WorldWideScience

Sample records for large number statistics

  1. Gentile statistics with a large maximum occupation number

    International Nuclear Information System (INIS)

    Dai Wusheng; Xie Mi

    2004-01-01

    In Gentile statistics the maximum occupation number can take on unrestricted integers: 1 1 the Bose-Einstein case is not recovered from Gentile statistics as n goes to N. Attention is also concentrated on the contribution of the ground state which was ignored in related literature. The thermodynamic behavior of a ν-dimensional Gentile ideal gas of particle of dispersion E=p s /2m, where ν and s are arbitrary, is analyzed in detail. Moreover, we provide an alternative derivation of the partition function for Gentile statistics

  2. Improved estimation of the noncentrality parameter distribution from a large number of t-statistics, with applications to false discovery rate estimation in microarray data analysis.

    Science.gov (United States)

    Qu, Long; Nettleton, Dan; Dekkers, Jack C M

    2012-12-01

    Given a large number of t-statistics, we consider the problem of approximating the distribution of noncentrality parameters (NCPs) by a continuous density. This problem is closely related to the control of false discovery rates (FDR) in massive hypothesis testing applications, e.g., microarray gene expression analysis. Our methodology is similar to, but improves upon, the existing approach by Ruppert, Nettleton, and Hwang (2007, Biometrics, 63, 483-495). We provide parametric, nonparametric, and semiparametric estimators for the distribution of NCPs, as well as estimates of the FDR and local FDR. In the parametric situation, we assume that the NCPs follow a distribution that leads to an analytically available marginal distribution for the test statistics. In the nonparametric situation, we use convex combinations of basis density functions to estimate the density of the NCPs. A sequential quadratic programming procedure is developed to maximize the penalized likelihood. The smoothing parameter is selected with the approximate network information criterion. A semiparametric estimator is also developed to combine both parametric and nonparametric fits. Simulations show that, under a variety of situations, our density estimates are closer to the underlying truth and our FDR estimates are improved compared with alternative methods. Data-based simulations and the analyses of two microarray datasets are used to evaluate the performance in realistic situations. © 2012, The International Biometric Society.

  3. The use of mass spectrometry for analysing metabolite biomarkers in epidemiology: methodological and statistical considerations for application to large numbers of biological samples.

    Science.gov (United States)

    Lind, Mads V; Savolainen, Otto I; Ross, Alastair B

    2016-08-01

    Data quality is critical for epidemiology, and as scientific understanding expands, the range of data available for epidemiological studies and the types of tools used for measurement have also expanded. It is essential for the epidemiologist to have a grasp of the issues involved with different measurement tools. One tool that is increasingly being used for measuring biomarkers in epidemiological cohorts is mass spectrometry (MS), because of the high specificity and sensitivity of MS-based methods and the expanding range of biomarkers that can be measured. Further, the ability of MS to quantify many biomarkers simultaneously is advantageously compared to single biomarker methods. However, as with all methods used to measure biomarkers, there are a number of pitfalls to consider which may have an impact on results when used in epidemiology. In this review we discuss the use of MS for biomarker analyses, focusing on metabolites and their application and potential issues related to large-scale epidemiology studies, the use of MS "omics" approaches for biomarker discovery and how MS-based results can be used for increasing biological knowledge gained from epidemiological studies. Better understanding of the possibilities and possible problems related to MS-based measurements will help the epidemiologist in their discussions with analytical chemists and lead to the use of the most appropriate statistical tools for these data.

  4. Large number discrimination by mosquitofish.

    Directory of Open Access Journals (Sweden)

    Christian Agrillo

    Full Text Available BACKGROUND: Recent studies have demonstrated that fish display rudimentary numerical abilities similar to those observed in mammals and birds. The mechanisms underlying the discrimination of small quantities (<4 were recently investigated while, to date, no study has examined the discrimination of large numerosities in fish. METHODOLOGY/PRINCIPAL FINDINGS: Subjects were trained to discriminate between two sets of small geometric figures using social reinforcement. In the first experiment mosquitofish were required to discriminate 4 from 8 objects with or without experimental control of the continuous variables that co-vary with number (area, space, density, total luminance. Results showed that fish can use the sole numerical information to compare quantities but that they preferentially use cumulative surface area as a proxy of the number when this information is available. A second experiment investigated the influence of the total number of elements to discriminate large quantities. Fish proved to be able to discriminate up to 100 vs. 200 objects, without showing any significant decrease in accuracy compared with the 4 vs. 8 discrimination. The third experiment investigated the influence of the ratio between the numerosities. Performance was found to decrease when decreasing the numerical distance. Fish were able to discriminate numbers when ratios were 1:2 or 2:3 but not when the ratio was 3:4. The performance of a sample of undergraduate students, tested non-verbally using the same sets of stimuli, largely overlapped that of fish. CONCLUSIONS/SIGNIFICANCE: Fish are able to use pure numerical information when discriminating between quantities larger than 4 units. As observed in human and non-human primates, the numerical system of fish appears to have virtually no upper limit while the numerical ratio has a clear effect on performance. These similarities further reinforce the view of a common origin of non-verbal numerical systems in all

  5. A Career in Statistics Beyond the Numbers

    CERN Document Server

    Hahn, Gerald J

    2012-01-01

    A valuable guide to a successful career as a statistician A Career in Statistics: Beyond the Numbers prepares readers for careers in statistics by emphasizing essential concepts and practices beyond the technical tools provided in standard courses and texts. This insider's guide from internationally recognized applied statisticians helps readers decide whether a career in statistics is right for them, provides hands-on guidance on how to prepare for such a career, and shows how to succeed on the job. The book provides non-technical guidance for a successful career. The authors' extensive indu

  6. Photon-number statistics in resonance fluorescence

    Science.gov (United States)

    Lenstra, D.

    1982-12-01

    The theory of photon-number statistics in resonance fluorescence is treated, starting with the general formula for the emission probability of n photons during a given time interval T. The results fully confirm formerly obtained results by Cook that were based on the theory of atomic motion in a traveling wave. General expressions for the factorial moments are derived and explicit results for the mean and the variance are given. It is explicitly shown that the distribution function tends to a Gaussian when T becomes much larger than the natural lifetime of the excited atom. The speed of convergence towards the Gaussian is found to be typically slow, that is, the third normalized central moment (or the skewness) is proportional to T-12. However, numerical results illustrate that the overall features of the distribution function are already well represented by a Gaussian when T is larger than a few natural lifetimes only, at least if the intensity of the exciting field is not too small and its detuning is not too large.

  7. Forecasting distribution of numbers of large fires

    Science.gov (United States)

    Eidenshink, Jeffery C.; Preisler, Haiganoush K.; Howard, Stephen; Burgan, Robert E.

    2014-01-01

    Systems to estimate forest fire potential commonly utilize one or more indexes that relate to expected fire behavior; however they indicate neither the chance that a large fire will occur, nor the expected number of large fires. That is, they do not quantify the probabilistic nature of fire danger. In this work we use large fire occurrence information from the Monitoring Trends in Burn Severity project, and satellite and surface observations of fuel conditions in the form of the Fire Potential Index, to estimate two aspects of fire danger: 1) the probability that a 1 acre ignition will result in a 100+ acre fire, and 2) the probabilities of having at least 1, 2, 3, or 4 large fires within a Predictive Services Area in the forthcoming week. These statistical processes are the main thrust of the paper and are used to produce two daily national forecasts that are available from the U.S. Geological Survey, Earth Resources Observation and Science Center and via the Wildland Fire Assessment System. A validation study of our forecasts for the 2013 fire season demonstrated good agreement between observed and forecasted values.

  8. Statistics of geodesics in large quadrangulations

    International Nuclear Information System (INIS)

    Bouttier, J; Guitter, E

    2008-01-01

    We study the statistical properties of geodesics, i.e. paths of minimal length, in large random planar quadrangulations. We extend Schaeffer's well-labeled tree bijection to the case of quadrangulations with a marked geodesic, leading to the notion of 'spine trees', amenable to a direct enumeration. We obtain the generating functions for quadrangulations with a marked geodesic of fixed length, as well as with a set of 'confluent geodesics', i.e. a collection of non-intersecting minimal paths connecting two given points. In the limit of quadrangulations with a large area n, we find in particular an average number 3 x 2 i of geodesics between two fixed points at distance i >> 1 from each other. We show that, for generic endpoints, two confluent geodesics remain close to each other and have an extensive number of contacts. This property fails for a few 'exceptional' endpoints which can be linked by truly distinct geodesics. Results are presented both in the case of finite length i and in the scaling limit i ∼ n 1/4 . In particular, we give the scaling distribution of the exceptional points

  9. The large deviation approach to statistical mechanics

    International Nuclear Information System (INIS)

    Touchette, Hugo

    2009-01-01

    The theory of large deviations is concerned with the exponential decay of probabilities of large fluctuations in random systems. These probabilities are important in many fields of study, including statistics, finance, and engineering, as they often yield valuable information about the large fluctuations of a random system around its most probable state or trajectory. In the context of equilibrium statistical mechanics, the theory of large deviations provides exponential-order estimates of probabilities that refine and generalize Einstein's theory of fluctuations. This review explores this and other connections between large deviation theory and statistical mechanics, in an effort to show that the mathematical language of statistical mechanics is the language of large deviation theory. The first part of the review presents the basics of large deviation theory, and works out many of its classical applications related to sums of random variables and Markov processes. The second part goes through many problems and results of statistical mechanics, and shows how these can be formulated and derived within the context of large deviation theory. The problems and results treated cover a wide range of physical systems, including equilibrium many-particle systems, noise-perturbed dynamics, nonequilibrium systems, as well as multifractals, disordered systems, and chaotic systems. This review also covers many fundamental aspects of statistical mechanics, such as the derivation of variational principles characterizing equilibrium and nonequilibrium states, the breaking of the Legendre transform for nonconcave entropies, and the characterization of nonequilibrium fluctuations through fluctuation relations.

  10. The large deviation approach to statistical mechanics

    Science.gov (United States)

    Touchette, Hugo

    2009-07-01

    The theory of large deviations is concerned with the exponential decay of probabilities of large fluctuations in random systems. These probabilities are important in many fields of study, including statistics, finance, and engineering, as they often yield valuable information about the large fluctuations of a random system around its most probable state or trajectory. In the context of equilibrium statistical mechanics, the theory of large deviations provides exponential-order estimates of probabilities that refine and generalize Einstein’s theory of fluctuations. This review explores this and other connections between large deviation theory and statistical mechanics, in an effort to show that the mathematical language of statistical mechanics is the language of large deviation theory. The first part of the review presents the basics of large deviation theory, and works out many of its classical applications related to sums of random variables and Markov processes. The second part goes through many problems and results of statistical mechanics, and shows how these can be formulated and derived within the context of large deviation theory. The problems and results treated cover a wide range of physical systems, including equilibrium many-particle systems, noise-perturbed dynamics, nonequilibrium systems, as well as multifractals, disordered systems, and chaotic systems. This review also covers many fundamental aspects of statistical mechanics, such as the derivation of variational principles characterizing equilibrium and nonequilibrium states, the breaking of the Legendre transform for nonconcave entropies, and the characterization of nonequilibrium fluctuations through fluctuation relations.

  11. A course in mathematical statistics and large sample theory

    CERN Document Server

    Bhattacharya, Rabi; Patrangenaru, Victor

    2016-01-01

    This graduate-level textbook is primarily aimed at graduate students of statistics, mathematics, science, and engineering who have had an undergraduate course in statistics, an upper division course in analysis, and some acquaintance with measure theoretic probability. It provides a rigorous presentation of the core of mathematical statistics. Part I of this book constitutes a one-semester course on basic parametric mathematical statistics. Part II deals with the large sample theory of statistics — parametric and nonparametric, and its contents may be covered in one semester as well. Part III provides brief accounts of a number of topics of current interest for practitioners and other disciplines whose work involves statistical methods. Large Sample theory with many worked examples, numerical calculations, and simulations to illustrate theory Appendices provide ready access to a number of standard results, with many proofs Solutions given to a number of selected exercises from Part I Part II exercises with ...

  12. Forecasting distribution of numbers of large fires

    Science.gov (United States)

    Haiganoush K. Preisler; Jeff Eidenshink; Stephen Howard; Robert E. Burgan

    2015-01-01

    Systems to estimate forest fire potential commonly utilize one or more indexes that relate to expected fire behavior; however they indicate neither the chance that a large fire will occur, nor the expected number of large fires. That is, they do not quantify the probabilistic nature of fire danger. In this work we use large fire occurrence information from the...

  13. Thermal convection for large Prandtl numbers

    NARCIS (Netherlands)

    Grossmann, Siegfried; Lohse, Detlef

    2001-01-01

    The Rayleigh-Bénard theory by Grossmann and Lohse [J. Fluid Mech. 407, 27 (2000)] is extended towards very large Prandtl numbers Pr. The Nusselt number Nu is found here to be independent of Pr. However, for fixed Rayleigh numbers Ra a maximum in the Nu(Pr) dependence is predicted. We moreover offer

  14. Large number discrimination in newborn fish.

    Directory of Open Access Journals (Sweden)

    Laura Piffer

    Full Text Available Quantitative abilities have been reported in a wide range of species, including fish. Recent studies have shown that adult guppies (Poecilia reticulata can spontaneously select the larger number of conspecifics. In particular the evidence collected in literature suggest the existence of two distinct systems of number representation: a precise system up to 4 units, and an approximate system for larger numbers. Spontaneous numerical abilities, however, seem to be limited to 4 units at birth and it is currently unclear whether or not the large number system is absent during the first days of life. In the present study, we investigated whether newborn guppies can be trained to discriminate between large quantities. Subjects were required to discriminate between groups of dots with a 0.50 ratio (e.g., 7 vs. 14 in order to obtain a food reward. To dissociate the roles of number and continuous quantities that co-vary with numerical information (such as cumulative surface area, space and density, three different experiments were set up: in Exp. 1 number and continuous quantities were simultaneously available. In Exp. 2 we controlled for continuous quantities and only numerical information was available; in Exp. 3 numerical information was made irrelevant and only continuous quantities were available. Subjects successfully solved the tasks in Exp. 1 and 2, providing the first evidence of large number discrimination in newborn fish. No discrimination was found in experiment 3, meaning that number acuity is better than spatial acuity. A comparison with the onset of numerical abilities observed in shoal-choice tests suggests that training procedures can promote the development of numerical abilities in guppies.

  15. Fermi-Dirac statistics and the number theory

    OpenAIRE

    Kubasiak, A.; Korbicz, J.; Zakrzewski, J.; Lewenstein, M.

    2005-01-01

    We relate the Fermi-Dirac statistics of an ideal Fermi gas in a harmonic trap to partitions of given integers into distinct parts, studied in number theory. Using methods of quantum statistical physics we derive analytic expressions for cumulants of the probability distribution of the number of different partitions.

  16. Large numbers hypothesis. II - Electromagnetic radiation

    Science.gov (United States)

    Adams, P. J.

    1983-01-01

    This paper develops the theory of electromagnetic radiation in the units covariant formalism incorporating Dirac's large numbers hypothesis (LNH). A direct field-to-particle technique is used to obtain the photon propagation equation which explicitly involves the photon replication rate. This replication rate is fixed uniquely by requiring that the form of a free-photon distribution function be preserved, as required by the 2.7 K cosmic radiation. One finds that with this particular photon replication rate the units covariant formalism developed in Paper I actually predicts that the ratio of photon number to proton number in the universe varies as t to the 1/4, precisely in accord with LNH. The cosmological red-shift law is also derived and it is shown to differ considerably from the standard form of (nu)(R) - const.

  17. Working with numbers and statistics a handbook for journalists

    CERN Document Server

    Livingston, Charles

    2005-01-01

    Working With Numbers and Statistics: A Handbook for Journalists will bolster math skills and improve math confidence for journalists at all skill levels. Authors Charles Livingston and Paul Voakes developed this resource book to improve journalist

  18. Modified large number theory with constant G

    International Nuclear Information System (INIS)

    Recami, E.

    1983-01-01

    The inspiring ''numerology'' uncovered by Dirac, Eddington, Weyl, et al. can be explained and derived when it is slightly modified so to connect the ''gravitational world'' (cosmos) with the ''strong world'' (hadron), rather than with the electromagnetic one. The aim of this note is to show the following. In the present approach to the ''Large Number Theory,'' cosmos and hadrons are considered to be (finite) similar systems, so that the ratio R-bar/r-bar of the cosmos typical length R-bar to the hadron typical length r-bar is constant in time (for instance, if both cosmos and hadrons undergo an expansion/contraction cycle: according to the ''cyclical big-bang'' hypothesis: then R-bar and r-bar can be chosen to be the maximum radii, or the average radii). As a consequence, then gravitational constant G results to be independent of time. The present note is based on work done in collaboration with P.Caldirola, G. D. Maccarrone, and M. Pavsic

  19. Hierarchies in Quantum Gravity: Large Numbers, Small Numbers, and Axions

    Science.gov (United States)

    Stout, John Eldon

    Our knowledge of the physical world is mediated by relatively simple, effective descriptions of complex processes. By their very nature, these effective theories obscure any phenomena outside their finite range of validity, discarding information crucial to understanding the full, quantum gravitational theory. However, we may gain enormous insight into the full theory by understanding how effective theories with extreme characteristics--for example, those which realize large-field inflation or have disparate hierarchies of scales--can be naturally realized in consistent theories of quantum gravity. The work in this dissertation focuses on understanding the quantum gravitational constraints on these "extreme" theories in well-controlled corners of string theory. Axion monodromy provides one mechanism for realizing large-field inflation in quantum gravity. These models spontaneously break an axion's discrete shift symmetry and, assuming that the corrections induced by this breaking remain small throughout the excursion, create a long, quasi-flat direction in field space. This weakly-broken shift symmetry has been used to construct a dynamical solution to the Higgs hierarchy problem, dubbed the "relaxion." We study this relaxion mechanism and show that--without major modifications--it can not be naturally embedded within string theory. In particular, we find corrections to the relaxion potential--due to the ten-dimensional backreaction of monodromy charge--that conflict with naive notions of technical naturalness and render the mechanism ineffective. The super-Planckian field displacements necessary for large-field inflation may also be realized via the collective motion of many aligned axions. However, it is not clear that string theory provides the structures necessary for this to occur. We search for these structures by explicitly constructing the leading order potential for C4 axions and computing the maximum possible field displacement in all compactifications of

  20. New feature for an old large number

    International Nuclear Information System (INIS)

    Novello, M.; Oliveira, L.R.A.

    1986-01-01

    A new context for the appearance of the Eddington number (10 39 ), which is due to the examination of elastic scattering of scalar particles (ΠK → ΠK) non-minimally coupled to gravity, is presented. (author) [pt

  1. Negative values of quasidistributions and quantum wave and number statistics

    Science.gov (United States)

    Peřina, J.; Křepelka, J.

    2018-04-01

    We consider nonclassical wave and number quantum statistics, and perform a decomposition of quasidistributions for nonlinear optical down-conversion processes using Bessel functions. We show that negative values of the quasidistribution do not directly represent probabilities; however, they directly influence measurable number statistics. Negative terms in the decomposition related to the nonclassical behavior with negative amplitudes of probability can be interpreted as positive amplitudes of probability in the negative orthogonal Bessel basis, whereas positive amplitudes of probability in the positive basis describe classical cases. However, probabilities are positive in all cases, including negative values of quasidistributions. Negative and positive contributions of decompositions to quasidistributions are estimated. The approach can be adapted to quantum coherence functions.

  2. Statistical processing of large image sequences.

    Science.gov (United States)

    Khellah, F; Fieguth, P; Murray, M J; Allen, M

    2005-01-01

    The dynamic estimation of large-scale stochastic image sequences, as frequently encountered in remote sensing, is important in a variety of scientific applications. However, the size of such images makes conventional dynamic estimation methods, for example, the Kalman and related filters, impractical. In this paper, we present an approach that emulates the Kalman filter, but with considerably reduced computational and storage requirements. Our approach is illustrated in the context of a 512 x 512 image sequence of ocean surface temperature. The static estimation step, the primary contribution here, uses a mixture of stationary models to accurately mimic the effect of a nonstationary prior, simplifying both computational complexity and modeling. Our approach provides an efficient, stable, positive-definite model which is consistent with the given correlation structure. Thus, the methods of this paper may find application in modeling and single-frame estimation.

  3. Improving CASINO performance for models with large number of electrons

    International Nuclear Information System (INIS)

    Anton, L.; Alfe, D.; Hood, R.Q.; Tanqueray, D.

    2009-01-01

    Quantum Monte Carlo calculations have at their core algorithms based on statistical ensembles of multidimensional random walkers which are straightforward to use on parallel computers. Nevertheless some computations have reached the limit of the memory resources for models with more than 1000 electrons because of the need to store a large amount of electronic orbitals related data. Besides that, for systems with large number of electrons, it is interesting to study if the evolution of one configuration of random walkers can be done faster in parallel. We present a comparative study of two ways to solve these problems: (1) distributed orbital data done with MPI or Unix inter-process communication tools, (2) second level parallelism for configuration computation

  4. Low-wave-number statistics of randomly advected passive scalars

    International Nuclear Information System (INIS)

    Kerstein, A.R.; McMurtry, P.A.

    1994-01-01

    A heuristic analysis of the decay of a passive scalar field subject to statistically steady random advection, predicts two low-wave-number spectral scaling regimes analogous to the similarity states previously identified by Chasnov [Phys. Fluids 6, 1036 (1994)]. Consequences of their predicted coexistence in a single flow are examined. The analysis is limited to the idealized case of narrow band advection. To complement the analysis, and to extend the predictions to physically more realistic advection processes, advection diffusion is simulated using a one-dimensional stochastic model. An experimental test of the predictions is proposed

  5. Quantum Statistical Testing of a Quantum Random Number Generator

    Energy Technology Data Exchange (ETDEWEB)

    Humble, Travis S [ORNL

    2014-01-01

    The unobservable elements in a quantum technology, e.g., the quantum state, complicate system verification against promised behavior. Using model-based system engineering, we present methods for verifying the opera- tion of a prototypical quantum random number generator. We begin with the algorithmic design of the QRNG followed by the synthesis of its physical design requirements. We next discuss how quantum statistical testing can be used to verify device behavior as well as detect device bias. We conclude by highlighting how system design and verification methods must influence effort to certify future quantum technologies.

  6. Statistical fluctuations of the number of neutrons in a pile

    International Nuclear Information System (INIS)

    Raievski, V.

    1958-01-01

    The theory of the statistical fluctuations in a pile is extended to the space dependent case, and gives the fluctuations of the number of neutrons in a cell of the core or reflector of the pile. This number changes through elementary processes occurring at random, which are, capture, source, fission and scattering. Of all these processes, fission is the only one which changes more than one neutron at a time and so is responsible of the deviation of the fluctuations from a Poisson law. The importance of this deviation depends on the dimensions of the cell compared to the slowing down length. When the dimensions are small, the fluctuations close to a Poisson law. (author) [fr

  7. Some Statistics for Measuring Large-Scale Structure

    OpenAIRE

    Brandenberger, Robert H.; Kaplan, David M.; A, Stephen; Ramsey

    1993-01-01

    Good statistics for measuring large-scale structure in the Universe must be able to distinguish between different models of structure formation. In this paper, two and three dimensional ``counts in cell" statistics and a new ``discrete genus statistic" are applied to toy versions of several popular theories of structure formation: random phase cold dark matter model, cosmic string models, and global texture scenario. All three statistics appear quite promising in terms of differentiating betw...

  8. Alberta oil and gas industry: Annual statistics for 1997. Statistical series number 98-17

    International Nuclear Information System (INIS)

    1998-01-01

    This document presents annual statistics for the Alberta oil and gas industry for the supply and disposition of crude oil and equivalent; gas; ethane; propane; butanes; NGL mixes; and sulfur. Figures are given for deliveries and prices for the current year and also historically (1987--1996). Figures are also provided for the number of wells drilled during the year, meters drilled, and the annual well count

  9. Small-number statistics near the clustering transition in a compartementalized granular gas

    NARCIS (Netherlands)

    Mikkelsen, René; van der Weele, Ko; van der Meer, Devaraj; van Hecke, Martin; Lohse, Detlef

    2005-01-01

    Statistical fluctuations are observed to profoundly influence the clustering behavior of granular material in a vibrated system consisting of two connected compartments. When the number of particles N is sufficiently large sN<300 is sufficientd, the clustering follows the lines of a standard

  10. A reanalysis of Lord's statistical treatment of football numbers

    NARCIS (Netherlands)

    Zand Scholten, A.; Borsboom, D.

    2009-01-01

    Stevens’ theory of admissible statistics [Stevens, S. S. (1946). On the theory of scales of measurement. Science, 103, 677680] states that measurement levels should guide the choice of statistical test, such that the truth value of statements based on a statistical analysis remains invariant under

  11. Streamline segment statistics of premixed flames with nonunity Lewis numbers

    Science.gov (United States)

    Chakraborty, Nilanjan; Wang, Lipo; Klein, Markus

    2014-03-01

    The interaction of flame and surrounding fluid motion is of central importance in the fundamental understanding of turbulent combustion. It is demonstrated here that this interaction can be represented using streamline segment analysis, which was previously applied in nonreactive turbulence. The present work focuses on the effects of the global Lewis number (Le) on streamline segment statistics in premixed flames in the thin-reaction-zones regime. A direct numerical simulation database of freely propagating thin-reaction-zones regime flames with Le ranging from 0.34 to 1.2 is used to demonstrate that Le has significant influences on the characteristic features of the streamline segment, such as the curve length, the difference in the velocity magnitude at two extremal points, and their correlations with the local flame curvature. The strengthenings of the dilatation rate, flame normal acceleration, and flame-generated turbulence with decreasing Le are principally responsible for these observed effects. An expression for the probability density function (pdf) of the streamline segment length, originally developed for nonreacting turbulent flows, captures the qualitative behavior for turbulent premixed flames in the thin-reaction-zones regime for a wide range of Le values. The joint pdfs between the streamline length and the difference in the velocity magnitude at two extremal points for both unweighted and density-weighted velocity vectors are analyzed and compared. Detailed explanations are provided for the observed differences in the topological behaviors of the streamline segment in response to the global Le.

  12. Polish Phoneme Statistics Obtained On Large Set Of Written Texts

    Directory of Open Access Journals (Sweden)

    Bartosz Ziółko

    2009-01-01

    Full Text Available The phonetical statistics were collected from several Polish corpora. The paper is a summaryof the data which are phoneme n-grams and some phenomena in the statistics. Triphonestatistics apply context-dependent speech units which have an important role in speech recognitionsystems and were never calculated for a large set of Polish written texts. The standardphonetic alphabet for Polish, SAMPA, and methods of providing phonetic transcriptions are described.

  13. Multivariate statistics high-dimensional and large-sample approximations

    CERN Document Server

    Fujikoshi, Yasunori; Shimizu, Ryoichi

    2010-01-01

    A comprehensive examination of high-dimensional analysis of multivariate methods and their real-world applications Multivariate Statistics: High-Dimensional and Large-Sample Approximations is the first book of its kind to explore how classical multivariate methods can be revised and used in place of conventional statistical tools. Written by prominent researchers in the field, the book focuses on high-dimensional and large-scale approximations and details the many basic multivariate methods used to achieve high levels of accuracy. The authors begin with a fundamental presentation of the basic

  14. Thermocapillary Bubble Migration: Thermal Boundary Layers for Large Marangoni Numbers

    Science.gov (United States)

    Balasubramaniam, R.; Subramanian, R. S.

    1996-01-01

    The migration of an isolated gas bubble in an immiscible liquid possessing a temperature gradient is analyzed in the absence of gravity. The driving force for the bubble motion is the shear stress at the interface which is a consequence of the temperature dependence of the surface tension. The analysis is performed under conditions for which the Marangoni number is large, i.e. energy is transferred predominantly by convection. Velocity fields in the limit of both small and large Reynolds numbers are used. The thermal problem is treated by standard boundary layer theory. The outer temperature field is obtained in the vicinity of the bubble. A similarity solution is obtained for the inner temperature field. For both small and large Reynolds numbers, the asymptotic values of the scaled migration velocity of the bubble in the limit of large Marangoni numbers are calculated. The results show that the migration velocity has the same scaling for both low and large Reynolds numbers, but with a different coefficient. Higher order thermal boundary layers are analyzed for the large Reynolds number flow field and the higher order corrections to the migration velocity are obtained. Results are also presented for the momentum boundary layer and the thermal wake behind the bubble, for large Reynolds number conditions.

  15. Crunching Numbers: What Cancer Screening Statistics Really Tell Us

    Science.gov (United States)

    Cancer screening studies have shown that more screening does not necessarily translate into fewer cancer deaths. This article explains how to interpret the statistics used to describe the results of screening studies.

  16. On a strong law of large numbers for monotone measures

    Czech Academy of Sciences Publication Activity Database

    Agahi, H.; Mohammadpour, A.; Mesiar, Radko; Ouyang, Y.

    2013-01-01

    Roč. 83, č. 4 (2013), s. 1213-1218 ISSN 0167-7152 R&D Projects: GA ČR GAP402/11/0378 Institutional support: RVO:67985556 Keywords : capacity * Choquet integral * strong law of large numbers Subject RIV: BA - General Mathematics Impact factor: 0.531, year: 2013 http://library.utia.cas.cz/separaty/2013/E/mesiar-on a strong law of large numbers for monotone measures.pdf

  17. Shell model in large spaces and statistical spectroscopy

    International Nuclear Information System (INIS)

    Kota, V.K.B.

    1996-01-01

    For many nuclear structure problems of current interest it is essential to deal with shell model in large spaces. For this, three different approaches are now in use and two of them are: (i) the conventional shell model diagonalization approach but taking into account new advances in computer technology; (ii) the shell model Monte Carlo method. A brief overview of these two methods is given. Large space shell model studies raise fundamental questions regarding the information content of the shell model spectrum of complex nuclei. This led to the third approach- the statistical spectroscopy methods. The principles of statistical spectroscopy have their basis in nuclear quantum chaos and they are described (which are substantiated by large scale shell model calculations) in some detail. (author)

  18. USA by Numbers: A Statistical Portrait of the United States.

    Science.gov (United States)

    Weber, Susan, Ed.

    This book presents demographic data about a variety of U.S. public policies, social problems, and environmental issues. The issues and problems that the statistics illustrate (such as overflowing garbage dumps, homelessness, child poverty, and smog and water pollution) are connected with, and the consequences of, the expanding U.S. population. The…

  19. A Chain Perspective on Large-scale Number Systems

    NARCIS (Netherlands)

    Grijpink, J.H.A.M.

    2012-01-01

    As large-scale number systems gain significance in social and economic life (electronic communication, remote electronic authentication), the correct functioning and the integrity of public number systems take on crucial importance. They are needed to uniquely indicate people, objects or phenomena

  20. Playing the Numbers: The spurious promise of global trafficking statistics

    Directory of Open Access Journals (Sweden)

    David A. Feingold

    2017-04-01

    Full Text Available ‘Playing the numbers,’ ‘the numbers game,’ ‘the policy racket’: for those unfamiliar with American illegal lotteries and some of the legendary gangsters like Bumpy Johnson and Dutch Schultz that turned them into a major revenue stream for organised crime that still flourishes today, the concept was simple. The odds were disproportionately long, but poor people could bet very small amounts. It was, as they used to say, ‘a mugs game’; the organisers did well, while the poor lived on hope.

  1. Statistics of LES simulations of large wind farms

    DEFF Research Database (Denmark)

    Andersen, Søren Juhl; Sørensen, Jens Nørkær; Mikkelsen, Robert Flemming

    2016-01-01

    . The statistical moments appear to collapse and hence the turbulence inside large wind farms can potentially be scaled accordingly. The thrust coefficient is estimated by two different reference velocities and the generic CT expression by Frandsen. A reference velocity derived from the power production is shown...... to give very good agreement and furthermore enables the very good estimation of the thrust force using only the steady CT-curve, even for very short time samples. Finally, the effective turbulence inside large wind farms and the equivalent loads are examined....

  2. United States Air Force Statistical Digest 1947, Second Annual Number

    Science.gov (United States)

    1948-08-01

    Type and Series--Number Inetalled and Status of spere Enginell: lIlar 1944 to Dec 1947•••• ;, ••••••••••••••••••••••••• Tabla 99.-- Se!.o~ed Aircraft

  3. The large numbers hypothesis and a relativistic theory of gravitation

    International Nuclear Information System (INIS)

    Lau, Y.K.; Prokhovnik, S.J.

    1986-01-01

    A way to reconcile Dirac's large numbers hypothesis and Einstein's theory of gravitation was recently suggested by Lau (1985). It is characterized by the conjecture of a time-dependent cosmological term and gravitational term in Einstein's field equations. Motivated by this conjecture and the large numbers hypothesis, we formulate here a scalar-tensor theory in terms of an action principle. The cosmological term is required to be spatially dependent as well as time dependent in general. The theory developed is appled to a cosmological model compatible with the large numbers hypothesis. The time-dependent form of the cosmological term and the scalar potential are then deduced. A possible explanation of the smallness of the cosmological term is also given and the possible significance of the scalar field is speculated

  4. Fatal crashes involving large numbers of vehicles and weather.

    Science.gov (United States)

    Wang, Ying; Liang, Liming; Evans, Leonard

    2017-12-01

    Adverse weather has been recognized as a significant threat to traffic safety. However, relationships between fatal crashes involving large numbers of vehicles and weather are rarely studied according to the low occurrence of crashes involving large numbers of vehicles. By using all 1,513,792 fatal crashes in the Fatality Analysis Reporting System (FARS) data, 1975-2014, we successfully described these relationships. We found: (a) fatal crashes involving more than 35 vehicles are most likely to occur in snow or fog; (b) fatal crashes in rain are three times as likely to involve 10 or more vehicles as fatal crashes in good weather; (c) fatal crashes in snow [or fog] are 24 times [35 times] as likely to involve 10 or more vehicles as fatal crashes in good weather. If the example had used 20 vehicles, the risk ratios would be 6 for rain, 158 for snow, and 171 for fog. To reduce the risk of involvement in fatal crashes with large numbers of vehicles, drivers should slow down more than they currently do under adverse weather conditions. Driver deaths per fatal crash increase slowly with increasing numbers of involved vehicles when it is snowing or raining, but more steeply when clear or foggy. We conclude that in order to reduce risk of involvement in crashes involving large numbers of vehicles, drivers must reduce speed in fog, and in snow or rain, reduce speed by even more than they already do. Copyright © 2017 National Safety Council and Elsevier Ltd. All rights reserved.

  5. Statistical evaluation of PACSTAT random number generation capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, G.F.; Toland, M.R.; Harty, H.; Budden, M.J.; Bartley, C.L.

    1988-05-01

    This report summarizes the work performed in verifying the general purpose Monte Carlo driver-program PACSTAT. The main objective of the work was to verify the performance of PACSTAT's random number generation capabilities. Secondary objectives were to document (using controlled configuration management procedures) changes made in PACSTAT at Pacific Northwest Laboratory, and to assure that PACSTAT input and output files satisfy quality assurance traceability constraints. Upon receipt of the PRIME version of the PACSTAT code from the Basalt Waste Isolation Project, Pacific Northwest Laboratory staff converted the code to run on Digital Equipment Corporation (DEC) VAXs. The modifications to PACSTAT were implemented using the WITNESS configuration management system, with the modifications themselves intended to make the code as portable as possible. Certain modifications were made to make the PACSTAT input and output files conform to quality assurance traceability constraints. 10 refs., 17 figs., 6 tabs.

  6. On Independence for Capacities with Law of Large Numbers

    OpenAIRE

    Huang, Weihuan

    2017-01-01

    This paper introduces new notions of Fubini independence and Exponential independence of random variables under capacities to fit Ellsberg's model, and finds out the relationships between Fubini independence, Exponential independence, MacCheroni and Marinacci's independence and Peng's independence. As an application, we give a weak law of large numbers for capacities under Exponential independence.

  7. Teaching Multiplication of Large Positive Whole Numbers Using ...

    African Journals Online (AJOL)

    This study investigated the teaching of multiplication of large positive whole numbers using the grating method and the effect of this method on students' performance in junior secondary schools. The study was conducted in Obio Akpor Local Government Area of Rivers state. It was quasi- experimental. Two research ...

  8. Lovelock inflation and the number of large dimensions

    CERN Document Server

    Ferrer, Francesc

    2007-01-01

    We discuss an inflationary scenario based on Lovelock terms. These higher order curvature terms can lead to inflation when there are more than three spatial dimensions. Inflation will end if the extra dimensions are stabilised, so that at most three dimensions are free to expand. This relates graceful exit to the number of large dimensions.

  9. Gene coexpression measures in large heterogeneous samples using count statistics.

    Science.gov (United States)

    Wang, Y X Rachel; Waterman, Michael S; Huang, Haiyan

    2014-11-18

    With the advent of high-throughput technologies making large-scale gene expression data readily available, developing appropriate computational tools to process these data and distill insights into systems biology has been an important part of the "big data" challenge. Gene coexpression is one of the earliest techniques developed that is still widely in use for functional annotation, pathway analysis, and, most importantly, the reconstruction of gene regulatory networks, based on gene expression data. However, most coexpression measures do not specifically account for local features in expression profiles. For example, it is very likely that the patterns of gene association may change or only exist in a subset of the samples, especially when the samples are pooled from a range of experiments. We propose two new gene coexpression statistics based on counting local patterns of gene expression ranks to take into account the potentially diverse nature of gene interactions. In particular, one of our statistics is designed for time-course data with local dependence structures, such as time series coupled over a subregion of the time domain. We provide asymptotic analysis of their distributions and power, and evaluate their performance against a wide range of existing coexpression measures on simulated and real data. Our new statistics are fast to compute, robust against outliers, and show comparable and often better general performance.

  10. Extreme value statistics and thermodynamics of earthquakes: large earthquakes

    Directory of Open Access Journals (Sweden)

    B. H. Lavenda

    2000-06-01

    Full Text Available A compound Poisson process is used to derive a new shape parameter which can be used to discriminate between large earthquakes and aftershock sequences. Sample exceedance distributions of large earthquakes are fitted to the Pareto tail and the actual distribution of the maximum to the Fréchet distribution, while the sample distribution of aftershocks are fitted to a Beta distribution and the distribution of the minimum to the Weibull distribution for the smallest value. The transition between initial sample distributions and asymptotic extreme value distributions shows that self-similar power laws are transformed into nonscaling exponential distributions so that neither self-similarity nor the Gutenberg-Richter law can be considered universal. The energy-magnitude transformation converts the Fréchet distribution into the Gumbel distribution, originally proposed by Epstein and Lomnitz, and not the Gompertz distribution as in the Lomnitz-Adler and Lomnitz generalization of the Gutenberg-Richter law. Numerical comparison is made with the Lomnitz-Adler and Lomnitz analysis using the same Catalogue of Chinese Earthquakes. An analogy is drawn between large earthquakes and high energy particle physics. A generalized equation of state is used to transform the Gamma density into the order-statistic Fréchet distribution. Earthquaketemperature and volume are determined as functions of the energy. Large insurance claims based on the Pareto distribution, which does not have a right endpoint, show why there cannot be a maximum earthquake energy.

  11. Extreme value statistics and thermodynamics of earthquakes. Large earthquakes

    Energy Technology Data Exchange (ETDEWEB)

    Lavenda, B. [Camerino Univ., Camerino, MC (Italy); Cipollone, E. [ENEA, Centro Ricerche Casaccia, S. Maria di Galeria, RM (Italy). National Centre for Research on Thermodynamics

    2000-06-01

    A compound Poisson process is used to derive a new shape parameter which can be used to discriminate between large earthquakes and aftershocks sequences. Sample exceedance distributions of large earthquakes are fitted to the Pareto tail and the actual distribution of the maximum to the Frechet distribution, while the sample distribution of aftershocks are fitted to a Beta distribution and the distribution of the minimum to the Weibull distribution for the smallest value. The transition between initial sample distributions and asymptotic extreme value distributions show that self-similar power laws are transformed into non scaling exponential distributions so that neither self-similarity nor the Gutenberg-Richter law can be considered universal. The energy-magnitude transformation converts the Frechet distribution into the Gumbel distribution, originally proposed by Epstein and Lomnitz, and not the Gompertz distribution as in the Lomnitz-Adler and Lomnitz generalization of the Gutenberg-Richter law. Numerical comparison is made with the Lomnitz-Adler and Lomnitz analysis using the same catalogue of Chinese earthquakes. An analogy is drawn between large earthquakes and high energy particle physics. A generalized equation of state is used to transform the Gamma density into the order-statistic Frechet distribution. Earthquake temperature and volume are determined as functions of the energy. Large insurance claims based on the Pareto distribution, which does not have a right endpoint, show why there cannot be a maximum earthquake energy.

  12. Statistical measurement of power spectrum density of large aperture optical component

    International Nuclear Information System (INIS)

    Xu Jiancheng; Xu Qiao; Chai Liqun

    2010-01-01

    According to the requirement of ICF, a method based on statistical theory has been proposed to measure the power spectrum density (PSD) of large aperture optical components. The method breaks the large-aperture wavefront into small regions, and obtains the PSD of the large-aperture wavefront by weighted averaging of the PSDs of the regions, where the weight factor is each region's area. Simulation and experiment demonstrate the effectiveness of the proposed method. They also show that, the obtained PSDs of the large-aperture wavefront by statistical method and sub-aperture stitching method fit well, when the number of small regions is no less than 8 x 8. The statistical method is not sensitive to translation stage's errors and environment instabilities, thus it is appropriate for PSD measurement during the process of optical fabrication. (authors)

  13. A large number of stepping motor network construction by PLC

    Science.gov (United States)

    Mei, Lin; Zhang, Kai; Hongqiang, Guo

    2017-11-01

    In the flexible automatic line, the equipment is complex, the control mode is flexible, how to realize the large number of step and servo motor information interaction, the orderly control become a difficult control. Based on the existing flexible production line, this paper makes a comparative study of its network strategy. After research, an Ethernet + PROFIBUSE communication configuration based on PROFINET IO and profibus was proposed, which can effectively improve the data interaction efficiency of the equipment and stable data interaction information.

  14. Fluid Mechanics of Aquatic Locomotion at Large Reynolds Numbers

    OpenAIRE

    Govardhan, RN; Arakeri, JH

    2011-01-01

    Abstract | There exist a huge range of fish species besides other aquatic organisms like squids and salps that locomote in water at large Reynolds numbers, a regime of flow where inertial forces dominate viscous forces. In the present review, we discuss the fluid mechanics governing the locomotion of such organisms. Most fishes propel themselves by periodic undulatory motions of the body and tail, and the typical classification of their swimming modes is based on the fraction of their body...

  15. Rotating thermal convection at very large Rayleigh numbers

    Science.gov (United States)

    Weiss, Stephan; van Gils, Dennis; Ahlers, Guenter; Bodenschatz, Eberhard

    2016-11-01

    The large scale thermal convection systems in geo- and astrophysics are usually influenced by Coriolis forces caused by the rotation of their celestial bodies. To better understand the influence of rotation on the convective flow field and the heat transport at these conditions, we study Rayleigh-Bénard convection, using pressurized sulfur hexaflouride (SF6) at up to 19 bars in a cylinder of diameter D=1.12 m and a height of L=2.24 m. The gas is heated from below and cooled from above and the convection cell sits on a rotating table inside a large pressure vessel (the "Uboot of Göttingen"). With this setup Rayleigh numbers of up to Ra =1015 can be reached, while Ekman numbers as low as Ek =10-8 are possible. The Prandtl number in these experiment is kept constant at Pr = 0 . 8 . We report on heat flux measurements (expressed by the Nusselt number Nu) as well as measurements from more than 150 temperature probes inside the flow. We thank the Deutsche Forschungsgemeinschaft (DFG) for financial support through SFB963: "Astrophysical Flow Instabilities and Turbulence". The work of GA was supported in part by the US National Science Foundation through Grant DMR11-58514.

  16. Lepton number violation in theories with a large number of standard model copies

    International Nuclear Information System (INIS)

    Kovalenko, Sergey; Schmidt, Ivan; Paes, Heinrich

    2011-01-01

    We examine lepton number violation (LNV) in theories with a saturated black hole bound on a large number of species. Such theories have been advocated recently as a possible solution to the hierarchy problem and an explanation of the smallness of neutrino masses. On the other hand, the violation of the lepton number can be a potential phenomenological problem of this N-copy extension of the standard model as due to the low quantum gravity scale black holes may induce TeV scale LNV operators generating unacceptably large rates of LNV processes. We show, however, that this issue can be avoided by introducing a spontaneously broken U 1(B-L) . Then, due to the existence of a specific compensation mechanism between contributions of different Majorana neutrino states, LNV processes in the standard model copy become extremely suppressed with rates far beyond experimental reach.

  17. Statistically and Computationally Efficient Estimating Equations for Large Spatial Datasets

    KAUST Repository

    Sun, Ying

    2014-11-07

    For Gaussian process models, likelihood based methods are often difficult to use with large irregularly spaced spatial datasets, because exact calculations of the likelihood for n observations require O(n3) operations and O(n2) memory. Various approximation methods have been developed to address the computational difficulties. In this paper, we propose new unbiased estimating equations based on score equation approximations that are both computationally and statistically efficient. We replace the inverse covariance matrix that appears in the score equations by a sparse matrix to approximate the quadratic forms, then set the resulting quadratic forms equal to their expected values to obtain unbiased estimating equations. The sparse matrix is constructed by a sparse inverse Cholesky approach to approximate the inverse covariance matrix. The statistical efficiency of the resulting unbiased estimating equations are evaluated both in theory and by numerical studies. Our methods are applied to nearly 90,000 satellite-based measurements of water vapor levels over a region in the Southeast Pacific Ocean.

  18. Statistically and Computationally Efficient Estimating Equations for Large Spatial Datasets

    KAUST Repository

    Sun, Ying; Stein, Michael L.

    2014-01-01

    For Gaussian process models, likelihood based methods are often difficult to use with large irregularly spaced spatial datasets, because exact calculations of the likelihood for n observations require O(n3) operations and O(n2) memory. Various approximation methods have been developed to address the computational difficulties. In this paper, we propose new unbiased estimating equations based on score equation approximations that are both computationally and statistically efficient. We replace the inverse covariance matrix that appears in the score equations by a sparse matrix to approximate the quadratic forms, then set the resulting quadratic forms equal to their expected values to obtain unbiased estimating equations. The sparse matrix is constructed by a sparse inverse Cholesky approach to approximate the inverse covariance matrix. The statistical efficiency of the resulting unbiased estimating equations are evaluated both in theory and by numerical studies. Our methods are applied to nearly 90,000 satellite-based measurements of water vapor levels over a region in the Southeast Pacific Ocean.

  19. Efficient Partitioning of Large Databases without Query Statistics

    Directory of Open Access Journals (Sweden)

    Shahidul Islam KHAN

    2016-11-01

    Full Text Available An efficient way of improving the performance of a database management system is distributed processing. Distribution of data involves fragmentation or partitioning, replication, and allocation process. Previous research works provided partitioning based on empirical data about the type and frequency of the queries. These solutions are not suitable at the initial stage of a distributed database as query statistics are not available then. In this paper, I have presented a fragmentation technique, Matrix based Fragmentation (MMF, which can be applied at the initial stage as well as at later stages of distributed databases. Instead of using empirical data, I have developed a matrix, Modified Create, Read, Update and Delete (MCRUD, to partition a large database properly. Allocation of fragments is done simultaneously in my proposed technique. So using MMF, no additional complexity is added for allocating the fragments to the sites of a distributed database as fragmentation is synchronized with allocation. The performance of a DDBMS can be improved significantly by avoiding frequent remote access and high data transfer among the sites. Results show that proposed technique can solve the initial partitioning problem of large distributed databases.

  20. [Dual process in large number estimation under uncertainty].

    Science.gov (United States)

    Matsumuro, Miki; Miwa, Kazuhisa; Terai, Hitoshi; Yamada, Kento

    2016-08-01

    According to dual process theory, there are two systems in the mind: an intuitive and automatic System 1 and a logical and effortful System 2. While many previous studies about number estimation have focused on simple heuristics and automatic processes, the deliberative System 2 process has not been sufficiently studied. This study focused on the System 2 process for large number estimation. First, we described an estimation process based on participants’ verbal reports. The task, corresponding to the problem-solving process, consisted of creating subgoals, retrieving values, and applying operations. Second, we investigated the influence of such deliberative process by System 2 on intuitive estimation by System 1, using anchoring effects. The results of the experiment showed that the System 2 process could mitigate anchoring effects.

  1. The large number hypothesis and Einstein's theory of gravitation

    International Nuclear Information System (INIS)

    Yun-Kau Lau

    1985-01-01

    In an attempt to reconcile the large number hypothesis (LNH) with Einstein's theory of gravitation, a tentative generalization of Einstein's field equations with time-dependent cosmological and gravitational constants is proposed. A cosmological model consistent with the LNH is deduced. The coupling formula of the cosmological constant with matter is found, and as a consequence, the time-dependent formulae of the cosmological constant and the mean matter density of the Universe at the present epoch are then found. Einstein's theory of gravitation, whether with a zero or nonzero cosmological constant, becomes a limiting case of the new generalized field equations after the early epoch

  2. Combining large number of weak biomarkers based on AUC.

    Science.gov (United States)

    Yan, Li; Tian, Lili; Liu, Song

    2015-12-20

    Combining multiple biomarkers to improve diagnosis and/or prognosis accuracy is a common practice in clinical medicine. Both parametric and non-parametric methods have been developed for finding the optimal linear combination of biomarkers to maximize the area under the receiver operating characteristic curve (AUC), primarily focusing on the setting with a small number of well-defined biomarkers. This problem becomes more challenging when the number of observations is not order of magnitude greater than the number of variables, especially when the involved biomarkers are relatively weak. Such settings are not uncommon in certain applied fields. The first aim of this paper is to empirically evaluate the performance of existing linear combination methods under such settings. The second aim is to propose a new combination method, namely, the pairwise approach, to maximize AUC. Our simulation studies demonstrated that the performance of several existing methods can become unsatisfactory as the number of markers becomes large, while the newly proposed pairwise method performs reasonably well. Furthermore, we apply all the combination methods to real datasets used for the development and validation of MammaPrint. The implication of our study for the design of optimal linear combination methods is discussed. Copyright © 2015 John Wiley & Sons, Ltd.

  3. Quasi-isodynamic configuration with large number of periods

    International Nuclear Information System (INIS)

    Shafranov, V.D.; Isaev, M.Yu.; Mikhailov, M.I.; Subbotin, A.A.; Cooper, W.A.; Kalyuzhnyj, V.N.; Kasilov, S.V.; Nemov, V.V.; Kernbichler, W.; Nuehrenberg, C.; Nuehrenberg, J.; Zille, R.

    2005-01-01

    It has been previously reported that quasi-isodynamic (qi) stellarators with poloidal direction of the contours of B on magnetic surface can exhibit very good fast- particle collisionless confinement. In addition, approaching the quasi-isodynamicity condition leads to diminished neoclassical transport and small bootstrap current. The calculations of local-mode stability show that there is a tendency toward an increasing beta limit with increasing number of periods. The consideration of the quasi-helically symmetric systems has demonstrated that with increasing aspect ratio (and number of periods) the optimized configuration approaches the straight symmetric counterpart, for which the optimal parameters and highest beta values were found by optimization of the boundary magnetic surface cross-section. The qi system considered here with zero net toroidal current do not have a symmetric analogue in the limit of large aspect ratio and finite rotational transform. Thus, it is not clear whether some invariant structure of the configuration period exists in the limit of negligible toroidal effect and what are the best possible parameters for it. In the present paper the results of an optimization of the configuration with N = 12 number of periods are presented. Such properties as fast-particle confinement, effective ripple, structural factor of bootstrap current and MHD stability are considered. It is shown that MHD stability limit here is larger than in configurations with smaller number of periods considered earlier. Nevertheless, the toroidal effect in this configuration is still significant so that a simple increase of the number of periods and proportional growth of aspect ratio do not conserve favourable neoclassical transport and ideal local-mode stability properties. (author)

  4. Automatic trajectory measurement of large numbers of crowded objects

    Science.gov (United States)

    Li, Hui; Liu, Ye; Chen, Yan Qiu

    2013-06-01

    Complex motion patterns of natural systems, such as fish schools, bird flocks, and cell groups, have attracted great attention from scientists for years. Trajectory measurement of individuals is vital for quantitative and high-throughput study of their collective behaviors. However, such data are rare mainly due to the challenges of detection and tracking of large numbers of objects with similar visual features and frequent occlusions. We present an automatic and effective framework to measure trajectories of large numbers of crowded oval-shaped objects, such as fish and cells. We first use a novel dual ellipse locator to detect the coarse position of each individual and then propose a variance minimization active contour method to obtain the optimal segmentation results. For tracking, cost matrix of assignment between consecutive frames is trainable via a random forest classifier with many spatial, texture, and shape features. The optimal trajectories are found for the whole image sequence by solving two linear assignment problems. We evaluate the proposed method on many challenging data sets.

  5. Matthew Crabbe, Myth-Busting China's Numbers: Understandig and Using China's Statistics

    DEFF Research Database (Denmark)

    Grünberg, Nis

    2014-01-01

    Book review of: Matthew Crabbe: Myth-Busting China's Numbers: Understandig and Using China's Statistics. Houndmills, Basingstoke: Palgrave Macmillan, 2014. 268 pp.......Book review of: Matthew Crabbe: Myth-Busting China's Numbers: Understandig and Using China's Statistics. Houndmills, Basingstoke: Palgrave Macmillan, 2014. 268 pp....

  6. Numerical reconstruction of photon-number statistics from photocounting statistics: Regularization of an ill-posed problem

    International Nuclear Information System (INIS)

    Starkov, V. N.; Semenov, A. A.; Gomonay, H. V.

    2009-01-01

    We demonstrate a practical possibility of loss compensation in measured photocounting statistics in the presence of dark counts and background radiation noise. It is shown that satisfactory results are obtained even in the case of low detection efficiency and large experimental errors.

  7. The large numbers hypothesis and the Einstein theory of gravitation

    International Nuclear Information System (INIS)

    Dirac, P.A.M.

    1979-01-01

    A study of the relations between large dimensionless numbers leads to the belief that G, expressed in atomic units, varies with the epoch while the Einstein theory requires G to be constant. These two requirements can be reconciled by supposing that the Einstein theory applies with a metric that differs from the atomic metric. The theory can be developed with conservation of mass by supposing that the continual increase in the mass of the observable universe arises from a continual slowing down of the velocity of recession of the galaxies. This leads to a model of the Universe that was first proposed by Einstein and de Sitter (the E.S. model). The observations of the microwave radiation fit in with this model. The static Schwarzchild metric has to be modified to fit in with the E.S. model for large r. The modification is worked out, and also the motion of planets with the new metric. It is found that there is a difference between ephemeris time and atomic time, and also that there should be an inward spiralling of the planets, referred to atomic units, superposed on the motion given by ordinary gravitational theory. These are effects that can be checked by observation, but there is no conclusive evidence up to the present. (author)

  8. A Characterization of Hypergraphs with Large Domination Number

    Directory of Open Access Journals (Sweden)

    Henning Michael A.

    2016-05-01

    Full Text Available Let H = (V, E be a hypergraph with vertex set V and edge set E. A dominating set in H is a subset of vertices D ⊆ V such that for every vertex v ∈ V \\ D there exists an edge e ∈ E for which v ∈ e and e ∩ D ≠ ∅. The domination number γ(H is the minimum cardinality of a dominating set in H. It is known [Cs. Bujtás, M.A. Henning and Zs. Tuza, Transversals and domination in uniform hypergraphs, European J. Combin. 33 (2012 62-71] that for k ≥ 5, if H is a hypergraph of order n and size m with all edges of size at least k and with no isolated vertex, then γ(H ≤ (n + ⌊(k − 3/2⌋m/(⌊3(k − 1/2⌋. In this paper, we apply a recent result of the authors on hypergraphs with large transversal number [M.A. Henning and C. Löwenstein, A characterization of hypergraphs that achieve equality in the Chvátal-McDiarmid Theorem, Discrete Math. 323 (2014 69-75] to characterize the hypergraphs achieving equality in this bound.

  9. Comparing Data Sets: Implicit Summaries of the Statistical Properties of Number Sets

    Science.gov (United States)

    Morris, Bradley J.; Masnick, Amy M.

    2015-01-01

    Comparing datasets, that is, sets of numbers in context, is a critical skill in higher order cognition. Although much is known about how people compare single numbers, little is known about how number sets are represented and compared. We investigated how subjects compared datasets that varied in their statistical properties, including ratio of…

  10. Particle creation and Dirac's large number hypothesis; and Reply

    International Nuclear Information System (INIS)

    Canuto, V.; Adams, P.J.; Hsieh, S.H.; Tsiang, E.; Steigman, G.

    1976-01-01

    The claim made by Steigman (Nature; 261:479 (1976)), that the creation of matter as postulated by Dirac (Proc. R. Soc.; A338:439 (1974)) is unnecessary, is here shown to be incorrect. It is stated that Steigman's claim that Dirac's large Number Hypothesis (LNH) does not require particle creation is wrong because he has assumed that which he was seeking to prove, that is that rho does not contain matter creation. Steigman's claim that Dirac's LNH leads to nonsensical results in the very early Universe is superficially correct, but this only supports Dirac's contention that the LNH may not be valid in the very early Universe. In a reply Steigman points out that in Dirac's original cosmology R approximately tsup(1/3) and using this model the results and conclusions of the present author's paper do apply but using a variation chosen by Canuto et al (T approximately t) Dirac's LNH cannot apply. Additionally it is observed that a cosmological theory which only predicts the present epoch is of questionable value. (U.K.)

  11. A modified large number theory with constant G

    Science.gov (United States)

    Recami, Erasmo

    1983-03-01

    The inspiring “numerology” uncovered by Dirac, Eddington, Weyl, et al. can be explained and derived when it is slightly modified so to connect the “gravitational world” (cosmos) with the “strong world” (hadron), rather than with the electromagnetic one. The aim of this note is to show the following. In the present approach to the “Large Number Theory,” cosmos and hadrons are considered to be (finite) similar systems, so that the ratio{{bar R} / {{bar R} {bar r}} of the cosmos typical lengthbar R to the hadron typical lengthbar r is constant in time (for instance, if both cosmos and hadrons undergo an expansion/contraction cycle—according to the “cyclical bigbang” hypothesis—thenbar R andbar r can be chosen to be the maximum radii, or the average radii). As a consequence, then gravitational constant G results to be independent of time. The present note is based on work done in collaboration with P. Caldirola, G. D. Maccarrone, and M. Pavšič.

  12. Limiting values of large deviation probabilities of quadratic statistics

    NARCIS (Netherlands)

    Jeurnink, Gerardus A.M.; Kallenberg, W.C.M.

    1990-01-01

    Application of exact Bahadur efficiencies in testing theory or exact inaccuracy rates in estimation theory needs evaluation of large deviation probabilities. Because of the complexity of the expressions, frequently a local limit of the nonlocal measure is considered. Local limits of large deviation

  13. Generalized statistical convergence of order β for sequences of fuzzy numbers

    Science.gov (United States)

    Altınok, Hıfsı; Karakaş, Abdulkadir; Altın, Yavuz

    2018-01-01

    In the present paper, we introduce the concepts of Δm-statistical convergence of order β for sequences of fuzzy numbers and strongly Δm-summable of order β for sequences of fuzzy numbers by using a modulus function f and taking supremum on metric d for 0 < β ≤ 1 and give some inclusion relations between them.

  14. The large lungs of elite swimmers: an increased alveolar number?

    Science.gov (United States)

    Armour, J; Donnelly, P M; Bye, P T

    1993-02-01

    In order to obtain further insight into the mechanisms relating to the large lung volumes of swimmers, tests of mechanical lung function, including lung distensibility (K) and elastic recoil, pulmonary diffusion capacity, and respiratory mouth pressures, together with anthropometric data (height, weight, body surface area, chest width, depth and surface area), were compared in eight elite male swimmers, eight elite male long distance athletes and eight control subjects. The differences in training profiles of each group were also examined. There was no significant difference in height between the subjects, but the swimmers were younger than both the runners and controls, and both the swimmers and controls were heavier than the runners. Of all the training variables, only the mean total distance in kilometers covered per week was significantly greater in the runners. Whether based on: (a) adolescent predicted values; or (b) adult male predicted values, swimmers had significantly increased total lung capacity ((a) 145 +/- 22%, (mean +/- SD) (b) 128 +/- 15%); vital capacity ((a) 146 +/- 24%, (b) 124 +/- 15%); and inspiratory capacity ((a) 155 +/- 33%, (b) 138 +/- 29%), but this was not found in the other two groups. Swimmers also had the largest chest surface area and chest width. Forced expiratory volume in one second (FEV1) was largest in the swimmers ((b) 122 +/- 17%) and FEV1 as a percentage of forced vital capacity (FEV1/FVC)% was similar for the three groups. Pulmonary diffusing capacity (DLCO) was also highest in the swimmers (117 +/- 18%). All of the other indices of lung function, including pulmonary distensibility (K), elastic recoil and diffusion coefficient (KCO), were similar. These findings suggest that swimmers may have achieved greater lung volumes than either runners or control subjects, not because of greater inspiratory muscle strength, or differences in height, fat free mass, alveolar distensibility, age at start of training or sternal length or

  15. Ad hoc statistical consulting within a large research organization

    CSIR Research Space (South Africa)

    Elphinstone, CD

    2009-08-01

    Full Text Available requests were growing to the extent where it was difficult to manage them together with project and research workload. Also, the access to computing and some basic statistical literacy meant that a high proportion of advanced queries were received.... The challenge was to achieve this in a cost effective way with limited financial and personnel resources. Experience Some of the challenges experienced with the HotSeat service: • Researchers consulting with a statistician after the data is collected...

  16. A NICE approach to managing large numbers of desktop PC's

    International Nuclear Information System (INIS)

    Foster, David

    1996-01-01

    The problems of managing desktop systems are far from resolved. As we deploy increasing numbers of systems, PC's Mackintoshes and UN*X Workstations. This paper will concentrate on the solution adopted at CERN for the management of the rapidly increasing numbers of desktop PC's in use in all parts of the laboratory. (author)

  17. The Ramsey numbers of large cycles versus small wheels

    NARCIS (Netherlands)

    Surahmat,; Baskoro, E.T.; Broersma, H.J.

    2004-01-01

    For two given graphs G and H, the Ramsey number R(G;H) is the smallest positive integer N such that for every graph F of order N the following holds: either F contains G as a subgraph or the complement of F contains H as a subgraph. In this paper, we determine the Ramsey number R(Cn;Wm) for m = 4

  18. A new method to determine the number of experimental data using statistical modeling methods

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Jung-Ho; Kang, Young-Jin; Lim, O-Kaung; Noh, Yoojeong [Pusan National University, Busan (Korea, Republic of)

    2017-06-15

    For analyzing the statistical performance of physical systems, statistical characteristics of physical parameters such as material properties need to be estimated by collecting experimental data. For accurate statistical modeling, many such experiments may be required, but data are usually quite limited owing to the cost and time constraints of experiments. In this study, a new method for determining a rea- sonable number of experimental data is proposed using an area metric, after obtaining statistical models using the information on the underlying distribution, the Sequential statistical modeling (SSM) approach, and the Kernel density estimation (KDE) approach. The area metric is used as a convergence criterion to determine the necessary and sufficient number of experimental data to be acquired. The pro- posed method is validated in simulations, using different statistical modeling methods, different true models, and different convergence criteria. An example data set with 29 data describing the fatigue strength coefficient of SAE 950X is used for demonstrating the performance of the obtained statistical models that use a pre-determined number of experimental data in predicting the probability of failure for a target fatigue life.

