WorldWideScience

Sample records for largest population center

  1. Alternative Fuels Data Center: America's Largest Home Runs on Biodiesel in

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    North Carolina America's Largest Home Runs on Biodiesel in North Carolina to someone by E-mail Share Alternative Fuels Data Center: America's Largest Home Runs on Biodiesel in North Carolina on Facebook Tweet about Alternative Fuels Data Center: America's Largest Home Runs on Biodiesel in North

  2. Indication and implementation of lipidapheresis, rheopheresis, or immunoadsorption (lessons learnt from Germany's largest apheresis center).

    Science.gov (United States)

    Heigl, Franz; Hettich, Reinhard; Lotz, Norbert; Reeg, Harduin; Eder, Bernadette; Steckholzer-Kroth, Karin; Browatzki, Michael; Harre, Kerstin; Arendt, Rainer

    2009-12-29

    Efficient modes of extracorporeal blood purification are available today for apheresis treatment of progressive atherosclerosis, autoimmune disease, or for improving hemorheology. Advanced technology and sophisticated care render apheresis treatment selective, safe and tolerable. Our task is to constantly update indications for apheresis based on best evidence available and good clinical practice, as well as, to determine how apheresis therapy can be made available to those in need or with otherwise refractory disease. Presenting examples of lipid apheresis, rheopheresis, or immunoadsorption for treatment of hypercholesterolemia, hyperlipoproteinemia (a), acute hearing loss, refractory or exacerbating multiple sclerosis, we highlight real world obstacles for implementation of treatment, resulting in still too many patients with proven or recommended indication left untreated. Based on the experience of the largest apheresis center in Germany, with more than 3,300 treatments per year, we depict the necessary structure for identification of patients, defining indication, referral, implementation of therapy, and reimbursement. Apheresis is unfamiliar to most patients and many practitioners or consultants. Nephrologists, performing >90% of apheresis treatments in Germany, have to form a network for referral comprising all regional care-givers, general practitioners as well as the respective specialists (mainly, cardiologists, endocrinologists, diabetologists, ORL specialists, neurologists, ophthalmologists, or rheumatologists), and insurances or other cost-bearing parties for offering a scientifically approved therapeutic regimen and comprehensive care. We have realized this concept in a high volume apheresis center acting in a closely knit network characterized by an unrelenting effort at ongoing medical education. As a consequence, we include approximately 10 times more patients with appropriate diagnoses in our apheresis program as compared to the national average

  3. Largest case series of Latin American eyelid tumors over 13-Years from a single center in Sao Paulo, Brazil

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    Jéssica Carolinne Damasceno

    Full Text Available ABSTRACT Purpose: Malignant lesions of the eyelid are the most common eye cancers. Although rarely lethal, late diagnosis can lead to serious visual morbidity. Definitive diagnosis of neoplastic lesions is pathological. Indications and types of eyelid lesions in a single high-volume ophthalmic reference center in Sao Paulo, Brazil, were analyzed. Methods: The surgical pathological reports of patients who underwent eye removal procedures between January 2000 and December 2012 were retrieved from the electronic database of the Ophthalmology Department and retrospectively reviewed. Data regarding the final anatomopathological diagnosis, sex, and age were analyzed via the χ2 test with Yates' correction. Results: Of the 1,113 eyelid tumors resected over the 13-year study period, 324 (29% lesions were malignant. The most prevalent lesions were basal cell, squamous cell, and sebaceous gland carcinomas. The median ages of patients (females, n=165, 51%; males, n=159, 49% with a diagnosis of basal cell, squamous cell, and sebaceous gland carcinomas were 65, 75, and 70 years, respectively. Conclusion: This is the largest retrospective cohort analysis of eyelid tumors in a Latin American population. These findings are in agreement with those from large centers in other countries and regions.

  4. Nature Appropriation and Associations with Population Health in Canada’s Largest Cities

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    Timothy Jason

    2013-03-01

    Full Text Available Earth is a finite system with a limited supply of resources. As the human population grows, so does the appropriation of Earth’s natural capital, thereby exacerbating environmental concerns such as biodiversity loss, increased pollution, deforestation and global warming. Such concerns will negatively impact human health although it is widely believed that improving socio-economic circumstances will help to ameliorate environmental impacts and improve health outcomes. However, this belief does not explicitly acknowledge the fact that improvements in socio-economic position are reliant on increased inputs from nature. Gains in population health, particularly through economic means, are disconnected from the appropriation of nature to create wealth so that health gains become unsustainable. The current study investigated the sustainability of human population health in Canada with regard to resource consumption or “ecological footprints” (i.e., the resources required to sustain a given population. Ecological footprints of the 20 largest Canadian cities, along with several important determinants of health such as income and education, were statistically compared with corresponding indicators of human population health outcomes. A significant positive relationship was found between ecological footprints and life expectancy, as well as a significant negative relationship between ecological footprints and the prevalence of high blood pressure. Results suggest that increased appropriation of nature is linked to improved health outcomes. To prevent environmental degradation from excessive appropriation of natural resources will require the development of health promotion strategies that are de-coupled from ever-increasing and unsustainable resource use. Efforts to promote population health should focus on health benefits achieved from a lifestyle based on significantly reduced consumption of natural resources.

  5. Enhanced natural radiation exposure enhanced by human activity: the largest contributor to the Chinese population dose

    International Nuclear Information System (INIS)

    Pan Ziqiang; Liu Yanyang

    2011-01-01

    For the radiation exposure caused by human activities, the enhanced natural radiation exposure is the largest contributor to Chinese population dose. This problem has attracted social attention in recent years. Efforts have been made in several fields, such as radon indoors and in workplace, environmental problems associated with NORMs, occupational radiation hazards of non-uranium mine, and radiation dose evaluation for energy chain, but there are still many problems to be solved. In order to protect the health of workers and the public, while ensuring industrial production and economic development, it is also necessary to continue to strengthen research in all aspects above mentioned, and gradually promote the control of natural radiation exposure enhanced by human activities. (authors)

  6. CERN: Digital image analysis in the world's largest research center for particle physics

    CERN Multimedia

    2005-01-01

    Those interested in researching into the smallest building blocks that matter is made up of need the largest instruments. CERN, near Geneva, Switzerland is where the most powerful circular accelerator in the world is being built: the Large Hadron Collider (LHC) for proton collisions. It has a circumference of 26.7 km (4 pages)

  7. Invertebrate population genetics across Earth's largest habitat: The deep-sea floor.

    Science.gov (United States)

    Taylor, M L; Roterman, C N

    2017-10-01

    Despite the deep sea being the largest habitat on Earth, there are just 77 population genetic studies of invertebrates (115 species) inhabiting non-chemosynthetic ecosystems on the deep-sea floor (below 200 m depth). We review and synthesize the results of these papers. Studies reveal levels of genetic diversity comparable to shallow-water species. Generally, populations at similar depths were well connected over 100s-1,000s km, but studies that sampled across depth ranges reveal population structure at much smaller scales (100s-1,000s m) consistent with isolation by adaptation across environmental gradients, or the existence of physical barriers to connectivity with depth. Few studies were ocean-wide (under 4%), and 48% were Atlantic-focused. There is strong emphasis on megafauna and commercial species with research into meiofauna, "ecosystem engineers" and other ecologically important species lacking. Only nine papers account for ~50% of the planet's surface (depths below 3,500 m). Just two species were studied below 5,000 m, a quarter of Earth's seafloor. Most studies used single-locus mitochondrial genes revealing a common pattern of non-neutrality, consistent with demographic instability or selective sweeps; similar to deep-sea hydrothermal vent fauna. The absence of a clear difference between vent and non-vent could signify that demographic instability is common in the deep sea, or that selective sweeps render single-locus mitochondrial studies demographically uninformative. The number of population genetics studies to date is miniscule in relation to the size of the deep sea. The paucity of studies constrains meta-analyses where broad inferences about deep-sea ecology could be made. © 2017 The Authors. Molecular Ecology Published by John Wiley & Sons Ltd.

  8. Reconstructing the population history of the largest tribe of India: the Dravidian speaking Gond.

    Science.gov (United States)

    Chaubey, Gyaneshwer; Tamang, Rakesh; Pennarun, Erwan; Dubey, Pavan; Rai, Niraj; Upadhyay, Rakesh Kumar; Meena, Rajendra Prasad; Patel, Jayanti R; van Driem, George; Thangaraj, Kumarasamy; Metspalu, Mait; Villems, Richard

    2017-04-01

    The Gond comprise the largest tribal group of India with a population exceeding 12 million. Linguistically, the Gond belong to the Gondi-Manda subgroup of the South Central branch of the Dravidian language family. Ethnographers, anthropologists and linguists entertain mutually incompatible hypotheses on their origin. Genetic studies of these people have thus far suffered from the low resolution of the genetic data or the limited number of samples. Therefore, to gain a more comprehensive view on ancient ancestry and genetic affinities of the Gond with the neighbouring populations speaking Indo-European, Dravidian and Austroasiatic languages, we have studied four geographically distinct groups of Gond using high-resolution data. All the Gond groups share a common ancestry with a certain degree of isolation and differentiation. Our allele frequency and haplotype-based analyses reveal that the Gond share substantial genetic ancestry with the Indian Austroasiatic (ie, Munda) groups, rather than with the other Dravidian groups to whom they are most closely related linguistically.

  9. City-ecological perspectives of the development of high urbanized multifunctional centers of the largest Russian cities

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    Kolesnikov Sergey Anatol’evich

    2015-01-01

    Full Text Available This article presents some results of the author’s dissertation research dedicated to formation of an architectural typology of high urbanized multifunctional units of urban structure of the largest cities (further HUMUUS as centers of social activity, which include buildings, constructions, transportation equipment and open spaces, where human flows transpose, start and end with the purpose of bringing into this space a concentrated maximum of goods, services and information with minimum time expenditures. This article draws attention to the development analysis of the structure-forming functions of HUMUUS and their town planning and environmental impact on the surrounding area. The study of planning structures of the largest Russian cities (Samara, Kazan, Nizhny Novgorod made it possible to identify a number of main objects, in which structure-forming functions of HUMUUS are materialized: railroad complex (historically formed, developed, dominated, system-wide road junction, transport interchange hub (providing intraurban messages, public office and business centers, leisure and entertainment centers, shopping centers. Basing on researches of Russian and foreign experience, it is possible to predict with full confidence the following trends and streams of environmental and urban development of HUMUUS in the near-term perspective: Strengthening of the environmental and urban frame by network evolution of HUMUUS; Inclusion of green areas of HUMUUS in the system of citywide green areas; Increment of the interest of the investors to the public road junction for the purpose of reorganization of them to full HUMUUS with all characteristics of high-urbanized and environmental and urban reorganization (separation of traffic and pedestrian flows, maximum capacity, multiple-level system, multifunctional, increase in landscaped green space, reconstruction of engineering systems and communications, the use of modern ecological building designs and

  10. Demography and viability of the largest population of greater one-horned rhinoceros in Nepal

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    Naresh Subedi

    2017-10-01

    Full Text Available Megaherbivores are characterized by slow life history traits which when coupled with human exploitation makes them vulnerable to local extinctions. An understanding of key demographic parameters assists in guiding management interventions to ensure their recovery and persistence over the longer term. We monitored 110 (30 calves, 80 young and adults individually known greater one-horned rhinoceros (Rhinoceros unicornis for seven years in Chitwan National Park, Nepal (2009–15. Using known fate model with staggered entry design in program MARK we estimated annual calf survival at 0.765 ± 0.026 SE and that of remaining older age groups between 0.96 and 0.985. Both genders exhibited a typical Type I survivorship curve. The population consisted of 62% adults, 13% sub-adults and 26% juveniles and calves (dependent animals. The adult sex ratio (female: male was 1.23 ± 0.09 SE and dependent: cow ratio was 0.636 ± 0.03 SE. Age at first calving was 7.91 years ± 0.31 SE. Shorter inter-calving intervals were observed for young adults compared to old adults. Overall inter-calving interval was 41.28 months ± 2.33 SE. Chitwan rhino population grew at a maximum realized rate of r = 0.051 ± 0.005 SE. PHVA results showed that low level continuous poaching increased extinction probability compared to high but intermittent poaching episodes. An increase in annual poaching of over six females and 12 males over the current average of 5.5 rhinos per year, coupled with habitat degradation, caused by the alien invasive Mikania micrantha resulted in high extinction risks. Annually upto 13 rhinos (8 males and 5 females from Chitwan can be used for reintroduction and supplementation of rhinoceros across their current and historic range.

  11. The epidemiological trends of head injury in the largest Canadian adult trauma center from 1986 to 2007.

    Science.gov (United States)

    Cadotte, David W; Vachhrajani, Shobhan; Pirouzmand, Farhad

    2011-06-01

    This study documents the epidemiology of head injury over the course of 22 years in the largest Level I adult trauma center in Canada. This information defines the current state, changing pattern, and relative distribution of demographic factors in a defined group of trauma patients. It will aid in hypothesis generation to direct etiological research, administrative resource allocation, and preventative strategies. Data on all the trauma patients treated at Sunnybrook Health Sciences Centre (SHSC) from 1986 to 2007 were collected in a consecutive, prospective fashion. The authors reviewed these data from the Sunnybrook Trauma Registry Database in a retrospective fashion. The aggregate data on head injury included demographic data, cause of injury, and Injury Severity Score (ISS). The collected data were analyzed using univariate techniques to depict the trend of variables over years. The authors used the length of stay (LOS) and number of deaths per year (case fatality rate) as crude measures of outcome. A total of 16,678 patients were treated through the Level I trauma center at SHSC from January 1986 to December 2007. Of these, 9315 patients met the inclusion criteria (ISS > 12, head Abbreviated Injury Scale score > 0). The median age of all trauma patients was 36 years, and 69.6% were male. The median ISS of the head-injury patients was 27. The median age of this group of patients increased by 12 years over the study period. Motorized vehicle accidents accounted for the greatest number of head injuries (60.3%) although the relative percentage decreased over the study period. The median transfer time of patients sustaining a head injury was 2.58 hours, and there was an approximately 45 minute improvement over the 22-year study period. The median LOS in our center decreased from 19 to 10 days over the study period. The average case fatality rate was 17.4% over the study period. In multivariate analysis, more severe injuries were associated with increased LOS as

  12. Health Education Research and Practice Literature on Hispanic Health Issues: Have We Lost Sight of the Largest Minority Population?

    Science.gov (United States)

    Price, James H; Khubchandani, Jagdish

    2016-03-01

    Hispanics constitute the largest racial/ethnic minority population in the United States and are the fastest growing segment of the population. Knowledge about health needs and practices, effective health promotion programs, and health policy making for Hispanics has the potential to improve population health outcomes for this group. Continued research and practice literature will aid in accomplishing these objectives. However, little is known about the extent of health education-related literature available on Hispanic health issues. In this review, we analyzed research and practice publications in all health education-related journals to assess the volume of articles published on Hispanic health issues. We found that the portion of journal articles devoted to Hispanic health issues varied widely among the journals and that there was a very limited emphasis on Hispanic health-related issues. Journal editors and editorial board members may need to be more proactive in soliciting manuscripts on Hispanic health, and our practitioners may have to improve their professional skills and cultural competence in order to work with Hispanic populations to produce research and practice literature that is of adequate quantity and quality to help improve Hispanics' health. © 2016 Society for Public Health Education.

  13. [Detection of the largest population susceptible to prescription of a program of exercises in Primary Care to prevent frailty].

    Science.gov (United States)

    Rosas Hernández, Ana María; Alejandre Carmona, Sergio; Rodríguez Sánchez, Javier Enrique; Castell Alcalá, Maria Victoria; Otero Puime, Ángel

    2018-03-16

    Identify the population over 70 year's old treated in primary care who should participate in a physical exercise program to prevent frailty. Analyze the concordance among 2criteria to select the beneficiary population of the program. Population-based cross-sectional study. Primary Care. Elderly over 70 years old, living in the Peñagrande neighborhood (Fuencarral district of Madrid) from the Peñagrande cohort, who accepted to participate in 2015 (n = 332). The main variable of the study is the need for exercise prescription in people over 70 years old at the Primary Care setting. It was identified through 2different definitions: Prefrail (1-2 of 5 Fried criteria) and Independent individuals with physical performance limited, defined by Consensus on frailty and falls prevention among the elderly (independent and with a total SPPB score <10). The 63,8% of participants (n = 196) need exercise prescription based on criteria defined by Fried and/or the consensus for prevention of frailty and falls in the elderly. In 82 cases the 2criteria were met, 80 were prefrail with normal physical performance and 34 were robust with a limited physical performance. The concordance among both criteria is weak (kappa index 0, 27). Almost 2thirds of the elderly have some kind of functional limitation. The criteria of the consensus document to prevent frailty detect half of the pre-frail individuals in the community. Copyright © 2018 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.

  14. The population genetics of Quechuas, the largest native South American group: autosomal sequences, SNPs, and microsatellites evidence high level of diversity.

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    Scliar, Marilia O; Soares-Souza, Giordano B; Chevitarese, Juliana; Lemos, Livia; Magalhães, Wagner C S; Fagundes, Nelson J; Bonatto, Sandro L; Yeager, Meredith; Chanock, Stephen J; Tarazona-Santos, Eduardo

    2012-03-01

    Elucidating the pattern of genetic diversity for non-European populations is necessary to make the benefits of human genetics research available to individuals from these groups. In the era of large human genomic initiatives, Native American populations have been neglected, in particular, the Quechua, the largest South Amerindian group settled along the Andes. We characterized the genetic diversity of a Quechua population in a global setting, using autosomal noncoding sequences (nine unlinked loci for a total of 16 kb), 351 unlinked SNPs and 678 microsatellites and tested predictions of the model of the evolution of Native Americans proposed by (Tarazona-Santos et al.: Am J Hum Genet 68 (2001) 1485-1496). European admixture is Quechua or Melanesian populations, which is concordant with the African origin of modern humans and the fact that South America was the last part of the world to be peopled. The diversity in the Quechua population is comparable with that of Eurasian populations, and the allele frequency spectrum based on resequencing data does not reflect a reduction in the proportion of rare alleles. Thus, the Quechua population is a large reservoir of common and rare genetic variants of South Amerindians. These results are consistent with and complement our evolutionary model of South Amerindians (Tarazona-Santos et al.: Am J Hum Genet 68 (2001) 1485-1496), proposed based on Y-chromosome data, which predicts high genomic diversity due to the high level of gene flow between Andean populations and their long-term effective population size. Copyright © 2012 Wiley Periodicals, Inc.

  15. Large population center and core melt accident considerations in siting

    International Nuclear Information System (INIS)

    Camarinopoulos, L.; Yadigaroglu, G.

    1983-01-01

    The problem of providing suitable demographic siting criteria in the presence of a very large population center in an otherwise sparsely populated region is addressed. Simple calculations were performed making maximum use of pretabulated results of studies where core melt accidents are considered. These show that taking into consideration the air flow patterns in the region can lower the expected population doses from core melt accidents more effectively than distance alone. Expected doses are compared to the annual background radiation dose. A simple siting criterion combining geographical considerations with the probability of a release reaching the large population center is proposed

  16. 10 CFR 100.11 - Determination of exclusion area, low population zone, and population center distance.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Determination of exclusion area, low population zone, and population center distance. 100.11 Section 100.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REACTOR... and for Testing Reactors § 100.11 Determination of exclusion area, low population zone, and population...

  17. How does Australia's largest dolphin-watching industry affect the behaviour of a small and resident population of Indo-Pacific bottlenose dolphins?

    Science.gov (United States)

    Steckenreuter, Andre; Möller, Luciana; Harcourt, Robert

    2012-04-30

    The small, genetically distinct population of Indo-Pacific bottlenose dolphins (Tursiops aduncus) in Port Stephens, New South Wales (NSW), is the target of the largest dolphin-watching industry in Australia and is located within the Port Stephens - Great Lakes Marine Park that was created in 2005. The effects of this industry have been identified as of significant management importance by the Marine Parks Authority NSW. Accordingly, the impact of commercial dolphin-watching boats was investigated from boat-based surveys from August 2008 to August 2009. Presence of dolphin-watching boats altered both the dolphins' behavioural states and activity budgets. Dolphins spent 66.5% less time feeding and 44.2% less time socialising, spent four times more milling, and were never observed to rest in the presence of dolphin-watching boats. Moreover, dolphin groups were more cohesive during dolphin-watching boat encounters and dolphins tended to avoid tour boats. These effects were exacerbated as the number of boats increased and the distance from boats decreased. The rate of approach was high with boats approaching each dolphin group three times per day in winter and six times in summer. Moreover, groups of dolphins with newborns were approached closer than state regulated minimum approach distances in nine out of ten encounters. Globally, dolphin-watching industries frequent small resident groups of coastal dolphins and effects are likely to be similar. We suggest that existing controls are inadequate and that these together with additional regulations be enforced by a regular presence of authorities. We suggest no more than one dolphin-watching boat within 50 m of a group of dolphins, or 100 m if calves are present. Operating times of dolphin-watching boats should be restricted in numbers after 1 pm, i.e., during preferred foraging times for dolphins. Additionally, exclusion zones should be considered to reduce pressure on dolphins undertaking critical activities such as

  18. Aye-aye population genomic analyses highlight an important center of endemism in northern Madagascar.

    Science.gov (United States)

    Perry, George H; Louis, Edward E; Ratan, Aakrosh; Bedoya-Reina, Oscar C; Burhans, Richard C; Lei, Runhua; Johnson, Steig E; Schuster, Stephan C; Miller, Webb

    2013-04-09

    We performed a population genomics study of the aye-aye, a highly specialized nocturnal lemur from Madagascar. Aye-ayes have low population densities and extensive range requirements that could make this flagship species particularly susceptible to extinction. Therefore, knowledge of genetic diversity and differentiation among aye-aye populations is critical for conservation planning. Such information may also advance our general understanding of Malagasy biogeography, as aye-ayes have the largest species distribution of any lemur. We generated and analyzed whole-genome sequence data for 12 aye-ayes from three regions of Madagascar (North, West, and East). We found that the North population is genetically distinct, with strong differentiation from other aye-ayes over relatively short geographic distances. For comparison, the average FST value between the North and East aye-aye populations--separated by only 248 km--is over 2.1-times greater than that observed between human Africans and Europeans. This finding is consistent with prior watershed- and climate-based hypotheses of a center of endemism in northern Madagascar. Taken together, these results suggest a strong and long-term biogeographical barrier to gene flow. Thus, the specific attention that should be directed toward preserving large, contiguous aye-aye habitats in northern Madagascar may also benefit the conservation of other distinct taxonomic units. To help facilitate future ecological- and conservation-motivated population genomic analyses by noncomputational biologists, the analytical toolkit used in this study is available on the Galaxy Web site.

  19. Largest College Endowments, 2011

    Science.gov (United States)

    Chronicle of Higher Education, 2012

    2012-01-01

    Of all endowments valued at more than $250-million, the UCLA Foundation had the highest rate of growth over the previous year, at 49 percent. This article presents a table of the largest college endowments in 2011. The table covers the "rank," "institution," "market value as of June 30, 2011," and "1-year change" of institutions participating in…

  20. Sweden's largest Facebook study

    OpenAIRE

    Denti, Leif; Barbopoulus, Isak; Nilsson, Ida; Holmberg, Linda; Thulin, Magdalena; Wendeblad, Malin; Andén, Lisa; Davidsson, Emelie

    2012-01-01

    The emergence of the Internet has made it easier for people to socially interact than ever before. Today, the most popular channel is Facebook with over 845 million users world wide. In Sweden, the number of users amount to approximately half of the population. We had two aims with this study. First, we investigate which areas of Facebook usage that Swedish Facebook users consider more important vis-a-vis less important. We were also interested in how users convey their persona through t... m...

  1. Plans to Develop a Gas Field in the Kansu on the Border of the Usturt State Nature Reserve is a Real Threat for the Ecosystem of the Reserve and Largest Population of the Saker Falcon in Kazakhstan

    Directory of Open Access Journals (Sweden)

    Mark V. Pestov

    2016-02-01

    Full Text Available Plans of JSC “KazMunayGaz” National Company” on developing the Kansu gas field, which is situated right next to current southern borders of Usturt natural reserve on Kenderli-Kayasan conservation zone (Mangystau Province of the Republic of Kazakhstan are a direct danger for the largest population of the Saker Falcon Falco cherrug korelovi in Kazakhstan and for Kenderli-Kayasan conservation zone’s ecosystem as a whole. On the contrary, the realization of plans to expand the Usturt State Reserve within the Government of the Republic of Kazakhstan/GEF/UNDP project “Rising of stability of systems in conservation territories in desert ecosystems through promoting life sustaining sources compatible with biodiversity in and around conservation areas” and international expert group’s initiative of Mangystau Protected Area System to be nominated for UNESCO World Heritage status could create favorable environment for Usturt population of the Saker Falcon. It’s evident that all possible outcomes should be taken into account in the long-term planning of future development of Mangystau region, and options of development with less negative effect on environment should be chosen. In their letter to President of Kazakhstan the experts described their opinion on the necessity of imposing a moratorium on exploration and development of the Kansu gas field and concentrating on alternative fields.

  2. Largest particle detector nearing completion

    CERN Multimedia

    2006-01-01

    "Construction of another part of the Large Hadron Collider (LHC), the worl's largest particle accelerator at CERN in Switzerland, is nearing completion. The Compact Muon Solenoid (CMS) is oner of the LHC project's four large particle detectors. (1/2 page)

  3. Population-based geographic access to parent and satellite National Cancer Institute Cancer Center Facilities.

    Science.gov (United States)

    Onega, Tracy; Alford-Teaster, Jennifer; Wang, Fahui

    2017-09-01

    Satellite facilities of National Cancer Institute (NCI) cancer centers have expanded their regional footprints. This study characterized geographic access to parent and satellite NCI cancer center facilities nationally overall and by sociodemographics. Parent and satellite NCI cancer center facilities, which were geocoded in ArcGIS, were ascertained. Travel times from every census tract in the continental United States and Hawaii to the nearest parent and satellite facilities were calculated. Census-based population attributes were used to characterize measures of geographic access for sociodemographic groups. From the 62 NCI cancer centers providing clinical care in 2014, 76 unique parent locations and 211 satellite locations were mapped. The overall proportion of the population within 60 minutes of a facility was 22% for parent facilities and 32.7% for satellite facilities. When satellites were included for potential access, the proportion of some racial groups for which a satellite was the closest NCI cancer center facility increased notably (Native Americans, 22.6% with parent facilities and 39.7% with satellite facilities; whites, 34.8% with parent facilities and 50.3% with satellite facilities; and Asians, 40.0% with parent facilities and 54.0% with satellite facilities), with less marked increases for Hispanic and black populations. Rural populations of all categories had dramatically low proportions living within 60 minutes of an NCI cancer center facility of any type (1.0%-6.6%). Approximately 14% of the population (n = 43,033,310) lived more than 180 minutes from a parent or satellite facility, and most of these individuals were Native Americans and/or rural residents (37% of Native Americans and 41.7% of isolated rural residents). Racial/ethnic and rural populations showed markedly improved geographic access to NCI cancer center care when satellite facilities were included. Cancer 2017;123:3305-11. © 2017 American Cancer Society. © 2017 American

  4. The world's largest LNG producer's next market

    International Nuclear Information System (INIS)

    Fuller, R.; Isworo Suharno; Simandjuntak, W.M.P.

    1996-01-01

    The development of the domestic gas market in Indonesia, the world's largest liquefied natural gas producing country, is described as part of the overall impact of the country's oil and gas production. The first large scale use of natural gas in Indonesia was established in 1968 when a fertiliser plant using gas as the feedstock was built. Ultimately, through increased yields, this has enabled Indonesia to be self-sufficient in rice and an exporter of fertiliser. Problems which stand in the way of further developments include: capital, though Pertamina and PGN are perceived as attractive for foreign investment; the lack of a regulatory framework for gas; geographical constraints, among them the fact that the gas deposits are remote from the largest population concentrations; lack of infrastructure. There are nevertheless plans for expansion and the provision of an integrated gas pipeline system. Pertamina, which has responsibility for all oil and gas developments, and PGN, whose primary role has been as a manufacturer and distributor of gas, are now working together in the coordination of all gas activities. (10 figures). (UK)

  5. Sex expression and floral diversity in Jatropha curcas: a population study in its center of origin

    Science.gov (United States)

    Adriano-Anaya, María de Lourdes; Pérez-Castillo, Edilma; Salvador-Figueroa, Miguel; Ruiz-González, Sonia; Vázquez-Ovando, Alfredo; Grajales-Conesa, Julieta

    2016-01-01

    Sex expression and floral morphology studies are central to understand breeding behavior and to define the productive potential of plant genotypes. In particular, the new bioenergy crop Jatropha curcas L. has been classified as a monoecious species. Nonetheless, there is no information about its reproductive diversity in the Mesoamerican region, which is considered its center of origin and diversification. Thus, we determined sex expression and floral morphology in J. curcas populations from southern Mexico and Guatemala. Our results showed that most of J. curcas specimens had typical inflorescences with separate sexes (monoecious); meanwhile, the rest were atypical (gynoecious, androecious, andromonoecious, androgynomonoecious). The most important variables to group these populations, based on a discriminant analysis, were: male flower diameter, female petal length and male nectary length. From southern Mexico “Guerrero” was the most diverse population, and “Centro” had the highest variability among the populations from Chiapas. A cluster analysis showed that the accessions from southern Mexico were grouped without showing any correlation with the geographical origin, while those accessions with atypical sexuality were grouped together. To answer the question of how informative are floral morphological traits compared to molecular markers, we perform a Mantel correlation test between the distance matrix generated in this study and the genetic distance matrix (AFLP) previously reported for the same accessions. We found significant correlation between data at the level of accessions. Our results contribute to design genetic improvement programs by using sexually and morphologically contrasting plants from the center of origin. PMID:27257548

  6. Significance of population centers as sources of gaseous and dissolved PAHs in the lower Great Lakes.

    Science.gov (United States)

    McDonough, Carrie A; Khairy, Mohammed A; Muir, Derek C G; Lohmann, Rainer

    2014-07-15

    Polyethylene passive samplers (PEs) were used to measure concentrations of gaseous and dissolved polycyclic aromatic hydrocarbons (PAHs) in the air and water throughout the lower Great Lakes during summer and fall of 2011. Atmospheric Σ15PAH concentrations ranged from 2.1 ng/m3 in Cape Vincent (NY) to 76.4 ng/m3 in downtown Cleveland (OH). Aqueous Σ18PAH concentrations ranged from 2.4 ng/L at an offshore Lake Erie site to 30.4 ng/L in Sheffield Lake (OH). Gaseous PAH concentrations correlated strongly with population within 3-40 km of the sampling site depending on the compound considered, suggesting that urban centers are a primary source of gaseous PAHs (except retene) in the lower Great Lakes region. The significance of distant population (within 20 km) versus local population (within 3 km) increased with subcooled liquid vapor pressure. Most dissolved aqueous PAHs did not correlate significantly with population, nor were they consistently related to river discharge, wastewater effluents, or precipitation. Air-water exchange calculations implied that diffusive exchange was a source of phenanthrene to surface waters, while acenaphthylene volatilized out of the lakes. Comparison of air-water fluxes with temperature suggested that the significance of urban centers as sources of dissolved PAHs via diffusive exchange may decrease in warmer months.

  7. Loy Yang A - Australia's largest privatisation

    International Nuclear Information System (INIS)

    Yenckin, C.

    1997-01-01

    The recent A$4,746 million privatisation of the 2000MW Loy Yang A power station and the Loy Yang coal mine by the Victorian Government is Australia's largest privatisation and one of 1997's largest project financing deals. (author)

  8. Lessons learned obtaining informed consent in research with vulnerable populations in community health center settings

    Directory of Open Access Journals (Sweden)

    Riden Heather E

    2012-11-01

    Full Text Available Abstract Background To improve equity in access to medical research, successful strategies are needed to recruit diverse populations. Here, we examine experiences of community health center (CHC staff who guided an informed consent process to overcome recruitment barriers in a medical record review study. Methods We conducted ten semi-structured interviews with CHC staff members. Interviews were audiotaped, transcribed, and structurally and thematically coded. We used NVivo, an ethnographic data management software program, to analyze themes related to recruitment challenges. Results CHC interviewees reported that a key challenge to recruitment included the difficult balance between institutional review board (IRB requirements for informed consent, and conveying an appropriate level of risk to patients. CHC staff perceived that the requirements of IRB certification itself posed a barrier to allowing diverse staff to participate in recruitment efforts. A key barrier to recruitment also included the lack of updated contact information on CHC patients. CHC interviewees reported that the successes they experienced reflected an alignment between study aims and CHC goals, and trusted relationships between CHCs and staff and the patients they recruited. Conclusions Making IRB training more accessible to CHC-based staff, improving consent form clarity for participants, and developing processes for routinely updating patient information would greatly lower recruitment barriers for diverse populations in health services research.

  9. broken magnet highlights largest collider's engineering challenges

    CERN Multimedia

    Inman, Mason

    2007-01-01

    "Even at the world's soon-to-be largest particle accelerator - a device that promises to push the boundaries of physics - scientists need to be mindful of one of the most fundamental laws in the universe: Murphy's Law. (2 pages)

  10. Radiotelemetry Study of a Desert Tortoise Population: Sand Hill Training Mea, Marine Corps Air Ground Combat Center, Twentynine Palms, California

    Science.gov (United States)

    1998-05-01

    shallow caliche burrows. Mojave populations differ genetically ( Lamb et al. 1989), morphologically (Weinstein and Berry 1987), in burrow construction...34 Abstract in The Desert Tortoise Council Symposium (1995d), p 92. Lamb , T., J.C. Avise, and J.W. Gibbons, "Phylogeographic Patterns in Mitochondrial...ATTN: STEWS -EL US Army Envr Hygiene Agency ATTN:HSHB-ME 21010 US Army Environmental Center ATTN: SFIM-AEC 21010-5401 Defense Tech Info Center

  11. One of the largest obstacles to understanding the population ...

    African Journals Online (AJOL)

    spamer

    larvae is a lack of knowledge of the mechanisms by which larvae ... temperature change, is critical to interannual settlement variability. The average ... of planktonic larvae relative to a nearshore retention feature is dependent on taxon.

  12. Academic medical centers as innovation ecosystems to address population -omics challenges in precision medicine.

    Science.gov (United States)

    Silva, Patrick J; Schaibley, Valerie M; Ramos, Kenneth S

    2018-02-15

    While the promise of the Human Genome Project provided significant insights into the structure of the human genome, the complexities of disease at the individual level have made it difficult to utilize -omic information in clinical decision making. Some of the existing constraints have been minimized by technological advancements that have reduced the cost of sequencing to a rate far in excess of Moore's Law (a halving in cost per unit output every 18 months). The reduction in sequencing costs has made it economically feasible to create large data commons capturing the diversity of disease across populations. Until recently, these data have primarily been consumed in clinical research, but now increasingly being considered in clinical decision- making. Such advances are disrupting common diagnostic business models around which academic medical centers (AMCs) and molecular diagnostic companies have collaborated over the last decade. Proprietary biomarkers and patents on proprietary diagnostic content are no longer driving biomarker collaborations between industry and AMCs. Increasingly the scope of the data commons and biorepositories that AMCs can assemble through a nexus of academic and pharma collaborations is driving a virtuous cycle of precision medicine capabilities that make an AMC relevant and highly competitive. A rebalancing of proprietary strategies and open innovation strategies is warranted to enable institutional precision medicine asset portfolios. The scope of the AMC's clinical trial and research collaboration portfolios with industry are increasingly dependent on the currency of data, and less on patents. Intrapeneurial support of internal service offerings, clinical trials and clinical laboratory services for example, will be important new points of emphasis at the academic-industry interface. Streamlining these new models of industry collaboration for AMCs are a new area for technology transfer offices to offer partnerships and to add value

  13. CERN tests largest superconducting solenoid magnet

    CERN Multimedia

    2006-01-01

    "CERN's Compacts Muon Solenoid (CMS) - the world's largest superconducting solenoid magnet - has reached full field in testing. The instrument is part of the proton-proton Large Hadron Collider (LHC) project, located in a giant subterranean chamber at Cessy on the Franco-Swiss border." (1 page)

  14. New Chicago-Indiana computer network will handle dataflow from world's largest scientific experiment

    CERN Multimedia

    2006-01-01

    "Massive quantities of data will soon begin flowing from the largest scientific instrument ever built into an international netword of computer centers, including one operated jointly by the University of Chicago and Indiana University." (1,5 page)

  15. Dynamics of Race, Culture and Key Indicators of Health In the Nations 100 Largest Cities and Their Suburbs. The Social and Health Landscape of Urban and Suburban America Report Series.

    Science.gov (United States)

    Andrulis, Dennis P.; Duchon, Lisa M.; Reidj, Hailey M.

    This report profiles the 2000 status of and changes (since 1990) in rates of health and health-related measures for racially and culturally diverse populations living in the 100 largest U.S. cities and their suburbs. Data came from the U.S. Census Bureau and Centers for Disease Control and Prevention to identify patterns in race/ethnicity, foreign…

  16. Community centers of UNESCO-Chernobyl programme-psychological support model for population in a post-catastrophe crisis

    Energy Technology Data Exchange (ETDEWEB)

    Garnets, O. [UNESCO-Chernobyl Programme Project (Ukraine)

    1998-07-01

    Community Centers for Psycho-social Rehabilitation created within UNESCO - Chernobyl Programme (Project no 64) is aimed at providing psychological support to population suffered from the catastrophe. Centers are located in communities that in different ways suffered from Chernobyl - people evacuated and relocated from the contaminated territories, people who are still living in contaminated regions, employees of the nuclear power plant etc. Centres are providing psychological support to people suffered from Chernobyl catastrophe, trough developing adaptive behavior models under living conditions that changed - both ecological and social and economic crises, developing of personal and social responsibility in community members. The professionals of Community Centers implement activities aimed on coping victimization, on community interaction and communities restructuring. They are working with all age and social groups in the communities, with acute crises and suicide prevention, creating mutual support mechanisms. Centres performance results in decrease of psycho-social tension and anxiety in population. Centers present successfully functioning model of social and psychological support under complicated ecological and social conditions in post soviet countries. They have accumulated unique professional and organizational experience of efficient work in, a post-catastrophe period under social and economic crisis. (author)

  17. Community centers of UNESCO-Chernobyl programme-psychological support model for population in a post-catastrophe crisis

    International Nuclear Information System (INIS)

    Garnets, O.

    1998-01-01

    Community Centers for Psycho-social Rehabilitation created within UNESCO - Chernobyl Programme (Project no 64) is aimed at providing psychological support to population suffered from the catastrophe. Centers are located in communities that in different ways suffered from Chernobyl - people evacuated and relocated from the contaminated territories, people who are still living in contaminated regions, employees of the nuclear power plant etc. Centres are providing psychological support to people suffered from Chernobyl catastrophe, trough developing adaptive behavior models under living conditions that changed - both ecological and social and economic crises, developing of personal and social responsibility in community members. The professionals of Community Centers implement activities aimed on coping victimization, on community interaction and communities restructuring. They are working with all age and social groups in the communities, with acute crises and suicide prevention, creating mutual support mechanisms. Centres performance results in decrease of psycho-social tension and anxiety in population. Centers present successfully functioning model of social and psychological support under complicated ecological and social conditions in post soviet countries. They have accumulated unique professional and organizational experience of efficient work in, a post-catastrophe period under social and economic crisis. (author)

  18. Crash testing the largest experiment on Earth

    OpenAIRE

    Cauchi, Marija

    2015-01-01

    Under Europe lies a 27 km tunnel that is both the coldest and hottest place on Earth. The Large Hadron Collider (LHC) has already found out what gives mass to all the matter in the Universe. It is now trying to go even deeper into what makes up everything we see around us. Dr Marija Cauchi writes about her research that helped protect this atom smasher from itself. Photography by Jean Claude Vancell. http://www.um.edu.mt/think/crash-testing-the-largest-experiment-on-earth/

  19. BALU: Largest autoclave research facility in the world

    Directory of Open Access Journals (Sweden)

    Hakan Ucan

    2016-03-01

    Full Text Available Among the large-scale facilities operated at the Center for Lightweight-Production-Technology of the German Aerospace Center in Stade BALU is the world's largest research autoclave. With a loading length of 20m and a loading diameter of 5.8 m the main objective of the facility is the optimization of the curing process operated by components made of carbon fiber on an industrial scale. For this reason, a novel dynamic autoclaving control has been developed that is characterized by peripheral devices to expend the performance of the facility for differential applications, by sensing systems to detect the component state throughout the curing process and by a feedback system, which is capable to intervene into the running autoclave process.

  20. About Skin: Your Body's Largest Organ

    Science.gov (United States)

    ... Registration General information Housing & travel Education Exhibit hall Mobile app 2019 Annual Meeting Derm Exam Prep Course ... SkinPAC State societies Scope of practice Truth in advertising NP/PA laws Action center Public and patients ...

  1. Creating 21st-Century Laboratories and Classrooms for Improving Population Health: A Call to Action for Academic Medical Centers.

    Science.gov (United States)

    DeVoe, Jennifer E; Likumahuwa-Ackman, Sonja; Shannon, Jackilen; Steiner Hayward, Elizabeth

    2017-04-01

    Academic medical centers (AMCs) in the United States built world-class infrastructure to successfully combat disease in the 20th century, which is inadequate for the complexity of sustaining and improving population health. AMCs must now build first-rate 21st-century infrastructure to connect combating disease and promoting health. This infrastructure must acknowledge the bio-psycho-social-environmental factors impacting health and will need to reach far beyond the AMC walls to foster community "laboratories" that support the "science of health," complementary to those supporting the "science of medicine"; cultivate community "classrooms" to stimulate learning and discovery in the places where people live, work, and play; and strengthen bridges between academic centers and these community laboratories and classrooms to facilitate bidirectional teaching, learning, innovation, and discovery.Private and public entities made deep financial investments that contributed to the AMC disease-centered approach to clinical care, education, and research in the 20th century. Many of these same funders now recognize the need to transform U.S. health care into a system that is accountable for population health and the need for a medical workforce equipped with the skills to measure and improve health. Innovative ideas about communities as centers of learning, the importance of social factors as major determinants of health, and the need for multidisciplinary perspectives to solve complex problems are not new; many are 20th-century ideas still waiting to be fully implemented. The window of opportunity is now. The authors articulate how AMCs must take bigger and bolder steps to become leaders in population health.

  2. Vaginismus in Assisted Reproductive Technology Centers: an invisible population in need of care.

    Science.gov (United States)

    Souza, Maria do Carmo B de; Gusmão, Marcia C G; Antunes, Roberto A; Souza, Marcelo M de; Rito, Ana L S; Lira, Paloma; Mancebo, Ana C A; Tamm, Maria A; Panaino, Tatiana R; Bahia, Maria J

    2018-03-01

    Genital and sexual pain is still neglected. Consequences may be dramatic, since infertility and sexual dysfunction may be reciprocally linked. This is the first study to focus on the identification of cases of vaginismus in the ART scenario and on the introduction of intra-cycle interventions as part of a comprehensive, integrated and patient-centered perspective. This observational prospective study looked into 425 IVF/ICSI cycles and 226 frozen embryo transfers carried out from January 1, 2015 to December 31, 2016, and found seven cases of vaginismus. Within a six-month period, a questionnaire placed on SurveyMonkey was sent twice to 228 ART centers in Latin America. The purpose was to learn how often cases of vaginismus were found in ART centers and the perceptions around the presence of this condition. The few centers that took the time to answer the questionnaire (24/10.5%) stated that the number of cases in which they had trouble performing control ultrasound examination or needed to perform transfers with patients under sedation was not significant. Although 81% agreed that the incidence of these conditions is low, no references were made to cases of vaginismus, dyspareunia or sexual dysfunction. Our multidisciplinary team found seven cases of vaginismus, involving women with higher education degrees with a mean age of 37.8 years and married for a mean of four years. Although two reported they were able to tolerate intercourse, all reported undergoing treatments such as using vaginal dilators (3), psychotherapy (4) and psychiatric care (1). The care provided by the staff was designed to mitigate patient suffering. Gentle care and sensitive listening should be integral components in the work of multidisciplinary teams to identify women with vaginismus and offer couples better quality treatment.

  3. Perceptions of Smartphone User-Centered Mobile Health Tracking Apps Across Various Chronic Illness Populations: An Integrative Review.

    Science.gov (United States)

    Birkhoff, Susan D; Smeltzer, Suzanne C

    2017-07-01

    This integrative review presents a synthesis of the current qualitative research addressing the motivating factors, usability, and experiences of mobile health tracking applications (apps) across various chronic disease populations. Integrative review of the literature. Databases used to conduct this integrative review included: PubMed Plus, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Google Scholar, Science Direct, and EBSCO megafile. The following search terms were used in all five databases: smartphone apps, apps, mHealth, eHealth, mobile health apps, health tracking apps, user-centered apps, wireless technology, engagement, qualitative, and usability. The initial literature review yielded 689 results. Once inclusion and exclusion criteria were employed, 11 studies met the criteria set forth for this review. The reviewed studies provided insight into users' perceptions, experiences, and motivations to incorporate smartphone mobile health apps into their daily lives when living with chronic illnesses. This review indicates the growing interest in user-centered mobile health tracking apps, but with little understanding of motivating factors that foster sustained app use. Mobile health tracking apps targeted to users with chronic conditions need to have a high level of usability in order to motivate users to sustain engagement with their mobile health tracking app. User-centered mobile health tracking app technology is being used with increasing frequency to potentially provide individualized support to chronic illness populations. © 2017 Sigma Theta Tau International.

  4. Gender and smoking-related risk of lung cancer. The Copenhagen Center for Prospective Population Studies

    DEFF Research Database (Denmark)

    Prescott, E; Osler, M; Hein, H O

    1998-01-01

    Our aim was to compare risk of lung cancer associated with smoking by gender and histologic type. A total of 30,874 subjects, 44% women, from three prospective population-based studies with initial examinations between 1964 and 1992 were followed until 1994 through the National Cancer Registry...

  5. Health Self-Efficacy Among Populations with Multiple Chronic Conditions: the Value of Patient-Centered Communication.

    Science.gov (United States)

    Finney Rutten, Lila J; Hesse, Bradford W; St Sauver, Jennifer L; Wilson, Patrick; Chawla, Neetu; Hartigan, Danielle B; Moser, Richard P; Taplin, Stephen; Glasgow, Russell; Arora, Neeraj K

    2016-08-01

    Using cross-sectional survey data, we assessed the association between chronic illness burden and health-related self-efficacy, evaluating whether patient-centered communication is associated with self-efficacy and if that relationship varies by chronic illness burden. Data were from the Health Information National Trends Survey, a cross-sectional survey of the US adult population collected in 2012-2013 (n = 3630). Health-related self-efficacy was measured with the item: "Overall, how confident are you about your ability to take good care of your health?" and the prevalence of six chronic conditions and depression/anxiety was assessed. Patient-centered communication was measured as the frequency with which respondents perceived their healthcare providers allowed them to ask questions, gave attention to their emotions, involved them in decisions, made sure they understood how to take care of their health, helped them to deal with uncertainty, and if they felt they could rely on their healthcare providers to take care of their healthcare needs. Health-related self-efficacy was significantly lower among individuals with greater illness burden. In adjusted analysis, individuals who experienced more positive patient-centered communication reported higher levels of self-efficacy (β = 0.26, P self-efficacy were observed among patients reporting more positive patient-centered communication; the observed association was stronger among those with greater chronic illness burden.

  6. Neuropathy in the hemodialysis population: a review of neurophysiology referrals in a tertiary center.

    LENUS (Irish Health Repository)

    O'Regan, John

    2012-01-01

    This was a retrospective observational study of neurophysiology referrals over 8 years from a tertiary referral center in Ireland. A total of 68 of the 73 referrals yielded one or more abnormalities. Thirty-nine (53%) patients had one or more mononeuropathies; iatrogenic mononeuropathies believed to be associated with arterio-venous fistula creation occurred in 15 patients. Polyneuropathy was identified in 43 patients (59%). Access to an experienced neurophysiology department offers valuable insight into dialysis-associated neuropathies, especially when associated with arterio-venous fistulae.

  7. Identifying elements of patient-centered care in underserved populations: a qualitative study of patient perspectives.

    Directory of Open Access Journals (Sweden)

    Sheela Raja

    Full Text Available Patient-centered care is an important goal in the delivery of healthcare. However, many patients do not engage in preventive medical care. In this pilot study, we conducted twenty in depth, semi-structured qualitative interviews at the University of Illinois at Chicago Health Sciences campus in a four month time frame. Many patients were underserved and underinsured, and we wanted to understand their experiences in the healthcare system. Using content analysis, several themes emerged from the interview data. Participants discussed the need for empathy and rapport with their providers. They identified provider behaviors that fostered a positive clinical relationship, including step-by step explanations of procedures, attention to body language and clinic atmosphere, and appropriate time management. Participants identified cost as the most common barrier to engaging in preventive care and discussed children and social support as motivating factors. A long-term relationship with a provider was an important motivator for preventive care, suggesting that the therapeutic alliance was essential to many patients. Conversely, many participants discussed a sense of dehumanization in the healthcare system, reporting that their life circumstances were overlooked, or that they were judged based on insurance status or ethnicity. We discuss implications for provider training and healthcare delivery, including the importance of patient-centered medical homes.

  8. Generalized Population Analysis of Three-Center Two-Electron Bonding

    Czech Academy of Sciences Publication Activity Database

    Ponec, Robert; Cooper, D. L.

    2004-01-01

    Roč. 97, č. 6 (2004), s. 1002-1011 ISSN 0020-7608 R&D Projects: GA AV ČR IAA4072006; GA MŠk OC D9.20 Institutional research plan: CEZ:AV0Z4072921 Keywords : multicenter bonding * generalized population analysis * post-Hartree Fock wave functions Subject RIV: CF - Physical ; The oretical Chemistry Impact factor: 1.392, year: 2004

  9. Evolution of the Largest Mammalian Genome.

    Science.gov (United States)

    Evans, Ben J; Upham, Nathan S; Golding, Goeffrey B; Ojeda, Ricardo A; Ojeda, Agustina A

    2017-06-01

    The genome of the red vizcacha rat (Rodentia, Octodontidae, Tympanoctomys barrerae) is the largest of all mammals, and about double the size of their close relative, the mountain vizcacha rat Octomys mimax, even though the lineages that gave rise to these species diverged from each other only about 5 Ma. The mechanism for this rapid genome expansion is controversial, and hypothesized to be a consequence of whole genome duplication or accumulation of repetitive elements. To test these alternative but nonexclusive hypotheses, we gathered and evaluated evidence from whole transcriptome and whole genome sequences of T. barrerae and O. mimax. We recovered support for genome expansion due to accumulation of a diverse assemblage of repetitive elements, which represent about one half and one fifth of the genomes of T. barrerae and O. mimax, respectively, but we found no strong signal of whole genome duplication. In both species, repetitive sequences were rare in transcribed regions as compared with the rest of the genome, and mostly had no close match to annotated repetitive sequences from other rodents. These findings raise new questions about the genomic dynamics of these repetitive elements, their connection to widespread chromosomal fissions that occurred in the T. barrerae ancestor, and their fitness effects-including during the evolution of hypersaline dietary tolerance in T. barrerae. ©The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  10. Large Population-Based Study Reveals Disparities in Myeloma Precursor Disease | Center for Cancer Research

    Science.gov (United States)

    Multiple myeloma (MM) is a cancer of plasma cells, which are antibody-producing white blood cells. Patients with MM have a characteristic excess of monoclonal antibodies, so called M proteins, in their serum, urine, or both and plasma cell infiltration into their bone marrow at multiple sites. African Americans are more than twice as likely as whites to develop MM, but the reason for this higher prevalence is not entirely clear. Since MM is nearly always preceded by the premalignant condition monoclonal gammopathy of undetermined significance (MGUS), Ola Landgren, M.D., Ph.D., a Senior Investigator in CCR’s Lymphoid Malignancies Branch, and colleagues from NCI’s Division of Cancer Epidemiology and Genetics, the Mayo Clinic, and the Centers for Disease Control and Prevention (CDC), wanted to determine whether there were also disparities in MGUS prevalence or in biomarkers associated with a high risk of MGUS progression to MM.

  11. Canada's largest co-gen project

    International Nuclear Information System (INIS)

    Salaff, S.

    2000-01-01

    In November 2000, the TransAlta Energy Corp. began construction on its $400 million natural gas fuelled cogeneration project in Sarnia Ontario. The Sarnia Regional Cogeneration Project (SRCP) is designed to integrate a new 440 MW cogeneration facility to be built at the Sarnia Division of Dow Chemicals Canada Inc. with nearby existing generators totaling 210 MW at Dow and Bayer Inc. At 650 MW, the new facility will rank as Canada's largest cogeneration installation. Commercial operation is scheduled for October 2002. TransAlta owns three natural gas fuelled cogeneration facilities in Ontario (in Ottawa, Mississauga and Windsor) totaling 250 MW. The cost of electric power in Ontario is currently controlled by rising natural gas prices and the supply demand imbalance. This balance will be significantly affected by the possible return to service of 2000 MW of nuclear generating capacity. The SRCP project was announced just prior to the Ontario Energy Competition Act of October 1998 which committed the province to introduce competition to the electricity sector and which created major uncertainties in the electricity market. Some of the small, 25 MW projects which survived the market uncertainty included the Toronto-based Toromont Energy Ltd. project involving gas fuelled cogeneration and methane gas generation from landfill projects in Sudbury and Waterloo. It was emphasized that cogeneration and combined heat and power projects have significant environmental advantages over large combined cycle facilities. The Ontario Energy Board is currently considering an application from TransAlta to link the SRCP facility to Ontario's Hydro One Network Inc.'s transmission grid. 1 fig

  12. Patient-centered medical homes in Louisiana had minimal impact on Medicaid population's use of acute care and costs.

    Science.gov (United States)

    Cole, Evan S; Campbell, Claudia; Diana, Mark L; Webber, Larry; Culbertson, Richard

    2015-01-01

    The patient-centered medical home model of primary care has received considerable attention for its potential to improve outcomes and reduce health care costs. Yet little information exists about the model's ability to achieve these goals for Medicaid patients. We sought to evaluate the effect of patient-centered medical home certification of Louisiana primary care clinics on the quality and cost of care over time for a Medicaid population. We used a quasi-experimental pre-post design with a matched control group to assess the effect of medical home certification on outcomes. We found no impact on acute care use and modest support for reduced costs and primary care use among medical homes serving higher proportions of chronically ill patients. These findings provide preliminary results related to the ability of the patient-centered medical home model to improve outcomes for Medicaid beneficiaries. The findings support a case-mix-adjusted payment policy for medical homes going forward. Project HOPE—The People-to-People Health Foundation, Inc.

  13. [Evaluation of the population received and cared for in France in the "Doctors of the World" Health Centers].

    Science.gov (United States)

    Moncorgé, C; Picard, H

    1997-11-01

    For 11 years now, Médecins du Monde's Mission to France has tried to respond to the needs of a part of marginalized population, which has no access to health care. In 1996, 72,000 consultations have been given throughout the 31 free Health centers based in 31 cities in France. Who is this population? Basically young people (more than half are under the age of 30 and 10% are underaged), men in 213 of the cases, living alone, in 80% of the cases. How do they live? Almost 65% live with less than 20 francs per day (given by social care); 54% are officially jobless. As far as housing is concerned, only 1/4 have a home (women in particular). The others live in hostels, self-made shelters, hotels, or with relatives; 13% admit living on the street. Why do they come to health centers? Almost all diseases observed are identical to the ones detected in regular Health care centers, i.e., Ear--Nose and Throat, respiratory and gynecological infections. What makes them particular is the fact they are diagnosed later than usual, which makes them more serious than usual. The living conditions of this marginalized population explain the high frequency of skin problems (12%) and neuropsychologic disorders. Why do they come to Médecins du Monde? 1/4 of the patients do benefit from social welfare, but are unable to advance the payment of medical costs, or support the difference between the actual cost and the reimbursement by the Social security. 40% have no social coverage whatsoever. However, other motives (1 to 7%) such as administrative problems, rights outside their district, refusal to start the administrative procedures, ignorance of their rights ... are rarely put forward. The population with no access to health care is still unknown. This is why the information gathered is so important. It allows a better qualification of the patients' requests and, consequently, a better comprehension of the social exclusion phenomenon, particularly in the area of health.

  14. Fishing down the largest coral reef fish species.

    Science.gov (United States)

    Fenner, Douglas

    2014-07-15

    Studies on remote, uninhabited, near-pristine reefs have revealed surprisingly large populations of large reef fish. Locations such as the northwestern Hawaiian Islands, northern Marianas Islands, Line Islands, U.S. remote Pacific Islands, Cocos-Keeling Atoll and Chagos archipelago have much higher reef fish biomass than islands and reefs near people. Much of the high biomass of most remote reef fish communities lies in the largest species, such as sharks, bumphead parrots, giant trevally, and humphead wrasse. Some, such as sharks and giant trevally, are apex predators, but others such as bumphead parrots and humphead wrasse, are not. At many locations, decreases in large reef fish species have been attributed to fishing. Fishing is well known to remove the largest fish first, and a quantitative measure of vulnerability to fishing indicates that large reef fish species are much more vulnerable to fishing than small fish. The removal of large reef fish by fishing parallels the extinction of terrestrial megafauna by early humans. However large reef fish have great value for various ecological roles and for reef tourism. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Possible limitations to SSPS use due to distribution of world population and world energy consumption centers

    Energy Technology Data Exchange (ETDEWEB)

    Claverie, M.J.; Dupas, A.P.

    1980-09-01

    Satellite solar power stations, as envisioned now, would be very large energy systems from the point of view of power output (about 5 GW) and of land requirements (more than 400 sq km for a rectenna and the associated exclusion area). These size constraints could lead to limitations in the use of SSPS in significant parts of the world, due to three main incompatibilities: too high population density, insufficient density of electrical demand, and obligation for a single power station to provide less than about 20% of the total electrical demand in a given geographical zone to assure reliability. The extent of these three possible limitations was assessed, using a future world energy model developed previously. The rationale behind this model is to divide the world into 10 deg latitude by 10 deg longitude zones, in which future electrical demands (in 2000 and 2020/2025) are computed according to energetical previsions of the Case Western Reserve University (CWRU) and of the World Energy Conference (WEC). The results are world wide maps of electrical demand densities in 2000 and 2020/2025.

  16. Bariatric Surgery to Target Obesity in the Renal Transplant Population: Preliminary Experience in a Single Center.

    Science.gov (United States)

    Gazzetta, P G; Bissolati, M; Saibene, A; Ghidini, C G A; Guarneri, G; Giannone, F; Adamenko, O; Secchi, A; Rosati, R; Socci, C

    2017-05-01

    During the last century, obesity has become a global epidemic. The effect of obesity on renal transplantation may occur in perioperative complications and impairment of organ function. Obese patients have metabolic derangements that can be exacerbated after transplantation and obesity directly impacts most transplantation outcomes. These recipients are more likely to develop adverse graft events, such as delayed graft function and early graft loss. Furthermore, obesity is synergic to some immunosuppressive agents in triggering diabetes and hypertension. As behavioral weight loss programs show disappointing results in these patients, bariatric surgery has been considered as a means to achieve rapid and long-term weight loss. Up-to-date literature shows laparoscopic bariatric surgery is feasible and safe in transplantation candidates and increases the rate of transplantation eligibility in obese patients with end-stage organ disease. There is no evidence that restrictive procedures modify the absorption of immunosuppressive medications. From 2013 to 2016 we performed six bariatric procedures (sleeve gastrectomy) on obese patients with renal transplantation; mean preoperative body mass index (BMI) was 39.8 kg/m 2 . No postoperative complication was observed and no change in the immunosuppressive medications regimen was needed. Mean observed estimated weight loss was 27.6%, 44.1%, 74.2%, and 75.9% at 1, 3, 6, and 12 months follow-up, respectively. Our recommendation is to consider patients with BMI >30 kg/m 2 as temporarily ineligible for transplantation and as candidates to bariatric surgery if BMI >35 kg/m 2 . We consider laparoscopic sleeve gastrectomy as a feasible, first-choice procedure in this specific population. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Access to Grafts in a Liver Transplant Center: Does It Rely on the Severity of the Waiting List Population?

    Science.gov (United States)

    Daciuk, N I; Quiñonez, E G; Poupard, M; Vergara Sandoval, R M; Mattera, F J

    2018-03-01

    The number of transplants performed relies, partially, on recipients' variables on the waiting list. The goal of this study was to compare recipients from a high-volume liver center in Argentina with the rest of the country. This study was a retrospective analysis of liver transplant recipients nationally between January 2013 and April 2017. It involved extracting data from the open database CRESI-SINTRA (the Argentinian database of the National Procurement Organization, an equivalent to the United Network for Organ Sharing); expressing results by percentages, medians, and interquartile ranges (IQRs); and comparing the national population with the population transplanted at Hospital El Cruce (HEC). The Mann-Whitney U test was used for analysis. Nationally, 1434 liver transplants were performed. A total of 177 (12.34%) were emergency status; 811 (56.6%) were by the Model for End-Stage Liver Disease (MELD) (n = 759)/PELD (Pediatric End-Stage Liver Disease) (n = 52), with a median graft assignment position of 5 (IQR, 3-10) in 57.2 days (IQR, 11-217). Median MELD access was 29 points (IQR, 24-33). A total of 446 (31.1%) had MELD exceptions; 249 (55.8%) of these were due to Milan hepatocellular carcinoma. At the HEC, 167 liver transplantations were performed; 26 (15.6%) were emergency status and 97 (58.1%) by MELD (none PELD). Their median graft assignment position was 4 (IQR, 4-16) in 19.1 days (IQR, 4-90); median MELD access was 28 points (IQR, 24-31). Forty-five patients (26.9%) had MELD exceptions; 31 (68.9%) were due to hepatocellular carcinoma. Our center has a larger proportion of recipients transplanted by emergency status and MELD, similar MELD access, and less waiting list time, reflecting our wide policy of liver graft acceptance. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Pattern of glomerular disease in the Saudi population: A single-center, five-year retrospective study

    Directory of Open Access Journals (Sweden)

    Z Nawaz

    2013-01-01

    Full Text Available Glomerular diseases continue to be the leading cause of end-stage renal disease (ESRD globally. Hence, it is important to recognize the pattern of glomerular diseases in different geographical areas in order to understand the patho-biology, incidence and progression of the disorder. Published studies from different centers in Saudi Arabia have reported contradicting results. In this retrospective study, we report our experience at the Armed Forces Hospital, Riyadh, Saudi Arabia. A total of 348 native renal biopsies performed at our center on patients with proteinuria >1 g, hematuria and/or renal impairment during a period of 5 years (between January 2005 and December 2009 were studied by a histopathologist using light microscopy, immunofluorescence and electron microscopy, and were categorized. Results showed that primary glomerular disease accounted for 55.1% of all renal biopsies. The most common histological lesion was focal and segmental glomerulosclerosis (FSGS (27.6%, followed by minimal change disease (MCD (17.7% and membrano-proliferative glomerulonephritis (MPGN (13.0%. Secondary glomerular disease accounted for 37.9% of the glomerular diseases, with lupus nephritis (LN being the most common lesion (54.5%, followed by hypertensive nephrosclerosis (22%, post-infectious glomerulonephritis (7.5%, diabetic nephropathy (DN (6.8% and vasculitides (4.5%. Four percent of all biopsies turned out to be ESRD while biopsy was inadequate in 2.8% of the cases. In conclusion, our study showed that FSGS was the most common primary GN encountered, while LN was the most common secondary GN. We encountered 14 cases of crescentic glomerulonephritis. Also, the prevalence of MPGN, MCD, IgA nephropathy and membranous GN was many folds higher in males when compared with the Western data. We believe that it is mandatory to maintain a Saudi Arabian Renal Biopsy Registry to understand better the pattern of glomerular disease in the Saudi population and to follow

  19. Changes in Enterococcal and E coli populations and related antibiotic resistance from medical center to receiving environment

    Science.gov (United States)

    Petit, F.; Berthe, T.; Oberle, K.; Denamur, E.; Clermont, O.; Leclercq, R.; Cattoir, V.; Budzinski, H.

    2013-12-01

    The spread of antibiotic-resistant faecal bacteria and their corresponding genes in water environment, as a result of the overuse of antibiotics, have become an ecological and a public problem. The aim of this multidisciplinary research program (FLASH) -associating chemists, hydrologists, clinical and environmental microbiologists- was to determine to what extent the hospital effluent have an ecological impact on the downstream aquatic environment. For this purpose, fate of Escherichia coli (distribution of phylogenetic groups, antibiotic resistance, integrons- 342 strains) and Enterococci (diversity, antibiotic resistance, genes ermB, mefA, clonal complex 17- 235 strains ) was analyzed in water and sediments along a medical center - WWTP - river - estuary continuum, during a high epidemiologic period in the North west of France. A multi-residue chemical methodology was developed in order to detect low levels of 34 antibiotics in water. To link occurrence of antibiotic-resistant bacteria in water and antibiotic prescription, we use the data collection from the hospital and the antibiotics sales information. In the medical center, the main prescribed antibiotic (amoxicillin) was weakly found in effluents. Along the continuum, contamination of water by antibiotics decreased from 160μg.L-1 (cefotaxim) in hospital effluents to 1ng.L-1 (ofloxacin) in the river. These concentrations were too low to exert a selective pressure (mg.L-1) on antibiotic-resistant bacteria. In same samples, occurrences of antibiotic-resistant E. coli and those harboring a class 1 integrons decreased significantly (p-value E. coli isolates, multiresistant to antibiotic, was observed in water microcosm experiment (E. coli and the corresponding antibiotic-resistance genes are submitted to the particle dynamics and are deposited on mudflats. Among Enterococcus populations, E. faecium was mainly isolated (from 89% to 98%). All E. faecium isolates from medical center effluents were multiply

  20. Benchmark Testing of the Largest Titanium Aluminide Sheet Subelement Conducted

    Science.gov (United States)

    Bartolotta, Paul A.; Krause, David L.

    2000-01-01

    To evaluate wrought titanium aluminide (gamma TiAl) as a viable candidate material for the High-Speed Civil Transport (HSCT) exhaust nozzle, an international team led by the NASA Glenn Research Center at Lewis Field successfully fabricated and tested the largest gamma TiAl sheet structure ever manufactured. The gamma TiAl sheet structure, a 56-percent subscale divergent flap subelement, was fabricated for benchmark testing in three-point bending. Overall, the subelement was 84-cm (33-in.) long by 13-cm (5-in.) wide by 8-cm (3-in.) deep. Incorporated into the subelement were features that might be used in the fabrication of a full-scale divergent flap. These features include the use of: (1) gamma TiAl shear clips to join together sections of corrugations, (2) multiple gamma TiAl face sheets, (3) double hot-formed gamma TiAl corrugations, and (4) brazed joints. The structural integrity of the gamma TiAl sheet subelement was evaluated by conducting a room-temperature three-point static bend test.

  1. Defining the Risk of Zika and Chikungunya Virus Transmission in Human Population Centers of the Eastern United States.

    Directory of Open Access Journals (Sweden)

    Carrie A Manore

    2017-01-01

    Full Text Available The recent spread of mosquito-transmitted viruses and associated disease to the Americas motivates a new, data-driven evaluation of risk in temperate population centers. Temperate regions are generally expected to pose low risk for significant mosquito-borne disease; however, the spread of the Asian tiger mosquito (Aedes albopictus across densely populated urban areas has established a new landscape of risk. We use a model informed by field data to assess the conditions likely to facilitate local transmission of chikungunya and Zika viruses from an infected traveler to Ae. albopictus and then to other humans in USA cities with variable human densities and seasonality. Mosquito-borne disease occurs when specific combinations of conditions maximize virus-to-mosquito and mosquito-to-human contact rates. We develop a mathematical model that captures the epidemiology and is informed by current data on vector ecology from urban sites. The model demonstrates that under specific but realistic conditions, fifty-percent of introductions by infectious travelers to a high human, high mosquito density city could initiate local transmission and 10% of the introductions could result in 100 or more people infected. Despite the propensity for Ae. albopictus to bite non-human vertebrates, we also demonstrate that local virus transmission and human outbreaks may occur when vectors feed from humans even just 40% of the time. Inclusion of human behavioral changes and mitigations were not incorporated into the models and would likely reduce predicted infections. This work demonstrates how a conditional series of non-average events can result in local arbovirus transmission and outbreaks of human disease, even in temperate cities.

  2. Population-centered Risk- and Evidence-based Dental Interprofessional Care Team (PREDICT): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Cunha-Cruz, Joana; Milgrom, Peter; Shirtcliff, R Michael; Bailit, Howard L; Huebner, Colleen E; Conrad, Douglas; Ludwig, Sharity; Mitchell, Melissa; Dysert, Jeanne; Allen, Gary; Scott, JoAnna; Mancl, Lloyd

    2015-06-20

    To improve the oral health of low-income children, innovations in dental delivery systems are needed, including community-based care, the use of expanded duty auxiliary dental personnel, capitation payments, and global budgets. This paper describes the protocol for PREDICT (Population-centered Risk- and Evidence-based Dental Interprofessional Care Team), an evaluation project to test the effectiveness of new delivery and payment systems for improving dental care and oral health. This is a parallel-group cluster randomized controlled trial. Fourteen rural Oregon counties with a publicly insured (Medicaid) population of 82,000 children (0 to 21 years old) and pregnant women served by a managed dental care organization are randomized into test and control counties. In the test intervention (PREDICT), allied dental personnel provide screening and preventive services in community settings and case managers serve as patient navigators to arrange referrals of children who need dentist services. The delivery system intervention is paired with a compensation system for high performance (pay-for-performance) with efficient performance monitoring. PREDICT focuses on the following: 1) identifying eligible children and gaining caregiver consent for services in community settings (for example, schools); 2) providing risk-based preventive and caries stabilization services efficiently at these settings; 3) providing curative care in dental clinics; and 4) incentivizing local delivery teams to meet performance benchmarks. In the control intervention, care is delivered in dental offices without performance incentives. The primary outcome is the prevalence of untreated dental caries. Other outcomes are related to process, structure and cost. Data are collected through patient and staff surveys, clinical examinations, and the review of health and administrative records. If effective, PREDICT is expected to substantially reduce disparities in dental care and oral health. PREDICT can be

  3. Etiology of Hypopituitarism in Adult Patients: The Experience of a Single Center Database in the Serbian Population

    Directory of Open Access Journals (Sweden)

    M. Doknić

    2017-01-01

    Full Text Available There are only a few published studies related to the population-based etiology of hypopituitarism. New risks for developing hypopituitarism have been recognized in the last 10 years. Aim. To present data regarding the etiology of hypopituitarism collected in a tertiary center over the last decade. This is a cross-sectional database study. Patients and Methods. We included 512 patients (pts with hypopituitarism, with a mean age of 45.9 ± 1.7 yrs (range: 18–82; male: 57.9%. Results. Nonfunctional pituitary adenomas were presented in 205 pts (40.5%, congenital causes in 74 pts (14.6%, while acromegaly and prolactinomas were presented in 37 (7.2% and 36 (7.0% patients, respectively. Craniopharyngiomas were detected in 30 pts (5.9%, and head trauma due to trauma brain injury-TBI and subarachnoid hemorrhage-SAH in 27 pts (5.4%. Survivors of hemorrhagic fever with renal syndrome (HFRS and those with previous cranial irradiation were presented in the same frequency (18 pts, 3.5% each. Conclusion. The most common causes of hypopituitarism in our database are pituitary adenomas. Increased awareness of the other causes of pituitary dysfunction, such as congenital, head trauma, extrapituitary cranial irradiation, and infections, is the reason for a higher frequency of these etiologies of hypopituitarism in the presented database.

