[Modeling of Processes of Migration and Accumulation of Radionuclides in Freshwater Ecosystems by the Example of the Samson, Lev, Vandras Rivers Related to the Ob-Irtysh River Basin].

Science.gov (United States)

Trapeznikov, A V; Korzhavin, A V; Trapeznikova, V N; Nikolkin, V N

2016-01-01

Mathematical models of horizontal distribution and migration of radionuclides are presented in water and floodplain soils of the Samson-Lev-Vandras river system related to the Ob-Irtysh river basin. Integral inventory of radionuclides in the main components of the river ecosystems is calculated. The estimated annual discharge of radionuclides from the Vandras river to the Great Salym river is given. The effect of the removal of man-made radionuclides in the Samson, Lev, Vandras rivers on radioactive contamination of the Ob-Irtysh river system is shown in comparison with the Techa river, that also belongs to the Ob-Irtysh river basin. Despite the presence of an additional radioactive contamination of the Samson floodplain, the transfer of radioactive substances in the Samson, Lev, Vandras rivers has a much smaller impact on the contamination of the Ob-Irtysh river system, compared to the Techa river, prone to a large-scale radioactive contamination.

[Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia. Hrsg. von Marek Tamm, Linda Kaljundi, Carsten Selch Jensen] / Volker Honemann

Index Scriptorium Estoniae

Honemann, Volker, 1943-

2013-01-01

Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia. Hrsg. von Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Verlag Ashgate. Farnham, 2011

Lev Landau and the concept of neutron stars

International Nuclear Information System (INIS)

Yakovlev, Dmitrii G; Haensel, Pawel; Baym, Gordon; Pethick, Christopher

2013-01-01

We review Lev Landau's role in the history of neutron star physics in the 1930s. According to the recollections of Rosenfeld (Proc. 16th Solvay Conference on Physics, 1974, p. 174), Landau improvised the concept of neutron stars in a discussion with Bohr and Rosenfeld just after the news of the discovery of the neutron reached Copenhagen in February 1932. We present arguments that the discussion must have taken place in March 1931, before the discovery of the neutron, and that they, in fact, discussed the paper written by Landau in Zurich in February 1931 but not published until February 1932 (Phys. Z. Sowjetunion 1, 285). In this paper, Landau mentioned the possible existence of dense stars that look like one giant nucleus; this could be regarded as an early theoretical prediction or anticipation of neutron stars, albeit prior to the discovery of the neutron. The coincidence of the dates of the neutron discovery and the publication of the paper has led to an erroneous association of Landau's paper with the discovery of the neutron. In passing, we outline Landau's contribution to the theory of white dwarfs and to the hypothesis of stars with neutron cores. (from the history of physics)

Lev Vygotsky between two revolutions: on the political self-determination of the scientist

Directory of Open Access Journals (Sweden)

Vladimir S. Sobkin

2016-09-01

Full Text Available The paper presented texts of the three previously unknown Lvygotsky’s journal notes and comments on them. These texts were published in mid-July and early September 1917 in the Jewish weekly «New Path» under the pseudonym «L.S.» and «W». In these texts, Lev Vygotsky describes the features of the political behaviour of the Jewish population in connection with the revolutionary events in Russia. On the one hand, a clear discrepancy between the activation of party work and political rhetoric is mentioned, and on the other hand, reduction of the significance of Jewish communal life is highlighted. As a key characteristic of social and psychological wellbeing of the Jewish population Vygotsky singles out absenteeism, i.e. the lack of interest in politics. Eventually the scientist captures the increase in uncertainty in the Jewish environment and fear of the future political, social and economic reforms in Russia. In the comments on Vygotsky notes, there are definitions relating to the various features of the activities of the Jewish political parties and public organizations, information about various policy documents and staff characterized by social and political situation before the elections in the Consituent Assembly (Uchreditel’noe Sobranie. Particular attention is paid to the analysis of stylistic and structural features of the commented text construction. By implicit quoting the relationship between Vygotsky’s texts and the works of other authors is identified. Particular attention is paid to the author’s attitude to religious texts, which allows to select a characteristic feature of the «double vision» of real events of the revolution against the background of the Jewish history. The comments help to single out features of the political identity of the young Lev Vygotsky in the period between the two revolutions, which is important to study his biography and understanding of his world view.

Œuvre 220 : Édouard Levé d’après Nicolas Brasseur - Entretien avec Olivier Sécardin

Directory of Open Access Journals (Sweden)

Olivier Sécardin

2017-06-01

Full Text Available Nicolas Brasseur, artiste, photographe, né en 1981 à Nantes. Vit et travaille à Paris. Diplômé de l’École Nationale Supérieure des Arts Décoratifs de Paris en 2008, Nicolas Brasseur poursuit un travail documentaire au sein d’institutions françaises autour de la notion « d’images modèles ». Ses recherches l’ont amené à photographier l’hôpital, l’école et plus récemment la prison en parte-nariat avec le Centre Photographique d’Ile-de-France (CPIF.Édouard Levé, écrivain, artiste, photographe, né en 1965, mort en 2007. Diplômé de l’ESSEC, il commence à peindre en 1991, puis brûle presque toutes ses toiles avant de se consacrer à la photographie. En 1999, il réalise sa première série, Homonymes, qui propose des portraits photographiques de personnes inconnues portant des noms célèbres : Georges Bataille, Yves Klein, Henri Michaux… Il reprend le même procédé dans Amérique (2006, reportage sur des villes américaines qui portent le nom d’autres villes connues : Florence, Berlin, Paris... Il est l’auteur de plusieurs séries photographiques. Admirateur de Raymond Roussel, lecteur de Jacques Roubaud et de Raymond Queneau, Édouard Levé est aussi écrivain. OEuvres, publié en 2002 est le catalogue de 533 projets d’oeuvres d’art, installations, peintures, sculptures ou photographies imaginés dont l’artiste a « eu l’idée, mais qu’il n’a pas réalisés ». Son Autoportrait le présente en « 1600 phrases sans solution de continuité ». Trois jours avant de se donner la mort, Édouard Levé dépose chez son éditeur le manuscrit de son dernier texte, Suicide (2008.

LA BASE AXIOLÓGICA DE LA EMPRESA CIENTÍFICA Y LA PLURALIDAD DE FINES EN LA CIENCIA EN LARRY LAUDAN

Directory of Open Access Journals (Sweden)

Marcos Antonio da Silva

2013-08-01

Full Text Available No presente artigo analiso as implicações das formulações teóricas de Larry Laudan com respeito à avaliação da ciência. Nele, o estudo dos valores epistêmicos, do método e dos fins da ciência, no contexto de seu naturalismo normativo, ganha sentido e o coloca como mais um instrumental importante na análise da atividade da ciência e de suas teorias. Daí resulta mais significativa sua proposta do modelo reticular, em seus três níveis de análise do conhecimento produzido pela ciência. O artigo mostra que este modelo constitui uma contribuição importante de Laudan para a Filosofia da Ciência.

Lev Vygotsky’s ideas in family group logopsychotherapy.

Directory of Open Access Journals (Sweden)

Karpova, N.L.

2014-09-01

Full Text Available According to Lev Vygotsky’s theory, every bodily deficiency not only changes a person’s attitude to the world but also entails social consequences, which makes its social and psychological rehabilitation so important. The way in which problems of deformity compensation and supercompensation are solved, is largely determined by a patient`s motivation. The paper deals with stuttering (logoneurosis as an extreme form of broken communication; it analyses the peculiarities of stutteres and their families, and the specific features of treating this defect; it also dwells on issues involving family co-participation in social rehabilitation. The multilayered system of family group logo psychotherapy - treatment of stuttering children, teenagers and adults - is based on Yu.B. Nekrasova’s method of group logopsychotherapy. It also employs non-traditional techniques: Nekrasova’s dynamic psycho-therapeutic diagnostics and biblio-, kinesi-, symbol-, video- and cinema therapies. This system may serve as a model for forming motivational involvement and intragenic activity by patients and their relatives in social rehabilitation processes. The paper describes the levels and psychological structure of motivational involvement and mechanisms of its formation in logopsychotherapeutic processes. Motivational involvement is understood as a source of a subject’s intragenic (inner activity, the paper maps out strategies to form intragenic activity. The family group logopsychotherapeutic techniques may also help optimize communication between parent and child, doctor and patient, teacher and pupil, professor and student.

The life, science and times of Lev Vasilevich Shubnikov pioneer of Soviet cryogenics

CERN Document Server

Reinders, L J

2018-01-01

This book describes the life, times and science of the Soviet physicist Lev Vasilevich Shubnikov (1901-1937).  From 1926 to 1930 Shubnikov worked in Leiden where he was the co-discoverer of the Shubnikov-De Haas effect. After his return to the Soviet Union he founded in Kharkov in Ukraine the first low-temperature laboratory in the Soviet Union, which in a very short time became the foremost physics institute in the country and among other things led to the discovery of type-II superconductivity. In August 1937 Shubnikov, together with many of his colleagues, was arrested and shot early in November 1937. This gripping story gives deep insights into the pioneering work of Soviet physicists before the Second World War, as well as providing much previously unpublished information about their brutal treatment at the hands of the Stalinist regime.

Evaluation of platelet aggregability during left ventricular bypass using a MedTech MagLev VAD in a series of chronic calf experiments.

Science.gov (United States)

Kimura, Taro; Yokoyama, Yoshimasa; Sakota, Daisuke; Nagaoka, Eiki; Kitao, Takashi; Takakuda, Kazuo; Takatani, Setsuo

2013-03-01

The impact of continuous flow left ventricular assist device (LVAD) pumping on platelet aggregation was investigated in animal experiments utilizing six calves. A single-use MagLev centrifugal blood pump, MedTech MagLev, was used to bypass the calves' hearts from the left atrium to the descending aorta at a flow rate of 50 ml/kg/min. The LVAD's impact on blood coagulation activities was evaluated based on the platelet aggregability, which was measured with a turbidimetric assay method during the preoperative, operative, and postoperative periods. Heparin and warfarin were used for anticoagulation, while aspirin was used for the antiplatelet therapy. A decrease in platelet aggregation immediately after the pump started was observed in the cases of successful long-term pump operation, while the absence of such a decrease might have caused coagulation-related complications to terminate the experiments. Thus, the platelet aggregability was found to be significantly affected by the pump, and its initial trend may be related to the long-term outcome of the mechanical circulatory support.

DISSOLUÇÃO DE FRONTEIRAS E A EXPERIÊNCIA TRANSICIONAL EM SOLAR STORMS, DE LINDA HOGAN

Directory of Open Access Journals (Sweden)

Caroline Garcia de Souza

2014-12-01

Full Text Available O presente trabalho analisa a experiência transicional no romance Solar Storms, publicado pela escritora nativo-americana Linda Hogan (Chickasaw em 1995. A obra narra a jornada de Angela, uma mestiça indígena órfã que retorna à terra de seus antepassados na tentativa de desvendar sua história e de religar os fragmentos de um passado parcialmente obscuro. Ao longo da narrativa, percebe-se um processo de gradual desconstrução de categorias – temporais, físicas, espaciais – e de superação das relações dicotômicas que opõem, por exemplo, indivíduo e comunidade, interioridade e exterioridade, o mundo humano e o não humano. Esse movimento se dá na direção de uma dissolução das falsas fronteiras e no sentido de uma integração total.

Integrating Cell Phone Imaging with Magnetic Levitation (i-LEV) for Label-Free Blood Analysis at the Point-of-Living.

Science.gov (United States)

Baday, Murat; Calamak, Semih; Durmus, Naside Gozde; Davis, Ronald W; Steinmetz, Lars M; Demirci, Utkan

2016-03-02

There is an emerging need for portable, robust, inexpensive, and easy-to-use disease diagnosis and prognosis monitoring platforms to share health information at the point-of-living, including clinical and home settings. Recent advances in digital health technologies have improved early diagnosis, drug treatment, and personalized medicine. Smartphones with high-resolution cameras and high data processing power enable intriguing biomedical applications when integrated with diagnostic devices. Further, these devices have immense potential to contribute to public health in resource-limited settings where there is a particular need for portable, rapid, label-free, easy-to-use, and affordable biomedical devices to diagnose and continuously monitor patients for precision medicine, especially those suffering from rare diseases, such as sickle cell anemia, thalassemia, and chronic fatigue syndrome. Here, a magnetic levitation-based diagnosis system is presented in which different cell types (i.e., white and red blood cells) are levitated in a magnetic gradient and separated due to their unique densities. Moreover, an easy-to-use, smartphone incorporated levitation system for cell analysis is introduced. Using our portable imaging magnetic levitation (i-LEV) system, it is shown that white and red blood cells can be identified and cell numbers can be quantified without using any labels. In addition, cells levitated in i-LEV can be distinguished at single-cell resolution, potentially enabling diagnosis and monitoring, as well as clinical and research applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Fatalizm logiczny i teologiczny a przedwiedza Boża. Krytyka argumentu antyredukcyjnego Lindy Zagzebski [ Fatalism logical and teological and God’s foreknowledge. Discussion with Linda Zagzebski’s anti-reductive argument

Directory of Open Access Journals (Sweden)

Dariusz Lukasiewicz

2014-06-01

Full Text Available The article presents arguments for theological and logical fatalism and analyzes the view that the theological fatalism can be reduced to or transformed into the logical one. Next, there follows a critique of Linda Zagzebski’s thesis that theological fatal- ism is not reducible to logical fatalism. The article begins with a brief presentation of the controversy between the proponents and opponents of the theological fatalism.

The Politics of Genre and Medium apropos of Frank O’Hara’s “On Seeing Larry Rivers’s Washington Crossing the Delaware (1955)

DEFF Research Database (Denmark)

Balle, Søren Hattesen

Frank O’Hara’s ekphrastic poem “On Seeing Larry Rivers’s Washington Crossing the Delaware” is only one work among others in a series of 1950s works in different genres and media relating to Emanuel Leutze’s romantic representation of the father of the American nation in his painting Washington...... event in American history. Inversely, only few critics take seriously the difference in both genre and medium between these different textual and graphic representations of Washington’s crossing and the questions such a difference may give rise to. In this paper I shall make an intergeneric......) and by narrativizing Rivers’s painting, the poem opens up alternative representational possibilities of the former and thus poses the question of whose ‘truth’ gets told or not told depending on the choice of genre and medium in representation. Thus, the intertextual relationship existing between Rivers’s painting...

The Animals Reader: The Essential Classic and Contemporary Writings (Linda Kalof y Amy Fitzgerald, Eds.

Directory of Open Access Journals (Sweden)

Beto Vianna

2009-01-01

Full Text Available Las propuestas explicativas de la sociobiología y, aún más recientemente, de la psicología evolucionista han suscitado la queja, entre los científicos humanos, de una “colonización de las ciencias sociales” (término de Rose, 2000 desde la biología. La queja es legítima, si no por otros motivos, por una lamentable tendencia a la simplificación de las intricadas redes conductuales humanas a través de “explicaciones evolutivas”. Pero no podemos olvidar que hay un movimiento de igual tamaño e impacto desde las ciencias sociales que, a ejemplo de Bruno Latour, Tim Ingold y tantos otros, “colonizan” los estudios y objetos naturales (ver, por ejemplo, Latour, 1996 e Ingold, 2008. En The Animals Reader, dos sociólogas - Linda Kalof, de la Universidad del Estado de Michigan, y Amy Fitzgerald, de la Universidade de Windsor, Canada - son las responsables de hacer una incursión en un territorio tradicionalmente natural y, por tanto, perteneciente a las ciencias de la naturaleza: las descripciones que hacemos y las relaciones que mantenemos con los animales. The Animals Reader es una compilación bien cuidada, pienso que la primera de su tipo, que da forma a una preocupación multidisciplinar: los “estudios animales”.

Cyclic steps and superimposed antidune deposits: important elements of coarse-grained deepwater channel-levée complexes

Science.gov (United States)

Lang, Joerg; Brandes, Christian; Winsemann, Jutta

2017-04-01

The facies distribution and architecture of submarine fans can be strongly impacted by erosion and deposition by supercritical density flows. We present field examples from the Sandino Forearc Basin (southern Central America), where cyclic-step and antidune deposits represent important sedimentary facies of coarse-grained channel-levée complexes. These bedforms occur in all sub-environments of the depositional systems and relate to the different stages of avulsion, bypass, levée construction and channel backfilling. Large-scale scours (18 to 29 m deep, 18 to 25 m wide, 60 to >120 m long) with an amalgamated infill, comprising massive, normally coarse-tail graded or spaced subhorizontally stratified conglomerates and pebbly sandstones, are interpreted as deposits of the hydraulic-jump zone of cyclic steps. These cyclic steps probably formed during avulsion, when high-density flows were routed into the evolving channel. The large-scale scour fills can be distinguished from small-scale channel fills based on the preservation of a steep upper margin and a coarse-grained infill comprising mainly amalgamated hydraulic-jump deposits. Channel fills include repetitive successions deposited by cyclic steps with superimposed antidunes. The hydraulic-jump zone of cyclic-step deposits comprises regularly spaced scours (0.2 to 2.6 m deep, 0.8 to 23 m wide), which are infilled by intraclast-rich conglomerates or pebbly sandstones and display normal coarse-tail grading or backsets. Laterally and vertically these deposits are associated with subhorizontally stratified, low-angle cross-stratified or sinusoidal stratified pebbly sandstones and sandstones (wavelength 0.5 to 18 m), interpreted as representing antidune deposits formed on the stoss-side of the cyclic steps during flow re-acceleration. The field examples indicate that so-called crudely or spaced stratified deposits may commonly represent antidune deposits with varying stratification styles controlled by the aggradation

Investigating the inter-relationship of Media Art and the Data Archive in the data-visualizations of Man Ray, Lev Manovich and Thorbjørn Lausten

DEFF Research Database (Denmark)

Søndergaard, Morten

This paper investigates the relationship of media art and the data archive. I propose that a complex situation of representation emerges between art and archive, which are operating in matrices of creativity rather than with semantic connections. From being a medium of memory (Benjamin), the data...... iterations/applications of) data-visualizations of Man Ray, Lev Manovich, Jacob Kierkegaard, Eric Andersen, and Thorbjørn Lausten this paper will argue that, what may be termed as, a creative 'matrix thinking' emerges....

Is Peace Journalism possible in the ‘war’ against terror in Somalia? How the Kenyan Daily Nation and the Standard represented Operation Linda Nchi

Directory of Open Access Journals (Sweden)

Fredrick Ogenga

2012-10-01

Full Text Available This paper concludes that in Africa the non-Western press may have the best chance to employ peace journalism, given its proximity to major conflicts. Nevertheless, the Kenyan press has so far failed to take advantage of an ideal opportunity for such an experiment in reporting on the war against terror. Kenya's press still operates within the war journalism framework. This paper employs a theoretical approach that combines theories of media representation in mainstream journalism with the concepts of peace journalism. Methodologically, it adopts a triangulating approach, employing both quantitative and qualitative content analysis to study the representations of Operation Linda Nchi by the Kenyan Daily Nation and The Standard and thereby offers a critical appraisal of the possibility for peace journalism to cover international terrorism in Africa.

Alexis de Tocqueville. Demokracie v Americe jako předobraz nové společnosti (s poukazem na recepci v českém myšlení – T. G. Masaryk, Lev Thun)

Czech Academy of Sciences Publication Activity Database

Svoboda, Jan

2015-01-01

Roč. 12, 3/4 (2015), s. 171-185 ISSN 1214-4967 Institutional support: RVO:67985955 Keywords : Alexis de Tocqueville * democracy in America * French Revolution * manners * equality * democratic despotism * new religion * T. G. Masaryk * Lev Thun Subject RIV: AA - Philosophy ; Religion

Multivariate Generalized Linear Mixed Models with High Complexity / Modèles linéaires généralisés mixtes multivariés avec complexité élevée

DEFF Research Database (Denmark)

Labouriau, Rodrigo

. À titre d'exemple, je présenterai quelques applications à la génétique quantitative avec complexité élevée (plusieurs centaines de milliers d'observations et des pedigrees profonds). Dans toutes les applications présentées, il est essentiel de comprendre le processus stochastique sous-jacent associé...

Les enrobés à module élevé : Bilan de l'expérience de française et transfert de technologie

OpenAIRE

BROSSEAUD, Y

2006-01-01

Les enrobés à module élevé (EME) sont devenus, après plus de 20 années d'expérience, une technique d'entretien, mais également de construction des routes, pleinement opérationnelle en France. Après avoir indiqué les évolutions des matériaux bitumineux pour assises de chaussées, quiu ont données naissance aux EME, les principes de formulation et les compositions types des EME sont présentées. L'article décrit les essais et les performance mécaniques imposées pour classer ces EME, conformément ...

Induction précoce de l'ovulation chez le saumon Atlantique Salmo salar élevé entièrement en eau douce

Directory of Open Access Journals (Sweden)

JALABERT B.

1980-10-01

Full Text Available Des essais réalisés sur une population de Saumon Atlantique de l'Allier, élevée entièrement en eau douce, ont démontré la possibilité d'induire artificiellement l'ovulation avec une avance d'au moins 15 jours sur la date d'ovulation naturelle. Le traitement le plus avantageux (dose minimale de gonadotropine de Saumon partiellement purifiée. G.S.P.P. de 0,1 mg/kg fournissant une réponse rapide est constitué par deux injections successives de G.S.P.P. (0,05 mg/kg suivies d'une injection de 17 x hydroxy-20 β dihydroprogestérone (2 mg/kg.

Food intake diet and sperm characteristics in a blue zone: a Loma Linda Study.

Science.gov (United States)

Orzylowska, Eliza M; Jacobson, John D; Bareh, Gihan M; Ko, Edmund Y; Corselli, Johannah U; Chan, Philip J

2016-08-01

The study examined the effect the life-long vegetarian diet on male fertility and focused on vegetarians living in the Loma Linda blue zone, a demographic area known for life longevity. The objective was to compare sperm characteristics of vegetarian with non-vegetarian males. The cross-sectional observational study was based on semen analyses of 474 males from 2009 to 2013. Patients categorized themselves as either life-long lacto-ovo vegetarians (N=26; vegetable diet with dairy and egg products), vegans (N=5; strictly vegetables with no animal products) or non-vegetarians (N=443; no diet restrictions). Sperm quality was assessed using a computer-aided sperm analyzer and strict morphology and chromatin integrity were manually evaluated. Lacto-ovo vegetarians had lower sperm concentration (50.7±7.4M/mL versus non-vegetarians 69.6±3.2M/mL, mean±S.E.M.). Total motility was lower in the lacto-ovo and vegan groups (33.2±3.8% and 51.8±13.4% respectively) versus non-vegetarians (58.2±1.0%). Vegans had lowest hyperactive motility (0.8±0.7% versus lacto-ovo 5.2±1.2 and non-vegetarians 4.8±0.3%). Sperm strict morphologies were similar for the 3 groups. There were no differences in rapid progression and chromatin integrity. The study showed that the vegetables-based food intake decreased sperm quality. In particular, a reduction in sperm quality in male factor patients would be clinically significant and would require review. Furthermore, inadequate sperm hyperactivation in vegans suggested compromised membrane calcium selective channels. However, the study results are cautiously interpreted and more corroborative studies are needed. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

[Julija Z. Kantor. Pribaltika. Vojna bez pravil (1939-1945) Sankt-Peterburg, 2011 ; Lev F. Sockov. Pribaltika i geopolitika 1935-1945 gg. Rassekreennye dokumenty Služby vnešnej razvedki Rossiskoj Federacii. Moskva, 2009 ; Anatolij A. Sazonov. "Sove

Index Scriptorium Estoniae

Makhotina, Ekaterina, 1982-

2014-01-01

Arvustus: Julija Z. Kantor. Pribaltika. Vojna bez pravil (1939-1945) Sankt-Peterburg, 2011 ; Lev F. Sockov. Pribaltika i geopolitika 1935-1945 gg. Rassekreennye dokumenty Služby vnešnej razvedki Rossiskoj Federacii. Moskva, 2009 ; Anatolij A. Sazonov. "Sovetskaja okkupacija" Pribaltiki v archivnych dokumentach. Projekt "Argumenty istiny". Moskva, 2009

THE DEVELOPMENT OF LEV VLADIMIROV’S PROFESSIONAL AND SCIENTIFIC INTERESTS

Directory of Open Access Journals (Sweden)

Akstinaite, Egle

2006-12-01

Full Text Available Lev Vladimirov (1912–1999 is one of the most famous and most prolific representatives of librarianship, bibliology and information sciences, the founder of the before mentioned spheres in Lithuania. The article focuses on the development of L. Vladimirov’s multidimensional interests, the priorities and interelations, mainly focusing on his works in book science. Biographical research helps reveal the circumstances that influenced L. Vladimirov’s work and attidude, as well as helps name the fundamental stages of his work. Much attention is paid to his family as one of the crucial elements that developed his personality and social skills. The prevailing values in the family predetermined the scholar’s social, political attitudes and models of behaviour. L. Vladimirov’s biography is analysed since the very childhood in the bookish people family, the questions of origin and identity are raised, the importance of education in interwar Lithuania in Siauliai German Progymnasium (1923–1928, in Silute Herder’s Real Gymnasium (1928–1932 and studies inKaunas Vytautas Magnum and Vilnius Universities (1932–1940 are assessed. The stages of scientific and professional work are discussed – starting from the beginning to work at Vilnius University in 1948, L. Vladimirov, while supervising the library of the university, trained and educated specialists and staff of librarianship. The job in Vilnius University and its library was a possibility for L. Vladimirov to start works in librarianship, take interest in ancient books, Lithuanian culture, its heritage and place in the world context. In 1964–1970 L. Vladimirov lead Dag HammarskjöldLibrary of United Nations in New York, took part in International Federation of Library Associations (IFLA works. While working in the library he had an opportunity to apply to the sources of book origin that were hardly available in Lithuania. New experience inspired new directions in scientific researches �

Una finestra su una dimensione "altra": sguardi e riflessi nel Progetto Wuppertal di Lev Kopelev

Directory of Open Access Journals (Sweden)

Giulia Peroni

2015-01-01

Full Text Available Lev Kopelev grew up and studied during Stalinism, when a progressive closure towards the West characterized Eastern countries. Nevertheless, thanks to different inputs he received as a young man, he underwent a path of personal growth, which led him to develop a project of dialogue and openness towards the “other”. Surrounded by the cosmopolitan atmosphere of Kiev at the beginning of the XX century, he learned German as child, and kept researching an open dialogue with the German people, which reached his peak in the Eighties, after he was deprived of the Soviet citizenship and became a citizen of the Federal Republic of Germany. Germanist by profession, he dedicated his life to the in depth examination of the links between Russians and Germans towards the centuries, and got to formulate the theory of a spiritual “elective affinity” between the two nations. His research led to a great project: the “Wuppertaler Projekt zur Erforschung der Geschichte Deutsch-Russischer Fremdenbilder”. In this work Kopelev firstly analysed the evolution of the relationship between the two nations from a literary, political, social and cultural point of view, and, secondly, examined the genesis and the development of the prejudices of the Germans towards the Russians and vice versa. The work showed the intrinsic groundlessness of these prejudices and offered the two nations the possibility of observing and understanding a different reality.

Tradurre per comprendere: colpa, pentimento e rinascita in “Semejnoe sčast’e” di Lev Tolstoj e nella traduzione italiana di Clemente Rebora

Directory of Open Access Journals (Sweden)

Anna Bonola

2014-01-01

Full Text Available This essay deals with the issue of guilt, repentance and rebirth in the short novel Semejnoe sčast’e (Family Happiness by Lev N. Tolstoy (1859. The author first considers the concepts of ‘offense’ , ‘repentance’ and ‘forgiveness’ through an analysis of the Russian terminology used by Tolstoy for these semantic fields (obida, dosada, vina, raskajanie, pokajanie; next, in an analysis of Clemente Rebora’s Italian translation (1920, special attention is paid to the differences from the original text that signal the translator’s interpretive reading, which, at the same time, becomes a tool for understanding it. It is shown how, in the transition from Russian into Italian, semantic shifts and phonetic symbolism add a mystical tension to the original Tolstoyan text which is typical of the poetry of Clemente Rebora.

2005 40th Annual Armament Systems: Guns - Ammunition - Rockets - Missiles Conference and Exhibition. Volume 2: Wednesday

Science.gov (United States)

2005-04-28

PM] Abraham Overview, Mr. Robert Daunfeldt, Bofors Defence Summary Overview of an Advanced 2.75 Hypervelocity Weapon, Mr. Larry Bradford , CAT Flight...Substantially Improves 2.75 Rocket Lethality, Safety, Survivability Mr. Larry Bradford , CAT Flight Services, Inc. APKWS Flight Test Results Mr. Larry S...Company Lead: Larry Bradford Atlantic Research Propellant Mixing/Loading, Nozzle Manufacturing, Corporation Motor Static Testing Company Lead: Steve

40th Annual Armament Systems: Guns-Ammunition-Rockets-Missiles Conference and Exhibition

Science.gov (United States)

2005-04-28

PM] Abraham Overview, Mr. Robert Daunfeldt, Bofors Defence Summary Overview of an Advanced 2.75 Hypervelocity Weapon, Mr. Larry Bradford , CAT Flight...Substantially Improves 2.75 Rocket Lethality, Safety, Survivability Mr. Larry Bradford , CAT Flight Services, Inc. APKWS Flight Test Results Mr. Larry S

2005 40th Annual Armament Systems Guns - Ammunition - Rockets - Missiles Conference and Exhibition. Volume 1: Tuesday

Science.gov (United States)

2005-04-28

PM] Abraham Overview, Mr. Robert Daunfeldt, Bofors Defence Summary Overview of an Advanced 2.75 Hypervelocity Weapon, Mr. Larry Bradford , CAT Flight...Substantially Improves 2.75 Rocket Lethality, Safety, Survivability Mr. Larry Bradford , CAT Flight Services, Inc. APKWS Flight Test Results Mr. Larry S

2005 40th Annual Armament Systems: Guns - Ammunition - Rockets - Missiles Conference and Exhibition. Volume 3: Wednesday

Science.gov (United States)

2005-04-28

PM] Abraham Overview, Mr. Robert Daunfeldt, Bofors Defence Summary Overview of an Advanced 2.75 Hypervelocity Weapon, Mr. Larry Bradford , CAT Flight...Substantially Improves 2.75 Rocket Lethality, Safety, Survivability Mr. Larry Bradford , CAT Flight Services, Inc. APKWS Flight Test Results Mr. Larry S

Draft Environmental Impact Statement for Divert Activities and Exercises, Guam and Commonwealth of the Northern Mariana Islands

Science.gov (United States)

2012-06-01

and other wildlife from suitable habitat in the 7 proposed Project Area. Smaller, less-mobile species and those seeking refuge in burrows could 8...the NONROAD model and were provided to e²M by Larry Landman of the Air Quality and Modeling Center (Landman.Larry@epamail.epa.gov) on 12/14/07...Emission factors are taken from the NONROAD model and were provided to e²M by Larry Landman of the Air Quality and Modeling Center (Landman.Larry

77 FR 64967 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2012-10-24

... BROWN, STEPHANIE H BRYAN, WILLIAM N BURROWS, CHARLES W BUTTRESS, LARRY D CADIEUX, GENA E CALBOS, PHILIP..., CAROL J BEAMON, JOSEPH A BEARD, JEANNE M BEARD, SUSAN F BEAUSOLEIL, GEOFFREY L BEKKEDAHL, LARRY N BELL..., HENRY C KELLY, JOHN E KELLY, LARRY C KENCHINGTON, HENRY S KENDELL, JAMES M KETCHAM, TIMOTHY E KHAN...

78 FR 70027 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2013-11-22

..., WILLIAM N. BURROWS, CHARLES W. BUTTRESS, LARRY D. CADIEUX, GENA E. CALBOS, PHILIP T. CALLAHAN, SAMUEL N..., LARRY N. BELL, MELODY C. BESTANI, ROBERT M. BIENIAWSKI, ANDREW J. BIERBOWER, WILLIAM J. BINKLEY, JOHN S..., STAN M. KEARNEY, JAMES H. KELLY, HENRY C. KELLY, JOHN E. KELLY, LARRY C. KENCHINGTON, HENRY S. KENDELL...

Erosion and deposition by supercritical density flows during channel avulsion and backfilling: Field examples from coarse-grained deepwater channel-levée complexes (Sandino Forearc Basin, southern Central America)

Science.gov (United States)

Lang, Jörg; Brandes, Christian; Winsemann, Jutta

2017-03-01

Erosion and deposition by supercritical density flows can strongly impact the facies distribution and architecture of submarine fans. Field examples from coarse-grained channel-levée complexes from the Sandino Forearc Basin (southern Central America) show that cyclic-step and antidune deposits represent common sedimentary facies of these depositional systems and relate to the different stages of avulsion, bypass, levée construction and channel backfilling. During channel avulsion, large-scale scour-fill complexes (18 to 29 m deep, 18 to 25 m wide, 60 to > 120 m long) were incised by supercritical density flows. The multi-storey infill of the large-scale scour-fill complexes comprises amalgamated massive, normally coarse-tail graded or widely spaced subhorizontally stratified conglomerates and pebbly sandstones, interpreted as deposits of the hydraulic-jump zone of cyclic steps. The large-scale scour-fill complexes can be distinguished from small-scale channel fills based on the preservation of a steep upper margin and a coarse-grained infill comprising mainly amalgamated hydraulic-jump zone deposits. Channel fills include repeated successions deposited by cyclic steps with superimposed antidunes. The deposits of the hydraulic-jump zone of cyclic steps comprise regularly spaced scours (0.2 to 2.6 m deep, 0.8 to 23 m long) infilled by intraclast-rich conglomerates or pebbly sandstones, displaying normal coarse-tail grading or backsets. These deposits are laterally and vertically associated with subhorizontally stratified, low-angle cross-stratified or sinusoidally stratified sandstones and pebbly sandstones, which were deposited by antidunes on the stoss side of the cyclic steps during flow re-acceleration. The field examples indicate that so-called spaced stratified deposits may commonly represent antidune deposits with varying stratification styles controlled by the aggradation rate, grain-size distribution and amalgamation. The deposits of small-scale cyclic

Bupivacaína levógira a 0,5% pura versus mistura enantiomérica de bupivacaína (S75-R25 a 0,5% em anestesia peridural para cirurgia de varizes Bupivacaína levógira a 0,5% pura versus mezcla enantiomerica bupivacaína (S75-R25 a 0,5% en anestesia peridural para cirugía de várices Plain 0.5% levogyrous bupivacaine versus 0.5% bupivacaine enantiomeric mixture (S75-R25 in epidural anesthesia for varicose vein surgery

Directory of Open Access Journals (Sweden)

José Delfino

2001-12-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A cardiotoxicidade da bupivacaína racêmica (50:50 ainda é a grande variável relacionada à segurança de indicação nos bloqueios regionais que exigem massas e volumes elevados. Recentes experimentações em animais sugerem que a modificação da relação enantiomérica da bupivacaína racêmica poderia contribuir para sua eficácia terapêutica e diminuição de sua toxicidade potencial. O objetivo do presente estudo foi comparar a eficiência da mistura enantiomérica de bupivacaína (S75-R25 com a levógira pura S(-100 na anestesia peridural lombar para cirurgias de varizes dos membros inferiores. MÉTODO: O estudo envolveu 30 pacientes do sexo feminino com idades entre 15 e 65 anos, estado físico ASA I ou II, programados para cirurgia eletiva de varizes. Em teste aleatório e duplamente encoberto, os pacientes foram divididos em dois grupos de 15: Grupo S75-R25 - 20 ml (100 mg de mistura enantiomérica de bupivacaína a 0,5% (S75-R25 - e Grupo Levógiro - 20 ml (100 mg de bupivacaína levógira S(-100% a 0,5% sem adjuvante. Foram comparadas as características dos bloqueios sensitivo e motor bem como a incidência de efeitos colaterais. RESULTADOS: Foram detectadas diferenças intergrupais relacionadas às características demográficas e um maior tempo cirúrgico no grupo S75-R25. A dispersão mais rápida e a menor potência analgésica da mistura isomérica exibiram significância estatística. Não houve diferença significativa relacionada à ocorrência de efeitos colaterais. O grupo levógiro apresentou menor relaxamento muscular. CONCLUSÕES: A redução da incidência de efeitos colaterais, a receptividade do método pelos pacientes, a ausência de sintomatologia neurológica transitória pós-operatória apontam para a aplicação segura de ambas as soluções em anestesia peridural lombar para cirurgia de varizes dos membros inferiores. A casuística, entretanto, não é ainda suficiente para

Environmental Assessment for Ecosystem Restoration Masterplan Implementation at MacDill Air Force Base, Florida

Science.gov (United States)

2013-05-01

SSC Burrowing owl Athene cunicularia - SSC Piping plover Charadrius melodus T T Southeastern snowy plover Charadrius alexandrinus...Department of Environmental Protection 3900 Commonwealth Blvd, M.S. 47 Tallahassee, FL 32399-3000 Commissioner Larry Bustle Chair Mayor Robert Minning...the NONROAD model and were provided to e²M by Larry Landman of the Air Quality and Modeling Center (Landman.Larry@epamail.epa.gov) on 12/14/07

A review of vagus nerve stimulation as a therapeutic intervention

OpenAIRE

Johnson RL; Wilson CG

2018-01-01

Rhaya L Johnson,1 Christopher G Wilson1,2 1Lawrence D Longo MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA; 2Department of Pediatrics, Loma Linda University, Loma Linda, CA, USA Abstract: In this review, we provide an overview of the US Food and Drug Administration (FDA)-approved clinical uses of vagus nerve stimulation (VNS) as well as information about the ongoing studies and preclinical research to expand the use of VNS to addition...

Intrauterine devices (IUD)

Science.gov (United States)

... Professor of Obstetrics and Gynecology, Loma Linda University School of Medicine, Loma Linda Center for Fertility, Loma Linda, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Birth Control Read more NIH MedlinePlus Magazine Read more Health ...

Tagasivaade veebruarikuu tegevusele Ehatares / Linda Püssa ; fotod: Linda Püssa

Index Scriptorium Estoniae

Püssa, Linda

2009-01-01

tegevusjuhi Rosemarie Lindau sünnipäevast, sõbrapäevast, EV aastapäeva tähistamisest Ehatare kirikusaalis ja Vana-Andrese kirikus, Inna ja Aadu Randpalule Eesti Punase Risti III klassi teenetemärgi andmisest

An Interview with Larry Fink

Directory of Open Access Journals (Sweden)

Didier Aubert

2011-04-01

Full Text Available 1. Do you happen to remember the first time you actually made money with a picture you took?You have to go back to 1961. Before that I was trying to pick up work here and there as an assistant but I couldn’t because I was an undisciplined bum, so people would fire me. Then I studied with Lisette Model. My parents were very nice to me. They allowed me to float around as an artist. I didn’t really have to suffer or suffocate myself by driving a cab or anything like that. So I was very fortunate...

El desarrollo de la competencia intercultural en el contexto cubano: estrategias para la superación de estereotipos en la clase de E/LE a través de la propuesta didáctica «¡Cuba, qué linda es Cuba!»

Directory of Open Access Journals (Sweden)

Tania Abella Fernández

2015-10-01

Full Text Available La propuesta didáctica «¡Cuba, qué linda es Cuba!» está dirigida a grupos multiculturales de E/LE (Español como lengua extranjera con nivel A2 en el contexto cubano. Surge a partir de la experiencia directa con estos grupos los cuales presentaban problemas de identificación intercultural durante el proceso de enseñanza-aprendizaje. Se supuso que esto era un obstáculo para el desarrollo de las competencias generales y lingüísticas de los estudiantes. Por tanto, se persigue como objetivo activar determinadas estrategias de aprendizaje para propiciar un mayor acercamiento entre estos aprendientes que favorezca el desarrollo de su competencia intercultural y comunicativa. Para ello se proponen actividades concebidas desde un enfoque comunicativo e intercultural.