  19. SWORDS: A statistical tool for analysing large DNA sequences

    Indian Academy of Sciences (India)

    Unknown

    These techniques are based on frequency distributions of DNA words in a large sequence, and have been packaged into a software called SWORDS. Using sequences available in ... tions with the cellular processes like recombination, replication .... in DNA sequences using certain specific probability laws. (Pevzner et al ...

  20. Number projected statistics and the pairing correlations at high excitation energies

    International Nuclear Information System (INIS)

    Esebbag, C.; Egido, J.L.

    1993-01-01

    We analyze the use of particle-number projected statistics (PNPS) as an effective way to include the quantum and statistical fluctuations, associated with the pairing degree of freedom, left out in finite-temperature mean-field theories. As a numerical application the exact-soluble degenerate model is worked out. In particular, we find that the sharp temperature-induced superfluid-normal phase transition, predicted in the mean-field approximations, is washed out in the PNPS. Some approximations as well as the Landau prescription to include statistical fluctuations are also discussed. We find that the Landau prescription provides a reasonable approximation to the PNPS. (orig.)

  1. Turbulent flows at very large Reynolds numbers: new lessons learned

    International Nuclear Information System (INIS)

    Barenblatt, G I; Prostokishin, V M; Chorin, A J

    2014-01-01

    The universal (Reynolds-number-independent) von Kármán–Prandtl logarithmic law for the velocity distribution in the basic intermediate region of a turbulent shear flow is generally considered to be one of the fundamental laws of engineering science and is taught universally in fluid mechanics and hydraulics courses. We show here that this law is based on an assumption that cannot be considered to be correct and which does not correspond to experiment. Nor is Landau's derivation of this law quite correct. In this paper, an alternative scaling law explicitly incorporating the influence of the Reynolds number is discussed, as is the corresponding drag law. The study uses the concept of intermediate asymptotics and that of incomplete similarity in the similarity parameter. Yakov Borisovich Zeldovich played an outstanding role in the development of these ideas. This work is a tribute to his glowing memory. (100th anniversary of the birth of ya b zeldovich)

  2. Distribution, Statistics, and Resurfacing of Large Impact Basins on Mercury

    Science.gov (United States)

    Fassett, Caleb I.; Head, James W.; Baker, David M. H.; Chapman, Clark R.; Murchie, Scott L.; Neumann, Gregory A.; Oberst, Juergen; Prockter, Louise M.; Smith, David E.; Solomon, Sean C.; hide

    2012-01-01

    The distribution and geological history of large impact basins (diameter D greater than or equal to 300 km) on Mercury is important to understanding the planet's stratigraphy and surface evolution. It is also informative to compare the density of impact basins on Mercury with that of the Moon to understand similarities and differences in their impact crater and basin populations [1, 2]. A variety of impact basins were proposed on the basis of geological mapping with Mariner 10 data [e.g. 3]. This basin population can now be re-assessed and extended to the full planet, using data from the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft. Note that small-to- medium-sized peak-ring basins on Mercury are being examined separately [4, 5]; only the three largest peak-ring basins on Mercury overlap with the size range we consider here. In this study, we (1) re-examine the large basins suggested on the basis of Mariner 10 data, (2) suggest additional basins from MESSENGER's global coverage of Mercury, (3) assess the size-frequency distribution of mercurian basins on the basis of these global observations and compare it to the Moon, and (4) analyze the implications of these observations for the modification history of basins on Mercury.

  3. Chaotic scattering: the supersymmetry method for large number of channels

    International Nuclear Information System (INIS)

    Lehmann, N.; Saher, D.; Sokolov, V.V.; Sommers, H.J.

    1995-01-01

    We investigate a model of chaotic resonance scattering based on the random matrix approach. The hermitian part of the effective hamiltonian of resonance states is taken from the GOE whereas the amplitudes of coupling to decay channels are considered both random or fixed. A new version of the supersymmetry method is worked out to determine analytically the distribution of poles of the S-matrix in the complex energy plane as well as the mean value and two-point correlation function of its elements when the number of channels scales with the number of resonance states. Analytical formulae are compared with numerical simulations. All results obtained coincide in both models provided that the ratio m of the numbers of channels and resonances is small enough and remain qualitatively similar for larger values of m. The relation between the pole distribution and the fluctuations in scattering is discussed. It is shown in particular that the clouds of poles of the S-matrix in the complex energy plane are separated from the real axis by a finite gap Γ g which determines the correlation length in the scattering fluctuations and leads to the exponential asymptotics of the decay law of a complicated intermediate state. ((orig.))

  4. Chaotic scattering: the supersymmetry method for large number of channels

    Energy Technology Data Exchange (ETDEWEB)

    Lehmann, N. (Essen Univ. (Gesamthochschule) (Germany). Fachbereich 7 - Physik); Saher, D. (Essen Univ. (Gesamthochschule) (Germany). Fachbereich 7 - Physik); Sokolov, V.V. (Essen Univ. (Gesamthochschule) (Germany). Fachbereich 7 - Physik); Sommers, H.J. (Essen Univ. (Gesamthochschule) (Germany). Fachbereich 7 - Physik)

    1995-01-23

    We investigate a model of chaotic resonance scattering based on the random matrix approach. The hermitian part of the effective hamiltonian of resonance states is taken from the GOE whereas the amplitudes of coupling to decay channels are considered both random or fixed. A new version of the supersymmetry method is worked out to determine analytically the distribution of poles of the S-matrix in the complex energy plane as well as the mean value and two-point correlation function of its elements when the number of channels scales with the number of resonance states. Analytical formulae are compared with numerical simulations. All results obtained coincide in both models provided that the ratio m of the numbers of channels and resonances is small enough and remain qualitatively similar for larger values of m. The relation between the pole distribution and the fluctuations in scattering is discussed. It is shown in particular that the clouds of poles of the S-matrix in the complex energy plane are separated from the real axis by a finite gap [Gamma][sub g] which determines the correlation length in the scattering fluctuations and leads to the exponential asymptotics of the decay law of a complicated intermediate state. ((orig.))

  5. It's a Girl! Random Numbers, Simulations, and the Law of Large Numbers

    Science.gov (United States)

    Goodwin, Chris; Ortiz, Enrique

    2015-01-01

    Modeling using mathematics and making inferences about mathematical situations are becoming more prevalent in most fields of study. Descriptive statistics cannot be used to generalize about a population or make predictions of what can occur. Instead, inference must be used. Simulation and sampling are essential in building a foundation for…

  6. TEGS-CN: A Statistical Method for Pathway Analysis of Genome-wide Copy Number Profile.

    Science.gov (United States)

    Huang, Yen-Tsung; Hsu, Thomas; Christiani, David C

    2014-01-01

    The effects of copy number alterations make up a significant part of the tumor genome profile, but pathway analyses of these alterations are still not well established. We proposed a novel method to analyze multiple copy numbers of genes within a pathway, termed Test for the Effect of a Gene Set with Copy Number data (TEGS-CN). TEGS-CN was adapted from TEGS, a method that we previously developed for gene expression data using a variance component score test. With additional development, we extend the method to analyze DNA copy number data, accounting for different sizes and thus various numbers of copy number probes in genes. The test statistic follows a mixture of X (2) distributions that can be obtained using permutation with scaled X (2) approximation. We conducted simulation studies to evaluate the size and the power of TEGS-CN and to compare its performance with TEGS. We analyzed a genome-wide copy number data from 264 patients of non-small-cell lung cancer. With the Molecular Signatures Database (MSigDB) pathway database, the genome-wide copy number data can be classified into 1814 biological pathways or gene sets. We investigated associations of the copy number profile of the 1814 gene sets with pack-years of cigarette smoking. Our analysis revealed five pathways with significant P values after Bonferroni adjustment (number data, and causal mechanisms of the five pathways require further study.

  7. Statistical properties of online avatar numbers in a massive multiplayer online role-playing game

    Science.gov (United States)

    Jiang, Zhi-Qiang; Ren, Fei; Gu, Gao-Feng; Tan, Qun-Zhao; Zhou, Wei-Xing

    2010-02-01

    Massive multiplayer online role-playing games (MMORPGs) have been very popular in the past few years. The profit of an MMORPG company is proportional to how many users registered, and the instant number of online avatars is a key factor to assess how popular an MMORPG is. We use the online-offline logs on an MMORPG server to reconstruct the instant number of online avatars per second and investigate its statistical properties. We find that the online avatar number exhibits one-day periodic behavior and clear intraday pattern, the fluctuation distribution of the online avatar numbers has a leptokurtic non-Gaussian shape with power-law tails, and the increments of online avatar numbers after removing the intraday pattern are uncorrelated and the associated absolute values have long-term correlation. In addition, both time series exhibit multifractal nature.

  8. Law of Large Numbers: the Theory, Applications and Technology-based Education.

    Science.gov (United States)

    Dinov, Ivo D; Christou, Nicolas; Gould, Robert

    2009-03-01

    Modern approaches for technology-based blended education utilize a variety of recently developed novel pedagogical, computational and network resources. Such attempts employ technology to deliver integrated, dynamically-linked, interactive-content and heterogeneous learning environments, which may improve student comprehension and information retention. In this paper, we describe one such innovative effort of using technological tools to expose students in probability and statistics courses to the theory, practice and usability of the Law of Large Numbers (LLN). We base our approach on integrating pedagogical instruments with the computational libraries developed by the Statistics Online Computational Resource (www.SOCR.ucla.edu). To achieve this merger we designed a new interactive Java applet and a corresponding demonstration activity that illustrate the concept and the applications of the LLN. The LLN applet and activity have common goals - to provide graphical representation of the LLN principle, build lasting student intuition and present the common misconceptions about the law of large numbers. Both the SOCR LLN applet and activity are freely available online to the community to test, validate and extend (Applet: http://socr.ucla.edu/htmls/exp/Coin_Toss_LLN_Experiment.html, and Activity: http://wiki.stat.ucla.edu/socr/index.php/SOCR_EduMaterials_Activities_LLN).

  9. The numbers game in wildlife conservation: changeability and framing of large mammal numbers in Zimbabwe

    NARCIS (Netherlands)

    Gandiwa, E.

    2013-01-01

    Wildlife conservation in terrestrial ecosystems requires an understanding of processes influencing population sizes. Top-down and bottom-up processes are important in large herbivore population dynamics, with strength of these processes varying spatially and temporally. However, up until

  10. On the coupling of statistic sum of canonical and large canonical ensemble of interacting particles

    International Nuclear Information System (INIS)

    Vall, A.N.

    2000-01-01

    Potentiality of refining the known result based on analytic properties of a great statistical sum, as a function of the absolute activity of the boundary integral contribution into statistical sum, is considered. A strict asymptotic ratio between statistical sums of canonical and large canonical ensemble of interacting particles was derived [ru

  11. Statistical Modeling of Large Wind Plant System's Generation - A Case Study

    International Nuclear Information System (INIS)

    Sabolic, D.

    2014-01-01

    This paper presents simplistic, yet very accurate, descriptive statistical models of various static and dynamic parameters of energy output from a large system of wind plants operated by Bonneville Power Administration (BPA), USA. The system's size at the end of 2013 was 4515 MW of installed capacity. The 5-minute readings from the beginning of 2007 to the end of 2013, recorded and published by BPA, were used to derive a number of experimental distributions, which were then used to devise theoretic statistical models with merely one or two parameters. In spite of the simplicity, they reproduced experimental data with great accuracy, which was checked by rigorous tests of goodness-of-fit. Statistical distribution functions were obtained for the following wind generation-related quantities: total generation as percentage of total installed capacity; change in total generation power in 5, 10, 15, 20, 25, 30, 45, and 60 minutes as percentage of total installed capacity; duration of intervals with total generated power, expressed as percentage of total installed capacity, lower than certain pre-specified level. Limitation of total installed wind plant capacity, when it is determined by regulation demand from wind plants, is discussed, too. The models presented here can be utilized in analyses related to power system economics/policy, which is also briefly discussed in the paper. (author).

  12. The challenge for genetic epidemiologists: how to analyze large numbers of SNPs in relation to complex diseases

    NARCIS (Netherlands)

    Heidema, A.G.; Boer, J.M.A.; Nagelkerke, N.; Mariman, E.C.M.; A, van der D.L.; Feskens, E.J.M.

    2006-01-01

    Genetic epidemiologists have taken the challenge to identify genetic polymorphisms involved in the development of diseases. Many have collected data on large numbers of genetic markers but are not familiar with available methods to assess their association with complex diseases. Statistical methods

  13. Statistical characterization of a large geochemical database and effect of sample size

    Science.gov (United States)

    Zhang, C.; Manheim, F.T.; Hinde, J.; Grossman, J.N.

    2005-01-01

    smaller numbers of data points showed that few elements passed standard statistical tests for normality or log-normality until sample size decreased to a few hundred data points. Large sample size enhances the power of statistical tests, and leads to rejection of most statistical hypotheses for real data sets. For large sample sizes (e.g., n > 1000), graphical methods such as histogram, stem-and-leaf, and probability plots are recommended for rough judgement of probability distribution if needed. ?? 2005 Elsevier Ltd. All rights reserved.

  14. Single-cell mRNA transfection studies: delivery, kinetics and statistics by numbers.

    Science.gov (United States)

    Leonhardt, Carolin; Schwake, Gerlinde; Stögbauer, Tobias R; Rappl, Susanne; Kuhr, Jan-Timm; Ligon, Thomas S; Rädler, Joachim O

    2014-05-01

    In artificial gene delivery, messenger RNA (mRNA) is an attractive alternative to plasmid DNA (pDNA) since it does not require transfer into the cell nucleus. Here we show that, unlike for pDNA transfection, the delivery statistics and dynamics of mRNA-mediated expression are generic and predictable in terms of mathematical modeling. We measured the single-cell expression time-courses and levels of enhanced green fluorescent protein (eGFP) using time-lapse microscopy and flow cytometry (FC). The single-cell analysis provides direct access to the distribution of onset times, life times and expression rates of mRNA and eGFP. We introduce a two-step stochastic delivery model that reproduces the number distribution of successfully delivered and translated mRNA molecules and thereby the dose-response relation. Our results establish a statistical framework for mRNA transfection and as such should advance the development of RNA carriers and small interfering/micro RNA-based drugs. This team of authors established a statistical framework for mRNA transfection by using a two-step stochastic delivery model that reproduces the number distribution of successfully delivered and translated mRNA molecules and thereby their dose-response relation. This study establishes a nice connection between theory and experimental planning and will aid the cellular delivery of mRNA molecules. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  15. The Application Law of Large Numbers That Predicts The Amount of Actual Loss in Insurance of Life

    Science.gov (United States)

    Tinungki, Georgina Maria

    2018-03-01

    The law of large numbers is a statistical concept that calculates the average number of events or risks in a sample or population to predict something. The larger the population is calculated, the more accurate predictions. In the field of insurance, the Law of Large Numbers is used to predict the risk of loss or claims of some participants so that the premium can be calculated appropriately. For example there is an average that of every 100 insurance participants, there is one participant who filed an accident claim, then the premium of 100 participants should be able to provide Sum Assured to at least 1 accident claim. The larger the insurance participant is calculated, the more precise the prediction of the calendar and the calculation of the premium. Life insurance, as a tool for risk spread, can only work if a life insurance company is able to bear the same risk in large numbers. Here apply what is called the law of large number. The law of large numbers states that if the amount of exposure to losses increases, then the predicted loss will be closer to the actual loss. The use of the law of large numbers allows the number of losses to be predicted better.

  16. Large-eddy simulation in a mixing tee junction: High-order turbulent statistics analysis

    International Nuclear Information System (INIS)

    Howard, Richard J.A.; Serre, Eric

    2015-01-01

    Highlights: • Mixing and thermal fluctuations in a junction are studied using large eddy simulation. • Adiabatic and conducting steel wall boundaries are tested. • Wall thermal fluctuations are not the same between the flow and the solid. • Solid thermal fluctuations cannot be predicted from the fluid thermal fluctuations. • High-order turbulent statistics show that the turbulent transport term is important. - Abstract: This study analyses the mixing and thermal fluctuations induced in a mixing tee junction with circular cross-sections when cold water flowing in a pipe is joined by hot water from a branch pipe. This configuration is representative of industrial piping systems in which temperature fluctuations in the fluid may cause thermal fatigue damage on the walls. Implicit large-eddy simulations (LES) are performed for equal inflow rates corresponding to a bulk Reynolds number Re = 39,080. Two different thermal boundary conditions are studied for the pipe walls; an insulating adiabatic boundary and a conducting steel wall boundary. The predicted flow structures show a satisfactory agreement with the literature. The velocity and thermal fields (including high-order statistics) are not affected by the heat transfer with the steel walls. However, predicted thermal fluctuations at the boundary are not the same between the flow and the solid, showing that solid thermal fluctuations cannot be predicted by the knowledge of the fluid thermal fluctuations alone. The analysis of high-order turbulent statistics provides a better understanding of the turbulence features. In particular, the budgets of the turbulent kinetic energy and temperature variance allows a comparative analysis of dissipation, production and transport terms. It is found that the turbulent transport term is an important term that acts to balance the production. We therefore use a priori tests to evaluate three different models for the triple correlation

  17. Notes on the Implementation of Non-Parametric Statistics within the Westinghouse Realistic Large Break LOCA Evaluation Model (ASTRUM)

    International Nuclear Information System (INIS)

    Frepoli, Cesare; Oriani, Luca

    2006-01-01

    In recent years, non-parametric or order statistics methods have been widely used to assess the impact of the uncertainties within Best-Estimate LOCA evaluation models. The bounding of the uncertainties is achieved with a direct Monte Carlo sampling of the uncertainty attributes, with the minimum trial number selected to 'stabilize' the estimation of the critical output values (peak cladding temperature (PCT), local maximum oxidation (LMO), and core-wide oxidation (CWO A non-parametric order statistics uncertainty analysis was recently implemented within the Westinghouse Realistic Large Break LOCA evaluation model, also referred to as 'Automated Statistical Treatment of Uncertainty Method' (ASTRUM). The implementation or interpretation of order statistics in safety analysis is not fully consistent within the industry. This has led to an extensive public debate among regulators and researchers which can be found in the open literature. The USNRC-approved Westinghouse method follows a rigorous implementation of the order statistics theory, which leads to the execution of 124 simulations within a Large Break LOCA analysis. This is a solid approach which guarantees that a bounding value (at 95% probability) of the 95 th percentile for each of the three 10 CFR 50.46 ECCS design acceptance criteria (PCT, LMO and CWO) is obtained. The objective of this paper is to provide additional insights on the ASTRUM statistical approach, with a more in-depth analysis of pros and cons of the order statistics and of the Westinghouse approach in the implementation of this statistical methodology. (authors)

  18. Detection of beamsplitting attack in a quantum cryptographic channel based on photon number statistics monitoring

    International Nuclear Information System (INIS)

    Gaidash, A A; Egorov, V I; Gleim, A V

    2014-01-01

    Quantum cryptography in theory allows distributing secure keys between two users so that any performed eavesdropping attempt would be immediately discovered. However, in practice an eavesdropper can obtain key information from multi-photon states when attenuated laser radiation is used as a source. In order to overcome this possibility, it is generally suggested to implement special cryptographic protocols, like decoy states or SARG04. We present an alternative method based on monitoring photon number statistics after detection. This method can therefore be used with any existing protocol

  19. Optimizing Statistical Character Recognition Using Evolutionary Strategies to Recognize Aircraft Tail Numbers

    Directory of Open Access Journals (Sweden)

    Antonio Berlanga

    2004-07-01

    Full Text Available The design of statistical classification systems for optical character recognition (OCR is a cumbersome task. This paper proposes a method using evolutionary strategies (ES to evolve and upgrade the set of parameters in an OCR system. This OCR is applied to identify the tail number of aircrafts moving on the airport. The proposed approach is discussed and some results are obtained using a benchmark data set. This research demonstrates the successful application of ES to a difficult, noisy, and real-world problem.

  20. Belief In Numbers: When and why women disbelieve tailored breast cancer risk statistics

    Science.gov (United States)

    Scherer, Laura D.; Ubel, Peter A.; McClure, Jennifer; Green, Sarah M.; Alford, Sharon Hensley; Holtzman, Lisa; Exe, Nicole; Fagerlin, Angela

    2013-01-01

    Objective To examine when and why women disbelieve tailored information about their risk of developing breast cancer. Methods 690 women participated in an online program to learn about medications that can reduce the risk of breast cancer. The program presented tailored information about each woman’s personal breast cancer risk. Half of women were told how their risk numbers were calculated, whereas the rest were not. Later, they were asked whether they believed that the program was personalized, and whether they believed their risk numbers. If a woman did not believe her risk numbers, she was asked to explain why. Results Beliefs that the program was personalized were enhanced by explaining the risk calculation methods in more detail. Nonetheless, nearly 20% of women did not believe their personalized risk numbers. The most common reason for rejecting the risk estimate was a belief that it did not fully account for personal and family history. Conclusions The benefits of tailored risk statistics may be attenuated by a tendency for people to be skeptical that these risk estimates apply to them personally. Practice Implications Decision aids may provide risk information that is not accepted by patients, but addressing the patients’ personal circumstances may lead to greater acceptance. PMID:23623330

  1. Identifying Copy Number Variants under Selection in Geographically Structured Populations Based on -statistics

    Directory of Open Access Journals (Sweden)

    Hae-Hiang Song

    2012-06-01

    Full Text Available Large-scale copy number variants (CNVs in the human provide the raw material for delineating population differences, as natural selection may have affected at least some of the CNVs thus far discovered. Although the examination of relatively large numbers of specific ethnic groups has recently started in regard to inter-ethnic group differences in CNVs, identifying and understanding particular instances of natural selection have not been performed. The traditional FST measure, obtained from differences in allele frequencies between populations, has been used to identify CNVs loci subject to geographically varying selection. Here, we review advances and the application of multinomial-Dirichlet likelihood methods of inference for identifying genome regions that have been subject to natural selection with the FST estimates. The contents of presentation are not new; however, this review clarifies how the application of the methods to CNV data, which remains largely unexplored, is possible. A hierarchical Bayesian method, which is implemented via Markov Chain Monte Carlo, estimates locus-specific FST and can identify outlying CNVs loci with large values of FST. By applying this Bayesian method to the publicly available CNV data, we identified the CNV loci that show signals of natural selection, which may elucidate the genetic basis of human disease and diversity.

  2. Statistical Analysis of Large Simulated Yield Datasets for Studying Climate Effects

    Science.gov (United States)

    Makowski, David; Asseng, Senthold; Ewert, Frank; Bassu, Simona; Durand, Jean-Louis; Martre, Pierre; Adam, Myriam; Aggarwal, Pramod K.; Angulo, Carlos; Baron, Chritian; hide

    2015-01-01

    Many studies have been carried out during the last decade to study the effect of climate change on crop yields and other key crop characteristics. In these studies, one or several crop models were used to simulate crop growth and development for different climate scenarios that correspond to different projections of atmospheric CO2 concentration, temperature, and rainfall changes (Semenov et al., 1996; Tubiello and Ewert, 2002; White et al., 2011). The Agricultural Model Intercomparison and Improvement Project (AgMIP; Rosenzweig et al., 2013) builds on these studies with the goal of using an ensemble of multiple crop models in order to assess effects of climate change scenarios for several crops in contrasting environments. These studies generate large datasets, including thousands of simulated crop yield data. They include series of yield values obtained by combining several crop models with different climate scenarios that are defined by several climatic variables (temperature, CO2, rainfall, etc.). Such datasets potentially provide useful information on the possible effects of different climate change scenarios on crop yields. However, it is sometimes difficult to analyze these datasets and to summarize them in a useful way due to their structural complexity; simulated yield data can differ among contrasting climate scenarios, sites, and crop models. Another issue is that it is not straightforward to extrapolate the results obtained for the scenarios to alternative climate change scenarios not initially included in the simulation protocols. Additional dynamic crop model simulations for new climate change scenarios are an option but this approach is costly, especially when a large number of crop models are used to generate the simulated data, as in AgMIP. Statistical models have been used to analyze responses of measured yield data to climate variables in past studies (Lobell et al., 2011), but the use of a statistical model to analyze yields simulated by complex

  3. Quantum probability, choice in large worlds, and the statistical structure of reality.

    Science.gov (United States)

    Ross, Don; Ladyman, James

    2013-06-01

    Classical probability models of incentive response are inadequate in "large worlds," where the dimensions of relative risk and the dimensions of similarity in outcome comparisons typically differ. Quantum probability models for choice in large worlds may be motivated pragmatically - there is no third theory - or metaphysically: statistical processing in the brain adapts to the true scale-relative structure of the universe.

  4. Dissipative Effects on Inertial-Range Statistics at High Reynolds Numbers.

    Science.gov (United States)

    Sinhuber, Michael; Bewley, Gregory P; Bodenschatz, Eberhard

    2017-09-29

    Using the unique capabilities of the Variable Density Turbulence Tunnel at the Max Planck Institute for Dynamics and Self-Organization, Göttingen, we report experimental measurements in classical grid turbulence that uncover oscillations of the velocity structure functions in the inertial range. This was made possible by measuring extremely long time series of up to 10^{10} samples of the turbulent fluctuating velocity, which corresponds to O(10^{7}) integral length scales. The measurements were conducted in a well-controlled environment at a wide range of high Reynolds numbers from R_{λ}=110 up to R_{λ}=1600, using both traditional hot-wire probes as well as the nanoscale thermal anemometry probe developed at Princeton University. An implication of the observed oscillations is that dissipation influences the inertial-range statistics of turbulent flows at scales significantly larger than predicted by current models and theories.

  5. Predicting the accumulated number of plugged tubes in a steam generator using statistical methodologies

    International Nuclear Information System (INIS)

    Ferng, Y.-M.; Fan, C.N.; Pei, B.S.; Li, H.-N.

    2008-01-01

    A steam generator (SG) plays a significant role not only with respect to the primary-to-secondary heat transfer but also as a fission product barrier to prevent the release of radionuclides. Tube plugging is an efficient way to avoid releasing radionuclides when SG tubes are severely degraded. However, this remedial action may cause the decrease of SG heat transfer capability, especially in transient or accident conditions. It is therefore crucial for the plant staff to understand the trend of plugged tubes for the SG operation and maintenance. Statistical methodologies are proposed in this paper to predict this trend. The accumulated numbers of SG plugged tubes versus the operation time are predicted using the Weibull and log-normal distributions, which correspond well with the plant measured data from a selected pressurized water reactor (PWR). With the help of these predictions, the accumulated number of SG plugged tubes can be reasonably extrapolated to the 40-year operation lifetime (or even longer than 40 years) of a PWR. This information can assist the plant policymakers to determine whether or when a SG must be replaced

  6. Fractional statistics, exceptional preons, scalar dark matter, lepton number violation, neutrino masses, and hidden gauge structure

    International Nuclear Information System (INIS)

    Zee, A.

    1985-09-01

    A brief review is given of the basics of fractional statistics, which is based on the Dirac-Bohm-Aharanov effect. Some group theoretic aspects of exceptional preons are breifly described, and a theory is proposed containing hypercolor and hyperflavor with G/sub HC/ x G/sub HF/ = E(6) x E(6) and preons in (27,27). It is also suggested that the dark matter in the universe is due to a scalar field which transforms as a singlet under SU(3) x SU(2) x U(1) and interacts only via the Higgs boson. Some speculation is made on the existence and physical consequences of a SU(2) singet charged scalar field which couples to two lepton doublet, necessarily violating electron, muon, and tauon numbers. The Majorana masses of neutrinos are discussed as the result of breaking the total lepton number. Abelian gauge field hidden inside non-abelian gauge theory is briefly described in analogy to the electromagnetic potential term. 20 refs

  7. Tracking of large-scale structures in turbulent channel with direct numerical simulation of low Prandtl number passive scalar

    Science.gov (United States)

    Tiselj, Iztok

    2014-12-01

    Channel flow DNS (Direct Numerical Simulation) at friction Reynolds number 180 and with passive scalars of Prandtl numbers 1 and 0.01 was performed in various computational domains. The "normal" size domain was ˜2300 wall units long and ˜750 wall units wide; size taken from the similar DNS of Moser et al. The "large" computational domain, which is supposed to be sufficient to describe the largest structures of the turbulent flows was 3 times longer and 3 times wider than the "normal" domain. The "very large" domain was 6 times longer and 6 times wider than the "normal" domain. All simulations were performed with the same spatial and temporal resolution. Comparison of the standard and large computational domains shows the velocity field statistics (mean velocity, root-mean-square (RMS) fluctuations, and turbulent Reynolds stresses) that are within 1%-2%. Similar agreement is observed for Pr = 1 temperature fields and can be observed also for the mean temperature profiles at Pr = 0.01. These differences can be attributed to the statistical uncertainties of the DNS. However, second-order moments, i.e., RMS temperature fluctuations of standard and large computational domains at Pr = 0.01 show significant differences of up to 20%. Stronger temperature fluctuations in the "large" and "very large" domains confirm the existence of the large-scale structures. Their influence is more or less invisible in the main velocity field statistics or in the statistics of the temperature fields at Prandtl numbers around 1. However, these structures play visible role in the temperature fluctuations at low Prandtl number, where high temperature diffusivity effectively smears the small-scale structures in the thermal field and enhances the relative contribution of large-scales. These large thermal structures represent some kind of an echo of the large scale velocity structures: the highest temperature-velocity correlations are not observed between the instantaneous temperatures and

  8. Lensing corrections to the Eg(z) statistics from large scale structure

    Science.gov (United States)

    Moradinezhad Dizgah, Azadeh; Durrer, Ruth

    2016-09-01

    We study the impact of the often neglected lensing contribution to galaxy number counts on the Eg statistics which is used to constrain deviations from GR. This contribution affects both the galaxy-galaxy and the convergence-galaxy spectra, while it is larger for the latter. At higher redshifts probed by upcoming surveys, for instance at z = 1.5, neglecting this term induces an error of (25-40)% in the spectra and therefore on the Eg statistics which is constructed from the combination of the two. Moreover, including it, renders the Eg statistics scale and bias-dependent and hence puts into question its very objective.

  9. Comparison of Statistical Algorithms for the Detection of Infectious Disease Outbreaks in Large Multiple Surveillance Systems

    Science.gov (United States)

    Farrington, C. Paddy; Noufaily, Angela; Andrews, Nick J.; Charlett, Andre

    2016-01-01

    A large-scale multiple surveillance system for infectious disease outbreaks has been in operation in England and Wales since the early 1990s. Changes to the statistical algorithm at the heart of the system were proposed and the purpose of this paper is to compare two new algorithms with the original algorithm. Test data to evaluate performance are created from weekly counts of the number of cases of each of more than 2000 diseases over a twenty-year period. The time series of each disease is separated into one series giving the baseline (background) disease incidence and a second series giving disease outbreaks. One series is shifted forward by twelve months and the two are then recombined, giving a realistic series in which it is known where outbreaks have been added. The metrics used to evaluate performance include a scoring rule that appropriately balances sensitivity against specificity and is sensitive to variation in probabilities near 1. In the context of disease surveillance, a scoring rule can be adapted to reflect the size of outbreaks and this was done. Results indicate that the two new algorithms are comparable to each other and better than the algorithm they were designed to replace. PMID:27513749

  10. Number of deaths due to lung diseases: How large is the problem?

    International Nuclear Information System (INIS)

    Wagener, D.K.

    1990-01-01

    The importance of lung disease as an indicator of environmentally induced adverse health effects has been recognized by inclusion among the Health Objectives for the Nation. The 1990 Health Objectives for the Nation (US Department of Health and Human Services, 1986) includes an objective that there should be virtually no new cases among newly exposed workers for four preventable occupational lung diseases-asbestosis, byssinosis, silicosis, and coal workers' pneumoconiosis. This brief communication describes two types of cause-of-death statistics- underlying and multiple cause-and demonstrates the differences between the two statistics using lung disease deaths among adult men. The choice of statistic has a large impact on estimated lung disease mortality rates. The choice of statistics also may have large effect on the estimated mortality rates due to other chromic diseases thought to be environmentally mediated. Issues of comorbidity and the way causes of death are reported become important in the interpretation of these statistics. The choice of which statistic to use when comparing data from a study population with national statistics may greatly affect the interpretations of the study findings

  11. On metal-oxygen coordination. A statistical method to determine coordination number. Pt. 1

    International Nuclear Information System (INIS)

    Chiari, G.

    1990-01-01

    The environment around the Ca cation for compounds involving bonded oxygen has been studied for 254 inorganic structures containing a total of 368 polyhedra. Selection was made on the bases of the accuracy of the structural data. The coordination number (CN) was assigned using the criteria of maximum gap in the Ca-O distances and balanced bond-valence sums for Ca, but 32 cases were still difficult to assign unambiguously. A series of variables related to the Ca-O distances were calculated and averaged for each value of CN. The Gaussian curves representing the distribution of these variables for each CN overlap strongly. By way of contrast, the volume of the coordination polyhedra (Vol) showed well separated curves. Statistical analysis was applied to the set of structures with known CN, with seven variables and then with Vol alone, which seems to discriminate between the various CN groups equally well. A strong linear dependence was found for CN versus Vol. A method is proposed to assign CN in uncertain cases based on the equation: CN=0.197 (2)Vol+2.83 (5). Application of this equation to the unassigned cases compares favourably with discriminant analysis using the larger set of variables. (orig.)

  12. Dark matter statistics for large galaxy catalogs: power spectra and covariance matrices

    Science.gov (United States)

    Klypin, Anatoly; Prada, Francisco

    2018-06-01

    Large-scale surveys of galaxies require accurate theoretical predictions of the dark matter clustering for thousands of mock galaxy catalogs. We demonstrate that this goal can be achieve with the new Parallel Particle-Mesh (PM) N-body code GLAM at a very low computational cost. We run ˜22, 000 simulations with ˜2 billion particles that provide ˜1% accuracy of the dark matter power spectra P(k) for wave-numbers up to k ˜ 1hMpc-1. Using this large data-set we study the power spectrum covariance matrix. In contrast to many previous analytical and numerical results, we find that the covariance matrix normalised to the power spectrum C(k, k΄)/P(k)P(k΄) has a complex structure of non-diagonal components: an upturn at small k, followed by a minimum at k ≈ 0.1 - 0.2 hMpc-1, and a maximum at k ≈ 0.5 - 0.6 hMpc-1. The normalised covariance matrix strongly evolves with redshift: C(k, k΄)∝δα(t)P(k)P(k΄), where δ is the linear growth factor and α ≈ 1 - 1.25, which indicates that the covariance matrix depends on cosmological parameters. We also show that waves longer than 1h-1Gpc have very little impact on the power spectrum and covariance matrix. This significantly reduces the computational costs and complexity of theoretical predictions: relatively small volume ˜(1h-1Gpc)3 simulations capture the necessary properties of dark matter clustering statistics. As our results also indicate, achieving ˜1% errors in the covariance matrix for k < 0.50 hMpc-1 requires a resolution better than ɛ ˜ 0.5h-1Mpc.

  13. Large-Deviation Results for Discriminant Statistics of Gaussian Locally Stationary Processes

    Directory of Open Access Journals (Sweden)

    Junichi Hirukawa

    2012-01-01

    Full Text Available This paper discusses the large-deviation principle of discriminant statistics for Gaussian locally stationary processes. First, large-deviation theorems for quadratic forms and the log-likelihood ratio for a Gaussian locally stationary process with a mean function are proved. Their asymptotics are described by the large deviation rate functions. Second, we consider the situations where processes are misspecified to be stationary. In these misspecified cases, we formally make the log-likelihood ratio discriminant statistics and derive the large deviation theorems of them. Since they are complicated, they are evaluated and illustrated by numerical examples. We realize the misspecification of the process to be stationary seriously affecting our discrimination.

  14. Multivariate statistical analysis software technologies for astrophysical research involving large data bases

    Science.gov (United States)

    Djorgovski, S. George

    1994-01-01

    We developed a package to process and analyze the data from the digital version of the Second Palomar Sky Survey. This system, called SKICAT, incorporates the latest in machine learning and expert systems software technology, in order to classify the detected objects objectively and uniformly, and facilitate handling of the enormous data sets from digital sky surveys and other sources. The system provides a powerful, integrated environment for the manipulation and scientific investigation of catalogs from virtually any source. It serves three principal functions: image catalog construction, catalog management, and catalog analysis. Through use of the GID3* Decision Tree artificial induction software, SKICAT automates the process of classifying objects within CCD and digitized plate images. To exploit these catalogs, the system also provides tools to merge them into a large, complete database which may be easily queried and modified when new data or better methods of calibrating or classifying become available. The most innovative feature of SKICAT is the facility it provides to experiment with and apply the latest in machine learning technology to the tasks of catalog construction and analysis. SKICAT provides a unique environment for implementing these tools for any number of future scientific purposes. Initial scientific verification and performance tests have been made using galaxy counts and measurements of galaxy clustering from small subsets of the survey data, and a search for very high redshift quasars. All of the tests were successful, and produced new and interesting scientific results. Attachments to this report give detailed accounts of the technical aspects for multivariate statistical analysis of small and moderate-size data sets, called STATPROG. The package was tested extensively on a number of real scientific applications, and has produced real, published results.

  15. Multivariate Statistical Analysis Software Technologies for Astrophysical Research Involving Large Data Bases

    Science.gov (United States)

    Djorgovski, S. G.

    1994-01-01

    We developed a package to process and analyze the data from the digital version of the Second Palomar Sky Survey. This system, called SKICAT, incorporates the latest in machine learning and expert systems software technology, in order to classify the detected objects objectively and uniformly, and facilitate handling of the enormous data sets from digital sky surveys and other sources. The system provides a powerful, integrated environment for the manipulation and scientific investigation of catalogs from virtually any source. It serves three principal functions: image catalog construction, catalog management, and catalog analysis. Through use of the GID3* Decision Tree artificial induction software, SKICAT automates the process of classifying objects within CCD and digitized plate images. To exploit these catalogs, the system also provides tools to merge them into a large, complex database which may be easily queried and modified when new data or better methods of calibrating or classifying become available. The most innovative feature of SKICAT is the facility it provides to experiment with and apply the latest in machine learning technology to the tasks of catalog construction and analysis. SKICAT provides a unique environment for implementing these tools for any number of future scientific purposes. Initial scientific verification and performance tests have been made using galaxy counts and measurements of galaxy clustering from small subsets of the survey data, and a search for very high redshift quasars. All of the tests were successful and produced new and interesting scientific results. Attachments to this report give detailed accounts of the technical aspects of the SKICAT system, and of some of the scientific results achieved to date. We also developed a user-friendly package for multivariate statistical analysis of small and moderate-size data sets, called STATPROG. The package was tested extensively on a number of real scientific applications and has

  16. Statistical analysis of fuel failures in large break loss-of-coolant accident (LBLOCA) in EPR type nuclear power plant

    International Nuclear Information System (INIS)

    Arkoma, Asko; Hänninen, Markku; Rantamäki, Karin; Kurki, Joona; Hämäläinen, Anitta

    2015-01-01

    Highlights: • The number of failing fuel rods in a LB-LOCA in an EPR is evaluated. • 59 scenarios are simulated with the system code APROS. • 1000 rods per scenario are simulated with the fuel performance code FRAPTRAN-GENFLO. • All the rods in the reactor are simulated in the worst scenario. • Results suggest that the regulations set by the Finnish safety authority are met. - Abstract: In this paper, the number of failing fuel rods in a large break loss-of-coolant accident (LB-LOCA) in EPR-type nuclear power plant is evaluated using statistical methods. For this purpose, a statistical fuel failure analysis procedure has been developed. The developed method utilizes the results of nonparametric statistics, the Wilks’ formula in particular, and is based on the selection and variation of parameters that are important in accident conditions. The accident scenario is simulated with the coupled fuel performance – thermal hydraulics code FRAPTRAN-GENFLO using various parameter values and thermal hydraulic and power history boundary conditions between the simulations. The number of global scenarios is 59 (given by the Wilks’ formula), and 1000 rods are simulated in each scenario. The boundary conditions are obtained from a new statistical version of the system code APROS. As a result, in the worst global scenario, 1.2% of the simulated rods failed, and it can be concluded that the Finnish safety regulations are hereby met (max. 10% of the rods allowed to fail)

  17. Statistical analysis of fuel failures in large break loss-of-coolant accident (LBLOCA) in EPR type nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Arkoma, Asko, E-mail: asko.arkoma@vtt.fi; Hänninen, Markku; Rantamäki, Karin; Kurki, Joona; Hämäläinen, Anitta

    2015-04-15

    Highlights: • The number of failing fuel rods in a LB-LOCA in an EPR is evaluated. • 59 scenarios are simulated with the system code APROS. • 1000 rods per scenario are simulated with the fuel performance code FRAPTRAN-GENFLO. • All the rods in the reactor are simulated in the worst scenario. • Results suggest that the regulations set by the Finnish safety authority are met. - Abstract: In this paper, the number of failing fuel rods in a large break loss-of-coolant accident (LB-LOCA) in EPR-type nuclear power plant is evaluated using statistical methods. For this purpose, a statistical fuel failure analysis procedure has been developed. The developed method utilizes the results of nonparametric statistics, the Wilks’ formula in particular, and is based on the selection and variation of parameters that are important in accident conditions. The accident scenario is simulated with the coupled fuel performance – thermal hydraulics code FRAPTRAN-GENFLO using various parameter values and thermal hydraulic and power history boundary conditions between the simulations. The number of global scenarios is 59 (given by the Wilks’ formula), and 1000 rods are simulated in each scenario. The boundary conditions are obtained from a new statistical version of the system code APROS. As a result, in the worst global scenario, 1.2% of the simulated rods failed, and it can be concluded that the Finnish safety regulations are hereby met (max. 10% of the rods allowed to fail)

  18. Statistical physics as an approximate method of many-body quantum mechanics in the representation of occupation numbers

    International Nuclear Information System (INIS)

    Kushnirenko, A.N.

    1989-01-01

    An attempt was made to substantiate statistical physics from the viewpoint of many-body quantum mechanics in the representation of occupation numbers. This approach enabled to develop the variation method for solution of stationary and nonstationary nonequilibrium problems

  19. Statistics

    CERN Document Server

    Hayslett, H T

    1991-01-01

    Statistics covers the basic principles of Statistics. The book starts by tackling the importance and the two kinds of statistics; the presentation of sample data; the definition, illustration and explanation of several measures of location; and the measures of variation. The text then discusses elementary probability, the normal distribution and the normal approximation to the binomial. Testing of statistical hypotheses and tests of hypotheses about the theoretical proportion of successes in a binomial population and about the theoretical mean of a normal population are explained. The text the

  20. Correlation between the number of quantum-statistical modes of the exciting field and the number of lines in the resonance fluorescence spectrum

    International Nuclear Information System (INIS)

    Kryzhanovskii, Boris V; Sokolov, G B

    2000-01-01

    The quasi-energy wave functions of a two-level atom in an electromagnetic field, the state of which represents a superposition of coherent states, were found. The fluorescence spectrum of an atom excited by such a field was investigated. It was shown that a spectral fluorescence mode corresponds to each mode of the quantum-statistical distribution of the field incident on the atom. This means that the number of statistical modes of the incident field may be recorded as the number of data bits of the information carried by the light pulse. (laser applications and other topics in quantum electronics)

  1. Current fluctuations and statistics during a large deviation event in an exactly solvable transport model

    International Nuclear Information System (INIS)

    Hurtado, Pablo I; Garrido, Pedro L

    2009-01-01

    We study the distribution of the time-integrated current in an exactly solvable toy model of heat conduction, both analytically and numerically. The simplicity of the model allows us to derive the full current large deviation function and the system statistics during a large deviation event. In this way we unveil a relation between system statistics at the end of a large deviation event and for intermediate times. The mid-time statistics is independent of the sign of the current, a reflection of the time-reversal symmetry of microscopic dynamics, while the end-time statistics does depend on the current sign, and also on its microscopic definition. We compare our exact results with simulations based on the direct evaluation of large deviation functions, analyzing the finite-size corrections of this simulation method and deriving detailed bounds for its applicability. We also show how the Gallavotti–Cohen fluctuation theorem can be used to determine the range of validity of simulation results

  2. The Impact of a Flipped Classroom Model of Learning on a Large Undergraduate Statistics Class

    Science.gov (United States)

    Nielson, Perpetua Lynne; Bean, Nathan William Bean; Larsen, Ross Allen Andrew

    2018-01-01

    We examine the impact of a flipped classroom model of learning on student performance and satisfaction in a large undergraduate introductory statistics class. Two professors each taught a lecture-section and a flipped-class section. Using MANCOVA, a linear combination of final exam scores, average quiz scores, and course ratings was compared for…

  3. Error Analysis of Statistical Linearization with Gaussian Closure for Large Degree-of-Freedom Systems

    DEFF Research Database (Denmark)

    Micaletti, R. C.; Cakmak, A. S.; Nielsen, Søren R. K.

    This paper contains an analyses of the error induced by applying the method of the equivalent statistical linearzation (ESL) to randomly-exited multi-degree-of-freedom (MDOF) geometrically nonlinear shear-frame structures as the number of degrees of freedom increases. The quantity that is analyzed...

  4. Statistics and Dynamics in the Large-scale Structure of the Universe

    International Nuclear Information System (INIS)

    Matsubara, Takahiko

    2006-01-01

    In cosmology, observations and theories are related to each other by statistics in most cases. Especially, statistical methods play central roles in analyzing fluctuations in the universe, which are seeds of the present structure of the universe. The confrontation of the statistics and dynamics is one of the key methods to unveil the structure and evolution of the universe. I will review some of the major statistical methods in cosmology, in connection with linear and nonlinear dynamics of the large-scale structure of the universe. The present status of analyses of the observational data such as the Sloan Digital Sky Survey, and the future prospects to constrain the nature of exotic components of the universe such as the dark energy will be presented

  5. Characterization of General TCP Traffic under a Large Number of Flows Regime

    National Research Council Canada - National Science Library

    Tinnakornsrisuphap, Peerapol; La, Richard J; Makowski, Armand M

    2002-01-01

    .... Accurate traffic modeling of a large number of short-lived TCP flows is extremely difficult due to the interaction between session, transport, and network layers, and the explosion of the size...

  6. Radioimmunoassay of h-TSH - methodological suggestions for dealing with medium to large numbers of samples

    International Nuclear Information System (INIS)

    Mahlstedt, J.

    1977-01-01

    The article deals with practical aspects of establishing a TSH-RIA for patients, with particular regard to predetermined quality criteria. Methodological suggestions are made for medium to large numbers of samples with the target of reducing monotonous precision working steps by means of simple aids. The quality criteria required are well met, while the test procedure is well adapted to the rhythm of work and may be carried out without loss of precision even with large numbers of samples. (orig.) [de

  7. Similarities between 2D and 3D convection for large Prandtl number

    Indian Academy of Sciences (India)

    2016-06-18

    RBC), we perform a compara- tive study of the spectra and fluxes of energy and entropy, and the scaling of large-scale quantities for large and infinite Prandtl numbers in two (2D) and three (3D) dimensions. We observe close ...

  8. Very Large Data Volumes Analysis of Collaborative Systems with Finite Number of States

    Science.gov (United States)

    Ivan, Ion; Ciurea, Cristian; Pavel, Sorin

    2010-01-01

    The collaborative system with finite number of states is defined. A very large database is structured. Operations on large databases are identified. Repetitive procedures for collaborative systems operations are derived. The efficiency of such procedures is analyzed. (Contains 6 tables, 5 footnotes and 3 figures.)

  9. Evidence for Knowledge of the Syntax of Large Numbers in Preschoolers

    Science.gov (United States)

    Barrouillet, Pierre; Thevenot, Catherine; Fayol, Michel

    2010-01-01

    The aim of this study was to provide evidence for knowledge of the syntax governing the verbal form of large numbers in preschoolers long before they are able to count up to these numbers. We reasoned that if such knowledge exists, it should facilitate the maintenance in short-term memory of lists of lexical primitives that constitute a number…

  10. Uses and misuses of statistics: the case of strontium ranelate and the number needed to treat.

    Science.gov (United States)

    Pedrazzoni, M; Giusti, A; Pioli, G

    2011-09-01

    In the last 15 years, several pharmacological agents for the prevention of fractures have been developed and commercialized. Most of them showed to be effective in reducing fracture risk. The enhanced availability of drugs to prevent fractures has generated a fierce competition among pharmaceutical companies to conquer a share of the potential market, often with claims of superiority of a drug over another without direct comparisons. The definitive way to compare different treatments would require randomized head to head trials. These trials are expensive, need large samples and are unlikely to be ever performed. Therefore, it has become a common practice to compare pharmacological agents through observational studies on administrative databases or by the indirect comparison of the results of individual randomised-controlled trials (RCT) and their meta-analyses. These studies may produce evidence of clinical value, complementary to that given by RCT. However, without a proper and complete analysis, they may result in a biased picture of effectiveness and be completely misleading. In this article, we critically disclose how such competition may produce biased and misleading picture of evidence, by reviewing the significance of the number needed to treat, absolute risk reduction and relative risk reduction in relation to vertebral fractures prevention with available drugs.

  11. Statistics

    Science.gov (United States)

    Links to sources of cancer-related statistics, including the Surveillance, Epidemiology and End Results (SEER) Program, SEER-Medicare datasets, cancer survivor prevalence data, and the Cancer Trends Progress Report.

  12. Reliability and statistical power analysis of cortical and subcortical FreeSurfer metrics in a large sample of healthy elderly.

    Science.gov (United States)

    Liem, Franziskus; Mérillat, Susan; Bezzola, Ladina; Hirsiger, Sarah; Philipp, Michel; Madhyastha, Tara; Jäncke, Lutz

    2015-03-01

    FreeSurfer is a tool to quantify cortical and subcortical brain anatomy automatically and noninvasively. Previous studies have reported reliability and statistical power analyses in relatively small samples or only selected one aspect of brain anatomy. Here, we investigated reliability and statistical power of cortical thickness, surface area, volume, and the volume of subcortical structures in a large sample (N=189) of healthy elderly subjects (64+ years). Reliability (intraclass correlation coefficient) of cortical and subcortical parameters is generally high (cortical: ICCs>0.87, subcortical: ICCs>0.95). Surface-based smoothing increases reliability of cortical thickness maps, while it decreases reliability of cortical surface area and volume. Nevertheless, statistical power of all measures benefits from smoothing. When aiming to detect a 10% difference between groups, the number of subjects required to test effects with sufficient power over the entire cortex varies between cortical measures (cortical thickness: N=39, surface area: N=21, volume: N=81; 10mm smoothing, power=0.8, α=0.05). For subcortical regions this number is between 16 and 76 subjects, depending on the region. We also demonstrate the advantage of within-subject designs over between-subject designs. Furthermore, we publicly provide a tool that allows researchers to perform a priori power analysis and sensitivity analysis to help evaluate previously published studies and to design future studies with sufficient statistical power. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Eulerian short-time statistics of turbulent flow at large Reynolds number

    NARCIS (Netherlands)

    Brouwers, J.J.H.

    2004-01-01

    An asymptotic analysis is presented of the short-time behavior of second-order temporal velocity structure functions and Eulerian acceleration correlations in a frame that moves with the local mean velocity of the turbulent flow field. Expressions in closed-form are derived which cover the viscous

  14. Testing the statistical isotropy of large scale structure with multipole vectors

    International Nuclear Information System (INIS)

    Zunckel, Caroline; Huterer, Dragan; Starkman, Glenn D.

    2011-01-01

    A fundamental assumption in cosmology is that of statistical isotropy - that the Universe, on average, looks the same in every direction in the sky. Statistical isotropy has recently been tested stringently using cosmic microwave background data, leading to intriguing results on large angular scales. Here we apply some of the same techniques used in the cosmic microwave background to the distribution of galaxies on the sky. Using the multipole vector approach, where each multipole in the harmonic decomposition of galaxy density field is described by unit vectors and an amplitude, we lay out the basic formalism of how to reconstruct the multipole vectors and their statistics out of galaxy survey catalogs. We apply the algorithm to synthetic galaxy maps, and study the sensitivity of the multipole vector reconstruction accuracy to the density, depth, sky coverage, and pixelization of galaxy catalog maps.

  15. Elementary methods for statistical systems, mean field, large-n, and duality

    International Nuclear Information System (INIS)

    Itzykson, C.

    1983-01-01

    Renormalizable field theories are singled out by such precise restraints that regularization schemes must be used to break these invariances. Statistical methods can be adapted to these problems where asymptotically free models fail. This lecture surveys approximation schemes developed in the context of statistical mechanics. The confluence point of statistical mechanics and field theory is the use of discretized path integrals, where continuous space time has been replaced by a regular lattice. Dynamic variables, a Boltzman weight factor, and boundary conditions are the ingredients. Mean field approximations --field equations, Random field transform, and gauge invariant systems--are surveyed. Under Large-N limits vector models are found to simplify tremendously. The reasons why matrix models drawn from SU (n) gauge theories do not simplify are discussed. In the epilogue, random curves versus random surfaces are offered as an example where global and local symmetries are not alike

  16. Lensing corrections to the E {sub g} ( z ) statistics from large scale structure

    Energy Technology Data Exchange (ETDEWEB)

    Dizgah, Azadeh Moradinezhad; Durrer, Ruth, E-mail: Azadeh.Moradinezhad@unige.ch, E-mail: Ruth.Durrer@unige.ch [Department of Theoretical Physics and Center for Astroparticle Physics, University of Geneva, 24 quai E. Ansermet, CH-1211 Geneva 4 (Switzerland)

    2016-09-01

    We study the impact of the often neglected lensing contribution to galaxy number counts on the E {sub g} statistics which is used to constrain deviations from GR. This contribution affects both the galaxy-galaxy and the convergence-galaxy spectra, while it is larger for the latter. At higher redshifts probed by upcoming surveys, for instance at z = 1.5, neglecting this term induces an error of (25–40)% in the spectra and therefore on the E {sub g} statistics which is constructed from the combination of the two. Moreover, including it, renders the E {sub g} statistics scale and bias-dependent and hence puts into question its very objective.

  17. Data management in large-scale collaborative toxicity studies: how to file experimental data for automated statistical analysis.

    Science.gov (United States)

    Stanzel, Sven; Weimer, Marc; Kopp-Schneider, Annette

    2013-06-01

    High-throughput screening approaches are carried out for the toxicity assessment of a large number of chemical compounds. In such large-scale in vitro toxicity studies several hundred or thousand concentration-response experiments are conducted. The automated evaluation of concentration-response data using statistical analysis scripts saves time and yields more consistent results in comparison to data analysis performed by the use of menu-driven statistical software. Automated statistical analysis requires that concentration-response data are available in a standardised data format across all compounds. To obtain consistent data formats, a standardised data management workflow must be established, including guidelines for data storage, data handling and data extraction. In this paper two procedures for data management within large-scale toxicological projects are proposed. Both procedures are based on Microsoft Excel files as the researcher's primary data format and use a computer programme to automate the handling of data files. The first procedure assumes that data collection has not yet started whereas the second procedure can be used when data files already exist. Successful implementation of the two approaches into the European project ACuteTox is illustrated. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Statistics

    International Nuclear Information System (INIS)

    2005-01-01

    For the years 2004 and 2005 the figures shown in the tables of Energy Review are partly preliminary. The annual statistics published in Energy Review are presented in more detail in a publication called Energy Statistics that comes out yearly. Energy Statistics also includes historical time-series over a longer period of time (see e.g. Energy Statistics, Statistics Finland, Helsinki 2004.) The applied energy units and conversion coefficients are shown in the back cover of the Review. Explanatory notes to the statistical tables can be found after tables and figures. The figures presents: Changes in GDP, energy consumption and electricity consumption, Carbon dioxide emissions from fossile fuels use, Coal consumption, Consumption of natural gas, Peat consumption, Domestic oil deliveries, Import prices of oil, Consumer prices of principal oil products, Fuel prices in heat production, Fuel prices in electricity production, Price of electricity by type of consumer, Average monthly spot prices at the Nord pool power exchange, Total energy consumption by source and CO 2 -emissions, Supplies and total consumption of electricity GWh, Energy imports by country of origin in January-June 2003, Energy exports by recipient country in January-June 2003, Consumer prices of liquid fuels, Consumer prices of hard coal, natural gas and indigenous fuels, Price of natural gas by type of consumer, Price of electricity by type of consumer, Price of district heating by type of consumer, Excise taxes, value added taxes and fiscal charges and fees included in consumer prices of some energy sources and Energy taxes, precautionary stock fees and oil pollution fees

  19. Numerical and analytical approaches to an advection-diffusion problem at small Reynolds number and large Péclet number

    Science.gov (United States)

    Fuller, Nathaniel J.; Licata, Nicholas A.

    2018-05-01

    Obtaining a detailed understanding of the physical interactions between a cell and its environment often requires information about the flow of fluid surrounding the cell. Cells must be able to effectively absorb and discard material in order to survive. Strategies for nutrient acquisition and toxin disposal, which have been evolutionarily selected for their efficacy, should reflect knowledge of the physics underlying this mass transport problem. Motivated by these considerations, in this paper we discuss the results from an undergraduate research project on the advection-diffusion equation at small Reynolds number and large Péclet number. In particular, we consider the problem of mass transport for a Stokesian spherical swimmer. We approach the problem numerically and analytically through a rescaling of the concentration boundary layer. A biophysically motivated first-passage problem for the absorption of material by the swimming cell demonstrates quantitative agreement between the numerical and analytical approaches. We conclude by discussing the connections between our results and the design of smart toxin disposal systems.

  20. A comparative analysis of the statistical properties of large mobile phone calling networks.

    Science.gov (United States)

    Li, Ming-Xia; Jiang, Zhi-Qiang; Xie, Wen-Jie; Miccichè, Salvatore; Tumminello, Michele; Zhou, Wei-Xing; Mantegna, Rosario N

    2014-05-30

    Mobile phone calling is one of the most widely used communication methods in modern society. The records of calls among mobile phone users provide us a valuable proxy for the understanding of human communication patterns embedded in social networks. Mobile phone users call each other forming a directed calling network. If only reciprocal calls are considered, we obtain an undirected mutual calling network. The preferential communication behavior between two connected users can be statistically tested and it results in two Bonferroni networks with statistically validated edges. We perform a comparative analysis of the statistical properties of these four networks, which are constructed from the calling records of more than nine million individuals in Shanghai over a period of 110 days. We find that these networks share many common structural properties and also exhibit idiosyncratic features when compared with previously studied large mobile calling networks. The empirical findings provide us an intriguing picture of a representative large social network that might shed new lights on the modelling of large social networks.

  1. Statistics

    International Nuclear Information System (INIS)

    2001-01-01

    For the year 2000, part of the figures shown in the tables of the Energy Review are preliminary or estimated. The annual statistics of the Energy Review appear in more detail from the publication Energiatilastot - Energy Statistics issued annually, which also includes historical time series over a longer period (see e.g. Energiatilastot 1999, Statistics Finland, Helsinki 2000, ISSN 0785-3165). The inside of the Review's back cover shows the energy units and the conversion coefficients used for them. Explanatory notes to the statistical tables can be found after tables and figures. The figures presents: Changes in the volume of GNP and energy consumption, Changes in the volume of GNP and electricity, Coal consumption, Natural gas consumption, Peat consumption, Domestic oil deliveries, Import prices of oil, Consumer prices of principal oil products, Fuel prices for heat production, Fuel prices for electricity production, Carbon dioxide emissions from the use of fossil fuels, Total energy consumption by source and CO 2 -emissions, Electricity supply, Energy imports by country of origin in 2000, Energy exports by recipient country in 2000, Consumer prices of liquid fuels, Consumer prices of hard coal, natural gas and indigenous fuels, Average electricity price by type of consumer, Price of district heating by type of consumer, Excise taxes, value added taxes and fiscal charges and fees included in consumer prices of some energy sources and Energy taxes and precautionary stock fees on oil products

  2. Statistics

    International Nuclear Information System (INIS)

    2000-01-01

    For the year 1999 and 2000, part of the figures shown in the tables of the Energy Review are preliminary or estimated. The annual statistics of the Energy Review appear in more detail from the publication Energiatilastot - Energy Statistics issued annually, which also includes historical time series over a longer period (see e.g., Energiatilastot 1998, Statistics Finland, Helsinki 1999, ISSN 0785-3165). The inside of the Review's back cover shows the energy units and the conversion coefficients used for them. Explanatory notes to the statistical tables can be found after tables and figures. The figures presents: Changes in the volume of GNP and energy consumption, Changes in the volume of GNP and electricity, Coal consumption, Natural gas consumption, Peat consumption, Domestic oil deliveries, Import prices of oil, Consumer prices of principal oil products, Fuel prices for heat production, Fuel prices for electricity production, Carbon dioxide emissions, Total energy consumption by source and CO 2 -emissions, Electricity supply, Energy imports by country of origin in January-March 2000, Energy exports by recipient country in January-March 2000, Consumer prices of liquid fuels, Consumer prices of hard coal, natural gas and indigenous fuels, Average electricity price by type of consumer, Price of district heating by type of consumer, Excise taxes, value added taxes and fiscal charges and fees included in consumer prices of some energy sources and Energy taxes and precautionary stock fees on oil products

  3. Statistics

    International Nuclear Information System (INIS)

    1999-01-01

    For the year 1998 and the year 1999, part of the figures shown in the tables of the Energy Review are preliminary or estimated. The annual statistics of the Energy Review appear in more detail from the publication Energiatilastot - Energy Statistics issued annually, which also includes historical time series over a longer period (see e.g. Energiatilastot 1998, Statistics Finland, Helsinki 1999, ISSN 0785-3165). The inside of the Review's back cover shows the energy units and the conversion coefficients used for them. Explanatory notes to the statistical tables can be found after tables and figures. The figures presents: Changes in the volume of GNP and energy consumption, Changes in the volume of GNP and electricity, Coal consumption, Natural gas consumption, Peat consumption, Domestic oil deliveries, Import prices of oil, Consumer prices of principal oil products, Fuel prices for heat production, Fuel prices for electricity production, Carbon dioxide emissions, Total energy consumption by source and CO 2 -emissions, Electricity supply, Energy imports by country of origin in January-June 1999, Energy exports by recipient country in January-June 1999, Consumer prices of liquid fuels, Consumer prices of hard coal, natural gas and indigenous fuels, Average electricity price by type of consumer, Price of district heating by type of consumer, Excise taxes, value added taxes and fiscal charges and fees included in consumer prices of some energy sources and Energy taxes and precautionary stock fees on oil products

  4. Secret Sharing Schemes with a large number of players from Toric Varieties

    DEFF Research Database (Denmark)

    Hansen, Johan P.

    A general theory for constructing linear secret sharing schemes over a finite field $\\Fq$ from toric varieties is introduced. The number of players can be as large as $(q-1)^r-1$ for $r\\geq 1$. We present general methods for obtaining the reconstruction and privacy thresholds as well as conditions...... for multiplication on the associated secret sharing schemes. In particular we apply the method on certain toric surfaces. The main results are ideal linear secret sharing schemes where the number of players can be as large as $(q-1)^2-1$. We determine bounds for the reconstruction and privacy thresholds...

