starts from Karad and goes up to Takari, the middle stream from Takari to Bhilawadi and downstream from Bhilawadi to Mhaishal. A total of 13 species of catfish belonging to five families and 10 genera were recorded. The Bagridae family was dominant with six species, whereas Siluridae, Schilbidae and Clariidae had two species each and Sisoridae with one species. We have provided range extension for an endemic and threatened sisorid catfish Glyptothorax poonaensis. The occurrence and distribution of catfishes was more or less equal in number along the study area. The maximum number of species recorded was nine from the upper stream, whereas the middle and down streams had eight and seven species respectively. The distribution of catfish along the Krishna River system may be due to the slow and steady state water movement and its width that ensure the continuous availability of nutrition. It is suggested that the Krishna River would be a suitable habitat for the conservation of freshwater catfish if the threats are minimized.

  5. Nooruslikud juubilarid: fotokelder Lee 20 ja fotomuuseum 30 / Mall Parmas, Betty Ester-Väljaots

    Index Scriptorium Estoniae

    Parmas, Mall

    2013-01-01

    Peeter Toominga algatusel 1992. aastal asutatud Lee fotokeldrist. Loetletud fotomuuseumis oma töid eksponeerinud fotograafid. Ülevaatenäitus "Lee fotokelder 20" 17. jaanuarist 20. märtsini, koostaja Betty Ester-Väljaots

  6. Vafa-Witten theorem and Lee-Yang singularities

    International Nuclear Information System (INIS)

    Aguado, M.; Asorey, M.

    2009-01-01

    We prove the analyticity of the finite volume QCD partition function for complex values of the θ-vacuum parameter. The absence of singularities different from Lee-Yang zeros only permits and cusp singularities in the vacuum energy density and never or cusps. This fact together with the Vafa-Witten diamagnetic inequality implies the vanishing of the density of Lee-Yang zeros at θ=0 and has an important consequence: the absence of a first order phase transition at θ=0. The result provides a key missing link in the Vafa-Witten proof of parity symmetry conservation in vectorlike gauge theories and follows from renormalizability, unitarity, positivity, and existence of Bogomol'nyi-Prasad-Sommerfield bounds. Generalizations of this theorem to other physical systems are also discussed, with particular interest focused on the nonlinear CP N sigma model.

  7. Lee Miller, une battante sur tous les fronts

    Directory of Open Access Journals (Sweden)

    Anaïs Boutot

    2009-06-01

    Full Text Available L’art photographique de Lee Miller, à l’image de sa vie, revêt de multiples facettes. Après avoir été devant l’objectif en tant que mannequin puis égérie du Paris surréaliste, elle passe derrière l’objectif pour devenir photographe de mode, reporter de guerre ou encore portraitiste. L’exposition L’Art de Lee Miller, présentée au Jeu de Paume du 21 octobre 2008 au 4 janvier 2009 et accompagnée d’un ouvrage paru en français chez Hazan mettait en avant une quête d’identité et d’indépendance qui ...

  8. Economist Innovation Award for Tim Berners-Lee

    CERN Multimedia

    2003-01-01

    In September, Tim Berners-Lee, who invented the World Wide Web at CERN and is now Director of the W3C World Wide Web Consortium, received the 2nd Economist Annual Innovation Award in Computing. With the award The Economist, a British weekly newspaper, recognises individuals responsible for breakthroughs in Bioscience, Computing, Energy and the Environment, and Telecommunications that have a profound impact on industry. A fifth award is given in a special "No Boundaries" category, observing innovation that transcends industries. Candidates for the awards are proposed by The Economist readers and writers, and by a group of judges. Tim Berners-Lee received the Computing award for his global hypertext project, to be known as the World Wide Web, which "forever altered the way information is shared" and is a huge contribution to the efficiency of the scientific community. Based on a programme for storing information using random associations called "Enquire", it...

  9. What Lee Raymond actually said in Beijing [15th WPC

    International Nuclear Information System (INIS)

    Raymond, Lee.

    1997-01-01

    When Lee Raymond, Chairman and Chief Executive Officer, Exxon Corporation gave this keynote address at the recent World Petroleum Congress in Beijing, he drew attention to the way economic growth alleviates poverty and to the close linkage between economic growth and energy use. He also drew attention to the weakness of the scientific evidence for climate change being caused by fossil fuel burning and his doubts about the wisdom of setting targets for the reduction of CO 2 emissions. At a press conference after the presentation Lee Raymond assented to the suggestion that the European oil companies have been hijacked by the environmentalists. Petroleum Review has reproduced the full text of the speech so that readers can judge for themselves the merits of the arguments and their likely impact on the Kyoto conference. (UK)

  10. Fate of grape flavor precursors during storage on yeast lees.

    Science.gov (United States)

    Loscos, Natalia; Hernández-Orte, Purificación; Cacho, Juan; Ferreira, Vicente

    2009-06-24

    The effect of the addition of a grape flavor precursor extract to a grape juice, before or after fermentation with three different Saccharomyces cerevisiae yeast strains, on the evolution of the wine aroma composition during a 9-month aging period on yeast lees has been studied. Wine aroma compounds were determined by gas chromatography-mass spectrometry after alcoholic fermentation and after 3 and 9 months of storage. The aging of wine on lees caused important changes in the aroma profiles of wines, making the concentrations of three terpenes, norisoprenoids (except beta-damascenone and beta-ionone), 4-allyl-2,6-dimethoxyphenol, ethyl vanillate, syringaldehyde, and ethyl cinnamate increase, whereas the concentrations of most of the rest of compounds tended to decrease. Lees are responsible for the observed increasing trends, except for linalool and alpha-terpineol, and also for a large part of the observed decrements. As expected, the addition of precursors brings about an increment in the levels of most terpenes, norisoprenoids, vanillins, and ethyl cinnamate, and it is after an aging time when differences linked to the level of precursors in the must become more evident. The timing of the addition of precursors has a minor influence, except for beta-damascenone, vanillin, and syringaldehyde, for which supplementation after fermentation is more effective. It has also been observed that the precursor fraction makes the levels of vinylphenols decrease. Finally, it has also been found that lees from different yeast strains may have a slightly different abilities to release volatile compounds derived from precursors.

  11. Gettysburg: A Study of Lee’s Command Effectiveness, 1863

    Science.gov (United States)

    2011-03-21

    scholar of military history it is not necessary to focus strictly on the tactics of a single battle, or campaign, or even an entire war. To fully...the second day was the Peach Orchard and ultimately Cemetery Hill.48 The Peach Orchard was carried at a heavy cost but attacks on Little Round Top...Union troops to occupy the desired ground of the Peach Orchard and obtain positions on Little Round Top. Knowing Longstreet’s nature, Lee did not

  12. Tim Berners-Lee, World Wide Web inventor

    CERN Document Server

    1994-01-01

    Former physicist, Tim Berners-Lee invented the World Wide Web as an essential tool for high energy physics at CERN from 1989 to 1994. Together with a small team he conceived HTML, http, URLs, and put up the first server and the first 'what you see is what you get' browser and html editor. Tim is now Director of the Web Consortium W3C, the International Web standards body based at INRIA, MIT and Keio University.

  13. Triniti daripada Perspektif Taoisme: Analisis Pemikiran Jung Young Lee

    Directory of Open Access Journals (Sweden)

    ZURAIZA HUSIN

    2016-06-01

    Full Text Available Jung Young Lee is a Korean-born theologian who employs creatively the doctrine of the Trinity from an Asian worldview. This article aims to analyze Lee’s approaches of the Trinity with the Yin-Yang symbolism. The main reference is based on the book written by him entitled ‘The Trinity in Asian Perspective (1996’. Lee has turned his attention to the topic of Trinity through the lens of the culture and thought patterns of his own milieu. One of the leading point in presenting Yin-Yang principle as Trinitarian thinking, Lee examines the interpretation of the term “in” in the Bible, "Believe me that I am in the Father and the Father is in me" (John 14:11. The statement leads to the point that Yin and Yang cannot exist without each other because relationality is given priority than individuality. The idea is based on the terminology of ‘both/and’. So, ‘and’ indicates a Trinitarian statement, there is interdependence and unification. With reference to Trinity, the Father and the Son are One because of ‘and’. In addition, the same concept implements to the Holy Spirit. Lee views ‘and’ is not only a linking principle in both-and thinking but also the principle that is ‘between’ two. When ‘two’ exists, the third also exist between them. Based on the idea of ‘middle’, represents the connecting element between two, which contributes for the existence of the Third. Accordingly, the Spirit is the third element in the Trinity relationship.

  14. PEMBERIAN BONUS KEPADA PEKERJA DI PT. SANG HYANG SERI (PERSERO DALAM RANGKA MENINGKATKAN PRODUKTIVITAS KERJA DITINJAU DARI UNDANG-UNDANG NOMOR 13 TAHUN 2003 TENTANG KETENAGAKERJAAN

    Directory of Open Access Journals (Sweden)

    Rani Apriani, S.E., S.H., M.H.

    2016-05-01

    Full Text Available Workers primary motivation to do a job is to earn wages as agreed on the contract, but sometimes, the wages has some issue, one of which is when thethe worker felt that they already produce the job exceed the standard worker. Bonus classified as non-wage income provided by the company in order to encourage workers to be more discipline, industrious, productive, and increase the workers earning in PT. Sang Hyang Seri. The purpose of this research was to examine the rule used by PT. Sang Hyang Seri when giving bonuses to increase productivity and to examine the bonus implementation in PT. Sang Hyang Seri comply with Act Number 3 on 2013 related with employment.

  15. Phenolic characterization of aging wine lees: Correlation with antioxidant activities.

    Science.gov (United States)

    Romero-Díez, R; Rodríguez-Rojo, S; Cocero, M J; Duarte, C M M; Matias, A A; Bronze, M R

    2018-09-01

    Aging wine lees are water-wastes produced during the wine aging inside wood barrels that can be considered as alternative sources of bioactive compounds. Phenolic characterization and antioxidant activity (AA) measurements of wines lees solid-liquid extracts have been undertaken on a dry extract (DE) basis. Solvents with different polarities (water, methanol, ethanol, two hydroalcoholic mixtures and acetone) were used. Total phenolic (TPC) and total flavonoid contents (TFC) were determined. The mixture of 75:25(v/v) EtOH:H 2 O showed the highest values with 254 mg GAE /g DE and 146 mg CATE /g DE respectively. HORAC, HOSC and FRAP were used to determine the AA of the extracts being also highest for the mixture of 75:25(v/v) EtOH:H 2 O (4690 µmol CAE /g DE , 4527 µmol TE /g DE and 2197 µmol TE /g DE , respectively). For ORAC method, methanol extract showed the best value with 2771 µmol TE /g DE . Correlations between TPC, TFC, phenolic compounds and AA were determined. Most relevant compounds contributing to AA were identified using data from mass spectrometry, being mainly anthocyanins. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. T.D Lee and Lisa Randall visit ATLAS

    CERN Multimedia

    Pauline Gagnon

    Professor Tsung-Dao Lee, who received the Nobel Prize for Physics in 1957 for postulating that parity is not conserved in weak interactions, visited the ATLAS detector this month. He is seen here in the company of Peter Jenni, spokesperson for ATLAS. T.D. Lee is still very active at over 80, pursuing his theory work to this day. Professor Lisa Randall from Harvard University, the well-known theorist behind the Randall-Sundrum theory for extra dimensions, was also part of the group visiting the ATLAS detector. She is seen here with Fabiola Gianotti, deputy spokesperson for ATLAS. Lisa Randall's two initial papers have been quoted both more than 2500 times, making her the most cited theoretical physicist in the world in the last five years as of last autumn - a total of about 10,000 citations! One wonders here if Peter is pointing to a CP-violating graviton spotted in the ATLAS cavern... From left to right: Fabiola Gianotti, Gustaaf Brooijmans, convener of the ATLAS Exotics physics gro...

  17. Robert E. Lee as Operational Artist During the American Civil War

    Science.gov (United States)

    2010-04-21

    Johnston was just as arrogant as Davis. During his tenure as a student at the United States Military Academy Johnston eamed the nickname "Colonel" from his...shown previous subordinate leaders .. Lee had certainly eamed it based on his reputation and performance at Second Manassas and during his tenure as...Washington, PA: EasternNational. Roland, Charles P. 1964. The Generalship of Robert E. Lee. In Grant, Lee, Lincoln and The Radicals; Essays on

  18. Wrong vertex displacements due to Lee-Wick resonances at LHC

    International Nuclear Information System (INIS)

    Alvarez, E.; Schat, C.; Rold, L. da; Szynkman, A.

    2009-01-01

    We show how a resonance from the recently proposed Lee-Wick Standard Model could lead to wrong vertex displacements at LHCb. We study which could be the possible 'longest lived' Lee-Wick particle that could be created at LHC, and we study its possible decays and detections. We conclude that there is a region in the parameter space which would give wrong vertex displacements as a unique signature of the Lee-Wick Standard Model at LHCb. Further numerical simulation shows that LHC era could explore these wrong vertex displacements through Lee-Wick leptons below 500 GeV. (author)

  19. The Friedberg-Lee symmetry and minimal seesaw model

    International Nuclear Information System (INIS)

    He Xiaogang; Liao Wei

    2009-01-01

    The Friedberg-Lee (FL) symmetry is generated by a transformation of a fermionic field q to q+ξz. This symmetry puts very restrictive constraints on allowed terms in a Lagrangian. Applying this symmetry to N fermionic fields, we find that the number of independent fields is reduced to N-1 if the fields have gauge interaction or the transformation is a local one. Using this property, we find that a seesaw model originally with three generations of left- and right-handed neutrinos, with the left-handed neutrinos unaffected but the right-handed neutrinos transformed under the local FL translation, is reduced to an effective theory of minimal seesaw which has only two right-handed neutrinos. The symmetry predicts that one of the light neutrino masses must be zero.

  20. Searching for Lee-Wick Gauge Bosons at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Rizzo, Thomas G.

    2007-04-30

    In an extension of the Standard Model(SM) based on the ideas of Lee and Wick, Grinstein, O'Connell and Wise have found an interesting way to remove the usual quadratically divergent contributions to the Higgs mass induced by radiative corrections. Phenomenologically, the model predicts the existence of Terascale, negative-norm copies of the usual SM fields with rather unique properties: ghost-like propagators and negative decay widths, but with otherwise SM-like couplings. The model is both unitary and causal on macroscopic scales. In this paper we examine whether or not such states with these unusual properties can be uniquely identified as such at the LHC. We find that in the extended strong and electroweak gauge boson sector of the model, which is the simplest one to analyze, such an identification can be rather difficult. Observation of heavy gluon-like resonances in the dijet channel offers the best hope for this identification.

  1. THE YUAN-TSEH LEE ARRAY FOR MICROWAVE BACKGROUND ANISOTROPY

    International Nuclear Information System (INIS)

    Ho, Paul T. P.; Altamirano, Pablo; Chang, C.-H.; Chang, S.-H.; Chang, S.-W.; Chen, C.-C.; Chen, K.-J.; Chen, M.-T.; Han, C.-C.; Ho, West M.; Huang, Y.-D.; Hwang, Y.-J.; Ibanez-Romano, Fabiola; Jiang Homin; Koch, Patrick M.; Kubo, Derek Y.; Li, C.-T.; Lim, Jeremy; Lin, K.-Y.; Liu, G.-C.

    2009-01-01

    The Yuan-Tseh Lee Array for microwave background anisotropy is the first interferometer dedicated to study the cosmic microwave background radiation at 3 mm wavelength. The choice of 3 mm is to minimize the contributions from foreground synchrotron radiation and Galactic dust emission. The initial configuration of seven 0.6 m telescopes mounted on a 6 m hexapod platform was dedicated in 2006 October on Mauna Loa, Hawaii. Scientific operations began with the detection of a number of clusters of galaxies via the thermal Sunyaev-Zel'dovich effect. We compare our data with Subaru weak-lensing data to study the structure of dark matter. We also compare our data with X-ray data to derive the Hubble constant.

  2. Perturbative unitarity of Lee-Wick quantum field theory

    Science.gov (United States)

    Anselmi, Damiano; Piva, Marco

    2017-08-01

    We study the perturbative unitarity of the Lee-Wick models, formulated as nonanalytically Wick rotated Euclidean theories. The complex energy plane is divided into disconnected regions and the values of a loop integral in the various regions are related to one another by a nonanalytic procedure. We show that the one-loop diagrams satisfy the expected, unitary cutting equations in each region: only the physical d.o.f. propagate through the cuts. The goal can be achieved by working in suitable subsets of each region and proving that the cutting equations can be analytically continued as a whole. We make explicit calculations in the cases of the bubble and triangle diagrams and address the generality of our approach. We also show that the same higher-derivative models violate unitarity if they are formulated directly in Minkowski spacetime.

  3. ‘Dolls in Agony’: Vernon Lee in Southern Spain

    OpenAIRE

    Barrera-Medrano, Leire

    2016-01-01

    Lorsque Vernon Lee se rendit dans le sud de l’Espagne en 1889, elle trouva que les pratiques catholiques qui y étaient exercées étaient extrêmement déroutantes. La décoration excessive des églises et le penchant local pour des représentations sanglantes du Christ en croix étaient, d’après elle, « obscènes » et « excessives ». En particulier, la représentation des Madones espagnoles, constamment figurées éplorées, lui répugnait. Ce sentiment de rejet envers ce pays catholique et plus particuli...

  4. Proses Individuasi Carl Gustav Jung pada Tokoh Erika Kohut dalam Novel Sang Guru Piano Karya Elfriede Jelinek

    Directory of Open Access Journals (Sweden)

    M. Oktavia Vidiyanti

    2007-12-01

    Full Text Available A personality structure that appears in Erika is similar to one of an important part of Carl Gustav Jung psychology. Jung states that personality is a psiko that covers consciousness and unconsciousness. This psiko will develop to be a stable unity. If every system develops in every individual absolutely, so a health and integrated personality will be achieved. That process in Jung is known as a self­ individualized process. The aim of individualism is a self­achievement. Individual is not only as a psiko centre but also as a representation of the whole individual that unites consciousness and unconsciousness. It is like the character "Erika Kohut" in the novel "Sang Guru Piano".

  5. A multi-developing-country comparison of the lee-carter model for ...

    African Journals Online (AJOL)

    This study evaluate the Lee-Carter model for projecting age and gender specific mortality rates and life expectancy at births in four developing countries namely Malaysia, Indonesia, Thailand and Singapore. Although the Lee-Carter model has been successfully applied in many developed countries, little information is ...

  6. Tim Berners-Lee at the RSIS conference from 8-9 December 2003.

    CERN Multimedia

    Patrice Loiez

    2003-01-01

    Tim Berners-Lee participated in the Role of Science in the Information Society conference held at CERN from 8-9 December 2003. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  7. Grain-size sorting in grainflows at the lee side of deltas

    NARCIS (Netherlands)

    Kleinhans, M.G.

    2005-01-01

    The sorting of sediment mixtures at the lee slope of deltas (at the angle of repose) is studied with experiments in a narrow, deep flume with subaqueous Gilbert-type deltas using varied flow conditions and different sediment mixtures. Sediment deposition and sorting on the lee slope of the delta

  8. James Lee Byars 1/2 an autobiography, sourcebook

    CERN Document Server

    Byars, James Lee; Eleey, Peter

    2014-01-01

    "I see my autobiography as an arbitrary segment of so many pages of time, of things that I have paid attention to at this point in my life," wrote James Lee Byars (1932-1997) in 1969. He was then 37, about half the average male lifespan at the time, and accordingly thought it appropriate to write his "1/2 autobiography." Byars' art ranged from highly refined objects to extremely minimal performance and events, and books, ephemera and correspondence that he distributed widely among friends and colleagues. Today, more than 15 years after his death, assessments of his art must negotiate Byars' performance of his charismatic self in his life and art. For his first major posthumous survey in the US, exhibition curators Magalí Arriola and Peter Eleey decided to produce a catalogue in two "halves," playing on his "1/2 autobiography": a catalogue of the exhibition itself, including new scholarship, and a sourcebook of primary documents. 1/2 an Autobiography, Sourcebook constitutes the latter volume--a reference guid...

  9. Carence en fer, anémie et anémie ferriprive chez les donneurs de sang à Kinshasa, République Démocratique du Congo

    Science.gov (United States)

    Nzengu-Lukusa, Franck; Yuma-Ramazani, Sylvain; Sokolua-Mvika, Eddy; Dilu-Keti, Angèle; Malenga-Nkanga, Blanchard; Shuli, Jean Baptiste; Nzongola-Nkasu, Donatien Kayembe; Mbayo-Kalumbu, Ferdinand; Ahuka-Mundeke, Steve

    2016-01-01

    Introduction En République Démocratique du Congo (RDC), plus d'un million de don de sang ont été réalisés entre 2007 et 2011. Cependant, aucun bilan portant sur la carence en fer et l'anémie ferriprive, conséquence d'un don de sang chez les donneurs de sang (DS), n'est disponible dans ce pays. L'objectif de cette étude était d'estimer la prévalence de la carence en fer, de l'anémie et de l'anémie ferriprive chezles DS au Centre National de Transfusion Sanguine (CNTS) à Kinshasa en RDC. Méthodes Entre Décembre 2012 et Août 2013, une étude transversale a été menée au CNTS où des DS éligibles au don de sang ont été inclus. Les informations socio démographiques et des prélèvements sanguins ont été collectés de manière simultanée au don de sang. La ferritine sérique a été dosée pour évaluer la carence en fer en utilisant la technique ELISA. L'hémogramme a été réalisé en vue d’évaluer et mettre au point l'anémie. Résultats Au total 386 DS ont été inclus dans cette étude. La prévalence de la carence en fer et de l'anémie ferriprive étaient respectivement de 63,2% (244/386) et 25,9% (100/386) des DS. Une anémie a été trouvée chez 36.5% (141/386) au moment du don de sang. Conclusion La carence en fer, l'anémie et l'anémie ferriprive demeurent très fréquentes chez les DS à Kinshasa. Ces résultats suggèrent la révision des tests biologiques utilisés dans le recrutement des DS au CNTS. Par ailleurs le dosage de la ferritine s'impose en routine chez les DS rég PMID:27303590

  10. Estudo da associação entre o sistema histo-sangüíneo ABO e a malária por Plasmodium falciparum na Amazônia brasileira

    OpenAIRE

    Carvalho, Danila Blanco de [UNESP

    2008-01-01

    O sistema sangüíneo ABO (sABO) é o mais importante sistema na compatibilidade de grupos sangüíneos. Muitas pesquisas têm mostrado associações deste sistema com várias doenças infecciosas, inclusive a malária. Este estudo avaliou a associação entre os genótipos do sistema histo-sangüíneo ABO e a malária não grave causada pelo Plasmodium falciparum. A genotipagem dos grupos sangüíneos do sistema ABO foi feita de acordo com o protocolo de PCR/ RFLP, em amostras de indivíduos maláricos e não malá...

  11. TRANSFORMASI PEWAYANGAN DALAM TOKOH WISANGGENI SEBUAH ANALISIS INTERTEKSTUAL NOVEL WISANGGENI SANG BURONAN KARYA SENO GUMIRA ADJIDARMA DENGAN KOMIK LAHIRNYA BANGBANG WISANGGENI KARYA RA. KOSASIH

    Directory of Open Access Journals (Sweden)

    Mila Kurnia Sari

    2017-10-01

    Abstract This study aims to reveal the intertextuality relationship between the novel Wisanggeni Sang Buronan by Seno Gumira Adjidarma and Lahirnya Bangbang Wisanggeni by  of R.A. Kosasih in the context of Indonesiaan today. This type of research is qualitative approach using content analysis. Data collected by inventory events such as the similarities and differences of both text and see the transformation of the puppet in the text. The research results indicate first, Wisanggeni Sang Buronan  by Seno Gumira Adjidarma can be interpreted as a social critic. Seno Gumira Adjidarma signaled to readers that characters like  Wisanggeni indispensable in this country. Second, Wisanggeni, in the novel Wisanggeni Sang Buronan and  Comics Lahirnya Bangbang Wisanggeni by R.A Kosasih has a very strong character. And third, Seno Gumira Adjidarma presents the figure Wisanggeni in different forms such as  presented by RA. Kosasih in Lahirnya Bangbang Wisanggeni by  Seno Gumira Adjidarma want to re-introduce Wisanggeni as a knight in the puppet is also example in courage. Keywords: Transformation, Pupets, Novels, Comics, Intertektualitas.

  12. Test procedure for the Master-Lee and the modified Champion four inch hydraulic cutters

    International Nuclear Information System (INIS)

    Crystal, J.B.

    1995-01-01

    The Master-Lee and the modified Champion 4 Inch hydraulic cutters are being retested to gather and document information related to the following: determine if the Master-Lee cutters will cut the trunnions of an Aluminum fuel canister and a Stainless Steel fuel canister; determine if the Master-Lee cutters will cut 1 1/2 inch diameter fire hose; determine if the modified Champion 4 inch blade will cut sections of piping; and determine the effectiveness of the centering device for the Champion 4 Inch cutters. Determining the limitations of the hydraulic cutter will aid in the process of debris removal in the K-Basin. Based on a previous test, the cutters were returned to the manufacturer for modifications. The modifications to the Champion 4 Inch Cutter and further testing of the Master-Lee Cutter are the subjects of these feature tests

  13. 75 FR 11225 - Environmental Impact Statement; Lee and Collier Counties, Florida

    Science.gov (United States)

    2010-03-10

    ... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Environmental Impact Statement; Lee and Collier Counties, Florida AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of... INFORMATION CONTACT: Mr. George Hadley, Environmental Programs Coordinator, Federal Highway Administration...

  14. Näitleja Tommy Lee Jonesi meditatsioon režissööritoolis / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2007-01-01

    Vestern "Melquiades Estrada kolm matust" ("The Three Burials of Melquiades Estrada") : stsenarist Guillermo Arriaga : režissöör ja osatäitja Tommy Lee Jones : operaator Chris Menges : Ameerika Ühendriigid, 2005

  15. The Pitzer-Lee-Kesler-Teja (PLKT) Strategy and Its Implementation by Meta-Computing Software

    Czech Academy of Sciences Publication Activity Database

    Smith, W. R.; Lísal, Martin; Missen, R. W.

    2001-01-01

    Roč. 35, č. 1 (2001), s. 68-73 ISSN 0009-2479 Institutional research plan: CEZ:AV0Z4072921 Keywords : The Pitzer-Lee-Kesler-Teja (PLKT) strategy * implementation Subject RIV: CF - Physical ; Theoretical Chemistry

  16. Behind their eyes : identity in the work of Li-Young Lee and Suji Kwock Kim

    OpenAIRE

    Hand, Meadhbh

    2014-01-01

    The introduction to this study outlines the theoretical framework for comparing the work of Li-Young Lee and Suji Kwock Kim. Using Walter Mignolo's theories about "border thinking," which he outlined in Local Histories/Global Designs, alongside Anzaldua's Borderlands/La Frontera as a basis for approaching Kim's and Lee's work, I demonstrate how the poets may be considered as embodying the role of border thinkers. Marianne Hirsch's definition of "postmemory," is explored, and its relevance to ...

  17. Comparative genomics and stx phage characterization of LEE-negative Shiga toxin-producing Escherichia coli

    Directory of Open Access Journals (Sweden)

    Susan Renee Steyert

    2012-11-01

    Full Text Available Infection by Escherichia coli and Shigella species are among the leading causes of death due to diarrheal disease in the world. Shiga toxin producing Escherichia coli (STEC that do not encode the locus of enterocyte effacement (LEE-negative STEC often possess Shiga toxin gene variants and have been isolated from humans and a variety of animal sources. In this study, we compare the genomes of nine LEE-negative STEC harboring various stx alleles with four complete reference LEE-positive STEC isolates. Compared to a representative collection of prototype E. coli and Shigella isolates representing each of the pathotypes, the whole genome phylogeny demonstrated that these isolates are diverse. Whole genome comparative analysis of the 13 genomes revealed that in addition to the absence of the LEE pathogenicity island, phage encoded genes including non-LEE encoded effectors, were absent from all nine LEE-negative STEC genomes. Several plasmid-encoded virulence factors reportedly identified in LEE-negative STEC isolates were identified in only a subset of the nine LEE-negative isolates further confirming the diversity of this group. In combination with whole genome analysis, we characterized the lambdoid phages harboring the various stx alleles and determined their genomic insertion sites. Although the integrase gene sequence corresponded with genomic location, it was not correlated with stx variant, further highlighting the mosaic nature of these phages. The transcription of these phages in different genomic backgrounds was examined. Expression of the Shiga toxin genes, stx1 and/or stx2, as well as the Q genes, were examined with quantitative reverse transcriptase polymerase chain reaction (qRT-PCR assays. A wide range of basal and induced toxin induction was observed. Overall, this is a first significant foray into the genome space of this unexplored group of emerging and divergent pathogens.

  18. Kodu soo serval / Helju Koger

    Index Scriptorium Estoniae

    Koger, Helju, 1943-

    2008-01-01

    Projekteerimisbüroo Resand juhataja Andres Neeme kodu Põlva äärelinnas Ora jõe kaldal. Betoonvaiadele püstitatud elamu projekt valmis büroos Resand. Erilise "kivijõega" koduaia kujundas Andrese ema Aino Neeme. 9 värv. vaadet

  19. Characterization and Comparison of Wine Lees by Liquid Chromatography-Mass Spectrometry in High-Resolution Mode.

    Science.gov (United States)

    Delgado de la Torre, M P; Priego-Capote, F; Luque de Castro, M D

    2015-02-04

    Wine lees from 11 different wineries pertaining to two denominations of origin in Spain (La Rioja and Ribera del Duero) have been characterized in this research by LC-MS/MS in high-resolution mode. For this purpose, the wine lees were separated into the liquid phase (imbibed wine from lees) and the solid residue, which was dried and subjected to solid-liquid extraction assisted by microwaves (dried lees). Both fractions were separately analyzed and the fractions from the 11 wineries compared to find similarity in their patterns. The statistical analysis enabled both differences and common aspects in the composition of imbibed wine from lees and dried lees from all wineries to be found. MS/MS tentative identification of representative compounds in each fraction revealed the varied composition of wine lees with special emphasis on flavonoids such as quercetin, myricetin, and malvidin 3-galactoside, identified in extracts of dried lees, or other compounds such as kaempferol 3-(2',3'-diacetylrhamnoside)-7″-rhamnoside, aminocaproic acid, and citric acid, exclusively identified in imbibed wine from lees. The adsorbent capacity of the solid residue justified the high concentration of phenolic compounds in the extracts from solid lees. The differences found in the composition of the two phases support the separated exploitation of them.

  20. Cardioplegia sangüínea contínua normotérmica Normotermic continuous blood cardioplegy

    Directory of Open Access Journals (Sweden)

    Domingo M Braile

    1989-08-01

    Full Text Available Os autores discutem o emprego da cardioplegia, bem como sua composição. A parada imediata dos batimentos pode ser conseguida com soluções cardioplégicas cristalóides ou sangüíneas, oxigenadas ou não. O agente que leva o coração à parada pode ser potássio, magnésio, procaína ou, mesmo, quelantes e bloqueadores de cálcio associados entre si ou não, contando com a edição da hipotermia ou não. Deve-se ficar atento para a falsa sensação de proteção a que a baixa temperatura possa nos induzir, uma vez que o frio, por si só, não é suficiente para manter o miocárdio viável por longos períodos. Substratos, como glicose e oxigênio, devem ser fornecidos durante o período de clampeamento aórtico, para garantir algum metabolismo aeróbio, nesse período. A adição de outros substratos, como glutamato, aspartato e lactato, assim como ATP ou creatina fosfato, precursores de intermediários do ciclo de Krebs, podem melhorar muito a proteção miocárdica. A infusão de cardioplegia sangüínea normotérmica de forma contínua mantém as necessidades metabólicas básicas para a sobrevivência das células. A membrana celular, com todas as suas funções estruturais e secretoras, é o ponto mais sensível à injúria isquêmica. Os removedores de radicais livres (scavengers são protetores indiretos da membrana celular. A cardioplegia retrógrada permite melhorar a distribuição das soluções na árvore coronariana, sendo muito útil nas reoperações. Ela deve fazer parte da tática cirúrgica, sem esquecermos suas limitações. O momento da reperfusão é o mais importante da proteção miocárdica; é nesse período que ocorre a liberação de radicais livres. O uso de removedores (scavengers pode melhorar as condições e o resultado da reperfusão. A cardioplegia sangüínea oxigenada e normotérmica enriquecida com substratos, antes usada em casos extremamente graves, por disfunção muscular em isquemia mioc

  1. Lee-Yang zeros and large-deviation statistics of a molecular zipper

    Science.gov (United States)

    Deger, Aydin; Brandner, Kay; Flindt, Christian

    2018-01-01

    The complex zeros of partition functions were originally investigated by Lee and Yang to explain the behavior of condensing gases. Since then, Lee-Yang zeros have become a powerful tool to describe phase transitions in interacting systems. Today, Lee-Yang zeros are no longer just a theoretical concept; they have been determined in recent experiments. In one approach, the Lee-Yang zeros are extracted from the high cumulants of thermodynamic observables at finite size. Here we employ this method to investigate a phase transition in a molecular zipper. From the energy fluctuations in small zippers, we can predict the temperature at which a phase transition occurs in the thermodynamic limit. Even when the system does not undergo a sharp transition, the Lee-Yang zeros carry important information about the large-deviation statistics and its symmetry properties. Our work suggests an interesting duality between fluctuations in small systems and their phase behavior in the thermodynamic limit. These predictions may be tested in future experiments.

  2. Utilization of a factorial design to study the composting of hydrolyzed grape marc and vinification lees.

    Science.gov (United States)

    Paradelo, Remigio; Moldes, Ana B; Barral, María T

    2010-03-10

    Hydrolyzed grape marc (HGM) is the solid residue generated after the acid hydrolysis of grape marc to obtain hemicellulosic sugars for biotechnological purposes. In this work, HGM containing cellulose and lignin was composted together with vinification lees to obtain plant substrates on a laboratory scale. The effects of temperature (in the range of 20-50 degrees C), concentration of vinification lees (5-100 g/100 g of hydrolyzed grape marc), and concentration of CaCO(3) on the final properties of the composted HGM were studied by means of an experimental plan with factorial structure. The interrelationship between dependent and operational variables was established by models including linear, interaction, and quadratic terms. The most influential variable on the C/N ratio and P, K and Mg contents of composted substrates was the vinification lees concentration followed by the temperature, whereas on Na content and electrical conductivity the most influential variable was the temperature followed by the vinification lees concentration. The results of the incubation experiments indicated that optimal conditions for obtaining plant substrates can be achieved by composting 1:1 mixtures of hydrolyzed grape marc and vinification lees, in the presence of 5 g of CaCO(3)/100 g of HGM. During composting the pH of the mixtures increased from 5.1-6.7 to 7.1-8.1, salinity and water-soluble carbon were reduced in most cases, and the initial phytotoxicity disappeared in all of the mixtures tested.

  3. Practicing psychology in the art gallery: Vernon Lee's aesthetics of empathy.

    Science.gov (United States)

    Lanzoni, Susan

    2009-01-01

    Late nineteenth-century psychologists and aestheticians were fascinated by the study of psychological and physiological aspects of aesthetic response, and the British intellectual and aesthete Vernon Lee was a major participant in this venture. Working outside the academy, Lee conducted informal experiments with Clementina Anstruther-Thomson, recording changes in respiration, balance, emotion, and body movements in response to aesthetic form. In fashioning her aesthetics of empathy, she mined a wealth of psychological theories of the period including motor theories of mind, physiological theories of emotion, evolutionary models of the usefulness of art, and, most prominently, the empathic projection of feeling and movement into form. Lee distributed questionnaires, contributed to scientific journals, carried out her own introspective studies, and debated aesthetics with leading psychologists. This paper critiques the prevailing view of Lee's aesthetics as a displaced sign of her gender or sexuality, and questions her status as simply an amateur in the field of psychology. Instead, I argue that Lee's empirically based empathy theory of art was a significant contribution to debates on psychological aesthetics at the outset of the twentieth century, offering a synthesis of Lipps's mentalistic Einfühlung and sensation-based imitation theories of aesthetic response.

  4. Expression Regulation of Polycistronic lee3 Genes of Enterohaemorrhagic Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Wei-Sheng W Sun

    Full Text Available Enterohaemorrhagic Escherichia coli O157:H7 (EHEC carries a pathogenic island LEE that is consisted mainly of five polycistronic operons. In the lee3 operon, mpc is the first gene and has been reported to down regulate the type-3 secretion system of EHEC when its gene product is over-expressed. Furthermore, mpc has been suggested to have a regulation function via translation but the mechanism remains unclear. To clarify this hypothesis, we dissected the polycistron and examined the translated products. We conclude that translation of mpc detrimentally governs the translation of the second gene, escV, which in turn affects the translation of the third gene, escN. Then sequentially, escN affects the expression of the downstream genes. Furthermore, we located a critical cis element within the mpc open-reading frame that plays a negative role in the translation-dependent regulation of lee3. Using qRT-PCR, we found that the amount of mpc RNA transcript present in EHEC was relatively limited when compared to any other genes within lee3. Taken together, when the transcription of LEE is activated, expression of mpc is tightly controlled by a restriction of the RNA transcript of mpc, translation of which is then critical for the efficient production of the operon's downstream gene products.

  5. [Lee Jungsook, a Korean independence activist and a nurse during the Japanese colonial period].

    Science.gov (United States)

    Kim, Sook Young

    2015-04-01

    This article examines the life of Lee Jungsook, a Korean nurse, as a independence activist during the Japanese colonial period. Lee Jungsook(1896-1950) was born in Bukchung in Hamnam province. She studied at Chungshin girl's high school and worked at Severance hospital. The characteristics and culture of her educational background and work place were very important factors which influenced greatly the life of Lee Jungsook. She learned independent spirit and nationalism from Chungshin girls' high school and worked as nurse at the Severance hospital which were full of intense aspiration for Korea's independence. Many of doctors, professors and medical students were participated in the 3.1 Independence Movement. Lee Jungsook was a founding member of Hyulsungdan who tried to help the independence activists in prison and their families and worked as a main member of Korean Women's Association for Korean Independece and Kyungsung branch of the Korean Red Cross. She was sent to jail by the Japanese government for her independence activism. After being released after serving two years confinement, she worked for the Union for Women's Liberation as a founding member. Lee Joungsook was a great independence activist who had a nursing care spirit as a nurse.

  6. Duke Power's William Lee says INPO's purpose is solving industry problems, not educating the public

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    Former Institute of Nuclear Power Operations (INPO) head, William Lee thinks that nuclear critics could misuse institute reports on investigations of nuclear plant construction and operation. If so, that would outweigh any public relations benefits of using the reports to inform and educate the public. Lee thinks the best way to gain public confidence is for the industry to perform well. The four-year-old institute was originally formed to improve operations, but recent problems with unfinished plants led to a system of construction audits. By offering guidance to companies building nuclear plants, INPO is meeting competition from utilities such as Duke Power, which is now marketing its expertise in designing and building plants. Lee emphasizes the importance of asking the right questions that will lead to quality control

  7. Practical Improvements to the Lee-More Conductivity Near the Metal-Insulator Transition

    International Nuclear Information System (INIS)

    Desjarlais, Michael P.

    2000-01-01

    The wide-range conductivity model of Lee and More is modified to allow better agreement with recent experimental data and theories for dense plasmas in the metal-insulator transition regime. Modifications primarily include a new ionization equilibrium model, consisting of a smooth blend between single ionization Saha (with a pressure ionization correction) and the generic Thomas-Fermi ionization equilibrium, a more accurate treatment of electron-neutral collisions using a polarization potential, and an empirical modification to the minimum allowed collision time. These simple modifications to the Lee-More algorithm permit a more accurate modeling of the physics near the metal-insulator transition, while preserving the generic Lee-More results elsewhere

  8. Practical improvements to the Lee-More conductivity near the metal-insulator transition

    International Nuclear Information System (INIS)

    Desjarlais, M.P.

    2001-01-01

    The wide-range conductivity model of Lee and More is modified to allow better agreement with recent experimental data and theories for dense plasmas in the metal-insulator transition regime. Modifications primarily include a new ionization equilibrium model, consisting of a smooth blend between single ionization Saha (with a pressure ionization correction) and the generic Thomas-Fermi ionization equilibrium, a more accurate treatment of electron-neutral collisions using a polarization potential, and an empirical modification to the minimum allowed collision time. These simple modifications to the Lee-More algorithm permit a more accurate modeling of the physics near the metal-insulator transition, while preserving the generic Lee-More results elsewhere. (orig.)

  9. Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli

    Directory of Open Access Journals (Sweden)

    Kaparakis Maria

    2009-02-01

    Full Text Available Abstract Background Enteropathogenic Escherichia coli (EPEC is an attaching and effacing (A/E pathogen that possesses a type III secretion system (T3SS encoded within the locus of enterocyte effacement (LEE. The LEE is essential for A/E lesion formation and directs the secretion and translocation of multiple LEE-encoded and non-LEE encoded effector proteins into the cytosol of infected cells. In this study we used proteomics to compare proteins exported to the culture supernatant by wild type EPEC E2348/69, a ΔespADB mutant and a ΔescF T3SS mutant. Results We observed that flagellin was consistently and strongly present in the secretome of wild type EPEC and the ΔespADB mutant but present only weakly in the secretome of the ΔescF mutant. Given the ancestral relationship between the flagella export apparatus and virulence associated T3SSs, we investigated whether FliC could utilise the LEE-encoded T3SS for export. In the absence of a functional flagella export apparatus, we showed that FliC could be secreted by the LEE-encoded T3SS and stimulate (Toll-like receptor 5 TLR5 signalling but could not confer motility. Conclusion Since the secretion of FliC during A/E lesion formation would presumably be disadvantageous for the pathogen, we propose that virulence associated T3SSs and flagella T3SSs have evolved through a system of chaperones and complex regulatory pathways to be functional at different times to ensure that FliC secretion does not occur during T3SS effector translocation.

  10. Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli.

    Science.gov (United States)

    Badea, Luminita; Beatson, Scott A; Kaparakis, Maria; Ferrero, Richard L; Hartland, Elizabeth L

    2009-02-06

    Enteropathogenic Escherichia coli (EPEC) is an attaching and effacing (A/E) pathogen that possesses a type III secretion system (T3SS) encoded within the locus of enterocyte effacement (LEE). The LEE is essential for A/E lesion formation and directs the secretion and translocation of multiple LEE-encoded and non-LEE encoded effector proteins into the cytosol of infected cells. In this study we used proteomics to compare proteins exported to the culture supernatant by wild type EPEC E2348/69, a DeltaespADB mutant and a DeltaescF T3SS mutant. We observed that flagellin was consistently and strongly present in the secretome of wild type EPEC and the DeltaespADB mutant but present only weakly in the secretome of the DeltaescF mutant. Given the ancestral relationship between the flagella export apparatus and virulence associated T3SSs, we investigated whether FliC could utilise the LEE-encoded T3SS for export. In the absence of a functional flagella export apparatus, we showed that FliC could be secreted by the LEE-encoded T3SS and stimulate (Toll-like receptor 5) TLR5 signalling but could not confer motility. Since the secretion of FliC during A/E lesion formation would presumably be disadvantageous for the pathogen, we propose that virulence associated T3SSs and flagella T3SSs have evolved through a system of chaperones and complex regulatory pathways to be functional at different times to ensure that FliC secretion does not occur during T3SS effector translocation.

  11. Synchronization and anti-synchronization coexist in Chen-Lee chaotic systems

    International Nuclear Information System (INIS)

    Chen, J.-H.; Chen, H.-K.; Lin, Y.-K.

    2009-01-01

    This study demonstrates that synchronization and anti-synchronization can coexist in Chen-Lee chaotic systems by direct linear coupling. Based on Lyapunov's direct method, a linear controller was designed to assure that two different types of synchronization can simultaneously be achieved. Further, the hybrid projective synchronization of Chen-Lee chaotic systems was studied using a nonlinear control scheme. The nonlinear controller was designed according to the Lyapunov stability theory to guarantee the hybrid projective synchronization, including synchronization, anti-synchronization, and projective synchronization. Finally, numerical examples are presented in order to illustrate the proposed synchronization approach.

  12. Deterministic and stochastic trends in the Lee-Carter mortality model

    DEFF Research Database (Denmark)

    Callot, Laurent; Haldrup, Niels; Kallestrup-Lamb, Malene

    2015-01-01

    The Lee and Carter (1992) model assumes that the deterministic and stochastic time series dynamics load with identical weights when describing the development of age-specific mortality rates. Effectively this means that the main characteristics of the model simplify to a random walk model with age...... mortality data. We find empirical evidence that this feature of the Lee–Carter model overly restricts the system dynamics and we suggest to separate the deterministic and stochastic time series components at the benefit of improved fit and forecasting performance. In fact, we find that the classical Lee...

  13. Deterministic and stochastic trends in the Lee-Carter mortality model

    DEFF Research Database (Denmark)

    Callot, Laurent; Haldrup, Niels; Kallestrup-Lamb, Malene

    The Lee and Carter (1992) model assumes that the deterministic and stochastic time series dynamics loads with identical weights when describing the development of age specific mortality rates. Effectively this means that the main characteristics of the model simplifies to a random walk model...... that characterizes mortality data. We find empirical evidence that this feature of the Lee-Carter model overly restricts the system dynamics and we suggest to separate the deterministic and stochastic time series components at the benefit of improved fit and forecasting performance. In fact, we find...

  14. Sang i Demensplejen

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner

    2004-01-01

    For mange svært demensramte er det umuligt at deltage i en aktivitet med andre personer. De har svært ved at forstå, hvad der foregår omkring dem, og bliver urolige og "forstyrrende". Eller de falder i søvn. Artiklen giver et bud på, hvordan den gruppe af demensramte, som ofte beskrives som uroli...

  15. Jõulukuine plaadisadu / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2005-01-01

    Lühidalt eesti heliplaatidest: "Eesti hääled", "Hendrik Sal-Saller & Estonian Dream Big Band", "Ain Agan ja Tallinna Kammerorkester", "The Book's Burning", "Mu süda ärka üles", "Inimene õpib...", "You Stepped Out of a Dream", "Andke tagasi maa", "Jesli ljubish, naidi..."

  16. Una ciudad de los vascones en el yacimiento de Campo Real/Fillera (Sos del Rey Católico-Sangüesa

    Directory of Open Access Journals (Sweden)

    Andreu Pintado, Javier

    2008-12-01

    Full Text Available The following paper deals with the detailed and preliminary study of the archaeological site of Campo Real/Fillera (Sos del Rey Católico/Sangüesa, between today Zaragoza and Navarra provinces specially focusing in its Roman period. The paper exposes a review of the archeological and epigraphical material from the site, proposes an urban condition for it and raises some hypothesis on its identification with one of the cities that ancient sources tribued to Vascones.El presente trabajo aborda el estudio detallado y preliminar del yacimiento arqueológico de Campo Real/Fillera (Sos del Rey Católico/Sangüesa, en el límite entre las actuales provincias de Zaragoza y Navarra con especial atención a su etapa romana. Se procede a la revisión del material arqueológico y epigráfico procedente del lugar, se defiende la condición de enclave urbano del yacimiento y se plantea una hipótesis respecto de su identificación con las ciudades que las fuentes antiguas atribuyen a los Vascones.

  17. What the Butler Saw: Lee Daniels's Studies in Biography and History

    Science.gov (United States)

    Beck, Bernard

    2014-01-01

    The movie "Lee Daniels' The Butler" is an example of a work that is meant not only to entertain but to convey an important attitude and offer important viewpoints. The movie deals with a deep issue in the history of movies and the history of the country: racial inequality. Three issues are discussed in this article: (a) African…

  18. Optimization Evaluation: Lee Chemical Superfund Site, City Of Liberty, Clay County, Missouri

    Science.gov (United States)

    The Lee Chemical Superfund Site (site) is located along Missouri Highway 210 in Liberty, Missouri, approximately 15 miles east of Kansas City, Missouri. Currently, the site is a vacant lot of approximately2.5 acres in a flat alluvial plain.

  19. Forecasting selected specific age mortality rate of Malaysia by using Lee-Carter model

    Science.gov (United States)

    Shukri Kamaruddin, Halim; Ismail, Noriszura

    2018-03-01

    Observing mortality pattern and trend is an important subject for any country to maintain a good social-economy in the next projection years. The declining in mortality trend gives a good impression of what a government has done towards macro citizen in one nation. Selecting a particular mortality model can be a tricky based on the approached method adapting. Lee-Carter model is adapted because of its simplicity and reliability of the outcome results with approach of regression. Implementation of Lee-Carter in finding a fitted model and hence its projection has been used worldwide in most of mortality research in developed countries. This paper studies the mortality pattern of Malaysia in the past by using original model of Lee-Carter (1992) and hence its cross-sectional observation for a single age. The data is indexed by age of death and year of death from 1984 to 2012, in which are supplied by Department of Statistics Malaysia. The results are modelled by using RStudio and the keen analysis will focus on the trend and projection of mortality rate and age specific mortality rate in the future. This paper can be extended to different variants extensions of Lee-Carter or any stochastic mortality tool by using Malaysia mortality experience as a centre of the main issue.

  20. INCA Modelling of the Lee System: strategies for the reduction of nitrogen loads

    Science.gov (United States)

    Flynn, N. J.; Paddison, T.; Whitehead, P. G.

    The Integrated Nitrogen Catchment model (INCA) was applied successfully to simulate nitrogen concentrations in the River Lee, a northern tributary of the River Thames for 1995-1999. Leaching from urban and agricultural areas was found to control nitrogen dynamics in reaches unaffected by effluent discharges and abstractions; the occurrence of minimal flows resulted in an upward trend in nitrate concentration. Sewage treatment works (STW) discharging into the River Lee raised nitrate concentrations substantially, a problem which was compounded by abstractions in the Lower Lee. The average concentration of nitrate (NO3) for the simulation period 1995-96 was 7.87 mg N l-1. Ammonium (NH4) concentrations were simulated less successfully. However, concentrations of ammonium rarely rose to levels which would be of environmental concern. Scenarios were run through INCA to assess strategies for the reduction of nitrate concentrations in the catchment. The conversion of arable land to ungrazed vegetation or to woodland would reduce nitrate concentrations substantially, whilst inclusion of riparian buffer strips would be unsuccessful in reducing nitrate loading. A 50% reduction in nitrate loading from Luton STW would result in a fall of up to 5 mg N l-1 in the reach directly affected (concentrations fell from maxima of 13 to 8 mg N l-1 , nearly a 40 % reduction), whilst a 20% reduction in abstractions would reduce maximum peaks in concentration in the lower Lee by up to 4 mg l-1 (from 17 to 13 mg N l-1, nearly a 25 % reduction),.

  1. Servicing the first web server - Tim Berners-Lee's NeXT

    CERN Multimedia

    unknown, Association aBCM

    2009-01-01

    In August 2009 a team from the Association aBCM in Lausanne came to CERN to give the world's first web server a health check under the watchful eye of web pioneer Robert Cailliau. They took an image of the hard drive at this time, copies of which were given to Robert Cailliau and Tim Berners-Lee.

  2. Charcot, Mitchell and Lees: neurology free thinkers and their experiences of psychoactive drugs

    Directory of Open Access Journals (Sweden)

    Hélio A. G. Teive

    Full Text Available ABSTRACT Three world-famous neurologists, Charcot and Mitchell, in the 19th century, and Lees, in this century, all of whom had great scientific curiosity, experimented with the psychoactive drugs hashish, mescal and yagé, respectively, in an attempt to increase their knowledge of neurological diseases and how the brain works.

  3. Yang-Lee edge singularity on a class of tree-like lattices

    Energy Technology Data Exchange (ETDEWEB)

    Knezevic, Milan; Elezovic-Hadzic, Suncica [Faculty of Physics, University of Belgrade, Belgrade (Yugoslavia)

    1997-03-21

    The density of zeros of the partition function of the Ising model on a class of tree-like lattices is studied. An exact closed-form expression for the pertinent critical exponents is derived by using a couple of recursion relations which have a singular behaviour near the Yang-Lee edge. (author)

  4. Fighting with Reality: Considering Mark Johnson's Pragmatic Realism through Bruce Lee's Jeet Kune Do Method

    Science.gov (United States)

    Miller, Alexander David

    2015-01-01

    This dissertation considers the supportive and complementary relation between Mark Johnson's embodied realism and Bruce Lee's Jeet Kune Do as a philosophical practice. In exploring this relationship, the emphasis on one's embodiment condition and its relationship with metaphor and self-expression are the primary focus. First, this work involves…

  5. Lee-side flow structures of very low aspect ratio cruciform wing–body configurations

    CSIR Research Space (South Africa)

    Tuling, S

    2013-12-01

    Full Text Available OF SPACECRAFT AND ROCKETS Vol. 50, No. 6, November–December 2013 Lee-Side Flow Structures of Very Low Aspect Ratio Cruciform Wing–Body Configurations S. Tuling∗ Council for Scientific and Industrial Research, Pretoria 0001, South Africa L. Dala...

  6. Thomas George Lee - Implantation and early development of North American rodents

    DEFF Research Database (Denmark)

    Carter, Anthony Michael

    2011-01-01

    A century ago Thomas G. Lee amassed an unparalleled collection of developmental series of North American rodents such as the thirteen-lined ground squirrel, the Plains pocket gopher and Merriam's kangaroo rat. He was the first to describe the initial attachment of the squirrel blastocyst...

  7. Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157:H7.

    Science.gov (United States)

    Roe, Andrew J; Naylor, Stuart W; Spears, Kevin J; Yull, Helen M; Dransfield, Tracy A; Oxford, Matthew; McKendrick, Iain J; Porter, Megan; Woodward, Martin J; Smith, David G E; Gally, David L

    2004-10-01

    Escherichia coli O157:H7 is a zoonotic pathogen that can express a type III secretion system (TTSS) considered important for colonization and persistence in ruminants. E. coli O157:H7 strains have been shown to vary markedly in levels of protein secreted using the TTSS and this study has confirmed that a high secretion phenotype is more prevalent among isolates associated with human disease than isolates shed by healthy cattle. The variation in secretion levels is a consequence of heterogeneous expression, being dependent on the proportion of bacteria in a population that are actively engaged in protein secretion. This was demonstrated by indirect immunofluorescence and eGFP fusions that examined the expression of locus of enterocyte effacement (LEE)-encoded factors in individual bacteria. In liquid media, the expression of EspA, tir::egfp, intimin, but not map::egfp were co-ordinated in a subpopulation of bacteria. In contrast to E. coli O157:H7, expression of tir::egfp in EPEC E2348/69 was equivalent in all bacteria although the same fusion exhibited variable expression when transformed into an E. coli O157:H7 background. An E. coli O157:H7 strain deleted for the LEE demonstrated weak but variable expression of tir::egfp indicating that the elements controlling the heterogeneous expression lie outside the LEE. The research also demonstrated the rapid induction of tir::egfp and map::egfp on contact with bovine epithelial cells. This control in E. coli O157:H7 may be required to limit exposure of key surface antigens, EspA, Tir and intimin during colonization of cattle but allow their rapid production on contact with bovine gastrointestinal epithelium at the terminal rectum.