Posjolok / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2006-01-01

Tallinna Marta, Magdaleena ja Asula tänavate hoonestusajaloost. Ajaloolistest sündmustest, mida on meenutamas kõrge paekivirist Marta tänava ääres. Mälestusmärk püstitati 1560. a. Liivi sõjas langenud Tallinna raehärra Blasius Hochgrave mälestuseks. Selles lahingus hukkunud mustpeade mälestuseks maalitud Kiek in de Kökis asuvast pilt-epitaafist. Epitaafi autor on Lambert Glandorf

10 noort veebifirmat, millel tasub silm peal hoida

Index Scriptorium Estoniae

2008-01-01

Aastatel 2003-2008 asutatud ettevõtetest Ushahidi, Mashery, 33Across, Qik, Pinger, QTech, Dash Navigation, Powence, Anagran ning Peer39, mis loodavad kasu teenida innovaatiliste sotsiaalse interneti ideedega. Vt. samas: David Talbot. Kriisiallikate kaardistamine; Lissa Harris. Erinevate veebilehtede andmete integreerimine on nüüd lihtne; Larry Aragon. Kas sul on... mõjuvõimu?; David Talbot. Videoedastus mobiiltelefoniga; Larry Aragon. Kiire kõnepostiteenus; Lissa Harris. Kõik ei lähegi meelest ära!; David Talbot. Liiklusekspert; Lissa Harris. Privaatne failivahetus; Larry Aragon. Videopakettide edastus; Lissa Harris. Semantilised reklaamid

Lev Shestov as a Theologian and the Theology of the Great and Ultimate Battle

Directory of Open Access Journals (Sweden)

Natalya Bonetskaya

2015-04-01

Full Text Available Lev Shestov’s early period in which he developed his religious views is the subject of this article. Shestov was a well-known Russian thinker. The author sheds some light on the furtive character of his thought as well as attempts to reconstruct the sources of his religious consciousness. He was formed at the border between two religious worlds — that of Judaism and that of Christianity. Traces of Jewish free-thinking typical of the end of the nineteenth century color his Weltanschauung together with the infl uence of Nietzsche and the Bible, the last as it was interpreted by the western tradition. Shestov understands God in a way akin to that of anthropomorphic psychology, an understanding which develops the concept of the deity into a form of radical apophatic ignorance or the complete absence of the ability to know God. The author points out that Shestov’s God is not the God of life and religious experience but rather a product of a kind of radicalized rationality. This notwithstanding, the original theological perceptions of Shestov were generated by his search for an authentic philosophical life. The author concentrates her attention on two main tendencies in Shestov’s understanding of life — a holistic tendency and a personalistic tendency. From a reading of Shestov’s first book (Shakespeare and his critic Brandes published in 1898 it becomes clear that the personalistic tendency won out. The concept of rebellion takes first place in Shestov’s thought as well as that of the great and ultimate battle. As a result Shestov’s thought becomes dominated by anthopology rather than theology and the concept of God gives way to that of man as the rebel. Shestov’s thought, particularly in his works dating from the second half of the twentieth century, falls under the influence of Nietzsche and the man from the underground of Dostoevsky. His God becomes the God of Manichaeism, on the far side of neither good nor evil, and his

Transformation of miniature potted rose (Rosa hybrida cv. Linda) with P( SAG12 )-ipt gene delays leaf senescence and enhances resistance to exogenous ethylene.

Science.gov (United States)

Zakizadeh, Hedayat; Lütken, Henrik; Sriskandarajah, Sridevy; Serek, Margrethe; Müller, Renate

2013-02-01

KEY MESSAGE : The P ( SAG12 ) -ipt gene was transferred to miniature rose, as the first woody species, resulting in increased ethylene resistance due to specific up-regulation of the ipt gene under senescence promoting conditions. Transgenic plants of Rosa hybrida 'Linda' were obtained via transformation with Agrobacterium tumefaciens strain harboring the binary vector pSG529(+) containing the P( SAG12 )-ipt construct. A. tumefaciens strains AGL1, GV3850 and LBA4404 (containing P(35S)-INTGUS gene) were used for transformation of embryogenic callus, but transgenic shoots were obtained only when AGL1 was applied. The highest transformation frequency was 10 % and it was achieved when half MS medium was used for the dilution of overnight culture of Agrobacterium. Southern blot confirmed integration of 1-6 copies of the nptII gene into the rose genome in the tested lines. Four transgenic lines were obtained which were morphologically true-to-type and indistinguishable from Wt shoots while they were in in vitro cultures. Adventitious root induction was more difficult in transgenic shoots compared to the Wt shoots, however, one of the transgenic lines (line 6) was rooted and subsequently analyzed phenotypically. The ipt expression levels were determined in this line after exposure to exogenous ethylene (3.5 μl l(-1)) and/or darkness. Darkness resulted in twofold up-regulation of ipt expression, whereas darkness combined with ethylene caused eightfold up-regulation in line 6 compared to Wt plants. The transgenic line had significantly higher content of chlorophyll at the end of the treatment period compared to Wt plants.

Ifp's New Flexible Hydrocracking Process Combines Maximum Conversion with Production of High Viscosity, High Vi Lube Stocks Le nouveau procédé IFP d'hydrocraquage à haute flexibilité combine conversion maximum et production de bases, huile à haute viscosité et à indice de viscosité élevé

Directory of Open Access Journals (Sweden)

Hennico A.

2006-11-01

Full Text Available Institut Français du Pétrole (IFP has developed a new dual catalytic system for its hydrocracking process that enables high conversion to middle distillates and production of high viscosity, high VI lube stocks. Although the hydrocracking process is mainly devoted to the conversion of vacuum distillates, deasphalted oil or mixture of both into high quality middle distillates, it can also produce a residue, that after dewaxing will be a very high VI lube base oil. In this presentation major emphasis is put on the possibility to produce very high VI lubes with high viscosity thanks to the development of the new catalytic system. Large flexibility in feedstock selection and easy control of operating variables allow the production of all grades of lube oils associated with high quality middle distillates for a large range of conversion levels. L'Institut Français du Pétrole (IFP a mis au point, pour son procédé d'hydrocraquage, un nouveau système catalytique à 2 catalyseurs qui permet une forte conversion en distillats moyens et la production de fractions lubrifiantes à haute viscosité et indice de viscosité élevé. Si le procédé d'hydrocraquage est essentiellement utilisé pour la conversion de distillats sous vide, d'huile désasphaltée ou d'un mélange des deux en distillats moyens de haute qualité, il peut aussi produire un résidu qui, après déparaffinage, fournira une base pour lubrifiant à indice de viscosité très élevé. Cet article souligne particulièrement la possibilité de produire des lubrifiants à indice de viscosité très élevé et haute viscosité, grâce à ce nouveau système catalytique. Une grande flexibilité dans le choix des produits à traiter et la facilité de contrôle des paramètres opératoires permet la production de toutes les qualités d'huiles lubrifiantes associées à des distillats moyens de haute qualité, pour une large gamme de niveaux de conversion.

Origin, Physical, and Mineralogical Nature of Red Clays: The Pacific Ocean Basin as a Model. (Geo-Marine Letters, An International Journal of Marine Geology. Volume 8, Number 4, 1988)

Science.gov (United States)

1988-01-01

California, USA Alberto G. de Flgueiredo Lab. Geologia Marinha. Universidude Federal Fluminense. Niteroi. Brazil Larry J. Doyle University of South...USA Alberto G. de Flguelredo Lab. Geologia Marinha, Universidude Federal Fluminense, Niteroi, Brazil Larry J. Doyle University of South Florida

Parallel computation for biological sequence comparison: comparing a portable model to the native model for the Intel Hypercube.

Science.gov (United States)

Nadkarni, P M; Miller, P L

1991-01-01

A parallel program for inter-database sequence comparison was developed on the Intel Hypercube using two models of parallel programming. One version was built using machine-specific Hypercube parallel programming commands. The other version was built using Linda, a machine-independent parallel programming language. The two versions of the program provide a case study comparing these two approaches to parallelization in an important biological application area. Benchmark tests with both programs gave comparable results with a small number of processors. As the number of processors was increased, the Linda version was somewhat less efficient. The Linda version was also run without change on Network Linda, a virtual parallel machine running on a network of desktop workstations.

Underrepresented minority high school and college students report STEM-pipeline sustaining gains after participating in the Loma Linda University Summer Health Disparities Research Program.

Directory of Open Access Journals (Sweden)

Lorena M Salto

Full Text Available An urgent need exists for graduate and professional schools to establish evidence-based STEM (science, technology, engineering, and math pipeline programs to increase the diversity of the biomedical workforce. An untapped yet promising pool of willing participants are capable high school students that have a strong STEM interest but may lack the skills and the guided mentoring needed to succeed in competitive STEM fields. This study evaluates and compares the impact of the Loma Linda University (LLU Summer Health Disparities Research Program on high school (HS and undergraduate (UG student participants. The primary focus of our summer research experience (SRE is to enhance the research self-efficacy of the participants by actively involving them in a research project and by providing the students with personalized mentoring and targeted career development activities, including education on health disparities. The results of our study show that our SRE influenced terminal degree intent and increased participant willingness to incorporate research into future careers for both the HS and the UG groups. The quantitative data shows that both the HS and the UG participants reported large, statistically significant gains in self-assessed research skills and research self-efficacy. Both participant groups identified the hands-on research and the mentor experience as the most valuable aspects of our SRE and reported increased science skills, increased confidence in science ability and increased motivation and affirmation to pursue a science career. The follow-up data indicates that 67% of the HS participants and 90% of the UG participants graduated from college with a STEM degree; for those who enrolled in graduate education, 61% and 43% enrolled in LLU, respectively. We conclude that structured SREs can be highly effective STEM strengthening interventions for both UG and HS students and may be a way to measurably increase institutional and biomedical

CASE REPORT MRI signal changes in the liver following multiple ...

African Journals Online (AJOL)

2008-02-10

Feb 10, 2008 ... Canadian Royal College certification or eligibility to write exam preferred. Locum positions are also available. Regina has a booming economy, no traffic and an international airport. Contact Larry Kliman, Business Manager tel: 306"529"3305 or e"mail larry@rarsk.com. RADIOLOGY POSITIONS.indd 1.

A qualitative study

African Journals Online (AJOL)

fatigue. Good social support, higher education, and better socioeconomic status are .... School of Public Health, Loma Linda University, Loma Linda,. California ... Address for correspondence: Dr. J. Roberts University of Mississippi,. School of ...

Tänavuse Roman Tavasti nimelise stipendiumi... / Kadri Mälk

Index Scriptorium Estoniae

Mälk, Kadri, 1958-

2008-01-01

2007. aasta Roman Tavasti nimelise stipendiumi pälvis Eesti Kunstiakadeemia ehtekunsti eriala üliõpilane Linda al-Assi, kes on sündinud Alzheerias, kasvanud Pärnus. Linda al-Assi ehteseeriast teemal "Andestus"

76 FR 70711 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2011-11-15

... L BEKKEDAHL, LARRY N BELL, MELODY C BIENIAWSKI, ANDREW J BIERBOWER, WILLIAM J BISHOP, CLARENCE T... BROWN, FRED L BROWN, STEPHANIE H BRUCE, SANDRA D BRYAN, PAUL F BRYAN, WILLIAM N BURROWS, CHARLES W BUTTRESS, LARRY D BUZZARD, CHRISTINE M CADIEUX, GENA E CALBOS, PHILIP T CALLAHAN, SAMUEL N CAMPAGNONE, MARI...

Effect of chronic administration of phenobarbital, or bromide, on pharmacokinetics of levetiracetam in dogs with epilepsy.

Science.gov (United States)

Muñana, K R; Nettifee-Osborne, J A; Papich, M G

2015-01-01

Levetiracetam (LEV) is a common add-on antiepileptic drug (AED) in dogs with refractory seizures. Concurrent phenobarbital administration alters the disposition of LEV in healthy dogs. To evaluate the pharmacokinetics of LEV in dogs with epilepsy when administered concurrently with conventional AEDs. Eighteen client-owned dogs on maintenance treatment with LEV and phenobarbital (PB group, n = 6), LEV and bromide (BR group, n = 6) or LEV, phenobarbital and bromide (PB-BR group, n = 6). Prospective pharmacokinetic study. Blood samples were collected at 0, 1, 2, 4, and 6 hours after LEV administration. Plasma LEV concentrations were determined by high-pressure liquid chromatography. To account for dose differences among dogs, LEV concentrations were normalized to the mean study dose (26.4 mg/kg). Pharmacokinetic analysis was performed on adjusted concentrations, using a noncompartmental method, and area-under-the-curve (AUC) calculated to the last measured time point. Compared to the PB and PB-BR groups, the BR group had significantly higher peak concentration (Cmax ) (73.4 ± 24.0 versus 37.5 ± 13.7 and 26.5 ± 8.96 μg/mL, respectively, P phenobarbital in dogs. Copyright © 2015 by the American College of Veterinary Internal Medicine.

Review of levoglucosan in glacier snow and ice studies: Recent progress and future perspectives.

Science.gov (United States)

You, Chao; Xu, Chao

2018-03-01

Levoglucosan (LEV) in glacier snow and ice layers provides a fingerprint of fire activity, ranging from modern air pollution to ancient fire emissions. In this study, we review recent progress in our understanding and application of LEV in glaciers, including analytical methods, transport and post-depositional processes, and historical records. We firstly summarize progress in analytical methods for determination of LEV in glacier snow and ice. Then, we discuss the processes influencing the records of LEV in snow and ice layers. Finally, we make some recommendations for future work, such as assessing the stability of LEV and obtaining continuous records, to increase reliability of the reconstructed ancient fire activity. This review provides an update for researchers working with LEV and will facilitate the further use of LEV as a biomarker in paleo-fire studies based on ice core records. Copyright © 2017 Elsevier B.V. All rights reserved.

Extreme Cost Growth: Themes from Six U.S. Air Force Major Defense Acquisition Programs

Science.gov (United States)

2015-01-01

See for example Linda D. Koontz , Polar Orbiting Environmental Satellites: Status, Plans, and Future Data Management Challenges, testimony before the...University Press, 2015. Koontz , Linda D., Polar-Orbiting Environmental Satellites: Status, Plans, and Future Data Management Challenges, testimony

Go4Life

Medline Plus

Full Text Available ... years ago 17,529 views Exercise your upper body at work like Linda with Go4Life's Wall Pushups. ... Trainer Sandy shows Linda how to do lower body exercises in her office with Go4Life's Toe Stand. ...

Efficacy of levetiracetam versus fosphenytoin for the recurrence of seizures after status epilepticus.

Science.gov (United States)

Nakamura, Kensuke; Inokuchi, Ryota; Daidoji, Hiroaki; Naraba, Hiromu; Sonoo, Tomohiro; Hashimoto, Hideki; Tokunaga, Kurato; Hiruma, Takahiro; Doi, Kent; Morimura, Naoto

2017-06-01

Benzodiazepines are used as first-line treatments for status epilepticus. Fosphenytoin (FPHT) is recommended for second-line therapy; however, intravenous injection of levetiracetam (LEV) may also be effective against status epilepticus. Herein, we compared the efficacy and safety of LEV as a second-line treatment for status epilepticus with FPHT in Japanese patients.Patients with status epilepticus were selected from the database of the Emergency and Critical Care Center of Hitachi General Hospital. The subjects were patients whose status epilepticus was successfully stopped by diazepam, and in whom FPHT or LEV was administered after diazepam. As LEV injections recently became clinically available in Japan, the choice of drug was determined by the treatment period. Thus, 21 patients who were intravenously injected with LEV as a second-line therapy and 42 matched patients (historical controls) who were treated with FPHT (1:2) were selected.The subjects had a mean age of 64.0 ± 2.2 years, and included 48 males and 15 females. The status epilepticus control rates of the FPHT and LEV groups did not differ significantly (81.0% [34/42] vs 85.1% [18/21], respectively; P  =  .69). As for serious adverse events, a reduction in blood pressure was observed in the FPHT group, but not in the LEV group. The oral anticonvulsant switching rates of the 2 groups were similar, but the same-drug switching rates of the FPHT and LEV groups were 8.1% and 77.8%, respectively.The efficacy of intravenous LEV injections after status epilepticus was equivalent to that of FPHT, and the incidence of adverse events was lower in the LEV group. LEV is effective and safe at preventing recurrent seizures after status epilepticus following benzodiazepine treatment.

Surnud mehe käsi / Veiko Belials

Index Scriptorium Estoniae

Belials, Veiko, 1966-

1997-01-01

Arvustus: Asimov, Isaac. Asum / inglise k. tlk. Linda Ariva. Tallinn : Eesti Raamat, 1985. (Mirabilia); Asimov, Isaac. Asum ja impeerium / inglise k. tlk. Linda Ariva. Tallinn : Eesti Raamat, 1989. (Mirabilia); Asimov, Isaac. Teine asum / inglise k. tlk. Indrek Elling. Tallinn : Eesti Raamat, 1996. (Mirabilia)

Job Loss and Infrastructure Job Creation Spending During the Recession

Science.gov (United States)

2010-05-26

Recession Linda Levine Specialist in Labor Economics May 26, 2010 Congressional Research Service 7-5700 www.crs.gov R40080 . c11173008 Report...2.8 million.23 Author Contact Information Linda Levine Specialist in Labor Economics llevine@crs.loc.gov, 7-7756

A randomized, double-blind, placebo-controlled crossover study of the effects of levetiracetam on cognition, mood, and balance in healthy older adults.

Science.gov (United States)

Schoenberg, Mike R; Rum, Ruba S; Osborn, Katie E; Werz, Mary Ann

2017-09-01

The cognitive and mood effects of levetiracetam (LEV) in older adults are not known. This study compared the cognitive and mood effects of LEV to placebo in healthy older adults. Cognitive, mood, and balance variables were compared between LEV and placebo using a randomized, double-blind, placebo-controlled crossover study with two 5-week treatment periods. Healthy volunteers (n = 20) aged 65-80 (mean age 72.4) received either LEV or placebo in which the LEV target dose was 1,000 mg/day. Volunteers, aged 65-80, were without epilepsy to limit potentially confounding the impact of seizures and/or underlying neuropathology on outcomes. LEV was initiated at 250 mg twice a day for 2 weeks, then increased to 500 mg twice a day for 2 weeks, and then tapered to 250 mg twice a day for 1 week. This was randomized with placebo for the two treatment arms. Measures included standardized neuropsychological, mood, and balance tests yielding 32 variables. Balance was assessed using subjective report (e.g., A-B neurotoxicity scale) and objective data (e.g., Berg Balance Scale). Average LEV serum concentration was 16.9 (standard deviation [SD} 7.7). Repeated-measures analysis of variance (ANOVA) found no differences between LEV and placebo phases for 29 (90.6%) of 32 variables including no change in balance. Performance on LEV was better than placebo on a visual memory (MCG Complex Figure Recall; p = 0.007) and two attention tests (Trail Making Test, Part A, p = 0.009; Stroop Interference, p = 0.004). There was a trend for greater irritability and fatigue (POMS Anger and Fatigue) during the LEV phase (p = 0.029, p = 0.035). Effect-size changes were generally small (Cohen d < 0.5). LEV was well tolerated in this elderly population in terms of cognition, mood, and balance. When anticonvulsant medication is indicated for older adults, LEV has pharmacokinetic advantages, and these data indicate no adverse impact on cognition or balance. Wiley Periodicals, Inc. © 2017 International

Immunoglobulin changes in boars exposed to administration of levamisole and exogenous adrenocorticotropic hormone

Directory of Open Access Journals (Sweden)

Bilandžić Nina

2012-01-01

Full Text Available The objective of this paper was to determine the effect of levamisole (LEV on immunoglobulin concentration in the serum of boars exposed to 3-day stress induced by exogenous ACTH. Boars were assigned to 4 groups (n=7. The first group received LEV for 3 days (2.5 mg/kg BW, the second group received ACTH (10 μg/kg BW for 3 days and the third group received LEV for 3 consecutive days and ACTH for the following 3 days (2.5 mg/kg BW; ACTH 10 μg/kg BW. The control group received saline solution during the 6 days. Concentrations of cortisol, total protein, globulin, albumin and immunoglobulin (IgG, IgA and IgM were determined during treatments and on the 16th day post-administration. Cortisol concentration was increased in both ACTH treated groups during all three days of administration and the day after the last ACTH treatment (p<0.05. ACTH increased total protein levels during the stress period and over the next 16 days (p<0.05. However, in the LEV+ACTH group total protein levels were elevated only on day 1 and 2 of ACTH injection (p<0.05 and after the end of treatment on day 11 and 22 (p<0.05. LEV stimulated the increase of protein concentrations compared to control values after LEV treatment, on days 5, 14, 18 and 22 (p<0.05. Serum albumins were not affected by LEV or ACTH treatment. Globulin concentrations were increased throughout and on the 16th day after administration of ACTH in the ACTH and LEV+ACTH groups (p<0.05. Globulin concentrations did not differ between LEV and control groups of boars. ACTH treatment elevated serum IgG concentration during the stress period (p<0.05 and over the next 16 days (p<0.05. However, in the LEV+ACTH group of boars, IgG levels were elevated on days 1 and 3 after ACTH injection (p<0.05 and days 1 and 5 in the post-treatment period (p<0.05. LEV had no impact on IgG levels compared to the control boars. However, increased IgA concentrations in boars treated with LEV were determined on day 2 (p<0.05 and day 11 (p

Svetonosnoje iskusstvo / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2003-01-01

Katariina käigust Tallinnas. vitraažitöökojast-galeriist Domini Canes, seal töötavatest vitraažikunstnikest Dolores Hoffmannist ja Andrei Lobanovist, nende töödest nii Eestis kui ka välismaal. Dolores Hoffmann räägib vitraažist

‘The political deadlock is life’: Boris and the satire of contemporary Italian media and cultural industries

Directory of Open Access Journals (Sweden)

Giacomo Boitani

2014-12-01

Full Text Available ‘Il pareggio elettorale è la vita’: Boris e la satira dei mass media italiani e dell’industria culturale odierni  Nel 2007 il network satellitare Fox Italia ha cominciato la produzione di Boris, una serie comica del genere mockumentary messa in onda sui canali Sky Italia dal 2007 al 2010. La trama di Boris narra le peripezie di una troupe televisiva alle prese con la produzione di una soap-opera per la RAI. In Italia la serie è presto diventata un prodotto ‘cult’. Nella serie Boris i pigri e opportunisti membri della troupe televisiva fittizia sono rappresentati come succubi delle ripercussioni che gli sviluppi politici nel Paese hanno sul servile network per il quale lavorano. Gli attori nella soap-opera fittizia vengono rimpiazzati e la trama stessa della soap-opera viene riscritta a seconda delle nuove coalizioni che vengono formate in Parlamento e i membri della troupe sono costantemente alla ricerca di raccomandazioni e protezione politica. Per quanto satirizza lo stato del Paese, Boris mette anche in discussione il fatto stesso che l’industria culturale Italiana corrente possa produrre un discorso significativo. Con riferimento alla teorizzazione della ‘parodia’ da parte di Linda Hutcheon, questo articolo discute la rappresentazione che Boris ha tratteggiato dell’industria culturale, analizza il rapporto esistente tra la serie e tradizioni comiche Italiane che l’hanno preceduta (la ‘commedia all’italiana’ e il modo in cui l’ironia implementata dalla serie ricalca e/o diverge da quella tipica delle serie mockumentary estere che l’hanno ispirata (Arrested Development e The Larry Sanders Show.

Leading edge vortices in lesser long-nosed bats occurring at slow but not fast flight speeds

International Nuclear Information System (INIS)

Muijres, Florian T; Christoffer Johansson, L; Hedenström, Anders; Winter, York

2014-01-01

Slow and hovering animal flight creates high demands on the lift production of animal wings. Steady state aerodynamics is unable to explain the forces required and the most commonly used mechanism to enhance the lift production is a leading edge vortex (LEV). Although LEVs increase the lift, they come at the cost of high drag. Here we determine the flow above the wing of lesser long-nosed bats at slow and cruising speed using particle image velocimetry (PIV). We find that a prominent LEV is present during the downstroke at slow speed, but not at cruising speed. Comparison with previously published LEV data from a robotic flapper inspired by lesser long-nosed bats suggests that bats should be able to generate LEVs at cruising speeds, but that they avoid doing so, probably to increase flight efficiency. In addition, at slow flight speeds we find LEVs of opposite spin at the inner and outer wing during the upstroke, potentially providing a control challenge to the animal. We also note that the LEV stays attached to the wing throughout the downstoke and does not show the complex structures found in insects. This suggests that bats are able to control the development of the LEV and potential control mechanisms are discussed. (papers)

Unsteady behavior of leading-edge vortex and diffuser stall in a centrifugal compressor with vaned diffuser

Science.gov (United States)

Fujisawa, Nobumichi; Hara, Shotaro; Ohta, Yutaka

2016-02-01

The characteristics of a rotating stall of an impeller and diffuser and the evolution of a vortex generated at the diffuser leading-edge (i.e., the leading-edge vortex (LEV)) in a centrifugal compressor were investigated by experiments and numerical analysis. The results of the experiments revealed that both the impeller and diffuser rotating stalls occurred at 55 and 25 Hz during off-design flow operation. For both, stall cells existed only on the shroud side of the flow passages, which is very close to the source location of the LEV. According to the CFD results, the LEV is made up of multiple vortices. The LEV is a combination of a separated vortex near the leading- edge and a longitudinal vortex generated by the extended tip-leakage flow from the impeller. Therefore, the LEV is generated by the accumulation of vorticity caused by the velocity gradient of the impeller discharge flow. In partial-flow operation, the spanwise extent and the position of the LEV origin are temporarily transmuted. The LEV develops with a drop in the velocity in the diffuser passage and forms a significant blockage within the diffuser passage. Therefore, the LEV may be regarded as being one of the causes of a diffuser stall in a centrifugal compressor.

Graphene oxide-facilitated transport of levofloxacin and ciprofloxacin in saturated and unsaturated porous media.

Science.gov (United States)

Sun, Kaixuan; Dong, Shunan; Sun, Yuanyuan; Gao, Bin; Du, Wenchao; Xu, Hongxia; Wu, Jichun

2018-04-15

In this work, effects of graphene oxide (GO) on the co-transport of the two typical Fluoroquinolones (FQs) - levofloxacin (LEV) and ciprofloxacin (CIP) in saturated and unsaturated quartz sand media were studied. The adsorption isotherms showed that GO had much larger sorption capacities to LEV and CIP than sand with the largest Langmuir adsorption capacity of 409 mg g -1 (CIP-GO); while the sorption affinity of the two FQs onto the two adsorbents might follow the order of CIP-sand > LEV-sand > LEV-GO > CIP-GO. GO promoted the mobility of the two FQs in both saturated and unsaturated porous media due to its strong mobility and sorption capacity. The GO-bound LEV/CIP was responsible for the LEV/CIP transport in the porous media, and transport of GO-bound FQs increased with the increasing of initial GO concentration. Under unsaturated conditions, moisture showed little effect on the transport of GO-bound CIP; however, the mobility of GO-bound LEV reduced with the decreasing of moisture content, suggesting the transport of adsorbed LEV from GO to air-water interface. GO sorption reduced the antibacterial ability of the two FQs, but they were still effective in inhibiting E. coli growth. Copyright © 2018 Elsevier B.V. All rights reserved.

Single-tube linear DNA amplification for genome-wide studies using a few thousand cells

NARCIS (Netherlands)

Shankaranarayanan, P.; Mendoza-Parra, M.A.; Gool, van W.; Trindade, L.M.; Gronemeyer, H.

2012-01-01

Linear amplification of DNA (LinDA) by T7 polymerase is a versatile and robust method for generating sufficient amounts of DNA for genome-wide studies with minute amounts of cells. LinDA can be coupled to a great number of global profiling technologies. Indeed, chromatin immunoprecipitation coupled

Fermilab History and Archives Project | Building the Energy

Science.gov (United States)

filled with off-shift workers and other well-wishers as the champagne was broken out. The events leading the beam slightly. Director Leon Lederman pours champagne for Linda Klamp as she "spreads the news" on Sunday, July 3 Director Leon Lederman pours champagne for Linda Klamp as she "

Reproductive toxicity after levetiracetam administration in male rats: Evidence for role of hormonal status and oxidative stress.

Directory of Open Access Journals (Sweden)

Merve Baysal

Full Text Available Levetiracetam (LEV is an antiepileptic drug commonly used in the treatment of epilepsy because of its excellent safety profile in all age groups. It is remarkable that there are no studies evaluating the toxic effects of this drug on the male reproductive system, as it is commonly used in male patients of reproductive age. From this point of view, our aim was to evaluate the possible toxic effects of LEV on the male reproductive system. Therefore, LEV was administered to male rats orally at 50, 150, and 300 mg/kg for 70 consecutive days. At the end of this period, alterations to body and organ weights were calculated, and sperm concentration, motility, and morphology were investigated by a computer-assisted sperm analysis system. Sperm DNA damage was determined by comet assay and histopathological examination of the testes was carried out. Serum testosterone, follicle-stimulating hormone (FSH, and luteinizing hormone (LH levels were measured by ELISAs to determine the effects of hormonal status, while glutathione, superoxide dismutase, catalase, and malondialdehyde levels in the testes were measured by colorimetric assay kits to determine the role of oxidative status in potential toxicity. According to the results, sperm quality was decreased by LEV treatment in a dose-dependent manner. LEV induced significant DNA damage in the 150 and 300 mg/kg LEV-administered groups. Histopathology of the testes showed that LEV resulted in testicular injury in the 300 mg/kg LEV-administered group. Serum testosterone, FSH, and LH levels were significantly decreased in the 300 mg/kg LEV-administered group. Glutathione, superoxide dismutase, and catalase levels were significantly decreased in all experimental groups while malondialdehyde levels were significantly increased in 150 and 300 mg/kg LEV-administered groups. According to these results, it was determined that LEV administration decreased sperm quality and it was alleged that hormonal alteration and

Brivaracetam augments short-term depression and slows vesicle recycling.

Science.gov (United States)

Yang, Xiaofeng; Bognar, Joseph; He, Tianyu; Mohammed, Mouhari; Niespodziany, Isabelle; Wolff, Christian; Esguerra, Manuel; Rothman, Steven M; Dubinsky, Janet M

2015-12-01

Brivaracetam (BRV) decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle glycoprotein 2A (SV2A) with a higher affinity than the antiepileptic drug levetiracetam (LEV). Experiments were performed to determine if BRV acted similarly to LEV to induce or augment short-term depression (STD) under high-frequency neuronal stimulation and slow synaptic vesicle recycling. Electrophysiologic field excitatory postsynaptic potential (fEPSP) recordings were made from CA1 synapses in rat hippocampal slices loaded with BRV or LEV during intrinsic activity or with BRV actively loaded during hypertonic stimulation. STD was examined in response to 5 or 40 Hz stimulus trains. Presynaptic release of FM1-43 was visualized using two-photon microscopy to assess drug effects upon synaptic vesicle mobilization. When hippocampal slices were incubated in 0.1-30 μm BRV or 30 μm-1 mm LEV for 3 h, the relative CA1 field EPSPs decreased over the course of a high-frequency train of stimuli more than for control slices. This STD was frequency- and concentration-dependent, with BRV being 100-fold more potent than LEV. The extent of STD depended on the length of the incubation time for both drugs. Pretreatment with LEV occluded the effects of BRV. Repeated hypertonic sucrose treatments and train stimulation successfully unloaded BRV from recycling vesicles and reversed BRVs effects on STD, as previously reported for LEV. At their maximal concentrations, BRV slowed FM1-43 release to a greater extent than in slices loaded with LEV during prolonged stimulation. BRV, similar to LEV, entered into recycling synaptic vesicles and produced a frequency-dependent decrement of synaptic transmission at 100-fold lower concentrations than LEV. In addition, BRV slowed synaptic vesicle mobilization more effectively than LEV, suggesting that these drugs may modify multiple functions of the synaptic vesicle protein SV2A to curb synaptic transmission and limit epileptic activity

Effectiveness of intravenous levetiracetam as an adjunctive treatment in pediatric refractory status epilepticus.

Science.gov (United States)

Kim, Jon Soo; Lee, Jeong Ho; Ryu, Hye Won; Lim, Byung Chan; Hwang, Hee; Chae, Jong-Hee; Choi, Jieun; Kim, Ki Joong; Hwang, Yong Seung; Kim, Hunmin

2014-08-01

Intravenous levetiracetam (LEV) has been shown to be effective and safe in treating adults with refractory status epilepticus (SE). We sought to investigate the efficacy and safety of intravenous LEV for pediatric patients with refractory SE. We performed a retrospective medical-record review of pediatric patients who were treated with intravenous LEV for refractory SE. Clinical information regarding age, sex, seizure type, and underlying neurological status was collected. We evaluated other anticonvulsants that were used prior to administration of intravenous LEV and assessed loading dose, response to treatment, and any adverse events from intravenous LEV administration. Fourteen patients (8 boys and 6 girls) received intravenous LEV for the treatment of refractory SE. The mean age of the patients was 4.4 ± 5.5 years (range, 4 days to 14.6 years). Ten of the patients were neurologically healthy prior to the refractory SE, and the other 4 had been previously diagnosed with epilepsy. The mean loading dose of intravenous LEV was 26 ± 4.6 mg/kg (range, 20-30 mg/kg). Seizure termination occurred in 6 (43%) of the 14 patients. In particular, 4 (57%) of the 7 patients younger than 2 years showed seizure termination. No immediate adverse events occurred during or after infusions. The current study demonstrated that the adjunctive use of intravenous LEV was effective and well tolerated in pediatric patients with refractory SE, even in patients younger than 2 years. Intravenous LEV should be considered as an effective and safe treatment option for refractory SE in pediatric patients.

A Behavioral Treatment for Traumatic Brain Injury-Associated Visual Dysfunction Based on Adult Cortical Plasticity

Science.gov (United States)

2014-12-01

Zomet, Lev, Yehezkel, Sterkin & Levi, 2012b) and developmental object and face agnosia (Lev, Gilaie-Dotan, Gotthilf-Nezri, Yehezkel, Brooks, Perry...followed by mid-level perceptual improvements in developmental object and face agnosia . Dev Sci, Lev, M., Ludwig, K., Gilaie-Dotan, S., Voss, S

The use of augmented reality glasses in central line simulation: "see one, simulate many, do one competently, and teach everyone"

Directory of Open Access Journals (Sweden)

Huang CY

2018-05-01

Full Text Available Cynthia Y Huang,1 Jonathan B Thomas,2 Abdullah Alismail,3 Avi Cohen,1 Waleed Almutairi,3 Noha S Daher,4 Michael H Terry,5 Laren D Tan1,3 1Department of Medicine, Division of Pulmonary, Critical Care, Hyperbaric and Sleep Medicine, Loma Linda University, Loma Linda, CA, USA; 2Zapara School of Business, La Sierra University, Riverside, CA, USA; 3Cardiopulmonary Sciences Department, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA; 4Department of Allied Health Studies, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA; 5Department of Respiratory Care, Loma Linda University Medical Center, Loma Linda, CA, USA Objective: The aim of this study was to investigate the feasibility of using augmented reality (AR glasses in central line simulation by novice operators and compare its efficacy to standard central line simulation/teaching. Design: This was a prospective randomized controlled study enrolling 32 novice operators. Subjects were randomized on a 1:1 basis to either simulation using the augmented virtual reality glasses or simulation using conventional instruction. Setting: The study was conducted in tertiary-care urban teaching hospital. Subjects: A total of 32 adult novice central line operators with no visual or auditory impairments were enrolled. Medical doctors, respiratory therapists, and sleep technicians were recruited from the medical field. Measurements and main results: The mean time for AR placement in the AR group was 71±43 s, and the time to internal jugular (IJ cannulation was 316±112 s. There was no significant difference in median (minimum, maximum time (seconds to IJ cannulation for those who were in the AR group and those who were not (339 [130, 550] vs 287 [35, 475], p=0.09, respectively. There was also no significant difference between the two groups in median total procedure time (524 [329, 792] vs 469 [198, 781], p=0.29, respectively. There was a significant

The leading-edge vortex of yacht sails

Science.gov (United States)

Arredondo-Galeana, Abel; Viola, Ignazio Maria

2017-11-01

We experimentally show, for the first time, that a stable Leading-Edge Vortex (LEV) can be formed on an asymmetric spinnaker, which is a high-lift sail used by yachts to sail downwind. We tested a 3D printed rigid sail in a water flume at a chord-based Reynolds number of ca. 104. We found that on the leeward side of the sail (the suction side), the flow separates at the leading edge reattaching further downstream and forming a stable LEV. The LEV grows in diameter from the root to the tip of the sail, where it merges with the tip vortex. We detected the LEV using the γ criterion, and we verified its stability over time. The lift contribution provided by the LEV was computed solving a complex potential model of each sail section. This analysis indicated that the LEV provides a substantial contribution to the total sail's lift. These findings suggest that the maximum lift of low-aspect-ratio wings with a sharp leading edge, such as spinnakers, can be enhanced by promoting a stable LEV. This work was funded by the Consejo Nacional de Ciencia y Tecnologia (CONACYT).

Developing a clinical proton accelerator facility: Consortium-assisted technology transfer

International Nuclear Information System (INIS)

Slater, J.M.; Miller, D.W.; Slater, J.W.

1991-01-01

A hospital-based proton accelerator facility has emerged from the efforts of a consortium of physicists, engineers and physicians from several high-energy physics laboratories, industries and universities, working together to develop the requirements and conceptual design for a clinical program. A variable-energy medical synchrotron for accelerating protons to a prescribed energy, intensity and beam quality, has been placed in a hospital setting at Loma Linda University Medical Center for treating patients with localized cancer. Treatments began in October 1990. Scientists from Fermi National Accelerator Laboratory; Harvard Cyclotron Laboratory; Lawrence Berkeley Laboratories; the Paul Scherrer Institute; Uppsala, Sweden; Argonne, Brookhaven and Los Alamos National Laboratories; and Loma Linda University, all cooperated to produce the conceptual design. Loma Linda University contracted with Fermi National Accelerator Laboratory to design and build a 250 MeV synchrotron and beam transport system, the latter to guide protons into four treatment rooms. Lawrence Berkeley Laboratories consulted with Loma Linda University on the design of the beam delivery system (nozzle). A gantry concept devised by scientists at Harvard Cyclotron Laboratory, was adapted and fabricated by Science Applications International Corporation. The control and safety systems were designed and developed by Loma Linda University Radiation Research Laboratory. Presently, the synchrotron, beam transport system and treatment room hardware have been installed and tested and are operating satisfactorily

Reflections on the first twenty-five years of the University of Malawi ...

African Journals Online (AJOL)

to take up this role until after having the opportunity to learn from the first holder of this post, the Australian Geoffrey. Dahlenburg. The College of Medicine opened its doors in September ... Executive Dean of the COM, first reported to the world ... Loma Linda University School of Public Health, Loma Linda, California, USA.

Asset Management Process (AMP) Improvement Project: Final Report of Findings and Recommendations

Science.gov (United States)

2009-10-01

Beach, Sue Meade-Lutz, Gary Reid, Deanna Tauvela, and Larry Majure . John Gorman served as the event’s Process Owner. INVESTIGATIONAL QUESTION The...Reid, Deanna Tauvela, and Larry Majure . John Gorman served as the event’s Process Owner. INVESTIGATIONAL QUESTION For years, the Center has...Provide custodians with receipts that are electronically tracked and use the receipt transaction to trigger forced asset transfers in ERP. See Appendix F

ORGANIZED SYMPOSIA, ANNUAL MEETING SAEA, LITTLE ROCK, ARKANSAS, FEBRUARY 1990.

OpenAIRE

Anonymous

1990-01-01

Education: the key to sustained development in the rural south, Brady J. Deaton; The design, funding and extension of interdisciplinary water quality research, Larry D. Sanders; Fee access to recreational activities by private landowners, Dennis K. Smith; A new challenge for agricultural economics: public policy education & analysis during program implementation, Larry D. Sanders; Software design and development for the direct support of extension programs and extension field staff, G.A. Barn...