  5. The large break LOCA evaluation method with the simplified statistic approach

    International Nuclear Information System (INIS)

    Kamata, Shinya; Kubo, Kazuo

    2004-01-01

    USNRC published the Code Scaling, Applicability and Uncertainty (CSAU) evaluation methodology to large break LOCA which supported the revised rule for Emergency Core Cooling System performance in 1989. In USNRC regulatory guide 1.157, it is required that the peak cladding temperature (PCT) cannot exceed 2200deg F with high probability 95th percentile. In recent years, overseas countries have developed statistical methodology and best estimate code with the model which can provide more realistic simulation for the phenomena based on the CSAU evaluation methodology. In order to calculate PCT probability distribution by Monte Carlo trials, there are approaches such as the response surface technique using polynomials, the order statistics method, etc. For the purpose of performing rational statistic analysis, Mitsubishi Heavy Industries, LTD (MHI) tried to develop the statistic LOCA method using the best estimate LOCA code MCOBRA/TRAC and the simplified code HOTSPOT. HOTSPOT is a Monte Carlo heat conduction solver to evaluate the uncertainties of the significant fuel parameters at the PCT positions of the hot rod. The direct uncertainty sensitivity studies can be performed without the response surface because the Monte Carlo simulation for key parameters can be performed in short time using HOTSPOT. With regard to the parameter uncertainties, MHI established the treatment that the bounding conditions are given for LOCA boundary and plant initial conditions, the Monte Carlo simulation using HOTSPOT is applied to the significant fuel parameters. The paper describes the large break LOCA evaluation method with the simplified statistic approach and the results of the application of the method to the representative four-loop nuclear power plant. (author)

  6. Common pitfalls in statistical analysis: Absolute risk reduction, relative risk reduction, and number needed to treat

    Science.gov (United States)

    Ranganathan, Priya; Pramesh, C. S.; Aggarwal, Rakesh

    2016-01-01

    In the previous article in this series on common pitfalls in statistical analysis, we looked at the difference between risk and odds. Risk, which refers to the probability of occurrence of an event or outcome, can be defined in absolute or relative terms. Understanding what these measures represent is essential for the accurate interpretation of study results. PMID:26952180

  7. Prospectus: towards the development of high-fidelity models of wall turbulence at large Reynolds number.

    Science.gov (United States)

    Klewicki, J C; Chini, G P; Gibson, J F

    2017-03-13

    Recent and on-going advances in mathematical methods and analysis techniques, coupled with the experimental and computational capacity to capture detailed flow structure at increasingly large Reynolds numbers, afford an unprecedented opportunity to develop realistic models of high Reynolds number turbulent wall-flow dynamics. A distinctive attribute of this new generation of models is their grounding in the Navier-Stokes equations. By adhering to this challenging constraint, high-fidelity models ultimately can be developed that not only predict flow properties at high Reynolds numbers, but that possess a mathematical structure that faithfully captures the underlying flow physics. These first-principles models are needed, for example, to reliably manipulate flow behaviours at extreme Reynolds numbers. This theme issue of Philosophical Transactions of the Royal Society A provides a selection of contributions from the community of researchers who are working towards the development of such models. Broadly speaking, the research topics represented herein report on dynamical structure, mechanisms and transport; scale interactions and self-similarity; model reductions that restrict nonlinear interactions; and modern asymptotic theories. In this prospectus, the challenges associated with modelling turbulent wall-flows at large Reynolds numbers are briefly outlined, and the connections between the contributing papers are highlighted.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).

  8. On quantum statistics for ensembles with a finite number of particles

    International Nuclear Information System (INIS)

    Trifonov, Evgenii D

    2011-01-01

    The well-known Bose-Einstein and Fermi-Dirac quantum distributions can be considered as stationary solutions of kinetic equations for the mean occupation numbers in an ideal gas of an arbitrary finite number of identical particles. (methodological notes)

  9. Statistics

    International Nuclear Information System (INIS)

    2003-01-01

    For the year 2002, part of the figures shown in the tables of the Energy Review are partly preliminary. The annual statistics of the Energy Review also includes historical time-series over a longer period (see e.g. Energiatilastot 2001, Statistics Finland, Helsinki 2002). The applied energy units and conversion coefficients are shown in the inside back cover of the Review. Explanatory notes to the statistical tables can be found after tables and figures. The figures presents: Changes in GDP, energy consumption and electricity consumption, Carbon dioxide emissions from fossile fuels use, Coal consumption, Consumption of natural gas, Peat consumption, Domestic oil deliveries, Import prices of oil, Consumer prices of principal oil products, Fuel prices in heat production, Fuel prices in electricity production, Price of electricity by type of consumer, Average monthly spot prices at the Nord pool power exchange, Total energy consumption by source and CO 2 -emissions, Supply and total consumption of electricity GWh, Energy imports by country of origin in January-June 2003, Energy exports by recipient country in January-June 2003, Consumer prices of liquid fuels, Consumer prices of hard coal, natural gas and indigenous fuels, Price of natural gas by type of consumer, Price of electricity by type of consumer, Price of district heating by type of consumer, Excise taxes, value added taxes and fiscal charges and fees included in consumer prices of some energy sources and Excise taxes, precautionary stock fees on oil pollution fees on energy products

  10. Statistics

    International Nuclear Information System (INIS)

    2004-01-01

    For the year 2003 and 2004, the figures shown in the tables of the Energy Review are partly preliminary. The annual statistics of the Energy Review also includes historical time-series over a longer period (see e.g. Energiatilastot, Statistics Finland, Helsinki 2003, ISSN 0785-3165). The applied energy units and conversion coefficients are shown in the inside back cover of the Review. Explanatory notes to the statistical tables can be found after tables and figures. The figures presents: Changes in GDP, energy consumption and electricity consumption, Carbon dioxide emissions from fossile fuels use, Coal consumption, Consumption of natural gas, Peat consumption, Domestic oil deliveries, Import prices of oil, Consumer prices of principal oil products, Fuel prices in heat production, Fuel prices in electricity production, Price of electricity by type of consumer, Average monthly spot prices at the Nord pool power exchange, Total energy consumption by source and CO 2 -emissions, Supplies and total consumption of electricity GWh, Energy imports by country of origin in January-March 2004, Energy exports by recipient country in January-March 2004, Consumer prices of liquid fuels, Consumer prices of hard coal, natural gas and indigenous fuels, Price of natural gas by type of consumer, Price of electricity by type of consumer, Price of district heating by type of consumer, Excise taxes, value added taxes and fiscal charges and fees included in consumer prices of some energy sources and Excise taxes, precautionary stock fees on oil pollution fees

  11. Statistics

    International Nuclear Information System (INIS)

    2000-01-01

    For the year 1999 and 2000, part of the figures shown in the tables of the Energy Review are preliminary or estimated. The annual statistics of the Energy also includes historical time series over a longer period (see e.g., Energiatilastot 1999, Statistics Finland, Helsinki 2000, ISSN 0785-3165). The inside of the Review's back cover shows the energy units and the conversion coefficients used for them. Explanatory notes to the statistical tables can be found after tables and figures. The figures presents: Changes in the volume of GNP and energy consumption, Changes in the volume of GNP and electricity, Coal consumption, Natural gas consumption, Peat consumption, Domestic oil deliveries, Import prices of oil, Consumer prices of principal oil products, Fuel prices for heat production, Fuel prices for electricity production, Carbon dioxide emissions, Total energy consumption by source and CO 2 -emissions, Electricity supply, Energy imports by country of origin in January-June 2000, Energy exports by recipient country in January-June 2000, Consumer prices of liquid fuels, Consumer prices of hard coal, natural gas and indigenous fuels, Average electricity price by type of consumer, Price of district heating by type of consumer, Excise taxes, value added taxes and fiscal charges and fees included in consumer prices of some energy sources and Energy taxes and precautionary stock fees on oil products

  12. Scalar energy fluctuations in Large-Eddy Simulation of turbulent flames: Statistical budgets and mesh quality criterion

    Energy Technology Data Exchange (ETDEWEB)

    Vervisch, Luc; Domingo, Pascale; Lodato, Guido [CORIA - CNRS and INSA de Rouen, Technopole du Madrillet, BP 8, 76801 Saint-Etienne-du-Rouvray (France); Veynante, Denis [EM2C - CNRS and Ecole Centrale Paris, Grande Voie des Vignes, 92295 Chatenay-Malabry (France)

    2010-04-15

    Large-Eddy Simulation (LES) provides space-filtered quantities to compare with measurements, which usually have been obtained using a different filtering operation; hence, numerical and experimental results can be examined side-by-side in a statistical sense only. Instantaneous, space-filtered and statistically time-averaged signals feature different characteristic length-scales, which can be combined in dimensionless ratios. From two canonical manufactured turbulent solutions, a turbulent flame and a passive scalar turbulent mixing layer, the critical values of these ratios under which measured and computed variances (resolved plus sub-grid scale) can be compared without resorting to additional residual terms are first determined. It is shown that actual Direct Numerical Simulation can hardly accommodate a sufficiently large range of length-scales to perform statistical studies of LES filtered reactive scalar-fields energy budget based on sub-grid scale variances; an estimation of the minimum Reynolds number allowing for such DNS studies is given. From these developments, a reliability mesh criterion emerges for scalar LES and scaling for scalar sub-grid scale energy is discussed. (author)

  13. Obstructions to the realization of distance graphs with large chromatic numbers on spheres of small radii

    Energy Technology Data Exchange (ETDEWEB)

    Kupavskii, A B; Raigorodskii, A M [M. V. Lomonosov Moscow State University, Faculty of Mechanics and Mathematics, Moscow (Russian Federation)

    2013-10-31

    We investigate in detail some properties of distance graphs constructed on the integer lattice. Such graphs find wide applications in problems of combinatorial geometry, in particular, such graphs were employed to answer Borsuk's question in the negative and to obtain exponential estimates for the chromatic number of the space. This work is devoted to the study of the number of cliques and the chromatic number of such graphs under certain conditions. Constructions of sequences of distance graphs are given, in which the graphs have unit length edges and contain a large number of triangles that lie on a sphere of radius 1/√3 (which is the minimum possible). At the same time, the chromatic numbers of the graphs depend exponentially on their dimension. The results of this work strengthen and generalize some of the results obtained in a series of papers devoted to related issues. Bibliography: 29 titles.

  14. ON AN EXPONENTIAL INEQUALITY AND A STRONG LAW OF LARGE NUMBERS FOR MONOTONE MEASURES

    Czech Academy of Sciences Publication Activity Database

    Agahi, H.; Mesiar, Radko

    2014-01-01

    Roč. 50, č. 5 (2014), s. 804-813 ISSN 0023-5954 Institutional support: RVO:67985556 Keywords : Choquet expectation * a strong law of large numbers * exponential inequality * monotone probability Subject RIV: BA - General Mathematics Impact factor: 0.541, year: 2014 http://library.utia.cas.cz/separaty/2014/E/mesiar-0438052.pdf

  15. Strong Laws of Large Numbers for Arrays of Rowwise NA and LNQD Random Variables

    Directory of Open Access Journals (Sweden)

    Jiangfeng Wang

    2011-01-01

    Full Text Available Some strong laws of large numbers and strong convergence properties for arrays of rowwise negatively associated and linearly negative quadrant dependent random variables are obtained. The results obtained not only generalize the result of Hu and Taylor to negatively associated and linearly negative quadrant dependent random variables, but also improve it.

  16. The lore of large numbers: some historical background to the anthropic principle

    International Nuclear Information System (INIS)

    Barrow, J.D.

    1981-01-01

    A description is given of how the study of numerological coincidences in physics and cosmology led first to the Large Numbers Hypothesis of Dirac and then to the suggestion of the Anthropic Principle in a variety of forms. The early history of 'coincidences' is discussed together with the work of Weyl, Eddington and Dirac. (author)

  17. The three-large-primes variant of the number field sieve

    NARCIS (Netherlands)

    S.H. Cavallar

    2002-01-01

    textabstractThe Number Field Sieve (NFS) is the asymptotically fastest known factoringalgorithm for large integers.This method was proposed by John Pollard in 1988. Sincethen several variants have been implemented with the objective of improving thesiever which is the most time consuming part of

  18. SECRET SHARING SCHEMES WITH STRONG MULTIPLICATION AND A LARGE NUMBER OF PLAYERS FROM TORIC VARIETIES

    DEFF Research Database (Denmark)

    Hansen, Johan Peder

    2017-01-01

    This article consider Massey's construction for constructing linear secret sharing schemes from toric varieties over a finite field $\\Fq$ with $q$ elements. The number of players can be as large as $(q-1)^r-1$ for $r\\geq 1$. The schemes have strong multiplication, such schemes can be utilized in ...

  19. Statistical Modeling of the Trends Concerning the Number of Hospitals and Medical Centres in Romania

    Directory of Open Access Journals (Sweden)

    Gabriela OPAIT

    2017-04-01

    Full Text Available This study reveals the technique for to achive the shapes of the mathematical models which put in evidence the distributions of the values concerning the number of Hospitals, respectively Medical Centres, in our country, in the time horizon 2005-2014. In the same time, we can to observe the algorithm applied for to construct forecasts about the evolutions regarding the number of Hospitals and Medical Centres in Romania.

  20. Prospectus: towards the development of high-fidelity models of wall turbulence at large Reynolds number

    Science.gov (United States)

    Klewicki, J. C.; Chini, G. P.; Gibson, J. F.

    2017-01-01

    Recent and on-going advances in mathematical methods and analysis techniques, coupled with the experimental and computational capacity to capture detailed flow structure at increasingly large Reynolds numbers, afford an unprecedented opportunity to develop realistic models of high Reynolds number turbulent wall-flow dynamics. A distinctive attribute of this new generation of models is their grounding in the Navier–Stokes equations. By adhering to this challenging constraint, high-fidelity models ultimately can be developed that not only predict flow properties at high Reynolds numbers, but that possess a mathematical structure that faithfully captures the underlying flow physics. These first-principles models are needed, for example, to reliably manipulate flow behaviours at extreme Reynolds numbers. This theme issue of Philosophical Transactions of the Royal Society A provides a selection of contributions from the community of researchers who are working towards the development of such models. Broadly speaking, the research topics represented herein report on dynamical structure, mechanisms and transport; scale interactions and self-similarity; model reductions that restrict nonlinear interactions; and modern asymptotic theories. In this prospectus, the challenges associated with modelling turbulent wall-flows at large Reynolds numbers are briefly outlined, and the connections between the contributing papers are highlighted. This article is part of the themed issue ‘Toward the development of high-fidelity models of wall turbulence at large Reynolds number’. PMID:28167585

  1. Optimal number of coarse-grained sites in different components of large biomolecular complexes.

    Science.gov (United States)

    Sinitskiy, Anton V; Saunders, Marissa G; Voth, Gregory A

    2012-07-26

    The computational study of large biomolecular complexes (molecular machines, cytoskeletal filaments, etc.) is a formidable challenge facing computational biophysics and biology. To achieve biologically relevant length and time scales, coarse-grained (CG) models of such complexes usually must be built and employed. One of the important early stages in this approach is to determine an optimal number of CG sites in different constituents of a complex. This work presents a systematic approach to this problem. First, a universal scaling law is derived and numerically corroborated for the intensity of the intrasite (intradomain) thermal fluctuations as a function of the number of CG sites. Second, this result is used for derivation of the criterion for the optimal number of CG sites in different parts of a large multibiomolecule complex. In the zeroth-order approximation, this approach validates the empirical rule of taking one CG site per fixed number of atoms or residues in each biomolecule, previously widely used for smaller systems (e.g., individual biomolecules). The first-order corrections to this rule are derived and numerically checked by the case studies of the Escherichia coli ribosome and Arp2/3 actin filament junction. In different ribosomal proteins, the optimal number of amino acids per CG site is shown to differ by a factor of 3.5, and an even wider spread may exist in other large biomolecular complexes. Therefore, the method proposed in this paper is valuable for the optimal construction of CG models of such complexes.

  2. Calculation of large Reynolds number two-dimensional flow using discrete vortices with random walk

    International Nuclear Information System (INIS)

    Milinazzo, F.; Saffman, P.G.

    1977-01-01

    The numerical calculation of two-dimensional rotational flow at large Reynolds number is considered. The method of replacing a continuous distribution of vorticity by a finite number, N, of discrete vortices is examined, where the vortices move under their mutually induced velocities plus a random component to simulate effects of viscosity. The accuracy of the method is studied by comparison with the exact solution for the decay of a circular vortex. It is found, and analytical arguments are produced in support, that the quantitative error is significant unless N is large compared with a characteristic Reynolds number. The mutually induced velocities are calculated by both direct summation and by the ''cloud in cell'' technique. The latter method is found to produce comparable error and to be much faster

  3. Ship detection using STFT sea background statistical modeling for large-scale oceansat remote sensing image

    Science.gov (United States)

    Wang, Lixia; Pei, Jihong; Xie, Weixin; Liu, Jinyuan

    2018-03-01

    Large-scale oceansat remote sensing images cover a big area sea surface, which fluctuation can be considered as a non-stationary process. Short-Time Fourier Transform (STFT) is a suitable analysis tool for the time varying nonstationary signal. In this paper, a novel ship detection method using 2-D STFT sea background statistical modeling for large-scale oceansat remote sensing images is proposed. First, the paper divides the large-scale oceansat remote sensing image into small sub-blocks, and 2-D STFT is applied to each sub-block individually. Second, the 2-D STFT spectrum of sub-blocks is studied and the obvious different characteristic between sea background and non-sea background is found. Finally, the statistical model for all valid frequency points in the STFT spectrum of sea background is given, and the ship detection method based on the 2-D STFT spectrum modeling is proposed. The experimental result shows that the proposed algorithm can detect ship targets with high recall rate and low missing rate.

  4. 4P: fast computing of population genetics statistics from large DNA polymorphism panels.

    Science.gov (United States)

    Benazzo, Andrea; Panziera, Alex; Bertorelle, Giorgio

    2015-01-01

    Massive DNA sequencing has significantly increased the amount of data available for population genetics and molecular ecology studies. However, the parallel computation of simple statistics within and between populations from large panels of polymorphic sites is not yet available, making the exploratory analyses of a set or subset of data a very laborious task. Here, we present 4P (parallel processing of polymorphism panels), a stand-alone software program for the rapid computation of genetic variation statistics (including the joint frequency spectrum) from millions of DNA variants in multiple individuals and multiple populations. It handles a standard input file format commonly used to store DNA variation from empirical or simulation experiments. The computational performance of 4P was evaluated using large SNP (single nucleotide polymorphism) datasets from human genomes or obtained by simulations. 4P was faster or much faster than other comparable programs, and the impact of parallel computing using multicore computers or servers was evident. 4P is a useful tool for biologists who need a simple and rapid computer program to run exploratory population genetics analyses in large panels of genomic data. It is also particularly suitable to analyze multiple data sets produced in simulation studies. Unix, Windows, and MacOs versions are provided, as well as the source code for easier pipeline implementations.

  5. The Love of Large Numbers: A Popularity Bias in Consumer Choice.

    Science.gov (United States)

    Powell, Derek; Yu, Jingqi; DeWolf, Melissa; Holyoak, Keith J

    2017-10-01

    Social learning-the ability to learn from observing the decisions of other people and the outcomes of those decisions-is fundamental to human evolutionary and cultural success. The Internet now provides social evidence on an unprecedented scale. However, properly utilizing this evidence requires a capacity for statistical inference. We examined how people's interpretation of online review scores is influenced by the numbers of reviews-a potential indicator both of an item's popularity and of the precision of the average review score. Our task was designed to pit statistical information against social information. We modeled the behavior of an "intuitive statistician" using empirical prior information from millions of reviews posted on Amazon.com and then compared the model's predictions with the behavior of experimental participants. Under certain conditions, people preferred a product with more reviews to one with fewer reviews even though the statistical model indicated that the latter was likely to be of higher quality than the former. Overall, participants' judgments suggested that they failed to make meaningful statistical inferences.

  6. Statistics of an ideal homogeneous Bose gas with a fixed number of particles

    International Nuclear Information System (INIS)

    Alekseev, Vladimir A

    2001-01-01

    The distribution function w 0 (n 0 ) of the number n 0 of particles is found for the condensate of an ideal gas of free bosons with a fixed total number N of particles. It is shown that above the critical temperature (T > T c ) this function has the usual form w 0 (n 0 ) = (1 - e μ )e μn 0 , where μ is the chemical potential in temperature units. In a narrow vicinity of the critical temperature |T/T c - 1| ≤ N -1/3 , this distribution changes and at T c acquires the form of a resonance. The width of the resonance depends on the shape of the volume occupied by the gas and it has exponential (but not the Gaussian) wings. As the temperature is lowered, the resonance maximum shifts to larger values of n 0 and its width tends to zero, which corresponds to the suppression of fluctuations. For N → ∞, this change occurs abruptly. The distribution function of the number of particles in excited states for the systems with a fixed and a variable number of particles (when only a mean number of particles is fixed) prove to be identical and have the usual form. (physical basis of quantum electronics)

  7. Statistical inference of the nuclear accidents occurrence number for the next decade

    International Nuclear Information System (INIS)

    Felizia, E.R.

    1987-01-01

    This paper aims to give a response using the classical statistical and bayesian inference techniques regarding the common characteristic in the Harrisburg and Chernobyl nuclear accidents: in both reactors, core fusion occurred. In relation to the last mentioned techniques, the most recent developments were applied, based on the decision theory of uncertainty; among others, the principle of maximum entropy. Besides, as a preliminar information on the accidents occurrence frequency with core fusion, the German risk analysis results were used. The estimations predicted for the next decade an average between one or two accidents with core fusion and low possibilities for the 'no accident' event in the same period. (Author)

  8. Statistical methods for including two-body forces in large system calculations

    International Nuclear Information System (INIS)

    Grimes, S.M.

    1980-07-01

    Large systems of interacting particles are often treated by assuming that the effect on any one particle of the remaining N-1 may be approximated by an average potential. This approach reduces the problem to that of finding the bound-state solutions for a particle in a potential; statistical mechanics is then used to obtain the properties of the many-body system. In some physical systems this approach may not be acceptable, because the two-body force component cannot be treated in this one-body limit. A technique for incorporating two-body forces in such calculations in a more realistic fashion is described. 1 figure

  9. Advanced statistical tools for SNP arrays : signal calibration, copy number estimation and single array genotyping

    NARCIS (Netherlands)

    Rippe, Ralph Christian Alexander

    2012-01-01

    Fluorescence bias in in signals from individual SNP arrays can be calibrated using linear models. Given the data, the system of equations is very large, so a specialized symbolic algorithm was developed. These models are also used to illustrate that genomic waves do not exist, but are merely an

  10. Analyzing the Large Number of Variables in Biomedical and Satellite Imagery

    CERN Document Server

    Good, Phillip I

    2011-01-01

    This book grew out of an online interactive offered through statcourse.com, and it soon became apparent to the author that the course was too limited in terms of time and length in light of the broad backgrounds of the enrolled students. The statisticians who took the course needed to be brought up to speed both on the biological context as well as on the specialized statistical methods needed to handle large arrays. Biologists and physicians, even though fully knowledgeable concerning the procedures used to generate microaarrays, EEGs, or MRIs, needed a full introduction to the resampling met

  11. TRAN-STAT: (statistics for environmental studies), Number 23, April 1983

    International Nuclear Information System (INIS)

    Gilbert, R.O.; Simpson, J.C.

    1983-07-01

    Various statistical computing formulas have been used to estimate the transfer of radionuclides from one environmental component to another. The parameter being estimated is the ratio μ/sub V//μ/sub U/, where μ/sub U/ is the true mean concentration of the donor component (e.g., soil), and μ/sub V/ is the true mean concentration of the receiving component (e.g., vegetation). In radionuclide research μ/sub V//μ/sub U/ may be the concentration ratio (CR) or the inventory ratio (IR). A Monte Carlo computer simulation study in conjunction with mathematical derivations of bias and root expected mean square was conducted to provide guidance on which of eight estimators (computing formulae) are most likely to give the best estimate of μ/sub V//μ/sub U/. These estimators were evaluated for both laboratory and field studies when data are normally or lognormally distributed

  12. Statistical Modeling of Large-Scale Signal Path Loss in Underwater Acoustic Networks

    Directory of Open Access Journals (Sweden)

    Manuel Perez Malumbres

    2013-02-01

    Full Text Available In an underwater acoustic channel, the propagation conditions are known to vary in time, causing the deviation of the received signal strength from the nominal value predicted by a deterministic propagation model. To facilitate a large-scale system design in such conditions (e.g., power allocation, we have developed a statistical propagation model in which the transmission loss is treated as a random variable. By applying repetitive computation to the acoustic field, using ray tracing for a set of varying environmental conditions (surface height, wave activity, small node displacements around nominal locations, etc., an ensemble of transmission losses is compiled and later used to infer the statistical model parameters. A reasonable agreement is found with log-normal distribution, whose mean obeys a log-distance increases, and whose variance appears to be constant for a certain range of inter-node distances in a given deployment location. The statistical model is deemed useful for higher-level system planning, where simulation is needed to assess the performance of candidate network protocols under various resource allocation policies, i.e., to determine the transmit power and bandwidth allocation necessary to achieve a desired level of performance (connectivity, throughput, reliability, etc..

  13. Statistical Analyses of Scatterplots to Identify Important Factors in Large-Scale Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Kleijnen, J.P.C.; Helton, J.C.

    1999-04-01

    The robustness of procedures for identifying patterns in scatterplots generated in Monte Carlo sensitivity analyses is investigated. These procedures are based on attempts to detect increasingly complex patterns in the scatterplots under consideration and involve the identification of (1) linear relationships with correlation coefficients, (2) monotonic relationships with rank correlation coefficients, (3) trends in central tendency as defined by means, medians and the Kruskal-Wallis statistic, (4) trends in variability as defined by variances and interquartile ranges, and (5) deviations from randomness as defined by the chi-square statistic. The following two topics related to the robustness of these procedures are considered for a sequence of example analyses with a large model for two-phase fluid flow: the presence of Type I and Type II errors, and the stability of results obtained with independent Latin hypercube samples. Observations from analysis include: (1) Type I errors are unavoidable, (2) Type II errors can occur when inappropriate analysis procedures are used, (3) physical explanations should always be sought for why statistical procedures identify variables as being important, and (4) the identification of important variables tends to be stable for independent Latin hypercube samples.

  14. Statistical Image Properties in Large Subsets of Traditional Art, Bad Art, and Abstract Art.

    Science.gov (United States)

    Redies, Christoph; Brachmann, Anselm

    2017-01-01

    Several statistical image properties have been associated with large subsets of traditional visual artworks. Here, we investigate some of these properties in three categories of art that differ in artistic claim and prestige: (1) Traditional art of different cultural origin from established museums and art collections (oil paintings and graphic art of Western provenance, Islamic book illustration and Chinese paintings), (2) Bad Art from two museums that collect contemporary artworks of lesser importance (© Museum Of Bad Art [MOBA], Somerville, and Official Bad Art Museum of Art [OBAMA], Seattle), and (3) twentieth century abstract art of Western provenance from two prestigious museums (Tate Gallery and Kunstsammlung Nordrhein-Westfalen). We measured the following four statistical image properties: the fractal dimension (a measure relating to subjective complexity); self-similarity (a measure of how much the sections of an image resemble the image as a whole), 1st-order entropy of edge orientations (a measure of how uniformly different orientations are represented in an image); and 2nd-order entropy of edge orientations (a measure of how independent edge orientations are across an image). As shown previously, traditional artworks of different styles share similar values for these measures. The values for Bad Art and twentieth century abstract art show a considerable overlap with those of traditional art, but we also identified numerous examples of Bad Art and abstract art that deviate from traditional art. By measuring statistical image properties, we quantify such differences in image composition for the first time.

  15. Galaxies distribution in the universe: large-scale statistics and structures

    International Nuclear Information System (INIS)

    Maurogordato, Sophie

    1988-01-01

    This research thesis addresses the distribution of galaxies in the Universe, and more particularly large scale statistics and structures. Based on an assessment of the main used statistical techniques, the author outlines the need to develop additional tools to correlation functions in order to characterise the distribution. She introduces a new indicator: the probability of a volume randomly tested in the distribution to be void. This allows a characterisation of void properties at the work scales (until 10h"-"1 Mpc) in the Harvard Smithsonian Center for Astrophysics Redshift Survey, or CfA catalog. A systematic analysis of statistical properties of different sub-samples has then been performed with respect to the size and location, luminosity class, and morphological type. This analysis is then extended to different scenarios of structure formation. A program of radial speed measurements based on observations allows the determination of possible relationships between apparent structures. The author also presents results of the search for south extensions of Perseus supernova [fr

  16. The challenge for genetic epidemiologists: how to analyze large numbers of SNPs in relation to complex diseases.

    Science.gov (United States)

    Heidema, A Geert; Boer, Jolanda M A; Nagelkerke, Nico; Mariman, Edwin C M; van der A, Daphne L; Feskens, Edith J M

    2006-04-21

    Genetic epidemiologists have taken the challenge to identify genetic polymorphisms involved in the development of diseases. Many have collected data on large numbers of genetic markers but are not familiar with available methods to assess their association with complex diseases. Statistical methods have been developed for analyzing the relation between large numbers of genetic and environmental predictors to disease or disease-related variables in genetic association studies. In this commentary we discuss logistic regression analysis, neural networks, including the parameter decreasing method (PDM) and genetic programming optimized neural networks (GPNN) and several non-parametric methods, which include the set association approach, combinatorial partitioning method (CPM), restricted partitioning method (RPM), multifactor dimensionality reduction (MDR) method and the random forests approach. The relative strengths and weaknesses of these methods are highlighted. Logistic regression and neural networks can handle only a limited number of predictor variables, depending on the number of observations in the dataset. Therefore, they are less useful than the non-parametric methods to approach association studies with large numbers of predictor variables. GPNN on the other hand may be a useful approach to select and model important predictors, but its performance to select the important effects in the presence of large numbers of predictors needs to be examined. Both the set association approach and random forests approach are able to handle a large number of predictors and are useful in reducing these predictors to a subset of predictors with an important contribution to disease. The combinatorial methods give more insight in combination patterns for sets of genetic and/or environmental predictor variables that may be related to the outcome variable. As the non-parametric methods have different strengths and weaknesses we conclude that to approach genetic association

  17. Statistical identification with hidden Markov models of large order splitting strategies in an equity market

    Science.gov (United States)

    Vaglica, Gabriella; Lillo, Fabrizio; Mantegna, Rosario N.

    2010-07-01

    Large trades in a financial market are usually split into smaller parts and traded incrementally over extended periods of time. We address these large trades as hidden orders. In order to identify and characterize hidden orders, we fit hidden Markov models to the time series of the sign of the tick-by-tick inventory variation of market members of the Spanish Stock Exchange. Our methodology probabilistically detects trading sequences, which are characterized by a significant majority of buy or sell transactions. We interpret these patches of sequential buying or selling transactions as proxies of the traded hidden orders. We find that the time, volume and number of transaction size distributions of these patches are fat tailed. Long patches are characterized by a large fraction of market orders and a low participation rate, while short patches have a large fraction of limit orders and a high participation rate. We observe the existence of a buy-sell asymmetry in the number, average length, average fraction of market orders and average participation rate of the detected patches. The detected asymmetry is clearly dependent on the local market trend. We also compare the hidden Markov model patches with those obtained with the segmentation method used in Vaglica et al (2008 Phys. Rev. E 77 036110), and we conclude that the former ones can be interpreted as a partition of the latter ones.

  18. Break down of the law of large numbers in Josephson junction series arrays

    International Nuclear Information System (INIS)

    Dominguez, D.; Cerdeira, H.A.

    1995-01-01

    We study underdamped Josephson junction series arrays that are globally coupled through a resistive shunting load and driven by an rf bias current. We find that they can be an experimental realization of many phenomena currently studied in globally coupled logistic maps. We find coherent, ordered, partially ordered and turbulent phases in the IV characteristics of the array. The ordered phase corresponds to giant Shapiro steps. In the turbulent phase there is a saturation of the broad band noise for a large number of junctions. This corresponds to a break down of the law of large numbers as seen in globally coupled maps. Coexisting with this, we find an emergence of novel pseudo-steps in the IV characteristics. This effect can be experimentally distinguished from the true Shapiro steps, which do not have broad band noise emission. (author). 21 refs, 5 figs

  19. Breakdown of the law of large numbers in Josephson junction series arrays

    International Nuclear Information System (INIS)

    Dominguez, D.; Cerdeira, H.A.

    1994-01-01

    We study underdamped Josephson junction series arrays that are globally coupled through a resistive shunting load and driven by an rf bias current. We find that they can be an experimental realization of many phenomena currently studied in globally coupled logistic maps. We find coherent, ordered, partially ordered and turbulent phases in the IV characteristics of the array. The ordered phase corresponds to giant Shapiro steps. In the turbulent phase there is a saturation of the broad band noise for a large number of junctions. This corresponds to a break down of the law of large numbers as seen in the globally coupled maps. Coexisting with this, we find an emergence of novel pseudo-steps in the IV characteristics. This effect can be experimentally distinguished from the Shapiro steps, which do not have broad band noise emission. (author). 21 refs, 5 figs

  20. The holographic dual of a Riemann problem in a large number of dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Herzog, Christopher P.; Spillane, Michael [C.N. Yang Institute for Theoretical Physics, Department of Physics and Astronomy,Stony Brook University, Stony Brook, NY 11794 (United States); Yarom, Amos [Department of Physics, Technion,Haifa 32000 (Israel)

    2016-08-22

    We study properties of a non equilibrium steady state generated when two heat baths are initially in contact with one another. The dynamics of the system we study are governed by holographic duality in a large number of dimensions. We discuss the “phase diagram” associated with the steady state, the dual, dynamical, black hole description of this problem, and its relation to the fluid/gravity correspondence.

  1. Phases of a stack of membranes in a large number of dimensions of configuration space

    Science.gov (United States)

    Borelli, M. E.; Kleinert, H.

    2001-05-01

    The phase diagram of a stack of tensionless membranes with nonlinear curvature energy and vertical harmonic interaction is calculated exactly in a large number of dimensions of configuration space. At low temperatures, the system forms a lamellar phase with spontaneously broken translational symmetry in the vertical direction. At a critical temperature, the stack disorders vertically in a meltinglike transition. The critical temperature is determined as a function of the interlayer separation l.

  2. Early stage animal hoarders: are these owners of large numbers of adequately cared for cats?

    OpenAIRE

    Ramos, D.; da Cruz, N. O.; Ellis, Sarah; Hernandez, J. A. E.; Reche-Junior, A.

    2013-01-01

    Animal hoarding is a spectrum-based condition in which hoarders are often reported to have had normal and appropriate pet-keeping habits in childhood and early adulthood. Historically, research has focused largely on well established clinical animal hoarders with little work targeted towards the onset and development of animal hoarding. This study investigated whether a Brazilian population of owners of what might typically be considered an excessive number (20 or more) of cats were more like...

  3. Loss of locality in gravitational correlators with a large number of insertions

    Science.gov (United States)

    Ghosh, Sudip; Raju, Suvrat

    2017-09-01

    We review lessons from the AdS/CFT correspondence that indicate that the emergence of locality in quantum gravity is contingent upon considering observables with a small number of insertions. Correlation functions, where the number of insertions scales with a power of the central charge of the CFT, are sensitive to nonlocal effects in the bulk theory, which arise from a combination of the effects of the bulk Gauss law and a breakdown of perturbation theory. To examine whether a similar effect occurs in flat space, we consider the scattering of massless particles in the bosonic string and the superstring in the limit, where the number of external particles, n, becomes very large. We use estimates of the volume of the Weil-Petersson moduli space of punctured Riemann surfaces to argue that string amplitudes grow factorially in this limit. We verify this factorial behavior through an extensive numerical analysis of string amplitudes at large n. Our numerical calculations rely on the observation that, in the large n limit, the string scattering amplitude localizes on the Gross-Mende saddle points, even though individual particle energies are small. This factorial growth implies the breakdown of string perturbation theory for n ˜(M/plE ) d -2 in d dimensions, where E is the typical individual particle energy. We explore the implications of this breakdown for the black hole information paradox. We show that the loss of locality suggested by this breakdown is precisely sufficient to resolve the cloning and strong subadditivity paradoxes.

  4. A methodology for the synthesis of heat exchanger networks having large numbers of uncertain parameters

    International Nuclear Information System (INIS)

    Novak Pintarič, Zorka; Kravanja, Zdravko

    2015-01-01

    This paper presents a robust computational methodology for the synthesis and design of flexible HEN (Heat Exchanger Networks) having large numbers of uncertain parameters. This methodology combines several heuristic methods which progressively lead to a flexible HEN design at a specific level of confidence. During the first step, a HEN topology is generated under nominal conditions followed by determining those points critical for flexibility. A significantly reduced multi-scenario model for flexible HEN design is formulated at the nominal point with the flexibility constraints at the critical points. The optimal design obtained is tested by stochastic Monte Carlo optimization and the flexibility index through solving one-scenario problems within a loop. This presented methodology is novel regarding the enormous reduction of scenarios in HEN design problems, and computational effort. Despite several simplifications, the capability of designing flexible HENs with large numbers of uncertain parameters, which are typical throughout industry, is not compromised. An illustrative case study is presented for flexible HEN synthesis comprising 42 uncertain parameters. - Highlights: • Methodology for HEN (Heat Exchanger Network) design under uncertainty is presented. • The main benefit is solving HENs having large numbers of uncertain parameters. • Drastically reduced multi-scenario HEN design problem is formulated through several steps. • Flexibility of HEN is guaranteed at a specific level of confidence.

  5. A full picture of large lepton number asymmetries of the Universe

    Energy Technology Data Exchange (ETDEWEB)

    Barenboim, Gabriela [Departament de Física Teòrica and IFIC, Universitat de València-CSIC, C/ Dr. Moliner, 50, Burjassot, E-46100 Spain (Spain); Park, Wan-Il, E-mail: Gabriela.Barenboim@uv.es, E-mail: wipark@jbnu.ac.kr [Department of Science Education (Physics), Chonbuk National University, 567 Baekje-daero, Jeonju, 561-756 (Korea, Republic of)

    2017-04-01

    A large lepton number asymmetry of O(0.1−1) at present Universe might not only be allowed but also necessary for consistency among cosmological data. We show that, if a sizeable lepton number asymmetry were produced before the electroweak phase transition, the requirement for not producing too much baryon number asymmetry through sphalerons processes, forces the high scale lepton number asymmetry to be larger than about 03. Therefore a mild entropy release causing O(10-100) suppression of pre-existing particle density should take place, when the background temperature of the Universe is around T = O(10{sup −2}-10{sup 2}) GeV for a large but experimentally consistent asymmetry to be present today. We also show that such a mild entropy production can be obtained by the late-time decays of the saxion, constraining the parameters of the Peccei-Quinn sector such as the mass and the vacuum expectation value of the saxion field to be m {sub φ} ∼> O(10) TeV and φ{sub 0} ∼> O(10{sup 14}) GeV, respectively.

  6. Monitoring a large number of pesticides and transformation products in water samples from Spain and Italy.

    Science.gov (United States)

    Rousis, Nikolaos I; Bade, Richard; Bijlsma, Lubertus; Zuccato, Ettore; Sancho, Juan V; Hernandez, Felix; Castiglioni, Sara

    2017-07-01

    Assessing the presence of pesticides in environmental waters is particularly challenging because of the huge number of substances used which may end up in the environment. Furthermore, the occurrence of pesticide transformation products (TPs) and/or metabolites makes this task even harder. Most studies dealing with the determination of pesticides in water include only a small number of analytes and in many cases no TPs. The present study applied a screening method for the determination of a large number of pesticides and TPs in wastewater (WW) and surface water (SW) from Spain and Italy. Liquid chromatography coupled to high-resolution mass spectrometry (HRMS) was used to screen a database of 450 pesticides and TPs. Detection and identification were based on specific criteria, i.e. mass accuracy, fragmentation, and comparison of retention times when reference standards were available, or a retention time prediction model when standards were not available. Seventeen pesticides and TPs from different classes (fungicides, herbicides and insecticides) were found in WW in Italy and Spain, and twelve in SW. Generally, in both countries more compounds were detected in effluent WW than in influent WW, and in SW than WW. This might be due to the analytical sensitivity in the different matrices, but also to the presence of multiple sources of pollution. HRMS proved a good screening tool to determine a large number of substances in water and identify some priority compounds for further quantitative analysis. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. The use of test scores from large-scale assessment surveys: psychometric and statistical considerations

    Directory of Open Access Journals (Sweden)

    Henry Braun

    2017-11-01

    Full Text Available Abstract Background Economists are making increasing use of measures of student achievement obtained through large-scale survey assessments such as NAEP, TIMSS, and PISA. The construction of these measures, employing plausible value (PV methodology, is quite different from that of the more familiar test scores associated with assessments such as the SAT or ACT. These differences have important implications both for utilization and interpretation. Although much has been written about PVs, it appears that there are still misconceptions about whether and how to employ them in secondary analyses. Methods We address a range of technical issues, including those raised in a recent article that was written to inform economists using these databases. First, an extensive review of the relevant literature was conducted, with particular attention to key publications that describe the derivation and psychometric characteristics of such achievement measures. Second, a simulation study was carried out to compare the statistical properties of estimates based on the use of PVs with those based on other, commonly used methods. Results It is shown, through both theoretical analysis and simulation, that under fairly general conditions appropriate use of PV yields approximately unbiased estimates of model parameters in regression analyses of large scale survey data. The superiority of the PV methodology is particularly evident when measures of student achievement are employed as explanatory variables. Conclusions The PV methodology used to report student test performance in large scale surveys remains the state-of-the-art for secondary analyses of these databases.

  8. The increasing number of surgical procedures for female genital fistula in England: analysis of Hospital Episode Statistics (HES) data.

    Science.gov (United States)

    Ismail, S I M F

    2015-01-01

    The aim of this study was to describe the number and trend of surgical procedures for female genital fistula in England. An online search of Hospital Episode Statistics (HES) data was carried out. Data were available for the 4-year period from 2002-03 until 2005-06. The total number of surgical procedures carried out for female genital fistula steadily increased by 28.7% from 616 in 2002-03 to 793 in 2005-06. The number of surgical procedures performed for rectovaginal fistula exceeded the total number of surgical procedures carried out for vesicovaginal and urethrovaginal fistula in each year of the study period. This pattern needs to be monitored and investigated further.

  9. Large-eddy simulation of flow over a grooved cylinder up to transcritical Reynolds numbers

    KAUST Repository

    Cheng, W.

    2017-11-27

    We report wall-resolved large-eddy simulation (LES) of flow over a grooved cylinder up to the transcritical regime. The stretched-vortex subgrid-scale model is embedded in a general fourth-order finite-difference code discretization on a curvilinear mesh. In the present study grooves are equally distributed around the circumference of the cylinder, each of sinusoidal shape with height , invariant in the spanwise direction. Based on the two parameters, and the Reynolds number where is the free-stream velocity, the diameter of the cylinder and the kinematic viscosity, two main sets of simulations are described. The first set varies from to while fixing . We study the flow deviation from the smooth-cylinder case, with emphasis on several important statistics such as the length of the mean-flow recirculation bubble , the pressure coefficient , the skin-friction coefficient and the non-dimensional pressure gradient parameter . It is found that, with increasing at fixed , some properties of the mean flow behave somewhat similarly to changes in the smooth-cylinder flow when is increased. This includes shrinking and nearly constant minimum pressure coefficient. In contrast, while the non-dimensional pressure gradient parameter remains nearly constant for the front part of the smooth cylinder flow, shows an oscillatory variation for the grooved-cylinder case. The second main set of LES varies from to with fixed . It is found that this range spans the subcritical and supercritical regimes and reaches the beginning of the transcritical flow regime. Mean-flow properties are diagnosed and compared with available experimental data including and the drag coefficient . The timewise variation of the lift and drag coefficients are also studied to elucidate the transition among three regimes. Instantaneous images of the surface, skin-friction vector field and also of the three-dimensional Q-criterion field are utilized to further understand the dynamics of the near-surface flow

  10. Solving Large-Scale Computational Problems Using Insights from Statistical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Selman, Bart [Cornell University

    2012-02-29

    Many challenging problems in computer science and related fields can be formulated as constraint satisfaction problems. Such problems consist of a set of discrete variables and a set of constraints between those variables, and represent a general class of so-called NP-complete problems. The goal is to find a value assignment to the variables that satisfies all constraints, generally requiring a search through and exponentially large space of variable-value assignments. Models for disordered systems, as studied in statistical physics, can provide important new insights into the nature of constraint satisfaction problems. Recently, work in this area has resulted in the discovery of a new method for solving such problems, called the survey propagation (SP) method. With SP, we can solve problems with millions of variables and constraints, an improvement of two orders of magnitude over previous methods.

  11. Statistical distribution of the local purity in a large quantum system

    International Nuclear Information System (INIS)

    De Pasquale, A; Pascazio, S; Facchi, P; Giovannetti, V; Parisi, G; Scardicchio, A

    2012-01-01

    The local purity of large many-body quantum systems can be studied by following a statistical mechanical approach based on a random matrix model. Restricting the analysis to the case of global pure states, this method proved to be successful, and a full characterization of the statistical properties of the local purity was obtained by computing the partition function of the problem. Here we generalize these techniques to the case of global mixed states. In this context, by uniformly sampling the phase space of states with assigned global mixedness, we determine the exact expression of the first two moments of the local purity and a general expression for the moments of higher order. This generalizes previous results obtained for globally pure configurations. Furthermore, through the introduction of a partition function for a suitable canonical ensemble, we compute the approximate expression of the first moment of the marginal purity in the high-temperature regime. In the process, we establish a formal connection with the theory of quantum twirling maps that provides an alternative, possibly fruitful, way of performing the calculation. (paper)

  12. Large scale statistical inference of signaling pathways from RNAi and microarray data

    Directory of Open Access Journals (Sweden)

    Poustka Annemarie

    2007-10-01

    Full Text Available Abstract Background The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray technology this enables researchers to gain insights into signaling pathways by observing downstream effects of individual knock-downs on gene expression. These secondary effects can be used to computationally reverse engineer features of the upstream signaling pathway. Results In this paper we address this challenging problem by extending previous work by Markowetz et al., who proposed a statistical framework to score networks hypotheses in a Bayesian manner. Our extensions go in three directions: First, we introduce a way to omit the data discretization step needed in the original framework via a calculation based on p-values instead. Second, we show how prior assumptions on the network structure can be incorporated into the scoring scheme using regularization techniques. Third and most important, we propose methods to scale up the original approach, which is limited to around 5 genes, to large scale networks. Conclusion Comparisons of these methods on artificial data are conducted. Our proposed module network is employed to infer the signaling network between 13 genes in the ER-α pathway in human MCF-7 breast cancer cells. Using a bootstrapping approach this reconstruction can be found with good statistical stability. The code for the module network inference method is available in the latest version of the R-package nem, which can be obtained from the Bioconductor homepage.

  13. Large scale Direct Numerical Simulation of premixed turbulent jet flames at high Reynolds number

    Science.gov (United States)

    Attili, Antonio; Luca, Stefano; Lo Schiavo, Ermanno; Bisetti, Fabrizio; Creta, Francesco

    2016-11-01

    A set of direct numerical simulations of turbulent premixed jet flames at different Reynolds and Karlovitz numbers is presented. The simulations feature finite rate chemistry with 16 species and 73 reactions and up to 22 Billion grid points. The jet consists of a methane/air mixture with equivalence ratio ϕ = 0 . 7 and temperature varying between 500 and 800 K. The temperature and species concentrations in the coflow correspond to the equilibrium state of the burnt mixture. All the simulations are performed at 4 atm. The flame length, normalized by the jet width, decreases significantly as the Reynolds number increases. This is consistent with an increase of the turbulent flame speed due to the increased integral scale of turbulence. This behavior is typical of flames in the thin-reaction zone regime, which are affected by turbulent transport in the preheat layer. Fractal dimension and topology of the flame surface, statistics of temperature gradients, and flame structure are investigated and the dependence of these quantities on the Reynolds number is assessed.

  14. Statistics on the parameters of nonisothermal ionospheric plasma in large mesospheric electric fields

    Science.gov (United States)

    Martynenko, S.; Rozumenko, V.; Tyrnov, O.; Manson, A.; Meek, C.

    The large V/m electric fields inherent in the mesosphere play an essential role in lower ionospheric electrodynamics. They must be the cause of large variations in the electron temperature and the electron collision frequency at D region altitudes, and consequently the ionospheric plasma in the lower part of the D region undergoes a transition into a nonisothermal state. This study is based on the databases on large mesospheric electric fields collected with the 2.2-MHz radar of the Institute of Space and Atmospheric Studies, University of Saskatchewan, Canada (52°N geographic latitude, 60.4°N geomagnetic latitude) and with the 2.3-MHz radar of the Kharkiv V. Karazin National University (49.6°N geographic latitude, 45.6°N geomagnetic latitude). The statistical analysis of these data is presented in Meek, C. E., A. H. Manson, S. I. Martynenko, V. T. Rozumenko, O. F. Tyrnov, Remote sensing of mesospheric electric fields using MF radars, Journal of Atmospheric and Solar-Terrestrial Physics, in press. The large mesospheric electric fields is experimentally established to follow a Rayleigh distribution in the interval 0

  15. Effects of baryons on the statistical properties of large scale structure of the Universe

    International Nuclear Information System (INIS)

    Guillet, T.

    2010-01-01

    Observations of weak gravitational lensing will provide strong constraints on the cosmic expansion history and the growth rate of large scale structure, yielding clues to the properties and nature of dark energy. Their interpretation is impacted by baryonic physics, which are expected to modify the total matter distribution at small scales. My work has focused on determining and modeling the impact of baryons on the statistics of the large scale matter distribution in the Universe. Using numerical simulations, I have extracted the effect of baryons on the power spectrum, variance and skewness of the total density field as predicted by these simulations. I have shown that a model based on the halo model construction, featuring a concentrated central component to account for cool condensed baryons, is able to reproduce accurately, and down to very small scales, the measured amplifications of both the variance and skewness of the density field. Because of well-known issues with baryons in current cosmological simulations, I have extended the central component model to rely on as many observation-based ingredients as possible. As an application, I have studied the effect of baryons on the predictions of the upcoming Euclid weak lensing survey. During the course of this work, I have also worked at developing and extending the RAMSES code, in particular by developing a parallel self-gravity solver, which offers significant performance gains, in particular for the simulation of some astrophysical setups such as isolated galaxy or cluster simulations. (author) [fr

  16. Impact factors for Reggeon-gluon transition in N=4 SYM with large number of colours

    Energy Technology Data Exchange (ETDEWEB)

    Fadin, V.S., E-mail: fadin@inp.nsk.su [Budker Institute of Nuclear Physics of SD RAS, 630090 Novosibirsk (Russian Federation); Novosibirsk State University, 630090 Novosibirsk (Russian Federation); Fiore, R., E-mail: roberto.fiore@cs.infn.it [Dipartimento di Fisica, Università della Calabria, and Istituto Nazionale di Fisica Nucleare, Gruppo collegato di Cosenza, Arcavacata di Rende, I-87036 Cosenza (Italy)

    2014-06-27

    We calculate impact factors for Reggeon-gluon transition in supersymmetric Yang–Mills theory with four supercharges at large number of colours N{sub c}. In the next-to-leading order impact factors are not uniquely defined and must accord with BFKL kernels and energy scales. We obtain the impact factor corresponding to the kernel and the energy evolution parameter, which is invariant under Möbius transformation in momentum space, and show that it is also Möbius invariant up to terms taken into account in the BDS ansatz.

  17. Do neutron stars disprove multiplicative creation in Dirac's large number hypothesis

    International Nuclear Information System (INIS)

    Qadir, A.; Mufti, A.A.

    1980-07-01

    Dirac's cosmology, based on his large number hypothesis, took the gravitational coupling to be decreasing with time and matter to be created as the square of time. Since the effects predicted by Dirac's theory are very small, it is difficult to find a ''clean'' test for it. Here we show that the observed radiation from pulsars is inconsistent with Dirac's multiplicative creation model, in which the matter created is proportional to the density of matter already present. Of course, this discussion makes no comment on the ''additive creation'' model, or on the revised version of Dirac's theory. (author)

  18. Law of large numbers and central limit theorem for randomly forced PDE's

    CERN Document Server

    Shirikyan, A

    2004-01-01

    We consider a class of dissipative PDE's perturbed by an external random force. Under the condition that the distribution of perturbation is sufficiently non-degenerate, a strong law of large numbers (SLLN) and a central limit theorem (CLT) for solutions are established and the corresponding rates of convergence are estimated. It is also shown that the estimates obtained are close to being optimal. The proofs are based on the property of exponential mixing for the problem in question and some abstract SLLN and CLT for mixing-type Markov processes.

  19. On the Convergence and Law of Large Numbers for the Non-Euclidean Lp -Means

    Directory of Open Access Journals (Sweden)

    George Livadiotis

    2017-05-01

    Full Text Available This paper describes and proves two important theorems that compose the Law of Large Numbers for the non-Euclidean L p -means, known to be true for the Euclidean L 2 -means: Let the L p -mean estimator, which constitutes the specific functional that estimates the L p -mean of N independent and identically distributed random variables; then, (i the expectation value of the L p -mean estimator equals the mean of the distributions of the random variables; and (ii the limit N → ∞ of the L p -mean estimator also equals the mean of the distributions.

  20. Calculating Confidence, Uncertainty, and Numbers of Samples When Using Statistical Sampling Approaches to Characterize and Clear Contaminated Areas

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, Gregory F.; Matzke, Brett D.; Sego, Landon H.; Amidan, Brett G.

    2013-04-27

    This report discusses the methodology, formulas, and inputs needed to make characterization and clearance decisions for Bacillus anthracis-contaminated and uncontaminated (or decontaminated) areas using a statistical sampling approach. Specifically, the report includes the methods and formulas for calculating the • number of samples required to achieve a specified confidence in characterization and clearance decisions • confidence in making characterization and clearance decisions for a specified number of samples for two common statistically based environmental sampling approaches. In particular, the report addresses an issue raised by the Government Accountability Office by providing methods and formulas to calculate the confidence that a decision area is uncontaminated (or successfully decontaminated) if all samples collected according to a statistical sampling approach have negative results. Key to addressing this topic is the probability that an individual sample result is a false negative, which is commonly referred to as the false negative rate (FNR). The two statistical sampling approaches currently discussed in this report are 1) hotspot sampling to detect small isolated contaminated locations during the characterization phase, and 2) combined judgment and random (CJR) sampling during the clearance phase. Typically if contamination is widely distributed in a decision area, it will be detectable via judgment sampling during the characterization phrase. Hotspot sampling is appropriate for characterization situations where contamination is not widely distributed and may not be detected by judgment sampling. CJR sampling is appropriate during the clearance phase when it is desired to augment judgment samples with statistical (random) samples. The hotspot and CJR statistical sampling approaches are discussed in the report for four situations: 1. qualitative data (detect and non-detect) when the FNR = 0 or when using statistical sampling methods that account

  1. Superposition of elliptic functions as solutions for a large number of nonlinear equations

    International Nuclear Information System (INIS)

    Khare, Avinash; Saxena, Avadh

    2014-01-01

    For a large number of nonlinear equations, both discrete and continuum, we demonstrate a kind of linear superposition. We show that whenever a nonlinear equation admits solutions in terms of both Jacobi elliptic functions cn(x, m) and dn(x, m) with modulus m, then it also admits solutions in terms of their sum as well as difference. We have checked this in the case of several nonlinear equations such as the nonlinear Schrödinger equation, MKdV, a mixed KdV-MKdV system, a mixed quadratic-cubic nonlinear Schrödinger equation, the Ablowitz-Ladik equation, the saturable nonlinear Schrödinger equation, λϕ 4 , the discrete MKdV as well as for several coupled field equations. Further, for a large number of nonlinear equations, we show that whenever a nonlinear equation admits a periodic solution in terms of dn 2 (x, m), it also admits solutions in terms of dn 2 (x,m)±√(m) cn (x,m) dn (x,m), even though cn(x, m)dn(x, m) is not a solution of these nonlinear equations. Finally, we also obtain superposed solutions of various forms for several coupled nonlinear equations

  2. Wall modeled large eddy simulations of complex high Reynolds number flows with synthetic inlet turbulence

    International Nuclear Information System (INIS)

    Patil, Sunil; Tafti, Danesh

    2012-01-01

    Highlights: ► Large eddy simulation. ► Wall layer modeling. ► Synthetic inlet turbulence. ► Swirl flows. - Abstract: Large eddy simulations of complex high Reynolds number flows are carried out with the near wall region being modeled with a zonal two layer model. A novel formulation for solving the turbulent boundary layer equation for the effective tangential velocity in a generalized co-ordinate system is presented and applied in the near wall zonal treatment. This formulation reduces the computational time in the inner layer significantly compared to the conventional two layer formulations present in the literature and is most suitable for complex geometries involving body fitted structured and unstructured meshes. The cost effectiveness and accuracy of the proposed wall model, used with the synthetic eddy method (SEM) to generate inlet turbulence, is investigated in turbulent channel flow, flow over a backward facing step, and confined swirling flows at moderately high Reynolds numbers. Predictions are compared with available DNS, experimental LDV data, as well as wall resolved LES. In all cases, there is at least an order of magnitude reduction in computational cost with no significant loss in prediction accuracy.

  3. Factors associated with self-reported number of teeth in a large national cohort of Thai adults

    Directory of Open Access Journals (Sweden)

    Yiengprugsawan Vasoontara

    2011-11-01

    Full Text Available Abstract Background Oral health in later life results from individual's lifelong accumulation of experiences at the personal, community and societal levels. There is little information relating the oral health outcomes to risk factors in Asian middle-income settings such as Thailand today. Methods Data derived from a cohort of 87,134 adults enrolled in Sukhothai Thammathirat Open University who completed self-administered questionnaires in 2005. Cohort members are aged between 15 and 87 years and resided throughout Thailand. This is a large study of self-reported number of teeth among Thai adults. Bivariate and multivariate logistic regressions were used to analyse factors associated with self-reported number of teeth. Results After adjusting for covariates, being female (OR = 1.28, older age (OR = 10.6, having low income (OR = 1.45, having lower education (OR = 1.33, and being a lifetime urban resident (OR = 1.37 were statistically associated (p Conclusions This study addresses the gap in knowledge on factors associated with self-reported number of teeth. The promotion of healthy childhoods and adult lifestyles are important public health interventions to increase tooth retention in middle and older age.

  4. Statistical analyses of digital collections: Using a large corpus of systematic reviews to study non-citations

    DEFF Research Database (Denmark)

    Frandsen, Tove Faber; Nicolaisen, Jeppe

    2017-01-01

    Using statistical methods to analyse digital material for patterns makes it possible to detect patterns in big data that we would otherwise not be able to detect. This paper seeks to exemplify this fact by statistically analysing a large corpus of references in systematic reviews. The aim...

  5. Conformal window in QCD for large numbers of colors and flavors

    International Nuclear Information System (INIS)

    Zhitnitsky, Ariel R.

    2014-01-01

    We conjecture that the phase transitions in QCD at large number of colors N≫1 is triggered by the drastic change in the instanton density. As a result of it, all physical observables also experience some sharp modification in the θ behavior. This conjecture is motivated by the holographic model of QCD where confinement–deconfinement phase transition indeed happens precisely at temperature T=T c where θ-dependence of the vacuum energy experiences a sudden change in behavior: from N 2 cos(θ/N) at T c to cosθexp(−N) at T>T c . This conjecture is also supported by recent lattice studies. We employ this conjecture to study a possible phase transition as a function of κ≡N f /N from confinement to conformal phase in the Veneziano limit N f ∼N when number of flavors and colors are large, but the ratio κ is finite. Technically, we consider an operator which gets its expectation value solely from non-perturbative instanton effects. When κ exceeds some critical value κ>κ c the integral over instanton size is dominated by small-size instantons, making the instanton computations reliable with expected exp(−N) behavior. However, when κ c , the integral over instanton size is dominated by large-size instantons, and the instanton expansion breaks down. This regime with κ c corresponds to the confinement phase. We also compute the variation of the critical κ c (T,μ) when the temperature and chemical potential T,μ≪Λ QCD slightly vary. We also discuss the scaling (x i −x j ) −γ det in the conformal phase

  6. Vicious random walkers in the limit of a large number of walkers

    International Nuclear Information System (INIS)

    Forrester, P.J.

    1989-01-01

    The vicious random walker problem on a line is studied in the limit of a large number of walkers. The multidimensional integral representing the probability that the p walkers will survive a time t (denoted P t (p) ) is shown to be analogous to the partition function of a particular one-component Coulomb gas. By assuming the existence of the thermodynamic limit for the Coulomb gas, one can deduce asymptotic formulas for P t (p) in the large-p, large-t limit. A straightforward analysis gives rigorous asymptotic formulas for the probability that after a time t the walkers are in their initial configuration (this event is termed a reunion). Consequently, asymptotic formulas for the conditional probability of a reunion, given that all walkers survive, are derived. Also, an asymptotic formula for the conditional probability density that any walker will arrive at a particular point in time t, given that all p walkers survive, is calculated in the limit t >> p

  7. Automated flow cytometric analysis across large numbers of samples and cell types.

    Science.gov (United States)

    Chen, Xiaoyi; Hasan, Milena; Libri, Valentina; Urrutia, Alejandra; Beitz, Benoît; Rouilly, Vincent; Duffy, Darragh; Patin, Étienne; Chalmond, Bernard; Rogge, Lars; Quintana-Murci, Lluis; Albert, Matthew L; Schwikowski, Benno

    2015-04-01

    Multi-parametric flow cytometry is a key technology for characterization of immune cell phenotypes. However, robust high-dimensional post-analytic strategies for automated data analysis in large numbers of donors are still lacking. Here, we report a computational pipeline, called FlowGM, which minimizes operator input, is insensitive to compensation settings, and can be adapted to different analytic panels. A Gaussian Mixture Model (GMM)-based approach was utilized for initial clustering, with the number of clusters determined using Bayesian Information Criterion. Meta-clustering in a reference donor permitted automated identification of 24 cell types across four panels. Cluster labels were integrated into FCS files, thus permitting comparisons to manual gating. Cell numbers and coefficient of variation (CV) were similar between FlowGM and conventional gating for lymphocyte populations, but notably FlowGM provided improved discrimination of "hard-to-gate" monocyte and dendritic cell (DC) subsets. FlowGM thus provides rapid high-dimensional analysis of cell phenotypes and is amenable to cohort studies. Copyright © 2015. Published by Elsevier Inc.

  8. Efficient statistically accurate algorithms for the Fokker-Planck equation in large dimensions

    Science.gov (United States)

    Chen, Nan; Majda, Andrew J.