  4. Etiology of Hypopituitarism in Adult Patients: The Experience of a Single Center Database in the Serbian Population

    Science.gov (United States)

    Pekić, S.; Miljić, D.; Popović, V.; Stojanović, M.; Petakov, M.

    2017-01-01

    There are only a few published studies related to the population-based etiology of hypopituitarism. New risks for developing hypopituitarism have been recognized in the last 10 years. Aim. To present data regarding the etiology of hypopituitarism collected in a tertiary center over the last decade. This is a cross-sectional database study. Patients and Methods. We included 512 patients (pts) with hypopituitarism, with a mean age of 45.9 ± 1.7 yrs (range: 18–82; male: 57.9%). Results. Nonfunctional pituitary adenomas were presented in 205 pts (40.5%), congenital causes in 74 pts (14.6%), while acromegaly and prolactinomas were presented in 37 (7.2%) and 36 (7.0%) patients, respectively. Craniopharyngiomas were detected in 30 pts (5.9%), and head trauma due to trauma brain injury-TBI and subarachnoid hemorrhage-SAH in 27 pts (5.4%). Survivors of hemorrhagic fever with renal syndrome (HFRS) and those with previous cranial irradiation were presented in the same frequency (18 pts, 3.5% each). Conclusion. The most common causes of hypopituitarism in our database are pituitary adenomas. Increased awareness of the other causes of pituitary dysfunction, such as congenital, head trauma, extrapituitary cranial irradiation, and infections, is the reason for a higher frequency of these etiologies of hypopituitarism in the presented database. PMID:28702053

  5. Population size, center-periphery, and seed dispersers' effects on the genetic diversity and population structure of the Mediterranean relict shrub Cneorum tricoccon.

    Science.gov (United States)

    Lázaro-Nogal, Ana; Matesanz, Silvia; García-Fernández, Alfredo; Traveset, Anna; Valladares, Fernando

    2017-09-01

    The effect of population size on population genetic diversity and structure has rarely been studied jointly with other factors such as the position of a population within the species' distribution range or the presence of mutualistic partners influencing dispersal. Understanding these determining factors for genetic variation is critical for conservation of relict plants that are generally suffering from genetic deterioration. Working with 16 populations of the vulnerable relict shrub Cneorum tricoccon throughout the majority of its western Mediterranean distribution range, and using nine polymorphic microsatellite markers, we examined the effects of periphery (peripheral vs. central), population size (large vs. small), and seed disperser (introduced carnivores vs. endemic lizards) on the genetic diversity and population structure of the species. Contrasting genetic variation ( H E : 0.04-0.476) was found across populations. Peripheral populations showed lower genetic diversity, but this was dependent on population size. Large peripheral populations showed high levels of genetic diversity, whereas small central populations were less diverse. Significant isolation by distance was detected, indicating that the effect of long-distance gene flow is limited relative to that of genetic drift, probably due to high selfing rates ( F IS  = 0.155-0.887), restricted pollen flow, and ineffective seed dispersal. Bayesian clustering also supported the strong population differentiation and highly fragmented structure. Contrary to expectations, the type of disperser showed no significant effect on either population genetic diversity or structure. Our results challenge the idea of an effect of periphery per se that can be mainly explained by population size, drawing attention to the need of integrative approaches considering different determinants of genetic variation. Furthermore, the very low genetic diversity observed in several small populations and the strong among-population

  6. Access to Educational Opportunity in Rural Communities: Alternative Patterns of Delivering Vocational Education in Sparsely Populated Areas. Volume 2: The Heartland Vocational Center: A Decentralized Center.

    Science.gov (United States)

    Thomas, Ruth G.; And Others

    One of the four case studies addressing access of rural students to vocational education through inter-school district cooperation, the Heartland case study represents the decentralized variation of the center cooperative school pattern, identifies essential features of this form of cooperation, details factors facilitating/impeding the…

  7. The Counseling Center Assessment of Psychological Symptoms (CCAPS-62): Acceptance, feasibility, and initial psychometric properties in a UK student population.

    Science.gov (United States)

    Broglia, Emma; Millings, Abigail; Barkham, Michael

    2017-09-01

    The burden and severity of student mental health continue to increase in parallel with increasing financial pressures on students and services alike. There is a need for a student-specific measure of distress that acknowledges their unique context. This study examined the feasibility, acceptance, and initial psychometric properties of a US measure, the Counseling Center Assessment of Psychological Symptoms (CCAPS), in a UK student sample. A sample of 294 UK help-seeking students from two universities completed the CCAPS-62 and Clinical Outcomes in Routine Evaluation (CORE-10) as a comparator. The factor solution and reliability of the CCAPS-62 were examined. Correlations and clinical boundaries were determined between the CCAPS-62 subscales and CORE-10, and comparisons were made with US published norms. The CCAPS-62 demonstrated a strong factor solution that matched the intended subscales. All subscales had good reliability and correlated significantly with the CORE-10. The agreement on caseness between the two measures was 92.8% with 86.3% reaching clinical threshold on both the CCAPS-62 and CORE-10. Severity was most noticeable for academic distress, depression, anxiety, and social anxiety. Compared to US data, UK students showed higher clinical severity for all psychological symptoms. The CCAPS-62 is a reliable and psychometrically valid assessment measure to use with UK students without revision. The overall distress indicated is similar to that of the CORE-10, but the individual subscales are more informative of specific student concerns including academic distress, social anxiety, and substance abuse. Potential benefits of administering a student-focused assessment measure in student counselling services are discussed. University students attending counselling in the UK demonstrate clinical severity for academic distress, depression, anxiety, and social anxiety. Compared to university students in the US, UK students present with higher clinical severity on

  8. Meeting the Needs of Chinese English Language Learners at Writing Centers in America: A Proposed Culturally Responsive Model

    Science.gov (United States)

    Wang, Peizhen; Machado, Crystal

    2015-01-01

    This paper describes the ways in which Writing Centers (WC) currently serve English Language Learners (ELL) at American universities. The authors argue that the pedagogy offered at these centers does not always meet the needs of the Chinese ELLs who make up the largest population of ELLs at American universities. The proposed supplemental model…

  9. Factors associated with the utilization of primary care emergency centers in a Spanish region with high population dispersion: a mixed-methods study.

    Science.gov (United States)

    Sanz-Barbero, Belén; Otero-García, Laura; Blasco-Hernández, Teresa; San Sebastián, Miguel

    2014-09-03

    Adequate access to primary care emergency centers is particularly important in rural areas isolated from urban centers. However, variability in utilization of emergency services located in primary care centers among inhabitants of nearby geographical areas is understudied. The objectives of this study are twofold: 1) to analyze the association between the availability of municipal emergency care centers and utilization of primary care emergency centers (PCEC), in a Spanish region with high population dispersion; and 2) to determine healthcare providers' perceptions regarding PCEC utilization. A mixed-methods study was conducted. Quantitative phase: multilevel logistic regression modeling using merged data from the 2003 Regional Health Survey of Castile and Leon and the 2001 census data (Spain). Qualitative phase:14 in-depth- interviews of rural-based PCEC providers. Having PCEC as the only emergency center in the municipality was directly associated with its utilization (p use. PCEC users were considered to be predominantly workers and students with scheduling conflicts with rural primary care opening hours. The location of emergency care centers is associated with PCEC utilization. Increasing access to primary care by extending hours may be an important step toward optimal PCEC utilization. Further research would determine whether lower PCEC use by certain groups is associated with disparities in access to care.

  10. Reach and messages of the world's largest ivory burn.

    Science.gov (United States)

    Braczkowski, Alexander; Holden, Matthew H; O'Bryan, Christopher; Choi, Chi-Yeung; Gan, Xiaojing; Beesley, Nicholas; Gao, Yufang; Allan, James; Tyrrell, Peter; Stiles, Daniel; Brehony, Peadar; Meney, Revocatus; Brink, Henry; Takashina, Nao; Lin, Ming-Ching; Lin, Hsien-Yung; Rust, Niki; Salmo, Severino G; Watson, James Em; Kahumbu, Paula; Maron, Martine; Possingham, Hugh P; Biggs, Duan

    2018-03-01

    Recent increases in ivory poaching have depressed African elephant populations. Successful enforcement has led to ivory being stockpiled. Stockpile destruction is becoming increasingly popular, and most destruction has occurred in the last five years. Ivory destruction is intended to send a strong message against ivory consumption, both in promoting a taboo on ivory use and catalyzing policy change. However, there has been no effort to establish the distribution and extent of media reporting on ivory destruction events globally. We analyze media coverage across eleven important nation states of the largest ivory destruction event in history (Kenya, 30 April 2016). We used a well-accepted online media crawling tool and key language translations to search online and print newspapers. We found most online news on the ivory burn came from the US (81% of articles), while print news was dominated by Kenya (61% of articles). We subjected online articles from five key countries and territories to content analysis and found 86-97% of all online articles reported the burn as a positive conservation action, while between 4-50% discussed ivory burning as having a negative impact on elephant conservation. Most articles discussed law enforcement and trade bans as effective for elephant conservation. There was more relative search interest globally on the 2016 Kenyan ivory burn than any other in five years. Our study is the first attempt to track the spread of media around an ivory burn and is a case study in tracking the effects of a conservation-marketing event. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  11. Medida da acuidade visual em um shopping center metropolitano Visual acuity measurement in a metropolitan shopping mall population

    Directory of Open Access Journals (Sweden)

    Giovanni M. Travi

    2000-04-01

    Full Text Available Objetivo: Determinar a prevalência de baixa acuidade visual (AV em uma amostra populacional, com um padrão socioeconômico diferenciado. Métodos: Realizou-se estudo de prevalência, sendo verificada a AV de 213 voluntários examinados em um posto no interior de um shopping center em Porto Alegre, por meio do aparelho Ortho-Rater, da Bausch & Lomb. Foi medida a AV para longe em todos os indivíduos e naqueles com 40 anos ou mais, a AV para perto, ambos sem e com correção. Determinou-se como baixa AV, aquela inferior a 10 (equivalente a 20/20 na Tabela de Snellen. Resultados: A idade variou de 6 a 75 anos, com uma média ± desvio-padrão de 27,8 ± 15,16 anos, pertencendo a maioria dos examinados à faixa entre 10 e 40 anos. Encontrou-se uma prevalência de 38,7% (IC 95%: 32,1-45,7 de baixa AV para longe nos dois olhos. 24,9% (IC 95%: 19,2-31,3 apresentavam déficit visual binocular e não faziam uso de correção. Para perto, observou-se que 70,8% (IC 95%: 55,9-83 dos indivíduos testados apresentaram déficit visual binocular sem correção e 41,7% (IC 95%: 27,6-56,8 apresentaram baixa AV independente do uso de correção. Conclusão: Este estudo demonstrou que existe considerável parcela da população com déficit visual, necessitando de avaliação e manejo adequados. Conclui-se que programas de medida da AV e orientação sobre saúde ocular são importantes em qualquer ambiente e atingindo diferentes classes socioeconômicas.Purpose: To determine the prevalence of low visual acuity (VA in a populational sample, with a differentiated social pattern. Methods: This was a prevalence study, in which the 213 volunteers' VA, examined in a shopping mall in Porto Alegre, was verified through the Ortho-Rater device, from Bausch & Lomb. Far sight VA was measured in all the individuals and in those who were 40 years old or older, near sight VA, both of them without and with correction. VA was considered low when it was less than 10 (equivalent

  12. Guaranteeing uptime at worl's largest particle physics lab

    CERN Multimedia

    Brodkin, Jon

    2007-01-01

    "As the European agency CERN was gearing up to build the world's largest particle accelerator, officials there knew they could not afford to have problems in their technical infrastructure cause any downtime." (1 page)

  13. Assessment of psychological dependence among tobacco users: A survey held among the rural population of India to call for attention of tobacco cessation centers.

    Science.gov (United States)

    Jadhav, Kiran; Singh, Dhanpal

    2013-07-01

    In India most of the tobacco cessation centers are concentrating only on urban population, whereas, literature reveals that it is rural population, which shows high frequency of consumption of tobacco. It is well known that high frequency of tobacco consumption is associated with psychological dependence. This study aimed at identifying, which form of tobacco consumption (smoking or smokeless) is associated with psychological dependence and is associated with which particular age group in rural population. It was a questionnaire based survey where 200 subjects were enrolled. Revised version of standard Fagerstrom Test for Nicotine dependence (FTND) was given to each subject to answer. The collected data was statistically analyzed by using Karl Pearson Correlation (r) test and Student's t-test. Study showed that subjects above 40 years of age are psychologically highly dependent on tobacco smoking as compared to tobacco chewing. Tobacco chewing is more prevalent among the younger population (20-30 years of age) and type of habit does not have any influence over psychological dependence below 40 years of age. A positive correlation was observed between duration of habit and psychological dependence in all age groups irrespective of type of the habit of tobacco consumption. This study attempts at creating a new avenue for the tobacco cessation centers where they can target their efforts towards rural population particularly people above 40 years of age with a tobacco smoking habit so that they can actually reduce the burden of a number of people at risk for developing tobacco associated oral cancer.

  14. Watching the Creation of Southern California's Largest Reservoir

    Science.gov (United States)

    2001-01-01

    The new Diamond Valley Lake Reservoir near the city of Hemet in Riverside County is billed as the largest earthworks construction project in U.S.history. Construction began in 1995 and involved 31 million cubic meters of foundation excavation and 84 million cubic meters of embankment construction. This set of MISR images captures the most recent phase in the reservoir's activation. At the upper left is a natural-color view acquired by the instrument's vertical-viewing (nadir) camera on March 14, 2000 (Terra orbit 1273), shortly after the Metropolitan Water District began filling the reservoir with water from the Colorado River and Northern California. Water appears darker than the surrounding land. The image at the upper right was acquired nearly one year later on March 1, 2001 (Terra orbit 6399), and shows a clear increase in the reservoir's water content. When full, the lake will hold nearly a trillion liters of water.According to the Metropolitan Water District, the 7 kilometer x 3 kilometer reservoir nearly doubles Southern California's above-groundwater storage capacity. In addition to routine water management, Diamond Valley Lake is designed to provide protection against drought and a six-month emergency supply in the event of earthquake damage to a major aqueduct. In the face of electrical power shortages, it is also expected to reduce dependence on the pumping of water from northern mountains during the high-demand summer months. An unexpected result of site excavation was the uncovering of mastodon and mammoth skeletons along with bones from extinct species not previously thought to have been indigenous to the area, such as the giant long-horned bison and North American lion. A museum and interpretive center is being built to protect these finds.The lower MISR image, from May 20, 2001 (Terra orbit 7564), is a false-color view combining data from the instrument's 26-degree forward view (displayed as blue) with data from the 26-degree backward view

  15. Joint Asymptotic Distributions of Smallest and Largest Insurance Claims

    Directory of Open Access Journals (Sweden)

    Hansjörg Albrecher

    2014-07-01

    Full Text Available Assume that claims in a portfolio of insurance contracts are described by independent and identically distributed random variables with regularly varying tails and occur according to a near mixed Poisson process. We provide a collection of results pertaining to the joint asymptotic Laplace transforms of the normalised sums of the smallest and largest claims, when the length of the considered time interval tends to infinity. The results crucially depend on the value of the tail index of the claim distribution, as well as on the number of largest claims under consideration.

  16. Challenges with the largest commercial hydrogen station in the world

    Energy Technology Data Exchange (ETDEWEB)

    Charbonneau, Thomas; Gauthier, Pierre [Air Liquide Canada (Canada)

    2010-07-01

    This abstract's objective is to share with the participants the story of the largest hydrogen fueling station made to this date and to kick-start the story, we will cover the challenges; first the technical ones; the operational ones; the distribution ones and; the financial ones. We will then move on to review the logistic (geographic) issues raised by the project and conclude our presentation by sharing the output values of the largest fueling station built so far in the world. (orig.)

  17. Family physicians' ability to perform population management is associated with adoption of other aspects of the patient-centered medical home.

    Science.gov (United States)

    Ottmar, Jessica; Blackburn, Brenna; Phillips, Robert L; Peterson, Lars E; Jaén, Carlos Roberto

    2015-04-01

    The patient-centered medical home (PCMH) model is considered a promising approach to improving population health, but how elements of these advanced practice models relate to population health capability is unknown. To measure associations between family physicians' performance of population management with PCMH components, a cross-sectional survey was conducted with physicians accessing the American Board of Family Medicine Web site in 2011. Bivariate analysis and logistic regression tested associations between physician and practice demographics and specific PCMH features. The primary outcome was performance of population management. The final sample included 3855 physicians, 37.3% of whom reported performing population management. Demographic characteristics significantly associated with greater use of population management were female sex and graduation from an international medical school. PCMH components that remained associated with population management after adjustment were access to clinical case managers (odds ratio [OR]=2.01, 95% confidence interval [95% CI]: 1.69, 2.39), behavioral health collaboration (OR=1.49, 95% CI: 1.26, 1.77), having an electronic health record that supports meaningful use (OR=1.47, 95% CI: 1.25, 1.74), recent participation in a quality improvement project (OR=2.47, 95% CI: 2.12, 2.89), and routine measurement of patient difficulty securing an appointment (OR=2.87, 95% CI: 2.45, 3.37). Performance of population management was associated with several PCMH elements and resources not present in traditional primary care offices. Attention to these elements likely will enhance delivery of population management services in primary care.

  18. NAFTA: The World's Largest Trading Zone Turns 20

    Science.gov (United States)

    Ferrarini, Tawni Hunt; Day, Stephen

    2014-01-01

    Everyone under the age of 20 who has grown up in North America has lived in the common market created by NAFTA--the North American Free Trade Agreement. In a zone linking the United States, Canada, and Mexico, most goods and investments flow freely across borders to users, consumers, and investors. In 1994, NAFTA created the largest relatively…

  19. Synchrotron Emission on the Largest Scales: Radio Detection of the ...

    Indian Academy of Sciences (India)

    Abstract. Shocks and turbulence generated during large-scale structure formation are predicted to produce large-scale, low surface-brightness synchrotron emission. On the largest scales, this emission is globally correlated with the thermal baryon distribution, and constitutes the 'syn- chrotron cosmic-web'. I present the ...

  20. Building Earth's Largest Library: Driving into the Future.

    Science.gov (United States)

    Coffman, Steve

    1999-01-01

    Examines the Amazon.com online bookstore as a blueprint for designing the world's largest library. Topics include selection; accessibility and convenience; quality of Web sites and search tools; personalized service; library collection development, including interlibrary loan; library catalogs and catalog records; a circulation system; costs;…

  1. Analysis of Human Standing Balance by Largest Lyapunov Exponent

    Directory of Open Access Journals (Sweden)

    Kun Liu

    2015-01-01

    Full Text Available The purpose of this research is to analyse the relationship between nonlinear dynamic character and individuals’ standing balance by the largest Lyapunov exponent, which is regarded as a metric for assessing standing balance. According to previous study, the largest Lyapunov exponent from centre of pressure time series could not well quantify the human balance ability. In this research, two improvements were made. Firstly, an external stimulus was applied to feet in the form of continuous horizontal sinusoidal motion by a moving platform. Secondly, a multiaccelerometer subsystem was adopted. Twenty healthy volunteers participated in this experiment. A new metric, coordinated largest Lyapunov exponent was proposed, which reflected the relationship of body segments by integrating multidimensional largest Lyapunov exponent values. By using this metric in actual standing performance under sinusoidal stimulus, an obvious relationship between the new metric and the actual balance ability was found in the majority of the subjects. These results show that the sinusoidal stimulus can make human balance characteristics more obvious, which is beneficial to assess balance, and balance is determined by the ability of coordinating all body segments.

  2. Worlds largest particle physics laboratory selects Proxim Wireless Mesh

    CERN Multimedia

    2007-01-01

    "Proxim Wireless has announced that the European Organization for Nuclear Research (CERN), the world's largest particle physics laboratory and the birthplace of the World Wide Web, is using it's ORiNOCO AP-4000 mesh access points to extend the range of the laboratory's Wi-Fi network and to provide continuous monitoring of the lab's calorimeters" (1/2 page)

  3. PNNL supercomputer to become largest computing resource on the Grid

    CERN Multimedia

    2002-01-01

    Hewlett Packard announced that the US DOE Pacific Northwest National Laboratory will connect a 9.3-teraflop HP supercomputer to the DOE Science Grid. This will be the largest supercomputer attached to a computer grid anywhere in the world (1 page).

  4. Toward sustainable harvesting of Africa's largest medicinal plant ...

    African Journals Online (AJOL)

    Global demand for treating prostate disorders with Prunus africana bark extract has made P. africana Africa's largest medicinal plant export. Unsustainable harvesting practices can lead to local extirpations of this multipurpose tree. Survey research targeting P. africana harvesters in a Tanzania forest reserve revealed that ...

  5. Assessment of psychological dependence among tobacco users: A survey held among the rural population of India to call for attention of tobacco cessation centers

    Directory of Open Access Journals (Sweden)

    Kiran Jadhav

    2013-01-01

    Full Text Available Background: In India most of the tobacco cessation centers are concentrating only on urban population, whereas, literature reveals that it is rural population, which shows high frequency of consumption of tobacco. It is well known that high frequency of tobacco consumption is associated with psychological dependence. This study aimed at identifying, which form of tobacco consumption (smoking or smokeless is associated with psychological dependence and is associated with which particular age group in rural population. Materials and Methods: It was a questionnaire based survey where 200 subjects were enrolled. Revised version of standard Fagerstrom Test for Nicotine dependence (FTND was given to each subject to answer. The collected data was statistically analyzed by using Karl Pearson Correlation (r test and Student′s t-test. Results: Study showed that subjects above 40 years of age are psychologically highly dependent on tobacco smoking as compared to tobacco chewing. Tobacco chewing is more prevalent among the younger population (20-30 years of age and type of habit does not have any influence over psychological dependence below 40 years of age. A positive correlation was observed between duration of habit and psychological dependence in all age groups irrespective of type of the habit of tobacco consumption. Conclusion: This study attempts at creating a new avenue for the tobacco cessation centers where they can target their efforts towards rural population particularly people above 40 years of age with a tobacco smoking habit so that they can actually reduce the burden of a number of people at risk for developing tobacco associated oral cancer.

  6. Using ACHIS to Analyze Nursing Health Promotion Interventions for Vulnerable Populations in a Community Nursing Center: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Woi-Hyun S. Hong

    2009-09-01

    Conclusion: This research adds to the understanding of the importance of nurses' interventions toward health promotion with the vulnerable population. This preliminary analysis suggests that the ACHIS provide a clinical information system for collecting, storing, processing, retrieving, and managing clinical data in a data repository. [Asian Nursing Research 2009;3(3:130–138

  7. The Community Health Applied Research Network (CHARN) Data Warehouse: a Resource for Patient-Centered Outcomes Research and Quality Improvement in Underserved, Safety Net Populations.

    Science.gov (United States)

    Laws, Reesa; Gillespie, Suzanne; Puro, Jon; Van Rompaey, Stephan; Quach, Thu; Carroll, Joseph; Weir, Rosy Chang; Crawford, Phil; Grasso, Chris; Kaleba, Erin; McBurnie, Mary Ann

    2014-01-01

    The Community Health Applied Research Network, funded by the Health Resources and Services Administration, is a research network comprising 18 Community Health Centers organized into four Research Nodes (each including an academic partner) and a data coordinating center. The network represents more than 500,000 diverse safety net patients across 11 states. The primary objective of this paper is to describe the development and implementation process of the CHARN data warehouse. The methods involved regulatory and governance development and approval, development of content and structure of the warehouse and processes for extracting the data locally, performing validation, and finally submitting data to the data coordinating center. Version 1 of the warehouse has been developed. Tables have been added, the population and the years of electronic health records (EHR) have been expanded for Version 2. It is feasible to create a national, centralized data warehouse with multiple Community Health Center partners using different EHR systems. It is essential to allow sufficient time: (1) to develop collaborative, trusting relationships among new partners with varied technology, backgrounds, expertise, and interests; (2) to complete institutional, business, and regulatory review processes; (3) to identify and address technical challenges associated with diverse data environments, practices, and resources; and (4) to provide continuing data quality assessments to ensure data accuracy.

  8. Statistics of the largest sunspot and facular areas per solar cycle

    International Nuclear Information System (INIS)

    Willis, D.M.; Kabasakal Tulunay, Y.

    1979-01-01

    The statistics of extreme values is used to investigate the statistical properties of the largest areas sunspots and photospheric faculae per solar cycle. The largest values of the synodic-solar-rotation mean areas of umbrae, whole spots and faculae, which have been recorded for nine solar cycles, are each shown to comply with the general form of the extreme value probability function. Empirical expressions are derived for the three extreme value populations from which the characteristic statistical parameters, namely the mode, median, mean and standard deviation, can be calculated for each population. These three extreme value populations are also used to find the expected ranges of the extreme areas in a group of solar cycles as a function of the number of cycles in the group. The extreme areas of umbrae and whole spots have a dispersion comparable to that found by Siscoe for the extreme values of sunspot number, whereas the extreme areas of faculae have a smaller dispersion which is comparable to that found by Siscoe for the largest geomagnetic storm per solar cycle. The expected range of the largest sunspot area per solar cycle for a group of one hundred cycles appears to be inconsistent with the existence of the prolonged periods of sunspot minima that have been inferred from the historical information on solar variability. This inconsistency supports the contention that there are temporal changes of solar-cycle statistics during protracted periods of sunspot minima (or maxima). Indeed, without such temporal changes, photospheric faculae should have been continually observable throughout the lifetime of the Sun. (orig.)

  9. Optimizing Data Center Services to Foster Stewardship and Use of Geospatial Data by Heterogeneous Populations of Users

    Science.gov (United States)

    Downs, R. R.; Chen, R. S.; de Sherbinin, A. M.

    2017-12-01

    Growing recognition of the importance of sharing scientific data more widely and openly has refocused attention on the state of data repositories, including both discipline- or topic-oriented data centers and institutional repositories. Data creators often have several alternatives for depositing and disseminating their natural, social, health, or engineering science data. In selecting a repository for their data, data creators and other stakeholders such as their funding agencies may wish to consider the user community or communities served, the type and quality of data products already offered, and the degree of data stewardship and associated services provided. Some data repositories serve general communities, e.g., those in their host institution or region, whereas others tailor their services to particular scientific disciplines or topical areas. Some repositories are selective when acquiring data and conduct extensive curation and reviews to ensure that data products meet quality standards. Many repositories have secured credentials and established a track record for providing trustworthy, high quality data and services. The NASA Socioeconomic Data and Applications Center (SEDAC) serves users interested in human-environment interactions, including researchers, students, and applied users from diverse sectors. SEDAC is selective when choosing data for dissemination, conducting several reviews of data products and services prior to release. SEDAC works with data producers to continually improve the quality of its open data products and services. As a Distributed Active Archive Center (DAAC) of the NASA Earth Observing System Data and Information System, SEDAC is committed to improving the accessibility, interoperability, and usability of its data in conjunction with data available from other DAACs, as well as other relevant data sources. SEDAC is certified as a Regular Member of the International Council for Science World Data System (ICSU-WDS).

  10. Understanding Population.

    Science.gov (United States)

    Mothner, Ira

    Activities and concerns of Ford Foundation supported population research and training centers are described in this report. The centers are concerned with population growth, consequences of growth for human welfare, forces that determine family planning, interrelations among population variables, economics of contraceptive distribution, and…

  11. Temporal properties of seismicity and largest earthquakes in SE Carpathians

    Directory of Open Access Journals (Sweden)

    S. Byrdina

    2006-01-01

    Full Text Available In order to estimate the hazard rate distribution of the largest seismic events in Vrancea, South-Eastern Carpathians, we study temporal properties of historical and instrumental catalogues of seismicity. First, on the basis of Generalized Extreme Value theory we estimate the average return period of the largest events. Then, following Bak et al. (2002 and Corral (2005a, we study scaling properties of recurrence times between earthquakes in appropriate spatial volumes. We come to the conclusion that the seismicity is temporally clustered, and that the distribution of recurrence times is significantly different from a Poisson process even for times largely exceeding corresponding periods of foreshock and aftershock activity. Modeling the recurrence times by a gamma distributed variable, we finally estimate hazard rates with respect to the time elapsed from the last large earthquake.

  12. Worlds Largest Wave Energy Project 2007 in Wales

    DEFF Research Database (Denmark)

    Christensen, Lars; Friis-Madsen, Erik; Kofoed, Jens Peter

    2006-01-01

    This paper introduces world largest wave energy project being developed in Wales and based on one of the leading wave energy technologies. The background for the development of wave energy, the total resource ands its distribution around the world is described. In contrast to wind energy turbines...... Dragon has to be scaled in accordance with the wave climate at the deployment site, which makes the Welch demonstrator device the worlds largest WEC so far with a total width of 300 meters. The project budget, the construction methods and the deployment site are also given....... a large number of fundamentally different technologies are utilised to harvest wave energy. The Wave Dragon belongs to the wave overtopping class of converters and the paper describes the fundamentals and the technical solutions used in this wave energy converter. An offshore floating WEC like the Wave...

  13. Upgrade and modernization of the six largest HPPs in Macedonia

    International Nuclear Information System (INIS)

    Hadzievska, M.

    2002-01-01

    In 1998, Electric Power Company of Macedonia and the International Bank for Development and Reconstruction, started the Power System Improvement Project a part of which is the Project for rehabilitation of the six largest Hydro Power Plants (HPPs) in the Republic of Macedonia. The six largest Hydro Power Plants (HPP Vrutok, HPP Raven, HPP Globocica, HPP Tikves and HPP Spilje and HPP Vrben) represent 91% of the country's hydropower capacity. The rehabilitation program is divided in five parts (contracts) and covers the refurbishment of: turbine runners, turbine and generator bearings, governors, inlet valves; butterfly valves, including accessories and control systems; generators, excitation system and voltage regulation; control system, protection and LV auxiliaries; switch gears and control gears in 220 kV, 110 kV and 35 kV substations. At the moment, only the implementation of switch gears has started, the first phase is already finished, and 50 % of the rehabilitation works for HPP Vrutok, the largest HPP, has been finished. With the realization of this project, greater hydropower production is expected. It also expected that HPPs will become a more vital part of the Macedonian power system

  14. Kabob report. Pt. 3. Chevron plant largest in Canada

    Energy Technology Data Exchange (ETDEWEB)

    1971-01-18

    Canada's largest fully integrated primary natural- gas processing and sulfur recovery plant is heading for physical completion by mid-summer of 1971. The Ralph M. Parsons Construction Co. of Canada Ltd., contractor for the S. Kaybob Beaverhill Lake Unit No. 3 gas-processing plant, to be operated by Chevron Standard Ltd., estimates completion by June 30. After that the $80 million complex will have tests and running in time. With any reasonable luck, it should be fully on stream by late summer. Preliminary construction on the 200-acre site started in Jan. 1969 with clearing and contouring of the main plant and sulfur storage sites. Initial rough grading started in the early summer, after spring breakup was over. Delivery of most of the big items was made by rail because the local secondary roads were inadequate for them. Concrete has been a large item. The contractor has its own batch plant on the site for the estimated 28,000 cu yd which will be needed for the whole job. Dominating the construction site from the start has been the high sulfur plant stack, first of the major items to be finished. It will serve to dispose of effluent from the largest sulfur recovery unit in Canada. It is 465 ft high, one of the largest in Alberta, and a significant contribution to pollution control and environmental protection.

  15. Towards a Unified Taxonomy of Health Indicators: Academic Health Centers and Communities Working Together to Improve Population Health

    Science.gov (United States)

    Ahmed, Syed; Franco, Zeno; Kissack, Anne; Gabriel, Davera; Hurd, Thelma; Ziegahn, Linda; Bates, Nancy J.; Calhoun, Karen; Carter-Edwards, Lori; Corbie-Smith, Giselle; Eder, Milton “Mickey”; Ferrans, Carol; Hacker, Karen; Rumala, Bernice B.; Strelnick, A. Hal; Wallerstein, Nina

    2014-01-01

    The Clinical and Translational Science Awards (CTSA) program represents a significant public investment. To realize its major goal of improving the public’s health and reducing health disparities, the CTSA Consortium’s Community Engagement Key Function Committee has undertaken the challenge of developing a taxonomy of community health indicators. The objective is to initiate a unified approach for monitoring progress in improving population health outcomes. Such outcomes include, importantly, the interests and priorities of community stakeholders, plus the multiple, overlapping interests of universities and of the public health and health care professions involved in the development and use of local health care indicators. The emerging taxonomy of community health indicators that the authors propose supports alignment of CTSA activities and facilitates comparative effectiveness research across CTSAs, thereby improving the health of communities and reducing health disparities. The proposed taxonomy starts at the broadest level, determinants of health; subsequently moves to more finite categories of community health indicators; and, finally, addresses specific quantifiable measures. To illustrate the taxonomy’s application, the authors have synthesized 21 health indicator projects from the literature and categorized them into international, national, or local/special jurisdictions. They furthered categorized the projects within the taxonomy by ranking indicators with the greatest representation among projects and by ranking the frequency of specific measures. They intend for the taxonomy to provide common metrics for measuring changes to population health and, thus, extend the utility of the CTSA Community Engagement Logic Model. The input of community partners will ultimately improve population health. PMID:24556775

  16. Are Cancer incidence Rates Among Present And Past Workers Of The research Centers Of The Atomic Energy Commission higher Than The Rates Among The General Population?

    International Nuclear Information System (INIS)

    Litai, D.

    1999-01-01

    Cancer incidence rates among the workers of the AEC and its retirees have increased several fold in the last decade compared to the rates experienced in previous ones. This has brought about a wave of claims for compensation with negative repercussions in the media about the state of radiation safety in the nuclear research centers in the country. The Nuclear Research Center - Negev, being, generally closed to public and media visits, has taken the brunt of this criticism. Consequently, the question spelled out in the title has caused much concern and deserves to be discussed and explained. The purpose of this paper is to review what we know in this context and to show that the observed morbidity rates, worrying as they may be, are entirely natural, and, by and large, unrelated to the occupational exposures of the workers. It is well known that cancer incidence rates in the population rise steeply with age, especially over 50. As both research centers are approaching the age of 40, it is clear that a very large fraction of the workers and all retirees have passed this age and many are already in their sixties and even seventies. It is a well established fact that close to 40% of the population in this country (and many others as well) develop some type of cancer during their lifetime and close to a half of these succumb to it. As most of those cancers occur after the age of 50, this explains the increased rates alluded to above. Notably, numerous research centers around the globe have reached similar ages in the last decade and experience similar increases in morbidity, that have caused understandable concern and the initiation of epidemiological studies intended to identify the health effects of extended exposures to low doses, if any. Such studies have been carried out in several countries and followed, altogether, about 100,000 workers through 40 years. The studies showed no excess of cancer mortality among workers compared to the general population (adjusted

  17. Infection prevention and control and the refugee population: Experiences from the University of Louisville Global Health Center.

    Science.gov (United States)

    Carrico, Ruth M; Goss, Linda; Wiemken, Timothy L; Bosson, Rahel S; Peyrani, Paula; Mattingly, William A; Pauly, Allison; Ford, Rebecca A; Kotey, Stanley; Ramirez, Julio A

    2017-06-01

    During 2016, approximately 140,000 individuals entered the United States as part of the federal government refugee resettlement program and established themselves in communities in virtually every state. No national database regarding refugee health currently exists; therefore, little is known about existing infectious diseases, conditions, and cultural practices that impact successful acculturation. The objective of this report is to identify what is currently known about refugees and circumstances important to infection prevention and control with respect to their roles as new community members, employees, and consumers of health care. Using data from the University of Louisville Global Health Center's Newly Arriving Refugee Surveillance System, health issues affecting refugees from the perspective of a community member, an employee, and a patient were explored. Lack of immunity to vaccine-preventable diseases is the most widespread issue impacting almost every adult, adolescent, and child refugee resettled in Kentucky. Health issues of concern from an infection prevention and control perspective include latent tuberculosis infection, HIV, hepatitis B, hepatitis C, syphilis, and parasites. Other health conditions that may also be important include anemia, obesity, oral health, diabetes, and cardiovascular disease. Refugee resettlement provides motivation for collaborative work among those responsible for infection prevention and control in all settings, their public health partners, and those responsible for and interested in community workforce concerns. Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  18. Development of a wellness trust to improve population health: Case-study of a United States urban center

    Directory of Open Access Journals (Sweden)

    Diana Romero

    2018-06-01

    Full Text Available Across the United States health systems are recognizing the urgency of addressing the social determinants of health in order to improve population health. Wellness trusts, modeled after financial trusts support primary health prevention in community settings, provide an innovative opportunity for better community-clinical linkages, collaboration, and impact. This study aimed to understand the necessary tenets for a wellness trust in Brooklyn, New York (USA and examined community interest and political will; administrative, financing, and leadership structures; and metrics and data sources to monitor and assess impact. We employed a multi-method design. Key informant interviews (KIIs (n = 15 were conducted from 7/2016 to 1/2017. A content analysis of grey literature was used to analyze community interest and political will (n = 38. Extant datasets, such as New York City Community District profiles, were reviewed, and a narrative review was used to assess cost-effectiveness of prevention interventions (n = 33. The KIIs and grey literature underwent thematic analysis. Findings indicated healthcare issues dominated the health agenda despite recognition of social determinants of health. Braided funding (discrete funds that are coordinated but tracked separately and blended funding (funds pooled from multiple sources tracked together are common funding mechanisms. Robust data systems exist to assess impact. Indicators should address social determinants, performance and impact, be measurable, geographically specific, and include communities. Wellness trusts should be sustainable, engage communities, foster collaboration, and have adequate capacity. The Collective Impact Framework, a mechanism to coordinate and maximize efforts, offers this organizational structure. Wellness trusts are promising mechanisms to advance population health. Keywords: Wellness trusts, Mixed-methods design, Collective Impact Framework, Primary prevention

  19. The Environmental Responsibility of the World’s Largest Banks

    Directory of Open Access Journals (Sweden)

    Ryszawska Bożena

    2018-03-01

    Full Text Available Sustainability transition is changing the role and function of banks, specially their products and services also in relation to stakeholders. Banks are one of the main actors supporting the transition to sustainable economy. The purpose of this study is to emphasise the role of world’s largest banks in that process. Banks are slowly responding to the new demand of sustainability and responsibility, and they try to align with it. The paper is based on an overview of the world’s five largest banks that employ corporate social responsibility (CSR reporting standards, together with detailed enumeration of pro-environmental activities included in the reports. The first section of this paper presents the most popular approaches to the problem at hand, as reported in professional literature. Section two presents the characteristics of the CSR actions in banks. The third section discusses the environmental actions of the biggest banks in Global Reporting Initiative (GRI reporting the most popular standard for reporting non-financial information. And the last part of the paper presents the conclusions resulting from the article. The research was conducted using a variety of sources, such as scientific articles, statistical data, CSR reports of the world’s largest banks, as well reporting principles and standard disclosures. The basic method used in the process of writing was a critical analysis of literature and reports concerning the CSR reporting standards, environmental responsibilities of different kinds of entities, as well as own observations based on special reports of banks. In the article, also the analysis of financial market data, induction method and comparison method have been used. The main conclusions of the analysis of the CSR reports disclosed by the world’s largest banks confirm all three of the theses presented in the article. The findings suggest that the banks under study can be regarded as environmentally responsible

  20. Longevity in Calumma parsonii, the World's largest chameleon.

    Science.gov (United States)

    Tessa, Giulia; Glaw, Frank; Andreone, Franco

    2017-03-01

    Large body size of ectothermic species can be correlated with high life expectancy. We assessed the longevity of the World's largest chameleon, the Parson's chameleon Calumma parsonii from Madagascar by using skeletochronology of phalanges taken from preserved specimens held in European natural history museums. Due to the high bone resorption we can provide only the minimum age of each specimen. The highest minimum age detected was nine years for a male and eight years for a female, confirming that this species is considerably long living among chameleons. Our data also show a strong correlation between snout-vent length and estimated age. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Environmental isotope signatures of the largest freshwater lake in Kerala

    International Nuclear Information System (INIS)

    Unnikrishnan Warrier, C.

    2007-01-01

    Sasthamkotta lake, the largest freshwater lake in Kerala, serves as a source for drinking water for more than half a million people. Environmental 137 Cs analysis done on undisturbed sediment core samples reveals that the recent rate of sedimentation is not uniform in the lake. The useful life of lake is estimated as about 800 years. The δD and δ 18 O values of the lake waters indicate that the lake is well mixed with a slight variation horizontally. The stable isotope studies on well waters from the catchment indicate hydraulic communication with the lake and lake groundwater system is flow-through type. Analytical model also supports this view. (author)

  2. RAVEN AND THE CENTER OF MAFFEI 1: MULTI-OBJECT ADAPTIVE OPTICS OBSERVATIONS OF THE CENTER OF A NEARBY ELLIPTICAL GALAXY AND THE DETECTION OF AN INTERMEDIATE AGE POPULATION

    Energy Technology Data Exchange (ETDEWEB)

    Davidge, T. J.; Andersen, D. R. [Dominion Astrophysical Observatory, National Research Council of Canada, 5071 West Saanich Road, Victoria, BC V9E 2E7 (Canada); Lardière, O.; Bradley, C.; Blain, C. [Department of Mechanical Engineering, University of Victoria, Victoria, BC V8W 3P2 (Canada); Oya, S. [Subaru Telescope, National Optical Observatory of Japan Hilo, HI 96720 (United States); Akiyama, M.; Ono, Y. H., E-mail: tim.davidge@nrc.ca, E-mail: david.andersen@nrc.ca, E-mail: lardiere@uvic.ca, E-mail: cbr@uvic.ca, E-mail: celia.blain@gmail.com, E-mail: oya@subaru.naoj.org, E-mail: akiyama@astr.tohoku.ac.jp, E-mail: yo-2007@astr.tohoku.ac.jp [Astronomical Institute, Tohoku University 6–3 Aramaki, Aoba-ku, Sedai, 980-8578 Japan (Japan)

    2015-10-01

    Near-infrared (NIR) spectra that have an angular resolution of ∼0.15 arcsec are used to examine the stellar content of the central regions of the nearby elliptical galaxy Maffei 1. The spectra were recorded at the Subaru Telescope, with wavefront distortions corrected by the RAVEN Multi-object Adaptive Optics science demonstrator. The Ballick–Ramsey C{sub 2} absorption bandhead near 1.76 μm is detected, and models in which ∼10%–20% of the light near 1.8 μm originates from stars of spectral type C5 reproduce the depth of this feature. Archival NIR and mid-infrared images are also used to probe the structural and photometric properties of the galaxy. Comparisons with models suggest that an intermediate age population dominates the spectral energy distribution between 1 and 5 μm near the galaxy center. This is consistent not only with the presence of C stars, but also with the large Hβ index that has been measured previously for Maffei 1. The J − K color is more or less constant within 15 arcsec of the galaxy center, suggesting that the brightest red stars are well-mixed in this area.

  3. Presentation, Management, and Outcome of Thyroglossal Duct Cysts in Adult and Pediatric Populations: A 14-Year Single Center Experience

    Directory of Open Access Journals (Sweden)

    Hassan Al-Thani

    2016-07-01

    Full Text Available Objectives: A thyroglossal duct cyst (TDC is a frequent congenital midline anomaly of the neck that usually manifests during the first decade of life. We aimed to describe the presentation, management, and outcome of TDC in pediatric and adult cases. Methods: A retrospective observational analysis was conducted for all patients diagnosed and treated for TDC between 2000 and 2014 in a single center in Qatar. Data included patients’ demographics, presentations, preoperative investigations, anesthesia type, histopathological findings, surgical management, recurrences, and complications. Results: We identified 102 patients, of which 57% were males. The mean age of patients was 20.2±15.6 years. A bimodal distribution of TDC has been observed, which peaked between the ages of 6–13 years and at ≥19 years. The preoperative evaluation mainly includes ultrasonography (66%, thyroid function test (44%, and fine-needle aspiration cytology (10%. The median size of the cyst was 25 (2–60 mm. Patients mainly presented with an asymptomatic midline neck mass at or below the hyoid bone (82%, followed by fistula (9%, infection (2%, and dysphagia (2%. Eighty-nine cases were identified preoperatively as TDC. The histopathological findings confirmed TDC with hyoid bone in 61 cases, and TDC alone in 38 cases. Eighty patients underwent the Sistrunk procedure while excision of TDC alone was observed in 18 cases. Five cases of recurrent disease were also treated. Adults had a greater median cyst size (30 (9–60 vs. 22 (2–55 mm; p = 0.005 and required prolonged operation time (69 (1–169 vs. 32.5 (1–140 mins; p = 0.004 compared to the pediatric group. Conclusion: The occurrence of TDC shows a bimodal age distribution. Preoperative evaluation and time for surgery vary whereas clinical presentations, surgical management, and postoperative outcomes are comparable among adult and pediatric groups. Ultrasonography is the preferred diagnostic modality, and the

  4. Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain.

    Directory of Open Access Journals (Sweden)

    Carme Roca

    2011-04-01

    Full Text Available The epidemiology of Chagas disease, until recently confined to areas of continental Latin America, has undergone considerable changes in recent decades due to migration to other parts of the world, including Spain. We studied the prevalence of Chagas disease in Latin American patients treated at a health center in Barcelona and evaluated its clinical phase. We make some recommendations for screening for the disease.We performed an observational, cross-sectional prevalence study by means of an immunochromatographic test screening of all continental Latin American patients over the age of 14 years visiting the health centre from October 2007 to October 2009. The diagnosis was confirmed by serological methods: conventional in-house ELISA (cELISA, a commercial kit (rELISA and ELISA using T cruzi lysate (Ortho-Clinical Diagnostics (oELISA. Of 766 patients studied, 22 were diagnosed with T. cruzi infection, showing a prevalence of 2.87% (95% CI, 1.6-4.12%. Of the infected patients, 45.45% men and 54.55% women, 21 were from Bolivia, showing a prevalence in the Bolivian subgroup (n=127 of 16.53% (95% CI, 9.6-23.39%. ALL THE INFECTED PATIENTS WERE IN A CHRONIC PHASE OF CHAGAS DISEASE: 81% with the indeterminate form, 9.5% with the cardiac form and 9.5% with the cardiodigestive form. All patients infected with T. cruzi had heard of Chagas disease in their country of origin, 82% knew someone affected, and 77% had a significant history of living in adobe houses in rural areas.We found a high prevalence of T. cruzi infection in immigrants from Bolivia. Detection of T. cruzi-infected persons by screening programs in non-endemic countries would control non-vectorial transmission and would benefit the persons affected, public health and national health systems.

  5. Analysis of Genetic Diversity and Population Structure of Sesame Accessions from Africa and Asia as Major Centers of Its Cultivation

    Directory of Open Access Journals (Sweden)

    Komivi Dossa

    2016-04-01

    Full Text Available Sesame is an important oil crop widely cultivated in Africa and Asia. Understanding the genetic diversity of accessions from these continents is critical to designing breeding methods and for additional collection of sesame germplasm. To determine the genetic diversity in relation to geographical regions, 96 sesame accessions collected from 22 countries distributed over six geographic regions in Africa and Asia were genotyped using 33 polymorphic SSR markers. Large genetic variability was found within the germplasm collection. The total number of alleles was 137, averaging 4.15 alleles per locus. The accessions from Asia displayed more diversity than those from Africa. Accessions from Southern Asia (SAs, Eastern Asia (EAs, and Western Africa (WAf were highly diversified, while those from Western Asia (WAs, Northern Africa (NAf, and Southeastern Africa (SAf had the lowest diversity. The analysis of molecular variance revealed that more than 44% of the genetic variance was due to diversity among geographic regions. Five subpopulations, including three in Asia and two in Africa, were cross-identified through phylogenetic, PCA, and STRUCTURE analyses. Most accessions clustered in the same population based on their geographical origins. Our results provide technical guidance for efficient management of sesame genetic resources in breeding programs and further collection of sesame germplasm from these different regions.

  6. Place matters: A longitudinal analysis measuring the association between neighbourhood walkability and walking by age group and population center size in Canada.

    Science.gov (United States)

    Wasfi, Rania; Steinmetz-Wood, Madeleine; Kestens, Yan

    2017-01-01

    This study examined the influence of walkability on walking behaviour and assessed whether associations varied according to life-stage and population center (PC) size. Walkability scores were obtained for the six-digit postal codes of residential neighbourhoods of 11,200 Canadians, who participated in biennial assessments of the National Population Health Survey from 1994 to 2010. Participants were stratified by age-group. Mixed-effects logistic regression models were used to estimate the influence of cumulative exposure to neighborhood walkability on utilitarian and exercise walking by PC size and life-stage. Associations of neighbourhood walkability with utilitarian and exercise walking varied according to age-group and PC size. Exposure to high walkable neighborhoods was associated with utilitarian walking in younger and older adults in all PC sizes, except for older adults living in a medium PC. Living in a highly walkable neighborhood in a large PC was associated with walking for exercise in younger (OR: 1.42; 95%CI: 1.20-1.67) and older adults (OR: 2.09; 95%CI: 1.51-2.89). Living in highly walkable neighbourhood in a medium PC was associated with walking for exercise in older adults (OR: 1.62; 95%CI: 1.15-2.29). These results emphasize the need to consider the size and nature of every community, and the age-group of a population when implementing strategies to promote walking.

  7. Evaluation of prostate cancer prevalence in Iranian male population with increased PSA level, a one center experience

    International Nuclear Information System (INIS)

    Moslemi, Mohammad Kazem; Lotfi, Fariborz; Tahvildar, Seyed Ali

    2011-01-01

    This study was conducted to evaluate the incidence of prostate cancer (PCa) in Iranian male patients with increased prostate-specific antigen (PSA), and normal or abnormal digital rectal examination (DRE) that underwent prostate biopsy. From March 2006 to April 2009, a total of 346 consecutive males suspected of having PCa due to increased PSA levels underwent transrectal ultrasonography (TRUS)-guided sextant biopsy of the prostate. The total PSA (tPSA), demographic data, incidence of PCa, benign prostate hyperplasia (BPH), and prostatitis were assessed. The patients were divided into two groups according to their PSA values (group A serum tPSA level, 4–10 ng/mL; group B serum tPSA level, 10.1–20.0 ng/mL). Of the 346 biopsied cases, 193 cases (56%) had PCa, 80 cases (23%) had BPH, and 73 cases (21%) had prostatitis. The mean PSA and the age of the carcinoma group were significantly higher than those of the benign group (P < 0.01). The biopsy results were grouped as PCa, BPH, and prostatitis. Incidence of PCa for group A and group B cases were 115 cases (51%), and 78 cases (65%), respectively. In the case of PCa, BPH, and prostatitis, the mean PSAs were 10.02 ng/mL, 8.76 ng/mL, and 8.41 ng/mL, respectively (P < 0.40). TRUS-guided prostate biopsy and interpretation by a skilled team is highly recommended for early detection of PCa or its ruling-out. It seems that a PSA cutoff value of 4 ng/mL may be applied to the Iranian population. Although the chance of PCa is high in the PSA levels of 4–10 ng/mL, the combination of some data, like age and prostate volume, can decrease the rate of unnecessary prostate biopsies. We recommend prostate biopsy when PSA and/or DRE is elevated in symptomatic patients with obstructive and/or irritative lower urinary tract symptoms (LUTS) such as dysuria, frequency, or nocturia. Due to the very high incidence of PCa in the patients with PSA greater than 10 ng/mL, TRUS-guided biopsy is indicated, whatever the findings on DRE and

  8. Carbon and energy fluxes from China's largest freshwater lake

    Science.gov (United States)

    Gan, G.; LIU, Y.

    2017-12-01

    Carbon and energy fluxes between lakes and the atmosphere are important aspects of hydrology, limnology, and ecology studies. China's largest freshwater lake, the Poyang lake experiences tremendous water-land transitions periodically throughout the year, which provides natural experimental settings for the study of carbon and energy fluxes. In this study, we use the eddy covariance technique to explore the seasonal and diurnal variation patterns of sensible and latent heat fluxes of Poyang lake during its high-water and low-water periods, when the lake is covered by water and mudflat, respectively. We also determine the annual NEE of Poyang lake and the variations of NEE's components: Gross Primary Productivity (GPP) and Ecosystem Respiration (Re). Controlling factors of seasonal and diurnal variations of carbon and energy fluxes are analyzed, and land cover impacts on the variation patterns are also studied. Finally, the coupling between the carbon and energy fluxes are analyzed under different atmospheric, boundary stability and land cover conditions.

  9. SSC RIAR is the largest centre of research reactors

    International Nuclear Information System (INIS)

    Kalygin, V.V.

    1997-01-01

    The State Scientific Centre (SSC) ''Research Institute of Atomic Reactors'' (RIAR) is situated 100 km to the south-east from Moscow, in Dimitrovgrad, the Volga Region of the Russian Federation. SSC RIAR is the largest centre of research reactors in Russia. At present there are 5 types of reactor facilities in operation, including two NPP. One of the main tasks the Centre is the investigations on safety increase for power reactors. Broad international connections are available at the Institute. On the basis of the SSC RIAR during 3 years work has been done on the development of the branch training centre (TC) for the training of operation personnel of research and pilot reactors in Russia. (author). 3 tabs

  10. Switzerland's largest wood-pellet factory in Balsthal

    International Nuclear Information System (INIS)

    Stohler, F.

    2004-01-01

    This article describes how a small Swiss electricity utility has broken out of its traditional role in power generation and the distribution of electricity and gone into the production of wood pellets. The pellets, which are made from waste wood (sawdust) available from wood processing companies, are produced on a large scale in one of Europe's largest pellets production facilities. The boom in the use of wood pellets for heating purposes is discussed. The article discusses this unusual approach for a Swiss power utility, which also operates a wood-fired power station and is even involved in an incineration plant for household wastes. The markets being aimed for in Switzerland and in Europe are described, including modern low-energy-consumption housing projects. A further project is described that is to use waste wood available from a large wood processing facility planned in the utility's own region

  11. Opportunities for biodiversity gains under the world's largest reforestation programme

    Science.gov (United States)

    Hua, Fangyuan; Wang, Xiaoyang; Zheng, Xinlei; Fisher, Brendan; Wang, Lin; Zhu, Jianguo; Tang, Ya; Yu, Douglas W.; Wilcove, David S.

    2016-01-01

    Reforestation is a critical means of addressing the environmental and social problems of deforestation. China's Grain-for-Green Program (GFGP) is the world's largest reforestation scheme. Here we provide the first nationwide assessment of the tree composition of GFGP forests and the first combined ecological and economic study aimed at understanding GFGP's biodiversity implications. Across China, GFGP forests are overwhelmingly monocultures or compositionally simple mixed forests. Focusing on birds and bees in Sichuan Province, we find that GFGP reforestation results in modest gains (via mixed forest) and losses (via monocultures) of bird diversity, along with major losses of bee diversity. Moreover, all current modes of GFGP reforestation fall short of restoring biodiversity to levels approximating native forests. However, even within existing modes of reforestation, GFGP can achieve greater biodiversity gains by promoting mixed forests over monocultures; doing so is unlikely to entail major opportunity costs or pose unforeseen economic risks to households. PMID:27598524

  12. SSC RIAR is the largest centre of research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kalygin, V V [State Scientific Centre, Research Inst. of Atomic Reactors (Russian Federation)

    1997-10-01

    The State Scientific Centre (SSC) ``Research Institute of Atomic Reactors`` (RIAR) is situated 100 km to the south-east from Moscow, in Dimitrovgrad, the Volga Region of the Russian Federation. SSC RIAR is the largest centre of research reactors in Russia. At present there are 5 types of reactor facilities in operation, including two NPP. One of the main tasks the Centre is the investigations on safety increase for power reactors. Broad international connections are available at the Institute. On the basis of the SSC RIAR during 3 years work has been done on the development of the branch training centre (TC) for the training of operation personnel of research and pilot reactors in Russia. (author). 3 tabs.

  13. The largest Silurian vertebrate and its palaeoecological implications

    Science.gov (United States)

    Choo, Brian; Zhu, Min; Zhao, Wenjin; Jia, Liaotao; Zhu, You'an

    2014-01-01

    An apparent absence of Silurian fishes more than half-a-metre in length has been viewed as evidence that gnathostomes were restricted in size and diversity prior to the Devonian. Here we describe the largest pre-Devonian vertebrate (Megamastax amblyodus gen. et sp. nov.), a predatory marine osteichthyan from the Silurian Kuanti Formation (late Ludlow, ~423 million years ago) of Yunnan, China, with an estimated length of about 1 meter. The unusual dentition of the new form suggests a durophagous diet which, combined with its large size, indicates a considerable degree of trophic specialisation among early osteichthyans. The lack of large Silurian vertebrates has recently been used as constraint in palaeoatmospheric modelling, with purported lower oxygen levels imposing a physiological size limit. Regardless of the exact causal relationship between oxygen availability and evolutionary success, this finding refutes the assumption that pre-Emsian vertebrates were restricted to small body sizes. PMID:24921626

  14. Largest US oil and gas fields, August 1993

    International Nuclear Information System (INIS)

    1993-01-01

    The Largest US Oil and Gas Fields is a technical report and part of an Energy Information Administration (EIA) series presenting distributions of US crude oil and natural gas resources, developed using field-level data collected by EIA's annual survey of oil and gas proved reserves. The series' objective is to provide useful information beyond that routinely presented in the EIA annual report on crude oil and natural gas reserves. These special reports also will provide oil and gas resource analysts with a fuller understanding of the nature of US crude oil and natural gas occurrence, both at the macro level and with respect to the specific subjects addressed. The series' approach is to integrate EIA's crude oil and natural gas survey data with related data obtained from other authoritative sources, and then to present illustrations and analyses of interest to a broad spectrum of energy information users ranging from the general public to oil and gas industry personnel

  15. The largest glitch observed in the Crab pulsar

    Science.gov (United States)

    Shaw, B.; Lyne, A. G.; Stappers, B. W.; Weltevrede, P.; Bassa, C. G.; Lien, A. Y.; Mickaliger, M. B.; Breton, R. P.; Jordan, C. A.; Keith, M. J.; Krimm, H. A.

    2018-05-01

    We have observed a large glitch in the Crab pulsar (PSR B0531+21). The glitch occurred around MJD 58064 (2017 November 8) when the pulsar underwent an increase in the rotation rate of Δν = 1.530 × 10-5 Hz, corresponding to a fractional increase of Δν/ν = 0.516 × 10-6 making this event the largest glitch ever observed in this source. Due to our high-cadence and long-dwell time observations of the Crab pulsar we are able to partially resolve a fraction of the total spin-up of the star. This delayed spin-up occurred over a timescale of ˜1.7 days and is similar to the behaviour seen in the 1989 and 1996 large Crab pulsar glitches. The spin-down rate also increased at the glitch epoch by Δ \\dot{ν } / \\dot{ν } = 7 × 10^{-3}. In addition to being the largest such event observed in the Crab, the glitch occurred after the longest period of glitch inactivity since at least 1984 and we discuss a possible relationship between glitch size and waiting time. No changes to the shape of the pulse profile were observed near the glitch epoch at 610 MHz or 1520 MHz, nor did we identify any changes in the X-ray flux from the pulsar. The long-term recovery from the glitch continues to progress as \\dot{ν } slowly rises towards pre-glitch values. In line with other large Crab glitches, we expect there to be a persistent change to \\dot{ν }. We continue to monitor the long-term recovery with frequent, high quality observations.

  16. Cheetah paradigm revisited: MHC diversity in the world's largest free-ranging population.

    Science.gov (United States)

    Castro-Prieto, Aines; Wachter, Bettina; Sommer, Simone

    2011-04-01

    For more than two decades, the cheetah (Acinonyx jubatus) has been considered a paradigm of disease vulnerability associated with low genetic diversity, particularly at the immune genes of the major histocompatibility complex (MHC). Cheetahs have been used as a classic example in numerous conservation genetics textbooks as well as in many related scientific publications. However, earlier studies used methods with low resolution to quantify MHC diversity and/or small sample sizes. Furthermore, high disease susceptibility was reported only for captive cheetahs, whereas free-ranging cheetahs show no signs of infectious diseases and a good general health status. We examined whether the diversity at MHC class I and class II-DRB loci in 149 Namibian cheetahs was higher than previously reported using single-strand conformation polymorphism analysis, cloning, and sequencing. MHC genes were examined at the genomic and transcriptomic levels. We detected ten MHC class I and four class II-DRB alleles, of which nine MHC class I and all class II-DRB alleles were expressed. Phylogenetic analyses and individual genotypes suggested that the alleles belong to four MHC class I and three class II-DRB putative loci. Evidence of positive selection was detected in both MHC loci. Our study indicated that the low number of MHC class I alleles previously observed in cheetahs was due to a smaller sample size examined. On the other hand, the low number of MHC class II-DRB alleles previously observed in cheetahs was further confirmed. Compared with other mammalian species including felids, cheetahs showed low levels of MHC diversity, but this does not seem to influence the immunocompetence of free-ranging cheetahs in Namibia and contradicts the previous conclusion that the cheetah is a paradigm species of disease vulnerability.

  17. The Factor Structure, Predictors, and Percentile Norms of the Center for Epidemiologic Studies Depression (CES-D Scale in the Dutch-speaking Adult Population of Belgium

    Directory of Open Access Journals (Sweden)

    Qian Wu

    2016-01-01

    Full Text Available The Center of Epidemiologic Studies Depression Scale (CES-D is a commonly used self-report scale to measure depressive symptoms in the general population. In the present study, the Dutch version of the CES-D was administered to a sample of 837 Dutch-speaking adults of Belgium to examine the factor structure of the scale. Using confirmatory factory analysis (CFA, four first-order models and two second-order models were tested, and the second-order factor model with three pairs of correlated error terms provided the best fit to the data. Second, five socio-demographic variables (age, gender, education level, relation status, and family history of depression were included as covariates to the second-order factor model to explore the associations between background characteristics and the latent factor depression using a multiple indicators and multiple causes (MIMIC approach. Age had a significantly negative effect on depression, but the effect was not substantial. Female gender, lower education level, being single or widowed, and having a family history of depression were found to be significant predictors of higher levels of depression symptomatology. Finally, percentile norms on the CES-D raw scores were provided for subgroups of gender by education level for the general Dutch-speaking adult population of Belgium.

  18. Great Lakes Science Center

    Data.gov (United States)

    Federal Laboratory Consortium — Since 1927, Great Lakes Science Center (GLSC) research has provided critical information for the sound management of Great Lakes fish populations and other important...

  19. Oceans of Opportunity. Harnessing Europe's largest domestic energy resource

    International Nuclear Information System (INIS)

    Fichaux, N.; Wilkes, J.

    2009-09-01

    Europe's offshore wind potential is enormous and able to power Europe seven times over. Over 100 GW of offshore wind projects are already in various stages of planning. If realised, these projects would produce 10% of the EU's electricity whilst avoiding 200 million tonnes of CO2 emissions each year. EWEA has a target of 40 GW of offshore wind in the EU by 2020, implying an average annual market growth of 28% over the coming 12 years. The EU market for onshore wind grew by an average 32% per year in the 12-year period from 1992-2004 - what the wind energy industry has achieved on land can be repeated at sea. EWEA's proposed offshore grid builds on the 11 offshore grids currently operating and 21 offshore grids currently being considered by the grid operators in the Baltic and North Seas to give Europe a truly pan-European electricity super highway. Strong political support and action from Europe's policy-makers will allow a new, multi-billion euro industry to be built. This new industry will deliver thousands of green collar jobs and a new renewable energy economy and establish Europe as world leader in offshore wind power technology. A single European electricity market with large amounts of wind power will bring affordable electricity to consumers, reduce import dependence, cut CO2 emissions and allow Europe to access its largest domestic energy source.

  20. Characterization of the largest effector gene cluster of Ustilago maydis.

    Directory of Open Access Journals (Sweden)

    Thomas Brefort

    2014-07-01

    Full Text Available In the genome of the biotrophic plant pathogen Ustilago maydis, many of the genes coding for secreted protein effectors modulating virulence are arranged in gene clusters. The vast majority of these genes encode novel proteins whose expression is coupled to plant colonization. The largest of these gene clusters, cluster 19A, encodes 24 secreted effectors. Deletion of the entire cluster results in severe attenuation of virulence. Here we present the functional analysis of this genomic region. We show that a 19A deletion mutant behaves like an endophyte, i.e. is still able to colonize plants and complete the infection cycle. However, tumors, the most conspicuous symptoms of maize smut disease, are only rarely formed and fungal biomass in infected tissue is significantly reduced. The generation and analysis of strains carrying sub-deletions identified several genes significantly contributing to tumor formation after seedling infection. Another of the effectors could be linked specifically to anthocyanin induction in the infected tissue. As the individual contributions of these genes to tumor formation were small, we studied the response of maize plants to the whole cluster mutant as well as to several individual mutants by array analysis. This revealed distinct plant responses, demonstrating that the respective effectors have discrete plant targets. We propose that the analysis of plant responses to effector mutant strains that lack a strong virulence phenotype may be a general way to visualize differences in effector function.

  1. El Paso natural gas nearing completion of system's largest expansion

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    El Paso Natural Gas Co.'s largest expansion program in its 64-year history will be completed along its northern system this spring or early summer. According to the company, the three-tiered, $241.5 million expansion program will increase El Paso's gas-transport capacity by 835 MMcfd to 2.5 bcfd of conventional and coal-seam gas from the San Juan basin in northwestern New Mexico. That's enough natural gas, says the company, to supply the needs of a city of more than 800,000 residents. This paper reports that the expansion involves the San Juan Triangle system, the company's northern main line, and the Permian-San Juan crossover line. The company also filed with the Federal Energy Regulatory Commission (FERC) in October 1991 to construct a new $15.2 million compressor station, Rio Vista, south of Bloomfield, N.M. The station would be used to move additional gas to the main line

  2. Largest US oil and gas fields, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-06

    The Largest US Oil and Gas Fields is a technical report and part of an Energy Information Administration (EIA) series presenting distributions of US crude oil and natural gas resources, developed using field-level data collected by EIA`s annual survey of oil and gas proved reserves. The series` objective is to provide useful information beyond that routinely presented in the EIA annual report on crude oil and natural gas reserves. These special reports also will provide oil and gas resource analysts with a fuller understanding of the nature of US crude oil and natural gas occurrence, both at the macro level and with respect to the specific subjects addressed. The series` approach is to integrate EIA`s crude oil and natural gas survey data with related data obtained from other authoritative sources, and then to present illustrations and analyses of interest to a broad spectrum of energy information users ranging from the general public to oil and gas industry personnel.

  3. Phosphorus Loadings to the World's Largest Lakes: Sources and Trends

    Science.gov (United States)

    Fink, Gabriel; Alcamo, Joseph; Flörke, Martina; Reder, Klara

    2018-04-01

    Eutrophication is a major water quality issue in lakes worldwide and is principally caused by the loadings of phosphorus from catchment areas. It follows that to develop strategies to mitigate eutrophication, we must have a good understanding of the amount, sources, and trends of phosphorus pollution. This paper provides the first consistent and harmonious estimates of current phosphorus loadings to the world's largest 100 lakes, along with the sources of these loadings and their trends. These estimates provide a perspective on the extent of lake eutrophication worldwide, as well as potential input to the evaluation and management of eutrophication in these lakes. We take a modeling approach and apply the WorldQual model for these estimates. The advantage of this approach is that it allows us to fill in large gaps in observational data. From the analysis, we find that about 66 of the 100 lakes are located in developing countries and their catchments have a much larger average phosphorus yield than the lake catchments in developed countries (11.1 versus 0.7 kg TP km-2 year-1). Second, the main source of phosphorus to the examined lakes is inorganic fertilizer (47% of total). Third, between 2005-2010 and 1990-1994, phosphorus pollution increased at 50 out of 100 lakes. Sixty percent of lakes with increasing pollution are in developing countries. P pollution changed primarily due to changing P fertilizer use. In conclusion, we show that the risk of P-stimulated eutrophication is higher in developing countries.

  4. LHC : The World's Largest Vacuum Systems being commissioned at CERN

    CERN Document Server

    Jiménez, J M

    2008-01-01

    When it switches on in 2008, the 26.7 km Large Hadron Collider (LHC) at CERN, will have the world's largest vacuum system operating over a wide range of pressures and employing an impressive array of vacuum technologies. This system is composed by 54 km of UHV vacuum for the circulating beams and 50 km of insulation vacuum around the cryogenic magnets and the liquid helium transfer lines. Over the 54 km of UHV beam vacuum, 48 km of this are at cryogenic temperature (1.9 K). The remaining 6 km of beam vacuum containing the insertions for "cleaning" the proton beams, radiofrequency cavities for accelerating the protons as well as beam-monitoring equipment is at ambient temperature and uses non-evaporable getter (NEG) coatings - a vacuum technology that was born and industrialized at CERN. The pumping scheme is completed using 780 ion pumps to remove noble gases and to provide pressure interlocks to the 303 vacuum safety valves. Pressure readings are provided by 170 Bayard-Alpert gauges and 1084 gauges (Pirani a...

