WorldWideScience

Sample records for large 2400mwth generation

  1. Large superconducting wind turbine generators

    DEFF Research Database (Denmark)

    Abrahamsen, Asger Bech; Magnusson, Niklas; Jensen, Bogi Bech

    2012-01-01

    and the rotation speed is lowered in order to limit the tip speed of the blades. The ability of superconducting materials to carry high current densities with very small losses might facilitate a new class of generators operating with an air gap flux density considerably higher than conventional generators...... and thereby having a smaller size and weight [1, 2]. A 5 MW superconducting wind turbine generator forms the basics for the feasibility considerations, particularly for the YBCO and MgB2 superconductors entering the commercial market. Initial results indicate that a 5 MW generator with an active weight of 34...

  2. Generation Expansion Planning Considering Integrating Large-scale Wind Generation

    DEFF Research Database (Denmark)

    Zhang, Chunyu; Ding, Yi; Østergaard, Jacob

    2013-01-01

    Generation expansion planning (GEP) is the problem of finding the optimal strategy to plan the Construction of new generation while satisfying technical and economical constraints. In the deregulated and competitive environment, large-scale integration of wind generation (WG) in power system has...... necessitated the inclusion of more innovative and sophisticated approaches in power system investment planning. A bi-level generation expansion planning approach considering large-scale wind generation was proposed in this paper. The first phase is investment decision, while the second phase is production...

  3. A large electrically excited synchronous generator

    DEFF Research Database (Denmark)

    2014-01-01

    adjacent neighbouring poles. In this way, a large electrically excited synchronous generator (EESG) is provided that readily enables a relatively large number of poles, compared to a traditional EESG, since the excitation coil in this design provides MMF for all the poles, whereas in a traditional EESG...

  4. GPU Generation of Large Varied Animated Crowds

    OpenAIRE

    Isaac Rudomin; Benjamín Hernández; Oriam de Gyves; Leonel Toledo; Ivan Rivalcoba; Sergio Ruiz

    2013-01-01

    ..We discuss several steps in the process of simulating and visualizing large and varied crowds in real time for consumer-level computers and graphic cards (GPUs). Animating varied crowds using a diversity of models and animations (assets) is complex and costly. One has to use models that are expensive if bought, take a long time to model, and consume too much memory and computing resources. We discuss methods for simulating, generating, animating and rendering crowds of varied aspect and a d...

  5. Generating Random Graphs with Large Girth

    CERN Document Server

    Bayati, Mohsen; Saberi, Amin

    2008-01-01

    We present a simple and efficient algorithm for randomly generating simple graphs without small cycles. These graphs can be used to design high performance Low-Density Parity -Check (LDPC) codes. For any constant k, alpha<1/2k(k+3) and m=O(n^{1+alpha}), our algorithm generate s an asymptotically uniform random graph with n vertices, m edges, and girth larger tha n k in polynomial time. To the best of our knowledge this is the first polynomial-algorith m for the problem. Our algorithm generates a graph by sequentially adding m edges to an empty graph with n vertices. Recently, these types of sequential methods for counting and random generation have been very successful.

  6. Outage maintenance checks on large generator windings

    Energy Technology Data Exchange (ETDEWEB)

    Nindra, B.; Jeney, S.I.; Slobodinsky, Y. [National Electric Coil, Columbus, OH (United States)

    1995-12-31

    In the present days of austerity, more constraints and pressures are being brought on the maintenance engineers to certify the generators for their reliability and life extension. The outages are shorter and intervals between the outages are becoming longer. The annual outages were very common when utilities had no regulatory constraints and also had standby capacities. Furthermore, due to lean and mean budgets, outage maintenance programs are being pursued more aggressively, so that longer interval outages can be achieved to ensure peak generator performance. This paper will discuss various visual checks, electrical tests and recommended fixes to achieve the above mentioned objectives, in case any deficiencies are found.

  7. Dynamic Test Generation for Large Binary Programs

    Science.gov (United States)

    2009-11-12

    Patrice Godefroid, Dennis Jeffries, and Adam Kiezun. The SAGE system builds on the iDNA/Time Travel Debugging and Nirvana infrastructure produced by... Nirvana [7] or Valgrind [74] (Catchconv is an example of the latter approach [70].) SAGE adopts offline trace-based constraint generation for two reasons

  8. Smooth Tracking Trajectory Generation of Large Antenna

    Directory of Open Access Journals (Sweden)

    Upnere S.

    2016-02-01

    Full Text Available The current paper presents an engineering approach for studies of the control algorithm designed for a mechanically robust large antenna. Feed-forward control methods with the 3rd-order polynomial tracking algorithm are supplemented to the original feed-back PID control system. Dynamical model of the existing servo system of 32m radio telescope has been developed to widen a case analysis of observation sessions and efficiency of the control algorithms due to limited access to an antenna. Algorithms along with the results from the system implemented on a real antenna as well as model results are presented.

  9. Aging assessment of large generator insulation based on PD measurements

    Institute of Scientific and Technical Information of China (English)

    YUE Bo; CHEN Xiaolin; CHENG Yonghong; XIE Hengkun

    2005-01-01

    The statistical parameters of phase resolved partial discharge (PD) distribution and ultra-wideband (UWB) characteristics of PD pulse are proposed for aging assessment of large generator insulation. Multi-stress aging tests of the model generator stator bar specimens were performed and PD measurements were conducted using both digital PD detector with frequency ranging from 40 kHz to 400 kHz and UWB PD detector with bandwidth from 10 MHz to 3 GHz at different aging stages. The test results show that the skewness and UWB frequency characteristics of PD can be taken as the characterization parameters for aging assessment of generator insulation. Furthermore, the measurement results of real generator stator bars show that these methods based on statistical parameters and UWB characteristics of PD are prospective for aging assessment and residual lifetime estimation of large generator stator insulation.

  10. Generation of large-scale winds in horizontally anisotropic convection

    CERN Document Server

    von Hardenberg, J; Provenzale, A; Spiegel, E A

    2015-01-01

    We simulate three-dimensional, horizontally periodic Rayleigh-B\\'enard convection between free-slip horizontal plates, rotating about a horizontal axis. When both the temperature difference between the plates and the rotation rate are sufficiently large, a strong horizontal wind is generated that is perpendicular to both the rotation vector and the gravity vector. The wind is turbulent, large-scale, and vertically sheared. Horizontal anisotropy, engendered here by rotation, appears necessary for such wind generation. Most of the kinetic energy of the flow resides in the wind, and the vertical turbulent heat flux is much lower on average than when there is no wind.

  11. Evolution and Next Generation of Large Cosmic-Ray Experiments

    Science.gov (United States)

    Olinto, Angela

    2016-03-01

    With collaborations involving as many as 32 countries, next generation astro-particle observatories are being built to understand the puzzling origin of the most energetic processes in the Universe. We will review some recent results and the effort behind next generation observatories, which include large arrays of detectors and space missions to study high to ultra-high energy cosmic-rays, neutrinos, and gamma-rays. The great opportunity of word-wide scientific productivity and funding motivates these large-scale efforts, which also face many challenges due to geopolitical events and differences in science funding cultures.

  12. Large scale renewable power generation advances in technologies for generation, transmission and storage

    CERN Document Server

    Hossain, Jahangir

    2014-01-01

    This book focuses on the issues of integrating large-scale renewable power generation into existing grids. The issues covered in this book include different types of renewable power generation along with their transmission and distribution, storage and protection. It also contains the development of medium voltage converters for step-up-transformer-less direct grid integration of renewable generation units, grid codes and resiliency analysis for large-scale renewable power generation, active power and frequency control and HVDC transmission. The emerging SMES technology for controlling and int

  13. Variability in large-scale wind power generation: Variability in large-scale wind power generation

    Energy Technology Data Exchange (ETDEWEB)

    Kiviluoma, Juha [VTT Technical Research Centre of Finland, Espoo Finland; Holttinen, Hannele [VTT Technical Research Centre of Finland, Espoo Finland; Weir, David [Energy Department, Norwegian Water Resources and Energy Directorate, Oslo Norway; Scharff, Richard [KTH Royal Institute of Technology, Electric Power Systems, Stockholm Sweden; Söder, Lennart [Royal Institute of Technology, Electric Power Systems, Stockholm Sweden; Menemenlis, Nickie [Institut de recherche Hydro-Québec, Montreal Canada; Cutululis, Nicolaos A. [DTU, Wind Energy, Roskilde Denmark; Danti Lopez, Irene [Electricity Research Centre, University College Dublin, Dublin Ireland; Lannoye, Eamonn [Electric Power Research Institute, Palo Alto California USA; Estanqueiro, Ana [LNEG, Laboratorio Nacional de Energia e Geologia, UESEO, Lisbon Spain; Gomez-Lazaro, Emilio [Renewable Energy Research Institute and DIEEAC/EDII-AB, Castilla-La Mancha University, Albacete Spain; Zhang, Qin [State Grid Corporation of China, Beijing China; Bai, Jianhua [State Grid Energy Research Institute Beijing, Beijing China; Wan, Yih-Huei [National Renewable Energy Laboratory, Transmission and Grid Integration Group, Golden Colorado USA; Milligan, Michael [National Renewable Energy Laboratory, Transmission and Grid Integration Group, Golden Colorado USA

    2015-10-25

    The paper demonstrates the characteristics of wind power variability and net load variability in multiple power systems based on real data from multiple years. Demonstrated characteristics include probability distribution for different ramp durations, seasonal and diurnal variability and low net load events. The comparison shows regions with low variability (Sweden, Spain and Germany), medium variability (Portugal, Ireland, Finland and Denmark) and regions with higher variability (Quebec, Bonneville Power Administration and Electric Reliability Council of Texas in North America; Gansu, Jilin and Liaoning in China; and Norway and offshore wind power in Denmark). For regions with low variability, the maximum 1 h wind ramps are below 10% of nominal capacity, and for regions with high variability, they may be close to 30%. Wind power variability is mainly explained by the extent of geographical spread, but also higher capacity factor causes higher variability. It was also shown how wind power ramps are autocorrelated and dependent on the operating output level. When wind power was concentrated in smaller area, there were outliers with high changes in wind output, which were not present in large areas with well-dispersed wind power.

  14. Generation of nonclassical states in a large detuning cavity

    Institute of Scientific and Technical Information of China (English)

    Zhang Ying-Jie; Ren Ting-Qi; Xia Yun-Jie

    2008-01-01

    By using the theory of cavity QED, we study the system in which a two-level atom interacts with a cavity in the case of large detuning. Through the selective detecting of atomic state, SchrSdinger cat states and entangled coherent states are easily generated. When the atom is driven by a weak classical field and the cavity field is in the Schr(o)dinger cat state, we study the conditions of generating the Fock states and the maximal success probability. The maximal success probability in our scheme is larger than the previous one.

  15. Large-scale flow generation by inhomogeneous helicity

    CERN Document Server

    Yokoi, Nobumitsu

    2015-01-01

    The effect of kinetic helicity (velocity--vorticity correlation) on turbulent momentum transport is investigated. The turbulent kinetic helicity (pseudoscalar) enters into the Reynolds stress (mirrorsymmetric tensor) expression in the form of a helicity gradient as the coupling coefficient for the mean vorticity and/or the angular velocity (axial vector), which suggests the possibility of mean-flow generation in the presence of inhomogeneous helicity. This inhomogeneous helicity effect, which was previously confirmed at the level of a turbulence- or closure-model simulation, is examined with the aid of direct numerical simulations of rotating turbulence with non-uniform helicity sustained by an external forcing. The numerical simulations show that the spatial distribution of the Reynolds stress is in agreement with the helicity-related term coupled with the angular velocity, and that a large-scale flow is generated in the direction of angular velocity. Such a large-scale flow is not induced in the case of hom...

  16. Next-generation sequencing and large genome assemblies

    OpenAIRE

    Henson, Joseph; Tischler, German; Ning, Zemin

    2012-01-01

    The next-generation sequencing (NGS) revolution has drastically reduced time and cost requirements for sequencing of large genomes, and also qualitatively changed the problem of assembly. This article reviews the state of the art in de novo genome assembly, paying particular attention to mammalian-sized genomes. The strengths and weaknesses of the main sequencing platforms are highlighted, leading to a discussion of assembly and the new challenges associated with NGS data. Current approaches ...

  17. Large photovoltages generated by plant photosystem I crystals

    Energy Technology Data Exchange (ETDEWEB)

    Toporik, Hila; Carmeli, Chanoch; Nelson, Nathan [Department of Biochemistry and Molecular Biology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel); Carmeli, Itai [School of Chemistry, Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 (Israel); Volotsenko, Irina; Molotskii, Michel; Rosenwaks, Yossi [Department of Physical Electronics, Faculty of Engineering, Tel Aviv University, Tel Aviv 69978 (Israel)

    2012-06-12

    Micrometer-thick plant photosystem I crystals made of up to 1000 layers of serially arranged protein complexes generate unprecedented high photovoltages when placed on a conducting solid surface and measured using Kelvin probe force microscopy. The successive layers form serially photoinduced dipoles in the crystal that give rise to electric fields as large as 100 kV cm{sup -1}. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. Development of large wind energy power generation system

    Science.gov (United States)

    1985-01-01

    The background and development of an experimental 100 kW wind-energy generation system are described, and the results of current field tests are presented. The experimental wind turbine is a two-bladed down-wind horizontal axis propeller type with a 29.4 m diameter rotor and a tower 28 m in height. The plant was completed in March, 1983, and has been undergoing trouble-free tests since then. The present program calls for field tests during two years from fiscal 1983 to 1984. The development of technologies relating to the linkage and operation of wind-energy power generation system networks is planned along with the acquisition of basic data for the development of a large-scale wind energy power generation system.

  19. Small shape deviations causes complex dynamics in large electric generators

    Science.gov (United States)

    Lundström, Niklas L. P.; Grafström, Anton; Aidanpää, Jan-Olov

    2014-05-01

    We prove that combinations of small eccentricity, ovality and/or triangularity in the rotor and stator can produce complex whirling motions of an unbalanced rotor in large synchronous generators. It is concluded which structures of shape deviations that are more harmful, in the sense of producing complex whirling motions, than others. For each such structure, we derive simplified equations of motions from which we conclude analytically the relation between shape deviations and mass unbalance that yield non-smooth whirling motions. Finally we discuss validity of our results in the sense of modeling of the unbalanced magnetic pull force.

  20. Five Large Generation Groups:Competing in Capital Operation

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Since the reform of electric power industry in 2002,the newly established five large generation groups have been persisting in the development strategy of "taking electricity as the core and extending to up-and-downstream businesses." Stringent measures were taken in capital operation and their potential has been shown through electric power assets acquiring,coal and financial resources investing,capital market financing as well as power utility restructuring.The five groups are playing more and more important roles in merger and acquisition (M&A) and capital markets.

  1. Ultra-large scale cosmology with next-generation experiments

    CERN Document Server

    Alonso, David; Ferreira, Pedro G; Maartens, Roy; Santos, Mario G

    2015-01-01

    Future surveys of large-scale structure will be able to measure perturbations on the scale of the cosmological horizon, and so could potentially probe a number of novel relativistic effects that are negligibly small on sub-horizon scales. These effects leave distinctive signatures in the power spectra of clustering observables and, if measurable, would open a new window on relativistic cosmology. We quantify the size and detectability of the effects for a range of future large-scale structure surveys: spectroscopic and photometric galaxy redshift surveys, intensity mapping surveys of neutral hydrogen, and continuum surveys of radio galaxies. Our forecasts show that next-generation experiments, reaching out to redshifts z ~ 4, will not be able to detect previously-undetected general-relativistic effects from the single-tracer power spectra alone, although they may be able to measure the lensing magnification in the auto-correlation. We also perform a rigorous joint forecast for the detection of primordial non-...

  2. Next Generation Large Capacity Long Distance Fiber To The Home

    Directory of Open Access Journals (Sweden)

    N. M. A. Ayad and M. Elazazy

    2011-07-01

    Full Text Available Optical device technologies for photonic networks, are focusing on integrated optical device technologies for digital coherent optical transmission technologies. With the rapid spread of fiber to the home (FTTH, broadband video services and mobile Internet devices now require a highly functional optical network infrastructure with a large capacity 100-Gbit/s/channel system based on digital coherent technology is considered to be a promising candidate for next-generation large-capacity long-distance optical communication systems. The optical components required for such systems, such as Polarization Division Multiplexed Quadrate Phase Shift Keying (PDM-QPSK optical modulator, integrated receiver, and local light source, are under development. Opto-electrical integration technologies, which enable us to construct small, low-cost, and highly functional optical components, will play an important role in providing cost-effective transmission equipment for future 100-Gbit/s/ch and post-100-Gbit/s/ch optical communications

  3. Large-scale generation of cell-derived nanovesicles

    Science.gov (United States)

    Jo, W.; Kim, J.; Yoon, J.; Jeong, D.; Cho, S.; Jeong, H.; Yoon, Y. J.; Kim, S. C.; Gho, Y. S.; Park, J.

    2014-09-01

    Exosomes are enclosed compartments that are released from cells and that can transport biological contents for the purpose of intercellular communications. Research into exosomes is hindered by their rarity. In this article, we introduce a device that uses centrifugal force and a filter with micro-sized pores to generate a large quantity of cell-derived nanovesicles. The device has a simple polycarbonate structure to hold the filter, and operates in a common centrifuge. Nanovesicles are similar in size and membrane structure to exosomes. Nanovesicles contain intracellular RNAs ranging from microRNA to mRNA, intracellular proteins, and plasma membrane proteins. The quantity of nanovesicles produced using the device is 250 times the quantity of naturally secreted exosomes. Also, the quantity of intracellular contents in nanovesicles is twice that in exosomes. Nanovesicles generated from murine embryonic stem cells can transfer RNAs to target cells. Therefore, this novel device and the nanovesicles that it generates are expected to be used in exosome-related research, and can be applied in various applications such as drug delivery and cell-based therapy.

  4. Pseudo—Random Test Generation for Large Combinational Circuits

    Institute of Scientific and Technical Information of China (English)

    李忠诚; 闵应骅

    1992-01-01

    In this paper, a simulation system of pseudo-random testing is described first to investigate the characteristics of pseudo-random testing.Several interesting experimntal results are obtained.It is found out that initial states of pseudo-random sequences have little effect on fault coverage.Fixed connection between lfsr outputs and circuit inputs in which the number of LFSR stages m is less than the number of circuit inputs n leads to low fault coverage,and the fault coverage is reduced as m decreases.The local unrandomness of pseudo-random sequences is exposed clearly.Geneally,when an LFSR is employed as a pseudo-random generator,there are at least as many LFSR stages as circuit inputs.However,for large circuits under test with hundreds of inputs,there are drawbacks of using and LFSR with hundreds of stages.In the paper,a new design for a pseudo-random pattern generator is proposed in whic mgenerator.

  5. Noise generated by flow through large butterfly valves

    Science.gov (United States)

    Huff, Ronald G.

    1987-01-01

    A large butterfly valve (1.37 m diam) was acoustically tested to measure the noise generated and propagating in both the upstream and downstream directions. The experimental investigation used wall mounted pressure transducers to measure the fluctuating component of the pipe static pressure upstream and downstream of the valve. Microphones upstream of the pipe inlet and located in a plenum were used to measure the noise radiated from the valve in the upstream direction. Comparison of the wall pressure downstream of the valve to a prediction were made. Reasonable agreement was obtained with the valve operating at a choked condition. The noise upstream of the valve is 30 dB less than that measured downstream.

  6. Next-generation sequencing and large genome assemblies.

    Science.gov (United States)

    Henson, Joseph; Tischler, German; Ning, Zemin

    2012-06-01

    The next-generation sequencing (NGS) revolution has drastically reduced time and cost requirements for sequencing of large genomes, and also qualitatively changed the problem of assembly. This article reviews the state of the art in de novo genome assembly, paying particular attention to mammalian-sized genomes. The strengths and weaknesses of the main sequencing platforms are highlighted, leading to a discussion of assembly and the new challenges associated with NGS data. Current approaches to assembly are outlined and the various software packages available are introduced and compared. The question of whether quality assemblies can be produced using short-read NGS data alone, or whether it must be combined with more expensive sequencing techniques, is considered. Prospects for future assemblers and tests of assembly performance are also discussed.

  7. Study on safety operation for large hydroelectric generator unit

    Science.gov (United States)

    Yan, Z. G.; Cui, T.; Zhou, L. J.; Zhi, F. L.; Wang, Z. W.

    2012-11-01

    Hydroelectric generator unit is a complex mechanical system which is composed of hydraulic turbine and electric generator. Rotary system is supported by the bearing bracket and the reinforced concrete structures, and vibration problem can't be avoided in the process of operating. Many large-scale hydroelectric units have been damaged because of the vibration problem in recent years. As the increase of the hydraulic turbine unit capacity and water head, the safe operation of hydraulic turbine has become a focus research in many countries. The operating characteristics of the hydraulic turbine have obvious differences at different working conditions. Based on the combination of field measurement and theoretical calculation, this paper shows a deep research on the safe operation of a large-scale Francis turbine unit. Firstly, the measurements of vibration, swing, pressure fluctuation and noise were carried out at 4 different heads. And also the relationships between vibrations and pressure fluctuations at different heads and working conditions were analysed deeply. Then the scientific prediction of safe operation for the unit at high head were done based on the CFD numerical calculation. Finally, this paper shows the division of the operating zone for the hydroelectric unit. According to the experimental results (vibrations, swings, pressure fluctuations and noise) as well as the theoretical results, the operating zone of the unit has been divided into three sections: prohibited operating zone, transition operating zone and safe operating zone. After this research was applied in the hydropower station, the security and economic efficiency of unit increased greatly, and enormous economic benefits and social benefits have been obtained.

  8. Tidal generation of large sub-mesoscale eddy dipoles

    Directory of Open Access Journals (Sweden)

    W. Callendar

    2011-08-01

    Full Text Available Numerical simulations of tidal flow past Cape St. James on the south tip of Haida Gwaii (Queen Charlotte Islands are presented that indicate mesoscale dipoles are formed from coalescing tidal eddies. Observations in this region demonstrate robust eddy generation at the Cape, with the primary process being flow separation of buoyant or wind driven outflows forming large anti-cyclonic, negative potential vorticity, Haida Eddies. However, there are other times where dipoles are observed in satellites, indicating a source of positive potential vorticity must also be present. The simulations here build on previous work that implicates oscillating tidal flow past the cape in creating the positive vorticity. Small headland eddies of alternating vorticity are created each tide. During certain tidal cycles, the headland eddies coalesce and self organize in such a way as to create large >20-km diameter eddies that then self-advect into deep water. The self advection speed is faster than the beta drift of anti-cyclones, and the propagation direction appears to be more southerly than typical Haida Eddies, though the model contains no mean wind-driven flows. These eddies are smaller than Haida Eddies, but given their tidal origin, may represent a more consistent source of coastal water that is injected into the interior of the subpolar gyre.

  9. Tidal generation of large sub-mesoscale eddy dipoles

    Science.gov (United States)

    Callendar, W.; Klymak, J. M.; Foreman, M. G. G.

    2011-08-01

    Numerical simulations of tidal flow past Cape St. James on the south tip of Haida Gwaii (Queen Charlotte Islands) are presented that indicate mesoscale dipoles are formed from coalescing tidal eddies. Observations in this region demonstrate robust eddy generation at the Cape, with the primary process being flow separation of buoyant or wind driven outflows forming large anti-cyclonic, negative potential vorticity, Haida Eddies. However, there are other times where dipoles are observed in satellites, indicating a source of positive potential vorticity must also be present. The simulations here build on previous work that implicates oscillating tidal flow past the cape in creating the positive vorticity. Small headland eddies of alternating vorticity are created each tide. During certain tidal cycles, the headland eddies coalesce and self organize in such a way as to create large >20-km diameter eddies that then self-advect into deep water. The self advection speed is faster than the beta drift of anti-cyclones, and the propagation direction appears to be more southerly than typical Haida Eddies, though the model contains no mean wind-driven flows. These eddies are smaller than Haida Eddies, but given their tidal origin, may represent a more consistent source of coastal water that is injected into the interior of the subpolar gyre.

  10. Tidal generation of large sub-mesoscale eddy dipoles

    Directory of Open Access Journals (Sweden)

    W. Callendar

    2011-04-01

    Full Text Available Numerical simulations of tidal flow past Cape St. James on the south tip of Haida Gwai (Queen Charlotte Islands are presented that indicate mesoscale dipoles are formed from coalescing tidal eddies. Observations in this region demonstrate robust eddy generation at the Cape, with the primary process being flow separation of buoyant or wind driven outflows forming large anti-cyclonic, negative potential vorticity, Haida Eddies. However, there are other times where dipoles are observed in satellites, indicating a source of positive potential vorticity must also be present. The simulations here build on previous work that implicates oscillating tidal flow past the cape in creating the positive vorticity. Small headland eddies of alternating vorticity are created each tide. During certain tidal cycles, the headland eddies coalesce and self organize in such a way as to create large >20-km diameter eddies that then self-advect into deep water. The self advection speed is faster than the beta drift of anti-cyclones, and the propagation direction appears to be more southerly than typical Haida Eddies, though the model contains no mean wind-driven flows. These eddies are smaller than Haida Eddies, but given their tidal origin, may represent a more consistent source of coastal water that is injected into to the interior of the subpolar gyre.

  11. Fuzzy generation scheduling for a generation company (GenCo) with large scale wind farms

    Energy Technology Data Exchange (ETDEWEB)

    Siahkali, H., E-mail: Siahkali@ee.sharif.ed [Department of Electrical Engineering, Sharif University of Technology, Azadi Ave., P.O. Box 11365-8639, Tehran (Iran, Islamic Republic of); Vakilian, M. [Department of Electrical Engineering, Sharif University of Technology, Azadi Ave., P.O. Box 11365-8639, Tehran (Iran, Islamic Republic of)

    2010-10-15

    Wind power is a promising alternative in power generation because of its tremendous environmental and social benefits. Generation scheduling (GS) is more important in a power system integrating wind farms. Unlike conventional power generation sources, wind power generators supply intermittent power because of uncertainty in resource. This paper presents a fuzzy approach to the generation scheduling problem of a GenCo considering uncertainties in parameters or constraints such as load, reserve and available wind power generation. The modeling of constraints is an important issue in power system scheduling. A fuzzy optimization approach is an approach that can be used to obtain the generation scheduling under an uncertain environment. In this paper, a fuzzy optimization-based method is developed to solve power system GS problem with fuzzy objective and constraints. The crisp formulation of this GS problem is firstly defined and is rearranged by introduction of a membership function of some constraints and objective function. Then, this fuzzy optimization problem is converted to a crisp optimization and solved using GAMS software by mixed integer nonlinear programming. Employing the fuzzy optimization GS, it is expected that in practice a higher profit would be achieved in the operation and cost management of a real power system with large scale wind farms in different level of constraints' satisfaction. The proposed approach is applied to a sample system (including six conventional units and two wind farms) and the results are compared with the results of crisp solution. This approach is also applied to a larger test case to demonstrate the robustness of this fuzzy optimization method.

  12. Large eddy simulation of the flow through a swirl generator

    Energy Technology Data Exchange (ETDEWEB)

    Conway, Stephen

    1998-12-01

    The advances made in computer technology over recent years have led to a great increase in the engineering problems that can be studied using CFD. The computation of flows over and through complex geometries at relatively high Reynolds numbers is becoming more common using the Large Eddy Simulation (LES) technique. Direct numerical simulations of such flows is still beyond the capacity of todays fastest supercomputers, requiring excessive computational times and memory. In addition, traditional Reynolds Averaged Navier Stokes (RANS) methods are known to have limited applicability in a wide range of engineering flow situations. In this thesis LES has been used to simulate the flow through a cascade of guidance vanes, more commonly known as a swirl generator, positioned at the inlet to a gas turbine combustion chamber. This flow case is of interest because of the complex flow phenomena which occur within the swirl generator, which include compressibility effects, different types of flow instabilities, transition, laminar and turbulent separation and near wall turbulence. It is also of interest because it fits very well into the range of engineering applications that can be studied using LES. Two computational grids with different resolutions and two subgrid scale stress models were used in the study. The effects of separation and transition are investigated. A vortex shedding frequency from the guidance vanes is determined which is seen to be dependent on the angle of incident air flow. Interaction between the movement of the separation region and the shedding frequency is also noted. Such vortex shedding phenomena can directly affect the quality of fuel and air mixing within the combustion chamber and can in some cases induce vibrations in the gas turbine structure. Comparisons between the results obtained using different grid resolutions with an implicit and a dynamic divergence (DDM) subgrid scale stress models are also made 32 refs, 35 figs, 2 tabs

  13. Development of the control assembly pattern and dynamic analysis of the generation IV large gas-cooled fast reactor (GFR); Developpement du design d'un assemblage de controle et analyse dynamique des reacteurs a neutrons rapides de quatrieme generation refroidis au gaz

    Energy Technology Data Exchange (ETDEWEB)

    Girardin, G.

    2009-07-09

    Among the systems selected by the GIF, the Gas-cooled Fast Reactor (GFR) is a highly innovative system with advanced fuel geometry and materials. It is in the context of the large, 2400 MWth reference GFR design that the present doctoral research has been conducted, the principal aim having been to develop and qualify the control assembly (CA) pattern and corresponding CA implementation scheme for this system. The work has been carried out in three successive and complementary phases: (1) validation of the neutronics tools, (2) the CA pattern development and related static analysis, and (3) dynamic core behavior studies for hypothetical CA driven transients. During the first phase of the thesis, the reference PROTEUS test lattice from these experiments has been analyzed with ERANOS-2.0 and its associated, adjusted nuclear data library ERALIB1. Additionally, benchmark calculations were performed with the Monte Carlo code MCNPX, allowing one to both check the deterministic results and to analyze the sensitivity to different modern data libraries. It has been found that, for the main reaction rate ratios, the new analysis of the GCFR-PROTEUS reference lattice generally yields good agreement - within 1{sigma} measurement uncertainty - with experimental values and with the Monte Carlo simulations. As shown by the analysis, the predictions were in somewhat better agreement in the case of the adjusted ERALIB1 library. The applicability of ERANOS-2.0/ERALIB1 as the reference neutronics tool for the GFR analysis could thus be demonstrated. Furthermore, neutronics aspects related to the novel features of the GFR, for which new experimental investigations are needed, were highlighted. In the second phase of the research, the CA pattern was developed for the GFR, based on iterative neutronics and thermal-hydraulics calculations, 2D and 3D neutronics models for the reactor core having first been set up using the reference ERANOS-2.0/ERALIB1 computational scheme. For the thermal

  14. Next Generation Very Large Array: The Cradle of Life

    Science.gov (United States)

    Isella, Andrea; Hull, Charles L. H.; Moullet, Arielle; ngVLA Cradle of Life

    2017-01-01

    This paper discusses compelling science cases for a future long-baseline interferometer operating at millimeter and centimeter wavelengths, like the proposed Next Generation Vary Large Array (ngVLA). We report on the activities of the Cradle of Life science working group, which focused on the formation of low- and high-mass stars, the formation of planets and evolution of protoplanetary disks, the physical and compositional study of Solar System bodies, and the possible detection of radio signals from extraterrestrial civilizations. We propose 19 scientific projects based on the current specification of the ngVLA. Five of them are highlighted as possible Key Science Projects: (1) Resolving the density structure and dynamics of the youngest HII regions and high-mass protostellar jets, (2) Unveiling binary/multiple protostars at higher resolution, (3) Mapping planet formation regions in nearby disks on scales down to 1 AU, (4) Studying the formation of complex molecules, and (5) Deep atmospheric mapping of giant planets in the Solar System. For each of these projects, we discuss the scientific importance and feasibility. The results presented here should be considered as the beginning of a more in-depth analysis of the science enabled by such a facility, and are by no means complete or exhaustive.

  15. Intense THz Pulses with large ponderomotive potential generated from large aperture photoconductive antennas.

    Science.gov (United States)

    Ropagnol, X; Khorasaninejad, M; Raeiszadeh, M; Safavi-Naeini, S; Bouvier, M; Côté, C Y; Laramée, A; Reid, M; Gauthier, M A; Ozaki, T

    2016-05-30

    We report the generation of free space terahertz (THz) pulses with energy up to 8.3 ± 0.2 µJ from an encapsulated interdigitated ZnSe Large Aperture Photo-Conductive Antenna (LAPCA). An aperture of 12.2 cm2 is illuminated using a 400 nm pump laser with multi-mJ energies at 10 Hz repetition rate. The calculated THz peak electric field is 331 ± 4 kV/cm with a spectrum characterized by a median frequency of 0.28 THz. Given its relatively low frequency, this THz field will accelerate charged particles efficiently having very large ponderomotive energy of 15 ± 1 eV for electrons in vacuum. The scaling of the emission is studied with respect to the dimensions of the antenna, and it is observed that the capacitance of the LAPCA leads to a severe decrease in and distortion of the biasing voltage pulse, fundamentally limiting the maximum applied bias field and consequently the maximum energy of the radiated THz pulses. In order to demonstrate the advantages of this source in the strong field regime, an open-aperture Z-scan experiment was performed on n-doped InGaAs, which showed significant absorption bleaching.

  16. Electric Generators and their Control for Large Wind Turbines

    DEFF Research Database (Denmark)

    2017-01-01

    The electric generator and its power electronics interface for wind turbines (WTs) have evolved rapidly toward higher reliability and reduced cost of energy in the last 40 years. This chapter describes the up-to-date electric generators existing in the wind power industry, namely, the doubly fed...

  17. Superconducting light generator for large offshore wind turbines

    Science.gov (United States)

    Sanz, S.; Arlaban, T.; Manzanas, R.; Tropeano, M.; Funke, R.; Kováč, P.; Yang, Y.; Neumann, H.; Mondesert, B.

    2014-05-01

    Offshore wind market demands higher power rate and reliable turbines in order to optimize capital and operational cost. These requests are difficult to overcome with conventional generator technologies due to a significant weight and cost increase with the scaling up. Thus superconducting materials appears as a prominent solution for wind generators, based on their capacity to held high current densities with very small losses, which permits to efficiently replace copper conductors mainly in the rotor field coils. However the state-of-the-art superconducting generator concepts still seem to be expensive and technically challenging for the marine environment. This paper describes a 10 MW class novel direct drive superconducting generator, based on MgB2 wires and a modular cryogen free cooling system, which has been specifically designed for the offshore wind industry needs.

  18. Large optical glass blanks for the ELT generation

    Science.gov (United States)

    Jedamzik, Ralf; Petzold, Uwe; Dietrich, Volker; Wittmer, Volker; Rexius, Olga

    2016-07-01

    The upcoming extremely large telescope projects like the E-ELT, TMT or GMT telescopes require not only large amount of mirror blank substrates but have also sophisticated instrument setups. Common instrument components are atmospheric dispersion correctors that compensate for the varying atmospheric path length depending on the telescope inclination angle. These elements consist usually of optical glass blanks that have to be large due to the increased size of the focal beam of the extremely large telescopes. SCHOTT has a long experience in producing and delivering large optical glass blanks for astronomical applications up to 1 m and in homogeneity grades up to H3 quality in the past. The most common optical glass available in large formats is SCHOTT N-BK7. But other glass types like F2 or LLF1 can also be produced in formats up to 1 m. The extremely large telescope projects partly demand atmospheric dispersion components even in sizes beyond 1m up to a range of 1.5 m diameter. The production of such large homogeneous optical glass banks requires tight control of all process steps. To cover this demand in the future SCHOTT initiated a research project to improve the large optical blank production process steps from melting to annealing and measurement. Large optical glass blanks are measured in several sub-apertures that cover the total clear aperture of the application. With SCHOTT's new stitching software it is now possible to combine individual sub-aperture measurements to a total homogeneity map of the blank. In this presentation first results will be demonstrated.

  19. Rotor dynamic considerations for large wind power generator systems

    Science.gov (United States)

    Ormiston, R. A.

    1973-01-01

    Successful large, reliable, low maintenance wind turbines must be designed with full consideration for minimizing dynamic response to aerodynamic, inertial, and gravitational forces. Much of existing helicopter rotor technology is applicable to this problem. Compared with helicopter rotors, large wind turbines are likely to be relatively less flexible with higher dimensionless natural frequencies. For very large wind turbines, low power output per unit weight and stresses due to gravitational forces are limiting factors. The need to reduce rotor complexity to a minimum favors the use of cantilevered (hingeless) rotor configurations where stresses are relieved by elastic deformations.

  20. Design Methodology of Large-scale Thermoelectric Generation

    DEFF Research Database (Denmark)

    Chen, Min; Gao, Junling; Zhu, Junpeng

    2011-01-01

    A thermoelectric generation system (TEGS) consists of not only thermoelectric modules (TEMs), but also the external load circuitry and the fluidic heat sources. In this paper, a system-level model is proposed in the SPICE-compatible environment to seamlessly integrate the complete fluid...

  1. Generating large misalignments in gapped and binary discs

    Science.gov (United States)

    Owen, James E.; Lai, Dong

    2017-08-01

    Many protostellar gapped and binary discs show misalignments between their inner and outer discs; in some cases, ˜70° misalignments have been observed. Here, we show that these misalignments can be generated through a secular resonance between the nodal precession of the inner disc and the precession of the gap-opening (stellar or massive planetary) companion. An evolving protostellar system may naturally cross this resonance during its lifetime due to disc dissipation and/or companion migration. If resonance crossing occurs on the right time-scale, of the order of a few million years, characteristic for young protostellar systems, the inner and outer discs can become highly misaligned, with misalignments ≳ 60° typical. When the primary star has a mass of order a solar mass, generating a significant misalignment typically requires the companion to have a mass of ˜0.01-0.1 M⊙ and an orbital separation of tens of astronomical units. The recently observed companion in the cavity of the gapped, highly misaligned system HD 142527 satisfies these requirements, indicating that a previous resonance crossing event misaligned the inner and outer discs. Our scenario for HD 142527's misaligned discs predicts that the companion's orbital plane is aligned with the outer disc's; this prediction should be testable with future observations as the companion's orbit is mapped out. Misalignments observed in several other gapped disc systems could be generated by the same secular resonance mechanism.

  2. Observation of a Turbulence-Generated Large Scale Magnetic Field

    CERN Document Server

    Spence, E J; Kendrick, R D; Nornberg, M D

    2006-01-01

    A uniform magnetic field is applied to a spherical, turbulent flow of liquid sodium. An induced magnetic dipole moment is measured which cannot be generated by the interaction of the axisymmetric mean flow with the applied field, indicating the presence of a turbulent electromotive force. It is shown that the induced dipole moment should vanish for any axisymmetric laminar flow. Also observed is the production of toroidal magnetic field from applied poloidal magnetic field (the omega-effect). Its potential role in the production of the induced dipole is discussed.

  3. A noise generation and propagation model for large wind farms

    DEFF Research Database (Denmark)

    Bertagnolio, Franck

    2016-01-01

    A wind turbine noise calculation model is combined with a ray tracing method in order to estimate wind farm noise in its surrounding assuming an arbitrary topography. The wind turbine noise model is used to generate noise spectra for which each turbine is approximated as a point source. However......, the detailed three-dimensional directivity features are taken into account for the further calculation of noise propagation over the surrounding terrain. An arbitrary number of turbines constituting a wind farm can be spatially distributed. The noise from each individual turbine is propagated into the far......-field using the ray tracing method. These results are added up assuming the noise from each turbine is uncorrelated. The methodology permits to estimate a wind farm noise map over the surrounding terrain in a reasonable amount of computational time on a personal computer....

  4. Implementation of a large solar collector for electric charge generation

    Science.gov (United States)

    Leake, Skye; McGuire, Thomas; Parsons, Michael; Hirsch, Michael P.; Straub, Jeremy

    2016-05-01

    This paper evaluates use of solar flux concentrator systems with photovoltaic cells, it provides analysis on overall economic feasibility based on cost/benefit considerations. Properties evaluated include launch volume/mass, efficiency once in a functioning configuration and service life. Production time will also be discussed considering research on existing technology to expedite integration. Solar energy is primarily harvested via solar panels. With the utilization of a large mirrored dish, solar energy can be concentrated to maximize the efficiency of photovoltaic systems form a cost/benefit standpoint. The design concepts for these systems include fully rigid, tensioned over frame, and inflatable approaches. The efficiency of such systems will be discussed. Pre-existing systems, such as the photovoltaic blanket arrays on the international space station, will be considered. Areas of consideration include cost/output ratio, the efficiency of the array, and the system's service life. Prior work on ridged, tensioned, and inflatable mirrored systems will be presented.

  5. Advances in Parallelization for Large Scale Oct-Tree Mesh Generation

    Science.gov (United States)

    O'Connell, Matthew; Karman, Steve L.

    2015-01-01

    Despite great advancements in the parallelization of numerical simulation codes over the last 20 years, it is still common to perform grid generation in serial. Generating large scale grids in serial often requires using special "grid generation" compute machines that can have more than ten times the memory of average machines. While some parallel mesh generation techniques have been proposed, generating very large meshes for LES or aeroacoustic simulations is still a challenging problem. An automated method for the parallel generation of very large scale off-body hierarchical meshes is presented here. This work enables large scale parallel generation of off-body meshes by using a novel combination of parallel grid generation techniques and a hybrid "top down" and "bottom up" oct-tree method. Meshes are generated using hardware commonly found in parallel compute clusters. The capability to generate very large meshes is demonstrated by the generation of off-body meshes surrounding complex aerospace geometries. Results are shown including a one billion cell mesh generated around a Predator Unmanned Aerial Vehicle geometry, which was generated on 64 processors in under 45 minutes.

  6. Thermal power generation projects ``Large Scale Solar Heating``; EU-Thermie-Projekte ``Large Scale Solar Heating``

    Energy Technology Data Exchange (ETDEWEB)

    Kuebler, R.; Fisch, M.N. [Steinbeis-Transferzentrum Energie-, Gebaeude- und Solartechnik, Stuttgart (Germany)

    1998-12-31

    The aim of this project is the preparation of the ``Large-Scale Solar Heating`` programme for an Europe-wide development of subject technology. The following demonstration programme was judged well by the experts but was not immediately (1996) accepted for financial subsidies. In November 1997 the EU-commission provided 1,5 million ECU which allowed the realisation of an updated project proposal. By mid 1997 a small project was approved, that had been requested under the lead of Chalmes Industriteteknik (CIT) in Sweden and is mainly carried out for the transfer of technology. (orig.) [Deutsch] Ziel dieses Vorhabens ist die Vorbereitung eines Schwerpunktprogramms `Large Scale Solar Heating`, mit dem die Technologie europaweit weiterentwickelt werden sollte. Das daraus entwickelte Demonstrationsprogramm wurde von den Gutachtern positiv bewertet, konnte jedoch nicht auf Anhieb (1996) in die Foerderung aufgenommen werden. Im November 1997 wurden von der EU-Kommission dann kurzfristig noch 1,5 Mio ECU an Foerderung bewilligt, mit denen ein aktualisierter Projektvorschlag realisiert werden kann. Bereits Mitte 1997 wurde ein kleineres Vorhaben bewilligt, das unter Federfuehrung von Chalmers Industriteknik (CIT) in Schweden beantragt worden war und das vor allem dem Technologietransfer dient. (orig.)

  7. Preliminary Feasibility Study on Application of Very Large Scale-Photovoltaic Power Generation in China

    Institute of Scientific and Technical Information of China (English)

    Hu Xuehao; Zhou Xiaoxin; Bai Xiaomin; Zhang Wentao

    2005-01-01

    Solar energy photovoltaic power generation is hopeful to be applied in a large amount and possesses a certain proportion in the structure of energy in the future. In this paper, based on the forecasting of electric load demand and energy structure of power generation in the middle of 21century, the pictures of VLS-PV power generation is composed, the operation characteristic of VLS-PV power generation and the adaptability of electric power grid for it is analyzed, the ways for transmitting large amount of PV power and the economic and technical bottlenecks for applying VLS-PV power generation are discussed. Finally, the steps and suggestions for developing VLS-PV power generation and its electric power system in China are proposed.

  8. Creating and Using Large Monolingual Parallel Corpora for Sentential Paraphrase Generation

    NARCIS (Netherlands)

    Wubben, S.; Bosch, A.P.J. van den; Krahmer, E.J.

    2014-01-01

    In this paper we investigate the automatic generation of paraphrases by using machine translation techniques. Three contributions we make are the construction of a large paraphrase corpus for English and Dutch, a re-ranking heuristic to use machine translation for paraphrase generation and a proper

  9. A Statistical Model for Hourly Large-Scale Wind and Photovoltaic Generation in New Locations

    DEFF Research Database (Denmark)

    Ekstrom, Jussi; Koivisto, Matti Juhani; Mellin, Ilkka

    2017-01-01

    The analysis of large-scale wind and photovoltaic (PV) energy generation is of vital importance in power systems where their penetration is high. This paper presents a modular methodology to assess the power generation and volatility of a system consisting of both PV plants (PVPs) and wind power ...

  10. Reconstruction of large mandibular defects using autologous tissues generated from in vivo bioreactors

    NARCIS (Netherlands)

    Tatara, A.M.; Shah, S.R.; Demian, N.; Ho, T.; Shum, J.; Beucken, J.J.J.P van den; Jansen, J.A.; Wong, M.E.; Mikos, A.G.

    2016-01-01

    Reconstruction of large mandibular defects is clinically challenging due to the need for donor tissue of appropriate shape and volume to facilitate high fidelity repair. In order to generate large vascularized tissues of custom geometry, bioreactors were implanted against the rib periosteum of 3-4ye

  11. Reconstruction of large mandibular defects using autologous tissues generated from in vivo bioreactors

    NARCIS (Netherlands)

    Tatara, A.M.; Shah, S.R.; Demian, N.; Ho, T.; Shum, J.; Beucken, J.J.J.P van den; Jansen, J.A.; Wong, M.E.; Mikos, A.G.

    2016-01-01

    Reconstruction of large mandibular defects is clinically challenging due to the need for donor tissue of appropriate shape and volume to facilitate high fidelity repair. In order to generate large vascularized tissues of custom geometry, bioreactors were implanted against the rib periosteum of

  12. Reconstruction of large mandibular defects using autologous tissues generated from in vivo bioreactors.

    Science.gov (United States)

    Tatara, Alexander M; Shah, Sarita R; Demian, Nagi; Ho, Tang; Shum, Jonathan; van den Beucken, Jeroen J J P; Jansen, John A; Wong, Mark E; Mikos, Antonios G

    2016-11-01

    Reconstruction of large mandibular defects is clinically challenging due to the need for donor tissue of appropriate shape and volume to facilitate high fidelity repair. In order to generate large vascularized tissues of custom geometry, bioreactors were implanted against the rib periosteum of 3-4year-old sheep for nine weeks. Bioreactors were filled with either morcellized autologous bone, synthetic ceramic particles, or a combination thereof. Tissues generated within synthetic graft-filled bioreactors were transferred into a large right-sided mandibular angle defect as either avascular grafts (n=3) or vascularized free flaps (n=3). After twelve additional weeks, reconstructed mandibular angles were harvested and compared to contralateral control angles. Per histologic and radiologic evaluation, a greater amount of mineralized tissue was generated in bioreactors filled with autologous graft although the quality of viable bone was not significantly different between groups. Genetic analyses of soft tissue surrounding bioreactor-generated tissues demonstrated similar early and late stage osteogenic biomarker expression (Runx2 and Osteocalcin) between the bioreactors and rib periosteum. Although no significant differences between the height of reconstructed and control mandibular angles were observed, the reconstructed mandibles had decreased bone volume. There were no differences between mandibles reconstructed with bioreactor-generated tissues transferred as flaps or grafts. Tissues used for mandibular reconstruction demonstrated integration with native bone as well as evidence of remodeling. In this study, we have demonstrated that synthetic scaffolds are sufficient to generate large volumes of mineralized tissue in an in vivo bioreactor for mandibular reconstruction. A significant clinical challenge in craniofacial surgery is the reconstruction of large mandibular defects. In this work, we demonstrated that vascularized tissues of large volume and custom geometry

  13. Generation of Large-Scale Magnetic Fields by Small-Scale Dynamo in Shear Flows.

    Science.gov (United States)

    Squire, J; Bhattacharjee, A

    2015-10-23

    We propose a new mechanism for a turbulent mean-field dynamo in which the magnetic fluctuations resulting from a small-scale dynamo drive the generation of large-scale magnetic fields. This is in stark contrast to the common idea that small-scale magnetic fields should be harmful to large-scale dynamo action. These dynamos occur in the presence of a large-scale velocity shear and do not require net helicity, resulting from off-diagonal components of the turbulent resistivity tensor as the magnetic analogue of the "shear-current" effect. Given the inevitable existence of nonhelical small-scale magnetic fields in turbulent plasmas, as well as the generic nature of velocity shear, the suggested mechanism may help explain the generation of large-scale magnetic fields across a wide range of astrophysical objects.

  14. Voltage Control of Distribution Network with a Large Penetration of Photovoltaic Generations using FACTS Devices

    Science.gov (United States)

    Kondo, Taro; Baba, Jumpei; Yokoyama, Akihiko

    In recent years, there is a great deal of interest in distributed generations from viewpoints of environmental problem and energy saving measure. Thus, a lot of distributed generators will be connected to the distribution network in the future. However, increase of distributed generators, which convert natural energy into electric energy, is concerned on their adverse effects on distribution network. Therefore, control of distribution networks using Flexible AC Transmission System (FACTS) devices is considered in order to adjust the voltage profile, and as a result more distributed generations can be installed into the networks. In this paper, four types of FACTS devices, Static Synchronous Compensator (STATCOM), Static Synchronous Series Compensator (SSSC), Unified Power Flow Controller (UPFC) and self-commutated Back-To-Back converter (BTB), are analyzed by comparison of required minimum capacity of the inverters in a residential distribution network with a large penetration of photovoltaic generations.

  15. Costing Generated Runtime Execution Plans for Large-Scale Machine Learning Programs

    OpenAIRE

    Boehm, Matthias

    2015-01-01

    Declarative large-scale machine learning (ML) aims at the specification of ML algorithms in a high-level language and automatic generation of hybrid runtime execution plans ranging from single node, in-memory computations to distributed computations on MapReduce (MR) or similar frameworks like Spark. The compilation of large-scale ML programs exhibits many opportunities for automatic optimization. Advanced cost-based optimization techniques require---as a fundamental precondition---an accurat...

  16. System Dynamics Simulation of Large-Scale Generation System for Designing Wind Power Policy in China

    Directory of Open Access Journals (Sweden)

    Linna Hou

    2015-01-01

    Full Text Available This paper focuses on the impacts of renewable energy policy on a large-scale power generation system, including thermal power, hydropower, and wind power generation. As one of the most important clean energy, wind energy has been rapidly developed in the world. But in recent years there is a serious waste of wind power equipment and investment in China leading to many problems in the industry from wind power planning to its integration. One way overcoming the difficulty is to analyze the influence of wind power policy on a generation system. This paper builds a system dynamics (SD model of energy generation to simulate the results of wind energy generation policies based on a complex system. And scenario analysis method is used to compare the effectiveness and efficiency of these policies. The case study shows that the combinations of lower portfolio goal and higher benchmark price and those of higher portfolio goal and lower benchmark price have large differences in both effectiveness and efficiency. On the other hand, the combinations of uniformly lower or higher portfolio goal and benchmark price have similar efficiency, but different effectiveness. Finally, an optimal policy combination can be chosen on the basis of policy analysis in the large-scale power system.

  17. NETMORPH: a framework for the stochastic generation of large scale neuronal networks with realistic neuron morphologies

    NARCIS (Netherlands)

    Koene, R.A.; Tijms, B.; van Hees, P.; Postma, F.; de Ridder, A.; Ramakers, G.J.A.; van Pelt, J.; van Ooyen, A.

    2009-01-01

    We present a simulation framework, called NETMORPH, for the developmental generation of 3D large-scale neuronal networks with realistic neuron morphologies. In NETMORPH, neuronal morphogenesis is simulated from the perspective of the individual growth cone. For each growth cone in a growing axonal o

  18. Scott correction for large atoms and molecules in a self-generated magnetic field

    DEFF Research Database (Denmark)

    Erdös, Laszlo; Fournais, Søren; Solovej, Jan Philip

    2012-01-01

    We consider a large neutral molecule with total nuclear charge $Z$ in non-relativistic quantum mechanics with a self-generated classical electromagnetic field. To ensure stability, we assume that $Z\\al^2\\le \\kappa_0$ for a sufficiently small $\\kappa_0$, where $\\al$ denotes the fine structure...

  19. Scott correction for large atoms and molecules in a self-generated magnetic field

    DEFF Research Database (Denmark)

    Erdös, Laszlo; Fournais, Søren; Solovej, Jan Philip

    2012-01-01

    We consider a large neutral molecule with total nuclear charge $Z$ in non-relativistic quantum mechanics with a self-generated classical electromagnetic field. To ensure stability, we assume that $Z\\al^2\\le \\kappa_0$ for a sufficiently small $\\kappa_0$, where $\\al$ denotes the fine structure...

  20. Two methods for estimating limits to large-scale wind power generation.

    Science.gov (United States)

    Miller, Lee M; Brunsell, Nathaniel A; Mechem, David B; Gans, Fabian; Monaghan, Andrew J; Vautard, Robert; Keith, David W; Kleidon, Axel

    2015-09-08

    Wind turbines remove kinetic energy from the atmospheric flow, which reduces wind speeds and limits generation rates of large wind farms. These interactions can be approximated using a vertical kinetic energy (VKE) flux method, which predicts that the maximum power generation potential is 26% of the instantaneous downward transport of kinetic energy using the preturbine climatology. We compare the energy flux method to the Weather Research and Forecasting (WRF) regional atmospheric model equipped with a wind turbine parameterization over a 10(5) km2 region in the central United States. The WRF simulations yield a maximum generation of 1.1 We⋅m(-2), whereas the VKE method predicts the time series while underestimating the maximum generation rate by about 50%. Because VKE derives the generation limit from the preturbine climatology, potential changes in the vertical kinetic energy flux from the free atmosphere are not considered. Such changes are important at night when WRF estimates are about twice the VKE value because wind turbines interact with the decoupled nocturnal low-level jet in this region. Daytime estimates agree better to 20% because the wind turbines induce comparatively small changes to the downward kinetic energy flux. This combination of downward transport limits and wind speed reductions explains why large-scale wind power generation in windy regions is limited to about 1 We⋅m(-2), with VKE capturing this combination in a comparatively simple way.

  1. A simple biosynthetic pathway for large product generation from small substrate amounts

    Science.gov (United States)

    Djordjevic, Marko; Djordjevic, Magdalena

    2012-10-01

    A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways.

  2. Application of Load Compensation in Voltage Controllers of Large Generators in the Polish Power Grid

    Directory of Open Access Journals (Sweden)

    Bogdan Sobczak

    2014-03-01

    Full Text Available The Automatic Voltage Regulator normally controls the generator stator terminal voltage. Load compensation is used to control the voltage which is representative of the voltage at a point either within or external to the generator. In the Polish Power Grid (PPG compensation is ready to use in every AVR of a large generator, but it is utilized only in the case of generators operating at the same medium voltage buses. It is similar as in most European Power Grids. The compensator regulating the voltage at a point beyond the machine terminals has significant advantages in comparison to the slower secondary Voltage and Reactive Power Control System (ARNE1. The compensation stiffens the EHV grid, which leads to improved voltage quality in the distribution grid. This effect may be particularly important in the context of the dynamic development of wind and solar energy.

  3. Long term reliability and machine operation diagnosis with fiber optic sensors at large turbine generators

    Science.gov (United States)

    Bosselmann, T.; Strack, S.; Villnow, M.; Weidner, J. R.; Willsch, M.

    2013-05-01

    The increasing quantity of renewable energy in electric power generation leads to a higher flexibility in the operation of conventional power plants. The turbo generator has to face the influence of frequent start-stop-operation on thermal movement and vibration of the stator end windings. Large indirect cooled turbo generators have been equipped with FBG strain and temperature sensors to monitor the influence of peak load operation. Fiber optic accelerometers measure the vibration of the end windings at several turbine generators since many years of operation. The long term reliability of fiber optic vibration, temperature and strain sensors has been successfully proved during years of online operation. The analysis of these data in correlation to significant operation parameter lead to important diagnostic information.

  4. Processing large sensor data sets for safeguards : the knowledge generation system.

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Maikel A.; Smartt, Heidi Anne; Matthews, Robert F.

    2012-04-01

    Modern nuclear facilities, such as reprocessing plants, present inspectors with significant challenges due in part to the sheer amount of equipment that must be safeguarded. The Sandia-developed and patented Knowledge Generation system was designed to automatically analyze large amounts of safeguards data to identify anomalous events of interest by comparing sensor readings with those expected from a process of interest and operator declarations. This paper describes a demonstration of the Knowledge Generation system using simulated accountability tank sensor data to represent part of a reprocessing plant. The demonstration indicated that Knowledge Generation has the potential to address several problems critical to the future of safeguards. It could be extended to facilitate remote inspections and trigger random inspections. Knowledge Generation could analyze data to establish trust hierarchies, to facilitate safeguards use of operator-owned sensors.

  5. ASP - Grid connections of large power generating units; ASP - Anslutning av stoerre produktionsanlaeggningar till elnaetet

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Aake; Larsson, Richard [Vattenfall Power Consultants, Stockholm (Sweden)

    2006-12-15

    Grid connections of large power generating units normally require more detailed studies compared to small single units. The required R and D-level depends on the specific characteristics of the production units and the connecting grid. An inquiry for a grid connection will raise questions for the grid owner regarding transmission capability, losses, fault currents, relay protection, dynamic stability etc. Then only a few larger wind farms have been built, the experiences from these types of grid connections are limited and for that reason it can be difficult to identify issues appropriate for further studies. To ensure that electric power generating units do not have unacceptable impact on the grid, directions from the Swedish TSO (Svenska Kraftnaet) have been stated. The directions deal, for example, with power generation in specific ranges of voltage level and frequency and the possibility to remain connected to the grid when different faults occur. The requirements and the consequences of these directions are illustrated. There are three main issues that should be considered: Influence on the power flow from generating units regarding voltage level, currents, losses etc.; Different types of electric systems in generating units contribute to different levels of fault currents. For that reason the resulting fault current levels have to be studied; It is required that generating units should remain connected to the grid at different modes of operation and faults. These modes have to be verified. Load flow and dynamic studies normally demand computer models. Comprehensive models, for instance of wind farms, can bee difficult to design and normally large computer capacity is required. Therefore simplified methods to perform relevant studies are described. How to model an electric power generating unit regarding fault currents and dynamic stability is described. An inquiry for a grid connection normally brings about a discussion concerning administration. To make it

  6. Generation of large-scale magnetic fields from inflation in teleparallelism

    CERN Document Server

    Bamba, Kazuharu; Luo, Ling-Wei

    2012-01-01

    We explore the generation of large-scale magnetic fields from inflation in teleparallelism, in which the gravitational theory is described by the torsion scalar instead of the scalar curvature in general relativity. In particular, we examine the case that the conformal invariance of the electromagnetic field during inflation is broken by a non-minimal gravitational coupling between the torsion scalar and the electromagnetic field. It is shown that for a power-law type coupling, the magnetic field on 1Mpc scale with its strength of $\\sim 10^{-9}$G at the present time can be generated.

  7. Generation of large-scale magnetic fields from inflation in teleparallelism

    Energy Technology Data Exchange (ETDEWEB)

    Bamba, Kazuharu [Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Geng, Chao-Qiang; Luo, Ling-Wei, E-mail: bamba@kmi.nagoya-u.ac.jp, E-mail: geng@phys.nthu.edu.tw, E-mail: d9622508@oz.nthu.edu.tw [Department of Physics, National Tsing Hua University, Hsinchu, 300, Taiwan (China)

    2012-10-01

    We explore the generation of large-scale magnetic fields from inflation in teleparallelism, in which the gravitational theory is described by the torsion scalar instead of the scalar curvature in general relativity. In particular, we examine the case that the conformal invariance of the electromagnetic field during inflation is broken by a non-minimal gravitational coupling between the torsion scalar and the electromagnetic field. It is shown that for a power-law type coupling, the magnetic field on 1 Mpc scale with its strength of ∼ 10{sup −9} G at the present time can be generated.

  8. Scheduling of power generation a large-scale mixed-variable model

    CERN Document Server

    Prékopa, András; Strazicky, Beáta; Deák, István; Hoffer, János; Németh, Ágoston; Potecz, Béla

    2014-01-01

    The book contains description of a real life application of modern mathematical optimization tools in an important problem solution for power networks. The objective is the modelling and calculation of optimal daily scheduling of power generation, by thermal power plants,  to satisfy all demands at minimum cost, in such a way that the  generation and transmission capacities as well as the demands at the nodes of the system appear in an integrated form. The physical parameters of the network are also taken into account. The obtained large-scale mixed variable problem is relaxed in a smart, practical way, to allow for fast numerical solution of the problem.

  9. PMm2: large photomultipliers and innovative electronics for the next-generation neutrino experiments

    CERN Document Server

    Genolini, B; Blin, S; Campagne, J -E; Combettes, B; Conforti, S; De-haine, A -G; Duchesneau, D; Dulucq, F; Dumont-Dayot, N; Favier, J; Fouché, F; Hermel, R; de La Taille, C; Martin-Chassard, G; Trung, T Nguyen; Périnet, C; Peyré, J; Pouthas, J; Raux, L; Rindel, E; Rosier, P; Tassan-Viol, J; Wei, W; Zghiche, A

    2008-01-01

    The next generation of proton decay and neutrino experiments, the post-SuperKamiokande detectors as those that will take place in megaton size water tanks, will require very large surfaces of photodetection and a large volume of data. Even with large hemispherical photomultiplier tubes, the expected number of channels should reach hundreds of thousands. A funded R&D program to implement a solution is presented here. The very large surface of photodetection is segmented in macro pixels made of 16 hemispherical (12 inches) photomultiplier tubes connected to an autonomous front-end which works on a triggerless data acquisition mode. The expected data transmission rate is 5 Mb/s per cable, which can be achieved with existing techniques. This architecture allows to reduce considerably the cost and facilitate the industrialization. This document presents the simulations and measurements which define the requirements for the photomultipliers and the electronics. A proto-type of front-end electronics was successf...

  10. Tellurite suspended nanowire surrounded with large holes for single-mode SC and THG generations

    Science.gov (United States)

    Liao, Meisong; Qin, Guanshi; Yan, Xin; Chaudhari, Chitrarekha; Suzuki, Takenobu; Ohishi, Yasutake

    2011-05-01

    For a suspended nanowire, the holes surrounding the core are expected to be as large as possible to propagate the light at wavelengths as long as possible. However, the fabrication of nanowire surrounded with large holes is still a challenge so far. In this paper, a method which involves pumping positive pressure of nitrogen gas in both the cane fabrication and fiber-drawing processes, is proposed. A suspended nanowire, with a core diameter of 480 nm and an unprecedented large diameter ratio of holey region to core (DRHC) of at least 62, is fabricated in the length of several hundred meters. Owing to the large holes, the confinement loss of the suspended nanowire is insignificant when the wavelength of light propagated in it is 1700 nm. Additionally, the tube-shaped glass cladding of the suspended nanowire shifts the singlemode cutoff wavelength to 810 nm, which is much shorter than the cutoff wavelength, 1070 nm, of a naked nanowire with the same diameter. A single-mode supercontinuum (SC) generation covering a wavelength range of 900-1600 nm is obtained under 1064 nm pump pulse with the peak power as low as 24 W. A single-mode third harmonic generation (THG) is observed by this nanowire under the pump of a 1557 nm femtosecond fiber laser. This work indicates that the suspended nanowire with large holes can provide high nonlinearity together with single-mode propagation, which leads to interesting applications in compact nonlinear devices.

  11. How large customer direct power transaction mode give consideration to power generation cleaning and power saving

    Science.gov (United States)

    Liu, Yu; Zeng, Ming; Liu, Wei; Li, Ran

    2017-05-01

    The so-called Large Customers' Direct Power Transaction, refers to the mode that the users on high voltage level, or being seized of hold the large power or independent power distribution, have the qualification of purchasing electricity directly from the generation companies and pay reasonable electricity transmission and distribution fee to the power network enterprises because the transaction is through its transmission channel. The Direct Purchase promotes the marketization level of electricity trading, but there are some problems in its developing process, especially whether promotes the green optimal allocation of power resources, this paper aims to explore the solution.

  12. Visualization of the Flux Rope Generation Process Using Large Quantities of MHD Simulation Data

    Directory of Open Access Journals (Sweden)

    Y Kubota

    2013-03-01

    Full Text Available We present a new concept of analysis using visualization of large quantities of simulation data. The time development of 3D objects with high temporal resolution provides the opportunity for scientific discovery. We visualize large quantities of simulation data using the visualization application 'Virtual Aurora' based on AVS (Advanced Visual Systems and the parallel distributed processing at "Space Weather Cloud" in NICT based on Gfarm technology. We introduce two results of high temporal resolution visualization: the magnetic flux rope generation process and dayside reconnection using a system of magnetic field line tracing.

  13. Generation of weakly nonlinear nonhydrostatic internal tides over large topography: a multi-modal approach

    Directory of Open Access Journals (Sweden)

    R. Maugé

    2008-03-01

    Full Text Available A set of evolution equations is derived for the modal coefficients in a weakly nonlinear nonhydrostatic internal-tide generation problem. The equations allow for the presence of large-amplitude topography, e.g. a continental slope, which is formally assumed to have a length scale much larger than that of the internal tide. However, comparison with results from more sophisticated numerical models show that this restriction can in practice be relaxed. It is shown that a topographically induced coupling between modes occurs that is distinct from nonlinear coupling. Nonlinear effects include the generation of higher harmonics by reflection from boundaries, i.e. steeper tidal beams at frequencies that are multiples of the basic tidal frequency. With a seasonal thermocline included, the model is capable of reproducing the phenomenon of local generation of internal solitary waves by a tidal beam impinging on the seasonal thermocline.

  14. Size Reduction Techniques for Large Scale Permanent Magnet Generators in Wind Turbines

    Science.gov (United States)

    Khazdozian, Helena; Hadimani, Ravi; Jiles, David

    2015-03-01

    Increased wind penetration is necessary to reduce U.S. dependence on fossil fuels, combat climate change and increase national energy security. The U.S Department of Energy has recommended large scale and offshore wind turbines to achieve 20% wind electricity generation by 2030. Currently, geared doubly-fed induction generators (DFIGs) are typically employed in the drivetrain for conversion of mechanical to electrical energy. Yet, gearboxes account for the greatest downtime of wind turbines, decreasing reliability and contributing to loss of profit. Direct drive permanent magnet generators (PMGs) offer a reliable alternative to DFIGs by eliminating the gearbox. However, PMGs scale up in size and weight much more rapidly than DFIGs as rated power is increased, presenting significant challenges for large scale wind turbine application. Thus, size reduction techniques are needed for viability of PMGs in large scale wind turbines. Two size reduction techniques are presented. It is demonstrated that 25% size reduction of a 10MW PMG is possible with a high remanence theoretical permanent magnet. Additionally, the use of a Halbach cylinder in an outer rotor PMG is investigated to focus magnetic flux over the rotor surface in order to increase torque. This work was supported by the National Science Foundation under Grant No. 1069283 and a Barbara and James Palmer Endowment at Iowa State University.

  15. HiQuant: Rapid Postquantification Analysis of Large-Scale MS-Generated Proteomics Data.

    Science.gov (United States)

    Bryan, Kenneth; Jarboui, Mohamed-Ali; Raso, Cinzia; Bernal-Llinares, Manuel; McCann, Brendan; Rauch, Jens; Boldt, Karsten; Lynn, David J

    2016-06-01

    Recent advances in mass-spectrometry-based proteomics are now facilitating ambitious large-scale investigations of the spatial and temporal dynamics of the proteome; however, the increasing size and complexity of these data sets is overwhelming current downstream computational methods, specifically those that support the postquantification analysis pipeline. Here we present HiQuant, a novel application that enables the design and execution of a postquantification workflow, including common data-processing steps, such as assay normalization and grouping, and experimental replicate quality control and statistical analysis. HiQuant also enables the interpretation of results generated from large-scale data sets by supporting interactive heatmap analysis and also the direct export to Cytoscape and Gephi, two leading network analysis platforms. HiQuant may be run via a user-friendly graphical interface and also supports complete one-touch automation via a command-line mode. We evaluate HiQuant's performance by analyzing a large-scale, complex interactome mapping data set and demonstrate a 200-fold improvement in the execution time over current methods. We also demonstrate HiQuant's general utility by analyzing proteome-wide quantification data generated from both a large-scale public tyrosine kinase siRNA knock-down study and an in-house investigation into the temporal dynamics of the KSR1 and KSR2 interactomes. Download HiQuant, sample data sets, and supporting documentation at http://hiquant.primesdb.eu .

  16. Memory Effects in Turbulent Dynamo Generation and Propagation of Large Scale Magnetic Field

    CERN Document Server

    Fedotov, S; Zubarev, A; Fedotov, Sergei; Ivanov, Alexey; Zubarev, Andrey

    2001-01-01

    We are concerned with large scale magnetic field dynamo generation and propagation of magnetic fronts in turbulent electrically conducting fluids. An effective equation for the large scale magnetic field is developed here that takes into account the finite correlation times of the turbulent flow. This equation involves the memory integrals corresponding to the dynamo source term describing the alpha-effect and turbulent transport of magnetic field. We find that the memory effects can drastically change the dynamo growth rate, in particular, non-local turbulent transport might increase the growth rate several times compared to the conventional gradient transport expression. Moreover, the integral turbulent transport term leads to a large decrease of the speed of magnetic front propagation.

  17. Measurement and prediction of broadband noise from large horizontal axis wind turbine generators

    Science.gov (United States)

    Grosveld, F. W.; Shepherd, K. P.; Hubbard, H. H.

    1995-01-01

    A method is presented for predicting the broadband noise spectra of large wind turbine generators. It includes contributions from such noise sources as the inflow turbulence to the rotor, the interactions between the turbulent boundary layers on the blade surfaces with their trailing edges and the wake due to a blunt trailing edge. The method is partly empirical and is based on acoustic measurements of large wind turbines and airfoil models. Spectra are predicted for several large machines including the proposed MOD-5B. Measured data are presented for the MOD-2, the WTS-4, the MOD-OA, and the U.S. Windpower Inc. machines. Good agreement is shown between the predicted and measured far field noise spectra.

  18. Ionospheric plasma disturbances generated by naturally occurring large-scale anomalous heat sources

    Science.gov (United States)

    Pradipta, Rezy; Lee, Min-Chang; Coster, Anthea J.; Tepley, Craig A.; Sulzer, Michael P.; Gonzalez, Sixto A.

    2017-04-01

    We report the findings from our investigation on the possibility of large-scale anomalous thermal gradients to generate acoustic-gravity waves (AGWs) and traveling ionospheric disturbances (TIDs). In particular, here we consider the case of summer 2006 North American heat wave event as a concrete example of such large-scale natural thermal gradients. This special scenario of AGW/TID generation was formulated based on the results of our experiments at the Arecibo Observatory in July 2006, followed by a systematic monitoring/surveillance of total electron content (TEC) fluctuations over North America in 2005-2007 using the MIT Haystack Observatory's Madrigal database. The data from our Arecibo experiments indicate a continual occurrence of intense AGW/TID over the Caribbean on 21-24 July 2006, and the Madrigal TEC data analysis shows that the overall level of TID activity over North America had increased by ∼0.2 TECU during the summer 2006 heat wave event. Our proposed scenario is in agreement with these empirical observations, and is generally consistent with a number of past ionospheric HF heating experiments related to AGW/TID generation.

  19. A top-down model to generate ensembles of runoff from a large number of hillslopes

    Directory of Open Access Journals (Sweden)

    P. R. Furey

    2013-09-01

    Full Text Available We hypothesize that total hillslope water loss for a rainfall–runoff event is inversely related to a function of a lognormal random variable, based on basin- and point-scale observations taken from the 21 km2 Goodwin Creek Experimental Watershed (GCEW in Mississippi, USA. A top-down approach is used to develop a new runoff generation model both to test our physical-statistical hypothesis and to provide a method of generating ensembles of runoff from a large number of hillslopes in a basin. The model is based on the assumption that the probability distributions of a runoff/loss ratio have a space–time rescaling property. We test this assumption using streamflow and rainfall data from GCEW. For over 100 rainfall–runoff events, we find that the spatial probability distributions of a runoff/loss ratio can be rescaled to a new distribution that is common to all events. We interpret random within-event differences in runoff/loss ratios in the model to arise from soil moisture spatial variability. Observations of water loss during events in GCEW support this interpretation. Our model preserves water balance in a mean statistical sense and supports our hypothesis. As an example, we use the model to generate ensembles of runoff at a large number of hillslopes for a rainfall–runoff event in GCEW.

  20. A top-down model to generate ensembles of runoff from a large number of hillslopes

    Science.gov (United States)

    Furey, P. R.; Gupta, V. K.; Troutman, B. M.

    2013-09-01

    We hypothesize that total hillslope water loss for a rainfall-runoff event is inversely related to a function of a lognormal random variable, based on basin- and point-scale observations taken from the 21 km2 Goodwin Creek Experimental Watershed (GCEW) in Mississippi, USA. A top-down approach is used to develop a new runoff generation model both to test our physical-statistical hypothesis and to provide a method of generating ensembles of runoff from a large number of hillslopes in a basin. The model is based on the assumption that the probability distributions of a runoff/loss ratio have a space-time rescaling property. We test this assumption using streamflow and rainfall data from GCEW. For over 100 rainfall-runoff events, we find that the spatial probability distributions of a runoff/loss ratio can be rescaled to a new distribution that is common to all events. We interpret random within-event differences in runoff/loss ratios in the model to arise from soil moisture spatial variability. Observations of water loss during events in GCEW support this interpretation. Our model preserves water balance in a mean statistical sense and supports our hypothesis. As an example, we use the model to generate ensembles of runoff at a large number of hillslopes for a rainfall-runoff event in GCEW.

