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  1. True believers: the recption of Descartes's meditations by Malebranche and Huet

    Directory of Open Access Journals (Sweden)

    D. Anthony Larivière

    2002-12-01

    Full Text Available Both Nicholas Malebranche and Pierre-Daniel Huet were at first positively influenced by Descartes's Meditations, and both came to perceive shortcomings in that work. With respect to mind-body dualism, Malebranche attempted to strengthen Descartes's position by jettisoning clarity and distinctness basing it instead on a principle of intentionality. Huet jettisoned the whole position in favor of skepticism. The source of their different responses lay in their different estimations of Descartes's integrity.Tanto Nicholas Malebranche como Pierre-Daniel Huet foram inicialmente positivamente influenciados pelas Meditações de Descartes e ambos terminaram por perceber falhas nesta obra. No que concerne o dualismo mente e corpo, Malebranche buscou fortalecer a posição cartesiana abandonando o critério de clareza e distinção em favor de um princípio de intencionalidade. Huet abandonou o cartesianismo como um todo em favor do ceticismo. A fonte destas respostas diversas está nas avaliações distintas que fizeram da integridade de Descartes.

  2. Injury rate in a helicopter underwater escape trainer (HUET) from 2005-2012.

    Science.gov (United States)

    Brooks, Christopher J; MacDonald, Conor V; Gibbs, Peter N A

    2014-08-01

    Helicopter underwater escape training (HUET) carries a potential for injury and this paper identifies the injury rate. A marine survival training school registry of all students trained between 2005-2012 in HUET and the coinciding accident records were examined. There were 8902 students trained in a helicopter underwater escape simulator for a total of 59,245 underwater escapes. There were 40 cases where only first-aid was required and 3 serious injuries (a laceration requiring 5 sutures, 1 dislocated shoulder, and 1 water aspiration requiring hospitalization). There were no deaths and no problems reported with using the Emergency Breathing System (EBS) or Air Pocket. Of the injuries, 11 were due to the student using a poor escape technique. The overall probability of injury was 0.74 per 1000 ascents. In HUET training, there is a very low injury rate with almost no significant severity. Although not scientifically proven, this would suggest that the low incident rate is due to good medical screening and the attention given by instructors to anxious students. Compared to other training such as diving, parachute jumping, and submarine escape training, the rate of injury was considerably lower.

  3. Hurricane Isabel Poster (September 18, 2003)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hurricane Isabel poster. Multi-spectral image from NOAA-17 shows Hurricane Isabel making landfall on the North Carolina Outer Banks on September 18, 2003. Poster...

  4. Três biografias quinhentistas da Rainha Santa Isabel

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    Helena Costa Toipa

    2016-12-01

    Full Text Available Dando continuidade aos esforços de canonização de D. Isabel de Aragão, D. João III obteve do Papa, em 1556, a autorização para alargar o culto da já beata D. Isabel a todo o reino. Solicitou, então, aos responsáveis dos mosteiros portugueses, nomeadamente à abadessa do mosteiro de Santa Clara, a composição de uma biografia da rainha, a partir de documentos existentes nesse mosteiro. Surgiram, então, três biografias, todas inspiradas nos referidos documentos: De Vita et Moribus Beatae Elisabethae Lusitaniae Reginae do padre jesuíta Pedro João Perpinhão; Vida e milagres da gloriosa Raynha sancta Ysabel, molher do catholico Rey dom Dinis sexto de Portugal, editada pelos mordomos da Confraria da Rainha Santa Isabel, e “ Vida da Bemaventurada sancta Isabel Raynha de Portugal”, de Frei Marcos de Lisboa, inclusa na Segunda Parte das suas Chronicas da Ordemdos Frades Menores.

  5. Arabis soyeri Reuter ex Huet subsp. soyeri (Brassicaceae en el Pirineo aragonés [Arabis soyeri Reuter & Huet subsp. soyeri (Brassicaceae, in the Aragonese Pyrenees

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    José Vicente FERRÁNDEZ PALACIO

    2012-12-01

    Full Text Available RESUMEN: En esta nota confirmamos la presencia de Arabis soyeri subsp. soyeri en el Pirineo aragonés (provincia de Huesca. Esta cita oscense se sitúa en el límite SW de su área de distribución endémica. Además, comentamos algunos aspectos sobre su autoecología y conservación.SUMMARY: Arabis soyeri Reuter & Huet subsp. soyeri is confirmed for the flora of the Aragonese Pyrenees (Huesca province, Spain. Moreower, this new station is located on the south-western border of its endemic range. Some aspects on its autecology and conservation are discussed as well.

  6. Recent recoveries of archaeological ceramics on Santa Isabel, central Solomon Islands

    International Nuclear Information System (INIS)

    Carter, M.J.; Roe, D.; Keopo, J.

    2012-01-01

    Recent field investigations on Santa Isabel in the Central Solomon Islands have revealed the presence of archaeological pottery in both terrestrial and intertidal contexts. Preliminary dating results and comparative stylistic analyses of sherds provide evidence to suggest an antiquity of ceramics in northwest Isabel spanning the late Holocene to the recent historic past. These research outcomes expand the known distribution of pottery within the Solomon Islands and provide new knowledge about the prehistory of Santa Isabel. Here we describe the Santa Isabel ceramics, and suggest several implications of the research for current settlement models of the Solomon Islands and for our understanding of the variability in the archaeological record of mid- to late-Holocene ceramic distribution throughout the region. (author). 24 refs., 7 figs.

  7. MAGIČNI REALIZEM V TRILOGIJI ISABEL ALLENDE

    OpenAIRE

    Dolinar, Bojana

    2009-01-01

    POVZETEK MAGIČNI REALIZEM V TRILOGIJI ISABEL ALLENDE V diplomski nalogi sem se ukvarjala z analizo magičnega realizma v trilogiji ene najbolj znanih čilskih pisateljic Isabel Allende, ki je tudi predstavnica latinskoameriškega postmodernističnega romana, saj je navzočnost magičnega realizma v njenih delih ena glavnih oblik latinskoameriškega postmodernizma, brez katerega bi njeno trilogijo težko označili za postmodernistično. Trilogija, katero sestavljajo romani Hiša duhov, Hči sreče ...

  8. Hurricane Isabel gives accelerators a severe test

    International Nuclear Information System (INIS)

    Swapan Chattopadhyay

    2004-01-01

    Hurricane Isabel was at category five--the most violent on the Saffir-Simpson scale of hurricane strength--when it began threatening the central Atlantic seaboard of the US. Over the course of several days, precautions against the extreme weather conditions were taken across the Jefferson Lab site in south-east Virginia. On 18 September 2003, when Isabel struck North Carolina's Outer Banks and moved northward, directly across the region around the laboratory, the storm was still quite destructive, albeit considerably reduced in strength. The flood surge and trees felled by wind substantially damaged or even devastated buildings and homes, including many belonging to Jefferson Lab staff members. For the laboratory itself, Isabel delivered an unplanned and severe challenge in another form: a power outage that lasted nearly three-and-a-half days, and which severely tested the robustness of Jefferson Lab's two superconducting machines, the Continuous Electron Beam Accelerator Facility (CEBAF) and the superconducting radiofrequency ''driver'' accelerator of the laboratory's free-electron laser. Robustness matters greatly for science at a time when microwave superconducting linear accelerators (linacs) are not only being considered, but in some cases already being built for projects such as neutron sources, rare-isotope accelerators, innovative light sources and TeV-scale electron-positron linear colliders. Hurricane Isabel interrupted a several-week-long maintenance shutdown of CEBAF, which serves nuclear and particle physics and represents the world's pioneering large-scale implementation of superconducting radiofrequency (SRF) technology. The racetrack-shaped machine is actually a pair of 500-600 MeV SRF linacs interconnected by recirculation arc beamlines. CEBAF delivers simultaneous beams at up to 6 GeV to three experimental halls. An imminent upgrade will double the energy to 12 GeV and add an extra hall for ''quark confinement'' studies. On a smaller scale

  9. Alice'i imedemaa Pariisis / Isabel Chiang

    Index Scriptorium Estoniae

    Chiang, Isabel

    2000-01-01

    1998. a. Pariisis Catherine Alice Mamet' poolt asutatud mööblisalongist, seal tegutsevate disainerite (Pucci de Rossi, Satch, Guy Ferrer, Pablo Pares jt.) loomingunäiteid. Pariisis disaini õppiva tudengi Isabel Chiangi eluloolisi andmeid. 15 illustratsiooni

  10. ISABEL Triggering Sustainable Biogas Energy Communities through Social Innovation

    Science.gov (United States)

    Baumgarten, Wibke; Piedra Garcia, Diego

    2017-04-01

    The Horizon 2020 funding project ISABEL (Triggering Sustainable Biogas Energy Communities through Social Innovation) is all about promoting, supporting and developing community biogas in Europe. The project is set on providing all the framework conditions for biogas communities to shape, develop and thrive. It works on all angles to pave the way for the transition from traditional supply chains to community ownership and take full advantage of the ample societal benefits of regional community-driven biogas systems, fuelled and inspired by Social Innovation principles. The biogas communities emerge in three targeted ISABEL regions, Baden-Württemberg in Germany, Central and Eastern Macedonia and Thrace in Greece and Yorkshire, Lincolnshire and the Humber in UK. To realize this vision ISABEL is employing its "5E strategy" with the following objectives: Educate: Re-position biogas energy by re-branding it as a "public good". Engage: Enable the development of regional Biogas Communities. Empower: Utilize the created momentum through Social Innovation and Public Participation Evaluate: Assess the local interventions and drafting lessons and guidelines Expand: Maximise impact through transfer and replication

  11. The utility of an online diagnostic decision support system (Isabel) in general practice: a process evaluation.

    Science.gov (United States)

    Henderson, Emily J; Rubin, Greg P

    2013-05-01

    To evaluate the utility of Isabel, an online diagnostic decision support system developed by Isabel Healthcare primarily for secondary medical care, in the general practice setting. Focus groups were conducted with clinicians to understand why and how they used the system. A modified online post-use survey asked practitioners about its impact on their decision-making. Normalization process theory (NPT) was used as a theoretical framework to determine whether the system could be incorporated into routine clinical practice. The system was introduced by NHS County Durham and Darlington in the UK in selected general practices as a three-month pilot. General practitioners and nurse practitioners who had access to Isabel as part of the Primary Care Trust's pilot. General practitioners' views, experiences and usage of the system. Seven general practices agreed to pilot Isabel. Two practices did not subsequently use it. The remaining five practices conducted searches on 16 patients. Post-use surveys (n = 10) indicated that Isabel had little impact on diagnostic decision-making. Focus group participants stated that, although the diagnoses produced by Isabel in general did not have an impact on their decision-making, they would find the tool useful if it were better tailored to the primary care setting. Our analysis concluded that normalization was not likely to occur in its current form. Isabel was of limited utility in this short pilot study and may need further modification for use in general practice.

  12. Simulating the formation of Hurricane Isabel (2003) with AIRS data

    Science.gov (United States)

    Wu, Liguang; Braun, Scott A.; Qu, John J.; Hao, Xianjun

    2006-02-01

    Using the AIRS retrieved temperature and humidity profiles, the Saharan Air Layer (SAL) influence on the formation of Hurricane Isabel (2003) is simulated numerically with the MM5 model. The warmth and dryness of the SAL (the thermodynamic effect) is assimilated by use of the nudging technique, which enables the model thermodynamic state to be relaxed to the profiles of the AIRS retrieved data for the regions without cloud contamination. By incorporating the AIRS data, MM5 better simulates the large-scale flow patterns and the timing and location of the formation of Hurricane Isabel and its subsequent track. By comparing with an experiment without nudging of the AIRS data, it is shown that the SAL may have delayed the formation of Hurricane Isabel and inhibited the development of another tropical disturbance to the east. This case study confirms the argument by Dunion and Velden (2004) that the SAL can suppress Atlantic tropical cyclone activity by increasing the vertical wind shear, reducing the mean relative humidity, and stabilizing the environment at lower levels.

  13. STABILITY OF ANTHOCYANINS FROM AGROINDUSTRIAL RESIDUE OF ISABEL GRAPE GROWN IN SÃO FRANCISCO VALLEY, BRAZIL

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    RAFAELLA DA SILVA BASTOS

    Full Text Available ABSTRACT Grape by-products are promising and sustainable sources of anthocyanins. Considering the factors related to degradation of those pigments, spectrophotometric and kinetic analyzes were carried out with the aim to evaluate the light and heat stability of anthocyanins from Isabel grape residue. We found that the exposure to luminosity (80W; 2500 lux and high temperature (= 70ºC significantly affected the absorption and content of those compounds (p <0.05, whose the most stable condition was obtained at 50°C (t1/2: 37.7h; k: 1.84 x 10-2 h-1 and protected from light (t1/2: 3,320.6h; k: 2.09 x 10-4 h-1. Therefore, the anthocyanins from the agroindustrial residue of Isabel grape are an alternative of natural colorants for food that can be packaged in opaque packaging and not subjected to severe heat treatment during processing.

  14. A química na educação da Princesa Isabel Chemistry in Princess Isabel's education

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    Carlos A. L. Filgueiras

    2004-04-01

    Full Text Available The private archive of the Brazilian Imperial Family holds a wealth of little known documents about the education of the daughters of Emperor D. Pedro II, especially of the eldest, Isabel, Princess Imperial. Science, particularly chemistry, for which her father had a particular fondness, occupied an important place in the girl's education. The study of these documents sheds a new light on the contrast between female education in the country in general, during most of the 19th century, and the careful upbringing envisaged by the Emperor for his future successor.

  15. O carbonato de cálcio na desacidificação do vinho Isabel The calcium carbonate in the desacidification of Isabella wine

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    Luiz Antenor Rizzon

    2005-06-01

    Full Text Available A uva Isabel (Vitis labrusca é a cultivar de videira mais difundida na Região Vitícola da Serra Gaúcha. Entre outras finalidades, é utilizada para a elaboração de vinho tinto de mesa, o qual, geralmente, apresenta acidez elevada, devido ao teor de ácido tartárico livre. O objetivo do presente trabalho foi avaliar a influência de diferentes doses de carbonato de cálcio (0,0; 0,5; 1,0; 1,5; 2,0; 2,5 e 3,0 g L-1 na correção da acidez e na composição do vinho Isabel da Serra Gaúcha. O estudo foi realizado na Embrapa Uva e Vinho, em Bento Gonçalves - RS, na safra de 2002. O delineamento experimental utilizado foi o de blocos casualizados, com sete tratamentos e quatro repetições. As análises dos vinhos, realizadas dez dias após o tratamento, constaram da densidade, álcool, acidez total, acidez volátil, pH, açúcares redutores, extrato seco, extrato seco reduzido, cinzas, densidade ótica a 420, 520 e 620 nm, intensidade de cor e coloração, efetuadas através de métodos físico-químicos. O ácido tartárico foi determinado através da cromatografia líquida de alta eficiência (CLAE. O potássio e o cálcio foram analisados por espectrofotometria de absorção atômica. Além da redução da acidez do vinho Isabel, o carbonato de cálcio interferiu na cor, no extrato seco, nas cinzas e no teor de elementos minerais do vinho Isabel.Isabel grape (Vitis labrusca is the variety mostly spread in the Serra Gaúcha Region which is used, among other purposes, to elaborate red table wines. This wine usually presents high acidity, due to the level of free tartaric acid. The purpose of this work was to evaluate the effect of different doses of calcium carbonate in acidity and in the Isabel wine composition of the Serra Gaúcha region. The study carried out at Embrapa Uva e Vinho consisted of application in Isabel wine, from the 2002 vintage, different concentrations of calcium carbonate (0,0; 0,5; 1,0; 1,5; 2,0; 2,5 and 3,0 g L-1. The

  16. Isabel de Villena i família: una reconsideració biogràfica

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    Cantavella, Rosanna

    2015-12-01

    Full Text Available This article aims to systematize the last decades’ historiographical contributions on the life of Isabel de Villena. In the first section it is shown that, far from being a helpless orphan, Enric de Villena’s daughter could rely on a significant net of uncles, aunts and cousins, which helps understand the author’s choice of Franciscanism. The second section analyzes the true reasons why Isabel de Villena, who possessed an important fortune, was brought up in queen Maria’s court when her father, who had been exiled by the Trastámara brothers, died: as the daughter of the last legitimate male descendant of one of the claimants of the throne of Aragon in the aftermath of Martí l’Humà’s death, her future had to be carefully monitored.[ct] Aquest article pretèn sistematitzar les notícies historiogràfiques de les últimes dècades en allò que pot ser aplicat a augmentar el nostre coneixement de la vida d’Isabel de Villena. En primer lloc es mostra que, lluny de ser una orfeneta desvalguda, la fi lla d’Enric de Villena comptava amb una signifi cativa xarxa d’oncles, ties i cosins, i aquesta ajuda a entendre l’opció de l’autora pel franciscanisme. En la segona part s’analitzen les autèntiques raons de per què Isabel de Villena, que comptava amb una considerable fortuna, va ser integrada a la cort de la reina Maria a la mort del seu pare, que havia estat desterrat pels Trastàmares: com a filla de l’últim descendent masculí legítim d’un dels aspirants al tron d’Aragó a la mort de Martí l’Humà, el seu futur havia de ser supervisat amb compte.

  17. Avaliação da uva cv. Isabel para a elaboração de vinho tinto

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    RIZZON Luiz Antenor

    2000-01-01

    Full Text Available A uva Isabel, originária do Sul dos Estados Unidos, é uma das principais cultivares de Vitis labrusca. Atualmente é a cultivar mais difundida na Serra Gaúcha, representando aproximadamente 45% de toda a uva produzida nessa região. Além da elaboração de vinho tinto comum, a Isabel é utilizada para elaboração de vinho rosado e suco e comercializada como uva de mesa. O objetivo do presente trabalho foi determinar as características agronômicas e enológicas da uva Isabel, para elaboração de vinho tinto comum. Para isso, avaliou-se a maturação da uva e realizaram-se estudos para caracterizar o cacho, o mosto e o vinho tinto, nas safras de 1988 a 1994. Os resultados obtidos evidenciaram que a uva Isabel tem cacho pequeno, solto, formado por bagas e sementes grandes. O mosto apresenta cor rosada pouco intensa, tem bom teor de açúcar e baixo nível de ácido málico e acidez total. O vinho tem cor vermelha viva; o aroma é intenso e com acentuada tipicidade varietal; a análise sensorial evidencia que geralmente falta ao vinho equilíbrio e maciez.

  18. Los Levantamientos topográficos-parcelarios de la Junta General de Estadística en Cuenca, Huete y Valdeolivas (1867-1869)

    OpenAIRE

    Vidal Domínguez, Mª Jesús; Camarero Bullón, Concepción

    2014-01-01

    Entre 1867 y 1869, en el marco del proyecto topográfico-catastral diseñado por Francisco Coello, la Junta General de Estadística lleva a cabo el levantamiento de cartografía urbana de nueve localidades no madrileñas, entre ellas tres conquenses: Cuenca, Huete y Valdeolivas, cuya cartografía se conserva en el archivo técnico del Instituto Geográfico Nacional. Se trata de un material de gran valor histórico y calidad técnica. El presente trabajo estudia el marco histórico en que se realiza el l...

  19. La mujer y La comida en Los Cuentos De Eva Luna Estudio Literario Isabel Allende

    OpenAIRE

    GHALI, Sarra

    2016-01-01

    Esta investigación es una aproximación a la literatura de una de las escrituras Hispanoamericanas más influyentes de nuestro tiempo, Isabel Allende. Isabel Allende, nacida en Perú y con nacionalidad chilena, comenzó su literatura en el exilio como una simple carta a su abuelo, que se convirtió en el eje de su ópera prima “La casa de los espíritus” (1982). Con esta obra llena de realismo mágico, se le consideró como una de las escritoras más importantes del post- boom latinoa...

  20. La gastronomía como elemento comunicativo en los personajes de las novelas de Isabel Allende

    OpenAIRE

    Acosta, Yanet

    2011-01-01

    En español: La novelista chilena Isabel Allende entra en la Historia a través de las vidas de la gente, desde la cotidianeidad, por lo que la cocina se convierte en uno de sus principales herramientas de escritura. El estudio de la totalidad de su obra literaria aporta el conocimiento de los recursos que la autora utiliza para conseguirlo. Con esta investigación se demuestra la utilidad que puede tener el aspecto gastronómico en el ejercicio literario.In english: Chilean novelist Isabel Allen...

  1. La asistencia sanitaria en la corte de Isabel de Valois The sanitary care in Isabel de Valois ‘court

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    Guillermo A. Cañadas-De la Fuente

    2007-11-01

    Full Text Available Entre los documentos referentes al funcionamiento de la corte de la reina Isabel de Valois es posible encontrar datos fundamentales para conocer el quehacer de los profesionales médico-sanitarios en el siglo XVI, en este caso circunscritos al ámbito regio. La necesidad de velar por la salud de la Corte resultaba tan relevante como cualquier otro asunto digno de la atención del alto funcionariado encargado de la correcta marcha de los asuntos de Estado. Por este motivo, la gestión y administración de los recursos sanitarios del círculo cortesano generaron una interesante documentación, conservada en la sección Casa y Sitios Reales del Archivo General de Simancas, de la que en este artículo se analiza una significativa muestra.Among the documents concerning the functioning of Queen Isabel de Valois ‘court, it is possible to find fundamental information to know something about the duty of sanitary professionals in the sixteenth century, in this case circumscribe to the royal environment. The necessity to watch over the health of the court was as outstanding as any other matter worthy of the attention of the high civil servants in charge of the correct course in the state affairs. For this reason, the management and administration of the health resources in the court environment generated an interesting documentation preserved in Casa y Sitios Reales of the Archivo General de Simancas, and we will analyze a significant sample of it in this article.

  2. Leachable 226Ra in Philippine phosphogypsum and its implication in groundwater contamination in Isabel, Leyte Philippines

    International Nuclear Information System (INIS)

    Canete, Socrates Jose P.; Palad, Lorna Jean H.; Enriquez, Eliza B.; Garcia, Teofilo Y.; Yulo-Nazarea, Teresa

    2007-01-01

    Phosphogypsum (PG), the major waste material in phosphate fertilizer processing, has been known to contain enhanced levels of naturally-occurring radionuclides especially 226 Ra. The lack of radioactivity data regarding Philippine phosphogypsum and its environmental behavior in the Philippine setting has brought concern on possible contamination of groundwater beneath the phosphogypsum ponds in Isabel, Leyte, Philippines. The radioactivity of Philippine phosphogypsum was determined and the leaching of 226 Ra from phosphogypsum and through local soil was quantified. Level of 226 Ra in groundwater samples in Isabel, Leyte, Philippines was also quantified to address the primary concern. It was found that the 226 Ra activity in Philippine phosphogypsum is distributed in a wide range from 91.5 to 935 Bq/kg. As much as 5% of 226 Ra can be leached from Philippine PG with deionized water. In vitro soil leach experiments suggest that the soil in the phosphate fertilizer plant area would be able to deter the intrusion of 226 Ra into the water table. Compared to reported values of natural groundwater levels of 226 Ra, the concentration of this radionuclide in Isabel, Leyte groundwater suggest that there is no 226 Ra intrusion brought about by the presence of phosphogypsum ponds in the area. (Authors)

  3. Qualidade de uva 'Isabel' tratada com cloreto de cálcio em pós-colheita e armazenada sob atmosfera modificada

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    Rosana Sousa da Silva

    2012-03-01

    Full Text Available Uvas 'Isabel' foram tratadas após a colheita com cloreto de cálcio (CaCl2 e submetidas a atmosfera modificada para avaliação da manutenção de sua qualidade durante o armazenamento, a 12±1 ºC e 85±2% de UR. O experimento foi conduzido em delineamento inteiramente casualizado, em esquema fatorial 5 x 2 x 5, com 3 repetições, sendo cinco doses de CaCl2 (0,0; 0,5; 1,0; 2,0 e 4,0%, dois tipos de atmosfera [ambiente e modificada (AM] e cinco períodos, durante o armazenamento refrigerado. As avaliações foram acidez titulável (AT, sólidos solúveis (SS, relação SS/AT, pH, ácido ascórbico, incidência de podridão, perda de massa, aparência do engaço e índice de degrana. A AM reduziu a perda de massa, a incidência de podridão e manteve a aparência verde do engaço, ampliando a vida útil de uva 'Isabel' em seis dias. Doses de CaCl2 entre 0,5 e 2,0% reduziram a incidência de podridão. A aplicação de CaCl2 associado à AM reduziu a degrana em uva 'Isabel' durante o armazenamento refrigerado.

  4. El mosaico del laberinto de Huete (Cerro de Alvar Fáñez, Cuenca

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    Ana TORRECILLA AZNAR

    2009-08-01

    Full Text Available RESUMEN: En el yacimiento romano de Huete (Cuenca fue encontrado en una estancia de la que parece ser el área pública de la ciudad un mosaico que representaba un motivo de laberinto enmarcado por muralla. Aunque el emblema central no se ha conservado, suponemos que figuraba la lucha entre Teseo y el Minotauro, que nos transporta al mito cretense. Los paralelos conocidos de laberintos se ubican, sobre todo, en la mitad occidental del Imperio Romano, junto con Chipre, pues representan una seña de romanidad, de aceptación de las modas y costumbres romanas. Sin embargo, aunque no son numerosos los ejemplos conocidos en la Península Ibérica, se han documentado en lugares distantes, mostrando la amplia difusión del motivo. En todos los casos se datan entre mediados del s. II d.C. y mediados del s. III d.C. La función de estos mosaicos era no sólo decorativa, sino que se buscaba proteger el edificio que lo albergaba contra los maleficios, al representar la lucha y triunfo del héroe sobre el mal.Actualmente el mosaico se encuentra desaparecido, pero los escasos restos conservados fueron dibujados en los años 70 del siglo pasado. A partir de esta documentación, se ha reconstruido el laberinto que representa y se ha insertado en la planta de la habitación correspondiente, simulando su colocación original. El resto de imágenes muestran paralelos del laberinto o la iconografía de la lucha de Teseo y el Minotauro en soportes diversos (mosaico, cerámica y numismática.ABSTRACT: A mosaic, representing a labyrinth surrounded by a wall, was found in a room that is part of the supposed public area of the city, in the Roman site of Huete (Cuenca. Although the central motif is not kept, we think that it depicted the fight between Theseus and the Minotaur, which leads us to the Cretan myth. The documented parallels of the labyrinth are, above all, from the western half of the Roman Empire, along with Cyprus, because they display a sign of the Roman

  5. Karistus või kasvatus? / Massimiliano Uggeri, Isabel Jimenez, Jarek Kruk, Jaan Sootak ; intervjueerinud Tiina Siimets

    Index Scriptorium Estoniae

    2011-01-01

    Küsimustele, milline karistus tekitab trotsi, millisel sõnal on lapse silmis kaalu ja kuidas paistab see aja mööduses erinevast rahvusest inimestele, vastavad itaallane Massimiliano Uggeri, hispaanlane Isabel Jimenez, poolakas Jarek Kruk ja eestlane Jaan Sootak

  6. Entre muitas histórias: comentários ao texto da autora Maria Isabel Barreno

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    Ivete Lara Camargos Walty

    2001-03-01

    Full Text Available O texto da autora Maria Isabel Barreno aqui apresentado é ele próprio um mapa de vários caminhos, ou fragmentos de mapas, nós de um hipertexto, escritura marcada pela subjetividade autoral em suas diversas possibilidades

  7. Teores de Elementos Minerais e Caracterização Física da Uva Isabel (Vitis labrusca L. Produzida em Boa Vista/RR

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    Magda Márcia Becker

    2014-07-01

    Full Text Available The Roraima viticulture began in 2003 with the creation of the Vale do Rio Branco project, in which the cultivation of grapes was enlarged for a commercial production. However, no information has been found in literature  about the mineral content of grapes produced. Considering the essentiality and importance of this information for human nutrition, quantification of species K by flame photometry and Ca, Fe and Zn by flame atomic absorption spectrometry in pulps of grapes of the Isabel, Vitis labrusca L. variety, cultivated in Boa Vista/RR has been realized, as well as determination of the physical characteristics of the grape bunches and berries. The determinations´ results indicate that K had the highest concentration, followed by Ca, Fe and Zn, being similar to the data, described in other literature sources, except for Ca, which showed smaller, indicating an intervention demand of culture methods employed to optimize the absorption of this species by vines. The consumption of Isabel grape can contribute to the achievement of the adequate intake recommendations of mineral elements. The results of the physical characterization let us classify Isabel grape bunches to very small, loose and green stalks. Overall, this study reveals new data about the physical characteristics and mineral composition present in Isabel grape grown in Boa Vista/RR.

  8. Mujer y melodrama familiar. Una revisión del género en Mi vida sin mí, de Isabel Coixet / Woman and Family Melodrama. My Life Without Me (Isabel Coixet as a Gender/Genre Revision

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    Beatriz Herrero Jiménez

    2016-09-01

    Full Text Available El melodrama clásico, mal entendido como Woman´s Film, construye en la mayoría de sus relatos clásicos a la mujer como significante de pasividad y renuncia. Desde los estudios de género, y más concretamente desde la teoría fílmica feminista, se ha analizado exhaustivamente un subgénero cinematográfico que se entiende como fundamental, ya que saca a la luz las restricciones que les son impuestas a las mujeres en la sociedad patriarcal en general y más concretamente en la institución familiar. Mi vida sin mí (Isabel Coixet, 2003 se enmarca, en apariencia, dentro del corte clásico del subgénero melodramático familiar para subvertir, después, sus propias convenciones. Isabel Coixet se desmarca conscientemente de la identificación masoquista que proporciona el melodrama a la espectadora, critica la representación clásica de la mujer y se aleja de la oposición predominante en el cine entre maternidad-sexualidad. La directora española construye una mujer como sujeto múltiple, contradictorio y en progreso que no se conforma con proponer vías de resistencia a las imposiciones patriarcales, y que no reduce su identidad a la faceta maternal. La mujer del melodrama de Coixet es útil en tanto modelo de identificación diegético y extradiegético para la organización de un nuevo sistema –social, cinemático, etc.– que no ponga sus bases en el binomio dominación-sumisión. Haciendo esto, Isabel Coixet expande los límites del melodrama hasta el terreno del feminismo.Palabras clave: melodrama familiar, Woman´s Film, Women´s Cinema, género, maternidad, patriarcado, espectatoriedad, sexualidad, feminismo.AbstractClassic melodrama, misunderstood as `Woman´s Film´, has usually intented to build women as a signifier of passivity and resignation. Gender Studies, and more specifically Feminist Film Theory, have exhaustively analyzed a subgenre which is understood as an essential one to their aim: family melodrama brings to light

  9. La gastronomía como elemento comunicativo en los personajes de las novelas de Isabel Allende

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    Acosta, Yanet

    2011-12-01

    Full Text Available En español: La novelista chilena Isabel Allende entra en la Historia a través de las vidas de la gente, desde la cotidianeidad, por lo que la cocina se convierte en uno de sus principales herramientas de escritura. El estudio de la totalidad de su obra literaria aporta el conocimiento de los recursos que la autora utiliza para conseguirlo. Con esta investigación se demuestra la utilidad que puede tener el aspecto gastronómico en el ejercicio literario.In english: Chilean novelist Isabel Allende enters history through the lives of people, from everyday life, so the kitchen becomes one of the main tools of writing. The study of all his literary work provides the knowledge of the resources the author used to achieve it. This research demonstrates the utility of gastronomy in the literary exercise.

  10. Gastronomy as a communicative element in the characters in the novels of Isabel Allende

    OpenAIRE

    Janet ACOSTA

    2014-01-01

    Chilean novelist Isabel Allende enters history through the lives of people, from everyday life, so the kitchen becomes one of the main tools of writing. The study of all his literary work provides the knowledge of the resources the author used to achieve it. This research demonstrates the utility of gastronomy in the literary exercise.

  11. Correção do mosto da uva Isabel com diferentes produtos na Serra Gaúcha Must correction of the Isabel grape with different products in the Serra Gaúcha - RS, Brazil

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    Luiz Antenor Rizzon

    2005-04-01

    Full Text Available A uva Isabel da Serra Gaúcha geralmente não alcança teor de açúcar suficiente para produzir vinho equilibrado e, em determinados casos, para atingir 10% v/v de álcool, concentração mínima para vinho de mesa estabelecida pela legislação brasileira. O objetivo do presente trabalho foi avaliar o efeito de diferentes produtos utilizados para correção do mosto na composição química do vinho Isabel. O experimento constou de seis tratamentos: testemunha (sem correção, sacarose, açúcar mascavo, mosto concentrado, álcool vínico e glicose de milho. Os vinhos foram elaborados em microvinificações, com seis repetições. As amostras foram avaliadas através das análises clássicas, efetuadas por métodos físico-químicos, e dos elementos minerais por absorção atômica. A sacarose foi o produto mais adequado para a correção do mosto, pois não incorporou componentes estranhos, não alterou a relação álcool em peso/extrato seco reduzido e apresentou elevado rendimento alcoólico. O álcool vínico pode ser utilizado desde que seja um produto genuíno de procedência garantida, preferencialmente obtido de vinho branco.The cv. Isabel grown in the Serra Gaúcha region in general does not produce a balanced wine, because it sometimes does not reach, the minimum stablished by Brazilian legislation 10% v/v of alcohol. The aim of this work was to evaluate the effects of different products used in the must sugar correction on the chemical composition of the Isabel wine. The experiment had six treatments - control (without correction and correction with saccharose, brown sugar, concentrated must, wine alcohol and mayz glucose; there were six replications. The wine was elaborated by microvinification. The samples were evaluated through classical analysis made by physico-chemical methods and the mineral elements determined by atomic absorption. Results showed that saccharose was the most adequate product for chaptalisation because it did

  12. Gastronomy as a communicative element in the characters in the novels of Isabel Allende

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    Janet ACOSTA

    2014-07-01

    Full Text Available Chilean novelist Isabel Allende enters history through the lives of people, from everyday life, so the kitchen becomes one of the main tools of writing. The study of all his literary work provides the knowledge of the resources the author used to achieve it. This research demonstrates the utility of gastronomy in the literary exercise.

  13. Isabel Allende o la morfología de las voces femeninas

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    Eva Ciuk

    2001-12-01

    Full Text Available Leer obras de la escritora chilena Isabel Allende es como escuchar una composición musical polifónica. Voces que han permanecido ignoradas por los compositores de la gran sinfonía latinoamericana salen del silencio para cantar y contar en voz alta lo que la historiografía y la cultura oficial no les ha permitido expresar. Son voces del silencio, voces de las víctimas del rígido sistema patriarcal, victimas de la violencia y de la brutalidad del régimen dictatorial y voces de los marginados, postergados y excluidos de una colectividad conformista y artificial. En cambio las voces escogidas por la escritora para cantar la melodía principal son las femeninas, voces que en el contexto latinoamericano podian desahogarse sólo en el ámbito cerrado del hogar doméstico. Isabel Allende transforma las mujeres que permanecieron excluidas del gran acontecer histórico, de la vida cotidiana, social, cultural y política de su proprio país en las grandes protagonistas de su obra literaria. La dimensión de la mujer latinoamericana que ha sido relegada al silencio y al olvido, a la pasividad, a la subordinación y resignación emerge aquí con una energía vital y transgresora que transforma las protagonistas en figuras determinadas y subversivas que reclaman para elias una transformación y mejoramiento de sus condiciones de existencia.

  14. Diseño de un plan de marketing para mejorar el posicionamiento de la microempresa que fabrica ropa deportiva, confecciones Isabel del Valle de Tumbaco.

    OpenAIRE

    Cajas Banegas, Cinthya Belén; Pacheco Tonato, Marlene Isabel

    2014-01-01

    This thesis aims to determine the most effective market strategies to achieve the positioning of "Confecciones Isabel", whereas provided that its objective is aimed at notably help the community to offer sports garments made with intelligent fabric. The research aims to develop a "design of a Marketing plan. to improve the positioning of microenterprise "Confecciones Isabel", which will allow to establish strategies and action plans to help microenterprise to position their products and in...

  15. La casa y hacienda de un señor mexica: Un estudio analítico de la “Información de doña Isabel de Moctezuma”

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    Kalyuta, Anastasya

    2008-12-01

    Full Text Available The essay is dedicated to analysis of the “Información de doña Isabel de Moctezuma”, set of documents now belonging to the General Archive of Indies in Seville (Spain. This source is the detailed record of litigation initiated in 1546 by the conquistador Juan Cano de Saavedra on behalf of his wife, Tecuichpochtzin, the daughter of the last Prehispanic Mexica ruler Motecuhzoma Xocoyotzin who after the baptism was called doña Isabel de Moctezuma. The objective of litigation was the restitution of vast land holdings, buildings and objects of value, claimed to be doña Isabel “patrimony” (patrimonio that is the property which she was to inherit from her parents and grandparents, members of the royal dynasty of Tenochtitlan, outlost during the Spanish conquest. The richness of the historical data contained in “Información de doña Isabel de Moctezuma” makes it invaluable source for study of such important topics as the land tenure and matrimonial alliances of the Prehispanic Mexica nobility and subsequent response of their descendants to the challenge of the Colonial period.

    El ensayo se dedica al análisis de los datos contenidos en la “Información de doña Isabel de Moctezuma”, una serie de documentos que constituyen un testimonio detallado del litigio iniciado en 1546 por el conquistador Juan Cano de Saavedra en nombre de su esposa Tecuichpoctzin, bautizada como doña Isabel, hija de Motecuhzoma Xocoyotzin, el ultimo gobernante prehispánico de los mexicas. La meta del litigio consistió en la restitución de las tierras, edificios y objetos de valor declarados patrimonio de doña Isabel, que ella debía heredar de sus padres y abuelos, miembros del linaje gobernante de Tenochtitlan. La riqueza de datos históricos que nos presenta esta fuente la hace indispensable para el estudio, por un lado, de la tenencia de tierra entre la nobleza mexica prehispánica y, por el otro, de sus alianzas matrimoniales y de las

  16. Acidez na vinificação em tinto das uvas Isabel, Cabernet Sauvignon e Cabernet Franc

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    Rizzon Luiz Antenor

    2002-01-01

    Full Text Available A acidez é uma das características gustativas mais importantes dos vinhos e influencia sua estabilidade e coloração. Devido à insolubilização do ácido tartárico sob a forma de sais, a acidez titulável e o pH podem ser alterados durante a vinificação de acordo com o teor de potássio da uva. Este trabalho avaliou a evolução da acidez durante a vinificação de três cultivares de uvas tintas (Isabel - Vitis labrusca -, Cabernet Sauvignon e Cabernet Franc - Vitis vinifera da Serra Gaúcha. Os vinhos foram elaborados por microvinificação na safra de 1995, sendo avaliados a evolução da acidez titulável, pH, ácido tartárico e potássio imediatamente após o esmagamento da uva, na descuba e após a fermentação alcoólica, a fermentação malolática e a estabilização tartárica, totalizando análises em cinco fases da vinificação. Os resultados mostraram uma evolução diferente da acidez, avaliados através do pH, da acidez titulável, do ácido tartárico e do potássio, na vinificação em tinto da uva Isabel em relação à Cabernet Sauvignon e à Cabernet Franc, nas fases compreendidas entre o esmagamento da uva e a descuba. O vinho Isabel se caracterizou por apresentar teores mais elevados de acidez titulável e ácido tartárico e mais baixos de potássio e pH, em relação aos vinhos Cabernet Sauvignon e Cabernet Franc.

  17. Una principessa azteca: Tecuichpotzin Ichcaxochitzin – Isabel de Moctezuma

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    Rosa Maria Grillo

    2016-12-01

    Full Text Available In the framework of the ‘gender studies’ dedicated to forgotten women in history, a prominent place is occupied by Tecuichpotzin Ichcaxochitzin (“Cotton flower, the revered daughter of the lord”   daughter of Moctezuma II, was probably born at the end of the first decade of the sixteenth century. Baptized as Isabel de Moctezuma, she lived a life straddling two worlds and two eras: daughter and wife of kings, repudiated by Cortés, she is sometimes described as the anti Malinche, loyal to her people but perfectly integrated in the colonial system. This paper will compare different sources – historical chronicles of that time and subsequent periods, historical fiction   in order to provide a credible profile and to correctly interpret such contradictory comments and opinions.

  18. Polifenóis totais e avaliação sensorial de suco de uvas Isabel tratadas com ultrassom Phenolic compounds and sensory evaluation of juice from Isabel grapes treated with ultrasound

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    Carine Glaucia Comarella

    2012-05-01

    Full Text Available O suco de uva no Brasil é um produto amplamente consumido por suas características sensoriais e nutricionais; porém, tratamentos durante o seu processamento podem ocasionar perdas de compostos fenólicos importantes na definição dessas características. O ultrassom é apontado como um possível elicitor desses compostos, visto que o estresse mecânico provocado por cavitação acústica e microagitação estimula respostas de defesa na planta que levam à síntese dessas substâncias. Neste estudo, diferentes densidades de potência (53 e 113 W.cm-2 e tempos de exposição (1, 5 e 10 minutos de ultrassom foram aplicados em uvas Isabel e seu efeito sobre o conteúdo de polifenóis totais e o aspecto sensorial dos sucos foi avaliado. O ultrassom causou um acréscimo de até 83% no teor de polifenóis totais, melhorando também as características sensoriais dos sucos, tendo sido estes os preferidos pelos provadores.Grape juice in Brazil is a product widely consumed for their sensory and nutritional characteristics, however, treatments during processing can cause loss of phenolic compounds important in defining these characteristics. Ultrasound is cited as a possible elicitor of these compounds, since the mechanical stress caused by acoustic cavitation and microstreaming stimulates the plant defense responses that lead to synthesis of these substances. In this study, different power densities (53 and 113 W.cm-2 and exposure times (1, 5 and 10 minutes of ultrasound were applied in Isabel grapes and its effect on the total polyphenols content and sensory aspect of the juices was evaluated. The ultrasound caused an increase of up to 83% in total polyphenols content, improving the sensory characteristics of juices, being chosen as preferred by the tasters.

  19. Extração, secagem por atomização e microencapsulamento de antocianinas do bagaço da uva "Isabel" (Vitis labrusca Extraction, spray drying and microencapsulating of 'Isabel' grape (Vitis labrusca bagasse anthocyanin

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    Eunice Valduga

    2008-10-01

    Full Text Available Objetivou-se obter neste trabalho um corante natural (antocianina, na forma de pó a partir do bagaço de uva da cultivar "Isabel" (Vitis labrusca, onde foram realizados estudos de extração e encapsulamento. Empregou-se o método de extração por imersão mediante técnica de planejamento experimental, onde as variáveis avaliadas foram pH da solução de extração (1-2, volume de etanol (100-250 mL, tempo de extração (3-7 h e temperatura de extração (15-35ºC. A concentração máxima de antocianinas totais obtidas foi de 300 mg/100 g de bagaço de uva (umidade 5% nos níveis inferiores de pH (1,0 e tempo (3 horas e superiores de temperatura (35ºC e volume de etanol (250 mL. Os extratos foram secos por atomização. A melhor condição para o encapsulamento e a secagem foi quando utilizaram-se proporções iguais de maltodextrina e goma arábica.This work had the aim of obtaining a natural pigment (anthocyanin at powder form from 'Isabel' grape bagasse (Vitis labrusca, studying the extraction and encapsulating steps one applied the method of extraction by immersion by experimental design technique, when the factors investigated were pH of the extraction solution (1-2, volume of ethanol (100-250 mL, extraction time (3-7 h and extraction temperature (15-35 °C. The maximum concentration of total anthocyanin was 300 mg/100g of grape bagasse (5% moisture at the lower levels of pH (1.0 and time (3 h, and at upper levels of temperature (35ºC and amount of ethanol (250 mL. The extracts were dried by a spray process. The best condition for encapsulating and drying was obtained when equal amounts of maltodextrin and Arabic gum were used.

  20. Population screening for glucose-6-phosphate dehydrogenase deficiencies in Isabel Province, Solomon Islands, using a modified enzyme assay on filter paper dried bloodspots

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    Landry Losi

    2010-08-01

    Full Text Available Abstract Background Glucose-6-phosphate dehydrogenase deficiency poses a significant impediment to primaquine use for the elimination of liver stage infection with Plasmodium vivax and for gametocyte clearance, because of the risk of life-threatening haemolytic anaemia that can occur in G6PD deficient patients. Although a range of methods for screening G6PD deficiency have been described, almost all require skilled personnel, expensive laboratory equipment, freshly collected blood, and are time consuming; factors that render them unsuitable for mass-screening purposes. Methods A published WST8/1-methoxy PMS method was adapted to assay G6PD activity in a 96-well format using dried blood spots, and used it to undertake population screening within a malaria survey undertaken in Isabel Province, Solomon Islands. The assay results were compared to a biochemical test and a recently marketed rapid diagnostic test. Results Comparative testing with biochemical and rapid diagnostic test indicated that results obtained by filter paper assay were accurate providing that blood spots were assayed within 5 days when stored at ambient temperature and 10 days when stored at 4 degrees. Screening of 8541 people from 41 villages in Isabel Province, Solomon Islands revealed the prevalence of G6PD deficiency as defined by enzyme activity Conclusions The assay enabled simple and quick semi-quantitative population screening in a malaria-endemic region. The study indicated a high prevalence of G6PD deficiency in Isabel Province and highlights the critical need to consider G6PD deficiency in the context of P. vivax malaria elimination strategies in Solomon Islands, particularly in light of the potential role of primaquine mass drug administration.

  1. Optimization of the HS-SPME-GC/MS technique for determining volatile compounds in red wines made from Isabel grapes (Vitis labrusca

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    Narciza Maria de Oliveira ARCANJO

    2015-01-01

    Full Text Available AbstractBrazilian wine production is characterized by Vitis labrusca grape varieties, especially the economically important Isabel cultivar, with over 80% of its production destined for table wine production. The objective of this study was to optimize and validate the conditions for extracting volatile compounds from wine with the solid-phase microextraction technique, using the response surface method. Based on the response surface analysis, it can be concluded that the central point values maximize the process of extracting volatile compounds from wine, i.e., an equilibrium time of 15 minutes, an extraction time of 35 minutes, and an extraction temperature of 30 °C. Esters were the most numerous compounds found under these extraction conditions, indicating that wines made from Isabel cultivar grapes are characterized by compounds that confer a fruity aroma; this finding corroborates the scientific literature.

  2. The Power of Love: Rewriting the Romance in Isabel Allende's The House of the Spirits and Eva Luna

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    Frances Jane P. Abao

    2000-12-01

    Full Text Available Despite its ongoing popularity with women readers, romantic fiction has traditionally been regarded as an instrument of women's oppression, largely due to its reinforcement and even glorification of sexual stereotypes and bourgeois values. Latin American writer Isabel Allende's novels The House of the Spirits and Eva Luna both contain a number of the elements and conventions of romantic fiction, including distinct similarities to the two acknowledged foundations of this genre: Charlotte Brontë's Jane Eyre and Emily Brontë's Wuthering Heights.However, The House of the Spirits and Eva Luna can also be read as rewritings of the genre of romantic fiction. In these two texts, Isabel Allende appropriates and then reworks certain conventions of romantic fiction in order to portray her notion of "fulfilling egalitarian relationships" between men and women. Nevertheless, despite these feminist revisions, Allende's rewritten romances do retain the "wish-fulfillment" element-or ideal-of romantic fiction, its depiction of women's fantasy of feminine values being appreciated and validated within heterosexual romantic relationships in the real world.

  3. Efeito da safra vitícola na composição da uva, do mosto e do vinho Isabel da Serra Gaúcha, Brasil

    OpenAIRE

    Rizzon,Luiz Antenor; Miele,Alberto

    2006-01-01

    Entre os fatores que interferem na composição e na qualidade do vinho, destaca-se a safra vitícola, com suas variações climáticas. Com este objetivo, avaliou-se o efeito das safras de 1999, 2000 e 2001 na composição da uva, do mosto e do vinho Isabel da Serra Gaúcha. Nesse sentido, foram selecionados vinte e dois produtores de uva Isabel de onze municípios dessa região. Por ocasião da maturação, para as avaliações da uva e do mosto e a elaboração das microvinificações, foram colhidos 60kg de ...

  4. CANALES, SIFONES Y ALMENARAS. EL IMPACTO AMBIENTAL DE LAS INFRAESTRUCTURAS DEL CANAL DE ISABEL II (MADRID

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    José A. Sotelo Navalpotro

    2013-01-01

    Full Text Available El presente artículo tiene como finalidad, valorar el impacto ambiental de las conducciones del Canal de Isabel II en el contexto del paisaje. Partimos de la idea según la cual, las infraestructuras del Canal de Isabel II, y más que formar parte del paisaje por el que se extienden, son el propio paisaje. Nuestra zona de estudio es el noroeste de la Comunidad de Madrid (síntesis de la interacción de los propios agentes naturales, de la ocupación humana y de los usos del suelo, área a la que nos aproximarnos a través de la investigación de la integración paisajística, entendida ésta como una estrategia de intervención en el territorio, que tiene como objetivo principal orientar las transformaciones del paisaje o corregir las ya realizadas, para conseguir su adaptación al propio paisaje. En definitiva, nos encontramos ante la necesidad de ajustar un objeto o actuación territorial a las características fisonómicas de un paisaje dado, o de algunos de sus componentes, así como a su carácter y a sus contenidos semánticos.

  5. Las relaciones hispano-británicas durante el reinado de Isabel II

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    Gemma Alonso Torres

    1995-01-01

    Full Text Available A lo largo de casi todo el siglo xix, la política de España estuvo hipotecada en manos de los gobiernos francés y, preferentemente, inglés. Este hecho supuso una dependencia total de París y Londres. Los acontecimientos políticos provocados por las guerras carlistas, la subida al trono de Isabel II y posterior reconocimiento de la reina, causaron un déficit en las arcas del Tesoro español, lo que motivó un endeudamiento continuo que se plasmó en la emisión de Deuda pública, adquirida por subditos belgas, holandeses, franceses y principalmente ingleses.

  6. Reseña del libro "New Approaches to Specialized English Lexicology and Lexicography" de Isabel Balteiro (ed.)

    OpenAIRE

    Edo Marzá, Nuria

    2012-01-01

    The book New Approaches to Specialized English Lexicology and Lexicography, edited by Isabel Balteiro, is a collection of eleven relevant contributions aimed at analysing English and EsP lexicology and lexicography and relating them to other linguistic and non-linguistic disciplines. In fact, one of its main strengths is the fact that it links these areas with less academic or prototypically linguistic fields such as comics, fashion and even cinema.

  7. A Perda de um(a) Filho(a) Jovem no Romance Paula, de Isabel Allende

    OpenAIRE

    Cazanatto, Elenice; Martta, Margareth Kuhn

    2014-01-01

    O adoecimento e a perda de um filho são situações não naturalmente esperadas na perspectiva do ciclo vital, provocando uma ruptura na vida dos pais, despertando sentimentos intensos e muito sofrimento. No romance autobiográficoPaula,a autora Isabel Allende escreve para a filha que estava internada na UTI de um hospital, há alguns meses, com um diagnóstico pouco favorável. O presente artigo trata de uma leitura psicanalítica sobre a perda de um (a) filho (a) adulto-jovem, tomando como objeto d...

  8. Influences of the Saharan Air Layer on the Formation and Intensification of Hurricane Isabel (2003): Analysis of AIRS data and Numerical Simulation

    Science.gov (United States)

    Wu, L.; Braun, S. A.

    2006-12-01

    Over the past two decades, little advance has been made in prediction of tropical cyclone intensity while substantial improvements have been made in forecasting hurricane tracks. One reason is that we don't well understand the physical processes that govern tropical cyclone intensity. Recent studies have suggested that the Saharan Air Layer (SAL) may be yet another piece of the puzzle in advancing our understanding of tropical cyclone intensity change in the Atlantic basin. The SAL is an elevated mixed layer, forming as air moves across the vast Sahara Desert, in particular during boreal summer months. The SAL contains warm, dry air as well as a substantial amount of mineral dust, which can affect radiative heating and modify cloud processes. Using the retrieved temperature and humidity profiles from the AIRS suite on the NASA Aqua satellite, the SAL and its influences on the formation and intensification of Hurricane Isabel (2003) are analyzed and simulated with MM5. When the warmth and dryness of the SAL (the thermodynamic effect) is considered by relaxing the model thermodynamic state to the AIRS profiles, MM5 can well simulate the large-scale flow patterns and the activity of Hurricane Isabel in terms of the timing and location of formation and the subsequent track. Compared with the experiment without nudging the AIRS data, it is suggested that the simulated SAL effect may delay the formation and intensification of Hurricane Isabel. This case study generally confirms the argument by Dunion and Velden (2004) that the SAL can suppress Atlantic tropical cyclone activity by increasing the vertical wind shear, reducing the mean relative humidity, and stabilizing the environment at lower levels.

  9. The Relationship of Stated Learning Preferences, Personality Type, and Career Background to Academic and Leadership Performance at the United States Air Command and Staff College

    Science.gov (United States)

    1999-12-11

    Kolb envisioned experiential 26 Table 2 Subscales on the NASSP Learning Styles Profile Cognitive Styles Perceptual Responses Analytic Skill...Research Type Theory and Learning Preferences Jung and the Theory of Psychological Types Isabel Briggs Myers’ Contribution to Jung’s Work The Myers...Implications Recommendations for Further Study Summary of Specific Conclusions Discussion Grounded Curriculum Learning Preferences Type Theory Student

  10. Prevalencia de alergia alimentaria y sensibilización a leche, maní y camarón en adolescentes de octavo y noveno de básica de Cuenca y Santa Isabel

    OpenAIRE

    Ramírez Jimbo, Patricia Liliana

    2015-01-01

    La alergia alimentaria es una respuesta inmunológica a la ingestión de ciertos alimentos, los síntomas varían desde leves hasta fatales. El objetivo de este trabajo es reportar la prevalencia de alergia alimentaria y sensibilización a leche, maní y camarón en adolescentes de octavo y noveno de básica de Cuenca y Santa Isabel. El estudio fue descriptivo transversal realizado en 1008 adolescentes de Cuenca y 500 de Santa Isabel, mediante la aplicación de encuestas y test cutáneos. El alérgeno m...

  11. Influences of Appalachian orography on heavy rainfall and rainfall variability associated with the passage of hurricane Isabel by ensemble simulations

    Science.gov (United States)

    Oldaker, Guy; Liu, Liping; Lin, Yuh-Lang

    2017-12-01

    This study focuses on the heavy rainfall event associated with hurricane Isabel's (2003) passage over the Appalachian mountains of the eastern United States. Specifically, an ensemble consisting of two groups of simulations using the Weather Research and Forecasting model (WRF), with and without topography, is performed to investigate the orographic influences on heavy rainfall and rainfall variability. In general, the simulated ensemble mean with full terrain is able to reproduce the key observed 24-h rainfall amount and distribution, while the flat-terrain mean lacks in this respect. In fact, 30-h rainfall amounts are reduced by 75% with the removal of topography. Rainfall variability is also significantly increased with the presence of orography. Further analysis shows that the complex interaction between the hurricane and terrain along with contributions from varied microphysics, cumulus parametrization, and planetary boundary layer schemes have a pronounced effect on rainfall and rainfall variability. This study follows closely with a previous study, but for a different TC case of Isabel (2003). It is an important sensitivity test for a different TC in a very different environment. This study reveals that the rainfall variability behaves similarly, even with different settings of the environment.

  12. ¿Hacia el fin de la itinerancia? Isabel I de Castilla

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    Mª Isabel DEL VAL VALDIVIESO

    2009-05-01

    Full Text Available Aunque ciertos organismos de la administración del reino están ya asentados en determinados lugares, y se observan algunos indicios de sedentarización, entre ellos el establecimiento de la casa del príncipe Juan en Almazán, la corte de Isabel la Católica sigue siendo itinerante como la de sus antecesores. Con el fin de constatar esta circunstancia, en el presente artículo se estudia el trayecto seguido por Isabel I de Castilla en dos ocasiones, el primer año de reinado, y el último viaje que realiza. En 1475 el espacio recorrido se extiende entre Palencia y Toledo, se trata de un periplo con ida (hacia el Sur y regreso al norte del Duero. En 1503, el viaje se desarrolla entre Alcalá de Henares y Medina del Campo, villa en la que morirá la reina Católica el 26 de noviembre de 1504. En ambas ocasiones, la reina atiende todos los asuntos del gobierno de sus reinos allí donde se encuentre.Malgré l’installation de certains organes de l’administration du royaume dans des lieux précis et quelques indices de sédentarisation, comme l’établissement de la maison du Prince Juan à Almazán, la cour d’Isabelle la Catholique est, comme celle de ses prédécesseurs, itinérante. Cet article se propose d’étudier deux trajets parcourus par Isabelle Ire de Castille : celui qu’elle réalise au cours de la première année de son règne, et le dernier. En 1475, l’espace parcouru s’étend de Palencia à Tolède ; il s’agit d’un trajet vers le sud pour l’aller et au nord du Duero pour le retour. En 1503, le voyage se déroule entre Alcalá de Henares et Medina del Campo, où la reine meurt le 26 novembre 1504. Lors de ces deux déplacements, la reine administre son royaume de l’endroit où elle se trouve.

  13. Mariano Bellver (1817-1876, escultor de cámara de Isabel II

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    Melendreras Gimeno, José Luis

    2002-09-01

    Full Text Available Hijo de Francisco Bellver y Llop, también escultor como su padre. Nació en Madrid en 1817, estudiando en la Real Academia de Bellas Artes de San Fernando, siendo discípulo en esta noble institución del escultor de Cámara José Tomás. Mariano Bellver contribuyó de forma activa al esplendor del Liceo Artístico y Literario de Madrid. Realizó numerosos trabajos, logrando una pública consideración de sus obras. Fue nombrado escultor de Cámara Honorario de Isabel II, jurando su cargo el 3 de mayo de 1860, ante don Buenaventura Carlos Arriban, Comendador de Número de la Real Casa y de la Orden de Carlos III, Jefe Superior de la Administración, Jubilado y Secretario de la Intendencia General de la Real Casa y Patrimonio.…

  14. Ressenya a Grifoll, Isabel, Julián Acebrón, Flocel Sabaté (eds. (2014: Cartografies de l’ànima. Identitat, memòria i escriptura, Lleida, Pagès Editors, 2014, 248 pàgs. ISBN:978-84-9975-517-5; i Acebrón, Julián, Isabel Grifoll, Flocel Sabaté (eds. (2015: La Construcció d’identitats imaginades. Literatura medieval i ideologia, Lleida, Pagès Editors, 2015, 320 pàgs. ISBN:978-84-9975-704-9

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    Vicent Martines

    2016-12-01

    Full Text Available Review to Grifoll, Isabel, Julián Acebrón, Flocel Sabaté (eds. (2014: Cartografies de l’ànima. Identitat, memòria i escriptura, Lleida, Pagès Editors, 2014, 248 pàgs. ISBN:978-84-9975-517-5; and Acebrón, Julián, Isabel Grifoll, Flocel Sabaté (eds. (2015: La Construcció d’identitats imaginades. Literatura medieval i ideologia, Lleida, Pagès Editors, 2015, 320 pàgs. ISBN:978-84-9975-704-9

  15. Acidez na vinificação em tinto das uvas Isabel, Cabernet Sauvignon e Cabernet Franc

    OpenAIRE

    Rizzon Luiz Antenor; Miele Alberto

    2002-01-01

    A acidez é uma das características gustativas mais importantes dos vinhos e influencia sua estabilidade e coloração. Devido à insolubilização do ácido tartárico sob a forma de sais, a acidez titulável e o pH podem ser alterados durante a vinificação de acordo com o teor de potássio da uva. Este trabalho avaliou a evolução da acidez durante a vinificação de três cultivares de uvas tintas (Isabel - Vitis labrusca -, Cabernet Sauvignon e Cabernet Franc - Vitis vinifera) da Serra Gaúcha. Os vinho...

  16. Phenology of pea crop (Pisum sativum L. var. Santa Isabel) in the Bogotá plateau at open field and under plastic cover

    International Nuclear Information System (INIS)

    Galindo Pacheco, J.R.; Clavijo Porras, J.

    2009-01-01

    The assessment of environment effects on plant development is important to identify suitable zones and schedule crop production. In this research, plant development of pea (Pisum sativum L. var. Santa Isabel) was evaluated under Bogotá flat highland, Colombia, environmental conditions (2640 m over sea level, 14°C, 80% R.H., rainfall of 800 mm/year). Two experiments were done under plastic cover [es

  17. Effects of Aquifer Development and Changes in Irrigation Practices on Ground-Water Availability in the Santa Isabel Area, Puerto Rico

    Science.gov (United States)

    Kuniansky, Eve L.; Gómez-Gómez, Fernando; Torres-Gonzalez, Sigfredo

    2003-01-01

    The alluvial aquifer in the area of Santa Isabel is located within the South Coastal Plain aquifer of Puerto Rico. Variations in precipitation, changes in irrigation practices, and increasing public-supply water demand have been the primary factors controlling water-level fluctuations within the aquifer. Until the late 1970s, much of the land in the study area was irrigated using inefficient furrow flooding methods that required large volumes of both surface and ground water. A gradual shift in irrigation practices from furrow systems to more efficient micro-drip irrigation systems occurred between the late 1970s and the late 1980s. Irrigation return flow from the furrow-irrigation systems was a major component of recharge to the aquifer. By the early 1990s, furrow-type systems had been replaced by the micro-drip irrigation systems. Water levels declined about 20 feet in the aquifer from 1985 until present (February 2003). The main effect of the changes in agricultural practices is the reduction in recharge to the aquifer and total irrigation withdrawals. Increases in ground-water withdrawals for public supply offset the reduction in ground-water withdrawals for irrigation such that the total estimated pumping rate in 2003 was only 8 percent less than in 1987. Micro-drip irrigation resulted in the loss of irrigation return flow to the aquifer. These changes resulted in lowering the water table below sea level over most of the Santa Isabel area. By 2002, lowering of the water table reversed the natural discharge along the coast and resulted in the inland movement of seawater, which may result in increased salinity of the aquifer, as had occurred in other parts of the South Coastal Plain. Management alternatives for the South Coastal Plain aquifer in the vicinity of Santa Isabel include limiting groundwater withdrawals or implementing artificial recharge measures. Another alternative for the prevention of saltwater intrusion is to inject freshwater or treated sewage

  18. The Tourism Carrying Capacity of Underwater Trails in Isabel Island National Park, Mexico

    Science.gov (United States)

    Ríos-Jara, Eduardo; Galván-Villa, Cristian Moisés; Rodríguez-Zaragoza, Fabián Alejandro; López-Uriarte, Ernesto; Muñoz-Fernández, Vicente Teófilo

    2013-08-01

    The popularity of ecotourism in the marine protected areas of Mexico has increased over the last 10 years; in particular there is a large development of a SCUBA diving industry in the Mexican Pacific including Isabel Island. Given the risks associated with human activity in the marine environments around this island, we propose two ecotourism management strategies: (1) the creation and use of underwater trails, and (2) the estimation of the specific tourism carrying capacity (TCC) for each trail. Six underwater trails were selected in sites that presented elements of biological, geological, and scenic interest, using information obtained during field observations. The methodology used to estimate the TCC was based upon the physical and biological conditions of each site, the infrastructure and equipment available, and the characteristics of the service providers and the administrators of the park. Correction factors of the TCC included elements of the quality of the visit and the threat and vulnerability of the marine environment of each trail (e.g., divers' expertise, size and distance between groups of divers, accessibility, wind, coral coverage). The TCC values ranged between 1,252 and 1,642 dives/year/trail, with a total of 8,597 dives/year for all six trails. Although these numbers are higher than the actual number of recreational visitors to the island (~1,000 dives per year), there is a need for adequate preventive management if the diving sites are to maintain their esthetic appeal and biological characteristics. Such management might be initially directed toward using only the sites and the TCC proposed here.

  19. The tourism carrying capacity of underwater trails in Isabel Island National Park, Mexico.

    Science.gov (United States)

    Ríos-Jara, Eduardo; Galván-Villa, Cristian Moisés; Rodríguez-Zaragoza, Fabián Alejandro; López-Uriarte, Ernesto; Muñoz-Fernández, Vicente Teófilo

    2013-08-01

    The popularity of ecotourism in the marine protected areas of Mexico has increased over the last 10 years; in particular there is a large development of a SCUBA diving industry in the Mexican Pacific including Isabel Island. Given the risks associated with human activity in the marine environments around this island, we propose two ecotourism management strategies: (1) the creation and use of underwater trails, and (2) the estimation of the specific tourism carrying capacity (TCC) for each trail. Six underwater trails were selected in sites that presented elements of biological, geological, and scenic interest, using information obtained during field observations. The methodology used to estimate the TCC was based upon the physical and biological conditions of each site, the infrastructure and equipment available, and the characteristics of the service providers and the administrators of the park. Correction factors of the TCC included elements of the quality of the visit and the threat and vulnerability of the marine environment of each trail (e.g., divers' expertise, size and distance between groups of divers, accessibility, wind, coral coverage). The TCC values ranged between 1,252 and 1,642 dives/year/trail, with a total of 8,597 dives/year for all six trails. Although these numbers are higher than the actual number of recreational visitors to the island (~1,000 dives per year), there is a need for adequate preventive management if the diving sites are to maintain their esthetic appeal and biological characteristics. Such management might be initially directed toward using only the sites and the TCC proposed here.