  8. The medical theory of Lee Je-ma and its character

    Directory of Open Access Journals (Sweden)

    LEE Kyung-Lock

    2005-12-01

    Full Text Available Lee Je-ma(李濟馬, 1837-1900 was a prominent scholar as well as an Korean physician He classified every people into four distinctive types: greater yang[tai yang] person, lesser yin[shao yin] person greater yin[tai yin] person, lesser yin[shao yin] person. This theory would dictate proper treatment for each type in accordance with individual differences of physical and temperament features Using these four types he created The Medical Science of Four Types(四象體質論.This article is intended to look into the connection between Lee Je-Ma's 'The Medical Science of Four Types' and 'The Modern' with organizing his ideas about the human body and the human being. Through The Modern, the theory of human being(人間觀 underwent a complete change. Human being in The Premodern, which was determined by sex, age and social status has been changed to the individual human being, which is featured by equality. Lee Je-Ma's medical theory of The Medical Science of Four Types would be analyzed as follow. His concept of human body(人體論 is oriented toward observable objectivity. But on the other hand, it still remains transcendent status of medical science, which is subordinated by philosophy According to Lee Je-Ma's theory of human being human is an equal individual in a modern way of thinking not as a part of hierarchical group. But on the other hand, it still remains incomplete from getting rid of morality aspect that includes virtue and vice in the concept of human body.The common factors in Lee Je-Ma's ideas about the human body and the human being is 'Dualism of mind and body(心身二元論' that means all kinds of status and results depends on each individual. As is stated above, Lee Je-Ma's medical theory has many aspects of The Modern and it proves that Korean traditional medicine could be modernized by itself.

  9. Water quality and ecology of the River Lee: mass balance and a review of temporal and spatial data

    Directory of Open Access Journals (Sweden)

    D. L. Snook

    2004-01-01

    Full Text Available A regional overview of the water quality and ecology of the River Lee catchment is presented. Specifically, data describing the chemical, microbiological and macrobiological water quality and fisheries communities have been analysed, based on a division into river, sewage treatment works, fish-farm, lake and industrial samples. Nutrient enrichment and the highest concentrations of metals and micro-organics were found in the urbanised, lower reaches of the Lee and in the Lee Navigation. Average annual concentrations of metals were generally within environmental quality standards although, on many occasions, concentrations of cadmium, copper, lead, mercury and zinc were in excess of the standards. Various organic substances (used as herbicides, fungicides, insecticides, chlorination by-products and industrial solvents were widely detected in the Lee system. Concentrations of ten micro-organic substances were observed in excess of their environmental quality standards, though not in terms of annual averages. Sewage treatment works were the principal point source input of nutrients, metals and micro-organic determinands to the catchment. Diffuse nitrogen sources contributed approximately 60% and 27% of the in-stream load in the upper and lower Lee respectively, whereas approximately 60% and 20% of the in-stream phosphorus load was derived from diffuse sources in the upper and lower Lee. For metals, the most significant source was the urban runoff from North London. In reaches less affected by effluent discharges, diffuse runoff from urban and agricultural areas dominated trends. High microbiological content, observed in the River Lee particularly in urbanised reaches, was far in excess of the EC Bathing Water Directive standards. Water quality issues and degraded habitat in the lower reaches of the Lee has led to impoverished aquatic fauna but, within the mid-catchment reaches and upper agricultural tributaries, less nutrient enrichment and channel

  10. Níveis de plasma sangüíneo em pó em dietas para leitões desmamados aos 21 dias de idade

    OpenAIRE

    Barbosa,Fellipe Freitas; Ferreira,Aloízio Soares; Gattás,Gustavo; Silva,Francisco Carlos de Oliveira; Donzele,Juarez Lopes; Brustolini,Paulo César; Lopes,Darci Clementino

    2007-01-01

    Objetivando-se avaliar níveis de inclusão de plasma sangüíneo em pó nas dietas para leitões desmamados aos 21 dias de idade, foram utilizados 112 animais com peso inicial de 5,90 ± 0,40 kg distribuídos em delineamento experimental de blocos ao acaso com quatro tratamentos e sete repetições com quatro animais por unidade experimental, em três períodos subseqüentes: 21 aos 28 dias (período 1), 29 aos 35 dias (período 2) e 36 aos 42 dias (período 3). Os leitões foram mantidos no experimen...

  11. Parametric study of the fractional-order Chen-Lee system

    Energy Technology Data Exchange (ETDEWEB)

    Tam, L.M. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Tomas Pereira S.J., Taipa, Macau (China)], E-mail: fstlmt@umac.mo; Tou, W.M.S. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Tomas Pereira S.J., Taipa, Macau (China)

    2008-08-15

    The dynamics of fractional-order systems have attracted a great deal of attention in recent years. In this paper, the effects of parameter changes on the dynamics of the fractional-order Chen-Lee system were studied numerically. The parameter ranges used were relatively broad. The order used for the system was fixed at 2.7 (q{sub 1} = q{sub 2} = q{sub 3} = 0.9). The system displays rich dynamic behaviors, such as a fixed point, periodic motion (including period-3 motion), chaotic motion, and transient chaos. The chaotic motion identified was validated by the confirmation of a positive Lyapunov exponent. Period-doubling routes to chaos in the fractional-order Chen-Lee system were also found.

  12. Lee Wen: Lucid Dreams In the Reverie of the Real

    OpenAIRE

    Mokhtari, Sylvie

    2012-01-01

    Cette monographie rétrospective réunit la somme des travaux, associant depuis vingt ans performances et installations, de l’artiste singapourien Lee Wen (né en 1957). Ambigu et très expressive, son activité est relatée de manière biographique sous la plume de Khairuddin Hori (« If you can’t think because you can’t chew, try a banana », pp.9-19). Textes de et sur Lee Wen, témoignages, documents et travaux viennent ensuite généreusement nourrir la publication. Des Anthropométries d’Yves Klein, ...

  13. The Brain Dead Patient Is Still Sentient: A Further Reply to Patrick Lee and Germain Grisez.

    Science.gov (United States)

    Austriaco, Nicanor Pier Giorgio

    2016-06-01

    Patrick Lee and Germain Grisez have argued that the total brain dead patient is still dead because the integrated entity that remains is not even an animal, not only because he is not sentient but also, and more importantly, because he has lost the radical capacity for sentience. In this essay, written from within and as a contribution to the Catholic philosophical tradition, I respond to Lee and Grisez's argument by proposing that the brain dead patient is still sentient because an animal with an intact but severed spinal cord can still perceive and respond to external stimuli. The brain dead patient is an unconscious sentient organism. © The Author 2016. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE Pathogenicity Island in Enteropathogenic Escherichia coli

    Directory of Open Access Journals (Sweden)

    Hervé Leh

    2017-08-01

    Full Text Available In enteropathogenic Escherichia coli (EPEC, the locus of enterocyte effacement (LEE encodes a type 3 secretion system (T3SS essential for pathogenesis. This pathogenicity island comprises five major operons (LEE1 to LEE5, with the LEE5 operon encoding T3SS effectors involved in the intimate adherence of bacteria to enterocytes. The first operon, LEE1, encodes Ler (LEE-encoded regulator, an H-NS (nucleoid structuring protein paralog that alleviates the LEE H-NS silencing. We observed that the LEE5 and LEE1 promoters present a bimodal expression pattern, depending on environmental stimuli. One key regulator of bimodal LEE1 and LEE5 expression is ler expression, which fluctuates in response to different growth conditions. Under conditions in vitro considered to be equivalent to nonoptimal conditions for virulence, the opposing regulatory effects of H-NS and Ler can lead to the emergence of two bacterial subpopulations. H-NS and Ler share nucleation binding sites in the LEE5 promoter region, but H-NS binding results in local DNA structural modifications distinct from those generated through Ler binding, at least in vitro. Thus, we show how two nucleoid-binding proteins can contribute to the epigenetic regulation of bacterial virulence and lead to opposing bacterial fates. This finding implicates for the first time bacterial-chromatin structural proteins in the bimodal regulation of gene expression.

  15. Siapakah Dia: Sang Penasihat Ajaib, Allah yang Perkasa, Bapa yang Kekal dan Raja Damai? Studi Terhadap Makna Teks Yesaya 8:23-9:6

    Directory of Open Access Journals (Sweden)

    Marde Christian Stenly Mawikere

    2015-06-01

    Full Text Available Panggilan dan pelayanan kenabian Yesaya berada dalam situasi genting seperti yang telah diungkapkan di atas.  Akan tetapi penekanan nubuat Yesaya adalah kepada eksistensi dan atribut Tuhan Yang Mahakudus yang dapat dipercaya dan diandalkan.  Bergantung kepada manusia sekuat atau sehebat apapun kekuasaannya hanya bersifat sementara dan cenderung membahayakan dalam waktu yang lama.  Sedangkan bergantung pada Allah justru membawa  damai sejahtera dan pemulihan.  Dalam situasi genting, sendiri hadir dan bertindak untuk membebaskan dan menyelamatkan bangsa Israel.  Tuhan jugalah yang merupakan “Sang Penasihat Ajaib, Allah Yang Perkasa, Bapa Yang Kekal, Raja Damai” yang dapat dipercaya dan diandalkan ketimbang raja-raja, kerajaan-kerajaan maupun orang-orang bijaksana.  Bangsa Israel sebagai pendengar nubuat Yesaya maupun pembaca mula-mula Kitab Yesaya telah mendengar hal tersebut, sekalipun mereka “tidak mengerti, tidak menanggapi, tidak mendengar, menutup mata dan tidak melihat” (Yesaya 6:9-10.           Bagi orang Kristen yang memercayai Tuhan Yesus Kristus sebagai Tuhan yang menjadi daging (Yohanes 1:14, disamping memiliki kekayaan yang melimpah dalam terang Perjanjian Baru untuk mengenal dan memahami pribadi dan karya Tuhan Yesus Kristus, juga terdapat Perjanjian Lama dengan kekayaan yang sama yakni sebagai kitab untuk menelusuri akar-akar inkarnasi Sang Juruselamat!  Karena itu, sebetulnya pemberitaan firman Tuhan dari Yesaya 8:23-9:6 tidak melulu hanya disampaikan pada “musim perayaan Natal”, namun menjadi pemberitaan sepanjang masa dalam situasi sukacita terlebih dalam situasi genting.  Karena Tuhan begitu mengasihi dan mempedulikan setiap situasi manusia dan ciptaan-Nya, bahkan seperti cinta orang muda; dengan “kasih yang cemburu”!

  16. Grape marc, wine lees and deposit of the must: How to manage oenological by-products?

    OpenAIRE

    Lempereur Valérie; Penavayre Sophie

    2014-01-01

    Winemaking produces solid (grape marc) and liquid (wine lees and deposit of the must) wastes named “oenological by-products”, which, according to European regulations, must be eliminated following the environmental regulatory requirement [1]. In France, these European regulations forced wine growers, until the 2013/2014 campaign, to deliver all by-products to wine distilleries. This French obligation is known as the “prestation vinique” [2, 3]. Following the Common Market Organisation wine re...

  17. LEE: Light‐Weight Energy‐Efficient encryption algorithm for sensor networks

    OpenAIRE

    Komninos, N.; Soroush, H.; Salajegheh, M.

    2007-01-01

    Data confidentiality in wireless sensor networks is mainly achieved by RC5 and Skipjack encryption algorithms. However, both algorithms have their weaknesses, for example RC5 supports variable-bit rotations, which are computationally expensive operations and Skipjack uses a key length of 80-bits, which is subject to brute force attack. In this paper we introduce a light-weight energy- fficient encryption-algorithm (LEE) for tiny embedded devices, such as sensor network nodes. We present exper...

  18. Nobelist TD LEE Scientist Cooperation Network and Scientist Innovation Ability Model

    OpenAIRE

    Fang, Jin-Qing; Liu, Qiang

    2013-01-01

    Nobelist TD Lee scientist cooperation network (TDLSCN) and their innovation ability are studied. It is found that the TDLSCN not only has the common topological properties both of scale-free and small-world for a general scientist cooperation networks, but also appears the creation multiple-peak phenomenon for number of published paper with year evolution, which become Nobelist TD Lee’s significant mark distinguished from other scientists. This new phenomenon has not been revealed in the scie...

  19. Becoming an International Scientist in South Korea: Ho Wang Lee's Research Activity about Epidemic Hemorrhagic Fever.

    Science.gov (United States)

    Shin, Miyoung

    2017-04-01

    In the 1960-70s, South Korea was still in the position of a science latecomer. Although the scientific research environment in South Korea at that time was insufficient, there was a scientist who achieved outcomes that could be recognized internationally while acting in South Korea. He was Ho Wang Lee(1928~ ) who found Hantann Virus that causes epidemic hemorrhagic fever for the first time in the world. It became a clue to identify causative viruses of hemorrhagic diseases that were scattered here and there throughout the world. In addition, these outcomes put Ho Wang Lee on the global center of research into epidemic hemorrhagic fever. This paper examines how a Korean scientist who was in the periphery of virology could go into the central area of virology. Also this article shows the process through which the virus found by Ho Wang Lee was registered with the international academia and he proceeded with follow-up research based on this progress to reach the level at which he generalized epidemic hemorrhagic fever related studies throughout the world. While he was conducting the studies, experimental methods that he had never experienced encountered him as new difficulties. He tried to solve the new difficulties faced in his changed status through devices of cooperation and connection. Ho Wang Lee's growth as a researcher can be seen as well as a view of a researcher that grew from a regional level to an international level and could advance from the area of non-mainstream into the mainstream. This analytic tool is meaningful in that it can be another method of examining the growth process of scientists in South Korea or developing countries.

  20. Prevalência dos tipos sangüíneos A, B e AB em gatos domésticos mestiços da cidade de Porto Alegre, Rio Grande do Sul, Brasil

    Directory of Open Access Journals (Sweden)

    Luciana de Almeida Lacerda

    2008-12-01

    Full Text Available O presente estudo teve como objetivo determinar a prevalência dos tipos sangüíneos em felinos domésticos, mestiços, da cidade de Porto Alegre, Rio Grande do Sul, Brasil. Foram selecionados aleatoriamente 100 gatos, clinicamente saudáveis, mestiços e sem parentesco entre si. Amostras de sangue foram coletadas da veia jugular e a tipagem sangüínea foi realizada através do teste RapidVet H Feline (DMS Laboratories, Flemington, USA e do teste hemaglutinação em tubo de ensaio. A tipagem reversa foi realizada para confirmar o tipo e a presença de aloanticorpos naturais. No presente estudo encontrou-se prevalência de 97% e 3% de gatos do tipo A e B, respectivamente. Não foram encontrados gatos do tipo AB. Os resultados indicam que no sul do Brasil há uma alta prevalência de gatos domésticos mestiços do tipo A, entretanto a prevalência de gatos do tipo B encontrada no trabalho é mais alta do que aquelas relatadas em alguns países. O conhecimento da prevalência dos tipos sangüíneos da população de gatos de uma região pode auxiliar na determinação dos riscos de reações transfusionais e de ocorrência de isoeritrólise neonatal, e estes podem ser prevenidos através de tipagem sangüínea e teste de compatibilidade sangüínea.

  1. Outlining the influence of non-conventional yeasts in wine ageing over lees.

    Science.gov (United States)

    Belda, Ignacio; Navascués, Eva; Marquina, Domingo; Santos, Antonio; Calderón, Fernando; Benito, Santiago

    2016-07-01

    During the last decade, the use of innovative yeast cultures of both Saccharomyces cerevisiae and non-Saccharomyces yeasts as alternative tools to manage the winemaking process have turned the oenology industry. Although the contribution of different yeast species to wine quality during fermentation is increasingly understood, information about their role in wine ageing over lees is really scarce. This work aims to analyse the incidence of three non-Saccharomyces yeast species of oenological interest (Torulaspora delbrueckii, Lachancea thermotolerans and Metschnikowia pulcherrima) and of a commercial mannoprotein-overproducer S. cerevisiae strain compared with a conventional industrial yeast strain during wine ageing over lees. To evaluate their incidence in mouthfeel properties of wine after 4 months of ageing, the mannoprotein content of wines was evaluated, together with other wine analytic parameters, such as colour and aroma, biogenic amines and amino acids profile. Some differences among the studied parameters were observed during the study, especially regarding the mannoprotein concentration of wines. Our results suggest that the use of T. delbrueckii lees in wine ageing is a useful tool for the improvement of overall wine quality by notably increasing mannoproteins, reaching values higher than obtained using a S. cerevisiae overproducer strain. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  2. An unusual feature associated with LEE1 P1 promoters in enteropathogenic Escherichia coli (EPEC).

    Science.gov (United States)

    Jeong, Jae-Ho; Kim, Hyun-Ju; Kim, Kun-Hee; Shin, Minsang; Hong, Yeongjin; Rhee, Joon Haeng; Schneider, Thomas D; Choy, Hyon E

    2012-02-01

    Transcription start points in bacteria are influenced by the nature of the RNA polymerase·promoter interaction. For Escherichia coli RNA polymerase holoenzyme containing σ70, it is presumed that specific sequence in one or more of the -10, extended -10 and -35 elements of the promoter guides the RNAP to select the cognate start point. Here, we investigated the promoter driving expression of the LEE1 operon in enteropathogenic E. coli and found two promoters separated by 10 bp, LEE1 P1A (+1) and LEE1 P1B (+10) using various in vitro biochemical tools. A unique feature of P1B was the presence of multiple transcription starts from five neighbouring As at the initial transcribed region. The multiple products did not arise from stuttering synthesis. Analytical software based on information theory was employed to determine promoter elements. The concentration of the NTP pool altered the preferred transcription start points, albeit the underlying mechanism is elusive. Under in vivo conditions, dominant P1B, but not P1A, was subject to regulation by IHF. © 2012 Blackwell Publishing Ltd.

  3. Observation of Mountain Lee Waves with MODIS NIR Column Water Vapor

    Science.gov (United States)

    Lyapustin, A.; Alexander, M. J.; Ott, L.; Molod, A.; Holben, B.; Susskind, J.; Wang, Y.

    2014-01-01

    Mountain lee waves have been previously observed in data from the Moderate Resolution Imaging Spectroradiometer (MODIS) "water vapor" 6.7 micrometers channel which has a typical peak sensitivity at 550 hPa in the free troposphere. This paper reports the first observation of mountain waves generated by the Appalachian Mountains in the MODIS total column water vapor (CWV) product derived from near-infrared (NIR) (0.94 micrometers) measurements, which indicate perturbations very close to the surface. The CWV waves are usually observed during spring and late fall or some summer days with low to moderate CWV (below is approx. 2 cm). The observed lee waves display wavelengths from3-4 to 15kmwith an amplitude of variation often comparable to is approx. 50-70% of the total CWV. Since the bulk of atmospheric water vapor is confined to the boundary layer, this indicates that the impact of thesewaves extends deep into the boundary layer, and these may be the lowest level signatures of mountain lee waves presently detected by remote sensing over the land.

  4. Forecasting the mortality rates using Lee-Carter model and Heligman-Pollard model

    Science.gov (United States)

    Ibrahim, R. I.; Ngataman, N.; Abrisam, W. N. A. Wan Mohd

    2017-09-01

    Improvement in life expectancies has driven further declines in mortality. The sustained reduction in mortality rates and its systematic underestimation has been attracting the significant interest of researchers in recent years because of its potential impact on population size and structure, social security systems, and (from an actuarial perspective) the life insurance and pensions industry worldwide. Among all forecasting methods, the Lee-Carter model has been widely accepted by the actuarial community and Heligman-Pollard model has been widely used by researchers in modelling and forecasting future mortality. Therefore, this paper only focuses on Lee-Carter model and Heligman-Pollard model. The main objective of this paper is to investigate how accurately these two models will perform using Malaysian data. Since these models involves nonlinear equations that are explicitly difficult to solve, the Matrix Laboratory Version 8.0 (MATLAB 8.0) software will be used to estimate the parameters of the models. Autoregressive Integrated Moving Average (ARIMA) procedure is applied to acquire the forecasted parameters for both models as the forecasted mortality rates are obtained by using all the values of forecasted parameters. To investigate the accuracy of the estimation, the forecasted results will be compared against actual data of mortality rates. The results indicate that both models provide better results for male population. However, for the elderly female population, Heligman-Pollard model seems to underestimate to the mortality rates while Lee-Carter model seems to overestimate to the mortality rates.

  5. Lee Miller à travers la Roumanie, l’appareil photo à la main (1946

    Directory of Open Access Journals (Sweden)

    Adrian-Silvan Ionescu

    2012-01-01

    Full Text Available A former model and fashion photographer turned war photographer, Lee Miller visited Romania twice, in 1938 and 1946 respectively. After her second visit she published her impressions and pictures, under the title of Roumania, in Vogue magazine. Besides the published material there are her manuscripts from The Lee Miller Achives at Farley Farm House, East Sussex, England, on which this paper is based. She crossed the border coming from Hungary in early February 1946. Heading for Sibiu her car, a Chevrolet Sedan, slipping on the ice-covered road, stopped on a snowbank far off in the ditch. While looking for help in the nearby village she and her companions left the car unguarded to discover it plundered of everything, wheels included.On a Sunday afternoon she had the privilege of being received by King Mihai I and Queen Mother Elena with whom she talked exstensively. She also took magnificent pictures with the Royal Family in the imposing Peleş Castle. At Sinaia, „the summer capital of Roumania” she had also the opportunity to portray Dinu Brătianu and Iuliu Maniu, the two elderly statesmen. Maniu was surrounded by friends and party members, among whom was young Corneliu Coposu, his private secretary.Moving to Bucharest, she met old friends such as Harri Brauner and his wife, Lena Constante, with whom she wandered through the country eight years ago. Lena and Elena Pătrășcanu, wife of Lucrețiu Pătrășcanu, Minister of Justice, have started a successful marionette theatre where Lee took nice pictures. Other were taken on the streets, with peasants, street vendors and their customers. Harri took her to a bistro where they met Maria Lătărețu, the celebrating folk singer whom Brauner recorded many times. They enjoyed her songs. Suffering from fibrositis, Lee Miller undertook a peculiar treatment in a gypsy village where the inhabitants were dancing bears trainers. She was massaged by a bear weighing about 300 pounds while Brauner took

  6. 78 FR 77508 - Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined...

    Science.gov (United States)

    2013-12-23

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined Licenses Application Review AGENCY: Nuclear Regulatory Commission. ACTION: Final environmental impact...

  7. H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Jonathan A Levine

    Full Text Available Enteropathogenic E. coli (EPEC and enterohemorrhagic E. coli are important causes of morbidity and mortality worldwide. These enteric pathogens contain a type III secretion system (T3SS responsible for the attaching and effacing (A/E lesion phenotype. The T3SS is encoded by the locus of enterocyte effacement (LEE pathogenicity island. The H-NS-mediated repression of LEE expression is counteracted by Ler, the major activator of virulence gene expression in A/E pathogens. A regulator present in EPEC, H-NST, positively affects expression of H-NS regulon members in E. coli K-12, although the effect of H-NST on LEE expression and virulence of A/E pathogens has yet-to-be determined.We examine the effect of H-NST on LEE expression and A/E lesion formation on intestinal epithelial cells. We find that H-NST positively affects the levels of LEE-encoded proteins independently of ler and induces A/E lesion formation. We demonstrate H-NST binding to regulatory regions of LEE1 and LEE3, the first report of DNA-binding by H-NST. We characterize H-NST mutants substituted at conserved residues including Ala16 and residues Arg60 and Arg63, which are part of a potential DNA-binding domain. The single mutants A16V, A16L, R60Q and the double mutant R60Q/R63Q exhibit a decreased effect on LEE expression and A/E lesion formation. DNA mobility shift assays reveal that these residues are important for H-NST to bind regulatory LEE DNA targets. H-NST positively affects Ler binding to LEE DNA in the presence of H-NS, and thereby potentially helps Ler displace H-NS bound to DNA.H-NST induces LEE expression and A/E lesion formation likely by counteracting H-NS-mediated repression. We demonstrate that H-NST binds to DNA and identify arginine residues that are functionally important for DNA-binding. Our study suggests that H-NST provides an additional means for A/E pathogens to alleviate repression of virulence gene expression by H-NS to promote virulence capabilities.

  8. H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.

    Science.gov (United States)

    Levine, Jonathan A; Hansen, Anne-Marie; Michalski, Jane M; Hazen, Tracy H; Rasko, David A; Kaper, James B

    2014-01-01

    Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of morbidity and mortality worldwide. These enteric pathogens contain a type III secretion system (T3SS) responsible for the attaching and effacing (A/E) lesion phenotype. The T3SS is encoded by the locus of enterocyte effacement (LEE) pathogenicity island. The H-NS-mediated repression of LEE expression is counteracted by Ler, the major activator of virulence gene expression in A/E pathogens. A regulator present in EPEC, H-NST, positively affects expression of H-NS regulon members in E. coli K-12, although the effect of H-NST on LEE expression and virulence of A/E pathogens has yet-to-be determined. We examine the effect of H-NST on LEE expression and A/E lesion formation on intestinal epithelial cells. We find that H-NST positively affects the levels of LEE-encoded proteins independently of ler and induces A/E lesion formation. We demonstrate H-NST binding to regulatory regions of LEE1 and LEE3, the first report of DNA-binding by H-NST. We characterize H-NST mutants substituted at conserved residues including Ala16 and residues Arg60 and Arg63, which are part of a potential DNA-binding domain. The single mutants A16V, A16L, R60Q and the double mutant R60Q/R63Q exhibit a decreased effect on LEE expression and A/E lesion formation. DNA mobility shift assays reveal that these residues are important for H-NST to bind regulatory LEE DNA targets. H-NST positively affects Ler binding to LEE DNA in the presence of H-NS, and thereby potentially helps Ler displace H-NS bound to DNA. H-NST induces LEE expression and A/E lesion formation likely by counteracting H-NS-mediated repression. We demonstrate that H-NST binds to DNA and identify arginine residues that are functionally important for DNA-binding. Our study suggests that H-NST provides an additional means for A/E pathogens to alleviate repression of virulence gene expression by H-NS to promote virulence capabilities.

  9. 'Items for criticism (not in sequence)': Joseph DeLee, Pare Lorentz and The Fight for Life (1940).

    Science.gov (United States)

    Gainty, Caitjan

    2017-09-01

    In the late 1920s, the American obstetrician Joseph DeLee brought the motion-picture camera into the birth room. Following that era's trend of adapting industrial efficiency practices for medical environments, DeLee's films give spectacular and unexpected expression to the engineering concept of 'streamlining'. Accomplishing what more tangible obstetric streamlining practices had failed to, DeLee's cameras, and his post-production manipulation, shifted birth from messy and dangerous to rationalized, efficient, death-defying. This was film as an active and effective medical tool. Years later, the documentarian Pare Lorentz produced and wrote his own birth film, The Fight for Life (1940). The documentary subject of the film was DeLee himself, and the film was set in his hospitals, on the same maternity 'sets' that had once showcased film's remarkable streamlining capacity to give and keep life. Yet relatively little of DeLee was retained in the film's content, resulting in a showdown that, by way of contrast, further articulated DeLee's understanding of film's medical powers and, in so doing, hinted at a more dynamic moment in the history of medicine while speaking also to the process by which that understanding ceased to be historically legible.

  10. Potential of lees from wine, beer and cider manufacturing as a source of economic nutrients: An overview.

    Science.gov (United States)

    Pérez-Bibbins, B; Torrado-Agrasar, A; Salgado, J M; Oliveira, R Pinheiro de Souza; Domínguez, J M

    2015-06-01

    Lees are the wastes generated during the fermentation and aging processes of different industrial activities concerning alcoholic drinks such as wine, cider and beer. They must be conveniently treated to avoid uncontrolled dumping which causes environmental problems due to their high content of phenols, pesticides, heavy metals, and considerable concentrations of nitrogen, phosphate and potassium as well as high organic content. The companies involved must seek alternative environmental and economic physicochemical and biological treatments for their revalorization consisting in the recovery or transformation of the components of the lees into high value-added compounds. After describing the composition of lees and market of wine, beer and cider industries in Spain, this work aims to review the recent applications of wine, beer and cider lees reported in literature, with special attention to the use of lees as an endless sustainable source of nutrients and the production of yeast extract by autolysis or cell disruption. Lees and/or yeast extract can be used as nutritional supplements with potential exploitation in the biotechnological industry for the production of natural compounds such as xylitol, organic acids, and biosurfactants, among others. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Generation of hyperchaos from the Chen-Lee system via sinusoidal perturbation

    Energy Technology Data Exchange (ETDEWEB)

    Tam, L.M. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Thomas Pereira S.J., Taipa, Macau (China)], E-mail: fstlmt@umac.mo; Chen, J.H. [Department of Mechanical Engineering, Chung Hua University, Hsinchu, Taiwan (China); Chen, H.K. [Department of Mechanical Engineering, Hsiuping Institute of Technology, Taichung, Taiwan (China); Wai Meng Si Tou [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Thomas Pereira S.J., Taipa, Macau (China)

    2008-11-15

    A system with more than one positive Lyapunov exponent can be classified as a hyperchaotic system. In this study, a sinusoidal perturbation was designed for generating hyperchaos from the Chen-Lee chaotic system. The hyperchaos was identified by the existence of two positive Lyapunov exponents and bifurcation diagrams. The system is hyperchaotic in several different regions of the parameters c, {epsilon}, and {omega}. It was found that this method not only can enhance or suppress chaotic behavior, but also induces chaos in non-chaotic parameter ranges. In addition, two interesting dynamical behaviors, Hopf bifurcation and intermittency, were also found in this study.

  12. Adaptation of Sing Lee's model to the Filippov type plasma focus geometry

    International Nuclear Information System (INIS)

    Siahpoush, V; Tafreshi, M A; Sobhanian, S; Khorram, S

    2005-01-01

    A new model for plasma behaviour in Filippov type plasma focus (PF) systems has been described and used. This model is based on the so-called slug model and Sing Lee's model for Mather type PF devices. Using the model, the discharge current and its derivative as a function of time, and the pinch time and the maximum discharge current as a function of pressure, have been predicted. At the end, the predicted data are compared with the experimental data obtained through a Filippov type PF facility with a nominal maximum energy of 90 kJ

  13. ”I sangen møtes vi på felles grunn.” Om sang og sangbøker i norsk skole.

    Directory of Open Access Journals (Sweden)

    Ragnhild Elisabeth Lund

    2010-12-01

    Full Text Available Sangfaget har en lang og sterk tradisjon i den norske skolestua og sangboka har vært et sentralt læremiddel i mer enn 150 år. Formålet med denne artikkelen er å belyse de mange og ulike begrunnelser som er blitt knyttet til faget opp gjennom tidene og å vise hvilket innhold sangbøkene har søkt å formidle. Presentasjonen av sangfagets begrunnelser er basert på en undersøkelse av skolehistoriske tekster og læreplaner fra tidlig på 1800-tallet fram til vår tid. Jeg har også sett på forordene og forfatternes vektlegging av sangrepertoar og annet sang- og musikkfaglig innhold i de mest toneangivende sangbøkene fra samme periode. For å finne ut hvilke sanger elevene er blitt tilbudt og hvilke verdier sangene formidler, har jeg kartlagt repertoarvalget i tolv sangbokverk fra 1850 (Behrens’ Skolesangbog til 2008 (Amsrud & Bjørnstads Sang i Norge. Artikkelen viser at begrunnelsene for sangfaget favner vidt og at både de og innholdet i sangbøkene har endret seg i takt med utviklingen i utdanningssystemet og i samfunnet forøvrig. Videreformidling av sentrale sanger i norsk kulturarv har selvsagt stått sentralt. Men sangfaget har også befattet seg med opplæring i musikkteori, notelære og stemmepleie, og det har hatt som oppgave å utvikle kvalitetsbevissthet, samhold og fellesskap i tillegg til å bidra til læring og trivsel i andre fag. Når det gjelder repertoarvalg, har utviklingen gått fra en hovedvekt på sanger med et religiøst og oppdragende innhold via nasjonale sanger til en stadig økende andel ”blott-til-lyst-sanger” og sanger fra populærmusikkens område. Til tross for at repertoarvalget har endret seg, er det mange sanger som går igjen gjennom hele perioden. Med referanse til en definisjon av kanon som ”stabile forekomster” identifiserer artikkelen 34 sanger som kan sies å utgjøre en del av ”den norske sangskatten”.

  14. Desvios porta-jugular e cava-jugular passivos em cães: Investigação de pressões sangüíneas

    Directory of Open Access Journals (Sweden)

    Coelho Antônio Roberto Barros

    1999-01-01

    Full Text Available Os principais objetivos dos desvios veno-venosos durante o transplante ortotópico de fígado são: atenuação da estase venosa subdiafragmática, manutenção do retorno satisfatório de sangue ao coração e perfusão tissular eficiente. Investigações sobre PP, PVCIIH, PVC, PAM e PPR, bem como D PP e D PVCIIH foram conduzidas em seis cães, sob anestesia geral, com fígados perfundidos pela Artéria Hepática, submetidos a desvios porta-jugular e cava-jugular passivos durante 2 horas. Estes desvios não foram capazes de evitar estagnação de sangue na VP e VCIIH, acarretando estase e menor retorno sangüíneo ao coração, sugeridos por aumentos significativos de PP e PVCIIH e quedas significantes nos níveis de PVC. Os valores de PAM não apresentaram diferenças significativas em relação ao tempo T0, na maior parte dos tempos avaliados, enquanto que os valores de PPR foram significativamente menores que os verificados no tempo T0, na maioria dos tempos estudados. Tais pressões mantiveram-se, respectivamente, acima de 100 e 50 mm de Hg, atribuindo-se tais resultados, em parte, à vasoconstricção arteriolar generalizada. Incrementos de pressão na VP (D PP foram significativamente menos elevados que aqueles verificados na VCIIH (D PVCIIH, atribuindo-se tal diferença à complacência esplâncnica. Decréscimos ulteriores dos níveis de PP e PVCIIH sugerem queda do fluxo arterial para os territórios esplâncnico e sistêmico, decorrente de diminuição do retorno sangüíneo ao coração. Determinações de PP, PVCIIH, PVC, PAM e PPR podem constituir meio prático de avaliação hemodinâmica do desvio veno-venoso.

  15. Physicochemical aspects of decomposition of silica-alumina ores of argillites and green clays of Chashma-Sang Deposit of the Republic of Tajikistan by hydrochloric and nitric acids

    International Nuclear Information System (INIS)

    Kayumov, A.M.

    2018-01-01

    The purpose of work is to study the processes of decomposition of silica-alumina ores of argillites and green clays of Chashma-Sang Deposit of the Republic of Tajikistan by hydrochloric and nitric acids in temperature interval 20-98 deg C with the using of methods of selective extraction of valuable materials; elaboration of rational conditions of decomposition of raw material. Physicochemical properties of initial aluminium comprising ores, intermediate and final products of processing of argillites and green clays have been studied. Kinetic parameters of processes at acidic decomposition of argillites and green clays have been studied as well. The kinetic parameters of processes of decomposition of green clays and argillites by nitric and hydrochloric acids have been calculated. The flowsheet of complex processing of green clays and argillites of Chashma-Sang Deposit has been elaborated.

  16. Visioni vittoriane: il paesaggio fiorentino nelle opere di Janet Ross e Vernon Lee

    Directory of Open Access Journals (Sweden)

    Gabriele Corsani

    2015-11-01

    Full Text Available Fra l’ultimo scorcio dell’Ottocento e i primi decenni del Novecento Firenze e i suoi dintorni sono il soggetto privilegiato di una grande quantità di descrizioni, note di diario, racconti, opera di scrittori stranieri, in particolare inglesi, che si radicano nell’approdo elettivo di quei luoghi. Il testo presenta la traccia letteraria del paesaggio fiorentino nelle opere di Vernon Lee e Janet Ross, due tipiche rappresentanti di questa tendenza che hanno vissuto, attraverso vicende biografiche in qualche modo parallele, un’esperienza di intensa identificazione con il paesaggio fiorentino. Di Janet Ross, viene commentato Old Florence and Modern Tuscany, volume che raccoglie una serie di articoli pubblicati su alcune riviste inglesi e fornisce una efficace panoramica sull’interesse molto concreto di Janet Ross per il mondo rurale che la vede addirittura impegnata nella gestione della fattoria di Castagnolo, a Lastra a Signa. Più sfaccettato è il commento alle opere di Vernon Lee, di cui sono commentati passi da Vanitas. Polite Stories, Genius Loci, Hortus Vitae and Limbo, in virtù della maggiore ampiezza e complessità del suo mondo culturale. Ne sono cifra distintiva la associazione fra storia e realtà attraverso la dimensione del mistero, che risulta una delle chiavi di acccesso alla bellezza e alla vitalità del paesagggio e la capacità di cogliere il ritmo proprio dei luoghi e di entrare in reale sintonia con essi. 

  17. Electricity generation using white and red wine lees in air cathode microbial fuel cells

    Science.gov (United States)

    Pepe Sciarria, Tommy; Merlino, Giuseppe; Scaglia, Barbara; D'Epifanio, Alessandra; Mecheri, Barbara; Borin, Sara; Licoccia, Silvia; Adani, Fabrizio

    2015-01-01

    Microbial fuel cell (MFC) is a useful biotechnology to produce electrical energy from different organic substrates. This work reports for the first time results of the application of single chamber MFCs to generate electrical energy from diluted white wine (WWL) and red wine (RWL) lees. Power obtained was of 8.2 W m-3 (262 mW m-2; 500 Ω) and of 3.1 W m-3 (111 mW m-2; 500Ω) using white and red wine lees, respectively. Biological processes lead to a reduction of chemical oxygen (TCOD) and biological oxygen demand (BOD5) of 27% and 83% for RWL and of 90% and 95% for WWL, respectively. These results depended on the degradability of organic compounds contained, as suggest by BOD5/TCOD of WWL (0.93) vs BOD5/TCOD of RWL (0.33), and to the high presence of polyphenols in RWL that inhibited the process. Coulombic efficiency (CE) of 15 ± 0%, for WWL, was in line with those reported in the literature for other substrates, i.e. CE of 14.9 ± 11.3%. Different substrates led to different microbial consortia, particularly at the anode. Bacterial species responsible for the generation of electricity, were physically connected to the electrode, where the direct electron transfer took place.

  18. Grape marc, wine lees and deposit of the must: How to manage oenological by-products?

    Directory of Open Access Journals (Sweden)

    Lempereur Valérie

    2014-01-01

    Full Text Available Winemaking produces solid (grape marc and liquid (wine lees and deposit of the must wastes named “oenological by-products”, which, according to European regulations, must be eliminated following the environmental regulatory requirement [1]. In France, these European regulations forced wine growers, until the 2013/2014 campaign, to deliver all by-products to wine distilleries. This French obligation is known as the “prestation vinique” [2, 3]. Following the Common Market Organisation wine reform, a consultation was initiated by FranceAgriMer on the potential value of oenological by-products. The French Institute of Vine and Wine (IFV coordinated a national experimentation from 2010 to 2013 about recovery of by-products, with the support of members of the Technical Group: Association des Viticulteurs d'Alsace (AVA, Comité Interprofessionnel du Vin de Champagne (CIVC, Institut Technique des Corps Gras (ITERG, et Union Nationale des Groupements de Distillateurs d'Alcool (UNGDA. Distillation of grape marc and wine lees spreading and composting, and anaerobic digestion of grape marc were studied in order to answer the following questions: What technical feasibility? What environmental impact? What cost for winegrowers? What conformity with the regulations, including environmental regulatory obligations? [4].

  19. South Korean Government under the former CEO, President Lee Myung-bak

    Directory of Open Access Journals (Sweden)

    Eunsook Yang

    2008-10-01

    Full Text Available Tras un prometedor inicio gracias a su arrolladora victoria en diciembre del 2007 y portando un mandato para llevar a cabo profundas reformas económicas, el presidente Lee Myung-bak se ha visto obligado a recuperar la confianza de su ciudadanía tras las duras críticas a numerosos aspectos de su política: la importación de carne vacuna bajo el Tratado de Libre Comercio EEUU-Corea del Sur pendiente de aprobación, sus ambiciosos proyectos de construcción, su agenda de privatizaciones y su estilo algo autoritario. Las características de su política exterior resultan interesantes por los contrastes con su predecesor: refuerzo de la alianza con los EEUU, mejora de las relaciones con Japón, mayor dinamismo en su diplomacia energética hacia Rusia, mayor envergadura a su relación con China y una postura más firme hacia Corea del Norte. Sin embargo Lee Myung-bak ha de superar el desafío que la crisis económica mundial le presenta y así poder restaurar la situación económica de su país.

  20. Vitis vinifera L. cv Pinot noir pomace and lees as potential sources of bioactive compounds.

    Science.gov (United States)

    Reis, Gabriel M; Faccin, Henrique; Viana, Carine; Rosa, Marcelo Barcellos da; de Carvalho, Leandro M

    2016-11-01

    Food and agricultural industries generate substantial quantities of phenolic-rich by-products that could be valuable natural sources of antioxidants. The aim of this study was to identify and quantify the phenolic compounds and radical scavenging activities of two by-products (pomace and lees) from Vitis vinifera L. cv Pinot noir. We found a different distribution of phenolic classes (flavanols, flavonols, phenolic acids and stilbenes) and singular scavenging activity against free radicals (hydroxyl, superoxide and peroxyl radicals). The major class of phenolics in pomace was flavanols and in lees was flavonols, with catechin (117.9 ± 2.5 μg g(-1)) and quercetin (42.4 ± 1.2 μg g(-1)) being the most abundant individual compounds. We also found high potential on scavenging activity against superoxide radicals in pomace (80% of scavenging activity) and radical peroxyl (67% scavenging activity). These results show the possibility of using Pinot noir by-products as promising additives or as a source for the development of new products in different segments of the food and cosmetic industries.

  1. Nonsingular cosmology with a scale-invariant spectrum of cosmological perturbations from Lee-Wick theory

    International Nuclear Information System (INIS)

    Cai Yifu; Qiu Taotao; Brandenberger, Robert; Zhang Xinmin

    2009-01-01

    We study the cosmology of a Lee-Wick type scalar field theory. First, we consider homogeneous and isotropic background solutions and find that they are nonsingular, leading to cosmological bounces. Next, we analyze the spectrum of cosmological perturbations which result from this model. Unless either the potential of the Lee-Wick theory or the initial conditions are finely tuned, it is impossible to obtain background solutions which have a sufficiently long period of inflation after the bounce. More interestingly, however, we find that in the generic noninflationary bouncing cosmology, perturbations created from quantum vacuum fluctuations in the contracting phase have the correct form to lead to a scale-invariant spectrum of metric inhomogeneities in the expanding phase. Since the background is nonsingular, the evolution of the fluctuations is defined unambiguously through the bounce. We also analyze the evolution of fluctuations which emerge from thermal initial conditions in the contracting phase. The spectrum of gravitational waves stemming from quantum vacuum fluctuations in the contracting phase is also scale-invariant, and the tensor to scalar ratio is not suppressed.

  2. Polyphenols from Wine Lees as a Novel Functional Bioactive Compound in the Protection Against Oxidative Stress and Hyperlipidaemia

    Directory of Open Access Journals (Sweden)

    Irena Landeka Jurčević

    2017-01-01

    Full Text Available The study examines the potential of wine industry by-product, the lees, as a rich mixture of natural polyphenols, and its physiological potential to reduce postprandial metabolic and oxidative stress caused by a cholesterol-rich diet in in vivo model. Chemical analysis of wine lees showed that their total solid content was 94.2 %. Wine lees contained total phenols, total nonflavonoids and total flavonoids expressed in mg of gallic acid equivalents per 100 g of dry mass: 2316.6±37.9, 1332.5±51.1 and 984.1±28.2, respectively. The content of total anthocyanins expressed in mg of cyanidin-3-glucoside equivalents per 100 g of dry mass was 383.1±21.6. Antioxidant capacity of wine lees determined by the DPPH and FRAP methods and expressed in mM of Trolox equivalents per 100 g was 259.8±1.8 and 45.7±1.05, respectively. The experiment lasted 60 days using C57BL/6 mice divided in four groups: group 1 was fed normal diet and used as control, group 2 was fed normal diet with added wine lees, group 3 was fed high-cholesterol diet (HCD, i.e. normal diet with the addition of sunflower oil, and group 4 was fed HCD with wine lees. HCD increased serum total cholesterol (TC by 2.3-fold, triacylglycerol (TAG by 1.5-fold, low-density lipoprotein (LDL by 3.5-fold and liver malondialdehyde (MDA by 50 %, and reduced liver superoxide dismutase (SOD by 50 %, catalase (CAT by 30 % and glutathione (GSH by 17.5 % compared to control. Conversely, treatment with HCD and wine lees reduced TC and LDL up to 1.4 times more than with HCD only, with depletion of lipid peroxidation (MDA and restoration of SOD and CAT activities in liver, approximating values of the control. HDL levels were unaffected in any group. Serum transaminase activity showed no hepatotoxic properties in the treatment with lees alone. In the proposed model, wine lees as a rich polyphenol source could be a basis for functional food products without alcohol.

  3. Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE) Pathogenicity Island in EnteropathogenicEscherichia coli.

    Science.gov (United States)

    Leh, Hervé; Khodr, Ahmad; Bouger, Marie-Christine; Sclavi, Bianca; Rimsky, Sylvie; Bury-Moné, Stéphanie

    2017-08-08

    In enteropathogenic Escherichia coli (EPEC), the locus of enterocyte effacement (LEE) encodes a type 3 secretion system (T3SS) essential for pathogenesis. This pathogenicity island comprises five major operons ( LEE1 to LEE5 ), with the LEE5 operon encoding T3SS effectors involved in the intimate adherence of bacteria to enterocytes. The first operon, LEE1 , encodes Ler (LEE-encoded regulator), an H-NS (nucleoid structuring protein) paralog that alleviates the LEE H-NS silencing. We observed that the LEE5 and LEE1 promoters present a bimodal expression pattern, depending on environmental stimuli. One key regulator of bimodal LEE1 and LEE5 expression is ler expression, which fluctuates in response to different growth conditions. Under conditions in vitro considered to be equivalent to nonoptimal conditions for virulence, the opposing regulatory effects of H-NS and Ler can lead to the emergence of two bacterial subpopulations. H-NS and Ler share nucleation binding sites in the LEE5 promoter region, but H-NS binding results in local DNA structural modifications distinct from those generated through Ler binding, at least in vitro Thus, we show how two nucleoid-binding proteins can contribute to the epigenetic regulation of bacterial virulence and lead to opposing bacterial fates. This finding implicates for the first time bacterial-chromatin structural proteins in the bimodal regulation of gene expression. IMPORTANCE Gene expression stochasticity is an emerging phenomenon in microbiology. In certain contexts, gene expression stochasticity can shape bacterial epigenetic regulation. In enteropathogenic Escherichia coli (EPEC), the interplay between H-NS (a nucleoid structuring protein) and Ler (an H-NS paralog) is required for bimodal LEE5 and LEE1 expression, leading to the emergence of two bacterial subpopulations (with low and high states of expression). The two proteins share mutual nucleation binding sites in the LEE5 promoter region. In vitro , the binding of H

  4. Determination du niveau d'anticorps antitetaniques en donneurs de sang au moyen du test ELISA-TÉTANOS (São Paulo, SP, Bresil

    Directory of Open Access Journals (Sweden)

    Luzia Cristina Contim Ferrato

    1990-12-01

    Full Text Available Le test ELISA-TÉTANOS (Biosys, France a été utilisé pour le titrage des anti-corps tétaniques (sensibilité = 0,0025 UI/ml en sérums humains de donneurs de sang, 566 hommes et 108 femmes, âges de 18 à 58 ans, moyenne de 29 ans, provenant de São Paulo, SP, Brésil. L'OMS, acceptant seulement la séroneutralisation sur souris (NT, la méthode de référence, pour les études sur la protection contre le tétanos, préconise le titre de 0,01 UI/ml comme minimum protecteur. BOURLEAUD & HUET ont proposé la limite de 0,06 UI/ml quand s'emploie le test ELISA, en attendant à une certaine discordance inévitable entre les méthodes. Parmi les 674 sérums étudiés, 178 (26,41% n'ont pas présenté d'anticorps ( 0,06 UI/ml.

  5. RcsB determines the locus of enterocyte effacement (LEE) expression and adherence phenotype of Escherichia coli O157 : H7 spinach outbreak strain TW14359 and coordinates bicarbonate-dependent LEE activation with repression of motility.

    Science.gov (United States)

    Morgan, Jason K; Vendura, Khoury W; Stevens, Stanley M; Riordan, James T

    2013-11-01

    The 2006 US spinach outbreak of Escherichia coli O157 : H7, characterized by unusually severe disease, has been attributed to a strain (TW14359) with enhanced pathogenic potential, including elevated virulence gene expression, robust adherence and the presence of novel virulence factors. This study proposes a mechanism for the unique virulence expression and adherence phenotype of this strain, and further expands the role for regulator RcsB in control of the E. coli locus of enterocyte effacement (LEE) pathogenicity island. Proteomic analysis of TW14359 revealed a virulence proteome consistent with previous transcriptome studies that included elevated levels of the LEE regulatory protein Ler and type III secretion system (T3SS) proteins, secreted T3SS effectors and Shiga toxin 2. Basal levels of the LEE activator and Rcs phosphorelay response regulator, RcsB, were increased in strain TW14359 relative to O157 : H7 strain Sakai. Deletion of rcsB eliminated inherent differences between these strains in ler expression, and in T3SS-dependent adherence. A reciprocating regulatory pathway involving RcsB and LEE-encoded activator GrlA was identified and predicted to co-ordinate LEE activation with repression of the flhDC flagellar regulator and motility. Overexpression of grlA was shown to increase RcsB levels, but did not alter expression from promoters driving rcsB transcription. Expression of rcsDB and RcsB was determined to increase in response to physiological levels of bicarbonate, and bicarbonate-dependent stimulation of the LEE was shown to be dependent on an intact Rcs system and ler activator grvA. The results of this study significantly broaden the role for RcsB in enterohaemorrhagic E. coli virulence regulation.

  6. Interpretation for ''high''-Tc of the totally interconnected solution of the Ma and Lee model

    International Nuclear Information System (INIS)

    Wiecko, C.

    1988-09-01

    The already presented totally interconnected (mean-field) approximation of the Ma and Lee model, pictures very well many ingredients of the present status of comprehension of high-T c superconductors. The picture is that of a disordered grain with variable number of particles available for an attractive on-site pairing interaction, embedded in a reservoir of normal particles which fix the chemical potential. Interesting effect of absence of T c and then a sharp increase and slow decay of T c with disorder appears for weak coupling pairing as compared with the hopping probability for single particles. Interpretation is given in terms of one-particle Anderson localization theory and standard mechanisms. (author). 13 refs, 4 figs

  7. Lee-Yang-inspired functional with a density-dependent neutron-neutron scattering length

    Science.gov (United States)

    Grasso, M.; Lacroix, D.; Yang, C. J.

    2017-05-01

    Inspired by the low-density Lee-Yang expansion for the energy of a dilute Fermi gas of density ρ and momentum kF, we introduce here a Skyrme-type functional that contains only s -wave terms and provides, at the mean-field level, (i) a satisfactory equation of state for neutron matter from extremely low densities up to densities close to the equilibrium point, and (ii) a good-quality equation of state for symmetric matter at density scales around the saturation point. This is achieved by using a density-dependent neutron-neutron scattering length a (ρ ) which satisfies the low-density limit (for Fermi momenta going to zero) and has a density dependence tuned in such a way that the low-density constraint |a (ρ ) kF|≤1 is satisfied at all density scales.

  8. Vernon Lee in the Vatican: the uneasy alliance of aestheticism and archaeology.

    Science.gov (United States)

    Evangelista, Stefano

    2009-01-01

    From the 1800s onward, aesthetic critics attempted to free the study of ancient Greek art from the frameworks of institutional education and professionalized criticism. In this process, aestheticism entered an uneasy alliance with archaeology, a discipline that was likewise challenging traditional modes of classical learning practiced in public schools and the old universities. In "The Child in the Vatican" (1881), Vernon Lee -- writing under the influence of Pater and from a position of cosmopolitan female amateurism -- examines the uses of archaeological science in the study of classical art. Her analysis of the sculptures of the Niobe Group at once relies on the archaeological method and asks readers to doubt scientific approaches to art that dim the sublime power of the art object.

  9. Enigmatic eight-meter trace fossils in the Lower Pennsylvanian Lee sandstone, central Appalachian basin, Tennessee

    Science.gov (United States)

    Wnuk, C.; Maberry, J.O.

    1990-01-01

    Enigmatic tubular trace fossils up to eight meters long occur in the Lower Pennsylvanian Middlesboro Member of the Lee Formation. Two morphotypes occur: type 1 trace fossils are plain, smooth, vertical, nonbranching, parallel-walled, tubular structures, type 2 trace fossils branch, have walls with faint vertical striations, regularly or irregularly spaced nodes, and funnel-shaped terminations. Sandstone casts filling type 2 structures have helical spiral morphology, and, in rare individuals, faint meniscate fills have been observed. Both trace-fossil morphotypes have poorly cemented wall linings containing framboidal pyrite, amorphous carbon, quartz sand, and poorly preserved fecal material. The trace fossils occur in a massive, structureless, channel-form sandstone, originating at the contact between a channel lag and the overlying massive fill representing a barrier island transgressing an estuarine facies. Origin of these structures is uncertain. -from Authors

  10. The Yang-Lee edge singularity for the Ising model on two Sierpinski fractal lattices

    Energy Technology Data Exchange (ETDEWEB)

    Knezevic, Milan [Faculty of Physics, University of Belgrade, PO Box 368, 11000 Belgrade (Serbia); Knezevic, Dragica, E-mail: knez@ff.bg.ac.r, E-mail: dknezevic@kg.ac.r [Faculty of Natural Sciences and Mathematics, University of Kragujevac, PO Box 60, 34000 Kragujevac (Serbia)

    2010-10-15

    We study the distribution of zeros of the partition function of the ferromagnetic Ising model near the Yang-Lee edge on two Sierpiski-type lattices. We have shown that relevant correlation length displays a logarithmic divergence near the edge, {xi}{sub YL{approx}}|ln({partial_derivative}h)|{sup {Phi}} where {Phi} is a constant and {delta}h distance from the edge, in the case of a modified Sierpinski gasket with a nonuniform coordination number. It is demonstrated that this critical behavior can be related to the critical behavior of a simple zero-field Gaussian model of the same structure. We have shown that there is no such connection between these two models on a second lattice that has a uniform coordination number. These findings suggest that fluctuations of the lattice coordination number of a nonhomogeneous self-similar structure exert the crucial influence on the critical behavior of both models.