  1. Large Eddy Simulation of New Vortex Generator Enhancing Heat Exchange of Solar Energy

    Institute of Scientific and Technical Information of China (English)

    WEN Juan; YANG Li; QI Cheng-ying

    2009-01-01

    This paper put forward a new-type vortex generator enhancing heat exchange of solar air-drier and air-heater on the gas side,and investigated the mechanism of heat transfer enhancement and drag reduction by the influence of vortex generators on the coherent structure of turbulent boundary layer.The flow and heat transfer characteristics of rectangle channel with bevel-cut half-elliptical column vortex generators were obtained using large eddy simulation (LES) and the hydromechanics software FLUENT6.3.The instantaneous proper-ties of velocity,temperature and pressure in channel were gained.The coherent structure of turbulent boundary layer flow was showed, and the characteristic of vortex induced by inclined-cut semi-ellipse vortex generator and its influence on turbulent coherent structure were analyzed.And the effect mechanism of turbulent coherent structure on flow field,pressure field and temperature field was discussed.Based on the results,the heat trans-fer coefficient and drag reduction of the new vortex generator with different pitch angles were compared.Some-times.the coherent effects of the increased wall heat transfer and the decreased skin friction do not satisfy theReynolds analogy.The turbulent coherent structure can be controlled through the geometry of the vortex gener-ator.so the heat transfer and drag reduction can also be controlled.Then we can seek suitable form of vortex generator and structure parameters.in order to achieve the enhanced heat transfer and flow of drag reduction in the solar air-heater and solar air-drier.

  2. Power Electronic Drives, Controls, and Electric Generators for Large Wind Turbines - An Overview

    DEFF Research Database (Denmark)

    Ma, Ke; Tutelea, L.; Boldea, Ion

    2015-01-01

    Wind represents a major and growing source of renewable energy for the electric power systems. This article provides an overview of state-of-the-art technologies and anticipated developments in the area of power electronic drives, controls, and electric generators for large multi-megawatt wind...... of power electronics, ranging from devices to circuit topologies, and similar matters for electric generators, together with results of optimal design studies are included. It is shown that the individual power rating of wind turbines has increased over the years, and technologies required to reach...... turbine systems. The principal components employed in a turbine for energy conversion from wind to electricity are described, and the main solutions that are commercially available are briefly reviewed. The specific issues of complex mission profiles, power codes, and reliability are discussed. Topics...

  3. Large-scale, realistic laboratory modeling of M2 internal tide generation at the Luzon Strait

    CERN Document Server

    Mercier, Matthieu J; Helfrich, Karl; Sommeria, Joël; Viboud, Samuel; Didelle, Henri; Saidi, Sasan; Dauxois, Thierry; Peacock, Thomas

    2015-01-01

    The complex double-ridge system in the Luzon Strait in the South China Sea (SCS) is one of the strongest sources of internal tides in the oceans, associated with which are some of the largest amplitude internal solitary waves on record. An issue of debate, however, has been the specific nature of their generation mechanism. To provide insight, we present the results of a large-scale laboratory experiment performed at the Coriolis platform. The experiment was carefully designed so that the relevant dimensionless parameters, which include the excursion parameter, criticality, Rossby, and Froude numbers, closely matched the ocean scenario. The results advocate that a broad and coherent weakly nonlinear, three-dimensional, M2 internal tide that is shaped by the overall geometry of the double-ridge system is radiated into the South China Sea and subsequently steepens, as opposed to being generated by a particular feature or localized region within the ridge system.

  4. Generation of large-scale vortex dislocations in a three-dimensional wake-type flow

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Numerical study of three-dimensional evolution of wake-type flow and vortex dislocations is performed by using a compact finite diffenence-Fourier spectral method to solve 3-D incompressible Navier-Stokes equations. A local spanwise nonuniformity in momentum defect is imposed on the incoming wake-type flow. The present numerical results have shown that the flow instability leads to three-dimensional vortex streets, whose frequency, phase as well as the strength vary with the span caused by the local nonuniformity. The vortex dislocations are generated in the nonuniform region and the large-scale chain-like vortex linkage structures in the dislocations are shown. The generation and the characteristics of the vortex dislocations are described in detail.

  5. Generating the Infrared Spectra of Large Interstellar Molecules with Density Functional Theory

    Science.gov (United States)

    Bauschlicher, Charles W., Jr.; Arnold, James (Technical Monitor)

    1999-01-01

    It is now possible to compute IR (infrared) spectra of large molecules with an accuracy of 30 per cm, or better, using density function theory. This is true for cations, anions, and neutrals. Thus it possible to generate synthetic IR spectra that can help interpret experimental spectra and fill in for missing experimental data. These synthetic spectra can be used as input into interstellar models. In addition to IR spectra, it is possible to compute energetic properties to help understand which molecules can be formed in the interstellar environment.

  6. A Method for Generating Super Large Fractal Images useful for Decoration Art

    Institute of Scientific and Technical Information of China (English)

    HuajieLIU; JunLUO

    1996-01-01

    Many authors have reported the techniques to iterate nonlinear equations on complex plane,but generally,the size of image calculated by usual VGA style(640×480) is too small to fit the needs for high quality publications or ecorative patterns.We describe a universal method for generating and storing(in *.GIF format)fractal image large enough as you need,such as an image 5000×5000 256-color(25,000,774 bytes≈23.8MB),which can thoroughly display the intricate beauty of fractals.

  7. Generating the Infrared Spectra of Large Interstellar Molecules with Density Functional Theory

    Science.gov (United States)

    Bauschlicher, Charles W., Jr.; Arnold, James (Technical Monitor)

    1999-01-01

    It is now possible to compute IR (infrared) spectra of large molecules with an accuracy of 30 per cm, or better, using density function theory. This is true for cations, anions, and neutrals. Thus it possible to generate synthetic IR spectra that can help interpret experimental spectra and fill in for missing experimental data. These synthetic spectra can be used as input into interstellar models. In addition to IR spectra, it is possible to compute energetic properties to help understand which molecules can be formed in the interstellar environment.

  8. Large Deviation Generating Function for Currents in the Pauli-Fierz Model

    Science.gov (United States)

    de Roeck, Wojciech

    We consider a finite quantum system coupled to quasifree thermal reservoirs at different temperatures. We construct the statistics of energy transport between the reservoirs and we show that the corresponding large deviation generating function exists and it is analytic on a compact set. This result is valid for small coupling and exponentially decaying reservoir correlation functions. Our technique consists of a diagrammatic expansion that uses the Markovian limit of the system as a reference. As a corollary, we derive the Gallavotti-Cohen fluctuation relation for the entropy production.

  9. Rucio - The next generation large scale distributed system for ATLAS Data Management

    CERN Document Server

    Beermann, T; The ATLAS collaboration; Lassnig, M; Barisits, M; Vigne, R; Serfon, C; Stewart, G A; Goossens, L; Nairz, A; Molfetas, A

    2014-01-01

    Rucio is the next-generation Distributed Data Management (DDM) system benefiting from recent advances in cloud and "Big Data" computing to address the ATLAS experiment scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 150 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will deal with these issues by relying on new technologies to ensure system scalability, address new user requirements and employ a new automation framework to reduce operational overheads.

  10. Prediction of broadband noise from large horizontal axis wind turbine generators

    Science.gov (United States)

    Grosveld, F. W.

    1984-01-01

    A method is presented for predicting the broadband noise spectra of large horizontal axis wind turbine generators. It includes contributions from such noise sources as the inflow turbulence to the rotor, the interactions between the turbulent boundary layers on the blade surfaces with their trailing edges and the wake due to a blunt trailing edge. The method is partly empirical and is based on acoustic measurements of large wind turbines and airfoil models. The predicted frequency spectra are compared with measured data from several machines including the MOD-OA, the MOD-2, the WTS-4 and the U.S. Wind-power Inc. machine. Also included is a broadband noise prediction for the proposed MOD-5B. The significance of the effects of machine size, power output, trailing edge bluntness and distance to the receiver is illustrated. Good agreement is obtained between the predicted and measured far field noise spectra.

  11. Field experiments of NR-PSS for large synchronous generators on a 300MW machine in Baishan Hydro Plant

    Institute of Scientific and Technical Information of China (English)

    LU Qiang; MEI ShengWei; ZHENG ShaoMing

    2007-01-01

    To verify the performance of NR-PSS (Nonlinear Robust Power System Stabilizer) for large synchronous generators, field experiments were carried out on a 300 MW generator in Baishan Hydro Plant of Northeast China Power Grid. The experiment results show that NR-PSS can improve the generator damping and enhance system stability remarkably.

  12. Generation of Diffuse Large Volume Plasma by an Ionization Wave from a Plasma Jet

    Science.gov (United States)

    Laroussi, Mounir; Razavi, Hamid

    2015-09-01

    Low temperature plasma jets emitted in ambient air are the product of fast ionization waves that are guided within a channel of a gas flow, such as helium. This guided ionization wave can be transmitted through a dielectric material and under some conditions can ignite a discharge behind the dielectric material. Here we present a novel way to produce large volume diffuse low pressure plasma inside a Pyrex chamber that does not have any electrodes or electrical energy directly applied to it. The diffuse plasma is ignited inside the chamber by a plasma jet located externally to the chamber and that is physically and electrically unconnected to the chamber. Instead, the plasma jet is just brought in close proximity to the external wall/surface of the chamber or to a dielectric tubing connected to the chamber. The plasma thus generated is diffuse, large volume and with physical and chemical characteristics that are different than the external plasma jet that ignited it. So by using a plasma jet we are able to ``remotely'' ignite volumetric plasma under controlled conditions. This novel method of ``remote'' generation of a low pressure, low temperature diffuse plasma can be useful for various applications including material processing and biomedicine.

  13. A Repetitive Nanosecond Pulse Source for Generation of Large Volume Streamer Discharge

    Institute of Scientific and Technical Information of China (English)

    TAO Fengbo; ZHANG Qiaogen; GAO Bo; WANG Hu; LI Zhou

    2008-01-01

    Using a unipolar pulse with the rise time and the pulse duration in the order of microsecond as the primary pulse,a nanosecond pulse with the repetitive frequency of several kilohertz is generated by a spark gap switch.By varying both the inter-pulse duration and the pulse frequency,the voltage recovery rate of the spark gap switch is investigated at different working conditions such as the gas pressure,the gas composition as well as the bias voltage.The results reveal that either increase in gas pressure or addition of SF6 to the air can increase the voltage recovery rate.The effect of gas composition on the voltage recovery rate is discussed based on the transferring and distribution of the residual space charges.The repetitive nanosecond pulse source is also applied to the generation of large volume,and the discharge currents are measured to investigate the effect of pulse repetition rate on the large volume streamer discharge.

  14. Automatic generation of large ensembles for air quality forecasting using the Polyphemus system

    Directory of Open Access Journals (Sweden)

    D. Garaud

    2009-07-01

    Full Text Available This paper describes a method to automatically generate a large ensemble of air quality simulations. This is achieved using the Polyphemus system, which is flexible enough to build various different models. The system offers a wide range of options in the construction of a model: many physical parameterizations, several numerical schemes and different input data can be combined. In addition, input data can be perturbed. In this paper, some 30 alternatives are available for the generation of a model. For each alternative, the options are given a probability, based on how reliable they are supposed to be. Each model of the ensemble is defined by randomly selecting one option per alternative. In order to decrease the computational load, as many computations as possible are shared by the models of the ensemble. As an example, an ensemble of 101 photochemical models is generated and run for the year 2001 over Europe. The models' performance is quickly reviewed, and the ensemble structure is analyzed. We found a strong diversity in the results of the models and a wide spread of the ensemble. It is noteworthy that many models turn out to be the best model in some regions and some dates.

  15. Extensive Recombination Due to Heteroduplexes Generates Large Amounts of Artificial Gene Fragments during PCR

    Science.gov (United States)

    Liu, Jia; Song, Hongshuo; Liu, Donglai; Zuo, Tao; Lu, Fengmin; Zhuang, Hui; Gao, Feng

    2014-01-01

    Artificial recombinants can be generated during PCR when more than two genetically distinct templates coexist in a single PCR reaction. These recombinant amplicons can lead to the false interpretation of genetic diversity and incorrect identification of biological phenotypes that do not exist in vivo. We investigated how recombination between 2 or 35 genetically distinct HIV-1 genomes was affected by different PCR conditions using the parallel allele-specific sequencing (PASS) assay and the next generation sequencing method. In a standard PCR condition, about 40% of amplicons in a PCR reaction were recombinants. The high recombination frequency could be significantly reduced if the number of amplicons in a PCR reaction was below a threshold of 1013–1014 using low thermal cycles, fewer input templates, and longer extension time. Heteroduplexes (each DNA strand from a distinct template) were present at a large proportion in the PCR products when more thermal cycles, more templates, and shorter extension time were used. Importantly, the majority of recombinants were identified in heteroduplexes, indicating that the recombinants were mainly generated through heteroduplexes. Since prematurely terminated extension fragments can form heteroduplexes by annealing to different templates during PCR amplification, recombination has a better chance to occur with samples containing different genomes when the number of amplicons accumulate over the threshold. New technologies are warranted to accurately characterize complex quasispecies gene populations. PMID:25211143

  16. A large volume uniform plasma generator for the experiments of electromagnetic wave propagation in plasma

    Energy Technology Data Exchange (ETDEWEB)

    Yang Min; Li Xiaoping; Xie Kai; Liu Donglin [School of Electronical and Mechanical Engineering, Xidian University, Xi' an Shaanxi 710071 (China); Liu Yanming [School of Telecommunications Engineering, Xidian University, Xi' an Shaanxi 710071 (China)

    2013-01-15

    A large volume uniform plasma generator is proposed for the experiments of electromagnetic (EM) wave propagation in plasma, to reproduce a 'black out' phenomenon with long duration in an environment of the ordinary laboratory. The plasma generator achieves a controllable approximate uniform plasma in volume of 260 mm Multiplication-Sign 260 mm Multiplication-Sign 180 mm without the magnetic confinement. The plasma is produced by the glow discharge, and the special discharge structure is built to bring a steady approximate uniform plasma environment in the electromagnetic wave propagation path without any other barriers. In addition, the electron density and luminosity distributions of plasma under different discharge conditions were diagnosed and experimentally investigated. Both the electron density and the plasma uniformity are directly proportional to the input power and in roughly reverse proportion to the gas pressure in the chamber. Furthermore, the experiments of electromagnetic wave propagation in plasma are conducted in this plasma generator. Blackout phenomena at GPS signal are observed under this system and the measured attenuation curve is of reasonable agreement with the theoretical one, which suggests the effectiveness of the proposed method.

  17. Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR.

    Directory of Open Access Journals (Sweden)

    Jia Liu

    Full Text Available Artificial recombinants can be generated during PCR when more than two genetically distinct templates coexist in a single PCR reaction. These recombinant amplicons can lead to the false interpretation of genetic diversity and incorrect identification of biological phenotypes that do not exist in vivo. We investigated how recombination between 2 or 35 genetically distinct HIV-1 genomes was affected by different PCR conditions using the parallel allele-specific sequencing (PASS assay and the next generation sequencing method. In a standard PCR condition, about 40% of amplicons in a PCR reaction were recombinants. The high recombination frequency could be significantly reduced if the number of amplicons in a PCR reaction was below a threshold of 10(13-10(14 using low thermal cycles, fewer input templates, and longer extension time. Heteroduplexes (each DNA strand from a distinct template were present at a large proportion in the PCR products when more thermal cycles, more templates, and shorter extension time were used. Importantly, the majority of recombinants were identified in heteroduplexes, indicating that the recombinants were mainly generated through heteroduplexes. Since prematurely terminated extension fragments can form heteroduplexes by annealing to different templates during PCR amplification, recombination has a better chance to occur with samples containing different genomes when the number of amplicons accumulate over the threshold. New technologies are warranted to accurately characterize complex quasispecies gene populations.

  18. CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs

    Directory of Open Access Journals (Sweden)

    Djordjevic Marko

    2012-07-01

    Full Text Available Abstract Background CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated sequences is a recently discovered prokaryotic defense system against foreign DNA, including viruses and plasmids. CRISPR cassette is transcribed as a continuous transcript (pre-crRNA, which is processed by Cas proteins into small RNA molecules (crRNAs that are responsible for defense against invading viruses. Experiments in E. coli report that overexpression of cas genes generates a large number of crRNAs, from only few pre-crRNAs. Results We here develop a minimal model of CRISPR processing, which we parameterize based on available experimental data. From the model, we show that the system can generate a large amount of crRNAs, based on only a small decrease in the amount of pre-crRNAs. The relationship between the decrease of pre-crRNAs and the increase of crRNAs corresponds to strong linear amplification. Interestingly, this strong amplification crucially depends on fast non-specific degradation of pre-crRNA by an unidentified nuclease. We show that overexpression of cas genes above a certain level does not result in further increase of crRNA, but that this saturation can be relieved if the rate of CRISPR transcription is increased. We furthermore show that a small increase of CRISPR transcription rate can substantially decrease the extent of cas gene activation necessary to achieve a desired amount of crRNA. Conclusions The simple mathematical model developed here is able to explain existing experimental observations on CRISPR transcript processing in Escherichia coli. The model shows that a competition between specific pre-crRNA processing and non-specific degradation determines the steady-state levels of crRNA and is responsible for strong linear amplification of crRNAs when cas genes are overexpressed. The model further shows how disappearance of only a few pre-crRNA molecules normally present in the cell can lead to a large (two

  19. Z-DNA-forming sequences generate large-scale deletions in mammalian cells.

    Science.gov (United States)

    Wang, Guliang; Christensen, Laura A; Vasquez, Karen M

    2006-02-21

    Spontaneous chromosomal breakages frequently occur at genomic hot spots in the absence of DNA damage and can result in translocation-related human disease. Chromosomal breakpoints are often mapped near purine-pyrimidine Z-DNA-forming sequences in human tumors. However, it is not known whether Z-DNA plays a role in the generation of these chromosomal breakages. Here, we show that Z-DNA-forming sequences induce high levels of genetic instability in both bacterial and mammalian cells. In mammalian cells, the Z-DNA-forming sequences induce double-strand breaks nearby, resulting in large-scale deletions in 95% of the mutants. These Z-DNA-induced double-strand breaks in mammalian cells are not confined to a specific sequence but rather are dispersed over a 400-bp region, consistent with chromosomal breakpoints in human diseases. This observation is in contrast to the mutations generated in Escherichia coli that are predominantly small deletions within the repeats. We found that the frequency of small deletions is increased by replication in mammalian cell extracts. Surprisingly, the large-scale deletions generated in mammalian cells are, at least in part, replication-independent and are likely initiated by repair processing cleavages surrounding the Z-DNA-forming sequence. These results reveal that mammalian cells process Z-DNA-forming sequences in a strikingly different fashion from that used by bacteria. Our data suggest that Z-DNA-forming sequences may be causative factors for gene translocations found in leukemias and lymphomas and that certain cellular conditions such as active transcription may increase the risk of Z-DNA-related genetic instability.

  20. Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy.

    Directory of Open Access Journals (Sweden)

    Corinne Kostic

    Full Text Available Large animal models are an important resource for the understanding of human disease and for evaluating the applicability of new therapies to human patients. For many diseases, such as cone dystrophy, research effort is hampered by the lack of such models. Lentiviral transgenesis is a methodology broadly applicable to animals from many different species. When conjugated to the expression of a dominant mutant protein, this technology offers an attractive approach to generate new large animal models in a heterogeneous background. We adopted this strategy to mimic the phenotype diversity encounter in humans and generate a cohort of pigs for cone dystrophy by expressing a dominant mutant allele of the guanylate cyclase 2D (GUCY2D gene. Sixty percent of the piglets were transgenic, with mutant GUCY2D mRNA detected in the retina of all animals tested. Functional impairment of vision was observed among the transgenic pigs at 3 months of age, with a follow-up at 1 year indicating a subsequent slower progression of phenotype. Abnormal retina morphology, notably among the cone photoreceptor cell population, was observed exclusively amongst the transgenic animals. Of particular note, these transgenic animals were characterized by a range in the severity of the phenotype, reflecting the human clinical situation. We demonstrate that a transgenic approach using lentiviral vectors offers a powerful tool for large animal model development. Not only is the efficiency of transgenesis higher than conventional transgenic methodology but this technique also produces a heterogeneous cohort of transgenic animals that mimics the genetic variation encountered in human patients.

  1. Spontaneous large-scale autolysis in Clostridium acetobutylicum contributes to generation of more spores

    Science.gov (United States)

    Liu, Zhen; Qiao, Kai; Tian, Lei; Zhang, Quan; Liu, Zi-Yong; Li, Fu-Li

    2015-01-01

    Autolysis is a widespread phenomenon in bacteria. In batch fermentation of Clostridium acetobutylicum ATCC 824, there is a spontaneous large-scale autolysis phenomenon with significant decrease of cell density immediately after exponential phase. To unravel the role of autolysis, an autolysin-coding gene, CA_C0554, was disrupted by using ClosTron system to obtain the mutant C. acetobutylicum lyc::int(72). The lower final cell density and faster cell density decrease rate of C. acetobutylicum ATCC 824 than those of C. acetobutylicum lyc::int(72) indicates that CA_C0554 was an important but not the sole autolysin-coding gene responding for the large-scale autolysis. Similar glucose utilization and solvents production but obvious lower cell density of C. acetobutylicum ATCC 824 comparing to C. acetobutylicum lyc::int(72) suggests that lysed C. acetobutylicum ATCC 824 cells were metabolic inactive. On the contrary, the spore density of C. acetobutylicum ATCC 824 is 26.1% higher than that of C. acetobutylicum lyc::int(72) in the final culture broth of batch fermentation. We speculated that spontaneous autolysis of metabolic-inactive cells provided nutrients for the sporulating cells. The present study suggests that one important biological role of spontaneous large-scale autolysis in C. acetobutylicum ATCC 824 batch fermentation is contributing to generation of more spores during sporulation. PMID:26441884

  2. Spontaneous large-scale autolysis in Clostridium acetobutylicum contributes to generation of more spores.

    Science.gov (United States)

    Liu, Zhen; Qiao, Kai; Tian, Lei; Zhang, Quan; Liu, Zi-Yong; Li, Fu-Li

    2015-01-01

    Autolysis is a widespread phenomenon in bacteria. In batch fermentation of Clostridium acetobutylicum ATCC 824, there is a spontaneous large-scale autolysis phenomenon with significant decrease of cell density immediately after exponential phase. To unravel the role of autolysis, an autolysin-coding gene, CA_C0554, was disrupted by using ClosTron system to obtain the mutant C. acetobutylicum lyc::int(72). The lower final cell density and faster cell density decrease rate of C. acetobutylicum ATCC 824 than those of C. acetobutylicum lyc::int(72) indicates that CA_C0554 was an important but not the sole autolysin-coding gene responding for the large-scale autolysis. Similar glucose utilization and solvents production but obvious lower cell density of C. acetobutylicum ATCC 824 comparing to C. acetobutylicum lyc::int(72) suggests that lysed C. acetobutylicum ATCC 824 cells were metabolic inactive. On the contrary, the spore density of C. acetobutylicum ATCC 824 is 26.1% higher than that of C. acetobutylicum lyc::int(72) in the final culture broth of batch fermentation. We speculated that spontaneous autolysis of metabolic-inactive cells provided nutrients for the sporulating cells. The present study suggests that one important biological role of spontaneous large-scale autolysis in C. acetobutylicum ATCC 824 batch fermentation is contributing to generation of more spores during sporulation.

  3. Spontaneous large-scale autolysis in Clostridium acetobutylicum contributes to generation of more spores

    Directory of Open Access Journals (Sweden)

    Zhen eLiu

    2015-09-01

    Full Text Available Autolysis is a widespread phenomenon in bacteria. In batch fermentation of Clostridium acetobutylicum ATCC 824, there is a spontaneous large-scale autolysis phenomenon with significant decrease of cell density immediately after exponential phase. To unravel the role of autolysis, an autolysin-coding gene, CA_C0554, was disrupted by using ClosTron system to obtain the mutant C. acetobutylicum lyc::int(72. The lower final cell density and faster cell density decrease rate of C. acetobutylicum ATCC 824 than those of C. acetobutylicum lyc::int(72 indicates that CA_C0554 was an important but not the sole autolysin-coding gene responding for the large-scale autolysis. Similar glucose utilization and solvents production but obvious lower cell density of C. acetobutylicum ATCC 824 comparing to C. acetobutylicum lyc::int(72 suggests that lysed C. acetobutylicum ATCC 824 cells were metabolic inactive. On the contrary, the spore density of C. acetobutylicum ATCC 824 is 26.1% higher than that of C. acetobutylicum lyc::int(72 in the final culture broth of batch fermentation. We speculated that spontaneous autolysis of metabolic-inactive cells provided nutrients for the sporulating cells. The present study suggests that one important biological role of spontaneous large-scale autolysis in C. acetobutylicum ATCC 824 batch fermentation is contributing to generation of more spores during sporulation.

  4. Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses.

    Science.gov (United States)

    Liu, Bo; Madduri, Ravi K; Sotomayor, Borja; Chard, Kyle; Lacinski, Lukasz; Dave, Utpal J; Li, Jianqiang; Liu, Chunchen; Foster, Ian T

    2014-06-01

    Due to the upcoming data deluge of genome data, the need for storing and processing large-scale genome data, easy access to biomedical analyses tools, efficient data sharing and retrieval has presented significant challenges. The variability in data volume results in variable computing and storage requirements, therefore biomedical researchers are pursuing more reliable, dynamic and convenient methods for conducting sequencing analyses. This paper proposes a Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses, which enables reliable and highly scalable execution of sequencing analyses workflows in a fully automated manner. Our platform extends the existing Galaxy workflow system by adding data management capabilities for transferring large quantities of data efficiently and reliably (via Globus Transfer), domain-specific analyses tools preconfigured for immediate use by researchers (via user-specific tools integration), automatic deployment on Cloud for on-demand resource allocation and pay-as-you-go pricing (via Globus Provision), a Cloud provisioning tool for auto-scaling (via HTCondor scheduler), and the support for validating the correctness of workflows (via semantic verification tools). Two bioinformatics workflow use cases as well as performance evaluation are presented to validate the feasibility of the proposed approach.

  5. Unscheduled load flow effect due to large variation in the distributed generation in a subtransmission network

    Science.gov (United States)

    Islam, Mujahidul

    A sustainable energy delivery infrastructure implies the safe and reliable accommodation of large scale penetration of renewable sources in the power grid. In this dissertation it is assumed there will be no significant change in the power transmission and distribution structure currently in place; except in the operating strategy and regulatory policy. That is to say, with the same old structure, the path towards unveiling a high penetration of switching power converters in the power system will be challenging. Some of the dimensions of this challenge are power quality degradation, frequent false trips due to power system imbalance, and losses due to a large neutral current. The ultimate result is the reduced life of many power distribution components - transformers, switches and sophisticated loads. Numerous ancillary services are being developed and offered by the utility operators to mitigate these problems. These services will likely raise the system's operational cost, not only from the utility operators' end, but also reflected on the Independent System Operators and by the Regional Transmission Operators (RTO) due to an unforeseen backlash of frequent variation in the load-side generation or distributed generation. The North American transmission grid is an interconnected system similar to a large electrical circuit. This circuit was not planned but designed over 100 years. The natural laws of physics govern the power flow among loads and generators except where control mechanisms are installed. The control mechanism has not matured enough to withstand the high penetration of variable generators at uncontrolled distribution ends. Unlike a radial distribution system, mesh or loop networks can alleviate complex channels for real and reactive power flow. Significant variation in real power injection and absorption on the distribution side can emerge as a bias signal on the routing reactive power in some physical links or channels that are not distinguishable

  6. On the generation and evolution of numerically simulated large-amplitude internal gravity wave packets

    Science.gov (United States)

    Abdilghanie, Ammar M.; Diamessis, Peter J.

    2012-01-01

    Numerical simulations of internal gravity wave (IGW) dynamics typically rely on wave velocity and density fields which are either generated through forcing terms in the governing equations or are explicitly introduced as initial conditions. Both approaches are based on the associated solution to the inviscid linear internal wave equations and, thus, assume weak-amplitude, space-filling waves. Using spectral multidomain-based numerical simulations of the two-dimensional Navier-Stokes equations and focusing on the forcing-driven approach, this study examines the generation and subsequent evolution of large-amplitude IGW packets which are strongly localized in the vertical in a linearly stratified fluid. When the vertical envelope of the forcing terms varies relatively rapid when compared to the vertical wavelength, the associated large vertical gradients in the Reynolds stress field drive a nonpropagating negative horizontal mean flow component in the source region. The highly nonlinear interaction of this mean current with the propagating IGW packet leads to amplification of the wave, a significant distortion of its rear flank, and a substantial decay of its amplitude. Scaling arguments show that the mean flow is enhanced with a stronger degree of localization of the forcing, larger degree of hydrostaticity, and increasing wave packet steepness. Horizontal localization results in a pronounced reduction in mean flow strength mainly on account of the reduced vertical gradient of the wave Reynolds stress. Finally, two techniques are proposed toward the efficient containment of the mean flow at minimal computational cost. The findings of this study are of particular value in overcoming challenges in the design of robust computational process studies of IGW packet (or continuously forced wave train) interactions with a sloping boundary, critical layer, or caustic, where large wave amplitudes are required for any instabilities to develop. In addition, the detailed

  7. Next-Generation Microshutter Arrays for Large-Format Imaging and Spectroscopy

    Science.gov (United States)

    Moseley, Samuel; Kutyrev, Alexander; Brown, Ari; Li, Mary

    2012-01-01

    A next-generation microshutter array, LArge Microshutter Array (LAMA), was developed as a multi-object field selector. LAMA consists of small-scaled microshutter arrays that can be combined to form large-scale microshutter array mosaics. Microshutter actuation is accomplished via electrostatic attraction between the shutter and a counter electrode, and 2D addressing can be accomplished by applying an electrostatic potential between a row of shutters and a column, orthogonal to the row, of counter electrodes. Microelectromechanical system (MEMS) technology is used to fabricate the microshutter arrays. The main feature of the microshutter device is to use a set of standard surface micromachining processes for device fabrication. Electrostatic actuation is used to eliminate the need for macromechanical magnet actuating components. A simplified electrostatic actuation with no macro components (e.g. moving magnets) required for actuation and latching of the shutters will make the microshutter arrays robust and less prone to mechanical failure. Smaller-size individual arrays will help to increase the yield and thus reduce the cost and improve robustness of the fabrication process. Reducing the size of the individual shutter array to about one square inch and building the large-scale mosaics by tiling these smaller-size arrays would further help to reduce the cost of the device due to the higher yield of smaller devices. The LAMA development is based on prior experience acquired while developing microshutter arrays for the James Webb Space Telescope (JWST), but it will have different features. The LAMA modular design permits large-format mosaicking to cover a field of view at least 50 times larger than JWST MSA. The LAMA electrostatic, instead of magnetic, actuation enables operation cycles at least 100 times faster and a mass significantly smaller compared to JWST MSA. Also, standard surface micromachining technology will simplify the fabrication process, increasing

  8. THE APPLICATION OF STATISTICAL PARAMETERS OF PHASE RESOLVED PD DISTRIBUTION TO AGING EXTENT ASSESSMENT OF LARGE GENERATOR INSULATION

    Institute of Scientific and Technical Information of China (English)

    谢恒堃; 乐波; 孙翔; 宋建成

    2003-01-01

    Objective To investigate the characteristic parameters employed to describe the aging extent of stator insulation of large generator and study the aging laws. Methods Multi-stress aging tests of model generator stator bar specimens were performed and PD measurements were conducted using digital PD detector with frequency range from 40*!kHz to 400*!kHz at different aging stage. Results From the test results of model specimens it was found that the skewness of phase resolved PD distribution might be taken as the characterization parameters for aging extent assessment of generator insulation. Furthermore, the measurement results of actual generator stator bars showed that the method based on statistical parameters of PD distributions are prospective for aging extent assessment and residual lifetime estimation of large generator insulation. Conclusion Statistical parameters of phase resolved PD distribution was proposed for aging extent assessment of large generator insulation.

  9. Hybrid column generation and large neighborhood search for the dial-a-ride problem

    Science.gov (United States)

    Parragh, Sophie N.; Schmid, Verena

    2013-01-01

    Demographic change towards an ever aging population entails an increasing demand for specialized transportation systems to complement the traditional public means of transportation. Typically, users place transportation requests, specifying a pickup and a drop off location and a fleet of minibuses or taxis is used to serve these requests. The underlying optimization problem can be modeled as a dial-a-ride problem. In the dial-a-ride problem considered in this paper, total routing costs are minimized while respecting time window, maximum user ride time, maximum route duration, and vehicle capacity restrictions. We propose a hybrid column generation and large neighborhood search algorithm and compare different hybridization strategies on a set of benchmark instances from the literature. PMID:23471127

  10. Hybrid column generation and large neighborhood search for the dial-a-ride problem.

    Science.gov (United States)

    Parragh, Sophie N; Schmid, Verena

    2013-01-01

    Demographic change towards an ever aging population entails an increasing demand for specialized transportation systems to complement the traditional public means of transportation. Typically, users place transportation requests, specifying a pickup and a drop off location and a fleet of minibuses or taxis is used to serve these requests. The underlying optimization problem can be modeled as a dial-a-ride problem. In the dial-a-ride problem considered in this paper, total routing costs are minimized while respecting time window, maximum user ride time, maximum route duration, and vehicle capacity restrictions. We propose a hybrid column generation and large neighborhood search algorithm and compare different hybridization strategies on a set of benchmark instances from the literature.

  11. Solving Large Scale Nonlinear Eigenvalue Problem in Next-Generation Accelerator Design

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Ben-Shan; Bai, Zhaojun; /UC, Davis; Lee, Lie-Quan; Ko, Kwok; /SLAC

    2006-09-28

    A number of numerical methods, including inverse iteration, method of successive linear problem and nonlinear Arnoldi algorithm, are studied in this paper to solve a large scale nonlinear eigenvalue problem arising from finite element analysis of resonant frequencies and external Q{sub e} values of a waveguide loaded cavity in the next-generation accelerator design. They present a nonlinear Rayleigh-Ritz iterative projection algorithm, NRRIT in short and demonstrate that it is the most promising approach for a model scale cavity design. The NRRIT algorithm is an extension of the nonlinear Arnoldi algorithm due to Voss. Computational challenges of solving such a nonlinear eigenvalue problem for a full scale cavity design are outlined.

  12. EIRP Characterization of Electrically Large Wireless Equipment with Integrated Signal Generator in a Compact Environment

    Directory of Open Access Journals (Sweden)

    Soon-Soo Oh

    2015-01-01

    Full Text Available We describe a measurement technique to characterize the equivalent isotropically radiated power (EIRP of electrically large wireless equipment in a compact environment. A modified phase-measurement method was proposed and, thus, the separation of the signal generator and radiating element was not required during the measurement. A Fresnel-to-far-field transformation was used for the fast measurement time in a compact anechoic chamber. An experimental verification of the method was carried out in a compact anechoic chamber, where the source-detector separation was approximately 1/5 of the far-field distance. The measured magnitude and phase pattern exhibited only a small error. The EIRP obtained using a Fresnel-to-far-field transformation was compared with a reference value, and the error was within 0.5 dB.

  13. Collision Avoidance in Next-generation Fiber Positioner Robotic System for Large Survey Spectrograph

    CERN Document Server

    Makarem, Laleh; Gillet, Denis; Bleuler, Hannes; Bouri, Mohamed; Jenni, Laurent; Prada, Francisco; Sanchez, Justo

    2013-01-01

    Some of the next generation massive spectroscopic survey projects, such as DESI and PFS, plan to use thousands of fiber positioner robots packed at a focal plane to quickly move in parallel the fiber-ends from the previous to the next target points. The most direct trajectories are prone to collision that could damage the robots and impact the survey operation. We thus present here a motion planning method based on a novel decentralized navigation function for collision-free coordination of fiber positioners. The navigation function takes into account the configuration of positioners as well as the actuator constraints. We provide details for the proof of convergence and collision avoidance. Decentralization results in linear complexity for the motion planning as well as dependency of motion duration with respect to the number of positioners. Therefore the coordination method is scalable for large-scale spectrograph robots. The short in-motion duration of positioner robots (~2.5 seconds using typical actuator...

  14. Large eddy simulations of flow instabilities in a stirred tank generate by a Rushton turbine

    DEFF Research Database (Denmark)

    Fan, Jianhua; Wang, Yundong; Fei, Weiyang

    2007-01-01

    The aim of this paper is to investigate the flow instabilities in a baffled, stirred tank generated by a single Rushton turbine by means of large eddy simulation (LES) and simulation using the k-ε turbulent model. A sliding mesh method was used for the coupling between the rotating...... that CFD simulations using k-ε model and LES approach agreed well with the DPIV measurement. Fluctuations of the radial and axial velocity were well predicted at different frequencies by the LES simulation. Velocity fluctuations of high frequencies were observed in the impeller region, while low...... computational time and computer memories. The results of the present work give better understanding to the mixing mechanisms in the mechanically agitated tank....

  15. Dynamics of self-generated, large amplitude magnetic fields following high-intensity laser matter interaction

    CERN Document Server

    Sarri, G; Cecchetti, C A; Kar, S; Liseykina, T V; Yang, X H; Dieckmann, M E; Fuchs, J; Galimberti, M; Gizzi, L A; Jung, R; Kourakis, I; Osterholz, J; Pegoraro, F; Robinson, A P L; Romagnani, L; Willi, O; Borghesi, M

    2012-01-01

    The dynamics of magnetic fields with amplitude of several tens of Megagauss, generated at both sides of a solid target irradiated with a high intensity (? 1019W/cm2) picosecond laser pulse, has been spatially and temporally resolved using a proton imaging technique. The amplitude of the magnetic fields is sufficiently large to have a constraining effect on the radial expansion of the plasma sheath at the target surfaces. These results, supported by numerical simulations and simple analytical modeling, may have implications for ion acceleration driven by the plasma sheath at the rear side of the target as well as for the laboratory study of self-collimated high-energy plasma jets.

  16. Next Generation Very Large Array Memo No. 6, Science Working Group 1: The Cradle of Life

    CERN Document Server

    Isella, Andrea; Moullet, Arielle; Galván-Madrid, Roberto; Johnstone, Doug; Ricci, Luca; Tobin, John; Testi, Leonardo; Beltran, Maite; Lazio, Joseph; Siemion, Andrew; Liu, Hauyu Baobab; Du, Fujun; Öberg, Karin I; Bergin, Ted; Caselli, Paola; Bourke, Tyler; Carilli, Chris; Perez, Laura; Butler, Bryan; de Pater, Imke; Qi, Chunhua; Hofstadter, Mark; Moreno, Raphael; Alexander, David; Williams, Jonathan; Goldsmith, Paul; Wyatt, Mark; Loinard, Laurent; Di Francesco, James; Wilner, David; Schilke, Peter; Ginsburg, Adam; Sánchez-Monge, Álvaro; Zhang, Qizhou; Beuther, Henrik

    2015-01-01

    This paper discusses compelling science cases for a future long-baseline interferometer operating at millimeter and centimeter wavelengths, like the proposed Next Generation Vary Large Array (ngVLA). We report on the activities of the Cradle of Life science working group, which focused on the formation of low- and high-mass stars, the formation of planets and evolution of protoplanetary disks, the physical and compositional study of Solar System bodies, and the possible detection of radio signals from extraterrestrial civilizations. We propose 19 scientific projects based on the current specification of the ngVLA. Five of them are highlighted as possible Key Science Projects: (1) Resolving the density structure and dynamics of the youngest HII regions and high-mass protostellar jets, (2) Unveiling binary/multiple protostars at higher resolution, (3) Mapping planet formation regions in nearby disks on scales down to 1 AU, (4) Studying the formation of complex molecules, and (5) Deep atmospheric mapping of gian...

  17. Optimum siting and sizing of a large distributed generator in a mesh connected system

    Energy Technology Data Exchange (ETDEWEB)

    Elnashar, Mohab M.; El Shatshat, Ramadan; Salama, Magdy M.A. [Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, Ontario (Canada)

    2010-06-15

    This paper proposes a new approach to optimally determine the appropriate size and location of the distributed generator (DG) in a large mesh connected system. This paper presents a visual optimization approach in which the planner plays an important role in determining the optimal siting and sizing of the DG through the choice of the appropriate weight factors of the parameters included in the optimization technique according to the system deficiencies. Losses, voltage profile and short circuit level are used in the algorithm to determine the optimum sizes and locations of the DG. The short circuit level parameter is introduced to represent the protective device requirements in the selection of the size and location of the DG. The proposed technique has been tested on the IEEE 24 - bus mesh connected test system. The obtained results showed clearly that the optimal size and location can be simply determined through the proposed approach. (author)

  18. Nonlinear ionospheric responses to large-amplitude infrasonic-acoustic waves generated by undersea earthquakes

    Science.gov (United States)

    Zettergren, M. D.; Snively, J. B.; Komjathy, A.; Verkhoglyadova, O. P.

    2017-02-01

    Numerical models of ionospheric coupling with the neutral atmosphere are used to investigate perturbations of plasma density, vertically integrated total electron content (TEC), neutral velocity, and neutral temperature associated with large-amplitude acoustic waves generated by the initial ocean surface displacements from strong undersea earthquakes. A simplified source model for the 2011 Tohoku earthquake is constructed from estimates of initial ocean surface responses to approximate the vertical motions over realistic spatial and temporal scales. Resulting TEC perturbations from modeling case studies appear consistent with observational data, reproducing pronounced TEC depletions which are shown to be a consequence of the impacts of nonlinear, dissipating acoustic waves. Thermospheric acoustic compressional velocities are ˜±250-300 m/s, superposed with downward flows of similar amplitudes, and temperature perturbations are ˜300 K, while the dominant wave periodicity in the thermosphere is ˜3-4 min. Results capture acoustic wave processes including reflection, onset of resonance, and nonlinear steepening and dissipation—ultimately leading to the formation of ionospheric TEC depletions "holes"—that are consistent with reported observations. Three additional simulations illustrate the dependence of atmospheric acoustic wave and subsequent ionospheric responses on the surface displacement amplitude, which is varied from the Tohoku case study by factors of 1/100, 1/10, and 2. Collectively, results suggest that TEC depletions may only accompany very-large amplitude thermospheric acoustic waves necessary to induce a nonlinear response, here with saturated compressional velocities ˜200-250 m/s generated by sea surface displacements exceeding ˜1 m occurring over a 3 min time period.

  19. Large scale generation of micro-droplet array by vapor condensation on mesh screen piece

    Science.gov (United States)

    Xie, Jian; Xu, Jinliang; He, Xiaotian; Liu, Qi

    2017-01-01

    We developed a novel micro-droplet array system, which is based on the distinct three dimensional mesh screen structure and sintering and oxidation induced thermal-fluid performance. Mesh screen was sintered on a copper substrate by bonding the two components. Non-uniform residue stress is generated along weft wires, with larger stress on weft wire top location than elsewhere. Oxidation of the sintered package forms micro pits with few nanograsses on weft wire top location, due to the stress corrosion mechanism. Nanograsses grow elsewhere to show hydrophobic behavior. Thus, surface-energy-gradient weft wires are formed. Cooling the structure in a wet air environment nucleates water droplets on weft wire top location, which is more “hydrophilic” than elsewhere. Droplet size is well controlled by substrate temperature, air humidity and cooling time. Because warp wires do not contact copper substrate and there is a larger conductive thermal resistance between warp wire and weft wire, warp wires contribute less to condensation but function as supporting structure. The surface energy analysis of drops along weft wires explains why droplet array can be generated on the mesh screen piece. Because the commercial material is used, the droplet system is cost effective and can be used for large scale utilization.

  20. Large amplitude, leaky, island-generated, internal waves around Palau, Micronesia

    Science.gov (United States)

    Wolanski, E.; Colin, P.; Naithani, J.; Deleersnijder, E.; Golbuu, Y.

    2004-08-01

    Three years of temperature data along two transects extending to 90 m depth, at Palau, Micronesia, show twice-a-day thermocline vertical displacements of commonly 50-100 m, and on one occasion 270 m. The internal wave occurred at a number of frequencies. There were a number of spectral peaks at diurnal and semi-diurnal frequencies, as well as intermediate and sub-inertial frequencies, less so at the inertial frequency. At Palau the waves generally did not travel around the island because there was no coherence between internal waves on either side of the island. The internal waves at a site 30 km offshore were out-of-phase with those on the island slopes, suggesting that the waves were generated on the island slope and then radiated away. Palau Island was thus a source of internal wave energy for the surrounding ocean. A numerical model suggests that the tidal and low-frequency currents flowing around the island form internal waves with maximum wave amplitude on the island slope and that these waves radiate away from the island. The model also suggests that the headland at the southern tip of Palau prevents the internal waves to rotate around the island. The large temperature fluctuations (commonly daily fluctuations ≈10 °C, peaking at 20 °C) appear responsible for generating a thermal stress responsible for a biologically depauperate biological community on the island slopes at depths between 60 and 120 m depth.

  1. A Simulink Library of cryogenic components to automatically generate control schemes for large Cryorefrigerators

    Science.gov (United States)

    Bonne, François; Alamir, Mazen; Hoa, Christine; Bonnay, Patrick; Bon-Mardion, Michel; Monteiro, Lionel

    2015-12-01

    In this article, we present a new Simulink library of cryogenics components (such as valve, phase separator, mixer, heat exchanger...) to assemble to generate model-based control schemes. Every component is described by its algebraic or differential equation and can be assembled with others to build the dynamical model of a complete refrigerator or the model of a subpart of it. The obtained model can be used to automatically design advanced model based control scheme. It also can be used to design a model based PI controller. Advanced control schemes aim to replace classical user experience designed approaches usually based on many independent PI controllers. This is particularly useful in the case where cryoplants are submitted to large pulsed thermal loads, expected to take place in future fusion reactors such as those expected in the cryogenic cooling systems of the International Thermonuclear Experimental Reactor (ITER) or the Japan Torus-60 Super Advanced Fusion Experiment (JT- 60SA). The paper gives the example of the generation of the dynamical model of the 400W@1.8K refrigerator and shows how to build a Constrained Model Predictive Control for it. Based on the scheme, experimental results will be given. This work is being supported by the French national research agency (ANR) through the ANR-13-SEED-0005 CRYOGREEN program.

  2. Torque characteristics in a large permanent magnet synchronous generator with stator radial ventilating air ducts

    Institute of Scientific and Technical Information of China (English)

    He HAO; Wei-zhong FEI; Dong-min MIAO; Meng-jia JIN; Jian-xin SHEN

    2016-01-01

    In this study, we investigated the torque characteristics of large low-speed direct-drive permanent magnet synchronous generators with stator radial ventilating air ducts for offshore wind power applications. Magnet shape optimization was used fi rst to improve the torque characteristics using two-dimensional fi nite element analysis (FEA) in a permanent magnet synchronous generator with a common stator. The rotor step skewing technique was then employed to suppress the impacts of mechanical tolerances and defects, which further improved the torque quality of the machine. Comprehensive three-dimensional FEA was used to evaluate accurately the overall effects of stator radial ventilating air ducts and rotor step skewing on torque features. The infl uences of the radial ventilating ducts in the stator on torque characteristics, such as torque pulsation and average torque in the machine with and without rotor step skewing techniques, were comprehensively investigated using three-dimensional FEA. The results showed that stator radial ventilating air ducts could not only reduce the average torque but also increase the torque ripple in the machine. Furthermore, the torque ripple of the machine under certain load conditions may even be increased by rotor step skewing despite a reduction in cogging torque.

  3. Rucio - The next generation of large scale distributed system for ATLAS Data Management

    CERN Document Server

    Garonne, V; The ATLAS collaboration; Beermann, T; Goossens, L; Lassnig, M; Nairz, A; Stewart, GA; Vigne, V; Serfon, C

    2013-01-01

    Rucio is the next-generation Distributed Data Management(DDM) system benefiting from recent advances in cloud and "Big Data" computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 140 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will address these issues by relying on a conceptual data model and new technology to ensure system scalability, address new user requirements and employ new automation framework to reduce operational overheads. We present the key concepts of Rucio, including its data organization/representation and a model of how ATLAS central group and user activities will be managed. The Rucio design, and the technology it employs, is described...

  4. Rucio - The next generation of large scale distributed system for ATLAS Data Management

    CERN Document Server

    Garonne, V; The ATLAS collaboration; Beermann, T; Goossens, L; Lassnig, M; Nairz, A; Stewart, GA; Vigne, V; Serfon, C

    2014-01-01

    Rucio is the next-generation Distributed Data Management(DDM) system benefiting from recent advances in cloud and ”Big Data” computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 140 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will address these issues by relying on a conceptual data model and new technology to ensure system scalability, address new user requirements and employ new automation framework to reduce operational overheads. We present the key concepts of Rucio, including its data organization/representation and a model of how ATLAS central group and user activities will be managed. The Rucio design, and the technology it employs, is descr...

  5. Rucio - The next generation of large scale distributed system for ATLAS Data Management

    Science.gov (United States)

    Garonne, V.; Vigne, R.; Stewart, G.; Barisits, M.; eermann, T. B.; Lassnig, M.; Serfon, C.; Goossens, L.; Nairz, A.; Atlas Collaboration

    2014-06-01

    Rucio is the next-generation Distributed Data Management (DDM) system benefiting from recent advances in cloud and "Big Data" computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 140 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will deal with these issues by relying on a conceptual data model and new technology to ensure system scalability, address new user requirements and employ new automation framework to reduce operational overheads. We present the key concepts of Rucio, including its data organization/representation and a model of how to manage central group and user activities. The Rucio design, and the technology it employs, is described, specifically looking at its RESTful architecture and the various software components it uses. We show also the performance of the system.

  6. Time Domain Science and Fundamental Physics with the Next-generation Very Large Array

    Science.gov (United States)

    Demorest, Paul; Bower, Geoffrey C.; ngVLA Time Domain/Physics Science Working Group

    2017-01-01

    The Next-generation Very Large Array (ngVLA) is a design concept for a future large-area radio telescope under development by the NRAO and interested members of the scientific community. The approximate ngVLA specifications call for a frequency range of ~1--116 GHz, ten times the effective collecting area and moderately increased field of view versus the current VLA, and an array configuration consisting of a dense (~km-scale) array core with some baselines extending out to hundreds of km. This instrument will enable new discoveries in many diverse areas of research relevant to modern astronomy; our group has explored the impact the ngVLA will have in time domain astronomy and fundamental physics.Here we present several key science topics considered as part of this work. These include: Searching for and timing radio pulsars at the galactic center -- the frequency coverage and sensitivity of the ngVLA will allow detection of highly-scattered pulsars near Sgr A*. Monitoring these sources will permit unprecedented tests of general relativity. Detecting and characterizing explosive transient sources -- electromagnetic observations of gravitational-wave sources provide complementary information to the GW signals themselves. Observations across the wide frequency range spanned by the ngVLA are critical for energy calorimetry of these events. Finally, with sufficient long-baseline coverage, novel astrometric approaches to cosmology become possible, by watching the expansion of the universe in real time through correlated proper motions of many extragalactic radio sources.

  7. Generative models of rich clubs in Hebbian neuronal networks and large-scale human brain networks.

    Science.gov (United States)

    Vértes, Petra E; Alexander-Bloch, Aaron; Bullmore, Edward T

    2014-10-05

    Rich clubs arise when nodes that are 'rich' in connections also form an elite, densely connected 'club'. In brain networks, rich clubs incur high physical connection costs but also appear to be especially valuable to brain function. However, little is known about the selection pressures that drive their formation. Here, we take two complementary approaches to this question: firstly we show, using generative modelling, that the emergence of rich clubs in large-scale human brain networks can be driven by an economic trade-off between connection costs and a second, competing topological term. Secondly we show, using simulated neural networks, that Hebbian learning rules also drive the emergence of rich clubs at the microscopic level, and that the prominence of these features increases with learning time. These results suggest that Hebbian learning may provide a neuronal mechanism for the selection of complex features such as rich clubs. The neural networks that we investigate are explicitly Hebbian, and we argue that the topological term in our model of large-scale brain connectivity may represent an analogous connection rule. This putative link between learning and rich clubs is also consistent with predictions that integrative aspects of brain network organization are especially important for adaptive behaviour.

  8. Next Generation Very Large Array Memo No. 5: Science Working Groups -- Project Overview

    CERN Document Server

    Carilli, C L; Ott, J; Beasley, A; Isella, A; Murphy, E; Leroy, A; Casey, C; Moullet, A; Lacy, M; Hodge, J; Bower, G; Demorest, P; Hull, C; Hughes, M; di Francesco, J; Narayanan, D; Kent, B; Clark, B; Butler, B

    2015-01-01

    We summarize the design, capabilities, and some of the priority science goals of a next generation Very Large Array (ngVLA). The ngVLA is an interferometric array with 10x larger effective collecting area and 10x higher spatial resolution than the current VLA and the Atacama Large Millimeter Array (ALMA), optimized for operation in the wavelength range 0.3cm to 3cm. The ngVLA opens a new window on the Universe through ultra-sensitive imaging of thermal line and continuum emission down to milliarcecond resolution, as well as unprecedented broad band continuum polarimetric imaging of non-thermal processes. The continuum resolution will reach 9mas at 1cm, with a brightness temperature sensitivity of 6K in 1 hour. For spectral lines, the array at 1" resolution will reach 0.3K surface brightness sensitivity at 1cm and 10 km/s spectral resolution in 1 hour. These capabilities are the only means with which to answer a broad range of critical scientific questions in modern astronomy, including direct imaging of plane...

  9. Antenna Electronics Concept for the Next-Generation Very Large Array

    Science.gov (United States)

    Beasley, Anthony J.; Jackson, Jim; Selina, Robert

    2017-01-01

    The National Radio Astronomy Observatory (NRAO), in collaboration with its international partners, completed two major projects over the past decade: the sensitivity upgrade for the Karl Jansky Very Large Array (VLA) and the construction of the Atacama Large Millimeter/Sub-Millimeter Array (ALMA). The NRAO is now considering the scientific potential and technical feasibility of a next-generation VLA (ngVLA) with an emphasis on thermal imaging at milli-arcsecond resolution. The preliminary goals for the ngVLA are to increase both the system sensitivity and angular resolution of the VLA tenfold and to cover a frequency range of 1.2-116 GHz.A number of key technical challenges have been identified for the project. These include cost-effective antenna manufacturing (in the hundreds), suitable wide-band feed and receiver designs, broad-band data transmission, and large-N correlators. Minimizing the overall operations cost is also a fundamental design requirement.The designs of the antenna electronics, reference distribution system, and data transmission system are anticipated to be major construction and operations cost drivers for the facility. The electronics must achieve a high level of performance, while maintaining low operation and maintenance costs and a high level of reliability. Additionally, due to the uncertainty in the feasibility of wideband receivers, advancements in digitizer technology, and budget constraints, the hardware system architecture should be scalable to the number of receiver bands and the speed and resolution of available digitizers.Here, we present the projected performance requirements of the ngVLA, a proposed block diagram for the instrument’s electronics systems, parameter tradeoffs within the system specifications, and areas of technical risk where technical advances may be required for successful production and installation.

  10. Generating descriptive visual words and visual phrases for large-scale image applications.

    Science.gov (United States)

    Zhang, Shiliang; Tian, Qi; Hua, Gang; Huang, Qingming; Gao, Wen

    2011-09-01

    Bag-of-visual Words (BoWs) representation has been applied for various problems in the fields of multimedia and computer vision. The basic idea is to represent images as visual documents composed of repeatable and distinctive visual elements, which are comparable to the text words. Notwithstanding its great success and wide adoption, visual vocabulary created from single-image local descriptors is often shown to be not as effective as desired. In this paper, descriptive visual words (DVWs) and descriptive visual phrases (DVPs) are proposed as the visual correspondences to text words and phrases, where visual phrases refer to the frequently co-occurring visual word pairs. Since images are the carriers of visual objects and scenes, a descriptive visual element set can be composed by the visual words and their combinations which are effective in representing certain visual objects or scenes. Based on this idea, a general framework is proposed for generating DVWs and DVPs for image applications. In a large-scale image database containing 1506 object and scene categories, the visual words and visual word pairs descriptive to certain objects or scenes are identified and collected as the DVWs and DVPs. Experiments show that the DVWs and DVPs are informative and descriptive and, thus, are more comparable with the text words than the classic visual words. We apply the identified DVWs and DVPs in several applications including large-scale near-duplicated image retrieval, image search re-ranking, and object recognition. The combination of DVW and DVP performs better than the state of the art in large-scale near-duplicated image retrieval in terms of accuracy, efficiency and memory consumption. The proposed image search re-ranking algorithm: DWPRank outperforms the state-of-the-art algorithm by 12.4% in mean average precision and about 11 times faster in efficiency.

  11. The Combination of Tissue Dissection and External Volume Expansion Generates Large Volumes of Adipose Tissue.

    Science.gov (United States)

    He, Yunfan; Dong, Ziqing; Xie, Gan; Zhou, Tao; Lu, Feng

    2017-04-01

    Noninvasive external volume expansion device has been applied to stimulate nonsurgical breast enlargement in clinical settings. Although previous results demonstrate the capacity of external volume expansion to increase the number of adipocytes, this strategy alone is insufficient to reconstruct soft-tissue defects or increase breast mass. The authors combined a minimally invasive tissue dissection method with external volume expansion to generate large volumes of adipose tissue. In vitro, various densities of adipose-derived stem cells were prepared to evaluate relations between cell contacts and cell proliferation. In vivo, dorsal adipose tissue of rabbits was thoroughly dissected and the external volume expansion device was applied to maintain the released state. External volume expansion without tissue dissection served as the control. In the dissection group, the generated adipose tissue volume was much larger than that in the control group at all time points. A larger number of proliferating cells appeared in the dissection samples than in the control samples at the early stage after tissue dissection. At low cell density, adipose-derived stem cells displayed an increasing proliferation rate compared to high cell density. Protein expression analysis revealed that cell proliferation was mediated by a similar mechanism both in vivo and in vitro, involving the release of cell contact inhibition and Hippo/Yes-associated protein pathway activation. Adipose tissue dissection releases cell-to-cell contacts and induces adipose-derived stem cell proliferation. Preexpanded adipose-derived stem cells undergo adipogenesis under the adipogenic environment created by external volume expansion, leading to better adipose regeneration compared with the control.

  12. Kinetic Alfvén Wave Generation by Large-scale Phase Mixing

    Science.gov (United States)

    Vásconez, C. L.; Pucci, F.; Valentini, F.; Servidio, S.; Matthaeus, W. H.; Malara, F.

    2015-12-01

    One view of the solar wind turbulence is that the observed highly anisotropic fluctuations at spatial scales near the proton inertial length dp may be considered as kinetic Alfvén waves (KAWs). In the present paper, we show how phase mixing of large-scale parallel-propagating Alfvén waves is an efficient mechanism for the production of KAWs at wavelengths close to dp and at a large propagation angle with respect to the magnetic field. Magnetohydrodynamic (MHD), Hall magnetohydrodynamic (HMHD), and hybrid Vlasov-Maxwell (HVM) simulations modeling the propagation of Alfvén waves in inhomogeneous plasmas are performed. In the linear regime, the role of dispersive effects is singled out by comparing MHD and HMHD results. Fluctuations produced by phase mixing are identified as KAWs through a comparison of polarization of magnetic fluctuations and wave-group velocity with analytical linear predictions. In the nonlinear regime, a comparison of HMHD and HVM simulations allows us to point out the role of kinetic effects in shaping the proton-distribution function. We observe the generation of temperature anisotropy with respect to the local magnetic field and the production of field-aligned beams. The regions where the proton-distribution function highly departs from thermal equilibrium are located inside the shear layers, where the KAWs are excited, this suggesting that the distortions of the proton distribution are driven by a resonant interaction of protons with KAW fluctuations. Our results are relevant in configurations where magnetic-field inhomogeneities are present, as, for example, in the solar corona, where the presence of Alfvén waves has been ascertained.

  13. High-Efficiency, Multijunction Solar Cells for Large-Scale Solar Electricity Generation

    Science.gov (United States)

    Kurtz, Sarah

    2006-03-01

    A solar cell with an infinite number of materials (matched to the solar spectrum) has a theoretical efficiency limit of 68%. If sunlight is concentrated, this limit increases to about 87%. These theoretical limits are calculated using basic physics and are independent of the details of the materials. In practice, the challenge of achieving high efficiency depends on identifying materials that can effectively use the solar spectrum. Impressive progress has been made with the current efficiency record being 39%. Today's solar market is also showing impressive progress, but is still hindered by high prices. One strategy for reducing cost is to use lenses or mirrors to focus the light on small solar cells. In this case, the system cost is dominated by the cost of the relatively inexpensive optics. The value of the optics increases with the efficiency of the solar cell. Thus, a concentrator system made with 35%- 40%-efficient solar cells is expected to deliver 50% more power at a similar cost when compare with a system using 25%-efficient cells. Today's markets are showing an opportunity for large concentrator systems that didn't exist 5-10 years ago. Efficiencies may soon pass 40% and ultimately may reach 50%, providing a pathway to improved performance and decreased cost. Many companies are currently investigating this technology for large-scale electricity generation. The presentation will cover the basic physics and more practical considerations to achieving high efficiency as well as describing the current status of the concentrator industry. This work has been authored by an employee of the Midwest Research Institute under Contract No. DE- AC36-99GO10337 with the U.S. Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, worldwide license to publish or reproduce the published form of this work, or allow

  14. KINETIC ALFVÉN WAVE GENERATION BY LARGE-SCALE PHASE MIXING

    Energy Technology Data Exchange (ETDEWEB)

    Vásconez, C. L.; Pucci, F.; Valentini, F.; Servidio, S.; Malara, F. [Dipartimento di Fisica, Università della Calabria, I-87036, Rende (CS) (Italy); Matthaeus, W. H. [Department of Physics and Astronomy, University of Delaware, DE 19716 (United States)

    2015-12-10

    One view of the solar wind turbulence is that the observed highly anisotropic fluctuations at spatial scales near the proton inertial length d{sub p} may be considered as kinetic Alfvén waves (KAWs). In the present paper, we show how phase mixing of large-scale parallel-propagating Alfvén waves is an efficient mechanism for the production of KAWs at wavelengths close to d{sub p} and at a large propagation angle with respect to the magnetic field. Magnetohydrodynamic (MHD), Hall magnetohydrodynamic (HMHD), and hybrid Vlasov–Maxwell (HVM) simulations modeling the propagation of Alfvén waves in inhomogeneous plasmas are performed. In the linear regime, the role of dispersive effects is singled out by comparing MHD and HMHD results. Fluctuations produced by phase mixing are identified as KAWs through a comparison of polarization of magnetic fluctuations and wave-group velocity with analytical linear predictions. In the nonlinear regime, a comparison of HMHD and HVM simulations allows us to point out the role of kinetic effects in shaping the proton-distribution function. We observe the generation of temperature anisotropy with respect to the local magnetic field and the production of field-aligned beams. The regions where the proton-distribution function highly departs from thermal equilibrium are located inside the shear layers, where the KAWs are excited, this suggesting that the distortions of the proton distribution are driven by a resonant interaction of protons with KAW fluctuations. Our results are relevant in configurations where magnetic-field inhomogeneities are present, as, for example, in the solar corona, where the presence of Alfvén waves has been ascertained.

  15. BLAST-TNG: A Next Generation Balloon-borne Large Aperture Submillimeter Polarimeter

    Science.gov (United States)

    Fissel, Laura M.; Ade, Peter; Angilè, Francesco E.; Campbell Ashton, Peter; Austermann, Jason Edward; Billings, Tashalee; Che, George; Cho, Hsiao-Mei; Cunningham, Maria R.; Davis, Kristina; Devlin, Mark J.; Dicker, Simon; Dober, Bradley; Fukui, Yasuo; Galitzki, Nicholas; gao, jiansong; Gordon, Sam; Groppi, Christopher E.; Hillbrand, Seth; Hilton, Gene; Hubmayr, Hannes; Irwin, Kent; Jones, Paul; Klein, Jeffrey; li, dale; Li, Zhi-Yun; lourie, nathan; Lowe, Ian; Mani, Hamdi; Martin, Peter G.; Mauskopf, Philip; McKenney, Christopher; Nati, Federico; Novak, Giles; Pascale, Enzo; pisano, giampaolo; Pereira Santos, Fábio; Scott, Douglas; Sinclair, Adrian; Diego Diego Soler, Juan; tucker, carole; Underhill, Matthew; Vissers, Michael; Williams, Paul

    2017-01-01

    Measurements of polarized thermal dust emission can be used to map magnetic fields in the interstellar medium. Recently, BLASTPol, the Balloon-borne Large Aperture Submillimeter Telescope for Polarimetry, has published the most detailed map ever made of a giant molecular cloud forming high-mass stars. I will present an overview of The Next Generation BLAST polarimeter (BLAST-TNG), the successor telescope to BLASTPol, which maps linearly polarized dust emission at 250, 350 and 500 μm. BLAST-TNG utilizes a 2.5-meter carbon-fiber primary mirror that illuminates focal plane arrays containing over 3,000 microwave kinetic inductance detectors. This new polarimeter has an order of magnitude increase in mapping speed and resolution compared to BLASTPol and we expect to make over 500,000 measurements of magnetic field orientation per flight. BLAST-TNG will have the sensitivity to map entire molecular cloud complexes as well as regions of diffuse high Galactic latitude dust. It also has the resolution (FWHM = 25’’ at 250 μm) necessary to trace magnetic fields in prestellar cores and dense filaments. BLAST-TNG will thus provide a crucial link between the low resolution Planck all-sky maps and the detailed but narrow field of view polarimetry capabilities of ALMA. For our first Antarctic flight in December 2017 we are putting out a call for shared-risk proposals to fill 25% of the available science time. In addition, BLAST-TNG data will be publicly released within a year of the publication of our first look papers, leaving a large legacy data set for the study of the role played by magnetic fields in the star formation process and the properties of interstellar dust.

  16. Antenna Optics and Receiver Concept for the Next Generation Very Large Array

    Science.gov (United States)

    McKinnon, Mark M.; Srikanth, Sivasankaran; Grammer, Wes; Pospieszalski, Marian; Sturgis, Silver

    2017-01-01

    The Next Generation Very Large Array (ngVLA) is envisioned to be an interferometric array with 10 times the effective collecting area and 10 times higher spatial resolution than the current VLA, operating over a frequency range of 1.2-116 GHz. Achieving these goals will require about 300 antennas of nominally 18m diameter on baselines of 300km. Options for the optical configuration of the antennas and possible receiver configurations to cover the ngVLA frequency range are presented. The options for the antenna optics take into account performance, cost, receiver accessibility for maintenance purposes, and receiver distribution in the focal plane. Both on-axis and off-axis configurations are considered. The off-axis design has the advantages of higher gain, low near-in sidelobes, lower antenna temperature, and reduced standing waves. The main advantage of the on-axis configuration is its lower cost. The trade-off between subreflector opening angle and feed size is presented. The performance of different dual-offset reflector geometries is summarized. The ngVLA receivers will be cryogenically-cooled with cryostats integrating multiple receiver bands for reduced maintenance and operating costs. The total number of bands required depends on their fractional bandwidth: maximizing this reduces the band count and number of cryostats, but with a penalty in sensitivity. For the higher frequencies, waveguide-bandwidth receivers are proposed to cover 11-50 GHz and 70-116 GHz in four separate bands, possibly integrated into a single cryostat. Corrugated conical feeds will be used, providing good aperture efficiency and symmetric, uniform beam shape. For 1.2-11 GHz, waveguide-bandwidth receivers are not practical due to the large number of receiver/feed combinations needed to cover the ~9:1 frequency range. Also, the large size of the feeds and polarizers mandates individual cryostats for each band. A possible compromise is two 3:1-bandwidth receivers with smooth

  17. Applications of large-area nanopatterning to energy generation and storage devices

    Science.gov (United States)

    Mills, Eric N.

    This dissertation encompasses the creation and testing of nanostructured, electrochemically-active energy generation and storage devices, and development of the associated fabrication techniques. The fabricated devices include nanopatterned, plasmonically-active, TiO2+Au thin films for Photocatalytic Water Splitting (PCW), TiO2-based Dye-Sensitized Solar Cells (DSSCs) incorporating nanopatterned, plasmonically-active metallic front electrodes, and Si nanopillar anodes for Li-ion batteries. Techniques were also developed for encapsulation and removal of wet-etched Si nanowires from their mother substrates. TiO2 was the first material to be widely used for PCW. Its use is hampered by its large bandgap (~3.2eV), and poor recombination lifetimes. Au nanoparticles (NPs) have been previously used to improve recombination lifetimes in TiO2 by separating photogenerated carriers near the NP edges, and to increase photocurrents by injecting plasmonically-excited hot electrons into the TiO2 conduction band. Using nanostructured TiO 2+Au electrodes, we aim to increase the PCW efficiency of TiO2 -based electrodes. Dye-sensitized solar cells (DSSCs) employ visible-absorbing dyes anchored to a high-surface-area semiconducting scaffold. The front transparent conducting electrode (TCE) is typically ITO, a scarce and expensive material. We aim to increase the efficiency of thin-film DSSCs and eliminate the use of ITO by using a metallic subwavelength array (MESH) of nanoholes as the front TCE. Silicon holds promise as a high-capacity anode material for Li-ion batteries, as it can store ~10x the Li of graphite, the current leading anode material (3569 vs. 372 mAh/g). However, Si undergoes dramatic (>300%) volume expansion upon "lithiation", pulverizing any structure with non-nanoscopic dimensions (>250nm). We created large-area arrays of "nanopillars" with sub-100nm diameters, using roll-to-roll-compatible flexible-mold NIL on commercially-available metal substrates. Ordered

  18. Incremental N-mode SVD for large-scale multilinear generative models.

    Science.gov (United States)

    Lee, Minsik; Choi, Chong-Ho

    2014-10-01

    Tensor decomposition is frequently used in image processing and machine learning for its ability to express higher order characteristics of data. Among tensor decomposition methods, N-mode singular value decomposition (SVD) is widely used owing to its simplicity. However, the data dimension often becomes too large to perform N-mode SVD directly due to memory limitation. An incremental method to N-mode SVD can be used to resolve this issue, but existing approaches only provide a result, which is just enough to solve discriminative problems, not the full factorization result. In this paper, we present a complete derivation of the incremental N-mode SVD, which can be applied to generative models, accompanied by a technique that can reduce the computational cost by reordering calculations. The proposed incremental N-mode SVD can also be used effectively to update the current result of N-mode SVD when new training data is received. The proposed method provides a very good approximation of N -mode SVD for the experimental data, and requires much less computation in updating a multilinear model.

  19. Generating extreme weather event sets from very large ensembles of regional climate models

    Science.gov (United States)

    Massey, Neil; Guillod, Benoit; Otto, Friederike; Allen, Myles; Jones, Richard; Hall, Jim

    2015-04-01

    Generating extreme weather event sets from very large ensembles of regional climate models Neil Massey, Benoit P. Guillod, Friederike E. L. Otto, Myles R. Allen, Richard Jones, Jim W. Hall Environmental Change Institute, University of Oxford, Oxford, UK Extreme events can have large impacts on societies and are therefore being increasingly studied. In particular, climate change is expected to impact the frequency and intensity of these events. However, a major limitation when investigating extreme weather events is that, by definition, only few events are present in observations. A way to overcome this issue it to use large ensembles of model simulations. Using the volunteer distributed computing (VDC) infrastructure of weather@home [1], we run a very large number (10'000s) of RCM simulations over the European domain at a resolution of 25km, with an improved land-surface scheme, nested within a free-running GCM. Using VDC allows many thousands of climate model runs to be computed. Using observations for the GCM boundary forcings we can run historical "hindcast" simulations over the past 100 to 150 years. This allows us, due to the chaotic variability of the atmosphere, to ascertain how likely an extreme event was, given the boundary forcings, and to derive synthetic event sets. The events in these sets did not actually occur in the observed record but could have occurred given the boundary forcings, with an associated probability. The event sets contain time-series of fields of meteorological variables that allow impact modellers to assess the loss the event would incur. Projections of events into the future are achieved by modelling projections of the sea-surface temperature (SST) and sea-ice boundary forcings, by combining the variability of the SST in the observed record with a range of warming signals derived from the varying responses of SSTs in the CMIP5 ensemble to elevated greenhouse gas (GHG) emissions in three RCP scenarios. Simulating the future with a

  20. Physically based modelling of sediment generation and transport under a large rainfall simulator

    Science.gov (United States)

    Adams, Russell; Elliott, Sandy

    2006-07-01

    A series of large rainfall simulator experiments was conducted in 2002 and 2003 on a small plot located in an experimental catchment in the North Island of New Zealand. These experiments measured both runoff and sediment transport under carefully controlled conditions. A physically based hydrological modelling system (SHETRAN) was then applied to reproduce the observed hydrographs and sedigraphs. SHETRAN uses physically based equations to represent flow and sediment transport, and two erodibility coefficients to model detachment of soil particles by raindrop erosion and overland flow erosion. The rate of raindrop erosion also depended on the amount of bare ground under the simulator; this was estimated before each experiment. These erodibility coefficients were calibrated systematically for summer and winter experiments separately, and lower values were obtained for the summer experiments. Earlier studies using small rainfall simulators in the vicinity of the plot also found the soil to be less erodible in summer and autumn. Limited validation of model parameters was carried out using results from a series of autumn experiments. The modelled suspended sediment load was also sensitive to parameters controlling the generation of runoff from the rainfall simulator plot; therefore, we found that accurate runoff predictions were important for the sediment predictions, especially from the experiments where the pasture cover was good and overland flow erosion was the dominant mechanism. The rainfall simulator experiments showed that the mass of suspended sediment increased post-grazing, and according to the model this was due to raindrop detachment. The results indicated that grazing cattle or sheep on steeply sloping hill-country paddocks should be carefully managed, especially in winter, to limit the transport of suspended sediment into watercourses.