    2018-02-01

    Solving the Fokker-Planck equation for high-dimensional complex turbulent dynamical systems is an important and practical issue. However, most traditional methods suffer from the curse of dimensionality and have difficulties in capturing the fat tailed highly intermittent probability density functions (PDFs) of complex systems in turbulence, neuroscience and excitable media. In this article, efficient statistically accurate algorithms are developed for solving both the transient and the equilibrium solutions of Fokker-Planck equations associated with high-dimensional nonlinear turbulent dynamical systems with conditional Gaussian structures. The algorithms involve a hybrid strategy that requires only a small number of ensembles. Here, a conditional Gaussian mixture in a high-dimensional subspace via an extremely efficient parametric method is combined with a judicious non-parametric Gaussian kernel density estimation in the remaining low-dimensional subspace. Particularly, the parametric method provides closed analytical formulae for determining the conditional Gaussian distributions in the high-dimensional subspace and is therefore computationally efficient and accurate. The full non-Gaussian PDF of the system is then given by a Gaussian mixture. Different from traditional particle methods, each conditional Gaussian distribution here covers a significant portion of the high-dimensional PDF. Therefore a small number of ensembles is sufficient to recover the full PDF, which overcomes the curse of dimensionality. Notably, the mixture distribution has significant skill in capturing the transient behavior with fat tails of the high-dimensional non-Gaussian PDFs, and this facilitates the algorithms in accurately describing the intermittency and extreme events in complex turbulent systems. It is shown in a stringent set of test problems that the method only requires an order of O (100) ensembles to successfully recover the highly non-Gaussian transient PDFs in up to 6

  9. Properties of sound attenuation around a two-dimensional underwater vehicle with a large cavitation number

    International Nuclear Information System (INIS)

    Ye Peng-Cheng; Pan Guang

    2015-01-01

    Due to the high speed of underwater vehicles, cavitation is generated inevitably along with the sound attenuation when the sound signal traverses through the cavity region around the underwater vehicle. The linear wave propagation is studied to obtain the influence of bubbly liquid on the acoustic wave propagation in the cavity region. The sound attenuation coefficient and the sound speed formula of the bubbly liquid are presented. Based on the sound attenuation coefficients with various vapor volume fractions, the attenuation of sound intensity is calculated under large cavitation number conditions. The result shows that the sound intensity attenuation is fairly small in a certain condition. Consequently, the intensity attenuation can be neglected in engineering. (paper)

  10. Random number generators for large-scale parallel Monte Carlo simulations on FPGA

    Science.gov (United States)

    Lin, Y.; Wang, F.; Liu, B.

    2018-05-01

    Through parallelization, field programmable gate array (FPGA) can achieve unprecedented speeds in large-scale parallel Monte Carlo (LPMC) simulations. FPGA presents both new constraints and new opportunities for the implementations of random number generators (RNGs), which are key elements of any Monte Carlo (MC) simulation system. Using empirical and application based tests, this study evaluates all of the four RNGs used in previous FPGA based MC studies and newly proposed FPGA implementations for two well-known high-quality RNGs that are suitable for LPMC studies on FPGA. One of the newly proposed FPGA implementations: a parallel version of additive lagged Fibonacci generator (Parallel ALFG) is found to be the best among the evaluated RNGs in fulfilling the needs of LPMC simulations on FPGA.

  11. Large-Eddy Simulation of a High Reynolds Number Flow Around a Cylinder Including Aeroacoustic Predictions

    Science.gov (United States)

    Spyropoulos, Evangelos T.; Holmes, Bayard S.

    1997-01-01

    The dynamic subgrid-scale model is employed in large-eddy simulations of flow over a cylinder at a Reynolds number, based on the diameter of the cylinder, of 90,000. The Centric SPECTRUM(trademark) finite element solver is used for the analysis. The far field sound pressure is calculated from Lighthill-Curle's equation using the computed fluctuating pressure at the surface of the cylinder. The sound pressure level at a location 35 diameters away from the cylinder and at an angle of 90 deg with respect to the wake's downstream axis was found to have a peak value of approximately 110 db. Slightly smaller peak values were predicted at the 60 deg and 120 deg locations. A grid refinement study suggests that the dynamic model demands mesh refinement beyond that used here.

  12. System for high-voltage control detectors with large number photomultipliers

    International Nuclear Information System (INIS)

    Donskov, S.V.; Kachanov, V.A.; Mikhajlov, Yu.V.

    1985-01-01

    A simple and inexpensive on-line system for hihg-voltage control which is designed for detectors with a large number of photomultipliers is developed and manufactured. It has been developed for the GAMC type hodoscopic electromagnetic calorimeters, comprising up to 4 thousand photomultipliers. High voltage variation is performed by a high-speed potentiometer which is rotated by a microengine. Block-diagrams of computer control electronics are presented. The high-voltage control system has been used for five years in the IHEP and CERN accelerator experiments. The operation experience has shown that it is quite simple and convenient in operation. In case of about 6 thousand controlled channels in both experiments no potentiometer and microengines failures were observed

  13. Statistical process control charts for attribute data involving very large sample sizes: a review of problems and solutions.

    Science.gov (United States)

    Mohammed, Mohammed A; Panesar, Jagdeep S; Laney, David B; Wilson, Richard

    2013-04-01

    The use of statistical process control (SPC) charts in healthcare is increasing. The primary purpose of SPC is to distinguish between common-cause variation which is attributable to the underlying process, and special-cause variation which is extrinsic to the underlying process. This is important because improvement under common-cause variation requires action on the process, whereas special-cause variation merits an investigation to first find the cause. Nonetheless, when dealing with attribute or count data (eg, number of emergency admissions) involving very large sample sizes, traditional SPC charts often produce tight control limits with most of the data points appearing outside the control limits. This can give a false impression of common and special-cause variation, and potentially misguide the user into taking the wrong actions. Given the growing availability of large datasets from routinely collected databases in healthcare, there is a need to present a review of this problem (which arises because traditional attribute charts only consider within-subgroup variation) and its solutions (which consider within and between-subgroup variation), which involve the use of the well-established measurements chart and the more recently developed attribute charts based on Laney's innovative approach. We close by making some suggestions for practice.

  14. Computational domain length and Reynolds number effects on large-scale coherent motions in turbulent pipe flow

    Science.gov (United States)

    Feldmann, Daniel; Bauer, Christian; Wagner, Claus

    2018-03-01

    We present results from direct numerical simulations (DNS) of turbulent pipe flow at shear Reynolds numbers up to Reτ = 1500 using different computational domains with lengths up to ?. The objectives are to analyse the effect of the finite size of the periodic pipe domain on large flow structures in dependency of Reτ and to assess a minimum ? required for relevant turbulent scales to be captured and a minimum Reτ for very large-scale motions (VLSM) to be analysed. Analysing one-point statistics revealed that the mean velocity profile is invariant for ?. The wall-normal location at which deviations occur in shorter domains changes strongly with increasing Reτ from the near-wall region to the outer layer, where VLSM are believed to live. The root mean square velocity profiles exhibit domain length dependencies for pipes shorter than 14R and 7R depending on Reτ. For all Reτ, the higher-order statistical moments show only weak dependencies and only for the shortest domain considered here. However, the analysis of one- and two-dimensional pre-multiplied energy spectra revealed that even for larger ?, not all physically relevant scales are fully captured, even though the aforementioned statistics are in good agreement with the literature. We found ? to be sufficiently large to capture VLSM-relevant turbulent scales in the considered range of Reτ based on our definition of an integral energy threshold of 10%. The requirement to capture at least 1/10 of the global maximum energy level is justified by a 14% increase of the streamwise turbulence intensity in the outer region between Reτ = 720 and 1500, which can be related to VLSM-relevant length scales. Based on this scaling anomaly, we found Reτ⪆1500 to be a necessary minimum requirement to investigate VLSM-related effects in pipe flow, even though the streamwise energy spectra does not yet indicate sufficient scale separation between the most energetic and the very long motions.

  15. Chaotic advection at large Péclet number: Electromagnetically driven experiments, numerical simulations, and theoretical predictions

    International Nuclear Information System (INIS)

    Figueroa, Aldo; Meunier, Patrice; Villermaux, Emmanuel; Cuevas, Sergio; Ramos, Eduardo

    2014-01-01

    We present a combination of experiment, theory, and modelling on laminar mixing at large Péclet number. The flow is produced by oscillating electromagnetic forces in a thin electrolytic fluid layer, leading to oscillating dipoles, quadrupoles, octopoles, and disordered flows. The numerical simulations are based on the Diffusive Strip Method (DSM) which was recently introduced (P. Meunier and E. Villermaux, “The diffusive strip method for scalar mixing in two-dimensions,” J. Fluid Mech. 662, 134–172 (2010)) to solve the advection-diffusion problem by combining Lagrangian techniques and theoretical modelling of the diffusion. Numerical simulations obtained with the DSM are in reasonable agreement with quantitative dye visualization experiments of the scalar fields. A theoretical model based on log-normal Probability Density Functions (PDFs) of stretching factors, characteristic of homogeneous turbulence in the Batchelor regime, allows to predict the PDFs of scalar in agreement with numerical and experimental results. This model also indicates that the PDFs of scalar are asymptotically close to log-normal at late stages, except for the large concentration levels which correspond to low stretching factors

  16. Decision process in MCDM with large number of criteria and heterogeneous risk preferences

    Directory of Open Access Journals (Sweden)

    Jian Liu

    Full Text Available A new decision process is proposed to address the challenge that a large number criteria in the multi-criteria decision making (MCDM problem and the decision makers with heterogeneous risk preferences. First, from the perspective of objective data, the effective criteria are extracted based on the similarity relations between criterion values and the criteria are weighted, respectively. Second, the corresponding types of theoretic model of risk preferences expectations will be built, based on the possibility and similarity between criterion values to solve the problem for different interval numbers with the same expectation. Then, the risk preferences (Risk-seeking, risk-neutral and risk-aversion will be embedded in the decision process. Later, the optimal decision object is selected according to the risk preferences of decision makers based on the corresponding theoretic model. Finally, a new algorithm of information aggregation model is proposed based on fairness maximization of decision results for the group decision, considering the coexistence of decision makers with heterogeneous risk preferences. The scientific rationality verification of this new method is given through the analysis of real case. Keywords: Heterogeneous, Risk preferences, Fairness, Decision process, Group decision

  17. New approaches to phylogenetic tree search and their application to large numbers of protein alignments.

    Science.gov (United States)

    Whelan, Simon

    2007-10-01

    Phylogenetic tree estimation plays a critical role in a wide variety of molecular studies, including molecular systematics, phylogenetics, and comparative genomics. Finding the optimal tree relating a set of sequences using score-based (optimality criterion) methods, such as maximum likelihood and maximum parsimony, may require all possible trees to be considered, which is not feasible even for modest numbers of sequences. In practice, trees are estimated using heuristics that represent a trade-off between topological accuracy and speed. I present a series of novel algorithms suitable for score-based phylogenetic tree reconstruction that demonstrably improve the accuracy of tree estimates while maintaining high computational speeds. The heuristics function by allowing the efficient exploration of large numbers of trees through novel hill-climbing and resampling strategies. These heuristics, and other computational approximations, are implemented for maximum likelihood estimation of trees in the program Leaphy, and its performance is compared to other popular phylogenetic programs. Trees are estimated from 4059 different protein alignments using a selection of phylogenetic programs and the likelihoods of the tree estimates are compared. Trees estimated using Leaphy are found to have equal to or better likelihoods than trees estimated using other phylogenetic programs in 4004 (98.6%) families and provide a unique best tree that no other program found in 1102 (27.1%) families. The improvement is particularly marked for larger families (80 to 100 sequences), where Leaphy finds a unique best tree in 81.7% of families.

  18. [Number of suicides in Spain: differences between data from the Spanish Statistical Office and the Institutes of Legal Medicine].

    Science.gov (United States)

    Giner, Lucas; Guija, Julio A

    2014-01-01

    To be able to prevent suicides, The exact magnitude of suicides must be known in order to prevent them. There is evidence that data provided on the number of suicides by the Spanish Statistical Office (Instituto Nacional de Estadística [INE]) differs from that identified by forensic pathologists. This paper aims to determine whether the INE data are to the same as those recorded by the agencies responsible for conducting autopsies in Spain (IML), and calculate the number of missing cases. IML were requested to provide the number of suicides in a five year period (2006-2010) and this was compared with those offered by INE in its site. A new rate of suicides per 100,000 was obtained and used to calculate the number of suicides in Spain. For every year of the studied period, the number of suicides reported by the INE was lower than that obtained directly from the IML. Using the highest annual suicide rate registered by province and the total, a count was obtained of identified suicides that for some reason had not been recorded in the INE or the IML data. Based on these figures, the mean rate of suicides per 100,000 was 0.97 (SD 0.10) higher than official INE data, which indicates a mean loss of 443.86 (SD 46.72) cases reported each year. Possible factors that may influence the missing recorded cases are discussed. According to the results, there is a discrepancy between INE and IML about the number of suicides in Spain. Neither of the two sources can be considered more reliable than the other. Copyright © 2013 SEP y SEPB. Published by Elsevier España. All rights reserved.

  19. Fluctuations of nuclear cross sections in the region of strong overlapping resonances and at large number of open channels

    International Nuclear Information System (INIS)

    Kun, S.Yu.

    1985-01-01

    On the basis of the symmetrized Simonius representation of the S matrix statistical properties of its fluctuating component in the presence of direct reactions are investigated. The case is considered where the resonance levels are strongly overlapping and there is a lot of open channels, assuming that compound-nucleus cross sections which couple different channels are equal. It is shown that using the averaged unitarity condition on the real energy axis one can eliminate both resonance-resonance and channel-channel correlations from partial r transition amplitudes. As a result, we derive the basic points of the Epicson fluctuation theory of nuclear cross sections, independently of the relation between the resonance overlapping and the number of open channels, and the validity of the Hauser-Feshbach model is established. If the number of open channels is large, the time of uniform population of compound-nucleus configurations, for an open excited nuclear system, is much smaller than the Poincare time. The life time of compound nucleus is discussed

  20. CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs

    Directory of Open Access Journals (Sweden)

    Djordjevic Marko

    2012-07-01

    Full Text Available Abstract Background CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated sequences is a recently discovered prokaryotic defense system against foreign DNA, including viruses and plasmids. CRISPR cassette is transcribed as a continuous transcript (pre-crRNA, which is processed by Cas proteins into small RNA molecules (crRNAs that are responsible for defense against invading viruses. Experiments in E. coli report that overexpression of cas genes generates a large number of crRNAs, from only few pre-crRNAs. Results We here develop a minimal model of CRISPR processing, which we parameterize based on available experimental data. From the model, we show that the system can generate a large amount of crRNAs, based on only a small decrease in the amount of pre-crRNAs. The relationship between the decrease of pre-crRNAs and the increase of crRNAs corresponds to strong linear amplification. Interestingly, this strong amplification crucially depends on fast non-specific degradation of pre-crRNA by an unidentified nuclease. We show that overexpression of cas genes above a certain level does not result in further increase of crRNA, but that this saturation can be relieved if the rate of CRISPR transcription is increased. We furthermore show that a small increase of CRISPR transcription rate can substantially decrease the extent of cas gene activation necessary to achieve a desired amount of crRNA. Conclusions The simple mathematical model developed here is able to explain existing experimental observations on CRISPR transcript processing in Escherichia coli. The model shows that a competition between specific pre-crRNA processing and non-specific degradation determines the steady-state levels of crRNA and is responsible for strong linear amplification of crRNAs when cas genes are overexpressed. The model further shows how disappearance of only a few pre-crRNA molecules normally present in the cell can lead to a large (two

  1. A Theory of Evolving Natural Constants Based on the Unification of General Theory of Relativity and Dirac's Large Number Hypothesis

    International Nuclear Information System (INIS)

    Peng Huanwu

    2005-01-01

    Taking Dirac's large number hypothesis as true, we have shown [Commun. Theor. Phys. (Beijing, China) 42 (2004) 703] the inconsistency of applying Einstein's theory of general relativity with fixed gravitation constant G to cosmology, and a modified theory for varying G is found, which reduces to Einstein's theory outside the gravitating body for phenomena of short duration in small distances, thereby agrees with all the crucial tests formerly supporting Einstein's theory. The modified theory, when applied to the usual homogeneous cosmological model, gives rise to a variable cosmological tensor term determined by the derivatives of G, in place of the cosmological constant term usually introduced ad hoc. Without any free parameter the theoretical Hubble's relation obtained from the modified theory seems not in contradiction to observations, as Dr. Wang's preliminary analysis of the recent data indicates [Commun. Theor. Phys. (Beijing, China) 42 (2004) 703]. As a complement to Commun. Theor. Phys. (Beijing, China) 42 (2004) 703 we shall study in this paper the modification of electromagnetism due to Dirac's large number hypothesis in more detail to show that the approximation of geometric optics still leads to null geodesics for the path of light, and that the general relation between the luminosity distance and the proper geometric distance is still valid in our theory as in Einstein's theory, and give the equations for homogeneous cosmological model involving matter plus electromagnetic radiation. Finally we consider the impact of the modification to quantum mechanics and statistical mechanics, and arrive at a systematic theory of evolving natural constants including Planck's h-bar as well as Boltzmann's k B by finding out their cosmologically combined counterparts with factors of appropriate powers of G that may remain truly constant to cosmologically long time.

  2. "Going to town": Large-scale norming and statistical analysis of 870 American English idioms.

    Science.gov (United States)

    Bulkes, Nyssa Z; Tanner, Darren

    2017-04-01

    An idiom is classically defined as a formulaic sequence whose meaning is comprised of more than the sum of its parts. For this reason, idioms pose a unique problem for models of sentence processing, as researchers must take into account how idioms vary and along what dimensions, as these factors can modulate the ease with which an idiomatic interpretation can be activated. In order to help ensure external validity and comparability across studies, idiom research benefits from the availability of publicly available resources reporting ratings from a large number of native speakers. Resources such as the one outlined in the current paper facilitate opportunities for consensus across studies on idiom processing and help to further our goals as a research community. To this end, descriptive norms were obtained for 870 American English idioms from 2,100 participants along five dimensions: familiarity, meaningfulness, literal plausibility, global decomposability, and predictability. Idiom familiarity and meaningfulness strongly correlated with one another, whereas familiarity and meaningfulness were positively correlated with both global decomposability and predictability. Correlations with previous norming studies are also discussed.

  3. Statistical analysis of uncertainties of gamma-peak identification and area calculation in particulate air-filter environment radionuclide measurements using the results of a Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) organized intercomparison, Part I: Assessment of reliability and uncertainties of isotope detection and energy precision using artificial spiked test spectra, Part II: Assessment of the true type I error rate and the quality of peak area estimators in relation to type II errors using large numbers of natural spectra

    International Nuclear Information System (INIS)

    Zhang, W.; Zaehringer, M.; Ungar, K.; Hoffman, I.

    2008-01-01

    In this paper, the uncertainties of gamma-ray small peak analysis have been examined. As the intensity of a gamma-ray peak approaches its detection decision limit, derived parameters such as centroid channel energy, peak area, peak area uncertainty, baseline determination, and peak significance are statistically sensitive. The intercomparison exercise organized by the CTBTO provided an excellent opportunity for this to be studied. Near background levels, the false-positive and false-negative peak identification frequencies in artificial test spectra have been compared to statistically predictable limiting values. In addition, naturally occurring radon progeny were used to compare observed variance against nominal uncertainties. The results infer that the applied fit algorithms do not always represent the best estimator. Understanding the statistically predicted peak-finding limit is important for data evaluation and analysis assessment. Furthermore, these results are useful to optimize analytical procedures to achieve the best results

  4. Space Situational Awareness of Large Numbers of Payloads From a Single Deployment

    Science.gov (United States)

    Segerman, A.; Byers, J.; Emmert, J.; Nicholas, A.

    2014-09-01

    The nearly simultaneous deployment of a large number of payloads from a single vehicle presents a new challenge for space object catalog maintenance and space situational awareness (SSA). Following two cubesat deployments last November, it took five weeks to catalog the resulting 64 orbits. The upcoming Kicksat mission will present an even greater SSA challenge, with its deployment of 128 chip-sized picosats. Although all of these deployments are in short-lived orbits, future deployments will inevitably occur at higher altitudes, with a longer term threat of collision with active spacecraft. With such deployments, individual scientific payload operators require rapid precise knowledge of their satellites' locations. Following the first November launch, the cataloguing did not initially associate a payload with each orbit, leaving this to the satellite operators. For short duration missions, the time required to identify an experiment's specific orbit may easily be a large fraction of the spacecraft's lifetime. For a Kicksat-type deployment, present tracking cannot collect enough observations to catalog each small object. The current approach is to treat the chip cloud as a single catalog object. However, the cloud dissipates into multiple subclouds and, ultimately, tiny groups of untrackable chips. One response to this challenge may be to mandate installation of a transponder on each spacecraft. Directional transponder transmission detections could be used as angle observations for orbit cataloguing. Of course, such an approach would only be employable with cooperative spacecraft. In other cases, a probabilistic association approach may be useful, with the goal being to establish the probability of an element being at a given point in space. This would permit more reliable assessment of the probability of collision of active spacecraft with any cloud element. This paper surveys the cataloguing challenges presented by large scale deployments of small spacecraft

  5. A method for express estimation of the octane number of gasoline using a portable spectroimpedance meter and statistical analysis methods

    Directory of Open Access Journals (Sweden)

    Mamykin A. V.

    2017-10-01

    Full Text Available The authors propose a method for determination of the electro-physical characteristics of electrical insulating liquids on the example of different types of gasoline. The method is based on the spectral impedance measurements of a capacitor electrochemical cell filled with the liquid under study. The application of sinusoidal test voltage in the frequency range of 0,1—10 Hz provides more accurate measurements in comparison with known traditional methods. A portable device for measuring total electrical resistance (impedance of dielectric liquids was designed and constructed. An approach for express estimation of octane number of automobile gasoline using spectroimpedance measurements and statistical multi variation methods of data analysis has been proposed and tested.

  6. TRAN-STAT: statistics for environmental studies, Number 22. Comparison of soil-sampling techniques for plutonium at Rocky Flats

    International Nuclear Information System (INIS)

    Gilbert, R.O.; Bernhardt, D.E.; Hahn, P.B.

    1983-01-01

    A summary of a field soil sampling study conducted around the Rocky Flats Colorado plant in May 1977 is preseted. Several different soil sampling techniques that had been used in the area were applied at four different sites. One objective was to comparethe average 239 - 240 Pu concentration values obtained by the various soil sampling techniques used. There was also interest in determining whether there are differences in the reproducibility of the various techniques and how the techniques compared with the proposed EPA technique of sampling to 1 cm depth. Statistically significant differences in average concentrations between the techniques were found. The differences could be largely related to the differences in sampling depth-the primary physical variable between the techniques. The reproducibility of the techniques was evaluated by comparing coefficients of variation. Differences between coefficients of variation were not statistically significant. Average (median) coefficients ranged from 21 to 42 percent for the five sampling techniques. A laboratory study indicated that various sample treatment and particle sizing techniques could increase the concentration of plutonium in the less than 10 micrometer size fraction by up to a factor of about 4 compared to the 2 mm size fraction

  7. [Statistical (Poisson) motor unit number estimation. Methodological aspects and normal results in the extensor digitorum brevis muscle of healthy subjects].

    Science.gov (United States)

    Murga Oporto, L; Menéndez-de León, C; Bauzano Poley, E; Núñez-Castaín, M J

    Among the differents techniques for motor unit number estimation (MUNE) there is the statistical one (Poisson), in which the activation of motor units is carried out by electrical stimulation and the estimation performed by means of a statistical analysis based on the Poisson s distribution. The study was undertaken in order to realize an approximation to the MUNE Poisson technique showing a coprehensible view of its methodology and also to obtain normal results in the extensor digitorum brevis muscle (EDB) from a healthy population. One hundred fourteen normal volunteers with age ranging from 10 to 88 years were studied using the MUNE software contained in a Viking IV system. The normal subjects were divided into two age groups (10 59 and 60 88 years). The EDB MUNE from all them was 184 49. Both, the MUNE and the amplitude of the compound muscle action potential (CMAP) were significantly lower in the older age group (page than CMAP amplitude ( 0.5002 and 0.4142, respectively pphisiology of the motor unit. The value of MUNE correlates better with the neuromuscular aging process than CMAP amplitude does.

  8. Droplet Breakup in Asymmetric T-Junctions at Intermediate to Large Capillary Numbers

    Science.gov (United States)

    Sadr, Reza; Cheng, Way Lee

    2017-11-01

    Splitting of a parent droplet into multiple daughter droplets of desired sizes is usually desired to enhance production and investigational efficiency in microfluidic devices. This can be done in an active or passive mode depending on whether an external power sources is used or not. In this study, three-dimensional simulations were done using the Volume-of-Fluid (VOF) method to analyze droplet splitting in asymmetric T-junctions with different outlet lengths. The parent droplet is divided into two uneven portions the volumetric ratio of the daughter droplets, in theory, depends on the length ratios of the outlet branches. The study identified various breakup modes such as primary, transition, bubble and non-breakup under various flow conditions and the configuration of the T-junctions. In addition, an analysis with the primary breakup regimes were conducted to study the breakup mechanisms. The results show that the way the droplet splits in an asymmetric T-junction is different than the process in a symmetric T-junction. A model for the asymmetric breakup criteria at intermediate or large Capillary number is presented. The proposed model is an expanded version to a theoretically derived model for the symmetric droplet breakup under similar flow conditions.

  9. Growth of equilibrium structures built from a large number of distinct component types.

    Science.gov (United States)

    Hedges, Lester O; Mannige, Ranjan V; Whitelam, Stephen

    2014-09-14

    We use simple analytic arguments and lattice-based computer simulations to study the growth of structures made from a large number of distinct component types. Components possess 'designed' interactions, chosen to stabilize an equilibrium target structure in which each component type has a defined spatial position, as well as 'undesigned' interactions that allow components to bind in a compositionally-disordered way. We find that high-fidelity growth of the equilibrium target structure can happen in the presence of substantial attractive undesigned interactions, as long as the energy scale of the set of designed interactions is chosen appropriately. This observation may help explain why equilibrium DNA 'brick' structures self-assemble even if undesigned interactions are not suppressed [Ke et al. Science, 338, 1177, (2012)]. We also find that high-fidelity growth of the target structure is most probable when designed interactions are drawn from a distribution that is as narrow as possible. We use this result to suggest how to choose complementary DNA sequences in order to maximize the fidelity of multicomponent self-assembly mediated by DNA. We also comment on the prospect of growing macroscopic structures in this manner.

  10. Source of vacuum electromagnetic zero-point energy and Dirac's large numbers hypothesis

    International Nuclear Information System (INIS)

    Simaciu, I.; Dumitrescu, G.

    1993-01-01

    The stochastic electrodynamics states that zero-point fluctuation of the vacuum (ZPF) is an electromagnetic zero-point radiation with spectral density ρ(ω)=ℎω 3 / 2π 2 C 3 . Protons, free electrons and atoms are sources for this radiation. Each of them absorbs and emits energy by interacting with ZPF. At equilibrium ZPF radiation is scattered by dipoles.Scattered radiation spectral density is ρ(ω,r) ρ(ω).c.σ(ω) / 4πr 2 . Radiation of dipole spectral density of Universe is ρ ∫ 0 R nρ(ω,r)4πr 2 dr. But if σ atom P e σ=σ T then ρ ρ(ω)σ T R.n. Moreover if ρ=ρ(ω) then σ T Rn = 1. With R = G M/c 2 and σ T ≅(e 2 /m e c 2 ) 2 ∝ r e 2 then σ T .Rn 1 is equivalent to R/r e = e 2 /Gm p m e i.e. the cosmological coincidence discussed in the context of Dirac's large-numbers hypothesis. (Author)

  11. On the chromatic number of triangle-free graphs of large minimum degree

    DEFF Research Database (Denmark)

    Thomassen, Carsten

    2002-01-01

    We prove that, for each. fixed real number c > 1/3, the triangle-free graphs of minimum degree at least cn (where n is the number of vertices) have bounded chromatic number. This problem was raised by Erdos and Simonovits in 1973 who pointed out that there is no such result for c <1/3.......We prove that, for each. fixed real number c > 1/3, the triangle-free graphs of minimum degree at least cn (where n is the number of vertices) have bounded chromatic number. This problem was raised by Erdos and Simonovits in 1973 who pointed out that there is no such result for c

  12. Development of the Large-Scale Statistical Analysis System of Satellites Observations Data with Grid Datafarm Architecture

    Science.gov (United States)

    Yamamoto, K.; Murata, K.; Kimura, E.; Honda, R.

    2006-12-01

    number of files and the elapsed time, parallel and distributed processing shorten the elapsed time to 1/5 than sequential processing. On the other hand, sequential processing times were shortened in another experiment, whose file size is smaller than 100KB. In this case, the elapsed time to scan one file is within one second. It implies that disk swap took place in case of parallel processing by each node. We note that the operation became unstable when the number of the files exceeded 1000. To overcome the problem (iii), we developed an original data class. This class supports our reading of data files with various data formats since it converts them into an original data format since it defines schemata for every type of data and encapsulates the structure of data files. In addition, since this class provides a function of time re-sampling, users can easily convert multiple data (array) with different time resolution into the same time resolution array. Finally, using the Gfarm, we achieved a high performance environment for large-scale statistical data analyses. It should be noted that the present method is effective only when one data file size is large enough. At present, we are restructuring the new Gfarm environment with 8 nodes: CPU is Athlon 64 x2 Dual Core 2GHz, 2GB memory and 1.2TB disk (using RAID0) for each node. Our original class is to be implemented on the new Gfarm environment. In the present talk, we show the latest results with applying the present system for data analyses with huge number of satellite observation data files.

  13. A Statistical Test for Identifying the Number of Creep Regimes When Using the Wilshire Equations for Creep Property Predictions

    Science.gov (United States)

    Evans, Mark

    2016-12-01

    A new parametric approach, termed the Wilshire equations, offers the realistic potential of being able to accurately lift materials operating at in-service conditions from accelerated test results lasting no more than 5000 hours. The success of this approach can be attributed to a well-defined linear relationship that appears to exist between various creep properties and a log transformation of the normalized stress. However, these linear trends are subject to discontinuities, the number of which appears to differ from material to material. These discontinuities have until now been (1) treated as abrupt in nature and (2) identified by eye from an inspection of simple graphical plots of the data. This article puts forward a statistical test for determining the correct number of discontinuities present within a creep data set and a method for allowing these discontinuities to occur more gradually, so that the methodology is more in line with the accepted view as to how creep mechanisms evolve with changing test conditions. These two developments are fully illustrated using creep data sets on two steel alloys. When these new procedures are applied to these steel alloys, not only do they produce more accurate and realistic looking long-term predictions of the minimum creep rate, but they also lead to different conclusions about the mechanisms determining the rates of creep from those originally put forward by Wilshire.

  14. Statistical fluctuations of the number of neutrons in a pile; Fluctuations statistiques du nombre de neutrons dans une pile

    Energy Technology Data Exchange (ETDEWEB)

    Raievski, V [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The theory of the statistical fluctuations in a pile is extended to the space dependent case, and gives the fluctuations of the number of neutrons in a cell of the core or reflector of the pile. This number changes through elementary processes occurring at random, which are, capture, source, fission and scattering. Of all these processes, fission is the only one which changes more than one neutron at a time and so is responsible of the deviation of the fluctuations from a Poisson law. The importance of this deviation depends on the dimensions of the cell compared to the slowing down length. When the dimensions are small, the fluctuations close to a Poisson law. (author) [French] La theorie des fluctuations statistiques est etendue au cas local et donne les fluctuations du nombre de neutrons dans une cellule situee dans le coeur ou le reflecteur de la pile. Ce nombre evolue au cours du temps sous l'influence de phenomenes aleatoires qui sont la capture, la diffusion, les sources et les neutrons secondaires de fission. L'emission simultanee de plusieurs neutrons distingue ce phenomene des precedents qui n'affectent qu'un neutron individuellement. L'importance de ce phenomene sur la loi de fluctuation depend des dimensions de la cellule par rapport a la longueur de ralentissement. Quand ces dimensions sont petites, le caractere particulier de ce phenomene disparait. (auteur)

  15. On the chromatic number of pentagon-free graphs of large minimum degree

    DEFF Research Database (Denmark)

    Thomassen, Carsten

    2007-01-01

    We prove that, for each fixed real number c > 0, the pentagon-free graphs of minimum degree at least cn (where n is the number of vertices) have bounded chromatic number. This problem was raised by Erdős and Simonovits in 1973. A similar result holds for any other fixed odd cycle, except the tria...

  16. Tree-space statistics and approximations for large-scale analysis of anatomical trees

    DEFF Research Database (Denmark)

    Feragen, Aasa; Owen, Megan; Petersen, Jens

    2013-01-01

    parametrize the relevant parts of tree-space well. Using the developed approximate statistics, we illustrate how the structure and geometry of airway trees vary across a population and show that airway trees with Chronic Obstructive Pulmonary Disease come from a different distribution in tree-space than...

  17. Understanding Statistics - Cancer Statistics

    Science.gov (United States)

    Annual reports of U.S. cancer statistics including new cases, deaths, trends, survival, prevalence, lifetime risk, and progress toward Healthy People targets, plus statistical summaries for a number of common cancer types.

  18. On the Behavior of ECN/RED Gateways Under a Large Number of TCP Flows: Limit Theorems

    National Research Council Canada - National Science Library

    Tinnakornsrisuphap, Peerapol; Makowski, Armand M

    2005-01-01

    .... As the number of competing flows becomes large, the asymptotic queue behavior at the gateway can be described by a simple recursion and the throughput behavior of individual TCP flows becomes asymptotically independent...

  19. On the Transfer of a Number of Concepts of Statistical Radiophysics to the Theory of One-dimensional Point Mappings

    Directory of Open Access Journals (Sweden)

    Agalar M. Agalarov

    2018-01-01

    Full Text Available In the article, the possibility of using a bispectrum under the investigation of regular and chaotic behaviour of one-dimensional point mappings is discussed. The effectiveness of the transfer of this concept to nonlinear dynamics was demonstrated by an example of the Feigenbaum mapping. Also in the work, the application of the Kullback-Leibler entropy in the theory of point mappings is considered. It has been shown that this information-like value is able to describe the behaviour of statistical ensembles of one-dimensional mappings. In the framework of this theory some general properties of its behaviour were found out. Constructivity of the Kullback-Leibler entropy in the theory of point mappings was shown by means of its direct calculation for the ”saw tooth” mapping with linear initial probability density. Moreover, for this mapping the denumerable set of initial probability densities hitting into its stationary probability density after a finite number of steps was pointed out. 

  20. Numerical analysis of jet impingement heat transfer at high jet Reynolds number and large temperature difference

    DEFF Research Database (Denmark)

    Jensen, Michael Vincent; Walther, Jens Honore

    2013-01-01

    was investigated at a jet Reynolds number of 1.66 × 105 and a temperature difference between jet inlet and wall of 1600 K. The focus was on the convective heat transfer contribution as thermal radiation was not included in the investigation. A considerable influence of the turbulence intensity at the jet inlet...... to about 100% were observed. Furthermore, the variation in stagnation point heat transfer was examined for jet Reynolds numbers in the range from 1.10 × 105 to 6.64 × 105. Based on the investigations, a correlation is suggested between the stagnation point Nusselt number, the jet Reynolds number......, and the turbulence intensity at the jet inlet for impinging jet flows at high jet Reynolds numbers. Copyright © 2013 Taylor and Francis Group, LLC....

  1. Multiparametric statistics

    CERN Document Server

    Serdobolskii, Vadim Ivanovich

    2007-01-01

    This monograph presents mathematical theory of statistical models described by the essentially large number of unknown parameters, comparable with sample size but can also be much larger. In this meaning, the proposed theory can be called "essentially multiparametric". It is developed on the basis of the Kolmogorov asymptotic approach in which sample size increases along with the number of unknown parameters.This theory opens a way for solution of central problems of multivariate statistics, which up until now have not been solved. Traditional statistical methods based on the idea of an infinite sampling often break down in the solution of real problems, and, dependent on data, can be inefficient, unstable and even not applicable. In this situation, practical statisticians are forced to use various heuristic methods in the hope the will find a satisfactory solution.Mathematical theory developed in this book presents a regular technique for implementing new, more efficient versions of statistical procedures. ...

  2. Arbitrarily large numbers of kink internal modes in inhomogeneous sine-Gordon equations

    Energy Technology Data Exchange (ETDEWEB)

    González, J.A., E-mail: jalbertgonz@yahoo.es [Department of Physics, Florida International University, Miami, FL 33199 (United States); Department of Natural Sciences, Miami Dade College, 627 SW 27th Ave., Miami, FL 33135 (United States); Bellorín, A., E-mail: alberto.bellorin@ucv.ve [Escuela de Física, Facultad de Ciencias, Universidad Central de Venezuela, Apartado Postal 47586, Caracas 1041-A (Venezuela, Bolivarian Republic of); García-Ñustes, M.A., E-mail: monica.garcia@pucv.cl [Instituto de Física, Pontificia Universidad Católica de Valparaíso, Casilla 4059 (Chile); Guerrero, L.E., E-mail: lguerre@usb.ve [Departamento de Física, Universidad Simón Bolívar, Apartado Postal 89000, Caracas 1080-A (Venezuela, Bolivarian Republic of); Jiménez, S., E-mail: s.jimenez@upm.es [Departamento de Matemática Aplicada a las TT.II., E.T.S.I. Telecomunicación, Universidad Politécnica de Madrid, 28040-Madrid (Spain); Vázquez, L., E-mail: lvazquez@fdi.ucm.es [Departamento de Matemática Aplicada, Facultad de Informática, Universidad Complutense de Madrid, 28040-Madrid (Spain)

    2017-06-28

    We prove analytically the existence of an infinite number of internal (shape) modes of sine-Gordon solitons in the presence of some inhomogeneous long-range forces, provided some conditions are satisfied. - Highlights: • We have found exact kink solutions to the perturbed sine-Gordon equation. • We have been able to study analytically the kink stability problem. • A kink equilibrated by an exponentially-localized perturbation has a finite number of oscillation modes. • A sufficiently broad equilibrating perturbation supports an infinite number of soliton internal modes.

  3. Statistics on gene-based laser speckles with a small number of scatterers: implications for the detection of polymorphism in the Chlamydia trachomatis omp1 gene

    Science.gov (United States)

    Ulyanov, Sergey S.; Ulianova, Onega V.; Zaytsev, Sergey S.; Saltykov, Yury V.; Feodorova, Valentina A.

    2018-04-01

    The transformation mechanism for a nucleotide sequence of the Chlamydia trachomatis gene into a speckle pattern has been considered. The first and second-order statistics of gene-based speckles have been analyzed. It has been demonstrated that gene-based speckles do not obey Gaussian statistics and belong to the class of speckles with a small number of scatterers. It has been shown that gene polymorphism can be easily detected through analysis of the statistical characteristics of gene-based speckles.

  4. The estimation of differential counting measurements of possitive quantities with relatively large statistical errors

    International Nuclear Information System (INIS)

    Vincent, C.H.

    1982-01-01

    Bayes' principle is applied to the differential counting measurement of a positive quantity in which the statistical errors are not necessarily small in relation to the true value of the quantity. The methods of estimation derived are found to give consistent results and to avoid the anomalous negative estimates sometimes obtained by conventional methods. One of the methods given provides a simple means of deriving the required estimates from conventionally presented results and appears to have wide potential applications. Both methods provide the actual posterior probability distribution of the quantity to be measured. A particularly important potential application is the correction of counts on low radioacitvity samples for background. (orig.)

  5. A Statistical Modeling Framework for Characterising Uncertainty in Large Datasets: Application to Ocean Colour

    Directory of Open Access Journals (Sweden)

    Peter E. Land

    2018-05-01

    Full Text Available Uncertainty estimation is crucial to establishing confidence in any data analysis, and this is especially true for Essential Climate Variables, including ocean colour. Methods for deriving uncertainty vary greatly across data types, so a generic statistics-based approach applicable to multiple data types is an advantage to simplify the use and understanding of uncertainty data. Progress towards rigorous uncertainty analysis of ocean colour has been slow, in part because of the complexity of ocean colour processing. Here, we present a general approach to uncertainty characterisation, using a database of satellite-in situ matchups to generate a statistical model of satellite uncertainty as a function of its contributing variables. With an example NASA MODIS-Aqua chlorophyll-a matchups database mostly covering the north Atlantic, we demonstrate a model that explains 67% of the squared error in log(chlorophyll-a as a potentially correctable bias, with the remaining uncertainty being characterised as standard deviation and standard error at each pixel. The method is quite general, depending only on the existence of a suitable database of matchups or reference values, and can be applied to other sensors and data types such as other satellite observed Essential Climate Variables, empirical algorithms derived from in situ data, or even model data.

  6. Use of a statistical model of the whole femur in a large scale, multi-model study of femoral neck fracture risk.

    Science.gov (United States)

    Bryan, Rebecca; Nair, Prasanth B; Taylor, Mark

    2009-09-18

    Interpatient variability is often overlooked in orthopaedic computational studies due to the substantial challenges involved in sourcing and generating large numbers of bone models. A statistical model of the whole femur incorporating both geometric and material property variation was developed as a potential solution to this problem. The statistical model was constructed using principal component analysis, applied to 21 individual computer tomography scans. To test the ability of the statistical model to generate realistic, unique, finite element (FE) femur models it was used as a source of 1000 femurs to drive a study on femoral neck fracture risk. The study simulated the impact of an oblique fall to the side, a scenario known to account for a large proportion of hip fractures in the elderly and have a lower fracture load than alternative loading approaches. FE model generation, application of subject specific loading and boundary conditions, FE processing and post processing of the solutions were completed automatically. The generated models were within the bounds of the training data used to create the statistical model with a high mesh quality, able to be used directly by the FE solver without remeshing. The results indicated that 28 of the 1000 femurs were at highest risk of fracture. Closer analysis revealed the percentage of cortical bone in the proximal femur to be a crucial differentiator between the failed and non-failed groups. The likely fracture location was indicated to be intertrochantic. Comparison to previous computational, clinical and experimental work revealed support for these findings.

  7. Statistical characteristics and stability index (si) of large-sized landslide dams around the world

    International Nuclear Information System (INIS)

    Iqbal, J.; Dai, F.; Raja, I.A.

    2014-01-01

    In the last few decades, landslide dams have received greater attention of researchers, as they have caused loss to property and human lives. Over 261 large-sized landslide dams from different countries of the world with volume greater than 1 x 105 m have been reviewed for this study. The data collected for this study shows that 58% of the catastrophic landslides were triggered by earthquakes and 21 % by rainfall, revealing that earthquake and rainfall are the two major triggers, accounting for 75% of large-sized landslide dams. These land-slides were most frequent during last two decades (1990-2010) throughout the world. The mean landslide dam volume of the studied cases was 53.39 x 10 m with mean dam height of 71.98 m, while the mean lake volume was found to be 156.62 x 10 m. Failure of these large landslide dams pose a severe threat to the property and people living downstream, hence immediate attention is required to deal with this problem. A stability index (SI) has been derived on the basis on 59 large-sized landslide dams (out of the 261 dams) with complete parametric information. (author)

  8. Combining large model ensembles with extreme value statistics to improve attribution statements of rare events

    Directory of Open Access Journals (Sweden)

    Sebastian Sippel

    2015-09-01

    In conclusion, our study shows that EVT and empirical estimates based on numerical simulations can indeed be used to productively inform each other, for instance to derive appropriate EVT parameters for short observational time series. Further, the combination of ensemble simulations with EVT allows us to significantly reduce the number of simulations needed for statements about the tails.

  9. Clinical Trials With Large Numbers of Variables: Important Advantages of Canonical Analysis.

    Science.gov (United States)

    Cleophas, Ton J

    2016-01-01

    Canonical analysis assesses the combined effects of a set of predictor variables on a set of outcome variables, but it is little used in clinical trials despite the omnipresence of multiple variables. The aim of this study was to assess the performance of canonical analysis as compared with traditional multivariate methods using multivariate analysis of covariance (MANCOVA). As an example, a simulated data file with 12 gene expression levels and 4 drug efficacy scores was used. The correlation coefficient between the 12 predictor and 4 outcome variables was 0.87 (P = 0.0001) meaning that 76% of the variability in the outcome variables was explained by the 12 covariates. Repeated testing after the removal of 5 unimportant predictor and 1 outcome variable produced virtually the same overall result. The MANCOVA identified identical unimportant variables, but it was unable to provide overall statistics. (1) Canonical analysis is remarkable, because it can handle many more variables than traditional multivariate methods such as MANCOVA can. (2) At the same time, it accounts for the relative importance of the separate variables, their interactions and differences in units. (3) Canonical analysis provides overall statistics of the effects of sets of variables, whereas traditional multivariate methods only provide the statistics of the separate variables. (4) Unlike other methods for combining the effects of multiple variables such as factor analysis/partial least squares, canonical analysis is scientifically entirely rigorous. (5) Limitations include that it is less flexible than factor analysis/partial least squares, because only 2 sets of variables are used and because multiple solutions instead of one is offered. We do hope that this article will stimulate clinical investigators to start using this remarkable method.

  10. Predictability of the recent slowdown and subsequent recovery of large-scale surface warming using statistical methods

    Science.gov (United States)

    Mann, Michael E.; Steinman, Byron A.; Miller, Sonya K.; Frankcombe, Leela M.; England, Matthew H.; Cheung, Anson H.

    2016-04-01

    The temporary slowdown in large-scale surface warming during the early 2000s has been attributed to both external and internal sources of climate variability. Using semiempirical estimates of the internal low-frequency variability component in Northern Hemisphere, Atlantic, and Pacific surface temperatures in concert with statistical hindcast experiments, we investigate whether the slowdown and its recent recovery were predictable. We conclude that the internal variability of the North Pacific, which played a critical role in the slowdown, does not appear to have been predictable using statistical forecast methods. An additional minor contribution from the North Atlantic, by contrast, appears to exhibit some predictability. While our analyses focus on combining semiempirical estimates of internal climatic variability with statistical hindcast experiments, possible implications for initialized model predictions are also discussed.

  11. Large Eddy Simulation of an SD7003 Airfoil: Effects of Reynolds number and Subgrid-scale modeling

    DEFF Research Database (Denmark)

    Sarlak Chivaee, Hamid

    2017-01-01

    This paper presents results of a series of numerical simulations in order to study aerodynamic characteristics of the low Reynolds number Selig-Donovan airfoil, SD7003. Large Eddy Simulation (LES) technique is used for all computations at chord-based Reynolds numbers 10,000, 24,000 and 60...... the Reynolds number, and the effect is visible even at a relatively low chord-Reynolds number of 60,000. Among the tested models, the dynamic Smagorinsky gives the poorest predictions of the flow, with overprediction of lift and a larger separation on airfoils suction side. Among various models, the implicit...

  12. Tail-constraining stochastic linear–quadratic control: a large deviation and statistical physics approach

    International Nuclear Information System (INIS)

    Chertkov, Michael; Kolokolov, Igor; Lebedev, Vladimir

    2012-01-01

    The standard definition of the stochastic risk-sensitive linear–quadratic (RS-LQ) control depends on the risk parameter, which is normally left to be set exogenously. We reconsider the classical approach and suggest two alternatives, resolving the spurious freedom naturally. One approach consists in seeking for the minimum of the tail of the probability distribution function (PDF) of the cost functional at some large fixed value. Another option suggests minimizing the expectation value of the cost functional under a constraint on the value of the PDF tail. Under the assumption of resulting control stability, both problems are reduced to static optimizations over a stationary control matrix. The solutions are illustrated using the examples of scalar and 1D chain (string) systems. The large deviation self-similar asymptotic of the cost functional PDF is analyzed. (paper)

  13. Sampling design in large-scale vegetation studies: Do not sacrifice ecological thinking to statistical purism!

    Czech Academy of Sciences Publication Activity Database

    Roleček, J.; Chytrý, M.; Hájek, Michal; Lvončík, S.; Tichý, L.

    2007-01-01

    Roč. 42, - (2007), s. 199-208 ISSN 1211-9520 R&D Projects: GA AV ČR IAA6163303; GA ČR(CZ) GA206/05/0020 Grant - others:GA AV ČR(CZ) KJB601630504 Institutional research plan: CEZ:AV0Z60050516 Keywords : Ecological methodology * Large-scale vegetation patterns * Macroecology Subject RIV: EF - Botanics Impact factor: 1.133, year: 2007

  14. A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan

    Directory of Open Access Journals (Sweden)

    Wu Jer-Yuarn

    2008-12-01

    Full Text Available Abstract Background Copy number variations (CNVs have recently been recognized as important structural variations in the human genome. CNVs can affect gene expression and thus may contribute to phenotypic differences. The copy number inferring tool (CNIT is an effective hidden Markov model-based algorithm for estimating allele-specific copy number and predicting chromosomal alterations from single nucleotide polymorphism microarrays. The CNIT algorithm, which was constructed using data from 270 HapMap multi-ethnic individuals, was applied to identify CNVs from 300 unrelated Han Chinese individuals in Taiwan. Results Using stringent selection criteria, 230 regions with variable copy numbers were identified in the Han Chinese population; 133 (57.83% had been reported previously, 64 displayed greater than 1% CNV allele frequency. The average size of the CNV regions was 322 kb (ranging from 1.48 kb to 5.68 Mb and covered a total of 2.47% of the human genome. A total of 196 of the CNV regions were simple deletions and 27 were simple amplifications. There were 449 genes and 5 microRNAs within these CNV regions; some of these genes are known to be associated with diseases. Conclusion The identified CNVs are characteristic of the Han Chinese population and should be considered when genetic studies are conducted. The CNV distribution in the human genome is still poorly characterized, and there is much diversity among different ethnic populations.

  15. Statistical analysis of error rate of large-scale single flux quantum logic circuit by considering fluctuation of timing parameters

    International Nuclear Information System (INIS)

    Yamanashi, Yuki; Masubuchi, Kota; Yoshikawa, Nobuyuki

    2016-01-01

    The relationship between the timing margin and the error rate of the large-scale single flux quantum logic circuits is quantitatively investigated to establish a timing design guideline. We observed that the fluctuation in the set-up/hold time of single flux quantum logic gates caused by thermal noises is the most probable origin of the logical error of the large-scale single flux quantum circuit. The appropriate timing margin for stable operation of the large-scale logic circuit is discussed by taking the fluctuation of setup/hold time and the timing jitter in the single flux quantum circuits. As a case study, the dependence of the error rate of the 1-million-bit single flux quantum shift register on the timing margin is statistically analyzed. The result indicates that adjustment of timing margin and the bias voltage is important for stable operation of a large-scale SFQ logic circuit.

  16. Statistical analysis of error rate of large-scale single flux quantum logic circuit by considering fluctuation of timing parameters

    Energy Technology Data Exchange (ETDEWEB)

    Yamanashi, Yuki, E-mail: yamanasi@ynu.ac.jp [Department of Electrical and Computer Engineering, Yokohama National University, Tokiwadai 79-5, Hodogaya-ku, Yokohama 240-8501 (Japan); Masubuchi, Kota; Yoshikawa, Nobuyuki [Department of Electrical and Computer Engineering, Yokohama National University, Tokiwadai 79-5, Hodogaya-ku, Yokohama 240-8501 (Japan)

    2016-11-15

    The relationship between the timing margin and the error rate of the large-scale single flux quantum logic circuits is quantitatively investigated to establish a timing design guideline. We observed that the fluctuation in the set-up/hold time of single flux quantum logic gates caused by thermal noises is the most probable origin of the logical error of the large-scale single flux quantum circuit. The appropriate timing margin for stable operation of the large-scale logic circuit is discussed by taking the fluctuation of setup/hold time and the timing jitter in the single flux quantum circuits. As a case study, the dependence of the error rate of the 1-million-bit single flux quantum shift register on the timing margin is statistically analyzed. The result indicates that adjustment of timing margin and the bias voltage is important for stable operation of a large-scale SFQ logic circuit.

  17. ENTROPY PRODUCTION IN COLLISIONLESS SYSTEMS. I. LARGE PHASE-SPACE OCCUPATION NUMBERS

    International Nuclear Information System (INIS)

    Barnes, Eric I.; Williams, Liliya L. R.

    2011-01-01

    Certain thermal non-equilibrium situations, outside of the astrophysical realm, suggest that entropy production extrema, instead of entropy extrema, are related to stationary states. In an effort to better understand the evolution of collisionless self-gravitating systems, we investigate the role of entropy production and develop expressions for the entropy production rate in two particular statistical families that describe self-gravitating systems. From these entropy production descriptions, we derive the requirements for extremizing the entropy production rate in terms of specific forms for the relaxation function in the Boltzmann equation. We discuss some implications of these relaxation functions and point to future work that will further test this novel thermodynamic viewpoint of collisionless relaxation.

  18. A Statistical Model for Hourly Large-Scale Wind and Photovoltaic Generation in New Locations

    DEFF Research Database (Denmark)

    Ekstrom, Jussi; Koivisto, Matti Juhani; Mellin, Ilkka

    2017-01-01

    The analysis of large-scale wind and photovoltaic (PV) energy generation is of vital importance in power systems where their penetration is high. This paper presents a modular methodology to assess the power generation and volatility of a system consisting of both PV plants (PVPs) and wind power...... of new PVPs and WPPs in system planning. The model is verified against hourly measured wind speed and solar irradiance data from Finland. A case study assessing the impact of the geographical distribution of the PVPs and WPPs on aggregate power generation and its variability is presented....

  19. Q-factorial Gorenstein toric Fano varieties with large Picard number

    DEFF Research Database (Denmark)

    Nill, Benjamin; Øbro, Mikkel

    2010-01-01

    In dimension $d$, ${\\boldsymbol Q}$-factorial Gorenstein toric Fano varieties with Picard number $\\rho_X$ correspond to simplicial reflexive polytopes with $\\rho_X + d$ vertices. Casagrande showed that any $d$-dimensional simplicial reflexive polytope has at most $3 d$ and $3d-1$ vertices if $d......$ is even and odd, respectively. Moreover, for $d$ even there is up to unimodular equivalence only one such polytope with $3 d$ vertices, corresponding to the product of $d/2$ copies of a del Pezzo surface of degree six. In this paper we completely classify all $d$-dimensional simplicial reflexive polytopes...... having $3d-1$ vertices, corresponding to $d$-dimensional ${\\boldsymbol Q}$-factorial Gorenstein toric Fano varieties with Picard number $2d-1$. For $d$ even, there exist three such varieties, with two being singular, while for $d > 1$ odd there exist precisely two, both being nonsingular toric fiber...

  20. A comment on "bats killed in large numbers at United States wind energy facilities"

    Science.gov (United States)

    Huso, Manuela M.P.; Dalthorp, Dan

    2014-01-01

    Widespread reports of bat fatalities caused by wind turbines have raised concerns about the impacts of wind power development. Reliable estimates of the total number killed and the potential effects on populations are needed, but it is crucial that they be based on sound data. In a recent BioScience article, Hayes (2013) estimated that over 600,000 bats were killed at wind turbines in the United States in 2012. The scientific errors in the analysis are numerous, with the two most serious being that the included sites constituted a convenience sample, not a representative sample, and that the individual site estimates are derived from such different methodologies that they are inherently not comparable. This estimate is almost certainly inaccurate, but whether the actual number is much smaller, much larger, or about the same is uncertain. An accurate estimate of total bat fatality is not currently possible, given the shortcomings of the available data.

  1. Efficient high speed communications over electrical powerlines for a large number of users

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J.; Tripathi, K.; Latchman, H.A. [Florida Univ., Gainesville, FL (United States). Dept. of Electrical and Computer Engineering

    2007-07-01

    Affordable broadband Internet communication is currently available for residential use via cable modem and other forms of digital subscriber lines (DSL). Powerline communication (PLC) systems were never considered seriously for communications due to their low speed and high development cost. However, due to technological advances PLCs are now spreading to local area networks and broadband over power line systems. This paper presented a newly proposed modification to the standard HomePlug 1.0 MAC protocol to make it a constant contention window-based scheme. The HomePlug 1.0 was developed based on orthogonal frequency division multiplexing (OFDM) and carrier sense multiple access with collision avoidance (CSMA/CA). It is currently the most commonly used technology of power line communications, supporting a transmission rate of up to 14 Mbps on the power line. However, the throughput performance of this original scheme becomes critical when the number of users increases. For that reason, a constant contention window based medium access control protocol algorithm of HomePlug 1.0 was proposed under the assumption that the number of active stations is known. An analytical framework based on Markov Chains was developed in order to model this modified protocol under saturation conditions. Modeling results accurately matched the actual performance of the system. This paper revealed that the performance can be improved significantly if the variables were parameterized in terms of the number of active stations. 15 refs., 1 tab., 6 figs.

  2. Evaluating statistical approaches to leverage large clinical datasets for uncovering therapeutic and adverse medication effects.

    Science.gov (United States)

    Choi, Leena; Carroll, Robert J; Beck, Cole; Mosley, Jonathan D; Roden, Dan M; Denny, Joshua C; Van Driest, Sara L

    2018-04-18

    Phenome-wide association studies (PheWAS) have been used to discover many genotype-phenotype relationships and have the potential to identify therapeutic and adverse drug outcomes using longitudinal data within electronic health records (EHRs). However, the statistical methods for PheWAS applied to longitudinal EHR medication data have not been established. In this study, we developed methods to address two challenges faced with reuse of EHR for this purpose: confounding by indication, and low exposure and event rates. We used Monte Carlo simulation to assess propensity score (PS) methods, focusing on two of the most commonly used methods, PS matching and PS adjustment, to address confounding by indication. We also compared two logistic regression approaches (the default of Wald vs. Firth's penalized maximum likelihood, PML) to address complete separation due to sparse data with low exposure and event rates. PS adjustment resulted in greater power than propensity score matching, while controlling Type I error at 0.05. The PML method provided reasonable p-values, even in cases with complete separation, with well controlled Type I error rates. Using PS adjustment and the PML method, we identify novel latent drug effects in pediatric patients exposed to two common antibiotic drugs, ampicillin and gentamicin. R packages PheWAS and EHR are available at https://github.com/PheWAS/PheWAS and at CRAN (https://www.r-project.org/), respectively. The R script for data processing and the main analysis is available at https://github.com/choileena/EHR. leena.choi@vanderbilt.edu. Supplementary data are available at Bioinformatics online.

  3. Statistical properties of edge plasma turbulence in the Large Helical Device

    Science.gov (United States)

    Dewhurst, J. M.; Hnat, B.; Ohno, N.; Dendy, R. O.; Masuzaki, S.; Morisaki, T.; Komori, A.

    2008-09-01

    Ion saturation current (Isat) measurements made by three tips of a Langmuir probe array in the Large Helical Device are analysed for two plasma discharges. Absolute moment analysis is used to quantify properties on different temporal scales of the measured signals, which are bursty and intermittent. Strong coherent modes in some datasets are found to distort this analysis and are consequently removed from the time series by applying bandstop filters. Absolute moment analysis of the filtered data reveals two regions of power-law scaling, with the temporal scale τ ≈ 40 µs separating the two regimes. A comparison is made with similar results from the Mega-Amp Spherical Tokamak. The probability density function is studied and a monotonic relationship between connection length and skewness is found. Conditional averaging is used to characterize the average temporal shape of the largest intermittent bursts.

  4. Detailed Measurements of Rayleigh-Taylor Mixing at Large and Small Atwood Numbers

    International Nuclear Information System (INIS)

    Malcolm, J.; Andrews, Ph.D.

    2004-01-01

    This project has two major tasks: Task 1. The construction of a new air/helium facility to collect detailed measurements of Rayleigh-Taylor (RT) mixing at high Atwood number, and the distribution of these data to LLNL, LANL, and Alliance members for code validation and design purposes. Task 2. The collection of initial condition data from the new Air/Helium facility, for use with validation of RT simulation codes at LLNL and LANL. Also, studies of multi-layer mixing with the existing water channel facility. Over the last twelve (12) months there has been excellent progress, detailed in this report, with both tasks. As of December 10, 2004, the air/helium facility is now complete and extensive testing and validation of diagnostics has been performed. Currently experiments with air/helium up to Atwood numbers of 0.25 (the maximum is 0.75, but the highest Reynolds numbers are at 0.25) are being performed. The progress matches the project plan, as does the budget, and we expect this to continue for 2005. With interest expressed from LLNL we have continued with initial condition studies using the water channel. This work has also progressed well, with one of the graduate Research Assistants (Mr. Nick Mueschke) visiting LLNL the past two summers to work with Dr. O. Schilling. Several journal papers are in preparation that describe the work. Two MSc.'s have been completed (Mr. Nick Mueschke, and Mr. Wayne Kraft, 12/1/03). Nick and Wayne are both pursuing Ph.D.s' funded by this DOE Alliances project. Presently three (3) Ph.D. graduate Research Assistants are supported on the project, and two (2) undergraduate Research Assistants. During the year two (2) journal papers and two (2) conference papers have been published, ten (10) presentations made at conferences, and three (3) invited presentations

  5. Mapping Ad Hoc Communications Network of a Large Number Fixed-Wing UAV Swarm

    Science.gov (United States)

    2017-03-01

    shows like "Agents of S.H.I.E.L.D". Inspiration can come from the imaginative minds of people or from the world around us. Swarms have demonstrated a...high degree of success. Bees , ants, termites, and naked mole rats maintain large groups that distribute tasks among individuals in order to achieve...the application layer and not the transport layer. Real- world vehicle-to-vehicle packet delivery rates for the 50-UAV swarm event were de- scribed in

  6. Linear optics and projective measurements alone suffice to create large-photon-number path entanglement

    International Nuclear Information System (INIS)

    Lee, Hwang; Kok, Pieter; Dowling, Jonathan P.; Cerf, Nicolas J.

    2002-01-01

    We propose a method for preparing maximal path entanglement with a definite photon-number N, larger than two, using projective measurements. In contrast with the previously known schemes, our method uses only linear optics. Specifically, we exhibit a way of generating four-photon, path-entangled states of the form vertical bar 4,0>+ vertical bar 0,4>, using only four beam splitters and two detectors. These states are of major interest as a resource for quantum interferometric sensors as well as for optical quantum lithography and quantum holography

  7. Laboratory Study of Magnetorotational Instability and Hydrodynamic Stability at Large Reynolds Numbers

    Science.gov (United States)

    Ji, H.; Burin, M.; Schartman, E.; Goodman, J.; Liu, W.

    2006-01-01

    Two plausible mechanisms have been proposed to explain rapid angular momentum transport during accretion processes in astrophysical disks: nonlinear hydrodynamic instabilities and magnetorotational instability (MRI). A laboratory experiment in a short Taylor-Couette flow geometry has been constructed in Princeton to study both mechanisms, with novel features for better controls of the boundary-driven secondary flows (Ekman circulation). Initial results on hydrodynamic stability have shown negligible angular momentum transport in Keplerian-like flows with Reynolds numbers approaching one million, casting strong doubt on the viability of nonlinear hydrodynamic instability as a source for accretion disk turbulence.