Ears and Eyes in the Sky: The Evolution of Manned Airborne ISR

Science.gov (United States)

2012-05-25

immeasurably grateful. I would be remiss not to mention Mr. Larry Tart. His work on manned airborne ISR has educated and inspired the latest...comprehensive summary of airborne ISR such as that presented in this thesis. Several prominent works contain significant sections on airborne ISR. Larry ...Historic Cryptographic Collection, RG 457, Box 1369, NARA. 77 William E. Burrows , By Any Means Necessary (New York, NY: Farrar, Straus, and Giroux

Independent Assessment of the Afghan National Security Forces

Science.gov (United States)

2014-02-01

to prolong assignment and “ burrow in”  Increased cost compared to military or civilian U.S. – Afghanistan Bilateral  Simplifies relationships and...227. 248 Larry P. Goodson. Afghanistan’s Endless War: State Failure, Regional Pol- itics, and the Rise of the Taliban. Seattle: University of...Goodson, Larry P. Afghanistan’s Endless War: State Failure, Regional Poli- tics, and the Rise of the Taliban. Seattle: University of Washington Press

Brand-to-generic levetiracetam switch in patients with epilepsy in a routine clinical setting.

Science.gov (United States)

Markoula, Sofia; Chatzistefanidis, Dimitrios; Gatzonis, Stylianos; Siatouni, Anna; Siarava, Eleftheria; Verentzioti, Anastasia; Kyritsis, Athanassios P; Patsalos, Philip N

2017-05-01

The therapeutic equivalence of generic and brand antiepileptic drugs, based on studies performed on healthy volunteers, has been questioned. We compare, in a routine clinical setting, brand versus generic levetiracetam (LEV) bioequivalence in patients with epilepsy and also the clinical efficacy and tolerability of the substitution. A prospective, open-label, non-randomized, steady-state, multiple-dose, bioequivalence study was conducted in 12 patients with epilepsy (5 females), with a mean age of 38.4±16.2 years. Patients treated with the brand LEV (Keppra; UCB Pharma) were closely followed for a four-week period and subsequently switched to a generic LEV (Pharmaten) and followed for another four-week period. Blood samples were collected at the end of each 4-week period, during a dose interval for each formulation, for LEV concentration measurements by liquid chromatography mass spectrometry. Steady-state area under the curve (AUC) and peak plasma concentration (Cmax) data were subjected to conventional average bioequivalence analysis. Secondary clinical outcomes, including seizure frequency and adverse events, were recorded. Patients had epilepsy for a mean period of 14.1±10.6years and the mean daily LEV dose was 2583.3±763.7mg. The mean AUC±SD and Cmax±SD was 288.4±86.3(mg/L)h and 37.8±10.4mg/L respectively for brand LEV and 319.2±104.7(mg/L)h and 41.6±12.3mg/L respectively for the generic LEV. Statistic analysis showed no statistical significant difference in bioequivalence. Also, no change in seizures frequency and/or adverse events was recorded. In our clinical setting, generic LEV was determined to be bioequivalent to brand LEV. Furthermore, seizures frequency or/and adverse events were not affected upon switching from brand to generic LEV. Copyright © 2017 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Silk or Spandex?: China’s Problematic One Road, One Belt Plan to Expand its Economic Boundaries as Seen Through the Lens of American, British, and Japanese Experience

Science.gov (United States)

2016-04-05

information, including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services, Directorate for Information...taken from Crafts’ research, for Great Britain and Japan. 49 Linda MacGrain Herkenhoff, “A Socially Intelligent Approach to Global Remuneration ...and Slavery. Gordonsville: Palgrave Macmillan, 2005. Herkenhoff, Linda MacGrain. "A Socially Intelligent Approach to Global Remuneration ." World

Steward of Headwaters: U.S. Army Corps of Engineers, St. Paul District, 1975-2000

Science.gov (United States)

2012-01-01

to their shells, thereby preventing them from migrating or burrowing .73 The St. Paul District initiated a monitoring process of the zebra mussel at...P ro je ct s 4 104 Strong Move, 13 February 1997, File LaFarge Ho Chunk, Box 6410, SPDAR; Ron Wilber to Larry Garvin, HoChunk Researcher, 10...July 1987, File Congressional Correspondence, Box 6412, SPDAR. 39 Larry and Diane Uhlir to Mr. Gregg Struss, Resource Manager, Gull Lake Recreation

Mike O’Callaghan Federal Medical Center Campus Environmental Assessment

Science.gov (United States)

2012-03-01

and therefore is protected under the Endangered Species Act (ESA). The western burrowing owl (Athene cunicularia) is a former USFWS C- 2 species and...JVanHavel@dot . state . nv.us> ; keiba.crear@snwa.com; LANGSTON@ClarkCountyNV. gov; ~arry . Tamashiro@ lvvwd. com <mailto : Larry . Tamashi! r o@lvvwd...Wardlaw; JVanHavel @dot .state.nv .us; keiba . c rear@snwa . com; Rodney Langston; Larry . Tamashiro@l vvwd.com; laura. j a cobsen@lvvwd . com

The Lens of Power: Aerial Reconnaissance and Diplomacy in the Airpower Century

Science.gov (United States)

2013-01-01

comments at Burrows , By Any Means Necessary, 321. These comments are echoed by Larry Tart at Burrows , By Any Means Necessary, xvi. 1143 As if to make this...For example: William Burrows , Paul Lashmar, L. Parker Temple, Chris Pocock, Gregory Pedlow, and Donald Welzenbach. Their works are covered more...reconnaissance. For example, Larry Tart and Robert Keefe’s 2001 The Price of Vigilance was written to raise awareness about reconnaissance crews who never

[Epileptic encephalopathy associated with forced normalization after administration of levetiracetam].

Science.gov (United States)

Kikuchi, Takahiro; Kato, Mitsuhiro; Takahashi, Nobuya; Nakamura, Kazuyuki; Hayasaka, Kiyoshi

2013-09-01

Here we report a case of a 10-year-old female with unclassified epileptic encephalopathy who showed forced normalization after administration of levetiracetam (LEV). She initially presented with intractable tonic and myoclonic seizures that were observed about 10 times a day along with frequent multifocal sharp and slow wave complexes on electroencephalography (EEG). We were forced to decrease the topiramate dose because of the appearance of nystagmus, and her myoclonic seizures became worse. We added LEV (250 mg/day) and her tonic and myoclonic seizures disappeared one day after initiation of LEV administration. However, she showed hyporesponsiveness and akinesia. The disappearance of paroxysmal discharges on EEG confirmed the diagnosis of forced normalization. Despite continuous administration of LEV, tonic and myoclonic seizures relapsed within a month but her psychotic symptoms resolved simultaneously. To the best of our knowledge, this is the first reported case of forced normalization after LEV administration. It should be noted that LEV may cause forced normalization although it can be started at an adequate dosage.

Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery: the HELLO trial.

Science.gov (United States)

Bähr, Oliver; Hermisson, Mirjam; Rona, Sabine; Rieger, Johannes; Nussbaum, Susanne; Körtvelyessy, Peter; Franz, Kea; Tatagiba, Marcos; Seifert, Volker; Weller, Michael; Steinbach, Joachim P

2012-02-01

Levetiracetam (LEV) is a newer anticonvulsant with a favorable safety profile. There seem to be no relevant drug interactions, and an intravenous formulation is available. Therefore, LEV might be a suitable drug for the perioperative anticonvulsive therapy of patients with suspected brain tumors undergoing neurosurgery. In this prospective study (NCT00571155) patients with suspected primary brain tumors and tumor-related seizures were perioperatively treated with oral and intravenous LEV up to 4 weeks before and until 4 weeks after a planned neurosurgical procedure. Thirty patients with brain tumor-related seizures and intended neurosurgery were included. Three patients did not undergo the scheduled surgery after enrollment, and two patients were lost to follow-up. Therefore, 25 patients were fully evaluable. After initiation of therapy with LEV, 100% of the patients were seizure-free in the pre-surgery phase (3 days up to 4 weeks before surgery), 88% in the 48 h post-surgery phase and 84% in the early follow-up phase (48 h to 4 weeks post surgery). Treatment failure even after dose escalation to 3,000 mg/day occurred in three patients. No serious adverse events related to the treatment with LEV occurred. Our data show the feasibility and safety of oral and intravenous LEV in the perioperative treatment of tumor-related seizures. Although this was a single arm study, the efficacy of LEV appears promising. Considering the side effects and interactions of other anticonvulsants, LEV seems to be a favorable option in the perioperative treatment of brain tumor-related seizures.

Rotational accelerations stabilize leading edge vortices on revolving fly wings.

Science.gov (United States)

Lentink, David; Dickinson, Michael H

2009-08-01

The aerodynamic performance of hovering insects is largely explained by the presence of a stably attached leading edge vortex (LEV) on top of their wings. Although LEVs have been visualized on real, physically modeled, and simulated insects, the physical mechanisms responsible for their stability are poorly understood. To gain fundamental insight into LEV stability on flapping fly wings we expressed the Navier-Stokes equations in a rotating frame of reference attached to the wing's surface. Using these equations we show that LEV dynamics on flapping wings are governed by three terms: angular, centripetal and Coriolis acceleration. Our analysis for hovering conditions shows that angular acceleration is proportional to the inverse of dimensionless stroke amplitude, whereas Coriolis and centripetal acceleration are proportional to the inverse of the Rossby number. Using a dynamically scaled robot model of a flapping fruit fly wing to systematically vary these dimensionless numbers, we determined which of the three accelerations mediate LEV stability. Our force measurements and flow visualizations indicate that the LEV is stabilized by the ;quasi-steady' centripetal and Coriolis accelerations that are present at low Rossby number and result from the propeller-like sweep of the wing. In contrast, the unsteady angular acceleration that results from the back and forth motion of a flapping wing does not appear to play a role in the stable attachment of the LEV. Angular acceleration is, however, critical for LEV integrity as we found it can mediate LEV spiral bursting, a high Reynolds number effect. Our analysis and experiments further suggest that the mechanism responsible for LEV stability is not dependent on Reynolds number, at least over the range most relevant for insect flight (100wind turbines at much higher Reynolds numbers suggest that even large flying animals could potentially exploit LEV-based force augmentation during slow hovering flight, take-offs or landing

Formal Specification and Analysis of Cloud Computing Management

Science.gov (United States)

2012-01-24

te r Cloud Computing in a Nutshell We begin this introduction to Cloud Computing with a famous quote by Larry Ellison: “The interesting thing about...the wording of some of our ads.” — Larry Ellison, Oracle CEO [106] In view of this statement, we summarize the essential aspects of Cloud Computing...1] M. Abadi, M. Burrows , M. Manasse, and T. Wobber. Moderately hard, memory-bound functions. ACM Transactions on Internet Technology, 5(2):299–327

Survival benefit of levetiracetam in patients treated with concomitant chemoradiotherapy and adjuvant chemotherapy with temozolomide for glioblastoma multiforme.

Science.gov (United States)

Kim, Young-Hoon; Kim, Tackeun; Joo, Jin-Deok; Han, Jung Ho; Kim, Yu Jung; Kim, In Ah; Yun, Chang-Ho; Kim, Chae-Yong

2015-09-01

A chemosensitizing effect of levetiracetam (LEV) has been suggested because LEV inhibits O-6 methylguanine-DNA methyltransferase (MGMT). However, the survival benefit of LEV has not been clinically documented. The objective of this study was to assess the survival benefit of LEV compared with other antiepileptic drugs as a chemosensitizer to temozolomide for patients with glioblastoma. In total, 103 consecutive patients with primary glioblastoma who received concomitant chemoradiotherapy and adjuvant chemotherapy with temozolomide were retrospectively reviewed, and 58 patients (56%) received LEV during temozolomide chemotherapy for at least 3 months. A Cox regression survival analysis was performed to adjust for confounding factors, including age, extent of lesion, Karnofsky performance scale score, extent of removal, and MGMT promoter methylation status. The median progression-free survival (PFS) and overall survival (OS) for patients who received LEV in combination with temozolomide (PFS: median, 9.4 months; 95% confidence interval [CI], 7.5-11.3 months; OS: median, 25.7 months; 95% CI, 21.7-29.7 months) were significantly longer than those for patients who did not receive LEV (PFS: median, 6.7 months; 95% CI, 5.8-7.6 months; OS: median, 16.7 months; 95% CI, 12.1-21.3 months; P = .010 and P = .027, respectively). In multivariate analysis, the variables that were identified as significant prognostic factors for OS were preoperative Karnofsky performance scale score (hazard ratio [HR], 0.37; P = .016), MGMT promoter methylation (HR, 0.30; P = .002), and receipt of LEV (HR, 0.31; P benefit in patients with glioblastoma who receive temozolomide-based chemotherapy. A prospective randomized study may be indicated. © 2015 American Cancer Society.

Graphene Oxide Affects Mobility and Antibacterial Ability of Levofloxacin and Ciprofloxacin in Saturated and Unsaturated Porous Media

Science.gov (United States)

Kaixuan, S.

2017-12-01

Understand the fate and impact of fluoroquinolone antibiotics (FQs) in soil and groundwater systems is critical to the safety of ecosystem and public health. In this work, laboratory batch sorption, column transport, and bacterial growth experiments were conducted to improve current understanding of the interactions between two typical FQs (levofloxacin (LEV) and ciprofloxacin (CIP)) and graphene oxide (GO) in quartz sand media under various conditions. Studies showed that both GO and quartz sand adsorbed LEV and CIP in aqueous solutions and sand was capable to compete with GO for the antibiotics. While GO showed much larger sorption capacity, the sand had stronger sorption affinity to the two antibiotics. As a result, neither LEV nor CIP showed any signs of breakthrough in saturated or unsaturated porous media. When the two antibiotics were premixed with GO, their mobility in porous media increased for both saturate and unsaturated conditions and the amount of LEV or CIP in the effluents increased with the increasing of initial GO concentration. During their transport in saturated porous media, some of the GO-bound antibiotics, especially those sorbed via relatively weak interactions, transferred from GO to the quartz sand. Under unsaturated conditions, GO-bound LEV might also transfer from GO to the air-water interface due to the strong affiliation between LEV and air-water interface. Sorption onto GO reduced the antibacterial ability of LEV and CIP, however, the GO-bound antibiotics still effectively inhibited the growth of E coli. Findings from this work indicated that mobile GO affected not only the mobility but also the ecotoxicity of LEV and CIP in porous media.

Unsteady fluid dynamics around a hovering wing

Science.gov (United States)

Krishna, Swathi; Green, Melissa; Mulleners, Karen

2017-11-01

The unsteady flow around a hovering flat plate wing has been investigated experimentally using particle image velocimetry and direct force measurements. The measurements are conducted on a wing that rotates symmetrically about the stroke reversal at a reduced frequency of k = 0.32 and Reynolds number of Re = 220 . The Lagrangian finite-time Lyapunov exponent method is used to analyse the unsteady flow fields by identifying dynamically relevant flow features such as the primary leading edge vortex (LEV), secondary vortices, and topological saddles, and their evolution within a flapping cycle. The flow evolution is divided into four stages that are characterised by the LEV (a)emergence, (b)growth, (c)lift-off, and (d)breakdown and decay. Tracking saddle points is shown to be helpful in defining the LEV lift-off which occurs at the maximum stroke velocity. The flow fields are correlated with the aerodynamic forces revealing that the maximum lift and drag are observed just before LEV lift-off. The end of wing rotation in the beginning of the stroke stimulates a change in the direction of the LEV growth and the start of rotation at the end of the stroke triggers the breakdown of the LEV.

Vitjaz na rasputje / Lev Golub

Index Scriptorium Estoniae

Golub, Lev

2008-01-01

Autor analüüsib põhjusi, mis on Eesti majanduse praeguse keerulise seisuni viinud, valitsuse majanduspoliitika kriitika. Soovitus valitsusele ja Riigikogule kriisikomisjoni loomiseks, mis lisaks erinevatele meetmetele peaks eelkõige sotsiaalselt nõrgemaid kaitsma

Dokazatelstvo ot obratnogo / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2008-01-01

UNESCO maailmapärandi nimekirja kuuluva Tallinna vanalinna kaitsetsooni loomisest ja kõrghoonete ehitamisest vanalinna läheduses. UNESCO komitee nõuab vanalinna puhvertsooni loomise kava ja ülevaadet Tallinna kõrghoonete teemaplaneeringust

Tvorenije hitroumnogo Vobana / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2003-01-01

Prantsuse kindlusteehitajast Sebastien le Prestre de Vauban'ist, kelle loodud süsteemi arvatavasti kasutasid rootsi arhitektid E. Dahlberg ja P. von Essen Tallinna kindlustuste rekonstrueerimisel 17. sajandil. Mainitakse Tallinna kindlustuste maketti aastast 1686, mis on säilinud Stockholmis ja mille täpne koopia on Tallinna Linnamuuseumis

Levée en masse

DEFF Research Database (Denmark)

Galster, Kjeld

, and co-operates closely with allies and other partners in various far away trouble spots. Moreover, although modern equipment is expensive, personnel are even more so and, since no immediate threat is looming near national borders, the organisation is cut to the bone. Conscription is a matter of only...... follow the linguistic delimitations of the nation, and Germany is no longer perceived as a threat to national security, albeit that some see her influence through the EU as a menace to cultural values and national identity. Denmark has become an integral part of NATO and to a certain extent of the EU......, is unjust and deprives the system of its democratic legitimacy....

Strategic Studies Quarterly. Volume 7, Number 3, Fall 2013

Science.gov (United States)

2013-01-01

Data Processing One of the five tasks given Air Force ISR chief Lt Gen Larry James by Secretary Donley was to develop a roadmap for intelligence...34 7. McCullough, "Eye on Future ISR." 8. "Lt Gen Larry James: Air Force Will Combine Space, Cyber and Airborne ISR Capa- bilities," Inside Defense... Burrows , This New Ocean (New York: Random House, 1998) 191. 81. Paul B. Stares, The Militarization of Space (Ithaca, NY: Cornell University Press) 49. 82

2011 Integrated Warfare Systems Conference Held in Arlington, Virginia on December 6-7, 2011

Science.gov (United States)

2011-12-06

Kaplan IWS6EA 1E2111 M. Roberts IWS6ENG2 1E2031 Director Sensor Netting/Track Management D. Burrows , IWS6SN/TM, 1E2131 Brian Harris...Invention (Basic and Applied Science) ≈45% ≈12% Director of Transition 11 • FNC, PEOs, Industry • ManTech • SBIR 12 Dr. Larry Schuette...engagement. − We are a people-centric organization for better or for worse • How are we doing? 32 Contact Information Larry Schuette

Eslicarbazepine acetate as a replacement for levetiracetam in people with epilepsy developing behavioral adverse events.

Science.gov (United States)

Jalihal, Virupakshi; Shankar, Rohit; Henley, William; Parrett, Mary; Tittensor, Phil; McLean, Brendan N; Ahmed, Ammad; Sander, Josemir W

2018-03-01

Psychiatric and behavioral side effects (PBSEs) are a major cause of antiepileptic drug (AED) withdrawal. Levetiracetam (LEV) is a recognized first-line AED with good seizure outcomes but recognized with PBSEs. Eslicarbazepine (ESL) is considered to function similarly to an active metabolite of the commonly used carbamazepine (CBZ). Carbamazepine is used as psychotropic medication to assist in various psychiatric illnesses such as mood disorders, aggression, and anxiety. The aim was to evaluate the psychiatric profile of ESL in people who had LEV withdrawn due to PBSEs in routine clinical practice to see if ESL can be used as a possible alternative to LEV. A retrospective observational review was conducted in two UK epilepsy centers looking at all cases exposed to ESL since its licensing in 2010. The ESL group was all patients with treatment-resistant epilepsy who developed intolerable PBSEs to LEV, subsequently trialed on ESL. The ESL group was matched to a group who tolerated LEV without intolerable PBSEs. Psychiatric disorders were identified from case notes. The Hamilton Depression Scale (HAM-D) was used to outcome change in mood. Clinical diagnoses of a mental disorder were compared between groups using the Fisher's exact test. Group differences in HAM-D scores were assessed using the independent samples t-test (alpha=0.05). The total number of people with active epilepsy in the two centers was 2142 of whom 46 had been exposed to ESL. Twenty-six had previous exposure to LEV and had intolerable PBSEs who were matched to a person tolerating LEV. There was no statistical differences in the two groups for mental disorders including mood as measured by HAM-D (Chi-square test: p=0.28). The ESL was well tolerated and did not produce significant PBSEs in those who had PBSEs with LEV leading to withdrawal of the drug. Though numbers were small, the findings suggest that ESL could be a treatment option in those who develop PBSEs with LEV and possibly other AEDs

Transvaginal retropubic sling systems: efficacy and patient acceptability

Directory of Open Access Journals (Sweden)

Moldovan CP

2015-02-01

Full Text Available Christina P Moldovan,1 Michelle E Marinone,2 Andrea Staack3 1Department of Psychology, Loma Linda University, Loma Linda, California, United States of America; 2School of Medicine, Loma Linda University, Loma Linda, California, United States of America; 3Department of Urology, Loma Linda University Medical Center, Loma Linda, California, United States of America Abstract: Stress urinary incontinence is a common, disabling, and costly medical problem that affects approximately 50% of women with urinary incontinence. Suburethral retropubic slings have been developed as a minimally invasive and effective surgical option, and they have been used as a first-line treatment for stress urinary incontinence since 1995. However, complications including vaginal extrusion, erosion, pain, bleeding, infections, lower urinary tract symptoms, urinary retention, and incontinence have been reported with use of the slings. Several companies manufacture sling kits, and the sling kits vary with regard to the composition of the mesh and introducer needle. The aim of this review was to determine which sling kit was most effective for patients, had minimal reported side effects, and was best accepted by patients and surgeons. In a review of the literature, it was found that a total of 38 studies were published between 1995 and 2014 that reported on eight tension-free retropubic sling kits: SPARC, RetroArc, Align, Advantage, Lynx, Desara, Supris, and Gynecare TVT. The Gynecare TVT was the most cited sling kit; the second most cited was the SPARC. This review provides a summary of the studies that have examined positive and negative outcomes of the retropubic tension-free suburethral sling procedure using various sling kits. Overall, the results of the literature review indicated that data from comparisons of the available sling kits are insufficient to make an evidenced-based recommendation. Therefore, the decision regarding which sling kit is appropriate to use in

Comparative Study of Univariate Spectrophotometry and Multivariate Calibration for the Determination of Levamisole Hydrochloride and Closantel Sodium in a Binary Mixture.

Science.gov (United States)

Abdel-Aziz, Omar; Hussien, Emad M; El Kosasy, Amira M; Ahmed, Neven

2016-07-01

Six simple, accurate, reproducible, and selective derivative spectrophotometric and chemometric methods have been developed and validated for the determination of levamisole HCl (Lev) either alone or in combination with closantel sodium (Clo) in the pharmaceutical dosage form. Lev was determined by first-derivative, first-derivative ratio, and mean-centering methods by measuring the peak amplitude at 220.8, 243.8, and 210.4 nm, respectively. The methods were linear over the concentration range 2.0-10.0 μg/mL Lev. The methods exhibited a high accuracy, with recovery data within ±1.9% and RSD <1.3% (n = 9) for the determination of Lev in the presence of Clo. Fortunately, Lev showed no significant UV absorbance at 370.6 nm, which allowed the determination of Clo over the concentration range 16.0-80.0 μg/mL using zero-order spectra, with a high precision (RSD <1.5%, n = 9). Furthermore, principal component regression and partial least-squares with optimized parameters were used for the determination of Lev in the presence of Clo. The recovery was within ±1%, with RSD <1.0% (n = 9) and root mean square error of prediction ≤1.0. The proposed methods were validated according to the International Conference on Harmonization guidelines. The proposed methods were used in the determination of Lev and Clo in a binary mixture and a pharmaceutical formulation, with high accuracy and precision.

A Girl with Idiopathic Epilepsy Showing Forced Normalization after Levetiracetam Administration.

Science.gov (United States)

Kawakami, Yasuhiko; Okazaki, Tetsuya; Takase, Masato; Fujino, Osamu; Itoh, Yasuhiko

2015-01-01

Forced normalization has been reported in association with almost all anti-epileptic drugs. We report on a 9-year-old girl with idiopathic epilepsy who showed forced normalization after administration of levetiracetam (LEV). She initially presented with generalized tonic-clonic seizures when she was 4 years old. Diffuse sharp and slow wave complexes (SWCs) were observed on electroencephalography (EEG). We prescribed sodium valproate (VPA) and benzodiazepines, but the seizures and EEG findings worsened gradually. Although subsequent administration of LEV stopped the seizures, the patient became subject to episodes of rage and violent behavior. Forced normalization was confirmed by the disappearance of SWCs on EEG. We reduced the dose of LEV and tried in various ways to resolve the situation, but finally we had to abandon LEV. To the best of our knowledge, this is the first report of a patient with idiopathic epilepsy but without disabilities in everyday life showing forced normalization associated with LEV administration.

The role of the leading edge vortex in lift augmentation of steadily revolving wings: a change in perspective.

Science.gov (United States)

Nabawy, Mostafa R A; Crowther, William J

2017-07-01

The presence of a stable leading edge vortex (LEV) on steadily revolving wings increases the maximum lift coefficient that can be generated from the wing and its role is important to understanding natural flyers and flapping wing vehicles. In this paper, the role of LEV in lift augmentation is discussed under two hypotheses referred to as 'additional lift' and 'absence of stall'. The 'additional lift' hypothesis represents the traditional view. It presumes that an additional suction/circulation from the LEV increases the lift above that of a potential flow solution. This behaviour may be represented through either the 'Polhamus leading edge suction' model or the so-called 'trapped vortex' model. The 'absence of stall' hypothesis is a more recent contender that presumes that the LEV prevents stall at high angles of attack where flow separation would normally occur. This behaviour is represented through the so-called 'normal force' model. We show that all three models can be written in the form of the same potential flow kernel with modifiers to account for the presence of a LEV. The modelling is built on previous work on quasi-steady models for hovering wings such that model parameters are determined from first principles, which allows a fair comparison between the models themselves, and the models and experimental data. We show that the two models which directly include the LEV as a lift generating component are built on a physical picture that does not represent the available experimental data. The simpler 'normal force' model, which does not explicitly model the LEV, performs best against data in the literature. We conclude that under steady conditions the LEV as an 'absence of stall' model/mechanism is the most satisfying explanation for observed aerodynamic behaviour. © 2017 The Author(s).

Walking in the Woods: A Phenomenological Study of Online Communities of Practice and Army Mentoring

Science.gov (United States)

2015-04-01

Williams & Morris , 2009). This embrace of complexity will help drive junior officers to be more adaptive and willing to embrace uncertainty, an...Springer Verlag. Williams, A. P., & Morris , J. C. (2009). The Development of Theory-Driven Evaluation in the Military: Theory on the Front Line...US) Sent: Tuesday , November 25, 2014 7:35 AM To: Mallory, Linda Dr CIV USA USMA Subject: FW: USMA 15-12 Kimball Survey Request (UNCLASSIFIED) Linda

Three-Year Retention Rates of Levetiracetam, Topiramate, and Oxcarbazepine: A Retrospective Hospital-Based Study.

Science.gov (United States)

Sunwoo, Jun-Sang; Park, Byeong-Su; Ahn, Seon Jae; Hwang, Sungeun; Park, Chan-Young; Jun, Jin-Sun; Kim, Dong Wook; Lee, Soon-Tae; Jung, Keun-Hwa; Park, Kyung-Il; Chu, Kon; Jung, Ki-Young; Lee, Sang Kun

We evaluated and compared the 3-year retention rates of levetiracetam (LEV), topiramate (TPM), and oxcarbazepine (OXC) in patients with epilepsy in routine clinical practice. We retrospectively reviewed medical records of patients with epilepsy who were newly prescribed LEV, TPM, or OXC from 2006 to 2010. The retention rates were estimated by the Kaplan-Meier analysis, and independent risk factors for drug discontinuation were analyzed by the Cox regression method. A total of 588 patients were included: LEV (n = 345), TPM (n = 190), and OXC (n = 53). Among them, 82% had focal epilepsy, whereas 14.8% had generalized epilepsy. The 3-year retention rates for LEV, TPM, and OXC, were 81.2%, 78.3%, and 54.7%, respectively. Levetiracetam and TPM had equivalent retention rates, whereas patients remained on OXC for a significantly shorter amount of time (P effects leading to drug withdrawal of OXC (87.5%) was higher than that of LEV (34.4%, P < 0.001) and TPM (52.5%, P = 0.012). The current study suggested that LEV and TPM had comparable retention profiles in the long-term treatment for both focal and generalized epilepsy. Meanwhile, OXC therapy seemed to be relatively less useful because of its poor tolerability.

Microarray labeling extension values: laboratory signatures for Affymetrix GeneChips

Science.gov (United States)

Lee, Yun-Shien; Chen, Chun-Houh; Tsai, Chi-Neu; Tsai, Chia-Lung; Chao, Angel; Wang, Tzu-Hao

2009-01-01

Interlaboratory comparison of microarray data, even when using the same platform, imposes several challenges to scientists. RNA quality, RNA labeling efficiency, hybridization procedures and data-mining tools can all contribute variations in each laboratory. In Affymetrix GeneChips, about 11–20 different 25-mer oligonucleotides are used to measure the level of each transcript. Here, we report that ‘labeling extension values (LEVs)’, which are correlation coefficients between probe intensities and probe positions, are highly correlated with the gene expression levels (GEVs) on eukayotic Affymetrix microarray data. By analyzing LEVs and GEVs in the publicly available 2414 cel files of 20 Affymetrix microarray types covering 13 species, we found that correlations between LEVs and GEVs only exist in eukaryotic RNAs, but not in prokaryotic ones. Surprisingly, Affymetrix results of the same specimens that were analyzed in different laboratories could be clearly differentiated only by LEVs, leading to the identification of ‘laboratory signatures’. In the examined dataset, GSE10797, filtering out high-LEV genes did not compromise the discovery of biological processes that are constructed by differentially expressed genes. In conclusion, LEVs provide a new filtering parameter for microarray analysis of gene expression and it may improve the inter- and intralaboratory comparability of Affymetrix GeneChips data. PMID:19295132

Mature Results of a Prospective Randomized Trial Comparing 5-Flourouracil with Leucovorin to 5-Flourouracil with Levamisole as Adjuvant Therapy of Stage II and III Colorectal Cancer- The Israel Cooperative Oncology Group (ICOG Study

Directory of Open Access Journals (Sweden)

Arie Figer, Aviram Nissan, Adi Shani, Riva Borovick, Mariana Stiener, Mario Baras, Herbert R. Freund, Aaron Sulkes, Alexander Stojadinovic, Tamar Peretz

2011-01-01

Full Text Available Objective: Survival benefit with adjuvant therapy was shown in patients with Stage III colorectal cancer (CRC. This study evaluates long-term (10-year outcome in patients with CRC randomly assigned to adjuvant 5-Fluorouracil/Leucovorin (5FU+LV or 5-FU/Levamisole (5FU+LEV.Methods: Between 1990 and 1995, 398 patients with curatively resected Stage II-III CRC were randomly assigned to adjuvant 5FU+LV or 5FU+LEV for 12 months.Results: No difference was evident in 10-year relapse-free or overall survival between study groups. Grade III toxicity was similar between groups; however, neurotoxicity was significantly greater with 5FU+LEV (p=0.02 and gastrointestinal toxicity with 5FU+LV (p=0.03. Female patients treated with 5FU+LEV had improved overall survival.Conclusions: Adjuvant treatment of CRC is still based on leucovorin modulated fluorouracil. The long-term follow-up results of this trial indicate that the adjuvant treatment of Stage II-III CRC with 5FU+LV or 5FU+LEV is equally effective. The finding of improved survival in female subjects treated with 5FU+LEV warrants further study to determine if Levamisole is a better modulator of 5-FU than Leucovorin in this patient subset.

Metropolização, homicídios e segurança pública na área metropolitana de Brasília: o município de Águas Lindas de Goiás

Directory of Open Access Journals (Sweden)

Analía Soria Batista

Full Text Available Resumo Neste artigo se discute o quadro metropolitano dos homicídios em 2010 em um município do Entorno de Brasília, Águas Lindas de Goiás (GO. As externalidades negativas da metropolização de Brasília, em interface com a estrutura e organização da segurança pública e a fragilidade das ações da assistência social no município, esclarecem a dinâmica dos homicídios e os fatores estruturais que influenciam para a sua ocorrência. A pesquisa baseia-se em dados socioeconômicos secundários e em entrevistas realizadas junto aos atores da segurança pública e da assistência social. Os resultados apontam para a segregação socioespacial e a exclusão social no processo de urbanização do município, o alto grau de interação econômica e social deste último com o Distrito Federal, isto é, a polarização que o Distrito Federal exerce na oferta ao mercado de trabalho e de serviços básicos de educação e saúde. Neste quadro, e em face da alta taxa de homicídios no município, o artigo indica a necessidade de políticas cooperadas entre os diferentes entes da Federação envolvidos (União, estados, Distrito Federal e municípios na área econômica e social e das políticas de segurança pública.

V galereje Draakoni eksponirujetsja tvortshestvo Lva Vassiljeva

Index Scriptorium Estoniae

2006-01-01

Lev Vassiljevi viimaste aastate temperamaalide näitus "Variatsioon elementidest avaruses" Draakoni galeriis. Kunstnikust. Tuulas sündinud Lev Vassiljev on õppinud Tallinnas ERKIs, töötanud Tallinnas ja Moskvas

UPPER PLEISTOCENE SMALL MAMMAL FAUNA FROM SALNOVA QUARRY (SALTRIO-VARESE-NORTHWESTERN LOMBARDY: PALEOENVIRONMENTAL RECONSTRUCTION AND CHIONOMYS NIVALIS POPULATION STUDY

Directory of Open Access Journals (Sweden)

FABIO BONA

2011-07-01

Full Text Available The small mammals collection described in the present paper has been collected during three field small excavation at the Upper Pleistocene site of Cava Salnova (Saltrio - VA -. The collection consists of 501 determined remains of small mammals coming from all 17 stratigraphical levels and belonging at least to 26 species. Two 14C datings (AMS has been made on small mammals bones belonging to the lev. 1b: 1- 34315 ± 200 yr BP; 2- 35101± 250 yr BP. The interpretation of faunal data enables us to propose the following palaeoenvironmental framework: lower levels, lev. b and liv. c, are characterized by a cool weather with a high degree of plant cover. The deposition of lev. e to the lev. g coincided with an important reforestation occurred at the same time of the hottest Wurmian interpleniglacial. In lev. m, n, o, the snow vole, although rare, reappears. This may indicate the beginning of the climatic cooling, which is the prelude to the Last Glacial Maximum. 

Analyzing forensic evidence based on density with magnetic levitation.

Science.gov (United States)

Lockett, Matthew R; Mirica, Katherine A; Mace, Charles R; Blackledge, Robert D; Whitesides, George M

2013-01-01

This paper describes a method for determining the density of contact trace objects with magnetic levitation (MagLev). MagLev measurements accurately determine the density (± 0.0002 g/cm(3) ) of a diamagnetic object and are compatible with objects that are nonuniform in shape and size. The MagLev device (composed of two permanent magnets with like poles facing) and the method described provide a means of accurately determining the density of trace objects. This method is inexpensive, rapid, and verifiable and provides numerical values--independent of the specific apparatus or analyst--that correspond to the absolute density of the sample that may be entered into a searchable database. We discuss the feasibility of MagLev as a possible means of characterizing forensic-related evidence and demonstrate the ability of MagLev to (i) determine the density of samples of glitter and gunpowder, (ii) separate glitter particles of different densities, and (iii) determine the density of a glitter sample that was removed from a complex sample matrix. © 2012 American Academy of Forensic Sciences.

Hollandi Heineken võib Saksa õlletootja Krombacheri üle võtta / Katri Soe-Suren

Index Scriptorium Estoniae

Soe-Suren, Katri

2008-01-01

Financial Times Deutschland andmetel plaanib Hollandi Heinekeni kontsern Saksa õlletootja Krombacheri ülevõtmist, Heinekeni sunnib laienema USA päritolu Anheuser-Buschi ülevõtmine InBevi poolt juuli keskpaigas. Lisa

I chocolate you = maailm estetiseeritakse / Askur Alas

Index Scriptorium Estoniae

Alas, Askur, 1973-

2007-01-01

Vene-ameerika kunstniku ja uusmeedia teoreetiku Lev Manovich'i eluloolisi andmeid, tema tegevusest. Infotehniliste vahendite estetiseerimise trendist. Mobiiltelefonide disaini muutumisest. Lev Manovich viibis Tallinna ülikoolis interaktiivse meedia ja teadmuskeskkondade magistriprogrammi kutsel

Analyzing Forensic Evidence Based on Density with Magnetic Levitation

OpenAIRE

Lockett, Matthew; Mirica, Katherine A.; Mace, Charles R.; Blackledge, Robert D.; Whitesides, George M.

2013-01-01

This paper describes a method for determining the density of contact trace objects with magnetic levitation (MagLev). MagLev measurements accurately determine the density (±0.0002 g/cm3) of a diamagnetic object and are compatible with objects that are nonuniform in shape and size. The MagLev device (composed of two permanent magnets with like poles facing) and the method described provide a means of accurately determining the density of trace objects. This method is inexpensive, rapid, and ve...

Behavioral effects and somnolence due to levetiracetam versus oxcarbazepine - a retrospective comparison study of North Indian patients with refractory epilepsy.

Science.gov (United States)

Shukla, Garima; Gupta, Anupama; Agarwal, Priya; Poornima, Shivani

2016-11-01

Levetiracetam (LEV) is often chosen early in the treatment of refractory epilepsy; however, its adverse effects have largely been studied as part of clinical trials. Oxcarbazepine and valproate (VPA) are the other commonly used AEDs and, hence, serve as good comparators. This study was conducted to evaluate behavioral abnormalities and somnolence among patients with epilepsy being treated with LEV and/or OXC compared with those receiving VPA. Data of consecutive patients attending our intractable epilepsy clinic over a 2 1/2-year period were reviewed, and patients with at least one seizure a month, who had been initiated on either or a combination of LEV, VPA, or OXC, were included for analysis. Data regarding behavioral adverse effects, daytime somnolence (EDS), and weight changes were collected apart from those regarding any major effect necessitating dose reduction or discontinuation of the AED. Among a total of 445 patients screened, 292 (93 F, median age: 21years [range: 8-54]; 237 focal and 55 generalized epilepsy) fulfilled inclusion criteria. Median epilepsy duration was 11years. Levetiracetam had been introduced in 114 patients, VPA in 134, and OXC in 151 during the study period. Twenty-three were on LEV+OXC, 27 on LEV+VPA, and 33 on VPA+OXC. Behavioral disturbances (irritability, obsessive manifestations, aggressiveness, and frank psychosis) were observed in 43 patients; 23 on introduction of LEV (20.2%); LEV was discontinued in 10 (9%). Daytime somnolence was reported by 28 patients, 15 on OXC (10%); 8 received oral modafinil for the same, while none discontinued this AED. Only one patient on LEV and 3 on VPA reported EDS. Menstrual disturbances were reported by 9, weight gain by 3, and severe hair loss by 2 females on VPA. Behavioral disturbances with levetiracetam are common among patients with refractory epilepsy while somnolence is common with oxcarbazepine. Antiepileptic drugs should be selected with this in perspective. Copyright © 2016 Elsevier

Influence of parental socio-economic status on diet quality of European adolescents: results from the HELENA study.

Science.gov (United States)

Béghin, L; Dauchet, L; De Vriendt, Tineke; Cuenca-García, M; Manios, Y; Toti, E; Plada, M; Widhalm, K; Repasy, J; Huybrechts, I; Kersting, M; Moreno, L A; Dallongeville, J

2014-04-14

Diet quality is influenced by socio-economic and geographical factors. The present study sought to assess whether adolescents' diet quality is affected by their parents' socio-economic status and whether the relationship between these factors is similar in northern and southern Europe. Data collected in the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study in eight European countries were analysed. Dietary intake data were recorded via repeated 24 h recalls (using specifically developed HELENA Dietary Intake Assessment Tool software) and converted into an adolescent-specific Diet Quality Index (DQI-AM). Socio-economic status was estimated through parental educational level (Par-Educ-Lev) and parental occupation level (Par-Occ-Lev) as reported by the adolescents in a specific questionnaire. The DQI-AM data were then analysed as a function of Par-Educ-Lev and Par-Occ-Lev in northern European countries (Austria, Belgium, France, Germany and Sweden) and southern European countries (Greece, Italy and Spain). We studied a total of 1768 adolescents (age 14.7 (SD 1.3) years; percentage of girls: 52.8%; 1135 and 633 subjects from northern and southern Europe, respectively). On average, the DQI-AM score was higher in southern Europe than in northern Europe (69.1 (SD 0.1) v. 60.4 (SD 2.8), respectively; P < 0.001; Δ = 12.6%). The DQI was positively correlated with both paternal and maternal Par-Educ-Lev. However, this association was more pronounced in northern Europe than in southern Europe (P interaction = 0.004 for the mother and 0.06 for the father). The DQI was also positively correlated with Par-Occ-Lev (all P trends < 0.01), but this correlation was independent of the geographical area (P interaction = 0.51 for the mother and 0.50 for the father). In conclusion, Par-Educ-Lev and Par-Occ-Lev are associated with diet quality in adolescents in Europe. However, this association differs between northern Europe and southern Europe.