  1. NR-PSS (Nonlinear Robust Power System Stabilizer) for large synchronous generators and its large disturbance experiments on real time digital simulator

    Institute of Scientific and Technical Information of China (English)

    LU Qiang; ZHENG ShaoMing; MEI ShengWei; WANG Gang; HUANG QiLi

    2008-01-01

    On the foundation of nonlinear robust control and exact generator model, this paper presents a design principle of NR-PSS (Nonlinear Robust Power System Stabilizer) for multi-machine power system, based on which an industrial NR-PSS equipment is developed. For popularizing it, the proposed parameter setting method of NR-PSS is completely the same as the widely used parameter adjustment rule of PSS. By virtue of real time digital simulator (RTDS), large disturbance experiments are carried out to compare the performances between generator excitation system equipped with NR-PSS and PSS in order to verify the correctness of design theory. The results show that compared with classical PSS, the proposed NR-PSS can dramatically improve the generator damping and attenuate the oscillation much faster, enhance the generator damping and raise both the small signal and large disturbance transient stability transmission power limit remarkably. The NR-PSS equipment with independent intellectual property right has been successfully put into operation on a 300 MW generator in Baishan Hydro Plant of Northeast China Grid more than 10 months.

  2. Game-Theoretic Optimization of Bilateral Contract Transaction for Generation Companies and Large Consumers with Incomplete Information

    Directory of Open Access Journals (Sweden)

    Yi Tang

    2017-06-01

    Full Text Available Bilateral contract transaction among generation companies and large consumers is attracting much attention in the electricity market. A large consumer can purchase energy from generation companies directly under a bilateral contract, which can guarantee the economic interests of both sides. However, in pursuit of more profit, the competitions in the transaction exist not only between the company side and the consumer side, but also among generation companies. In order to maximize its profit, each company needs to optimize bidding price to attract large consumers. In this paper, a master–slave game is proposed to describe the competitions among generation companies and large consumers. Furthermore, a Bayesian game approach is formulated to describe the competitions among generation companies considering the incomplete information. In the model, the goal of each company is to determine the optimal bidding price with Bayesian game; and based on the bidding price provided by companies and the predicted spot price, large consumers decide their personnel purchase strategy to minimize their cost. Simulation results show that each participant in the transaction can benefit from the proposed game.

  3. Can Effective Field Theory of inflation generate large tensor-to-scalar ratio within Randall Sundrum single braneworld?

    CERN Document Server

    Choudhury, Sayantan

    2015-01-01

    In this paper my prime objective is to explain the generation of large tensor-to-scalar ratio from the single field sub-Planckian inflationary paradigm within Randall Sundrum (RS) single braneworld scenario in a model independent fashion. By explicit computation I show that the effective field theory prescription of brane inflation within RS single brane setup is consistent with sub-Planckian excursion of the inflaton field, which will further generate large value of tensor-to-scalar ratio, provided the energy density for inflaton degrees of freedom is high enough compared to the brane tension in high energy regime. Finally, I mention the stringent theoretical constraint on positive brane tension, cut-off of the quantum gravity scale and bulk cosmological constant to get sub-Planckian field excursion along with large tensor-to-scalar ratio as recently observed by BICEP2 or at least generates the tensor-to-scalar ratio consistent with the upper bound of Planck.

  4. Estimating Route Choice Models from Stochastically Generated Choice Sets on Large-Scale Networks Correcting for Unequal Sampling Probability

    DEFF Research Database (Denmark)

    Vacca, Alessandro; Prato, Carlo Giacomo; Meloni, Italo

    2015-01-01

    is the dependency of the parameter estimates from the choice set generation technique. Bias introduced in model estimation has been corrected only for the random walk algorithm, which has problematic applicability to large-scale networks. This study proposes a correction term for the sampling probability of routes...... extracted with stochastic route generation. The term is easily applicable to large-scale networks and various environments, given its dependence only on a random number generator and the Dijkstra shortest path algorithm. The implementation for revealed preferences data, which consist of actual route choices...... collected in Cagliari, Italy, shows the feasibility of generating routes stochastically in a high-resolution network and calculating the correction factor. The model estimation with and without correction illustrates how the correction not only improves the goodness of fit but also turns illogical signs...

  5. Measuring parameters of large-aperture crystals used for generating optical harmonics

    Energy Technology Data Exchange (ETDEWEB)

    English, R. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hibbard, R. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Michie, R. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wegner, P. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Auerbach, J. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Norton, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Summers, M. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Perfect, S. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    1999-02-23

    The purpose of this project was to develop tools for understanding the influence of crystal quality and crystal mounting on harmonic-generation efficiency at high irradiance. Measuring the homogeneity of crystals interferometrically, making detailed physics calculations of conversion efficiency, performing finite- element modeling of mounted crystals, and designing a new optical metrology tool were key elements in obtaining that understanding. For this work, we used the following frequency-tripling scheme: type I second- harmonic generation followed by type II sum-frequency mixing of the residual fundamental and the second harmonic light. The doubler was potassium dihydrogen phosphate (KDP), and the tripler was deuterated KDP (KD*P). With this scheme, near-infrared light (1053 nm) can be frequency tripled (to 351 nm) at high efficiency (theoretically >90%) for high irradiance (>3 GW/cm²). Spatial variations in the birefringence of the large crystals studied here (37 to 41 cm square by about 1 cm thick) imply that the ideal phase-matching orientation of the crystal with respect to the incident laser beam varies across the crystal. We have shown that phase-measuring interferometry can be used to measure these spatial variations. We observed transmitted wavefront differences between orthogonally polarized interferograms of {lambda}/50 to {lambda}/100, which correspond to index variations of order 10-6. On some plates that we measured, the standard deviation of angular errors is 22-23 µrad; this corresponds to a 1% reduction in efficiency. Because these conversion crystals are relatively thin, their surfaces are not flat (deviate by k2.5 urn from flat). A crystal is mounted against a precision-machined surface that supports the crystal on four edges. This mounting surface is not flat either (deviates by +2.5 µm from flat). A retaining flange presses a compliant element against the crystal. The load thus applied near the edges of the crystal surface holds

  6. Improved cost of energy comparison of permanent magnet generators for large offshore wind turbines

    NARCIS (Netherlands)

    Hart, K.; McDonald, A.; Polinder, H.; Corr, E.; Carroll, J.

    2014-01-01

    This paper investigates geared and direct-drive permanent magnet generators for a typical offshore wind turbine, providing a detailed comparison of various wind turbine drivetrain configurations in order to minimise the Cost of Energy. The permanent magnet generator topologies considered include a d

  7. Improved cost of energy comparison of permanent magnet generators for large offshore wind turbines

    NARCIS (Netherlands)

    Hart, K.; McDonald, A.; Polinder, H.; Corr, E.; Carroll, J.

    2014-01-01

    This paper investigates geared and direct-drive permanent magnet generators for a typical offshore wind turbine, providing a detailed comparison of various wind turbine drivetrain configurations in order to minimise the Cost of Energy. The permanent magnet generator topologies considered include a

  8. Large Hadron Collider at CERN: Beams generating high-energy-density matter.

    Science.gov (United States)

    Tahir, N A; Schmidt, R; Shutov, A; Lomonosov, I V; Piriz, A R; Hoffmann, D H H; Deutsch, C; Fortov, V E

    2009-04-01

    This paper presents numerical simulations that have been carried out to study the thermodynamic and hydrodynamic responses of a solid copper cylindrical target that is facially irradiated along the axis by one of the two Large Hadron Collider (LHC) 7 TeV/ c proton beams. The energy deposition by protons in solid copper has been calculated using an established particle interaction and Monte Carlo code, FLUKA, which is capable of simulating all components of the particle cascades in matter, up to multi-TeV energies. These data have been used as input to a sophisticated two-dimensional hydrodynamic computer code BIG2 that has been employed to study this problem. The prime purpose of these investigations was to assess the damage caused to the equipment if the entire LHC beam is lost at a single place. The FLUKA calculations show that the energy of protons will be deposited in solid copper within about 1 m assuming constant material parameters. Nevertheless, our hydrodynamic simulations have shown that the energy deposition region will extend to a length of about 35 m over the beam duration. This is due to the fact that first few tens of bunches deposit sufficient energy that leads to high pressure that generates an outgoing radial shock wave. Shock propagation leads to continuous reduction in the density at the target center that allows the protons delivered in subsequent bunches to penetrate deeper and deeper into the target. This phenomenon has also been seen in case of heavy-ion heated targets [N. A. Tahir, A. Kozyreva, P. Spiller, D. H. H. Hoffmann, and A. Shutov, Phys. Rev. E 63, 036407 (2001)]. This effect needs to be considered in the design of a sacrificial beam stopper. These simulations have also shown that the target is severely damaged and is converted into a huge sample of high-energy density (HED) matter. In fact, the inner part of the target is transformed into a strongly coupled plasma with fairly uniform physical conditions. This work, therefore, has

  9. Tunable narrowband THz pulse generation in scalable large area photoconductive antennas.

    Science.gov (United States)

    Krause, Johannes; Wagner, Martin; Winnerl, Stephan; Helm, Manfred; Stehr, Dominik

    2011-09-26

    The generation and characterization of narrowband THz pulses by means of chirped pulse difference frequency generation in Auston-switch type photoconductive antennas is reported. Using optical pulses with energies in the range from 1 nJ to 1 µJ, we generate THz pulses with up to 50 pJ in energy and electric field strengths on the order of 1 kV/cm. Two emitter concepts are investigated and circumvention of the fast saturation for small area excitation by scaling of the THz emitter is demonstrated.

  10. Large-aperture $Nb_{3}Sn$ quadrupoles for $2^{nd}$ generation LHC IRs

    CERN Document Server

    Zlobin, A V; Chichili, D R; Huang Yu; Kashikhin, V V; Lamm, M J; Limon, P J; Mokhov, N V; Novitski, I; Peterson, T; Strait, J B; Yadav, S

    2002-01-01

    The 1/sup st/ generation of low-beta quadrupoles for the LHC interaction region (IR) was designed to achieve the nominal LHC luminosity of 10/sup 34/ cm/sup -2/s/sup -1/. Given that the lifetime of the 1/sup st/ generation IR quadrupoles is limited by ionizing radiation to 6-7 years, the 2/sup nd/ generation of IR quadrupoles has to be developed with the goal to achieve the ultimate luminosity up to 10/sup 35/ cm/sup -2/s/sup -1/. The IR quadrupole parameters such as nominal gradient, dynamic aperture and physical aperture, operation margins are the main factors limiting the machine performance. Conceptual designs of 90-mm aperture high-gradient quadrupoles, suitable for use in 2/sup nd/ generation high-luminosity LHC IRs with the similar optics, are presented. The issues related to the field gradient, field quality and operation margins are discussed. (5 refs).

  11. A Lightweight, Direct-Drive, Fully Superconducting Generator for Large Wind Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Meinke, Rainer [Advanced Magnet Lab, Palm Bay, FL (United States); Morrison, Darrell [Emerson Inc., St. Louis, MO (United States); Prince, Vernon Gregory [Advanced Magnet Lab, Palm Bay, FL (United States)

    2014-12-31

    The current trend in the offshore wind turbine industry favors direct-drive generators based on permanent magnets, as they allow for a simple and reliable drivetrain without a gearbox. These generators, however, do not scale very well to high power levels beneficial for offshore wind, and their use in wind turbines over 6 MW is questionable in terms of mass and economic feasibility. Moreover, rare earth materials composing the permanent magnets are becoming less available, more costly and potentially unavailable in the foreseeable future. A stated goal of the DOE is a critical materials strategy that pursues the development of substitute materials and technology for rare earth materials to improve supply chain flexibility and meet the needs of the clean energy economy.Therefore, alternative solutions are needed, in terms of both favorable up-scaling and minimizing or eliminating the use of permanent magnets. The generator design presented in this document addresses both these issues with the development of a fully superconducting generator (FSG) with unprecedented high specific torque. A full-scale, 10-MW, 10-rpm generator will weigh less about 150 metric tons, compared to 300 metric tons for an equivalent direct-drive, permanent magnet generator. The developed concept does not use any rare earth materials in its critical drive components, but rather relies on a superconductor composed of mainly magnesium and boron (MgB2), both of which are in abundant supply from multiple global sources.

  12. Large-Scale Multiobjective Static Test Generation for Web-Based Testing with Integer Programming

    Science.gov (United States)

    Nguyen, M. L.; Hui, Siu Cheung; Fong, A. C. M.

    2013-01-01

    Web-based testing has become a ubiquitous self-assessment method for online learning. One useful feature that is missing from today's web-based testing systems is the reliable capability to fulfill different assessment requirements of students based on a large-scale question data set. A promising approach for supporting large-scale web-based…

  13. Large scale single nucleotide polymorphism discovery in unsequenced genomes using second generation high throughput sequencing technology: applied to turkey

    NARCIS (Netherlands)

    Kerstens, H.H.D.; Crooijmans, R.P.M.A.; Veenendaal, A.; Dibbits, B.W.; Chin-A-Woeng, T.F.C.; Dunnen, den J.T.; Groenen, M.A.M.

    2009-01-01

    Background - The development of second generation sequencing methods has enabled large scale DNA variation studies at moderate cost. For the high throughput discovery of single nucleotide polymorphisms (SNPs) in species lacking a sequenced reference genome, we set-up an analysis pipeline based on a

  14. UNIBAB, version 2.2 Monte Carlo event generation for large angle Bhabha scattering at LEP and SLC energies

    CERN Document Server

    Anlauf, H; Manakos, P; Ohl, T

    1995-01-01

    This manual describes version 2.2 of the Monte Carlo event generator UNIBAB for large angle Bhabha scattering at LEP and SLC. UNIBAB implements higher order electromagnetic radiative corrections and the effects of soft photon exponentiation in a photon shower approach. Weak corrections are included through the use of an electroweak library.

  15. Mother Moose Generating Extra Dimensions from Simple Groups at Large N

    CERN Document Server

    Rothstein, I; Rothstein, Ira; Skiba, Witold

    2002-01-01

    We show that there exists a correspondence between four dimensional gauge theories with simple groups and higher dimensional gauge theories at large N. As an example, we show that a four dimensional {N}=2 supersymmetric SU(N) gauge theory, on the Higgs branch, has the same correlators as a five dimensional SU(N) gauge theory in the limit of large N provided the couplings are appropriately rescaled. We show that our results can be applied to the AdS/CFT correspondence to derive correlators of five or more dimensional gauge theories from solutions of five dimensional supergravity in the large t'Hooft coupling limit.

  16. Generation Expansion Planning with Large Amounts of Wind Power via Decision-Dependent Stochastic Programming

    DEFF Research Database (Denmark)

    Zhan, Yiduo; Zheng, Qipeng; Wang, Jianhui

    2016-01-01

    , the probability distribution function is determined by not only input parameters but also decision variables. To deal with the nonlinear constraints in our model, a quasi-exact solution approach is then introduced to reformulate the multistage stochastic investment model to a mixed-integer linear programming......Power generation expansion planning needs to deal with future uncertainties carefully, given that the invested generation assets will be in operation for a long time. Many stochastic programming models have been proposed to tackle this challenge. However, most previous works assume predetermined...

  17. Interspecies chimeric complementation for the generation of functional human tissues and organs in large animal hosts.

    Science.gov (United States)

    Wu, Jun; Izpisua Belmonte, Juan Carlos

    2016-06-01

    The past decade's rapid progress in human pluripotent stem cell (hPSC) research has generated hope for meeting the rising demand of organ donation, which remains the only effective cure for end-stage organ failure, a major cause of death worldwide. Despite the potential, generation of transplantable organs from hPSCs using in vitro differentiation is far-fetched. An in vivo interspecies chimeric complementation strategy relying on chimeric-competent hPSCs and zygote genome editing provides an auspicious alternative for providing unlimited organ source for transplantation.

  18. Timetable-based simulation method for choice set generation in large-scale public transport networks

    DEFF Research Database (Denmark)

    Rasmussen, Thomas Kjær; Anderson, Marie Karen; Nielsen, Otto Anker

    2016-01-01

    The composition and size of the choice sets are a key for the correct estimation of and prediction by route choice models. While existing literature has posed a great deal of attention towards the generation of path choice sets for private transport problems, the same does not apply to public...... transport problems. This study proposes a timetable-based simulation method for generating path choice sets in a multimodal public transport network. Moreover, this study illustrates the feasibility of its implementation by applying the method to reproduce 5131 real-life trips in the Greater Copenhagen Area...

  19. Prospects for generating electricity by large onshore and offshore wind farms

    DEFF Research Database (Denmark)

    Volker, Patrick; Hahmann, Andrea N.; Badger, Jake

    2017-01-01

    The decarbonisation of energy sources requires additional investments in renewable technologies, including the installation of onshore and offshore wind farms. For wind energy to remain competitive, wind farms must continue to provide low-cost power even when covering larger areas. Inside very la...... regions with moderate winds offer potential locations for very large wind farms. In offshore regions, clusters of smaller wind farms are generally preferable; under very strong winds also very large offshore wind farms become efficient....

  20. Prospects for generating electricity by large onshore and offshore wind farms

    Science.gov (United States)

    Volker, Patrick J. H.; Hahmann, Andrea N.; Badger, Jake; Jørgensen, Hans E.

    2017-03-01

    The decarbonisation of energy sources requires additional investments in renewable technologies, including the installation of onshore and offshore wind farms. For wind energy to remain competitive, wind farms must continue to provide low-cost power even when covering larger areas. Inside very large wind farms, winds can decrease considerably from their free-stream values to a point where an equilibrium wind speed is reached. The magnitude of this equilibrium wind speed is primarily dependent on the balance between turbine drag force and the downward momentum influx from above the wind farm. We have simulated for neutral atmospheric conditions, the wind speed field inside different wind farms that range from small (25 km2) to very large (105 km2) in three regions with distinct wind speed and roughness conditions. Our results show that the power density of very large wind farms depends on the local free-stream wind speed, the surface characteristics, and the turbine density. In onshore regions with moderate winds the power density of very large wind farms reaches 1 W m‑2, whereas in offshore regions with very strong winds it exceeds 3 W m‑2. Despite a relatively low power density, onshore regions with moderate winds offer potential locations for very large wind farms. In offshore regions, clusters of smaller wind farms are generally preferable; under very strong winds also very large offshore wind farms become efficient.

  1. Dual branch high voltage pulse generator for the beam extraction of the Large Hadron Collider

    CERN Document Server

    Bonthond, J; Ducimetière, L; Jansson, U; Vossenberg, Eugène B

    2002-01-01

    The LHC beam extraction kicker system, MKD, is composed of 15 fast kicker magnets per beam to extract the particles in one turn from the collider and to dispose them, after dilution, on an external absorber. Each magnet is powered by a separate pulse generator. The original single branch generator consisted of a discharge capacitor in series with a solid state closing switch left bracket 1 right bracket operating at 30 kV. In combination with a parallel freewheel diode stack this generator produced a current pulse of 2.7 mus rise time, 18.5 kA amplitude and about 1.8 ms fall time, of which only about 90 mus are needed to dump the beam. The freewheel diode circuit is equipped with a flat top current droop compensation network, consisting of a low voltage, low stray inductance, high current discharge capacitor. Extensive reliability studies have meanwhile suggested to further increase the operational safety of this crucial system by equipping each generator with two parallel branches. This paper presents the re...

  2. Combining Compact Representation and Incremental Generation in Large Games with Sequential Strategies

    DEFF Research Database (Denmark)

    Bosansky, Branislav; Xin Jiang, Albert; Tambe, Milind

    2015-01-01

    with incremental strategy generation. We experimentally compare CS-DO with the standard approaches and analyze the impact of the size of the support on the performance of the algorithms. Results show that CS-DO dramatically improves the convergence rate in games with non-trivial support...... representation of sequential strategies and linear programming, or by incremental strategy generation of iterative double-oracle methods. In this paper, we present novel hybrid of these two approaches: compact-strategy double-oracle (CS-DO) algorithm that combines the advantages of the compact representation......Many search and security games played on a graph can be modeled as normal-form zero-sum games with strategies consisting of sequences of actions. The size of the strategy space provides a computational challenge when solving these games. This complexity is tackled either by using the compact...

  3. Ultraheavy Yukawa-bound states of fourth-generation at Large Hadron Collider

    Indian Academy of Sciences (India)

    Ts Enkhbat

    2012-10-01

    A study of bound states of the fourth-generation quarks in the range of 500–700 GeV is presented, where the binding energies are expected to be mainly of Yukawa origin, with QCD subdominant. Near degeneracy of their masses exhibits a new `isospin'. The production of a colour- octet, isosinglet vector meson via $q\\bar{q} → g$ is the most interesting. Its leading decay modes are $_{8}^{±} W^{\\mp}$, $_{8}^{0} Z^{0}$, and constituent quark decay, with $q\\bar{q}$ and $t\\bar{t'}$ and $b\\bar{b'}$ subdominant. The colour octet, isovector pseudoscalar 8 meson decays via constituent quark decay, or to $W g$. This work calls for more detailed study of fourth-generation phenomena at LHC.

  4. Contribution of energy storage for large-scale integration of variable generation

    Energy Technology Data Exchange (ETDEWEB)

    Estanqueiro, Ana [National Laboratory for Energy and Geology (LNEG), Lisbon (Portugal); Aardal, Atle Rygg [SINTEF, Trondheim (Norway); O' Dwyer, Ciara [University College Dublin (UCD) (Ireland)] [and others

    2012-07-01

    The amount of wind power and other time-variable non-dispatchable renewable energy sources (VRES) such as photovoltaics (PV) is rapidly increasing in the world. Several power systems in Europe are already facing a very high penetration from variable renewables which is posing concerns on the operational stability limits that are being surpassed for extreme RES generation conditions. Most transmission system operators are defining VRES limits of penetration, thus, requiring the renewable energy excess to be curtailed, exported or stored. Energy storage may play a relevant role in maximizing the long term penetration of VRES if used as a technical mean to regulate the daily, weekly and annual profiles of variable generation (VG). This paper reviews the storage technologies that are available and may be used on a power system scale and performs a cost/benefit analysis discussing their advantages and disadvantages for the integration of fast-growing renewables, such as wind power and PV. (orig.)

  5. Gauge Field Generation on Large-Scale GPU-Enabled Systems

    CERN Document Server

    Winter, Frank

    2012-01-01

    Over the past years GPUs have been successfully applied to the task of inverting the fermion matrix in lattice QCD calculations. Even strong scaling to capability-level supercomputers, corresponding to O(100) GPUs or more has been achieved. However strong scaling a whole gauge field generation algorithm to this regim requires significantly more functionality than just having the matrix inverter utilizing the GPUs and has not yet been accomplished. This contribution extends QDP-JIT, the migration of SciDAC QDP++ to GPU-enabled parallel systems, to help to strong scale the whole Hybrid Monte-Carlo to this regime. Initial results are shown for gauge field generation with Chroma simulating pure Wilson fermions on OLCF TitanDev.

  6. FUNDAMENTAL RESONANCE AND BIFURCATION OF LARGE GENERATOR END WINDING WHEN ITS CLAMPING PLATES ARE LOOSE

    Institute of Scientific and Technical Information of China (English)

    HU Yu-da; QIU Jia-jun; TA Na

    2005-01-01

    Vibration problems of a segment of winding between two clamping plates are studied when the clamping plates, which are used to fix stator end winding, are loose. First,magnetic induction expressions of the winding while the generator was running were given by using separation of variables method. Also, the expressions of the winding electromagnetic force and dry friction force between loosing clamping plates were gotten. Secondly, a mechanical model, which was used to study nonlinear vibration problem of the winding, was set up. Fundamental resonance was analyzed by using multiple scales method, and a resonance equation of amplitude and frequency in steady state was given. Then stability,bifurcation and singularity of the steady solution were studied. Criterions of stability and transition set of the bifurcation equation were obtained. At last, through numerical calculations, resonance curves were obtained. The results are helpful for analysis and protection of generator accidents.

  7. Primary shunt hyperbilirubinaemia in a large four-generation family confirming autosomal dominant genetic disorder

    Institute of Scientific and Technical Information of China (English)

    Chun-Lian Wang; Xiao-Wei Liu; Fang-Gen Lu; Xiao-Ping Wu; Chun-Hui Ouyang; Dong-Ye Yang

    2006-01-01

    AIM: To describe the pattern of inheritance and confirm the diagnosdc criteria of primary shunt hyperbilirubinaemia (PSH).METHODS: Forty members of a family pedigree across four generations were included in this study. All family members were interviewed and investigated by physical examination, hematology and liver function test and the pattern of inheritance was analyzed.RESULTS: Nine of the forty family members suffered primary shunt hyperbilirubinaemia. The mature erythrocytes of the propositus were irregular in shape and size.The pedigree showed transmission of the trait through four generations with equal distribution in male and female. No individual with a primary shunt hyperbilirubinaemia was born to unaffected parents. The penetrance was complete in adult.CONCLUSION: The pattern of inheritance is autosomal dominant. The abnormality of erythrocytes and decrease in white blood cell could be supplemented in the diagnosis of PSH. The PSH is a genetic disorder and could by renamed as hereditary shunt hyperbilirubinaemia.

  8. Z-DNA-forming sequences generate large-scale deletions in mammalian cells

    OpenAIRE

    Wang, Guliang; Christensen, Laura A.; Vasquez, Karen M.

    2006-01-01

    Spontaneous chromosomal breakages frequently occur at genomic hot spots in the absence of DNA damage and can result in translocation-related human disease. Chromosomal breakpoints are often mapped near purine–pyrimidine Z-DNA-forming sequences in human tumors. However, it is not known whether Z-DNA plays a role in the generation of these chromosomal breakages. Here, we show that Z-DNA-forming sequences induce high levels of genetic instability in both bacterial and mammalian cells. In mammali...

  9. Generation of Comprehensive Surrogate Kinetic Models and Validation Databases for Simulating Large Molecular Weight Hydrocarbon Fuels

    Science.gov (United States)

    2012-10-25

    composed of highly isomerized paraffinic kerosene (denoted IPK). Comparisons of a 2nd generation surrogate formulated to match all four of the above...and di methyl alkanes was emulated using mixtures of n-dodecane and iso-octane that replicated its combustion property targets, demonstrating that... methyl heptane was shown to replicate the global combustion properties of the weakly branched isomer, further supporting that distinct functional

  10. Efficiency and economics of large scale hydrogen liquefaction. [for future generation aircraft requirements

    Science.gov (United States)

    Baker, C. R.

    1975-01-01

    Liquid hydrogen is being considered as a substitute for conventional hydrocarbon-based fuels for future generations of commercial jet aircraft. Its acceptance will depend, in part, upon the technology and cost of liquefaction. The process and economic requirements for providing a sufficient quantity of liquid hydrogen to service a major airport are described. The design is supported by thermodynamic studies which determine the effect of process arrangement and operating parameters on the process efficiency and work of liquefaction.

  11. The Generation of a Large-Scale Galactic Magnetic Field by Electric Currents of Energetic Particles

    Science.gov (United States)

    Dolginov, A. Z.; Toptygin, I. N.

    2003-06-01

    We consider the generation of a magnetic field in the Galaxy by the electric currents excited by cosmic-ray particles in the disk and halo. We assume that the sources of relativistic particles are distributed continuously and uniformly in the Galactic disk, their total power is equal to the observed value, and the particles themselves undergo anisotropic diffusion in a homogeneous medium. We take into account the differential rotation of the Galactic disk but disregard the turbulence gyrotropy (the alpha-effect). The strength of the generated magnetic field in our model is shown to strongly depend on the symmetry of the relativistic proton and thermal electron diffusion tensors, as well as on the relations between the tensor components. In particular, if the diffusion is isotropic, then no magnetic field is generated. For the independent tensor components estimated from observed parameters of the Galactic medium and with a simultaneous allowance made for the turbulent field dissipation processes, the mechanism under consideration can provide an observable magnetic-field strength of the order of several microgauss. This mechanism does not require any seed magnetic field, which leads us to suggest that relativistic particles can give an appreciable and, possibly, determining contribution to the formation of the global Galactic magnetic field. However, a final answer can be obtained only from a nonlinear self-consistent treatment, in which the symmetry and magnitude of the particle diffusion tensor components should be determined together with the calculation of the magnetic field.

  12. Self-Tuning Linear Quadratic Supervisory Regulation of a Diesel Generator using Large-Signal State Estimation

    DEFF Research Database (Denmark)

    Knudsen, Jesper Viese; Bendtsen, Jan Dimon; Andersen, Palle;

    2016-01-01

    In this paper, a self-tuning linear quadratic supervisory regulator using a large-signal state estimator for a diesel driven generator set is proposed. The regulator improves operational efficiency, in comparison to current implementations, by (i) automating the initial tuning process and (ii......) enabling automated retuning capabilities. Utilizing a first principles-based nonlinear model detailed in [1], the procedure is demonstrated through simulations after real system measurements have been used for parameter identification. The regulator is able to suppress load-induced variations successfully...... throughout the operating range of the diesel generator....

  13. Efficient Mid-Infrared Supercontinuum Generation in Tapered Large Mode Area Chalcogenide Photonic Crystal Fibers

    DEFF Research Database (Denmark)

    Petersen, Christian Rosenberg; Engelsholm, Rasmus Dybbro; Markos, Christos

    2017-01-01

    Mid-infrared supercontinuum spanning from 1.8-9  μm with an output power of 41.5 mW is demonstrated by pumping tapered large mode area chalcogenide photonic crystal fibers using a 4 μm optical parametric source....

  14. Potential vertical movement of large heat-generating waste packages in salt.

    Energy Technology Data Exchange (ETDEWEB)

    Clayton, Daniel James; Martinez, Mario J.; Hardin, Ernest.

    2013-05-01

    With renewed interest in disposal of heat-generating waste in bedded or domal salt formations, scoping analyses were conducted to estimate rates of waste package vertical movement. Vertical movement is found to result from thermal expansion, from upward creep or heave of the near-field salt, and from downward buoyant forces on the waste package. A two-pronged analysis approach was used, with thermal-mechanical creep modeling, and coupled thermal-viscous flow modeling. The thermal-mechanical approach used well-studied salt constitutive models, while the thermal-viscous approach represented the salt as a highly viscous fluid. The Sierra suite of coupled simulation codes was used for both approaches. The waste package in all simulations was a right-circular cylinder with the density of steel, in horizontal orientation. A time-decaying heat generation function was used to represent commercial spent fuel with typical burnup and 50-year age. Results from the thermal-mechanical base case showed approximately 27 cm initial uplift of the package, followed by gradual relaxation closely following the calculated temperature history. A similar displacement history was obtained with the package density set equal to that of salt. The slight difference in these runs is attributable to buoyant displacement (sinking) and is on the order of 1 mm in 2,000 years. Without heat generation the displacement stabilizes at a fraction of millimeter after a few hundred years. Results from thermal-viscous model were similar, except that the rate of sinking was constant after cooldown, at approximately 0.15 mm per 1,000 yr. In summary, all calculations showed vertical movement on the order of 1 mm or less in 2,000 yr, including calculations using well-established constitutive models for temperature-dependent salt deformation. Based on this finding, displacement of waste packages in a salt repository is not a significant repository performance issue.

  15. Fast Generation of Near-Optimal Plans for Eco-Efficient Stowage of Large Container Vessels

    DEFF Research Database (Denmark)

    Pacino, Dario; Delgado, Alberto; Jensen, Rune Møller

    2011-01-01

    Eco-efficient stowage plans that are both competitive and sustainable have become a priority for the shipping industry. Stowage planning is NP-hard and is a challenging optimization problem in practice. We propose a new 2-phase approach that generates near-optimal stowage plans and fulfills indus...... industrial time and quality requirements. Our approach combines an integer programming model for assigning groups of containers to storage areas of the vessel over multiple ports, and a constraint programming and local search procedure for stowing individual containers....

  16. Economical evaluation of large-scale photovoltaic systems using Universal Generating Function techniques

    DEFF Research Database (Denmark)

    Ding, Yi; Shen, Weixiang; Levitin, Gregory

    2013-01-01

    . The reliability models of solar panel arrays, PV inverters and energy production units (EPUs) are represented as the corresponding UGFs. The expected energy production models for different PV system configurations have also been developed. The expected unit cost of electricity has been calculated to provide......Solar energy plays an important role in the global energy framework for future. Comparing with conventional generation systems using fossil fuels, the cost structure of photovoltaic (PV) systems is different: the capital cost is higher while the operation cost is negligible. Reliabilities of the PV...

  17. Generation of low-frequency electric and magnetic fields during large- scale chemical and nuclear explosions

    Energy Technology Data Exchange (ETDEWEB)

    Adushkin, V.V. [Academy of Sciences, Moscow (Russian Federation). Inst. for Dynamics of the Geospheres; Dubinya, V.A.; Karaseva, V.A.; Soloviev, S.P.; Surkov, V.V. [Lawrence Livermore National Lab., CA (United States)

    1995-06-01

    We discuss the main parameters of the electric field in the surface layer of the atmosphere and the results of the investigations of the natural electric field variations. Experimental investigations of the electromagnetic field for explosions in air are presented. Electromagnetic signals generated by underground nuclear and chemical explosions are discussed and explosions for 1976--1991 are listed. Long term anomalies of the earth`s electromagnetic field in the vicinity of underground explosions were also investigated. Study of the phenomenon of the irreversible shock magnetization showed that in the zone nearest to the explosion the quasistatic magnetic field decreases in inverse proportion to the distance.

  18. Fast Generation of Near-Optimal Plans for Eco-Efficient Stowage of Large Container Vessels

    DEFF Research Database (Denmark)

    Pacino, Dario; Jensen, Rune Møller; Delgado-Ortegon, Alberto

    2011-01-01

    Eco-Efficient stowage plans that are both competitive and sustainable have become a priority for the shipping industry. Stowage planning is NP-hard and is a challenging optimization problem in practice. We propose a new 2-phase approach that generates near-optimal stowage plans and fulfills indus...... industrial time and quality requirements. Our approach combines an integer programming model for assigning groups of containers to storage areas of the vessel over multiple ports, and a constraint programming and local search procedure for stowing individual containers....

  19. Maximal aerobic and anaerobic power generation in large crocodiles versus mammals: implications for dinosaur gigantothermy.

    Directory of Open Access Journals (Sweden)

    Roger S Seymour

    Full Text Available Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic.

  20. Maximal aerobic and anaerobic power generation in large crocodiles versus mammals: implications for dinosaur gigantothermy.

    Science.gov (United States)

    Seymour, Roger S

    2013-01-01

    Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic.

  1. Spontaneous large-scale autolysis in Clostridium acetobutylicum contributes to generation of more spores

    OpenAIRE

    Zhen eLiu; Kai eQiao; Lei eTian; Quan eZhang; Zi-Yong eLiu; Fu-Li eLi

    2015-01-01

    Autolysis is a widespread phenomenon in bacteria. In batch fermentation of Clostridium acetobutylicum ATCC 824, there is a spontaneous large-scale autolysis phenomenon with significant decrease of cell density immediately after exponential phase. To unravel the role of autolysis, an autolysin-coding gene, CA_C0554, was disrupted by using ClosTron system to obtain the mutant C. acetobutylicum lyc::int(72). The lower final cell density and faster cell density decrease rate of C. acetobutylicum ...

  2. Blasting Vibration Generated by Breaking-Blasting Large Barriers with EBBLB

    OpenAIRE

    Wang Zhen-xiong; Gu Wen-bin; Liang Ting; Liu Jian-qing; Xu Jing-lin; Liu Xin

    2016-01-01

    Equipment for breaking and blasting large barriers (EBBLB) is new break-blast equipment, which inevitably induces ground vibration and may cause substantial damage to rock mass and nearby structures as well as human beings. The ground vibration induced by break-blast is one of the inevitable outcomes. By monitoring vibration at measuring points at different distances from blasting center, time history curve of vibrating velocity can be obtained; it can be drawn that blasting seismic waves are...

  3. Experimental investigation of the generation of large-amplitude internal solitary wave and its interaction with a submerged slender body

    Science.gov (United States)

    Wei, Gang; Du, Hui; Xu, XiaoHui; Zhang, YuanMing; Qu, ZiYun; Hu, TianQun; You, YunXiang

    2014-01-01

    A principle of generating the nonlinear large-amplitude internal wave in a stratified fluid tank with large cross-section is proposed according to the `jalousie' control mode. A new wave-maker based on the principle was manufactured and the experiments on the generation and evolution of internal solitary wave were conducted. Both the validity of the new device and applicability range of the KdV-type internal soliton theory were tested. Furthermore, a measurement technique of hydrodynamic load of internal waves was developed. By means of accurately measuring slight variations of internal wave forces exerted on a slender body in the tank, their interaction characteristics were determined. It is shown that through establishing the similarity between the model scale in the stratified fluid tank and the full scale in the numerical simulation the obtained measurement results of internal wave forces are confirmed to be correct.

  4. Wind power integration into the automatic generation control of power systems with large-scale wind power

    DEFF Research Database (Denmark)

    Basit, Abdul; Hansen, Anca Daniela; Altin, Müfit

    2014-01-01

    Transmission system operators have an increased interest in the active participation of wind power plants (WPP) in the power balance control of power systems with large wind power penetration. The emphasis in this study is on the integration of WPPs into the automatic generation control (AGC......) of the power system. The present paper proposes a coordinated control strategy for the AGC between combined heat and power plants (CHPs) and WPPs to enhance the security and the reliability of a power system operation in the case of a large wind power penetration. The proposed strategy, described...... and exemplified for the future Danish power system, takes the hour-ahead regulating power plan for generation and power exchange with neighbouring power systems into account. The performance of the proposed strategy for coordinated secondary control is assessed and discussed by means of simulations for different...

  5. ActivitySim: large-scale agent based activity generation for infrastructure simulation

    Energy Technology Data Exchange (ETDEWEB)

    Gali, Emmanuel [Los Alamos National Laboratory; Eidenbenz, Stephan [Los Alamos National Laboratory; Mniszewski, Sue [Los Alamos National Laboratory; Cuellar, Leticia [Los Alamos National Laboratory; Teuscher, Christof [PORTLAND STATE UNIV

    2008-01-01

    The United States' Department of Homeland Security aims to model, simulate, and analyze critical infrastructure and their interdependencies across multiple sectors such as electric power, telecommunications, water distribution, transportation, etc. We introduce ActivitySim, an activity simulator for a population of millions of individual agents each characterized by a set of demographic attributes that is based on US census data. ActivitySim generates daily schedules for each agent that consists of a sequence of activities, such as sleeping, shopping, working etc., each being scheduled at a geographic location, such as businesses or private residences that is appropriate for the activity type and for the personal situation of the agent. ActivitySim has been developed as part of a larger effort to understand the interdependencies among national infrastructure networks and their demand profiles that emerge from the different activities of individuals in baseline scenarios as well as emergency scenarios, such as hurricane evacuations. We present the scalable software engineering principles underlying ActivitySim, the socia-technical modeling paradigms that drive the activity generation, and proof-of-principle results for a scenario in the Twin Cities, MN area of 2.6 M agents.

  6. Generating Representative Sets and Summaries for Large Collection of Images Using Image Cropping Techniques and Result Comparison

    Directory of Open Access Journals (Sweden)

    Abdullah Al-Mamun

    2015-11-01

    Full Text Available The collection of photos hosted on photo archives and social networking sites has been increasing exponentially. It is really hard to get the summary of a large image set without browsing through the entire collection. In this paper two different techniques of image cropping (random windows technique and sequential windows technique have been proposed to generate effective representative sets. A ranking mechanism has been also proposed for finding the best representative set.

  7. Can Effective Field Theory of inflation generate large tensor-to-scalar ratio within Randall–Sundrum single braneworld?

    Directory of Open Access Journals (Sweden)

    Sayantan Choudhury

    2015-05-01

    Full Text Available In this paper my prime objective is to explain the generation of large tensor-to-scalar ratio from the single field sub-Planckian inflationary paradigm within Randall–Sundrum (RS single braneworld scenario in a model independent fashion. By explicit computation I have shown that the effective field theory prescription of brane inflation within RS single brane setup is consistent with sub-Planckian excursion of the inflaton field, which will further generate large value of tensor-to-scalar ratio, provided the energy density for inflaton degrees of freedom is high enough compared to the brane tension in high energy regime. Finally, I have mentioned the stringent theoretical constraint on positive brane tension, cut-off of the quantum gravity scale and bulk cosmological constant to get sub-Planckian field excursion along with large tensor-to-scalar ratio as recently observed by BICEP2 or at least generates the tensor-to-scalar ratio consistent with the upper bound of Planck (2013 and 2015 data and Planck+BICEP2+Keck Array joint constraint.

  8. Can Effective Field Theory of inflation generate large tensor-to-scalar ratio within Randall–Sundrum single braneworld?

    Energy Technology Data Exchange (ETDEWEB)

    Choudhury, Sayantan, E-mail: sayanphysicsisi@gmail.com

    2015-05-15

    In this paper my prime objective is to explain the generation of large tensor-to-scalar ratio from the single field sub-Planckian inflationary paradigm within Randall–Sundrum (RS) single braneworld scenario in a model independent fashion. By explicit computation I have shown that the effective field theory prescription of brane inflation within RS single brane setup is consistent with sub-Planckian excursion of the inflaton field, which will further generate large value of tensor-to-scalar ratio, provided the energy density for inflaton degrees of freedom is high enough compared to the brane tension in high energy regime. Finally, I have mentioned the stringent theoretical constraint on positive brane tension, cut-off of the quantum gravity scale and bulk cosmological constant to get sub-Planckian field excursion along with large tensor-to-scalar ratio as recently observed by BICEP2 or at least generates the tensor-to-scalar ratio consistent with the upper bound of Planck (2013 and 2015) data and Planck+BICEP2+Keck Array joint constraint.

  9. Bone tissue phantoms for optical flowmeters at large interoptode spacing generated by 3D-stereolithography.

    Science.gov (United States)

    Binzoni, Tiziano; Torricelli, Alessandro; Giust, Remo; Sanguinetti, Bruno; Bernhard, Paul; Spinelli, Lorenzo

    2014-08-01

    A bone tissue phantom prototype allowing to test, in general, optical flowmeters at large interoptode spacings, such as laser-Doppler flowmetry or diffuse correlation spectroscopy, has been developed by 3D-stereolithography technique. It has been demonstrated that complex tissue vascular systems of any geometrical shape can be conceived. Absorption coefficient, reduced scattering coefficient and refractive index of the optical phantom have been measured to ensure that the optical parameters reasonably reproduce real human bone tissue in vivo. An experimental demonstration of a possible use of the optical phantom, utilizing a laser-Doppler flowmeter, is also presented.

  10. Generation of large-scale maps of science and associated indicators.

    Energy Technology Data Exchange (ETDEWEB)

    Klavans, Richard (SciTech Strategies, Inc., Berwyn, PA); Boyack, Kevin W.

    2005-12-01

    Over the past several years, techniques have been developed for clustering very large segments of the technical literature using sources such as Thomson ISI's Science Citation Index. The primary objective of this work has been to develop indicators of potential impact at the paper level to enhance planning and evaluation of research. These indicators can also be aggregated at different levels to enable profiling of departments, institutions, agencies, etc. Results of this work are presented as maps of science and technology with various overlays corresponding to the indicators associated with a particular search or question.

  11. Very large optical rotation generated by Rb vapor in a multi-pass cell

    CERN Document Server

    Li, S; Sheng, D; Dural, N; Romalis, M V

    2011-01-01

    Paramagnetic Faraday rotation is a powerful technique for atom sensing widely used in quantum non-demolition measurements, fundamental symmetry tests, and other precision measurements. We demonstrate the use of a multi-pass optical cell for Faraday rotation spectroscopy and observe polarization rotation in excess of 100 radians from spin-polarized Rb vapor. Unlike optical cavities, multi-pass cells have a deterministic number of light passes and can be used to measure large optical rotations. We also observe a 10-fold suppression of transverse spin relaxation when Rb atoms are placed in a coherent superposition state immune to spin-exchange collisions.

  12. Potential benefits of a ceramic thermal barrier coating on large power generation gas turbine

    Science.gov (United States)

    Clark, J. S.; Nainiger, J. J.

    1977-01-01

    Thermal barrier coating design option offers benefit in terms of reduced electricity costs when used in utility gas turbines. Options considered include: increased firing temperature, increased component life, reduced cooling air requirements, and increased corrosion resistance (resulting in increased tolerance for dirty fuels). Performance and cost data were obtained. Simple, recuperated and combined cycle applications were considered, and distillate and residual fuels were assumed. The results indicate that thermal barrier coatings could produce large electricity cost savings if these coatings permit turbine operation with residual fuels at distillate-rated firing temperatures. The results also show that increased turbine inlet temperature can result in substantial savings in fuel and capital costs.

  13. Feasibility of large-scale calorimetric efficiency measurement for wind turbine generator drivetrains

    Science.gov (United States)

    Pagitsch, Michael; Jacobs, Georg; Schelenz, Ralf; Bosse, Dennis; Liewen, Christian; Reisch, Sebastian; Deicke, Matthias

    2016-09-01

    In the course of the global energy turnaround, the importance of wind energy is increasing continuously. For making wind energy more competitive with fossil energy, reducing the costs is an important measure. One way to reach this goal is to improve the efficiency. As the major potentials have already been exploited, improvements in the efficiency are made in small steps. One of the main preconditions for enabling these development activities is the sufficiently accurate measurement of the efficiency. This paper presents a method for measuring the efficiency of geared wind turbine generator drivetrains with errors below 0.5% by directly quantifying the power losses. The presented method is novel for wind turbines in the multi- MW-class.

  14. High-throughput film-densitometry: An efficient approach to generate large data sets

    Energy Technology Data Exchange (ETDEWEB)

    Typke, Dieter; Nordmeyer, Robert A.; Jones, Arthur; Lee, Juyoung; Avila-Sakar, Agustin; Downing, Kenneth H.; Glaeser, Robert M.

    2004-07-14

    A film-handling machine (robot) has been built which can, in conjunction with a commercially available film densitometer, exchange and digitize over 300 electron micrographs per day. Implementation of robotic film handling effectively eliminates the delay and tedium associated with digitizing images when data are initially recorded on photographic film. The modulation transfer function (MTF) of the commercially available densitometer is significantly worse than that of a high-end, scientific microdensitometer. Nevertheless, its signal-to-noise ratio (S/N) is quite excellent, allowing substantial restoration of the output to ''near-to-perfect'' performance. Due to the large area of the standard electron microscope film that can be digitized by the commercial densitometer (up to 10,000 x 13,680 pixels with an appropriately coded holder), automated film digitization offers a fast and inexpensive alternative to high-end CCD cameras as a means of acquiring large amounts of image data in electron microscopy.

  15. Kinetic Alfv\\'en waves generation by large-scale phase-mixing

    CERN Document Server

    Vasconez, C L; Valentini, F; Servidio, S; Matthaeus, W H; Malara, F

    2015-01-01

    One view of the solar-wind turbulence is that the observed highly anisotropic fluctuations at spatial scales near the proton inertial length $d_p$ may be considered as Kinetic Alfv\\'en waves (KAWs). In the present paper, we show how phase-mixing of large-scale parallel propagating Alfv\\'en waves is an efficient mechanism for the production of KAWs at wavelengths close to $d_p$ and at large propagation angle with respect to the magnetic field. Magnetohydrodynamic (MHD), Hall-Magnetohydrodynamic (HMHD), and hybrid Vlasov-Maxwell (HVM) simulations modeling the propagation of Alfv\\'en waves in inhomogeneous plasmas are performed. In linear regime, the role of dispersive effects is singled out by comparing MHD and HMHD results. Fluctuations produced by phase-mixing are identified as KAWs through a comparison of polarization of magnetic fluctuations and wave group velocity with analytical linear predictions. In the nonlinear regime, comparison of HMHD and HVM simulations allows to point out the role of kinetic effe...

  16. Method for Generating Frequent Landsat-like NDVI Datasets in Large Areas

    Science.gov (United States)

    Song, J.; Liao, L.; Wang, J.; Wu, Q.; Yu, B.

    2016-12-01

    In order to get reliable high spatial and temporal resolution Normalized Difference Vegetation Index (NDVI) datasets to support other land surface process studies, we propose a new method for accurately and effectively building frequent high spatial resolution Landsat-like NDVI datasets by integrating Moderate Resolution Imaging Spectroradiometer (MODIS) and Landsat NDVI. The implementation of the proposed method mainly includes two steps. First, the MODIS NDVI was downscaled into the Landsat resolution, and then an prediction model was applied to combine the downscaled MODIS NDVI and Landsat NDVI observations to obtain the Landsat-like NDVI estimators. Experiment in a large-scale area was conducted, and the results comparing with the Spatial and Temporal Adaptive Reflectance Fusion Model showed that our proposed method can achieve more accurate estimates with more spatial details, and its prediction accuracy is less dependent on the quality of the MODIS NDVI on the specific prediction date. These features suggested that the proposed method was more applicable in mass NDVI production in large areas. However, the proposed method also has limitations on computation and automation, and future studies should focus on simplifying the current method. In summery, this study provides a new data fusion algorithm, which may contribute to applications that require NDVI products with both high spatial resolution and frequent coverage.

  17. On the generation of magnetized collisionless shocks in the large plasma device

    Science.gov (United States)

    Schaeffer, D. B.; Winske, D.; Larson, D. J.; Cowee, M. M.; Constantin, C. G.; Bondarenko, A. S.; Clark, S. E.; Niemann, C.

    2017-04-01

    Collisionless shocks are common phenomena in space and astrophysical systems, and in many cases, the shocks can be modeled as the result of the expansion of a magnetic piston though a magnetized ambient plasma. Only recently, however, have laser facilities and diagnostic capabilities evolved sufficiently to allow the detailed study in the laboratory of the microphysics of piston-driven shocks. We review experiments on collisionless shocks driven by a laser-produced magnetic piston undertaken with the Phoenix laser laboratory and the Large Plasma Device at the University of California, Los Angeles. The experiments span a large parameter space in laser energy, background magnetic field, and ambient plasma properties that allow us to probe the physics of piston-ambient energy coupling, the launching of magnetosonic solitons, and the formation of subcritical shocks. The results indicate that piston-driven magnetized collisionless shocks in the laboratory can be characterized with a small set of dimensionless formation parameters that place the formation process in an organized and predictive framework.

  18. Next Generation Heavy-Lift Launch Vehicle: Large Diameter, Hydrocarbon-Fueled Concepts

    Science.gov (United States)

    Holliday, Jon; Monk, Timothy; Adams, Charles; Campbell, Ricky

    2012-01-01

    With the passage of the 2010 NASA Authorization Act, NASA was directed to begin the development of the Space Launch System (SLS) as a follow-on to the Space Shuttle Program. The SLS is envisioned as a heavy lift launch vehicle that will provide the foundation for future large-scale, beyond low Earth orbit (LEO) missions. Supporting the Mission Concept Review (MCR) milestone, several teams were formed to conduct an initial Requirements Analysis Cycle (RAC). These teams identified several vehicle concept candidates capable of meeting the preliminary system requirements. One such team, dubbed RAC Team 2, was tasked with identifying launch vehicles that are based on large stage diameters (up to the Saturn V S-IC and S-II stage diameters of 33 ft) and utilize high-thrust liquid oxygen (LOX)/RP engines as a First Stage propulsion system. While the trade space for this class of LOX/RP vehicles is relatively large, recent NASA activities (namely the Heavy Lift Launch Vehicle Study in late 2009 and the Heavy Lift Propulsion Technology Study of 2010) examined specific families within this trade space. Although the findings from these studies were incorporated in the Team 2 activity, additional branches of the trade space were examined and alternative approaches to vehicle development were considered. Furthermore, Team 2 set out to define a highly functional, flexible, and cost-effective launch vehicle concept. Utilizing this approach, a versatile two-stage launch vehicle concept was chosen as a preferred option. The preferred vehicle option has the capability to fly in several different configurations (e.g. engine arrangements) that gives this concept an inherent operational flexibility which allows the vehicle to meet a wide range of performance requirements without the need for costly block upgrades. Even still, this concept preserves the option for evolvability should the need arise in future mission scenarios. The foundation of this conceptual design is a focus on low

  19. Large-scale integrated super-computing platform for next generation virtual drug discovery.

    Science.gov (United States)

    Mitchell, Wayne; Matsumoto, Shunji

    2011-08-01

    Traditional drug discovery starts by experimentally screening chemical libraries to find hit compounds that bind to protein targets, modulating their activity. Subsequent rounds of iterative chemical derivitization and rescreening are conducted to enhance the potency, selectivity, and pharmacological properties of hit compounds. Although computational docking of ligands to targets has been used to augment the empirical discovery process, its historical effectiveness has been limited because of the poor correlation of ligand dock scores and experimentally determined binding constants. Recent progress in super-computing, coupled to theoretical insights, allows the calculation of the Gibbs free energy, and therefore accurate binding constants, for usually large ligand-receptor systems. This advance extends the potential of virtual drug discovery. A specific embodiment of the technology, integrating de novo, abstract fragment based drug design, sophisticated molecular simulation, and the ability to calculate thermodynamic binding constants with unprecedented accuracy, are discussed. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. [Sequencing by hybridization methods to generate large arrays of oligonucleotides]. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The subject of this project is to address a pressing need for custom DNA microarrays (chips) which can be easily and at low cost formatted and revised for research. In this sense, the term custom means chips for which there is need for limited quantities (less than hundreds) of any particular chip design which contains a large number of different, users defined sequences. Of the three principal approaches to fabricate DNA microarrays, the two which have been commercialized (a and b below) are not particularly suited to research purposes because of the significant time and costs required, once a result is obtained, to utilize that result in the design of a new and better chip: (a) the photodeprotection scheme used by Affymetrix; and (b) the spotting of pre-synthesized oligos or c-DNA onto surfaces.

  1. Generation of large-bandwidth x-ray free-electron-laser pulses

    Directory of Open Access Journals (Sweden)

    Angela Saa Hernandez

    2016-09-01

    Full Text Available X-ray free-electron lasers (XFELs are modern research tools in disciplines such as biology, material science, chemistry, and physics. Besides the standard operation that aims at minimizing the bandwidth of the produced XFEL radiation, there is a strong scientific demand to produce large-bandwidth XFEL pulses for several applications such as nanocrystallography, stimulated Raman spectroscopy, and multiwavelength anomalous diffraction. We present a self-consistent method that maximizes the XFEL pulse bandwidth by systematically maximizing the energy chirp of the electron beam at the undulator entrance. This is achieved by optimizing the compression scheme and the electron distribution at the source in an iterative back-and-forward tracking. Start-to-end numerical simulations show that a relative bandwidth of 3.25% full-width can be achieved for the hard x-ray pulses in the SwissFEL case.

  2. Properties of Maser-generated Alfvén wave in a Large Laboratory Device

    Science.gov (United States)

    Zhu, Ziyan; Dorfman, Seth; Carter, Troy; Morales, George; Clark, Mary; Rossi, Giovanni

    2016-10-01

    This research is motivated by the investigations of the natural Alfvén wave maser, which refers to the resonant amplification of Alfvén wave in the earth-surrounding plasmas. A resonant cavity that results from applying a locally non-uniform magnetic field to a plasma source region between the anode and cathode of the Large Plasma Device creates the maser. In this research, a lanthanum hexaboride (LaB6)) cathode is used as the plasma source. Above an excitation threshold, selective amplification produces a highly coherent, large amplitude Alfvén wave that propagates out of the resonator through a semitransparent mesh anode into the plasma column where the magnetic field is uniform. The excitation threshold depends on the discharge voltage, and it increases as background magnetic field strength increases; this threshold influences the maser behaviors, including amplitude modulations. The maser with LaB6 source has m = 1 mode and exhibits a right-handed rotation, which is consistent with the electron diamagnetic drift rotation, supporting the possibility of a drift Alfvén wave maser. To distinguish between drift and shear Alfvén waves, a new experiment with the maser cavity excited by a driving circuit was performed. This allows us to access low frequencies (compared to ω*) that cannot be spontaneously driven. The dispersion relation of this driven maser is under investigation. The experimental results will motivate future Alfvén wave study in laboratory devices and thus help better understand space plasma physics such as testing the theory of Alfvén-wave-induced heating of stellar atmosphere. Work supported by the U.S. Department of Energy Office of Science.

  3. Comparison of large central and small decentralized power generation in India

    Energy Technology Data Exchange (ETDEWEB)

    None

    1997-05-01

    This reports evaluates two options for providing reliable power to rural areas in India. The benefits and costs are compared for biomass based distributed generation (DG) systems versus a 1200-MW central grid coal-fired power plant. The biomass based DG systems are examined both as alternatives to grid extension and as supplements to central grid power. The benefits are divided into three categories: those associated with providing reliable power from any source, those associated specifically with biomass based DG technology, and benefits of a central grid coal plant. The report compares the estimated delivered costs of electricity from the DG systems to those of the central plant. The analysis includes estimates for a central grid coal plant and four potential DG system technologies: Stirling engines, direct-fired combustion turbines, fuel cells, and biomass integrated gasification combined cycles. The report also discusses issues affecting India`s rural electricity demand, including economic development, power reliability, and environmental concerns. The results of the costs of electricity comparison between the biomass DG systems and the coal-fired central grid station demonstrated that the DG technologies may be able to produce very competitively priced electricity by the start of the next century. The use of DG technology may provide a practical means of addressing many rural electricity issues that India will face in the future. Biomass DG technologies in particular offer unique advantages for the environment and for economic development that will make them especially attractive. 58 refs., 31 figs.

  4. Control and Protection in Low Voltage Grid with Large Scale Renewable Electricity Generation

    DEFF Research Database (Denmark)

    Mustafa, Ghullam

    of renewable energy based DGs are reduced CO2 emission, reduced operational cost as almost no fuel is used for their operation and less transmission and distribution losses as these units are normally built near to the load centers. This has also resulted in some operational challenges due to the unpredictable...... of the wind speed and solar irradiation fluctuations are tackled. The CIGRE Low Voltage (LV) network comprising two solar PV generating units of 3 kW and 4 kW, one 5.5 kW fixed-pitch fix speed WTG and two battery units each producing energy of 30kwh and 21kwh has been chosen for the study. The study...... the distribution system and the transmission grid has been proposed here. The algorithms, models and methodologies developed during this research study have been tested in a CIGRE low voltage distribution network. The simulation results show that they are able to correctly identify the states of the distribution...

  5. Large-scale monocyte enrichment coupled with a closed culture system for the generation of human dendritic cells.

    Science.gov (United States)

    Pullarkat, Vinod; Lau, Roy; Lee, Sun-Min; Bender, James G; Weber, Jeffrey S

    2002-09-15

    Conventional methods for generating monocyte-derived dendritic cells (DC) for clinical trials utilize the property of plastic adherence to select monocytes from leukapheresis samples. This method is labor-intensive and has the potential for contamination at various steps. We evaluated a large-scale monocyte enrichment procedure using a cell selector (Isolex 300i(R)) followed by culture in a sterile bag system (Stericell(R)) for generation of DC. DC generated in tissue culture flasks after monocyte selection by plastic adherence were compared to those generated in Stericell(R) bags after monocyte enrichment by negative selection with the Isolex(R) 300i. DC were matured with lipopolysaccharide and pulsed with a peptide derived from the melanoma antigen gp100. Peptide-pulsed DC cultured by the two techniques were evaluated for phenotype, viability, ability to induce allogeneic and peptide-specific autologous proliferative responses as well as peptide-specific cytotoxic T-cell responses. The mean monocyte yield from leukapheresis collections was 17+/-2.4%, which increased to 52+/-11% after Isolex(R) selection. The DC yield of plated mononuclear cells from flasks or bags was 2.7+/-0.96% and 4.84+/-2.65%, respectively. DC cultured by both methods expressed high levels of CD86, CD80, CD40, CD83, CD44, CD11c and CD58, and was comparable in their ability to induce allogeneic and peptide-specific autologous proliferative responses as well as gp100 peptide-specific cytotoxic T-cell responses. These results indicate that potent monocyte-derived DC can be generated in a closed culture bag system after monocyte enrichment by immunomagnetic negative selection. Due to the closed nature of the enrichment and culture systems, the potential for contamination is minimized. This protocol is well suited for culturing large numbers of DC for clinical immunotherapy trials.

  6. Wind speed reductions by large-scale wind turbine deployments lower turbine efficiencies and set low generation limits.

    Science.gov (United States)

    Miller, Lee M; Kleidon, Axel

    2016-11-29

    Wind turbines generate electricity by removing kinetic energy from the atmosphere. Large numbers of wind turbines are likely to reduce wind speeds, which lowers estimates of electricity generation from what would be presumed from unaffected conditions. Here, we test how well wind power limits that account for this effect can be estimated without explicitly simulating atmospheric dynamics. We first use simulations with an atmospheric general circulation model (GCM) that explicitly simulates the effects of wind turbines to derive wind power limits (GCM estimate), and compare them to a simple approach derived from the climatological conditions without turbines [vertical kinetic energy (VKE) estimate]. On land, we find strong agreement between the VKE and GCM estimates with respect to electricity generation rates (0.32 and 0.37 We m(-2)) and wind speed reductions by 42 and 44%. Over ocean, the GCM estimate is about twice the VKE estimate (0.59 and 0.29 We m(-2)) and yet with comparable wind speed reductions (50 and 42%). We then show that this bias can be corrected by modifying the downward momentum flux to the surface. Thus, large-scale limits to wind power use can be derived from climatological conditions without explicitly simulating atmospheric dynamics. Consistent with the GCM simulations, the approach estimates that only comparatively few land areas are suitable to generate more than 1 We m(-2) of electricity and that larger deployment scales are likely to reduce the expected electricity generation rate of each turbine. We conclude that these atmospheric effects are relevant for planning the future expansion of wind power.

  7. Ionization of large homogeneous and heterogeneous clusters generated in acetylene-Ar expansions: cluster ion polymerization.

    Science.gov (United States)

    Kočišek, J; Lengyel, J; Fárník, M

    2013-03-28

    Pure acetylene and mixed Ar-acetylene clusters are formed in supersonic expansions of acetylene/argon mixtures and analysed using reflectron time-of-flight mass spectrometer with variable electron energy ionization source. Acetylene clusters composed of more than a hundred acetylene molecules are generated at the acetylene concentration of ≈8%, while mixed species are produced at low concentrations (≈0.7%). The electron energy dependence of the mass spectra revealed the ionization process mechanisms in clusters. The ionization above the threshold for acetylene molecule of 11.5 eV results in the main ionic fragment progression (C2H2)n(+). At the electron energies ≥21.5 eV above the CH+CH(+) dissociative ionization limit of acetylene the fragment ions nominally labelled as (C2H2)nCH(+), n ≥ 2, are observed. For n ≤ 7 these fragments correspond to covalently bound ionic structures as suggested by the observed strong dehydrogenation [(C2H2)n - k × H](+) and [(C2H2)nCH - k × H](+). The dehydrogenation is significantly reduced in the mixed clusters where evaporation of Ar instead of hydrogen can stabilize the nascent molecular ion. The C3H3(+) ion was previously assigned to originate from the benzene molecular ion; however, the low appearance energy of ≈13.7 eV indicates that a less rigid covalently bound structure of C6H6(+) ion must also be formed upon the acetylene cluster electron ionization. The appearance energy of Arn(C2H2)(+) fragments above ≈15.1 eV indicates that the argon ionization is the first step in the fragment ion production, and the appearance energy of Arn≥2(C2H2)m≥2(+) at ≈13.7 eV is discussed in terms of an exciton transfer mechanism.

  8. "Short-term time prediction" of large EQs by the use of "Large Scale Piezoelectricity" generated by the focal areas loaded with excess stress load

    CERN Document Server

    Thanassoulas, C

    2008-01-01

    In this work, it is demonstrated that the Earth's preseismic electric field, which is registered by a pair of electrodes in contact to the ground surface at certain distance from the epicentral area, corresponds to the gradient of the total field generated in the focal area as a function of time and distance from it. The original form of the generated preseismic field follows closely the theoretical piezoelectric potential form. The later is obtained after integration in time of the original registered potential grad data values. Consequently, the time of occurrence of the imminent earthquake (collapsing of the rock formation) is estimated by the classical laws of rock fracturing based on theoretical Rock Mechanics. The methodology has been tested on the grad potential data, registered in Greece, before four large EQs which took place in the regional area as follows: Izmit, Turkey EQ (M = 7.8R, 17th August, 1999), Milos, Greece EQ (M = 5.6R, 21st May, 2002), Kythira Greece EQ (M = 6.9R, 8th January, 2006) and...

  9. Prospective large-scale field study generates predictive model identifying major contributors to colony losses.

    Directory of Open Access Journals (Sweden)

    Merav Gleit Kielmanowicz

    2015-04-01

    Full Text Available Over the last decade, unusually high losses of colonies have been reported by beekeepers across the USA. Multiple factors such as Varroa destructor, bee viruses, Nosema ceranae, weather, beekeeping practices, nutrition, and pesticides have been shown to contribute to colony losses. Here we describe a large-scale controlled trial, in which different bee pathogens, bee population, and weather conditions across winter were monitored at three locations across the USA. In order to minimize influence of various known contributing factors and their interaction, the hives in the study were not treated with antibiotics or miticides. Additionally, the hives were kept at one location and were not exposed to potential stress factors associated with migration. Our results show that a linear association between load of viruses (DWV or IAPV in Varroa and bees is present at high Varroa infestation levels (>3 mites per 100 bees. The collection of comprehensive data allowed us to draw a predictive model of colony losses and to show that Varroa destructor, along with bee viruses, mainly DWV replication, contributes to approximately 70% of colony losses. This correlation further supports the claim that insufficient control of the virus-vectoring Varroa mite would result in increased hive loss. The predictive model also indicates that a single factor may not be sufficient to trigger colony losses, whereas a combination of stressors appears to impact hive health.

  10. Large Hadron Collider at CERN: Beams Generating High-Energy-Density Matter

    CERN Document Server

    Tahir, N A; Shutov, A; Lomonosov, IV; Piriz, A R; Hoffmann, D H H; Deutsch, C; Fortov, V E

    2009-01-01

    This paper presents numerical simulations that have been carried out to study the thermodynamic and hydrodynamic response of a solid copper cylindrical target that is facially irradiated along the axis by one of the two Large Hadron Collider (LHC) 7 TeV/c proton beams. The energy deposition by protons in solid copper has been calculated using an established particle interaction and Monte Carlo code, FLUKA, which is capable of simulating all components of the particle cascades in matter, up to multi-TeV energies. This data has been used as input to a sophisticated two--dimensional hydrodynamic computer code, BIG2 that has been employed to study this problem. The prime purpose of these investigations was to assess the damage caused to the equipment if the entire LHC beam is lost at a single place. The FLUKA calculations show that the energy of protons will be deposited in solid copper within about 1~m assuming constant material parameters. Nevertheless, our hydrodynamic simulations have shown that the energy de...

  11. A general method to modify BACs to generate large recombinant DNA fragments.

    Science.gov (United States)

    Shen, Wei; Huang, Yue; Tang, Yi; Liu, De-Pei; Liang, Chih-Chuan

    2005-11-01

    Bacterial artificial chromosome (BAC) has the capacity to clone DNA fragments in excess of 300 kb. It also has the considerable advantages of stable propagation and ease of purification. These features make BAC suitable in genetic research, such as library construction, transgenic mice production, and gene targeting constructs. Homologous recombination in Escherichia coli, a process named recombineering, has made the modification of BACs easy and reliable. We report here a modified recombineering method that can efficiently mediate the fusion of large DNA fragments from two or more different BACs. With the introduction of kanamycin-resistant gene and proposed rare-cutting restriction endonuclease (RCRE) sites into two BACs, a 82.6-kb DNA fragment containing the inverted human alpha-globin genes (theta, alpha1, alpha2, and zeta) from BAC191K2 and the locus control region (LCR) of human beta-globin gene locus (from the BAC186D7) was reconstructed. This approach for combining different BAC DNA fragments should facilitate many kinds of genomic experiments.

  12. Peculiar Velocities into the Next Generation: Cosmological Parameters From Large Surveys without Bias from Nonlinear Structure

    CERN Document Server

    Abate, Alexandra; Teodoro, Luis F A; Warren, Michael S; Hendry, Martin

    2008-01-01

    We investigate methods to best estimate the normalisation of the mass density fluctuation power spectrum (sigma_8) using peculiar velocity data from a survey like the Six degree Field Galaxy Velocity Survey (6dFGSv). We focus on two potential problems (i) biases from nonlinear growth of structure and (ii) the large number of velocities in the survey. Simulations of LambdaCDM-like models are used to test the methods. We calculate the likelihood from a full covariance matrix of velocities averaged in grid cells. This simultaneously reduces the number of data points and smooths out nonlinearities which tend to dominate on small scales. We show how the averaging can be taken into account in the predictions in a practical way, and show the effect of the choice of cell size. We find that a cell size can be chosen that significantly reduces the nonlinearities without significantly increasing the error bars on cosmological parameters. We compare our results with those from a principal components analysis following Wa...

  13. Generation of an attenuated Tiantan vaccinia virus by deletion of the ribonucleotide reductase large subunit.

    Science.gov (United States)

    Kan, Shifu; Jia, Peng; Sun, Lili; Hu, Ningning; Li, Chang; Lu, Huijun; Tian, Mingyao; Qi, Yanxin; Jin, Ningyi; Li, Xiao

    2014-09-01

    Attenuation of the virulence of vaccinia Tiantan virus (VTT) underlies the strategy adopted for mass vaccination campaigns. This strategy provides advantages of safety and efficacy over traditional vaccines and is aimed at minimization of adverse health effects. In this study, a mutant form of the virus, MVTT was derived from VTT by deletion of the ribonucleotide reductase large subunit (R1) (TI4L). Compared to wild-type parental (VTT) and revertant (VTT-rev) viruses, virulence of the mutant MVTT was reduced by 100-fold based on body weight reduction and by 3,200-fold based on determination of the intracranial 50% lethal infectious dose. However, the immunogenicity of MVTT was equivalent to that of the parental VTT. We also demonstrated that the TI4L gene is not required for efficient replication. These data support the conclusion that MVTT can be used as a replicating virus vector or as a platform for the development of vaccines against infectious diseases and for cancer therapy.

  14. Prospective large-scale field study generates predictive model identifying major contributors to colony losses.

    Science.gov (United States)

    Kielmanowicz, Merav Gleit; Inberg, Alex; Lerner, Inbar Maayan; Golani, Yael; Brown, Nicholas; Turner, Catherine Louise; Hayes, Gerald J R; Ballam, Joan M

    2015-04-01

    Over the last decade, unusually high losses of colonies have been reported by beekeepers across the USA. Multiple factors such as Varroa destructor, bee viruses, Nosema ceranae, weather, beekeeping practices, nutrition, and pesticides have been shown to contribute to colony losses. Here we describe a large-scale controlled trial, in which different bee pathogens, bee population, and weather conditions across winter were monitored at three locations across the USA. In order to minimize influence of various known contributing factors and their interaction, the hives in the study were not treated with antibiotics or miticides. Additionally, the hives were kept at one location and were not exposed to potential stress factors associated with migration. Our results show that a linear association between load of viruses (DWV or IAPV) in Varroa and bees is present at high Varroa infestation levels (>3 mites per 100 bees). The collection of comprehensive data allowed us to draw a predictive model of colony losses and to show that Varroa destructor, along with bee viruses, mainly DWV replication, contributes to approximately 70% of colony losses. This correlation further supports the claim that insufficient control of the virus-vectoring Varroa mite would result in increased hive loss. The predictive model also indicates that a single factor may not be sufficient to trigger colony losses, whereas a combination of stressors appears to impact hive health.

  15. Generations.

    Science.gov (United States)

    Chambers, David W

    2005-01-01

    Groups naturally promote their strengths and prefer values and rules that give them an identity and an advantage. This shows up as generational tensions across cohorts who share common experiences, including common elders. Dramatic cultural events in America since 1925 can help create an understanding of the differing value structures of the Silents, the Boomers, Gen Xers, and the Millennials. Differences in how these generations see motivation and values, fundamental reality, relations with others, and work are presented, as are some applications of these differences to the dental profession.

  16. Differential Protection for an Outgoing Transformer of Large-Scale Doubly Fed Induction Generator-Based Wind Farms

    Directory of Open Access Journals (Sweden)

    Bingtuan Gao

    2014-08-01

    Full Text Available With the rapid development of wind energy, relay protection for large-scale wind farms has been attracting some researchers, due to the absence of standards. Based on the large-scale doubly fed induction generator (DFIG-based wind farms located in Gansu Province, China, this paper studies the differential protection for the outgoing power transformer of large-scale DFIG-based wind farms. According to the equivalent circuit of the power grid integrated with wind farms, the main frequency components of current and voltage during faults are identified mathematically and then verified by simulations. The results show that the frequencies of current and voltage at the terminals of outgoing transmission lines are inconsistent. Following the feature of frequency inconsistency, the adaptability of differential protection is analyzed, and it is found that differential protection for an outgoing transformer in large-scale wind farms may fail once ignoring the frequency inconsistency. Simulation studies demonstrate that inconsistent frequency characteristics will deteriorate the sensitivity and reliability of differential protection. Finally, several suggestions are provided for improving the performance of relay protections for large-scale DFIG-based wind farms.

  17. Large-scale road safety programmes in low- and middle-income countries: an opportunity to generate evidence.

    Science.gov (United States)

    Hyder, Adnan A; Allen, Katharine A; Peters, David H; Chandran, Aruna; Bishai, David

    2013-01-01

    The growing burden of road traffic injuries, which kill over 1.2 million people yearly, falls mostly on low- and middle-income countries (LMICs). Despite this, evidence generation on the effectiveness of road safety interventions in LMIC settings remains scarce. This paper explores a scientific approach for evaluating road safety programmes in LMICs and introduces such a road safety multi-country initiative, the Road Safety in 10 Countries Project (RS-10). By building on existing evaluation frameworks, we develop a scientific approach for evaluating large-scale road safety programmes in LMIC settings. This also draws on '13 lessons' of large-scale programme evaluation: defining the evaluation scope; selecting study sites; maintaining objectivity; developing an impact model; utilising multiple data sources; using multiple analytic techniques; maximising external validity; ensuring an appropriate time frame; the importance of flexibility and a stepwise approach; continuous monitoring; providing feedback to implementers, policy-makers; promoting the uptake of evaluation results; and understanding evaluation costs. The use of relatively new approaches for evaluation of real-world programmes allows for the production of relevant knowledge. The RS-10 project affords an important opportunity to scientifically test these approaches for a real-world, large-scale road safety evaluation and generate new knowledge for the field of road safety.