  5. When clusters collide: constraints on antimatter on the largest scales

    International Nuclear Information System (INIS)

    Steigman, Gary

    2008-01-01

    Observations have ruled out the presence of significant amounts of antimatter in the Universe on scales ranging from the solar system, to the Galaxy, to groups and clusters of galaxies, and even to distances comparable to the scale of the present horizon. Except for the model-dependent constraints on the largest scales, the most significant upper limits to diffuse antimatter in the Universe are those on the ∼Mpc scale of clusters of galaxies provided by the EGRET upper bounds to annihilation gamma rays from galaxy clusters whose intracluster gas is revealed through its x-ray emission. On the scale of individual clusters of galaxies the upper bounds to the fraction of mixed matter and antimatter for the 55 clusters from a flux-limited x-ray survey range from 5 × 10 −9 to −6 , strongly suggesting that individual clusters of galaxies are made entirely of matter or of antimatter. X-ray and gamma-ray observations of colliding clusters of galaxies, such as the Bullet Cluster, permit these constraints to be extended to even larger scales. If the observations of the Bullet Cluster, where the upper bound to the antimatter fraction is found to be −6 , can be generalized to other colliding clusters of galaxies, cosmologically significant amounts of antimatter will be excluded on scales of order ∼20 Mpc (M∼5×10 15 M sun )

  6. Quantifying the annual fish harvest from South Africa's largest ...

    African Journals Online (AJOL)

    2009-08-19

    Aug 19, 2009 ... The resultant total catch divided by the lakeshore population equated to a per capita fish supply of 11.1 ... ment, tourism development, optimal economic benefit from water, and ... To estimate seasonal catch rates, randomly stratified rov- ing creel ... Ēi is the mean effort on any day during sampling period i.

  7. Genome size analyses of Pucciniales reveal the largest fungal genomes.

    Science.gov (United States)

    Tavares, Sílvia; Ramos, Ana Paula; Pires, Ana Sofia; Azinheira, Helena G; Caldeirinha, Patrícia; Link, Tobias; Abranches, Rita; Silva, Maria do Céu; Voegele, Ralf T; Loureiro, João; Talhinhas, Pedro

    2014-01-01

    Rust fungi (Basidiomycota, Pucciniales) are biotrophic plant pathogens which exhibit diverse complexities in their life cycles and host ranges. The completion of genome sequencing of a few rust fungi has revealed the occurrence of large genomes. Sequencing efforts for other rust fungi have been hampered by uncertainty concerning their genome sizes. Flow cytometry was recently applied to estimate the genome size of a few rust fungi, and confirmed the occurrence of large genomes in this order (averaging 225.3 Mbp, while the average for Basidiomycota was 49.9 Mbp and was 37.7 Mbp for all fungi). In this work, we have used an innovative and simple approach to simultaneously isolate nuclei from the rust and its host plant in order to estimate the genome size of 30 rust species by flow cytometry. Genome sizes varied over 10-fold, from 70 to 893 Mbp, with an average genome size value of 380.2 Mbp. Compared to the genome sizes of over 1800 fungi, Gymnosporangium confusum possesses the largest fungal genome ever reported (893.2 Mbp). Moreover, even the smallest rust genome determined in this study is larger than the vast majority of fungal genomes (94%). The average genome size of the Pucciniales is now of 305.5 Mbp, while the average Basidiomycota genome size has shifted to 70.4 Mbp and the average for all fungi reached 44.2 Mbp. Despite the fact that no correlation could be drawn between the genome sizes, the phylogenomics or the life cycle of rust fungi, it is interesting to note that rusts with Fabaceae hosts present genomes clearly larger than those with Poaceae hosts. Although this study comprises only a small fraction of the more than 7000 rust species described, it seems already evident that the Pucciniales represent a group where genome size expansion could be a common characteristic. This is in sharp contrast to sister taxa, placing this order in a relevant position in fungal genomics research.

  8. Detection rate of prostate cancer following biopsy among the northern Han Chinese population: a single-center retrospective study of 1022 cases.

    Science.gov (United States)

    Jia, Yong; Zhu, Lei-Yi; Xian, Yu-Xin; Sun, Xiao-Qing; Gao, Jian-Gang; Zhang, Xin-Hong; Hou, Si-Chuan; Zhang, Chang-Cun; Liu, Zhao-Xu

    2017-08-29

    Prostate cancer is known to have ethnic and regional differences. The study aimed to clinically evaluate the detection rate of prostate cancer on transrectal ultrasonography (TRUS)-guided prostate biopsy and analyze its characteristics among the northern Han Chinese population at a single center. Between October 2009 and September 2016, a total of 1027 Chinese men, who had undergone TRUS-guided prostate biopsy at Qingdao Municipal Hospital, were retrospectively analyzed. Prostate biopsies were performed in the case of an abnormally elevated serum PSA level, and/or abnormal digital rectal examination (DRE) findings, and/or suspicious prostatic imaging findings. Of the 1022 men enrolled in the analysis, 438 patients (42.8%) were diagnosed with prostate adenocarcinoma histologically. When serum PSA levels were divided into five subgroups (less than 4.0, 4.0 to 10.0, 10.0 to 20.0, 20.0 to 100.0, and ≥ 100.0 ng/ml), the detection rates of prostate cancer were 12.4, 15.9, 34.1, 66.2, and 93.8%, respectively. With serum PSA levels of 4.0 to 10.0 ng/ml, the cancer detection rates for a normal DRE and a suspect DRE finding were 13.5 and 58.2%, respectively. Accordingly, the cancer detection rates for a normal imaging and a suspect imaging finding were 13.5 and 58.2%, respectively. Besides, a large proportion of the patients were in the clinically advanced stage. The present study data reported a relatively higher prostate cancer detection rate of 42.8% and that the majority of the patients presented with clinically advanced prostate cancers within a local clinical urologic practice. An early detection and screening program for prostate cancer is of great need to reduce the burden from this disease among the northern Han Chinese population.

  9. Characterization of the largest relic Eurasian wild grapevine reservoir in Southern Iberian Peninsula

    Energy Technology Data Exchange (ETDEWEB)

    Arroyo-García, R.; Cantos, M.; Lara, M.; López, M.A.; Gallardo, A.; Ocete, C.A.; Pérez, A.; Bánáti, B.; García, J.L.; Ocete, R.

    2016-11-01

    Wild grapevine is becoming a threatened species in the Iberian Peninsula due to human impacts. The aim of this work was to carry out a holistic study for six years of the largest wild grapevine population found up to date in SW Iberian Peninsula. This population has 115 vines. Ampelographic and soil characteristics have been studied. Evaluation of its environment has also been studied by describing the main parasitic species and natural enemies of pests. The ability of this plant material for its micropropagation and storage in slow-growth conditions has been tested. Microvinification resulted in a wine with good acidity and medium color intensity, two interesting characteristics under a warm climatology. Finally, the identification of private alleles in this wild population, absent in other locations from the Northern and Southern Iberian territories, is a very valuable feature and confirms the importance of establishing conservation programs. The population here studied is genetically unique and potentially useful for commercial rootstocks and cultivars breeding that would improve viticulture and enology. (Author)

  10. GIS learning tool for world's largest earthquakes and their causes

    Science.gov (United States)

    Chatterjee, Moumita

    The objective of this thesis is to increase awareness about earthquakes among people, especially young students by showing the five largest and two most predictable earthquake locations in the world and their plate tectonic settings. This is a geographic based interactive tool which could be used for learning about the cause of great earthquakes in the past and the safest places on the earth in order to avoid direct effect of earthquakes. This approach provides an effective way of learning for the students as it is very user friendly and more aligned to the interests of the younger generation. In this tool the user can click on the various points located on the world map which will open a picture and link to the webpage for that point, showing detailed information of the earthquake history of that place including magnitude of quake, year of past quakes and the plate tectonic settings that made this place earthquake prone. Apart from knowing the earthquake related information students will also be able to customize the tool to suit their needs or interests. Students will be able to add/remove layers, measure distance between any two points on the map, select any place on the map and know more information for that place, create a layer from this set to do a detail analysis, run a query, change display settings, etc. At the end of this tool the user has to go through the earthquake safely guidelines in order to be safe during an earthquake. This tool uses Java as programming language and uses Map Objects Java Edition (MOJO) provided by ESRI. This tool is developed for educational purpose and hence its interface has been kept simple and easy to use so that students can gain maximum knowledge through it instead of having a hard time to install it. There are lots of details to explore which can help more about what a GIS based tool is capable of. Only thing needed to run this tool is latest JAVA edition installed in their machine. This approach makes study more fun and

  11. Five key pillars of an analytics center of excellence, which are required to manage populations and transform organizations into the next era of health care.

    Science.gov (United States)

    Reichert, Jim; Furlong, Gerry

    2014-01-01

    Acute care facilities are experiencing fiscal challenges as noted by decreasing admissions and lower reimbursement creating an unsustainable fiscal environment as we move into the next era of health care. This situation necessitates a strategy to move away from acting solely on hunches and instinct to using analytics to become a truly data-driven organization that identifies opportunities within patient populations to improve the quality and efficiency of care across the continuum. A brief overview of knowledge management philosophies will be provided and how it is used to enable organizations to leverage data, information, and knowledge for operational transformation leading to improved outcomes. This article outlines the 5 key pillars of an Analytics Center of Excellence; governance, organizational structure, people, process, and technology, that are foundational to the development of this strategy. While culture is the most important factor to achieve organizational transformation and improved care delivery, it is the 5 pillars of the ACoE that will enable the culture shift necessary to become a truly data-driven organization and thus achieve transformation into the next era of health care.

  12. A longitudinal evaluation of the Center for Epidemiologic Studies-Depression scale (CES-D) in a Rheumatoid Arthritis Population using Rasch Analysis

    Science.gov (United States)

    Covic, Tanya; Pallant, Julie F; Conaghan, Philip G; Tennant, Alan

    2007-01-01

    Background The aim of this study was to test the internal validity of the total Center for Epidemiologic Studies-Depression (CES-D) scale using Rasch analysis in a rheumatoid arthritis (RA) population. Methods CES-D was administered to 157 patients with RA over three time points within a 12 month period. Rasch analysis was applied using RUMM2020 software to assess the overall fit of the model, the response scale used, individual item fit, differential item functioning (DIF) and person separation. Results Pooled data across three time points was shown to fit the Rasch model with removal of seven items from the original 20-item CES-D scale. It was necessary to rescore the response format from four to three categories in order to improve the scale's fit. Two items demonstrated some DIF for age and gender but were retained within the 13-item CES-D scale. A new cut point for depression score of 9 was found to correspond to the original cut point score of 16 in the full CES-D scale. Conclusion This Rasch analysis of the CES-D in a longstanding RA cohort resulted in the construction of a modified 13-item scale with good internal validity. Further validation of the modified scale is recommended particularly in relation to the new cut point for depression. PMID:17629902

  13. A longitudinal evaluation of the Center for Epidemiologic Studies-Depression scale (CES-D in a Rheumatoid Arthritis Population using Rasch Analysis

    Directory of Open Access Journals (Sweden)

    Tennant Alan

    2007-07-01

    Full Text Available Abstract Background The aim of this study was to test the internal validity of the total Center for Epidemiologic Studies-Depression (CES-D scale using Rasch analysis in a rheumatoid arthritis (RA population. Methods CES-D was administered to 157 patients with RA over three time points within a 12 month period. Rasch analysis was applied using RUMM2020 software to assess the overall fit of the model, the response scale used, individual item fit, differential item functioning (DIF and person separation. Results Pooled data across three time points was shown to fit the Rasch model with removal of seven items from the original 20-item CES-D scale. It was necessary to rescore the response format from four to three categories in order to improve the scale's fit. Two items demonstrated some DIF for age and gender but were retained within the 13-item CES-D scale. A new cut point for depression score of 9 was found to correspond to the original cut point score of 16 in the full CES-D scale. Conclusion This Rasch analysis of the CES-D in a longstanding RA cohort resulted in the construction of a modified 13-item scale with good internal validity. Further validation of the modified scale is recommended particularly in relation to the new cut point for depression.

  14. Prevalence of mental disorders in a population requesting health services at a primary health care center and its association with suicidal ideation and perceived disability

    Directory of Open Access Journals (Sweden)

    Mérida R. Rodríguez

    2012-10-01

    Full Text Available Objective: this study’s goal was to determine the most prevalent mental disorders and the impact on the perception of disability and suicidal ideation among the population from a primary health care center in the city of Cali. Methodology: a cross sectional study was conducted on 254 patients who were screened with the prime-md instrument. Descriptive statistics was used in the analysis to determine the most frequent disorders. Similarly, a multiple analysis with logistic and Poisson regressions using robust variance was conducted to determine the influence of mental disorders on disability and suicidal ideation. Results: most patients were female, young, and mature adults. Depression was present in 66.8% of all cases, followed by somatization disorder and anxiety. Half of the patients had had suicidal ideations at some point in their lives, and three out of four patients claimed to suffer from some kind of disability. Upon adjusting for the covariables, depression and anxiety disorders had a strong association with suicidal ideation and perceived disability that was overestimated by the logistic regression. Conclusion: depression and anxiety were the most common disorders and showed a strong association with suicidal ideation and disability. This is why it is necessary to screen for those disorders among adults using primary health care services. Likewise, we suggest considering Poisson regression with robust variance in cross-sectional studies in health services.

  15. Drilling the Bushveld Complex- the world's largest layered mafic intrusion

    Science.gov (United States)

    Ashwal, L. D.; Webb, S. J.; Trumbull, R. B.

    2013-12-01

    The fact that surprising new discoveries can be made in layered mafic intrusions (e.g., subtle 100-150 m cyclicity in apparently homogeneous cumulates over 1000s of m) means that we are still in the first-order characterization phase of understanding these objects. Accordingly, we have secured funding from ICDP for a planning workshop to be held in Johannesburg in early 2014, aimed at scientific drilling of the Bushveld Complex, the world's largest layered mafic intrusion. Science objectives include, but are not limited to: 1. Magma chamber processes & melt evolution. How many melts/magmas/mushes were involved, what were their compositions and how did they interact? What, if anything, is missing from the Complex, and where did it go? Did Bushveld magmatism have an effect upon Earth's atmosphere at 2 Ga? 2. Crust-mantle interactions & origin of Bushveld granitoids. Are Bushveld granites & rhyolites crustal melts, differentiates from the mafic magmas or products of immiscibility? How can the evolved isotopic signatures in the mafic rocks (e.g., epsilon Nd to -8) be understood? 3. Origin of ore deposits. What were the relative roles of gravity settling, magma mixing, immiscibility and hydrothermal fluid transport in producing the PGE, Cr and V deposits? We have identified 3 potential drilling targets representing a total of ~12 km of drill core. Exact locations of drill sites are to be discussed at the workshop. Target A- East-Central Bushveld Complex. We propose 3 overlapping 3 km boreholes that will provide the first roof-to-floor continuous coverage of the Rustenburg Layered Suite. These boreholes will represent a curated, internationally available reference collection of Bushveld material for present and future research. Target B- Southeastern Bushveld Complex. We propose a single borehole of ~2 km depth, collared in Rooiberg felsite, and positioned to intersect the Roof Zone, Upper Zone, Main Zone and floor of the Complex. Amongst other things, this site will

  16. Final Status Survey for the Largest Decommissioning Project on Earth

    International Nuclear Information System (INIS)

    Dubiel, R.W.; Miller, J.; Quayle, D.

    2006-01-01

    To assist the United States Department of Energy's (US DOE's) re-industrialization efforts at its gaseous diffusion site in Oak Ridge, Tennessee, known as the East Tennessee Technology Park (ETTP), the US DOE awarded a 6-year Decontamination and Decommissioning (D and D) contract to BNG America (formerly BNFL Inc.) in 1997. The ETTP 3-Building D and D Project included the removal and disposition of the materials and equipment from the K-33, K-31, and K-29 Gaseous Diffusion Plant buildings. The three buildings comprise more than 4.8 million square feet (446,000 square meters) of floor surface area and more than 350 million pounds (148 million kilograms) of hazardous and radioactively contaminated material, making it the largest nuclear D and D project in progress anywhere in the world. The logistical hurdles involved in a project of this scope and magnitude required an extensive amount of Engineering and Health Physics professionals. In order to accomplish the Final Status Survey (FSS) for a project of this scope, the speed and efficiency of automated survey equipment was essential. Surveys of floors, structural steel and ceilings up to 60 feet (18 meters) were required. The FSS had to be expanded to include additional remediation and surveys due to characterization surveys and assumptions regarding the nature and extent of contamination provided by the US DOE. Survey design and technical bases had to consider highly variable constituents; including uranium from depleted to low enrichment, variable levels of Technetium-99 and transuranic nuclides, which were introduced into the cascade during the 1960's when recycled uranium (RU) from Savannah River was re-enriched at the facility. The RU was transported to unexpected locations from leaks in the cascade by complex building ventilation patterns. The primary survey tool used for the post remediation and FSS was the Surface Contamination Monitor (SCM) and the associated Survey Information Management System (SIMS

  17. Prostate Cancer Screening in Jamaica: Results of the Largest National Screening Clinic Prostate Cancer Screening in Jamaica: Results of the Largest National Screening Clinic

    International Nuclear Information System (INIS)

    Morrison, B. F.; Aiken, W.; Mayhew, R.; Gordon, Y.; Reid, M.

    2016-01-01

    Prostate cancer is highly prevalent in Jamaica and is the leading cause of cancer-related deaths. Our aim was to evaluate the patterns of screening in the largest organized screening clinic in Jamaica at the Jamaica Cancer Society. A retrospective analysis of all men presenting for screening at the Jamaica Cancer Society from 1995 to 2005 was done. All patients had digital rectal examinations (DRE) and prostate specific antigen (PSA) tests done. Results of prostate biopsies were noted. 1117 men of mean age 59.9 ± 8.2 years presented for screening. The median documented PSA was 1.6 ng/mL (maximum of 5170 ng/mL). Most patients presented for only 1 screen. There was a gradual reduction in the mean age of presentation for screening over the period. Prostate biopsies were requested on 11% of screening visits; however, only 59% of these were done. 5.6% of all persons screened were found to have cancer. Of the cancers diagnosed, Gleason 6 adenocarcinoma was the commonest grade and median PSA was 8.9 ng/mL (range 1.5-1059 ng/mL). Older men tend to screen for prostate cancer in Jamaica. However, compliance with regular maintenance visits and requests for confirmatory biopsies are poor. Screening needs intervention in the Jamaican population.

  18. Mauna Loa--history, hazards and risk of living with the world's largest volcano

    Science.gov (United States)

    Trusdell, Frank A.

    2012-01-01

    Mauna Loa on the Island Hawaiʻi is the world’s largest volcano. People residing on its flanks face many hazards that come with living on or near an active volcano, including lava flows, explosive eruptions, volcanic smog, damaging earthquakes, and local tsunami (giant seawaves). The County of Hawaiʻi (Island of Hawaiʻi) is the fastest growing County in the State of Hawaii. Its expanding population and increasing development mean that risk from volcano hazards will continue to grow. U.S. Geological Survey (USGS) scientists at the Hawaiian Volcano Observatory (HVO) closely monitor and study Mauna Loa Volcano to enable timely warning of hazardous activity and help protect lives and property.

  19. Cyanobacterial bloom in the world largest freshwater lake Baikal

    Science.gov (United States)

    Namsaraev, Zorigto; Melnikova, Anna; Ivanov, Vasiliy; Komova, Anastasia; Teslyuk, Anton

    2018-02-01

    Lake Baikal is a UNESCO World Heritage Site and holds 20% of the world’s freshwater reserves. On July 26, 2016, a cyanobacterial bloom of a green colour a few kilometers in size with a bad odor was discovered by local people in the Barguzinsky Bay on the eastern shore of Lake Baikal. Our study showed very high concentration of chlorophyll a (41.7 g/m3) in the sample of bloom. We found that the bloom was dominated by a nitrogen-fixing heterocystous cyanobacteria of the genus Dolichospermum. The mass accumulation of cyanobacteria in the lake water with an extremely high chlorophyll a concentration can be explained by a combination of several factors: the discharge of biologicaly-available nutrients, including phosphorus, into the water of Lake Baikal; low wind speed and weak water mixing; buoyant cyanobacterial cells on the lake surface, which drifted towards the eastern coast, where the maximum concentration of chlorophyll a was recorded. In the center of the Barguzinsky Bay and in the open part of Lake Baikal, according to satellite data, the chlorophyll a concentration is several orders of magnitude lower than at the shoreline.

  20. Health and Prevention Enhancement (H-PEACE): a retrospective, population-based cohort study conducted at the Seoul National University Hospital Gangnam Center, Korea.

    Science.gov (United States)

    Lee, Changhyun; Choe, Eun Kyung; Choi, Ji Min; Hwang, Yunji; Lee, Young; Park, Boram; Chung, Su Jin; Kwak, Min-Sun; Lee, Jong-Eun; Kim, Joo Sung; Park, Sue Kyung; Cho, Sang-Heon

    2018-04-19

    The Health and Prevention Enhancement (H-PEACE) study was designed to investigate the association of diagnostic imaging results, biomarkers and the predisease stage of non-communicable diseases (NCDs), such as malignancies and metabolic diseases, in an average-risk population in Korea. This study enrolled a large-scale retrospective cohort at the Healthcare System Gangnam Center, Seoul National University Hospital, from October 2003 to December 2014. The baseline and follow-up information collected in the predisease stage of NCDs allows for evaluation of an individual's potential NCD risk, which is necessary for establishing personalised prevention strategies. A total of 91 336 health examinees were included in the cohort, and we repeatedly measured and collected information for 50.9% (n=46 484) of the cohort members. All participants completed structured questionnaires (lifestyle, medical history, mini-dietary assessment index, sex-specific variables and psychiatric assessment), doctors' physical examinations, laboratory blood and urine tests and digital chest X-ray imaging. For participants with available data, we also obtained information on specific diagnostic variables using advanced diagnostic tests, including coronary CT for coronary calcium scores, colonoscopy and brain MRI. Furthermore, 17 455 of the participants who provided informed consent and donated blood samples were enrolled into the Gene-environmental interaction and phenotype study, a subcohort of the H-PEACE, from October 2013, and we analysed genome-wide single-nucleotide polymorphism array data for 6579 of these blood samples. The data obtained from this cohort will be used to facilitate advanced and accurate diagnostic techniques related to NCDs while considering various phenotypes. Potential collaborators can access the dataset after receiving approval from our institutional review board. Applications can be submitted on the study homepage (http://en-healthcare.snuh.org/HPEACEstudy).

  1. A first attempt : k-center

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. A first attempt : k-center. Randomly select R= C x k points. expected C points from the “largest cluster”. Consider all C-points subsets of R. (at least one will be “purely” from largest cluster). Centroid of this will approximate cluster centre.

  2. DISCOVERY OF THE LARGEST KNOWN LENSED IMAGES FORMED BY A CRITICALLY CONVERGENT LENSING CLUSTER

    International Nuclear Information System (INIS)

    Zitrin, Adi; Broadhurst, Tom

    2009-01-01

    We identify the largest known lensed images of a single spiral galaxy, lying close to the center of the distant cluster MACS J1149.5+2223 (z = 0.544). These images cover a total area of ≅150 mbox '' and are magnified ≅200 times. Unusually, there is very little image distortion, implying that the central mass distribution is almost uniform over a wide area (r ≅ 200 kpc) with a surface density equal to the critical density for lensing, corresponding to maximal lens magnification. Many fainter multiply lensed galaxies are also uncovered by our model, outlining a very large tangential critical curve, of radius r ≅ 170 kpc, posing a potential challenge for the standard LCDM cosmology. Because of the uniform central mass distribution, a particularly clean measurement of the mass of the brightest cluster galaxy is possible here, for which we infer stars contribute most of the mass within a limiting radius of ≅30 kpc, with a mass-to-light ratio of M/L B ≅ 4.5(M/L) sun . This cluster with its uniform and central mass distribution acts analogously to a regular magnifying glass, converging light without distorting the images, resulting in the most powerful lens yet discovered for accessing the faint high-z universe.

  3. Population, migration and urbanization.

    Science.gov (United States)

    1982-06-01

    Despite recent estimates that natural increase is becoming a more important component of urban growth than rural urban transfer (excess of inmigrants over outmigrants), the share of migration in the total population growth has been consistently increasing in both developed and developing countries. From a demographic perspective, the migration process involves 3 elements: an area of origin which the mover leaves and where he or she is considered an outmigrant; the destination or place of inmigration; and the period over which migration is measured. The 2 basic types of migration are internal and international. Internal migration consists of rural to urban migration, urban to urban migration, rural to rural migration, and urban to rural migration. Among these 4 types of migration various patterns or processes are followed. Migration may be direct when the migrant moves directly from the village to the city and stays there permanently. It can be circular migration, meaning that the migrant moves to the city when it is not planting season and returns to the village when he is needed on the farm. In stage migration the migrant makes a series of moves, each to a city closer to the largest or fastest growing city. Temporary migration may be 1 time or cyclical. The most dominant pattern of internal migration is rural urban. The contribution of migration to urbanization is evident. For example, the rapid urbanization and increase in urban growth from 1960-70 in the Republic of Korea can be attributed to net migration. In Asia the largest component of the population movement consists of individuals and groups moving from 1 rural location to another. Recently, because urban centers could no longer absorb the growing number of migrants from other places, there has been increased interest in the urban to rural population redistribution. This reverse migration also has come about due to slower rates of employment growth in the urban centers and improved economic opportunities

  4. The largest human cognitive performance dataset reveals insights into the effects of lifestyle factors and aging

    Directory of Open Access Journals (Sweden)

    Daniel A Sternberg

    2013-06-01

    Full Text Available Making new breakthroughs in understanding the processes underlying human cognition may depend on the availability of very large datasets that have not historically existed in psychology and neuroscience. Lumosity is a web-based cognitive training platform that has grown to include over 600 million cognitive training task results from over 35 million individuals, comprising the largest existing dataset of human cognitive performance. As part of the Human Cognition Project, Lumosity’s collaborative research program to understand the human mind, Lumos Labs researchers and external research collaborators have begun to explore this dataset in order uncover novel insights about the correlates of cognitive performance. This paper presents two preliminary demonstrations of some of the kinds of questions that can be examined with the dataset. The first example focuses on replicating known findings relating lifestyle factors to baseline cognitive performance in a demographically diverse, healthy population at a much larger scale than has previously been available. The second example examines a question that would likely be very difficult to study in laboratory-based and existing online experimental research approaches: specifically, how learning ability for different types of cognitive tasks changes with age. We hope that these examples will provoke the imagination of researchers who are interested in collaborating to answer fundamental questions about human cognitive performance.

  5. Epidemiological study of hepatitis A, B and C in the largest Afro-Brazilian isolated community.

    Science.gov (United States)

    Matos, Márcia A D; Reis, Nádia Rúbia S; Kozlowski, Aline G; Teles, Sheila A; Motta-Castro, Ana Rita C; Mello, Francisco C A; Gomes, Selma A; Martins, Regina M B

    2009-09-01

    This study was conducted to estimate the prevalence and molecular epidemiological features of viral hepatitis A, B and C in the Kalunga population, which represents the largest Afro-Brazilian isolated community. Among 878 individuals studied, the overall prevalence of anti-hepatitis A virus antibodies was 80.9%, with a significant rise from 44.8% to near 100% between the first and fourth decade of life. Rates for hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen (anti-HBc) of 1.8% and 35.4%, respectively, were found. Increasing age, male gender, illiteracy and history of multiple sexual partners were associated with hepatitis B virus (HBV) infection. An occult HBV infection rate of 1.7% (5/295) was found among anti-HBc-positive individuals. HBV genotype A (subtype Aa) was dominant in this community. Only 5/878 individuals (0.6%) were positive for anti-hepatitis C virus (HCV). HCV RNA was detected in three of them, who were infected with genotype 1 (subtype 1a). These findings point out high, intermediate and low endemicity for hepatitis A, B and C, respectively, in the Kalunga community in Brazil. Circulation of HBV genotype A (subtype Aa) in this Afro-Brazilian isolated community indicates the introduction of this virus during the slave trade from Africa to Brazil.

  6. Dragon's paradise lost: palaeobiogeography, evolution and extinction of the largest-ever terrestrial lizards (Varanidae.

    Directory of Open Access Journals (Sweden)

    Scott A Hocknull

    Full Text Available BACKGROUND: The largest living lizard species, Varanus komodoensis Ouwens 1912, is vulnerable to extinction, being restricted to a few isolated islands in eastern Indonesia, between Java and Australia, where it is the dominant terrestrial carnivore. Understanding how large-bodied varanids responded to past environmental change underpins long-term management of V. komodoensis populations. METHODOLOGY/PRINCIPAL FINDINGS: We reconstruct the palaeobiogeography of Neogene giant varanids and identify a new (unnamed species from the island of Timor. Our data reject the long-held perception that V. komodoensis became a giant because of insular evolution or as a specialist hunter of pygmy Stegodon. Phyletic giantism, coupled with a westward dispersal from mainland Australia, provides the most parsimonious explanation for the palaeodistribution of V. komodoensis and the newly identified species of giant varanid from Timor. Pliocene giant varanid fossils from Australia are morphologically referable to V. komodoensis suggesting an ultimate origin for V. komodoensis on mainland Australia (>3.8 million years ago. Varanus komodoensis body size has remained stable over the last 900,000 years (ka on Flores, a time marked by major faunal turnovers, extinction of the island's megafauna, the arrival of early hominids by 880 ka, co-existence with Homo floresiensis, and the arrival of modern humans by 10 ka. Within the last 2000 years their populations have contracted severely. CONCLUSIONS/SIGNIFICANCE: Giant varanids were once a ubiquitous part of Subcontinental Eurasian and Australasian faunas during the Neogene. Extinction played a pivotal role in the reduction of their ranges and diversity throughout the late Quaternary, leaving only V. komodoensis as an isolated long-term survivor. The events over the last two millennia now threaten its future survival.

  7. Comparison of the clinical and cognitive features of genetically positive ALS patients from the largest tertiary center in Serbia.

    Science.gov (United States)

    Marjanović, Ivan V; Selak-Djokić, Biljana; Perić, Stojan; Janković, Milena; Arsenijević, Vladimir; Basta, Ivana; Lavrnić, Dragana; Stefanova, Elka; Stević, Zorica

    2017-06-01

    Discovering novel mutations in C9orf72, FUS, ANG, and TDP-43 genes in ALS patients arises necessities for better clinical characterizations of these subjects. The aim is to determine clinical and cognitive profile of genetically positive Serbian ALS patients. 241 ALS patients were included in the study (17 familiar and 224 apparently sporadic). The following genes were analyzed: SOD1, C9orf72, ANG, FUS, and TDP-43. An extensive battery of classic neuropsychological tests was used in 27 ALS patients (22 SOD1 positive and 5 SOD1 negative) and 82 healthy controls (HCs). Overall 37 (15.4%) of 241 ALS patients carried mutations in tested genes-among 17 familiar ALS patients 16 (94.1%) were positive and among 224 apparently sporadic 21 (9.4%) had causative mutation. Mutations in SOD1 gene were the most common, representing 27 (73.0%) of all genetically positive ALS patients. The main clinical characteristics of SOD1 positive patients were: spinal onset in lower extremities, common sphincter and sensitive disturbances, and dysexecutive syndrome. Within SOD1 positive patients, we noticed somewhat earlier onset in patients with A145G, sensory and sphincter disturbances were dominant in patients with L144F, while D90A patients had significant sensory involvement. SOD1 negative group consisted of ten (27.0%) patients (six C9orf72, two ANG, one TDP-43, and one patient baring triple FUS, C9orf72 expansion, and ANG variants). Bulbar involvement and more extensive neuropsychological impairment (including executive, visuospatial, and memory difficulties) were the main features of SOD1 negative cohort. Our results suggest that meaningful clinical suspicion of certain ALS genotype might be made based on thorough clinical evaluation of patients.

  8. Oak habitat recovery on California's largest islands: Scenarios for the role of corvid seed dispersal

    Science.gov (United States)

    Pesendorfer, Mario B.; Baker, Christopher M.; Stringer, Martin; McDonald-Madden, Eve; Bode, Michael; McEachern, A. Kathryn; Morrison, Scott A.; Sillett, T. Scott

    2018-01-01

    Seed dispersal by birds is central to the passive restoration of many tree communities. Reintroduction of extinct seed dispersers can therefore restore degraded forests and woodlands. To test this, we constructed a spatially explicit simulation model, parameterized with field data, to consider the effect of different seed dispersal scenarios on the extent of oak populations. We applied the model to two islands in California's Channel Islands National Park (USA), one of which has lost a key seed disperser.We used an ensemble modelling approach to simulate island scrub oak (Quercus pacifica) demography. The model was developed and trained to recreate known population changes over a 20-year period on 250-km2 Santa Cruz Island, and incorporated acorn dispersal by island scrub-jays (Aphelocoma insularis), deer mice (Peromyscus maniculatus) and gravity, as well as seed predation. We applied the trained model to 215-km2 Santa Rosa Island to examine how reintroducing island scrub-jays would affect the rate and pattern of oak population expansion. Oak habitat on Santa Rosa Island has been greatly reduced from its historical extent due to past grazing by introduced ungulates, the last of which were removed by 2011.Our simulation model predicts that a seed dispersal scenario including island scrub-jays would increase the extent of the island scrub oak population on Santa Rosa Island by 281% over 100 years, and by 544% over 200 years. Scenarios without jays would result in little expansion. Simulated long-distance seed dispersal by jays also facilitates establishment of discontinuous patches of oaks, and increases their elevational distribution.Synthesis and applications. Scenario planning provides powerful decision support for conservation managers. We used ensemble modelling of plant demographic and seed dispersal processes to investigate whether the reintroduction of seed dispersers could provide cost-effective means of achieving broader ecosystem restoration goals on

  9. ASSESSMENT OF INHALATION EXPOSURES AND POTENTIAL HEALTH RISKS TO THE GENERAL POPULATION THAT RESULTED FROM THE COLLAPSE OF THE WORLD TRADE CENTER TOWERS

    Science.gov (United States)

    In the days following the collapse of the World Trade Center (WTC) towers on September 11, 2001 (9/11), the U.S. Environmental Protection Agency (EPA) initiated numerous air monitoring activities to better understand the ongoing impact of emissions from that disaster. Using these...

  10. First Experience from the World Largest fully commercial Solar Heating Plant

    DEFF Research Database (Denmark)

    Heller, Alfred; Furbo, Simon

    1997-01-01

    The first experience from the largest solar heating plant in the world is given. The plant is situated in Marstal and is has a total area of 8000 square m.......The first experience from the largest solar heating plant in the world is given. The plant is situated in Marstal and is has a total area of 8000 square m....

  11. Revisiting the phylogeny of Ocellularieae, the second largest tribe within Graphidaceae (lichenized Ascomycota: Ostropales)

    Science.gov (United States)

    Ekaphan Kraichak; Sittiporn Parnmen; Robert Lücking; Eimy Rivas Plata; Andre Aptroot; Marcela E.S. Caceres; Damien Ertz; Armin Mangold; Joel A. Mercado-Diaz; Khwanruan Papong; Dries Van der Broeck; Gothamie Weerakoon; H. Thorsten. Lumbsch; NO-VALUE

    2014-01-01

    We present an updated 3-locus molecular phylogeny of tribe Ocellularieae, the second largest tribe within subfamily Graphidoideae in the Graphidaceae. Adding 165 newly generated sequences from the mitochondrial small subunit rDNA (mtSSU), the nuclear large subunit rDNA (nuLSU), and the second largest subunit of the DNA-directed RNA polymerase II (RPB2), we currently...

  12. Complete Genome Sequence of the Largest Known Flavi-Like Virus, Diaphorina citri flavi-like virus, a Novel Virus of the Asian Citrus Psyllid, Diaphorina citri

    OpenAIRE

    Matsumura, Emilyn E.; Nerva, Luca; Nigg, Jared C.; Falk, Bryce W.; Nouri, Shahideh

    2016-01-01

    A novel flavi-like virus tentatively named Diaphorina citri flavi-like virus (DcFLV) was identified in field populations of Diaphorina citri through small RNA and transcriptome sequencing followed by reverse transcription (RT)-PCR. We report here the complete nucleotide sequence and genome organization of DcFLV, the largest flavi-like virus identified to date.

  13. [State of the world population, 1986].

    Science.gov (United States)

    1987-01-01

    The majority of the world population will soon reside in urban areas. At present, over 40% of the world's people are urban, and 50% will be urban soon after the year 2000. The proportion urban in developed countries has exceeded 50% since the mid-20th century, and in developing countries this level will be reached in the 1st quarter of the next century. Developing countries in Asia and Africa have less than 30% of their population urban. While over 70% of Latin America's population is urban. Within the next 50 years, the predominantly rural character of the developing countries will disappear forever. Currently the majority of the world's urban population lives in developing countries. In 1970, 695 million urban dwellers were in developed countries vs. 666 million in developing countries, but by 1985, there were only 849 million urban dwellers in developed countries vs. 1164 million in developing countries. By the year 2025, there will be nearly 4 times as many urban dwellers in developing countries. An increasing proportion of the urban population will reside in the largest cities. Around 2025, almost 30% of the urban population in developing countries will live in cities of over 4 million. Around 2000 there will be 5 cities of 15 million or more, 3 of them in developing countries. The proportion of the 20 largest cities in developing countries will increase from 9 in 1970 to 16 in 2000. The close relationship between city size and economic development that existed until the recent past is disappearing. It is possible that the very largest cities will no longer be at the center of international political and economic networks. Many developing countries will have to develop plans for cities of sizes never imagined in the developed countries of today. High rates of population increase in the developing countries are an inseparable aspect of their urbanization. Growth of the urban population in developing countries will continue to be rapid until well into the 21st

  14. Solar energy potential of the largest buildings in the United States

    Science.gov (United States)

    Wence, E. R.; Grodsky, S.; Hernandez, R. R.

    2017-12-01

    Sustainable pathways of land use for energy are necessary to mitigate climate change and limit conversion of finite land resources needed for conservation and food production. Large, commercial buildings (LCBs) are increasing in size and number throughout the United States (US) and may serve as suitable recipient environments for photovoltaic (PV) solar energy infrastructure that may support a low carbon, low land footprint energy transition. In this study, we identified, characterized, and evaluated the technical potential of the largest, commercial building rooftops (i.e., exceeding 110,000 m2) and their associated parking lots in the US for PV solar energy systems using Aurora, a cloud-based solar optimization platform. We also performed a case study of building-specific electricity generation: electricity consumption balance. Further, we quantified the environmental co-benefit of land sparing and associated avoided emissions (t-CO2-eq) conferred under the counterfactual scenario that solar development would otherwise proceed as a ground-mounted, utility-scale PV installation of equal nominal capacity. We identified and mapped 37 LCBs (by rooftop area) across 18 states in the US, spanning from as far north as the state of Minnesota to as far south as Florida. Rooftop footprints range from 427,297 to 113,689 m2 and have a cumulative surface area of 99.8 million ft2. We characterize the LCBs as either: distribution/warehouse, factory, shopping center, or administrative office/facility. Three of the 37 LCBs currently support rooftop PV and the numbers of associated, detached buildings number up to 38. This study elucidates the extent to which LCBs and their respective parking lots can serve as suitable sites for PV solar energy generation. Lastly, this study demonstrates research-based applications of the Aurora energy modeling platform and informs decision-making focused on redirecting energy development towards human-modified landscapes to prioritize land use for

  15. Lessons Learned in Deploying the World s Largest Scale Lustre File System

    Energy Technology Data Exchange (ETDEWEB)

    Dillow, David A [ORNL; Fuller, Douglas [ORNL; Wang, Feiyi [ORNL; Oral, H Sarp [ORNL; Zhang, Zhe [ORNL; Hill, Jason J [ORNL; Shipman, Galen M [ORNL

    2010-01-01

    The Spider system at the Oak Ridge National Laboratory's Leadership Computing Facility (OLCF) is the world's largest scale Lustre parallel file system. Envisioned as a shared parallel file system capable of delivering both the bandwidth and capacity requirements of the OLCF's diverse computational environment, the project had a number of ambitious goals. To support the workloads of the OLCF's diverse computational platforms, the aggregate performance and storage capacity of Spider exceed that of our previously deployed systems by a factor of 6x - 240 GB/sec, and 17x - 10 Petabytes, respectively. Furthermore, Spider supports over 26,000 clients concurrently accessing the file system, which exceeds our previously deployed systems by nearly 4x. In addition to these scalability challenges, moving to a center-wide shared file system required dramatically improved resiliency and fault-tolerance mechanisms. This paper details our efforts in designing, deploying, and operating Spider. Through a phased approach of research and development, prototyping, deployment, and transition to operations, this work has resulted in a number of insights into large-scale parallel file system architectures, from both the design and the operational perspectives. We present in this paper our solutions to issues such as network congestion, performance baselining and evaluation, file system journaling overheads, and high availability in a system with tens of thousands of components. We also discuss areas of continued challenges, such as stressed metadata performance and the need for file system quality of service alongside with our efforts to address them. Finally, operational aspects of managing a system of this scale are discussed along with real-world data and observations.

  16. The Adolescent "Expanded Medical Home": School-Based Health Centers Partner with a Primary Care Clinic to Improve Population Health and Mitigate Social Determinants of Health.

    Science.gov (United States)

    Riley, Margaret; Laurie, Anna R; Plegue, Melissa A; Richarson, Caroline R

    2016-01-01

    Access to high-quality health care is a crucial social determinant of health. We describe the implementation of an "expanded medical home" partnering a primary care practice (the Ypsilanti Health Center [YHC]) with local school-based health centers (the Regional Alliance for Healthy Schools [RAHS]), and to assess whether this model improves access to and quality of care for shared patients. Using the Consolidated Framework for Implementation Research, we define the steps in, barriers to, and facilitating factors in implementing the expanded medical home model. Visits and quality measures were assessed for patients seen by YHC only versus YHC/RAHS at baseline and during the intervention. At baseline, patients seen at YHC/RAHS had higher compliance with most quality metrics compared with those seen at YHC only. The proportion of shared patients significantly increased because of the intervention (P partnership between primary care physicians and school-based health centers increases the number of shared high-risk adolescent patients. Shared patients have improved compliance with quality measures, which may lead to long-term improved health equity. © Copyright 2016 by the American Board of Family Medicine.

  17. Development of a tool to measure person-centered maternity care in developing settings: validation in a rural and urban Kenyan population.

    Science.gov (United States)

    Afulani, Patience A; Diamond-Smith, Nadia; Golub, Ginger; Sudhinaraset, May

    2017-09-22

    Person-centered reproductive health care is recognized as critical to improving reproductive health outcomes. Yet, little research exists on how to operationalize it. We extend the literature in this area by developing and validating a tool to measure person-centered maternity care. We describe the process of developing the tool and present the results of psychometric analyses to assess its validity and reliability in a rural and urban setting in Kenya. We followed standard procedures for scale development. First, we reviewed the literature to define our construct and identify domains, and developed items to measure each domain. Next, we conducted expert reviews to assess content validity; and cognitive interviews with potential respondents to assess clarity, appropriateness, and relevance of the questions. The questions were then refined and administered in surveys; and survey results used to assess construct and criterion validity and reliability. The exploratory factor analysis yielded one dominant factor in both the rural and urban settings. Three factors with eigenvalues greater than one were identified for the rural sample and four factors identified for the urban sample. Thirty of the 38 items administered in the survey were retained based on the factors loadings and correlation between the items. Twenty-five items load very well onto a single factor in both the rural and urban sample, with five items loading well in either the rural or urban sample, but not in both samples. These 30 items also load on three sub-scales that we created to measure dignified and respectful care, communication and autonomy, and supportive care. The Chronbach alpha for the main scale is greater than 0.8 in both samples, and that for the sub-scales are between 0.6 and 0.8. The main scale and sub-scales are correlated with global measures of satisfaction with maternity services, suggesting criterion validity. We present a 30-item scale with three sub-scales to measure person-centered

  18. Solomon Islands largest hawksbill turtle rookery shows signs of recovery after 150 years of excessive exploitation.

    Directory of Open Access Journals (Sweden)

    Richard J Hamilton

    Full Text Available The largest rookery for hawksbill turtles in the oceanic South Pacific is the Arnavon Islands, which are located in the Manning Strait between Isabel and Choiseul Province, Solomon Islands. The history of this rookery is one of overexploitation, conflict and violence. Throughout the 1800s Roviana headhunters from New Georgia repeatedly raided the Manning Strait to collect hawksbill shell which they traded with European whalers. By the 1970s the Arnavons hawksbill population was in severe decline and the national government intervened, declaring the Arnavons a sanctuary in 1976. But this government led initiative was short lived, with traditional owners burning down the government infrastructure and resuming intensive harvesting in 1982. In 1991 routine beach monitoring and turtle tagging commenced at the Arnavons along with extensive community consultations regarding the islands' future, and in 1995 the Arnavon Community Marine Conservation Area (ACMCA was established. Around the same time national legislation banning the sale of all turtle products was passed. This paper represents the first analysis of data from 4536 beach surveys and 845 individual turtle tagging histories obtained from the Arnavons between 1991-2012. Our results and the results of others, reveal that many of the hawksbill turtles that nest at the ACMCA forage in distant Australian waters, and that nesting on the Arnavons occurs throughout the year with peak nesting activity coinciding with the austral winter. Our results also provide the first known evidence of recovery for a western pacific hawksbill rookery, with the number of nests laid at the ACMCA and the remigration rates of turtles doubling since the establishment of the ACMCA in 1995. The Arnavons case study provides an example of how changes in policy, inclusive community-based management and long term commitment can turn the tide for one of the most charismatic and endangered species on our planet.

  19. Respiratory infections in elderly people: Viral role in a resident population of elderly care centers in Lisbon, winter 2013–2014

    Directory of Open Access Journals (Sweden)

    Maria-Jesus Chasqueira

    2018-04-01

    Full Text Available Objective: The aim of this study was to analyze the etiology and clinical consequences of viral respiratory infections in 18 elderly care centers (ECC in Lisbon, which housed a total of 1022 residents. Methods: Nasopharyngeal swabs were collected whenever an elderly had symptoms of acute respiratory infections (ARI. PCR and RT-PCR were performed for influenza A/B, human parainfluenza virus 1–4, adenovirus, human metapneumovirus (HMPV, respiratory syncytial virus (RSV, rhinovirus, enterovirus, human coronavirus and human Bocavirus (HBoV. Array cards for atypical bacteria were also used in severe cases. Results: In total, 188 episodes of ARI were reported, being rhinovirus the most frequently detected (n = 53, followed by influenza A(H3 (n = 19 and HBoV (n = 14. Severe infections were reported in 19 patients, 11 of which were fatal, Legionela pneumophila, rhinovirus, HMPV and RSV associated with these fatalities. Nine influenza strains were analyzed, all antigenically dissimilar from vaccine strain 2013/14. “Age”, “HMPV” and “Respiratory disease” showed an association with severe infection. Conclusions: In this study an etiologic agent could be found in 60% of the acute respiratory episodes. These data provides information about the circulating viruses in ECC and highlights the importance of searching both viruses and atypical bacteria in severe ARI. Keywords: Elderly, Respiratory infections, Respiratory viruses, Legionella pneumophila, Elderly care centers, Real time PCR

  20. A marine heatwave drives massive losses from the world’s largest seagrass carbon stocks

    KAUST Repository

    Arias-Ortiz, Ariane; Serrano, Oscar; Masqué , Pere; Lavery, P. S.; Mueller, U.; Kendrick, G. A.; Rozaimi, M.; Esteban, A.; Fourqurean, J. W.; Marbà , N.; Mateo, M. A.; Murray, K.; Rule, M. J.; Duarte, Carlos M.

    2018-01-01

    Seagrass ecosystems contain globally significant organic carbon (C) stocks. However, climate change and increasing frequency of extreme events threaten their preservation. Shark Bay, Western Australia, has the largest C stock reported for a seagrass

  1. Lagisza, world's largest CFB boiler, begins commercial operation

    Energy Technology Data Exchange (ETDEWEB)

    Nuortimo, K. [Foster Wheeler, Varkaus (Finland)

    2010-04-15

    Early operating experience with the Lagisza circulating fluidised bed (CFB) boiler in Poland - the world's largest such boiler to date, and also the first one with supercritical steam conditions - has been positive. 3 figs., 4 tabs.

  2. Analytic approximation to the largest eigenvalue distribution of a white Wishart matrix

    CSIR Research Space (South Africa)

    Vlok, JD

    2012-08-14

    Full Text Available offers largely simplified computation and provides statistics such as the mean value and region of support of the largest eigenvalue distribution. Numeric results from the literature are compared with the approximation and Monte Carlo simulation results...

  3. Rewriting the Landform History of One of Africa's Three Largest Basins

    Science.gov (United States)

    Wilkinson, Justin

    2014-01-01

    The Kalahari Basin in southern Africa - one of the largest basins in Africa, along with the Congo and Chad basins - has attracted attention since David Livingstone traveled through the area in the 1840s. It is a semiarid desert with a large freshwater swampland known as the Okavango Swamp (150 km radius). This prominent megafan (a fan with radii >100 km), with its fingers of dark green forests projecting into the dun colors of the dunes of the Kalahari semi-desert, has been well photographed by astronauts over the years. The study area in the northern Kalahari basin is centered on the Okavango megafan of northwest Botswana, whose swampland has become well known as an African wildlife preserve of importance to biology and tourism alike. The Okavango River is unusual because it has deposited not one but two megafans along its course: the Okavango megafan and the Cubango megafan. The Okavango megafan is one of only three well-known megafans in Africa. Megafans on Earth were once thought to be rare, but recent research has documented 68 in Africa alone. Eleven megafans, plus three more candidates, have been documented in the area immediately surrounding the Okavango feature. These 11 megafans occupy the flattest and smoothest terrains adjacent to the neighboring upland and stand out as the darkest areas in the roughness map of the area. Megafan terrains occupy at least 200,000 sq km of the study area. The roughness map shown is based on an algorithm used first on Mars to quantify topographic roughness. Research of Earth's flattest terrains is just beginning with the aid of such maps, and it appears that these terrains are analogous to the flattest regions of Mars. Implications: 1. The variability in depositional style in each subbasin may apply Africa-wide: rift megafan length is dominated by rift width, whereas Owambo subbasin megafans are probably controlled by upland basin size; Zambezi subbasin megafans appear more like foreland basin types, with the position of

  4. A multi-center randomized controlled trial to compare a self-ligating bracket with a conventional bracket in a UK population: Part 1: Treatment efficiency.

    Science.gov (United States)

    O'Dywer, Lian; Littlewood, Simon J; Rahman, Shahla; Spencer, R James; Barber, Sophy K; Russell, Joanne S

    2016-01-01

    To use a two-arm parallel trial to compare treatment efficiency between a self-ligating and a conventional preadjusted edgewise appliance system. A prospective multi-center randomized controlled clinical trial was conducted in three hospital orthodontic departments. Subjects were randomly allocated to receive treatment with either a self-ligating (3M SmartClip) or conventional (3M Victory) preadjusted edgewise appliance bracket system using a computer-generated random sequence concealed in opaque envelopes, with stratification for operator and center. Two operators followed a standardized protocol regarding bracket bonding procedure and archwire sequence. Efficiency of each ligation system was assessed by comparing the duration of treatment (months), total number of appointments (scheduled and emergency visits), and number of bracket bond failures. One hundred thirty-eight subjects (mean age 14 years 11 months) were enrolled in the study, of which 135 subjects (97.8%) completed treatment. The mean treatment time and number of visits were 25.12 months and 19.97 visits in the SmartClip group and 25.80 months and 20.37 visits in the Victory group. The overall bond failure rate was 6.6% for the SmartClip and 7.2% for Victory, with a similar debond distribution between the two appliances. No significant differences were found between the bracket systems in any of the outcome measures. No serious harm was observed from either bracket system. There was no clinically significant difference in treatment efficiency between treatment with a self-ligating bracket system and a conventional ligation system.

  5. Nuclear Energy Center Site Survey, 1975. Executive summary

    International Nuclear Information System (INIS)

    1976-01-01

    The Nuclear Energy Center Site Survey is a study of a potential alternative siting approach for nuclear power and fuel-cycle facilities, an approach that would cluster sizable groups of such facilities on a relatively small number of sites. The largest aggregation of reactors on a single site being planned today is four, and this quad is assumed (for comparative study purposes) to be the typical dispersed site by the year 2000. Three basic types of nuclear energy centers are considered: power-plant centers, consisting of 10 to 40 nuclear electric generating units of 1200-megawatt electric capacity each; fuel-cycle centers, consisting of fuel reprocessing plants, mixed-oxide fuel fabrication facilities, and radioactive waste management facilities; and combined centers, containing both power plants and fuel-cycle facilities. The results of the general site-location screening efforts are shown on a United States map that shows the locations of large areas identified as likely to contain suitable candidate sites for power NECs, on the basis of four coarse screening criteria: water resources, seismic activity, population density, and statutory excluded lands

  6. Populating a Control Point Database: A cooperative effort between the USGS, Grand Canyon Monitoring and Research Center and the Grand Canyon Youth Organization

    Science.gov (United States)

    Brown, K. M.; Fritzinger, C.; Wharton, E.

    2004-12-01

    The Grand Canyon Monitoring and Research Center measures the effects of Glen Canyon Dam operations on the resources along the Colorado River from Glen Canyon Dam to Lake Mead in support of the Grand Canyon Adaptive Management Program. Control points are integral for geo-referencing the myriad of data collected in the Grand Canyon including aerial photography, topographic and bathymetric data used for classification and change-detection analysis of physical, biologic and cultural resources. The survey department has compiled a list of 870 control points installed by various organizations needing to establish a consistent reference for data collected at field sites along the 240 mile stretch of Colorado River in the Grand Canyon. This list is the foundation for the Control Point Database established primarily for researchers, to locate control points and independently geo-reference collected field data. The database has the potential to be a valuable mapping tool for assisting researchers to easily locate a control point and reduce the occurrance of unknowingly installing new control points within close proximity of an existing control point. The database is missing photographs and accurate site description information. Current site descriptions do not accurately define the location of the point but refer to the project that used the point, or some other interesting fact associated with the point. The Grand Canyon Monitoring and Research Center (GCMRC) resolved this problem by turning the data collection effort into an educational exercise for the participants of the Grand Canyon Youth organization. Grand Canyon Youth is a non-profit organization providing experiential education for middle and high school aged youth. GCMRC and the Grand Canyon Youth formed a partnership where GCMRC provided the logistical support, equipment, and training to conduct the field work, and the Grand Canyon Youth provided the time and personnel to complete the field work. Two data

  7. A Fast-Track Referral System for Skin Lesions Suspicious of Melanoma: Population-Based Cross-Sectional Study from a Plastic Surgery Center

    Directory of Open Access Journals (Sweden)

    Reem Dina Jarjis

    2016-01-01

    Full Text Available Introduction. To minimize delay between presentation, diagnosis, and treatment of cutaneous melanoma (CM, a national fast-track referral system (FTRS was implemented in Denmark. The aim of this study was to analyze the referral patterns to our department of skin lesions suspicious of melanoma in the FTRS. Methods. Patients referred to the Department of Plastic Surgery and Breast Surgery in Zealand University Hospital were registered prospectively over a 1-year period in 2014. A cross-sectional study was performed analyzing referral patterns, including patient and tumor characteristics. Results. A total of 556 patients were registered as referred to the center in the FTRS for skin lesions suspicious of melanoma. Among these, a total of 312 patients (56.1% were diagnosed with CM. Additionally, 41 (7.4% of the referred patients were diagnosed with in situ melanoma. Conclusion. In total, 353 (63.5% patients had a malignant or premalignant melanocytic skin lesion. When only considering patients who where referred without a biopsy, the diagnostic accuracy for GPs and dermatologists was 29% and 45%, respectively. We suggest that efforts of adequate training for the referring physicians in diagnosing melanocytic skin lesions will increase diagnostic accuracy, leading to larger capacity in secondary care for the required treatment of malignant skin lesions.

  8. Chemotaxis in densely populated tissue determines germinal center anatomy and cell motility: a new paradigm for the development of complex tissues.

    Directory of Open Access Journals (Sweden)

    Jared B Hawkins

    Full Text Available Germinal centers (GCs are complex dynamic structures that form within lymph nodes as an essential process in the humoral immune response. They represent a paradigm for studying the regulation of cell movement in the development of complex anatomical structures. We have developed a simulation of a modified cyclic re-entry model of GC dynamics which successfully employs chemotaxis to recapitulate the anatomy of the primary follicle and the development of a mature GC, including correctly structured mantle, dark and light zones. We then show that correct single cell movement dynamics (including persistent random walk and inter-zonal crossing arise from this simulation as purely emergent properties. The major insight of our study is that chemotaxis can only achieve this when constrained by the known biological properties that cells are incompressible, exist in a densely packed environment, and must therefore compete for space. It is this interplay of chemotaxis and competition for limited space that generates all the complex and biologically accurate behaviors described here. Thus, from a single simple mechanism that is well documented in the biological literature, we can explain both higher level structure and single cell movement behaviors. To our knowledge this is the first GC model that is able to recapitulate both correctly detailed anatomy and single cell movement. This mechanism may have wide application for modeling other biological systems where cells undergo complex patterns of movement to produce defined anatomical structures with sharp tissue boundaries.

  9. Chemotaxis in densely populated tissue determines germinal center anatomy and cell motility: a new paradigm for the development of complex tissues.

    Science.gov (United States)

    Hawkins, Jared B; Jones, Mark T; Plassmann, Paul E; Thorley-Lawson, David A

    2011-01-01

    Germinal centers (GCs) are complex dynamic structures that form within lymph nodes as an essential process in the humoral immune response. They represent a paradigm for studying the regulation of cell movement in the development of complex anatomical structures. We have developed a simulation of a modified cyclic re-entry model of GC dynamics which successfully employs chemotaxis to recapitulate the anatomy of the primary follicle and the development of a mature GC, including correctly structured mantle, dark and light zones. We then show that correct single cell movement dynamics (including persistent random walk and inter-zonal crossing) arise from this simulation as purely emergent properties. The major insight of our study is that chemotaxis can only achieve this when constrained by the known biological properties that cells are incompressible, exist in a densely packed environment, and must therefore compete for space. It is this interplay of chemotaxis and competition for limited space that generates all the complex and biologically accurate behaviors described here. Thus, from a single simple mechanism that is well documented in the biological literature, we can explain both higher level structure and single cell movement behaviors. To our knowledge this is the first GC model that is able to recapitulate both correctly detailed anatomy and single cell movement. This mechanism may have wide application for modeling other biological systems where cells undergo complex patterns of movement to produce defined anatomical structures with sharp tissue boundaries.

  10. The Multivariate Largest Lyapunov Exponent as an Age-Related Metric of Quiet Standing Balance

    Directory of Open Access Journals (Sweden)

    Kun Liu

    2015-01-01

    Full Text Available The largest Lyapunov exponent has been researched as a metric of the balance ability during human quiet standing. However, the sensitivity and accuracy of this measurement method are not good enough for clinical use. The present research proposes a metric of the human body’s standing balance ability based on the multivariate largest Lyapunov exponent which can quantify the human standing balance. The dynamic multivariate time series of ankle, knee, and hip were measured by multiple electrical goniometers. Thirty-six normal people of different ages participated in the test. With acquired data, the multivariate largest Lyapunov exponent was calculated. Finally, the results of the proposed approach were analysed and compared with the traditional method, for which the largest Lyapunov exponent and power spectral density from the centre of pressure were also calculated. The following conclusions can be obtained. The multivariate largest Lyapunov exponent has a higher degree of differentiation in differentiating balance in eyes-closed conditions. The MLLE value reflects the overall coordination between multisegment movements. Individuals of different ages can be distinguished by their MLLE values. The standing stability of human is reduced with the increment of age.

  11. Identifying the node spreading influence with largest k-core values

    International Nuclear Information System (INIS)

    Lin, Jian-Hong; Guo, Qiang; Dong, Wen-Zhao; Tang, Li-Ying; Liu, Jian-Guo

    2014-01-01

    Identifying the nodes with largest spreading influence of complex networks is one of the most promising domains. By taking into account the neighbors' k-core values, we present an improved neighbors' k-core (INK) method which is the sum of the neighbors' k-core values with a tunable parameter α to evaluate the node spreading influence with largest k-core values. Comparing with the Susceptible–Infected–Recovered (SIR) results for four real networks, the INK method could identify the node spreading influence with largest k-core values more accurately than the ones generated by the degree k, closeness C, betweenness B and coreness centrality method. - Highlights: • We present an improved neighbors' k-core (INK) method to evaluate the node spreading influence with largest k-core values. • The INK method could identify the node spreading influence with largest k-core values more accurately. • Kendall's tau τ of INK method with α=1 are highly identical to rank the node influence

  12. CH4 emissions from European Major Population Centers: Results from aircraft-borne CH4 in-situ observations during EMeRGe-Europe campaign 2017

    Science.gov (United States)

    Roiger, A.; Klausner, T.; Schlager, H.; Ziereis, H.; Huntrieser, H.; Baumann, R.; Eirenschmalz, L.; Joeckel, P.; Mertens, M.; Fisher, R.; Bauguitte, S.; Young, S.; Andrés Hernández, M. D.

    2017-12-01

    Urban environments represent large and diffuse area sources of CH4 including emissions from pipeline leaks, industrial/sewage treatment plants, and landfills. However, there is little knowledge about the exact magnitude of these emissions and their contribution to total anthropogenic CH4. Especially in the context of an urbanizing world, a better understanding of the methane footprint of urban areas is crucial, both with respect to mitigation and projection of climate impacts. Aircraft-borne in-situ measurements are particularly useful to both quantify emissions from such area sources, as well as to study their impact on the regional distribution. However, airborne CH4 observations downstream of European cities are especially sparse.Here we report from aircraft-borne CH4 in-situ measurements as conducted during the HALO aircraft campaign EMeRGe (Effect of Megacities on the Transport and Transformation of Pollutants on the Regional to Global Scales) in July 2017, which was led by the University of Bremen, Germany. During seven research flights, emissions from a variety of European (Mega)-cities were probed at different altitudes from 3km down to 500m, including measurements in the outflows of London, Rome, Po Valley, Ruhr and Benelux. We will present and compare the CH4 distribution measured downstream of the various studied urban hot-spots. With the help of other trace gas measurements (including e.g. CO2, CO, O3, SO2), observed methane enhancements will be attributed to the different potential source types. Finally, by the combination of in-situ measurements and regional model simulations using the EMAC-MECO(n) model, the contribution of emissions from urban centers to the regional methane budget over Europe will be discussed.

  13. Single-Center Study Investigating Foreign Language Acquisition at School in Children, Adolescents, and Young Adults With Uni- or Bilateral Cochlear Implants in the Swiss German Population.

    Science.gov (United States)

    Beeres-Scheenstra, Renske; Ohnsorg, Claudia; Candreia, Claudia; Heinzmann, Sybille; Castellanos, Susana; De Min, Nicola; Linder, Thomas E

    2017-07-01

    To evaluate foreign language acquisition at school in cochlear implant patients. Cohort study. CI center. Forty three cochlear implants (CI) patients (10-18 yr) were evaluated. CI nonusers and patients with CI-explantation, incomplete datasets, mental retardation, or concomitant medical disorders were excluded. Additional data (type of schooling, foreign language learning, and bilingualism) were obtained with questionnaires. German-speaking children with foreign tuition language (English and/or French) at school were enrolled for further testing. General patient data, auditory data, and foreign language data from both questionnaires and tests were collected and analyzed. Thirty seven out of 43 questionnaires (86%) were completed. Sixteen (43%) were in mainstream education. Twenty-seven CI users (73%) have foreign language learning at school. Fifteen of these were in mainstream education (55%), others in special schooling. From 10 CI users without foreign language learning, one CI user was in mainstream education (10%) and nine patients (90%) were in special schooling. Eleven German-speaking CI users were further tested in English and six additionally in French. For reading skills, the school objectives for English were reached in 7 of 11 pupils (64%) and for French in 3 of 6 pupils (50%). For listening skills, 3 of 11 pupils (27%) reached the school norm in English and none in French. Almost 75% of our CI users learn foreign language(s) at school. A small majority of the tested CI users reached the current school norm for in English and French in reading skills, whereas for hearing skills most of them were not able to reach the norm.

  14. Distribution and Modeled Transport of Plastic Pollution in the Great Lakes, the World's Largest Freshwater Resource

    Directory of Open Access Journals (Sweden)

    Rachel N. Cable

    2017-07-01

    Full Text Available Most plastic pollution originates on land. As such, freshwater bodies serve as conduits for the transport of plastic litter to the ocean. Understanding the concentrations and fluxes of plastic litter in freshwater ecosystems is critical to our understanding of the global plastic litter budget and underpins the success of future management strategies. We conducted a replicated field survey of surface plastic concentrations in four lakes in the North American Great Lakes system, the largest contiguous freshwater system on the planet. We then modeled plastic transport to resolve spatial and temporal variability of plastic distribution in one of the Great Lakes, Lake Erie. Triplicate surface samples were collected at 38 stations in mid-summer of 2014. Plastic particles >106 μm in size were quantified. Concentrations were highest near populated urban areas and their water infrastructure. In the highest concentration trawl, nearly 2 million fragments km−2 were found in the Detroit River—dwarfing previous reports of Great Lakes plastic abundances by over 4-fold. Yet, the accuracy of single trawl counts was challenged: within-station plastic abundances varied 0- to 3-fold between replicate trawls. In the smallest size class (106–1,000 μm, false positive rates of 12–24% were determined analytically for plastic vs. non-plastic, while false negative rates averaged ~18%. Though predicted to form in summer by the existing Lake Erie circulation model, our transport model did not predict a permanent surface “Lake Erie Garbage Patch” in its central basin—a trend supported by field survey data. Rather, general eastward transport with recirculation in the major basins was predicted. Further, modeled plastic residence times were drastically influenced by plastic buoyancy. Neutrally buoyant plastics—those with the same density as the ambient water—were flushed several times slower than plastics floating at the water's surface and exceeded the

  15. Rib fracture fixation in the 65 years and older population: A paradigm shift in management strategy at a Level I trauma center.

    Science.gov (United States)

    Fitzgerald, Michael T; Ashley, Dennis W; Abukhdeir, Hesham; Christie, D Benjamin

    2017-03-01

    Rib fractures after chest wall trauma are a common injury; however, they carry a significant morbidity and mortality risk. The impact of rib fractures in the 65-year and older patient population has been well documented as have the mortality and pneumonia rates. We hypothesize that patients 65 years and older receiving rib plating (RP) have decreased mortality, complication rates, and an accelerated return to normal functional states when compared with controls. With institutional review board approval, a retrospective review analyzed patients 65 years and older with rib fractures admitted from 2009 to 2015 receiving RP (RP group) (n = 23) compared to nonoperative, injury-matched controls admitted from 2003 to 2008 (NO group) (n = 50). Patients were followed prospectively with regard to lifestyle and functional satisfaction. Independent variables analyzed included Injury Severity Score (ISS), number of rib fractures, mortalities, hospital days, intensive care unit days, pneumonia development, respiratory complications, readmission rates, need for and length of rehabilitation stay time. Comparisons were by χ tests/Fisher's exact tests, Student's t tests and Wilcoxon rank sum tests. From 2003 to 2008, 50 NO patients were admitted with ages ranging 65 to 97 years, average ISS of 18.47 (14.28-22.66) versus ages ranging from 63 to 89 years, average ISS of 20.71 (15.7-25.73) for the RP group (n = 23). Average hospital days were 16.76 (10.35-23.18) and 18.36 (13.61-23.11) in the NO and RP groups, respectively. Average intensive care unit days were 11.65 (6.45-16.85) and 8.29 (5.31-11.26) days in the NO and RP groups, respectively. Four respiratory readmissions, two deaths, seven pneumonias, seven pleural-effusions, and 19 recurrent pneumothoraces were encountered in the NO group versus 0 in the RP group (p < 0.001). An equal percentage of patients in both groups entered rehabilitation facilities with average stay time of 18.5 and 28.53 days for the RP and NO groups

  16. Is exposure to Agent Orange a risk factor for hepatocellular cancer?-A single-center retrospective study in the U.S. veteran population.

    Science.gov (United States)

    Krishnamurthy, Padmini; Hazratjee, Nyla; Opris, Dan; Agrawal, Sangeeta; Markert, Ronald

    2016-06-01

    factors for HCC development in this U.S. veteran population. There was no significant association between exposure to Agent Orange and HCC, although larger studies are needed in the U.S. military veteran population to evaluate further this toxic herbicide from the Vietnam War era.

  17. Evaluation inquiry of the provision of iodine tablets to the populations living in the vicinity of the nuclear center of electric production at Bugey, september 1998

    International Nuclear Information System (INIS)

    Helynck, B.; Rey, S.; Malfait, Ph.; Dubois, M.C.

    2002-01-01

    50 % of households in the area of the particular plan of intervention (P.P.I.) of Bugey N.P.P. had removed the iodine tablets. This cover is insufficient, when the Ministry circular considered an availability of tablets in every household. The inquiry highlighted a relationship with between the removal of tablets and knowledge about iodine, but the results suggest that this information campaign was not enough efficient. This situation is worrying, because of the expiry date of the tablets, new campaigns are to be done regularly. In order to improve the results of future campaigns, it is important to take into account feedbacks of the first distribution. The information sources must be diversified. Health professionals should be involved. The Institutions in charge of health in children (Service of maternal and infants protection and service for the promotion of health for students) should also be involved. Simplification and clarity of messages must be improved, especially towards priority populations such young parents, pregnant women. (N.C.)

  18. Association of coffee intake with total and cause-specific mortality in a Japanese population: the Japan Public Health Center-based Prospective Study.