  20. Changes in vector species composition and current vector biology and behaviour will favour malaria elimination in Santa Isabel Province, Solomon Islands

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    Beebe Nigel W

    2011-09-01

    Full Text Available Abstract Background In 2009, Santa Isabel Province in the Solomon Islands embarked on a malaria elimination programme. However, very little is known in the Province about the anopheline fauna, which species are vectors, their bionomics and how they may respond to intensified intervention measures. The purpose of this study was to provide baseline data on the malaria vectors and to ascertain the possibility of successfully eliminating malaria using the existing conventional vector control measures, such as indoor residual spraying (IRS and long-lasting insecticidal nets (LLIN. Methods Entomological surveys were undertaken during October 2009. To determine species composition and distribution larval surveys were conducted across on the whole island. For malaria transmission studies, adult anophelines were sampled using human landing catches from two villages - one coastal and one inland. Results Five Anopheles species were found on Santa Isabel: Anopheles farauti, Anopheles hinesorum, Anopheles lungae, Anopheles solomonis, and Anopheles nataliae. Anopheles hinesorum was the most widespread species. Anopheles farauti was abundant, but found only on the coast. Anopheles punctulatus and Anopheles koliensis were not found. Anopheles farauti was the only species found biting in the coastal village, it was incriminated as a vector in this study; it fed early in the night but equally so indoors and outdoors, and had a low survival rate. Anopheles solomonis was the main species biting humans in the inland village, it was extremely exophagic, with low survival rates, and readily fed on pigs. Conclusion The disappearance of the two major vectors, An. punctulatus and An. koliensis, from Santa Isabel and the predominance of An. hinesorum, a non-vector species may facilitate malaria elimination measures. Anopheles farauti was identified as the main coastal vector with An. solomonis as a possible inland vector. The behaviour of An. solomonis is novel as it has

  1. Memórias, histórias e representações sociais do bairro de Vila Isabel e de uma de suas favelas (RJ, Brasil Memories, stories and social representations of the district of Vila Isabel and one of its slums (RJ, Brazil

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    Fernanda Delvalhas Piccolo

    2009-05-01

    Full Text Available A partir da etnografia realizada num Centro Comunitário do Morro dos Macacos, localizado no bairro de Vila Isabel, na cidade do Rio de Janeiro (Brasil, o presente artigo discute a história e a memória do morro e do bairro, explorando alguns eventos realizados nesses locais, que ora reforçam a história e a memória oficiais, ora ressaltam outras versões e memórias existentes e, por vezes, divergentes. Esses eventos interessam como expressões simbólicas dos indivíduos e grupos, ao darem visibilidade às redes de relações, por reforçarem pertencimentos e criarem laços sociais. Importam por contribuírem para a criação de histórias e memórias - oficiais e não-oficiais - que atuam na construção de identidades e representações sociais que, por sua vez, orientam as práticas dos moradores dessas localidades.Based on an ethnography carried out in a community center in Morro dos Macacos, located in Bairro de Vila Isabel, a district in the Northern section of Rio de Janeiro city (Brazil, the present article is about the history and memories of that slum and neighborhood. It examines some events that reinforce its official history and memory or emphasize other stories and memories, different or alike. Those events are interesting symbolical expressions of individuals and groups, for they give visibility to social networks, since they reinforce a sense of belonging to a group and create social links. They are also important for contributing to create stories and memories - official and unofficial - that build social identities and representations that guide its inhabitants’ practices.

  2. Aspectos sociopolíticos da epidemia de toxoplasmose em Santa Isabel do Ivaí (PR Socio-political aspects of toxoplasmosis epidemic in Santa Isabel do Ivaí, Paraná State, Brazil

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    Márcio José de Almeida

    2011-01-01

    Full Text Available Em 2002, o município de Santa Isabel do Ivaí (PR, em virtude de uma epidemia de toxoplasmose, tornou-se lócus privilegiado de investigações sanitárias. As informações disponíveis indicam tratar-se da maior já registrada no mundo: 426 pessoas apresentaram sorologia sugestiva de infecção aguda por T. gondii (IgM reator. Esta pesquisa foi realizada com o objetivo de identificar as ações desenvolvidas pelos serviços de saúde e de saneamento durante o período, observando os conflitos políticos ocorridos no processo e identificando as medidas tomadas pelas autoridades sanitárias durante e após a epidemia. Trata-se de um estudo interdisciplinar, que busca a compreensão mais aprofundada e abrangente dos problemas de saúde pública. A investigação foi baseada na análise de conteúdo de documentos da imprensa e institucionais e entrevistas. Segundo dados oficiais, a causa da epidemia foi a contaminação de um dos reservatórios de água que abastecem a cidade. A pesquisa mostrou que fatores de ordem política e social, como a instabilidade partidária e o nível de dependência política da sociedade local, contribuíram para a ocorrência do surto e para as dificuldades enfrentadas pelos agentes de saúde no decorrer da crise.In 2002, due to a toxoplasmosis epidemic Santa Isabel do Ivaí, Paraná State, was the focus of sanitary investigations. Four hundred and twenty six individuals had serology suggestive of acute T. gondii infection (IgM reactor, considered the largest outbreak of toxoplasmosis ever reported in the world. This research was meant to identify actions carried out by the sanitation and health services sector at that time, highlighting the political conflicts that took place during the process and identifying the measures taken by the sanitary authorities during and after the epidemic period. This is an interdisciplinary study aimed at understanding major problems of public health like this one. The investigation

  3. Metodologia comparada e análise da cobertura da corrupção política [Entrevista com Isabel Ferin Cunha

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    Fernanda Castilho

    2016-10-01

    Full Text Available A Prof.ª Dr.ª Isabel Ferin Cunha possui uma relação extremamente próxima com o Brasil desde os anos 1980, quando cursou mestrado e doutorado na Escola de Comunicações e Artes da Universidade de São Paulo (ECA-USP. Em virtude dessa relação privilegiada não apenas como o Brasil, mas como o espaço lusófono, na Universidade de Coimbra (Portugal, onde leciona no Departamento de Filosofia, Comunicação e Informação da Faculdade de Letras (FLUC, a docente orienta grande parte dos estudantes estrangeiros de língua portuguesa. O projeto “Corrupção política nos media: uma perspetiva comparada”, que atualmente coordena, financiado pela agência portuguesa de fomento FCT (Fundação para Ciência e Tecnologia, tem como objetivo analisar a cobertura jornalística da corrupção tanto na imprensa, como na televisão, para além da internet (blogs políticos, em três países: Portugal, Brasil e Moçambique. Nessa entrevista, Isabel Ferin aponta as dificuldades inerentes à realização de pesquisas comparadas, indicando caminhos para transpor questões como a utilização de metodologias comuns e análise de dados provenientes de diferentes realidades sociais e midiáticas. Por outro lado, afirma que o tratamento da corrupção política na mídia é um dos fatores da transformação da democracia no ocidente.

  4. Fluorose dentária em crianças de Princesa Isabel, Paraíba

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    FORTE Franklin Delano Soares

    2001-01-01

    Full Text Available Diversas localidades da Paraíba possuem níveis moderados ou elevados de fluoreto in natura nas águas de abastecimento. Nas áreas onde os níveis de fluoretos são considerados "ótimos" para a região (0,6 ppm, já constatou-se uma moderada prevalência de fluorose dentária (30-40%. O presente trabalho teve por objetivo observar a prevalência de fluorose dentária na cidade de Princesa Isabel, com níveis "subótimos" de fluoretos (0,4 ppm. Foram selecionados aleatoriamente 142 escolares de 10 a 15 anos para o levantamento de fluorose dentária pelo índice TF (de Thylstrup e Fejerskov. Os exames foram realizados por três examinadores previamente calibrados, sob luz natural indireta e após escovação supervisionada e secagem dos elementos dentários. Cerca de 20% dos escolares examinados apresentaram fluorose dentária, sendo que 70% com TF 1 e outros 30% distribuídos em diversos graus (TF 2 a 5. Fluorose foi mais prevalente no sexo masculino e em dentes pré-molares. Embora a fluorose dentária observada esteja dentro dos níveis esperados para o teor de fluoretos (0,4 ppm, outras fontes sistêmicas de fluoretos devem ser controladas. A prevalência de fluorose dentária observada não é problema de saúde pública nesta localidade.

  5. Un retrato desconocido de Isabel la Católica

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    Flor, Pedro

    2013-03-01

    Full Text Available The reserves of the National Gallery, London, house a painting identified as Mary Magdalene, by an unknown master most likely of Franco-Flemish origin. The iconographical identification of the subject derives from the small jar that she holds. A more thorough study of the piece, however, leads us to raise the hypothesis that it is actually a portrait of Isabella the Catholic, based on comparisons with other representations of this queen, as well as on the jewellery she wears. In spite of the stylistic comparisons made with contemporary works, it is difficult to establish the artist with precision. Nevertheless, we propose Michel Sittow –or someone from his artistic circle– whose activity at the service of the Spanish crown is documented precisely towards the end of the 15th and beginning of the 16th century.Las reservas de la National Gallery de Londres albergan una pintura identificada como María Magdalena atribuida a un maestro desconocido de posible origen franco-flamenco. La identificación iconográfica del personaje se basa en el pequeño frasco que sujeta. Sin embargo, un análisis más detallado de la obra nos permite plantear la hipótesis de que se trate antes de un retrato de Isabel la Católica, no sólo por comparación con otros ejemplares iconográficos de la Reina, sino también por las joyas que ostenta. Partiendo de la comparación estilística con obras coevas resulta problemático determinar con precisión el autor de la pintura, pero es posible que se trate de Michel Sittow o alguien de su círculo de influencia, cuya actividad se conoce precisamente a finales del siglo XV y principios del XVI al servicio de la corona española.

  6. Variación de la recarga entre La Plata y Santa Isabel (provincias de Buenos Aires y La Pampa - Argentina) : Propuesta metodológica

    OpenAIRE

    Hernández, Mario Alberto; Giai, Santiago B.

    1996-01-01

    Se analiza la recarga potencial de aguas subterráneas sobre un perfil entre La Plata y Santa Isabel (Buenos Aires y La Pampa). El mismo tiene la particularidad de ser perpendicular a las isohietas, extendiéndose desde una zona húmeda lindante con el río de la Plata, hasta otra de fuerte aridez y continentalidad, unos 900 km al Oeste. Algunos de los factores influyentes en el monto de la recarga tienen el mismo valor en todo el perfil, alcanzando su intervención igual peso en todas las local...

  7. Participative restoration of the monument national Bosque de Piedra Isabel Rubio

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    Barbarita Mijans Moreno

    2013-06-01

    Full Text Available The work was carried out in four hectares of the «Monument National» Bosque Piedra Isabel Rubio, belonging to the Forest Company Macurije municipality Guane. Ecosystem that possesses national significance because it constitutes a valuable monumental example, it summarizes natural aspects as their calcareous formations of the Jurassic period, besides their intangible values associated to the rural traditions. The objective of the research is to propose a plan of action participative for the restoration of this ecosystem starting from the results obtained in diagnose participative. Among the used scientific methods, they are the research Action Participative and the participant observation, for the collection of information the interview was used in depth, and the meetings in groups. As important results the presence of a strong pressure antropic is obtained on the flora, fauna and rocks of the minimogotes, the introduction of exotic and invasive species, and soil erosion, in consequence the degradation of the ecosystem and loss of the biodiversity. Another significant result constituted it the scarce level of the actors' knowledge regarding the category of this forest and the administrative juridical regulations that govern it. The removed evidences of these communities show that the necessity to diminish the antropics actions and to elevate the sensibility regarding the conservation, they impose a demand of knowledge to satisfy by means of training actions with the participation of the local actors and instrumentation of the regulative apparatus.

  8. Desenvolvimento e estudos de estabilidade de cremes e géis contendo sementes e extratos do bagaço da uva Isabel (Vitis labrusca L.

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    JOãO RONALDO N. FERREIRA

    2010-12-01

    Full Text Available No cenário mundial, inúmeras indústrias de cosméticos buscam a inovação, utilizando-se de matérias-primas de origens diversificadas, principalmente oriundas de vegetais, representando uma alternativa de substituição de materiais sintéticos por naturais. Com esse intuito, no presente estudo, realizou-se o desenvolvimento e a avaliação da estabilidade de emulsões e géis contendo extratos e sementes do bagaço da uva Isabel (Vitis labrusca L., uma espécie de uva rica em compostos fenólicos e flavonoides com grande atividade antioxidante. Com isso, buscou-se evidenciar o período em que os produtos mantiveram suas propriedades físico-químicas, frente a variações climáticas forçadas em estudos acelerados, durante o período de armazenamento. Foram preparados cremes contendo 5 e 10% de extrato glicólico do bagaço da uva e géis contendo 10% de sementes trituradas, sendo acondicionados em condições ambientais distintas e avaliados, através de testes físico-químicos, no período de 60 dias. Durante esse período, não foram evidenciados sinais de instabilidade físico-química nos cremes analisados frente às condições testadas. No entanto, o gel apresentou leve alteração da cor e do odor, sugerindo a necessidade de estabilização físico-química de seus constituintes naturais com a adição de antioxidantes. Palavras-chave: Antioxidante. Esfoliante. Estabilidade. Uva Isabel. Vitis labrusca L. ABSTRACT Development and testing of the stability of creams and gels containing extracts of the pomace and seeds of Isabel grapes (Vitis labrusca L. Numerous cosmetic companies around the world seek innovation, using raw materials of various origins, mainly derived from plants, as natural alternatives to synthetic materials. With this in mind, this study was carried out to develop and test the stability of emulsions and gels, respectively containing extracts of pomace and seeds of Isabel grape (Vitis labrusca L., a

  9. Análisis morfológico y métrico de la dentición y metapodios del oso de Deninger (Ursus deningeri Von Reichenau de la Cueva Sta. Isabel de Ranero. Aminocronología (Valle de Carranza - Bizkaia - País Vasco

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    TORRES, T., NESTARES, T., COBO, R., ORTIZ, J.E., CANTERO, M.A., ORTIZ, J., VIDAL, R., PRIETO, J.O.

    2001-01-01

    Full Text Available Se realiza un análisis métrico y morfológico de la dentición y metapodios del material de Ursus deningeri excavado en la Cueva Santa Isabel en Ranero (Bizkaia. Los resultados obtenidos se comparan con los de otras poblaciones ibéricas de U. deningeri (La Lucia en Quintanilla, Cantabria ; Cueva Mayor (sima de los Huesos en Atapuerca, Burgos y Lezetxiki en Mondragón, Gipuzkoa y de Ursus speleaus (Eiros en Triacastela, Lugo ; La Lucía, La Pasada en Guriezo, Cantabria ; Lezetxiki, Arrikrutz en Oñati, Gipuzkoa ; Ekain en Deba, Gipuzkoa ; Troskaeta en Ataun, Gipuzkoa ; Coro Tracito, Tella-Sin, Huesca ; El Toll en Moia, Barcelona y el Reguerillo en Patones, Madrid. El análisis morfológico y métrico revela que las muestras de oso de Santa Isabel se agrupan bien con las de U. deningeri de La Lucia y de la Sima de los huesos, pero con caracteres ligeramente más evolucionados a los de esta última, existiendo una gran distancia métrica morfológica con las poblaciones de U. spelaeus. El análisis de la racemización del ácido del colágeno de la dentina de las poblaciones de oso de las cavernas de la Península Ibérica ha permitido establecer que los osos de la Cueva de Santa Isabel son sincrónimos, o tal vez, algo más antiguos que los de la Sima de los Huesos. La ligera discrepancia existente entre la bioestratigrafía deducida a partir de la morfología dental y la obtenida mediante análisis de la racemización del ácido aspártico, se podría explicar por diferencias en las condiciones tafonómicas del yacimiento y/o un inferior número de muestras para el yacimiento de Santa Isabel.

  10. Efeito da safra vitícola na composição da uva, do mosto e do vinho Isabel da Serra Gaúcha, Brasil

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    Rizzon Luiz Antenor

    2006-01-01

    Full Text Available Entre os fatores que interferem na composição e na qualidade do vinho, destaca-se a safra vitícola, com suas variações climáticas. Com este objetivo, avaliou-se o efeito das safras de 1999, 2000 e 2001 na composição da uva, do mosto e do vinho Isabel da Serra Gaúcha. Nesse sentido, foram selecionados vinte e dois produtores de uva Isabel de onze municípios dessa região. Por ocasião da maturação, para as avaliações da uva e do mosto e a elaboração das microvinificações, foram colhidos 60kg de uva de cada viticultor. A safra vitícola interferiu significativamente no peso do cacho e da baga, mas não alterou a relação peso da ráquis/peso do cacho. No mosto, observaram-se diferenças em todas as variáveis, exceto para a relação degreesBrix/acidez total. No vinho, teve efeito na maior parte das variáveis avaliadas, com exceção aos cátions K, Mn, Cu e Rb. Em geral, a safra de 1999 foi a melhor, pois apresentou parâmetros mais adequados de acidez total, extrato seco, extrato seco reduzido, alcalinidade das cinzas, taninos, antocianinas e glicerol, variáveis essas que determinam a estrutura e a cor dos vinhos, importantes fatores para sua qualidade.

  11. Resistência induzida em frutos de videira 'Isabel' (Vitis Labrusca e seus efeitos sobre a qualidade pós-colheita Induced resistance in fruits of 'Isabel' vine (Vitis labrusca and its effects on post-harvest quality

    Directory of Open Access Journals (Sweden)

    Kedma Maria Silva Pinto

    2013-03-01

    Full Text Available A indução de resistência tem sido apontada como alternativa sustentável para o manejo de doenças, mas pouco se sabe sobre a interferência de tais produtos na qualidade pós-colheita dos frutos. Assim, o presente trabalho tem por objetivo avaliar a produção e a maturação de frutos de videira 'Isabel' (Vitis labrusca, oriundos de plantas tratadas com elicitores de resistência, em Natuba-PB. Os experimentos foram realizados nos períodos de setembro de 2009 a janeiro de 2010 (safra 1 e de fevereiro a junho de 2010 (safra 2. Foram utilizados oito tratamentos (Testemunha; Fungicida (Metiram + Piraclostrobina; Fosfito de potássio; Agro-Mós®; Fungicida + Fosfito de potássio; Fungicida + Agro-Mós®; Fosfito de potássio + Agro-Mós® e Fungicida + Fosfito de potássio + Agro-Mós® e quatro repetições de 5 plantas. As aplicações foram realizadas a cada 10 dias, iniciando-se 20 dias após a poda, totalizando 12 aplicações. As coletas de frutos foram realizadas aos 45; 60;90 e 120 dias após a poda. As variáveis analisadas foram: massa dos cachos, comprimento e diâmetro dos cachos, rendimento de polpa, sólidos solúveis (SS, pH, acidez titulável (AT e relação SS/AT. O tratamento com fosfito de potássio promoveu o aumento de 24% no comprimento dos cachos, em relação à testemunha, na primeira safra. O rendimento de polpa e a relação SS/AT não foram influenciados pelos tratamentos, e o teor de sólidos solúveis foi influenciado positivamente pela aplicação de fosfito de potássio, com incrementos superiores a 60%, em ambas as safras avaliadas.Induction of resistance has been identified as a sustainable alternative for disease management, but little information is known about the interference of such products in the postharvest fruit. Thus, the present study aims to evaluate the production and ripening of grapes 'Isabel' (Vitis labrusca from plants treated with resistance elicitors in Natuba-PB, Brazil. The experiments

  12. Os retratos de Maria Isabel e Maria Francisca de Bragança, de Nicolas-Antoine Taunay

    Directory of Open Access Journals (Sweden)

    Elaine Dias

    2011-01-01

    Full Text Available Nicolas-Antoine Taunay, French landscape painter, produced also several portraits during his stay at the Rio de Janeiro Court. In this city, in 1816, he paints the queen Carlota Joaquina and all her daughters. In this group, two portraits have a very special way: the paintings still today catalogued as Maria Francisca and Maria Teresa, but probably being Maria Isabel and Maria Francisca de Assis - princesses that, in this year, left Brazil to marry the Spanish King Fernando VII, and his brother Carlos Maria Isidro de Bourbon. In this article, beyond to describe these portraits (and analyse the identities of the portrayed princesses, I analyse their functions in the Court society and the mains artists of this gender in Europe. I will discuss, as well, the hypothesis about the Taunay choices. In this sense, I will analyse the possible circulation of the typologies of portrait between Italy, Portugal, Spain and France, understanding these productions by Taunay and the functions occupied by these portraits in the political relations between Brazil and Europe.

  13. The Madrid Royal Schools of St. Elisabeth and Loreto according Constitutions of 1715 and 1718 Los Reales Colegios de Santa Isabel y Loreto de Madrid según sus constituciones de 1715 y 1718

    Directory of Open Access Journals (Sweden)

    Beatriz COMELLA GUTIÉRREZ

    2013-02-01

    Full Text Available The Madrid Royal Schools of Saint Elizabeth and Loreto were founded by Philip II at the end of 16th Century. Both institutions provided education for orphan girls. They still exist as Catholic coeducational schools granted by the Education Department. These two Schools were Royal Sponsorship belonging to Palace ecclesiastical jurisdiction. The Schools Constitutions sanctioned by Philip V have been preserved until now. Although these Schools have a parallel history, the mentioned Constitutions are completely different for each School. According to these Norms, the Madrid Royal Schools of Saint Elizabeth and Loreto have many differences between them.Los Reales Colegios de Santa Isabel y Loreto de Madrid para niñas huérfanas fueron fundados por Felipe II a finales del siglo XVI. Ambas instituciones siguen funcionando en la actualidad como centros educativos católicos mixtos y concertados. Los dos fueron patronatos reales pertenecientes a la jurisdicción eclesiástica de Palacio. Se han conservado las Constituciones de ambos aprobadas bajo el reinado de Felipe V. Aunque los Colegios tienen una historia paralela, la citada normativa es muy diferente para cada institución; según las Constituciones, Santa Isabel y Loreto tienen más aspectos diferenciadores que comunes.

  14. The ‘other’ side of history as depicted in Isabel Allende’s Of Love and Shadows

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    M. Wenzel

    1996-05-01

    Full Text Available The proceedings of the Truth and Reconciliation Commission in South Africa have once again foregrounded the trauma involved in reconstructing a past fraught with political and personal violence and have, at the same time, also illustrated the therapeutic quality of testimony. Literature has always played a vital role in the process of coming to terms with reality. As a woman within a postcolonial context, Isabel Allende bears witness to political oppression and gender discrimination in her novels. They serve as examples of testimonial literature which focus on the plight of women as marginalized citizens and represent a collective conscience in testimony to the atrocities of the past. This is accomplished through the interaction of her fictional characters with a recognizable historical context. In Of Love and Shadows, her female protagonist, Irene, asserts her individuality through writing/reporting which questions the validity of the male-oriented and so-called “objective” historical reportage. By creating disparate and complementary perspectives which accentuate the female/personal as well as the male/public aspects of experience, Allende proposes a recognition of the personal and the peripheral in the documentation of historical events; she underlines the validity of the “other” side of experience and history.

  15. Diseño de un programa educativo de preparación para la jubilación en jubilados (as de Santa Isabel de las Lajas

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    Dailys Suárez Iglesias

    2013-10-01

    Full Text Available Resumen Ante la problemática social que se plantea en torno al envejecimiento, la presente investigación se propuso diseñar la propuesta de un programa educativo de preparación para la jubilación dirigido a jubilados (as del municipio Santa Isabel de las Lajas, Cienfuegos, Cuba. Constó de dos etapas, una diagnóstica (enero del 2007 a junio del 2008 y otra de diseño (de junio de 2008 a enero del 2009; la primera tuvo diseño de investigación explicativo, transversal, retrospectivo, cuasiexperimental, participaron como muestra 164 jubilados y tres grupos nominales de actores sociales; se emplearon: encuestas, cuestionario, entrevistas, grupo nominal, diagrama Ishikawa, método de Ranqueo, la matriz DAFO; en la segunda se realizó un diseño de intervención, prospectivo. La metodología que se siguió fue la planificación estratégica, su validación fue por criterios de especialistas. Se identificaron los factores socioculturales, familiares e individuales influyentes en la adaptación a la jubilación y su repercusión psicológica, se constató que no existe en el municipio un programa de preparación para la jubilación, más de la mitad de los jubilados no están adaptados a la jubilación. Se diseñó un programa educativo de preparación para la jubilación, el cual cumple con los requisitos establecidos para su diseño y aplicabilidad. (DUAZARY 2010, 49 - 59AbstractFacing the present day situation in regard to persons getting old, the present investigation intended to design a proposal of a an educative program for the preparation of retirement directed to old person who want to retire in Santa Isabel de Las Lajas town, Cienfuegos, Cuba. The investigation had two phases. One devoted to make a diagnostic (January 2007 –June 2008 and the other devoted to design the educative program (June 2008—January 2008. The diagnostic, applied in San Isabel de Las Lajas, Cienfuegos, Cuba, consisted in identifying the factors which influence

  16. The effect of Isabel grape addition on the physicochemical, microbiological and sensory characteristics of probiotic goat milk yogurt.

    Science.gov (United States)

    Silva, Francyeli Araújo; de Oliveira, Maria Elieidy Gomes; de Figueirêdo, Rossana Maria Feitosa; Sampaio, Karoliny Brito; de Souza, Evandro Leite; de Oliveira, Carlos Eduardo Vasconcelos; Pintado, Maria Manuela Estevez; Ramos do Egypto Queiroga, Rita de Cássia

    2017-06-21

    Goat milk is an attractive food because of its nutritional properties, easy digestibility and hypoallergenicity. Goat milk yogurt is an appropriate matrix for the inclusion of new ingredients such as probiotic cultures, fruit and its derivatives. Grapes are rich in polyphenols and recognized for their health benefits. The aim of this study was to improve the quality characteristics of probiotic goat milk yogurt by the addition of an Isabel grape (Vitis labrusca L.) preparation (IGP). For this, the influence of the addition of IGP on the physicochemical, microbiological and sensory characteristics of goat milk yogurt containing the probiotic Lactobacillus acidophilus LA-05 was evaluated during 28 days of refrigerated storage (5 ± 0.5 °C). Four yogurt formulations were prepared, each varying in the added IGP amount, as follows: Y0 (not containing IGP), YG15 (containing 15 g per 100 mL of IGP), YG20 (containing 20 g per 100 mL of IGP), and YG25 (containing 25 g per 100 mL of IGP). All formulations showed probiotic counts ranging from 7 to 8 log CFU mL -1 over the assessed storage period. The addition of 20 g per 100 mL of IGP affected positively the colour, viscosity, and sensory acceptance of the yogurt formulations. The production of goat milk yogurt containing L. acidophilus LA-05 and IGP is an option for developing a new goat dairy product with added value due to the inclusion of components with potential functional properties.

  17. Grapevine yield components and composition of Isabel grape produced according to the organic and conventional systems

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    Miele Alberto

    2016-01-01

    Full Text Available There is an increasing demand for organic grapes by the juice industry of Serra Gaúcha, Brazil. This region presents a humid and hot summer, ideal climatic conditions for the development of a number of diseases. To control such diseases and problems brought about by other organisms, growers apply pesticides on the grapevines which may leave residues in grapes. However, in general, grapes produced by organic system have lower yield, but there is a lack of research data on this subject. Thus, an experiment was carried out over three years in order to compare the yield components and the physicochemical composition of the must of Isabel grapes conducted in both production systems. When the grapes were ripe, variables related to yield components were evaluated, such as the number of clusters/vine, yield/vine and weight/cluster. Then the grapes were sampled and taken to the laboratory where they were crushed and the musts were centrifuged and analyzed. The 3-year data mean were submitted to correlation analysis and Principal Component Analysis. The results show that conventional grapevines produced 2.18 times more than organic. However, the grapes from the organic system had higher density, Brix, pH, Brix/titratable acidity ratio, P and Mg but lower K, and Ca varied little between both production systems.

  18. Las sociedades musicales en el Madrid de Isabel II (1833-1868

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    Diez Huerga, M. Aurelia

    2003-12-01

    Full Text Available After the fall of the monarchist absolutism, the middle class, whom the economic liberalism gives an unprecedented strength, demands new entertainments, new places to make profitable social relationships and, definitely, new ways to show their influence and power. On the other hand, the shift of political rules allows people to express and gather, even if with some restrictions, and opens the door to the progressive democratization of society, with its cultural consequences. That ensemble of factors leads to the appearance of many different institutions but with a constant feature: the defence of the liberal ideas, the good fellowship and communication among individuals (which includes the recreational side, the cultural divulging and artistic expression. It is at this point that establishments with both musical and educational activity must be taken into account. This essay intends to go through organizations such as Liceo Artístico y Literario, Instituto Español, La Unión, Museo Lírico, El Genio and many other artistic societies which proliferated during the 1830s and 1840s, centres with an intense social and musical activity in Madrid during Isabel II's era. Their influence in this area must be underlined, as devoted to promote performance, composition and, which is highly important, music instruction. The selected society of Madrid could be found there, gathered to learn music rudiments, singing and playing as well as to listen to the repertory in vogue at that time and to take part itself in its performance.

    Tras la caída del absolutismo monárquico, la burguesía, a quien el liberalismo económico dota de una pujanza sin precedentes, demanda nuevos entretenimientos, nuevos espacios para granjearse relaciones sociales convenientes y, en definitiva, nuevas formas para ostentar su influencia y poder. Por otra parte, el cambio de régimen político abre las puertas a las libertades de expresión y de reunión, aunque sea con

  19. Hindcasting of Storm Surges, Currents, and Waves at Lower Delaware Bay during Hurricane Isabel

    Science.gov (United States)

    Salehi, M.

    2017-12-01

    Hurricanes are a major threat to coastal communities and infrastructures including nuclear power plants located in low-lying coastal zones. In response, their sensitive elements should be protected by smart design to withstand against drastic impact of such natural phenomena. Accurate and reliable estimate of hurricane attributes is the first step to that effort. Numerical models have extensively grown over the past few years and are effective tools in modeling large scale natural events such as hurricane. The impact of low probability hurricanes on the lower Delaware Bay is investigated using dynamically coupled meteorological, hydrodynamic, and wave components of Delft3D software. Efforts are made to significantly reduce the computational overburden of performing such analysis for the industry, yet keeping the same level of accuracy at the area of study (AOS). The model is comprised of overall and nested domains. The overall model domain includes portion of Atlantic Ocean, Delaware, and Chesapeake bays. The nested model domain includes Delaware Bay, its floodplain, and portion of the continental shelf. This study is portion of a larger modeling effort to study the impact of low probability hurricanes on sensitive infrastructures located at the coastal zones prone to hurricane activity. The AOS is located on the east bank of Delaware Bay almost 16 miles upstream of its mouth. Model generated wind speed, significant wave height, water surface elevation, and current are calibrated for hurricane Isabel (2003). The model calibration results agreed reasonably well with field observations. Furthermore, sensitivity of surge and wave responses to various hurricane parameters was tested. In line with findings from other researchers, accuracy of wind field played a major role in hindcasting the hurricane attributes.

  20. Incidencias del uso de las NTIC en las formas de aprendizaje de los estudiantes de la Escuela del Milenio Mejía D7 vs. la Escuela Fiscal Isabel Ruilova Calahorrano: 2015-2016

    OpenAIRE

    Salazar Cando, Martha Patricia

    2017-01-01

    El propósito de esta investigación fue analizar las incidencias del uso de las NTIC en las formas de aprendizaje de los estudiantes de la Escuela del Milenio Mejía D7 vs. La Escuela Fiscal Isabel Ruilova Calahorrano: 2015 -2016, las dos instituciones pertenecen al sistema fiscal, con la diferencia que la unidad del milenio tiene tecnología de punta, en cambio la escuela fiscal no dispone de tecnología, esto permitió establecer un estudio en las formas de aprender con el uso de las NTIC y sin ...

  1. Relación entre el clima social familiar y la autoestima de los estudiantes del cuarto grado de educación secundaria de la I.E. Isabel Chimpu Ocllo del distrito de San Martín de Porres - Lima

    OpenAIRE

    Pejerrey Campodónico, Rubeni

    2015-01-01

    El presente trabajo se originó gracias a la convivencia diaria con los estudiantes de la IE Isabel Chimpu Ocllo en la que surge la necesidad por determinar la relación entre el clima social familiar y la autoestima de los estudiantes, toda vez que merecen ser comprendidos y orientados adecuadamente ante cuestiones evidentes donde los adolescentes en su mayoría manifiestan actitudes impacientes, violentas e irrespetan las normas de convivencia. El trinomio de la educación: estudiantes, padres ...

  2. Prevalencia y grado de pie plano según estado nutricional en niños escolares de las instituciones educativas Santa Isabel de Hungría y Santa Teresita de Jesús. Casma. 2010

    OpenAIRE

    Sánchez Reyna, Luis Fernando

    2016-01-01

    El objetivo del estudio fue establecer la prevalencia y grado de pie plano en relación al estado nutricional en niños escolares matriculados en las Instituciones Educativas Santa Isabel de Hungría y Santa Teresita de Jesús de la ciudad de Casma. Este estudio cuantitativo, descriptivo y transversal evaluó a 321 niños escolares durante el año 2010. Se clasificó en niños eutróficos, con sobrepeso y obesidad según las tablas del IMC para la edad de la OMS, y en niños con pie normal o pie plano de...

  3. Estratégias de leitura e competência leitora: contribuições para a prática de ensino em História Reading strategies and reading comprehension: contributions to the teaching of History

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    Vitória Rodrigues e Silva

    2004-01-01

    Full Text Available Este artigo tem por objetivo tecer algumas considerações sobre as contribuições que a metodologia de leitura apresentada por Isabel Sole pode oferecer para a prática do ensino de História. O aprimoramento da competência leitora, papel central da escola, deve ser preocupação permanente dos professores dessa disciplina, contribuindo desse modo para a melhoria do desempenho dos alunos do Ensino Básico.This article intends to discuss about the benefits of the reading strategies to the teaching of History, showed by Isabel Solé, in order to improve the development of the students' reading comprehension and, this way, improve their school learning perfomance.

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. ISABEL HERRMANN. Articles written in Bulletin of Materials Science. Volume 41 Issue 1 February 2018 pp 18. Advanced nanofibrous textile-based dressing material for treating chronic wounds · ISABEL HERRMANN EKO SUPRIYANTO SARAVANA KUMAR JAGANATHAN A ...

  5. Archive of post-Hurricane Isabel coastal oblique aerial photographs collected during U.S. Geological Survey Field Activity 03CCH01 from Ocean City, Maryland, to Fort Caswell, North Carolina and Inland from Waynesboro to Redwood, Virginia, September 21 - 23, 2003

    Science.gov (United States)

    Subino, Janice A.; Morgan, Karen L.M.; Krohn, M. Dennis; Dadisman, Shawn V.

    2013-01-01

    On September 21 - 23, 2003, the United States Geological Survey (USGS) conducted an oblique aerial photographic survey along the Atlantic coast from Ocean City, Md., to Fort Caswell, N.C., and inland oblique aerial photographic survey from Waynesboro to Redwood, Va., aboard a Navajo Piper twin-engine airplane. The coastal survey was conducted at an altitude of 500 feet (ft) and approximately 1,000 ft offshore. For the inland photos, the aircraft tried to stay approximately 500 ft above the terrain. These coastal photos were used to document coastal changes like beach erosion and overwash caused by Hurricane Isabel, while the inland photos looked for potential landslides caused by heavy rains. The photos may also be used as baseline data for future coastal change analysis. The USGS and the National Aeronautics and Space Administration (NASA) surveyed the impact zone of Hurricane Isabel to better understand the changes in vulnerability of the Nation’s coasts to extreme storms (Morgan, 2009). This report serves as an archive of photographs collected during the September 21 - 23, 2003, post-Hurricane Isabel coastal and inland oblique aerial survey along with associated survey maps, KML files, navigation files, digital Field Activity Collection System (FACS) logs, and Federal Geographic Data Committee (FGDC) metadata. Refer to the Acronyms page for expansions of all acronyms and abbreviations used in this report. The USGS St. Petersburg Coastal and Marine Science Center (SPCMSC) assigns a unique identifier to each cruise or field activity. For example, 03CCH01 tells us the data were collected in 2003 for the Coastal Change Hazards (CCH) study and the data were collected during the first field activity for that project in that calendar year. Refer to http://walrus.wr.usgs.gov/infobank/programs/html/definition/activity.html for a detailed description of the method used to assign the ID number. The photographs provided here are Joint Photographic Experts Group (JPEG

  6. ROOTSTOCKS EFFECTS ON THE PHYSICOCHEMICAL CHARACTERISTICS OF BORDÔ, ISABEL AND IAC 138-22 MÁXIMO MUST AND WINE

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    MARLON JOCIMAR RODRIGUES DA SILVA

    2017-09-01

    Full Text Available ABSTRACT It has been demonstrated that rootstocks can influence grape characteristics, but there are few data in literature about the rootstocks influence in the wine characteristics, especially in wines elaborated with Vitis labrusca or hybrid grapes. This study evaluated the influence of ‘IAC 766’ and ‘106-8 Mgt’ rootstocks on the physicochemical characteristics of ‘Bordô’, ‘Isabel’ and ‘IAC 138-22 ‘Máximo’ musts and wines. The musts were evaluated for pH, soluble solids, total acidity and soluble solids/acidity ratio. The wines were evaluated for density, alcohol content; total, volatile and fixed acidity; pH, dry extract, reducing sugars, reduced dry extract, alcohol in weight/reduced dry extract; free and total sulfur dioxide; anthocyanins, polyphenols index (I 280; polyphenols and total flavonoids and antioxidant activity. The ‘Bordô’, ‘Isabel’ and IAC 138-22 ‘Máximo’ musts had low soluble solids for winemaking. The ‘106-8 Mgt’ rootstock promoted higher dry extract content and reduced dry extract in Bordô wine, and lower total and fixed acidity in IAC 138-22 Máximo wine. In Isabel wine, higher pH was promoted by the ‘IAC 766’ rootstock. Aside from low total acidity of the Bordô wine, all the physicochemical characteristics of the wines studied are in accordance with Brazilian law. There was no effect of rootstocks in the phenolics content and antioxidant activity of wines.

  7. 1 Isabel Allende: Carnalismo and Female Identity

    African Journals Online (AJOL)

    2015-04-27

    Apr 27, 2015 ... the strange, the uncanny, the eerie and the dreamlike – but not the fantastic – aspects of ... search for those things, a search for spirituality, for nature, for the .... She put her papers in order, and salvaged her notebooks that.

  8. Isabel la Católica y el marqués de Cádiz, o la cortesía en la representación historiográfica del poder

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    Juan Luis CARRIAZO RUBIO

    2006-03-01

    Full Text Available On analyse ici la reconstruction, dans les chroniques, du processus complexe de soumission de la maison d’Arcos à la nouvelle monarchie qu’incarne la reine Isabelle. La présence d’une femme sur le trône de Castille fut, pour les chroniqueurs, l’occasion de condenser dans une série de scènes d’une grande intensité littéraire, le rapprochement compliqué, non sans négociations, qui fit de Rodrigo Ponce de León, l’adversaire redouté, un héros, voire une icône du projet politique des Rois Catholiques. Palencia, Valera, Pulgar ou encore Bernáldez, entre autres, proposent des versions parfois divergentes où ils attribuent, moyennant quelques écarts sensibles, un rôle plus ou moins important à Isabelle dans sa réconciliation avec le marquis. Mais au-delà des intérêts et des marques de loyauté des chroniqueurs, la présence même de la reine est un moyen de compléter le profil guerrier de ce héros de la frontière par l’évocation de manifestations de courtoisie des plus raffinées.Se analiza aquí la plasmación cronística del complejo proceso de sumisión de la Casa de Arcos a la nueva monarquía encarnada por la reina Isabel. No en vano, la presencia de una mujer en el trono de Castilla brindó a los cronistas la posibilidad de condensar en una serie de escenas de gran intensidad literaria el complicado acercamiento, no exento de negociaciones, que transformó a Rodrigo Ponce de León de adversario temido en héroe e incluso icono del proyecto político de los Reyes Católicos. Palencia, Valera, Pulgar o Bernáldez, entre otros, ofrecen relatos no siempre coincidentes que divergen de manera sensible al conceder a Isabel mayor o menor protagonismo en la reconciliación con el marqués. Pero más allá de los intereses y lealtades de los cronistas, la propia presencia de la reina les permite completar el perfil guerrero del héroe fronterizo con las más refinadas manifestaciones de cortesía.

  9. Bioactive compounds and juice quality from selected grape cultivars

    Directory of Open Access Journals (Sweden)

    Renata Vieira da Mota

    2017-12-01

    Full Text Available ABSTRACT Grape juices have been valued due to their potential health benefits, which have demanded increased grape productivity and quality. Five grape cultivars grown in Brazil, Isabel Precoce, Carmem, Violeta, Concord and Bordo were evaluated in 2013 and 2014 seasons for bioactive components and also for juice processing quality traits. Production cycle was the longest for Carmem but lower and similar for Violeta, Isabel, Bordo and Concord. Isabel showed higher productivity (5.4 kg∙plant-1 but lowest soluble solids content (16.9 °Brix, anthocyanins (26.7 mg∙100 g-1 and total phenolics (110.7 mg∙100 g-1. The highest anthocyanins contents were observed in Violeta (189.9 mg∙100 g-1 and Bordo (133.8 mg∙100 g-1. These cultivars were also rich in phenolics (356.1 and 239.5 mg∙100 g-1, respectively. The highest anthocyanin and total phenolics concentrations were found in Violeta juice (2.68 and 6.33 g∙L-1 followed by Bordo (1.44 and 2.86 g∙L-1. Isabel juice had the lowest content, 0.14 and 1.29 g∙L-1, respectively. Biogenic amines were found at low concentrations only in the juices. Putrescine and spermidine were the major amines detected in juices. Phenylethylamine was detected only in Bordo juice from 2013 season and tryptamine was detected only in 2014 season. Blends were preferred over varietal juices except for Carmem.

  10. Mujeres detrás de la escena: Isabel Carrasquilla y Sofía Ospina de Navarro, dramaturgas al margen en la primera mitad del siglo XX en Colombia

    Directory of Open Access Journals (Sweden)

    Nancy Johana Correa Serna

    2018-01-01

    Full Text Available El artículo analiza las representaciones de género de tres comedias de Isabel Carrasquilla de Arango y dos de Sofía Ospina de Navarro, quienes son consideradas como intelectuales; productoras de representaciones y de discursos. Aunque su destacada posición social les permitió intervenir en la escena pública de Medellín, dominada por esquemas masculinos, en parte como un legado de ese poder letrado del siglo XIX, estuvieron al margen, pues no contaron con educación superior y, dentro de la escena cultural, su actividad intelectual se asoció generalmente a las figuras masculinas que las rodearon durante sus vidas. Así mismo, sus producciones fueron identificadas con los denominados géneros menores: crónica, cuento y pequeñas obras teatrales, que se consideraban aceptables y propicias para las mujeres. Sin embargo, sus comedias presentan una visión renovada, y a veces transgredida, sobre los estereotipos de género de la época.

  11. Neuronal Rac1 Is Required for Learning-Evoked Neurogenesis

    Science.gov (United States)

    Anderson, Matthew P.; Freewoman, Julia; Cord, Branden; Babu, Harish; Brakebusch, Cord

    2013-01-01

    Hippocampus-dependent learning and memory relies on synaptic plasticity as well as network adaptations provided by the addition of adult-born neurons. We have previously shown that activity-induced intracellular signaling through the Rho family small GTPase Rac1 is necessary in forebrain projection neurons for normal synaptic plasticity in vivo, and here we show that selective loss of neuronal Rac1 also impairs the learning-evoked increase in neurogenesis in the adult mouse hippocampus. Earlier work has indicated that experience elevates the abundance of adult-born neurons in the hippocampus primarily by enhancing the survival of neurons produced just before the learning event. Loss of Rac1 in mature projection neurons did reduce learning-evoked neurogenesis but, contrary to our expectations, these effects were not mediated by altering the survival of young neurons in the hippocampus. Instead, loss of neuronal Rac1 activation selectively impaired a learning-evoked increase in the proliferation and accumulation of neural precursors generated during the learning event itself. This indicates that experience-induced alterations in neurogenesis can be mechanistically resolved into two effects: (1) the well documented but Rac1-independent signaling cascade that enhances the survival of young postmitotic neurons; and (2) a previously unrecognized Rac1-dependent signaling cascade that stimulates the proliferative production and retention of new neurons generated during learning itself. PMID:23884931

  12. Learning, Play, and Your 1- to 3-Month-Old

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Learning, Play, and Your 1- to 3-Month-Old ... Baby to Learn Print What Your Baby Is Learning After learning to recognize your voice, your face, ...

  13. Effects of cold stratification, sulphuric acid, submersion in hot and ...

    African Journals Online (AJOL)

    Effects of cold stratification, sulphuric acid, submersion in hot and tap water pretreatments in the greenhouse and open field conditions on germination of bladder-Senna ( Colutea armena Boiss. and Huet.) seeds.

  14. Step 1: Learn about Diabetes

    Science.gov (United States)

    ... please turn JavaScript on. Feature: Type 2 Diabetes Step 1: Learn About Diabetes Past Issues / Fall 2014 ... the whole family healthy! Here are four key steps to help you control your diabetes and live ...

  15. Sounding the alarm on chronic kidney disease in farming communities: María Isabel Rodríguez MD. Minister of health, El Salvador. Interview by Conner Gorry.

    Science.gov (United States)

    Rodríguez, María Isabel

    2013-07-01

    In April 2013, a consortium of regional health ministries, nongovernmental organizations, aid agencies, clinical specialists and researchers from diverse sectors convened in San Salvador to discuss the epidemic of chronic kidney disease of unknown or non-traditional causes (CKDu) plaguing agricultural communities in Central America and beyond. The three-day meeting, where presentation of research on the clinical and epidemiological characteristics of CKDu roused significant debate, led the Pan American Health Organization to declare CKDu "a pressing and serious health problem [which] represents a burden for families, communities, health systems and society as a whole."[1] This High-level Meeting on Chronic Kidney Disease of Non-Traditional Causes in Central America (24-26 April) followed several international meetings at which Dr María Isabel Rodríguez, El Salvador's Minister of Health, presented studies on the disease burden in her country, where end-stage renal disease is the leading cause of hospital deaths. She outlined results of original scientific research by Dr Carlos Orantes (first published in MEDICC Review), that described an "elevated prevalence of chronic kidney disease, chronic renal failure and risk factors" among the patients studied, noting that "the most common [form] was chronic kidney disease of unknown cause, associated with neither diabetes nor hypertension."[2] In this interview with MEDICC Review, Dr Rodríguez discussed the gravity of the problem in Salvadoran agricultural communities; the importance of CKDu research in other countries; and the urgent need for intersectoral action and active community participation to confront and control the epidemic.

  16. Significación y trascendencia del género epistolar en la política cortesana: la correspondencia inédita entre la Infanta Isabel Clara Eugenia y el Marqués de Velada

    Directory of Open Access Journals (Sweden)

    Santiago Martínez Hernández

    2004-08-01

    Full Text Available The aim of this paper is make known the unpublished correspondence maintained between the Infanta Isabel Clara Eugenia and the Marquis of Velada, her lord high steward for a period of eleven years in the early seventeenth century. This private correspondence has become a vital source of information, especially for the historiography of the court, specifically in comparison with official correspondence. The content of the letters brings nuance and personal judgements which, by virtue of the freedom with which they were written, prove to have a much greater value than the public documents. Certainly, the letters not only transmitted news but also became a powerful means for maintaining the relationship over a considerable distance. This correspondence provides a number of insights into the political and personal relations between a princess and a courtier. The article also includes a transcription and abstract of the letters.

  17. A importância da educação ambiental no processo de construção e execução de projeto político pedagógico em escolas municipais de Princesa Isabel – PB

    Directory of Open Access Journals (Sweden)

    Elayne Bernardino de Sousa

    2015-06-01

    Full Text Available A preocupação com a Educação Ambiental (EA tem incentivado diversos estudiosos de diferentes áreas a contemplarem esse tema e a desenvolverem novas perspectivas sobre ele. Muitos autores a relacionava somente com a preservação e ações conservacionistas do meio ambiente, mas sua dimensão vai além, a exemplo da própria interação entre os sujeitos como uma dessas propostas. Nesse sentido, este artigo é resultado de um projeto do programa de Iniciação Cientifica e Tecnológica (PIBICT. O objetivo deste trabalho é identificar a importância da EA no processo de construção e execução do Projeto Político Pedagógico (PPP nas escolas municipais de Princesa Isabel – PB. A metodologia se fez por meio de entrevistas e aplicação de questionários, além de análise documental do PPP existente, do regimento escolar, do plano de desenvolvimento da escola, do projeto Selo Verde na Escola: pensar, sentir e agir e do Projeto COM-VIDA. Ademais, as observações/conversas informais durante os contatos com a escola e seus atores sociais também foram valorizadas. Os resultados da pesquisa mostraram que as escolas municipais urbanas de Princesa Isabel ainda estão atreladas a uma visão reducionista da temática ambiental, pois não conseguem, ainda, identificar a EA como um processo amplo, em que a relação sociedade/natureza está presente, tendo muitas vezes a percepção de conscientização à preservação ao meio ambiente, mas não priorizam as interações entre os sujeitos e destes com o meio por meio de atividades cotidianas.

  18. 26 CFR 1.25A-4 - Lifetime Learning Credit.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Lifetime Learning Credit. 1.25A-4 Section 1.25A-4... Rates During A Taxable Year § 1.25A-4 Lifetime Learning Credit. (a) Amount of the credit—(1) Taxable years beginning before January 1, 2003. Subject to the phaseout of the education tax credit described in...

  19. English Orthographic Learning in Chinese-L1 Young EFL Beginners.

    Science.gov (United States)

    Cheng, Yu-Lin

    2017-12-01

    English orthographic learning, among Chinese-L1 children who were beginning to learn English as a foreign language, was documented when: (1) only visual memory was at their disposal, (2) visual memory and either some letter-sound knowledge or some semantic information was available, and (3) visual memory, some letter-sound knowledge and some semantic information were all available. When only visual memory was available, orthographic learning (measured via an orthographic choice test) was meagre. Orthographic learning was significant when either semantic information or letter-sound knowledge supplemented visual memory, with letter-sound knowledge generating greater significance. Although the results suggest that letter-sound knowledge plays a more important role than semantic information, letter-sound knowledge alone does not suffice to achieve perfect orthographic learning, as orthographic learning was greatest when letter-sound knowledge and semantic information were both available. The present findings are congruent with a view that the orthography of a foreign language drives its orthographic learning more than L1 orthographic learning experience, thus extending Share's (Cognition 55:151-218, 1995) self-teaching hypothesis to include non-alphabetic L1 children's orthographic learning of an alphabetic foreign language. The little letter-sound knowledge development observed in the experiment-I control group indicates that very little letter-sound knowledge develops in the absence of dedicated letter-sound training. Given the important role of letter-sound knowledge in English orthographic learning, dedicated letter-sound instruction is highly recommended.

  20. Among Paulas, Martas, Pedros, Anas... in order to understand the complex subjects/knowledge relations in the context of historical learning

    Directory of Open Access Journals (Sweden)

    Flávia Eloisa Caimi

    2013-12-01

    Full Text Available We comprehend the learning room as a space where teachers and students knowledge cross it other, permeated by the idiosyncrasies from the society that surrounds the school. This study aims know the pedagogical practice of two teachers in the history teaching for the formers years of the fundamental school, to comprehend as the work that they develop interfere in the student’s historical knowledge construction. The study of case method of survey had the contribution of the teachers of two municipal schools from Londrina. The data, collected through the observation inside the learning room and semi structured interviews with the teachers, were analyzed from the theoretical assumptions announced by Isabel Barca, Hilary Cooper and Keity Barton. We concluded that there are similarities and differences on the teacher’s practice and the students behavior in both classrooms. From a general view, the work with the history is based, nearly exclusively, in the didactical book reading and in the demand to the students retain the information from it. There’s a silence in front of the questions raised by the students about the content and the mechanisms that permit the students to comprehend that the past can have many interpretations are inexistent.

  1. Effects of changing irrigation practices on the ground-water hydrology of the Santa Isabel-Juana Diaz area, south central Puerto Rico

    Science.gov (United States)

    Ramos-Gines, Orlando

    1994-01-01

    Prior to 1930, the principal source of water for irrigation in the Santa Isabel-Juana Diaz area was surface water from outside the study area, which was delivered by a complex channel-pond system. Recharge from water applied to the fields, estimated to be 18.7 million of gallons per day, and discharge by ground-water flow to sea, estimated to be 17 million of gallons per day, were the major water- budget components prior to intensive development of the ground-water resources. Development of the ground-water resources after 1930 resulted in a substantial increase in irrigation, primarily furrow irrigation. The surface water supplied by the complex channel-pond system continued to be used and ground-water withdrawals increased sub- stantially. By 1966-68, ground-water recharge from irrigation water applied to the fields, estimated to be 37 million of gallons per day, and discharge by pumpage for irrigation, estimated to be 77 million of gallons per day, were the two major components of the ground-water budget. By 1987, drip irrigation had become the principal method of irrigation in the study area, and surface-water irrigation had, for the most part, been discontinued. The estimated aquifer recharge from irrigation water in 1987 was about 6.6 million of gallons per day, which occurred primarily in the remaining fields where furrow irrigation was still practiced. Although aquifer recharge had been reduced as a result of the conversion from furrow to drip irrigation, water levels in the aquifer were higher in 1987 than in 1968 because of the large reduction in ground-water withdrawals and subsequent recovery of ground-water levels.

  2. Negative Transfer of L1 on English Grammar Learning in SLA

    Institute of Scientific and Technical Information of China (English)

    马秀琳

    2015-01-01

    At present,many scholars pay more attention to the positive transfer of native language on the English learning,while ignoring the negative transfer of L1 on English grammar learning.Therefore native transfer of L1 often appears on English grammar learning.This paper aims to point out that the negative transfer of L1 has a profound and vast influence on the English grammar learning,to find out the countermeasures to reduce the influence of negative transfer of L1 and finally to bring the benefits to the following relative studies.

  3. PENGEMBANGAN PORTAL E-LEARNING SMK NEGERI 1 MANGGIS

    Directory of Open Access Journals (Sweden)

    Luh Joni Erawati Dewi

    2013-08-01

    Full Text Available Portal E-learning SMK Negeri 1 Manggis adalah sebuah sistem yang dibuat untuk membantu serta mendukung proses pembelajaran baik pemberian materi maupun tugas secara online. Dengan adanya portal e-learning ini diharapkan dapat meningkatkan kadar interaksi pembelajaran antara peserta didik dengan guru karena memungkinkan terjadinya interaksi pembelajaran dari mana dan kapan saja. Selain itu, melatih siswa lebih mandiri dan aktif dalam mendapatkan ilmu pengetahuan, serta mempermudah penyimpanan materi pembelajaran. Perancangan sistem ini digambarkan dengan menggunakan DFD (data flow diagram dan diimplementasikan dengan menggunakan Adobe Dreamwaver sebagai editor, Adobe Photoshop  sebagi pengelola design, PHP sebagai script programing, dan MYSQL sebagai pengolah basis data.   Kata-kata kunci: portal, e-learning, SMK Negeri 1 Manggis

  4. A Functional Genomic Analysis of NF1-Associated Learning Disabilities

    National Research Council Canada - National Science Library

    Tang, Shao-Jun

    2008-01-01

    Learning disabilities severely deteriorate the life of many NF1 patients. However, the pathogenic process for NF1-associated learning disabilities has not been fully understood and an effective therapy is not available...

  5. A Functional Genomic Analysis of NF1-Associated Learning Disabilities

    National Research Council Canada - National Science Library

    Tang, Shao-Jun

    2007-01-01

    Learning disabilities severely deteriorate the life of many NF1 patients. However, the pathogenic process for NF1-associated learning disabilities has not been fully understood and an effective therapy is not available...

  6. Influência do dióxido de enxofre e cultivares de videira na formação de alguns compostos voláteis e na qualidade sensorial do destilado de vinho Influence of sulfur dioxide and grape varieties at the formation of some volatile compounds and at the sensory quality of the wine distillate

    Directory of Open Access Journals (Sweden)

    Marco Antonio SALTON

    2000-12-01

    Full Text Available Com o objetivo de estudar o efeito do SO2 e das cultivares de videira - Herbemont, Couderc 13, Trebbiano e Isabel - na composição química e na qualidade sensorial do destilado de vinho, efetuaram-se microvinificações e posterior destilação dos vinhos na safra de 1996. As análises dos compostos voláteis foram feitas através de cromatografia gasosa e a avaliação sensorial dos destilados foi efetuada pelo grupo de degustação da Embrapa Uva e Vinho. Os resultados mostraram que o SO2 favoreceu a formação de etanal nas cultivares estudadas. Observou-se também um aumento na soma dos álcoois superiores em função do SO2, exceto para o destilado da cv. Isabel. Constatou-se que o destilado de Isabel se caracterizou por apresentar teor mais elevado de metanol e mais baixo de 1-propanol, possivelmente devido ao sistema de vinificação. O destilado de Isabel, juntamente com o de Couderc 13, apresentou teores mais baixos de 2-metil-1-propanol, 3-metil-1-butanol e da soma dos álcoois superiores. O destilado de Trebbiano apresentou teor mais elevado de 2-metil-1-propanol e juntamente com o de Herbemont teores mais elevados de 1-propanol, 2-metil-1-butanol, 3-metil-1-butanol e na soma dos álcoois superiores. A avaliação sensorial evidenciou que o SO2 influenciou na qualidade de aroma, no gosto agradável e na qualidade geral dos destilados das cultivares Herbemont e Trebbiano. O de Herbemont se caracterizou por apresentar menor qualidade de aroma, gosto agradável, tipicidade e qualidade geral. Apresentou, ainda, nota mais elevada para aroma e gosto indesejáveis.With the aim of studying the influence of SO2 and grape varieties - Herbemont, Couderc 13, Trebbiano and Isabella, on the chemical composition and sensory quality of wine distillates, some microvinification and posterior distillation of wines were made, at the harvest of 1996. The analyses of volatile components were made through gas chromatography and the sensory evaluation of

  7. The Literal and the Literary: A Note on the Historical References in Isabel Allende's La casa de los espíritus

    Directory of Open Access Journals (Sweden)

    Scott Macdonald Frame

    2003-06-01

    Full Text Available Stripped of much of its individuality as a piece of literature and relegated to the niche set aside for women's writing, Isabel Allende's La casa de los espíritus has sometimes wrongfully been critically condemned as a mere facsimile of García Màrquez's seminal Latin American novel. However, if critics were to reexamine La casa de los espíritus as a work of fiction in which its writer attempts to give voice to, and achieve personal closure of, historical events so tragically real for her, its comparisons with that "other" Latin American novel might be less frequent. This article contends that Allende uses a mixture of traceable historical facts, unsubstantiated personal accounts, and urban myths perpetuated by popular hearsay to present a plausible version of what could have happened during the events surrounding the fall of Salvador Allende on September 11, 1973. The crux of the argument presented will be that by superimposing unsubstantiated or distorted fact and local myth, Allende calls into play an understanding of traceable historical referents and creates a sense of associative identification between the reader and the text and the characters within. This reconstituted image provides a reinterpretation of what happened, a plausible scenario by means of which one can negotiate or interpret the varying shades of "truth" associated with the events as they may have occurred. This article further argues that through the use of familiar and identifiable images of a closer-to-the-fact fictionalization of real historical incidences, Allende is able to create a more credible characterization and historicity in the novel as well as sensitise her target reader to the resultant social and political changes of what many of her countrymen consider the single most fateful day in their nation's history.

  8. Studies on improved Agrobacterium-mediated transformation in two ...

    African Journals Online (AJOL)

    Administrator

    168-169. Saharan V,Yadav RC,Yadav NR, Chapagain BP (2004). High frequency plant regeneration from desiccated calli of indica rice. (Oryza sativa L.). Afr. J. Biotechnol. 3:256-259. Sivamani E, Huet H, Shen P, Ong C, Kochko A, Beachy RN ...

  9. Facilitation of learning: part 1.

    Science.gov (United States)

    Warburton, Tyler; Trish, Houghton; Barry, Debbie

    2016-04-06

    This article, the fourth in a series of 11, discusses the context for the facilitation of learning. It outlines the main principles and theories for understanding the process of learning, including examples which link these concepts to practice. The practical aspects of using these theories in a practice setting will be discussed in the fifth article of this series. Together, these two articles will provide mentors and practice teachers with knowledge of the learning process, which will enable them to meet the second domain of the Nursing and Midwifery Council's Standards to Support Learning and Assessment in Practice on facilitation of learning.

  10. Avaliação do potencial de cinco cultivares de videiras americanas para sucos de uva no sul de Minas Gerais Potential evaluation of five american cultivars for grape juices in the south of Minas Gerais state

    Directory of Open Access Journals (Sweden)

    Giuliano Elias Pereira

    2008-10-01

    Full Text Available Objetivou-se, no presente trabalho realizar uma caracterização dos sucos de uva de cinco cultivares de videira americana Vitis labrusca (Folha de Figo, Alwood, Concord, BRS-Rúbea e Isabel segundo suas características visuais, olfativas e gustativas, utilizando um método descritivo por um painel de degustadores da Embrapa Uva e Vinho (EMBRAPA/CNPUV de Bento Gonçalves e da Associação Brasileira de Enologia (ABE, constituído por doze degustadores. De acordo com os resultados, os sucos das cultivares Isabel e Folha de Figo foram superiores aos demais, segundo a análise de componentes principais (ACP, principalmente pelas variáveis limpidez, equilíbrio olfativo, intensidade e corpo gustativo, persistência olfato-gustativa e julgamento geral (notas. O suco Folha de Figo foi superior ao Isabel quanto à tonalidade, sendo o primeiro caracterizado como vermelho-violáceo. A cultivar Folha de Figo é a mais utilizada na região para a produção de suco, podendo os produtores utilizarem também a cultivar Isabel, que mostrou potencial nas condições edafo-climáticas do sul de Minas Gerais.The present work was designed to accomplish the characterization of the different grape juices of five grapevine cultivars of Vitis labrusca (Folha de Figo, Alwood, Concord, BRS-Rúbea e Isabel according to their visual, smell and taste characteristics utilizing a descriptive method by a panel of tasters of Embrapa Grape and Wine (EMBRAPA/CNPUV of Bento Gonçalves, and of the Brazilian Enology Association (ABE consisting of 12 tasters. According to the results, the juices of the cultivars Isabel and Folha de Figo were higher than the others, analyzed statistically according to the Principal Component Analysis (PCA, mainly by the visual cleanliness variables, olfatory equilibrium, gustative body and quality, olfato-gustative persistence and general judgement (scores and the juice of Folha de Figo was higher than Isabel according to visual shade, the former

  11. Effect of Intramolecular Dispersion Interactions on the Conformational Preferences of Monoterpenoids

    Science.gov (United States)

    Loru, Donatella; Vigorito, Annalisa; Santos, Andreia; Tang, Jackson; Sanz, M. Eugenia

    2017-06-01

    The rotational spectra of several monoterpenoids have been reinvestigated with a 2-8 GHz chirped pulse FTMW spectrometer. Axial conformers, in addition to previously reported equatorial conformers, have been detected for carvone, perillaldehyde, and limonene. Observation of the ^{13}C isotopologues of these monoterpenoids in their natural abundances allowed the determination of r_s and r_0 structures. Axial conformers are stabilised by dispersion interactions between the six-membered ring of the monoterpenoids and the isopropenyl group. Comparison of experimental data with ab initio and density functional calculations shows that an accurate description of dispersion interactions is still a challenge for theoretical methods. J. R. Avilés Moreno, F. Partal Ureña, J. J. López González and T. R. Huet, Chem. Phys. Lett., 2009, 473, 17-20. J. R. Avilés Moreno, T. R. Huet and J. J. López González, Struct. Chem., 2013, 24, 1163-1170.

  12. Deficits in learning and memory in mice with a mutation of the candidate dyslexia susceptibility gene Dyx1c1.

    Science.gov (United States)

    Rendall, Amanda R; Tarkar, Aarti; Contreras-Mora, Hector M; LoTurco, Joseph J; Fitch, R Holly

    2017-09-01

    Dyslexia is a learning disability characterized by difficulty learning to read and write. The underlying biological and genetic etiology remains poorly understood. One candidate gene, dyslexia susceptibility 1 candidate 1 (DYX1C1), has been shown to be associated with deficits in short-term memory in dyslexic populations. The purpose of the current study was to examine the behavioral phenotype of a mouse model with a homozygous conditional (forebrain) knockout of the rodent homolog Dyx1c1. Twelve Dyx1c1 conditional homozygous knockouts, 7 Dyx1c1 conditional heterozygous knockouts and 6 wild-type controls were behaviorally assessed. Mice with the homozygous Dyx1c1 knockout showed deficits on memory and learning, but not on auditory or motor tasks. These findings affirm existing evidence that DYX1C1 may play an underlying role in the development of neural systems important to learning and memory, and disruption of this function could contribute to the learning deficits seen in individuals with dyslexia. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. CACNA1C gene regulates behavioral strategies in operant rule learning.