  11. Efeitos da Histerectomia Total Abdominal sobre o Fluxo Sangüíneo Ovariano Effect of Total Abdominal Hysterectomy on Ovarian Blood Supply

    Directory of Open Access Journals (Sweden)

    Eliana Aguiar Petri Nahás

    2002-06-01

    Full Text Available Objetivo: avaliar os efeitos da histerectomia total abdominal (HTA sobre o fluxo sangüíneo ovariano, em mulheres no menacme, por meio da dopplervelocimetria e ultra-sonografia transvaginal. Métodos: estudo prospectivo no qual foram incluídas 61 mulheres, com idade igual ou inferior a 40 anos. As pacientes foram divididas em dois grupos: G1, com 31 pacientes submetidas à HTA, e G2, com 30 mulheres normais não submetidas à cirurgia. Somente foram incluídas pacientes eumenorréicas, ovulatórias, não-obesas ou fumantes, sem cirurgias ou doenças ovarianas prévias. Avaliou-se o fluxo sangüíneo das artérias ovarianas, inicialmente e aos 6 e 12 meses, pelo índice de pulsatilidade (IP na dopplervelocimetria, e o volume ovariano pela ultra-sonografia transvaginal (US. Para análise estatística empregou-se teste t pareado, análise de perfil, teste de Friedman e teste de Mann-Whitney. Resultados: na comparação estatística inicial os grupos foram homogêneos quanto às características epidemiológicas e quanto aos demais parâmetros avaliados neste estudo. Nas pacientes submetidas à histerectomia, observaram-se aos 6 e 12 meses aumento do volume ovariano ao US e diminuição do IP avaliado pela dopplervelocimetria (pPurpose: to evaluate the effect of total abdominal hysterectomy on ovarian blood supply in women in reproductive age, using transvaginal color Doppler. Methods: a prospective study was carried out on 61 40-year-old or younger women. They were divided into two groups: G1, 31 patients submitted to hysterectomy, and G2, 30 normal women. Criteria of inclusion: normal ovarian function at baseline, normal body weight, without expasure to tobacco, no history of laparotomy or ovarian pathology. The pulsatility index (PI of ovarian arteries determined by Doppler and the transvaginal ultrasonographic measurement of the ovarian volume were performed at three moments: baseline, 6 and 12 months. Results: at baseline the groups were

  12. Sistema de grupo sangüíneo Duffy: biologia e prática transfusional Duffy blood group system: biology and transfusion practice

    Directory of Open Access Journals (Sweden)

    Eduardo Jens

    2005-06-01

    Full Text Available Após a introdução da técnica de antiglobulina indireta por Coombs em meados da década de 40, vários anticorpos antieritrocitários foram descobertos. O grupo sanguíneo Duffy foi descoberto quando Cutbush e Ikin detectaram, no início da década de 50, os primeiros anticorpos desse sistema. Os anticorpos Duffy são clinicamente significantes na prática transfusional, pois mostraram ser causadores de reação hemolítica transfusional e de doença hemolítica do recém-nascido, sendo de ocorrência mundial. O gene FY é constituído por dois exons e seu lócus foi mapeado no cromossomo 1q22-q23. Os antígenos Fyª e Fy b são codificados pelos alelos FYA e FYB e são responsáveis pelos fenótipos Fy(a+b-, Fy(a-b+ e Fy(a+b+. São carreados por uma glicoproteína de 336 aminoácidos também chamada DARC (Duffy Antigen/Receptor for Chemokines, que tem alta afinidade a quimiocinas, sendo também os receptores para Plasmodium vivax. Os polimorfismos relacionados aos seus alelos permitiram o desenvolvimento da técnica de genotipagem por PCR, que é de grande utilidade para a segurança transfusional e incompatibilidade feto-materna. Na última década, inúmeras pesquisas têm sido feitas quanto ao papel biológico dos antígenos de grupos sangüíneos. Nesse artigo iremos revisar o sistema de grupo sangüíneo Duffy, em especial quanto à prática transfusional e suas funções biológicas.After the introduction of the indirect antiglobulin technique by Coombs in the middle of the 1940's, several antibodies have been discovered. Duffy blood group system came to light when Cutbush and Ikin detected the first antibodies related to this system in the beginning of the 1950's. The antibodies of this system are clinically significant in transfusional practice as they have been involved in hemolytic transfusion reactions and hemolytic disease of the newborn, showing them to be of worldwide occurrence. The FY gene is constituted of two exons and its

  13. [Therapeutic applications and promises of cellular and tissue engineering. What strategic choice for the Etablissement Français du Sang?].

    Science.gov (United States)

    Hervé, Patrick

    2007-05-01

    A new medical field, known as regeneration medicine, is developing and attracting more and more researchers and practitioners. Whereas hematopoietic cell-based therapies have already proven their efficacy in numerous--malignant or not--diseases, non-hematopoietic cell-based therapies have not. They can be useful to dozens, if not hundreds, of patients with various disorders, such as cardiopathy, diabetes, some types of cancer, osteoarticular and neurodegenerative disorders. In these fields, numerous clinical applications are possible for mesenchymal stem cells. Cell and tissue (corneas, bone, skin) therapy products require the definition of pharmaceutical standards with new European requirements in terms of quality and safety. The legitimacy of the Etablissement Français du Sang (EFS) in cell and tissue engineering activities is established, it is recognized by most specialists and by regulatory authorities and has been asserted by the orientations of its "contrat d'objectifs et de moyens". An independent committee has been set up by the EFS President to define an EFS-specific strategy. This committee made up of qualified specialists was required to draw up a rational organization plan for these activities, in order for EFS to be in a position to produce cells and tissues according to pharmaceutical standards. The committee proposals are based on economic data and an inventory of existing cell and tissue engineering activities. Public/private partnerships are required and efforts must focus towards the industrial valorization of EFS expertise in R&D activities and staff know-how. Implementing such a new organization requires national management and the cooperation of institutional actors (university hospitals, cancer treatment centers, universities). For the success of this approach, EFS personnel must be convinced of its legitimacy and new skills must be encouraged. With its numerous assets, EFS can be ambitious and assert itself as a major actor in cell and

  14. Anormalidades de fluxo sangüíneo cerebral em indivíduos dependentes de cocaína Cerebral blood flow abnormalities in cocaine dependent subjects

    Directory of Open Access Journals (Sweden)

    Sergio Nicastri

    2000-06-01

    Full Text Available INTRODUÇÃO: Nos últimos anos, tem havido relatos de anormalidades do fluxo sanguíneo cerebral em indivíduos com o abuso de cocaína, detectadas por meio de tomografia computadorizada por emissão de fóton único (SPECT. Esse padrão anormal de perfusão cerebral tem sido associado a prejuízos cognitivos mas não a alterações observáveis por meio de exames de neuroimagem estrutural. Um problema envolvendo a maioria dos trabalhos publicados sobre esse tema é a inclusão de um grande número de usuários de heroína nas amostras estudadas. Essa outra droga também parece afetar o padrão de perfusão cerebral, particularmente durante estados de abstinência. MÉTODOS: Quatorze pacientes dependentes de cocaína (nenhum com uso de opióides e 14 voluntários normais (grupo controle foram submetidos a exames de SPECT com dímero de etil-cisteína marcado com tecnécio-99m. A análise dos exames de SPECT foi realizada por meio de análise visual qualitativa das imagens obtidas (procedimento padrão na prática clínica, realizada por um radiologista não informado sobre o diagnóstico dos indivíduos avaliados. RESULTADOS: A análise visual revelou um padrão sugestivo de irregularidades do fluxo sangüíneo cerebral em nove pacientes, mas em apenas dois controles (p = 0,018; teste exato de Fisher bicaudal. CONCLUSÕES: Anormalidades de circulação cerebral podem ter relação com prejuízos cognitivos relatados em populações de dependentes de cocaína. Embora déficits de perfusão cerebral associados ao uso de cocaína possam ser irreversíveis, têm surgido relatos na literatura de tratamentos para essas anormalidades de fluxo sangüíneo. Alterações de fluxo sangüíneo cerebral associadas à dependência de cocaína ocorrem mesmo na ausência de abuso ou dependência de opióides.INTRODUCTION: In the last years, there have been reports of abnormalities in brain blood flow of cocaine abusers, detected by single photon computed

  15. A Conversation with Lee Shulman--Signature Pedagogies for Teacher Education: Defining Our Practices and Rethinking Our Preparation

    Science.gov (United States)

    Falk, Beverly

    2006-01-01

    Lee S. Shulman is the President of The Carnegie Foundation for the Advancement of Teaching, a foundation whose mission is "to do and perform all things necessary to encourage, uphold and dignify the profession of teaching." Prior to assuming his role at Carnegie, Shulman was the Charles E. Ducommun Professor of Education at Stanford…

  16. 76 FR 79228 - Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy...

    Science.gov (United States)

    2011-12-21

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy Carolinas, LLC AGENCY: Nuclear Regulatory Commission. ACTION: Draft environmental impact statement; public...

  17. Q & A with Ed Tech Leaders: Interview with Curtis J. Bonk, Mimi Miyoung Lee, Thomas C. Reeves, & Thomas H. Reynolds

    Science.gov (United States)

    Viner, Mark; Gardner, Ellen; Shaughnessy, Michael F.

    2016-01-01

    Curtis J. Bonk, is Professor of Instructional Systems Technology at Indiana University and President of CourseShare. Mimi Miyoung Lee is Associate Professor in the Department of Curriculum and instruction at the University of Houston. Thomas C. Reeves is Professor Emeritus of Learning, Design, and Technology at the University of Georgia. Thomas H.…

  18. General Robert E. Lee (1807-70) and Philanthropist George Peabody (1795-1869) at White Sulphur Springs, West Virginia, July 23-Aug. 30, 1869.

    Science.gov (United States)

    Parker, Franklin; Parker, Betty J.

    This paper discusses the chance meeting at White Sulphur Springs (West Virginia) of two important public figures, Robert E. Lee and George Peabody, whose rare encounter marked a symbolic turn from Civil War bitterness toward reconciliation and the lifting power of education. The paper presents an overview of Lee's life and professional and…

  19. Blood constituents of holstein cows fed with corn or elephant-grass silages / Constituintes sangüíneos de vacas da raça holandesa alimentadas com silagens de milho ou de capim-elefante

    Directory of Open Access Journals (Sweden)

    Valter Harry Bumbieris Júnior

    2010-07-01

    Full Text Available The objective of this work was to evaluate the effects of corn (Zea mays L. silage and elephant-grass (Pennisetum purpureum Schum silage on the nutrition of cows during lactation, over some of the blood constituents (glucose, triglycerides and urea. The treatments were three silages (corn silage, elephant-grass silage with bacterial inoculating, elephant-grass silage with enzyme-bacterial inoculating. Nine Holstein cows, with a medium weight of 520 kg, were distributed in experimental delineation of simultaneous triple Latin square. The blood glucose rates were considered normal, independents of the silage used. Concerning the triglicerides levels, it was verified that they are below normal to the different silages. One of the reasons would be the low fat level on the diet. The blood levels of urea observed on the three treatments are considered normal. There was not significant difference among the different kinds of silage in relation to the blood levels of urea, glucose and triglycerides.O objetivo deste trabalho foi avaliar os efeitos do fornecimento de silagem de milho (Zea mays L. e silagem de capim-elefante (Pennisetum purpureum Schum na alimentação de vacas em lactação, sobre alguns dos constituintes sangüíneos (glicose, triglicerídeos e uréia. Os tratamentos foram três silagens (silagem de milho, silagem de capim-elefante com inoculante bacteriano, silagem de capim-elefante com inoculante enzimo-bacteriano. Foram utilizadas nove vacas da raça holandesa, com peso médio de 520 kg, distribuídas em delineamento experimental de triplo quadrado latino simultâneo. As taxas de glicose sangüínea das vacas foram consideradas normais, independente do volumoso utilizado. Em relação aos níveis de triglicerídeos, verificou-se que estão abaixo do normal para os diferentes volumosos. Uma das razões seria o baixo nível de gordura na dieta. Os níveis sangüíneos de uréia observados nos três tratamentos são considerados normais

  20. Effect of Saccharomyces strains on the quality of red wines aged on lees.

    Science.gov (United States)

    Loira, I; Vejarano, R; Morata, A; Ricardo-da-Silva, J M; Laureano, O; González, M C; Suárez-Lepe, J A

    2013-08-15

    Ageing on lees involves ageing the wine in contact with yeast cells after fermentation. If combined with the addition of oak chips, it can soften the wood flavour and increase the aromatic complexity of wine. The aim of the present work is to optimise both ageing techniques through selection of an adequate Saccharomyces cerevisiae strain. The study lasted 6 months and content of polysaccharides, anthocyanins, proanthocyanidins, volatile compounds, colour parameters and sensory analysis, were periodically evaluated. Among the strains tested, G37 showed the highest release of polysaccharides (24.4±5.5 mg l(-1)). Vanillin, syringaldehyde and furfuryl alcohol increased with ageing time in 7VA2 treatment. The wine aged with CTPL14 strain presented fewer monomeric and oligomeric proanthocyanidins (12.4±0.6 and 83.4±8.3 mg l(-1), respectively), and showed the lowest astringency and bitterness sensations. Results show an improvement in the sensory profile of the red wine aged with a combination of these two techniques. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Lee-Carter state space modeling: Application to the Malaysia mortality data

    Science.gov (United States)

    Zakiyatussariroh, W. H. Wan; Said, Z. Mohammad; Norazan, M. R.

    2014-06-01

    This article presents an approach that formalizes the Lee-Carter (LC) model as a state space model. Maximum likelihood through Expectation-Maximum (EM) algorithm was used to estimate the model. The methodology is applied to Malaysia's total population mortality data. Malaysia's mortality data was modeled based on age specific death rates (ASDR) data from 1971-2009. The fitted ASDR are compared to the actual observed values. However, results from the comparison of the fitted and actual values between LC-SS model and the original LC model shows that the fitted values from the LC-SS model and original LC model are quite close. In addition, there is not much difference between the value of root mean squared error (RMSE) and Akaike information criteria (AIC) from both models. The LC-SS model estimated for this study can be extended for forecasting ASDR in Malaysia. Then, accuracy of the LC-SS compared to the original LC can be further examined by verifying the forecasting power using out-of-sample comparison.

  2. Structural modeling of age specific fertility curves in Peninsular Malaysia: An approach of Lee Carter method

    Science.gov (United States)

    Hanafiah, Hazlenah; Jemain, Abdul Aziz

    2013-11-01

    In recent years, the study of fertility has been getting a lot of attention among research abroad following fear of deterioration of fertility led by the rapid economy development. Hence, this study examines the feasibility of developing fertility forecasts based on age structure. Lee Carter model (1992) is applied in this study as it is an established and widely used model in analysing demographic aspects. A singular value decomposition approach is incorporated with an ARIMA model to estimate age specific fertility rates in Peninsular Malaysia over the period 1958-2007. Residual plots is used to measure the goodness of fit of the model. Fertility index forecast using random walk drift is then utilised to predict the future age specific fertility. Results indicate that the proposed model provides a relatively good and reasonable data fitting. In addition, there is an apparent and continuous decline in age specific fertility curves in the next 10 years, particularly among mothers' in their early 20's and 40's. The study on the fertility is vital in order to maintain a balance between the population growth and the provision of facilities related resources.

  3. Hartree-Fock treatment of Fermi polarons using the Lee-Low-Pine transformation

    Science.gov (United States)

    Kain, Ben; Ling, Hong Y.

    2017-09-01

    We consider the Fermi polaron problem at zero temperature, where a single impurity interacts with noninteracting host fermions. We approach the problem starting with a Fröhlich-like Hamiltonian where the impurity is described with canonical position and momentum operators. We apply the Lee-Low-Pine (LLP) transformation to change the fermionic Fröhlich Hamiltonian into the fermionic LLP Hamiltonian, which describes a many-body system containing host fermions only. We adapt the self-consistent Hartree-Fock (HF) approach, first proposed by Edwards, to the fermionic LLP Hamiltonian in which a pair of host fermions with momenta k and k' interact with a potential proportional to k .k' . We apply the HF theory, which has the advantage of not restricting the number of particle-hole pairs, to repulsive Fermi polarons in one dimension. When the impurity and host fermion masses are equal our variational ansatz, where HF orbitals are expanded in terms of free-particle states, produces results in excellent agreement with McGuire's exact analytical results based on the Bethe ansatz. This work raises the prospect of using the HF ansatz and its time-dependent generalization as building blocks for developing all-coupling theories for both equilibrium and nonequilibrium Fermi polarons in higher dimensions.

  4. Nobelist TD LEE Scientist Cooperation Network and Scientist Innovation Ability Model

    Directory of Open Access Journals (Sweden)

    Jin-Qing Fang

    2013-01-01

    Full Text Available Nobelist TD Lee scientist cooperation network (TDLSCN and their innovation ability are studied. It is found that the TDLSCN not only has the common topological properties both of scale-free and small-world for a general scientist cooperation networks, but also appears the creation multiple-peak phenomenon for number of published paper with year evolution, which become Nobelist TD Lee’s significant mark distinguished from other scientists. This new phenomenon has not been revealed in the scientist cooperation networks before. To demonstrate and explain this new finding, we propose a theoretical model for a nature scientist and his/her team innovation ability. The theoretical results are consistent with the empirical studies very well. This research demonstrates that the model has a certain universality and can be extended to estimate innovation ability for any nature scientist and his/her team. It is a better method for evaluating scientist innovation ability and his/her team for the academic profession and is of application potential.

  5. The spirit of St Louis: the contributions of Lee N. Robins to North American psychiatric epidemiology.

    Science.gov (United States)

    Campbell, Nancy D

    2014-08-01

    This article takes up the history of North American psychiatric epidemiology with reference to production of knowledge concerning sociopathic or antisocial personality disorder and drug dependence, abuse, and/or addiction. These overlapping arenas provide a microcosm within which to explore the larger shift of postwar psychiatric epidemiology from community studies based on psychological scales to studies based on specific diagnostic criteria. This paper places the figure of sociologist Lee Nelken Robins within the context of the Department of Psychiatry in the School of Medicine at Washington University in St Louis, Missouri. The St Louis research group--to which Robins was both marginal and central--developed the basis for specific diagnostic criteria and was joined by Robert Spitzer, Jean Endicott and other architects of DSM-III in reorienting American psychiatry towards medical, biological and epidemiological models. Robins was a key linchpin working at the nexus of the psychiatric epidemiological and sociological drug addiction research networks. This article situates her work within the broader set of societal and governmental transformations leading to the technologically sophisticated turn in American psychiatric epidemiology and research on the aetiology of drug abuse and mental health and illness. Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2013; all rights reserved.

  6. The other Higgses, at resonance, in the Lee-Wick extension of the Standard Model

    CERN Document Server

    Figy, Terrance

    2011-01-01

    Within the framework of the Lee Wick Standard Model (LWSM) we investigate Higgs pair production $gg \\to h_0 h_0$, $gg \\to h_0 \\tilde p_0$ and top pair production $gg \\to \\bar tt$ at the Large Hadron Collider (LHC), where the neutral particles from the Higgs sector ($h_0$, $\\tilde h_0$ and $\\tilde p_0$) appear as possible resonant intermediate states. We investigate the signal $gg \\to h_0 h_0 \\to \\bar b b \\gamma \\gamma$ and we find that the LW Higgs, depending on its mass-range, can be seen not long after the LHC upgrade in 2012. More precisely this happens when the new LW Higgs states are below the top pair threshold. In $gg \\to \\bar tt$ the LW states, due to the wrong-sign propagator and negative width, lead to a dip-peak structure instead of the usual peak-dip structure which gives a characteristic signal especially for low-lying LW Higgs states. We comment on the LWSM and the forward-backward asymmetry in view of the measurement at the TeVatron. Furthermore, we present a technique which reduces the hyperbo...

  7. Kuula ka neid / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2009-01-01

    Tutvustused : XXI Sajandi Orkester. Üheksa. Tallinn : XXISO, 2008. Illustraator. Minu keha. Tallinn : MTÜ ILL Produktsioon, 2008. Pastoraal. Helirännak põldudel ja heinamaadel. Tallinn : Eestimaa Looduse fond, 2008

  8. PIERRE BOURDIEU, SANG JURU DAMAI

    OpenAIRE

    Krisdinanto, Nanang

    2016-01-01

    Pierre Bourdieu built his theoretical orientation as a solution to what he saw as a false opposition between objectivism and subjectivism; to quote Bourdieu: “absurd opposition between individual and society”. Bourdieu offered a point of view that emphasizes on duality in the relationship between agent and structure, as an alternative to the previously existing dualistic views. Bourdieu refers to his theoretical orientation as genetic structuralism, constructivist structuralism or structurali...

  9. Kuula ka neid / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2009-01-01

    Heliplaaditutvustused: Bullfrog Brown with Steve Lury. KWAQ Records, 2009; Grupa Janke Randalu. Live. [Saksamaa] : Jazz'n'Arts, 2008; Paha Polly. Ei jäägi üle muud... [Tartu] : Forward, 2008. Uutest heliplaatidest

  10. Associação entre marcadores de grupos sangüíneos e produção à primeira lactação em bovinos da raça Gir Leiteiro

    Directory of Open Access Journals (Sweden)

    Conceição R.O.

    2000-01-01

    Full Text Available Foram analisados 138 resultados de tipagem sangüínea de animais da raça Gir Leiteiro, pertencentes a uma população fechada submetida a acasalamentos preferenciais por aproximadamente 30 anos. Estudou-se a associação entre os sistemas B, F, J, L e Z de grupos sangüíneos e a produção de leite à primeira lactação. Os resultados mostraram diferença significativa (P<0,001 na produção de leite das primíparas que possuem o fator Z, 3634,43kg, em relação as que não apresentaram o mesmo fator, 3074,62kg. Para o sistema B, por meio de contraste de médias, verificou-se que houve diferença significativa (P<0,05 entre animais com o fenogrupo I1O1Y2A?B?E?3(J?K?P?Q? em homozigose, 4202,86kg, e aqueles com os fenogrupos B(PQTE?3G?P?/I1O1Y2A?B?E?3(J?K?P?Q?, 3493,33kg, e BQTA?B?I?(P?/I1O1Y2A?B?E?3(J?K?P?Q?, 3630,36kg.

  11. Extracorporeal irradiation of calves blood. Effects on: the lymphocytes, the blood-platelet function, seric proteins, and fibrinogen; Irradiation extracorporelle du sang de veau effets sur: les lymphocytes, la fonction plaquettaire, les proteines seriques et le fibrinogene

    Energy Technology Data Exchange (ETDEWEB)

    Hollard, D.; Suscillon, M.; Benabid, Y.; Concord, E.; Ivanoff, M.; Laurent, M.; Rambaud, F. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    The present paper reports the results obtained after extracorporeal irradiation of circulating blood of calves. Animals are divided in 3 groups as follows: - control animals: blood circulation without irradiation; - calves which received 40000 rads during 24 hours of continuous irradiation; - calves which received the same dose, during a period of 5 days (5 hours every day). The more interesting results are: - the early lymphopenia which persists for 7 or 8 weeks and may be in relationship with the change of immunoglobulins; - a constant hyperfibrinemia (12 g/l) never reported, as far as we know, by authors using I.E.C. Several hypothesis are advanced to explain this phenomenon. (authors) [French] Ce travail presente l'ensemble des resultats hematologiques obtenus apres irradiation extracorporelle du sang de veaux repartis en 3 series: - veaux temoins: circulation du sang sans irradiation - veaux soumis a une irradiation continue dose globale integree de 40000 rads en 24 heures; - veaux ayant recu la meme dose globale en irradiation fractionnee repartie sur 5 jours (5 heures par jour). Les resultats les plus marquants sont d'une part une lymphopenie precoce se prolongeant durant 7 a 8 semaines et qui pourrait etre reliee aux modifications observees sur les immunoglobulines. D'autre part une hyperfibrinemie (12 g/l) constante, apparemment jamais signalee par d'autres auteurs utilisant l'I.E.C. Plusieurs hypotheses explicatives de ce phenomene sont exposees et sont a l'etude. (auteurs)

  12. Details of the general numerical solutions of the Friedberg-Lee soliton model for ground and exited states

    International Nuclear Information System (INIS)

    Koeppel, T.; Harvey, M.

    1984-06-01

    A new numerical method is applied to solving the equations of motion of the Friedberg-Lee Soliton model for both ground and spherically symmetric excited states. General results have been obtained over a wide range of parameters. Critical coupling constants and critical particle numbers have been determined below which soliton solutions cease to exist. The static properties of the proton are considered to show that as presently formulated the model fails to fit all experimental data for any set of parameters

  13. Diurnal variability of inner-shelf circulation in the lee of a cape under upwelling conditions

    Science.gov (United States)

    Lamas, L.; Peliz, A.; Dias, J.; Oliveira, P. B.; Angélico, M. M.; Castro, J. J.; Fernandes, J. N.; Trindade, A.; Cruz, T.

    2017-07-01

    The nearshore circulation in the lee of a cape under upwelling conditions was studied using in-situ data from 3 consecutive summers (2006-2008). Focus was given to a period between 20 July and 04 August 2006 to study the diurnal variability of the cross-shelf circulation. This period was chosen because it had a steady upwelling-favourable wind condition modulated by a diurnal cycle much similar to sea breeze. The daily variability of the observed cross-shelf circulation consisted of three distinct periods: a morning period with a 3-layer vertical structure with onshore velocities at mid-depth, a mid-day period where the flow is reversed and has a 2-layer structure with onshore velocities at the surface and offshore flow below, and, lastly, in the evening, a 2-layer period with intensified offshore velocities at the surface and onshore flow at the bottom. The observed cross-shelf circulation showed a peculiar vertical shape and diurnal variability different from several other systems described in literature. We hypothesize that the flow reversal of the cross-shelf circulation results as a response to the rapid change of the wind magnitude and direction at mid-day with the presence of the cape north of the mooring site influencing this response. A numerical modelling experiment exclusively forced by winds simulated successfully most of the circulation at the ADCP site, especially the mid-day reversal and the evening's upwelling-type structure. This supports the hypothesis that the cross-shelf circulation at diurnal timescales is mostly wind-driven. By analysing the 3D circulation in the vicinity of Cape Sines we came to the conclusion that the diurnal variability of the wind and the flow interaction with topography are responsible for the circulation variability at the ADCP site, though only a small region in the south of the cape showed a similar diurnal variability. The fact that the wind diurnally undergoes relaxation and intensification strongly affects the

  14. "Embodiment as procedures: Physical cleansing changes goal priming effects": Correction to Dong and Lee (2017).

    Science.gov (United States)

    2017-06-01

    Reports an error in "Embodiment as procedures: Physical cleansing changes goal priming effects" by Ping Dong and Spike W. S. Lee ( Journal of Experimental Psychology: General , 2017[Apr], Vol 146[4], 592-605). In the article, the following F-value and p-values in the Results section of Experiment 3 were set incorrectly: The p -value p =.925 should be p =.922. The F - and p -values F (1, 201)=.011, p =.916 should be F (1, 201) .014, p = .906. (The following abstract of the original article appeared in record 2017-14922-010.) Physical cleansing reduces the influence of numerous psychological experiences, such as guilt from immoral behavior, dissonance from free choice, and good/bad luck from winning/losing. How do these domain-general effects occur? We propose an integrative account of cleansing as an embodied procedure of psychological separation. By separating physical traces from a physical target object (e.g., detaching dirt from hands), cleansing serves as the embodied grounding for the separation of psychological traces from a psychological target object (e.g., dissociating prior experience from the present self). This account predicts that cleansing reduces the accessibility of psychological traces and their consequences for judgments and behaviors. Testing these in the context of goal priming, we find that wiping one's hands (vs. not) decreases the mental accessibility (Experiment 1), behavioral expression (Experiment 2), and judged importance (Experiments 3-4) of previously primed goals (e.g., achievement, saving, fitness). But if a goal is primed after cleansing, its importance gets amplified instead (Experiment 3). Based on the logic of moderation-of-process, an alternative manipulation that psychologically separates a primed goal from the present self produces the same effects, but critically, the effects vanish once people wipe their hands clean (Experiment 4), consistent with the notion that cleansing functions as an embodied procedure of psychological

  15. Análise da coagulação sangüínea em pacientes submetidas à hiperestimulação ovariana para fertilização in vitro

    Directory of Open Access Journals (Sweden)

    MICHELON JOÃO

    2002-01-01

    Full Text Available OBJETIVO: Identificar alterações na coagulação sangüínea em mulheres submetidas à fertilização in vitro (FIV. MÉTODOS: Trata-se de um estudo prospectivo onde foram incluídas 15 pacientes submetidas à FIV. No período pré-ovulatório imediato, do ciclo menstrual precedente à FIV, foi coletada amostra sangüínea para coagulograma, com dosagem de Estradiol, Hemograma, Fibrinogênio, Tempo de Protrombina, Tempo de Tromboplastina Parcial Ativada, Tempo de Coagulação e Plaquetas. Durante a hiperestimulação ovariana para FIV, nova amostra para coagulograma foi coletada no dia da aplicação da Gonadotrofina Coriônica Humana. Os dados referentes à análise das duas amostras foram avaliados usando teste estatístico Paired T-Test. RESULTADOS: O estudo comparativo das médias das amostras identificou aumento significativo nos níveis de fibrinogênio, 304,9 pg/ml na primeira amostra e 383,1 pg/ml na segunda (p=0,01, já os níveis de hematócrito tiveram um decréscimo significativo, com valores de 40,5% e 38,4%, respectivamente (p=0,0001. As demais provas de coagulação não apresentaram diferença significativa. As médias do estradiol foram significativamente diferentes, sendo 167pg/ml na primeira amostra e 1435pg/ml na segunda (p=0,0001. CONCLUSÕES: Os Dados refletem uma tendência a um estado de hipercoagüabilidade sangüínea, o que é esperado nas situações de hiperestrogenismo. Apesar da significância estatística nos níveis de fibrinogênio e hematócrito, esses resultados têm pouca expressão clínica, visto que os valores máximos das duas amostras permaneceram dentro dos limites da normalidade. A pesquisa sugere que, apesar do grande aumento nos níveis de estradiol e mudanças nas provas de coagulação, os programas de FIV mostram-se seguros quanto aos riscos tromboembólicos.

  16. Influência da terapia com espironolactona sobre níveis sangüíneos de tiamina em pacientes com insuficiência cardíaca

    OpenAIRE

    Rocha,Ricardo Mourilhe; Silva,Guilherme Vianna e; Albuquerque,Denilson Campos de; Tura,Bernardo Rangel; Albanesi Filho,Francisco Manes

    2008-01-01

    FUNDAMENTO: Estudos do manejo não-farmacológico da insuficiência cardíaca (IC) têm sido muito escassos. A importância de micronutrientes como tiamina há muito é conhecida, uma vez que sua deficiência está associada com o desenvolvimento de IC de alto débito. OBJETIVO: Nós estudamos a relação entre adicionar à inibição da ECA uma supressão adicional da aldosterona com espironolactona e níveis sangüíneos de tiamina (pmol/ml). MÉTODOS: Um total de 22 pacientes (pc) com IC (classes III/IV da NYHA...

  17. Blood cell attachment to root surfaces treated with EDTA gel Adesão de células sangüíneas a superfícies radiculares tratadas com gel de EDTA

    Directory of Open Access Journals (Sweden)

    Fábio Renato Manzolli Leite

    2005-06-01

    Full Text Available Root debridement generates a smear layer which contains microorganisms and toxins that could interfere in periodontal healing. For this reason, different substances have been used to remove it and to expose collagen fibers at the tooth surface. Blood element adhesion to demineralized roots and clot stabilization by collagen fibers are extremely important for the success of periodontal surgery. The aim of this study was to evaluate the different patterns of blood element adsorption and adhesion to root surfaces only irrigated with distilled water and after application of a manipulated or an industrialized EDTA gel. Thirty samples were planed, equally divided into three groups and treated with distilled water (control, a manipulated EDTA gel or an industrialized one. Immediately after, samples were exposed to fresh blood and prepared for scanning electron microscopy. Untreated planed dentin presented the best results with blood cells entrapped in a thick web of fibrin. In the manipulated EDTA group, the web of fibrin was thick with sparse blood elements. The worst result was seen with the industrialized EDTA group, in which no blood elements could be seen. Statistical difference was obtained between control and industrialized EDTA groups. Surfaces only irrigated presented the most organized fibrin network and cell entrapment.A raspagem gera "smear layer", a qual contém microrganismos e toxinas que podem interferir no reparo periodontal. Por esse motivo, diferentes substâncias têm sido empregadas para remover esta camada e expor fibras colágenas da superfície dental. A adesão de elementos sangüíneos a superfícies radiculares desmineralizadas e a estabilização do colágeno pelas fibras colágenas são de extrema importância no sucesso da cirurgia periodontal. O objetivo deste estudo foi avaliar os diferentes padrões de adsorção e adesão de elementos sangüíneos a superfícies radiculares apenas irrigadas com água destilada e ap

  18. Interferência dos ácidos graxos ômega-3 nos lipídeos sangüíneos de ratos submetidos ao exercício de natação

    OpenAIRE

    Moritz, Bettina; Wazlawik, Elisabeth; Minatti, Jaqueline; Miranda, Rafaella Cristina Dimbarre de

    2008-01-01

    OBJETIVO: Investigar os efeitos da suplementação com ácidos graxos ômega-3, nas doses de 0,5 e 1,0g/kg/dia, nos lipídeos sangüíneos de ratos submetidos ou não ao protocolo do nado. MÉTODOS: Ratos Wistar foram divididos em grupos: controle, controle+nado, ácidos graxos ômega-3 e ácidos graxos ômega-3+nado. Os ácidos graxos ômega-3 e ácidos graxos ômega-3+nado receberam suplementação; os demais receberam água por gavagem. Os controle+nado e ácidos graxos ômega-3+nado foram submetidos ao exercíc...

  19. Amino acid residues in the Ler protein critical for derepression of the LEE5 promoter in enteropathogenic E. coli.

    Science.gov (United States)

    Choi, Su-Mi; Jeong, Jae-Ho; Choy, Hyon E; Shin, Minsang

    2016-08-01

    Enteropathogenic E. coli causes attaching and effacing (A/E) intestinal lesions. The genes involved in the formation of A/E lesions are encoded within a chromosomal island comprising of five major operons, LEE1-5. The global regulator H-NS represses the expression of these operons. Ler, a H-NS homologue, counteracts the H-NS-mediated repression. Using a novel genetic approach, we identified the amino acid residues in Ler that are involved in the interaction with H-NS: I20 and L23 in the C-terminal portion of α-helix 3, and I42 in the following unstructured linker region.

  20. A linear model for rotors produced by trapped lee waves with a simple representation of boundary layer friction

    Science.gov (United States)

    Teixeira, Miguel A. C.

    2017-04-01

    A linear model is used to diagnose the onset of rotors in flow over 2D ridges, for atmospheres that are neutrally stratified near the surface and stably stratified aloft, with a sharp temperature inversion in between, where trapped lee waves may propagate. This is achieved by coupling an inviscid two-layer mountain-wave model with a bulk boundary-layer model. The full model shows some ability to detect flow stagnation as a function of key input parameters, such as the Froude number and the height of the inversion, by comparison with results from numerical simulations and laboratory experiments carried out by previous authors. The effect of a boundary layer is essential to correctly predict flow stagnation, as the inviscid version of the model severely overestimates the dimensionless critical mountain height necessary for stagnation to occur. An improved model that includes only the effects of mean flow deceleration and amplification of the velocity perturbation within the boundary layer predicts flow stagnation much better in the most non-hydrostatic cases treated here, where waves appear to be directly forced by the orography. However, in the most hydrostatic case, only the full model, taking into account the feedback of the boundary layer on the inviscid flow, satisfactorily predicts flow stagnation, although the corresponding stagnation condition is unable to discriminate between rotors and hydraulic jumps. This is due to the fact that the trapped lee waves associated with the rotors are not forced directly by the orography in this case, but rather seem to be generated indirectly by nonlinear processes. This mechanism is, to a certain extent, mimicked by the modified surface boundary condition adopted in the full model, where an "effective orography" that differs from the real one forces the trapped lee waves. Versions of the model not including this feedback severely underestimate the amplitude of the trapped lee waves in the most hydrostatic case, partly

  1. Okhee Lee, Cory A. Buxton, James A. Banks (ed.), Diversity and equity in science education: research, policy, and practice

    Science.gov (United States)

    Bannier, Betsy J.

    2015-06-01

    Highly relevant for academic study among K-12 educators and the higher education faculty who train pre-service teachers, Diversity and equity in science education highlights three interrelated issues impacting science education in the United States. First, complicated dynamics related to the large and increasing population of English language learning (ELL) students are discussed. Second, the realities of standardized test scores are comparatively explored, both within and beyond the United States. Third, the politics of accountability in education are vigorously discussed. Okhee Lee and Cory A. Buxton weave through the contexts of politics, education, science, and culture to expand existing discourse about how to best educate our nation's children.

  2. Esse tal de Roque Enrow! : a trajetória de Rita Lee de outsider ao mainstream (1967-1985)

    OpenAIRE

    Gohl, Jeffferson William

    2014-01-01

    O presente trabalho acompanhou parte da trajetória da artista Rita Lee Jones no período entre 1967 até 1985. Valendo-se de fontes, discográficas, documentos audiovisuais, documentos de arquivo e discursos produzidos pela imprensa, procurou documentar desde o momento contracultural em que ela participou do grupo Os Mutantes junto aos movimentos da Tropicália, até seu momento de reconhecimento de maturidade artística que ocorre concomitante ao término do Regime Militar autoritário no Brasil. ...

  3. Evaluating the performance of the Lee-Carter method and its variants in modelling and forecasting Malaysian mortality

    Science.gov (United States)

    Zakiyatussariroh, W. H. Wan; Said, Z. Mohammad; Norazan, M. R.

    2014-12-01

    This study investigated the performance of the Lee-Carter (LC) method and it variants in modeling and forecasting Malaysia mortality. These include the original LC, the Lee-Miller (LM) variant and the Booth-Maindonald-Smith (BMS) variant. These methods were evaluated using Malaysia's mortality data which was measured based on age specific death rates (ASDR) for 1971 to 2009 for overall population while those for 1980-2009 were used in separate models for male and female population. The performance of the variants has been examined in term of the goodness of fit of the models and forecasting accuracy. Comparison was made based on several criteria namely, mean square error (MSE), root mean square error (RMSE), mean absolute deviation (MAD) and mean absolute percentage error (MAPE). The results indicate that BMS method was outperformed in in-sample fitting for overall population and when the models were fitted separately for male and female population. However, in the case of out-sample forecast accuracy, BMS method only best when the data were fitted to overall population. When the data were fitted separately for male and female, LCnone performed better for male population and LM method is good for female population.

  4. Analyses and optimization of Lee propagation model for LoRa 868 MHz network deployments in urban areas

    Directory of Open Access Journals (Sweden)

    Dobrilović Dalibor

    2017-01-01

    Full Text Available In the recent period, fast ICT expansion and rapid appearance of new technologies raised the importance of fast and accurate planning and deployment of emerging communication technologies, especially wireless ones. In this paper is analyzed possible usage of Lee propagation model for planning, design and management of networks based on LoRa 868MHz technology. LoRa is wireless technology which can be deployed in various Internet of Things and Smart City scenarios in urban areas. The analyses are based on comparison of field measurements with model calculations. Besides the analyses of Lee propagation model usability, the possible optimization of the model is discussed as well. The research results can be used for accurate design, planning and for preparation of high-performance wireless resource management of various Internet of Things and Smart City applications in urban areas based on LoRa or similar wireless technology. The equipment used for measurements is based on open-source hardware.

  5. Tentative identification of polar and mid-polar compounds in extracts from wine lees by liquid chromatography-tandem mass spectrometry in high-resolution mode.

    Science.gov (United States)

    Delgado de la Torre, M P; Priego-Capote, F; Luque de Castro, M D

    2015-06-01

    Sustainable agriculture has a pending goal in the revalorization of agrofood residues. Wine lees are an abundant residue in the oenological industry. This residue, so far, has been used to obtain tartaric acid or pigments but not for being qualitatively characterized as a source of polar and mid-polar compounds such as flavonoids, phenols and essential amino acids. Lees extracts from 11 Spanish wineries have been analyzed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) in high resolution mode. The high-resolution power of LC-MS/MS has led to the tentative identification of the most representative compounds present in wine lees, comprising primary amino acids, anthocyans, flavanols, flavonols, flavones and non-flavonoid phenolic compounds, among others. Attending to the profile and content of polar and mid-polar compounds in wine lees, this study underlines the potential of wine lees as an exploitable source to isolate interesting compounds. Copyright © 2015 John Wiley & Sons, Ltd.

  6. Grey relational analysis for evaluating the effects of different rates of wine lees-derived biochar application on a plant-soil system with multi-metal contamination.

    Science.gov (United States)

    Xu, Min; Zhu, Qihong; Wu, Jun; He, Yan; Yang, Gang; Zhang, Xiaohong; Li, Li; Yu, Xiaoyu; Peng, Hong; Wang, Lilin

    2018-03-01

    In this study, grey relational analysis (GRA) was used to investigate the effects of different application rates of wine lees-derived biochar on a plant-soil system with multi-metal contamination. A pot experiment was conducted to determine rice growth in multi-metal-contaminated soil amended with samples of wine lees-derived biochar, and 47 indicators (including soil properties, microbial activity, and plant physiology) were selected as evaluation indexes to assess the plant-soil system. The results indicated that higher wine lees-derived biochar application rates (2% W/W) were favorable for soil fertility, the bioconcentration factor (BF), and the mobility factor (MF, %) (with the exception of Cr, Zn, and Hg), but an application of 1% produced the highest plant growth, enzymatic activities, and bacterial diversity. The richness of the bacterial communities was reduced in the soil amended with the wine lees-derived biochar. According to the GRA assessment, the 1% application rate of wine lees-derived biochar was more suitable for restoring the holistic plant-soil system than were the application rates of 0, 0.5, and 2% (W/W). Furthermore, this study shows that GRA is a useful method for evaluating plant-soil systems.

  7. NsrR, GadE, and GadX interplay in repressing expression of the Escherichia coli O157:H7 LEE pathogenicity island in response to nitric oxide.

    Directory of Open Access Journals (Sweden)

    Priscilla Branchu

    2014-01-01

    Full Text Available Expression of genes of the locus of enterocyte effacement (LEE is essential for adherence of enterohemorrhagic Escherichia coli (EHEC to intestinal epithelial cells. Gut factors that may modulate LEE gene expression may therefore influence the outcome of the infection. Because nitric oxide (NO is a critical effector of the intestinal immune response that may induce transcriptional regulation in enterobacteria, we investigated its influence on LEE expression in EHEC O157:H7. We demonstrate that NO inhibits the expression of genes belonging to LEE1, LEE4, and LEE5 operons, and that the NO sensor nitrite-sensitive repressor (NsrR is a positive regulator of these operons by interacting directly with the RNA polymerase complex. In the presence of NO, NsrR detaches from the LEE1/4/5 promoter regions and does not activate transcription. In parallel, two regulators of the acid resistance pathway, GadE and GadX, are induced by NO through an indirect NsrR-dependent mechanism. In this context, we show that the NO-dependent LEE1 down-regulation is due to absence of NsrR-mediated activation and to the repressor effect of GadX. Moreover, the inhibition of expression of LEE4 and LEE5 by NO is due to loss of NsrR-mediated activation, to LEE1 down-regulation and to GadE up-regulation. Lastly, we establish that chemical or cellular sources of NO inhibit the adherence of EHEC to human intestinal epithelial cells. These results highlight the critical effect of NsrR in the regulation of the LEE pathogenicity island and the potential role of NO in the limitation of colonization by EHEC.

  8. Brown trout in the Lees Ferry reach of the Colorado River—Evaluation of causal hypotheses and potential interventions

    Science.gov (United States)

    Runge, Michael C.; Yackulic, Charles B.; Bair, Lucas S.; Kennedy, Theodore A.; Valdez, Richard A.; Ellsworth, Craig; Kershner, Jeffrey L.; Rogers, R. Scott; Trammell, Melissa A.; Young, Kirk L.

    2018-04-17

    Over the period 2014–2016, the number of nonnative brown trout (Salmo trutta) captured during routine monitoring in the Lees Ferry reach of the Colorado River, downstream of Glen Canyon Dam, began increasing. Management agencies and stakeholders have questioned whether the increase in brown trout in the Lees Ferry reach represents a threat to the endangered humpback chub (Gila cypha), to the rainbow trout (Oncorhynchus mykiss) sport fishery, or to other resources of concern. In this report, we evaluate the evidence for the expansion of brown trout in the Lees Ferry reach, consider a range of causal hypotheses for this expansion, examine the likely efficacy of several potential management interventions to reduce brown trout, and analyze the effects of those interventions on other resources of concern.The brown trout population at Lees Ferry historically consisted of a small number of large fish supported by low levels of immigration from downstream reaches. This population is now showing signs of sustained successful reproduction and is on the cusp of recruiting locally hatched fish into the spawning class, based on analysis with a new integrated population model. The proximate causes of this change in status are a large pulse of immigration in the fall of 2014 and higher reproductive rates in 2015–2017. The ultimate causes of this change are not clear. The pulse of immigrants from downstream reaches in fall 2014 may have been induced by three sequential high-flow releases from the dam in November of 2012–2014, but may also have been the result of a unique set of circumstances unrelated to dam operations. The increase in reproduction may have been the result of any number of changes, including an Allee effect, warmer water temperatures, a decrease in competition from rainbow trout, or fall high-flow releases. Correlations over space and time among predictor variables do not allow us to make a clear inference about the cause of the changes. Under a null causal

  9. The role of upper tropospheric jet streaks and lee-side cyclogenesis in the development of low level jets in the great plains

    Science.gov (United States)

    Uccellini, L. W.

    1980-01-01

    A review of 15 cases of low level jets (LLJ) which developed in the Great Plains is presented. For 12 out of the 15 cases, a systematic upper level flow pattern was isolated which includes the existence of a trough over the southwest United States and the propagation of upper level jet streaks from the Rocky Mountains toward the Great Plains. This flow pattern is responsible for lee side cyclogenesis or lee side troughing that produces the pressure gradients needed for the development of the LLJ. For the other three cases, a blocking ridge existed over the Great Plains and the upper level flow is relatively weak. It is during these situations that the classic, diurnal oscillating LLJ was observed. A more detailed review of four cases indicates that the subsynoptic scale adjustments associated with the upper level jet streak's forcing of lee side cyclogenesis could be an important factor in the development of LLJ's in the Great Plains.

  10. Centralização do Fluxo Sangüíneo Fetal Diagnosticado pela Dopplervelocimetria em Cores: Resultados Perinatais Brain-sparing Effect Detected by Color Doppler: Perinatal Outcome

    Directory of Open Access Journals (Sweden)

    Cleide Mara Mazzotti Oliveira Franzin

    2001-12-01

    Full Text Available Objetivos: avaliar os resultados perinatais do exame de dopplervelocimetria alterado com centralização de fluxo sangüíneo fetal. Metodologia: foram analisados 32 casos de centralização de fluxo sangüíneo fetal diagnosticados no Centro de Atenção Integral à Saúde da Mulher da Universidade Estadual de Campinas. O diagnóstico de centralização foi confirmado quando a relação entre o índice de pulsatilidade da artéria cerebral média fetal (IPACM e o índice de pulsatilidade da artéria umbilical (IPAU era menor que a unidade (IPACM/IPAU menor que 1. Detectou-se fluxo arterial usando equipamento ultra-sonográfico equipado com mapeamento em cores, marca Toshiba, modelo SSH-140A. Resultados: houve necessidade de cuidados intensivos em 26 fetos (89,6%. O número de dias de internação em unidade de terapia intensiva variou de 1 a 83, com média de 22 dias. A ocorrência de óbito fetal foi de 3/32 (9,4% e de óbito perinatal de 9/29 (31%. Considerando-se a idade gestacional avaliada pelo método de Capurro, a incidência de nascimento de fetos com menos de 36 semanas foi de 21/32 (65,6%. Crescimento intra-uterino restrito ocorreu em 71,8% dos fetos e hipoglicemia em 44,8%. Conclusão: a centralização de fluxo sangüíneo é um marcador de situação danosa ao bem-estar fetal e seu estudo será de grande valia na orientação da conduta obstétrica.Purpose: evaluation of perinatal outcome of brain-sparing effect detected by color Doppler. Methods: brain-sparing effect was detected in 32 fetuses at the Ultrasound Service of the Center for Integral Attention to Women's Health at Campinas State University (UNICAMP. The diagnosis of brain-sparing effect was made when the ratio between middle cerebral artery and umbilical artery pulsatility indexes was below one (IPACM/IPAU <1. The measurement was obtained with color Doppler equipment Toshiba SSH-140A. Results: admission to neonatal intensive care unit (ICU was necessary in 26 fetuses

  11. Prevalência do grupo sangüíneo DEA 1 (subgrupos 1.1 e 1.2 em cães (Canis familiaris, Linnaeus, 1758 criados no Brasil

    Directory of Open Access Journals (Sweden)

    Adriana Alonso Novais

    1999-01-01

    Full Text Available Os cães possuem cinco grupos sangüíneos bem estabelecidos, compostos por sete determinantes antigênicos eritrocitários, os quais são denominados de "dog erythrocyte antigen" (DEA. O grupo DEA 1 (subgrupos 1.1, 1.2 e 1.3 tem sido considerado o mais importante no que se refere às transfusões de sangue. Isto ocorre porque esse grupo possui um alto potencial para estimulação antigênica e, dessa forma, pode estimular a produção de anticorpos se um receptor DEA 1 negativo receber uma transfusão de sangue DEA 1 positivo, levando a uma reação transfusional hemolítica em uma segunda transfusão com hemácias do tipo DEA 1. A freqüência de aparecimento do grupo DEA 1 é bem conhecida em outros países, porém, até então, não havia informações disponíveis sobre o referido grupo no Brasil. No presente estudo, objetivou-se avaliar a prevalência do grupo sangüíneo DEA 1 (subgrupos 1.1 e 1.2 em cães criados no Brasil. Para tanto, 150 cães de raças, sexos e idades diferentes, triados junto ao Hospital Veterinário da FCAV/UNESP, Campus de Jaboticabal, foram submetidos a tipagem sangüínea para o grupo DEA 1 (subgrupos 1.1 e 1.2 canino, utilizando-se reagentes adquiridos comercialmente junto ao Laboratório de Imunoematologia e Sorologia da Universidade de Michigan (EUA. Os resultados obtidos neste ensaio revelaram que a prevalência geral para o grupo DEA 1 é de 91,3%, consideradas as condições e características da população estudada, compreendendo 51,3% de cães do tipo DEA 1.1, 40% de cães do tipo DEA 1.2, e os 8,7% restantes sendo negativos para o referido grupo. A partir das prevalências encontradas, calculou-se que a probabilidade de um cão DEA 1 negativo receber sangue DEA 1.1, em uma primeira transfusão feita ao acaso, é de aproximadamente 4,5%. Sendo assim, este índice reflete um risco potencial para a sensibilização de um receptor DEA 1 negativo, o que deflagraria a produção de anticorpos. Posteriormente

  12. Book Review: Drexl, J., Lee, N. (2013). Pharmaceutical Innovation, Competition and Patent Law : A Trilateral Perspective. Edward Elgar Publishing

    DEFF Research Database (Denmark)

    Minssen, Timo

    2014-01-01

    aspects of “Pharmaceutical Innovation, Competition and Patent Law”. It provides valuable analyses of the fundamental challenges that the pharmaceutical sector encounters on both a global and regional level. The editors and authors have thus compiled an important publication that will provide stimulation......This is a review of the recent publication “Pharmaceutical Innovation, Competition and Patent Law – A Trilateral Perspective”, edited by Max Planck Director Josef Drexl and Finnish scholar Nari Lee (Edward Elgar 2013, 322 p., ISBN 978 0 85793 245 7). In summary, I conclude that the editors, who...... of recent developments that have such a substantial impact on a significant area of law and practice. But are there any flaws? Considering the numerous useful case law citations, as well as the wide scope of the book, it is a little unfortunate that the book does not contain a table of cases...

  13. Mass elevation and lee effects markedly lift the elevational distribution of ground beetles in the Himalaya-Tibet orogen.

    Science.gov (United States)

    Schmidt, Joachim; Böhner, Jürgen; Brandl, Roland; Opgenoorth, Lars

    2017-01-01

    Mass elevation and lee effects markedly influence snow lines and tree lines in high mountain systems. However, their impact on other phenomena or groups of organisms has not yet been quantified. Here we quantitatively studied their influence in the Himalaya-Tibet orogen on the distribution of ground beetles as model organisms, specifically whether the ground beetle distribution increases from the outer to the inner parts of the orogen, against latitudinal effects. We also tested whether July temperature and solar radiation are predictors of the beetle's elevational distribution ranges. Finally, we discussed the general importance of these effects for the distributional and evolutionary history of the biota of High Asia. We modelled spatially explicit estimates of variables characterizing temperature and solar radiation and correlated the variables with the respective lower elevational range of 118 species of ground beetles from 76 high-alpine locations. Both July temperature and solar radiation significantly positively correlated with the elevational ranges of high-alpine beetles. Against the latitudinal trend, the median elevation of the respective species distributions increased by 800 m from the Himalayan south face north to the Transhimalaya. Our results indicate that an increase in seasonal temperature due to mass elevation and lee effects substantially impact the regional distribution patterns of alpine ground beetles of the Himalaya-Tibet orogen and are likely to affect also other soil biota there and in mountain ranges worldwide. Since these effects must have changed during orogenesis, their potential impact must be considered when biogeographic scenarios based on geological models are derived. As this has not been the practice, we believe that large biases likely exist in many paleoecological and evolutionary studies dealing with the biota from the Himalaya-Tibet orogen and mountain ranges worldwide.

  14. Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat

    Science.gov (United States)

    Uwingabiye, Jean; Zahid, Hafidi; Unyendje, Loubet; Hadef, Rachid

    2016-01-01

    Le but de ce travail était de déterminer la prévalence du virus de l’immunodéficience humaine (VIH), du virus de l’hépatite B (VHB) et C (VHC) sur les dons du sang collectés au Centre de transfusion sanguine(CTS) de l’hôpital militaire d’instruction Mohammed V entre 2010 et 2012. Etude rétrospective menée auprès des donneurs de sang militaires âgés de 18 à 50 ans avec prédominance masculine (95%). L’entretien médical pré-don constitue la première barrière de sélection des sujets à risque. Le dépistage biologique était réalisé par technique immuno-enzymatique en milieu liquide utilisant des anticorps et/ou des antigènes. L’ELISA (enzyme linked immuno-sorbent assay) combiné de quatrième génération pour VHC et VIH a été utilisé. La confirmation a été faite en réalisant la même technique en double au CTS et au laboratoire de virologie. Dans notre série de 25661 échantillons testés, la prévalence du VHB était 3,97‰ (n=102), celle de VHC était 2,45 ‰ (n=63), celle de VIH était 0,15 ‰ (n=4). Un seul cas de coïnfection (0,039 ‰) par le VHB et VHC a été noté, aucune association entre VIH-VHB, VIH-VHC ou VHB, VHC et VIH n’a été enregistrée. Les taux faibles de séroprévalence des marqueurs viraux de notre étude montrent l’amélioration des mesures préventives en ce qui concerne la sélection des donneurs et des tests de dépistage. Cette prévalence constatée incite à maintenir l’utilisation du réactif combiné qui est la seule alternative à la biologie moléculaire pour les pays en voie de développement. PMID:28292147

  15. Témoignages de la génération post-génocide au Rwanda : transmission et quête dans Un papa de sang de Jean Hatzfeld

    Directory of Open Access Journals (Sweden)

    Valérie Dusaillant-Fernandes

    2017-12-01

    Full Text Available Après Dans le nu de la vie (2000, Une saison des machettes (2003, La stratégie des antilopes (2007 et Englebert des collines (2014, Hatzfeld s’efface le temps d’un nouvel ouvrage, Un papa de sang (2015, pour porter son attention sur les enfants de victimes et de bourreaux dépositaires d’une souffrance qui ne leur appartient pas directement. Issus de familles Hutu ou Tutsi, ces jeunes, âgés de 16 à 20 ans, ne peuvent assimiler complètement des événements qu’ils n’ont pas connus et doivent, par la force des choses, s’efforcer de vivre dans le sillage d’un passé qui renvoie à l’horreur. Pour mieux comprendre l’impact inter- et transgénérationnel du génocide de 1994, nous proposons d’examiner la prise de parole d’adolescents et de jeunes adultes à travers les témoignages recueillis par Jean Hatzfeld et retranscrits dans Un papa de sang. Comment ces adolescents et jeunes adultes ont-ils découvert leur l’histoire familiale et de quelle façon évoquent-ils cette percée des secrets et des tabous ? Comment perçoivent-ils leur identité dans un pays où les « directives gouvernementales excluent les mots "hutu" et "tutsi" du langage de la société rwandaise » (155 ? Quelles démarches entreprennent-ils pour découvrir la vérité sur le passé familial ? Comment expriment-ils leurs craintes ? Font-ils part de méthodes particulières pour obtempérer aux exigences du vivre-ensemble ? Quels sont les expressions ou les mots choisis pour décrire les émotions ressenties lors de la semaine de deuil national qui se tient annuellement du 7 au 14 avril ? À quoi aspirent ces jeunes qui fréquentent les cafés Internet et découvrent une vérité parfois cachée par les voisins ou leurs proches ? Autant de questions auxquelles notre article tente de répondre à travers l’analyse de l’ouvrage d’Hatzfeld.

  16. W3C director Tim Berners-Lee to be Knighted by Queen Elizabeth web inventor recognized for contributions to internet development

    CERN Document Server

    2003-01-01

    "Tim Berners-Lee, the inventor of the World Wide Web and director of the World Wide Web Consortium (W3C), will be made a Knight Commander, Order of the British Empire (KBE) by Queen Elizabeth" (1/2 page).