    Science.gov (United States)

    Saito, Eiko; Inoue, Manami; Sawada, Norie; Shimazu, Taichi; Yamaji, Taiki; Iwasaki, Motoki; Sasazuki, Shizuka; Noda, Mitsuhiko; Iso, Hiroyasu; Tsugane, Shoichiro

    2015-05-01

    Despite the rising consumption of coffee worldwide, few prospective cohort studies assessed the association of coffee intake with mortality including total and major causes of death. We aimed to investigate the association between habitual coffee drinking and mortality from all causes, cancer, heart disease, cerebrovascular disease, respiratory disease, injuries, and other causes of death in a large-scale, population-based cohort study in Japan. We studied 90,914 Japanese persons aged between 40 and 69 y without a history of cancer, cerebrovascular disease, or ischemic heart disease at the time of the baseline study. Subjects were followed up for an average of 18.7 y, during which 12,874 total deaths were reported. The association between coffee intake and risk of total and cause-specific mortality was assessed by using a Cox proportional hazards regression model with adjustment for potential confounders. We showed an inverse association between coffee intake and total mortality in both men and women. HRs (95% CIs) for total death in subjects who consumed coffee compared with those who never drank coffee were 0.91 (0.86-0.95) for 5 cups/d (P-trend Coffee was inversely associated with mortality from heart disease, cerebrovascular disease, and respiratory disease. With this prospective study, we suggest that the habitual intake of coffee is associated with lower risk of total mortality and 3 leading causes of death in Japan. © 2015 American Society for Nutrition.

  19. Discovery of the Largest Orbweaving Spider Species: The Evolution of Gigantism in Nephila

    OpenAIRE

    Kuntner, Matja?; Coddington, Jonathan A.

    2009-01-01

    Background More than 41,000 spider species are known with about 400?500 added each year, but for some well-known groups, such as the giant golden orbweavers, Nephila, the last valid described species dates from the 19th century. Nephila are renowned for being the largest web-spinning spiders, making the largest orb webs, and are model organisms for the study of extreme sexual size dimorphism (SSD) and sexual biology. Here, we report on the discovery of a new, giant Nephila species from Africa...

  20. Secular trends of blood isolates in patients from a rural area population hospitalized in a tertiary center in a small city in Greece

    Directory of Open Access Journals (Sweden)

    Holevas Pierros V

    2006-05-01

    Full Text Available Abstract Background Most of the studies evaluating the secular trends of blood isolates come from tertiary hospitals in urban areas. We sought to study the trends of the antimicrobial resistance of blood isolates in patients from a rural population hospitalized in a tertiary hospital in a small city in Greece. Methods We retrospectively collected and analysed data for the first positive blood culture obtained for each admission for each patient hospitalized in General Hospital of Tripolis, Tripolis, Peloponnesus, Greece during a 5 year period (16/05/2000 – 15/05/2005. Results Sixty-seven thousand and seventy patients were hospitalized during the study period from whom 3,206 blood cultures were obtained. A higher increase of the number of obtained blood cultures than the number of admissions was noted during the study period (p Escherichia coli (29%, and Staphylococcus aureus (18.2% were the most commonly isolated pathogens. Among the Staphylococcus aureus isolates, the proportion of methicillin-resistant Staphylococcus aureus (MRSA was 17.2% (5/29. The proportion of Escherichia coli resistant to trimethoprim and sulfamethoxazole, ampicillin and cefuroxime was 29.6% (32/108, 25.0% (27/108, and 8.3% (9/108 respectively. Imipenem-resistance was noted in 3.4% (1/29 of Pseudomonas aeruginosa isolates. There were only 6 (1.6% Acinetobacter baummanii blood isolates during the study period. Conclusion The antimicrobial resistance of isolates from patients receiving care at the studied tertiary hospital in a small city in Greece is considerably less compared to that noted in tertiary hospitals in larger cities of the country.

  1. A risk prediction score model for predicting occurrence of post-PCI vasovagal reflex syndrome: a single center study in Chinese population.

    Science.gov (United States)

    Li, Hai-Yan; Guo, Yu-Tao; Tian, Cui; Song, Chao-Qun; Mu, Yang; Li, Yang; Chen, Yun-Dai

    2017-08-01

    The vasovagal reflex syndrome (VVRS) is common in the patients undergoing percutaneous coronary intervention (PCI). However, prediction and prevention of the risk for the VVRS have not been completely fulfilled. This study was conducted to develop a Risk Prediction Score Model to identify the determinants of VVRS in a large Chinese population cohort receiving PCI. From the hospital electronic medical database, we identified 3550 patients who received PCI (78.0% males, mean age 60 years) in Chinese PLA General Hospital from January 1, 2000 to August 30, 2016. The multivariate analysis and receiver operating characteristic (ROC) analysis were performed. The adverse events of VVRS in the patients were significantly increased after PCI procedure than before the operation (all P PCI was 4.5% (4.1%-5.6%). Compared to the patients suffering no VVRS, incidence of VVRS involved the following factors, namely female gender, primary PCI, hypertension, over two stents implantation in the left anterior descending (LAD), and the femoral puncture site. The multivariate analysis suggested that they were independent risk factors for predicting the incidence of VVRS (all P PCI (c-statistic 0.76, 95% CI: 0.72-0.79, P PCI whose diastolic blood pressure dropped by more than 30 mmHg and heart rate reduced by 10 times per minute (AUC: 0.84, 95% CI: 0.81-0.87, P PCI. In which, the following factors may be involved, the femoral puncture site, female gender, hypertension, primary PCI, and over 2 stents implanted in LAD.

  2. Population catastrophe.

    Science.gov (United States)

    Ankomah, B

    1990-07-01

    UNFPA estimates predict that Africa's population will be 1.5 billion by 2025. In the next 10 years the growth rate will be 3%, the highest for any region in human history. Nigeria is expected to have 301 million people in 35 years, making it the 3rd largest country behind India and China. Currently the economies of African countries can not provide enough jobs or food for the current population. What is going to happen in 35 years when the population will almost double? In 1950 Africa only made up 9% of the world population, but by 2025 it will be 18.4% of a global population of 8.4 billion. Currently half of Africa's population is under 15. This means that there is still time to affect change. There is time to convince this generation not to behave like their parents. A 2 child limit per family is an absolute limit if any progress is to be made that will actually have an effect. Many have suggested that the young people should go back to the land instead of living in poverty in the city. However, currently the land distribution is 0.4 hectares/rural person. This figure is going to drop to 0.29/rural person. Migration is simply not the solution. Many rural farmers want to have enough children to ensure that their land is inherited and stays in the family. The same goal can be achieved, with less children. According to the UNFPA 77% of married women who do not want to have more children do not use contraceptives. Only 14% of African women use contraceptives, so that by age 20 50% of African women have had 1 birth. The only way to seriously cut down the birth rate is to get the men of Africa involved in contraceptive use.

  3. Complete Genome Sequence of the Largest Known Flavi-Like Virus, Diaphorina citri flavi-like virus, a Novel Virus of the Asian Citrus Psyllid, Diaphorina citri.

    Science.gov (United States)

    Matsumura, Emilyn E; Nerva, Luca; Nigg, Jared C; Falk, Bryce W; Nouri, Shahideh

    2016-09-08

    A novel flavi-like virus tentatively named Diaphorina citri flavi-like virus (DcFLV) was identified in field populations of Diaphorina citri through small RNA and transcriptome sequencing followed by reverse transcription (RT)-PCR. We report here the complete nucleotide sequence and genome organization of DcFLV, the largest flavi-like virus identified to date. Copyright © 2016 Matsumura et al.

  4. Usage Center

    DEFF Research Database (Denmark)

    Kleinaltenkamp, Michael; Plewa, Carolin; Gudergan, Siegfried

    2017-01-01

    Purpose: The purpose of this paper is to advance extant theorizing around resourceintegration by conceptualizing and delineating the notion of a usage center. Ausage center consists of a combination of interdependent actors that draw onresources across their individual usage processes to create v...

  5. Mass balance of Greenland's three largest outlet glaciers - 2000–2010

    NARCIS (Netherlands)

    Howat, I.M.; Ahn, Y.; Joughin, I.; van den Broeke, M.R.; Lenaerts, J.T.M.; Smith, B.

    2011-01-01

    Acceleration of Greenland's three largest outlet glaciers, Helheim, Kangerdlugssuaq and Jakobshavn Isbræ, accounted for a substantial portion of the ice sheet's mass loss over the past decade. Rapid changes in their discharge, however, make their cumulative mass-change uncertain. We derive monthly

  6. Key U.S.-built part fails during testing for world's largest particle collider

    CERN Multimedia

    2007-01-01

    "Scientists are scrambling to redesign a key U.S.-built part that broke "with a loud bang and a cloud of dust" during a high-pressure test for the world's largest particle physics collider that is supposed to start up in November, officials sais Tuesday." (1,5 page)

  7. CERN, World's largest particle physics lab, selects Progress SonicMQ

    CERN Document Server

    2007-01-01

    "Progress Software Corporation (NADAQ: PRGS), a global supplier of application insfrastructure software used to develop, deploy, integrate and manage business applications, today announced that CERN the world's largest physis laboratory and particle accelerator, has chosen Progress® SonicMQ® for mission-critical message delivery." (1 page)

  8. Phase space reconstruction and estimation of the largest Lyapunov exponent for gait kinematic data

    Energy Technology Data Exchange (ETDEWEB)

    Josiński, Henryk [Silesian University of Technology, Akademicka 16, 44-100 Gliwice (Poland); Świtoński, Adam [Polish-Japanese Institute of Information Technology, Aleja Legionów 2, 41-902 Bytom (Poland); Silesian University of Technology, Akademicka 16, 44-100 Gliwice (Poland); Michalczuk, Agnieszka; Wojciechowski, Konrad [Polish-Japanese Institute of Information Technology, Aleja Legionów 2, 41-902 Bytom (Poland)

    2015-03-10

    The authors describe an example of application of nonlinear time series analysis directed at identifying the presence of deterministic chaos in human motion data by means of the largest Lyapunov exponent. The method was previously verified on the basis of a time series constructed from the numerical solutions of both the Lorenz and the Rössler nonlinear dynamical systems.

  9. Discovery of the largest orbweaving spider species: the evolution of gigantism in Nephila.

    Science.gov (United States)

    Kuntner, Matjaz; Coddington, Jonathan A

    2009-10-21

    More than 41,000 spider species are known with about 400-500 added each year, but for some well-known groups, such as the giant golden orbweavers, Nephila, the last valid described species dates from the 19(th) century. Nephila are renowned for being the largest web-spinning spiders, making the largest orb webs, and are model organisms for the study of extreme sexual size dimorphism (SSD) and sexual biology. Here, we report on the discovery of a new, giant Nephila species from Africa and Madagascar, and review size evolution and SSD in Nephilidae. We formally describe N. komaci sp. nov., the largest web spinning species known, and place the species in phylogenetic context to reconstruct the evolution of mean size (via squared change parsimony). We then test female and male mean size correlation using phylogenetically independent contrasts, and simulate nephilid body size evolution using Monte Carlo statistics. Nephila females increased in size almost monotonically to establish a mostly African clade of true giants. In contrast, Nephila male size is effectively decoupled and hovers around values roughly one fifth of female size. Although N. komaci females are the largest Nephila yet discovered, the males are also large and thus their SSD is not exceptional.

  10. Predicting Traffic Flow in Local Area Networks by the Largest Lyapunov Exponent

    Directory of Open Access Journals (Sweden)

    Yan Liu

    2016-01-01

    Full Text Available The dynamics of network traffic are complex and nonlinear, and chaotic behaviors and their prediction, which play an important role in local area networks (LANs, are studied in detail, using the largest Lyapunov exponent. With the introduction of phase space reconstruction based on the time sequence, the high-dimensional traffic is projected onto the low dimension reconstructed phase space, and a reduced dynamic system is obtained from the dynamic system viewpoint. Then, a numerical method for computing the largest Lyapunov exponent of the low-dimensional dynamic system is presented. Further, the longest predictable time, which is related to chaotic behaviors in the system, is studied using the largest Lyapunov exponent, and the Wolf method is used to predict the evolution of the traffic in a local area network by both Dot and Interval predictions, and a reliable result is obtained by the presented method. As the conclusion, the results show that the largest Lyapunov exponent can be used to describe the sensitivity of the trajectory in the reconstructed phase space to the initial values. Moreover, Dot Prediction can effectively predict the flow burst. The numerical simulation also shows that the presented method is feasible and efficient for predicting the complex dynamic behaviors in LAN traffic, especially for congestion and attack in networks, which are the main two complex phenomena behaving as chaos in networks.

  11. Discovery of the largest orbweaving spider species: the evolution of gigantism in Nephila.

    Directory of Open Access Journals (Sweden)

    Matjaz Kuntner

    2009-10-01

    Full Text Available More than 41,000 spider species are known with about 400-500 added each year, but for some well-known groups, such as the giant golden orbweavers, Nephila, the last valid described species dates from the 19(th century. Nephila are renowned for being the largest web-spinning spiders, making the largest orb webs, and are model organisms for the study of extreme sexual size dimorphism (SSD and sexual biology. Here, we report on the discovery of a new, giant Nephila species from Africa and Madagascar, and review size evolution and SSD in Nephilidae.We formally describe N. komaci sp. nov., the largest web spinning species known, and place the species in phylogenetic context to reconstruct the evolution of mean size (via squared change parsimony. We then test female and male mean size correlation using phylogenetically independent contrasts, and simulate nephilid body size evolution using Monte Carlo statistics.Nephila females increased in size almost monotonically to establish a mostly African clade of true giants. In contrast, Nephila male size is effectively decoupled and hovers around values roughly one fifth of female size. Although N. komaci females are the largest Nephila yet discovered, the males are also large and thus their SSD is not exceptional.

  12. World's third-largest producer of nuclear power. Japan in need of energy

    International Nuclear Information System (INIS)

    Anon.

    2008-01-01

    Japan is the third largest oil consumer in the world behind the United States and China, and the second largest net importer of oil. Japan boasts one of the largest economies in the world. The country continues to experience a moderate economic recovery that began in 2003, following a decade of economic stagnation. Japan's real gross domestic product (GDP) grew by 2.5% in 2005 and 2.3% in 2004. The modest upturn over the last few years reflects higher business confidence in Japan, a surge in export demand led by exports to China, and robust consumer spending. Unemployment in Japan fell to 4.4% in 2005, down from an early 2003 peak of 5.5%. Japan has virtually no domestic oil or natural gas reserves, and in 2005 was the second largest net importer of crude oil in the world. Despite the country's dearth of hydrocarbon resources, Japanese companies have actively pursued upstream oil and natural gas projects overseas. Japan remains one of the major exporters of energy-sector capital equipment, and Japanese companies provide engineering, construction, and project management services for energy projects. (orig.)

  13. Distribution of the Largest Eigenvalues of the Levi-Smirnov Ensemble

    International Nuclear Information System (INIS)

    Wieczorek, W.

    2004-01-01

    We calculate the distribution of the k-th largest eigenvalue in the random matrix Levi - Smirnov Ensemble (LSE), using the spectral dualism between LSE and chiral Gaussian Unitary Ensemble (GUE). Then we reconstruct universal spectral oscillations and we investigate an asymptotic behavior of the spectral distribution. (author)

  14. Lessons from the Largest Epidemic of Avian Influenza Viruses in Taiwan, 2015.

    Science.gov (United States)

    Chang, Ching-Fen; King, Chwan-Chuen; Wan, Cho-Hua; Chang, Yun-Cheng; Chan, Ta-Chien; David Lee, Chang-Chun; Chou, Po-Hao Borris; Li, Zheng-Rong Tiger; Li, Yao-Tsun; Tseng, Tzu-Jung; Lee, Pei-Fen; Chang, Chuan-Hsiung

    2016-05-01

    The largest epidemic of avian influenza (AI) in history attacked poultry and wild birds throughout Taiwan starting January 6, 2015. This study analyzed surveillance results, epidemiologic characteristics, and viral sequences by using government-released information, with the intention to provide recommendations to minimize future pandemic influenza. The H5 clade 2.3.4.4 highly pathogenic AI viruses (HPAIVs) had not been detected in Taiwan before 2015. During this epidemic, four types of etiologic agents were identified: the three novel subtypes H5N2, H5N8, and H5N3 clade 2.3.4.4 HPAIVs and one endemic chicken H5N2 subtype (Mexican-like lineage) of low pathogenic AI viruses. Cocirculation of mixed subtypes also occurred, with H5N2 clade 2.3.4.4 HPAIVs accompanied by the H5N8 and H5N3 subtypes or old H5N2 viruses in the same farm. More than 90% of domestic geese died from this AI epidemic; geese were affected the most at the early outbreaks. The epidemic peaked in mid-January for all three novel H5 subtypes. Spatial epidemiology found that most affected areas were located in southwestern coastal areas. In terrestrial poultry (mostly chickens), different geographic distributions of AI virus subtypes were detected, with hot spots of H5N2 clade 2.3.4.4 vs. past-endemic old H5N2 viruses in Changhwa (P = 0.03) and Yunlin (P = 0.007) counties, respectively, of central Taiwan. Phylogenetic and sequence analyses of all the early 10 Taiwan H5 clade 2.3.4.4 isolates covering the three subtypes showed that they were very different from the HA of the past local H5 viruses from domestic ducks (75%-80%) and chickens (70%-75%). However, they had the highest sequence identity percentages (99.53%-100%), with the HA of A/crane/Kagoshima/KU13/2014(H5N8) isolated on December 7, 2014, in Japan being higher than those of recent American and Korean H5 HPAIVs [A/Northern pintail/Washington/40964/2014 (H5N2) and A/gyrfalcon/Washington/41088-6/2014 (H5N8): 99.02%-99.54% and A/Baikal teal

  15. Differential genome-wide gene expression profiling of bovine largest and second-largest follicles: identification of genes associated with growth of dominant follicles

    Directory of Open Access Journals (Sweden)

    Takahashi Toru

    2010-02-01

    Full Text Available Abstract Background Bovine follicular development is regulated by numerous molecular mechanisms and biological pathways. In this study, we tried to identify differentially expressed genes between largest (F1 and second-largest follicles (F2, and classify them by global gene expression profiling using a combination of microarray and quantitative real-time PCR (QPCR analysis. The follicular status of F1 and F2 were further evaluated in terms of healthy and atretic conditions by investigating mRNA localization of identified genes. Methods Global gene expression profiles of F1 (10.7 +/- 0.7 mm and F2 (7.8 +/- 0.2 mm were analyzed by hierarchical cluster analysis and expression profiles of 16 representative genes were confirmed by QPCR analysis. In addition, localization of six identified transcripts was investigated in healthy and atretic follicles using in situ hybridization. The healthy or atretic condition of examined follicles was classified by progesterone and estradiol concentrations in follicular fluid. Results Hierarchical cluster analysis of microarray data classified the follicles into two clusters. Cluster A was composed of only F2 and was characterized by high expression of 31 genes including IGFBP5, whereas cluster B contained only F1 and predominantly expressed 45 genes including CYP19 and FSHR. QPCR analysis confirmed AMH, CYP19, FSHR, GPX3, PlGF, PLA2G1B, SCD and TRB2 were greater in F1 than F2, while CCL2, GADD45A, IGFBP5, PLAUR, SELP, SPP1, TIMP1 and TSP2 were greater in F2 than in F1. In situ hybridization showed that AMH and CYP19 were detected in granulosa cells (GC of healthy as well as atretic follicles. PlGF was localized in GC and in the theca layer (TL of healthy follicles. IGFBP5 was detected in both GC and TL of atretic follicles. GADD45A and TSP2 were localized in both GC and TL of atretic follicles, whereas healthy follicles expressed them only in GC. Conclusion We demonstrated that global gene expression profiling of F

  16. Loss of largest and oldest individuals of the Montpellier snake correlates with recent warming in the southeastern Iberian Peninsula.

    Science.gov (United States)

    López-Calderón, Cosme; Feriche, Mónica; Alaminos, Esmeralda; Pleguezuelos, Juan M

    2017-12-01

    The effects of climate change on organisms are now being extensively studied in many different taxa. However, the variation in body size, usually shrinkage in response to increasing temperature, has received little attention regarding to reptiles. During past periods of global warming, many organisms shrank in size, and current evidence and experiments manipulating temperature have shown a biomass decrease in some organisms with increasing temperatures. Here we test whether the body size of the Montpellier snake Malpolon monspessulanus from the southeastern Iberian Peninsula is changing and correlated with the increasing temperature in this region during a 39-year period (1976-2014). We measured the snout-vent length (SVL) of vouchers in scientific collections to check for trends in adult body size at the population level in relation with temperature, while controlling for the age of the individuals (estimated by skeletochronology, n  =141). Given the great ontogenetic variation in body size of the study species, we categorized age in 3 classes: "young adults" (under 5 years old), "intermediate adults" (from 5 to 7 years old), and "old adults" (from 8 to 14 years old). By means of linear mixed models, we found a negative relationship between SVL of "old adults" and average annual temperature in the region during the lifetime of each individual. Our results indicate that largest and oldest individuals of the Montpellier Snake, that is, males because of strong sexual size dimorphism in this species, disappeared from the study population, and suggest that it occurred in response to rising environmental temperature.

  17. Analysis of Multiple Structural Changes in Financial Contagion Based on the Largest Lyapunov Exponents

    Directory of Open Access Journals (Sweden)

    Rui Wang

    2014-01-01

    Full Text Available A modified multiple structural changes model is built to test structural breaks of the financial system based on calculating the largest Lyapunov exponents of the financial time series. Afterwards, the Lorenz system is used as a simulation example to inspect the new model. As the Lorenz system has strong nonlinearity, the verification results show that the new model has good capability in both finding the breakpoint and revealing the changes in nonlinear characteristics of the time series. The empirical study based on the model used daily data from the S&P 500 stock index during the global financial crisis from 2005 to 2012. The results provide four breakpoints of the period, which divide the contagion into four stages: stationary, local outbreak, global outbreak, and recovery period. An additional significant result is the obvious chaos characteristic difference in the largest Lyapunov exponents and the standard deviation at various stages, particularly at the local outbreak stage.

  18. Constraining the magnitude of the largest event in a foreshock-main shock-aftershock sequence

    Science.gov (United States)

    Shcherbakov, Robert; Zhuang, Jiancang; Ogata, Yosihiko

    2018-01-01

    Extreme value statistics and Bayesian methods are used to constrain the magnitudes of the largest expected earthquakes in a sequence governed by the parametric time-dependent occurrence rate and frequency-magnitude statistics. The Bayesian predictive distribution for the magnitude of the largest event in a sequence is derived. Two types of sequences are considered, that is, the classical aftershock sequences generated by large main shocks and the aftershocks generated by large foreshocks preceding a main shock. For the former sequences, the early aftershocks during a training time interval are used to constrain the magnitude of the future extreme event during the forecasting time interval. For the latter sequences, the earthquakes preceding the main shock are used to constrain the magnitudes of the subsequent extreme events including the main shock. The analysis is applied retrospectively to past prominent earthquake sequences.

  19. Draft sequencing and assembly of the genome of the world's largest fish, the whale shark: Rhincodon typus Smith 1828.

    Science.gov (United States)

    Read, Timothy D; Petit, Robert A; Joseph, Sandeep J; Alam, Md Tauqeer; Weil, M Ryan; Ahmad, Maida; Bhimani, Ravila; Vuong, Jocelyn S; Haase, Chad P; Webb, D Harry; Tan, Milton; Dove, Alistair D M

    2017-07-14

    The whale shark (Rhincodon typus) has by far the largest body size of any elasmobranch (shark or ray) species. Therefore, it is also the largest extant species of the paraphyletic assemblage commonly referred to as fishes. As both a phenotypic extreme and a member of the group Chondrichthyes - the sister group to the remaining gnathostomes, which includes all tetrapods and therefore also humans - its genome is of substantial comparative interest. Whale sharks are also listed as an endangered species on the International Union for Conservation of Nature's Red List of threatened species and are of growing popularity as both a target of ecotourism and as a charismatic conservation ambassador for the pelagic ecosystem. A genome map for this species would aid in defining effective conservation units and understanding global population structure. We characterised the nuclear genome of the whale shark using next generation sequencing (454, Illumina) and de novo assembly and annotation methods, based on material collected from the Georgia Aquarium. The data set consisted of 878,654,233 reads, which yielded a draft assembly of 1,213,200 contigs and 997,976 scaffolds. The estimated genome size was 3.44Gb. As expected, the proteome of the whale shark was most closely related to the only other complete genome of a cartilaginous fish, the holocephalan elephant shark. The whale shark contained a novel Toll-like-receptor (TLR) protein with sequence similarity to both the TLR4 and TLR13 proteins of mammals and TLR21 of teleosts. The data are publicly available on GenBank, FigShare, and from the NCBI Short Read Archive under accession number SRP044374. This represents the first shotgun elasmobranch genome and will aid studies of molecular systematics, biogeography, genetic differentiation, and conservation genetics in this and other shark species, as well as providing comparative data for studies of evolutionary biology and immunology across the jawed vertebrate lineages.

  20. Investigation of Science Faculty with Education Specialties within the Largest University System in the United States

    OpenAIRE

    Bush, Seth D; Pelaez, Nancy; Rudd, James A, II; Stevens, Michael T; Tanner, Kimberly D; Williams, Kathy, PhD

    2011-01-01

    Efforts to improve science education include university science departments hiring Science Faculty with Education Specialties (SFES), scientists who take on specialized roles in science education within their discipline. Although these positions have existed for decades and may be growing more common, few reports have investigated the SFES approach to improving science education. We present comprehensive data on the SFES in the California State University (CSU) system, the largest university ...

  1. Opportunities for biodiversity gains under the world’s largest reforestation programme

    OpenAIRE

    Hua, Fangyuan; Wang, Xiaoyang; Zheng, Xinlei; Fisher, Brendan; Wang, Lin; Zhu, Jianguo; Tang, Ya; Yu, Douglas W.; Wilcove, David S.

    2016-01-01

    Reforestation is a critical means of addressing the environmental and social problems of deforestation. China’s Grain-for-Green Program (GFGP) is the world’s largest reforestation scheme. Here we provide the first nationwide assessment of the tree composition of GFGP forests and the first combined ecological and economic study aimed at understanding GFGP’s biodiversity implications. Across China, GFGP forests are overwhelmingly monocultures or compositionally simple mixed forests. Focusing on...

  2. Trend of CO2 emissions of the 30 largest power plants in Germany

    International Nuclear Information System (INIS)

    Hermann, Hauke

    2014-01-01

    The brochure on the trend of CO 2 emissions of the 30 largest power plants in Germany includes tables of the emissions of these power plants. The CO 2 emissions of these power plants in 2013 (25% of the total German greenhouse gas emissions) have increased by 5% compared to 2012. The total CO 2 emission sin Germany increased by 1.5%. The differences between brown coal and black coal fired power plants are discussed.

  3. Natural radionuclides in soil profiles surrounding the largest coal-fired power plant in Serbia

    OpenAIRE

    Tanić Milan N.; Janković-Mandić Ljiljana J.; Gajić Boško A.; Daković Marko Z.; Dragović Snežana D.; Bačić Goran G.

    2016-01-01

    This study evaluates the influence of the largest Serbian coal-fired power plant on radionuclide concentrations in soil profiles up to 50 cm in depth. Thirty soil profiles were sampled from the plant surroundings (up to 10 km distance) and analyzed using standard methods for soil physicochemical properties and gamma ray spectrometry for specific activities of natural radionuclides (40K, 226Ra and 232Th). Spatial and vertical distribution of radionuclides wa...

  4. THE MASS OF (4) VESTA DERIVED FROM ITS LARGEST GRAVITATIONAL EFFECTS

    International Nuclear Information System (INIS)

    Kuzmanoski, Mike; Novakovic, Bojan; Apostolovska, Gordana

    2010-01-01

    In this paper, we present a recalculated value of the mass of (4) Vesta, derived from its largest gravitational perturbations on selected asteroids during their mutual close encounters. This was done by using a new method for mass determination, which is based on the linking of pre-encounter observations to the orbit determined from post-encounter ones. The estimated weighted mean of the mass of (4) Vesta is (1.300 ± 0.001) x 10 -10 M sun .

  5. THE CHALLENGE OF THE LARGEST STRUCTURES IN THE UNIVERSE TO COSMOLOGY

    International Nuclear Information System (INIS)

    Park, Changbom; Choi, Yun-Young; Kim, Sungsoo S.; Kim, Kap-Sung; Kim, Juhan; Gott III, J. Richard

    2012-01-01

    Large galaxy redshift surveys have long been used to constrain cosmological models and structure formation scenarios. In particular, the largest structures discovered observationally are thought to carry critical information on the amplitude of large-scale density fluctuations or homogeneity of the universe, and have often challenged the standard cosmological framework. The Sloan Great Wall (SGW) recently found in the Sloan Digital Sky Survey (SDSS) region casts doubt on the concordance cosmological model with a cosmological constant (i.e., the flat ΛCDM model). Here we show that the existence of the SGW is perfectly consistent with the ΛCDM model, a result that only our very large cosmological N-body simulation (the Horizon Run 2, HR2) could supply. In addition, we report on the discovery of a void complex in the SDSS much larger than the SGW, and show that such size of the largest void is also predicted in the ΛCDM paradigm. Our results demonstrate that an initially homogeneous isotropic universe with primordial Gaussian random phase density fluctuations growing in accordance with the general relativity can explain the richness and size of the observed large-scale structures in the SDSS. Using the HR2 simulation we predict that a future galaxy redshift survey about four times deeper or with 3 mag fainter limit than the SDSS should reveal a largest structure of bright galaxies about twice as big as the SGW.

  6. On the statistics of the largest geomagnetic storms per solar cycle

    International Nuclear Information System (INIS)

    Siscoe, G.L.

    1976-01-01

    The theory of extreme value statistics is applied to the first, second, and third largest geomagnetic storms in nine solar cycles measured by the average half-daily aa indices compiled by Mayaud. Analytic expressions giving the probability of the extremes per solar cycle as a contour function of storm magnitude are obtained by least squares fitting of the observations to the appropriate theoretical extreme value probability functions. The results are used to obtain the statistical characteristics (mode, median, mean, and standard deviation) for the extreme values. The results are applied to find the expected range of extreme values in a set as a function of the number of solar cycles in the set. We find that the expected range of the largest storm is quite narrow and is larger for the second and third largest storms. The observed range of the extreme half-daily aa index for the nine solar cycles is 354--546 γ. In a set of 100 cycles the range is expanded esentially to 311--680γ, an increase of only 39% in the range. The result supports the argument for a change in solar cycle statistics in the latter part of the Seventeenth Century (the Maunder minimum)

  7. Hospital Prices Increase in California, Especially Among Hospitals in the Largest Multi-hospital Systems

    Directory of Open Access Journals (Sweden)

    Glenn A. Melnick PhD

    2016-06-01

    Full Text Available A surge in hospital consolidation is fueling formation of ever larger multi-hospital systems throughout the United States. This article examines hospital prices in California over time with a focus on hospitals in the largest multi-hospital systems. Our data show that hospital prices in California grew substantially (+76% per hospital admission across all hospitals and all services between 2004 and 2013 and that prices at hospitals that are members of the largest, multi-hospital systems grew substantially more (113% than prices paid to all other California hospitals (70%. Prices were similar in both groups at the start of the period (approximately $9200 per admission. By the end of the period, prices at hospitals in the largest systems exceeded prices at other California hospitals by almost $4000 per patient admission. Our study findings are potentially useful to policy makers across the country for several reasons. Our data measure actual prices for a large sample of hospitals over a long period of time in California. California experienced its wave of consolidation much earlier than the rest of the country and as such our findings may provide some insights into what may happen across the United States from hospital consolidation including growth of large, multi-hospital systems now forming in the rest of the rest of the country.

  8. Collaborative spectrum sensing based on the ratio between largest eigenvalue and Geometric mean of eigenvalues

    KAUST Repository

    Shakir, Muhammad

    2011-12-01

    In this paper, we introduce a new detector referred to as Geometric mean detector (GEMD) which is based on the ratio of the largest eigenvalue to the Geometric mean of the eigenvalues for collaborative spectrum sensing. The decision threshold has been derived by employing Gaussian approximation approach. In this approach, the two random variables, i.e. The largest eigenvalue and the Geometric mean of the eigenvalues are considered as independent Gaussian random variables such that their cumulative distribution functions (CDFs) are approximated by a univariate Gaussian distribution function for any number of cooperating secondary users and received samples. The approximation approach is based on the calculation of exact analytical moments of the largest eigenvalue and the Geometric mean of the eigenvalues of the received covariance matrix. The decision threshold has been calculated by exploiting the CDF of the ratio of two Gaussian distributed random variables. In this context, we exchange the analytical moments of the two random variables with the moments of the Gaussian distribution function. The performance of the detector is compared with the performance of the energy detector and eigenvalue ratio detector. Analytical and simulation results show that our newly proposed detector yields considerable performance advantage in realistic spectrum sensing scenarios. Moreover, our results based on proposed approximation approach are in perfect agreement with the empirical results. © 2011 IEEE.

  9. The global diversion of pharmaceutical drugs. India: the third largest illicit opium producer?

    Science.gov (United States)

    Paoli, Letizia; Greenfield, Victoria A; Charles, Molly; Reuter, Peter

    2009-03-01

    This paper explores India's role in the world illicit opiate market, particularly its role as a producer. India, a major illicit opiate consumer, is also the sole licensed exporter of raw opium: this unique status may be enabling substantial diversion to the illicit market. Participant observation and interviews were carried out at eight different sites. Information was also drawn from all standard secondary sources and the analysis of about 180 drug-related criminal proceedings reviewed by Indian High Courts and the Supreme Court from 1985 to 2001. Diversion from licit opium production takes place on such a large scale that India may be the third largest illicit opium producer after Afghanistan and Burma. With the possible exceptions of 2005 and 2006, 200-300 tons of India's opium may be diverted yearly. After estimating India's opiate consumption on the basis of UN-reported prevalence estimates, we find that diversion from licit production might have satisfied a quarter to more than a third of India's illicit opiate demand to 2004. India is not only among the world's largest consumer of illicit opiates but also one of the largest illicit opium producers. In contrast to all other illicit producers, India owes the latter distinction not to blatantly illicit cultivation but to diversion from licit cultivation. India's experience suggests the difficulty of preventing substantial leakage, even in a relatively well-governed nation.

  10. Paving the Way for Small Satellite Access to Orbit: Cyclops' Deployment of SpinSat, the Largest Satellite Ever Deployed from the International Space Station

    Science.gov (United States)

    Hershey, Matthew P.; Newswander, Daniel R.; Smith, James P.; Lamb, Craig R.; Ballard, Perry G.

    2015-01-01

    The Space Station Integrated Kinetic Launcher for Orbital Payload Systems (SSIKLOPS), known as "Cyclops" to the International Space Station (ISS) community, successfully deployed the largest satellite ever (SpinSat) from the ISS on November 28, 2014. Cyclops, a collaboration between the NASA ISS Program, NASA Johnson Space Center Engineering, and Department of Defense Space Test Program (DoD STP) communities, is a dedicated 10-100 kg class ISS small satellite deployment system. This paper will showcase the successful deployment of SpinSat from the ISS. It will also outline the concept of operations, interfaces, requirements, and processes for satellites to utilize the Cyclops satellite deployment system.

  11. Astronomers Break Ground on Atacama Large Millimeter Array (ALMA) - World's Largest Millimeter Wavelength Telescope

    Science.gov (United States)

    2003-11-01

    Scientists and dignitaries from Europe, North America and Chile are breaking ground today (Thursday, November 6, 2003) on what will be the world's largest, most sensitive radio telescope operating at millimeter wavelengths . ALMA - the "Atacama Large Millimeter Array" - will be a single instrument composed of 64 high-precision antennas located in the II Region of Chile, in the District of San Pedro de Atacama, at the Chajnantor altiplano, 5,000 metres above sea level. ALMA 's primary function will be to observe and image with unprecedented clarity the enigmatic cold regions of the Universe, which are optically dark, yet shine brightly in the millimetre portion of the electromagnetic spectrum. The Atacama Large Millimeter Array (ALMA) is an international astronomy facility. ALMA is an equal partnership between Europe and North America, in cooperation with the Republic of Chile, and is funded in North America by the U.S. National Science Foundation (NSF) in cooperation with the National Research Council of Canada (NRC), and in Europe by the European Southern Observatory (ESO) and Spain. ALMA construction and operations are led on behalf of North America by the National Radio Astronomy Observatory (NRAO), which is managed by Associated Universities, Inc. (AUI), and on behalf of Europe by ESO. " ALMA will be a giant leap forward for our studies of this relatively little explored spectral window towards the Universe" , said Dr. Catherine Cesarsky , Director General of ESO. "With ESO leading the European part of this ambitious and forward-looking project, the impact of ALMA will be felt in wide circles on our continent. Together with our partners in North America and Chile, we are all looking forward to the truly outstanding opportunities that will be offered by ALMA , also to young scientists and engineers" . " The U.S. National Science Foundation joins today with our North American partner, Canada, and with the European Southern Observatory, Spain, and Chile to prepare

  12. THE EVOLUTION OF THE WORLD’S LARGEST AUTOMAKERS IN THE PERIOD 2013-2014

    Directory of Open Access Journals (Sweden)

    Sorin-George TOMA

    2015-04-01

    Full Text Available The automotive industry has always represented an economic engine for many countries. It is dealing with the design, development, manufacture, marketing, and sale of the motor vehicles. Nowadays, this industry is full of intense competition between big auto groups fighting for higher profits and larger market shares. The key players in the automotive market are operating at a global scale in a highly competitive environment. In the last years, Toyota Motor and Volkswagen Group have proved to be the main competitors. The aim of our paper is to analyze the evolution of the world’s largest automakers in the period 2013-2014. The research type is literature review.

  13. Europe's largest solar thermal power plant. [200 kw thermal output supplemented by two 10-kw windmills

    Energy Technology Data Exchange (ETDEWEB)

    Bossel, U

    1976-03-01

    An overview is given over the solar heating plant which has recently been commissioned in the Camargue (France). This is the largest plant in Europe, with a mean heat output of about 200 kW, for the production of thermal energy from solar energy. The plant consists of 108 parabolic collectors (200 sq. metres) and 48 flat collectors (110 sq. metres). Two windmills with outputs of 10 kW each complete the system. The heat energy produced by the solar collectors is given up to 3 different stores, which in turn are connected to various consumers.

  14. OBJECT TRACKING WITH ROTATION-INVARIANT LARGEST DIFFERENCE INDEXED LOCAL TERNARY PATTERN

    Directory of Open Access Journals (Sweden)

    J Shajeena

    2017-02-01

    Full Text Available This paper presents an ideal method for object tracking directly in the compressed domain in video sequences. An enhanced rotation-invariant image operator called Largest Difference Indexed Local Ternary Pattern (LDILTP has been proposed. The Local Ternary Pattern which worked very well in texture classification and face recognition is now extended for rotation invariant object tracking. Histogramming the LTP code makes the descriptor resistant to translation. The histogram intersection is used to find the similarity measure. This method is robust to noise and retain contrast details. The proposed scheme has been verified on various datasets and shows a commendable performance.

  15. Female urethral diverticulum presenting with acute urinary retention: Reporting the largest diverticulum with review of literature

    Directory of Open Access Journals (Sweden)

    Manas Ranjan Pradhan

    2012-01-01

    Full Text Available Female urethral diverticulum is a rare entity with diverse spectrum of clinical manifestations. It is a very rare cause of bladder outlet obstruction and should be considered as a differential diagnosis in females presenting with acute urinary retention associated with a vaginal mass. Strong clinical suspicion combined with thorough physical examination and focused radiological investigations are vital for its diagnosis. Herein we report a case of giant urethral diverticulum presenting with acute urinary retention in a young female. It was managed by excision and urethral closure, and is the largest urethral diverticulum reported till date in the literature.

  16. WISMUT AG: Past, present and future of the largest uranium producer in Europe

    International Nuclear Information System (INIS)

    Madel, J.

    1990-01-01

    The author gives a brief summary of WISMUT AG the largest uranium producer operating in Europe. The jointly owned German-Soviet company operates its production facilities in the southern part of the former German Democratic Republic. Given the new political and economic frame in Germany and the Soviet Union WISMUT AG will receive due recognition. Uranium exploration, mining, and milling activities are summarized from 1946-1989, and a summary of present activities and projections of future activities in the area of decontamination, restoration, and recultivation of present and abandoned mining and milling sites are noted. A statement of WISMUT AG's projected role in the international nuclear fuels market is made

  17. How the largest electric and gas utility companies administer public relations

    Energy Technology Data Exchange (ETDEWEB)

    Bogart, J.D.

    1979-04-12

    This article describes the findings of a survey conducted by the author in the second half of 1978 to determine the sizes of the public relations staffs of the nation's largest operating electric and gas utilities, their budgets, organizational differences, and specific functions. Common public relations issues and major public relations problems of the utilities are identified, as well as recent trends or changes in budgeting and organization. Some functional variations of public relations departments among utility companies were detected and described.

  18. Line Balancing Using Largest Candidate Rule Algorithm In A Garment Industry: A Case Study

    Directory of Open Access Journals (Sweden)

    V. P.Jaganathan

    2014-12-01

    Full Text Available The emergence of fast changes in fashion has given rise to the need to shorten production cycle times in the garment industry. As effective usage of resources has a significant effect on the productivity and efficiency of production operations, garment manufacturers are urged to utilize their resources effectively in order to meet dynamic customer demand. This paper focuses specifically on line balancing and layout modification. The aim of assembly line balance in sewing lines is to assign tasks to the workstations, so that the machines of the workstation can perform the assigned tasks with a balanced loading. Largest Candidate Rule Algorithm (LCR has been deployed in this paper.

  19. Spatial Distribution of Market Centers

    Directory of Open Access Journals (Sweden)

    Md. Morshedul Islam

    2018-03-01

    Full Text Available The present study is an attempt to find the location pattern, distribution and their sphere of influences of market centers in Rangpur City Corporation, Bangladesh. Rangpur is facing some problems like a traffic jam, noisy environment, population pressure etc due to the over population in full day long in the center of this city, all of the whole sale and retail sale markets are located in the middle. Location of Market is always influencing the daily life of the city population who are directly or indirectly connected with the market. If the market strategically distributed in an area they don’t face such kind of problems. Analysis or investigation shows that at about all of the market centers are located in the center of Rangpur and in the residential area of Rangpur. The maximum 67% market centers are found in the high-income residential area. Rangpur City Corporation, Bangladesh Bureau of Statistics and survey of Bangladesh provided the maps, reports and relevant documents of the study. The spatial dispersion pattern of market centers is clustered together at one place 0.33(Nearest Neighbor Index value, R found in the study area. Geographical Information System (GIS and other software also used to analyze the maps and diagrams. Investigation refers that, the market of Rangpur city have a clustered pattern and different levels of market centers found on the bases of centrality scores. By this centrality scores or levels, found the variation of influencing spheres of market centers in Rangpur City.

  20. Foreign exchange risk management : how are the largest non-financial companies in Norway managing their foreign exchange rate exposure?

    OpenAIRE

    Eriksen, Krister; Wedøe, Ola

    2010-01-01

    The purpose of this thesis is to investigate how the largest non-financial companies in Norway manage their foreign exchange rate exposure. This is investigated through the use of a survey distributed to a sample the largest non-financial firms in Norway. According to our results, the largest non-financial companies in Norway have a predefined strategy for managing foreign exchange risk, which is defined by the board of directors or by the management in the organisation. The companies’ mai...

  1. Center for Adaptive Optics | Center

    Science.gov (United States)

    Astronomy, UCSC's CfAO and ISEE, and Maui Community College, runs education and internship programs in / Jacobs Retina Center Department of Psychology University of California, San Francisco Department of University School of Optometry Maui Community College Maui Community College Space Grant Program Montana

  2. Revisiting the impacts of oil price increases on monetary policy implementation in the largest oil importers

    Directory of Open Access Journals (Sweden)

    Nurtac Yildirim

    2015-06-01

    Full Text Available The aim of this paper is to test the impacts of oil price increases on monetary policy implementation in the largest oil importers. For that purpose, we estimate structural vector error correction (SVEC models to show the impacts of oil price increases on industrial production, consumer prices and immediate interest rates which are the elements of Taylor rule for the four largest oil importers (the USA, the EU, China and Japan. Our results indicate that oil price increases transmit to output and inflation and lead to fluctuations in industrial production, consumer prices and immediate interest rates which in turn influence the monetary policy stance in the following periods. The basic conclusion of research is that the channels through which oil prices affect output, inflation and interest rates should be identified by the monetary policy authorities of the USA, the EU, China and Japan. We also emphasize the importance of the determination of the optimal monetary policy framework to eliminate the negative consequences of oil price increases.

  3. Rehabilitation of the 6 largest hydropower plants in the Republic of Macedonia

    International Nuclear Information System (INIS)

    Chingoski, Vlatko; Savevski, Vasil

    2004-01-01

    In 1998, ESM (Electric Power Co. of Macedonia) received a loan from the International Bank for Reconstruction and Development (IBRD - The World bank) for the cost of the Power System Improvement Project, major part of which is the partial rehabilitation of the six largest HPPs in the Republic of Macedonia. Rehabilitation and life extension of these six largest hydro power plants is given the highest priority in the whole Power System Improvement Project mainly because these HPPs are, in general, fairly old, older than most of the thermal generation capacity and because a significant part of their equipment is wearing out, or is now obsolete with spare parts difficult to obtain. Furthermore, these plants play a vital role in the Macedonian Power System, providing peaking capacity, reserve capacity and frequency control. With the realization of this project, greater hydropower production is expected. It is also expected that HPPs will become a more vital part of the Macedonian Power System, which is also beneficial from an environmental aspect, due to greater usage of renewable energy resources in the country. (Original)

  4. Ownership structure and economic and socio-environmental disclosure in the largest Brazilian companies

    Directory of Open Access Journals (Sweden)

    Tatiana Aquino Almeida

    2016-01-01

    Full Text Available The disclosure of sustainable practices has become important in the search for competitive advantage, so as to meet the expectations of the various stakeholders. Thus, the study aims to investigate the relationship between the ownership structure and the economic and environmental voluntary disclosure in the largest Brazilian companies, analyzing ownership concentration and the identity of the controlling shareholder. For the analysis, we considered the economic, social and environmental perspectives, addressed both individually and jointly. The sample consists of 47 companies from the 100 largest public companies listed on BM&FBOVESPA, according to the magazine Exame Biggest and Best, edition 2013. The research is descriptive and quantitative, using Multiple Linear Regression for statistical analysis. The descriptive analysis of the prospects of (economic, social, environmental and sustainability disclosure showed lower average disclosure for the environmental aspect. The state control organizations stood out with the highest average in three of the four levels of disclosure: economic, social and sustainability. As regards the application of statistical analysis, the regression models were not statistically significant, indicating that, for the companies in the sample, the ownership structure does not influence the economic and socio-environmental disclosure.

  5. Assessment of microcystins in lake water and fish (Mugilidae, Liza sp.) in the largest Spanish coastal lake.

    Science.gov (United States)

    Romo, Susana; Fernández, Francisca; Ouahid, Youness; Barón-Sola, Ángel

    2012-01-01

    Cyanobacteria dominance and cyanotoxin production can become major threats to humans and aquatic life, especially in warm shallow lakes, which are often dominated by cyanobacteria. This study investigates the occurrence and distribution of microcystins (MCYST) in water, cell-bound and in the tissues of the commercial mugilid Liza sp. in the largest, coastal, Spanish Mediterranean lake (Albufera of Valencia). This is the first report concerning microcystin accumulation in tissues of mugilid fish species. Considerable amounts of microcystins were found in the water and seston, which correlated with development of Microcystis aeruginosa populations in the lake. The MCYST concentrations found in Lake Albufera (mean 1.7 and 17 μg/L and maximum 16 and 120 μg/L in water and seston, respectively) exceeded by one to two orders of magnitude the guideline levels proposed by the World Health Organization and were higher than that reported in other lakes of the Mediterranean zone. The presence of MCYST was found in all the fishes studied and accumulated differently among tissues of the commercial species Liza sp. Toxin accumulation in fish tissues showed that although the target organ for MCYST was the liver, high concentrations of microcystins were also found in other analysed tissues (liver>intestine>gills>muscle). Human tolerable daily intake for microcystins is assessed relative to the WHO guidelines, and potential toxicological risks for humans, wildlife and related ecosystems of the lake are discussed.

  6. Quantifying the potential for reservoirs to secure future surface water yields in the world’s largest river basins

    Science.gov (United States)

    Liu, Lu; Parkinson, Simon; Gidden, Matthew; Byers, Edward; Satoh, Yusuke; Riahi, Keywan; Forman, Barton

    2018-04-01

    Surface water reservoirs provide us with reliable water supply, hydropower generation, flood control and recreation services. Yet reservoirs also cause flow fragmentation in rivers and lead to flooding of upstream areas, thereby displacing existing land-use activities and ecosystems. Anticipated population growth and development coupled with climate change in many regions of the globe suggests a critical need to assess the potential for future reservoir capacity to help balance rising water demands with long-term water availability. Here, we assess the potential of large-scale reservoirs to provide reliable surface water yields while also considering environmental flows within 235 of the world’s largest river basins. Maps of existing cropland and habitat conservation zones are integrated with spatially-explicit population and urbanization projections from the Shared Socioeconomic Pathways to identify regions unsuitable for increasing water supply by exploiting new reservoir storage. Results show that even when maximizing the global reservoir storage to its potential limit (∼4.3–4.8 times the current capacity), firm yields would only increase by about 50% over current levels. However, there exist large disparities across different basins. The majority of river basins in North America are found to gain relatively little firm yield by increasing storage capacity, whereas basins in Southeast Asia display greater potential for expansion as well as proportional gains in firm yield under multiple uncertainties. Parts of Europe, the United States and South America show relatively low reliability of maintaining current firm yields under future climate change, whereas most of Asia and higher latitude regions display comparatively high reliability. Findings from this study highlight the importance of incorporating different factors, including human development, land-use activities, and climate change, over a time span of multiple decades and across a range of different

  7. One last boom : Alberta's rapidly expanding oil mines may be the largest and messiest industrial projects in Canadian history

    International Nuclear Information System (INIS)

    Laird, G.

    2001-01-01

    The bitumen deposits of Alberta, 2.5 trillion barrels of oil, of which 300 billion are considered recoverable, represent the greatest single petroleum resources of the world, based on surface and subsurface calculations. Four deposits, covering an area the size of New Brunswick, are located in the area stretching from Cold Lake to Lloydminster (east of Edmonton), the upper reaches of the Athabasca River east to the Peace River. The largest by far is the Athabasca deposit in the vicinity of Fort McMurray, spread over 4.3 million hectares. The deposit is at the centre of the biggest industrial expansion witnessed by the province. Since 1996, 38 billion dollars worth of new projects have been announced. It is estimated that by 2025, the bulk of the national oil production will originate from open-pit mines and underground wells around Fort McMurray. This oil boom has economic benefits for the population, from welders to real estate agents to stakeholders. The environmental effects are not as beneficial. Huge strip mines are being carved next to the Athabasca River, with great amounts of greenhouse gases emissions. The Suncor and Syncrude oil-sands plants combined represent the fourth largest carbon dioxide emission source in Canada. The development of these projects dramatically affects global warming. The nitrogen and sulphur emissions could also acidify lakes and soil in the region. The Suncor mine resulted from the first boom to hit Fort McMurray in 1964. The Syncrude mine is the result of the second boom which took place in 1973. In 1996, Suncor installed a sulphur scrubber system that removes 95 per cent of sulphur dioxide from the electricity and steam-generation plant. Suncor also invested in various projects, such as wind-power, rainforest cultivation and biomass generation. The volume of pollution increases as the operations expand, even if operations are cleaner. If no new gains in pollution control are achieved, it is expected that by 2015, the total

  8. Population control II: The population establishment today.

    Science.gov (United States)

    Hartmann, B

    1997-01-01

    Although population assistance represents a relatively small share of official development assistance, it influences many other aspects of development planning. The organizations that comprise the population establishment have a common purpose--the reduction of population growth in the Third World--but they are not homogeneous and sometimes have conflicting goals and strategies. National governments, multilateral agencies, nongovernmental organizations, foundations, academic centers, and pressure groups all contribute to creating and sustaining what has become a virtual population control industry. Through scholarships, travel grants, awards, and favorable publicity, Third World elites have been encouraged to join the population establishment. The World Bank, the U.S. Agency for International Development, and the U.N. Fund for Population Activities have pursued explicit strategies for pressuring Third World governments to design and implement population policies, most recently in Africa.

  9. Field Note: Threatening Tonle Sap: Challenges for Southeast-Asia’s largest Freshwater Lake

    Directory of Open Access Journals (Sweden)

    Kuenzer, Claudia

    2013-09-01

    Full Text Available The Tonle Sap ecosystem in Cambodia is Southeast Asia’s largest freshwater lake; strongly impacted by the Mekong river flood pulse. The lake is home to exceptional biodiversity, and rural communities living in free floating villages on the lake and on its shores. The fragile niche ecosystems as well as the rural livelihoods of Tonle Sap are under severe threat. Overfishing, illegal wood harvesting, further resource exploitation, and water quality deterioration all impact the stability of the socio-ecological system of Tonle Sap. At the same time, expected flood pulse changes due to regulatory measures in the context of hydropower development upstream on the Mekong are a severe threat for Tonle Sap’s ecosystem stability. The area needs to shift into the focus of attention of national and international re-searchers, stakeholders, and decision makers, to find suitable pathways for a future sustainable development of this unique and pristine region.

  10. Fifteen Years of Operation at NASA's National Transonic Facility with the World's Largest Adjustable Speed Drive

    Science.gov (United States)

    Sydnor, George H.; Bhatia, Ram; Krattiger, Hansueli; Mylius, Justus; Schafer, D.

    2012-01-01

    In September 1995, a project was initiated to replace the existing drive line at NASA's most unique transonic wind tunnel, the National Transonic Facility (NTF), with a single 101 MW synchronous motor driven by a Load Commutated Inverter (LCI). This Adjustable Speed Drive (ASD) system also included a custom four-winding transformer, harmonic filter, exciter, switch gear, control system, and feeder cable. The complete system requirements and design details have previously been presented and published [1], as well as the commissioning and acceptance test results [2]. The NTF was returned to service in December 1997 with the new drive system powering the fan. Today, this installation still represents the world s largest horizontal single motor/drive combination. This paper describes some significant events that occurred with the drive system during the first 15 years of service. These noteworthy issues are analyzed and root causes presented. Improvements that have substantially increased the long term viability of the system are given.

  11. Approaching the largest ‘API’: extracting information from the Internet with Python

    Directory of Open Access Journals (Sweden)

    Jonathan E. Germann

    2018-02-01

    Full Text Available This article explores the need for libraries to algorithmically access and manipulate the world’s largest API: the Internet. The billions of pages on the ‘Internet API’ (HTTP, HTML, CSS, XPath, DOM, etc. are easily accessible and manipulable. Libraries can assist in creating meaning through the datafication of information on the world wide web. Because most information is created for human consumption, some programming is required for automated extraction. Python is an easy-to-learn programming language with extensive packages and community support for web page automation. Four packages (Urllib, Selenium, BeautifulSoup, Scrapy in Python can automate almost any web page for all sized projects. An example warrant data project is explained to illustrate how well Python packages can manipulate web pages to create meaning through assembling custom datasets.

  12. Quicksort, largest bucket, and min-wise hashing with limited independence

    DEFF Research Database (Denmark)

    Knudsen, Mathias Bæk Tejs; Stöckel, Morten

    2015-01-01

    Randomized algorithms and data structures are often analyzed under the assumption of access to a perfect source of randomness. The most fundamental metric used to measure how “random” a hash function or a random number generator is, is its independence: a sequence of random variables is said...... to be k-independent if every variable is uniform and every size k subset is independent. In this paper we consider three classic algorithms under limited independence. Besides the theoretical interest in removing the unrealistic assumption of full independence, the work is motivated by lower independence...... being more practical. We provide new bounds for randomized quicksort, min-wise hashing and largest bucket size under limited independence. Our results can be summarized as follows. Randomized Quicksort. When pivot elements are computed using a 5-independent hash function, Karloff and Raghavan, J.ACM’93...

  13. Contamination Control Assessment of the World's Largest Space Environment Simulation Chamber

    Science.gov (United States)

    Snyder, Aaron; Henry, Michael W.; Grisnik, Stanley P.; Sinclair, Stephen M.

    2012-01-01

    The Space Power Facility s thermal vacuum test chamber is the largest chamber in the world capable of providing an environment for space simulation. To improve performance and meet stringent requirements of a wide customer base, significant modifications were made to the vacuum chamber. These include major changes to the vacuum system and numerous enhancements to the chamber s unique polar crane, with a goal of providing high cleanliness levels. The significance of these changes and modifications are discussed in this paper. In addition, the composition and arrangement of the pumping system and its impact on molecular back-streaming are discussed in detail. Molecular contamination measurements obtained with a TQCM and witness wafers during two recent integrated system tests of the chamber are presented and discussed. Finally, a concluding remarks section is presented.

  14. What could we learn about high energy particle physics from cosmological observations at largest spatial scales ?

    Directory of Open Access Journals (Sweden)

    Gorbunov Dmitry

    2017-01-01

    Full Text Available The very well known example of cosmology testing particle physics is the number of relativistic particles (photons and three active neutrinos within the Standard Model at primordial nucleosynthesis. These days the earliest moment we can hope to probe with present cosmological data is the early time inflation. The particle physics conditions there and now are different because of different energy scales and different values of the scalar fields, that usually prohibits a reliable connection between the particle physics parameters at the two interesting epochs. The physics at the highest energy scales may be probed with observations at the largest spatial scales (just somewhat smaller than the size of the visible Universe. However, we are not (yet ready to make the tests realistic, because of lack of a self-consistent theoretical description of the presently favorite cosmological models to be valid right after inflation.

  15. The role and attributes of entrepreneurs at South Africa´s largest arts festival

    Directory of Open Access Journals (Sweden)

    E. Jonker

    2009-01-01

    Full Text Available The Klein Karoo National Arts Festival (KKNK in Oudtshoorn, South Africa, is the largest arts festival in South Africa. The purpose of this research was to determine the attributes and role of the entrepreneurs at the Klein Karoo National Arts Festival. This was done by means of a questionnaire survey (N=249. After data capturing was completed, two factor analyses were conducted. The first factor analysis revealed six factors (entrepreneurial attributes, namely organisational skills, resourcefulness, self-edification, explorative, acquired skill and drive, of which resourcefulness had the highest mean value. The second factor analysis identified the role of entrepreneurs at KKNK and revealed three primary roles, namely festival promotion, product promotion and income generation, of which product promotion had the highest mean value. This is the first time that the roles of entrepreneurs at festivals were investigated in South Africa.

  16. EVALUATION OF E-RECRUITMENT LEVEL AMONG THE LARGEST COMPANIES IN POLAND - PROJECT OF RESEARCH

    Directory of Open Access Journals (Sweden)

    Dorota Buchnowska

    2015-12-01

    Full Text Available The changes taking place in the labor market cause that it is increasingly difficult to recruit employees with the right skills and competencies to companies. To reach the right candidates, they use modern IT solutions, such as ATS (Applicant Tracking System, which are supporting the processes of recruitment. Among others, they enable the publication of job offers on the Internet - on corporate websites, job portals and business social networking services - and apply for jobs online through these channels. This article pre-sents the evolution of the use of the Internet, and particularly the social media, in the recruitment process and presents a projekt of comprehensive research, which aims is to analyze and evaluate of the level of development of e-recruitment in Poland among largest companies.

  17. Damage and protection cost curves for coastal floods within the 600 largest European cities

    Science.gov (United States)

    Prahl, Boris F.; Boettle, Markus; Costa, Luís; Kropp, Jürgen P.; Rybski, Diego

    2018-01-01

    The economic assessment of the impacts of storm surges and sea-level rise in coastal cities requires high-level information on the damage and protection costs associated with varying flood heights. We provide a systematically and consistently calculated dataset of macroscale damage and protection cost curves for the 600 largest European coastal cities opening the perspective for a wide range of applications. Offering the first comprehensive dataset to include the costs of dike protection, we provide the underpinning information to run comparative assessments of costs and benefits of coastal adaptation. Aggregate cost curves for coastal flooding at the city-level are commonly regarded as by-products of impact assessments and are generally not published as a standalone dataset. Hence, our work also aims at initiating a more critical discussion on the availability and derivation of cost curves. PMID:29557944

  18. Using largest Lyapunov exponent to confirm the intrinsic stability of boiling water reactors

    International Nuclear Information System (INIS)

    Gavilian-Moreno, Carlos; Espinosa-Paredes, Gilberto

    2016-01-01

    The aim of this paper is the study of instability state of boiling water reactors with a method based in largest Lyapunov exponents (LLEs). Detecting the presence of chaos in a dynamical system is an important problem that is solved by measuring the LLE. Lyapunov exponents quantify the exponential divergence of initially close state-space trajectories and estimate the amount of chaos in a system. This method was applied to a set of signals from several nuclear power plant (NPP) reactors under commercial operating conditions that experienced instabilities events, apparently each of a different nature. Laguna Verde and Forsmark NPPs with in-phase instabilities, and Cofrentes NPP with out-of-phases instability. This study presents the results of intrinsic instability in the boiling water reactors of three NPPs. In the analyzed cases the limit cycle was not reached, which implies that the point of equilibrium exerts influence and attraction on system evolution

  19. Using largest Lyapunov exponent to confirm the intrinsic stability of boiling water reactors

    Energy Technology Data Exchange (ETDEWEB)

    Gavilian-Moreno, Carlos [Iberdrola Generacion, S.A., Cofrentes Nuclear Power Plant, Project Engineering Department, Paraje le Plano S/N, Valencia (Spain); Espinosa-Paredes, Gilberto [Area de ingeniera en Recursos Energeticos, Universidad Autonoma Metropolitana-Iztapalapa, Mexico city (Mexico)

    2016-04-15

    The aim of this paper is the study of instability state of boiling water reactors with a method based in largest Lyapunov exponents (LLEs). Detecting the presence of chaos in a dynamical system is an important problem that is solved by measuring the LLE. Lyapunov exponents quantify the exponential divergence of initially close state-space trajectories and estimate the amount of chaos in a system. This method was applied to a set of signals from several nuclear power plant (NPP) reactors under commercial operating conditions that experienced instabilities events, apparently each of a different nature. Laguna Verde and Forsmark NPPs with in-phase instabilities, and Cofrentes NPP with out-of-phases instability. This study presents the results of intrinsic instability in the boiling water reactors of three NPPs. In the analyzed cases the limit cycle was not reached, which implies that the point of equilibrium exerts influence and attraction on system evolution.

  20. World's largest off-road tires to be recycled

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2005-07-01

    Suncor Energy is the first company in Canada to use a new technology designed uniquely for tire recycling at oil sand facilities. The technology is owned by CuttingEdge Tire Recycling, a partnership between Denesoline Environmental Limited Partnership and Beaver Environmental Rubber Technologies Limited. Suncor has supported the development of this Aboriginal-owned and operated business by offering land, electricity, diesel fuel and stockpiles of used truck tires from its oil sand mining activities. These tires are the largest off-road tires in the world. In this new technology, tires that are worn-out through oil sand mining are shredded in a portable shredder before being recycled for subsequent use by the Alberta Recycling Management Association. 1 fig.

  1. A marine heatwave drives massive losses from the world’s largest seagrass carbon stocks

    KAUST Repository

    Arias-Ortiz, A.

    2018-03-29

    Seagrass ecosystems contain globally significant organic carbon (C) stocks. However, climate change and increasing frequency of extreme events threaten their preservation. Shark Bay, Western Australia, has the largest C stock reported for a seagrass ecosystem, containing up to 1.3% of the total C stored within the top metre of seagrass sediments worldwide. On the basis of field studies and satellite imagery, we estimate that 36% of Shark Bay’s seagrass meadows were damaged following a marine heatwave in 2010/2011. Assuming that 10 to 50% of the seagrass sediment C stock was exposed to oxic conditions after disturbance, between 2 and 9 Tg CO could have been released to the atmosphere during the following three years, increasing emissions from land-use change in Australia by 4–21% per annum. With heatwaves predicted to increase with further climate warming, conservation of seagrass ecosystems is essential to avoid adverse feedbacks on the climate system.

  2. Damage and protection cost curves for coastal floods within the 600 largest European cities

    Science.gov (United States)

    Prahl, Boris F.; Boettle, Markus; Costa, Luís; Kropp, Jürgen P.; Rybski, Diego

    2018-03-01

    The economic assessment of the impacts of storm surges and sea-level rise in coastal cities requires high-level information on the damage and protection costs associated with varying flood heights. We provide a systematically and consistently calculated dataset of macroscale damage and protection cost curves for the 600 largest European coastal cities opening the perspective for a wide range of applications. Offering the first comprehensive dataset to include the costs of dike protection, we provide the underpinning information to run comparative assessments of costs and benefits of coastal adaptation. Aggregate cost curves for coastal flooding at the city-level are commonly regarded as by-products of impact assessments and are generally not published as a standalone dataset. Hence, our work also aims at initiating a more critical discussion on the availability and derivation of cost curves.

  3. The largest deep-ocean silicic volcanic eruption of the past century.

    Science.gov (United States)

    Carey, Rebecca; Soule, S Adam; Manga, Michael; White, James; McPhie, Jocelyn; Wysoczanski, Richard; Jutzeler, Martin; Tani, Kenichiro; Yoerger, Dana; Fornari, Daniel; Caratori-Tontini, Fabio; Houghton, Bruce; Mitchell, Samuel; Ikegami, Fumihiko; Conway, Chris; Murch, Arran; Fauria, Kristen; Jones, Meghan; Cahalan, Ryan; McKenzie, Warren

    2018-01-01

    The 2012 submarine eruption of Havre volcano in the Kermadec arc, New Zealand, is the largest deep-ocean eruption in history and one of very few recorded submarine eruptions involving rhyolite magma. It was recognized from a gigantic 400-km 2 pumice raft seen in satellite imagery, but the complexity of this event was concealed beneath the sea surface. Mapping, observations, and sampling by submersibles have provided an exceptionally high fidelity record of the seafloor products, which included lava sourced from 14 vents at water depths of 900 to 1220 m, and fragmental deposits including giant pumice clasts up to 9 m in diameter. Most (>75%) of the total erupted volume was partitioned into the pumice raft and transported far from the volcano. The geological record on submarine volcanic edifices in volcanic arcs does not faithfully archive eruption size or magma production.

  4. A general scaling law reveals why the largest animals are not the fastest.

    Science.gov (United States)

    Hirt, Myriam R; Jetz, Walter; Rall, Björn C; Brose, Ulrich

    2017-08-01

    Speed is the fundamental constraint on animal movement, yet there is no general consensus on the determinants of maximum speed itself. Here, we provide a general scaling model of maximum speed with body mass, which holds across locomotion modes, ecosystem types and taxonomic groups. In contrast to traditional power-law scaling, we predict a hump-shaped relationship resulting from a finite acceleration time for animals, which explains why the largest animals are not the fastest. This model is strongly supported by extensive empirical data (474 species, with body masses ranging from 30 μg to 100 tonnes) from terrestrial as well as aquatic ecosystems. Our approach unravels a fundamental constraint on the upper limit of animal movement, thus enabling a better understanding of realized movement patterns in nature and their multifold ecological consequences.

  5. Largest solar installation on a hotel in Switzerland; Groesste Hotel-Solaranlage der Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Stadelmann, M.

    2008-07-01

    This article describes the solar thermal installation on the Hotel Europa in St. Moritz-Champfer, Switzerland. The installation provides heat energy for domestic hot water preparation and for the heating of the hotel's indoor swimming pool. A thirty-percent reduction of heating oil consumption has been obtained. The system, which is based on the 'low-flow' principle, provides the highest possible temperature difference while using low pumping energy. The hotel's hot-water circulation system, which ensures fast availability of hot water at the taps, is also discussed. This largest hotel solar installation is designed to meet heating and hot-water requirements during the summer season. The high requirements placed on the materials used are discussed. Schematics are provided and first operational experience is briefly discussed.

  6. Using Largest Lyapunov Exponent to Confirm the Intrinsic Stability of Boiling Water Reactors

    Directory of Open Access Journals (Sweden)

    Carlos J. Gavilán-Moreno

    2016-04-01

    Full Text Available The aim of this paper is the study of instability state of boiling water reactors with a method based in largest Lyapunov exponents (LLEs. Detecting the presence of chaos in a dynamical system is an important problem that is solved by measuring the LLE. Lyapunov exponents quantify the exponential divergence of initially close state-space trajectories and estimate the amount of chaos in a system. This method was applied to a set of signals from several nuclear power plant (NPP reactors under commercial operating conditions that experienced instabilities events, apparently each of a different nature. Laguna Verde and Forsmark NPPs with in-phase instabilities, and Cofrentes NPP with out-of-phases instability. This study presents the results of intrinsic instability in the boiling water reactors of three NPPs. In the analyzed cases the limit cycle was not reached, which implies that the point of equilibrium exerts influence and attraction on system evolution.

  7. From Pushing Paper to Pushing Dirt - Canada's Largest LLRW Cleanup Gets Underway - 13111

    International Nuclear Information System (INIS)

    Veen, Walter van; Lawrence, Dave

    2013-01-01

    The Port Hope Project is the larger of the two projects in the Port Hope Area Initiative (PHAI), Canada's largest low level radioactive waste (LLRW) cleanup. With a budget of approximately $1 billion, the Port Hope Project includes a broad and complex range of remedial elements from a state of the art water treatment plant, an engineered waste management facility, municipal solid waste removal, remediation of 18 major sites within the Municipality of Port Hope (MPH), sediment dredging and dewatering, an investigation of 4,800 properties (many of these homes) to identify LLRW and remediation of approximately 450 of these properties. This paper discusses the status of the Port Hope Project in terms of designs completed and regulatory approvals received, and sets out the scope and schedule for the remaining studies, engineering designs and remediation contracts. (authors)

  8. A marine heatwave drives massive losses from the world's largest seagrass carbon stocks

    Science.gov (United States)

    Arias-Ortiz, A.; Serrano, O.; Masqué, P.; Lavery, P. S.; Mueller, U.; Kendrick, G. A.; Rozaimi, M.; Esteban, A.; Fourqurean, J. W.; Marbà, N.; Mateo, M. A.; Murray, K.; Rule, M. J.; Duarte, C. M.