    Science.gov (United States)

    Koppe, Georgia; Mallien, Anne Stephanie; Berger, Stefan; Bartsch, Dusan; Gass, Peter; Vollmayr, Barbara; Durstewitz, Daniel

    2017-06-01

    Behavioral experiments are usually designed to tap into a specific cognitive function, but animals may solve a given task through a variety of different and individual behavioral strategies, some of them not foreseen by the experimenter. Animal learning may therefore be seen more as the process of selecting among, and adapting, potential behavioral policies, rather than mere strengthening of associative links. Calcium influx through high-voltage-gated Ca2+ channels is central to synaptic plasticity, and altered expression of Cav1.2 channels and the CACNA1C gene have been associated with severe learning deficits and psychiatric disorders. Given this, we were interested in how specifically a selective functional ablation of the Cacna1c gene would modulate the learning process. Using a detailed, individual-level analysis of learning on an operant cue discrimination task in terms of behavioral strategies, combined with Bayesian selection among computational models estimated from the empirical data, we show that a Cacna1c knockout does not impair learning in general but has a much more specific effect: the majority of Cacna1c knockout mice still managed to increase reward feedback across trials but did so by adapting an outcome-based strategy, while the majority of matched controls adopted the experimentally intended cue-association rule. Our results thus point to a quite specific role of a single gene in learning and highlight that much more mechanistic insight could be gained by examining response patterns in terms of a larger repertoire of potential behavioral strategies. The results may also have clinical implications for treating psychiatric disorders.

  14. Deleting Both PHLPP1 and CANP1 Rescues Impairments in Long-Term Potentiation and Learning in Both Single Knockout Mice

    Science.gov (United States)

    Liu, Yan; Sun, Jiandong; Wang, Yubin; Lopez, Dulce; Tran, Jennifer; Bi, Xiaoning; Baudry, Michel

    2016-01-01

    Calpain-1 (CANP1) has been shown to play a critical role in synaptic plasticity and learning and memory, as its deletion in mice results in impairment in theta-burst stimulation (TBS)-induced LTP and various forms of learning and memory. Likewise, PHLPP1 (aka SCOP) has also been found to participate in learning and memory, as PHLPP1 overexpression…

  15. Gestión interactoral del hábitat a nivel barrial. Prácticas profesionales en Barrio Santa Isabel - Córdoba

    Directory of Open Access Journals (Sweden)

    Pedro Cufré

    2006-01-01

    Full Text Available Tradicionalmente la vivienda ha sido concebida como mero objeto físico, dejando al margen el concepto social de la vivienda y su papel para satisfacer necesidades humanas. Por ello resulta fundamental promover desde los ámbitos locales abordajes integrales (propuestas que partiendo de la vivienda como proceso social incorporen otros objetivos, y un notable nivel de participación y articulación de actores (gestión asociada. La vivienda se transforma así en un instrumento que permite la implementación de procesos constructivoeducativos tendientes a descubrir y desarrollar las potencialidades locales, como así también dejar instaladas capacidades, no sólo en la comunidad sino en los equipos técnicos involucrados. Bajo esta concepción, el Servicio Socio-Habitacional (SSH de la Facultad de Arquitectura de la Universidad Católica de Córdoba, a través de la metodología de aprendizaje-servicio, ha desarrollado durante los años 2004-2005 sus actividades de formación y acción conjuntamente con la Junta de Participación Ciudadana de Barrio Santa Isabel de la ciudad de Córdoba. A través de la complementación de los aportes no sólo de cada una de las áreas de la carrera sino de diversos actores sociales, se han desarrollado variadas acciones desde una visión integral a partir de la especificidad arquitectónica, llegando a constituirse en una de las cinco Mejores Prácticas Educativas Solidarias del país. Estas acciones se encuadran dentro de una discusión conceptual, que partiendo de la naturaleza misma de la problemática existente, intenta impulsar un cambio de conciencia respecto a la necesidad de superar enfoques sectoriales, favoreciendo una formación académicoprofesional específicamente capacitada y comprometida en acciones que tiendan a superarla.

  16. Naturaleza y significado de los libros de cuentas de John Isham, mercader de Isabel I, Reina de Inglaterra

    Directory of Open Access Journals (Sweden)

    Juan Lanero Fernández

    2005-12-01

    Full Text Available De todos los libros de cuentas de John Isham tan sólo se conservan dos Libros Mayores. Representan el esfuerzo continuado, durante un intervalo de doce años, para confeccionar un balance de situación. Es indudable que John Isham se había familiarizado con los rudimentos del arte de la teneduría de libros durante su periodo de aprendiz, bajo la supervisión de su patrón, probablemente en Amberes. El uso que hace de la partida doble, aunque sólo ocupa una pequeña parte del primer Libro Mayor y ninguna del segundo, indica que apostaba por el progreso.El valor de estos dos Libros Mayores del siglo XVI es grande, pues nos dice mucho de la estructura de la exportación de paños, usos que un mercader mediano hace de su capital y otros aspectos dfíciles de averiguar por otras vías. En ambos volúmenes las partidas recogen multitud de detalles que nos hablan del entramado del comercio internacional inglés en el floreciente reinado de Isabel I. Al lado de la parida dole aparecen las compañías gremiales que concedieron al comercio inglés la fueza y el esplendor sobre los que se asentó el Imperio Británico.Out of all the account books of John Isham, only two ledgers are preserved at present. They represent a constant effort, for a twelve-year interval, in order to produce a balance sheet. John Isham, no doubt, had learnt the technicalities of the art of bookkeeping duritng his appenticeship period, under his master's supervision, probably in Antwerp. His use of the double entry system, despite it si only present in some sections of the first ledger and none of the second, it is a clear indication that he favoured progress.The value of these two ledgers is remarkable. They talk about the structure of cloth exportation, how a medium-sized merchant used his capital and some other aspects which are difficult to find out through other means. In both volumes entries release multiple details which tell us about the international English commerce

  17. The Effectiveness of KNOS-KGS Learning Model to Improve Generic Science Skill and Biology Student Learning Outcomes SMA PGRI 1 Banjarmasin

    OpenAIRE

    Nefianthi, Rezky

    2015-01-01

    This study aims to determine the effectiveness of the model KNOS-KGS, to improve the learning outcomes of Biology at the ecosystem material in class X SMA PGRI 1 Banjarmasin. This research is a classroom action research, conducted in two cycles. Each cycle is done with two meetings. This study was conducted on 25 students in class X1. The research data is the result of student learning that consists of cognitive learning outcomes such as pretest and posttest. Affective learning outcomes such ...

  18. Michigan Journal of Community Service Learning. Volume 13, Number 1, Fall 2006

    Science.gov (United States)

    Howard, Jeffrey, Ed.

    2006-01-01

    The "Michigan Journal of Community Service Learning" ("MJCSL") is a national, peer-reviewed journal consisting of articles written by faculty and service-learning educators on research, theory, pedagogy, and issues pertinent to the service-learning community. The "MJCSL" aims to: (1) widen the community of…

  19. EOL-1, the homolog of the mammalian Dom3Z, regulates olfactory learning in C. elegans

    OpenAIRE

    Zhang, J; Calarco, JA; Shen, Y; Zhang, Y

    2014-01-01

    Learning is an essential function of the nervous system. However, our understanding of molecular underpinnings of learning remains incomplete. Here, we characterize a conserved protein EOL-1 that regulates olfactory learning in Caenorhabditis elegans. A recessive allele of eol-1 (enhanced olfactory learning) learns better to adjust its olfactory preference for bacteria foods and eol-1 acts in the URX sensory neurons to regulate learning. The mammalian homolog of EOL-1, Dom3Z, which regulates ...

  20. Analyzing and Evaluating the 1:1 Learning Model: What Would Dewey Do?

    Science.gov (United States)

    Boulden, Danielle Cadieux

    2017-01-01

    One-to-one computing models, in which every student in a classroom is provided access to a digital device for instruction, have gained traction and popularity as an instructional model across United States classrooms and around the globe. This paper explores and evaluates these 1:1 computing models in K-12 learning environments through the lens of…

  1. L1-norm locally linear representation regularization multi-source adaptation learning.

    Science.gov (United States)

    Tao, Jianwen; Wen, Shiting; Hu, Wenjun

    2015-09-01

    In most supervised domain adaptation learning (DAL) tasks, one has access only to a small number of labeled examples from target domain. Therefore the success of supervised DAL in this "small sample" regime needs the effective utilization of the large amounts of unlabeled data to extract information that is useful for generalization. Toward this end, we here use the geometric intuition of manifold assumption to extend the established frameworks in existing model-based DAL methods for function learning by incorporating additional information about the target geometric structure of the marginal distribution. We would like to ensure that the solution is smooth with respect to both the ambient space and the target marginal distribution. In doing this, we propose a novel L1-norm locally linear representation regularization multi-source adaptation learning framework which exploits the geometry of the probability distribution, which has two techniques. Firstly, an L1-norm locally linear representation method is presented for robust graph construction by replacing the L2-norm reconstruction measure in LLE with L1-norm one, which is termed as L1-LLR for short. Secondly, considering the robust graph regularization, we replace traditional graph Laplacian regularization with our new L1-LLR graph Laplacian regularization and therefore construct new graph-based semi-supervised learning framework with multi-source adaptation constraint, which is coined as L1-MSAL method. Moreover, to deal with the nonlinear learning problem, we also generalize the L1-MSAL method by mapping the input data points from the input space to a high-dimensional reproducing kernel Hilbert space (RKHS) via a nonlinear mapping. Promising experimental results have been obtained on several real-world datasets such as face, visual video and object. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Emotional Dynamics in Conflict and Conflict Transformation

    DEFF Research Database (Denmark)

    Poder, Poul; Bramsen, Isabel

    2018-01-01

    Isabel Bramsen & Poul Poder 2018. Emotional Dynamics in Conflict and Conflict Transformation. Berghof Handbook for Conflict Transformation, Online Edition. Berlin: Berghof Foundation. Isabel Bramsen & Poul Poder 2018. Emotional Dynamics in Conflict and Conflict Transformation. Berghof Handbook for Conflict Transformation, Online Edition. Berlin: Berghof Foundation.

  3. Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity.

    Science.gov (United States)

    Kim, Hui Kwon; Min, Seonwoo; Song, Myungjae; Jung, Soobin; Choi, Jae Woo; Kim, Younggwang; Lee, Sangeun; Yoon, Sungroh; Kim, Hyongbum Henry

    2018-03-01

    We present two algorithms to predict the activity of AsCpf1 guide RNAs. Indel frequencies for 15,000 target sequences were used in a deep-learning framework based on a convolutional neural network to train Seq-deepCpf1. We then incorporated chromatin accessibility information to create the better-performing DeepCpf1 algorithm for cell lines for which such information is available and show that both algorithms outperform previous machine learning algorithms on our own and published data sets.

  4. EOL-1, the homolog of the mammalian Dom3Z, regulates olfactory learning in C. elegans.

    Science.gov (United States)

    Shen, Yu; Zhang, Jiangwen; Calarco, John A; Zhang, Yun

    2014-10-01

    Learning is an essential function of the nervous system. However, our understanding of molecular underpinnings of learning remains incomplete. Here, we characterize a conserved protein EOL-1 that regulates olfactory learning in Caenorhabditis elegans. A recessive allele of eol-1 (enhanced olfactory learning) learns better to adjust its olfactory preference for bacteria foods and eol-1 acts in the URX sensory neurons to regulate learning. The mammalian homolog of EOL-1, Dom3Z, which regulates quality control of pre-mRNAs, can substitute the function of EOL-1 in learning regulation, demonstrating functional conservation between these homologs. Mutating the residues of Dom3Z that are critical for its enzymatic activity, and the equivalent residues in EOL-1, abolishes the function of these proteins in learning. Together, our results provide insights into the function of EOL-1/Dom3Z and suggest that its activity in pre-mRNA quality control is involved in neural plasticity. Copyright © 2014 the authors 0270-6474/14/3413364-07$15.00/0.

  5. Lessons Learned from the Node 1 Temperature and Humidity Control Subsystem Design

    Science.gov (United States)

    Williams, David E.

    2010-01-01

    Node 1 flew to the International Space Station (ISS) on Flight 2A during December 1998. To date the National Aeronautics and Space Administration (NASA) has learned a lot of lessons from this module based on its history of approximately two years of acceptance testing on the ground and currently its twelve years on-orbit. This paper will provide an overview of the ISS Environmental Control and Life Support (ECLS) design of the Node 1 Temperature and Humidity Control (THC) subsystem and it will document some of the lessons that have been learned to date for this subsystem and it will document some of the lessons that have been learned to date for these subsystems based on problems prelaunch, problems encountered on-orbit, and operational problems/concerns. It is hoped that documenting these lessons learned from ISS will help in preventing them in future Programs. 1

  6. Neurocognitive profiles of learning disabled children with neurofibromatosis type 1

    Directory of Open Access Journals (Sweden)

    Miladys eOrraca-Castillo

    2014-06-01

    Full Text Available Neurofibromatosis 1 (NF1 is a genetic condition generally associated with intellectual deficiency and learning disabilities. Although there have been groundbreaking advances in the understanding of the molecular, cellular, and neural systems underlying learning deficits associated to NF1 in animal models, much remains to be learned about the spectrum of neurocognitive phenotype associated with the NF1 clinical syndrome. In the present study, 32 children with NF1 ranging from 7 to 14 years were evaluated with neurocognitive tests dedicated to assess basic capacities which are involved in reading and mathematical achievement. Deficits in lexical and phonological strategies and poor number facts retrieval were found underlying reading and arithmetic disorders, respectively. Additionally, efficiencies in lexical/phonological strategies and mental arithmetic were significant predictors of individual differences in reading attainment and math. However, deficits in core numeric capacities were not found in the sample, suggesting that it is not responsible for calculation dysfluency. The estimated prevalence of Developmental Dyscalculia was 18.8%, and the male:female ratio was 5:1. On the other hand, the prevalence of Developmental Dyslexia was almost 3 times as high (50%, and no gender differences were found (male:female ratio=1:1. This study offers new evidence to the neurocognitive phenotype of NF1 contributing to an in depth understanding of this condition, but also to possible treatments for the cognitive deficits associated with NF1.

  7. Anodal tDCS to V1 blocks visual perceptual learning consolidation.

    Science.gov (United States)

    Peters, Megan A K; Thompson, Benjamin; Merabet, Lotfi B; Wu, Allan D; Shams, Ladan

    2013-06-01

    This study examined the effects of visual cortex transcranial direct current stimulation (tDCS) on visual processing and learning. Participants performed a contrast detection task on two consecutive days. Each session consisted of a baseline measurement followed by measurements made during active or sham stimulation. On the first day, one group received anodal stimulation to primary visual cortex (V1), while another received cathodal stimulation. Stimulation polarity was reversed for these groups on the second day. The third (control) group of subjects received sham stimulation on both days. No improvements or decrements in contrast sensitivity relative to the same-day baseline were observed during real tDCS, nor was any within-session learning trend observed. However, task performance improved significantly from Day 1 to Day 2 for the participants who received cathodal tDCS on Day 1 and for the sham group. No such improvement was found for the participants who received anodal stimulation on Day 1, indicating that anodal tDCS blocked overnight consolidation of visual learning, perhaps through engagement of inhibitory homeostatic plasticity mechanisms or alteration of the signal-to-noise ratio within stimulated cortex. These results show that applying tDCS to the visual cortex can modify consolidation of visual learning. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. The Port Isabel Fold Belt: Salt enhanced Neogene Gravitational Spreading in the East Breaks, Western Gulf of Mexico

    Science.gov (United States)

    Lebit, Hermann; Clavaud, Marie; Whitehead, Sam; Opdyke, Scott; Luneburg, Catalina

    2017-04-01

    The Port Isabel fold belt is situated at the northwestern corner of the deep water Gulf of Mexico where the regional E-W trending Texas-Louisiana shelf bends into the NNE-SSW trend of the East Mexico Shelf. The fold belt forms an allochthonous wedge that ramps up from West to East with its front occupied by shallow salt complexes (local canopies). It is assumed that the belt predominantly comprises Oligocene siliciclastic sequences which reveal eastward facing folds and thrusts with a NE-SW regional trend. The structural architecture of the fold belt is very well imaged on recently processed 3D seismic volumes. Crystal III is a wide-azimuth survey acquired in 2011 and reprocessed in 2016 leveraging newly developed state-of-the-art technology. 3D deghosting, directional designature and multi-model 3D SRME resulted in broader frequency spectrum. The new image benefits from unique implementation of FWI, combined with classic tomographic updates. Seismically transparent zones indicating over-pressured shales are limited to the core of anticlines or to the footwall of internal thrust. Mobile shales associated with diapirs are absent in the study area. In contrast, salt is mobile and apparently forms the major decollement of the PIFB as indicated by remnant salt preferentially located in triangles along the major thrusts and fault intersections or at the core of anticlines. Shallow salt diapirs seam to root in the fold belt, while lacking evidence for salt feeders being connected to the deep salt underlying the Mesozoic to Paleogene substratum of the fold belt. Towards the WNW the fold belt is transient into a extensional regime, characterized by roll-over structures associated with deep reaching normal faults which form ultra-deep mini basins filled with Neogene deposits. Kinematic restorations confirm the simultaneous evolution of the deep mini basins and the outboard fold belt. This resembles a gravitational spreading system with the extensional tectonics of the deep

  9. Learning Based on CC1 and CC4 Neural Networks

    OpenAIRE

    Kak, Subhash

    2017-01-01

    We propose that a general learning system should have three kinds of agents corresponding to sensory, short-term, and long-term memory that implicitly will facilitate context-free and context-sensitive aspects of learning. These three agents perform mututally complementary functions that capture aspects of the human cognition system. We investigate the use of CC1 and CC4 networks for use as models of short-term and sensory memory.

  10. IMPROVING LEARNING PROCESS AND STUDENT RESULTS LEARNING TO TUNE-UPMOTORCYCLE USING DEMONSTRATION METHODOF CLASS XI SMA N 1 PLAYEN YEAR STUDY2013/2014

    Directory of Open Access Journals (Sweden)

    Haryono Haryono

    2014-12-01

    Full Text Available This research is to improve the learning process and results in learning a tune-up motorcycle  using the demonstrationmethod of class XI SMA 1 Playen.              This research is a classroom action research (PTK, using the demonstration method.Subyek this study were students of class XI SMA Negeri 1 Playen.Theimplementationofthisstudyusing3cycles,there is a (planning, implementation (actuating, observation (observing, and reflection (reflecting. Collecting data in this study are observations of student learning process and student learning outcomes test data pre-test, postesI, II, III and documentation as a support to the two data. Further observation data based on the observation of student learning just learning the positive process of learning student and test data were analyzed for comparison. Indicators of success in this classroom action research that student learning increases towards positive along with the use of methods of demonstration, is to see an increase from the pre-cycle to end the first cycle, the first cycle to the second cycle and the secondcyclebycycle III.             From the results of this study concluded that the method could improve the demonstration of positive student learning, from the first cycle of 30%, 50% second cycle and third cycle of 80%. Learning is also more effective with students indicated more quickly adapt as a positive activity, especially in terms of increased student asked, noting the test and work on the problems. Demonstration method can improve the learning outcomes  students of class XI SMA 1 Playen as evidenced by an increase in the average yield final test first cycle of 64.09; second cycle of 77.82 and 78.86 for the third cycle. So it proved with the increasing positive student learning canalso improve student learning outcomes.

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. SARAVANA KUMAR JAGANATHAN. Articles written in Bulletin of Materials Science. Volume 41 Issue 1 February 2018 pp 18. Advanced nanofibrous textile-based dressing material for treating chronic wounds · ISABEL HERRMANN EKO SUPRIYANTO SARAVANA KUMAR ...

  12. Adaptive gain modulation in V1 explains contextual modifications during bisection learning.

    Directory of Open Access Journals (Sweden)

    Roland Schäfer

    2009-12-01

    Full Text Available The neuronal processing of visual stimuli in primary visual cortex (V1 can be modified by perceptual training. Training in bisection discrimination, for instance, changes the contextual interactions in V1 elicited by parallel lines. Before training, two parallel lines inhibit their individual V1-responses. After bisection training, inhibition turns into non-symmetric excitation while performing the bisection task. Yet, the receptive field of the V1 neurons evaluated by a single line does not change during task performance. We present a model of recurrent processing in V1 where the neuronal gain can be modulated by a global attentional signal. Perceptual learning mainly consists in strengthening this attentional signal, leading to a more effective gain modulation. The model reproduces both the psychophysical results on bisection learning and the modified contextual interactions observed in V1 during task performance. It makes several predictions, for instance that imagery training should improve the performance, or that a slight stimulus wiggling can strongly affect the representation in V1 while performing the task. We conclude that strengthening a top-down induced gain increase can explain perceptual learning, and that this top-down signal can modify lateral interactions within V1, without significantly changing the classical receptive field of V1 neurons.

  13. Browse Title Index

    African Journals Online (AJOL)

    Items 1 - 50 of 154 ... Vol 68, No 1 (2015), A preliminary assessment of the palate and tongue for detecting organophosphorus and carbamate pesticide exposure in the degraded carcasses of vultures and other animals, Abstract PDF PDF. Ngaio L Richards, Irene Zorilla, Isabel Fernandez, Monica Calvino, Joaquin Garcia, ...

  14. Teaching & Learning Tips 1: Teaching perspectives - an introduction.

    Science.gov (United States)

    Rana, Jasmine; Burgin, Susan

    2017-11-01

    Challenge: Clinical and research responsibilities often leave little or no time to plan thoughtful teaching encounters with trainees. This "Teaching & Learning Tips" series is designed to be an accessible guide for dermatologists who want to improve their teaching skills. It is comprised of 12 articles about how to enhance teaching in various settings informed by research about how people learn and expert-derived or data-driven best practices for teaching. The series begins with a review of principles to optimize learning in any setting, including cognitive load theory, active learning strategies, and the impact of motivation and emotion on learning. It transitions into a practical "how to" guide format for common teaching scenarios in dermatology, such as lecturing, case-based teaching, and teaching procedures, among others. Herein, we kickoff the series by unpacking assumptions about teaching and learning. What does it mean to teach and learn? © 2017 The International Society of Dermatology.

  15. Spred1 is required for synaptic plasticity and hippocampus-dependent learning

    NARCIS (Netherlands)

    E. Denayer (Ellen); T. Ahmed (Tariq); H. Brems (Hilde); G.M. van Woerden (Geeske); N.Z. Borgesius; Z. Callaerts-Vegh (Zsuzsanna); A. Yoshimura (Akihiko); D. Hartmann (Dieter); Y. Elgersma (Ype); R. D'Hooge (Rudi); E. Legius (Eric); D. Balschun (Detlef)

    2008-01-01

    textabstractGermline mutations in SPRED1, a negative regulator of Ras, have been described in a neurofibromatosis type 1 (NF1)-like syndrome (NFLS) that included learning difficulties in some affected individuals. NFLS belongs to the group of phenotypically overlapping neurocardio-facial-cutaneous

  16. DAT1 polymorphism determines L-DOPA effects on learning about others' prosociality.

    Directory of Open Access Journals (Sweden)

    Christoph Eisenegger

    Full Text Available Despite that a wealth of evidence links striatal dopamine to individualś reward learning performance in non-social environments, the neurochemical underpinnings of such learning during social interaction are unknown. Here, we show that the administration of 300 mg of the dopamine precursor L-DOPA to 200 healthy male subjects influences learning about a partners' prosocial preferences in a novel social interaction task, which is akin to a repeated trust game. We found learning to be modulated by a well-established genetic marker of striatal dopamine levels, the 40-bp variable number tandem repeats polymorphism of the dopamine transporter (DAT1 polymorphism. In particular, we found that L-DOPA improves learning in 10/10R genoype subjects, who are assumed to have lower endogenous striatal dopamine levels and impairs learning in 9/10R genotype subjects, who are assumed to have higher endogenous dopamine levels. These findings provide first evidence for a critical role of dopamine in learning whether an interaction partner has a prosocial or a selfish personality. The applied pharmacogenetic approach may open doors to new ways of studying psychiatric disorders such as psychosis, which is characterized by distorted perceptions of others' prosocial attitudes.

  17. Neuronal Rac1 is required for learning-evoked neurogenesis

    DEFF Research Database (Denmark)

    Haditsch, Ursula; Anderson, Matthew P; Freewoman, Julia

    2013-01-01

    Hippocampus-dependent learning and memory relies on synaptic plasticity as well as network adaptations provided by the addition of adult-born neurons. We have previously shown that activity-induced intracellular signaling through the Rho family small GTPase Rac1 is necessary in forebrain projection...

  18. Learning sequences on the subject of energy. Secondary school stage 1. Lernsequenzen zum Thema Energie. Sekundarstufe 1

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    The ten learning sequences follow on one another. Each picks on a particular aspect from the energy field. The subject notebooks are self-contained and can therefore be used independently. Apart from actual data and energy-related information, the information for the teacher contains: - proposals for teaching - suggestions for further activities - sample solutions for the pupil's sheets - references to the literature and media. The worksheets for the pupils are different; it should be possible to use the learning sequences in all classes of secondary school stage 1. The multicoloured foils for projectors should motivate, on the one hand, and on the other hand should help to check the results of learning.

  19. NCS-1 dependent learning bonus and behavior outputs of self-directed exploration

    Science.gov (United States)

    Mun, Ho-Suk

    Animals explore a new environment and learn about their surroundings. "Exploration" refers to all activities that increase the information obtained from an animal. For this study, I determined a molecule that mediates self-directed exploration, with a particular focus on rearing behavior and vocalization. Rearing can be either self-directed exploration or escape-oriented exploration. Self-directed exploration can be driven by the desire to gather information about environments while escape-oriented exploration can be driven by fear or anxiety. To differentiate between these two concepts, I compared rearing and other behaviors in three different conditions 1) novel dim (safe environment), which induces exploration based rearing; 2) novel bright (fearful environment), which elicits fear driven rearing; and 3) familiar environment as a control. First, I characterized the effects on two distinct types of environment in exploratory behavior and its effect on learning. From this, I determined that self-directed exploration enhances spatial learning while escape-oriented exploration does not produce a learning bonus. Second, I found that NCS-1 is involved in exploration, as well as learning and memory, by testing mice with reduced levels of Ncs-1 by point mutation and also siRNA injection. Finally, I illustrated other behavior outputs and neural substrate activities, which co-occurred during either self-directed or escape-oriented exploration. I found that high-frequency ultrasonic vocalizations occurred during self-directed exploration while low-frequency calls were emitted during escape-oriented exploration. Also, with immediate early gene imaging techniques, I found hippocampus and nucleus accumbens activation in self-directed exploration. This study is the first comprehensive molecular analysis of learning bonus in self-directed exploration. These results may be beneficial for studying underlying mechanisms of neuropsychiatric disease, and also reveal therapeutic

  20. Task-specificity of unilateral anodal and dual-M1 tDCS effects on motor learning.

    Science.gov (United States)

    Karok, Sophia; Fletcher, David; Witney, Alice G

    2017-01-08

    Task-specific effects of transcranial direct current stimulation (tDCS) on motor learning were investigated in 30 healthy participants. In a sham-controlled, mixed design, participants trained on 3 different motor tasks (Purdue Pegboard Test, Visuomotor Grip Force Tracking Task and Visuomotor Wrist Rotation Speed Control Task) over 3 consecutive days while receiving either unilateral anodal over the right primary motor cortex (M1), dual-M1 or sham stimulation. Retention sessions were administered 7 and 28 days after the end of training. In the Purdue Pegboard Test, both anodal and dual-M1 stimulation reduced average completion time approximately equally, an improvement driven by online learning effects and maintained for about 1 week. The Visuomotor Grip Force Tracking Task and the Visuomotor Wrist Rotation Speed Control Task were associated with an advantage of dual-M1 tDCS in consolidation processes both between training sessions and when testing at long-term retention; both were maintained for at least 1 month. This study demonstrates that M1-tDCS enhances and sustains motor learning with different electrode montages. Stimulation-induced effects emerged at different learning phases across the tasks, which strongly suggests that the influence of tDCS on motor learning is dynamic with respect to the functional recruitment of the distributed motor system at the time of stimulation. Divergent findings regarding M1-tDCS effects on motor learning may partially be ascribed to task-specific consequences and the effects of offline consolidation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Students' Learning with the Connected Chemistry (CC1) Curriculum: Navigating the Complexities of the Particulate World

    Science.gov (United States)

    Levy, Sharona T.; Wilensky, Uri

    2009-01-01

    The focus of this study is students' learning with a Connected Chemistry unit, CC1 (denotes Connected Chemistry, chapter 1), a computer-based environment for learning the topics of gas laws and kinetic molecular theory in chemistry (Levy and Wilensky 2009). An investigation was conducted into high-school students' learning with Connected…

  2. Constellation Program: Lessons Learned. Volume 1; Executive Summary

    Science.gov (United States)

    Rhatigan, Jennifer L. (Editor)

    2011-01-01

    This document (Volume I) provides an executive summary of the lessons learned from the Constellation Program. A companion Volume II provides more detailed analyses for those seeking further insight and information. In this volume, Section 1.0 introduces the approach in preparing and organizing the content to enable rapid assimilation of the lessons. Section 2.0 describes the contextual framework in which the Constellation Program was formulated and functioned that is necessary to understand most of the lessons. Context of a former program may seem irrelevant in the heady days of new program formulation. However, readers should take some time to understand the context. Many of the lessons would be different in a different context, so the reader should reflect on the similarities and differences in his or her current circumstances. Section 3.0 summarizes key findings developed from the significant lessons learned at the program level that appear in Section 4.0. Readers can use the key findings in Section 3.0 to peruse for particular topics, and will find more supporting detail and analyses in Section 4.0 in a topical format. Appendix A contains a white paper describing the Constellation Program formulation that may be of use to readers wanting more context or background information. The reader will no doubt recognize some very similar themes from previous lessons learned, blue-ribbon committee reviews, National Academy reviews, and advisory panel reviews for this and other large-scale human spaceflight programs; including Apollo, Space Shuttle, Shuttle/Mir, and the ISS. This could represent an inability to learn lessons from previous generations; however, it is more likely that similar challenges persist in the Agency structure and approach to program formulation, budget advocacy, and management. Perhaps the greatest value of these Constellation lessons learned can be found in viewing them in context with these previous efforts to guide and advise the Agency and its

  3. α1-Adrenoceptors in the hippocampal dentate gyrus involved in learning-dependent long-term potentiation during active-avoidance learning in rats.

    Science.gov (United States)

    Lv, Jing; Zhan, Su-Yang; Li, Guang-Xie; Wang, Dan; Li, Ying-Shun; Jin, Qing-Hua

    2016-11-09

    The hippocampus is the key structure for learning and memory in mammals and long-term potentiation (LTP) is an important cellular mechanism responsible for learning and memory. The influences of norepinephrine (NE) on the modulation of learning and memory, as well as LTP, through β-adrenoceptors are well documented, whereas the role of α1-adrenoceptors in learning-dependent LTP is not yet clear. In the present study, we measured extracellular concentrations of NE in the hippocampal dentate gyrus (DG) region using an in-vivo brain microdialysis and high-performance liquid chromatography techniques during the acquisition and extinction of active-avoidance behavior in freely moving conscious rats. Next, the effects of prazosin (an antagonist of α1-adrenoceptor) and phenylephrine (an agonist of the α1-adrenoceptor) on amplitudes of field excitatory postsynaptic potential were measured in the DG region during the active-avoidance behavior. Our results showed that the extracellular concentration of NE in the DG was significantly increased during the acquisition of active-avoidance behavior and gradually returned to the baseline level following extinction training. A local microinjection of prazosin into the DG significantly accelerated the acquisition of the active-avoidance behavior, whereas a local microinjection of phenylephrine retarded the acquisition of the active-avoidance behavior. Furthermore, in all groups, the changes in field excitatory postsynaptic potential amplitude were accompanied by corresponding changes in active-avoidance behavior. Our results suggest that NE activation of α1-adrenoceptors in the hippocampal DG inhibits active-avoidance learning by modulation of synaptic efficiency in rats.

  4. Contextual Learning Requires Functional Diversity at Excitatory and Inhibitory Synapses onto CA1 Pyramidal Neurons

    Directory of Open Access Journals (Sweden)

    Dai Mitsushima

    2015-01-01

    Full Text Available Although the hippocampus is processing temporal and spatial information in particular context, the encoding rule creating memory is completely unknown. To examine the mechanism, we trained rats on an inhibitory avoidance (IA task, a hippocampus-dependent rapid one-trial contextual learning paradigm. By combining Herpes virus-mediated in vivo gene delivery with in vitro patch-clamp recordings, I reported contextual learning drives GluR1-containing AMPA receptors into CA3-CA1 synapses. The molecular event is required for contextual memory, since bilateral expression of delivery blocker in CA1 successfully blocked IA learning. Moreover, I found a logarithmic correlation between the number of delivery blocking cells and learning performance. Considering that one all-or-none device can process 1-bit of data per clock (Nobert Wiener 1961, the logarithmic correlation may provides evidence that CA1 neurons transmit essential data of contextual information. Further, I recently reported critical role of acetylcholine as an intrinsic trigger of learning-dependent synaptic plasticity. IA training induced ACh release in CA1 that strengthened not only AMPA receptor-mediated excitatory synapses, but also GABAA receptor-mediated inhibitory synapses on each CA1 neuron. More importantly, IA-trained rats showed individually different excitatory and inhibitory synaptic inputs with wide variation on each CA1 neuron. Here I propose a new hypothesis that the diversity of synaptic inputs on CA1 neurons may depict cell-specific outputs processing experienced episodes after training.

  5. SEPHYRES 1: A Symptom Checker based on Semantic Pain Descriptors and Weight Spreading

    Directory of Open Access Journals (Sweden)

    Ali SANAEIFAR

    2016-12-01

    Full Text Available Semantic-enabled medical diagnostic systems, which have exploited an ontology in their internal engines, have failed to perfectly describe disease profiles, especially in complex medical terms having a variant generality level or certainty in the medical literature. The main objective of this paper was to present an ontology with a highly matching grade of proeminent medical concepts able to analyze the patient’s descriptive medical condition. Focusing on semantic pain descriptors and weight spreading techniques, we proposed a semantic-pseudo-fuzzy engine entitled SEPHYRES, with which we tried to present an ontology-based solution using not only a generic semantic reasoner but also complementary domain-heuristic reasoning. Having applied the valid evidence-based references along with local experts, we illustrated how the resilient expressive model represents the complex medical term relations. The twenty test cases were extracted from the MEDSCAPE and PubMed databases and the precision and recall were calculated. Finally, the results were compared against the Isabel symptom checker and performed the Wilcoxon signed-rank test. The recall measures indicated that the accuracy was equal to 75%, if the system was adjusted to only ten results as differential diagnoses. Moreover, the Wilcoxon signed-rank test showed that there was significant difference between SEPHYRES and Isabel symptom checker (P= 0.016 so that this method is sufficiently able to improve semantic expressiveness in both professional medical diagnosis and patient decision aid systems.

  6. TENCompetence Learning Design Runtime v.1.3

    NARCIS (Netherlands)

    Sharples, Paul; Beauvoir, Phillip; Cherian, Roy; Griffiths, David; Gueorguiev, Atenas; Hernández-Leo, Davinia; Melero, Javier; Miao, Yongwu; Santos, Patricia; Wilson, Scott

    2009-01-01

    These server applications provide runtime support for IMS-LD Units of Learning, widget based services for Units of Learning, and IMS-QTI. Available under the three clause BSD licence, Copyright TENCompetence Foundation. The used CopperCore service has a GPL license.

  7. Specialized motor-driven dusp1 expression in the song systems of multiple lineages of vocal learning birds.

    Directory of Open Access Journals (Sweden)

    Haruhito Horita

    Full Text Available Mechanisms for the evolution of convergent behavioral traits are largely unknown. Vocal learning is one such trait that evolved multiple times and is necessary in humans for the acquisition of spoken language. Among birds, vocal learning is evolved in songbirds, parrots, and hummingbirds. Each time similar forebrain song nuclei specialized for vocal learning and production have evolved. This finding led to the hypothesis that the behavioral and neuroanatomical convergences for vocal learning could be associated with molecular convergence. We previously found that the neural activity-induced gene dual specificity phosphatase 1 (dusp1 was up-regulated in non-vocal circuits, specifically in sensory-input neurons of the thalamus and telencephalon; however, dusp1 was not up-regulated in higher order sensory neurons or motor circuits. Here we show that song motor nuclei are an exception to this pattern. The song nuclei of species from all known vocal learning avian lineages showed motor-driven up-regulation of dusp1 expression induced by singing. There was no detectable motor-driven dusp1 expression throughout the rest of the forebrain after non-vocal motor performance. This pattern contrasts with expression of the commonly studied activity-induced gene egr1, which shows motor-driven expression in song nuclei induced by singing, but also motor-driven expression in adjacent brain regions after non-vocal motor behaviors. In the vocal non-learning avian species, we found no detectable vocalizing-driven dusp1 expression in the forebrain. These findings suggest that independent evolutions of neural systems for vocal learning were accompanied by selection for specialized motor-driven expression of the dusp1 gene in those circuits. This specialized expression of dusp1 could potentially lead to differential regulation of dusp1-modulated molecular cascades in vocal learning circuits.

  8. Effects of microwave exposure on glucagon-like peptide-1 (GLP-1) and its receptor and the relationship with learning and memory injury

    International Nuclear Information System (INIS)

    Zhang Lei; Zhou Zhou; Zhang Guangbin; Yu Zhengping

    2007-01-01

    In order to explore the effects of microwave exposure on GLP-1 and its receptor, the relationship between the changes of GLP-1 and its receptor and learning and memory injury induced by microwave exposure has been studied in this paper. Morris water maze was used to evaluate learning and memory ability of rats. The changes of the plasma GLP-1 level were measured by ELISA assay. Alteration of the GLP-1R mRNA expression in rat hippocampus was determined by RT-PCR and Apoptosis was detected by TUNEL. Our study showed that microwave exposure injured the learning and memory abilities of rats meanwhile plasma GLP-1 level was decreased and GLP-1R expression in hippocampus was down-regulated, which can be protected by pretreatment with GLP-1. Alterations in GLP-1 and GLP-1R are, at least partially, responsible for the microwave exposure induced learning and memory dysfunction and neuronal injury. These data provide some new clues to investigate the mechanisms of microwave exposure induced neuronal injury and develop clinical approaches for treatment of microwave exposure induced injury. It can provide some new ideals for investigation of related mechanism and development of clinical treatment under exposed microwave irradiation. (authors)

  9. Operant learning and differential-reinforcement-of-low-rate 36-s responding in 5-HT1A and 5-HT1B receptor knockout mice.

    NARCIS (Netherlands)

    Pattij, T.; Broersen, L.M.; Linde, J. van der; Groenink, L.; Gugten, J. van der; Maes, R.A.A.; Olivier, B.

    2003-01-01

    Previous studies with mice lacking 5-HT(1A) (1AKO) and 5-HT(1B) (1BKO) receptors in hippocampus-dependent learning and memory paradigms, suggest that these receptors play an important role in learning and memory, although their precise role is unclear. In the present study, 1AKO and 1BKO mice were

  10. Resource Letter ALIP-1: Active-Learning Instruction in Physics

    Science.gov (United States)

    Meltzer, David E.; Thornton, Ronald K.

    2012-06-01

    This Resource Letter provides a guide to the literature on research-based active-learning instruction in physics. These are instructional methods that are based on, assessed by, and validated through research on the teaching and learning of physics. They involve students in their own learning more deeply and more intensely than does traditional instruction, particularly during class time. The instructional methods and supporting body of research reviewed here offer potential for significantly improved learning in comparison to traditional lecture-based methods of college and university physics instruction. We begin with an introduction to the history of active learning in physics in the United States, and then discuss some methods for and outcomes of assessing pedagogical effectiveness. We enumerate and describe common characteristics of successful active-learning instructional strategies in physics. We then discuss a range of methods for introducing active-learning instruction in physics and provide references to those methods for which there is published documentation of student learning gains.

  11. The Future of Learning: From eLearning to mLearning.

    Science.gov (United States)

    Keegan, Desmond

    The future of electronic learning was explored in an analysis that viewed the provision of learning at a distance as a continuum and traced the evolution from distance learning to electronic learning to mobile learning in Europe and elsewhere. Special attention was paid to the following topics: (1) the impact of the industrial revolution, the…

  12. 1st International Conference on Machine Learning for Cyber Physical Systems and Industry 4.0

    CERN Document Server

    Beyerer, Jürgen

    2016-01-01

    The work presents new approaches to Machine Learning for Cyber Physical Systems, experiences and visions. It contains some selected papers from the international Conference ML4CPS – Machine Learning for Cyber Physical Systems, which was held in Lemgo, October 1-2, 2015. Cyber Physical Systems are characterized by their ability to adapt and to learn: They analyze their environment and, based on observations, they learn patterns, correlations and predictive models. Typical applications are condition monitoring, predictive maintenance, image processing and diagnosis. Machine Learning is the key technology for these developments.

  13. Learning-dependent gene expression of CREB1 isoforms in the molluscan brain

    Directory of Open Access Journals (Sweden)

    Hisayo Sadamoto

    2010-05-01

    Full Text Available Cyclic AMP-responsive element binding protein1 (CREB1 has multiple functions in gene regulation. Various studies have reported that CREB1-dependent gene induction is necessary for memory formation and long-lasting behavioral changes in both vertebrates and invertebrates. In the present study, we characterized Lymnaea CREB1 (LymCREB1 mRNA isoforms of spliced variants in the central nervous system (CNS of the pond snail Lymnaea stagnalis. Among these spliced variants, the three isoforms that code a whole LymCREB1 protein are considered to be the activators for gene regulation. The other four isoforms, which code truncated LymCREB1 proteins with no kinase inducible domain, are the repressors. For a better understanding of the possible roles of different LymCREB1 isoforms, the expression level of these isoform mRNAs was investigated by a real-time quantitative RT-PCR method. Further, we examined the changes in gene expression for all the isoforms in the CNS after conditioned taste aversion (CTA learning or backward conditioning as a control. The results showed that CTA learning increased LymCREB1 gene expression, but it did not change the activator/repressor ratio. Our findings showed that the repressor isoforms, as well as the activator ones, are expressed in large amounts in the CNS, and the gene expression of CREB1 isoforms appeared to be specific for the given stimulus. This was the first quantitative analysis of the expression patterns of CREB1 isoforms at the mRNA level and their association with learning behavior.

  14. Teaching and Learning Physics in a 1:1 Laptop School

    Science.gov (United States)

    Zucker, Andrew A.; Hug, Sarah T.

    2008-12-01

    1:1 laptop programs, in which every student is provided with a personal computer to use during the school year, permit increased and routine use of powerful, user-friendly computer-based tools. Growing numbers of 1:1 programs are reshaping the roles of teachers and learners in science classrooms. At the Denver School of Science and Technology, a public charter high school where a large percentage of students come from low-income families, 1:1 laptops are used often by teachers and students. This article describes the school's use of laptops, the Internet, and related digital tools, especially for teaching and learning physics. The data are from teacher and student surveys, interviews, classroom observations, and document analyses. Physics students and teachers use an interactive digital textbook; Internet-based simulations (some developed by a Nobel Prize winner); word processors; digital drop boxes; email; formative electronic assessments; computer-based and stand-alone graphing calculators; probes and associated software; and digital video cameras to explore hypotheses, collaborate, engage in scientific inquiry, and to identify strengths and weaknesses of students' understanding of physics. Technology provides students at DSST with high-quality tools to explore scientific concepts and the experiences of teachers and students illustrate effective uses of digital technology for high school physics.

  15. Introduction to section 1 - Learning as a process

    DEFF Research Database (Denmark)

    Sriskandarajah, Nadarajah; Cerf, Marianne; Noe, Egon

    2006-01-01

    As an introduction to the workshop where 18 papers and posters were presented on the theme of ‘Learning as a Process’, the linked nature of the learning – knowing – acting field in rural development in Europe is emphasised. The workshop took up the issues of human interactions in foster learning...... processes, capacity building and development of collective action as a bottom-up process....

  16. AMEE Guide 32: e-Learning in medical education Part 1: Learning, teaching and assessment.

    Science.gov (United States)

    Ellaway, Rachel; Masters, Ken

    2008-06-01

    In just a few years, e-learning has become part of the mainstream in medical education. While e-learning means many things to many people, at its heart it is concerned with the educational uses of technology. For the purposes of this guide, we consider the many ways that the information revolution has affected and remediated the practice of healthcare teaching and learning. Deploying new technologies usually introduces tensions, and e-learning is no exception. Some wish to use it merely to perform pre-existing activities more efficiently or faster. Others pursue new ways of thinking and working that the use of such technology affords them. Simultaneously, while education, not technology, is the prime goal (and for healthcare, better patient outcomes), we are also aware that we cannot always predict outcomes. Sometimes, we have to take risks, and 'see what happens.' Serendipity often adds to the excitement of teaching. It certainly adds to the excitement of learning. The use of technology in support of education is not, therefore, a causal or engineered set of practices; rather, it requires creativity and adaptability in response to the specific and changing contexts in which it is used. Medical Education, as with most fields, is grappling with these tensions; the AMEE Guide to e-Learning in Medical Education hopes to help the reader, whether novice or expert, navigate them. This Guide is presented both as an introduction to the novice, and as a resource to more experienced practitioners. It covers a wide range of topics, some in broad outline, and others in more detail. Each section is concluded with a brief 'Take Home Message' which serves as a short summary of the section. The Guide is divided into two parts. The first part introduces the basic concepts of e-learning, e-teaching, and e-assessment, and then focuses on the day-to-day issues of e-learning, looking both at theoretical concepts and practical implementation issues. The second part examines technical

  17. Odor preference learning and memory modify GluA1 phosphorylation and GluA1 distribution in the neonate rat olfactory bulb: testing the AMPA receptor hypothesis in an appetitive learning model.

    Science.gov (United States)

    Cui, Wen; Darby-King, Andrea; Grimes, Matthew T; Howland, John G; Wang, Yu Tian; McLean, John H; Harley, Carolyn W

    2011-01-01

    An increase in synaptic AMPA receptors is hypothesized to mediate learning and memory. AMPA receptor increases have been reported in aversive learning models, although it is not clear if they are seen with memory maintenance. Here we examine AMPA receptor changes in a cAMP/PKA/CREB-dependent appetitive learning model: odor preference learning in the neonate rat. Rat pups were given a single pairing of peppermint and 2 mg/kg isoproterenol, which produces a 24-h, but not a 48-h, peppermint preference in the 7-d-old rat pup. GluA1 PKA-dependent phosphorylation peaked 10 min after the 10-min training trial and returned to baseline within 90 min. At 24 h, GluA1 subunits did not change overall but were significantly increased in synaptoneurosomes, consistent with increased membrane insertion. Immunohistochemistry revealed a significant increase in GluA1 subunits in olfactory bulb glomeruli, the targets of olfactory nerve axons. Glomerular increases were seen at 3 and 24 h after odor exposure in trained pups, but not in control pups. GluA1 increases were not seen as early as 10 min after training and were no longer observed 48 h after training when odor preference is no longer expressed behaviorally. Thus, the pattern of increased GluA1 membrane expression closely follows the memory timeline. Further, blocking GluA1 insertion using an interference peptide derived from the carboxyl tail of the GluA1 subunit inhibited 24 h odor preference memory providing causative support for our hypothesis. PKA-mediated GluA1 phosphorylation and later GluA1 insertion could, conjointly, provide increased AMPA function to support both short-term and long-term appetitive memory.

  18. 24 June 2014 - Latin America Ambassadors to Switzerland visiting the LHC tunnel at Point 1 with Beams Department R. A. Fernandez

    CERN Multimedia

    Egli, Laurent

    2014-01-01

    Visitors present in random order: Ambassador Antonio Gustavo Trombetta (Argentina) ; Ambassador Igor Kipman (Brasil) ; Ambassador Beatriz Londoño Soto (Colombia) ; Ambassador Isabel Montero de la Cámara (Costa Rica) ; Ambassador María del Pilar Fernandez Otero (Cuba) ; Ambassador Jorge Castro-Valle Kuehne (México) ; Researcher Luis Roberto Flores Castillo (México) ; Chargé d’affaires Esteban Paez Gonzalez (Paraguay) ; Ambassador Luis Juan Chuquihuara Chil (Perú) ; Ambassador Cesar Osvelio Méndez (Venezuela)

  19. Care work versus career work: sibling conflict over getting priorities right.

    Science.gov (United States)

    Lashewicz, Bonnie

    2011-01-01

    As the average age of the Canadian population continues to increase, and providing care at home to frail older adults becomes ever more prevalent, support for family and friend caregivers remains a key social policy issue. Economic support is an important consideration given the impact of caregiving on labour force participation. Yet the caregiving/paid work relationship is not always straightforward. While caregiving often restricts employment, limited attachment to employment may also influence the decision to provide care. Isabel's story, collected as part of a study of sibling views of fairness in sharing parent care as well as parent assets, provides a case study in how siblings give different priority to care work versus career work and what support needs arise including those related to sibling conflict over differing priorities. Isabel claims she sacrificed her career to care for her ailing mother while her siblings argue that through caregiving, Isabel was sheltered from the paid workforce.

  20. PENGEMBANGAN DAN ANALISIS KUALITAS APLIKASI PENILAIAN E-LEARNING SMK BERBASIS ISO 19796-1 DI YOGYAKARTA

    Directory of Open Access Journals (Sweden)

    Ahmad Faiq Abror

    2016-03-01

    Full Text Available Penelitian ini bertujuan untuk: (1 menghasilkan aplikasi penilaian e-learning Sekolah Menengah Kejuruan (SMK berbasis ISO 19796-1 yang dapat digunakan untuk mengevaluasi e-learning SMK di Yogyakarta menggunakan teknik Analitycal Hierarchy Process (AHP dengan metode agregasi arithmetric mean dan geometric mean, (2 menguji kualitas aplikasi dengan menggunakan strandar ISO 9126. Penelitian ini merupakan penelitian Research and Development (R&D. Proses pengembangan aplikasi menggunakan metode  Software Development Life Cycle (SDLC dengan model Waterfall. Selanjutnya pada proses pengujian kualitas aplikasi menggunakan standar ISO 9126 yang terdiri atas aspek functionality, reliability, efficiency, maintainability, usability, dan portability. Hasil penelitian menunjukkan bahwa aplikasi penilaian e-learning SMK berdasarkan ISO 19796-1 telah berhasil dikembangkan menggunakan metode Software Development Life Cycle (SDLC dengan model waterfall. Selanjutnya hasil dari analisis kualitas aplikasi menggunakan standar ISO 9126 menunjukkan bahwa aplikasi mempunyai hasil rata-rata sangat baik dan layak digunakan untuk penilaian kualitas e-learning SMK.

  1. Down-Regulation of Neuregulin1/ErbB4 Signaling in the Hippocampus Is Critical for Learning and Memory.

    Science.gov (United States)

    Tian, Jia; Geng, Fei; Gao, Feng; Chen, Yi-Hua; Liu, Ji-Hong; Wu, Jian-Lin; Lan, Yu-Jie; Zeng, Yuan-Ning; Li, Xiao-Wen; Yang, Jian-Ming; Gao, Tian-Ming

    2017-08-01

    Hippocampal function is important for learning and memory, and dysfunction of the hippocampus has been linked to the pathophysiology of neuropsychiatric diseases such as schizophrenia. Neuregulin1 (NRG1) and ErbB4, two susceptibility genes for schizophrenia, reportedly modulate long-term potentiation (LTP) at hippocampal Schaffer collateral (SC)-CA1 synapses. However, little is known regarding the contribution of hippocampal NRG1/ErbB4 signaling to learning and memory function. Here, quantitative real-time PCR and Western blotting were used to assess the mRNA and protein levels of NRG1 and ErbB4. Pharmacological and genetic approaches were used to manipulate NRG1/ErbB4 signaling, following which learning and memory behaviors were evaluated using the Morris water maze, Y-maze test, and the novel object recognition test. Spatial learning was found to reduce hippocampal NRG1 and ErbB4 expression. The blockade of NRG1/ErbB4 signaling in hippocampal CA1, either by neutralizing endogenous NRG1 or inhibiting/ablating ErbB4 receptor activity, enhanced hippocampus-dependent spatial learning, spatial working memory, and novel object recognition memory. Accordingly, administration of exogenous NRG1 impaired those functions. More importantly, the specific ablation of ErbB4 in parvalbumin interneurons also improved learning and memory performance. The manipulation of NRG1/ErbB4 signaling in the present study revealed that NRG1/ErbB4 activity in the hippocampus is critical for learning and memory. These findings might provide novel insights on the pathophysiological mechanisms of schizophrenia and a new target for the treatment of Alzheimer's disease, which is characterized by a progressive decline in cognitive function.

  2. Interactive learning media based on flash for basic electronic engineering development for SMK Negeri 1 Driyorejo - Gresik

    Science.gov (United States)

    Mandigo Anggana Raras, Gustav

    2018-04-01

    This research aims to produce a product in the form of flash based interactive learning media on a basic electronic engineering subject that reliable to be used and to know students’ responses about the media. The target of this research is X-TEI 1 class at SMK Negeri 1 Driyorejo – Gresik. The method used in this study is R&D that has been limited into seven stages only (1) potential and problems, (2) data collection, (3) product design, (4) product validation, (5) product revision, (6) field test, and (7) analysis and writing. The obtained result is interactive learning media named MELDASH. Validation process used to produce a valid interactive learning media. The result of media validation state that the interactive learning media has a 90.83% rating. Students’ responses to this interactive learning media is really good with 88.89% rating.

  3. Learning stage-dependent effect of M1 disruption on value-based motor decisions.

    Science.gov (United States)

    Derosiere, Gerard; Vassiliadis, Pierre; Demaret, Sophie; Zénon, Alexandre; Duque, Julie

    2017-11-15

    The present study aimed at characterizing the impact of M1 disruption on the implementation of implicit value information in motor decisions, at both early stages (during reinforcement learning) and late stages (after consolidation) of action value encoding. Fifty subjects performed, over three consecutive days, a task that required them to select between two finger responses according to the color (instruction) and to the shape (implicit, undisclosed rule) of an imperative signal: considering the implicit rule in addition to the instruction allowed subjects to earn more money. We investigated the functional contribution of M1 to the implementation of the implicit rule in subjects' motor decisions. Continuous theta burst stimulation (cTBS) was applied over M1 either on Day 1 or on Day 3, producing a temporary lesion either during reinforcement learning (cTBS Learning group) or after consolidation of the implicit rule, during decision-making (cTBS Decision group), respectively. Interestingly, disrupting M1 activity on Day 1 improved the reliance on the implicit rule, plausibly because M1 cTBS increased dopamine release in the putamen in an indirect way. This finding corroborates the view that cTBS may affect activity in unstimulated areas, such as the basal ganglia. Notably, this effect was short-lasting; it did not persist overnight, suggesting that the functional integrity of M1 during learning is a prerequisite for the consolidation of implicit value information to occur. Besides, cTBS over M1 did not impact the use of the implicit rule when applied on Day 3, although it did so when applied on Day 2 in a recent study where the reliance on the implicit rule declined following cTBS (Derosiere et al., 2017). Overall, these findings indicate that the human M1 is functionally involved in the consolidation and implementation of implicit value information underlying motor decisions. However, M1 contribution seems to vanish as subjects become more experienced in using

  4. Role of σ1 Receptors in Learning and Memory and Alzheimer's Disease-Type Dementia.

    Science.gov (United States)

    Maurice, Tangui; Goguadze, Nino

    2017-01-01

    The present chapter will review the role of σ 1 receptor in learning and memory and neuroprotection , against Alzheimer's type dementia. σ 1 Receptor agonists have been tested in a variety of pharmacological and pathological models of learning impairments in rodents these last past 20 years. Their anti-amnesic effects have been explained by the wide-range modulatory role of σ 1 receptors on Ca 2+ mobilizations, neurotransmitter responses, and particularly glutamate and acetylcholine systems, and neurotrophic factors. Recent observations from genetic and pharmacological studies have shown that σ 1 receptor can also be targeted in neurodegenerative diseases, and particularly Alzheimer's disease . Several compounds, acting partly through the σ 1 receptor, have showed effective neuroprotection in transgenic mouse models of Alzheimer's disease . We will review the data and discuss the possible mechanisms of action, particularly focusing on oxidative stress and mitochondrial integrity, trophic factors and a novel hypothesis suggesting a functional interaction between the σ 1 receptor and α 7 nicotinic acetylcholine receptor. Finally, we will discuss the pharmacological peculiarities of non-selective σ 1 receptor ligands, now developed as neuroprotectants in Alzheimer's disease , and positive modulators, recently described and that showed efficacy against learning and memory deficits.

  5. Effect of Non-specific HCN1 Blocker CsCl on Spatial Learning and Memory in Mouse

    Institute of Scientific and Technical Information of China (English)

    YU Xin; GUO Lianjun; YIN Guangfu; ZONG Xiangang; AI Yongxun

    2006-01-01

    It has been suggested that HCN1 is primarily expressed in hippocampus, however little is known about its effects on spatial learning and memory. In the present study, we investigated the effects of non-specific HCN1 blocker CsCl on spatial learning and memory by using Morris water maze and in situ hybridization in mice. The results showed CsCl 160 mg/kg ip for 4 days, and the mean escape latency was 34 s longer than that of normal control (P<0.01). In hippocampal tissues, staining for the HCN1 mRNA was stronger in the DG and CA1 region of the hippocampus (P <0.05, P<0.05, when CsCl-administration group was compared with normal group). Our results suggested that CsCl could significantly affect the spatial learning and memory in mice, and HCN channel is involved in the process of learning and memory.

  6. Language Learning Actions in Two 1x1 Secondary Schools in Catalonia: The Case of Online Language Resources

    Science.gov (United States)

    Calvo, Boris Vázquez; Cassany, Daniel

    2016-01-01

    This paper identifies and describes current attitudes towards classroom digitization and digital language learning practices under the umbrella of EduCAT 1x1, the One-Laptop-Per-Child (OLPC or 1x1) initiative in place in Catalonia. We thoroughly analyze practices worked out by six language teachers and twelve Compulsory Secondary Education (CSE)…

  7. Sex differences, learning flexibility, and striatal dopamine D1 and D2 following adolescent drug exposure in rats

    Science.gov (United States)

    Izquierdo, Alicia; Pozos, Hilda; De La Torre, Adrianna; DeShields, Simone; Cevallos, James; Rodriguez, Jonathan; Stolyarova, Alexandra

    2016-01-01

    Corticostriatal circuitry supports flexible reward learning and emotional behavior from the critical neurodevelopmental stage of adolescence through adulthood. It is still poorly understood how prescription drug exposure in adolescence may impact these outcomes in the long-term. We studied adolescent methylphenidate (MPH) and fluoxetine (FLX) exposure in rats and their impact on learning and emotion in adulthood. In Experiment 1, male and female rats were administered MPH, FLX, or saline (SAL), and compared with methamphetamine (mAMPH) treatment beginning in postnatal day (PND) 37. The rats were then tested on discrimination and reversal learning in adulthood. In Experiment 2, animals were administered MPH or SAL also beginning in PND 37 and later tested in adulthood for anxiety levels. In Experiment 3, we analyzed striatal dopamine D1 and D2 receptor expression in adulthood following either extensive learning (after Experiment 1) or more brief emotional measures (after Experiment 2). We found sex differences in discrimination learning and attenuated reversal learning after MPH and only sex differences in adulthood anxiety. In learners, there was enhanced striatal D1, but not D2, after either adolescent MPH or mAMPH. Lastly, also in learners, there was a sex x treatment group interaction for D2, but not D1, driven by the MPH-pretreated females, who expressed significantly higher D2 levels compared to SAL. These results show enduring effects of adolescent MPH on reversal learning in rats. Developmental psychostimulant exposure may interact with learning to enhance D1 expression in adulthood, and affect D2 expression in a sex-dependent manner. PMID:27091300

  8. Language Learning Strategies used by Students learning Kiswahili1 ...

    African Journals Online (AJOL)

    Success in learning a second language nevertheless an African language has proven a tremendous effort on the part of foreign adult learners enrolled in universities. Motivation and attitude as well as the strategies used by the learners themselves play an important role. However, the greatest challenge for this group of ...

  9. "Learning" Can Improve the Blood Glucose Control Performance for Type 1 Diabetes Mellitus.

    Science.gov (United States)

    Wang, Youqing; Zhang, Jinping; Zeng, Fanmao; Wang, Na; Chen, Xiaoping; Zhang, Bo; Zhao, Dong; Yang, Wenying; Cobelli, Claudio

    2017-01-01

    A learning-type artificial pancreas has been proposed to exploit the repetitive nature in the blood glucose dynamics. We clinically evaluated the efficacy of the learning-type artificial pancreas. We conducted a pilot clinical study in 10 participants of mean age 36.1 years (standard deviation [SD] 12.7; range 16-58) with type 1 diabetes. Each trial was conducted for eight consecutive mornings. The first two mornings were open-loop to obtain the individualized parameters. Then, the following six mornings were closed-loop, during which a learning-type model predictive control algorithm was employed to calculate the insulin infusion rate. To evaluate the algorithm's robustness, each participant took exercise or consumed alcohol on the fourth or sixth closed-loop day and the order was determined randomly. The primary outcome was the percentage of time spent in the target glucose range of 3.9-8.0 mmol/L between 0900 and 1200 h. The percentage of time with glucose spent in target range was significantly improved from 51.6% on day 1 to 71.6% on day 3 (mean difference between groups 17.9%, confidence interval [95% CI] 3.6-32.1; P = 0.020). There were no hypoglycemic episodes developed on day 3 compared with two episodes on day 1. There was no difference in the percentage of time with glucose spent in target range between exercise day versus day 5 and alcohol day versus day 5. The learning-type artificial pancreas system achieved good glycemic regulation and provided increased effectiveness over time. It showed a satisfactory performance even when the blood glucose was challenged by exercise or alcohol.

  10. Caracterização química e determinação dos estádios fenológicos de variedades de videiras cultivadas no Norte Fluminense Chemical characterization and phenological determination of grapes cultivated in the North area of Rio de Janeiro state

    Directory of Open Access Journals (Sweden)

    Felipe Cavalcanti Carneiro da Silva

    2008-03-01

    Full Text Available O experimento foi conduzido no município de Campos dos Goytacazes- RJ, durante os anos de 2005 e 2006, com o intuito de proceder a uma caracterização química e fenológica de variedades de videira cultivadas na região Norte Fluminense. Utilizou-se de plantas das variedades: Romana, Isabel, Kyoho, Moscatel de Hamburgo, Roberta e Niágara Rosada. Para a determinação do clico fenológico das seis variedades, realizaram-se podas em 20-03-2005 e 15-02-006. Para a poda realizada em fevereiro, verificou-se redução do período de poda à colheita em todas as variedades, sendo a variedade Isabel a mais tardia, com ciclo médio de 124 dias para os dois anos.The experiment was carried out in Campos dos Goytacazes County, RJ, in 2005 and 2006, aiming to characterize chemically and phenologically different grapes varieties, such as 'Romana', 'Isabel', 'Kyoho', 'Moscatel de Hamburgo', 'Roberta' and 'Niagara Rosada', cultivated in the North of the state of Rio de Janeiro. The six studied varieties were pruned on 03/20/2005 and 02/15/2006 to determine the phenological cycle. Pruning in February evidenced a reduction of the pruning-harvest period in all varieties. 'Isabel' was the latest variety, with a mean cycle of 124 days in both years.

  11. [Effect of 5-HT1A receptors in the hippocampal DG on active avoidance learning in rats].

    Science.gov (United States)

    Jiang, Feng-ze; Lv, Jing; Wang, Dan; Jiang, Hai-ying; Li, Ying-shun; Jin, Qing-hua

    2015-01-01

    To investigate the effects of serotonin (5-HTIA) receptors in the hippocampal dentate gyrus (DG) on active avoidance learning in rats. Totally 36 SD rats were randomly divided into control group, antagonist group and agonist group(n = 12). Active avoidance learning ability of rats was assessed by the shuttle box. The extracellular concentrations of 5-HT in the DG during active avoidance conditioned reflex were measured by microdialysis and high performance liquid chromatography (HPLC) techniques. Then the antagonist (WAY-100635) or agonist (8-OH-DPAT) of the 5-HT1A receptors were microinjected into the DG region, and the active avoidance learning was measured. (1) During the active avoidance learning, the concentration of 5-HT in the hippocampal DG was significantly increased in the extinction but not establishment in the conditioned reflex, which reached 164.90% ± 26.07% (P active avoidance learning. (3) The microinjection of 8-OH-DPAT(an agonist of 5-HT1A receptor) into the DG significantly facilitated the establishment process and inhibited the extinction process during active avoidance conditioned reflex. The data suggest that activation of 5-HT1A receptors in hipocampal DG may facilitate active avoidance learning and memory in rats.