  17. The NAG Sensor NagC Regulates LEE Gene Expression and Contributes to Gut Colonization by Escherichia coli O157:H7

    Directory of Open Access Journals (Sweden)

    Josée Harel

    2017-04-01

    Full Text Available Enterohemorrhagic Escherichia coli (EHEC O157:H7 are human pathogens responsible for bloody diarrhea and renal failures. EHEC employ a type 3 secretion system to attach directly to the human colonic epithelium. This structure is encoded by the locus of enterocyte effacement (LEE whose expression is regulated in response to specific nutrients. In this study, we show that the mucin-derived sugars N-acetylglucosamine (NAG and N-acetylneuraminic acid (NANA inhibit EHEC adhesion to epithelial cells through down-regulation of LEE expression. The effect of NAG and NANA is dependent on NagC, a transcriptional repressor of the NAG catabolism in E. coli. We show that NagC is an activator of the LEE1 operon and a critical regulator for the colonization of mice intestine by EHEC. Finally, we demonstrate that NAG and NANA as well as the metabolic activity of Bacteroides thetaiotaomicron affect the in vivo fitness of EHEC in a NagC-dependent manner. This study highlights the role of NagC in coordinating metabolism and LEE expression in EHEC and in promoting EHEC colonization in vivo.

  18. The Effects of Input Enhancement on Grammar Learning and Comprehension: A Modified Replication of Lee (2007) with Eye-Movement Data

    Science.gov (United States)

    Winke, Paula M.

    2013-01-01

    In his 2007 study "Effects of Textual Enhancement and Topic Familiarity on Korean EFL Students' Reading Comprehension and Learning of Passive Form," Lee demonstrated that learners were better able to correct written sentences that contained incorrect English passive forms after exposure to texts flooded with enhanced (versus…

  19. A cross-sectional study of correlation of body image anxiety with social phobia and their association with depression in the adolescents from a rural area of Sangli district in India

    Directory of Open Access Journals (Sweden)

    Vivek Baliram Waghachavare

    2014-01-01

    Full Text Available Background: Prevailing socio-cultural influences lead females to desire a thin body and males a muscular body, especially in adolescents. This results in body image anxiety which may lead to social phobia. Together they can develop depression. The aim was to study the correlation of body image anxiety with social phobia and their association with depression, among adolescents. Methods: This was a cross-sectional study conducted in randomly selected colleges from a rural area of Sangli district Maharashtra, India. Stratified random sampling technique used with sample size 805. Pretested self-administered questionnaire used. Percentage, Chi-square test, binary logistic regression model was used to estimate odds ratio (OR and its 95% confidence intervals. Results: Of 997 study subjects body image anxiety, social phobia and depression were observed in 232 (23.3%, 193 (19.4% and 326 (32.7% participants, respectively. Binary logistic regression showed that body image anxiety (OR = 1.849 [1.22, 2.804]; P = 0.004 and social phobia (OR = 4.575 [2.952-7.09]; P < 0.001 were significant predictors for depression. Conclusions: Body image anxiety and social phobia are linked with the development of depression. This impresses the need for timely counseling and education among adolescents.

  20. A Cross-sectional Study of Correlation of Body Image Anxiety with Social Phobia and Their Association with Depression in the Adolescents from a Rural Area of Sangli District in India.

    Science.gov (United States)

    Waghachavare, Vivek Baliram; Quraishi, Sanjay R; Dhumale, Girish B; Gore, Alka D

    2014-12-01

    Prevailing socio-cultural influences lead females to desire a thin body and males a muscular body, especially in adolescents. This results in body image anxiety which may lead to social phobia. Together they can develop depression. The aim was to study the correlation of body image anxiety with social phobia and their association with depression, among adolescents. This was a cross-sectional study conducted in randomly selected colleges from a rural area of Sangli district Maharashtra, India. Stratified random sampling technique used with sample size 805. Pretested self-administered questionnaire used. Percentage, Chi-square test, binary logistic regression model was used to estimate odds ratio (OR) and its 95% confidence intervals. Of 997 study subjects body image anxiety, social phobia and depression were observed in 232 (23.3%), 193 (19.4%) and 326 (32.7%) participants, respectively. Binary logistic regression showed that body image anxiety (OR = 1.849 [1.22, 2.804]; P = 0.004) and social phobia (OR = 4.575 [2.952-7.09]; P depression. Body image anxiety and social phobia are linked with the development of depression. This impresses the need for timely counseling and education among adolescents.

  1. Attaching and effacing (A/E) lesion formation by enteropathogenic E. coli on human intestinal mucosa is dependent on non-LEE effectors.

    Science.gov (United States)

    Cepeda-Molero, Massiel; Berger, Cedric N; Walsham, Alistair D S; Ellis, Samuel J; Wemyss-Holden, Simon; Schüller, Stephanie; Frankel, Gad; Fernández, Luis Ángel

    2017-10-01

    Enteropathogenic E. coli (EPEC) is a human pathogen that causes acute and chronic pediatric diarrhea. The hallmark of EPEC infection is the formation of attaching and effacing (A/E) lesions in the intestinal epithelium. Formation of A/E lesions is mediated by genes located on the pathogenicity island locus of enterocyte effacement (LEE), which encode the adhesin intimin, a type III secretion system (T3SS) and six effectors, including the essential translocated intimin receptor (Tir). Seventeen additional effectors are encoded by genes located outside the LEE, in insertion elements and prophages. Here, using a stepwise approach, we generated an EPEC mutant lacking the entire effector genes (EPEC0) and intermediate mutants. We show that EPEC0 contains a functional T3SS. An EPEC mutant expressing intimin but lacking all the LEE effectors but Tir (EPEC1) was able to trigger robust actin polymerization in HeLa cells and mucin-producing intestinal LS174T cells. However, EPEC1 was unable to form A/E lesions on human intestinal in vitro organ cultures (IVOC). Screening the intermediate mutants for genes involved in A/E lesion formation on IVOC revealed that strains lacking non-LEE effector/s have a marginal ability to form A/E lesions. Furthermore, we found that Efa1/LifA proteins are important for A/E lesion formation efficiency in EPEC strains lacking multiple effectors. Taken together, these results demonstrate the intricate relationships between T3SS effectors and the essential role non-LEE effectors play in A/E lesion formation on mucosal surfaces.

  2. Attaching and effacing (A/E lesion formation by enteropathogenic E. coli on human intestinal mucosa is dependent on non-LEE effectors.

    Directory of Open Access Journals (Sweden)

    Massiel Cepeda-Molero

    2017-10-01

    Full Text Available Enteropathogenic E. coli (EPEC is a human pathogen that causes acute and chronic pediatric diarrhea. The hallmark of EPEC infection is the formation of attaching and effacing (A/E lesions in the intestinal epithelium. Formation of A/E lesions is mediated by genes located on the pathogenicity island locus of enterocyte effacement (LEE, which encode the adhesin intimin, a type III secretion system (T3SS and six effectors, including the essential translocated intimin receptor (Tir. Seventeen additional effectors are encoded by genes located outside the LEE, in insertion elements and prophages. Here, using a stepwise approach, we generated an EPEC mutant lacking the entire effector genes (EPEC0 and intermediate mutants. We show that EPEC0 contains a functional T3SS. An EPEC mutant expressing intimin but lacking all the LEE effectors but Tir (EPEC1 was able to trigger robust actin polymerization in HeLa cells and mucin-producing intestinal LS174T cells. However, EPEC1 was unable to form A/E lesions on human intestinal in vitro organ cultures (IVOC. Screening the intermediate mutants for genes involved in A/E lesion formation on IVOC revealed that strains lacking non-LEE effector/s have a marginal ability to form A/E lesions. Furthermore, we found that Efa1/LifA proteins are important for A/E lesion formation efficiency in EPEC strains lacking multiple effectors. Taken together, these results demonstrate the intricate relationships between T3SS effectors and the essential role non-LEE effectors play in A/E lesion formation on mucosal surfaces.

  3. The Effect of Selected Cleaning Techniques on Berkshire Lee Marble: A Scientific Study at Philadelphia City Hall

    Science.gov (United States)

    Mossotti, Victor G.; Eldeeb, A. Raouf; Fries, Terry L.; Coombs, Mary Jane; Naude, Virginia N.; Soderberg, Lisa; Wheeler, George S.

    2002-01-01

    This report describes a scientific investigation of the effects of eight different cleaning techniques on the Berkshire Lee marble component of the facade of the East Center Pavilion at Philadelphia City Hall; the study was commissioned by the city of Philadelphia. The eight cleaning techniques evaluated in this study were power wash (proprietary gel detergent followed by water rinse under pressure), misting (treatment with potable, nebulized water for 24-36 hours), gommage (proprietary Thomann-Hanry low-pressure, air-driven, small-particle, dry abrasion), combination (gommage followed by misting), Armax (sodium bicarbonate delivered under pressure in a water wash), JOS (dolomite powder delivered in a low-pressure, rotary-vortex water wash), laser (thermal ablation), and dry ice (powdered-dry-ice abrasion delivered under pressure). In our study approximately 160 cores were removed from the building for laboratory analysis. We developed a computer program to analyze scanning-electron-micrograph images for the microscale surface roughness and other morphologic parameters of the stone surface, including the near-surface fracture density of the stone. An analysis of more than 1,100 samples cut from the cores provided a statistical basis for crafting the essential elements of a reduced-form, mixed-kinetics conceptual model that represents the deterioration of calcareous stone in terms of self-organized soiling and erosion patterns. This model, in turn, provided a basis for identifying the variables that are affected by the cleaning techniques and for evaluating the extent to which such variables influence the stability of the stone. The model recognizes three classes of variables that may influence the soiling load on the stone, including such exogenous environmental variables as airborne moisture, pollutant concentrations, and local aerodynamics, and such endogenous stone variables as surface chemistry and microstructure (fracturing, roughness, and so on). This study

  4. Blood values of young Brazilian catfish Pseudoplatystoma corruscans (Agassiz, 1829 - DOI: 10.4025/actascibiolsci.v20i0.4463 Valores sangüíneos de pintados juvenis, Pseudoplatystoma corruscans (Agassiz, 1829 - DOI: 10.4025/actascibiolsci.v20i0.4463

    Directory of Open Access Journals (Sweden)

    Marc Verdegem

    1998-07-01

    Full Text Available Foram analisadas amostras sangüíneas de seis exemplares de Pseudoplatystoma corruscans. As amostras foram coletadas por punção caudal e foram determinados os valores e as médias de hematócrito, leucócrito, eritrócitos e leucócitos e das concentrações protéicas plasmáticas. O plasma sangüíneo foi submetido a eletroforese, para determinação das diferentes frações protéicas. A partir de extensões sangüíneas coradas com métodos rotineiros, cinco tipos celulares puderam ser distinguidos sob microscopia ótica. A média das células sangüíneas totais foi de 1.29 x 106 células.ml-1, enquanto que a concentração protéica média do plasma sangüíneo foi 11.82g.l-1, constituindo-se de cinco frações principais. Essas características hematológicas foram estabelecidas no intuito de se obter um primeiro quadro hematológico da espécie, no qual serão baseados estudos mais aprofundados.The ranges and mean values of haematocrit, leucocrit, red cell, white cell and differential cell counts and serum protein concentration of young growing Pseudoplatystoma corruscans (n=6 were measured, and serum electrophoretic patterns on cellulose acetate described. Blood was obtained by puncture of the caudal vessels. Using routine staining methods, five different cell types could be distinguished by light microscopy. Mean total cell count was 1.29 x 106 cells.ml-1, while mean plasma protein content was 11.82g.l-1 consisting of five major protein fractions. These haematological characteristics were established as a “working document” upon which to base more extensive studies.

  5. Social networks and inference about unknown events: A case of the match between Google's AlphaGo and Sedol Lee.

    Directory of Open Access Journals (Sweden)

    Jonghoon Bae

    Full Text Available This study examines whether the way that a person makes inferences about unknown events is associated with his or her social relations, more precisely, those characterized by ego network density that reflects the structure of a person's immediate social relation. From the analysis of individual predictions over the Go match between AlphaGo and Sedol Lee in March 2016 in Seoul, Korea, this study shows that the low-density group scored higher than the high-density group in the accuracy of the prediction over a future state of a social event, i.e., the outcome of the first game. We corroborated this finding with three replication tests that asked the participants to predict the following: film awards, President Park's impeachment in Korea, and the counterfactual assessment of the US presidential election. Taken together, this study suggests that network density is negatively associated with vision advantage, i.e., the ability to discover and forecast an unknown aspect of a social event.

  6. Economic value of angling on the Colorado River at Lees Ferry: Using secondary data to estimate the influence of seasonality

    Science.gov (United States)

    Bair, Lucas S.; Rogowski, David L.; Neher, Christopher

    2016-01-01

    Glen Canyon Dam (GCD) on the Colorado River in northern Arizona provides water storage, flood control, and power system benefits to approximately 40 million people who rely on water and energy resources in the Colorado River basin. Downstream resources (e.g., angling, whitewater floating) in Glen Canyon National Recreation Area (GCNRA) and Grand Canyon National Park are impacted by the operation of GCD. The GCD Adaptive Management Program was established in 1997 to monitor and research the effects of dam operations on the downstream environment. We utilized secondary survey data and an individual observation travel cost model to estimate the net economic benefit of angling in GCNRA for each season and each type of angler. As expected, the demand for angling decreased with increasing travel cost; the annual value of angling at Lees Ferry totaled US$2.7 million at 2014 visitation levels. Demand for angling was also affected by season, with per-trip values of $210 in the summer, $237 in the spring, $261 in the fall, and $399 in the winter. This information provides insight into the ways in which anglers are potentially impacted by seasonal GCD operations and adaptive management experiments aimed at improving downstream resource conditions.

  7. The contributions of Donald Lee Johnson to understanding the Quaternary geologic and biogeographic history of the California Channel Islands

    Science.gov (United States)

    Muhs, Daniel R.

    2013-01-01

    Over a span of 50 years, native Californian Donald Lee Johnson made a number of memorable contributions to our understanding of the California Channel Islands. Among these are (1) recognizing that carbonate dunes, often cemented into eolianite and derived from offshore shelf sediments during lowered sea level, are markers of glacial periods on the Channel Islands; (2) identifying beach rock on the Channel Islands as the northernmost occurrence of this feature on the Pacific Coast of North America; (3) recognizing of the role of human activities in historic landscape modification; (4) identifying both the biogenic and pedogenic origins of caliche “ghost forests” and laminar calcrete forms on the Channel Islands; (5) providing the first soil maps of several of the islands, showing diverse pathways of pedogenesis; (6) pointing out the importance of fire in Quaternary landscape history on the Channel Islands, based on detailed stratigraphic studies; and (7), perhaps his greatest contribution, clarifying the origin of Pleistocene pygmy mammoths on the Channel Islands, due not to imagined ancient land bridges, but rather the superb swimming abilities of proboscideans combined with lowered sea level, favorable paleowinds, and an attractive paleovegetation on the Channel Islands. Don was a classic natural historian in the great tradition of Charles Darwin and George Gaylord Simpson, his role models. Don’s work will remain important and useful for many years and is an inspiration to those researching the California Channel Islands today.

  8. Pharmacological study of radioactive-gold colloid transport by blood and by serous exudate; Contribution a l'etude pharmacologique du transport des colloides d'or radioactif par le sang et les exsudats sereux

    Energy Technology Data Exchange (ETDEWEB)

    Rousselet, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-06-01

    After giving the essential physico-chemical properties of the colloids, the author considers the biological role of these substances and, in connection with their transport by the blood, their capture by elements of the reticula-endothelial system. A summary is given of present knowledge concerning the role of serous proteins in the transport of substances, particularly that of radio-active colloidal gold. The blood fractions which can take part in colloidal gold transport are the red blood corpuscles, the leukocytes and histiocytic elements as well as the plasma. The radioactive distribution in these various fractions is obtained by autoradiography of blood sediments. After showing the importance of the role of the plasma in radioactive particle transport, the author, describes the attempts made to detect a possible of colloidal gold 198 on the various serous proteins using various methods of separation. The ''in vitro'' and ''in vivo'' bonds between colloidal gold-198 particles and either the serous proteins or healthy specimens or the effusion liquids of pathological origin in man, or due to an experimental inflammation with carregenin in the rat, have been studied. The bonding appears to be effective because of the protective macromolecular layer formed by the gelatine. The different positions of the colloidal grains on the electrophoregram can only be explained by their different physico-chemical characteristics. Gold in the ionic form, on the other hand, is combined only with the albumen is the amount metal present does not exceed a certain value. (author) [French] Apres avoir enonce les proprietes physicochimiques essentielles des colloides nous etudions le devenir biologique de ces substances et, en relation avec leur transport par le sang, leur captation par les elements du Systeme Reticulo-Endothelial. Nous resumons les connaissances acquises jusqu'alors sur le role des proteines seriques dans le transport des

  9. Perfil bioquímico de algumas enzimas no plasma sangüíneo de potras da raça Brasileiro de Hipismo (BH criadas em Colina, Estado de São Paulo

    Directory of Open Access Journals (Sweden)

    Fernando José Benesi

    2009-08-01

    Full Text Available Com o propósito de avaliar o perfil bioquímico de algumas enzimas, em potras sadias da raça BH (Brasileiro de Hipismo, utilizaram-se 380 amostras de plasma sangüíneo colhidas de 19 animais desde o nascimento até 24 meses de vida. Na análise dos resultados evidenciou-se que os valores médios das enzimas FA (fosfatase alcalina e CK (creatina quinase foram máximos entre o nascimento e 24 horas de vida (FA-1995.50 UI/ ; CK-189.13UI/L, enquanto que para a LD (lactato desidrogenase e GGT (gama glutamiltransferase as maiores magnitudes ocorreram, respectivamente, entre 3 e 4 dias (LD-479.11UI/L e aos 10 dias de idade (GGT-18.70UI/L. As FA, CK, LD e GGT, mostraram diminuições dos valores médios, respectivamente, até 6 meses (FA-323.50UI/L, 20 dias (CK-51UI/ L, 19 meses (LD-214.00UI/L e 4 meses (GGT-11.40UI/L estabilizando-se a seguir, com pequenas variações. A atividade da AST (aspartato aminotransferase que foi mínima logo após o nascimento (AST- 43.38UI/L, aumentou até os sete dias de vida (AST-110.89UI/L, e a seguir diminuiu progressivamente, com pequenas oscilações, até o final do estudo. Todas as enzimas avaliadas sofreram variações influenciadas pelo fator etário, particularmente no período inicial de vida dos animais estudados.

  10. Comparison of total polyphenols content and antioxidant potential of wines from ‘Welschriesling’ and ‘Sauvignon Blanc’ varieties during ageing on fine lees

    Directory of Open Access Journals (Sweden)

    Jasna Lužar

    2016-10-01

    Full Text Available Phenolic compounds are key components of wine, since they contribute to wine characteristics such as colour, astringency and bitterness. They also act like antioxidants, with mechanisms involving free-radical scavenging that could prevent cardiovascular diseases and cancer. The aim of the present work was to compare the obtained results of total polyphenols content and antioxidant potential (AOP of several white wines (welschriesling and sauvignon blanc during ageing on fine lees. The total polyphenols content decreased in average for 16.1 % in welschriesling wines and for 18.7 % in sauvignon blanc wines in the period of three months of wine ageing on lees. In the same period AOP of wines decreased in average for 16.0 % in welschriesling wines and for 8.0 % in sauvignon blanc wines. Expectedly, the samples with added oak chips in grape must had higher antioxidant potential than others.

  11. Modelagem conjunta da média e dispersão de Nelder e Lee como alternativa aos métodos de Taguchi

    Directory of Open Access Journals (Sweden)

    Edmilson Rodrigues Pinto

    2006-08-01

    Full Text Available Nos últimos anos, uma coleção de técnicas para a melhoria da qualidade foi desenvolvida, no Japão, por Genichi Taguchi no planejamento, na evolução e na fabricação de produtos industrializados. Esta revolução no campo da qualidade despertou o interesse, no mundo inteiro, de vários engenheiros e estatísticos, que propuseram vários métodos alternativos, mais claros e eficientes do que aqueles propostos por Taguchi. Nelder e Lee observaram que a metodologia de Taguchi conduz a um modelo conjunto para a média e dispersão, usando modelos lineares generalizados. Eles mostraram como esta classe é geral e suficiente para a análise desses modelos. O objetivo deste artigo é fazer uma síntese da modelagem conjunta da média e dispersão, proposta por Nelder e Lee, explicitando, de uma forma concisa, os principais pontos da teoria.In the last years, in Japan, Genichi Taguchi developed some techniques to improve the quality of the products during its design, evolution and manufacture. His ideas have raised the attention of engineers and statisticians around the world who have proposed some alternative methods that are simpler and more efficient than Taguchi's methods. Nelder and Lee observed that Taguchi's methodology lead up to a joint model for the mean and dispersion employing generalized linear models. They showed that this class is general and sufficient to analyze Taguchi's Models. The purpose of this work is to describe joint modeling of mean and dispersion that was proposed by Nelder and Lee and the key points of the theory in a concise manner.

  12. A Rasch Analysis of Assessments of Morning and Evening Fatigue in Oncology Patients Using the Lee Fatigue Scale.

    Science.gov (United States)

    Lerdal, Anners; Kottorp, Anders; Gay, Caryl; Aouizerat, Bradley E; Lee, Kathryn A; Miaskowski, Christine

    2016-06-01

    To accurately investigate diurnal variations in fatigue, a measure needs to be psychometrically sound and demonstrate stable item function in relationship to time of day. Rasch analysis is a modern psychometric approach that can be used to evaluate these characteristics. To evaluate, using Rasch analysis, the psychometric properties of the Lee Fatigue Scale (LFS) in a sample of oncology patients. The sample comprised 587 patients (mean age 57.3 ± 11.9 years, 80% women) undergoing chemotherapy for breast, gastrointestinal, gynecological, or lung cancer. Patients completed the 13-item LFS within 30 minutes of awakening (i.e., morning fatigue) and before going to bed (i.e., evening fatigue). Rasch analysis was used to assess validity and reliability. In initial analyses of differential item function, eight of the 13 items functioned differently depending on whether the LFS was completed in the morning or in the evening. Subsequent analyses were conducted separately for the morning and evening fatigue assessments. Nine of the morning fatigue items and 10 of the evening fatigue items demonstrated acceptable goodness-of-fit to the Rasch model. Principal components analyses indicated that both morning and evening assessments demonstrated unidimensionality. Person-separation indices indicated that both morning and evening fatigue scales were able to distinguish four distinct strata of fatigue severity. Excluding four items from the morning fatigue scale and three items from the evening fatigue scale improved the psychometric properties of the LFS for assessing diurnal variations in fatigue severity in oncology patients. Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  13. Transcriptome analysis of stem development in the tumourous stem mustard Brassica juncea var. tumida Tsen et Lee by RNA sequencing

    Directory of Open Access Journals (Sweden)

    Sun Quan

    2012-04-01

    Full Text Available Abstract Background Tumourous stem mustard (Brassica juncea var. tumida Tsen et Lee is an economically and nutritionally important vegetable crop of the Cruciferae family that also provides the raw material for Fuling mustard. The genetics breeding, physiology, biochemistry and classification of mustards have been extensively studied, but little information is available on tumourous stem mustard at the molecular level. To gain greater insight into the molecular mechanisms underlying stem swelling in this vegetable and to provide additional information for molecular research and breeding, we sequenced the transcriptome of tumourous stem mustard at various stem developmental stages and compared it with that of a mutant variety lacking swollen stems. Results Using Illumina short-read technology with a tag-based digital gene expression (DGE system, we performed de novo transcriptome assembly and gene expression analysis. In our analysis, we assembled genetic information for tumourous stem mustard at various stem developmental stages. In addition, we constructed five DGE libraries, which covered the strains Yong'an and Dayejie at various development stages. Illumina sequencing identified 146,265 unigenes, including 11,245 clusters and 135,020 singletons. The unigenes were subjected to a BLAST search and annotated using the GO and KO databases. We also compared the gene expression profiles of three swollen stem samples with those of two non-swollen stem samples. A total of 1,042 genes with significantly different expression levels occurring simultaneously in the six comparison groups were screened out. Finally, the altered expression levels of a number of randomly selected genes were confirmed by quantitative real-time PCR. Conclusions Our data provide comprehensive gene expression information at the transcriptional level and the first insight into the understanding of the molecular mechanisms and regulatory pathways of stem swelling and development

  14. Staarkleidid / Lee Hanael

    Index Scriptorium Estoniae

    Hanael, Lee

    2008-01-01

    10 maailma kuulsamat kleiti kuulusid Marilyn Monroele, Audrey Hepburnile, printsess Dianale, Vivien Leighle, Tina Turnerile, Julia Robertsile, Liz Hurleyle, Sarah Jessica Parkerile, Keira Knightleyle, Jacqueline Kennedyle

  15. HYDROLOGY, LEE COUNTY, TEXAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a Flood Insurance...

  16. HYDRAULICS, LEE COUNTY, MISSISSIPPI

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  17. HYDROLOGY, LEE COUNTY, MISSISSIPPI

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  18. Erasmusega Eestisse / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2014-01-01

    Prantsuse noormees Théo Brunie õppis Lumière’i ülikoolis Lyonis kommunikatsiooni. Aasta Erasmuse vahetusüliõpilasena Balti Filmi- ja Meediakoolis kasutas ta võimalust õppida kommunikatsiooni koos filmitegemisega

  19. Lee Nnukwu Ukochukwu

    African Journals Online (AJOL)

    User

    Another form of it has more verses sung in the exact fashion as the first. Kpakpando na-amuke and Nni ndi ... A general trend of harmonizing only the chorus or refrain is observed. Only a few works have harmonized .... Something that looks like a second development begins in bar nine. It is a descending move from the ...

  20. Traditsioonist ja uuendusest korea modernkunstis / Katrin Kivimaa

    Index Scriptorium Estoniae

    Kivimaa, Katrin, 1969-

    2005-01-01

    Souli galeriides ja muuseumides valitseb eeldatud kõrgtehnoloogilise kunsti asemel maalikunst. Pikemalt naiskunstnik Wook-kyung Choi (1940-1985) ja Jong-gu Lee näitustest ning soo- ja naisuuringute kongressist "Women's World 2005"

  1. Variações nos níveis das células sangüíneas periféricas encontradas em Holochilus brasiliensis nanus Thomas, 1897, infectados com Schistosoma mansoni Sambon, 1907, próprio da Pré-Amazônia

    OpenAIRE

    Bastos,Othon de Carvalho; Silva,Sônia M. F.; Leal,Grace Mary J. Pires; Bacelar Neto,João M.

    1985-01-01

    Foram constituídos quatro grupos de roedores silvestres para a contagem de células sangüíneas periféricas, da seguinte forma: Grupo I - formado de animais normais, nascidos em biotério, com 30 dias de vida; Grupo II - formado de animais que foram capturados no campo e considerados não infectados com S. mansoni, após ovohelmintoscopia das fezes, realizada durante 30 dias de observação; Grupo III - animáis capturados no campo, nautralmente infectados com o esquistossomo, e o Grupo IV - de anima...

  2. Effect of different forages on blood components of Holstein cows Efeito de diferentes volumosos sobre os constituíntes sangüíneos de vacas da raça holandesa

    Directory of Open Access Journals (Sweden)

    Domenico Sales rocha de Arruda

    2008-04-01

    Full Text Available The effects of three forages on plasma components of Holstein cows were evaluated. Corn silage, alfalfa (Medicago sativa and Tifton-85 (Cynodon spp. hays were used as forage sources. Animal’s weights were obtained at the beginning and end of each experimental period (21d, to evaluate intake and body weight variation during total experimental period. Blood samples (15 mL were obtained on 21d of each period, before morning diet administration, to determine triglycerides, glucose and urea plasma concentration. The experimental design was 3x3 Latin Square with three lines and three columns corresponding to three cows and three roughages. Hematocrit concentration indicated that cows showed light anemia. There was effect of forage source only to triglyceridies concentration.Foram avaliados os efeitos de três volumosos sobre os componentes do plasma sangüíneo de vacas da raça holandesa. Os volumosos utilizados foram à silagem de milho e os fenos de alfafa e de grama tifton-85. Foram realizadas pesagens dos animais no início e final de cada período experimental (21 dias, para medidas do consumo e da variação de peso durante o período total de experimentação. No final do período experimental (21º dia foi coletado uma amostra de aproximadamente 15 mL de sangue, de cada animal, em jejum pela manhã, para a determinação dos níveis plasmáticos de triglicerídeos, glicose e uréia. Para determinação do hematócrito as amostras de sangue foram centrifugadas em tubos capilares, com duas repetições para cada animal. O delineamento experimental utilizado foi um triplo quadrado latino, três linhas e três colunas, com três vacas e três volumosos. As concentrações de hematócritos observadas indicam que as vacas apresentaram leve anemia. Os resultados evidenciaram efeito da fonte de volumoso somente para a concentração de triglicerídeos.

  3. Produção, composição do leite e constituintes sangüíneos de cabras alimentadas com diferentes volumosos Production, milk composition and blood parameters in goats fed different forages

    Directory of Open Access Journals (Sweden)

    L.R. Ribeiro

    2008-12-01

    Full Text Available Utilizaram-se nove cabras da raça Saanen, para estudar o efeito de dietas compostas por três diferentes fontes de volumosos, feno de alfafa, silagem de milho e feno de aveia, sobre a ingestão de matéria seca, produção e composição do leite e sobre os constituintes sangüíneos, glicose e uréia plasmáticas, em triplo quadrado latino 3x3. Os consumos de matéria seca e proteína bruta dos animais alimentados com feno de alfafa foram mais altos que os à base de silagem de milho (P0,05 das dietas sobre a produção diária de leite (kg/dia, sobre os teores (% de gordura, proteína, lactose e sólidos totais e sobre a contagem de células somáticas (cels/mlx1000. Os animais que consumiram feno de alfafa produziram maiores quantidades (P0,05. Os resultados indicaram que a fonte de volumoso, em rações isoenergéticas e isoproteicas, afeta o desempenho dos animais pela alteração no consumo de MS e PB e produção dos constituintes do leite (kg/dia.Nine Saanen dairy goats, consuming diets composed of three different sources of roughage (alfalfa hay, corn silage, and oat hay were used to study the effect of those diets on the ingestion of dry matter (DM, on milk production, milk composition, and plasmatic glucose and urea levels. The experimental design was a triple latin square 3x3. The intakes of DM and crude protein by the animals fed on alfalfa hay were higher than those fed ration based on corn silage (P0.05 of the diets on the daily milk production and on the fat, protein, lactose, and total solids contents, and on the somatic cells count (SCC, but those cows that received diets with alfalfa hay produced higher amounts (g/day (P0.05. It can be concluded that the forage sources affect the animal performance from changes in both DM and CP intakes and production of milk components (kg/day.

  4. Estudo da utilização no pré-operatório de medicamentos ou drogas fitoterápicas que alteram a coagulação sangüínea

    Directory of Open Access Journals (Sweden)

    Marco Willians Baena Destro

    Full Text Available OBJETIVO: Verificar com que freqüência medicamentos e\\ou drogas fitoterápicas que interferem na coagulação sangüínea são utilizados por pacientes que serão submetidos à intervenção cirúrgica e cujo uso não é relatado ao cirurgião; ou quando este é informado não se recomenda a sua interrupção antes da operação. MÉTODO: Estudo quantitativo com variáveis qualitativas, transversal, sobre o uso de medicamentos (AAS e Vitamina E e fitoterápicos (Ginkgo biloba, Alho, Ginseng e Gengibre por parte de 416 pacientes em programação pré-operatória. Desenvolvido no Hospital Universitário de Taubaté (HUT no Hospital Regional de Taubaté (HRT e em um Consultório Particular de Cirurgia Plástica. Estes dados foram obtidos por meio de questionário com perguntas relacionadas ao uso ou não das drogas referidas no último ano e nos 10 dias que antecediam a operação, se o cirurgião foi informado do fato e se houve recomendação médica para a sua suspensão. RESULTADOS: do total pesquisado 58,89% não fizeram uso de alguma das drogas em questão, 39% as usaram no último ano e 13,83% usaram nos últimos 10 dias. O AAS foi o medicamento mais utilizado e dentre os fitoterápicos, o Ginkgo biloba. Do total pesquisado 73,69% dos pacientes não informaram ao cirurgião o uso destas drogas. CONCLUSÕES: Na população estudada é elevada a porcentagem do uso de drogas que interferem na coagulação sanguínea, sendo as mais utilizadas o AAS, a vitamina E e o Ginkgo biloba. A maioria dos pacientes pesquisados não informou ao cirurgião a sua utilização. Deve-se enfatizar a necessidade de pesquisar o uso dessas drogas no pré-operatório, com o objetivo de reduzir possíveis complicações hemorrágicas per e pós-operatórias, pelas suas complicações médicas e eventuais implicações legais.

  5. Numerical experiments on plasma focus for soft x-ray yield scaling laws derivation using Lee model

    International Nuclear Information System (INIS)

    Akel, M.

    2012-09-01

    The required plasma parameters of krypton and xenon at different temperatures were calculated, the x-ray emission properties of plasmas were studied, and based on the corona model the suitable temperature range for generating H-like and He-like ions (therefore soft x-ray emissions) of different gases plasma were found. The code is applied to characterize the plasma focus in different plasma focus devices, and for optimizing the nitrogen, oxygen, neon, argon, krypton and xenon soft x-ray yields based on bank, tubes and operating parameters. It is found that the soft x-ray yield increases with changing pressure until it reaches the maximum value for each plasma focus device. Keeping the bank parameters, operational voltage unchanged but systematically changing other parameters, numerical experiments were performed finding the optimum combination of P o , Z o and 'a' for the maximum soft x-ray yield. Thus we expect to increase the soft x-ray yield of plasma focus device several-fold from its present typical operation; without changing the capacitor bank, merely by changing the electrode configuration and the operating pressure. The Lee model code was also used to run numerical experiments on plasma focus devices for optimizing soft x-ray yield with reducing L o , varying L o and 'a' to get engineering designs with maximum soft x-ray yield for these devices at different experimental conditions and gases. Numerical experiments showed the influence of the gas used in plasma focus and its properties on soft x-ray emission and its properties and then on its applications. Scaling laws for soft x-ray of nitrogen, oxygen, neon, argon, krypton and xenon plasma focus, in terms of energy, peak discharge current and focus pinch current were found. Radiative cooling effects are studied indicating that radiative collapse may be observed for heavy noble gases (Ar, Kr, Xe) for pinch currents even below 100 kA. The results show that the line radiation emission and tube voltages have

  6. ARSITEKTUR "GUNA DAN CITRA" SANG ROMO MANGUN

    Directory of Open Access Journals (Sweden)

    IN MEMORIAM : YUSUF BILYARTA MANGUNWIJAYA

    1999-01-01

    Full Text Available Yusuf Bilyarta Mangunwijaya is not only recognized as a pastor but also as a cultural observer, writer and architect. The architectural works he produced even touch the marginal people. The work does not only result in the physical building but also the total work of human development, "use" and "image". World Architecture never escapes from Vitruvius trilogy saying : Firmitas, Utilitas and Venustas. In his amazing writing, Mangunwijaya offered a distillation of trilogy (three categories into two categories, 'use' and 'image'. This writing is going to impart how the distillation of three categories becomes a 'two-categories. Abstract in Bahasa Indonesia : Yusuf Bilyarta Mangunwijaya tidak saja dikenal sebagai seorang Pastor, tetapi dia juga seorang budayawan, sastrawan, bahkan arsitek. Karya arsitekturnya menyentuh bahkan sampai ke mereka-mereka yang dipinggirkan (kaum marjinal. Karya arsitekturnya tidak saja sebuah sosok bangunan, tetapi sekaligus karya total dengan pembangunan manusianya, "Guna" dan "Citra". Arsitektur dunia tidak dapat melepaskan diri dari Trilogi Vitruvius: Firmitas, utilitas dan venustas. Dalam karya tulisnya yang luarbiasa, Romo Mangunwijaya menyingkatnya hanya dwilogi saja, Guna dan Citra. Tulisan ini akan membahas bagaimana perasan trilogi itu menjadi dwilogi saja. Kata kunci: Mangunwijaya, Vitruvius, guna, citra.

  7. SANG SANGAI : Valokuvausprojektin merkitys nepalilaisille lastenkodin nuorille

    OpenAIRE

    Pakkala, Markus

    2012-01-01

    Tämän opinnäytetyön tarkoitus oli toteuttaa valokuvausprojekti nepalilaisten lastenkodin nuorten kanssa. Valokuvausprojektin taustalla oli keväällä 2010 suoritettu työharjoittelu Kinderhaus–lastenkodissa Kathmandussa. Laadullinen tutkimus, perustuu ohjaajan päiväkirjan havaintoihin, nuorten kirjoittamiin valokuvauspäiväkirjoihin sekä nuorten vastaamaan loppupalautekyselyyn. Dokumentoinnin näkökulma on selvittää, mitä valokuvausprojekti nuorille merkitsee. Kolmen kuukauden mittainen valok...

  8. Sange om krigen - Om komponisten Heiner Goebbels

    DEFF Research Database (Denmark)

    Schultz, Laura Luise

    2011-01-01

    Interview med Heiner Goebbels om hans arbejde med Gertrude Stein-koncerten "Songs of Wars I Have Seen"......Interview med Heiner Goebbels om hans arbejde med Gertrude Stein-koncerten "Songs of Wars I Have Seen"...

  9. 3Corners of the World / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2009-01-01

    Arvustused : Robert Jürjendal, Petri Kuljuntausta, David Rothenberg. 3Corners of the World. [Tallinn] : Terra Nova Music, 2008. Nadia ja Fragile. Uhke ali. [Tallinn] : Nadia & Fragile, 2008. UMA. Civitas Soli. [Tallinn] : Elwood, 2008. Uutest heliplaatidest

  10. Når troen bliver til sang

    DEFF Research Database (Denmark)

    Nielsen, Kirsten

    2009-01-01

    I anmeldelsen fremhæver jeg, at Selander i denne artikelsamling både beskæftiger sig med salmeteksterne og med melodierne. Denne dobbeltkompetence er usædvanlig hos en litteraturforsker. Artiklerne giver et fint indblik i svensk salmetradition samt i komponisternes arbejde med melodierne. Selande...

  11. Dreams of the Hmong Kingdom: The Quest for Legitimation in French Indochina, 1850- 1960, by Mai Na M. Lee. Madison, University of Wisconsin Press, 2015. 430 pages.

    Directory of Open Access Journals (Sweden)

    Nengher N. Vang

    2015-12-01

    Full Text Available This article provides a book review of Mai Na M. Lee’s Dreams of the Hmong Kingdom: The Quest for Legitimation in French Indochina, 1850-1960. Dreams of the Hmong Kingdom. It highlights the contribution of the book to the historiography of the Hmong and provides a critical assessment of the dichotomous analytical framework that Lee uses to analyze the rivalry between Hmong messianic leaders and Hmong political brokers and the competition between the Ly and Lo clans for paramountcy in French Indochina

  12. Lauren Berlant and Lee Edelman, Sex, Or The Unbearable (Durham: Duke University Press, 2014, pp. 168, ISBN: 9780822355946, £13.99, paperback.

    Directory of Open Access Journals (Sweden)

    Hannah Proctor

    2014-01-01

    Full Text Available 'So few colleges and universities bother to teach human sexuality...so much stigma adheres even to scholarly investigation of sex,' Gayle Rubin lamented in her 1984 essay 'Thinking Sex'. But it was an academic conference on Rubin's work - 'Rethinking Sex', a lavish threeday event, held at the University of Pennsylvania in 2009 - that provided the initial impetus for Lauren Berlant and Lee Edelman to enter into a dialogue on sexuality. The result is Sex, or the Unbearable, published by Duke University Press, the first in a series on queer theory edited by the authors.

  13. So lig soos klip. Jacques Pretorius. Kaapstad: Tafelberg, 2012. 224 ...

    African Journals Online (AJOL)

    rasegte buitestaander wat te gou te diep sien. Waar Ratkas se wêreld dié is van die “Graphic. Novel” met sy onderliggende gewelddadig- heid, word die hoofpersoon in Pretorius se roman groot in 'n wêreld van strokiesverhaal- helde. Vroeg reeds droom hy dat hy kan ontsnap uit sy ongelukkige bestaan waar sy ma hom.

  14. Gevalle van positiewe taalbeplanning soos gerapporteer in die ...

    African Journals Online (AJOL)

    A distinction is made between positive language planning by official and private institutions. Official institutions are statutorily compelled to comply with the language clauses of the Constitution, while private institutions are not bound by these stipulations. The relatively small proportion of cases of positive language planning, ...

  15. 'n Godsleer van Openbaring soos vervat in die himnes

    Directory of Open Access Journals (Sweden)

    E. Meyer

    1997-07-01

    Full Text Available A Theology of Revelations as imbedded in the hymns. This anicle is based on a twofold hypothesis, namely that the author of Revelation not only wrote the hymns in this book,' he also used them specifically to express his theology. The narrator utilises the hymnes to lay words in the mouths of the characters in order to establish a complete theology as well as christology. These hymns can even be used today to offer mankind real hope by calling one and all to the centre and true reason for our existence: Worship God!

  16. Liturgie soos in die GKSA beoefen krities bekyk

    Directory of Open Access Journals (Sweden)

    B. Spoelstra

    1994-06-01

    Full Text Available This article attempts a further analysis of the current liturgical procedure and position of the so-called worship service in the Reformed Churches of South Africa (GKSA. In this article the acts or decisions of at least three Synods of the GKSA dealing with the so-called ‘elements' of a worship service (erediens are analysed. It is argued that the liturgical procedure inherited from the Netherlands often fails to constitute a real encounter in worship between God and his congregation. A one-sided intellectual and instructional emphasis on the sermon is to be blamed for this failure.

  17. Die priesterskap van die gelowiges soos Calvyn dit gesien het

    Directory of Open Access Journals (Sweden)

    A. D. Pont

    1989-01-01

    Full Text Available The priesthood of all believers as seen by Calvin The Lutheran thesis of the priesthood of all believers was also taken over by John Calvin. The position of this thesis in Calvin’s theology is examined and it is shown that Calvin does not trea t this thesis as a separate statement. A short introduction is given of the main points Calvin explores when he discusses the meaning of the thesis. In the end it is shown that Calvin developed the thesis of the universal priesthood in such a low-key form to preserve the order in the Church and the prime position of the preaching of the gospel.

  18. Topography and vegetation as predictors of snow water equivalent across the alpine treeline ecotone at Lee Ridge, Glacier National Park, Montana, U.S.A.

    Science.gov (United States)

    Geddes, C.A.; Brown, D.G.; Fagre, D.B.

    2005-01-01

    We derived and implemented two spatial models of May snow water equivalent (SWE) at Lee Ridge in Glacier National Park, Montana. We used the models to test the hypothesis that vegetation structure is a control on snow redistribution at the alpine treeline ecotone (ATE). The statistical models were derived using stepwise and "best" subsets regression techniques. The first model was derived from field measurements of SWE, topography, and vegetation taken at 27 sample points. The second model was derived using GIS-based measures of topography and vegetation. Both the field- (R² = 0.93) and GIS-based models (R² = 0.69) of May SWE included the following variables: site type (based on vegetation), elevation, maximum slope, and general slope aspect. Site type was identified as the most important predictor of SWE in both models, accounting for 74.0% and 29.5% of the variation, respectively. The GIS-based model was applied to create a predictive map of SWE across Lee Ridge, predicting little snow accumulation on the top of the ridge where vegetation is scarce. The GIS model failed in large depressions, including ephemeral stream channels. The models supported the hypothesis that upright vegetation has a positive effect on accumulation of SWE above and beyond the effects of topography. Vegetation, therefore, creates a positive feedback in which it modifies its, environment and could affect the ability of additional vegetation to become established.

  19. Samuel Holden Parsons Lee (1772-1863): American physician, entrepreneur and selfless fighter of the 1798 Yellow Fever epidemic of New London, Connecticut.

    Science.gov (United States)

    Mattie, James K; Desai, Sukumar P

    2015-02-01

    Samuel Holden Parsons Lee practised medicine at a time when the germ theory of disease had not yet been proposed and antibiotics remained undiscovered. In 1798 he served selflessly as the only physician in town who was willing to battle the Yellow Fever outbreak of New London, Connecticut. Because he practised at the dawn of the age of patent medicine, unfortunately his name also came to be associated with medical quackery. We argue that his contributions have been grossly underestimated. He compounded and vended medications - including bilious pills and bitters - that were gold standards of the day. Moreover, one preparation for treatment of kidney stones led to his sub-specialization in this field and was met with such success that its sale continued for nearly 100 years after his death. While a talented medical man, Lee also had a knack for business, finding success in trading, whaling and real estate. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  20. South African Journal for Research in Sport, Physical Education and ...

    African Journals Online (AJOL)

    Analysis of shots on target and goals scored in soccer matches: Implications for coaching and training goalkeepers · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Young-Soo Park, Man-Sik Choi, Sang-Yeol Bang, Jeong-Keun Park, 123-137 ...

  1. Análise direcional do fluxo sangüíneo miocárdico após revascularização transmiocárdica com laser de CO2: estudo através da ressonância magnética com imagens de gradiente ultra-rápido

    Directory of Open Access Journals (Sweden)

    DALLAN Luís A.

    2002-01-01

    Full Text Available OBJETIVO: Avaliar a direção do fluxo sangüíneo miocárdico de pacientes submetidos à revascularização transmiocárdica com laser de CO2 (RTML, através de estudos de imagem por ressonância magnética. CASUÍSTICA E MÉTODOS: Dez pacientes submetidos a RTML com laser de CO2 (potência de 800 W foram estudados através da ressonância magnética de gradiente ultra-rápido (Gradiente eco-EPI de seqüência híbrida, visando avaliar o direcionamento da perfusão miocárdica após o procedimento. Gadolínio - DTPA (0,1 mmol/kg foi injetado "em bolus" através de veia periférica em velocidade de 5 ml/seg em repouso durante o pico de "stress" induzido por dipiridamol. Foi avaliada sua distribuição miocárdica através da obtenção de curvas de intensidade de sinal no tempo para as diversas sub-regiões do miocárdio, em modelo de 24 segmentos. RESULTADOS: Após período médio de 14,7 meses, pudemos detectar isquemia em ao menos uma das paredes ventriculares em 6 (60% pacientes. Em 1 (10% paciente pode-se notar que o fluxo sangüíneo miocárdico dirigia-se do subendocárdio para o subepicárdio, ao contrário dos demais. CONCLUSÃO: A ressonância magnética, usando a técnica de perfusão miocárdica de primeira passagem, permitiu observar o direcionamento do fluxo sangüíneo miocárdico. Em um dos pacientes, a presença de fluxo miocárdico invertido (do endocárdio para o epicárdio sugeriu a patência dos canais realizados através da RTML.

  2. Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM pilot): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Sackley, Catherine M; Smith, Christina H; Rick, Caroline; Brady, Marian C; Ives, Natalie; Patel, Ramilla; Roberts, Helen; Dowling, Francis; Jowett, Sue; Wheatley, Keith; Patel, Smitaa; Kelly, Debbie; Sands, Gina; Clarke, Carl

    2014-06-07

    Parkinson's disease is a common movement disorder affecting approximately 127,000 people in the UK, with an estimated two thirds having speech-related problems. Currently there is no preferred approach to speech and language therapy within the NHS and there is little evidence for the effectiveness of standard NHS therapy or Lee Silverman voice treatment. This trial aims to investigate the feasibility and acceptability of randomizing people with Parkinson's disease-related speech or voice problems to Lee Silverman voice treatment or standard speech and language therapy compared to a no-intervention control. The PD COMM pilot is a three arm, assessor-blinded, randomized controlled trial. Randomization will be computer-generated with participants randomized at a ratio of 1:1:1. Participants randomized to intervention arms will be immediately referred to the appropriate speech and language therapist. The target population are patients with a confirmed diagnosis of idiopathic Parkinson's disease who have problems with their speech or voice. The Lee Silverman voice treatment intervention group will receive the standard regime of 16 sessions between 50 and 60 minutes in length over four weeks, with extra home practice. The standard speech and language therapy intervention group will receive a dose determined by patients' individual needs, but not exceeding eight weeks of treatment. The control group will receive standard care with no speech and language therapy input for at least six months post-randomization. Outcomes will be assessed at baseline (pre-randomization) and post- randomization at three, six, and 12 months. The outcome measures include patient-reported voice measures, quality of life, resource use, and assessor-rated speech recordings. The recruitment aim is at least 60 participants over 21 months from 11 sites, equating to at least 20 participants in each arm of the trial. This trial is ongoing and recruitment commenced in May 2012. This study will

  3. Comparisons of predictive values of sarcopenia with different muscle mass indices in Korean rural older adults: a longitudinal analysis of the Aging Study of PyeongChang Rural Area

    Directory of Open Access Journals (Sweden)

    Jang IY

    2018-01-01

    Full Text Available Il-Young Jang,1,2,* Hee-Won Jung,3,4,* Chang Ki Lee,5 Sang Soo Yu,2 Young Soo Lee,1 Eunju Lee1 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 2PyeongChang Health Center & County Hospital, Gangwon-Do, 3Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST, Daejeon, 4Geriatric Center, Seoul National University Bundang Hospital, Gyeonggi-Do, 5Goldman Urology Clinic, Seoul, Republic of Korea *These authors contributed equally to this work Purpose: It is important to define lean muscle mass when diagnosing sarcopenia, but there is still controversy on the clinical implication of sarcopenia derived by height, weight, and body mass index (BMI adjusted muscle mass indices. We aimed to evaluate the longitudinal clinical relevance of 3 sarcopenia definitions in the Korean population. Patients and methods: We conducted comprehensive geriatric assessments for 1,379 community-dwelling older participants in the Aging Study of PyeongChang Rural Area (ASPRA cohort and followed them up prospectively for death, institutionalization, and disability every 3 months. Sarcopenia was defined using the Asian Working Group consensus algorithm, combining grip strength, gait speed, and muscle mass.Results: Among 1,343 participants (mean age: 76 years, 741 women analyzed, there were 29 deaths and 89 institutionalizations during 22.0 ± 8.3 months follow-up (mean ± SD. All three muscle indices correlated to age and sex. All sarcopenia criteria with muscle mass indices of height, weight, and body mass index (BMI adjustment significantly predicted death or institutionalization. However, when adjusted for age and sex, only the sarcopenia criteria with muscle mass index of height adjustment were significantly associated with major adverse health outcomes.Conclusion: Adjusting age and gender, the sarcopenia definition from the quintile-based muscle index of height

  4. Diagnosis of prostate cancer via nanotechnological approach

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    Kang BJ

    2015-10-01

    Full Text Available Benedict J Kang,1,2,* Minhong Jeun,1,2,* Gun Hyuk Jang,1,2 Sang Hoon Song,3 In Gab Jeong,3 Choung-Soo Kim,3 Peter C Searson,4 Kwan Hyi Lee1,2 1KIST Biomedical Research Institute, 2Department of Biomedical Engineering, Korea University of Science and Technology (UST, 3Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 4Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA *These authors contributed equally to this work Abstract: Prostate cancer is one of the leading causes of cancer-related deaths among the Caucasian adult males in Europe and the USA. Currently available diagnostic strategies for patients with prostate cancer are invasive and unpleasant and have poor accuracy. Many patients have been overly or underly treated resulting in a controversy regarding the reliability of current conventional diagnostic approaches. This review discusses the state-of-the-art research in the development of novel noninvasive prostate cancer diagnostics using nanotechnology coupled with suggested diagnostic strategies for their clinical implication.Keywords: bioassay, nanomaterial, nanodevice, PSA, non-PSA biomarker, bodily fluid

  5. Reference values for chinchilla (Chinchilla laniger blood cells and serum biochemical parameters Valores de referência para os parâmetros das células e bioquímica sangüínea da chinchila (Chinchilla laniger

    Directory of Open Access Journals (Sweden)

    Tális de Oliveira Silva

    2005-06-01

    Full Text Available Raising chinchilla (Chinchilla laniger for commercial purpose has increased significantly; however, hematological and serum biochemical reference values have not yet been determined for chinchillas raised in south Brazil. Establishing blood cells and serum biochemistry reference values might be helpful to evaluate health status of chinchillas and might be used as a tool by clinicians. The purpose of this study was to determine the reference values for blood cells and serum biochemistry of Chinchilla laniger. Blood samples were collected by cardiac puncture from 16 adult males, at the time they were killed to remove the fur coat, and from 8 adult males anesthetized with ketamine and xylazine. Blood cell counts and serum biochemistry analysis were performed using standard techniques and the results were expressed as mean ± SEM. Analysis of blood parameters from post-mortem cardiac punctured and from anesthetized chinchillas indicated that blood samples from anesthetized chinchillas had higher PCV, Hemoglobin, MCHC and WBC (P A criação de chinchila (Chinchilla laniger com objetivos comerciais tem crescido muito nos últimos anos. No entanto, os valores de referência para os parâmetros hematológicos e bioquímicos não foram ainda determinados para chinchilas criados no sul do Brasil. O estabelecimento dos valores de referência para esses parâmetros pode servir de auxílio para a avaliação da saúde das chinchilas e servir de auxílio diagnóstico para o clínico. Esse estudo teve como objetivo determinar os valores de referência das células e da bioquímica sangüínea da Chinchilla laniger. As amostras de sangue foram coletadas por meio de punção cardíaca de 16 machos adultos no momento em que os animais foram mortos para remoção da pele, e de 8 machos adultos após anestesia com xylazina e ketamina. A contagem das células sangüíneas e a análise dos parâmetros bioquímicos foram feitas utilizando-se métodos padronizados em

  6. Interferência dos ácidos graxos ômega-3 nos lipídeos sangüíneos de ratos submetidos ao exercício de natação Omega-3 fatty acids interference on the blood lipids of rats subjected to swimming exercise

    OpenAIRE

    Bettina Moritz; Elisabeth Wazlawik; Jaqueline Minatti; Rafaella Cristina Dimbarre de Miranda

    2008-01-01

    OBJETIVO: Investigar os efeitos da suplementação com ácidos graxos ômega-3, nas doses de 0,5 e 1,0g/kg/dia, nos lipídeos sangüíneos de ratos submetidos ou não ao protocolo do nado. MÉTODOS: Ratos Wistar foram divididos em grupos: controle, controle+nado, ácidos graxos ômega-3 e ácidos graxos ômega-3+nado. Os ácidos graxos ômega-3 e ácidos graxos ômega-3+nado receberam suplementação; os demais receberam água por gavagem. Os controle+nado e ácidos graxos ômega-3+nado foram submetidos ao exercíc...

  7. Reorientando a identidade nacional em Native speaker, de Chang-rae Lee, e O sol se põe em São Paulo, de Bernardo Carvalho

    Directory of Open Access Journals (Sweden)

    Rex P. Nielson

    2014-01-01

    Full Text Available A comparative reading of the novels Native speaker (1995, by the North American writer Chang-rae Lee, and O sol se põe em São Paulo (2007, by Bernardo Carvalho, allows for a reevaluation of how minority identities have been constructed in the two American megalopolises New York and São Paulo. The plotlines of both nove ls hinge on the identity crisis of a second-generation Asian immigrant (from Korea in one case and Japan in the other who is seeking to negotiate his American identity (speaking in hemispheric terms in terms of his family‟s origin and language. However, despite the similar anxieties over assimilation present in both novels, they both reveal significant differences regarding the ways in which the United States and Brazil have responded to cultural difference even as they challenge national myths of inclusi on and belonging.