Meta-analysis of adjunctive levetiracetam in refractory partial sei

Directory of Open Access Journals (Sweden)

ZHANG Ying

2012-10-01

Full Text Available Objective To evaluate the effects and tolerability of adjunctive levetiracetam (LEV in refractory partial seizures. Methods Relevant research articles about randomized controlled trials of adjunctive LEV in refractory partial seizures from January 1998 to December 2010 were retrieved from Cochrane Library, MEDLINE, EMbase, Social Sciences Citation Index (SSCI, VIP, Chinese National Knowledge Infrastructure (CNKI database, China Biology Medicine (CBM. Two reviewers independently evaluated the quality of the included articles and abstracted the data. A Meta-analysis was conducted by using RevMan 5.0 software. Results According to the enrollment criteria, eleven prospective, randomized controlled clinical trials with a total of 1192 in LEV group and 789 in placebo group were finally selected. The reduction in three endpoints (a 50% or greater reduction of partial seizure frequency per week, a 75% or greater reduction of partial seizure frequency per week and seizure free was significant in LEV group than placebo group. There was no significance between LEV group and placebo group in the withdrawl rate (1000 mg/d: OR = 1.180, 95%CI: 0.690-2.010, P = 0.540; 2000 mg/d: OR = 1.530, 95%CI: 0.770-3.030, P = 0.230; 3000 mg/d: OR = 1.000, 95% CI: 0.620-1.600, P = 1.000. The following adverse events were associated with LEV: somnolence (OR = 1.720, 95%CI: 1.280-2.310, P = 0.000, dizziness (OR = 1.490, 95%CI: 1.000-2.220, P = 0.050, asthenia (OR = 1.670, 95%CI: 1.140-2.240, P = 0.008, nasopharyngitis (OR = 1.120, 95% CI: 0.710-1.760, P = 0.630, psychiatric and behavioral abnormalities (OR = 2.120, 95% CI: 1.370-3.280, P = 0.000. Conclusion LEV is effective and well tolerated when added to existing therapy in patients with refractory partial seizures compared with control drugs. Further studies are needed to identify the effects of monotherapy of LEV in partial seizures.

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

dicarbollide) anion and its derivatives. Vladimir Bregadze Igor Sivaev Irina Lobanova Olga Kazheva Grigorii Alexandrov Andrey Kravchenko Vladimir Starodub Lev Buravov Lev Titov Oleg Dyachenko. Volume 122 Issue 1 January 2010 pp 37-41 ...

A review of vagus nerve stimulation as a therapeutic intervention

Directory of Open Access Journals (Sweden)

Johnson RL

2018-05-01

Full Text Available Rhaya L Johnson,1 Christopher G Wilson1,2 1Lawrence D Longo MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University, Loma Linda, CA, USA; 2Department of Pediatrics, Loma Linda University, Loma Linda, CA, USA Abstract: In this review, we provide an overview of the US Food and Drug Administration (FDA-approved clinical uses of vagus nerve stimulation (VNS as well as information about the ongoing studies and preclinical research to expand the use of VNS to additional applications. VNS is currently FDA approved for therapeutic use in patients aged >12 years with drug-resistant epilepsy and depression. Recent studies of VNS in in vivo systems have shown that it has anti-inflammatory properties which has led to more preclinical research aimed at expanding VNS treatment across a wider range of inflammatory disorders. Although the signaling pathway and mechanism by which VNS affects inflammation remain unknown, VNS has shown promising results in treating chronic inflammatory disorders such as sepsis, lung injury, rheumatoid arthritis (RA, and diabetes. It is also being used to control pain in fibromyalgia and migraines. This new preclinical research shows that VNS bears the promise of being applied to a wider range of therapeutic applications. Keywords: vagus nerve stimulation, pediatrics, inflammation, peripheral nerve stimulation, autonomic circuits

Effectiveness of dust control methods for crystalline silica and respirable suspended particulate matter exposure during manual concrete surface grinding.

Science.gov (United States)

Akbar-Khanzadeh, Farhang; Milz, Sheryl A; Wagner, Cynthia D; Bisesi, Michael S; Ames, April L; Khuder, Sadik; Susi, Pam; Akbar-Khanzadeh, Mahboubeh

2010-12-01

Concrete grinding exposes workers to unacceptable levels of crystalline silica dust, known to cause diseases such as silicosis and possibly lung cancer. This study examined the influence of major factors of exposure and effectiveness of existing dust control methods by simulating field concrete grinding in an enclosed workplace laboratory. Air was monitored during 201 concrete grinding sessions while using a variety of grinders, accessories, and existing dust control methods, including general ventilation (GV), local exhaust ventilation (LEV), and wet grinding. Task-specific geometric mean (GM) of respirable crystalline silica dust concentrations (mg/m³ for LEV:HEPA-, LEV:Shop-vac-, wet-, and uncontrolled-grinding, while GV was off/on, were 0.17/0.09, 0.57/0.13, 1.11/0.44, and 23.1/6.80, respectively. Silica dust concentrations (mg/m³ using 100-125 mm (4-5 inch) and 180 mm (7 inch) grinding cups were 0.53/0.22 and 2.43/0.56, respectively. GM concentrations of silica dust were significantly lower for (1) GV on (66.0%) vs. off, and (2) LEV:HEPA- (99.0%), LEV:Shop-vac- (98.1%) or wet- (94.4%) vs. uncontrolled-grinding. Task-specific GM of respirable suspended particulate matter (RSP) concentrations (mg/m³ for LEV:HEPA-, LEV:Shop-vac-, wet-, and uncontrolled grinding, while GV was off/on, were 1.58/0.63, 7.20/1.15, 9.52/4.13, and 152/47.8, respectively. GM concentrations of RSP using 100-125 mm and 180 mm grinding cups were 4.78/1.62 and 22.2/5.06, respectively. GM concentrations of RSP were significantly lower for (1) GV on (70.2%) vs. off, and (2) LEV:HEPA- (98.9%), LEV:Shop-vac- (96.9%) or wet- (92.6%) vs. uncontrolled grinding. Silica dust and RSP were not significantly affected by (1) orientation of grinding surfaces (vertical vs. inclined); (2) water flow rates for wet grinding; (3) length of task-specific sampling time; or, (4) among cup sizes of 100, 115 or 125 mm. No combination of factors or control methods reduced an 8-hr exposure level to below the

Contribution of Biomass Burning to Carbonaceous Aerosols in Mexico City during may 2013

Science.gov (United States)

Tzompa Sosa, Z. A.; Sullivan, A.; Kreidenweis, S. M.

2014-12-01

The Mexico City Metropolitan Area (MCMA) is one of the largest megacities in the world with a population of 20 million people. Emissions transported from outside the basin, such as wildfires and agricultural burning, represent a potentially large contribution to air quality degradation. This study analyzed PM10 filter samples from six different stations located across the MCMA from May, 2013, which represented the month with the most reported fire counts in the region between 2002-2013. Two meteorological regimes were established considering the number of satellite derived fire counts, changes in predominant wind direction, ambient concentrations of CO, PM10 and PM2.5, and precipitation patterns inside MCMA. The filter samples were analyzed for biomass burning tracers including levoglucosan (LEV), water-soluble potassium (WSK+); and water-soluble organic carbon (WSOC). Results of these analyses show that LEV concentrations correlated positively with ambient concentrations of PM2.5 and PM10 (R2=0.61 and R2=0.46, respectively). Strong correlations were also found between WSOC and LEV (R2=0.94) and between WSK+ and LEV (R2=0.75). An average LEV/WSOC ratio of 0.0147 was estimated for Regime 1 and 0.0062 for Regime 2. Our LEV concentrations and LEV/WSOC ratios are consistent with results found during the MILAGRO campaign (March, 2006). To the best of our knowledge, only total potassium concentrations have been measured in aerosol samples from MCMA. Therefore, this is the first study in MCMA to measure ambient concentrations of WSK+. Analysis of gravimetric mass concentrations showed that PM2.5 accounted for 60% of the PM10 mass concentration with an estimated PM10/PM2.5 ratio of 1.68. Estimates from our laboratory filter sample characterization indicated that we measured 37% of the total PM10 mass concentration. The missing mass is most likely crustal material (soil or dust) and carbonaceous aerosols that were not segregated into WSOC fraction. Assuming that LEV is

Social enterprises in Denmark: Historical, contextual and conceptual aspects

DEFF Research Database (Denmark)

Andersen, Linda Lundgaard; Hulgård, Lars; Jacobsen, Gurli

Social enterprises in Denmark: Historical, contextual and conceptual aspectsLinda Lundgaard Andersen & Lars Hulgård, Center for Social Enterprise, Roskilde UniversityGurli Jakobsen, Copenhagen Business SchoolCOST Action (EMPOWER‐SE)Working Group 1, Lisbon 28. february & 1. march 2018......Social enterprises in Denmark: Historical, contextual and conceptual aspectsLinda Lundgaard Andersen & Lars Hulgård, Center for Social Enterprise, Roskilde UniversityGurli Jakobsen, Copenhagen Business SchoolCOST Action (EMPOWER‐SE)Working Group 1, Lisbon 28. february & 1. march 2018...

Noncontact orientation of objects in three-dimensional space using magnetic levitation.

Science.gov (United States)

Subramaniam, Anand Bala; Yang, Dian; Yu, Hai-Dong; Nemiroski, Alex; Tricard, Simon; Ellerbee, Audrey K; Soh, Siowling; Whitesides, George M

2014-09-09

This paper describes several noncontact methods of orienting objects in 3D space using Magnetic Levitation (MagLev). The methods use two permanent magnets arranged coaxially with like poles facing and a container containing a paramagnetic liquid in which the objects are suspended. Absent external forcing, objects levitating in the device adopt predictable static orientations; the orientation depends on the shape and distribution of mass within the objects. The orientation of objects of uniform density in the MagLev device shows a sharp geometry-dependent transition: an analytical theory rationalizes this transition and predicts the orientation of objects in the MagLev device. Manipulation of the orientation of the levitating objects in space is achieved in two ways: (i) by rotating and/or translating the MagLev device while the objects are suspended in the paramagnetic solution between the magnets; (ii) by moving a small external magnet close to the levitating objects while keeping the device stationary. Unlike mechanical agitation or robotic selection, orienting using MagLev is possible for objects having a range of different physical characteristics (e.g., different shapes, sizes, and mechanical properties from hard polymers to gels and fluids). MagLev thus has the potential to be useful for sorting and positioning components in 3D space, orienting objects for assembly, constructing noncontact devices, and assembling objects composed of soft materials such as hydrogels, elastomers, and jammed granular media.

Magnetic levitation/suspension system by high-temperature superconducting materials

International Nuclear Information System (INIS)

Chen, I.; Hsu, J.; Jamn, G.; Lin, C.E.; Wu, M.K.

1997-01-01

Recently, with the advance of materials processing techniques, such as top-seeding and melt-texturing (TSMT) method, very large single-grained Y-Ba-Cu-O (YBCO) samples up to several centimeters in diameter can be produced. Each sample is capable of levitating over kilograms of weight. A HTS magnetic levitation (MagLev) transportation prototype has been constructed at National Cheng-Kung University (NCKU) to validate the concept of HTS-MagLev system based on Meissner effect. This HTS-MagLev is an inherent stable levitation system, unlike traditional MagLev system that requires sensors and feedback circuits to dynamically adjust its unstable levitation position. In this report, the results of various magnetic levitation parameters, such as different permanent magnet configurations, relative levitation stability, levitation force, etc., as well as magnetic field intensity and distribution will be discussed. copyright 1997 American Institute of Physics

Pamjatnik istorii i iskusstva / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2004-01-01

Tallinna Toomkiriku hoonest ja seal asuvatest kunstiväärtustest: Christian Ackermanni teostatud altar ja kantsel, Arent Passeri loodud P. De la Gardie sarkofaag ja epitaaf, S. Greighi hauamonument, F. v. Tiesenhauseni mälestusobelisk

Mir na Artilleriskoi ulitse / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2006-01-01

Tallinna Suurtüki tänava ajaloost ja tänapäevast (Alarm Strasse, Stückgasse, Pushetshnaja, Pargi). Ka tänavaga piirneva linnamüüri ajaloost. Kotzebuede perekonnast. Kotzebue nime kannab tänav Tallinnas

gene polymorphism and its serum lev

Indian Academy of Sciences (India)

Navya

polymorphisms and its serum level with the risk of MetS as well as their ... population for quantifying insulin resistance and β-cell function (Matthews et al. 1985). .... of IL-10 -819 C >T gene polymorphism (Co-dominant model) was significantly.

Tsherez veka v sovremennost / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2002-01-01

Tallinnas Pikk tän. 19 asuvast hoonest: ehitamine, müük vene saatkonna tarbeks (1921), vene saatkonna ruumide kirjeldus. Seal on Kaire Tali valmistatud vene lipu värvides vaip ja Andrei Lobanovi vitraaž

gene polymorphism and its serum lev

Indian Academy of Sciences (India)

Navya

Association of Interleukin-10 (-1082 A>G, -819 C >T and -592 C >A) gene polymorphism and its ... Th2 induced component of anti-β cell immunity is mediated principally by IL-10 (Lee et al. ..... promoter polymorphisms influence the clinical outcome of diffuse large B-cell lymphoma. ... Bone Marrow Transplant 36, 1089-1095.

"Fall, divnõi Fall..." / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2001-01-01

Keila-Joa mõisa ajaloost fotograaf Faivi Kljutshiku fotode põhjal. Loss (1833) - arhitekt Aleksei Lvov, uue lossi arhitekt Hans (Andrei) Stackenschneider Peterburist, kiviraidur Johann Gottfried Exner

Ognjami mne sverknul vokzal... / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2006-01-01

Kunstimetseenidest Venemaal. Neist parun Alexander Stieglitzi elu oli seotud Narvaga. Tema asutatud A. Stieglitzi kunsttööstuskoolis Peterburis õppis 15 eesti kunstnikku. Raudtee rajamisest Eestis ja Reveli vaksalihoone ning seda ümbritsevate alade ajaloost

Tshto god grjadushtshii nam... / Lev Golub

Index Scriptorium Estoniae

Golub, Lev

2008-01-01

Autor analüüsib Eesti majanduse hetkeolukorda ja tulevikku. Ta leiab, et meie valitsus ja peaminister ei näe riigi majanduses mingeid erilisi probleeme ja raskusi, räägitakse nn. pehmest maandumisest

Moroz i rozõ / Lev Livshits

Index Scriptorium Estoniae

Лившиц, Лев, 1924-2013

2006-01-01

Ain Järvega Kadrioru pargist. Kadrioru Lastepargi tekkimise ajaloost ja uue Lastepargi rajamisest. Ehitatakse uus Lastemuuseumi hoone kuhu kolib Kotzebue tänavalt Tallinna Nukumuuseum. Nukumuuseumist ja muuseumidest Kadriorus, ka KUMU hoonest

Local exhaust ventilation for the control of welding fumes in the construction industry--a literature review.

Science.gov (United States)

Flynn, Michael R; Susi, Pam

2012-08-01

Arc welding is a common unit operation in the construction industry, where frequent changes in location and welding position make it more difficult to control fume exposures than in industries where fixed locations are the norm. Welders may be exposed to a variety of toxic airborne contaminants including manganese (Mn) and hexavalent chromium (CrVI). Local exhaust ventilation (LEV) is a well-known engineering control for welding fumes but has not been adopted widely in the construction industry. This literature review presents data on the performance of a variety of LEV systems for welding fume control from the construction (five references), shipyard (five references), and other industries. The studies indicate that LEV can reduce fume exposures to total particulate, Mn, and CrVI to levels below currently relevant standards. Field studies suggest that 40-50% or more reduction in exposure is possible with portable or fixed LEV systems relative to natural ventilation but that correct positioning of the hood and adequate exhaust flow rates are essential. Successful implementation of extraction guns for gas metal arc welding (GMAW) and flux core arc welding has been demonstrated, indicating that a successful balance between extraction airflow and shielding gas requirements is possible. Work practices are an important part of achieving successful control of fume exposures; in particular, positioning the hood close to the arc, checking exhaust flow rates, and avoiding the plume. Further research is needed on hood size effects for controlling welding fume with portable LEV systems and identifying and overcoming barriers to LEV use in construction.

The leading-edge vortex of swift wing-shaped delta wings.

Science.gov (United States)

Muir, Rowan Eveline; Arredondo-Galeana, Abel; Viola, Ignazio Maria

2017-08-01

Recent investigations on the aerodynamics of natural fliers have illuminated the significance of the leading-edge vortex (LEV) for lift generation in a variety of flight conditions. A well-documented example of an LEV is that generated by aircraft with highly swept, delta-shaped wings. While the wing aerodynamics of a manoeuvring aircraft, a bird gliding and a bird in flapping flight vary significantly, it is believed that this existing knowledge can serve to add understanding to the complex aerodynamics of natural fliers. In this investigation, a model non-slender delta-shaped wing with a sharp leading edge is tested at low Reynolds number, along with a delta wing of the same design, but with a modified trailing edge inspired by the wing of a common swift Apus apus . The effect of the tapering swift wing on LEV development and stability is compared with the flow structure over the unmodified delta wing model through particle image velocimetry. For the first time, a leading-edge vortex system consisting of a dual or triple LEV is recorded on a swift wing-shaped delta wing, where such a system is found across all tested conditions. It is shown that the spanwise location of LEV breakdown is governed by the local chord rather than Reynolds number or angle of attack. These findings suggest that the trailing-edge geometry of the swift wing alone does not prevent the common swift from generating an LEV system comparable with that of a delta-shaped wing.

Monotherapy for partial epilepsy: focus on levetiracetam

Directory of Open Access Journals (Sweden)

Antonio Gambardella

2008-03-01

Full Text Available Antonio Gambardella1,2, Angelo Labate1,2, Eleonora Colosimo1, Roberta Ambrosio1, Aldo Quattrone1,21Institute of Neurology, University Magna Græcia, Catanzaro, Italy; 2Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, ItalyAbstract: Levetiracetam (LEV, the S-enantiomer of alpha-ethyl-2-oxo-1-pyrollidine acetamide, is a recently licensed antiepileptic drug (AED for adjunctive therapy of partial seizures. Its mechanism of action is uncertain but it exhibits a unique profile of anticonvulsant activity in models of chronic epilepsy. Five randomized, double-blind, placebo-controlled trials enrolling adult or pediatric patients with refractory partial epilepsy have demonstrated the efficacy of LEV as adjunctive therapy, with a responder rate (≥50% reduction in seizure frequency of 28%–45%. Long-term efficacy studies suggest retention rates of 60% after one year, with 13% of patients seizure-free for 6 months of the study and 8% seizure-free for 1 year. More recent studies illustrated successful conversion to monotherapy in patients with refractory epilepsy, and its effectiveness as a single agent in partial epilepsy. LEV has also efficacy in generalized epilepsies. Adverse effects of LEV, including somnolence, lethargy, and dizziness, are generally mild and their occurrence rate seems to be not significantly different from that observed in placebo groups. LEV also has no clinically significant pharmacokinetic interactions with other AEDs, or with commonly prescribed medications. The combination of effective antiepileptic properties with a relatively mild adverse effect profile makes LEV an attractive therapy for partial seizures.Keywords: levetiracetam, partial epilepsy, antiepileptic drugs

Rotational accelerations stabilize leading edge vortices on revolving fly wings

NARCIS (Netherlands)

Lentink, D.; Dickinson, M.H.

2009-01-01

The aerodynamic performance of hovering insects is largely explained by the presence of a stably attached leading edge vortex (LEV) on top of their wings. Although LEVs have been visualized on real, physically modeled, and simulated insects, the physical mechanisms responsible for their stability

Leading-edge flow criticality as a governing factor in leading-edge vortex initiation in unsteady airfoil flows

Science.gov (United States)

Ramesh, Kiran; Granlund, Kenneth; Ol, Michael V.; Gopalarathnam, Ashok; Edwards, Jack R.

2018-04-01

A leading-edge suction parameter (LESP) that is derived from potential flow theory as a measure of suction at the airfoil leading edge is used to study initiation of leading-edge vortex (LEV) formation in this article. The LESP hypothesis is presented, which states that LEV formation in unsteady flows for specified airfoil shape and Reynolds number occurs at a critical constant value of LESP, regardless of motion kinematics. This hypothesis is tested and validated against a large set of data from CFD and experimental studies of flows with LEV formation. The hypothesis is seen to hold except in cases with slow-rate kinematics which evince significant trailing-edge separation (which refers here to separation leading to reversed flow on the aft portion of the upper surface), thereby establishing the envelope of validity. The implication is that the critical LESP value for an airfoil-Reynolds number combination may be calibrated using CFD or experiment for just one motion and then employed to predict LEV initiation for any other (fast-rate) motion. It is also shown that the LESP concept may be used in an inverse mode to generate motion kinematics that would either prevent LEV formation or trigger the same as per aerodynamic requirements.

Tria Pharmaceuticals in the Baltics

DEFF Research Database (Denmark)

Kratochvil, Renate; Nell, Phillip C.

2016-01-01

Linda, a management consultant, had to solve a tricky problem regarding difficulties with the 'Baltic region subsidiary' of a global pharmaceutical company. She was hired by their Regional Headquarters (RHQ) for Central and Eastern Europe to disentangle this multifaceted challenge (eg sales down...... on the topic were the cultural misunderstandings between the employees of the various countries, or the company’s outdated products. Linda was challenged to, first, get a clear and comprehensive picture of the situation, and, second, propose a well-conceived solution to the RHQ. This case is written as a two...

Flow structure and vorticity transport on a plunging wing

Science.gov (United States)

Eslam Panah, Azar

The structure and dynamics of the flow field created by a plunging flat plate airfoil are investigated at a chord Reynolds number of 10,000 while varying plunge amplitude and Strouhal number. Digital particle image velocimetry measurements are used to characterize the shedding patterns and the interactions between the leading and trailing edge vortex structures (LEV and TEV), resulting in the development of a wake classification system based on the nature and timing of interactions between the leading- and trailing-edge vortices. The convection speed of the LEV and its resulting interaction with the TEV is primarily dependent on reduced frequency; however, at Strouhal numbers above approximately 0.4, a significant influence of Strouhal number (or plunge amplitude) is observed in which LEV convection is retarded, and the contribution of the LEV to the wake is diminished. It is shown that this effect is caused by an enhanced interaction between the LEV and the airfoil surface, due to a significant increase in the strength of the vortices in this Strouhal number range, for all plunge amplitudes investigated. Comparison with low-Reynolds-number studies of plunging airfoil aerodynamics reveals a high degree of consistency and suggests applicability of the classification system beyond the range examined in the present work. Some important differences are also observed. The three-dimensional flow field was characterized for a plunging two-dimensional flat-plate airfoil using three-dimensional reconstructions of planar PIV data. Whereas the phase-averaged description of the flow field shows the secondary vortex penetrating the leading-edge shear layer to terminate LEV formation on the airfoil, time-resolved, instantaneous PIV measurements show a continuous and growing entrainment of secondary vorticity into the shear layer and LEV. A planar control volume analysis on the airfoil indicated that the generation of secondary vorticity produced approximately one half the

Safety and pharmacokinetics of intravenous levetiracetam infusion as add-on in status epilepticus

NARCIS (Netherlands)

Uges, Joris W F; van Huizen, Marc D; Engelsman, Jeroen; Wilms, Erik B; Touw, Daniel J; Peeters, Els; Vecht, Charles J

PURPOSE: To evaluate the feasibility and safety of intravenous (iv) levetiracetam (LEV) added to the standard therapeutic regimen in adults with status epilepticus (SE), and as secondary objective to assess a population pharmacokinetic (PK) model for ivLEV in patients with SE. METHODS: In 12 adults

Synthesis of deuterium and tritium labelled m-aminolevamisole and levamisole. [Antiparasitic agents

Energy Technology Data Exchange (ETDEWEB)

Sangster, N.C. (Sydney Univ. (Australia). Dept. of Veterinary Pathology); Lacey, E. (Commonwealth Scientific and Industrial Research Organization, Glebe (Australia). McMaster Lab.); Than, C.; Long, M.A. (New South Wales Univ., Kensington (Australia). School of Chemistry)

1989-09-01

Levamisole (LEV) is a widely used anti-parasitic agent. In order to characterise the biochemical pharmacology of LEF in parasitic nematodes, ({sup 3}H)LEV and a more active analogue ({sup 3}H)m-aminolevamisole (MAL) have been prepared. Labelling was accomplished by tritiated water exchange of MAL under acid conditions. Multiple site labelling was achieved in the positions ortho and para to the amino group of MAL. Tritiation of MAL HCl in ({sup 3}H){sub 2}O was achieved at 103{sup o}C for 23 h. Crude ({sup 3}H)MAL was diazotised and deaminated to effect the synthesis of ({sup 3}H)LEV. Products of both reactions were purified by preparative h.p.l.c. and characterised by h.p.l.c., t.l.c. and mass spectrometry. (Radiochemical yield was about 15% and purity >90%.) Specific activities of 39 Ci/mmol for ({sup 3}H)MAL and 37 Ci/mmol for ({sup 3}H)LEV were obtained. (author).

Criteria and air-toxic emissions from in-use automobiles in the National Low-Emission Vehicle program.

Science.gov (United States)

Baldauf, Rich W; Gabele, Pete; Crews, William; Snow, Richard; Cook, J Rich

2005-09-01

The U.S. Environmental Protection Agency (EPA) implemented a program to identify tailpipe emissions of criteria and air-toxic contaminants from in-use, light-duty low-emission vehicles (LEVs). EPA recruited 25 LEVs in 2002 and measured emissions on a chassis dynamometer using the cold-start urban dynamometer driving schedule of the Federal Test Procedure. The emissions measured included regulated pollutants, particulate matter, speciated hydrocarbon compounds, and carbonyl compounds. The results provided a comparison of emissions from real-world LEVs with emission standards for criteria and air-toxic compounds. Emission measurements indicated that a portion of the in-use fleet tested exceeded standards for the criteria gases. Real-time regulated and speciated hydrocarbon measurements demonstrated that the majority of emissions occurred during the initial phases of the cold-start portion of the urban dynamometer driving schedule. Overall, the study provided updated emission factor data for real-world, in-use operation of LEVs for improved emissions modeling and mobile source inventory development.

Magnetic Levitation To Characterize the Kinetics of Free-Radical Polymerization.

Science.gov (United States)

Ge, Shencheng; Semenov, Sergey N; Nagarkar, Amit A; Milette, Jonathan; Christodouleas, Dionysios C; Yuan, Li; Whitesides, George M

2017-12-27

This work describes the development of magnetic levitation (MagLev) to characterize the kinetics of free-radical polymerization of water-insoluble, low-molecular-weight monomers that show a large change in density upon polymerization. Maglev measures density, and certain classes of monomers show a large change in density when monomers covalently join in polymer chains. MagLev characterized both the thermal polymerization of methacrylate-based monomers and the photopolymerization of methyl methacrylate and made it possible to determine the orders of reaction and the Arrhenius activation energy of polymerization. MagLev also made it possible to monitor polymerization in the presence of solids (aramid fibers, and carbon fibers, and glass fibers). MagLev offers a new analytical technique to materials and polymer scientists that complements other methods (even those based on density, such as dilatometry), and will be useful in investigating polymerizations, evaluating inhibition of polymerizations, and studying polymerization in the presence of included solid materials (e.g., for composite materials).

Density determination of nail polishes and paint chips using magnetic levitation

Science.gov (United States)

Huang, Peggy P.

Trace evidence is often small, easily overlooked, and difficult to analyze. This study describes a nondestructive method to separate and accurately determine the density of trace evidence samples, specifically nail polish and paint chip using magnetic levitation (MagLev). By determining the levitation height of each sample in the MagLev device, the density of the sample is back extrapolated using a standard density bead linear regression line. The results show that MagLev distinguishes among eight clear nail polishes, including samples from the same manufacturer; separates select colored nail polishes from the same manufacturer; can determine the density range of household paint chips; and shows limited levitation for unknown paint chips. MagLev provides a simple, affordable, and nondestructive means of determining density. The addition of co-solutes to the paramagnetic solution to expand the density range may result in greater discriminatory power and separation and lead to further applications of this technique.

The effect of aspect ratio on the leading-edge vortex over an insect-like flapping wing.

Science.gov (United States)

Phillips, Nathan; Knowles, Kevin; Bomphrey, Richard J

2015-10-09

Insect wing shapes are diverse and a renowned source of inspiration for the new generation of autonomous flapping vehicles, yet the aerodynamic consequences of varying geometry is not well understood. One of the most defining and aerodynamically significant measures of wing shape is the aspect ratio, defined as the ratio of wing length (R) to mean wing chord (c). We investigated the impact of aspect ratio, AR, on the induced flow field around a flapping wing using a robotic device. Rigid rectangular wings ranging from AR = 1.5 to 7.5 were flapped with insect-like kinematics in air with a constant Reynolds number (Re) of 1400, and a dimensionless stroke amplitude of 6.5c (number of chords traversed by the wingtip). Pseudo-volumetric, ensemble-averaged, flow fields around the wings were captured using particle image velocimetry at 11 instances throughout simulated downstrokes. Results confirmed the presence of a high-lift, separated flow field with a leading-edge vortex (LEV), and revealed that the conical, primary LEV grows in size and strength with increasing AR. In each case, the LEV had an arch-shaped axis with its outboard end originating from a focus-sink singularity on the wing surface near the tip. LEV detachment was observed for AR > 1.5 around mid-stroke at ~70% span, and initiated sooner over higher aspect ratio wings. At AR > 3 the larger, stronger vortex persisted under the wing surface well into the next half-stroke leading to a reduction in lift. Circulatory lift attributable to the LEV increased with AR up to AR = 6. Higher aspect ratios generated proportionally less lift distally because of LEV breakdown, and also less lift closer to the wing root due to the previous LEV's continuing presence under the wing. In nature, insect wings go no higher than AR ~ 5, likely in part due to architectural and physiological constraints but also because of the reducing aerodynamic benefits of high AR wings.

Tobacco control policy: strategies, successes, and setbacks

National Research Council Canada - National Science Library

Brigden, Linda Waverley; De Beyer, Joy

2003-01-01

... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Joy de Beyer and Linda Waverley Brigden Why These Six Countries?. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 What Factors Made...

75 FR 35765 - Proposed Information Collection; Comment Request; BroadbandMatch Web Site Tool

Science.gov (United States)

2010-06-23

... infrastructure, public computer centers and sustainable broadband adoption projects. NTIA Administrator Larry E... the White House's Open Government Initiative that seeks to promote transparency, openness and...

Carl Linné sidemed Baltimaadega / Linda Kongo

Index Scriptorium Estoniae

Kongo, Linda, 1929-

2007-01-01

Carl Linné sidemed Baltimaadega on loonud tema õpilased ja õpilaste õpilased, kes siirdusid kuulama tema loenguid Uppsala Ülikoolis. Mitmed Baltimaadelt pärit loodusteadlased täiendasid end Linné õpilase Johann Andreas Murray juures. Tartu Ülikooli raamatukogus on hoiul üks Linné kiri

Juhan Liiv / Hella Wuolijoki ; tlk. Linda Viiding

Index Scriptorium Estoniae

Wuolijoki, Hella, 1886-1954

2000-01-01

Esmatrükk: Wuolijoki, H. Koulutyttönä Tartossa vuosina 1901-1904. Helsinki, 1945 ; Wuolijoki, H. Koulutyttönä Tartossa vuosina 1901-1904. Helsinki, 1972. Tõlge: Wuolijoki, H. Koolitüdrukuna Tartus aastail 1901-1904. Tln., 1986 ; Wuolijoki, H. Koolitüdrukuna Tartus aastail 1901-1904. Tln., 1995

Viljandis tuleb imeline kohtumine / Linda Järve

Index Scriptorium Estoniae

Järve, Linda, 1946-

2001-01-01

8.-22. juulinì01 toimub Eestis 10. Euroopa Laste Teatrikohtumine (EDERED - European Drama Encounter), mis toob kohale 180 last koos juhendajatega 18 riigist. Samal ajal on koos ka EDERED-i peaassamblee. Kahenädalase, peamiselt Viljandis aset leidva kohtumise korraldavad Eesti Harrastusteatrite Liit, haridusministeerium ja Viljandi linnavalitsus. EDERED loodi 1985. a, pärast 4 aastat varem toimunud esimest laste teatrikohtumist, kus osalesid 12-14-aastased lapsed. Hiljem lisandusid EDERED-i ürituste hulka ka noorte teatrikohtumised, kus osalejad on 16-20-aastased. EDERED-i kohtumistel kasutatakse mitmesuguseid teatriõpetuse meetodeid, toimub loov koostöö laste ja õpetajate vahel

Effects of traveling waves on flow separation and turbulence

Science.gov (United States)

Akbarzadeh, Amir Mahdi; Borazjani, Iman; scientific computing; biofluids laboratory Team

2017-11-01

Stable leading edge vortex (LEV) is observed in many flying, hovering and also some aquatic creatures. However, the LEV stability in aquatic animal, in contrast to hovering ones, is not well understood. Here, we study the flow over an inclined plate with an undulatory motion inspired from aquatic swimmers using our immersed boundary, large-eddy simulations (LES). The angle of attack is five degrees and Reynolds number (Re) is 20,000. The undulation is a traveling wave, which has a constant amplitude of 0.01 with respect to chord length and a different wavelength and Strouhal number (St =fA/U, f: frequency, A: amplitude, and U: free stream velocity) for each case. Over a fixed plate the LEV becomes unstable as it reaches the trailing edge and sheds to the wake, whereas over the undulating plate with St =0.2 the LEV becomes stable. The visualization of time average results shows there is a favorable pressure gradient along the tangential direction in cases the LEV becomes stable, which we explain analytically by showing the correlation between the average pressure gradient, St, and wavelength. Finally, the effects of undulatory moving walls of a channel flow on the turbulent statistics is shown. This work was partly supported by the National Science Foundation (NSF) CAREER Grant CBET 1453982, and the Center of Computational Research (CCR) of University at Buffalo.

Resting-state fMRI revealed different brain activities responding to valproic acid and levetiracetam in benign epilepsy with central-temporal spikes

Energy Technology Data Exchange (ETDEWEB)

Zhang, Qirui; Zhang, Zhiqiang; Xu, Qiang; Wu, Han; Li, Zhipeng; Lu, Guangming [Nanjing University School of Medicine, Department of Medical Imaging, Jinling Hospital, Nanjing (China); Yang, Fang; Li, Qian [Nanjing University School of Medicine, Department of Neurology, Jinling Hospital, Nanjing (China); Hu, Zheng [Nanjing Children' s Hospital, Department of Neurology, Nanjing (China); Dante, Mantini [Faculty of Kinesiology and Rehabilitation Sciences, KU Leuven (Belgium); Li, Kai [Suzhou University, Laboratory of Molecular Medicine, Suzhou (China)

2017-05-15

Our aim was to investigate regional difference in brain activities in response to antiepileptic drug (AED) medications in benign epilepsy with central-temporal spikes (BECTS) using resting-state functional magnetic resonance imaging (fMRI). Fifty-seven patients with BECTS underwent resting-state fMRI scans after receiving either valproic acid (VPA) (n = 15), levetiracetam (LEV) (n = 21), or no medication (n = 21). fMRI regional homogeneity (ReHo) parameter among the three groups of patients were compared and were correlated with total doses of AED in the two medicated groups. Compared with patients on no-medication, patients receiving either VPA or LEV showed decreased ReHo in the central-temporal region, frontal cortex, and thalamus. In particular, the VPA group showed greater ReHo decrease in the thalamus and milder in cortices and caudate heads compared with the LEV group. In addition, the VPA group demonstrated a negative correlation between ReHo values in the central-temporal region and medication dose. Both VPA and LEV inhibit resting-state neural activity in the central-temporal region, which is the main epileptogenic focus of BECTS. VPA reduced brain activity in the cortical epileptogenic regions and thalamus evenly, whereas LEV reduced brain activity predominantly in the cortices. Interestingly, VPA showed a cumulative effect on inhibiting brain activity in the epileptogenic regions in BECTS. (orig.)

The leading-edge vortex of swift-wing shaped delta wings

Science.gov (United States)

Muir, Rowan; Arredondo-Galeana, Abel; Viola, Ignazio Maria

2017-11-01

Recent investigations on the aerodynamics of natural fliers have illuminated the significance of the Leading-Edge Vortex (LEV) for lift generation in a variety of flight conditions. In this investigation, a model non-slender delta shaped wing with a sharp leading-edge is tested at low Reynolds Number, along with a delta wing of the same design, but with a modified trailing edge inspired by the wing of a common swift Apus apus. The effect of the tapering swift wing on LEV development and stability is compared with the flow structure over the un-modified delta wing model through particle image velocimetry. For the first time, a leading-edge vortex system consisting of a dual or triple LEV is recorded on a swift-wing shaped delta wing, where such a system is found across all tested conditions. It is shown that the spanwise location of LEV breakdown is governed by the local chord rather than Reynolds Number or angle of attack. These findings suggest that the trailing-edge geometry of the swift wing alone does not prevent the common swift from generating an LEV system comparable with that of a delta shaped wing. This work received funding from the Engineering and Physical Sciences Research Council [EP/M506515/1] and the Consejo Nacional de Ciencia y Tecnología (CONACYT).

Resting-state fMRI revealed different brain activities responding to valproic acid and levetiracetam in benign epilepsy with central-temporal spikes

International Nuclear Information System (INIS)

Zhang, Qirui; Zhang, Zhiqiang; Xu, Qiang; Wu, Han; Li, Zhipeng; Lu, Guangming; Yang, Fang; Li, Qian; Hu, Zheng; Dante, Mantini; Li, Kai

2017-01-01

Our aim was to investigate regional difference in brain activities in response to antiepileptic drug (AED) medications in benign epilepsy with central-temporal spikes (BECTS) using resting-state functional magnetic resonance imaging (fMRI). Fifty-seven patients with BECTS underwent resting-state fMRI scans after receiving either valproic acid (VPA) (n = 15), levetiracetam (LEV) (n = 21), or no medication (n = 21). fMRI regional homogeneity (ReHo) parameter among the three groups of patients were compared and were correlated with total doses of AED in the two medicated groups. Compared with patients on no-medication, patients receiving either VPA or LEV showed decreased ReHo in the central-temporal region, frontal cortex, and thalamus. In particular, the VPA group showed greater ReHo decrease in the thalamus and milder in cortices and caudate heads compared with the LEV group. In addition, the VPA group demonstrated a negative correlation between ReHo values in the central-temporal region and medication dose. Both VPA and LEV inhibit resting-state neural activity in the central-temporal region, which is the main epileptogenic focus of BECTS. VPA reduced brain activity in the cortical epileptogenic regions and thalamus evenly, whereas LEV reduced brain activity predominantly in the cortices. Interestingly, VPA showed a cumulative effect on inhibiting brain activity in the epileptogenic regions in BECTS. (orig.)

A prospective study of levetiracetam efficacy in epileptic syndromes with continuous spikes-waves during slow sleep

DEFF Research Database (Denmark)

Atkins, Mary; Nikanorova, Marina

2011-01-01

To evaluate the add-on effect of levetiracetam (LEV) treatment on the EEG and clinical status of children with continuous spikes-waves during slow sleep (CSWS).......To evaluate the add-on effect of levetiracetam (LEV) treatment on the EEG and clinical status of children with continuous spikes-waves during slow sleep (CSWS)....