  18. Diagnosis of Short-Circuit Fault in Large-Scale Permanent-Magnet Wind Power Generator Based on CMAC

    Directory of Open Access Journals (Sweden)

    Chin-Tsung Hsieh

    2013-01-01

    Full Text Available This study proposes a method based on the cerebellar model arithmetic controller (CMAC for fault diagnosis of large-scale permanent-magnet wind power generators and compares the results with Error Back Propagation (EBP. The diagnosis is based on the short-circuit faults in permanent-magnet wind power generators, magnetic field change, and temperature change. Since CMAC is characterized by inductive ability, associative ability, quick response, and similar input signals exciting similar memories, it has an excellent effect as an intelligent fault diagnosis implement. The experimental results suggest that faults can be diagnosed effectively after only training CMAC 10 times. In comparison to training 151 times for EBP, CMAC is better than EBP in terms of training speed.

  19. Combined electrochemical, heat generation, and thermal model for large prismatic lithium-ion batteries in real-time applications

    Science.gov (United States)

    Farag, Mohammed; Sweity, Haitham; Fleckenstein, Matthias; Habibi, Saeid

    2017-08-01

    Real-time prediction of the battery's core temperature and terminal voltage is very crucial for an accurate battery management system. In this paper, a combined electrochemical, heat generation, and thermal model is developed for large prismatic cells. The proposed model consists of three sub-models, an electrochemical model, heat generation model, and thermal model which are coupled together in an iterative fashion through physicochemical temperature dependent parameters. The proposed parameterization cycles identify the sub-models' parameters separately by exciting the battery under isothermal and non-isothermal operating conditions. The proposed combined model structure shows accurate terminal voltage and core temperature prediction at various operating conditions while maintaining a simple mathematical structure, making it ideal for real-time BMS applications. Finally, the model is validated against both isothermal and non-isothermal drive cycles, covering a broad range of C-rates, and temperature ranges [-25 °C to 45 °C].

  20. Addressable, large-field second harmonic generation microscopy based on 2D acousto-optical deflector and spatial light modulator.

    Science.gov (United States)

    Shao, Yonghong; Liu, Honghai; Qin, Wan; Qu, Junle; Peng, Xiang; Niu, Hanben; Gao, Bruce Z

    2012-09-01

    We present an addressable, large-field second harmonic generation microscope by combining a 2D acousto-optical deflector with a spatial light modulator. The SLM shapes an incoming mode-locked, near-infrared Ti:Sapphire laser beam into a multifocus array, which can be rapidly scanned by changing the incident angle of the laser beam using a 2D acousto-optical deflector. Compared to the single-beam-scan technique, the multifocus array scan can increase the scanning rate and the field-of-view size with the multi-region imaging ability.

  1. Literature Review on Reasons and Countermeasures on Large-scale Off-grid of Wind Turbine Generator System

    Directory of Open Access Journals (Sweden)

    Zhu Jun

    2015-01-01

    Full Text Available This paper reviews the present situation of the application of wind turbines generator system(WTGS at home and abroad, describes the strategic significance and the value of sustainable development of the wind power in the country, illustrates the problems, a variety of reasons and responses on large-scale off-grid of WTGS, compares the advantages and disadvantages of various methods, gives full consideration to the actual demand for WTGS works and characteristics and points out the further research.

  2. Generating functional and large N limit of nonlocal 2D generalized Yang-Mills theories (nlgYM 2's)

    Science.gov (United States)

    Saaidi, K.; Sajadi, H. M.

    2001-01-01

    Using the path integral method, we calculate the partition function and the generating functional (of the field strengths) on nonlocal generalized 2D Yang Mills theories (nlgYM_2's), which are nonlocal in the auxiliary field. This has been considered before by Saaidi and Khorrami. Our calculations are done for general surfaces. We find a general expression for the free energy of W(φ) =φ^{2k} in nlgYM_2 theories at the strong coupling phase (SCP) regime (A > A_c) for large groups. In the specific φ^4 model, we show that the theory has a third order phase transition.

  3. Generation of large fifth-order nonlinear phase shifts by use of lossless χ(2) cascaded nonlinear processes

    Institute of Scientific and Technical Information of China (English)

    XU Guang; QIAN Liejia; WANG Tao; FAN Dianyuan; LI Fuming

    2004-01-01

    It is shown that the cascaded fifth-order nonlinear phase shifts will increase with energy loss in the cascaded processes. Essentially different from the multi-photon absorption accompanied with inherent material nonlinearities, the loss of fundamental wave in a cascaded process is controllable and suppressible. By introducing difference frequencies generated from the reaction between the fundamental and its second harmonic after the cascaded processes, the fundamental wave can be free of energy loss, while the large cascaded fifth-order nonlinear phase shift is maintained.

  4. Generation of large-scale vortex dislocations in a three- dimensional wake-type flow

    Institute of Scientific and Technical Information of China (English)

    LING; Guocan

    2001-01-01

    ., Eckelmann, H., Vortex splitting and its consequences in the vortex street wake of cylinders at low Reynolds number, Phys. Fluids, 1989, 1: 189.[15]Gerrard, J. H., The three-dimensional structure of the wake of a circular cylinder, J. Fluid Mech., 1996, 25: 143.[16]Gaster, M., Vortex shedding from circular cylinder at low Reynolds number, J. Fluid Mech., 1971, 46: 749.[17]Bearman, P. W., Challenging problems in bluff body wakes, bluff-body wakes, dynamics and instabilities, IUTAM Symposium Gittingen/Germany, 1992, 19.[18]So, A., Maekawa, H., Study of vortex dislocations in the wake of a flat plate with finite thickness, Transactions of the Japan Society of Mechanical Engineers B, 2000, 66: 649.[19]Browand, F. K., Troutt, T. R., The turbulent mixing layer: geometry of large vortices, J. Fluid Mech., 1985, 158: 489.[20]Ling Guocan, Xiong Zhongmin, The three dimensional flow features of interaction between two vortex streets, in Proceedings of the Eighth International Offshore and Polar Engineering Conference, Montréal, Canada, May 24—29, 1998.[21]Pocheau, A., Croquette, V., Gal, P. L., Turbulence in a cylindrical container of Argon near threshold of convection, Phys. Rev. Lett., 1985, 55: 1094.[22]Noack, B. R., Ohle, F., Eckelmann, H., On the cell formation in vortex streets, J. Fluid Mech., 1991, 227: 293.[23]Albarède, R., Provansal, M., Quasi-periodic cylinder wakes and the Ginzburg-Landau model. J. Fluid Mech., 1995, 291: 191.[24]Park, D. S., Redekopp, L. G., Selection principles for spatio-temporal patterns in wake flows, in Proc. IUTAM Symp. on Bluff-body Wake, Dynamics, and Instability, Gittingen, Sept. 7—11, 1992.[25]Monkewitz, P. A., Williamson, C. H. K., Miller, G. D., Phase dynamics of K-rm-n vortices in cylinder wakes, Phys. Fluids, A, 1996, 8: 91.[26]Triantafyllou, G. S., Karniadakis, G. E., Computational reducibility of unsteady viscous flows, Phys. Fluids A, 1990, 2: 653.[27]Xiong, Z. M., Ling, G. C

  5. A third-generation density-functional-theory-based method for calculating canonical molecular orbitals of large molecules.

    Science.gov (United States)

    Hirano, Toshiyuki; Sato, Fumitoshi

    2014-07-28

    We used grid-free modified Cholesky decomposition (CD) to develop a density-functional-theory (DFT)-based method for calculating the canonical molecular orbitals (CMOs) of large molecules. Our method can be used to calculate standard CMOs, analytically compute exchange-correlation terms, and maximise the capacity of next-generation supercomputers. Cholesky vectors were first analytically downscaled using low-rank pivoted CD and CD with adaptive metric (CDAM). The obtained Cholesky vectors were distributed and stored on each computer node in a parallel computer, and the Coulomb, Fock exchange, and pure exchange-correlation terms were calculated by multiplying the Cholesky vectors without evaluating molecular integrals in self-consistent field iterations. Our method enables DFT and massively distributed memory parallel computers to be used in order to very efficiently calculate the CMOs of large molecules.

  6. Wind power integration into the automatic generation control of power systems with large-scale wind power

    Directory of Open Access Journals (Sweden)

    Abdul Basit

    2014-10-01

    Full Text Available Transmission system operators have an increased interest in the active participation of wind power plants (WPP in the power balance control of power systems with large wind power penetration. The emphasis in this study is on the integration of WPPs into the automatic generation control (AGC of the power system. The present paper proposes a coordinated control strategy for the AGC between combined heat and power plants (CHPs and WPPs to enhance the security and the reliability of a power system operation in the case of a large wind power penetration. The proposed strategy, described and exemplified for the future Danish power system, takes the hour-ahead regulating power plan for generation and power exchange with neighbouring power systems into account. The performance of the proposed strategy for coordinated secondary control is assessed and discussed by means of simulations for different possible future scenarios, when wind power production in the power system is high and conventional production from CHPs is at a minimum level. The investigation results of the proposed control strategy have shown that the WPPs can actively help the AGC, and reduce the real-time power imbalance in the power system, by down regulating their production when CHPs are unable to provide the required response.

  7. Hot electron generation under large-signal radio frequency operation of GaN high-electron-mobility transistors

    Science.gov (United States)

    Latorre-Rey, Alvaro D.; Sabatti, Flavio F. M.; Albrecht, John D.; Saraniti, Marco

    2017-07-01

    In order to assess the underlying physical mechanisms of hot carrier-related degradation such as defect generation in millimeter-wave GaN power amplifiers, we have simulated the electron energy distribution function under large-signal radio frequency conditions in AlGaN/GaN high-electron-mobility transistors. Our results are obtained through a full band Monte Carlo particle-based simulator self-consistently coupled to a harmonic balance circuit solver. At lower frequency, simulations of a Class AB power amplifier at 10 GHz show that the peak hot electron generation is up to 43% lower under RF drive than it is under DC conditions, regardless of the input power or temperature of operation. However, at millimeter-wave operation up to 40 GHz, RF hot carrier generation reaches that from DC biasing and even exceeds it up to 75% as the amplifier is driven into compression. Increasing the temperature of operation also shows that degradation of DC and RF characteristics are tightly correlated and mainly caused by increased phonon scattering. The accurate determination of the electron energy mapping is demonstrated to be a powerful tool for the extraction of compact models used in lifetime and reliability analysis.

  8. A Large Generation Gap Must be Taken into Account in the Consideration of the Effects of Music Therapy in Japan

    Directory of Open Access Journals (Sweden)

    Kenichi Matunami

    2011-11-01

    Full Text Available We studied the effects of music upon human emotion with ESA-16, a special computer soft ware program for the analysis of human emotion from EEG. Subjects were 6 old and 8 healthy adult person. Four songs were selected as test music, all of which are very familiar to the old. Their titles were "Furusato", "Akogareno Hawaii-kouro", "Saitarou-busi" and "Kagewositaite". They were chosen because we used them very often in our recipe (repertoire of music therapy for old person. ESA-16 enabled us to analyze EEG into four components of emotion; Anger/Stress, Joy, Sadness and Relaxation in a pseudo-real time manner. The experiments with ESA-16 revealed that the old person showed a significant decrease in Anger/Stress and an increase in Joy during listening to "Furusato", and a decrease in Sadness and an increase in Relaxation while listening to "Saitarou-busi" with significance. On the other hand, no significant emotional changes were observed in the adult subjects while listening to all four music. For the explanation of these facts, we offered a proposition that the difference in emotional changes observed while listening to four test songs was produced by a large generation gap lying between the old and the adult. This generation gap was produced by the drastic cultural and educational changes since the occupation by the USA, after the unconditional surrender of Japan to the Allied Forces in 1945. This year marks the critical demarcation in producing the large generation gap in Japan. From this time on, the adult are educated under the new democratic system, while the old remained completely in the past as the remains of absolutism and feudalism.

  9. The Renormalization Group and Its Applications to Generating Coarse-Grained Models of Large Biological Molecular Systems.

    Science.gov (United States)

    Koehl, Patrice; Poitevin, Frédéric; Navaza, Rafael; Delarue, Marc

    2017-03-14

    Understanding the dynamics of biomolecules is the key to understanding their biological activities. Computational methods ranging from all-atom molecular dynamics simulations to coarse-grained normal-mode analyses based on simplified elastic networks provide a general framework to studying these dynamics. Despite recent successes in studying very large systems with up to a 100,000,000 atoms, those methods are currently limited to studying small- to medium-sized molecular systems due to computational limitations. One solution to circumvent these limitations is to reduce the size of the system under study. In this paper, we argue that coarse-graining, the standard approach to such size reduction, must define a hierarchy of models of decreasing sizes that are consistent with each other, i.e., that each model contains the information of the dynamics of its predecessor. We propose a new method, Decimate, for generating such a hierarchy within the context of elastic networks for normal-mode analysis. This method is based on the concept of the renormalization group developed in statistical physics. We highlight the details of its implementation, with a special focus on its scalability to large systems of up to millions of atoms. We illustrate its application on two large systems, the capsid of a virus and the ribosome translation complex. We show that highly decimated representations of those systems, containing down to 1% of their original number of atoms, still capture qualitatively and quantitatively their dynamics. Decimate is available as an OpenSource resource.

  10. A study to solve the variability of wind generation through integration of large-scale hydraulic generation; Um estudo para resolver a variabilidade da geracao eolica atraves da integracao em larga escala com geracao hidraulica

    Energy Technology Data Exchange (ETDEWEB)

    Emmerik, Emanuel Leonardus van; Steinberger, Johann Michael; Aredes, Mauricio [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEE/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Eletrica

    2010-07-01

    The optimal deployment of wind generation with the hydro generation is being investigated as a viable option to assist in resolving the constraints coming ahead as a consequence of the tendency of recovery in the Brazilian Amazon basin for expansion of generating facilities. It is in the validity of this research that this work is focused. The value is shown of feasibility studies of using water power generation to offset the variability of wind generation when it is deployed on a large scale. Preliminary results are presented for the variability of wind generation at various cycles, the variability of the availability of hydropower. (author)

  11. Generation of large-scale magnetic fields, non-Gaussianity, and primordial gravitational waves in inflationary cosmology

    CERN Document Server

    Bamba, Kazuharu

    2014-01-01

    The generation of large-scale magnetic fields in inflationary cosmology is explored, in particular, in a kind of moduli inflation motivated by racetrack inflation in the context of the Type IIB string theory. In this model, the conformal invariance of the hypercharge electromagnetic fields is broken thanks to the coupling of both the scalar and pseudoscalar fields to the hypercharge electromagnetic fields. The following three cosmological observable quantities are first evaluated: The current magnetic field strength on the Hubble horizon scale, which is much smaller than the upper limit from the back reaction problem, the local non-Gaussianity of the curvature perturbations due to the existence of the massive gauge fields, and the tensor-to-scalar ratio. It is explicitly demonstrated that the resultant values of the local non-Gaussianity and the tensor-to-scalar ratio are consistent with the Planck data.

  12. Motivation and challenge to capture both large-scale and local transport in next generation accretion theory

    DEFF Research Database (Denmark)

    Blackman, Eric G.; Nauman, Farrukh

    2015-01-01

    > Accretion disc theory is less developed than stellar evolution theory although a similarly mature phenomenological picture is ultimately desired. While the interplay of theory and numerical simulations has amplified community awareness of the role of magnetic fields in angular momentum transport...... theory, and one which does not include large-scale transport. Observations of coronae and jets, combined with the interpretation of results from shearing box simulations, of the magnetorotational instability (MRI) suggest that a significant fraction of disc transport is indeed non-local. We show...... attention toward local simulations, but the next generation of global simulations should help to inform improved mean field theories. Mean field accretion theory and mean field dynamo theory should in fact be unified into a single theory that predicts the time evolution of spectra and luminosity from...

  13. Jaw-muscle fiber architecture in tufted capuchins favors generating relatively large muscle forces without compromising jaw gape.

    Science.gov (United States)

    Taylor, Andrea B; Vinyard, Christopher J

    2009-12-01

    Tufted capuchins (sensu lato) are renowned for their dietary flexibility and capacity to exploit hard and tough objects. Cebus apella differs from other capuchins in displaying a suite of craniodental features that have been functionally and adaptively linked to their feeding behavior, particularly the generation and dissipation of relatively large jaw forces. We compared fiber architecture of the masseter and temporalis muscles between C. apella (n=12) and two "untufted" capuchins (C. capucinus, n=3; C. albifrons, n=5). These three species share broadly similar diets, but tufted capuchins occasionally exploit mechanically challenging tissues. We tested the hypothesis that tufted capuchins exhibit architectural properties of their jaw muscles that facilitate relatively large forces including relatively greater physiologic cross-sectional areas (PCSA), more pinnate fibers, and lower ratios of mass to tetanic tension (Mass/P(0)). Results show some evidence supporting these predictions, as C. apella has relatively greater superficial masseter and temporalis PCSAs, significantly so only for the temporalis following Bonferroni adjustment. Capuchins did not differ in pinnation angle or Mass/P(0). As an architectural trade-off between maximizing muscle force and muscle excursion/contraction velocity, we also tested the hypothesis that C. apella exhibits relatively shorter muscle fibers. Contrary to our prediction, there are no significant differences in relative fiber lengths between tufted and untufted capuchins. Therefore, we attribute the relatively greater PCSAs in tufted capuchins primarily to their larger muscle masses. These findings suggest that relatively large jaw-muscle PCSAs can be added to the suite of masticatory features that have been functionally linked to the exploitation of a more resistant diet by C. apella. By enlarging jaw-muscle mass to increase PCSA, rather than reducing fiber lengths and increasing pinnation, tufted capuchins appear to have

  14. ZERO MODE NATURAL FREQUENCY AND NONLINEAR VIBRATION OF COUPLED LATERAL AND TORSION OF A LARGE TURBINE GENERATOR

    Institute of Scientific and Technical Information of China (English)

    Ta Na; Qiu Jiajun; Cai Ganhua

    2005-01-01

    Zero mode natural frequency (ZMNF) is found during experiments. The ZMNF and vibrations resulted by it are studied. First, calculating method of the ZMNF excited by electromagnetic in vibrational system of coupled mechanics and electrics are given from the view of magnetic energy.Laws that the ZMNF varies with active power and exciting current are obtained and are verified by experiments. Then, coupled lateral and torsional vibration of rotor shaft system is studied by considering rest eccentricity, rotating eccentricity and swing eccentricity. Using Largrange-Maxwell equation when three phases are asymmetric derives differential equation of the coupled vibration. With energy method of nonlinear vibration, amplitude-frequency characteristics of resonance are studied when rotating speed of rotor equals to ZMNF. The results show that ZMNF will occur in turbine generators by the action of electromagnetic. Because ZMNF varies with electromagnetic parameters,resonance can occur when exciting frequency of the rotor speed is fixed whereas exciting current change. And also find that a generator is in the state of large amplitude in rated exciting current.

  15. Methods to isolate a large amount of generative cells, sperm cells and vegetative nuclei from tomato pollen for omics analysis

    Directory of Open Access Journals (Sweden)

    Yunlong eLu

    2015-06-01

    Full Text Available The development of sperm cells from microspores involves a set of finely regulated molecular and cellular events and the coordination of these events. The mechanisms underlying these events and their interconnections remain a major challenge. Systems analysis of genome-wide molecular networks and functional modules with high-throughput omics approaches is crucial for understanding the mechanisms; however, this study is hindered because of the difficulty in isolating a large amount of cells of different types, especially generative cells (GCs, from the pollen. Here, we optimized the conditions of tomato pollen germination and pollen tube growth to allow for long-term growth of pollen tubes in vitro with sperm cells (SCs generated in the tube. Using this culture system, we developed methods for isolating GCs, SCs and vegetative-cell nuclei (VN from just-germinated tomato pollen grains and growing pollen tubes and their purification by Percoll density gradient centrifugation. The purity and viability of isolated GCs and SCs were confirmed by microscopy examination and fluorescein diacetate staining, respectively, and the integrity of VN was confirmed by propidium iodide staining. We could obtain about 1.5 million GCs and 2.0 million SCs each from 180 mg initiated pollen grains, and 10 million VN from 270 mg initiated pollen grains germinated in vitro in each experiment. These methods provide the necessary preconditions for systematic biology studies of SC development and differentiation in higher plants.

  16. Large scale production of vesicles by hollow fiber extrusion: a novel method for generating polymersome encapsulated hemoglobin dispersions.

    Science.gov (United States)

    Rameez, Shahid; Bamba, Ibrahim; Palmer, Andre F

    2010-04-06

    Vesicles, which include both liposomes and polymersomes (polymer vesicles), are being developed as therapeutic drug carriers. In this study, we present a fully scalable low pressure extrusion methodology for preparing vesicles. Vesicles were generated by continuous extrusion through a 200 nm pore diameter hollow fiber (HF) membrane. The first half of this study describes a method for generating empty polymersomes composed of different molecular weight amphiphilic poly(butadiene-b-ethylene oxide) (PBD-b-PEO) diblock copolymers on a large scale (50-100 mL) using a HF membrane. Monodisperse empty polymersomes were formed with particle diameters slightly less than 200 nm, which were close to the rated 200 nm pore size of the HF membrane. The second half of this study describes the successful encapsulation of hemoglobin (Hb) inside the aqueous core of polymersomes using the HF extrusion methodology. We demonstrate that polymersome encapsulated hemoglobin (PEH) particles formed by this technique had similar oxygen affinity, cooperativity coefficient, and methemoglobin (metHb) level compared to PEH particles formed by the 1 mL volume small scale manual extrusion method. Most notably, Hb encapsulation inside the polymer vesicles formed by the HF extrusion method increased 2-fold compared to the manual extrusion method. This work is important, since it will enable facile scale-up of homogeneous vesicle dispersions that are typically required for preclinical and clinical studies as well as industrial use.

  17. Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model.

    Science.gov (United States)

    Tatara, Alexander M; Kretlow, James D; Spicer, Patrick P; Lu, Steven; Lam, Johnny; Liu, Wei; Cao, Yilin; Liu, Guangpeng; Jackson, John D; Yoo, James J; Atala, Anthony; van den Beucken, Jeroen J J P; Jansen, John A; Kasper, F Kurtis; Ho, Tang; Demian, Nagi; Miller, Michael John; Wong, Mark E; Mikos, Antonios G

    2015-05-01

    The reconstruction of large craniofacial defects remains a significant clinical challenge. The complex geometry of facial bone and the lack of suitable donor tissue often hinders successful repair. One strategy to address both of these difficulties is the development of an in vivo bioreactor, where a tissue flap of suitable geometry can be orthotopically grown within the same patient requiring reconstruction. Our group has previously designed such an approach using tissue chambers filled with morcellized bone autograft as a scaffold to autologously generate tissue with a predefined geometry. However, this approach still required donor tissue for filling the tissue chamber. With the recent advances in biodegradable synthetic bone graft materials, it may be possible to minimize this donor tissue by replacing it with synthetic ceramic particles. In addition, these flaps have not previously been transferred to a mandibular defect. In this study, we demonstrate the feasibility of transferring an autologously generated tissue-engineered vascularized bone flap to a mandibular defect in an ovine model, using either morcellized autograft or synthetic bone graft as scaffold material.

  18. Large scale single nucleotide polymorphism discovery in unsequenced genomes using second generation high throughput sequencing technology: applied to turkey

    Directory of Open Access Journals (Sweden)

    den Dunnen Johan T

    2009-10-01

    Full Text Available Abstract Background The development of second generation sequencing methods has enabled large scale DNA variation studies at moderate cost. For the high throughput discovery of single nucleotide polymorphisms (SNPs in species lacking a sequenced reference genome, we set-up an analysis pipeline based on a short read de novo sequence assembler and a program designed to identify variation within short reads. To illustrate the potential of this technique, we present the results obtained with a randomly sheared, enzymatically generated, 2-3 kbp genome fraction of six pooled Meleagris gallopavo (turkey individuals. Results A total of 100 million 36 bp reads were generated, representing approximately 5-6% (~62 Mbp of the turkey genome, with an estimated sequence depth of 58. Reads consisting of bases called with less than 1% error probability were selected and assembled into contigs. Subsequently, high throughput discovery of nucleotide variation was performed using sequences with more than 90% reliability by using the assembled contigs that were 50 bp or longer as the reference sequence. We identified more than 7,500 SNPs with a high probability of representing true nucleotide variation in turkeys. Increasing the reference genome by adding publicly available turkey BAC-end sequences increased the number of SNPs to over 11,000. A comparison with the sequenced chicken genome indicated that the assembled turkey contigs were distributed uniformly across the turkey genome. Genotyping of a representative sample of 340 SNPs resulted in a SNP conversion rate of 95%. The correlation of the minor allele count (MAC and observed minor allele frequency (MAF for the validated SNPs was 0.69. Conclusion We provide an efficient and cost-effective approach for the identification of thousands of high quality SNPs in species currently lacking a sequenced genome and applied this to turkey. The methodology addresses a random fraction of the genome, resulting in an even

  19. VIENTOS: a feasibility study of innovative pupil systems for the new generation of instruments in the large telescopes

    Science.gov (United States)

    García-Vargas, M. L.; Pérez-Calpena, A.; Gallego, J.; Gil de Paz, A.; Sánchez-Blanco, E.; Martínez-Delgado, I.; Maldonado Medina, M.; Zamorano Calvo, J.

    2012-09-01

    The goal of VIENTOS project is to analyze pupil innovative systems that could be used in the new generation of instruments for the large telescopes. This study tries to identify the current scientific needs, to understand why some of them have not been fulfilled yet (due to pre-conceived technical ideas or to managerial reasons) and to propose optomechanical solutions for these pupil elements that could produce a qualitative leap in the performance of the instruments to operate in the large telescopes. VIENTOS is currently on-going as a collaborative project between FRACTAL and the University Complutense of Madrid (UCM) and is being partially funded by a CDTI grant under the program Industry for Science. CDTI is the Development and Industrial Transfer Center from the Minister of Science and Innovation (Spain). Among the different innovative systems that we have carried out, our team has explored potential solutions for narrow band Imaging with tunable filters in the near-IR and a novel pupil system called sliced-pupil grating, a device designed for increasing the spectral resolution in astronomical spectrographs, without changing the geometry of the main optics. Nanotechnology customized filters to be applicable to astronomical systems are under study.

  20. The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity.

    Science.gov (United States)

    Dapprich, Johannes; Ferriola, Deborah; Mackiewicz, Kate; Clark, Peter M; Rappaport, Eric; D'Arcy, Monica; Sasson, Ariella; Gai, Xiaowu; Schug, Jonathan; Kaestner, Klaus H; Monos, Dimitri

    2016-07-09

    The ability to capture and sequence large contiguous DNA fragments represents a significant advancement towards the comprehensive characterization of complex genomic regions. While emerging sequencing platforms are capable of producing several kilobases-long reads, the fragment sizes generated by current DNA target enrichment technologies remain a limiting factor, producing DNA fragments generally shorter than 1 kbp. The DNA enrichment methodology described herein, Region-Specific Extraction (RSE), produces DNA segments in excess of 20 kbp in length. Coupling this enrichment method to appropriate sequencing platforms will significantly enhance the ability to generate complete and accurate sequence characterization of any genomic region without the need for reference-based assembly. RSE is a long-range DNA target capture methodology that relies on the specific hybridization of short (20-25 base) oligonucleotide primers to selected sequence motifs within the DNA target region. These capture primers are then enzymatically extended on the 3'-end, incorporating biotinylated nucleotides into the DNA. Streptavidin-coated beads are subsequently used to pull-down the original, long DNA template molecules via the newly synthesized, biotinylated DNA that is bound to them. We demonstrate the accuracy, simplicity and utility of the RSE method by capturing and sequencing a 4 Mbp stretch of the major histocompatibility complex (MHC). Our results show an average depth of coverage of 164X for the entire MHC. This depth of coverage contributes significantly to a 99.94 % total coverage of the targeted region and to an accuracy that is over 99.99 %. RSE represents a cost-effective target enrichment method capable of producing sequencing templates in excess of 20 kbp in length. The utility of our method has been proven to generate superior coverage across the MHC as compared to other commercially available methodologies, with the added advantage of producing longer sequencing

  1. Generation of chicken Z-chromosome painting probes by microdissection for screening large-insert genomic libraries.

    Science.gov (United States)

    Zimmer, R; King, W A; Verrinder Gibbins, A M

    1997-01-01

    A strategy for rapid generation of chicken sex chromosome-Z painting probes has been developed using microdissection. Whole chromosome painting probes (WCPs) were prepared from 10-15 copies of mitotic metaphase chicken Z chromosomes. The microisolated chromosomes were subjected to PEG/proteinase K treatment in a collection drop to release DNA, which was then amplified using a degenerate oligonucleotide-primed shuttle PCR (DOP-Shuttle-PCR) strategy. Size distributions of the PCR products were analyzed by agarose gel electrophoresis and smears of DNA were revealed that ranged in size from 200-800 bp, without any evidence of preferential amplification. Both specificity and complexity of the probes have been analyzed by Southern blot and fluorescence in situ hybridization (FISH). Non-specific hybridization was efficiently blocked by using chicken competitor DNA. Analysis of the WCPs produced shows that collectively they provide uniform hybridization signals along the entire length of the chicken Z chromosome. To demonstrate one possible application of these complex probes, we screened a large-insert bacterial artificial chromosome (BAC) chicken genomic library to select Z chromosome-specific clones. To address specificity of the selected clones and to physically map them to the Z chromosome, FISH analysis was used. Of the 3 clones initially tested, one clone (C3) carrying a 250-kb insert mapped to the distal portion of the short arm of the chicken Z chromosome. Therefore, this technique has provided appropriate probes for screening large-insert genomic libraries. Further application of these probes includes the analysis of chromosome rearrangements, studies of cases of heteroploidy involving the Z chromosome, positional cloning of Z-linked genes and studies on mechanisms of sex-chromosome evolution in birds.

  2. Student Engagement in a Large Classroom: Using Technology to Generate a Hybridized Problem- Based Learning Experience in a Large First Year Undergraduate Class

    Science.gov (United States)

    Fukuzawa, Sherry; Boyd, Cleo

    2016-01-01

    Large first year undergraduate courses have unique challenges in the promotion of student engagement and self-directed learning due to resource constraints that prohibit small group discussions with instructors. The Monthly Virtual Mystery was developed to increase student engagement in a large (N = 725) first year undergraduate class in…

  3. Next Generation Very Large Array Memo No. 8 Science Working Group 3: Galaxy Assembly through Cosmic Time

    CERN Document Server

    Casey, Caitlin M; Lacy, Mark; Hales, Christopher A; Barger, Amy; Narayanan, Desika; Carilli, Chris; Alatalo, Katherine; da Cunha, Elisabete; Emonts, Bjorn; Ivison, Rob; Kimball, Amy; Kohno, Kotaro; Murphy, Eric; Riechers, Dominik; Sargent, Mark; Walter, Fabian

    2015-01-01

    The Next-Generation Very Large Array (ngVLA) will be critical for understanding how galaxies are built and evolve at the earliest epochs. The sensitivity and frequency coverage will allow for the detection of cold gas and dust in `normal' distant galaxies, including the low-J transitions of molecular gas tracers such as CO, HNC, and HCO+; synchrotron and free-free continuum emission; and even the exciting possibility of thermal dust emission at the highest (z~7) redshifts. In particular, by enabling the total molecular gas reservoirs to be traced to unprecedented sensitivities across a huge range of epochs simultaneously -- something no other radio or submillimeter facility will be capable of -- the detection of the crucial low-J transitions of CO in a diverse body of galaxies will be the cornerstone of ngVLA's contribution to high-redshift galaxy evolution science. The ultra-wide bandwidths will allow a complete sampling of radio SEDs, as well as the detection of emission lines necessary for spectroscopic co...

  4. Survey and Classification of Large Woody Debris (LWD in Streams Using Generated Low-Cost Geomatic Products

    Directory of Open Access Journals (Sweden)

    Damian Ortega-Terol

    2014-11-01

    Full Text Available Water authorities are required to have a survey of large woody debris (LWD in river channels and to manage this aspect of the stream habitat, making decisions on removing, positioning or leaving LWD in a natural state. The main objective of this study is to develop a new methodology that assists in decision making for sustainable management of river channels by using generated low-cost, geomatic products to detect LWD. The use of low-cost photogrammetry based on the use of economical, conventional, non-metric digital cameras mounted on low-cost aircrafts, together with the use of the latest computational vision techniques and open-source geomatic tools, provides useful geomatic products. The proposed methodology, compared with conventional photogrammetry or other traditional methods, led to a cost savings of up to 45%. This work presents several contributions for the area of free and open source software related to Geographic Information System (FOSSGIS applications to LWD management in streams, while developing a QGIS [1] plugin that characterizes the risk from the automatic calculation of geometrical parameters.

  5. Large-scale dynamical influence of a gravity wave generated over the Antarctic Peninsula – regional modelling and budget analysis

    Directory of Open Access Journals (Sweden)

    JOEL Arnault

    2013-03-01

    Full Text Available The case study of a mountain wave triggered by the Antarctic Peninsula on 6 October 2005, which has already been documented in the literature, is chosen here to quantify the associated gravity wave forcing on the large-scale flow, with a budget analysis of the horizontal wind components and horizontal kinetic energy. In particular, a numerical simulation using the Weather Research and Forecasting (WRF model is compared to a control simulation with flat orography to separate the contribution of the mountain wave from that of other synoptic processes of non-orographic origin. The so-called differential budgets of horizontal wind components and horizontal kinetic energy (after subtracting the results from the simulation without orography are then averaged horizontally and vertically in the inner domain of the simulation to quantify the mountain wave dynamical influence at this scale. This allows for a quantitative analysis of the simulated mountain wave's dynamical influence, including the orographically induced pressure drag, the counterbalancing wave-induced vertical transport of momentum from the flow aloft, the momentum and energy exchanges with the outer flow at the lateral and upper boundaries, the effect of turbulent mixing, the dynamics associated with geostrophic re-adjustment of the inner flow, the deceleration of the inner flow, the secondary generation of an inertia–gravity wave and the so-called baroclinic conversion of energy between potential energy and kinetic energy.

  6. Next generation sequencing and the management of diffuse large B-cell lymphoma: from whole exome analysis to targeted therapy.

    Science.gov (United States)

    Jardin, Fabrice

    2014-01-01

    Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma, accounting for 30-40% of newly diagnosed non-Hodgkin lymphomas. Historically, DLBCL has been thought to involve recurrent translocations of the IGH gene and the deregulation of rearranged oncogenes. Recent advances in next generation sequencing (NGS) have provided a vast and comprehensive catalogue of cancer genes involved in DLBCL pathogenesis. Whole exome sequencing (WES) of more than two hundred DLBCLs has completely redefined the genetic landscape of the disease by identifying recurrent single nucleotide variants and providing new therapeutic opportunities for the germinal center B-cell like (GCB), activated B-cell like (ABC), or primary mediastinal B-cell (PMBL) molecular subtypes. Some of these somatic mutations target genes that play a crucial role in B-cell function (BCR signaling, NF-κB pathway, NOTCH signaling, Toll-like receptor signaling, and the PI3K pathway), immunity, cell cycle/apoptosis, or chromatin modification. In this review, we present an overview of the mutations recently discovered by NGS in DLBCL and discuss their biological relevance and possible impacts on clinical management.

  7. Implementation Status of a Ultra-Wideband Receiver Package for the next-generation Very Large Array

    Science.gov (United States)

    Lazio, T. Joseph W.; Velazco, Jose; Soriano, Melissa; Hoppe, Daniel; Russell, Damon; D'Addario, Larry; Long, Ezra; Bowen, James; Samoska, Lorene; Janzen, Andrew

    2017-01-01

    The next-generation Very Large Array (ngVLA) is a concept for a radio astronomical interferometric array operating in the frequency range 1.2 GHz to 116 GHz and designed to provide substantial improvements in sensitivity, angular resolution, and frequency coverage above the current Very Large Array (VLA). As notional design goals, it would have a continuous frequency coverage of 1.2 GHz to 48 GHz and be 10 times more sensitive than the VLA (and 25 times more sensitive than a 34 m diameter antenna of the Deep Space Network [DSN]). One of the key goals for the ngVLA is to reduce the operating costs without sacrificing performance. We are designing an ultra-wideband receiver package designed to operate across the 8 to 48 GHz frequency range, which can be contrasted to the current VLA, which covers this frequency range with five receiver packages. Reducing the number of receiving systems required to cover the full frequency range would reduce operating costs, and the objective of this work is to develop a prototype integrated feed-receiver package with a sensitivity performance comparable to current narrower band systems on radio telescopes and the DSN, but with a design that meets the requirement of low long-term operational costs. The ultra-wideband receiver package consists of a feed horn, low-noise amplifier (LNA), and down-converters to analog intermediate frequencies. Key features of this design are a quad-ridge feed horn with dielectric loading and a cryogenic receiver with a noise temperature of no more than 30 K at the low end of the band. We will report on the status of this receiver package development including the feed design and LNA implementation. We will present simulation studies of the feed horn including the insertion of dielectric components for improved illumination efficiencies across the band of interest. In addition, we will show experimental results of low-noise 35nm InP HEMT amplifier testing performed across the 8-50 GHz frequency range

  8. Saturation Ion Current Densities in Inductively Coupled Hydrogen Plasma Produced by Large-Power Radio Frequency Generator

    Science.gov (United States)

    Wang, Songbai; Lei, Guangjiu; Bi, Zhenhua; Ghomi, H.; Yang, Size; Liu, Dongping

    2016-09-01

    An experimental investigation of the saturation ion current densities (Jions) in hydrogen inductively coupled plasma (ICP) produced by a large-power (2-32 kW) radio frequency (RF) generator is reported, then some reasonable explanations are given out. With the increase of RF power, the experimental results show three stages: in the first stage (2-14 kW), the electron temperature will rise with the increase of RF power in the ICP, thus, the Jions increases continually as the electron temperature rises in the ICP. In the second stage (14-20 kW), as some H- ions lead to the mutual neutralization (MN), the slope of Jions variation firstly decreases then increases. In the third stage (20-32 kW), both the electronic detachment (ED) and the associative detachment (AD) in the ICP result in the destruction of H- ions, therefore, the increased amplitude of the Jions in the third stage is weaker than the one in the first stage. In addition, with the equivalent transformer model, we successfully explain that the Jions at different radial locations in ICP has the same rule. Finally, it is found that the Jions has nothing to do with the outer/inner puffing gas pressure ratio, which is attributed to the high-speed movement of hydrogen molecules. supported by the National Magnetic Confinement Fusion Science Program of China (Nos. 2011GB108011 and 2010GB103001), the Major International (Regional) Project Cooperation and Exchanges of China (No. 11320101005) and the Startup Fund from Fuzhou University (No. 510071)

  9. Evaluation of the Genetic Basis of Familial Aggregation of Pacemaker Implantation by a Large Next Generation Sequencing Panel.

    Directory of Open Access Journals (Sweden)

    Patrícia B S Celestino-Soper

    Full Text Available The etiology of conduction disturbances necessitating permanent pacemaker (PPM implantation is often unknown, although familial aggregation of PPM (faPPM suggests a possible genetic basis. We developed a pan-cardiovascular next generation sequencing (NGS panel to genetically characterize a selected cohort of faPPM.We designed and validated a custom NGS panel targeting the coding and splicing regions of 246 genes with involvement in cardiac pathogenicity. We enrolled 112 PPM patients and selected nine (8% with faPPM to be analyzed by NGS.Our NGS panel covers 95% of the intended target with an average of 229x read depth at a minimum of 15-fold depth, reaching a SNP true positive rate of 98%. The faPPM patients presented with isolated cardiac conduction disease (ICCD or sick sinus syndrome (SSS without overt structural heart disease or identifiable secondary etiology. Three patients (33.3% had heterozygous deleterious variants previously reported in autosomal dominant cardiac diseases including CCD: LDB3 (p.D117N and TRPM4 (p.G844D variants in patient 4; TRPM4 (p.G844D and ABCC9 (p.V734I variants in patient 6; and SCN5A (p.T220I and APOB (p.R3527Q variants in patient 7.FaPPM occurred in 8% of our PPM clinic population. The employment of massive parallel sequencing for a large selected panel of cardiovascular genes identified a high percentage (33.3% of the faPPM patients with deleterious variants previously reported in autosomal dominant cardiac diseases, suggesting that genetic variants may play a role in faPPM.

  10. Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study.

    Science.gov (United States)

    Dubois, Sydney; Viailly, Pierre-Julien; Mareschal, Sylvain; Bohers, Elodie; Bertrand, Philippe; Ruminy, Philippe; Maingonnat, Catherine; Jais, Jean-Philippe; Peyrouze, Pauline; Figeac, Martin; Molina, Thierry J; Desmots, Fabienne; Fest, Thierry; Haioun, Corinne; Lamy, Thierry; Copie-Bergman, Christiane; Brière, Josette; Petrella, Tony; Canioni, Danielle; Fabiani, Bettina; Coiffier, Bertrand; Delarue, Richard; Peyrade, Frédéric; Bosly, André; André, Marc; Ketterer, Nicolas; Salles, Gilles; Tilly, Hervé; Leroy, Karen; Jardin, Fabrice

    2016-06-15

    Next-generation sequencing (NGS) has detailed the genomic characterization of diffuse large B-cell lymphoma (DLBCL) by identifying recurrent somatic mutations. We set out to design a clinically feasible NGS panel focusing on genes whose mutations hold potential therapeutic impact. Furthermore, for the first time, we evaluated the prognostic value of these mutations in prospective clinical trials. A Lymphopanel was designed to identify mutations in 34 genes, selected according to literature and a whole exome sequencing study of relapsed/refractory DLBCL patients. The tumor DNA of 215 patients with CD20(+)de novo DLBCL in the prospective, multicenter, and randomized LNH-03B LYSA clinical trials was sequenced to deep, uniform coverage with the Lymphopanel. Cell-of-origin molecular classification was obtained through gene expression profiling with HGU133+2.0 Affymetrix GeneChip arrays. The Lymphopanel was informative for 96% of patients. A clear depiction of DLBCL subtype molecular heterogeneity was uncovered with the Lymphopanel, confirming that activated B-cell-like (ABC), germinal center B-cell like (GCB), and primary mediastinal B-cell lymphoma (PMBL) are frequently affected by mutations in NF-κB, epigenetic, and JAK-STAT pathways, respectively. Novel truncating immunity pathway, ITPKB, MFHAS1, and XPO1 mutations were identified as highly enriched in PMBL. Notably, TNFAIP3 and GNA13 mutations in ABC patients treated with R-CHOP were associated with significantly less favorable prognoses. This study demonstrates the contribution of NGS with a consensus gene panel to personalized therapy in DLBCL, highlighting the molecular heterogeneity of subtypes and identifying somatic mutations with therapeutic and prognostic impact. Clin Cancer Res; 22(12); 2919-28. ©2016 AACRSee related commentary by Lim and Elenitoba-Johnson, p. 2829. ©2016 American Association for Cancer Research.

  11. Effect of wind turbine generator model and siting on wind power changes out of large WECS arrays

    Science.gov (United States)

    Schleuter, R. A.; Park, G. L.; Lotfalian, M.; Dorsey, J.; Shayanfar, H.

    1981-01-01

    Methods of reducing the WECS generation change through selection of the wind turbine model for each site, selection of an appropriate siting configuration, and wind array controls are discussed. An analysis of wind generation change from an echelon and a farm for passage of a thunderstorm is presented. Reduction of the wind generation change over ten minutes is shown to reduce the increase in spinning reserve, unloadable generation and load following requirements on unit commitment when significant WECS generation is present and the farm penetration constraint is satisfied. Controls on the blade pitch angle of all wind turbines in an array or a battery control are shown to reduce both the wind generation change out of an array and the effective farm penetration in anticipation of a storm so that the farm penetration constraint may be satisfied.

  12. Synchronization of the ERDA-NASA 100 LkW wind turbine generator with large utility networks

    Science.gov (United States)

    Hwang, H. H.; Gilbert, L. J.

    1977-01-01

    The synchronizing of a wind turbine generator against an infinite bus under random conditions is studied. With a digital computer, complete solutions for rotor speed, generator power angle, electromagnetic torque, wind turbine torque, wind turbine blade pitch angle, and armature current are obtained and presented by graphs.

  13. Generation IV nuclear energy system initiative. Large GFR core subassemblydesign for the Gas-Cooled Fast Reactor.

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, E. A.; Kulak, R. F.; Therios, I. U.; Wei, T. Y. C.

    2006-07-31

    Gas-cooled fast reactor (GFR) designs are being developed to meet Gen IV goals of sustainability, economics, safety and reliability, and proliferation resistance and physical protection as part of an International Generation IV Nuclear Energy System Research Initiative effort. Different organizations are involved in the development of a variety of GFR design concepts. The current analysis has focused on the evaluation of low-pressure drop, pin-core designs with favorable passive cooling properties. Initial evaluation of the passive cooling safety case for the GFR during depressurized decay heat removal accidents with concurrent loss of electric power have resulted in requirements for a reduction of core power density to the 100 w/cc level and a low core pressure drop of 0.5 bars. Additional design constraints and the implementation of their constraints are evaluated in this study to enhance and passive cooling properties of the reactor. Passive cooling is made easier by a flat radial distribution of the decay heat. One goal of this study was to evaluate the radial power distribution and determine to what extent it can be flattened, since the decay heat is nearly proportional to the fission power at shutdown. In line with this investigation of the radial power profile, an assessment was also made of the control rod configuration. The layout provided a large number of control rod locations with a fixed area provided for control rods. The number of control rods was consistent with other fast reactor designs. The adequacy of the available control rod locations was evaluated. Future studies will be needed to optimize the control rod designs and evaluate the shutdown system. The case for low pressure drop core can be improved by the minimization of pressure drop sources such as the number of required fuel spacers in the subassembly design and by the details of the fuel pin design. The fuel pin design is determined by a number of neutronic, thermal-hydraulic (gas dynamics

  14. On Matrix Sampling and Imputation of Context Questionnaires with Implications for the Generation of Plausible Values in Large-Scale Assessments

    Science.gov (United States)

    Kaplan, David; Su, Dan

    2016-01-01

    This article presents findings on the consequences of matrix sampling of context questionnaires for the generation of plausible values in large-scale assessments. Three studies are conducted. Study 1 uses data from PISA 2012 to examine several different forms of missing data imputation within the chained equations framework: predictive mean…

  15. Student Engagement in a Large Classroom: Using Technology to Generate a Hybridized Problem-based Learning Experience in a Large First Year Undergraduate Class

    Directory of Open Access Journals (Sweden)

    Sherry Fukuzawa

    2016-06-01

    Full Text Available Large first year undergraduate courses have unique challenges in the promotion of student engagement and self-directed learning due to resource constraints that prohibit small group discussions with instructors. The Monthly Virtual Mystery was developed to increase student engagement in a large (N = 725 first year undergraduate class in anthropology at the University of Toronto Mississauga. The teaching challenge was to develop a participation component (worth 6% of the final grade that would increase student engagement without incurring any additional resource costs. The goal of the virtual mystery was to incorporate the principles of problem-based learning to engage students in self-directed learning through an online medium. Groups of approximately 50 students collaborated on a series of “virtual” case studies in a discussion board. Students submitted comments or questions each week to identify the information they needed to solve the mystery. A facilitator oversaw the discussion board to guide students in collaboration and resource acquisition. The final grades of students who participated in the virtual mystery (N=297 were compared to students who participated in a passive online learning exercise that involved watching weekly online videos and answering questions in a course reader (N = 347. Student self-selection determined group participation. Participation completion for both the virtual mystery and the course reader were high (78.8% and 91.6% respectively. There were no significant differences in the distribution of final grades between the participation options. The high completion rate of the virtual mystery demonstrated that an active learning project can be implemented using problem-based learning principles through an online discussion board; however, the large online group collaborations were problematic. Students were frustrated with repetition and inequitable participation in such large groups; however, students evaluated

  16. Large magnetocaloric effect in a dense and stable inorganic-organic hybrid cobridged by in situ generated sulfate and oxalate.

    Science.gov (United States)

    Han, Song-De; Miao, Xiao-Hong; Liu, Sui-Jun; Bu, Xian-He

    2014-11-01

    A dense and stable inorganic-organic hybrid with distorted cubic [Gd4O4] units as building blocks bridged by in situ generated sulfate and oxalate was synthesized. Magnetic measurements indicate that the title complex features a -ΔS(m)(max)=51.49 J kg(-1) K(-1), which is among the highest values reported so far.

  17. Method for generation of THz frequency radiation and sensing of large amplitude material strain waves in piezoelectric materials

    Science.gov (United States)

    Reed, Evan J.; Armstrong, Michael R.

    2010-09-07

    Strain waves of THz frequencies can coherently generate radiation when they propagate past an interface between materials with different piezoelectric coefficients. Such radiation is of detectable amplitude and contains sufficient information to determine the time-dependence of the strain wave with unprecedented subpicosecond, nearly atomic time and space resolution.

  18. 大容量发电机出口断路器选择%Circuit Breakers Selection Method for Large-capacity AC High-voltage Generator

    Institute of Scientific and Technical Information of China (English)

    张爽

    2011-01-01

    针对大容量发电机出口断路器的选择问题,依据GB/T 14824-2008、IEEE Std C37.013-1997和IEC 60909-0-2001中的计算方法,并结合发电机出口断路器型式试验报告的有关数据,以某百万千瓦级发电机组为例进行了比较计算,分析计算结果,提出了对发电机出口短路器短路电流开断能力不能采用百分比而应采用绝对值进行校验.%For selecting large-capacity AC high-voltage generator circuit breakers in a large generator system, comparative calculations are conducted for a million kilowatts rated generator following the standards of GB/T 14824-2008, IEEE Std C37.013-1997 and IEC 60909-0-2001. The calculation results and the test reports of generator circuit breakers are analyzed, and a suggestion is hence offered that absolute value of short-circuit current should be used for examining the short-circuit current breaking capacity of an AC high-voltage generator circuit breaker instead of percentage value.

  19. Response measurements for two building structures excited by noise from a large horizontal axis wind turbine generator

    Science.gov (United States)

    Hubbard, H. H.; Shepherd, K. P.

    1984-01-01

    Window and wall acceleration measurements and interior noise measurements ere made for two different building structures during excitation by noise from the WTS-4 horizontal axis wind turbine generator operating in a normal power generation mode. With turbine noise input pulses resulted in acceleration pulses for the wall and window elements of the two tests buildings. Response spectra suggest that natural vibration modes of the structures are excited. Responses of a house trailer were substantially greater than those for a building of sturdier construction. Peak acceleration values correlate well with similar data for houses excited by flyover noise from commercial and military airplanes and helicopters, and sonic booms from supersonic aircraft. Interior noise spectra have peaks at frequencies corresponding to structural vibration modes and room standing waves; and the levels for particular frequencies and locations can be higher than the outside levels.

  20. A molecular copper catalyst for electrochemical water reduction with a large hydrogen-generation rate constant in aqueous solution.

    Science.gov (United States)

    Zhang, Peili; Wang, Mei; Yang, Yong; Yao, Tianyi; Sun, Licheng

    2014-12-08

    The copper complex [(bztpen)Cu](BF4)2 (bztpen=N-benzyl-N,N',N'-tris(pyridin-2-ylmethyl)ethylenediamine) displays high catalytic activity for electrochemical proton reduction in acidic aqueous solutions, with a calculated hydrogen-generation rate constant (k(obs)) of over 10000 s(-1). A turnover frequency (TOF) of 7000 h(-1) cm(-2) and a Faradaic efficiency of 96% were obtained from a controlled potential electrolysis (CPE) experiment with [(bztpen)Cu](2+) in pH 2.5 buffer solution at -0.90 V versus the standard hydrogen electrode (SHE) over two hours using a glassy carbon electrode. A mechanism involving two proton-coupled reduction steps was proposed for the dihydrogen generation reaction catalyzed by [(bztpen)Cu](2+).

  1. Dynamic wave field synthesis: enabling the generation of field distributions with a large space-bandwidth product

    OpenAIRE

    Kamau, Edwin Ngugi

    2016-01-01

    The generation and manipulation of electromagnetic field distributions plays an essential role in physics in general, and particularly in the vast field of physical optics. In the current state of the art, one of the most convenient methods of performing this task is provided by either static or dynamic diffractive as well as holographic optical elements. Currently available dynamic optical elements, such as spatial light modulators, do offer on the one hand high temporal flexibility. They ho...

  2. An Optimized Combination of a Large Grid Connected PV System along with Battery Cells and a Diesel Generator

    OpenAIRE

    2016-01-01

    Environmental, economical and technical benefits of photovoltaic (PV) systems make them to be used in many countries. The main characteristic of PV systems is the fluctuations of their output power. Hence, high penetration of PV systems into electric network could be detrimental to overall system performance. Furthermore, the fluctuations in the output power of PV systems make it difficult to predict their output, and to consider them in generation planning of the units. The main objective of...

  3. Generation of ultra-large-bandwidth X-ray free-electron-laser pulses with a transverse-gradient undulator.

    Science.gov (United States)

    Prat, Eduard; Calvi, Marco; Reiche, Sven

    2016-07-01

    A new and simple method to generate X-ray free-electron-laser radiation with unprecedented spectral bandwidth above the 10% level is presented. The broad bandwidth is achieved by sending a transversely tilted beam through a transverse-gradient undulator. The extent of the bandwidth can easily be controlled by variation of the beam tilt or the undulator gradient. Numerical simulations confirm the validity and feasibility of this method.

  4. Dynamic wave field synthesis: enabling the generation of field distributions with a large space-bandwidth product

    OpenAIRE

    Kamau, Edwin Ngugi

    2016-01-01

    The generation and manipulation of electromagnetic field distributions plays an essential role in physics in general, and particularly in the vast field of physical optics. In the current state of the art, one of the most convenient methods of performing this task is provided by either static or dynamic diffractive as well as holographic optical elements. Currently available dynamic optical elements, such as spatial light modulators, do offer on the one hand high temporal flexibility. They ho...

  5. High efficiency, high energy second-harmonic generation of Nd glass laser radiation in large aperture CsLiB sub 6 O sub 1 sub 0 crystals

    CERN Document Server

    Kiriyama, H; Yamakawa, K

    2002-01-01

    We have demonstrated the generation of a high-energy green laser pulse using large aperture CsLiB sub 6 O sub 1 sub 0 (CLBO) crystals. A pulsed energy of 25 J at 532-nm was generated using the 1064-nm incident Nd:glass laser radiation with an energy of 34 J. High conversion efficiency of 74% at intensities of only 370 MW/cm sup 2 was obtained using a two-stage crystal architecture. This result represents the highest green pulse energy ever reported using the CLBO crystals. We discuss in detail the design and performance of SHG using CLBO crystals.

  6. Energisation of Wind Turbine Transformers with an Auxiliary Generator in a Large Offshore Wind Farm Under Islanded Operation

    DEFF Research Database (Denmark)

    Arana Aristi, Iván; Hernandez, Alvaro; Thumm, Gerhard

    2011-01-01

    The prospective inrush currents during the energization of wind turbine transformers in a large offshore wind farm during islanded operation were estimated by time-domain simulations covering different energizing scenarios. In this way, worst case procedures could be identified. The energization ...

  7. Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model.

    NARCIS (Netherlands)

    Tatara, A.M.; Kretlow, J.D.; Spicer, P.P.; Lu, S.; Lam, J.; Liu, W.; Cao, Y.; Liu, G.; Jackson, J.D.; Yoo, J.J.; Atala, A.; Beucken, J.J.J.P van den; Jansen, J.A.; Kasper, F.K.; Ho, T.; Demian, N.; Miller, M.J.; Wong, M.E.; Mikos, A.G.

    2015-01-01

    The reconstruction of large craniofacial defects remains a significant clinical challenge. The complex geometry of facial bone and the lack of suitable donor tissue often hinders successful repair. One strategy to address both of these difficulties is the development of an in vivo bioreactor, where

  8. The magnetic shear-current effect: generation of large-scale magnetic fields by the small-scale dynamo

    Science.gov (United States)

    Squire, J.; Bhattacharjee, A.

    2016-04-01

    > A novel large-scale dynamo mechanism, the magnetic shear-current effect, is discussed and explored. The effect relies on the interaction of magnetic fluctuations with a mean shear flow, meaning the saturated state of the small-scale dynamo can drive a large-scale dynamo - in some sense the inverse of dynamo quenching. The dynamo is non-helical, with the mean field coefficient zero, and is caused by the interaction between an off-diagonal component of the turbulent resistivity and the stretching of the large-scale field by shear flow. Following up on previous numerical and analytic work, this paper presents further details of the numerical evidence for the effect, as well as an heuristic description of how magnetic fluctuations can interact with shear flow to produce the required electromotive force. The pressure response of the fluid is fundamental to this mechanism, which helps explain why the magnetic effect is stronger than its kinematic cousin, and the basic idea is related to the well-known lack of turbulent resistivity quenching by magnetic fluctuations. As well as being interesting for its applications to general high Reynolds number astrophysical turbulence, where strong small-scale magnetic fluctuations are expected to be prevalent, the magnetic shear-current effect is a likely candidate for large-scale dynamo in the unstratified regions of ionized accretion disks. Evidence for this is discussed, as well as future research directions and the challenges involved with understanding details of the effect in astrophysically relevant regimes.

  9. Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model.

    NARCIS (Netherlands)

    Tatara, A.M.; Kretlow, J.D.; Spicer, P.P.; Lu, S.; Lam, J.; Liu, W.; Cao, Y.; Liu, G.; Jackson, J.D.; Yoo, J.J.; Atala, A.; Beucken, J.J.J.P van den; Jansen, J.A.; Kasper, F.K.; Ho, T.; Demian, N.; Miller, M.J.; Wong, M.E.; Mikos, A.G.

    2015-01-01

    The reconstruction of large craniofacial defects remains a significant clinical challenge. The complex geometry of facial bone and the lack of suitable donor tissue often hinders successful repair. One strategy to address both of these difficulties is the development of an in vivo bioreactor, where

  10. Improvement of the decay heat removal characteristics of the generation IV gas-cooled fast reactor; Amelioration des caracteristiques de la dissipation de la chaleur de decroissance pour les reacteurs a neutrons rapides de quatrieme generation refroidi au gaz

    Energy Technology Data Exchange (ETDEWEB)

    Epiney, A.S.

    2010-09-07

    The main drawback of the GFR is the difficulty to evacuate decay heat following a loss-of-coolant accident (LOCA) due to the low thermal inertia of the core, as well as to the low coolant density. The present doctoral research focuses on the improvement of decay heat removal (DHR) for the Generation-IV GFR. The reference GFR system design considered in the thesis is the 2006 CEA concept, with a power of 2400 MWth. The CEA 2006 DHR strategy foresees, in all accidental cases (independent of the system pressure), that the reactor is shut down. For high pressure events, dedicated DHR loops with blowers and heat exchangers are designed to operate when the power conversion system cannot be used to provide acceptable core temperatures under natural convection conditions. For de-pressurized events, the strategy relies on a dedicated small containment (called the guard containment) providing an intermediate back-up pressure. The DHR blowers, designed to work under these pressure conditions, need to be powered either by the power grid or by batteries for at least 24 hours. The specific contributions of the present research - aimed at achieving enhanced passivity of the DHR system for the GFR - are design and analysis related to (1) the injection of heavy gas into the primary circuit after a LOCA, to enable natural convection cooling at an intermediate-pressure level, and (2) an autonomous Brayton loop to evacuate decay heat at low primary pressure in case of a loss of the guard containment pressure. Both these developments reduce the dependence on blower power availability considerably. First, the thermal-hydraulic codes used in the study - TRACE and CATHARE - are validated for gas cooling. The validation includes benchmark comparisons between the codes, serving to identify the sensitivity of the results to the different modeling assumptions. The parameters found to be the most sensitive in this analysis, such as heat transfer and friction models, are then validated via a

  11. Transcriptome sequencing of lentil based on second-generation technology permits large-scale unigene assembly and SSR marker discovery

    Directory of Open Access Journals (Sweden)

    Materne Michael

    2011-05-01

    Full Text Available Abstract Background Lentil (Lens culinaris Medik. is a cool-season grain legume which provides a rich source of protein for human consumption. In terms of genomic resources, lentil is relatively underdeveloped, in comparison to other Fabaceae species, with limited available data. There is hence a significant need to enhance such resources in order to identify novel genes and alleles for molecular breeding to increase crop productivity and quality. Results Tissue-specific cDNA samples from six distinct lentil genotypes were sequenced using Roche 454 GS-FLX Titanium technology, generating c. 1.38 × 106 expressed sequence tags (ESTs. De novo assembly generated a total of 15,354 contigs and 68,715 singletons. The complete unigene set was sequence-analysed against genome drafts of the model legume species Medicago truncatula and Arabidopsis thaliana to identify 12,639, and 7,476 unique matches, respectively. When compared to the genome of Glycine max, a total of 20,419 unique hits were observed corresponding to c. 31% of the known gene space. A total of 25,592 lentil unigenes were subsequently annoated from GenBank. Simple sequence repeat (SSR-containing ESTs were identified from consensus sequences and a total of 2,393 primer pairs were designed. A subset of 192 EST-SSR markers was screened for validation across a panel 12 cultivated lentil genotypes and one wild relative species. A total of 166 primer pairs obtained successful amplification, of which 47.5% detected genetic polymorphism. Conclusions A substantial collection of ESTs has been developed from sequence analysis of lentil genotypes using second-generation technology, permitting unigene definition across a broad range of functional categories. As well as providing resources for functional genomics studies, the unigene set has permitted significant enhancement of the number of publicly-available molecular genetic markers as tools for improvement of this species.

  12. The magnetic shear-current effect: generation of large-scale magnetic fields by the small-scale dynamo

    CERN Document Server

    Squire, Jonathan

    2015-01-01

    A novel large-scale dynamo mechanism, the magnetic shear-current effect, is discussed and explored. The effect relies on the interaction of magnetic fluctuations with a mean shear flow, meaning the saturated state of the small-scale dynamo can drive a large-scale dynamo -- in some sense the inverse of dynamo quenching. The dynamo is nonhelical, with the mean-field $\\alpha$ coefficient zero, and is caused by the interaction between an off-diagonal component of the turbulent resistivity and the stretching of the large-scale field by shear flow. Following up on previous numerical and analytic work, this paper presents further details of the numerical evidence for the effect, as well as an heuristic description of how magnetic fluctuations can interact with shear flow to produce the required electromotive force. The pressure response of the fluid is fundamental to this mechanism, which helps explain why the magnetic effect is stronger than its kinematic cousin, and the basic idea is related to the well-known lack...

  13. Development and field tests of a damping controller to mitigate electromechanical oscillations on large diesel generating units

    Energy Technology Data Exchange (ETDEWEB)

    Nogueira, Fabricio G.; Barreiros, Jose A.L.; Barra, Walter Jr.; Costa, Carlos T. Jr. [Universidade Federal do Para (UFPA), Instituto de Tecnologia, Faculdade de Engenharia Eletrica, Campus Universitario do Guama, CEP: 66075-900, Belem (Brazil); Ferreira, Andre M.D. [Instituto Federal de Educacao, Ciencia e Tecnologia do Para (IFPA), Campus Belem, Departamento de Controle e Processos Industriais, Av. Almirante Barroso, 1155 (Marco), CEP: 66093-020, Belem (Brazil)

    2011-02-15

    This paper presents the development and field tests of a digital damping controller designed to mitigate intra-plant electromechanical oscillations via the speed governor system of fast acting units. The controller performance is assessed on an 18-MVA diesel generating unit, at Santana Power Plant (Amapa State, Amazon Region at Northern Brazil). In order to design the damping control law, a set of parametric ARX models representing the plant dynamics at several load conditions, are previously identified from data collected on field tests. The damping controller gains are calculated by using the identified ARX models parameters as inputs to a discrete-time pole-placement design method (pole-shifting) and then embedded on a DSP based microcontroller digital system, for field tests assessment. The digital damping controller modulates the diesel engine inlet valve position according to the observed oscillation on the measured electric power, using a PWM device, which is specially developed to this application. The experimental results shown the good performance of the developed controller on damping efficiently the electromechanical oscillations observed between generating units at Santana Power Plant. (author)

  14. Dynamic wave field synthesis: enabling the generation of field distributions with a large space-bandwidth product.

    Science.gov (United States)

    Kamau, Edwin N; Heine, Julian; Falldorf, Claas; Bergmann, Ralf B

    2015-11-02

    We present a novel approach for the design and fabrication of multiplexed computer generated volume holograms (CGVH) which allow for a dynamic synthesis of arbitrary wave field distributions. To achieve this goal, we developed a hybrid system that consists of a CGVH as a static element and an electronically addressed spatial light modulator as the dynamic element. We thereby derived a new model for describing the scattering process within the inhomogeneous dielectric material of the hologram. This model is based on the linearization of the scattering process within the Rytov approximation and incorporates physical constraints that account for voxel based laser-lithography using micro-fabrication of the holograms in a nonlinear optical material. In this article we demonstrate that this system basically facilitates a high angular Bragg selectivity on the order of 1°. Additionally, it allows for a qualitatively low cross-talk dynamic synthesis of predefined wave fields with a much larger space-bandwidth product (SBWP ≥ 8.7 × 10(6)) as compared to the current state of the art in computer generated holography.

  15. Yunnan’s Fast-Paced Large Hydropower Development: A Powershed-Based Approach to Critically Assessing Generation and Consumption Paradigms

    Directory of Open Access Journals (Sweden)

    Thomas Hennig

    2016-10-01

    Full Text Available Southwest China’s Yunnan province is evolving into one of the world’s largest hydro-power-producing regions. It already rivals the world’s largest hydro-producing nations. However, five of Yunnan’s six basins are international and therefore its hydropower development is of great academic and geopolitical interest. While the implementation of large projects on Yunnan’s three large rivers (Jinsha, Mekong and Nu is relatively well studied, hydropower development outside these three main streams is hardly known. Here, we identified 128 large hydropower projects (≥50 MW having a capacity of 16.5 GW, along with another 16.4 GW of other types of power generation, neither of which has been discussed in the academic literature yet. The paper utilizes a powershed approach to study the rapid hydropower development underway in Yunnan, both in its implication and challenges (at basin and administrative level as well as in its trade-offs within the broader electricity context. Yunnan’s power generation and consumption patterns are characterized by diverging interests of local/provincial usage and export utilization. Within the province, the largest (hydro- power users are energy/electricity intensive industries, which themselves have strong impacts on land use changes. Yunnan is also evolving as a major power exporter, already in 2013 exporting about one-third of its generated electricity mainly to Guangdong’s Pearl River Delta. We see a need for a critical revision of those existing generation and consumption paradigms, which includes a rethinking of major development modes, both in terms of future hydropower generation and utilization projects as well as export obligations.

  16. Fault detection on the Large Hadron Collider at CERN: design, simulation and realization of a High Voltage Pulse Generator

    CERN Document Server

    Cavicchioli, C; Biagi, E; Bozzini, D

    2007-01-01

    This project was developed inside the Quality Assurance Plan (ELQA) of the LHC. The superconducting circuits of the collider show a great complexity concerning the control system, because of various reasons: the tunnel is placed around 50 to 175 m underground, the circuits work at temperatures of 1.9 K, all the structure should be perfectly aligned and the electronic part has considerable dimensions. To maximize the running time of the collider, it is necessary to develop methods for the diagnostic of defects and for the precise localization of the segment of the accelerator that contains the fault. From my studies it emerged that a possible way to localize electrical faults in the LHC superconducting circuits is to combine the use of time domain reflectometry methods and high voltage pulses. Therefore, I have designed and realized a high voltage pulse generator that will be an important instrument for the fault location among the accelerator.