  8. Samsung : Lee Byung Chull, créateur d’un modèle mondial (1938-1987)

    OpenAIRE

    Park-Barjot, Rang-Ri

    2012-01-01

    Samsung, la firme aux « trois étoiles », a été fondée en 1938 par Lee Byung Chull, un entrepreneur d’exception. D’abord connu pour ses produits bas de gamme et bon marché, le groupe s’est imposé à la pointe de la technologie grâce à un modèle industriel efficace. En dépit de sa diversification, Samsung est devenu l’un des leaders mondiaux de l’ère numérique. Samsung a réalisé une spectaculaire percée dans l’électrotechnique et l’électronique, à travers sa filiale Samsung Electronics, leader m...

  9. Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-κB activation.

    Science.gov (United States)

    Royan, Sandhya V; Jones, Rheinallt M; Koutsouris, Athanasia; Roxas, Jennifer L; Falzari, Kanakeshwari; Weflen, Andrew W; Kim, Amy; Bellmeyer, Amy; Turner, Jerrold R; Neish, Andrew S; Rhee, Ki-Jong; Viswanathan, V K; Hecht, Gail A

    2010-12-01

    Enteric bacterial pathogens have evolved sophisticated strategies to evade host immune defences. Some pathogens deliver anti-inflammatory effector molecules into the host cell cytoplasm via a type III secretion system (T3SS). Enteropathogenic Escherichia coli (EPEC) inhibits inflammation by an undefined, T3SS-dependent mechanism. Two proteins encoded outside of the EPEC locus of enterocyte effacement (LEE) pathogenicity island, non-LEE-encoded effector H1 (NleH1) and H2 (NleH2), display sequence similarity to Shigella flexneri OspG, which inhibits activation of the pro-inflammatory transcription factor NF-κB. We hypothesized that the anti-inflammatory effects of EPEC were mediated by NleH1 and NleH2. In this study, we examined the effect of NleH1/H2 on the NF-κB pathway. We show that NleH1/H2 are secreted via the T3SS and that transfection of cells with plasmids harbouring nleH1 or nleH2 decreased IKK-β-induced NF-κB activity and attenuated TNF-α-induced degradation of phospho-IκBα by preventing ubiquitination. Serum KC levels were higher in mice infected with ΔnleH1H2 than those infected with WT EPEC, indicating that NleH1/H2 dampen pro-inflammatory cytokine expression. ΔnleH1H2 was cleared more rapidly than WT EPEC while complementation of ΔnleH1H2 with either NleH1 or NleH2 prolonged colonization. Together, these data show that NleH1 and NleH2 function to dampen host inflammation and facilitate EPEC colonization during pathogenesis. © 2010 Blackwell Publishing Ltd.

  10. Practical aspects of Lee Goldburg based CRAMPS techniques for high-resolution 1H NMR spectroscopy in solids: Implementation and applications

    Science.gov (United States)

    Coelho, Cristina; Rocha, João; Madhu, P. K.; Mafra, Luís

    2008-10-01

    Elucidating the local environment of the hydrogen atoms is an important problem in materials science. Because 1H spectra in solid-state nuclear magnetic resonance (NMR) suffer from low resolution due to homogeneous broadening, even under magic-angle spinning (MAS), information of chemical interest may only be obtained using certain high-resolution 1H MAS techniques. 1H Lee-Goldburg (LG) CRAMPS (Combined Rotation And Multiple-Pulse Spectroscopy) methods are particularly well suited for studying inorganic-organic hybrid materials, rich in 1H nuclei. However, setting up CRAMPS experiments is time-consuming and not entirely trivial, facts that have discouraged their widespread use by materials scientists. To change this status quo, here we describe and discuss some important aspects of the experimental implementation of CRAMPS techniques based on LG decoupling schemes, such as FSLG (Frequency Switched), and windowed and windowless PMLG (Phase Modulated). In particular, we discuss the influence on the quality of the 1H NMR spectra of the different parameters at play, for example LG (Lee-Goldburg) pulses, radio-frequency ( rf) phase, frequency switching, and pulse imperfections, using glycine and adamantane as model compounds. The efficiency and robustness of the different LG-decoupling schemes is then illustrated on the following materials: organo-phosphorus ligand, N-(phosphonomethyl)iminodiacetic acid [H 4pmida] [I], and inorganic-organic hybrid materials (C 4H 12N 2)[Ge 2(pmida) 2OH 2]·4H 2O [II] and (C 2H 5NH 3)[Ti(H 1.5PO 4)(PO 4)] 2·H 2O [III].

  11. Mesophilic and thermophilic anaerobic co-digestion of winery wastewater sludge and wine lees: An integrated approach for sustainable wine production.

    Science.gov (United States)

    Da Ros, C; Cavinato, C; Pavan, P; Bolzonella, D

    2017-12-01

    In this work, winery wastes generated by a cellar producing approximately 300,000 hL of wine per year was monitored for a period of one year. On average, 196 L of wastewater, 0.1 kg of waste activated sludge (dry matter) and 1.6 kg of wine lees were produced per hectoliter of wine produced. Different winery wastes, deriving from different production steps, namely waste activated sludge from wastewater treatment and wine lees, were co-treated using an anaerobic digestion process. Testing was conducted on a pilot scale for both mesophilic and thermophilic conditions. The process was stable for a long period at 37 °C, with an average biogas production of 0.386 m 3 /kg COD fed . On the other hand, for thermophilic conditions, volatile fatty acids accumulated in the reactor and the process failed after one hydraulic retention time (23 days). In order to fix the biological process, trace elements (iron, cobalt and nickel) were added to the feed of the thermophilic reactor. Metals augmentation improved process stability and yields at 55 °C. The pH ranged between 7.8 and 8.0, and specific gas production was 0.450 m 3 /kg COD fed , which corresponded to dry matter and COD removals of 34% and 88%, respectively. Although the observed performances in terms of biogas production were good, the thermophilic process exhibited some limitations related to both the necessity of metals addition and the worse dewaterability properties. In fact, while the mesophilic digestates reached a good dewatering quality via the addition of 6.5 g of polymer per kg of dry matter, the required dosage for the thermophilic sludge was greater than 10 g/kg of dry matter. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Tratamento dos distúrbios da voz na doença de Parkinson: o método Lee Silverman

    Directory of Open Access Journals (Sweden)

    Dias Alice Estevo

    2003-01-01

    Full Text Available Alterações discretas na qualidade da voz e da articulação podem ser observadas em fases relativamente iniciais da doença de Parkinson (DP. As alterações da voz e da fala na DP constituem, em conjunto, o que se denomina disartria hipocinética ou disartrofonia e caracterizam-se por monotonia e redução da intensidade da voz, articulação imprecisa e distúrbios do ritmo. Recentemente, foram relatados resultados favoráveis através de método de tratamento intensivo e dirigido especificamente para o tratamento da voz na DP, denominado Lee Silverman Voice Treatment (LSVT®. O objetivo essencial desse método é aumentar a intensidade vocal através do incremento do esforço fonatório. O presente estudo teve por objetivo a caracterização das anormalidades vocais (qualidade vocal, padrão articulatório e inteligibilidade em um grupo de pacientes com DP e a avaliação da resposta terapêutica obtida pela administração do método Lee Silverman. A comparação dos dados de análise acústica, bem como da análise perceptivo-auditiva nos períodos pré e pós-tratamento mostraram modificações estatisticamente significantes após o tratamento. Embora o padrão articulatório tenha se mantido impreciso, os benefícios obtidos pelo tratamento na melhora da qualidade vocal e, sobretudo, na intensidade vocal favoreceram a qualidade da comunicação oral, reduziram os sintomas negativos e adequaram a qualidade vocal às necessidades pessoais e sociais dos indivíduos.

  13. Non Linear Effects of Applied Loads and Large Deformations on Aircraft Normal Modes

    Science.gov (United States)

    2000-05-01

    with increasing tip deflections. solution 106 of MSC/ NASTRAN in combination with These figures are relevant because they reflect some of several DMAP ...MSC/ NASTRAN Handbook for Nonlinear Analysis. (Draft) Version 67. Sang H. Lee, Editor. March 31, 1992.

  14. Bomba sangüínea espiral: concepção, desenvolvimento e aplicação clínica de projeto original Spiral blood pump: conception, development and clinical application of the original project

    Directory of Open Access Journals (Sweden)

    Jarbas J. Dinkhuysen

    2007-06-01

    Full Text Available INTRODUÇÃO: O trabalho aborda projeto original relativo à concepção, ao desenvolvimento e à aplicação clínica de bomba sangüínea que associa forças centrífuga e axial de propulsão hidráulica, baseada no princípio de Arquimedes, denominada Bomba Espiral (BE, tendo recebido Patente Nacional e Relatório Preliminar Internacional categorizando-a como invento. MÉTODO: Visa avaliar sua capacidade hidrodinâmica e seu impacto aos elementos figurados do sangue por meio de testes "in vitro", como Eficiência Hidrodinâmica, Hemólise Normalizada e Visibilização de Escoamento, e, nos testes "in vivo" experimentais, feitos em carneiros submetidos a Circulação Extracorpórea (CEC, e clínico, em 43 pacientes submetidos a operações cardíacas com CEC, nas quais o elemento propulsor foi a BE. RESULTADOS: Na dependência da distância entre o rotor e a carcaça (fenda da bomba pôde-se observar que com 1,5 mm gerou escoamento ao redor de 9 L/min, pressão acima de 400mmHg com 1500 rotações por minuto (rpm, índices de Hemólise Normalizada não superiores a 0,0375 g/100l em condições de alto fluxo e pressão, e pelo estudo de Visibilização do Escoamento no interior da bomba não se detectou áreas de estagnação ou turbulência na entrada, saída e junto à extremidade dos fusos. Nas pesquisas "in vivo" experimentais em ovinos em CEC por 6 horas a BE foi capaz de manter parâmetros pressóricos adequados e Hemoglobina Livre entre 16,36 mg% e 44,90 mg%. Durante sua aplicação em cirurgias cardíacas com CEC, num grupo de 43 pacientes, pôde-se constatar variações pré e pós-CEC, na Hemoglobina Livre de 9,34 a 44,16 mg%, no Fibrinogênio, de 236,65 a 547,26 mg%, na contagem do número de Plaquetas de 152,465 a 98,139, Desidrogenase Láctica, de 238,12 a 547,26 mg%, com tempo de coagulação ativada ao redor de 800 seg. quando em CEC. CONCLUSÕES: A BE mostrou resolutividade por gerar escoamento e pressão adequados, sem causar

  15. Metabolismo miocárdico após cardioplegia sangüínea hipotérmica retrógrada contínua Myocardial metabolism after hypothermic retrograde continuous blood cardioplegia

    Directory of Open Access Journals (Sweden)

    Claudio G. SOBROSA

    2000-09-01

    Full Text Available CASUÍSTICA E MÉTODOS: Realizamos uma análise metabólica da cardioplegia sangüínea hipotérmica retrógrada contínua em um estudo prospectivo de 15 pacientes consecutivos encaminhados para operação eletiva de revascularização miocárdica. Os critérios de inclusão foram doença coronária bi ou triarterial e função ventricular preservada (FE > 40%. Os critérios de exclusão foram angina instável, diabéticos insulino-dependentes e operações associadas. Três pacientes foram excluídos do trabalho (operação associada e deslocamento do cateter de cardioplegia retrógrada. Amostras de sangue arterial e do seio coronário foram simultaneamente colhidas: antes do início da CEC, na abertura da aorta e com 10, 30 e 60 minutos de reperfusão, para análise do conteúdo de oxigênio e da concentração de lactato. Quatro biópsias miocárdicas foram obtidas do ápice do ventrículo esquerdo: (1 após instalação da CEC (mas antes do pinçamento aórtico, (2 imediatamente após o término da indução cardioplégica, (3 antes do despinçamento aórtico e (4 com 30 minutos de reperfusão, para análise dos níveis de ATP, ADP, AMP e lactato no miocárdio. A isoenzima CK-MB foi analisada no sangue venoso. RESULTADOS: Não houve mortalidade no grupo. Houve uma diminuição da extração artério-venosa do lactato e do oxigênio pelo coração durante a reperfusão, somente havendo uma recuperação parcial ao final de 60 minutos de reperfusão. O ATP e os outros nucleotídeos tiveram os seus níveis mantidos no miocárdio durante o pinçamento aórtico, mas estes caíram nos primeiros 30 minutos de reperfusão. O lactato acumulou-se no músculo cardíaco durante o pinçamento aórtico e diminuiu durante a reperfusão. Houve um aumento da enzima CK-MB, principalmente entre a terceira e sexta horas de pós-operatório. CONCLUSÕES: Do ponto de vista metabólico, o método não evitou o metabolismo anaeróbico durante o período de pin

  16. The effects of Hurricane Irene and Tropical Storm Lee on the bed sediment geochemistry of U.S. Atlantic coastal rivers

    Science.gov (United States)

    Horowitz, Arthur J.

    2013-01-01

    Hurricane Irene and Tropical Storm Lee, both of which made landfall in the U.S. between late August and early September 2011, generated record or near record water discharges in 41 coastal rivers between the North Carolina/South Carolina border and the U.S./Canadian border. Despite the discharge of substantial amounts of suspended sediment from many of these rivers, as well as the probable influx of substantial amounts of eroded material from the surrounding basins, the geochemical effects on the wastewater/solid sludge. The limited number of significant sediment-associated chemical changes that were detected probably resulted from two potential processes: (1) the flushing of in-stream land-use affected sediments that were replaced by baseline material more representative of local geology and/or soils (declining concentrations), and/or (2) the inclusion of more heavily affected material as a result of urban nonpoint-source runoff and/or releases from flooded treatment facilities (increasing concentrations). Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

  17. Social networks and inference about unknown events: A case of the match between Google’s AlphaGo and Sedol Lee

    Science.gov (United States)

    Bae, Jonghoon; Cha, Young-Jae; Lee, Hyungsuk; Lee, Boyun; Baek, Sojung; Choi, Semin

    2017-01-01

    This study examines whether the way that a person makes inferences about unknown events is associated with his or her social relations, more precisely, those characterized by ego network density that reflects the structure of a person’s immediate social relation. From the analysis of individual predictions over the Go match between AlphaGo and Sedol Lee in March 2016 in Seoul, Korea, this study shows that the low-density group scored higher than the high-density group in the accuracy of the prediction over a future state of a social event, i.e., the outcome of the first game. We corroborated this finding with three replication tests that asked the participants to predict the following: film awards, President Park’s impeachment in Korea, and the counterfactual assessment of the US presidential election. Taken together, this study suggests that network density is negatively associated with vision advantage, i.e., the ability to discover and forecast an unknown aspect of a social event. PMID:28222114

  18. Time-lapse analysis of methane quantity in Mary Lee group of coal seams using filter-based multiple-point geostatistical simulation

    Science.gov (United States)

    Karacan, C. Özgen; Olea, Ricardo A.

    2013-01-01

    Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area.

  19. Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil Infecção na corrente sangüínea por Candida spp. dados de um hospital universitário em Mato Grosso do Sul, Brasil

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    Marilene Rodrigues Chang

    2008-10-01

    Full Text Available The incidence of Candida bloodstream infection has increased over the past years. In the Center-West region of Brazil, data on candidemia are scarce. This paper reports a retrospective analysis of 96 cases of Candida bloodstream infection at a Brazilian tertiary-care teaching hospital in the state of Mato Grosso do Sul, from January 1998 to December 2006. Demographic, clinical and laboratory data were collected from medical records and from the hospital's laboratory database. Patients' ages ranged from three days to 92 years, with 53 (55.2% adults and 43 (44.8% children. Of the latter, 25 (58.1% were newborns. The risk conditions most often found were: long period of hospitalization, utilization of venous central catheter, and previous use of antibiotics. Fifty-eight (60.4% patients died during the hospitalization period and eight (13.7% of them died 30 days after the diagnosis of candidemia. Candida albicans (45.8% was the most prevalent species, followed by C. parapsilosis (34.4%, C. tropicalis (14.6% and C. glabrata (5.2%. This is the first report of Candida bloodstream infection in the state of Mato Grosso do Sul and it highlights the importance of considering the possibility of invasive Candida infection in patients exposed to risk factors, particularly among neonates and the elderly.RESUMO A incidência de infecções na corrente sangüínea causada por Candida spp. tem aumentado nos últimos anos. Na região Centro-Oeste do Brasil, os dados sobre candidemia são escassos. Realizamos uma análise retrospectiva de casos de infecção na corrente sangüínea por Candida em um hospital terciário de ensino de Mato Grosso do Sul. Noventa e seis episódios diagnosticados de janeiro de 1998 a dezembro de 2006 foram incluídos no estudo. Os dados demográficos e clínicos foram obtidos de prontuários; os dados laboratoriais provieram de registros do laboratório hospitalar. Dos pacientes, 43 (44,8% eram crianças e 53 (55,2% adultos, com idades

  20. Estudo de grupos sangüíneos em doadores de sangue caucasóides e negróides na cidade de São Paulo Blood groups in caucasian and black blood donors from São Paulo, Brazil

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    Marcia C. Z. Novaretti

    2000-04-01

    Full Text Available Apesar do fato de que o grupo de mulatos representa um dos mais comuns grupos raciais encontrados não só no Brasil, mas em vários outros países, existe pouca informação sobre a distribuição dos grupos sangüíneos nestes indivíduos. Foram estudados 2.462 doadores de sangue classificados como caucasóides, mulatos e negros conforme suas características antropológicas, bem como pela suas informações sobre seus ancestrais. Foram estudadas as freqüências fenotípicas para os sistemas de grupos sangüíneos ABO, Rh, P, Kell, Rh, Lutheran, Lewis, Duffy e Kidd. Não foram encontradas diferenças estatisticamente significativas entre negros e mulatos para a maioria dos sistemas de grupos sangüíneos por nós estudados, com exceção dos seguintes fenótipos: P1 positivo, Dccee, Le(a-b-, Js(a+b+, Js(a-b+, Fy(a-b-, Fy(a+b+ e Fy(a-b+. Por outro lado foi observada uma diferença estatisticamente significante entre caucasóides e negróides para os seguintes fenótipos eritrocitários: A, B, M+N-S+s-, M+N-S-s+, P1 positivo, ddccee, Dccee, Dccee, DCCee, DccEe, K+k+, K-k+, Kp(a-b+, Kp(a+b+, Js(a-b+, Js(a+b-, Le(a-b+, Le(a-b-, Fy(a-b+, Fy(a+b+, Fy(a-b-, Jk(a+b-, Jk(a+b+ e Jk(a-b+. Os resultados encontrados para o grupo mulato foram intermediários entre caucasóides e negros, com forte influência negróide.Despite the fact Mulattos (individuals resulting from admixture of Caucasian and Black individuals represent one of the most common racial mixed individuals not only in Brazil but in many other countries, there is little information regarding the distribution of blood groups among them. We studied 2,462 blood donors classified as Caucasian, Mulattos e Blacks according to their anthropological characteristics as well as to their ancestry information. Phenotype frequencies were studied in the ABO, MNS, P, Rh, Lutheran, Kell, Lewis, Duffy e Kidd blood group systems. We did not find significant statistically difference between Blacks and Mulattos

  1. Efeitos da farinha de folhas de mandioca sobre a peroxidação lipídica, o perfil lipídico sangüíneo e o peso do fígado de ratos Effects of cassava leaf flour on lipidic peroxidation, blood lipidic profile and liver weight of rats

    Directory of Open Access Journals (Sweden)

    Daniela Séfora de Melo

    2007-04-01

    Full Text Available Sabe-se que polifenóis e saponinas apresentam efeitos antioxidante e hipolipidêmico, respectivamente. Como folhas de mandioca contêm estas substâncias, foi investigado o efeito de dietas contendo a farinha de folhas de mandioca (FFM sobre a peroxidação lipídica, o perfil lipídico sangüíneo e o peso do fígado de ratos. Para isto, folhas maduras de mandioca (Manihot esculenta Crantz cv. Cacao foram secas em estufa ventilada a 30-35 ºC e trituradas sem os pecíolos. Um ensaio biológico, com 32 ratos machos Wistar, foi conduzido por um período de 7 semanas com quatro tratamentos: dieta controle e dietas contendo 5%, 10% e 15% de FFM, sendo todas suplementadas com 1% de colesterol. As dietas se apresentaram isoenergéticas e contendo os mesmos níveis de proteína digestível e fibras. Foi observado que dietas contendo FFM não apresentaram efeitos significativos sobre o perfil lipídico sangüíneo e sobre as variáveis de desempenho, mas contribuiram para o aumento no peso do fígado. Já as dietas contendo 10% e 15% de FFM foram associadas à redução nos teores plasmáticos de substâncias reativas ao ácido tiobarbitúrico.It is well known that polyphenols and saponins present antioxidant and hypolipidemic effects, respectively. As cassava leaves contains these substances, the effects of diets supplemented with cassava leaf flour (CLF on lipidic peroxidation, blood lipid profile and liver weight of rats were investigated. Therefore, ripe cassava leaves (Manihot esculenta Crantz cv. Cacao were dried in a ventilated oven at 30-35 ºC and ground without the petioles. A biological assay was conducted during 7 weeks with 32 Wistar male rats submitted to four treatments: control diet and diets containing 5%, 10% and 15% CLF, all supplemented with 1% cholesterol. Diets were isoenergetic and contained the same levels of digestible protein, and fibers. It was observed that diets containing CLF presented no significant effect on blood

  2. Crescimento de Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae sob diferentes níveis de sombreamento Growth of Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae under different shading levels

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    Ana Lúcia da Silva Lima

    2010-03-01

    Full Text Available Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. é uma espécie clímax tolerante a sombra, ao passo que Enterolobium contortisiliquum (Vell. Morong. é uma espécie pioneira. O desenvolvimento destas espécies pode refletir a habilidade de adaptação aos diferentes fatores ambientais (luz, água e temperatura no local em que estão crescendo. O suprimento inadequado de um desses fatores pode reduzir o vigor da planta e limitar seu desenvolvimento. O presente trabalho teve como objetivo avaliar os efeitos do nível de sombreamento no crescimento e a concentração de pigmentos fotossintéticos em duas espécies de leguminosas arbóreas, Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong. O experimento foi conduzido no Setor de Olericultura do Centro Universitário Luterano de Ji-Paraná (CEULJI/ULBRA/Rondônia. Durante a formação das mudas, ambas as espécies foram expostas a quatro tratamentos de sombra: 0 % (controle - sol pleno; 30 %; 50 % e 80 %. Cada tratamento foi constituído com três repetições de cada espécie; o delineamento experimental foi inteiramente casualisado. Quatro meses após a semeadura, as seguintes análises foram realizadas: número de folhas, altura da planta, comprimento do sistema radicular, massa seca total e concentração de pigmentos fotossintéticos. O tratamento sob sol pleno afetou negativamente o crescimento de ambas as espécies. As mudas crescidas sob 50% e 80% apresentaram melhor desenvolvimento. Conforme o aumento do sombreamento houve um decréscimo na razão clorofila a/b e um aumento nas concentrações de clorofila total e carotenóides totais.Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. is a clímax shadow tolerant specie and Enterolobium contortisiliquum (Vell. Morong., by the other hand, is considered as a pioneer specie. The development of these species may reflect its adaptation ability to different environmental

  3. The effectiveness of Lee Silverman Voice Treatment therapy issued interactively through an iPad device: A non-inferiority study.

    Science.gov (United States)

    Griffin, Murray; Bentley, John; Shanks, Joseph; Wood, Carly

    2018-04-01

    Introduction This study compared the differences in recorded speech variables between people treated with conventional 'in person' Lee Silverman Voice Treatment (LSVT) and those treated remotely via iPad-based 'Facetime'. Method Eight participants were selected for the iPad LSVT, and 21 similarly matched subjects were selected from existing data to form the 'in person' group. Participants in both groups had diagnosed idiopathic Parkinson's disease and moderate hypokinetic dysarthria. Eighteen sessions of prescribed LSVT comprising a pre-treatment assessment, 16 treatment sessions, and a six months' post-treatment assessment were administered for each person. In both groups, pre- and post-treatment assessments were conducted face-to-face. Performance measures were recorded during assessment and treatment. Average measures were determined for all tasks at all time points and a summary outcome variable was composed from across-task performance. Results Non-inferiority testing confirmed that iPad LSVT was non-inferior in treating all LSVT task 3 variables except generating words, with the 90% upper confidence intervals (CI) lying between the non-inferiority margin of ± 2.25 and zero. The iPad was superior in treating the task 3 rainbow reading passage and describing motor task variables with upper and lower 90% CI values being negative. The improvement in the summary outcome variable score was also superior in the iPad group. Discussion Non-inferiority testing implies that the iPad LSVT is non-inferior in treating task three variables when compared to traditional LSVT. The study supports further development of remote delivery solutions involving the Apple iPad and 'Facetime' system as a means of improving access to services and the participant's experience.

  4. Use of Antibody Responses against Locus of Enterocyte Effacement (LEE)-Encoded Antigens To Monitor Enterohemorrhagic Escherichia coli Infections on Cattle Farms

    Science.gov (United States)

    Joris, Maria-Adelheid; Vanrompay, Daisy; Verstraete, Karen; De Reu, Koen; De Zutter, Lieven

    2013-01-01

    Enterohemorrhagic Escherichia coli (EHEC) is a significant zoonotic pathogen causing severe disease associated with watery and bloody diarrhea, hemorrhagic colitis, and the hemolytic-uremic syndrome (HUS) in humans. Infections are frequently associated with contact with EHEC-contaminated ruminant feces. Both natural and experimental infection of cattle induces serum antibodies against the LEE-encoded proteins intimin, EspA, EspB, and Tir and the Shiga toxins Stx1 and Stx2, although the latter are poorly immunogenic in cattle. We determined whether antibodies and/or the kinetics of antibody responses against intimin, Tir, EspA, and/or EspB can be used for monitoring EHEC infections in beef cattle herds in order to reduce carcass contamination at slaughter. We examined the presence of serum antibodies against recombinant O157:H7 E. coli intimin EspA, EspB, and Tir during a cross-sectional study on 12 cattle farms and during a longitudinal time course study on two EHEC-positive cattle farms. We searched for a possible correlation between intimin, Tir, EspA, and/or EspB antibodies and fecal excretion of EHEC O157, O145, O111, O103, or O26 seropathotypes. The results indicated that serum antibody responses to EspB and EspA might be useful for first-line screening at the herd level for EHEC O157, O26, and most likely also for EHEC O103 infections. However, antibody responses against EspB are of less use for monitoring individual animals, since some EHEC-shedding animals did not show antibody responses and since serum antibody responses against EspB could persist for several months even when shedding had ceased. PMID:23563950

  5. Age and growth of European barbel Barbus barbus (Cyprinidae in the small, mesotrophic River Lee and relative to other populations in England

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    Vilizzi L.

    2013-08-01

    Full Text Available Suspected of being in decline, the European barbel Barbus barbus population of the River Lee, a heavily-modified river in South East England, has been the subject of investigations to identify factors associated with perceived population decreases. Population surveys between 1995 and 1999 captured a total of 912 individuals, and standard length (SL frequency analyses between years suggested that the population decline was not related to juvenile recruitment but rather to a recruitment bottleneck in fish 300–340 mm SL. This bottleneck probably results from insufficient available habitat suitable to this size class. Of the sampled fish, scales were removed from 764 and were used in a scale ageing exercise among three researchers. Analyses of their independent age estimates revealed variable interpretations, which arose from uncertainties relating to the difficulty of analysing scale patterns from relatively large, slow-growing fish. Nevertheless, error was within published acceptable margins, and age estimates revealed B. barbus in the river to age 10 years, lower than in many UK rivers. The SL-at-age growth curve was characterised by very fast growth in the initial years of life. Thus, the causal factors in the decline of this B. barbus population appear to have been in the adult life-stage habitat and were likely related to the loss of longitudinal connectivity, mainly due to the presence of water retention structures. River and aquatic ecosystem remediation strategies should therefore focus on enhancing longitudinal connectivity in conjunction with the ongoing improvement of water quality and ecosystem integrity.

  6. Long-term effects of Lee Silverman Voice Treatment on daily voice use in Parkinson's disease as measured with a portable voice accumulator.

    Science.gov (United States)

    Körner Gustafsson, Joakim; Södersten, Maria; Ternström, Sten; Schalling, Ellika

    2018-02-15

    This study examines the effects of an intensive voice treatment focusing on increasing voice intensity, LSVT LOUD ® Lee Silverman Voice Treatment, on voice use in daily life in a participant with Parkinson's disease, using a portable voice accumulator, the VoxLog. A secondary aim was to compare voice use between the participant and a matched healthy control. Participants were an individual with Parkinson's disease and his healthy monozygotic twin. Voice use was registered with the VoxLog during 9 weeks for the individual with Parkinson's disease and 2 weeks for the control. This included baseline registrations for both participants, 4 weeks during LSVT LOUD for the individual with Parkinson's disease and 1 week after treatment for both participants. For the participant with Parkinson's disease, follow-up registrations at 3, 6, and 12 months post-treatment were made. The individual with Parkinson's disease increased voice intensity during registrations in daily life with 4.1 dB post-treatment and 1.4 dB at 1-year follow-up compared to before treatment. When monitored during laboratory recordings an increase of 5.6 dB was seen post-treatment and 3.8 dB at 1-year follow-up. Changes in voice intensity were interpreted as a treatment effect as no significant correlations between changes in voice intensity and background noise were found for the individual with Parkinson's disease. The increase in voice intensity in a laboratory setting was comparable to findings previously reported following LSVT LOUD. The increase registered using ambulatory monitoring in daily life was lower but still reflecting a clinically relevant change.

  7. HYDRAULICS, LEE COUNTY, GEORGIA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  8. Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

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    Jang K

    2017-03-01

    Full Text Available Kyungho Jang,1,2,* Min-Kyoung Kim,3,4,* Jaeseong Oh,1 SeungHwan Lee,1 Joo-Youn Cho,1 Kyung-Sang Yu,1 Tai Kiu Choi,3 Sang-Hyuk Lee,3,4 Kyoung Soo Lim4 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Center for Clinical Pharmacology and Biomedical Research Institute, Chonbuk National University Medical School, Jeonju, 3Department of Psychiatry, 4Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine and CHA Bundang Medical Center, Seongnam, Republic of Korea *These authors contributed equally to this work Purpose: Oseltamivir is widely used in the treatment and prophylaxis of influenza A and B viral infections. It is ingested as an oral prodrug that is rapidly metabolized by carboxylesterase 1 (CES1 to its active form, oseltamivir carboxylate. Dexamethasone is also used in the treatment of acute respiratory distress syndrome, a severe complication of influenza; however, its influence on the pharmacokinetics (PK of oseltamivir is controversial. The aim of this study was to investigate the effects of coadministering oseltamivir and dexamethasone on the PK of oseltamivir in healthy volunteers. Methods: An open-label, two-period, one-sequence, multiple-dose study was conducted in 19 healthy male volunteers. Oseltamivir (75 mg was orally administered on Day 1 and Day 8, and dexamethasone (1.5 mg was administered once daily from Day 3 to Day 8. Serial blood and urine samples were collected for PK analysis of oseltamivir and oseltamivir carboxylate on Day 1 and Day 8. Oseltamivir and oseltamivir carboxylate concentrations in plasma and urine were determined using liquid chromatography–tandem mass spectrometry. Results: Area under the plasma concentration–time curve (AUC of oseltamivir and oseltamivir carboxylate decreased after dexamethasone treatment for 6 days. The geometric mean ratio (90% confidence interval of the metabolic ratio

  9. Lee Silverman Voice Treatment versus standard speech and language therapy versus control in Parkinson's disease: a pilot randomised controlled trial (PD COMM pilot).

    Science.gov (United States)

    Sackley, Catherine M; Smith, Christina H; Rick, Caroline E; Brady, Marian C; Ives, Natalie; Patel, Smitaa; Woolley, Rebecca; Dowling, Francis; Patel, Ramilla; Roberts, Helen; Jowett, Sue; Wheatley, Keith; Kelly, Debbie; Sands, Gina; Clarke, Carl E

    2018-01-01

    Speech-related problems are common in Parkinson's disease (PD), but there is little evidence for the effectiveness of standard speech and language therapy (SLT) or Lee Silverman Voice Treatment (LSVT LOUD®). The PD COMM pilot was a three-arm, assessor-blinded, randomised controlled trial (RCT) of LSVT LOUD®, SLT and no intervention (1:1:1 ratio) to assess the feasibility and to inform the design of a full-scale RCT. Non-demented patients with idiopathic PD and speech problems and no SLT for speech problems in the past 2 years were eligible. LSVT LOUD® is a standardised regime (16 sessions over 4 weeks). SLT comprised individualised content per local practice (typically weekly sessions for 6-8 weeks). Outcomes included recruitment and retention, treatment adherence, and data completeness. Outcome data collected at baseline, 3, 6, and 12 months included patient-reported voice and quality of life measures, resource use, and assessor-rated speech recordings. Eighty-nine patients were randomised with 90% in the therapy groups and 100% in the control group completing the trial. The response rate for Voice Handicap Index (VHI) in each arm was ≥ 90% at all time-points. VHI was highly correlated with the other speech-related outcome measures. There was a trend to improvement in VHI with LSVT LOUD® (difference at 3 months compared with control: - 12.5 points; 95% CI - 26.2, 1.2) and SLT (difference at 3 months compared with control: - 9.8 points; 95% CI - 23.2, 3.7) which needs to be confirmed in an adequately powered trial. Randomisation to a three-arm trial of speech therapy including a no intervention control is feasible and acceptable. Compliance with both interventions was good. VHI and other patient-reported outcomes were relevant measures and provided data to inform the sample size for a substantive trial. International Standard Randomised Controlled Trial Number Register: ISRCTN75223808. registered 22 March 2012.

  10. "¿Entiendes, con seguridad, lo que lees?" Hch 8, 30 Caminos de la hermenéutica de [en] la Escritura

    Directory of Open Access Journals (Sweden)

    Ignacio Chuecas Saldías

    2005-01-01

    Full Text Available El presente artículo busca ser una contribución para una hermenéutica bíblica práctica: es decir, no mira hacia la teoría de la interpretación, sino más bien hacia la praxis actual, especialmente en el campo de los estudios sincrónicos. Al mismo tiempo, pretende invitar al lector a conocer los métodos hermenéuticos propios de la tradición del Nuevo Testamento. Es a través de los caminos del midrash judeocristiano que nos acercamos a la praxis hermenéutica de los escritores bíblicos. El objetivo propuesto es llevado a cabo empleando como guía hermenéutica, a la vez que como laboratorio donde se ejemplifican los principios expuestos, el texto bíblico del encuentro del evangelista Felipe y el ministro de la reina de Etiopía (Hechos 8, 20-40. La pregunta de Felipe sirve de leitmotiv a este proceso: ¿entiendes, con certeza, lo que lees? Hermenéutica bíblica es siempre una manera de leer donde la escritura se interpreta a sí misma. El artículo presta especial atención a las categorías y herramientas de interpretación que se han desarrollado a partir de las nuevas impostaciones literarias en el campo de la exégesis bíblicaThe article attempts to make a contribution to the practical biblical hermeneutics focusing on the actual praxis, especially exploring the field of synchronic studies, rather than on the theory of interpretation. It also aims at offering an insight to the hermeneutic methods of the New Testament tradition, approaching the hermeneutic praxis of the biblical writers through the judeo-christian midrash paths. The accomplish such an objective, the author focuses on the biblical text of Philip's encounter with the minister of the queen of Ethiopia (Acts, 8, 20-40 as the hermeneutic guide and source to illustrate the principles being exposed. Philip's question "Can you really understand what you are reading?" serves as leitmotif to this process, as the biblical hermeneutics is a way of reading inwhich the

  11. Waste Conversion into n-Caprylate and n-Caproate: Resource Recovery from Wine Lees Using Anaerobic Reactor Microbiomes and In-line Extraction.

    Science.gov (United States)

    Kucek, Leo A; Xu, Jiajie; Nguyen, Mytien; Angenent, Largus T

    2016-01-01

    To convert wastes into sustainable liquid fuels and chemicals, new resource recovery technologies are required. Chain elongation is a carboxylate-platform bioprocess that converts short-chain carboxylates (SCCs) (e.g., acetate [C2] and n-butyrate [C4]) into medium-chain carboxylates (MCCs) (e.g., n-caprylate [C8] and n-caproate [C6]) with hydrogen gas as a side product. Ethanol or another electron donor (e.g., lactate, carbohydrate) is required. Competitive MCC productivities, yields (product vs. substrate fed), and specificities (product vs. all products) were only achieved previously from an organic waste material when exogenous ethanol had been added. Here, we converted a real organic waste, which inherently contains ethanol, into MCCs with n-caprylate as the target product. We used wine lees, which consisted primarily of settled yeast cells and ethanol from wine fermentation, and produced MCCs with a reactor microbiome. We operated the bioreactor at a pH of 5.2 and with continuous in-line extraction and achieved a MCC productivity of 3.9 g COD/L-d at an organic loading rate of 5.8 g COD/L-d, resulting in a promising MCC yield of 67% and specificities of 36% for each n-caprylate and n-caproate (72% for both). Compared to all other studies that used complex organic substrates, we achieved the highest n-caprylate-to-ncaproate product ratio of 1.0 (COD basis), because we used increased broth-recycle rates through the forward membrane contactor, which improved in-line extraction rates. Increased recycle rates also allowed us to achieve the highest reported MCC production flux per membrane surface area thus far (20.1 g COD/m 2 -d). Through microbial community analyses, we determined that an operational taxonomic unit (OTU) for Bacteroides spp. was dominant and was positively correlated with increased MCC productivities. Our data also suggested that the microbiome may have been shaped for improved MCC production by the high broth-recycle rates. Comparable abiotic

  12. Waste conversion into n-caprylate and n-caproate: resource recovery from wine lees using anaerobic reactor microbiomes and in-line extraction

    Directory of Open Access Journals (Sweden)

    Leo A. Kucek

    2016-11-01

    Full Text Available To convert wastes into sustainable liquid fuels and chemicals, new resource recovery technologies are required. Chain elongation is a carboxylate-platform bioprocess that converts short-chain carboxylates (SCCs (e.g., acetate C2 and n-butyrate C4 into medium-chain carboxylates (MCCs (e.g., n-caprylate C8 and n-caproate C6 with hydrogen gas as a side product. Ethanol or another electron donor (e.g., lactate, carbohydrate is required. Competitive MCC productivities, yields (product vs. substrate fed, and specificities (product vs. all products were only achieved previously from an organic waste material when exogenous ethanol had been added. Here, we converted a real organic waste, which inherently comprised of ethanol, into MCCs with n-caprylate as the target product. We used wine lees, which consisted primarily of settled yeast cells and ethanol from wine fermentation, and produced MCCs with a reactor microbiome. We operated the bioreactor at a pH of 5.2 and with continuous in-line extraction and achieved a MCC productivity of 3.9 g COD/L-d at an organic loading rate of 5.8 g COD/L-d, resulting in a promising MCC yield of 67% and specificities of 36% for each n-caprylate and n-caproate (72% for both. Compared to all other studies that used complex organic substrates, we achieved the highest n-caprylate-to-n-caproate product ratio of 1.0 (COD basis, because we used increased broth-recycle rates through the forward membrane contactor, which improved in-line extraction rates. Increased recycle rates also allowed us to achieve the highest reported MCC production flux per membrane surface area thus far (20.1 g COD/m2-d. Through microbial community analyses, we determined that an operational taxonomic unit (OTU for Bacteroides spp. was dominant and was positively correlated with increased MCC productivities. Our data also suggested that the microbiome may have been shaped for improved MCC production by the high broth-recycle rates. Comparable abiotic

  13. Status and trends of the rainbow trout population in the Lees Ferry reach of the Colorado River downstream from Glen Canyon Dam, Arizona, 1991–2009

    Science.gov (United States)

    Makinster, Andrew S.; Persons, William R.; Avery, Luke A.

    2011-01-01

    The Lees Ferry reach of the Colorado River, a 25-kilometer segment of river located immediately downstream from Glen Canyon Dam, has contained a nonnative rainbow trout (Oncorhynchus mykiss) sport fishery since it was first stocked in 1964. The fishery has evolved over time in response to changes in dam operations and fish management. Long-term monitoring of the rainbow trout population downstream of Glen Canyon Dam is an essential component of the Glen Canyon Dam Adaptive Management Program. A standardized sampling design was implemented in 1991 and has changed several times in response to independent, external scientific-review recommendations and budget constraints. Population metrics (catch per unit effort, proportional stock density, and relative condition) were estimated from 1991 to 2009 by combining data collected at fixed sampling sites during this time period and at random sampling sites from 2002 to 2009. The validity of combining population metrics for data collected at fixed and random sites was confirmed by a one-way analysis of variance by fish-length class size. Analysis of the rainbow trout population metrics from 1991 to 2009 showed that the abundance of rainbow trout increased from 1991 to 1997, following implementation of a more steady flow regime, but declined from about 2000 to 2007. Abundance in 2008 and 2009 was high compared to previous years, which was likely the result of increased early survival caused by improved habitat conditions following the 2008 high-flow experiment at Glen Canyon Dam. Proportional stock density declined between 1991 and 2006, reflecting increased natural reproduction and large numbers of small fish in samples. Since 2001, the proportional stock density has been relatively stable. Relative condition varied with size class of rainbow trout but has been relatively stable since 1991 for fish smaller than 152 millimeters (mm), except for a substantial decrease in 2009. Relative condition was more variable for larger

  14. Revascularização miocárdica com enxerto composto de artéria torácica interna esquerda em Y: análise de fluxo sangüíneo Myocardial revascularization surgery using composite Y-graft of the left internal thoracic artery: blood flow analysis

    Directory of Open Access Journals (Sweden)

    José Glauco Lobo Filho

    2004-03-01

    Full Text Available OBJETIVO: Verificar o comportamento do fluxo sangüíneo na artéria torácica interna esquerda (ATIE, quando utilizada para revascularizar a artéria interventricular anterior (AIA e mais um ramo do sistema coronariano esquerdo (SCE. MÉTODO: No presente estudo, compara-se o fluxo obtido pela ecocardiografia Doppler na ATIE, em repouso e sob estresse com dobutamina, em dois grupos de 20 pacientes cada. No grupo A, foi utilizado enxerto pediculado de ATIE anastomosada unicamente à AIA. No grupo B, a ATIE revasculariza a AIA, e um enxerto de veia safena magna, anastomosado em "Y" à ATIE, revasculariza outro ramo do SCE. O estudo angiográfico demonstrou patência de todos os enxertos em ambos os grupos. Na avaliação pela ecocardiografia Doppler foram realizadas as seguintes medidas: débitos sistólico (DS, diastólico e total, razão entre o débito total em estresse pelo débito total em repouso (DTE/DTR, velocidades de pico sistólico (VPS e diastólico e razão entre essas velocidades. RESULTADOS: Todos os parâmetros analisados apresentaram diferença estatisticamente significativa, com exceção do DS, DTE/DTR e VPS. CONCLUSÃO: Nas condições e métodos usados neste estudo, pode-se inferir que o fluxo sangüíneo na ATIE no enxerto composto (Grupo B é maior que no enxerto simples (Grupo A, o que demonstra a grande capacidade da ATIE em adaptar-se à demanda de fluxo.OBJECTIVE: To assess the left internal thoracic artery (LITA flow pattern, when it was used to supply the left anterior descending artery (LADA and another branch from the left coronary artery system (LCAS. METHODS: In the following study, the left internal thoracic artery flow was investigated by echocardiography Doppler, at rest and under dobutamine stress, in two twenty-patient groups. Group A consisted of patients who received only a pedicled LITA graft to the LADA. Group B consisted of patients who received a pedicled LITA graft associated with a vein graft to supply

  15. Efeitos das cardioplegias sangüíneas hipotérmica e normotérmica nos substratos intracelulares em pacientes com corações hipertróficos The effect of cold and warm blood cardioplegia on intracellular substrates in patients with hypertrophic hearts

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    Walter J. GOMES

    2000-06-01

    Full Text Available OBJETIVOS: As cardioplegias sangüíneas normotérmica e hipotérmica, administradas de maneira anterógrada e intermitente, têm demonstrado serem eficientes na proteção miocárdica em cirurgias de revascularização miocárdica. Entretanto, pouco se conhece da eficiência dessas técnicas em corações hipertróficos. Dessa maneira, foram estudados seus efeitos nos substratos intracelulares miocárdicos em pacientes portadores de estenose aórtica, submetidos a cirurgia de troca valvar aórtica. CASUÍSTICA E MÉTODOS: A concentração intracelular miocárdica dos substratos (ATP, lactato, glutamato, aspartato e alanina foi medida em biópsias de ventrículo esquerdo de 20 pacientes submetidos a troca valvar aórtica, usando, como método de proteção miocárdica, cardioplegia sangüínea normotérmica (n=10 ou hipotérmica (n=10, administradas de forma anterógrada e intermitente. As biópsias foram retiradas 5 minutos após o início da circulação extracorpórea (controle, 30 minutos após o pinçamento aórtico (isquemia e 20 minutos após o despinçamento (reperfusão. RESULTADOS: Não houve alterações significantes na concentração intracelular dos substratos nas amostras coletadas durante o período isquêmico, em comparação ao controle. Na reperfusão, entretanto, houve significante queda nos valores de ATP e aminoácidos em ambos os grupos, em relação ao grupo controle. CONCLUSÃO: Os dados sugerem que ambos os protocolos de proteção miocárdica empregados não foram eficientes na proteção miocárdica de corações hipertróficos.OBJECTIVE: Warm intermittent blood cardioplegia has been shown to prevent the reperfusion damage seen when cold blood cardioplegia is used in patients undergoing coronary revascularization. Little is known on the effects of these two cardioplegic techniques on hypertrophic hearts. The aim of this study was to investigate the comparative effects of cold and warm antegrade blood cardioplegia in

  16. Influência da terapia com espironolactona sobre níveis sangüíneos de tiamina em pacientes com insuficiência cardíaca Influence of spironolactone therapy on thiamine blood levels in patients with heart failure

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    Ricardo Mourilhe Rocha

    2008-05-01

    Full Text Available FUNDAMENTO: Estudos do manejo não-farmacológico da insuficiência cardíaca (IC têm sido muito escassos. A importância de micronutrientes como tiamina há muito é conhecida, uma vez que sua deficiência está associada com o desenvolvimento de IC de alto débito. OBJETIVO: Nós estudamos a relação entre adicionar à inibição da ECA uma supressão adicional da aldosterona com espironolactona e níveis sangüíneos de tiamina (pmol/ml. MÉTODOS: Um total de 22 pacientes (pc com IC (classes III/IV da NYHA foi dividido em dois grupos [grupo I - espironolactona 25mg/dia (n=11 e grupo II - sem espironolactona (n=11]. Determinamos os níveis de tiamina pelo uso da atividade da transcetolase eritrocitária. Os grupos foram comparados com relação à ingesta alimentar, demografia, doses de furosemida e níveis sangüíneos de tiamina, usando os testes de Mann-Whitney e t de Student. Analisamos as proporções com testes de qui-quadrado e de Kruskal-Wallis para associarmos a tiamina com fatores demográficos e usamos as doses de furosemida como variáveis dependentes. RESULTADOS: Os grupos I e II eram similares em relação à ingesta alimentar, doses diárias de furosemida (110,9±30,2 e 105,5±26,9 mg, respectivamente; p>0,05, demografia (etiologia, idade, hipertensão, diabete, tabagismo, abuso de álcool, dislipidemia e tratamento adjuvante da IC com drogas. Os pacientes do grupo I mostraram níveis de tiamina significativamente superiores, comparados com aqueles do grupo II (277,2±89,8 e 154,7±35,7, respectivamente (pBACKGROUND: The nonpharmacological management of heart failure (HF has been understudied. The importance of micronutrients such as thiamine has long been known since its deficiency is associated with the development of high-output HF. OBJECTIVE: We studied the relationship between adding to ACE inhibition further aldosterone suppression with spironolactone and thiamine blood levels (pmol/ml. METHODS: A total of 22 patients

  17. Produção e composição do leite, metabólitos sangüíneos e concentração hormonal de cabras lactantes da raça Toggenburg tratadas com somatotropina bovina recombinante

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    Amorim Elenice Andrade Moraes e

    2006-01-01

    Full Text Available Estudou-se a influência da aplicação de somatotropina bovina recombinante sobre a produção e composição do leite, os metabólicos sangüíneos e a concentração hormonal em cabras no terço médio da lactação. Foram utilizadas 24 cabras da raça Toggenburg, divididas em dois tratamentos: T1 (n=12: aplicação de 250 mg de r-bST a cada 14 dias, em um total de quatro aplicações; e T2 (n=12: aplicação de solução salina (controle. O tratamento com r-bST não aumentou a produção de leite e não influenciou os teores de gordura, proteína e extrato seco. A porcentagem de lactose no leite foi maior (4,47 ? 0,2 para T1 versus 4,34 ? 0,2% para T2 e a contagem de células somáticas menor nos animais tratados em relação aos controle (681,1 ? 689,9 para T1 versus 1.001,84 ? 610,9 [x10³ células/mL] para T2. A administração de r-bST aumentou as concentrações séricas de ácidos graxos não-esterificados de T2 (309,67 ? 169,62 x 247,34 ? 126,38 mEq/L, para T1 e T2, respectivamente e reduziu as concentrações de uréia (86,84 ? 33,81 x 121,16 ? 42,57 mg/dL, para T1 e T2 respectivamente. A r-bST reduziu as concentrações de colesterol total e HDL (82,46 ? 19,25 x 89,29 ? 23,66 mg/dL e 155,95 ? 19,67 x 177,67 ? 32,79 mg/dL, para T1 e T2 respectivamente, enquanto as concentrações de albumina, glicose, proteínas totais, beta-hidroxibutirato e tiroxina não foram influenciadas pela r-bST, que também não influenciou o peso e o escore corporal dos animais. A r-bST aumentou os teores de lactose, reduziu a contagem de células somáticas e promoveu alterações nos metabólicos sangüíneos e no leite de cabras lactantes.

  18. Efeitos do bloqueio pudendo, peridural e subaracnóideo sobre a coagulação sangüínea de gestantes Efectos del bloqueo pudendo, peridural y subaracnoideo sobre la coagulación sanguínea de embarazadas Effects of pudendal nerve, epidural and subarachnoid block on coagulation of pregnant women

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    Alberto Vasconcelos

    2008-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Tem sido atribuída à anestesia regional diminuição significativa das complicações tromboembólicas no pós-operatório, provavelmente por sua ação atenuadora sobre a resposta neuroendócrino-metabólica. As gestantes, que apresentam aumento importante da coagulabilidade sangüínea, podem, teoricamente, beneficiar-se desse efeito por ocasião do parto. O objetivo deste estudo foi verificar o efeito da anestesia regional sobre a coagulação sangüínea em gestantes. MÉTODO: Foram estudadas 30 pacientes no terceiro trimestre de gestação, sendo dez submetidas à anestesia peridural para cesariana, com 150 mg de bupivacaína a 0,5% sem epinefrina e 2 mg de morfina (grupo PD; dez à anestesia subaracnóidea para cesariana com 15 mg de bupivacaína hiperbárica a 0,5% e 0,2 mg de morfina (grupo SA; e dez a bloqueio de pudendo para parto vaginal, com doses de até 100 mg de bupivacaína a 0,5% sem epinefrina (grupo BP. A coagulação sangüínea foi avaliada por meio de coagulograma (tempo de protrombina, tempo de trombina, tempo de tromboplastina parcial ativada e de tromboelastograma (tempo r, tempo k, tempo r + k, ângulo alfa e amplitude máxima nos seguintes momentos: antes e após a anestesia, após o nascimento do feto e 24 horas após a anestesia nos grupos PD e SA. No grupo BP a avaliação foi realizada antes da anestesia, após o nascimento do feto e 24 horas após a anestesia. RESULTADOS: Os resultados mostraram que nenhuma das técnicas anestésicas utilizadas teve influência na coagulação sangüínea das gestantes. Demonstraram, também, que durante o trabalho de parto tem início um processo de ativação da coagulação que é responsável pelas alterações encontradas nos três grupos estudados. CONCLUSÕES: Nas condições do presente estudo o bloqueio simpático e o anestésico local não influíram sobre a coagulação em gestantes de termo submetidas à anestesia peridural, subaracn

  19. Eesti luuletaja päris oma prantsuse luuleraamat. August Sanga, Jaan Krossi ja Ain Kaalepi loomingust 1960. aastail / An Estonian Poet’s Own Book of French Poetry. About the Works of August Sang, Jaan Kross and Ain Kaalep in the 1960s

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    Katre Talviste

    2013-12-01

    Full Text Available This article positions the translations of French verse works (plays and selected collections of individual poets that August Sang, Jaan Kross and Ain Kaalep made in the 1960s, onto the background of their own original works. At that time, August Sang translated four plays by Molière (The Misanthrope, Tartuffe, The School for Wives in 1961; Amphitryon in 1961, which have already been discussed in relation to the tradition of translating the French syllabic verse into Estonian, because these translations form a considerable part of the body of Estonian translations of French verse poetry. For Jaan Kross and Ain Kaalep, the wider context is created by the so-called free verse battles in the 1950s, to which we can link Kross’ translation of a selected collection of Éluard (Veel enne kostma peab, 1969 and Kaalep’s translation of a selected collection of Prévert (Kuidas portreteerida lindu, 1965. One of the two remaining translations by Kross, (Rostand’s Cyrano de Bergerac, 1964, can also be examined in relation to the problems of translating verse, but the other, (Béranger’s Laulud, 1963, should be discussed in the framework of intellectual and cultural resistance, a part of which was also the struggle put up for the existence of free verse in the 1950s and 1960s. Of August Sang’s original work, the article examines his collection of poems Võileib suudlusega (1963, written simultaneously with his translations of Molière’s plays and published right after them. Both the translations and the collection of original poems have attracted critics’ attention with their remarkable lack of linguistic constraint and simplicity. Although Sang has rarely voiced theoretical ideas about translation or explained his method, both his poetic image, outlined in the collection Võileib suudlusega, and his search for right words, reflected in the drafts of his translations, let us believe that the simplicity of expression and the avoidance of marked

  20. Margem de segurança do meloxicam em cães: efeitos deletérios nas células sangüíneas e trato gastrintestinal Margin of safety of meloxicam in dogs: deleterious effects on blood cells and gastrointestinal tract

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    Marilac Maria Arnaldo Alencar

    2003-06-01

    Full Text Available Este trabalho investigou a margem de segurança do inibidor COX-2, meloxicam, em cães, enfocando seus efeitos deletérios nas células sangüíneas e no trato gastrintestinal. Para tanto, após uma avaliação clínico-laboratorial, os cães foram distribuídos nos seguintes grupos: I (placebo; n= 3, II (piroxicam; 1,0mg kg-1; n= 5, III (meloxicam; 0,2mg kg-1; n= 5, IV (meloxicam;1,0mg kg-1; n= 5 e V (meloxicam; 2,0mg kg-1; n= 5. Os fármacos foram usados, por via oral, por 16 dias. No 17º dia, repetiu-se o hemograma completo e, então, procedeu-se a eutanásia seguida pela necrópsia. No grupo I, não houve alterações dignas de nota. No grupo II, todos os cães apresentaram episódios moderados de vômito e diarréia. O perfil celular sangüíneo não foi significativamente modificado. Em dois cães, houve redução no hematócrito e na hemoglobina. Na necropsia, observaram-se focos hemorrágicos e lesões gastriduodenais moderadas. A análise microscópica revelou a presença de gastrite e enterite ulcerativa. No grupo III, quatro cães (80% apresentaram vômito e diarréia, sem alteração no perfil celular sangüíneo. Na análise macroscópica, observaram-se lesões brandas na mucosa gástrica e focos hemorrágicos no duodeno em quatro cães. Na histopatologia, observaram-se lesões sugestivas de discreta gastroenterite. No grupo IV, os cinco cães tiveram vômito e diarréia sanguinolenta. Quatro deles (80% apresentaram anemia (p This study investigated the margin of safety of the COX-2e inhibitor, meloxicam on blood cells and gastrointestinal tract of dogs. After a clinical and laboratorial examination, the dogs were distributed in the following groups: I (placebo; n=3, II (piroxicam: 1.0mg kg-1; n=5, III (meloxicam: 0.2mg kg-1; n=5, IV (meloxican: 1.0mg kg-1; n=5 and V (meloxican: 2.0mg kg-1; n=5. The drugs were given orally for 16 days. On the 17th day the complete hemogram was repeated and the euthanasia and necropsy were then

  1. O ENSINO DE MATEMÁTICA NOS ANOS INICIAIS DO ENSINO FUNDAMENTAL: O PROBLEMA DA FORMAÇÃO DO PROFESSOR E AS CONTRIBUIÇÕES DE LEE SHULMAN E DE V. V. DAVYDOV

    OpenAIRE

    Ferreira, Valdivina Alves; Freitas, Raquel Aparecida Marra da Madeira

    2014-01-01

    O objetivo deste texto é apresentar uma discussão crítica acerca da formação do professor que ensina matemática nos anos iniciais do Ensino Fundamental. Inicia-se pelo delineamento do problema das dificuldades de ensino e de aprendizagem de matemática, recorrentes nas pesquisas e nos discursos acadêmicos, destacando como um dos fatores a formação dos professores. Em seguida apresentam-se as contribuições de dois teóricos distintos, Lee Shulman e V. V Davydov, para o enfrentamento deste proble...