Blind Grid Scoring Record No. 290

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Blind Grid Scoring Record No. 293

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George; Archiable, Robert; Fling, Rick; McClung, Christina

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Blind Grid. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record Number 312

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Archiable, Robert; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Scoring Committee...

Standardized UXO Demonstration Site Blind Grid Scoring Record No. 690

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Archiable, Robert; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Scoring Committee...

Standardized UXO Technology Demonstration Site, Blind Grid Scoring Record No. 257

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Robitaille, George; Boutin, Matthew; Fling, Rick; McClung, Christina

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record No. 252

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Boutin, Matthew; Fling, Rick; McClung, Christina

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record Number 691

National Research Council Canada - National Science Library

Overbay, Jr., Larry; Watts, Kimberly; Fling, Rick; McClung, Christina; Banta, Matthew

2006-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site blind grid. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Blind Grid Scoring Record No. 237

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Robitaille, George; Boutin, Matthew; Fling, Rick; McClung, Christina

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record No. 764

National Research Council Canada - National Science Library

Overbay, Larry; Watts, Kimberly

2006-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record No. 690

National Research Council Canada - National Science Library

Overbay, Larry

2005-01-01

...) utilizing the YPC Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Scoring Committee...

Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 426

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Boutin, Matthew; Archiable, Robert; Fling, Rick; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 657

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 673 (Naval Research Laboratories)

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the APG standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinate by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Open Field Scoring Record No. 298

National Research Council Canada - National Science Library

Overbay, Jr., Larry; Robitaille, George; Fling, Rick; McClung, Christina

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 492 (Shaw Environmental, Inc.)

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record No. 442

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Boutin, Matthew; Archiable, Robert; Fling, Rick; McClung, Christina; Robitaille, George

2005-01-01

...) unitizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 668 (NAEVA Geophysics, Inc.)

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing they PG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinate by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Open Field Scoring Record No. 299

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 638

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Robitaille, George; Boutin, Matthew; Archiable, Robert; McClung, Christina

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Woods Scoring Record Number 486

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Variedades de batatinha (Solanum tuberosum L.. I - Comportamento de 12 variedades procedentes da Holanda, Alemanha e Suécia Behavior of twelve potato varieties from European sources

Directory of Open Access Journals (Sweden)

O. J. Boock

1956-01-01

Full Text Available No presente trabalho são relatadas experiências com 12 variedades de batatinha (Solanum tuberosum L., recebidas da Holanda (Prinslander, Irene, Froma e Barima, Alemanha (Merkur, Sabina, Linda e Concordia e Suécia Konsuragis, Eigenheimer, Voran e Jätte-Bintje. Essas experiências, em número de seis, das quais três no chamado período "da sêca" (março-julho e três no "das águas" (setembro-janeiro, foram executadas nas localidades de Campinas, Louveira o Capão Bonito, no Estado de São Paulo. Ficou evidenciado o seguinte: a dado o bom estado de brotação dos tubérculos, as porcentagens de falhas no plantio "da sêca" foram baixas; já no plantio "das águas", as variedades de brotação lenta, como "Voran" e "Sabina", falharam muito; b "Prinslander" e "Konsuragis" resistiram bem à sêca prolongada, e "Barima" o "Linda" mostraram ser muito sensíveis; c "Linda", "Voran" e "Merkur", principalmente a primeira destas, apresentaram boa resistência a Phytophthora infestans, e "Jätte-Bintje" foi muito suscetível; "Voran", "Irene", "Prinslander" e "Barima" não ofereceram resistência a Alternaria solani; d "Merkur" e "Konsuragis" foram as mais produtivas para as duas épocas de plantio, sendo que "nas águas", "Eigenheimer", "Barima", "Concordia" e Jätte-Bintje", também produziram bem. Outros aspectos relacionados com variedades foram estudados.Twelve potato varieties imported from Holland (Prinslander, Irene, Froma, and Barima, Germany (Merkur, Sabina, Linda, and Concordia, and Sweden (Konsuragis, Eigenheimer, Voran, and Jätte-Bintje were compared in six experiments carried out at three different localities in the state of São Paulo (Campinas, Louveira, and Capão Bonito. The experiments were planted twice a year, once during the so-called dry season (March lo July, and another time during the rainy season (September to March. The following results were obtained: a plantings made in the dry season had a good stand, whereas this was

The effect of butterfly-scale inspired patterning on leading-edge vortex growth

Science.gov (United States)

Wilroy, Jacob Aaron

Leading edge vortices (LEVs) are important for generating thrust and lift in flapping flight, and the surface patterning (scales) on butterfly wings is hypothesized to play a role in the vortex formation of the LEV. To simplify this complex flow problem, an experiment was designed to focus on the alteration of 2-D vortex development with a variation in surface patterning. Specifically, the secondary vorticity generated by the LEV interacting at the patterned surface was studied, as well as the subsequent effect on the LEV's growth rate and peak circulation. For this experiment, rapid-prototyped grooves based on the scale geometry of the Monarch butterfly (Danaus plexippus) were created using additive manufacturing and were attached to a flat plate with a chordwise orientation, thus increasing plate surface area. The vortex generated by the grooved plate was then compared to a smooth plate case in an experiment where the plate translated vertically through a 2 x 3 x 5 cubic foot tow tank. The plate was impulsively started in quiescent water and flow fields at Rec = 1416, 2833, and 5667 are examined using Digital Particle Image Velocimetry (DPIV). The maximum vortex formation number is 2.8 and is based on the flat plate travel length and chord length. Flow fields from each case show the generation of a secondary vortex whose interaction with the shear layer and LEV caused different behaviors depending upon the surface type. The vortex development process varied for each Reynolds number and it was found that for the lowest Reynolds number case a significant difference does not exist between surface types, however, for the other two cases the grooves affected the secondary vortex's behavior and the LEV's ability to grow at a rate similar to the smooth plate case.

Section urétérale au cours d’un traumatisme pénétrant de l’abdomen: à propos d’un cas et revue de la littérature

Directory of Open Access Journals (Sweden)

A. Moataz

2017-12-01

Conclusions: Les lésions urétérales post-traumatiques non diagnostiquées à temps sont corrélées à une morbidité et une mortalité élevée. Un index de suspicion élevé permettrait un diagnostic rapide et une prise en charge à temps.

Scientific Presentations on High Temperature Superconductivity and Cryogenic Power Research from 2005-2013

Science.gov (United States)

2013-11-01

which uses higher fields of 3.6T, and the 7T magnets used for the Mach 10 speed test track based MagLev trains at Holloman Air Force Base (AFB...STEM AirCamp Outreach T. Haugan, E. Brewster, C. Ebbing Superconductivit y Basic Science and Technology, and MagLev Train Demonstration 12-Jul

"Matrix : Revolutsiooni" esilinastusele on ostetud üle 700 pileti

Index Scriptorium Estoniae

2003-01-01

Andy ja Larry Wachowski ulmefilmide triloogia 3. osa "Matrix : Revolutsioon" ("The Marix Revolutions") jõuab 5. novembril esilinastuseni korraga enam kui 50 riigis, sealhulgas MPDE vahendusel ka Eestis

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record No. 396

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Boutin, Matthew; Fling, Rick; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record No. 268

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Fling, Rick; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Blind Grid Scoring Record Number 431

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Blind Grid Scoring Record No. 397

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Robitaille, George; Boutin, Matthew; Fling, Rick; McClung, Christina

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site. Open Field Scoring Record Number 154

National Research Council Canada - National Science Library

Overbay, Larry

2004-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 379

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

... (UXO) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. Scoring Records have been coordinated by Larry Overbay and the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 354

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Archiable, Robert; McClung, Christina

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record No. 311

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Boutin, Matthew; Fling, Rick; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Recording Number 231 (Human Factors Applications, Inc.)

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbuy and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 129

National Research Council Canada - National Science Library

Overbay, Larry

2004-01-01

...) utilizing the APO Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 229

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Boutin, Matthew; Fling, Rick; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site, Open Field Scoring Record Number 411

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 169

National Research Council Canada - National Science Library

Overbay, Larry; Archiable, Robert; McClung, Christina; Robitaille, George

2005-01-01

...) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 201

National Research Council Canada - National Science Library

Overbay, Larry, Jr; Fling, Rick; Robitaille, George

2004-01-01

...) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 165

National Research Council Canada - National Science Library

Overbay, Larry

2004-01-01

...) utilizing the APO Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Kaugeks jäänud jant / Gert Kiiler

Index Scriptorium Estoniae

Kiiler, Gert

2007-01-01

DVDl ilmunud film "Borat - kultuurialased õppetunnid Ameerikast abiks suursuguse Kasahstani riigi ülesehitamisel" : režissöör Larry Charles, peaosas Sacha Baron Cohen : Ameerika Ühendriigid 2006

Standardized UXO Technology Demonstration Site, Blind Grid Scoring Record No. 671

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

... (UXO) utilizing the APG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Deomostration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 245

National Research Council Canada - National Science Library

Overbay, Larry

2005-01-01

... (UXO) utilizing the YPG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

Standardized UXO Technology Demonstration Site Open Field Scoring Record Number 675

National Research Council Canada - National Science Library

Overbay, Larry; Robitaille, George

2005-01-01

... (UXO) utilizing the APG Standardized UXO Technology Demonstration Site Open Field. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Scoring Committee...

77 FR 26008 - Ocean Transportation Intermediary License; Applicants

Science.gov (United States)

2012-05-02

.... Forth-Matthews, President, Application Type: New OFF License. Azimuth Lines Inc. (OFF), 111 Ivy Lane.... (NVO), 1000 Lakes Drive, 260, West Covina, CA 91760, Officers: Larry Lee, Treasurer (Qualifying...

77 FR 7628 - Self-Regulatory Organizations; New York Stock Exchange LLC; NYSE Amex LLC; Order Instituting...

Science.gov (United States)

2012-02-13

... October 17, 2011 (``Themis Letter''); Garret Cook, dated November 4, 2011 (``Cook Letter''); James.... Larry Paden, Bright Trading, dated December 1, 2011 (``Paden Letter''); Thomas Dercks, dated December 1...

75 FR 58435 - Membership of the Senior Executive Service Standing Performance Review Boards

Science.gov (United States)

2010-09-24

..., ROBERT N ASSOCIATE DEPUTY ATTORNEY GENERAL MONACO, LISA ASSOCIATE DEPUTY ATTORNEY GENERAL BURROWS... GENERAL MASON, KAROL V DEPUTY ASSOCIATE ATTORNEY GENERAL TRIBE, LARRY H SENIOR COUNSELOR FOR ACCESS TO...

Standardized UXO Technology Demonstration Site Blind Grid Scoring Record No. 213

National Research Council Canada - National Science Library

Overbay, Larry; Archiable, Robert; McClung, Christina; Robitaille, George

2005-01-01

... (UXO) utilizing the YPG Standardized UXO Technology Demonstration Site Blind Grid. The scoring record was coordinated by Larry Overbay and by the Standardized UXO Technology Demonstration Site Site Scoring Committee...

Consensus Through Conversation How to Achieve High-Commitment Decisions

CERN Document Server

Dressler, Larry

2006-01-01

Facilitation expert Larry Dressler's Consensus Through Conversation is a guide for the effective facilitation and practice of one of business's most popular - but most widely misunderstood - decision-making models: consensus.

Bogi i monstrõ, ili biografija Supermena / Olga Marsheva

Index Scriptorium Estoniae

Marsheva, Olga

2007-01-01

Ameerika tuntuimad koomiksikunstnikud Larry Hama, Stan Lee, Jerry Seagel, Bob Kain, Frank Miller ja nende loodud tegelaskujud. Ka briti kirjanik Alan Moore, kellele ei meeldi oma kangelastest tehtud ekraniseeringuid vaadata

78 FR 41032 - Proposed Information Collection; Comment Request; Foreign Availability Procedures

Science.gov (United States)

2013-07-09

... comments to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of Commerce, Room 6616... instrument and instructions should be directed to Larry Hall, BIS ICB Liaison, (202) 482-4895, Lawrence.Hall...

Lev D. Landau: his life and work

International Nuclear Information System (INIS)

Janouch, F.

1979-01-01

A biographical portrait of the Soviet theoretical physicist as presented at a CERN Colloquium in June 1978. A selected list of 39 scientific papers, and 18 references to his work in books and articles, are appended. (Auth.)

Üleväärsusest / Jan Kaus

Index Scriptorium Estoniae

Kaus, Jan, 1971-

2005-01-01

Vastukaja art.: Raid, Juku-Kalle. Alla mõistuse! // Postimees. - (2005/Sep/29) - Lk. 21. Artikli kaasautorid on Toomas Kümmel ja Sven Kivisildnik. Vt ka vastukaja: Rein Veidemann. Häda mõistuse pärast, Postimees, 3. okt., lk. 17

Lev Semjonovitsj Vygotskij og den kulturhistoriske psykologi

DEFF Research Database (Denmark)

Klitmøller, Jacob; Hviid, Pernille

2017-01-01

. Forfatterne legger vekt på å formidle de forskjellige retningenes forståelse av normale utviklingsforløp i vår tid, men ser det også i lys av en mer bekymringsskapende utvikling. Vi møter klassisk psykoanalyse, nyere psykoanalytiske perspektiver, tilknytningsteori, Daniel Sterns, Piagets og Vygotskijs...

Paradiis 2.0 / Laurie Werner

Index Scriptorium Estoniae

Werner, Laurie

2014-01-01

Oracle'i tegevjuht Larry Ellison ostis 98% Hawai saarest Lanaist. Ettevõtja soovib rajada sinna tööstuspiirkondada, võtta kasutusele päikeseenergiarajatisi, tuua saarele elektriautosid ja suurendada elanikkonda

78 FR 41032 - Proposed Information Collection; Comment Request; Special Comprehensive License

Science.gov (United States)

2013-07-09

... to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of Commerce, Room 6616, 14th... instrument and instructions should be directed to Larry Hall, BIS ICB Liaison, (202) 482-4895, Lawrence.Hall...

77 FR 24915 - Endangered and Threatened Wildlife and Plants; Revising the Proposed Special Rule for the Utah...

Science.gov (United States)

2012-04-26

.... FOR FURTHER INFORMATION CONTACT: Larry Crist, Field Supervisor, (telephone 801-975-3330; facsimile 801... emerge from their burrows by mid to late June at which time they are foraging independently (Hoogland...

Borat tungib psüühesse / Rain Tolk

Index Scriptorium Estoniae

Tolk, Rain, 1977-

2006-01-01

Briti koomik Sacha Baron Cohen ja tema loodud peategelasega film "Borat - kultuurialased õppetunnid Ameerikast abiks suursuguse Kasahstani riigi ülesehitamisel", režissöör Larry Charles : Ameerika Ühendriigid 2006

TSD acceptance testing in Australia

OpenAIRE

Wix, Richard

2014-01-01

Structural Session 3: Current Applications Moderated by Larry Scofield This presentation was held at the Pavement Evaluation 2014 Conference, which took place from September 15-18, 2014 in Blacksburg, Virginia. Presentation only

Kas Merrillis õnnestub korrata New Yorgi börsi edu? / Matthew Goldstein, Emily Thornton

Index Scriptorium Estoniae

Goldstein, Matthew

2007-01-01

Juhivahetusest ja tulevikuperspektiividest Merill Lynchi investeerimispangas. Vt. samas: Mara Der Hovanesian. Miks mitte Larry Fink?; Karen Young. Kuldsed langevarjud. Lisa: Kui nad täna lahkuksid (kümne tuntud tippjuhi lahkumispaketid)

77 FR 2270 - Proposed Information Collection; Comment Request; Firearms Convention

Science.gov (United States)

2012-01-17

... Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of Commerce, Room 6616, 14th and... and instructions should be directed to Larry Hall, BIS ICB Liaison, (202) 482-4895, Lawrence[email protected

Reduced-order aeroelastic model for limit-cycle oscillations in vortex-dominated unsteady airfoil flows

Science.gov (United States)

Suresh Babu, Arun Vishnu; Ramesh, Kiran; Gopalarathnam, Ashok

2017-11-01

In previous research, Ramesh et al. (JFM,2014) developed a low-order discrete vortex method for modeling unsteady airfoil flows with intermittent leading edge vortex (LEV) shedding using a leading edge suction parameter (LESP). LEV shedding is initiated using discrete vortices (DVs) whenever the Leading Edge Suction Parameter (LESP) exceeds a critical value. In subsequent research, the method was successfully employed by Ramesh et al. (JFS, 2015) to predict aeroelastic limit-cycle oscillations in airfoil flows dominated by intermittent LEV shedding. When applied to flows that require large number of time steps, the computational cost increases due to the increasing vortex count. In this research, we apply an amalgamation strategy to actively control the DV count, and thereby reduce simulation time. A pair each of LEVs and TEVs are amalgamated at every time step. The ideal pairs for amalgamation are identified based on the requirement that the flowfield in the vicinity of the airfoil is least affected (Spalart, 1988). Instead of placing the amalgamated vortex at the centroid, we place it at an optimal location to ensure that the leading-edge suction and the airfoil bound circulation are conserved. Results of the initial study are promising.

75 FR 54779 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2010-09-09

... Pancakes and Larry's East Colfax Avenue. Trading Post (now Mama's Caf[eacute], Herbs and Art, and Purple... conclusively shown to increase the risk of lung cancer. Dispersion quickly dilutes radon emanating from radium...

Kolmas "Matrix" põrutab kuulipildujaga / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2003-01-01

Andy ja Larry Wachowski ulmefilmide triloogia 3. osa "Matrix : Revolutsioon" ("The Marix Revolutions") jõuab 5. novembril kell 16 meie aja järgi esilinastuseni korraga paljudes riikides, sealhulgas MPDE vahendusel ka Eestis

76 FR 80445 - Self-Regulatory Organizations; New York Stock Exchange LLC; NYSE Amex LLC; Notice of Designation...

Science.gov (United States)

2011-12-23

..., dated October 17, 2011; Garret Cook, dated November 4, 2011; James Johannes, dated November 27, 2011... November 30, 2011; Dr. Larry Paden, Bright Trading, dated December 1, 2011; Thomas Dercks, dated December 1...

Roughness Effects on the Formation of a Leading Edge Vortex

Science.gov (United States)

Elliott, Cassidy; Lang, Amy; Wahidi, Redha; Wilroy, Jacob

2017-11-01

Microscopic scales cover the wings of Monarch butterflies, creating a patterned surface that acts as a natural energy capture mechanism. This patterning is thought to delay the growth of the leading edge vortex (LEV) produced by the flapping motion of a wing. Increased skin friction caused by the scales leads to a weaker LEV being shed into the butterfly's wake, lessening drag and increasing flight efficiency. To test how this roughness effects LEV formation, a plate of random roughness was designed in SolidWorks and printed on the Objet 30 Pro 3D printer. A 2x3x5 cubic foot tow tank was used to test the rough plate at Reynold's numbers of 1500, 3000, and 6000 (velocities of 8, 16, and 32 mm/s) at an angle of attack of 45 degrees. Images were captured of the LEV generated when the plate was towed upwards through the particle-seeded flow. These images were used to determine the XY velocity of the particles using a technique called Digital Particle Image Velocimetry (DPIV). Codes written in MATLAB were used to track and measure the strength of the LEV. Circulation values for the randomly-rough plate were then compared to the same values generated in a previous experiment that used a smooth plate and a grooved plate to determine the effect of the patterning on vortex development. Funding for this research project was provided by the National Science Foundation under the Research Experience for Undergraduates (REU) program (REU Supplement CBET 1628600 under CBET 1335848).

Impact de la variabilité climatique sur le régime des cours d'eau du ...

African Journals Online (AJOL)

... pluies de la “saison sèche” d'été (juillet et août) sont plus élevées depuis quelques décennies, ce qui entretient vraisemblablement une humidité du sol plus élevée favorable au ruissellement au début de la crue d'automne. Mots clefs : changement climatique ; climat équatorial ; séries chronologiques ; Sud Cameroun.

Using magnetic levitation for non-destructive quality control of plastic parts.

Science.gov (United States)

Hennek, Jonathan W; Nemiroski, Alex; Subramaniam, Anand Bala; Bwambok, David K; Yang, Dian; Harburg, Daniel V; Tricard, Simon; Ellerbee, Audrey K; Whitesides, George M

2015-03-04

Magnetic levitation (MagLev) enables rapid and non-destructive quality control of plastic parts. The feasibility of MagLev as a method to: i) rapidly assess injection-molded plastic parts for defects during process optimization, ii) monitor the degradation of plastics after exposure to harsh environmental conditions, and iii) detect counterfeit polymers by density is demonstrated. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Impact de la restructuration de la taxe d'accise sur le tabac aux ...

International Development Research Centre (IDRC) Digital Library (Canada)

Aux Philippines, le taux de tabagisme est élevé et les taxes sur les produits du tabac, peu élevées. La meilleure façon de redresser la situation consiste à adopter des lois qui aug- mentent considérablement les taxes. Une loi restructurant les taxes sur les produits du tabac, qui comporte une forte hausse de la taxe d'accise ...

76 FR 19998 - Supplemental Funding Under the Food and Drug Administration Pediatric Device Consortia Grant Program

Science.gov (United States)

2011-04-11

...: Linda C. Ulrich, Office of Orphan Products Development, Food and Drug Administration, 10903 New... projects through the development process, including product identification, prototype design, device...

Haute prévalence du Burnout dans les unités Tunisiennes prenant en charge des patients en fin de vie

Science.gov (United States)

Amamou, Badii; Bannour, Ahmed Souhaiel; Ben Hadj Yahia, Meriem; Ben Nasr, Selma; Ben Hadj Ali, Bechir

2014-01-01

Introduction Chez le personnel soignant, le burnout touche un infirmier sur trois. Ce taux est plus élevé dans les unités prenant en charge des patients en fin de vie. L'objectif de notre travail était d'évaluer la fréquence du burnout chez les infirmiers qui travaillent en soins de fin de vie. Méthodes Il s'agit d'une étude descriptive transversale réalisée entre le 1er Avril et le 31 Mai 2010. 60 infirmiers de six services de Sousse et de Monastir (Tunisie) ont été recrutés. L'évaluation du burnout a été réalisée par deux échelles: MBI (Maslach Burnout Inventory) et BMS (Burnout Measure Short version). Résultats La prévalence du burnout était de 70%; il était élevé chez 81.7%. 80% avaient un niveau élevé d'épuisement émotionnel, 70% avaient un niveau élevé de dépersonnalisation et 17% avaient un niveau bas de sentiment d'accomplissement personnel. Le burnout était plus élevé chez les hommes (70,8% vs 69,4%; p=0,013); ceux qui voulaient améliorer les conditions du travail (70.2% vs. 66.7%; p= 0.017); du salaire (70.2% vs. 66.7%; p= 0.017) et chez les infirmiers suivi en psychiatrie (71.4% vs. 69.8%; p= 0.008). Conclusion Dans notre étude le niveau de burnout était élevé chez les infirmiers prenant en charge des patients en fin de vie. Il était associé au sexe masculin et à l'insatisfaction des conditions de travail et du salaire. D'autres études longitudinales sont nécessaires pour suivre l'évolution de ce syndrome et mettre des stratégies de prévention adéquates. PMID:25584122

Matrix - kultusfilm, mis muutus müüdiks / Rando Tooming

Index Scriptorium Estoniae

Tooming, Rando

2003-01-01

Andy ja Larry Wachowski ulmefilmide triloogia 3. osa "Matrix : Revolutsioon" ("The Marix Revolutions") jõuab 5. novembril esilinastuseni korraga enam kui 50 riigis, sealhulgas MPDE vahendusel ka Eestis. Eesti filmikriitikute arvamusi Matrix'i fenomenist

Spacelab Life Sciences Research Panel

Science.gov (United States)

Sulzman, Frank; Young, Laurence R.; Seddon, Rhea; Ross, Muriel; Baldwin, Kenneth; Frey, Mary Anne; Hughes, Rod

2000-01-01

This document describes some of the life sciences research that was conducted on Spacelab missions. Dr. Larry Young, Director of the National Space Biomedical Research Institute, provides an overview of the Life Sciences Spacelabs.

Transport Mechanisms Governing initial Leading-Edge Vortex Development on a Pitching Wing

Science.gov (United States)

Wabick, Kevin; Berdon, Randall; Buchholz, James; Johnson, Kyle; Thurow, Brian

2017-11-01

The formation and evolution of Leading Edge Vortices (LEVs) are ubiquitous in natural fliers and maneuvering wings, and have a profound impact on aerodynamic loads. The formation of an LEV is experimentally investigated on a pitching flat-plate wing of aspect-ratio 2, and dimensionless pitch rates of k = Ωc / 2 U of 0.1, 0.2, and 0.5, at a Reynolds number of 104. The sources and sinks of vorticity that contribute to the growth and evolution of the LEV are investigated at spanwise regions of interest, and their relative balance is compared to other wing kinematics, and the case of a two-dimensional pitching wing. This work is supported by the Air Force Office of Scientific Research (Grant Number FA9550-16-1-0107, Dr. Douglas Smith, program manager).

Sénégal

African Journals Online (AJOL)

SARAH

30 nov. 2017 ... RÉSUMÉ. Objectif : Cette étude vise à connaître le régime alimentaire des poissons élevés dans les étangs piscicoles en. Basse-Casamance. Méthodes et résultats : Afin de fournir des informations sur la nourriture des poissons élevés, des prélèvements d'eau des étangs et de contenus stomacaux des ...

Levetiracetam-induced interstitial nephritis in a patient with glioma.

Science.gov (United States)

Mahta, Ali; Kim, Ryan Y; Kesari, Santosh

2012-01-01

A 45-year-old man with a new diagnosis of low grade glioma was started on an escalating dose of levetiracetam (Lev) for seizure management. He gradually developed intractable nausea/vomiting and a high creatinine concentration due to acute renal failure which was attributed to Lev-induced interstitial nephritis. The medication was changed and his renal function rapidly improved to his baseline. Copyright © 2011 Elsevier Ltd. All rights reserved.

Wa Wa We Wa! / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2006-01-01

Briti koomik Sacha Baron Cohen ja tema loodud peategelasega film "Borat - kultuurialased õppetunnid Ameerikast abiks suursuguse Kasahstani riigi ülesehitamisel", režissöör Larry Charles : Ameerika Ühendriigid 2006. Lisaks "Seigad Coheni elust"

75 FR 44050 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2010-07-27

..., Mitchell L. Carmen, Christopher R. Cone, Walter O. Connelly, Stephen B. Copeland, Armando P. D'Angeli..., Andrew C. Kelly, Jason W. King, James T. Leek, Billy J. Lewis, Velmer L. McClelland, Larry McCoy, Sr...

78 FR 26107 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

Science.gov (United States)

2013-05-03

... Christopher W. Bailey (OH), Kent S. Bills (IN), Bobby B. Brown (VA), Maryland A. Chandler (KY), Ronald D. Clark (AR), Larry L. Eberly (PA), Steven J. Fessler (IL), Michael R. Fisher (IA), Mark A. Krause (PA...

Nii loodi fond Mälestus / Linda Järve

Index Scriptorium Estoniae

Järve, Linda, 1946-

2003-01-01

12. dets. 2002.a. kirjutasid sihtasutuse Eesti Rahvuskultuuri Fond nõukogu esimees Eri Klas ja Tallinna noorte klubi Kodulinn juhataja Tiina Mägi alla lepingule, millega pandi alus Eesti Rahvuskultuuri Fondi uuele nimelisele allfondile Mälestus

La casa linda de los habitantes del mar

OpenAIRE

Depestre, Leonardo

2009-01-01

Se describe el funcionamiento del Acuario Nacional de Cuba, enfatizando en la atención a los mamíferos marinos que se exhiben (focas y leones marinos), así como también aquellos que forman parte de las actividades didáctico recreativas como son los delfines y los lobos marinos.

Nägemispuudega lugejad said kokku Tartus / Linda Jahilo

Index Scriptorium Estoniae

Jahilo, Linda, 1955-

2007-01-01

Ülevaade 24. oktoobril Tartu Linnaraamatukogus toimunud ettelugemispäeva märkivast lugejate konverentsist. Ürituse korraldajateks olid Eesti Pimedate Raamatukogu ja Lõuna-Eesti Pimedate Ühing koostöös Tartu linnaraamatukoguga

Hester Prynne and Linda Lovelace: Pure or Prurient.

Science.gov (United States)

Berger, Gertrude

A June 21, 1973, Supreme Court ruling yielded jurisdiction in matters of obscenity to individual communities and the decision as to what is prurient to"contemporary community standards." This ruling leaves the courts in the powerful position of surgeon, judge, film critic, and arbiter of community taste. An analysis of past court cases…

The new era of cyber marketing / interv. Alina Lisina

Index Scriptorium Estoniae

2005-01-01

Vestlusringis internetireklaamist osalesid Juris Mendzinsh, Linda Saulite, Ilze Taurina, Daina Misina, Edgars Rozentals, Gatis Veikshins, Reinis Zitmanis, Agris Strautnieks, Jurijs Zarinsh, Ivars Bauls, Martinsh Labans ja Vents Dorinsh

Will Instructors Save Time Using a Specifications Grading System?

Directory of Open Access Journals (Sweden)

Sarah Grace Prescott

2015-08-01

Full Text Available Review of: Specifications Grading: Restoring Rigor, Motivating Students, and Saving Faculty Time; Linda Nilson and Claudia J. Stranny; (2014. Stylus Publishing, Sterling, VA. 184 pages.

Clinical features of benign epilepsy of childhood with centrotemporal spikes in chinese children

Science.gov (United States)

Liu, Meng-Jia; Su, Xiao-jun; MD, Xiu-Yu Shi; Wu, Ge-fei; Zhang, Yu-qin; Gao, Li; Wang, Wei; Liao, Jian-xiang; Wang, Hua; Mai, Jian-ning; Gao, Jing-yun; Shu, Xiao-mei; Huang, Shao-ping; Zhang, Li; Zou, Li-Ping

2017-01-01

Abstract This multicenter clinical trial was conducted to examine current practice of benign epilepsy with centrotemporal spikes and especially address the question that in what circumstances 1 antiepileptic drug (AED) should be preferred. Twenty-five medical centers participate in this clinical trial. The general information, clinical information, and treatment status were collected under the guidance of clinicians and then analyzed. Difference between different treatment groups was compared, and usefulness of the most commonly used AEDs was evaluated. A total of 1817 subjects were collected. The average age of the subject was 8.81 years. The average age of onset is 6.85 years (1–14 years). Male-to-female ratio is 1.13:1. A total of 62.9% of the patients are receiving monotherapies, and 10.6% are receiving multidrug therapy. Both age and course of disease of treated rolandic epilepsy (RE) patients are significantly different from those of untreated patients. Bilateral findings on electroencephalography (EEG) are less seen in patients with monotherapy compared with patients with multidrug therapy. Except for 25.4% patients not taking any AEDs, oxcarbazepine (OXC), sodium valproate (VPA), and levetiracetam (LEV) are the most commonly used 3 AEDs. VPA and LEV are commonly used in add-on therapy. OXC and LEV are more effective as monotherapy than VPA. Age of onset of Chinese RE patients is 6.85 years. Bilateral findings on EEG could be a risk factor to require multidrug therapy. In Chinese patients, OXC, VPA, and LEV are most commonly used AEDs as monotherapy and OXC and LEV are more effective than VPA. PMID:28121917

Social and environmental changes: universal peace possible solely through creating of job opportunities in environment industries

International Nuclear Information System (INIS)

Dip Ing Mohamad Sani

2006-01-01

Until recent there was a speed gap in the traffic branches between the track bound wheel-on-rail systems and aircraft. But this gap is now closing by the super high speed MagLev train on the base of track bound Magnetic Levitation technology. This one may now become one of the key technologies for the 21st century, as it combines essential environmental and economic advantage: i] Its propulsion energy is electricity - which means that Renewable Energies may be applied without reservation, 2] Its ecological advance vice versa aircraft is huge - pollution of the higher atmosphere e.g. differs by a factor 40 per person x kilometer, 3] At a speed of more than 200 km per hour, energy consumption is lower than and maintenance costs range at ca. 3 of which have to be calculated for high speed wheel-on-rail systems, 4] Short distance flights which stress as well the budgets of the airlines as exceptionally the environment, become obsolete where MagLev relations exist. A MagLev connection can be regarded as the quickest relation for passengers at distances of less than ca. 1000 km, 5] Intermodal traffic network as well as airport connections, which enlarge their focus according to the radio telescope system well-known from astronomy, are supported by the super high speed MagLev with a velocity up to 550 km per hour, 6] Zones of excellence and high performance management may be created at MagLev terminals - with global market access provided. By these factors, social development and environmental advance may be well-combined on the base of Renewable Energy use in a modern traffic, distribution and logistic system network

Direct numerical simulation of supercritical gas flow in complex nanoporous media: Elucidating the relationship between permeability and pore space geometry

Science.gov (United States)

Landry, C. J.; Prodanovic, M.; Eichhubl, P.

2015-12-01

Mudrocks and shales are currently a significant source of natural gas and understanding the basic transport properties of these formations is critical to predicting long-term production, however, the nanoporous nature of mudrocks presents a unique challenge. Mudrock pores are predominantly in the range of 1-100 nm, and within this size range the flow of gas at reservoir conditions will fall within the slip-flow and early transition-flow regime (0.001 clays). Here we present a local effective viscosity lattice Boltzmann model (LEV-LBM) constructed for flow simulation in the slip- and early-transition flow regimes, adapted here for complex geometries. At the macroscopic scale the LEV-LBM is parameterized with local effective viscosities at each node to capture the variance of the mean free path of gas molecules in a bounded system. The LEV-LBM is first validated in simple tube geometries, where excellent agreement with linearized Boltzmann solutions is found for Knudsen numbers up to 1.0. The LEV-LBM is then employed to quantify the length effect on the apparent permeability of tubes, which suggests pore network modeling of flow in the slip and early-transition regime will result in overestimation unless the length effect is considered. Furthermore, the LEV-LBM is used to evaluate the predictive value of commonly measured pore geometry characteristics such as porosity, pore size distribution, and specific solid surface area for the calculation of permeability. We show that bundle of tubes models grossly overestimate apparent permeability, as well as underestimate the increase in apparent permeability with decreasing pressure as a result of excluding topology and pore shape from calculations.

"Matrix" sobitub iga filosoofiaga / Rando Tooming

Index Scriptorium Estoniae

Tooming, Rando

2003-01-01

Andy ja Larry Wachowski ulmefilmide triloogia "Matrix" fenomeni analüüsist ajakirja "Vikerkaar" 2003. aasta 9. numbris, kus sellele on pühendatud nelja filosoofi artiklid ( Slavoj Zhizhek, Jüri Eintalu, Bruno Mölder, Tanel Tammet)

Effects of Oxcarbazepine and Levetiracetam on Calcium, Ionized Calcium, and 25-OH Vitamin-D3 Levels in Patients with Epilepsy.

Science.gov (United States)

Aksoy, Duygu; Güveli, Betül Tekin; Ak, Pelin Doğan; Sarı, Hüseyin; Ataklı, Dilek; Arpacı, Baki

2016-02-29

The primary objective of the present study was to further elucidate the effects of oxcarbazepine (OXC) and levetiracetam (LEV) monotherapies on the bone health status of patients with epilepsy. This study included 48 patients who attended our epilepsy outpatient clinic, had a diagnosis of epilepsy, and were undergoing either OXC or LEV monotherapy and 42 healthy control subjects. The demographic and clinical features of the patients, including gender, age, onset of disease, daily drug dosage, and duration of disease, were noted. Additionally, the calcium, ionized calcium, and 25-OH vitamin-D3 levels of the participants were prospectively evaluated. The 25-OH vitamin-D3, calcium, and ionized calcium levels of the patients taking OXC were significantly lower than those of the control group. These levels did not significantly differ between the patients taking LEV and the control group, but there was a significant negative relationship between daily drug dose and ionized calcium levels in the LEV patients. In the present study, anti-epileptic drugs altered the calcium, ionized calcium, and 25-OH vitamin-D3 levels of epilepsy patients and resulted in bone loss, abnormal mineralization, and fractures. These findings suggest that the calcium, ionized calcium, and 25-OH vitamin-D3 levels of patients with epilepsy should be regularly assessed.

Vaidlused või monoloogid? / Redi Koobak, Raili Põldsaar

Index Scriptorium Estoniae

Koobak, Redi

2006-01-01

Arvustus: Feministlikud vaidlused : filosoofiline mõttevahetus / [Seyla Benhabib, Judith Butler, Nancy Freiser, Drucilla Cornell] ; inglise keelest tõlkinud Merilin Sikk ; [koostaja Linda Nicholson]. Tallinn : Tallinna Ülikooli Kirjastus, 2006

Effets du calcium alimentaire sur les paramètres de reproduction de ...

African Journals Online (AJOL)

Le taux optimal de calcium induisant une meilleure reproduction varie de 12,02 % à 16,01 %. En outre, les animaux qui ont été nourris à ces régimes ont eu une relative longévité, un nombre élevé de pontes, une durée d'incubation réduite et un taux élevé d'éclosion des oeufs, contrairement aux régimes à base de ...

Research

African Journals Online (AJOL)

abp

5 mai 2014 ... (63/106) se sont avérés être positifs pour les microorganismes pathogènes. Soixante huit (78) germes ... pays en voie de développement à un risque élevé de mortalité. Un diagnostic microbiologique efficace ... effet, le caractère poly microbien élevé des liquides péritonéaux a été démontré dans plusieurs ...

Nazvan samõi vlijatelnõi tshelovek v iskusstve

Index Scriptorium Estoniae

2008-01-01

Ajakirja ArtReview ekspertide poolt 2008. aastal valitud 100 kunstimaailmas mõjukaima inimese nimekirja "The Power 100" juhib inglise skulptor Damien Hirst. Teisel kohal on ameerika galerist Larry Gagosian ja kolmandal kohal kunstimuuseumi MoMA direktor Kathy Halbreich

Clinical trial design and rationale of the Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3 (MOMENTUM 3) investigational device exemption clinical study protocol.

Science.gov (United States)

Heatley, Gerald; Sood, Poornima; Goldstein, Daniel; Uriel, Nir; Cleveland, Joseph; Middlebrook, Don; Mehra, Mandeep R

2016-04-01

The HeartMate 3 left ventricular assist system (LVAS; St. Jude Medical, Inc., formerly Thoratec Corporation, Pleasanton, CA) was recently introduced into clinical trials for durable circulatory support in patients with medically refractory advanced-stage heart failure. This centrifugal, fully magnetically levitated, continuous-flow pump is engineered with the intent to enhance hemocompatibility and reduce shear stress on blood elements, while also possessing intrinsic pulsatility. Although bridge-to-transplant (BTT) and destination therapy (DT) are established dichotomous indications for durable left ventricular assist device (LVAD) support, clinical practice has challenged the appropriateness of these designations. The introduction of novel LVAD technology allows for the development of clinical trial designs to keep pace with current practices. The prospective, randomized Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3 (MOMENTUM 3) clinical trial aims to evaluate the safety and effectiveness of the HeartMate 3 LVAS by demonstrating non-inferiority to the HeartMate II LVAS (also St. Jude Medical, Inc.). The innovative trial design includes patients enrolled under a single inclusion and exclusion criteria , regardless of the intended use of the device, with outcomes ascertained in the short term (ST, at 6 months) and long term (LT, at 2 years). This adaptive trial design includes a pre-specified safety phase (n = 30) analysis. The ST cohort includes the first 294 patients and the LT cohort includes the first 366 patients for evaluation of the composite primary end-point of survival to transplant, recovery or LVAD support free of debilitating stroke (modified Rankin score >3), or re-operation to replace the pump. As part of the adaptive design, an analysis by an independent statistician will determine whether sample size adjustment is required at pre-specified times during the study. A further 662

iiESI Wraps Up First International Conference | News | NREL

Science.gov (United States)

stochastic dynamical systems, seated alongside Linda Steg, a professor of psychology, to address the role of the integrated energy community by providing resources, events, and a channel of communication between

Applications of the Strategic Defense Initiative's Compact Accelerators

National Research Council Canada - National Science Library

Montanarelli, Nick

1992-01-01

...) was recently incorporated into the design of a cancer therapy unit at the Loma Linda University Medical Center, an SDI sponsored compact induction linear accelerator may replace Cobalt 60 radiation...