  12. Manifold optimization-based analysis dictionary learning with an ℓ1∕2-norm regularizer.

    Science.gov (United States)

    Li, Zhenni; Ding, Shuxue; Li, Yujie; Yang, Zuyuan; Xie, Shengli; Chen, Wuhui

    2018-02-01

    Recently there has been increasing attention towards analysis dictionary learning. In analysis dictionary learning, it is an open problem to obtain the strong sparsity-promoting solutions efficiently while simultaneously avoiding the trivial solutions of the dictionary. In this paper, to obtain the strong sparsity-promoting solutions, we employ the ℓ 1∕2 norm as a regularizer. The very recent study on ℓ 1∕2 norm regularization theory in compressive sensing shows that its solutions can give sparser results than using the ℓ 1 norm. We transform a complex nonconvex optimization into a number of one-dimensional minimization problems. Then the closed-form solutions can be obtained efficiently. To avoid trivial solutions, we apply manifold optimization to update the dictionary directly on the manifold satisfying the orthonormality constraint, so that the dictionary can avoid the trivial solutions well while simultaneously capturing the intrinsic properties of the dictionary. The experiments with synthetic and real-world data verify that the proposed algorithm for analysis dictionary learning can not only obtain strong sparsity-promoting solutions efficiently, but also learn more accurate dictionary in terms of dictionary recovery and image processing than the state-of-the-art algorithms. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Learning English Tenses through Spanish Grammar : When Using the L1 Benefits ESL Learning

    OpenAIRE

    López Garrido, Ramon

    2016-01-01

    The current teaching trend of ESL is focused on maximizing the use of the L2 so that the student learns the language through linguistic immersion. This approach leaves the L1 out of the game, even though research has shown it can also be beneficial for the learner. My research intends to demonstrate that translation of English grammar tenses into Spanish can be a helpful way of assimilating English grammar more easily and faster, especially for those students with a poor command of English. ...

  14. APPLICATION OF COOPERATIVE LEARNING MODEL INDEX CARD MATCH TYPE IN IMPROVING STUDENT LEARNING RESULTS ON COMPOSITION AND COMPOSITION FUNCTIONS OF FUNCTIONS INVERS IN MAN 1 MATARAM

    Directory of Open Access Journals (Sweden)

    Syahrir Syahrir

    2017-12-01

    Full Text Available Lack of student response in learning mathematics caused by passive of student in process of learning progress so that student consider mathematics subject is difficult subject to be understood. The research is Classroom Action Research (PTK using 2 cycles, then the purpose of this research is how the implementation of cooperative learning type of index card match in improving student learning outcomes on the subject matter of composition function and inverse function in MAN 1 Mataram. While the results of the analysis in the study showed that there is in cycle I obtained classical completeness 78.79% with the average score of student learning outcomes 69.78 and the average value of student learning responses with the category Enough, then in cycle II shows that classical thoroughness 87 , 89% with mean score of student learning result 78,94 and average value of student learning response with good category. So it can be concluded that the implementation of Model Cooperative Learning Type Index Card Match can improve student learning outcomes on the subject matter of composition function and inverse function.

  15. Learning Science and the Science of Learning. Science Educators' Essay Collection.

    Science.gov (United States)

    Bybee, Rodger W., Ed.

    This yearbook addresses critical issues in science learning and teaching. Contents are divided into four sections: (1) "How Do Students Learn Science?"; (2) "Designing Curriculum for Student Learning"; (3) "Teaching That Enhances Student Learning"; and (4) "Assessing Student Learning." Papers include: (1) "How Students Learn and How Teachers…

  16. ISSR

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-05

    Oct 5, 2009 ... Mediterranean faba bean (Vicia faba L.) with ISSR markers. Field. Crops Res. 108: 39-44. Thimmappaiah WG, Santhosh D, Shobha, Melwyn GS (2008). Assessment of genetic diversity in cashew germplasm using RAPD and ISSR markers. Scientia Horticulturae. 11(022): 1-7. Veerle L, Isabel RR, Els C, De ...

  17. Leaders from Nursing's History.

    Science.gov (United States)

    Fondiller, Shirley H.; And Others

    1995-01-01

    Looks at the lives and accomplishments of four leaders in professional nursing: (1) Loretta Ford, who championed the cause of nurse practitioners; (2) Mable Staupers, a pioneer in community health and nursing; (3) Janet Geister, a leader in private nursing; and (4) Isabel Stewart, who led the movement to standardize nursing education. (JOW)

  18. Sensorimotor learning in Dab1(scm) (scrambler) mutant mice.

    Science.gov (United States)

    Lalonde, R; Strazielle, C

    2011-04-15

    Homozygous Dab1(scm) mouse mutants with cell ectopias in cerebellar cortex and neocortex were compared with non-ataxic controls on two tests of motor coordination: rotorod and grid climbing. Even at the minimal speed of 4 rpm and unlike controls, none of the Dab1(scm) mutants reached criterion on the constant speed rotorod. In contrast, Dab1(scm) mutants improved their performances on the vertical grid over the course of the same number of trials. Thus, despite massive cerebellar degeneration, sensorimotor learning for equilibrium is still possible, indicating the potential usefulness of the grid-climbing test in determining residual functions in mice with massive cerebellar damage. Copyright © 2010. Published by Elsevier B.V.

  19. Neurofeedback of SMR and Beta1 Frequencies: An Investigation of Learning Indices and Frequency-Specific Effects.

    Science.gov (United States)

    Pimenta, Miguel G; van Run, Chris; de Fockert, Jan W; Gruzelier, John H

    2018-05-15

    Despite evidence that Sensorimotor Rhythm (SMR) and beta1 neurofeedback have distinct cognitive enhancement effects, it remains unclear whether their amplitudes can be independently enhanced. Furthermore, demands for top-down attention control, postural restraint and maintenance of cognitive set processes, all requiring low-beta frequencies, might masquerade as learning and confound interpretation. The feasibility of selectively enhancing SMR and beta1 amplitudes was investigated with the addition of a random frequency control condition that also requires the potentially confounding cognitive processes. A comprehensive approach to assessing neurofeedback learning was undertaken through the calculation of learning indices within- and across-session and pre-to-post baseline. Herein we provide the first demonstration of beta1 within-session amplitude learning that was not attributable to extraneous cognitive processes, for it was not found with random frequency training. On the other hand, within-session SMR learning might have been obscured by high interindividual variability and methodological limitations such as the type of feedback screen, the insufficient number of sessions, and the exclusion of simultaneous theta and high-beta inhibition. Interestingly, SMR and beta1 amplitude increased across sessions in the three groups suggesting unspecific effects of neurofeedback in the low beta frequency band. Moreover, there was no clear evidence of frequency specificity associated with either SMR or beta1 training. Some methodological limitations may underpin the divergent results with previous studies. Copyright © 2017 IBRO. All rights reserved.

  20. Illustrating performance indicators and course characteristics to support students' self-regulated learning in CS1

    Science.gov (United States)

    Ott, Claudia; Robins, Anthony; Haden, Patricia; Shephard, Kerry

    2015-04-01

    In higher education, quality feedback for students is regarded as one of the main contributors to improve student learning. Feedback to support students' development into self-regulated learners, who set their own goals, self-monitor their actual performance according to these goals, and adjust learning strategies if necessary, is seen as an important aspect of contemporary feedback practice. However, only those students who are aware of the course demands and the impact of certain study behaviors on their final achievement are in a position to self-regulate their learning on an informed basis. Learning analytics is an emerging field primarily concerned with using predictive models to inform educational instructors or learners about projected study outcomes. In a scoping study, over 200 students of an introductory programming course (CS1) were supplied with information revealing performance indicators for different stages on the course and projecting final performance for various achievement levels. The study was set out to explore the impact of this type of feedback in the confined context of a CS1 course as well as to learn about students' attitudes toward diagnostic course data in general. The results from the study suggest that students valued the information, but, despite high engagement with the information, students' study behavior and learning outcome remained rather unaffected for the aspects investigated. Given these multi-layered results, we suggest further exploration on the provision of feedback based on diagnostic course data - a vital step toward more transparency for students to foster their active role in the learning process.

  1. 77 FR 50376 - Drawbridge Operation Regulation, Atlantic Intracoastal Waterway (AIWW); Wrightsville Beach, NC...

    Science.gov (United States)

    2012-08-21

    ... duration that the moveable bridges will be maintained in the closed position. The races have been reserved... of Transportation (NCDOT) bridges: The S.R. 74 Bridge, across the AIWW, mile 283.1 at Wrightsville Beach, NC; the Cape Fear Memorial Bridge across the Cape Fear River, mile 26.8; and the Isabel S. Holmes...

  2. Launch of new e-learning course “Safety during LS1

    CERN Multimedia

    HSE Unit

    2013-01-01

    After 3 years of activity, the LHC and the rest of the accelerator chain have been shut down for about 2 years (from February 2013 to December 2014) due to maintenance and upgrade work, on the surface as well as underground.   CERN has developed a new e-learning course related to this Long Shutdown period (LS1) so as to provide all the collaborators working in the LS1 area with accurate security-oriented information. The objectives of this new course are to: Present LS1 and its context, Identify CERN facilities’ major risks, Identify the main risks associated with our co-activities, Explain how safety issues are being handled at CERN, Present all the basic safety measures to be respected, Present all emergency and rescue instructions. The course is available via the e-learning SIR application. It is compulsory for all newcomers at CERN, along with the “CERN Safety Introduction” training. It is also highly recommended that people who were already w...

  3. Impaired associative fear learning in mice with complete loss or haploinsufficiency of AMPA GluR1 receptors

    Directory of Open Access Journals (Sweden)

    Michael Feyder

    2007-12-01

    Full Text Available There is compelling evidence that L-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA glutamate receptors containing the GluR1 subunit contribute to the molecular mechanisms associated with learning. AMPA GluR1 glutamate receptor knockout mice (KO exhibit abnormal hippocampal and amygdala plasticity, and deficits on various assays for cognition including Pavlovian fear conditioning. Here we examined associative fear learning in mice with complete absence (KO or partial loss (heterozygous mutant, HET of GluR1 on multiple fear conditioning paradigms. After multi-trial delay or trace conditioning, KO displayed impaired tone and context fear recall relative to WT, whereas HET were normal. After one-trial delay conditioning, both KO and HET showed impaired tone and context recall. HET and KO showed normal nociceptive sensitivity in the hot plate and tail flick tests. These data demonstrate that the complete absence of GluR1 subunit-containing receptors prevents the formation of associative fear memories, while GluR1 haploinsufficiency is sufficient to impair one-trial fear learning. These findings support growing evidence of a major role for GluR1-containing AMPA receptors in amygdalamediated forms of learning and memory.

  4. [Optogenetic activation of dorsal hippocampal astrocytic Rac1 blocks the learning of associative memory].

    Science.gov (United States)

    Guo, Xiao-Mu; Liao, Zhao-Hui; Tao, Ye-Zheng; Wang, Fei-Fei; Ma, Lan

    2017-06-25

    Rac1 belongs to the family of Rho GTPases, and plays important roles in the brain function. It affects the cell migration and axon guidance via regulating the cytoskeleton and cellular morphology. However, the effect of its dynamic activation in regulating physiological function remains unclear. Recently, a photoactivatable analogue of Rac1 (PA-Rac1) has been developed, allowing the activation of Rac1 by the specific wavelength of light in living cells. Thus, we constructed recombinant adeno-associated virus (AAV) of PA-Rac1 and its light-insensitive mutant PA-Rac1-C450A under the control of the mouse glial fibrillary acidic protein (mGFAP) promoter to manipulate Rac1 activity in astrocytes by optical stimulation. Primary culture of hippocampal astrocytes was infected with the recombinant AAV-PA-Rac1 or AAV-PA-Rac1-C450A. Real-time fluorescence imaging showed that the cell membrane of the astrocyte expressing PA-Rac1 protruded near the light spot, while the astrocyte expressing PA-Rac1-C450A did not. We injected AAV-PA-Rac1 and AAV-PA-Rac1-C450A into dorsal hippocampus to investigate the role of the activation of Rac1 in regulating the associative learning. With optical stimulation, the PA-Rac1 group, rather than the PA-Rac1-C450A group, showed slower learning curve during the fear conditioning compared with the control group, indicating that activating astrocytic Rac1 blocks the formation of contextual memory. Our data suggest that the activation of Rac1 in dorsal hippocampal astrocyte plays an important role in the associative learning.

  5. Motor skill learning and offline-changes in TGA patients with acute hippocampal CA1 lesions.

    Science.gov (United States)

    Döhring, Juliane; Stoldt, Anne; Witt, Karsten; Schönfeld, Robby; Deuschl, Günther; Born, Jan; Bartsch, Thorsten

    2017-04-01

    Learning and the formation of memory are reflected in various memory systems in the human brain such as the hippocampus based declarative memory system and the striatum-cortex based system involved in motor sequence learning. It is a matter of debate how both memory systems interact in humans during learning and consolidation and how this interaction is influenced by sleep. We studied the effect of an acute dysfunction of hippocampal CA1 neurons on the acquisition (on-line condition) and off-line changes of a motor skill in patients with a transient global amnesia (TGA). Sixteen patients (68 ± 4.4 yrs) were studied in the acute phase and during follow-up using a declarative and procedural test, and were compared to controls. Acute TGA patients displayed profound deficits in all declarative memory functions. During the acute amnestic phase, patients were able to acquire the motor skill task reflected by increasing finger tapping speed across the on-line condition, albeit to a lesser degree than during follow-up or compared to controls. Retrieval two days later indicated a greater off-line gain in motor speed in patients than controls. Moreover, this gain in motor skill performance was negatively correlated to the declarative learning deficit. Our results suggest a differential interaction between procedural and declarative memory systems during acquisition and consolidation of motor sequences in older humans. During acquisition, hippocampal dysfunction attenuates fast learning and thus unmasks the slow and rigid learning curve of striatum-based procedural learning. The stronger gains in the post-consolidation condition in motor skill in CA1 lesioned patients indicate a facilitated consolidation process probably occurring during sleep, and suggest a competitive interaction between the memory systems. These findings might be a reflection of network reorganization and plasticity in older humans and in the presence of CA1 hippocampal pathology. Copyright © 2016

  6. Epilepsy and Learning Disabilities: Part 1--Diagnosing and Solving School Learning Disabilities in Epilepsy

    Science.gov (United States)

    Mittan, Robert J.

    2010-01-01

    This is a six part article intended to give parents the information and strategies they need to cope with their child with epilepsy who may have school learning problems. Epilepsy and seizures affect the classroom in unique ways that can make the learning experience especially challenging for some kids. Fortunately, much can be done to give the…

  7. Effectiveness Of Education To Improve Ability Game For Children Learning Difficulties Additive (Study Case at SDN 1 Lamongan

    Directory of Open Access Journals (Sweden)

    Nisaul Barokati

    2015-03-01

    Full Text Available This research is motivated by the child's learning disabilities who cannot do the sums 1-20. From roommates Researchers Gave test, the child cannot do the sums 1-20. This study aims to Prove the effectiveness of educational games for kids summation improves learning disabilities. Type of research is the Single Subject Research, with ABA design and the data analysis techniques using visual analysis chart. Measurement variables using a percentage of the number of questions answered the Correctly. From the results of this study indicate that effective educational games to Enhance the abilities of the sum of numbers for child learning disabilities in SDN 1 Lamongan So that educational games can be used as one solution to help improve the child's ability to sum numbers learning disabilities

  8. La enseñanza de la Geografía en el Instituto-Escuela. // The teaching of geography in Instituto-Escuela

    Directory of Open Access Journals (Sweden)

    Enrique Arjona Gallego

    2013-06-01

    Full Text Available (ES La experiencia que presentamos es una aplicación didáctica del patrimonio histórico del Instituto-Escuela (1918-1936, conservado en el Instituto “Isabel la Católica”. La realizamos con nuestros alumnos de 4º de ESO a lo largo del curso 2012-2013 con dos objetivos: que conocieran las innovaciones educativas del Instituto-Escuela, y en concreto cómo se enseñaba en él la Geografía, e iniciarlos en la investigación histórica. Para llevar a cabo su trabajo, nuestros alumnos utilizaron los cuadernos de clase del antiguo alumnado del Instituto-Escuela, analizando sus contenidos y la metodología empleada por los profesores para el aprendizaje de la Geografía. // (EN The experience we are presenting is a didactic application of the historical heritage of the Instituto-Escuela (1918-1936, preserved at the Institute “Isabel La Católica”. We did it with our students of 4th year of Secondary Education along the year 2012-2013. The experience had two objectives: they knew the educational innovations in the school and to be more precise how geography was taught in it and to introduce to historical research. To carry out their work, our students used notebooks from former students of the school, by analyzing their contents and the methodology used to learn geography by teachers.

  9. Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning.

    Science.gov (United States)

    Anastasaki, Corina; Woo, Albert S; Messiaen, Ludwine M; Gutmann, David H

    2015-06-15

    Neurofibromatosis type 1 (NF1) is a common autosomal dominant neurologic condition characterized by significant clinical heterogeneity, ranging from malignant cancers to cognitive deficits. Recent studies have begun to reveal rare genotype-phenotype correlations, suggesting that the specific germline NF1 gene mutation may be one factor underlying disease heterogeneity. The purpose of this study was to define the impact of the germline NF1 gene mutation on brain neurofibromin function relevant to learning. Herein, we employ human NF1-patient primary skin fibroblasts, induced pluripotent stem cells and derivative neural progenitor cells (NPCs) to demonstrate that NF1 germline mutations have dramatic effects on neurofibromin expression. Moreover, while all NF1-patient NPCs exhibit increased RAS activation and reduced cyclic AMP generation, there was a neurofibromin dose-dependent reduction in dopamine (DA) levels. Additionally, we leveraged two complementary Nf1 genetically-engineered mouse strains in which hippocampal-based learning and memory is DA-dependent to establish that neuronal DA levels and signaling as well as mouse spatial learning are controlled in an Nf1 gene dose-dependent manner. Collectively, this is the first demonstration that different germline NF1 gene mutations differentially dictate neurofibromin function in the brain. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. Differentiation of Forebrain and Hippocampal Dopamine 1-Class Receptors, D1R and D5R, in Spatial Learning and Memory

    Science.gov (United States)

    Sariñana, Joshua; Tonegawa, Susumu

    2017-01-01

    Activation of prefrontal cortical (PFC), striatal, and hippocampal dopamine 1-class receptors (D1R and D5R) is necessary for normal spatial information processing. Yet the precise role of the D1R versus the D5R in the aforementioned structures, and their specific contribution to the water-maze spatial learning task remains unknown. D1R- and D5R- specific in situ hybridization probes showed that forebrain restricted D1R and D5R KO mice (F-D1R/D5R KO) displayed D1R mRNA deletion in the medial (m)PFC, dorsal and ventral striatum, and the dentate gyrus (DG) of the hippocampus. D5R mRNA deletion was limited to the mPFC, the CA1 and DG hippocampal subregions. F-D1R/D5R KO mice were given water-maze training and displayed subtle spatial latency differences between genotypes and spatial memory deficits during both regular and reversal training. To differentiate forebrain D1R from D5R activation, forebrain restricted D1R KO (F-D1R KO) and D5R KO (F-D5R KO) mice were trained on the water-maze task. F-D1R KO animals exhibited escape latency deficits throughout regular and reversal training as well as spatial memory deficits during reversal training. F-D1R KO mice also showed perseverative behavior during the reversal spatial memory probe test. In contrast, F-D5R KO animals did not present observable deficits on the water-maze task. Because F-D1R KO mice showed water-maze deficits we tested the necessity of hippocampal D1R activation for spatial learning and memory. We trained DG restricted D1R KO (DG-D1R KO) mice on the water-maze task. DG-D1R KO mice did not present detectable spatial memory deficit, but did show subtle deficits during specific days of training. Our data provides evidence that forebrain D5R activation plays a unique role in spatial learning and memory in conjunction with D1R activation. Moreover, these data suggest that mPFC and striatal, but not DG D1R activation are essential for spatial learning and memory. PMID:26174222

  11. Experimentally-induced learned helplessness in adolescents with type 1 diabetes.

    Science.gov (United States)

    McLaughlin, Elizabeth; Lefaivre, Marie-josée; Cummings, Elizabeth

    2010-05-01

    To determine whether adolescents with type 1 diabetes are more at risk for learned helplessness than their healthy peers. Twenty-three adolescents with diabetes and 25 controls completed a solvable or unsolvable concept formation task. All completed pre- and post-task performance and attribution ratings, and later completed an anagram-solving task to determine if perceived helplessness on the first task would negatively impact performance on the second. Participants in the unsolvable condition solved fewer anagrams; those with diabetes did not show weaker performance than controls. Participants in the solvable condition (diabetes and controls) showed an increase in internal attributions from before the concept formation task to after. In the unsolvable condition, only participants with diabetes made more external attributions for their failure. Contrary to the only other controlled study to use this paradigm in youth with chronic illness, adolescents with diabetes were not more susceptible to learned helplessness.

  12. E-learning in Type 1 Medical Universities of Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Bagher ROKNI

    2005-07-01

    Full Text Available ABSTRACT Nowadays the Internet is the technological pedestal of organization in the information society and one of the main applications that the Internet offers is the Digital Library (DL. Each society, especially those that claim training of the public, predictably need implementation and endorsement these systems. The time of chalk and board is passed and the globalization and universal village demands a movement targeting to establish an information society. The university is said to be responsible for making "Human". In the era of information explosion, how can a university rely on a physical classroom, a tired teacher and some drowsy students listening to him? Internet "the sweet invention of man" is a bridge, between "slump" and "spurt". It is up to each authority in a university to design, employ, develop and evaluate a system embracing Internet, Multimedia, Network and so on to go parallel in modern era and to introduce the supreme system of E-learning in its program. Of different aspects of E-learning including computer networks, multimedia, search engines, electronic libraries, distance learning, and all that (Piskurich, 2003, most of the type 1 medical universities of Iran exploit, some how or another, all or some of them. These universities including Tehran, Iran, Shahid Beheshti, Mashhad, Isfahan, Tabriz, Shiraz, Ahwaz, and Kerman, at present encompass a powerful link with their audiences regarding digital libraries, search engine and authentic data bases. The present article is going to have a bird's eye view at various capacities of these universities in this regard.

  13. Browse Author Index

    African Journals Online (AJOL)

    B. Bamford, Jan Katherine · Baptista, Isabel · Bardelle, Carolina · Bastos, Sênia · Beard, Colin · Beqo, Ina · Blain, Matthew · Bolt, Ester Ellen Trees · Bosma, Robert · Bossema, Jan · Budhiastra, I. Made Mahendra · Buijtendijk, Harald 1 - 12 of 12 Items. ISSN: 2224-3534. AJOL African Journals Online. HOW TO USE AJOL.

  14. The Effect of Video-Assisted Inquiry Modified Learning Model on Student’s Achievement on 1st Fundamental Physics Practice

    Directory of Open Access Journals (Sweden)

    T W Maduretno

    2017-12-01

    Full Text Available The purpose of research are: (1 to know the effect of video-assisted inquiry modified learning model on student’s achievement; (2 to improve the student’s achievement in 1st Fundamental Physics Practice through video-assisted inquiry modified learning model. The student’s achievement as dependent variables includes the aspects of knowledge, skill, and attitude. The sampling technique did not choose at random. The Mathematics Education as the control group and the Science Education as the experimental group. The experimental group used video-assisted inquiry modified learning model and the control group used inquiry learning model. The collecting data technique used observation, questionnaire, and test. The researcher used the independent t-test that purposed to compare the average of achievement of control and experiment group. The results of research were: (1 there was an effect of video-assisted inquiry modified learning model on the knowledge and skill aspect but there was not on the attitude aspect; (2 The average of learning outcome of the experimental group higher than the control group’s; (3 The video-assisted inquiry modified learning model helped more skilled and trained student to discovery, inquiry the scientific principle, experiment and observation, and explain the experiment and observation’s result so that the students be able to understand the materials on the 1st Fundamental Physics Practice.

  15. 34 CFR 425.1 - What is the Demonstration Projects for the Integration of Vocational and Academic Learning Program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the Demonstration Projects for the Integration of Vocational and Academic Learning Program? 425.1 Section 425.1 Education Regulations of the Offices... EDUCATION DEMONSTRATION PROJECTS FOR THE INTEGRATION OF VOCATIONAL AND ACADEMIC LEARNING PROGRAM General...

  16. Comparative Study of Learning Using E-Learning and Printed Materials on Independent Learning and Creativity

    Science.gov (United States)

    Wahyu Utami, Niken; Aziz Saefudin, Abdul

    2018-01-01

    This study aims to determine: 1) differences in students taking independent learning by using e-learning and the students who attend the learning by using the print instructional materials ; 2) differences in the creativity of students who follow learning with e-learning and the students who attend the learning by using the print instructional materials ; 3) differences in learning independence and creativity of students attend learning with e-learning and the students who attend lessons using printed teaching materials in the subject of Mathematics Instructional Media Development. This study was a quasi-experimental research design using only posttest control design. The study population was all students who take courses in Learning Mathematics Media Development, Academic Year 2014/2015 100 students and used a random sample (random sampling) is 60 students. To test the hypothesis used multivariate analysis of variance or multivariable analysis of variance (MANOVA) of the track. The results of this study indicate that 1) There is a difference in student learning independence following study using the e-learning and the students who attend lessons using printed teaching materials in the lecture PMPM ( F = 4.177, p = 0.046 0.05) ; No difference learning independence and creativity of students attend learning by using e-learning and the students who attend the learning using printed teaching materials in the lecture PMPM (F = 2.452, p = 0.095 > 0.05). Based on these studies suggested that the learning using e -learning can be used to develop student creativity, while learning to use e -learning and teaching materials can be printed to use to develop students’ independence.

  17. Basic life support: evaluation of learning using simulation and immediate feedback devices1.

    Science.gov (United States)

    Tobase, Lucia; Peres, Heloisa Helena Ciqueto; Tomazini, Edenir Aparecida Sartorelli; Teodoro, Simone Valentim; Ramos, Meire Bruna; Polastri, Thatiane Facholi

    2017-10-30

    to evaluate students' learning in an online course on basic life support with immediate feedback devices, during a simulation of care during cardiorespiratory arrest. a quasi-experimental study, using a before-and-after design. An online course on basic life support was developed and administered to participants, as an educational intervention. Theoretical learning was evaluated by means of a pre- and post-test and, to verify the practice, simulation with immediate feedback devices was used. there were 62 participants, 87% female, 90% in the first and second year of college, with a mean age of 21.47 (standard deviation 2.39). With a 95% confidence level, the mean scores in the pre-test were 6.4 (standard deviation 1.61), and 9.3 in the post-test (standard deviation 0.82, p basic cardiopulmonary resuscitation, according to the feedback device; 43.7 (standard deviation 26.86) mean duration of the compression cycle by second of 20.5 (standard deviation 9.47); number of compressions 167.2 (standard deviation 57.06); depth of compressions of 48.1 millimeter (standard deviation 10.49); volume of ventilation 742.7 (standard deviation 301.12); flow fraction percentage of 40.3 (standard deviation 10.03). the online course contributed to learning of basic life support. In view of the need for technological innovations in teaching and systematization of cardiopulmonary resuscitation, simulation and feedback devices are resources that favor learning and performance awareness in performing the maneuvers.

  18. Facilitating Learning Organizations. Making Learning Count.

    Science.gov (United States)

    Marsick, Victoria J.; Watkins, Karen E.

    This book offers advice to facilitators and change agents who wish to build systems-level learning to create knowledge that can be used to gain a competitive advantage. Chapter 1 describes forces driving companies to build, sustain, and effectively use systems-level learning and presents and links a working definition of the learning organization…

  19. Dissociable Hippocampal and Amygdalar D1-like receptor contribution to Discriminated Pavlovian conditioned approach learning

    Science.gov (United States)

    Andrzejewski, Matthew E; Ryals, Curtis

    2016-01-01

    Pavlovian conditioning is an elementary form of reward-related behavioral adaptation. The mesolimbic dopamine system is widely considered to mediate critical aspects of reward-related learning. For example, initial acquisition of positively-reinforced operant behavior requires dopamine (DA) D1 receptor (D1R) activation in the basolateral amygdala (BLA), central nucleus of the amygdala (CeA), and the ventral subiculum (vSUB). However, the role of D1R activation in these areas on appetitive, non-drug-related, Pavlovian learning is not currently known. In separate experiments, microinfusions of the D1-like receptor antagonist SCH-23390 (3.0 nmol/0.5 μL per side) into the amygdala and subiculum preceded discriminated Pavlovian conditioned approach (dPCA) training sessions. D1-like antagonism in all three structures impaired the acquisition of discriminated approach, but had no effect on performance after conditioning was asymptotic. Moreover, dissociable effects of D1-like antagonism in the three structures on components of discriminated responding were obtained. Lastly, the lack of latent inhibition in drug-treated groups may elucidate the role of D1-like in reward-related Pavlovian conditioning. The present data suggest a role for the D1 receptors in the amygdala and hippocampus in learning the significance of conditional stimuli, but not in the expression of conditional responses. PMID:26632336

  20. A learning skills course for the 1st year medical students: an experience at a Saudi medical school

    Directory of Open Access Journals (Sweden)

    Siddiqui IA

    2015-03-01

    Full Text Available Imran A Siddiqui,1 Khalid A Bin Abdulrahman,2 Mohammed A Alsultan3 1Department of Medical Education and Postgraduate Studies, Saudi Commission for Health Specialties, Riyadh, Saudi Arabia; 2College of Medicine, Al-Imam Muhammad Ibn Saud Islamic University (IMSIU, Riyadh, Saudi Arabia; 3College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia Background: Every year nearly 1,500 students enter into medical program after passing high school and national aptitude exams. However, many students experience frustration, failure, and psychological morbidities like stress, depression, and anxiety because they are not aware of their learning styles or do not have effective learning skills and strategies. The College of Medicine of Al-Imam Muhammad ibn Saud Islamic University has adopted the outcome based, community oriented, Spiral Curriculum. Although the curriculum is innovative, on the other hand, it is very demanding. Objective: The purpose of this paper is to share educational structure and evaluation results of the course on effective learning and study skills for the 1st year medical students. Methods: To prepare our students in order to cope with this demanding but promising curriculum, we conducted an effective and comprehensive learning skills course for 16 weeks in the first semester of year 1 in the medical program. Performance of each student was assessed and the course evaluation was done by students at the end of the course. Results: The attendance of the students throughout the course was over 90%. The average performance of students in the summative assessment was 78% and the course was generally liked by the students. Discussion: Students overall had a positive attitude toward the learning skills course. Majority of the students showed interest in attending the sessions regularly and realized the significance of this course to improve their learning skills. Keywords: medical students, learning

  1. EFFORTS TO IMPROVE LEARNING MOTIVATION OF STUDENT WITH CONTENT MASTERY IN SMP NEGERI 1 METRO

    Directory of Open Access Journals (Sweden)

    Hadi Pranoto

    2013-09-01

    Full Text Available Abstract: The study design using action research applied in guidance and counseling services (follow-services research. Subjects in this study, researchers took VII.4 grade students of SMP Negeri 1 Metro Odd Semester Lesson Tabun 2012/2013. Of the 24 students, there are 10 students who experience a lack of motivation to learn to 41.66%. The method used in collecting data by observation and field notes. Analysis of the data used is the analysis of qualitative and quantitative data. Validity test is done through assessment experts /specialists ie counseling teachers SMP Negeri 1 Metro, other friends peer discussions that instrument with other friends FKIP students with courses in counseling. The results of this study, it can be concluded that the results obtained through the implementation of the procurement of content services in increasing the motivation of learners class VII.4 SMP Negeri 1 Metro Tabun Odd Semester Lesson 20 12/20 13 is visible from the change in behavior and ability of learners in learners become more willing to meet the needs of achievement, students can understand or have confidence in learning, learners have the ability to overcome failure in learning, and learners have a good competitiveness in the service learning. Through mastery of content supplied by BK teacher can increase the motivation of learners class VII.4 SMP Negeri 1 Metro Odd Semester Academic Year 201212013. There is increased the motivation of learners in the first cycle seen from the average percentage that is equal to 27.5% and in the second cycle of 75 %, resulting in an increase of 47.5%. Response and activity VIl.4 grade students of SMP Negeri 1 Metro Odd Semester Lesson Tabun 2012/2013 on the service in the content mastery enhance learning motivation is very positive, it is shown by the participation of learners in the service following the mastery of content, learner motivation and enthusiasm in participating services as well as content mastery

  2. Learning Design Development for Blended Learning

    DEFF Research Database (Denmark)

    Hansen, Janne Saltoft

    Learning design development for blended learning We started implementing Blackboard at Aarhus University in 2013. At the Health Faculty Blackboard replaced AULA which was a LMS with functionality for file distribution and only a vague focus on learning tools. Most teachers therefore had...... no experiences with blended leaning and technology supported out-of-class activities. At the pedagogical unit at the Health faculty we wanted to follow the Blackboard implementation with pedagogical tools for learning design to evolve the pedagogical use of the system. We needed to make development of blended...... learning courses easier for the teachers and also ensure quality in the courses. This poster describes the process from development of the learning design to implementation of the learning design at the faculty: 1. How to place demands on a learning design-model and how to develop and use such a model. 2...

  3. Enhancement of motor learning by focal intermittent theta burst stimulation (iTBS) of either the primary motor (M1) or somatosensory area (S1) in healthy human subjects.

    Science.gov (United States)

    Platz, Thomas; Adler-Wiebe, Marija; Roschka, Sybille; Lotze, Martin

    2018-01-01

    Motor rehabilitation after brain damage relies on motor re-learning as induced by specific training. Non-invasive brain stimulation (NIBS) can alter cortical excitability and thereby has a potential to enhance subsequent training-induced learning. Knowledge about any priming effects of NIBS on motor learning in healthy subjects can help to design targeted therapeutic applications in brain-damaged subjects. To examine whether complex motor learning in healthy subjects can be enhanced by intermittent theta burst stimulation (iTBS) to primary motor or sensory cortical areas. Eighteen young healthy subjects trained eight different arm motor tasks (arm ability training, AAT) once a day for 5 days using their left non-dominant arm. Except for day 1 (baseline), training was performed after applying an excitatory form of repetitive transcranial magnetic stimulation (iTBS) to either (I) right M1 or (II) S1, or (III) sham stimulation to the right M1. Subjects were randomly assigned to conditions I, II, or III. A principal component analysis of the motor behaviour data suggested eight independent motor abilities corresponding to the 8 trained tasks. AAT induced substantial motor learning across abilities with generalisation to a non-trained test of finger dexterity (Nine-Hole-Peg-Test, NHPT). Participants receiving iTBS (to either M1 or S1) showed better performance with the AAT tasks over the period of training compared to sham stimulation as well as a bigger improvement with the generalisation task (NHPT) for the trained left hand after training completion. Priming with an excitatory repetitive transcranial magnetic stimulation as iTBS of either M1 or S1 can enhance motor learning across different sensorimotor abilities.

  4. Does peer learning or higher levels of e-learning improve learning abilities? A randomized controlled trial.

    Science.gov (United States)

    Worm, Bjarne Skjødt; Jensen, Kenneth

    2013-01-01

    Background and aims The fast development of e-learning and social forums demands us to update our understanding of e-learning and peer learning. We aimed to investigate if higher, pre-defined levels of e-learning or social interaction in web forums improved students' learning ability. Methods One hundred and twenty Danish medical students were randomized to six groups all with 20 students (eCases level 1, eCases level 2, eCases level 2+, eTextbook level 1, eTextbook level 2, and eTextbook level 2+). All students participated in a pre-test, Group 1 participated in an interactive case-based e-learning program, while Group 2 was presented with textbook material electronically. The 2+ groups were able to discuss the material between themselves in a web forum. The subject was head injury and associated treatment and observation guidelines in the emergency room. Following the e-learning, all students completed a post-test. Pre- and post-tests both consisted of 25 questions randomly chosen from a pool of 50 different questions. Results All students concluded the study with comparable pre-test results. Students at Level 2 (in both groups) improved statistically significant compared to students at level 1 (p>0.05). There was no statistically significant difference between level 2 and level 2+. However, level 2+ was associated with statistically significant greater student's satisfaction than the rest of the students (p>0.05). Conclusions This study applies a new way of comparing different types of e-learning using a pre-defined level division and the possibility of peer learning. Our findings show that higher levels of e-learning does in fact provide better results when compared with the same type of e-learning at lower levels. While social interaction in web forums increase student satisfaction, learning ability does not seem to change. Both findings are relevant when designing new e-learning materials.

  5. Does peer learning or higher levels of e-learning improve learning abilities? A randomized controlled trial

    Science.gov (United States)

    Worm, Bjarne Skjødt; Jensen, Kenneth

    2013-01-01

    Background and aims The fast development of e-learning and social forums demands us to update our understanding of e-learning and peer learning. We aimed to investigate if higher, pre-defined levels of e-learning or social interaction in web forums improved students’ learning ability. Methods One hundred and twenty Danish medical students were randomized to six groups all with 20 students (eCases level 1, eCases level 2, eCases level 2+, eTextbook level 1, eTextbook level 2, and eTextbook level 2+). All students participated in a pre-test, Group 1 participated in an interactive case-based e-learning program, while Group 2 was presented with textbook material electronically. The 2+ groups were able to discuss the material between themselves in a web forum. The subject was head injury and associated treatment and observation guidelines in the emergency room. Following the e-learning, all students completed a post-test. Pre- and post-tests both consisted of 25 questions randomly chosen from a pool of 50 different questions. Results All students concluded the study with comparable pre-test results. Students at Level 2 (in both groups) improved statistically significant compared to students at level 1 (p>0.05). There was no statistically significant difference between level 2 and level 2+. However, level 2+ was associated with statistically significant greater student's satisfaction than the rest of the students (p>0.05). Conclusions This study applies a new way of comparing different types of e-learning using a pre-defined level division and the possibility of peer learning. Our findings show that higher levels of e-learning does in fact provide better results when compared with the same type of e-learning at lower levels. While social interaction in web forums increase student satisfaction, learning ability does not seem to change. Both findings are relevant when designing new e-learning materials. PMID:24229729

  6. Does peer learning or higher levels of e-learning improve learning abilities? A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Bjarne Skjødt Worm

    2013-11-01

    Full Text Available Background and aims : The fast development of e-learning and social forums demands us to update our understanding of e-learning and peer learning. We aimed to investigate if higher, pre-defined levels of e-learning or social interaction in web forums improved students’ learning ability. Methods : One hundred and twenty Danish medical students were randomized to six groups all with 20 students (eCases level 1, eCases level 2, eCases level 2+, eTextbook level 1, eTextbook level 2, and eTextbook level 2+. All students participated in a pre-test, Group 1 participated in an interactive case-based e-learning program, while Group 2 was presented with textbook material electronically. The 2+ groups were able to discuss the material between themselves in a web forum. The subject was head injury and associated treatment and observation guidelines in the emergency room. Following the e-learning, all students completed a post-test. Pre- and post-tests both consisted of 25 questions randomly chosen from a pool of 50 different questions. Results : All students concluded the study with comparable pre-test results. Students at Level 2 (in both groups improved statistically significant compared to students at level 1 (p>0.05. There was no statistically significant difference between level 2 and level 2+. However, level 2+ was associated with statistically significant greater student's satisfaction than the rest of the students (p>0.05. Conclusions : This study applies a new way of comparing different types of e-learning using a pre-defined level division and the possibility of peer learning. Our findings show that higher levels of e-learning does in fact provide better results when compared with the same type of e-learning at lower levels. While social interaction in web forums increase student satisfaction, learning ability does not seem to change. Both findings are relevant when designing new e-learning materials.

  7. Operational research to inform a sub-national surveillance intervention for malaria elimination in Solomon Islands

    Directory of Open Access Journals (Sweden)

    Atkinson Jo-An

    2012-03-01

    Full Text Available Abstract Background Successful reduction of malaria transmission to very low levels has made Isabel Province, Solomon Islands, a target for early elimination by 2014. High malaria transmission in neighbouring provinces and the potential for local asymptomatic infections to cause malaria resurgence highlights the need for sub-national tailoring of surveillance interventions. This study contributes to a situational analysis of malaria in Isabel Province to inform an appropriate surveillance intervention. Methods A mixed method study was carried out in Isabel Province in late 2009 and early 2010. The quantitative component was a population-based prevalence survey of 8,554 people from 129 villages, which were selected using a spatially stratified sampling approach to achieve uniform geographical coverage of populated areas. Diagnosis was initially based on Giemsa-stained blood slides followed by molecular analysis using polymerase chain reaction (PCR. Local perceptions and practices related to management of fever and treatment-seeking that would impact a surveillance intervention were also explored using qualitative research methods. Results Approximately 33% (8,554/26,221 of the population of Isabel Province participated in the survey. Only one subject was found to be infected with Plasmodium falciparum (Pf (96 parasites/μL using Giemsa-stained blood films, giving a prevalence of 0.01%. PCR analysis detected a further 13 cases, giving an estimated malaria prevalence of 0.51%. There was a wide geographical distribution of infected subjects. None reported having travelled outside Isabel Province in the previous three months suggesting low-level indigenous malaria transmission. The qualitative findings provide warning signs that the current community vigilance approach to surveillance will not be sufficient to achieve elimination. In addition, fever severity is being used by individuals as an indicator for malaria and a trigger for timely treatment

  8. Hard and Soft Skills Enhancement in Entrepreunership Learning for the Twelfth Grade Students of SMK Kartika IV-1 Malang

    Science.gov (United States)

    Ayuningtyas, Lidya Pradina; Djatmika, Ery Tri; Wardana, Ludi Wishnu

    2015-01-01

    The purpose of this study is to describe the following things: (1) contributions of both hard and soft skills in entrepreneurship learning in SMK Kartika IV-1 Malang; (2) how to increase hard and soft skills on entrepreneurship learning in SMK Kartika IV-1 Malang; and (3) the purpose hard and the soft skills. The research findings showed that: (1)…

  9. Learning bridge tool to improve student learning, preceptor training, and faculty teamwork.

    Science.gov (United States)

    Karimi, Reza; Cawley, Pauline; Arendt, Cassandra S

    2011-04-11

    To implement a Learning Bridge tool to improve educational outcomes for pharmacy students as well as for preceptors and faculty members. Pharmacy faculty members collaborated to write 9 case-based assignments that first-year pharmacy (P1) students worked with preceptors to complete while at experiential sites. Students, faculty members, and preceptors were surveyed about their perceptions of the Learning Bridge process. As in our pilot study,(1) the Learning Bridge process promoted student learning. Additionally, the Learning Bridge assignments familiarized preceptors with the school's P1 curriculum and its content. Faculty teamwork also was increased through collaborating on the assignments. The Learning Bridge assignments provided a compelling learning environment and benefited students, preceptors, and faculty members.

  10. Involvement in Learning Revisited: Lessons We Have Learned.

    Science.gov (United States)

    Astin, Alexander W.

    1996-01-01

    Discusses interconnections between the following two national reports: (1) Involvement in Learning; and (2) The Student Learning Imperative. Reviews recent research on student development in order to demonstrate how student affairs professionals can use this information to enhance learning. (SNR)

  11. Exploring the mitochondrial DNA variability of the Amazonian Yanomami.

    Science.gov (United States)

    Varano, Sara; Scorrano, Gabriele; Martínez-Labarga, Cristina; Finocchio, Andrea; Rapone, Cesare; Berti, Andrea; Rickards, Olga

    2016-11-01

    The aim of this study was to explore the mitochondrial variability in the Yanomami population to reconstruct its demographic history and explore its genetic composition in relation to its cultural and linguistic features. A total of 174 human head hair shafts -collected in 1958- belonging to individuals from a Yanomami group living in Santa Isabel, Brazil, were analyzed. Automated extraction of the hairs was performed, and several methods were applied to optimize the analysis of the degraded DNA. The mtDNA hypervariable segments I-II, along with the 9-bp COII-tRNA Lys deletion, were investigated. Using published data from the Yanomami and other Amazonian populations, several statistical analyses were carried out to explore the genetic variability within the study population. Ninety eight percent of the mitochondrial DNA (mtDNA) sequences analyzed belonged to Native American haplogroups, while 2% belonged to African haplogroups. Compared with the Yanomami groups previously studied, the Santa Isabel sample seemed more genetically similar to other Amazonian populations. Among the Yanomami samples studied to date, the Santa Isabel Yanomami show a higher genetic heterogeneity. This could be due to gene flow with non-Yanomami populations, as well as to the introduction of new mitochondrial haplotypes by gold miners. In both cases, the geographic location of Santa Isabel might have made this Yanomami village less isolated than the others, suggesting that the Rio Negro played a central role in increasing its genetic variability. On the whole, the Yanomami were quite genetically diversified, probably mirroring their great linguistic heterogeneity. Am. J. Hum. Biol. 28:846-856, 2016. © 2016Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  12. The Effect of Cooperative Learning Model and Kolb Learning Styles on Learning Result of the Basics of Politics

    Science.gov (United States)

    Sugiharto

    2015-01-01

    The aims of this research were to determine the effect of cooperative learning model and learning styles on learning result. This quasi-experimental study employed a 2x2 treatment by level, involved independent variables, i.e. cooperative learning model and learning styles, and learning result as the dependent variable. Findings signify that: (1)…

  13. Chemical characteristics of grape juices from different cultivar and rootstock combinations

    Directory of Open Access Journals (Sweden)

    Rita de Cássia Mirela Resende Nassur

    2014-07-01

    Full Text Available The objective of this work was to evaluate the influence of different combinations of grape cultivars and rootstocks on chemical characteristics of grape juices. Six treatments were evaluated, consisting of combinations between the Isabel Precoce and BRS Cora grape cultivars and the 'IAC 766', 'IAC 313', and 'IAC 572' rootstocks. Approximately 10 L of juice were obtained per treatment. Analyses of color, total soluble solids content, pH, anthocyanins, total phenolics, total sugars, and quantification and identification of biogenic amines by HPLC were performed. Biogenic amines, such as putrescine, cadaverine, spermidine, and spermine, were found in all evaluated cultivars. By principal component analysis (PCA, treatments can be divided into two groups, according to the cultivar. Juices obtained from 'Isabel Precoce' are characterized by higher levels of total sugar content and soluble solids; however, juices from 'BRS Cora' are positively correlated with phenolic content, anthocyanins, and color and acidity parameters. The differences found by PCA for juices from the Isabel Precoce and BRS Cora cultivars indicate that, regardless of the rootstock used, the most important factor in the chemical characterization of juices is the grape cultivar.

  14. SIRT1 Regulates Cognitive Performance and Ability of Learning and Memory in Diabetic and Nondiabetic Models

    Directory of Open Access Journals (Sweden)

    Yue Cao

    2017-01-01

    Full Text Available Type 2 diabetes mellitus is a complex age-related metabolic disease. Cognitive dysfunction and learning and memory deficits are main characteristics of age-related metabolic diseases in the central nervous system. The underlying mechanisms contributing to cognitive decline are complex, especially cognitive dysfunction associated with type 2 diabetes mellitus. SIRT1, as one of the modulators in insulin resistance, is indispensable for learning and memory. In the present study, deacetylation, oxidative stress, mitochondrial dysfunction, inflammation, microRNA, and tau phosphorylation are considered in the context of mechanism and significance of SIRT1 in learning and memory in diabetic and nondiabetic murine models. In addition, future research directions in this field are discussed, including therapeutic potential of its activator, resveratrol, and application of other compounds in cognitive improvement. Our findings suggest that SIRT1 might be a potential therapeutic target for the treatment of cognitive impairment induced by type 2 diabetes mellitus.

  15. Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients

    Directory of Open Access Journals (Sweden)

    Máximo Zimerman

    2015-10-01

    Interpretations: Collectively, the present results provide evidence that learning of a motor skill is impaired even in clinically intact NF1 patients based, at least partially, on a GABAergic-cortical dysfunctioning as suggested in previous animal work.

  16. Leadership in nursing education: voices from the past.

    Science.gov (United States)

    Gosline, Mary Beth

    2004-01-01

    When education for nurses became a reality, leaders in the emerging profession spoke out early and often for educational improvements to prepare those who would nurse. The writings and speeches of Isabel Hampton Robb, Mary Adelaide Nutting, Lavinia Lloyd Dock, Lillian Wald, and Isabel Maitland Stewart formed the basis for a qualitative study that documents the voices of early nursing leaders who contributed to the development of nursing education as it moved from "training" toward professional education in a university setting. What is documented in the literature is the desire of these women to enhance the professional status of nursing through improvements in its educational system.

  17. Creating Research-Rich Learning Experiences and Quantitative Skills in a 1st Year Earth Systems Course

    Science.gov (United States)

    King, P. L.; Eggins, S.; Jones, S.

    2014-12-01

    We are creating a 1st year Earth Systems course at the Australian National University that is built around research-rich learning experiences and quantitative skills. The course has top students including ≤20% indigenous/foreign students; nonetheless, students' backgrounds in math and science vary considerably posing challenges for learning. We are addressing this issue and aiming to improve knowledge retention and deep learning by changing our teaching approach. In 2013-2014, we modified the weekly course structure to a 1hr lecture; a 2hr workshop with hands-on activities; a 2hr lab; an assessment piece covering all face-to-face activities; and a 1hr tutorial. Our new approach was aimed at: 1) building student confidence with data analysis and quantitative skills through increasingly difficult tasks in science, math, physics, chemistry, climate science and biology; 2) creating effective learning groups using name tags and a classroom with 8-person tiered tables; 3) requiring students to apply new knowledge to new situations in group activities, two 1-day field trips and assessment items; 4) using pre-lab and pre-workshop exercises to promote prior engagement with key concepts; 5) adding open-ended experiments to foster structured 'scientific play' or enquiry and creativity; and 6) aligning the assessment with the learning outcomes and ensuring that it contains authentic and challenging southern hemisphere problems. Students were asked to design their own ocean current experiment in the lab and we were astounded by their ingenuity: they simulated the ocean currents off Antarctica; varied water density to verify an equation; and examined the effect of wind and seafloor topography on currents. To evaluate changes in student learning, we conducted surveys in 2013 and 2014. In 2014, we found higher levels of student engagement with the course: >~80% attendance rates and >~70% satisfaction (20% neutral). The 2014 cohort felt that they were more competent in writing

  18. Preparing Instructional Designers for Game-Based Learning: Part 1

    Science.gov (United States)

    Hirumi, Atsusi; Appelman, Bob; Rieber, Lloyd; Van Eck, Richard

    2010-01-01

    Like many rapidly growing industries, advances in video game technology are far outpacing research on its design and effectiveness. Relatively little is understood about how to apply what we know about teaching and learning to optimize game-based learning. For the most part, instructional designers know little about game development and video game…

  19. Earthquakes in the kindergarten educate for risk mitigation

    Science.gov (United States)

    Mata, Isabel; Rodrigues, Isabel; Matias, Luis

    2016-04-01

    "Earthquakes in the kindergarten educate for risk mitigation" Isabel Rodrigues, Jardim de Infância D. Dinis, Odivelas, Isabel Mata, Secondary School Adelaide Cabette, Odivelas Luis Matias (UL / IDL), Instituto Dom Luiz, Universityof Lisbon, Lisbon, Portugal In Portugal Education for risk is now recognized as a child training component and young learners should develop the right skills in the first years of life. School can have an important role in this process, as a privileged actor in the mobilization of every society, providing and promoting dynamic and educational practices aimed at the wider spectrum of education for citizenship, the adoption of safety behaviours, prevention and adequate management of risk. The Group of Schools Adelaide Cabette in Odivelas is now a set of schools, from Kindergarten to Secondary. Aiming at educating for risk prevention, we developed an experiment with a pre-school class directed to the seismic risk, which was extended to Earth Sciences because it is difficult to teach this topic to the youngest learners, either from Kindergarten or from Primary School, as they haven't learned enough about planet Earth (many don't even know that it is not flat but round like a ball). This experiment involved a working project 1, which was initially developed in one of the classrooms, in kindergarten D. Dinis, and many questions have been asked by the students. The explanation for the students' questions gave origin to a set of experiences developed in the Secondary school. The same class concluded the project in their own classroom. In this project the young learners could have contact with pre-school teachers, secondary and university researchers, thus promoting the sharing of different knowledge, including the scientific linked to the educational one. We would like to share our poster summarizing our experience which we feltwas not only a great challenge, but also a rewarding way to disseminate science to the youngest learners. 1. Keywords

  20. Learning Object Repositories

    Science.gov (United States)

    Lehman, Rosemary

    2007-01-01

    This chapter looks at the development and nature of learning objects, meta-tagging standards and taxonomies, learning object repositories, learning object repository characteristics, and types of learning object repositories, with type examples. (Contains 1 table.)

  1. Tracking Active Learning in the Medical School Curriculum: A Learning-Centered Approach.

    Science.gov (United States)

    McCoy, Lise; Pettit, Robin K; Kellar, Charlyn; Morgan, Christine

    2018-01-01

    Medical education is moving toward active learning during large group lecture sessions. This study investigated the saturation and breadth of active learning techniques implemented in first year medical school large group sessions. Data collection involved retrospective curriculum review and semistructured interviews with 20 faculty. The authors piloted a taxonomy of active learning techniques and mapped learning techniques to attributes of learning-centered instruction. Faculty implemented 25 different active learning techniques over the course of 9 first year courses. Of 646 hours of large group instruction, 476 (74%) involved at least 1 active learning component. The frequency and variety of active learning components integrated throughout the year 1 curriculum reflect faculty familiarity with active learning methods and their support of an active learning culture. This project has sparked reflection on teaching practices and facilitated an evolution from teacher-centered to learning-centered instruction.

  2. An initial model of the computation viewpoint for a spatial data infrastructure

    CSIR Research Space (South Africa)

    Cooper, Antony K

    2007-08-01

    Full Text Available of the 21st International Cartographic Conference, Durban S. Africa, CD-ROM. Delgado T (2005), "Infraestructuras de Datos Espaciales en países de bajo desarrollo económico. Implementación en Cuba", Tesis de doctorado, ITM "José Martí", 143 pp. Groot R..., Landesvermessungsamt Nordrhein-Westfalen, ulrich.dueren@lverma.nrw.de, Jan Hjelmager, Kort & Matrikelstyrelsen, jnh@kms.dk, Michel Huet, International Hydrographic Bureau, pac@ihb.mc, Petr Rapant, VSB-Technical University of Ostrava, petr.rapant@vsb.cz, Abbas...

  3. A Functional Genomic Analysis of NF1-Associated Learning Disabilities

    National Research Council Canada - National Science Library

    Tang, Shao-Jun

    2006-01-01

    Learning disabilities severely deteriorate the life of many NFI patients. However, the pathogenic process for NFI-associated learning disabilities has not been fully understood and an effective therapy is not available...

  4. Manganese-Disrupted Interaction of Dopamine D1 and NMDAR in the Striatum to Injury Learning and Memory Ability of Mice.

    Science.gov (United States)

    Song, Qifan; Deng, Yu; Yang, Xinxin; Bai, Ying; Xu, Bin; Liu, Wei; Zheng, Wenxue; Wang, Can; Zhang, Meng; Xu, Zhaofa

    2016-12-01

    Manganese (Mn) is widely regarded as a neurotoxic heavy metal that causes learning and memory deficits. Recently, it has been proved that the striatum is related to memory and learning ability. However, no previous study focused on the effect of Mn-induced learning and memory deficits on the striatum. This study aims to investigate the probable interaction of dopamine D1 receptor (DR1) and N-methyl-D-aspartate receptor (NMDAR), two cognition-related receptors in the striatum during Mn exposure. Mice are randomly divided into four groups, including control group, 12.5 mg/kg MnCl 2 group, 25 mg/kg MnCl 2 group, and 50 mg/kg MnCl 2 group. The mice receive intraperitoneal injections of 0, 12.5, 25, and 50 mg/kg MnCl 2 once daily for 2 weeks. Then, learning and memory ability, pathological changes, expression, and interaction of DR1 and NMDAR are determined. It has been found that Mn disrupted spatial learning and memory ability of mice by Morris water maze test and the passive avoidance test. Pathological and ultrastructure were injured. Mn decreased the immunohistochemical activities, protein levels, and messenger RNA (mRNA) expression of DR1, NR1, and NR2A. Mn exposure inhibited interaction between DR1 and NMDAR in striatum by double immunofluorescent staining and co-immunoprecipitation. In conclusion, our study illustrated that Mn caused learning and memory dysfunction via injury of striatum and inhibition of interaction between DR1 and NMDAR in striatum.

  5. PRODUTIVIDADE DE CULTIVARES DE UVAS PARA SUCO SOBRE DIFERENTES PORTA-ENXERTOS IAC EM MOCOCA-SP YIELD OF JUICE GRAPE CULTIVARS GRAFTED ON SOME IAC ROOTSTOCKS

    Directory of Open Access Journals (Sweden)

    MAURILO MONTEIRO TERRA

    2001-08-01

    Full Text Available Estimou-se o potencial de produção de uvas das cultivares copa Concord, Isabel e Seibel 2, recomendadas para produção de suco, enxertadas sobre os porta-enxertos IAC 313 'Tropical', 'IAC 571-6', IAC 572 'Jales', e IAC 766 'Campinas', num experimento conduzido, durante seis anos, na Estação Experimental de Mococa (21º28'S, 47º01'W do Instituto Agronômico de Campinas. Para a variedade Concord, as maiores produções médias foram obtidas quando se utilizaram os porta-enxertos 'IAC 313', 'IAC 571-6' e 'IAC 572', totalizando 3,86kg/planta, 3,81kg/planta e 3,65kg/planta, respectivamente; para 'Isabel', quando se empregaram os porta-enxertos 'IAC 572', 'IAC 571-6' e 'IAC 313', somando 3,85kg/planta, 3,63kg/planta e 3,26kg/planta; para o cv. Seibel 2, quando se fez uso dos porta-enxertos 'IAC 313', 'IAC 572' e 'IAC 571-6', auferiram-se 2,61kg/planta, 2,40kg/planta e 2,10kg/planta; por outro lado, para as três variedades, o porta-enxerto de pior performance foi o 'IAC 766'. Quanto ao vigor, representado pela massa dos ramos podados ao longo dos anos, os melhores porta-enxertos para 'Concord' foram 'IAC 572' e 'IAC 313'; para 'Isabel': 'IAC 766' e 'IAC 313'; e para 'Seibel 2': 'IAC 766' e 'IAC 572'.The yield potential of juice grape cultivars, namely Concord, Isabel and Seibel 2, grafted on 'IAC 313', 'IAC 571-6', 'IAC 572' and 'IAC 766' rootstocks was studied in an experiment conducted for six years at Mococa Experimental Station (21º28'S, 47º01'W. Regarding Concord cultivar, the greatest mean yields were achieved when grafted on 'IAC 313', 'IAC 571-6' and 'IAC 572'rootstocks, respectively 3.86kg/plant, 3.81 kg/plant and 3.65 kg/plant. 'Isabel' gave the largest grape productions when grafted on 'IAC 572' (3.85kg/plant, 'IAC 571-6' (3.63kg/plant and 'IAC 313' (3.26kg/plant. The best grape yields of 'Seibel-2' were obtained when it was grafted on 'IAC 313', 'IAC 572' and 'IAC 571-6', being respectively 2.61kg/plant, 2.40 kg/plant and 2.10 kg

  6. Judgments of Learning in Collaborative Learning Environments

    NARCIS (Netherlands)

    Helsdingen, Anne

    2010-01-01

    Helsdingen, A. S. (2010, March). Judgments of Learning in Collaborative Learning Environments. Poster presented at the 1st International Air Transport and Operations Symposium (ATOS 2010), Delft, The Netherlands: Delft University of Technology.

  7. Opposite monosynaptic scaling of BLP-vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory.

    Science.gov (United States)

    Yang, Ying; Wang, Zhi-Hao; Jin, Sen; Gao, Di; Liu, Nan; Chen, Shan-Ping; Zhang, Sinan; Liu, Qing; Liu, Enjie; Wang, Xin; Liang, Xiao; Wei, Pengfei; Li, Xiaoguang; Li, Yin; Yue, Chenyu; Li, Hong-Lian; Wang, Ya-Li; Wang, Qun; Ke, Dan; Xie, Qingguo; Xu, Fuqiang; Wang, Liping; Wang, Jian-Zhi

    2016-07-14

    Different emotional states lead to distinct behavioural consequences even when faced with the same challenging events. Emotions affect learning and memory capacities, but the underlying neurobiological mechanisms remain elusive. Here we establish models of learned helplessness (LHL) and learned hopefulness (LHF) by exposing animals to inescapable foot shocks or with anticipated avoidance trainings. The LHF animals show spatial memory potentiation with excitatory monosynaptic upscaling between posterior basolateral amygdale (BLP) and ventral hippocampal CA1 (vCA1), whereas the LHL show memory deficits with an attenuated BLP-vCA1 connection. Optogenetic disruption of BLP-vCA1 inputs abolishes the effects of LHF and impairs synaptic plasticity. By contrast, targeted BLP-vCA1 stimulation rescues the LHL-induced memory deficits and mimics the effects of LHF. BLP-vCA1 stimulation increases synaptic transmission and dendritic plasticity with the upregulation of CREB and intrasynaptic AMPA receptors in CA1. These findings indicate that opposite excitatory monosynaptic scaling of BLP-vCA1 controls LHF- and LHL-modulated spatial memory, revealing circuit-specific mechanisms linking emotions to memory.

  8. Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

    Science.gov (United States)

    Yang, Ying; Wang, Zhi-Hao; Jin, Sen; Gao, Di; Liu, Nan; Chen, Shan-Ping; Zhang, Sinan; Liu, Qing; Liu, Enjie; Wang, Xin; Liang, Xiao; Wei, Pengfei; Li, Xiaoguang; Li, Yin; Yue, Chenyu; Li, Hong-lian; Wang, Ya-Li; Wang, Qun; Ke, Dan; Xie, Qingguo; Xu, Fuqiang; Wang, Liping; Wang, Jian-Zhi

    2016-01-01

    Different emotional states lead to distinct behavioural consequences even when faced with the same challenging events. Emotions affect learning and memory capacities, but the underlying neurobiological mechanisms remain elusive. Here we establish models of learned helplessness (LHL) and learned hopefulness (LHF) by exposing animals to inescapable foot shocks or with anticipated avoidance trainings. The LHF animals show spatial memory potentiation with excitatory monosynaptic upscaling between posterior basolateral amygdale (BLP) and ventral hippocampal CA1 (vCA1), whereas the LHL show memory deficits with an attenuated BLP–vCA1 connection. Optogenetic disruption of BLP–vCA1 inputs abolishes the effects of LHF and impairs synaptic plasticity. By contrast, targeted BLP–vCA1 stimulation rescues the LHL-induced memory deficits and mimics the effects of LHF. BLP–vCA1 stimulation increases synaptic transmission and dendritic plasticity with the upregulation of CREB and intrasynaptic AMPA receptors in CA1. These findings indicate that opposite excitatory monosynaptic scaling of BLP–vCA1 controls LHF- and LHL-modulated spatial memory, revealing circuit-specific mechanisms linking emotions to memory. PMID:27411738

  9. Tracking Active Learning in the Medical School Curriculum: A Learning-Centered Approach

    Science.gov (United States)

    McCoy, Lise; Pettit, Robin K; Kellar, Charlyn; Morgan, Christine

    2018-01-01

    Background: Medical education is moving toward active learning during large group lecture sessions. This study investigated the saturation and breadth of active learning techniques implemented in first year medical school large group sessions. Methods: Data collection involved retrospective curriculum review and semistructured interviews with 20 faculty. The authors piloted a taxonomy of active learning techniques and mapped learning techniques to attributes of learning-centered instruction. Results: Faculty implemented 25 different active learning techniques over the course of 9 first year courses. Of 646 hours of large group instruction, 476 (74%) involved at least 1 active learning component. Conclusions: The frequency and variety of active learning components integrated throughout the year 1 curriculum reflect faculty familiarity with active learning methods and their support of an active learning culture. This project has sparked reflection on teaching practices and facilitated an evolution from teacher-centered to learning-centered instruction. PMID:29707649

  10. The effect of discovery learning and problem-based learning on middle school students’ self-regulated learning

    Science.gov (United States)

    Miatun, A.; Muntazhimah

    2018-01-01

    The aim of this research was to determine the effect of learning models on mathematics achievement viewed from student’s self-regulated learning. The learning model compared were discovery learning and problem-based learning. The population was all students at the grade VIII of Junior High School in Boyolali regency. The samples were students of SMPN 4 Boyolali, SMPN 6 Boyolali, and SMPN 4 Mojosongo. The instruments used were mathematics achievement tests and self-regulated learning questionnaire. The data were analyzed using unbalanced two-ways Anova. The conclusion was as follows: (1) discovery learning gives better achievement than problem-based learning. (2) Achievement of students who have high self-regulated learning was better than students who have medium and low self-regulated learning. (3) For discovery learning, achievement of students who have high self-regulated learning was better than students who have medium and low self-regulated learning. For problem-based learning, students who have high and medium self-regulated learning have the same achievement. (4) For students who have high self-regulated learning, discovery learning gives better achievement than problem-based learning. Students who have medium and low self-regulated learning, both learning models give the same achievement.

  11. Long-lasting spatial learning and memory impairments caused by chronic cerebral hypoperfusion associate with a dynamic change of HCN1/HCN2 expression in hippocampal CA1 region.