  17. ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider

    CERN Document Server

    Aad, Georges; Abdallah, Jalal; Abdinov, Ovsat; Aben, Rosemarie; Abolins, Maris; AbouZeid, Ossama; Abramowicz, Halina; Abreu, Henso; Abreu, Ricardo; Abulaiti, Yiming; Acharya, Bobby Samir; Adamczyk, Leszek; Adams, David; Adelman, Jahred; Adomeit, Stefanie; Adye, Tim; Affolder, Tony; Agatonovic-Jovin, Tatjana; Agricola, Johannes; Aguilar-Saavedra, Juan Antonio; Ahlen, Steven; Ahmadov, Faig; Aielli, Giulio; Akerstedt, Henrik; Åkesson, Torsten Paul Ake; Akimov, Andrei; Alberghi, Gian Luigi; Albert, Justin; Albrand, Solveig; Alconada Verzini, Maria Josefina; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexopoulos, Theodoros; Alhroob, Muhammad; Alimonti, Gianluca; Alio, Lion; Alison, John; Alkire, Steven Patrick; Allbrooke, Benedict; Allport, Phillip; Aloisio, Alberto; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Altheimer, Andrew David; Alvarez Gonzalez, Barbara; Άlvarez Piqueras, Damián; Alviggi, Mariagrazia; Amadio, Brian Thomas; Amako, Katsuya; Amaral Coutinho, Yara; Amelung, Christoph; Amidei, Dante; Amor Dos Santos, Susana Patricia; Amorim, Antonio; Amoroso, Simone; Amram, Nir; Amundsen, Glenn; Anastopoulos, Christos; Ancu, Lucian Stefan; Andari, Nansi; Andeen, Timothy; Anders, Christoph Falk; Anders, Gabriel; Anders, John Kenneth; Anderson, Kelby; Andreazza, Attilio; Andrei, George Victor; Angelidakis, Stylianos; Angelozzi, Ivan; Anger, Philipp; Angerami, Aaron; Anghinolfi, Francis; Anisenkov, Alexey; Anjos, Nuno; Annovi, Alberto; Antonelli, Mario; Antonov, Alexey; Antos, Jaroslav; Anulli, Fabio; Aoki, Masato; Aperio Bella, Ludovica; Arabidze, Giorgi; Arai, Yasuo; Araque, Juan Pedro; Arce, Ayana; Arduh, Francisco Anuar; Arguin, Jean-Francois; Argyropoulos, Spyridon; Arik, Metin; Armbruster, Aaron James; Arnaez, Olivier; Arnal, Vanessa; Arnold, Hannah; Arratia, Miguel; Arslan, Ozan; Artamonov, Andrei; Artoni, Giacomo; Asai, Shoji; Asbah, Nedaa; Ashkenazi, Adi; Åsman, Barbro; Asquith, Lily; Assamagan, Ketevi; Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Auerbach, Benjamin; Augsten, Kamil; Aurousseau, Mathieu; Avolio, Giuseppe; Axen, Bradley; Ayoub, Mohamad Kassem; Azuelos, Georges; Baak, Max; Baas, Alessandra; Baca, Matthew John; Bacci, Cesare; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Backhaus, Malte; Bagiacchi, Paolo; Bagnaia, Paolo; Bai, Yu; Bain, Travis; Baines, John; Baker, Oliver Keith; Baldin, Evgenii; Balek, Petr; Balestri, Thomas; Balli, Fabrice; Banas, Elzbieta; Banerjee, Swagato; Bannoura, Arwa A E; Bansil, Hardeep Singh; Barak, Liron; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisonzi, Marcello; Barklow, Timothy; Barlow, Nick; Barnes, Sarah Louise; Barnett, Bruce; Barnett, Michael; Barnovska, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Basalaev, Artem; Bassalat, Ahmed; Basye, Austin; Bates, Richard; Batista, Santiago Juan; Batley, Richard; Battaglia, Marco; Bauce, Matteo; Bauer, Florian; Bawa, Harinder Singh; Beacham, James Baker; Beattie, Michael David; Beau, Tristan; Beauchemin, Pierre-Hugues; Beccherle, Roberto; Bechtle, Philip; Beck, Hans Peter; Becker, Kathrin; Becker, Maurice; Becker, Sebastian; Beckingham, Matthew; Becot, Cyril; Beddall, Andrew; Beddall, Ayda; Bednyakov, Vadim; Bee, Christopher; Beemster, Lars; Beermann, Thomas; Begel, Michael; Behr, Janna Katharina; Belanger-Champagne, Camille; Bell, William; Bella, Gideon; Bellagamba, Lorenzo; Bellerive, Alain; Bellomo, Massimiliano; Belotskiy, Konstantin; Beltramello, Olga; Benary, Odette; Benchekroun, Driss; Bender, Michael; Bendtz, Katarina; Benekos, Nektarios; Benhammou, Yan; Benhar Noccioli, Eleonora; Benitez Garcia, Jorge-Armando; Benjamin, Douglas; Bensinger, James; Bentvelsen, Stan; Beresford, Lydia; Beretta, Matteo; Berge, David; Bergeaas Kuutmann, Elin; Berger, Nicolas; Berghaus, Frank; Beringer, Jürg; Bernard, Clare; Bernard, Nathan Rogers; Bernius, Catrin; Bernlochner, Florian Urs; Berry, Tracey; Berta, Peter; Bertella, Claudia; Bertoli, Gabriele; Bertolucci, Federico; Bertsche, Carolyn; Bertsche, David; Besana, Maria Ilaria; Besjes, Geert-Jan; Bessidskaia Bylund, Olga; Bessner, Martin Florian; Besson, Nathalie; Betancourt, Christopher; Bethke, Siegfried; Bevan, Adrian John; Bhimji, Wahid; Bianchi, Riccardo-Maria; Bianchini, Louis; Bianco, Michele; Biebel, Otmar; Biedermann, Dustin; Bieniek, Stephen Paul; Biglietti, Michela; Bilbao De Mendizabal, Javier; Bilokon, Halina; Bindi, Marcello; Binet, Sebastien; Bingul, Ahmet; Bini, Cesare; Biondi, Silvia; Black, Curtis; Black, James; Black, Kevin; Blackburn, Daniel; Blair, Robert; Blanchard, Jean-Baptiste; Blanco, Jacobo Ezequiel; Blazek, Tomas; Bloch, Ingo; Blocker, Craig; Blum, Walter; Blumenschein, Ulrike; Bobbink, Gerjan; Bobrovnikov, Victor; Bocchetta, Simona Serena; Bocci, Andrea; Bock, Christopher; Boehler, Michael; Bogaerts, Joannes Andreas; Bogavac, Danijela; Bogdanchikov, Alexander; Bohm, Christian; Boisvert, Veronique; Bold, Tomasz; Boldea, Venera; Boldyrev, Alexey; Bomben, Marco; Bona, Marcella; Boonekamp, Maarten; Borisov, Anatoly; Borissov, Guennadi; Borroni, Sara; Bortfeldt, Jonathan; Bortolotto, Valerio; Bos, Kors; Boscherini, Davide; Bosman, Martine; Boudreau, Joseph; Bouffard, Julian; Bouhova-Thacker, Evelina Vassileva; Boumediene, Djamel Eddine; Bourdarios, Claire; Bousson, Nicolas; Boveia, Antonio; Boyd, James; Boyko, Igor; Bozic, Ivan; Bracinik, Juraj; Brandt, Andrew; Brandt, Gerhard; Brandt, Oleg; Bratzler, Uwe; Brau, Benjamin; Brau, James; Braun, Helmut; Brazzale, Simone Federico; Breaden Madden, William Dmitri; Brendlinger, Kurt; Brennan, Amelia Jean; Brenner, Lydia; Brenner, Richard; Bressler, Shikma; Bristow, Kieran; Bristow, Timothy Michael; Britton, Dave; Britzger, Daniel; Brochu, Frederic; Brock, Ian; Brock, Raymond; Bronner, Johanna; Brooijmans, Gustaaf; Brooks, Timothy; Brooks, William; Brosamer, Jacquelyn; Brost, Elizabeth; Brown, Jonathan; Bruckman de Renstrom, Pawel; Bruncko, Dusan; Bruneliere, Renaud; Bruni, Alessia; Bruni, Graziano; Bruschi, Marco; Bruscino, Nello; Bryngemark, Lene; Buanes, Trygve; Buat, Quentin; Buchholz, Peter; Buckley, Andrew; Buda, Stelian Ioan; Budagov, Ioulian; Buehrer, Felix; Bugge, Lars; Bugge, Magnar Kopangen; Bulekov, Oleg; Bullock, Daniel; Burckhart, Helfried; Burdin, Sergey; Burghgrave, Blake; Burke, Stephen; Burmeister, Ingo; Busato, Emmanuel; Büscher, Daniel; Büscher, Volker; Bussey, Peter; Butler, John; Butt, Aatif Imtiaz; Buttar, Craig; Butterworth, Jonathan; Butti, Pierfrancesco; Buttinger, William; Buzatu, Adrian; Buzykaev, Aleksey; Cabrera Urbán, Susana; Caforio, Davide; Cairo, Valentina; Cakir, Orhan; Calace, Noemi; Calafiura, Paolo; Calandri, Alessandro; Calderini, Giovanni; Calfayan, Philippe; Caloba, Luiz; Calvet, David; Calvet, Samuel; Camacho Toro, Reina; Camarda, Stefano; Camarri, Paolo; Cameron, David; Caminal Armadans, Roger; Campana, Simone; Campanelli, Mario; Campoverde, Angel; Canale, Vincenzo; Canepa, Anadi; Cano Bret, Marc; Cantero, Josu; Cantrill, Robert; Cao, Tingting; Capeans Garrido, Maria Del Mar; Caprini, Irinel; Caprini, Mihai; Capua, Marcella; Caputo, Regina; Cardarelli, Roberto; Cardillo, Fabio; Carli, Tancredi; Carlino, Gianpaolo; Carminati, Leonardo; Caron, Sascha; Carquin, Edson; Carrillo-Montoya, German D; Carter, Janet; Carvalho, João; Casadei, Diego; Casado, Maria Pilar; Casolino, Mirkoantonio; Castaneda-Miranda, Elizabeth; Castelli, Angelantonio; Castillo Gimenez, Victoria; Castro, Nuno Filipe; Catastini, Pierluigi; Catinaccio, Andrea; Catmore, James; Cattai, Ariella; Caudron, Julien; Cavaliere, Viviana; Cavalli, Donatella; Cavalli-Sforza, Matteo; Cavasinni, Vincenzo; Ceradini, Filippo; Cerio, Benjamin; Cerny, Karel; Santiago Cerqueira, Augusto; Cerri, Alessandro; Cerrito, Lucio; Cerutti, Fabio; Cerv, Matevz; Cervelli, Alberto; Cetin, Serkant Ali; Chafaq, Aziz; Chakraborty, Dhiman; Chalupkova, Ina; Chang, Philip; Chapman, John Derek; Charlton, Dave; Chau, Chav Chhiv; Chavez Barajas, Carlos Alberto; Cheatham, Susan; Chegwidden, Andrew; Chekanov, Sergei; Chekulaev, Sergey; Chelkov, Gueorgui; Chelstowska, Magda Anna; Chen, Chunhui; Chen, Hucheng; Chen, Karen; Chen, Liming; Chen, Shenjian; Chen, Xin; Chen, Ye; Cheng, Hok Chuen; Cheng, Yangyang; Cheplakov, Alexander; Cheremushkina, Evgenia; Cherkaoui El Moursli, Rajaa; Chernyatin, Valeriy; Cheu, Elliott; Chevalier, Laurent; Chiarella, Vitaliano; Chiarelli, Giorgio; Childers, John Taylor; Chiodini, Gabriele; Chisholm, Andrew; Chislett, Rebecca Thalatta; Chitan, Adrian; Chizhov, Mihail; Choi, Kyungeon; Chouridou, Sofia; Chow, Bonnie Kar Bo; Christodoulou, Valentinos; Chromek-Burckhart, Doris; Chudoba, Jiri; Chuinard, Annabelle Julia; Chwastowski, Janusz; Chytka, Ladislav; Ciapetti, Guido; Ciftci, Abbas Kenan; Cinca, Diane; Cindro, Vladimir; Cioara, Irina Antonela; Ciocio, Alessandra; Citron, Zvi Hirsh; Ciubancan, Mihai; Clark, Allan G; Clark, Brian Lee; Clark, Philip James; Clarke, Robert; Cleland, Bill; Clement, Christophe; Coadou, Yann; Cobal, Marina; Coccaro, Andrea; Cochran, James H; Coffey, Laurel; Cogan, Joshua Godfrey; Colasurdo, Luca; Cole, Brian; Cole, Stephen; Colijn, Auke-Pieter; Collot, Johann; Colombo, Tommaso; Compostella, Gabriele; Conde Muiño, Patricia; Coniavitis, Elias; Connell, Simon Henry; Connelly, Ian; Consonni, Sofia Maria; Consorti, Valerio; Constantinescu, Serban; Conta, Claudio; Conti, Geraldine; Conventi, Francesco; Cooke, Mark; Cooper, Ben; Cooper-Sarkar, Amanda; Cornelissen, Thijs; Corradi, Massimo; Corriveau, Francois; Corso-Radu, Alina; Cortes-Gonzalez, Arely; Cortiana, Giorgio; Costa, Giuseppe; Costa, María José; Costanzo, Davide; Côté, David; Cottin, Giovanna; Cowan, Glen; Cox, Brian; Cranmer, Kyle; Cree, Graham; Crépé-Renaudin, Sabine; Crescioli, Francesco; Cribbs, Wayne Allen; Crispin Ortuzar, Mireia; Cristinziani, Markus; Croft, Vince; Crosetti, Giovanni; Cuhadar Donszelmann, Tulay; Cummings, Jane; Curatolo, Maria; Cuthbert, Cameron; Czirr, Hendrik; Czodrowski, Patrick; D'Auria, Saverio; D'Onofrio, Monica; Da Cunha Sargedas De Sousa, Mario Jose; Da Via, Cinzia; Dabrowski, Wladyslaw; Dafinca, Alexandru; Dai, Tiesheng; Dale, Orjan; Dallaire, Frederick; Dallapiccola, Carlo; Dam, Mogens; Dandoy, Jeffrey Rogers; Dang, Nguyen Phuong; Daniells, Andrew Christopher; Danninger, Matthias; Dano Hoffmann, Maria; Dao, Valerio; Darbo, Giovanni; Darmora, Smita; Dassoulas, James; Dattagupta, Aparajita; Davey, Will; David, Claire; Davidek, Tomas; Davies, Eleanor; Davies, Merlin; Davison, Peter; Davygora, Yuriy; Dawe, Edmund; Dawson, Ian; Daya-Ishmukhametova, Rozmin; De, Kaushik; de Asmundis, Riccardo; De Benedetti, Abraham; De Castro, Stefano; De Cecco, Sandro; De Groot, Nicolo; de Jong, Paul; De la Torre, Hector; De Lorenzi, Francesco; De Nooij, Lucie; De Pedis, Daniele; De Salvo, Alessandro; De Sanctis, Umberto; De Santo, Antonella; De Vivie De Regie, Jean-Baptiste; Dearnaley, William James; Debbe, Ramiro; Debenedetti, Chiara; Dedovich, Dmitri; Deigaard, Ingrid; Del Peso, Jose; Del Prete, Tarcisio; Delgove, David; Deliot, Frederic; Delitzsch, Chris Malena; Deliyergiyev, Maksym; Dell'Acqua, Andrea; Dell'Asta, Lidia; Dell'Orso, Mauro; Della Pietra, Massimo; della Volpe, Domenico; Delmastro, Marco; Delsart, Pierre-Antoine; Deluca, Carolina; DeMarco, David; Demers, Sarah; Demichev, Mikhail; Demilly, Aurelien; Denisov, Sergey; Derendarz, Dominik; Derkaoui, Jamal Eddine; Derue, Frederic; Dervan, Paul; Desch, Klaus Kurt; Deterre, Cecile; Deviveiros, Pier-Olivier; Dewhurst, Alastair; Dhaliwal, Saminder; Di Ciaccio, Anna; Di Ciaccio, Lucia; Di Domenico, Antonio; Di Donato, Camilla; Di Girolamo, Alessandro; Di Girolamo, Beniamino; Di Mattia, Alessandro; Di Micco, Biagio; Di Nardo, Roberto; Di Simone, Andrea; Di Sipio, Riccardo; Di Valentino, David; Diaconu, Cristinel; Diamond, Miriam; Dias, Flavia; Diaz, Marco Aurelio; Diehl, Edward; Dietrich, Janet; Diglio, Sara; Dimitrievska, Aleksandra; Dingfelder, Jochen; Dita, Petre; Dita, Sanda; Dittus, Fridolin; Djama, Fares; Djobava, Tamar; Djuvsland, Julia Isabell; Barros do Vale, Maria Aline; Dobos, Daniel; Dobre, Monica; Doglioni, Caterina; Dohmae, Takeshi; Dolejsi, Jiri; Dolezal, Zdenek; Dolgoshein, Boris; Donadelli, Marisilvia; Donati, Simone; Dondero, Paolo; Donini, Julien; Dopke, Jens; Doria, Alessandra; Dova, Maria-Teresa; Doyle, Tony; Drechsler, Eric; Dris, Manolis; Dubreuil, Emmanuelle; Duchovni, Ehud; Duckeck, Guenter; Ducu, Otilia Anamaria; Duda, Dominik; Dudarev, Alexey; Duflot, Laurent; Duguid, Liam; Dührssen, Michael; Dunford, Monica; Duran Yildiz, Hatice; Düren, Michael; Durglishvili, Archil; Duschinger, Dirk; Dyndal, Mateusz; Eckardt, Christoph; Ecker, Katharina Maria; Edgar, Ryan Christopher; Edson, William; Edwards, Nicholas Charles; Ehrenfeld, Wolfgang; Eifert, Till; Eigen, Gerald; Einsweiler, Kevin; Ekelof, Tord; El Kacimi, Mohamed; Ellert, Mattias; Elles, Sabine; Ellinghaus, Frank; Elliot, Alison; Ellis, Nicolas; Elmsheuser, Johannes; Elsing, Markus; Emeliyanov, Dmitry; Enari, Yuji; Endner, Oliver Chris; Endo, Masaki; Erdmann, Johannes; Ereditato, Antonio; Ernis, Gunar; Ernst, Jesse; Ernst, Michael; Errede, Steven; Ertel, Eugen; Escalier, Marc; Esch, Hendrik; Escobar, Carlos; Esposito, Bellisario; Etienvre, Anne-Isabelle; Etzion, Erez; Evans, Hal; Ezhilov, Alexey; Fabbri, Laura; Facini, Gabriel; Fakhrutdinov, Rinat; Falciano, Speranza; Falla, Rebecca Jane; Faltova, Jana; Fang, Yaquan; Fanti, Marcello; Farbin, Amir; Farilla, Addolorata; Farooque, Trisha; Farrell, Steven; Farrington, Sinead; Farthouat, Philippe; Fassi, Farida; Fassnacht, Patrick; Fassouliotis, Dimitrios; Faucci Giannelli, Michele; Favareto, Andrea; Fayard, Louis; Federic, Pavol; Fedin, Oleg; Fedorko, Wojciech; Feigl, Simon; Feligioni, Lorenzo; Feng, Cunfeng; Feng, Eric; Feng, Haolu; Fenyuk, Alexander; Feremenga, Last; Fernandez Martinez, Patricia; Fernandez Perez, Sonia; Ferrando, James; Ferrari, Arnaud; Ferrari, Pamela; Ferrari, Roberto; Ferreira de Lima, Danilo Enoque; Ferrer, Antonio; Ferrere, Didier; Ferretti, Claudio; Ferretto Parodi, Andrea; Fiascaris, Maria; Fiedler, Frank; Filipčič, Andrej; Filipuzzi, Marco; Filthaut, Frank; Fincke-Keeler, Margret; Finelli, Kevin Daniel; Fiolhais, Miguel; Fiorini, Luca; Firan, Ana; Fischer, Adam; Fischer, Cora; Fischer, Julia; Fisher, Wade Cameron; Fitzgerald, Eric Andrew; Flaschel, Nils; Fleck, Ivor; Fleischmann, Philipp; Fleischmann, Sebastian; Fletcher, Gareth Thomas; Fletcher, Gregory; Fletcher, Rob Roy MacGregor; Flick, Tobias; Floderus, Anders; Flores Castillo, Luis; Flowerdew, Michael; Formica, Andrea; Forti, Alessandra; Fournier, Daniel; Fox, Harald; Fracchia, Silvia; Francavilla, Paolo; Franchini, Matteo; Francis, David; Franconi, Laura; Franklin, Melissa; Frate, Meghan; Fraternali, Marco; Freeborn, David; French, Sky; Friedrich, Felix; Froidevaux, Daniel; Frost, James; Fukunaga, Chikara; Fullana Torregrosa, Esteban; Fulsom, Bryan Gregory; Fusayasu, Takahiro; Fuster, Juan; Gabaldon, Carolina; Gabizon, Ofir; Gabrielli, Alessandro; Gabrielli, Andrea; Gach, Grzegorz; Gadatsch, Stefan; Gadomski, Szymon; Gagliardi, Guido; Gagnon, Pauline; Galea, Cristina; Galhardo, Bruno; Gallas, Elizabeth; Gallop, Bruce; Gallus, Petr; Galster, Gorm Aske Gram Krohn; Gan, KK; Gao, Jun; Gao, Yanyan; Gao, Yongsheng; Garay Walls, Francisca; Garberson, Ford; García, Carmen; García Navarro, José Enrique; Garcia-Sciveres, Maurice; Gardner, Robert; Garelli, Nicoletta; Garonne, Vincent; Gatti, Claudio; Gaudiello, Andrea; Gaudio, Gabriella; Gaur, Bakul; Gauthier, Lea; Gauzzi, Paolo; Gavrilenko, Igor; Gay, Colin; Gaycken, Goetz; Gazis, Evangelos; Ge, Peng; Gecse, Zoltan; Gee, Norman; Geerts, Daniël Alphonsus Adrianus; Geich-Gimbel, Christoph; Geisler, Manuel Patrice; Gemme, Claudia; Genest, Marie-Hélène; Gentile, Simonetta; George, Matthias; George, Simon; Gerbaudo, Davide; Gershon, Avi; Ghasemi, Sara; Ghazlane, Hamid; Giacobbe, Benedetto; Giagu, Stefano; Giangiobbe, Vincent; Giannetti, Paola; Gibbard, Bruce; Gibson, Stephen; Gilchriese, Murdock; Gillam, Thomas; Gillberg, Dag; Gilles, Geoffrey; Gingrich, Douglas; Giokaris, Nikos; Giordani, MarioPaolo; Giorgi, Filippo Maria; Giorgi, Francesco Michelangelo; Giraud, Pierre-Francois; Giromini, Paolo; Giugni, Danilo; Giuliani, Claudia; Giulini, Maddalena; Gjelsten, Børge Kile; Gkaitatzis, Stamatios; Gkialas, Ioannis; Gkougkousis, Evangelos Leonidas; Gladilin, Leonid; Glasman, Claudia; Glatzer, Julian; Glaysher, Paul; Glazov, Alexandre; Goblirsch-Kolb, Maximilian; Goddard, Jack Robert; Godlewski, Jan; Goldfarb, Steven; Golling, Tobias; Golubkov, Dmitry; Gomes, Agostinho; Gonçalo, Ricardo; Goncalves Pinto Firmino Da Costa, Joao; Gonella, Laura; González de la Hoz, Santiago; Gonzalez Parra, Garoe; Gonzalez-Sevilla, Sergio; Goossens, Luc; Gorbounov, Petr Andreevich; Gordon, Howard; Gorelov, Igor; Gorini, Benedetto; Gorini, Edoardo; Gorišek, Andrej; Gornicki, Edward; Goshaw, Alfred; Gössling, Claus; Gostkin, Mikhail Ivanovitch; Goujdami, Driss; Goussiou, Anna; Govender, Nicolin; Gozani, Eitan; Grabas, Herve Marie Xavier; Graber, Lars; Grabowska-Bold, Iwona; Gradin, Per Olov Joakim; Grafström, Per; Grahn, Karl-Johan; Gramling, Johanna; Gramstad, Eirik; Grancagnolo, Sergio; Grassi, Valerio; Gratchev, Vadim; Gray, Heather; Graziani, Enrico; Greenwood, Zeno Dixon; Gregersen, Kristian; Gregor, Ingrid-Maria; Grenier, Philippe; Griffiths, Justin; Grillo, Alexander; Grimm, Kathryn; Grinstein, Sebastian; Gris, Philippe Luc Yves; Grivaz, Jean-Francois; Grohs, Johannes Philipp; Grohsjean, Alexander; Gross, Eilam; Grosse-Knetter, Joern; Grossi, Giulio Cornelio; Grout, Zara Jane; Guan, Liang; Guenther, Jaroslav; Guescini, Francesco; Guest, Daniel; Gueta, Orel; Guido, Elisa; Guillemin, Thibault; Guindon, Stefan; Gul, Umar; Gumpert, Christian; Guo, Jun; Guo, Yicheng; Gupta, Shaun; Gustavino, Giuliano; Gutierrez, Phillip; Gutierrez Ortiz, Nicolas Gilberto; Gutschow, Christian; Guyot, Claude; Gwenlan, Claire; Gwilliam, Carl; Haas, Andy; Haber, Carl; Hadavand, Haleh Khani; Haddad, Nacim; Haefner, Petra; Hageböck, Stephan; Hajduk, Zbigniew; Hakobyan, Hrachya; Haleem, Mahsana; Haley, Joseph; Hall, David; Halladjian, Garabed; Hallewell, Gregory David; Hamacher, Klaus; Hamal, Petr; Hamano, Kenji; Hamer, Matthias; Hamilton, Andrew; Hamity, Guillermo Nicolas; Hamnett, Phillip George; Han, Liang; Hanagaki, Kazunori; Hanawa, Keita; Hance, Michael; Hanke, Paul; Hanna, Remie; Hansen, Jørgen Beck; Hansen, Jorn Dines; Hansen, Maike Christina; Hansen, Peter Henrik; Hara, Kazuhiko; Hard, Andrew; Harenberg, Torsten; Hariri, Faten; Harkusha, Siarhei; Harrington, Robert; Harrison, Paul Fraser; Hartjes, Fred; Hasegawa, Makoto; Hasegawa, Satoshi; Hasegawa, Yoji; Hasib, A; Hassani, Samira; Haug, Sigve; Hauser, Reiner; Hauswald, Lorenz; Havranek, Miroslav; Hawkes, Christopher; Hawkings, Richard John; Hawkins, Anthony David; Hayashi, Takayasu; Hayden, Daniel; Hays, Chris; Hays, Jonathan Michael; Hayward, Helen; Haywood, Stephen; Head, Simon; Heck, Tobias; Hedberg, Vincent; Heelan, Louise; Heim, Sarah; Heim, Timon; Heinemann, Beate; Heinrich, Lukas; Hejbal, Jiri; Helary, Louis; Hellman, Sten; Hellmich, Dennis; Helsens, Clement; Henderson, James; Henderson, Robert; Heng, Yang; Hengler, Christopher; Henrichs, Anna; Henriques Correia, Ana Maria; Henrot-Versille, Sophie; Herbert, Geoffrey Henry; Hernández Jiménez, Yesenia; Herrberg-Schubert, Ruth; Herten, Gregor; Hertenberger, Ralf; Hervas, Luis; Hesketh, Gavin Grant; Hessey, Nigel; Hetherly, Jeffrey Wayne; Hickling, Robert; Higón-Rodriguez, Emilio; Hill, Ewan; Hill, John; Hiller, Karl Heinz; Hillier, Stephen; Hinchliffe, Ian; Hines, Elizabeth; Hinman, Rachel Reisner; Hirose, Minoru; Hirschbuehl, Dominic; Hobbs, John; Hod, Noam; Hodgkinson, Mark; Hodgson, Paul; Hoecker, Andreas; Hoeferkamp, Martin; Hoenig, Friedrich; Hohlfeld, Marc; Hohn, David; Holmes, Tova Ray; Homann, Michael; Hong, Tae Min; Hooft van Huysduynen, Loek; Hopkins, Walter; Horii, Yasuyuki; Horton, Arthur James; Hostachy, Jean-Yves; Hou, Suen; Hoummada, Abdeslam; Howard, Jacob; Howarth, James; Hrabovsky, Miroslav; Hristova, Ivana; Hrivnac, Julius; Hryn'ova, Tetiana; Hrynevich, Aliaksei; Hsu, Catherine; Hsu, Pai-hsien Jennifer; Hsu, Shih-Chieh; Hu, Diedi; Hu, Qipeng; Hu, Xueye; Huang, Yanping; Hubacek, Zdenek; Hubaut, Fabrice; Huegging, Fabian; Huffman, Todd Brian; Hughes, Emlyn; Hughes, Gareth; Huhtinen, Mika; Hülsing, Tobias Alexander; Huseynov, Nazim; Huston, Joey; Huth, John; Iacobucci, Giuseppe; Iakovidis, Georgios; Ibragimov, Iskander; Iconomidou-Fayard, Lydia; Ideal, Emma; Idrissi, Zineb; Iengo, Paolo; Igonkina, Olga; Iizawa, Tomoya; Ikegami, Yoichi; Ikematsu, Katsumasa; Ikeno, Masahiro; Ilchenko, Iurii; Iliadis, Dimitrios; Ilic, Nikolina; Ince, Tayfun; Introzzi, Gianluca; Ioannou, Pavlos; Iodice, Mauro; Iordanidou, Kalliopi; Ippolito, Valerio; Irles Quiles, Adrian; Isaksson, Charlie; Ishino, Masaya; Ishitsuka, Masaki; Ishmukhametov, Renat; Issever, Cigdem; Istin, Serhat; Iturbe Ponce, Julia Mariana; Iuppa, Roberto; Ivarsson, Jenny; Iwanski, Wieslaw; Iwasaki, Hiroyuki; Izen, Joseph; Izzo, Vincenzo; Jabbar, Samina; Jackson, Brett; Jackson, Matthew; Jackson, Paul; Jaekel, Martin; Jain, Vivek; Jakobs, Karl; Jakobsen, Sune; Jakoubek, Tomas; Jakubek, Jan; Jamin, David Olivier; Jana, Dilip; Jansen, Eric; Jansky, Roland; Janssen, Jens; Janus, Michel; Jarlskog, Göran; Javadov, Namig; Javůrek, Tomáš; Jeanty, Laura; Jejelava, Juansher; Jeng, Geng-yuan; Jennens, David; Jenni, Peter; Jentzsch, Jennifer; Jeske, Carl; Jézéquel, Stéphane; Ji, Haoshuang; Jia, Jiangyong; Jiang, Yi; Jiggins, Stephen; Jimenez Pena, Javier; Jin, Shan; Jinaru, Adam; Jinnouchi, Osamu; Joergensen, Morten Dam; Johansson, Per; Johns, Kenneth; Jon-And, Kerstin; Jones, Graham; Jones, Roger; Jones, Tim; Jongmanns, Jan; Jorge, Pedro; Joshi, Kiran Daniel; Jovicevic, Jelena; Ju, Xiangyang; Jung, Christian; Jussel, Patrick; Juste Rozas, Aurelio; Kaci, Mohammed; Kaczmarska, Anna; Kado, Marumi; Kagan, Harris; Kagan, Michael; Kahn, Sebastien Jonathan; Kajomovitz, Enrique; Kalderon, Charles William; Kama, Sami; Kamenshchikov, Andrey; Kanaya, Naoko; Kaneti, Steven; Kantserov, Vadim; Kanzaki, Junichi; Kaplan, Benjamin; Kaplan, Laser Seymour; Kapliy, Anton; Kar, Deepak; Karakostas, Konstantinos; Karamaoun, Andrew; Karastathis, Nikolaos; Kareem, Mohammad Jawad; Karentzos, Efstathios; Karnevskiy, Mikhail; Karpov, Sergey; Karpova, Zoya; Karthik, Krishnaiyengar; Kartvelishvili, Vakhtang; Karyukhin, Andrey; Kashif, Lashkar; Kass, Richard; Kastanas, Alex; Kataoka, Yousuke; Katre, Akshay; Katzy, Judith; Kawagoe, Kiyotomo; Kawamoto, Tatsuo; Kawamura, Gen; Kazama, Shingo; Kazanin, Vassili; Keeler, Richard; Kehoe, Robert; Keller, John; Kempster, Jacob Julian; Keoshkerian, Houry; Kepka, Oldrich; Kerševan, Borut Paul; Kersten, Susanne; Keyes, Robert; Khalil-zada, Farkhad; Khandanyan, Hovhannes; Khanov, Alexander; Kharlamov, Alexey; Khoo, Teng Jian; Khovanskiy, Valery; Khramov, Evgeniy; Khubua, Jemal; Kim, Hee Yeun; Kim, Hyeon Jin; Kim, Shinhong; Kim, Young-Kee; Kimura, Naoki; Kind, Oliver Maria; King, Barry; King, Matthew; King, Samuel Burton; Kirk, Julie; Kiryunin, Andrey; Kishimoto, Tomoe; Kisielewska, Danuta; Kiss, Florian; Kiuchi, Kenji; Kivernyk, Oleh; Kladiva, Eduard; Klein, Matthew Henry; Klein, Max; Klein, Uta; Kleinknecht, Konrad; Klimek, Pawel; Klimentov, Alexei; Klingenberg, Reiner; Klinger, Joel Alexander; Klioutchnikova, Tatiana; Kluge, Eike-Erik; Kluit, Peter; Kluth, Stefan; Knapik, Joanna; Kneringer, Emmerich; Knoops, Edith; Knue, Andrea; Kobayashi, Aine; Kobayashi, Dai; Kobayashi, Tomio; Kobel, Michael; Kocian, Martin; Kodys, Peter; Koffas, Thomas; Koffeman, Els; Kogan, Lucy Anne; Kohlmann, Simon; Kohout, Zdenek; Kohriki, Takashi; Koi, Tatsumi; Kolanoski, Hermann; Koletsou, Iro; Komar, Aston; Komori, Yuto; Kondo, Takahiko; Kondrashova, Nataliia; Köneke, Karsten; König, Adriaan; Kono, Takanori; Konoplich, Rostislav; Konstantinidis, Nikolaos; Kopeliansky, Revital; Koperny, Stefan; Köpke, Lutz; Kopp, Anna Katharina; Korcyl, Krzysztof; Kordas, Kostantinos; Korn, Andreas; Korol, Aleksandr; Korolkov, Ilya; Korolkova, Elena; Kortner, Oliver; Kortner, Sandra; Kosek, Tomas; Kostyukhin, Vadim; Kotov, Vladislav; Kotwal, Ashutosh; Kourkoumeli-Charalampidi, Athina; Kourkoumelis, Christine; Kouskoura, Vasiliki; Koutsman, Alex; Kowalewski, Robert Victor; Kowalski, Tadeusz; Kozanecki, Witold; Kozhin, Anatoly; Kramarenko, Viktor; Kramberger, Gregor; Krasnopevtsev, Dimitriy; Krasny, Mieczyslaw Witold; Krasznahorkay, Attila; Kraus, Jana; Kravchenko, Anton; Kreiss, Sven; Kretz, Moritz; Kretzschmar, Jan; Kreutzfeldt, Kristof; Krieger, Peter; Krizka, Karol; Kroeninger, Kevin; Kroha, Hubert; Kroll, Joe; Kroseberg, Juergen; Krstic, Jelena; Kruchonak, Uladzimir; Krüger, Hans; Krumnack, Nils; Kruse, Amanda; Kruse, Mark; Kruskal, Michael; Kubota, Takashi; Kucuk, Hilal; Kuday, Sinan; Kuehn, Susanne; Kugel, Andreas; Kuger, Fabian; Kuhl, Andrew; Kuhl, Thorsten; Kukhtin, Victor; Kulchitsky, Yuri; Kuleshov, Sergey; Kuna, Marine; Kunigo, Takuto; Kupco, Alexander; Kurashige, Hisaya; Kurochkin, Yurii; Kus, Vlastimil; Kuwertz, Emma Sian; Kuze, Masahiro; Kvita, Jiri; Kwan, Tony; Kyriazopoulos, Dimitrios; La Rosa, Alessandro; La Rosa Navarro, Jose Luis; La Rotonda, Laura; Lacasta, Carlos; Lacava, Francesco; Lacey, James; Lacker, Heiko; Lacour, Didier; Lacuesta, Vicente Ramón; Ladygin, Evgueni; Lafaye, Remi; Laforge, Bertrand; Lagouri, Theodota; Lai, Stanley; Lambourne, Luke; Lammers, Sabine; Lampen, Caleb; Lampl, Walter; Lançon, Eric; Landgraf, Ulrich; Landon, Murrough; Lang, Valerie Susanne; Lange, J örn Christian; Lankford, Andrew; Lanni, Francesco; Lantzsch, Kerstin; Lanza, Agostino; Laplace, Sandrine; Lapoire, Cecile; Laporte, Jean-Francois; Lari, Tommaso; Lasagni Manghi, Federico; Lassnig, Mario; Laurelli, Paolo; Lavrijsen, Wim; Law, Alexander; Laycock, Paul; Lazovich, Tomo; Le Dortz, Olivier; Le Guirriec, Emmanuel; Le Menedeu, Eve; LeBlanc, Matthew Edgar; LeCompte, Thomas; Ledroit-Guillon, Fabienne Agnes Marie; Lee, Claire Alexandra; Lee, Shih-Chang; Lee, Lawrence; Lefebvre, Guillaume; Lefebvre, Michel; Legger, Federica; Leggett, Charles; Lehan, Allan; Lehmann Miotto, Giovanna; Lei, Xiaowen; Leight, William Axel; Leisos, Antonios; Leister, Andrew Gerard; Leite, Marco Aurelio Lisboa; Leitner, Rupert; Lellouch, Daniel; Lemmer, Boris; Leney, Katharine; Lenz, Tatjana; Lenzi, Bruno; Leone, Robert; Leone, Sandra; Leonidopoulos, Christos; Leontsinis, Stefanos; Lerner, Giuseppe; Leroy, Claude; Lester, Christopher; Levchenko, Mikhail; Levêque, Jessica; Levin, Daniel; Levinson, Lorne; Levy, Mark; Lewis, Adrian; Leyko, Agnieszka; Leyton, Michael; Li, Bing; Li, Haifeng; Li, Ho Ling; Li, Lei; Li, Liang; Li, Shu; Li, Yichen; Liang, Zhijun; Liao, Hongbo; Liberti, Barbara; Liblong, Aaron; Lichard, Peter; Lie, Ki; Liebal, Jessica; Liebig, Wolfgang; Limbach, Christian; Limosani, Antonio; Lin, Simon; Lin, Tai-Hua; Linde, Frank; Lindquist, Brian Edward; Linnemann, James; Lipeles, Elliot; Lipniacka, Anna; Lisovyi, Mykhailo; Liss, Tony; Lissauer, David; Lister, Alison; Litke, Alan; Liu, Bo; Liu, Dong; Liu, Hao; Liu, Jian; Liu, Jianbei; Liu, Kun; Liu, Lulu; Liu, Miaoyuan; Liu, Minghui; Liu, Yanwen; Livan, Michele; Lleres, Annick; Llorente Merino, Javier; Lloyd, Stephen; Lo Sterzo, Francesco; Lobodzinska, Ewelina; Loch, Peter; Lockman, William; Loebinger, Fred; Loevschall-Jensen, Ask Emil; Loginov, Andrey; Lohse, Thomas; Lohwasser, Kristin; Lokajicek, Milos; Long, Brian Alexander; Long, Jonathan David; Long, Robin Eamonn; Looper, Kristina Anne; Lopes, Lourenco; Lopez Mateos, David; Lopez Paredes, Brais; Lopez Paz, Ivan; Lorenz, Jeanette; Lorenzo Martinez, Narei; Losada, Marta; Loscutoff, Peter; Lösel, Philipp Jonathan; Lou, XinChou; Lounis, Abdenour; Love, Jeremy; Love, Peter; Lu, Nan; Lubatti, Henry; Luci, Claudio; Lucotte, Arnaud; Luehring, Frederick; Lukas, Wolfgang; Luminari, Lamberto; Lundberg, Olof; Lund-Jensen, Bengt; Lynn, David; Lysak, Roman; Lytken, Else; Ma, Hong; Ma, Lian Liang; Maccarrone, Giovanni; Macchiolo, Anna; Macdonald, Calum Michael; Machado Miguens, Joana; Macina, Daniela; Madaffari, Daniele; Madar, Romain; Maddocks, Harvey Jonathan; Mader, Wolfgang; Madsen, Alexander; Maeland, Steffen; Maeno, Tadashi; Maevskiy, Artem; Magradze, Erekle; Mahboubi, Kambiz; Mahlstedt, Joern; Maiani, Camilla; Maidantchik, Carmen; Maier, Andreas Alexander; Maier, Thomas; Maio, Amélia; Majewski, Stephanie; Makida, Yasuhiro; Makovec, Nikola; Malaescu, Bogdan; Malecki, Pawel; Maleev, Victor; Malek, Fairouz; Mallik, Usha; Malon, David; Malone, Caitlin; Maltezos, Stavros; Malyshev, Vladimir; Malyukov, Sergei; Mamuzic, Judita; Mancini, Giada; Mandelli, Beatrice; Mandelli, Luciano; Mandić, Igor; Mandrysch, Rocco; Maneira, José; Manfredini, Alessandro; Manhaes de Andrade Filho, Luciano; Manjarres Ramos, Joany; Mann, Alexander; Manning, Peter; Manousakis-Katsikakis, Arkadios; Mansoulie, Bruno; Mantifel, Rodger; Mantoani, Matteo; Mapelli, Livio; March, Luis; Marchiori, Giovanni; Marcisovsky, Michal; Marino, Christopher; Marjanovic, Marija; Marley, Daniel; Marroquim, Fernando; Marsden, Stephen Philip; Marshall, Zach; Marti, Lukas Fritz; Marti-Garcia, Salvador; Martin, Brian Thomas; Martin, Tim; Martin, Victoria Jane; Martin dit Latour, Bertrand; Martinez, Mario; Martin-Haugh, Stewart; Martoiu, Victor Sorin; Martyniuk, Alex; Marx, Marilyn; Marzano, Francesco; Marzin, Antoine; Masetti, Lucia; Mashimo, Tetsuro; Mashinistov, Ruslan; Masik, Jiri; Maslennikov, Alexey; Massa, Ignazio; Massa, Lorenzo; Massol, Nicolas; Mastrandrea, Paolo; Mastroberardino, Anna; Masubuchi, Tatsuya; Mättig, Peter; Mattmann, Johannes; Maurer, Julien; Maxfield, Stephen; Maximov, Dmitriy; Mazini, Rachid; Mazza, Simone Michele; Mazzaferro, Luca; Mc Goldrick, Garrin; Mc Kee, Shawn Patrick; McCarn, Allison; McCarthy, Robert; McCarthy, Tom; McCubbin, Norman; McFarlane, Kenneth; Mcfayden, Josh; Mchedlidze, Gvantsa; McMahon, Steve; McPherson, Robert; Medinnis, Michael; Meehan, Samuel; Mehlhase, Sascha; Mehta, Andrew; Meier, Karlheinz; Meineck, Christian; Meirose, Bernhard; Mellado Garcia, Bruce Rafael; Meloni, Federico; Mengarelli, Alberto; Menke, Sven; Meoni, Evelin; Mercurio, Kevin Michael; Mergelmeyer, Sebastian; Mermod, Philippe; Merola, Leonardo; Meroni, Chiara; Merritt, Frank; Messina, Andrea; Metcalfe, Jessica; Mete, Alaettin Serhan; Meyer, Carsten; Meyer, Christopher; Meyer, Jean-Pierre; Meyer, Jochen; Middleton, Robin; Miglioranzi, Silvia; Mijović, Liza; Mikenberg, Giora; Mikestikova, Marcela; Mikuž, Marko; Milesi, Marco; Milic, Adriana; Miller, David; Mills, Corrinne; Milov, Alexander; Milstead, David; Minaenko, Andrey; Minami, Yuto; Minashvili, Irakli; Mincer, Allen; Mindur, Bartosz; Mineev, Mikhail; Ming, Yao; Mir, Lluisa-Maria; Mitani, Takashi; Mitrevski, Jovan; Mitsou, Vasiliki A; Miucci, Antonio; Miyagawa, Paul; Mjörnmark, Jan-Ulf; Moa, Torbjoern; Mochizuki, Kazuya; Mohapatra, Soumya; Mohr, Wolfgang; Molander, Simon; Moles-Valls, Regina; Mönig, Klaus; Monini, Caterina; Monk, James; Monnier, Emmanuel; Montejo Berlingen, Javier; Monticelli, Fernando; Monzani, Simone; Moore, Roger; Morange, Nicolas; Moreno, Deywis; Moreno Llácer, María; Morettini, Paolo; Morgenstern, Marcus; Mori, Daniel; Morii, Masahiro; Morinaga, Masahiro; Morisbak, Vanja; Moritz, Sebastian; Morley, Anthony Keith; Mornacchi, Giuseppe; Morris, John; Mortensen, Simon Stark; Morton, Alexander; Morvaj, Ljiljana; Mosidze, Maia; Moss, Josh; Motohashi, Kazuki; Mount, Richard; Mountricha, Eleni; Mouraviev, Sergei; Moyse, Edward; Muanza, Steve; Mudd, Richard; Mueller, Felix; Mueller, James; Mueller, Ralph Soeren Peter; Mueller, Thibaut; Muenstermann, Daniel; Mullen, Paul; Mullier, Geoffrey; Murillo Quijada, Javier Alberto; Murray, Bill; Musheghyan, Haykuhi; Musto, Elisa; Myagkov, Alexey; Myska, Miroslav; Nachman, Benjamin Philip; Nackenhorst, Olaf; Nadal, Jordi; Nagai, Koichi; Nagai, Ryo; Nagai, Yoshikazu; Nagano, Kunihiro; Nagarkar, Advait; Nagasaka, Yasushi; Nagata, Kazuki; Nagel, Martin; Nagy, Elemer; Nairz, Armin Michael; Nakahama, Yu; Nakamura, Koji; Nakamura, Tomoaki; Nakano, Itsuo; Namasivayam, Harisankar; Naranjo Garcia, Roger Felipe; Narayan, Rohin; Naumann, Thomas; Navarro, Gabriela; Nayyar, Ruchika; Neal, Homer; Nechaeva, Polina; Neep, Thomas James; Nef, Pascal Daniel; Negri, Andrea; Negrini, Matteo; Nektarijevic, Snezana; Nellist, Clara; Nelson, Andrew; Nemecek, Stanislav; Nemethy, Peter; Nepomuceno, Andre Asevedo; Nessi, Marzio; Neubauer, Mark; Neumann, Manuel; Neves, Ricardo; Nevski, Pavel; Newman, Paul; Nguyen, Duong Hai; Nickerson, Richard; Nicolaidou, Rosy; Nicquevert, Bertrand; Nielsen, Jason; Nikiforou, Nikiforos; Nikiforov, Andriy; Nikolaenko, Vladimir; Nikolic-Audit, Irena; Nikolopoulos, Konstantinos; Nilsen, Jon Kerr; Nilsson, Paul; Ninomiya, Yoichi; Nisati, Aleandro; Nisius, Richard; Nobe, Takuya; Nomachi, Masaharu; Nomidis, Ioannis; Nooney, Tamsin; Norberg, Scarlet; Nordberg, Markus; Novgorodova, Olga; Nowak, Sebastian; Nozaki, Mitsuaki; Nozka, Libor; Ntekas, Konstantinos; Nunes Hanninger, Guilherme; Nunnemann, Thomas; Nurse, Emily; Nuti, Francesco; O'Brien, Brendan Joseph; O'grady, Fionnbarr; O'Neil, Dugan; O'Shea, Val; Oakham, Gerald; Oberlack, Horst; Obermann, Theresa; Ocariz, Jose; Ochi, Atsuhiko; Ochoa, Ines; Ochoa-Ricoux, Juan Pedro; Oda, Susumu; Odaka, Shigeru; Ogren, Harold; Oh, Alexander; Oh, Seog; Ohm, Christian; Ohman, Henrik; Oide, Hideyuki; Okamura, Wataru; Okawa, Hideki; Okumura, Yasuyuki; Okuyama, Toyonobu; Olariu, Albert; Olivares Pino, Sebastian Andres; Oliveira Damazio, Denis; Oliver Garcia, Elena; Olszewski, Andrzej; Olszowska, Jolanta; Onofre, António; Onyisi, Peter; Oram, Christopher; Oreglia, Mark; Oren, Yona; Orestano, Domizia; Orlando, Nicola; Oropeza Barrera, Cristina; Orr, Robert; Osculati, Bianca; Ospanov, Rustem; Otero y Garzon, Gustavo; Otono, Hidetoshi; Ouchrif, Mohamed; Ouellette, Eric; Ould-Saada, Farid; Ouraou, Ahmimed; Oussoren, Koen Pieter; Ouyang, Qun; Ovcharova, Ana; Owen, Mark; Owen, Rhys Edward; Ozcan, Veysi Erkcan; Ozturk, Nurcan; Pachal, Katherine; Pacheco Pages, Andres; Padilla Aranda, Cristobal; Pagáčová, Martina; Pagan Griso, Simone; Paganis, Efstathios; Paige, Frank; Pais, Preema; Pajchel, Katarina; Palacino, Gabriel; Palestini, Sandro; Palka, Marek; Pallin, Dominique; Palma, Alberto; Pan, Yibin; Panagiotopoulou, Evgenia; Pandini, Carlo Enrico; Panduro Vazquez, William; Pani, Priscilla; Panitkin, Sergey; Pantea, Dan; Paolozzi, Lorenzo; Papadopoulou, Theodora; Papageorgiou, Konstantinos; Paramonov, Alexander; Paredes Hernandez, Daniela; Parker, Michael Andrew; Parker, Kerry Ann; Parodi, Fabrizio; Parsons, John; Parzefall, Ulrich; Pasqualucci, Enrico; Passaggio, Stefano; Pastore, Fernanda; Pastore, Francesca; Pásztor, Gabriella; Pataraia, Sophio; Patel, Nikhul; Pater, Joleen; Pauly, Thilo; Pearce, James; Pearson, Benjamin; Pedersen, Lars Egholm; Pedersen, Maiken; Pedraza Lopez, Sebastian; Pedro, Rute; Peleganchuk, Sergey; Pelikan, Daniel; Penc, Ondrej; Peng, Cong; Peng, Haiping; Penning, Bjoern; Penwell, John; Perepelitsa, Dennis; Perez Codina, Estel; Pérez García-Estañ, María Teresa; Perini, Laura; Pernegger, Heinz; Perrella, Sabrina; Peschke, Richard; Peshekhonov, Vladimir; Peters, Krisztian; Peters, Yvonne; Petersen, Brian; Petersen, Troels; Petit, Elisabeth; Petridis, Andreas; Petridou, Chariclia; Petroff, Pierre; Petrolo, Emilio; Petrucci, Fabrizio; Pettersson, Nora Emilia; Pezoa, Raquel; Phillips, Peter William; Piacquadio, Giacinto; Pianori, Elisabetta; Picazio, Attilio; Piccaro, Elisa; Piccinini, Maurizio; Pickering, Mark Andrew; Piegaia, Ricardo; Pignotti, David; Pilcher, James; Pilkington, Andrew; Pina, João Antonio; Pinamonti, Michele; Pinfold, James; Pingel, Almut; Pinto, Belmiro; Pires, Sylvestre; Pirumov, Hayk; Pitt, Michael; Pizio, Caterina; Plazak, Lukas; Pleier, Marc-Andre; Pleskot, Vojtech; Plotnikova, Elena; Plucinski, Pawel; Pluth, Daniel; Poettgen, Ruth; Poggioli, Luc; Pohl, David-leon; Polesello, Giacomo; Poley, Anne-luise; Policicchio, Antonio; Polifka, Richard; Polini, Alessandro; Pollard, Christopher Samuel; Polychronakos, Venetios; Pommès, Kathy; Pontecorvo, Ludovico; Pope, Bernard; Popeneciu, Gabriel Alexandru; Popovic, Dragan; Poppleton, Alan; Pospisil, Stanislav; Potamianos, Karolos; Potrap, Igor; Potter, Christina; Potter, Christopher; Poulard, Gilbert; Poveda, Joaquin; Pozdnyakov, Valery; Pralavorio, Pascal; Pranko, Aliaksandr; Prasad, Srivas; Prell, Soeren; Price, Darren; Price, Lawrence; Primavera, Margherita; Prince, Sebastien; Proissl, Manuel; Prokofiev, Kirill; Prokoshin, Fedor; Protopapadaki, Eftychia-sofia; Protopopescu, Serban; Proudfoot, James; Przybycien, Mariusz; Ptacek, Elizabeth; Puddu, Daniele; Pueschel, Elisa; Puldon, David; Purohit, Milind; Puzo, Patrick; Qian, Jianming; Qin, Gang; Qin, Yang; Quadt, Arnulf; Quarrie, David; Quayle, William; Queitsch-Maitland, Michaela; Quilty, Donnchadha; Raddum, Silje; Radeka, Veljko; Radescu, Voica; Radhakrishnan, Sooraj Krishnan; Radloff, Peter; Rados, Pere; Ragusa, Francesco; Rahal, Ghita; Rajagopalan, Srinivasan; Rammensee, Michael; Rangel-Smith, Camila; Rauscher, Felix; Rave, Stefan; Ravenscroft, Thomas; Raymond, Michel; Read, Alexander Lincoln; Readioff, Nathan Peter; Rebuzzi, Daniela; Redelbach, Andreas; Redlinger, George; Reece, Ryan; Reeves, Kendall; Rehnisch, Laura; Reichert, Joseph; Reisin, Hernan; Relich, Matthew; Rembser, Christoph; Ren, Huan; Renaud, Adrien; Rescigno, Marco; Resconi, Silvia; Rezanova, Olga; Reznicek, Pavel; Rezvani, Reyhaneh; Richter, Robert; Richter, Stefan; Richter-Was, Elzbieta; Ricken, Oliver; Ridel, Melissa; Rieck, Patrick; Riegel, Christian Johann; Rieger, Julia; Rijssenbeek, Michael; Rimoldi, Adele; Rinaldi, Lorenzo; Ristić, Branislav; Ritsch, Elmar; Riu, Imma; Rizatdinova, Flera; Rizvi, Eram; Robertson, Steven; Robichaud-Veronneau, Andree; Robinson, Dave; Robinson, James; Robson, Aidan; Roda, Chiara; Roe, Shaun; Røhne, Ole; Rolli, Simona; Romaniouk, Anatoli; Romano, Marino; Romano Saez, Silvestre Marino; Romero Adam, Elena; Rompotis, Nikolaos; Ronzani, Manfredi; Roos, Lydia; Ros, Eduardo; Rosati, Stefano; Rosbach, Kilian; Rose, Peyton; Rosendahl, Peter Lundgaard; Rosenthal, Oliver; Rossetti, Valerio; Rossi, Elvira; Rossi, Leonardo Paolo; Rosten, Rachel; Rotaru, Marina; Roth, Itamar; Rothberg, Joseph; Rousseau, David; Royon, Christophe; Rozanov, Alexandre; Rozen, Yoram; Ruan, Xifeng; Rubbo, Francesco; Rubinskiy, Igor; Rud, Viacheslav; Rudolph, Christian; Rudolph, Matthew Scott; Rühr, Frederik; Ruiz-Martinez, Aranzazu; Rurikova, Zuzana; Rusakovich, Nikolai; Ruschke, Alexander; Russell, Heather; Rutherfoord, John; Ruthmann, Nils; Ryabov, Yury; Rybar, Martin; Rybkin, Grigori; Ryder, Nick; Saavedra, Aldo; Sabato, Gabriele; Sacerdoti, Sabrina; Saddique, Asif; Sadrozinski, Hartmut; Sadykov, Renat; Safai Tehrani, Francesco; Saimpert, Matthias; Saito, Tomoyuki; Sakamoto, Hiroshi; Sakurai, Yuki; Salamanna, Giuseppe; Salamon, Andrea; Saleem, Muhammad; Salek, David; Sales De Bruin, Pedro Henrique; Salihagic, Denis; Salnikov, Andrei; Salt, José; Salvatore, Daniela; Salvatore, Pasquale Fabrizio; Salvucci, Antonio; Salzburger, Andreas; Sammel, Dirk; Sampsonidis, Dimitrios; Sanchez, Arturo; Sánchez, Javier; Sanchez Martinez, Victoria; Sandaker, Heidi; Sandbach, Ruth Laura; Sander, Heinz Georg; Sanders, Michiel; Sandhoff, Marisa; Sandoval, Carlos; Sandstroem, Rikard; Sankey, Dave; Sannino, Mario; Sansoni, Andrea; Santoni, Claudio; Santonico, Rinaldo; Santos, Helena; Santoyo Castillo, Itzebelt; Sapp, Kevin; Sapronov, Andrey; Saraiva, João; Sarrazin, Bjorn; Sasaki, Osamu; Sasaki, Yuichi; Sato, Koji; Sauvage, Gilles; Sauvan, Emmanuel; Savage, Graham; Savard, Pierre; Sawyer, Craig; Sawyer, Lee; Saxon, James; Sbarra, Carla; Sbrizzi, Antonio; Scanlon, Tim; Scannicchio, Diana; Scarcella, Mark; Scarfone, Valerio; Schaarschmidt, Jana; Schacht, Peter; Schaefer, Douglas; Schaefer, Ralph; Schaeffer, Jan; Schaepe, Steffen; Schaetzel, Sebastian; Schäfer, Uli; Schaffer, Arthur; Schaile, Dorothee; Schamberger, R Dean; Scharf, Veit; Schegelsky, Valery; Scheirich, Daniel; Schernau, Michael; Schiavi, Carlo; Schillo, Christian; Schioppa, Marco; Schlenker, Stefan; Schmidt, Evelyn; Schmieden, Kristof; Schmitt, Christian; Schmitt, Sebastian; Schmitt, Stefan; Schneider, Basil; Schnellbach, Yan Jie; Schnoor, Ulrike; Schoeffel, Laurent; Schoening, Andre; Schoenrock, Bradley Daniel; Schopf, Elisabeth; Schorlemmer, Andre Lukas; Schott, Matthias; Schouten, Doug; Schovancova, Jaroslava; Schramm, Steven; Schreyer, Manuel; Schroeder, Christian; Schuh, Natascha; Schultens, Martin Johannes; Schultz-Coulon, Hans-Christian; Schulz, Holger; Schumacher, Markus; Schumm, Bruce; Schune, Philippe; Schwanenberger, Christian; Schwartzman, Ariel; Schwarz, Thomas Andrew; Schwegler, Philipp; Schweiger, Hansdieter; Schwemling, Philippe; Schwienhorst, Reinhard; Schwindling, Jerome; Schwindt, Thomas; Sciacca, Gianfranco; Scifo, Estelle; Sciolla, Gabriella; Scuri, Fabrizio; Scutti, Federico; Searcy, Jacob; Sedov, George; Sedykh, Evgeny; Seema, Pienpen; Seidel, Sally; Seiden, Abraham; Seifert, Frank; Seixas, José; Sekhniaidze, Givi; Sekhon, Karishma; Sekula, Stephen; Seliverstov, Dmitry; Semprini-Cesari, Nicola; Serfon, Cedric; Serin, Laurent; Serkin, Leonid; Serre, Thomas; Sessa, Marco; Seuster, Rolf; Severini, Horst; Sfiligoj, Tina; Sforza, Federico; Sfyrla, Anna; Shabalina, Elizaveta; Shamim, Mansoora; Shan, Lianyou; Shang, Ruo-yu; Shank, James; Shapiro, Marjorie; Shatalov, Pavel; Shaw, Kate; Shaw, Savanna Marie; Shcherbakova, Anna; Shehu, Ciwake Yusufu; Sherwood, Peter; Shi, Liaoshan; Shimizu, Shima; Shimmin, Chase Owen; Shimojima, Makoto; Shiyakova, Mariya; Shmeleva, Alevtina; Shoaleh Saadi, Diane; Shochet, Mel; Shojaii, Seyedruhollah; Shrestha, Suyog; Shulga, Evgeny; Shupe, Michael; Shushkevich, Stanislav; Sicho, Petr; Sidebo, Per Edvin; Sidiropoulou, Ourania; Sidorov, Dmitri; Sidoti, Antonio; Siegert, Frank; Sijacki, Djordje; Silva, José; Silver, Yiftah; Silverstein, Samuel; Simak, Vladislav; Simard, Olivier; Simic, Ljiljana; Simion, Stefan; Simioni, Eduard; Simmons, Brinick; Simon, Dorian; Simoniello, Rosa; Sinervo, Pekka; Sinev, Nikolai; Sioli, Maximiliano; Siragusa, Giovanni; Sisakyan, Alexei; Sivoklokov, Serguei; Sjölin, Jörgen; Sjursen, Therese; Skinner, Malcolm Bruce; Skottowe, Hugh Philip; Skubic, Patrick; Slater, Mark; Slavicek, Tomas; Slawinska, Magdalena; Sliwa, Krzysztof; Smakhtin, Vladimir; Smart, Ben; Smestad, Lillian; Smirnov, Sergei; Smirnov, Yury; Smirnova, Lidia; Smirnova, Oxana; Smith, Matthew; Smith, Russell; Smizanska, Maria; Smolek, Karel; Snesarev, Andrei; Snidero, Giacomo; Snyder, Scott; Sobie, Randall; Socher, Felix; Soffer, Abner; Soh, Dart-yin; Solans, Carlos; Solar, Michael; Solc, Jaroslav; Soldatov, Evgeny; Soldevila, Urmila; Solodkov, Alexander; Soloshenko, Alexei; Solovyanov, Oleg; Solovyev, Victor; Sommer, Philip; Song, Hong Ye; Soni, Nitesh; Sood, Alexander; Sopczak, Andre; Sopko, Bruno; Sopko, Vit; Sorin, Veronica; Sosa, David; Sosebee, Mark; Sotiropoulou, Calliope Louisa; Soualah, Rachik; Soukharev, Andrey; South, David; Sowden, Benjamin; Spagnolo, Stefania; Spalla, Margherita; Spanò, Francesco; Spearman, William Robert; Sperlich, Dennis; Spettel, Fabian; Spighi, Roberto; Spigo, Giancarlo; Spiller, Laurence Anthony; Spousta, Martin; Spreitzer, Teresa; St Denis, Richard Dante; Staerz, Steffen; Stahlman, Jonathan; Stamen, Rainer; Stamm, Soren; Stanecka, Ewa; Stanescu, Cristian; Stanescu-Bellu, Madalina; Stanitzki, Marcel Michael; Stapnes, Steinar; Starchenko, Evgeny; Stark, Jan; Staroba, Pavel; Starovoitov, Pavel; Staszewski, Rafal; Stavina, Pavel; Steinberg, Peter; Stelzer, Bernd; Stelzer, Harald Joerg; Stelzer-Chilton, Oliver; Stenzel, Hasko; Stewart, Graeme; Stillings, Jan Andre; Stockton, Mark; Stoebe, Michael; Stoicea, Gabriel; Stolte, Philipp; Stonjek, Stefan; Stradling, Alden; Straessner, Arno; Stramaglia, Maria Elena; Strandberg, Jonas; Strandberg, Sara; Strandlie, Are; Strauss, Emanuel; Strauss, Michael; Strizenec, Pavol; Ströhmer, Raimund; Strom, David; Stroynowski, Ryszard; Strubig, Antonia; Stucci, Stefania Antonia; Stugu, Bjarne; Styles, Nicholas Adam; Su, Dong; Su, Jun; Subramaniam, Rajivalochan; Succurro, Antonella; Sugaya, Yorihito; Suhr, Chad; Suk, Michal; Sulin, Vladimir; Sultansoy, Saleh; Sumida, Toshi; Sun, Siyuan; Sun, Xiaohu; Sundermann, Jan Erik; Suruliz, Kerim; Susinno, Giancarlo; Sutton, Mark; Suzuki, Shota; Svatos, Michal; Swedish, Stephen; Swiatlowski, Maximilian; Sykora, Ivan; Sykora, Tomas; Ta, Duc; Taccini, Cecilia; Tackmann, Kerstin; Taenzer, Joe; Taffard, Anyes; Tafirout, Reda; Taiblum, Nimrod; Takai, Helio; Takashima, Ryuichi; Takeda, Hiroshi; Takeshita, Tohru; Takubo, Yosuke; Talby, Mossadek; Talyshev, Alexey; Tam, Jason; Tan, Kong Guan; Tanaka, Junichi; Tanaka, Reisaburo; Tanaka, Shuji; Tannenwald, Benjamin Bordy; Tannoury, Nancy; Tapprogge, Stefan; Tarem, Shlomit; Tarrade, Fabien; Tartarelli, Giuseppe Francesco; Tas, Petr; Tasevsky, Marek; Tashiro, Takuya; Tassi, Enrico; Tavares Delgado, Ademar; Tayalati, Yahya; Taylor, Frank; Taylor, Geoffrey; Taylor, Wendy; Teischinger, Florian Alfred; Teixeira Dias Castanheira, Matilde; Teixeira-Dias, Pedro; Temming, Kim Katrin; Ten Kate, Herman; Teng, Ping-Kun; Teoh, Jia Jian; Tepel, Fabian-Phillipp; Terada, Susumu; Terashi, Koji; Terron, Juan; Terzo, Stefano; Testa, Marianna; Teuscher, Richard; Theveneaux-Pelzer, Timothée; Thomas, Juergen; Thomas-Wilsker, Joshuha; Thompson, Emily; Thompson, Paul; Thompson, Ray; Thompson, Stan; Thomsen, Lotte Ansgaard; Thomson, Evelyn; Thomson, Mark; Thun, Rudolf; Tibbetts, Mark James; Ticse Torres, Royer Edson; Tikhomirov, Vladimir; Tikhonov, Yury; Timoshenko, Sergey; Tiouchichine, Elodie; Tipton, Paul; Tisserant, Sylvain; Todome, Kazuki; Todorov, Theodore; Todorova-Nova, Sharka; Tojo, Junji; Tokár, Stanislav; Tokushuku, Katsuo; Tollefson, Kirsten; Tolley, Emma; Tomlinson, Lee; Tomoto, Makoto; Tompkins, Lauren; Toms, Konstantin; Torrence, Eric; Torres, Heberth; Torró Pastor, Emma; Toth, Jozsef; Touchard, Francois; Tovey, Daniel; Trefzger, Thomas; Tremblet, Louis; Tricoli, Alessandro; Trigger, Isabel Marian; Trincaz-Duvoid, Sophie; Tripiana, Martin; Trischuk, William; Trocmé, Benjamin; Troncon, Clara; Trottier-McDonald, Michel; Trovatelli, Monica; True, Patrick; Truong, Loan; Trzebinski, Maciej; Trzupek, Adam; Tsarouchas, Charilaos; Tseng, Jeffrey; Tsiareshka, Pavel; Tsionou, Dimitra; Tsipolitis, Georgios; Tsirintanis, Nikolaos; Tsiskaridze, Shota; Tsiskaridze, Vakhtang; Tskhadadze, Edisher; Tsukerman, Ilya; Tsulaia, Vakhtang; Tsuno, Soshi; Tsybychev, Dmitri; Tudorache, Alexandra; Tudorache, Valentina; Tuna, Alexander Naip; Tupputi, Salvatore; Turchikhin, Semen; Turecek, Daniel; Turra, Ruggero; Turvey, Andrew John; Tuts, Michael; Tykhonov, Andrii; Tylmad, Maja; Tyndel, Mike; Ueda, Ikuo; Ueno, Ryuichi; Ughetto, Michael; Ugland, Maren; Uhlenbrock, Mathias; Ukegawa, Fumihiko; Unal, Guillaume; Undrus, Alexander; Unel, Gokhan; Ungaro, Francesca; Unno, Yoshinobu; Unverdorben, Christopher; Urban, Jozef; Urquijo, Phillip; Urrejola, Pedro; Usai, Giulio; Usanova, Anna; Vacavant, Laurent; Vacek, Vaclav; Vachon, Brigitte; Valderanis, Chrysostomos; Valencic, Nika; Valentinetti, Sara; Valero, Alberto; Valery, Loic; Valkar, Stefan; Valladolid Gallego, Eva; Vallecorsa, Sofia; Valls Ferrer, Juan Antonio; Van Den Wollenberg, Wouter; Van Der Deijl, Pieter; van der Geer, Rogier; van der Graaf, Harry; Van Der Leeuw, Robin; van Eldik, Niels; van Gemmeren, Peter; Van Nieuwkoop, Jacobus; van Vulpen, Ivo; van Woerden, Marius Cornelis; Vanadia, Marco; Vandelli, Wainer; Vanguri, Rami; Vaniachine, Alexandre; Vannucci, Francois; Vardanyan, Gagik; Vari, Riccardo; Varnes, Erich; Varol, Tulin; Varouchas, Dimitris; Vartapetian, Armen; Varvell, Kevin; Vazeille, Francois; Vazquez Schroeder, Tamara; Veatch, Jason; Veloce, Laurelle Maria; Veloso, Filipe; Velz, Thomas; Veneziano, Stefano; Ventura, Andrea; Ventura, Daniel; Venturi, Manuela; Venturi, Nicola; Venturini, Alessio; Vercesi, Valerio; Verducci, Monica; Verkerke, Wouter; Vermeulen, Jos; Vest, Anja; Vetterli, Michel; Viazlo, Oleksandr; Vichou, Irene; Vickey, Trevor; Vickey Boeriu, Oana Elena; Viehhauser, Georg; Viel, Simon; Vigne, Ralph; Villa, Mauro; Villaplana Perez, Miguel; Vilucchi, Elisabetta; Vincter, Manuella; Vinogradov, Vladimir; Vivarelli, Iacopo; Vives Vaque, Francesc; Vlachos, Sotirios; Vladoiu, Dan; Vlasak, Michal; Vogel, Marcelo; Vokac, Petr; Volpi, Guido; Volpi, Matteo; von der Schmitt, Hans; von Radziewski, Holger; von Toerne, Eckhard; Vorobel, Vit; Vorobev, Konstantin; Vos, Marcel; Voss, Rudiger; Vossebeld, Joost; Vranjes, Nenad; Vranjes Milosavljevic, Marija; Vrba, Vaclav; Vreeswijk, Marcel; Vuillermet, Raphael; Vukotic, Ilija; Vykydal, Zdenek; Wagner, Peter; Wagner, Wolfgang; Wahlberg, Hernan; Wahrmund, Sebastian; Wakabayashi, Jun; Walder, James; Walker, Rodney; Walkowiak, Wolfgang; Wang, Chao; Wang, Fuquan; Wang, Haichen; Wang, Hulin; Wang, Jike; Wang, Jin; Wang, Kuhan; Wang, Rui; Wang, Song-Ming; Wang, Tan; Wang, Tingting; Wang, Xiaoxiao; Wanotayaroj, Chaowaroj; Warburton, Andreas; Ward, Patricia; Wardrope, David Robert; Warsinsky, Markus; Washbrook, Andrew; Wasicki, Christoph; Watkins, Peter; Watson, Alan; Watson, Ian; Watson, Miriam; Watts, Gordon; Watts, Stephen; Waugh, Ben; Webb, Samuel; Weber, Michele; Weber, Stefan Wolf; Webster, Jordan S; Weidberg, Anthony; Weinert, Benjamin; Weingarten, Jens; Weiser, Christian; Weits, Hartger; Wells, Phillippa; Wenaus, Torre; Wengler, Thorsten; Wenig, Siegfried; Wermes, Norbert; Werner, Matthias; Werner, Per; Wessels, Martin; Wetter, Jeffrey; Whalen, Kathleen; Wharton, Andrew Mark; White, Andrew; White, Martin; White, Ryan; White, Sebastian; Whiteson, Daniel; Wickens, Fred; Wiedenmann, Werner; Wielers, Monika; Wienemann, Peter; Wiglesworth, Craig; Wiik-Fuchs, Liv Antje Mari; Wildauer, Andreas; Wilkens, Henric George; Williams, Hugh; Williams, Sarah; Willis, Christopher; Willocq, Stephane; Wilson, Alan; Wilson, John; Wingerter-Seez, Isabelle; Winklmeier, Frank; Winter, Benedict Tobias; Wittgen, Matthias; Wittkowski, Josephine; Wollstadt, Simon Jakob; Wolter, Marcin Wladyslaw; Wolters, Helmut; Wosiek, Barbara; Wotschack, Jorg; Woudstra, Martin; Wozniak, Krzysztof; Wu, Mengqing; Wu, Miles; Wu, Sau Lan; Wu, Xin; Wu, Yusheng; Wyatt, Terry Richard; Wynne, Benjamin; Xella, Stefania; Xu, Da; Xu, Lailin; Yabsley, Bruce; Yacoob, Sahal; Yakabe, Ryota; Yamada, Miho; Yamaguchi, Yohei; Yamamoto, Akira; Yamamoto, Shimpei; Yamanaka, Takashi; Yamauchi, Katsuya; Yamazaki, Yuji; Yan, Zhen; Yang, Haijun; Yang, Hongtao; Yang, Yi; Yao, Weiming; Yasu, Yoshiji; Yatsenko, Elena; Yau Wong, Kaven Henry; Ye, Jingbo; Ye, Shuwei; Yeletskikh, Ivan; Yen, Andy L; Yildirim, Eda; Yorita, Kohei; Yoshida, Rikutaro; Yoshihara, Keisuke; Young, Charles; Young, Christopher John; Youssef, Saul; Yu, David Ren-Hwa; Yu, Jaehoon; Yu, Jiaming; Yu, Jie; Yuan, Li; Yuen, Stephanie P; Yurkewicz, Adam; Yusuff, Imran; Zabinski, Bartlomiej; Zaidan, Remi; Zaitsev, Alexander; Zalieckas, Justas; Zaman, Aungshuman; Zambito, Stefano; Zanello, Lucia; Zanzi, Daniele; Zeitnitz, Christian; Zeman, Martin; Zemla, Andrzej; Zengel, Keith; Zenin, Oleg; Ženiš, Tibor; Zerwas, Dirk; Zhang, Dongliang; Zhang, Fangzhou; Zhang, Huijun; Zhang, Jinlong; Zhang, Lei; Zhang, Ruiqi; Zhang, Xueyao; Zhang, Zhiqing; Zhao, Xiandong; Zhao, Yongke; Zhao, Zhengguo; Zhemchugov, Alexey; Zhong, Jiahang; Zhou, Bing; Zhou, Chen; Zhou, Lei; Zhou, Li; Zhou, Ning; Zhu, Cheng Guang; Zhu, Hongbo; Zhu, Junjie; Zhu, Yingchun; Zhuang, Xuai; Zhukov, Konstantin; Zibell, Andre; Zieminska, Daria; Zimine, Nikolai; Zimmermann, Christoph; Zimmermann, Stephanie; Zinonos, Zinonas; Zinser, Markus; Ziolkowski, Michael; Živković, Lidija; Zobernig, Georg; Zoccoli, Antonio; zur Nedden, Martin; Zurzolo, Giovanni; Zwalinski, Lukasz

    2015-01-01

    This paper reviews and extends searches for the direct pair production of the scalar supersymmetric partners of the top and bottom quarks in proton--proton collisions collected by the ATLAS collaboration during the LHC Run 1. Most of the analyses use 20 fb$^{-1}$ of collisions at a centre-of-mass energy of $\\sqrt{s} = 8$ TeV, although in some case an additional 4.7 fb$^{-1}$ of collision data at $\\sqrt{s}= 7$ TeV are used. New analyses are introduced to improve the sensitivity to specific regions of the model parameter space. Since no evidence of third-generation squarks is found, exclusion limits are derived by combining several analyses and are presented in both a simplified model framework, assuming simple decay chains, as well as within the context of more elaborate phenomenological supersymmetric models.

  18. Large diameter permanent-magnets-expanded plasma source for spontaneous generation of low-energy ion beam.

    Science.gov (United States)

    Takahashi, Kazunori; Suzuki, Tatsuya; Ando, Akira

    2014-02-01

    Diameter of a permanent-magnets-expanded, radiofrequency (rf) plasma source is enlarged up to ∼13 cm for an application to a space propulsion device and tested with being attached to a diffusion chamber. The source is operated at 13.56 MHz 300 W rf power in low-pressure (40 mPa) argon. Measurement of ion energy distribution functions downstream of the source exit shows generation of a supersonic ion beam of about 20 eV. The detailed radial measurements demonstrate that the diameter and energy of the ion beam corresponds to the source tube diameter and the potential difference between the source and downstream plasmas, and that the radial profile of the beam flux is similar to the plasma density profile in the source cavity.

  19. Large capacity, multi-fuel, and high temperature working fluid heaters to optimize CSP plant cost, complexity and annual generation

    Science.gov (United States)

    Peterseim, J. H.; Viscuso, L.; Hellwig, U.; McIntyre, P.

    2016-05-01

    This paper analyses the potential to optimize high temperature fluid back-up systems for concentrating solar power (CSP) plants by investigating the cost impact of component capacity and the impact of using multiple fuels on annual generation. Until now back-up heaters have been limited to 20MWth capacity but larger units have been realised in other industries. Installing larger units yields economy-of-scale benefits through improved manufacturing, optimised transport, and minimized on-site installation work. Halving the number of back-up boilers can yield cost reduction of 23% while minimizing plant complexity and on-site construction risk. However, to achieve these benefits it is important to adapt the back-up heaters to the plant's requirements (load change, capacity, minimum load, etc.) and design for manufacture, transport and assembly. Despite the fact that biomass availability is decreasing with increasing direct normal irradiance (DNI), some biomass is available in areas suitable for CSP plants. The use of these biomass resources is beneficial to maximise annual renewable energy generation, substitute natural gas, and use locally/seasonally available biomass resources that may not be used otherwise. Even small biomass quantities of only 50,000 t/a can increase the capacity factor of a 50MWe parabolic trough plant with 7h thermal energy storage from 40 to 49%. This is a valuable increase and such a concept is suitable for new plants and retrofit applications. However, similar to the capacity optimisation of back-up heaters, various design criteria have to be considered to ensure a successful project.

  20. Generation of uniform large-area very high frequency plasmas by launching two specific standing waves simultaneously

    Science.gov (United States)

    Chen, Hsin-Liang; Tu, Yen-Cheng; Hsieh, Cheng-Chang; Lin, Deng-Lain; Leou, Keh-Chyang

    2014-09-01

    With the characteristics of higher electron density and lower ion bombardment energy, large-area VHF (very high frequency) plasma enhanced chemical vapor deposition has become an essential manufacturing equipment to improve the production throughput and efficiency of thin film silicon solar cell. However, the combination of high frequency and large electrodes leads to the so-called standing wave effect causing a serious problem for the deposition uniformity of silicon thin film. In order to address this issue, a technique based on the idea of simultaneously launching two standing waves that possess similar amplitudes and are out of phase by 90° in time and space is proposed in this study. A linear plasma reactor with discharge length of 54 cm is tested with two different frequencies including 60 and 80 MHz. The experimental results show that the proposed technique could effectively improve the non-uniformity of VHF plasmas from >±60% when only one standing wave is applied to reactor configuration adopted in this study, in which the standing wave effect along the much shorter dimension can be ignored, the proposed technique is applicable to different frequencies without the need to alter the number and arrangement of power feeding points.