  8. A Gibbs potential expansion with a quantic system made up of a large number of particles

    International Nuclear Information System (INIS)

    Bloch, Claude; Dominicis, Cyrano de

    1959-01-01

    Starting from an expansion derived in a previous work, we study the contribution to the Gibbs potential of the two-body dynamical correlations, taking into account the statistical correlations. Such a contribution is of interest for low density systems at low temperature. In the zero density limit, it reduces to the Beth Uhlenbeck expression of the second virial coefficient. For a system of fermions in the zero temperature limit, it yields the contribution of the Brueckner reaction matrix to the ground state energy, plus, under certain conditions, additional terms of the form exp. (β |Δ|), where the Δ are the binding energies of 'bound states' of the type first discussed by L. Cooper. Finally, we study the wave function of two particles immersed in a medium (defined by its temperature and chemical potential). lt satisfies an equation generalizing the Bethe Goldstone equation for an arbitrary temperature. Reprint of a paper published in 'Nuclear Physics' 10, 1959, p. 181-196 [fr

  9. Dam risk reduction study for a number of large tailings dams in Ontario

    Energy Technology Data Exchange (ETDEWEB)

    Verma, N. [AMEC Earth and Environmental Ltd., Mississauga, ON (Canada); Small, A. [AMEC Earth and Environmental Ltd., Fredericton, NB (Canada); Martin, T. [AMEC Earth and Environmental, Burnaby, BC (Canada); Cacciotti, D. [AMEC Earth and Environmental Ltd., Sudbury, ON (Canada); Ross, T. [Vale Inco Ltd., Sudbury, ON (Canada)

    2009-07-01

    This paper discussed a risk reduction study conducted for 10 large tailings dams located at a central tailings facility in Ontario. Located near large industrial and urban developments, the tailings dams were built using an upstream method of construction that did not involve beach compaction or the provision of under-drainage. The study provided a historical background for the dam and presented results from investigations and instrumentation data. The methods used to develop the dam configurations were discussed, and remedial measures and risk assessment measures used on the dams were reviewed. The aim of the study was to address key sources of risk, which include the presence of high pore pressures and hydraulic gradients; the potential for liquefaction; slope instability; and the potential for overtopping. A borehole investigation was conducted and piezocone probes were used to obtain continuous data and determine soil and groundwater conditions. The study identified that the lower portion of the dam slopes were of concern. Erosion gullies could lead to larger scale failures, and elevated pore pressures could lead to the risk of seepage breakouts. It was concluded that remedial measures are now being conducted to ensure slope stability. 6 refs., 1 tab., 6 figs.

  10. EUPAN enables pan-genome studies of a large number of eukaryotic genomes.

    Science.gov (United States)

    Hu, Zhiqiang; Sun, Chen; Lu, Kuang-Chen; Chu, Xixia; Zhao, Yue; Lu, Jinyuan; Shi, Jianxin; Wei, Chaochun

    2017-08-01

    Pan-genome analyses are routinely carried out for bacteria to interpret the within-species gene presence/absence variations (PAVs). However, pan-genome analyses are rare for eukaryotes due to the large sizes and higher complexities of their genomes. Here we proposed EUPAN, a eukaryotic pan-genome analysis toolkit, enabling automatic large-scale eukaryotic pan-genome analyses and detection of gene PAVs at a relatively low sequencing depth. In the previous studies, we demonstrated the effectiveness and high accuracy of EUPAN in the pan-genome analysis of 453 rice genomes, in which we also revealed widespread gene PAVs among individual rice genomes. Moreover, EUPAN can be directly applied to the current re-sequencing projects primarily focusing on single nucleotide polymorphisms. EUPAN is implemented in Perl, R and C ++. It is supported under Linux and preferred for a computer cluster with LSF and SLURM job scheduling system. EUPAN together with its standard operating procedure (SOP) is freely available for non-commercial use (CC BY-NC 4.0) at http://cgm.sjtu.edu.cn/eupan/index.html . ccwei@sjtu.edu.cn or jianxin.shi@sjtu.edu.cn. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  11. Formation of free round jets with long laminar regions at large Reynolds numbers

    Science.gov (United States)

    Zayko, Julia; Teplovodskii, Sergey; Chicherina, Anastasia; Vedeneev, Vasily; Reshmin, Alexander

    2018-04-01

    The paper describes a new, simple method for the formation of free round jets with long laminar regions by a jet-forming device of ˜1.5 jet diameters in size. Submerged jets of 0.12 m diameter at Reynolds numbers of 2000-12 560 are experimentally studied. It is shown that for the optimal regime, the laminar region length reaches 5.5 diameters for Reynolds number ˜10 000 which is not achievable for other methods of laminar jet formation. To explain the existence of the optimal regime, a steady flow calculation in the forming unit and a stability analysis of outcoming jet velocity profiles are conducted. The shortening of the laminar regions, compared with the optimal regime, is explained by the higher incoming turbulence level for lower velocities and by the increase of perturbation growth rates for larger velocities. The initial laminar regions of free jets can be used for organising air curtains for the protection of objects in medicine and technologies by creating the air field with desired properties not mixed with ambient air. Free jets with long laminar regions can also be used for detailed studies of perturbation growth and transition to turbulence in round jets.

  12. Large scale statistics for computational verification of grain growth simulations with experiments

    International Nuclear Information System (INIS)

    Demirel, Melik C.; Kuprat, Andrew P.; George, Denise C.; Straub, G.K.; Misra, Amit; Alexander, Kathleen B.; Rollett, Anthony D.

    2002-01-01

    It is known that by controlling microstructural development, desirable properties of materials can be achieved. The main objective of our research is to understand and control interface dominated material properties, and finally, to verify experimental results with computer simulations. We have previously showed a strong similarity between small-scale grain growth experiments and anisotropic three-dimensional simulations obtained from the Electron Backscattered Diffraction (EBSD) measurements. Using the same technique, we obtained 5170-grain data from an Aluminum-film (120 (micro)m thick) with a columnar grain structure. Experimentally obtained starting microstructure and grain boundary properties are input for the three-dimensional grain growth simulation. In the computational model, minimization of the interface energy is the driving force for the grain boundary motion. The computed evolved microstructure is compared with the final experimental microstructure, after annealing at 550 C. Characterization of the structures and properties of grain boundary networks (GBN) to produce desirable microstructures is one of the fundamental problems in interface science. There is an ongoing research for the development of new experimental and analytical techniques in order to obtain and synthesize information related to GBN. The grain boundary energy and mobility data were characterized by Electron Backscattered Diffraction (EBSD) technique and Atomic Force Microscopy (AFM) observations (i.e., for ceramic MgO and for the metal Al). Grain boundary energies are extracted from triple junction (TJ) geometry considering the local equilibrium condition at TJ's. Relative boundary mobilities were also extracted from TJ's through a statistical/multiscale analysis. Additionally, there are recent theoretical developments of grain boundary evolution in microstructures. In this paper, a new technique for three-dimensional grain growth simulations was used to simulate interface migration

  13. Statistical macrodynamics of large dynamical systems. Case of a phase transition in oscillator communities

    International Nuclear Information System (INIS)

    Kuramoto, Y.; Nishikawa, I.

    1987-01-01

    A model dynamical system with a great many degrees of freedom is proposed for which the critical condition for the onset of collective oscillations, the evolution of a suitably defined order parameter, and its fluctuations around steady states can be studied analytically. This is a rotator model appropriate for a large population of limit cycle oscillators. It is assumed that the natural frequencies of the oscillators are distributed and that each oscillator interacts with all the others uniformly. An exact self-consistent equation for the stationary amplitude of the collective oscillation is derived and is extended to a dynamical form. This dynamical extension is carried out near the transition point where the characteristic time scales of the order parameter and of the individual oscillators become well separated from each other. The macroscopic evolution equation thus obtained generally involves a fluctuating term whose irregular temporal variation comes from a deterministic torus motion of a subpopulation. The analysis of this equation reveals order parameter behavior qualitatively different from that in thermodynamic phase transitions, especially in that the critical fluctuations in the present system are extremely small

  14. Application of Evolution Strategies to the Design of Tracking Filters with a Large Number of Specifications

    Directory of Open Access Journals (Sweden)

    Jesús García Herrero

    2003-07-01

    Full Text Available This paper describes the application of evolution strategies to the design of interacting multiple model (IMM tracking filters in order to fulfill a large table of performance specifications. These specifications define the desired filter performance in a thorough set of selected test scenarios, for different figures of merit and input conditions, imposing hundreds of performance goals. The design problem is stated as a numeric search in the filter parameters space to attain all specifications or at least minimize, in a compromise, the excess over some specifications as much as possible, applying global optimization techniques coming from evolutionary computation field. Besides, a new methodology is proposed to integrate specifications in a fitness function able to effectively guide the search to suitable solutions. The method has been applied to the design of an IMM tracker for a real-world civil air traffic control application: the accomplishment of specifications defined for the future European ARTAS system.

  15. Jet Impingement Heat Transfer at High Reynolds Numbers and Large Density Variations

    DEFF Research Database (Denmark)

    Jensen, Michael Vincent; Walther, Jens Honore

    2010-01-01

    Jet impingement heat transfer from a round gas jet to a flat wall has been investigated numerically in a configuration with H/D=2, where H is the distance from the jet inlet to the wall and D is the jet diameter. The jet Reynolds number was 361000 and the density ratio across the wall boundary...... layer was 3.3 due to a substantial temperature difference of 1600K between jet and wall. Results are presented which indicate very high heat flux levels and it is demonstrated that the jet inlet turbulence intensity significantly influences the heat transfer results, especially in the stagnation region....... The results also show a noticeable difference in the heat transfer predictions when applying different turbulence models. Furthermore calculations were performed to study the effect of applying temperature dependent thermophysical properties versus constant properties and the effect of calculating the gas...

  16. On the strong law of large numbers for $\\varphi$-subgaussian random variables

    OpenAIRE

    Zajkowski, Krzysztof

    2016-01-01

    For $p\\ge 1$ let $\\varphi_p(x)=x^2/2$ if $|x|\\le 1$ and $\\varphi_p(x)=1/p|x|^p-1/p+1/2$ if $|x|>1$. For a random variable $\\xi$ let $\\tau_{\\varphi_p}(\\xi)$ denote $\\inf\\{a\\ge 0:\\;\\forall_{\\lambda\\in\\mathbb{R}}\\; \\ln\\mathbb{E}\\exp(\\lambda\\xi)\\le\\varphi_p(a\\lambda)\\}$; $\\tau_{\\varphi_p}$ is a norm in a space $Sub_{\\varphi_p}=\\{\\xi:\\;\\tau_{\\varphi_p}(\\xi)1$) there exist positive constants $c$ and $\\alpha$ such that for every natural number $n$ the following inequality $\\tau_{\\varphi_p}(\\sum_{i=1...

  17. Large boson number IBM calculations and their relationship to the Bohr model

    International Nuclear Information System (INIS)

    Thiamova, G.; Rowe, D.J.

    2009-01-01

    Recently, the SO(5) Clebsch-Gordan (CG) coefficients up to the seniority v max =40 were computed in floating point arithmetic (T.A. Welsh, unpublished (2008)); and, in exact arithmetic, as square roots of rational numbers (M.A. Caprio et al., to be published in Comput. Phys. Commun.). It is shown in this paper that extending the QQQ model calculations set up in the work by D.J. Rowe and G. Thiamova (Nucl. Phys. A 760, 59 (2005)) to N=v max =40 is sufficient to obtain the IBM results converged to its Bohr contraction limit. This will be done by comparing some important matrix elements in both models, by looking at the seniority decomposition of low-lying states and at the behavior of the energy and B(E2) transition strengths ratios with increasing seniority. (orig.)

  18. A comparison of three approaches to compute the effective Reynolds number of the implicit large-eddy simulations

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Ye [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Thornber, Ben [The Univ. of Sydney, Sydney, NSW (Australia)

    2016-04-12

    Here, the implicit large-eddy simulation (ILES) has been utilized as an effective approach for calculating many complex flows at high Reynolds number flows. Richtmyer–Meshkov instability (RMI) induced flow can be viewed as a homogeneous decaying turbulence (HDT) after the passage of the shock. In this article, a critical evaluation of three methods for estimating the effective Reynolds number and the effective kinematic viscosity is undertaken utilizing high-resolution ILES data. Effective Reynolds numbers based on the vorticity and dissipation rate, or the integral and inner-viscous length scales, are found to be the most self-consistent when compared to the expected phenomenology and wind tunnel experiments.

  19. Slepian simulation of distributions of plastic displacements of earthquake excited shear frames with a large number of stories

    DEFF Research Database (Denmark)

    Lazarov, Boyan Stefanov; Ditlevsen, Ove

    2005-01-01

    The object of study is a stationary Gaussian white noise excited plane multistory shear frame with a large number of rigid traverses. All the traverse-connecting columns have finite symmetrical yield limits except the columns in one or more of the bottom floors. The columns behave linearly elasti...

  20. Introduction to the spectral distribution method. Application example to the subspaces with a large number of quasi particles

    International Nuclear Information System (INIS)

    Arvieu, R.

    The assumptions and principles of the spectral distribution method are reviewed. The object of the method is to deduce information on the nuclear spectra by constructing a frequency function which has the same first few moments, as the exact frequency function, these moments being then exactly calculated. The method is applied to subspaces containing a large number of quasi particles [fr

  1. Strong Law of Large Numbers for Hidden Markov Chains Indexed by an Infinite Tree with Uniformly Bounded Degrees

    Directory of Open Access Journals (Sweden)

    Huilin Huang

    2014-01-01

    Full Text Available We study strong limit theorems for hidden Markov chains fields indexed by an infinite tree with uniformly bounded degrees. We mainly establish the strong law of large numbers for hidden Markov chains fields indexed by an infinite tree with uniformly bounded degrees and give the strong limit law of the conditional sample entropy rate.

  2. Hydrodynamic interaction on large-Reynolds-number aligned bubbles: Drag effects

    International Nuclear Information System (INIS)

    Ramirez-Munoz, J.; Salinas-Rodriguez, E.; Soria, A.; Gama-Goicochea, A.

    2011-01-01

    Graphical abstract: Display Omitted Highlights: → The hydrodynamic interaction of a pair aligned equal-sized bubbles is analyzed. → The leading bubble wake decreases the drag on the trailing bubble. → A new semi-analytical model for the trailing bubble's drag is presented. → The equilibrium distance between bubbles is predicted. - Abstract: The hydrodynamic interaction of two equal-sized spherical gas bubbles rising along a vertical line with a Reynolds number (Re) between 50 and 200 is analyzed. An approach to estimate the trailing bubble drag based on the search of a proper reference fluid velocity is proposed. Our main result is a new, simple semi-analytical model for the trailing bubble drag. Additionally, the equilibrium separation distance between bubbles is predicted. The proposed models agree quantitatively up to small distances between bubbles, with reported data for 50 ≤ Re ≤ 200. The relative average error for the trailing bubble drag, Er, is found to be in the range 1.1 ≤ Er ≤ 1.7, i.e., it is of the same order of the analytical predictions in the literature.

  3. Hydrodynamic interaction on large-Reynolds-number aligned bubbles: Drag effects

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez-Munoz, J., E-mail: jrm@correo.azc.uam.mx [Departamento de Energia, Universidad Autonoma Metropolitana-Azcapotzalco, Av. San Pablo 180, Col. Reynosa Tamaulipas, 02200 Mexico D.F. (Mexico); Centro de Investigacion en Polimeros, Marcos Achar Lobaton No. 2, Tepexpan, 55885 Acolman, Edo. de Mexico (Mexico); Salinas-Rodriguez, E.; Soria, A. [Departamento de IPH, Universidad Autonoma Metropolitana-Iztapalapa, San Rafael Atlixco 186, Col. Vicentina, Iztapalapa, 09340 Mexico D.F. (Mexico); Gama-Goicochea, A. [Centro de Investigacion en Polimeros, Marcos Achar Lobaton No. 2, Tepexpan, 55885 Acolman, Edo. de Mexico (Mexico)

    2011-07-15

    Graphical abstract: Display Omitted Highlights: > The hydrodynamic interaction of a pair aligned equal-sized bubbles is analyzed. > The leading bubble wake decreases the drag on the trailing bubble. > A new semi-analytical model for the trailing bubble's drag is presented. > The equilibrium distance between bubbles is predicted. - Abstract: The hydrodynamic interaction of two equal-sized spherical gas bubbles rising along a vertical line with a Reynolds number (Re) between 50 and 200 is analyzed. An approach to estimate the trailing bubble drag based on the search of a proper reference fluid velocity is proposed. Our main result is a new, simple semi-analytical model for the trailing bubble drag. Additionally, the equilibrium separation distance between bubbles is predicted. The proposed models agree quantitatively up to small distances between bubbles, with reported data for 50 {<=} Re {<=} 200. The relative average error for the trailing bubble drag, Er, is found to be in the range 1.1 {<=} Er {<=} 1.7, i.e., it is of the same order of the analytical predictions in the literature.

  4. KISCH / UL AND DURABLE DEVELOPMENT OF THE REGIONS THAT HAVE A LARGE NUMBER OF RELIGIOUS SETTLEMENTS

    Directory of Open Access Journals (Sweden)

    ENEA CONSTANTA

    2016-06-01

    Full Text Available We live in a world of contemporary kitsch, a world that merges authentic and false, good taste and meets often with bad taste. This phenomenon is găseseşte everywhere: in art, in literature cheap in media productions, shows, dialogues streets, in homes, in politics, in other words, in everyday life. Ksch site came directly in tourism, being identified in all forms of tourism worldwide, but especially religious tourism, pilgrimage with unexpected success in recent years. This paper makes an analysis of progressive evolution tourist traffic religion on the ability of the destination of religious tourism to remain competitive against all the problems, to attract visitors for their loyalty, to remain unique in terms of cultural and be a permanent balance with the environment, taking into account the environment religious phenomenon invaded Kisch, it disgraceful mixing dangerously with authentic spirituality. How trade, and rather Kisch's commercial components affect the environment, reflected in terms of religious tourism offer representatives highlighted based on a survey of major monastic ensembles in North Oltenia. Research objectives achieved in work followed, on the one hand the contributions and effects of the high number of visitors on the regions that hold religious sites, and on the other hand weighting and effects of commercial activity carried out in or near monastic establishments, be it genuine or kisck the respective regions. The study conducted took into account the northern region of Oltenia, and where demand for tourism is predominantly oriented exclusively practicing religious tourism

  5. Secondary organic aerosol formation from a large number of reactive man-made organic compounds

    Energy Technology Data Exchange (ETDEWEB)

    Derwent, Richard G., E-mail: r.derwent@btopenworld.com [rdscientific, Newbury, Berkshire (United Kingdom); Jenkin, Michael E. [Atmospheric Chemistry Services, Okehampton, Devon (United Kingdom); Utembe, Steven R.; Shallcross, Dudley E. [School of Chemistry, University of Bristol, Bristol (United Kingdom); Murrells, Tim P.; Passant, Neil R. [AEA Environment and Energy, Harwell International Business Centre, Oxon (United Kingdom)

    2010-07-15

    A photochemical trajectory model has been used to examine the relative propensities of a wide variety of volatile organic compounds (VOCs) emitted by human activities to form secondary organic aerosol (SOA) under one set of highly idealised conditions representing northwest Europe. This study applied a detailed speciated VOC emission inventory and the Master Chemical Mechanism version 3.1 (MCM v3.1) gas phase chemistry, coupled with an optimised representation of gas-aerosol absorptive partitioning of 365 oxygenated chemical reaction product species. In all, SOA formation was estimated from the atmospheric oxidation of 113 emitted VOCs. A number of aromatic compounds, together with some alkanes and terpenes, showed significant propensities to form SOA. When these propensities were folded into a detailed speciated emission inventory, 15 organic compounds together accounted for 97% of the SOA formation potential of UK man made VOC emissions and 30 emission source categories accounted for 87% of this potential. After road transport and the chemical industry, SOA formation was dominated by the solvents sector which accounted for 28% of the SOA formation potential.

  6. Normal zone detectors for a large number of inductively coupled coils

    International Nuclear Information System (INIS)

    Owen, E.W.; Shimer, D.W.

    1983-01-01

    In order to protect a set of inductively coupled superconducting magnets, it is necessary to locate and measure normal zone voltages that are small compared with the mutual and self-induced voltages. The method described in this paper uses two sets of voltage measurements to locate and measure one or more normal zones in any number of coupled coils. One set of voltages is the outputs of bridges that balance out the self-induced voltages. The other set of voltages can be the voltages across the coils, although alternatives are possible. The two sets of equations form a single combined set of equations. Each normal zone location or combination of normal zones has a set of these combined equations associated with it. It is demonstrated that the normal zone can be located and the correct set chosen, allowing determination of the size of the normal zone. Only a few operations take place in a working detector: multiplication of a constant, addition, and simple decision-making. In many cases the detector for each coil, although weakly linked to the other detectors, can be considered to be independent

  7. Normal zone detectors for a large number of inductively coupled coils. Revision 1

    International Nuclear Information System (INIS)

    Owen, E.W.; Shimer, D.W.

    1983-01-01

    In order to protect a set of inductively coupled superconducting magnets, it is necessary to locate and measure normal zone voltages that are small compared with the mutual and self-induced voltages. The method described in this paper uses two sets of voltage measurements to locate and measure one or more normal zones in any number of coupled coils. One set of voltages is the outputs of bridges that balance out the self-induced voltages. The other set of voltages can be the voltages across the coils, although alternatives are possible. The two sets of equations form a single combined set of equations. Each normal zone location or combination of normal zones has a set of these combined equations associated with it. It is demonstrated that the normal zone can be located and the correct set chosen, allowing determination of the size of the normal zone. Only a few operations take place in a working detector: multiplication of a constant, addition, and simple decision-making. In many cases the detector for each coil, although weakly linked to the other detectors, can be considered to be independent. The effect on accuracy of changes in the system parameters is discussed

  8. Normal zone detectors for a large number of inductively coupled coils

    International Nuclear Information System (INIS)

    Owen, E.W.; Shimer, D.W.

    1983-01-01

    In order to protect a set of inductively coupled superconducting magnets, it is necessary to locate and measure normal zone voltages that are small compared with the mutual and self-induced voltages. The method described in this report uses two sets of voltage measurements to locate and measure one or more normal zones in any number of coupled coils. One set of voltages is the outputs of bridges that balance out the self-induced voltages The other set of voltages can be the voltages across the coils, although alternatives are possible. The two sets of equations form a single combined set of equations. Each normal zone location or combination of normal zones has a set of these combined equations associated with it. It is demonstrated that the normal zone can be located and the correct set chosen, allowing determination of the size of the normal zone. Only a few operations take plae in a working detector: multiplication of a constant, addition, and simple decision-making. In many cases the detector for each coil, although weakly linked to the other detectors, can be considered to be independent. An example of the detector design is given for four coils with realistic parameters. The effect on accuracy of changes in the system parameters is discussed

  9. Statistical analyses of scatterplots to identify important factors in large-scale simulations, 1: Review and comparison of techniques

    International Nuclear Information System (INIS)

    Kleijnen, J.P.C.; Helton, J.C.

    1999-01-01

    Procedures for identifying patterns in scatterplots generated in Monte Carlo sensitivity analyses are described and illustrated. These procedures attempt to detect increasingly complex patterns in scatterplots and involve the identification of (i) linear relationships with correlation coefficients, (ii) monotonic relationships with rank correlation coefficients, (iii) trends in central tendency as defined by means, medians and the Kruskal-Wallis statistic, (iv) trends in variability as defined by variances and interquartile ranges, and (v) deviations from randomness as defined by the chi-square statistic. A sequence of example analyses with a large model for two-phase fluid flow illustrates how the individual procedures can differ in the variables that they identify as having effects on particular model outcomes. The example analyses indicate that the use of a sequence of procedures is a good analysis strategy and provides some assurance that an important effect is not overlooked

  10. Beating the numbers through strategic intervention materials (SIMs): Innovative science teaching for large classes

    Science.gov (United States)

    Alboruto, Venus M.

    2017-05-01

    The study aimed to find out the effectiveness of using Strategic Intervention Materials (SIMs) as an innovative teaching practice in managing large Grade Eight Science classes to raise the performance of the students in terms of science process skills development and mastery of science concepts. Utilizing experimental research design with two groups of participants, which were purposefully chosen, it was obtained that there existed a significant difference in the performance of the experimental and control groups based on actual class observation and written tests on science process skills with a p-value of 0.0360 in favor of the experimental class. Further, results of written pre-test and post-test on science concepts showed that the experimental group with the mean of 24.325 (SD =3.82) performed better than the control group with the mean of 20.58 (SD =4.94), with a registered p-value of 0.00039. Therefore, the use of SIMs significantly contributed to the mastery of science concepts and the development of science process skills. Based on the findings, the following recommendations are offered: 1. that grade eight science teachers should use or adopt the SIMs used in this study to improve their students' performance; 2. training-workshop on developing SIMs must be conducted to help teachers develop SIMs to be used in their classes; 3. school administrators must allocate funds for the development and reproduction of SIMs to be used by the students in their school; and 4. every division should have a repository of SIMs for easy access of the teachers in the entire division.

  11. Detection of large numbers of novel sequences in the metatranscriptomes of complex marine microbial communities.

    Science.gov (United States)

    Gilbert, Jack A; Field, Dawn; Huang, Ying; Edwards, Rob; Li, Weizhong; Gilna, Paul; Joint, Ian

    2008-08-22

    Sequencing the expressed genetic information of an ecosystem (metatranscriptome) can provide information about the response of organisms to varying environmental conditions. Until recently, metatranscriptomics has been limited to microarray technology and random cloning methodologies. The application of high-throughput sequencing technology is now enabling access to both known and previously unknown transcripts in natural communities. We present a study of a complex marine metatranscriptome obtained from random whole-community mRNA using the GS-FLX Pyrosequencing technology. Eight samples, four DNA and four mRNA, were processed from two time points in a controlled coastal ocean mesocosm study (Bergen, Norway) involving an induced phytoplankton bloom producing a total of 323,161,989 base pairs. Our study confirms the finding of the first published metatranscriptomic studies of marine and soil environments that metatranscriptomics targets highly expressed sequences which are frequently novel. Our alternative methodology increases the range of experimental options available for conducting such studies and is characterized by an exceptional enrichment of mRNA (99.92%) versus ribosomal RNA. Analysis of corresponding metagenomes confirms much higher levels of assembly in the metatranscriptomic samples and a far higher yield of large gene families with >100 members, approximately 91% of which were novel. This study provides further evidence that metatranscriptomic studies of natural microbial communities are not only feasible, but when paired with metagenomic data sets, offer an unprecedented opportunity to explore both structure and function of microbial communities--if we can overcome the challenges of elucidating the functions of so many never-seen-before gene families.

  12. Pre-Statistical Process Control: Making Numbers Count! JobLink Winning at Work Instructor's Manual, Module 3.

    Science.gov (United States)

    Coast Community Coll. District, Costa Mesa, CA.

    This instructor's manual for workplace trainers contains the materials required to conduct a course in pre-statistical process control. The course consists of six lessons for workers and two lessons for supervisors that discuss the following: concepts taught in the six lessons; workers' progress in the individual lessons; and strategies for…

  13. What caused a large number of fatalities in the Tohoku earthquake?

    Science.gov (United States)

    Ando, M.; Ishida, M.; Nishikawa, Y.; Mizuki, C.; Hayashi, Y.

    2012-04-01

    The Mw9.0 earthquake caused 20,000 deaths and missing persons in northeastern Japan. 115 years prior to this event, there were three historical tsunamis that struck the region, one of which is a "tsunami earthquake" resulted with a death toll of 22,000. Since then, numerous breakwaters were constructed along the entire northeastern coasts and tsunami evacuation drills were carried out and hazard maps were distributed to local residents on numerous communities. However, despite the constructions and preparedness efforts, the March 11 Tohoku earthquake caused numerous fatalities. The strong shaking lasted three minutes or longer, thus all residents recognized that this is the strongest and longest earthquake that they had been ever experienced in their lives. The tsunami inundated an enormous area at about 560km2 over 35 cities along the coast of northeast Japan. To find out the reasons behind the high number of fatalities due to the March 11 tsunami, we interviewed 150 tsunami survivors at public evacuation shelters in 7 cities mainly in Iwate prefecture in mid-April and early June 2011. Interviews were done for about 30min or longer focused on their evacuation behaviors and those that they had observed. On the basis of the interviews, we found that residents' decisions not to evacuate immediately were partly due to or influenced by earthquake science results. Below are some of the factors that affected residents' decisions. 1. Earthquake hazard assessments turned out to be incorrect. Expected earthquake magnitudes and resultant hazards in northeastern Japan assessed and publicized by the government were significantly smaller than the actual Tohoku earthquake. 2. Many residents did not receive accurate tsunami warnings. The first tsunami warning were too small compared with the actual tsunami heights. 3. The previous frequent warnings with overestimated tsunami height influenced the behavior of the residents. 4. Many local residents above 55 years old experienced

  14. EFFECT OF MEASUREMENT ERRORS ON PREDICTED COSMOLOGICAL CONSTRAINTS FROM SHEAR PEAK STATISTICS WITH LARGE SYNOPTIC SURVEY TELESCOPE

    Energy Technology Data Exchange (ETDEWEB)

    Bard, D.; Chang, C.; Kahn, S. M.; Gilmore, K.; Marshall, S. [KIPAC, Stanford University, 452 Lomita Mall, Stanford, CA 94309 (United States); Kratochvil, J. M.; Huffenberger, K. M. [Department of Physics, University of Miami, Coral Gables, FL 33124 (United States); May, M. [Physics Department, Brookhaven National Laboratory, Upton, NY 11973 (United States); AlSayyad, Y.; Connolly, A.; Gibson, R. R.; Jones, L.; Krughoff, S. [Department of Astronomy, University of Washington, Seattle, WA 98195 (United States); Ahmad, Z.; Bankert, J.; Grace, E.; Hannel, M.; Lorenz, S. [Department of Physics, Purdue University, West Lafayette, IN 47907 (United States); Haiman, Z.; Jernigan, J. G., E-mail: djbard@slac.stanford.edu [Department of Astronomy and Astrophysics, Columbia University, New York, NY 10027 (United States); and others

    2013-09-01

    We study the effect of galaxy shape measurement errors on predicted cosmological constraints from the statistics of shear peak counts with the Large Synoptic Survey Telescope (LSST). We use the LSST Image Simulator in combination with cosmological N-body simulations to model realistic shear maps for different cosmological models. We include both galaxy shape noise and, for the first time, measurement errors on galaxy shapes. We find that the measurement errors considered have relatively little impact on the constraining power of shear peak counts for LSST.

  15. Effects of Turbulent Reynolds Number on the Displacement Speed Statistics in the Thin Reaction Zones Regime of Turbulent Premixed Combustion

    Directory of Open Access Journals (Sweden)

    Nilanjan Chakraborty

    2011-01-01

    nature of the correlations remains unaffected. The dependence of displacement speed on strain rate and curvature is found to weaken with increasing turbulent Reynolds number when either Damköhler or Karlovitz number is held constant, but the qualitative nature of the correlation remains unaltered. The implications of turbulent Reynolds number effects in the context of Flame Surface Density (FSD modelling have also been addressed, with emphasis on the influence of displacement speed on the curvature and propagation terms in the FSD balance equation.

  16. Modelling high Reynolds number wall-turbulence interactions in laboratory experiments using large-scale free-stream turbulence.

    Science.gov (United States)

    Dogan, Eda; Hearst, R Jason; Ganapathisubramani, Bharathram

    2017-03-13

    A turbulent boundary layer subjected to free-stream turbulence is investigated in order to ascertain the scale interactions that dominate the near-wall region. The results are discussed in relation to a canonical high Reynolds number turbulent boundary layer because previous studies have reported considerable similarities between these two flows. Measurements were acquired simultaneously from four hot wires mounted to a rake which was traversed through the boundary layer. Particular focus is given to two main features of both canonical high Reynolds number boundary layers and boundary layers subjected to free-stream turbulence: (i) the footprint of the large scales in the logarithmic region on the near-wall small scales, specifically the modulating interaction between these scales, and (ii) the phase difference in amplitude modulation. The potential for a turbulent boundary layer subjected to free-stream turbulence to 'simulate' high Reynolds number wall-turbulence interactions is discussed. The results of this study have encouraging implications for future investigations of the fundamental scale interactions that take place in high Reynolds number flows as it demonstrates that these can be achieved at typical laboratory scales.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).

  17. Statistical analyses of scatterplots to identify important factors in large-scale simulations, 2: robustness of techniques

    International Nuclear Information System (INIS)

    Kleijnen, J.P.C.; Helton, J.C.

    1999-01-01

    The robustness of procedures for identifying patterns in scatterplots generated in Monte Carlo sensitivity analyses is investigated. These procedures are based on attempts to detect increasingly complex patterns in the scatterplots under consideration and involve the identification of (i) linear relationships with correlation coefficients, (ii) monotonic relationships with rank correlation coefficients, (iii) trends in central tendency as defined by means, medians and the Kruskal-Wallis statistic, (iv) trends in variability as defined by variances and interquartile ranges, and (v) deviations from randomness as defined by the chi-square statistic. The following two topics related to the robustness of these procedures are considered for a sequence of example analyses with a large model for two-phase fluid flow: the presence of Type I and Type II errors, and the stability of results obtained with independent Latin hypercube samples. Observations from analysis include: (i) Type I errors are unavoidable, (ii) Type II errors can occur when inappropriate analysis procedures are used, (iii) physical explanations should always be sought for why statistical procedures identify variables as being important, and (iv) the identification of important variables tends to be stable for independent Latin hypercube samples

  18. Global statistics of liquid water content and effective number density of water clouds over ocean derived from combined CALIPSO and MODIS measurements

    Science.gov (United States)

    Hu, Y.; Vaughan, M.; McClain, C.; Behrenfeld, M.; Maring, H.; Anderson, D.; Sun-Mack, S.; Flittner, D.; Huang, J.; Wielicki, B.; Minnis, P.; Weimer, C.; Trepte, C.; Kuehn, R.

    2007-03-01

    This study presents an empirical relation that links layer integrated depolarization ratios, the extinction coefficients, and effective radii of water clouds, based on Monte Carlo simulations of CALIPSO lidar observations. Combined with cloud effective radius retrieved from MODIS, cloud liquid water content and effective number density of water clouds are estimated from CALIPSO lidar depolarization measurements in this study. Global statistics of the cloud liquid water content and effective number density are presented.

  19. Recreating Raven's: software for systematically generating large numbers of Raven-like matrix problems with normed properties.

    Science.gov (United States)

    Matzen, Laura E; Benz, Zachary O; Dixon, Kevin R; Posey, Jamie; Kroger, James K; Speed, Ann E

    2010-05-01

    Raven's Progressive Matrices is a widely used test for assessing intelligence and reasoning ability (Raven, Court, & Raven, 1998). Since the test is nonverbal, it can be applied to many different populations and has been used all over the world (Court & Raven, 1995). However, relatively few matrices are in the sets developed by Raven, which limits their use in experiments requiring large numbers of stimuli. For the present study, we analyzed the types of relations that appear in Raven's original Standard Progressive Matrices (SPMs) and created a software tool that can combine the same types of relations according to parameters chosen by the experimenter, to produce very large numbers of matrix problems with specific properties. We then conducted a norming study in which the matrices we generated were compared with the actual SPMs. This study showed that the generated matrices both covered and expanded on the range of problem difficulties provided by the SPMs.

  20. Strong Law of Large Numbers for Countable Markov Chains Indexed by an Infinite Tree with Uniformly Bounded Degree

    Directory of Open Access Journals (Sweden)

    Bao Wang

    2014-01-01

    Full Text Available We study the strong law of large numbers for the frequencies of occurrence of states and ordered couples of states for countable Markov chains indexed by an infinite tree with uniformly bounded degree, which extends the corresponding results of countable Markov chains indexed by a Cayley tree and generalizes the relative results of finite Markov chains indexed by a uniformly bounded tree.

  1. Statistical analysis of the phytocoenose homogeneity. IV. Species number and mean biomass value as functions of the area size

    Directory of Open Access Journals (Sweden)

    Anna J. Kwiatkowska

    2014-01-01

    Full Text Available Homogeneity of the Leocobryo-Pineturn phytocoenose was assessed on the grounds of the effect of area size on the species number and mean biomass value. It was confirmed that: I species number was a logarithmic function of the area size; 2 relation of individual species biomass to the area size was, as a rule, other than rectilinear, 3 the size of phytocoenose floristicly representative area differed from that determined with respect to the standing biomass and 4 phytocoenose homogeneity is related to the scale defined by the size of representative area.

  2. On the statistical aspects of sunspot number time series and its association with the summer-monsoon rainfall over India

    Science.gov (United States)

    Chattopadhyay, Surajit; Chattopadhyay, Goutami

    The present paper reports studies on the association between the mean annual sunspot numbers and the summer monsoon rainfall over India. The cross correlations have been studied. After Box-Cox transformation, the time spectral analysis has been executed and it has been found that both of the time series have an important spectrum at the fifth harmonic. An artificial neural network (ANN) model has been developed on the data series averaged continuously by five years and the neural network could establish a predictor-predict and relationship between the sunspot numbers and the mean yearly summer monsoon rainfall over India.

  3. Determining the number of components in principal components analysis: A comparison of statistical, crossvalidation and approximated methods

    NARCIS (Netherlands)

    Saccenti, E.; Camacho, J.

    2015-01-01

    Principal component analysis is one of the most commonly used multivariate tools to describe and summarize data. Determining the optimal number of components in a principal component model is a fundamental problem in many fields of application. In this paper we compare the performance of several

  4. On the Required Number of Antennas in a Point-to-Point Large-but-Finite MIMO System

    KAUST Repository

    Makki, Behrooz; Svensson, Tommy; Eriksson, Thomas; Alouini, Mohamed-Slim

    2015-01-01

    In this paper, we investigate the performance of the point-to-point multiple-input-multiple-output (MIMO) systems in the presence of a large but finite numbers of antennas at the transmitters and/or receivers. Considering the cases with and without hybrid automatic repeat request (HARQ) feedback, we determine the minimum numbers of the transmit/receive antennas which are required to satisfy different outage probability constraints. We study the effect of the spatial correlation between the antennas on the system performance. Also, the required number of antennas are obtained for different fading conditions. Our results show that different outage requirements can be satisfied with relatively few transmit/receive antennas. © 2015 IEEE.

  5. On the Required Number of Antennas in a Point-to-Point Large-but-Finite MIMO System

    KAUST Repository

    Makki, Behrooz

    2015-11-12

    In this paper, we investigate the performance of the point-to-point multiple-input-multiple-output (MIMO) systems in the presence of a large but finite numbers of antennas at the transmitters and/or receivers. Considering the cases with and without hybrid automatic repeat request (HARQ) feedback, we determine the minimum numbers of the transmit/receive antennas which are required to satisfy different outage probability constraints. We study the effect of the spatial correlation between the antennas on the system performance. Also, the required number of antennas are obtained for different fading conditions. Our results show that different outage requirements can be satisfied with relatively few transmit/receive antennas. © 2015 IEEE.

  6. Direct and large eddy simulation of turbulent heat transfer at very low Prandtl number: Application to lead–bismuth flows

    International Nuclear Information System (INIS)

    Bricteux, L.; Duponcheel, M.; Winckelmans, G.; Tiselj, I.; Bartosiewicz, Y.

    2012-01-01

    Highlights: ► We perform direct and hybrid-large eddy simulations of high Reynolds and low Prandtl turbulent wall-bounded flows with heat transfer. ► We use a state-of-the-art numerical methods with low energy dissipation and low dispersion. ► We use recent multiscalesubgrid scale models. ► Important results concerning the establishment of near wall modeling strategy in RANS are provided. ► The turbulent Prandtl number that is predicted by our simulation is different than that proposed by some correlations of the literature. - Abstract: This paper deals with the issue of modeling convective turbulent heat transfer of a liquid metal with a Prandtl number down to 0.01, which is the order of magnitude of lead–bismuth eutectic in a liquid metal reactor. This work presents a DNS (direct numerical simulation) and a LES (large eddy simulation) of a channel flow at two different Reynolds numbers, and the results are analyzed in the frame of best practice guidelines for RANS (Reynolds averaged Navier–Stokes) computations used in industrial applications. They primarily show that the turbulent Prandtl number concept should be used with care and that even recent proposed correlations may not be sufficient.

  7. The number of degrees of freedom for statistical distribution of s wave reduced neutron width for several nuclei

    International Nuclear Information System (INIS)

    Zhixiang, Z.

    1983-01-01

    The least squares fit has been performed using chi-squared distribution function for all available evaluated data for s-wave reduced neutron width of several nuclei. The number of degrees of freedom and average value have been obtained. The missing levels of weak s-wave resonances and extra p-wave levels have been taken into account, if any. For 75 As and 103 Rh, s-wave population has been separated by Bayes' theorem before making fit. The results thus obtained are consistent with Porter-Thomas distribution, i.e., chi-squared distribution with γ=1, as one would expect. It has not been found in this work that the number of degrees of freedom for the distribution of s-wave reduced neutron width might be greater than one as reported by H.C.Sharma et al. (1976) at the international conference on interactions of neutrons with nuclei. (Auth.)

  8. Evaluation of Origin Ensemble algorithm for image reconstruction for pixelated solid-state detectors with large number of channels

    Science.gov (United States)

    Kolstein, M.; De Lorenzo, G.; Mikhaylova, E.; Chmeissani, M.; Ariño, G.; Calderón, Y.; Ozsahin, I.; Uzun, D.

    2013-04-01

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For PET scanners, conventional algorithms like Filtered Back-Projection (FBP) and Ordered Subset Expectation Maximization (OSEM) are straightforward to use and give good results. However, FBP presents difficulties for detectors with limited angular coverage like PEM and Compton gamma cameras, whereas OSEM has an impractically large time and memory consumption for a Compton gamma camera with a large number of channels. In this article, the Origin Ensemble (OE) algorithm is evaluated as an alternative algorithm for image reconstruction. Monte Carlo simulations of the PET design are used to compare the performance of OE, FBP and OSEM in terms of the bias, variance and average mean squared error (MSE) image quality metrics. For the PEM and Compton camera designs, results obtained with OE are presented.

  9. A Multilayer Secure Biomedical Data Management System for Remotely Managing a Very Large Number of Diverse Personal Healthcare Devices

    Directory of Open Access Journals (Sweden)

    KeeHyun Park

    2015-01-01

    Full Text Available In this paper, a multilayer secure biomedical data management system for managing a very large number of diverse personal health devices is proposed. The system has the following characteristics: the system supports international standard communication protocols to achieve interoperability. The system is integrated in the sense that both a PHD communication system and a remote PHD management system work together as a single system. Finally, the system proposed in this paper provides user/message authentication processes to securely transmit biomedical data measured by PHDs based on the concept of a biomedical signature. Some experiments, including the stress test, have been conducted to show that the system proposed/constructed in this study performs very well even when a very large number of PHDs are used. For a stress test, up to 1,200 threads are made to represent the same number of PHD agents. The loss ratio of the ISO/IEEE 11073 messages in the normal system is as high as 14% when 1,200 PHD agents are connected. On the other hand, no message loss occurs in the multilayered system proposed in this study, which demonstrates the superiority of the multilayered system to the normal system with regard to heavy traffic.

  10. Long-range correlations, geometrical structure, and transport properties of macromolecular solutions. The equivalence of configurational statistics and geometrodynamics of large molecules.

    Science.gov (United States)

    Mezzasalma, Stefano A

    2007-12-04

    A special theory of Brownian relativity was previously proposed to describe the universal picture arising in ideal polymer solutions. In brief, it redefines a Gaussian macromolecule in a 4-dimensional diffusive spacetime, establishing a (weak) Lorentz-Poincaré invariance between liquid and polymer Einstein's laws for Brownian movement. Here, aimed at inquiring into the effect of correlations, we deepen the extension of the special theory to a general formulation. The previous statistical equivalence, for dynamic trajectories of liquid molecules and static configurations of macromolecules, and rather obvious in uncorrelated systems, is enlarged by a more general principle of equivalence, for configurational statistics and geometrodynamics. Accordingly, the three geodesic motion, continuity, and field equations could be rewritten, and a number of scaling behaviors were recovered in a spacetime endowed with general static isotropic metric (i.e., for equilibrium polymer solutions). We also dealt with universality in the volume fraction and, unexpectedly, found that a hyperscaling relation of the form, (average size) x (diffusivity) x (viscosity)1/2 ~f(N0, phi0) is fulfilled in several regimes, both in the chain monomer number (N) and polymer volume fraction (phi). Entangled macromolecular dynamics was treated as a geodesic light deflection, entaglements acting in close analogy to the field generated by a spherically symmetric mass source, where length fluctuations of the chain primitive path behave as azimuth fluctuations of its shape. Finally, the general transformation rule for translational and diffusive frames gives a coordinate gauge invariance, suggesting a widened Lorentz-Poincaré symmetry for Brownian statistics. We expect this approach to find effective applications to solutions of arbitrarily large molecules displaying a variety of structures, where the effect of geometry is more explicit and significant in itself (e.g., surfactants, lipids, proteins).

  11. An Efficient and Reliable Statistical Method for Estimating Functional Connectivity in Large Scale Brain Networks Using Partial Correlation.

    Science.gov (United States)

    Wang, Yikai; Kang, Jian; Kemmer, Phebe B; Guo, Ying

    2016-01-01

    Currently, network-oriented analysis of fMRI data has become an important tool for understanding brain organization and brain networks. Among the range of network modeling methods, partial correlation has shown great promises in accurately detecting true brain network connections. However, the application of partial correlation in investigating brain connectivity, especially in large-scale brain networks, has been limited so far due to the technical challenges in its estimation. In this paper, we propose an efficient and reliable statistical method for estimating partial correlation in large-scale brain network modeling. Our method derives partial correlation based on the precision matrix estimated via Constrained L1-minimization Approach (CLIME), which is a recently developed statistical method that is more efficient and demonstrates better performance than the existing methods. To help select an appropriate tuning parameter for sparsity control in the network estimation, we propose a new Dens-based selection method that provides a more informative and flexible tool to allow the users to select the tuning parameter based on the desired sparsity level. Another appealing feature of the Dens-based method is that it is much faster than the existing methods, which provides an important advantage in neuroimaging applications. Simulation studies show that the Dens-based method demonstrates comparable or better performance with respect to the existing methods in network estimation. We applied the proposed partial correlation method to investigate resting state functional connectivity using rs-fMRI data from the Philadelphia Neurodevelopmental Cohort (PNC) study. Our results show that partial correlation analysis removed considerable between-module marginal connections identified by full correlation analysis, suggesting these connections were likely caused by global effects or common connection to other nodes. Based on partial correlation, we find that the most significant

  12. Slepian simulation of distributions of plastic displacements of earthquake excited shear frames with a large number of stories

    DEFF Research Database (Denmark)

    Lazarov, Boyan Stefanov; Ditlevsen, Ove

    2005-01-01

    The object of study is a stationary Gaussian white noise excited plane multistory shear frame with a large number of rigid traverses. All the traverse-connecting columns have finite symmetrical yield limits except the columns in one or more of the bottom floors. The columns behave linearly elastic...... within the yield limits and ideally plastic outside these without accumulating eigenstresses. Within the elastic domain the frame is modeled as a linearly damped oscillator. The white noise excitation acts on the mass of the first floor making the movement of the elastic bottom floors simulate a ground...

  13. Atomic Number Dependence of Hadron Production at Large Transverse Momentum in 300 GeV Proton--Nucleus Collisions

    Science.gov (United States)

    Cronin, J. W.; Frisch, H. J.; Shochet, M. J.; Boymond, J. P.; Mermod, R.; Piroue, P. A.; Sumner, R. L.

    1974-07-15

    In an experiment at the Fermi National Accelerator Laboratory we have compared the production of large transverse momentum hadrons from targets of W, Ti, and Be bombarded by 300 GeV protons. The hadron yields were measured at 90 degrees in the proton-nucleon c.m. system with a magnetic spectrometer equipped with 2 Cerenkov counters and a hadron calorimeter. The production cross-sections have a dependence on the atomic number A that grows with P{sub 1}, eventually leveling off proportional to A{sup 1.1}.

  14. Summary of experience from a large number of construction inspections; Wind power plant projects; Erfarenhetsaaterfoering fraan entreprenadbesiktningar

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Bertil; Holmberg, Rikard

    2010-08-15

    This report presents a summary of experience from a large number of construction inspections of wind power projects. The working method is based on the collection of construction experience in form of questionnaires. The questionnaires were supplemented by a number of in-depth interviews to understand more in detail what is perceived to be a problem and if there were suggestions for improvements. The results in this report is based on inspection protocols from 174 wind turbines, which corresponds to about one-third of the power plants built in the time period. In total the questionnaires included 4683 inspection remarks as well as about one hundred free text comments. 52 of the 174 inspected power stations were rejected, corresponding to 30%. It has not been possible to identify any over represented type of remark as a main cause of rejection, but the rejection is usually based on a total number of remarks that is too large. The average number of remarks for a power plant is 27. Most power stations have between 20 and 35 remarks. The most common remarks concern shortcomings in marking and documentation. These are easily adjusted, and may be regarded as less serious. There are, however, a number of remarks which are recurrent and quite serious, mainly regarding gearbox, education and lightning protection. Usually these are also easily adjusted, but the consequences if not corrected can be very large. The consequences may be either shortened life of expensive components, e.g. oil problems in gear boxes, or increased probability of serious accidents, e.g. maladjusted lightning protection. In the report, comparison between power stations with various construction period, size, supplier, geography and topography is also presented. The general conclusion is that the differences are small. The results of the evaluation of questionnaires correspond well with the result of the in-depth interviews with clients. The problem that clients agreed upon as the greatest is the lack

  15. Effect of Small Numbers of Test Results on Accuracy of Hoek-Brown Strength Parameter Estimations: A Statistical Simulation Study

    Science.gov (United States)

    Bozorgzadeh, Nezam; Yanagimura, Yoko; Harrison, John P.

    2017-12-01

    The Hoek-Brown empirical strength criterion for intact rock is widely used as the basis for estimating the strength of rock masses. Estimations of the intact rock H-B parameters, namely the empirical constant m and the uniaxial compressive strength σc, are commonly obtained by fitting the criterion to triaxial strength data sets of small sample size. This paper investigates how such small sample sizes affect the uncertainty associated with the H-B parameter estimations. We use Monte Carlo (MC) simulation to generate data sets of different sizes and different combinations of H-B parameters, and then investigate the uncertainty in H-B parameters estimated from these limited data sets. We show that the uncertainties depend not only on the level of variability but also on the particular combination of parameters being investigated. As particular combinations of H-B parameters can informally be considered to represent specific rock types, we discuss that as the minimum number of required samples depends on rock type it should correspond to some acceptable level of uncertainty in the estimations. Also, a comparison of the results from our analysis with actual rock strength data shows that the probability of obtaining reliable strength parameter estimations using small samples may be very low. We further discuss the impact of this on ongoing implementation of reliability-based design protocols and conclude with suggestions for improvements in this respect.

  16. Global statistics of liquid water content and effective number concentration of water clouds over ocean derived from combined CALIPSO and MODIS measurements

    Science.gov (United States)

    Hu, Y.; Vaughan, M.; McClain, C.; Behrenfeld, M.; Maring, H.; Anderson, D.; Sun-Mack, S.; Flittner, D.; Huang, J.; Wielicki, B.; Minnis, P.; Weimer, C.; Trepte, C.; Kuehn, R.

    2007-06-01

    This study presents an empirical relation that links the volume extinction coefficients of water clouds, the layer integrated depolarization ratios measured by lidar, and the effective radii of water clouds derived from collocated passive sensor observations. Based on Monte Carlo simulations of CALIPSO lidar observations, this method combines the cloud effective radius reported by MODIS with the lidar depolarization ratios measured by CALIPSO to estimate both the liquid water content and the effective number concentration of water clouds. The method is applied to collocated CALIPSO and MODIS measurements obtained during July and October of 2006, and January 2007. Global statistics of the cloud liquid water content and effective number concentration are presented.

  17. Global statistics of liquid water content and effective number density of water clouds over ocean derived from combined CALIPSO and MODIS measurements

    OpenAIRE

    Y. Hu; M. Vaughan; C. McClain; M. Behrenfeld; H. Maring; D. Anderson; S. Sun-Mack; D. Flittner; J. Huang; B. Wielicki; P. Minnis; C. Weimer; C. Trepte; R. Kuehn

    2007-01-01

    International audience; This study presents an empirical relation that links layer integrated depolarization ratios, the extinction coefficients, and effective radii of water clouds, based on Monte Carlo simulations of CALIPSO lidar observations. Combined with cloud effective radius retrieved from MODIS, cloud liquid water content and effective number density of water clouds are estimated from CALIPSO lidar depolarization measurements in this study. Global statistics of the cloud liquid water...

  18. On the Use of Educational Numbers: Comparative Constructions of Hierarchies by Means of Large-Scale Assessments

    Directory of Open Access Journals (Sweden)

    Daniel Pettersson

    2016-01-01

    later the growing importance of transnational agencies and international, regional and national assessments. How to reference this article Pettersson, D., Popkewitz, T. S., & Lindblad, S. (2016. On the Use of Educational Numbers: Comparative Constructions of Hierarchies by Means of Large-Scale Assessments. Espacio, Tiempo y Educación, 3(1, 177-202. doi: http://dx.doi.org/10.14516/ete.2016.003.001.10

  19. A Genome-Wide Association Study in Large White and Landrace Pig Populations for Number Piglets Born Alive

    Science.gov (United States)

    Bergfelder-Drüing, Sarah; Grosse-Brinkhaus, Christine; Lind, Bianca; Erbe, Malena; Schellander, Karl; Simianer, Henner; Tholen, Ernst

    2015-01-01

    The number of piglets born alive (NBA) per litter is one of the most important traits in pig breeding due to its influence on production efficiency. It is difficult to improve NBA because the heritability of the trait is low and it is governed by a high number of loci with low to moderate effects. To clarify the biological and genetic background of NBA, genome-wide association studies (GWAS) were performed using 4,012 Large White and Landrace pigs from herdbook and commercial breeding companies in Germany (3), Austria (1) and Switzerland (1). The animals were genotyped with the Illumina PorcineSNP60 BeadChip. Because of population stratifications within and between breeds, clusters were formed using the genetic distances between the populations. Five clusters for each breed were formed and analysed by GWAS approaches. In total, 17 different significant markers affecting NBA were found in regions with known effects on female reproduction. No overlapping significant chromosome areas or QTL between Large White and Landrace breed were detected. PMID:25781935

  20. A genome-wide association study in large white and landrace pig populations for number piglets born alive.

    Directory of Open Access Journals (Sweden)

    Sarah Bergfelder-Drüing

    Full Text Available The number of piglets born alive (NBA per litter is one of the most important traits in pig breeding due to its influence on production efficiency. It is difficult to improve NBA because the heritability of the trait is low and it is governed by a high number of loci with low to moderate effects. To clarify the biological and genetic background of NBA, genome-wide association studies (GWAS were performed using 4,012 Large White and Landrace pigs from herdbook and commercial breeding companies in Germany (3, Austria (1 and Switzerland (1. The animals were genotyped with the Illumina PorcineSNP60 BeadChip. Because of population stratifications within and between breeds, clusters were formed using the genetic distances between the populations. Five clusters for each breed were formed and analysed by GWAS approaches. In total, 17 different significant markers affecting NBA were found in regions with known effects on female reproduction. No overlapping significant chromosome areas or QTL between Large White and Landrace breed were detected.

  1. Application of a statistical software package for analysis of large patient dose data sets obtained from RIS

    International Nuclear Information System (INIS)

    Fazakerley, J.; Charnock, P.; Wilde, R.; Jones, R.; Ward, M.

    2010-01-01

    For the purpose of patient dose audit, clinical audit and radiology workload analysis, data from Radiology Information Systems (RIS) at many hospitals are collected using a database and the analysis was automated using a statistical package and Visual Basic coding. The database is a Structured Query Language database, which can be queried using an off-the-shelf statistical package, Statistica. Macros were created to automatically format the data to a consistent format between different hospitals ready for analysis. These macros can also be used to automate further analysis such as detailing mean kV, mAs and entrance surface dose per room and per gender. Standard deviation and standard error of the mean are also generated. Graphs can also be generated to illustrate the trends in doses between different variables such as room and gender. Collectively, this information can be used to generate a report. A process that once could take up to 1 d to complete now takes around 1 h. A major benefit in providing the service to hospital trusts is that less resource is now required to report on RIS data, making the possibility of continuous dose audit more likely. Time that was spent on sorting through data can now be spent on improving the analysis to provide benefit to the customer. Using data sets from RIS is a good way to perform dose audits as the huge numbers of data available provide the bases for very accurate analysis. Using macros written in Statistica Visual Basic has helped sort and consistently analyse these data. Being able to analyse by exposure factors has provided a more detailed report to the customer. (authors)

  2. Turbulent Flow Over Large Roughness Elements: Effect of Frontal and Plan Solidity on Turbulence Statistics and Structure

    Science.gov (United States)

    Placidi, M.; Ganapathisubramani, B.

    2018-04-01

    Wind-tunnel experiments were carried out on fully-rough boundary layers with large roughness (δ /h ≈ 10, where h is the height of the roughness elements and δ is the boundary-layer thickness). Twelve different surface conditions were created by using LEGO™ bricks of uniform height. Six cases are tested for a fixed plan solidity (λ _P) with variations in frontal density (λ _F), while the other six cases have varying λ _P for fixed λ _F. Particle image velocimetry and floating-element drag-balance measurements were performed. The current results complement those contained in Placidi and Ganapathisubramani (J Fluid Mech 782:541-566, 2015), extending the previous analysis to the turbulence statistics and spatial structure. Results indicate that mean velocity profiles in defect form agree with Townsend's similarity hypothesis with varying λ _F, however, the agreement is worse for cases with varying λ _P. The streamwise and wall-normal turbulent stresses, as well as the Reynolds shear stresses, show a lack of similarity across most examined cases. This suggests that the critical height of the roughness for which outer-layer similarity holds depends not only on the height of the roughness, but also on the local wall morphology. A new criterion based on shelter solidity, defined as the sheltered plan area per unit wall-parallel area, which is similar to the `effective shelter area' in Raupach and Shaw (Boundary-Layer Meteorol 22:79-90, 1982), is found to capture the departure of the turbulence statistics from outer-layer similarity. Despite this lack of similarity reported in the turbulence statistics, proper orthogonal decomposition analysis, as well as two-point spatial correlations, show that some form of universal flow structure is present, as all cases exhibit virtually identical proper orthogonal decomposition mode shapes and correlation fields. Finally, reduced models based on proper orthogonal decomposition reveal that the small scales of the turbulence

  3. Part 2. Development of Enhanced Statistical Methods for Assessing Health Effects Associated with an Unknown Number of Major Sources of Multiple Air Pollutants.

    Science.gov (United States)

    Park, Eun Sug; Symanski, Elaine; Han, Daikwon; Spiegelman, Clifford

    2015-06-01

    A major difficulty with assessing source-specific health effects is that source-specific exposures cannot be measured directly; rather, they need to be estimated by a source-apportionment method such as multivariate receptor modeling. The uncertainty in source apportionment (uncertainty in source-specific exposure estimates and model uncertainty due to the unknown number of sources and identifiability conditions) has been largely ignored in previous studies. Also, spatial dependence of multipollutant data collected from multiple monitoring sites has not yet been incorporated into multivariate receptor modeling. The objectives of this project are (1) to develop a multipollutant approach that incorporates both sources of uncertainty in source-apportionment into the assessment of source-specific health effects and (2) to develop enhanced multivariate receptor models that can account for spatial correlations in the multipollutant data collected from multiple sites. We employed a Bayesian hierarchical modeling framework consisting of multivariate receptor models, health-effects models, and a hierarchical model on latent source contributions. For the health model, we focused on the time-series design in this project. Each combination of number of sources and identifiability conditions (additional constraints on model parameters) defines a different model. We built a set of plausible models with extensive exploratory data analyses and with information from previous studies, and then computed posterior model probability to estimate model uncertainty. Parameter estimation and model uncertainty estimation were implemented simultaneously by Markov chain Monte Carlo (MCMC*) methods. We validated the methods using simulated data. We illustrated the methods using PM2.5 (particulate matter ≤ 2.5 μm in aerodynamic diameter) speciation data and mortality data from Phoenix, Arizona, and Houston, Texas. The Phoenix data included counts of cardiovascular deaths and daily PM2

  4. Book Trade Research and Statistics. Prices of U.S. and Foreign Published Materials; Book Title Output and Average Prices: 2001 Final and 2002 Preliminary Figures; Book Sales Statistics, 2002: AAP Preliminary Estimates; U.S. Book Exports and Imports:2002; Number of Book Outlets in the United States and Canada; Review Media Statistics.

    Science.gov (United States)

    Sullivan, Sharon G.; Grabois, Andrew; Greco, Albert N.

    2003-01-01

    Includes six reports related to book trade statistics, including prices of U.S. and foreign materials; book title output and average prices; book sales statistics; book exports and imports; book outlets in the U.S. and Canada; and numbers of books and other media reviewed by major reviewing publications. (LRW)

  5. Analysis of a large number of clinical studies for breast cancer radiotherapy: estimation of radiobiological parameters for treatment planning

    International Nuclear Information System (INIS)

    Guerrero, M; Li, X Allen

    2003-01-01

    Numerous studies of early-stage breast cancer treated with breast conserving surgery (BCS) and radiotherapy (RT) have been published in recent years. Both external beam radiotherapy (EBRT) and/or brachytherapy (BT) with different fractionation schemes are currently used. The present RT practice is largely based on empirical experience and it lacks a reliable modelling tool to compare different RT modalities or to design new treatment strategies. The purpose of this work is to derive a plausible set of radiobiological parameters that can be used for RT treatment planning. The derivation is based on existing clinical data and is consistent with the analysis of a large number of published clinical studies on early-stage breast cancer. A large number of published clinical studies on the treatment of early breast cancer with BCS plus RT (including whole breast EBRT with or without a boost to the tumour bed, whole breast EBRT alone, brachytherapy alone) and RT alone are compiled and analysed. The linear quadratic (LQ) model is used in the analysis. Three of these clinical studies are selected to derive a plausible set of LQ parameters. The potential doubling time is set a priori in the derivation according to in vitro measurements from the literature. The impact of considering lower or higher T pot is investigated. The effects of inhomogeneous dose distributions are considered using clinically representative dose volume histograms. The derived LQ parameters are used to compare a large number of clinical studies using different regimes (e.g., RT modality and/or different fractionation schemes with different prescribed dose) in order to validate their applicability. The values of the equivalent uniform dose (EUD) and biologically effective dose (BED) are used as a common metric to compare the biological effectiveness of each treatment regime. We have obtained a plausible set of radiobiological parameters for breast cancer. This set of parameters is consistent with in vitro

  6. Statistical Analysis and validation

    NARCIS (Netherlands)

    Hoefsloot, H.C.J.; Horvatovich, P.; Bischoff, R.

    2013-01-01

    In this chapter guidelines are given for the selection of a few biomarker candidates from a large number of compounds with a relative low number of samples. The main concepts concerning the statistical validation of the search for biomarkers are discussed. These complicated methods and concepts are

  7. Extracting climate signals from large hydrological data cubes using multivariate statistics - an example for the Mediterranean basin

    Science.gov (United States)

    Kauer, Agnes; Dorigo, Wouter; Bauer-Marschallinger, Bernhard

    2017-04-01

    Global warming is expected to change ocean-atmosphere oscillation patterns, e.g. the El Nino Southern Oscillation, and may thus have a substantial impact on water resources over land. Yet, the link between climate oscillations and terrestrial hydrology has large uncertainties. In particular, the climate in the Mediterranean basin is expected to be sensitive to global warming as it may increase insufficient and irregular water supply and lead to more frequent and intense droughts and heavy precipitation events. The ever increasing need for water in tourism and agriculture reinforce the problem. Therefore, the monitoring and better understanding of the hydrological cycle are crucial for this area. This study seeks to quantify the effect of regional climate modes, e.g. the Northern Atlantic Oscillation (NAO) on the hydrological cycle in the Mediterranean. We apply Empirical Orthogonal Functions (EOF) to a wide range of hydrological datasets to extract the major modes of variation over the study period. We use more than ten datasets describing precipitation, soil moisture, evapotranspiration, and changes in water mass with study periods ranging from one to three decades depending on the dataset. The resulting EOFs are then examined for correlations with regional climate modes using Spearman rank correlation analysis. This is done for the entire time span of the EOFs and for monthly and seasonally sampled data. We find relationships between the hydrological datasets and the climate modes NAO, Arctic Oscillation (AO), Eastern Atlantic (EA), and Tropical Northern Atlantic (TNA). Analyses of monthly and seasonally sampled data reveal high correlations especially in the winter months. However, the spatial extent of the data cube considered for the analyses have a large impact on the results. Our statistical analyses suggest an impact of regional climate modes on the hydrological cycle in the Mediterranean area and may provide valuable input for evaluating process

  8. Statistical model for the mechanical behavior of the tissue engineering non-woven fibrous matrices under large deformation.