  2. MODIFICAÇÃO DO MÉTODO LEE SILVERMAN DE TRATAMENTO VOCAL NA DOENÇA DE PARKINSON: ANÁLISE PERCEPTIVO-AUDITIVA E ACÚSTICA COMPUTADORIZADA

    OpenAIRE

    Barros, Andréa Lopes de Souza Miranda de

    2006-01-01

    OBJETIVO: verificar a aplicabilidade do Lee Silverman Voice Treatment® numa freqüência diferenciada, em indivíduos portadores de DP, por meio de análise perceptivo-auditiva e acústica computadorizada vocal. PACIENTES E MÉTODO: o estudo foi realizado com 12 indivíduos portadores da DP classificados entre os graus 1 e 4 (escala Hoehn & Yahr), com queixas fonoaudiológicas, submetidos à modificação do LSVT® com aplicação em freqüência de duas vezes por semana, com duração de 45 ...

  3. Embodied Rhythm: Commentary on "The Contribution of Anthropometric Factors to Individual Differences in the Perception of Rhythm" by Neil P. McAngus Todd, Rosanna Cousins, and Christopher S. Lee

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    Bruno H. Repp

    2007-01-01

    Full Text Available Todd, Cousins, and Lee (2007 have presented some intriguing data suggesting that body size, as measured by standard anthropometric indices, is related to the preferred beat period in a perceptual task. Curiously, however, they did not find a significant sex difference, even though the women in their sample were clearly smaller than the men. Another recent study of preferred spontaneous tempo (McAuley et al., 2006 likewise failed to find a sex difference in a large sample of young adults. It is unclear why body size should have an effect only within each sex group.

  4. Time-Lapse Analysis of Methane Quantity in the Mary Lee Group of Coal Seams Using Filter-Based Multiple-Point Geostatistical Simulation.

    Science.gov (United States)

    Karacan, C Özgen; Olea, Ricardo A

    2013-08-01

    Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area. The systematic approach presented in this paper is the first time in literature that history matching, TIs of GIPs and filter simulations are used for degasification performance evaluation and for assessing GIP for mining safety. Results from this study showed that using production history matching of coalbed methane wells to determine time-lapsed reservoir data could be used to compute spatial GIP and representative GIP TIs generated through Voronoi decomposition

  5. Chronic depression treated successfully with novel taping therapy: a new approach to the treatment of depression

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    Han CH

    2016-06-01

    Full Text Available Chang Hyun Han,1,* Hwa Soo Hwang,2,* Young Joon Lee,3 Sang Nam Lee,4 Jane J Abanes,5 Bong Hyo Lee6 1Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon, 2Chims-Saengvit Oriental Medicine Clinic, Seoul, 3Department of Preventive Korean Medicine, 4Department of Qigong, College of Korean Medicine, Daegu Haany University, Gyeongsangbuk-do, South Korea; 5Daniel K Inouye Graduate School of Nursing, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; 6Department of Acupuncture, Moxibustion and Acupoint, College of Korean Medicine, Daegu Haany University, Daegu, South Korea *These authors contributed equally to this work Introduction: Despite improved research in the treatment, depression remains difficult to treat. Till date, successful treatment of depression using taping therapy has not been known yet. We report cases where patients with severe depressive symptoms were successfully treated by taping therapy, a new approach.Methods: In case 1, a patient was taking several psychiatric medications for 10 years and admitted often to the psychiatric hospital with a leaning head, flexible legs, and nearly closed eyes; in case 2, a patient after a hysterectomy complained with heart palpitations, depressive- and anxiety-like behaviors, insomnia, and gastrointestinal problems; and in case 3, a patient with complaints of adverse effects from antidepressant medications had suicidal thoughts frequently. The medical tapes were placed on acupoints, trigger points, and pain points found by finger pressing examination in the chest, sides, and upper back of the patients.Results: In case 1, the patient started weeping immediately after the first treatment. He discontinued psychiatric drugs and returned to baseline functioning after 2 months. In case 2, the patient felt at ease showing decreased palpitation immediately after the first treatment, and after 1 week, she quit medications. In case 3, the patient experienced a

  6. Expression of circulating leucocytes before, during and after myiasis by Dermatobia hominis in experimentally infected rats Expressão de leucócitos na circulação sangüínea antes, durante e após miíase por Dermatobia hominis em ratos experimentalmente infectados

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    Jomara M. Gonçalves

    2007-10-01

    Full Text Available Expression of circulating white blood cells was investigated in rats (Rattus norvegicus experimentally infected with larvae of Dermatobia hominis, the human bot fly. Leucocytes were counted prior to infection (control group as well as at 6, 10, 15, 20 and 28 days post-infection (dpi and at 7, 15, 30 and 60 days post-larval emergence (dple. Total leucocyte numbers did not differ markedly among the groups. Significant differences were registered when values from control and animals harboring each larval stage of D. hominis were compared; with crescent rank: L1-, L2-, control and L3-infected groups. Leucocyte numbers were significantly higher in the control, 15, 20 or 28 dpi groups than in the 6 dpi animals. Higher counts were observed in control, L2- or L3-infected rats than L1-infected animals. Neutrophils, eosinophils and both large and small lymphocytes were also counted and analyzed. Basophils and monocytes were insufficient in number to permit statistical studies. These results stimulate the continuity of the studies about the host-parasite relationship in the dermatobiosis.A expressão de leucócitos sangüínea foi investigada em ratos (Rattus norvegicus experimentalmente infectados com larvas de Dermatobia hominis. As células foram contadas antes, durante, aos 6, 10, 15, 20 e 28 dias pós-infestação (dpi, e aos 7, 15, 30 e 60 dias pós-emergência das larvas dos hospedeiros. O total de leucócitos não apresentou marcante diferença entre todos os grupos de animais. Todavia, diferenças significantes foram observadas quanto ao parasitismo pelos estádios larvares, com nível crescente: L1, L2, controle e L3. Na comparação entre grupos: o número de leucócitos foi significativo pró-controle, -15, -20 ou -28 dpi do que aos 6 dpi; e pró-controle, -L2 ou -L3 do que para L1. Neutrófilos, eosinófilos e linfócitos (pequenos e grandes foram também analisados. Em contraste, o número insuficiente de basófilos e monócitos n

  7. Desempenho e parâmetros sangüíneos de eqüinos em crescimento submetidos a dietas com diferentes níveis de farelo de canola Performance and blood parameters of growing equine fed diets with different levels of canola meal

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    Kátia de Oliveira

    2001-02-01

    Full Text Available Utilizando potros, avaliaram-se dietas em que a proteína do farelo de soja foi substituído em diferentes níveis (0; 35; 65 e 100% pela do farelo de canola. As rações foram isoprotéicas ( 17% PB e isocalóricas (4200 kcal/kg. Foram utilizados 16 eqüinos da raça Mangalarga, sendo oito machos e oito fêmeas, com média de dez meses e 218 kg PV inicial, consumindo um total de 2,5% PV, na matéria seca (MS. A dieta era composta por 40% de volumoso e 60% de concentrado. O delineamento experimental utilizado foi em blocos ao acaso, considerando quatro blocos e quatro tratamentos. Não se verificou efeito dos tratamentos sobre as variáveis de desempenho (ganho diário de peso vivo, altura na cernelha, perímetro torácico e perímetro da canela e parâmetros sangüíneos (glicose e uréia dos potros em crescimento. Nos concentrados para potros dos 9 a 11,5 meses de idade, o farelo de soja pode ser substituído pelo farelo de canola.Diets composed by four different levels (0; 53; 65 and 100% of canola meal replacing soybean meal crude protein (CP were evaluated using foals. The diets were isoproteic (17% CP and isocaloric (4200 kcal/kg. Sixteen Managalarga breed foals, eight males and eight females, averaging 10 months and 218 kg LW, fed a total intake of 2.5% LW on dry matter (DM basis were used. The diet was composed by 60:40 forage to concentrate ratio. A completely block experimental design, with four blocks and four treatments, was used. There were no effect of treatments on the performance variables (average daily gain, wither height, heart girth and cannon bone circumference and blood parameters (glucose and urea of growing foals. In the concentrate for growing foals from 9 to 11.5 months old, the soybean meal can be replaced by canola meal.

  8. Transfusão sangüínea no intra-operatório, complicações e prognóstico Transfusión sanguínea en el intraoperatorio, complicaciones y pronóstico Complications and prognosis of intraoperative blood transfusion

    Directory of Open Access Journals (Sweden)

    João Manoel Silva Junior

    2008-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Transfusões sangüíneas no intra-operatório estão associadas a aumento de complicações no pós-operatório e custos hospitalares. Portanto, este estudo avaliou as características, complicações e possíveis fatores de riscos para morte em pacientes cirúrgicos que necessitaram de transfusões sangüíneas no intra-operatório. MÉTODO: Coorte prospectiva, durante período de um ano, no centro cirúrgico de hospital terciário. Incluíram-se pacientes com idade acima de 18 anos que necessitaram de transfusões sangüíneas no intra-operatório. Testemunhas de Jeová, pacientes que receberam transfusões prévias, falência coronariana e lesão encefálica aguda foram excluídos. RESULTADOS: O estudo envolveu 80 pacientes, com idade média de 68,4 ± 14,1 anos. Os pacientes ASA II foram prevalentes com 69,6% dos casos, os escores APACHE II e POSSUM foram em média, respectivamente, 13,6 ± 4,4 e 37,5 ± 11,4. A hemoglobina média no momento da transfusão era 8,2 ± 1,8 g.dL-1 e 19% dos pacientes apresentavam hemoglobina maior que 10 g.dL-1. Os pacientes receberam em média 2,2 ± 0,9 UI de concentrados de hemácias. A mortalidade hospitalar foi 26,3%. As complicações pós-transfusões totalizaram 57,5% dos casos no pós-operatório e a mais freqüente foi infecção. Foram fatores independentes de morte na regressão logística os escores APACHE II (OR = 1,34; IC 95% 1,102 - 1,622, POSSUM (OR = 1,08; IC 95% 1,008 - 1,150 e número de unidades de concentrados de hemácias recebidas (OR = 2,22; IC 95% 1,100 - 4,463. Quanto maior o número de transfusões sangüíneas, maiores as incidências de complicações e mortalidade. CONCLUSÕES: O valor de hemoglobina e o número de unidades de concentrados de hemácias utilizados foram elevados comparados com os estudos que preconizam estratégias restritivas. Foi encontrada nesta amostra alta incidência de complicações, principalmente infecções, e elevada

  9. Parâmetros sangüíneos e urinários, no pré e pós parto, de búfalas criadas em sistema exclusivo de pastejo The blood and urinary values in the pre and pos-parturient period of buffaloes, kept on exclusive pasture feeding

    Directory of Open Access Journals (Sweden)

    Carlos Magno Chaves de Oliveira

    2003-06-01

    Full Text Available Foi avaliada a ocorrência de alterações nas concentrações de glicose sanguínea, proteína plasmática total, hematócrito e presença de corpos cetônicos na urina de oito búfalas leiteiras da raça Murrah, com idade variando entre 5 e 10 anos, com no mínimo duas lactações, clinicamente sadias, desde 60 dias antes até 60 dias pós-parto. As concentrações médias de glicose sangüínea e o valor médio do hematócrito diminuíram significativamente no pós-parto (pEight lactating buffaloes of the Murrah breed were used from 60 days before up to 60 days after calving, in order to evaluate alterations in the concentration of blood glucose, total plasmatic protein, haematocrit and the presence of ketonic bodies in the urine. The 5 to 10- year old buffaloes were clinically healthy and had had at least two lactations. During the experimental period the animals were maintained on Brachiaria brizantha pasture and supplemented with a mineral mixture and water.The media concentrations of blood glucose and the media values of the haematocrit diminished significantly after calving (p<0,05. The concentrations of total plasmatic protein did not show significant variation during the pre and post-calving period. The ketonic bodies in the pre-calving period were only detected in the urine of one buffaloe, but after the 32nd day of lactation ketonic bodies were detected in all animals. There was a direct relationship between the color of the urine positive by the Rothera test and blood glucose concentrations. It can be concluded that at the beginning of lactation the buffaloes had an energetic deficit, characterized by a decline of blood glucose concentrations and the presence of ketonic bodies in the urine, and that lactation caused a progressive decline of the hematocrit, but that the concentration of total plasmatic protein did not vary during the pre and post-calving period.

  10. Mait-Väinu Sooäär : soigumist ma pole ära õppinud / Mait-Väinu Sooäär ; interv. Heli Salong

    Index Scriptorium Estoniae

    Sooäär, Mait-Väinu

    2006-01-01

    Endine KEK-i tippjuht, Kingissepa Rajooni Täitevkomitee esimehe ja Saare maavanema asetäitja, ärimees, kes praegu projekteerib reoveepuhasteid ja annab konsultatsioone vastab küsimustele oma karjäärist, õpingutest ja eraelust

  11. Optimization and physicochemical characterization of a cationic lipid-phosphatidylcholine mixed emulsion formulated as a highly efficient vehicle that facilitates adenoviral gene transfer

    Directory of Open Access Journals (Sweden)

    Kim SY

    2017-10-01

    Full Text Available Soo-Yeon Kim,1,2 Sang-Jin Lee,2 Jin-Ki Kim,3 Han-Gon Choi,3 Soo-Jeong Lim1 1Department of Bioscience and Bioengineering, Sejong University, Seoul, Kwangjin-gu, Seoul, 2Immunotherapeutics Branch, Research Institute, National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do, 3College of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, Sangnok-gu, Ansan, Republic of Korea Abstract: Cationic lipid-based nanoparticles enhance viral gene transfer by forming electrostatic complexes with adenoviral vectors. We recently demonstrated the superior complexation capabilities of 1,2-dioleoyl-3-trimethylammonium propane (DOTAP emulsion compared with a liposomal counterpart but the cytotoxicity of DOTAP emulsions remained a challenge. The present study is aimed at formulating an emulsion capable of acting as a highly effective viral gene transfer vehicle with reduced cytotoxicity and to physicochemically characterize the structures of virus-emulsion complexes in comparison with virus–liposome complexes when the only difference between emulsions and liposomes was the presence or absence of inner oil core. The emulsion formulation was performed by 1 reducing the content of DOTAP while increasing the content of zwitterionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC, and 2 optimizing the oil content. The complexation capability of formulated DOTAP:DMPC mixed emulsions was similar to those of emulsions containing DOTAP alone while displaying significantly lower cytotoxicity. The complexation capabilities of the DOTAP:DMPC mixed emulsion were serum-compatible and were monitored in a variety of cell types, whereas its liposomal counterpart was totally ineffective. Characterization by scanning electron microscopy, transmission electron microscopy, atomic force microscopy, and dynamic light scattering studies indicated that the optimized emulsions spontaneously surrounded the virus particles to generate emulsions that

  12. Liver-targeted cyclosporine A-encapsulated poly (lactic-co-glycolic acid nanoparticles inhibit hepatitis C virus replication

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    Jyothi KR

    2015-01-01

    Full Text Available KR Jyothi,1 Jagadish Beloor,2 Ara Jo,1 Minh Nam Nguyen,1 Tae Gyu Choi,1 Jin-Hwan Kim,1 Salima Akter,1 Sang-Kyung Lee,2 Chi Hoon Maeng,3 Hyung Hwan Baik,1 Insug Kang,1 Joohun Ha,1 Sung Soo Kim1 1Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; 2Department of Bioengineering and Institute for Bioengineering and Biopharmaceutical Research, Hanyang University, Seoul, Republic of Korea; 3Department of Medical Oncology and Hematology, Kyung Hee University Hospital, Seoul, Republic of Korea Abstract: Therapeutic options for hepatitis C virus (HCV infection have been limited by drug resistance and adverse side effects. Targeting the host factor cyclophilin A (CypA, which is essential for HCV replication, offers a promising strategy for antiviral therapy. However, due to its immunosuppressive activity and severe side effects, clinical application of cyclosporine A (CsA has been limited as an antiviral agent. To overcome these drawbacks, we have successfully developed a liver-specific, sustained drug delivery system by conjugating the liver-targeting peptide (LTP to PEGylated CsA-encapsulated poly (lactic-co-glycolic acid (PLGA nanoparticles. Furthermore, our delivery system exhibited high specificity to liver, thus contributing to the reduced immunosuppressive effect and toxicity profile of CsA. Finally, targeted nanoparticles were able to effectively inhibit viral replication in vitro and in an HCV mouse model. As a proof of principle, we herein show that our delivery system is able to negate the adverse effects of CsA and produce therapeutic effects in an HCV mouse model.Keywords: HCV, liver-targeting peptide, targeted drug delivery

  13. Mata Ketiga: Se Laen, Sang Pembebas Sistem Pendidikan Tinggi Akuntansi

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    Iwan Triyuwono

    2010-04-01

    Full Text Available The objectives of the study are to criticize the existing accounting education especially in Indonesian universities and to give an alternative idea for a better one. It is done as there is a strong indication that accounting education is driven by intellectual intelligence, market, and other artificial interests. Through a deconstruction approach and critical analysis, the study suggests the internalization of “Mata Ketiga” (the Third Eye in accounting curriculum. Mata Ketiga, that refers to spiritual intelligence, is “the Other” that is consciously entered to the singularity of intellectual intelligence of modern curriculum. Under the internalization of Mata Ketiga, accounting education can be emancipated from the domination of intellectual intelligence, market, and other artificial interests. By doing so, the education may guide an accounting student to find his/her “real self” without neglecting contemporary accounting competence.

  14. "Jõulujazzi" kõige "jazzim" kontsert / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2011-01-01

    29. novembrist kuni 17. detsembrini toimunud festivali kontsertidest, pikemalt 11. detsembril Vene Kultuurikeskuses kontserdist, kus esinesid trummar Francis Lassus, saksofonist Philippe Sellam ja bassist Linley Marthe

  15. Temporomandibular joint dislocation in Nairobi | Sang | East African ...

    African Journals Online (AJOL)

    Design: Descriptive cross-sectional study. Setting: University of Nairobi Dental Hospital (UNDH) from January 1995 to July 2005. ... Trauma was implicated as an aetiology in only five (17%) of the cases while the remaining majority of twenty four (83%) cases were spontaneous. Amongst the causes of spontaneous TMJ ...

  16. SERINGUE LOUIS JUBÉ POUR LA TRANSFUSION DU SANG PUR

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    Academia Nacional de Medicina

    2011-01-01

    Full Text Available

    DENOMINACIÓN:  

    Fabricante: Duffaud & Cie

    Año: 1924

    Medidas: 19,5 x 6 cm

    Volumen: 5 cc

    Materiales: Acero, vidrio y caucho 

    Esta jeringa para transfusión de sangre fue diseñada en Paris por el médico francés, Louis Jubé. Fue desarrollada en 1923, aunque la publicación de la patente sólo se registra hasta el 1 de julio de 1924. 

    Este sistema de transfusión de sangre fue el más utilizado en Europa durante la década de los años veinte. La jeringa está compuesta por un cilindro de vidrio y dispone de dos conexiones laterales que, por medio de agujas de diverso calibre, permitían la punción del donante y el receptor. La jeringa más utilizada fue de 5 cc. Para su uso, se debía punzar primero al receptor y una vez canalizada la vena se conectaba al donante. La sangre llenaba el émbolo y luego de varias aspiraciones se trasmitía la sangre al receptor a un ritmo de 5cc cada 3-4 segundos. Este tipo de jeringa podía llegar a permitir transfusiones de 200cc hasta 500cc en algunos casos. Sin embargo, a medida que pasaba el tiempo, la transfusión se dificultaba debido a la coagulación de la sangre y era necesario iniciar el proceso nuevamente. 

  17. DIE PLEK VAN SANG EN MUSIEK IN DIE PROTESTANTSE ...

    African Journals Online (AJOL)

    Test

    4 vers 21 „die vader van almal wat op die siters en fluite speel” genoem. Eintlik is al hierdie oeroue gedeeltes ... en trou; en die liedere skik hulle na hierdie vorme en hierdie inhoud. Dit is veral by hierdie liedere dat ons ..... Van der Leeuw slegs 'n bladsy ver der; „Terstond na zijn binnenkomst spreekt de Dienaar het Votum .

  18. Prevalence des hemolysines chez les donneurs de sang de groupe ...

    African Journals Online (AJOL)

    Objectifs : Déterminer la fréquence et le titre des hémolysines anti-A et anti-B dans la population des donneurs O et de prédire de l'intérêt de la systématisation de leur recherche chez tous les donneurs O par l'évaluation du risque d'accident transfusionnels liés aux hémolysines. Méthodologie : Etude prospective au ...

  19. Avaliação do efeito de sopas desidratadas ricas em fibras na redução do colesteroal sangüíneo em ratos Evaluation of the cholesterol-lowering efect of high-fiber dehydrated soup in rats

    Directory of Open Access Journals (Sweden)

    Hercia Stampini Duarte

    1998-12-01

    Full Text Available Neste estudo foi avaliado o efeito de quatro formulações dietéticas ricas em fibra solúvel na redução de colesterol sangüíneo em ratos. As formulações foram preparadas com farinha de soja desengordurada, farelo de aveia, cebola desidratada, fibra de soja, condimentos e aromas. Duas das formulações continham feijão preto FP(+ e FP(-, nos níveis de 40 e 30%, respectivamente. As outras duas continham feijão vermelho FV(+ e FV(-, nesses mesmos teores. Foram utilizados seis grupos de oito ratos machos, com peso médio inicial de 200g. O grupo Padrão recebeu dieta basal. O grupo Controle recebeu dieta de composição semelhante à Padrão, porém, acrescida de 1% de colesterol cristalino e 0,1% de ácido cólico. As demais dietas foram semelhantes ao grupo Controle, substituídas pelas formulações FV(+, FP(+, FV(- e FP(-, de modo a fornecerem 7,4% de fibra total da dieta. Ratos alimentados com dieta do grupo Controle apresentaram aumento significativo dos níveis de colesterol sérico, peso dos fígados, colesterol e lipídio total das fezes e dos fígados, em relação ao grupo recebendo dieta Padrão. As dietas FV(+, FP(+, FV(- e FP(-, não diferiram entre si quanto ao efeito nos níveis de lipídios séricos e glicose, no peso e lipídio total dos fígados e no peso, umidade e nitrogênio das fezes. No entanto, reduziram significativamente os níveis sangüíneos de colesterol total em 29,0%, os níveis de HDL - colesterol em 34,0%, o peso dos fígados em 11,7% e o colesterol do fígado em 9,0% em relação à dieta Controle. As dietas de feijão vermelho proporcionaram maior redução de colesterol no fígado e maior excreção de lipídio e colesterol nas fezes comparadas com as de feijão preto.The effect of 4 high fiber dietary formulas on reducing blood cholesterol levels in rats was evaluated in the present study. The products were formulated with defatted soy flour, oat bran, dehydrated onion, soy fiber and spices. Two of

  20. Metabolismo miocárdico após cardioplegia sangüínea hipotérmica retrógrada contínua com indução anterógrada normotérmica Myocardial metabolism after hypothermic retrograde continuous blood cardioplegia with anterograde warm cardioplegic induction

    Directory of Open Access Journals (Sweden)

    Claudio G. Sobrosa

    2005-12-01

    Full Text Available OBJETIVO: Determinar as alterações sofridas pelo miocárdio durante a cardioplegia sangüínea hipotérmica retrógrada contínua com a adição da indução cardioplégica anterógrada normotérmica. MÉTODO: Análise metabólica da cardioplegia sangüínea hipotérmica retrógrada contínua com indução anterógrada normotérmica em estudo prospectivo de 15 pacientes consecutivos. Amostras de sangue arterial e do seio coronário foram simultaneamente colhidas para análise do conteúdo de oxigênio e da concentração de lactato. Quatro biópsias miocárdicas foram obtidas para análise dos níveis de ATP, ADP, AMP e lactato no miocárdio. A isoenzima CK-MB foi analisada no sangue venoso. RESULTADOS: Não houve mortalidade no grupo. Nenhum paciente necessitou de suporte inotrópico na saída de CEC e não foi detectado IAM per ou pós-operatório. Ocorreu diminuição da extração artério-venosa do lactato e do oxigênio pelo coração durante a reperfusão, havendo uma recuperação parcial ao final de 60 minutos de reperfusão. Os níveis miocárdicos de ATP e de seus nucleotídeos foram mantidos durante o pinçamento aórtico, porém houve redução destes nos primeiros 30 minutos de reperfusão. O lactato acumulou-se no músculo cardíaco durante o pinçamento aórtico, havendo redução durante a reperfusão. CONCLUSÕES: Concluímos por uma análise metabólica que o método não conseguiu evitar o metabolismo anaeróbico durante o período de pinçamento aórtico e que somente com 60 minutos de reperfusão foi observado um grau de recuperação metabólica satisfatória. Provavelmente essas alterações são devido à injúria isquêmica celular ocorrida durante o pinçamento aórtico e parecem ter efeito transitório. Observamos melhora da proteção miocárdica com o acréscimo da indução cardioplégica anterógrada normotérmica.OBJECTIVE: To determinate the alterations suffering by myocardium in the hypothermic retrograde

  1. Parâmetros ruminal, sangüíneo e urinário e digestibilidade de nutrientes em novilhas leiteiras recebendo diferentes níveis de monensina Effects of different dietary levels of monensin on nutrient digestibility and on ruminal, blood and urinary metabolites in dairy heifers

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius Morais de Oliveira

    2005-12-01

    Full Text Available Objetivou-se verificar a influência da inclusão de diferentes níveis do ionóforo monensina sódica na dieta sobre os parâmetros ruminal, sangüíneo e urinário e a digestibilidade aparente em novilhas leiteiras. Foram coletadas amostras de líquido ruminal (imediatamente antes e duas horas após a alimentação, sangue, urina e fezes de 28 novilhas da raça Holandesa mantidas em regime de confinamento por 84 dias. As dietas possuíam 32,84% de concentrado (grão de milho, farelo de soja, uréia e mistura mineral, 33,58% de silagem de milho e 33,58% de cana-de-açúcar na matéria seca. Os níveis de ionóforo avaliados foram 0, 14, 28 e 42 mg de monensina/kg de matéria seca da dieta. O experimento foi instalado conforme delineamento inteiramente casualizado, com quatro tratamentos e sete repetições, realizando-se estudos de regressão e contrastes ortogonais. Antes da alimentação, a monensina não influenciou o pH ruminal e a concentração de amônia e dos ácidos acético, propiônico e butírico, mas promoveu redução da relação acetato:propionato. Duas horas após a alimentação, verificou-se redução do pH e da relação acetato:propionato; e aumento da concentração de ácido propiônico. O estudo de contrastes revelou que ocorreu diminuição da concentração de amônia antes da alimentação. Não foram verificadas mudanças significativas nas concentrações de glicose e uréia sangüínea. A monensina também não influenciou os consumos de matéria seca (MS, matéria orgânica, proteína bruta, extrato etéreo (EE, carboidratos totais (CHOT e fibra em detergente neutro. As digestibilidades da MS, EE e CHOT e a perda de nitrogênio urinário apresentaram respostas quadráticas.The objective of this trial was to study the effects of different dietary levels of the ionophore monensin on apparent digestibility of nutrients and on ruminal, blood, and urinary metabolites in dairy heifers. Samples of ruminal fluid (pre

  2. Interferência dos ácidos graxos ômega-3 nos lipídeos sangüíneos de ratos submetidos ao exercício de natação Omega-3 fatty acids interference on the blood lipids of rats subjected to swimming exercise

    Directory of Open Access Journals (Sweden)

    Bettina Moritz

    2008-12-01

    Full Text Available OBJETIVO: Investigar os efeitos da suplementação com ácidos graxos ômega-3, nas doses de 0,5 e 1,0g/kg/dia, nos lipídeos sangüíneos de ratos submetidos ou não ao protocolo do nado. MÉTODOS: Ratos Wistar foram divididos em grupos: controle, controle+nado, ácidos graxos ômega-3 e ácidos graxos ômega-3+nado. Os ácidos graxos ômega-3 e ácidos graxos ômega-3+nado receberam suplementação; os demais receberam água por gavagem. Os controle+nado e ácidos graxos ômega-3+nado foram submetidos ao exercício. Foram avaliadas as concentrações plasmáticas de colesterol total, triglicérides e lipoproteína de alta densidade, antes e após os procedimentos experimentais. RESULTADOS: No protocolo de 0,5g/kg/dia, em relação às concentrações de colesterol total, foi observada redução significativa proporcionalmente maior no grupo ácidos graxos ômega-3+nado, apesar de o grupo controle+nado e o ácidos graxos ômega-3 também terem apresentado diminuição. No ensaio de 1,0g/kg/dia todos os grupos apresentaram uma diminuição que foi maior, respectivamente, no ácidos graxos ômega-3+nado e, a seguir, no ácidos graxos ômega-3. Quanto aos triglicérides, foram encontradas reduções em todos os grupos experimentais, que foi maior no grupo ácidos graxos ômega-3+nado, do protocolo de 0,5g/kg/dia, enquanto que no de 1,0g/kg/dia a diminuição foi significativa apenas nos grupos ácidos graxos ômega-3 e ácidos graxos ômega-3+nado. Quanto ao HDL, no protocolo de 0,5g/kg/dia foi encontrado aumento nos animais que não foram suplementados, enquanto que em todos os grupos de 1,0g/kg/dia houve uma diminuição do HDL. CONCLUSÃO: A suplementação com ácidos graxos ômega-3 nas doses 0,5 ou 1,0g/kg/dia, associada ao nado, reduzem as concentrações plasmáticas de colesterol total e triglcérides, mas estudos adicionais, também com outras doses, são necessários para a compreensão da relação entre a ingestão de óleo de peixe e

  3. Distribuição fenotípica e a freqüência genotípica do sistema sangüíneo Duffy em pacientes com a doença de Jorge Lobo Phenotypic distribution and genotypic frequency of the Duffy blood group system in Jorge Lobo's disease patients

    Directory of Open Access Journals (Sweden)

    Eliane A. Silva

    2006-12-01

    Full Text Available A doença de Jorge Lobo é uma micose cutânea e subcutânea de evolução crônica, causada pelo Lacazia loboi. Os mecanismos envolvidos na suscetibilidade/resistência do hospedeiro frente ao agente não estão ainda elucidados, dentre eles encontra-se a constituição genética. Portanto, o objetivo deste trabalho é avaliar a distribuição fenotípica do grupo sangüíneo Duffy em pacientes com doença de Jorge Lobo e calcular suas freqüências gênicas. Foram analisados 21 pacientes, 13 caucasóides e oito mestiços (tipo moreno claro, provenientes do estado do Acre, e 44 indivíduos, não acometidos por esta doença, habitantes da cidade de Rio Branco (AC, como grupo controle. O fenótipo Duffy foi definido pela presença dos antígenos nas hemácias pela reação de aglutinação dos eritrócitos com anti-soros anti-Fya e anti-Fyb incubando-se a 37ºC e aplicando-se o teste da antiglobulina humana. Os resultados mostram que a distribuição fenotípica do sistema Duffy nos pacientes difere significativamente daquela observada nos controles, pela alta freqüência de indivíduos com fenótipo Fy(a-b-. Observa-se claramente que os pacientes apresentam maior freqüência do alelo FY e menor do alelo FYA do que os controles. O alelo FYB (não inclui os alelos que não são expressos tem praticamente a mesma freqüência nos dois grupos. Com relação à comparação entre distribuição do grupo sangüíneo Duffy com as formas clínicas, sugere maior número de pacientes com forma localizada da doença de Jorge Lobo apresentando um predomínio do fenótipo Fy(a-b+ seguido do fenótipo Fy(a-b- e inexistência do fenótipo Fy(a+b-. Por outro lado, temos a forma disseminada com maior incidência de fenótipo Fy(a+b-. A forma multifocal foi menos expressiva. Desse modo, podemos inferir uma provável prevalência de fenótipo Duffy negativo na região por nós estudada e os poucos dados disponíveis até o momento tornam clara a necessidade de

  4. Femmes aux petits soins : la fêlure d’un idéal dans deux nouvelles de F.S. Fitzgerald The Lees of Happiness et An Alcoholic Case

    OpenAIRE

    DELESALLE-NANCEY, Catherine

    2017-01-01

    Écrites à 17 ans d’intervalle, ces deux nouvelles de Fitzgerald mettent en scène des artistes dont la maladie pour l’un (« The Lees of Happiness ») et l’alcoolisme pour l’autre (« An Alcoholic Case ») ont eu raison des facultés créatrices. Pourtant, l’attention se porte moins sur les malades que sur celles qui les soignent, et embrassent ainsi un rôle traditionnellement dévolu aux femmes : l’épouse aimante sacrifiant tout pour son mari grabataire et l’infirmière dévouée investie d’une mission...

  5. Protective efficacy in mice of monovalent and trivalent live attenuated influenza vaccines in the background of cold-adapted A/X-31 and B/Lee/40 donor strains.

    Science.gov (United States)

    Jang, Yo Han; Lee, Eun-Young; Byun, Young Ho; Jung, Eun-Ju; Lee, Yoon Jae; Lee, Yun Ha; Lee, Kwang-Hee; Lee, Jinhee; Seong, Baik Lin

    2014-01-23

    Influenza virus continues to take a heavy toll on human health and vaccination remains the mainstay of efforts to reduce the clinical impact imposed by viral infections. Proven successful for establishing live attenuated vaccine donor strains, cold-adapted live attenuated influenza vaccines (CAIVs) have become an attractive modality for controlling the virus infection. Previously, we developed the cold-adapted strains A/X-31 and B/Lee/40 as novel donor strains of CAIVs against influenza A and B viruses. In this study, we investigated the protective immune responses of both mono- and trivalent vaccine formulations in the mouse model. Two type A vaccines and one type B vaccine against A/New Caledonia/20/99 (H1N1), A/Panama/2007/99 (H3N2), and B/Shangdong/7/97 in the background of the A/X-31 ca or B/Lee/40 ca were generated by a reassortment procedure and evaluated for their immunogenicity and protective efficacy. Each monovalent vaccine elicited high levels of serum antibodies and conferred complete protection against homologous wild type virus infection. As compared to the monovalent vaccines, trivalent formulation induced higher levels of type A-specific serum antibodies and slightly lower levels of type B-specific antibodies, suggesting an immunological synergism within type A viruses and an interference in the replication of type B virus. Relatively lower type B-specific immunogenicity in trivalent vaccine formulation could be effectively implemented by increasing the vaccine dose of influenza B virus. These results of immunogenicity, protection efficacy, and immunological synergism between type A vaccines provide an experimental basis for optimal composition of trivalent vaccines for subsequent developments of multivalent CAIVs against seasonal and pandemic influenza viruses. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Flux of nitrogen, phosphorus, and suspended sediment from the Susquehanna River Basin to the Chesapeake Bay during Tropical Storm Lee, September 2011, as an indicator of the effects of reservoir sedimentation on water quality

    Science.gov (United States)

    Hirsch, Robert M.

    2012-01-01

    Concentrations of nitrogen, phosphorus, and suspended sediment are measured at the U.S. Geological Survey streamgage at Conowingo Dam at the downstream end of the Susquehanna River Basin in Maryland, where the river flows into the Chesapeake Bay. During the period September 7-15, 2011, in the aftermath of Tropical Storm Lee, concentrations of these three constituents were among the highest ever measured at this site. These measurements indicate that sediment-storage processes behind the three dams on the lower Susquehanna River are evolving. In particular, they indicate that scouring of sediment (and the nitrogen and phosphorus attached to that sediment) may be increasing with time. Trends in flow-normalized fluxes at the Susquehanna River at Conowingo, Maryland, streamgage during 1996-2011 indicate a 3.2-percent decrease in total nitrogen, but a 55-percent increase in total phosphorus and a 97-percent increase in suspended sediment. These large increases in the flux of phosphorus and sediment from the Susquehanna River to the Chesapeake Bay have occurred despite reductions in the fluxes of these constituents from the Susquehanna River watershed upstream from the reservoirs. Although the Tropical Storm Lee flood event contributed about 1.8 percent of the total streamflow from the Susquehanna River to the Chesapeake Bay over the past decade (water years 2002-11), it contributed about 5 percent of the nitrogen, 22 percent of the phosphorus, and 39 percent of the suspended sediment during the same period. These results highlight the importance of brief high-flow events in releasing nitrogen, phosphorus, and sediment derived from the Susquehanna River watershed and stored in the Conowingo Reservoir to the Chesapeake Bay.

  7. Erratum Pleurotus sajor-caju HSP100 complements a ...

    Indian Academy of Sciences (India)

    Madhu

    defect in hsp104 mutant Saccharomyces cerevisiae. Jin-Ohk Lee, Mi-Jeong Jeong, Tack-Ryun Kwon, Seung-Kon Lee, Myung-Ok Byun, Ill-Min Chung and. Soo-Chul Park 2006, J. Biosci., 31, 223–233. The following corrections require to be made in the printed version of the above article. These correc- tions will appear in ...

  8. Molecular cloning and expression of the C-terminus of spider ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 32; Issue 4. Molecular cloning and expression of the C-terminus of spider flagelliform silk protein from Araneus ventricosus. Kwang Sik Lee Bo Yeon Kim Yeon Ho Je Soo Dong Woo Hung Dae Sohn Byung Rae Jin. Articles Volume 32 Issue 4 June 2007 pp 705-712 ...

  9. Hout in sy brood! lets oor Calvyn se Bybelgebruik

    African Journals Online (AJOL)

    Die Targumitks wat in die Biblia Rabbinica (die Bom- berg-uitgawe van 1525) opgeneem is, laat die betrokke sinsnede waarom dit hier gaan, weg. Die Targum Jonathan (Sperber 3:164) bied egter die variant van die werkwoord wat ook in die Septuagint voorkom. Die betrokke sinsnede lees in hier die teks soos volg: Laat ...

  10. Materials Research Society (MRS) 2014 Fall Meeting, Boston, MA on November 30 December 5, 2014

    Science.gov (United States)

    2015-12-18

    strong chirality, and optical nonlinearity management . Consequently, optical metamaterials promise novel applications in optics and photonics, which...and Eric A. Armour and Balakrishnan Krishnan and Soo Min Lee and George D. Papasouliotis MRS Online Proceedings Library, Volume 1736, 2015, mrsf14-1736

  11. 22nd September 2010 - Korean Minister of Education, Science and Technology J.-H. Lee signing the guest book and exchanging gifts with CERN Director-General R. Heuer and Head of International Relations F. Pauss; visiting ALICE exhibition with Collaboration Spokesperson J. Schukraft; accompanied throughout by Adviser R. Voss.

    CERN Multimedia

    Teams : M. Brice ; JC Gadmer

    2010-01-01

    22nd September 2010 - Korean Minister of Education, Science and Technology J.-H. Lee signing the guest book and exchanging gifts with CERN Director-General R. Heuer and Head of International Relations F. Pauss; visiting ALICE exhibition with Collaboration Spokesperson J. Schukraft; accompanied throughout by Adviser R. Voss.

  12. Balanço eletrolítico e níveis de proteína bruta sobre parâmetros sangüíneos e ósseos de frangos de corte aos 21 dias de idade Electrolyte balance and crude protein levels on blood and bone parameters of 21 days broiler chicks

    Directory of Open Access Journals (Sweden)

    Flávio Medeiros Vieites

    2004-12-01

    Full Text Available Foi realizado um experimento com o objetivo de determinar os melhores valores de balanço eletrolítico (BE para frangos de corte de 1 a 21 dias. Utilizaram-se 2.112 pintinhos da marca comercial Ross, machos, criados em boxes de galpão de alvenaria, cobertos com maravalha e alimentados com duas rações basais, uma com 20 e outra com 23% de proteína bruta (PB à base de milho e de farelo de soja, combinadas com níveis de BE de 00; 50; 100; 150; 200; 250; 300 e 350 mq/kg. Foi utilizado delineamento experimental inteiramente casualizado, em esquema fatorial 8x2 (oito níveis de BE e dois níveis de PB, seis repetições e 22 aves por unidade experimental. Avaliaram-se os níveis sangüíneos de cálcio, fósforo e proteínas totais aos 21 dias de idade. As cinzas, o cálcio, o fósforo, o potássio, o sódio e o magnésio dos ossos também foram quantificados. Aos 21 dias de idade, os melhores valores estimados de BE foram 168 (20% PB e 245 (23% PB mEq/kg para o cálcio no sangue. O valor de BE obtido para o menor nível de proteínas totais foi de 189 (23% PB mEq/kg. Os melhores valores de BE no sangue foram os pontos de mínimo na curva de regressão. O melhor valor de BE para o cálcio no tibiotarso foi de 132 mEq/kg (23% PB. O BE da dieta deve situar-se entre 150 e 200 mEq/kg para frangos de corte de 1 a 21 dias de idade.An experiment was conducted to determine the best electrolyte balance (EB for broiler chicks from one to 21 days of age, based on blood and bone parameters. One day old chicks, male, Ross were reared on floor covered with shaving woods and fed with two corn-soybean meal based diet with 20 and 23% of crude protein (CP combined with 0; 50; 100; 150; 200; 250; 300 and 350 mEq/kg of EB. The experiment was analised as a completely randomized design in a factorial arrangement of treatments (two CP levels and eight EB with six replicates of 22 chicks each. It were evaluated blood levels of calcium, phosphorus and total proteins

  13. Variedades de feijão e seus efeitos na qualidade protéica, na glicemia e nos lipídios sangüíneos em ratos Varieties of beans and their effects on protein quality, glicemy, and blood lipids in rats

    Directory of Open Access Journals (Sweden)

    Dagnith Liz Bejarano Luján

    2008-12-01

    Full Text Available O feijão representa importante fonte de proteína e pode auxiliar na modulação dos níveis de glicose e lipídios sangüíneos. Objetivou-se avaliar o valor protéico e funcional de variedades de feijão. Para a qualidade protéica foram usados 7 grupos (n = 6 de ratos recém desmamados: um recebeu dieta aprotéica por 14 dias e os demais, dietas contendo 9-10% de proteína como caseína ou como um dos feijões (Ouro Branco, Pérola, BRS Radiante, Diamante Negro e Talismã. No segundo experimento, 4 grupos (n = 10 de ratos adultos receberam dietas de caseína, Ouro Branco, Diamante Negro e Talismã por 28 dias. Ouro Branco apresentou maior Coeficiente de Eficiência Protéica (PERr = 61,18% do que os demais e o BRS Radiante o menor (PERr = 44,60%. Quanto à Razão Protéica Líquida (NPR e à digestibilidade, não houve diferença (p > 0,05 entre os grupos, variando de 67,05 a 78,19% e de 78,70 a 84,88%, respectivamente. As dietas de Diamante Negro e Talismã promoveram redução da glicemia de 30 e 26%, respectivamente, em relação à caseína, não sendo, porém, significativa; não houve diferença (p > 0,05 entre os grupos quanto aos níveis séricos de colesterol e triacilgliceróis. Assim, de acordo com as necessidades apresentadas pelas populações, suas demandas nutricionais e funcionais podem ser supridas por diferentes feijões.Beans are important source of protein in the Brazilian staple food and may modulate the blood glucose and lipid levels. The objective of this study was to evaluate the protein quality and functional properties of varieties of beans. Seven groups (n = 6 of weaning rats were used for the bean protein quality analysis. The first group was fed protein-free diet for 14 days, and the remaining were fed diets with 9 to 10% protein provided by either casein or one of the 5 varieties of beans (Ouro Branco, Pérola, BRS Radiante, Diamante Negro, and Talismã. In a further study, 4 groups (n = 10 of adult rats were

  14. Urologic symptoms and burden of frailty and geriatric conditions in older men: the Aging Study of PyeongChang Rural Area

    Directory of Open Access Journals (Sweden)

    Jang IY

    2018-02-01

    Full Text Available Il-Young Jang,1,2 Chang Ki Lee,3 Hee-Won Jung,4,5 Sang Soo Yu,2 Young Soo Lee,1 Eunju Lee,1 Dae Hyun Kim6,7 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 2PyeongChang Health Center & County Hospital, PyeongChang, Gangwon-Do, Republic of Korea; 3Goldman Urology Clinic, Seoul, Republic of Korea; 4Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST, Daejeon, Republic of Korea; 5Geriatric Center, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-Do, Republic of Korea; 6Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; 7Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA Purpose: Frailty is an important consideration in the management of lower urinary tract symptoms and erectile dysfunction in older men; frailty increases vulnerability to treatment-related adverse outcomes, but its burden is not known. The authors aimed to examine the burden of frailty and associated geriatric conditions in community-dwelling older men.Patients and methods: A cross-sectional study was conducted with 492 community-dwelling older men (mean age, 74.2 years; standard deviation, 5.6 years. All the participants were administered the International Prostate Symptom Score (IPSS (range: 0–35 and a five-item version of the International Index of Erectile Function (IIEF-5 (range: 5–25. Frailty phenotype was assessed based on exhaustion, inactivity, slowness, weakness, and weight loss. Prevalence of frailty phenotype and geriatric conditions were assessed by the IPSS severity category (mild, 0–7; moderate, 8–19; severe, 20–35 points and the first IIEF-5 question, which assesses the confidence in erectile function (low, 1–2; moderate, 3; high, 4–5 points.Results: Older men with severe urologic

  15. Manuscripts on establishment of Korea nuclear power

    International Nuclear Information System (INIS)

    Park, Ik Su

    1999-12-01

    This book mentions establishment of Korea nuclear power with twelve manuscripts. It is comprised of twelve documents with conversation and recollection the contents of this book are summary, conversation with Yoon, Se Won, conversation with Choe, Paeng Seop, conversation with Lee, Dong Jip, conversation with Lee, Sang Su, conversation with Kim, Jong Ju, conversation with Lee, Jong Hun, conversation with Youn, Young Ryeok, conversation with Han, Pil Sun, recollection on my nuclear energy by Kim, Dong Hun, recollection on my nuclear power by Lee, Chang Gun, I and nuclear power by Park, Ik Su. It reports the establishment on history and process of Korea nuclear power plant through dialogue with twelve people.

  16. 77 FR 66912 - Soo Line Railroad Company-Abandonment Exemption-in Cook County, IL

    Science.gov (United States)

    2012-11-07

    ... governmental agencies) have been met. As a condition to this exemption, any employee adversely affected by the... condition adequately protects affected employees, a petition for partial revocation under 49 U.S.C. 10502(d..., if any, of the abandonment on the environment and historic resources. OEA will issue an environmental...

  17. “Op die aarde net soos in die hemel”: Matteus se eskatologie as die ...

    African Journals Online (AJOL)

    both these experiences are presented in Matthew as though Jesus' crucifixion and resurrection are incidents of the past. Matthew's eschatology centres on the view that the final consummation of time has already begun. The article explores the ethical appeal which is communicated through such an eschatological reading ...

  18. Soos 'n hamer wat 'n rots vermorsel”: die afrikaanse bybel van 1933 ...

    African Journals Online (AJOL)

    The 1933 translation is analysed and explained in terms of the formation of particular cultural, political and religious identities. Some of the fixed perceptions of the 1933 translation are revisited by dealing with issues like the context of the translation, its source text, the translation team, the translation process and the ...

  19. Soos 'n hamer wat 'n rots vermorsel”: die afrikaanse bybel van 1933 ...

    African Journals Online (AJOL)

    “like a hamer crushing a rock”: the afrikaans bible of 1933 as a work of translation The first complete Bible translation in Afrikaans was published in 1933. This article describes and analyses this translation. Given the new developments in translation studies, one should not evaluate a translation normatively, but rather ...

  20. Pidamata jäänud kõne / Imre Sooäär

    Index Scriptorium Estoniae

    Sooäär, Imre, 1969-

    2007-01-01

    Ilmunud ka: Lääne Elu, 10. apr. 2007, lk. 2; Hiiu Leht, 10. apr. 2007, lk. 2; Põhjarannik, 10. apr. 2007, lk. 2; Severnoje Poberezhje, 10. apr. 2007, lk. 2; Harjumaa, 10. apr. 2007, lk. 2; Virumaa Teataja, 12. apr. 2007, lk. 11; Nädaline, 12. apr. 2007, lk. 2; Sakala, 13. apr. 2007, lk. 2; Harju Ekspress, 13. apr. 2007, lk. 6; Vali Uudised, 13. apr. 2007, lk. 2; Järva Teataja, 14. apr. 2007, lk. 2; Vooremaa, 14. apr. 2007, lk. 2. Parlamendiliige leiab, et Ene Ergma oli parim Riigikogu XI koosseisu kandidaat spiikri kohale

  1. 30 CFR 250.175 - When may the Regional Supervisor grant an SOO?

    Science.gov (United States)

    2010-07-01

    ... salt sheet; (ii) That all or a portion of a potential hydrocarbon-bearing formation may lie beneath or adjacent to the salt sheet; and (iii) The salt sheet interferes with identification of the potential hydrocarbon-bearing formation. (3) The interpreted geophysical information required under paragraph (b)(2) of...

  2. Eesti õpetajate roll laste internetikasutuse sotsiaalses vahendamises / Kadri Soo, Veronika Kalmus, Mare Ainsaar

    Index Scriptorium Estoniae

    Soo, Kadri

    2015-01-01

    Artiklis käsitletakse õpetajate rolli laste ettevalmistamisel internetimaailma ohtudega toimetulekuks ning analüüsitakse Eesti õpetajate tegevust 9-16aastaste laste internetikasutuse sotsiaalses vahendamises

  3. Die “kerklike gesag” van kerkvergaderings soos in die kerkorde van die Nederduitse Gereformeerde Kerk

    Directory of Open Access Journals (Sweden)

    P. J. Strauss

    2008-07-01

      This means that ecclesiastical authority is founded and based on the Word of God by which it sumultaneously is limited. In exercising it’s authority, an assembly is also bound to do it in accordance with the character of the church. To speak of authority in the church is not in conflict with the character of the church as a community of believers connected by love.

  4. Die selfverstaan van die Samaritane soos dit uit- drukking vind in die feesliturgie צלות מוצד השמיני

    Directory of Open Access Journals (Sweden)

    J. Beyers

    1999-12-01

    Full Text Available The self-understanding of the Samaritans, as expressed in the liturgy of the צלות מוצד השמיני festival This study is concerned with the identity and religion of the Samaritans. The way in which the Samaritans understood their identity is highlighted by their perception of God, by the traditions they adhered to and by the selection of texts from the Pentateuch they used in their liturgy. The beliefs and rituals of the Samarium faith found their way into the Samaritan Liturgy. The study of a part of the Samaritan Liturgy shows that the Samaritans are heirs to the religion of the northern tibes of Israel.

  5. Misdaad in die Suid-Afrikaanse onderwys soos weerspieël in die ...

    African Journals Online (AJOL)

    Erna Kinsey

    Newton, 1989:4; Oosthuizen, 1982:47) blyk dit dat die invloed van die media in die vestiging van persepsies en as inligtingsbron nie onder- skat moet word nie, ..... troniese klok en twee handklokke, 'n skoolhoof se briewetas, sport- toerusting, onderrighulpmiddels, skryfbehoeftes, deure (by 'n skool is daar een nag twaalf ...

  6. Observations of a thin near surface layer in an estuarine environment: An exceptional bloom of the dinoflagellate Akashiwo sanguinea in the Lee estuary (Lough Mahon), Co. Cork, in September 2010

    Science.gov (United States)

    O'Boyle, Shane; McDermott, Georgina

    2014-03-01

    Observations on the occurrence of an exceptional phytoplankton bloom in the Lee estuary, Co. Cork, in September 2010 are reported. A thin layer of phytoplankton dominated by the dinoflagellate Akashiwo sanguinea (Dinophyceae), with a cell concentration of 16,900 cells ml-1 and chlorophyll a concentration of 680 μg l-1, was observed at a depth of 1 m. The layer extended over a horizontal distance of 3 km and was located in the estuarine pycnocline. Levels of dissolved oxygen supersaturation were elevated at 190 (%) saturation (15.9 mg O2 l-1) and the highest biochemical oxygen demand associated with the bloom was greater than 25 mg O2 l-1. Using biovolume data to calculate carbon content, and a water exchange rate of 0.06 d-1 and dilution factor of 0.1, the potential oxygen demand following bloom collapse was estimated to be 7.22 mg O2 l-1. The potential impact of this thin layer on the water quality of the estuary is discussed.