    Science.gov (United States)

    Luo, Pan; Lu, Yun; Li, Changjun; Zhou, Mei; Chen, Cheng; Lu, Qing; Xu, Xulin; He, Zhi; Guo, Lianjun

    2015-09-01

    Chronic cerebral hypoperfusion (CCH) causes learning and memory impairments and increases the risk of Alzheimer disease (AD) and vascular dementia (VD) through several biologically plausible pathways, yet the mechanisms underlying the disease process remained unclear particularly in a temporal manner. We performed permanent bilateral occlusion of the common carotid arteries (two-vessel occlusion, 2VO) to induce CCH. To determine whether hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are altered at different stages of cognitive impairment caused by CCH, adult male SD rats were randomly distributed into sham-operated 4, 8 and 12weeks group, 2VO 4, 8 and 12weeks group. Learning and memory performance were evaluated with Morris water maze (MWM) and long-term potentiation (LTP) was used to address the underlying synaptic mechanisms. Expression of NeuN, HCN1 and HCN2 in hippocampal CA1, DG and CA3 areas was quantified by immunohistochemistry and western blotting. Our data showed that CCH induced a remarkable spatial learning and memory deficits in rats of 2VO 4, 8, and 12weeks group although neuronal loss only occurred after 4weeks of 2VO surgery in CA1. In addition, a significant reduction of HCN1 surface expression in CA1 was observed in the group that suffered 4weeks ischemia but neither 8 nor 12weeks. However, HCN2 surface expression in CA1 increased throughout the ischemia time-scales (4, 8 and 12w). Our findings indicate spatial learning and memory deficits in the CCH model are associated with disturbed HCN1 and HCN2 surface expression in hippocampal CA1. The altered patterns of both HCN1 and HCN2 surface expression may be implicated in the early stage (4w) of spatial learning and memory impairments; and the stable and long-lasting impairments of spatial learning and memory may partially attribute to the up-regulated HCN2 surface expression. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Project management support tool implementation. DynaLearn, EC FP7 STREP project 231526, Deliverable D1.1

    NARCIS (Netherlands)

    Bredeweg, B.; Liem, J.

    2009-01-01

    Different project management tools have been evaluated. We have chosen several well-known, flexible and mature tools to support management activities and communication between the DynaLearn project participants. We have created a DynaLearn website for stakeholders outside the DynaLearn website. An

  13. Machine-Learning Research

    OpenAIRE

    Dietterich, Thomas G.

    1997-01-01

    Machine-learning research has been making great progress in many directions. This article summarizes four of these directions and discusses some current open problems. The four directions are (1) the improvement of classification accuracy by learning ensembles of classifiers, (2) methods for scaling up supervised learning algorithms, (3) reinforcement learning, and (4) the learning of complex stochastic models.

  14. New Perspectives on the Search for a Parity Violation Effect in Chiral Molecules

    Science.gov (United States)

    Auguste, F.; Tokunaga, S. K.; Shelkovnikov, A.; Daussy, C.; Amy-Klein, A.; Chardonnet, C.; Darquie, B.

    2013-06-01

    Parity violation (PV) effects have so far never been observed in chiral molecules. Originating from the weak interaction, PV should lead to frequency differences in the rovibrational spectra of the two enantiomers of a chiral molecule. However the smallness of the effect represents a very difficult experimental challenge. We propose to compare the rovibrational spectra (around 10 μm) of two enantiomers, recorded using the ultra-high resolution spectroscopy technique of Doppler-free two-photon Ramsey interferometry in a supersonic molecular beam. With an alternate beam of left- and right-handed molecules and thanks to our expertise in the control of the absolute frequency of the probe CO_2 lasers, we should reach a fractional sensitivity better around 10^{-15} (a few tens of millihertz), on the frequency difference between enantiomers. We will review our latest results on the high-resolution spectroscopy, either in cell or in a supersonic beam, of methyltrioxorhenium. B. Darquié, C. Stoeffler, A. Shelkovnikov, C. Daussy, A. Amy-Klein, C. Chardonnet, S. Zrig, L. Guy, J. Crassous, P. Soulard, P. Asselin, T. R. Huet, P. Schwerdtfeger, R. Bast and T. Saue, Chirality 22, 870 (2010). C. Stoeffler, B. Darquié, A. Shelkovnikov, C. Daussy, A. Amy-Klein, C. Chardonnet, L. Guy, J. Crassous, T. R. Huet, P. Soulard and P. Asselin, Phys. Chem. Chem. Phys. 13, 854 (2011). N. Saleh, S. Zrig, L. Guy, R. Bast, T. Saue, B. Darquié and J. Crassous, submitted to Phys. Chem. Chem. Phys. (2013).

  15. Modeling learning and memory using verbal learning tests: results from ACTIVE.

    Science.gov (United States)

    Gross, Alden L; Rebok, George W; Brandt, Jason; Tommet, Doug; Marsiske, Michael; Jones, Richard N

    2013-03-01

    To investigate the influence of memory training on initial recall and learning. The Advanced Cognitive Training for Independent and Vital Elderly study of community-dwelling adults older than age 65 (n = 1,401). We decomposed trial-level recall in the Auditory Verbal Learning Test (AVLT) and Hopkins Verbal Learning Test (HVLT) into initial recall and learning across trials using latent growth models. Trial-level increases in words recalled in the AVLT and HVLT at each follow-up visit followed an approximately logarithmic shape. Over the 5-year study period, memory training was associated with slower decline in Trial 1 AVLT recall (Cohen's d = 0.35, p = .03) and steep pre- and posttraining acceleration in learning (d = 1.56, p learning, d = 3.10, p memory-trained group had a higher level of recall than the control group through the end of the 5-year study period despite faster decline in learning. This study contributes to the understanding of the mechanisms by which training benefits memory and expands current knowledge by reporting long-term changes in initial recall and learning, as measured from growth models and by characterization of the impact of memory training on these components. Results reveal that memory training delays the worsening of memory span and boosts learning.

  16. Time-place learning and memory persist in mice lacking functional Per1 and Per2 clock genes.

    Science.gov (United States)

    Mulder, C; Van Der Zee, E A; Hut, R A; Gerkema, M P

    2013-12-01

    With time-place learning, animals link a stimulus with the location and the time of day. This ability may optimize resource localization and predator avoidance in daily changing environments. Time-place learning is a suitable task to study the interaction of the circadian system and memory. Previously, we showed that time-place learning in mice depends on the circadian system and Cry1 and/or Cry2 clock genes. We questioned whether time-place learning is Cry specific or also depends on other core molecular clock genes. Here, we show that Per1/Per2 double mutant mice, despite their arrhythmic phenotype, acquire time-place learning similar to wild-type mice. As well as an established role in circadian rhythms, Per genes have also been implicated in the formation and storage of memory. We found no deficiencies in short-term spatial working memory in Per mutant mice compared to wild-type mice. Moreover, both Per mutant and wild-type mice showed similar long-term memory for contextual features of a paradigm (a mild foot shock), measured in trained mice after a 2-month nontesting interval. In contrast, time-place associations were lost in both wild-type and mutant mice after these 2 months, suggesting a lack of maintained long-term memory storage for this type of information. Taken together, Cry-dependent time-place learning does not require Per genes, and Per mutant mice showed no PER-specific short-term or long-term memory deficiencies. These results limit the functional role of Per clock genes in the circadian regulation of time-place learning and memory.

  17. RELATIONSHIP AMONG BRAIN HEMISPHERIC DOMINANCE, ATTITUDE TOWARDS L1 AND L2, GENDER, AND LEARNING SUPRASEGMENTAL FEATURES

    Directory of Open Access Journals (Sweden)

    Mohammad Hadi Mahmoodi

    2016-07-01

    Full Text Available Oral skills are important components of language competence. To have good and acceptable listening and speaking, one must have good pronunciation, which encompasses segmental and suprasegmental features. Despite extensive studies on the role of segmental features and related issues in listening and speaking, there is paucity of research on the role of suprasegmental features in the same domain. Conducting studies which aim at shedding light on the issues related to learning suprasegmental features can help language teachers and learners in the process of teaching/learning English as a foreign language. To this end, this study was designed to investigate the relationship among brain hemispheric dominance, gender, attitudes towards L1 and L2, and learning suprasegmental features in Iranian EFL learners. First, 200 Intermediate EFL learners were selected from different English language teaching institutes in Hamedan and Isfahan, two provinces in Iran, as the sample. Prior to the main stage of the study, Oxford Placement Test (OPT was used to homogenize the proficiency level of all the participants. Then, the participants were asked to complete the Edinburgh Handedness Questionnaire to determine their dominant hemisphere. They were also required to answer two questionnaires regarding their attitudes towards L1 and L2. Finally, the participants took suprasegmental features test. The results of the independent samples t-tests indicated left-brained language learners’ superiority in observing and learning suprasegmental features. It was also found that females are better than males in producing suprasegmental features. Furthermore, the results of Pearson Product Moment Correlations indicated that there is significant relationship between attitude towards L2 and learning suprasegmental features. However, no significant relationship was found between attitude towards L1 and learning English suprasegmental features. The findings of this study can

  18. Lessons Learned from the Node 1 Atmosphere Control and Storage and Water Recovery and Management Subsystem Design

    Science.gov (United States)

    Williams, David E.

    2011-01-01

    Node 1 flew to the International Space Station (ISS) on Flight 2A during December 1998. To date the National Aeronautics and Space Administration (NASA) has learned a lot of lessons from this module based on its history of approximately two years of acceptance testing on the ground and currently its twelve years on-orbit. This paper will provide an overview of the ISS Environmental Control and Life Support (ECLS) design of the Node 1 Atmosphere Control and Storage (ACS) and Water Recovery and Management (WRM) subsystems and it will document some of the lessons that have been learned to date for these subsystems based on problems prelaunch, problems encountered on-orbit, and operational problems/concerns. It is hoped that documenting these lessons learned from ISS will help in preventing them in future Programs.

  19. Conditions for Productive Learning in Network Learning Environments

    DEFF Research Database (Denmark)

    Ponti, M.; Dirckinck-Holmfeld, Lone; Lindström, B.

    2004-01-01

    are designed without a deep understanding of the pedagogical, communicative and collaborative conditions embedded in networked learning. Despite the existence of good theoretical views pointing to a social understanding of learning, rather than a traditional individualistic and information processing approach......The Kaleidoscope1 Jointly Executed Integrating Research Project (JEIRP) on Conditions for Productive Networked Learning Environments is developing and elaborating conceptual understandings of Computer Supported Collaborative Learning (CSCL) emphasizing the use of cross-cultural comparative......: Pedagogical design and the dialectics of the digital artefacts, the concept of collaboration, ethics/trust, identity and the role of scaffolding of networked learning environments.   The JEIRP is motivated by the fact that many networked learning environments in various European educational settings...

  20. Zebrafish as a Model to Study NF1-Associated Learning Deficits

    Science.gov (United States)

    2016-07-01

    and Spencer, 1966). The duration of habituated behavior provides a metric for nonassociative learning ( short - term habituation) and memory formation...ing memory . We evaluated learning by exposing larvae to dark- flash stimuli delivered at 3 s interstimulus intervals (ISIs) and measuring short - term ...behavioral outcomes. The fact that we observed robust improve- ments in learning and memory in our experiments even though we used only short - term

  1. Contribution of Content Knowledge and Learning Ability to the Learning of Facts.

    Science.gov (United States)

    Kuhara-Kojima, Keiko; Hatano, Giyoo

    1991-01-01

    In 3 experiments, 1,598 Japanese college students were examined concerning the learning of facts in 2 content domains, baseball and music. Content knowledge facilitated fact learning only in the relevant domain; learning ability facilitated fact learning in both domains. Effects of content knowledge and learning ability were additive. (SLD)

  2. Dopaminergic mesocortical projections to M1: role in motor learning and motor cortex plasticity

    Directory of Open Access Journals (Sweden)

    Jonas Aurel Hosp

    2013-10-01

    Full Text Available Although the architecture of a dopaminergic (DA system within the primary motorcortex (M1 was well characterized anatomically, its functional significance remainedobscure for a long time. Recent studies in rats revealed that the integrity ofdopaminergic fibers in M1 is a prerequisite for successful acquisition of motor skills.This essential contribution of DA for motor learning is plausible as it modulates M1circuitry at multiple levels thereby promoting plastic changes that are required forinformation storage: at the network level, DA increases cortical excitability andenhances the stability of motor maps. At the cellular level, DA induces the expressionof learning related genes via the transcription factor c-fos. At the level of synapses,DA is required for the formation of long-term potentiation (LTP, a mechanism thatlikely is a fingerprint of a motor memory trace within M1. Dopaminergic fibersinnervating M1 originate within the midbrain, precisely the ventral tegmental area(VTA and the medial portion of substantia nigra (SN. Thus, they could be part of themeso-cortico-limibic pathway – a network that provides information about saliencyand motivational value of an external stimulus and is commonly referred as

  3. Flotillin-1 is an evolutionary-conserved memory-related protein up-regulated in implicit and explicit learning paradigms.

    Science.gov (United States)

    Monje, Francisco J; Divisch, Isabella; Demit, Marvie; Lubec, Gert; Pollak, Daniela D

    2013-06-01

    Studies of synaptic plasticity using the marine mollusk Aplysia californica as model system have been successfully used to identify proteins involved in learning and memory. The importance of molecular elements regulated by the learning- related neurotransmitter serotonin in Aplysia can then be explored in rodent models and finally tested for their relevance for human physiology and pathology. Herein, 2-DE gel-based electrophoresis has been used to investigate protein level changes after treatment with serotonin in Aplysia abdominal ganglia. Twenty-one proteins have been found to be regulated by serotonin, and protein level changes of actin depolymerizing factor (ADF), deleted in azoospermia associated protein (DAZAP-1), and Flotillin-1 have been verified by Western blotting. Flotillin-1, a member of the flotillin/reggie family of scaffolding proteins, has been previously found to be involved in neuritic branching and synapse formation in hippocampal neurons in vitro. However, its importance for hippocampal- dependent learning and memory in the mouse has not been examined. Here, elevated levels of Flotillin-1 in hippocampal tissue of mice trained in the Morris water maze confirmed the relevance of Flotillin-1 for memory-related processes in a mammalian system. Thus, a translational approach-from invertebrates to rodents-led to the identification of Flotillin-1 as evolutionary-conserved memory-related protein.

  4. Educational Modelling Language 1.1 (EML 1.1)

    NARCIS (Netherlands)

    Koper, Rob; Vogten, Hubert; Martens, Harrie

    2003-01-01

    Package contains the EML 1.1 dtd, schema and documentation as is created for the Edubox Player. It is slightly different from IMS Learning Design and provides an intermediate solution between EML 1.0 and IMD Learning Design. The Edubox Player 3.x works on EML 1.1. This package is stored for

  5. Brain Research: Implications for Learning.

    Science.gov (United States)

    Soares, Louise M.; Soares, Anthony T.

    Brain research has illuminated several areas of the learning process: (1) learning as association; (2) learning as reinforcement; (3) learning as perception; (4) learning as imitation; (5) learning as organization; (6) learning as individual style; and (7) learning as brain activity. The classic conditioning model developed by Pavlov advanced…

  6. English language learners' reading self-efficacy and achievement using 1:1 mobile learning devices

    OpenAIRE

    Walters, Jennifer L.

    2012-01-01

    Handheld technology devices allow users to be mobile and access the Internet, personal data, and third-party content applications in many different environments at the users' convenience. The explosion of these mobile learning devices around the globe has led adults to value them for communication, productivity, and learning. Outside of the school setting, many adolescents and children have access to, or own mobile devices. The use of these individual devices by children on a daily basis in s...

  7. Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model

    OpenAIRE

    Lim, Chae-Seok; Hoang, Elizabeth T.; Viar, Kenneth E.; Stornetta, Ruth L.; Scott, Michael M.; Zhu, J. Julius

    2014-01-01

    Fragile X syndrome, caused by the loss of Fmr1 gene function, is the most common form of inherited mental retardation. Lim et al. find that compounds activating serotonin (5HT) subtype 2B receptors or dopamine (DA) subtype 1-like receptors and those inhibiting 5HT2A-Rs or D2-Rs enhance Ras signaling, GluA1-dependent synaptic plasticity, and learning in Fmr1 knockout mice. Combining 5HT and DA compounds at low doses synergistically restored normal learning. This suggests that properly dosed an...

  8. Informal learning.

    Science.gov (United States)

    Callanan, Maureen; Cervantes, Christi; Loomis, Molly

    2011-11-01

    We consider research and theory relevant to the notion of informal learning. Beginning with historical and definitional issues, we argue that learning happens not just in schools or in school-aged children. Many theorists have contrasted informal learning with formal learning. Moving beyond this dichotomy, and away from a focus on where learning occurs, we discuss five dimensions of informal learning that are drawn from the literature: (1) non-didactive, (2) highly socially collaborative, (3) embedded in meaningful activity, (4) initiated by learner's interest or choice, and (5) removed from external assessment. We consider these dimensions in the context of four sample domains: learning a first language, learning about the mind and emotions within families and communities, learning about science in family conversations and museum settings, and workplace learning. Finally, we conclude by considering convergences and divergences across the different literatures and suggesting areas for future research. WIREs Cogni Sci 2011 2 646-655 DOI: 10.1002/wcs.143 For further resources related to this article, please visit the WIREs website. Copyright © 2011 John Wiley & Sons, Ltd.

  9. Model-Free Machine Learning in Biomedicine: Feasibility Study in Type 1 Diabetes

    Science.gov (United States)

    Daskalaki, Elena; Diem, Peter; Mougiakakou, Stavroula G.

    2016-01-01

    Although reinforcement learning (RL) is suitable for highly uncertain systems, the applicability of this class of algorithms to medical treatment may be limited by the patient variability which dictates individualised tuning for their usually multiple algorithmic parameters. This study explores the feasibility of RL in the framework of artificial pancreas development for type 1 diabetes (T1D). In this approach, an Actor-Critic (AC) learning algorithm is designed and developed for the optimisation of insulin infusion for personalised glucose regulation. AC optimises the daily basal insulin rate and insulin:carbohydrate ratio for each patient, on the basis of his/her measured glucose profile. Automatic, personalised tuning of AC is based on the estimation of information transfer (IT) from insulin to glucose signals. Insulin-to-glucose IT is linked to patient-specific characteristics related to total daily insulin needs and insulin sensitivity (SI). The AC algorithm is evaluated using an FDA-accepted T1D simulator on a large patient database under a complex meal protocol, meal uncertainty and diurnal SI variation. The results showed that 95.66% of time was spent in normoglycaemia in the presence of meal uncertainty and 93.02% when meal uncertainty and SI variation were simultaneously considered. The time spent in hypoglycaemia was 0.27% in both cases. The novel tuning method reduced the risk of severe hypoglycaemia, especially in patients with low SI. PMID:27441367

  10. Learning Together 1: an educational model for training GPs, paediatricians: initial findings.

    Science.gov (United States)

    Macaulay, Chloe; Spicer, John; Riches, Wendy; Lakhanpaul, Monica

    2017-01-01

    Learning Together is primarily an educational intervention, where paediatric registrars [SpRs] and General Practice (GP) registrars [GPSTs] see children together in a primary care setting. Over a six month period in 2013/2014, 44 learning pairs were set up mainly in North East and Central London. Proof of concept for the model at scale was achieved. Reported learning demonstrated: clinical learning themes of new knowledge, skill and communication skills; and collaborative themes of ongoing collaboration, satisfaction with team working and change in attitudes. These themes were identified in both sets of trainees. The self-reported learning is backed up by the results of a retrospective notes review of four common conditions based on NICE guidelines; constipation, asthma, feverish illness and eczema (CAFE). Guidance adherence improved from 57% before the intervention in solo GP training consultations to 72% during the joint clinic intervention (p Learning Together in its South London extension.

  11. Applying cheerful disco learning for improving of motivation and learning result of PKn in grade viii c students junior high school 1 Kebumen in second semester 2013/2014 academic years

    Directory of Open Access Journals (Sweden)

    Siti Makmuroh

    2017-06-01

    Full Text Available The aim of this classroom action research is to improve students’ learning motivation, learning result of PKn on Basic Competence of Describing Indonesian Government System and the Roles of the State Institutions as the Sovereignty Executive and the characters of Grade VIII C Students of Junior High School 1 of Kebumen in Second Semester of Academic Year 2013/2014 by applying CHEERFUL DISCO learning method. The research is a classroom action research conducted in two cycles; each cycle of which includes planning, conducting, observation, and reflection. The result of the research shows that the learning method was able to improve the students’ learning motivation in learning activities from 62.37% in pre cycle to 73.74% in the first cycle, then from 78.91% in the second cycle, improved the PKn learning achievement in mastering concept of the ability to describe Indonesian Government System and the Roles of the State Institutions as the Sovereignty Executive, which can be seen that the students’ achievement test result is improving in average from 78.18 with 54.55% of mastery learning in pre cycle to 83.23 with 72.73% of mastery learning in the first cycle, then it was improved to 86.59 in average with 81.82% of mastery learning in the second cycle.

  12. Adolescent changes in dopamine D1 receptor expression in orbitofrontal cortex and piriform cortex accompany an associative learning deficit.

    Directory of Open Access Journals (Sweden)

    Anna K Garske

    Full Text Available The orbitofrontal cortex (OFC and piriform cortex are involved in encoding the predictive value of olfactory stimuli in rats, and neural responses to olfactory stimuli in these areas change as associations are learned. This experience-dependent plasticity mirrors task-related changes previously observed in mesocortical dopamine neurons, which have been implicated in learning the predictive value of cues. Although forms of associative learning can be found at all ages, cortical dopamine projections do not mature until after postnatal day 35 in the rat. We hypothesized that these changes in dopamine circuitry during the juvenile and adolescent periods would result in age-dependent differences in learning the predictive value of environmental cues. Using an odor-guided associative learning task, we found that adolescent rats learn the association between an odor and a palatable reward significantly more slowly than either juvenile or adult rats. Further, adolescent rats displayed greater distractibility during the task than either juvenile or adult rats. Using real-time quantitative PCR and immunohistochemical methods, we observed that the behavioral deficit in adolescence coincides with a significant increase in D1 dopamine receptor expression compared to juvenile rats in both the OFC and piriform cortex. Further, we found that both the slower learning and increased distractibility exhibited in adolescence could be alleviated by experience with the association task as a juvenile, or by an acute administration of a low dose of either the dopamine D1 receptor agonist SKF-38393 or the D2 receptor antagonist eticlopride. These results suggest that dopaminergic modulation of cortical function may be important for learning the predictive value of environmental stimuli, and that developmental changes in cortical dopaminergic circuitry may underlie age-related differences in associative learning.

  13. The evolution of e-learning and e-learning in evolution

    Directory of Open Access Journals (Sweden)

    Anna Lamandini

    2009-07-01

    Full Text Available In this article the author sets out to compare and analyse models for e-learning that have evolved passing from the characteristics of Web 1.0 to those of Web 2.0, and to propose 2 possible applications: PLE or Personal Learning Environment and VLP or Virtual Learning Place. For each one, specific aspects and guidance are highlighted while recognising that the concept of E- learning has evolved in connection with Lifelong Learning in the programmes and actions of the European Commission.

  14. ANÁLISIS DE UN BROTE DE SARAMPIÓN EN UNA BARRIADA DE LA PROVINCIA DE SEVILLA, ESPAÑA

    Directory of Open Access Journals (Sweden)

    Antonio Luna Sánchez

    2013-01-01

    Full Text Available Fundamentos: En 2011 en Sevilla (España un brote de Sarampión afec- tó a 1.759 personas. Comenzó en la Barriada de Santa Isabel, San Juan de Az- nalfarache (Sevilla, donde reside una comunidad Romaní. El objetivo del trabajo es describir epidemiologicamente el brote en la localidad y calcular el riesgo de enfermar por sarampión de los residentes en la barriada Santa Isa- bel. Método: Se diseñó un estudio de cohortes retrospectivo. Se consideró población expuesta a los residentes en la barriada de Santa Isabel y no ex- puesta a la del resto del municipio. Las fuentes de datos fueron: el Instituto de Estadística de Andalucía, el Ayuntamiento del municipio y el Sistema de Vi- gilancia Epidemiológica de Andalucía. Se describió el brote y se calcularon incidencias y el Riesgo Relativo. Los casos fueron confirmados por criterios clínicos, de laboratorio y/o epidemiológicos. Resultados: En la barriada los casos se concentraron entre el colectivo etario de entre 2 y 19 años, mientras que en el resto de la localidad se produ- jo en menores de 2 y mayores de 19 años. La incidencia global del brote fue de 0,98 por 1.000 habitantes. En San Juan de 4,94 . Entre los expuestos fue de 23,15 y de 2,1 en los no expuestos. En el colectivo de 2 a 19 años la inciden- cia fue 89,58 por 1.000 habitantes en la Barriada y de 5,33 por 1.000 habitan- tes en el resto de la localidad. Conclusiones: El brote afectó en mayor medida a menores de 20 años, a población no vacunada y residente en la Barriada Santa Isabel. El riesgo de enfermar de Sarampión en la Barriada fue de 11 y de 17 en el colectivo entre 2 y 19 años. Precisamos elaborar estrategias que reduzcan las desigualdades en salud que acompañan a algunos brotes epidémicos.

  15. Mathematics Achievement with Digital Game-Based Learning in High School Algebra 1 Classes

    Science.gov (United States)

    Ferguson, Terri Lynn Kurley

    2014-01-01

    This study examined the impact of digital game-based learning (DGBL) on mathematics achievement in a rural high school setting in North Carolina. A causal comparative research design was used in this study to collect data to determine the effectiveness of DGBL in high school Algebra 1 classes. Data were collected from the North Carolina…

  16. 1:1 (dis)section - Learning through full-scale dissection and transformations of abandoned buildings

    DEFF Research Database (Denmark)

    Krag, Mo Michelsen Stochholm; Keiding, Tina Bering

    2018-01-01

    This paper reports on four transformation workshops. The aim was to provide first-year students with an understanding of the relation between the section as a semantic representation and the materiality, structure and spatial relations of a concrete building. The culmination of each workshop...... was a full-scale dissection and transformation of an abandoned house. As we shall see, the workshops fulfilled not only the intended learning goals, but created an unforeseen and unique context for learning about the relations between building, place and place....

  17. EFFECTS OF INQUIRY TRAINING LEARNING MODEL BASED MULTIMEDIA AND MOTIVATION OF PHYSICS STUDENT LEARNING OUTCOMES

    Directory of Open Access Journals (Sweden)

    Hayati .

    2013-06-01

    Full Text Available The objective in this research: (1 Determine a better learning model to improve learning outcomes physics students among learning model Inquiry Training based multimedia and Inquiry Training learning model. (2 Determine the level of motivation to learn in affects physics student learning outcomes. (3 Knowing the interactions between the model of learning and motivation in influencing student learning outcomes. This research is a quasi experimental. The population in this research was all students in class XI SMA Negeri 1 T.P Sunggal Semester I 2012/2013. The sample of this research was consisted of two classes with a sample of 70 peoples who are determined by purposive sampling, the IPA XI-2 as a class experiment using a model-based multimedia learning Training Inquiry as many as 35 peoples and XI IPA-3 as a control class using learning model Inquiry Training 35 peoples. Hypotheses were analyzed using the GLM at significant level of 0.05 using SPSS 17.0 for Windows. Based on data analysis and hypothesis testing conducted found that: (1 Training Inquiry-based multimedia learning model in improving student learning outcomes rather than learning model physics Inquiry Training. (2 The results of studying physics students who have high motivation to learn better than students who have a low learning motivation. (3 From this research there was an interaction between learning model inquiry-based multimedia training and motivation to study on learning outcomes of students.

  18. Supervised Learning for Dynamical System Learning.

    Science.gov (United States)

    Hefny, Ahmed; Downey, Carlton; Gordon, Geoffrey J

    2015-01-01

    Recently there has been substantial interest in spectral methods for learning dynamical systems. These methods are popular since they often offer a good tradeoff between computational and statistical efficiency. Unfortunately, they can be difficult to use and extend in practice: e.g., they can make it difficult to incorporate prior information such as sparsity or structure. To address this problem, we present a new view of dynamical system learning: we show how to learn dynamical systems by solving a sequence of ordinary supervised learning problems, thereby allowing users to incorporate prior knowledge via standard techniques such as L 1 regularization. Many existing spectral methods are special cases of this new framework, using linear regression as the supervised learner. We demonstrate the effectiveness of our framework by showing examples where nonlinear regression or lasso let us learn better state representations than plain linear regression does; the correctness of these instances follows directly from our general analysis.

  19. A 1-night operant learning task without food-restriction differentiates among mouse strains in an automated home-cage environment.

    Science.gov (United States)

    Remmelink, Esther; Loos, Maarten; Koopmans, Bastijn; Aarts, Emmeke; van der Sluis, Sophie; Smit, August B; Verhage, Matthijs

    2015-04-15

    Individuals are able to change their behavior based on its consequences, a process involving instrumental learning. Studying instrumental learning in mice can provide new insights in this elementary aspect of cognition. Conventional appetitive operant learning tasks that facilitate the study of this form of learning in mice, as well as more complex operant paradigms, require labor-intensive handling and food deprivation to motivate the animals. Here, we describe a 1-night operant learning protocol that exploits the advantages of automated home-cage testing and circumvents the interfering effects of food restriction. The task builds on behavior that is part of the spontaneous exploratory repertoire during the days before the task. We compared the behavior of C57BL/6J, BALB/cJ and DBA/2J mice and found various differences in behavior during this task, but no differences in learning curves. BALB/cJ mice showed the largest instrumental learning response, providing a superior dynamic range and statistical power to study instrumental learning by using this protocol. Insights gained with this home-cage-based learning protocol without food restriction will be valuable for the development of other, more complex, cognitive tasks in automated home-cages. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Experimental Study of Learning French in the Public Schools: Report #1, 1959-60.

    Science.gov (United States)

    Toronto Board of Education (Ontario). Research Dept.

    An experiment in language instruction undertaken in Canadian junior high schools during the 1960-61 school year is reported in this study. The pilot project: (1) examines the phenomena of learning to comprehend and speak French through two different but direct modes of instruction; (2) compares by achievement tests the results of the two modes of…

  1. Dual mechanisms governing reward-driven perceptual learning [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Dongho Kim

    2015-09-01

    Full Text Available In this review, we explore how reward signals shape perceptual learning in animals and humans. Perceptual learning is the well-established phenomenon by which extensive practice elicits selective improvement in one’s perceptual discrimination of basic visual features, such as oriented lines or moving stimuli. While perceptual learning has long been thought to rely on ‘top-down’ processes, such as attention and decision-making, a wave of recent findings suggests that these higher-level processes are, in fact, not necessary.  Rather, these recent findings indicate that reward signals alone, in the absence of the contribution of higher-level cognitive processes, are sufficient to drive the benefits of perceptual learning. Here, we will review the literature tying reward signals to perceptual learning. Based on these findings, we propose dual underlying mechanisms that give rise to perceptual learning: one mechanism that operates ‘automatically’ and is tied directly to reward signals, and another mechanism that involves more ‘top-down’, goal-directed computations.

  2. Development of inquiry-based learning activities integrated with the local learning resource to promote learning achievement and analytical thinking ability of Mathayomsuksa 3 student

    Science.gov (United States)

    Sukji, Paweena; Wichaidit, Pacharee Rompayom; Wichaidit, Sittichai

    2018-01-01

    The objectives of this study were to: 1) compare learning achievement and analytical thinking ability of Mathayomsuksa 3 students before and after learning through inquiry-based learning activities integrated with the local learning resource, and 2) compare average post-test score of learning achievement and analytical thinking ability to its cutting score. The target of this study was 23 Mathayomsuksa 3 students who were studying in the second semester of 2016 academic year from Banchatfang School, Chainat Province. Research instruments composed of: 1) 6 lesson plans of Environment and Natural Resources, 2) the learning achievement test, and 3) analytical thinking ability test. The results showed that 1) student' learning achievement and analytical thinking ability after learning were higher than that of before at the level of .05 statistical significance, and 2) average posttest score of student' learning achievement and analytical thinking ability were higher than its cutting score at the level of .05 statistical significance. The implication of this research is for science teachers and curriculum developers to design inquiry activities that relate to student's context.

  3. Developing a Personal-Learning-Portfolio (PLP) for 1st year students at Department of Psychology

    DEFF Research Database (Denmark)

    Johnsen, Anna Thit; Beck Hansen, Nina; Andersen, Mette Elmose

    Abstract title: Developing a Personal-Learning-Portfolio (PLP) for 1st year students at Department of Psychology Learning outcome of activity: B01 is the first module of the education in Psychology at University of Southern Denmark (SDU). The aim of B01 is to give the students a ‘map...... different strategies: first the overall framework of the PLP is discussed and second we conduct cognitive interviews evaluating the comprehensibility and relevance of the questions posed in the PLP. The PLP is then adapted based on the comments from the students. The development and initial testing...... be an inspiration to others who wish to develop and implements PLPs. Second, we will show the format of our particular Personal-Learning-Portfolio together with reflections on why it was developed in such a way. This includes the students’ opinions about the PLP and the results of the cognitive interviews....

  4. TENCompetence Learning Design Toolkit, Runtime component, ccsi_v3_2_10c_v1_4

    NARCIS (Netherlands)

    Sharples, Paul; Popat, Kris; Llobet, Lau; Santos, Patricia; Hernández-Leo, Davinia; Miao, Yongwu; Griffiths, David; Beauvoir, Phillip

    2010-01-01

    Sharples, P., Popat, K., Llobet, L., Santos, P., Hernandez-Leo, D., Miao, Y., Griffiths, D. & Beauvoir, P. (2009) TENCompetence Learning Design Toolkit, Runtime component, ccsi_v3_2_10c_v1_4 This release is composed of three files corresponding to CopperCore Service Integration (CCSI) v3.2-10cv1.4,

  5. INFLUENCE OF PARENTS' SOCIO-ECONOMIC STATUS AND VOCATIONAL LEARNING MOTIVATION TO LEARNING ACHIEVEMENT IN THE LESSON OF CHASSIS AND POWER TRANSDUCTOR FOR XII GRADE STUDENTS OF LIGHT VIHICLE ENGINEERING DEPARTMENT OF SMK PIRI 1 YOGYAKARTA IN ACADEMIC YEAR 2013/2014

    Directory of Open Access Journals (Sweden)

    Indra Tri Setyawan

    2014-06-01

    Full Text Available The purpose of the study is to find the influence of parents’ socio-economic status and vocational learning motivation to learning achievement in the lesson of chassis and power transductor for XII grade students of SMK PIRI 1 Yogyakarta in the academic year 2013/2014. This research includes ex-post facto research conducted on the population 129 students with the sample 98 students. Data collection techniques in this research uses questionnaire instrument techniques for variable of parents’ socio-economic status and vocational learning motivation whereas documentation instrument techniques uses for variable of learning achievement the lesson of chassis and power transductor. Questionnaire was tested on 25 respondents. Data analysis techniques uses partial correlation analysis and regression analysis were preceded by prerequisite test that are normality test, linearity and multikolonieritas. The results of the data analysis is (1 parents’ socio-economic status (X1 influential positive and significant on learning achievement in the lesson of chassis and power transductor, (2 vocational learning motivation (X2 influential positive and significant on learning achievement in the lesson of chassis and power transductor, (3 parents’ socio-economic status (X1 and vocational learning motivation (X2 are jointly have positive and significant effect on learning achievement in the lesson of chassis and power transductor. Positive means that the higher the value of X1 and X2, the higher the value of Y, and vice versa. Thus, the socio-economic status of parents and the motivation to study vocational subjects affecting learning achievement the lesson of chassis and power transductor XII grade students of SMK PIRI 1 Yogyakarta in the academic year 2013/2014.

  6. The Application Model of Learning Cycle 5e in Subject Matter of Magnitude and Derivative at Class VII Junior High School 1 Sengah Temila

    Directory of Open Access Journals (Sweden)

    Ira Nofita Sari

    2016-10-01

    Penelitian ini bertujuan untuk mengetahui penerapan model learning cycle 5 e pada materi besaran pokok dan turunankelas VII SMP Negeri 1 Sengah Temila. Penelitian ini termasuk penelitian quasi eksperiment dengan rancangan posttest only design control design. Alat pengumpul data yang digunakan adalah tes pilihan jamak. Hipotesis diuji menggunakanuji t satu pihak. Berdasarkan hasil analisis data disimpulkan bahwa: (1 hasil belajar siswa setelah diterapkan model learning cycle 5 e pada materi besaran pokok dan turunan kelas VII SMP Negeri 1 Sengah Temilatergolong baik, (2 hasil belajar siswa setelah diterapkan model learning cycle 5 e pada materi besaran pokok dan turunan kelas VII SMP Negeri 1 Sengah Temilatergolong kurang, dan (3 hasil belajar siswa setelah diterapkan model learning cycle 5 e lebih baik daripada hasil belajar siswa setelah diterapkan model pembelajaran konvensional pada materi besaran pokok dan turunan kelas VII SMP Negeri 1 Sengah Temila. Kata kunci: besaran pokok dan turunan, hasil belajar, model learning cycle 5e

  7. Odor Preference Learning and Memory Modify GluA1 Phosphorylation and GluA1 Distribution in the Neonate Rat Olfactory Bulb: Testing the AMPA Receptor Hypothesis in an Appetitive Learning Model

    Science.gov (United States)

    Cui, Wen; Darby-King, Andrea; Grimes, Matthew T.; Howland, John G.; Wang, Yu Tian; McLean, John H.; Harley, Carolyn W.

    2011-01-01

    An increase in synaptic AMPA receptors is hypothesized to mediate learning and memory. AMPA receptor increases have been reported in aversive learning models, although it is not clear if they are seen with memory maintenance. Here we examine AMPA receptor changes in a cAMP/PKA/CREB-dependent appetitive learning model: odor preference learning in…

  8. Infants' Learning, Memory, and Generalization of Learning for Bimodal Events.

    Science.gov (United States)

    Morrongiello, Barbara A.; Lasenby, Jennifer; Lee, Naomi

    2003-01-01

    Two studies examined the impact of temporal synchrony on infants' learning of and memory for sight-sound pairs. Findings indicated that 7-month-olds had no difficulty learning auditory-visual pairs regardless of temporal synchrony, remembering them 10 minutes later and 1 week later. Three-month-olds showed poorer learning in no-synchrony than in…

  9. Model-Free Machine Learning in Biomedicine: Feasibility Study in Type 1 Diabetes.

    Directory of Open Access Journals (Sweden)

    Elena Daskalaki

    Full Text Available Although reinforcement learning (RL is suitable for highly uncertain systems, the applicability of this class of algorithms to medical treatment may be limited by the patient variability which dictates individualised tuning for their usually multiple algorithmic parameters. This study explores the feasibility of RL in the framework of artificial pancreas development for type 1 diabetes (T1D. In this approach, an Actor-Critic (AC learning algorithm is designed and developed for the optimisation of insulin infusion for personalised glucose regulation. AC optimises the daily basal insulin rate and insulin:carbohydrate ratio for each patient, on the basis of his/her measured glucose profile. Automatic, personalised tuning of AC is based on the estimation of information transfer (IT from insulin to glucose signals. Insulin-to-glucose IT is linked to patient-specific characteristics related to total daily insulin needs and insulin sensitivity (SI. The AC algorithm is evaluated using an FDA-accepted T1D simulator on a large patient database under a complex meal protocol, meal uncertainty and diurnal SI variation. The results showed that 95.66% of time was spent in normoglycaemia in the presence of meal uncertainty and 93.02% when meal uncertainty and SI variation were simultaneously considered. The time spent in hypoglycaemia was 0.27% in both cases. The novel tuning method reduced the risk of severe hypoglycaemia, especially in patients with low SI.

  10. Animasi E-learning Pembelajaran Matematika dan Fisika Bagi Siswa Sekolah Menengah Pertama Kelas 1

    OpenAIRE

    Nurcahyani Dewi Retnowati; Mahmuda Ghazni Rahmawan

    2016-01-01

    Learning through the use of animation E-Learning can be a learning tool to teach using electronic applications, media, Internet, Intranet or other computer network media. In addition to computers and Internet networks, which play a role in e-learning is the brainware that is creating content (text, images, video, animation) and user/users of e-learning (teachers and students). It should be noted in making animated e-learning is the content that should be included in accordance with the curric...

  11. Talons and beaks are viable but underutilized samples for detecting ...

    African Journals Online (AJOL)

    Talons and beaks are viable but underutilized samples for detecting organophosphorus and carbamate pesticide poisoning in raptors. Ngaio Richards, Irene Zorrilla, Joseph Lalah, Peter Otieno, Isabel Fernandez, Monica Calvino, Joaquin Garcia ...

  12. Peron võitleb enda Argentinale väljaandmisega / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2007-01-01

    Argentina endisel presidendil Isabel Peronil oli Argentina praeguse võimu hinnangul kontakte nn. surmaüksustega, mis mõrvasid vasakpoolseid aktiviste. I. Peron pandi Hispaanias koduaresti. Lisa: Ööklubi lavalt presidenditoolile

  13. D4.1 Learning analytics: theoretical background, methodology and expected results

    NARCIS (Netherlands)

    Tammets, Kairit; Laanpere, Mart; Eradze, Maka; Brouns, Francis; Padrón-Nápoles, Carmen; De Rosa, Rosanna; Ferrari, Chiara

    2014-01-01

    The purpose of the EMMA project is to showcase excellence in innovative teaching methodologies and learning approaches through the large-scale piloting of MOOCs on different subjects. The main objectives related with the implementation of learning analytics in EMMa project are to: ● develop the

  14. Facilitated stimulus-response associative learning and long-term memory in mice lacking the NTAN1 amidase of the N-end rule pathway.

    Science.gov (United States)

    Balogh, S A; McDowell, C S; Tae Kwon, Y; Denenberg, V H

    2001-02-23

    The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. Inactivation of the NTAN1 gene encoding the asparagine-specific N-terminal amidase in mice results in impaired spatial memory [26]. The studies described here were designed to further characterize the effects upon learning and memory of inactivating the NTAN1 gene. NTAN1-deficient mice were found to be better than wild-type mice on black-white and horizontal-vertical discrimination learning. They were also better at 8-week Morris maze retention testing when a reversal trial was not included in the testing procedures. In all three tasks NTAN1-deficient mice appeared to use a strong win-stay strategy. It is concluded that inactivating the asparagine-specific branch of the N-end rule pathway in mice results in impaired spatial learning with concomitant compensatory restructuring of the nervous system in favor of non-spatial (stimulus-response) learning.

  15. ANALYSIS LEARNING MODEL OF DISCOVERY AND UNDERSTANDING THE CONCEPT PRELIMINARY TO PHYSICS LEARNING OUTCOMES SMA

    Directory of Open Access Journals (Sweden)

    Sri Rosepda Sebayang

    2015-12-01

    Full Text Available This study aims: 1 to determine whether the student learning outcomes using discovery learning is better than conventional learning 2 To determine whether the learning outcomes of students who have a high initial concept understanding better then of low initial concept understanding, and 3 to determine the effect of interaction discovery learning and understanding of the initial concept of the learning outcomes of students. The samples in this study was taken by cluster random sampling two classes where class X PIA 3 as a class experiment with applying discovery learning and class X PIA 2 as a control class by applying conventional learning. The instrument used in this study is a test of learning outcomes in the form of multiple-choice comprehension test initial concept description form. The results of research are: 1 learning outcomes of students who were taught with discovery learning is better than the learning outcomes of students who are taught by conventional learning, 2 student learning outcomes with high initial conceptual understanding better than the learning outcomes of students with low initial conceptual understanding, and 3 there was no interaction between discovery learning and understanding of initial concepts for the student learning outcomes.

  16. MULTIMEDIA LEARNING IMPLEMENTATION AND VOCABULARY MASTERY FOR ENHANCHING STUDENTS’ JAPANESE LANGUAGE READING SKILL AT SMKN 1 PURWOKERTO

    Directory of Open Access Journals (Sweden)

    Haryono Haryono

    2015-06-01

    Full Text Available The present research is the implementation of the 2013 doctoral disertation report funded by DIKTI. The research is a part of IPTEKS scheme for community devotion that have strong relation to language education technology. It concern with the use of multimedia learning and vocabulary mastery on students’ Japanese language  reading skills at SMK 1 Purwokerto. The method is implemented experimentally by giving multimedia learning treatment such as Rosetta Stone and Tell Me More Japanese. Through some presentation with the use of those multimedia learning material, the purpose of this research is to know the extent to which the level of their vocabulary mastery and to encourage students in order to have an approriate skill to read Japanese documents. With the implementation of this multimedia learning training, graduate students of SMK Negeri I Purwokerto will be increased and for the future they have a good job at Japanese companies in Indonesia

  17. Developing mathematics learning set for special-needs junior high school student oriented to learning interest and achievement

    Directory of Open Access Journals (Sweden)

    Ai Sadidah

    2016-11-01

    Full Text Available This study aims to produce a mathematics learning set for special-needs students (mathematical learning disability and mathematically gifted of Junior High School Grade VIII Second Semester oriented to learning interests and achievement which is valid, practical, and effective. This study was a research and development study using the Four-D development model consisting of four stages: (1 define, (2 design, (3 develop, and (4 disseminate. The quality of learning set consisting of the following three criterions: (1 validity, (2 practicality, and (3 effectiveness.  The data analysis technique used in this study is a descriptive quantitative analysis. The research produced learning set consisting of lesson plans and student worksheets. The result of the research shows that: (1 the learning set fulfill the valid criteria base on experts’ appraisal; (2 the learning set fulfill the practical criterion base on teacher’s and students’ questionnaire, and observation of learning implementation; (3 the learning set fulfill the effectiveness criterion base on learning interest and achievement.

  18. The E-learning Cabaret: do's and don'ts in E-Learning Design

    NARCIS (Netherlands)

    Westera, Wim

    2009-01-01

    Westera, W. (2006). The E-Learning Cabaret: do's and don'ts in E-Learning Design. Book of Abstracts, 12th International Conference on Technology Supported Learning & Teaching, Online Educa Berlin (pp. 169-171). November, 29-December, 1, 2006, Berlin, Germany: ICWE-GmbH.

  19. Does Cry1Ab protein affect learning performances of the honey bee Apis mellifera L. (Hymenoptera, Apidae)?

    Science.gov (United States)

    Ramirez-Romero, R; Desneux, N; Decourtye, A; Chaffiol, A; Pham-Delègue, M H

    2008-06-01

    Genetically modified Bt crops are increasingly used worldwide but side effects and especially sublethal effects on beneficial insects remain poorly studied. Honey bees are beneficial insects for natural and cultivated ecosystems through pollination. The goal of the present study was to assess potential effects of two concentrations of Cry1Ab protein (3 and 5000 ppb) on young adult honey bees. Following a complementary bioassay, our experiments evaluated effects of the Cry1Ab on three major life traits of young adult honey bees: (a) survival of honey bees during sub-chronic exposure to Cry1Ab, (b) feeding behaviour, and (c) learning performance at the time that honey bees become foragers. The latter effect was tested using the proboscis extension reflex (PER) procedure. The same effects were also tested using a chemical pesticide, imidacloprid, as positive reference. The tested concentrations of Cry1Ab protein did not cause lethal effects on honey bees. However, honey bee feeding behaviour was affected when exposed to the highest concentration of Cry1Ab protein, with honey bees taking longer to imbibe the contaminated syrup. Moreover, honey bees exposed to 5000 ppb of Cry1Ab had disturbed learning performances. Honey bees continued to respond to a conditioned odour even in the absence of a food reward. Our results show that transgenic crops expressing Cry1Ab protein at 5000 ppb may affect food consumption or learning processes and thereby may impact honey bee foraging efficiency. The implications of these results are discussed in terms of risks of transgenic Bt crops for honey bees.

  20. Comparing concentration methods: parasitrap® versus Kato-Katz for ...

    African Journals Online (AJOL)

    Comparing concentration methods: parasitrap® versus Kato-Katz for studying the prevalence of Helminths in Bengo province, Angola. Clara Mirante, Isabel Clemente, Graciette Zambu, Catarina Alexandre, Teresa Ganga, Carlos Mayer, Miguel Brito ...

  1. The role of 5-HT(1A) receptors in learning and memory.

    Science.gov (United States)

    Ogren, Sven Ove; Eriksson, Therese M; Elvander-Tottie, Elin; D'Addario, Claudio; Ekström, Joanna C; Svenningsson, Per; Meister, Björn; Kehr, Jan; Stiedl, Oliver

    2008-12-16

    The ascending serotonin (5-HT) neurons innervate the cerebral cortex, hippocampus, septum and amygdala, all representing brain regions associated with various domains of cognition. The 5-HT innervation is diffuse and extensively arborized with few synaptic contacts, which indicates that 5-HT can affect a large number of neurons in a paracrine mode. Serotonin signaling is mediated by 14 receptor subtypes with different functional and transductional properties. The 5-HT(1A) subtype is of particular interest, since it is one of the main mediators of the action of 5-HT. Moreover, the 5-HT(1A) receptor regulates the activity of 5-HT neurons via autoreceptors, and it regulates the function of several neurotransmitter systems via postsynaptic receptors (heteroreceptors). This review assesses the pharmacological and genetic evidence that implicates the 5-HT(1A) receptor in learning and memory. The 5-HT(1A) receptors are in the position to influence the activity of glutamatergic, cholinergic and possibly GABAergic neurons in the cerebral cortex, hippocampus and in the septohippocampal projection, thereby affecting declarative and non-declarative memory functions. Moreover, the 5-HT(1A) receptor regulates several transduction mechanisms such as kinases and immediate early genes implicated in memory formation. Based on studies in rodents the stimulation of 5-HT(1A) receptors generally produces learning impairments by interfering with memory-encoding mechanisms. In contrast, antagonists of 5-HT(1A) receptors facilitate certain types of memory by enhancing hippocampal/cortical cholinergic and/or glutamatergic neurotransmission. Some data also support a potential role for the 5-HT(1A) receptor in memory consolidation. Available results also implicate the 5-HT(1A) receptor in the retrieval of aversive or emotional memories, supporting an involvement in reconsolidation. The contribution of 5-HT(1A) receptors in cognitive impairments in various psychiatric disorders is still

  2. BRINE SHRIMP LETHALITY BIOASSAY OF GLAUCIUM GRANDIFLORUM VAR. GRANDIFLORUM

    OpenAIRE

    A. SARI, Ç. ÜNSAL, İ. SARIOĞLU, A. SARI, Ç. ÜNSAL, İ. SARIOĞLU

    2013-01-01

    Türkiye'nin 3 farklı bölgesinden toplanan Glaucium grandiflorum Boiss. et Huet var. grandiflorum örneklerinin toprak üstü kısımlarından elde edilen alkaloit ekstreleri ve bu ekstrelerden elde edilen majör alkaloitler allokriptopin, protopİn, (+)-izokoridin, (+)-korİdin üzerinde brİne shrimp lethality testi yapılarak sitotoksisiteleri İncelenmiştir. Glaucium grandiflorum var. grandiflorum türünün 3 örneği de önemli oranda sitotoksik aktİvite göstermiştir. Allokriptopin, protopin, (+)-izok...

  3. Towards a nonequilibrium quantum field theory approach to electroweak baryogenesis

    International Nuclear Information System (INIS)

    Riotto, A.

    1996-01-01

    We propose a general method to compute CP violating observables from extensions of the standard model in the context of electroweak baryogenesis. It is an alternative to the one recently developed by Huet and Nelson and relies on a nonequilibrium quantum field theory approach. The method is valid for all shapes and sizes of the bubble wall expanding in the thermal bath during a first-order electroweak phase transition. The quantum physics of CP violation and its suppression coming from the incoherent nature of thermal processes are also made explicit. copyright 1996 The American Physical Society

  4. Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.

    Directory of Open Access Journals (Sweden)

    Federico Fuentes

    Full Text Available ER-bound PTP1B is expressed in hippocampal neurons, and accumulates among neurite contacts. PTP1B dephosphorylates ß-catenin in N-cadherin complexes ensuring cell-cell adhesion. Here we show that endogenous PTP1B, as well as expressed GFP-PTP1B, are present in dendritic spines of hippocampal neurons in culture. GFP-PTP1B overexpression does not affect filopodial density or length. In contrast, impairment of PTP1B function or genetic PTP1B-deficiency leads to increased filopodia-like dendritic spines and a reduction in mushroom-like spines, while spine density is unaffected. These morphological alterations are accompanied by a disorganization of pre- and post-synapses, as judged by decreased clustering of synapsin-1 and PSD-95, and suggest a dynamic synaptic phenotype. Notably, levels of ß-catenin-Tyr-654 phosphorylation increased ∼5-fold in the hippocampus of adult PTP1B(-/- (KO mice compared to wild type (WT mice and this was accompanied by a reduction in the amount of ß-catenin associated with N-cadherin. To determine whether PTP1B-deficiency alters learning and memory, we generated mice lacking PTP1B in the hippocampus and cortex (PTP1B(fl/fl-Emx1-Cre. PTP1B(fl/fl-Emx1-Cre mice displayed improved performance in the Barnes maze (decreased time to find and enter target hole, utilized a more efficient strategy (cued, and had better recall compared to WT controls. Our results implicate PTP1B in structural plasticity within the hippocampus, likely through modulation of N-cadherin function by ensuring dephosphorylation of ß-catenin on Tyr-654. Disruption of hippocampal PTP1B function or expression leads to elongation of dendritic filopodia and improved learning and memory, demonstrating an exciting novel role for this phosphatase.

  5. EFFECTS OF INQUIRY TRAINING LEARNING MODEL BASED MULTIMEDIA AND MOTIVATION OF PHYSICS STUDENT LEARNING OUTCOMES

    OpenAIRE

    Hayati .; Retno Dwi Suyanti

    2013-01-01

    The objective in this research: (1) Determine a better learning model to improve learning outcomes physics students among learning model Inquiry Training based multimedia and Inquiry Training learning model. (2) Determine the level of motivation to learn in affects physics student learning outcomes. (3) Knowing the interactions between the model of learning and motivation in influencing student learning outcomes. This research is a quasi experimental. The population in this research was all s...

  6. D2.1 - An EA Active, Problem Based Learning Methodology - EAtrain2

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Georgsen, Marianne; Buus, Lillian

    This deliverable reports on the work undertaken in work package 2 with the key objective to develop a learning methodology for web 2.0 mediated Enterprise Architecture (EA) learning building on a problem based learning (PBL) approach. The deliverable reports not only on the methodology but also...... on the activities leading to its development (literature review, workshops, etc.) and on further outcomes of this work relevant to the platform specification and pilot courses preparation....

  7. ERP correlates of associative learning.

    Science.gov (United States)

    Rose, M; Verleger, R; Wascher, E

    2001-05-01

    We examined changes of event-related potentials (ERPs) while participants learned stimulus-to-stimulus relations in an S1-S2 task. The design allowed for separating processes of associative learning from nonspecific effects. Participants had to respond to S2 by a left or right key-press dependent on S2 identity (letter W or M). Preparation for S2 could be improved by using the associative information given by S1. The S1 was an arrow pointing to the left or right. In combination with its color, arrow direction was informative about location and identity of S2, but participants were not informed about the relevance of color. Arrows in two of the colors were fully predictive for the S2 whereas the third color gave no valid information. This third stimulus controlled for habituation and procedural learning. Six blocks with 200 trials each and all three S1 colors in random order were presented. Behavioral and ERP differences in each block between "learning" and control trials were used to identify processes of associative learning. Several effects of associative learning were identified indicating the involvement of specific stages of information processing: a continuous increase of P3 amplitude evoked by S1 was accompanied by a decrease of P3 evoked by S2. These changes reflected the modifications of stimulus weights for response selection and the strengthened association between the two stimulus complexes in the time course of learning. The related motor preparation benefited from learning too, expressed in a decrease of CNV amplitude and an increase of LRP amplitude. Finally a decrease of N1 amplitude evoked by S2 indicated the reduced need to allocate spatial attention to the S2 location according to the learned meaning of S1.

  8. Development and Evaluation of a Computer-Based Learning Environment for Teachers: Assessment of Learning Strategies in Learning Journals

    Directory of Open Access Journals (Sweden)

    Inga Glogger

    2013-01-01

    Full Text Available Training teachers to assess important components of self-regulated learning such as learning strategies is an important, yet somewhat neglected, aspect of the integration of self-regulated learning at school. Learning journals can be used to assess learning strategies in line with cyclical process models of self-regulated learning, allowing for rich formative feedback. Against this background, we developed a computer-based learning environment (CBLE that trains teachers to assess learning strategies with learning journals. The contents of the CBLE and its instructional design were derived from theory. The CBLE was further shaped by research in a design-based manner. Finally, in two evaluation studies, student teachers (N1=44; N2=89 worked with the CBLE. We analyzed satisfaction, interest, usability, and assessment skills. Additionally, in evaluation study 2, effects of an experimental variation on motivation and assessment skills were tested. We found high satisfaction, interest, and good usability, as well as satisfying assessment skills, after working with the CBLE. Results show that teachers can be trained to assess learning strategies in learning journals. The developed CBLE offers new perspectives on how to support teachers in fostering learning strategies as central component of effective self-regulated learning at school.

  9. Self-Play and Using an Expert to Learn to Play Backgammon with Temporal Difference Learning

    NARCIS (Netherlands)

    Wiering, Marco A.

    2010-01-01

    A promising approach to learn to play board games is to use reinforcement learning algorithms that can learn a game position evaluation function. In this paper we examine and compare three different methods for generating training games: 1) Learning by self-play, 2) Learning by playing against an

  10. A INFLUÊNCIA DO CAMPUS DO VALE DA UFRGS NA URBANIZAÇÃO DO SEU ENTORNO A PARTIR DA PERSPECTIVA DOS MORADORES DO BAIRRO SANTA ISABEL, VIAMÃO/RS

    Directory of Open Access Journals (Sweden)

    Joseli Andrades Maia

    2016-09-01

    Full Text Available Desde a sua criação, a função das Universidades tem evoluído: de uma instituição de ensino formal a uma agente criadora e modeladora de espaços, atraindo a população não acadêmica para o seu entorno e auxiliando na produção e orientação do uso do solo no qual está inserida. A presente pesquisa analisou parte do bairro viamonense Santa Isabel, especialmente a vila Jardim Universitário, localizado na divisa com o Campus do Vale da Universidade Federal do Rio Grande do Sul (UFRGS, este em Porto Alegre (POA. Partindo da questão se o Campus do Vale influenciou na expansão da urbanização do seu entorno, os principais instrumentos de coleta de dados foram a entrevista e o questionário com os moradores locais, totalizando 354 pessoas. Segundo 62,7% desses, a UFRGS foi responsável pela expansão da urbanização. Embora quantitativamente os valores encontrados apontem essa responsabilidade ao campus, outros fatores também foram importantes, como o caso do valor do uso do solo. Em um primeiro momento o bairro se constituiu como uma alternativa viável para a residência, devido o preço dos lotes e a localização próxima à capital, beneficiando aqueles que trabalhavam em POA. Em um segundo momento, no final da década de 1970 – a partir da construção do Campus do Vale – observou-se a expansão da urbanização com o aumento da população e a redução de áreas vazias para dar espaço à construção civil. Em campo analisou-se a grande relação que há entre moradores e os pontos de serviços oferecidos nas dependências da universidade, como é o caso do terminal de ônibus, agências bancárias e farmácia, além de gerar empregos e valorizar os imóveis próximos, dada a importância do aluguel para os estudantes.

  11. For People with Osteoporosis: How to Find a Doctor

    Science.gov (United States)

    ... With Osteoporosis: How to Find a Doctor For People With Osteoporosis: How to Find a Doctor Isabel ... a doctor with expertise in osteoporosis. For many people, finding a doctor who is knowledgeable about osteoporosis ...

  12. The development of learning material using learning cycle 5E model based stem to improve students’ learning outcomes in Thermochemistry

    Science.gov (United States)

    sugiarti, A. C.; suyatno, S.; Sanjaya, I. G. M.

    2018-04-01

    The objective of this study is describing the feasibility of Learning Cycle 5E STEM (Science, Technology, Engineering, and Mathematics) based learning material which is appropriate to improve students’ learning achievement in Thermochemistry. The study design used 4-D models and one group pretest-posttest design to obtain the information about the improvement of sudents’ learning outcomes. The subject was learning cycle 5E based STEM learning materials which the data were collected from 30 students of Science class at 11th Grade. The techniques used in this study were validation, observation, test, and questionnaire. Some result attain: (1) all the learning materials contents were valid, (2) the practicality and the effectiveness of all the learning materials contents were classified as good. The conclution of this study based on those three condition, the Learnig Cycle 5E based STEM learning materials is appropriate to improve students’ learning outcomes in studying Thermochemistry.

  13. An Experiment on How Adult Students Can Learn by Designing Engaging Learning Games

    DEFF Research Database (Denmark)

    Weitze, Charlotte Lærke

    2014-01-01

    worth investigating as a motivational learning strategy. As meaning can be constructed through the manipulation of materials, which facilitates reflection and new ways of thinking, the use of learning games in education is taken one step further into the building of learning games in collaborative...... enables the students to be the designers of their own learning, by allowing them to create their own digital learning games, while implementing learning goals from cross-disciplinary subject matters (Figure 1). Another focus has been to create a learning design that scaffolds the students’ own learning-game......This article presents and discusses the first iteration of a design-based research experiment focusing on how to create a motivating gamified learning design, one that facilitates a deep learning process for adult students making their own learning games. Using games for learning has attracted...

  14. Involvement of Dopamine D1/D5 and D2 Receptors in Context-Dependent Extinction Learning and Memory Reinstatement.

    Science.gov (United States)

    André, Marion Agnès Emma; Manahan-Vaughan, Denise

    2015-01-01

    Dopamine contributes to the regulation of higher order information processing and executive control. It is important for memory consolidation processes, and for the adaptation of learned responses based on experience. In line with this, under aversive learning conditions, application of dopamine receptor antagonists prior to extinction result in enhanced memory reinstatement. Here, we investigated the contribution of the dopaminergic system to extinction and memory reinstatement (renewal) of an appetitive spatial learning task in rodents. Rats were trained for 3 days in a T-maze (context "A") to associate a goal arm with a food reward, despite low reward probability (acquisition phase). On day 4, extinction learning (unrewarded) occurred, that was reinforced by a context change ("B"). On day 5, re-exposure to the (unrewarded) "A" context took place (renewal of context "A", followed by extinction of context "A"). In control animals, significant extinction occurred on day 4, that was followed by an initial memory reinstatement (renewal) on day 5, that was, in turn, succeeded by extinction of renewal. Intracerebral treatment with a D1/D5-receptor antagonist prior to the extinction trials, elicited a potent enhancement of extinction in context "B". By contrast, a D1/D5-agonist impaired renewal in context "A". Extinction in the "A" context on day 5 was unaffected by the D1/D5-ligands. Treatment with a D2-receptor antagonist prior to extinction had no overall effect on extinction in context "B" or renewal in context "A", although extinction of the renewal effect was impaired on day 5, compared to controls. Taken together, these data suggest that dopamine acting on the D1/D5-receptor modulates both acquisition and consolidation of context-dependent extinction. By contrast, the D2-receptor may contribute to context-independent aspects of this kind of extinction learning.

  15. ANALISIS DESKRIPTIF DALAM PENERAPAN MODEL PEMBELAJARAN PBL (PROBLEM BASED LEARNING OLEH GURU MATA PELAJARAN EKONOMI SMA NEGERI 1 SLIYEG KABUPATEN INDRAMAYU

    Directory of Open Access Journals (Sweden)

    Sheilla Az Zahra

    2015-06-01

    Full Text Available Permasalahan dalam penelitian ini antara lain : (1 Perencanaan pembelajaran PBL oleh guru Ekonomi (2 Pelaksanaan pembelajaran PBL oleh guru Ekonomi di SMAN 1 Sliyeg (3 Evaluasi pembelajaran PBL oleh guru Ekonomi. Metode yang digunakan dalam penelitian ini adalah metode kualitatif. Penelitian ini dilaksanakan di SMA Negeri 1 Sliyeg Kabupaten Indramayu. Alat analisis data adalah analisis interaksi. Teknik pengumpulan data menggunakan wawancara dan dokumentasi. Informan utama adalah guru mata pelajaran Ekonomi. Teknik analisis data dalam penelitian ini meliputi : pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan atau verifikasi data. Hasil penelitian menunjukkan bahwa guru-guru mata pelajaran Ekonomi di SMAN 1 Sliyeg selalu membuat perangkat pembelajaran di awal semester dan selalu menyusun dan mempersiapkan RPP sebelum mengajar. Pelaksanaan pembelajaran PBL oleh guru Ekonomi sudah cukup baik dan guru pun cukup memahami mengenai PBL dan mendapat respon positif dari siswa. Evaluasi dan penilaian dari guru Ekonomi masing-masing mempunyai cara yang berbeda, seperti quiz dan tanya jawab, lalu guru memberi nilai tambahan kepada siswa yang aktif dalam menjawab. Saran yang diberikan dalam penelitian ini adalah guru sebaiknya meningkatkan pemahaman mengenai pembelajaran PBL. Guru harus lebih berwawasan luas, meningkatkan kretivitas dan inovatif dalam pelaksanaan PBL. Guru harus memperluas wawasan dan lebih kreatif lagi dalam mengembangkan cara evaluasi pada akhir pembelajaran. One of these models is the learning of model PBL (Problem Based Learning. It is expected that a better model of PBL to increase student activity when compared with the model konvesional.So far this learning process is still dominated by a paradigm that states that a knowledge of the facts is to be memorized. Problems in this study include: (1 Planning of PBL learning by teachers of Economics (2 The implementation of PBL learning by Economics teacher at SMAN 1

  16. D.3.1 PLOT Persuasive Learning Design Framework

    DEFF Research Database (Denmark)

    Gram-Hansen, Sandra Burri; Schärfe, Henrik; Dinesen, Jens Vilhelm

    2011-01-01

    offer examples of central issues in learning theories can be aligned with persuasive efforts as seen from a rhetorical point of view. In section 3, we continue the work of defining intersections between persuasion and didactics, where more specifically oriented towards the notions of kairos...