    Science.gov (United States)

    Rizvi, Mohd Suhail; Pal, Anupam

    2014-09-01

    The fibrous matrices are widely used as scaffolds for the regeneration of load-bearing tissues due to their structural and mechanical similarities with the fibrous components of the extracellular matrix. These scaffolds not only provide the appropriate microenvironment for the residing cells but also act as medium for the transmission of the mechanical stimuli, essential for the tissue regeneration, from macroscopic scale of the scaffolds to the microscopic scale of cells. The requirement of the mechanical loading for the tissue regeneration requires the fibrous scaffolds to be able to sustain the complex three-dimensional mechanical loading conditions. In order to gain insight into the mechanical behavior of the fibrous matrices under large amount of elongation as well as shear, a statistical model has been formulated to study the macroscopic mechanical behavior of the electrospun fibrous matrix and the transmission of the mechanical stimuli from scaffolds to the cells via the constituting fibers. The study establishes the load-deformation relationships for the fibrous matrices for different structural parameters. It also quantifies the changes in the fiber arrangement and tension generated in the fibers with the deformation of the matrix. The model reveals that the tension generated in the fibers on matrix deformation is not homogeneous and hence the cells located in different regions of the fibrous scaffold might experience different mechanical stimuli. The mechanical response of fibrous matrices was also found to be dependent on the aspect ratio of the matrix. Therefore, the model establishes a structure-mechanics interdependence of the fibrous matrices under large deformation, which can be utilized in identifying the appropriate structure and external mechanical loading conditions for the regeneration of load-bearing tissues. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Small genomes and large seeds: chromosome numbers, genome size and seed mass in diploid Aesculus species (Sapindaceae).

    Science.gov (United States)

    Krahulcová, Anna; Trávnícek, Pavel; Krahulec, František; Rejmánek, Marcel

    2017-04-01

    Aesculus L. (horse chestnut, buckeye) is a genus of 12-19 extant woody species native to the temperate Northern Hemisphere. This genus is known for unusually large seeds among angiosperms. While chromosome counts are available for many Aesculus species, only one has had its genome size measured. The aim of this study is to provide more genome size data and analyse the relationship between genome size and seed mass in this genus. Chromosome numbers in root tip cuttings were confirmed for four species and reported for the first time for three additional species. Flow cytometric measurements of 2C nuclear DNA values were conducted on eight species, and mean seed mass values were estimated for the same taxa. The same chromosome number, 2 n = 40, was determined in all investigated taxa. Original measurements of 2C values for seven Aesculus species (eight taxa), added to just one reliable datum for A. hippocastanum , confirmed the notion that the genome size in this genus with relatively large seeds is surprisingly low, ranging from 0·955 pg 2C -1 in A. parviflora to 1·275 pg 2C -1 in A. glabra var. glabra. The chromosome number of 2 n = 40 seems to be conclusively the universal 2 n number for non-hybrid species in this genus. Aesculus genome sizes are relatively small, not only within its own family, Sapindaceae, but also within woody angiosperms. The genome sizes seem to be distinct and non-overlapping among the four major Aesculus clades. These results provide an extra support for the most recent reconstruction of Aesculus phylogeny. The correlation between the 2C values and seed masses in examined Aesculus species is slightly negative and not significant. However, when the four major clades are treated separately, there is consistent positive association between larger genome size and larger seed mass within individual lineages. © The Author 2017. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For

  10. Statistical searches for microlensing events in large, non-uniformly sampled time-domain surveys: A test using palomar transient factory data

    Energy Technology Data Exchange (ETDEWEB)

    Price-Whelan, Adrian M.; Agüeros, Marcel A. [Department of Astronomy, Columbia University, 550 W 120th Street, New York, NY 10027 (United States); Fournier, Amanda P. [Department of Physics, Broida Hall, University of California, Santa Barbara, CA 93106 (United States); Street, Rachel [Las Cumbres Observatory Global Telescope Network, Inc., 6740 Cortona Drive, Suite 102, Santa Barbara, CA 93117 (United States); Ofek, Eran O. [Benoziyo Center for Astrophysics, Weizmann Institute of Science, 76100 Rehovot (Israel); Covey, Kevin R. [Lowell Observatory, 1400 West Mars Hill Road, Flagstaff, AZ 86001 (United States); Levitan, David; Sesar, Branimir [Division of Physics, Mathematics, and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Laher, Russ R.; Surace, Jason, E-mail: adrn@astro.columbia.edu [Spitzer Science Center, California Institute of Technology, Mail Stop 314-6, Pasadena, CA 91125 (United States)

    2014-01-20

    Many photometric time-domain surveys are driven by specific goals, such as searches for supernovae or transiting exoplanets, which set the cadence with which fields are re-imaged. In the case of the Palomar Transient Factory (PTF), several sub-surveys are conducted in parallel, leading to non-uniform sampling over its ∼20,000 deg{sup 2} footprint. While the median 7.26 deg{sup 2} PTF field has been imaged ∼40 times in the R band, ∼2300 deg{sup 2} have been observed >100 times. We use PTF data to study the trade off between searching for microlensing events in a survey whose footprint is much larger than that of typical microlensing searches, but with far-from-optimal time sampling. To examine the probability that microlensing events can be recovered in these data, we test statistics used on uniformly sampled data to identify variables and transients. We find that the von Neumann ratio performs best for identifying simulated microlensing events in our data. We develop a selection method using this statistic and apply it to data from fields with >10 R-band observations, 1.1 × 10{sup 9} light curves, uncovering three candidate microlensing events. We lack simultaneous, multi-color photometry to confirm these as microlensing events. However, their number is consistent with predictions for the event rate in the PTF footprint over the survey's three years of operations, as estimated from near-field microlensing models. This work can help constrain all-sky event rate predictions and tests microlensing signal recovery in large data sets, which will be useful to future time-domain surveys, such as that planned with the Large Synoptic Survey Telescope.

  11. Evaluation of two sweeping methods for estimating the number of immature Aedes aegypti (Diptera: Culicidae in large containers

    Directory of Open Access Journals (Sweden)

    Margareth Regina Dibo

    2013-07-01

    Full Text Available Introduction Here, we evaluated sweeping methods used to estimate the number of immature Aedes aegypti in large containers. Methods III/IV instars and pupae at a 9:1 ratio were placed in three types of containers with, each one with three different water levels. Two sweeping methods were tested: water-surface sweeping and five-sweep netting. The data were analyzed using linear regression. Results The five-sweep netting technique was more suitable for drums and water-tanks, while the water-surface sweeping method provided the best results for swimming pools. Conclusions Both sweeping methods are useful tools in epidemiological surveillance programs for the control of Aedes aegypti.

  12. Production of large number of water-cooled excitation coils with improved techniques for multipole magnets of INDUS -2

    International Nuclear Information System (INIS)

    Karmarkar, M.G.; Sreeramulu, K.; Kulshreshta, P.K.

    2003-01-01

    Accelerator multipole magnets are characterized by high field gradients powered with relatively high current excitation coils. Due to space limitations in the magnet core/poles, compact coil geometry is also necessary. The coils are made of several insulated turns using hollow copper conductor. High current densities in these require cooling with low conductivity water. Additionally during operation, these are subjected to thermal fatigue stresses. A large number of coils ( Qty: 650 nos.) having different geometries were required for all multipole magnets like quadrupole (QP), sextupole (SP). Improved techniques for winding, insulation and epoxy consolidation were developed in-house at M D Lab and all coils have been successfully made. Improved technology, production techniques adopted for magnet coils and their inspection are briefly discussed in this paper. (author)

  13. Product-selective blot: a technique for measuring enzyme activities in large numbers of samples and in native electrophoresis gels

    International Nuclear Information System (INIS)

    Thompson, G.A.; Davies, H.M.; McDonald, N.

    1985-01-01

    A method termed product-selective blotting has been developed for screening large numbers of samples for enzyme activity. The technique is particularly well suited to detection of enzymes in native electrophoresis gels. The principle of the method was demonstrated by blotting samples from glutaminase or glutamate synthase reactions into an agarose gel embedded with ion-exchange resin under conditions favoring binding of product (glutamate) over substrates and other substances in the reaction mixture. After washes to remove these unbound substances, the product was measured using either fluorometric staining or radiometric techniques. Glutaminase activity in native electrophoresis gels was visualized by a related procedure in which substrates and products from reactions run in the electrophoresis gel were blotted directly into a resin-containing image gel. Considering the selective-binding materials available for use in the image gel, along with the possible detection systems, this method has potentially broad application

  14. CrossRef Large numbers of cold positronium atoms created in laser-selected Rydberg states using resonant charge exchange

    CERN Document Server

    McConnell, R; Kolthammer, WS; Richerme, P; Müllers, A; Walz, J; Grzonka, D; Zielinski, M; Fitzakerley, D; George, MC; Hessels, EA; Storry, CH; Weel, M

    2016-01-01

    Lasers are used to control the production of highly excited positronium atoms (Ps*). The laser light excites Cs atoms to Rydberg states that have a large cross section for resonant charge-exchange collisions with cold trapped positrons. For each trial with 30 million trapped positrons, more than 700 000 of the created Ps* have trajectories near the axis of the apparatus, and are detected using Stark ionization. This number of Ps* is 500 times higher than realized in an earlier proof-of-principle demonstration (2004 Phys. Lett. B 597 257). A second charge exchange of these near-axis Ps* with trapped antiprotons could be used to produce cold antihydrogen, and this antihydrogen production is expected to be increased by a similar factor.

  15. A very large number of GABAergic neurons are activated in the tuberal hypothalamus during paradoxical (REM sleep hypersomnia.

    Directory of Open Access Journals (Sweden)

    Emilie Sapin

    Full Text Available We recently discovered, using Fos immunostaining, that the tuberal and mammillary hypothalamus contain a massive population of neurons specifically activated during paradoxical sleep (PS hypersomnia. We further showed that some of the activated neurons of the tuberal hypothalamus express the melanin concentrating hormone (MCH neuropeptide and that icv injection of MCH induces a strong increase in PS quantity. However, the chemical nature of the majority of the neurons activated during PS had not been characterized. To determine whether these neurons are GABAergic, we combined in situ hybridization of GAD(67 mRNA with immunohistochemical detection of Fos in control, PS deprived and PS hypersomniac rats. We found that 74% of the very large population of Fos-labeled neurons located in the tuberal hypothalamus after PS hypersomnia were GAD-positive. We further demonstrated combining MCH immunohistochemistry and GAD(67in situ hybridization that 85% of the MCH neurons were also GAD-positive. Finally, based on the number of Fos-ir/GAD(+, Fos-ir/MCH(+, and GAD(+/MCH(+ double-labeled neurons counted from three sets of double-staining, we uncovered that around 80% of the large number of the Fos-ir/GAD(+ neurons located in the tuberal hypothalamus after PS hypersomnia do not contain MCH. Based on these and previous results, we propose that the non-MCH Fos/GABAergic neuronal population could be involved in PS induction and maintenance while the Fos/MCH/GABAergic neurons could be involved in the homeostatic regulation of PS. Further investigations will be needed to corroborate this original hypothesis.

  16. Eosinophils may play regionally disparate roles in influencing IgA(+) plasma cell numbers during large and small intestinal inflammation.

    Science.gov (United States)

    Forman, Ruth; Bramhall, Michael; Logunova, Larisa; Svensson-Frej, Marcus; Cruickshank, Sheena M; Else, Kathryn J

    2016-05-31

    Eosinophils are innate immune cells present in the intestine during steady state conditions. An intestinal eosinophilia is a hallmark of many infections and an accumulation of eosinophils is also observed in the intestine during inflammatory disorders. Classically the function of eosinophils has been associated with tissue destruction, due to the release of cytotoxic granule contents. However, recent evidence has demonstrated that the eosinophil plays a more diverse role in the immune system than previously acknowledged, including shaping adaptive immune responses and providing plasma cell survival factors during the steady state. Importantly, it is known that there are regional differences in the underlying immunology of the small and large intestine, but whether there are differences in context of the intestinal eosinophil in the steady state or inflammation is not known. Our data demonstrates that there are fewer IgA(+) plasma cells in the small intestine of eosinophil-deficient ΔdblGATA-1 mice compared to eosinophil-sufficient wild-type mice, with the difference becoming significant post-infection with Toxoplasma gondii. Remarkably, and in complete contrast, the absence of eosinophils in the inflamed large intestine does not impact on IgA(+) cell numbers during steady state, and is associated with a significant increase in IgA(+) cells post-infection with Trichuris muris compared to wild-type mice. Thus, the intestinal eosinophil appears to be less important in sustaining the IgA(+) cell pool in the large intestine compared to the small intestine, and in fact, our data suggests eosinophils play an inhibitory role. The dichotomy in the influence of the eosinophil over small and large intestinal IgA(+) cells did not depend on differences in plasma cell growth factors, recruitment potential or proliferation within the different regions of the gastrointestinal tract (GIT). We demonstrate for the first time that there are regional differences in the requirement of

  17. Investigating the Variability in Cumulus Cloud Number as a Function of Subdomain Size and Organization using large-domain LES

    Science.gov (United States)

    Neggers, R.

    2017-12-01

    Recent advances in supercomputing have introduced a "grey zone" in the representation of cumulus convection in general circulation models, in which this process is partially resolved. Cumulus parameterizations need to be made scale-aware and scale-adaptive to be able to conceptually and practically deal with this situation. A potential way forward are schemes formulated in terms of discretized Cloud Size Densities, or CSDs. Advantages include i) the introduction of scale-awareness at the foundation of the scheme, and ii) the possibility to apply size-filtering of parameterized convective transport and clouds. The CSD is a new variable that requires closure; this concerns its shape, its range, but also variability in cloud number that can appear due to i) subsampling effects and ii) organization in a cloud field. The goal of this study is to gain insight by means of sub-domain analyses of various large-domain LES realizations of cumulus cloud populations. For a series of three-dimensional snapshots, each with a different degree of organization, the cloud size distribution is calculated in all subdomains, for a range of subdomain sizes. The standard deviation of the number of clouds of a certain size is found to decrease with the subdomain size, following a powerlaw scaling corresponding to an inverse-linear dependence. Cloud number variability also increases with cloud size; this reflects that subsampling affects the largest clouds first, due to their typically larger neighbor spacing. Rewriting this dependence in terms of two dimensionless groups, by dividing by cloud number and cloud size respectively, yields a data collapse. Organization in the cloud field is found to act on top of this primary dependence, by enhancing the cloud number variability at the smaller sizes. This behavior reflects that small clouds start to "live" on top of larger structures such as cold pools, favoring or inhibiting their formation (as illustrated by the attached figure of cloud mask

  18. The necessity of and policy suggestions for implementing a limited number of large scale, fully integrated CCS demonstrations in China

    International Nuclear Information System (INIS)

    Li Zheng; Zhang Dongjie; Ma Linwei; West, Logan; Ni Weidou

    2011-01-01

    CCS is seen as an important and strategic technology option for China to reduce its CO 2 emission, and has received tremendous attention both around the world and in China. Scholars are divided on the role CCS should play, making the future of CCS in China highly uncertain. This paper presents the overall circumstances for CCS development in China, including the threats and opportunities for large scale deployment of CCS, the initial barriers and advantages that China currently possesses, as well as the current progress of CCS demonstration in China. The paper proposes the implementation of a limited number of larger scale, fully integrated CCS demonstration projects and explains the potential benefits that could be garnered. The problems with China's current CCS demonstration work are analyzed, and some targeted policies are proposed based on those observations. These policy suggestions can effectively solve these problems, help China gain the benefits with CCS demonstration soon, and make great contributions to China's big CO 2 reduction mission. - Highlights: → We analyze the overall circumstances for CCS development in China in detail. → China can garner multiple benefits by conducting several large, integrated CCS demos. → We present the current progress in CCS demonstration in China in detail. → Some problems exist with China's current CCS demonstration work. → Some focused policies are suggested to improve CCS demonstration in China.

  19. Law of large numbers for the SIR model with random vertex weights on Erdős-Rényi graph

    Science.gov (United States)

    Xue, Xiaofeng

    2017-11-01

    In this paper we are concerned with the SIR model with random vertex weights on Erdős-Rényi graph G(n , p) . The Erdős-Rényi graph G(n , p) is generated from the complete graph Cn with n vertices through independently deleting each edge with probability (1 - p) . We assign i. i. d. copies of a positive r. v. ρ on each vertex as the vertex weights. For the SIR model, each vertex is in one of the three states 'susceptible', 'infective' and 'removed'. An infective vertex infects a given susceptible neighbor at rate proportional to the production of the weights of these two vertices. An infective vertex becomes removed at a constant rate. A removed vertex will never be infected again. We assume that at t = 0 there is no removed vertex and the number of infective vertices follows a Bernoulli distribution B(n , θ) . Our main result is a law of large numbers of the model. We give two deterministic functions HS(ψt) ,HV(ψt) for t ≥ 0 and show that for any t ≥ 0, HS(ψt) is the limit proportion of susceptible vertices and HV(ψt) is the limit of the mean capability of an infective vertex to infect a given susceptible neighbor at moment t as n grows to infinity.

  20. Explaining the large numbers by a hierarchy of ''universes'': a unified theory of strong and gravitational interactions

    International Nuclear Information System (INIS)

    Caldirola, P.; Recami, E.

    1978-01-01

    By assuming covariance of physical laws under (discrete) dilatations, strong and gravitational interactions have been described in a unified way. In terms of the (additional, discrete) ''dilatational'' degree of freedom, our cosmos as well as hadrons can be considered as different states of the same system, or rather as similar systems. Moreover, a discrete hierarchy can be defined of ''universes'' which are governed by force fields with strengths inversely proportional to the ''universe'' radii. Inside each ''universe'' an equivalence principle holds, so that its characteristic field can be geometrized there. It is thus easy to derive a whole ''numerology'', i.e. relations among numbers analogous to the so-called Weyl-Eddington-Dirac ''large numbers''. For instance, the ''Planck mass'' happens to be nothing but the (average) magnitude of the strong charge of the hadron quarks. However, our ''numerology'' connects the (gravitational) macrocosmos with the (strong) microcosmos, rather than with the electromagnetic ones (as, e.g., in Dirac's version). Einstein-type scaled equations (with ''cosmological'' term) are suggested for the hadron interior, which - incidentally - yield a (classical) quark confinement in a very natural way and are compatible with the ''asymptotic freedom''. At last, within a ''bi-scale'' theory, further equations are proposed that provide a priori a classical field theory of strong interactions (between different hadrons). The relevant sections are 5.2, 7 and 8. (author)

  1. Modification of the large-scale features of high Reynolds number wall turbulence by passive surface obtrusions

    Energy Technology Data Exchange (ETDEWEB)

    Monty, J.P.; Lien, K.; Chong, M.S. [University of Melbourne, Department of Mechanical Engineering, Parkville, VIC (Australia); Allen, J.J. [New Mexico State University, Department of Mechanical Engineering, Las Cruces, NM (United States)

    2011-12-15

    A high Reynolds number boundary-layer wind-tunnel facility at New Mexico State University was fitted with a regularly distributed braille surface. The surface was such that braille dots were closely packed in the streamwise direction and sparsely spaced in the spanwise direction. This novel surface had an unexpected influence on the flow: the energy of the very large-scale features of wall turbulence (approximately six-times the boundary-layer thickness in length) became significantly attenuated, even into the logarithmic region. To the author's knowledge, this is the first experimental study to report a modification of 'superstructures' in a rough-wall turbulent boundary layer. The result gives rise to the possibility that flow control through very small, passive surface roughness may be possible at high Reynolds numbers, without the prohibitive drag penalty anticipated heretofore. Evidence was also found for the uninhibited existence of the near-wall cycle, well known to smooth-wall-turbulence researchers, in the spanwise space between roughness elements. (orig.)

  2. The relationship between the number of loci and the statistical support for the topology of UPGMA trees obtained from genetic distance data.

    Science.gov (United States)

    Highton, R

    1993-12-01

    An analysis of the relationship between the number of loci utilized in an electrophoretic study of genetic relationships and the statistical support for the topology of UPGMA trees is reported for two published data sets. These are Highton and Larson (Syst. Zool.28:579-599, 1979), an analysis of the relationships of 28 species of plethodonine salamanders, and Hedges (Syst. Zool., 35:1-21, 1986), a similar study of 30 taxa of Holarctic hylid frogs. As the number of loci increases, the statistical support for the topology at each node in UPGMA trees was determined by both the bootstrap and jackknife methods. The results show that the bootstrap and jackknife probabilities supporting the topology at some nodes of UPGMA trees increase as the number of loci utilized in a study is increased, as expected for nodes that have groupings that reflect phylogenetic relationships. The pattern of increase varies and is especially rapid in the case of groups with no close relatives. At nodes that likely do not represent correct phylogenetic relationships, the bootstrap probabilities do not increase and often decline with the addition of more loci.

  3. Implication of nonintegral occupation number and Fermi-Dirac statistics in the local-spin-density approximation applied to finite systems

    International Nuclear Information System (INIS)

    Dhar, S.

    1989-01-01

    In electronic-structure calculations for finite systems using the local-spin-density (LSD) approximation, it is assumed that the eigenvalues of the Kohn-Sham equation should obey Fermi-Dirac (FD) statistics. In order to comply with this assumption for some of the transition-metal atoms, a nonintegral occupation number is used which also minimizes the total energy. It is shown here that for finite systems it is not necessary that the eigenvalues of the Kohn-Sham equation obey FD statistics. It is also shown that the Kohn-Sham exchange potential used in all LSD models is correct only for integer occupation number. With a noninteger occupation number the LSD exchange potential will be smaller than that given by the Kohn-Sham potential. Ab initio self-consistent spin-polarized calculations have been performed numerically for the total energy of an iron atom. It is found that the ground state belongs to the 3d 6 4s 2 configuration. The ionization potentials of all the Fe/sup n/ + ions are reported and are in agreement with experiment

  4. Development and application of an optogenetic platform for controlling and imaging a large number of individual neurons

    Science.gov (United States)

    Mohammed, Ali Ibrahim Ali

    The understanding and treatment of brain disorders as well as the development of intelligent machines is hampered by the lack of knowledge of how the brain fundamentally functions. Over the past century, we have learned much about how individual neurons and neural networks behave, however new tools are critically needed to interrogate how neural networks give rise to complex brain processes and disease conditions. Recent innovations in molecular techniques, such as optogenetics, have enabled neuroscientists unprecedented precision to excite, inhibit and record defined neurons. The impressive sensitivity of currently available optogenetic sensors and actuators has now enabled the possibility of analyzing a large number of individual neurons in the brains of behaving animals. To promote the use of these optogenetic tools, this thesis integrates cutting edge optogenetic molecular sensors which is ultrasensitive for imaging neuronal activity with custom wide field optical microscope to analyze a large number of individual neurons in living brains. Wide-field microscopy provides a large field of view and better spatial resolution approaching the Abbe diffraction limit of fluorescent microscope. To demonstrate the advantages of this optical platform, we imaged a deep brain structure, the Hippocampus, and tracked hundreds of neurons over time while mouse was performing a memory task to investigate how those individual neurons related to behavior. In addition, we tested our optical platform in investigating transient neural network changes upon mechanical perturbation related to blast injuries. In this experiment, all blasted mice show a consistent change in neural network. A small portion of neurons showed a sustained calcium increase for an extended period of time, whereas the majority lost their activities. Finally, using optogenetic silencer to control selective motor cortex neurons, we examined their contributions to the network pathology of basal ganglia related to

  5. Sentinel node status prediction by four statistical models: results from a large bi-institutional series (n = 1132).

    Science.gov (United States)

    Mocellin, Simone; Thompson, John F; Pasquali, Sandro; Montesco, Maria C; Pilati, Pierluigi; Nitti, Donato; Saw, Robyn P; Scolyer, Richard A; Stretch, Jonathan R; Rossi, Carlo R

    2009-12-01

    To improve selection for sentinel node (SN) biopsy (SNB) in patients with cutaneous melanoma using statistical models predicting SN status. About 80% of patients currently undergoing SNB are node negative. In the absence of conclusive evidence of a SNBassociated survival benefit, these patients may be over-treated. Here, we tested the efficiency of 4 different models in predicting SN status. The clinicopathologic data (age, gender, tumor thickness, Clark level, regression, ulceration, histologic subtype, and mitotic index) of 1132 melanoma patients who had undergone SNB at institutions in Italy and Australia were analyzed. Logistic regression, classification tree, random forest, and support vector machine models were fitted to the data. The predictive models were built with the aim of maximizing the negative predictive value (NPV) and reducing the rate of SNB procedures though minimizing the error rate. After cross-validation logistic regression, classification tree, random forest, and support vector machine predictive models obtained clinically relevant NPV (93.6%, 94.0%, 97.1%, and 93.0%, respectively), SNB reduction (27.5%, 29.8%, 18.2%, and 30.1%, respectively), and error rates (1.8%, 1.8%, 0.5%, and 2.1%, respectively). Using commonly available clinicopathologic variables, predictive models can preoperatively identify a proportion of patients ( approximately 25%) who might be spared SNB, with an acceptable (1%-2%) error. If validated in large prospective series, these models might be implemented in the clinical setting for improved patient selection, which ultimately would lead to better quality of life for patients and optimization of resource allocation for the health care system.

  6. Global statistics of liquid water content and effective number concentration of water clouds over ocean derived from combined CALIPSO and MODIS measurements

    Directory of Open Access Journals (Sweden)

    Y. Hu

    2007-06-01

    Full Text Available This study presents an empirical relation that links the volume extinction coefficients of water clouds, the layer integrated depolarization ratios measured by lidar, and the effective radii of water clouds derived from collocated passive sensor observations. Based on Monte Carlo simulations of CALIPSO lidar observations, this method combines the cloud effective radius reported by MODIS with the lidar depolarization ratios measured by CALIPSO to estimate both the liquid water content and the effective number concentration of water clouds. The method is applied to collocated CALIPSO and MODIS measurements obtained during July and October of 2006, and January 2007. Global statistics of the cloud liquid water content and effective number concentration are presented.

  7. Relationship between accuracy and number of samples on statistical quantity and contour map of environmental gamma-ray dose rate. Example of random sampling

    International Nuclear Information System (INIS)

    Matsuda, Hideharu; Minato, Susumu

    2002-01-01

    The accuracy of statistical quantity like the mean value and contour map obtained by measurement of the environmental gamma-ray dose rate was evaluated by random sampling of 5 different model distribution maps made by the mean slope, -1.3, of power spectra calculated from the actually measured values. The values were derived from 58 natural gamma dose rate data reported worldwide ranging in the means of 10-100 Gy/h rates and 10 -3 -10 7 km 2 areas. The accuracy of the mean value was found around ±7% even for 60 or 80 samplings (the most frequent number) and the standard deviation had the accuracy less than 1/4-1/3 of the means. The correlation coefficient of the frequency distribution was found 0.860 or more for 200-400 samplings (the most frequent number) but of the contour map, 0.502-0.770. (K.H.)

  8. Individual differences influence two-digit number processing, but not their analog magnitude processing: a large-scale online study.

    Science.gov (United States)

    Huber, Stefan; Nuerk, Hans-Christoph; Reips, Ulf-Dietrich; Soltanlou, Mojtaba

    2017-12-23

    Symbolic magnitude comparison is one of the most well-studied cognitive processes in research on numerical cognition. However, while the cognitive mechanisms of symbolic magnitude processing have been intensively studied, previous studies have paid less attention to individual differences influencing symbolic magnitude comparison. Employing a two-digit number comparison task in an online setting, we replicated previous effects, including the distance effect, the unit-decade compatibility effect, and the effect of cognitive control on the adaptation to filler items, in a large-scale study in 452 adults. Additionally, we observed that the most influential individual differences were participants' first language, time spent playing computer games and gender, followed by reported alcohol consumption, age and mathematical ability. Participants who used a first language with a left-to-right reading/writing direction were faster than those who read and wrote in the right-to-left direction. Reported playing time for computer games was correlated with faster reaction times. Female participants showed slower reaction times and a larger unit-decade compatibility effect than male participants. Participants who reported never consuming alcohol showed overall slower response times than others. Older participants were slower, but more accurate. Finally, higher grades in mathematics were associated with faster reaction times. We conclude that typical experiments on numerical cognition that employ a keyboard as an input device can also be run in an online setting. Moreover, while individual differences have no influence on domain-specific magnitude processing-apart from age, which increases the decade distance effect-they generally influence performance on a two-digit number comparison task.

  9. Catering for large numbers of tourists: the McDonaldization of casual dining in Kruger National Park

    Directory of Open Access Journals (Sweden)

    Ferreira Sanette L.A.

    2016-09-01

    Full Text Available Since 2002 Kruger National Park (KNP has subjected to a commercialisation strategy. Regarding income generation, SANParks (1 sees KNP as the goose that lays the golden eggs. As part of SANParks’ commercialisation strategy and in response to providing services that are efficient, predictable and calculable for a large number of tourists, SANParks has allowed well-known branded restaurants to be established in certain rest camps in KNP. This innovation has raised a range of different concerns and opinions among the public. This paper investigates the what and the where of casual dining experiences in KNP; describes how the catering services have evolved over the last 70 years; and evaluates current visitor perceptions of the introduction of franchised restaurants in the park. The main research instrument was a questionnaire survey. Survey findings confirmed that restaurant managers, park managers and visitors recognise franchised restaurants as positive contributors to the unique KNP experience. Park managers appraised the franchised restaurants as mechanisms for funding conservation.

  10. Meta-ethnography 25 years on: challenges and insights for synthesising a large number of qualitative studies

    Science.gov (United States)

    2014-01-01

    Studies that systematically search for and synthesise qualitative research are becoming more evident in health care, and they can make an important contribution to patient care. Our team was funded to complete a meta-ethnography of patients’ experience of chronic musculoskeletal pain. It has been 25 years since Noblit and Hare published their core text on meta-ethnography, and the current health research environment brings additional challenges to researchers aiming to synthesise qualitative research. Noblit and Hare propose seven stages of meta-ethnography which take the researcher from formulating a research idea to expressing the findings. These stages are not discrete but form part of an iterative research process. We aimed to build on the methods of Noblit and Hare and explore the challenges of including a large number of qualitative studies into a qualitative systematic review. These challenges hinge upon epistemological and practical issues to be considered alongside expectations about what determines high quality research. This paper describes our method and explores these challenges. Central to our method was the process of collaborative interpretation of concepts and the decision to exclude original material where we could not decipher a concept. We use excerpts from our research team’s reflexive statements to illustrate the development of our methods. PMID:24951054

  11. Meta-ethnography 25 years on: challenges and insights for synthesising a large number of qualitative studies.

    Science.gov (United States)

    Toye, Francine; Seers, Kate; Allcock, Nick; Briggs, Michelle; Carr, Eloise; Barker, Karen

    2014-06-21

    Studies that systematically search for and synthesise qualitative research are becoming more evident in health care, and they can make an important contribution to patient care. Our team was funded to complete a meta-ethnography of patients' experience of chronic musculoskeletal pain. It has been 25 years since Noblit and Hare published their core text on meta-ethnography, and the current health research environment brings additional challenges to researchers aiming to synthesise qualitative research. Noblit and Hare propose seven stages of meta-ethnography which take the researcher from formulating a research idea to expressing the findings. These stages are not discrete but form part of an iterative research process. We aimed to build on the methods of Noblit and Hare and explore the challenges of including a large number of qualitative studies into a qualitative systematic review. These challenges hinge upon epistemological and practical issues to be considered alongside expectations about what determines high quality research. This paper describes our method and explores these challenges. Central to our method was the process of collaborative interpretation of concepts and the decision to exclude original material where we could not decipher a concept. We use excerpts from our research team's reflexive statements to illustrate the development of our methods.

  12. Attenuation of contaminant plumes in homogeneous aquifers: Sensitivity to source function at moderate to large peclet numbers

    International Nuclear Information System (INIS)

    Selander, W.N.; Lane, F.E.; Rowat, J.H.

    1995-05-01

    A groundwater mass transfer calculation is an essential part of the performance assessment for radioactive waste disposal facilities. AECL's IRUS (Intrusion Resistant Underground Structure) facility, which is designed for the near-surface disposal of low-level radioactive waste (LLRW), is to be situated in the sandy overburden at AECL's Chalk River Laboratories. Flow in the sandy aquifers at the proposed IRUS site is relatively homogeneous and advection-dominated (large Peclet numbers). Mass transfer along the mean direction of flow from the IRUS site may be described using the one-dimensional advection-dispersion equation, for which a Green's function representation of downstream radionuclide flux is convenient. This report shows that in advection-dominated aquifers, dispersive attenuation of initial contaminant releases depends principally on two time scales: the source duration and the pulse breakthrough time. Numerical investigation shows further that the maximum downstream flux or concentration depends on these time scales in a simple characteristic way that is minimally sensitive to the shape of the initial source pulse. (author). 11 refs., 2 tabs., 3 figs

  13. Large Eddy Simulation study of the development of finite-channel lock-release currents at high Grashof numbers

    Science.gov (United States)

    Ooi, Seng-Keat

    2005-11-01

    Lock-exchange gravity current flows produced by the instantaneous release of a heavy fluid are investigated using 3-D well resolved Large Eddy Simulation simulations at Grashof numbers up to 8*10^9. It is found the 3-D simulations correctly predict a constant front velocity over the initial slumping phase and a front speed decrease proportional to t-1/3 (the time t is measured from the release) over the inviscid phase, in agreement with theory. The evolution of the current in the simulations is found to be similar to that observed experimentally by Hacker et al. (1996). The effect of the dynamic LES model on the solutions is discussed. The energy budget of the current is discussed and the contribution of the turbulent dissipation to the total dissipation is analyzed. The limitations of less expensive 2D simulations are discussed; in particular their failure to correctly predict the spatio-temporal distributions of the bed shear stresses which is important in determining the amount of sediment the gravity current can entrain in the case in advances of a loose bed.

  14. Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa.

    Science.gov (United States)

    Yilmaz, Zeynep; Szatkiewicz, Jin P; Crowley, James J; Ancalade, NaEshia; Brandys, Marek K; van Elburg, Annemarie; de Kovel, Carolien G F; Adan, Roger A H; Hinney, Anke; Hebebrand, Johannes; Gratacos, Monica; Fernandez-Aranda, Fernando; Escaramis, Georgia; Gonzalez, Juan R; Estivill, Xavier; Zeggini, Eleftheria; Sullivan, Patrick F; Bulik, Cynthia M

    2017-08-01

    Anorexia nervosa (AN) is a serious and heritable psychiatric disorder. To date, studies of copy number variants (CNVs) have been limited and inconclusive because of small sample sizes. We conducted a case-only genome-wide CNV survey in 1983 female AN cases included in the Genetic Consortium for Anorexia Nervosa. Following stringent quality control procedures, we investigated whether pathogenic CNVs in regions previously implicated in psychiatric and neurodevelopmental disorders were present in AN cases. We observed two instances of the well-established pathogenic CNVs in AN cases. In addition, one case had a deletion in the 13q12 region, overlapping with a deletion reported previously in two AN cases. As a secondary aim, we also examined our sample for CNVs over 1 Mbp in size. Out of the 40 instances of such large CNVs that were not implicated previously for AN or neuropsychiatric phenotypes, two of them contained genes with previous neuropsychiatric associations, and only five of them had no associated reports in public CNV databases. Although ours is the largest study of its kind in AN, larger datasets are needed to comprehensively assess the role of CNVs in the etiology of AN.

  15. Retrieval of convective boundary layer wind field statistics from radar profiler measurements in conjunction with large eddy simulation

    Directory of Open Access Journals (Sweden)

    Danny Scipión

    2009-05-01

    Full Text Available The daytime convective boundary layer (CBL is characterized by strong turbulence that is primarily forced by buoyancy transport from the heated underlying surface. The present study focuses on an example of flow structure of the CBL as observed in the U.S. Great Plains on June 8, 2007. The considered CBL flow has been reproduced using a numerical large eddy simulation (LES, sampled with an LES-based virtual boundary layer radar (BLR, and probed with an actual operational radar profiler. The LES-generated CBL flow data are then ingested by the virtual BLR and treated as a proxy for prevailing atmospheric conditions. The mean flow and turbulence parameters retrieved via each technique (actual radar profiler, virtual BLR, and LES have been cross-analyzed and reasonable agreement was found between the CBL wind parameters obtained from the LES and those measured by the actual radar. Averaged vertical velocity variance estimates from the virtual and actual BLRs were compared with estimates calculated from the LES for different periods of time. There is good agreement in the estimates from all three sources. Also, values of the vertical velocity skewness retrieved by all three techniques have been inter-compared as a function of height for different stages of the CBL evolution, showing fair agreement with each other. All three retrievals contain positively skewed vertical velocity structure throughout the main portion of the CBL. Radar estimates of the turbulence kinetic energy (eddy dissipation rate (ε have been obtained based on the Doppler spectral width of the returned signal for the vertical radar beam. The radar estimates were averaged over time in the same fashion as the LES output data. The agreement between estimates was generally good, especially within the mixing layer. Discrepancies observed above the inversion layer may be explained by a weak turbulence signal in particular flow configurations. The virtual BLR produces voltage

  16. Email-Based Informed Consent: Innovative Method for Reaching Large Numbers of Subjects for Data Mining Research

    Science.gov (United States)

    Lee, Lesley R.; Mason, Sara S.; Babiak-Vazquez, Adriana; Ray, Stacie L.; Van Baalen, Mary

    2015-01-01

    Since the 2010 NASA authorization to make the Life Sciences Data Archive (LSDA) and Lifetime Surveillance of Astronaut Health (LSAH) data archives more accessible by the research and operational communities, demand for data has greatly increased. Correspondingly, both the number and scope of requests have increased, from 142 requests fulfilled in 2011 to 224 in 2014, and with some datasets comprising up to 1 million data points. To meet the demand, the LSAH and LSDA Repositories project was launched, which allows active and retired astronauts to authorize full, partial, or no access to their data for research without individual, study-specific informed consent. A one-on-one personal informed consent briefing is required to fully communicate the implications of the several tiers of consent. Due to the need for personal contact to conduct Repositories consent meetings, the rate of consenting has not kept up with demand for individualized, possibly attributable data. As a result, other methods had to be implemented to allow the release of large datasets, such as release of only de-identified data. However the compilation of large, de-identified data sets places a significant resource burden on LSAH and LSDA and may result in diminished scientific usefulness of the dataset. As a result, LSAH and LSDA worked with the JSC Institutional Review Board Chair, Astronaut Office physicians, and NASA Office of General Counsel personnel to develop a "Remote Consenting" process for retrospective data mining studies. This is particularly useful since the majority of the astronaut cohort is retired from the agency and living outside the Houston area. Originally planned as a method to send informed consent briefing slides and consent forms only by mail, Remote Consenting has evolved into a means to accept crewmember decisions on individual studies via their method of choice: email or paper copy by mail. To date, 100 emails have been sent to request participation in eight HRP

  17. Small on the Left, Large on the Right: Numbers Orient Visual Attention onto Space in Preverbal Infants

    Science.gov (United States)

    Bulf, Hermann; de Hevia, Maria Dolores; Macchi Cassia, Viola

    2016-01-01

    Numbers are represented as ordered magnitudes along a spatially oriented number line. While culture and formal education modulate the direction of this number-space mapping, it is a matter of debate whether its emergence is entirely driven by cultural experience. By registering 8-9-month-old infants' eye movements, this study shows that numerical…

  18. The application of the central limit theorem and the law of large numbers to facial soft tissue depths: T-Table robustness and trends since 2008.

    Science.gov (United States)

    Stephan, Carl N

    2014-03-01

    By pooling independent study means (x¯), the T-Tables use the central limit theorem and law of large numbers to average out study-specific sampling bias and instrument errors and, in turn, triangulate upon human population means (μ). Since their first publication in 2008, new data from >2660 adults have been collected (c.30% of the original sample) making a review of the T-Table's robustness timely. Updated grand means show that the new data have negligible impact on the previously published statistics: maximum change = 1.7 mm at gonion; and ≤1 mm at 93% of all landmarks measured. This confirms the utility of the 2008 T-Table as a proxy to soft tissue depth population means and, together with updated sample sizes (8851 individuals at pogonion), earmarks the 2013 T-Table as the premier mean facial soft tissue depth standard for craniofacial identification casework. The utility of the T-Table, in comparison with shorths and 75-shormaxes, is also discussed. © 2013 American Academy of Forensic Sciences.

  19. Statistical investigation on frequency, duration, number of X-ray investigations and radiation exposure to the patients of a district hospital on the outskirts of Munich

    Energy Technology Data Exchange (ETDEWEB)

    Nordmann, W

    1973-04-10

    Within the framework of a dissertation, X-ray examined patients were statistically surveyed during one month at the district hospital. The radiation exposure of the patients increased strongly particularly with men of the age of 21 to 30 and of 61 to 70. The causes are the multiply performed investigations after accidents as well as angiography at greater ages. The exposure is in the case of women particularly high between the ages of 66 and 70. In determining the gonadal exposure, the average values for the X-ray investigation at the time were referred to. The numbers give an approximate idea of to what extent single investigations with varying investigation or picture frequency can contribute to gonadal exposure.

  20. RANDOMNESS of Numbers DEFINITION(QUERY:WHAT? V HOW?) ONLY Via MAXWELL-BOLTZMANN CLASSICAL-Statistics(MBCS) Hot-Plasma VS. Digits-Clumping Log-Law NON-Randomness Inversion ONLY BOSE-EINSTEIN QUANTUM-Statistics(BEQS) .

    Science.gov (United States)

    Siegel, Z.; Siegel, Edward Carl-Ludwig

    2011-03-01

    RANDOMNESS of Numbers cognitive-semantics DEFINITION VIA Cognition QUERY: WHAT???, NOT HOW?) VS. computer-``science" mindLESS number-crunching (Harrel-Sipser-...) algorithmics Goldreich "PSEUDO-randomness"[Not.AMS(02)] mea-culpa is ONLY via MAXWELL-BOLTZMANN CLASSICAL-STATISTICS(NOT FDQS!!!) "hot-plasma" REPULSION VERSUS Newcomb(1881)-Weyl(1914;1916)-Benford(1938) "NeWBe" logarithmic-law digit-CLUMPING/ CLUSTERING NON-Randomness simple Siegel[AMS Joint.Mtg.(02)-Abs. # 973-60-124] algebraic-inversion to THE QUANTUM and ONLY BEQS preferentially SEQUENTIALLY lower-DIGITS CLUMPING/CLUSTERING with d = 0 BEC, is ONLY VIA Siegel-Baez FUZZYICS=CATEGORYICS (SON OF TRIZ)/"Category-Semantics"(C-S), latter intersection/union of Lawvere(1964)-Siegel(1964)] category-theory (matrix: MORPHISMS V FUNCTORS) "+" cognitive-semantics'' (matrix: ANTONYMS V SYNONYMS) yields Siegel-Baez FUZZYICS=CATEGORYICS/C-S tabular list-format matrix truth-table analytics: MBCS RANDOMNESS TRUTH/EMET!!!

  1. Childhood Cancer Statistics

    Science.gov (United States)

    ... Watchdog Ratings Feedback Contact Select Page Childhood Cancer Statistics Home > Cancer Resources > Childhood Cancer Statistics Childhood Cancer Statistics – Graphs and Infographics Number of Diagnoses Incidence Rates ...

  2. Analyzing large gene expression and methylation data profiles using StatBicRM: statistical biclustering-based rule mining.

    Directory of Open Access Journals (Sweden)

    Ujjwal Maulik

    Full Text Available Microarray and beadchip are two most efficient techniques for measuring gene expression and methylation data in bioinformatics. Biclustering deals with the simultaneous clustering of genes and samples. In this article, we propose a computational rule mining framework, StatBicRM (i.e., statistical biclustering-based rule mining to identify special type of rules and potential biomarkers using integrated approaches of statistical and binary inclusion-maximal biclustering techniques from the biological datasets. At first, a novel statistical strategy has been utilized to eliminate the insignificant/low-significant/redundant genes in such way that significance level must satisfy the data distribution property (viz., either normal distribution or non-normal distribution. The data is then discretized and post-discretized, consecutively. Thereafter, the biclustering technique is applied to identify maximal frequent closed homogeneous itemsets. Corresponding special type of rules are then extracted from the selected itemsets. Our proposed rule mining method performs better than the other rule mining algorithms as it generates maximal frequent closed homogeneous itemsets instead of frequent itemsets. Thus, it saves elapsed time, and can work on big dataset. Pathway and Gene Ontology analyses are conducted on the genes of the evolved rules using David database. Frequency analysis of the genes appearing in the evolved rules is performed to determine potential biomarkers. Furthermore, we also classify the data to know how much the evolved rules are able to describe accurately the remaining test (unknown data. Subsequently, we also compare the average classification accuracy, and other related factors with other rule-based classifiers. Statistical significance tests are also performed for verifying the statistical relevance of the comparative results. Here, each of the other rule mining methods or rule-based classifiers is also starting with the same post

  3. Analyzing large gene expression and methylation data profiles using StatBicRM: statistical biclustering-based rule mining.

    Science.gov (United States)

    Maulik, Ujjwal; Mallik, Saurav; Mukhopadhyay, Anirban; Bandyopadhyay, Sanghamitra

    2015-01-01

    Microarray and beadchip are two most efficient techniques for measuring gene expression and methylation data in bioinformatics. Biclustering deals with the simultaneous clustering of genes and samples. In this article, we propose a computational rule mining framework, StatBicRM (i.e., statistical biclustering-based rule mining) to identify special type of rules and potential biomarkers using integrated approaches of statistical and binary inclusion-maximal biclustering techniques from the biological datasets. At first, a novel statistical strategy has been utilized to eliminate the insignificant/low-significant/redundant genes in such way that significance level must satisfy the data distribution property (viz., either normal distribution or non-normal distribution). The data is then discretized and post-discretized, consecutively. Thereafter, the biclustering technique is applied to identify maximal frequent closed homogeneous itemsets. Corresponding special type of rules are then extracted from the selected itemsets. Our proposed rule mining method performs better than the other rule mining algorithms as it generates maximal frequent closed homogeneous itemsets instead of frequent itemsets. Thus, it saves elapsed time, and can work on big dataset. Pathway and Gene Ontology analyses are conducted on the genes of the evolved rules using David database. Frequency analysis of the genes appearing in the evolved rules is performed to determine potential biomarkers. Furthermore, we also classify the data to know how much the evolved rules are able to describe accurately the remaining test (unknown) data. Subsequently, we also compare the average classification accuracy, and other related factors with other rule-based classifiers. Statistical significance tests are also performed for verifying the statistical relevance of the comparative results. Here, each of the other rule mining methods or rule-based classifiers is also starting with the same post-discretized data

  4. Retrieval of very large numbers of items in the Web of Science: an exercise to develop accurate search strategies

    NARCIS (Netherlands)

    Arencibia-Jorge, R.; Leydesdorff, L.; Chinchilla-Rodríguez, Z.; Rousseau, R.; Paris, S.W.

    2009-01-01

    The Web of Science interface counts at most 100,000 retrieved items from a single query. If the query results in a dataset containing more than 100,000 items the number of retrieved items is indicated as >100,000. The problem studied here is how to find the exact number of items in a query that

  5. An analysis of a large dataset on immigrant integration in Spain. The Statistical Mechanics perspective on Social Action

    Science.gov (United States)

    Barra, Adriano; Contucci, Pierluigi; Sandell, Rickard; Vernia, Cecilia

    2014-02-01

    How does immigrant integration in a country change with immigration density? Guided by a statistical mechanics perspective we propose a novel approach to this problem. The analysis focuses on classical integration quantifiers such as the percentage of jobs (temporary and permanent) given to immigrants, mixed marriages, and newborns with parents of mixed origin. We find that the average values of different quantifiers may exhibit either linear or non-linear growth on immigrant density and we suggest that social action, a concept identified by Max Weber, causes the observed non-linearity. Using the statistical mechanics notion of interaction to quantitatively emulate social action, a unified mathematical model for integration is proposed and it is shown to explain both growth behaviors observed. The linear theory instead, ignoring the possibility of interaction effects would underestimate the quantifiers up to 30% when immigrant densities are low, and overestimate them as much when densities are high. The capacity to quantitatively isolate different types of integration mechanisms makes our framework a suitable tool in the quest for more efficient integration policies.

  6. Experimental observation of pulsating instability under acoustic field in downward-propagating flames at large Lewis number

    KAUST Repository

    Yoon, Sung Hwan

    2017-10-12

    According to previous theory, pulsating propagation in a premixed flame only appears when the reduced Lewis number, β(Le-1), is larger than a critical value (Sivashinsky criterion: 4(1 +3) ≈ 11), where β represents the Zel\\'dovich number (for general premixed flames, β ≈ 10), which requires Lewis number Le > 2.1. However, few experimental observation have been reported because the critical reduced Lewis number for the onset of pulsating instability is beyond what can be reached in experiments. Furthermore, the coupling with the unavoidable hydrodynamic instability limits the observation of pure pulsating instabilities in flames. Here, we describe a novel method to observe the pulsating instability. We utilize a thermoacoustic field caused by interaction between heat release and acoustic pressure fluctuations of the downward-propagating premixed flames in a tube to enhance conductive heat loss at the tube wall and radiative heat loss at the open end of the tube due to extended flame residence time by diminished flame surface area, i.e., flat flame. The thermoacoustic field allowed pure observation of the pulsating motion since the primary acoustic force suppressed the intrinsic hydrodynamic instability resulting from thermal expansion. By employing this method, we have provided new experimental observations of the pulsating instability for premixed flames. The Lewis number (i.e., Le ≈ 1.86) was less than the critical value suggested previously.

  7. Basics of statistical physics

    CERN Document Server

    Müller-Kirsten, Harald J W

    2013-01-01

    Statistics links microscopic and macroscopic phenomena, and requires for this reason a large number of microscopic elements like atoms. The results are values of maximum probability or of averaging. This introduction to statistical physics concentrates on the basic principles, and attempts to explain these in simple terms supplemented by numerous examples. These basic principles include the difference between classical and quantum statistics, a priori probabilities as related to degeneracies, the vital aspect of indistinguishability as compared with distinguishability in classical physics, the differences between conserved and non-conserved elements, the different ways of counting arrangements in the three statistics (Maxwell-Boltzmann, Fermi-Dirac, Bose-Einstein), the difference between maximization of the number of arrangements of elements, and averaging in the Darwin-Fowler method. Significant applications to solids, radiation and electrons in metals are treated in separate chapters, as well as Bose-Eins...

  8. Image Statistics

    Energy Technology Data Exchange (ETDEWEB)

    Wendelberger, Laura Jean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-08

    In large datasets, it is time consuming or even impossible to pick out interesting images. Our proposed solution is to find statistics to quantify the information in each image and use those to identify and pick out images of interest.

  9. Does Decision Quality (Always) Increase with the Size of Information Samples? Some Vicissitudes in Applying the Law of Large Numbers

    Science.gov (United States)

    Fiedler, Klaus; Kareev, Yaakov

    2006-01-01

    Adaptive decision making requires that contingencies between decision options and their relative assets be assessed accurately and quickly. The present research addresses the challenging notion that contingencies may be more visible from small than from large samples of observations. An algorithmic account for such a seemingly paradoxical effect…

  10. The Limits and Possibilities of International Large-Scale Assessments. Education Policy Brief. Volume 9, Number 2, Spring 2011

    Science.gov (United States)

    Rutkowski, David J.; Prusinski, Ellen L.

    2011-01-01

    The staff of the Center for Evaluation & Education Policy (CEEP) at Indiana University is often asked about how international large-scale assessments influence U.S. educational policy. This policy brief is designed to provide answers to some of the most frequently asked questions encountered by CEEP researchers concerning the three most popular…

  11. Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa

    NARCIS (Netherlands)

    Yilmaz, Zeynep; Szatkiewicz, Jin P; Crowley, James J; Ancalade, NaEshia; Brandys, Marek K; van Elburg, Annemarie; de Kovel, Carolien G F; Adan, Roger A H; Hinney, Anke; Hebebrand, Johannes; Gratacos, Monica; Fernandez-Aranda, Fernando; Escaramis, Georgia; Gonzalez, Juan R; Estivill, Xavier; Zeggini, Eleftheria; Sullivan, Patrick F; Bulik, Cynthia M; Genetic Consortium for Anorexia Nervosa, Wellcome Trust Case Control Consortium 3

    Anorexia nervosa (AN) is a serious and heritable psychiatric disorder. To date, studies of copy number variants (CNVs) have been limited and inconclusive because of small sample sizes. We conducted a case-only genome-wide CNV survey in 1983 female AN cases included in the Genetic Consortium for

  12. Investigation into impacts of large numbers of visitors on the collection environment at Our Lord in the Attic

    NARCIS (Netherlands)

    Maekawa, S.; Ankersmit, Bart; Neuhaus, E.; Schellen, H.L.; Beltran, V.; Boersma, F.; Padfield, T.; Borchersen, K.

    2007-01-01

    Our Lord in the Attic is a historic house museum located in the historic center of Amsterdam, The Netherlands. It is a typical 17th century Dutch canal house, with a hidden Church in the attic. The Church was used regularly until 1887 when the house became a museum. The annual total number of

  13. A Few Large Roads or Many Small Ones? How to Accommodate Growth in Vehicle Numbers to Minimise Impacts on Wildlife

    Science.gov (United States)

    Rhodes, Jonathan R.; Lunney, Daniel; Callaghan, John; McAlpine, Clive A.

    2014-01-01

    Roads and vehicular traffic are among the most pervasive of threats to biodiversity because they fragmenting habitat, increasing mortality and opening up new areas for the exploitation of natural resources. However, the number of vehicles on roads is increasing rapidly and this is likely to continue into the future, putting increased pressure on wildlife populations. Consequently, a major challenge is the planning of road networks to accommodate increased numbers of vehicles, while minimising impacts on wildlife. Nonetheless, we currently have few principles for guiding decisions on road network planning to reduce impacts on wildlife in real landscapes. We addressed this issue by developing an approach for quantifying the impact on wildlife mortality of two alternative mechanisms for accommodating growth in vehicle numbers: (1) increasing the number of roads, and (2) increasing traffic volumes on existing roads. We applied this approach to a koala (Phascolarctos cinereus) population in eastern Australia and quantified the relative impact of each strategy on mortality. We show that, in most cases, accommodating growth in traffic through increases in volumes on existing roads has a lower impact than building new roads. An exception is where the existing road network has very low road density, but very high traffic volumes on each road. These findings have important implications for how we design road networks to reduce their impacts on biodiversity. PMID:24646891

  14. A few large roads or many small ones? How to accommodate growth in vehicle numbers to minimise impacts on wildlife.

    Directory of Open Access Journals (Sweden)

    Jonathan R Rhodes

    Full Text Available Roads and vehicular traffic are among the most pervasive of threats to biodiversity because they fragmenting habitat, increasing mortality and opening up new areas for the exploitation of natural resources. However, the number of vehicles on roads is increasing rapidly and this is likely to continue into the future, putting increased pressure on wildlife populations. Consequently, a major challenge is the planning of road networks to accommodate increased numbers of vehicles, while minimising impacts on wildlife. Nonetheless, we currently have few principles for guiding decisions on road network planning to reduce impacts on wildlife in real landscapes. We addressed this issue by developing an approach for quantifying the impact on wildlife mortality of two alternative mechanisms for accommodating growth in vehicle numbers: (1 increasing the number of roads, and (2 increasing traffic volumes on existing roads. We applied this approach to a koala (Phascolarctos cinereus population in eastern Australia and quantified the relative impact of each strategy on mortality. We show that, in most cases, accommodating growth in traffic through increases in volumes on existing roads has a lower impact than building new roads. An exception is where the existing road network has very low road density, but very high traffic volumes on each road. These findings have important implications for how we design road networks to reduce their impacts on biodiversity.

  15. A few large roads or many small ones? How to accommodate growth in vehicle numbers to minimise impacts on wildlife.

    Science.gov (United States)

    Rhodes, Jonathan R; Lunney, Daniel; Callaghan, John; McAlpine, Clive A

    2014-01-01

    Roads and vehicular traffic are among the most pervasive of threats to biodiversity because they fragmenting habitat, increasing mortality and opening up new areas for the exploitation of natural resources. However, the number of vehicles on roads is increasing rapidly and this is likely to continue into the future, putting increased pressure on wildlife populations. Consequently, a major challenge is the planning of road networks to accommodate increased numbers of vehicles, while minimising impacts on wildlife. Nonetheless, we currently have few principles for guiding decisions on road network planning to reduce impacts on wildlife in real landscapes. We addressed this issue by developing an approach for quantifying the impact on wildlife mortality of two alternative mechanisms for accommodating growth in vehicle numbers: (1) increasing the number of roads, and (2) increasing traffic volumes on existing roads. We applied this approach to a koala (Phascolarctos cinereus) population in eastern Australia and quantified the relative impact of each strategy on mortality. We show that, in most cases, accommodating growth in traffic through increases in volumes on existing roads has a lower impact than building new roads. An exception is where the existing road network has very low road density, but very high traffic volumes on each road. These findings have important implications for how we design road networks to reduce their impacts on biodiversity.

  16. Small genomes and large seeds: chromosome numbers, genome size and seed mass in diploid Aesculus species (Sapindaceae)

    Czech Academy of Sciences Publication Activity Database

    Krahulcová, Anna; Trávníček, Pavel; Krahulec, František; Rejmánek, M.

    2017-01-01

    Roč. 119, č. 6 (2017), s. 957-964 ISSN 0305-7364 Institutional support: RVO:67985939 Keywords : Aesculus * chromosome number * genome size * phylogeny * seed mass Subject RIV: EF - Botanics OBOR OECD: Plant sciences, botany Impact factor: 4.041, year: 2016

  17. Structures and algorithms for post-processing large data sets and multi-variate functions in spatio-temporal statistics

    KAUST Repository

    Litvinenko, Alexander

    2017-12-10

    Matrices began in the 2nd century BC with the Chinese. One can find traces, which go to the 4th century BC to the Babylonians. The text ``Nine Chapters of the Mathematical Art\\'\\' written during the Han Dynasty in China gave the first known example of matrix methods. They were used to solve simultaneous linear equations (more in http://math.nie.edu.sg/bwjyeo/it/MathsOnline_AM/livemath/the/IT3AMMatricesHistory.html). The first ideas of the maximum likelihood estimation (MLE) was introduces by Laplace (1749-1827), by Gauss (1777-1855), the Likelihood was defined by Thiele Thorvald (1838-1910). Why we still use matrices? The matrix data format is more than 2200 years old. Our world is multi-dimensional! Why not to introduce a more appropriate data format and why not to reformulate the MLE method for it? In this work we are utilizing the low-rank tensor formats for multi-dimansional functions, which appear in spatial statistics.

  18. Algorithm for computing significance levels using the Kolmogorov-Smirnov statistic and valid for both large and small samples

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, S.E.; Fields, D.E.

    1983-10-01

    The KSTEST code presented here is designed to perform the Kolmogorov-Smirnov one-sample test. The code may be used as a stand-alone program or the principal subroutines may be excerpted and used to service other programs. The Kolmogorov-Smirnov one-sample test is a nonparametric goodness-of-fit test. A number of codes to perform this test are in existence, but they suffer from the inability to provide meaningful results in the case of small sample sizes (number of values less than or equal to 80). The KSTEST code overcomes this inadequacy by using two distinct algorithms. If the sample size is greater than 80, an asymptotic series developed by Smirnov is evaluated. If the sample size is 80 or less, a table of values generated by Birnbaum is referenced. Valid results can be obtained from KSTEST when the sample contains from 3 to 300 data points. The program was developed on a Digital Equipment Corporation PDP-10 computer using the FORTRAN-10 language. The code size is approximately 450 card images and the typical CPU execution time is 0.19 s.

  19. CAN'T MISS--conquer any number task by making important statistics simple. Part 2. Probability, populations, samples, and normal distributions.

    Science.gov (United States)

    Hansen, John P

    2003-01-01

    Healthcare quality improvement professionals need to understand and use inferential statistics to interpret sample data from their organizations. In quality improvement and healthcare research studies all the data from a population often are not available, so investigators take samples and make inferences about the population by using inferential statistics. This three-part series will give readers an understanding of the concepts of inferential statistics as well as the specific tools for calculating confidence intervals for samples of data. This article, Part 2, describes probability, populations, and samples. The uses of descriptive and inferential statistics are outlined. The article also discusses the properties and probability of normal distributions, including the standard normal distribution.

  20. Precise large deviations of aggregate claims in a size-dependent renewal risk model with stopping time claim-number process

    Directory of Open Access Journals (Sweden)

    Shuo Zhang

    2017-04-01

    Full Text Available Abstract In this paper, we consider a size-dependent renewal risk model with stopping time claim-number process. In this model, we do not make any assumption on the dependence structure of claim sizes and inter-arrival times. We study large deviations of the aggregate amount of claims. For the subexponential heavy-tailed case, we obtain a precise large-deviation formula; our method substantially relies on a martingale for the structure of our models.

  1. Hungarian Marfan family with large FBN1 deletion calls attention to copy number variation detection in the current NGS era

    Science.gov (United States)

    Ágg, Bence; Meienberg, Janine; Kopps, Anna M.; Fattorini, Nathalie; Stengl, Roland; Daradics, Noémi; Pólos, Miklós; Bors, András; Radovits, Tamás; Merkely, Béla; De Backer, Julie; Szabolcs, Zoltán; Mátyás, Gábor

    2018-01-01

    Copy number variations (CNVs) comprise about 10% of reported disease-causing mutations in Mendelian disorders. Nevertheless, pathogenic CNVs may have been under-detected due to the lack or insufficient use of appropriate detection methods. In this report, on the example of the diagnostic odyssey of a patient with Marfan syndrome (MFS) harboring a hitherto unreported 32-kb FBN1 deletion, we highlight the need for and the feasibility of testing for CNVs (>1 kb) in Mendelian disorders in the current next-generation sequencing (NGS) era. PMID:29850152

  2. Numerical simulation of nonstationary dissipative structures in 3D double-diffusive convection at large Rayleigh numbers

    Science.gov (United States)

    Kozitskiy, Sergey

    2018-05-01

    Numerical simulation of nonstationary dissipative structures in 3D double-diffusive convection has been performed by using the previously derived system of complex Ginzburg-Landau type amplitude equations, valid in a neighborhood of Hopf bifurcation points. Simulation has shown that the state of spatiotemporal chaos develops in the system. It has the form of nonstationary structures that depend on the parameters of the system. The shape of structures does not depend on the initial conditions, and a limited number of spectral components participate in their formation.