  7. Variações nos níveis das células sangüíneas periféricas encontradas em Holochilus brasiliensis nanus Thomas, 1897, infectados com Schistosoma mansoni Sambon, 1907, próprio da Pré-Amazônia Variations in peripheral blood cell levels examined in Schistosoma mansoni - infected Holochilus brasiliensis nanus Thomas, 1897, from lower Amazonia, Brazil

    Directory of Open Access Journals (Sweden)

    Othon de Carvalho Bastos

    1985-10-01

    Full Text Available Foram constituídos quatro grupos de roedores silvestres para a contagem de células sangüíneas periféricas, da seguinte forma: Grupo I - formado de animais normais, nascidos em biotério, com 30 dias de vida; Grupo II - formado de animais que foram capturados no campo e considerados não infectados com S. mansoni, após ovohelmintoscopia das fezes, realizada durante 30 dias de observação; Grupo III - animáis capturados no campo, nautralmente infectados com o esquistossomo, e o Grupo IV - de animais nascidos em biotério, com 30 dias de vida, e infectados com 150 cercárias de S. mansoni, oriundas da Região da Baixada Maranhense. Semanalmente, a partir da data da infecção, estes animais foram sangrados e tiveram suas células sangüíneas periféricas contadas global e especificamente. Os resultados mostraram que o número de hemácias e leucócitos por mm³ não variou nos animais normais, tanto de campo como de biotério. No grupo de animais experimentalmente infectados, foi observado decréscimo do número de hemácias à proporção que a infecção evoluia. Comportamento oposto foi verificado com os leucócitos. Elevados níveis de eosinófilos só foram observados nos animais com infecção natural. Estes resultados foram discutidos com dados da literatura e considerados importantes para complementar as informações sobre este hospedeiro natural do trematódeo, oferecido como modelo experimental do verme, e para sua própria história natural.Holochilus brasiliensis nanus is a rodent, native to the State of Maranhão, Brazil, which is frequently found when captured to be infected and diseased wich Schistosoma mansoni. It is therefore a useful animal model for experimental studies on schistosomiasis. Studies on the peripheral blood counts in four groups of these rodents are reported. The blood counts of uninfected wild (Group 1 and uninfected laboratory-reared rodents (Group 2 were not found to differ. The laboratory

  8. Hábito alimentar, níveis de lipídios sangüíneos e o status antioxidante de adultos jovens fumantes e não fumantes Food habits, blood lipid levels and antioxidant status of young adults smokers and non-smokers

    Directory of Open Access Journals (Sweden)

    Ellencristina da Silva Batista

    2009-06-01

    Full Text Available OBJETIVO: Avaliar o hábito alimentar, os níveis dos lipídios sangüíneos e o status antioxidante de jovens fumantes e não fumantes. MÉTODOS: Trata-se de um estudo transversal em que 68 indivíduos, de 18 a 26 anos, emparelhados por sexo e idade, foram divididos em dois grupos: fumantes (n=34 e não fumantes (n=34. Os voluntários selecionados em instituições de ensino, em Viçosa (MG foram questionados quanto a: hábito de fumar, consumo de bebidas alcoólicas e atividade física; também foi estimada a dependência nicotínica. O hábito alimentar foi avaliado por questionário de freqüência de consumo. Quantificaram-se níveis séricos de lipídios, nível plasmático de malondialdeído, vitamina E e vitamina C. RESULTADOS: Os jovens começaram a fumar precocemente, independentemente do sexo. O hábito de fumar foi estratificado e encontrou-se 58,8% de fumantes leves e 41,2% de fumantes pesados. Os fumantes apresentaram hábitos alimentares inadequados e consumo freqüente de bebida alcoólica. De acordo com a recomendação do International Physical Activity Questionnaire 69% dos fumantes eram ativos e 27,6% eram muito ativos. Não se observou diferença significante na concentração sérica de lipídios entre fumantes e não fumantes. No grupo de fumantes mulheres, verificou-se correlação positiva entre o número de cigarros fumados por dia e os triglicerídeos séricos (r=0,824 e p=0,0001 e também entre o tempo que fumavam em anos e o nível de colesterol total (r=0,523 e p=0,031. Os fumantes apresentaram concentração inferior de vitaminas E e C (p=0,002 e p=OBJECTIVE: The objective was to evaluate the food habits, blood lipid levels and antioxidant status of young adult smokers and non smokers. METHODS: This cross-sectional study divided 68 individuals aged 18 to 26 years, matched for age and sex, into two groups: smokers (n=34 and non-smokers (n=34. The individuals, selected from schools in Viçosa (MG, were asked about

  9. Lightcurve Results for 1318 Nerina, 222 Lermontov 3015 Candy, 3089 Oujianquan, 3155 Lee, 6410 Fujiwara, 6500 Kodaira, (8290) 1992 NP, 9566 Rykhlova, (42923) 1999 SR18, and 2001 FY

    Science.gov (United States)

    Clark, Maurice

    2007-03-01

    Lightcurve period and amplitude results for 10 minor planets are presented. The observations were made at 3 locations: the Montgomery College Observatory, Chiro Observatory, and the Rosemary Hill Observatory. (1318) Nerina: 2.536 ± 0.001 hr, 0.16 ± 0.02 mag. (2222) Lermontov: 4.344 ± 0.001 hr, 0.58 ± 0.01 mag. (3015) Candy: 4.265 ± 0.001 hr, 1.05 ± 0.01 mag. (3089) Oujianquan: 11.198 ± 0.003 hr, 0.45 ± 0.05 mag. (3155) Lee: 8.36 ± 0.01 hr, 0.4 ± 0.1 mag. (6410) Fujiwara: 7.008 ± 0.001 hr, 0.80 ± 0.02 mag. (6500) Kodaira: 5.496 ± 0.009 hr, 0.80 ± 0.02 mag. (8290) 1992 NP: 4.453 ± 0.001 hr, 0.58 ± 0.02 mag. (9566) Rykhlova: 8.800 ± 0.001 hr, 0.95 ± 0.02 mag. (42923) 1999 SR18: 8.392 ± 0.001 hr, 1.38 ± 0.05 mag. 2001 FY: 5.207 ± 0.005 hr, 0.45 ± 0.05 mag. Also reported are indefinite period results for four objects in the hope that they may be useful for future observers: 1110 Jaroslawa, 1720 Neils, 3872 Akirafuji, and 6790 Pingouin.

  10. Inglased puhkavad Haljalas toodetud patjadel / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2005-01-01

    TOP-i 1. koht. Ülevaade Briti perefirma filiaali, patju ja tekke valmistava Baltic Fibres OÜ tegevusest. Kommenteerib Haljala vallavanem Jüri Sikkut. Lisa: Baltic Fibres OÜ. Diagramm: Kasum 15 miljonit suurem kui mullu

  11. Uued elamupiirkonnad / Lee Taal, Gea Velthut

    Index Scriptorium Estoniae

    Taal, Lee

    1998-01-01

    Lühiinfot: projektijuht, valmis elamud, infrastruktuur, arhitektuurne kontseptsioon, ehitajad, arhitektid jm. Maarjamäe elamupiirkond (AB Harmin, AB Urbel ja Peil, Alver Trummal Arhitektid), Vabaõhukooli tee asum (Künnapu & Padrik), Lepiku küla Kloostrimetsas /Lepiku Kinnisvarahooldus), Raudalu asum Viljandi mnt. ääres (R-Konsult, I. Raud), Kodu 2001 (Nordprojekt, Jaak Kruusmägi), Tiskre Haaberstis (Arhitektuuribüroo Alis), Randvere tee (Nordprojekt), Veskimöldre (Koot ja Koot).

  12. Kahanev rahvaarv kasvatab rahumeelsust / Lee Kuan Yew

    Index Scriptorium Estoniae

    Lee Kuan Yew, 1923-

    2013-01-01

    Singapuri kauaaegne peaminister meenutab, et teise maailmasõja ajendiks oli Jaapani ja Saksamaa kõrgest sündimuskordajast (vastavalt 4,2 ja 2,6) tingitud ruumipuudus ja laienemisiha. Arvestades India (2,6) ja Aafrika riikide (4-7) vastavaid arve, küsib autor, mis meid nüüd ees ootab ja kas oleme selleks valmis

  13. FLOODPLAIN, LEE COUNTY, GEORGIA and INCORPORATED AREAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  14. Lee Kuan Yew: Master Builder of Singapore

    National Research Council Canada - National Science Library

    Exner, Philip J

    1996-01-01

    .... Few, however, have independence forced upon them as Singapore did. On August 9, 1965, after several stormy years attempting to integrate in a post-colonial federation, it was unexpectedly expelled from Malaysia...

  15. ' "Life is Movement": Vernon Lee and Sculpture'

    DEFF Research Database (Denmark)

    Østermark-Johansen, Lene

    2018-01-01

    How do living, breathing human bodies respond to the inert bodies of sculpture? This article examines some of the art-theoretical and psychological writings of Violet Paget (‘Vernon Lee’) and Clementina Anstruther-Thomson of the 1880s and 1890s in an attempt to map the evolution of their formalist...... from Lee’s early essays in Belcaro: Being Essays on Sundry Aesthetical Questions (1881) to the late collaborative volume Art and Man (1924)....

  16. Jaapani edumetoodika ka Eestis / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti 17. nov. lk. 28. Tootmissfääris kasutatavast Jaapani 20 võtme metoodikast loodab ettevõttele kasu saada lehtmetalli töötleva AS-i Favor Metaform nõukogu esimees Almar Proosi. Lisa: Mis on 20 võtit?

  17. DCS Terrain Submission for Lee County MS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix M: Data Capture Standards, describes the digital topographic data that was used to create...

  18. Floodplain Submission for Lee County, MS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  19. THE POLITICAL CRITIQUE OF SPIKE Lee's Bamboozled

    African Journals Online (AJOL)

    Admin

    INTRODUCTION Because slavery is the founding historical relationship between black and white in America many will argue, lingers in subterranean form to this day (Guerrero 1993: 03). Film and the African-American Image. As a form of ..... memory in modern cultural life” (01). Film becomes a cultural tool bearing popular ...

  20. Lee Kuan Yew: Master Builder of Singapore

    National Research Council Canada - National Science Library

    Exner, Philip J

    1996-01-01

    ... powerhouse has made the "Singapore Model" one of the most closely studied patterns among developing nations. Singapore enjoyed sustained growth and political stability during a period when other regional states experienced much turbulence...

  1. Lees- en spellingagterstande van leerders met serebrale ...

    African Journals Online (AJOL)

    The causes and characteristics of the reading and spelling deficits of learners with cerebral palsy (CP), as well as the working memory processing are discussed. Due to the vision, hearing and speech disabilities of these learners, the phonological loop in the working memory receives and rejects an unclear message, ...

  2. African Journal of Biotechnology - Vol 11, No 85 (2012)

    African Journals Online (AJOL)

    Assessment of endophytic fungi cultural filtrate on soybean seed germination · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Muhammad Waqas, Abdul Latif Khan, Muhammad Hamayun, Muhammad Kamran, Sang-Mo Kang, Yoon-Ha Kim, In-Jung Lee, 15135- ...

  3. Amino acids analysis during lactic acid fermentation by single strain ...

    African Journals Online (AJOL)

    SAM

    2014-07-09

    Jul 9, 2014 ... Amino acids analysis during lactic acid fermentation by single strain cultures of lactobacilli and mixed culture starter made from them. KiBeom Lee1*, Ho-Jin Kim1 and Sang-Kyu Park2. 1Bio Center Technopark, 7-50 Songdo, Yeonsu-Gu, Incheon 406-840, Republic of Korea. 2Nambu University, Chumdan ...

  4. Small angle neutron scattering study of doxorubicin–surfactant ...

    Indian Academy of Sciences (India)

    [2] G S Kwon and K Kataoka, Adv. Drug Delive. Rev. 16, 295 (1995). [3] Hyuk Sang Yoo, Eun Ah Lee and Tae Gwan Park, J. Control Release 82, 17 (2002). [4] Tatiana K Bronich, Andrew Nehls, Adi Eisenberg, Victor A Kabanov and Alexander. V Kabanov, Colloids and Surfaces B16, 243 (1999). [5] K Kataoka, T Matsumoto, ...

  5. Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.

    Science.gov (United States)

    Bohacek, R S; McMartin, C

    1992-05-15

    The accessible surface, described by Lee and Richards (the L&R surface: J. Mol. Biol. 1971, 55, 379), has remarkably useful properties for displaying ligand-protein interactions. The surface is placed one van der Waals radius plus one probe radius away from the protein atoms. The ligands are displayed in skeletal form. With a suitable probe radius, those parts of the ligand in good van der Waals contact with the protein binding site are found superimposed on the L&R surface. Display of the surface using parallel contours therefore provides a very powerful guide for interactive drug design because only ligand atoms lying on or close to the surface are in low-energy contact. The ability of the surface to accurately display steric complementarity between ligands and proteins was optimized using data from small molecule crystal structures. The possibility of displaying the chemical specificity of the binding site was also investigated. The surface can be colored to give precise information about chemical specificity. Electrostatic potential, electrostatic gradient, and distance to hydrogen-bonding groups were tested as methods of displaying chemical specificity. The ability of these methods to describe the complementarity actually observed in the interior of proteins was compared. High-resolution crystal data for ribonuclease and trypsin was used. The environment surrounding extended peptide chains in the protein was treated as a virtual binding site. The peptide chain served as a virtual ligand. This large sample of experimental data was used to measure the correlation between type of ligand atom and the calculated property of the nearest binding site surface. The best correlation was obtained using hydrogen-bonding properties of the binding site. Using this parameter the surface could be divided into three separate zones representing the hydrophobic, hydrogen-bond-acceptor, and hydrogen-bond-donor properties of the binding site. The percentage of hydrophobic ligand

  6. Effect of self-assembled peptide–mesenchymal stem cell complex on the progression of osteoarthritis in a rat model

    Directory of Open Access Journals (Sweden)

    Kim JE

    2014-05-01

    Full Text Available Ji Eun Kim,1 Sang Mok Lee,2 Soo Hyun Kim,1 Phil Tatman,3 Albert O Gee,4 Deok-Ho Kim,3,5 Kyung Eun Lee,6 Youngmee Jung,1 Sang Jun Kim21Biomaterials Research Center, Korea Institute of Science and Technology, Seoul, South Korea; 2Department of Physical and Rehabilitation Medicine, Samsung Medical Center, Seoul, South Korea; 3Department of Bioengineering, 4Department of Orthopaedics and Sports Medicine, 5Institute for Stem Cell and Regenerative Medicine and Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA; 6Advanced Analysis Center, Korea Institute of Science and Technology, Seoul, South KoreaPurpose: To evaluate the efficacy of mesenchymal stem cells (MSCs encapsulated in self-assembled peptide (SAP hydrogels in a rat knee model for the prevention of osteoarthritis (OA progression.Materials and methods: Nanostructured KLD-12 SAPs were used as the injectable hydrogels. Thirty-three Sprague Dawley rats were used for the OA model. Ten rats were used for the evaluation of biotin-tagged SAP disappearance. Twenty-three rats were divided into four groups: MSC (n=6, SAP (n=6, SAP-MSC (n=6, and no treatment (n=5. MSCs, SAPs, and SAP-MSCs were injected into the knee joints 3 weeks postsurgery. Histologic examination, immunofluorescent staining, measurement of cytokine levels, and micro-computed tomography analysis were conducted 6 weeks after injections. Behavioral studies were done to establish baseline measurements before treatment, and repeated 3 and 6 weeks after treatment to measure the efficacy of SAP-MSCs.Results: Concentration of biotinylated SAP at week 1 was not significantly different from those at week 3 and week 6 (P=0.565. Bone mineral density was significantly lower in SAP-MSC groups than controls (P=0.002. Significant differences in terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling staining between the control group and all other groups were observed. Caspase-8, tissue inhibitor of

  7. Putusan Bebas Atas Dakwaan Tindak Pidana Lingkungan Hidup: Analisis Putusan No. 781/pid/b/2009/PN.CBN.

    Directory of Open Access Journals (Sweden)

    Hidayatulloh .

    2016-10-01

    Full Text Available Abstract: Acquittal on Accusation of Environmental Crime: Analysis of Verdict Number No. 781/Pid/B/2009/PN.Cbn. The number of industries has increasead rapidly and caused some problems in the environment. With the help of science and technology, most of industries produce toxic waste which is one of the issues of the environmental crime. This paper will analyse the verdict of Cibinong District Court on accusation of environmental crime to Lee Sang Book, the Director of PT. Roselia Texindo. The company working in textile industry was indicted that he has done water pollution in the River Cikuda, Bogor because he has thrown the toxic waste to the river produced by its industry. The verdict is really interesting because the panel of judges have finally decided that Lee Sang Book is not guilty. Based on facts of the trial, he doesn’t break a law to do the environmental crime which was indicted according to the Law Number 23 Year 2007 in Living Environment. Cibinong District Attorney has submitted the unqualified evidence in examination of waste toxic in laboratorium. Furthermore most witnesses and expert witnessed have argued that Lee Sang Book and PT. Roselia Texindo are innocence and have followed the rule. Abstrak: Jumlah industri telah meningkat dengan cepat dan menyebabkan beberapa persoalan lingkungan. Dengan dukungan ilmu pengetahuan dan teknologi, banyak industri menghasilkan limbah berbahaya yang merupakan salah satu isu tindak pidana lingkungan. Tulisan ini menganalisis putusan Pengadilan Negeri Cibinong atas dakwaan tindak pidana lingkungan kepada Lee Sang Book, Direktur PT. Roselia Texindo. Perusahaan yang bergerak di bidang tekstil ini didakwa melakukan pencemaran air sungai Cikuda, Bogor karena membuat limbah kimia hasil proses industri. Pada akhirnya Majelis Hakim memutus bahwa Lee Sang Book tidak bersalah. Berdasarkan fakta-fakta persidangan, ia tidak terbukti melakukan tindak pidana lingkungan yang didakwakan berdasarkan Undang

  8. E. S. M ulder . Ds. S. H oekstra , Het Boek Leviticus. J. H . Kok, N. V. ...

    African Journals Online (AJOL)

    Test

    14:10 lees ons van een volkomen schaap van een jaar oud, Hoekstra omskryf dit as een een-jarig vrouwtjesschaap, die N.B.G. een eenjarige gave ooi. Soms kry ons minder juiste omskrywings b.v. in Lev. 26:13, waar sprake is nie van die verbreking van die juk soos die skrywer wil nie, maar van die jukskeie. Die inhoud ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Polyopes affinis alleviates airway inflammation in a murine model of allergic asthma. Dae-Sung Lee Won Sun Park Soo-Jin Heo Seon-Heui Cha Daekyung Kim You-Jin Jeon Sae-Gwang Park Su-Kil Seo Jung Sik Choi Sung-Jae Park Eun Bo Shim Il-Whan Choi Won-Kyo Jung. Articles Volume 36 Issue 5 December 2011 pp ...

  10. Transfusão sangüínea em crianças e os métodos para evitá-la: uma reavaliação Transfusión sanguínea en niños y los métodos para evitarla: una reevaluación Blood transfusion in pediatric patients and strategies to decrease it: a reevaluation

    Directory of Open Access Journals (Sweden)

    Mário José da Conceição

    2004-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Muitas medidas e técnicas são utilizadas, nos pacientes adultos, na tentativa de reduzir, ou evitar, tanto a perda sangüínea como a administração de sangue homólogo durante atos cirúrgicos para os quais se esperam grandes perdas na volemia. Enquanto as estratégias para evitar a utilização de sangue homólogo em pacientes adultos são largamente empregadas, nos pacientes pediátricos são negligenciadas. Talvez isso se deva ao fato de que em crianças essas técnicas podem não ser tão úteis quanto nos adultos, além dos problemas técnicos próprios do tamanho dos pacientes. O objetivo dessa revisão foi reavaliar as técnicas para reduzir a necessidade de transfusão de sangue homólogo em adultos e discutir sua utilização em pacientes pediátricos. CONTEÚDO: Através da pesquisa bibliográfica apresentam-se às estratégias mais freqüentes para diminuir, ou mesmo evitar, transfusão de sangue homólogo durante atos cirúrgicos nos quais esperam-se grandes perdas volêmicas. Como todos os métodos conhecidos foram desenvolvidos para pacientes adultos, projeta-se, a partir daí, reavaliando-se esses métodos, técnicas e fármacos, uma linha de ação visando a sua aplicabilidade nos pacientes pediátricos. CONCLUSÕES: Mais uma vez fica patente que as soluções obtidas para adultos não são aplicáveis inteiramente aos pacientes pediátricos. As medidas para reduzir o sangramento intra-operatório e a conseqüente redução na necessidade do emprego de sangue homólogo são eficientes em pacientes adultos, porém são de longe mais invasivas, complicadas e muitas delas ineficientes nos pacientes pediátricos, notadamente naqueles abaixo de dois anos de idade.JUSTIFICATIVA Y OBJETIVOS: Muchas medidas y técnicas son utilizadas, en pacientes adultos, en la tentativa de reducir, o evitar, tanto la pérdida sanguínea como la administración de sangre homólogo durante actos quirúrgicos para los cuales

  11. Karistusseadustiku § 119¹ ehk tõenduslike probleemide ületamine materiaalõiguse abil / Anneli Soo, Birgit Sisask

    Index Scriptorium Estoniae

    Soo, Anneli, 1984-

    2015-01-01

    1. jaanuaril 2015 jõustus karistusseadustikus rida muudatusi, sh lisandus § 119¹, mis käsitleb kakluses osalemist. Karistusõiguslikest ja põhiseaduslikest põhimõtetest, millega § 119¹ läheb vastuollu

  12. A fixed-dose combination tablet of gemigliptin and metformin sustained release has comparable pharmacodynamic, pharmacokinetic, and tolerability profiles to separate tablets in healthy subjects

    Directory of Open Access Journals (Sweden)

    Park SI

    2015-02-01

    Full Text Available Sang-In Park,1,* Howard Lee,1,2,* Jaeseong Oh,1 Kyoung Soo Lim,3 In-Jin Jang,1 Jeong-Ae Kim,4 Jong Hyuk Jung,4 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Clinical Trials Center, Seoul National University Hospital, Seoul, 3Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine and CHA Bundang Medical Center, Seongnam, 4LG Life Sciences, Ltd, Seoul, Republic of Korea *These authors contributed equally to this work Background: In type 2 diabetes mellitus, fixed-dose combination (FDC can provide the complementary benefits of correction of multiple pathophysiologic defects such as dysfunctions in glycemic or metabolic control while improving compliance compared with separate tablets taken together. The objective of the study reported here was to compare the pharmacodynamic (PD, pharmacokinetic (PK, and tolerability profiles of gemigliptin and extended-release metformin (metformin XR between FDC and separate tablets.Methods: A randomized, open-label, single-dose, two-way, two-period, crossover study was conducted in 28 healthy male volunteers. Two FDC tablets of gemigliptin/metformin 25/500 mg or separate tablets of gemigliptin (50 mg ×1 and metformin XR (500 mg ×2 were orally administered in each period. Serial blood samples were collected up to 48 hours post-dose to determine dipeptidyl peptidase 4 (DPP-4 activity using spectrophotometric assay and concentrations of gemigliptin and metformin using tandem mass spectrometry. Geometric mean ratios (GMRs of FDC to separate tablet formulations and their 90% confidence intervals (CIs were calculated to compare the PD and PK parameters between the two formulations. Tolerability was assessed throughout the study.Results: The plasma DPP-4 activity

  13. Uudised : Hortus Musicus Moskvas. TPÜ naiskoor koorikonkursil. RAM samal laval Mark Knopfleriga. "Tuuleveskid. Kerkokell" / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2000-01-01

    Hortus Musicus esines 23. ja 24. nov. Moskvas. TPÜnaiskoor võitis II preemia XVII rahvusvahelisel F.Schuberti nim. koorikonkursil Austrias. RAM esineb 8. dets. Helsingis Hartwall Areenas heategevuskontserdil. RAM esineb 6. dets. Estonia kontserdisaalis kavaga "Tuuleveskid. Kerkokell"

  14. Mellem næstsidste sang og offerdød

    DEFF Research Database (Denmark)

    Bonde, Lars Ole

    2010-01-01

    Anmeldelse af Ruders' nye opera Dancer in the Dark, som havde urpremiere på Operaen, DKT, i september 2010.......Anmeldelse af Ruders' nye opera Dancer in the Dark, som havde urpremiere på Operaen, DKT, i september 2010....

  15. Sange fra Vestkysten – en overset side af populærmusikken i Danmark

    Directory of Open Access Journals (Sweden)

    Niels Kayser Nielsen

    2011-06-01

    Full Text Available Det vestjyske musikmiljø, på kysten fra Grænsen til Skagen, henlever en stille tilværelse i den danske kulturelle offentlighed og er med enkelte markante undtagelser næsten ukendt på den populærkulturelle musikscene. Denne artikel er et forsøg på at give mæle til et populærkulturelt marginalområde af Danmark; ikke for at placere det i en offerrolle, men snarere for at komplettere billedet af dansk musikkultur ved at pege på en center/periferi-tilgang. Nærmere bestemt foretages der analyser af de tematikker – kærlighed, politik, arbejde, kristentro, hjemstedsfornemmelse – der er så fremtrædende i den vestjyske musikkultur. Det er en grundtanke, at en opmærksomhed på også denne del af dansk musikliv er ønskværdig i henseende til udformningen af et kulturelt demokrati med henblik på en ligeværdig anerkendelse. 

  16. Séroprévalence du cytomégalovirus chez les donneurs de sang au ...

    African Journals Online (AJOL)

    Objective: The aim of this study was to determine the seroprevalence of CMV-IgG and CMV-IgM among voluntary blood donors in national centre of blood transfusion (CNTS) of Lomé, main town of Togo, West Africa. This is a view to making recommendations on donor screening and transfusion protocols among susceptible ...

  17. Gaya Bahasa Dalam Novel Terjemahan Sang Pengejar Layang-layang (the Kite Runner) Karya Khaled Hosseini

    OpenAIRE

    Maya Setia Ekawati, Dian; Sumarwati, Sumarwati; Anindyarini, Atikah

    2012-01-01

    The purpose of this research is : (1) to describes the dominant language of style is use by Khaled Hosseini in the translation novel The Kite Runner, and (2) perception readers againt the used language of style in novel. The sampling technique used was purposive sampling. Data collection techniques used were in-depth interviews and document analysis. Data analysis technique used is the interactive analytical model that includes four components, namely data collection, data reduction, data pre...

  18. Don de sang de cordon : vécu, information et motivations des sages-femmes

    OpenAIRE

    Sanon, Sandy

    2011-01-01

    The cord blood is a recognized source of stem cells. The expansion of the French network gives midwives a prominent place at different stages of this gift. Responsiveness, knowledge of midwives on the DSC and the impact of the introduction of the latter in the delivery room were evaluated. Through a multicentric study by questionnaire. A questionnaire is designed for midwives practicing the DSC and a second to those working in maternity wards without DSC. It is remarkable that in nearly 100% ...

  19. Crème de la crème / Joel Sang

    Index Scriptorium Estoniae

    Sang, Joel, 1950-

    2011-01-01

    Auhinnažürii esimees iseloomustab Eesti Kultuurkapitali kirjandusauhindade laureaate: Indrek Koff (luule), Maarja Kangro (proosa), Urmas Vadi (näitekirjandus), Toomas Haug (esseistika), Lauri Sommer (vabaauhind), Amar Annus (ilukirjanduslik tõlge võõrkeelest eesti keelde), Ilmar Lehtpere (ilukirjanduslik tõlge eesti keelest võõrkeelde), Kristiina Kass (lastekirjandus), Sergei Issakov (venekeelse autori kirjandusauhind) ja Mart Velsker (artikliauhind)

  20. Sügis : [luuletused] / Mihhail Lermontov ; tlk. Marie Under, Villem Daniel, August Sang

    Index Scriptorium Estoniae

    Lermontov, Mihhail, 1814-1841

    2006-01-01

    Sisu: Sügis ; Monoloog ; Sõbrale ; Albumisse ; Eleegia ; Kevad ; Üksindus ; Minu maja ; Lained ja inimesed ; Stantsid ; "Kuigi arm on mind hüljanud ammu..." ; "Kui õhtul kaeblik leinakell..." ; Kuulsus ; "Võib-olla meenutad kord mind..." ; Ingel ; Romanss J...le ; "Kord saabub päev, kui kõigi süüdistatud..." ; "Kus mühavad Dnepri jõe rahutud vood..." ; "Mull̀ armas sinimägi-voor..." ; "Su ees ei saa ma alanduma..." ; Epitaaf ; "Ei, Byron, see ei ole ma..." ; "Aeg on südamele vaga..." ; "Ma õnne taevastelt ei palu..." ; Poeedi surm ; Vang ; Naaber ; "Kui kollendavad põllud lainetavad valla..." ; "Ma leidsin teise kaunitari..." ; "Ei taha, et mu saladust..." ; Poeet ; Ära usu end ; A. J. Odojevski mälestuseks ; Kolm palmi ; Palve ; Testament ; "Nii tihti pidudel, kus kirju hulk on koos..." ; Miks ; On igav ja kurb ; M. A. Shtsherbatovale ; Õhulaev ; Lapsele ; Pilved ; "Poolmaski alt täis saladust ja külma..." ; Kalju ; "Astun üksipäini oma rada..." ; Prohvet ; Leping ; "Ei, mitte sind ei imetle ma nii..." ; Puri. Eluloolisi andmeid autori kohta lk. 575

  1. Faust. Pühendus : [luuletused] / Johann Wolfgang von Goethe ; tlk. Marie Under, August Sang

    Index Scriptorium Estoniae

    Goethe, Johann Wolfgang von, 1749-1832

    2006-01-01

    Sisu: Faust. Pühendus ; Aardekaevur ; Cophta laul ; Hall sompus hommik ; Thule kuningas ; Kohtumine ja hüvastijätt ; Mailaul ; "Ma koltund väljadele rühin ; Retsensent ; Kannike ; Christel ; Kunstniku õhtulaul ; Uus armastus, uus elu ; Lottchenile ; Järvel ; Mäelt ; Amulett ; Ränduri öölaul : "Kes sa tead, oh taevane..." ; Meresõit ; Julgustus ; Kirjast Auguste zu Stolbergile ; Kuule ; Manitsus ; Inimsoo piirid ; Vaimude laul vete kohal ; Ränduri öölaul : "Harjadel püha..." ; Öömõtted ; Metsavaim ; Kandlemängija : "Kes pole leiba söönud, silmad vees..." ; Reisivarustus ; Jumalik ; Mignon : "Kas maad sa tead, kus apelsinipuul..." ; Pühendus ; Charlotte von Steinile ; Esimene kaotus ; Külaskäik ; Ketraja ; Mignon : "Miks vastust nõuad? Vaikida mul lase..." ; Kandlemängija : "Uste taha hiilin sala..." ; Armastatu lähedus ; Mignon : "Et ükskord olla, pean ma näima..." ; Lahkumine ; Kestvus vahelduses ; Aastad ; Õnnis igatsus ; Märts ; Rännulaul ; Parabaas ; Üks ja kõik ; Testament

  2. Uudised : Ilmub eesti kammermuusika album. RAM ja Jaan-Eik Tulve. TÜ naiskoor 55 / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2000-01-01

    ER poolt välja antud eesti kammermuusika albumist "Significatio", mille esitlus toimub 17. märtsil Assauwe tornis. 11. märtsil Pärnus ja 15. märtsil Viljandis toimunud RAMi kontsertidest, juhatas J.-E. Tulve. 4. märtsil alustas TÜ naiskoor oma 55. sünnipäevale pühendatud kontserdiseeriat. Ilmus ka naiskoori esimene CD-plaat "Tähemõrsja", millel V. Tormise naiskoorimuusika

  3. Editorial: Latest methods and advances in biotechnology.

    Science.gov (United States)

    Lee, Sang Yup; Jungbauer, Alois

    2014-01-01

    The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Convenient synthetic method of starch/lactic acid graft copolymer ...

    Indian Academy of Sciences (India)

    Cho and Lee 2002; Zhai et al 2002; Fanta et al 2004) can improve the ... aliphatic polyester (Sang et al 1997; Choi et al 1999; Dubois et al 1999) are a .... Chemical shift /ppm. 5.50. 5.40 4.59. 3.60~3.40. (A). DMSO. Figure 4. 1H-NMR spectra of cornstarch (A) and starch/LA copolymer (B). HO. OH. CH3. O. O. H. O. HO. H. OH.

  5. Protection of Mission-Critical Applications from Untrusted Execution Environment: Resource Efficient Replication and Migration of Virtual Machines

    Science.gov (United States)

    2015-09-28

    for VM clusters running ho - mogeneous workloads, especially when VMs in the cluster collaborate on a shared task set. In these scenarios, similarity...Proceedings of the 3rd ACM European Conference on Computer Systems, 2008. [68] Changwoo Min, Kangnyeon Kim, Hyunjin Cho , Sang-Won Lee, and Young Ik Eom. SFS...2015. 3. Karen Hou, Kang G. Shin, and Jan-Lung Sung , ``Application-Assisted Live Migration of Virtual Machines with Java Applications,’’ ACM EuroSys

  6. In-situ Manipulation and Imaging of Switchable Two-dimensional Electron Gas at Oxide Heterointerfaces

    Science.gov (United States)

    2016-11-30

    ion milling strategy to remove the surface damage layers which are the main cause of the leakage current. After several attempts of optimization...Nonpolar InGaN/GaN Quantum wells”, Ja Kyung Lee, Kyung Song, Christoph T. Koch, Woo Young Jung, Dmitry Tyutyunnikov, Tiannan Yang , Jong Kyu Kim...Chan Gyung Park, Peter A. van Aken, Long-Qing Chen, Young-Min Kim, Sang Ho Oh, submitted to Advanced Functional Materials (2016). f ) provide a

  7. Study guide for Statistics for business and financial economics a supplement to the textbook by Cheng-Few Lee, John C. Lee and Alice C. Lee

    CERN Document Server

    Moy, Ronald L; Kao, Lie Jane

    2015-01-01

    This Study Guide accompanies Statistics for Business and Financial Economics, 3rd Ed. (Springer, 2013), which is a business statistics textbook that uses finance, economics, and accounting data throughout the book. This Study Guide contains unique chapter reviews for each chapter in the textbook, formulas, examples, and additional exercises to enhance topics and their application. Solutions are included so students can evaluate their own understanding of the material. With more real-life data sets than the other books on the market, this study guide and the textbook that it accompanies, give readers all the tools they need to learn material in class and on their own. The topics covered are immediately applicable to facing uncertainty and the science of good decision making in financial analysis, econometrics, auditing, production, operations, and marketing research. Students in business degree programs will find this material particularly useful in their other courses and future work.

  8. Cultura clássica, ópera e literatura na produção juvenil contemporânea: análise da obra La Traviata, por Lee Gyeong Hye, com ilustrações de Aurelia Fronty

    Directory of Open Access Journals (Sweden)

    Eliane Aparecida Galvão Ribeiro Ferreira

    2016-12-01

    Full Text Available Este texto tem por objetivo apresentar uma análise da obra La Traviata, adaptada por Lee Gyeong Hye (2012 e ilustrada por Aurelia Fronty, a partir da ópera clássica homônima de Giuseppe Verdi. Para a consecução do objetivo, busca-se apresentar uma reflexão fundamentada pela Estética da Recepção acerca do que propicia o prazer na leitura e quais elementos determinam o papel do leitor implícito. Constrói-se a hipótese de que a estratégia de Hye de resgatar uma ópera clássica e adaptá-la sob a forma de narrativa ilustrada para o jovem leitor, tanto lhe faculta contato com um texto atraente, lúdico e crítico que o conduzirá à reflexão, quanto amplia seus conhecimentos, por meio do resgate da memória cultural.

  9. A 90-day study of sub-chronic oral toxicity of 20 nm positively charged zinc oxide nanoparticles in Sprague Dawley rats

    Directory of Open Access Journals (Sweden)

    Park HS

    2014-12-01

    Full Text Available Hark-Soo Park,1 Seon-Ju Kim,1 Taek-Jin Lee,1 Geon-Yong Kim,1 EunHo Meang,1 Jeong-Sup Hong,1 Su-Hyon Kim,1 Sang-Bum Koh,1 Seung-Guk Hong,1 Yle-Shik Sun,1 Jin Seok Kang,2 Yu-Ri Kim,3 Meyoung-Kon Kim,3 Jayoung Jeong,4 Jong-Kwon Lee,4 Woo-Chan Son,5 Jae-Hak Park61General Toxicology Team, Korea Testing and Research Institute, Seoul, 2Department of Biomedical Laboratory Science, Namseoul University, Cheonan, 3Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, 4National Institute of Food and Drug Safety Evaluation, Seoul, 5Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 6Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, KoreaPurpose: The study reported here was conducted to determine the systemic oral toxicity and to find the no-observed-adverse-effect level of 20 nm positively charged zinc oxide (ZnOSM,20(+ nanoparticles in Sprague Dawley rats for 90 days.Methods: For the 90-day toxicity study, the high dose was set as 500 mg per kg of body weight (mg/kg and the middle and low dose were set to 250 mg/kg and 125 mg/kg, respectively. The rats were held for a 14-day recovery period after the last administration, to observe for the persistence or reduction of any toxic effects. A distributional study was also carried out for the systemic distribution of ZnOSM,20(+ NPs.Results: No rats died during the test period. There were no significant clinical changes due to the test article during the experimental period in functional assessment, body weight, food and water consumption, ophthalmological testing, urine analysis, necropsy findings, or organ weights, but salivation was observed immediately after administration in both sexes. The total red blood cell count was increased, and hematocrit, albumin, mean cell volume, mean cell hemoglobin, and mean cell hemoglobin concentration were decreased significantly compared with

  10. Método simplificado para manutenção da concentração sangüínea de propofol em nível aproximadamente constante, associado ao óxido nitroso no paciente pediátrico Método simplificado para manutención de la concentración sanguínea de propofol en nivel aproximadamente constante, asociado al óxido nitroso en el paciente pediátrico Simplified method to maintain propofol blood concentration in an approximately constant level associated to nitrous oxide in pediatric patients

    Directory of Open Access Journals (Sweden)

    Pedro Thadeu Galvão Vianna

    2002-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A manutenção de concentração sangüínea alvo-controlada em níveis aproximadamente constantes do propofol é uma técnica que pode ser empregada de modo simplificado na sala de cirurgia. A finalidade desta pesquisa é comparar clínica e laboratorialmente a infusão de propofol em crianças usando os atributos farmacocinéticos de Short e de Marsh. MÉTODO: Foram estudados 41 pacientes com a idade de 4 a 12 anos, de ambos os sexos, estado físico ASA I ou II, distribuídos em dois grupos S (20 pacientes e M (21 pacientes. No Grupo S utilizaram-se os atributos farmacocinéticos de Short, e no Grupo M, os atributos farmacocinéticos de Marsh. A indução anestésica foi feita com bolus de alfentanil 30 µg.kg-1, propofol 3 mg.kg-1 e pancurônio, 0,08 mg.kg-1 por via venosa. Procedeu-se a intubação traqueal e a manutenção com N2O/O2 (60% em ventilação controlada mecânica. No grupo S a infusão de propofol foi de 254 (30 min seguido de 216 µg.kg-1.min-1 por mais 30 min. No grupo M a infusão de propofol foi de 208 (30 min seguido de 170 µg.kg-1.min-1 por mais 30 min. Através do atributo farmacocinético específico a cada grupo a meta foi a obtenção da concentração-alvo de 4 µg.kg-1 de propofol. Foram colhidas três amostras sangüíneas (aos 20, 40 e 60 minutos para a dosagem do propofol pelo método da Cromatografia Líquida de Alta Performance. RESULTADOS: Os Grupos S e M foram considerados similares quanto à idade, altura, peso e sexo (p > 0,05. Não houve diferença estatística significativa entre os dois grupos estudados para os parâmetros: PAS, PAD, FC, FiN2O, SpO2 da hemoglobina e P ET CO2 no final da expiração. A comparação entre grupos no número de bolus repetidos de alfentanil não foi estatisticamente significativa. O índice bispectral (BIS não apresentou diferença estatisticamente significativa entre M0 (vigília e os demais momentos em ambos os grupos. Os valores Medianos da

  11. Valores hematológicos e identificação morfo-citoquímica de células sangüíneas de capivaras (Hydrochoerus hydrochoeris parasitadas por carrapatos e capivaras livres de infestação - DOI: 10.4025/actascianimsci.v25i1.2116 Hematological values and morpho-cytochemical blood cells identification of tick parasited capybaras (Hydrochoerus hydrochoeris and capybaras free of parasitism - DOI: 10.4025/actascianimsci.v25i1.2116

    Directory of Open Access Journals (Sweden)

    Antenor Aguiar Santos

    2003-04-01

    Full Text Available Amostras de sangue foram colhidas de 37 capivaras parasitadas por carrapatos e de 21 capivaras livres de infestação para a identificação dos diferentes tipos celulares circulantes e para realização de hemograma. Após análise morfológica, as células sangüíneas foram identificadas como heterófilos, eosinófilos, basófilos, linfócitos, monócitos e plaquetas. A reação de PAS demonstrou glicogênio no citoplasma dos heterófilos e plaquetas. Reação positiva para mieloperoxidase e lipídeos foi demonstrada apenas nos grânulos citoplasmáticos esféricos dos heterófilos e em todos os grânulos citoplasmáticos dos eosinófilos. O método do azul de bromofenol revelou reação fortemente positiva nos grânulos de heterófilos, eosinófilos, basófilos e nas hemácias. Reação positiva para fosfatase alcalina foi observada nos heterófilos e eosinófilos. Os valores hematimétricos que mostraram diferenças estatisticamente significantes (p6/µL e 2,81±0,62 x 106/µL, hematócrito (48.14±4.75% e 41,22±6.21%, e, na contagem diferencial, os heterófilos (39,38±11,02% e 16,14±7,13% e, eosinófilos (8,57±3,78% and 21,92±10,24%. Os carrapatos foram identificados como Amblyomma cajenense and Amblyomma cooperi. As capivaras altamente infestadas por esses carrapatos apresentaram anemia e uma eosinofilia marcante.Blood samples were collected from thirty seven adult parasited capybaras and twenty one free of parasitism aiming the characterization of different circulating cell types and complete hemogram. After a morphological analysis, the blood cells were identified as heterophils, eosinophils, basophils, lymphocytes, monocytes and platelets. The PAS reaction revealed glycogen in heterophils and platelets cytoplasm. A positive reaction was found only in heterophils round granules and in all cytoplasmic granules of eosinophils for the demonstration of myeloperoxidase activity and lipids. The bromofenol blue method revealed strong

  12. Multiple mortality modeling in Poisson Lee-Carter framework

    OpenAIRE

    D'Amato, V.; Haberman, S.; Piscopo, G.; Russolillo, M.; Trapani, L.

    2016-01-01

    The academic literature in longevity field has recently focused on models for detecting multiple population trends (D'Amato et al., 2012b; Njenga and Sherris, 2011; Russolillo et al., 2011, etc.). In particular, increasing interest has been shown about "related" population dynamics or "parent" populations characterized by similar socioeconomic conditions and eventually also by geographical proximity. These studies suggest dependence across multiple populations and common long-run relationship...

  13. Die ontwikkeling van die ESSI-lees- en speltoets | Esterhuyse ...

    African Journals Online (AJOL)

    The ESSI reading and spelling test (Afrikaans and English) was developed to replace the well-known UCT reading and spelling test standardized in 1944. This measuring instrument was developed in four phases. This article deals with the development work performed during the first three phases. During phase 1, support ...

  14. Die ontwikkeling van lees- en speltoetse vir Sesotho-sprekende ...

    African Journals Online (AJOL)

    In this study, a reading and spelling test for the Sesotho-speaking learners in the elementary phase was developed and standardised. A Sesotho reading and spelling test was developed, which could be used to determine the reading and spelling skills of Grades 1–3 learners. The test indicated norms per quarter and could ...

  15. Psigometriese eienskappe van die ESSI-lees- en speltoets ...

    African Journals Online (AJOL)

    In drawing up the ESSI reading and spelling test, four phases were followed. In an earlier article, the development work that took place during the first three phases was discussed. This article focuses on the last phase during which the psychometric characteristics of the ESSI reading and spelling test were investigated.

  16. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, LEE COUNTY, FLORIDA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  17. Developing effective supervisors: Concepts of research | Lee | South ...

    African Journals Online (AJOL)

    Educating our early career researchers is becoming more complex. The range of doctoral degrees, the fast moving nature of knowledge, internationalisation, the demands of funding bodies and employers are all pulling on Ph.D. supervisors. The untrained Ph.D. supervisor will copy (or avoid copying) the way that they were ...

  18. Multiple myeloma in an Amur tiger ( Panthera tigris altaica ) | Lee ...

    African Journals Online (AJOL)

    The Amur tiger (Panthera tigris altaica) is an endangered tiger subspecies. An adult zoo-bred female was found collapsed, and died despite supportive treatment. Hematology and biochemistry showed pancytopenia and hyperglobulinemia, and serum protein electrophoresis revealed a monoclonal band in the β-globulin ...

  19. Book Review: Hospital and nursing yearbook | Lee | South African ...

    African Journals Online (AJOL)

    Abstract. Book Title: Hospital and nursing yearbook: Hospital and Nursing Yearbook for Southern Africa: Comprehensive Health Services Information for Southern Africa. 32nd ed. pp. 288. Cape Town: H. Engelhardt. 1992.

  20. Matthew's community and the Gentile mission / by Kukzin Lee

    OpenAIRE

    Lee, Kukzin

    2010-01-01

    Matthew contains seemingly contradictory passages with regard to the Gentiles and the Gentile mission. On the one hand, it seems that the Gentiles are disparaged and excluded from the missionary activities of Jesus' disciples. On the other hand, some Matthean passages imply the Matthean community's open attitude toward the Gentiles. Scholars have stressed one part of evidence over the other and come to the conclusion that either Matthew's community was extra muros or intra muros, respectively...

  1. Application of biologics to feedstuff | Lee | African Journal of ...

    African Journals Online (AJOL)

    ... transformed enzyme gene or raw material of feedstuff using biotechnology (e.g. fermentation) to enhance nutritive value. However, the availability of these biotechnological products shall be proved by the animal feeding trial. Keywords: Enzyme, feed additives, fermentation, probiotics. African Journal of Biotechnology Vol.

  2. Lees-om-te-leer: 'n studievaardigheid | Esterhuizen | Journal for ...

    African Journals Online (AJOL)

    Learners specially acquire knowledge by means of reading. The importance of this skill is emphasised with reference to reading strategies and the teaching thereof, as well as the development of critical and analytical thinking. Although it is not implicated that such teaching does not exist at all, the lack of a procedural and ...

  3. Kofi Annan und Tim Berners-lee preisen Informationsfreiheit

    CERN Multimedia

    Ermet, Monika

    2003-01-01

    The UN General Secretary and the Pioneer of WEB, will participate in Geneva at the WSIS with scholars from all the world. The World Summit on the Information Society was held in two phases. The first phase took place in Geneva hosted by the Government of Switzerland from 10 to 12 December 2003. It addressed the broad range of themes concerning the Information Society and adopted a Declaration of Principles and Plan of Action

  4. Adaptive Lee enhancement algorithm for processing drop_quality image

    Science.gov (United States)

    Wang, Xinsai; He, Jing; Li, Xue; He, Ming

    2007-12-01

    In order to transform image contrast and enhance vision effect the enhancement processing of image is need in the system of object recognition and automatic target tracking. The methods of image enhancement are more, for example, linearity, line segment, nonlinear, histogram equalization, histogram normalization, power exponent, local gray-level statistic feature and so on. Through analyzing gradient characteristic of image gray-level, in this paper the method of image enhancement is presented based on the local statistic arithmetic of neighborhood grads even. Experiment results show the correctness and utility of this method.

  5. 2014 Lee County, GA DMC 4-Band 8 Bit Imagery

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of six-inch pixel resolution, natural color orthoimages covering the urban area footprint. An orthoimage is remotely sensed image data in...

  6. Lee as Critical Thinker: The Example of the Gettysburg Campaign

    Science.gov (United States)

    2012-05-04

    the preservation of the Union were all at stake. Most scholars agree that in retrospect, the Battle of Gettysburg was one of the turning points in...could prevent reinforcements from the right. Bottom line, the object of the second day was the Peach Orchard and ultimately Cemetery Hill. Contrary...Wheatfield and Peach Orchard were taken but the Union held Little Round Top. Poor coordination and delays were factors in the failure to break through

  7. Een teks - meerdere betekenisse: Hoe lees ons die Bybel?

    Directory of Open Access Journals (Sweden)

    Ernest van Eck

    2008-03-01

    Full Text Available One text – multiple meanings: How do we read the Bible? This article discusses three ways of reading the Bible that are evident in the current theological debate in South Africa: a fundamentalist, foundationalist and critical reading. A brief description and evaluation of the three reading strategies are given. It is indicated that a fundamentalist reading of the Bible essentially operates with a canon in the canon, and a foundationalist reading with a canon outside the canon. A critical reading, which roots can be traced back to the Reformation, is put forward as possibly a more responsible way of reading the Biblical text, especially since it takes cognizance of the historical and cultural distance between text and reader. It is argued that readers who take this “differentness” seriously, are enabled to read the Bible afresh and anew, especially in terms of some burning ethical questions of our day. Attention is also given to a critical reading of metaphorical language of the Bible.

  8. Aspectual auxiliary verbs in Xitsonga | Lee | Stellenbosch Papers in ...

    African Journals Online (AJOL)

    Stellenbosch Papers in Linguistics Plus. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 48 (2015) >. Log in or Register to get access to full text downloads.

  9. 76 FR 30947 - Stephen Lee Seldon: Debarment Order

    Science.gov (United States)

    2011-05-27

    ... convicted of a felony under Federal law for conduct relating to the regulation of any drug product under the... conduct relating to the regulation of a drug product. The factual basis for those convictions is as... felonies under Federal law for conduct relating to the regulation of a drug product under the FD&C Act. The...

  10. Suudab ta pensionäre toita? / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2000-01-01

    Kuna Eesti rahvastiku vananemine suurendab ülalpeetavate hulka ühiskonnas, siis ei saa praegust solidaarsuspõhimõttel rajanevat pensionisüsteemi enam kasutada, vaid tuleb pensionisüsteemi muuta. Pensionisüsteemi koormusest ja kohustuslikust kogumispensionist. Diagrammid: Eesti rahvaarv 1999-2050; rahvastikupüramiid 1997, 2025 ja 2050; kaua saavad/said mehed ja naised pensionipõlve nautida 1960-2010; vajaliku sotsiaalmaksu % palgast 2000-2070; keskmise pensioni ja brutopalga suhe 1965-2000; vanurite osatähtsus 1881-2030; keskmine eluiga 1950-2050. Kommenteerivad E. Nestor, K. Katus, L. Sakkeus

  11. Occipital condylar dysplasia in a Jacob lamb ( Ovis aries ) | Lee ...

    African Journals Online (AJOL)

    multihorned) phenotype. We describe a four-horned Jacob lamb that exhibited progressive congenital hindlimb ataxia and paresis, and was euthanased four weeks post-partum. Necropsy and CT-scan revealed deformity and asymmetry of the ...

  12. Tim Ingold and Jo Lee Vergunst, eds., . Aldershot, Ashgate ...

    African Journals Online (AJOL)

    ANBR

    foregrounding the topic of 'ways of walking', one that is often relegated to footnotes or to short sections on ... Malaysia, who are lowland peoples living close to Malay villages where supplies can be bought and where they ... (slave trade) and contemporary (tourist walking trails and encountering tourists as she walks with the ...

  13. Distribution of conjunctive and disjunctive forms in Xitsonga | Lee ...

    African Journals Online (AJOL)

    Xitsonga follows these basic patterns observed in other Bantu languages, but previous theories cannot explain all of the cases in which the conjunctive and disjunctive forms are distinguished. In previous work, three major approaches have been proposed: the constituency approach, the focus-based approach, and the ...

  14. Diamond Jubi lee of the Academy Mid-Year Meeting

    Indian Academy of Sciences (India)

    1994-07-01

    Jul 1, 1994 ... The lecturer began by characterizing their work as a clock comparison experiment leading to the first experimental detection of gravitational radiation - a prediction of general relativity made by Einstein as early as 1916. In principle, a rotating dumb bell in the laboratory would lose energy by this mechanism, ...

  15. "You see how good-looking Lee Ann is!"

    DEFF Research Database (Denmark)

    Spanger, Marlene

    2012-01-01

    a poststructuralist feminist perspective, arguing that looks and bodily practices, based on different constellations of gender and sexuality and race and nationality, are important for the research situation. Bringing in two different examples, the article analyses the field relations, and the implied power relations......By investigating the case of female Thai migrants selling sexual services in Denmark, I argue that ‘the victim’ versus ‘the empowered subject’ is an undesirable binary for analysing how female migrants perform gendered subject positions in their everyday life. The article suggests......, - between the researcher(s) and the studied subjects that are constituted through gender, sexuality, race and nationality. These relations form the premises for producing material....

  16. Editorial: A message of thanks | Lee | Ostrich: Journal of African ...

    African Journals Online (AJOL)

    Ostrich: Journal of African Ornithology. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 87, No 3 (2016) >. Log in or Register to get access to full text downloads.

  17. Harry Lee Parker and paroxysmal dysarthria and ataxia.

    Science.gov (United States)

    Klaas, James P; Burkholder, David B; Singer, Wolfgang; Boes, Christopher J

    2013-01-15

    To review descriptions of paroxysmal dysarthria and ataxia in multiple sclerosis (MS), with special attention given to Parker and his 1946 case series. Evaluation of original publications describing paroxysmal dysarthria and ataxia, bibliographic information, writings, and unpublished letters from the Mayo Clinic Historical Unit. In 1940, Störring described a patient with MS with paroxysmal symptoms that included dizziness and trouble speaking, but also unilateral extremity weakness. In 1946, Parker published a series of 11 patients with paroxysmal dysarthria and ataxia. Six of these patients had MS, and he recognized this phenomenon as a manifestation of the disease. The term "paroxysmal dysarthria and ataxia" was first used in 1959 by Andermann and colleagues. Since that time, paroxysmal dysarthria and ataxia has become a well-recognized phenomenon in MS. More recent reports have suggested that the responsible lesion is located in the midbrain, near or involving the red nucleus. Parker was the first to accurately describe paroxysmal dysarthria and ataxia in patients with MS.

  18. "Sê sjibbolet": 'n intertekstuele lees | van Wyk | Tydskrif vir letterkunde

    African Journals Online (AJOL)

    Sê sjibbolet: an intertextual reading. This article pursues an intertextual reading of Adam Small's collection of poetry Sê sjibbolet (“Say shibboleth”). The collection is read alongside texts that refer to “shibboleth” in their titles i.e. works by Paul Celan, Jacques Derrida and Doris Salcedo. The analysis draws on the readings ...

  19. Diamond Jubi lee of the Academy Mid-Year Meeting

    Indian Academy of Sciences (India)

    1994-07-01

    Jul 1, 1994 ... and was the recipient of the 1977 Award of tt.e. Federation of Indian Chambers of Commerce arid. Industry. He was a Visiting Professor at the Indian. Institute of Science, Bangalore for 3 years after his retirement from MIDHANI in 1979, and. Technical Director of Kamani Metals and Alloys. Ltd. for a year in ...

  20. An Homage to the Bleak and Dismal World

    Directory of Open Access Journals (Sweden)

    Kim Yerim

    2016-12-01

    Full Text Available Han Kee Hyung and Lee Hye-Ryoung, eds. Chŏsuha ŭi sigan: Yŏm Sang-sŏp ŭl ikta 저수하의 시간, 염상섭을 읽다 [Time under the heaven tree: Reading Yŏm Sang-sŏp]. Seoul: Somyŏng ch’ulp’an, 2014. ISBN: 9788956265896. Heaven Tree offers justifiable and zealous attempts to commemorate Yŏm Sang-sŏp as a remarkable subject, one who was most acutely aware of the politics, society, and aesthetics of the period in which he lived. In addition, the twenty scrupulously researched and enlightening articles included in the collection unfold this attempt in a brilliant fashion, harking back to two earlier studies by Lee Bo-young and Kim Yun-sik. Those earlier books are the productive “ancestors” of Heaven Tree, in that the depth and magnitude of their reconstruction and reevaluation of Yŏm’s thoughts are analogous to what is achieved in this new collection. Nonetheless, as much as Heaven Tree is similar to its ancestors in terms of the passion and meticulousness demonstrated by the contributing authors, it proves to be a courageous offspring, as the authors further absorb, complement, and renew the existing research...