  17. Doña Mencía de Mendoza y su residencia en el Palacio del Real en Valencia

    Directory of Open Access Journals (Sweden)

    Hidalgo Ogáyar, Juana

    2011-03-01

    Full Text Available Documents preserved in the Archivo del Palau reveal the furnishings that Mencía de Mendoza had in the Royal Palace at Valencia, particularly luxury beds such as those of the Empress Isabel of Portugal and Queen Mary of France. Painters active at her court, especially Juan de Bolaños, are also discussed.

    Con la ayuda de varios documentos conservados en el Archivo del Palau, se dan a conocer diferentes enseres que Doña Mencía de Mendoza tenía en el Palacio del Real en Valencia, destacando camas de lujo como la de la Emperatriz Isabel de Portugal o la de María de Francia. Se dan a conocer algunos pintores activos en su corte como Juan de Bolaños.

  18. Learning of Grammar-Like Visual Sequences by Adults with and without Language-Learning Disabilities

    Science.gov (United States)

    Aguilar, Jessica M.; Plante, Elena

    2014-01-01

    Purpose: Two studies examined learning of grammar-like visual sequences to determine whether a general deficit in statistical learning characterizes this population. Furthermore, we tested the hypothesis that difficulty in sustaining attention during the learning task might account for differences in statistical learning. Method: In Study 1,…

  19. IMPACT OF INFORMATION SERVICES USING MEDIA FILM TO STUDENT MOTIVATION LEARNING AT SMA NEGERI 1 RAMAN UTARA, LAMPUNG TIMUR

    Directory of Open Access Journals (Sweden)

    Septazema Suciana

    2014-09-01

    Full Text Available Abstract: One of the factors that can influence student learning is the motivation to learn. Students' motivation can be built with an understanding to students about the importance of learning how to learn effectively, and how to overcome learning problems. Departing from this, the research problem is formulated as follows: Is there any influence of information services on the students motivation ?. The aim of research to determine the effect of information services on the students motivation. The study design was one group pretest-posttest design. Subjects numbered 20 students. To determine the study subjects used the technique Proportionate Stratified Random Sampling.Hasil hypothesis test showed the value of t = 8.75> 1.729. The conclusion of the study is an information service that executed can affect motivation. Therefore, it is advisable to guidance and counseling teachers use information services by using the medium of film, so that the services effectively organized and able to enhance students' motivation. Keyword: Information Services, Motivation

  20. Learning of grammar-like visual sequences by adults with and without language-learning disabilities.

    Science.gov (United States)

    Aguilar, Jessica M; Plante, Elena

    2014-08-01

    Two studies examined learning of grammar-like visual sequences to determine whether a general deficit in statistical learning characterizes this population. Furthermore, we tested the hypothesis that difficulty in sustaining attention during the learning task might account for differences in statistical learning. In Study 1, adults with normal language (NL) or language-learning disability (LLD) were familiarized with the visual artificial grammar and then tested using items that conformed or deviated from the grammar. In Study 2, a 2nd sample of adults with NL and LLD were presented auditory word pairs with weak semantic associations (e.g., groom + clean) along with the visual learning task. Participants were instructed to attend to visual sequences and to ignore the auditory stimuli. Incidental encoding of these words would indicate reduced attention to the primary task. In Studies 1 and 2, both groups demonstrated learning and generalization of the artificial grammar. In Study 2, neither the NL nor the LLD group appeared to encode the words presented during the learning phase. The results argue against a general deficit in statistical learning for individuals with LLD and demonstrate that both NL and LLD learners can ignore extraneous auditory stimuli during visual learning.

  1. Learning design thinking online : studying students' learning experience in shared virtual reality

    OpenAIRE

    Lau, Kung Wong

    2010-01-01

    Learning Design Thinking Online: Studying Students' Learning Experience in Shared Virtual Reality My study attempts to deepen understanding about the learning experiences of design students in undertaking design-thinking exercises in a shared virtual reality. This study has identified the areas of an appropriate pedagogy for E-Learning and the use of a shared virtual environment for students in tertiary design education. Specific questions arising ji"Om this research are: (1...

  2. Evaluasi Tingkat Kematangan Proses Pengelolaan Data Pada Sistem Informasi E-Learning SMKN 1 Jenangan Menggunakan Cobit Quickstart

    Directory of Open Access Journals (Sweden)

    Dwiyono Ariyadi

    2016-05-01

    Full Text Available SMKN 1 Jenangan telah mengadopsi TI sebagai sarana pendukung kegiatan pendidikan, salah satunya adalah e-learning sebagai sarana penunjang kegiatan pembelajaran. Pengelolaan manajemen data e-learning ini merupakan hal penting karena data sangat diperlukan dalam administrasi harian guru bahkan juga untuk keperluan administrasi akreditasi. Saat ini pengelolaan manajemen data masih belum optimal, hal ini terlihat guru sering kehilangan data e-learning-nya saat terjadi perbaikan sistem. Backupan data belum dilakukan oleh sebagian besar guru sebagai pengguna e-learning. Perlu adanya suatu perencanaan tata kelola TI yang diharapkan dapat menjadi dasar dalam pengelolaan sistem e-learning di sekolah tersebut, sehingga e-learning ini bisa berjalan optimal sesuai yang diharapkan. COBIT merupakan framework yang bisa digunakan untuk menyusun Tata kelola TI maupun melaksanakan audit TI yang telah diakui secara internasional. Versi yang sederhana adalah COBIT Quickstart. Penelitian ini menggunakan model tingkat kematangan yang bertujuan untuk memperoleh data kondisi aktual pada domain DS 11(mengelola data dengan mempertimbangkan nilai indek kematangan (maturity index pada 6 atribut kematangan yaitu: Awareness and Communication (AC, Policies, Standards and Procedures (PSP, Tools and Automation (TA, Skill and Expertise (SE. Responsibilities and Accountabilities (RA, Goal Setting and Measurement (GSM. Kondisi saat ini (as-is terdapat tiga atribut berada pada level 1(inisialisasi, yaitu atribut RA, GSM dan AC, sedangkan lainnya sudah berada pada level dua(dapat diulang. Ini tergambar dengan kondisi sebagai berikut : peran dan tanggungjawab dalam manajemen data server belum ada kejelasan, kegiatan pengawasan terkait keamanan, backup data serta penghapusan data belum dilaksanankan, serta kesadaran terkait proses DS 11 baru sebagian pengguna SI yang peduli. Rekomendasi tindakan perbaikan merupakan proses perbaikan secara alamiah, serta merupakan proses pembelajaran

  3. Problem Based Learning

    DEFF Research Database (Denmark)

    de Graaff, Erik; Guerra, Aida

    , the key principles remain the same everywhere. Graaff & Kolmos (2003) identify the main PBL principles as follows: 1. Problem orientation 2. Project organization through teams or group work 3. Participant-directed 4. Experiental learning 5. Activity-based learning 6. Interdisciplinary learning and 7...... model and in general problem based and project based learning. We apply the principle of teach as you preach. The poster aims to outline the visitors’ workshop programme showing the results of some recent evaluations.......Problem-Based Learning (PBL) is an innovative method to organize the learning process in such a way that the students actively engage in finding answers by themselves. During the past 40 years PBL has evolved and diversified resulting in a multitude in variations in models and practices. However...

  4. THE EFFECTS OF COOPERATIVE LEARNING MODEL GROUP INVESTIGATION AND MOTIVATION TOWARD PHYSICS LEARNING RESULTS MAN TANJUNGBALAI

    Directory of Open Access Journals (Sweden)

    Amalia Febri Aristi

    2014-12-01

    Full Text Available This study aimed to determine: (1 Is there a difference in student's learning outcomes with the application of learning models Investigation Group and Direct Instruction teaching model. (2 Is there a difference in students' motivation with the application of learning models Investigation Group and Direct Instruction teaching model, (3 Is there an interaction between learning models Investigation Group and Direct Instruction to improve students' motivation in learning outcomes Physics. This research is a quasi experimental. The study population was a student of class XII Tanjung Balai MAN. Random sample selection is done by randomizing the class. The instrument used consisted of: (1 achievement test (2 students' motivation questionnaire. The tests are used to obtain the data is shaped essay. The data in this study were analyzed using ANOVA analysis of two paths. The results showed that: (1 there were differences in learning outcomes between students who used the physics model of Group Investigation learning compared with students who used the Direct Instruction teaching model. (2 There was a difference in student's learning outcomes that had a low learning motivation and high motivation to learn both in the classroom and in the classroom Investigation Group Direct Instruction. (3 There was interaction between learning models Instruction Direct Group Investigation and motivation to learn in improving learning outcomes Physics.

  5. Repurposeable Learning Objects Linked to Teaching and Learning Styles

    Directory of Open Access Journals (Sweden)

    Jeremy Dunning

    2004-02-01

    Full Text Available Multimedia learning objects are an essential component of high quality, technology-mediated instruction. Learning objects allow the student to use the content learned in a particular part of a course and; 1. demonstrate mastery of the content, 2. apply that knowledge to solving a problem, and 3. use the content in a critical thinking exercise that both demonstrates mastery and allows the student to place the content within the context of the larger topic of the course. The difficulty associated with the use of learning objects on a broad scale is that they require programming skills most professors and instructors do not possess. Learning objects also tend to be custom productions and are defined in terms of the programming and code terminology, further limiting the professor's ability to understand how they are created. Learning objects defined in terms of styles of learning and teaching allow professors and instructors to develop a deeper understanding of the learning objects and the design process. A set of learning objects has been created that are designed for some of the important styles of learning and teaching. They include; visual learning, writing skills, critical thinking, time-revealed scenarios, case studies and empirical observation. The learning objects are designed and described in terms that the average instructor can readily understand , redesign and incorporate into their own courses. They are also designed in such a way that they can readily be repurposed for new applications in other courses and subject areas, with little or no additional programming.

  6. Project- Based Learning and Problem-Based Learning: Are They Effective to Improve Student's Thinking Skills?

    OpenAIRE

    Anazifa, R. D; Djukri, D

    2017-01-01

    The study aims at finding (1) the effect of project-based learning and problem-based learning on student's creativity and critical thinking and (2) the difference effect of project-based learning and problem-based learning on student's creativity and critical thinking. This study is quasi experiment using non-equivalent control-group design. Research population of this study was all classes in eleventh grade of mathematics and natural science program of SMA N 1 Temanggung. The participants we...

  7. RELATIONSHIP OF INTEREST, LEARNING MOTIVATION AND ATTITUDE WITH RESULTS LEARNING CLASS VIII SMP STATE 13 MAKASSAR

    Directory of Open Access Journals (Sweden)

    Putri Athirah Azis

    2016-12-01

    Full Text Available The study aims at examining (1 the correlation of learning interest towards learning result of grade students, (2 the correlation of learning motivation towards learning result of grade students, (3 the correlation of students attitude towards learning result, (4 the correlationof interest, learning motivation, and attitude collaboratively towards learning result. The study is an ex post facto. The population of the study was grade VIII at SMPN 13 Makassar. Samples were 105 students taken by employing random sampling technique. Data were collected through questionnaire and documentation. Data were analyzed using regression test. The result of study reveal that (1 there is significant correlation (p<0,01 of interest towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,718 and its effectiveness contribution (R2 is 51,5%, (2 there is significant correlation (p<0,01 of motivation towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,775 and its effectiveness contribution (R2 is 60,1%, (3 there is significant correlation (p<0,01 of attitude towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,737 and its effectiveness contribution (R2 is 54,4%, (4 there is significant correlation (p<0,01 of interest, motivation and attitude collaboratively towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,861 and its effectiveness contribution (R2 is 74,1%,

  8. Learning How to Learn

    DEFF Research Database (Denmark)

    Lauridsen, Karen M.; Lauridsen, Ole

    Ole Lauridsen, Aarhus School of Business and Social Sciences, Aarhus University, Denmark Karen M. Lauridsen, Aarhus School of Business and Social Sciences, Aarhus University, Denmark Learning Styles in Higher Education – Learning How to Learn Applying learning styles (LS) in higher education...... by Constructivist learning theory and current basic knowledge of how the brain learns. The LS concept will thus be placed in a broader learning theoretical context as a strong learning and teaching tool. Participants will be offered the opportunity to have their own LS preferences established before...... teaching leads to positive results and enhanced student learning. However, learning styles should not only be considered a didactic matter for the teacher, but also a tool for the individual students to improve their learning capabilities – not least in contexts where information is not necessarily...

  9. PENGGUNAAN MODEL PROBLEM BASED LEARNING BERBANTUAN E-LEARNING TERHADAP KEMANDIRIAN BELAJAR MAHASISWA

    Directory of Open Access Journals (Sweden)

    Jusep Saputra

    2017-11-01

    Full Text Available Self-regulated learning of learners can be achieved, if in the process of learning mathematics provides an open opportunity for students to learn independently. This research is a mixed method type embedded design, which aims to do studies focused on the use of the Problem Based Learning (PBL model assisted e-learning to student self-regulated learning. Sample selection is done on the purposive sampling and was taken 2 class contracting courses of school math III. Class A numbered 50 members, 24 the superior group and 26 the low group, given the treatment with PBL models assisted e-learning and class B numbered 50, 27 the superior group and 23 the low group, with expository. Instruments used in this research is self-regulated learning questionnaire with Likert scale. Based on data analysis we concluded that (1 Self-regulated learning of superior and low student who obtains aided PBL models assisted e-learning is better than self-regulated learning of superior and low superior students who obtain expository.

  10. Brief Overview of Motor Learning and It's Application to Rehabilitation: Part Ⅰ: Motor Learning Theory

    Institute of Scientific and Technical Information of China (English)

    Christopher A Zaino

    2003-01-01

    @@ 1 DEFINITION OF MOTOR LEARNING Motor learning is the study of how we acquire and modify movements.1 The acquisition of motor skills is the process of learning how to do a particular movement (performance), but the real key to therapeutic intervention is being able to affect permanent changes in motor skills via the process of motor learning. Therefore, motor learning is defined as the ability to retain the ability to perform a motor task at a later time. In rehabilitation, it is important to be cognizant of the concepts of acquisition and retention. We can facilitate acquisition,but do little to assist in the retention of the task (learning). Conversely, we can arrange practice such that acquisition is slowed, but we can actually be assisting learning the task. It is important to have a clear goal in mind and work towards the eventual learning of the task to allow full functional use of that skill.

  11. Attitude to e-learning among newly qualified doctors.

    Science.gov (United States)

    Goh, Jason; Clapham, Michael

    2014-02-01

    e-Learning plays an increasingly important role in medical education. Much research has focused on the evaluation of individual modules among medical students or more senior trainee doctors. We studied the attitude of newly qualified foundation level-1 doctors (FY1s) towards a blended learning programme to gain insight into the perceived role of e-learning in relation to classroom and experiential learning. The blended learning strategy consisted of weekly 3-hour sessions of lectures and flexible e-learning sessions. A questionnaire survey was conducted among 54 per cent (37/69) of FY1 doctors, towards the end of their first year post qualification. The majority of FY1s had to carry out additional e-learning outside of work. When asked where was best to carry out e-learning, 54 per cent preferred to e-learn both at work and at home, whereas 38 per cent preferred to e-learn outside of work exclusively. An equal preference for a classroom-only strategy and a blended programme was reported. Seventy-three per cent of the FY1s thought that e-learning should not be part of their compulsory weekly teaching programme. Fifty-four per cent of FY1s thought that e-learning had been useful for their education and training in their FY1 year. The e-learning package cited as being most useful was the safe prescribing e-programme, pioneered locally. Newly qualified doctors value e-learning as an adjunct to experiential and lecture-based teaching, and most prefer it as part of a blended learning programme at work or at home. Medical educators must place equal emphasis on the delivery and administration of e-learning as well as on the course design. © 2014 John Wiley & Sons Ltd.

  12. The role of trigeminal nucleus caudalis orexin 1 receptors in orofacial pain transmission and in orofacial pain-induced learning and memory impairment in rats.

    Science.gov (United States)

    Kooshki, Razieh; Abbasnejad, Mehdi; Esmaeili-Mahani, Saeed; Raoof, Maryam

    2016-04-01

    It is widely accepted that the spinal trigeminal nuclear complex, especially the subnucleus caudalis (Vc), receives input from orofacial structures. The neuropeptides orexin-A and -B are expressed in multiple neuronal systems. Orexin signaling has been implicated in pain-modulating system as well as learning and memory processes. Orexin 1 receptor (OX1R) has been reported in trigeminal nucleus caudalis. However, its roles in trigeminal pain modulation have not been elucidated so far. This study was designed to investigate the role of Vc OX1R in the modulation of orofacial pain as well as pain-induced learning and memory deficits. Orofacial pain was induced by subcutaneous injection of capsaicin in the right upper lip of the rats. OX1R agonist (orexin-A) and antagonist (SB-334867-A) were microinjected into Vc prior capsaicin administration. After recording nociceptive times, learning and memory was investigated using Morris water maze (MWM) test. The results indicated that, orexin-A (150 pM/rat) significantly reduced the nociceptive times, while SB334867-A (80 nM/rat) exaggerated nociceptive behavior in response to capsaicin injection. In MWM test, capsaicin-treated rats showed a significant learning and memory impairment. Moreover, SB-334867-A (80 nM/rat) significantly exaggerated learning and memory impairment in capsaicin-treated rats. However, administration of orexin-A (100 pM/rat) prevented learning and memory deficits. Taken together, these results indicate that Vc OX1R was at least in part involved in orofacial pain transmission and orexin-A has also a beneficial inhibitory effect on orofacial pain-induced deficits in abilities of spatial learning and memory. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Theoretical assumptions of Maffesoli's sensitivity and Problem-Based Learning in Nursing Education1

    Science.gov (United States)

    Rodríguez-Borrego, María-Aurora; Nitschke, Rosane Gonçalves; do Prado, Marta Lenise; Martini, Jussara Gue; Guerra-Martín, María-Dolores; González-Galán, Carmen

    2014-01-01

    Objective understand the everyday and the imaginary of Nursing students in their knowledge socialization process through the Problem-Based Learning (PBL) strategy. Method Action Research, involving 86 students from the second year of an undergraduate Nursing program in Spain. A Critical Incident Questionnaire and Group interview were used. Thematic/categorical analysis, triangulation of researchers, subjects and techniques. Results the students signal the need to have a view from within, reinforcing the criticism against the schematic dualism; PBL allows one to learn how to be with the other, with his mechanical and organic solidarity; the feeling together, with its emphasis on learning to work in group and wanting to be close to the person taking care. Conclusions The great contradictions the protagonists of the process, that is, the students experience seem to express that group learning is not a form of gaining knowledge, as it makes them lose time to study. The daily, the execution time and the imaginary of how learning should be do not seem to have an intersection point in the use of Problem-Based Learning. The importance of focusing on the daily and the imaginary should be reinforced when we consider nursing education. PMID:25029064

  14. Effects of prior knowledge on learning from different compositions of representations in a mobile learning environment

    NARCIS (Netherlands)

    T.-C. Liu (Tzu-Chien); Y.-C. Lin (Yi-Chun); G.W.C. Paas (Fred)

    2014-01-01

    textabstractTwo experiments examined the effects of prior knowledge on learning from different compositions of multiple representations in a mobile learning environment on plant leaf morphology for primary school students. Experiment 1 compared the learning effects of a mobile learning environment

  15. Learning and liking of melody and harmony: further studies in artificial grammar learning.

    Science.gov (United States)

    Loui, Psyche

    2012-10-01

    Much of what we know and love about music is based on implicitly acquired mental representations of musical pitches and the relationships between them. While previous studies have shown that these mental representations of music can be acquired rapidly and can influence preference, it is still unclear which aspects of music influence learning and preference formation. This article reports two experiments that use an artificial musical system to examine two questions: (1) which aspects of music matter most for learning, and (2) which aspects of music matter most for preference formation. Two aspects of music are tested: melody and harmony. In Experiment 1 we tested the learning and liking of a new musical system that is manipulated melodically so that only some of the possible conditional probabilities between successive notes are presented. In Experiment 2 we administered the same tests for learning and liking, but we used a musical system that is manipulated harmonically to eliminate the property of harmonic whole-integer ratios between pitches. Results show that disrupting melody (Experiment 1) disabled the learning of music without disrupting preference formation, whereas disrupting harmony (Experiment 2) does not affect learning and memory but disrupts preference formation. Results point to a possible dissociation between learning and preference in musical knowledge. Copyright © 2012 Cognitive Science Society, Inc.

  16. Budgeted Interactive Learning

    Science.gov (United States)

    2017-06-15

    2, and 3). The selection scheme is implemented and released as an open-source active learning package. They have studied theories for designing...We have studied theories for designing algorithms for interactive learning with batch-like feedback (for 1) and algorithms for online digestion of... necessity on pre-training. The new idea provides layer-wise cost estimation with auxiliary nodes, and is applicable to a wider range of deep learning

  17. The Effect of Implementing the Experiential Learning Model in Listening Comprehension for the Eleventh Graders at SMAN 1 Telaga Biru

    Directory of Open Access Journals (Sweden)

    Ismail Tahir

    2017-11-01

    Full Text Available This study is aimed to investigate the effectiveness of the experiential learning in listening comprehension with the focus on the implementation of the class story using language experience at SMAN 1 Telaga Biru. As the pre-experimental research, this study involved one class consisted of 27 students in the eleventh graders. However, most of the students of the eleventh graders in this school have some problems in their listening comprehension. This current research, therefore, aims at finding the result of the students’ listening comprehension by using experiential learning in focusing on the class story using language experience for the eleventh graders at SMAN 1 Telaga Biru and defining the students’ achievement in listening comprehension by using experiential learning focusing on the class story using language experience.  This study also explored the learners’ listening comprehension by analyzing the result of the students’ pre-test and post-test. It was found that the mean of the pre-test was 60 while the mean of the post-test was 80,6. By analyzing this result, it indicated that the post-test was higher than the pre-test. In conclusion, the finding of this research showed that teaching listening in the eleventh graders of SMAN 1 Telaga Biru using experiential learning in focusing on the class story using language experience was effective to teach students’ listening comprehension. Therefore, it can be suggested that it was an alternative way to use of experiential learning focusing on the class story using language experience in teaching listening.

  18. Learning to Learn.

    Science.gov (United States)

    Weiss, Helen; Weiss, Martin

    1988-01-01

    The article reviews theories of learning (e.g., stimulus-response, trial and error, operant conditioning, cognitive), considers the role of motivation, and summarizes nine research-supported rules of effective learning. Suggestions are applied to teaching learning strategies to learning-disabled students. (DB)

  19. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on e-Learning (Madeira, Portugal, July 1-4, 2016)

    Science.gov (United States)

    Nunes, Miguel Baptista, Ed.; McPherson, Maggie, Ed.

    2016-01-01

    These proceedings contain the papers of the International Conference e-Learning 2016, which was organised by the International Association for Development of the Information Society, 1-3 July, 2016. This conference is part of the Multi Conference on Computer Science and Information Systems 2016, 1-4 July. The e-Learning (EL) 2016 conference aims…

  20. Flipped Learning

    DEFF Research Database (Denmark)

    Holmboe, Peter; Hachmann, Roland

    I FLIPPED LEARNING – FLIP MED VIDEO kan du læse om, hvordan du som underviser kommer godt i gang med at implementere video i undervisning, der har afsæt i tankerne omkring flipped learning. Bogen indeholder fire dele: I Del 1 fokuserer vi på det metarefleksive i at tænke video ind i undervisningen...

  1. Machine Learning

    Energy Technology Data Exchange (ETDEWEB)

    Chikkagoudar, Satish; Chatterjee, Samrat; Thomas, Dennis G.; Carroll, Thomas E.; Muller, George

    2017-04-21

    The absence of a robust and unified theory of cyber dynamics presents challenges and opportunities for using machine learning based data-driven approaches to further the understanding of the behavior of such complex systems. Analysts can also use machine learning approaches to gain operational insights. In order to be operationally beneficial, cybersecurity machine learning based models need to have the ability to: (1) represent a real-world system, (2) infer system properties, and (3) learn and adapt based on expert knowledge and observations. Probabilistic models and Probabilistic graphical models provide these necessary properties and are further explored in this chapter. Bayesian Networks and Hidden Markov Models are introduced as an example of a widely used data driven classification/modeling strategy.

  2. Proceedings - II Nanosciesce and Nanotecnology Biomedicals Symposium

    OpenAIRE

    Luís Monteiro Rodrigues et al; Isabel V. Figueiredo

    2013-01-01

    Programa Open Session | Sessão de abertura Pres. do Conselho de Admin. do INFARMED, Dr. Eurico Castro Alves Pres. do Conselho de Admin. da Univ Lusófona, Manuel de A. Damásio Diretor da Escola de Ciências e Tecnologias da Saúde Luís Monteiro Rodrigues (Presidente do Simpósio) Presidente da Sociedade Portuguesa de Ciências em Animais de Laboratório, Isabel V. Figueiredo 1st Session |Sessão 1 Nanomedicine: past and future | Nanomedicina: passado e futuro Chairman |...

  3. The Managers’ Experiential Learning of Program Planning in Active Ageing Learning Centers

    Directory of Open Access Journals (Sweden)

    Chun-Ting Yeh

    2016-12-01

    Full Text Available Planning older adult learning programs is really a complex work. Program planners go through different learning stages and accumulate experiences to be able to undertake the task alone. This study aimed to explore the experiential learning process of older adult learning program planners who work in the Active Ageing Learning Centers (AALCs. Semi-structure interviews were conducted with seven program planners. The findings of this study were identified as follows. 1 Before being a program planner, the participants’ knowledge results from grasping and transforming experience gained from their family, their daily lives and past learning experiences; 2 after being a program planner, the participants’ experiential learning focused on leadership, training in the institute, professional development, as well as involvement in organizations for elderly people; and 3 the participants’ experiential learning outcomes in the older adult learning program planning include: their ability to reflect on the appropriateness and fulfillment of program planning, to apply theoretical knowledge and professional background in the field, and to make plans for future learning and business strategies.

  4. Os desenhos animados e as crianças : um estudo multicaso sobre as preferências de desenhos animados por crianças do 1º ciclo do ensino básico

    OpenAIRE

    Morais, Sandra Araújo Martins

    2008-01-01

    Dissertação de mestrado em Estudos da Criança (área de especialização em Tecnologias de Informação e Comunicação) Em diversos estudos efectuados, nomeadamente no de Bredorode Santos (1991), Sara Pereira (2002) e Ana Maria Magalhães e Isabel Alçada (1993), as crianças indicam os desenhos animados como a programação específica na qual costumam despender mais tempo de visionamento, quer durante a semana, quer ao fim-de-semana. Todavia, a partir da revisão da literatura, verifi...

  5. Flipped learning: should it replace didactic learning?

    Directory of Open Access Journals (Sweden)

    Osman A

    2017-10-01

    Full Text Available Abdirahman Osman, Seyed Ramin Jalal, Saeed Azizi Faculty of Medicine, St George’s Hospital Medical School, London, UKWe read with great interest the article by Pettit et al1 on the implementation of flipped learning. We wish to offer our perspective as medical students. The study concluded that a combination of lecture-based teaching accompanied with flipped learning activities appealed to most students. We find this response unsurprising. Pettit et al’s1 article documents the reason – the need for a variation in teaching styles for different themes by millennial learners of the modern student community.View the original paper by Pettit and colleagues.  

  6. Involvement of dopamine D1/D5 and D2 receptors in context-dependent extinction learning and memory reinstatement

    Directory of Open Access Journals (Sweden)

    Marion Agnes Emma Andre

    2016-01-01

    Full Text Available Dopamine contributes to the regulation of higher order information processing and executive control. It is important for memory consolidation processes, and for the adaptation of learned responses based on experience. In line with this, under aversive learning conditions, application of dopamine receptor antagonists prior to extinction result in enhanced memory reinstatement. Here, we investigated the contribution of the dopaminergic system to extinction and memory reinstatement (renewal of an appetitive spatial learning task in rodents. Rats were trained for 3 days in a T-maze (context ‘A’ to associate a goal arm with a food reward, despite low reward probability (acquisition phase. On day 4, extinction learning (unrewarded occurred, that was reinforced by a context change (‘B’. On day 5, re-exposure to the (unrewarded ‘A’-context took place (renewal of context ‘A’, followed by extinction of context ‘A’. In control animals, significant extinction occurred on day 4, that was followed by an initial memory reinstatement (renewal on day 5, that was, in turn, succeeded by extinction of renewal. Intracerebral treatment with a D1/D5-receptor antagonist prior to the extinction trials, elicited a potent enhancement of extinction in context ‘B’. By contrast, a D1/D5-agonist impaired renewal in context ’A’. Extinction in the ‘A’ context on day 5 was unaffected by the D1/D5-ligands. Treatment with a D2-receptor antagonist prior to extinction had no overall effect on extinction in context ‘B or renewal in context ‘A’, although extinction of the renewal effect was impaired on day 5, compared to controls.Taken together, these data suggest that dopamine acting on the D1/D5-receptor modulates both acquisition and consolidation of context-dependent extinction. By contrast, the D2-receptor may contribute to context-independent aspects of this kind of extinction learning.

  7. Comparison of Chemistry Learning Outcomes with Inquiry Learning Model and Learning Cycle 5E in Material Solubility and Solubility Multiplication Results

    Directory of Open Access Journals (Sweden)

    Nur Indah Firdausi

    2015-04-01

    Full Text Available Perbandingan Hasil Belajar Kimia dengan Model Pembelajaran Inquiry dan Learning Cycle 5E pada Materi Kelarutan dan Hasil Kali Kelarutan   Abstract: This research is aimed to compare the effectiveness between inquiry and LC 5E in solubility equilibria and the solubility product for students with different prior knowledge. The effectiveness of both learning models is measured from students learning outcome. This quasi experimental research uses factorial2x2 with posttest only design. Research samples are chosen using cluster random sampling. They are two classes of XI IPA SMAN 1 Kepanjen in the 2012/2013 academic year which consist of 31 students in each class. Cognitive learning outcome is measured by test items consist of four objective items and nine subjective items. Technique of data analysis in this research is two way ANOVA. Research results show that: (1 cognitive learning outcome and higher cognitive learning outcome of students in inquiry class is higher than students in LC 5E class; (2 cognitive learning outcome and higher cognitive learning outcome of students who have upper prior knowledge is higher than students who have lower prior knowledge in both inquiry and LC 5E. Key Words: learning outcome, inquiry, learning cycle 5E, solubility equilibria and the solubility product   Abstrak: Penelitian ini bertujuan membandingkan keefektifan model inquiry dan LC 5E pada materi kelarutan dan hasil kali kelarutan untuk siswa dengan kemampuan awal berbeda. Keefektifan model pembelajaran dilihat dari hasil belajar kognitif siswa. Penelitian ini menggunakan rancangan eksperimen semu dengan desain faktorial 2x2. Subjek penelitian dipilih secara cluster random sampling yaitu dua kelas XI IPA SMAN 1 Kepanjen dengan jumlah masing-masing kelas sebanyak 31 siswa. Instrumen perlakuan yang digunakan adalah silabus dan RPP sedangkan instrumen pengukuran berupa soal tes terdiri dari empat soal objektif dan sembilan soal subjektif. Teknik analisis data

  8. CORRELATION OF INTEREST TO LEARN AND USE TIME LEARNING WITH LEARNING ACHIEVEMENT AUTOMOTIVE ELECTRICAL IN CLASS XII LIGHT VEHICLE ENGINEERING SMK PIRI I YOGYAKARTA ACADEMIC YEAR 2013/2014

    Directory of Open Access Journals (Sweden)

    Ari Pujiatmoko

    2014-06-01

    Full Text Available The purpose of this study were: 1 to determine whether there is a correlation between students' interest in learning and the learning achievement of automotive electrical, 2 to determine whether there is a correlation between the use of time studying the learning achievement of automotive electrical, 3 to determine whether there is a correlation between student interest and use the time to learn and the learning achievement of students of class XII automotive electrical TKR SMK PIRI 1 Yogyakarta academic year 2013/2014.  This research was conducted in class XII TKR SMK PIRI 1 Yogyakarta academic year 2013/2014. This study is an ex-post facto. This study used two independent variables and the interest in learning the use of learning time, while the dependent variable is the electrical automotive learning achievement. This study is a population study by the respondent amounted to 100 students. Techniques of data collection using questionnaire techniques and engineering documentation. Research instrument in this study is a questionnaire interest in learning, inquiry learning time management and documentation of student achievement. Trials using the instrument validity and reliability test. The analysis technique used is the prerequisite test for normality, linearity, and multicollinearity. Then test hypotheses using partial correlation analysis techniques and correlation.  The results showed that: 1 students' interest to have a strong positive correlation with school performance automotive electrical ρ value of 0.737; 2 the use of learning time have a low positive correlation with school performance automotive electrical ρ value of 0.275; 3 interest student learning and the use of study time has a very strong positive correlation with learning achievement of students of class XII automotive electrical TKR SMK PIRI I Yogyakarta academic year 2013/2014 as evidenced by the value of R = 0.811.

  9. What did we learn from the Aharonov-Bohm effect? Is spin 1/2 different?

    International Nuclear Information System (INIS)

    Peshkin, M.

    1994-01-01

    I review what has been learned about fundamental issues in quantum mechanics from the Aharonov-Bohm effect. Following that, I consider the Aharonov-Casher effect and the Scalar Aharonov-Bohm effect, in both of which a spin-1/2 particle interacts with a local electromagnetic field through its magnetic moment, and conclude that those effects can be described as observable effects of local torques

  10. Pannexin1 stabilizes synaptic plasticity and is needed for learning.

    Directory of Open Access Journals (Sweden)

    Nora Prochnow

    Full Text Available Pannexin 1 (Panx1 represents a class of vertebrate membrane channels, bearing significant sequence homology with the invertebrate gap junction proteins, the innexins and more distant similarities in the membrane topologies and pharmacological sensitivities with gap junction proteins of the connexin family. In the nervous system, cooperation among pannexin channels, adenosine receptors, and K(ATP channels modulating neuronal excitability via ATP and adenosine has been recognized, but little is known about the significance in vivo. However, the localization of Panx1 at postsynaptic sites in hippocampal neurons and astrocytes in close proximity together with the fundamental role of ATP and adenosine for CNS metabolism and cell signaling underscore the potential relevance of this channel to synaptic plasticity and higher brain functions. Here, we report increased excitability and potently enhanced early and persistent LTP responses in the CA1 region of acute slice preparations from adult Panx1(-/- mice. Adenosine application and N-methyl-D-aspartate receptor (NMDAR-blocking normalized this phenotype, suggesting that absence of Panx1 causes chronic extracellular ATP/adenosine depletion, thus facilitating postsynaptic NMDAR activation. Compensatory transcriptional up-regulation of metabotropic glutamate receptor 4 (grm4 accompanies these adaptive changes. The physiological modification, promoted by loss of Panx1, led to distinct behavioral alterations, enhancing anxiety and impairing object recognition and spatial learning in Panx1(-/- mice. We conclude that ATP release through Panx1 channels plays a critical role in maintaining synaptic strength and plasticity in CA1 neurons of the adult hippocampus. This result provides the rationale for in-depth analysis of Panx1 function and adenosine based therapies in CNS disorders.

  11. Motivated strategies for learning and their association with academic performance of a diverse group of 1styear medical students

    Directory of Open Access Journals (Sweden)

    Shaista Hamid

    2016-05-01

    Full Text Available Background. Most instruments, including the well-known Motivated Strategies for Learning Questionnaire (MSLQ, have been designed in western homogeneous settings. Use of the MSLQ in health professions education is limited. Objective. To assess the MSLQ and its association with the academic performance of a heterogeneous group of 1st-year medical students. Methods. Eighty-three percent of 1st-year medical students consented to participate in this quantitative study. The MSLQ consisted of a motivation strategies component with six subscales, while the learning strategies component had nine subscales. Demographic and academic achievement information of the students was also collected. Stata version 13 (StataCorp LP, USA was used for the statistical analyses of all data. Results. Female students displayed significantly higher motivational scores. Students with prior educational experience and those who attended peer mentoring sessions had significantly higher learning strategy scores. Significant but moderate relationships were found between academic performance and the motivation strategies subsumed within the categories ‘task value’ and ‘self-efficacy for learning performance’. In terms of the ‘learning strategy component’, ‘critical thinking’, and ‘time and study environment’, the composite score was significantly but poorly correlated to academic performance. Conclusion. Overall, limited correlations were found between the MSLQ scores and academic performance. Further investigation of the use of the MSLQ and its association with academic achievement is recommended, with greater focus on specific learning events than on course outcomes. This study highlights the importance of evaluating an instrument in a specific context before accepting the findings of others with regard to the use of the instrument and its correlation with academic performance.

  12. Design of a Networked Learning Master Environment for Professionals

    DEFF Research Database (Denmark)

    Dirckinck-Holmfeld, Lone

    2010-01-01

    The paper is presenting the overall learning design of MIL (Master in ICT and Learning). The learning design is integrating a number of principles: 1. Principles of problem and project based learning 2. Networked learning / learning in communities of practice. The paper will discuss how these pri......The paper is presenting the overall learning design of MIL (Master in ICT and Learning). The learning design is integrating a number of principles: 1. Principles of problem and project based learning 2. Networked learning / learning in communities of practice. The paper will discuss how...

  13. Self-regulated learning processes of medical students during an academic learning task.

    Science.gov (United States)

    Gandomkar, Roghayeh; Mirzazadeh, Azim; Jalili, Mohammad; Yazdani, Kamran; Fata, Ladan; Sandars, John

    2016-10-01

    This study was designed to identify the self-regulated learning (SRL) processes of medical students during a biomedical science learning task and to examine the associations of the SRL processes with previous performance in biomedical science examinations and subsequent performance on a learning task. A sample of 76 Year 1 medical students were recruited based on their performance in biomedical science examinations and stratified into previous high and low performers. Participants were asked to complete a biomedical science learning task. Participants' SRL processes were assessed before (self-efficacy, goal setting and strategic planning), during (metacognitive monitoring) and after (causal attributions and adaptive inferences) their completion of the task using an SRL microanalytic interview. Descriptive statistics were used to analyse the means and frequencies of SRL processes. Univariate and multiple logistic regression analyses were conducted to examine the associations of SRL processes with previous examination performance and the learning task performance. Most participants (from 88.2% to 43.4%) reported task-specific processes for SRL measures. Students who exhibited higher self-efficacy (odds ratio [OR] 1.44, 95% confidence interval [CI] 1.09-1.90) and reported task-specific processes for metacognitive monitoring (OR 6.61, 95% CI 1.68-25.93) and causal attributions (OR 6.75, 95% CI 2.05-22.25) measures were more likely to be high previous performers. Multiple analysis revealed that similar SRL measures were associated with previous performance. The use of task-specific processes for causal attributions (OR 23.00, 95% CI 4.57-115.76) and adaptive inferences (OR 27.00, 95% CI 3.39-214.95) measures were associated with being a high learning task performer. In multiple analysis, only the causal attributions measure was associated with high learning task performance. Self-efficacy, metacognitive monitoring and causal attributions measures were associated

  14. Modelling of Asphalt Concrete Stiffness in the Linear Viscoelastic Region

    Science.gov (United States)

    Mazurek, Grzegorz; Iwański, Marek

    2017-10-01

    Stiffness modulus is a fundamental parameter used in the modelling of the viscoelastic behaviour of bituminous mixtures. On the basis of the master curve in the linear viscoelasticity range, the mechanical properties of asphalt concrete at different loading times and temperatures can be predicted. This paper discusses the construction of master curves under rheological mathematical models i.e. the sigmoidal function model (MEPDG), the fractional model, and Bahia and co-workers’ model in comparison to the results from mechanistic rheological models i.e. the generalized Huet-Sayegh model, the generalized Maxwell model and the Burgers model. For the purposes of this analysis, the reference asphalt concrete mix (denoted as AC16W) intended for the binder coarse layer and for traffic category KR3 (5×105 controlled strain mode. The fixed strain level was set at 25με to guarantee that the stiffness modulus of the asphalt concrete would be tested in a linear viscoelasticity range. The master curve was formed using the time-temperature superposition principle (TTSP). The stiffness modulus of asphalt concrete was determined at temperatures 10°C, 20°C and 40°C and at loading times (frequency) of 0.1, 0.3, 1, 3, 10, 20 Hz. The model parameters were fitted to the rheological models using the original programs based on the nonlinear least squares sum method. All the rheological models under analysis were found to be capable of predicting changes in the stiffness modulus of the reference asphalt concrete to satisfactory accuracy. In the cases of the fractional model and the generalized Maxwell model, their accuracy depends on a number of elements in series. The best fit was registered for Bahia and co-workers model, generalized Maxwell model and fractional model. As for predicting the phase angle parameter, the largest discrepancies between experimental and modelled results were obtained using the fractional model. Except the Burgers model, the model matching quality was

  15. Influences of Formal Learning, Personal Learning Orientation, and Supportive Learning Environment on Informal Learning

    Science.gov (United States)

    Choi, Woojae; Jacobs, Ronald L.

    2011-01-01

    While workplace learning includes formal and informal learning, the relationship between the two has been overlooked, because they have been viewed as separate entities. This study investigated the effects of formal learning, personal learning orientation, and supportive learning environment on informal learning among 203 middle managers in Korean…

  16. African Journal of Biotechnology - Vol 15, No 30 (2016)

    African Journals Online (AJOL)

    Tetranychus urticae Koch.) in peanut · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Maria Isabel G. Martins, Antonio Euzébio G. Sant'Ana, Felipe Matheus T. Vasconcelos, Wbyratan L. Silva, ...

  17. Teacher Collaboration and Student Learning in a Professional Learning Community

    Science.gov (United States)

    Vaughan, Mary Elaine

    2013-01-01

    Researchers have endorsed teacher collaboration within a professional learning community (PLC) that is focused on student learning. Despite these research-based endorsements, several Algebra 1 teachers in a southeastern high school implemented components of a PLC with little or no results in student achievement. The purpose of this study was to…

  18. Circuit mechanisms of sensorimotor learning

    Science.gov (United States)

    Makino, Hiroshi; Hwang, Eun Jung; Hedrick, Nathan G.; Komiyama, Takaki

    2016-01-01

    SUMMARY The relationship between the brain and the environment is flexible, forming the foundation for our ability to learn. Here we review the current state of our understanding of the modifications in the sensorimotor pathway related to sensorimotor learning. We divide the process in three hierarchical levels with distinct goals: 1) sensory perceptual learning, 2) sensorimotor associative learning, and 3) motor skill learning. Perceptual learning optimizes the representations of important sensory stimuli. Associative learning and the initial phase of motor skill learning are ensured by feedback-based mechanisms that permit trial-and-error learning. The later phase of motor skill learning may primarily involve feedback-independent mechanisms operating under the classic Hebbian rule. With these changes under distinct constraints and mechanisms, sensorimotor learning establishes dedicated circuitry for the reproduction of stereotyped neural activity patterns and behavior. PMID:27883902

  19. Educational Modelling Language and Learning Design: new challenges for instructional re-usability and personalized learning

    NARCIS (Netherlands)

    Hummel, Hans; Manderveld, Jocelyn; Tattersall, Colin; Koper, Rob

    2003-01-01

    Published: Hummel, H. G. K., Manderveld, J. M., Tattersall, C.,& Koper, E. J. R. (2004). Educational Modelling Language: new challenges for instructional re-usability and personalized learning. International Journal of Learning Technology, 1, 1, 110-111.

  20. Predicting ionizing radiation exposure using biochemically-inspired genomic machine learning [version 1; referees: 3 approved

    Directory of Open Access Journals (Sweden)

    Jonathan Z.L. Zhao

    2018-02-01

    Full Text Available Background: Gene signatures derived from transcriptomic data using machine learning methods have shown promise for biodosimetry testing. These signatures may not be sufficiently robust for large scale testing, as their performance has not been adequately validated on external, independent datasets. The present study develops human and murine signatures with biochemically-inspired machine learning that are strictly validated using k-fold and traditional approaches. Methods: Gene Expression Omnibus (GEO datasets of exposed human and murine lymphocytes were preprocessed via nearest neighbor imputation and expression of genes implicated in the literature to be responsive to radiation exposure (n=998 were then ranked by Minimum Redundancy Maximum Relevance (mRMR. Optimal signatures were derived by backward, complete, and forward sequential feature selection using Support Vector Machines (SVM, and validated using k-fold or traditional validation on independent datasets. Results: The best human signatures we derived exhibit k-fold validation accuracies of up to 98% (DDB2,  PRKDC, TPP2, PTPRE, and GADD45A when validated over 209 samples and traditional validation accuracies of up to 92% (DDB2,  CD8A,  TALDO1,  PCNA,  EIF4G2,  LCN2,  CDKN1A,  PRKCH,  ENO1,  and PPM1D when validated over 85 samples. Some human signatures are specific enough to differentiate between chemotherapy and radiotherapy. Certain multi-class murine signatures have sufficient granularity in dose estimation to inform eligibility for cytokine therapy (assuming these signatures could be translated to humans. We compiled a list of the most frequently appearing genes in the top 20 human and mouse signatures. More frequently appearing genes among an ensemble of signatures may indicate greater impact of these genes on the performance of individual signatures. Several genes in the signatures we derived are present in previously proposed signatures. Conclusions: Gene signatures

  1. Quantum learning algorithms for quantum measurements

    Energy Technology Data Exchange (ETDEWEB)

    Bisio, Alessandro, E-mail: alessandro.bisio@unipv.it [QUIT Group, Dipartimento di Fisica ' A. Volta' and INFN, via Bassi 6, 27100 Pavia (Italy); D' Ariano, Giacomo Mauro, E-mail: dariano@unipv.it [QUIT Group, Dipartimento di Fisica ' A. Volta' and INFN, via Bassi 6, 27100 Pavia (Italy); Perinotti, Paolo, E-mail: paolo.perinotti@unipv.it [QUIT Group, Dipartimento di Fisica ' A. Volta' and INFN, via Bassi 6, 27100 Pavia (Italy); Sedlak, Michal, E-mail: michal.sedlak@unipv.it [QUIT Group, Dipartimento di Fisica ' A. Volta' and INFN, via Bassi 6, 27100 Pavia (Italy); Institute of Physics, Slovak Academy of Sciences, Dubravska cesta 9, 845 11 Bratislava (Slovakia)

    2011-09-12

    We study quantum learning algorithms for quantum measurements. The optimal learning algorithm is derived for arbitrary von Neumann measurements in the case of training with one or two examples. The analysis of the case of three examples reveals that, differently from the learning of unitary gates, the optimal algorithm for learning of quantum measurements cannot be parallelized, and requires quantum memories for the storage of information. -- Highlights: → Optimal learning algorithm for von Neumann measurements. → From 2 copies to 1 copy: the optimal strategy is parallel. → From 3 copies to 1 copy: the optimal strategy must be non-parallel.

  2. Quantum learning algorithms for quantum measurements

    International Nuclear Information System (INIS)

    Bisio, Alessandro; D'Ariano, Giacomo Mauro; Perinotti, Paolo; Sedlak, Michal

    2011-01-01

    We study quantum learning algorithms for quantum measurements. The optimal learning algorithm is derived for arbitrary von Neumann measurements in the case of training with one or two examples. The analysis of the case of three examples reveals that, differently from the learning of unitary gates, the optimal algorithm for learning of quantum measurements cannot be parallelized, and requires quantum memories for the storage of information. -- Highlights: → Optimal learning algorithm for von Neumann measurements. → From 2 copies to 1 copy: the optimal strategy is parallel. → From 3 copies to 1 copy: the optimal strategy must be non-parallel.

  3. Influence Model Assisted Learning Cycle Mind Map to Achievement Physics Laboratory Judging from the performance Grade VIII SMPN 1 Rejoso Pasuruan

    OpenAIRE

    Ary Analisa Rahma

    2014-01-01

    Pengaruh Model Siklus Belajar Berbantuan Mind Map terhadap Prestasi Belajar Fisika Ditinjau dari Kinerja Laboratorium Siswa Kelas VIII SMPN 1 Rejoso Kabupaten Pasuruan Abstract: This study aimed to examine the effect of the learning cycle models aided the mind map on the learning achievement in terms of the performance of laboratory physics class VIII student on light material in SMP Negeri 1 Rejoso Pasuruan. This study is a quasi-experimental research. The research design used is a 2 x 2...

  4. Comparative Study on Theoretical and Machine Learning Methods for Acquiring Compressed Liquid Densities of 1,1,1,2,3,3,3-Heptafluoropropane (R227ea via Song and Mason Equation, Support Vector Machine, and Artificial Neural Networks

    Directory of Open Access Journals (Sweden)

    Hao Li

    2016-01-01

    Full Text Available 1,1,1,2,3,3,3-Heptafluoropropane (R227ea is a good refrigerant that reduces greenhouse effects and ozone depletion. In practical applications, we usually have to know the compressed liquid densities at different temperatures and pressures. However, the measurement requires a series of complex apparatus and operations, wasting too much manpower and resources. To solve these problems, here, Song and Mason equation, support vector machine (SVM, and artificial neural networks (ANNs were used to develop theoretical and machine learning models, respectively, in order to predict the compressed liquid densities of R227ea with only the inputs of temperatures and pressures. Results show that compared with the Song and Mason equation, appropriate machine learning models trained with precise experimental samples have better predicted results, with lower root mean square errors (RMSEs (e.g., the RMSE of the SVM trained with data provided by Fedele et al. [1] is 0.11, while the RMSE of the Song and Mason equation is 196.26. Compared to advanced conventional measurements, knowledge-based machine learning models are proved to be more time-saving and user-friendly.

  5. Classification of Cytochrome P450 1A2 Inhibitors and Non-Inhibitors by Machine Learning Techniques

    DEFF Research Database (Denmark)

    Vasanthanathan, Poongavanam; Taboureau, Olivier; Oostenbrink, Chris

    2009-01-01

    of CYP1A2 inhibitors and non-inhibitors. Training and test sets consisted of about 400 and 7000 compounds, respectively. Various machine learning techniques, like binary QSAR, support vector machine (SVM), random forest, kappa nearest neighbors (kNN), and decision tree methods were used to develop...

  6. Blended Learning Based on Schoology: Effort of Improvement Learning Outcome and Practicum Chance in Vocational High School

    Science.gov (United States)

    Irawan, Vincentius Tjandra; Sutadji, Eddy; Widiyanti

    2017-01-01

    The aims of this study were to determine: (1) the differences in learning outcome between Blended Learning based on Schoology and Problem-Based Learning, (2) the differences in learning outcome between students with prior knowledge of high, medium, and low, and (3) the interaction between Blended Learning based on Schoology and prior knowledge to…

  7. Learning, Tablet, Culture-Coherence?

    Science.gov (United States)

    Norqvist, Lars

    2016-01-01

    This paper presents understandings of learning in schools where Internet-enabled Information and Communication Technologies (ICTs) are taken for granted. The context is a full-scale 1:1 tablet project in Danish municipality schools where this study bring forward expressions of learning from one class (12-13 year old children) in order to offer…

  8. Perspectives on Advanced Learning Technologies and Learning Networks and Future Aerospace Workforce Environments

    Science.gov (United States)

    Noor, Ahmed K. (Compiler)

    2003-01-01

    An overview of the advanced learning technologies is given in this presentation along with a brief description of their impact on future aerospace workforce development. The presentation is divided into five parts (see Figure 1). In the first part, a brief historical account of the evolution of learning technologies is given. The second part describes the current learning activities. The third part describes some of the future aerospace systems, as examples of high-tech engineering systems, and lists their enabling technologies. The fourth part focuses on future aerospace research, learning and design environments. The fifth part lists the objectives of the workshop and some of the sources of information on learning technologies and learning networks.

  9. Taastatud Jaani kiriku interjöörid 21. sajandi kontekstis / Krista Kodres

    Index Scriptorium Estoniae

    Kodres, Krista, 1957-

    2006-01-01

    Tartu Jaani kiriku interjööridest. Kunstiajaloolane Kaur Alttoa. Sisekujundajad: Tea Tammelaan, Malle Jürgenson, Krista Lepland. Terrakotaskulptuure on konserveerinud, algul koos sakslastega (Sven Wallasch, keemik Eberhard Wendler), Eve Alttoa. Fassaadiskulptuuride koopiad valmistab Isabel Aaso. Ka Urmo Rausi akendeprojektist

  10. La conservación del patrimonio genético : colecciones de ADN y tejidos

    OpenAIRE

    Rey Fraile, Isabel

    2014-01-01

    Memoria preparada para optar al grado de doctor presentada por Isabel Rey Fraile en la Universidad Complutense de Madrid, Facultad de Ciencias biológicas, Dpto de Biología celular. Fecha de la defensa de tesis el 30 junio 2014

  11. Modulation of sphingosine 1-phosphate (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism.

    Science.gov (United States)

    Wu, Hongmei; Zhang, Quanzhi; Gao, Jingquan; Sun, Caihong; Wang, Jia; Xia, Wei; Cao, Yonggang; Hao, Yanqiu; Wu, Lijie

    2018-03-01

    Autism spectrum disorders (ASD) are a set of pervasive neurodevelopmental disorders that manifest in early childhood, and it is growing up to be a major cause of disability in children. However, the etiology and treatment of ASD are not well understood. In our previous study, we found that serum levels of sphingosine 1-phosphate (S1P) were increased significantly in children with autism, indicating that S1P levels may be involved in ASD. The objective of this study was to identify a link between increased levels of S1P and neurobehavioral changes in autism. We utilized a valproic acid (VPA) -induced rat model of autism to evaluate the levels of S1P and the expression of sphingosine kinase (SphK), a key enzyme for S1P production, in serum and hippocampal tissue. Furthermore, we assessed cognitive functional changes and histopathological and neurochemical alterations in VPA-exposed rats after SphK blockade to explore the possible link between increased levels of S1P and neurobehavioral changes in autism. We found that SphK2 and S1P are upregulated in hippocampal tissue from VPA-exposed rats, while pharmacological inhibition of SphK reduced S1P levels, attenuated spatial learning and memory impairments, increased the expression of phosphorylated CaMKII and CREB and autophagy-related proteins, inhibited cytochrome c release, decreased the expression of apoptosis related proteins, and protected against neuronal loss in the hippocampus. We have demonstrated that an increased level of SphK2/S1P is involved in the spatial learning and memory impairments of autism, and this signaling pathway represents a novel therapeutic target and direction for future studies.

  12. β-asarone improves learning and memory and reduces Acetyl Cholinesterase and Beta-amyloid 42 levels in APP/PS1 transgenic mice by regulating Beclin-1-dependent autophagy.

    Science.gov (United States)

    Deng, Minzhen; Huang, Liping; Ning, Baile; Wang, Nanbu; Zhang, Qinxin; Zhu, Caixia; Fang, Yongqi

    2016-12-01

    Alzheimer's disease (AD) is the most common neurodegenerative disorder in the elderly, and studies have suggested that β-asarone has pharmacological effects on beta-amyloid (Aβ) injected in the rat hippocampus. However, the effect of β-asarone on autophagy in the APP/PS1 transgenic mouse is unreported. APP/PS1 transgenic mice were randomly divided into six groups (n=10/group): an untreated group, an Aricept-treated group, a 3-MA-treated group, a rapamycin-treated group, an LY294002-treated group, a β-asarone-treated group. The control group consisted of wild-type C57BL/6 mice. All treatments were administered to the mice for 30 days. Spatial learning and memory were assessed by water maze, passive avoidance, and step-down tests. AChE and Aβ 42 levels in the hippocampus were determined by ELISA. p-Akt, p-mTOR, and LC3B expression were detected by flow cytometry. The expression of p-Akt, p-mTOR, Beclin-1, and p62 proteins was assessed by western blot. Changes in autophagy were viewed using a transmission electron microscope. APP and Beclin-1 mRNA levels were measured by Real-Time PCR. The learning and memory of APP/PS1 transgenic mice were improved significantly after β-asarone treatment compared with the untreated group. In addition, β-asarone treatment reduced AChE and Aβ 42 levels, increased p-mTOR and p62 expression, decreased p-Akt, Beclin-1, and LC3B expression, decreased the number of autophagosomes and reduced APP mRNA and Beclin-1 mRNA levels compared with the untreated group. That is, β-asarone treatment can improve the learning and memory abilities of APP/PS1 transgenic mouse by inhibiting Beclin-1-dependent autophagy via the PI3K/Akt/mTOR pathway. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Effects of the glucagon-like polypeptide-1 analogue (Val8)GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain.

    Science.gov (United States)

    McGovern, Stephen F J; Hunter, Kerry; Hölscher, Christian

    2012-09-14

    Type 2 diabetes (T2DM) has been identified as a risk factor for Alzheimer's disease. Here, we tested the properties of the glucagon-like polypetide-1 (GLP-1) analogue (Val8)GLP-1, a drug originally developed as a treatment for T2DM at a range of doses (2.5 nmol; 25 nmol; 100 nmol; or 250 nmol/kg bw ip.) in an acute memory study in wild type C57B/l6 mice. We also tested (Val8)GLP-1 and the GLP-1 receptor antagonist exendin (9-39) in a chronic study (3 weeks at 25 nmol/kg bw ip. once-daily). We found that (Val8)GLP-1 crossed the blood brain barrier readily and that peripheral injection increased levels in the brain 30 min post-injection ip. but not 2h post-injection in rats. In the acute study, the low dose of 2.5 nmol/kg ip. enhanced motor activity in the open field task, while total distance travelled, exploratory behaviour and anxiety was not affected at any dose. Learning an object recognition task was not affected either. In the chronic study, no effect was observed in the open field assessment. The antagonist exendin (9-39) impaired object recognition learning and spatial learning in a water maze task, demonstrating the importance of GLP-1 signalling in memory formation. Locomotor activity was also affected in some cases. Blood sugar levels and insulin sensitivity was not affected in chronically treated mice. Neuronal stem cells and neurogenesis was enhanced by (Val8)GLP-1 in the dentate gyrus of wild type mice. The results demonstrate that (Val8)GLP-1 is safe in a range of doses, crosses the BBB and has potentially beneficial effects in the CNS by enhancing neurogenesis. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. E-learning for health professionals.

    Science.gov (United States)

    Vaona, Alberto; Banzi, Rita; Kwag, Koren H; Rigon, Giulio; Cereda, Danilo; Pecoraro, Valentina; Tramacere, Irene; Moja, Lorenzo

    2018-01-21

    /dL (adjusted difference 4.0%, 95% confidence interval (CI) -0.3 to 7.9, N = 6399 patients, 1 study) and the proportion with glycated haemoglobin level of less than 8% (adjusted difference 4.6%, 95% CI -1.5 to 9.8, 3114 patients, 1 study). At 3- to 12-month follow-up, low-certainty evidence indicates that e-learning may make little or no difference on the following behaviours in health professionals: screening for dyslipidaemia (OR 0.90, 95% CI 0.77 to 1.06, 6027 patients, 2 studies) and treatment for dyslipidaemia (OR 1.15, 95% CI 0.89 to 1.48, 5491 patients, 2 studies). It is uncertain whether e-learning improves or reduces health professionals' skills (2912 health professionals; 6 studies; very low-certainty evidence), and it may make little or no difference in health professionals' knowledge (3236 participants; 11 studies; low-certainty evidence).Due to the paucity of studies and data, we were unable to explore differences in effects across different subgroups. Owing to poor reporting, we were unable to collect sufficient information to complete a meaningful 'Risk of bias' assessment for most of the quality criteria. We evaluated the risk of bias as unclear for most studies, but we classified the largest trial as being at low risk of bias. Missing data represented a potential source of bias in several studies. When compared to traditional learning, e-learning may make little or no difference in patient outcomes or health professionals' behaviours, skills or knowledge. Even if e-learning could be more successful than traditional learning in particular medical education settings, general claims of it as inherently more effective than traditional learning may be misleading.

  15. Academic Achievement from Using the Learning Medium Via a Tablet Device Based on Multiple Intelligences in Grade 1 Elementary Student.

    Science.gov (United States)

    Nuallaong, Winitra; Nuallaong, Thanya; Preechadirek, Nongluck

    2015-04-01

    To measure academic achievement of the multiple intelligence-based learning medium via a tablet device. This is a quasi-experimental research study (non-randomized control group pretest-posttest design) in 62 grade 1 elementary students (33 males and 29 females). Thirty-one students were included in an experimental group using purposive sampling by choosing a student who had highest multiple intelligence test scores in logical-mathematic. Then, this group learned by the new learning medium via a tablet which the application matched to logical-mathematic multiple intelligence. Another 31 students were included in a control group using simple random sampling and then learning by recitation. Both groups did pre-test and post-test vocabulary. Thirty students in the experimental group and 24 students in the control group increased post-test scores (odds ratio = 8.75). Both groups made significant increasing in post-test scores. The experimental group increased 9.07 marks (95% CI 8.20-9.93) significantly higher than the control group which increased 4.39 marks (95% CI 3.06-5.72) (t = -6.032, df = 51.481, p learning from either multiple intelligence-based learning medium via a tablet or recitation can contribute academic achievement, learningfrom the new medium contributed more achievement than recitation. The new learning medium group had higher post-test scores 8.75 times than the recitation group. Therefore, the new learning medium is more effective than the traditional recitation in terms of academic achievement. This study has limitations because samples came from the same school. However, the previous study in Thailand did notfind a logical-mathematical multiple intelligence difference among schools. In the future, long-term research to find how the new learning medium affects knowledge retention will support the advantage for life-long learning.

  16. Learning to make things happen: Infants' observational learning of social and physical causal events.

    Science.gov (United States)

    Waismeyer, Anna; Meltzoff, Andrew N

    2017-10-01

    Infants learn about cause and effect through hands-on experience; however, they also can learn about causality simply from observation. Such observational causal learning is a central mechanism by which infants learn from and about other people. Across three experiments, we tested infants' observational causal learning of both social and physical causal events. Experiment 1 assessed infants' learning of a physical event in the absence of visible spatial contact between the causes and effects. Experiment 2 developed a novel paradigm to assess whether infants could learn about a social causal event from third-party observation of a social interaction between two people. Experiment 3 compared learning of physical and social events when the outcomes occurred probabilistically (happening some, but not all, of the time). Infants demonstrated significant learning in all three experiments, although learning about probabilistic cause-effect relations was most difficult. These findings about infant observational causal learning have implications for children's rapid nonverbal learning about people, things, and their causal relations. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Using computer-assisted learning to engage diverse learning styles in understanding business management principles.

    Science.gov (United States)

    Frost, Mary E; Derby, Dustin C; Haan, Andrea G

    2013-01-01

    Objective : Changes in small business and insurance present challenges for newly graduated chiropractors. Technology that reaches identified, diverse learning styles may assist the chiropractic student in business classes to meet course outcomes better. Thus, the purpose of our study is to determine if the use of technology-based instructional aids enhance students' mastery of course learning outcomes. Methods : Using convenience sampling, 86 students completed a survey assessing course learning outcomes, learning style, and the helpfulness of lecture and computer-assisted learning related to content mastery. Quantitative analyses occurred. Results : Although respondents reported not finding the computer-assisted learning as helpful as the lecture, significant relationships were found between pre- and post-assisted learning measures of the learning outcomes 1 and 2 for the visual and kinesthetic groups. Surprisingly, however, all learning style groups exhibited significant pre- and post-assisted learning appraisal relationships with learning outcomes 3 and 4. Conclusion : While evidence exists within the current study of a relationship between students' learning of the course content corollary to the use of technologic instructional aids, the exact nature of the relationship remains unclear.

  18. Chapter Five: Language Learning and Discursive Practice

    Science.gov (United States)

    Young, Richard F.

    2008-01-01

    This chapter is framed by the three questions related to learning in Practice Theory posed by Johannes Wagner (2008): (1) What is learned?; (2) Who is learning?; and (3) Who is participating in the learning? These questions are addressed in two learning theories: Language Socialization and Situated Learning theory. In Language Socialization, the…

  19. Perceptual Learning Style and Learning Proficiency: A Test of the Hypothesis

    Science.gov (United States)

    Kratzig, Gregory P.; Arbuthnott, Katherine D.

    2006-01-01

    Given the potential importance of using modality preference with instruction, the authors tested whether learning style preference correlated with memory performance in each of 3 sensory modalities: visual, auditory, and kinesthetic. In Study 1, participants completed objective measures of pictorial, auditory, and tactile learning and learning…

  20. Classroom Habit(us): Digital Learning Tools in a Blended Learning Program

    DEFF Research Database (Denmark)

    Borsotti, Valeria; Møllenbach, Emilie

    2016-01-01

    In this exploratory case study we map the educational practice of teachers and students in a professional master of Interaction Design. Through a grounded analysis of the context we describe and reflect on: 1) the use of digital learning tools in a blended learning environment, 2) co...

  1. Comparison the Application of PBL (Project Based Learning and PBL (Problem Based Learning Learning Model on Online Marketing Subjects

    Directory of Open Access Journals (Sweden)

    Agnes Dini Mardani

    2017-09-01

    Full Text Available Purpose of this study are (1 the application of learning PjBL with PBL to improve study results students, (2 assessing the domain affective, cognitive, and psychomotor, (3 the difference study results use the PjBL with PBL to improve study results students. The research is research quantitative and including research apparent experiment (quasi eksperiment by taking sample class two classes X PM 1 as a class experiment and class X PM 2 as a class control. Research instruments used for data collection namely: (1 tests to pretes and postest used to determine the cognitive assessment, (2 sheets observation affective, (3 sheets of the process for the psychomotor. The trial research instruments use the validity and reabilitas. Analysis techniques data using: (1 test a prerequisite analysis consisting of normality test and the homogeneity (2 T test unpaired which ended with the help of computer programs spss. Based on the result of this research can be concluded that: (1 the application of PjBL (Project Based Learning and PBL (Problem Based Learning should be conducted well in accordance syntax learning, (2 assessing the cognitive students have a difference and class experiment having an average higher than class control, (3 assessing the results affective students have a difference and on the application of PjBL is better than PBL.