  1. Generation of uniform large-area very high frequency plasmas by launching two specific standing waves simultaneously

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Hsin-Liang, E-mail: hlchen@iner.gov.tw; Tu, Yen-Cheng; Hsieh, Cheng-Chang; Lin, Deng-Lain [Physics Division, Institute of Nuclear Energy Research (INER), Longtan, Taoyuan County 32546, Taiwan (China); Leou, Keh-Chyang [Department of Engineering and System Science, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan (China)

    2014-09-14

    With the characteristics of higher electron density and lower ion bombardment energy, large-area VHF (very high frequency) plasma enhanced chemical vapor deposition has become an essential manufacturing equipment to improve the production throughput and efficiency of thin film silicon solar cell. However, the combination of high frequency and large electrodes leads to the so-called standing wave effect causing a serious problem for the deposition uniformity of silicon thin film. In order to address this issue, a technique based on the idea of simultaneously launching two standing waves that possess similar amplitudes and are out of phase by 90° in time and space is proposed in this study. A linear plasma reactor with discharge length of 54 cm is tested with two different frequencies including 60 and 80 MHz. The experimental results show that the proposed technique could effectively improve the non-uniformity of VHF plasmas from >±60% when only one standing wave is applied to <±10% once two specific standing waves are launched at the same time. Moreover, in terms of the reactor configuration adopted in this study, in which the standing wave effect along the much shorter dimension can be ignored, the proposed technique is applicable to different frequencies without the need to alter the number and arrangement of power feeding points.

  2. Laboratory Spectroscopy of Large Carbon Molecules and Ions in Support of Space Missions. A New Generation of Laboratory & Space Studies

    Science.gov (United States)

    Salama, Farid; Tan, Xiaofeng; Cami, Jan; Biennier, Ludovic; Remy, Jerome

    2006-01-01

    Polycyclic Aromatic Hydrocarbons (PAHs) are an important and ubiquitous component of carbon-bearing materials in space. A long-standing and major challenge for laboratory astrophysics has been to measure the spectra of large carbon molecules in laboratory environments that mimic (in a realistic way) the physical conditions that are associated with the interstellar emission and absorption regions [1]. This objective has been identified as one of the critical Laboratory Astrophysics objectives to optimize the data return from space missions [2]. An extensive laboratory program has been developed to assess the properties of PAHs in such environments and to describe how they influence the radiation and energy balance in space. We present and discuss the gas-phase electronic absorption spectra of neutral and ionized PAHs measured in the UV-Visible-NIR range in astrophysically relevant environments and discuss the implications for astrophysics [1]. The harsh physical conditions of the interstellar medium characterized by a low temperature, an absence of collisions and strong VUV radiation fields - have been simulated in the laboratory by associating a pulsed cavity ringdown spectrometer (CRDS) with a supersonic slit jet seeded with PAHs and an ionizing, penning-type, electronic discharge. We have measured for the {\\it first time} the spectra of a series of neutral [3,4] and ionized [5,6] interstellar PAHs analogs in the laboratory. An effort has also been attempted to quantify the mechanisms of ion and carbon nanoparticles production in the free jet expansion and to model our simulation of the diffuse interstellar medium in the laboratory [7]. These experiments provide {\\it unique} information on the spectra of free, large carbon-containing molecules and ions in the gas phase. We are now, for the first time, in the position to directly compare laboratory spectral data on free, cold, PAH ions and carbon nano-sized carbon particles with astronomical observations in the

  3. Development of a large SNP genotyping array and generation of high-density genetic maps in tomato.

    Directory of Open Access Journals (Sweden)

    Sung-Chur Sim

    Full Text Available The concurrent development of high-throughput genotyping platforms and next generation sequencing (NGS has increased the number and density of genetic markers, the efficiency of constructing detailed linkage maps, and our ability to overlay recombination and physical maps of the genome. We developed an array for tomato with 8,784 Single Nucleotide Polymorphisms (SNPs mainly discovered based on NGS-derived transcriptome sequences. Of the SNPs, 7,720 (88% passed manufacturing quality control and could be scored in tomato germplasm. The array was used to generate high-density linkage maps for three interspecific F(2 populations: EXPEN 2000 (Solanum lycopersicum LA0925 x S. pennellii LA0716, 79 individuals, EXPEN 2012 (S. lycopersicum Moneymaker x S. pennellii LA0716, 160 individuals, and EXPIM 2012 (S. lycopersicum Moneymaker x S. pimpinellifolium LA0121, 183 individuals. The EXPEN 2000-SNP and EXPEN 2012 maps consisted of 3,503 and 3,687 markers representing 1,076 and 1,229 unique map positions (genetic bins, respectively. The EXPEN 2000-SNP map had an average marker bin interval of 1.6 cM, while the EXPEN 2012 map had an average bin interval of 0.9 cM. The EXPIM 2012 map was constructed with 4,491 markers (1,358 bins and an average bin interval of 0.8 cM. All three linkage maps revealed an uneven distribution of markers across the genome. The dense EXPEN 2012 and EXPIM 2012 maps showed high levels of colinearity across all 12 chromosomes, and also revealed evidence of small inversions between LA0716 and LA0121. Physical positions of 7,666 SNPs were identified relative to the tomato genome sequence. The genetic and physical positions were mostly consistent. Exceptions were observed for chromosomes 3, 10 and 12. Comparing genetic positions relative to physical positions revealed that genomic regions with high recombination rates were consistent with the known distribution of euchromatin across the 12 chromosomes, while very low recombination rates

  4. Plate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound files.

    Science.gov (United States)

    Bell, Andrew S; Bradley, Joseph; Everett, Jeremy R; Loesel, Jens; McLoughlin, David; Mills, James; Peakman, Marie-Claire; Sharp, Robert E; Williams, Christine; Zhu, Hongyao

    2016-11-01

    High-throughput screening (HTS) is an effective method for lead and probe discovery that is widely used in industry and academia to identify novel chemical matter and to initiate the drug discovery process. However, HTS can be time consuming and costly and the use of subsets as an efficient alternative to screening entire compound collections has been investigated. Subsets may be selected on the basis of chemical diversity, molecular properties, biological activity diversity or biological target focus. Previously, we described a novel form of subset screening: plate-based diversity subset (PBDS) screening, in which the screening subset is constructed by plate selection (rather than individual compound cherry-picking), using algorithms that select for compound quality and chemical diversity on a plate basis. In this paper, we describe a second-generation approach to the construction of an updated subset: PBDS2, using both plate and individual compound selection, that has an improved coverage of the chemical space of the screening file, whilst only selecting the same number of plates for screening. We describe the validation of PBDS2 and its successful use in hit and lead discovery. PBDS2 screening became the default mode of singleton (one compound per well) HTS for lead discovery in Pfizer.

  5. Generation of large-amplitude electric field and subsequent enhancement of O+ ion flux in the inner magnetosphere during substorms

    Science.gov (United States)

    Nakayama, Y.; Ebihara, Y.; Tanaka, T.

    2015-06-01

    Energetic O+ ions are rapidly enhanced in the inner magnetosphere because of abrupt intensification of the dawn-to-dusk electric field and significantly contribute to the ring current during substorms. Here we examine the generation mechanism of the dawn-to-dusk electric field that accelerates the O+ ions and the spatial and temporal evolution of the differential flux of the O+ ions by using a test particle simulation in the electric and magnetic fields that are provided by a global magnetohydrodynamics (MHD) simulation. In the MHD simulation, strong dawn-to-dusk electric field appears in the near-Earth tail region by a joint action of the earthward tension force and pileup of magnetic flux near an onset of substorm expansion. The peak of the electric field is ~9-13 mV/m and is located ~1-2 RE earthward of the peak of the plasma bulk speed because of the pileup. O+ ions coming from the lobe are accelerated from ~eV to >100 keV in ~10 min. The reconstructed flux of the O+ ions shows that at ~7 RE near midnight, the flux has a peak near a few tens of keV and the flux below ~10 keV is small. This structure, called a "void" structure, is consistent with the Polar observation and can be regarded as a manifestation of the acceleration of unmagnetized ions perpendicular to the magnetic field. In the inner magnetosphere (at 6.0 RE), reconstructed energy-time spectrograms show the nose dispersion structure that is also consistent with satellite observations.

  6. The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations.

    Directory of Open Access Journals (Sweden)

    Rodrigo F Oliveira

    Full Text Available Cyclic AMP (cAMP and its main effector Protein Kinase A (PKA are critical for several aspects of neuronal function including synaptic plasticity. Specificity of synaptic plasticity requires that cAMP activates PKA in a highly localized manner despite the speed with which cAMP diffuses. Two mechanisms have been proposed to produce localized elevations in cAMP, known as microdomains: impeded diffusion, and high phosphodiesterase (PDE activity. This paper investigates the mechanism of localized cAMP signaling using a computational model of the biochemical network in the HEK293 cell, which is a subset of pathways involved in PKA-dependent synaptic plasticity. This biochemical network includes cAMP production, PKA activation, and cAMP degradation by PDE activity. The model is implemented in NeuroRD: novel, computationally efficient, stochastic reaction-diffusion software, and is constrained by intracellular cAMP dynamics that were determined experimentally by real-time imaging using an Epac-based FRET sensor (H30. The model reproduces the high concentration cAMP microdomain in the submembrane region, distinct from the lower concentration of cAMP in the cytosol. Simulations further demonstrate that generation of the cAMP microdomain requires a pool of PDE4D anchored in the cytosol and also requires PKA-mediated phosphorylation of PDE4D which increases its activity. The microdomain does not require impeded diffusion of cAMP, confirming that barriers are not required for microdomains. The simulations reported here further demonstrate the utility of the new stochastic reaction-diffusion algorithm for exploring signaling pathways in spatially complex structures such as neurons.

  7. Generation of large-scale intrusions at baroclinic fronts: an analytical consideration with a reference to the Arctic Ocean

    Science.gov (United States)

    Kuzmina, Natalia

    2016-12-01

    Analytical solutions are found for the problem of instability of a weak geostrophic flow with linear velocity shear accounting for vertical diffusion of buoyancy. The analysis is based on the potential-vorticity equation in a long-wave approximation when the horizontal scale of disturbances is considered much larger than the local baroclinic Rossby radius. It is hypothesized that the solutions found can be applied to describe stable and unstable disturbances of the planetary scale with respect, in particular, to the Arctic Ocean, where weak baroclinic fronts with typical temporal variability periods on the order of several years or more have been observed and the β effect is negligible. Stable (decaying with time) solutions describe disturbances that, in contrast to the Rossby waves, can propagate to both the west and east, depending on the sign of the linear shear of geostrophic velocity. The unstable (growing with time) solutions are applied to explain the formation of large-scale intrusions at baroclinic fronts under the stable-stable thermohaline stratification observed in the upper layer of the Polar Deep Water in the Eurasian Basin. The suggested mechanism of formation of intrusions can be considered a possible alternative to the mechanism of interleaving at the baroclinic fronts due to the differential mixing.

  8. Peculiar velocities into the next generation: cosmological parameters from large surveys without bias from non-linear structure

    Science.gov (United States)

    Abate, Alexandra; Bridle, Sarah; Teodoro, Luis F. A.; Warren, Michael S.; Hendry, Martin

    2008-10-01

    We investigate methods to best estimate the normalization of the mass density fluctuation power spectrum (σ8) using peculiar velocity data from a survey like the six-degree Field Galaxy Velocity Survey (6dFGSv). We focus on two potential problems: (i) biases from non-linear growth of structure and (ii) the large number of velocities in the survey. Simulations of ΛCDM-like models are used to test the methods. We calculate the likelihood from a full covariance matrix of velocities averaged in grid cells. This simultaneously reduces the number of data points and smoothes out non-linearities which tend to dominate on small scales. We show how the averaging can be taken into account in the predictions in a practical way, and show the effect of the choice of cell size. We find that a cell size can be chosen that significantly reduces the non-linearities without significantly increasing the error bars on cosmological parameters. We compare our results with those from a principal components analysis following Watkins et al. and Feldman et al. to select a set of optimal moments constructed from linear combinations of the peculiar velocities that are least sensitive to the non-linear scales. We conclude that averaging in grid cells performs equally well. We find that for a survey such as 6dFGSv we can estimate σ8 with less than 3 per cent bias from non-linearities. The expected error on σ8 after marginalizing over Ωm is approximately 16 per cent.

  9. Generation of large-scale, barrier-free diffuse plasmas in air at atmospheric pressure using array wire electrodes and nanosecond high-voltage pulses

    Science.gov (United States)

    Teng, Yun; Li, Lee; Liu, Yun-Long; Liu, Lun; Liu, Minghai

    2014-10-01

    This paper introduces a method to generate large-scale diffuse plasmas by using a repetition nanosecond pulse generator and a parallel array wire-electrode configuration. We investigated barrier-free diffuse plasmas produced in the open air in parallel and cross-parallel array line-line electrode configurations. We found that, when the distance between the wire-electrode pair is small, the discharges were almost extinguished. Also, glow-like diffuse plasmas with little discharge weakening were obtained in an appropriate range of line-line distances and with a cathode-grounding cross-electrode configuration. As an example, we produced a large-scale, stable diffuse plasma with volumes as large as 18 × 15 × 15 cm3, and this discharge region can be further expanded. Additionally, using optical and electrical measurements, we showed that the electron temperature was higher than the gas temperature, which was almost the same as room temperature. Also, an array of electrode configuration with more wire electrodes had helped to prevent the transition from diffuse discharge to arc discharge. Comparing the current waveforms of configurations with 1 cell and 9 cells, we found that adding cells significantly increased the conduction current and the electrical energy delivered in the electrode gaps.

  10. Clinical relevance of sensitive and quantitative STAT3 mutation analysis using next-generation sequencing in T-cell large granular lymphocytic leukemia

    DEFF Research Database (Denmark)

    Kielsgaard Kristensen, Thomas; Larsen, Martin; Rewes, Annika;

    2014-01-01

    Diagnosis of T-cell large granular lymphocytic leukemia (T-LGL) is often challenging because clinical and laboratory characteristics are overlapping with nonneoplastic conditions. Recently, mutation in the STAT3 gene has been identified as a recurrent genetic abnormality in T-LGL. STAT3 mutation......, therefore, represents a promising marker in T-LGL diagnostics. We developed a new quantitative next-generation sequencing assay that allows sensitive analysis of the STAT3 gene. The assay was used to study the utility of STAT3 mutation analysis as a diagnostic tool in T-LGL. The study included 16 T...... donors all tested negative, thus demonstrating the specificity of the assay. The results also indicated that mutation levels in blood and bone marrow are not systematically different, and next-generation sequencing-based STAT3 mutation analysis represents a sensitive method for monitoring residual...

  11. Dynamic model of wind energy conversion systems with variable speed synchronous generator and full-size power converter for large-scale power system stability studies

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, J.A.; Herrero, N.; Wilhelmi, J.R. [Department of Civil Engineering: Hydraulics and Energy, ETSICCP, Universidad Politecnica de Madrid, Ciudad Universitaria, s/n. 28040 Madrid (Spain); Veganzones, C.; Martinez, S.; Blazquez, F. [Department of Electrical Engineering, ETSII, Universidad Politecnica de Madrid, C/Jose Gutierrez Abascal, 2. 28006 Madrid (Spain)

    2008-06-15

    This paper presents a dynamic model for variable speed wind energy conversion systems, equipped with a variable pitch wind turbine, a synchronous electrical generator, and a full power converter, specially developed for its use in power system stability studies involving large networks, with a high number of buses and a high level of wind generation penetration. The validity of the necessary simplifications has been contrasted against a detailed model that allows a thorough insight into the mechanical and electrical behavior of the system, and its interaction with the grid. The developed dynamic model has been implemented in a widely used power system dynamics simulation software, PSS/E, and its performance has been tested in a well-documented test power network. (author)

  12. Distributed fibre optic temperature measurement system for the safety monitoring of the next generation of large nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez Fernandez, Alberto; Brichard, Benoit [SCK-CEN, Belgian Nuclear Research Center (Belgium); Hartog, Arthur H.; Hughes, Paul [SENSA, a Schlumberger Company (United Kingdom)

    2006-07-01

    The use of optical fibre distributed sensors for temperature sensing is a powerful way of monitoring, quasi simultaneously, thousands of points avoiding the requirement of optimum positioning of discrete temperature sensors. Their range of applications is rapidly expanding in the industry, and nowadays this fibre optic sensing technology is mature for industrial applications such as fire detection inside buildings and tunnels, process vessel monitoring, leak detection in cryogenic storage vessels (liquid natural gas (LNG), ammonia, ethylene) or oil wells and the measurement of energy cable thermal distribution for the power supply industry. These applications rely on the well known immunity of fibre optic sensors to electromagnetic interference and the ability of fibre sensors to be operated in hazardous environments. The nuclear industry shows a growing interest for the possibilities offered for temperature sensing applications. Fibre optic sensing technology could be considered as an alternative to classical measurements techniques in a wide range of applications. The potential of distributed temperature measurements for the monitoring of large nuclear infrastructures such as reactor containment buildings, nuclear waste repositories and reactor primary circuitry have already been shown. However, a major problem in the application of optical fibres in nuclear environments is the presence of ionizing radiation fields that induce an increase of the optical fibre attenuation. This radiation-induced degradation of the measurement signal could be critical since most commercially available distributed temperature sensors derive the temperature profile from the measurement of the Raman backscattered light intensity along the fibre, using optical time domain reflectometry techniques. The Raman signal comprises two elements: the Stokes and anti-Stokes lines. The longer wavelength Stokes line is only weakly temperature sensitive but the intensity of the backscattered light

  13. Survey on the technological development issues for large-scale methanol engine power generation plant; Ogata methanol engine hatsuden plant ni kansuru gijutsu kaihatsu kadai chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Based on the result of `Survey on the feasibility of large-scale methanol engine power generation plant` in fiscal 1992, concrete technological development issues were studied for its practical use, and the technological R & D scheme was prepared for large-scale methanol engine power plant featured by low NOx and high efficiency. Technological development issues of this plant were as follows: improvement of thermal efficiency, reduction of NOx emission, improvement of the reliability and durability of ignition and fuel injection systems, and reduction of vibration. As the economical effect of the technological development, the profitability of NOx control measures was compared between this methanol engine and conventional heavy oil diesel engines or gas engines. As a result, this engine was more economical than conventional engines. It was suggested that development of the equipment will be completed in nearly 4 years through every component study, single-cylinder model experiment and real engine test. 21 refs., 43 figs., 19 tabs.

  14. Large-scale experimental facility for emergency condition investigation of a new generation NPP WWER-640 reactor with passive safety systems

    Energy Technology Data Exchange (ETDEWEB)

    Aniskevich, Y.N.; Vasilenko, V.A.; Zasukha, V.K.; Migrov, Y.A.; Khabensky, V.B. [Research Inst. of Technology NITI (Russian Federation)

    1997-12-31

    The creation of the large-scale integral experimental facility (KMS) is specified by the programme of the experimental investigations to justify the engineering decisions on the safety of the design of the new generation NPP with the reactor WWER-640. The construction of KMS in a full volume will allow to conduct experimental investigations of all physical phenomena and processes, practically, occurring during the accidents on the NPPs with the reactor of WWER type and including the heat - mass exchange processes with low rates of the coolant, which is typical during the utilization of the passive safety systems, process during the accidents with a large leak, and also the complex intercommunicated processes in the reactor unit, passive safety systems and in the containment with the condition of long-term heat removal to the final absorber. KMS is being constructed at the Research Institute of Technology (NITI), Sosnovy Bor, Leningrad region, Russia. (orig.). 5 refs.

  15. Investigation of the effect of the structure of large-area carbon nanotube/fuel composites on energy generation from thermopower waves.

    Science.gov (United States)

    Hwang, Hayoung; Yeo, Taehan; Um, Jo-Eun; Lee, Kang Yeol; Kim, Hong-Seok; Han, Jae-Hee; Kim, Woo-Jae; Choi, Wonjoon

    2014-01-01

    Thermopower waves are a recently developed energy conversion concept utilizing dynamic temperature and chemical potential gradients to harvest electrical energy while the combustion wave propagates along the hybrid layers of nanomaterials and chemical fuels. The intrinsic properties of the core nanomaterials and chemical fuels in the hybrid composites can broadly affect the energy generation, as well as the combustion process, of thermopower waves. So far, most research has focused on the application of new core nanomaterials to enhance energy generation. In this study, we demonstrate that the alignment of core nanomaterials can significantly influence a number of aspects of the thermopower waves, while the nanomaterials involved are identical carbon nanotubes (CNTs). Diversely structured, large-area CNT/fuel composites of one-dimensional aligned CNT arrays (1D CNT arrays), randomly oriented CNT films (2D CNT films), and randomly aggregated bulk CNT clusters (3D CNT clusters) were fabricated to evaluate the energy generation, as well as the propagation of the thermal wave, from thermopower waves. The more the core nanostructures were aligned, the less inversion of temperature gradients and the less cross-propagation of multiple thermopower waves occurred. These characteristics of the aligned structures prevented the cancellation of charge carrier movements among the core nanomaterials and produced the relative enhancement of the energy generation and the specific power with a single-polarity voltage signal. Understanding this effect of structure on energy generation from thermopower waves can help in the design of optimized hybrid composites of nanomaterials and fuels, especially designs based on the internal alignment of the materials. More generally, we believe that this work provides clues to the process of chemical to thermal to electrical energy conversion inside/outside hybrid nanostructured materials.

  16. APPLICATION OF VISION METROLOGY TO IN-ORBIT MEASUREMENT OF LARGE REFLECTOR ONBOARD COMMUNICATION SATELLITE FOR NEXT GENERATION MOBILE SATELLITE COMMUNICATION

    Directory of Open Access Journals (Sweden)

    M. Akioka

    2016-06-01

    Full Text Available Satellite for next generation mobile satellite communication service with small personal terminal requires onboard antenna with very large aperture reflector larger than twenty meters diameter because small personal terminal with lower power consumption in ground base requires the large onboard reflector with high antenna gain. But, large deployable antenna will deform in orbit because the antenna is not a solid dish but the flexible structure with fine cable and mesh supported by truss. Deformation of reflector shape deteriorate the antenna performance and quality and stability of communication service. However, in case of digital beam forming antenna with phased array can modify the antenna beam performance due to adjustment of excitation amplitude and excitation phase. If we can measure the reflector shape precisely in orbit, beam pattern and antenna performance can be compensated with the updated excitation amplitude and excitation phase parameters optimized for the reflector shape measured every moment. Softbank Corporation and National Institute of Information and Communications Technology has started the project "R&D on dynamic beam control technique for next generation mobile communication satellite" as a contracted research project sponsored by Ministry of Internal Affairs and Communication of Japan. In this topic, one of the problem in vision metrology application is a strong constraints on geometry for camera arrangement on satellite bus with very limited space. On satellite in orbit, we cannot take many images from many different directions as ordinary vision metrology measurement and the available area for camera positioning is quite limited. Feasibility of vision metrology application and general methodology to apply to future mobile satellite communication satellite is to be found. Our approach is as follows: 1 Development of prototyping simulator to evaluate the expected precision for network design in zero order and first order

  17. Application of Vision Metrology to In-Orbit Measurement of Large Reflector Onboard Communication Satellite for Next Generation Mobile Satellite Communication

    Science.gov (United States)

    Akioka, M.; Orikasa, T.; Satoh, M.; Miura, A.; Tsuji, H.; Toyoshima, M.; Fujino, Y.

    2016-06-01

    Satellite for next generation mobile satellite communication service with small personal terminal requires onboard antenna with very large aperture reflector larger than twenty meters diameter because small personal terminal with lower power consumption in ground base requires the large onboard reflector with high antenna gain. But, large deployable antenna will deform in orbit because the antenna is not a solid dish but the flexible structure with fine cable and mesh supported by truss. Deformation of reflector shape deteriorate the antenna performance and quality and stability of communication service. However, in case of digital beam forming antenna with phased array can modify the antenna beam performance due to adjustment of excitation amplitude and excitation phase. If we can measure the reflector shape precisely in orbit, beam pattern and antenna performance can be compensated with the updated excitation amplitude and excitation phase parameters optimized for the reflector shape measured every moment. Softbank Corporation and National Institute of Information and Communications Technology has started the project "R&D on dynamic beam control technique for next generation mobile communication satellite" as a contracted research project sponsored by Ministry of Internal Affairs and Communication of Japan. In this topic, one of the problem in vision metrology application is a strong constraints on geometry for camera arrangement on satellite bus with very limited space. On satellite in orbit, we cannot take many images from many different directions as ordinary vision metrology measurement and the available area for camera positioning is quite limited. Feasibility of vision metrology application and general methodology to apply to future mobile satellite communication satellite is to be found. Our approach is as follows: 1) Development of prototyping simulator to evaluate the expected precision for network design in zero order and first order 2) Trial

  18. 大型发电机定子线圈绝缘结构试验研究%Insulation System Testing Research for Stator Coils of Large Generator

    Institute of Scientific and Technical Information of China (English)

    潘延明; 陈阳

    2016-01-01

    Insulation diagnosis test equipment selecting and test procedure are detailed introduced for stator coils of large generator. Based on the domestic standard and overseas standard, evaluation test for electric stress, electric combined with thermal stress, environment stress, thermo-mechanical stress and electric-mechanical stress are performed for stator coils of large generator. Strict diagnosis test and evaluation test provide reliable quality assurance for failure-free operating of stator winding.%本文详述了大型发电机定子线圈绝缘结构试验的设备选取原则和试验程序;结合国内外标准,对定子线圈绝缘结构开展电应力、电热应力、环境应力、热机械应力、电机械应力评定试验。严格的诊断与评定为定子绕组的正常运行提供可靠的质量保证。

  19. Comment on ``Neutrino oscillations in the early universe: how can large lepton asymmetry be generated?'' [Astropart. Phys. 14 (2000) 79-90

    Science.gov (United States)

    Di Bari, P.; Foot, R.; Volkas, R. R.; Wong, Y. Y. Y.

    2001-08-01

    We comment on the recent paper by A.D. Dolgov, S.H. Hansen, S. Pastor and D.V. Semikoz (DHPS) [Astropart. Phys. 14 (2000) 79] on the generation of neutrino asymmetries from active-sterile neutrino oscillations. We demonstrate that the approximate asymmetry evolution equation obtained therein is an expansion, up to a minor discrepancy, of the well-established static approximation equation, valid only when the supposedly new higher order correction term is small. In the regime where this so-called "back-reaction" term is large and artificially terminates the asymmetry growth, their evolution equation ceases to be a faithful approximation to the quantum kinetic equations simply because pure Mikheyev-Smirnov-Wolfenstein (MSW) transitions have been neglected. At low temperatures the MSW effect is the dominant asymmetry amplifier. Neither the static nor the DHPS approach contains this important physics. Therefore we conclude that the DHPS results have sufficient veracity at the onset of explosive asymmetry generation, but are invalid in the ensuing low temperature epoch where MSW conversions are able to enhance the asymmetry to values of order 0.2-0.37. DHPS do claim to find a significant final asymmetry for very large δm2 values. However, for this regime the effective potential they employed is not valid.

  20. Stochastic analysis and simulation of large dimensional intermittent fields with the help of a Lévy-Clifford algebra of multifractal cascade generators.

    Science.gov (United States)

    Schertzer, Daniel; Tchiguirinskaia, Ioula

    2017-04-01

    Multifractal fields have opened a new approach in geophysics to explore "spatial chaos", i.e. processes that are not only complex in time but also in space, because their definition is rather independent of their domain dimension. However multifractals have been for too long restricted to be scalar valued, i.e. to have one-dimensional codomains. This has prevented to deal with the key question of complex component interactions of vector fields and their non trivial symmetries. On the theoretical level, this is resolved by considering the Lie algebra of stochastic generators of cascade processes with arbitrarily large codomains, e.g. flows of vector fields over large dimensional manifolds. We recently investigated the neat example of stable Levy generators on Clifford algebra that provide both universal statistical and robust algebraic properties to the basic symmetries of the corresponding fields (Schertzer and Tchiguirinskaia, 2015). This presentation will focus on the concrete analysis of observation data and their simulation in the Levy-Clifford algebra framework. This correspond to a wide and innovative generalisation of classical multifractal methodologies. Schertzer, D. & Tchiguirinskaia, I., 2015. Multifractal vector fields and stochastic Clifford algebra. Chaos: An Interdisciplinary Journal of Nonlinear Science, 25(12), p.123127.

  1. Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines.

    Directory of Open Access Journals (Sweden)

    Azhar R Hussain

    Full Text Available BACKGROUND: We have recently shown that deregulation PI3-kinase/AKT survival pathway plays an important role in pathogenesis of diffuse large B cell lymphoma (DLBCL. In an attempt to identify newer therapeutic agents, we investigated the role of Resveratrol (trans-3,4', 5-trihydroxystilbene, a naturally occurring polyphenolic compound on a panel of diffuse large B-cell lymphoma (DLBCL cells in causing inhibition of cell viability and inducing apoptosis. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the action of Resveratrol on DLBCL cells and found that Resveratrol inhibited cell viability and induced apoptosis by inhibition of constitutively activated AKT and its downstream targets via generation of reactive oxygen species (ROS. Simultaneously, Resveratrol treatment of DLBCL cell lines also caused ROS dependent upregulation of DR5; and interestingly, co-treatment of DLBCL with sub-toxic doses of TRAIL and Resveratrol synergistically induced apoptosis via utilizing DR5, on the other hand, gene silencing of DR5 abolished this effect. CONCLUSION/SIGNIFICANCE: Altogether, these data suggest that Resveratrol acts as a suppressor of AKT/PKB pathway leading to apoptosis via generation of ROS and at the same time primes DLBCL cells via up-regulation of DR5 to TRAIL-mediated apoptosis. These data raise the possibility that Resveratrol may have a future therapeutic role in DLBCL and possibly other malignancies with constitutive activation of the AKT/PKB pathway.

  2. The Primordial Magnetic Field (PMF) Generated in Large Field Inflation (LFI), Natural Inflation (NI) and $R^2$-Inflation by $f^{2}FF$ Model

    CERN Document Server

    AlMuhammad, Anwar Saleh

    2016-01-01

    Large scale magnetic fields seem to be present in almost all astrophysical systems and scales from planets to superclusters of galaxies and in very low density intergalactic media. The upper limit of primordial magnetic fields (PMF) has been set by recent observations by the Planck observatory (2015) to be of the order of a few nG. The simple model ${f^2}FF$ used to generate the PMF during the inflation era. It is based on the breaking of conformal symmetry of electromagnetism during inflation. It is attractive because it is stable under perturbations and leads to a scale invariant PMF. However, it may suffer from two problems: Backreaction and strong coupling. In the first case, the electromagnetic energy may exceed the energy of inflation, ${\\rho _{{\\rm{Inf}}}}$. In the second case, the effective electric charges become excessively large if we want to retrieve the standard electromagnetism at the end of inflation. In this research, we investigate the generation of PMF under three different models of inflati...

  3. Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens.

    Science.gov (United States)

    Smith, Cynthia L; Eppig, Janan T

    2015-01-01

    A vast array of data is about to emerge from the large scale high-throughput mouse knockout phenotyping projects worldwide. It is critical that this information is captured in a standardized manner, made accessible, and is fully integrated with other phenotype data sets for comprehensive querying and analysis across all phenotype data types. The volume of data generated by the high-throughput phenotyping screens is expected to grow exponentially, thus, automated methods and standards to exchange phenotype data are required. The IMPC (International Mouse Phenotyping Consortium) is using the Mammalian Phenotype (MP) ontology in the automated annotation of phenodeviant data from high throughput phenotyping screens. 287 new term additions with additional hierarchy revisions were made in multiple branches of the MP ontology to accurately describe the results generated by these high throughput screens. Because these large scale phenotyping data sets will be reported using the MP as the common data standard for annotation and data exchange, automated importation of these data to MGI (Mouse Genome Informatics) and other resources is possible without curatorial effort. Maximum biomedical value of these mutant mice will come from integrating primary high-throughput phenotyping data with secondary, comprehensive phenotypic analyses combined with published phenotype details on these and related mutants at MGI and other resources.

  4. High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery.

    Science.gov (United States)

    Turchetto, Jeremy; Sequeira, Ana Filipa; Ramond, Laurie; Peysson, Fanny; Brás, Joana L A; Saez, Natalie J; Duhoo, Yoan; Blémont, Marilyne; Guerreiro, Catarina I P D; Quinton, Loic; De Pauw, Edwin; Gilles, Nicolas; Darbon, Hervé; Fontes, Carlos M G A; Vincentelli, Renaud

    2017-01-17

    Animal venoms are complex molecular cocktails containing a wide range of biologically active disulphide-reticulated peptides that target, with high selectivity and efficacy, a variety of membrane receptors. Disulphide-reticulated peptides have evolved to display improved specificity, low immunogenicity and to show much higher resistance to degradation than linear peptides. These properties make venom peptides attractive candidates for drug development. However, recombinant expression of reticulated peptides containing disulphide bonds is challenging, especially when associated with the production of large libraries of bioactive molecules for drug screening. To date, as an alternative to artificial synthetic chemical libraries, no comprehensive recombinant libraries of natural venom peptides are accessible for high-throughput screening to identify novel therapeutics. In the accompanying paper an efficient system for the expression and purification of oxidized disulphide-reticulated venom peptides in Escherichia coli is described. Here we report the development of a high-throughput automated platform, that could be adapted to the production of other families, to generate the largest ever library of recombinant venom peptides. The peptides were produced in the periplasm of E. coli using redox-active DsbC as a fusion tag, thus allowing the efficient formation of correctly folded disulphide bridges. TEV protease was used to remove fusion tags and recover the animal venom peptides in the native state. Globally, within nine months, out of a total of 4992 synthetic genes encoding a representative diversity of venom peptides, a library containing 2736 recombinant disulphide-reticulated peptides was generated. The data revealed that the animal venom peptides produced in the bacterial host were natively folded and, thus, are putatively biologically active. Overall this study reveals that high-throughput expression of animal venom peptides in E. coli can generate large

  5. Next Generation Very Large Array Memo No. 7 Science Working Group 2: "Galaxy Ecosystems": The Matter Cycle in and Around Galaxies

    CERN Document Server

    Leroy, Adam K; Armus, Lee; Brogan, Crystal; Meyer, Jennifer Donovan; Evans, Aaron; Hunter, Todd; Johnson, Kelsey; Koda, Jin; Meier, David S; Menten, Karl; Mills, Elizabeth; Momjian, Emmanuel; Ott, Juergen; Owen, Frazer; Reid, Mark; Rosolowsky, Erik; Schinnerer, Eva; Scoville, Nicholas; Spekkens, Kristine; van Zee, Liese; Wong, Tony

    2015-01-01

    This white paper discusses how a "next-generation" Very Large Array (ngVLA) operating in the frequency range 1-116 GHz could be a groundbreaking tool to study the detailed astrophysics of the "matter cycle" in the Milky Way and other galaxies. If optimized for high brightness sensitivity, the ngVLA would bring detailed microwave spectroscopy and modeling of the full radio spectral energy distribution into regular use as survey tools at resolutions of 0.1- 1 arcseconds. This wavelength range includes powerful diagnostics of density, excitation, and chemistry in the cold ISM, as well as multiple tracers of the rate of recent star formation, the magnetic field, shocks, and properties of the ionized ISM. We highlight design considerations that would make this facility revolutionary in this area, the foremost of which is a large amount of collecting area on ~km-length baselines. We also emphasize the strong case for harnessing the large proposed collecting area of the ngVLA for very long baseline applications as p...

  6. scaling theory of floods for predictions in a changing climate: a model to generate ensembles of runoff from a large number of hillslopes (Invited)

    Science.gov (United States)

    Furey, P.; Gupta, V. K.; Troutman, B. M.

    2013-12-01

    Peak flows in individual rainfall-runoff events exhibit spatial scaling in the 21 km2 Goodwin Creek Experimental Watershed (GCEW) in Mississippi, USA. A nonlinear geophysical theory has been developing to understand how scaling in peak flows for Rainfall-Runoff events arises from solutions of mass and momentum conservation equations in channel networks with self-similar topologies and geometries. The conservation equations are specified at the natural hillslope-link scale. The central hypothesis of the theory is that scaling is an emergent property in the limit of large drainage area. To develop a physical understanding of scaling, runoff generation from each hillslope in the basin is needed. GCEW contains 544 hillslopes, and direct observations of infiltration only exist, at best, at few locations. This situation is typical of all river basins in the world. As a result, representing the spatial and temporal variability of runoff generation throughout any river basin presents a great scientific challenge. Most models use point-scale equations for infiltration and point-scale observations to represent runoff generation at a larger scale, e.g. hillslope scale. We develop a physical-statistical hypothesis, combining both top-down and bottom-up observations, that hillslope water loss is inversely related to a function of a lognormal random variable. We take a top-down approach to develop a new runoff generation model to test our hypothesis. The model is based on the assumption that the probability distributions of a runoff-loss ratio have a space-time rescaling property. For over 100 rainfall-runoff events in GCEW, we found that the spatial probability distributions of a runoff-loss ratio can be rescaled to a new distribution that is common to all events. We interpret that random within-event differences in runoff-loss ratios in the model arise due to soil moisture spatial variability of water loss during events that is supported by observations. As an application of

  7. Generating pseudo large footprint waveforms from small footprint full-waveform airborne LiDAR data for the layered retrieval of LAI in orchards.

    Science.gov (United States)

    Li, Wang; Niu, Zheng; Li, Jing; Chen, Hanyue; Gao, Shuai; Wu, Mingquan; Li, Dong

    2016-05-02

    Leaf area index (LAI) is a key parameter for the study of biogeochemical cycles in ecosystems. Remote sensing techniques have been widely used to estimate LAIs in a wide range of vegetation types. However, limited by the sensor detection capability, considerable fewer studies investigated the layered estimation of LAIs in the vertical direction, which can significantly affect the precision evaluation of vegetation biophysical and biochemical processes. This study tried to generate a kind of pseudo large footprint waveform from the small footprint full-waveform airborne LiDAR data by an aggregation approach. The layered distribution of canopy heights and LAIs were successfully retrieved based on the large footprint waveform data in an agricultural landscape of orchards with typical multi-layer vegetation covers. The Gaussian fitting was conducted on the normalized large footprint waveforms to identify the vertical positions for different vegetation layers. Then, the gap theory was applied to retrieve the layered LAIs. Statistically significant simple linear regression models were fitted between the LiDAR-retrieved and field-observed values for the canopy heights and LAIs in different layers. Satisfactory results were obtained with a root mean square error of 0.36 m for the overstorey canopy height (R2 = 0.82), 0.29 m for the understory canopy height (R2 = 0.76), 0.28 for overstorey LAI (R2 = 0.75), 0.40 for understory LAI (R2 = 0.64), and 0.38 for total LAI (R2 = 0.69), respectively. To conclude, estimating the layered LAIs in the multi-layer agriculture orchards from the pseudo large footprint waveforms is feasible and the estimation errors are acceptable, which will provide some new ideas and methods for the quantitative remote sensing with vegetation.

  8. Annotation-based genome-wide SNP discovery in the large and complex Aegilops tauschii genome using next-generation sequencing without a reference genome sequence

    Directory of Open Access Journals (Sweden)

    Luo Ming-Cheng

    2011-01-01

    Full Text Available Abstract Background Many plants have large and complex genomes with an abundance of repeated sequences. Many plants are also polyploid. Both of these attributes typify the genome architecture in the tribe Triticeae, whose members include economically important wheat, rye and barley. Large genome sizes, an abundance of repeated sequences, and polyploidy present challenges to genome-wide SNP discovery using next-generation sequencing (NGS of total genomic DNA by making alignment and clustering of short reads generated by the NGS platforms difficult, particularly in the absence of a reference genome sequence. Results An annotation-based, genome-wide SNP discovery pipeline is reported using NGS data for large and complex genomes without a reference genome sequence. Roche 454 shotgun reads with low genome coverage of one genotype are annotated in order to distinguish single-copy sequences and repeat junctions from repetitive sequences and sequences shared by paralogous genes. Multiple genome equivalents of shotgun reads of another genotype generated with SOLiD or Solexa are then mapped to the annotated Roche 454 reads to identify putative SNPs. A pipeline program package, AGSNP, was developed and used for genome-wide SNP discovery in Aegilops tauschii-the diploid source of the wheat D genome, and with a genome size of 4.02 Gb, of which 90% is repetitive sequences. Genomic DNA of Ae. tauschii accession AL8/78 was sequenced with the Roche 454 NGS platform. Genomic DNA and cDNA of Ae. tauschii accession AS75 was sequenced primarily with SOLiD, although some Solexa and Roche 454 genomic sequences were also generated. A total of 195,631 putative SNPs were discovered in gene sequences, 155,580 putative SNPs were discovered in uncharacterized single-copy regions, and another 145,907 putative SNPs were discovered in repeat junctions. These SNPs were dispersed across the entire Ae. tauschii genome. To assess the false positive SNP discovery rate, DNA

  9. The role of next-generation sequencing in understanding the genomic basis of diffuse large B cell lymphoma and advancing targeted therapies.

    Science.gov (United States)

    Dubois, Sydney; Jardin, Fabrice

    2016-03-01

    Next Generation Sequencing (NGS) has redefined the genetic landscape of Diffuse Large B-Cell Lymphoma (DLBCL) by identifying recurrent somatic mutations. Importantly, in some cases these mutations impact potentially actionable targets, thus affording novel personalized therapy opportunities. At the forefront of today's precision therapy era, how to best incorporate NGS into daily clinical practice is of primordial concern, in order to tailor patient's treatment regimens according to their individual mutational profiles. With the advent of cell-free DNA sequencing, which provides a sensitive and less invasive means of monitoring DLBCL patients, the clinical feasibility of NGS has been greatly improved. This article reviews the current landscape of DLBCL mutations, as well as the targeted therapies developed to counter their effects, and discusses how best to utilize NGS data for treatment decision-making.

  10. Generating functional and large N limit of nonlocal 2D generalized Yang-Mills theories (nlgYM{sub 2}'s)

    Energy Technology Data Exchange (ETDEWEB)

    Saaidi, K.; Sajadi, H.M. [Dept. of Physics, Univ. of Tehran (Iran)

    2001-01-01

    Using the path integral method, we calculate the partition function and the generating functional (of the field strengths) on nonlocal generalized 2D Yang-Mills theories (nlgYM{sub 2}'s), which are nonlocal in the auxiliary field. This has been considered before by Saaidi and Khorrami. Our calculations are done for general surfaces. We find a general expression for the free energy of W({phi}) ={phi}{sup 2k} in nlgYM{sub 2} theories at the strong coupling phase (SCP) regime (A > A{sub c}) for large groups. In the specific {phi}{sup 4} model, we show that the theory has a third order phase transition. (orig.)

  11. SU-E-I-20: Comprehensive Quality Assurance Test of Second Generation Toshiba Aquilion Large Bore CT Simulator Based On AAPM TG-66 Recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, D [Toshiba America Medical Systems, Tustin, CA (United States)

    2015-06-15

    Purpose: AAPM radiation therapy committee task group No. 66 (TG-66) published a report which described a general approach to CT simulator QA. The report outlines the testing procedures and specifications for the evaluation of patient dose, radiation safety, electromechanical components, and image quality for a CT simulator. The purpose of this study is to thoroughly evaluate the performance of a second generation Toshiba Aquilion Large Bore CT simulator with 90 cm bore size (Toshiba, Nasu, JP) based on the TG-66 criteria. The testing procedures and results from this study provide baselines for a routine QA program. Methods: Different measurements and analysis were performed including CTDIvol measurements, alignment and orientation of gantry lasers, orientation of the tabletop with respect to the imaging plane, table movement and indexing accuracy, Scanogram location accuracy, high contrast spatial resolution, low contrast resolution, field uniformity, CT number accuracy, mA linearity and mA reproducibility using a number of different phantoms and measuring devices, such as CTDI phantom, ACR image quality phantom, TG-66 laser QA phantom, pencil ion chamber (Fluke Victoreen) and electrometer (RTI Solidose 400). Results: The CTDI measurements were within 20% of the console displayed values. The alignment and orientation for both gantry laser and tabletop, as well as the table movement and indexing and scanogram location accuracy were within 2mm as specified in TG66. The spatial resolution, low contrast resolution, field uniformity and CT number accuracy were all within ACR’s recommended limits. The mA linearity and reproducibility were both well below the TG66 threshold. Conclusion: The 90 cm bore size second generation Toshiba Aquilion Large Bore CT simulator that comes with 70 cm true FOV can consistently meet various clinical needs. The results demonstrated that this simulator complies with the TG-66 protocol in all aspects including electromechanical component

  12. Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress

    Directory of Open Access Journals (Sweden)

    Tadashi Ishida

    2016-09-01

    Full Text Available A microfluidic device capable of precise chemical control is helpful to mimic tumor microenvironments in vitro, which are closely associated with malignant progression, including metastasis. Cancer cells under a concentration gradient of oxygen and other sustenance materials inside a tumor in vivo have recently been reported to increase the probability of metastasis. The influence of glucose concentration on cancer cells has not been measured well, whereas that of oxygen concentration has been thoroughly examined using microfluidic devices. This is because glucose concentrations can be controlled using microfluidic concentration gradient generators, which trade off temporal stability of the glucose concentration and shear stress on the cells; by contrast, oxygen concentration can be easily controlled without microfluidic device-induced shear stresses. To study cell division and migration responses as a function of glucose concentration, we developed a microfluidic device to observe cell behaviors under various chemical conditions. The device has small-cross-section microchannels for generating a concentration gradient and a large-cross-section chamber for cell culture. With this design, the device can achieve both a cell culture with sufficiently low shear stress on cell activity and a stable glucose concentration gradient. Experiments revealed that a low glucose concentration increased the total migration length of HeLa cells and that HeLa cells under a glucose concentration gradient exhibit random motion rather than chemotaxis.

  13. NGS-QCbox and Raspberry for Parallel, Automated and Rapid Quality Control Analysis of Large-Scale Next Generation Sequencing (Illumina) Data

    Science.gov (United States)

    Katta, Mohan A. V. S. K.; Khan, Aamir W.; Doddamani, Dadakhalandar; Thudi, Mahendar; Varshney, Rajeev K.

    2015-01-01

    Rapid popularity and adaptation of next generation sequencing (NGS) approaches have generated huge volumes of data. High throughput platforms like Illumina HiSeq produce terabytes of raw data that requires quick processing. Quality control of the data is an important component prior to the downstream analyses. To address these issues, we have developed a quality control pipeline, NGS-QCbox that scales up to process hundreds or thousands of samples. Raspberry is an in-house tool, developed in C language utilizing HTSlib (v1.2.1) (http://htslib.org), for computing read/base level statistics. It can be used as stand-alone application and can process both compressed and uncompressed FASTQ format files. NGS-QCbox integrates Raspberry with other open-source tools for alignment (Bowtie2), SNP calling (SAMtools) and other utilities (bedtools) towards analyzing raw NGS data at higher efficiency and in high-throughput manner. The pipeline implements batch processing of jobs using Bpipe (https://github.com/ssadedin/bpipe) in parallel and internally, a fine grained task parallelization utilizing OpenMP. It reports read and base statistics along with genome coverage and variants in a user friendly format. The pipeline developed presents a simple menu driven interface and can be used in either quick or complete mode. In addition, the pipeline in quick mode outperforms in speed against other similar existing QC pipeline/tools. The NGS-QCbox pipeline, Raspberry tool and associated scripts are made available at the URL https://github.com/CEG-ICRISAT/NGS-QCbox and https://github.com/CEG-ICRISAT/Raspberry for rapid quality control analysis of large-scale next generation sequencing (Illumina) data. PMID:26460497

  14. NGS-QCbox and Raspberry for Parallel, Automated and Rapid Quality Control Analysis of Large-Scale Next Generation Sequencing (Illumina) Data.

    Science.gov (United States)

    Katta, Mohan A V S K; Khan, Aamir W; Doddamani, Dadakhalandar; Thudi, Mahendar; Varshney, Rajeev K

    2015-01-01

    Rapid popularity and adaptation of next generation sequencing (NGS) approaches have generated huge volumes of data. High throughput platforms like Illumina HiSeq produce terabytes of raw data that requires quick processing. Quality control of the data is an important component prior to the downstream analyses. To address these issues, we have developed a quality control pipeline, NGS-QCbox that scales up to process hundreds or thousands of samples. Raspberry is an in-house tool, developed in C language utilizing HTSlib (v1.2.1) (http://htslib.org), for computing read/base level statistics. It can be used as stand-alone application and can process both compressed and uncompressed FASTQ format files. NGS-QCbox integrates Raspberry with other open-source tools for alignment (Bowtie2), SNP calling (SAMtools) and other utilities (bedtools) towards analyzing raw NGS data at higher efficiency and in high-throughput manner. The pipeline implements batch processing of jobs using Bpipe (https://github.com/ssadedin/bpipe) in parallel and internally, a fine grained task parallelization utilizing OpenMP. It reports read and base statistics along with genome coverage and variants in a user friendly format. The pipeline developed presents a simple menu driven interface and can be used in either quick or complete mode. In addition, the pipeline in quick mode outperforms in speed against other similar existing QC pipeline/tools. The NGS-QCbox pipeline, Raspberry tool and associated scripts are made available at the URL https://github.com/CEG-ICRISAT/NGS-QCbox and https://github.com/CEG-ICRISAT/Raspberry for rapid quality control analysis of large-scale next generation sequencing (Illumina) data.

  15. Study On Rotor with Large Type Wind Power Generator%风力发电机转子有限元仿真分析

    Institute of Scientific and Technical Information of China (English)

    刘志勇; 傅彩明; 毛文贵

    2012-01-01

    基于虚拟样机仿真,建立大型风力发电机转子三维模型,应用Nastran仿真系统对转子圆锥支撑方式和筋支撑方式结构进行强度和刚度分析,并对转子支架结构以铸铁件代替焊接件进行可行性分析,仿真分析结果表明:圆锥支撑形方式比筋支撑方式的应力和位移小;转子支架用铸铁件形式比焊接件形式的应力、位移都小些.仿真结果对转子结构优化具有指导意义.%Based on virtual prototyping simulation,three dimension model(solid model) of the rotor with a large type wind power generator is built,and virtual prototyping model of the rotor is established by a 3-D modeling software and Pro/Engineer. The solid model and virtual prototype model of circular cone brace type and muscle brace type structure are built. The analysis results of stress and displacement by using MSC. NASTRAN are presented. And the feasibility analysis of cast iron and weldment stock generation of rotor support structure is made. Based on results of simulation, this study provides guidana for optimizating the rotor of wind power generator.

  16. NGS-QCbox and Raspberry for Parallel, Automated and Rapid Quality Control Analysis of Large-Scale Next Generation Sequencing (Illumina Data.

    Directory of Open Access Journals (Sweden)

    Mohan A V S K Katta

    Full Text Available Rapid popularity and adaptation of next generation sequencing (NGS approaches have generated huge volumes of data. High throughput platforms like Illumina HiSeq produce terabytes of raw data that requires quick processing. Quality control of the data is an important component prior to the downstream analyses. To address these issues, we have developed a quality control pipeline, NGS-QCbox that scales up to process hundreds or thousands of samples. Raspberry is an in-house tool, developed in C language utilizing HTSlib (v1.2.1 (http://htslib.org, for computing read/base level statistics. It can be used as stand-alone application and can process both compressed and uncompressed FASTQ format files. NGS-QCbox integrates Raspberry with other open-source tools for alignment (Bowtie2, SNP calling (SAMtools and other utilities (bedtools towards analyzing raw NGS data at higher efficiency and in high-throughput manner. The pipeline implements batch processing of jobs using Bpipe (https://github.com/ssadedin/bpipe in parallel and internally, a fine grained task parallelization utilizing OpenMP. It reports read and base statistics along with genome coverage and variants in a user friendly format. The pipeline developed presents a simple menu driven interface and can be used in either quick or complete mode. In addition, the pipeline in quick mode outperforms in speed against other similar existing QC pipeline/tools. The NGS-QCbox pipeline, Raspberry tool and associated scripts are made available at the URL https://github.com/CEG-ICRISAT/NGS-QCbox and https://github.com/CEG-ICRISAT/Raspberry for rapid quality control analysis of large-scale next generation sequencing (Illumina data.

  17. Reliable and inexpensive expression of large, tagged, exogenous proteins in murine bone marrow-derived macrophages using a second generation lentiviral system

    Directory of Open Access Journals (Sweden)

    Matthew R. Miller

    2015-08-01

    Full Text Available Over the past two decades, researchers have struggled to efficiently express foreign DNA in primary macrophages, impeding research progress. The applications of lipofection, electroporation, microinjection, and viral-mediated transfer typically result in disruptions in macrophage differentiation and function, low expression levels of exogenous proteins, limited efficiency and high cell mortality. In this report, after extensive optimization, we present a method of expressing large tagged proteins at high efficiency, consistency, and low cost using lentiviral infection. This method utilizes laboratory-propagated second generation plasmids to produce efficient virus that can be stored for later use. The expression of proteins up to 150 kDa in size is achieved in 30–70% of cells while maintaining normal macrophage differentiation and morphology as determined by fluorescence microscopy and Western blot analysis. This manuscript delineates the reagents and methods used to produce lentivirus to express exogenous DNA in murine bone marrow-derived macrophages sufficient for single cell microscopy as well as functional assays requiring large numbers of murine bone marrow-derived macrophages.

  18. 含风电场的双层电源规划%Bi-level Generation Expansion Planning With Large-Scale Wind Farms

    Institute of Scientific and Technical Information of China (English)

    张节潭; 苗淼; 范宏; 程浩忠; 张洪平; 姚良忠; Bazargan Masoud

    2011-01-01

    The impacts of wind farms on system peak regulation, frequency regulation, and environmental protection are analyzed. To take above-mentioned impacts of wind farms into account and the impact of different generation price on investment decision, based on the idea of decomposition coordination, a bi-level generation expansion planning model for power grid containing large-scale wind farms is built. In this model the net earning maximization and the constraints of peak regulation, frequency regulation and environment protection are considered, in addition the influence of the differences among pool purchase prices on generation expansion planning is taken into account. The upper-level planning is a power source investment decision-making problem, so the total revenue maximization of gencos is taken as objective function and the decision variables are the construction time of the power plants to be build and the numbers of the generators to be installed in these plants, the retirement time of existing power plants and numbers of generators in these plants; the lower-level planning is a production optimization decision problem that can be divided into two subproblems, namely the maintenance scheduling and stochastic production simulation, and the decision variables are maintenance time intervals of generating units and the operating positions of generating units on load curve. To solve the proposed model, the plant growth simulation algorithm is integrated with minimum cumulative risk algorithm and equivalent energy and frequency function method is adopted. The feasibility and efficiency of the proposed model are verified by the results of numerical example.%按分解协调的思想,建立了考虑调峰、调频及环保约束的净收益最大化双层电源规划模型,计及了上网电价差异对电源规划的影响。上层规划为电源投资决策问题,以发电商总收益最大为目标函数,决策变量是待选电厂的投建时间和台数以

  19. Gravity Fields Generation In The Universe By The Large Range of Scales Convection Systems In Planets, Stars, Black Holes and Galaxies Based On The "Convection Bang Hypothesis"

    Science.gov (United States)

    Gholibeigian, H.; Amirshahkarami, A.; Gholibeigian, K.

    2015-12-01

    In our vision it is believed that the Big Bang was Convection Bang (CB). When CB occurred, a gigantic large-scale forced convection system (LFCS) began to create space-time including gravitons and gluons in more than light speed. Then, simultaneously by a swirling wild wind, created inflation process including many quantum convection loops (QCL) in locations which had more density of temperature and energetic particles like gravitons. QCL including fundamental particles, grew and formed black holes (BHs) as the core of galaxies. LFCSs of heat and mass in planets, stars, BHs and galaxies generate gravity and electromagnetic fields and change the properties of matter and space-time around the systems. Mechanism: Samples: 1- Due to gravity fields of Sun and Moon, Earth's inner core is dislocated toward them and rotates around the Earth's center per day and generates LFCSs, Gholibeigian [AGU, 2012]. 2- Dislocated Sun's core due to gravity fields of planets/ Jupiter, rotates around the Sun's center per 25-35 days and generates LFCSs, Gholibeigian [EGU, 2014]. 3- If a planet/star falls into a BH, what happens? It means, its dislocated core rotates around its center in less than light speed and generates very fast LFCS and friction, while it is rotating/melting around/inward the center of BH. Observable Factors: 1- There is not logical relation between surface gravity fields of planets/Sun and their masses (general relativity); see Planetary Fact Sheet/Ratio to Earth Values-NASA: Earth: mass/gravity =1/1, Jupiter=317.8/2.36, Neptune=17.1/1.12, Saturn=95.2/0.916, Moon=0.0128/0.166, Sun=333000/28. 2- Convective systems in thunderstorms help bring ozone down to Earth [Brian-Kahn]. 3- In 12 surveyed BHs, produced gravity force & magnetic field strength were matched (unique LFCS source) [PhysOrg - June 4, 2014]. Justification: After BB/CB, gravitons were created without any other masses and curvature of space-time (general relativity), but by primary gigantic convection

  20. Next-Generation Sequencing and Comparative Analysis of Sequential Outbreaks Caused by Multidrug-Resistant Acinetobacter baumannii at a Large Academic Burn Center.

    Science.gov (United States)

    Kanamori, Hajime; Parobek, Christian M; Weber, David J; van Duin, David; Rutala, William A; Cairns, Bruce A; Juliano, Jonathan J

    2015-12-07

    Next-generation sequencing (NGS) analysis has emerged as a promising molecular epidemiological method for investigating health care-associated outbreaks. Here, we used NGS to investigate a 3-year outbreak of multidrug-resistant Acinetobacter baumannii (MDRAB) at a large academic burn center. A reference genome from the index case was generated using de novo assembly of PacBio reads. Forty-six MDRAB isolates were analyzed by pulsed-field gel electrophoresis (PFGE) and sequenced using an Illumina platform. After mapping to the index case reference genome, four samples were excluded due to low coverage, leaving 42 samples for further analysis. Multilocus sequence types (MLST) and the presence of acquired resistance genes were also determined from the sequencing data. A transmission network was inferred from genomic and epidemiological data using a Bayesian framework. Based on single-nucleotide variant (SNV) differences, this MDRAB outbreak represented three sequential outbreaks caused by distinct clones. The first and second outbreaks were caused by sequence type 2 (ST2), while the third outbreak was caused by ST79. For the second outbreak, the MLST and PFGE results were discordant. However, NGS-based SNV typing detected a recombination event and consequently enabled a more accurate phylogenetic analysis. The distribution of resistance genes varied among the three outbreaks. The first- and second-outbreak strains possessed a blaOXA-23-like group, while the third-outbreak strains harbored a blaOXA-40-like group. NGS-based analysis demonstrated the superior resolution of outbreak transmission networks for MDRAB and provided insight into the mechanisms of strain diversification between sequential outbreaks through recombination.

  1. Next-Generation Sequencing and Comparative Analysis of Sequential Outbreaks Caused by Multidrug-Resistant Acinetobacter baumannii at a Large Academic Burn Center

    Science.gov (United States)

    Parobek, Christian M.; Weber, David J.; van Duin, David; Rutala, William A.; Cairns, Bruce A.; Juliano, Jonathan J.

    2015-01-01

    Next-generation sequencing (NGS) analysis has emerged as a promising molecular epidemiological method for investigating health care-associated outbreaks. Here, we used NGS to investigate a 3-year outbreak of multidrug-resistant Acinetobacter baumannii (MDRAB) at a large academic burn center. A reference genome from the index case was generated using de novo assembly of PacBio reads. Forty-six MDRAB isolates were analyzed by pulsed-field gel electrophoresis (PFGE) and sequenced using an Illumina platform. After mapping to the index case reference genome, four samples were excluded due to low coverage, leaving 42 samples for further analysis. Multilocus sequence types (MLST) and the presence of acquired resistance genes were also determined from the sequencing data. A transmission network was inferred from genomic and epidemiological data using a Bayesian framework. Based on single-nucleotide variant (SNV) differences, this MDRAB outbreak represented three sequential outbreaks caused by distinct clones. The first and second outbreaks were caused by sequence type 2 (ST2), while the third outbreak was caused by ST79. For the second outbreak, the MLST and PFGE results were discordant. However, NGS-based SNV typing detected a recombination event and consequently enabled a more accurate phylogenetic analysis. The distribution of resistance genes varied among the three outbreaks. The first- and second-outbreak strains possessed a blaOXA-23-like group, while the third-outbreak strains harbored a blaOXA-40-like group. NGS-based analysis demonstrated the superior resolution of outbreak transmission networks for MDRAB and provided insight into the mechanisms of strain diversification between sequential outbreaks through recombination. PMID:26643351

  2. OpTIIX: An ISS-Based Testbed Paving the Roadmap Toward a Next Generation Large Aperture UV/Optical Space Telescope

    Science.gov (United States)

    Carpenter, Kenneth G.; Etemad, Shar; Seery, Bernard D.; Thronson, Harley; Burdick, Gary M.; Coulter, Dan; Goullioud, Renaud; Green, Joseph J.; Liu, Fengchuan; Ess, Kim; hide

    2012-01-01

    The next generation large aperture UV/Optical space telescope will need a diameter substantially larger than even that of JWST in order to address some of the most compelling unanswered scientific quests. These quests include understanding the earliest phases of the Universe and detecting life on exo-planets by studying spectra of their atmospheres. Such 8-16 meter telescopes face severe challenges in terms of cost and complexity and are unlikely to be affordable unless a new paradigm is adopted for their design and construction. The conventional approach is to use monolithic or preassembled segmented mirrors requiring complicated and risky deployments and relying on future heavy-lift vehicles, large fairings and complex geometry. The new paradigm is to launch component modules on relatively small vehicles and then perform in-orbit robotic assembly of those modules. The Optical Testbed and Integration on ISS eXperiment (OpTIIX) is designed to demonstrate, at low cost by leveraging the infrastructure provided by ISS, telescope assembly technologies and end-to-end optical system technologies. The use of ISS as a testbed permits the concentration of resources on reducing the technical risks associated with robotically integrating the components. These include laser metrology and wavefront sensing and control (WFS&C) systems, an imaging instrument, lightweight, low-cost deformable primary mirror segments and the secondary mirror. These elements are then aligned to a diffraction-limited optical system in space. The capability to assemble the optical system and remove and replace components via the existing ISS robotic systems like the Special Purpose Dexterous Manipulator (SPDM), or by the ISS flight crew, allows for future experimentation, as well as repair.

  3. Diagnosis for choroideremia in a large Chinese pedigree by next-generation sequencing (NGS) and non-invasive prenatal testing (NIPT)

    Science.gov (United States)

    Zhu, Li; Cheng, Jingliang; Zhou, Boxu; Wei, Chunli; Yang, Weichan; Jiang, Dong; Ijaz, Iqra; Tan, Xiaojun; Chen, Rui; Fu, Junjiang

    2017-01-01

    To develop an effective strategy to isolate and use cell-free fetal DNA (cffDNA) for the combined use of next-generation sequencing (NGS) for diagnosing choroideremia and non-invasive prenatal testing (NIPT) for Y chromosome determination, a large Chinese family with an X-linked recessive disease, choroideremia, was recruited. Cell-free DNA was extracted from maternal plasma, and SRY polymerase chain reaction amplification was performed using NIPT. Sanger sequencing was subsequently used for fetal amniotic fluid DNA verification. A nonsense mutation (c.C799T:p.R267X) of the CHM gene on the X chromosome of the proband (IV:7) and another 5 males with choroideremia were detected, while 3 female carriers with no symptoms were also identified. The fetus (VI:7) was identified as female from the cffDNA, and the same heterozygous nonsense mutation present in her mother was also confirmed. At one and a half years of age, the female baby did not present with any associated symptoms of choroideremia. Therefore, cffDNA was successfully used for the combined use of NGS for diagnosing choroideremia in a large Chinese pedigree, and NIPT for Y chromosome determination. This approach should result in a markedly increased use of prenatal diagnosis and improvement, and more sophisticated clinical management of diseases in China and other developing countries. The establishment of a highly accurate method for prenatal gene diagnosis will allow for more reliable gene diagnosis, improved genetic counseling, and personalized clinical management of our patients. PMID:28098911

  4. The Equatorial Annual Oscillation (EAO) as Upper Atmosphere Pacemaker for Generating the Large Solar Cycle Modulation of the QBO in the Stratosphere: Model Simulations and Observations

    Science.gov (United States)

    Mayr, H. G.; Lee, J. N.

    2014-12-01

    Very large solar cycle (SC) variations are observed in the zonal winds and temperatures of the quasi-biennial oscillation (QBO). The effect is too large to be produced by the small SC variations of the solar flux in the lower stratosphere. Dynamical downward coupling must be involved, and we present a review of the mechanism that emerged from studies with the Numerical Spectral Model (NSM). In the NSM, the QBO is generated with parameterized gravity waves and planetary waves. For a SC period of 10 years, the applied heat source varies exponentially with altitude: 0.2% (surface), 2% (50 km), 20% (100 km and above). With that solar forcing, the model reproduces qualitatively the SC modulations of the QBO zonal winds around the equator and temperature variations extending to high latitudes. The QBO is spawned in the lower mesosphere by a hemispherically symmetric equatorial annual oscillation (EAO) of the zonal wind velocities. Though small in magnitude, the SC modulation of the EAO is large. Like the symmetric QBO, the EAO extends into the lower atmosphere under the influence of, and amplified by, wave mean flow interactions. The amplitude modulations of the QBO and EAO are in phase with the imposed SC heat source. Essentially, the EAO provides the pathway and pacemaker for the SC modulation of the QBO - and wave interactions amplify the oscillations as they propagate down into the lower atmosphere. Analysis of NCEP temperature and zonal wind data (1958 to 2006) produces the hemispherically symmetric equatorial annual oscillation (EAO), and it contains spectral signatures with periods around 11 years. Moving windows of 44 years show that below 20 km the 11-year modulation of the EAO is phase locked to the SC. The spectral features from the 48-year data record reveal modulation signatures of 9.6 and 12 years, which produce EAO variations that mimic in limited altitude regimes the varying maxima and minima of the 10.7 cm solar index. In the lower stratosphere, the 40

  5. The Large Hadron Collider and the Super Proton Synchrotron at CERN as Tools to Generate Warm Dense Matter and Non–Ideal Plasmas

    CERN Document Server

    Tahir, N A; Shutov, A; Lomonosov, I V; Gryaznov, V; Piriz, A R; Deutsch, C; Fortov, V E

    2011-01-01

    The largest accelerator in the world, the Large Hadron Collider (LHC) at CERN, has entered into commission- ing phase. It is expected that when this impressive machine will become fully operational, it will generate two counter rotating 7 TeV/c proton beams that will be made to collide, leading to an unprecedented luminosity of 1034 cm−2s−1. Total energy stored in each LHC beam is about 362 MJ, sufficient to melt 500 kg copper. Safety of operation is a very critical issue when working with such extremely powerful beams. It is important to know the consequences of an accidental release of the beam energy in order to design protection system for the equipment. For this purpose we have carried out extensive numerical simulations of the interaction of one full LHC beam with copper and graphite targets which are materials of practical importance. Our calculations have shown that the LHC protons will penetrate up to about 35 m in solid copper and 10 m in solid graphite. A very interesting outcome of this work i...

  6. The Large Hadron Collider and the Super Proton Synchrotron at CERN as Tools to Generate Warm Dense Matter and Non-Ideal Plasmas

    CERN Document Server

    Tahir, N A; Deutsch, C; Gryaznov, V; Lomonosov, I V; Shutov, A; Piriz, A R; Fortov, V E; Geissel, H; Redmer, R

    2011-01-01

    The largest accelerator in the world, the Large Hadron Collider (LHC) at CERN, has entered into commissioning phase. It is expected that when this impressive machine will become fully operational, it will generate two counter rotating 7 TeV/c proton beams that will be made to collide, leading to an unprecedented luminosity of 10(34) cm(-2)s(-1). Total energy stored in each LHC beam is about 362 MJ, sufficient to melt 500 kg copper. Safety of operation is a very critical issue when working with such extremely powerful beams. It is important to know the consequences of an accidental release of the beam energy in order to design protection system for the equipment. For this purpose we have carried out extensive numerical simulations of the interaction of one full LHC beam with copper and graphite targets which are materials of practical importance. Our calculations have shown that the LHC protons will penetrate up to about 35 m in solid copper and 10 m in solid graphite. A very interesting outcome of this work i...

  7. Effects of Heat Loss and Subgrid-Scale Models on Large Eddy Simulations of a Premixed Jet Combustor Using Flamelet-Generated Manifolds

    Science.gov (United States)

    Hernandez Perez, Francisco E.; Lee, Bok Jik; Im, Hong G.; Fancello, Alessio; Donini, Andrea; van Oijen, Jeroen A.; de Goey, L. Philip H.

    2016-11-01

    Large eddy simulations (LES) of a turbulent premixed jet flame in a confined chamber are performed using the flamelet-generated manifold technique for tabulation of chemical kinetics and the OpenFOAM framework for computational fluid dynamics. The configuration is characterized by an off-center nozzle having an inner diameter of 10 mm, feeding a lean methane-air mixture with an equivalence ratio of 0.71 and mean velocity of 90 m/s, at 573 K and atmospheric pressure. Conductive heat loss is accounted for in the manifold via burner-stabilized flamelets and the subgrid-scale (SGS) turbulence-chemistry interaction is modeled via presumed filtered density functions. The effects of heat loss inclusion as well as SGS modeling for both the SGS stresses and SGS variance of progress variable on the numerical predictions are all systematically investigated. Comparisons between numerical results and measured data show a considerable improvement in the prediction of temperature when heat losses are incorporated into the manifold, as compared to the adiabatic one. In addition, further improvements in the LES predictions are achieved by employing SGS models based on transport equations.

  8. Large Eddy Simulations of a Premixed Jet Combustor Using Flamelet-Generated Manifolds: Effects of Heat Loss and Subgrid-Scale Models

    KAUST Repository

    Hernandez Perez, Francisco E.

    2017-01-05

    Large eddy simulations of a turbulent premixed jet flame in a confined chamber were conducted using the flamelet-generated manifold technique for chemistry tabulation. The configuration is characterized by an off-center nozzle having an inner diameter of 10 mm, supplying a lean methane-air mixture with an equivalence ratio of 0.71 and a mean velocity of 90 m/s, at 573 K and atmospheric pressure. Conductive heat loss is accounted for in the manifold via burner-stabilized flamelets and the subgrid-scale (SGS) turbulencechemistry interaction is modeled via presumed probability density functions. Comparisons between numerical results and measured data show that a considerable improvement in the prediction of temperature is achieved when heat losses are included in the manifold, as compared to the adiabatic one. Additional improvement in the temperature predictions is obtained by incorporating radiative heat losses. Moreover, further enhancements in the LES predictions are achieved by employing SGS models based on transport equations, such as the SGS turbulence kinetic energy equation with dynamic coefficients. While the numerical results display good agreement up to a distance of 4 nozzle diameters downstream of the nozzle exit, the results become less satisfactory along the downstream, suggesting that further improvements in the modeling are required, among which a more accurate model for the SGS variance of progress variable can be relevant.

  9. Unexpected generation of super-high energetic electrons at relativistic circularly polarized laser-solid interactions in the presence of large scale pre-plasmas

    CERN Document Server

    Wu, D; Luan, S X; Yu, W

    2015-01-01

    As a continuation of the previous work "Identifying the source of super-high energetic electrons in the presence of pre-plasma in laser-matter interaction at relativistic intensities [arXiv: 1512.02411]", we have investigated the role of circularly polarized (CP) laser pulses while keeping other conditions the same. It is found that in the presence of large scale pre-formed plasmas, super-high energetic electrons can be generated at relativistic CP laser-solid interactions. For laser of intensity 10$^{20}\\ $W$/$cm$^2$ and pre-plasma scale-length 10$\\ \\mu$m, the cut-off energy of electron by CP laser is 120$\\ $MeV compared with 100$\\ $MeV in the case of linearly polarized (LP) laser. The unexpected super-high energetic electron acceleration can also be explained by the two-stage acceleration model, by considering the polarization transition of the reflected laser from CP to elliptically polarized (EP). The polarization state transition is addressed, and a modified scaling law in the presence of EP laser is obt...

  10. Electrical efficiency and renewable energy - Economical alternatives to large-scale power generation; Stromeffizienz und erneuerbare Energien - Wirtschaftliche alternative zu Grosskraftwerken

    Energy Technology Data Exchange (ETDEWEB)

    Oettli, B.; Hammer, S.; Moret, F.; Iten, R. [Infras, Zuerich (Switzerland); Nordmann, T. [TNC Consulting AG, Erlenbach (Switzerland)

    2010-05-15

    This final report for WWF Switzerland, Greenpeace Switzerland, the Swiss Energy Foundation SES, Pro Natura and the Swiss Cantons of Basel City and Geneva takes a look at the energy-relevant effects of the propositions made by Swiss electricity utilities for large-scale power generation. These proposals are compared with a strategy that proposes investments in energy-efficiency and the use of renewable sources of energy. The effects of both scenarios on the environment and the risks involved are discussed, as are the investments involved. The associated effects on the Swiss national economy are also discussed. For the efficiency and renewables scenario, two implementation variants are discussed: Inland investments and production are examined as are foreign production options and/or import from foreign countries. The methods used in the study are introduced and discussed. Investment and cost considerations, earnings and effects on employment are also reviewed. The report is completed with an extensive appendix which, amongst other things, includes potential reviews, cost estimates and a discussion on 'smart grids'

  11. Towards a general method for estimating the unbalanced magnetic pull in mixed eccentricities motion including sufficiently large eccentricities in a hydropower generator and their validation against EM simulations

    Science.gov (United States)

    Calleecharan, Yogeshwarsing; Jauregui, Ricardo; Aidanpää, Jan-Olov

    2013-08-01

    Electromagnetic (EM) analysis of hydropower generators is common practice but rotor whirling is little studied. This paper suggests a novel semi-analytical method for estimating the steady state unbalanced magnetic pull (UMP) when the rotor centre is undergoing mixed eccentricities motion. The ability to estimate the UMP for mixed eccentricities motion in finite element method (FEM)-based modelling software packages is rare. The proposed methodology in its formulation takes advantage of the fact that a purely dynamic eccentricity motion including non-synchronous whirling and a purely static eccentricity motion can be more amenable to implement in existing FEM-based EM modelling software products for UMP estimation. After these initial separate UMP results are obtained, the proposed method can be applied for virtually any mixed eccentricities motion cases up to sufficiently large eccentricities for quick analysis instead of running the mixed eccentricities simulations directly in a FEM-based software package. Good agreement between the UMP from the actual EM mixed eccentricities motion simulations in a commercial FEM-based software package and the UMP estimations by the novel method is made for a wide range of eccentricities that may commonly occur in practice. A modified feature selective validation (FSV) method, the FSV-UPC, is applied to assess the similarities and the differences in the UMP computations.