  1. Comorbidities in obstructive lung disease in Korea: data from the fourth and fifth Korean National Health and Nutrition Examination Survey

    Directory of Open Access Journals (Sweden)

    Park HJ

    2015-08-01

    Full Text Available Hee Jin Park, Ah Young Leem, Sang Hoon Lee, Ju Han Song, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Kyung Soo Chung Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Institute of Chest Disease, Yonsei University College of Medicine, Seoul, South Korea Background: Comorbidities can occur frequently in patients with chronic obstructive pulmonary disease (COPD and can influence mortality and morbidity independently. It is increasingly recognized that many patients with COPD have comorbidities that have a major impact on their quality of life and survival. Therefore, we investigated the prevalence of comorbidities in Korean COPD populations. Methods: We used data obtained in the 6 years of the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV and V. Among 50,405 subjects, 16,151 subjects aged ≥40 years who performed spirometry adequately were included in this study. Airway obstruction was defined as forced expiratory volume in 1 second/forced vital capacity <0.7, and the Global Initiative For Chronic Obstructive Lung Disease stage was used to evaluate the severity of airway obstruction. Statistical analyses were performed using SAS 9.2. Results: Among the 16,151 subjects (43.2% male, 56.8% female; mean age: 57.1 years for men and 57.2 years for women, 13.1% had obstructive lung function; 11.3%, restrictive lung function; and 75.6%, normal lung function. Among individuals with obstructive lung function, 45.3%, 49.4%, and 5.3% had mild, moderate, and severe and very severe airflow limitation. The prevalence of hypertension, diabetes mellitus (DM, underweight, and hypertriglyceridemia was higher in the obstructive lung function group than in the normal lung function group (49.6% vs 35.2%; 16.8% vs 10.5%; 3.3% vs 1.3%; 19.7% vs 17.0%. According to the severity of airway obstruction, hypertension and underweight were more common as severity increased

  2. Enesekaitsesituatsioonides vahetu sunni kasutamine vanglas. Karistusõiguslik ja haldusõiguslik analüüs / Anneli Soo, Kaidi Tarros

    Index Scriptorium Estoniae

    Soo, Anneli, 1984-

    2015-01-01

    Vanglaametniku poolt vahetu sunni kasutamisest enese või teise isiku kaitseks. Vahetu sunni kasutamise nõuetest vangistusõiguses, vanglaamentiku vastutuse välistamise tingimustest karistusseadustiku (KarS) alusel ning distsiplinaarvastutusest ja riigivastutusest. Asjakohasest kohtupraktikast

  3. Tahtluse vormid ning nende eristamine teoorias ja praktikas : [bakalaureusetöö] / Mattias Jõgi ; Tartu Ülikool, õigusteaduskond ; juhendaja: Anneli Soo

    Index Scriptorium Estoniae

    Jõgi, Mattias

    2010-01-01

    Tahtlusest Ameerika Ühendriikides ja mandri-Euroopas, tahtluse vormidest Eestis 1935. a. kriminaalseadustiku ja 1961. a. kriminaalkoodeksi järgi, tahtluse vormide eristamisest ja esinemisest kehtivas karistusseadustikus, kelmusest ja selle erikoosseisudest, kohtuotsustes tahtluse vormide eristamisest

  4. “Op die aarde net soos in die hemel”: Matteus se eskatologie as die koninkryk van die hemel wat reeds begin kom het

    Directory of Open Access Journals (Sweden)

    Andries van Aarde

    2008-01-01

    Full Text Available “On earth as it is in heaven”: Matthew’s eschatology as the kingdom of heaven that has come In the article time as both “imagined” and “experienced” is explained against the background of the first-century Mediterranean conceptualisation of time. This reading scenario is seen as over against a modern Eurocentric ethnocentric interpretation of the concept "apocalyptic- eschatology”. The aim of the article is to argue that Matthew’s narration of the demolition of the temple in Jerusalem concurs with his belief that the first followers of Jesus experienced the vision of the coming of the Son of man and that both these experiences are presented in Matthew as though Jesus’ crucifixion and resurrection are incidents of the past. Matthew’s eschatology centres on the view that the final consummation of time has already begun. The article explores the ethical appeal which is communicated through such an eschatological reading scenario. This appeal is summarised by Jesus’ words “On earth as it is in heaven”. The article consists of a conversation about core issues in mainstream interpretations of what Matthew’s eschatology could be within the narrative’s plot as it contextualised in formative Christianity and formative Judaism. The view assumed in this article is that the “time” and the experiences of Matthew’s church and those of Jesus and his disciples are considered to be integrated within the history of Israel.

  5. Ekologiese waarnemings van 'n Bergskilpadpopulasie, Geochelone pardalis Bell, 1828, soos aangeteken in die Soetdoring-Natuurreser-vaat in die Oranje-Vrystaat

    Directory of Open Access Journals (Sweden)

    M. Rall

    1985-12-01

    Full Text Available Hierdie studie poog om vas te stel of die bergskilpad Geochelone pardalis Bell, 1828, habitatsvoorkeure asook territoriale neigings toon. Geen territorialiteit bestaan nie maar wel loopgebiede waarbinne die skilpad meeste van sy aktiwiteite bedryf. Bewegingspatrone van 'n aantal individuele skilpaaie word bespreek. This study ascertains whether the mountain tortoise Geochelone pardalis Bell, 1828, shows habitat preferences and territorial tendencies. No territorialism was found but most activities took place within a certain range. Movement patterns of a number of individual tortoises are described.

  6. Kuritegeliku ühenduse mõiste : ne bis in idem põhimõte. Riigikohtu kriminaalkolleegiumi otsus asjas 3-1-1-57-09 / Anneli Soo

    Index Scriptorium Estoniae

    Soo, Anneli, 1984-

    2010-01-01

    Riigikohtu otsusest asjas 3-1-1-57-09: N. Kohtovi kaitsja vandeadvokaat Tarmo Pilve kassatsioon Tartu Ringkonnakohtu 18. veebruari 2009. a kohtuotsuse peale kriminaalasi N. Kohtovi süüdistuses KarS § 256 lg 1, § 120 ja § 121 järgi

  7. Laste seksuaalne väärkohtlemine - selle ennetamise võimalikkusest : [bakalaureusetöö] / Janika Soo ; Õigusinstituut ; juhendaja: Airi Ross

    Index Scriptorium Estoniae

    Soo, Janika

    2002-01-01

    Laste seksuaalse väärkohtlemise olemus, liigid, soodustavad asjaolud, viitavad märgid ja nende äratundmine, laste õigusi kaitsvad organisatsioonid, kehtiv õiguslik regulatsioon, juhtumi analüüs

  8. Aspekte van die genetiese proses by Opperman soos afgelei uit ’n variantestudie van 'Gedagtes by ’n sarkofaag'

    Directory of Open Access Journals (Sweden)

    E. Meihuizen

    2003-08-01

    Full Text Available Aspects of the genetic process in the poetry of D.J. Opperman based on an analysis of different versions of the poem 'Gedagtes by ’n sarkofaag' (Thoughts on a sarcophagus A study of the genesis of a literary text reveals the systematic changes effected by the author during the creative process, and an understanding of these creative tendencies foregrounds structural principles of the final text. In studying a larger corpus of the author’s work, scrutiny of text development affords the means to gain insight into stylistic, semantic and thematic characteristics of the author’s oeuvre. This article focuses on the genesis of D.J. Opperman’s poem “Gedagtes by ’n sarkofaag” within the theoretical framework of Dutch edition theory as represented by Dorleijn (1984, Mathijsen (1997 and De Bruijn (2000 in particular. The different phases of development in the genesis of “Gedagtes by ’n sarkofaag” are identified and represented in a synoptic apparatus. In the analysis of the textual development particular attention is paid to the creation of a symbolic level.

  9. Introductory Statement by Won-Soo Kim [International Conference on Nuclear Security: Commitments and Actions, Vienna (Austria), 5-9 December 2016

    International Nuclear Information System (INIS)

    Kim, Won-Soo

    2017-01-01

    We need to treat WMD risks and threats holistically. Lessons learned in one area can be emulated in another. The IAEA has learned valuable lessons through its own emergency management work and partnership with other UN agencies, including through the UN Counter-Terrorism Implementation Task Force. These lessons could be beneficial in developing response mechanisms for biological incidents.

  10. Uudised : Kaheksas "Credo". RAM alustab hooaega. šoti naistrio Eestis. Kingitus operetisõpradele / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2001-01-01

    Tallinnas toimuvast VIII rahvusvahelisest õigeusu vaimuliku muusika festivalist "Credo". RAM esineb 23. ja 26. sept. kavaga "Päikese- ja kuuvarjutuse palvelaul". šoti trio esineb Tallinnas ja Tartus ning annab õpitoa Viljandis. 12. sept. esitleti Estonia talveaias K. Karaski CD-plaati "Bajadeer"

  11. Proses Individuasi Carl Gustav Jung Pada Tokoh Erika Kohut Dalam Novel Sang Guru Piano Karya Elfriede Jelinek

    OpenAIRE

    Vidiyanti, M. Oktavia

    2007-01-01

    A personality structure that appears in Erika is similar to one of an important part of Carl Gustav Jung psychology. Jung states that personality is a psiko that covers consciousness and unconsciousness. This psiko will develop to be a stable unity. If every system develops in every individual absolutely, so a health and integrated personality will be achieved. That process in Jung is known as a self­ individualized process. The aim of individualism is a self­achievement. Individual is not on...

  12. Luthers salmer i vækkelsesbevægelsernes sang- og salmebøger 1890-2000

    DEFF Research Database (Denmark)

    Balslev-Clausen, Peter

    2011-01-01

    Artiklen gør rede for brugen af Luthers salmer i danske vækkelsesbevægelsers og ungdomsorganisationers sangbøger 1890-2000......Artiklen gør rede for brugen af Luthers salmer i danske vækkelsesbevægelsers og ungdomsorganisationers sangbøger 1890-2000...

  13. Topographic Map of Quadrangle 3566, Sang-Charak (501) and Sayghan-O-Kamard (502) Quadrangles, Afghanistan

    Science.gov (United States)

    Bohannon, Robert G.

    2006-01-01

    This map was produced from several larger digital datasets. Topography was derived from Shuttle Radar Topography Mission (SRTM) 85-meter digital data. Gaps in the original dataset were filled with data digitized from contours on 1:200,000-scale Soviet General Staff Sheets (1978-1997). Contours were generated by cubic convolution averaged over four pixels using TNTmips surface-modeling capabilities. Minor artifacts resulting from the auto-contouring technique are present. Streams were auto-generated from the SRTM data in TNTmips as flow paths. Flow paths were limited in number by their Horton value on a quadrangle-by-quadrangle basis. Peak elevations were averaged over an area measuring 85 m by 85 m (represented by one pixel), and they are slightly lower than the highest corresponding point on the ground. Cultural data were extracted from files downloaded from the Afghanistan Information Management Service (AIMS) Web site (http://www.aims.org.af). The AIMS files were originally derived from maps produced by the Afghanistan Geodesy and Cartography Head Office (AGCHO). Because cultural features were not derived from the SRTM base, they do not match it precisely. Province boundaries are not exactly located. This map is part of a series that includes a geologic map, a topographic map, a Landsat natural-color-image map, and a Landsat false-color-image map for the USGS/AGS (Afghan Geological Survey) quadrangles covering Afghanistan. The maps for any given quadrangle have the same open-file number but a different letter suffix, namely, -A, -B, -C, and -D for the geologic, topographic, Landsat natural-color, and Landsat false-color maps, respectively. The open-file report (OFR) numbers for each quadrangle range in sequence from 1092 - 1123. The present map series is to be followed by a second series, in which the geology is reinterpreted on the basis of analysis of remote-sensing data, limited fieldwork, and library research. The second series is to be produced by the USGS in cooperation with the AGS and AGCHO.

  14. Jevgeni Onegin. Proloog : [luuletused] / Aleksandr Puškin ; tlk. Betti Alver, August Sang, Paul-Eerik Rummo

    Index Scriptorium Estoniae

    Puškin, Aleksandr

    2006-01-01

    Sisu: Jevgeni Onegin. Proloog ; Tshaadajevile ; Uuestisünd ; "Ju päeva viimne valgus suri..." ; "Ju õhtus aeglaselt kaob kerge pilveviir..." ; Muusa ; Kümnes käsk ; Vang ; "Kes, lained, peatas teie hoo..." ; "Kui lootusrikkalt siis jääks maha maine ring..." ; Deemon ; Eluvanker ; Merele ; Kuulsuse ihaldus ; A. P. Kernile ; Talveõhtu ; Pihtimus ; Hoidjale ; "Mind valdab õnn, kui selja taha jätta..." ; Talvine tee ; "Ööhämarus on juudionnis..." ; "All kaevandeis, kus lasub öö..." ; "Maailma laias, kurvas stepis toovad..." ; Arion ; Poeet ; "Kesk ülikuid poeedi hooleks..." ; 19. oktoobril 1827 ; Talisman ; Sõpradele ; "Veel puhuvad jahedad tuuled..." ; Eelaimus ; Lill ; Ended ; "On talv. Mis teha maal? Ma pärin teenrilt aru..." ; Talvehommik ; "Kui viibin pühakoja pingis..." ; "Mu nimest sinule mis jääb? ; Poeedile ; Eleegia ; Värsid, mis loodud unetul ööl ; Mustlased ; "Ei hinda kalliks ma bakhandi noore hoogu..." ; Kaja ; "Ei endist rõõmu tunne hing..." ; Kaunitar ; "Peas hoidku jumal mõistus mul..." ; Ööbik ; "...Käisin jällegi..." ; "Ausamba rajasin ma endal̀ eluaegu..." ; Jevgeni Onegin XLIX, L, LI : katkendid värssromaanist. Eluloolisi andmeid autori kohta lk. 517

  15. Uudised : Marko Martini konkursiedu Kanadas. "Con brio" lõppkontserdile 6 esinejat. Tublid noored trompetistid / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2000-01-01

    M. Martin pälvis II koha III Esther Honensi nim. pianistide konkursil Kanadas. Konkursi "Con brio" lõppvooru pääsejatest. N. ja J.Ots olid edukad I rahvusvahelisel noorte trompetistide konkursil Jekabpilsis Lätis

  16. Music Information Seeking Behaviour Poses Unique Challenges for the Design of Information Retrieval Systems. A Review of: Lee, J. H. (2010. Analysis of user needs and information features in natural language queries seeking music information. Journal of the American Society for information Science and Technology, 61, 1025-1045.

    Directory of Open Access Journals (Sweden)

    Cari Merkley

    2010-12-01

    encompassed 57 different features, a small number of features dominated, with seven features used in over 25% of the queries posted and 33 features appearing in less than 10%. The seven most common features were person name, title, date, genre, role, lyric, and place reference.Lee categorized most of the queries as “known-item searches,” even though at times users provided incorrect information and many were looking for information about the musical item but not the item itself (p. 1035. Other interesting features identified by the author were the presence of “dormant searches,” long standing questions a user had about a musical item, sometimes for years, which were reawakened by hearing the song again or other events (p. 1037. Multiple versions of musical works and the provision of information gleaned third hand by users were also identified as complicating factors in correctly meeting musical information needs.Conclusion – While certain types of questions dominated among music queries posted on the Google Answers service, there were a wide variety of music information needs expressed by users. In some cases, the features provided by the user as clues to answering the query were very personal, and related to the context. in which they encountered the work or the mood a particular work or artist evoked. Such circumstances are not currently or adequately covered by existing bibliographic record standards, which focus on qualities inherent in the music itself. The author suggests that user context should play a greater role in the testing and development of music information retrieval systems, although the instability and variability of this type of information is acknowledged. In some cases this context could apply to other works (film, television, etc. in which a musical work is featured. Another potential implication for music information retrieval system development is a need to re-evaluate the terminology employed in testing to ensure that it is the language most

  17. Time for a new language for asthma control: results from REALISE Asia

    OpenAIRE

    David-Wang, Aileen; Price,David B; Cho,Sang-Heon; Ho,James Chung-Man; Jeong,Jae-Won; Liam,Chong-Kin; Lin,Jiangtao; Muttalif,Abdul Razak; Diahn-Warng,Perng; Tan,Tze-Lee; Neira,Glenn; Yunus,Faisal

    2015-01-01

    David Price,1,2 Aileen David-Wang,3 Sang-Heon Cho,4 James Chung-Man Ho,5 Jae-Won Jeong,6 Chong-Kin Liam,7 Jiangtao Lin,8 Abdul Razak Muttalif,9 Diahn-Warng Perng,10,11 Tze-Lee Tan,12 Faisal Yunus,13 Glenn Neira14 On behalf of the REcognise Asthma and LInk to Symptoms and Experience (REALISE) Asia Working Group 1Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK; 2Research in Real Life, Singapore; 3University of the Philippines-Philippine General Hospital, Manila, Philippine...

  18. Neoleptonema yongpilii E.-Y. Lee & I.K. Lee, gen. et sp. nov. (Phaeophyceae), based on morphological characters and RuBisCO spacer sequences

    DEFF Research Database (Denmark)

    Lee, E.-Y.; Pedersen, Poul Møller; Lee, I.K.

    2002-01-01

    Elachistaceae, Neoleptonema yongpilii gen. et sp. nov., phylogenetic relationships, plurilocular sporangia, RuBisCO spacer sequences......Elachistaceae, Neoleptonema yongpilii gen. et sp. nov., phylogenetic relationships, plurilocular sporangia, RuBisCO spacer sequences...

  19. Bronchoscopic lung volume reduction by endobronchial valve in advanced emphysema: the first Asian report

    Directory of Open Access Journals (Sweden)

    Park TS

    2015-07-01

    Full Text Available Tai Sun Park,1 Yoonki Hong,2 Jae Seung Lee,1 Sang Young Oh,3 Sang Min Lee,3 Namkug Kim,3 Joon Beom Seo,3 Yeon-Mok Oh,1 Sang-Do Lee,1 Sei Won Lee1 1Department of Pulmonary and Critical Care Medicine and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 2Department of Internal Medicine, College of Medicine, Kangwon National University, Chuncheon, Korea; 3Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Purpose: Endobronchial valve (EBV therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed.Patients and methods: This prospective open-label single-arm clinical trial examined the clinical efficacy and the safety of EBV in 43 consecutive patients (mean age 68.4±7.5, forced expiratory volume in 1 second [FEV1] 24.5%±10.7% predicted, residual volume 208.7%±47.9% predicted with severe emphysema with complete fissure and no collateral ventilation in a tertiary referral hospital in Korea.Results: Compared to baseline, the patients exhibited significant improvements 6 months after EBV therapy in terms of FEV1 (from 0.68±0.26 L to 0.92±0.40 L; P<0.001, 6-minute walk distance (from 233.5±114.8 m to 299.6±87.5 m; P=0.012, modified Medical Research Council dyspnea scale (from 3.7±0.6 to 2.4±1.2; P<0.001, and St George’s Respiratory Questionnaire (from 65.59±13.07 to 53.76±11.40; P=0.028. Nine patients (20.9% had a tuberculosis scar, but these scars did not affect target lobe volume reduction or pneumothorax frequency. Thirteen patients had adverse events, ten (23.3% developed pneumothorax, which included one death due to tension pneumothorax.Conclusion: EBV therapy was as effective and safe in Korean

  20. Regulation of glucose control in people with type 2 diabetes: a review and consensus.

    Science.gov (United States)

    Woo, Jeong-Taek; Park, Kyung Soo; Byun, Dong-Won; Ko, Kyung Soo; Chung, Yoon-Sok; Kim, Doo Man; Park, Tae Sun; Cha, Bong Soo; Lee, In Kyu; Park, Joong Yeol; Son, Hyun Shik; Lee, Moon-Kyu; Kim, Kwang Won; Son, Ho Young

    2010-02-01

    A conference was convened by the Korean Diabetes Association and the Korean Endocrine Society on September 7, 2009 to discuss and organize the results of research on intensive glucose control for the prevention of cardiovascular disease in patients with type 2 diabetes. Professor Kyung Soo Park led the conference, and Professors Kwang Won Kim and Ho Young Son acted as chairmen. Professors Doo Man Kim, Tae Sun Park, and Bong Soo Cha reported on intensive glucose control and diabetic complications, including the UK Prospective Diabetes Study (UKPDS), Diabetes Control and Complication Trial (DCCT) research results, the recently published Action to Control Cardiovascular Risk in Diabetes (ACCORD), Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE), and Veterans Affairs Diabetes Trial (VADT) research, as well as meta-analyses. Professor Jeong-Taek Woo reported on the manuscript written by the committee for the Korean Diabetes Association which dealt with the treatment of diabetes mellitus. Professors Kyung Soo Ko, Joong Yeol Park, Hyun Shik Son, Moon-Kyu Lee, Dong-Won Byun, and Yoon-Sok Chung participated in the discussion and collected information for the manuscript from all of the participants. The aim of the debate was to determine how to establish target goals for intensive glucose control and how to individualize those goals. The participants concluded that there was no need to modify the recommendation of maintaining an HbA1c under 6.5%, the current blood glucose treatment goal that is recommended by the Korean Diabetes Association. In addition, individual target goals for glucose control were recommended depending on the situation of each patient. We report on the consensus statement from the meeting.

  1. Silica nanoparticle-based dual imaging colloidal hybrids: cancer cell imaging and biodistribution

    Directory of Open Access Journals (Sweden)

    Lee H

    2015-08-01

    Full Text Available Haisung Lee,1 Dongkyung Sung,2 Jinhoon Kim,3 Byung-Tae Kim,3 Tuntun Wang,4 Seong Soo A An,5 Soo-Won Seo,6 Dong Kee Yi4 1Molecular Diagnostics, In Vitro Diagnostics Unit, New Business Division, SK Telecom, 2Department of Life Sciences, Graduate School of Korea University, 3Interdisciplinary Graduate Program of Biomedical Engineering, School of Medicine, Sungkyunkwan University, Samsung Medical Center, 4Department of Chemistry, Myongji University, Seoul, 5Department of Bionanotechnology, Gachon Medical Research Institute, Gachon University, Seongnam, 6Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea Abstract: In this study, fluorescent dye-conjugated magnetic resonance (MR imaging agents were investigated in T mode. Gadolinium-conjugated silica nanoparticles were successfully synthesized for both MR imaging and fluorescence diagnostics. Polyamine and polycarboxyl functional groups were modified chemically on the surface of the silica nanoparticles for efficient conjugation of gadolinium ions. The derived gadolinium-conjugated silica nanoparticles were investigated by zeta potential analysis, transmission electron microscopy, inductively coupled plasma mass spectrometry, and energy dispersive x-ray spectroscopy. MR equipment was used to investigate their use as contrast-enhancing agents in T1 mode under a 9.4 T magnetic field. In addition, we tracked the distribution of the gadolinium-conjugated nanoparticles in both lung cancer cells and organs in mice. Keywords: dual bioimaging, MR imaging, silica colloid, T1 contrast imaging, nanohybrid

  2. Injury profile of non-contact sports for Perak SUKMA athletes | Lee ...

    African Journals Online (AJOL)

    The purpose of this study is to identify the injury profile of non-contact sports among Perak SUKMA athletes. The data from this injury is examined based on the five research questions which are nature of injury, body part, severity of injury (mild, moderate, severe), types of injury (acute or chronic), and factors of injury.

  3. Mabel Lee and Louise Pound: The University of Nebraska's Battle Over Women's Intercollegiate Athletics

    National Research Council Canada - National Science Library

    Kristi, Lowenthal

    1999-01-01

    Mirroring a cultural shift that brought the American middle class from the Victorian era into the modern era, women's intercollegiate sports encountered stiff resistance from the two overlapping social groups...

  4. St Joseph's Hospital, Bon Secours Care Village, Mount Desert, Lee Road, Cork.

    LENUS (Irish Health Repository)

    Farrell, Eric

    2011-01-31

    Abstract Background Bone grafts are required to repair large bone defects after tumour resection or large trauma. The availability of patients\\' own bone tissue that can be used for these procedures is limited. Thus far bone tissue engineering has not lead to an implant which could be used as alternative in bone replacement surgery. This is mainly due to problems of vascularisation of the implanted tissues leading to core necrosis and implant failure. Recently it was discovered that embryonic stem cells can form bone via the endochondral pathway, thereby turning in-vitro created cartilage into bone in-vivo. In this study we investigated the potential of human adult mesenchymal stem cells to form bone via the endochondral pathway. Methods MSCs were cultured for 28 days in chondrogenic, osteogenic or control medium prior to implantation. To further optimise this process we induced mineralisation in the chondrogenic constructs before implantation by changing to osteogenic medium during the last 7 days of culture. Results After 8 weeks of subcutaneous implantation in mice, bone and bone marrow formation was observed in 8 of 9 constructs cultured in chondrogenic medium. No bone was observed in any samples cultured in osteogenic medium. Switch to osteogenic medium for 7 days prevented formation of bone in-vivo. Addition of β-glycerophosphate to chondrogenic medium during the last 7 days in culture induced mineralisation of the matrix and still enabled formation of bone and marrow in both human and rat MSC cultures. To determine whether bone was formed by the host or by the implanted tissue we used an immunocompetent transgenic rat model. Thereby we found that osteoblasts in the bone were almost entirely of host origin but the osteocytes are of both host and donor origin. Conclusions The preliminary data presented in this manuscript demonstrates that chondrogenic priming of MSCs leads to bone formation in vivo using both human and rat cells. Furthermore, addition of β-glycerophosphate to the chondrogenic medium did not hamper this process. Using transgenic animals we also demonstrated that both host and donor cells played a role in bone formation. In conclusion these data indicate that in-vitro chondrogenic differentiation of human MSCs could lead to an alternative and superior approach for bone tissue engineering.

  5. The Consumer’s Opinions of the Food Service System: The 1973 Fort Lee Survey

    Science.gov (United States)

    1974-05-01

    Italian 0 08 Japanese 012 013 014 015 016 Polish (& Eastern Europe) Soul Southern Spanish (not Mexican) Other (please specifY------~ What...10 o 03 French o 11 0 04 General American Style 0 12 0 05 German 0 13 0 06 Greek 0 14 0 07 Italian 0 15 0 08 Japanese 0 16 Mexican New England...34Jzio"lc .!{!.* ~%*. 0% a. a. 6% 4% ’i’c: Less than ~% Table 5 Preferred Foods Cuisine General American Soul Southern English Italian

  6. Die opstel en evaluering van \\'n lees- en spelprogram vir Sesotho ...

    African Journals Online (AJOL)

    -speaking grade 1 learners, the value of a reading and spelling program for such learners is investigated. The research hypotheses postulates that the reading and spelling skills of Sesotho-speaking grade 1 learners that are exposed to a ...

  7. Lees' loss prevention in the process industries: hazard identification, assessment and control

    National Research Council Canada - National Science Library

    Mannan, Sam

    2012-01-01

    ... choose. As in the thronged and the lighted ways, so in the dark and the desert they stand, Wary and watchful all their days that their brethren's days may be long in the land.' Rudyard Kipling (The Sons of Martha, 1907) Wo einer kommt and saget an, Er hat es allen recht getan, So bitten wir diesen lieben Herrn, Er wo ¨ ll uns solche Kunste auch lehrn (...

  8. A critique of the Lees-Marshment market-oriented party model

    DEFF Research Database (Denmark)

    Ormrod, Robert P.

    2006-01-01

    between the related concepts of 'market orientation' and 'marketing orientation'. Empirical studies demonstrate problems with the model when applied to certain party types and electoral systems, the limitations on implementation of the model due to ideology and scarce resources, the partial application...

  9. 77 FR 60137 - Lee Metcalf National Wildlife Refuge, Ravalli County, MT; Final Comprehensive Conservation Plan...

    Science.gov (United States)

    2012-10-02

    ... management purpose, for migratory birds'' (Migratory Bird Conservation Act); and (2) ``for (a) incidental... migratory birds. Some wetland impoundments and U.S. Fish and Wildlife Service (nonpublic) roads would be removed or reduced in size to allow for river migration and to restore native gallery and riverfront...

  10. Operation Strong Wind (Fort Lee’s Response to a Local Tornado Disaster, 6 August 1993)

    Science.gov (United States)

    1993-11-01

    Interstate 95, and less than a mile from Old Towne and Pocahontas Island. Most destruction happened at Wal- Mart’s 110,000 square foot store which employed 400...area which was in the process of making a strong economic statement. Next to that area was an historic black community on Pocahontas Island in the... happen was Petersburg should have asked the governor that he request Federal troops. The governor in turn would have called the Federal Emergency

  11. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, Lee County, Alabama and Incorporated Areas

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  12. Global Marketing of Indigenous Culture: Discovering Native America with Lee Tiger and the Florida Miccosukee

    Science.gov (United States)

    Wiedman, Dennis

    2010-01-01

    Indigenous scholars such as Seminole/Shawnee historian, Donald Fixico, drew attention to the lack of academic literature about the proactive, planned, and strategic actions of indigenous peoples. Most histories portray indigenous peoples as responding, accommodating, and assimilating to non-Indians and the US government. This article highlights…

  13. Lee and Rhee et al., Afr J Tradit Complement Altern Med. (2016) 13 ...

    African Journals Online (AJOL)

    A preliminary or control paw withdrawal threshold was measured for each rat before drug injection. The cut-off value was determined as 30s in order to avoid tissue damage (Hargreaves et al., 1988). Chemical Test. The rats were housed in transparent plastic boxes with a floor made of 6mm wire mesh. After a 5-10min ...

  14. Meat Entree Item Production Guides Developed for Use in Ft. Lee Interim Central Food Preparation Facility

    Science.gov (United States)

    1975-03-01

    454 Col-Flo-67 Starch 0.70 Stock or water, cold 32.96 Pepper, black 0.01 Caramel coloring 0.01 Soup A gravy base, 0*56 beef 0.50 23.50...Type I, Class 1, 2 or 3 8. Flour, wheat, pastry - 7287-165-6898 FED-N-F-481, Type 1, Class B, Style 2 9. Food coloring, caramel - 8950-12940-782-2181...starch Stock or cold water Pepper, black Caramel coloring Soup ft gravy base, beef flavored 1.75 0.50 227 87.65 25.00 11350 0.04 0.01 5 O.O’l

  15. Aerial Photography and Imagery, Ortho-Corrected - 2007 Digital Orthophotos - FDEM - Lee County

    Data.gov (United States)

    NSGIC Education | GIS Inventory — This data set is one component of the Florida Division of Emergency Management's (FDEM) Project Management and Technical Services for Mapping within Coastal Florida...

  16. "Communication English" aan tegniese kolleges : 'n evaluering in die lig van lees- en spelvaardighede

    OpenAIRE

    2015-01-01

    M.Ed. The purpose of this study is primarily to evaluate the curriculum of the subject Communication English with specific reference to the component of reading and spelling. The rationale is to determine whether or not the reading and spelling skills of college students comply with the requirements of the private sector and, if found to be inadequate, appropriate recommendations would be made. The detrimental effect of reading and spelling problems on a person's entire being and self-actu...

  17. Lee and Park., Afr J Tradit Complement Altern Med. (2016) 13(2):72 ...

    African Journals Online (AJOL)

    Inflammation, the process aimed at restoring homeostasis after an insult, can be more damaging than the insult itself if uncontrolled, excessive, or prolonged ... Cells of the innate immune system detect pathogen-associated molecular patterns or endogenous molecules released as a result of tissue injury or inflammation ...

  18. Järvalaste Seltsi taassünd / Ants Kraut, Elle Lees

    Index Scriptorium Estoniae

    Kraut, Ants, 1955-

    2011-01-01

    7. juunil 2010 tähistati järvalaste ühendamise eestvõitleja Vaike Kotkase 90 juubelit. 4. detsembril 2010 toimus pidulik üldkoosolek, kus Tallinna Järvalaste Muinsuskaitse Selts otsustas jätkata ajaloolise nime Tallinna Järvalaste Selts all, tegutsedes Eesti Muinsuskaitse Seltsi allüksusena

  19. 77 FR 18852 - Lee Metcalf National Wildlife Refuge, Stevensville, MT; Draft Comprehensive Conservation Plan and...

    Science.gov (United States)

    2012-03-28

    ... visitors a consistent message about the purposes and values of the refuge and the mission of the Refuge... technicians (one full time and one career seasonal), and a visitor services specialist who would serve as a... Availability of Comments Before including your address, phone number, email address, or other personal...

  20. Spike Lee, Short Films and Social Issues in the English Classroom.

    Science.gov (United States)

    Kelly, Ernece B.

    In the past few years many movies have addressed social issues such as AIDS, parental estrangement, aging, battered women and children, and racism. Teachers of teenagers can capitalize on these kinds of serious films in two ways: by assuming that students have thought about some serious issues and by building on that assumption. Three movies of…

  1. Only three personality factors are fully replicable across languages: Reply to Ashton and Lee

    Czech Academy of Sciences Publication Activity Database

    De Raad, B.; Barelds, D.P.H.; Mlacić, B.; Church, A.T.; Katigbak, M. S.; Ostendorf, F.; Hřebíčková, Martina; Di Bias, L.; Szirmak, S.

    2010-01-01

    Roč. 44, č. 4 (2010), s. 442-445 ISSN 0092-6566 R&D Projects: GA ČR GAP407/10/2394 Institutional research plan: CEZ:AV0Z70250504 Keywords : lexical approach * factor replicability * cross-cultural * three factor s Subject RIV: AN - Psychology Impact factor : 1.756, year: 2010

  2. Fungal and enzymatic remediation of a wine lees and five wine-related distillery wastewaters

    CSIR Research Space (South Africa)

    Strong, PJ

    2008-09-01

    Full Text Available independently to determine its role in phenolic compounds degradation and colour change. The fungal treatment resulted in decreases in the wastewater chemical oxygen demand of up to 83 ± 2.1%, phenolic compounds of 87 ± 1.6% and colour of 88 ± 4.7%. Although...

  3. Arhitektuuriline vahendamine: kliima vs kultuur = Architectural mediations: climate vs culture / Franklin Lee, Anne Save de Beaurecueil

    Index Scriptorium Estoniae

    Lee, Franklin

    2011-01-01

    Tegelemisest Architectural Associationi 2. diplomistuudios ja büroos SUBdV keskkondlike ja kultuuriliste mõjurite duaalsusega arhitektuuris. Teemat on uuritud kolmes valdkonnas: sile vs artikuleeritud, keskkond vs ornament, kõrgtehnoloogia vs madaltehnoloogia. Architectural Association'i ja Hollandi Arhitektuuriinstituudi töötoast São Paulos 2010. a. suvel

  4. Een teks – meerdere betekenisse: Hoe lees ons die Bybel? | van ...

    African Journals Online (AJOL)

    One text – multiple meanings: How do we read the. Bible? This article discusses three ways of reading the Bible that are evident in the current theological debate in South Africa: a fundamentalist, foundationalist and critical reading. A brief description and evaluation of the three reading strategies are given. It is indicated that ...

  5. Tanith Lee's "Wolfland" and Suzy McKee Charnas's "Boobs" - Modern Tales of Magic

    OpenAIRE

    VILJANEN, EEVA

    2005-01-01

    Hakutermit: feministinen satu, Punahilkka, ihmissusi, fantasia, gotiikka, groteski Tämän pro gradu ­tutkielman tavoitteena on tarkastella kahta novellia, Tanith Leen ”Wolfland” ja Suzy McKee Charnasin ”Boobs”(Leena Peltosen suomennos ”Tissit” 1990) feministisen sadunkirjoitusperinteen näkökulmasta. Pyrin analysoimaan kirjailijoiden tapaa käyttää fantasian, gotiikan ja groteskin kuvastoa merkityksiä luodessaan. ”Wolfland” perustuu Perault’n ja Grimmin veljesten klassiseen satuun P...

  6. n resepsieteoretiese benadering tot die lees van Romeine 7:7—25

    African Journals Online (AJOL)

    between Augustine and Pelagius, leading up to the differences between exegetes and sistematic theologians in our ...... leerlinge is gevra om in volgorde elke teken (dit wil sê elke letter en punktuasieteken) in die eerste ses tot ... Pelagius verset het en in watter intense stryd hulle gewikkel was (vgl. Schulze 1978: 13—141).

  7. Mira y lee: Libro de actividades, 1 (Look and Read: Workbook 1).

    Science.gov (United States)

    Martinez, Emiliano; And Others

    This workbook, designed to be used with the textbook of the same title (FL 004 271), contains exercises, riddles, puzzles, coloring activities, and reinforcement of various word-perception skills and sentences. Included is a step-by-step procedure of phonetic analysis. The intention of the workbook is to enable students to increase their ability…

  8. Mira y lee: Libro de lectura 1, nivel 1 (Look and Read: Reader 1, Level 1).

    Science.gov (United States)

    Martinez, Emiliano; And Others

    This reading textbook contains a series of stories designed to relate to the natural interest of the school child. Students learn about a Puerto Rican family living in New York. New vocabulary is introduced gradually for the student to memorize. Included are exercises in oral expression and comprehension, auditory discrimination, intonation,…

  9. Lee y trabaja: Libro de lectura 2, nivel 1 (Read and Work: Reader 2, Level 1).

    Science.gov (United States)

    Martinez, Emiliano; and Others

    This reading textbook, the second of a series, is an anthology of stories designed to relate to the natural interest of the elementary school child. On this level the number of words to memorize is increased (on the average, four per unit) while at the same time, the study of word variants is introduced to begin analysis exercises based on the…

  10. Lee y trabaja: Libro de actividades, 2 (Read and Work: Workbook 2).

    Science.gov (United States)

    Martinez, Emiliano; And Others

    This workbook, designed to be used with the textbook of the same title (FL 004 272), contains exercises, riddles, puzzles, coloring activities, and reinforcement of various word-perception skills and sentences. Included is a step-by-step procedure of phonetic analysis. The intention of the workbook is to enable students to increase their ability…

  11. 75 FR 28643 - Pine Island, Matlacha Pass, Island Bay, and Caloosahatchee National Wildlife Refuges, Lee and...

    Science.gov (United States)

    2010-05-21

    ..., including fishing, canoeing, kayaking, motor boating, parasailing, windsurfing, ski tubing, using personal... wildlife and habitat values and would pursue completion of the approved acquisition boundaries from willing... and importance of these refuges in the landscape, and the importance of minimizing the impacts of...

  12. Alleviation of UV-B stress in Arabidopsis using tea catechins | Lee ...

    African Journals Online (AJOL)

    Ultraviolet-B (UV-B) has been confirmed to be harmful to living organisms and it is of concern that the amount of UV-B radiation reaching the earth's surface is increasing because of the depletion of the stratospheric ozone layer. Effect of different levels of tea catechins on morphological damage and expression of chalcone ...

  13. 75 FR 27576 - J.N. “Ding” Darling National Wildlife Refuge, Lee County, FL

    Science.gov (United States)

    2010-05-17

    ... threats to rare, threatened, and endangered species; (7) insufficient baseline wildlife and habitat data and lack of a comprehensive habitat management plan; and (8) insufficient resources to address refuge... changes. We would evaluate the need for and ability to provide parking at the Shell Mound Trail to address...

  14. Audrey Tautouga Coco jälgedes / Audrey Tautou ; intervjueerinud Lee Hanael

    Index Scriptorium Estoniae

    Tautou, Audrey, 1976-

    2009-01-01

    Näitlejanna mängib peaosa äsja esilinastunud eluloofilmis "Coco enne Chaneli" ("Coco avant Chanel", režissöör Anne Fontaine, Prantsusmaa 2009) ja on Chaneli moemaja parfüümi Chanel №5 reklaaminägu

  15. 76 FR 16636 - Pine Island, Matlacha Pass, Island Bay, and Caloosahatchee NWRs, Lee County, FL; Final...

    Science.gov (United States)

    2011-03-24

    ...)) requirements. We completed a thorough analysis of impacts on the human environment, which we included in the... toward the mission of the National Wildlife Refuge System, consistent with sound principles of fish and... will coordinate with the partners to address concerns related to the impacts from water quality...

  16. Aerial Photography and Imagery, Ortho-Corrected - 2010 NAIP Imagery - Lee County

    Data.gov (United States)

    NSGIC Education | GIS Inventory — This data set contains polygons delineating the seams boundary between acquired imagery used in the creation of DOQQs and compressed county mosaic (CCM). The DOQQ...

  17. Aerial Photography and Imagery, Ortho-Corrected - 2011 Digital Orthophotos - Lee County

    Data.gov (United States)

    NSGIC Education | GIS Inventory — The dataset consists of tiled orthogonal imagery produced from nadir images captured by Pictometry International January 2nd and March 21st, 2011. Automatic aerial...

  18. Lee and Park., Afr J Tradit Complement Altern Med. (2016) 13(2):72 ...

    African Journals Online (AJOL)

    binding with the complex CD14, myeloid differentiation protein 2, and Toll-like receptor 4 (Paciello et al., 2013). .... colony-stimulating factor (GM-CSF), leukemia inhibitory factor (LIF; IL-6 class cytokine), lipopolysaccharide-induced CXC ...... The actual effect of CCH in acute and chronic inflammatory diseases deserves.

  19. Shelf currents, lee-trapped and transient eddies on the inshore ...

    African Journals Online (AJOL)

    An ADCP mooring at a depth of 32 m off Port Alfred indicated that the countercurrent typically lasted a few days, but at times remained in the same direction for as long as 10 days. Velocities ranged between 20 and 60 cm s–1 with maximum values of ~80 cm s–1. The S–ADCP data also highlighted the existence of cyclonic ...

  20. Tsüklist "Spoon Riveri koolnud" : [luuletused] / Edgar Lee Masters ; tõlk. Boris Kabur

    Index Scriptorium Estoniae

    Masters, Edgar Lee

    2008-01-01

    Sisu: Poeet Theodore ; Lucinda Matlock ; Willard Fluke ; Diakon Taylor ; Viiuldaja Jones ; Dora Williams ; John M. Church ; Vene Sonja ; Petit, poeet ; Pastor Abner Peet ; Yee Bow ; Roger Heston ; Carl Hamblin ; Hortense Robbins ; Tom Merritt ; Proua Merritt ; Elmer Karr ; Anne Rutledge ; Marie Bateson ; Scholfield Huxley ; Willie Metcalf. Elu- ja loomeloolisi andmeid autori kohta lk. 519-520

  1. Only three personality factors are fully replicable across languages: Reply to Ashton and Lee

    Czech Academy of Sciences Publication Activity Database

    De Raad, B.; Barelds, D.P.H.; Mlacić, B.; Church, A.T.; Katigbak, M. S.; Ostendorf, F.; Hřebíčková, Martina; Di Bias, L.; Szirmak, S.

    2010-01-01

    Roč. 44, č. 4 (2010), s. 442-445 ISSN 0092-6566 R&D Projects: GA ČR GAP407/10/2394 Institutional research plan: CEZ:AV0Z70250504 Keywords : lexical approach * factor replicability * cross - cultural * three factors Subject RIV: AN - Psychology Impact factor: 1.756, year: 2010

  2. Edwards: kommunismi ajalugu on vaja tunda, et see ei korduks / Lee Edwards

    Index Scriptorium Estoniae

    Edwards, Lee

    2011-01-01

    Intervjuu Washingtonis asuva kommunismiohvrite mälestusmärgi rajamise fondi esimehe USA konservatiivse mõttekoja Heritage Foundation liikmega kommunismi olemusest ja ajaloost ning selle selgitamise vajadusest

  3. Järvamaa : Äripäev maakonnas / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2007-01-01

    Järvamaa ettevõtete TOP. Vt. samas: Mäo tehnoküla paneb Eestimaa südame tuksuma. Diagramm; Järva gasellid üle Eesti ilma ei tee; Käsitöö annab Vikingile konkurentsieelise; Paide MEK toodab metallkonstruktsioone; Ülemaailmne turg tagab kasvuvõimaluse; Mäo tehnopargil piire pole. Küsimustele vastab Toomas Agasild

  4. Bruce Lee vs. Fu Manchu: Kung Fu Films and Asian American Stereotypes in America.

    Science.gov (United States)

    Farquhar, Judith; Doi, Mary L.

    1978-01-01

    Discussed in this article are numerous films which feature Asian characters and the influence these films have on stereotyped images of Asians and prevailing racist attitudes toward Asian Americans. (EB)

  5. Evaluation of Learning Strategies Training Program 94B10 Fort Lee, Virginia.

    Science.gov (United States)

    1981-11-30

    28 perform during evaluation; and 3) differences between Cycle 1 and Cycle 2 experimental group student performance casts doubt on whether superiority...Creamy, cheesy, macaroni flavor (not bland, dry, or sticky) - Season to taste (not flat or overpowering) - Sauce castes smooth (not lumpy or floury...takte* * . ** .....1/4 x rawA (13 o ladle ) egg 4.1 :..Id talIp4j9fr4$tu gUluut On je ~ ouem I 4qol4ea brown. ~Q I$T 5 M peeusay, gently g99~I94 u ith wit

  6. The Anatomy of the Solemn in Ezenduka's “Lee Nnukwu Ukochukwu”

    African Journals Online (AJOL)

    Among Igbo liturgical music composers of the last fifty years, Ezenduka has stood tall like a mountain peak in a range of many mountains. The popularity of his compositions has provoked unusual interest among sacred musicologists and ethnomusicologists. The search for the basic and unique elements of his ...

  7. Brassia campestris L. ssp. chinensis L.var. utilis Tsen et Lee

    African Journals Online (AJOL)

    omodibo

    2012-12-31

    Dec 31, 2012 ... Soft Rot Disease Caused by Pectobacterium carotovorum subsp. carotovorum of Chinese Cabbage Followed by Climate Change in. Highlands of Korea. Society for plant pathology in China Annual. Academic Symposium, Chinese agricultural science and Technology. Press, Yichang, Hubei, China.

  8. Impact of Parameterized Lee Wave Drag on the Energy Budget of an Eddying Global Ocean Model

    Science.gov (United States)

    2013-08-26

    of Mexico and other regions in Fig. 2b of Arbic et al. (2010) relative to their Fig. 2a. In subsequent versions of HY- COM simulations with embedded...use of the leap- frog time-stepping scheme (Griffies et al., 2000), it is an unmeasured source of dissi- pation. An associated imbalance in surface...Molines, J.-M., New , A.L., 2001. Circulation characteristics in three eddy- permitting models of the North Atlantic. Progr. Oceanogr. 48, 123–161

  9. An approach to epilepsy | Lee-Pan | South African Medical Journal

    African Journals Online (AJOL)

    It assists in determining the aetiology and has a material impact on the choice of management. Appropriate management of seizures starts with identifying the various seizure types. Time will tell whether or not this new descriptive approach to organisation of seizures makes the task easier and more effective.

  10. Mediaoverdracht in het ouderlijk gezin: De gevolgen van ouderlijke mediasocialisatie voor huidige lees- en televisievoorkeuren

    NARCIS (Netherlands)

    Notten, N.J.W.R.; Kraaykamp, G.L.M.; Konig, R.P.

    2011-01-01

    This study analyses the intergenerational transmission of book reading and television viewing preferences. Central are the long-term effects of the parental media example and parental media guidance activities during one's childhood on adult highbrow and lowbrow media preferences. We used

  11. Mediaoverdracht in het ouderlijk gezin: de gevolgen van ouderlijke mediasocialisatie voor huidige lees- en televisievoorkeuren

    NARCIS (Netherlands)

    Notten, N.; Kraaykamp, G.; Konig, R.

    2011-01-01

    This study analyses the intergenerational transmission of book reading and television viewing preferences. Central are the long-term effects of the parental media example and parental media guidance activities during one’s childhood on adult highbrow and lowbrow media preferences. We used

  12. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, LEE COUNTY, MISSISSIPPI AND INCORPORATED AREAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  13. Using the Light Microscopy Module (LMM) on the International Space Station (ISS), The Advanced Colloids Experiment (ACE) and MacroMolecular Biophysics (MMB)

    Science.gov (United States)

    Meyer, William; Foster, William M.; Motil, Brian J.; Sicker, Ronald; Abbott-Hearn, Amber; Chao, David; Chiaramonte, Fran; Atherton, Arthur; Beltram, Alexander; Bodzioney, Christopher M.; hide

    2016-01-01

    The Light Microscopy Module (LMM) was launched to the International Space Station (ISS) in 2009 and began science operations in 2010. It continues to support Physical and Biological scientific research on ISS. During 2016, if all goes as planned, three experiments will be completed: [1] Advanced Colloids Experiments with Heated base-2 (ACE-H2) and [2] Advanced Colloids Experiments with Temperature control (ACE-T1). Preliminary results, along with an overview of present and future LMM capabilities will be presented; this includes details on the planned data imaging processing and storage system, along with the confocal upgrade to the core microscope. [1] a consortium of universities from the State of Kentucky working through the Experimental Program to Stimulate Competitive Research (EPSCoR): Stuart Williams, Gerold Willing, Hemali Rathnayake, et al. and [2] from Chungnam National University, Daejeon, S. Korea: Chang-Soo Lee, et al.

  14. Light Microscopy Module: International Space Station Premier Automated Microscope

    Science.gov (United States)

    Sicker, Ronald J.; Foster, William M.; Motil, Brian J.; Meyer, William V.; Chiaramonte, Francis P.; Abbott-Hearn, Amber; Atherton, Arthur; Beltram, Alexander; Bodzioney, Christopher; Brinkman, John; hide

    2016-01-01

    The Light Microscopy Module (LMM) was launched to the International Space Station (ISS) in 2009 and began hardware operations in 2010. It continues to support Physical and Biological scientific research on ISS. During 2016, if all goes as planned, three experiments will be completed: [1] Advanced Colloids Experiments with Heated base-2 (ACE-H2) and [2] Advanced Colloids Experiments with Temperature control (ACE-T1). Preliminary results, along with an overview of present and future LMM capabilities will be presented; this includes details on the planned data imaging processing and storage system, along with the confocal upgrade to the core microscope. [1] a consortium of universities from the State of Kentucky working through the Experimental Program to Stimulate Competitive Research (EPSCoR): Stuart Williams, Gerold Willing, Hemali Rathnayake, et al. and [2] from Chungnam National University, Daejeon, S. Korea: Chang-Soo Lee, et al.

  15. Proteinograma do líquido cefalorraquidiano e do sôro sangüíneo na mielose funicular

    Directory of Open Access Journals (Sweden)

    A. Spina-França

    1962-09-01

    Full Text Available O presente estudo compreende a análise do proteinograma do LCR de 14 pacientes portadores de mielose funicular; em 12 foi feito também o estudo do proteinograma do sôro. Os resultados foram analisados e relacionados a outros aspectos dos casos estudados, como o tempo de duração da doença, a intensidade da sintomatologia neurológica, as alterações hematológicas e a capacidade de absorção da radiocianocobalamina. O proteinograma do LCR era do tipo liquórico propriamente dito, apresentando como particularidade o aumento do teor de β-globulina, o qual é descrito como representativo das afecções de tipo degenerativo do SNC. No soro a principal modificação verificada foi a presença da fração intermediária entre as globulinas β e γ, fato anteriormente assinalado por Furtado. A análise estatística permitiu verificar que havia estreita correlação entre o teor de β-globulina no LCR e a intensidade do quadro neurológico. O teor liquórico de β-globulina parece estar vinculado ao predomínio da lesão central sôbre a periférica, predomínio que se correlaciona ao déficit de absorção de vitamina B12. O teor de β-globulina no LCR mostrou-se também proporcional à deficiência de fator intrínseco no suco gástrico. Por outro lado, a elevação do teor dessa fração proteica no LCR mostrou-se inversamente proporcional à absorção intestinal de vitamina B12. O aumento de β-globulina no LCR parece, por isso, refletir mais de perto o acometimento do sistema nervoso central na verdadeira moléstia de AddisonBiermer. Nos casos em que não havia déficit do fator intrínseco o teor dessa globulina no LCR motrava-se mais próximo da normalidade.

  16. Níveis de Energia na Dieta para Bubalinos em Crescimento Alimentados em Confinamento: 1. Desempenho e Bioquímica de Nutrientes Sangüíneos

    Directory of Open Access Journals (Sweden)

    Franzolin Raul

    2001-01-01

    Full Text Available Vinte e sete bubalinos em crescimento da raça Mediterrâneo foram mantidos em confinamento por cerca de 140 dias, visando avaliar os efeitos de diferentes níveis de energia ingerida sobre o desempenho e as concentrações de glicose, proteína total e uréia no sangue. Os tratamentos constituíram de três níveis de ingestão de energia: BE (Baixa Energia, RE (Requerida Energia e AE (Alta Energia. RE foi calculado com 125 kcal/kg0,75/dia de energia metabolizável para mantença; BE com 20% abaixo e AE com 20% acima desse nível, adotando-se ganho diário médio de 800 g, correspondendo a 10 kcal de EM/g de ganho para animais até 250 kg e mais 0,02 kcal/kg de peso acima de 250 kg/g de ganho. Amostras de sangue foram colhidas em três períodos, ou seja, 44, 66 e 88 dias após o início do experimento. Houve diferenças significativas no ganho de peso médio diário entre BE (773,9 g, RE (942,8 g e AE (1071,8 g e nos níveis de uréia no soro. As ingestões médias de matéria seca (g/kg0,75 e de energia metabolizável estimadas (Mcal/animal/dia foram, respectivamente: 89,54 e 17,13 para BE, 92,87 e 18,24 para RE e 95,66 e 20,94 para AE. Com base no ganho de peso obtido e na quantidade diária de energia metabolizável ingerida, concluiu-se que o requerimento de energia metabolizável total para bubalinos em crescimentos recomendado por KEARL (1982 encontra-se superestimado em média de 14,73%.

  17. Õnnistus : [luuletused] / Charles Baudelaire ; tlk. Johannes Semper, Ants Oras, August Sang, Ilmar Laaban, Ain Kaalep, Indrek Hirv, Jaan Kross

    Index Scriptorium Estoniae

    Baudelaire, Charles, 1821-1867

    2006-01-01

    Sisu: Õnnistus ; Albatross ; Ülenemine ; Vastavusi ; Kutse teekonnale ; Muusika ; Elav tungal ; Vaenlane ; Ebaõnn ; Mees ja meri ; Ilu ; Hiigelnaine ; Hümn ilule ; Kalliskivid ; Eksootiline lõhn ; Raibe ; Vampiir ; Pihtimus ; Kass ; Mis ütled, vaene hing ; Lõhnapudel ; Sume laotus ; Kutse teele ; Sügissonett ; Öökullid ; Olematuse maitse ; Spliin : "Mu mälestuste last on nii painajalik..." ; Spliin : "Ma olen nii kui vürst, vürst sajulisel maal..." ; Mõrane kell ; "Nagu põhjatu taevas, öös tummuv ja mustav..." ; Kell ; Maastik ; Päike ; Punajuukselisele kerjustüdrukule ; Luik ; Hämarus ; Mäng ; Somp ja udud ; Pariisi unenägu ; Hommikuhämarik ; Üksildaste vein ; Üks märtritar ; Beatrice ; Aabel ja Kain ; Armastajate surm ; Vaeste surm ; Matk ; Lunahind ; Ühe pilgu lubadused. Eluloolisi andmeid autori kohta lk. 703

  18. Utilidade do coágulo sangüíneo para o isolamento de Sporothrix schenckii de gatos naturalmente infectados

    Directory of Open Access Journals (Sweden)

    Tânia Maria Pacheco Schubach

    2004-11-01

    Full Text Available The diagnosis of disseminated sporotrichosis is usually obtained by necropsy and the isolation of Sporothrix schenckii from blood is rare. Fungemia was shown in vivo through the isolation of S. schenckii from peripheral blood of 13 (n=38, 34.2% cats with naturally acquired sporotrichosis. The coinfection with FIV and with FeLV found, respectively, in 6 (n=34, 17.6% cases and 1 (n=34, 2.9%, apparently did not alter the frequency of the isolation of S. schenckii from peripheral blood. There was agreement of 84.2% comparing these results to the blood culture results simultaneously achieved. In this way, we propose the clot culture as a practical alternative method, efficient and cheap for the diagnosis of disseminated sporotrichosis in cats in vivo.

  19. Contribuição ao estudo da ceruloplasmina I: valôres normais no sôro sangüíneo

    Directory of Open Access Journals (Sweden)

    Francisco B. De Jorge

    1964-12-01

    Full Text Available Foi determinada a atividade cobre-oxidase (ceruloplasmina, pelo método de Houchin, no sôro de 65 indivíduos normais, de raça branca, com idades entre 20 e 45 anos. Foi obtido o seguinte valor médio neste grupo: 33,4 ± ± 3,1 mg/100 ml. Todavia, nos homens (n = 40 a média foi de 32,6 ± 3,1 mg/100 ml, enquanto nas mulheres (n = 25 foi de 34,6 ± 2,8 mg/100 ml; a diferença entre êstes subgrupos é significante. O sôro dialisado em 10 indivíduos normais perdeu 62,8 ± 0,8% da atividade cobre-oxidase. Não encontramos atividade cobre-oxidase na urina de 20 indivíduos normais nem no esperma de 2 outros indivíduos normais.

  20. Détermination des particularités phénotypiques érythrocytaires des donneurs de sang du groupe O de Tlemcen

    OpenAIRE

    BEGHDAD, Mohammed El Amine; ZAZOUA, KHAMES Farid

    2014-01-01

    La transfusion sanguine est une thérapeutique essentielle et incontournable de nos jours, En revanche elle présente des risques directement liés à sa nature même par le transfert de liquide biologique d'un individu à un autre à l'origine des risques infectieux et immunologiques. Ces derniers sont essentiellement dus au polymorphisme génétique des antigènes éiythrocytaires engendrant une alto-immunisation anti-érythrocytaire pouvant aboutir à des situations d'impasse transfusionnel...