    2018-04-01

    Seagrass ecosystems contain globally significant organic carbon (C) stocks. However, climate change and increasing frequency of extreme events threaten their preservation. Shark Bay, Western Australia, has the largest C stock reported for a seagrass ecosystem, containing up to 1.3% of the total C stored within the top metre of seagrass sediments worldwide. On the basis of field studies and satellite imagery, we estimate that 36% of Shark Bay's seagrass meadows were damaged following a marine heatwave in 2010/2011. Assuming that 10 to 50% of the seagrass sediment C stock was exposed to oxic conditions after disturbance, between 2 and 9 Tg CO2 could have been released to the atmosphere during the following three years, increasing emissions from land-use change in Australia by 4-21% per annum. With heatwaves predicted to increase with further climate warming, conservation of seagrass ecosystems is essential to avoid adverse feedbacks on the climate system.

  9. Population parameters to compare dog breeds : differences between five Dutch purebred populations

    NARCIS (Netherlands)

    Nielen, A.L.J.; Beek, van der S.; Ubbink, G.J.; Knol, B.W.

    2001-01-01

    Differences in five purebred dog populations born in 1994 in the Netherlands were evaluated using different parameters. Numerically, the Golden Retriever was the largest breed (840 litters of 234 sires) and the Kooiker Dog (101 litters of 41 sires) the smallest. The litter per sire ratio was largest

  10. Mapping Biomass for REDD in the Largest Forest of Central Africa: the Democratic Republic of Congo

    Science.gov (United States)

    Shapiro, Aurelie; Saatchi, Sassan

    2014-05-01

    With the support of the International Climate Initiative (ICI) of the Federal Ministry of the Environment, Conservation, and Nuclear Security, the implementation of the German Development Bank KfW, the World Wide Fund for Nature (WWF) Germany, the University of California Los Angeles (UCLA) and local DRC partners will produce a national scale biomass map for the entire forest coverage of the Democratic Republic of Congo (DRC) along with feasibility assessments of different forest protection measures within a framework of a REDD+ model project. The « Carbon Map and Model (CO2M&M) » project will produce a national forest biomass map for the DRC, which will enable quantitative assessments of carbon stocks and emissions in the largest forest of the Congo Basin. This effort will support the national REDD (Reducing Emissions from Deforestation and Degradation) program in DRC, which plays a major role in sustainable development and poverty alleviation. This map will be developed from field data, complemented by airborne LiDAR (Light Detection and Ranging) and aerial photos, systematically sampled throughout the forests of the DRC and up-scaled to satellite images to accurately estimate carbon content in all forested areas. The second component of the project is to develop specific approaches for model REDD projects in key landscapes. This project represents the largest LiDAR-derived mapping effort in Africa, under unprecedented logistical constraints, which will provide one of the poorest nations in the world with the richest airborne and satellites derived datasets for analyzing forest structure, biomass and biodiversity.

  11. Dissolved Oxygen Dynamics in Backwaters of North America's Largest River Swamp

    Science.gov (United States)

    Bueche, S. M.; Xu, Y. J.; Reiman, J. H.

    2017-12-01

    The Atchafalaya River (AR) is the largest distributary of the Mississippi River flowing through south-central Louisiana, creating North America's largest river swamp basin - the Atchafalaya River Basin (ARB). Prior to human settlement, the AR's main channel was highly connected to this large wetland ecosystem. However, due to constructed levee systems and other human modifications, much of the ARB is now hydrologically disconnected from the AR's main channel except during high flow events. This lack of regular inputs of fresh, oxygenated water to these wetlands, paired with high levels of organic matter decomposition in wetlands, has caused low oxygen-deprived hypoxic conditions in the ARB's back waters. In addition, due to the incredibly nutrient-rich and warm nature of the ARB, microbial decomposition in backwater areas with limited flow often results in potentially stressful, if not lethal, levels of DO for organisms during and after flood pulses. This study aims to investigate dynamics of dissolved oxygen in backwaters of the Atchafalaya River Basin, intending to answer a crucial question about hydrological and water quality connectivity between the river's mainstem and its floodplain. Specifically, the study will 1) conduct field water quality measurements, 2) collect composite water samples for chemical analysis of nutrients and carbon, 3) investigate DO dynamics over different seasons for one year, and 4) determine the major factors that affect DO dynamics in this unique swamp ecosystem. The study is currently underway; therefore, in this presentation we will share the major findings gained in the past several months and discuss backwater effects on river chemistry.

  12. Is Kasei Valles (Mars) the largest volcanic channel in the solar system?

    Science.gov (United States)

    Leverington, David W.

    2018-02-01

    With a length of more than 2000 km and widths of up to several hundred kilometers, Kasei Valles is the largest outflow system on Mars. Superficially, the scabland-like character of Kasei Valles is evocative of terrestrial systems carved by catastrophic aqueous floods, and the system is widely interpreted as a product of outbursts from aquifers. However, as at other Martian outflow channels, clear examples of fluvial sedimentary deposits have proven difficult to identify here. Though Kasei Valles lacks several key properties expected of aqueous systems, its basic morphological and contextual properties are aligned with those of ancient volcanic channels on Venus, the Moon, Mercury, and Earth. There is abundant evidence that voluminous effusions of low-viscosity magmas occurred at the head of Kasei Valles, the channel system acted as a conduit for associated flows, and mare-style volcanic plains developed within its terminal basin. Combined mechanical and thermal incision rates of at least several meters per day are estimated to have been readily achieved at Kasei Valles by 20-m-deep magmas flowing with viscosities of 1 Pa s across low topographic slopes underlain by bedrock. If Kasei Valles formed through incision by magma, it would be the largest known volcanic channel in the solar system. The total volume of magma erupted at Kasei Valles is estimated here to have possibly reached or exceeded ∼5 × 106 km3, a volume comparable in magnitude to those that characterize individual Large Igneous Provinces on Earth. Development of other large outflow systems on Mars is expected to have similarly involved eruption of up to millions of cubic kilometers of magma.

  13. Implementation and evaluation of an algorithm-based order set for the outpatient treatment of urinary tract infections in the spinal cord injury population in a VA Medical Center.

    Science.gov (United States)

    Patros, Clayton; Sabol, Mirella; Paniagua, Angela; Lans, Daniel

    2018-03-01

    Treatment of urinary tract infections (UTI) in the spinal cord injury (SCI) population is often difficult due to the lack of symptoms, increased resistance, and increased morbidity and mortality associated with UTIs. To develop an algorithm-based order set for the treatment of UTIs for patients with SCI based on SCI-specific antibiogram data in order to assess and improve current antimicrobial prescribing practices at the Clement J. Zablocki Veterans Affairs Medical Center (ZVAMC). This study is a retrospective, pre- and post-implementation analysis of an order set based on SCI antibiogram data. Descriptive statistics were used to compare baseline data and characteristics and chi squared tests were used to evaluate the primary outcome and all secondary outcomes. To achieve a power of 80% with an effect size of 0.3, the goal was to assess 45 antimicrobial treatment courses in the pre-implementation group and 45 antimicrobial treatment courses in the post-implementation group. The percentage of appropriate antimicrobial treatment courses increased from 47.9% in the pre-intervention group (n = 73) to 71.8% in the post-intervention group (n = 39), which was statistically significant (P = 0.015). Patients with SCI treated for UTIs within the ZVAMC had a significantly higher percentage of appropriate treatment courses following the implementation of a unit-specific antibiogram, electronic order set, and educational in-service for providers. An order set and unit-specific antibiogram with related education may be beneficial in improving antimicrobial therapy from a stewardship perspective.

  14. The U.N. Population Fund: Background and the U.S. Funding Debate

    National Research Council Canada - National Science Library

    Blanchfield, Luisa

    2008-01-01

    The United Nations Population Fund (UNFPA), established in 1969, is the world's largest source of population and reproductive health programs and the principal unit within the United Nations for global population issues...

  15. The U.N. Population Fund: Background and the U.S. Funding Debate

    National Research Council Canada - National Science Library

    Blanchfield, Luisa

    2007-01-01

    The United Nations Population Fund (UNFPA), established in 1969, is the world's largest source of population and reproductive health programs and the principal unit within the United Nations for global population issues...

  16. Landscapes of thermal inequity: disproportionate exposure to urban heat in the three largest US cities

    Science.gov (United States)

    Mitchell, Bruce C.; Chakraborty, Jayajit

    2015-11-01

    Heat waves are the most significant cause of mortality in the US compared to other natural hazards. Prior studies have found increased heat exposure for individuals of lower socioeconomic status in several US cities, but few comparative analyses of the social distribution of urban heat have been conducted. To address this gap, our paper examines and compares the environmental justice consequences of urban heat risk in the three largest US cities: New York City, Los Angeles, and Chicago. Risk to urban heat is estimated on the basis of three characteristics of the urban thermal landscape: land surface temperature, vegetation abundance, and structural density of the built urban environment. These variables are combined to develop an urban heat risk index, which is then statistically compared with social vulnerability indicators representing socioeconomic status, age, disability, race/ethnicity, and linguistic isolation. The results indicate a consistent and significant statistical association between lower socioeconomic and minority status and greater urban heat risk, in all three cities. Our findings support a growing body of environmental justice literature that indicates the presence of a landscape of thermal inequity in US cities and underscores the need to conduct comparative analyses of social inequities in exposure to urban heat.

  17. KEPLER-1647B: THE LARGEST AND LONGEST-PERIOD KEPLER TRANSITING CIRCUMBINARY PLANET

    Energy Technology Data Exchange (ETDEWEB)

    Kostov, Veselin B. [NASA Goddard Space Flight Center, Mail Code 665, Greenbelt, MD 20771 (United States); Orosz, Jerome A.; Welsh, William F.; Short, Donald R. [Department of Astronomy, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182 (United States); Doyle, Laurance R. [SETI Institute, 189 Bernardo Avenue, Mountain View, CA 94043 (United States); Principia College, IMoP, One Maybeck Place, Elsah, IL 62028 (United States); Fabrycky, Daniel C. [Department of Astronomy and Astrophysics, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Haghighipour, Nader [Institute for Astronomy, University of Hawaii-Manoa, Honolulu, HI 96822 (United States); Quarles, Billy [Department of Physics and Physical Science, The University of Nebraska at Kearney, Kearney, NE 68849 (United States); Cochran, William D.; Endl, Michael [McDonald Observatory, The University of Texas as Austin, Austin, TX 78712-0259 (United States); Ford, Eric B. [Department of Astronomy and Astrophysics, The Pennsylvania State University, 428A Davey Lab, University Park, PA 16802 (United States); Gregorio, Joao [Atalaia Group and Crow-Observatory, Portalegre (Portugal); Hinse, Tobias C. [Korea Astronomy and Space Science Institute (KASI), Advanced Astronomy and Space Science Division, Daejeon 305-348 (Korea, Republic of); Isaacson, Howard [Department of Astronomy, University of California Berkeley, 501 Campbell Hall, Berkeley, CA 94720 (United States); Jenkins, Jon M. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Jensen, Eric L. N. [Department of Physics and Astronomy, Swarthmore College, Swarthmore, PA 19081 (United States); Kane, Stephen [Department of Physics and Astronomy, San Francisco State University, 1600 Holloway Avenue, San Francisco, CA 94132 (United States); Kull, Ilya, E-mail: veselin.b.kostov@nasa.gov [Department of Astronomy and Astrophysics, Tel Aviv University, 69978 Tel Aviv (Israel); and others

    2016-08-10

    We report the discovery of a new Kepler transiting circumbinary planet (CBP). This latest addition to the still-small family of CBPs defies the current trend of known short-period planets orbiting near the stability limit of binary stars. Unlike the previous discoveries, the planet revolving around the eclipsing binary system Kepler-1647 has a very long orbital period (∼1100 days) and was at conjunction only twice during the Kepler mission lifetime. Due to the singular configuration of the system, Kepler-1647b is not only the longest-period transiting CBP at the time of writing, but also one of the longest-period transiting planets. With a radius of 1.06 ± 0.01 R {sub Jup}, it is also the largest CBP to date. The planet produced three transits in the light curve of Kepler-1647 (one of them during an eclipse, creating a syzygy) and measurably perturbed the times of the stellar eclipses, allowing us to measure its mass, 1.52 ± 0.65 M {sub Jup}. The planet revolves around an 11-day period eclipsing binary consisting of two solar-mass stars on a slightly inclined, mildly eccentric ( e {sub bin} = 0.16), spin-synchronized orbit. Despite having an orbital period three times longer than Earth’s, Kepler-1647b is in the conservative habitable zone of the binary star throughout its orbit.

  18. Evidence for protection of targeted reef fish on the largest marine reserve in the Caribbean.

    Science.gov (United States)

    Pina-Amargós, Fabián; González-Sansón, Gaspar; Martín-Blanco, Félix; Valdivia, Abel

    2014-01-01

    Marine reserves can restore fish abundance and diversity in areas impacted by overfishing, but the effectiveness of reserves in developing countries where resources for enforcement are limited, have seldom been evaluated. Here we assess whether the establishment in 1996 of the largest marine reserve in the Caribbean, Gardens of the Queen in Cuba, has had a positive effect on the abundance of commercially valuable reef fish species in relation to neighboring unprotected areas. We surveyed 25 sites, including two reef habitats (reef crest and reef slope), inside and outside the marine reserve, on five different months, and over a one-and-a-half year period. Densities of the ten most frequent, highly targeted, and relatively large fish species showed a significant variability across the archipelago for both reef habitats that depended on the month of survey. These ten species showed a tendency towards higher abundance inside the reserve in both reef habitats for most months during the study. Average fish densities pooled by protection level, however, showed that five out of these ten species were at least two-fold significantly higher inside than outside the reserve at one or both reef habitats. Supporting evidence from previously published studies in the area indicates that habitat complexity and major benthic communities were similar inside and outside the reserve, while fishing pressure appeared to be homogeneous across the archipelago before reserve establishment. Although poaching may occur within the reserve, especially at the boundaries, effective protection from fishing was the most plausible explanation for the patterns observed.

  19. Scaling relationships among drivers of aquatic respiration from the smallest to the largest freshwater ecosystems

    Science.gov (United States)

    Hall, Ed K; Schoolmaster, Donald; Amado, A.M; Stets, Edward G.; Lennon, J.T.; Domaine, L.; Cotner, J.B.

    2016-01-01

    To address how various environmental parameters control or constrain planktonic respiration (PR), we used geometric scaling relationships and established biological scaling laws to derive quantitative predictions for the relationships among key drivers of PR. We then used empirical measurements of PR and environmental (soluble reactive phosphate [SRP], carbon [DOC], chlorophyll a [Chl-a)], and temperature) and landscape parameters (lake area [LA] and watershed area [WA]) from a set of 44 lakes that varied in size and trophic status to test our hypotheses. We found that landscape-level processes affected PR through direct effects on DOC and temperature and indirectly via SRP. In accordance with predictions made from known relationships and scaling laws, scale coefficients (the parameter that describes the shape of a relationship between 2 variables) were found to be negative and have an absolute value 1, others respiration from small pond catchments to the largest body of freshwater on the planet, Lake Superior, these findings should be applicable to controls of PR for the great majority of temperate aquatic ecosystems.

  20. Investigation of science faculty with education specialties within the largest university system in the United States.

    Science.gov (United States)

    Bush, Seth D; Pelaez, Nancy J; Rudd, James A; Stevens, Michael T; Tanner, Kimberly D; Williams, Kathy S

    2011-01-01

    Efforts to improve science education include university science departments hiring Science Faculty with Education Specialties (SFES), scientists who take on specialized roles in science education within their discipline. Although these positions have existed for decades and may be growing more common, few reports have investigated the SFES approach to improving science education. We present comprehensive data on the SFES in the California State University (CSU) system, the largest university system in the United States. We found that CSU SFES were engaged in three key arenas including K-12 science education, undergraduate science education, and discipline-based science education research. As such, CSU SFES appeared to be well-positioned to have an impact on science education from within science departments. However, there appeared to be a lack of clarity and agreement about the purpose of these SFES positions. In addition, formal training in science education among CSU SFES was limited. Although over 75% of CSU SFES were fulfilled by their teaching, scholarship, and service, our results revealed that almost 40% of CSU SFES were seriously considering leaving their positions. Our data suggest that science departments would likely benefit from explicit discussions about the role of SFES and strategies for supporting their professional activities.

  1. Sources and distribution of microplastics in China's largest inland lake - Qinghai Lake.

    Science.gov (United States)

    Xiong, Xiong; Zhang, Kai; Chen, Xianchuan; Shi, Huahong; Luo, Ze; Wu, Chenxi

    2018-04-01

    Microplastic pollution was studied in China's largest inland lake - Qinghai Lake in this work. Microplastics were detected with abundance varies from 0.05 × 10 5 to 7.58 × 10 5 items km -2 in the lake surface water, 0.03 × 10 5 to 0.31 × 10 5 items km -2 in the inflowing rivers, 50 to 1292 items m -2 in the lakeshore sediment, and 2 to 15 items per individual in the fish samples, respectively. Small microplastics (0.1-0.5 mm) dominated in the lake surface water while large microplastics (1-5 mm) are more abundant in the river samples. Microplastics were predominantly in sheet and fiber shapes in the lake and river water samples but were more diverse in the lakeshore sediment samples. Polymer types of microplastics were mainly polyethylene (PE) and polypropylene (PP) as identified using Raman Spectroscopy. Spatially, microplastic abundance was the highest in the central part of the lake, likely due to the transport of lake current. Based on the higher abundance of microplastics near the tourist access points, plastic wastes from tourism are considered as an important source of microplastics in Qinghai Lake. As an important area for wildlife conservation, better waste management practice should be implemented, and waste disposal and recycling infrastructures should be improved for the protection of Qinghai Lake. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. A study on the regionalization of tornadogenesis for the domestic largest scale of tornado

    International Nuclear Information System (INIS)

    Sugimoto, Soichiro; Nohara, Daisuke; Hirakuchi, Hiromaru

    2014-01-01

    A new regulatory guide has been issued by the Nuclear Regulation Authority of Japan since the last year. According to this guide, electric power companies have to assess the influence of tornadoes on their nuclear power plants for operation. The purpose of this study is to evaluate the likelihood of the occurrence of F3 tornadoes, which are the largest encountered in Japan, and to consider the possibility of the regionalization of the maximum wind speed. Then, mesoscale analysis with a numerical meteorological model and re-analysis data is performed along with synoptic scale analysis. Especially, tornado parameters such as SReH (Storm Relative Helicity) and CAPE (Convective Available Potential Energy) are used for evaluating the potential tornadogenesis of F3 tornado. Both analyses indicate that favorable meteorological condition tends to occur in the coastal zones in the Pacific side west of Ibaraki and around Kyushu island. The frequency in these zones is different from the one in the other area in the order of 1 or 2, which is large enough for regionalization. (author)

  3. Vascular access in lipoprotein apheresis: a retrospective analysis from the UK's largest lipoprotein apheresis centre.

    Science.gov (United States)

    Doherty, Daniel J; Pottle, Alison; Malietzis, George; Hakim, Nadey; Barbir, Mahmoud; Crane, Jeremy S

    2018-01-01

    Lipoprotein apheresis (LA) has proven to be an effective, safe and life-saving therapy. Vascular access is needed to facilitate this treatment but has recognised complications. Despite consistency in treatment indication and duration there are no guidelines in place. The aim of this study is to characterise vascular access practice at the UK's largest LA centre and forward suggestions for future approaches. A retrospective analysis of vascular access strategies was undertaken in all patients who received LA treatment in the low-density lipoprotein (LDL) Apheresis Unit at Harefield Hospital (Middlesex, UK) from November 2000 to March 2016. Fifty-three former and current patients underwent 4260 LA treatments. Peripheral vein cannulation represented 79% of initial vascular access strategies with arteriovenous (AV) fistula use accounting for 15%. Last used method of vascular access was peripheral vein cannulation in 57% versus AV fistula in 32%. Total AV fistula failure rate was 37%. Peripheral vein cannulation remains the most common method to facilitate LA. Practice trends indicate a move towards AV fistula creation; the favoured approach receiving support from the expert body in this area. AV fistula failure rate is high and of great concern, therefore we suggest the implementation of upper limb ultrasound vascular mapping in all patients who meet treatment eligibility criteria. We encourage close ties between apheresis units and specialist surgical centres to facilitate patient counselling and monitoring. Further prospective data regarding fistula failure is needed in this expanding treatment field.

  4. Sistema Faro, Isla de Mona, Puerto Rico: speleogenesis of the worlds largest flank margin cave

    International Nuclear Information System (INIS)

    Lace, M. J.; Kambesis, P. N.; Mylroie, J. E.

    2016-01-01

    Isla de Mona, a small, uplifted carbonate plateau jutting out of the waters of the Mona Passage, is an incredibly fragile and densely karstic environment. Expedition work was conducted by the Isla de Mona Project in cooperation with the Departamento Recursos Naturales y Ambientales de Puerto Rico (DRNA), including contributions from many researchers and cavers volunteering from across the U.S and Puerto Rico in the course of 12 separate expeditions, spanning a 14 year period (1998 to 2013). Over 200 caves have been documented on the island to date, the majority of this inventory is composed of flank margin caves but also includes sea caves, pit caves and talus caves. The most extensive example of cave development on the island is Sistema Faro - a sprawling maze-like series of chambers formed within the eastern point of the island with over 40 cliffside entrances overlooking the Caribbean Sea. Detailed cartography and analysis of the geomorphology and development of the Sistema Faro has helped form a complex model of carbonate island cave development as a function of tectonic uplift, lithology, sea level changes, karst hydrogeology and cliff retreat. This communication examines the roles these controls have played in the genesis of the world's largest flank margin cave. (Author)

  5. Stand Up for the Burrup: Saving the Largest Aboriginal Rock Art Precinct in Australia

    Directory of Open Access Journals (Sweden)

    Jenny Gregory

    2009-12-01

    Full Text Available The Dampier Rock Art Precinct contains the largest and most ancient collection of Aboriginal rock art in Australia. The cultural landscape created by generations of Aboriginal people includes images of long-extinct fauna and demonstrates the response of peoples to a changing climate over thousands of years as well as the continuity of lived experience. Despite Australian national heritage listing in 2007, this cultural landscape continues to be threatened by industrial development. Rock art on the eastern side of the archipelago, on the Burrup Peninsula, was relocated following the discovery of adjacent off-shore gas reserves so that a major gas plant could be constructed. Work has now begun on the construction of a second major gas plant nearby. This article describes the rock art of the Dampier Archipelago and the troubled history of European-Aboriginal contact history, before examining the impact of industry on the region and its environment. The destruction of Aboriginal rock art to meet the needs of industry is an example of continuing indifference to Aboriginal culture. While the complex struggle to protect the cultural landscape of the Burrup, in particular, involving Indigenous people, archaeologists, historians, state and federal politicians, government bureaucrats and multi-national companies, eventually led to national heritage listing, it is not clear that the battle to save the Burrup has been won.

  6. Percolation under noise: Detecting explosive percolation using the second-largest component

    Science.gov (United States)

    Viles, Wes; Ginestet, Cedric E.; Tang, Ariana; Kramer, Mark A.; Kolaczyk, Eric D.

    2016-05-01

    We consider the problem of distinguishing between different rates of percolation under noise. A statistical model of percolation is constructed allowing for the birth and death of edges as well as the presence of noise in the observations. This graph-valued stochastic process is composed of a latent and an observed nonstationary process, where the observed graph process is corrupted by type-I and type-II errors. This produces a hidden Markov graph model. We show that for certain choices of parameters controlling the noise, the classical (Erdős-Rényi) percolation is visually indistinguishable from a more rapid form of percolation. In this setting, we compare two different criteria for discriminating between these two percolation models, based on the interquartile range (IQR) of the first component's size, and on the maximal size of the second-largest component. We show through data simulations that this second criterion outperforms the IQR of the first component's size, in terms of discriminatory power. The maximal size of the second component therefore provides a useful statistic for distinguishing between different rates of percolation, under physically motivated conditions for the birth and death of edges, and under noise. The potential application of the proposed criteria for the detection of clinically relevant percolation in the context of applied neuroscience is also discussed.

  7. North Andean origin and diversification of the largest ithomiine butterfly genus

    Science.gov (United States)

    Lisa De-Silva, Donna; Mota, Luísa L.; Chazot, Nicolas; Mallarino, Ricardo; Silva-Brandão, Karina L.; Piñerez, Luz Miryam Gómez; Freitas, André V.L.; Lamas, Gerardo; Joron, Mathieu; Mallet, James; Giraldo, Carlos E.; Uribe, Sandra; Särkinen, Tiina; Knapp, Sandra; Jiggins, Chris D.; Willmott, Keith R.; Elias, Marianne

    2017-01-01

    The Neotropics harbour the most diverse flora and fauna on Earth. The Andes are a major centre of diversification and source of diversity for adjacent areas in plants and vertebrates, but studies on insects remain scarce, even though they constitute the largest fraction of terrestrial biodiversity. Here, we combine molecular and morphological characters to generate a dated phylogeny of the butterfly genus Pteronymia (Nymphalidae: Danainae), which we use to infer spatial, elevational and temporal diversification patterns. We first propose six taxonomic changes that raise the generic species total to 53, making Pteronymia the most diverse genus of the tribe Ithomiini. Our biogeographic reconstruction shows that Pteronymia originated in the Northern Andes, where it diversified extensively. Some lineages colonized lowlands and adjacent montane areas, but diversification in those areas remained scarce. The recent colonization of lowland areas was reflected by an increase in the rate of evolution of species’ elevational ranges towards present. By contrast, speciation rate decelerated with time, with no extinction. The geological history of the Andes and adjacent regions have likely contributed to Pteronymia diversification by providing compartmentalized habitats and an array of biotic and abiotic conditions, and by limiting dispersal between some areas while promoting interchange across others. PMID:28387233

  8. Level of patient and operator dose in the largest cardiac centre in Greece

    International Nuclear Information System (INIS)

    Tsapaki, V.; Patsilinakos, S.; Voudris, V.; Magginas, A.; Pavlidis, S.; Maounis, T.; Theodorakis, G.; Koutelou, M.; Vrantza, T.; Nearchou, M.; Nikolaki, N.; Kollaros, N.; Kyrozi, E.; Kottou, S.; Karaiskos, P.; Neofotistou, E.; Cokkinos, D.

    2008-01-01

    The objective of this study was to investigate the patient and staff doses in the most frequent interventional cardiology (IC) procedures performed in Onassio, the largest Cardiac Centre in Greece. Data were collected from three digital X-ray systems for 212 coronary angiographies, 203 percutaneous transluminal coronary angio-plasties (PTCA) and 134 various electrophysiological studies. Patient skin dose was measured using suitably calibrated slow radiotherapy films and cardiologist dose using suitably calibrated thermoluminescent dosemeters placed on left arm, hand and foot. Patient median dose area product (DAP) (all examinations) ranged between 6.7 and 83.5 Gy cm 2 . Patient median skin dose in PTCA was 799 mGy (320-1660 mGy) and in RF ablation 160 mGy (35-1920 mGy). Median arm, hand and foot dose to the cardiologist were 12.6, 27 and 13 μSv, respectively, per procedure. The great range of radiation doses received by both patients and operators confirms the need for continuous monitoring of all IC techniques. (authors)

  9. Bubble nucleation in simple and molecular liquids via the largest spherical cavity method

    International Nuclear Information System (INIS)

    Gonzalez, Miguel A.; Abascal, José L. F.; Valeriani, Chantal; Bresme, Fernando

    2015-01-01

    In this work, we propose a methodology to compute bubble nucleation free energy barriers using trajectories generated via molecular dynamics simulations. We follow the bubble nucleation process by means of a local order parameter, defined by the volume of the largest spherical cavity (LSC) formed in the nucleating trajectories. This order parameter simplifies considerably the monitoring of the nucleation events, as compared with the previous approaches which require ad hoc criteria to classify the atoms and molecules as liquid or vapor. The combination of the LSC and the mean first passage time technique can then be used to obtain the free energy curves. Upon computation of the cavity distribution function the nucleation rate and free-energy barrier can then be computed. We test our method against recent computations of bubble nucleation in simple liquids and water at negative pressures. We obtain free-energy barriers in good agreement with the previous works. The LSC method provides a versatile and computationally efficient route to estimate the volume of critical bubbles the nucleation rate and to compute bubble nucleation free-energies in both simple and molecular liquids

  10. Rise and Fall of one of World's largest deltas; the Mekong delta in Vietnam

    Science.gov (United States)

    Minderhoud, P. S. J.; Eslami Arab, S.; Pham, H. V.; Erkens, G.; van der Vegt, M.; Oude Essink, G.; Stouthamer, E.; Hoekstra, P.

    2017-12-01

    The Mekong delta is the third's largest delta in the world. It is home to almost 20 million people and an important region for the food security in South East Asia. As most deltas, the Mekong delta is the dynamic result of a balance of sediment supply, sea level rise and subsidence, hosting a system of fresh and salt water dynamics. Ongoing urbanization, industrialization and intensification of agricultural practices in the delta, during the past decades, resulted in growing domestic, agricultural and industrial demands, and have led to a dramatic increase of fresh water use. Since the year 2000, the amount of fresh groundwater extracted from the subsurface increased by 500%. This accelerated delta subsidence as the groundwater system compacts, with current sinking rates exceeding global sea level rise up to an order of magnitude. These high sinking rates have greatly altered the sediment budget of the delta and, with over 50% of the Mekong delta surface elevated less than 1 meter above sea level, greatly increase vulnerability to flooding and storm surges and ultimately, permanent inundation. Furthermore, as the increasingly larger extractions rapidly reduce the fresh groundwater reserves, groundwater salinization subsequently increases. On top of that, dry season low-flows by the Mekong river cause record salt water intrusion in the delta's estuarine system, creating major problems for rice irrigation. We present the work of three years research by the Dutch-Vietnamese `Rise and Fall' project on land subsidence and salinization in both groundwater and surface water in the Vietnamese Mekong delta.

  11. Mortgage loans: an analysis of the portfolios of the largest banks in Brazil

    Directory of Open Access Journals (Sweden)

    Bruno Vinícius Ramos Fernandes

    2013-05-01

    Full Text Available Given the current macroeconomic environment experienced in Brazil, where inflation has stabilized and the basic interest rate of the economy is in one of their historical lows, demand for mortgages is increasing. In this context, the mortgage is presented with great emphasis to meet the demand for purchasing housing in addition to being a catalyst for the reduction of the high housing deficit. From a descriptive and empirical-analytic was analyzed the mortgage loan portfolio of the largest banks of the country between the years 2001 and 2010 through Quarterly Financial Information (IFT available on the Central Bank website. It was settled a comparative relationship between the data in order to check the development of mortgage portfolios over the years and the factors that influenced this evolution, and evaluate the timeliness and quality of those loans. For the evolution of the portfolio there was an economic context in which Brazil was included in the period, and observed that for most of these operations are long term the banks are more exposed to market risk. With regard to credit risk parse that, over the years, Brazilian banks are presenting a mortgage loan portfolio with lower risk, and it is found that institutions with real estate credits with higher levels of portfolio risk are subject to have higher losses on such operations in the possibility of default.

  12. Corporate social responsibility of the 100 largest Indian companies – an analysis of website communication

    Directory of Open Access Journals (Sweden)

    Avinash Mulky

    2013-01-01

    Full Text Available Corporate social responsibility has become an important concept in the business world in recent decades. CSR is important in all countries but is particularly relevant in emerging markets where the levels of human development are not high. The United Nations Development Programme has created the Human Development Index (HDI to measure the human development in countries. The present study analyzes the CSR communication on the websites of the 100 largest Indian companies. The objective was to examine the reported CSR activities and determine whether the activities address the dimensions and indicators of the HDI. The study uses content analysis to classify the CSR activities into categories corresponding to HDI parameters. The findings indicate that about two thirds of the companies are using their websites to communicate CSR. Of the companies which reported CSR, about eighty percent report support for primary education and about seventy percent undertake livelihood support activities. The level of corporate involvement in the health dimension of human development is quite low. Reduction of infant and maternal mortality does not get much corporate attention. This study will add to the literature on CSR in emerging markets and will be useful for firms in India and other emerging markets that are planning CSR activities aimed at human development parameters.

  13. Natural radionuclides in soil profiles surrounding the largest coal-fired power plant in Serbia

    Directory of Open Access Journals (Sweden)

    Tanić Milan N.

    2016-01-01

    Full Text Available This study evaluates the influence of the largest Serbian coal-fired power plant on radionuclide concentrations in soil profiles up to 50 cm in depth. Thirty soil profiles were sampled from the plant surroundings (up to 10 km distance and analyzed using standard methods for soil physicochemical properties and gamma ray spectrometry for specific activities of natural radionuclides (40K, 226Ra and 232Th. Spatial and vertical distribution of radionuclides was determined and analyzed to show the relations between the specific activities in the soil and soil properties and the most influential factors of natural radionuclide variability were identified. The radiological indices for surface soil were calculated and radiological risk assessment was performed. The measured specific activities were similar to values of background levels for Serbia. The sampling depth did not show any significant influence on specific activities of natural radionuclides. The strongest predictor of specific activities of the investigated radionuclides was soil granulometry. All parameters of radiological risk assessment were below the recommended values and adopted limits. It appears that the coal-fired power plant does not have a significant impact on the spatial and vertical distribution of natural radionuclides in the area of interest, but technologically enhanced natural radioactivity as a consequence of the plant operations was identified within the first 1.5 km from the power plant. [Projekat Ministarstva nauke Republike Srbije br. III43009 i br. III41005

  14. Largest known Mesozoic multituberculate from Eurasia and implications for multituberculate evolution and biology.

    Science.gov (United States)

    Xu, Li; Zhang, Xingliao; Pu, Hanyong; Jia, Songhai; Zhang, Jiming; Lü, Junchang; Meng, Jin

    2015-10-22

    A new multituberculate, Yubaartar zhongyuanensis gen. and sp. nov., is reported from the Upper Cretaceous of Luanchuan County, Henan Province, China. The holotype of the new taxon is a partial skeleton with nearly complete cranium and associated lower jaws with in situ dentitions. The new species is the southern-most record of a Late Cretaceous multituberculate from outside of the Mongolian Plateau in Asia and represents the largest known Mesozoic multituberculate from Eurasia. The new specimen displays some intriguing features previously unknown in multituberculates, such as the first evidence of replacement of the ultimate upper premolar and a unique paleopathological case in Mesozoic mammals in which the animal with a severely broken right tibia could heal and survive in natural condition. The phylogenetic analysis based on craniodental characters places Yubaartar as the immediate outgroup of Taeniolabidoidea, a group consisting of a North American clade and an Asian clade. This relationship indicates at least a faunal interchange of multituberculates before the K-Pg transition. The new evidence further supports the hypothesis that disparity in dental complexity, which relates to animal diets, increased with generic richness and disparity in body size, and that an adaptive shift towards increased herbivory across the K-Pg transitional interval.

  15. Complex biogeographic scenarios revealed in the diversification of the largest woodpecker radiation in the New World.

    Science.gov (United States)

    Navarro-Sigüenza, Adolfo G; Vázquez-Miranda, Hernán; Hernández-Alonso, Germán; García-Trejo, Erick A; Sánchez-González, Luis A

    2017-07-01

    Phylogenetic relationships and patterns of evolution within Melanerpes, one of the most diverse groups of New World woodpeckers (22-23 lineages), have been complicated due to complex plumages and morphological adaptations. In an attempt to resolve these issues, we obtained sequence data from four nuclear introns and two mitochondrial protein-coding genes for 22 of the 24 currently recognized species in the genus. We performed phylogenetic analyses involving Maximum Likelihood and Bayesian Inference, species-tree divergence dating, and biogeographic reconstructions. Tree topologies from the concatenated and species-tree analyses of the mtDNA and nDNA showed broadly similar patterns, with three relatively well-supported groups apparent: (a) the Sphyrapicus clade (four species); (b) the typical Melanerpes clade, which includes temperate and subtropical dry forest black-backed species; and (c) the mostly barred-backed species, here referred to as the "Centurus" clade. The phylogenetic position of Melanerpes superciliaris regarding the rest of Melanerpes is ambiguous as it is recovered as sister to the rest of Melanerpes or as sister to a group including Sphyrapicus+Melanerpes. Our species tree estimations recovered the same well-delimited highly-supported clades. Geographic range evolution (estimated in BioGeoBEARS) was best explained by a DIVALIKE+j model, which includes vicariance, founder effect speciation, and anagenetic dispersal (range expansion) as important processes involved in the diversification of the largest radiation of woodpeckers in the New World. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Psyche's UV Reflectance Spectra: Exploring the origins of the largest exposed-core metallic asteroid

    Science.gov (United States)

    Becker, Tracy

    2016-10-01

    (16) Psyche is the largest of the M-class asteroids, and is presumed to be the exposed core of a differentiated asteroid stripped of its mantle through hit-and-run collisions. However, other origins for Psyche have been proposed, including that it formed from a highly-reduced, metal rich material in the inner solar system or that its surface is olivine that has been space weathered. If (16) Psyche is an exposed core, then studying its properties enhances our understanding of the cores of all terrestrial planets, including the Earth's. If it accreted in the inner part of the solar system and was later injected into the asteroid belt, then Psyche sheds light on the conditions and subsequent evolution of the early solar system. Lastly, if Psyche is weathered olivine, then olivine may be more abundant in the solar system than currently measured, rectifying the so-called Great Dunite Shortage. Our program to obtain high-resolution UV spectra of Psyche with the COS G140L mode and the STIS NUV MAMA G230L mode to measure spectral signatures between 90 - 315 nm is designed to distinguish between the 3 hypothesized cases. These observations will enable identification of absorption bands, especially Fe-O charge transfer bands and will be sensitive to spectral blueing that occurs at UV wavelengths for space-weathered objects. When combined, the presence of these UV features, or not, provides a novel test of Psyche formation theories.

  17. Carbon footprint of premium quality export bananas: case study in Ecuador, the world's largest exporter.

    Science.gov (United States)

    Iriarte, Alfredo; Almeida, Maria Gabriela; Villalobos, Pablo

    2014-02-15

    Nowadays, the new international market demands challenge the food producing countries to include the measurement of the environmental impact generated along the production process for their products. In order to comply with the environmentally responsible market requests the measurement of the greenhouse gas emissions of Ecuadorian agricultural goods has been promoted employing the carbon footprint concept. Ecuador is the largest exporter of bananas in the world. Within this context, this study is a first assessment of the carbon footprint of the Ecuadorian premium export banana (Musa AAA) using a considerable amount of field data. The system boundaries considered from agricultural production to delivery in a European destination port. The data collected over three years permitted identifying the hot spot stages. For the calculation, the CCaLC V3.0 software developed by the University of Manchester is used. The carbon footprint of the Ecuadorian export banana ranged from 0.45 to 1.04 kg CO2-equivalent/kg banana depending on the international overseas transport employed. The principal contributors to the carbon footprint are the on farm production and overseas transport stages. Mitigation and reduction strategies were suggested for the main emission sources in order to achieve sustainable banana production. Copyright © 2013 Elsevier B.V. All rights reserved.

  18. State-owned companies dominate list of largest non-U.S. producers

    International Nuclear Information System (INIS)

    Beck, R.J.; Williamson, M.

    1994-01-01

    Because state-owned oil and gas companies dominate Oil and Gas Journal's list of largest non-US producers, data aren't fully comparable with those of the OGJ300. Many state companies report only production and reserves, with little or no financial data. Companies on the OGJ100, therefore, cannot be ranked by assets or revenues. Instead, they are listed by regions, based on location of corporate headquarters. There was no change in makeup of the top 20 holders of crude oil reserves. These companies' reserves totaled 872.3 billion bbl in 1993. The top 20 non-US companies now control 87.3 % of total world crude oil reserves, according to OGJ estimates. This is up marginally from 87.2 % of total world oil reserves in 1992. The top 20 had 87.7 % of total world reserves in 1991 and 85.5 % in 1990. The table lists company name, total assets, revenues, net income, capital and exploratory expenditures, worldwide oil production, gas production, oil and gas reserves worldwide

  19. Estimation of the largest enterprises’ impact on the socio-economic development of territories

    Directory of Open Access Journals (Sweden)

    Ekaterina Dmitrievna Razgulina

    2014-07-01

    Full Text Available The key basic trends of modern society development are associated with the transfer of some government functions to big business. Thus, scientific and public circles argue about social partnership between government, business and employees and offer different variants of the corporate social responsibility concept. The article presents the experience to assess social responsibility of business on the example of the largest chemical enterprises located in the Vologda and Novgorod oblasts. The evaluation results have revealed a number of problems hindering the formation of socially responsible behavior of enterprises, particularly the lack of standardized reporting on corporate social responsibility; provision of formal corporate social responsibility report; business’ non-system participation in social and economic development of territories. According to the authors, the development of a special model to regulate participants’ mutual relations can increase social responsibility of Russian business. Unified interests and resources of business and government promote the development of an agreed strategy in the field of regional social-economic development

  20. Evaluation of several priority pollutants in zebra mussels (Dreissena polymorpha) in the largest Italian subalpine lakes

    International Nuclear Information System (INIS)

    Riva, Consuelo; Binelli, Andrea; Provini, Alfredo

    2008-01-01

    Zebra mussel (Dreissena polymorpha) has been used for the biomonitoring of several POPs (PCBs, DDTs, HCB and HCHs) in the largest Italian subalpine great lakes (Lake Maggiore, Garda, Como, Iseo and Lugano). Samplings were carried out in April 2003 at 15 locations selected according to industrial and anthropic levels of lakes. Results have pointed out high DDT levels in D. polymorpha specimens from Lake Maggiore (700-1400 ng/g lipids, 5-9 times higher than those measured in mussels of other Italian lakes), due to a contamination from a chemical plant located on one of the main lake inlet that occurred in 1996. On the contrary, PCB levels (400-2509 ng/g lipids) highlighted an overall pollution, with some sporadic peaks of contamination. Data showed a moderate increase trend compared to those found in a previous monitoring campaign carried out in 1996. Future monitoring is needed in order to confirm this tendency. - Significant levels of DDTs and PCBs are still present in the Italian subalpine great lakes

  1. Evaluation of several priority pollutants in zebra mussels (Dreissena polymorpha) in the largest Italian subalpine lakes

    Energy Technology Data Exchange (ETDEWEB)

    Riva, Consuelo [Department of Biology, Ecology Section, University of Milan, Via Celoria 26, 20133 Milan (Italy)], E-mail: consuelo.riva@unimi.it; Binelli, Andrea; Provini, Alfredo [Department of Biology, Ecology Section, University of Milan, Via Celoria 26, 20133 Milan (Italy)

    2008-02-15

    Zebra mussel (Dreissena polymorpha) has been used for the biomonitoring of several POPs (PCBs, DDTs, HCB and HCHs) in the largest Italian subalpine great lakes (Lake Maggiore, Garda, Como, Iseo and Lugano). Samplings were carried out in April 2003 at 15 locations selected according to industrial and anthropic levels of lakes. Results have pointed out high DDT levels in D. polymorpha specimens from Lake Maggiore (700-1400 ng/g lipids, 5-9 times higher than those measured in mussels of other Italian lakes), due to a contamination from a chemical plant located on one of the main lake inlet that occurred in 1996. On the contrary, PCB levels (400-2509 ng/g lipids) highlighted an overall pollution, with some sporadic peaks of contamination. Data showed a moderate increase trend compared to those found in a previous monitoring campaign carried out in 1996. Future monitoring is needed in order to confirm this tendency. - Significant levels of DDTs and PCBs are still present in the Italian subalpine great lakes.

  2. Monitoring coastal pollution associated with the largest oil refinery complex of Venezuela

    Directory of Open Access Journals (Sweden)

    Aldo Croquer

    2016-06-01

    Full Text Available This study evaluated pollution levels in water and sediments of Península de Paraguaná and related these levels with benthic macrofauna along a coastal area where the largest Venezuelan oil refineries have operated over the past 60 years. For this, the concentration of heavy metals, of hydrocarbon compounds and the community structure of the macrobenthos were examined at 20 sites distributed along 40 km of coastline for six consecutive years, which included windy and calm seasons. The spatial variability of organic and inorganic compounds showed considerably high coastal pollution along the study area, across both years and seasons. The southern sites, closest to the refineries, had consistently higher concentrations of heavy metals and organic compounds in water and sediments when compared to those in the north. The benthic community was dominated by polychaetes at all sites, seasons and years, and their abundance and distribution were significantly correlated with physical and chemical characteristics of the sediments. Sites close to the oil refineries were consistently dominated by families known to tolerate xenobiotics, such as Capitellidae and Spionidae. The results from this study highlight the importance of continuing long-term environmental monitoring programs to assess the impact of effluent discharge and spill events from the oil refineries that operate in the western coast of Paraguaná, Venezuela.

  3. Hydrodynamic and Inundation Modeling of China’s Largest Freshwater Lake Aided by Remote Sensing Data

    Directory of Open Access Journals (Sweden)

    Peng Zhang

    2015-04-01

    Full Text Available China’s largest freshwater lake, Poyang Lake, is characterized by rapid changes in its inundation area and hydrodynamics, so in this study, a hydrodynamic model of Poyang Lake was established to simulate these long-term changes. Inundation information was extracted from Moderate Resolution Imaging Spectroradiometer (MODIS remote sensing data and used to calibrate the wetting and drying parameter by assessing the accuracy of the simulated inundation area and its boundary. The bottom friction parameter was calibrated using current velocity measurements from Acoustic Doppler Current Profilers (ADCP. The results show the model is capable of predicting the inundation area dynamic through cross-validation with remotely sensed inundation data, and can reproduce the seasonal dynamics of the water level, and water discharge through a comparison with hydrological data. Based on the model results, the characteristics of the current velocities of the lake in the wet season and the dry season of the lake were explored, and the potential effect of the current dynamic on water quality patterns was discussed. The model is a promising basic tool for prediction and management of the water resource and water quality of Poyang Lake.

  4. Bedrock Canyons Carved by the Largest Known Floods on Earth and Mars

    Science.gov (United States)

    Lamb, M. P.; Lapôtre, M. G. A.; Larsen, I. J.; Williams, R. M. E.

    2017-12-01

    The surface of Earth is a dynamic and permeable interface where the rocky crust is sculpted by ice, wind and water resulting in spectacular mountain ranges, vast depositional basins and environments that support life. These landforms and deposits contain a rich, yet incomplete, record of Earth history that we are just beginning to understand. Some of the most dramatic landforms are the huge bedrock canyons carved by catastrophic floods. On Mars, similar bedrock canyons, known as Outflow Channels, are the most important indicators of large volumes of surface water in the past. Despite their importance and now decades of observations of canyon morphology, we lack a basic understanding of how the canyons formed, which limits our ability to reconstruct flood discharge, duration and water volume. In this presentation I will summarize recent work - using mechanistic numerical models and field observations - that suggests that bedrock canyons carved by megafloods rapidly evolve to a size and shape such that boundary shear stresses just exceed that required to entrain fractured blocks of rock. The threshold shear stress constraint allows for quantitative reconstruction of the largest known floods on Earth and Mars, and implies far smaller discharges than previous methods that assume flood waters fully filled the canyons to high water marks.

  5. KEPLER-1647B: THE LARGEST AND LONGEST-PERIOD KEPLER TRANSITING CIRCUMBINARY PLANET

    International Nuclear Information System (INIS)

    Kostov, Veselin B.; Orosz, Jerome A.; Welsh, William F.; Short, Donald R.; Doyle, Laurance R.; Fabrycky, Daniel C.; Haghighipour, Nader; Quarles, Billy; Cochran, William D.; Endl, Michael; Ford, Eric B.; Gregorio, Joao; Hinse, Tobias C.; Isaacson, Howard; Jenkins, Jon M.; Jensen, Eric L. N.; Kane, Stephen; Kull, Ilya

    2016-01-01

    We report the discovery of a new Kepler transiting circumbinary planet (CBP). This latest addition to the still-small family of CBPs defies the current trend of known short-period planets orbiting near the stability limit of binary stars. Unlike the previous discoveries, the planet revolving around the eclipsing binary system Kepler-1647 has a very long orbital period (∼1100 days) and was at conjunction only twice during the Kepler mission lifetime. Due to the singular configuration of the system, Kepler-1647b is not only the longest-period transiting CBP at the time of writing, but also one of the longest-period transiting planets. With a radius of 1.06 ± 0.01 R Jup , it is also the largest CBP to date. The planet produced three transits in the light curve of Kepler-1647 (one of them during an eclipse, creating a syzygy) and measurably perturbed the times of the stellar eclipses, allowing us to measure its mass, 1.52 ± 0.65 M Jup . The planet revolves around an 11-day period eclipsing binary consisting of two solar-mass stars on a slightly inclined, mildly eccentric ( e bin = 0.16), spin-synchronized orbit. Despite having an orbital period three times longer than Earth’s, Kepler-1647b is in the conservative habitable zone of the binary star throughout its orbit.

  6. Seasonal variations of trace elements in precipitation at the largest city in Tibet, Lhasa

    Science.gov (United States)

    Guo, Junming; Kang, Shichang; Huang, Jie; Zhang, Qianggong; Tripathee, Lekhendra; Sillanpää, Mika

    2015-02-01

    Precipitation samples were collected from March 2010 to August 2012 at an urban site in Lhasa, the capital and largest city of Tibet. The volume weighted mean (VWM) concentrations of 17 trace elements in precipitation were higher during the non-monsoon season than in the monsoon season, but inverse seasonal variations occurred for wet deposition fluxes of most of the trace elements. Concentrations for most of trace elements were negatively correlated with precipitation amount, indicating that below-cloud scavenging of trace elements was an important mechanism contributing to wet deposition of these elements. The elements Al, Sc, V, Cr, Mn, Fe, Mn, Ni, and U displayed low crustal enrichment factors (EFs), whereas Co, Cu, Zn, As, Cd Sn, Pb, and Bi showed high EF values in precipitation, suggesting that anthropogenic activities might be important contributors of these elements at Lhasa. However, this present work indicates a much lower anthropogenic emission at Lhasa than in seriously polluted regions. Our study will not only provide insights for assessing the current status of the atmospheric environment in Lhasa but also enhance our understanding for updating the baseline for environmental protection over the Tibetan Plateau.

  7. The largest subsea hot tap (future tap flange) at Angel Field, Australia

    Energy Technology Data Exchange (ETDEWEB)

    Lad, Deepak; Drysdale, Colin [T.D. Williamson (United States); Naidoo, Sashie [T.D. Williamson (Australia)

    2008-07-01

    A subsea hot tap was conducted near the gas production platforms in Angel Field, Australia in September 2007 and verified as the largest no. 900 subsea hot tap by Australian authorities. This paper outlines the subsea tapping process, risks and safety issues in deep water environment, including the need to ensure 100% system accuracy and that the machine fluids used to operate the subsea tapping machines were environmentally friendly. The testing phase included land and water testing. In the land tests, issues relating to metal hardness, temperature, pressure and ocean currents that affected machine stability, torque and cutting rate were considered. All preliminary design and testing focused on being able to mount the tapping machine to a pre-existing hot-tap flange and conduct the tapping operation, start to finish, preferably without changing the cutter. The water depth tests took place inside a pressurized, underwater hyperbaric chamber. The equipment repeated the land testing process in conditions duplicating that of the actual project site. Timing was also measured in multiple climatic conditions (except water depth) to obtain an estimation of various scenarios. The field tapping process was conducted without problems in over six hours with a single cutter and without any stalls. (author)

  8. Dragon bridge - the world largest dragon-shaped (ARCH steel bridge as element of smart city

    Directory of Open Access Journals (Sweden)

    Chinh Luong Minh

    2016-01-01

    Full Text Available Dragon Bridge - The world’s largest dragon-shaped steel bridge, with an installation cost of $85 million USD, features 6 lanes for two separate directions, 666 meters of undulating steel in the shape of a dragon in the Ly Dynasty, the symbol of prosperity in Vietnamese culture. This unique and beautifully lit bridge, which also breathes fire and sprays water. It’s the purposeful integration of the lighting hardware articulates the dragon’s form, and the fire-breathing dragon head. This project transcends the notion of monumental bridge with dynamic colour-changing lighting, creating an iconic sculpture in the skyline that is both reverent and whimsical. The signature feature of the bridge was the massive undulating support structure resembling a dragon flying over the river. The dragon is prominent in Vietnamese culture as a symbol of power and nobility. Dragon Bridge stands out as a model of innovation. It has received worldwide attention in the design community and from the global media for its unique arch support system. Dragon Bridge serves as an example of how aesthetic quality of a design can serve cultural, economic and functional purposes. The article presents design solutions of the object and the evaluation of the technical condition before putting the facility into service.

  9. Astronomer's new guide to the galaxy: largest map of cold dust revealed

    Science.gov (United States)

    2009-07-01

    Astronomers have unveiled an unprecedented new atlas of the inner regions of the Milky Way, our home galaxy, peppered with thousands of previously undiscovered dense knots of cold cosmic dust -- the potential birthplaces of new stars. Made using observations from the APEX telescope in Chile, this survey is the largest map of cold dust so far, and will prove an invaluable map for observations made with the forthcoming ALMA telescope, as well as the recently launched ESA Herschel space telescope. ESO PR Photo 24a/09 View of the Galactic Plane from the ATLASGAL survey (annotated and in five sections) ESO PR Photo 24b/09 View of the Galactic Plane from the ATLASGAL survey (annotated) ESO PR Photo 24c/09 View of the Galactic Plane from the ATLASGAL survey (in five sections) ESO PR Photo 24d/09 View of the Galactic Plane from the ATLASGAL survey ESO PR Photo 24e/09 The Galactic Centre and Sagittarius B2 ESO PR Photo 24f/09 The NGC 6357 and NGC 6334 nebulae ESO PR Photo 24g/09 The RCW120 nebula ESO PR Video 24a/09 Annotated pan as seen by the ATLASGAL survey This new guide for astronomers, known as the APEX Telescope Large Area Survey of the Galaxy (ATLASGAL) shows the Milky Way in submillimetre-wavelength light (between infrared light and radio waves [1]). Images of the cosmos at these wavelengths are vital for studying the birthplaces of new stars and the structure of the crowded galactic core. "ATLASGAL gives us a new look at the Milky Way. Not only will it help us investigate how massive stars form, but it will also give us an overview of the larger-scale structure of our galaxy", said Frederic Schuller from the Max Planck Institute for Radio Astronomy, leader of the ATLASGAL team. The area of the new submillimetre map is approximately 95 square degrees, covering a very long and narrow strip along the galactic plane two degrees wide (four times the width of the full Moon) and over 40 degrees long. The 16 000 pixel-long map was made with the LABOCA submillimetre

  10. Seasonal and Interannual Trends in Largest Cholera Endemic Megacity: Water Sustainability - Climate - Health Challenges in Dhaka, Bangladesh

    Science.gov (United States)

    Akanda, Ali S.; Jutla, Antarpreet; Faruque, Abu S. G.; Huq, Anwar; Colwell, Rita R.

    2014-05-01

    The last three decades of surveillance data shows a drastic increase of cholera prevalence in the largest cholera-endemic city in the world - Dhaka, Bangladesh. Emerging megacities in the region, especially those located in coastal areas also remain vulnerable to large scale drivers of cholera outbreaks. However, there has not been any systematic study on linking long-term disease trends with related changes in natural or societal variables. Here, we analyze the 30-year dynamics of urban cholera prevalence in Dhaka with changes in climatic or anthropogenic forcings: regional hydrology, flooding, water usage, changes in distribution systems, population growth and density in urban settlements, as well as shifting climate patterns and frequency of natural disasters. An interesting change is observed in the seasonal trends of cholera prevalence; while an endemic upward trend is seen in the dry season, the post-monsoon trend is epidemic in nature. In addition, the trend in the pre-monsoon dry season is significantly stronger than the post-monsoon wet season; and thus spring is becoming the dominant cholera season of the year. Evidence points to growing urbanization and rising population in unplanned settlements along the city peripheries. The rapid pressure of growth has led to an unsustainable and potentially disastrous situation with negligible-to-poor water and sanitation systems compounded by changing climatic patterns and increasing number of extreme weather events. Growing water scarcity in the dry season and lack of sustainable water and sanitation infrastructure for urban settlements have increased endemicity of cholera outbreaks in spring, while record flood events and prolonged post-monsoon inundation have contributed to increased epidemic outbreaks in fall. We analyze our findings with the World Health Organization recommended guidelines and investigate large scale water sustainability challenges in the context of climatic and anthropogenic changes in the

  11. Centered On The Pole: NCEI Interdisciplinary Arctic Data Stewardship

    Science.gov (United States)

    Zweng, M.

    2016-02-01

    In 2014, NOAA's data centers (National Climatic Data Center, National Oceanographic Data Center, National Geophysical Data Center and its affiliated program within the National Snow and Ice Data Center, and the National Coastal Data Development Center) merged to form NCEI, the National Centers for Environmental Information- the largest repository of publicly accessible earth system science data in the world. The merger has forced a reconciling of different workflows, data types, and cultures. However, the Arctic has emerged as a common area where the different centers can integrate their expertise, data assets, and services, and use this information to better align the entire organization. The centers face a unique challenge as they move forward: how to archive, steward and provide access to environmental data to fulfil their mission of providing the best information to help protect life and property. A pressing national need for information that supports policy decisions drives our work.

  12. Evidence for protection of targeted reef fish on the largest marine reserve in the Caribbean

    Directory of Open Access Journals (Sweden)

    Fabián Pina-Amargós

    2014-02-01

    Full Text Available Marine reserves can restore fish abundance and diversity in areas impacted by overfishing, but the effectiveness of reserves in developing countries where resources for enforcement are limited, have seldom been evaluated. Here we assess whether the establishment in 1996 of the largest marine reserve in the Caribbean, Gardens of the Queen in Cuba, has had a positive effect on the abundance of commercially valuable reef fish species in relation to neighboring unprotected areas. We surveyed 25 sites, including two reef habitats (reef crest and reef slope, inside and outside the marine reserve, on five different months, and over a one-and-a-half year period. Densities of the ten most frequent, highly targeted, and relatively large fish species showed a significant variability across the archipelago for both reef habitats that depended on the month of survey. These ten species showed a tendency towards higher abundance inside the reserve in both reef habitats for most months during the study. Average fish densities pooled by protection level, however, showed that five out of these ten species were at least two-fold significantly higher inside than outside the reserve at one or both reef habitats. Supporting evidence from previously published studies in the area indicates that habitat complexity and major benthic communities were similar inside and outside the reserve, while fishing pressure appeared to be homogeneous across the archipelago before reserve establishment. Although poaching may occur within the reserve, especially at the boundaries, effective protection from fishing was the most plausible explanation for the patterns observed.

  13. Phylogenetics and diversification of tanagers (Passeriformes: Thraupidae), the largest radiation of Neotropical songbirds.

    Science.gov (United States)

    Burns, Kevin J; Shultz, Allison J; Title, Pascal O; Mason, Nicholas A; Barker, F Keith; Klicka, John; Lanyon, Scott M; Lovette, Irby J

    2014-06-01

    Thraupidae is the second largest family of birds and represents about 4% of all avian species and 12% of the Neotropical avifauna. Species in this family display a wide range of plumage colors and patterns, foraging behaviors, vocalizations, ecotypes, and habitat preferences. The lack of a complete phylogeny for tanagers has hindered the study of this evolutionary diversity. Here, we present a comprehensive, species-level phylogeny for tanagers using six molecular markers. Our analyses identified 13 major clades of tanagers that we designate as subfamilies. In addition, two species are recognized as distinct branches on the tanager tree. Our topologies disagree in many places with previous estimates of relationships within tanagers, and many long-recognized genera are not monophyletic in our analyses. Our trees identify several cases of convergent evolution in plumage ornaments and bill morphology, and two cases of social mimicry. The phylogeny produced by this study provides a robust framework for studying macroevolutionary patterns and character evolution. We use our new phylogeny to study diversification processes, and find that tanagers show a background model of exponentially declining diversification rates. Thus, the evolution of tanagers began with an initial burst of diversification followed by a rate slowdown. In addition to this background model, two later, clade-specific rate shifts are supported, one increase for Darwin's finches and another increase for some species of Sporophila. The rate of diversification within these two groups is exceptional, even when compared to the overall rapid rate of diversification found within tanagers. This study provides the first robust assessment of diversification rates for the Darwin's finches in the context of the larger group within which they evolved. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Smart phone Acceptance among physicians: Application of structural equation modeling in Iranian largest university

    Directory of Open Access Journals (Sweden)

    Nematollahi M.

    2017-03-01

    Full Text Available Background: The present study aimed to determine attitudes and effective factors in the acceptance of smart phones by physicians of the largest University of Medical Sciences in the south of Iran. Methods: This cross-sectional study was performed using Structural Equation Modelling (SEM in 2014. Study participants included 200 physicians working in the hospitals of Shiraz University of Medical Sciences selected through two-stage stratified sampling, but 185 participants completed the study. The study data were collected using a researcher-made questionnaire completed through a 5-point Likert scale. The content validity of the questionnaire was confirmed by a panel of experts, its construct validity by confirmatory factor analysis, and its reliability by Cronbach’s alpha of 0.802. All data analyses were performed using SPSS (version 22 and LISREL (version 8.8. Results: Results showed that most physicians had a desirable attitude towards using smart phones. Besides, the results of SEM indicated a significant relationship between attitude and compatibility, observability, personal experience, voluntariness of use and perceived usefulness. Moreover, some important fitness indices revealed appropriate fitness of the study model (p=0.26, X2 /df=1.35, RMR=0.070, GFI=0.77, AGFI=0.71, NNFI=0.93, CFI=0.94. Conclusion: The results revealed that compatibility, observability, personal experience, voluntariness of use and perceived usefulness were effective in the physicians’ attitude towards using smart phones. Thus, by preparation of the required infrastructures, policymakers in the field of health technology can enhance the utilization of smart phones in hospitals.

  15. Negotiating place and gendered violence in Canada's largest open drug scene.

    Science.gov (United States)

    McNeil, Ryan; Shannon, Kate; Shaver, Laura; Kerr, Thomas; Small, Will

    2014-05-01

    Vancouver's Downtown Eastside is home to Canada's largest street-based drug scene and only supervised injection facility (Insite). High levels of violence among men and women have been documented in this neighbourhood. This study was undertaken to explore the role of violence in shaping the socio-spatial relations of women and 'marginal men' (i.e., those occupying subordinate positions within the drug scene) in the Downtown Eastside, including access to Insite. Semi-structured qualitative interviews were conducted with 23 people who inject drugs (PWID) recruited through the Vancouver Area Network of Drug Users, a local drug user organization. Interviews included a mapping exercise. Interview transcripts and maps were analyzed thematically, with an emphasis on how gendered violence shaped participants' spatial practices. Hegemonic forms of masculinity operating within the Downtown Eastside framed the everyday violence experienced by women and marginal men. This violence shaped the spatial practices of women and marginal men, in that they avoided drug scene milieus where they had experienced violence or that they perceived to be dangerous. Some men linked their spatial restrictions to the perceived 'dope quality' of neighbourhood drug dealers to maintain claims to dominant masculinities while enacting spatial strategies to promote safety. Environmental supports provided by health and social care agencies were critical in enabling women and marginal men to negotiate place and survival within the context of drug scene violence. Access to Insite did not motivate participants to enter into "dangerous" drug scene milieus but they did venture into these areas if necessary to obtain drugs or generate income. Gendered violence is critical in restricting the geographies of men and marginal men within the street-based drug scene. There is a need to scale up existing environmental interventions, including supervised injection services, to minimize violence and potential drug

  16. NEGOTIATING PLACE AND GENDERED VIOLENCE IN CANADA’S LARGEST OPEN DRUG SCENE

    Science.gov (United States)

    McNeil, Ryan; Shannon, Kate; Shaver, Laura; Kerr, Thomas; Small, Will

    2014-01-01

    Background Vancouver’s Downtown Eastside is home to Canada’s largest street-based drug scene and only supervised injection facility (Insite). High levels of violence among men and women have been documented in this neighbourhood. This study was undertaken to explore the role of violence in shaping the socio-spatial relations of women and ‘marginal men’ (i.e., those occupying subordinate positions within the drug scene) in the Downtown Eastside, including access to Insite. Methods Semi-structured qualitative interviews were conducted with 23 people who inject drugs (PWID) recruited through the Vancouver Area Network of Drug Users, a local drug user organization. Interviews included a mapping exercise. Interview transcripts and maps were analyzed thematically, with an emphasis on how gendered violence shaped participants’ spatial practices. Results Hegemonic forms of masculinity operating within the Downtown Eastside framed the everyday violence experienced by women and marginal men. This violence shaped the spatial practices of women and marginal men, in that they avoided drug scene milieus where they had experienced violence or that they perceived to be dangerous. Some men linked their spatial restrictions to the perceived 'dope quality' of neighbourhood drug dealers to maintain claims to dominant masculinities while enacting spatial strategies to promote safety. Environmental supports provided by health and social care agencies were critical in enabling women and marginal men to negotiate place and survival within the context of drug scene violence. Access to Insite did not motivate participants to enter into “dangerous” drug scene milieus but they did venture into these areas if necessary to obtain drugs or generate income. Conclusion Gendered violence is critical in restricting the geographies of men and marginal men within the street-based drug scene. There is a need to scale up existing environmental interventions, including supervised injection

  17. Geochemical characterization of the largest upland lake of the Brazilian Amazonia: Impact of provenance and processes

    Science.gov (United States)

    Sahoo, Prafulla Kumar; Guimarães, José Tasso Felix; Souza-Filho, Pedro Walfir Martins; da Silva, Marcio Sousa; Nascimento, Wilson, Júnior; Powell, Mike A.; Reis, Luiza Santos; Pessenda, Luiz Carlos Ruiz; Rodrigues, Tarcísio Magevski; da Silva, Delmo Fonseca; Costa, Vladimir Eliodoro

    2017-12-01

    Lake Três Irmãs (LTI), the largest upland lake in the Brazilian Amazonia, located in Serra dos Carajás, was characterized using multi-elemental and isotope geochemistry (δ13C and δ15N) to understand the significance of organic and inorganic sources, weathering and sedimentary processes on the distribution of elements in lake bottom (surficial) sediments. Carbon and nitrogen isotopes from sedimentary organic matter suggest C3 terrestrial plants (forests > canga vegetation), macrophytes and freshwater DOC as the main sources. Sediments are depleted in most of the major oxides (except Fe2O3 and P2O5) when compared to upper continental crust (UCC) and their spatial distribution is highly influenced by catchment lithology. Principal Component Analysis revealed that most of the trace elements (Ba, Sr, Rb, Sc, Th, U, Zr, Hf, Nb, Y, V, Cr, Ga, Co, Ni) and REEs are closely correlated with Al and Ti (PC1; Group-1), so their redistribution is less influenced by post-depositional process. This is due to their relative immobility and being hosted by Al-bearing minerals during laterization. High Chemical Index of Alteration (CIA), Mafic Index of Alteration (MIA) and Index of Laterization (IOL) values indicate intense chemical weathering at source areas, but the weathering transformation was better quantified by IOL. A-CN-K plot along with elemental ratios (Al/K, Ti/K, Ti/Zr, La/Al, Cr/Th, Co/Th, La/Sm, La/Gd, Zr/Y, and Eu/Eu*) as well as chondrite-normalized REE patterns show that the detritic sediments are mainly sourced from ferruginous laterites and soils in the catchment, which may have characteristics similar to mafic rocks.

  18. Effect of noise and filtering on largest Lyapunov exponent of time series associated with human walking.

    Science.gov (United States)

    Mehdizadeh, Sina; Sanjari, Mohammad Ali

    2017-11-07

    This study aimed to determine the effect of added noise, filtering and time series length on the largest Lyapunov exponent (LyE) value calculated for time series obtained from a passive dynamic walker. The simplest passive dynamic walker model comprising of two massless legs connected by a frictionless hinge joint at the hip was adopted to generate walking time series. The generated time series was used to construct a state space with the embedding dimension of 3 and time delay of 100 samples. The LyE was calculated as the exponential rate of divergence of neighboring trajectories of the state space using Rosenstein's algorithm. To determine the effect of noise on LyE values, seven levels of Gaussian white noise (SNR=55-25dB with 5dB steps) were added to the time series. In addition, the filtering was performed using a range of cutoff frequencies from 3Hz to 19Hz with 2Hz steps. The LyE was calculated for both noise-free and noisy time series with different lengths of 6, 50, 100 and 150 strides. Results demonstrated a high percent error in the presence of noise for LyE. Therefore, these observations suggest that Rosenstein's algorithm might not perform well in the presence of added experimental noise. Furthermore, findings indicated that at least 50 walking strides are required to calculate LyE to account for the effect of noise. Finally, observations support that a conservative filtering of the time series with a high cutoff frequency might be more appropriate prior to calculating LyE. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. The 100-C-7 Remediation Project. An Overview of One of DOE's Largest Remediation Projects - 13260

    International Nuclear Information System (INIS)

    Post, Thomas C.; Strom, Dean; Beulow, Laura

    2013-01-01

    The U.S. Department of Energy Richland Operations Office (RL), U.S. Environmental Protection Agency (EPA) and Washington Closure Hanford LLC (WCH) completed remediation of one of the largest waste sites in the U.S. Department of Energy complex. The waste site, 100-C-7, covers approximately 15 football fields and was excavated to a depth of 85 feet (groundwater). The project team removed a total of 2.3 million tons of clean and contaminated soil, concrete debris, and scrap metal. 100-C-7 lies in Hanford's 100 B/C Area, home to historic B and C Reactors. The waste site was excavated in two parts as 100-C-7 and 100-C-7:1. The pair of excavations appear like pit mines. Mining engineers were hired to design their tiered sides, with safety benches every 17 feet and service ramps which allowed equipment access to the bottom of the excavations. The overall cleanup project was conducted over a span of almost 10 years. A variety of site characterization, excavation, load-out and sampling methodologies were employed at various stages of remediation. Alternative technologies were screened and evaluated during the project. A new method for cost effectively treating soils was implemented - resulting in significant cost savings. Additional opportunities for minimizing waste streams and recycling were identified and effectively implemented by the project team. During the final phase of cleanup the project team applied lessons learned throughout the entire project to address the final, remaining source of chromium contamination. The C-7 cleanup now serves as a model for remediating extensive deep zone contamination sites at Hanford. (authors)

  20. HOT Faults", Fault Organization, and the Occurrence of the Largest Earthquakes

    Science.gov (United States)

    Carlson, J. M.; Hillers, G.; Archuleta, R. J.