  12. Leveraging the power of multi-core platforms for large-scale geospatial data processing: Exemplified by generating DEM from massive LiDAR point clouds

    Science.gov (United States)

    Guan, Xuefeng; Wu, Huayi

    2010-10-01

    In recent years improvements in spatial data acquisition technologies, such as LiDAR, resulted in an explosive increase in the volume of spatial data, presenting unprecedented challenges for computation capacity. At the same time, the kernel of computing platforms the CPU, also evolved from a single-core to multi-core architecture. This radical change significantly affected existing data processing algorithms. Exemplified by the problem of generating DEM from massive air-borne LiDAR point clouds, this paper studies how to leverage the power of multi-core platforms for large-scale geospatial data processing and demonstrates how multi-core technologies can improve performance. Pipelining is adopted to exploit the thread level parallelism of multi-core platforms. First, raw point clouds are partitioned into overlapped blocks. Second, these discrete blocks are interpolated concurrently on parallel pipelines. On the interpolation run, intermediate results are sorted and finally merged into an integrated DEM. This parallelization demonstrates the great potential of multi-core platforms with high data throughput and low memory footprint. This approach achieves excellent performance speedup with greatly reduced processing time. For example, on a 2.0 GHz Quad-Core Intel Xeon platform, the proposed parallel approach can process approximately one billion LiDAR points (16.4 GB) in about 12 min and produces a 27,500×30,500 raster DEM, using less than 800 MB main memory.

  13. ANEMOS: Development of a next generation wind power forecasting system for the large-scale integration of onshore and offshore wind farms.

    Science.gov (United States)

    Kariniotakis, G.; Anemos Team

    2003-04-01

    Objectives: Accurate forecasting of the wind energy production up to two days ahead is recognized as a major contribution for reliable large-scale wind power integration. Especially, in a liberalized electricity market, prediction tools enhance the position of wind energy compared to other forms of dispatchable generation. ANEMOS, is a new 3.5 years R&D project supported by the European Commission, that resembles research organizations and end-users with an important experience on the domain. The project aims to develop advanced forecasting models that will substantially outperform current methods. Emphasis is given to situations like complex terrain, extreme weather conditions, as well as to offshore prediction for which no specific tools currently exist. The prediction models will be implemented in a software platform and installed for online operation at onshore and offshore wind farms by the end-users participating in the project. Approach: The paper presents the methodology of the project. Initially, the prediction requirements are identified according to the profiles of the end-users. The project develops prediction models based on both a physical and an alternative statistical approach. Research on physical models gives emphasis to techniques for use in complex terrain and the development of prediction tools based on CFD techniques, advanced model output statistics or high-resolution meteorological information. Statistical models (i.e. based on artificial intelligence) are developed for downscaling, power curve representation, upscaling for prediction at regional or national level, etc. A benchmarking process is set-up to evaluate the performance of the developed models and to compare them with existing ones using a number of case studies. The synergy between statistical and physical approaches is examined to identify promising areas for further improvement of forecasting accuracy. Appropriate physical and statistical prediction models are also developed for

  14. Second-generation sequencing supply an effective way to screen RNAi targets in large scale for potential application in pest insect control.

    Science.gov (United States)

    Wang, Yubing; Zhang, Hao; Li, Haichao; Miao, Xuexia

    2011-04-11

    The key of RNAi approach success for potential insect pest control is mainly dependent on careful target selection and a convenient delivery system. We adopted second-generation sequencing technology to screen RNAi targets. Illumina's RNA-seq and digital gene expression tag profile (DGE-tag) technologies were used to screen optimal RNAi targets from Ostrinia furnalalis. Total 14690 stage specific genes were obtained which can be considered as potential targets, and 47 were confirmed by qRT-PCR. Ten larval stage specific expression genes were selected for RNAi test. When 50 ng/µl dsRNAs of the genes DS10 and DS28 were directly sprayed on the newly hatched larvae which placed on the filter paper, the larval mortalities were around 40∼50%, while the dsRNAs of ten genes were sprayed on the larvae along with artificial diet, the mortalities reached 73% to 100% at 5 d after treatment. The qRT-PCR analysis verified the correlation between larval mortality and the down-regulation of the target gene expression. Topically applied fluorescent dsRNA confirmed that dsRNA did penetrate the body wall and circulate in the body cavity. It seems likely that the combination of DGE-tag with RNA-seq is a rapid, high-throughput, cost less and an easy way to select the candidate target genes for RNAi. More importantly, it demonstrated that dsRNAs are able to penetrate the integument and cause larval developmental stunt and/or death in a lepidopteron insect. This finding largely broadens the target selection for RNAi from just gut-specific genes to the targets in whole insects and may lead to new strategies for designing RNAi-based technology against insect damage.

  15. Generative Semantics

    Science.gov (United States)

    Bagha, Karim Nazari

    2011-01-01

    Generative semantics is (or perhaps was) a research program within linguistics, initiated by the work of George Lakoff, John R. Ross, Paul Postal and later McCawley. The approach developed out of transformational generative grammar in the mid 1960s, but stood largely in opposition to work by Noam Chomsky and his students. The nature and genesis of…

  16. Newest-generation drug-eluting and bare-metal stents combined with prasugrel-based antiplatelet therapy in large coronary arteries

    DEFF Research Database (Denmark)

    Jeger, Raban; Pfisterer, Matthias; Alber, Hannes

    2012-01-01

    In the BAsel Stent Kosten Effektivitäts Trial PROspective Validation Examination (BASKET-PROVE), drug-eluting stents (DESs) had similar 2-year rates of death and myocardial infarction but lower rates of target vessel revascularization and major adverse cardiac events compared with bare-metal sten...... (BMSs). However, comparative clinical effects of newest-generation DES with biodegradable polymers vs second-generation DES or newest-generation BMS with biocompatible coatings, all combined with a prasugrel-based antiplatelet therapy, on 2-year outcomes are not known....

  17. 大型水轮发电机冷却方式综合评价方法的研究∗%Comprehensive evaluation metho d in the co oling mo de of large-scale hydro-generators

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    With the development of large-scale hydro-generators, large hydro-generator cooling technology is increasingly demanded. Different cooling method will not only affect the structure of hydro-generators, also it will affect the energy consumption and reliability of the generators. The commonly large-scale hydro-generator cooling method includes: air cooling, water cooling, and evaporative cooling methods. This paper analyzes the principle of the three cooling methods and describes qualitatively the advantages and disadvantages of them. The air cooling hydro-generator structure is simple, but the generator operating temperature is high; the water-cooling method has a certain superior in cooling performance, but it requires more auxiliary equipments, and has higher equipment failure rates. The evaporative cooling method is a recently developed cooling technique. It not only has a remarkable cooling effect, but also can decrease the equipment failure rates and the cost of maintenance. In order to build a comprehensive model to assess the three hydro-generator cooling methods, this paper proposes a comprehensive evaluation method based on AHP. The method includes 11 indexes of resource consumption, energy consumption and reliability to assess the influence of cooling ways. The energy saving influence of all the 11 indicators are calculated by using the AHP comprehensive evaluation. Finally, comparison between a 400 MW air cooling and an evaporative cooling hydro-generators at Lijiaxia hydropower Station are made using the proposed method. Evaluation results indicate that in terms of daily operation, the energy saving of the evaporative cooling hydro-generator can be more than 300 tons standard coal equivalent per year as compared with that of air cooling generator. In terms of maintenance, the evaporative cooling method can save more than 5000 tons of standard coal equivalent per year. The comprehensive evaluation results show that the evaporative cooling method is

  18. Wind Generators

    Science.gov (United States)

    1989-01-01

    When Enerpro, Inc. president, Frank J. Bourbeau, attempted to file a patent on a system for synchronizing a wind generator to the electric utility grid, he discovered Marshall Space Flight Center's Frank Nola's power factor controller. Bourbeau advanced the technology and received a NASA license and a patent for his Auto Synchronous Controller (ASC). The ASC reduces generator "inrush current," which occurs when large generators are abruptly brought on line. It controls voltage so the generator is smoothly connected to the utility grid when it reaches its synchronous speed, protecting the components from inrush current damage. Generator efficiency is also increased in light winds by applying lower than rated voltage. Wind energy is utilized to drive turbines to generate electricity for utility companies.

  19. Application of photovoltaic generating system to electric power in large ship; Taiyoko hatsuden system no ogata senpaku eno oyo ni kansuru kento

    Energy Technology Data Exchange (ETDEWEB)

    Katagi, T.; Ogawa, S.; Nishikawa, E.; Hashimoto, T. [Kobe University of Mercantile Marine, Kobe (Japan); Ishida, K.

    1996-10-27

    This paper describes the design of electric power system in a ship with photovoltaic power generating system, to examine applicability of the photovoltaic power generating system to the inboard power source. It also discusses effectiveness of the system for sea environment. At first, the actual route of a car carrier, meteorological data, and quantity of power consumption were picked up from the deck logbook and engine logbook. Then, the installation area of photovoltaic arrays, the quantity of photovoltaic power generation derived from the quantity of solar radiation, and the capacities of batteries and inverters were calculated, to design the electric power system in the ship with photovoltaic power generation system. Moreover, the NOx and SOx emissions were compared between the present power system and the usual power system using diesel power generator, to discuss the effectiveness of the present system for sea environment. Consequently, it was found that the emission of NOx was reduced by about 33% and the emission of SOx was reduced by about 28% compared to the usual power system. The effectiveness for sea environment was confirmed. 9 refs., 5 figs., 4 tabs.

  20. Tele-operation of the electric power generation and transmission in large complex; Teleoperacao da geracao e transmissao de energia eletrica em complexo de grande porte

    Energy Technology Data Exchange (ETDEWEB)

    Martini, Jose Sidnei Colombo

    1992-07-01

    This work presents the specification and development outstanding aspects of a large supervisory and control power system. The engineering experiment, named SSCH - Hierarchical Supervision and Control System, occurred between 1982 and 1992 at Sao Paulo State and is an industrial automation power system most expressive cases carried out in this decade. More than complex development technical details, important management aspects concerning with large project execution are discussed. The SSCHs special characteristics are its dimension, complexity and realtime network analysis resources, applied to large power systems. (author)

  1. Data for generation of all Tables and Figures for CTEP publication in 2015 pertaining to large-scale diesel gensets tested

    Data.gov (United States)

    U.S. Environmental Protection Agency — particulate and gaseous emissions and particle optical properties for emissions from large-scale diesel gensets with and without aftermarket PM controls. This...

  2. Mid-infrared supercontinuum generation to 12.5μm in large NA chalcogenide step-index fibres pumped at 4.5μm

    DEFF Research Database (Denmark)

    Kubat, Irnis; Agger, Christian; Møller, Uffe Visbech

    2014-01-01

    was below 2.5dB/m in the 3.3-9.4μ m region. Fibres with 8 and 10μm core diameters generated an SC out to 12.5 and 10.7μm in less than 2m of fibre when pumped with 0.75 and 1kW, respectively. Larger core fibres with 20μm core diameters for potential higher power handling generated an SC out to 10.6μm...

  3. The impact of increased interconnection on electricity systems with large penetrations of wind generation: A case study of Ireland and Great Britain

    DEFF Research Database (Denmark)

    Denny, E.; Tuohy, A.; Meibom, Peter

    2010-01-01

    Increased interconnection has been highlighted as potentially facilitating the integration of wind generation in power systems by increasing the flexibility to balance the variable wind output. This paper utilizes a stochastic unit commitment model to simulate the impacts of increased interconnec...

  4. Benefits of coal-fired power generation with flexible CCS in a future northwest European power system with large scale wind power

    NARCIS (Netherlands)

    Van der Wijk, Pieter Cornelis; Brouwer, Anne Sjoerd; Van den Broek, Machteld; Slot, Thijs; Stienstra, Gerard; Van der Veen, Wim; Faaij, André P C

    2014-01-01

    Coal-fired power generation with carbon capture and storage (CCS) is projected as a cost-effective technology to decarbonize the power sector. Intermittent renewables could reduce its load factor and revenues, so flexible capture unit operation strategies (flexible CCS) have been suggested to increa

  5. Calculation of alternating current losses in stacks and coils made of second generation high temperature superconducting tapes for large scale applications

    DEFF Research Database (Denmark)

    Zermeno, Victor M. R.; Abrahamsen, Asger Bech; Mijatovic, Nenad;

    2013-01-01

    A homogenization method to model a stack of second generation High Temperature Superconducting tapes under AC applied transport current or magnetic field has been obtained. The idea is to find an anisotropic bulk equivalent for the stack such that the geometrical layout of the internal alternatin...

  6. Searches for supersymmetric partners of third generation quarks and measurement of the $t\\bar{t} + Z$ process using the ATLAS detector at the CERN Large Hadron Collider

    CERN Document Server

    McFayden, Joshua Angus

    This thesis presents results using data collected by the ATLAS experiment during 2011 and 2012 at $\\sqrt{s} = 7$ TeV and 8 TeV respectively. The focus of the work presented in this thesis is separated into two areas, measurement of the $t\\bar{t}+Z$ process and searches for the supersymmetric partners to third generation quarks. ...

  7. Benefits of coal-fired power generation with flexible CCS in a future northwest European power system with large scale wind power

    NARCIS (Netherlands)

    Van der Wijk, Pieter Cornelis; Brouwer, Anne Sjoerd|info:eu-repo/dai/nl/330822748; Van den Broek, Machteld|info:eu-repo/dai/nl/092946895; Slot, Thijs; Stienstra, Gerard; Van der Veen, Wim; Faaij, André P C

    Coal-fired power generation with carbon capture and storage (CCS) is projected as a cost-effective technology to decarbonize the power sector. Intermittent renewables could reduce its load factor and revenues, so flexible capture unit operation strategies (flexible CCS) have been suggested to

  8. Improvement of small-signal stability of power system by controlling doubly fed induction generators of a large-capacity wind farm

    Directory of Open Access Journals (Sweden)

    Tomohiro Adachi

    2016-01-01

    Full Text Available Many wind turbine generations have been installed into power systems around the world, where in recent years doubly fed induction generator (DFIG attracts a lot of attentions because of its efficiency and controllability. However, the DFIG is connected to the power system through inverters and originally does not have an ability to release the kinetic energy of the rotor or resorb the surplus power of the power system as the kinetic energy. Therefore, it has not been made clear how the DFIGs have an influence on small-signal stability in power systems. In this paper, we propose a control scheme of the DFIG and analyse its effect on the small-signal stability of the power system by eigenvalue calculations and time-domain simulations.

  9. Generation of uniform low-temperature plasma in a pulsed non-self-sustained glow discharge with a large-area hollow cathode

    Science.gov (United States)

    Akhmadeev, Yu. H.; Denisov, V. V.; Koval, N. N.; Kovalsky, S. S.; Lopatin, I. V.; Schanin, P. M.; Yakovlev, V. V.

    2017-01-01

    Generation of plasma in a pulsed non-self-sustained glow discharge with a hollow cathode with an area of ≥2 m2 at gas pressures of 0.4-1 Pa was studied experimentally. At an auxiliary arc-discharge current of 100 A and a main discharge voltage of 240 V, a pulse-periodic glow discharge with a current amplitude of 370 A, pulse duration of 340 μs, and repetition rate of 1 kHz was obtained. The possibility of creating a uniform gas-discharge plasma with a density of up to 1012 cm-3 and an electron temperature of 1 eV in a volume of >0.2 m3 was demonstrated. Such plasma can be efficiently used to treat material surfaces and generate pulsed ion beams with a current density of up to 15 mA/cm2.

  10. Coordinated Multi-Objective Control of Regulating Resources in Multi-Area Power Systems with Large Penetration of Wind Power Generation

    DEFF Research Database (Denmark)

    Nyeng, Preben; Yang, Bo; Ma, Jian

    2008-01-01

    This paper describes a control algorithm for a Wide Area Energy Storage and Management System (WAEMS). The WAEMS is designed to meet the demand for fast, accurate and reliable regulation services in multi-area power systems with a significant share of wind power and other intermittent generation....... The means are utilization of flywheel energy storage units, hydro power generation, and energy exchange among the participating control areas. The objective of the control algorithm is to respond to the control signals from the different system operators, whilst optimizing the hydro power plant operation...... by reducing the tear and wear on the mechanical parts and improving the energy efficiency of the plant. The performance of the WAEMS is simulated using a mathematical model, including hydro power plant and flywheel energy storage models. ACE measurements from the California ISO and Bonneville Power...

  11. A Simple Configuration for 40 Gbit/s CSRZ Signal Generation with Electrical Band-Limiting to Achieve Large Dispersion Tolerance

    Institute of Scientific and Technical Information of China (English)

    Dong-Soo; Lee; Man; Seop; Lee; Ampalavanapillai; Nirmalathas

    2003-01-01

    We present a novel configuration for carrier suppressed return-to-zero (CSRZ) signal generation, which only requires a single stage Mach-Zehnder (MZ) modulator in conjunction with an electrical mixer. Electrical band-limiting is also introduced to increase dispersion tolerance without causing additional penalty due to nonlinear effects in long haul dense wavelength division multiplexed (DWDM) CSRZ systems using conventional launch power levels.

  12. Broadband mid-infrared supercontinuum generation in 1-meter-long As2S3-based fiber with ultra-large core diameter.

    Science.gov (United States)

    Zhang, Peiqing; Yang, Peilong; Wang, Xunsi; Wang, Rongping; Dai, Shixun; Nie, Qiuhua

    2016-12-12

    In this study, the supercontinuum (SC) generation in a 1-m-long As2S3 fiber with a 200 μm core diameter was demonstrated experimentally. The high-purity As2S3 fiber we used exhibited very low optical loss with a background loss of approximately 0.1 dB/m at a wavelength of 2-5 μm. SC generation was studied by pumping the fiber at different wavelengths and different peak powers. A strong spectral broadening with a 30 dB spectral flatness spanning from 1.4 to 7.0 µm was obtained when the fiber was pumped with 150 fs short pulses at 5.0 µm. The SC generation in bent fiber was also studied. The result showed that the bending radius of the fiber will significantly affect the SC spectra bandwidth and the output power. The SC spectra in the used fiber could still be maintained when it was bent to a radius of 5 cm.

  13. How to Create a Student-Generated Database, in a Large Nutrition Class, to Illustrate the Analysis of Nutrient and Food Intakes

    Science.gov (United States)

    Gurfinkel, Debbie M.; Wolever, Thomas M. S.

    2017-01-01

    The completion of a 3-d food record, using commonly available nutrient analysis software, is a typical assignment for students in nutrition and food science programs. While these assignments help students evaluate their personal diets, it is insufficient to teach students about surveys of large population cohorts. This paper shows how the Test,…

  14. How to Create a Student-Generated Database, in a Large Nutrition Class, to Illustrate the Analysis of Nutrient and Food Intakes

    Science.gov (United States)

    Gurfinkel, Debbie M.; Wolever, Thomas M. S.

    2017-01-01

    The completion of a 3-d food record, using commonly available nutrient analysis software, is a typical assignment for students in nutrition and food science programs. While these assignments help students evaluate their personal diets, it is insufficient to teach students about surveys of large population cohorts. This paper shows how the Test,…

  15. Power Challenges of Large Scale Research Infrastructures: the Square Kilometer Array and Solar Energy Integration; Towards a zero-carbon footprint next generation telescope

    CERN Document Server

    Barbosa, Domingos; Ruiz, Valeriano; Silva, Manuel; Verdes-Montenegro, Lourdes; Santander-Vela, Juande; Maia, Dalmiro; Antón, Sonia; van Ardenne, Arnold; Vetter, Matthias; Kramer, Michael; Keller, Reinhard; Pereira, Nuno; Silva, Vitor

    2012-01-01

    The Square Kilometer Array (SKA) will be the largest Global science project of the next two decades. It will encompass a sensor network dedicated to radioastronomy, covering two continents. It will be constructed in remote areas of South Africa and Australia, spreading over 3000Km, in high solar irradiance latitudes. Solar Power supply is therefore an option to power supply the SKA and contribute to a zero carbon footprint next generation telescope. Here we outline the major characteristics of the SKA and some innovation approaches on thermal solar energy Integration with SKA prototypes.

  16. Effects of the large distribution of CdS quantum dot sizes on the charge transfer interactions into TiO2 nanotubes for photocatalytic hydrogen generation

    Science.gov (United States)

    González-Moya, Johan R.; Garcia-Basabe, Yunier; Rocco, Maria Luiza M.; Pereira, Marcelo B.; Princival, Jefferson L.; Almeida, Luciano C.; Araújo, Carlos M.; David, Denis G. F.; Ferreira da Silva, Antonio; Machado, Giovanna

    2016-07-01

    Hydrogen fuels generated by water splitting using a photocatalyst and solar irradiation are currently gaining the strength to diversify the world energy matrix in a green way. CdS quantum dots have revealed a hydrogen generation improvement when added to TiO2 materials under visible-light irradiation. In the present paper, we investigated the performance of TiO2 nanotubes coupled with CdS quantum dots, by a molecular bifunctional linker, on photocatalytic hydrogen generation. TiO2 nanotubes were obtained by anodization of Ti foil, followed by annealing to crystallize the nanotubes into the anatase phase. Afterwards, the samples were sensitized with CdS quantum dots via an in situ hydrothermal route using 3-mercaptopropionic acid as the capping agent. This sensitization technique permits high loading and uniform distribution of CdS quantum dots onto TiO2 nanotubes. The XPS depth profile showed that CdS concentration remains almost unchanged (homogeneous), while the concentration relative to the sulfate anion decreases by more than 80% with respect to the initial value after ˜100 nm in depth. The presence of sulfate anions is due to the oxidation of sulfide and occurs in greater proportion in the material surface. This protection for air oxidation inside the nanotubular matrix seemingly protected the CdS for photocorrosion in sacrificial solution leading to good stability properties proved by long duration, stable photocurrent measurements. The effect of the size and the distribution of sizes of CdS quantum dots attached to TiO2 nanotubes on the photocatalytic hydrogen generation were investigated. The experimental results showed three different behaviors when the reaction time of CdS synthesis was increased in the sensitized samples, i.e. similar, deactivation and activation effects on the hydrogen production with regard to TiO2 nanotubes. The deactivation effect was related to two populations of sizes of CdS, where the population with a shorter band gap acts as a

  17. A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly

    OpenAIRE

    Chen, Shijia; Oikonomou, Grigorios; Chiu, Cindy N.; Niles, Brett J.; Liu, Justin; Lee, Daniel A.; Antoshechkin, Igor; Prober, David A.

    2013-01-01

    Zinc-finger nucleases (ZFNs) and TAL effector nucleases (TALENs) have been shown to induce targeted mutations, but they have not been extensively tested in any animal model. Here, we describe a large-scale comparison of ZFN and TALEN mutagenicity in zebrafish. Using deep sequencing, we found that TALENs are significantly more likely to be mutagenic and induce an average of 10-fold more mutations than ZFNs. We observed a strong correlation between somatic and germ-line mutagenicity, and identi...

  18. Design and Test of the Air Motor Starting System for Large Inertia Diesel Generator Set%大惯量柴油发电机组空气马达起动系统设计及试验

    Institute of Scientific and Technical Information of China (English)

    金锋; 赵同宾; 曾凡明; 曾宪友

    2011-01-01

    Based on the special requirements of large inertia diesel generator sets,and combined with engineering practice,the air motor starting system for large inertia diesel generator set is designed.Multiple air motors are used to drive the flywheel of the dies%根据大惯量柴油发电机组的特殊要求,结合工程实践,进行了大惯量柴油发电机组起动系统的设计。采用多个压缩空气马达联合驱动柴油机飞轮进行机组的起动,经试验验证,满足设计要求。为后续的大惯量柴油发电机组起动系统设计提供了一种切实可行的方法。

  19. DEVELOPMENT OF THE AUTOMATIC TRACKING MECHANISM OF LARGE LIGHT FOCUSING DEVICES OF PHOTOVOLTAJC GENERATION%大型光伏发电聚光器跟踪机构的研制

    Institute of Scientific and Technical Information of China (English)

    许志龙

    2009-01-01

    The light focusing efficiency is largely influenced by the sun tracking accuracy of light focusing devices of pho-tovoltaic generation. The potential error of one planar tracking mechanism with friction wheel and lead screw combined was analyzed. In the test, practicality indicated which can be used in real-time tracking of the elevation angle and azi-muth angle of the sun for various kinds of large light focusing devices of photovoltaic generation.%介绍了一种摩擦轮驱动和丝杆驱动组合的二维跟踪机构,在此基础上对跟踪可能产生的误差进行分析,并通过实践验证,得出此种驱动方案适用于各种大型光伏发电聚光器实时跟踪太阳的方位角和高度角.

  20. Doppler method leak detection for LMFBR steam generators. Pt. 2. Detection characteristics of bubble in-water using large scale SG model

    Energy Technology Data Exchange (ETDEWEB)

    Kumagai, Hiromichi [Central Research Inst. of Electric Power Industry, Komae, Tokyo (Japan). Komae Research Lab

    2000-06-01

    To prevent the expansion of tube damage and to maintain structural integrity in the steam generators (SGs) of a fast breeder reactor (FBR), it is necessary to detect precisely and immediately the leakage of water from heat transfer tubes. Therefore, an active acoustic method was developed. Previous studies have revealed that, in practical steam generators, the active acoustic method can detect bubbles of 10 l/s within 10 seconds. However to prevent the expansion of damage to neighboring tubes, it is necessary to detect smaller leakages of water from the heat transfer tubes. The Doppler method is designed to detect small leakages and to find the source of a leak before damage spreads to neighboring tubes. The detection sensitivity of the Doppler method and the influence of background noise were investigated experimentally. In-water experiments were performed using an SG full-sector model that simulates actual SGs. The results show that the Doppler method can detect bubbles of 0.1 l/s (equivalent to a water leak rate of about 0.1 g/s) within a few seconds and that the background noise has little effect on water leak detection performance. The Doppler method thus has great potential for the detection of water leakage in SGs. (author)

  1. Magnetocumulative generator

    Science.gov (United States)

    Pettibone, J.S.; Wheeler, P.C.

    1981-06-08

    An improved magnetocumulative generator is described that is useful for producing magnetic fields of very high energy content over large spatial volumes. The polar directed pleated magnetocumulative generator has a housing providing a housing chamber with an electrically conducting surface. The chamber forms a coaxial system having a small radius portion and a large radius portion. When a magnetic field is injected into the chamber, from an external source, most of the magnetic flux associated therewith positions itself in the small radius portion. The propagation of an explosive detonation through high-explosive layers disposed adjacent to the housing causes a phased closure of the chamber which sweeps most of the magnetic flux into the large radius portion of the coaxial system. The energy content of the magnetic field is greatly increased by flux stretching as well as by flux compression. The energy enhanced magnetic field is utilized within the housing chamber itself.

  2. Performances of a large mass ZnMoO4 scintillating bolometer for a next generation neutrinoless double beta decay experiment

    CERN Document Server

    Beeman, J W; Brofferio, C; Cardani, L; Casali, N; Cremonesi, O; Dafinei, I; Di Domizio, S; Ferroni, F; Gorello, E; Galashov, E N; Gironi, L; Nagorny, S S; Orio, F; Pavan, M; Pattavina, L; Pessina, G; Piperno, G; Pirro, S; Previtali, E; Rusconi, C; Shlegel, V N; Tomei, C; Vignati, M

    2012-01-01

    We present the performances of a 330 g zinc molybdate (ZnMoO4) crystal working as scintillating bolometer as a possible candidate for a next generation experiment to search for neutrinoless double beta decay of 100Mo. The energy resolution, evaluated at the 2615 keV gamma-line of 208Tl, is 6.3 keV FWHM. The internal radioactive contaminations of the ZnMoO4 were evaluated as <6 microBq/kg (228Th) and 27\\pm6 microBq/kg (226Ra). We also present the results of the alpha vs beta/gamma discrimination, obtained through the scintillation light as well as through the study of the shape of the thermal signal alone.

  3. Analysis/plot generation code with significance levels computed using Kolmogorov-Smirnov statistics valid for both large and small samples

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, S.E.; Fields, D.E.

    1983-10-01

    This report describes a version of the TERPED/P computer code that is very useful for small data sets. A new algorithm for determining the Kolmogorov-Smirnov (KS) statistics is used to extend program applicability. The TERPED/P code facilitates the analysis of experimental data and assists the user in determining its probability distribution function. Graphical and numerical tests are performed interactively in accordance with the user's assumption of normally or log-normally distributed data. Statistical analysis options include computation of the chi-square statistic and the KS one-sample test statistic and the corresponding significance levels. Cumulative probability plots of the user's data are generated either via a local graphics terminal, a local line printer or character-oriented terminal, or a remote high-resolution graphics device such as the FR80 film plotter or the Calcomp paper plotter. Several useful computer methodologies suffer from limitations of their implementations of the KS nonparametric test. This test is one of the more powerful analysis tools for examining the validity of an assumption about the probability distribution of a set of data. KS algorithms are found in other analysis codes, including the Statistical Analysis Subroutine (SAS) package and earlier versions of TERPED. The inability of these algorithms to generate significance levels for sample sizes less than 50 has limited their usefulness. The release of the TERPED code described herein contains algorithms to allow computation of the KS statistic and significance level for data sets of, if the user wishes, as few as three points. Values computed for the KS statistic are within 3% of the correct value for all data set sizes.

  4. Next generation non-vacuum, maskless, low temperature nanoparticle ink laser digital direct metal patterning for a large area flexible electronics.

    Science.gov (United States)

    Yeo, Junyeob; Hong, Sukjoon; Lee, Daehoo; Hotz, Nico; Lee, Ming-Tsang; Grigoropoulos, Costas P; Ko, Seung Hwan

    2012-01-01

    Flexible electronics opened a new class of future electronics. The foldable, light and durable nature of flexible electronics allows vast flexibility in applications such as display, energy devices and mobile electronics. Even though conventional electronics fabrication methods are well developed for rigid substrates, direct application or slight modification of conventional processes for flexible electronics fabrication cannot work. The future flexible electronics fabrication requires totally new low-temperature process development optimized for flexible substrate and it should be based on new material too. Here we present a simple approach to developing a flexible electronics fabrication without using conventional vacuum deposition and photolithography. We found that direct metal patterning based on laser-induced local melting of metal nanoparticle ink is a promising low-temperature alternative to vacuum deposition- and photolithography-based conventional metal patterning processes. The "digital" nature of the proposed direct metal patterning process removes the need for expensive photomask and allows easy design modification and short turnaround time. This new process can be extremely useful for current small-volume, large-variety manufacturing paradigms. Besides, simple, scalable, fast and low-temperature processes can lead to cost-effective fabrication methods on a large-area polymer substrate. The developed process was successfully applied to demonstrate high-quality Ag patterning (2.1 µΩ·cm) and high-performance flexible organic field effect transistor arrays.

  5. Large Scale Generation and Characterization of Anti-Human IgA Monoclonal Antibody in Ascitic Fluid of Balb/c Mice

    Directory of Open Access Journals (Sweden)

    Fatemeh Ezzatifar

    2015-03-01

    Full Text Available Purpose: Monoclonal antibodies are potentially powerful tools used in biomedical research, diagnosis, and treatment of infectious diseases and cancers. The monoclonal antibody against Human IgA can be used as a diagnostic application to detect infectious diseases. The aim of this study was to improve an appropriate protocol for large-scale production of mAbs against IgA. Methods: For large-scale production of the monoclonal antibody, hybridoma cells that produce monoclonal antibodies against Human IgA were injected intraperitoneally into Balb/c mice that were previously primed with 0.5 ml Pristane. After ten days, ascitic fluid was harvested from the peritoneum of each mouse. The ELISA method was carried out for evaluation of the titration of produced mAbs. The ascitic fluid was investigated in terms of class and subclass by a mouse mAb isotyping kit. MAb was purified from the ascitic fluid by ion exchange chromatography. The purity of the monoclonal antibody was confirmed by SDS-PAGE, and the purified monoclonal antibody was conjugated with HRP. Results: Monoclonal antibodies with high specificity and sensitivity against Human IgA were prepared by hybridoma technology. The subclass of antibody was IgG1 and its light chain was the kappa type. Conclusion: This conjugated monoclonal antibody could have applications in designing ELISA kits in order to diagnose different infectious diseases such as toxoplasmosis and H. Pylori.

  6. Generation of dual-wavelength square pulse in a figure-eight erbium-doped fiber laser with ultra-large net-anomalous dispersion.

    Science.gov (United States)

    Shao, Zhihua; Qiao, Xueguang; Rong, Qiangzhou; Su, Dan

    2015-08-01

    A type of wave-breaking-free mode-locked dual-wavelength square pulse was experimentally observed in a figure-eight erbium-doped fiber laser with ultra-large net-anomalous dispersion. A 2.7 km long single-mode fiber (SMF) was incorporated as a nonlinear optical loop mirror (NOLM) and provided largely nonlinear phase accumulation and anomalous dispersion, which enhanced the four-wave-mixing effect to improve the stability of the dual-wavelength operation. In the NOLM, the long SMF with small birefringence supported the Sagnac interference as a filter to manage the dual-wavelength lasing. The dual-wavelength operation was made switchable by adjusting the intra-cavity polarization loss and phase delay corresponding to two square pulses. When the pump power was increased, the duration of the square pulse increased continuously while the peak pulse power gradually decreased. This square-type pulse can potentially be utilized for signal transmission and sensing.

  7. Next generation non-vacuum, maskless, low temperature nanoparticle ink laser digital direct metal patterning for a large area flexible electronics.

    Directory of Open Access Journals (Sweden)

    Junyeob Yeo

    Full Text Available Flexible electronics opened a new class of future electronics. The foldable, light and durable nature of flexible electronics allows vast flexibility in applications such as display, energy devices and mobile electronics. Even though conventional electronics fabrication methods are well developed for rigid substrates, direct application or slight modification of conventional processes for flexible electronics fabrication cannot work. The future flexible electronics fabrication requires totally new low-temperature process development optimized for flexible substrate and it should be based on new material too. Here we present a simple approach to developing a flexible electronics fabrication without using conventional vacuum deposition and photolithography. We found that direct metal patterning based on laser-induced local melting of metal nanoparticle ink is a promising low-temperature alternative to vacuum deposition- and photolithography-based conventional metal patterning processes. The "digital" nature of the proposed direct metal patterning process removes the need for expensive photomask and allows easy design modification and short turnaround time. This new process can be extremely useful for current small-volume, large-variety manufacturing paradigms. Besides, simple, scalable, fast and low-temperature processes can lead to cost-effective fabrication methods on a large-area polymer substrate. The developed process was successfully applied to demonstrate high-quality Ag patterning (2.1 µΩ·cm and high-performance flexible organic field effect transistor arrays.

  8. Large Mesopore Generation in an Amorphous Silica-Alumina by Controlling the Pore Size with the Gel Skeletal Reinforcement and Its Application to Catalytic Cracking

    Directory of Open Access Journals (Sweden)

    Hiroyuki Nasu

    2012-09-01

    Full Text Available Tetraethoxy orthosilicate (TEOS was used not only as a precursor of silica, but also as an agent which reinforces the skeleton of silica-gel to prepare an aerogel and resultant silica and silica-alumina with large pore size and pore volume. In this gel skeletal reinforcement, the strength of silica aerogel skeleton was enhanced by aging with TEOS/2-propanol mixed solution to prevent the shrink of the pores. When silica aerogel was reinforced by TEOS solution, the pore diameter and pore volume of calcined silica could be controlled by the amount of TEOS solution and reached 30 nm and 3.1 cm3/g. The results from N2 adsorption measurement indicated that most of pores for this silica consisted of mesopores. Silica-alumina was prepared by the impregnation of an aluminum tri-sec-butoxide/2-butanol solution with obtained silica. Mixed catalysts were prepared by the combination of β-zeolite (26 wt% and prepared silica-aluminas with large mesopore (58 wt% and subsequently the effects of their pore sizes on the catalytic activity and the product selectivity were investigated in catalytic cracking of n-dodecane at 500 °C. The mixed catalysts exhibited not only comparable activity to that for single zeolite, but also unique selectivity where larger amounts of branched products were formed.

  9. Next-generation radio telescope of the 12- to 15-m class for the future large-interferometer arrays in the southern hemisphere

    Science.gov (United States)

    Plathner, Dietmar E.

    1998-07-01

    Based on the quality proven technologies applied on the IRAM 15 m Plateau de Bure telescopes strategies have been developed to design antennas for the future large arrays in the southern hemisphere which shall operate at frequencies as high as 850 GHz and have a very large collecting area. For this type of antenna space frames were applied wherever possible as the full cross-section of their push-pull members is used for load transfer. Thus giving maximum stiffness at minimum weight to the proposed telescope structures. The lowest eigenfrequency is therefore predicted to be in the order of 12 Hz. Similar high performances are expected under the specified windloads at the chosen site in the Atacama Desert probably at an altitude of 5000 m. Such an exposed location requires simple, low maintenance telescopes despite of their high performance requirements, so that e.g. all active thermal stabilization is avoided by the use of low expansion carbon fiber composite material for critical members. Finally an opto-mechanical metrology system is applied which replaces the standard 'on- bord' encoders and makes the control of the telescopes independent of structural deformations in the mount. An overall surface error of 25 micrometer rms for a 12 to 15 m class telescope can be obtained and the resulting pointing error under wind load is in the order of 0.4 arcsec.

  10. Large-area homogeneous periodic surface structures generated on the surface of sputtered boron carbide thin films by femtosecond laser processing

    Energy Technology Data Exchange (ETDEWEB)

    Serra, R., E-mail: ricardo.serra@dem.uc.pt [SEG-CEMUC, Mechanical Engineering Department, University of Coimbra, Rua Luís Reis Santos, 3030-788 Coimbra (Portugal); Oliveira, V. [ICEMS-Instituto de Ciência e Engenharia de Materiais e Superfícies, Avenida Rovisco Pais no 1, 1049-001 Lisbon (Portugal); Instituto Superior de Engenharia de Lisboa, Avenida Conselheiro Emídio Navarro no 1, 1959-007 Lisbon (Portugal); Oliveira, J.C. [SEG-CEMUC, Mechanical Engineering Department, University of Coimbra, Rua Luís Reis Santos, 3030-788 Coimbra (Portugal); Kubart, T. [The Ångström Laboratory, Solid State Electronics, P.O. Box 534, SE-751 21 Uppsala (Sweden); Vilar, R. [Instituto Superior de Engenharia de Lisboa, Avenida Conselheiro Emídio Navarro no 1, 1959-007 Lisbon (Portugal); Instituto Superior Técnico, Avenida Rovisco Pais no 1, 1049-001 Lisbon (Portugal); Cavaleiro, A. [SEG-CEMUC, Mechanical Engineering Department, University of Coimbra, Rua Luís Reis Santos, 3030-788 Coimbra (Portugal)

    2015-03-15

    Highlights: • Large-area LIPSS were formed by femtosecond laser processing B-C films surface. • The LIPSS spatial period increases with laser fluence (140–200 nm). • Stress-related sinusoidal-like undulations were formed on the B-C films surface. • The undulations amplitude (down to a few nanometres) increases with laser fluence. • Laser radiation absorption increases with surface roughness. - Abstract: Amorphous and crystalline sputtered boron carbide thin films have a very high hardness even surpassing that of bulk crystalline boron carbide (≈41 GPa). However, magnetron sputtered B-C films have high friction coefficients (C.o.F) which limit their industrial application. Nanopatterning of materials surfaces has been proposed as a solution to decrease the C.o.F. The contact area of the nanopatterned surfaces is decreased due to the nanometre size of the asperities which results in a significant reduction of adhesion and friction. In the present work, the surface of amorphous and polycrystalline B-C thin films deposited by magnetron sputtering was nanopatterned using infrared femtosecond laser radiation. Successive parallel laser tracks 10 μm apart were overlapped in order to obtain a processed area of about 3 mm{sup 2}. Sinusoidal-like undulations with the same spatial period as the laser tracks were formed on the surface of the amorphous boron carbide films after laser processing. The undulations amplitude increases with increasing laser fluence. The formation of undulations with a 10 μm period was also observed on the surface of the crystalline boron carbide film processed with a pulse energy of 72 μJ. The amplitude of the undulations is about 10 times higher than in the amorphous films processed at the same pulse energy due to the higher roughness of the films and consequent increase in laser radiation absorption. LIPSS formation on the surface of the films was achieved for the three B-C films under study. However, LIPSS are formed under

  11. Analysis of large scale photovoltaic power generation network impact on power system%分析大规模光伏发电入网对电力系统的影响

    Institute of Scientific and Technical Information of China (English)

    李娟

    2015-01-01

    本文从大规模光伏发电入网的内涵和建模两个方面对大规模光伏发电入网进行了阐述,着重分析了大规模光伏发电入网对电力系统的影响,从而为我国的光伏发电产业的发展奠定坚实的基础。%In this paper,from two aspects of the connotation and modeling of large-scale photovoltaic power network of large-scale photovoltaic power network are described, focuses on the analysis of the large-scale photovoltaic power generation network influence on the power system, so as to lay a solid foundation for development of the PV industry in our country.

  12. Present and Future of Semiconductor Pulsed Power Generator ˜Role of Power Semiconductor Devices in Plasma Research˜ 6.High-Speed, Large-Current Power Semiconductors for Pulse Power Generation

    Science.gov (United States)

    Takata, Ikunori

    This paper describes the operation principles and limits of power semiconductors. In addition, operation mechanisms of the new pulse power devices, SOS (Semiconductor Opening Switch) and dynistors, are explained qualitatively. The fastest operating power device is the series connection of comparatively low-voltage devices. For large-current operation, a uniformly operating pin-diode structure device is essential. An SOS is constructed from dozens of medium voltage (about 3kV) special hard-recovery diodes. This can shut off 2kA current at 10kV with in 10ns. The dynistor has n+pnp+ four layers and two electrodes. Serial-connected dynistors have the potential to replace thyratrons. These new devices can endure over 10 kA/cm2 at much higher voltage than their static breakdown values in the repetitive use more than 1011 times.

  13. 2D THD and 3D TEHD analysis of large spindle supported thrust bearings with pins and double layer system used in the three gorges hydroelectric generators

    Science.gov (United States)

    Huang, B.; Wu, Z. D.; Wu, J. L.; Wang, L. Q.

    2012-11-01

    A 2D THD model and a 3DTEHD model for large spindle supported thrust bearings were set up and used to analyze the lubrication performance of the Three Gorges test thrust beating withpins and double layer system developed by Alstom Power. The finite difference method was employed to solve the THD model, and the thermal-elasticdeformations in the pad and runner were obtained by the finite element software ANSYS11.0. The data transfer between the THD model and ANSYS11.0 was carried out automatically by an interface program.A detailed comparison between the experimental results and numerical predictions by the two different modelsset up in this paper was carried out. Poor agreement has been found between the theoretical results obtained by 2D THD model and experimental data, while 3D TEHD provides fairly good agreement, confirming the importance of thermal effects and thermal-elastic deformations in both pad and runner.

  14. Use of second-generation platelet concentrate (platelet-rich fibrin) and hydroxyapatite in the management of large periapical inflammatory lesion: a computed tomography scan analysis.

    Science.gov (United States)

    Hiremath, Hemalatha; Motiwala, Tejas; Jain, Pradeep; Kulkarni, Sadanand

    2014-01-01

    Periapical surgery is required when periradicular pathosis associated with endodontically treated teeth cannot be resolved by nonsurgical root canal therapy (retreatment), or when retreatment was unsuccessful, not feasible or contraindicated. Endodontic failures can occur when irritants remain within the confines of the root canal, or when an extraradicular infection cannot be eradicated by orthograde root canal treatment. Foreign-body responses toward filling materials, toward cholesterol crystals or radicular cysts, might prevent complete periapical healing. We present here a case report wherein, combination of platelet-rich fibrin (PRF) and the hydroxyapatite graft was used to achieve faster healing of the large periapical lesion. Healing was observed within 8 months, which were confirmed by computed tomography, following improved bone density. PRF has many advantages over platelet-rich plasma. It provides a physiologic architecture that is very favorable to the healing process, which is obtained due to the slow polymerization process.

  15. Efficient high-power generation of visible and mid-infrared light by degenerate four-wave-mixing in a large-mode-area photonic-crystal fiber.

    Science.gov (United States)

    Nodop, D; Jauregui, C; Schimpf, D; Limpert, J; Tünnermann, A

    2009-11-15

    An efficient and simple approach for converting pulsed near-IR laser radiation into visible and mid-IR light by exploiting degenerate four-wave-mixing in an endlessly single-mode, large-mode-area photonic-crystal fiber is presented. Coupling a 1 MHz, 200 ps, 8 W average power pulsed source emitting at 1064 nm into this fiber results in average powers of 3 W at 673 nm signal wavelength and of 450 mW at 2539 nm idler wavelength, respectively. The excellent pulse energy conversion efficiencies of 35% for the signal and 6% for the idler wavelength are due to the unique combination of characteristics of this type of fiber.

  16. Use of second-generation platelet concentrate (platelet-rich fibrin and hydroxyapatite in the management of large periapical inflammatory lesion: A computed tomography scan analysis

    Directory of Open Access Journals (Sweden)

    Hemalatha Hiremath

    2014-01-01

    Full Text Available Periapical surgery is required when periradicular pathosis associated with endodontically treated teeth cannot be resolved by nonsurgical root canal therapy (retreatment, or when retreatment was unsuccessful, not feasible or contraindicated. Endodontic failures can occur when irritants remain within the confines of the root canal, or when an extraradicular infection cannot be eradicated by orthograde root canal treatment. Foreign-body responses toward filling materials, toward cholesterol crystals or radicular cysts, might prevent complete periapical healing. We present here a case report wherein, combination of platelet-rich fibrin (PRF and the hydroxyapatite graft was used to achieve faster healing of the large periapical lesion. Healing was observed within 8 months, which were confirmed by computed tomography, following improved bone density. PRF has many advantages over platelet-rich plasma. It provides a physiologic architecture that is very favorable to the healing process, which is obtained due to the slow polymerization process.

  17. Potential large scale generation of electricity with wind energy in Mexico; Potencial de generacion electrica en gran escala con energia eolica en Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Caldera Munoz, Enrique

    1997-12-31

    The technology of wind-electric stations for the conversion of wind-power into electricity massively generated and interconnected to the National electric systems is nowadays a mature technology. By the end of 1995 the world had an installed capacity in operation of 5,000 MW and what had been planned for year 2000 was to complete an installed capacity in operation 13,800 MW, in accordance with a Riso National Laboratory of Denmark study of 1995. This document describes the current status of this technology in Mexico, as well as the historic evolution of the electric sector [Espanol] La tecnologia de centrales eoloelectricas para la conversion de energia eolica a electricidad, generada masivamente e interconectada a los sistemas electricos nacionales, es en la actualidad una tecnologia madura. A finales de 1995 en el mundo habia una capacidad instalada en operacion de 5,000 MW y lo que se habia planificado para el ano 2000 eran completar en operacion 13,800 MW, segun encuesta realizada por Riso National Laboratory de Dinamarca en 1995. Este documento describe el estado actual de esta tecnologia en Mexico, asi como la evolucion historica del sector electrico

  18. Assessment of generic solar thermal systems for large power applications: analysis of electric power generating costs for systems larger than 10 MWe

    Energy Technology Data Exchange (ETDEWEB)

    Apley, W.J.; Bird, S.P.; Brown, D.R.; Drost, M.K.; Fort, J.A.; Garrett-Price, B.A.; Patton, W.P.; Williams, T.A.

    1980-11-01

    Seven generic types of collectors, together with associated subsystems for electric power generation, were considered. The collectors can be classified into three categories: (1) two-axis tracking (with compound-curvature reflecting surfaces); (2) one-axis tracking (with single-curvature reflecting surfaces); and (3) nontracking (with low-concentration reflecting surfaces). All seven collectors were analyzed in conceptual system configurations with Rankine-cycle engines. In addition, two of the collectors were analyzed with Brayton-cycle engines, and one was analyzed with a Stirling-cycle engine. With these engine options, and the consideration of both thermal and electrical storage for the Brayton-cycle central receiver, 11 systems were formulated for analysis. Conceptual designs developed for the 11 systems were based on common assumptions of available technology in the 1990 to 2000 time frame. No attempt was made to perform a detailed optimization of each conceptual design. Rather, designs best suited for a comparative evaluation of the concepts were formulated. Costs were estimated on the basis of identical assumptions, ground rules, methodologies, and unit costs of materials and labor applied uniformly to all of the concepts. The computer code SOLSTEP was used to analyze the thermodynamic performance characteristics and energy costs of the 11 concepts. Year-long simulations were performed using meteorological and insolation data for Barstow, California. Results for each concept include levelized energy costs and capacity factors for various combinations of storage capacity and collector field size.

  19. Large-area homogeneous periodic surface structures generated on the surface of sputtered boron carbide thin films by femtosecond laser processing

    Science.gov (United States)

    Serra, R.; Oliveira, V.; Oliveira, J. C.; Kubart, T.; Vilar, R.; Cavaleiro, A.

    2015-03-01

    Amorphous and crystalline sputtered boron carbide thin films have a very high hardness even surpassing that of bulk crystalline boron carbide (≈41 GPa). However, magnetron sputtered B-C films have high friction coefficients (C.o.F) which limit their industrial application. Nanopatterning of materials surfaces has been proposed as a solution to decrease the C.o.F. The contact area of the nanopatterned surfaces is decreased due to the nanometre size of the asperities which results in a significant reduction of adhesion and friction. In the present work, the surface of amorphous and polycrystalline B-C thin films deposited by magnetron sputtering was nanopatterned using infrared femtosecond laser radiation. Successive parallel laser tracks 10 μm apart were overlapped in order to obtain a processed area of about 3 mm2. Sinusoidal-like undulations with the same spatial period as the laser tracks were formed on the surface of the amorphous boron carbide films after laser processing. The undulations amplitude increases with increasing laser fluence. The formation of undulations with a 10 μm period was also observed on the surface of the crystalline boron carbide film processed with a pulse energy of 72 μJ. The amplitude of the undulations is about 10 times higher than in the amorphous films processed at the same pulse energy due to the higher roughness of the films and consequent increase in laser radiation absorption. LIPSS formation on the surface of the films was achieved for the three B-C films under study. However, LIPSS are formed under different circumstances. Processing of the amorphous films at low fluence (72 μJ) results in LIPSS formation only on localized spots on the film surface. LIPSS formation was also observed on the top of the undulations formed after laser processing with 78 μJ of the amorphous film deposited at 800 °C. Finally, large-area homogeneous LIPSS coverage of the boron carbide crystalline films surface was achieved within a large range

  20. Observing Exoplanets with High Dispersion Coronagraphy. I. The Scientific Potential of Current and Next-generation Large Ground and Space Telescopes

    Science.gov (United States)

    Wang, Ji; Mawet, Dimitri; Ruane, Garreth; Hu, Renyu; Benneke, Björn

    2017-04-01

    Direct imaging of exoplanets presents a formidable technical challenge owing to the small angular separation and high contrast between exoplanets and their host stars. High Dispersion Coronagraphy (HDC) is a pathway to achieve unprecedented sensitivity to Earth-like planets in the habitable zone. Here, we present a framework to simulate HDC observations and data analyses. The goal of these simulations is to perform a detailed analysis of the trade-off between raw star light suppression and spectral resolution for various instrument configurations, target types, and science cases. We predict the performance of an HDC instrument at Keck observatory for characterizing directly imaged gas-giant planets in near-infrared bands. We also simulate HDC observations of an Earth-like planet using next-generation ground-based (TMT) and spaced-base telescopes (HabEx and LUVOIR). We conclude that ground-based ELTs are more suitable for HDC observations of an Earth-like planet than future space-based missions owing to the considerable difference in collecting area. For ground-based telescopes, HDC observations can detect an Earth-like planet in the habitable zone around an M-dwarf star at 10-4 star light suppression level. Compared to the 10-7 planet/star contrast, HDC relaxes the star light suppression requirement by a factor of 103. For space-based telescopes, detector noise will be a major limitation at spectral resolutions higher than 104. Considering detector noise and speckle chromatic noise, R = 400 (1600) is the optimal spectral resolutions for HabEx (LUVOIR). The corresponding star light suppression requirement to detect a planet with planet/star contrast = 6.1× {10}-11 is relaxed by a factor of 10 (100) for HabEx (LUVOIR).

  1. Activating somatic mutations in diffuse large B-cell lymphomas: lessons from next generation sequencing and key elements in the precision medicine era.

    Science.gov (United States)

    Bohers, Elodie; Mareschal, Sylvain; Bertrand, Philippe; Viailly, Pierre Julien; Dubois, Sydney; Maingonnat, Catherine; Ruminy, Philippe; Tilly, Hervé; Jardin, Fabrice

    2015-05-01

    Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma, accounting for 30-40% of newly diagnosed non-Hodgkin lymphomas. Historically, DLBCL has been thought to involve recurrent translocations of the immunoglobulin heavy (IGH) locus and the deregulation of rearranged oncogenes. Whole exome sequencing (WES) of more than 200 DLBCLs has completely redefined the genetic landscape of the disease by identifying recurrent single nucleotide variants and providing new therapeutic opportunities in DLBCL molecular subtypes. Some of these somatic mutations target genes that play a crucial role in B-cell function (B cell receptor [BCR] signaling, nuclear factor κB [NF-κB] pathway, Toll-like receptor [TLR] signaling and phosphatidylinositol 3-kinase [PI3K] pathway), immunity, cell cycle/apoptosis or chromatin modification. In this review, following an overview of the somatic mutations reported in DLBCL, we focus on activating and clustered mutations targeting genes including MYD88, CD79A/B, EZH2 and CARD11 and discuss their clinical and therapeutic relevance in the precision medicine era.

  2. An Automatic Mosaicking Algorithm for the Generation of a Large-Scale Forest Height Map Using Spaceborne Repeat-Pass InSAR Correlation Magnitude

    Directory of Open Access Journals (Sweden)

    Yang Lei

    2015-05-01

    Full Text Available This paper describes an automatic mosaicking algorithm for creating large-scale mosaic maps of forest height. In contrast to existing mosaicking approaches through using SAR backscatter power and/or InSAR phase, this paper utilizes the forest height estimates that are inverted from spaceborne repeat-pass cross-pol InSAR correlation magnitude. By using repeat-pass InSAR correlation measurements that are dominated by temporal decorrelation, it has been shown that a simplified inversion approach can be utilized to create a height-sensitive measure over the whole interferometric scene, where two scene-wide fitting parameters are able to characterize the mean behavior of the random motion and dielectric changes of the volume scatterers within the scene. In order to combine these single-scene results into a mosaic, a matrix formulation is used with nonlinear least squares and observations in adjacent-scene overlap areas to create a self-consistent estimate of forest height over the larger region. This automated mosaicking method has the benefit of suppressing the global fitting error and, thus, mitigating the “wallpapering” problem in the manual mosaicking process. The algorithm is validated over the U.S. state of Maine by using InSAR correlation magnitude data from ALOS/PALSAR and comparing the inverted forest height with Laser Vegetation Imaging Sensor (LVIS height and National Biomass and Carbon Dataset (NBCD basal area weighted (BAW height. This paper serves as a companion work to previously demonstrated results, the combination of which is meant to be an observational prototype for NASA’s DESDynI-R (now called NISAR and JAXA’s ALOS-2 satellite missions.

  3. Mycoplasma pneumonia of swine (MPS) resistance and immune characteristics of pig lines generated by crossing an MPS pulmonary lesion selected Landrace line and a highly immune capacity selected Large White line.

    Science.gov (United States)

    Borjigin, Liushiqi; Shimazu, Tomoyuki; Katayama, Yuki; Watanabe, Kouichi; Kitazawa, Haruki; Roh, Sang-Gun; Aso, Hisashi; Katoh, Kazuo; Uchida, Takafumi; Suda, Yoshihito; Sakuma, Akiko; Nakajo, Mituru; Suzuki, Keiichi

    2016-08-01

    To understand the influence of crossbreeding on Mycoplasma pneumonia of swine (MPS) resistance and immune characteristics, two crossbred lines were characterized. One crossbred line, LaWa, was generated by crossing the MPS pulmonary lesion selected Landrace line (La) and the highly immune-selected Large White line (Wa). The second crossbred line, LaWb, was generated by crossing the La line and the nonselected Large White line (Wb). The crossbred LbWb line (nonselected Landrace line × nonselected Large White line) and the La line were used as controls. The LaWa and LaWb lines had an intermediate level of MPS lung lesions between La and LbWb lines, although the difference was not statistically significant. After stimulation with sheep red blood cells (SRBCs), the LaWb and LaWa lines showed immune characteristics similar to that of the La line; the number of monocytes in peripheral blood increased, while B cells, T cells, secretion of SRBC-specific immunoglobulin G, and interleukin (IL)-13 decreased. Additionally, the number of natural killer (NK) cells and the expression of IL-4 and IL-17 were significantly higher in the LaWb and LaWa lines, respectively. These data suggested that crossbreeding of La and Wa lines resulted in the inheritance of some of the selected immune responses. © 2015 Japanese Society of Animal Science.

  4. Generation of a restriction minus enteropathogenic Escherichia coli E2348/69 strain that is efficiently transformed with large, low copy plasmids

    Directory of Open Access Journals (Sweden)

    Ward Jordan D

    2008-08-01

    Full Text Available Abstract Background Many microbes possess restriction-modification systems that protect them from parasitic DNA molecules. Unfortunately, the presence of a restriction-modification system in a given microbe also hampers genetic analysis. Although plasmids can be successfully conjugated into the enteropathogenic Escherichia coli strain E2348/69 and optimized protocols for competent cell preparation have been developed, we found that a large, low copy (~15 bioluminescent reporter plasmid, pJW15, that we modified for use in EPEC, was exceedingly difficult to transform into E2348/69. We reasoned that a restriction-modification system could be responsible for the low transformation efficiency of E2348/69 and sought to identify and inactivate the responsible gene(s, with the goal of creating an easily transformable strain of EPEC that could complement existing protocols for genetic manipulation of this important pathogen. Results Using bioinformatics, we identified genes in the unfinished enteropathogenic Escherichia coli (EPEC strain E2348/69 genome whose predicted products bear homology to the HsdM methyltransferases, HsdS specificity subunits, and HsdR restriction endonucleases of type I restriction-modification systems. We constructed a strain carrying a deletion of the conserved enzymatic domain of the EPEC HsdR homologue, NH4, and showed that its transformation efficiency was up to four orders of magnitude higher than that of the parent strain. Further, the modification capacity of NH4 remained intact, since plasmids that were normally recalcitrant to transformation into E2348/69 could be transformed upon passage through NH4. NH4 was unaffected in virulence factor production, since bundle forming pilus (BFP subunits and type III secreted (T3S proteins were present at equivalent levels to those seen in E2348/69. Further, NH4 was indistinguishable from E2348/69 in tissue culture infection model assays of localized adherence and T3S. Conclusion We

  5. Brief Analysis on Design of Assorted Diesel Generator System for Large Data Center%大型数据中心配套柴油发电机系统设计简析

    Institute of Scientific and Technical Information of China (English)

    严俊

    2015-01-01

    结合实际工程案例,从供配电系统、柴油发电机组的启动控制、供油系统及测试负载选择等方面简要阐述大型数据中心配套柴油发电机房设计的心得和体会。%The experience in designing assorted diesel generator system for a large data center is briefly summarized from the aspects such as the power supply and distribution system, the start control of the diesel generator set, selection of the oil supply system and test load by combining actual project case.

  6. Large N

    CERN Document Server

    Hooft, G

    2002-01-01

    In the first part of this lecture, the 1/N expansion technique is illustrated for the case of the large-N sigma model. In large-N gauge theories, the 1/N expansion is tantamount to sorting the Feynman diagrams according to their degree of planarity, that is, the minimal genus of the plane onto which the diagram can be mapped without any crossings. This holds both for the usual perturbative expansion with respect to powers of {tilde g}^2=g^2 N, as well as for the expansion of lattice theories in positive powers of 1/{tilde g}^2. If there were no renormalization effects, the tilde g expansion would have a finite radius of convergence. The zero-dimensional theory can be used for counting planar diagrams. It can be solved explicitly, so that the generating function for the number of diagrams with given 3-vertices and 4-vertices, can be derived exactly. This can be done for various kinds of Feynman diagrams. We end with some remarks about planar renormalization.

  7. A Review on the Effect of Large-scale PV Generation on Power Systems%大规模光伏发电对电力系统影响综述

    Institute of Scientific and Technical Information of China (English)

    丁明; 王伟胜; 王秀丽; 宋云亭; 陈得治; 孙鸣

    2014-01-01

    Because of human concern for energy security and environmental deterioration, making full use of renewable energy has been a global consensus. Power generation with large-scale renewable energy such as solar and wind energy has become the development trend of new power systems, resulting in increasingly prominent impact on power systems. Therefore, great concerns are given from academic and engineering areas of all countries. The purpose of this paper is to review the globe status of large-scale photovoltaic (PV) power generation, explore the factors affecting the interaction between solar power generation and power system, refine academic and engineering problems, and propose ideas for future research and development. From the perspective of power system planning, simulation, dispatching and control, this paper discusses the modeling and simulation of large-scale photovoltaic power generation, impacts of large scale PV integration on dynamic and static characteristics of power system, and key technologies about large scale PV power generation delivery and consumption. Meanwhile, suggestions for further research are proposed from the authors’ point of view, offering reference for readers.%人类对能源安全的担忧和环境恶化的焦虑,使得充分利用可再生能源已经成为全球共识。以太阳能、风能为代表的大规模可再生能源并网发电已经成为新型电力系统不可阻挡的发展趋势,对电力系统深层次的影响正在凸显,各国学术界和工程界均给予极大关注。该文的目的,在于综述国内外大规模光伏发电研究现状,探究光伏发电与电力系统间交互影响的因素,提炼存在的学术和工程问题,理清下一步研发思路。论文从电力系统规划、仿真、调度、控制角度,重点讨论了大规模光伏系统的建模与仿真、大规模光伏接入对系统动态和稳态特性的影响、大规模光伏外送及消纳的关键技术分析;

  8. 大容量SF6发电机断路器关键技术的探讨%Discussion on the Key Technologies of Large Capacity SF6 Generator Circuit Breaker

    Institute of Scientific and Technical Information of China (English)

    徐齐巍

    2015-01-01

    针对我国电力事业需求及国内发电机断路器的技术水平,阐述国内发电机断路器的发展趋势和迫切目标,提出推进国内发电机断路器发展进程的关键点;通过引入国际先进理念,探讨大容量SF6发电机断路器的关键技术,在结构型式、灭弧原理、特殊性能指标、冷却方式、操动机构方面进行深入研究,并针对该关键技术的难点问题提出解决思路,为研发满足60万kW以上至100万kW机组要求的额定短路电流160 kA以上的大容量、高参数、运行可靠的SF6发电机断路器提供理论依据。%Based on the demand of electric undertaking in china and the technological level of national generator circuit breaker , the development trend and the exigent goal are expounded, and the cores of furthering development course for national generator circuit breaker is put forward. Through importing international advanced ideas, the key technologies of large capacity SF6 generator circuit breaker are discussed. An embedded research in respects of construction form, arc interruption principle, special performance target, cooling type and operating mechanism is made, solving ideas are provided in allusion to the difficulties in key technologies, and theoretical basis is supplied for researching large capacity SF6 generator circuit breaker with rated short-circuit current being upwards of 160 kA, and with high parameter and running reliability in order to settle for the demand of the generating units with a capacity of 600 MW up to 1 000 MW.

  9. Research on Dynamic Behavior of Frame Foundation for Large-Scale Steam Turbine-Generator Set%大型汽轮发电机组框架式基础的动力特性研究

    Institute of Scientific and Technical Information of China (English)

    梅德庆; 何闻; 沈润杰; 陈子辰

    2001-01-01

    In this paper, the dynamic model building of frame foundation for large-scale steam turbine generator set is performed by substructure method. All the major components of frame foundation, including deck, piers, foundation mat, and soil medium, have been included. Deck and piers are treat ed as 3-D beam element, foundation mat is treated as elastic thin plate and simulated by approximate solution of Ritz function. Furthermore, FFAS software package is developed on the basis of the dy namic model, internal characteristics and dynamic response of frame foundation for a 600MW steam turbine-generator set are analysed by FFAS. And some important results are concluded, which is of some value to the design of frame foundation for large-scale steam turbine generator set. Figs 8, ta bles 2 and refs 8.%对大型汽轮发电机组框架式基础利用子结构法进行了动力学建模分析。平台、立柱框架部分采用梁 单元进行离散化,基础底板则采用弹性薄板的Ritz函数近似解来模拟,从而有效地解决了基础与地基的边界 接触问题。根据该动力学模型编制了FFAS框架式基础动力特性分析软件,并对国内某电厂的1台600MW 汽轮发电机组框架式基础进行了动力特性分析计算,并得出了结论。图8表2参8

  10. Generating Large Unit Staffs during Wartime Mobilization

    Science.gov (United States)

    2013-12-10

    Graham Cosmas, An Army for Empire: The United States Army in the Spanish-American War (Columbia, MO: University of Missouri Press, 1971), 195. 76 Ibid...100 Keast, The Procurement and Branch Distribution of Officers, 1. 101 Kent Greenfield, Robert Palmer, and Bell Wiley, The Army Ground Forces...A Gallant Little Army: The Mexico City Campaign, 84-85. 154 Graham Cosmas, An Army for Empire: The United States Army in the Spanish-American War

  11. Large Customers (DR Sellers)

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccot, Sila [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-10-25

    State of the large customers for demand response integration of solar and wind into electric grid; openADR; CAISO; DR as a pseudo generation; commercial and industrial DR strategies; California regulations

  12. Generator Maintenance Scheduling of Large-scale Wind Power Integration Considering Peak Shaving%考虑大规模风电调峰要求的系统机组检修计划

    Institute of Scientific and Technical Information of China (English)

    张宏宇; 印永华; 申洪; 何剑; 赵珊珊

    2012-01-01

    考虑风电运行特性进行发电机组检修安排对优化风电利用和保证系统运行安全意义重大。综合考虑了风电出力运行要求、负荷变化特性与机组调节特性以及机组检修特性,以系统检修成本和风电弃风量为优化目标,以系统发电可靠性和系统调峰充裕性等为约束条件,利用Benders分解法将原始模型分解为主问题(多目标整数规划)和子问题(弃风量计算、系统发电可靠性和调峰充裕性)进行分散协调,对含大规模风电的电力系统机组检修计划进行了研究。最后,利用IEEE—RTS测试系统验证了所述方法的可行性与有效性。%It is important to consider the operational characteristics of wind power in the generator maintenance scheduling for optimizing the use of wind power and ensuring the safety of system operation. A comprehensive model of generator maintenance scheduling, considering the operational characteristics of wind power, the fluctuation characteristics of load and the regulating and maintenance characteristics of units, is established. The model optimization goal is the combination of system maintenance cost and revenue loss of wind energy, which is mainly constrained by the power generation reliability and peak-load regulating adequacy. Based on Benders decomposition, the model is decomposed into two parts: a master problem (deterministic multi-objective integer programming) and three sub-problems (revenue loss of wind energy calculation, power generation reliability and peak-load regulating adequacy) for decentralized coordination, and this method is applied to make maintenance scheduling for all the generators in IEEE-RTS test system with large-scale wind power integration. The results prove that the proposed method is feasible and effective.

  13. Optimal Dispatch of Power System Integrated with Large Scale Photovoltaic Generation Under Carbon Trading Environment%碳交易环境下含大规模光伏电源的电力系统优化调度

    Institute of Scientific and Technical Information of China (English)

    娄素华; 胡斌; 吴耀武; 卢斯煜

    2014-01-01

    Photovoltaic generation does not consume fossil fuels and is free from carbon emission.Developing photovoltaic generation is an effective way of developing a low carbon electricity system.However,with its considerable randomness and intermittence,it brings new uncertainty to power system dispatch.This paper introduces the carbon trading mechanism to power system dispatch based on the concept of low carbon economy.A probability distribution model of solar irradiance and photovoltaic generation output is developed,and scenario reduction technology based on Kantorovich distance is used to reduce the photovoltaic generation output scenarios.On this basis,a model for power system optimal dispatch integrated with large scale photovoltaic generation and considering carbon trading cost is proposed.It has the advantage of balancing the economy, low carbon emission,and reliability of power system operation.A ten-unit test system is simulated via the proposed model to prove its rationality and effectiveness.%光伏发电不消耗化石能源,无碳排放,是电力工业低碳化的有效途径。光伏发电出力具有很大的随机性与间歇性,大容量接入给电力调度带来了新的不确定因素。文中基于低碳经济理念,将碳交易机制引入电力系统经济调度;建立了太阳辐照度和光伏发电出力的概率分布模型,并采用基于 Kantorovich 距离的场景削减技术对光伏发电出力场景进行有效削减;在此基础上构建了考虑大规模光伏电源接入和 CO 2排放经济价值的电力系统优化调度模型,模型兼顾了系统运行的经济性、低碳性和可靠性。利用该模型对10机系统进行了算例仿真,结果验证了所提出模型的合理性和有效性。

  14. 低损耗大有效面积光纤在新一代海缆系统中的应用%Ultra low loss and large effective area fiber for the new generation submarine cable system

    Institute of Scientific and Technical Information of China (English)

    白新宇; 高军诗

    2014-01-01

    This article briefly introduces the technical requirements of optical fiber for N×100 Gbit/s DWDM system and explains the significance of ultra low loss and large effective area fiber in the new generation submarine cable system.%本文结合近年来国际海底光缆系统的发展情况,阐明了N×100 Gbit/s DWDM海缆系统对光纤的技术要求,说明了低损耗、大有效面积光纤在新一代海缆系统的应用及其发展前景。

  15. Study on Life Prediction of Class F Insulation for Stator Coils of Large Turbo-Generators%大型汽轮发电机定子线圈F级绝缘寿命预测方法的研究

    Institute of Scientific and Technical Information of China (English)

    史进渊

    2013-01-01

    Ageing factors and accelerated life-test methods of class F insulation for stator coils of large turbo-generators are presented,while corresponding accelerated test data of both electrical ageing and generalized thermal ageing summarized and analyzed using Weibull distribution model,and simultaneously relevant characteristic parameters of the life calculation formulae determined by reliability and non-linear regression statistics methods.Based on the life expenditure accumulation theory,an introduction is presented to a life prediction method for simultaneous electrical ageing and generalized thermal ageing of class F insulation for stator coils of turbo-generators,and to the life expenditure assignment scheme for class F insulation of water cooled stator coils.The lower life limit of class F insulation for water cooled stator coils affected mainly by electrical ageing is studied under 2 UN and 3 UN conditions.Results show that with above prediction method,the life of class F insulation for stator coils of large turbo-generators can be quantitatively predicted and assessed in the design,manufacture and service stages,thus providing a scientific basis for life determination and extension of relevant insulation in large turbo-generators.%介绍了大型汽轮发电机定子线圈F级绝缘的老化因子与加速寿命试验方法,对电老化与广义热老化的加速寿命试验数据进行了统计分析;用威布尔分布对F级绝缘的电老化和广义热老化的加速寿命试验数据进行了描述;应用可靠性统计和非线性回归方法确定了F级绝缘电老化与广义热老化寿命计算公式的特征参数;依据寿命损耗累积理论,介绍了电老化与广义热老化同时作用的汽轮发电机定子线圈F级绝缘寿命的预测方法和水冷定子线圈F级绝缘寿命损耗的分配方案.采用2倍额定电压2UN和3倍额定电压3 UN的电老化寿命的不同下限值,对以电老化为主要老化因子的水冷定

  16. 大型汽轮发电机风扇静叶改型分析%Analysis on the Remodeled Static Blade Profile of the Large-size Turbine Generator Fan

    Institute of Scientific and Technical Information of China (English)

    张小虎; 胡磊; 干保良; 顾守録; 朱仲贤; 胡晓红

    2013-01-01

    Both static and dynamic blades of the multi-stage axial fan of the large-size turbine generator with axial-radial ventilation were made of the stainless steel. In order to optimize the construction of the generator, the raw material of the static blade would be replaced by the forged aluminum. Affected by rigidity of the aluminum and workmanship of the blade production, distortions took place frequently in the case that blade was manufactured follow-ing up with the original blade proifle. Digital simulation of the aerodynamic performance of the 4-stage fan was done by means of the NUMECA software, through changing two variables, i.e. “increasing the blade thickness and shorten-ing the blade length”. Comparison between the aerodynamic performance of the original blade and that of the remodeled one was carried on. Results showed that the program of“increasing the blade thickness” was better than the origi-nal one. The static press of the 4-stage fan was decreased Both static and dynamic blades of the multi-stage axial fan of the large-size turbine generator with axial-radial ventilation were made of the stainless steel. In order to optimize the construction of the generator, the raw material of the static blade would be replaced by the forged aluminum. Affected by rigidity of the aluminum and workmanship of the blade production, distortions took place frequently in the case that blade was manufactured follow-ing up with the original blade proifle. Digital simulation of the aerodynamic performance of the 4-stage fan was done by means of the NUMECA software, through changing two variables, i.e. “increasing the blade thickness and shorten-ing the blade length”. Comparison between the aerodynamic performance of the original blade and that of the remodeled one was carried on. Results showed that the program of“increasing the blade thickness” was better than the origi-nal one. The static press of the 4-stage fan was decreased only 0.95%against the original

  17. 考虑云层影响的大型光伏发电系统辐照强度计算模型%Solar Irradiance Model for Large-scale Photovoltaic Generation Considering Passing Cloud Shadow Effect

    Institute of Scientific and Technical Information of China (English)

    丁明; 徐志成; 赵波; 毕锐

    2015-01-01

    该文模拟云层遮阴导致大型光伏发电系统辐照强度空间分布不均的情形,在考虑太阳辐射随时间变化的同时重点分析了因云层移动导致的太阳辐射空间分布的随机性和不确定性。首先计算任意地点任意时刻的天文辐射强度,依次考虑大气层衰减、电站所在区域的云层的动态影响,计算到达水平地面的辐照强度,最终得到光伏组件倾斜面上的辐照强度。该模型考虑了地形地貌对日出日落时间的影响、云层分布特性及其和天气的相关性、不同类型的云层透光率、“云隙效应”、云层重叠及云层边缘效应,并能以较高时间分辨率进行仿真计算。由于综合考虑了辐照强度的确定性和随机性部分,该模型对研究光伏发电系统暂稳态分析、实时控制及并网光伏发电对电网的影响具有参考意义。%This paper proposed a model to describe solar irradiance temporal/spatial distribution considering cloud shadows for large-scale photovoltaic (PV) generation. The irradiance time series is calculated focusing on its randomness and uncertainty caused by cloud shadow movement. The irradiance reached the titled PV panel is calculated considering astronomical irradiance, atmospheric attenuation and the impact of transient cloud shadows. This model illustrates the geography impact on the sunrise and sunset time, correlation between cloud and weather type, cloud shadow model considering diversity cloud type transparency , “cloud effect”, cloud overlapping and cloud edge effect. The developed model can be used to analyze PV generation steady and transient performance, real time control and large PV plant integration impact on grid.