Katherine Brooke'ist / Tiina Lepiste

Index Scriptorium Estoniae

Lepiste, Tiina

2007-01-01

Ameerika teleseriaali "Vaprad ja ilusad" ("The Bold and the Beautiful") osatäitja Katherine Kelly Lang (Brooke). Artikli aluseks on Soap Opera Weekly ajakirjaniku Linda Susmani vestlus näitlejannaga

Tallinnas räägiti karjääriplaneerimise oskuste vajalikkusest / Margit Rammo

Index Scriptorium Estoniae

Rammo, Margit

2015-01-01

Karjäärioskuste teemalisel konverentsil Tallinnas osalesid karjäärispetsialistid Eestist, Lätist, Põhjamaadest, Iirimaalt. Vestlusest konverentsil osalenud Raimo Vuorineni, Bo Klindt Poulseni, Linda Darbey ja Kristina Orioniga

Lahesõjas viik / Ain Hinsberg

Index Scriptorium Estoniae

Hinsberg, Ain

2001-01-01

Helsingi ja Tallinna vahel liikuvate laevafirmade konkurents: Silja Line, Nordic Jet Line, Tallink ja Linda Line. Tabelid: reisijad laevaliinil Helsingi-Tallinn 1998-2001; Helsingi-Tallinna liinil kiirlaevade turuosad 1999-2000

10. VI avati Tartus Sadamateatris...

Index Scriptorium Estoniae

2005-01-01

Näitus "The 2D Cowboys and a Man from No Man's Land". New Mexico kunstnikud Larry Bob Phillips, Mathew Williams (Mad Dog), Doug Morris (grupeering 2D Cowboys) ja Eesti juurtega Pat Kikut eksponeerivad maali, joonistusi ja kollaazhe

Sacha baron Cohen - julge mees / Timo Diener

Index Scriptorium Estoniae

Diener, Timo

2006-01-01

Eesti kinodesse on jõudnud briti koomiku Sacha Baron Coheni loodud peategelasega USA film "Borat - kultuurialased õppetunnid Ameerikast abiks suursuguse Kasahstani riigi ülesehitamisel" : režissöör Larry Charles. Filmi peaosalisest ja filmi seiklusrikkast võtteperioodist

Teratogenic study of phenobarbital and levamisole on mouse fetus liver tissue using biospectroscopy.

Science.gov (United States)

Ashtarinezhad, Azadeh; Panahyab, Ataollah; Shaterzadeh-Oskouei, Shahrzad; Khoshniat, Hessam; Mohamadzadehasl, Baharak; Shirazi, Farshad H

2016-09-05

Biospectroscopic investigations have attracted attention of both the clinicians and basic sciences researchers in recent years. Scientists are discovering new areas for FTIR biospectroscopy applications in medicine. The aim of this study was to measure the possibility of FTIR-MSP application for the recognition and detection of fetus abnormalities after exposure of pregnant mouse to phenobarbital (PB) and levamisole (LEV) alone or in combination. PB is one of the most widely used antiepileptic drugs (AEDs), with sedative and hypnotic effects. When used by pregnant women, it is known to be a teratogenic agent. LEV is an antihelminthic drug with some applications in immune-deficiency as well as colon cancer therapy. Four groups of ten pregnant mice were selected for the experiments as follows: one control group received only standard diet, one group was injected with 120mg/kg of BP, one group was injected with 10mg/kg of LEV, and the last group was treated simultaneously with both BP and LEV at the above mentioned doses. Drugs administration was performed on gestation day 9 and fetuses were dissected on pregnancy day 15. Each dissected fetus was fixed, dehydrated and embedded in paraffin. Sections of liver (10μm) were prepared from control and treated groups by microtome and deparaffinized with xylene. The spectra were taken by FTIR-MSP in the region of 4000-400cm(-1). All the spectra were normalized based on amide II band (1545cm(-1)) after baseline correction of the entire spectrum, followed by classification using PCA, ANN and SVM. Both morphological and spectral changes were shown in the treated fetuses as compared to the fetuses in the control group. While cleft palate and C-R elongation were seen in PB injected fetuses, developmental retardation was mostly seen in the LEV injected group. Biospectroscopy revealed that both drugs mainly affected the cellular lipids and proteins, with LEV causing more changes in amide I and lipid regions than PB. Application of

Libavaida sugrusida uherles ja vurles kehus* / Maria Ulfsak-Šeripova

Index Scriptorium Estoniae

Ulfsak-Šeripova, Maria, 1981-

2010-01-01

Tim Burtoni filmist "Alice Imedemaal" (USA 2010), stsenarist Linda Woolverton, peaosades Mia Wasikowska, Johnny Depp. Lisaks kaks arvamust "3D poolt", autor Mann Jõgeda ja "3D vastu", autor Margit Tõnson

Paide linna ja gümnaasiumi spordihall = Paide city and upper secondary school sports building

Index Scriptorium Estoniae

2010-01-01

Paides Aedvilja 1 asuva spordihalli sisekujundusest. Sisearhitektid Ville Lausmäe ja Kadi Karmann (VL Sisearhitektuur). Akustik Linda Madalik. Hoone arhitektid: Karli Luik, Ralf Lõoke, Maarja Kask, Jaan Port (Salto AB)

Vajame arengut toetavat kooli / Raivo Juurak

Index Scriptorium Estoniae

Juurak, Raivo, 1949-

2012-01-01

Suurbritannia haridusprogrammist, kus õpilase arengut koolis maksimaalselt toetakse. Canterbury ülikooli haridusteaduskonna programmi „Kvaliteet õppe toetamisel” ehk QiSS (Quality in Study Support) direktori Linda Leith'i intervjuu põhjal

[Crusading and Chronicle Writing on the Medieval Baltic Frontier: A Companion to the Chronicle of Henry of Livonia] / Michael Amundsen

Index Scriptorium Estoniae

Amundsen, Michael

2012-01-01

Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham : Ashgate, 2011

Members of the Parliamentary Select Committee on Trade and Industry of the United Kingdom visit the CMS assembly hall.

CERN Multimedia

Patrice Loïez

2002-01-01

Left to right: Austin Ball, Martin O'Neill (Chairman), Richard Burden, Jonathan Djanogly, Lindsay Hoyle, Roger Berry, Linda Perham, Sir Robert Smith, Jackie Lawrence, Michel Della Negra, Tejinder Virdee, Ashok Kumar.

DVD-d. "Borat", "United 93", "Must Daalia", "Vimm 2" / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2007-01-01

Uued mängufilmide DVD-d : Larry Charlesi "Borat" (peaosas Sacha Baron Cohen; USA 2006), Paul Greengrassi "United 93" (USA 2006), Brian De Palma "Must Daalia" ("The Black Dahlia", USA 2006), Takashi Shimizu "Vimm 2" ("The Grudge 2", USA 2006)

Natalie Portman plaanib veritasu / Timo Diener

Index Scriptorium Estoniae

Diener, Timo

2006-01-01

Natalie Portman ulmepõnevikus "V nagu veritasu" ("V for Vendetta") : režissöör James McTeigue : USA - Saksamaa 2005. Aluseks on Alan Moore'i samanimeline koomiks, mille vennad Larry ja Andy Wachowski stsenaariumiks töötlesid

Kaks meest abielluvad / Timo Diener

Index Scriptorium Estoniae

Diener, Timo

2007-01-01

Komöödiafilm "Kui Chuck abiellub Larryga" ("I Now Pronounce You Chuck and Larry") : režissöör Dennis Dugan : osades Adam Sandler, Kevin James, Jessica Biel : Ameerika Ühendriigid 2007. Lisatud nimekiri "Adam Sandleri menukamad filmid"

A Lean Approach to Scheduling Systems Engineering Resources

Science.gov (United States)

2013-05-01

Boeing), Suzette Johnson (Northrop Grumman), Larry Mac- cherone (Rally Development), Don Reinertsen (Reinertsen & Associates), David Rico (Boe- ing...Change for Your Technology Business. Sequim, WA: Blue Hole Press 9. Burrows , Mike. (2010). Kanban in a Nutshell. Blog post. <http

Military Interventions in Sierra Leone: Lessons from a Failed State

National Research Council Canada - National Science Library

Woods, Larry J; Reese, Timothy R

2008-01-01

This study by Larry J. Woods and Colonel Timothy R. Reese analyzes the massive turmoil afflicting the nation of Sierra Leone, 1993-2002, and the efforts by a variety of outside forces to bring lasting stability to that small country...

Superconducting levitation applications to bearings and magnetic transportation

CERN Document Server

Moon, Francis C

1994-01-01

Presents the fundamental principles governing levitation of material bodies by magnetic fields without too much formal theory. Defines the technology of magnetic bearings, especially those based on superconductivity, and demonstrates the key roles that magnetics, mechanics and dynamics play in the complete understanding of magnetic levitation and its bearings. Features extensive figures and photos of Mag-Lev devices and summarizes recent U.S. research studies in an effort to regain the lead in Mag-Lev technologies

1239-IJBCS-Article-Samba Ndiaye

African Journals Online (AJOL)

KODJIO NORBERT

de Cordyla pinnata, une légumineuse arborée qui forme un parc agroforestier au Sénégal. Les analyses de sols ont montré des valeurs plus élevées pour N total, Ca échangeable et CEC sous le couvert de l'espèce. Pour le mil, la hauteur, les biomasses aérienne et racinaire ont également été plus élevées sur les sols SC.

Magnetic levitation and MHD propulsion

International Nuclear Information System (INIS)

Tixador, P.

1994-01-01

Magnetic levitation and MHD propulsion are now attracting attention in several countries. Different superconducting MagLev and MHD systems will be described concentrating on, above all, the electromagnetic aspect. Some programmes occurring throughout the world will be described. Magnetic levitated trains could be the new high speed transportation system for the 21st century. Intensive studies involving MagLev trains using superconductivity have been carried our in Japan since 1970. The construction of a 43 km long track is to be the next step. In 1991 a six year programme was launched in the United States to evaluate the performances of MagLev systems for transportation. The MHD (MagnetoHydroDynamic) offers some interesting advantages (efficiency, stealth characteristics, ..) for naval propulsion and increasing attention is being paid towards it nowadays. Japan is also up at the top with the tests of Yamato I, a 260 ton MHD propulsed ship. (orig.)

Magnetic levitation and MHD propulsion

Energy Technology Data Exchange (ETDEWEB)

Tixador, P [CNRS/CRTBT-LEG, 38 - Grenoble (France)

1994-04-01

Magnetic levitation and MHD propulsion are now attracting attention in several countries. Different superconducting MagLev and MHD systems will be described concentrating on, above all, the electromagnetic aspect. Some programmes occurring throughout the world will be described. Magnetic levitated trains could be the new high speed transportation system for the 21st century. Intensive studies involving MagLev trains using superconductivity have been carried our in Japan since 1970. The construction of a 43 km long track is to be the next step. In 1991 a six year programme was launched in the United States to evaluate the performances of MagLev systems for transportation. The MHD (MagnetoHydroDynamic) offers some interesting advantages (efficiency, stealth characteristics, ..) for naval propulsion and increasing attention is being paid towards it nowadays. Japan is also up at the top with the tests of Yamato I, a 260 ton MHD propulsed ship. (orig.).

The effect of levetiracetam on focal nocturnal epileptiform activity during sleep--a placebo-controlled double-blind cross-over study.

Science.gov (United States)

Larsson, Pål Gunnar; Bakke, Kristin A; Bjørnæs, Helge; Heminghyt, Einar; Rytter, Elisif; Brager-Larsen, Line; Eriksson, Ann-Sofie

2012-05-01

Electric Status Epilepticus during Sleep (ESES) occurs in children with and without epilepsy. It may be related to disturbances as autism spectrum disorder, attention-deficit hyperactivity disorder and acquired aphasia (Landau-Kleffner syndrome). Antiepileptic drug (AED) treatment has been reported in small studies without placebo control. This study was designed to assess AED effect in a placebo-controlled double-blind cross-over study. Levetiracetam (LEV) was chosen based on clinical evidence. Eighteen patients fulfilled the inclusion criteria. The mean spike index at baseline was 56, falling to a mean of 37 at the end of the LEV treatment period. Assessed with a 2-way ANOVA, there is a significant treatment effect (pdouble-blind cross-over study for any AED in patients with ESES. The effect of LEV is comparable with its effect in treatment of epileptic seizures. Copyright © 2012 Elsevier Inc. All rights reserved.

Dose-Response Head-to-Head Comparison of Inodilators Dobutamine, Milrinone, and Levosimendan in Chronic Experimental Pulmonary Hypertension.

Science.gov (United States)

Tavares-Silva, Marta; Alaa, Mohamed; Leite, Sara; Oliveira-Pinto, José; Lopes, Lucas; Leite-Moreira, Adelino F; Lourenço, André P

2017-09-01

The choice of inodilator drug in the acute management of patients with pulmonary hypertension (PH) having right ventricular (RV) failure remains unsettled and challenging. Comprehensive experimental evaluations may provide further insight and fundamental translational research clues to support inodilator selection and clinical trial design. Our aim was to compare acute dose-response hemodynamic effects of inodilators dobutamine (DOB), milrinone (MIL), and levosimendan (LEV) in chronic experimental PH. Seven-week-old male Wistar rats were randomly injected with 60 mg·kg -1 monocrotaline (MCT) or vehicle (Ctrl, n = 7) and underwent systemic and pulmonary artery (PA) pressure and RV pressure-volume (PV) hemodynamic evaluation under halogenate anesthesia 24 to 30 days after injection. The MCT-injected animals (n = 7 each) randomly received dose-response infusions of DOB (1, 3, 6 and 12 μg·kg -1 ·min -1 ), MIL (MIL: 1, 3, 6 and 12 μg·kg -1 ·min -1 ), or LEV (0.3, 0.6, 1.2 and 2.4 μg·kg -1 ·min -1 ). Load-independent indexes were obtained by inferior vena cava occlusion at baseline and after the last dose. All inodilators increased RV ejection fraction, preload recruitable stroke work, and ventricular-vascular coupling without jeopardizing perfusion pressure. Dobutamine raised heart rate and PA pressure. Only LEV increased cardiac index and decreased PA elastance and pulmonary vascular resistance (PVR). Moreover, only LEV downward-shifted the end-diastolic PV relationship, thereby improving RV compliance. Adding sildenafil to LEV further decreased PVR. Levosimendan had beneficial acute systolic and diastolic functional effects in experimental chronic PH and RV afterload compared to DOB and MIL. It should be further tested in clinical trials enrolling patients with PH in the perioperative and critical care settings.

Unique behavioral characteristics and microRNA signatures in a drug resistant epilepsy model.

Directory of Open Access Journals (Sweden)

Jangsup Moon

Full Text Available BACKGROUND: Pharmacoresistance is a major issue in the treatment of epilepsy. However, the mechanism underlying pharmacoresistance to antiepileptic drugs (AEDs is still unclear, and few animal models have been established for studying drug resistant epilepsy (DRE. In our study, spontaneous recurrent seizures (SRSs were investigated by video-EEG monitoring during the entire procedure. METHODS/PRINCIPAL FINDINGS: In the mouse pilocarpine-induced epilepsy model, we administered levetiracetam (LEV and valproate (VPA in sequence. AED-responsive and AED-resistant mice were naturally selected after 7-day treatment of LEV and VPA. Behavioral tests (open field, object exploration, elevated plus maze, and light-dark transition test and a microRNA microarray test were performed. Among the 37 epileptic mice with SRS, 23 showed significantly fewer SRSs during administration of LEV (n = 16, LEV sensitive (LS group or VPA (n = 7, LEV resistant/VPA sensitive (LRVS group, while 7 epileptic mice did not show any amelioration with either of the AEDs (n = 7, multidrug resistant (MDR group. On the behavioral assessment, MDR mice displayed distinctive behaviors in the object exploration and elevated plus maze tests, which were not observed in the LS group. Expression of miRNA was altered in LS and MDR groups, and we identified 4 miRNAs (miR-206, miR-374, miR-468, and miR-142-5p, which were differently modulated in the MDR group versus both control and LS groups. CONCLUSION: This is the first study to identify a pharmacoresistant subgroup, resistant to 2 AEDs, in the pilocarpine-induced epilepsy model. We hypothesize that modulation of the identified miRNAs may play a key role in developing pharmacoresistance and behavioral alterations in the MDR group.

Phenotypic and genetic characteristics of fluoroquinolone- and methicillin-resistant Staphylococcus aureus.

Science.gov (United States)

Moreno-Flores, Antonio; Potel-Alvarellos, Carmen; Otero-Fernández, Susana; Álvarez-Fernández, Maximiliano

2017-07-20

Fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus (MRSA) has increased in recent years. The objective of this study was to characterise two MRSA populations, one susceptible to fluoroquinolones and other resistant identifying the clonal types and the differential characteristics of both MRSA populations. Molecular typing using PFGE, MLST, spa and SSCmec was performed on 192 MRSA strains isolated from 2009 to 2011, 49 only oxacillin-resistant (OX-R) and 143 oxacillin and levofloxacin-resistant (OX-R-LEV-R). Mutations that conferred resistance to fluoroquinolones, hypermutable phenotypes and the presence of eight microbial surface components recognising adhesive matrix molecules (MSCRAMMs) were also studied. A statistically significant increase in the OX-R-LEV-R phenotype was observed (p<0.05). The most common clone of the OX-R isolates was sequence type (ST) 8 (32.6%), followed by ST72 (26.5%) and ST5 (26.5%). In the OX-R-LEV-R phenotype, the ST5 clone was the most common (65.7%), followed by ST72 (15.4%), and ST125 (12.6%). All isolates except the ST398 clone carried the SCCmecIVc. Clones ST5, ST72, ST125, and ST30 had hypermutable phenotypes. The ST72 clone and the ST30 clone in the OX-R phenotype harboured the highest number of MSCRAMMs. ST5 and ST72 clones were the most frequent clones identified in OX-R-LEV-R phenotype. Both clones showed a hypermutable phenotype that favours their selection as the fluoroquinolone resistant clones. The genetic relationships identified indicate that OX-R-LEV-R clones have evolved from OX-R MRSA clones. Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

Brivaracetam: a novel antiepileptic drug for focal-onset seizures.

Science.gov (United States)

Stephen, Linda J; Brodie, Martin J

2018-01-01

Brivaracetam (BRV), the n -propyl analogue of levetiracetam (LEV), is the latest antiepileptic drug (AED) to be licensed in Europe and the USA for the adjunctive treatment of focal-onset seizures with or without secondary generalization in patients aged 16 years or older. Like LEV, BRV binds to synaptic vesicle protein 2A (SV2A), but BRV has more selective binding and a 15- to 30-fold higher binding affinity than LEV. BRV is more effective than LEV in slowing synaptic vesicle mobilization and the two AEDs may act at different binding sites or interact with different conformational states of the SV2A protein. In animal models, BRV provides protection against focal and secondary generalized seizures and has significant anticonvulsant effects in genetic models of epilepsy. The drug undergoes first-order pharmacokinetics with an elimination half-life of 7-8 h. Although BRV is metabolized extensively, the main circulating compound is unchanged BRV. Around 95% of metabolites undergo renal elimination. No dose reduction is required in renal impairment, but it is recommended that the daily dose is reduced by one-third in hepatic dysfunction that may prolong half-life. BRV has a low potential for drug interactions. The efficacy and tolerability of adjunctive BRV in adults with focal-onset seizures have been explored in six randomized, placebo-controlled studies. These showed significant efficacy outcomes for doses of 50-200 mg/day. The most common adverse events reported were headache, somnolence, dizziness, fatigue and nausea. Patients who develop psychiatric symptoms with LEV appear to be at risk of similar side effects with BRV, although preliminary data suggest that these issues are likely to be less frequent and perhaps less severe. As with all AEDs, a low starting dose and slow titration schedule help to minimize side effects and optimize seizure control and thereby quality of life.

Dépression et niveau de fardeau chez les aidants familiaux des sujets déments en Tunisie

Science.gov (United States)

Ben Thabet, Jihène; Jaoua, Feriel; Charfi, Nada; Zouari, Lobna; Zouari, Nasreddine; Maalej, Mohamed

2011-01-01

Introduction La démence peut retentir lourdement sur les aidants familiaux du patient. Les objectifs de notre étude étaient de déterminer le niveau de fardeau et de la dépression chez les aidants familiaux de sujets déments, et d'identifier les facteurs associés à un niveau de fardeau élevé. Méthodes Il s'agissait d'une enquête auprès de 65 aidants tunisiens. Les niveaux de fardeau et de la dépression ont été évalués par, respectivement, l'inventaire de Zarit et l’échelle de Beck. Résultats Le taux des aidants qui avaient un niveau de fardeau élevé était de 52,3 %. Une dépression modérée ou sévère a été relevée chez 46,2 %. Un niveau de fardeau élevé était corrélé, du côté de l'aidant, avec le niveau socio-économique moyen à élevé, la cohabitation avec le patient, le fait d’être son conjoint, la réduction des activités quotidiennes et la sévérité de la dépression, et, du côté du dément, avec l'agressivité. Conclusion Les facteurs corrélés à un niveau de fardeau élevé orientent vers les cibles d'intervention et sont susceptibles d’être améliorés par la prise en charge, ce qui contribuerait à alléger la détresse des aidants. PMID:22384291

Cardiovascular disease risk factors in 5-year-old urban South ...

African Journals Online (AJOL)

Cardiovascular disease risk factors in 5-year-old urban South African children the birth to ten study. Krisela Steyn, Thea de Wet, Linda Richter, Noel Cameron, Naomi S Levitt, Christopher Morrell ...

Using communication skills for difficult conversations in palliative care

African Journals Online (AJOL)

2011-07-02

Jul 2, 2011 ... research interests in primary palliative care and medical education. LINDa gaNca ... professional nurse administers medication and gives nursing care, the social worker .... future communication in the therapeutic relationship.

Koguteos ristisõjaliikumisest / Maiki Voore

Index Scriptorium Estoniae

Voore, Maiki, 1983-

2011-01-01

Tutvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

Alguses oli Henrik / Juhan Kreem

Index Scriptorium Estoniae

Kreem, Juhan, 1971-

2012-01-01

Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

Henriku uurimise hetkeseis / Mihkel Mäesalu

Index Scriptorium Estoniae

Mäesalu, Mihkel, 1985-

2011-01-01

Tutvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

Mõttesügav ajalooteos / Enn Tarvel

Index Scriptorium Estoniae

Tarvel, Enn, 1932-

2012-01-01

Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

Koguteos ristisõdadest Läänemere idarannikul

Index Scriptorium Estoniae

2011-01-01

Tutvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington : Ashgate, 2011

Mentoring in Nursing: A Historical Approach.

Science.gov (United States)

Fields, Willa L.

1991-01-01

Nursing leaders such as Florence Nightingale, Linda Richards, Mary Adelaide Nutting, and Annie Goodrich were all encouraged by mentors to develop professionally. Most successful professionals have had at least one mentor. (SK)

Earthquake and ambient vibration monitoring of the steel-frame UCLA factor building

Science.gov (United States)

Kohler, M.D.; Davis, P.M.; Safak, E.

2005-01-01

Dynamic property measurements of the moment-resisting steel-frame University of California, Los Angeles, Factor building are being made to assess how forces are distributed over the building. Fourier amplitude spectra have been calculated from several intervals of ambient vibrations, a 24-hour period of strong winds, and from the 28 March 2003 Encino, California (ML = 2.9), the 3 September 2002 Yorba Linda, California (ML = 4.7), and the 3 November 2002 Central Alaska (Mw = 7.9) earthquakes. Measurements made from the ambient vibration records show that the first-mode frequency of horizontal vibration is between 0.55 and 0.6 Hz. The second horizontal mode has a frequency between 1.6 and 1.9 Hz. In contrast, the first-mode frequencies measured from earthquake data are about 0.05 to 0.1 Hz lower than those corresponding to ambient vibration recordings indicating softening of the soil-structure system as amplitudes become larger. The frequencies revert to pre-earthquake levels within five minutes of the Yorba Linda earthquake. Shaking due to strong winds that occurred during the Encino earthquake dominates the frequency decrease, which correlates in time with the duration of the strong winds. The first shear wave recorded from the Encino and Yorba Linda earthquakes takes about 0.4 sec to travel up the 17-story building. ?? 2005, Earthquake Engineering Research Institute.

Efficacy of levetiracetam in primary hemifacial spasm.

Science.gov (United States)

Kuroda, Takeshi; Saito, Yu; Fujita, Kazuhisa; Yano, Satoshi; Ishigaki, Seiichiro; Kato, Hirotaka; Murakami, Hidetomo; Ono, Kenjiro

2016-12-01

Hemifacial spasm (HFS) is a peripherally-induced movement disorder characterized by the involuntary, unilateral, intermittent, irregular, tonic or clonic contractions of muscles innervated by the ipsilateral facial nerve. Kindling-like hyperactivity of the facial nucleus induced by constant stimulation of compressing artery is considered as the predominant mechanism underlying the pathogenesis of HFS. As a treatment for HFS, microsurgical decompression and botulinum toxin injection have been shown to be highly successful. Anticonvulsant drugs relieve HFS in some patients; however, the use of such drugs is limited owing to their side effects, predominantly in elderly patients. We experienced two elderly HFS patients who exhibited a marked response to levetiracetam (LEV) without side effects. Although the exact underlying pharmacological mechanism remains unknown, we assume anti-kindling effect as one of the important pharmacological mechanism underlying the effect of LEV against HFS. Moreover, LEV is considered to be suitable for use in elderly patients because of its good tolerability. In addition, the lack of hepatic induction or inhibition makes it an easy and safe drug when used in addition to other anticonvulsants. Although the long-term benefit remains unknown, LEV may represent an alternative treatment for elderly HFS patients who are unable to undergo or decline surgical intervention and/or botulinum toxin injections or are intolerant to other anticonvulsants. Copyright © 2016 Elsevier Ltd. All rights reserved.

A Rapid, Simple, and Validated RP-HPLC Method for Quantitative Analysis of Levofloxacin in Human Plasma

Directory of Open Access Journals (Sweden)

Dion Notario

2017-04-01

Full Text Available To conduct a bioequivalence study for a copy product of levofloxacin (LEV, a simple and validated analytical method was needed, but the previous developed methods were still too complicated. For this reason, a simple and rapid high performance liquid chromatography method was developed and validated for LEV quantification in human plasma. Chromatographic separation was performed under isocratic elution on a Luna Phenomenex® C18 (150 × 4.6 mm, 5 µm column. The mobile phase was comprised of acetonitrile, methanol, and phosphate buffer 25 mM that adjusted at pH 3.0 (13:7:80 v/v/v and pumped at a flow rate of 1.5 mL/min. Detection was performed under UV detector at wavelength of 280 nm. Samples were prepared by adding acetonitrile and followed by centrifugation to precipitate plasma protein. Then followed successively by evaporation and reconstitution step. The optimized method meets the requirements of validation parameters which included linearity (r = 0.995, sensitivity (LLOQ and LOD was 1.77 and 0.57 µg/mL respectively, accuracy (%error above LLOQ ≤ 12% and LLOQ ≤ 20%, precision (RSD ≤ 9%, and robustness in the ranges of 1.77-28.83 µg/mL. Therefore, the method can be used as a routine analysis of LEV in human plasma as well as in bioequivalence study of LEV.

Microwave-assisted synthesis of highly luminescent N- and S-co-doped carbon dots as a ratiometric fluorescent probe for levofloxacin.

Science.gov (United States)

Li, Huiyu; Xu, Yuan; Ding, Jie; Zhao, Li; Zhou, Tianyu; Ding, Hong; Chen, Yanhua; Ding, Lan

2018-01-10

Uniform N- and S-co-doped carbon dots (NSCDs) with fluorescence quantum yields of up to 64% were synthesized via a one-step microwave-assisted method. Ammonium citrate and L-cysteine act as precursors, and synthesis is completed in 2.5 min using a 750 W microwave oven to give a 62% yield. The NSCDs show bright blue fluorescence (with excitation/emission peaks at 353/426 nm) and have narrow size distribution. On exposure to levofloxacin (LEV), the emission maximum shifts to 499 nm. This effect was used to design ratiometric (2-wavelength) assays for LEV. The fluorometric method (based on measurement of the fluorescence intensity ratio at 499 and 426 nm) has a detection limit of 5.1 μg·L -1 (3σ/k) and a linear range that extends from 0.01 to 70 mg·L -1 . The method was applied to the determination of LEV in three kinds of spiked water samples and has recoveries in the range from 98.6 to 106.8%. The fluorescent probe described here is highly selective and sensitive. Graphical Abstract Highly luminescent N- and S-co-doped carbon dots were synthesized using AC (ammonium citrate) and Cys (L-cysteine) by microwave-assisted method, and were applied to the visual and ratiometric fluorescence determination of LEV (levofloxacin).

Roughness Effects on the Formation of a Leading Edge Vortex

Science.gov (United States)

Elliott, Cassidy; Lang, Amy; Wahidi, Redha; Wilroy, Jacob

2016-11-01

Microscopic scales cover the wings of Monarch butterflies, creating a patterned surface. This patterning is an important natural flow control mechanism that is thought to delay the growth of the leading edge vortex (LEV) produced by the flapping motion of a wing. The increased skin friction caused by the scales leads to a weaker LEV being shed into the butterfly's wake, lessening drag and increasing flight efficiency. To test this theory, a plate of random roughness was designed in SolidWorks and printed on the Objet 30 Pro 3D printer. A 2x3x5 cubic foot tow tank was used to test the rough plate at Reynold's numbers of 1500, 3000, and 6000 (velocities of 8, 16, and 32 mm/s) at an angle of attack of 45 degrees. Particle Image Velocimetry (PIV) captured images of the LEV generated by the plate when towed upwards through the particle-seeded flow. Codes written in MatLab were used to automatically track and determine the strength of the LEV. Circulation values for the randomly-rough plate were then compared to the same values generated in a previous experiment that used a smooth plate and a grooved plate to determine the effect of the patterning on vortex development. Funding provided by NSF REU site Grant EEC 1358991 and CBET 1628600.

Observing and Modelling the HighWater Level from Satellite Radar Altimetry During Tropical Cyclones

DEFF Research Database (Denmark)

Deng, Xiaoli; Gharineiat, Zahra; Andersen, Ole Baltazar

2016-01-01

This paper investigates the capability of observing tropical cyclones using satellite radar altimetry. Two representative cyclones Yasi (February 2011) and Larry (March 2006) in the northeast Australian coastal area are selected based also on available tide gauge sea level measurements. It is sho...

77 FR 71873 - Disciplinary Appeals Board Panel

Science.gov (United States)

2012-12-04

... review and comment. Employees, employee organizations, and other interested parties shall be provided... CONTACT: Larry Ables, Employee Relations and Performance Management Service (051), Office of Human.... Ables may be reached at (202) 461-6172. SUPPLEMENTARY INFORMATION: Public Law 102-40 requires that the...

Principles of Building Partnership Capacity

Science.gov (United States)

2010-06-11

COCOM and the green container that represents the COCOMs ability to influence the overall size of the engagement. United States BPC Efforts...1977. Japanese foreign policy 1869-1942: Kasumigaseki to Miyakezaka. Boston MA: Routledge and Kegan Paul Ltd. Nowes, Larry. 2006. Congressional

77 FR 12629 - Self-Regulatory Organizations; New York Stock Exchange LLC; NYSE Amex LLC; Notice of Filing of...

Science.gov (United States)

2012-03-01

..., Themis Trading LLC, dated October 17, 2011 (``Themis Letter''); Garret Cook, dated November 4, 2011 (``Cook Letter''); James Johannes, dated November 27, 2011 (``Johannes Letter''); Ken Voorhies, dated... (``UBS Letter''); Dr. Larry Paden, Bright Trading, dated December 1, 2011 (``Paden Letter''); Thomas...

Probability theory: the logic of science

National Research Council Canada - National Science Library

Jaynes, E. T; Bretthorst, G. Larry

2005-01-01

... by G. Larry Bretthorst Copyright   Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo Cambridge University Press...

77 FR 60207 - Endangered and Threatened Wildlife and Plants; Proposed Threatened Status for Coral Pink Sand...

Science.gov (United States)

2012-10-02

... FURTHER INFORMATION CONTACT: Larry Crist, Field Supervisor, U.S. Fish and Wildlife Service, Utah Field... burrows, dune migration characteristics that permit vegetation to develop and persist within dune swales... sediment characteristics not conducive for vegetation nor suitable for larval burrows, dune migration...

[Crusading and chronicle writing on the medieval Baltic frontier: A companion to the chronicle of Henry of Livonia] / Radosław Biskup

Index Scriptorium Estoniae

Biskup, Radosław

2014-01-01

Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the chronicle of Henry of Livonia, eds. Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington (Vt.) : Ashgate, c2011

Etude de la diversité morphométrique de deux populations d ...

African Journals Online (AJOL)

Une étude biométrique a été réalisée sur des abeilles ouvrières domestiques prélevées dans 07 sites et sur 11 ruchers du Sud algérien situés dans les étages bioclimatiques aride (wilaya Laghouat) et saharien (wilaya Béchar). Sur chaque site, entre 45 et 60 abeilles ont été prélevées aléatoirement, soit un total de 567 ...

Kuu plaat : Frida Hyvönen "Hyvönen". Plaadid kauplusest Lasering

Index Scriptorium Estoniae

2006-01-01

Heliplaatidest: Linda Hyvönen "Until Death Comes", Pia Fraus "Nature Heart Software", Weekend Guitar Trio "Lava", Arctic Monkeys "Whatever People Say I Am, That's What I'm Not", Blacky "See on me meeltele"

Prescott’s Microbiology, Eighth Edition

OpenAIRE

Dobbins, Joanne J.

2010-01-01

Review of: Prescott’s Microbiology, Eighth Edition. Joanne M. Willey, Linda M. Sherwood, and Christopher J. Woolverton. 2011. McGraw-Hill Higher Education, NewYork, NY. 1070 pages. ISBN- 978-0-07-337526-7.

Learn to love exercise

Science.gov (United States)

... well, such as tickets to a concert or movie. Alternative Names Prevention - learn to love exercise; Wellness - ... 23630089 www.ncbi.nlm.nih.gov/pubmed/23630089 . Review Date 5/21/2016 Updated by: Linda J. ...

Visualization of SV2A conformations in situ by the use of Protein Tomography

International Nuclear Information System (INIS)

Lynch, Berkley A.; Matagne, Alain; Braennstroem, Annika; Euler, Anne von; Jansson, Magnus; Hauzenberger, Elenor; Soederhaell, J. Arvid

2008-01-01

The synaptic vesicle protein 2A (SV2A), the brain-binding site of the anti-epileptic drug levetiracetam (LEV), has been characterized by Protein Tomography TM . We identified two major conformations of SV2A in mouse brain tissue: first, a compact, funnel-structure with a pore-like opening towards the cytoplasm; second, a more open, V-shaped structure with a cleft-like opening towards the intravesicular space. The large differences between these conformations suggest a high degree of flexibility and support a valve-like mechanism consistent with the postulated transporter role of SV2A. These two conformations are represented both in samples treated with LEV, and in saline-treated samples, which indicates that LEV binding does not cause a large-scale conformational change of SV2A, or lock a specific conformational state of the protein. This study provides the first direct structural data on SV2A, and supports a transporter function suggested by sequence homology to MFS class of transporter proteins

Real-time black carbon emission factor measurements from light duty vehicles.

Science.gov (United States)

Forestieri, Sara D; Collier, Sonya; Kuwayama, Toshihiro; Zhang, Qi; Kleeman, Michael J; Cappa, Christopher D

2013-11-19

Eight light-duty gasoline low emission vehicles (LEV I) were tested on a Chassis dynamometer using the California Unified Cycle (UC) at the Haagen-Smit vehicle test facility at the California Air Resources Board in El Monte, CA during September 2011. The UC includes a cold start phase followed by a hot stabilized running phase. In addition, a light-duty gasoline LEV vehicle and ultralow emission vehicle (ULEV), and a light-duty diesel passenger vehicle and gasoline direct injection (GDI) vehicle were tested on a constant velocity driving cycle. A variety of instruments with response times ≥0.1 Hz were used to characterize how the emissions of the major particulate matter components varied for the LEVs during a typical driving cycle. This study focuses primarily on emissions of black carbon (BC). These measurements allowed for the determination of BC emission factors throughout the driving cycle, providing insights into the temporal variability of BC emission factors during different phases of a typical driving cycle.

OHD/HL - RFCDEV/HVT: 2nd charter

Science.gov (United States)

success criteria defined here no later than September 30, 2011. No travel beyond a RFC verification /HSD) Larry Lowe (ABRFC verification focal point) James Coe (APRFC verification focal point) Ashley Nielson (CBRFC verification focal point) Kevin Werner (CBRFC verification co-focal point and SCH

Genetic structure of Pseudococcus microcirculus (Hemiptera ...

Indian Academy of Sciences (India)

Department of Biology, Armstrong State University, Savannah, GA 31419, USA. Abstract ... [Zettler J. A., Adams K., Frederick B., Gutting A., Ingebretsen N., Ragsdale A. and Schrey A. 2017 Genetic structure of Pseudococcus ..... Park) and Larry Richardson (Florida Panther Wildlife Refuge) for ... University Press of Florida,.

CrossTalk: The Journal of Defense Software Engineering. Volume 24, Number 1, Jan/Feb 2011

Science.gov (United States)

2011-02-01

Aircraft Sustainment Group Tony Henderson 309th Software Maintenance Group Lt. Col. Brian Hermann, Ph.D. Defense Information Systems Agency Lt. Col...Solutions, Inc. Gordon Sleve Robbins Gioia LLC Larry Smith Software Technology Support Center Dr. John Sohl Weber State University Elizabeth Starrett OO-ALC

The National Shipbuilding Research Program: Solid Waste Segregation and Recycling

Science.gov (United States)

1998-03-01

decreasing landfill space, legislated recycling goals are being set, and your institution is expected to comply. The letter indicates that all...Larry Krull, (800) 837-3398, landfill covers, liners, and cap systems Canadian Forest Products, Ltd., New Westminister , BC, Joe Hargitt, (604) 520-9327

Stronger Consistency and Semantics for Low-Latency Geo-Replicated Storage

Science.gov (United States)

2013-06-01

Wallach, Mike Burrows , Tushar Chandra, Andrew Fikes, and Robert E. Gruber. Bigtable: A distributed storage system for structured data. ACM TOCS, 26(2...propagation for weakly consistent replication. In SOSP, October 1997. [60] Larry Peterson, Andy Bavier, and Sapan Bhatia. VICCI: A programmable cloud

75 FR 30338 - Endangered and Threatened Wildlife and Plants; 12-month Finding on a Petition to List the White...

Science.gov (United States)

2010-06-01

... concerning this finding to the above street address. FOR FURTHER INFORMATION CONTACT: Larry Crist, Field... actively work to maintain the grassland vegetation surrounding their burrows for visibility. White-tailed prairie dogs dig their own burrows. Burrow construction requires deep, well-drained soils. Preferred soils...

78 FR 61081 - Endangered and Threatened Wildlife and Plants; Withdrawal of the Proposed Rule To List Coral Pink...

Science.gov (United States)

2013-10-02

... facsimile 801-975-3331. FOR FURTHER INFORMATION CONTACT: Larry Crist, Field Supervisor, Utah Ecological... vegetation, swale sediment characteristics appropriate for vegetation and larval burrows, dune migration... by the female within the burrows that tiger beetles typically dig during the hot part of the day and...

Trading Freshness for Performance in Distributed Systems

Science.gov (United States)

2014-12-01

C. Hsieh, Deborah A. Wallach, Mike Burrows , Tushar Chandra, Andrew Fikes, and Robert E. Gruber. BigTable: A distributed storage system for structured... Larry Brilliant. Detecting influenza epidemics using search engine query data. Nature, pages 1012–1014, February 2009. 3.2 Goetz Graefe. Write

Forms of Arthritis

Science.gov (United States)

... this page please turn Javascript on. Forms of Arthritis Past Issues / Fall 2006 Table of Contents Today, ... of Linda Saisselin Osteoarthritis (OA) — the form of arthritis typically occurring during middle or old age, this ...