    2006-12-01

    We apply the concept of "Highly Optimized Tolerance" (HOT) for the investigation of spatio-temporal seismicity evolution, in particular mechanisms associated with largest earthquakes. HOT provides a framework for investigating both qualitative and quantitative features of complex feedback systems that are far from equilibrium and punctuated by rare, catastrophic events. In HOT, robustness trade-offs lead to complexity and power laws in systems that are coupled to evolving environments. HOT was originally inspired by biology and engineering, where systems are internally very highly structured, through biological evolution or deliberate design, and perform in an optimum manner despite fluctuations in their surroundings. Though faults and fault systems are not designed in ways comparable to biological and engineered structures, feedback processes are responsible in a conceptually comparable way for the development, evolution and maintenance of younger fault structures and primary slip surfaces of mature faults, respectively. Hence, in geophysical applications the "optimization" approach is perhaps more aptly replaced by "organization", reflecting the distinction between HOT and random, disorganized configurations, and highlighting the importance of structured interdependencies that evolve via feedback among and between different spatial and temporal scales. Expressed in the terminology of the HOT concept, mature faults represent a configuration optimally organized for the release of strain energy; whereas immature, more heterogeneous fault networks represent intermittent, suboptimal systems that are regularized towards structural simplicity and the ability to generate large earthquakes more easily. We discuss fault structure and associated seismic response pattern within the HOT concept, and outline fundamental differences between this novel interpretation to more orthodox viewpoints like the criticality concept. The discussion is flanked by numerical simulations of a

  1. Iceland as the largest source of natural air pollution in the Arctic

    Science.gov (United States)

    Dagsson Waldhauserova, Pavla; Meinander, Outi; Olafsson, Haraldur; Arnalds, Olafur

    2017-04-01

    Arctic aerosols are often attributed to the Arctic Haze and long-range transport tracers. There is, however, an important dust source in the Arctic/Sub-arctic region which should receive more attention. The largest desert in the Arctic as well as in the Europe is Iceland with > 40,000 km2 of desert areas. The mean dust suspension frequency was 135 dust days annually in 1949-2012 with decreasing numbers in 2013-2015. The annual dust deposition was calculated as 31-40 million tons yr-1 affecting the area of > 500,000 km2. Satelite MODIS pictures have revealed dust plumes traveling > 1000 km at times. The physical properties of Icelandic dust showed differences in mineralogy, geochemical compositions, shapes, sizes, and colour, compared to the crustal mineral dust. Icelandic dust is of volcanic origin, dark in colour with sharp-tipped shards and large bubbles. About 80% of the particulate matter is volcanic glass rich in heavy metals, such as iron and titanium. Suspended dust measured at the glacial dust source consisted of such high number of close-to-ultrafine particles as concentrations during active eruptions. Generally, about 50% of the suspended PM10 are submicron particles in Iceland. Contrarily, suspended grains > 2 mm were captured during severe dust storm after the 2010 Eyjafjallajokull eruption when the aeolian transport exceeded 11 t m-1 of materials and placed this storms among the most extreme wind erosion events recorded on Earth. Our reflectance measurements showed that Icelandic dust deposited on snow lowers the snow albedo and reduces the snow density as much as Black Carbon. Icelandic volcanic dust tends to act as a positive climate forcing agent, both directly and indirectly, which is different to what generally concluded for crustal dust in the 2013 IPCC report. The high frequency, severity and year-round activity of volcanic dust emissions suggest that Icelandic dust may contribute to Arctic warming.

  2. Four decades of wetland changes of the largest freshwater lake in China in response to the Three Gorges Dam

    Science.gov (United States)

    Feng, L.

    2017-12-01

    Wetlands provide important ecosystem functions for water alteration and conservation of bio-diversity, yet they are vulnerable to both human activities and climate changes. Using four decades of Landsat, MODIS and HJ-1A/1B satellites observations, the long-term wetland changes in Poyang Lake, the largest freshwater lake of China, have been investigated in this study. A Support Vector Machines (SVM) method was firstly developed to obtain wetland classification maps of major cover types between 1973 and 2013 using Landsat and HJ-1A/1B images. A statistically significant increasing trend of the wetland vegetation (15.9 km2 year-1) was found, where the vegetation tended to spread into the lake center in the past four decades. While the transitions from mudflat to vegetation and vice versa were comparable before 2001, vegetation area increased by 620.8 km2 (16.6% of the lake area) between 2001 and 2013. Then, a phenology-based decision tree approach was developed to classify wetland vegetation at community level, with the help of the spatial and spectral information of frequent MODIS observations between 2000 and 2014. MODIS wetland maps confirmed the replacement of water and mudflat by expanded vegetated areas since the impoundment of the Three Gorges Dam (TGD), where both the total coverage of vegetation and the area of each community showed significantly increasing trends. More importantly, results indicated that the vegetation community transitions occurred mainly from hydrophilic cover types to those adapted to dryer conditions. Hydrological analysis revealed that 1) the relationships between the water levels and vegetation coverage showed two regimes for the pre-TGD period (before 2003) and post-TGD period (after 2003); and 2) despite the significant changes in wetland cover types, the most preferable water depth for each cover type remained stable before and after the TGD. The findings here unambiguously led to the conclusion that the landscape changes seen in

  3. STAR Formation Histories Across the Interacting Galaxy NGC 6872, the Largest-Known Spiral

    Science.gov (United States)

    Eufrasio, Rafael T.; Dwek, E.; Arendt, RIchard G.; deMello, Duilia F.; Gadotti, DImitri A.; Urrutia-Viscarra, Fernanda; deOliveira, CLaudia Mendes; Benford, Dominic J.

    2014-01-01

    NGC6872, hereafter the Condor, is a large spiral galaxy that is interacting with its closest companion, the S0 galaxy IC 4970. The extent of the Condor provides an opportunity for detailed investigation of the impact of the interaction on the current star formation rate and its history across the galaxy, on the age and spatial distribution of its stellar population, and on the mechanism that drives the star formation activity. To address these issues we analyzed the far-ultraviolet (FUV) to near-infrared (near-IR) spectral energy distribution of seventeen 10 kpc diameter regions across the galaxy, and derived their star formation history, current star formation rate, and stellar population and mass. We find that most of the star formation takes place in the extended arms, with very little star formation in the central 5 kpc of the galaxy, in contrast to what was predicted from previous numerical simulations. There is a trend of increasing star formation activity with distance from the nucleus of the galaxy, and no evidence for a recent increase in the current star formation rate due to the interaction. The nucleus itself shows no significant current star formation activity. The extent of the Condor also provides an opportunity to test the applicability of a single standard prescription for conversion of the FUV + IR (22 micrometer) intensities to a star formation rate for all regions. We find that the conversion factor differs from region to region, arising from regional differences in the stellar populations.

  4. Health Insurance Premium Increases for the 5 Largest School Districts in the United States, 2004–2008

    Science.gov (United States)

    Cantillo, John R.

    2010-01-01

    Background Local school districts are often one of the largest, if not the largest, employers in their respective communities. Like many large employers, school districts offer health insurance to their employees. There is a lack of information about the rate of health insurance premiums in US school districts relative to other employers. Objective To assess the change in the costs of healthcare insurance in the 5 largest public school districts in the United States, between 2004 and 2008, as representative of large public employers in the country. Methods Data for this study were drawn exclusively from a survey sent to the 5 largest public school districts in the United States. The survey requested responses on 3 data elements for each benefit plan offered from 2004 through 2008; these included enrollment, employee costs, and employer costs. Results The premium growth for the 5 largest school districts has slowed down and is consistent with other purchasers—Kaiser/Health Research & Educational Trust and the Federal Employee Health Benefit Program. The average increase in health insurance premium for the schools was 5.9% in 2008, and the average annual growth rate over the study period was 7.5%. For family coverage, these schools provide the most generous employer contribution (80.8%) compared with the employer contribution reported by other employers (73.5%) for 2008. Conclusions Often the largest employers in their communities, school districts demonstrate a commitment to provide choice of benefits and affordability for employees and their families. Despite constraints typical of public employers, the 5 largest school districts in the United States have decelerated in premium growth consistent with other purchasers, albeit at a slower pace. PMID:25126311

  5. Health insurance premium increases for the 5 largest school districts in the United States, 2004-2008.

    Science.gov (United States)

    Cantillo, John R

    2010-03-01

    Local school districts are often one of the largest, if not the largest, employers in their respective communities. Like many large employers, school districts offer health insurance to their employees. There is a lack of information about the rate of health insurance premiums in US school districts relative to other employers. To assess the change in the costs of healthcare insurance in the 5 largest public school districts in the United States, between 2004 and 2008, as representative of large public employers in the country. Data for this study were drawn exclusively from a survey sent to the 5 largest public school districts in the United States. The survey requested responses on 3 data elements for each benefit plan offered from 2004 through 2008; these included enrollment, employee costs, and employer costs. The premium growth for the 5 largest school districts has slowed down and is consistent with other purchasers-Kaiser/Health Research & Educational Trust and the Federal Employee Health Benefit Program. The average increase in health insurance premium for the schools was 5.9% in 2008, and the average annual growth rate over the study period was 7.5%. For family coverage, these schools provide the most generous employer contribution (80.8%) compared with the employer contribution reported by other employers (73.5%) for 2008. Often the largest employers in their communities, school districts demonstrate a commitment to provide choice of benefits and affordability for employees and their families. Despite constraints typical of public employers, the 5 largest school districts in the United States have decelerated in premium growth consistent with other purchasers, albeit at a slower pace.

  6. Genome of Phaeocystis globosa virus PgV-16T highlights the common ancestry of the largest known DNA viruses infecting eukaryotes

    Science.gov (United States)

    Santini, Sebastien; Jeudy, Sandra; Bartoli, Julia; Poirot, Olivier; Lescot, Magali; Abergel, Chantal; Barbe, Valérie; Wommack, K. Eric; Noordeloos, Anna A. M.; Brussaard, Corina P. D.; Claverie, Jean-Michel

    2013-01-01

    Large dsDNA viruses are involved in the population control of many globally distributed species of eukaryotic phytoplankton and have a prominent role in bloom termination. The genus Phaeocystis (Haptophyta, Prymnesiophyceae) includes several high-biomass-forming phytoplankton species, such as Phaeocystis globosa, the blooms of which occur mostly in the coastal zone of the North Atlantic and the North Sea. Here, we report the 459,984-bp-long genome sequence of P. globosa virus strain PgV-16T, encoding 434 proteins and eight tRNAs and, thus, the largest fully sequenced genome to date among viruses infecting algae. Surprisingly, PgV-16T exhibits no phylogenetic affinity with other viruses infecting microalgae (e.g., phycodnaviruses), including those infecting Emiliania huxleyi, another ubiquitous bloom-forming haptophyte. Rather, PgV-16T belongs to an emerging clade (the Megaviridae) clustering the viruses endowed with the largest known genomes, including Megavirus, Mimivirus (both infecting acanthamoeba), and a virus infecting the marine microflagellate grazer Cafeteria roenbergensis. Seventy-five percent of the best matches of PgV-16T–predicted proteins correspond to two viruses [Organic Lake phycodnavirus (OLPV)1 and OLPV2] from a hypersaline lake in Antarctica (Organic Lake), the hosts of which are unknown. As for OLPVs and other Megaviridae, the PgV-16T sequence data revealed the presence of a virophage-like genome. However, no virophage particle was detected in infected P. globosa cultures. The presence of many genes found only in Megaviridae in its genome and the presence of an associated virophage strongly suggest that PgV-16T shares a common ancestry with the largest known dsDNA viruses, the host range of which already encompasses the earliest diverging branches of domain Eukarya. PMID:23754393

  7. ACTIONS OF THE ADMINISTRATION OF THE FEDERAL SERVICE FOR SURVEILLANCE ON CONSUMER RIGHTS PROTECTION AND HUMANWELL-BEING IN KAMCHATSKY KRAI AND FEDERAL HEALTH ORGANIZATION"CENTER OF HYGIENE AND EPIDEMIOLOGYIN THE KAMCHATSKY KRAI" FOR RADIATION PROTECTION OF THE POPULATION IN CONNECTION WITH THE FUKUSHIMA ACCIDENT

    Directory of Open Access Journals (Sweden)

    N. I. Zhdanova

    2011-01-01

    Full Text Available The article describes actions of the Administration of the Federal Service for Surveillance on Consumer Rights Protection and Human Well-being in KamchatskyKrai and the Federal Health Organization "Center of Hygiene and Epidemiology in the Kamchatsky Krai" to ensure radiation protection of the population in conditions of the radiation accident at Fukushima nuclear power plant and their co-operation with other regional administrations in solution of this problem. The article also presents results of radiation monitoring in the region and shows absence of any significant radiation exposure to the population of the region resulting from the Fukushima nuclear power plant accident.

  8. What caused the UK's largest common dolphin (Delphinus delphis mass stranding event?

    Directory of Open Access Journals (Sweden)

    Paul D Jepson

    Full Text Available On 9 June 2008, the UK's largest mass stranding event (MSE of short-beaked common dolphins (Delphinus delphis occurred in Falmouth Bay, Cornwall. At least 26 dolphins died, and a similar number was refloated/herded back to sea. On necropsy, all dolphins were in good nutritive status with empty stomachs and no evidence of known infectious disease or acute physical injury. Auditory tissues were grossly normal (26/26 but had microscopic haemorrhages (5/5 and mild otitis media (1/5 in the freshest cases. Five lactating adult dolphins, one immature male, and one immature female tested were free of harmful algal toxins and had low chemical pollutant levels. Pathological evidence of mud/seawater inhalation (11/26, local tide cycle, and the relative lack of renal myoglobinuria (26/26 suggested MSE onset on a rising tide between 06:30 and 08∶21 hrs (9 June. Potential causes excluded or considered highly unlikely included infectious disease, gas/fat embolism, boat strike, by-catch, predator attack, foraging unusually close to shore, chemical or algal toxin exposure, abnormal weather/climatic conditions, and high-intensity acoustic inputs from seismic airgun arrays or natural sources (e.g., earthquakes. International naval exercises did occur in close proximity to the MSE with the most intense part of the exercises (including mid-frequency sonars occurring four days before the MSE and resuming with helicopter exercises on the morning of the MSE. The MSE may therefore have been a "two-stage process" where a group of normally pelagic dolphins entered Falmouth Bay and, after 3-4 days in/around the Bay, a second acoustic/disturbance event occurred causing them to strand en masse. This spatial and temporal association with the MSE, previous associations between naval activities and cetacean MSEs, and an absence of other identifiable factors known to cause cetacean MSEs, indicates naval activity to be the most probable cause of the Falmouth Bay MSE.

  9. Transcriptome Sequencing and Analysis for Culm Elongation of the World's Largest Bamboo (Dendrocalamus sinicus.

    Directory of Open Access Journals (Sweden)

    Kai Cui

    Full Text Available Dendrocalamus sinicus is the world's largest bamboo species with strong woody culms, and known for its fast-growing culms. As an economic bamboo species, it was popularized for multi-functional applications including furniture, construction, and industrial paper pulp. To comprehensively elucidate the molecular processes involved in its culm elongation, Illumina paired-end sequencing was conducted. About 65.08 million high-quality reads were produced, and assembled into 81,744 unigenes with an average length of 723 bp. A total of 64,338 (79% unigenes were annotated for their functions, of which, 56,587 were annotated in the NCBI non-redundant protein database and 35,262 were annotated in the Swiss-Prot database. Also, 42,508 and 21,009 annotated unigenes were allocated to gene ontology (GO categories and clusters of orthologous groups (COG, respectively. By searching against the Kyoto Encyclopedia of Genes and Genomes Pathway database (KEGG, 33,920 unigenes were assigned to 128 KEGG pathways. Meanwhile, 8,553 simple sequence repeats (SSRs and 81,534 single-nucleotide polymorphism (SNPs were identified, respectively. Additionally, 388 transcripts encoding lignin biosynthesis were detected, among which, 27 transcripts encoding Shikimate O-hydroxycinnamoyltransferase (HCT specifically expressed in D. sinicus when compared to other bamboo species and rice. The phylogenetic relationship between D. sinicus and other plants was analyzed, suggesting functional diversity of HCT unigenes in D. sinicus. We conjectured that HCT might lead to the high lignin content and giant culm. Given that the leaves are not yet formed and culm is covered with sheaths during culm elongation, the existence of photosynthesis of bamboo culm is usually neglected. Surprisedly, 109 transcripts encoding photosynthesis were identified, including photosystem I and II, cytochrome b6/f complex, photosynthetic electron transport and F-type ATPase, and 24 transcripts were characterized

  10. Evaluation of world's largest social welfare scheme: An assessment using non-parametric approach.

    Science.gov (United States)

    Singh, Sanjeet

    2016-08-01

    Mahatma Gandhi National Rural Employment Guarantee Act (MGNREGA) is the world's largest social welfare scheme in India for the poverty alleviation through rural employment generation. This paper aims to evaluate and rank the performance of the states in India under MGNREGA scheme. A non-parametric approach, Data Envelopment Analysis (DEA) is used to calculate the overall technical, pure technical, and scale efficiencies of states in India. The sample data is drawn from the annual official reports published by the Ministry of Rural Development, Government of India. Based on three selected input parameters (expenditure indicators) and five output parameters (employment generation indicators), I apply both input and output oriented DEA models to estimate how well the states utilize their resources and generate outputs during the financial year 2013-14. The relative performance evaluation has been made under the assumption of constant returns and also under variable returns to scale to assess the impact of scale on performance. The results indicate that the main source of inefficiency is both technical and managerial practices adopted. 11 states are overall technically efficient and operate at the optimum scale whereas 18 states are pure technical or managerially efficient. It has been found that for some states it necessary to alter scheme size to perform at par with the best performing states. For inefficient states optimal input and output targets along with the resource savings and output gains are calculated. Analysis shows that if all inefficient states operate at optimal input and output levels, on an average 17.89% of total expenditure and a total amount of $780million could have been saved in a single year. Most of the inefficient states perform poorly when it comes to the participation of women and disadvantaged sections (SC&ST) in the scheme. In order to catch up with the performance of best performing states, inefficient states on an average need to enhance

  11. Africa's largest long-lasting insecticide-treated net producer: lessons from A to Z Textiles.

    Science.gov (United States)

    Masum, Hassan; Shah, Ronak; Schroeder, Karl; Daar, Abdallah S; Singer, Peter A

    2010-12-13

    Field trials have demonstrated the efficacy of insecticide-treated nets, and the WHO has recently endorsed a shift toward Long-Lasting Insecticide Treated nets (LLINs) due to factors such as reduced distribution costs. However, the need for LLINs poses several challenges. Is it possible to manufacture LLINs in large quantities in the African continent, where malaria is most endemic? When production is located in low-income countries, what role is played by local funding and employment, scaling up manufacturing, and partnerships? What factors influence availability and pricing? A case study of A to Z Textiles was undertaken to answer the question of how large-scale production of LLINs can occur in a low income setting. One of the largest sources of bed nets for Africa, A to Z Textiles is Africa-based, and its Tanzanian operations have a production capacity of 30 million LLINs per year, along with full WHO recommendation for its nets. Our analysis is based on semi-structured interviews with key informants familiar with A to Z, site visits in Tanzania, and literature reviews.This paper discusses the history and current status of A to Z Textiles, identifies the factors that led to its success, and suggests policy considerations that could support similar initiatives in the future. Local funding, scaling up manufacturing, technology transfer, and partnerships all played important roles in A to Z's ascent, as did perceived benefits of local employment and capacity-building. Regulatory issues and procurement rules acted as barriers. A to Z cost-effectively manufactures high-quality LLINs where malaria is most endemic. With a production capacity of 30 million LLINs per year, and full WHOPES (WHO Pesticide Evaluation Scheme) certification, A to Z Textiles demonstrates how key health goods can be successfully produced in the low-income countries that use them. Its example may be instructive and of high interest to readers in the malaria community, especially in developing

  12. Helicobacter pylori virulence genes in the five largest islands of Indonesia.

    Science.gov (United States)

    Miftahussurur, Muhammad; Syam, Ari Fahrial; Makmun, Dadang; Nusi, Iswan Abbas; Zein, Lukman Hakim; Zulkhairi; Akil, Fardah; Uswan, Willi Brodus; Simanjuntak, David; Uchida, Tomohisa; Adi, Pangestu; Utari, Amanda Pitarini; Rezkitha, Yudith Annisa Ayu; Subsomwong, Phawinee; Nasronudin; Yamaoka, Yoshio

    2015-01-01

    It remains unclear whether the low incidence of gastric cancer in Indonesia is due to low infection rates only or is also related to low Helicobacter pylori pathogenicity. We collected H. pylori strains from the five largest islands in Indonesia and evaluated genetic virulence factors. The genotypes of H. pylori virulence factors were determined by polymerase chain reaction (PCR)-based sequencing. Histological severity of the gastric mucosa was classified into 4 grades, according to the updated Sydney system. A total of 44 strains were analyzed. Forty-three (97.7 %) were cagA-positive: 26 (60.5 %) were East-Asian-type-cagA, 9 (20.9 %) were Western-type-cagA, and 8 (18.6 %) were novel ABB-type, most of which were obtained from Papuan. EPIYT sequences were more prevalent than EPIYA sequences (P = 0.01) in the EPIYA-B motif of all types of cagA. The majority of cagA-positive strains (48.8 %, 21/43) had a 6-bp deletion in the first pre-EPIYA region. Subjects infected with East-Asian-type-cagA strains with a 6-bp deletion had significantly lower inflammation and atrophy scores in the corpus than those infected with Western-type-cagA strains (both P = 0.02). In total, 70.4 % of strains possessed the vacA s1m1 genotype and 29.5 % were m2. All strains from peptic ulcer patients were of the iceA1 genotype, which occurred at a significantly higher proportion in peptic ulcer patients than that in gastritis patients (55.3 %, P = 0.04). The double positive genotype of jhp0562/β-(1,3)galT was predominant (28/44, 63.6 %), and subjects infected with this type had significantly higher inflammation scores in the corpus than those with the jhp0562 negative/β-(1,3)galT positive genotype (mean [median]; 1.43 [1] vs. 0.83 [1], P = 0.04). There were significant differences in cagA and pre-EPIYA cagA type, oipA status, and jhp0562/β-(1,3)galT type among different ethnic groups (P dupA negative or short type dupA, and the jhp0562/β-(1,3)galT double positive genotype.

  13. What Caused the UK's Largest Common Dolphin (Delphinus delphis) Mass Stranding Event?

    Science.gov (United States)

    Jepson, Paul D.; Deaville, Robert; Acevedo-Whitehouse, Karina; Barnett, James; Brownlow, Andrew; Brownell Jr., Robert L.; Clare, Frances C.; Davison, Nick; Law, Robin J.; Loveridge, Jan; Macgregor, Shaheed K.; Morris, Steven; Murphy, Sinéad; Penrose, Rod; Perkins, Matthew W.; Pinn, Eunice; Seibel, Henrike; Siebert, Ursula; Sierra, Eva; Simpson, Victor; Tasker, Mark L.; Tregenza, Nick; Cunningham, Andrew A.; Fernández, Antonio

    2013-01-01

    On 9 June 2008, the UK's largest mass stranding event (MSE) of short-beaked common dolphins (Delphinus delphis) occurred in Falmouth Bay, Cornwall. At least 26 dolphins died, and a similar number was refloated/herded back to sea. On necropsy, all dolphins were in good nutritive status with empty stomachs and no evidence of known infectious disease or acute physical injury. Auditory tissues were grossly normal (26/26) but had microscopic haemorrhages (5/5) and mild otitis media (1/5) in the freshest cases. Five lactating adult dolphins, one immature male, and one immature female tested were free of harmful algal toxins and had low chemical pollutant levels. Pathological evidence of mud/seawater inhalation (11/26), local tide cycle, and the relative lack of renal myoglobinuria (26/26) suggested MSE onset on a rising tide between 06∶30 and 08∶21 hrs (9 June). Potential causes excluded or considered highly unlikely included infectious disease, gas/fat embolism, boat strike, by-catch, predator attack, foraging unusually close to shore, chemical or algal toxin exposure, abnormal weather/climatic conditions, and high-intensity acoustic inputs from seismic airgun arrays or natural sources (e.g., earthquakes). International naval exercises did occur in close proximity to the MSE with the most intense part of the exercises (including mid-frequency sonars) occurring four days before the MSE and resuming with helicopter exercises on the morning of the MSE. The MSE may therefore have been a “two-stage process” where a group of normally pelagic dolphins entered Falmouth Bay and, after 3–4 days in/around the Bay, a second acoustic/disturbance event occurred causing them to strand en masse. This spatial and temporal association with the MSE, previous associations between naval activities and cetacean MSEs, and an absence of other identifiable factors known to cause cetacean MSEs, indicates naval activity to be the most probable cause of the Falmouth Bay MSE. PMID

  14. Transcriptome Sequencing and Analysis for Culm Elongation of the World's Largest Bamboo (Dendrocalamus sinicus).

    Science.gov (United States)

    Cui, Kai; Wang, Haiying; Liao, Shengxi; Tang, Qi; Li, Li; Cui, Yongzhong; He, Yuan

    2016-01-01

    Dendrocalamus sinicus is the world's largest bamboo species with strong woody culms, and known for its fast-growing culms. As an economic bamboo species, it was popularized for multi-functional applications including furniture, construction, and industrial paper pulp. To comprehensively elucidate the molecular processes involved in its culm elongation, Illumina paired-end sequencing was conducted. About 65.08 million high-quality reads were produced, and assembled into 81,744 unigenes with an average length of 723 bp. A total of 64,338 (79%) unigenes were annotated for their functions, of which, 56,587 were annotated in the NCBI non-redundant protein database and 35,262 were annotated in the Swiss-Prot database. Also, 42,508 and 21,009 annotated unigenes were allocated to gene ontology (GO) categories and clusters of orthologous groups (COG), respectively. By searching against the Kyoto Encyclopedia of Genes and Genomes Pathway database (KEGG), 33,920 unigenes were assigned to 128 KEGG pathways. Meanwhile, 8,553 simple sequence repeats (SSRs) and 81,534 single-nucleotide polymorphism (SNPs) were identified, respectively. Additionally, 388 transcripts encoding lignin biosynthesis were detected, among which, 27 transcripts encoding Shikimate O-hydroxycinnamoyltransferase (HCT) specifically expressed in D. sinicus when compared to other bamboo species and rice. The phylogenetic relationship between D. sinicus and other plants was analyzed, suggesting functional diversity of HCT unigenes in D. sinicus. We conjectured that HCT might lead to the high lignin content and giant culm. Given that the leaves are not yet formed and culm is covered with sheaths during culm elongation, the existence of photosynthesis of bamboo culm is usually neglected. Surprisedly, 109 transcripts encoding photosynthesis were identified, including photosystem I and II, cytochrome b6/f complex, photosynthetic electron transport and F-type ATPase, and 24 transcripts were characterized as antenna

  15. Africa's largest long-lasting insecticide-treated net producer: lessons from A to Z Textiles

    Directory of Open Access Journals (Sweden)

    Daar Abdallah S

    2010-12-01

    Full Text Available Abstract Background Field trials have demonstrated the efficacy of insecticide-treated nets, and the WHO has recently endorsed a shift toward Long-Lasting Insecticide Treated nets (LLINs due to factors such as reduced distribution costs. However, the need for LLINs poses several challenges. Is it possible to manufacture LLINs in large quantities in the African continent, where malaria is most endemic? When production is located in low-income countries, what role is played by local funding and employment, scaling up manufacturing, and partnerships? What factors influence availability and pricing? Discussion A case study of A to Z Textiles was undertaken to answer the question of how large-scale production of LLINs can occur in a low income setting. One of the largest sources of bed nets for Africa, A to Z Textiles is Africa-based, and its Tanzanian operations have a production capacity of 30 million LLINs per year, along with full WHO recommendation for its nets. Our analysis is based on semi-structured interviews with key informants familiar with A to Z, site visits in Tanzania, and literature reviews. This paper discusses the history and current status of A to Z Textiles, identifies the factors that led to its success, and suggests policy considerations that could support similar initiatives in the future. Local funding, scaling up manufacturing, technology transfer, and partnerships all played important roles in A to Z’s ascent, as did perceived benefits of local employment and capacity-building. Regulatory issues and procurement rules acted as barriers. A to Z cost-effectively manufactures high-quality LLINs where malaria is most endemic. Summary With a production capacity of 30 million LLINs per year, and full WHOPES (WHO Pesticide Evaluation Scheme certification, A to Z Textiles demonstrates how key health goods can be successfully produced in the low-income countries that use them. Its example may be instructive and of high interest to

  16. Terrorist attacks in the largest metropolitan city of Pakistan: Profile of soft tissue and skeletal injuries from a single trauma center.

    Science.gov (United States)

    Khan, Muhammad Shahid; Waheed, Shahan; Ali, Arif; Mumtaz, Narjis; Feroze, Asher; Noordin, Shahryar

    2015-01-01

    Pakistan has been hugely struck with massive bomb explosions (car and suicide bombs) resulting in multiple casualties in the past few years. The aim of this study is to present the patterns of skeletal and soft tissue injuries and to review the outcome of the victims who presented to our hospital. This is a retrospective chart review from January 2008 to December 2012. The medical record numbers of patients were obtained from the hospital Health Information and Management Sciences (HIMS) as per the ICD-9 coding. During the study period, more than 100 suicide and implanted bomb blast attacks took place in the public proceedings, government offices, residential areas and other places of the city. Altogether 262 patients were enrolled in the study. The mean age of the patients was 31±14 years. The shrapnel inflicted wounds were present on to the upper limb in 24 patients and the lower limb in 50. Long bone fractures were the most common skeletal injuries. The fractures were complicated by penetrating fragments and nails which result in post operative infections and prolonged hospital stay.

  17. Recent progress in simulating galaxy formation from the largest to the smallest scales

    Science.gov (United States)

    Faucher-Giguère, Claude-André

    2018-05-01

    Galaxy formation simulations are an essential part of the modern toolkit of astrophysicists and cosmologists alike. Astrophysicists use the simulations to study the emergence of galaxy populations from the Big Bang, as well as the formation of stars and supermassive black holes. For cosmologists, galaxy formation simulations are needed to understand how baryonic processes affect measurements of dark matter and dark energy. Owing to the extreme dynamic range of galaxy formation, advances are driven by novel approaches using simulations with different tradeoffs between volume and resolution. Large-volume but low-resolution simulations provide the best statistics, while higher-resolution simulations of smaller cosmic volumes can be evolved with self-consistent physics and reveal important emergent phenomena. I summarize recent progress in galaxy formation simulations, including major developments in the past five years, and highlight some key areas likely to drive further advances over the next decade.

  18. Human Skin Is the Largest Epithelial Surface for Interaction with Microbes.

    Science.gov (United States)

    Gallo, Richard L

    2017-06-01

    Human skin contains an abundant and diverse population of microbial organisms. Many of these microbes inhabit follicular structures of the skin. Furthermore, numerous studies have shown that the interaction of some members of the skin microbiome with host cells will result in changes in cell function. However, estimates of the potential for the microbiome to influence human health through skin have ignored the inner follicular surface, and therefore vastly underestimated the potential of the skin microbiome to have a systemic effect on the human body. By calculating the surface area of follicular and the interfollicular epithelial surface it is shown that skin provides a vast interface for interactions with the microbiome. Copyright © 2017 The Author. Published by Elsevier Inc. All rights reserved.

  19. The Red MSX Source Survey: The Massive Young Stellar Population of Our Galaxy

    Science.gov (United States)

    Lumsden, S. L.; Hoare, M. G.; Urquhart, J. S.; Oudmaijer, R. D.; Davies, B.; Mottram, J. C.; Cooper, H. D. B.; Moore, T. J. T.

    2013-09-01

    We present the Red MSX Source survey, the largest statistically selected catalog of young massive protostars and H II regions to date. We outline the construction of the catalog using mid- and near-infrared color selection. We also discuss the detailed follow up work at other wavelengths, including higher spatial resolution data in the infrared. We show that within the adopted selection bounds we are more than 90% complete for the massive protostellar population, with a positional accuracy of the exciting source of better than 2 arcsec. We briefly summarize some of the results that can be obtained from studying the properties of the objects in the catalog as a whole; we find evidence that the most massive stars form: (1) preferentially nearer the Galactic center than the anti-center; (2) in the most heavily reddened environments, suggestive of high accretion rates; and (3) from the most massive cloud cores.

  20. THE RED MSX SOURCE SURVEY: THE MASSIVE YOUNG STELLAR POPULATION OF OUR GALAXY

    International Nuclear Information System (INIS)

    Lumsden, S. L.; Hoare, M. G.; Oudmaijer, R. D.; Cooper, H. D. B.; Urquhart, J. S.; Davies, B.; Moore, T. J. T.; Mottram, J. C.

    2013-01-01

    We present the Red MSX Source survey, the largest statistically selected catalog of young massive protostars and H II regions to date. We outline the construction of the catalog using mid- and near-infrared color selection. We also discuss the detailed follow up work at other wavelengths, including higher spatial resolution data in the infrared. We show that within the adopted selection bounds we are more than 90% complete for the massive protostellar population, with a positional accuracy of the exciting source of better than 2 arcsec. We briefly summarize some of the results that can be obtained from studying the properties of the objects in the catalog as a whole; we find evidence that the most massive stars form: (1) preferentially nearer the Galactic center than the anti-center; (2) in the most heavily reddened environments, suggestive of high accretion rates; and (3) from the most massive cloud cores

  1. THE RED MSX SOURCE SURVEY: THE MASSIVE YOUNG STELLAR POPULATION OF OUR GALAXY

    Energy Technology Data Exchange (ETDEWEB)

    Lumsden, S. L.; Hoare, M. G.; Oudmaijer, R. D.; Cooper, H. D. B. [School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT (United Kingdom); Urquhart, J. S. [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, Bonn (Germany); Davies, B.; Moore, T. J. T. [Astrophysics Research Institute, Liverpool John Moores University, Liverpool L3 5RF (United Kingdom); Mottram, J. C. [Leiden Observatory, Leiden University, P.O. Box 9513, 2300 RA Leiden (Netherlands)

    2013-09-01

    We present the Red MSX Source survey, the largest statistically selected catalog of young massive protostars and H II regions to date. We outline the construction of the catalog using mid- and near-infrared color selection. We also discuss the detailed follow up work at other wavelengths, including higher spatial resolution data in the infrared. We show that within the adopted selection bounds we are more than 90% complete for the massive protostellar population, with a positional accuracy of the exciting source of better than 2 arcsec. We briefly summarize some of the results that can be obtained from studying the properties of the objects in the catalog as a whole; we find evidence that the most massive stars form: (1) preferentially nearer the Galactic center than the anti-center; (2) in the most heavily reddened environments, suggestive of high accretion rates; and (3) from the most massive cloud cores.

  2. Banking Umbilical Cord Blood (UCB) Stem Cells: Awareness, Attitude and Expectations of Potential Donors from One of the Largest Potential Repository (India).

    Science.gov (United States)

    Pandey, Deeksha; Kaur, Simar; Kamath, Asha

    2016-01-01

    The concept of Umbilical Cord blood (UCB) stem cells is emerging as a non-invasive, efficacious alternative source of hematopoietic stem cells to treat a variety of blood and bone marrow diseases, blood cancers, metabolic disorders and immune deficiencies. Aim of the present study was to determine the level of awareness about banking UCB among pregnant women in India. We also assessed patient perception for banking of UCB and explored the patient expectations of banking UCB in future. This is the first study to assess current attitudes, in a sample population of potential donors from one of the largest potential UCB repository (India). Obtaining this information may help optimize recruitment efforts and improve patient education. Present explorative questionnaire based survey included 254 pregnant women in the final analysis. We established only 26.5% pregnant women in our study population knew what exactly is meant by UCB. A large proportion (55.1%) was undecided on whether they want to bank UCB or not. Women were more aware of the more advertised private cord blood banking compared to public banking. More than half of the pregnant women expected their obstetrician to inform them regarding UCB. One-third of the women in our population had undue expectations from banking of the UCB. Obstetricians should play a more active role in explaining the patients regarding pros and cons of UCB banking.

  3. Banking Umbilical Cord Blood (UCB Stem Cells: Awareness, Attitude and Expectations of Potential Donors from One of the Largest Potential Repository (India.

    Directory of Open Access Journals (Sweden)

    Deeksha Pandey

    Full Text Available The concept of Umbilical Cord blood (UCB stem cells is emerging as a non-invasive, efficacious alternative source of hematopoietic stem cells to treat a variety of blood and bone marrow diseases, blood cancers, metabolic disorders and immune deficiencies. Aim of the present study was to determine the level of awareness about banking UCB among pregnant women in India. We also assessed patient perception for banking of UCB and explored the patient expectations of banking UCB in future. This is the first study to assess current attitudes, in a sample population of potential donors from one of the largest potential UCB repository (India. Obtaining this information may help optimize recruitment efforts and improve patient education.Present explorative questionnaire based survey included 254 pregnant women in the final analysis.We established only 26.5% pregnant women in our study population knew what exactly is meant by UCB. A large proportion (55.1% was undecided on whether they want to bank UCB or not. Women were more aware of the more advertised private cord blood banking compared to public banking. More than half of the pregnant women expected their obstetrician to inform them regarding UCB. One-third of the women in our population had undue expectations from banking of the UCB.Obstetricians should play a more active role in explaining the patients regarding pros and cons of UCB banking.

  4. The development of online doctor reviews in China: an analysis of the largest online doctor review website in China.

    Science.gov (United States)

    Hao, Haijing

    2015-06-01

    Since the time of Web 2.0, more and more consumers have used online doctor reviews to rate their doctors or to look for a doctor. This phenomenon has received health care researchers' attention worldwide, and many studies have been conducted on online doctor reviews in the United States and Europe. But no study has yet been done in China. Also, in China, without a mature primary care physician recommendation system, more and more Chinese consumers seek online doctor reviews to look for a good doctor for their health care concerns. This study sought to examine the online doctor review practice in China, including addressing the following questions: (1) How many doctors and specialty areas are available for online review? (2) How many online reviews are there on those doctors? (3) What specialty area doctors are more likely to be reviewed or receive more reviews? (4) Are those reviews positive or negative? This study explores an empirical dataset from Good Doctor website, haodf.com—the earliest and largest online doctor review and online health care community website in China—from 2006 to 2014, to examine the stated research questions by using descriptive statistics, binary logistic regression, and multivariate linear regression. The dataset from the Good Doctor website contained 314,624 doctors across China and among them, 112,873 doctors received 731,543 quantitative reviews and 772,979 qualitative reviews as of April 11, 2014. On average, 37% of the doctors had been reviewed on the Good Doctor website. Gynecology-obstetrics-pediatrics doctors were most likely to be reviewed, with an odds ratio (OR) of 1.497 (95% CI 1.461-1.535), and internal medicine doctors were less likely to be reviewed, with an OR of 0.94 (95% CI 0.921-0.960), relative to the combined small specialty areas. Both traditional Chinese medicine doctors and surgeons were more likely to be reviewed than the combined small specialty areas, with an OR of 1.483 (95% CI 1.442-1.525) and an OR of 1

  5. Population and population policy in Pakistan.

    Science.gov (United States)

    Mauldin, W P

    1963-02-01

    Pakistan is a divided country with different religious groups represented. Since independence in 1941, the Muslim population has increased more rapidly than the Hindu population, the West Pakistan population more rapidly and steadily than the East Pakistan population. In the late 1950s the Pakistan government initiated a family planning program. The program has trained medical and paramedical personnel in family planning, added family planning services to existing medical centers, planned for a National Research Institute of Family Planning, employed mobile units to reach outlying areas, conducted limited clinical studies on some contraceptives, and used mass media advertising. Only India and Japan are doing more with government-sponsored family planning. A weak organizational structure and an inadequate number of trained personnel are the main weakness of the program. It is too early to assess the success of the program. A 10-point reduction in annual birth rates will be considered successful.

  6. Sources and characteristics of carbonaceous aerosol in two largest cities in Pearl River Delta Region, China

    Science.gov (United States)

    Duan, Jingchun; Tan, Jihua; Cheng, Dingxi; Bi, Xinhui; Deng, Wenjing; Sheng, Guoying; Fu, Jiamo; Wong, M. H.

    PM 2.5 samples were collected at five sites in Guangzhou and Hong Kong, Pearl River Delta Region (PRDR), China in both summer and winter during 2004-2005. Elemental carbon (EC) and organic carbon (OC) in these samples were measured. The OC and EC concentrations ranked in the order of urban Guangzhou > urban Hong Kong > background Hong Kong. Total carbonaceous aerosol (TCA) contributed less to PM 2.5 in urban Guangzhou (32-35%) than that in urban Hong Kong (43-57%). The reason may be that, as an major industrial city in South China, Guangzhou would receive large amount of inorganic aerosol from all kinds of industries, however, as a trade center and seaport, urban Hong Kong would mainly receive organic aerosol and EC from container vessels and heavy-duty diesel trucks. At Hong Kong background site Hok Tsui, relatively lower contribution of TCA to PM 2.5 may result from contributions of marine inorganic aerosol and inland China pollutant. Strong correlation ( R2=0.76-0.83) between OC and EC indicates minor fluctuation of emission and the secondary organic aerosol (SOA) formation in urban Guangzhou. Weak correlation between OC and EC in Hong Kong can be related to the impact of the long-range transported aerosol from inland China. Averagely, secondary OC (SOC) concentrations were 3.8-5.9 and 10.2-12.8 μg m -3, respectively, accounting for 21-32% and 36-42% of OC in summer and winter in Guangzhou. The average values of 4.2-6.8% for SOA/ PM 2.5 indicate that SOA was minor component in PM 2.5 in Guangzhou.

  7. Epidemiological profile of naive HIV-1/AIDS patients in Istanbul: the largest case series from Turkey.

    Science.gov (United States)

    Yemisen, Mucahit; Aydın, Ozlem Altuntas; Gunduz, Alper; Ozgunes, Nail; Mete, Bilgul; Ceylan, Bahadir; Karaosmanoglu, Hayat Kumbasar; Yildiz, Dilek; Sargin, Fatma; Ozaras, Resat; Tabak, Fehmi

    2014-01-01

    The aim of the study was to report the epidemiological profile of HIV-1 positive patients from, Istanbul, Turkey, which has one of the lowest HIV-1/AIDS prevalences in Europe. The patients were followed by ACTHIV-IST group which was established by the Infectious Diseases Departments of five teaching hospitals (three university hospitals and two public hospitals) in Istanbul, Turkey. The HIV-1 positive patients were added to the standard patient files in all of the centers; these files were then transferred to the ACTHIV-IST database in the Internet. A total of 829 naiv-untreated HIV-1 positive patients were chosen from the database. The number of male patients was 700 (84.4%) and the mean age of the patients was 37 years (range, 17-79). In our study group 348 (42%) of the patients were married and 318 (38.7%) of the patients were single. The probable route of transmission was heterosexual intercourse in 437 (52.7%) patients and homosexual intercourse in 256 (30.9%) patients. In 519 (62.6%) patients the diagnose was made due to a screening test and in 241 (29.1%) patients, the diagnose was made due to an HIV-related/non-related disease. The mean CD4+ T cell number in 788 of the patients was 357.8/mm(3) (±271.1), and the median viral load in 698 of the patients was 100,000 copies/mL (20-9,790,000). In Turkey, the number of HIV-1 positive patients is still low and to diagnose with a screening test is the most common way of diagnostic route.

  8. ESO Signs Largest-Ever European Industrial Contract For Ground-Based Astronomy Project ALMA

    Science.gov (United States)

    2005-12-01

    ESO, the European Organisation for Astronomical Research in the Southern Hemisphere, announced today that it has signed a contract with the consortium led by Alcatel Alenia Space and composed also of European Industrial Engineering (Italy) and MT Aerospace (Germany), to supply 25 antennas for the Atacama Large Millimeter Array (ALMA) project, along with an option for another seven antennas. The contract, worth 147 million euros, covers the design, manufacture, transport and on-site integration of the antennas. It is the largest contract ever signed in ground-based astronomy in Europe. The ALMA antennas present difficult technical challenges, since the antenna surface accuracy must be within 25 microns, the pointing accuracy within 0.6 arc seconds, and the antennas must be able to be moved between various stations on the ALMA site. This is especially remarkable since the antennas will be located outdoor in all weather conditions, without any protection. Moreover, the ALMA antennas can be pointed directly at the Sun. ALMA will have a collecting area of more than 5,600 square meters, allowing for unprecedented measurements of extremely faint objects. The signing ceremony took place on December 6, 2005 at ESO Headquarters in Garching, Germany. "This contract represents a major milestone. It allows us to move forward, together with our American and Japanese colleagues, in this very ambitious and unique project," said ESO's Director General, Dr. Catherine Cesarsky. "By building ALMA, we are giving European astronomers access to the world's leading submillimetre facility at the beginning of the next decade, thereby fulfilling Europe's desire to play a major role in this field of fundamental research." Pascale Sourisse, Chairman and CEO of Alcatel Alenia Space, said: "We would like to thank ESO for trusting us to take on this new challenge. We are bringing to the table not only our recognized expertise in antenna development, but also our long-standing experience in

  9. Deep, diverse and definitely different: unique attributes of the world's largest ecosystem

    Directory of Open Access Journals (Sweden)

    E. Ramirez-Llodra

    2010-09-01

    Full Text Available The deep sea, the largest biome on Earth, has a series of characteristics that make this environment both distinct from other marine and land ecosystems and unique for the entire planet. This review describes these patterns and processes, from geological settings to biological processes, biodiversity and biogeographical patterns. It concludes with a brief discussion of current threats from anthropogenic activities to deep-sea habitats and their fauna.

    Investigations of deep-sea habitats and their fauna began in the late 19th century. In the intervening years, technological developments and stimulating discoveries have promoted deep-sea research and changed our way of understanding life on the planet. Nevertheless, the deep sea is still mostly unknown and current discovery rates of both habitats and species remain high. The geological, physical and geochemical settings of the deep-sea floor and the water column form a series of different habitats with unique characteristics that support specific faunal communities. Since 1840, 28 new habitats/ecosystems have been discovered from the shelf break to the deep trenches and discoveries of new habitats are still happening in the early 21st century. However, for most of these habitats the global area covered is unknown or has been only very roughly estimated; an even smaller – indeed, minimal – proportion has actually been sampled and investigated. We currently perceive most of the deep-sea ecosystems as heterotrophic, depending ultimately on the flux on organic matter produced in the overlying surface ocean through photosynthesis. The resulting strong food limitation thus shapes deep-sea biota and communities, with exceptions only in reducing ecosystems such as inter alia hydrothermal vents or cold seeps. Here, chemoautolithotrophic bacteria play the role of primary producers fuelled by chemical energy sources rather than sunlight. Other ecosystems, such as seamounts, canyons or cold

  10. Business Subsidies in Canada Comprehensive Estimates for the Government of Canada and the Four Largest Provinces

    Directory of Open Access Journals (Sweden)

    John Lester

    2018-01-01

    Full Text Available Business subsidies in Canada: the “winner” is Alberta; the loser is the taxpayer The federal government and the four largest provinces in Canada spend about $29 billion a year on business subsidies, delivered through program spending, the tax system, government business enterprises and direct investments by government. These subsidies represent almost half of the corporate income tax revenue collected by the five jurisdictions. Surprisingly, given its reputation as a bastion of free enterprise, Alberta is the most prolific subsidizer. In the 2014-15 fiscal year, per person subsidies were $640 in Alberta, about $100 ahead of the next most generous jurisdiction, Québec. Alberta has probably added to its “lead” through measures introduced in the October 2015 Fiscal Update and the 2016 budget. Alberta also stands out by having the least transparent public reporting of business subsidies. What motivates governments to subsidize business? Abstracting from cynical efforts to win votes, business subsidies have two broad objectives: to improve economic performance and to achieve a social objective by supporting specific firms, industries or regions. On average in the five jurisdictions, the split between the two categories is about 70-30 in favour of economic development measures. Assessing value for money from programs with a social objective is subjective, but measures intended to improve economic performance should be assessed on their ability to raise real income. Business subsidies can only raise real income if markets fail to allocate labour and capital to their best uses. The classic case is R&D. When a firm undertakes R&D, some of the knowledge created inevitably spills over to the benefit other firms. Firms are focused on their own benefits and costs when deciding how much to spend on R&D, not the benefits received by other firms, so society has an interest in encouraging additional R&D. While markets generally do a good job allocating

  11. Plant species and communities in Poyang Lake, the largest freshwater lake in China

    Directory of Open Access Journals (Sweden)

    Wang, H. F.

    2015-12-01

    Full Text Available Studying plant species richness and composition of a wetland is essential when estimating its ecological importance and ecosystem services, especially if a particular wetland is subjected to human disturbances. Poyang Lake, located in the middle reaches of Yangtze River (central China, constitutes the largest freshwater lake of the country. It harbours high biodiversity and provides important habitat for local wildlife. A dam that will maintain the water capacity in Poyang Lake is currently being planned. However, the local biodiversity and the likely effects of this dam on the biodiversity (especially on the endemic and rare plants have not been thoroughly examined. Therefore, in order to assess the richness of plant species and plant communities in Poyang Lake, we conducted a detailed field investigation combined with a literature review. A total of 124 families, 339 genera, and 512 species (including sub-species, varieties and forms as well as eight dominant plant communities were identified, confirming the lake’s wetland as a regional hotspot of plant diversity. It is imperative to carry out further research on the impact of damming on the vegetation, particularly research focusing on protecting local biodiversity, maintaining the lake’s ecosystem services, controlling the spread of invasive species, and restoring degraded ecosystems.El estudio de la riqueza y la composición de especies vegetales de un humedal es esencial a la hora de estimar su importancia ecológica y sus servicios ecosistémicos, especialmente cuando éste está sujeto a perturbaciones humanas. El lago Poyang, situado en el curso medio del río Yangtsé (China central constituye la mayor superfície de agua dulce del país. Alberga una elevada biodiversidad y proporciona hábitats importantes para la flora y fauna locales. En la actualidad existen planes de construir una presa que mantendrá el volumen de agua del lago estable. Sin embargo, y hasta la fecha, apenas

  12. Iowa Water Center | Iowa Water Center

    Science.gov (United States)

    Home Iowa State University Extension Iowa Water Center Submitted by mollyd on April 24, 2012 - 09 :42 Advancing the state of water knowledge and management The Iowa Water Center is a part of a nationwide network of university-based water centers created to encourage interdisciplinary water research

  13. Ownership, financing, and management strategies of the ten largest for-profit nursing home chains in the United States.

    Science.gov (United States)

    Harrington, Charlene; Hauser, Clarilee; Olney, Brian; Rosenau, Pauline Vaillancourt

    2011-01-01

    This study examined the ownership, financing, and management strategies of the 10 largest for-profit nursing home chains in the United States, including the four largest chains purchased by private equity corporations. Descriptive data were collected from Internet searches, company reports, and other sources for the decade 1998-2008. Since 1998, the largest chains have made many changes in their ownership and structure, and some have converted from publicly traded companies to private ownership. This study shows the increasing complexity of corporate nursing home ownership and the lack of public information about ownership and financial status. The chains have used strategies to maximize shareholder and investor value that include increasing Medicare revenues, occupancy rates, and company diversification, establishing multiple layers of corporate ownership, developing real estate investment trusts, and creating limited liability companies. These strategies enhance shareholder and investor profits, reduce corporate taxes, and reduce liability risk. There is a need for greater transparency in ownership and financial reporting and for more government oversight of the largest for-profit chains, including those owned by private equity companies.

  14. Haven't We Been Here Before? Some Comments on Steve Coffman's Proposal for "Earth's Largest Library".

    Science.gov (United States)

    McGervey, Teresa

    2000-01-01

    Discusses the concept of Earth's Largest Library (ELL), a mega-virtual library based on the Amazon.com model. Topics include who will be included; privacy; censorship; scope of the collection; costs; legal aspects; collection development; personnel management; access; the concept of community; public service; lending policies; technical…

  15. Estimate of the largest Lyapunov characteristic exponent of a high dimensional atmospheric global circulation model: a sensitivity analysis

    International Nuclear Information System (INIS)

    Guerrieri, A.

    2009-01-01

    In this report the largest Lyapunov characteristic exponent of a high dimensional atmospheric global circulation model of intermediate complexity has been estimated numerically. A sensitivity analysis has been carried out by varying the equator-to-pole temperature difference, the space resolution and the value of some parameters employed by the model. Chaotic and non-chaotic regimes of circulation have been found. [it

  16. Estimating the recreational value of Pakistan's largest freshwater lake to support sustainable tourism management using a travel cost model

    NARCIS (Netherlands)

    Mangan, T.; Brouwer, R.; Lohano, H.; Nagraj, G.M.

    2013-01-01

    Keenjhar Lake, Pakistan's largest freshwater lake and an important Ramsar site, provides habitat for internationally important water birds. Annually, 385,000 people visit the lake. The lake is threatened by a variety of causes, including industrial and agricultural pollution. To support its

  17. German Migrant Teachers in Australia: Insights into the Largest Cohort of Non-English Speaking Background Teachers

    Science.gov (United States)

    Bense, Katharina

    2015-01-01

    The research reported in this paper investigates the situation of German migrant teachers in Australia. Although German born teachers represent the largest group of non-English speaking background teachers in Australia, there is no study of the circumstances and experiences of these teachers in Australia. This study aims to fill this gap. It…

  18. The Determinants of Bank Internationalisation in Times of Financial Globalisation: Evidence from the World's Largest Banks (1980-2007)

    NARCIS (Netherlands)

    Westerhuis, Gerarda; Mulder, Arjen

    2015-01-01

    This article analyses the determinants of bank internationalisation, of the world's largest banks from the period 1980–2007. The purpose of the article is twofold. First, we show how a mixed-methods research design, in which we combine a variables-based research with three case studies, can

  19. Pay less, take more: the myth of quality of life at the Brazil’s largest drugstore chain counter

    Directory of Open Access Journals (Sweden)

    André Luiz Maranhão de Souza Leão

    2013-06-01

    Full Text Available Considering the role of cultural transformer that the brandoccupies in the contemporary and seeking to delineate the role played bymyth in this construction, we look at Pague Menos, the largest pharmacyretail network in the country, through a qualitative study based on Barthesiansemiology. Our results showed six myths, whose relationships reveal ametanarrative: the quality of life.

  20. Analyzing the Largest Spectroscopic Data Set of Hydrogen-poor Super-luminous Supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yu-Qian; Modjaz, Maryam; Bianco, Federica B., E-mail: YL1260@nyu.edu, E-mail: mmodjaz@nyu.edu [Center for Cosmology and Particle Physics, New York University, 4 Washington Place, New York, NY 10003 (United States)

    2017-08-10

    Super-luminous supernovae (SLSNe) are tremendously luminous explosions whose power sources and progenitors are highly debated. Broad-lined SNe Ic (SNe Ic-bl) are the only type of SNe that are connected with long-duration gamma-ray bursts (GRBs). Studying the spectral similarity and difference between the populations of hydrogen-poor SLSNe (SLSNe Ic) and of hydrogen-poor stripped-envelope core-collapse SNe, in particular SNe Ic and SNe Ic-bl, can provide crucial observations to test predictions of theories based on various power source models and progenitor models. In this paper, we collected all of the published optical spectra of 32 SLSNe Ic, 21 SNe Ic-bl, as well as 17 SNe Ic, quantified their spectral features, constructed average spectra, and compared them in a systematic way using new tools we have developed. We find that SLSNe Ic and SNe Ic-bl, including those connected with GRBs, have comparable widths for their spectral features and average absorption velocities at all phases. Thus, our findings strengthen the connection between SLSNe Ic and GRBs. In particular, SLSNe Ic have average Fe ii λ 5169 absorption velocities of −15,000 ± 2600 km s{sup −1} at 10 days after peak, which are higher than those of SNe Ic by ∼7000 km s{sup −1} on average. SLSNe Ic also have significantly broader Fe ii λ 5169 lines than SNe Ic. Moreover, we find that such high absorption and width velocities of SLSNe Ic may be hard to explain with the interaction model, and none of the 13 SLSNe Ic with measured absorption velocities spanning over 10 days has a convincing flat velocity evolution, which is inconsistent with the magnetar model in one dimension. Lastly, we compare SN 2011kl, the first SN connected with an ultra-long GRB, with the mean spectrum of SLSNe Ic and of SNe Ic-bl.

  1. The Alabama Space and Rocket Center: The Second Decade.

    Science.gov (United States)

    Buckbee, Edward O.

    1983-01-01

    The Alabama Space and Rocket Center in Huntsville, the world's largest rocket and space museum, includes displays illustrating American rocket history, exhibits and demonstrations on rocketry principles and experiences, and simulations of space travel. A new project includes an integrated recreational-educational complex, described in the three…

  2. Stephenson Cancer Center

    Science.gov (United States)

    Stephenson Cancer Center at the University of Oklahoma in Oklahoma City is an NCI-designated cancer center at the forefront of NCI-supported cancer research. Learn more about the Stephenson Cancer Center's mission.

  3. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Education Centers Carbon Monoxide Information Center Carbon Monoxide Information Center En Español The Invisible Killer Carbon monoxide, ... Install one and check its batteries regularly. View Information About CO Alarms Other CO Topics Safety Tips ...

  4. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Education Safety Education Centers Carbon Monoxide Information Center Carbon Monoxide Information Center En Español The Invisible Killer Carbon monoxide, also known as CO, is called the " ...

  5. Determinants of U.S. poison center utilization.

    Science.gov (United States)

    Litovitz, Toby; Benson, Blaine E; Youniss, Jessica; Metz, Edward

    2010-06-01

    High poison center utilization has been associated with decreased emergency department usage and hospitalization rates. However, utilization requires awareness of the poison center. Penetrance, defined as the number of human poison exposures reported to a poison center per 1,000 population, has been used as a marker of poison center awareness. To identify factors that influence poison center penetrance to optimize the life- and cost-saving benefits of poison control centers. Human poison exposures that were reported to the National Poison Data System in 2001 were analyzed to identify and rank factors affecting poison center penetrance. Overall penetrance correlated with pediatric penetrance (R(2) = 0.75, p poison center that were already in or en route to a healthcare facility at the time of the call to the poison center (R(2) = 0.41, p poison center service populations were associated with lower penetrance (R(2) = 0.23, p poison center (multiple regression). Positive predictors included the percentage of the population younger than 5 years, the percentage of the adult population with a bachelor's degree, poison center certification, poison center educator FTEs (full time equivalents), Asian population percentage, and population density. The inverse correlation between pediatric penetrance and healthcare facility utilization supports prior observations of excessive healthcare utilization when a poison center is not called. Since race, language and distance are barriers to poison center utilization, and since healthcare utilization increases when poison center penetrance declines, low penetrance suggests a lack of awareness of the poison center rather than a low incidence of poisonings. Strategies to raise penetrance should be informed by an understanding of the barriers to utilization - language, Black/African American race, distance from the poison center, poverty, and lower education levels.

  6. Libraries as a means for the integration of immigrant populations in Ávila province

    Directory of Open Access Journals (Sweden)

    María Jesús Romera Iruela

    2014-11-01

    Full Text Available Public libraries can be considered as suitable agents and places for the integration of immigrant population. Therefore, services and programs should be developed in order to give an adequate answer to their needs. This article provides some research findings for the information needs of immigrants at Ávila province. These needs are detected from three different perspectives: public libraries, educational centers, and immigrant associations. The data were collected, using ad-hoc questionnaires, in the districts and municipalities with largest immigrant presence. Several intercultural actions directed to the integration of this population are suggested in this research. Thus, amongst others, the need of a Web site with thematic information on the design of cooperative programs on intercultural education between public libraries and scholar libraries, involving both parents of immigrant students and immigrants associations

  7. Occurrence and fate of steroid estrogens in the largest wastewater treatment plant in Beijing, China.

    Science.gov (United States)

    Zhou, Yiqi; Zha, Jinmiao; Wang, Zijian

    2012-11-01

    Concern over steroid estrogens has increased rapidly in recent years due to their adverse health effects. Effluent discharge from wastewater treatment plants (WWTPs) is the main pollutant source for environmental water. To understand the pollutant level and fate of steroid estrogens in WWTPs, the occurrence of estrone (E1), 17-β-estradiol (E2), estriol (E3), and 17-β-ethinylestradiol (EE2) was investigated in the Gaobeidian WWTP in Beijing, China. Water samples from influent as well as effluent from second sedimentation tanks and advanced treatment processes were taken monthly during 2006 to 2007. In influent, steroid estrogen concentrations varied from 11.6 to 1.1 × 10(2) ng/l, 3.7 to 1.4 × 10(2) ng/l, no detection (nd) to 7.6×10(2) ng/l and nd to 3.3 × 10(2) ng/l for E1, E2, E3, and EE2, respectively. Compared with documented values, the higher steroid estrogen concentrations in the WWTP influent may be due to higher population density, higher birthrate, less dilution, and different sampling time. Results revealed that a municipal WWTP with an activated sludge system incorporating anaerobic, anoxic, and aerobic processes could eliminate natural and synthetic estrogens effectively. The mean elimination efficiencies were 83.2%, 96.4%, 98.8%, and 93.0% for E1, E2, E3, and EE2, respectively. The major removal mechanism for natural estrogens and synthetic estrogen EE2 were biodegradation and sorption on the basis of mass balance in water, suspension particles, and sludge. In the WWTP effluent, however, the highest concentrations of E1, E2, E3, and EE2 attained were 74.2, 3.9, 5.1, and 4.6 ng/l, respectively. This is concerning as residual steroid estrogens in WWTP effluent could lead to pollution of the receiving water. Advanced flocculation treatment was applied in the WWTP and transformed the residual estrogen conjugates to free species, which were reduced further by filtration with removal shifting from 32% to 57% for natural estrogen, although no EE2 was

  8. Womens Business Center

    Data.gov (United States)

    Small Business Administration — Women's Business Centers (WBCs) represent a national network of nearly 100 educational centers throughout the United States and its territories, which are designed...

  9. The Novarupta-Katmai eruption of 1912 - largest eruption of the twentieth century; centennial perspectives

    Science.gov (United States)

    Hildreth, Wes; Fierstein, Judy

    2012-01-01

    , nine packages of ash flows, and three lava domes that followed the explosive pyroclastic episodes. Changes in the proportions of coerupting rhyolite, dacite, and andesite pumice documented for the fallout and ash-flow successions, which are locally interbedded, permit close correlation of those synchronously emplaced sequences and their varied facies. Petrological correlation of the sequence of deposits near Novarupta with ash layers at Kodiak village, 170 km downwind, where three episodes of ashfall were recorded (to the hour), provides key constraints on timing of the eruptive events. Syneruptive collapse of a kilometer-deep caldera took place atop Mount Katmai, a stratovolcano centered 10 km east of the eruption site at Novarupta, owing to drainage of magma from beneath the Katmai edifice. Correlation of ~50 earthquakes recorded at distant seismic stations (including 14 shocks of magnitude 6.0 to 7.0) to fitful caldera collapse provides further constraints on eruption timing, because layers of nonjuvenile breccia and mud ejected from Mount Katmai during collapse pulses are intercalated with the pumice-fall layers from Novarupta. Structure of the Novarupta vent, a 2-km-wide depression backfilled by welded tuff and inferred to be funnel-shaped at depth, is described in detail, as is the 4-km-wide caldera at Mount Katmai. Discussions are also provided concerning: (1) the impact on global climate of the great mass of sulfur-poor but halogen-rich aerosol ejected into the atmosphere by the rhyolite-dominated eruption; (2) chemical and mineralogical effects of the fumarolic acid gases; and (3) the timing of several syneruptive landslide deposits sandwiched within the pumice-fall sequence. Secondary posteruption phenomena characterized include impounded lakes, ash-rich debris flows, phreatic craters on the ignimbrite sheet, responses of glaciers to the fallout blanket and to beheading by caldera collapse, growth of new glaciers inside the caldera, and gradual filling of the

  10. Subset selection for an epsilon-best population : efficiency results

    NARCIS (Netherlands)

    Laan, van der P.

    1991-01-01

    An almost best or an \\epsilon-best population is defined as a population with location parameter on a distance not larger than \\epsilon (\\geq 0) from the best population (with largest value of the location parameter). For the subset selection tables with the relative efficiency of selecting an

  11. The largest Fresco in Europe on cooling tower of nuclear power station of Cruas Meysse in Ardeche, France

    International Nuclear Information System (INIS)

    Di Mayo, J.L.

    1993-01-01

    The Nuclear Power Station Cruas Meysse is on the most important communication way of France, in the Rhone Valley, between the Rhin and the Mediterranean Sea. In the South of the Rhone Valley, the Nuclear Power Plant is situated near the very important site of 'Tricastin', the largest nuclear area in France. Cruas Meysse has a very good integration to the economy, social, and cultural scheme ; that's why EDF and the Ardeche Department had enter into partnership to associate art and technology of our time, and offer a work for everybody - 'Le Verseau' is the largest fresco in Europe - It gives a gigantic signalling system to the Ardeche Department, because the Nuclear Power Station has a very interesting position, close the motor way A7, the National 7 road, and the way of high speed train (TGV) an another symbol of the high French technology

  12. The Largest Bio-Silica Structure on Earth: The Giant Basal Spicule from the Deep-Sea Glass Sponge Monorhaphis chuni

    Directory of Open Access Journals (Sweden)

    Xiaohong Wang

    2011-01-01

    Full Text Available The depth of the ocean is plentifully populated with a highly diverse fauna and flora, from where the Challenger expedition (1873–1876 treasured up a rich collection of vitreous sponges [Hexactinellida]. They have been described by Schulze and represent the phylogenetically oldest class of siliceous sponges [phylum Porifera]; they are eye-catching because of their distinct body plan, which relies on a filigree skeleton. It is constructed by an array of morphologically determined elements, the spicules. Later, during the German Deep Sea Expedition “Valdivia” (1898-1899, Schulze could describe the largest siliceous hexactinellid sponge on Earth, the up to 3 m high Monorhaphis chuni, which develops the equally largest bio-silica structures, the giant basal spicules (3 m × 10 mm. With such spicules as a model, basic knowledge on the morphology, formation, and development of the skeletal elements could be elaborated. Spicules are formed by a proteinaceous scaffold which mediates the formation of siliceous lamellae in which the proteins are encased. Up to eight hundred 5 to 10 μm thick lamellae can be concentrically arranged around an axial canal. The silica matrix is composed of almost pure silicon and oxygen, providing it with unusual optophysical properties that are superior to those of man-made waveguides. Experiments indicated that the spicules function in vivo as a nonocular photoreception system. In addition, the spicules have exceptional mechanical properties, combining mechanical stability with strength and stiffness. Like demosponges the hexactinellids synthesize their silica enzymatically, via the enzyme silicatein. All these basic insights will surely contribute also to a further applied utilization and exploration of bio-silica in material/medical science.

  13. The largest Bio-Silica Structure on Earth: The Giant Basal Spicule from the Deep-Sea Glass Sponge Monorhaphis chuni.

    Science.gov (United States)

    Wang, Xiaohong; Gan, Lu; Jochum, Klaus P; Schröder, Heinz C; Müller, Werner E G

    2011-01-01

    The depth of the ocean is plentifully populated with a highly diverse fauna and flora, from where the Challenger expedition (1873-1876) treasured up a rich collection of vitreous sponges [Hexactinellida]. They have been described by Schulze and represent the phylogenetically oldest class of siliceous sponges [phylum Porifera]; they are eye-catching because of their distinct body plan, which relies on a filigree skeleton. It is constructed by an array of morphologically determined elements, the spicules. Later, during the German Deep Sea Expedition "Valdivia" (1898-1899), Schulze could describe the largest siliceous hexactinellid sponge on Earth, the up to 3 m high Monorhaphis chuni, which develops the equally largest bio-silica structures, the giant basal spicules (3 m × 10 mm). With such spicules as a model, basic knowledge on the morphology, formation, and development of the skeletal elements could be elaborated. Spicules are formed by a proteinaceous scaffold which mediates the formation of siliceous lamellae in which the proteins are encased. Up to eight hundred 5 to 10 μm thick lamellae can be concentrically arranged around an axial canal. The silica matrix is composed of almost pure silicon and oxygen, providing it with unusual optophysical properties that are superior to those of man-made waveguides. Experiments indicated that the spicules function in vivo as a nonocular photoreception system. In addition, the spicules have exceptional mechanical properties, combining mechanical stability with strength and stiffness. Like demosponges the hexactinellids synthesize their silica enzymatically, via the enzyme silicatein. All these basic insights will surely contribute also to a further applied utilization and exploration of bio-silica in material/medical science.

  14. Invasive fish species in the largest lakes of Scotland, Northern Ireland, Wales and England: the collective U.K. experience

    OpenAIRE

    Winfield, I.J.; Fletcher, J.M.; James, J.B.

    2011-01-01

    An invasive species is defined as an alien (or introduced or non-native) species whose establishment and spread threaten ecosystems, habitats or species with harm. Such threats to UK lake fish communities have long been appreciated and this review assembles case histories, including new data, from the largest lakes of Scotland, Northern Ireland, Wales and England to examine the hypothesis that at least some of these introductions have become invasive. Loch Lomond in Scotland has experienced s...

  15. Survival of Extremely Premature Infants at the Largest MOH Referral Hospital in UAE: Comparable Results to Developed Countries

    OpenAIRE

    YASEEN, Hakam; YASEEN, Hoda

    2010-01-01

    Objective: to investigate the survival rate of extreme premature infants born between 2000 and 2008 at AL Qassimi hospital that is the largest Ministry of Health (MOH) referral hospital in the United Arab Emirates (UAE).Methods: This was an institutional review board approved retrospective study of the outcomes of pregnancies in women who were in labor and delivered between 23 and 25 weeks' completed gestation at Al Qassimi Hospital in the Emirate of Sharjah between January 1,2000 and De...

  16. Mapping Dynamics of Inundation Patterns of Two Largest River-Connected Lakes in China: A Comparative Study

    OpenAIRE

    Guiping Wu; Yuanbo Liu

    2016-01-01

    Poyang Lake and Dongting Lake are the two largest freshwater lakes in China. The lakes are located approximately 300 km apart on the middle reaches of the Yangtze River and are differently connected through their respective tributary systems, which will lead to different river–lake water exchanges and discharges. Thus, differences in their morphological and hydrological conditions should induce individual lake spatio-temporal inundation patterns. Quantitative comparative analyses of the dynam...