  2. Motivate to Learn: other ways of learning Biology, Maths and other Sciences

    OpenAIRE

    Almeida, M. J.; Nobre, Alexandra; Pinto, Augusta; Cunha, Lília; Maciel, Elsa Marina Costa; Almeida Aguiar, Cristina; Forjaz, Maria Antónia

    2014-01-01

    The development of teaching and learning strategies that effectively assist in the understanding of scientific knowledge is an ongoing challenge. Doing experiments outside the classroom, one of the recommended approaches, presents some risks, because students can divert their attention from the pedagogical objective of activity [1]. However, experts agree in considering that learning outside the classroom can be used to facilitate Education. Providing students with learning activities in rele...

  3. Operation of TRR-1/M1 for 25 years and lessons learned in management of safety and safety culture

    International Nuclear Information System (INIS)

    Keinmeesuke, Sirichai

    2002-01-01

    The first Thai Research Reactor, TRR-1, was installed and put into operation in 1962. In 1975 the reactor was converted to a 2 MW TRIGA Mark III by replacing of the reactor core and the control system. The renamed TRR-1/M1 research reactor went critical again in November 1977. TRR-1/M1 has been operated safely for 25 years with its main utilization in research, isotope production and training. Safety management and safety culture have been implemented for 25 years both in the legislation level and the operation level. There was no nuclear incident and there were a few radiological incidents during the 25 years of operation of TRR-1/M1. The lessons learned from the incident events such as the release of N-16 and Ar-41, the release of radioactive Bromine gave valued opportunities to improve our operation procedure, safety procedure and safety culture. All type of activities with respect to safety culture such as individual awareness, commitment, motivation, supervision and responsibility have been seriously reviewed and being set as normal practices. (author)

  4. To have or to learn? The effects of materialism on British and Chinese children's learning.

    Science.gov (United States)

    Ku, Lisbeth; Dittmar, Helga; Banerjee, Robin

    2014-05-01

    This article presents a systematic attempt to examine the associations of materialism with learning in 9- to 11-year-old children in 2 countries of similar economic development but different cultural heritage. Using cross-sectional, longitudinal, and experimental methods, we test a theoretically driven model of associations among materialism, learning motivations, and learning outcomes. Convergent findings suggest that a materialist orientation in elementary school children lowers intrinsic learning motivations, fosters extrinsic learning motivations, and leads to poorer learning outcomes. Materialism was linked directly to lower exam performance, and this link was mediated by lower mastery and heightened performance goals, with patterns not differing between British and Hong Kong Chinese children (Study 1). A follow-up showed that initial materialism predicted worse exam grades 1 year later, suggesting a detrimental long-term effect on Chinese children's school performance (Study 2). We then tested relationships between materialism and learning experimentally, by priming a momentary (state) orientation toward materialism. Writing about material possessions and money affected Chinese children's learning motivations, so that they endorsed lower mastery and higher performance goals (Study 3). A video-diary materialism prime had significant effects on actual learning behaviors, leading British children to (a) choose a performance-oriented learning task over a mastery-oriented task and (b) give up on the task more quickly (Study 4). This research has important implications for personality psychology, educational policy, and future research.

  5. An Annotated Bibliography of Accelerated Learning

    Science.gov (United States)

    Garcia, GNA

    2007-01-01

    A rich narrative-style bibliography of accelerated learning (reviewing six articles published between 1995-2003). Articles reviewed include: (1) Accelerative learning and the Emerging Science of Wholeness (D. D. Beale); (2) Effective Teaching in Accelerated Learning Programs (D. Boyd); (3) A Critical Theory Perspective on Accelerated Learning (S.…

  6. The Impact of Individual Learning Accounts: A Study of the Early and Potential Impact of Individual Learning Accounts on Learning Providers and Learning. Research Report.

    Science.gov (United States)

    Gray, Michael; Peters, Jane; Fletcher, Mick; Kirk, Gordon

    The impact of individual learning accounts (ILAs) on the success of learners in post-16 education sector in the United Kingdom was explored through an examination of available research on ILAs. The following were among the study's 12 messages for providers, the Department for Education and Skills, and the Individual Learning Account Centre: (1)…

  7. Health education and multimedia learning: educational psychology and health behavior theory (Part 1).

    Science.gov (United States)

    Mas, Francisco G Soto; Plass, Jan; Kane, William M; Papenfuss, Richard L

    2003-07-01

    When health education researchers began to investigate how individuals make decisions related to health and the factors that influence health behaviors, they referred to frameworks shared by educational and learning research. Health education adopted the basic principles of the cognitive revolution, which were instrumental in advancing the field. There is currently a new challenge to confront: the widespread use of new technologies for health education. To better overcome this challenge, educational psychology and instructional technology theory should be considered. Unfortunately, the passion to incorporate new technologies too often overshadows how people learn or, in particular, how people learn through computer technologies. This two-part article explains how educational theory contributed to the early development of health behavior theory, describes the most relevant multimedia learning theories and constructs, and provides recommendations for developing multimedia health education programs and connecting theory and practice.

  8. Learning SPARQL

    CERN Document Server

    DuCharme, Bob

    2011-01-01

    Get hands-on experience with SPARQL, the RDF query language that's become a key component of the semantic web. With this concise book, you will learn how to use the latest version of this W3C standard to retrieve and manipulate the increasing amount of public and private data available via SPARQL endpoints. Several open source and commercial tools already support SPARQL, and this introduction gets you started right away. Begin with how to write and run simple SPARQL 1.1 queries, then dive into the language's powerful features and capabilities for manipulating the data you retrieve. Learn wha

  9. What is Social Learning?

    Directory of Open Access Journals (Sweden)

    Mark S. Reed

    2010-12-01

    between individual and wider social learning. Many unsubstantiated claims for social learning exist, and there is frequently confusion between the concept itself and its potential outcomes. This lack of conceptual clarity has limited our capacity to assess whether social learning has occurred, and if so, what kind of learning has taken place, to what extent, between whom, when, and how. This response attempts to provide greater clarity on the conceptual basis for social learning. We argue that to be considered social learning, a process must: (1 demonstrate that a change in understanding has taken place in the individuals involved; (2 demonstrate that this change goes beyond the individual and becomes situated within wider social units or communities of practice; and (3 occur through social interactions and processes between actors within a social network. A clearer picture of what we mean by social learning could enhance our ability to critically evaluate outcomes and better understand the processes through which social learning occurs. In this way, it may be possible to better facilitate the desired outcomes of social learning processes.

  10. Learning from Number Board Games: You Learn What You Encode

    Science.gov (United States)

    Laski, Elida V.; Siegler, Robert S.

    2014-01-01

    We tested the hypothesis that encoding the numerical-spatial relations in a number board game is a key process in promoting learning from playing such games. Experiment 1 used a microgenetic design to examine the effects on learning of the type of counting procedure that children use. As predicted, having kindergartners count-on from their current…

  11. Teachers' Spatial Anxiety Relates to 1st-and 2nd-Graders' Spatial Learning

    Science.gov (United States)

    Gunderson, Elizabeth A.; Ramirez, Gerardo; Beilock, Sian L.; Levine, Susan C.

    2013-01-01

    Teachers' anxiety about an academic domain, such as math, can impact students' learning in that domain. We asked whether this relation held in the domain of spatial skill, given the importance of spatial skill for success in math and science and its malleability at a young age. We measured 1st-and 2nd-grade teachers' spatial anxiety…

  12. The Influence of Interactive Learning Materials on Self-Regulated Learning and Learning Satisfaction of Primary School Teachers in Mongolia

    Directory of Open Access Journals (Sweden)

    Shengru Li

    2018-04-01

    Full Text Available The purpose of this study was to investigate the effects of interactive learning materials on learners’ self-regulated learning processes and learning satisfaction. A two-group experimental design was employed for 285 primary school teachers involved in teacher training. Teachers in the experimental group utilised interactive learning materials along with training videos and guidelines for their self-development at the school level. Teachers in the control group conducted self-development only with training videos and guidelines. The result was analysed using self-regulated learning theory explaining how one’s self-regulation processes affect learning satisfaction. Five self-regulation processes were identified in this study: internal motivation, motivation for better assessment, planning and organizing skills, critical and positive thinking skills, and effort regulation. The analysis was conducted in two steps. First, t-test analysis was used to identify the significant differences between the experimental group and the control group. The analysis revealed: (1 teachers conducting self-development with interactive learning materials were highly motivated to achieve better teacher assessment, (2 teachers with interactive learning materials had higher learning satisfaction. Second, the study further investigated the effect of interactive materials on the relationship between self-regulation processes and learning satisfaction, using moderation analysis. The results showed that interactive materials significantly affect the relationship between motivation for better assessment and learning satisfaction, as well as the relationship between internal motivation and learning satisfaction. These results were complemented by qualitative analysis including interviews and focus group discussions with teachers.

  13. Learning Mathematics through Programming

    DEFF Research Database (Denmark)

    Misfeldt, Morten; Ejsing-Duun, Stine

    2015-01-01

    In this paper we explore the potentials for learning mathematics through programming by a combination of theoretically derived potentials and cases of practical pedagogical work. We propose a model with three interdependent learning potentials as programming which can: (1) help reframe the students...... to mathematics is paramount. Analyzing two cases, we suggest a number of ways in which didactical attention to epistemic mediation can support learning mathematics....

  14. The difference in learning culture and learning performance between a traditional clinical placement, a dedicated education unit and work-based learning.

    Science.gov (United States)

    Claeys, Maureen; Deplaecie, Monique; Vanderplancke, Tine; Delbaere, Ilse; Myny, Dries; Beeckman, Dimitri; Verhaeghe, Sofie

    2015-09-01

    An experiment was carried out on the bachelor's degree course in nursing with two new clinical placement concepts: workplace learning and the dedicated education centre. The aim was to establish a learning culture that creates a sufficiently high learning performance for students. The objectives of this study are threefold: (1) to look for a difference in the "learning culture" and "learning performance" in traditional clinical placement departments and the new clinical placement concepts, the "dedicated education centre" and "workplace learning"; (2) to assess factors influencing the learning culture and learning performance; and (3) to investigate whether there is a link between the learning culture and the learning performance. A non-randomised control study was carried out. The experimental group consisted of 33 final-year nursing undergraduates who were following clinical placements at dedicated education centres and 70 nursing undergraduates who undertook workplace learning. The control group consisted of 106 students who followed a traditional clinical placement. The "learning culture" outcome was measured using the Clinical Learning Environment, Supervision and Nurse Teacher scale. The "learning performance" outcome consisting of three competencies was measured using the Nursing Competence Questionnaire. The traditional clinical placement concept achieved the highest score for learning culture (plearning performance of which the dedicated education centres achieved the highest scores. The 3 clinical placement concepts showed marked differences in learning performance for the "assessment" competency (plearning can be seen as complementary clinical placement concepts. The organisation of clinical placements under the dedicated education centre concept and workplace learning is recommended for final-year undergraduate nursing students. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Supporting Student Learning in Computer Science Education via the Adaptive Learning Environment ALMA

    Directory of Open Access Journals (Sweden)

    Alexandra Gasparinatou

    2015-10-01

    Full Text Available This study presents the ALMA environment (Adaptive Learning Models from texts and Activities. ALMA supports the processes of learning and assessment via: (1 texts differing in local and global cohesion for students with low, medium, and high background knowledge; (2 activities corresponding to different levels of comprehension which prompt the student to practically implement different text-reading strategies, with the recommended activity sequence adapted to the student’s learning style; (3 an overall framework for informing, guiding, and supporting students in performing the activities; and; (4 individualized support and guidance according to student specific characteristics. ALMA also, supports students in distance learning or in blended learning in which students are submitted to face-to-face learning supported by computer technology. The adaptive techniques provided via ALMA are: (a adaptive presentation and (b adaptive navigation. Digital learning material, in accordance with the text comprehension model described by Kintsch, was introduced into the ALMA environment. This material can be exploited in either distance or blended learning.

  16. Generation Z, Meet Cooperative Learning

    Science.gov (United States)

    Igel, Charles; Urquhart, Vicki

    2012-01-01

    Today's Generation Z teens need to develop teamwork and social learning skills to be successful in the 21st century workplace. Teachers can help students develop these skills and enhance academic achievement by implementing cooperative learning strategies. Three key principles for successful cooperative learning are discussed. (Contains 1 figure.)

  17. Benchmark calculations on residue production within the EURISOL DS project. Part 1: thin targets

    Energy Technology Data Exchange (ETDEWEB)

    David, J.C.; Blideanu, V.; Boudard, A.; Dore, D.; Leray, S.; Rapp, B.; Ridikas, D.; Thiolliere, N

    2006-12-15

    We have begun this benchmark study using mass distribution data of reaction products obtained at GSI in inverse kinematics. This step has allowed us to make a first selection among 10 spallation models; in this way the first assessment of the quality of the models was obtained. Then, in a second part, experimental mass distributions for some elements, which either are interesting as radioactive ion beams or important due to the safety and radioprotection issues (alpha or gamma emitters), will be also compared to model calculations. These data have been obtained for an equivalent 0.8 or 1.0 GeV proton beam, which is approximately the proposed projectile energy. We note that in realistic thick targets the proton beam will be slowed down and some secondary particles will be produced. Therefore, the residual nuclei production at lower energies is also important. For this reason, we also performed in the third part of this work some excitation function calculations and the associated data obtained with gamma-spectroscopy to test the models in a wide projectile energy range. We conclude that INCL4/Abla and Isabel/Abla are the best model combinations which we recommend. We also note that the agreement between model and data are better with 1 GeV protons than with 100-200 MeV protons.

  18. Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model.

    Science.gov (United States)

    Lim, Chae-Seok; Hoang, Elizabeth T; Viar, Kenneth E; Stornetta, Ruth L; Scott, Michael M; Zhu, J Julius

    2014-02-01

    Fragile X syndrome, caused by the loss of Fmr1 gene function, is the most common form of inherited mental retardation, with no effective treatment. Using a tractable animal model, we investigated mechanisms of action of a few FDA-approved psychoactive drugs that modestly benefit the cognitive performance in fragile X patients. Here we report that compounds activating serotonin (5HT) subtype 2B receptors (5HT2B-Rs) or dopamine (DA) subtype 1-like receptors (D1-Rs) and/or those inhibiting 5HT2A-Rs or D2-Rs moderately enhance Ras-PI3K/PKB signaling input, GluA1-dependent synaptic plasticity, and learning in Fmr1 knockout mice. Unexpectedly, combinations of these 5HT and DA compounds at low doses synergistically stimulate Ras-PI3K/PKB signal transduction and GluA1-dependent synaptic plasticity and remarkably restore normal learning in Fmr1 knockout mice without causing anxiety-related side effects. These findings suggest that properly dosed and combined FDA-approved psychoactive drugs may effectively treat the cognitive impairment associated with fragile X syndrome.

  19. Teaching and Learning Astronomy

    Science.gov (United States)

    Pasachoff, Jay; Percy, John

    2009-07-01

    Preface; Part I. Astronomy in the Curriculum Around the World: Preface; 1. Why astronomy is useful and should be included in the school curriculum John R. Percy; 2. Astronomy and mathematics education Rosa M. Ros; 3. Astronomy in the curriculum around the world; 4. Engaging gifted science students through astronomy Robert Hollow; 5. Poster highlights: astronomy in the curriculum around the world; Part II. Astronomy Education Research: Preface; 6. Astronomy education research down under John M. Broadfoot and Ian S. Ginns; 7. A contemporary review of K-16 astronomy education research Janelle M. Bailey and Timothy F. Slater; 8. Implementing astronomy education research Leonarda Fucili; 9. The Astronomy Education Review: report on a new journal Sidney C. Wolff and Andrew Fraknoi; 10. Poster highlights: astronomy education research; Part III. Educating Students: Preface; 11. Textbooks for K-12 astronomy Jay M. Pasachoff; 12. Distance/internet astronomy education David H. McKinnon; 13. Educating students with robotic telescopes - open discussion; 14. Poster highlights - educating students; Part IV. Educating teachers: Preface; 15. Pre-service astronomy education of teachers Mary Kay Hemenway; 16. In-service education of teachers Michèle Gerbaldi; 17. Poster highlights: educating teachers; Part V. Astronomy and Pseudoscience: Preface; 18. Astronomy, pseudoscience and rational thinking Jayant V. Narlikar; 19. Astronomical pseudosciences in North America John R. Percy and Jay M. Pasachoff; Part VI. Astronomy and Culture: Preface; 20. Teaching astronomy in other cultures: archeoastronomy Julieta Fierro; 21. Poster highlights: astronomy and culture; Part VII. Astronomy in Developing Countries: Preface; 22. Astronomy Curriculum for developing countries Case Rijsdijk; 23. Science education resources for the developing countries James C. White II; Part VIII. Public Outreach in Astronomy: Preface; 24. What makes informal education programs successful? Nahide Craig and Isabel

  20. Instructional methods and cognitive and learning styles in web-based learning: report of two randomised trials.

    Science.gov (United States)

    Cook, David A; Gelula, Mark H; Dupras, Denise M; Schwartz, Alan

    2007-09-01

    Adapting web-based (WB) instruction to learners' individual differences may enhance learning. Objectives This study aimed to investigate aptitude-treatment interactions between learning and cognitive styles and WB instructional methods. We carried out a factorial, randomised, controlled, crossover, post-test-only trial involving 89 internal medicine residents, family practice residents and medical students at 2 US medical schools. Parallel versions of a WB course in complementary medicine used either active or reflective questions and different end-of-module review activities ('create and study a summary table' or 'study an instructor-created table'). Participants were matched or mismatched to question type based on active or reflective learning style. Participants used each review activity for 1 course module (crossover design). Outcome measurements included the Index of Learning Styles, the Cognitive Styles Analysis test, knowledge post-test, course rating and preference. Post-test scores were similar for matched (mean +/- standard error of the mean 77.4 +/- 1.7) and mismatched (76.9 +/- 1.7) learners (95% confidence interval [CI] for difference - 4.3 to 5.2l, P = 0.84), as were course ratings (P = 0.16). Post-test scores did not differ between active-type questions (77.1 +/- 2.1) and reflective-type questions (77.2 +/- 1.4; P = 0.97). Post-test scores correlated with course ratings (r = 0.45). There was no difference in post-test subscores for modules completed using the 'construct table' format (78.1 +/- 1.4) or the 'table provided' format (76.1 +/- 1.4; CI - 1.1 to 5.0, P = 0.21), and wholist and analytic styles had no interaction (P = 0.75) or main effect (P = 0.18). There was no association between activity preference and wholist or analytic scores (P = 0.37). Cognitive and learning styles had no apparent influence on learning outcomes. There were no differences in outcome between these instructional methods.

  1. Tartu Jaani kiriku skulptuuride konserveerimisest / Eve Alttoa

    Index Scriptorium Estoniae

    Alttoa, Eve

    2006-01-01

    Terrakotaskulptuuridest, nende seisundist, terrakotaskulptuuride konserveerimise metoodika väljatöötamisest, Saksamaa abist, fassaadi- ja interjööriskulptuuridest. Fasaadiskulptuuride koopiad on valmistanud skulptuurirestauraatorid Isabel Aaso ja Alesh Zahradnik. Fassaadil on ka August Volzi aastail 1899-1904 tehtud koopiad. Bibliograafia lk. 16

  2. (SSR) and inter simple sequence repeat (ISSR)

    African Journals Online (AJOL)

    MRT

    2012-07-12

    Jul 12, 2012 ... E-mail: msheidai@yahoo.com, msheidai@sbu.ac.ir. Tel: +98 ... Stewart, 1997; Van Esbroeck and Bowman, 1998; Kumar et al., 2003 ..... Isabel N, Tremblay L, Michaud M, Tremblay FM, Bousquet J (1993). RAPDs as an aid to ...

  3. Arcillas y biocarbones para la eliminación de contaminantes de origen agrícola en aguas: ensayo en filtro a escala precomercial

    OpenAIRE

    Durán, Esperanza

    2017-01-01

    297 páginas.-- Tesis para obtener el título de Doctor por la Universidad de Sevilla con la calificación de Sobresaliente Cum laude.-- Tutora: Dra. Isabel González Díez, Profesora Titular de la Universidad de Sevilla

  4. Vulture News

    African Journals Online (AJOL)

    ... underutilized samples for detecting organophosphorus and carbamate pesticide poisoning in raptors · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ngaio Richards, Irene Zorrilla, Joseph Lalah, Peter Otieno, Isabel Fernandez, Monica Calvino, Joaquin Garcia ...

  5. Vulture News - Vol 72 (2017)

    African Journals Online (AJOL)

    ... but underutilized samples for detecting organophosphorus and carbamate pesticide poisoning in raptors · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ngaio Richards, Irene Zorrilla, Joseph Lalah, Peter Otieno, Isabel Fernandez, Monica Calvino, Joaquin Garcia ...

  6. Riskantne 21. sajandi äri / Isabel Frommelt

    Index Scriptorium Estoniae

    Frommelt, Isabel

    2004-01-01

    Artiklis otsitakse vastust küsimustele, kuidas ettevõtted saaksid anda panuse julgeoleku suurendamisse, eriti seoses terrorismiohu vähendamisega ja kas äritegevus toimib endiselt tavapäraselt või on see nüüd riskantsem

  7. Readiness of Adults to Learn Using E-Learning, M-Learning and T-Learning Technologies

    Science.gov (United States)

    Vilkonis, Rytis; Bakanoviene, Tatjana; Turskiene, Sigita

    2013-01-01

    The article presents results of the empirical research revealing readiness of adults to participate in the lifelong learning process using e-learning, m-learning and t-learning technologies. The research has been carried out in the framework of the international project eBig3 aiming at development a new distance learning platform blending virtual…

  8. Effects of Multimodal Information on Learning Performance and Judgment of Learning

    Science.gov (United States)

    Chen, Gongxiang; Fu, Xiaolan

    2003-01-01

    Two experiments were conducted to investigate the effects of multimodal information on learning performance and judgment of learning (JOL). Experiment 1 examined the effects of representation type (word-only versus word-plus-picture) and presentation channel (visual-only versus visual-plus-auditory) on recall and immediate-JOL in fixed-rate…

  9. Learning and Study Strategies Inventory subtests and factors as predictors of National Board of Chiropractic Examiners Part 1 examination performance.

    Science.gov (United States)

    Schutz, Christine M; Dalton, Leanne; Tepe, Rodger E

    2013-01-01

    This study was designed to extend research on the relationship between chiropractic students' learning and study strategies and national board examination performance. Sixty-nine first trimester chiropractic students self-administered the Learning and Study Strategies Inventory (LASSI). Linear trends tests (for continuous variables) and Mantel-Haenszel trend tests (for categorical variables) were utilized to determine if the 10 LASSI subtests and 3 factors predicted low, medium and high levels of National Board of Chiropractic Examiners (NBCE) Part 1 scores. Multiple regression was performed to predict overall mean NBCE examination scores using the 3 LASSI factors as predictor variables. Four LASSI subtests (Anxiety, Concentration, Selecting Main Ideas, Test Strategies) and one factor (Goal Orientation) were significantly associated with NBCE examination levels. One factor (Goal Orientation) was a significant predictor of overall mean NBCE examination performance. Learning and study strategies are predictive of NBCE Part 1 examination performance in chiropractic students. The current study found LASSI subtests Anxiety, Concentration, Selecting Main Ideas, and Test Strategies, and the Goal-Orientation factor to be significant predictors of NBCE scores. The LASSI may be useful to educators in preparing students for academic success. Further research is warranted to explore the effects of learning and study strategies training on GPA and NBCE performance.

  10. Students as Learning Designers

    DEFF Research Database (Denmark)

    Levinsen, Karin; Sørensen, Birgitte Holm

    2013-01-01

    This paper focuses on students in the youngest classes at primary school as learning designers of ICT-integrated productions. It is based on the project Netbook 1:1 (2009-2012) funded by the municipality of Gentofte and Microsoft Denmark. The paper presents a model for designing ICT-integrated st......This paper focuses on students in the youngest classes at primary school as learning designers of ICT-integrated productions. It is based on the project Netbook 1:1 (2009-2012) funded by the municipality of Gentofte and Microsoft Denmark. The paper presents a model for designing ICT......-integrated student productions which was developed during the project in relation to different subjects. Ownership, iteration and feedforward are the central concepts in this model. Two exemplary cases are presented illustrating the students’ and teachers’ roles as learning designers in relation to the model...

  11. Machine learning of molecular properties: Locality and active learning

    Science.gov (United States)

    Gubaev, Konstantin; Podryabinkin, Evgeny V.; Shapeev, Alexander V.

    2018-06-01

    In recent years, the machine learning techniques have shown great potent1ial in various problems from a multitude of disciplines, including materials design and drug discovery. The high computational speed on the one hand and the accuracy comparable to that of density functional theory on another hand make machine learning algorithms efficient for high-throughput screening through chemical and configurational space. However, the machine learning algorithms available in the literature require large training datasets to reach the chemical accuracy and also show large errors for the so-called outliers—the out-of-sample molecules, not well-represented in the training set. In the present paper, we propose a new machine learning algorithm for predicting molecular properties that addresses these two issues: it is based on a local model of interatomic interactions providing high accuracy when trained on relatively small training sets and an active learning algorithm of optimally choosing the training set that significantly reduces the errors for the outliers. We compare our model to the other state-of-the-art algorithms from the literature on the widely used benchmark tests.

  12. A justiça e a produção do direito em Castela no século XV = Justice and Law production in Castille in Century XV

    Directory of Open Access Journals (Sweden)

    Vidotte, Adriana

    2011-01-01

    Full Text Available O reinado dos Reis Católicos – Fernando de Aragão e Isabel de Castela – (1474-1504 se situa no período de transição da Idade Média para a Idade Moderna e foi considerado um período de paz e justiça em Castela. Isto nos possibilita questionar sobre as implicações, para o direito, da organização de um reino em uma era de transição. Propomos verificar o que caracteriza a passagem de um direito medieval para um direito moderno, e quais os elementos que indicam essa transição no governo dos Reis Católicos. Enfatizamos duas prerrogativas principais, uma de tradição medieval, a de juiz, e outra de caráter moderno, a legislativa, que se encerram na figuras de Fernando e Isabel

  13. Machine learning for evolution strategies

    CERN Document Server

    Kramer, Oliver

    2016-01-01

    This book introduces numerous algorithmic hybridizations between both worlds that show how machine learning can improve and support evolution strategies. The set of methods comprises covariance matrix estimation, meta-modeling of fitness and constraint functions, dimensionality reduction for search and visualization of high-dimensional optimization processes, and clustering-based niching. After giving an introduction to evolution strategies and machine learning, the book builds the bridge between both worlds with an algorithmic and experimental perspective. Experiments mostly employ a (1+1)-ES and are implemented in Python using the machine learning library scikit-learn. The examples are conducted on typical benchmark problems illustrating algorithmic concepts and their experimental behavior. The book closes with a discussion of related lines of research.

  14. Developing physics learning media using 3D cartoon

    Science.gov (United States)

    Wati, M.; Hartini, S.; Hikmah, N.; Mahtari, S.

    2018-03-01

    This study focuses on developing physics learning media using 3D cartoon on the static fluid topic. The purpose of this study is to describe: (1) the validity of the learning media, (2) the practicality of the learning media, and (3) the effectiveness of the learning media. This study is a research and development using ADDIE model. The subject of the implementation of media used class XI Science of SMAN 1 Pulau Laut Timur. The data were obtained from the validation sheet of the learning media, questionnaire, and the test of learning outcomes. The results showed that: (1) the validity of the media category is valid, (2) the practicality of the media category is practice, and (3) the effectiveness of the media category is effective. It is concluded that the learning using 3D cartoon on the static fluid topic is eligible to use in learning.

  15. A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory

    DEFF Research Database (Denmark)

    Haditsch, Ursula; Leone, Dino P; Farinelli, Mélissa

    2009-01-01

    in excitatory neurons in the forebrain in vivo not only affects spine structure, but also impairs synaptic plasticity in the hippocampus with consequent defects in hippocampus-dependent spatial learning. Furthermore, Rac1 mutants display deficits in working/episodic-like memory in the delayed matching...

  16. Development of an e-learning package on Service-Learning for university teachers: experience from Hong Kong.

    Science.gov (United States)

    Shek, Daniel T L; Chan, Stephen C F

    2013-01-01

    To help university teachers to understand Service-Learning and develop Service-Learning subjects, a 3-h+ e-learning package was developed at The Hong Kong Polytechnic University (PolyU). There are seven units in this e-learning package: introduction session (Unit 1), what is Service-Learning? (Unit 2), impact and benefits of Service-Learning (Unit 3), myths and positive attitudes toward Service-Learning (Unit 4), developing a Service-Learning subject at PolyU (Unit 5), self-reflection about Service-Learning (Unit 6), and concluding session (Unit 7). To understand the views of the users on the e-learning package, the package was offered before formal launching. For the first offering, three focus group sessions were held. Results showed that the users were satisfied with the structural arrangement of the e-learning package and agreed that the e-learning package was useful for them to understand more about Service-Learning. For the second offering, colleagues were generally satisfied with the e-learning package and demonstrated gain in knowledge on Service-Learning. Suggestions for improvement were noted.

  17. Characteristics and Consequences of Adult Learning Methods and Strategies. Practical Evaluation Reports, Volume 2, Number 1

    Science.gov (United States)

    Trivette, Carol M.; Dunst, Carl J.; Hamby, Deborah W.; O'Herin, Chainey E.

    2009-01-01

    The effectiveness of four adult learning methods (accelerated learning, coaching, guided design, and just-in-time training) constituted the focus of this research synthesis. Findings reported in "How People Learn" (Bransford et al., 2000) were used to operationally define six adult learning method characteristics, and to code and analyze…

  18. eLearning--Theories, Design, Software and Applications

    Science.gov (United States)

    Ghislandi, Patrizia, Ed.

    2012-01-01

    Chapters in this book include: (1) New e-Learning Environments: e-Merging Networks in the Relational Society (Blanca C. Garcia); (2) Knowledge Building in E-Learning (Xinyu Zhang and Lu Yuhao); (3) E-Learning and Desired Learning Outcomes (Ralph Palliam); (4) Innovative E-Learning Solutions and Environments for Small and Medium Sized Companies…

  19. KINAESTHETIC LEARNING STYLE AND ITS USAGE IN LEARNING PROCESS IN BASIC SCHOOL

    OpenAIRE

    Jonāne, Lolita

    2018-01-01

    The aim of the research is to explore the possibilities and methodological solutions of using kinaesthetic teaching style in the teaching/learning process in basic school and its impact on pupil involvement in learning activities and attainment of goals. Qualitative  and quantitative methods  - experienced teacher’s survey and student-trainee survey  after observation and analysys of lessons at school are used during the study. It is concluded that: 1)the kinesthetic style of learning involve...

  20. From Cloister to Commons: Concepts and Models for Service-Learning in Religious Studies. AAHE's Series on Service-Learning in the Disciplines.

    Science.gov (United States)

    Devine, Richard, Ed.; Favazza, Joseph A., Ed.; McLain, F. Michael, Ed.

    This essays in this volume, 19th in a series, discuss why and how service-learning can be implemented in Religious Studies and what that discipline contributes to the pedagogy of service-learning. Part 1, "Service-Learning and the Dilemma of Religious Studies," contains: (1) "Service-Learning and the Dilemma of Religious Studies: Descriptive or…

  1. Collaborative Learning: Cognitive and Computational Approaches. Advances in Learning and Instruction Series.

    Science.gov (United States)

    Dillenbourg, Pierre, Ed.

    Intended to illustrate the benefits of collaboration between scientists from psychology and computer science, namely machine learning, this book contains the following chapters, most of which are co-authored by scholars from both sides: (1) "Introduction: What Do You Mean by 'Collaborative Learning'?" (Pierre Dillenbourg); (2)…

  2. From learning objects to learning activities

    DEFF Research Database (Denmark)

    Dalsgaard, Christian

    2005-01-01

    This paper discusses and questions the current metadata standards for learning objects from a pedagogical point of view. From a social constructivist approach, the paper discusses how learning objects can support problem based, self-governed learning activities. In order to support this approach......, it is argued that it is necessary to focus on learning activities rather than on learning objects. Further, it is argued that descriptions of learning objectives and learning activities should be separated from learning objects. The paper presents a new conception of learning objects which supports problem...... based, self-governed activities. Further, a new way of thinking pedagogy into learning objects is introduced. It is argued that a lack of pedagogical thinking in learning objects is not solved through pedagogical metadata. Instead, the paper suggests the concept of references as an alternative...

  3. Motivation, students' needs and learning outcomes: a hybrid game-based app for enhanced language learning.

    Science.gov (United States)

    Berns, Anke; Isla-Montes, José-Luis; Palomo-Duarte, Manuel; Dodero, Juan-Manuel

    2016-01-01

    In the context of European Higher Education students face an increasing focus on independent, individual learning-at the expense of face-to-face interaction. Hence learners are, all too often, not provided with enough opportunities to negotiate in the target language. The current case study aims to address this reality by going beyond conventional approaches to provide students with a hybrid game-based app, combining individual and collaborative learning opportunities. The 4-week study was carried out with 104 German language students (A1.2 CEFR) who had previously been enrolled in a first-semester A1.1 level course at a Spanish university. The VocabTrainerA1 app-designed specifically for this study-harnesses the synergy of combining individual learning tasks and a collaborative murder mystery game in a hybrid level-based architecture. By doing so, the app provides learners with opportunities to apply their language skills to real-life-like communication. The purpose of the study was twofold: on one hand we aimed to measure learner motivation, perceived usefulness and added value of hybrid game-based apps; on the other, we sought to determine their impact on language learning. To this end, we conducted focus group interviews and an anonymous Technology Acceptance Model survey (TAM). In addition, students took a pre-test and a post-test. Scores from both tests were compared with the results obtained in first-semester conventional writing tasks, with a view to measure learning outcomes. The study provides qualitative and quantitative data supporting our initial hypotheses. Our findings suggest that hybrid game-based apps like VocabTrainerA1-which seamlessly combine individual and collaborative learning tasks-motivate learners, stimulate perceived usefulness and added value, and better meet the language learning needs of today's digital natives. In terms of acceptance, outcomes and sustainability, the data indicate that hybrid game-based apps significantly improve

  4. Can machine learning explain human learning?

    NARCIS (Netherlands)

    Vahdat, M.; Oneto, L.; Anguita, D.; Funk, M.; Rauterberg, G.W.M.

    2016-01-01

    Learning Analytics (LA) has a major interest in exploring and understanding the learning process of humans and, for this purpose, benefits from both Cognitive Science, which studies how humans learn, and Machine Learning, which studies how algorithms learn from data. Usually, Machine Learning is

  5. Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening.

    Science.gov (United States)

    Deshmukh, Amit Laxmikant; Chandra, Sharat; Singh, Deependra Kumar; Siddiqi, Mohammad Imran; Banerjee, Dibyendu

    2017-07-25

    Human Flap endonuclease1 (FEN1) is an enzyme that is indispensable for DNA replication and repair processes and inhibition of its Flap cleavage activity results in increased cellular sensitivity to DNA damaging agents (cisplatin, temozolomide, MMS, etc.), with the potential to improve cancer prognosis. Reports of the high expression levels of FEN1 in several cancer cells support the idea that FEN1 inhibitors may target cancer cells with minimum side effects to normal cells. In this study, we used large publicly available, high-throughput screening data of small molecule compounds targeted against FEN1. Two machine learning algorithms, Support Vector Machine (SVM) and Random Forest (RF), were utilized to generate four classification models from huge PubChem bioassay data containing probable FEN1 inhibitors and non-inhibitors. We also investigated the influence of randomly selected Zinc-database compounds as negative data on the outcome of classification modelling. The results show that the SVM model with inactive compounds was superior to RF with Matthews's correlation coefficient (MCC) of 0.67 for the test set. A Maybridge database containing approximately 53 000 compounds was screened and top ranking 5 compounds were selected for enzyme and cell-based in vitro screening. The compound JFD00950 was identified as a novel FEN1 inhibitor with in vitro inhibition of flap cleavage activity as well as cytotoxic activity against a colon cancer cell line, DLD-1.

  6. Education for a Learning Society.

    Science.gov (United States)

    Tempero, Howard E., Ed.

    The essays contained in this booklet are 1) "Education for a 'Learning Society': The Challenge" by Ernest Bayles in which he calls for focus on learning to live, developing skills of reflection and judgment applicable to vital issues, and reflective teaching; 2) "Teacher Education in a Learning Society" in which David Turney demands teacher…

  7. The Effects of Giving and Receiving Marginal L1 Glosses on L2 Vocabulary Learning by Upper Secondary Learners

    Science.gov (United States)

    Samian, Hosein Vafadar; Foo, Thomas Chow Voon; Mohebbi, Hassan

    2016-01-01

    This paper reports the findings of a study that investigated the effect of giving and receiving marginal L1 glosses on L2 vocabulary learning. To that end, forty nine Iranian learners of English were assigned to three different experimental conditions including marginal L1 glosses Giver (n = 17), marginal L1 glosses Receiver (n = 17), and no…

  8. E-Learning 2.0: Learning Redefined

    OpenAIRE

    Kumar, Rupesh

    2009-01-01

    The conventional e-learning approach emphasizes a learning system more than a learning environment. While traditional e-learning systems continue to be significant, there is a new set of services emerging, embracing the philosophy of Web 2.0. Known as e-learning 2.0, it aims to create a personalized learning environment. E-learning 2.0 combines the use of discrete but complementary tools and web services to support the creation of ad-hoc learning communities. This paper discusses the influenc...

  9. The Case for Case-Based Transfer Learning

    Science.gov (United States)

    2011-01-01

    Thorndike and Woodworth 1901; Perkins and Salomon 1994; Bransford, Brown, and Cocking 2000), among other disciplines. Transfer learning uses knowledge...Transfer Learning for Rein- forcement Learning Domains: A Survey. Journal of Machine Learning Research 10(1): 1633–1685. Thorndike , E. L., and

  10. Model brain based learning (BBL and whole brain teaching (WBT in learning

    Directory of Open Access Journals (Sweden)

    Baiq Sri Handayani

    2017-08-01

    Full Text Available The learning process is a process of change in behavior as a form of the result of learning. The learning model is a crucial component of the success of the learning process. The learning model is growing fastly, and each model has different characteristics. Teachers are required to be able to understand each model to teach the students optimally by matching the materials and the learning model. The best of the learning model is the model that based on the brain system in learning that are the model of Brain Based Learning (BBL and the model of Whole Brain Teaching (WBT. The purposes of this article are to obtain information related to (1 the brain’s natural learning system, (2 analyze the characteristics of the model BBL and WBT based on theory, brain sections that play a role associated with syntax, similarities, and differences, (3 explain the distinctive characteristics of both models in comparison to other models. The results of this study are: (1 the brain’s natural learning system are: (a the nerves in each hemisphere do not work independently, (b doing more activities can connect more brain nerves, (c the right hemisphere controls the left side motoric sensor of the body, and vice versa; (2 the characteristics of BBL and WBT are: (a BBL is based on the brain’s structure and function, while the model WBT is based on the instructional approach, neurolinguistic, and body language, (b the parts of the brain that work in BBL are: cerebellum, cerebral cortex, frontal lobe, limbic system, and prefrontal cortex; whereas the parts that work WBT are: prefrontal cortex, visual cortex, motor cortex, limbic system, and amygdala, (c the similarities between them are that they both rely on the brain’s system and they both promote gesture in learning, whereas the differences are on the view of the purposes of gestures and the learning theory that they rely on. BBL relies on cognitive theory while WBT relies on social theory; (3 the typical

  11. L-histidine enhances learning in stressed zebrafish

    Directory of Open Access Journals (Sweden)

    L.P.V. Cofiel

    2009-01-01

    Full Text Available The aim of the present study was to determine the effect of the histaminergic precursor L-histidine and the H3 receptor antagonist thioperamide on the learning process of zebrafish submitted or not to confinement stress. On each of the 5 consecutive days of experiment (D1, D2, D3, D4, D5, animals had to associate an interruption of the aquarium air supply with food offering. Non-stressed zebrafish received an intraperitoneal injection of 100 mg/kg L-histidine, 10 mg/kg thioperamide or saline after training. Stressed animals received drug treatment and then were submitted to confinement stress for 1 h before the learning procedure. Time to approach the feeder was measured (in seconds and was considered to be indicative of learning. A decrease in time to approach the feeder was observed in the saline-treated group (D1 = 141.92 ± 13.57; D3 = 55 ± 13.54, indicating learning. A delay in learning of stressed animals treated with saline was observed (D1 = 217.5 ± 25.66. L-histidine facilitated learning in stressed (D1 = 118.68 ± 13.9; D2 = 45.88 ± 8.2 and non-stressed (D1 = 151.11 ± 19.20; D5 = 62 ± 14.68 animals. Thioperamide inhibited learning in non-stressed (D1 = 110.38 ± 9.49; D4 = 58.79 ± 16.83 and stressed animals (D1 = 167.3 ± 26.39; D5 = 172.15 ± 27.35. L-histidine prevented the increase in blood glucose after one session of confinement (L-histidine = 65.88 ± 4.50; control = 53 ± 3.50 mg/dL. These results suggest that the histaminergic system enhances learning and modulates stress responses in zebrafish.

  12. The Learning Styles and Language Learning Strategies of the EFL Students at Tertiary Level

    Directory of Open Access Journals (Sweden)

    Diemroh Ihsan

    2016-02-01

    Full Text Available The purpose of this study are to discover the learning styles, and the language learning strategies most preferred, correlation among the variables exists, and the degree of influence each independent variable exerts on the dependent variables. For data collection, the Barsch Learning Styles Inventory and the Strategy Inventory of Language Learning were distributed to 156 students of English at the University of Sriwijaya, Palembang. The results showed that: (1 visual is the most preferred learning style, whereas metacognitive ang effective are the most preferred language learning strategies; (2 certain independent variables have a significant correlation with certain dependent variables, for example, visual with memory, auditory with cognitive, tactile with affective, and semester with compensation; (3 females use a greater variety of language learning strategies than males; and (4 semester has a significant correlation with compensation but not with other strategies

  13. The Influence Of Learning Model Guided Findings Of Student Learning Outcomes

    Directory of Open Access Journals (Sweden)

    A. SaefulBahri

    2015-03-01

    Full Text Available Abstract This study examines the influence of the learning model guided findings on student learning outcomes in subjects PAI eighth grade students of SMP Plus al Masoem. The research method used in this study is a quantitative method in the form of quasi-experiment Quasi-Experimental Design. The findings of the study are expected to demonstrate 1 the difference significant increase in learning outcomes between the experimental class using guided discovery method that uses the control class discussion of learning models 2 Constraints in the method of guided discovery activities and the limited ability of educators in the experimental class in implements the method of guided discovery and constraints faced by students while digging the information they need so we need special strategies to motivate students in the experimental class in order for them creatively find the right way to gather information that supports learning PAI.

  14. Seven Affordances of Computer-Supported Collaborative Learning: How to Support Collaborative Learning? How Can Technologies Help?

    Science.gov (United States)

    Jeong, Heisawn; Hmelo-Silver, Cindy E.

    2016-01-01

    This article proposes 7 core affordances of technology for collaborative learning based on theories of collaborative learning and CSCL (Computer-Supported Collaborative Learning) practices. Technology affords learner opportunities to (1) engage in a joint task, (2) communicate, (3) share resources, (4) engage in productive collaborative learning…

  15. Approximate kernel competitive learning.

    Science.gov (United States)

    Wu, Jian-Sheng; Zheng, Wei-Shi; Lai, Jian-Huang

    2015-03-01

    Kernel competitive learning has been successfully used to achieve robust clustering. However, kernel competitive learning (KCL) is not scalable for large scale data processing, because (1) it has to calculate and store the full kernel matrix that is too large to be calculated and kept in the memory and (2) it cannot be computed in parallel. In this paper we develop a framework of approximate kernel competitive learning for processing large scale dataset. The proposed framework consists of two parts. First, it derives an approximate kernel competitive learning (AKCL), which learns kernel competitive learning in a subspace via sampling. We provide solid theoretical analysis on why the proposed approximation modelling would work for kernel competitive learning, and furthermore, we show that the computational complexity of AKCL is largely reduced. Second, we propose a pseudo-parallelled approximate kernel competitive learning (PAKCL) based on a set-based kernel competitive learning strategy, which overcomes the obstacle of using parallel programming in kernel competitive learning and significantly accelerates the approximate kernel competitive learning for large scale clustering. The empirical evaluation on publicly available datasets shows that the proposed AKCL and PAKCL can perform comparably as KCL, with a large reduction on computational cost. Also, the proposed methods achieve more effective clustering performance in terms of clustering precision against related approximate clustering approaches. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Learning while Babbling: Prelinguistic Object-Directed Vocalizations Indicate a Readiness to Learn

    Science.gov (United States)

    Goldstein, Michael H.; Schwade, Jennifer; Briesch, Jacquelyn; Syal, Supriya

    2010-01-01

    Two studies illustrate the functional significance of a new category of prelinguistic vocalizing--object-directed vocalizations (ODVs)--and show that these sounds are connected to learning about words and objects. Experiment 1 tested 12-month-old infants' perceptual learning of objects that elicited ODVs. Fourteen infants' vocalizations were…

  17. The effect of Using Mind Mapping and Learning Styles to Geography Learning outcomes of Junior High School Students

    Directory of Open Access Journals (Sweden)

    Sigit Purwoko

    2015-02-01

    Full Text Available Pengaruh Penggunaan Peta Pikiran dan Gaya Belajar terhadap Hasil Belajar Geografi Siswa SMP Abstract: This study aimed to determine the effect of the use of mind maps, learning styles and inter-action using a mind map learning style on geography learning outcomes. This study was a quasi-experimental study, with a 2 x 3 factorial design study subject consisted of two classes of class VII G as experimental class and class VII F as a control class. Variables consisted of: (1 the dependent variable is the student learning outcomes; (2 the independent variable is the use of mind maps; and (3 is the moderator variable learning styles. Geography learning outcomes were measured using an objective test, whereas learning styles with questionnaires. Measurement data are then analyzed using ANOVA two paths with SPSS v.7. Results of data analysis using ANOVA two path showed that: (1 the use of mind maps significantly effect on learning outcomes geography; (2 learning style does not significantly affect the results of learning geography; and (3 there is no interaction between the use of mind maps and learning style on learning outcomes. Key Words: mind maps, learning styles, learning outcomes   Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan peta pikiran, gaya belajar dan interaksi penggunaan peta pikiran dengan gaya belajar terhadap hasil belajar geografi. Penelitian ini merupakan penelitian eksperimen semu, dengan desain faktorial 2 x 3. Subjek penelitian terdiri dari dua kelas yaitu kelas VII G sebagai kelas eksperimen dan kelas VII F sebagai kelas kontrol. Variabel penelitian terdiri dari: (1 variabel terikat adalah hasil belajar siswa; (2 variabel bebas adalah pengguna-an peta pikiran; dan (3 variabel moderator adalah gaya belajar. Hasil belajar geografi diukur menggunakan tes objektif, sedangkan gaya belajar dengan angket. Data hasil pengukuran dianalisis menggunakan anova dua jalur dengan bantuan SPSS v.7. Hasil analisis data

  18. Learning Performance Enhancement Using Computer-Assisted Language Learning by Collaborative Learning Groups

    Directory of Open Access Journals (Sweden)

    Ya-huei Wang

    2017-08-01

    Full Text Available This study attempted to test whether the use of computer-assisted language learning (CALL and innovative collaborative learning could be more effective than the use of traditional collaborative learning in improving students’ English proficiencies. A true experimental design was used in the study. Four randomly-assigned groups participated in the study: a traditional collaborative learning group (TCLG, 34 students, an innovative collaborative learning group (ICLG, 31 students, a CALL traditional collaborative learning group (CALLTCLG, 32 students, and a CALL innovative collaborative learning group (CALLICLG, 31 students. TOEIC (Test of English for International Communication listening, reading, speaking, and writing pre-test and post-test assessments were given to all students at an interval of sixteen weeks. Multivariate analysis of covariance (MANCOVA, multivariate analysis of variance (MANOVA, and analysis of variance (ANOVA were used to analyze the data. The results revealed that students who used CALL had significantly better learning performance than those who did not. Students in innovative collaborative learning had significantly better learning performances than those in traditional collaborative learning. Additionally, students using CALL innovative collaborative learning had better learning performances than those in CALL collaborative learning, those in innovative collaborative learning, and those in traditional collaborative learning.

  19. Learning styles and approaches to learning among medical undergraduates and postgraduates.

    Science.gov (United States)

    Samarakoon, Lasitha; Fernando, Tharanga; Rodrigo, Chaturaka

    2013-03-25

    The challenge of imparting a large amount of knowledge within a limited time period in a way it is retained, remembered and effectively interpreted by a student is considerable. This has resulted in crucial changes in the field of medical education, with a shift from didactic teacher centered and subject based teaching to the use of interactive, problem based, student centered learning. This study tested the hypothesis that learning styles (visual, auditory, read/write and kinesthetic) and approaches to learning (deep, strategic and superficial) differ among first and final year undergraduate medical students, and postgraduates medical trainees. We used self administered VARK and ASSIST questionnaires to assess the differences in learning styles and approaches to learning among medical undergraduates of the University of Colombo and postgraduate trainees of the Postgraduate Institute of Medicine, Colombo. A total of 147 participated: 73 (49.7%) first year students, 40 (27.2%) final year students and 34(23.1%) postgraduate students. The majority (69.9%) of first year students had multimodal learning styles. Among final year students, the majority (67.5%) had multimodal learning styles, and among postgraduates, the majority were unimodal (52.9%) learners.Among all three groups, the predominant approach to learning was strategic. Postgraduates had significant higher mean scores for deep and strategic approaches than first years or final years (p learning approaches suggest a positive shift towards deep and strategic learning in postgraduate students. However a similar difference was not observed in undergraduate students from first year to final year, suggesting that their curriculum may not have influenced learning methodology over a five year period.

  20. Learning in the machine: The symmetries of the deep learning channel.

    Science.gov (United States)

    Baldi, Pierre; Sadowski, Peter; Lu, Zhiqin

    2017-11-01

    In a physical neural system, learning rules must be local both in space and time. In order for learning to occur, non-local information must be communicated to the deep synapses through a communication channel, the deep learning channel. We identify several possible architectures for this learning channel (Bidirectional, Conjoined, Twin, Distinct) and six symmetry challenges: (1) symmetry of architectures; (2) symmetry of weights; (3) symmetry of neurons; (4) symmetry of derivatives; (5) symmetry of processing; and (6) symmetry of learning rules. Random backpropagation (RBP) addresses the second and third symmetry, and some of its variations, such as skipped RBP (SRBP) address the first and the fourth symmetry. Here we address the last two desirable symmetries showing through simulations that they can be achieved and that the learning channel is particularly robust to symmetry variations. Specifically, random backpropagation and its variations can be performed with the same non-linear neurons used in the main input-output forward channel, and the connections in the learning channel can be adapted using the same algorithm used in the forward channel, removing the need for any specialized hardware in the learning channel. Finally, we provide mathematical results in simple cases showing that the learning equations in the forward and backward channels converge to fixed points, for almost any initial conditions. In symmetric architectures, if the weights in both channels are small at initialization, adaptation in both channels leads to weights that are essentially symmetric during and after learning. Biological connections are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Guided discovery learning in geometry learning

    Science.gov (United States)

    Khasanah, V. N.; Usodo, B.; Subanti, S.

    2018-03-01

    Geometry is a part of the mathematics that must be learned in school. The purpose of this research was to determine the effect of Guided Discovery Learning (GDL) toward geometry learning achievement. This research had conducted at junior high school in Sukoharjo on academic years 2016/2017. Data collection was done based on student’s work test and documentation. Hypothesis testing used two ways analysis of variance (ANOVA) with unequal cells. The results of this research that GDL gave positive effect towards mathematics learning achievement. GDL gave better mathematics learning achievement than direct learning. There was no difference of mathematics learning achievement between male and female. There was no an interaction between sex differences and learning models toward student’s mathematics learning achievement. GDL can be used to improve students’ mathematics learning achievement in geometry.

  2. Assessment of first-year medical students' perceptions of teaching and learning through team-based learning sessions.

    Science.gov (United States)

    Obad, Adam S; Peeran, Ahmed A; Shareef, Mohammad Abrar; Alsheikh, Wissal J; Kalagi, Dana A; AlAmodi, Abdulhadi A; Khan, Tehreem A; Shaikh, Abdul Ahad; Ganguly, Paul; Yaqinuddin, Ahmed

    2016-12-01

    Team-based learning (TBL) is an emerging teaching and learning strategy being employed in medical schools. The College of Medicine at Alfaisal University has adopted a TBL approach as an instructional method for first-year medical students. The aim of the present study was to describe the TBL method employed at Alfaisal University College of Medicine and to assess first-year medical students' perceptions of this learning modality for the anatomy- and physiology-based blocks/courses in organ systems form of curriculum. A five-point Likert scale questionnaire was structured based on Kirkpatrick's theory and assessed three major domains: reaction, learning, and behavior. Confirmatory factor analysis (CFA) and Cronbach's α-coefficient tests were used to assess the validity and reliability of the construct, respectively. CFA showed an adequate validity of the survey and Cronbach's α revealed an acceptable internal uniformity (0.69). A total of 185 respondents rated reaction, learning, and behavior toward introduction of TBL as 3.53 ± 1.01, 3.59 ± 1.12, and 3.57 ± 1.12, respectively. Excellent students rated TBL highly in all major domains compared with borderline students (reaction, behavior, and learning domains with P values of teaching and learning strategy for functional anatomy, and prior involvement in teamwork and academic performance correlates with higher ratings of TBL. Copyright © 2016 the American Physiological Society.

  3. DAT1-Genotype and Menstrual Cycle, but Not Hormonal Contraception, Modulate Reinforcement Learning: Preliminary Evidence.

    Science.gov (United States)

    Jakob, Kristina; Ehrentreich, Hanna; Holtfrerich, Sarah K C; Reimers, Luise; Diekhof, Esther K

    2018-01-01

    Hormone by genotype interactions have been widely ignored by cognitive neuroscience. Yet, the dependence of cognitive performance on both baseline dopamine (DA) and current 17ß-estradiol (E2) level argues for their combined effect also in the context of reinforcement learning. Here, we assessed how the interaction between the natural rise of E2 in the late follicular phase (FP) and the 40 base-pair variable number tandem repeat polymorphism of the dopamine transporter (DAT1) affects reinforcement learning capacity. 30 women with a regular menstrual cycle performed a probabilistic feedback learning task twice during the early and late FP. In addition, 39 women, who took hormonal contraceptives (HC) to suppress natural ovulation, were tested during the "pill break" and the intake phase of HC. The present data show that DAT1-genotype may interact with transient hormonal state, but only in women with a natural menstrual cycle. We found that carriers of the 9-repeat allele (9RP) experienced a significant decrease in the ability to avoid punishment from early to late FP. Neither homozygote subjects of the 10RP allele, nor subjects from the HC group showed a change in behavior between phases. These data are consistent with neurobiological studies that found that rising E2 may reverse DA transporter function and could enhance DA efflux, which would in turn reduce punishment sensitivity particularly in subjects with a higher transporter density to begin with. Taken together, the present results, although based on a small sample, add to the growing understanding of the complex interplay between different physiological modulators of dopaminergic transmission. They may not only point out the necessity to control for hormonal state in behavioral genetic research, but may offer new starting points for studies in clinical settings.

  4. DAT1-Genotype and Menstrual Cycle, but Not Hormonal Contraception, Modulate Reinforcement Learning: Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Kristina Jakob

    2018-02-01

    Full Text Available Hormone by genotype interactions have been widely ignored by cognitive neuroscience. Yet, the dependence of cognitive performance on both baseline dopamine (DA and current 17ß-estradiol (E2 level argues for their combined effect also in the context of reinforcement learning. Here, we assessed how the interaction between the natural rise of E2 in the late follicular phase (FP and the 40 base-pair variable number tandem repeat polymorphism of the dopamine transporter (DAT1 affects reinforcement learning capacity. 30 women with a regular menstrual cycle performed a probabilistic feedback learning task twice during the early and late FP. In addition, 39 women, who took hormonal contraceptives (HC to suppress natural ovulation, were tested during the “pill break” and the intake phase of HC. The present data show that DAT1-genotype may interact with transient hormonal state, but only in women with a natural menstrual cycle. We found that carriers of the 9-repeat allele (9RP experienced a significant decrease in the ability to avoid punishment from early to late FP. Neither homozygote subjects of the 10RP allele, nor subjects from the HC group showed a change in behavior between phases. These data are consistent with neurobiological studies that found that rising E2 may reverse DA transporter function and could enhance DA efflux, which would in turn reduce punishment sensitivity particularly in subjects with a higher transporter density to begin with. Taken together, the present results, although based on a small sample, add to the growing understanding of the complex interplay between different physiological modulators of dopaminergic transmission. They may not only point out the necessity to control for hormonal state in behavioral genetic research, but may offer new starting points for studies in clinical settings.

  5. Surgical education and adult learning: Integrating theory into practice [version 1; referees: 3 approved

    Directory of Open Access Journals (Sweden)

    Prem Rashid

    2017-02-01

    Full Text Available Surgical education continues to evolve from the master-apprentice model. Newer methods of the process need to be used to manage the dual challenges of educating while providing safe surgical care. This requires integrating adult learning concepts into delivery of practical training and education in busy clinical environments. A narrative review aimed at outlining and integrating adult learning and surgical education theory was undertaken. Additionally, this information was used to relate the practical delivery of surgical training and education in day-to-day surgical practice. Concepts were sourced from reference material. Additional material was found using a PubMed search of the words: ‘surgical education theory’ and ‘adult learning theory medical’. This yielded 1351 abstracts, of which 43 articles with a focus on key concepts in adult education theory were used. Key papers were used to formulate structure and additional cross-referenced papers were included where appropriate. Current concepts within adult learning have a lot to offer when considering how to better deliver surgical education and training. Better integration of adult learning theory can be fruitful. Individual teaching surgical units need to rethink their paradigms and consider how each individual can contribute to the education experience. Up skilling courses for trainers can do much to improve the delivery of surgical education. Understanding adult learning concepts and integrating these into day-to-day teaching can be valuable.

  6. Learning scikit-learn machine learning in Python

    CERN Document Server

    Garreta, Raúl

    2013-01-01

    The book adopts a tutorial-based approach to introduce the user to Scikit-learn.If you are a programmer who wants to explore machine learning and data-based methods to build intelligent applications and enhance your programming skills, this the book for you. No previous experience with machine-learning algorithms is required.

  7. Improving Multi-Instance Multi-Label Learning by Extreme Learning Machine

    Directory of Open Access Journals (Sweden)

    Ying Yin

    2016-05-01

    Full Text Available Multi-instance multi-label learning is a learning framework, where every object is represented by a bag of instances and associated with multiple labels simultaneously. The existing degeneration strategy-based methods often suffer from some common drawbacks: (1 the user-specific parameter for the number of clusters may incur the effective problem; (2 SVM may bring a high computational cost when utilized as the classifier builder. In this paper, we propose an algorithm, namely multi-instance multi-label (MIML-extreme learning machine (ELM, to address the problems. To our best knowledge, we are the first to utilize ELM in the MIML problem and to conduct the comparison of ELM and SVM on MIML. Extensive experiments have been conducted on real datasets and synthetic datasets. The results show that MIMLELM tends to achieve better generalization performance at a higher learning speed.

  8. [Learning strategy or strategic learning? Gender-dependent success in medical studies at the Medical University of Vienna].

    Science.gov (United States)

    Haidinger, Gerald; Mitterauer, Lukas; Rimroth, Evelyne; Frischenschlager, Oskar

    2008-01-01

    Analysis of the fact that male medical students have a higher success rate at the written test (multiple-choice questions) at the end of the first study year (SIP-1), although female students perform significantly better in school (school marks in mathematics, physics, chemistry, and English) and school performance is a positive predictor of study success. It is hypothesized that aspects of strategic learning influence study success and that sex-specific differences exist. In a prospective study including 726 medical students data on strategic learning (written questionnaire, 45 items) were collected. Factor analysis produced 11 factors, which then were related to results of SIP-1 (passed/failed), and to sex. Eight out of the 11 factors were dependent on sex or study success, four of them dependent on sex as well as study success ("confidence in success", "learning a lot and ab initio", "high learning capacity", and "distressed/diligent/aimless"). Overall, male students showed a more distinct methodical learning approach. Moreover, "learning by understanding" seems not to be relevant for study success. Gender-specific learning behaviour, which generally leads to better performance of girls in school, fails in the situation of SIP-1. Future developments of curriculum and examination system should take into account gender specific requirements.

  9. Building a Learning Profession. ACER Policy Briefs. Issue 3

    Science.gov (United States)

    Ingvarson, Lawrence

    2003-01-01

    This paper falls into two main sections: (1) an overview of contemporary research on effective professional learning for practicing educators; and (2) recommendations for action to promote effective learning for practicing educators. Three central questions guide the paper: (1) When does professional learning lead to improved learning outcomes for…

  10. Blended learning in anatomy

    DEFF Research Database (Denmark)

    Østergaard, Gert Værge; Brogner, Heidi Marie

    behind DBR is that new knowledge is generated through processes that simultaneously develop, test and improve a design, in this case, an educational design (1) The main principles used in the project is blended learning and flipped learning (2). …"I definitely learn best in practice, but the theory...... in working with the assignments in the classroom."... External assesor, observer and interviewer Based on the different evaluations, the conclusion are that the blended learning approach combined with the ‘flipped classroom’ is a very good way to learn and apply the anatomy, both for the students......The aim of the project was to bridge the gap between theory and practice by working more collaboratively, both peer-to-peer and between student and lecturer. Furthermore the aim was to create active learning environments. The methodology of the project is Design-Based Research (DBR). The idea...

  11. THE CONCEPT OF LANGUAGE LEARNING IN BEHAVIORISM PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Khoiru Rakhman Abidin

    2016-07-01

    Full Text Available The aims of the study are (1 the concepts of language learning in behaviorism perspective, (2 the relation between language and learning in behaviorism perspective, (3 the influence of behaviorism in language learning. This is a descriptive qualitative study. The results showed that (1 behaviorism theories of languages also give good contribution in language learning process that describes a child can learn language from their environments, (2 behaviorism perspective defines as change of behavior through experience, it means human learn something from their environments, (3 human uses language for communication in the world and he also spreads his culture with his language so  human gets  knowledge of language through learning.

  12. Knowledge and Learning in Engineering Practice

    DEFF Research Database (Denmark)

    Buch, Anders

    2007-01-01

    , this chapter discusses the cencept of learning and purports to theorize learning in a Social Theory of Learning (STL). The attempt to reconstruct learning in an STL addresses three main issues: an STL must try to specify the subject-world relationship, describe the 'mechanism' of learning, and identify......During the 20th century, traditional epistemological theories of knowledge have been under siege. In recent years, efforts have been made to reconstruct the concept of 'knowledge' to emphasize its contextual, situated and social character. Drawing on the results and methods of these efforts...... the 'telos' of learning. This attempt will in fact give answers to three fundamental questions: 1) What is learning? 2) How do we learn? and 3) Why do we learn? These questions are discussed in relation to engineering practices of getting to know and learning....

  13. Motivation, learning strategies, participation and medical school performance.

    Science.gov (United States)

    Stegers-Jager, Karen M; Cohen-Schotanus, Janke; Themmen, Axel P N

    2012-07-01

    Medical schools wish to better understand why some students excel academically and others have difficulty in passing medical courses. Components of self-regulated learning (SRL), such as motivational beliefs and learning strategies, as well as participation in scheduled learning activities, have been found to relate to student performance. Although participation may be a form of SRL, little is known about the relationships among motivational beliefs, learning strategies, participation and medical school performance. This study aimed to test and cross-validate a hypothesised model of relationships among motivational beliefs (value and self-efficacy), learning strategies (deep learning and resource management), participation (lecture attendance, skills training attendance and completion of optional study assignments) and Year 1 performance at medical school. Year 1 medical students in the cohorts of 2008 (n = 303) and 2009 (n = 369) completed a questionnaire on motivational beliefs and learning strategies (sourced from the Motivated Strategies for Learning Questionnaire) and participation. Year 1 performance was operationalised as students' average Year 1 course examination grades. Structural equation modelling was used to analyse the data. Participation and self-efficacy beliefs were positively associated with Year 1 performance (β = 0.78 and β = 0.19, respectively). Deep learning strategies were negatively associated with Year 1 performance (β =- 0.31), but positively related to resource management strategies (β = 0.77), which, in turn, were positively related to participation (β = 0.79). Value beliefs were positively related to deep learning strategies only (β = 0.71). The overall structural model for the 2008 cohort accounted for 47% of the variance in Year 1 grade point average and was cross-validated in the 2009 cohort. This study suggests that participation mediates the relationships between motivation and learning strategies, and medical school

  14. Learning to learn in the European Reference Framework for lifelong learning

    NARCIS (Netherlands)

    Pirrie, Anne; Thoutenhoofd, Ernst D.