Download this PDF file

African Journals Online (AJOL)

This study was approved by the Loma Linda University. Institutional Review Board (IRB) ... about exclusive breastfeeding, he encouraged me to follow the instructions. .... Women also cited the benefits of adhering to exclusive breastfeeding for ...

78 FR 40738 - Proposed CERCLA Administrative Cost Recovery Settlement; Double H Pesticide Burial Site

Science.gov (United States)

2013-07-08

... are Double H, L.P.; James T. Hansen; Linda L. Hansen; George W. Higgins; and Edith M. Higgins. The... their original terms. Dated: June 27, 2013. Chris D. Field, Manager, Emergency Management Program, U.S...

77 FR 67671 - Larry Elbert Perry, M.D.; Decision and Order

Science.gov (United States)

2012-11-13

... June 7, 2012, the Government filed a Motion for Stay of Proceedings and Summary Disposition (``MSD... proceedings pending the results of this Government motion.'' MSD, at 5. A copy of a November 19, 2009...'s surrender of his state license to practice medicine, were both attached to the MSD. The Respondent...

827-IJBCS-Article-Elisabeth Yehouenou

African Journals Online (AJOL)

DR GATSING

La zone nord est surélevée par rapport à la zone sud. Taux de métaux lourds dans le sol. La Figure 1 montre la teneur en métaux lourds dans les échantillons de sols prélevés aussi bien du côté sud que du côté nord du site. Il en ressort que lesdits sols sont contaminés par des métaux toxiques comme le zinc, le chrome, le ...

Caractérisation physico-chimique et diversité du peuplement ...

African Journals Online (AJOL)

faits au microscope photonique de marque Nikon Eclipse 0,90 Dry. L'étude a révélé une turbidité, un pH et un taux d'oxygène dissous élevés dans les mares Afi et Lagoè avec des valeurs maximales de 8,25 NTU ; 8,14 et. 9,75 mg/L. A Dindin, une conductivité électrique élevée de 590 µS/cm et un taux d'oxydabilité au ...

Rahvusooper Estonia interjööride renoveerimine = Renovation of the Estonia National Opera House interiors

Index Scriptorium Estoniae

2007-01-01

2006. a. lõpetati Rahvusooperi Estonia publikuruumide renoveerimine. Sisearhitektid Juta Lember ja Aulo Padar. Siseviimistluse ja laemaali (E. Okas, E. Kits, R. Sagrits) restaureerimine ja konserveerimine: KAR Grupp. Akustik Linda Madalik. 8 värv. vaadet

Keep the Blood Flowing (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

Cardiovascular disease accounts for more than 800,000 deaths each year in the U.S. Fortunately, many are preventable by following a few simple strategies. In this podcast, Linda Schieb discusses ways to prevent cardiovascular disease.

Current Writing: Text and Reception in Southern Africa - Vol 18, No 1 ...

African Journals Online (AJOL)

Lions, leopards and liminal spaces:Representations of Biosociality in the Writings of Katy Payne, Linda Tucker and Gillian van Houten · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. W Woodward ...

Vehicle Dynamics due to Magnetic Launch Propulsion

Science.gov (United States)

Galaboff, Zachary J.; Jacobs, William; West, Mark E.; Montenegro, Justino (Technical Monitor)

2000-01-01

The field of Magnetic Levitation Lind Propulsion (MagLev) has been around for over 30 years, primarily in high-speed rail service. In recent years, however, NASA has been looking closely at MagLev as a possible first stage propulsion system for spacecraft. This approach creates a variety of new problems that don't currently exist with the present MagLev trains around the world. NASA requires that a spacecraft of approximately 120,000 lbs be accelerated at two times the acceleration of gravity (2g's). This produces a greater demand on power over the normal MagLev trains that accelerate at around 0.1g. To be able to store and distribute up to 3,000 Mega Joules of energy in less than 10 seconds is a technical challenge. Another problem never addressed by the train industry and, peculiar only to NASA, is the control of a lifting body through the acceleration of and separation from the MagLev track. Very little is understood about how a lifting body will react with external forces, Such as wind gusts and ground effects, while being propelled along on soft springs such as magnetic levitators. Much study needs to be done to determine spacecraft control requirements as well as what control mechanisms and aero-surfaces should be placed on the carrier. Once the spacecraft has been propelled down the track another significant event takes place, the separation of the spacecraft from the carrier. The dynamics involved for both the carrier and the spacecraft are complex and coupled. Analysis of the reaction of the carrier after losing, a majority of its mass must be performed to insure control of the carrier is maintained and a safe separation of the spacecraft is achieved. The spacecraft angle of attack required for lift and how it will affect the carriage just prior to separation, along with the impacts of around effect and aerodynamic forces at ground level must be modeled and analyzed to define requirements on the launch vehicle design. Mechanisms, which can withstand the

Accelerating Project and Process Improvement using Advanced Software Simulation Technology: From the Office to the Enterprise

Science.gov (United States)

2010-04-29

Technology: From the Office Larry Smith Software Technology Support Center to the Enterprise 517 SMXS/MXDEA 6022 Fir Avenue Hill AFB, UT 84056 801...2010 to 00-00-2010 4. TITLE AND SUBTITLE Accelerating Project and Process Improvement using Advanced Software Simulation Technology: From the Office to

Anatomy Journal of Africa - Vol 4, No 2 (2015)

African Journals Online (AJOL)

Variant Anatomy of Intracranial Part of Middle Meningeal Artery in a Kenyan Population · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Julius Ogeng'o, Beda Olabu, Mary I. Otiti, Beryl S. Ominde, Larry Mburu, Hemed Elbusaidy, 571-577 ...

A NOVEL S-ADENOSYL-L-METHIONINE: ARSENIC (III) METHYLTRANSFERASE FROM RAT LIVER CYTOSOL

Science.gov (United States)

A Novel S-Adenosyl-L-methionine: Arsenic(III) Methyltransferase from Rat Liver CytosolShan Lin, Qing Shi, F. Brent Nix, Miroslav Styblo, Melinda A. Beck, Karen M. Herbin-Davis, Larry L. Hall, Josef B. Simeonsson, and David J. Thomas S-adenosyl-L-methionine (AdoMet): ar...

The Social Organization of Schooling

Science.gov (United States)

Hedges, Larry V., Ed.; Schneider, Barbara, Ed.

2005-01-01

Schools are complex social settings where students, teachers, administrators, and parents interact to shape a child's educational experience. Any effort to improve educational outcomes for America's children requires a dynamic understanding of the environments in which children learn. In "The Social Organization of Schooling", editors Larry Hedges…

Artificial Intelligence in ADA: Pattern-Directed Processing. Final Report.

Science.gov (United States)

Reeker, Larry H.; And Others

To demonstrate to computer programmers that the programming language Ada provides superior facilities for use in artificial intelligence applications, the three papers included in this report investigate the capabilities that exist within Ada for "pattern-directed" programming. The first paper (Larry H. Reeker, Tulane University) is…

A Trend Analysis: Rising Threshold for China to Use Force in Territorial Disputes in South and East China Seas

Science.gov (United States)

2012-12-01

31 Michael McDevitt, “Geographic Ruminations ,” in The Chinese Armed Forces in 21st Century, ed. Larry M. Wortzel, (Carlisle, Pennsylvania...Philippines and Vietnam remained as main contenders in the region. Admittedly, the U.S. strategic re-orientation toward Asia and its enhancing security

"To Kill A Mockingbird": Then and Now--A 35th Anniversary Celebration. Teacher Study Guide.

Science.gov (United States)

National Council of Teachers of English, Urbana, IL.

This study guide offers a different approach, teleconferencing, to new information, ideas, and resources on the film, "To Kill a Mockingbird." Following general information on "then and now," the guide consists of sections entitled: Preparing to Teach TKM: Special Considerations (by Charles Suhor and Larry Bell); Historical…

Overvågning som lovgivning

DEFF Research Database (Denmark)

Simonsen, Karen-Margrethe

2010-01-01

Artiklen handler om overvågning i to kunstværker, hhv. Hasan Elahis "Tracking Transience" og Surveillance Camera Players "1984". Den diskuterer overvågningens form, materialitet og det implicitte tema om individets retsstatus. Med udgangspunkt i Gilles Deleuze og juristen Larry Catá Backer...

Ultrahigh Vacuum Studies of the Fundamental Interactions of Chemical Warfare Agents and Their Simulants with Amorphous Silica

Science.gov (United States)

2015-07-14

realize and my success in graduate school began with their mentorship. Erin Davis, Jessica Lu, Will Alexander, Steve Burrows , Alec Wagner, Yafen...description of the doser can be found in Larry Fiegland’s dissertation.68 The second doser is a variable sapphire-plate precision leak valve (Duniway

Strategic Improvements to TSA Spot Program

Science.gov (United States)

2015-03-01

supporting me in this program, and specifically, Assistant Administrators Robin Kane, John Sanders, and Chris McLaughlin for their sponsorship. I hope...analysis. Edited by Michael Borenstein, Larry V. Hedges, Julian P. T. Higgins , and Hannah R. Rothstein, 377–387. Chichester, UK: John Wiley & Sons, 2009

Forewings match the formation of leading-edge vortices and dominate aerodynamic force production in revolving insect wings.

Science.gov (United States)

Chen, Di; Kolomenskiy, Dmitry; Nakata, Toshiyuki; Liu, Hao

2017-10-20

In many flying insects, forewings and hindwings are coupled mechanically to achieve flapping flight synchronously while being driven by action of the forewings. How the forewings and hindwings as well as their morphologies contribute to aerodynamic force production and flight control remains unclear yet. Here we demonstrate that the forewings can produce most of the aerodynamic forces even with the hindwings removed through a computational fluid dynamic study of three revolving insect wing models, which are identical to the wing morphologies and Reynolds numbers of hawkmoth (Manduca sexta), bumblebee (Bombus ignitus) and fruitfly (Drosophila melanogaster). We find that the forewing morphologies match the formation of leading-edge vortices (LEV) and are responsible for generating sufficient lift forces at the mean angles of attack and the Reynolds numbers where the three representative insects fly. The LEV formation and pressure loading keep almost unchanged with the hindwing removed, and even lead to some improvement in power factor and aerodynamic efficiency. Moreover, our results indicate that the size and strength of the LEVs can be well quantified with introduction of a conical LEV angle, which varies remarkably with angles of attack and Reynolds numbers but within the forewing region while showing less sensitivity to the wing morphologies. This implies that the forewing morphology very likely plays a dominant role in achieving low-Reynolds number aerodynamic performance in natural flyers as well as in revolving and/or flapping micro air vehicles. © 2017 IOP Publishing Ltd.

As margens plácidas de O quinto dos infernos

Directory of Open Access Journals (Sweden)

Renato Luiz Pucci Junior

2003-06-01

Full Text Available The serial O Quinto dos Infernos is compared with the film Carlota Joaquina, Princesa do Brazil, in order to point out, in Linda Hutcheon' s sense, some postmodernist traces and its unaccomplished historiographic metafiction.

Go4Life

Medline Plus

Full Text Available ... 2 minutes, 48 seconds. National Institute On Aging 12,023 views 5 years ago CC 2:27 ... seconds. National Institute On Aging 5 years ago 12,760 views Trainer Sandy shows Linda how to ...

Go4Life

Medline Plus

Full Text Available ... 2 minutes, 48 seconds. National Institute On Aging 12,220 views 6 years ago CC 2:27 ... seconds. National Institute On Aging 6 years ago 12,952 views Trainer Sandy shows Linda how to ...

Individual reports : Finland : 1992-1998

Index Scriptorium Estoniae

1999-01-01

EMKÜ presidendi Avo Kartuli külaskäigust Soome raamatukogudesse 1992. aastal ja Eesti Rahvusraamatukogu Kunstide Teabekeskuse töötajate Aurika Gergelezhiu ja Linda Tõnissoni külaskäigust vastavalt 1993. ja 1998. aastal

Pärnu uue kunsti muuseumis...

Index Scriptorium Estoniae

2004-01-01

Ungari keraamikute Marta Nagy ja György Kungli näitus "Echo", rootsi outsider-kunstnike Linda Perssoni ja Buster Hollingworthi maalinäitus, Konstantin Tabanakovi fotonäitus "Pärnu tšetšeeni silmadega"

Raamat eesti naiste saatustest / Ülo Ignats

Index Scriptorium Estoniae

Ignats, Ülo, 1951-2011

2006-01-01

rets. rmt.: Carrying Linda´s stones: an anthology of Estonian women´s life stories/ editors Suzanne Stiver Lie ...[ et al.]; foreword by H. E. Aldona Wos. Tallinn: Tallinn University Press, 2006. 600 lk. : ill, kaart

Dragotsennaja osen / Tatjana Barmakova

Index Scriptorium Estoniae

Barmakova, Tatjana

2004-01-01

Moefirmade Dior, Yves Saint Laurent (jumestuskunstnik Linda Cantello), Guerlain (kunstnik Olivier Echaudemaison), Shiseido (kunstnik Tom Pecheux) meigikollektsioonidest. Diori, Kenzo ja Thierry Mugleri uutest parfüümidest. "Kenzoairi" parfüümipudeli disainis klaasikunstnik Laura de Santillana

Public Participation: What has the Constitutional Court given the ...

African Journals Online (AJOL)

Public Participation: What has the Constitutional Court given the public? ... Linda Nyati explores the duty to facilitate public participation in legislative processes in terms of ... This issue, the article demonstrates, is highly pertinent to citizens in ...

Live yeast culture and monensin in high grain diets for cattle: rumen fermentation and “in situ” degradability Leveduras vivas e monensina em dietas de alto concentrado para bovinos: parâmetros ruminais e degradabilidade "in situ"

Directory of Open Access Journals (Sweden)

José Carlos Machado Nogueira Filho

2010-03-01

fermentação, os protozoários e a degradação ruminal in situ. Quatro novilhos Nelore canulados no rúmen foram alimentados com uma dieta base (2,8Mcal EM/kg de matéria seca [MS]; 14% PB e submetidos, de acordo com um delineamento Quadrado Latino 4x4, aos tratamentos: controle (CON; sem aditivos, levedura (LEV; 0,6 g/kg de MS, monensina (MON; 0,3g/kg de MS e monensina mais levedura (MON+LEV. Avaliou-se os números de protozoários e os parâmetros de fermentação ruminal e de degradação do milho (MI, farelo de soja (FS e casca de soja (CS. Não houve feito sobre o pH, butirato e N amoniacal, mas todos tratamentos diminuíram a concentração total de ácidos graxos de cadeia curta. MON e MON+LEV reduziram acetato (% e a relação acetato:propionato. O propionato aumentou com MON e MON+LEV e com LEV nos tempos 4 e 6 horas após a alimentação. LEV aumentou o número de protozoários enquanto que MON e MON+LEV os inibiram. Não houve efeitos de LEV e MON+LEV sobre a degradação in situ de nenhum dos alimentos avaliados, porém a monensina aumentou a taxa de degradação do FDN da CS. Os efeitos da monensina sobre a fermentação ruminal são mais significantes do que aqueles observados com leveduras, e a combinação de ambos os aditivos não potencializa os resultados.

Leonardo da Vinci on alati moes / Linda Järve

Index Scriptorium Estoniae

Järve, Linda, 1946-

2004-01-01

Tallinna Energiakeskuses avati Leonardo da Vinci lennumasin, mille aluseks on Milanos Biblioteca Ambrosiana raamatukogus säilitatavad joonised. Artikli autor külastas Itaalias Leonardo da Vinciga seotud paiku

Portfoolio õpetajakoolituses / Willy Meeus, Linda Van Looy, Mart Laanpere

Index Scriptorium Estoniae

Meeus, Willy

2004-01-01

Õpimapi ajaloost, karakteristikutest ja kasutamise võimalustest konstruktivistliku õpikeskkonna osana. Portfoolio rakendamisest Brüsseli Vaba Ülikooli ja Tallinna Pedagoogikaülikooli õpetajakoolituses

Linda Maria Koldau: Die Moldau. Smetanas Zyklus "Mein Vaterland"

Czech Academy of Sciences Publication Activity Database

Gabrielová, Jarmila

2009-01-01

Roč. 46, 1-2 (2009), s. 190-191 ISSN 0018-7003 Institutional research plan: CEZ:AV0Z90580513 Keywords : Bedřich Smetana * "My Fatherland" ("My Country") Cycle Subject RIV: AL - Art, Architecture, Cultural Heritage

Riiklikud autasud haridustöötajaile / Linda Järve

Index Scriptorium Estoniae

Järve, Linda, 1946-

2003-01-01

President Arnold Rüütel omistas seoses Eesti Vabariigi 85. aastapäevaga riiklikke autasusid teiste hulgas ka silmapaistvatele haridusinimestele. Riigivapi III klassi pälvis P. Kreitzberg. Valgetähe V klassi saab Tallinna Lilleküla Gümnaasiumi õpetaja L. Metsaorg, Valgetähe IV klassi ordeni saab K. Võlli, TPÜ emeriitprofessor andragoog T. Märja saab IV klassi Valgetähe ordeni

Injection septum magnets for the Loma Linda medical accelerator

International Nuclear Information System (INIS)

Satti, J.A.

1987-01-01

The injection beamline runs over the last magnet before a long straight section and is then displaced downward 55.88 cm to the accelerator beamline. The displacement is magnetic and the final deflection onto the synchrotron orbit is by an electric kicker. The first component, the reverse septum magnet, bends the injection beam 25/degree/ downward. This is followed by the injection septum (20/degree/ bend upward) and the final injection kicker (5/degree/ bend upward). The septum magnets produce a peak field of 3.4 K gauss at a current of 28,000 amperes within a 0.1 msec long pulse. The electric kicker produces a field of 7.3 KV/cm with a pulse length of 0.0011 msec. The septum magnets are similar to each other in construction with a bending radium of 72.7 cm. The curvature is required to increase the effective aperture. Each magnet has a single-turn copper coil bonded to a stainless steel plate for reinforcement. This eliminates insulating material, which could be subject to radiation damage, at the septum. The stainless steel plate is welded to the magnet laminations. The current is confined to the septum by the insulation between the laminations, which are a standard core material. The total septum thickness with shield is 1.227 cm. Pulsing the magnet eliminates the need for water cooling. 2 refs., 4 figs

"800 aastat" - millest ja milleks? / Linda Kaljundi, Marek Tamm

Index Scriptorium Estoniae

Kaljundi, Linda, 1979-

2008-01-01

Tallinna Ülikooli keskaja keskuse ja Põhjamaade keskajauuringute keskuse koostöös Tallinnas 22.-24. maini korraldatavast konverentsist "The Chronicle of Henry of Livonia : Crusading and Chronicle Writing at the Medieval Baltic Frontier"

Development of air fuel ratio sensor; A/F sensor no kaihatsu

Energy Technology Data Exchange (ETDEWEB)

Sakawa, T; Hori, M [Denso Corp., Aichi (Japan); Nakamura, Y [Toyota Motor Corp., Aichi (Japan)

1997-10-01

The Air Fuel Ratio Sensor (A/F sensor), which is applied to a 1997 model year Low Emission Vehicle (LEV) was developed. This sensor enables the detection of the exhaust gas air fuel ratio, both lean and rich of stoichiometric. It has an effective air fuel ratio range from 12 to 18 as required for LEV regulation. It has the fast light off, - within 20 seconds - to minimize exhaust hydrocarbon content. Further, it has fast response time, less than 200 msec, to improve the air fuel ratio controllability. 3 refs., 7 figs.

La n?phrotoxicite secondaire ? l'hyperbilribinemie: ? propos d'un cas

OpenAIRE

Jomni, Med Taieb; Largueche, Mouna; Kaab, Badreddine Ben; Abdelaal, Imen; Bellakhal, Syrine; Douggui, Med H?di

2015-01-01

L'hyperbilirubin?mie ? des taux ?lev?s est nephrotoxique par divers m?canismes allant de la tubulopathie proximale aux d?p?ts massifs de bilirubine. Cette entit? bien que d?crite depuis le d?but du vingti?me si?cle est souvent m?connue dans la litt?rature moderne. Nous rapportons le cas d'un patient pr?sentant une cirrhose probablement d'origine m?dicamenteuse (Amiodarone*), dont la fonction r?nale s'est alt?r?e parall?lement ? la majoration de l'hyperbilirubin?mie. Aucune autre cause de l'in...

Effects of in vitro exposure to ivermectin and levamisole on the expression patterns of ABC transporters in Haemonchus contortus larvae

Directory of Open Access Journals (Sweden)

Ali Raza

2016-08-01

Full Text Available This study investigated the interaction of ATP binding cassette (ABC transport proteins with ivermectin (IVM and levamisole (LEV in larvae of susceptible and resistant isolates of Haemonchus contortus in vitro by measuring transcription patterns following exposure to these anthelmintics. Furthermore, we studied the consequences of drug exposure by measuring the sensitivity of L3 to subsequent exposure to higher drug concentrations using larval migration assays. The most highly transcribed transporter genes in both susceptible and resistant L3 were pgp-9.3, abcf-1, mrp-5, abcf-2, pgp-3, and pgp-10. The resistant isolate showed significantly higher transcription of pgp-1, pgp-9.1 and pgp-9.2 compared to the susceptible isolate. Five P-gp genes and the haf-6 gene showed significantly higher transcription (up to 12.6-fold after 3 h exposure to IVM in the resistant isolate. Similarly, five P-gp genes, haf-6 and abcf-1 were transcribed at significantly higher levels (up to 10.3-fold following 3 h exposure to LEV in this isolate. On the other hand, there were no significant changes in transcriptional patterns of all transporter genes in the susceptible isolate following 3 and 6 h exposure to IVM or LEV. In contrast to these isolate-specific transcription changes, both isolates showed an increase in R-123 efflux following exposure to the drugs, suggesting that the drugs stimulated activity of existing transporter proteins in both isolates. Exposure of resistant larvae to IVM or LEV resulted, in some instances, in an increase in the proportion of the population able to migrate at the highest IVM concentrations in subsequent migration assays. The significant increase in transcription of some ABC transporter genes following 3 h exposure to both IVM and LEV in the resistant isolate only, suggests that an ability to rapidly upregulate protective pathways in response to drugs may be a component of the resistance displayed by this isolate.

Hemolytic performance of a MagLev disposable rotary blood pump (MedTech Dispo): effects of MagLev gap clearance and surface roughness.

Science.gov (United States)

Hoshi, Hideo; Asama, Junichi; Hijikata, Wataru; Hara, Chikara; Shinshi, Tadahiko; Yasuda, Toshitaka; Ohuchi, Katsuhiro; Shimokohbe, Akira; Takatani, Setsuo

2006-12-01

Mechanical shaft seal bearing incorporated in the centrifugal blood pumps contributes to hemolysis and thrombus formation. In addition, the problem of durability and corrosion of mechanical shaft seal bearing has been recently reported from the safety point of view. To amend the shortcomings of the blood-immersed mechanical bearings, a magnetic levitated centrifugal rotary blood pump (MedTech Dispo Model 1; Tokyo Medical and Dental University, Tokyo, Japan) has been developed for extracorporeal disposable application. In this study, the hemolytic performance of the MedTech Dispo Model 1 centrifugal blood pump system was evaluated, with special focus on the narrow blood path clearance at the magnetic bearing between rotor and stator, and on the pump housing surface roughness. A pump flow of 5 L/min against the head pressure of 100 mm Hg for 4 h was included in the hemolytic test conditions. Anticoagulated fresh porcine blood was used as a working fluid. The clearance of blood path at the magnetic bearing was in the range of 100-250 micro m. Pump housing surface roughness was controlled to be around Ra = 0.1-1.5 micro m. The lowest hemolytic results were obtained at the clearance of 250 micro m and with the polished surface (Ra = 0.1 micro m) yielding the normalized index of hemolysis (NIH) of less than 0.001 g/100 L, which was 1/5 of the Biopump BP-80 (Medtronic Inc., Minneapolis, MN, USA, and 1/4 of the BPX-80. In spite of rough surface and narrow blood path, NIH levels were less than clinically acceptable level of 0.005 g/100 L. The noncontact, levitated impeller system is useful to improve pump performance in blood environment.

75 FR 25885 - The Merit Systems Protection Board (MSPB) is Providing Notice of the Opportunity to File Amicus...

Science.gov (United States)

2010-05-10

... MERIT SYSTEMS PROTECTION BOARD The Merit Systems Protection Board (MSPB) is Providing Notice of the Opportunity to File Amicus Briefs in the Matter of Larry L. Evans v. Department of Veterans Affairs, MSPB Docket Number AT-3330-09-0953- I-1. AGENCY: Merit Systems Protection Board. ACTION: Notice...

Insights for the Third Offset: Addressing Challenges of Autonomy and Artificial Intelligence in Military Operations

Science.gov (United States)

2017-09-01

54 Larry Lewis, Operation Iraqi Freedom: Ground-to-Air Fratricide (U). CNA Research Memorandum CRM D0008910.A4, July 2004, //Secret. (Portion cited...Operation Iraqi Freedom: Ground-to-Air Fratricide (U). CNA Research Memorandum CRM D0008910.A4. Secret. (Portions cited in the present report are

Vilgub, välgub ja kihutab / Alar Niineväli

Index Scriptorium Estoniae

Niineväli, Alar

2008-01-01

Seiklusfilm "Speed Racer" : stsenaristid-režissöörid Andy ja Larry Wachowski : Ameerika Ühendriigid 2008. Teose aluseks on tatsuo Yoshida manga põhjal loodud 52-osaline animaseriaal "Mahha GoGoGo" (1967-1968). Lisatud: M.L. "Lihtsalt Wachowsid?" režissööride eraelust

Shuaib Lwasa Makerere University

International Development Research Centre (IDRC) Digital Library (Canada)

Shuaib Lwasa

2012-12-02

Dec 2, 2012 ... Examples; Sine Saloum mangroove restoration, coastal erosion control in Bangladesh (Pieter de Hoochweg, 2010, Larry Luxner. 2012). ▫. Influenced by anticipated and experienced hazards; sea level rise, storm surges, flooding e.t.c. ▫. The Policy context. ▫. Key Issues of Policy: Goals -> Rules / guidelines ...

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (82nd, New Orleans, Louisiana, August 3-8, 1999). Magazine and Visual Communication Divisions.

Science.gov (United States)

Association for Education in Journalism and Mass Communication.

The Magazine and Visual Communication Divisions section of the Proceedings contains the following 8 papers: "Beefcake, Breadwinner, or Babysitter: A Content Analysis of Male Images in Female-Targeted Magazine Advertising, 1978-1998" (Mikalee Dahle and Jennifer Greer); "The Impact of Larry Flynt: An Overview of One Publisher's Legal…

Joint Distraction Treatments of Intra-Articular Fracture-Induced Posttraumatic Osteoarthritis in a Large Animal Model

Science.gov (United States)

2017-10-01

both in military combat and training conditions and in active civilian populations . The purpose of this expansion project is to use the novel...training experience including an NIH T32 and several K-award mentorships; and clinical co-mentor, Dr. Larry Marsh, a world class trauma surgeon and

American Academy of Home Care Medicine

Science.gov (United States)

... articles Community Paramedicine Is at the Forefront of Home Care Medicine By Linda DeCherrie, MD Learn how community ... You can still learn from the leaders in home-based primary care. All of the stand-out sessions will be ...

Go4Life

Medline Plus

Full Text Available ... strength! Stronger muscles can make it easier to do everyday things like get up from a chair, ... 797 views Trainer Sandy shows Linda how to do lower body exercises in her office with Go4Life's ...

New Tobacco Trends (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

Cigarette smoking in the United States has been on a steady decline over the past 50 years. However, new tobacco products are becoming increasingly popular. In this podcast, Dr. Linda Neff discusses the dangerous new trends in tobacco use.

Go4Life

Medline Plus

Full Text Available ... 17,679 views Exercise your upper body at work like Linda with Go4Life's Wall Pushups. CC 1: ... 19 Play next Play now Choosing Nutrient Dense Foods - Duration: 6 minutes, 19 seconds. National Institute On ...

Näitus ühendab erineva vaimumaailmaga inimesi / Helgi Kaldma

Index Scriptorium Estoniae

Kaldma, Helgi, 1933-2011

2007-01-01

Rahvusvaheline autsaiderkunstnike näitus "Kunst ühendab" Viljandis Kondase keskuses. Esindatud on päevakeskused Singel ja Vinger, Viljandi Keldristuudio, Tallinna internaatkool, Võisiku hooldekodu, Peterburi psühhiaatriahaigla kunstistuudio ja Moskva organisatsioon Uued Võimalused. Korraldas Viljandimaa Singel juhataja Linda Luhse

Iskusstvo iz-za bolnitshnoi stenõ / Svetlana Karabut

Index Scriptorium Estoniae

Karabut, Svetlana

2008-01-01

Autsaiderite kunsti näitus "Kunst ühendab" Viljandis Ugala teatri fuajees. Näidatakse eesti taastuskeskuste Singel ja Vinger ning Peterburi psühhiaatriahaigla kunstistuudio töid. Kommenteerib Linda Luhse. Intervjuu Peterburi haigla kunstistuudio juhendajate Tatjana ja Vladimir Barsukovidega

Lugemisaasta tõstis raamatukogude mainet / Reet Olevsoo

Index Scriptorium Estoniae

Olevsoo, Reet, 1956-

2011-01-01

28. veebruaril 2011 toimunud ERÜ aastakoosolekul tehti kokkuvõtteid 2010. a tegevusest ning anti üle aasta- ja teenetepreemiad. Aastapreemia 2010 pälvis Külli Solo ning teenetepreemia anti Ivi Tingrele, ERÜ auliikmeteks valiti Elle Tarik ja Linda Kask

Batch and fixed bed adsorption of levofloxacin on granular activated carbon from date (Phoenix dactylifera L.) stones by KOH chemical activation.

Science.gov (United States)

Darweesh, Teeba M; Ahmed, Muthanna J

2017-03-01

Granular activated carbon (KAC) was prepared from abundant Phoenix dactylifera L. stones by microwave- assisted KOH activation. The characteristics of KAC were tested by pore analyses, scanning electron microscopy (SEM) and Fourier transforms infrared spectroscopy (FTIR). The adsorption behavior of levofloxacin (LEV) antibiotic on KAC with surface area of 817m 2 /g and pore volume of 0.638cm 3 /g were analyzed using batch and fixed bed systems. The equilibrium data collected by batch experiments were well fitted with Langmuir compared to Freundlich and Temkin isotherms. The effect of flow rate (0.5-1.5ml/min), bed height (15-25cm), and initial LEV concentration (75-225mg/l) on the behavior of breakthrough curves was explained. The fixed bed analysis showed the better correlation of breakthrough data by both Thomas and Yoon-Nelson models. High LEV adsorption capacity of 100.3mg/g was reported on KAC, thus being an efficient adsorbent for antibiotic pollutants to protect ecological systems. Copyright © 2017 Elsevier B.V. All rights reserved.

Unsteady lift and thrust of a 2D flapping thin airfoil in the presence of additional leading edge vortices

Science.gov (United States)

Alaminos-Quesada, Javier; Fernandez-Feria, Ramon

2017-11-01

The effect of leading-edge vortices (LEVs) on the lift, thrust and moment of a two-dimensional heaving and pitching foil is analyzed from the unsteady, linear potential theory. General expressions taking into account the effect of unsteady point vortices interacting with the oscillatory trailing wake are first derived. Then, simplified expressions for the initial stages of the growing LEV on each half-stroke are used to obtain analytical closed expressions for the main contribution of these vortices to the lift, thrust and moment. It is found that, within the linear potential framework and the Brown-Michael model, the LEV contributes to the aerodynamic forces and moment only for combined pitching and heaving motions of the foil, being a relevant contribution for sufficiently large values of the product of the reduced frequency and the amplitude of the heaving and/or pitching motions. The results are compared with available experimental data and numerical simulations. Supported by the Ministerio de Economia y Competitividad of Spain Grants No. DPI2013-40479-P and DPI2016-76151-C2-1-R.

Paramagnetic ionic liquids for measurements of density using magnetic levitation.

Science.gov (United States)

Bwambok, David K; Thuo, Martin M; Atkinson, Manza B J; Mirica, Katherine A; Shapiro, Nathan D; Whitesides, George M

2013-09-03

Paramagnetic ionic liquids (PILs) provide new capabilities to measurements of density using magnetic levitation (MagLev). In a typical measurement, a diamagnetic object of unknown density is placed in a container containing a PIL. The container is placed between two magnets (typically NdFeB, oriented with like poles facing). The density of the diamagnetic object can be determined by measuring its position in the magnetic field along the vertical axis (levitation height, h), either as an absolute value or relative to internal standards of known density. For density measurements by MagLev, PILs have three advantages over solutions of paramagnetic salts in aqueous or organic solutions: (i) negligible vapor pressures; (ii) low melting points; (iii) high thermal stabilities. In addition, the densities, magnetic susceptibilities, glass transition temperatures, thermal decomposition temperatures, viscosities, and hydrophobicities of PILs can be tuned over broad ranges by choosing the cation-anion pair. The low melting points and high thermal stabilities of PILs provide large liquidus windows for density measurements. This paper demonstrates applications and advantages of PILs in density-based analyses using MagLev.

Antibacterial and synergy of berberines with antibacterial agents against clinical multi-drug resistant isolates of methicillin-resistant Staphylococcus aureus (MRSA).

Science.gov (United States)

Zuo, Guo-Ying; Li, Yang; Han, Jun; Wang, Gen-Chun; Zhang, Yun-Ling; Bian, Zhong-Qi

2012-08-29

Antibacterial activity of berberine (Ber) and 8-acetonyl-dihydroberberine (A-Ber) alone and combined uses with antibacterial agents ampicillin (AMP), azithromycin (AZM), cefazolin (CFZ) and levofloxacin (LEV) was studied on 10 clinical isolates of SCCmec III type methicillin-resistant Staphylococcus aureus (MRSA). Susceptibility to each agent alone was tested using a broth microdilution method and the chequerboard and time-kill tests for the combined evaluations, respectively. The alone MICs/MBCs (μg/mL) ranges were 32-128/64-256 (Ber) and 32-128/128-512 (A-Ber). Significant synergies were observed for the Ber (A-Ber)/AZM and Ber (A-Ber)/LEV combinations against 90% of the tested MRSA strains, with fractional inhibitory concentration indices (FICIs) values ranged from 0.188 to 0.500. An additivity result was also observed for the Ber/AZM combination by time-kill curves. These results demonstrated for the first time that Ber and A-Ber enhanced the in vitro inhibitory efficacy of AZM and LEV to a same extent, which had potential for further investigation in combinatory therapeutic applications of patients infected with MRSA.

Engineering control technologies to reduce occupational silica exposures in masonry cutting and tuckpointing.

Science.gov (United States)

Meeker, John D; Cooper, Michael R; Lefkowitz, Daniel; Susi, Pam

2009-01-01

A number of tasks in construction generate worker overexposures to respirable crystalline silica dust, which is a significant contributor to occupational mortality and morbidity. This study evaluated the performance of commercially available engineering controls used in dusty construction tasks commonly performed by bricklayers. Local exhaust ventilation (LEV) controls for a portable abrasive cutter and for tuckpointing grinders were examined at a bricklayers' training center, as were two stationary wet saws. Personal breathing zone air samples were collected with and without the use of LEV or water suppression during simulated concrete block cutting, brick cutting, and tuckpointing. Compared with the use of no exposure control during block and brick cutting, the portable LEV unit significantly reduced mean respirable quartz exposures by 96% for block cutting and 91% for brick cutting (p controls (p control and no-control scenarios. These reductions with commercially available off-the-shelf tools demonstrate the effectiveness of engineering control interventions to reduce crystalline silica exposures in construction. Strategies to further improve control performance and approaches for increasing control interventions in construction are needed.

Harry Potter ja Scarlett käivad kohut / Ilona Martson

Index Scriptorium Estoniae

Martson, Ilona, 1970-

2001-01-01

Alice Randalli romaan "Tuul on läinud" - samad sündmused kui Margaret Mitchelli romaanis "Tuulest viidud", ainult neegerorjade vaatevinklist. Nancy Stofferi raamatud "Larry Potter ja tema parim sõber Lilly" ja "Legend Rah'ist ja Mugudest" ilmusid 1984. a. Joanne Kathleen Rowlingi "Harry Potter" lood aga valmisid hiljem

Massive public investment needed to grow green economy.

Science.gov (United States)

2009-01-01

The President of the Communications Workers of America, Larry Cohen, urges large-scale investments in research and technology in response to economic turmoil and climate change. He envisions one million made-in-America hybrid cars running on U.S. roadways by 2015 and use of alternative energy doubling within three years.

Interpretation Analysis as a Competitive Event.

Science.gov (United States)

Nading, Robert M.

Interpretation analysis is a new and interesting event on the forensics horizon which appears to be attracting an ever larger number of supporters. This event, developed by Larry Lambert of Ball State University in 1989, requires a student to perform all three disciplines of forensic competition (interpretation, public speaking, and limited…

Increased Awareness, Increased Appreciation

Science.gov (United States)

Nightingale, Barbra

2015-01-01

This article provides a student's viewpoint in response to Larry Andrews' article, "The Humanities Are Dead! Long Live the Humanities!," which addresses and solidifies the notion that, at least from the standpoint of academicians, the humanities are alive and well. The author believes that a broader base of learning, an increased…

Evaluating the Relationship Between Neuropsychological Function and Cognitive Performance

Science.gov (United States)

2012-08-01

Larry.Moore.ctr2@wpafb.af.mil) L3 Communications 5950 East Sossaman Road, Suite 102, Mesa, AZ 85212 USA Abstract The last 2 decades have...Viard, A., Schürhoff, F., Recasens, C., Martinot, M. L. P., Leboyer, M., & Martinot, J-L. (2003). Conscious and subliminal conflicts in normal

Experimental Design and Analysis for the FIST (Fire Support Team) Force Development Testing and Experimentation II.

Science.gov (United States)

1985-10-01

median service time for a FIST IHQ to service Copperhead missions while in review mode and for mission workload (FO + ARMOR + CPH) was only 6.0...07703 Uazhin.tou, DC 20036 2 Coui-,ander 1 Comwanaer US Aruy larry Diaiaond Labs. US Army Belvoir ATTN: AIILHD- TD , Dr. Scully Research & Development

Saving Our Seniors: Preventing Elder Abuse, Neglect, and Exploitation. Hearing before the Special Committee on Aging, United States Senate, One Hundred Seventh Congress, First Session.

Science.gov (United States)

Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

In this report of a congressional hearing, testimony includes statements and prepared statements of these four senators: John Breaux, Larry Craig, Debbie Stabenow, and Herbert Kohl. Panel I is presented by the Acting Assistant Attorney General, United States (U.S.) Department of Justice. Panel II consists of individuals representing the National…

Student Engagement: Key to Personalized Learning

Science.gov (United States)

Ferlazzo, Larry

2017-01-01

Personalized learning has the potential to greatly improve student achievement--but realistic teachers know that any instructional strategy will only be effective if students are willing to do the work. That is why Larry Ferlazzo emphasizes the importance of weaving intrinsic motivation into every personalized learning classroom. Four key elements…

Wat komt bovenaan de lijst bij Google?

NARCIS (Netherlands)

Litvak, Nelly

2006-01-01

In 1998 presenteerden de PhD-studenten Sergey Brin en Larry Page uit Stanford het artikel ‘The anatomy of a Large-Scale Hypertextual Web Search Engine’ op het zevende World-Wide-Web-congres in Brisbane, Australië. Zij beschreven de Web-zoekmachine Google, waarvan de blanco bladzijde tegenwoordig zo

Alzheimer's Disease and Related Dementias. Hearing before the Subcommittee on Aging of the Committee on Labor and Human Resources. United States Senate, Ninety-Ninth Congress, Second Session on Review of Health Care Services Available for People with Alzheimer's Disease and Related Dementia and To Review Proposals Related to the Treatment of Alzheimer's Disease.

Science.gov (United States)

Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

A Senate hearing reviewing health care services available for people with Alzheimer's disease and related dementia and reviewing proposals related to the treatment of Alzheimer's disease is presented in this document. Statements are given by Senators Charles E. Grassley, Albert Gore, Paula Hawkins, Howard M. Metzenbaum, Larry Pressler, and Paul…

Thinking Fast and Slow about Causality: Response to Palinkas

Science.gov (United States)

Marsh, Jeanne C.