  17. The largest forest fires in Portugal: the constraints of burned area size on the comprehension of fire severity.

    Science.gov (United States)

    Tedim, Fantina; Remelgado, Ruben; Martins, João; Carvalho, Salete

    2015-01-01

    Portugal is a European country with highest forest fires density and burned area. Since beginning of official forest fires database in 1980, an increase in number of fires and burned area as well as appearance of large and catastrophic fires have characterized fire activity in Portugal. In 1980s, the largest fires were just a little bit over 10,000 ha. However, in the beginning of 21st century several fires occurred with a burned area over 20,000 ha. Some of these events can be classified as mega-fires due to their ecological and socioeconomic severity. The present study aimed to discuss the characterization of large forest fires trend, in order to understand if the largest fires that occurred in Portugal were exceptional events or evidences of a new trend, and the constraints of fire size to characterize fire effects because, usually, it is assumed that larger the fire higher the damages. Using Portuguese forest fire database and satellite imagery, the present study showed that the largest fires could be seen at the same time as exceptional events and as evidence of a new fire regime. It highlighted the importance of size and patterns of unburned patches within fire perimeter as well as heterogeneity of fire ecological severity, usually not included in fire regime description, which are critical to fire management and research. The findings of this research can be used in forest risk reduction and suppression planning.

  18. Time compression of soil erosion by the effect of largest daily event. A regional analysis of USLE database.

    Science.gov (United States)

    Gonzalez-Hidalgo, J. C.; Batalla, R.; Cerda, A.; de Luis, M.

    2009-04-01

    When Thornes and Brunsden wrote in 1977 "How often one hears the researcher (and no less the undergraduate) complain that after weeks of observation "nothing happened" only to learn that, the day after his departure, a flood caused unprecedent erosion and channel changes!" (Thornes and Brunsden, 1977, p. 57), they focussed on two different problems in geomorphological research: the effects of extreme events and the temporal compression of geomorphological processes. The time compression is one of the main characteristic of erosion processes. It means that an important amount of the total soil eroded is produced in very short temporal intervals, i.e. few events mostly related to extreme events. From magnitude-frequency analysis we know that few events, not necessarily extreme by magnitude, produce high amount of geomorphological work. Last but not least, extreme isolated events are a classical issue in geomorphology by their specific effects, and they are receiving permanent attention, increased at present because of scenarios of global change. Notwithstanding, the time compression of geomorphological processes could be focused not only on the analysis of extreme events and the traditional magnitude-frequency approach, but on new complementary approach based on the effects of largest events. The classical approach define extreme event as a rare event (identified by its magnitude and quantified by some deviation from central value), while we define largest events by the rank, whatever their magnitude. In a previous research on time compression of soil erosion, using USLE soil erosion database (Gonzalez-Hidalgo et al., EGU 2007), we described a relationship between the total amount of daily erosive events recorded by plot and the percentage contribution to total soil erosion of n-largest aggregated daily events. Now we offer a further refined analysis comparing different agricultural regions in USA. To do that we have analyzed data from 594 erosion plots from USLE

  19. Economic viability of geriatric hip fracture centers.

    Science.gov (United States)

    Clement, R Carter; Ahn, Jaimo; Mehta, Samir; Bernstein, Joseph

    2013-12-01

    Management of geriatric hip fractures in a protocol-driven center can improve outcomes and reduce costs. Nonetheless, this approach has not spread as broadly as the effectiveness data would imply. One possible explanation is that operating such a center is not perceived as financially worthwhile. To assess the economic viability of dedicated hip fracture centers, the authors built a financial model to estimate profit as a function of costs, reimbursement, and patient volume in 3 settings: an average US hip fracture program, a highly efficient center, and an academic hospital without a specific hip fracture program. Results were tested with sensitivity analysis. A local market analysis was conducted to assess the feasibility of supporting profitable hip fracture centers. The results demonstrate that hip fracture treatment only becomes profitable when the annual caseload exceeds approximately 72, assuming costs characteristic of a typical US hip fracture program. The threshold of profitability is 49 cases per year for high-efficiency hip fracture centers and 151 for the urban academic hospital under review. The largest determinant of profit is reimbursement, followed by costs and volume. In the authors’ home market, 168 hospitals offer hip fracture care, yet 85% fall below the 72-case threshold. Hip fracture centers can be highly profitable through low costs and, especially, high revenues. However, most hospitals likely lose money by offering hip fracture care due to inadequate volume. Thus, both large and small facilities would benefit financially from the consolidation of hip fracture care at dedicated hip fracture centers. Typical US cities have adequate volume to support several such centers.

  20. Comparison of the New Adult Ventilator-Associated Event Criteria to the Centers for Disease Control and Prevention Pediatric Ventilator-Associated Pneumonia Definition (PNU2) in a Population of Pediatric Traumatic Brain Injury Patients.

    Science.gov (United States)

    Cirulis, Meghan M; Hamele, Mitchell T; Stockmann, Chris R; Bennett, Tellen D; Bratton, Susan L

    2016-02-01

    The new Centers for Disease Control and Prevention paradigm for ventilator-associated events is intended to simplify surveillance of infectious and noninfectious complications of mechanical ventilation in adults. We assessed the ventilator-associated events algorithm in pediatric patients. A retrospective observational cohort study. This single-center study took place in a PICU at an urban academic medical facility. Pediatric (ages 0-18 yr old) trauma patients with moderate-to-severe traumatic brain injury ventilated for greater than or equal to 2 days. We assessed for pediatric ventilator-associated pneumonia (as defined by current Centers for Disease Control and Prevention PNU2 guidelines), adult ventilator-associated events, and an experimental ventilator-associated events definition modified for pediatric patients. We compared ventilator-associated events to ventilator-associated pneumonia to calculate the test characteristics. Thirty-nine of 119 patients (33%) developed ventilator-associated pneumonia. Sensitivity of the adult ventilator-associated condition definition was 23% (95% CI, 11-39%), which increased to 56% (95% CI, 40-72%) using the modified pediatric ventilator-associated pneumonia criterion. Specificity reached 100% for both original and modified pediatric probable ventilator-associated pneumonia using ventilator-associated events criteria. Children who developed ventilator-associated pneumonia or ventilator-associated condition had similar baseline characteristics: age, mechanism of injury, injury severity scores, and use of an intracranial pressure monitor. Diagnosis of ventilator-associated pneumonia and ventilator-associated condition portended similarly unfavorable outcomes: longer median duration of ventilation, ICU and hospital length of stay, and more discharges to rehabilitation, home health, or nursing care compared with patients with no pulmonary complication. Both current and modified ventilator-associated events criteria have poor

  1. An Innovative Mobile Health System to Improve and Standardize Antenatal Care Among Underserved Communities: A Feasibility Study in an Italian Hosting Center for Asylum Seekers.

    Science.gov (United States)

    Borsari, Lucia; Stancanelli, Giovanna; Guarenti, Laura; Grandi, Teresa; Leotta, Serena; Barcellini, Lucia; Borella, Paola; Benski, Anne Caroline

    2017-11-16

    Innovative migrant-friendly tools are needed to assist health personnel manage the high number of pregnancies within reception centers. This study tests functionality and acceptability of a new mHealth system in providing antenatal care amongst migrants. The study, carried out between 2014 and 2016, involved 150 pregnant women residing in the largest European migrant reception center in Sicily. A ticket tracking system assessed the system's functionality and a questionnaire assessed women's acceptability. The system facilitated the collection of clinical data, enabling the creation of electronic patient records and identifying 10% of pregnancies as high-risk. The application's digital format increased health providers' adherence to antenatal-care recommendations, while the graphic interface facilitated women's engagement and retention of the health education modules. The study recorded a 91.9% patient satisfaction rate. The system was efficient in providing comprehensive and high-quality antenatal care amongst migrants, facilitating the continuity of care for a population undergoing frequent relocations.

  2. New Orleans Charity Hospital--your trauma center at work.

    Science.gov (United States)

    Stockinger, Zsolt T; Holloway, Vicki L; McSwain, Norman E; Thomas, Dwayne; Fontenot, Cathi; Hunt, John P; Mederos, Eileen; Hewitt, Robert L

    2004-01-01

    The Medical Center of Louisiana at New Orleans-Charity Hospital stands with pride as one of only two level I trauma centers in the state and one of the largest trauma centers in the United States, seeing over 4,000 trauma patients per year. Despite perennial funding issues, Charity Hospital's Emergency Department treated almost 200,000 patients in 2003. This brief report gives an overview of the emergency- and trauma-related services provided by Charity Hospital and underscores its value as a critical asset to healthcare in the Louisiana.

  3. Communications among data and science centers

    Science.gov (United States)

    Green, James L.

    1990-01-01

    The ability to electronically access and query the contents of remote computer archives is of singular importance in space and earth sciences; the present evaluation of such on-line information networks' development status foresees swift expansion of their data capabilities and complexity, in view of the volumes of data that will continue to be generated by NASA missions. The U.S.'s National Space Science Data Center (NSSDC) manages NASA's largest science computer network, the Space Physics Analysis Network; a comprehensive account is given of the structure of NSSDC international access through BITNET, and of connections to the NSSDC available in the Americas via the International X.25 network.

  4. Population pharmacogenetics of Ibero-Latinoamerican populations (MESTIFAR 2014).

    Science.gov (United States)

    Sosa-Macias, Martha; Moya, Graciela E; LLerena, Adrián; Ramírez, Ronald; Terán, Enrique; Peñas-LLedó, Eva M; Tarazona-Santos, Eduardo; Galaviz-Hernández, Carlos; Céspedes-Garro, Carolina; Acosta, Hildaura

    2015-01-01

    MESTIFAR 2014 28-30 November 2014, Panama City, Panama The CEIBA consortium was created within the Ibero-American network of Pharmacogenetics (RIBEF) to study population pharmacogenetics. The current status of these initiatives and results of the MESTIFAR project were analyzed in Panama, 28-30 November 2014. The MESTIFAR project focused on studying CYPs genetic polymorphisms in populations of different ethnic origin. So far, more than 6000 healthy volunteers have been evaluated, making this one of the largest population pharmacogenomic studies worldwide. Three symposia were organized, 'Pharmacogenetics of indigenous and mestizos populations and its clinical implications', 'Methodological innovation in pharmacogenetics and its application in health', and 'General discussion and concluding remarks', about mechanisms and proposals for training, diffusion of pharmacogenetics for Spanish- and Portuguese-speaking health professionals, and 'bench to bedside' pilot projects.

  5. Population and the World Bank.

    Science.gov (United States)

    Sankaran, S

    1973-12-01

    The World Bank Group regards excessive population growth as the single greatest obstacle to economic and social advance in the underdeveloped world. Since 1969 the Bank and the International Development Agency have provided countries with technical assistance through education, fact-finding, and analysis and given 65.7 million dollars for population projects. These projects, in India, Indonesia, Iran, Jamaica, and Malaysia provide training centers, population education, research, and evaluation as well as actual construction of clinics and mobile units. Because population planning touches sensitive areas of religion, caste, race, morality, and politics, the involved nation's political commitment to plan population growth is critical to the success of any program.

  6. Hanford Area 2000 Population

    International Nuclear Information System (INIS)

    Elliott, Douglas B.; Scott, Michael J.; Antonio, Ernest J.; Rhoads, Kathleen

    2004-01-01

    This report was prepared for the U.S. Department of Energy (DOE) Richland Operations Office, Surface Environmental Surveillance Project, to provide demographic data required for ongoing environmental assessments and safety analyses at the DOE Hanford Site near Richland, Washington. This document includes 2000 Census estimates for the resident population within an 80-kilometer (50-mile) radius of the Hanford Site. Population distributions are reported relative to five reference points centered on meteorological stations within major operating areas of the Hanford Site - the 100 F, 100 K, 200, 300, and 400 Areas. These data are presented in both graphical and tabular format, and are provided for total populations residing within 80 km (50 mi) of the reference points, as well as for Native American, Hispanic and Latino, total minority, and low-income populations

  7. Largest terrestrial electromagnetic pulsar

    Czech Academy of Sciences Publication Activity Database

    Pardy, Miroslav

    2002-01-01

    Roč. 46, č. 6 (2002), s. 1155-1163 ISSN 0020-7748 R&D Projects: GA MŠk LN00A100 Institutional research plan: CEZ:AV0Z2043910 Keywords : source theory, spectral formula, synchrotron radiation Subject RIV: BE - Theoretical Physics Impact factor: 0.655, year: 2002

  8. Stent thrombosis and bleeding complications after implantation of sirolimus-eluting coronary stents in an unselected worldwide population: a report from the e-SELECT (Multi-Center Post-Market Surveillance) registry.

    Science.gov (United States)

    Urban, Philip; Abizaid, Alexandre; Banning, Adrian; Bartorelli, Antonio L; Baux, Ana Cebrian; Džavík, Vladimír; Ellis, Stephen; Gao, Runlin; Holmes, David; Jeong, Myung Ho; Legrand, Victor; Neumann, Franz-Josef; Nyakern, Maria; Spaulding, Christian; Worthley, Stephen

    2011-03-29

    The aim of this study was to ascertain the 1-year incidence of stent thrombosis (ST) and major bleeding (MB) in a large, unselected population treated with sirolimus-eluting stents (SES). Stent thrombosis and MB are major potential complications of drug-eluting stent implantation. Their relative incidence and predisposing factors among large populations treated worldwide are unclear. The SES were implanted in 15,147 patients who were entered in a multinational registry. We analyzed the incidence of: 1) definite and probable ST as defined by the Academic Research Consortium; and 2) MB, with the STEEPLE (Safety and efficacy of Enoxaparin in PCI) definition, together with their relation to dual antiplatelet therapy (DAPT) and to 1-year clinical outcomes. The mean age of the sample was 62 ± 11 years, 30.4% were diabetic, 10% had a Charlson comorbidity index ≥3, and 44% presented with acute coronary syndrome or myocardial infarction. At 1 year, the reported compliance with DAPT as recommended by the European Society of Cardiology guidelines was 86.3%. Adverse event rates were: ST 1.0%, MB 1.0%, mortality 1.7%, myocardial infarction 1.9%, and target lesion revascularization 2.3%. Multivariate analysis identified 9 correlates of ST and 4 correlates of MB. Advanced age and a high Charlson index were associated with an increased risk of both ST and MB. After ST, the 7-day and 1-year all-cause mortality was 30% and 35%, respectively, versus 1.5% and 10% after MB. Only 2 of 13,749 patients (0.015%) experienced both MB and ST during the entire 1-year follow-up period. In this worldwide population treated with ≥1 SES, the reported compliance with DAPT was good, and the incidence of ST and MB was low. Stent thrombosis and MB very rarely occurred in the same patient. (The e-SELECT Registry: a Multicenter Post-Market Surveillance; NCT00438919). Copyright © 2011 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  9. World's largest DC flywheel generator for the toroidal field power supply of JAERI's JFT-2M Tokamak nuclear fusion reactor

    International Nuclear Information System (INIS)

    Tani, Takashi; Nakanishi, Yuji; Horita, Tsuyoshi; Kawase, Chiharu; Oyabu, Isao; Kishimoto, Takeshi.

    1996-01-01

    Mitsubishi Electric has delivered the world's largest DC generator for the toroidal field coil power supply of the JFT-2M Tokamak at the Japan Atomic Energy Research Institute. The unit rotates at 225 or 460 rpm, providing a maximum rated output of 2,700 V, 19,000 A and 51.3 MW. The toroidal field is a DC field, so use of a DC generator permits a simpler design consuming less floor space than an AC drive system. The generator was manufactured following extensive studies on commutation, mechanical strength and insulation. (author)

  10. Does gender affect funding success at the peer-to-peer credit markets? Evidence from the largest German lending platform

    OpenAIRE

    Barasinska, Nataliya; Schäfer, Dorothea

    2010-01-01

    Studies of peer-to-peer lending in the USA find that female borrowers have better chances of getting funds than males. Is differential treatment of borrowers of different sexes a common feature of peer-to-peer lendingmarkets or is it subject to specific businessmodels, ways of fixing loan contracts and even national financial systems? We aim at answering this question by providing evidence on loan procurement at the largest German peer-to-peer lending platform Smava.de. Our results show that ...

  11. Fluctuations in the size of the largest projectile fragment produced in 1 GeV/nucleon Au + C collisions

    International Nuclear Information System (INIS)

    Warren, P.; Elliott, J.B.; Gilkes, M.L.; Hauger, A.; Hirsch, A.S.

    1993-01-01

    Large fluctuations in quantities such as density are characteristic of critical phenomena in the neighborhood of the critical point. Using the EOS apparatus at the Bevalac, we have performed an exclusive experiment in which the size of the largest projectile fragment produced in 1 GeV/nucleon Au+C collisions is studied as a function of the charged multiplicity of the event. A peak in the fluctuations is expected at the critical multiplicity. The data are compared to a percolation model and a statistical multifragmentation model

  12. Global CO_2-energy emissions in 2007. China becomes the largest emitter along with the United States - June 2008

    International Nuclear Information System (INIS)

    2008-01-01

    China becomes the largest emitter along with the United States. Contents: 1990-2007 evolution (key figures of Yearly average evolutions); Global CO_2-energy emissions in 2007: 27,3 GtCO_2; Global CO_2-energy emissions have increased by 3,2% in 2007, largely driven by China. Since 1990, China has more than doubled its CO_2-energy emissions, to reach the same emission level as the USA in 2007. Two very contrasting tendencies appear since 1990: stabilization of emissions in Annex B countries, boom in China and India. Since 1990, more than half of CO_2-energy emissions growth is (logically) due to coal. (authors)

  13. Population Research.

    Science.gov (United States)

    National Inst. of Child Health and Human Development (NIH), Bethesda, MD.

    The scope of population research as carried on by the National Institute of Child Health and Human Development (NICHD) is set forth in this booklet. Population problems of the world, United States, and the individual are considered along with international population policies based on voluntary family planning programs. NICHD goals for biological…

  14. Medical Toxicology and Public Health-Update on Research and Activities at the Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry : Environmental Exposures among Arctic Populations: The Maternal Organics Monitoring Study in Alaska.

    Science.gov (United States)

    Anwar, Mehruba; Ridpath, Alison; Berner, James; Schier, Joshua G

    2016-09-01

    Evidence suggests that in-utero exposure to environmental chemicals, such as persistent organic pollutants (POPs), heavy metals, and radionuclides, that might bioaccumulate in the mother may increase a newborn's risk of adverse developmental, neurological, and immunologic effects. Chemical contamination of bodies of water and strong ocean currents worldwide can drive these chemicals from lower latitudes to Arctic waters where they accumulate in common traditional subsistence foods. In response to concerns of the people from Alaska of the effects of bio-accumulated chemicals on their children, the Maternal Organics Monitoring Study(MOMS) was developed. The objective of the study was to assess the risks and benefits associated with the population's subsistence diet. Data analysis of biological samples at the CDC's NCEH laboratory and maternal questionnaires is ongoing. Results will be provided to Alaska Native communities to help support public health actions and inform future interventions and research.

  15. Intra-session test-retest reliability of magnitude and structure of center of pressure from the Nintendo Wii Balance Board™ for a visually impaired and normally sighted population.

    Science.gov (United States)

    Jeter, Pamela E; Wang, Jiangxia; Gu, Jialiang; Barry, Michael P; Roach, Crystal; Corson, Marilyn; Yang, Lindsay; Dagnelie, Gislin

    2015-02-01

    Individuals with visual impairment (VI) have irreparable damage to one of the input streams contributing to postural stability. Here, we evaluated the intra-session test-retest reliability of the Wii Balance Board (WBB) for measuring Center of Pressure (COP) magnitude and structure, i.e. approximate entropy (ApEn) in fourteen legally blind participants and 21 participants with corrected-to-normal vision. Participants completed a validated balance protocol which included four sensory conditions: double-leg standing on a firm surface with eyes open (EO-firm); a firm surface with eyes closed (EC-firm); a foam surface with EO (EO-foam); and a foam surface with EC (EC-foam). Participants performed the full balance protocol twice during the session, separated by a period of 15min, to determine the intraclass correlation coefficient (ICC). Absolute reliability was determined by the standard error of measurement (SEM). The minimal difference (MD) was estimated to determine clinical significance for future studies. COP measures were derived from data sent by the WBB to a laptop via Bluetooth. COP scores increased with the difficulty of sensory condition indicating WBB sensitivity (all pbalance impairment among VI persons. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. U.S. Population Data 1969-2016 - SEER Population Data

    Science.gov (United States)

    Download county population estimates used in SEER*Stat to calculate cancer incidence and mortality rates. The estimates are a modification of the U.S. Census Bureau's Population Estimates Program, in collaboration with National Center for Health Statistics.

  17. Tornadoes: A Center Approach.

    Science.gov (United States)

    Christman-Rothlein, Liz; Meinbach, Anita M.

    1981-01-01

    Information is given on how to put together a learning center. Discusses information and activity packets for a complete learning center on tornadoes including objectives, directions, materials, photographs of physical arrangements, and posttest. (DC)

  18. Tehran Nuclear Research Center

    International Nuclear Information System (INIS)

    Taherzadeh, M.

    1977-01-01

    The Tehran Nuclear Research Center was formerly managed by the University of Tehran. This Center, after its transformation to the AEOI, has now become a focal point for basic research in the area of Nuclear Energy in Iran

  19. Day Care Centers

    Data.gov (United States)

    Department of Homeland Security — This database contains locations of day care centers for 50 states and Washington D.C. and Puerto Rico. The dataset only includes center based day care locations...

  20. Center for Functional Nanomaterials

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Functional Nanomaterials (CFN) explores the unique properties of materials and processes at the nanoscale. The CFN is a user-oriented research center...

  1. Hydrologic Engineering Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Hydrologic Engineering Center (HEC), an organization within the Institute for Water Resources, is the designated Center of Expertise for the U.S. Army Corps of...

  2. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... OnSafety Blog Safety Education Centers Neighborhood Safety Network Community Outreach Resource Center Toy Recall Statistics CO Poster ... Sitemap RSS E-mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information ( ...

  3. MARYLAND ROBOTICS CENTER

    Data.gov (United States)

    Federal Laboratory Consortium — The Maryland Robotics Center is an interdisciplinary research center housed in the Institute for Systems Research (link is external)within the A. James Clark School...

  4. Find a Health Center

    Data.gov (United States)

    U.S. Department of Health & Human Services — HRSA Health Centers care for you, even if you have no health insurance – you pay what you can afford based on your income. Health centers provide services that...

  5. NIH Clinical Centers

    Data.gov (United States)

    Federal Laboratory Consortium — The NIH Clinical Center consists of two main facilities: The Mark O. Hatfield Clinical Research Center, which opened in 2005, houses inpatient units, day hospitals,...

  6. Genetic Science Learning Center

    Science.gov (United States)

    Genetic Science Learning Center Making science and health easy for everyone to understand Home News Our Team What We Do ... Collaboration Conferences Current Projects Publications Contact The Genetic Science Learning Center at The University of Utah is a ...

  7. Poison Control Centers

    Science.gov (United States)

    ... 1222 immediately. Name State American Association of Poison Control Centers Address AAPCC Central Office NOT A POISON ... not for emergency use. Arkansas ASPCA Animal Poison Control Center Address 1717 S. Philo Road, Suite 36 Urbana, ...

  8. Distribution of the largest aftershocks in branching models of triggered seismicity: Theory of the universal Baath law

    International Nuclear Information System (INIS)

    Saichev, A.; Sornette, D.

    2005-01-01

    Using the epidemic-type aftershock sequence (ETAS) branching model of triggered seismicity, we apply the formalism of generating probability functions to calculate exactly the average difference between the magnitude of a mainshock and the magnitude of its largest aftershock over all generations. This average magnitude difference is found empirically to be independent of the mainshock magnitude and equal to 1.2, a universal behavior known as Baath's law. Our theory shows that Baath's law holds only sufficiently close to the critical regime of the ETAS branching process. Allowing for error bars ±0.1 for Baath's constant value around 1.2, our exact analytical treatment of Baath's law provides new constraints on the productivity exponent α and the branching ratio n: 0.9 < or approx. α≤1 and 0.8 < or approx. n≤1. We propose a method for measuring α based on the predicted renormalization of the Gutenberg-Richter distribution of the magnitudes of the largest aftershock. We also introduce the 'second Baath law for foreshocks': the probability that a main earthquake turns out to be the foreshock does not depend on its magnitude ρ

  9. The Process of Leadership and the Organizational Knowledge Management: the practicy of the largest industries of Santa Catarina

    Directory of Open Access Journals (Sweden)

    Dante Marciano Girardi

    2012-04-01

    Full Text Available DOI: http://dx.doi.org/10.5007/2175-8077.2012v14n32p65 The aim of this article is to introduce the practices of leadership in the largest industries of Santa Catarina and their contribution to the Knowledge Management. The organization competitiveness is related to the people and to the capacity of the companies to improve the constant development of knowledge. Using the leadership, the managers and the People Management have created compromise and improved the results of the organizations. The adopted methodology followed the qualitative methodology, descriptive and applied research. There were interviewed the seven largest industries of the state of Santa Catarina, in number of collaborators. The data were analyzed by the technique of analysis of content. It has been observed that the leadership is present in the most of the studied companies, by the use of formal programs of development of leaders or of actions related to leadership. It is concluded that the companies have the focus in the people and in the knowledge, in bigger or smaller degree, but some of them are in phase of transition and revision of programs towards the development of their talents and of the Knowledge Management.

  10. Application of the largest Lyapunov exponent and non-linear fractal extrapolation algorithm to short-term load forecasting

    International Nuclear Information System (INIS)

    Wang Jianzhou; Jia Ruiling; Zhao Weigang; Wu Jie; Dong Yao

    2012-01-01

    Highlights: ► The maximal predictive step size is determined by the largest Lyapunov exponent. ► A proper forecasting step size is applied to load demand forecasting. ► The improved approach is validated by the actual load demand data. ► Non-linear fractal extrapolation method is compared with three forecasting models. ► Performance of the models is evaluated by three different error measures. - Abstract: Precise short-term load forecasting (STLF) plays a key role in unit commitment, maintenance and economic dispatch problems. Employing a subjective and arbitrary predictive step size is one of the most important factors causing the low forecasting accuracy. To solve this problem, the largest Lyapunov exponent is adopted to estimate the maximal predictive step size so that the step size in the forecasting is no more than this maximal one. In addition, in this paper a seldom used forecasting model, which is based on the non-linear fractal extrapolation (NLFE) algorithm, is considered to develop the accuracy of predictions. The suitability and superiority of the two solutions are illustrated through an application to real load forecasting using New South Wales electricity load data from the Australian National Electricity Market. Meanwhile, three forecasting models: the gray model, the seasonal autoregressive integrated moving average approach and the support vector machine method, which received high approval in STLF, are selected to compare with the NLFE algorithm. Comparison results also show that the NLFE model is outstanding, effective, practical and feasible.

  11. Data Center Tasking.

    Science.gov (United States)

    Temares, M. Lewis; Lutheran, Joseph A.

    Operations tasking for data center management is discussed. The original and revised organizational structures of the data center at the University of Miami are also described. The organizational strategy addresses the functions that should be performed by the data center, anticipates the specialized skills required, and addresses personnel…

  12. Center of buoyancy definition

    International Nuclear Information System (INIS)

    Sandberg, V.

    1988-12-01

    The center of buoyancy of an arbitrary shaped body is defined in analogy to the center of gravity. The definitions of the buoyant force and center of buoyancy in terms of integrals over the area of the body are converted to volume integrals and shown to have simple intuitive interpretations

  13. Wound care centers

    Science.gov (United States)

    Pressure ulcer - wound care center; Decubitus ulcer - wound care center; Diabetic ulcer - wound care center; Surgical wound - wound ... Common types of non-healing wounds include: Pressure sores Surgical ... flow, or swollen legs Certain wounds may not heal well due to: ...

  14. Nuclear Reaction Data Centers

    International Nuclear Information System (INIS)

    McLane, V.; Nordborg, C.; Lemmel, H.D.; Manokhin, V.N.

    1988-01-01

    The cooperating Nuclear Reaction Data Centers are involved in the compilation and exchange of nuclear reaction data for incident neutrons, charged particles and photons. Individual centers may also have services in other areas, e.g., evaluated data, nuclear structure and decay data, reactor physics, nuclear safety; some of this information may also be exchanged between interested centers. 20 refs., 1 tab

  15. The epidemiological characteristics and genetic diversity of dengue virus during the third largest historical outbreak of dengue in Guangdong, China, in 2014.

    Science.gov (United States)

    Sun, Jiufeng; Wu, De; Zhou, Huiqiong; Zhang, Huan; Guan, Dawei; He, Xiang; Cai, Songwu; Ke, Changwen; Lin, Jinyan

    2016-01-01

    The third largest historical outbreak of dengue occurred during July to December 2014, in 20 of 21 cities of Guangdong, China. The epidemiological and molecular characteristics of the introduction, expansion and phylogeny of the DENV isolates involved in this outbreak were investigated. A combination analyses of epidemiological characteristics and genetic diversity of dengue virus was performed in this study. In total, 45,236 cases and 6 fatalities were reported. Unemployed individuals, retirees and retailers were the most affected populations. A total of 6024 cases were verified to have DENV infections by nucleic acid detection, of which 5947, 74 and 3 were confirmed to have DENV-1, -2, and -3 infections, respectively. Phylogenetic analyses of DENV-1 isolates were assigned into three genotypes (I, IV, and V). Genotype V was the predominant genotype that likely originated from Singapore. The DENV-2 isolates were assigned to the Cosmopolitan and Asian I genotypes. A unique DENV-3 isolate (genotype III) shared high similarity with isolates obtained from Guangdong in 2013. A combination analyses demonstrated the multiple geographical origins of this outbreak, and highlight the importance of early detection, the case management and vector surveillance for preventing further dengue epidemics in Guangdong. Copyright © 2015 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  16. High Prevalence of Multidrug-Resistant Community-Acquired Methicillin-Resistant Staphylococcus aureus at the Largest Veterinary Teaching Hospital in Costa Rica.

    Science.gov (United States)

    Rojas, Irene; Barquero-Calvo, Elías; van Balen, Joany C; Rojas, Norman; Muñoz-Vargas, Lohendy; Hoet, Armando E

    2017-09-01

    Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogen associated with severe infections in companion animals present in the community, and it is diagnosed in animals admitted to veterinary hospitals. However, reports that describe the circulation of MRSA in animal populations and veterinary settings in Latin America are scarce. Therefore, the objective of this study was to determine the prevalence and investigate the molecular epidemiology of MRSA in the environment of the largest veterinary teaching hospital in Costa Rica. Preselected contact surfaces were sampled twice within a 6-week period. Antimicrobial resistance, SCCmec type, Panton-Valentine leukocidin screening, USA type, and clonality were assessed in all recovered isolates. Overall, MRSA was isolated from 26.5% (27/102) of the surfaces sampled, with doors, desks, and examination tables most frequently contaminated. Molecular analysis demonstrated a variety of surfaces from different sections of the hospital contaminated by three highly related clones/pulsotypes. All, but one of the isolates were characterized as multidrug-resistant SCCmec type IV-USA700, a strain sporadically described in other countries and often classified as community acquired. The detection and frequency of this unique strain in this veterinary setting suggest Costa Rica has a distinctive MRSA ecology when compared with other countries/regions. The high level of environmental contamination highlights the necessity to establish and enforce standard cleaning and disinfection protocols to minimize further spread of this pathogen and reduce the risk of nosocomial and/or occupational transmission of MRSA.

  17. Association of green tea consumption with mortality due to all causes and major causes of death in a Japanese population: the Japan Public Health Center-based Prospective Study (JPHC Study).

    Science.gov (United States)

    Saito, Eiko; Inoue, Manami; Sawada, Norie; Shimazu, Taichi; Yamaji, Taiki; Iwasaki, Motoki; Sasazuki, Shizuka; Noda, Mitsuhiko; Iso, Hiroyasu; Tsugane, Shoichiro

    2015-07-01

    We examined the association between green tea consumption and mortality due to all causes, cancer, heart disease, cerebrovascular disease, respiratory disease, injuries, and other causes of death in a large-scale population-based cohort study in Japan. We studied 90,914 Japanese (aged between 40 and 69 years) recruited between 1990 and 1994. After 18.7 years of follow-up, 12,874 deaths were reported. The association between green tea consumption and risk of all causes and major causes of mortality was assessed using the Cox proportional hazards regression model with adjustment for potential confounders. Hazard ratios for all-cause mortality among men who consumed green tea compared with those who drank less than 1 cup/day were 0.96 (0.89-1.03) for 1-2 cups/day, 0.88 (0.82-0.95) for 3-4 cups/day, and 0.87 (0.81-0.94) for more than 5 cups/day (P for trend death in Japan. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Plasma 25-hydroxyvitamin D concentration and subsequent risk of total and site specific cancers in Japanese population: large case-cohort study within Japan Public Health Center-based Prospective Study cohort.

    Science.gov (United States)

    Budhathoki, Sanjeev; Hidaka, Akihisa; Yamaji, Taiki; Sawada, Norie; Tanaka-Mizuno, Sachiko; Kuchiba, Aya; Charvat, Hadrien; Goto, Atsushi; Kojima, Satoshi; Sudo, Natsuki; Shimazu, Taichi; Sasazuki, Shizuka; Inoue, Manami; Tsugane, Shoichiro; Iwasaki, Motoki

    2018-03-07

    To evaluate the association between pre-diagnostic circulating vitamin D concentration and the subsequent risk of overall and site specific cancer in a large cohort study. Nested case-cohort study within the Japan Public Health Center-based Prospective Study cohort. Nine public health centre areas across Japan. 3301 incident cases of cancer and 4044 randomly selected subcohort participants. Plasma concentration of 25-hydroxyvitamin D measured by enzyme immunoassay. Participants were divided into quarters based on the sex and season specific distribution of 25-hydroxyvitamin D among subcohorts. Weighted Cox proportional hazard models were used to calculate the multivariable adjusted hazard ratios for overall and site specific cancer across categories of 25-hydroxyvitamin D concentration, with the lowest quarter as the reference. Incidence of overall or site specific cancer. Plasma 25-hydroxyvitamin D concentration was inversely associated with the risk of total cancer, with multivariable adjusted hazard ratios for the second to fourth quarters compared with the lowest quarter of 0.81 (95% confidence interval 0.70 to 0.94), 0.75 (0.65 to 0.87), and 0.78 (0.67 to 0.91), respectively (P for trend=0.001). Among the findings for cancers at specific sites, an inverse association was found for liver cancer, with corresponding hazard ratios of 0.70 (0.44 to 1.13), 0.65 (0.40 to 1.06), and 0.45 (0.26 to 0.79) (P for trend=0.006). A sensitivity analysis showed that alternately removing cases of cancer at one specific site from total cancer cases did not substantially change the overall hazard ratios. In this large prospective study, higher vitamin D concentration was associated with lower risk of total cancer. These findings support the hypothesis that vitamin D has protective effects against cancers at many sites. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  19. Applications and limitations of Centers for Disease Control and Prevention miniature light traps for measuring biting densities of African malaria vector populations: a pooled-analysis of 13 comparisons with human landing catches.

    Science.gov (United States)

    Briët, Olivier J T; Huho, Bernadette J; Gimnig, John E; Bayoh, Nabie; Seyoum, Aklilu; Sikaala, Chadwick H; Govella, Nicodem; Diallo, Diadier A; Abdullah, Salim; Smith, Thomas A; Killeen, Gerry F

    2015-06-18

    Measurement of densities of host-seeking malaria vectors is important for estimating levels of disease transmission, for appropriately allocating interventions, and for quantifying their impact. The gold standard for estimating mosquito-human contact rates is the human landing catch (HLC), where human volunteers catch mosquitoes that land on their exposed body parts. This approach necessitates exposure to potentially infectious mosquitoes, and is very labour intensive. There are several safer and less labour-intensive methods, with Centers for Disease Control light traps (LT) placed indoors near occupied bed nets being the most widely used. This paper presents analyses of 13 studies with paired mosquito collections of LT and HLC to evaluate these methods for their consistency in sampling indoor-feeding mosquitoes belonging to the two major taxa of malaria vectors across Africa, the Anopheles gambiae sensu lato complex and the Anopheles funestus s.l. group. Both overall and study-specific sampling efficiencies of LT compared with HLC were computed, and regression methods that allow for the substantial variations in mosquito counts made by either method were used to test whether the sampling efficacy varies with mosquito density. Generally, LT were able to collect similar numbers of mosquitoes to the HLC indoors, although the relative sampling efficacy, measured by the ratio of LT:HLC varied considerably between studies. The overall best estimate for An. gambiae s.l. was 1.06 (95% credible interval: 0.68-1.64) and for An. funestus s.l. was 1.37 (0.70-2.68). Local calibration exercises are not reproducible, since only in a few studies did LT sample proportionally to HLC, and there was no geographical pattern or consistent trend with average density in the tendency for LT to either under- or over-sample. LT are a crude tool at best, but are relatively easy to deploy on a large scale. Spatial and temporal variation in mosquito densities and human malaria transmission

  20. Population Viability Analysis of the Endangered Shortnose Sturgeon

    Science.gov (United States)

    2011-12-01

    ll- 1 ) 0.0 0.2 0.4 0.6 0.8 Sturgeon ( left ) Prey ( right ) Figure 11. Model-simulated shortnose sturgeon population dynamics and prey dynamics over a...indicate low substrate diversity dominated by silt/sand substrate. ix ACRONYMS DO Dissolved oxygen DOC Dissolved organic carbon EFDC...fewer fish than the largest known population in the Hudson River ( Bain et al. 2007). Population estimates for this population have varied between 75

  1. Center for Advanced Separation Technology

    Energy Technology Data Exchange (ETDEWEB)

    Honaker, Rick

    2013-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, CAST is now a five-university consortium – Virginia Tech, West Virginia University, University of Kentucky, University of Utah and Montana Tech, - that is supported through U.S. DOE Cooperative Agreement No. DE-FE0000699, Center for Advanced Separation Technology. Much of the research to be conducted with Cooperative Agreement funds will be longer term, high-risk, basic research and will be carried out in two broad areas: Advanced Pre-Combustion Clean Coal Technologies and Gas-Gas Separations. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the five member universities. These were reviewed and the selected proposals were forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed below by category, along with abstracts from their final reports.

  2. Imaginary populations

    OpenAIRE

    Martínez-Abraín, Alejandro

    2010-01-01

    A few years ago, Camus & Lima (2002) wrote an essay to stimulate ecologists to think about how we define and use a fundamental concept in ecology: the population. They concluded, concurring with Berryman (2002), that a population is "a group of individuals of the same species that live together in an area of sufficient size to permit normal dispersal and/or migration behaviour and in which population changes are largely the results of birth and death processes". They pointed out that ecologis...

  3. Assessment of bioaerosol contamination (bacteria and fungi) in the largest urban wastewater treatment plant in the Middle East.

    Science.gov (United States)

    Niazi, Sadegh; Hassanvand, Mohammad Sadegh; Mahvi, Amir Hossein; Nabizadeh, Ramin; Alimohammadi, Mahmood; Nabavi, Samira; Faridi, Sasan; Dehghani, Asghar; Hoseini, Mohammad; Moradi-Joo, Mohammad; Mokamel, Adel; Kashani, Homa; Yarali, Navid; Yunesian, Masud

    2015-10-01

    Bioaerosol concentration was measured in wastewater treatment units in south of Tehran, the largest wastewater treatment plant in the Middle East. Active sampling was carried out around four operational units and a point as background. The results showed that the aeration tank with an average of 1016 CFU/m(3) in winter and 1973 CFU/m(3) in summer had the greatest effect on emission of bacterial bioaerosols. In addition, primary treatment had the highest impact on fungal emission. Among the bacteria, Micrococcus spp. showed the widest emission in the winter, and Bacillus spp. was dominant in summer. Furthermore, fungi such as Penicillium spp. and Cladosporium spp. were the dominant types in the seasons. Overall, significant relationship was observed between meteorological parameters and the concentration of bacterial and fungal aerosols.

  4. Spatial Air Index Based on Largest Empty Rectangles for Non-Flat Wireless Broadcast in Pervasive Computing

    Directory of Open Access Journals (Sweden)

    Jun-Hong Shen

    2016-11-01

    Full Text Available In pervasive computing, location-based services (LBSs are valuable for mobile clients based on their current locations. LBSs use spatial window queries to enable useful applications for mobile clients. Based on skewed access patterns of mobile clients, non-flat wireless broadcast has been shown to efficiently disseminate spatial objects to mobile clients. In this paper, we consider a scenario in which spatial objects are broadcast to mobile clients over a wireless channel in a non-flat broadcast manner to process window queries. For such a scenario, we propose an efficient spatial air index method to handle window query access in non-flat wireless broadcast environments. The concept of largest empty rectangles is used to avoid unnecessary examination of the broadcast content, thus reducing the processing time for window queries. Simulation results show that the proposed spatial air index method outperforms the existing methods under various settings.

  5. An Examination of Strategic Philanthropy and CSR Communication Patterns among the World’s Twenty-One Largest Oil Companies

    Directory of Open Access Journals (Sweden)

    J. Brad Gatlin

    2013-07-01

    Full Text Available Fortune Magazine’s 2012 list of 100 largest companies included 21 oil companies. This paper seeks to discern patterns of those 21 companies’ philanthropic efforts and communication thereof. Specifically, the paper will consider issues such as ownership (all companies were either publicly-traded or state-owned, the economic development of the home country, and the citizens’ expectations of corporate citizens. The philanthropic efforts of all 21 companies are discussed in the context of Porter and Kramer’s (2001 framework of the competitive context It is concluded that the oil industry is particularly well-suited to affect factor and, to a lesser extent, demand conditions, through philanthropic efforts. A model for classifying the philanthropic based on ownership and country conditions is proposed, and suggestions for further research are made.

  6. The Curse of the Gold: Discourses Surrounding the Project of the Largest Pit-mine in Europe

    Directory of Open Access Journals (Sweden)

    Istvan Egresi

    2011-11-01

    Full Text Available In 1996, a Canadian company started geological explorations in the Rosia Montana area in the Romanian Carpathians. Two years later it formed a joint-venture with a Romanian state company to exploit what is believed to be Europe´s largest gold reserves. However, as of June 2011 extraction has not started yet and it may never start due to the opposition of numerous NGO´s that have pointed out the environmental, social and economic unsustainability of this mining project. This situation is highly unusual for a country that is hungry for foreign investment especially since up until very recently the state had supported any project promising to revitalize its mining sector. This paper will investigate the changes in the discourses surrounding this mining project taking into consideration the effects of globalization and the effects of Romania´s EU membership after 2007.

  7. Causes and Consequences of Ownership Concentration among Europe´s Largest Companies: Economic and Systemic Explanations

    DEFF Research Database (Denmark)

    Pedersen, Torben; Thomsen, Steen

    1999-01-01

    The paper examines causes and effects of ownership concentration among the largest companies in 12 European countries. As a reference point the paper takes a seminal empirical study on US data by Demsetz and Lehn (1985) and examines to what extent their model is applicable in European countries....... The findings indicate that both general economic effects and system effects are significant. Ownership concentration is found to decrease with firm size and to increase with earnings volatility. But in support of the system theories advocated by Roe (1991), Laporta et al. (1996) and Shleifer and Vishny (1997......) nationality is also found to have a significant effect which is partly attributable to institutional differences between nations such as stock market size and the frequency of large banks. Finally, in line with Demsetz and Lehn (1985), ownership concentration is found to have an insignificant effect...

  8. POPULATION Total Population NMHD 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The 2006 Second Edition TIGER/Line files are an extract of selected geographic and cartographic information from the Census TIGER database. The geographic coverage...

  9. POPULATION Total Population BGs 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — TIGER, TIGER/Line, and Census TIGER are registered trademarks of the Bureau of the Census. The Redistricting Census 2000 TIGER/Line files are an extract of selected...

  10. POPULATION Total Population COS 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — TIGER, TIGER/Line, and Census TIGER are registered trademarks of the Bureau of the Census. The Redistricting Census 2000 TIGER/Line files are an extract of selected...

  11. POPULATION Total Population CTs 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — TIGER, TIGER/Line, and Census TIGER are registered trademarks of the Bureau of the Census. The Redistricting Census 2000 TIGER/Line files are an extract of selected...

  12. POPULATION Total Population NMSD 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The 2006 Second Edition TIGER/Line files are an extract of selected geographic and cartographic information from the Census TIGER database. The geographic coverage...

  13. China: Awakening Giant Developing Solutions to Population Aging

    Science.gov (United States)

    Zhang, Ning Jackie; Guo, Man; Zheng, Xiaoying

    2012-01-01

    As the world's most populous country with the largest aging population and a rapidly growing economy, China is receiving increased attention from both the Chinese government and the governments of other countries that face low fertility and aging problems. This unprecedented shift of demographic structure has repercussions for many aspects of…

  14. Population and Development: Perspective on a Teaching Challenge.

    Science.gov (United States)

    Dawson, Leslie

    1995-01-01

    Through the World Institute's Curriculum, students can look at the world's two largest nations, China and India, to learn about population and gender equity issues. This article describes the use of recent data gathered by international agencies and population education in the classroom. (LZ)

  15. Population Blocks.

    Science.gov (United States)

    Smith, Martin H.

    1992-01-01

    Describes an educational game called "Population Blocks" that is designed to illustrate the concept of exponential growth of the human population and some potential effects of overpopulation. The game material consists of wooden blocks; 18 blocks are painted green (representing land), 7 are painted blue (representing water); and the remaining…

  16. From the Telescope to the Laboratory and Back Again: The Center for Astrophysical Plasma Properties

    Science.gov (United States)

    Houston Montgomery, Michael; Winget, Don; Schaeuble, Marc; Hawkins, Keith; Wheeler, Craig

    2018-01-01

    The Center for Astrophysical Plasma Properties (CAPP) is a new center focusing on the spectroscopic properties of stars and accretion disks using “at-parameter” experiments. Currently, these experiments use the X-ray output of the Z machine at Sandia National Laboratories—the largest X-ray source in the world—to heat plasmas to the same conditions (temperature, density, and radiation environment) as those observed in astronomical objects. Current experiments include measuring (1) density-dependent opacities of iron-peak elements at solar interior conditions, (2) spectral lines of low-Z elements at white dwarf photospheric conditions, (3) atomic population kinetics of neon in a radiation-dominated environment, and (4) resonant Auger destruction (RAD) of silicon at accretion disk conditions around supermassive black holes. We will be moving to new astrophysical environments and additional experimental facilities, such as the National Ignition Facility (NIF) and the OMEGA facility at the Laboratory for Laser Energetics (LLE). We seek students and collaborators to work on these experiments as well as the calculations that complement them. CAPP has funding for 5 years and can support up to six graduate students and three post-docs.

  17. Trauma Center Staffing, Infrastructure, and Patient Characteristics that Influence Trauma Center Need

    Directory of Open Access Journals (Sweden)

    Faul, Mark

    2014-11-01

    Full Text Available Introduction: The most effective use of trauma center resources helps reduce morbidity and mortality, while saving costs. Identifying critical infrastructure characteristics, patient characteristics and staffing components of a trauma center associated with the proportion of patients needing major trauma care will help planners create better systems for patient care.   Methods: We used the 2009 National Trauma Data Bank-Research Dataset to determine the proportion of critically injured patients requiring the resources of a trauma center within each Level I-IV trauma center (n=443. The outcome variable was defined as the portion of treated patients who were critically injured. We defined the need for critical trauma resources and interventions (“trauma center need” as death prior to hospital discharge, admission to the intensive care unit, or admission to the operating room from the emergency department as a result of acute traumatic injury. Generalized Linear Modeling (GLM was used to determine how hospital infrastructure, staffing Levels, and patient characteristics contributed to trauma center need.     Results: Nonprofit Level I and II trauma centers were significantly associated with higher levels of trauma center need. Trauma centers that had a higher percentage of transferred patients or a lower percentage of insured patients were associated with a higher proportion of trauma center need.  Hospital infrastructure characteristics, such as bed capacity and intensive care unit capacity, were not associated with trauma center need. A GLM for Level III and IV trauma centers showed that the number of trauma surgeons on staff was associated with trauma center need. Conclusion: Because the proportion of trauma center need is predominantly influenced by hospital type, transfer frequency, and insurance status, it is important for administrators to consider patient population characteristics of the catchment area when planning the

  18. Center Planning and Development Student Engineer

    Science.gov (United States)

    Jenkins, Kenneth T.

    2013-01-01

    This fall I was the Student Trainee (Engineering) Pathways Intern (co-op) at the Kennedy Space Center (KSC) in the Center Planning Development (CPD) Directorate. CPD works with commercial companies who are interested using KSCs unique capabilities in spaceflight, spacecraft processing, ground systems and Research Development (RD) projects that fall in line with NASAs mission and goals. CPD is divided into four (4) groups: (1) AD-A, which works on the Master Planning for center, (2) AD-B (where I am), which works on project management and integration, (3) AD-C, which works on partnership development, and (4) AD-T, which works on the RD aspects of partnerships. CPDs main goal is to one day make KSC the worlds largest spaceport and maintain the center as a leader in space exploration. CPD is a very diverse group with employees having a wide knowledge of not only the Space Shuttle, but also that of the Apollo era. Our director of CPD, Scott Colloredo, is on the advisory board for Commercial Space Operations (CSO) and has a degree at ERAU. I worked on a number of different tasks for AD-B, as well as CPD, that includes, but not limited to: reviewing and reissuing engineering drawings from the Apollo and Shuttle eras, to supporting NASA rocket launches (MAVEN), and working on actual agreementsproposals that will be used in the partnership process with multiple partners. Most of the work I have done is sensitive information and cannot be disclosed.

  19. Handbook on data centers

    CERN Document Server

    Khan, Samee Ullah

    2015-01-01

    This handbook offers a comprehensive review of the state-of-the-art research achievements in the field of data centers. Contributions from international, leading researchers and scholars offer topics in cloud computing, virtualization in data centers, energy efficient data centers, and next generation data center architecture.  It also comprises current research trends in emerging areas, such as data security, data protection management, and network resource management in data centers. Specific attention is devoted to industry needs associated with the challenges faced by data centers, such as various power, cooling, floor space, and associated environmental health and safety issues, while still working to support growth without disrupting quality of service. The contributions cut across various IT data technology domains as a single source to discuss the interdependencies that need to be supported to enable a virtualized, next-generation, energy efficient, economical, and environmentally friendly data cente...

  20. Call Center Capacity Planning

    DEFF Research Database (Denmark)

    Nielsen, Thomas Bang

    in order to relate the results to the service levels used in call centers. Furthermore, the generic nature of the approximation is demonstrated by applying it to a system incorporating a dynamic priority scheme. In the last paper Optimization of overflow policies in call centers, overflows between agent......The main topics of the thesis are theoretical and applied queueing theory within a call center setting. Call centers have in recent years become the main means of communication between customers and companies, and between citizens and public institutions. The extensively computerized infrastructure...... in modern call centers allows for a high level of customization, but also induces complicated operational processes. The size of the industry together with the complex and labor intensive nature of large call centers motivates the research carried out to understand the underlying processes. The customizable...

  1. The guiding center Lagrangian

    International Nuclear Information System (INIS)

    Larsson, J.

    1986-01-01

    Recursion relations determining the guiding center Langrangian Λ and the associated guiding center variables to all orders are derived. We consider some particularly simple forms of Λ obtainable by specific choices of certain arbitrary functions appearing as free parameters in the theory. It is, for example, possible to locally define the guiding center variables so that the expression for the corresponding Langrangian is unchanged by all higher order terms. (orig.)

  2. The efficiency of subset selection of an epsilon-best uniform population relative to selection of the best one

    NARCIS (Netherlands)

    Laan, van der P.

    1993-01-01

    Assume k (\\geq 2) uniform populations are given on (\\mu_i - ½, \\mu_i + ½) with location parameter \\mu_i \\in R^1, i = 1, ..., k. The best population is defined as the population with the largest value of the location parameter. In \\epsilon-best population (with \\epsilon \\geq 0) is a population with

  3. Environmental Modeling Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Environmental Modeling Center provides the computational tools to perform geostatistical analysis, to model ground water and atmospheric releases for comparison...

  4. Chemical Security Analysis Center

    Data.gov (United States)

    Federal Laboratory Consortium — In 2006, by Presidential Directive, DHS established the Chemical Security Analysis Center (CSAC) to identify and assess chemical threats and vulnerabilities in the...

  5. Center for Women Veterans

    Science.gov (United States)

    ... Business with VA Acquisition, Logistics, & Construction Small & Veteran Business Programs VetBiz.gov Financial & Asset Enterprise Management Security Investigation Center/Background Clearances Freedom of Information ...

  6. Small Business Development Center

    Data.gov (United States)

    Small Business Administration — Small Business Development Centers (SBDCs) provide assistance to small businesses and aspiring entrepreneurs throughout the United States and its territories. SBDCs...

  7. Center for Deployment Psychology

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Deployment Psychology was developed to promote the education of psychologists and other behavioral health specialists about issues pertaining to the...

  8. Advanced Simulation Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Simulation Center consists of 10 individual facilities which provide missile and submunition hardware-in-the-loop simulation capabilities. The following...

  9. Electron Microscopy Center (EMC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Electron Microscopy Center (EMC) at Argonne National Laboratory develops and maintains unique capabilities for electron beam characterization and applies those...

  10. Audio Visual Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Audiovisual Services Center provides still photographic documentation with laboratory support, video documentation, video editing, video duplication, photo/video...

  11. Test Control Center (TCC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Test Control Center (TCC) provides a consolidated facility for planning, coordinating, controlling, monitoring, and analyzing distributed test events. ,The TCC...

  12. Moral dilemmas faced by hospitals in time of war: the Rambam Medical Center during the second Lebanon war.

    Science.gov (United States)

    Bar-El, Yaron; Reisner, Shimon; Beyar, Rafael

    2014-02-01

    Rambam Medical Center, the only tertiary care center and largest hospital in northern Israel, was subjected to continuous rocket attacks in 2006. This extreme situation posed serious and unprecedented ethical dilemmas to the hospital management. An ambiguous situation arose that required routine patient care in a tertiary modern hospital together with implementation of emergency measures while under direct fire. The physicians responsible for hospital management at that time share some of the moral dilemmas faced, the policy they chose to follow, and offer a retrospective critical reflection in this paper. The hospital's first priority was defined as delivery of emergency surgical and medical services to the wounded from the battlefields and home front, while concomitantly providing the civilian population with all elective medical and surgical services. The need for acute medical service was even more apparent as the situation of conflict led to closure of many ambulatory clinics, while urgent or planned medical care such as open heart surgery and chemotherapy continued. The hospital management took actions to minimize risks to patients, staff, and visitors during the ongoing attacks. Wards were relocated to unused underground spaces and corridors. However due to the shortage of shielded spaces, not all wards and patients could be relocated to safer areas. Modern warfare will most likely continue to involve civilian populations and institutes, blurring the division between peaceful high-tech medicine and the rough battlefront. Hospitals in high war-risk areas must be prepared to function and deliver treatment while under fire or facing similar threats.

  13. Population crises and population cycles.

    Science.gov (United States)

    Russell, C; Russell, W M

    2000-01-01

    To prevent a population irretrievably depleting its resources, mammals have evolved a behavioural and physiological response to population crisis. When a mammalian population becomes dangerously dense, there is a reversal of behaviour. Co-operation and parental behaviour are replaced by competition, dominance and aggressive violence, leading to high mortality, especially of females and young, and a reduced population. The stress of overpopulation and the resulting violence impairs both the immune and the reproductive systems. Hence epidemics complete the crash of the population, and reproduction is slowed for three or four generations, giving the resources ample time to recover. In some mammal species, crisis and crisis response recur regularly, leading to cycles of population growth and relapse, oscillating about a fixed mean. Population crisis response and population cycles have been equally prominent in the history of human societies. But in man successive advances in food production have made possible growing populations, though with every such advance population soon outgrew resources again. Hence human cycles have been superimposed on a rising curve, producing a saw-tooth graph. Because advances in food production amounted to sudden disturbances in the relations between human populations and their environments, the crisis response in man has failed to avert famine and resource damage. In the large human societies evolved since the coming of settled agriculture and cities, the basic effects of violence, epidemics, famine and resource damage have been mediated by such specifically human disasters as inflation, unemployment, and political tyranny. An account of past crises, periods of relative relief from population pressure, and resulting cycles, is given for a number of regions: China, North Africa and Western Asia, the northern Mediterranean, and north-western Europe. The paper ends with an account of the present world-wide population crisis, and the solution

  14. Maintenance cost control at the Pacific Missile Test Center.

    OpenAIRE

    Jenson, Richard J.

    1980-01-01

    Approved for public release; distribution is unlimited The Pacific Missile Test Center (PMTC) is the Navy's largest Major Range and Test Facility Base, with an investment of over one billion dollars. The majority of this investment is in range test equipment and facilities including radar, telemetry, communication and command/ control systems. Concern is growing over the "excessively obsolete condition of PMTC technical equipment." Improvement of factors concerned with...

  15. Imaginary populations

    Directory of Open Access Journals (Sweden)

    A. Martínez–Abraín

    2010-01-01

    Full Text Available A few years ago, Camus & Lima (2002 wrote an essay to stimulate ecologists to think about how we define and use a fundamental concept in ecology: the population. They concluded, concurring with Berryman (2002, that a population is "a group of individuals of the same species that live together in an area of sufficient size to permit normal dispersal and/or migration behaviour and in which population changes are largely the results of birth and death processes". They pointed out that ecologists often forget "to acknowledge that many study units are neither natural nor even units in terms of constituting a population system", and hence claimed that we "require much more accuracy than in past decades in order to be more effective to characterize populations and predict their behaviour". They stated that this is especially necessary "in disciplines such as conservation biology or resource pest management, to avoid reaching wrong conclusions or making inappropriate decisions". As a population ecologist and conservation biologist I totally agree with these authors and, like them, I be¬lieve that greater precision and care is needed in the use and definition of ecological terms. The point I wish to stress here is that we ecologists tend to forget that when we use statistical tools to infer results from our sample to a population we work with what statisticians term "imaginary", "hypothetical" or "potential" popula¬tions. As Zar (1999 states, if our sample data consist of 40 measurements of growth rate in guinea pigs "the population about which conclusions might be drawn is the growth rates of all the guinea pigs that conceivably might have been administered the same food supplement under identical conditions". Such a population does not really exist, and hence it is considered a hypothetical or imaginary population. Compare that definition with the population concept that would be in our minds when performing such measurements. We would probably

  16. [Polytrauma in children and adolescents. Choice of the primary care clinic and importance of pediatric traumatology competence centers].

    Science.gov (United States)

    Debus, F; Lefering, R; Frink, M; Kühne, C; Mand, C; Ruchholtz, S

    2015-05-01

    The number of (seriously) injured children increased again for the first time in 2011. The aim of this study was to analyse differences compared to multiple injured adults and to show the reality of daily treatment. All cases of the DGU Trauma Registry from the years 1997 to 2010 were examined. The documented cases were divided into different the age groups. The study investigated, e.g. the mechanism of accident, injury pattern, the number of hospital and ICU days, and lethality. At 38.8% the largest percentage of severely injured children and adolescents belongs to the group of 16-17 year olds. The group of 0-5 year olds (15.9%) has the lowest percentage. The most common accident cause was traffic accidents (58.5%). The mechanism of accident and the injury patterns changes with age. Younger patients are often treated in supraregional trauma centers (0-5 year olds: 78.2% vs. 16-17 year olds: 73.1% vs. > 65 years: 63.2%). The average lethality rate was 14.8% (16.3% RISC). The percentage of severely injured children in the overall population is only 7.4%. Because the majority of patients are primarily treated in supraregional trauma centers, trauma centers with specialisation in paediatric traumatology are mandatory.

  17. Population policy.

    Science.gov (United States)

    1987-03-01

    Participants in the Seminar on Population Policies for Top-level Policy Makers and Program Managers, meeting in Thailand during January 1987, examined the challenges now facing them regarding the implementation of fertility regulation programs in their respective countries -- Bangladesh, China, India, Indonesia, Malaysia, Nepal, Pakistan, the Philippines, the Republic of Korea, and Thailand. This Seminar was organized to coincide with the completion of an Economic and Social Commission for Asia and the Pacific (ESCAP) study investigating the impact and efficiency of family planning programs in the region. Country studies were reviewed at the Seminar along with policy issues about the status of women, incentive and disincentive programs, and socioeconomic factors affecting fertility. In Bangladesh the government recognizes population growth as its top priority problem related to the socioeconomic development of the country and is working to promote a reorientation strategy from the previous clinic-oriented to a multidimensional family welfare program. China's family planning program seeks to postpone marraige, space the births of children between 3-5 years, and promote the 1-child family. Its goal is to reduce the rate of natural increase from 12/1000 in 1978 to 5/1000 by 1985 and 0 by 2000. India's 7th Five-Year-Plan (1986-90) calls for establishing a 2-child family norm by 2000. In Indonesia the government's population policy includes reducing the rate of population growth, achieving a redistribution of the population, adjusting economic factors, and creating prosperous families. The government of Indonesia reversed its policy to reduce the population growth rate in 1984 and announced its goal of achieving a population of 70 million by 2100 in order to support mass consumption industries. It has created an income tax deduction system favoring large families and maternity benefits for women who have up to 5 children as incentives. Nepal's official policy is to

  18. Naval Health Research Center 1985 Annual Report

    Science.gov (United States)

    1985-01-01

    strengthening programs for the entire crew. Aerobic programs for select populations (e.g., overweight personnel), however, were found on 20% of the...Institute, Lima Detachment, Peru (Command) 25-26 UCOR R. Kallal, CUP W. J. Lambert, & M. Nave, Naval Data Services Center, Bethesda, Maryland (Dr

  19. Africa region population projections : 1990-91

    OpenAIRE

    Stephens, Patience W.; Bos, Eduard; Vu, My T.; Bulatao, Rodolfo A.

    1991-01-01

    As recently as the mid-1970s, the Africa region had a smaller population than the Asia, the Latin American and the Caribbean, or the Europe, Middle East, and North Africa regions. Explosive population growth of more than 3 percent per year, projected to decline only gradually, will make Africa the second largest region by 2005. Its share of the world's population will increase from less than 10 percent now to 20 percent in the middle of the next century and to 25 percent when stationarity is ...

  20. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... main content Languages 简体中文 English Bahasa Indonesia 한국어 Español ภาษาไทย Tiếng Việt Text Size: Decrease Font Increase ... Monoxide Information Center Carbon Monoxide Information Center En Español The Invisible Killer Carbon monoxide, also known as ...

  1. The Revitalized Tutoring Center

    Science.gov (United States)

    Koselak, Jeremy

    2017-01-01

    One high-leverage strategy rooted in a strong research base--the revitalized tutoring center--provides a wealth of opportunity to students who may be otherwise underserved. This embedded, open-all-day tutoring center supports collaborative teacher teams by using peer tutors and community volunteers. By centralizing resources and providing supports…

  2. From Periphery To Center

    DEFF Research Database (Denmark)

    Carré, David

    2014-01-01

    the notions of Center/Periphery. As Hermans (2001) proposed, center and periphery are not fixed ‘I-positions’ of the self; in this vein, these notions are explored as relevant theoretical tools for addressing the developmental trajectories involved in the construction of scientific identities. In sum...

  3. ENERGY RESOURCES CENTER

    Energy Technology Data Exchange (ETDEWEB)

    Sternberg, Virginia

    1979-11-01

    First I will give a short history of this Center which has had three names and three moves (and one more in the offing) in three years. Then I will tell you about the accomplishments made in the past year. And last, I will discuss what has been learned and what is planned for the future. The Energy and Environment Information Center (EEIC), as it was first known, was organized in August 1975 in San Francisco as a cooperative venture by the Federal Energy Administration (FEA), Energy Research and Development Administration (ERDA) and the Environmental Protection Agency (EPA). These three agencies planned this effort to assist the public in obtaining information about energy and the environmental aspects of energy. The Public Affairs Offices of FEA, ERDA and EPA initiated the idea of the Center. One member from each agency worked at the Center, with assistance from the Lawrence Berkeley Laboratory Information Research Group (LBL IRG) and with on-site help from the EPA Library. The Center was set up in a corner of the EPA Library. FEA and ERDA each contributed one staff member on a rotating basis to cover the daily operation of the Center and money for books and periodicals. EPA contributed space, staff time for ordering, processing and indexing publications, and additional money for acquisitions. The LBL Information Research Group received funds from ERDA on a 189 FY 1976 research project to assist in the development of the Center as a model for future energy centers.

  4. Accredited Birth Centers

    Science.gov (United States)

    ... Danbury, CT 06810 203-748-6000 Accredited Since March 1998 Corvallis Birth & Women's Health Center Accredited 2314 NW Kings Blvd, Suite ... Washington, DC 20002 202-398-5520 Accredited Since March 2001 Flagstaff Birth and Women's Center Accredited 401 West Aspen Avenue Flagstaff, AZ ...

  5. Technology Information Center

    International Nuclear Information System (INIS)

    Emerson, E.L.; Shepherd, E.W.; Minor, E.E.

    1980-01-01

    A Transportation Technology Center (TTC) has been established at Sandia to address the transportation of nuclear waste and spent fuel. The Technology Information Center (TIC) acts as TTC's clearing house for nuclear material transportation information. TIC's activities are divided into three activities: public information, policy information, and technical information. Some of the uses of TIC's activities are briefly outlined

  6. Funding Opportunity: Genomic Data Centers

    Science.gov (United States)

    Funding Opportunity CCG, Funding Opportunity Center for Cancer Genomics, CCG, Center for Cancer Genomics, CCG RFA, Center for cancer genomics rfa, genomic data analysis network, genomic data analysis network centers,

  7. IMAA (Integrated Measurements of Aerosol in Agri valley) campaign: Multi-instrumental observations at the largest European oil/gas pre-treatment plant area

    Science.gov (United States)

    Calvello, Mariarosaria; Caggiano, Rosa; Esposito, Francesco; Lettino, Antonio; Sabia, Serena; Summa, Vito; Pavese, Giulia

    2017-11-01

    A short-term intensive multi-instrumental measurement campaign (Integrated Measurements of Aerosol in Agri valley - IMAA) was carried out near the largest European oil and gas pre-treatment plant (Centro Olio Val d'Agri - COVA) in a populated area, where, so far, ample characterization of aerosol loading is missing. As such, between the 2 and 17 July in 2013, using a number of instruments analyses were carried out on physical, chemical, morphological and optical properties of aerosol at this distinctive site, at both ground and over the atmospheric column, including the investigation of the mixing and transformation of particles. The observation of slag silicates with a rough surface texture is consistent with the presence of oil-related activities which represent the only industrial activity in the area. Desulfurization/sulfur liquefaction processes occurring at COVA can explain the peculiar morphology of calcium-sodium-aluminum particles. The common COVA source was associated with high concentrations of sulfur, nickel and zinc, and with significant correlations between zinc-sulfur and zinc-nickel. The Optical Particle Sizer (OPS) data, hygroscopicity and optical properties of atmospheric aerosol are consistent with the typical oil-derived gaseous emissions (e.g. sulfur dioxide and methane) that strongly influence the mixing state of particles and their size distributions. Continuous combustion processes at COVA were found to be responsible for Equivalent Black Carbon (EBC) concentrations from their relevant contribution to the total number of fine particles. The expected significant contribution of WS (water soluble) and BC (Black Carbon) components to the total Aerosol Optical Depth (AOD) are consistent with the results from the radiometric model especially for July 3 and 16.

  8. Long-term outcomes after allogeneic hematopoietic stem cell transplantation for metachromatic leukodystrophy: the largest single-institution cohort report

    OpenAIRE

    Boucher, Alexander A.; Miller, Weston; Shanley, Ryan; Ziegler, Richard; Lund, Troy; Raymond, Gerald; Orchard, Paul J.

    2015-01-01

    Background Metachromatic Leukodystrophy (MLD) is a rare, fatal demyelinating disorder with limited treatment options. Published outcomes after hematopoietic stem cell transplantation (HSCT) are scant and mixed. We report survival and function following HSCT for a large, single-center MLD cohort. Methods Transplant-related data, survival and serial measures (brain MRI, nerve conduction velocity (NCV), neurologic and neuropsychology evaluations) were reviewed. When possible, parental interviews...

  9. Relative Lyapunov Center Bifurcations

    DEFF Research Database (Denmark)

    Wulff, Claudia; Schilder, Frank

    2014-01-01

    Relative equilibria (REs) and relative periodic orbits (RPOs) are ubiquitous in symmetric Hamiltonian systems and occur, for example, in celestial mechanics, molecular dynamics, and rigid body motion. REs are equilibria, and RPOs are periodic orbits of the symmetry reduced system. Relative Lyapunov...... center bifurcations are bifurcations of RPOs from REs corresponding to Lyapunov center bifurcations of the symmetry reduced dynamics. In this paper we first prove a relative Lyapunov center theorem by combining recent results on the persistence of RPOs in Hamiltonian systems with a symmetric Lyapunov...... center theorem of Montaldi, Roberts, and Stewart. We then develop numerical methods for the detection of relative Lyapunov center bifurcations along branches of RPOs and for their computation. We apply our methods to Lagrangian REs of the N-body problem....

  10. Population structure in Argentina.

    Directory of Open Access Journals (Sweden)

    Marina Muzzio

    Full Text Available We analyzed 391 samples from 12 Argentinian populations from the Center-West, East and North-West regions with the Illumina Human Exome Beadchip v1.0 (HumanExome-12v1-A. We did Principal Components analysis to infer patterns of populational divergence and migrations. We identified proportions and patterns of European, African and Native American ancestry and found a correlation between distance to Buenos Aires and proportion of Native American ancestry, where the highest proportion corresponds to the Northernmost populations, which is also the furthest from the Argentinian capital. Most of the European sources are from a South European origin, matching historical records, and we see two different Native American components, one that spreads all over Argentina and another specifically Andean. The highest percentages of African ancestry were in the Center West of Argentina, where the old trade routes took the slaves from Buenos Aires to Chile and Peru. Subcontinentaly, sources of this African component are represented by both West Africa and groups influenced by the Bantu expansion, the second slightly higher than the first, unlike North America and the Caribbean, where the main source is West Africa. This is reasonable, considering that a large proportion of the ships arriving at the Southern Hemisphere came from Mozambique, Loango and Angola.