    2013-01-01

    This article explores the construction of learning to learn that is implicit in the document Key Competences for Lifelong LearningEuropean Reference Framework and related education policy from the European Commission. The authors argue that the hallmark of learning to learn is the development of a

  15. The relationship between learning preferences (styles and approaches) and learning outcomes among pre-clinical undergraduate medical students.

    Science.gov (United States)

    Liew, Siaw-Cheok; Sidhu, Jagmohni; Barua, Ankur

    2015-03-11

    Learning styles and approaches of individual undergraduate medical students vary considerably and as a consequence, their learning needs also differ from one student to another. This study was conducted to identify different learning styles and approaches of pre-clinical, undergraduate medical students and also to determine the relationships of learning preferences with performances in the summative examinations. A cross-sectional study was conducted among randomly selected 419 pre-clinical, undergraduate medical students of the International Medical University (IMU) in Kuala Lumpur. The number of students from Year 2 was 217 while that from Year 3 was 202. The Visual, Auditory, Read/Write, Kinesthetic (VARK) and the Approaches and Study Skills Inventory for Students (ASSIST) questionnaires were used for data collection. This study revealed that 343 students (81.9%) had unimodal learning style, while the remaining 76 (18.1%) used a multimodal learning style. Among the unimodal learners, a majority (30.1%) were of Kinesthetic (K) type. Among the middle and high achievers in summative examinations, a majority had unimodal (Kinaesthetic) learning style (30.5%) and were also strategic/deep learners (79.4%). However, the learning styles and approaches did not contribute significantly towards the learning outcomes in summative examinations. A majority of the students in this study had Unimodal (Kinesthetic) learning style. The learning preferences (styles and approaches) did not contribute significantly to the learning outcomes. Future work to re-assess the viability of these learning preferences (styles and approaches) after the incorporation of teaching-learning instructions tailored specifically to the students will be beneficial to help medical teachers in facilitating students to become more capable learners.

  16. Organizational learning in a college of nursing: A learning history.

    Science.gov (United States)

    Lyman, Bret; Cowan, Lisa A; Hoyt, Hannah C

    2018-02-01

    College of nursing leaders can foster organizational learning as a means of achieving their desired organizational outcomes. Organizational learning has not previously been studied in colleges of nursing, leaving college administrators and faculty little guidance as they strive to improve outcomes in their own colleges. The purpose of this study was to discover new insights related to organizational learning in a college of nursing. The learning history method was used to document and describe organizational learning in a college of nursing. This study was conducted with a college of nursing situated in a private, religious-based university in the western United States. Six stakeholders and 16 individuals familiar with the college's history were purposively recruited for this study. Participants included college administrators, faculty, students, alumni, and individuals with university-level responsibilities related to the college. Semi-structured interviews and college artifacts were used to gather data. Data was reviewed and themes identified through a process called "distillation." The college's vision, "Learning the Healer's Art" provides purpose and motivation within the college. Four themes provide additional insight into how the college established a learning culture and fosters behavior conducive to organizational learning: (1) Character and Quality, (2) Long-Term Perspective, (3) Collaborative Leadership and Adaptation, and (4) Mentoring. College of nursing leaders can foster organizational learning and pursue improvement within their colleges. Recommended actions include developing a shared vision for the college, building a cadre of qualified faculty and students who have strong personal character, maintaining a long-term perspective, using a collaborative approach to leadership and adaptation, and facilitating mentoring. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Blended Learning Design

    DEFF Research Database (Denmark)

    Pedersen, Lise

    2015-01-01

    University College Lillebaelt has decided that 30 percent of all educational elements must be generated as blended learning by the end of the year 2015 as part of a modernization addressing following educational needs: 1. Blended learning can help match the expectations of the future students who...... learning. 4. Blended learning can contribute to supporting and improving efficiency of educational efforts. This can for instance be done through programmes for several classes by using video conferencing, allocating traditional face to face teaching to synchronous and asynchronous study activities produce...... digital materials which can be employed didactically and reused by the teachers. This can also mean that the particular competencies which teaches have in Svendborg can be used at other locations in UCL and disseminated to a larger group of students without further costs. Educational Innovation...

  18. Deep and surface learning in problem-based learning: a review of the literature.

    Science.gov (United States)

    Dolmans, Diana H J M; Loyens, Sofie M M; Marcq, Hélène; Gijbels, David

    2016-12-01

    In problem-based learning (PBL), implemented worldwide, students learn by discussing professionally relevant problems enhancing application and integration of knowledge, which is assumed to encourage students towards a deep learning approach in which students are intrinsically interested and try to understand what is being studied. This review investigates: (1) the effects of PBL on students' deep and surface approaches to learning, (2) whether and why these effects do differ across (a) the context of the learning environment (single vs. curriculum wide implementation), and (b) study quality. Studies were searched dealing with PBL and students' approaches to learning. Twenty-one studies were included. The results indicate that PBL does enhance deep learning with a small positive average effect size of .11 and a positive effect in eleven of the 21 studies. Four studies show a decrease in deep learning and six studies show no effect. PBL does not seem to have an effect on surface learning as indicated by a very small average effect size (.08) and eleven studies showing no increase in the surface approach. Six studies demonstrate a decrease and four an increase in surface learning. It is concluded that PBL does seem to enhance deep learning and has little effect on surface learning, although more longitudinal research using high quality measurement instruments is needed to support this conclusion with stronger evidence. Differences cannot be explained by the study quality but a curriculum wide implementation of PBL has a more positive impact on the deep approach (effect size .18) compared to an implementation within a single course (effect size of -.05). PBL is assumed to enhance active learning and students' intrinsic motivation, which enhances deep learning. A high perceived workload and assessment that is perceived as not rewarding deep learning are assumed to enhance surface learning.

  19. MOBILE LEARNING: INNOVATION IN TEACHING AND LEARNING USING TELEGRAM

    Directory of Open Access Journals (Sweden)

    Zanaton H. Iksan

    2017-03-01

    Full Text Available Innovation in teaching and learning is always done by the teachers to solve the problems. Teachers could use the latest education tools as their innovation. Attendance and students’ engagement are the problems in a class and it could be overcome by using mobile learning as a teaching approach. In this case, Telegram is a tool for mobile learning. The aim of this study was to explore how Telegrams could be used in teaching and learning process. This study involved a case study approach where 31 students were the participants in the post graduate courses "Science Education and Human Development". Data were collected by Telegram discussion. This study found that several techniques can be carried out using Telegram: attendance, one way discussions, technique 1-2-3 discussion, pictures, drawing, and audio. Students responded that the teaching and learning using Telegram allow them to gain new experience, be more creative, generate spontaneous ideas, provide authentic ideas without the risk of being humiliated and encourage them to be excited as well as passionate with their learning. Compared with normal classes, all students can give ideas and the ideas were honest by themselves. This study implies that the latest innovation could solve the teaching according to the problems faced by teachers.  Except where otherwise noted, content on this site is licensed under a Creative Commons Attribution 4.0 International License

  20. Influence of additional language learning on first language learning in children with language disorders.

    Science.gov (United States)

    To, Carol K S; Law, Thomas; Li, Xin-xin

    2012-01-01

    Multilingualism can bring about various positive outcomes to typically developing children. Its effect on children with language difficulties is not yet clear. The aim of this study was to examine the effects of multilingual learning as a medium of instruction (MOI) on first language (L1) acquisition of children with language disorders (LD). Nineteen Cantonese-speaking students aged 5;8-6;8 who were diagnosed with LD were recruited from a school that used Putonghua (an alternative Chinese dialect) as the MOI when learning Chinese language and were compared with 18 age-and-gender-matched Cantonese-speaking students with LD from a school that used Cantonese as the MOI when learning Chinese language. All the students also learned English (L2) as a subject at school. Proficiency in Cantonese was tested at the beginning and the end of the semester in Grade One in terms of: (1) grammar, (2) expressive vocabulary, (3) auditory textual comprehension, (4) word definition and (5) narration. Mixed-model ANOVAs revealed an effect of time on language proficiency indicating positive gains in both groups. Interaction effects between time and group were not significant. There was a trend that children learning Putonghua showed slightly more improvement in auditory textual comprehension. Proficiency gains were similar across groups. The study found no evidence that a multilingual learning environment hinders the language proficiency in L1 in students who have LD. © 2011 Royal College of Speech and Language Therapists.

  1. Two different motor learning mechanisms contribute to learning reaching movements in a rotated visual environment [version 2; referees: 2 approved, 1 approved with reservations

    Directory of Open Access Journals (Sweden)

    Virginia Way Tong Chu

    2014-12-01

    Full Text Available Practice of movement in virtual-reality and other artificially altered environments has been proposed as a method for rehabilitation following neurological injury and for training new skills in healthy humans.  For such training to be useful, there must be transfer of learning from the artificial environment to the performance of desired skills in the natural environment.  Therefore an important assumption of such methods is that practice in the altered environment engages the same learning and plasticity mechanisms that are required for skill performance in the natural environment.  We test the hypothesis that transfer of learning may fail because the learning and plasticity mechanism that adapts to the altered environment is different from the learning mechanism required for improvement of motor skill.  In this paper, we propose that a model that separates skill learning and environmental adaptation is necessary to explain the learning and aftereffects that are observed in virtual reality experiments.  In particular, we studied the condition where practice in the altered environment should lead to correct skill performance in the original environment. Our 2-mechanism model predicts that aftereffects will still be observed when returning to the original environment, indicating a lack of skill transfer from the artificial environment to the original environment. To illustrate the model prediction, we tested 10 healthy participants on the interaction between a simple overlearned motor skill (straight hand movements to targets in different directions and an artificially altered visuomotor environment (rotation of visual feedback of the results of movement.  As predicted by the models, participants show adaptation to the altered environment and after-effects on return to the baseline environment even when practice in the altered environment should have led to correct skill performance.  The presence of aftereffect under all conditions that

  2. Neurochemical Correlates of Accumbal Dopamine D2 and Amygdaloid 5-HT1B Receptor Densities on Observational Learning of Aggression

    Science.gov (United States)

    Suzuki, Hideo; Lucas, Louis R.

    2015-01-01

    Social learning theory postulates that individuals learn to engage in aggressive behavior through observing an aggressive social model. Prior studies have shown that repeatedly observing aggression, also called “chronic passive exposure to aggression,” changes accumbal dopamine D2 receptor (D2R) and amygdaloid 5-HT1B receptor (5-HT1BR) densities in observers. But, the association between these outcomes remains unknown. Thus, our study used a rat paradigm to comprehensively examine the linkage between aggression, D2R density in the nucleus accumbens core (AcbC) and shell (AcbSh), and 5-HT1BR density in the medial (MeA), basomedial (BMA), and basolateral (BLA) amygdala following chronic passive exposure to aggression. Male Sprague-Dawley rats (N = 72) were passively exposed to either aggression or non-aggression acutely (1 day) or chronically (23 days). When observer rats were exposed to aggression chronically, they showed increased aggressive behavior and reduced D2R density in the bilateral AcbSh. On the other hand, exposure to aggression, regardless of exposure length, increased 5-HT1BR density in the bilateral BLA. Finally, low D2R in the AcbSh significantly interacted with high 5-HT1BR density in the BLA in predicting high levels of aggression in observer rats. Our results advance our understanding of the neurobiological mechanisms for observational learning of aggression, highlighting that dopamine-serotonin interaction, or AcbSh-BLA interaction, may contribute to a risk factor for aggression in observers who chronically witness aggressive interactions. PMID:25650085

  3. Effects of fluoxetine on CRF and CRF1 expression in rats exposed to the learned helplessness paradigm.

    Science.gov (United States)

    Fernández Macedo, Georgina Valeria; Cladouchos, María Laura; Sifonios, Laura; Cassanelli, Pablo Martín; Wikinski, Silvia

    2013-02-01

    Stress is a common antecedent reported by people suffering major depression. In these patients, extrahypothalamic brain areas, like the hippocampus and basolateral amygdala (BLA), have been found to be affected. The BLA synthesizes CRF, a mediator of the stress response, and projects to hippocampus. The main hippocampal target for this peptide is the CRF subtype 1 receptor (CRF1). Evidence points to a relationship between dysregulation of CRF/CRF1 extrahypothalamic signaling and depression. Because selective serotonin reuptake inhibitors (SSRIs) are the first-line pharmacological treatment for depression, we investigated the effect of chronic treatment with the SSRI fluoxetine on long-term changes in CRF/CRF1 signaling in animals showing a depressive-like behavior. Male Wistar rats were exposed to the learned helplessness paradigm (LH). After evaluation of behavioral impairment, the animals were treated with fluoxetine (10 mg/kg i.p.) or saline for 21 days. We measured BLA CRF expression with RT-PCR and CRF1 expression in CA3 and the dentate gyrus of the hippocampus with in situ hybridization. We also studied the activation of one of CRF1's major intracellular signaling targets, the extracellular signal-related kinases 1 and 2 (ERK1/2) in CA3. In saline-treated LH animals, CRF expression in the BLA increased, while hippocampal CRF1 expression and ERK1/2 activation decreased. Treatment with fluoxetine reversed the changes in CRF and CRF1 expressions, but not in ERK1/2 activation. In animals exposed to the learned helplessness paradigm, there are long-term changes in CRF and CRF1 expression that are restored with a behaviorally effective antidepressant treatment.

  4. Peer Learning and Support of Technology in an Undergraduate Biology Course to Enhance Deep Learning

    Science.gov (United States)

    Tsaushu, Masha; Tal, Tali; Sagy, Ornit; Kali, Yael; Gepstein, Shimon; Zilberstein, Dan

    2012-01-01

    This study offers an innovative and sustainable instructional model for an introductory undergraduate course. The model was gradually implemented during 3 yr in a research university in a large-lecture biology course that enrolled biology majors and nonmajors. It gives priority to sources not used enough to enhance active learning in higher education: technology and the students themselves. Most of the lectures were replaced with continuous individual learning and 1-mo group learning of one topic, both supported by an interactive online tutorial. Assessment included open-ended complex questions requiring higher-order thinking skills that were added to the traditional multiple-choice (MC) exam. Analysis of students’ outcomes indicates no significant difference among the three intervention versions in the MC questions of the exam, while students who took part in active-learning groups at the advanced version of the model had significantly higher scores in the more demanding open-ended questions compared with their counterparts. We believe that social-constructivist learning of one topic during 1 mo has significantly contributed to student deep learning across topics. It developed a biological discourse, which is more typical to advanced stages of learning biology, and changed the image of instructors from “knowledge transmitters” to “role model scientists.” PMID:23222836

  5. Peer learning and support of technology in an undergraduate biology course to enhance deep learning.

    Science.gov (United States)

    Tsaushu, Masha; Tal, Tali; Sagy, Ornit; Kali, Yael; Gepstein, Shimon; Zilberstein, Dan

    2012-01-01

    This study offers an innovative and sustainable instructional model for an introductory undergraduate course. The model was gradually implemented during 3 yr in a research university in a large-lecture biology course that enrolled biology majors and nonmajors. It gives priority to sources not used enough to enhance active learning in higher education: technology and the students themselves. Most of the lectures were replaced with continuous individual learning and 1-mo group learning of one topic, both supported by an interactive online tutorial. Assessment included open-ended complex questions requiring higher-order thinking skills that were added to the traditional multiple-choice (MC) exam. Analysis of students' outcomes indicates no significant difference among the three intervention versions in the MC questions of the exam, while students who took part in active-learning groups at the advanced version of the model had significantly higher scores in the more demanding open-ended questions compared with their counterparts. We believe that social-constructivist learning of one topic during 1 mo has significantly contributed to student deep learning across topics. It developed a biological discourse, which is more typical to advanced stages of learning biology, and changed the image of instructors from "knowledge transmitters" to "role model scientists."

  6. Validation to Portuguese of the Scale of Student Satisfaction and Self-Confidence in Learning1

    Science.gov (United States)

    Almeida, Rodrigo Guimarães dos Santos; Mazzo, Alessandra; Martins, José Carlos Amado; Baptista, Rui Carlos Negrão; Girão, Fernanda Berchelli; Mendes, Isabel Amélia Costa

    2015-01-01

    Objective: translate and validate to Portuguese the Scale of Student Satisfaction and Self-Confidence in Learning. Material and Methods: methodological translation and validation study of a research tool. After following all steps of the translation process, for the validation process, the event III Workshop Brazil - Portugal: Care Delivery to Critical Patients was created, promoted by one Brazilian and another Portuguese teaching institution. Results: 103 nurses participated. As to the validity and reliability of the scale, the correlation pattern between the variables, the sampling adequacy test (Kaiser-Meyer-Olkin) and the sphericity test (Bartlett) showed good results. In the exploratory factorial analysis (Varimax), item 9 behaved better in factor 1 (Satisfaction) than in factor 2 (Self-confidence in learning). The internal consistency (Cronbach's alpha) showed coefficients of 0.86 in factor 1 with six items and 0.77 for factor 2 with 07 items. Conclusion: in Portuguese this tool was called: Escala de Satisfação de Estudantes e Autoconfiança na Aprendizagem. The results found good psychometric properties and a good potential use. The sampling size and specificity are limitations of this study, but future studies will contribute to consolidate the validity of the scale and strengthen its potential use. PMID:26625990

  7. Comportamento da área foliar da videira “Isabel” submetida a diferentes tipos e doses de biofertilizantes

    Directory of Open Access Journals (Sweden)

    Olivânia dos Santos Nascimento

    2014-06-01

    Full Text Available Objetivou-se verificar o efeito da aplicação de diferentes tipos e doses de biofertilizante, na área foliar da videira ‘Isabel’ em cultivo orgânico nas condições edafoclimáticas de Catolé do Rocha-PB. Estudou-se os efeitos de 5 tipos de biofertilizante biofertilizante e 8 doses na área foliar da videira ‘Isabel’ após a primeira poda de produção. O experimento foi conduzido sob condições de campo, em área pertencente à Universidade Estadual da Paraíba, Campus IV. O delineamento adotado foi o de blocos casualizados, com 40 tratamentos, no esquema fatorial 5 x 8, com 4  repetições, totalizando 160 parcelas experimentais, os tratamentos consistiram em aplicações crescentes de diferentes biofertilizante, aplicados de forma independente. O valor da área foliar unitária da videira Isabel aumentou com o incremento da dose do biofertilizante B1 até um limite ótimo de 0,93 L/planta/aplicação; o valor da área foliar unitária diminuiu com o aumento da dose do biofertilizante B1 acima do limite ótimo de 0,93 L/planta/aplicação; a utilização de biofertilizante enriquecido com farinha de rocha e leguminosa (B3 proporcionou maior área foliar unitária e área foliar da planta da videira Isabel.

  8. La presidencia de María Estela Martínez de Perón : la búsqueda de legitimidad y la descalificación del “otro” (1974-1976)

    OpenAIRE

    Napal, María Celeste

    2016-01-01

    Napal, M. C. (2016). La presidencia de María Estela Martínez de Perón: la búsqueda de legitimidad y la descalificación del “otro” (1974-1976). Divulgatio, 1(1). El presente artículo busca analizar, a través de los discursos presidenciales, la imagen que la presidente María Estela Martínez de Perón (Isabel) construye del “otro” no partidario en un contexto político en el que se ve cuestionada su propia legitimidad. Partimos de la idea de que el período de su presidencia (1° de julio de 1974...

  9. Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice.

    Science.gov (United States)

    Gajardo, Ivana; Salazar, Claudia S; Lopez-Espíndola, Daniela; Estay, Carolina; Flores-Muñoz, Carolina; Elgueta, Claudio; Gonzalez-Jamett, Arlek M; Martínez, Agustín D; Muñoz, Pablo; Ardiles, Álvaro O

    2018-01-01

    Long-term potentiation (LTP) and long-term depression (LTD) are two forms of synaptic plasticity that have been considered as the cellular substrate of memory formation. Although LTP has received considerable more attention, recent evidences indicate that LTD plays also important roles in the acquisition and storage of novel information in the brain. Pannexin 1 (Panx1) is a membrane protein that forms non-selective channels which have been shown to modulate the induction of hippocampal synaptic plasticity. Animals lacking Panx1 or blockade of Pannexin 1 channels precludes the induction of LTD and facilitates LTP. To evaluate if the absence of Panx1 also affects the acquisition of rapidly changing information we trained Panx1 knockout (KO) mice and wild type (WT) littermates in a visual and hidden version of the Morris water maze (MWM). We found that KO mice find the hidden platform similarly although slightly quicker than WT animals, nonetheless, when the hidden platform was located in the opposite quadrant (OQ) to the previous learned location, KO mice spent significantly more time in the previous quadrant than in the new location indicating that the absence of Panx1 affects the reversion of a previously acquired spatial memory. Consistently, we observed changes in the content of synaptic proteins critical to LTD, such as GluN2 subunits of N-methyl-D-aspartate receptors (NMDARs), which changed their contribution to synaptic plasticity in conditions of Panx1 ablation. Our findings give further support to the role of Panx1 channels on the modulation of synaptic plasticity induction, learning and memory processes.

  10. Loss of Transient Receptor Potential Ankyrin 1 Channel Deregulates Emotion, Learning and Memory, Cognition, and Social Behavior in Mice.

    Science.gov (United States)

    Lee, Kuan-I; Lin, Hui-Ching; Lee, Hsueh-Te; Tsai, Feng-Chuan; Lee, Tzong-Shyuan

    2017-07-01

    The transient receptor potential ankyrin 1 (TRPA1) channel is a non-selective cation channel that helps regulate inflammatory pain sensation and nociception and the development of inflammatory diseases. However, the potential role of the TRPA1 channel and the underlying mechanism in brain functions are not fully resolved. In this study, we demonstrated that genetic deletion of the TRPA1 channel in mice or pharmacological inhibition of its activity increased neurite outgrowth. In vivo study in mice provided evidence of the TRPA1 channel as a negative regulator in hippocampal functions; functional ablation of the TRPA1 channel in mice enhanced hippocampal functions, as evidenced by less anxiety-like behavior, and enhanced fear-related or spatial learning and memory, and novel location recognition as well as social interactions. However, the TRPA1 channel appears to be a prerequisite for motor function; functional loss of the TRPA1 channel in mice led to axonal bundle fragmentation, downregulation of myelin basic protein, and decreased mature oligodendrocyte population in the brain, for impaired motor function. The TRPA1 channel may play a crucial role in neuronal development and oligodendrocyte maturation and be a potential regulator in emotion, cognition, learning and memory, and social behavior.

  11. Deep Learning in Open Source Learning Streams

    DEFF Research Database (Denmark)

    Kjærgaard, Thomas

    2016-01-01

    This chapter presents research on deep learning in a digital learning environment and raises the question if digital instructional designs can catalyze deeper learning than traditional classroom teaching. As a theoretical point of departure the notion of ‘situated learning’ is utilized...... and contrasted to the notion of functionalistic learning in a digital context. The mechanism that enables deep learning in this context is ‘The Open Source Learning Stream’. ‘The Open Source Learning Stream’ is the notion of sharing ‘learning instances’ in a digital space (discussion board, Facebook group......, unistructural, multistructural or relational learning. The research concludes that ‘The Open Source Learning Stream’ can catalyze deep learning and that there are four types of ‘Open Source Learning streams’; individual/ asynchronous, individual/synchronous, shared/asynchronous and shared...

  12. Leer la interculturalidad

    Directory of Open Access Journals (Sweden)

    Carmen Servén Díez

    2010-01-01

    Full Text Available Reseña de la obra: Isabel Tejerina Lobo (Coord.. Leer la interculturalidad: una propuesta didáctica para la ESO desde la narrativa, el álbum y el teatro. Cantabria. Universidad de Cantabria-Gobierno de Cantabria. 2008. ISBN 978-84-691-5119-8

  13. 77 FR 21761 - Notice of Effectiveness of Exempt Wholesale Generator Status

    Science.gov (United States)

    2012-04-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Effectiveness of Exempt Wholesale Generator Status Docket Nos. Bishop Hill Interconnection LLC........ EG12-24-000. Tenaska Washington Partners, L.P....... EG12-25-000. Pattern Santa Isabel LLC EG12-26-000. Mariposa Energy, LLC EG12...

  14. 77 FR 25538 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate

    Science.gov (United States)

    2012-04-30

    ... ERIK PAUL FURLER NICOLAS SILVAN FURRER GAJA MARIA FURRER JONAS KEVIN FURRER SACHA GABRIELLA GAGNON... CATHERINE MARIE MILNE NATASHA JANE MIN CHRIS SHIK MIN STEVE BAE MIZRACHI ELI HAIM MONTAGUE ALEXANDRE NICOLAS... CHRISTIAN MARTIN SYZ ISABEL SUSAN TAN CHUAN LIONG TAN WEI-EE BEVERLY [[Page 25544

  15. Designing learning environments to promote student learning: ergonomics in all but name.

    Science.gov (United States)

    Smith, Thomas J

    2013-01-01

    This report introduces evidence for the conclusion that a common theme underlies almost all proposed solutions for improving the performance of K-12 students, namely their reliance on the design of educational system environments, features and operations. Two categories of design factors impacting such performance are addressed: (1) 9 factors reliably shown to have a strong influence - namely environmental design of classroom and building facilities, longer exposure to learning, cooperative learning designs, early childhood education, teaching quality, nutritional adequacy, participation in physical activity, good physical fitness, and school-community integration; and (2) 11 factors with an equivocal, varied or weak influence - classroom technology, online learning environments, smaller class size, school choice, school funding, school size, school start times, teacher training level, amount of homework, student self-confidence and informal learning. It is concluded that: (1) student learning outcomes, and more broadly the edifice of education itself, are largely defined in terms of an extensive system of design factors and conditions; (2) the time is long overdue for the educational system to acknowledge the central role of E/HF design as the major influence on student performance and learning; and (3) K-12 educators and administrators should emphasize allocation of resources to design factors reliably shown to have a strongly positive impact on student performance, but should treat expenditure on factors with equivocal, varied or weak influence on such performance with more caution and/or skepticism.

  16. ARLearn and StreetLearn software for virtual reality and augmented reality multi user learning games

    NARCIS (Netherlands)

    Ternier, Stefaan; Klemke, Roland

    2012-01-01

    Ternier, S., & Klemke, R. (2011). ARLearn and StreetLearn software for virtual reality and augmented reality multi user learning games (Version 1.0) [Software Documentation]. Heerlen, The Netherlands: Open Universiteit in the Netherlands.

  17. ARLearn and StreetLearn software for virtual reality and augmented reality multi user learning games

    NARCIS (Netherlands)

    Ternier, Stefaan; Klemke, Roland

    2012-01-01

    Ternier, S., & Klemke, R. (2011). ARLearn and StreetLearn software for virtual reality and augmented reality multi user learning games (Version 1.0) [Computer software]. Heerlen, The Netherlands: Open Universiteit in the Netherlands.

  18. IP-MLI: An Independency of Learning Materials from Platforms in a Mobile Learning using Intelligent Method

    Directory of Open Access Journals (Sweden)

    Mohammed Abdallh Otair

    2006-06-01

    Full Text Available Attempting to deliver a monolithic mobile learning system is too inflexible in view of the heterogeneous mixture of hardware and services available and the desirability of facility blended approaches to learning delivery, and how to build learning materials to run on all platforms[1]. This paper proposes a framework of mobile learning system using an intelligent method (IP-MLI . A fuzzy matching method is used to find suitable learning material design. It will provide a best matching for each specific platform type for each learner. The main contribution of the proposed method is to use software layer to insulate learning materials from device-specific features. Consequently, many versions of learning materials can be designed to work on many platform types.

  19. Effect of catalpol on senile plaques and spatial learning and memory ability in amyloid-β protein precursor/presenilin 1 double transgenic mice

    Institute of Scientific and Technical Information of China (English)

    宋冲

    2013-01-01

    Objective To investigate whether catalpol affects senile plaque formation and spatial learning and memory ability in the amyloid-βprotein precursor/presenilin 1(APP/PS1)double transgenic mice.Methods

  20. Active Learning Through Discussion in E-Learning

    OpenAIRE

    Daru Wahyuningsih

    2016-01-01

    Active learning is generally made by a lecturer in learning face to face. In the face to face learning, lecturer can implement a variety of teaching methods to make students actively involved in learning. This is different from learning that is actuating in e-learning. The main characteristic of e-learning is learning that can take place anytime and anywhere. Special strategies are needed so that lecturer can make students play an active role in the course of e-learning. Research in order to ...

  1. Workshop on the Development of the UNESCO Co-Action Learning Centre Programme (1st, Kuala Lumpur, Malaysia, November 12-18, 1992). Final Report.

    Science.gov (United States)

    National Federation of UNESCO Associations in Japan, Tokyo.

    This publication summarizes reports from a workshop to share the experience of UNESCO's literacy program and to learn about other effective experiences in literacy available in the region. The opening of the workshop and election of officers is reported. Summaries of the following reports are given: (1) the role of learning centers to achieve…

  2. Recommender Systems in Technology Enhanced Learning

    NARCIS (Netherlands)

    Manouselis, Nikos; Drachsler, Hendrik; Verbert, Katrien; Santos, Olga

    2010-01-01

    Manouselis, N., Drachsler, H., Verbert, K., & Santos, C. S. (Eds.) (2010). Recommender System in Technology Enhanced Learning. Elsevier Procedia Computer Science: Volume 1, Issue 2. Proceedings of the 1st Workshop on Recommender Systems for Technology Enhanced Learning (RecSysTEL). September, 29-30,

  3. Deepening Learning through Learning-by-Inventing

    OpenAIRE

    Apiola, Mikko; Tedre, Matti

    2013-01-01

    It has been shown that deep approaches to learning, intrinsic motivation, and self-regulated learning have strong positive effects on learning. How those pedagogical theories can be integrated in computing curricula is, however, still lacking empirically grounded analyses. This study integrated, in a robotics-based programming class, a method of learning-by-inventing, and studied its qualitative effects on students’ learning through 144 interviews. Five findings were related with learning the...

  4. Learning Low-Dimensional Metrics

    OpenAIRE

    Jain, Lalit; Mason, Blake; Nowak, Robert

    2017-01-01

    This paper investigates the theoretical foundations of metric learning, focused on three key questions that are not fully addressed in prior work: 1) we consider learning general low-dimensional (low-rank) metrics as well as sparse metrics; 2) we develop upper and lower (minimax)bounds on the generalization error; 3) we quantify the sample complexity of metric learning in terms of the dimension of the feature space and the dimension/rank of the underlying metric;4) we also bound the accuracy ...

  5. L1 French learning of L2 Spanish past tenses: L1 transfer versus aspect and interface issues

    Directory of Open Access Journals (Sweden)

    José Amenós Pons

    2017-09-01

    Full Text Available This paper examines the process of acquiring L2s that are closely related to the L1 through data on how adult French speakers learning L2 Spanish in a formal setting develop knowledge and use of past tenses in this L2. We consider the role of transfer and simplification in acquiring mental representations of the L2 grammar, specifically in the area of tense and aspect, and how learners deal with integrating grammatically encoded, lexical and discursive information, including mismatching feature combinations leading to particular inferential effects on interpretation. Data is presented on the Spanish past tenses (simple and compound past, pluperfect, imperfect and progressive forms from two tasks, an oral production filmretell and a multiple-choice interpretation task, completed by learners at A2, B1, B2 and C1 CEFR levels (N = 20-24 per level. L1 influence is progressively attenuated as proficiency increases. Difficulties were not always due to negative L1 transfer, but related also to grammar-discourse interface issues when integrating linguistic and pragmatic information in the interpretation process. This has clear implications for the teaching of closely related languages: instruction should not only focus on crosslinguistic contrasts, but also prioritize uses requiring complex interface integration, which are harder to process.

  6. Advanced Learning Technologies and Learning Networks and Their Impact on Future Aerospace Workforce

    Science.gov (United States)

    Noor, Ahmed K. (Compiler)

    2003-01-01

    This document contains the proceedings of the training workshop on Advanced Learning Technologies and Learning Networks and their impact on Future Aerospace Workforce. The workshop was held at the Peninsula Workforce Development Center, Hampton, Virginia, April 2 3, 2003. The workshop was jointly sponsored by Old Dominion University and NASA. Workshop attendees came from NASA, other government agencies, industry, and universities. The objectives of the workshop were to: 1) provide broad overviews of the diverse activities related to advanced learning technologies and learning environments, and 2) identify future directions for research that have high potential for aerospace workforce development. Eighteen half-hour overviewtype presentations were made at the workshop.

  7. Intentional Learning Vs Incidental Learning

    OpenAIRE

    Shahbaz Ahmed

    2017-01-01

    This study is conducted to demonstrate the knowledge of intentional learning and incidental learning. Hypothesis of this experiment is intentional learning is better than incidental learning, participants were demonstrated and were asked to learn the 10 non sense syllables in a specific sequence from the colored cards in the end they were asked to recall the background color of each card instead of non-sense syllables. Independent variables of the experiment are the colored cards containing n...

  8. Interactive radiological anatomy eLearning solution for first year medical students: Development, integration, and impact on learning.

    Science.gov (United States)

    Webb, Alexandra Louise; Choi, Sunhea

    2014-01-01

    A technology enhanced learning and teaching (TELT) solution, radiological anatomy (RA) eLearning, composed of a range of identification-based and guided learning activities related to normal and pathological X-ray images, was devised for the Year 1 nervous and locomotor course at the Faculty of Medicine, University of Southampton. Its effectiveness was evaluated using a questionnaire, pre- and post-tests, focus groups, summative assessment, and tracking data. Since introduced in 2009, a total of 781 students have used RA eLearning, and among them 167 Year 1 students in 2011, of whom 116 participated in the evaluation study. Students enjoyed learning (77%) with RA eLearning, found it was easy to use (81%) and actively engaged them in their learning (75%), all of which were associated to the usability, learning design of the TELT solution and its integration in the curriculum; 80% of students reported RA eLearning helped their revision of anatomy and 69% stated that it facilitated their application of anatomy in a clinical context, both of which were associated with the benefits offered by the learning and activities design. At the end of course summative assessment, student knowledge of RA eLearning relevant topics (mean 80%; SD ±16) was significantly better as compared to topics not relevant to RA eLearning (mean 63%; SD ±15) (mean difference 18%; 95% CI 15% to 20%; P < 0.001). A well designed and integrated TELT solution can be an efficient method for facilitating the application, integration, and contextualization of anatomy and radiology to create a blended learning environment. © 2013 American Association of Anatomists.

  9. Improving Student Learning Outcomes Marketing Strategy Lesson By Applying SFAE Learning Model

    Directory of Open Access Journals (Sweden)

    Winda Nur Rohmawati

    2017-11-01

    Full Text Available Research objectives for improving student learning outcomes on the subjects of marketing strategy through the implementation of model learning SFAE. This type of research this is a class action research using a qualitative approach which consists of two cycles with the subject Marketing X grade SMK YPI Darussalam 2 Cerme Gresik Regency. This research consists of four stages: (1 the Planning Act, (2 the implementation of the action, (3 observations (observation, and (4 Reflection. The result of the research shows that cognitive and affective learning outcomes of students have increased significantly.

  10. AUDIT SISTEM INFORMASI MENGGUNAKAN FRAMEWORK COBIT 4.1 PADA E-LEARNING UNISNU JEPARA

    Directory of Open Access Journals (Sweden)

    Noor Azizah

    2017-04-01

    Full Text Available Perkembangan teknologi saat ini tak bisa dibendung lagi. Kemajuan disetiap bidang tak lepas dari teknologi sebagai penunjangnya, terutama teknologi informasi. Akan tetapi hal tersebut harus dimbangi dengan adanya sebuah evaluasi atau audit terhadap sistem informasi sehingga ancaman atau kerugian dapat  dihindari  ataupun  dicegah.  Penelitian  ini  bertujuan  mengetahui  sejauh  mana  kinerja  sistem informasi pembelajaran yaitu e-learning sebagai layanan publik yang telah diterapkan pada UNISNU Jepara dan  memberikan   rekomendasi tata  kelola perbaikan setelah mengetahui kesenjangan antara tatakelola saat ini dengan tatakelola yang diharapkan sesuai dengan framework yang digunakan. Framework  yang digunakan dalam penelitian ini adalah COBIT versi 4.1 khusus pada domain Deliver and Support (DS. Teknik pengumpulan datanya dilakukan dengan wawancara dan kuisioner dengan narasumber yang telah ditentukan sesuai dengan domain dan Control Objective yang digunakan. Metode analisis data dilakukan beberapa tahap, yaitu penentuan domain, penentuan proses kontrol, penentuan indikator dan pemetaan tingkatkematangan. Hasil dari penelitian ini adalah untuk mengetahui tingkat kematangan (maturity level pada implementasi e-learning UNISNU Jepara khusus pada Domain DS, yaitu berada pada level 4 yang berarti sudah terukur dan terintegrasi antar proses yang berlangsung. Dan analisa GAP antara kondisi yang diharapkan dengan kondisi saat ini rata-rata sebesar 0,6.

  11. Intelligent fractions learning system: implementation

    CSIR Research Space (South Africa)

    Smith, Andrew C

    2011-05-01

    Full Text Available Conference Proceedings Paul Cunningham and Miriam Cunningham (Eds) IIMC International Information Management Corporation, 2011 ISBN: 978-1-905824-24-3 An Intelligent Fractions Learning System: Implementation Andrew Cyrus SMITH1, Teemu H. LAINE2 1CSIR... to fractions. Our aim with the current research project is to extend the existing UFractions learning system to incorporate automatic data capturing. ?Intelligent UFractions? allows a teacher to remotely monitor the children?s progress during...

  12. CRTC1 Nuclear Translocation Following Learning Modulates Memory Strength via Exchange of Chromatin Remodeling Complexes on the Fgf1 Gene.

    Science.gov (United States)

    Uchida, Shusaku; Teubner, Brett J W; Hevi, Charles; Hara, Kumiko; Kobayashi, Ayumi; Dave, Rutu M; Shintaku, Tatsushi; Jaikhan, Pattaporn; Yamagata, Hirotaka; Suzuki, Takayoshi; Watanabe, Yoshifumi; Zakharenko, Stanislav S; Shumyatsky, Gleb P

    2017-01-10

    Memory is formed by synapse-to-nucleus communication that leads to regulation of gene transcription, but the identity and organizational logic of signaling pathways involved in this communication remain unclear. Here we find that the transcription cofactor CRTC1 is a critical determinant of sustained gene transcription and memory strength in the hippocampus. Following associative learning, synaptically localized CRTC1 is translocated to the nucleus and regulates Fgf1b transcription in an activity-dependent manner. After both weak and strong training, the HDAC3-N-CoR corepressor complex leaves the Fgf1b promoter and a complex involving the translocated CRTC1, phosphorylated CREB, and histone acetyltransferase CBP induces transient transcription. Strong training later substitutes KAT5 for CBP, a process that is dependent on CRTC1, but not on CREB phosphorylation. This in turn leads to long-lasting Fgf1b transcription and memory enhancement. Thus, memory strength relies on activity-dependent changes in chromatin and temporal regulation of gene transcription on specific CREB/CRTC1 gene targets. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  13. RELATIONSHIP BETWEEN ATTITUDES LEARNING AND ACHIEVEMENT OF INTEREST LEARNING WITH LEARNING THE BASICS OF COST OF DISCUSSION AUTOMOTIVE AUTOMOTIVE DEPARTMENT OF CLASS X SMK PIRI SLEMAN EVEN SEMESTER OF STUDY 2013/2014

    Directory of Open Access Journals (Sweden)

    Deril Gusa Wijaya

    2014-12-01

    Based on the analysis of the results obtained the following results: (1 There is a positive and significant relationship between the attitude of Learning (X1 with Achievement Automotive Basics (Y; (2 There is a positive and significant relationship between Interests Learning (X2 with Achievement Automotive Basics (Y; (3 There is a positive and significant relationship Attitude Study (X1 and Interest in Learning (X2 with Achievement Automotive Basics (Y.

  14. The learning conference

    DEFF Research Database (Denmark)

    Ravn, Ib

    little support amongst serious students of learning. The professional conference as a forum for knowledge sharing is in dire need of a new learning theory and a more enlightened practice. The notion of human flourishing is offered as basis for theory, and four simple design principles for the so......The typical one-day conference attended by managers or professionals in search of inspiration is packed with PowerPoint presentations and offers little opportunity for involvement or knowledge sharing. Behind the conventional conference format lurks the transfer model of learning, which finds......-called “learning conference” are proposed: People go to conferences to 1. get concise input, 2. interpret it in the light of their ongoing concerns, 3. talk about their current projects and 4. meet the other attendees and be inspired by them. Six practical techniques that induce attendees to do these things...

  15. Does peer learning or higher levels of e-learning improve learning abilities?

    DEFF Research Database (Denmark)

    Worm, Bjarne Skjødt; Jensen, Kenneth

    2013-01-01

    The fast development of e-learning and social forums demands us to update our understanding of e-learning and peer learning. We aimed to investigate if higher, pre-defined levels of e-learning or social interaction in web forums improved students' learning ability....

  16. Deep learning of unsteady laminar flow over a cylinder

    Science.gov (United States)

    Lee, Sangseung; You, Donghyun

    2017-11-01

    Unsteady flow over a circular cylinder is reconstructed using deep learning with a particular emphasis on elucidating the potential of learning the solution of the Navier-Stokes equations. A deep neural network (DNN) is employed for deep learning, while numerical simulations are conducted to produce training database. Instantaneous and mean flow fields which are reconstructed by deep learning are compared with the simulation results. Fourier transform of flow variables has been conducted to validate the ability of DNN to capture both amplitudes and frequencies of flow motions. Basis decomposition of learned flow is performed to understand the underlying mechanisms of learning flow through DNN. The present study suggests that a deep learning technique can be utilized for reconstruction and, potentially, for prediction of fluid flow instead of solving the Navier-Stokes equations. This work was supported by the National Research Foundation of Korea(NRF) Grant funded by the Korea government(Ministry of Science, ICT and Future Planning) (No. 2014R1A2A1A11049599, No. 2015R1A2A1A15056086, No. 2016R1E1A2A01939553).

  17. What students really learn: contrasting medical and nursing students' experiences of the clinical learning environment.

    Science.gov (United States)

    Liljedahl, Matilda; Boman, Lena Engqvist; Fält, Charlotte Porthén; Bolander Laksov, Klara

    2015-08-01

    This paper explores and contrasts undergraduate medical and nursing students' experiences of the clinical learning environment. Using a sociocultural perspective of learning and an interpretative approach, 15 in-depth interviews with medical and nursing students were analysed with content analysis. Students' experiences are described using a framework of 'before', 'during' and 'after' clinical placements. Three major themes emerged from the analysis, contrasting the medical and nursing students' experiences of the clinical learning environment: (1) expectations of the placement; (2) relationship with the supervisor; and (3) focus of learning. The findings offer an increased understanding of how medical and nursing students learn in the clinical setting; they also show that the clinical learning environment contributes to the socialisation process of students not only into their future profession, but also into their role as learners. Differences between the two professions should be taken into consideration when designing interprofessional learning activities. Also, the findings can be used as a tool for clinical supervisors in the reflection on how student learning in the clinical learning environment can be improved.

  18. Self-directed learning readiness and learning styles among Saudi undergraduate nursing students.

    Science.gov (United States)

    El-Gilany, Abdel-Hady; Abusaad, Fawzia El Sayed

    2013-09-01

    Self-directed learning has become a focus for nursing education in the past few decades due to the complexity and changes in nursing profession development. On the other hand, the Kolb's learning style could identify student's preference for perceiving and processing information. This study was performed to determine Saudi nursing students' readiness for self-directed learning; to identify their learning styles and to find out the relation between these two concepts. Cross-sectional descriptive study. Nursing department of faculty of Applied Medical Sciences, Al-Jouf University, Saudi Arabia. Two hundred and seventy-five undergraduate Saudi nursing students. Data was collected using self-administered questionnaires covering the demographic features of students, Fisher's self-directed learning readiness (SDLR) scale, and the Kolb's learning styles inventory. The mean scores of self-management, desire for learning, self-control and the overall SDLR were 51.3 ± 5.9, 48.4 ± 5.5, 59.9 ± 6.7, and 159.6 ± 13.8; respectively. About 77% (211) of students have high level of SDLR. The percentages of converger, diverger, assimilator and accommodator learning styles are 35.6%, 25.8%, 25.55% and 13.1%; respectively. The mean score of self-management, desire for learning, self-control and overall SDLR scale did not vary with any of the studied variables. There is no association between the level of SDLR and the learning styles. The high level of SDLR and the dominant converger learning style among undergraduate nursing students will have a positive implication for their education and post-employment continuing nursing education. Copyright © 2012 Elsevier Ltd. All rights reserved.

  19. Implementation of team-based learning in year 1 of a PBL based medical program: a pilot study.

    Science.gov (United States)

    Burgess, Annette; Ayton, Tom; Mellis, Craig

    2016-02-04

    A traditional and effective form of teaching within medical education has been Problem Based Learning (PBL). However, this method of teaching is resource intensive, normally requiring one tutor for every ten students. Team-based learning (TBL) has gained recent popularity in medical education, and can be applied to large groups of up to 100 students. TBL makes use of the advantages of small group teaching and learning, but in contrast to PBL, does not need large numbers of teachers. This study sought to explore the efficacy of using TBL in place of PBL in Year 1 of a medical program. In Year 1 of the medical program, two iterations of TBL, with 20 students, were run following four iterations of PBL within the Cardiology teaching block. Student feedback following PBL and TBL was collected by questionnaire, using closed and open ended questions. Additionally, individual and team tests were held at the beginning of each TBL class, and results of each week were compared. All students (n = 20) participated in the test in week 1, and 18/20 students participated in week 2. In total, 19/20 (95%) of students completed the questionnaires regarding their PBL and TBL experiences. The use of small groups, the readiness assurance tests, immediate feedback from an expert clinician, as well as time efficiency were all aspects of the TBL experience that students found positive. The clinical problem-solving activity, however, was considered to be less effective with TBL. There was a significant improvement (p = 0.004) in students' score from the week 1 assessment (median = 2) to the week 2 (median = 3.5) assessment. Interestingly, all teams but one (Team 1) achieved a lower score on their second week assessment than on their first. However, the lowest performing team in week 1 outperformed all other teams in week 2. Students favoured many aspects of the TBL process, particularly motivation to do the pre-reading, and better engagement in the process. Additionally, the

  20. Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice.

    Science.gov (United States)

    Basavarajappa, Balapal S; Nagre, Nagaraja N; Xie, Shan; Subbanna, Shivakumar

    2014-07-01

    In rodents, many exogenous and endogenous cannabinoids, such as anandamide (AEA) and 2-arachidonyl glycerol (2-AG), have been shown to play an important role in certain hippocampal memory processes. However, the mechanisms by which endogenous AEA regulate this processes are not well understood. Here the effects of AEA on long-term potentiation (LTP), hippocampal-dependent learning and memory tasks, pERK1/2, pCaMKIV, and pCREB signaling events in both cannabinoid receptor type 1 (CB1R) wild-type (WT) and knockout (KO) mice were assessed following administration of URB597, an inhibitor of the fatty acid amide hydrolase (FAAH). Acute administration of URB597 enhanced AEA levels without affecting the levels of 2-AG or CB1R in the hippocampus and neocortex as compared to vehicle. In hippocampal slices, URB597 impaired LTP in CB1R WT but not in KO littermates. URB597 impaired object recognition, spontaneous alternation and spatial memory in the Y-maze test in CB1R WT mice but not in KO mice. Furthermore, URB597 enhanced ERK phosphorylation in WT without affecting total ERK levels in WT or KO mice. URB597 impaired CaMKIV and CREB phosphorylation in WT but not in KO mice. CB1R KO mice have a lower pCaMKIV/CaMKIV ratio and higher pCREB/CREB ratio as compared to WT littermates. Our results indicate that pharmacologically elevated AEA impair LTP, learning and memory and inhibit CaMKIV and CREB phosphorylation, via the activation of CB1Rs. Collectively, these findings also suggest that pharmacological elevation of AEA beyond normal concentrations is also detrimental for the underlying physiological responses. © 2014 Wiley Periodicals, Inc.

  1. E-learning. A New Environment for Engagement

    DEFF Research Database (Denmark)

    Olesen, Mogens; K. Logan, Robert

    2012-01-01

    scaffold interactive learning and make it more engaging. The article analyzes e-learning, first by defining four aspects that are affected by it, and finally we sketch four levels of e-learning. On the basis of this analysis, we use a case topic (World War 2) to demonstrate how e-learning in practice can...... in their learning methods, i.e. e-learning. There are at least two strong arguments for e-learning: 1) it will help schools staying in tune with the rest of the society. 2) digital media offer opportunities to learn in new, activating ways. We use Andy Clark’s extended mind thesis to argue how technologies can...

  2. Identifying antigenicity-associated sites in highly pathogenic H5N1 influenza virus hemagglutinin by using sparse learning.

    OpenAIRE

    Cai, Zhipeng; Yang, Jialiang; Zhang, Tong; Long, Li-Ping; Boon, Adrianus C; Webby, Richard J; Wan, Xiu-Feng

    2012-01-01

    Since the isolation of A/goose/Guangdong/1/1996 (H5N1) in farmed geese in southern China, highly pathogenic H5N1 avian influenza viruses have posed a continuous threat to both public and animal health. The non-synonymous mutation of the H5 hemagglutinin (HA) gene has resulted in antigenic drift, leading to difficulties in both clinical diagnosis and vaccine strain selection. Characterizing H5N1's antigenic profiles would help resolve these problems. In this study, a novel sparse learning meth...

  3. Dynamic Learning Objects to Teach Java Programming Language

    Science.gov (United States)

    Narasimhamurthy, Uma; Al Shawkani, Khuloud

    2010-01-01

    This article describes a model for teaching Java Programming Language through Dynamic Learning Objects. The design of the learning objects was based on effective learning design principles to help students learn the complex topic of Java Programming. Visualization was also used to facilitate the learning of the concepts. (Contains 1 figure and 2…

  4. Ten Strengths of How Teachers Do Cooperative Learning

    Science.gov (United States)

    Jaocbs, George M.

    2016-01-01

    Cooperative learning involves students in working together with peers to learn, to develop learning skills and to enjoy the learning process. This paper examines ten areas in which the author believes he and other teachers do cooperative learning well. These areas are: (1) keeping group size small, usually four or fewer; (2) encouraging students…

  5. Interactive Radiological Anatomy eLearning Solution for First Year Medical Students: Development, Integration, and Impact on Learning

    Science.gov (United States)

    Webb, Alexandra Louise; Choi, Sunhea

    2014-01-01

    A technology enhanced learning and teaching (TELT) solution, radiological anatomy (RA) eLearning, composed of a range of identification-based and guided learning activities related to normal and pathological X-ray images, was devised for the Year 1 nervous and locomotor course at the Faculty of Medicine, University of Southampton. Its…

  6. Self-Determination, Engagement, and Identity in Learning German: Some Directions in the Psychology of Language Learning Motivation

    Science.gov (United States)

    Noels, Kimberly A.; Chaffee, Kathryn; Lou, Nigel Mantou; Dincer, Ali

    2016-01-01

    Drawing from Self-Determination Theory and diverse theories of language learning motivation, we present a framework that (1) represents a range of orientations that students may take towards learning German, and (2) explains how these orientations are connected to language learning engagement and diverse linguistic and non-linguistic outcomes. We…

  7. Theta coordinated error-driven learning in the hippocampus.

    Directory of Open Access Journals (Sweden)

    Nicholas Ketz

    Full Text Available The learning mechanism in the hippocampus has almost universally been assumed to be Hebbian in nature, where individual neurons in an engram join together with synaptic weight increases to support facilitated recall of memories later. However, it is also widely known that Hebbian learning mechanisms impose significant capacity constraints, and are generally less computationally powerful than learning mechanisms that take advantage of error signals. We show that the differential phase relationships of hippocampal subfields within the overall theta rhythm enable a powerful form of error-driven learning, which results in significantly greater capacity, as shown in computer simulations. In one phase of the theta cycle, the bidirectional connectivity between CA1 and entorhinal cortex can be trained in an error-driven fashion to learn to effectively encode the cortical inputs in a compact and sparse form over CA1. In a subsequent portion of the theta cycle, the system attempts to recall an existing memory, via the pathway from entorhinal cortex to CA3 and CA1. Finally the full theta cycle completes when a strong target encoding representation of the current input is imposed onto the CA1 via direct projections from entorhinal cortex. The difference between this target encoding and the attempted recall of the same representation on CA1 constitutes an error signal that can drive the learning of CA3 to CA1 synapses. This CA3 to CA1 pathway is critical for enabling full reinstatement of recalled hippocampal memories out in cortex. Taken together, these new learning dynamics enable a much more robust, high-capacity model of hippocampal learning than was available previously under the classical Hebbian model.

  8. Enhancing Students' Learning: Instant Feedback Cards

    Science.gov (United States)

    Mohrweis, Lawrence C.; Shinham, Kathe M.

    2015-01-01

    This study illustrates an active learning approach using instant feedback cards in the first course in accounting. The objectives of this study are to (1) describe instant feedback cards and (2) show how this tool, when used in an active learning environment, can enhance learning. We examined whether students exposed to immediate feedback…

  9. Learning, Learning Organisations and the Global Enterprise

    Science.gov (United States)

    Manikutty, Sankaran

    2009-01-01

    The steadily increasing degree of globalisation of enterprises implies development of many skills, among which the skills to learn are among the most important. Learning takes place at the individual level, but collective learning and organisational learning are also important. Learning styles of individuals are different and learning styles are…

  10. Homme kell 18 avatakse Tallinna Kunstihoones NIFKA näitus...

    Index Scriptorium Estoniae

    2006-01-01

    Kapitali mõistet uuriv rahvusvaheline grupinäitus "Kapital (see veab meid alt)". Kuraator Simon Sheikh, osalejad loetletud. Avaldatakse ka raamat, kus tutvustatakse Will Bradley, Katja Diefenbachi, Stephan Geene'i, Brian Holmes'i, Trude Iverseni, Oleg Kirejevi, Isabell Lorey, Gerald Rauningi ja Natascha Sadr Haghighiani loomingut ja esseesid

  11. Conférence de presse | Press Conference

    CERN Multimedia

    CERN. Geneva; Bejar Alonso, Isabel

    2018-01-01

    10:00-11:00 Conférence de presse en présence de Lucio Rossi, chef du projet LHC à Haute Luminosité et Isabel Bejar Alonso, chargée de la configuration, de la qualité et des ressources du projet LHC à Haute Luminosité.

  12. Notes on the ecology and status of some forest mammals in four ...

    African Journals Online (AJOL)

    Notes on the ecology and status of some forest mammals in four Eastern Arc Mountains, Tanzania. Norbert J Cordeiro, Nathalie Seddon, David R Capper, Jonathan MM Ekstrom, Kim M Howell, Isabel S Isherwood, Charles AM Msuya, Jonas T Mushi, Andrew W Perkin, Robert G Pople, William T Stanley ...

  13. Effects of Improving Primary Health Care Workers’ Knowledge About Public Health Services in Rural China: A Comparative Study of Blended Learning and Pure E-Learning

    Science.gov (United States)

    Zhan, Xingxin; Zhang, Zhixia; Sun, Fang; Liu, Qian; Peng, Weijun; Zhang, Heng

    2017-01-01

    Background Primary health care workers (PHCWs) are a major force in delivering basic public health services (BPHS) in rural China. It is necessary to take effective training approaches to improve PHCWs’ competency on BPHS. Both electronic learning (e-learning) and blended learning have been widely used in the health workers’ education. However, there is limited evidence on the effects of blended learning in comparison with pure e-learning. Objective The aim of this study was to evaluate the effects of a blended-learning approach for rural PHCWs in improving their knowledge about BPHS as well as training satisfaction in comparison with a pure e-learning approach. Methods The study was conducted among PHCWs in 6 rural counties of Hubei Province, China, between August 2013 and April 2014. Three counties were randomly allocated blended-learning courses (29 township centers or 612 PHCWs—the experimental group), and three counties were allocated pure e-learning courses (31 township centers or 625 PHCWs—the control group). Three course modules were administered for 5 weeks, with assessments at baseline and postcourse. Primary outcomes were score changes in courses’ knowledge. Secondary outcome was participant satisfaction (5-point Likert scale anchored between 1 [strongly agree] and 5 [strongly disagree]). Results The experimental group had higher mean scores than the control group in knowledge achievement in three course modules: (1) module 1: 93.21 (95% CI 92.49-93.93) in experimental group versus 88.29 (95% CI 87.19-89.40) in the control group; adjusted difference, 4.92 (95% CI 2.61-7.24; Plearning group gave more positive responses with the four issues than control group participants: (1) the increase of interest in learning, 1.85 (95% CI 1.22-2.80; P=.003); (2) the increase of interaction with others, 1.77 (95% CI 1.20-2.60; P=.004); (3) the satisfaction with learning experience, 1.78 (95% CI 1.11-2.88; P=.02); and (4) achievement of learning objectives, 1

  14. Cancer survival analysis using semi-supervised learning method based on Cox and AFT models with L1/2 regularization.

    Science.gov (United States)

    Liang, Yong; Chai, Hua; Liu, Xiao-Ying; Xu, Zong-Ben; Zhang, Hai; Leung, Kwong-Sak

    2016-03-01

    One of the most important objectives of the clinical cancer research is to diagnose cancer more accurately based on the patients' gene expression profiles. Both Cox proportional hazards model (Cox) and accelerated failure time model (AFT) have been widely adopted to the high risk and low risk classification or survival time prediction for the patients' clinical treatment. Nevertheless, two main dilemmas limit the accuracy of these prediction methods. One is that the small sample size and censored data remain a bottleneck for training robust and accurate Cox classification model. In addition to that, similar phenotype tumours and prognoses are actually completely different diseases at the genotype and molecular level. Thus, the utility of the AFT model for the survival time prediction is limited when such biological differences of the diseases have not been previously identified. To try to overcome these two main dilemmas, we proposed a novel semi-supervised learning method based on the Cox and AFT models to accurately predict the treatment risk and the survival time of the patients. Moreover, we adopted the efficient L1/2 regularization approach in the semi-supervised learning method to select the relevant genes, which are significantly associated with the disease. The results of the simulation experiments show that the semi-supervised learning model can significant improve the predictive performance of Cox and AFT models in survival analysis. The proposed procedures have been successfully applied to four real microarray gene expression and artificial evaluation datasets. The advantages of our proposed semi-supervised learning method include: 1) significantly increase the available training samples from censored data; 2) high capability for identifying the survival risk classes of patient in Cox model; 3) high predictive accuracy for patients' survival time in AFT model; 4) strong capability of the relevant biomarker selection. Consequently, our proposed semi

  15. How People Learn in an Asynchronous Online Learning Environment: The Relationships between Graduate Students' Learning Strategies and Learning Satisfaction

    Science.gov (United States)

    Choi, Beomkyu

    2016-01-01

    The purpose of this study was to examine the relationships between learners' learning strategies and learning satisfaction in an asynchronous online learning environment. In an attempt to shed some light on how people learn in an online learning environment, one hundred and sixteen graduate students who were taking online learning courses…

  16. Critical-Inquiry-Based-Learning: Model of Learning to Promote Critical Thinking Ability of Pre-service Teachers

    Science.gov (United States)

    Prayogi, S.; Yuanita, L.; Wasis

    2018-01-01

    This study aimed to develop Critical-Inquiry-Based-Learning (CIBL) learning model to promote critical thinking (CT) ability of preservice teachers. The CIBL learning model was developed by meeting the criteria of validity, practicality, and effectiveness. Validation of the model involves 4 expert validators through the mechanism of the focus group discussion (FGD). CIBL learning model declared valid to promote CT ability, with the validity level (Va) of 4.20 and reliability (r) of 90,1% (very reliable). The practicality of the model was evaluated when it was implemented that involving 17 of preservice teachers. The CIBL learning model had been declared practice, its measuring from learning feasibility (LF) with very good criteria (LF-score = 4.75). The effectiveness of the model was evaluated from the improvement CT ability after the implementation of the model. CT ability were evaluated using the scoring technique adapted from Ennis-Weir Critical Thinking Essay Test. The average score of CT ability on pretest is - 1.53 (uncritical criteria), whereas on posttest is 8.76 (critical criteria), with N-gain score of 0.76 (high criteria). Based on the results of this study, it can be concluded that developed CIBL learning model is feasible to promote CT ability of preservice teachers.

  17. Activating Student to Learn Chemistry using Chemmy Card 6-1 Game as an Instructional Medium in IUPAC Nomenclature of Inorganic Compounds

    Science.gov (United States)

    Lutfi, A.; Hidayah, R.

    2018-01-01

    The aim of this study is to know the effect of Internet-assisted Chemmy Card 6-1 game as an instructional medium in IUPAC Nomenclature of Inorganic Compounds material for X grade of senior high school on students’ activity, learning motivation, and learning outcome. The study was conducted at SMA Negeri Sidoarjo, Indonesia, in two different classes. The instruction was done based on the lesson plan made. The observation on students’ activity was conducted during the instruction with the game while test and questionnaire were given after the instruction. The result showed positive activities, which students listened to the teacher’s explanation, actively delivered questions, and enabled to solve problems in naming compounds. It was also effective to avoid the drowsiness. The result of students’ motivation of X MIPA 6 was 74.78% (good) while X MIPA 7 was 83.80% (very good). The pretest results of two classes showed that no students mastered but 100% students mastered and the increase of N-gain scores in two classes was categorized as high, ≥0,7, after the instruction. The result of this study showed that the use of Internet-assisted Chemmy Card 6-1 game in IUPAC nomenclature of inorganic compounds for X grade of senior high school could be pleasant for students to learn and effective in achieving the learning objective.

  18. Implicit sequence learning in people with Parkinson’s disease

    Directory of Open Access Journals (Sweden)

    Katherine R Gamble

    2014-08-01

    Full Text Available Implicit sequence learning involves learning about dependencies in sequences of events without intent to learn or awareness of what has been learned. Sequence learning is related to striatal dopamine levels, striatal activation, and integrity of white matter connections. People with Parkinson’s disease (PD have degeneration of dopamine-producing neurons, leading to dopamine deficiency and therefore striatal deficits, and they have difficulties with sequencing, including complex language comprehension and postural stability. Most research on implicit sequence learning in PD has used motor-based tasks. However, because PD presents with motor deficits, it is difficult to assess whether learning itself is impaired in these tasks. The present study used an implicit sequence learning task with a reduced motor component, the Triplets Learning Task (TLT. People with PD and age- and education-matched healthy older adults completed three sessions (each consisting of 10 blocks of 50 trials of the TLT. Results revealed that the PD group was able to learn the sequence, however, when learning was examined using a Half Blocks analysis (Nemeth et al., 2013, which compared learning in the 1st 25/50 trials of all blocks to that in the 2nd 25/50 trials, the PD group showed significantly less learning than Controls in the 2nd Half Blocks, but not in the 1st. Nemeth et al. hypothesized that the 1st Half Blocks involve recall and reactivation of the sequence learned, thus reflecting hippocampal-dependent learning, while the 2nd Half Blocks involve proceduralized behavior of learned sequences, reflecting striatal-based learning. The present results suggest that the PD group had intact hippocampal-dependent implicit sequence learning, but impaired striatal-dependent learning. Thus, sequencing deficits in PD are likely due to striatal impairments, but other brain systems, such as the hippocampus, may be able to partially compensate for striatal decline to improve

  19. Learning Theories In Instructional Multimedia For English Learning

    OpenAIRE

    Farani, Rizki

    2016-01-01

    Learning theory is the concept of human learning. This concept is one of the important components in instructional for learning, especially English learning. English subject becomes one of important subjects for students but learning English needs specific strategy since it is not our vernacular. Considering human learning process in English learning is expected to increase students' motivation to understand English better. Nowadays, the application of learning theories in English learning ha...

  20. Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice

    Science.gov (United States)

    Gajardo, Ivana; Salazar, Claudia S.; Lopez-Espíndola, Daniela; Estay, Carolina; Flores-Muñoz, Carolina; Elgueta, Claudio; Gonzalez-Jamett, Arlek M.; Martínez, Agustín D.; Muñoz, Pablo; Ardiles, Álvaro O.

    2018-01-01

    Long-term potentiation (LTP) and long-term depression (LTD) are two forms of synaptic plasticity that have been considered as the cellular substrate of memory formation. Although LTP has received considerable more attention, recent evidences indicate that LTD plays also important roles in the acquisition and storage of novel information in the brain. Pannexin 1 (Panx1) is a membrane protein that forms non-selective channels which have been shown to modulate the induction of hippocampal synaptic plasticity. Animals lacking Panx1 or blockade of Pannexin 1 channels precludes the induction of LTD and facilitates LTP. To evaluate if the absence of Panx1 also affects the acquisition of rapidly changing information we trained Panx1 knockout (KO) mice and wild type (WT) littermates in a visual and hidden version of the Morris water maze (MWM). We found that KO mice find the hidden platform similarly although slightly quicker than WT animals, nonetheless, when the hidden platform was located in the opposite quadrant (OQ) to the previous learned location, KO mice spent significantly more time in the previous quadrant than in the new location indicating that the absence of Panx1 affects the reversion of a previously acquired spatial memory. Consistently, we observed changes in the content of synaptic proteins critical to LTD, such as GluN2 subunits of N-methyl-D-aspartate receptors (NMDARs), which changed their contribution to synaptic plasticity in conditions of Panx1 ablation. Our findings give further support to the role of Panx1 channels on the modulation of synaptic plasticity induction, learning and memory processes. PMID:29692709