  3. Simulation of droplet impact onto a deep pool for large Froude numbers in different open-source codes

    Science.gov (United States)

    Korchagova, V. N.; Kraposhin, M. V.; Marchevsky, I. K.; Smirnova, E. V.

    2017-11-01

    A droplet impact on a deep pool can induce macro-scale or micro-scale effects like a crown splash, a high-speed jet, formation of secondary droplets or thin liquid films, etc. It depends on the diameter and velocity of the droplet, liquid properties, effects of external forces and other factors that a ratio of dimensionless criteria can account for. In the present research, we considered the droplet and the pool consist of the same viscous incompressible liquid. We took surface tension into account but neglected gravity forces. We used two open-source codes (OpenFOAM and Gerris) for our computations. We review the possibility of using these codes for simulation of processes in free-surface flows that may take place after a droplet impact on the pool. Both codes simulated several modes of droplet impact. We estimated the effect of liquid properties with respect to the Reynolds number and Weber number. Numerical simulation enabled us to find boundaries between different modes of droplet impact on a deep pool and to plot corresponding mode maps. The ratio of liquid density to that of the surrounding gas induces several changes in mode maps. Increasing this density ratio suppresses the crown splash.

  4. In-Depth Investigation of Statistical and Physicochemical Properties on the Field Study of the Intermittent Filling of Large Water Tanks

    Directory of Open Access Journals (Sweden)

    Do-Hwan Kim

    2017-01-01

    Full Text Available Large-demand customers, generally high-density dwellings and buildings, have dedicated ground or elevated water tanks to consistently supply drinking water to residents. Online field measurement for Nonsan-2 district meter area demonstrated that intermittent replenishment from large-demand customers could disrupt the normal operation of a water distribution system by taking large quantities of water in short times when filling the tanks from distribution mains. Based on the previous results of field measurement for hydraulic and water quality parameters, statistical analysis is performed for measured data in terms of autocorrelation, power spectral density, and cross-correlation. The statistical results show that the intermittent filling interval of 6.7 h and diurnal demand pattern of 23.3 h are detected through autocorrelation analyses, the similarities of the flow-pressure and the turbidity-particle count data are confirmed as a function of frequency through power spectral density analyses, and a strong cross-correlation is observed in the flow-pressure and turbidity-particle count analyses. In addition, physicochemical results show that the intermittent refill of storage tank from large-demand customers induces abnormal flow and pressure fluctuations and results in transient-induced turbid flow mainly composed of fine particles ranging within 2–4 μm and constituting Fe, Si, and Al.

  5. Reducing the memory size in the study of statistical properties of the pseudo-random number generators, focused on solving problems of cryptographic information protection

    International Nuclear Information System (INIS)

    Chugunkov, I.V.

    2014-01-01

    The report contains the description of an approach based on calculation of missing sets quantity, which allows to reduce memory usage needed for implementation of statistical tests. Information about estimation procedure of test statistics derived as a result of using this approach is also provided [ru

  6. Digest of Education Statistics, 2011. NCES 2012-001 [Appendix A: Guide to Sources; Appendix B: Definitions; Appendix C: Index of Table Numbers

    Science.gov (United States)

    Snyder, Thomas D.; Dillow, Sally A.

    2012-01-01

    The 2011 edition of the "Digest of Education Statistics" is the 47th in a series of publications initiated in 1962. The "Digest" has been issued annually except for combined editions for the years 1977-78, 1983-84, and 1985-86. Its primary purpose is to provide a compilation of statistical information covering the broad field…

  7. Digest of Education Statistics, 2012. NCES 2014-015 [Appendix A: Guide to Sources; Appendix B: Definitions; Appendix C: Index of Table Numbers

    Science.gov (United States)

    Snyder, Thomas D.; Dillow, Sally A.

    2013-01-01

    The 2012 edition of the "Digest of Education Statistics" is the 48th in a series of publications initiated in 1962. The "Digest" has been issued annually except for combined editions for the years 1977-78, 1983-84, and 1985-86. Its primary purpose is to provide a compilation of statistical information covering the broad field…

  8. TO BE OR NOT TO BE: AN INFORMATIVE NON-SYMBOLIC NUMERICAL MAGNITUDE PROCESSING STUDY ABOUT SMALL VERSUS LARGE NUMBERS IN INFANTS

    Directory of Open Access Journals (Sweden)

    Annelies CEULEMANS

    2014-03-01

    Full Text Available Many studies tested the association between numerical magnitude processing and mathematical achievement with conflicting findings reported for individuals with mathematical learning disorders. Some of the inconsistencies might be explained by the number of non-symbolic stimuli or dot collections used in studies. It has been hypothesized that there is an object-file system for ‘small’ and an analogue magnitude system for ‘large’ numbers. This two-system account has been supported by the set size limit of the object-file system (three items. A boundary was defined, accordingly, categorizing numbers below four as ‘small’ and from four and above as ‘large’. However, data on ‘small’ number processing and on the ‘boundary’ between small and large numbers are missing. In this contribution we provide data from infants discriminating between the number sets 4 vs. 8 and 1 vs. 4, both containing the number four combined with a small and a large number respectively. Participants were 25 and 26 full term 9-month-olds for 4 vs. 8 and 1 vs. 4 respectively. The stimuli (dots were controlled for continuous variables. Eye-tracking was combined with the habituation paradigm. The results showed that the infants were successful in discriminating 1 from 4, but failed to discriminate 4 from 8 dots. This finding supports the assumption of the number four as a ‘small’ number and enlarges the object-file system’s limit. This study might help to explain inconsistencies in studies. Moreover, the information may be useful in answering parent’s questions about challenges that vulnerable children with number processing problems, such as children with mathematical learning disorders, might encounter. In addition, the study might give some information on the stimuli that can be used to effectively foster children’s magnitude processing skills.

  9. Genomic selection and association mapping in rice (Oryza sativa): effect of trait genetic architecture, training population composition, marker number and statistical model on accuracy of rice genomic selection in elite, tropical rice breeding lines.

    Science.gov (United States)

    Spindel, Jennifer; Begum, Hasina; Akdemir, Deniz; Virk, Parminder; Collard, Bertrand; Redoña, Edilberto; Atlin, Gary; Jannink, Jean-Luc; McCouch, Susan R

    2015-02-01

    Genomic Selection (GS) is a new breeding method in which genome-wide markers are used to predict the breeding value of individuals in a breeding population. GS has been shown to improve breeding efficiency in dairy cattle and several crop plant species, and here we evaluate for the first time its efficacy for breeding inbred lines of rice. We performed a genome-wide association study (GWAS) in conjunction with five-fold GS cross-validation on a population of 363 elite breeding lines from the International Rice Research Institute's (IRRI) irrigated rice breeding program and herein report the GS results. The population was genotyped with 73,147 markers using genotyping-by-sequencing. The training population, statistical method used to build the GS model, number of markers, and trait were varied to determine their effect on prediction accuracy. For all three traits, genomic prediction models outperformed prediction based on pedigree records alone. Prediction accuracies ranged from 0.31 and 0.34 for grain yield and plant height to 0.63 for flowering time. Analyses using subsets of the full marker set suggest that using one marker every 0.2 cM is sufficient for genomic selection in this collection of rice breeding materials. RR-BLUP was the best performing statistical method for grain yield where no large effect QTL were detected by GWAS, while for flowering time, where a single very large effect QTL was detected, the non-GS multiple linear regression method outperformed GS models. For plant height, in which four mid-sized QTL were identified by GWAS, random forest produced the most consistently accurate GS models. Our results suggest that GS, informed by GWAS interpretations of genetic architecture and population structure, could become an effective tool for increasing the efficiency of rice breeding as the costs of genotyping continue to decline.

  10. Genomic selection and association mapping in rice (Oryza sativa: effect of trait genetic architecture, training population composition, marker number and statistical model on accuracy of rice genomic selection in elite, tropical rice breeding lines.

    Directory of Open Access Journals (Sweden)

    Jennifer Spindel

    2015-02-01

    Full Text Available Genomic Selection (GS is a new breeding method in which genome-wide markers are used to predict the breeding value of individuals in a breeding population. GS has been shown to improve breeding efficiency in dairy cattle and several crop plant species, and here we evaluate for the first time its efficacy for breeding inbred lines of rice. We performed a genome-wide association study (GWAS in conjunction with five-fold GS cross-validation on a population of 363 elite breeding lines from the International Rice Research Institute's (IRRI irrigated rice breeding program and herein report the GS results. The population was genotyped with 73,147 markers using genotyping-by-sequencing. The training population, statistical method used to build the GS model, number of markers, and trait were varied to determine their effect on prediction accuracy. For all three traits, genomic prediction models outperformed prediction based on pedigree records alone. Prediction accuracies ranged from 0.31 and 0.34 for grain yield and plant height to 0.63 for flowering time. Analyses using subsets of the full marker set suggest that using one marker every 0.2 cM is sufficient for genomic selection in this collection of rice breeding materials. RR-BLUP was the best performing statistical method for grain yield where no large effect QTL were detected by GWAS, while for flowering time, where a single very large effect QTL was detected, the non-GS multiple linear regression method outperformed GS models. For plant height, in which four mid-sized QTL were identified by GWAS, random forest produced the most consistently accurate GS models. Our results suggest that GS, informed by GWAS interpretations of genetic architecture and population structure, could become an effective tool for increasing the efficiency of rice breeding as the costs of genotyping continue to decline.

  11. Genomic Selection and Association Mapping in Rice (Oryza sativa): Effect of Trait Genetic Architecture, Training Population Composition, Marker Number and Statistical Model on Accuracy of Rice Genomic Selection in Elite, Tropical Rice Breeding Lines

    Science.gov (United States)

    Spindel, Jennifer; Begum, Hasina; Akdemir, Deniz; Virk, Parminder; Collard, Bertrand; Redoña, Edilberto; Atlin, Gary; Jannink, Jean-Luc; McCouch, Susan R.

    2015-01-01

    Genomic Selection (GS) is a new breeding method in which genome-wide markers are used to predict the breeding value of individuals in a breeding population. GS has been shown to improve breeding efficiency in dairy cattle and several crop plant species, and here we evaluate for the first time its efficacy for breeding inbred lines of rice. We performed a genome-wide association study (GWAS) in conjunction with five-fold GS cross-validation on a population of 363 elite breeding lines from the International Rice Research Institute's (IRRI) irrigated rice breeding program and herein report the GS results. The population was genotyped with 73,147 markers using genotyping-by-sequencing. The training population, statistical method used to build the GS model, number of markers, and trait were varied to determine their effect on prediction accuracy. For all three traits, genomic prediction models outperformed prediction based on pedigree records alone. Prediction accuracies ranged from 0.31 and 0.34 for grain yield and plant height to 0.63 for flowering time. Analyses using subsets of the full marker set suggest that using one marker every 0.2 cM is sufficient for genomic selection in this collection of rice breeding materials. RR-BLUP was the best performing statistical method for grain yield where no large effect QTL were detected by GWAS, while for flowering time, where a single very large effect QTL was detected, the non-GS multiple linear regression method outperformed GS models. For plant height, in which four mid-sized QTL were identified by GWAS, random forest produced the most consistently accurate GS models. Our results suggest that GS, informed by GWAS interpretations of genetic architecture and population structure, could become an effective tool for increasing the efficiency of rice breeding as the costs of genotyping continue to decline. PMID:25689273

  12. Method for the radioimmunoassay of large numbers of samples using quantitative autoradiography of multiple-well plates

    International Nuclear Information System (INIS)

    Luner, S.J.

    1978-01-01

    A double antibody assay for thyroxine using 125 I as label was carried out on 10-μl samples in Microtiter V-plates. After an additional centrifugation to compact the precipitates the plates were placed in contact with x-ray film overnight and the spots were scanned. In the 20 to 160 ng/ml range the average coefficient of variation for thyroxine concentration determined on the basis of film spot optical density was 11 percent compared to 4.8 percent obtained using a standard gamma counter. Eliminating the need for each sample to spend on the order of 1 min in a crystal well detector makes the method convenient for large-scale applications involving more than 3000 samples per day

  13. How to implement a quantum algorithm on a large number of qubits by controlling one central qubit

    Science.gov (United States)

    Zagoskin, Alexander; Ashhab, Sahel; Johansson, J. R.; Nori, Franco

    2010-03-01

    It is desirable to minimize the number of control parameters needed to perform a quantum algorithm. We show that, under certain conditions, an entire quantum algorithm can be efficiently implemented by controlling a single central qubit in a quantum computer. We also show that the different system parameters do not need to be designed accurately during fabrication. They can be determined through the response of the central qubit to external driving. Our proposal is well suited for hybrid architectures that combine microscopic and macroscopic qubits. More details can be found in: A.M. Zagoskin, S. Ashhab, J.R. Johansson, F. Nori, Quantum two-level systems in Josephson junctions as naturally formed qubits, Phys. Rev. Lett. 97, 077001 (2006); and S. Ashhab, J.R. Johansson, F. Nori, Rabi oscillations in a qubit coupled to a quantum two-level system, New J. Phys. 8, 103 (2006).

  14. DISCOVERY OF A LARGE NUMBER OF CANDIDATE PROTOCLUSTERS TRACED BY ∼15 Mpc-SCALE GALAXY OVERDENSITIES IN COSMOS

    International Nuclear Information System (INIS)

    Chiang, Yi-Kuan; Gebhardt, Karl; Overzier, Roderik

    2014-01-01

    To demonstrate the feasibility of studying the epoch of massive galaxy cluster formation in a more systematic manner using current and future galaxy surveys, we report the discovery of a large sample of protocluster candidates in the 1.62 deg 2 COSMOS/UltraVISTA field traced by optical/infrared selected galaxies using photometric redshifts. By comparing properly smoothed three-dimensional galaxy density maps of the observations and a set of matched simulations incorporating the dominant observational effects (galaxy selection and photometric redshift uncertainties), we first confirm that the observed ∼15 comoving Mpc-scale galaxy clustering is consistent with ΛCDM models. Using further the relation between high-z overdensity and the present day cluster mass calibrated in these matched simulations, we found 36 candidate structures at 1.6 < z < 3.1, showing overdensities consistent with the progenitors of M z = 0 ∼ 10 15 M ☉ clusters. Taking into account the significant upward scattering of lower mass structures, the probabilities for the candidates to have at least M z= 0 ∼ 10 14 M ☉ are ∼70%. For each structure, about 15%-40% of photometric galaxy candidates are expected to be true protocluster members that will merge into a cluster-scale halo by z = 0. With solely photometric redshifts, we successfully rediscover two spectroscopically confirmed structures in this field, suggesting that our algorithm is robust. This work generates a large sample of uniformly selected protocluster candidates, providing rich targets for spectroscopic follow-up and subsequent studies of cluster formation. Meanwhile, it demonstrates the potential for probing early cluster formation with upcoming redshift surveys such as the Hobby-Eberly Telescope Dark Energy Experiment and the Subaru Prime Focus Spectrograph survey

  15. Instability and associated roll structure of Marangoni convection in high Prandtl number liquid bridge with large aspect ratio

    Science.gov (United States)

    Yano, T.; Nishino, K.; Kawamura, H.; Ueno, I.; Matsumoto, S.

    2015-02-01

    This paper reports the experimental results on the instability and associated roll structures (RSs) of Marangoni convection in liquid bridges formed under the microgravity environment on the International Space Station. The geometry of interest is high aspect ratio (AR = height/diameter ≥ 1.0) liquid bridges of high Prandtl number fluids (Pr = 67 and 207) suspended between coaxial disks heated differentially. The unsteady flow field and associated RSs were revealed with the three-dimensional particle tracking velocimetry. It is found that the flow field after the onset of instability exhibits oscillations with azimuthal mode number m = 1 and associated RSs traveling in the axial direction. The RSs travel in the same direction as the surface flow (co-flow direction) for 1.00 ≤ AR ≤ 1.25 while they travel in the opposite direction (counter-flow direction) for AR ≥ 1.50, thus showing the change of traveling directions with AR. This traveling direction for AR ≥ 1.50 is reversed to the co-flow direction when the temperature difference between the disks is increased to the condition far beyond the critical one. This change of traveling directions is accompanied by the increase of the oscillation frequency. The characteristics of the RSs for AR ≥ 1.50, such as the azimuthal mode of oscillation, the dimensionless oscillation frequency, and the traveling direction, are in reasonable agreement with those of the previous sounding rocket experiment for AR = 2.50 and those of the linear stability analysis of an infinite liquid bridge.

  16. Investigating the Randomness of Numbers

    Science.gov (United States)

    Pendleton, Kenn L.

    2009-01-01

    The use of random numbers is pervasive in today's world. Random numbers have practical applications in such far-flung arenas as computer simulations, cryptography, gambling, the legal system, statistical sampling, and even the war on terrorism. Evaluating the randomness of extremely large samples is a complex, intricate process. However, the…

  17. A LARGE NUMBER OF z > 6 GALAXIES AROUND A QSO AT z = 6.43: EVIDENCE FOR A PROTOCLUSTER?

    International Nuclear Information System (INIS)

    Utsumi, Yousuke; Kashikawa, Nobunari; Miyazaki, Satoshi; Komiyama, Yutaka; Goto, Tomotsugu; Furusawa, Hisanori; Overzier, Roderik

    2010-01-01

    QSOs have been thought to be important for tracing highly biased regions in the early universe, from which the present-day massive galaxies and galaxy clusters formed. While overdensities of star-forming galaxies have been found around QSOs at 2 6 is less clear. Previous studies with the Hubble Space Telescope (HST) have reported the detection of small excesses of faint dropout galaxies in some QSO fields, but these surveys probed a relatively small region surrounding the QSOs. To overcome this problem, we have observed the most distant QSO at z = 6.4 using the large field of view of the Suprime-Cam (34' x 27'). Newly installed red-sensitive fully depleted CCDs allowed us to select Lyman break galaxies (LBGs) at z ∼ 6.4 more efficiently. We found seven LBGs in the QSO field, whereas only one exists in a comparison field. The significance of this apparent excess is difficult to quantify without spectroscopic confirmation and additional control fields. The Poisson probability to find seven objects when one expects four is ∼10%, while the probability to find seven objects in one field and only one in the other is less than 0.4%, suggesting that the QSO field is significantly overdense relative to the control field. These conclusions are supported by a comparison with a cosmological smoothed particle hydrodynamics simulation which includes the higher order clustering of galaxies. We find some evidence that the LBGs are distributed in a ring-like shape centered on the QSO with a radius of ∼3 Mpc. There are no candidate LBGs within 2 Mpc from the QSO, i.e., galaxies are clustered around the QSO but appear to avoid the very center. These results suggest that the QSO is embedded in an overdense region when defined on a sufficiently large scale (i.e., larger than an HST/ACS pointing). This suggests that the QSO was indeed born in a massive halo. The central deficit of galaxies may indicate that (1) the strong UV radiation from the QSO suppressed galaxy formation in

  18. A dynamic response model for pressure sensors in continuum and high Knudsen number flows with large temperature gradients

    Science.gov (United States)

    Whitmore, Stephen A.; Petersen, Brian J.; Scott, David D.

    1996-01-01

    This paper develops a dynamic model for pressure sensors in continuum and rarefied flows with longitudinal temperature gradients. The model was developed from the unsteady Navier-Stokes momentum, energy, and continuity equations and was linearized using small perturbations. The energy equation was decoupled from momentum and continuity assuming a polytropic flow process. Rarefied flow conditions were accounted for using a slip flow boundary condition at the tubing wall. The equations were radially averaged and solved assuming gas properties remain constant along a small tubing element. This fundamental solution was used as a building block for arbitrary geometries where fluid properties may also vary longitudinally in the tube. The problem was solved recursively starting at the transducer and working upstream in the tube. Dynamic frequency response tests were performed for continuum flow conditions in the presence of temperature gradients. These tests validated the recursive formulation of the model. Model steady-state behavior was analyzed using the final value theorem. Tests were performed for rarefied flow conditions and compared to the model steady-state response to evaluate the regime of applicability. Model comparisons were excellent for Knudsen numbers up to 0.6. Beyond this point, molecular affects caused model analyses to become inaccurate.

  19. Effect of the Hartmann number on phase separation controlled by magnetic field for binary mixture system with large component ratio

    Science.gov (United States)

    Heping, Wang; Xiaoguang, Li; Duyang, Zang; Rui, Hu; Xingguo, Geng

    2017-11-01

    This paper presents an exploration for phase separation in a magnetic field using a coupled lattice Boltzmann method (LBM) with magnetohydrodynamics (MHD). The left vertical wall was kept at a constant magnetic field. Simulations were conducted by the strong magnetic field to enhance phase separation and increase the size of separated phases. The focus was on the effect of magnetic intensity by defining the Hartmann number (Ha) on the phase separation properties. The numerical investigation was carried out for different governing parameters, namely Ha and the component ratio of the mixed liquid. The effective morphological evolutions of phase separation in different magnetic fields were demonstrated. The patterns showed that the slant elliptical phases were created by increasing Ha, due to the formation and increase of magnetic torque and force. The dataset was rearranged for growth kinetics of magnetic phase separation in a plot by spherically averaged structure factor and the ratio of separated phases and total system. The results indicate that the increase in Ha can increase the average size of separated phases and accelerate the spinodal decomposition and domain growth stages. Specially for the larger component ratio of mixed phases, the separation degree was also significantly improved by increasing magnetic intensity. These numerical results provide guidance for setting the optimum condition for the phase separation induced by magnetic field.

  20. Technology interactions among low-carbon energy technologies: What can we learn from a large number of scenarios?

    International Nuclear Information System (INIS)

    McJeon, Haewon C.; Clarke, Leon; Kyle, Page; Wise, Marshall; Hackbarth, Andrew; Bryant, Benjamin P.; Lempert, Robert J.

    2011-01-01

    Advanced low-carbon energy technologies can substantially reduce the cost of stabilizing atmospheric carbon dioxide concentrations. Understanding the interactions between these technologies and their impact on the costs of stabilization can help inform energy policy decisions. Many previous studies have addressed this challenge by exploring a small number of representative scenarios that represent particular combinations of future technology developments. This paper uses a combinatorial approach in which scenarios are created for all combinations of the technology development assumptions that underlie a smaller, representative set of scenarios. We estimate stabilization costs for 768 runs of the Global Change Assessment Model (GCAM), based on 384 different combinations of assumptions about the future performance of technologies and two stabilization goals. Graphical depiction of the distribution of stabilization costs provides first-order insights about the full data set and individual technologies. We apply a formal scenario discovery method to obtain more nuanced insights about the combinations of technology assumptions most strongly associated with high-cost outcomes. Many of the fundamental insights from traditional representative scenario analysis still hold under this comprehensive combinatorial analysis. For example, the importance of carbon capture and storage (CCS) and the substitution effect among supply technologies are consistently demonstrated. The results also provide more clarity regarding insights not easily demonstrated through representative scenario analysis. For example, they show more clearly how certain supply technologies can provide a hedge against high stabilization costs, and that aggregate end-use efficiency improvements deliver relatively consistent stabilization cost reductions. Furthermore, the results indicate that a lack of CCS options combined with lower technological advances in the buildings sector or the transportation sector is

  1. The culture of numbers: the origins and development of statistics on science - DOI:10.3395/reciis.v2i1.160en

    Directory of Open Access Journals (Sweden)

    Benoît Godin

    2008-10-01

    Full Text Available Measuring science has become an ‘industry’. When, how and why did science come to be measured in the first place? How did a “cultural” activity – science – long reputed to be not amenable to statistics, come to be measured? The statistics owes its existence to the context of the time: 1 measuring the contribution of great men, among them scientists, to civilization, and improving the social conditions of scientists; then 2 science policy and the efficiency of investments in research. Before the 1920s, it was scientists themselves who conducted measurements on science. The statistics collected concerned men of science, or scientists, their demography and geography, their productivity and performance, and were used to promote what was called the advancement of science. In the 1940s and after, the kind of statistics collected changed completely. It was no longer scientists who collected them, but governments and their statistical bureaus. The most cherished statistics was thereafter money devoted to research and development (R&D.

  2. SVA retrotransposon insertion-associated deletion represents a novel mutational mechanism underlying large genomic copy number changes with non-recurrent breakpoints

    Science.gov (United States)

    2014-01-01

    Background Genomic disorders are caused by copy number changes that may exhibit recurrent breakpoints processed by nonallelic homologous recombination. However, region-specific disease-associated copy number changes have also been observed which exhibit non-recurrent breakpoints. The mechanisms underlying these non-recurrent copy number changes have not yet been fully elucidated. Results We analyze large NF1 deletions with non-recurrent breakpoints as a model to investigate the full spectrum of causative mechanisms, and observe that they are mediated by various DNA double strand break repair mechanisms, as well as aberrant replication. Further, two of the 17 NF1 deletions with non-recurrent breakpoints, identified in unrelated patients, occur in association with the concomitant insertion of SINE/variable number of tandem repeats/Alu (SVA) retrotransposons at the deletion breakpoints. The respective breakpoints are refractory to analysis by standard breakpoint-spanning PCRs and are only identified by means of optimized PCR protocols designed to amplify across GC-rich sequences. The SVA elements are integrated within SUZ12P intron 8 in both patients, and were mediated by target-primed reverse transcription of SVA mRNA intermediates derived from retrotranspositionally active source elements. Both SVA insertions occurred during early postzygotic development and are uniquely associated with large deletions of 1 Mb and 867 kb, respectively, at the insertion sites. Conclusions Since active SVA elements are abundant in the human genome and the retrotranspositional activity of many SVA source elements is high, SVA insertion-associated large genomic deletions encompassing many hundreds of kilobases could constitute a novel and as yet under-appreciated mechanism underlying large-scale copy number changes in the human genome. PMID:24958239

  3. Summary Health Statistics for U.S. Adults: National Health Interview Survey, 2009. Data from the National Health Interview Survey. Vital and Health Statistics. Series 10, Number 249. DHHS Publication No. (PHS) 2011-1577

    Science.gov (United States)

    Pleis, J. R.; Ward, B. W.; Lucas, J. W.

    2010-01-01

    Objectives: This report presents health statistics from the 2009 National Health Interview Survey (NHIS) for the civilian noninstitutionalized adult population, classified by sex, age, race and ethnicity, education, family income, poverty status, health insurance coverage, marital status, and place and region of residence. Estimates are presented…

  4. The statistical-inference approach to generalized thermodynamics

    International Nuclear Information System (INIS)

    Lavenda, B.H.; Scherer, C.

    1987-01-01

    Limit theorems, such as the central-limit theorem and the weak law of large numbers, are applicable to statistical thermodynamics for sufficiently large sample size of indipendent and identically distributed observations performed on extensive thermodynamic (chance) variables. The estimation of the intensive thermodynamic quantities is a problem in parametric statistical estimation. The normal approximation to the Gibbs' distribution is justified by the analysis of large deviations. Statistical thermodynamics is generalized to include the statistical estimation of variance as well as mean values

  5. Falling in the elderly: Do statistical models matter for performance criteria of fall prediction? Results from two large population-based studies.

    Science.gov (United States)

    Kabeshova, Anastasiia; Launay, Cyrille P; Gromov, Vasilii A; Fantino, Bruno; Levinoff, Elise J; Allali, Gilles; Beauchet, Olivier

    2016-01-01

    To compare performance criteria (i.e., sensitivity, specificity, positive predictive value, negative predictive value, area under receiver operating characteristic curve and accuracy) of linear and non-linear statistical models for fall risk in older community-dwellers. Participants were recruited in two large population-based studies, "Prévention des Chutes, Réseau 4" (PCR4, n=1760, cross-sectional design, retrospective collection of falls) and "Prévention des Chutes Personnes Agées" (PCPA, n=1765, cohort design, prospective collection of falls). Six linear statistical models (i.e., logistic regression, discriminant analysis, Bayes network algorithm, decision tree, random forest, boosted trees), three non-linear statistical models corresponding to artificial neural networks (multilayer perceptron, genetic algorithm and neuroevolution of augmenting topologies [NEAT]) and the adaptive neuro fuzzy interference system (ANFIS) were used. Falls ≥1 characterizing fallers and falls ≥2 characterizing recurrent fallers were used as outcomes. Data of studies were analyzed separately and together. NEAT and ANFIS had better performance criteria compared to other models. The highest performance criteria were reported with NEAT when using PCR4 database and falls ≥1, and with both NEAT and ANFIS when pooling data together and using falls ≥2. However, sensitivity and specificity were unbalanced. Sensitivity was higher than specificity when identifying fallers, whereas the converse was found when predicting recurrent fallers. Our results showed that NEAT and ANFIS were non-linear statistical models with the best performance criteria for the prediction of falls but their sensitivity and specificity were unbalanced, underscoring that models should be used respectively for the screening of fallers and the diagnosis of recurrent fallers. Copyright © 2015 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  6. Escape from washing out of baryon number in a two-zero-texture general Zee model compatible with the large mixing angle MSW solution

    International Nuclear Information System (INIS)

    Hasegawa, K.; Lim, C.S.; Ogure, K.

    2003-01-01

    We propose a two-zero-texture general Zee model, compatible with the large mixing angle Mikheyev-Smirnov-Wolfenstein solution. The washing out of the baryon number does not occur in this model for an adequate parameter range. We check the consistency of a model with the constraints coming from flavor changing neutral current processes, the recent cosmic microwave background observation, and the Z-burst scenario

  7. Escape from washing out of baryon number in a two-zero-texture general Zee model compatible with the large mixing angle MSW solution

    Science.gov (United States)

    Hasegawa, K.; Lim, C. S.; Ogure, K.

    2003-09-01

    We propose a two-zero-texture general Zee model, compatible with the large mixing angle Mikheyev-Smirnov-Wolfenstein solution. The washing out of the baryon number does not occur in this model for an adequate parameter range. We check the consistency of a model with the constraints coming from flavor changing neutral current processes, the recent cosmic microwave background observation, and the Z-burst scenario.

  8. Escape from washing out of baryon number in a two-zero-texture general Zee model compatible with the large mixing angle MSW solution

    OpenAIRE

    Hasegawa, K.; Lim, C. S.; Ogure, K.

    2003-01-01

    We propose a two-zero-texture general Zee model, compatible with the large mixing angle Mikheyev-Smirnov-Wolfenstein solution. The washing out of the baryon number does not occur in this model for an adequate parameter range. We check the consistency of a model with the constraints coming from flavor changing neutral current processes, the recent cosmic microwave background observation, and the Z-burst scenario.

  9. Remote sensing estimation of the total phosphorus concentration in a large lake using band combinations and regional multivariate statistical modeling techniques.

    Science.gov (United States)

    Gao, Yongnian; Gao, Junfeng; Yin, Hongbin; Liu, Chuansheng; Xia, Ting; Wang, Jing; Huang, Qi

    2015-03-15

    Remote sensing has been widely used for ater quality monitoring, but most of these monitoring studies have only focused on a few water quality variables, such as chlorophyll-a, turbidity, and total suspended solids, which have typically been considered optically active variables. Remote sensing presents a challenge in estimating the phosphorus concentration in water. The total phosphorus (TP) in lakes has been estimated from remotely sensed observations, primarily using the simple individual band ratio or their natural logarithm and the statistical regression method based on the field TP data and the spectral reflectance. In this study, we investigated the possibility of establishing a spatial modeling scheme to estimate the TP concentration of a large lake from multi-spectral satellite imagery using band combinations and regional multivariate statistical modeling techniques, and we tested the applicability of the spatial modeling scheme. The results showed that HJ-1A CCD multi-spectral satellite imagery can be used to estimate the TP concentration in a lake. The correlation and regression analysis showed a highly significant positive relationship between the TP concentration and certain remotely sensed combination variables. The proposed modeling scheme had a higher accuracy for the TP concentration estimation in the large lake compared with the traditional individual band ratio method and the whole-lake scale regression-modeling scheme. The TP concentration values showed a clear spatial variability and were high in western Lake Chaohu and relatively low in eastern Lake Chaohu. The northernmost portion, the northeastern coastal zone and the southeastern portion of western Lake Chaohu had the highest TP concentrations, and the other regions had the lowest TP concentration values, except for the coastal zone of eastern Lake Chaohu. These results strongly suggested that the proposed modeling scheme, i.e., the band combinations and the regional multivariate

  10. Statistical Computing

    Indian Academy of Sciences (India)

    inference and finite population sampling. Sudhakar Kunte. Elements of statistical computing are discussed in this series. ... which captain gets an option to decide whether to field first or bat first ... may of course not be fair, in the sense that the team which wins ... describe two methods of drawing a random number between 0.

  11. Statistical Model of Extreme Shear

    DEFF Research Database (Denmark)

    Larsen, Gunner Chr.; Hansen, Kurt Schaldemose

    2004-01-01

    In order to continue cost-optimisation of modern large wind turbines, it is important to continously increase the knowledge on wind field parameters relevant to design loads. This paper presents a general statistical model that offers site-specific prediction of the probability density function...... by a model that, on a statistically consistent basis, describe the most likely spatial shape of an extreme wind shear event. Predictions from the model have been compared with results from an extreme value data analysis, based on a large number of high-sampled full-scale time series measurements...... are consistent, given the inevitabel uncertainties associated with model as well as with the extreme value data analysis. Keywords: Statistical model, extreme wind conditions, statistical analysis, turbulence, wind loading, statistical analysis, turbulence, wind loading, wind shear, wind turbines....

  12. How much can the number of jabiru stork (Ciconiidae nests vary due to change of flood extension in a large Neotropical floodplain?

    Directory of Open Access Journals (Sweden)

    Guilherme Mourão

    2010-10-01

    Full Text Available The jabiru stork, Jabiru mycteria (Lichtenstein, 1819, a large, long-legged wading bird occurring in lowland wetlands from southern Mexico to northern Argentina, is considered endangered in a large portion of its distribution range. We conducted aerial surveys to estimate the number of jabiru active nests in the Brazilian Pantanal (140,000 km² in September of 1991-1993, 1998, 2000-2002, and 2004. Corrected densities of active nests were regressed against the annual hydrologic index (AHI, an index of flood extension in the Pantanal based on the water level of the Paraguay River. Annual nest density was a non-linear function of the AHI, modeled by the equation 6.5 · 10-8 · AHI1.99 (corrected r² = 0.72, n = 7. We applied this model to the AHI between 1900 and 2004. The results indicate that the number of jabiru nests may have varied from about 220 in 1971 to more than 23,000 in the nesting season of 1921, and the estimates for our study period (1991 to 2004 averaged about 12,400 nests. Our model indicates that the inter-annual variations in flooding extent can determine dramatic changes in the number of active jabiru nests. Since the jabiru stork responds negatively to drier conditions in the Pantanal, direct human-induced changes in the hydrological patterns, as well as the effects of global climate change, may strongly jeopardize the population in the region.

  13. The Effect of Unequal Samples, Heterogeneity of Covariance Matrices, and Number of Variables on Discriminant Analysis Classification Tables and Related Statistics.

    Science.gov (United States)

    Spearing, Debra; Woehlke, Paula

    To assess the effect on discriminant analysis in terms of correct classification into two groups, the following parameters were systematically altered using Monte Carlo techniques: sample sizes; proportions of one group to the other; number of independent variables; and covariance matrices. The pairing of the off diagonals (or covariances) with…

  14. Aerodynamic Effects of High Turbulence Intensity on a Variable-Speed Power-Turbine Blade With Large Incidence and Reynolds Number Variations

    Science.gov (United States)

    Flegel, Ashlie B.; Giel, Paul W.; Welch, Gerard E.

    2014-01-01

    The effects of high inlet turbulence intensity on the aerodynamic performance of a variable speed power turbine blade are examined over large incidence and Reynolds number ranges. These results are compared to previous measurements made in a low turbulence environment. Both high and low turbulence studies were conducted in the NASA Glenn Research Center Transonic Turbine Blade Cascade Facility. The purpose of the low inlet turbulence study was to examine the transitional flow effects that are anticipated at cruise Reynolds numbers. The current study extends this to LPT-relevant turbulence levels while perhaps sacrificing transitional flow effects. Assessing the effects of turbulence at these large incidence and Reynolds number variations complements the existing database. Downstream total pressure and exit angle data were acquired for 10 incidence angles ranging from +15.8deg to -51.0deg. For each incidence angle, data were obtained at five flow conditions with the exit Reynolds number ranging from 2.12×10(exp 5) to 2.12×10(exp 6) and at a design exit Mach number of 0.72. In order to achieve the lowest Reynolds number, the exit Mach number was reduced to 0.35 due to facility constraints. The inlet turbulence intensity, Tu, was measured using a single-wire hotwire located 0.415 axial-chord upstream of the blade row. The inlet turbulence levels ranged from 8 to 15 percent for the current study. Tu measurements were also made farther upstream so that turbulence decay rates could be calculated as needed for computational inlet boundary conditions. Downstream flow field measurements were obtained using a pneumatic five-hole pitch/yaw probe located in a survey plane 7 percent axial chord aft of the blade trailing edge and covering three blade passages. Blade and endwall static pressures were acquired for each flow condition as well. The blade loading data show that the suction surface separation that was evident at many of the low Tu conditions has been eliminated. At

  15. Multiple-relaxation-time lattice Boltzmann model for incompressible miscible flow with large viscosity ratio and high Péclet number

    Science.gov (United States)

    Meng, Xuhui; Guo, Zhaoli

    2015-10-01

    A lattice Boltzmann model with a multiple-relaxation-time (MRT) collision operator is proposed for incompressible miscible flow with a large viscosity ratio as well as a high Péclet number in this paper. The equilibria in the present model are motivated by the lattice kinetic scheme previously developed by Inamuro et al. [Philos. Trans. R. Soc. London, Ser. A 360, 477 (2002), 10.1098/rsta.2001.0942]. The fluid viscosity and diffusion coefficient depend on both the corresponding relaxation times and additional adjustable parameters in this model. As a result, the corresponding relaxation times can be adjusted in proper ranges to enhance the performance of the model. Numerical validations of the Poiseuille flow and a diffusion-reaction problem demonstrate that the proposed model has second-order accuracy in space. Thereafter, the model is used to simulate flow through a porous medium, and the results show that the proposed model has the advantage to obtain a viscosity-independent permeability, which makes it a robust method for simulating flow in porous media. Finally, a set of simulations are conducted on the viscous miscible displacement between two parallel plates. The results reveal that the present model can be used to simulate, to a high level of accuracy, flows with large viscosity ratios and/or high Péclet numbers. Moreover, the present model is shown to provide superior stability in the limit of high kinematic viscosity. In summary, the numerical results indicate that the present lattice Boltzmann model is an ideal numerical tool for simulating flow with a large viscosity ratio and/or a high Péclet number.

  16. Influence of Extrinsic Information Scaling Coefficient on Double-Iterative Decoding Algorithm for Space-Time Turbo Codes with Large Number of Antennas

    Directory of Open Access Journals (Sweden)

    TRIFINA, L.

    2011-02-01

    Full Text Available This paper analyzes the extrinsic information scaling coefficient influence on double-iterative decoding algorithm for space-time turbo codes with large number of antennas. The max-log-APP algorithm is used, scaling both the extrinsic information in the turbo decoder and the one used at the input of the interference-canceling block. Scaling coefficients of 0.7 or 0.75 lead to a 0.5 dB coding gain compared to the no-scaling case, for one or more iterations to cancel the spatial interferences.

  17. Dogs Have the Most Neurons, Though Not the Largest Brain: Trade-Off between Body Mass and Number of Neurons in the Cerebral Cortex of Large Carnivoran Species

    Directory of Open Access Journals (Sweden)

    Débora Jardim-Messeder

    2017-12-01

    Full Text Available Carnivorans are a diverse group of mammals that includes carnivorous, omnivorous and herbivorous, domesticated and wild species, with a large range of brain sizes. Carnivory is one of several factors expected to be cognitively demanding for carnivorans due to a requirement to outsmart larger prey. On the other hand, large carnivoran species have high hunting costs and unreliable feeding patterns, which, given the high metabolic cost of brain neurons, might put them at risk of metabolic constraints regarding how many brain neurons they can afford, especially in the cerebral cortex. For a given cortical size, do carnivoran species have more cortical neurons than the herbivorous species they prey upon? We find they do not; carnivorans (cat, mongoose, dog, hyena, lion share with non-primates, including artiodactyls (the typical prey of large carnivorans, roughly the same relationship between cortical mass and number of neurons, which suggests that carnivorans are subject to the same evolutionary scaling rules as other non-primate clades. However, there are a few important exceptions. Carnivorans stand out in that the usual relationship between larger body, larger cortical mass and larger number of cortical neurons only applies to small and medium-sized species, and not beyond dogs: we find that the golden retriever dog has more cortical neurons than the striped hyena, African lion and even brown bear, even though the latter species have up to three times larger cortices than dogs. Remarkably, the brown bear cerebral cortex, the largest examined, only has as many neurons as the ten times smaller cat cerebral cortex, although it does have the expected ten times as many non-neuronal cells in the cerebral cortex compared to the cat. We also find that raccoons have dog-like numbers of neurons in their cat-sized brain, which makes them comparable to primates in neuronal density. Comparison of domestic and wild species suggests that the neuronal

  18. Enhancement of phase space density by increasing trap anisotropy in a magneto-optical trap with a large number of atoms

    International Nuclear Information System (INIS)

    Vengalattore, M.; Conroy, R.S.; Prentiss, M.G.

    2004-01-01

    The phase space density of dense, cylindrical clouds of atoms in a 2D magneto-optic trap is investigated. For a large number of trapped atoms (>10 8 ), the density of a spherical cloud is limited by photon reabsorption. However, as the atom cloud is deformed to reduce the radial optical density, the temperature of the atoms decreases due to the suppression of multiple scattering leading to an increase in the phase space density. A density of 2x10 -4 has been achieved in a magneto-optic trap containing 2x10 8 atoms

  19. Timoides agassizii Bigelow, 1904, little-known hydromedusa (Cnidaria), appears briefly in large numbers off Oman, March 2011, with additional notes about species of the genus Timoides.

    Science.gov (United States)

    Purushothaman, Jasmine; Kharusi, Lubna Al; Mills, Claudia E; Ghielani, Hamed; Marzouki, Mohammad Al

    2013-12-11

    A bloom of the hydromedusan jellyfish, Timoides agassizii, occurred in February 2011 off the coast of Sohar, Al Batinah, Sultanate of Oman, in the Gulf of Oman. This species was first observed in 1902 in great numbers off Haddummati Atoll in the Maldive Islands in the Indian Ocean and has rarely been seen since. The species appeared briefly in large numbers off Oman in 2011 and subsequent observation of our 2009 samples of zooplankton from Sohar revealed that it was also present in low numbers (two collected) in one sample in 2009; these are the first records in the Indian Ocean north of the Maldives. Medusae collected off Oman were almost identical to those recorded previously from the Maldive Islands, Papua New Guinea, the Marshall Islands, Guam, the South China Sea, and Okinawa. T. agassizii is a species that likely lives for several months. It was present in our plankton samples together with large numbers of the oceanic siphonophore Physalia physalis only during a single month's samples, suggesting that the temporary bloom off Oman was likely due to the arrival of mature, open ocean medusae into nearshore waters. We see no evidence that T. agassizii has established a new population along Oman, since if so, it would likely have been present in more than one sample period. We are unable to deduce further details of the life cycle of this species from blooms of many mature individuals nearshore, about a century apart. Examination of a single damaged T. agassizii medusa from Guam, calls into question the existence of its congener, T. latistyla, known only from a single specimen.

  20. Multi-cluster processor operating only select number of clusters during each phase based on program statistic monitored at predetermined intervals

    Science.gov (United States)

    Balasubramonian, Rajeev [Sandy, UT; Dwarkadas, Sandhya [Rochester, NY; Albonesi, David [Ithaca, NY

    2009-02-10

    In a processor having multiple clusters which operate in parallel, the number of clusters in use can be varied dynamically. At the start of each program phase, the configuration option for an interval is run to determine the optimal configuration, which is used until the next phase change is detected. The optimum instruction interval is determined by starting with a minimum interval and doubling it until a low stability factor is reached.

  1. Statistical inference

    CERN Document Server

    Rohatgi, Vijay K

    2003-01-01

    Unified treatment of probability and statistics examines and analyzes the relationship between the two fields, exploring inferential issues. Numerous problems, examples, and diagrams--some with solutions--plus clear-cut, highlighted summaries of results. Advanced undergraduate to graduate level. Contents: 1. Introduction. 2. Probability Model. 3. Probability Distributions. 4. Introduction to Statistical Inference. 5. More on Mathematical Expectation. 6. Some Discrete Models. 7. Some Continuous Models. 8. Functions of Random Variables and Random Vectors. 9. Large-Sample Theory. 10. General Meth

  2. SU-E-T-230: Creating a Large Number of Focused Beams with Variable Patient Head Tilt to Improve Dose Fall-Off for Brain Radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Chiu, J; Ma, L [Department of Radiation Oncology, University of California San Francisco School of Medicine, San Francisco, CA (United States)

    2015-06-15

    Purpose: To develop a treatment delivery and planning strategy by increasing the number of beams to minimize dose to brain tissue surrounding a target, while maximizing dose coverage to the target. Methods: We analyzed 14 different treatment plans via Leksell PFX and 4C. For standardization, single tumor cases were chosen. Original treatment plans were compared with two optimized plans. The number of beams was increased in treatment plans by varying tilt angles of the patient head, while maintaining original isocenter and the beam positions in the x-, y- and z-axes, collimator size, and beam blocking. PFX optimized plans increased beam numbers with three pre-set tilt angles, 70, 90, 110, and 4C optimized plans increased beam numbers with tilt angles increasing arbitrarily from range of 30 to 150 degrees. Optimized treatment plans were compared dosimetrically with original treatment plans. Results: Comparing total normal tissue isodose volumes between original and optimized plans, the low-level percentage isodose volumes decreased in all plans. Despite the addition of multiple beams up to a factor of 25, beam-on times for 1 tilt angle versus 3 or more tilt angles were comparable (<1 min.). In 64% (9/14) of the studied cases, the volume percentage decrease by >5%, with the highest value reaching 19%. The addition of more tilt angles correlates to a greater decrease in normal brain irradiated volume. Selectivity and coverage for original and optimized plans remained comparable. Conclusion: Adding large number of additional focused beams with variable patient head tilt shows improvement for dose fall-off for brain radiosurgery. The study demonstrates technical feasibility of adding beams to decrease target volume.

  3. SU-E-T-230: Creating a Large Number of Focused Beams with Variable Patient Head Tilt to Improve Dose Fall-Off for Brain Radiosurgery

    International Nuclear Information System (INIS)

    Chiu, J; Ma, L

    2015-01-01

    Purpose: To develop a treatment delivery and planning strategy by increasing the number of beams to minimize dose to brain tissue surrounding a target, while maximizing dose coverage to the target. Methods: We analyzed 14 different treatment plans via Leksell PFX and 4C. For standardization, single tumor cases were chosen. Original treatment plans were compared with two optimized plans. The number of beams was increased in treatment plans by varying tilt angles of the patient head, while maintaining original isocenter and the beam positions in the x-, y- and z-axes, collimator size, and beam blocking. PFX optimized plans increased beam numbers with three pre-set tilt angles, 70, 90, 110, and 4C optimized plans increased beam numbers with tilt angles increasing arbitrarily from range of 30 to 150 degrees. Optimized treatment plans were compared dosimetrically with original treatment plans. Results: Comparing total normal tissue isodose volumes between original and optimized plans, the low-level percentage isodose volumes decreased in all plans. Despite the addition of multiple beams up to a factor of 25, beam-on times for 1 tilt angle versus 3 or more tilt angles were comparable (<1 min.). In 64% (9/14) of the studied cases, the volume percentage decrease by >5%, with the highest value reaching 19%. The addition of more tilt angles correlates to a greater decrease in normal brain irradiated volume. Selectivity and coverage for original and optimized plans remained comparable. Conclusion: Adding large number of additional focused beams with variable patient head tilt shows improvement for dose fall-off for brain radiosurgery. The study demonstrates technical feasibility of adding beams to decrease target volume

  4. Global repeat discovery and estimation of genomic copy number in a large, complex genome using a high-throughput 454 sequence survey

    Directory of Open Access Journals (Sweden)

    Varala Kranthi

    2007-05-01

    Full Text Available Abstract Background Extensive computational and database tools are available to mine genomic and genetic databases for model organisms, but little genomic data is available for many species of ecological or agricultural significance, especially those with large genomes. Genome surveys using conventional sequencing techniques are powerful, particularly for detecting sequences present in many copies per genome. However these methods are time-consuming and have potential drawbacks. High throughput 454 sequencing provides an alternative method by which much information can be gained quickly and cheaply from high-coverage surveys of genomic DNA. Results We sequenced 78 million base-pairs of randomly sheared soybean DNA which passed our quality criteria. Computational analysis of the survey sequences provided global information on the abundant repetitive sequences in soybean. The sequence was used to determine the copy number across regions of large genomic clones or contigs and discover higher-order structures within satellite repeats. We have created an annotated, online database of sequences present in multiple copies in the soybean genome. The low bias of pyrosequencing against repeat sequences is demonstrated by the overall composition of the survey data, which matches well with past estimates of repetitive DNA content obtained by DNA re-association kinetics (Cot analysis. Conclusion This approach provides a potential aid to conventional or shotgun genome assembly, by allowing rapid assessment of copy number in any clone or clone-end sequence. In addition, we show that partial sequencing can provide access to partial protein-coding sequences.

  5. Use of Two-Body Correlated Basis Functions with van der Waals Interaction to Study the Shape-Independent Approximation for a Large Number of Trapped Interacting Bosons

    Science.gov (United States)

    Lekala, M. L.; Chakrabarti, B.; Das, T. K.; Rampho, G. J.; Sofianos, S. A.; Adam, R. M.; Haldar, S. K.

    2017-05-01

    We study the ground-state and the low-lying excitations of a trapped Bose gas in an isotropic harmonic potential for very small (˜ 3) to very large (˜ 10^7) particle numbers. We use the two-body correlated basis functions and the shape-dependent van der Waals interaction in our many-body calculations. We present an exhaustive study of the effect of inter-atomic correlations and the accuracy of the mean-field equations considering a wide range of particle numbers. We calculate the ground-state energy and the one-body density for different values of the van der Waals parameter C6. We compare our results with those of the modified Gross-Pitaevskii results, the correlated Hartree hypernetted-chain equations (which also utilize the two-body correlated basis functions), as well as of the diffusion Monte Carlo for hard sphere interactions. We observe the effect of the attractive tail of the van der Waals potential in the calculations of the one-body density over the truly repulsive zero-range potential as used in the Gross-Pitaevskii equation and discuss the finite-size effects. We also present the low-lying collective excitations which are well described by a hydrodynamic model in the large particle limit.

  6. Evaluation of list-mode ordered subset expectation maximization image reconstruction for pixelated solid-state compton gamma camera with large number of channels

    Science.gov (United States)

    Kolstein, M.; De Lorenzo, G.; Chmeissani, M.

    2014-04-01

    The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For Compton camera, especially with a large number of readout channels, image reconstruction presents a big challenge. In this work, results are presented for the List-Mode Ordered Subset Expectation Maximization (LM-OSEM) image reconstruction algorithm on simulated data with the VIP Compton camera design. For the simulation, all realistic contributions to the spatial resolution are taken into account, including the Doppler broadening effect. The results show that even with a straightforward implementation of LM-OSEM, good images can be obtained for the proposed Compton camera design. Results are shown for various phantoms, including extended sources and with a distance between the field of view and the first detector plane equal to 100 mm which corresponds to a realistic nuclear medicine environment.

  7. Comparative efficacy of tulathromycin versus a combination of florfenicol-oxytetracycline in the treatment of undifferentiated respiratory disease in large numbers of sheep

    Directory of Open Access Journals (Sweden)

    Mohsen Champour

    2015-09-01

    Full Text Available The objective of this study was to compare the efficacy of tulathromycin (TUL with a combination of florfenicol (FFC and long-acting oxytetracycline (LAOTC in the treatment of naturally occurring undifferentiated respiratory diseases in large numbers of sheep. In this study, seven natural outbreaks of sheep pneumonia in Garmsar, Iran were considered. From these outbreaks, 400 sheep exhibiting the signs of respiratory diseases were selected, and the sheep were randomly divided into two equal groups. The first group was treated with a single injection of TUL (dosed at 2.5 mg/kg body weight, and the second group was treated with concurrent injections of FFC (dosed at 40 mg/kg bwt and LAOTC (dosed at 20 mg/kg bwt. In the first group, 186 (93% sheep were found to be cured 5 days after the injection, and 14 (7% sheep needed further treatment, of which 6 (3% were cured, and 8 (4% died. In the second group, 172 (86% sheep were cured after the injections, but 28 (14% sheep needed further treatment, of which 10 (5% were cured, and 18 (9% died. This study revealed that TUL was more efficacious as compared to the combined treatment using FFC and LAOTC. As the first report, this field trial describes the successful treatment of undifferentiated respiratory diseases in large numbers of sheep. Thus, TUL can be used for the treatment of undifferentiated respiratory diseases in sheep. [J Adv Vet Anim Res 2015; 2(3.000: 279-284

  8. On the Required Number of Antennas in a Point-to-Point Large-but-Finite MIMO System: Outage-Limited Scenario

    KAUST Repository

    Makki, Behrooz

    2016-03-22

    This paper investigates the performance of the point-To-point multiple-input-multiple-output (MIMO) systems in the presence of a large but finite numbers of antennas at the transmitters and/or receivers. Considering the cases with and without hybrid automatic repeat request (HARQ) feedback, we determine the minimum numbers of the transmit/receive antennas, which are required to satisfy different outage probability constraints. Our results are obtained for different fading conditions and the effect of the power amplifiers efficiency/feedback error probability on the performance of the MIMO-HARQ systems is analyzed. Then, we use some recent results on the achievable rates of finite block-length codes, to analyze the effect of the codewords lengths on the system performance. Moreover, we derive closed-form expressions for the asymptotic performance of the MIMO-HARQ systems when the number of antennas increases. Our analytical and numerical results show that different outage requirements can be satisfied with relatively few transmit/receive antennas. © 1972-2012 IEEE.

  9. Statistical Model of Extreme Shear

    DEFF Research Database (Denmark)

    Hansen, Kurt Schaldemose; Larsen, Gunner Chr.

    2005-01-01

    In order to continue cost-optimisation of modern large wind turbines, it is important to continuously increase the knowledge of wind field parameters relevant to design loads. This paper presents a general statistical model that offers site-specific prediction of the probability density function...... by a model that, on a statistically consistent basis, describes the most likely spatial shape of an extreme wind shear event. Predictions from the model have been compared with results from an extreme value data analysis, based on a large number of full-scale measurements recorded with a high sampling rate...

  10. Statistical utilitarianism

    OpenAIRE

    Pivato, Marcus

    2013-01-01

    We show that, in a sufficiently large population satisfying certain statistical regularities, it is often possible to accurately estimate the utilitarian social welfare function, even if we only have very noisy data about individual utility functions and interpersonal utility comparisons. In particular, we show that it is often possible to identify an optimal or close-to-optimal utilitarian social choice using voting rules such as the Borda rule, approval voting, relative utilitarianism, or a...

  11. Long-term changes in nutrients and mussel stocks are related to numbers of breeding eiders Somateria mollissima at a large Baltic colony.

    Directory of Open Access Journals (Sweden)

    Karsten Laursen

    Full Text Available BACKGROUND: The Baltic/Wadden Sea eider Somateria mollissima flyway population is decreasing, and this trend is also reflected in the large eider colony at Christiansø situated in the Baltic Sea. This colony showed a 15-fold increase from 1925 until the mid-1990's, followed by a rapid decline in recent years, although the causes of this trend remain unknown. Most birds from the colony winter in the Wadden Sea, from which environmental data and information on the size of the main diet, the mussel Mytilus edulis stock exists. We hypothesised that changes in nutrients and water temperature in the Wadden Sea had an effect on the ecosystem affecting the size of mussel stocks, the principal food item for eiders, thereby influencing the number of breeding eider in the Christiansø colony. METHODOLOGY/PRINCIPAL FINDING: A positive relationship between the amount of fertilizer used by farmers and the concentration of phosphorus in the Wadden Sea (with a time lag of one year allowed analysis of the predictions concerning effects of nutrients for the period 1925-2010. There was (1 increasing amounts of fertilizer used in agriculture and this increased the amount of nutrients in the marine environment thereby increasing the mussel stocks in the Wadden Sea. (2 The number of eiders at Christiansø increased when the amount of fertilizer increased. Finally (3 the number of eiders in the colony at Christiansø increased with the amount of mussel stocks in the Wadden Sea. CONCLUSIONS/SIGNIFICANCE: The trend in the number of eiders at Christiansø is representative for the entire flyway population, and since nutrient reduction in the marine environment occurs in most parts of Northwest Europe, we hypothesize that this environmental candidate parameter is involved in the overall regulation of the Baltic/Wadden Sea eider population during recent decades.

  12. Aerodynamic Effects of Turbulence Intensity on a Variable-Speed Power-Turbine Blade with Large Incidence and Reynolds Number Variations

    Science.gov (United States)

    Flegel, Ashlie Brynn; Giel, Paul W.; Welch, Gerard E.

    2014-01-01

    The effects of inlet turbulence intensity on the aerodynamic performance of a variable speed power turbine blade are examined over large incidence and Reynolds number ranges. Both high and low turbulence studies were conducted in the NASA Glenn Research Center Transonic Turbine Blade Cascade Facility. The purpose of the low inlet turbulence study was to examine the transitional flow effects that are anticipated at cruise Reynolds numbers. The high turbulence study extends this to LPT-relevant turbulence levels while perhaps sacrificing transitional flow effects. Downstream total pressure and exit angle data were acquired for ten incidence angles ranging from +15.8 to 51.0. For each incidence angle, data were obtained at five flow conditions with the exit Reynolds number ranging from 2.12105 to 2.12106 and at a design exit Mach number of 0.72. In order to achieve the lowest Reynolds number, the exit Mach number was reduced to 0.35 due to facility constraints. The inlet turbulence intensity, Tu, was measured using a single-wire hotwire located 0.415 axial-chord upstream of the blade row. The inlet turbulence levels ranged from 0.25 - 0.4 for the low Tu tests and 8- 15 for the high Tu study. Tu measurements were also made farther upstream so that turbulence decay rates could be calculated as needed for computational inlet boundary conditions. Downstream flow field measurements were obtained using a pneumatic five-hole pitchyaw probe located in a survey plane 7 axial chord aft of the blade trailing edge and covering three blade passages. Blade and endwall static pressures were acquired for each flow condition as well. The blade loading data show that the suction surface separation that was evident at many of the low Tu conditions has been eliminated. At the extreme positive and negative incidence angles, the data show substantial differences in the exit flow field. These differences are attributable to both the higher inlet Tu directly and to the thinner inlet endwall

  13. The structure of Diagnostic and Statistical Manual of Mental Disorders (4th edition, text revision) personality disorder symptoms in a large national sample.

    Science.gov (United States)

    Trull, Timothy J; Vergés, Alvaro; Wood, Phillip K; Jahng, Seungmin; Sher, Kenneth J

    2012-10-01

    We examined the latent structure underlying the criteria for DSM-IV-TR (American Psychiatric Association, 2000, Diagnostic and statistical manual of mental disorders (4th ed., text revision). Washington, DC: Author.) personality disorders in a large nationally representative sample of U.S. adults. Personality disorder symptom data were collected using a structured diagnostic interview from approximately 35,000 adults assessed over two waves of data collection in the National Epidemiologic Survey on Alcohol and Related Conditions. Our analyses suggested that a seven-factor solution provided the best fit for the data, and these factors were marked primarily by one or at most two personality disorder criteria sets. A series of regression analyses that used external validators tapping Axis I psychopathology, treatment for mental health problems, functioning scores, interpersonal conflict, and suicidal ideation and behavior provided support for the seven-factor solution. We discuss these findings in the context of previous studies that have examined the structure underlying the personality disorder criteria as well as the current proposals for DSM-5 personality disorders. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

  14. Fractional statistics and fractional quantized Hall effect

    International Nuclear Information System (INIS)

    Tao, R.; Wu, Y.S.

    1985-01-01

    The authors suggest that the origin of the odd-denominator rule observed in the fractional quantized Hall effect (FQHE) may lie in fractional statistics which govern quasiparticles in FQHE. A theorem concerning statistics of clusters of quasiparticles implies that fractional statistics do not allow coexistence of a large number of quasiparticles at fillings with an even denominator. Thus, no Hall plateau can be formed at these fillings, regardless of the presence of an energy gap. 15 references

  15. Earthquake number forecasts testing

    Science.gov (United States)

    Kagan, Yan Y.

    2017-10-01

    We study the distributions of earthquake numbers in two global earthquake catalogues: Global Centroid-Moment Tensor and Preliminary Determinations of Epicenters. The properties of these distributions are especially required to develop the number test for our forecasts of future seismic activity rate, tested by the Collaboratory for Study of Earthquake Predictability (CSEP). A common assumption, as used in the CSEP tests, is that the numbers are described by the Poisson distribution. It is clear, however, that the Poisson assumption for the earthquake number distribution is incorrect, especially for the catalogues with a lower magnitude threshold. In contrast to the one-parameter Poisson distribution so widely used to describe earthquake occurrences, the negative-binomial distribution (NBD) has two parameters. The second parameter can be used to characterize the clustering or overdispersion of a process. We also introduce and study a more complex three-parameter beta negative-binomial distribution. We investigate the dependence of parameters for both Poisson and NBD distributions on the catalogue magnitude threshold and on temporal subdivision of catalogue duration. First, we study whether the Poisson law can be statistically rejected for various catalogue subdivisions. We find that for most cases of interest, the Poisson distribution can be shown to be rejected statistically at a high significance level in favour of the NBD. Thereafter, we investigate whether these distributions fit the observed distributions of seismicity. For this purpose, we study upper statistical moments of earthquake numbers (skewness and kurtosis) and compare them to the theoretical values for both distributions. Empirical values for the skewness and the kurtosis increase for the smaller magnitude threshold and increase with even greater intensity for small temporal subdivision of catalogues. The Poisson distribution for large rate values approaches the Gaussian law, therefore its skewness

  16. A large scale survey reveals that chromosomal copy-number alterations significantly affect gene modules involved in cancer initiation and progression

    Directory of Open Access Journals (Sweden)

    Cigudosa Juan C

    2011-05-01

    Full Text Available Abstract Background Recent observations point towards the existence of a large number of neighborhoods composed of functionally-related gene modules that lie together in the genome. This local component in the distribution of the functionality across chromosomes is probably affecting the own chromosomal architecture by limiting the possibilities in which genes can be arranged and distributed across the genome. As a direct consequence of this fact it is therefore presumable that diseases such as cancer, harboring DNA copy number alterations (CNAs, will have a symptomatology strongly dependent on modules of functionally-related genes rather than on a unique "important" gene. Methods We carried out a systematic analysis of more than 140,000 observations of CNAs in cancers and searched by enrichments in gene functional modules associated to high frequencies of loss or gains. Results The analysis of CNAs in cancers clearly demonstrates the existence of a significant pattern of loss of gene modules functionally related to cancer initiation and progression along with the amplification of modules of genes related to unspecific defense against xenobiotics (probably chemotherapeutical agents. With the extension of this analysis to an Array-CGH dataset (glioblastomas from The Cancer Genome Atlas we demonstrate the validity of this approach to investigate the functional impact of CNAs. Conclusions The presented results indicate promising clinical and therapeutic implications. Our findings also directly point out to the necessity of adopting a function-centric, rather a gene-centric, view in the understanding of phenotypes or diseases harboring CNAs.