  11. An estimation of the capacity to produce hydrogen by wasted hydroelectric energy for the three largest Brazilian hydroelectric

    Energy Technology Data Exchange (ETDEWEB)

    Padilha, Janine C.; Trindade, Leticia G. da; Souza, Roberto F. de [Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS (Brazil). Inst. of Chemistry], Email: janine@iq.ufrgs.br; Miguel, Marcelo [Itaipu Binacional, Foz do Iguacu, PR (Brazil)

    2010-07-01

    The use of water wasted in hydroelectric plants as normalization dam excess, which constitute a hydrodynamic potential useful to generate electric energy which can be subsequently used to produce hydrogen and its subsequent consumption in fuel cells has been considered as an alternative for hydraulic energy-rich countries like Brazil. The case is examined in which all the water wasted in the hydroelectric plants, spilled by dam gates to maintain acceptable water levels, from the 3 largest Brazilian hydroelectric plants was used to produce hydrogen. During the year of 2008, the electric energy produced from this utilization would have been equivalent to 52.8 TWh, an amount that corresponds to an increase of ca. 15% of the total electric energy produced in the country. Furthermore, if this amount of hydrogen was used in the replacement of internal combustion vehicles by fuel cells, this would have prevented the production of 2.26 x 10{sup 7} ton of Co{sub 2} per year. This plan would also significantly decrease production and release of greenhouse gases. (author)

  12. Community structure and decadal changes in macrozoobenthic assemblages in Lake Poyang, the largest freshwater lake in China

    Directory of Open Access Journals (Sweden)

    Cai Y. J.

    2014-01-01

    Full Text Available Lake Poyang is the largest freshwater lake in China and contains unique and diverse biota within the Yangtze floodplain ecosystem. However, knowledge of its macrozoobenthic assemblages remains inadequate. To characterize the current community structure of these assemblages and to portray their decadal changes, quarterly investigations were conducted at 15 sites from February to November 2012. A total of 42 taxa were recorded, and Corbicula fluminea, Limnoperna fortunei, Gammaridae sp., Nephtys polybranchia, Polypedilum scalaenum and Branchiura sowerbyi were found to dominate the community in terms of abundance. The bivalves Corbicula fluminea, Lamprotula rochechouarti, Arconaia lanceolata and Lamprotula caveata dominated the community in biomass due to their large body size. The mean abundance of the total macrozoobenthos varied from 48 to 920 ind·m-2, the mean biomass ranged from 28 to 428 g·m-2. The substrate type affected strongly the abundance, biomass, and diversity of the macrozoobenthos, with muddy sand substrates showing the highest values. Compared with historical data, remarkable changes were observed in the abundance of macrozoobenthos and the identity of the dominant species. The mean total abundance decreased from 724 ind·m-2 in 1992 to 228 ind·m-2 in 2012. The dominant species have shifted dramatically. Large unionids were dominant before 1998, whereas pollution-tolerant species (e.g., Branchiura sowerbyi increased in dominance after 2008. Our findings should have implications for the conservation of the benthic biodiversity of this large Yangtze-connected lake.

  13. Properties of the probability distribution associated with the largest event in an earthquake cluster and their implications to foreshocks

    International Nuclear Information System (INIS)

    Zhuang Jiancang; Ogata, Yosihiko

    2006-01-01

    The space-time epidemic-type aftershock sequence model is a stochastic branching process in which earthquake activity is classified into background and clustering components and each earthquake triggers other earthquakes independently according to certain rules. This paper gives the probability distributions associated with the largest event in a cluster and their properties for all three cases when the process is subcritical, critical, and supercritical. One of the direct uses of these probability distributions is to evaluate the probability of an earthquake to be a foreshock, and magnitude distributions of foreshocks and nonforeshock earthquakes. To verify these theoretical results, the Japan Meteorological Agency earthquake catalog is analyzed. The proportion of events that have 1 or more larger descendants in total events is found to be as high as about 15%. When the differences between background events and triggered event in the behavior of triggering children are considered, a background event has a probability about 8% to be a foreshock. This probability decreases when the magnitude of the background event increases. These results, obtained from a complicated clustering model, where the characteristics of background events and triggered events are different, are consistent with the results obtained in [Ogata et al., Geophys. J. Int. 127, 17 (1996)] by using the conventional single-linked cluster declustering method

  14. Properties of the probability distribution associated with the largest event in an earthquake cluster and their implications to foreshocks.

    Science.gov (United States)

    Zhuang, Jiancang; Ogata, Yosihiko

    2006-04-01

    The space-time epidemic-type aftershock sequence model is a stochastic branching process in which earthquake activity is classified into background and clustering components and each earthquake triggers other earthquakes independently according to certain rules. This paper gives the probability distributions associated with the largest event in a cluster and their properties for all three cases when the process is subcritical, critical, and supercritical. One of the direct uses of these probability distributions is to evaluate the probability of an earthquake to be a foreshock, and magnitude distributions of foreshocks and nonforeshock earthquakes. To verify these theoretical results, the Japan Meteorological Agency earthquake catalog is analyzed. The proportion of events that have 1 or more larger descendants in total events is found to be as high as about 15%. When the differences between background events and triggered event in the behavior of triggering children are considered, a background event has a probability about 8% to be a foreshock. This probability decreases when the magnitude of the background event increases. These results, obtained from a complicated clustering model, where the characteristics of background events and triggered events are different, are consistent with the results obtained in [Ogata, Geophys. J. Int. 127, 17 (1996)] by using the conventional single-linked cluster declustering method.

  15. Customized overhead cranes for installation of India's largest 3.6m optical telescope at Devasthal, Nainital, India

    Science.gov (United States)

    Bangia, Tarun; Yadava, Shobhit; Kumar, Brijesh; Ghanti, A. S.; Hardikar, P. M.

    2016-07-01

    India's largest 3.6 m aperture optical telescope facility has been recently established at Devasthal site by Aryabhatta Research Institute of Observation Sciences (ARIES), an autonomous Institute under Department of Science and Technology, Government of India. The telescope is equipped with active optics and it is designed to be used for seeinglimited observations at visible and near-infrared wavelengths. A steel building with rotating cylindrical steel Dome was erected to house 3.6m telescope and its accessories at hilltop of Devasthal site. Customized cranes were essentially required inside the building as there were space constraints around the telescope building for operating big external heavy duty cranes from outside, transportation constraints in route for bringing heavy weight cranes, altitude of observatory, and sharp bends etc. to site. To meet the challenge of telescope installation from inside the telescope building by lifting components through its hatch, two Single Girder cranes and two Under Slung cranes of 10 MT capacity each were specifically designed and developed. All the four overhead cranes were custom built to achieve the goal of handling telescope mirror and its various components during installation and assembly. Overhead cranes were installed in limited available space inside the building and tested as per IS 3177. Cranes were equipped with many features like VVVFD compatibility, provision for tandem operation, digital load display, anti-collision mechanism, electrical interlocks, radio remote, low hook height and compact carriage etc. for telescope integration at site.

  16. Significant human impact on the flux and δ(34)S of sulfate from the largest river in North America.

    Science.gov (United States)

    Killingsworth, Bryan A; Bao, Huiming

    2015-04-21

    Riverine dissolved sulfate (SO4(2-)) flux and sulfur stable isotope composition (δ(34)S) yield information on the sources and processes affecting sulfur cycling on different spatial and temporal scales. However, because pristine preindustrial natural baselines of riverine SO4(2-) flux and δ(34)S cannot be directly measured, anthropogenic impact remains largely unconstrained. Here we quantify natural and anthropogenic SO4(2-) flux and δ(34)S for North America's largest river, the Mississippi, by means of an exhaustive source compilation and multiyear monitoring. Our data and analysis show that, since before industrialization to the present, Mississippi River SO4(2-) has increased in flux from 7.0 to 27.8 Tg SO4(2-) yr(-1), and in mean δ(34)S from -5.0‰, within 95% confidence limits of -14.8‰ to 4.1‰ (assuming normal distribution for mixing model input parameters), to -2.7 ± 1.6‰, reflecting an impressive footprint of bedrocks particular to this river basin and human activities. Our first-order modern Mississippi River sulfate partition is 25 ± 6% natural and 75% ± 6% anthropogenic sources. Furthermore, anthropogenic coal usage is implicated as the dominant source of modern Mississippi River sulfate, with an estimated 47 ± 5% and 13% of total Mississippi River sulfate due to coal mining and burning, respectively.

  17. Atmospheric thorium pollution and inhalation exposure in the largest rare earth mining and smelting area in China.

    Science.gov (United States)

    Wang, Lingqing; Zhong, Buqing; Liang, Tao; Xing, Baoshan; Zhu, Yifang

    2016-12-01

    Exposure to radionuclide thorium (Th) has generated widespread public concerns, mainly because of its radiological effects on human health. Activity levels of airborne 232 Th in total suspended particulate (TSP) were measured in the vicinity of the largest rare earth mine in China in August 2012 and March 2013. The mean activity concentrations of 232 Th in TSP ranged from 820μBqm -3 in a mining area in August 2012 to 39,720μBqm -3 in a smelting area in March 2013, much higher than the world reference of 0.5μBqm -3 . Multistatistical analysis and Kohonen's self-organizing maps suggested that 232 Th in TSP was mainly derived from rare earth mining and smelting practices. In addition, personal inhalation exposures to 232 Th associated with respirable particulate (PM 10 ) were also measured among local dwellers via personal monitoring. The mean dose values for different age groups in the smelting and mining areas ranged from 97.86 to 417μSvyear - 1 and from 101.03 to 430.83μSvyear -1 , respectively. These results indicate that people living in the study areas are exposed to high levels of widespread 232 Th. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Injury Rates on New and Old Technology Oil and Gas Rigs Operated by the Largest United States Onshore Drilling Contractor

    Science.gov (United States)

    Blackley, David J.; Retzer, Kyla D.; Hubler, Warren G.; Hill, Ryan D.; Laney, A. Scott

    2015-01-01

    Background Occupational fatality rates among oil and gas extraction industry and specifically among drilling contractor workers are high compared to the U.S. all-industry average. There is scant literature focused on non-fatal injuries among drilling contractors, some of which have introduced engineering controls to improve rig efficiency and reduce injury risk. Methods We compared injury rates on new and old technology rigs operated by the largest U.S. drilling contractor during 2003–2012, stratifying by job type and grouping outcomes by injury severity and body part affected. Results Six hundred seventy-one injuries were recorded over 77.4 million person-hours. The rate on new rigs was 66% of that on old rigs. Roughnecks had lower injury rates on new rigs, largely through reduced limb injury rates. New rigs had lower rates in each non-fatal injury severity category. Conclusions For this company, new technology rigs appear to provide a safer environment for roughnecks. Future studies could include data from additional companies. PMID:25164118

  19. BEHAVIOR OF THE TEN LARGEST BRAZILIAN BANKS DURING THE SUBPRIME CRISIS: AN ANALYSIS BASED ON FINANCIAL INDICATORS

    Directory of Open Access Journals (Sweden)

    Rosane Maria Pio da Silva

    2012-06-01

    Full Text Available The aim of this paper is to demonstrate the behavior of the ten largest Brazilian banks between June 2008 and September 2009, based on the analysis of financial indicators. Therefore, 16 three-monthly indices were calculated, extracted from financial statement information, which characterizes a documentary research. The indices were separated in five categories: liquidity, capital, profitability, income and market. The obtained results appointed that most financial institutions in the sample were able to manage their resources so as to gain conditions to maintain credit initially. Then, as from the first term of 2009, driven by public banks, they increased their credit operations. In addition, most banks revealed an anti-cyclical trend to encourage productive activities, preferably activities with higher liquidity levels, to the detriment of profitability, which reveals a more conservative attitude. Finally, it was verified that government initiatives, the Brazilian economic balance and the resources the banks offered helped to produce an environment to reactivate business activities during the most acute period of the subprime crisis.

  20. A look at one of the world`s largest apron feeder drives - Alberta Oil Sands Project

    Energy Technology Data Exchange (ETDEWEB)

    Persson, O. [Hagglunds Drives Canada Inc., Vancouver, BC (Canada)

    1999-10-01

    Various types of equipment to transport tar sands to processing plants are discussed, with special attention to the advantages of hydraulic direct drives over conventional electro-mechanical drives. A hydraulic direct drive such as the Hagglund Drive has exceptional starting torque capacity due to the high torque capability of the hydraulic motor. As such, it can be particularly useful in applications where shock loads occur with some frequency, or where many starts and stops are needed. Application of the Hagglund drive to power one of the world`s largest apron feeders in the Alberta Oil Sands is described as an illustration of the exceptional reliability, productivity and performance of this equipment. It has about one five-hundredth of the inertia of an equivalent high speed drive with gear reducer, a feature which is particularly significant in the case of feeders which are known to suffer much downtime due to chain related problems. These types of drives have also been used to great advantage in the process industries like pulp and paper, chemical, rubber and plastics, recycling and steel. 1 tab., 1 fig.

  1. A look at one of the world's largest apron feeder drives - Alberta Oil Sands Project

    Energy Technology Data Exchange (ETDEWEB)

    Persson, O. (Hagglunds Drives Canada Inc., Vancouver, BC (Canada))

    1999-01-01

    Various types of equipment to transport tar sands to processing plants are discussed, with special attention to the advantages of hydraulic direct drives over conventional electro-mechanical drives. A hydraulic direct drive such as the Hagglund Drive has exceptional starting torque capacity due to the high torque capability of the hydraulic motor. As such, it can be particularly useful in applications where shock loads occur with some frequency, or where many starts and stops are needed. Application of the Hagglund drive to power one of the world's largest apron feeders in the Alberta Oil Sands is described as an illustration of the exceptional reliability, productivity and performance of this equipment. It has about one five-hundredth of the inertia of an equivalent high speed drive with gear reducer, a feature which is particularly significant in the case of feeders which are known to suffer much downtime due to chain related problems. These types of drives have also been used to great advantage in the process industries like pulp and paper, chemical, rubber and plastics, recycling and steel. 1 tab., 1 fig.

  2. Swimming strategy and body plan of the world’s largest fish: implications for foraging efficiency and thermoregulation

    Directory of Open Access Journals (Sweden)

    Mark eMeekan

    2015-09-01

    Full Text Available The largest animals in the oceans eat prey that are orders of magnitude smaller than themselves, implying strong selection for cost-effective foraging to meet their energy demands. Whale sharks (Rhincodon typus may be especially challenged by warm seas that elevate their metabolism and contain sparse prey resources. Using a combination of biologging and satellite tagging, we show that whale sharks use four strategies to save energy and improve foraging efficiency: 1 fixed, low power swimming, 2 constant low speed swimming, 3 gliding and 4 asymmetrical diving. These strategies increase foraging efficiency by 22 – 32% relative to swimming horizontally and resolve the energy-budget paradox of whale sharks. However, sharks in the open ocean must access food resources that reside in relatively cold waters (up to 20oC cooler than the surface at depths of 250-500 m during the daytime, where long, slow gliding descents, continuous ram ventilation of the gills and filter-feeding could rapidly cool the circulating blood and body tissues. We suggest that whale sharks may overcome this problem through their large size and a specialized body plan that isolates highly vascularized red muscle on the dorsal surface, allowing heat to be retained near the centre of the body within a massive core of white muscle. This could allow a warm-adapted species to maintain enhanced function of organs and sensory systems while exploiting food resources in deep, cool water.

  3. Largest global shark biomass found in the northern Galápagos Islands of Darwin and Wolf

    Directory of Open Access Journals (Sweden)

    Pelayo Salinas de León

    2016-05-01

    Full Text Available Overfishing has dramatically depleted sharks and other large predatory fishes worldwide except for a few remote and/or well-protected areas. The islands of Darwin and Wolf in the far north of the Galapagos Marine Reserve (GMR are known for their large shark abundance, making them a global scuba diving and conservation hotspot. Here we report quantitative estimates of fish abundance at Darwin and Wolf over two consecutive years using stereo-video surveys, which reveal the largest reef fish biomass ever reported (17.5 t ${\\mathrm{ha}}^{-1}$ ha − 1 on average, consisting largely of sharks. Despite this, the abundance of reef fishes around the GMR, such as groupers, has been severely reduced because of unsustainable fishing practices. Although Darwin and Wolf are within the GMR, they were not fully protected from fishing until March 2016. Given the ecological value and the economic importance of Darwin and Wolf for the dive tourism industry, the current protection should ensure the long-term conservation of this hotspot of unique global value.

  4. Transit profiles: The thirty largest agencies for the 1990 Section 15 report year. Rept. for Jan-Dec 90

    International Nuclear Information System (INIS)

    Futrell, M.; Black, T.N.

    1991-11-01

    The report summarizes the financial and operating data submitted to the Urban Mass Transportation Administration (UMTA) by the nation's public transit operators, pursuant to Section 15 of the Urban Mass Transportation (UMT) Act of 1964, as amended. These data represent a portion of the 1990 Annual Report and consist of transit profiles for the 30 largest agencies based on operating expenses for the 1990 report year. Each profile consists of data reporting general, summary, modal, performance and trend indicators about a particular transit system for the 1990 report year. The unaggregated data can be found in the 1990 Section 15 Annual Report Data Tables, for the 1990 Section 15 Report Year. Rather than requiring the user to assemble data from numerous tables, the Transit Profile provides the user with a comprehensive overview in graphic and summary format of an individual transit agency's financial and operating statistics for the 1990 Section 15 report year with summaries of key data items for prior years. All data in the report are for transit system fiscal years ending on or between January 1 and December 31, 1990

  5. Assimilation of remote sensing observations into a sediment transport model of China's largest freshwater lake: spatial and temporal effects.

    Science.gov (United States)

    Zhang, Peng; Chen, Xiaoling; Lu, Jianzhong; Zhang, Wei

    2015-12-01

    Numerical models are important tools that are used in studies of sediment dynamics in inland and coastal waters, and these models can now benefit from the use of integrated remote sensing observations. This study explores a scheme for assimilating remotely sensed suspended sediment (from charge-coupled device (CCD) images obtained from the Huanjing (HJ) satellite) into a two-dimensional sediment transport model of Poyang Lake, the largest freshwater lake in China. Optimal interpolation is used as the assimilation method, and model predictions are obtained by combining four remote sensing images. The parameters for optimal interpolation are determined through a series of assimilation experiments evaluating the sediment predictions based on field measurements. The model with assimilation of remotely sensed sediment reduces the root-mean-square error of the predicted sediment concentrations by 39.4% relative to the model without assimilation, demonstrating the effectiveness of the assimilation scheme. The spatial effect of assimilation is explored by comparing model predictions with remotely sensed sediment, revealing that the model with assimilation generates reasonable spatial distribution patterns of suspended sediment. The temporal effect of assimilation on the model's predictive capabilities varies spatially, with an average temporal effect of approximately 10.8 days. The current velocities which dominate the rate and direction of sediment transport most likely result in spatial differences in the temporal effect of assimilation on model predictions.

  6. A case of multiple metastatic malignant melanoma with the largest lesion in the ileum and no skin lesion

    Directory of Open Access Journals (Sweden)

    Shuji Suzuki

    2012-12-01

    Full Text Available We report the case of a 72-year-old woman with malignant melanoma and multiple metastases; the largest tumor was in the ileum. The patient experienced general fatigue and bloody feces for 1 month before consulting a nearby clinic. Blood tests revealed anemia, and fecal occult blood was positive, but no abnormalities were detected using gastrointestinal endoscopy and colonoscopy or the skin of the entire body. Computed tomography images of the chest, abdomen, and pelvic region, and positron emission tomography–computed tomography images of the entire body revealed multiple nodules in the ileum, left mammary gland, left thyroid, right inguinal lymph node, and on the fascia of the right thoracic area and right buttocks. The tumor in the left mammary gland was excised and immunohistochemical analysis revealed that the excised tissue was positive for HMB45, melan-A, and MITF, but negative for S-100 protein. Diagnosed with melanoma with multiple metastases, the patient underwent four cycles of dacarbazine, nimustine hydrochloride, and vincristine (DAV plus interferon beta chemotherapy and one cycle of dacarbazine, nimustine hydrochloride, cisplatin, and tamoxifen (DAC-Tam chemotherapy. Two series of embolizations of the artery feeding the ileum tumors, as well as a series of plasma and red blood cell transfusions, were performed for ileum tumor hemorrhage. The patient was hospitalized eight times, for a total of 204 days during the 1-year survival period before her death from respiratory failure.

  7. Injury rates on new and old technology oil and gas rigs operated by the largest United States onshore drilling contractor.

    Science.gov (United States)

    Blackley, David J; Retzer, Kyla D; Hubler, Warren G; Hill, Ryan D; Laney, A Scott

    2014-10-01

    Occupational fatality rates among oil and gas extraction industry and specifically among drilling contractor workers are high compared to the U.S. all-industry average. There is scant literature focused on non-fatal injuries among drilling contractors, some of which have introduced engineering controls to improve rig efficiency and reduce injury risk. We compared injury rates on new and old technology rigs operated by the largest U.S. drilling contractor during 2003-2012, stratifying by job type and grouping outcomes by injury severity and body part affected. Six hundred seventy-one injuries were recorded over 77.4 million person-hours. The rate on new rigs was 66% of that on old rigs. Roughnecks had lower injury rates on new rigs, largely through reduced limb injury rates. New rigs had lower rates in each non-fatal injury severity category. For this company, new technology rigs appear to provide a safer environment for roughnecks. Future studies could include data from additional companies. © 2014 Wiley Periodicals, Inc.

  8. Setting-up a cost recovery system for the largest wastewater treatment plant in South-East Asia.

    Science.gov (United States)

    Lønholdt, J; Elberg Jørgensen, P; O'Hearn, D

    2005-01-01

    A tariff system has been set up for the largest wastewater treatment plant in South-East Asia, the Samut Prakarn Wastewater Treatment Plant south of Bangkok, which is currently under completion. Fully functional the plant will have a design capacity for 500,000 m3 per day and will service a combined residential and industrial area with approximately 600,000 residents and 2,300 factories. The tariff system, which includes a tariff model, is based on water consumption and BOD load. As background for setting the tariffs a comprehensive monitoring system including an industrial permitting system has been developed. The paper presents the background and rationale for setting up the system as well as the objective, scope and content of the tariff system and the industrial permit system. Further, the feasibility of introducing cost recovery systems, which is widely accepted in developing economies on the conceptual level and to some extent implemented at the legal and regulatory level, but has yet to be implemented at large, is discussed.

  9. HIV risks and HIV prevention among female sex workers in two largest urban settings in Croatia, 2008-2014.

    Science.gov (United States)

    Štulhofer, Aleksandar; Landripet, Ivan; Božić, Jasmina; Božičević, Ivana

    2015-01-01

    Harm reduction-based HIV prevention has been in place among female sex workers (FSWs) in Croatia for more than a decade. However, little is known about how well the existing programs meet the needs of FSWs in an environment where sex work remains criminalized and highly stigmatized. This study aims to assess changes in FSWs' vulnerability to HIV infection in the 2008-2014 period. Using convenience samples of FSWs in Croatia's two largest urban settings, behavioral data were collected in 2007-2008 and 2014. Outreach workers interviewed 154 FSWs in the first wave of the survey and 158 in the second. The period under observation was characterized by a stable prevalence of most HIV-relevant risk behaviors and experiences. Significant changes in client-based victimization and HIV knowledge were observed only among FSWs in the capital city. Substantial and mostly sustained levels of sexual and nonsexual victimization call for more research into the limits of the current behavior-based harm reduction approach to HIV prevention in the country.

  10. Dispersal syndromes in the largest protection area of the Atlantic Forest in the state of Paraiba, Brazil

    Directory of Open Access Journals (Sweden)

    Camila Ângelo Jerônimo Domingues

    2013-09-01

    Full Text Available The diaspore dispersal process is crucial for plant reproduction, since the diaspores must reach a suitable site to germinate. This paper aimed to study morphological aspects of diaspores and determine the dispersal syndromes of species occurring in the largest protection area of the Atlantic Forest in the state of Paraiba, Brazil, the Guaribas Biological Reserve. One conducted a monthly collection of fruits/seeds within the period from September 2007 to February 2009. All diaspores of the fruiting species were collected. After analyzing characteristics such as fruit and seed consistency, odor, color, size, and weight, one determined the dispersal syndrome of each species. One collected 3,080 diaspores belonging to 136 different species distributed into 27 families. Zoochory was the most abundant dispersal syndrome (58%, with 79 fruits adapted to it, followed by autochory (29%, and anemochory (13%. Throughout the study period, one found fruiting species, with a predominance of zoochoric fruits, a predictable fact in the Atlantic Forest, which provides fleshy fruits all the year round.

  11. Energy efficient data centers

    Energy Technology Data Exchange (ETDEWEB)

    Tschudi, William; Xu, Tengfang; Sartor, Dale; Koomey, Jon; Nordman, Bruce; Sezgen, Osman

    2004-03-30

    Data Center facilities, prevalent in many industries and institutions are essential to California's economy. Energy intensive data centers are crucial to California's industries, and many other institutions (such as universities) in the state, and they play an important role in the constantly evolving communications industry. To better understand the impact of the energy requirements and energy efficiency improvement potential in these facilities, the California Energy Commission's PIER Industrial Program initiated this project with two primary focus areas: First, to characterize current data center electricity use; and secondly, to develop a research ''roadmap'' defining and prioritizing possible future public interest research and deployment efforts that would improve energy efficiency. Although there are many opinions concerning the energy intensity of data centers and the aggregate effect on California's electrical power systems, there is very little publicly available information. Through this project, actual energy consumption at its end use was measured in a number of data centers. This benchmark data was documented in case study reports, along with site-specific energy efficiency recommendations. Additionally, other data center energy benchmarks were obtained through synergistic projects, prior PG&E studies, and industry contacts. In total, energy benchmarks for sixteen data centers were obtained. For this project, a broad definition of ''data center'' was adopted which included internet hosting, corporate, institutional, governmental, educational and other miscellaneous data centers. Typically these facilities require specialized infrastructure to provide high quality power and cooling for IT equipment. All of these data center types were considered in the development of an estimate of the total power consumption in California. Finally, a research ''roadmap'' was developed

  12. Radiation exposure of the UK population

    International Nuclear Information System (INIS)

    Taylor, F.E.; Webb, G.A.M.

    1978-11-01

    Man is continuously exposed to radiation from many sources, both natural and man-made. The man-made sources include medical irradiation, exposure from radioactive waste disposal, fallout from nuclear weapons tests and various 'miscellaneous sources' which include consumer products. The National Radiological Protection Board (NRPB) keeps these contributions to the radiation exposure of the population under continuous review and publishes reports on the subject periodically. This is the second such report and contains considerably more information than the first published in 1974. The balance of the report reflects the availability of data and the advice given in the sixth report of the Royal Commission on Environmental Pollution. The conclusions are: (a) that the major contribution to the dose to the population is from natural background radiation; (b) that the largest man-made contribution is from medical uses of radiation; (c) that the largest contribution from environmental contamination is still from the residual effects of fallout from nuclear weapons testing; (d) that occupational exposure and irradiation from miscellaneous sources, considered as contributions to the per caput dose to the population, are the next largest components; (e) that radioactive waste disposal is the smallest contributor to the per caput dose to the population. It was also felt useful to review the past trends in the doses resulting from the various sources and the authors have attempted to make some tentative predictions of doses up to the year 2000. (author)

  13. Information sharing guidebook for transportation management centers, emergency operations centers, and fusion centers

    Science.gov (United States)

    2010-06-01

    This guidebook provides an overview of the mission and functions of transportation management centers, emergency operations centers, and fusion centers. The guidebook focuses on the types of information these centers produce and manage and how the sh...

  14. Information sharing guidebook for transportation management centers, emergency operations centers, and fusion centers.

    Science.gov (United States)

    2010-06-01

    This guidebook provides an overview of the mission and functions of transportation management centers, emergency operations centers, and fusion centers. The guidebook focuses on the types of information these centers produce and manage and how the sh...

  15. User-centered design

    International Nuclear Information System (INIS)

    Baik, Joo Hyun; Kim, Hyeong Heon

    2008-01-01

    The simplification philosophy, as an example, that both of EPRI-URD and EUR emphasize is treated mostly for the cost reduction of the nuclear power plants, but not for the simplification of the structure of user's tasks, which is one of the principles of user-centered design. A user-centered design is a philosophy based on the needs and interests of the user, with an emphasis on making products usable and understandable. However, the nuclear power plants offered these days by which the predominant reactor vendors are hardly user-centered but still designer-centered or technology-centered in viewpoint of fulfilling user requirements. The main goal of user-centered design is that user requirements are elicited correctly, reflected properly into the system requirements, and verified thoroughly by the tests. Starting from the user requirements throughout to the final test, each requirement should be traceable. That's why requirement traceability is a key to the user-centered design, and main theme of a requirement management program, which is suggested to be added into EPRI-URD and EUR in the section of Design Process. (author)

  16. What are the economic and social effects from the electric power beneficiary price of the largest consumers

    International Nuclear Information System (INIS)

    Bogov, Dimitar

    2003-01-01

    In the last few years the two largest consumers of electricity 'Feni' and 'Jugohrom', were sold to the foreign strategic investor. The key issue in the negotiations with the investor was the price of electricity for these companies. The final outcome is known, they got beneficiary price. Now two questions emerge: (1) what is the exact size of the under pricing? (2) what are the economic and social effects of their activity and whether the social gain for the country is higher than the loss for the country from the under pricing of electricity. The paper is trying to give an answer on the second question. Therewith, the analyze is focused on two issues: (1) how much is the contribution of these two companies on production, export and economic growth of the Republic of Macedonia; (2) what is their impact on the living standard and social costs. Macedonian industry has very unfavorable structure with only a few export products. Restructuring of industry and widening of the array of products is a slow process. Until new products and new industries are developed, the only generator of larger export and higher economic growth is the increase of the export of existing products. 'Feni industry' and 'Silmak' are some of rare Macedonian companies that have foreign strategic investor who provide stable and unlimited market (having in mind that Macedonian production is relatively small compared to the world demand for nickel and ferro silicium). Thus, the growth of export of metals produced by 'Feni industry' and 'Silmak' could be the principal generators of the growth of Macedonian economy in the period of restructuring of the industry and development of new competitive products. (Original)

  17. Influence of long-range transboundary transport on atmospheric water vapor mercury collected at the largest city of Tibet

    International Nuclear Information System (INIS)

    Huang, Jie; Kang, Shichang; Tian, Lide; Guo, Junming; Zhang, Qianggong; Cong, Zhiyuan; Sillanpää, Mika

    2016-01-01

    Monsoon circulation is an important process that affects long-range transboundary transport of anthropogenic contaminants such as mercury (Hg). During the Indian monsoon season of 2013, a total of 92 and 26 atmospheric water vapor samples were collected at Lhasa, the largest city of the Tibet, for Hg and major ions analysis, respectively. The relatively low pH/high electronic conductivity values, together with the fact that NH_4"+ in atmospheric water vapor was even higher than that determined in precipitation of Lhasa, indicated the effects of anthropogenic perturbations through long-range transboundary atmospheric transport. Concentrations of Hg in atmospheric water vapor ranged from 2.5 to 73.7 ng L"−"1, with an average of 12.5 ng L"−"1. The elevated Hg and major ions concentrations, and electronic conductivity values were generally associated with weak acidic samples, and Hg mainly loaded with anthropogenic ions such as NH_4"+. The results of principal component analysis and trajectory analysis suggested that anthropogenic emissions from the Indian subcontinent may have largely contributed to the determined Hg in atmospheric water vapor. Furthermore, our study reconfirmed that below-cloud scavenging contribution was significant for precipitation Hg in Lhasa, and evaluated that on average 74.1% of the Hg in precipitation could be accounted for by below-cloud scavenging. - Highlights: • The low pH/high electronic conductivity was found in atmospheric water vapor. • Anthropogenic NH_4"+ was higher than that determined in precipitation of Lhasa. • Elevated Hg and major ions levels were usually associated with weak acidic samples. • Hg in atmospheric water vapor was largely influenced by transboundary transport. • Below-cloud scavenging accounted for most Hg in precipitation.

  18. Medical Expenditure for Chronic Diseases in Mexico: The Case of Selected Diagnoses Treated by the Largest Care Providers

    Science.gov (United States)

    Figueroa-Lara, Alejandro; Gonzalez-Block, Miguel Angel; Alarcon-Irigoyen, Jose

    2016-01-01

    Background Chronic diseases (CD) are a public health emergency in Mexico. Despite concern regarding the financial burden of CDs in the country, economic studies have focused only on diabetes, hypertension, and cancer. Furthermore, these estimated financial burdens were based on hypothetical epidemiology models or ideal healthcare scenarios. The present study estimates the annual expenditure per patient and the financial burden for the nine most prevalent CDs, excluding cancer, for each of the two largest public health providers in the country: the Ministry of Health (MoH) and the Mexican Institute of Social Security (IMSS). Methods Using the Mexican National Health and Nutrition Survey 2012 (ENSANUT) as the main source of data, health services consumption related to CDs was obtained from patient reports. Unit costs for each provided health service (e.g. consultation, drugs, hospitalization) were obtained from official reports. Prevalence data was obtained from the published literature. Annual expenditure due to health services consumption was calculated by multiplying the quantity of services consumed by the unit cost of each health service. Results The most expensive CD in both health institutions was chronic kidney disease (CKD), with an annual unit cost for MoH per patient of US$ 8,966 while for IMSS the expenditure was US$ 9,091. Four CDs (CKD, arterial hypertension, type 2 diabetes, and chronic ischemic heart disease) accounted for 88% of the total CDs financial burden (US$ 1.42 billion) in MoH and 85% (US$ 3.96 billion) in IMSS. The financial burden of the nine CDs analyzed represents 8% and 25% of the total annual MoH and IMSS health expenditure, respectively. Conclusions/Significance The financial burden from the nine most prevalent CDs, excluding cancer, is already high in Mexico. This finding by itself argues for the need to improve health promotion and disease detection, diagnosis, and treatment to ensure CD primary and secondary prevention. If the

  19. Uptake and accumulation of potentially toxic elements in colonized plant species around the world's largest antimony mine area, China.

    Science.gov (United States)

    Long, Jiumei; Tan, Di; Deng, Sihan; Lei, Ming

    2018-04-11

    To provide information on reclamation of multi-heavy metal polluted soils with conception of phytostabilization, a field survey on the uptake and accumulation of potentially toxic elements such as antimony (Sb), arsenic (As), lead (Pb), cadmium (Cd), copper (Cu), and zinc (Zn) in colonized plant species around the world's largest antimony mine area, China, was conducted. Samples including leaves and shoots (including roots and stems) of colonized plants as well as rhizospheric soils were collected from eight sampling zones in the studied area. The results showed that the contents of Cu, Zn, and Pb in rhizospheric soils below plants were comparable to the corresponding background values of Hunan province, otherwise Sb, Cd, and As contents were extremely high (17-106, 17-87, and 3-7 times of the corresponding background values). The highest concentration of Sb was found in Aster subulatus (410 mg kg -1 ); Cd, As, and Zn were in Herba bidentis bipinnatae (10.9, 264, and 265 mg kg -1 , respectively); and Cu was in Artemisia lavandulaefolia (27.1 mg kg -1 ). It also exhibited that all the contents of As in leaves were several times of those in shoots of plants, Cd and other heavy metals showed in a similar pattern in several studied species, implying that the uptake route of these heavy metals via foliar might contribute to the accumulation. With high bioconcentration factors of heavy metals (more than 1, except for Zn), together with the growth abundance, Herba bidentis bipinnatae was considered as the most suitable colonized species for phytostabilization of the multi-heavy metal pollution in soils on this antimony mine area.

  20. Spatial and temporal activity patterns of the free-living giant mole-rat (Fukomys mechowii, the largest social bathyergid.

    Directory of Open Access Journals (Sweden)

    Matěj Lövy

    Full Text Available Despite the considerable attention devoted to the biology of social species of African mole-rats (Bathyergidae, Rodentia, knowledge is lacking about their behaviour under natural conditions. We studied activity of the largest social bathyergid, the giant mole-rat Fukomys mechowii, in its natural habitat in Zambia using radio-telemetry. We radio-tracked six individuals during three continuous 72-h sessions. Five of these individuals, including a breeding male, belonged to a single family group; the remaining female was probably a solitary disperser. The non-breeders of the family were active (i.e. outside the nest 5.8 hours per 24h-day with the activity split into 6.5 short bouts. The activity was more concentrated in the night hours, when the animals also travelled longer distances from the nest. The breeding male spent only 3.2 hours per day outside the nest, utilizing less than 20% of the whole family home range. The dispersing female displayed a much different activity pattern than the family members. Her 8.0 hours of outside-nest activity per day were split into 4.6 bouts which were twice as long as in the family non-breeders. Her activity peak in the late afternoon coincided with the temperature maximum in the depth of 10 cm (roughly the depth of the foraging tunnels. Our results suggest that the breeding individuals (at least males contribute very little to the work of the family group. Nevertheless, the amount of an individual's activity and its daily pattern are probably flexible in this species and can be modified in response to actual environmental and social conditions.

  1. What caused the decline of China's largest freshwater lake? Attribution analysis on Poyang Lake water level variations in recent years

    Science.gov (United States)

    Ye, Xuchun; Xu, Chong-Yu; Zhang, Qi

    2017-04-01

    In recent years, dramatic decline of water level of the Poyang Lake, China's largest freshwater lake, has raised wide concerns about the water security and wetland ecosystem. This remarkable hydrological change coincided with several factors like the initial operation of the Three Gorges Dam (TGD) in 2003, the big change of lake bottom topography due to extensive sand mining in the lake since 2000, and also climate change and other human activities in the Yangtze River basin may add to this complexity. Questions raised to what extent that the lake hydrological changes is caused by climate change and/or human activities. In this study, quantitative assessment was conducted to clarify the magnitude and mechanism of specific influencing factors on recent lake decline (2003-2014), with reference to the period of 1980-1999. The attempts were achieved through the reconstruction of lake water level scenarios by the framework of neural network. Major result indicates that the effect of lake bottom topography change due to sand mining activities has became the dominant factor for the recent lake decline, especially in winter season with low water level. However, the effect of TGD regulation shows strong seasonal features, its effect can accounts for 33%-42% of the average water level decline across the lake during the impoundment period of September-October. In addition, the effect of climate change and other human activities over the Yangtze River basin needs to be highly addressed, which is particularly prominent on reducing lake water level during the summer flood season and autumn recession period. The result also revealed that due to different mechanism, the responses of the lake water level to the three influencing factors are not consistent and show great spatial and temporal differences.

  2. Mapping changes in the largest continuous Amazonian mangrove belt using object-based classification of multisensor satellite imagery

    Science.gov (United States)

    Nascimento, Wilson R.; Souza-Filho, Pedro Walfir M.; Proisy, Christophe; Lucas, Richard M.; Rosenqvist, Ake

    2013-01-01

    Mapping and monitoring mangrove ecosystems is a crucial objective for tropical countries, particularly where human disturbance occurs and because of uncertainties associated with sea level and climatic fluctuation. In many tropical regions, such efforts have focused largely on the use of optical data despite low capture rates because of persistent cloud cover. Recognizing the ability of Synthetic Aperture Radar (SAR) for providing cloud-free observations, this study investigated the use of JERS-1 SAR and ALOS PALSAR data, acquired in 1996 and 2008 respectively, for mapping the extent of mangroves along the Brazilian coastline, from east of the Amazon River mouth, Pará State, to the Bay of São José in Maranhão. For each year, an object-orientated classification of major land covers (mangrove, secondary vegetation, gallery and swamp forest, open water, intermittent lakes and bare areas) was performed with the resulting maps then compared to quantify change. Comparison with available ground truth data indicated a general accuracy in the 2008 image classification of all land covers of 96% (kappa = 90.6%, tau = 92.6%). Over the 12 year period, the area of mangrove increased by 718.6 km2 from 6705 m2 to 7423.60 km2, with 1931.0 km² of expansion and 1213 km² of erosion noted; 5493 km² remained unchanged in extent. The general accuracy relating to changes in mangroves was 83.3% (Kappa 66.1%; tau 66.7%). The study confirmed that these mangroves constituted the largest continuous belt globally and were experiencing significant change because of the dynamic coastal environment and the influence of sedimentation from the Amazon River along the shoreline. The study recommends continued observations using combinations of SAR and optical data to establish trends in mangrove distributions and implications for provision of ecosystem services (e.g., fish/invertebrate nurseries, carbon storage and coastal protection).

  3. Medical Expenditure for Chronic Diseases in Mexico: The Case of Selected Diagnoses Treated by the Largest Care Providers.

    Science.gov (United States)

    Figueroa-Lara, Alejandro; Gonzalez-Block, Miguel Angel; Alarcon-Irigoyen, Jose

    2016-01-01

    Chronic diseases (CD) are a public health emergency in Mexico. Despite concern regarding the financial burden of CDs in the country, economic studies have focused only on diabetes, hypertension, and cancer. Furthermore, these estimated financial burdens were based on hypothetical epidemiology models or ideal healthcare scenarios. The present study estimates the annual expenditure per patient and the financial burden for the nine most prevalent CDs, excluding cancer, for each of the two largest public health providers in the country: the Ministry of Health (MoH) and the Mexican Institute of Social Security (IMSS). Using the Mexican National Health and Nutrition Survey 2012 (ENSANUT) as the main source of data, health services consumption related to CDs was obtained from patient reports. Unit costs for each provided health service (e.g. consultation, drugs, hospitalization) were obtained from official reports. Prevalence data was obtained from the published literature. Annual expenditure due to health services consumption was calculated by multiplying the quantity of services consumed by the unit cost of each health service. The most expensive CD in both health institutions was chronic kidney disease (CKD), with an annual unit cost for MoH per patient of US$ 8,966 while for IMSS the expenditure was US$ 9,091. Four CDs (CKD, arterial hypertension, type 2 diabetes, and chronic ischemic heart disease) accounted for 88% of the total CDs financial burden (US$ 1.42 billion) in MoH and 85% (US$ 3.96 billion) in IMSS. The financial burden of the nine CDs analyzed represents 8% and 25% of the total annual MoH and IMSS health expenditure, respectively. The financial burden from the nine most prevalent CDs, excluding cancer, is already high in Mexico. This finding by itself argues for the need to improve health promotion and disease detection, diagnosis, and treatment to ensure CD primary and secondary prevention. If the status quo remains, the financial burden could be higher.

  4. Influence of long-range transboundary transport on atmospheric water vapor mercury collected at the largest city of Tibet

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Jie [Key Laboratory of Tibetan Environment Changes and Land Surface Processes, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101 (China); CAS Center for Excellence in Tibetan Plateau Earth Sciences, Chinese Academy of Sciences, Beijing 100101 (China); Laboratory of Green Chemistry, Lappeenranta University of Technology, Sammonkatu 12, Mikkeli FI 50130 (Finland); Kang, Shichang, E-mail: shichang.kang@lzb.ac.cn [State Key Laboratory of Cryospheric Sciences, Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000 (China); CAS Center for Excellence in Tibetan Plateau Earth Sciences, Chinese Academy of Sciences, Beijing 100101 (China); Tian, Lide [Key Laboratory of Tibetan Environment Changes and Land Surface Processes, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101 (China); CAS Center for Excellence in Tibetan Plateau Earth Sciences, Chinese Academy of Sciences, Beijing 100101 (China); Guo, Junming [Key Laboratory of Tibetan Environment Changes and Land Surface Processes, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101 (China); Graduate University of the Chinese Academy of Sciences, Beijing 100049 (China); Zhang, Qianggong; Cong, Zhiyuan [Key Laboratory of Tibetan Environment Changes and Land Surface Processes, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101 (China); CAS Center for Excellence in Tibetan Plateau Earth Sciences, Chinese Academy of Sciences, Beijing 100101 (China); Sillanpää, Mika [Laboratory of Green Chemistry, Lappeenranta University of Technology, Sammonkatu 12, Mikkeli FI 50130 (Finland); and others

    2016-10-01

    Monsoon circulation is an important process that affects long-range transboundary transport of anthropogenic contaminants such as mercury (Hg). During the Indian monsoon season of 2013, a total of 92 and 26 atmospheric water vapor samples were collected at Lhasa, the largest city of the Tibet, for Hg and major ions analysis, respectively. The relatively low pH/high electronic conductivity values, together with the fact that NH{sub 4}{sup +} in atmospheric water vapor was even higher than that determined in precipitation of Lhasa, indicated the effects of anthropogenic perturbations through long-range transboundary atmospheric transport. Concentrations of Hg in atmospheric water vapor ranged from 2.5 to 73.7 ng L{sup −1}, with an average of 12.5 ng L{sup −1}. The elevated Hg and major ions concentrations, and electronic conductivity values were generally associated with weak acidic samples, and Hg mainly loaded with anthropogenic ions such as NH{sub 4}{sup +}. The results of principal component analysis and trajectory analysis suggested that anthropogenic emissions from the Indian subcontinent may have largely contributed to the determined Hg in atmospheric water vapor. Furthermore, our study reconfirmed that below-cloud scavenging contribution was significant for precipitation Hg in Lhasa, and evaluated that on average 74.1% of the Hg in precipitation could be accounted for by below-cloud scavenging. - Highlights: • The low pH/high electronic conductivity was found in atmospheric water vapor. • Anthropogenic NH{sub 4}{sup +} was higher than that determined in precipitation of Lhasa. • Elevated Hg and major ions levels were usually associated with weak acidic samples. • Hg in atmospheric water vapor was largely influenced by transboundary transport. • Below-cloud scavenging accounted for most Hg in precipitation.

  5. The 100-C-7 Remediation Project. An Overview of One of DOE's Largest Remediation Projects - 13260

    Energy Technology Data Exchange (ETDEWEB)

    Post, Thomas C. [U.S. Department of Energy Richland Operations Office, Richland, WA 99352 (United States); Strom, Dean [Washington Closure Hanford LLC, 2620 Fermi Avenue, Richland, WA 99354 (United States); Beulow, Laura [U.S. Environmental Protection Agency, 309 Bradley Boulevard, Suite 115, Richland, WA 99352 (United States)

    2013-07-01

    The U.S. Department of Energy Richland Operations Office (RL), U.S. Environmental Protection Agency (EPA) and Washington Closure Hanford LLC (WCH) completed remediation of one of the largest waste sites in the U.S. Department of Energy complex. The waste site, 100-C-7, covers approximately 15 football fields and was excavated to a depth of 85 feet (groundwater). The project team removed a total of 2.3 million tons of clean and contaminated soil, concrete debris, and scrap metal. 100-C-7 lies in Hanford's 100 B/C Area, home to historic B and C Reactors. The waste site was excavated in two parts as 100-C-7 and 100-C-7:1. The pair of excavations appear like pit mines. Mining engineers were hired to design their tiered sides, with safety benches every 17 feet and service ramps which allowed equipment access to the bottom of the excavations. The overall cleanup project was conducted over a span of almost 10 years. A variety of site characterization, excavation, load-out and sampling methodologies were employed at various stages of remediation. Alternative technologies were screened and evaluated during the project. A new method for cost effectively treating soils was implemented - resulting in significant cost savings. Additional opportunities for minimizing waste streams and recycling were identified and effectively implemented by the project team. During the final phase of cleanup the project team applied lessons learned throughout the entire project to address the final, remaining source of chromium contamination. The C-7 cleanup now serves as a model for remediating extensive deep zone contamination sites at Hanford. (authors)

  6. Satellite-derived submarine melt rates and mass balance (2011-2015) for Greenland's largest remaining ice tongues

    Science.gov (United States)

    Wilson, Nat; Straneo, Fiammetta; Heimbach, Patrick

    2017-12-01

    Ice-shelf-like floating extensions at the termini of Greenland glaciers are undergoing rapid changes with potential implications for the stability of upstream glaciers and the ice sheet as a whole. While submarine melting is recognized as a major contributor to mass loss, the spatial distribution of submarine melting and its contribution to the total mass balance of these floating extensions is incompletely known and understood. Here, we use high-resolution WorldView satellite imagery collected between 2011 and 2015 to infer the magnitude and spatial variability of melt rates under Greenland's largest remaining ice tongues - Nioghalvfjerdsbræ (79 North Glacier, 79N), Ryder Glacier (RG), and Petermann Glacier (PG). Submarine melt rates under the ice tongues vary considerably, exceeding 50 m a-1 near the grounding zone and decaying rapidly downstream. Channels, likely originating from upstream subglacial channels, give rise to large melt variations across the ice tongues. We compare the total melt rates to the influx of ice to the ice tongue to assess their contribution to the current mass balance. At Petermann Glacier and Ryder Glacier, we find that the combined submarine and aerial melt approximately balances the ice flux from the grounded ice sheet. At Nioghalvfjerdsbræ the total melt flux (14.2 ± 0.96 km3 a-1 w.e., water equivalent) exceeds the inflow of ice (10.2 ± 0.59 km3 a-1 w.e.), indicating present thinning of the ice tongue.

  7. The Effects of Largest Claim and Excess of Loss Reinsurance on a Company’s Ruin Time and Valuation

    Directory of Open Access Journals (Sweden)

    Yuguang Fan

    2017-01-01

    Full Text Available We compare two types of reinsurance: excess of loss (EOL and largest claim reinsurance (LCR, each of which transfers the payment of part, or all, of one or more large claims from the primary insurance company (the cedant to a reinsurer. The primary insurer’s point of view is documented in terms of assessment of risk and payment of reinsurance premium. A utility indifference rationale based on the expected future dividend stream is used to value the company with and without reinsurance. Assuming the classical compound Poisson risk model with choices of claim size distributions (classified as heavy, medium and light-tailed cases, simulations are used to illustrate the impact of the EOL and LCR treaties on the company’s ruin probability, ruin time and value as determined by the dividend discounting model. We find that LCR is at least as effective as EOL in averting ruin in comparable finite time horizon settings. In instances where the ruin probability for LCR is smaller than for EOL, the dividend discount model shows that the cedant is able to pay a larger portion of the dividend for LCR reinsurance than for EOL while still maintaining company value. Both methods reduce risk considerably as compared with no reinsurance, in a variety of situations, as measured by the standard deviation of the company value. A further interesting finding is that heaviness of tails alone is not necessarily the decisive factor in the possible ruin of a company; small and moderate sized claims can also play a significant role in this.

  8. Medical Expenditure for Chronic Diseases in Mexico: The Case of Selected Diagnoses Treated by the Largest Care Providers.

    Directory of Open Access Journals (Sweden)

    Alejandro Figueroa-Lara

    Full Text Available Chronic diseases (CD are a public health emergency in Mexico. Despite concern regarding the financial burden of CDs in the country, economic studies have focused only on diabetes, hypertension, and cancer. Furthermore, these estimated financial burdens were based on hypothetical epidemiology models or ideal healthcare scenarios. The present study estimates the annual expenditure per patient and the financial burden for the nine most prevalent CDs, excluding cancer, for each of the two largest public health providers in the country: the Ministry of Health (MoH and the Mexican Institute of Social Security (IMSS.Using the Mexican National Health and Nutrition Survey 2012 (ENSANUT as the main source of data, health services consumption related to CDs was obtained from patient reports. Unit costs for each provided health service (e.g. consultation, drugs, hospitalization were obtained from official reports. Prevalence data was obtained from the published literature. Annual expenditure due to health services consumption was calculated by multiplying the quantity of services consumed by the unit cost of each health service.The most expensive CD in both health institutions was chronic kidney disease (CKD, with an annual unit cost for MoH per patient of US$ 8,966 while for IMSS the expenditure was US$ 9,091. Four CDs (CKD, arterial hypertension, type 2 diabetes, and chronic ischemic heart disease accounted for 88% of the total CDs financial burden (US$ 1.42 billion in MoH and 85% (US$ 3.96 billion in IMSS. The financial burden of the nine CDs analyzed represents 8% and 25% of the total annual MoH and IMSS health expenditure, respectively.The financial burden from the nine most prevalent CDs, excluding cancer, is already high in Mexico. This finding by itself argues for the need to improve health promotion and disease detection, diagnosis, and treatment to ensure CD primary and secondary prevention. If the status quo remains, the financial burden could be

  9. CLASH: COMPLETE LENSING ANALYSIS OF THE LARGEST COSMIC LENS MACS J0717.5+3745 AND SURROUNDING STRUCTURES

    International Nuclear Information System (INIS)

    Medezinski, Elinor; Lemze, Doron; Ford, Holland; Umetsu, Keiichi; Nonino, Mario; Merten, Julian; Mroczkowski, Tony; Zitrin, Adi; Broadhurst, Tom; Donahue, Megan; Sayers, Jack; Czakon, Nicole; Waizmann, Jean-Claude; Meneghetti, Massimo; Koekemoer, Anton; Coe, Dan; Postman, Marc; Molino, Alberto; Melchior, Peter; Grillo, Claudio

    2013-01-01

    The galaxy cluster MACS J0717.5+3745 (z = 0.55) is the largest known cosmic lens, with complex internal structures seen in deep X-ray, Sunyaev-Zel'dovich effect, and dynamical observations. We perform a combined weak- and strong-lensing analysis with wide-field BVR c i'z' Subaru/Suprime-Cam observations and 16-band Hubble Space Telescope observations taken as part of the Cluster Lensing And Supernova survey with Hubble. We find consistent weak distortion and magnification measurements of background galaxies and combine these signals to construct an optimally estimated radial mass profile of the cluster and its surrounding large-scale structure out to 5 Mpc h –1 . We find consistency between strong-lensing and weak-lensing in the region where these independent data overlap, –1 . The two-dimensional weak-lensing map reveals a clear filamentary structure traced by distinct mass halos. We model the lensing shear field with nine halos, including the main cluster, corresponding to mass peaks detected above 2.5σ κ . The total mass of the cluster as determined by the different methods is M vir ≈ (2.8 ± 0.4) × 10 15 M ☉ . Although this is the most massive cluster known at z > 0.5, in terms of extreme value statistics, we conclude that the mass of MACS J0717.5+3745 by itself is not in serious tension with ΛCDM, representing only a ∼2σ departure above the maximum simulated halo mass at this redshift

  10. CLASH: COMPLETE LENSING ANALYSIS OF THE LARGEST COSMIC LENS MACS J0717.5+3745 AND SURROUNDING STRUCTURES

    Energy Technology Data Exchange (ETDEWEB)

    Medezinski, Elinor; Lemze, Doron; Ford, Holland [Department of Physics and Astronomy, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States); Umetsu, Keiichi [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Nonino, Mario [INAF/Osservatorio Astronomico di Trieste, via G.B. Tiepolo 11, I-34143 Trieste (Italy); Merten, Julian; Mroczkowski, Tony [Jet Propulsion Laboratory, California Institute of Technology, MS 169-327, Pasadena, CA 91109 (United States); Zitrin, Adi [Institut für Theoretische Astrophysik, Universität Heidelberg, Zentrum für Astronomie, Philosophenweg 12, D-69120 Heidelberg (Germany); Broadhurst, Tom [Department of Theoretical Physics and History of Science, University of the Basque Country UPV/EHU, P.O. Box 644, E-48080 Bilbao (Spain); Donahue, Megan [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Sayers, Jack; Czakon, Nicole [Division of Physics, Math, and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Waizmann, Jean-Claude; Meneghetti, Massimo [Dipartimento di Astronomia, Universit' a di Bologna, via Ranzani 1, I-40127 Bologna (Italy); Koekemoer, Anton; Coe, Dan; Postman, Marc [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21208 (United States); Molino, Alberto [Instituto de Astrofísica de Andalucía (CSIC), E-18080 Granada (Spain); Melchior, Peter [Center for Cosmology and Astro-Particle Physics and Department of Physics, The Ohio State University, Columbus, OH 43210 (United States); Grillo, Claudio, E-mail: elinor@pha.jhu.edu [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Mariesvej 30, DK-2100 Copenhagen (Denmark); and others

    2013-11-01

    The galaxy cluster MACS J0717.5+3745 (z = 0.55) is the largest known cosmic lens, with complex internal structures seen in deep X-ray, Sunyaev-Zel'dovich effect, and dynamical observations. We perform a combined weak- and strong-lensing analysis with wide-field BVR{sub c} i'z' Subaru/Suprime-Cam observations and 16-band Hubble Space Telescope observations taken as part of the Cluster Lensing And Supernova survey with Hubble. We find consistent weak distortion and magnification measurements of background galaxies and combine these signals to construct an optimally estimated radial mass profile of the cluster and its surrounding large-scale structure out to 5 Mpc h {sup –1}. We find consistency between strong-lensing and weak-lensing in the region where these independent data overlap, <500 kpc h {sup –1}. The two-dimensional weak-lensing map reveals a clear filamentary structure traced by distinct mass halos. We model the lensing shear field with nine halos, including the main cluster, corresponding to mass peaks detected above 2.5σ{sub κ}. The total mass of the cluster as determined by the different methods is M{sub vir} ≈ (2.8 ± 0.4) × 10{sup 15} M{sub ☉}. Although this is the most massive cluster known at z > 0.5, in terms of extreme value statistics, we conclude that the mass of MACS J0717.5+3745 by itself is not in serious tension with ΛCDM, representing only a ∼2σ departure above the maximum simulated halo mass at this redshift.

  11. Assessment of the Hydro-Ecological Impacts of the Three Gorges Dam on China’s Largest Freshwater Lake

    Directory of Open Access Journals (Sweden)

    Guiping Wu

    2017-10-01

    Full Text Available The Three Gorges Dam (TGD has received increasing attention with respect to its potential effects on downstream hydro-ecosystems. Poyang Lake is the largest freshwater lake downstream of the TGD, and it is not immune to these impacts. Here, we combine hydrological observations, remote sensing, a geographic information system (GIS, and landscape ecology technology to investigate the variability and spatial pattern of the hydro-ecological alterations to Poyang Lake induced by the operation of the TGD. It was found that the TGD caused significant hydro-ecological alterations across the Poyang Lake wetland. Specifically, the TGD operation altered the seasonal inundation pattern of Poyang Lake and significantly reduced the monthly inundation frequencies (IFs, which were especially notable (~30–40% from September to November. Spatially, the declining IFs led to an increase in the mudflat area that is suitable for the growth of vegetation. The vegetation area increased by 58.82 km2 and 463.73 km2 in the low- and high-water season, respectively, with the most significant changes occurring in the estuary delta of the Ganjiang and Raohe rivers. The results also indicated that the changes in the inundation pattern and floodplain vegetation have profoundly altered the structure and composition of the wetland, which has resulted in increased landscape diversity and a gradual increase in the complexity of the ecosystem composition under the influence of regulation of the TGD. Such results are of great importance for policymakers, as they may provide a reference for wetland water resource planning and landscape restoration in an operational dam environment.

  12. Dioxins and Nonortho PCBs in Breast Milk of Vietnamese Mothers Living in the Largest Hot Spot of Dioxin Contamination.

    Science.gov (United States)

    Nghi, Tran Ngoc; Nishijo, Muneko; Manh, Ho Dung; Tai, Pham The; Van Luong, Hoang; Anh, Tran Hai; Thao, Pham Ngoc; Trung, Nguyen Viet; Waseda, Tomoo; Nakagawa, Hideaki; Kido, Teruhiko; Nishijo, Hisao

    2015-05-05

    Bien Hoa Air Base is the largest dioxin contamination hot spot in Vietnam. In 2012, we recruited 216 mothers who were living in 10 communities around Bien Hoa Air Base and had delivered newborns at a prefecture hospital, and we investigated recent exposure levels of dioxins and nonortho PCBs in their breast milk. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-tetraCDD) was present at 2.6 pg/g lipid in primiparae and 2.2 pg/g lipid in multiparae. Among multiparae and total subjects, significant high prevalence of 2,3,7,8-tetraCDD≥5 pg/g lipid and 2,3,7,8-tetraCDD contribution≥40% were observed in mothers living in the five communities closest to Bien Hoa Air Base. The TEQ for nonortho PCBs was 1.6 pg-TEQ/g lipid for primiparae, and this was even lower than that in the unsprayed area. The length of residency was a strong factor to increase dioxins, including 2,3,7,8-tetraCDD. Residency in the five communities with the highest exposure was a specific risk factor for increased 2,3,7,8-tetraCDD in breast milk. Food intake might contribute partly to the increased levels of dioxin congeners other than 2,3,7,8-tetraCDD in breast milk. These results suggest that Bien Hoa Air Base has led to elevated 2,3,7,8-tetraCDD levels in breast milk of mothers in nearby areas even in the recent years.

  13. Functional form for the leading correction to the distribution of the largest eigenvalue in the GUE and LUE

    Science.gov (United States)

    Forrester, Peter J.; Trinh, Allan K.

    2018-05-01

    The neighbourhood of the largest eigenvalue λmax in the Gaussian unitary ensemble (GUE) and Laguerre unitary ensemble (LUE) is referred to as the soft edge. It is known that there exists a particular centring and scaling such that the distribution of λmax tends to a universal form, with an error term bounded by 1/N2/3. We take up the problem of computing the exact functional form of the leading error term in a large N asymptotic expansion for both the GUE and LUE—two versions of the LUE are considered, one with the parameter a fixed and the other with a proportional to N. Both settings in the LUE case allow for an interpretation in terms of the distribution of a particular weighted path length in a model involving exponential variables on a rectangular grid, as the grid size gets large. We give operator theoretic forms of the corrections, which are corollaries of knowledge of the first two terms in the large N expansion of the scaled kernel and are readily computed using a method due to Bornemann. We also give expressions in terms of the solutions of particular systems of coupled differential equations, which provide an alternative method of computation. Both characterisations are well suited to a thinned generalisation of the original ensemble, whereby each eigenvalue is deleted independently with probability (1 - ξ). In Sec. V, we investigate using simulation the question of whether upon an appropriate centring and scaling a wider class of complex Hermitian random matrix ensembles have their leading correction to the distribution of λmax proportional to 1/N2/3.

  14. Drought, Frost, Rain and Sunshine. Four Years of Sap Flow Measurements for One of the World's Largest Conifers

    Science.gov (United States)

    Macinnis-Ng, C.; Taylor, D. T.; Kaplick, J.; Clearwater, M.

    2015-12-01

    Amongst the largest and longest lived conifers in the world, the endemic New Zealand kauri, Agathis australis, provides a proxy-climate record dating back 4000 y. Tree-ring widths provide a strong indicator of the occurrence of El Niño Southern Oscillation (ENSO) events. We are measuring physiological processes, including carbon uptake and loss, leaf-scale gas exchange and sap flow together with meteorological data to explore the mechanisms of the climate response of this iconic and culturally significant species. In this continuous 15 min time interval sap flow dataset spanning four years, we have captured very wet and very dry summer periods. Winter flow rates peaked lower than summer flow rates and winter flow also started later and finished earlier in the day, resulting in less water use. Larger, canopy dominant trees (DBH up to 176 cm) had large sapwood area (sapwood depth up to 18 cm) and faster flow rates and therefore dominated stand water use. During dry periods, smaller trees (DBH 20-80 cm) were more responsive to dry soils than larger trees, suggesting access to deeper soil water stores. Leaf-scale gas exchange rates were low with very low stomatal conductance values reflecting known vulnerability to xylem embolism. Night-time refilling of sapwood was particularly evident during the summer drought with evidence that refilling was incomplete as the drought progressed. Photosynthetically active radiation and vapour pressure deficit are strongly correlated with sap flow across all seasons, a promising indicator for future modelling work on this dataset. Water saving strategies and stand-scale water budgets are discussed.

  15. Hoplitolyda duolunica gen. et sp. nov. (Insecta, Hymenoptera, Praesiricidae, the Hitherto largest sawfly from the Mesozoic of China.

    Directory of Open Access Journals (Sweden)

    Taiping Gao

    Full Text Available BACKGROUND: Large body size of an insect, in general, enhances its capability of predation, competition, and defense, resulting in better survivability and reproduction. Hymenopterans, most being phytophagous or parasitic, have a relatively small to medium body size, typically under 50.0 mm in body length. PRINCIPAL FINDINGS: Herein, we describe Hoplitolyda duolunica gen. et sp. nov., assigned to Praesiricidae, from the Early Cretaceous Yixian Formation of China. This new species is the largest fossil hymenopteran hitherto with body estimated >55.0 mm long and wing span >92.0 mm. H. duolunica is, to our knowledge, the only sawfly with Sc present in the hind wing but not in the forewing. Its Rs1 and M1 meeting each other at 145° angle represents an intermediate in the transition from "Y" to "T" shapes. Even though Hoplitolyda differs significantly from all previously described genera in two subfamilies of Praesricidae, we leave the new genus unplaced in existing subfamilies, pending discovery of material with more taxonomic structure. CONCLUSIONS/SIGNIFICANCE: Hoplitolyda has many unique and interesting characters which might have benefitted its competition, survival, and reproduction: large body size and head with robust and strong mandibles for defense and/or sexual selection, unique wing venation and setal arrangements for flight capability and mobility, dense hairs on body and legs for sensing and protection, etc. Considering the reported ferocious predators of feathered dinosaurs, pterosaurs, birds, and mammals coexisting in the same eco-system, Hoplitolyda is an interesting case of "survival of the fittest" in facing its evolutionary challenges.

  16. The Philip Morris Genome Project: a guide to tracking alliances of the world´s largest cigarette company

    Directory of Open Access Journals (Sweden)

    Alan Blum

    2018-03-01

    Full Text Available Background Beginning in the 1980s, tobacco control efforts shifted from school-based and clinic-based education about the dangers of smoking to direct confrontation of the tobacco industry. But the industry also evolved by developing innovative promotional campaigns, adopting new corporate identities, and forging alliances with other industries and charitable organizations. Methods To document the extent of the commercial, civic, political, academic, military,and cultural ties cultivated by the world´s largest cigarette manufacturer, Philip Morris, a continuous, 35-year ethnographic analysis was conducted, involving daily monitoring of the global business press; monthly review of tobacco industry trade publications; scrutiny of annual company reports; and attendance at 20 shareholders´ meetings, four international tobacco industry trade expositions, and over 200 sports, arts, and ethnic minority events sponsored by the company. Results 48 Philip Morris manufacturing facilities in 32 countries produce more than 800 billion cigarettes a year for 180 markets..A pioneer in sponsoring popular programs on the new medium of television in the 1950s; the company circumvented the 1971 ban on TV cigarette advertising by creating sporting events that were internationally televised. By acquiring beer and food companies In the 1980s, Philip Morris retained influence over the mass media covetous of advertising revenue. In 2002 the company changed its name to Altria to diminish the tobacco stigma. It makes the world´s top cigarette brand, Marlboro, and holds 28% of the global market excluding China. The company has forged an extensive network of alliances with agricultural, marketing, chemical, pharmaceutical, financial, packaging, entertainment, shipping, and technology companies, as well as ties to hundreds of museums, arts organizations, universities, libraries, and charities combating problems such as domestic violence, hunger, pollution, illiteracy, and

  17. Hindlimb musculature of the largest living rodent Hydrochoerus hydrochaeris (Caviomorpha): Adaptations to semiaquatic and terrestrial styles of life.

    Science.gov (United States)

    García-Esponda, César M; Candela, Adriana M

    2016-03-01

    The caviomorph species Hydrochoerus hydrochaeris (Cavioidea), or capybara, is the largest living rodent. This species is widely distributed, from northern South America to Uruguay and eastern Argentina, inhabiting in a wide variety of densely vegetated lowlands habitats in the proximity of water. Hydrochoerus hydrochaeris not only runs with agility, like other members of the Cavioidea, but it can also swim and dive easily. For these reasons, it has been classified as a cursorial as well as semiaquatic species. However, comprehensive anatomical descriptions of the osteology and myology of the capybara are not available in the literature and analyses on its swimming abilities are still required. We hypothesize that some of the characters of the hindlimb of H. hydrochaeris could reveal a unique morphological arrangement associated with swimming abilities. In this study, an anatomical description of the hindlimb musculature of H. hydrochaeris, and a discussion of the possible functional significance of the main muscles is provided. In addition, we explore the evolution of some myological and osteological characters of the capybara in the context of the cavioids. We concluded that most of the muscular and osteological features of the hindlimb of H. hydrochaeris are neither adaptations to a specialized cursoriality, nor major modifications for an aquatic mode of life. Hydrochoerus hydrochaeris share several features with other cavioids, being a generalized cursorial species in the context of this clade. However, it shows some adaptations of the hindlimb for enhancing propulsion through water, of which the most notable seems to be the shortening of the leg, short tendons of most muscles of the leg, and a well-developed soleus muscle. These adaptations to a semiaquatic mode of life could have been acquired during the most recent evolutionary history of the hydrochoerids. © 2015 Wiley Periodicals, Inc.

  18. A comparative study of the mobile population in Wuhan and other major cities.

    Science.gov (United States)

    Zeng, Y

    1997-01-01

    This study examined population mobility among residents of 5 cities in China: Wuhan, Beijing, Shanghai, Guangzhou, and Shenzhen. Data were obtained from the 1995 Sample Survey of 1% of Wuhan Population and provincial Statistical Yearbooks. The total mobile population in China has increased from 20-80 million during 1982-95. Shanghai is the largest Chinese city. Beijing has a large proportion of international and internal migrants. Guangzhou is a capital city that was the first to adopt economic reforms. Migration fueled development in Shenzhen. A larger mobile population was related to larger population density. The mobile population was 20% in all cities, 30% of central city population, and 140.5% of the central city of Shenzhen. Beijing and Shanghai had the highest growth rates. Construction accounts for the largest percentage of business-related mobile population in Wuhan, Beijing, and Shanghai. Manufacturing accounts for the largest percentage in Guangzhou and Shenzhen. Most of the mobile population in capital cities such as Wuhan and Guangzhou, originates from within the provinces. The largest percentage of mobile population in Beijing and Shanghai come from adjacent provinces. Guangzhou receives many migrants from adjacent Hong Kong, Macao, and Taiwan. 47.8-78.8% of mobile population were farmers. More migrants are men. Educational levels are low. The mobile population contributes to industry and informational/cultural exchange. The migrants detract from urban areas in population pressure on housing and services, shortages of employment, illegal activities and crime, and unplanned births.

  19. Advanced Cancer Detection Center

    National Research Council Canada - National Science Library

    Ruckdeschel, John

    1999-01-01

    ... through screening, and the testing of methods to prevent cancer. In addition, the Center created and supports education programs to provide increased cancer awareness and established working collaborations with the James...

  20. Advanced Missile Signature Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Missile Signature Center (AMSC) is a national facility supporting the Missile Defense Agency (MDA) and other DoD programs and customers with analysis,...