2014-01-01

Larry Palinkas advances the developing science of social work by providing an explanation of how social science research methods, both qualitative and quantitative, can improve our capacity to draw casual inferences. Understanding causal relations and making causal inferences--with the promise of being able to predict and control outcomes--is…

Analysis of Servant-Leadership Characteristics: Case Study of a For-Profit Career School President

Science.gov (United States)

Hiatt, Elaine M.

2010-01-01

Servant leadership is a challenging leadership philosophy to study empirically. The purpose of this qualitative descriptive case study was to determine if an effective leader of a for-profit career school displays the 10 servant-leader characteristics, identified by Larry R. Spears (1995) in "Reflections on Leadership," according to respondents,…

An Evolutionary Approach to the Biological Management of Invasive Brown Treesnakes (Boiga irregularis) on Guam

Science.gov (United States)

2012-03-14

only two snake species on the Guam, the other of which is a burrowing blind snake Ramphotyphlops braminus (possibly introduced as well), and none of...descriptions of three new species. Systematic Parasitology 1:127-140. Roberts, L. S. and J. J. Janovy. 2005. Gerald D. Schmidt and Larry S. Roberts

Structure, Function and Diversity of the Healthy Human Microbiome

Science.gov (United States)

2012-06-14

Durbin, R. Fast and accurate long-read alignment with Burrows –Wheeler transform. Bioinformatics 26, 589–595 (2010). 26. Giannoukos, G. et al...Feldgarden2, Victor M. Felix7, Sheila Fisher2, Anthony A. Fodor41, Larry J. Forney42, Leslie Foster6, Valentina Di Francesco19, Jonathan Friedman43

Resource-Efficient Data-Intensive System Designs for High Performance and Capacity

Science.gov (United States)

2015-09-01

76, 79, 80, and 81.] [9] Anirudh Badam, KyoungSoo Park, Vivek S. Pai, and Larry L. Peterson. HashCache: cache storage for the next billion. In Proc...Jeffrey Dean, Sanjay Ghemawat, Wilson C. Hsieh, Deborah A. Wallach, Mike Burrows , Tushar Chandra, Andrew Fikes, and Robert E. Gruber. Bigtable: A

Tide Gauge and Satellite Altimetry Integration for Storm Surge Prediction

DEFF Research Database (Denmark)

Andersen, Ole Baltazar; Cheng, Yongcun; Deng, X.

2013-01-01

of the Northeast Australia, we have investigated several large cyclones causing much destruction when they hit the coast. One of these being the Cyclone Larry, which hit the Queensland coast in March 2006 and caused both losses of lives as well as huge devastation. Here we demonstrate the importance of integrating...

77 FR 26777 - Endangered Species; Marine Mammals; Issuance of Permits

Science.gov (United States)

2012-05-07

... not operate to the disadvantage of the endangered species, and (3) The granted permit would be..., 2012. 64654A Double Springs 77 FR 6816; March 14, 2012. Partnership Ltd. February 9, 2012. 64656A Double Springs 77 FR 6816; March 14, 2012. Partnership Ltd. February 9, 2012. 64723A Larry Friesenhahn...

Making History: SACES Presidential Leadership 1949-1998.

Science.gov (United States)

Sheeley, Vernon Lee

This booklet provides educational, professional, and biographical information on 48 presidents of the Southern Association for Counselor Education and Supervision. A photo of each president is included. All leaders from 1949-1998 are covered. The presidents are: Donna Henderson, Debra Cobia, Pamela Paisley, Larry C. Loesch, Charlotte M. Taylor,…

Study of the protective effects of nootropic agents against neuronal damage induced by amyloid-beta (fragment 25-35) in cultured hippocampal neurons.

Science.gov (United States)

Sendrowski, Krzysztof; Sobaniec, Wojciech; Stasiak-Barmuta, Anna; Sobaniec, Piotr; Popko, Janusz

2015-04-01

Alzheimer's disease (AD) is a common neurodegenerative disorder, in which progressive neuron loss, mainly in the hippocampus, is observed. The critical events in the pathogenesis of AD are associated with accumulation of β-amyloid (Aβ) peptides in the brain. Deposits of Aβ initiate a neurotoxic "cascade" leading to apoptotic death of neurons. Aim of this study was to assess a putative neuroprotective effects of two nootropic drugs: piracetam (PIR) and levetiracetam (LEV) on Aβ-injured hippocampal neurons in culture. Primary cultures of rat's hippocampal neurons at 7 day in vitro were exposed to Aβ(25-35) in the presence or absence of nootropics in varied concentrations. Flow cytometry with Annexin V/PI staining was used for counting and establishing neurons as viable, necrotic or apoptotic. Additionally, release of lactate dehydrogenase (LDH) to the culture medium, as a marker of cell death, was evaluated. Aβ(25-35) caused concentration-dependent death of about one third number of hippocampal neurons, mainly through an apoptotic pathway. In drugs-containing cultures, number of neurons injured with 20 μM Aβ(25-35) was about one-third lesser for PIR and almost two-fold lesser for LEV. When 40 μM Aβ(25-35) was used, only LEV exerted beneficial neuroprotective action, while PIR was ineffective. Our results suggest the protective potential of both studied nootropics against Aβ-induced death of cultured hippocampal neurons with more powerful neuroprotective effects of LEV. Copyright © 2014 Institute of Pharmacology, Polish Academy of Sciences. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

75 FR 29774 - Office of Child Support Enforcement; Privacy Act of 1974; Computer Matching Agreement

Science.gov (United States)

2010-05-27

... of Federal Systems, Office of Automation and Program Operations, Office of Child Support Enforcement... INFORMATION CONTACT: Linda Deimeke, Director, Division of Federal Systems, Office of Automation and Program..., home addresses, and employment information. E. Inclusive Dates of the Matching Program The computer...

The role of C-type lectin receptors in human skin immunity: immunological interactions between dendritic cells, Langerhans cells and keratinocytes

NARCIS (Netherlands)

van den Berg, L.M.

2013-01-01

Langerhanscellen kunnen actief contact met elkaar maken in de huid waardoor ze informatie over binnendringende ziekteverwekkers uitwisselen. Dit leidt tot een efficiënte afweerreactie. Linda van den Berg geeft hier een beschrijving van. Daarnaast ontdekte ze dat een koolhydraat afkomstig van een

"Making Better Colleges": AAC's Century of Change and Commitment

Science.gov (United States)

Eisenmann, Linda

2015-01-01

In this article, Linda Eisenman reviews the history of the "Association of American Colleges" (AAC), whose 150 college executives gathered in Chicago in 1915 to create the Association, and chose "inclusiveness" and "interhelpfulness" as twin themes to animate their organization. "Inclusiveness" allowed many…

South African Journal of Education: Editorial Policies

African Journals Online (AJOL)

Linda Liebenberg, Dalhousie University, Canada. Joanna Madalińska-Michalak, University of Warsaw, Poland. Aleidine Moeller, University of Nebraska–Lincoln, USA. Karen Murphy, The Pennsylvania State University, USA. Salim Razı, Çanakkale Onsekiz Mart University, Turkey. Rose Ruto-Korir, Moi University, Kenya.

Go4Life

Medline Plus

Full Text Available ... some of these Go4Life exercises to improve your flexibility! 2:48 Play next Play now Go4Life Exercise-- ... 17,679 views Exercise your upper body at work like Linda with Go4Life's Wall Pushups. CC 1: ...

Pakendidisain : ühekordne alumiiniumlusikas / Triin Ojari

Index Scriptorium Estoniae

Ojari, Triin, 1974-

2005-01-01

Eesti Kunstiakadeemia tootedisaini osakonna IV kursuse üliõpilane Riho Tiivel võitis Itaalias toimunud disainikonkursi ReAL 13 (Recycling Aluminium) "Eating Anywhere" peapreemia oma alumiiniumist lusikaga "Spoon Container". II - Giulio Iacchetti, III - Miki Astori, Linda Bigatti, ergutuspreemia - Sam Sannia. 4 ill

Supermodellid läbi aegade / Kaarin Kivirähk

Index Scriptorium Estoniae

Kivirähk, Kaarin

2014-01-01

20. sajandi supermodellid: Anita Colby, Lisa Fonssagrives, Dorian Leigh, Suzy Parker, Dovima, Jean Shrimpton, Twiggy, Jerry Hall, Iman, Lauren Hutton, Marisa Berenson, Janice Dickinson, Cindy Crafword, Paulina Porizkova, Gia Carangi, Elle Macpherson, Linda Evangelista, Naomi Campbell, Gisele Bündchen, Kate Moss, Carmen Kass

Go4Life

Medline Plus

Full Text Available ... YouTube Red Get YouTube TV Best of YouTube Music Sports Gaming Movies TV Shows News Live Spotlight ... 17,362 views Exercise your upper body at work like Linda with Go4Life's Wall Pushups. CC 1: ...

An intercultural approach to implementing multilingualism at Rhodes ...

African Journals Online (AJOL)

2005-10-06

Oct 6, 2005 ... Russell H. Kaschula, Pamela Maseko, Lorenzo Dalvit, Thandeka Mapi, Linda Nelani,. Bulelwa Nosilela and .... fashion, trends, pop music) and of verbal and nonverbal symbols. ..... Assisted Language Learning - CALL) and specifically encourages independent learning. The ... Production of and access to.

Kullavihm ja tähesadu. Muljeid 2006. aasta "Kuldse maski" festivalilt Moskvas / Sven Karja

Index Scriptorium Estoniae

Karja, Sven, 1968-

2006-01-01

A. Tshehhovi "Onu Vanjal" põhinev "Stseenid maaelust" (Moskva teater "Okolo doma Stanislavskogo), "Polyphemose surm" (Moskva (pere)nukuteater Ten), N. Gogoli "Sinel" (lavastaja Valeri. Fokin, Sovremennik), "Koera ja hundi vahel" (lavastaja Andrei Mogutshi, Formaalne teater koostöös Nizza Rahvusteatriga), L. Andrejevi jutustuse põhjal "Jutt seitsmest ülespoodust" (lavastaja Mindaugas Karbauskis, Tabakovi teatri noortetrupp "Russian Case"), V. Nikiforova "Varjatud väljaminekud" (lavastaja Eduard Bojakov, Praktika), A. Tshehhov "Kirsiaed" ja A. Strindberg "Preili Julie" (mõlema lavastaja Jevgeni Martshell), W. Shakespeare "Kuningas Lear" (lavastaja Lev Dodin), M. Gorki "Põhjas" (lavastaja Lev Ehrenburg, Peterburi Väikene Draamateater)

Environmental assessment of lightweight electric vehicles

CERN Document Server

Egede, Patricia

2017-01-01

This monograph adresses the challenge of the environmental assessment of leightweight electric vehicles. It poses the question whether the use of lightweight materials in electric vehicles can reduce the vehicles’ environmental impact and compares the environmental performance of a lightweight electric vehicle (LEV) to other types of vehicles. The topical approach focuses on methods from life cycle assessment (LCA), and the book concludes with a comprehensive concept on the environmental assessment of LEVs. The target audience primarily comprises LCA practitioners from research institutes and industry, but it may also be beneficial for graduate students specializing in the field of environmental assessment.

TinyLev: A multi-emitter single-axis acoustic levitator

Science.gov (United States)

Marzo, Asier; Barnes, Adrian; Drinkwater, Bruce W.

2017-08-01

Acoustic levitation has the potential to enable novel studies due to its ability to hold a wide variety of substances against gravity under container-less conditions. It has found application in spectroscopy, chemistry, and the study of organisms in microgravity. Current levitators are constructed using Langevin horns that need to be manufactured to high tolerance with carefully matched resonant frequencies. This resonance condition is hard to maintain as their temperature changes due to transduction heating. In addition, Langevin horns are required to operate at high voltages (>100 V) which may cause problems in challenging experimental environments. Here, we design, build, and evaluate a single-axis levitator based on multiple, low-voltage (ca. 20 V), well-matched, and commercially available ultrasonic transducers. The levitator operates at 40 kHz in air and can trap objects above 2.2 g/cm3 density and 4 mm in diameter whilst consuming 10 W of input power. Levitation of water, fused-silica spheres, small insects, and electronic components is demonstrated. The device is constructed from low-cost off-the-shelf components and is easily assembled using 3D printed sections. Complete instructions and a part list are provided on how to assemble the levitator.

Literature: Developing Critical Awareness; Some Classroom-Tested Approaches.

Science.gov (United States)

Matthews, Dorothy, Ed.

1977-01-01

This issue of the "Illinois English Bulletin" is devoted to developing critical awareness, through poetry, values, the elements of fiction, and literary study. The first section considers approaching narrative through the use of popular materials and includes two essays: "Grim Tales in the English Classroom" by Larry Danielson and "From the Comics…

78 FR 52602 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2013-08-23

... showing requirement red, green, and amber (49 CFR 391.41(b)(10)). FMCSA recognizes that some drivers do.... Thane (OH), Larry A. Tidwell (MO), Dale Torkelson (WI), Norman Vanderzyl (IA), John Vanek (MO), James D. Vorderbruggen (MN), Desmond Waldor (PA), Alicia Waters (IL), Norman R. Wilson (WA), James G. Witt (AZ), James L...

Browse Title Index

African Journals Online (AJOL)

Items 1 - 48 of 48 ... Vol 2 (2003), Electrical Properties of Antimony (Sb) Metal Contacts to Silicon (Si) Thin Films, Abstract PDF. S. S. Oluyamo. Vol 4 (2005), Fading of radio signals from spaced synchronous satellites: dependence on source coordinates, Abstract PDF. Larry LN Amaeshi. Vol 3 (2004), Finite Element Modelling ...

Finding Their Identities

Science.gov (United States)

Lum, Lydia

2009-01-01

Every time Dr. Larry Shinagawa teaches his "Introduction to Asian American Studies" course at the University of Maryland (UMD), College Park, he finds that 10 to 20 percent of his students are adoptees. Among other things, they hunger to better comprehend the social and political circumstances overseas leading to their adoption. In…

Manned Airborne Intelligence, Surveillance, and Reconnaissance: Strategic, Tactical . . . Both?

Science.gov (United States)

2012-12-01

Program, 1996), 97, http://www.dtic.mil /cgi-bin/GetTRDoc?AD=ADA442835&Location=U2&doc=GetTRDoc.pdf. 17. Quoted in William E. Burrows , By Any Means...41. Larry Tart and Robert Keefe, The Price of Vigilance: Attacks on American Surveillance Flights (New York: Ballantine Books, 2001), 196. 42. Ibid

76 FR 36053 - Endangered and Threatened Wildlife and Plants; Revised 90-Day Finding on a Petition To Reclassify...

Science.gov (United States)

2011-06-21

..., comments, or questions concerning this finding to the above address. FOR FURTHER INFORMATION CONTACT: Larry...-920, 923). The young emerge from their nursery burrow by early to mid-June and primarily forage on...; Turner 1979, p. 51; McDonald 1993, p. 9). Well-drained soils are necessary for Utah prairie dogs' burrows...

Censorship and the Media.

Science.gov (United States)

Rohrer, Daniel Morgan

This review of current legal practices with respect to censorship in the areas of obscenity and pornography contains a history of anti-obscenity legislation; a review of the efforts of the United States Supreme Court and lower courts to define obscenity; a discussion of publisher Larry Flynt's battle against the "community standards"…

Book Review: Computer Forensics: Principles and Practices

Directory of Open Access Journals (Sweden)

Jigang Liu

2007-09-01

Full Text Available Linda Volonino, Reynaldo Anzaldua, and Jana Godwin (2007. Computer Forensics: Principles and Practices. Pearson/Prentice Hall. 534 pages, ISBN: 0-13-154727-5 (paper, US$85.33Reviewed by Jigang Liu (Jigang.Liu@metrostate.edu, Department of Information and Computer Sciences, College of Arts and Sciences, Metropolitan State University, St. Paul, MN 55106“Computer Forensics: Principles and Practices” by Linda Volonino, Reynaldo Anzaldua, and Jana Godwin, published by Pearson/Prentice Hall in 2007 is one of the newest computer forensics textbooks on the market. The goal of the book, as the authors put it, is to teach “students who want to learn about electronic evidence – including what types exist and where it may be found – and the computer forensics methods to investigate it” so that they will be prepared “in a career in information security, criminal justice, accounting, law enforcement, and federal investigations – as well as computer forensics.”Linda, Reynaldo, and Jana are not only experienced college professors, but also industry bounded professionals. All of them have substantial working experience with law firms or law enforcement in dealing with both civil and criminal cases. They are all certified information system security professionals (CISSP. Their teaching experience at the college level and their working experience on real cases make this book a must-read book for a college professor.(see PDF for full review

Diferencias de dureza del agua y las tasas de longevidad en la península de nicoya y los otros distritos de Guanacaste

Directory of Open Access Journals (Sweden)

Darner A. Mora-Alvarado

2015-09-01

Verificar si el consumo de agua “dura” es un factor protector común de la longevidad de los habitantes en las restantes “Zonas Azules” del mundo, a saber Cerdeña (Italia, Okinawa (Japón, Loma Linda (California EUA e Icaria (Grecia.

Journal of Earth System Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Earth System Science; Volume 121; Issue 3. Chemical characterisation of meltwater draining from Gangotri Glacier, Garhwal Himalaya, India. Virendra Bahadur Singh A L Ramanathan Jose George Pottakkal Parmanand Sharma Anurag Linda Mohd Farooq Azam C Chatterjee. Volume 121 Issue ...

75 FR 44810 - Submission for OMB Review; Comment Request

Science.gov (United States)

2010-07-29

...: Employee Benefits Security Administration, Department of Labor. ACTION: Submission for OMB Review; Comment... ICR, with applicable supporting documentation; including, among other things, a description of the... RegInfo.gov Web site at http://www.reginfo.gov/public/do/PRAMain or by contacting Linda Watts Thomas...

Hea disaineri kätte võib usaldada nii büroo kui kodu / Tiina Salumäe

Index Scriptorium Estoniae

Salumäe, Tiina

1998-01-01

Näiteid eestoi sisearhitektide ja firmade heast koostööst: Ene Eharanna ja Enn Lüüsi (ITC MCM) koostööst ERE Pangaga, Pille Lausmäe kujundustest Estconde-E'le, Maile Grünbergi tööst Linda Liinidele

Ostrich: Journal of African Ornithology - Vol 85, No 2 (2014)

African Journals Online (AJOL)

SHort Note Diet variability in the White Stork Ciconia ciconia in eastern Algeria · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Linda Cheriak, Christophe Barbraud, Salaheddine Doumandji, Slim Bouguessa. http://dx.doi.org/10.2989/00306525.2014.971451 ...

Oma isast kättemaksufilmi teinud kunstnik avas maalinäituse / Kaupo Meiel

Index Scriptorium Estoniae

Meiel, Kaupo, 1975-

2001-01-01

19. veebr. avas rootsi kunstnik Linda Västrik Pärnu Uue Kunsti Muuseumis oma arvutil tehtud skulptuurikavandite näituse "Valus vaikus", igal paaristunnil saab vaadata ka tema filmi "Isa ja mina". Samas ruumis on väljas ka belgia vaimupuudega kunstniku Thierry Degeyteri maalid

Baltimaade suurim, Põhjamaade moodsaim / Harri Treial

Index Scriptorium Estoniae

Treial, Harri

2000-01-01

1. märtsiks 2001. a. valmib Tallinnas Hobujaama tänavas 11 saali ja ligi 2000 istekohaga kobarkino. Arhitekt Andri Kirsima arhitektuuristuudiost Kirsima & Niineväli. Konstruktsioonid: OÜ Neoprojekt. Akustikainsener Linda Madalik. Peatöövõtja: Merko Ehitus, projektijuht Jüri Läll

Cinema Catalogue.

Science.gov (United States)

Lubovisk, Git, Ed.

This catalog lists some 14,600 books, magazines, photos and other material related to the film industry that are available from Larry Edmunds Bookshop Inc., Hollywood, Calif. The 488-page catalog is divided into eight sections. The first and largest section is labelled "Literature of the Cinema" and lists books in categories from aesthetics and…

Embracing E-Books: Increasing Students' Motivation to Read and Write

Science.gov (United States)

Siegle, Del

2012-01-01

In his keynote address at the "New York Times" Schools for Tomorrow 2011 Fall Conference, Dr. Larry Summers (2011) suggested that technology implementations have an unusual growth pattern. New technology innovations usually require more time to "catch on" than one might expect, but once they catch on, their use spreads more quickly than anyone can…

Lawrence G. Raisz November 13, 1925-August 25, 2010

NARCIS (Netherlands)

Bilezikian, J.P.; Drezner, M.; Kream, B.; Stern, P.; Clemens, T.; Elderkin, A.; Siris, E.; Krane, S.; Eisman, J.; Arnold, A.; Feyen, J.; Hurley, M.; Kawaguchi, H.; Lorenzo, J.; Peck, W.; Pilbeam, C.; Rowe, D.; Martin, T.J.; Hock, J.; DeLuca, H.; Rodan, S.; Lukert, B.; Chen, T.; Klein-Nulend, J.

2011-01-01

No one person in the world of bone has had a greater impact than Larry on us all. To honor his memory, we asked some of Larry’s closest friends and colleagues to reflect upon his extraordinary life. What follows is an expression of that meaning sprinkled with Larry’s inimitable wit and reflections

Dr. Mary McLeod Bethune: A Life Devoted to Service

Science.gov (United States)

Long, Kim Cliett

2011-01-01

The purpose of this paper is to explore and analyze the leadership traits of Dr. Mary McLeod Bethune, an African-American woman of history, using the servant leadership theory developed by Robert K. Greenberg and the ten characteristics of servant leadership as conceived by Larry C. Spears. This exploration seeks to identify the significant…

Comments: Improving Weighting Methods for Causal Mediation Analysis

Science.gov (United States)

Imai, Kosuke

2012-01-01

The author begins this discussion by thanking Larry Hedges, the editor of the journal, for giving him an opportunity to provide a commentary on this stimulating article. He also would like to congratulate the authors of the article for their insightful discussion on causal mediation analysis, which is one of the most important and challenging…

The Harmon Memorial Lectures in Military History 1959-1987

Science.gov (United States)

1988-01-01

Farrand, ed., Records of the Federal Convention of 1787 (New Haven, 1911-1937), 111, 85, 86n. 4. Pogue, Marshall, 1, 323; Larry 1. Bland and Sharon R...569, iU2, 573 Boulogne camp: 316, 317 594 INDEX Bourke , John G.: 26 Chamberlain, Neville: 572 Bradley, Omar N.: 163, 166, 167, 185, 190, Charles

Adjunctive levetiracetam in children, adolescents, and adults with primary generalized seizures: Open-label, noncomparative, multicenter, long-term follow-up study.

LENUS (Irish Health Repository)

Delanty, Norman

2012-02-01

Purpose: To evaluate the long-term efficacy and tolerability of adjunctive levetiracetam (LEV) in patients with uncontrolled idiopathic generalized epilepsy (IGE). Methods: This phase III, open-label, long-term, follow-up study (N167; NCT00150748) enrolled patients (4 to <65 years) with primary generalized seizures (tonic-clonic, myoclonic, absence). Patients received adjunctive LEV at individualized doses (1,000-4,000 mg\\/day; 20-80 mg\\/kg\\/day for children\\/adolescents weighing <50 kg). Efficacy results are reported for all seizure types [intention-to-treat (ITT) population, N = 217] and subpopulations with tonic-clonic (n = 152), myoclonic (n = 121), and\\/or absence (n = 70) seizures at baseline. Key Findings: One hundred twenty-five (57.6%) of 217 patients were still receiving treatment at the end of the study. Mean (standard deviation, SD) LEV dose was 2,917.5 (562.9) mg\\/day. Median (Q1-Q3) exposure to LEV was 2.1 (1.5-2.8) years, and the maximum duration was 4.6 years. Most patients were taking one (124\\/217, 57.1%) or >\\/=2 (92\\/217, 42.4%) concomitant antiepileptic drugs (AEDs). Seizure freedom of >\\/=6 months (all seizure types; primary efficacy end point) was achieved by 122 (56.2%) of 217 patients, and 49 (22.6%) of 217 patients had complete seizure freedom. Seizure freedom of >\\/=6 months from tonic-clonic, myoclonic, and absence seizures was achieved by 95 (62.5%) of 152, 75 (62.0%) of 121, and 44 (62.9%) of 70 patients, respectively. Mean (SD) maximum seizure freedom duration was 371.7 (352.4) days. At least one treatment-emergent adverse event (TEAE) was reported by 165 (76%) of 217 patients; most TEAEs were mild\\/moderate in severity, with no indication of an increased incidence over time. Seventeen (7.8%) of 217 patients discontinued medication because of TEAEs. The most common psychiatric TEAEs were depression (16\\/217, 7.4%), insomnia (9\\/217, 4.1%), nervousness (8\\/217, 3.7%), and anxiety (7\\/217, 3.2%). Significance: Adjunctive

Anthelmintic resistance and multidrug resistance in sheep gastro-intestinal nematodes in France, Greece and Italy.

Science.gov (United States)

Geurden, Thomas; Hoste, Herve; Jacquiet, Philippe; Traversa, Donato; Sotiraki, Smaragda; Frangipane di Regalbono, Antonio; Tzanidakis, Nikolaos; Kostopoulou, Despoina; Gaillac, Christie; Privat, Simon; Giangaspero, Annunziata; Zanardello, Claudia; Noé, Laura; Vanimisetti, Bindu; Bartram, David

2014-03-17

Anthelmintic resistance (AR) in ovine gastro-intestinal nematodes has been reported to affect the health and productivity of sheep globally. The objective of the present study was to evaluate the efficacy of commonly used oral drenches in sheep in France, Greece and Italy. In each country, 10 farms were selected. On each farm, 50 animals were blocked based on the pre-treatment faecal egg count (FEC). Within each block, animals were randomly allocated to one of 5 treatment groups. In addition to an untreated control group, there were 4 groups treated per oral route: moxidectin (MOX) and ivermectin (IVM), both at 0.2mg/kg bodyweight, levamisole (LEV; at 7.5mg/kg bodyweight) and a benzimidazole (BZ; at 3.75-5mg/kg bodyweight). In France, animals were not treated with LEV, but with netobimin (NET; at 7.5mg/kg bodyweight). The FEC was monitored using a modified McMaster technique. Two weeks after treatment, individual faecal samples were taken from all animals and efficacy was calculated as the difference between arithmetic mean FEC of the control group versus each respective treatment group. The results of the present study indicate the high efficacy of treatment with oral formulations of MOX (99-100%) and IVM (98-100%) on all farms, except on 1 farm in Greece. On this farm, multi drug resistance (MDR) was identified involving 4 anthelmintics (efficacy MOX: 91%; IVM: 0%; BZ: 58% and LEV: 87%). In Greece and Italy, AR against LEV and BZ was observed on some farms, with MDR involving both anthelmintics on 3 farms in Greece and on 2 farms in Italy. In France, AR against BZ and NET was observed on all 10 farms included. In all countries, Teladorsagia sp. was the most common nematode larva identified after treatment, followed by Haemonchus sp. and Trichostrongylus sp., with differences among farms and treatments. The current study confirms the high efficacy of oral treatments with MOX and IVM, even on farms with worm populations resistant to BZ, LEV or NET. This study also

«Mozart of psychology»

Directory of Open Access Journals (Sweden)

L.A. Verbitskaya

2016-09-01

Full Text Available The interview reveals the contribution of Lev Vygotsky in science and education, his main scientific achievements being drawn particular attention to. His innovative concepts in pedagogy and psychology are far ahead of time and are relevant up today. Lev Vygotsky put forward ideas that disclosed the principles of cultural development of human individual, his/her mental functions (speech, attention, thinking, and explained the internal mental processes of the child, their relationship with the environment. Lev Vygotsky introduced a number of terms and concepts that are the basis of modern psychology and pedagogy. Among them there are «higher mental functions», «interiorization», «mediation», «signification», etc. There extraordinary versatility Lev Vygotsky is emphasized in the paper. He is known not only as a psychologist, but also as a philosopher, methodologist, teacher, therapist, and even as the author of the brilliant theater and literary reviews. There are also facts about Vygotsky’s scientific path and his biography. The importance of Vygotsky’s ideas in the development of the educational process is highlighted. The scientist laid the most important principles of the child education. Such concepts developed by him as «zone of proximal development», «social situation of development», «critical age», «sensitive periods in the child development» are still successfully used by leading psychologists and educators. He made a huge contribution to the development of ideas about the origin and development of speech, its role in the development of thinking. The whole galaxy of prominent scientists were raised under the influence of Vygotsky. Closest students and colleagues were the author of the activity theory A.N. Leontyev, the world-renowned neuropsychologist A.R. Luria, the author of the concept of the child’s mental development D.B. El’konin, the author of the theory of stage development of mental activity P

High-Sensitivity Measurement of Density by Magnetic Levitation.

Science.gov (United States)

Nemiroski, Alex; Kumar, A A; Soh, Siowling; Harburg, Daniel V; Yu, Hai-Dong; Whitesides, George M

2016-03-01

This paper presents methods that use Magnetic Levitation (MagLev) to measure very small differences in density of solid diamagnetic objects suspended in a paramagnetic medium. Previous work in this field has shown that, while it is a convenient method, standard MagLev (i.e., where the direction of magnetization and gravitational force are parallel) cannot resolve differences in density mm) because (i) objects close in density prevent each other from reaching an equilibrium height due to hard contact and excluded volume, and (ii) using weaker magnets or reducing the magnetic susceptibility of the medium destabilizes the magnetic trap. The present work investigates the use of weak magnetic gradients parallel to the faces of the magnets as a means of increasing the sensitivity of MagLev without destabilization. Configuring the MagLev device in a rotated state (i.e., where the direction of magnetization and gravitational force are perpendicular) relative to the standard configuration enables simple measurements along the axes with the highest sensitivity to changes in density. Manipulating the distance of separation between the magnets or the lengths of the magnets (along the axis of measurement) enables the sensitivity to be tuned. These modifications enable an improvement in the resolution up to 100-fold over the standard configuration, and measurements with resolution down to 10(-6) g/cm(3). Three examples of characterizing the small differences in density among samples of materials having ostensibly indistinguishable densities-Nylon spheres, PMMA spheres, and drug spheres-demonstrate the applicability of rotated Maglev to measuring the density of small (0.1-1 mm) objects with high sensitivity. This capability will be useful in materials science, separations, and quality control of manufactured objects.

Psychiatric and behavioral side effects of anti-epileptic drugs in adolescents and children with epilepsy.

Science.gov (United States)

Chen, B; Detyniecki, K; Choi, H; Hirsch, L; Katz, A; Legge, A; Wong, R; Jiang, A; Buchsbaum, R; Farooque, P

2017-05-01

The objective of the study was to compare the psychiatric and behavioral side effect (PBSE) profiles of both older and newer antiepileptic drugs (AEDs) in children and adolescent patients with epilepsy. We used logistic regression analysis to test the correlation between 83 non-AED/patient related potential predictor variables and the rate of PBSE. We then compared for each AED the rate of PBSEs and the rate of PBSEs that led to intolerability (IPBSE) while controlling for non-AED predictors of PBSEs. 922 patients (≤18 years old) were included in our study. PBSEs and IPBSEs occurred in 13.8% and 11.2% of patients, respectively. Overall, a history of psychiatric condition, absence seizures, intractable epilepsy, and frontal lobe epilepsy were significantly associated with increased PBSE rates. Levetiracetam (LEV) had the greatest PBSE rate (16.2%). This was significantly higher compared to other AEDs. LEV was also significantly associated with a high rate of IPBSEs (13.4%) and dose-decrease rates due to IPBSE (6.7%). Zonisamide (ZNS) was associated with significantly higher cessation rate due to IPBSE (9.1%) compared to other AEDs. Patients with a history of psychiatric condition, absence seizures, intractable epilepsy, or frontal lobe epilepsy are more likely to develop PBSE. PBSEs appear to occur more frequently in adolescent and children patients taking LEV compared to other AEDs. LEV-attributed PBSEs are more likely to be associated with intolerability and subsequent decrease in dose. The rate of ZNS-attributed IPBSEs is more likely to be associated with complete cessation of AED. Copyright © 2017 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

Unsteady flow challenges tracking performance at vortex shedding frequencies without disrupting lift mechanisms

Science.gov (United States)

Matthews, Megan; Sponberg, Simon

2017-11-01

Birds, insects, and many animals use unsteady aerodynamic mechanisms to achieve stable hovering flight. Natural environments are often characterized by unsteady flows causing animals to dynamically respond to perturbations while performing complex tasks, such as foraging. Little is known about how unsteady flow around an animal interacts with already unsteady flow in the environment or how this impacts performance. We study how the environment impacts maneuverability to reveal any coupling between body dynamics and aerodynamics for hawkmoths, Manduca sexta,tracking a 3D-printed robotic flower in a wind tunnel. We also observe the leading-edge vortex (LEV), a known lift-generating mechanism for insect flight with smoke visualization. Moths in still and unsteady air exhibit near perfect tracking at low frequencies, but tracking in the flower wake results in larger overshoot at mid-range. Smoke visualization of the flower wake shows that the dominant vortex shedding corresponds to the same frequency band as the increased overshoot. Despite the large effect on flight dynamics, the LEV remains bound to the wing and thorax throughout the wingstroke. In general, unsteady wind seems to decrease maneuverability, but LEV stability seems decoupled from changes in flight dynamics.

Sustainable Management of Oleaginous Trees as a Source for Renewable Energy Supply and Climate Change Mitigation: A Case Study in China

Directory of Open Access Journals (Sweden)

Jin Zhang

2018-05-01

Full Text Available Forests provide a range of ecosystem services, including bioenergy supply and carbon sequestration, both contributing to significant climate change mitigation. Oleaginous trees have potential to provide bioenergy supplies through biodiesel-producing seed yield as well as contributing to carbon sequestration. This paper aims to show the provisions of bioenergy and carbon savings through forest rotation management and it will investigate the potential of oleaginous forest management in China. We use the land expectation value (LEV model to calculate the optimal joint values of timber, seed and total carbon savings, including carbon sequestration from forest and carbon reductions through energy substitutions. The results indicate that combining both values of seeds and carbon savings increase the LEV and rotation age (167,611 Yuan/ha, 78 years compared to sole timber value (26,053 Yuan/ha, 55 years. The optimization of the LEVs and the resulting optimal rotation ages are significantly sensitive to the discounting rate. Annual biodiesel potential production from Pistacia chinensis can take up 1.7% of the national diesel consumption in China. We conclude that China can use improved forest rotation management as an effective means for achieving goals in its low-carbon energy strategy.

Tilted Magnetic Levitation Enables Measurement of the Complete Range of Densities of Materials with Low Magnetic Permeability.

Science.gov (United States)

Nemiroski, Alex; Soh, Siowling; Kwok, Sen Wai; Yu, Hai-Dong; Whitesides, George M

2016-02-03

Magnetic levitation (MagLev) of diamagnetic or weakly paramagnetic materials suspended in a paramagnetic solution in a magnetic field gradient provides a simple method to measure the density of small samples of solids or liquids. One major limitation of this method, thus far, has been an inability to measure or manipulate materials outside of a narrow range of densities (0.8 g/cm(3) MagLev"-to increase the range of densities that can be levitated magnetically. Tilting the MagLev device relative to the gravitational vector enables the magnetic force to be decreased (relative to the magnetic force) along the axis of measurement. This approach enables many practical measurements over the entire range of densities observed in matter at ambient conditions-from air bubbles (ρ ≈ 0) to osmium and iridium (ρ ≈ 23 g/cm(3)). The ability to levitate, simultaneously, objects with a broad range of different densities provides an operationally simple method that may find application to forensic science (e.g., for identifying the composition of miscellaneous objects or powders), industrial manufacturing (e.g., for quality control of parts), or resource-limited settings (e.g., for identifying and separating small particles of metals and alloys).

Antibacterial and Synergy of Berberines with Antibacterial Agents against Clinical Multi-Drug Resistant Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA

Directory of Open Access Journals (Sweden)

Zhong-Qi Bian

2012-08-01

Full Text Available Antibacterial activity of berberine (Ber and 8-acetonyl-dihydroberberine (A-Ber alone and combined uses with antibacterial agents ampicillin (AMP, azithromycin (AZM, cefazolin (CFZ and levofloxacin (LEV was studied on 10 clinical isolates of SCCmec III type methicillin-resistant Staphylococcus aureus (MRSA. Susceptibility to each agent alone was tested using a broth microdilution method and the chequerboard and time-kill tests for the combined evaluations, respectively. The alone MICs/MBCs (mg/mL ranges were 32–128/64–256 (Ber and 32-128/128-512 (A-Ber. Significant synergies were observed for the Ber (A-Ber/AZM and Ber (A-Ber/LEV combinations against 90% of the tested MRSA strains, with fractional inhibitory concentration indices (FICIs values ranged  from 0.188 to 0.500. An additivity result was also observed for the Ber/AZM combination by time-kill curves. These results demonstrated for the first time that Ber and A-Ber enhanced the in vitro inhibitory efficacy of AZM and LEV to a same extent, which had potential for further investigation in combinatory therapeutic applications of patients infected with MRSA.

South African Journal of Animal Science - Vol 18, No 4 (1988)

African Journals Online (AJOL)

DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. LG Ekermans, HH Meissner, C Maree, Linda du Plessis, 128-136 ... Mathematical programming model for the optimization of nutritional strategy for a dairy cow · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

Arhitektuuripoliitiliselt Jõhvi kontserdimajast = Jõhvi concert house from the point of architecture policy / Ingrid Ruudi

Index Scriptorium Estoniae

Ruudi, Ingrid, 1978-

2006-01-01

Projekteerija: AB Luhse & Tuhal OÜ. Arhitektid Ra Luhse, Tanel Tuhal. Sisekujundus: Aivar Oja, Mareliis Raid. Konstruktor: IB Pike OÜ. Insener-akustik Linda Madalik. Ehitusfirma: AS YIT Ehitus. Projekt 2003, valmis 2005. Ill.: I ja II korruse plaan, lõige, välisvaade, 2 sisevaadet, värv

75 FR 47029 - Submission for OMB Review; Comment Request

Science.gov (United States)

2010-08-04

..., with applicable supporting documentation; including, among other things, a description of the likely... Web site at http://www.reginfo.gov/public/do/PRAMain or by contacting Linda Watts Thomas on 202-693... needed to determine entitlement to benefits under the EEOICPA. For additional information, see related...

75 FR 47630 - Submission for OMB Review; Comment Request

Science.gov (United States)

2010-08-06

..., with applicable supporting documentation; including, among other things, a description of the likely... Web site at http://www.reginfo.gov/public/do/PRAMain or by contacting Linda Watts Thomas on 202-693... information needed to determine entitlement to benefits under the EEOICPA. For additional information, see...

76 FR 27653 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2011-05-12

... Southpoint, 7007 Fayetteville Road, Durham, NC 27713. Contact Person: Linda K. Bass, PhD, Scientific Review... Estimation--Health Risks from Environmental Exposures; 93.142, NIEHS Hazardous Waste Worker Health and Safety Training; 93.143, NIEHS Superfund Hazardous Substances--Basic Research and Education; 93.894, Resources and...

Eesti Teatriliidu aastapreemiad 1996

Index Scriptorium Estoniae

1997-01-01

Aleksander Kurtna nim. preemia sai Anne Lange (T. S. Elioti, J. B. Priestley, W. Shakespeare'i, A. Milleri, E. J. Dunsany ja T. Kushneri näidendite tõlkimise eest); Priit Põldroosi nim. preemia sai Lilian Tamm (Vellerand) raamatu 'Linda Rummo. Elust ja lavaelust' koostamise eest

76 FR 35225 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2011-06-16

... Health Sciences Special Emphasis Panel, Pathway to Independence/Career Development. Date: July 14, 2011. Time: 11 a.m. to 2:25 p.m. Agenda: To review and evaluate grant applications. Place: NIEHS/National... Conference Call). Contact Person: Linda K. Bass, PhD, Scientific Review Administrator, Scientific Review...