  17. Three-Dimensional Interaction of a Large Number of Dense DEP Particles on a Plane Perpendicular to an AC Electrical Field

    Directory of Open Access Journals (Sweden)

    Chuanchuan Xie

    2017-01-01

    Full Text Available The interaction of dielectrophoresis (DEP particles in an electric field has been observed in many experiments, known as the “particle chains phenomenon”. However, the study in 3D models (spherical particles is rarely reported due to its complexity and significant computational cost. In this paper, we employed the iterative dipole moment (IDM method to study the 3D interaction of a large number of dense DEP particles randomly distributed on a plane perpendicular to a uniform alternating current (AC electric field in a bounded or unbounded space. The numerical results indicated that the particles cannot move out of the initial plane. The similar particles (either all positive or all negative DEP particles always repelled each other, and did not form a chain. The dissimilar particles (a mixture of positive and negative DEP particles always attracted each other, and formed particle chains consisting of alternately arranged positive and negative DEP particles. The particle chain patterns can be randomly multitudinous depending on the initial particle distribution, the electric properties of particles/fluid, the particle sizes and the number of particles. It is also found that the particle chain patterns can be effectively manipulated via tuning the frequency of the AC field and an almost uniform distribution of particles in a bounded plane chip can be achieved when all of the particles are similar, which may have potential applications in the particle manipulation of microfluidics.

  18. CD3+/CD16+CD56+ cell numbers in peripheral blood are correlated with higher tumor burden in patients with diffuse large B-cell lymphoma

    Directory of Open Access Journals (Sweden)

    Anna Twardosz

    2011-04-01

    Full Text Available Diffuse large B-cell lymphoma is the commonest histological type of malignant lymphoma, andremains incurable in many cases. Developing more efficient immunotherapy strategies will require betterunderstanding of the disorders of immune responses in cancer patients. NKT (natural killer-like T cells wereoriginally described as a unique population of T cells with the co-expression of NK cell markers. Apart fromtheir role in protecting against microbial pathogens and controlling autoimmune diseases, NKT cells havebeen recently revealed as one of the key players in the immune responses against tumors. The objective of thisstudy was to evaluate the frequency of CD3+/CD16+CD56+ cells in the peripheral blood of 28 diffuse largeB-cell lymphoma (DLBCL patients in correlation with clinical and laboratory parameters. Median percentagesof CD3+/CD16+CD56+ were significantly lower in patients with DLBCL compared to healthy donors(7.37% vs. 9.01%, p = 0.01; 4.60% vs. 5.81%, p = 0.03, although there were no differences in absolute counts.The frequency and the absolute numbers of CD3+/CD16+CD56+ cells were lower in advanced clinical stagesthan in earlier ones. The median percentage of CD3+/CD16+CD56+ cells in patients in Ann Arbor stages 1–2 was5.55% vs. 3.15% in stages 3–4 (p = 0.02, with median absolute counts respectively 0.26 G/L vs. 0.41 G/L (p == 0.02. The percentage and absolute numbers of CD3+/CD16+CD56+ cells were significantly higher in DL-BCL patients without B-symptoms compared to the patients with B-symptoms, (5.51% vs. 2.46%, p = 0.04;0.21 G/L vs. 0.44 G/L, p = 0.04. The percentage of CD3+/CD16+CD56+ cells correlated adversely with serumlactate dehydrogenase (R= –445; p < 0.05 which might influence NKT count. These figures suggest a relationshipbetween higher tumor burden and more aggressive disease and decreased NKT numbers. But it remains tobe explained whether low NKT cell counts in the peripheral blood of patients with DLBCL are the result

  19. Strong laws for L- and U-statistics

    NARCIS (Netherlands)

    Aaronson, J; Burton, R; Dehling, H; Gilat, D; Hill, T; Weiss, B

    Strong laws of large numbers are given for L-statistics (linear combinations of order statistics) and for U-statistics (averages of kernels of random samples) for ergodic stationary processes, extending classical theorems; of Hoeffding and of Helmers for lid sequences. Examples are given to show

  20. Successfully reducing newborn asphyxia in the labour unit in a large academic medical centre: a quality improvement project using statistical process control.

    Science.gov (United States)

    Hollesen, Rikke von Benzon; Johansen, Rie Laurine Rosenthal; Rørbye, Christina; Munk, Louise; Barker, Pierre; Kjaerbye-Thygesen, Anette

    2018-02-03

    A safe delivery is part of a good start in life, and a continuous focus on preventing harm during delivery is crucial, even in settings with a good safety record. In January 2013, the labour unit at Copenhagen University Hospital, Hvidovre, undertook a quality improvement (QI) project to prevent asphyxia and reduced the percentage of newborns with asphyxia by 48%. The change theory consisted of two primary elements: (1) the clinical content, including three clinical bundles of evidence-based care, a 'delivery bundle', an 'oxytocin bundle' and a 'vacuum extraction bundle'; (2) an implementation theory, including improving skills in interpretation of cardiotocography, use of QI methods and participation in a national learning network. The Model for Improvement and Deming's system of profound knowledge were used as a methodological framework. Data on compliance with the care bundles and the number of deliveries between newborns with asphyxia (Apgar statistical process control. Compliance with all three clinical care bundles improved to 95% or more, and the percentages of newborns with pH <7 and Apgar <7 after 5 min were reduced by 48% and 31%, respectively. In general, the QI approach strengthened multidisciplinary teamwork, systematised workflow and structured communication around the deliveries. Changes included making a standard memo in the medical record, the use of a bedside whiteboard, bedside handovers, shared decisions with a peer when using an oxytocin infusion and the use of a checklist before vacuum extractions. This QI project illustrates how aspects of patient safety, such as the prevention of asphyxia, can be improved using QI methods to more reliably implement best practice, even in high-performing systems. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  1. National transportation statistics 2010

    Science.gov (United States)

    2010-01-01

    National Transportation Statistics presents statistics on the U.S. transportation system, including its physical components, safety record, economic performance, the human and natural environment, and national security. This is a large online documen...

  2. Permutation statistical methods an integrated approach

    CERN Document Server

    Berry, Kenneth J; Johnston, Janis E

    2016-01-01

    This research monograph provides a synthesis of a number of statistical tests and measures, which, at first consideration, appear disjoint and unrelated. Numerous comparisons of permutation and classical statistical methods are presented, and the two methods are compared via probability values and, where appropriate, measures of effect size. Permutation statistical methods, compared to classical statistical methods, do not rely on theoretical distributions, avoid the usual assumptions of normality and homogeneity of variance, and depend only on the data at hand. This text takes a unique approach to explaining statistics by integrating a large variety of statistical methods, and establishing the rigor of a topic that to many may seem to be a nascent field in statistics. This topic is new in that it took modern computing power to make permutation methods available to people working in the mainstream of research. This research monograph addresses a statistically-informed audience, and can also easily serve as a ...

  3. Book Trade Research and Statistics. Prices of U.S. and Foreign Published Materials; Book Title Output and Average Prices: 2000 Final and 2001 Preliminary Figures; Book Sales Statistics, 2001: AAP Preliminary Estimates; U.S. Book Exports and Imports: 2001; Number of Book Outlets in the United States and Canada; Review Media Statistics.

    Science.gov (United States)

    Sullivan, Sharon G.; Barr, Catherine; Grabois, Andrew

    2002-01-01

    Includes six articles that report on prices of U.S. and foreign published materials; book title output and average prices; book sales statistics; book exports and imports; book outlets in the U.S. and Canada; and review media statistics. (LRW)

  4. Quiescent Galaxies in the 3D-HST Survey: Spectroscopic Confirmation of a Large Number of Galaxies with Relatively Old Stellar Populations at z ~ 2

    Science.gov (United States)

    Whitaker, Katherine E.; van Dokkum, Pieter G.; Brammer, Gabriel; Momcheva, Ivelina G.; Skelton, Rosalind; Franx, Marijn; Kriek, Mariska; Labbé, Ivo; Fumagalli, Mattia; Lundgren, Britt F.; Nelson, Erica J.; Patel, Shannon G.; Rix, Hans-Walter

    2013-06-01

    Quiescent galaxies at z ~ 2 have been identified in large numbers based on rest-frame colors, but only a small number of these galaxies have been spectroscopically confirmed to show that their rest-frame optical spectra show either strong Balmer or metal absorption lines. Here, we median stack the rest-frame optical spectra for 171 photometrically quiescent galaxies at 1.4 < z < 2.2 from the 3D-HST grism survey. In addition to Hβ (λ4861 Å), we unambiguously identify metal absorption lines in the stacked spectrum, including the G band (λ4304 Å), Mg I (λ5175 Å), and Na I (λ5894 Å). This finding demonstrates that galaxies with relatively old stellar populations already existed when the universe was ~3 Gyr old, and that rest-frame color selection techniques can efficiently select them. We find an average age of 1.3^{+0.1}_{-0.3} Gyr when fitting a simple stellar population to the entire stack. We confirm our previous result from medium-band photometry that the stellar age varies with the colors of quiescent galaxies: the reddest 80% of galaxies are dominated by metal lines and have a relatively old mean age of 1.6^{+0.5}_{-0.4} Gyr, whereas the bluest (and brightest) galaxies have strong Balmer lines and a spectroscopic age of 0.9^{+0.2}_{-0.1} Gyr. Although the spectrum is dominated by an evolved stellar population, we also find [O III] and Hβ emission. Interestingly, this emission is more centrally concentrated than the continuum with {L_{{O}\\,\\scriptsize{III}}}=1.7+/- 0.3\\times 10^{40} erg s-1, indicating residual central star formation or nuclear activity.

  5. Statistical thermodynamics

    International Nuclear Information System (INIS)

    Lim, Gyeong Hui

    2008-03-01

    This book consists of 15 chapters, which are basic conception and meaning of statistical thermodynamics, Maxwell-Boltzmann's statistics, ensemble, thermodynamics function and fluctuation, statistical dynamics with independent particle system, ideal molecular system, chemical equilibrium and chemical reaction rate in ideal gas mixture, classical statistical thermodynamics, ideal lattice model, lattice statistics and nonideal lattice model, imperfect gas theory on liquid, theory on solution, statistical thermodynamics of interface, statistical thermodynamics of a high molecule system and quantum statistics

  6. Identification of rare recurrent copy number variants in high-risk autism families and their prevalence in a large ASD population.

    Directory of Open Access Journals (Sweden)

    Nori Matsunami

    Full Text Available Structural variation is thought to play a major etiological role in the development of autism spectrum disorders (ASDs, and numerous studies documenting the relevance of copy number variants (CNVs in ASD have been published since 2006. To determine if large ASD families harbor high-impact CNVs that may have broader impact in the general ASD population, we used the Affymetrix genome-wide human SNP array 6.0 to identify 153 putative autism-specific CNVs present in 55 individuals with ASD from 9 multiplex ASD pedigrees. To evaluate the actual prevalence of these CNVs as well as 185 CNVs reportedly associated with ASD from published studies many of which are insufficiently powered, we designed a custom Illumina array and used it to interrogate these CNVs in 3,000 ASD cases and 6,000 controls. Additional single nucleotide variants (SNVs on the array identified 25 CNVs that we did not detect in our family studies at the standard SNP array resolution. After molecular validation, our results demonstrated that 15 CNVs identified in high-risk ASD families also were found in two or more ASD cases with odds ratios greater than 2.0, strengthening their support as ASD risk variants. In addition, of the 25 CNVs identified using SNV probes on our custom array, 9 also had odds ratios greater than 2.0, suggesting that these CNVs also are ASD risk variants. Eighteen of the validated CNVs have not been reported previously in individuals with ASD and three have only been observed once. Finally, we confirmed the association of 31 of 185 published ASD-associated CNVs in our dataset with odds ratios greater than 2.0, suggesting they may be of clinical relevance in the evaluation of children with ASDs. Taken together, these data provide strong support for the existence and application of high-impact CNVs in the clinical genetic evaluation of children with ASD.

  7. An introduction to statistical thermodynamics

    CERN Document Server

    Hill, Terrell L

    1987-01-01

    ""A large number of exercises of a broad range of difficulty make this book even more useful…a good addition to the literature on thermodynamics at the undergraduate level."" - Philosophical MagazineAlthough written on an introductory level, this wide-ranging text provides extensive coverage of topics of current interest in equilibrium statistical mechanics. Indeed, certain traditional topics are given somewhat condensed treatment to allow room for a survey of more recent advances.The book is divided into four major sections. Part I deals with the principles of quantum statistical mechanics a

  8. [The number of deaths by suicide after the Great East Japan Earthquake based on demographic statistics in the coastal and non-coastal areas of Iwate, Miyagi, and Fukushima prefectures].

    Science.gov (United States)

    Masaki, Naoko; Hashimoto, Shuji; Kawado, Miyuki; Ojima, Toshiyuki; Takeshima, Tadashi; Matsubara, Miyuki; Mitoku, Kazuko; Ogata, Yukiko

    2018-01-01

    Objective The number of deaths by suicide after the Great East Japan Earthquake was surveyed based on demographic statistics. In particular, this study examined whether or not there were excessive deaths due to suicide (excluding people who were injured in the earthquake) after the Great East Japan Earthquake disaster. This examination surveyed municipalities in coastal and non-coastal areas of Iwate, Miyagi, and Fukushima prefectures (referred to below as the "three prefectures").Methods The demographic statistics questionnaire survey information supplied by Article 33 of the Statistics Act (Ministry of Health, Labour and Welfare's published statistics Vol. 0925 No.4, September 25 th , 2014) were used as the basic data with particular reference to the information on the deaths from January 1 st , 2010 to March 31 st , 2013. The information obtained included the date of death, the municipality where the address of the deceased was registered, the gender of the deceased, age at the time of death, and cause of death codes (International Classification of Disease Codes 10 th revision: ICD-10). Additionally, information was gathered about the population based on the resident register from 2009 to 2013 and the 2010 National Census; the number of deaths by suicide was then totalled by period and area. The areas were classified as municipalities within three prefectures and those located elsewhere using the municipality where the address of the deceased was registered.Results The SMR for suicides did not show a tendency to increase for coastal or non-coastal areas throughout the two-year period after the earthquake disaster (from March 2011 to February 2013). The SMR for the three prefectures 0-1 years after the disaster compared with the year before the disaster was 0.92 and for 1-2 years after the disaster was 0.93. Both these values were significantly low. Looking at both the non-coastal and coastal areas from each of the three prefectures, the SMR for suicides

  9. On the calculation of line strengths, oscillator strengths and lifetimes for very large principal quantum numbers in hydrogenic atoms and ions by the McLean–Watson formula

    International Nuclear Information System (INIS)

    Hey, J D

    2014-01-01

    As a sequel to an earlier study (Hey 2009 J. Phys. B: At. Mol. Opt. Phys. 42 125701), we consider further the application of the line strength formula derived by Watson (2006 J. Phys. B: At. Mol. Opt. Phys. 39 L291) to transitions arising from states of very high principal quantum number in hydrogenic atoms and ions (Rydberg–Rydberg transitions, n > 1000). It is shown how apparent difficulties associated with the use of recurrence relations, derived (Hey 2006 J. Phys. B: At. Mol. Opt. Phys. 39 2641) by the ladder operator technique of Infeld and Hull (1951 Rev. Mod. Phys. 23 21), may be eliminated by a very simple numerical device, whereby this method may readily be applied up to n ≈ 10 000. Beyond this range, programming of the method may entail greater care and complexity. The use of the numerically efficient McLean–Watson formula for such cases is again illustrated by the determination of radiative lifetimes and comparison of present results with those from an asymptotic formula. The question of the influence on the results of the omission or inclusion of fine structure is considered by comparison with calculations based on the standard Condon–Shortley line strength formula. Interest in this work on the radial matrix elements for large n and n′ is related to measurements of radio recombination lines from tenuous space plasmas, e.g. Stepkin et al (2007 Mon. Not. R. Astron. Soc. 374 852), Bell et al (2011 Astrophys. Space Sci. 333 377), to the calculation of electron impact broadening parameters for such spectra (Watson 2006 J. Phys. B: At. Mol. Opt. Phys. 39 1889) and comparison with other theoretical methods (Peach 2014 Adv. Space Res. in press), to the modelling of physical processes in H II regions (Roshi et al 2012 Astrophys. J. 749 49), and the evaluation bound–bound transitions from states of high n during primordial cosmological recombination (Grin and Hirata 2010 Phys. Rev. D 81 083005, Ali-Haïmoud and Hirata 2010 Phys. Rev. D 82 063521

  10. Cancer Statistics

    Science.gov (United States)

    ... What Is Cancer? Cancer Statistics Cancer Disparities Cancer Statistics Cancer has a major impact on society in ... success of efforts to control and manage cancer. Statistics at a Glance: The Burden of Cancer in ...

  11. SVA retrotransposon insertion-associated deletion represents a novel mutational mechanism underlying large genomic copy number changes with non-recurrent breakpoints

    NARCIS (Netherlands)

    J. Vogt (Julia); K. Bengesser (Kathrin); K.B.M. Claes (Kathleen B.M.); K. Wimmer (Katharina); V.-F. Mautner (Victor-Felix); R. van Minkelen (Rick); E. Legius (Eric); H. Brems (Hilde); M. Upadhyaya (Meena); J. Högel (Josef); C. Lazaro (Conxi); T. Rosenbaum (Thorsten); S. Bammert (Simone); L. Messiaen (Ludwine); D.N. Cooper (David); H. Kehrer-Sawatzki (Hildegard)

    2014-01-01

    textabstractBackground: Genomic disorders are caused by copy number changes that may exhibit recurrent breakpoints processed by nonallelic homologous recombination. However, region-specific disease-associated copy number changes have also been observed which exhibit non-recurrent breakpoints. The

  12. Foundation of statistical energy analysis in vibroacoustics

    CERN Document Server

    Le Bot, A

    2015-01-01

    This title deals with the statistical theory of sound and vibration. The foundation of statistical energy analysis is presented in great detail. In the modal approach, an introduction to random vibration with application to complex systems having a large number of modes is provided. For the wave approach, the phenomena of propagation, group speed, and energy transport are extensively discussed. Particular emphasis is given to the emergence of diffuse field, the central concept of the theory.

  13. Rayleigh- and Prandtl-number dependence of the large-scale flow-structure in weakly-rotating turbulent thermal convection

    Science.gov (United States)

    Weiss, Stephan; Wei, Ping; Ahlers, Guenter

    2015-11-01

    Turbulent thermal convection under rotation shows a remarkable variety of different flow states. The Nusselt number (Nu) at slow rotation rates (expressed as the dimensionless inverse Rossby number 1/Ro), for example, is not a monotonic function of 1/Ro. Different 1/Ro-ranges can be observed with different slopes ∂Nu / ∂ (1 / Ro) . Some of these ranges are connected by sharp transitions where ∂Nu / ∂ (1 / Ro) changes discontinuously. We investigate different regimes in cylindrical samples of aspect ratio Γ = 1 by measuring temperatures at the sidewall of the sample for various Prandtl numbers in the range 3 Deutsche Forschungsgemeinschaft.

  14. Statistical Properties of Online Auctions

    Science.gov (United States)

    Namazi, Alireza; Schadschneider, Andreas

    We characterize the statistical properties of a large number of online auctions run on eBay. Both stationary and dynamic properties, like distributions of prices, number of bids etc., as well as relations between these quantities are studied. The analysis of the data reveals surprisingly simple distributions and relations, typically of power-law form. Based on these findings we introduce a simple method to identify suspicious auctions that could be influenced by a form of fraud known as shill bidding. Furthermore the influence of bidding strategies is discussed. The results indicate that the observed behavior is related to a mixture of agents using a variety of strategies.

  15. Statistical and theoretical research

    International Nuclear Information System (INIS)

    Anon.

    1983-01-01

    Significant accomplishments include the creation of field designs to detect population impacts, new census procedures for small mammals, and methods for designing studies to determine where and how much of a contaminant is extent over certain landscapes. A book describing these statistical methods is currently being written and will apply to a variety of environmental contaminants, including radionuclides. PNL scientists also have devised an analytical method for predicting the success of field eexperiments on wild populations. Two highlights of current research are the discoveries that population of free-roaming horse herds can double in four years and that grizzly bear populations may be substantially smaller than once thought. As stray horses become a public nuisance at DOE and other large Federal sites, it is important to determine their number. Similar statistical theory can be readily applied to other situations where wild animals are a problem of concern to other government agencies. Another book, on statistical aspects of radionuclide studies, is written specifically for researchers in radioecology

  16. Using Statistics and Data Mining Approaches to Analyze Male Sexual Behaviors and Use of Erectile Dysfunction Drugs Based on Large Questionnaire Data.

    Science.gov (United States)

    Qiao, Zhi; Li, Xiang; Liu, Haifeng; Zhang, Lei; Cao, Junyang; Xie, Guotong; Qin, Nan; Jiang, Hui; Lin, Haocheng

    2017-01-01

    The prevalence of erectile dysfunction (ED) has been extensively studied worldwide. Erectile dysfunction drugs has shown great efficacy in preventing male erectile dysfunction. In order to help doctors know drug taken preference of patients and better prescribe, it is crucial to analyze who actually take erectile dysfunction drugs and the relation between sexual behaviors and drug use. Existing clinical studies usually used descriptive statistics and regression analysis based on small volume of data. In this paper, based on big volume of data (48,630 questionnaires), we use data mining approaches besides statistics and regression analysis to comprehensively analyze the relation between male sexual behaviors and use of erectile dysfunction drugs for unravelling the characteristic of patients who take erectile dysfunction drugs. We firstly analyze the impact of multiple sexual behavior factors on whether to use the erectile dysfunction drugs. Then, we explore to mine the Decision Rules for Stratification to discover patients who are more likely to take drugs. Based on the decision rules, the patients can be partitioned into four potential groups for use of erectile dysfunction: high potential group, intermediate potential-1 group, intermediate potential-2 group and low potential group. Experimental results show 1) the sexual behavior factors, erectile hardness and time length to prepare (how long to prepares for sexual behaviors ahead of time), have bigger impacts both in correlation analysis and potential drug taking patients discovering; 2) odds ratio between patients identified as low potential and high potential was 6.098 (95% confidence interval, 5.159-7.209) with statistically significant differences in taking drug potential detected between all potential groups.

  17. A statistical methodology to derive the scaling law for the H-mode power threshold using a large multi-machine database

    International Nuclear Information System (INIS)

    Murari, A.; Lupelli, I.; Gaudio, P.; Gelfusa, M.; Vega, J.

    2012-01-01

    In this paper, a refined set of statistical techniques is developed and then applied to the problem of deriving the scaling law for the threshold power to access the H-mode of confinement in tokamaks. This statistical methodology is applied to the 2010 version of the ITPA International Global Threshold Data Base v6b(IGDBTHv6b). To increase the engineering and operative relevance of the results, only macroscopic physical quantities, measured in the vast majority of experiments, have been considered as candidate variables in the models. Different principled methods, such as agglomerative hierarchical variables clustering, without assumption about the functional form of the scaling, and nonlinear regression, are implemented to select the best subset of candidate independent variables and to improve the regression model accuracy. Two independent model selection criteria, based on the classical (Akaike information criterion) and Bayesian formalism (Bayesian information criterion), are then used to identify the most efficient scaling law from candidate models. The results derived from the full multi-machine database confirm the results of previous analysis but emphasize the importance of shaping quantities, elongation and triangularity. On the other hand, the scaling laws for the different machines and at different currents are different from each other at the level of confidence well above 95%, suggesting caution in the use of the global scaling laws for both interpretation and extrapolation purposes. (paper)

  18. Development of special machines for production of large number of superconducting coils for the spool correctors for the main dipole of LHC

    International Nuclear Information System (INIS)

    Puntambekar, A.M.; Karmarkar, M.G.

    2003-01-01

    Superconducting (Sc) spool correctors of different types namely Sextupole, (MCS) Decapole (MCD) and Octupole (MCO) are incorporated in each of the main dipole of Large Hadron Collider (LHC). In all 2464 MCS and 1232 MCDO magnets are required to equip all 1232 Dipoles of LHC. The coils wound from thin rectangular section Sc wires are the heart of magnet assembly and its performance for the field quality and cold quench training largely depends on the precise and robust construction of these coils. Under DAE-CERN collaboration CAT was entrusted with the responsibility of making these magnets for LHC. Starting with development of manual fixtures and prototyping using soldering, a more advances special Automatic Coils Winding and Ultrasonic Welding (USW) system for production of large no. of coils and magnets were built at CAT. The paper briefly describes the various developments in this area. (author)

  19. Experimental observations of electron-backscatter effects from high-atomic-number anodes in large-aspect-ratio, electron-beam diodes

    Energy Technology Data Exchange (ETDEWEB)

    Cooperstein, G; Mosher, D; Stephanakis, S J; Weber, B V; Young, F C [Naval Research Laboratory, Washington, DC (United States); Swanekamp, S B [JAYCOR, Vienna, VA (United States)

    1997-12-31

    Backscattered electrons from anodes with high-atomic-number substrates cause early-time anode-plasma formation from the surface layer leading to faster, more intense electron beam pinching, and lower diode impedance. A simple derivation of Child-Langmuir current from a thin hollow cathode shows the same dependence on the diode aspect ratio as critical current. Using this fact, it is shown that the diode voltage and current follow relativistic Child-Langmuir theory until the anode plasma is formed, and then follows critical current after the beam pinches. With thin hollow cathodes, electron beam pinching can be suppressed at low voltages (< 800 kV) even for high currents and high-atomic-number anodes. Electron beam pinching can also be suppressed at high voltages for low-atomic-number anodes as long as the electron current densities remain below the plasma turn-on threshold. (author). 8 figs., 2 refs.

  20. Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release

    DEFF Research Database (Denmark)

    Hansen, S K; Gjesing, A P; Rasmussen, S K

    2004-01-01

    The class III allele of the variable-number-of-tandem-repeats polymorphism located 5' of the insulin gene (INS-VNTR) has been associated with Type 2 diabetes and altered birthweight. It has also been suggested, although inconsistently, that the class III allele plays a role in glucose-induced ins......The class III allele of the variable-number-of-tandem-repeats polymorphism located 5' of the insulin gene (INS-VNTR) has been associated with Type 2 diabetes and altered birthweight. It has also been suggested, although inconsistently, that the class III allele plays a role in glucose...

  1. Statistical mechanics and the foundations of thermodynamics

    International Nuclear Information System (INIS)

    Loef, A.M.

    1979-01-01

    An introduction to classical statistical mechanics and its relation to thermodynamics is presented. Emphasis is put on getting a detailed and logical presentation of the foundations of thermodynamics based on the maximum entropy principles which govern the values taken by macroscopic variables according to the laws of large numbers

  2. Planning Alternative Organizational Frameworks For a Large Scale Educational Telecommunications System Served by Fixed/Broadcast Satellites. Memorandum Number 73/3.

    Science.gov (United States)

    Walkmeyer, John

    Considerations relating to the design of organizational structures for development and control of large scale educational telecommunications systems using satellites are explored. The first part of the document deals with four issues of system-wide concern. The first is user accessibility to the system, including proximity to entry points, ability…

  3. The number of extranodal sites assessed by PET/CT scan is a powerful predictor of CNS relapse for patients with diffuse large B-cell lymphoma

    DEFF Research Database (Denmark)

    El-Galaly, Tarec Christoffer; Villa, Diego; Michaelsen, Thomas Yssing

    2017-01-01

    Purpose Development of secondary central nervous system involvement (SCNS) in patients with diffuse large B-cell lymphoma is associated with poor outcomes. The CNS International Prognostic Index (CNS-IPI) has been proposed for identifying patients at greatest risk, but the optimal model is unknow...

  4. Handling large numbers of observation units in three-way methods for the analysis of qualitative and quantitative two-way data

    NARCIS (Netherlands)

    Kiers, Henk A.L.; Marchetti, G.M.

    1994-01-01

    Recently, a number of methods have been proposed for the exploratory analysis of mixtures of qualitative and quantitative variables. In these methods for each variable an object by object similarity matrix is constructed, and these are consequently analyzed by means of three-way methods like

  5. A large increase of sour taste receptor cells in Skn-1-deficient mice does not alter the number of their sour taste signal-transmitting gustatory neurons.

    Science.gov (United States)

    Maeda, Naohiro; Narukawa, Masataka; Ishimaru, Yoshiro; Yamamoto, Kurumi; Misaka, Takumi; Abe, Keiko

    2017-05-01

    The connections between taste receptor cells (TRCs) and innervating gustatory neurons are formed in a mutually dependent manner during development. To investigate whether a change in the ratio of cell types that compose taste buds influences the number of innervating gustatory neurons, we analyzed the proportion of gustatory neurons that transmit sour taste signals in adult Skn-1a -/- mice in which the number of sour TRCs is greatly increased. We generated polycystic kidney disease 1 like 3-wheat germ agglutinin (pkd1l3-WGA)/Skn-1a +/+ and pkd1l3-WGA/Skn-1a -/- mice by crossing Skn-1a -/- mice and pkd1l3-WGA transgenic mice, in which neural pathways of sour taste signals can be visualized. The number of WGA-positive cells in the circumvallate papillae is 3-fold higher in taste buds of pkd1l3-WGA/Skn-1a -/- mice relative to pkd1l3-WGA/Skn-1a +/+ mice. Intriguingly, the ratio of WGA-positive neurons to P2X 2 -expressing gustatory neurons in nodose/petrosal ganglia was similar between pkd1l3-WGA/Skn-1a +/+ and pkd1l3-WGA/Skn-1a -/- mice. In conclusion, an alteration in the ratio of cell types that compose taste buds does not influence the number of gustatory neurons that transmit sour taste signals. Copyright © 2017. Published by Elsevier B.V.

  6. The modified signed likelihood statistic and saddlepoint approximations

    DEFF Research Database (Denmark)

    Jensen, Jens Ledet

    1992-01-01

    SUMMARY: For a number of tests in exponential families we show that the use of a normal approximation to the modified signed likelihood ratio statistic r * is equivalent to the use of a saddlepoint approximation. This is also true in a large deviation region where the signed likelihood ratio...... statistic r is of order √ n. © 1992 Biometrika Trust....

  7. Usage Statistics

    Science.gov (United States)

    ... this page: https://medlineplus.gov/usestatistics.html MedlinePlus Statistics To use the sharing features on this page, ... By Quarter View image full size Quarterly User Statistics Quarter Page Views Unique Visitors Oct-Dec-98 ...

  8. An intercomparison of a large ensemble of statistical downscaling methods for Europe: Overall results from the VALUE perfect predictor cross-validation experiment

    Science.gov (United States)

    Gutiérrez, Jose Manuel; Maraun, Douglas; Widmann, Martin; Huth, Radan; Hertig, Elke; Benestad, Rasmus; Roessler, Ole; Wibig, Joanna; Wilcke, Renate; Kotlarski, Sven

    2016-04-01

    VALUE is an open European network to validate and compare downscaling methods for climate change research (http://www.value-cost.eu). A key deliverable of VALUE is the development of a systematic validation framework to enable the assessment and comparison of both dynamical and statistical downscaling methods. This framework is based on a user-focused validation tree, guiding the selection of relevant validation indices and performance measures for different aspects of the validation (marginal, temporal, spatial, multi-variable). Moreover, several experiments have been designed to isolate specific points in the downscaling procedure where problems may occur (assessment of intrinsic performance, effect of errors inherited from the global models, effect of non-stationarity, etc.). The list of downscaling experiments includes 1) cross-validation with perfect predictors, 2) GCM predictors -aligned with EURO-CORDEX experiment- and 3) pseudo reality predictors (see Maraun et al. 2015, Earth's Future, 3, doi:10.1002/2014EF000259, for more details). The results of these experiments are gathered, validated and publicly distributed through the VALUE validation portal, allowing for a comprehensive community-open downscaling intercomparison study. In this contribution we describe the overall results from Experiment 1), consisting of a European wide 5-fold cross-validation (with consecutive 6-year periods from 1979 to 2008) using predictors from ERA-Interim to downscale precipitation and temperatures (minimum and maximum) over a set of 86 ECA&D stations representative of the main geographical and climatic regions in Europe. As a result of the open call for contribution to this experiment (closed in Dec. 2015), over 40 methods representative of the main approaches (MOS and Perfect Prognosis, PP) and techniques (linear scaling, quantile mapping, analogs, weather typing, linear and generalized regression, weather generators, etc.) were submitted, including information both data

  9. Mathematical statistics

    CERN Document Server

    Pestman, Wiebe R

    2009-01-01

    This textbook provides a broad and solid introduction to mathematical statistics, including the classical subjects hypothesis testing, normal regression analysis, and normal analysis of variance. In addition, non-parametric statistics and vectorial statistics are considered, as well as applications of stochastic analysis in modern statistics, e.g., Kolmogorov-Smirnov testing, smoothing techniques, robustness and density estimation. For students with some elementary mathematical background. With many exercises. Prerequisites from measure theory and linear algebra are presented.

  10. Forty-Five-Year Mortality Rate as a Function of the Number and Type of Psychiatric Diagnoses Found in a Large Danish Birth Cohort

    DEFF Research Database (Denmark)

    Madarasz, Wendy; Manzardo, Ann; Mortensen, Erik Lykke

    2012-01-01

    Central Psychiatric Research Registry for 8109 birth cohort members aged 45 years. Lifetime psychiatric diagnoses (International Classification of Diseases, Revision 10, group F codes, Mental and Behavioural Disorders, and one Z code) for identified subjects were organized into 14 mutually exclusive......Objective: Psychiatric comorbidities are common among psychiatric patients and typically associated with poorer clinical prognoses. Subjects of a large Danish birth cohort were used to study the relation between mortality and co-occurring psychiatric diagnoses. Method: We searched the Danish...

  11. Load Frequency Control by use of a Number of Both Heat Pump Water Heaters and Electric Vehicles in Power System with a Large Integration of Renewable Energy Sources

    Science.gov (United States)

    Masuta, Taisuke; Shimizu, Koichiro; Yokoyama, Akihiko

    In Japan, from the viewpoints of global warming countermeasures and energy security, it is expected to establish a smart grid as a power system into which a large amount of generation from renewable energy sources such as wind power generation and photovoltaic generation can be installed. Measures for the power system stability and reliability are necessary because a large integration of these renewable energy sources causes some problems in power systems, e.g. frequency fluctuation and distribution voltage rise, and Battery Energy Storage System (BESS) is one of effective solutions to these problems. Due to a high cost of the BESS, our research group has studied an application of controllable loads such as Heat Pump Water Heater (HPWH) and Electric Vehicle (EV) to the power system control for reduction of the required capacity of BESS. This paper proposes a new coordinated Load Frequency Control (LFC) method for the conventional power plants, the BESS, the HPWHs, and the EVs. The performance of the proposed LFC method is evaluated by the numerical simulations conducted on a power system model with a large integration of wind power generation and photovoltaic generation.

  12. Frog Statistics

    Science.gov (United States)

    Whole Frog Project and Virtual Frog Dissection Statistics wwwstats output for January 1 through duplicate or extraneous accesses. For example, in these statistics, while a POST requesting an image is as well. Note that this under-represents the bytes requested. Starting date for following statistics

  13. Reconstructing Macroeconomics Based on Statistical Physics

    Science.gov (United States)

    Aoki, Masanao; Yoshikawa, Hiroshi

    We believe that time has come to integrate the new approach based on statistical physics or econophysics into macroeconomics. Toward this goal, there must be more dialogues between physicists and economists. In this paper, we argue that there is no reason why the methods of statistical physics so successful in many fields of natural sciences cannot be usefully applied to macroeconomics that is meant to analyze the macroeconomy comprising a large number of economic agents. It is, in fact, weird to regard the macroeconomy as a homothetic enlargement of the representative micro agent. We trust the bright future of the new approach to macroeconomies based on statistical physics.

  14. A robust variant of block Jacobi-Davidson for extracting a large number of eigenpairs: Application to grid-based real-space density functional theory

    Science.gov (United States)

    Lee, M.; Leiter, K.; Eisner, C.; Breuer, A.; Wang, X.

    2017-09-01

    In this work, we investigate a block Jacobi-Davidson (J-D) variant suitable for sparse symmetric eigenproblems where a substantial number of extremal eigenvalues are desired (e.g., ground-state real-space quantum chemistry). Most J-D algorithm variations tend to slow down as the number of desired eigenpairs increases due to frequent orthogonalization against a growing list of solved eigenvectors. In our specification of block J-D, all of the steps of the algorithm are performed in clusters, including the linear solves, which allows us to greatly reduce computational effort with blocked matrix-vector multiplies. In addition, we move orthogonalization against locked eigenvectors and working eigenvectors outside of the inner loop but retain the single Ritz vector projection corresponding to the index of the correction vector. Furthermore, we minimize the computational effort by constraining the working subspace to the current vectors being updated and the latest set of corresponding correction vectors. Finally, we incorporate accuracy thresholds based on the precision required by the Fermi-Dirac distribution. The net result is a significant reduction in the computational effort against most previous block J-D implementations, especially as the number of wanted eigenpairs grows. We compare our approach with another robust implementation of block J-D (JDQMR) and the state-of-the-art Chebyshev filter subspace (CheFSI) method for various real-space density functional theory systems. Versus CheFSI, for first-row elements, our method yields competitive timings for valence-only systems and 4-6× speedups for all-electron systems with up to 10× reduced matrix-vector multiplies. For all-electron calculations on larger elements (e.g., gold) where the wanted spectrum is quite narrow compared to the full spectrum, we observe 60× speedup with 200× fewer matrix-vector multiples vs. CheFSI.

  15. A development of the Gibbs potential of a quantised system made up of a large number of particles. III. The contribution of binary collisions

    International Nuclear Information System (INIS)

    BLOCH, Claude; DE DOMINICIS, Cyrano

    1959-01-01

    Starting from an expansion derived in a previous work, we study the contribution to the Gibbs potential of the two-body dynamical correlations, taking into account the statistical correlations. Such a contribution is of interest for low-density systems at low temperature. In the zero density limit, it reduces to the Beth-Uhlenbeck expression for the second virial coefficient. For a system of fermions in the zero temperature limit, it yields the contribution of the Brueckner reaction matrix to the ground state energy, plus, under certain conditions, additional terms of the form exp ( β / Δ /), where the Δ are the binding energies of 'bound states' of the type first discussed by L. Cooper. Finally, we study the wave function of two particles immersed in a medium (defined by its temperature and chemical potential). It satisfies an equation generalizing the Bethe-Goldstone equation for an arbitrary temperature. Reprint of a paper published in Nuclear Physics, 10, p. 509-526, 1959

  16. Modelling of natural convection flows with large temperature differences: a benchmark problem for low Mach number solvers. Part. 1 reference solutions

    International Nuclear Information System (INIS)

    Le Quere, P.; Weisman, C.; Paillere, H.; Vierendeels, J.; Dick, E.; Becker, R.; Braack, M.; Locke, J.

    2005-01-01

    Heat transfer by natural convection and conduction in enclosures occurs in numerous practical situations including the cooling of nuclear reactors. For large temperature difference, the flow becomes compressible with a strong coupling between the continuity, the momentum and the energy equations through the equation of state, and its properties (viscosity, heat conductivity) also vary with the temperature, making the Boussinesq flow approximation inappropriate and inaccurate. There are very few reference solutions in the literature on non-Boussinesq natural convection flows. We propose here a test case problem which extends the well-known De Vahl Davis differentially heated square cavity problem to the case of large temperature differences for which the Boussinesq approximation is no longer valid. The paper is split in two parts: in this first part, we propose as yet unpublished reference solutions for cases characterized by a non-dimensional temperature difference of 0.6, Ra 10 6 (constant property and variable property cases) and Ra = 10 7 (variable property case). These reference solutions were produced after a first international workshop organized by Cea and LIMSI in January 2000, in which the above authors volunteered to produce accurate numerical solutions from which the present reference solutions could be established. (authors)

  17. Prediction of the number of 14 MeV neutron elastically scattered from large sample of aluminium using Monte Carlo simulation method

    International Nuclear Information System (INIS)

    Husin Wagiran; Wan Mohd Nasir Wan Kadir

    1997-01-01

    In neutron scattering processes, the effect of multiple scattering is to cause an effective increase in the measured cross-sections due to increase on the probability of neutron scattering interactions in the sample. Analysis of how the effective cross-section varies with thickness is very complicated due to complicated sample geometries and the variations of scattering cross-section with energy. Monte Carlo method is one of the possible method for treating the multiple scattering processes in the extended sample. In this method a lot of approximations have to be made and the accurate data of microscopic cross-sections are needed at various angles. In the present work, a Monte Carlo simulation programme suitable for a small computer was developed. The programme was capable to predict the number of neutrons scattered from various thickness of aluminium samples at all possible angles between 00 to 36011 with 100 increments. In order to make the the programme not too complicated and capable of being run on microcomputer with reasonable time, the calculations was done in two dimension coordinate system. The number of neutrons predicted from this model show in good agreement with previous experimental results

  18. Implementation of genomic recursions in single-step genomic best linear unbiased predictor for US Holsteins with a large number of genotyped animals.

    Science.gov (United States)

    Masuda, Y; Misztal, I; Tsuruta, S; Legarra, A; Aguilar, I; Lourenco, D A L; Fragomeni, B O; Lawlor, T J

    2016-03-01

    The objectives of this study were to develop and evaluate an efficient implementation in the computation of the inverse of genomic relationship matrix with the recursion algorithm, called the algorithm for proven and young (APY), in single-step genomic BLUP. We validated genomic predictions for young bulls with more than 500,000 genotyped animals in final score for US Holsteins. Phenotypic data included 11,626,576 final scores on 7,093,380 US Holstein cows, and genotypes were available for 569,404 animals. Daughter deviations for young bulls with no classified daughters in 2009, but at least 30 classified daughters in 2014 were computed using all the phenotypic data. Genomic predictions for the same bulls were calculated with single-step genomic BLUP using phenotypes up to 2009. We calculated the inverse of the genomic relationship matrix GAPY(-1) based on a direct inversion of genomic relationship matrix on a small subset of genotyped animals (core animals) and extended that information to noncore animals by recursion. We tested several sets of core animals including 9,406 bulls with at least 1 classified daughter, 9,406 bulls and 1,052 classified dams of bulls, 9,406 bulls and 7,422 classified cows, and random samples of 5,000 to 30,000 animals. Validation reliability was assessed by the coefficient of determination from regression of daughter deviation on genomic predictions for the predicted young bulls. The reliabilities were 0.39 with 5,000 randomly chosen core animals, 0.45 with the 9,406 bulls, and 7,422 cows as core animals, and 0.44 with the remaining sets. With phenotypes truncated in 2009 and the preconditioned conjugate gradient to solve mixed model equations, the number of rounds to convergence for core animals defined by bulls was 1,343; defined by bulls and cows, 2,066; and defined by 10,000 random animals, at most 1,629. With complete phenotype data, the number of rounds decreased to 858, 1,299, and at most 1,092, respectively. Setting up GAPY(-1

  19. VA PTSD Statistics

    Data.gov (United States)

    Department of Veterans Affairs — National-level, VISN-level, and/or VAMC-level statistics on the numbers and percentages of users of VHA care form the Northeast Program Evaluation Center (NEPEC)....

  20. Fractional statistics and fractional quantized Hall effect. Revision

    International Nuclear Information System (INIS)

    Tao, R.; Wu, Y.S.

    1984-01-01

    We suggest that the origin of the odd denominator rule observed in the fractional quantized Hall effect (FQHE) may lie in fractional statistics which governs quasiparticles in FQHE. A theorem concerning statistics of clusters of quasiparticles implies that fractional statistics does not allow coexistence of a large number of quasiparticles at fillings with an even denominator. Thus no Hall plateau can be formed at these fillings, regardless of the presence of an energy gap. 15 references

  1. A modification to linearized theory for prediction of pressure loadings on lifting surfaces at high supersonic Mach numbers and large angles of attack

    Science.gov (United States)

    Carlson, H. W.

    1979-01-01

    A new linearized-theory pressure-coefficient formulation was studied. The new formulation is intended to provide more accurate estimates of detailed pressure loadings for improved stability analysis and for analysis of critical structural design conditions. The approach is based on the use of oblique-shock and Prandtl-Meyer expansion relationships for accurate representation of the variation of pressures with surface slopes in two-dimensional flow and linearized-theory perturbation velocities for evaluation of local three-dimensional aerodynamic interference effects. The applicability and limitations of the modification to linearized theory are illustrated through comparisons with experimental pressure distributions for delta wings covering a Mach number range from 1.45 to 4.60 and angles of attack from 0 to 25 degrees.

  2. High Frequency Design Considerations for the Large Detector Number and Small Form Factor Dual Electron Spectrometer of the Fast Plasma Investigation on NASA's Magnetospheric Multiscale Mission

    Science.gov (United States)

    Kujawski, Joseph T.; Gliese, Ulrik B.; Cao, N. T.; Zeuch, M. A.; White, D.; Chornay, D. J; Lobell, J. V.; Avanov, L. A.; Barrie, A. C.; Mariano, A. J.; hide

    2015-01-01

    Each half of the Dual Electron Spectrometer (DES) of the Fast Plasma Investigation (FPI) on NASA's Magnetospheric MultiScale (MMS) mission utilizes a microchannel plate Chevron stack feeding 16 separate detection channels each with a dedicated anode and amplifier/discriminator chip. The desire to detect events on a single channel with a temporal spacing of 100 ns and a fixed dead-time drove our decision to use an amplifier/discriminator with a very fast (GHz class) front end. Since the inherent frequency response of each pulse in the output of the DES microchannel plate system also has frequency components above a GHz, this produced a number of design constraints not normally expected in electronic systems operating at peak speeds of 10 MHz. Additional constraints are imposed by the geometry of the instrument requiring all 16 channels along with each anode and amplifier/discriminator to be packaged in a relatively small space. We developed an electrical model for board level interactions between the detector channels to allow us to design a board topology which gave us the best detection sensitivity and lowest channel to channel crosstalk. The amplifier/discriminator output was designed to prevent the outputs from one channel from producing triggers on the inputs of other channels. A number of Radio Frequency design techniques were then applied to prevent signals from other subsystems (e.g. the high voltage power supply, command and data handling board, and Ultraviolet stimulation for the MCP) from generating false events. These techniques enabled us to operate the board at its highest sensitivity when operated in isolation and at very high sensitivity when placed into the overall system.

  3. Statistical physics

    CERN Document Server

    Sadovskii, Michael V

    2012-01-01

    This volume provides a compact presentation of modern statistical physics at an advanced level. Beginning with questions on the foundations of statistical mechanics all important aspects of statistical physics are included, such as applications to ideal gases, the theory of quantum liquids and superconductivity and the modern theory of critical phenomena. Beyond that attention is given to new approaches, such as quantum field theory methods and non-equilibrium problems.

  4. Emissions from waste combustion. An application of statistical experimental design in a laboratory-scale boiler and an investigation from large-scale incineration plants

    Energy Technology Data Exchange (ETDEWEB)

    Xiaojing, Zhang

    1997-05-01

    The aim of this thesis is a study of the emissions from the combustion of household refuse. The experiments were both on a laboratory-scale boiler and on full-scale incineration plants. In the laboratory, an artificial household refuse with known composition was fed into a pilot boiler with a stationary grate. Combustion was under non-optimum conditions. Direct sampling with a Tenax adsorbent was used to measure a range of VOCs. Measurements were also made of incompletely burnt hydrocarbons, carbon monoxide, carbon dioxide, oxygen and flue gas temperature. Combustion and emission parameters were recorded continuously by a multi-point data logger. VOCs were analysed by gas chromatography and mass spectrometry (GC/MS). The full-scale tests were on seven Swedish incineration plants. The data were used to evaluate the emissions from large-scale incineration plants with various type of fuels and incinerators, and were also compared with the laboratory results. The response surface model developed from the laboratory experiments was also validated. This thesis also includes studies on the gasification of household refuse pellets, estimations of particulate and soot emissions, and a thermodynamic analysis of PAHs from combustion flue gas. For pellet gasification, experiments were performed on single, well characterised refuse pellets under carefully controlled conditions. The aim was to see if the effects of pellets were different from those of untreated household refuse. The results from both laboratory and full-scale tests showed that the main contributions to emissions from household refuse are plastics and moisture. 142 refs, 82 figs, 51 tabs

  5. Large Diversity of Porcine Yersinia enterocolitica 4/O:3 in Eight European Countries Assessed by Multiple-Locus Variable-Number Tandem-Repeat Analysis.

    Science.gov (United States)

    Alakurtti, Sini; Keto-Timonen, Riikka; Virtanen, Sonja; Martínez, Pilar Ortiz; Laukkanen-Ninios, Riikka; Korkeala, Hannu

    2016-06-01

    A total of 253 multiple-locus variable-number tandem-repeat analysis (MLVA) types among 634 isolates were discovered while studying the genetic diversity of porcine Yersinia enterocolitica 4/O:3 isolates from eight different European countries. Six variable-number tandem-repeat (VNTR) loci V2A, V4, V5, V6, V7, and V9 were used to study the isolates from 82 farms in Belgium (n = 93, 7 farms), England (n = 41, 8 farms), Estonia (n = 106, 12 farms), Finland (n = 70, 13 farms), Italy (n = 111, 20 farms), Latvia (n = 66, 3 farms), Russia (n = 60, 10 farms), and Spain (n = 87, 9 farms). Cluster analysis revealed mainly country-specific clusters, and only one MLVA type consisting of two isolates was found from two countries: Russia and Italy. Also, farm-specific clusters were discovered, but same MLVA types could also be found from different farms. Analysis of multiple isolates originating either from the same tonsils (n = 4) or from the same farm, but 6 months apart, revealed both identical and different MLVA types. MLVA showed a very good discriminatory ability with a Simpson's discriminatory index (DI) of 0.989. DIs for VNTR loci V2A, V4, V5, V6, V7, and V9 were 0.916, 0.791, 0.901, 0.877, 0.912, and 0.785, respectively, when studying all isolates together, but variation was evident between isolates originating from different countries. Locus V4 in the Spanish isolates and locus V9 in the Latvian isolates did not differentiate (DI 0.000), and locus V9 in the English isolates showed very low discriminatory power (DI 0.049). The porcine Y. enterocolitica 4/O:3 isolates were diverse, but the variation in DI demonstrates that the well discriminating loci V2A, V5, V6, and V7 should be included in MLVA protocol when maximal discriminatory power is needed.

  6. Statistical optics

    CERN Document Server

    Goodman, Joseph W

    2015-01-01

    This book discusses statistical methods that are useful for treating problems in modern optics, and the application of these methods to solving a variety of such problems This book covers a variety of statistical problems in optics, including both theory and applications.  The text covers the necessary background in statistics, statistical properties of light waves of various types, the theory of partial coherence and its applications, imaging with partially coherent light, atmospheric degradations of images, and noise limitations in the detection of light. New topics have been introduced i

  7. Harmonic statistics

    Energy Technology Data Exchange (ETDEWEB)

    Eliazar, Iddo, E-mail: eliazar@post.tau.ac.il

    2017-05-15

    The exponential, the normal, and the Poisson statistical laws are of major importance due to their universality. Harmonic statistics are as universal as the three aforementioned laws, but yet they fall short in their ‘public relations’ for the following reason: the full scope of harmonic statistics cannot be described in terms of a statistical law. In this paper we describe harmonic statistics, in their full scope, via an object termed harmonic Poisson process: a Poisson process, over the positive half-line, with a harmonic intensity. The paper reviews the harmonic Poisson process, investigates its properties, and presents the connections of this object to an assortment of topics: uniform statistics, scale invariance, random multiplicative perturbations, Pareto and inverse-Pareto statistics, exponential growth and exponential decay, power-law renormalization, convergence and domains of attraction, the Langevin equation, diffusions, Benford’s law, and 1/f noise. - Highlights: • Harmonic statistics are described and reviewed in detail. • Connections to various statistical laws are established. • Connections to perturbation, renormalization and dynamics are established.

  8. Harmonic statistics

    International Nuclear Information System (INIS)

    Eliazar, Iddo

    2017-01-01

    The exponential, the normal, and the Poisson statistical laws are of major importance due to their universality. Harmonic statistics are as universal as the three aforementioned laws, but yet they fall short in their ‘public relations’ for the following reason: the full scope of harmonic statistics cannot be described in terms of a statistical law. In this paper we describe harmonic statistics, in their full scope, via an object termed harmonic Poisson process: a Poisson process, over the positive half-line, with a harmonic intensity. The paper reviews the harmonic Poisson process, investigates its properties, and presents the connections of this object to an assortment of topics: uniform statistics, scale invariance, random multiplicative perturbations, Pareto and inverse-Pareto statistics, exponential growth and exponential decay, power-law renormalization, convergence and domains of attraction, the Langevin equation, diffusions, Benford’s law, and 1/f noise. - Highlights: • Harmonic statistics are described and reviewed in detail. • Connections to various statistical laws are established. • Connections to perturbation, renormalization and dynamics are established.

  9. Statistical methods

    CERN Document Server

    Szulc, Stefan

    1965-01-01

    Statistical Methods provides a discussion of the principles of the organization and technique of research, with emphasis on its application to the problems in social statistics. This book discusses branch statistics, which aims to develop practical ways of collecting and processing numerical data and to adapt general statistical methods to the objectives in a given field.Organized into five parts encompassing 22 chapters, this book begins with an overview of how to organize the collection of such information on individual units, primarily as accomplished by government agencies. This text then

  10. Histoplasmosis Statistics

    Science.gov (United States)

    ... Testing Treatment & Outcomes Health Professionals Statistics More Resources Candidiasis Candida infections of the mouth, throat, and esophagus Vaginal candidiasis Invasive candidiasis Definition Symptoms Risk & Prevention Sources Diagnosis ...

  11. An Entropy-Based Statistic for Genomewide Association Studies

    OpenAIRE

    Zhao, Jinying; Boerwinkle, Eric; Xiong, Momiao

    2005-01-01

    Efficient genotyping methods and the availability of a large collection of single-nucleotide polymorphisms provide valuable tools for genetic studies of human disease. The standard χ2 statistic for case-control studies, which uses a linear function of allele frequencies, has limited power when the number of marker loci is large. We introduce a novel test statistic for genetic association studies that uses Shannon entropy and a nonlinear function of allele frequencies to amplify the difference...

  12. The One-carbon Carrier Methylofuran from Methylobacterium extorquens AM1 Contains a Large Number of α- and γ-Linked Glutamic Acid Residues*

    Science.gov (United States)

    Hemmann, Jethro L.; Saurel, Olivier; Ochsner, Andrea M.; Stodden, Barbara K.; Kiefer, Patrick; Milon, Alain; Vorholt, Julia A.

    2016-01-01

    Methylobacterium extorquens AM1 uses dedicated cofactors for one-carbon unit conversion. Based on the sequence identities of enzymes and activity determinations, a methanofuran analog was proposed to be involved in formaldehyde oxidation in Alphaproteobacteria. Here, we report the structure of the cofactor, which we termed methylofuran. Using an in vitro enzyme assay and LC-MS, methylofuran was identified in cell extracts and further purified. From the exact mass and MS-MS fragmentation pattern, the structure of the cofactor was determined to consist of a polyglutamic acid side chain linked to a core structure similar to the one present in archaeal methanofuran variants. NMR analyses showed that the core structure contains a furan ring. However, instead of the tyramine moiety that is present in methanofuran cofactors, a tyrosine residue is present in methylofuran, which was further confirmed by MS through the incorporation of a 13C-labeled precursor. Methylofuran was present as a mixture of different species with varying numbers of glutamic acid residues in the side chain ranging from 12 to 24. Notably, the glutamic acid residues were not solely γ-linked, as is the case for all known methanofurans, but were identified by NMR as a mixture of α- and γ-linked amino acids. Considering the unusual peptide chain, the elucidation of the structure presented here sets the basis for further research on this cofactor, which is probably the largest cofactor known so far. PMID:26895963

  13. The One-carbon Carrier Methylofuran from Methylobacterium extorquens AM1 Contains a Large Number of α- and γ-Linked Glutamic Acid Residues.

    Science.gov (United States)

    Hemmann, Jethro L; Saurel, Olivier; Ochsner, Andrea M; Stodden, Barbara K; Kiefer, Patrick; Milon, Alain; Vorholt, Julia A

    2016-04-22

    Methylobacterium extorquens AM1 uses dedicated cofactors for one-carbon unit conversion. Based on the sequence identities of enzymes and activity determinations, a methanofuran analog was proposed to be involved in formaldehyde oxidation in Alphaproteobacteria. Here, we report the structure of the cofactor, which we termed methylofuran. Using an in vitro enzyme assay and LC-MS, methylofuran was identified in cell extracts and further purified. From the exact mass and MS-MS fragmentation pattern, the structure of the cofactor was determined to consist of a polyglutamic acid side chain linked to a core structure similar to the one present in archaeal methanofuran variants. NMR analyses showed that the core structure contains a furan ring. However, instead of the tyramine moiety that is present in methanofuran cofactors, a tyrosine residue is present in methylofuran, which was further confirmed by MS through the incorporation of a (13)C-labeled precursor. Methylofuran was present as a mixture of different species with varying numbers of glutamic acid residues in the side chain ranging from 12 to 24. Notably, the glutamic acid residues were not solely γ-linked, as is the case for all known methanofurans, but were identified by NMR as a mixture of α- and γ-linked amino acids. Considering the unusual peptide chain, the elucidation of the structure presented here sets the basis for further research on this cofactor, which is probably the largest cofactor known so far. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  14. Suspect screening of large numbers of emerging contaminants in environmental waters using artificial neural networks for chromatographic retention time prediction and high resolution mass spectrometry data analysis.

    Science.gov (United States)

    Bade, Richard; Bijlsma, Lubertus; Miller, Thomas H; Barron, Leon P; Sancho, Juan Vicente; Hernández, Felix

    2015-12-15

    The recent development of broad-scope high resolution mass spectrometry (HRMS) screening methods has resulted in a much improved capability for new compound identification in environmental samples. However, positive identifications at the ng/L concentration level rely on analytical reference standards for chromatographic retention time (tR) and mass spectral comparisons. Chromatographic tR prediction can play a role in increasing confidence in suspect screening efforts for new compounds in the environment, especially when standards are not available, but reliable methods are lacking. The current work focuses on the development of artificial neural networks (ANNs) for tR prediction in gradient reversed-phase liquid chromatography and applied along with HRMS data to suspect screening of wastewater and environmental surface water samples. Based on a compound tR dataset of >500 compounds, an optimized 4-layer back-propagation multi-layer perceptron model enabled predictions for 85% of all compounds to within 2min of their measured tR for training (n=344) and verification (n=100) datasets. To evaluate the ANN ability for generalization to new data, the model was further tested using 100 randomly selected compounds and revealed 95% prediction accuracy within the 2-minute elution interval. Given the increasing concern on the presence of drug metabolites and other transformation products (TPs) in the aquatic environment, the model was applied along with HRMS data for preliminary identification of pharmaceutically-related compounds in real samples. Examples of compounds where reference standards were subsequently acquired and later confirmed are also presented. To our knowledge, this work presents for the first time, the successful application of an accurate retention time predictor and HRMS data-mining using the largest number of compounds to preliminarily identify new or emerging contaminants in wastewater and surface waters. Copyright © 2015 Elsevier B.V. All rights

  15. Extensive unusual lesions on a large number of immersed human victims found to be from cookiecutter sharks (Isistius spp.): an examination of the Yemenia plane crash.

    Science.gov (United States)

    Ribéreau-Gayon, Agathe; Rando, Carolyn; Schuliar, Yves; Chapenoire, Stéphane; Crema, Enrico R; Claes, Julien; Seret, Bernard; Maleret, Vincent; Morgan, Ruth M

    2017-03-01

    Accurate determination of the origin and timing of trauma is key in medicolegal investigations when the cause and manner of death are unknown. However, distinction between criminal and accidental perimortem trauma and postmortem modifications can be challenging when facing unidentified trauma. Postmortem examination of the immersed victims of the Yemenia airplane crash (Comoros, 2009) demonstrated the challenges in diagnosing extensive unusual circular lesions found on the corpses. The objective of this study was to identify the origin and timing of occurrence (peri- or postmortem) of the lesions.A retrospective multidisciplinary study using autopsy reports (n = 113) and postmortem digital photos (n = 3 579) was conducted. Of the 113 victims recovered from the crash, 62 (54.9 %) presented unusual lesions (n = 560) with a median number of 7 (IQR 3 ∼ 13) and a maximum of 27 per corpse. The majority of lesions were elliptic (58 %) and had an area smaller than 10 cm 2 (82.1 %). Some lesions (6.8 %) also showed clear tooth notches on their edges. These findings identified most of the lesions as consistent with postmortem bite marks from cookiecutter sharks (Isistius spp.). It suggests that cookiecutter sharks were important agents in the degradation of the corpses and thus introduced potential cognitive bias in the research of the cause and manner of death. A novel set of evidence-based identification criteria for cookiecutter bite marks on human bodies is developed to facilitate more accurate medicolegal diagnosis of cookiecutter bites.

  16. Statistical Diversions

    Science.gov (United States)

    Petocz, Peter; Sowey, Eric

    2012-01-01

    The term "data snooping" refers to the practice of choosing which statistical analyses to apply to a set of data after having first looked at those data. Data snooping contradicts a fundamental precept of applied statistics, that the scheme of analysis is to be planned in advance. In this column, the authors shall elucidate the…

  17. Statistical Diversions

    Science.gov (United States)

    Petocz, Peter; Sowey, Eric

    2008-01-01

    In this article, the authors focus on hypothesis testing--that peculiarly statistical way of deciding things. Statistical methods for testing hypotheses were developed in the 1920s and 1930s by some of the most famous statisticians, in particular Ronald Fisher, Jerzy Neyman and Egon Pearson, who laid the foundations of almost all modern methods of…

  18. Scan Statistics

    CERN Document Server

    Glaz, Joseph

    2009-01-01

    Suitable for graduate students and researchers in applied probability and statistics, as well as for scientists in biology, computer science, pharmaceutical science and medicine, this title brings together a collection of chapters illustrating the depth and diversity of theory, methods and applications in the area of scan statistics.

  19. Practical Statistics

    CERN Document Server

    Lyons, L.

    2016-01-01

    Accelerators and detectors are expensive, both in terms of money and human effort. It is thus important to invest effort in performing a good statistical anal- ysis of the data, in order to extract the best information from it. This series of five lectures deals with practical aspects of statistical issues that arise in typical High Energy Physics analyses.

  20. Descriptive statistics.

    Science.gov (United States)

    Nick, Todd G

    2007-01-01

    Statistics is defined by the Medical Subject Headings (MeSH) thesaurus as the science and art of collecting, summarizing, and analyzing data that are subject to random variation. The two broad categories of summarizing and analyzing data are referred to as descriptive and inferential statistics. This chapter considers the science and art of summarizing data where descriptive statistics and graphics are used to display data. In this chapter, we discuss the fundamentals of descriptive statistics, including describing qualitative and quantitative variables. For describing quantitative variables, measures of location and spread, for example the standard deviation, are presented along with graphical presentations. We also discuss distributions of statistics, for example the variance, as well as the use of transformations. The concepts in this chapter are useful for uncovering patterns within the data and for effectively presenting the results of a project.