  18. 涡流桨搅拌槽内流动非稳定性的大涡模拟%Large Eddy Simulations of Flow Instabilities in a Stirred Tank Generated by a Rushton Turbine

    Institute of Scientific and Technical Information of China (English)

    樊建华; 王运东; 费维扬

    2007-01-01

    The aim of this work is to investigate the flow instabilities in a baffled,stirred tank generated by a single Rushton turbine by means of large eddy simulation (LES).The sliding mesh method was used for the coupling between the rotating and the stationary frame of references.The calculations were carried out on the "Shengcao-21C" supercomputer using a computational fluid dynamics (CFD) code CFX5.The flow fields predicted by the LES simulation and the simulation using standard k-ε model were compared to the results from particle image velocimetry (PIV) measurements.It is shown that the CFD simulations using the LES approach and the standard k-ε model agree well with the PIV measurements.Fluctuations of the radial and axial velocity are predicted at different frequencies by the LES simulation.Velocity fluctuations of high frequencies are seen in the impeller region,while low frequencies velocity fluctuations are observed in the bulk flow.A low frequency velocity fluctuation with a nondimensional frequency of 0.027Hz is predicted by the LES simulation,which agrees with experimental investigations in the literature.Flow circulation patterns predicted by the LES simulation are asymmetric,stochastic and complex,spanning a large portion of the tanks and varying with time,While circulation patterns calculated by the simulation using the standard k-ε model are symmetric.The results of the present work give better understanding to the flow instabilities in the mechanically agitated tank.However,further analysis of the LES calculated velocity Series by means of fast Fourier transform (FFT) and/or spectra analysis are recommended in future work in order to gain more knowledge of the complicated flow phenomena.

  19. Stabilization of a large-capacity and long-distance transmission system by an adjustable speed flywheel generator; Kahensoku FWG ni yoru daiyoryo chokyori soden keito anteika no kento

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, O; Sato, K.; Goto, K.; Sirosaki, T. [Tohoku Electric Power Co. Inc, Miyagi (Japan); Sanekata, J.; Amano, M.; Endo, M. [Hitachi Ltd., Tokyo (Japan)

    1997-06-20

    An adjustable speed flywheel generator (FWG) is composed of a dynamotor and a flywheel which can accumulate energy as rotational energy. Its adjustable device operates owing to exciting the rotors by three-phase current. When the rotational speed does not coincide with the synchronous one, difference between the two, namely the slipped frequency, excites the rotors. According to this principle, the flywheel can run synchronizing with the transmission system. Selection of the location for FWGs being important from the standpoint of large-capacity and long-distance transmission, a PQ-sensitivity method has been proposed as a new technique, which can estimate the effect of both FWG`s active and reactive power with ease. Besides, regarding an input signal for stabilizing control, new method has been developed which apply the frequency of the bus instead of the power flow. Owing to this method, conventional stepwise changes of the power flow at every opening three-phase single-circuit have disappeared. As for the capacity of the FWG, the fact that the capacity of the exciter depends on the slip investigated, a designing method has been proposed. 8 refs., 17 figs., 3 tabs.

  20. Large - current V - I measurement of second generation HTS tapes with eliminating the effects of Joule heat%第二代高温超导带材的大电流V-I测量与热效应消除

    Institute of Scientific and Technical Information of China (English)

    单雪娇; 白心悟; 朱娇; 桑丽娜; 蔡传兵; 朱红妹; 张义邴

    2012-01-01

    A large - current V -1 measurement system with a current range of 0 - 400 A and under zero applied field for second generation high temperature superconducting (HTS) tapes was reported in this paper. HTS tape samples and current carrying electropoles were immersed in liquid nitrogen. Current - voltage scanning, experimental data collecting and data processing were performed automatically by computer based on digital communication interface. By analyzing the electric and heat transportation of HTS tapes, the current electropoles and connections to HTS tape samples were optimized. The influence of the linearly climbing of V -1 curve and Joule heat effect was weakened. The ability of high current scanning, accuracy and stability of the measurement system were enhanced.%介绍了0~400A零外场下高温超导带材大电流V-I测试系统.实验利用计算机自动实现电流/电压扫描、采集并处理数据,测量温度为液氮温区.利用导热分析,优化仪器设计,最大程度地消除V-I测量的爬坡效应和大电流的热效应,提高试样的耐大电流冲击能力、测量精度和稳定性.

  1. Failure Analysis on Boost Gear of A Large Capacity Wind Power Generator%大功率风力发电机增速齿轮断裂原因分析

    Institute of Scientific and Technical Information of China (English)

    马小明; 伍聂修

    2011-01-01

    By means of macro and micro fracture morphology observation, chemical composition analysis, microstructure observation and hardness test, the failure causes of the boost gear of a large capacity wind power generator were investigated systemically. The results show that densely distributed pits and micro-voids existed on the external surface of the gear. which were the crack origins, Caused the mirco cracks propagation under the combined action of severe impact and bending load, and finally resulted in the fatigue fracture.%通过断口宏微观形貌观察、化学成分分析、显微组织观察以及硬度测试等方法,系统分析了某大功率风力发电机增速齿轮断裂的原因。结果表明:轮齿外表面存在密集分布的点蚀坑及微孔缺陷,是裂纹源;在较高水平的冲击与弯曲载荷共同作用下使微裂纹扩展,从而最终导致齿轮疲劳断裂。

  2. Generating Units

    Data.gov (United States)

    Department of Homeland Security — Generating Units are any combination of physically connected generators, reactors, boilers, combustion turbines, and other prime movers operated together to produce...

  3. Methodology for Automatic Generation of Models for Large Urban Spaces Based on GIS Data/Metodología para la generación automática de modelos de grandes espacios urbanos desde información SIG/

    Directory of Open Access Journals (Sweden)

    Sergio Arturo Ordóñez Medina

    2012-12-01

    Full Text Available In the planning and evaluation stages of infrastructure projects, it is necessary to manage huge quantities of information. Cities are very complex systems, which need to be modeled when an intervention is required. Suchmodels allow us to measure the impact of infrastructure changes, simulating hypothetic scenarios and evaluating results. This paper describes a methodology for the automatic generation of urban space models from GIS sources. A Voronoi diagram is used to partition large urban regions and subsequently define zones of interest. Finally, some examples of application models are presented, one used for microsimulation of traffic and another for air pollution simulation.En las etapas de planeación y evaluación de proyectos de infraestructura es necesario manejar grandes cantidades de información. Las ciudades son sistemas complejos que deben ser modeladas para ser intervenidas. Estos modelos permitirón medir el impacto de los cambios de infraestructura, simular escenarios hipotéticos y evaluar resultados. Este artículo describe una metodología para generar automáticamente modelos espaciales urbanos desde fuentes SIG: Un diagrama de Voronoi es usado para dividir grandes regiones urbanas, y a continuación serán definidas las zonas de interés. Finalmente, algunos ejemplos de modelos de aplicación serán presentados, uno usado para microsimulación de tráfico y el otro para simular contaminación atmosférica.

  4. Large deviations

    CERN Document Server

    Varadhan, S R S

    2016-01-01

    The theory of large deviations deals with rates at which probabilities of certain events decay as a natural parameter in the problem varies. This book, which is based on a graduate course on large deviations at the Courant Institute, focuses on three concrete sets of examples: (i) diffusions with small noise and the exit problem, (ii) large time behavior of Markov processes and their connection to the Feynman-Kac formula and the related large deviation behavior of the number of distinct sites visited by a random walk, and (iii) interacting particle systems, their scaling limits, and large deviations from their expected limits. For the most part the examples are worked out in detail, and in the process the subject of large deviations is developed. The book will give the reader a flavor of how large deviation theory can help in problems that are not posed directly in terms of large deviations. The reader is assumed to have some familiarity with probability, Markov processes, and interacting particle systems.

  5. Generational diversity.

    Science.gov (United States)

    Kramer, Linda W

    2010-01-01

    Generational diversity has proven challenges for nurse leaders, and generational values may influence ideas about work and career planning. This article discusses generational gaps, influencing factors and support, and the various generational groups present in today's workplace as well as the consequences of need addressing these issues. The article ends with a discussion of possible solutions.

  6. Large deviations

    CERN Document Server

    Hollander, Frank den

    2008-01-01

    This book is an introduction to the theory and applications of large deviations, a branch of probability theory that describes the probability of rare events in terms of variational problems. By focusing the theory, in Part A of the book, on random sequences, the author succeeds in conveying the main ideas behind large deviations without a need for technicalities, thus providing a concise and accessible entry to this challenging and captivating subject. The selection of modern applications, described in Part B of the book, offers a good sample of what large deviation theory is able to achieve

  7. Molten salt reactors and the oil sands: odd couple or key to north american energy independence?

    Energy Technology Data Exchange (ETDEWEB)

    LeBlanc, D., E-mail: d_leblanc@rogers.com [Ottawa Valley Research Associates Ltd., Ottawa, Ontario (Canada); Quesada, M.; Popoff, C.; Way, D. [Penumbra Energy, Calgary, Alberta (Canada)

    2012-07-01

    The use of nuclear power to aid oil sands development has often been proposed largely due to the virtual elimination of natural gas use and thus a large reduction in GHG emissions. Nuclear power can replace natural gas for process steam production (SAGD) and electricity generation but also potentially for hydrogen production to upgrade bitumen for pipeline transit, synthetic crude production and even at the final refinery stage. Prior candidates included CANDU and gas cooled Pebble Bed Reactors. The case for CANDU use can be shown to be marginally economic with a proven technology but with an uncertainty of current construction costs and too large a unit size (~2400 MWth). PBRs offered modest theoretical cost savings, smaller unit size and the ability to offer higher temperatures needed for thermochemical hydrogen production from water. Interest in PBRs however has greatly waned with the cancellation of their major South African development program which highlighted the severe challenges of helium as a coolant and TRISO fuel manufacturing. More recently, Small Modular Reactors based on scaled down light water reactor technology have attracted interest but are unlikely to compete economically outside of niche applications. However, a 'new' reactor option, the Molten Salt Reactor, has been rapidly gaining momentum over the past decade. This 'new' technology was actually developed over 50 years ago as a thorium breeder reactor to compete with the sodium cooled fast breeder reactor (U-Pu cycle). During this time two molten salt test reactors were constructed. A modern version however would likely be a simpler converter design using Low Enriched Uranium but needing only a small fraction the uranium resources of LWRs or CANDUs. Besides resource sustainability, these unique designs offer large potential improvements in the areas of capital costs, safety and nuclear waste. This presentation will explain the unique attributes and advantages of these

  8. Instant Generation

    Science.gov (United States)

    Loveland, Elaina

    2017-01-01

    Generation Z students (born between 1995-2010) have replaced millennials on college campuses. Generation Z students are entrepreneurial, desire practical skills with their education, and are concerned about the cost of college. This article presents what need to be known about this new generation of students.

  9. 中国大都市新移民的住房模式与影响机制%Housing Conditions, Patterns and Mechanisms of Second Generation Migrants in Urban China:A Case Study of Six Large Cities

    Institute of Scientific and Technical Information of China (English)

    李志刚

    2012-01-01

    With a database based on 3168 copies of questionnaires collected from six Chinese cities of Guangzhou, Dongguan, Shenyang, Chengdu, Hangzhou and Zhengzhou, this study examines housing conditions, patterns and determinants of second-generation migrants of urban China. With a series of quantitative analysis, it is found that three types of Chinese new migrants, labor migrants, intellectual migrants, and investor migrants have different housing conditions. For instance, the average housing area of new migrants is about 20.69 sq. M., while that of the intellectual migrants is the biggest (24.87 sq. M.) and that of the labor migrants is the smallest (16.26 sq. M.). In terms of the quality of housing facilities, the score of the facility index for the new migrants in general is by no means high, about 0.35. Moreover, investor migrants hold the best facilities, while labor migrants hold the worst, and intellectual migrants is in between. It is indicated that housing conditions of new migrants are largely differentiated. Second, after three decades of market reform, housing conditions and patterns of new migrants are still mainly determined by institutional factors such as hukou. In addition, housing facility qualities are mainly influenced by such factors as hukou status, income, educational background, marriage, age and migrant types, and hukou is the major determinant for the housing facility quality of second generation migrants.%利用在广州、东莞、沈阳、成都、杭州、郑州6市进行配额抽样调查(2008-2009年)所获得的3168份问卷,采用Logistic回归分析等计量方法,研究快速城市化下中国大都市“新移民”的住房状况、模式与机制.研究表明,城市新移民已经成为一个日趋分化的复合群体,可分为劳力型移民、智力型移民、投资型移民三类,三类新移民住房状况存在较大差异.总体上,新移民人均住房面积为20.69m2,其中智力型新移民的人均住房面积最高(24

  10. Rainfall generation

    Science.gov (United States)

    Sharma, Ashish; Mehrotra, Raj

    This chapter presents an overview of methods for stochastic generation of rainfall at annual to subdaily time scales, at single- to multiple-point locations, and in a changing climatic regime. Stochastic rainfall generators are used to provide inputs for risk assessment of natural or engineering systems that can undergo failure under sustained (high or low) extremes. As a result, generation of rainfall has evolved to provide options that adequately represent such conditions, leading to sequences that exhibit low-frequency variability of a nature similar to the observed rainfall. The chapter consists of three key sections: the first two outlining approaches for rainfall generation using endogenous predictor variables and the third highlighting approaches for generation using exogenous predictors often simulated to represent future climatic conditions. The first section presents approaches for generation of annual and seasonal rainfall and daily rainfall, both at single-point locations and multiple sites, with an emphasis on alternatives that ensure appropriate representation of low-frequency variability in the generated rainfall sequences. The second section highlights advancements in the subdaily rainfall generation procedures including commonly used approaches for daily to subdaily rainfall generation. The final section (generation using exogenous predictors) presents a range of alternatives for stochastic downscaling of rainfall for climate change impact assessments of natural and engineering systems. We conclude the chapter by outlining some of the key challenges that remain to be addressed, especially in generation under climate change conditions, with an emphasis on the importance of incorporating uncertainty present in both measurements and models, in the rainfall sequences that are generated.

  11. Optimal Operation of Pumped Hydro Energy Storage in Power System With Large Integration of Photovoltaic Generation%应对光伏并网的抽水蓄能电站优化运行

    Institute of Scientific and Technical Information of China (English)

    王辉; 崔建勇

    2014-01-01

    随着太阳能光伏的快速发展,光伏发电随机性与间歇性特点对电力系统的安全稳定运行带来了诸多挑战。建立供电可靠性评估模型评价光伏并网对电力系统运行的影响。提出采用抽水蓄能电站配合光伏发电运行来提高系统的可靠性。以成本最小化为目标建立抽水蓄能电站优化调度模型,采用蒙特卡罗模拟需求负载的不确定性,光伏出力的不确定性以及传统机组故障。运用遗传算法配合禁忌搜索对模型求解。通过IEEE-24节点算例分析验证模型与算法的可行性。仿真结果表明提出的方法在电力系统运行具有可靠性。而且,采取抽水蓄能电站运行修正模式可以有效解决电力过剩问题。%With the rapid development of photovoltaic (PV) generation the randomness and intermittence of PV generation evidently affect the secure and stable operation of power grid. A power supply reliability evaluation model is established to assess the impacts on grid-connected PV generation on power grid operation. It is proposed to improve power system reliability by pumped storage power station coordinated with grid-connected PV generation. Taking the minimized cost as the object, an optimal dispatching model of pumped storage power station is built, and the uncertainty of load demand, the uncertainty of PV generation output and the faults of traditional generating units are simulated by Monte Carlo simulation. The proposed dispatching model is solved by genetic algorithm combined with Tabu search. The feasibility of the proposed model and algorithm is validated by IEEE 24-bus system, and simulation results show that using the proposed method the reliability of power grid can be improved and the electric power surplus can be effectively coped with.

  12. Report Generator

    OpenAIRE

    2016-01-01

    Download data from HP Quality Center using of OTA Client. Implementation must be scalable to all projects under test. That is, it will be possible to generate automatically test reports at least for 2010, Modulaser and Gen2 (FW or SW). Report Generator is a software implemented in VBA that allows get data from HP Quality Center for export it (either tables, charts or text) to a document in Word format. Report Generator es un Software implementado en VBA que permite extraer datos de HP Q...

  13. 大型并网光伏发电系统方案设计探讨%Discussion on the Design of Large-scale Grid-connected Photovoltaic Power Generation System

    Institute of Scientific and Technical Information of China (English)

    马春兰

    2015-01-01

    As a non-exhausted and clean energy source, the solar energy attracts worldwide attention nowadays.A grid-connected photovoltaic power generation project located in the Ruoqiang Industry Park is presented, including the design of photovoltaic power generation system and the optimization scheme, which could be a useful reference for similar pro-jects.%太阳能作为一种永不枯竭、无污染的清洁能源,已经越来越受到科技工作者们的重视,各国也在努力开发和利用太阳能。以若羌产业园区光伏并网项目为依托,介绍了光伏发电站的发电系统方案设计及其优化设计,可供类似工程参考。

  14. Porous La0.6Sr0.4CoO3-δ thin film cathodes for large area micro solid oxide fuel cell power generators

    DEFF Research Database (Denmark)

    Garbayo, A.; Esposito, Vincenzo; Sanna, Simone

    2014-01-01

    Porous La0.6Sr0.4CoO3-δ thin films were fabricated by pulsed laser deposition for being used as a cathode for micro solid oxide fuel cell applications as MEMS power generators. Symmetrical La0.6Sr0.4CoO3-δ/ yttria-stabilized zirconia/La0.6Sr0.4CoO3-δ free-standing membranes were fabricated using ...

  15. Querying Large Biological Network Datasets

    Science.gov (United States)

    Gulsoy, Gunhan

    2013-01-01

    New experimental methods has resulted in increasing amount of genetic interaction data to be generated every day. Biological networks are used to store genetic interaction data gathered. Increasing amount of data available requires fast large scale analysis methods. Therefore, we address the problem of querying large biological network datasets.…

  16. Generation of Well-Relaxed All-Atom Models of Large Molecular Weight Polymer Melts: A Hybrid Particle-Continuum Approach Based on Particle-Field Molecular Dynamics Simulations.

    Science.gov (United States)

    De Nicola, Antonio; Kawakatsu, Toshihiro; Milano, Giuseppe

    2014-12-09

    A procedure based on Molecular Dynamics (MD) simulations employing soft potentials derived from self-consistent field (SCF) theory (named MD-SCF) able to generate well-relaxed all-atom structures of polymer melts is proposed. All-atom structures having structural correlations indistinguishable from ones obtained by long MD relaxations have been obtained for poly(methyl methacrylate) (PMMA) and poly(ethylene oxide) (PEO) melts. The proposed procedure leads to computational costs mainly related on system size rather than to the chain length. Several advantages of the proposed procedure over current coarse-graining/reverse mapping strategies are apparent. No parametrization is needed to generate relaxed structures of different polymers at different scales or resolutions. There is no need for special algorithms or back-mapping schemes to change the resolution of the models. This characteristic makes the procedure general and its extension to other polymer architectures straightforward. A similar procedure can be easily extended to the generation of all-atom structures of block copolymer melts and polymer nanocomposites.

  17. Photonic Generation of Phase-Coded Microwave Signal with Large Frequency Tunability%光生频率大范围可调的相位编码微波信号

    Institute of Scientific and Technical Information of China (English)

    刘双; 钱祖平; 王荣; 蒲涛

    2013-01-01

    提出并验证了一种光生相位编码微波信号的方法,其主要原理是对编码的相干光边带进行差拍,从而得到高频率、高编码数率、低噪声的相位编码微波信号.该方法简单易行,利于集成,能适应不同的编码速率,产生的微波信号频率大范围可调,能解决电子电路方法中遇到的“电子瓶颈”问题.介绍了所提方法的原理,并进行了理论推导,在系统分析中加入了对调制器驱动信号相位噪声的分析,使得系统建模更加科学完善;实验设计制作了所需的光纤光栅带阻滤波器,产生了20 GHz和25 GHz的相位编码微波信号,实验结果与理论值几乎吻合,证明了所提方法提高脉冲压缩比的能力.%A photonic approach to generating a phase-coded microwave signal is proposed and demonstrated. The main principle is to beat the encoded coherent optical sideband to obtain high-frequency, high-coding rate, low-noise encoded microwave signals. The proposed technique, which is simple and conducive to integration, can adapt to different coding rates, generate phase-coded microwave signals with tunable frequency, and solve the bottleneck problem of traditional electronic approaches. The principle is discussed in detail. Mathematical models are developed to consider perturbation on the generated coded signal caused by the phase fluctuations of the microwave driving signal and the optical carrier. The required fiber Bragg grating notch filter is fabricated, and 20 GHz and 25 GHz phase-coded microwave signals are experimentally generated, respectively. The experimental results agree well with theoretical values, and it is proved that the proposed method improves the pulse compression capability.

  18. Reducing air pollution from electricity-generating large combustion plants in the European Union. An assessment of potential emission reductions of NO{sub X}, SO{sub 2} and dust

    Energy Technology Data Exchange (ETDEWEB)

    Lodewijks, P.; Pieper, H.; Van Wortswinkel, L. [ETC partner Flemish Institute for Technological Research (VITO) (Belgium); Boyce, B.; Adams, M.; Goossens, E. [EEA, Copenhagen (Denmark)

    2013-06-15

    An assessment of potential emission reductions of NO{sub X}, SO{sub 2} and dust - This report presents an assessment of the hypothetical emission reduction potential of NO{sub x}, SO{sub 2} and dust from more than 1 500 of Europe's large combustion plants that operated in 2009. Emissions of these air pollutants could be significantly lower if all plants were to meet the emission limit values as set out in European Union legislation. (Author)

  19. A CERN-based high-intensity high-energy proton source for long baseline neutrino oscillation experiments with next-generation large underground detectors for proton decay searches and neutrino physics and astrophysics

    CERN Document Server

    Rubbia, A

    2010-01-01

    The feasibility of a European next-generation very massive neutrino observatory in seven potential candidate sites located at distances from CERN ranging from 130 km to 2300 km, is being considered within the LAGUNA design study. The study is providing a coordinated technical design and assessment of the underground research infrastructure in the various sites, and its coherent cost estimation. It aims at a prioritization of the sites within summer 2010 and a start of operation around 2020. In addition to a rich non-accelerator based physics programme including the GUT-scale with proton decay searches, the detection of a next-generation neutrino superbeam tuned to measure the flavor-conversion oscillatory pattern (i.e. 1st and 2nd oscillation maxima) would allow to complete our understanding of the leptonic mixing matrix, in particular by determining the neutrino mass hierarchy and by studying CP-violation in the leptonic sector, thereby addressing the outstanding puzzle of the origin of the excess of matter ...

  20. Microwave generator

    Science.gov (United States)

    Kwan, T.J.T.; Snell, C.M.

    1987-03-31

    A microwave generator is provided for generating microwaves substantially from virtual cathode oscillation. Electrons are emitted from a cathode and accelerated to an anode which is spaced apart from the cathode. The anode has an annular slit there through effective to form the virtual cathode. The anode is at least one range thickness relative to electrons reflecting from the virtual cathode. A magnet is provided to produce an optimum magnetic field having the field strength effective to form an annular beam from the emitted electrons in substantial alignment with the annular anode slit. The magnetic field, however, does permit the reflected electrons to axially diverge from the annular beam. The reflected electrons are absorbed by the anode in returning to the real cathode, such that substantially no reflexing electrons occur. The resulting microwaves are produced with a single dominant mode and are substantially monochromatic relative to conventional virtual cathode microwave generators. 6 figs.

  1. Solar Generator

    Science.gov (United States)

    1985-01-01

    The Vanguard I dish-Stirling module program, initiated in 1982, produced the Vanguard I module, a commercial prototype erected by the Advanco Corporation. The module, which automatically tracks the sun, combines JPL mirrored concentrator technology, an advanced Stirling Solar II engine/generator, a low cost microprocessor-controlled parabolic dish. Vanguard I has a 28% sunlight to electricity conversion efficiency. If tests continue to prove the system effective, Advanco will construct a generating plant to sell electricity to local utilities. An agreement has also been signed with McDonnell Douglas to manufacture a similar module.

  2. Comparison and Analysis of Abnormal Cooling Water Outlet Temperature of Large Generator%大型发电机运行中线棒出水温度异常对比分析

    Institute of Scientific and Technical Information of China (English)

    韩金华; 张晓鹏; 贾少华; 付瑞清

    2016-01-01

    In this paper, the different conditions of the abnormal temperature of the cooling water of stator line bar in the operation of three 600MW generators are introduced. The longitudinal contrast and the latitudinal contrast analysis method are adopted. And the guidance on the considerations, data characteristics and analysis methods are provided.%本文介绍了三台600MW 大型发电机运行中定子线棒出水温度异常的不同情况,采用横向对比和纵向对比的分析方法,对分析中应考虑的注意事项、数据特征、分析方法等提出了指导意见。

  3. Study on reinforcement pattern of foundation for large sized wind turbine-generator set%大型风力发电机组基础结构配筋型式研究

    Institute of Scientific and Technical Information of China (English)

    许新勇; 齐志诚; 刘宪亮

    2012-01-01

    A 3-D finite element model of the structure of the extended foundation for wind turbine-generator set is established, and then various foundation reinforcement patterns are analyzed in accordance with the complexity of wind load. Furthermore, the impacts from the patterns of the bi-directional orthogonal reinforcement, the diametral circular fabric reinforcement, etc. on the status of structure stress and displacement are studied by introducing the contact properties and the concrete material nonlinearity into the study along with the analysis on the degrees of the impacts from various loading effects; from which the law of the foundation stress and displacement is defined. The calculation result not only gives a reasonably designed and economic method for the arrangement of reinforcement for the foundation of wind turbine-generator set, but also provides a scientific basis for the design and optimization of the foundation.%建立了风机扩展式基础结构的三维有限元数值模型,结合风荷载的复杂性,对基础结构各种配筋方式进行计算分析.引入接触设置和混凝土材料非线性,研究了双向正交与径环向配筋等方式对结构受力和变位的影响,分析了不同荷载作用方式的影响程度,明确了基础结构受力和变位规律.计算结果提出了风机基础设计合理的、经济的配筋方法,为基础的设计和优化提供了科学依据.

  4. Large Superconducting Magnet Systems

    CERN Document Server

    Védrine, P.

    2014-07-17

    The increase of energy in accelerators over the past decades has led to the design of superconducting magnets for both accelerators and the associated detectors. The use of Nb−Ti superconducting materials allows an increase in the dipole field by up to 10 T compared with the maximum field of 2 T in a conventional magnet. The field bending of the particles in the detectors and generated by the magnets can also be increased. New materials, such as Nb3Sn and high temperature superconductor (HTS) conductors, can open the way to higher fields, in the range 13–20 T. The latest generations of fusion machines producing hot plasma also use large superconducting magnet systems.

  5. Na2ZnGe2S6: A New Infrared Nonlinear Optical Material with Good Balance between Large Second-Harmonic Generation Response and High Laser Damage Threshold.

    Science.gov (United States)

    Li, Guangmao; Wu, Kui; Liu, Qiong; Yang, Zhihua; Pan, Shilie

    2016-06-15

    The development of frequency-conversion technology in the infrared region is in urgent need of new excellent infrared nonlinear optical (IR NLO) materials. How to achieve a good balance between laser damage threshold (LDT) and NLO coefficient (dij) for new IR NLO candidates is still a challenge. The combination of the highly electropositive alkali metal (Na) and Zn with d(10) electronic configuration into crystal structure affords one new IR NLO material, Na2ZnGe2S6. It exhibits excellent properties including a wide transparent region (0.38-22 μm), large band gap (3.25 eV), and especially a balance between a strong NLO coefficient (30-fold that of KDP) and a high LDT (6-fold that of AgGaS2), indicating a promising application in the IR region. Moreover, novel common-vertex-linked wavelike ∞[GeS3]n chains are interestingly discovered in Na2ZnGe2S6, which rarely exist in the reported thiogermanides containing alkali metals. In addition, calculated SHG density and dipole moment demonstrate that the large NLO response is mainly attributed to the cooperative effects of the [GeS4] and [ZnS4] units.

  6. Martian Generation

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Independent, Internet savvy and with their own Martian language, China’s post-90s generation is rewriting the rules of behavior september 14 was the 18th birth-day of Zhang Zhaoyu from Sichuan Province. He is a new student at Peking University,

  7. Generative Contexts

    Science.gov (United States)

    Lyles, Dan Allen

    Educational research has identified how science, technology, engineering, and mathematics (STEM) practice and education have underperforming metrics in racial and gender diversity, despite decades of intervention. These disparities are part of the construction of a culture of science that is alienating to these populations. Recent studies in a social science framework described as "Generative Justice" have suggested that the context of social and scientific practice might be modified to bring about more just and equitable relations among the disenfranchised by circulating the value they and their non-human allies create back to them in unalienated forms. What is not known are the underlying principles of social and material space that makes a system more or less generative. I employ an autoethnographic method at four sites: a high school science class; a farm committed to "Black and Brown liberation"; a summer program geared towards youth environmental mapping; and a summer workshop for Harlem middle school students. My findings suggest that by identifying instances where material affinity, participatory voice, and creative solidarity are mutually reinforcing, it is possible to create educational contexts that generate unalienated value, and circulate it back to the producers themselves. This cycle of generation may help explain how to create systems of justice that strengthen and grow themselves through successive iterations. The problem of lack of diversity in STEM may be addressed not merely by recruiting the best and the brightest from underrepresented populations, but by changing the context of STEM education to provide tools for its own systematic restructuring.

  8. Synchronous generators

    CERN Document Server

    Boldea, Ion

    2005-01-01

    This work begins with an introduction to energy resources and the main electric energy conversion solutions, along with efficiency and environmental merits and demerits. The classification and principles of various electric generator topologies are covered alongside their power ratings and main applications including constant-speed synchronous gene

  9. Radiatively Generated $\

    CERN Document Server

    Joshipura, A S; Joshipura, Anjan S.; Rindani, Saurabh D.

    2003-01-01

    We study the consequences of assuming that the mass scale $\\Delta_{odot}$ corresponding to the solar neutrino oscillations and mixing angle $U_{e3}$ corresponding to the electron neutrino oscillation at CHOOZ are radiatively generated through the standard electroweak gauge interactions. All the leptonic mass matrices having zero $\\Delta_{odot}$ and $U_{e3}$ at a high scale lead to a unique low energy value for the $\\Delta_{odot}$ which is determined by the (known) size of the radiative corrections, solar and the atmospheric mixing angle and the Majorana mass of the neutrino observed in neutrinoless double beta decay. This prediction leads to the following consequences: ($i$) The MSSM radiative corrections generate only the dark side of the solar neutrino solutions. ($ii$) The inverted mass hierarchy ($m,-m,0$) at the high scale fails in generating the LMA solution but it can lead to the LOW or vacuum solutions. ($iii$) The $\\Delta_{odot}$ generated in models with maximal solar mixing at a high scale is zero t...

  10. Global control of large-scale wind turbine generator based on hybrid automata%基于混杂自动机的大型风力发电机组全程控制

    Institute of Scientific and Technical Information of China (English)

    高峰

    2012-01-01

    风力发电系统是具有不确定性的复杂非线性系统,机组运行 工况变化十分频繁.通过对风力发电机组的系统特性分析,发现风力发电系统呈现出混杂系统的典型特征.因此,基于混杂自动机理论建立了1.5 MW双馈型风电机组的混杂动态模型,并根据风力发电机组控制策略设计了能够在机组运行中实现全程自动化的混杂控制系统.仿真结果表明,基于混杂自动机的动态模型可以实现风电机组的全程模拟,所设计的混杂控制系统能够满足风电机组全程控制要求,证明了混杂系统理论应用于风力发电研究领域的有效性.%Wind turbine generator (WTG) system is a complex nonlinear system involving some uncertain disturbances, and its working states change multifarious. A fact was discovered that wind turbine generator showed the typical feature of hybrid system by analyzing its characteristics. Therefore, the hybrid dynamic model of 1.5 MW Doubly-fed WTG was built based on theory of hybrid automata, at same time hybrid control system was designed for solving the problem of the global automation according to the WTG control strategy. Emulation results present the hybrid automata model can accomplish the global simulation of WTG, and the designed hybrid control system fulfills the demand of WTG global control. Moreover, the validity and practicability of applying hybrid system theory in the field of wind power are demonstrated.

  11. ABi2 (IO3 )2 F5 (A=K, Rb, and Cs): A Combination of Halide and Oxide Anionic Units To Create a Large Second-Harmonic Generation Response with a Wide Bandgap.

    Science.gov (United States)

    Liu, Hongming; Wu, Qi; Jiang, Xingxing; Lin, Zheshuai; Meng, Xianggao; Chen, Xingguo; Qin, Jingui

    2017-08-01

    A family of nonlinear optical materials that contain the halide, oxide, and oxyhalide polar units simultaneously in a single structure, namely ABi2 (IO3 )2 F5 (A=K (1), Rb (2), and Cs (3)), have been designed and synthesized. They crystallize in the same polar space group (P21 ) with a two-dimensional double-layered framework constructed by [BiF5 ](2-) and [BiO2 F4 ](5-) units connected to each other by four F atoms, in which two [IO3 ](-) groups are linked to [BiO2 F4 ](5-) unit on the same side. A hanging Bi-F bond of [BiF5 ](2-) unit is located on the other side via ionic interaction with the layer-inserted alkali metal ions to form three-dimensional structure. The well-ordered alignments of these polar units lead to a very strong second-harmonic generation response of 12 (1), 9.5 (2), and 7.5 (3) times larger than that of potassium dihydrogen phosphate under 1064 nm laser radiation. All of them exhibited a wide energy bandgap over 3.75 eV, suggesting that they will have a high laser damage threshold. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. 大型风力发电机转轴加工工艺难点解析%Analysis on the Technological Difficulties in Machining the Shaft of the Large-size Wind Turbine Generator

    Institute of Scientific and Technical Information of China (English)

    王艳芳; 丁立国

    2014-01-01

    With the development tendency of greater power and higher reliability of the wind turbine generator, the construction of it was improved continuously. The configuration that the rotor outlet from axle hole connecting to the slip ring was becoming more and more popular. The improved technology brought up with such technological difficulties in machining the shaft as the outlet inclined hole and deep hole on the shaft. Through analyzing the drilling and cutting process on the shaft, the technological procedure was optimized and fixtures & tools were innovated, thus, to solve the technological difficulties in machining the shaft.%随着风力发电机大功率、高可靠性的发展趋势,电机的结构不断改进,转子引出线从轴孔穿出与滑环相连的结构越来越普遍。结构的改进给转轴制造工艺带来了难题,比如转轴出线斜孔加工、轴向深孔加工。通过对转轴钻削加工过程的分析,对工艺流程进行优化,对加工用工装和刀具作了改进,解决了大型风力发电机转轴加工难题。

  13. Development of large scale wind energy conservation system. Development of control techniques for assembly-type wind power generating systems; Ogata furyoku hatsuden system no kaihatsu. Shugogata furyoku hatsuden system no seigyo gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Takita, M. [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for development of control techniques for assembly-type wind power generating systems. The study on optimum system configuration produces 50 to 100kW wind power units for screening small-size wind power plant types, and, at the same time, surveys performance of commercial units and experiences of 9 makers capable of producing the above units. As a result, 3 MICON`s units (output: 100kW, active YAW control, monopole tower, maximum wind speed: 60m/s) are selected. The study on optimum operational techniques integrates 2 medium-size power units into a power line, showing a service factor of 30.2% on the annual average, monthly varying in a range from 11.8 to 45.0%. These units, installed in Miyako Island, were attacked by 3 typhoons of wind velocity of 25m/s or higher in 1994, and the only damage recorded is that of the anemoscope/anemometer. It is found that No.1 unit is located at a better geographical point than the No.2 unit, to produce a higher output. 3 figs., 3 tabs.

  14. Idea generation

    DEFF Research Database (Denmark)

    Tollestrup, Christian H. T.; Laursen, Linda Nhu

    2015-01-01

    of an idea generation whether the outset is ill defined and questioned as opposed to straightforward ideation on a proposal for a solution? The hypothesis is that an approach to ideation where ambiguity and discrepancy deliberately is sought creates more radical innovation that an approach without this...... as having new sociocultural meaning in line with Vergantis definition of radical innovation. This paper discusses the results of an experiment with 32 students on idea generation and product concept development. The experiment was setup as and A-B comparison between two set of students with the same...... different solutions when seeking ambiguity and discrepancy. Within the very limited experiment the conclusion seems to be very clear, it leads to more innovation if the designer seeks to question the framing and scope of the task. So seeking ambiguity and discrepancy in the ideation phase aligns...

  15. Photon generator

    Science.gov (United States)

    Srinivasan-Rao, Triveni

    2002-01-01

    A photon generator includes an electron gun for emitting an electron beam, a laser for emitting a laser beam, and an interaction ring wherein the laser beam repetitively collides with the electron beam for emitting a high energy photon beam therefrom in the exemplary form of x-rays. The interaction ring is a closed loop, sized and configured for circulating the electron beam with a period substantially equal to the period of the laser beam pulses for effecting repetitive collisions.

  16. Heliostat Tracking System Design for Large-array Type Solar Thermal Power Generation%大型阵列式太阳能热发电定日镜跟踪系统设计

    Institute of Scientific and Technical Information of China (English)

    田行; 刘立群; 葛竹; 曹伟; 张国梁

    2016-01-01

    In order to effectively improve the efficiency of the solar tower power generation system,the two-axis he-liostat tracking device is designed by using visual Sun trajectory tracking combined with photoelectric tracking scheme. The sun time angle,declination angle,solar altitude angle and azimuth angle,are introduced to deduce the altitude angle and azimuth angle of heliostats,and a two-axis tracking control system is designed,which is based on the solar position algorithm. The analysis and research results show that the device can accurately tracking the sun and can effectively improve the utilization rate of solar energy.%为了有效提高太阳能塔式发电系统的发电效率,采用视日运行轨迹跟踪和光电跟踪相结合的方案,设计了双轴定日镜跟踪装置。首先介绍了时角和赤纬角以及太阳高度角和方位角的计算公式,进而推导出了定日镜的高位角和方位角计算方程,并以此为依据设计了一种基于太阳位置算法的双轴跟踪控制系统。理论分析与实验结果表明,该装置能够准确跟踪太阳,并且能有效提高太阳能的利用率。

  17. Generation and analysis of a large-scale expressed sequence Tag database from a full-length enriched cDNA library of developing leaves of Gossypium hirsutum L.

    Directory of Open Access Journals (Sweden)

    Min Lin

    Full Text Available BACKGROUND: Cotton (Gossypium hirsutum L. is one of the world's most economically-important crops. However, its entire genome has not been sequenced, and limited resources are available in GenBank for understanding the molecular mechanisms underlying leaf development and senescence. METHODOLOGY/PRINCIPAL FINDINGS: In this study, 9,874 high-quality ESTs were generated from a normalized, full-length cDNA library derived from pooled RNA isolated from throughout leaf development during the plant blooming stage. After clustering and assembly of these ESTs, 5,191 unique sequences, representative 1,652 contigs and 3,539 singletons, were obtained. The average unique sequence length was 682 bp. Annotation of these unique sequences revealed that 84.4% showed significant homology to sequences in the NCBI non-redundant protein database, and 57.3% had significant hits to known proteins in the Swiss-Prot database. Comparative analysis indicated that our library added 2,400 ESTs and 991 unique sequences to those known for cotton. The unigenes were functionally characterized by gene ontology annotation. We identified 1,339 and 200 unigenes as potential leaf senescence-related genes and transcription factors, respectively. Moreover, nine genes related to leaf senescence and eleven MYB transcription factors were randomly selected for quantitative real-time PCR (qRT-PCR, which revealed that these genes were regulated differentially during senescence. The qRT-PCR for three GhYLSs revealed that these genes express express preferentially in senescent leaves. CONCLUSIONS/SIGNIFICANCE: These EST resources will provide valuable sequence information for gene expression profiling analyses and functional genomics studies to elucidate their roles, as well as for studying the mechanisms of leaf development and senescence in cotton and discovering candidate genes related to important agronomic traits of cotton. These data will also facilitate future whole-genome sequence

  18. 规模化电动汽车和风电协同调度的机组组合问题研究%Unit commitment considering coordinated dispatch of large scale electric vehicles and wind power generation

    Institute of Scientific and Technical Information of China (English)

    汪春; 吴可; 张祥文; 孙海顺; 张聪; 许晓慧

    2015-01-01

    基于电动汽车通过集中控制器与电网交互的模式,考虑集中控制器所辖区域电动汽车负荷每个调度时段的可控特性,提出将集中控制器充电负荷作为机组组合模型的控制变量。通过蒙特卡洛抽样模拟电动汽车并网场景,计算集中控制器的可调度上限值和下限值,建立了规模化电动汽车与风电协同调度的机组组合模型。算例分析结果表明了应用提出的机组组合模型提高风电消纳能力和降低系统运行成本的有效性。%Assuming that all electric vehicles integrated to the grid are managed by aggregators, this paper proposes that the charging load of each EV aggregator can be dispatched within the unit commitment model taking the controllability of the charging of EVs at each dispatched time period into consideration. This can be accomplished by assessing the upper and lower limit of charging load of each EV aggregator based on the grid connected EVs scenarios simulation using Monte Carlo method. A unit commitment (UC) model is proposed for optimal coordination of wind power generation and charging load of EV aggregators. Cases study show that with the proposed UC model the wind abandon can be decreased as well as the cost of operation effectively.

  19. Distributed power generation using microturbines

    CSIR Research Space (South Africa)

    Szewczuk, S

    2008-11-01

    Full Text Available At present, the bulk of the world is electricity is generated in central power stations. This approach, one of `economy of size generates electricity in large power stations and delivers it to load centres via an extensive network of transmission...

  20. Pattern Based Graph Generator

    CERN Document Server

    Shuai, Hong-Han; Yu, Philip S; Shen, Chih-Ya; Chen, Ming-Syan

    2013-01-01

    The importance of graph mining has been widely recognized thanks to a large variety of applications in many areas, while real datasets always play important roles to examine the solution quality and efficiency of a graph mining algorithm. Nevertheless, the size of a real dataset is usually fixed and constrained according to the available resources, such as the efforts to crawl an on-line social network. In this case, employing a synthetic graph generator is a possible way to generate a massive graph (e.g., billions nodes) for evaluating the scalability of an algorithm, and current popular statistical graph generators are properly designed to maintain statistical metrics such as total node degree, degree distribution, diameter, and clustering coefficient of the original social graphs. Nevertheless, in addition to the above metrics, recent studies on graph mining point out that graph frequent patterns are also important to provide useful implications for the corresponding social networking applications, but thi...

  1. Learning to Generate Networks

    CERN Document Server

    Atwood, James

    2014-01-01

    The recent explosion in social network data has stimulated interest in probabilistic models of networks. Such models are appealing because they are empirically grounded; in contrast to more traditional network models, their parameters are estimated from data, and the models are evaluated on how well they represent the data. The exponential random graph model (ERGM, or, alternatively $p^*$) is currently the dominant framework for probabilistic network modeling. Despite their popularity, ERGMs suffer from a very serious flaw: near degeneracy. Briefly, an ERGM fit to a network or set of networks often ends up generating networks that look nothing at all like the training data. It is deeply troubling that the most likely model will generate instances that look nothing like data, and this calls the validity of models into question. In this work, we seek to address the general problem of learning to generate networks that do look like data. This is a large, challenging problem. To gain an understanding, we decompos...

  2. A viable technology to generate third-generation biofuel

    DEFF Research Database (Denmark)

    Singh, Anoop; Olsen, Stig Irving; Nigam, Poonam Singh

    2011-01-01

    First generation biofuels are commercialized at large as the production technologies are well developed. However, to grow the raw materials, there is a great need to compromise with food security, which made first generation biofuels not so much promising. The second generation of biofuels does...... not have direct competition with food but requires several energy intensive processes to produce them and also increase the land use change, which reduces its environmental and economical feasibility. The third generation biofuels production avoids issues with first and second generation biofuels, viz...... of organic waste and carbon dioxide in flue gases for the production of biomass further increases the sustainability of third generation biofuels, as it does minimize greenhouse gases emission and disposal problems....

  3. Steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Beckmann, G.; Gilli, P.V.; Fritz, K.; Lippitsch, J.

    1975-12-02

    A steam generator is disclosed which is particularly adapted to be used in nuclear power plants. A casing is provided with an inlet and outlet to receive and discharge a primary heating fluid from which heat is to be extracted. A pair of tube plates extend across the interior of the casing at the region of the inlet and outlet thereof, and a plurality of tubes extend along the interior of the casing and are connected in parallel between the tube plates with all of the tubes having open ends communicating with the inlet and outlet of the casing so that the primary heating fluid will flow through the interior of the tubes while a fluid in the casing at the exterior of the tubes will extract heat from the primary fluid. The casing has between the tubes at the region of the inlet a superheating chamber and at the region of the outlet a preheating chamber and between the latter chambers an evaporating chamber, the casing receiving water through an inlet at the preheating chamber and discharging superheated steam through an outlet at the superheating chamber. A separator communicates with the evaporating chamber to receive a mixture of steam and water therefrom for separating the steam from the water and for delivering the separated steam to the superheating chamber.

  4. Large reservoirs: Chapter 17

    Science.gov (United States)

    Miranda, Leandro E.; Bettoli, Phillip William

    2010-01-01

    Large impoundments, defined as those with surface area of 200 ha or greater, are relatively new aquatic ecosystems in the global landscape. They represent important economic and environmental resources that provide benefits such as flood control, hydropower generation, navigation, water supply, commercial and recreational fisheries, and various other recreational and esthetic values. Construction of large impoundments was initially driven by economic needs, and ecological consequences received little consideration. However, in recent decades environmental issues have come to the forefront. In the closing decades of the 20th century societal values began to shift, especially in the developed world. Society is no longer willing to accept environmental damage as an inevitable consequence of human development, and it is now recognized that continued environmental degradation is unsustainable. Consequently, construction of large reservoirs has virtually stopped in North America. Nevertheless, in other parts of the world construction of large reservoirs continues. The emergence of systematic reservoir management in the early 20th century was guided by concepts developed for natural lakes (Miranda 1996). However, we now recognize that reservoirs are different and that reservoirs are not independent aquatic systems inasmuch as they are connected to upstream rivers and streams, the downstream river, other reservoirs in the basin, and the watershed. Reservoir systems exhibit longitudinal patterns both within and among reservoirs. Reservoirs are typically arranged sequentially as elements of an interacting network, filter water collected throughout their watersheds, and form a mosaic of predictable patterns. Traditional approaches to fisheries management such as stocking, regulating harvest, and in-lake habitat management do not always produce desired effects in reservoirs. As a result, managers may expend resources with little benefit to either fish or fishing. Some locally

  5. 智能电网——大规模风、光电并网瓶颈问题的解决方案%The smart grid─ the best of all scheme to solve the bottleneck problems of wind power and photoelectric power generation connected with power network on a large scale

    Institute of Scientific and Technical Information of China (English)

    徐娟; 孙大伟

    2012-01-01

    Aiming at the problems of the security and stability of power network caused by load undulation or power quality not good when wind power and photoelectric power generation connected with power network on a large scale.Through analyzing and comparing to find out: the smart grid with powerful capacity,facility and compatibility,con fit multiform power supply to connect with and contain it.The result of research shows that developing the smart grid maybe is the best of all scheme to solve the bottleneck problems of wind power and photoelectric power generation connected with power network on a large scale.%针对大规模风、光发电集中接入电网后产生的负荷波动性及电能质量较差,给电网带来的安全性和稳定性问题,通过分析对比发现,智能电网具有很好的智能性、灵活性和兼容性,不但成功地解决了上述问题还可以适应多种形式的电源接入并能将其成功消纳。研究表明:发展智能电网是解决大规模风、光发电并网瓶颈问题的最佳方案。

  6. CAT-generation of ideals

    CERN Document Server

    Ueckerdt, Torsten

    2010-01-01

    We consider the problem of generating all ideals of a poset. It is a long standing open problem, whether or not the ideals of any poset can be generated in constant amortized time, CAT for short. We refine the tree traversal, a method introduced by Pruesse and Ruskey in 1993, to obtain a CAT-generator for two large classes of posets: posets of interval dimension at most two and so called locally planar posets. This includes all posets for which a CAT-generator was known before. Posets of interval dimension at most two generalize both, interval orders and 2-dimensional posets. Locally planar posets generalize for example posets with a planar cover graph. We apply our results to CAT-generate all $c$-orientations of a planar graph. As a special case this is a CAT-generator for many combinatorial objects like domino and lozenge tilings, planar spanning trees, planar bipartite perfect matchings, Schnyder woods, and others.

  7. Liposome adhesion generates traction stress

    Science.gov (United States)

    Murrell, Michael P.; Voituriez, Raphaël; Joanny, Jean-François; Nassoy, Pierre; Sykes, Cécile; Gardel, Margaret L.

    2014-02-01

    Mechanical forces generated by cells modulate global shape changes required for essential life processes, such as polarization, division and spreading. Although the contribution of the cytoskeleton to cellular force generation is widely recognized, the role of the membrane is considered to be restricted to passively transmitting forces. Therefore, the mechanisms by which the membrane can directly contribute to cell tension are overlooked and poorly understood. To address this, we directly measure the stresses generated during liposome adhesion. We find that liposome spreading generates large traction stresses on compliant substrates. These stresses can be understood as the equilibration of internal, hydrostatic pressures generated by the enhanced membrane tension built up during adhesion. These results underscore the role of membranes in the generation of mechanical stresses on cellular length scales and that the modulation of hydrostatic pressure due to membrane tension and adhesion can be channelled to perform mechanical work on the environment.

  8. Series pid pitch controller of large wind turbines generator

    Directory of Open Access Journals (Sweden)

    Micić Aleksandar D.

    2015-01-01

    Full Text Available For this stable process with oscillatory dynamics, characterized with small damping ratio and dominant transport delay, design of the series PID pitch controller is based on the model obtained from the open-loop process step response, filtered with the second-order Butterworth filter Fbw. Performance of the series PID pitch controller, with the filter Fbw, is analyzed by simulations of the set-point and input/output disturbance responses, including simulations with a colored noise added to the control variable. Excellent performance/robustness tradeoff is obtained, compared to the recently proposed PI pitch controllers and to the modified internal model pitch controller, developed here, which has a natural mechanism to compensate effect of dominant transport delay. [Projekat Ministarstva nauke Republike Srbije, br. III 47016

  9. The generation of large networks from web of science data

    NARCIS (Netherlands)

    Leydesdorff, L.; Khan, G.F.; Bornmann, L.

    2014-01-01

    During the 1990s, one of us developed a series of freeware routines (http://www.leydesdorff.net/indicators) that enable the user to organize downloads from the Web of Science (Thomson Reuters) into a relational database, and then to export matrices for further analysis in various formats (for exampl

  10. Large-scale multimodal transport modelling. Part 1: Demand generation

    CSIR Research Space (South Africa)

    Joubert, JW

    2013-07-01

    Full Text Available between private individuals and commercial vehicles, describing the two distinct processes followed. Section 3 describes the use of free and open network data in the form of OpenStreetMap, and how the data is converted into a MATSim network, where after...), dropping or collecting children from school (e3), shopping (s), leisure (l) and other (o). The inclusion of e3 was justified since many children in South Africa are dropped at school using private vehicles, which have a plausibly significant impact...

  11. Variability in large-scale wind power generation

    DEFF Research Database (Denmark)

    Kiviluoma, Juha; Holttinen, Hannele; Weir, David

    2016-01-01

    load events. The comparison shows regions with low variability (Sweden, Spain and Germany), medium variability (Portugal, Ireland, Finland and Denmark) and regions with higher variability (Quebec, Bonneville Power Administration and Electric Reliability Council of Texas in North America; Gansu, Jilin......The paper demonstrates the characteristics of wind power variability and net load variability in multiple power systems based on real data from multiple years. Demonstrated characteristics include probability distribution for different ramp durations, seasonal and diurnal variability and low net...... and Liaoning in China; and Norway and offshore wind power in Denmark). For regions with low variability, the maximum 1 h wind ramps are below 10% of nominal capacity, and for regions with high variability, they may be close to 30%. Wind power variability is mainly explained by the extent of geographical spread...

  12. Control of Permanent Magnet Synchronous Generator for large wind turbines

    DEFF Research Database (Denmark)

    Busca, Cristian; Stan, Ana-Irina; Stanciu, Tiberiu

    2010-01-01

    converter topology was chosen for design. Parameters from a 2 MW wind turbine were used for system modeling. All the components of the wind turbine system (WTS), except the DC-link and the grid site converter were implemented in MATLAB/Simulink. The pitch controller was used to limit the output power...

  13. The generation of large networks from web of science data

    NARCIS (Netherlands)

    Leydesdorff, L.; Khan, G.F.; Bornmann, L.

    2014-01-01

    During the 1990s, one of us developed a series of freeware routines (http://www.leydesdorff.net/indicators) that enable the user to organize downloads from the Web of Science (Thomson Reuters) into a relational database, and then to export matrices for further analysis in various formats (for exampl

  14. DEVELOPMENT OF A VECTORIAL LASER PLOTTER FOR GENERATING LARGE DRAWING

    OpenAIRE

    HARITH TAHA MOHAMED HUSSAIN

    1991-01-01

    O presente trabalho apresenta um estudo sobre a viabilização de uma traçadora gráfica à laser, de funcionamento vetorial, para a produção de desenhos de grandes dimensões. A grande vantagem deste conceito é a obtenção de elevada velocidade de risco devido às peças móveis de número e dimensões reduzidas. Uma aplicação típica é o risco de encaixe na indústria de confecção. A recente construção de um protótipo no departamento de Engenharia Mecânica da PUC-RJ indicou a viabilidade prática do con...

  15. Design Methodology of Large-scale Thermoelectric Generation

    DEFF Research Database (Denmark)

    Chen, Min; Gao, Junling; Zhu, Junpeng

    2011-01-01

    -thermal-electric-circuit multiphysics behaviors. Firstly, a quasi one-dimension numerical model for the thermal fluids and their non-uniform temperature distribution as the boundary condition for TEMs is implemented in SPICE using electrothermal analogy. Secondly, the electric field calculation of the previously proposed device...... modeling and design scalable, flexible, and programmable. To validate the proposed system model, a TEGS including 8 TEMs is constructed. Through comparisons between simulation results and experimental data, it is clear that the cooptimization of the entire TEGS is enabled by the proposed model....

  16. The generation of large networks from web of science data

    NARCIS (Netherlands)

    Leydesdorff, L.; Khan, G.F.; Bornmann, L.

    2014-01-01

    During the 1990s, one of us developed a series of freeware routines (http://www.leydesdorff.net/indicators) that enable the user to organize downloads from the Web of Science (Thomson Reuters) into a relational database, and then to export matrices for further analysis in various formats (for

  17. Inflow Turbulence Generation Methods

    Science.gov (United States)

    Wu, Xiaohua

    2017-01-01

    Research activities on inflow turbulence generation methods have been vigorous over the past quarter century, accompanying advances in eddy-resolving computations of spatially developing turbulent flows with direct numerical simulation, large-eddy simulation (LES), and hybrid Reynolds-averaged Navier-Stokes–LES. The weak recycling method, rooted in scaling arguments on the canonical incompressible boundary layer, has been applied to supersonic boundary layer, rough surface boundary layer, and microscale urban canopy LES coupled with mesoscale numerical weather forecasting. Synthetic methods, originating from analytical approximation to homogeneous isotropic turbulence, have branched out into several robust methods, including the synthetic random Fourier method, synthetic digital filtering method, synthetic coherent eddy method, and synthetic volume forcing method. This article reviews major progress in inflow turbulence generation methods with an emphasis on fundamental ideas, key milestones, representative applications, and critical issues. Directions for future research in the field are also highlighted.

  18. Estimation and Characteristic Analysis of Large-scale Wind Farm Generation in Cyber Physical Energy System%面向信息物理融合能源系统的大规模风电场发电功率随机特性分析模型与算法

    Institute of Scientific and Technical Information of China (English)

    吴江; 靳晶新; 管晓宏; 谢栋; 卢春明

    2016-01-01

    The variability and uncertainty of wind energy is becoming a huge threat to the security and stability of the grid with high wind penetration. This paper focused on the stochastic dynamic model for aggregated generation of large-scale wind farm in cyber physical energy system, and presented a dynamic system description aggregated generation of wind turbines based on stochastic Burgers equation from near-surface wind field’s dynamics and wind-generation function with uncertainties. Then we developed a particle filter based solutions to estimate theτ-step-ahead generation of this nonlinear dynamic system. Finally, a 30-turbine study case shows that this method is efficient and effective.%随着风电并网容量的迅猛增长,对风电高度不确定性和间歇特性的准确估计与实时分析成为了风电入网迫切需要解决的难题。该文以信息物理融合系统为支撑,利用其多源信息感知与融合的特点,以随机Burgers方程为基础,建立了描述近地风场动态特性及其风电转换过程的随机系统模型。利用粒子滤波算法,实现了大规模风电场发电功率波动性的提前τ步估计与随机特性分析。最后,利用一个30风机风电场算例说明了算法的有效性。

  19. Second harmonic generation microscopy

    DEFF Research Database (Denmark)

    Brüggemann, Dagmar Adeline; Brewer, Jonathan R.; Risbo, Jens

    2010-01-01

    Myofibers and collagen show non-linear optical properties enabling imaging using second harmonic generation (SHG) microscopy. The technique is evaluated for use as a tool for real-time studies of thermally induced changes in thin samples of unfixed and unstained pork. The forward and the backward......-temperature endotherm peak observable in the differential scanning calorimetry (DSC) thermograms. DSC analysis of epimysium, the connective tissue layer that enfold skeletal muscles, produces one large endotherm starting at 57 °C and peaking at 59.5 °C. SHG microscopy of collagen fibers reveals a variability of thermal...

  20. Next-generation sequencing

    DEFF Research Database (Denmark)

    Rieneck, Klaus; Bak, Mads; Jønson, Lars

    2013-01-01

    the feasibility of predicting the fetal KEL1 phenotype using next-generation sequencing (NGS) technology. STUDY DESIGN AND METHODS: The KEL1/2 single-nucleotide polymorphism was polymerase chain reaction (PCR) amplified with one adjoining base, and the PCR product was sequenced using a genome analyzer (GAIIx......, Illumina); several millions of PCR sequences were analyzed. RESULTS: The results demonstrated the feasibility of diagnosing the fetal KEL1 or KEL2 blood group from cell-free DNA purified from maternal plasma. CONCLUSION: This method requires only one primer pair, and the large amount of sequence...

  1. Integration of stochastic generation in power systems

    NARCIS (Netherlands)

    Papaefthymiou, G.

    2007-01-01

    Stochastic Generation is the electrical power production by the use of an uncontrollable prime energy mover, corresponding mainly to renewable energy sources. For the large-scale integration of stochastic generation in power systems, methods are necessary for the modeling of power generation

  2. Integration of stochastic generation in power systems

    NARCIS (Netherlands)

    Papaefthymiou, G.

    2007-01-01

    Stochastic Generation is the electrical power production by the use of an uncontrollable prime energy mover, corresponding mainly to renewable energy sources. For the large-scale integration of stochastic generation in power systems, methods are necessary for the modeling of power generation uncerta

  3. Integration of stochastic generation in power systems

    NARCIS (Netherlands)

    Papaefthymiou, G.

    2007-01-01

    Stochastic Generation is the electrical power production by the use of an uncontrollable prime energy mover, corresponding mainly to renewable energy sources. For the large-scale integration of stochastic generation in power systems, methods are necessary for the modeling of power generation uncerta

  4. Steam turbine overspeed protection scheme after a sudden large -scale thermal power generating units outgoing transmission line interrupted based on zero power facility%零功率装置的发电机组外送线路中断后超速保护方案

    Institute of Scientific and Technical Information of China (English)

    余智

    2012-01-01

    Large - scale thermal power plant is in which output channel is break off, operational units will take place overspeed, even cause the equipment damaged. To avoid the accident happened , after analysis and discussion, considering using the way of zero power facility to generator triping , so as to ensure the safety outage of equipments.%大型火力发电厂在输出通道突然中断的情况下,运行的机组将会发生超速,甚至造成损坏,为避免此类事故的发生,经过分析论证,考虑采用零功率装置方式进行切机,以确保机组设备的安全停运。

  5. Application of Undamaged Operation Process of Preformed Winding Inserting on Large-Sized Direct-Driven Permanent Magnet Generators for Wind Turbines%成型绕组无损嵌线工艺在大型永磁直驱风力发电机中的应用

    Institute of Scientific and Technical Information of China (English)

    袁春龙

    2011-01-01

    Based on the analysis of the construction features of large-sized direct-driven permanent-magnet Generators for wind turbines(DPGW) and insulation damage caused in winding inserting process, a new undamaged operation process of preformed winding inserting was put forward. The results indicated that integrity and reliability of insulating structure got assuring effectively with the use of undamaged operation process.%基于对内定子结构大型永磁直驱风力发电机的结构特点及绕组嵌装过程可能发生绝缘缺陷的分析,提出一种无损嵌线工艺方法.结果表明该嵌线工艺方法可有效保证大型永磁直驱风力发电机定子绝缘结构的完整性和可靠性.

  6. Reusable State Machine Code Generator

    Science.gov (United States)

    Hoffstadt, A. A.; Reyes, C.; Sommer, H.; Andolfato, L.

    2010-12-01

    The State Machine model is frequently used to represent the behaviour of a system, allowing one to express and execute this behaviour in a deterministic way. A graphical representation such as a UML State Chart diagram tames the complexity of the system, thus facilitating changes to the model and communication between developers and domain experts. We present a reusable state machine code generator, developed by the Universidad Técnica Federico Santa María and the European Southern Observatory. The generator itself is based on the open source project architecture, and uses UML State Chart models as input. This allows for a modular design and a clean separation between generator and generated code. The generated state machine code has well-defined interfaces that are independent of the implementation artefacts such as the middle-ware. This allows using the generator in the substantially different observatory software of the Atacama Large Millimeter Array and the ESO Very Large Telescope. A project-specific mapping layer for event and transition notification connects the state machine code to its environment, which can be the Common Software of these projects, or any other project. This approach even allows to automatically create tests for a generated state machine, using techniques from software testing, such as path-coverage.

  7. 大型汽轮发电机定子绕组端部电动力三维有限元计算%The 3D FEM Calculation of Electromagnetic Force on the End Stator Windings of Large Turbo-generator

    Institute of Scientific and Technical Information of China (English)

    胡刚; 张建涛; 李金香

    2013-01-01

    This paper presented a method for calculating the force on the end stator windings by taking a 660MW turbo-generator for an example. Firstly, the FEM mathematic model for calculating 3D end field of large turbo-generator is presented. And a solid model of the end of stator windings of the turbo-generator is built according to the actual shape. Through numerical calculating the distribution of end field at the moment of the maximum short current achieved is gained. Basing on the calculating the force on the end of stator windings and the distribution of the force on the each bar are obtained. The effect of the exciting current on the magnetic force is compared and discussed, which provides some references for the design of the stator end support structures.%  本文以一台660MW汽轮发电机为例,详细阐述了汽轮发电机定子端部电动力的计算方法。首先提出了大型汽轮发电机三维端部磁场的有限元数学模型,并按真实形状建立了汽轮发电机定子绕组端部实体模型。计算得到了三相突然短路时出现电流最大时刻的端部磁场分布,在此基础上得到每根定子线棒所受到的端部电动力及单根线棒的电动力分布规律。讨论比较了励磁电流对定子线棒端部电动力的影响,为发电机端部结构设计提供依据。

  8. Control Method of Static Var Generator to Aid Direct Starting of Large Induction Motor in Offshore Oil-Rig Power System%一种辅助海上油田群电网大型异步电机直接起动的静止无功发生器控制方法

    Institute of Scientific and Technical Information of China (English)

    魏澈; 董宜鹏; 王建丰; 刘国锋; 李强; 谢小荣

    2014-01-01

    The direct starting of large induction motors such as water-injection pumps in an independent offshore oil-rig power system will result in severe problems, for instance, sharp increase of reactive power, deep drop of bus voltage, drop-off of load, or even trip of overloaded generators. To handle these problems, an improved dynamic var control method of static var generator(SVG) was presented. The method, as an improvement on the conventional var/voltage regulation, has newly developed control functions of motor-starting var compensation and switch control, by which, the motor and SVG are controlled to go through the states of pre-starting, start-preparation, motor-starting and start completion successively and smoothly. The proposed method is applied to the Southwest Wei offshore power system on the South China Sea. The simulation results show that it can provide sufficient dynamic var support for the direct starting of large induction motors and the bus voltage is maintained, the safe operation of gas-turbine generator and load is guaranteed.%海上油田群电网由于容量相对较小,当大型异步电动机负载直接起动时,会导致无功需求增加、电压突降、机组过载解列和负荷低压脱扣等问题。提出了一种基于静止无功发生器的改进动态无功控制策略。在常规无功/电压控制基础上,增加电机起动补偿器和切换器功能,控制电机起动过程中各调节器及其参量的切换,实现电机的平稳起动并降低对系统的冲击。控制方法应用于我国南海的涠西南油田群电网。仿真分析表明,该方法能对大型异步电机直接起动提供足够的动态无功支撑,达到稳定电压和保证燃气轮发电机和负荷安全运行的目标。

  9. Electricity generation and health.

    Science.gov (United States)

    Markandya, Anil; Wilkinson, Paul

    2007-09-15

    The provision of electricity has been a great benefit to society, particularly in health terms, but it also carries health costs. Comparison of different forms of commercial power generation by use of the fuel cycle methods developed in European studies shows the health burdens to be greatest for power stations that most pollute outdoor air (those based on lignite, coal, and oil). The health burdens are appreciably smaller for generation from natural gas, and lower still for nuclear power. This same ranking also applies in terms of greenhouse-gas emissions and thus, potentially, to long-term health, social, and economic effects arising from climate change. Nuclear power remains controversial, however, because of public concern about storage of nuclear waste, the potential for catastrophic accident or terrorist attack, and the diversion of fissionable material for weapons production. Health risks are smaller for nuclear fusion, but commercial exploitation will not be achieved in time to help the crucial near-term reduction in greenhouse-gas emissions. The negative effects on health of electricity generation from renewable sources have not been assessed as fully as those from conventional sources, but for solar, wind, and wave power, such effects seem to be small; those of biofuels depend on the type of fuel and the mode of combustion. Carbon dioxide (CO2) capture and storage is increasingly being considered for reduction of CO2 emissions from fossil fuel plants, but the health effects associated with this technology are largely unquantified and probably mixed: efficiency losses mean greater consumption of the primary fuel and accompanying increases in some waste products. This paper reviews the state of knowledge regarding the health effects of different methods of generating electricity.

  10. Large Databases in Astronomy

    Science.gov (United States)

    Szalay, Alexander S.; Gray, Jim; Kunszt, Peter; Thakar, Anirudha; Slutz, Don

    The next-generation astronomy digital archives will cover most of the sky at fine resolution in many wavelengths, from X-rays through ultraviolet, optical, and infrared. The archives will be stored at diverse geographical locations. The intensive use of advanced data archives will enable astronomers to explore their data interactively. Data access will be aided by multidimensional spatial and attribute indices. The data will be partitioned in many ways. Small tag indices consisting of the most popular attributes will accelerate frequent searches. Splitting the data among multiple servers will allow parallel, scalable I/O and parallel data analysis. Hashing techniques will allow efficient clustering, and pair-wise comparison algorithms that should parallelize nicely. Randomly sampled subsets will allow debugging otherwise large queries at the desktop. Central servers will operate a data pump to support sweep searches touching most of the data. The anticipated queries will require special operators related to angular distances and complex similarity tests of object properties, like shapes, colors, velocity vectors, or temporal behaviors. These issues pose interesting data management challenges.

  11. Gearless wind power generator

    Energy Technology Data Exchange (ETDEWEB)

    Soederlund, L.; Ridanpaeae, P.; Vihriaelae, H.; Peraelae, R. [Tampere Univ. of Technology (Finland). Lab. of Electricity and Magnetism

    1998-10-01

    In the project a 100 kW axial flux permanent magnet wind power generator has been designed. The toroidal stator with air gap winding is placed between two rotating discs with permanent magnets. The magnet material is NdBFe due to its excellent magnetic properties compared to other materials. This type of topology enables a very large number of poles compared to conventional machine of the same size. A large number of poles is required to achieve a low rotational speed and consequently a direct driven system. The stator winding is formed by rectangular coils. The end winding is very short leading to small resistive losses. On the other hand, the absence of iron teeth causes eddy current losses in the conductors. These can be restricted to an acceptable level by keeping the wire diameter and flux density small. This means that the number of phases should be large. Several independent three phase systems may be used. The toothless stator also means that the iron losses are small and there exists no cogging torque

  12. Adding large EM stack support

    KAUST Repository

    Holst, Glendon

    2016-12-01

    Serial section electron microscopy (SSEM) image stacks generated using high throughput microscopy techniques are an integral tool for investigating brain connectivity and cell morphology. FIB or 3View scanning electron microscopes easily generate gigabytes of data. In order to produce analyzable 3D dataset from the imaged volumes, efficient and reliable image segmentation is crucial. Classical manual approaches to segmentation are time consuming and labour intensive. Semiautomatic seeded watershed segmentation algorithms, such as those implemented by ilastik image processing software, are a very powerful alternative, substantially speeding up segmentation times. We have used ilastik effectively for small EM stacks – on a laptop, no less; however, ilastik was unable to carve the large EM stacks we needed to segment because its memory requirements grew too large – even for the biggest workstations we had available. For this reason, we refactored the carving module of ilastik to scale it up to large EM stacks on large workstations, and tested its efficiency. We modified the carving module, building on existing blockwise processing functionality to process data in manageable chunks that can fit within RAM (main memory). We review this refactoring work, highlighting the software architecture, design choices, modifications, and issues encountered.

  13. Structured grid generator on parallel computers

    Energy Technology Data Exchange (ETDEWEB)

    Muramatsu, Kazuhiro; Murakami, Hiroyuki; Higashida, Akihiro; Yanagisawa, Ichiro

    1997-03-01

    A general purpose structured grid generator on parallel computers, which generates a large-scale structured grid efficiently, has been developed. The generator is applicable to Cartesian, cylindrical and BFC (Boundary-Fitted Curvilinear) coordinates. In case of BFC grids, there are three adaptable topologies; L-type, O-type and multi-block type, the last of which enables any combination of L- and O-grids. Internal BFC grid points can be automatically generated and smoothed by either algebraic supplemental method or partial differential equation method. The partial differential equation solver is implemented on parallel computers, because it consumes a large portion of overall execution time. Therefore, high-speed processing of large-scale grid generation can be realized by use of parallel computer. Generated grid data are capable to be adjusted to domain decomposition for parallel analysis. (author)

  14. Fast large-scale reionization simulations

    NARCIS (Netherlands)

    Thomas, Rajat M.; Zaroubi, Saleem; Ciardi, Benedetta; Pawlik, Andreas H.; Labropoulos, Panagiotis; Jelic, Vibor; Bernardi, Gianni; Brentjens, Michiel A.; de Bruyn, A. G.; Harker, Geraint J. A.; Koopmans, Leon V. E.; Pandey, V. N.; Schaye, Joop; Yatawatta, Sarod; Mellema, G.

    2009-01-01

    We present an efficient method to generate large simulations of the epoch of reionization without the need for a full three-dimensional radiative transfer code. Large dark-matter-only simulations are post-processed to produce maps of the redshifted 21-cm emission from neutral hydrogen. Dark matter h

  15. Fast large-scale reionization simulations

    NARCIS (Netherlands)

    Thomas, Rajat M.; Zaroubi, Saleem; Ciardi, Benedetta; Pawlik, Andreas H.; Labropoulos, Panagiotis; Jelic, Vibor; Bernardi, Gianni; Brentjens, Michiel A.; de Bruyn, A. G.; Harker, Geraint J. A.; Koopmans, Leon V. E.; Pandey, V. N.; Schaye, Joop; Yatawatta, Sarod; Mellema, G.

    2009-01-01

    We present an efficient method to generate large simulations of the epoch of reionization without the need for a full three-dimensional radiative transfer code. Large dark-matter-only simulations are post-processed to produce maps of the redshifted 21-cm emission from neutral hydrogen. Dark matter

  16. Generational Dynamics and Librarianship: Managing Generation X.

    Science.gov (United States)

    Cooper, Julie F.; Cooper, Eric A.

    1998-01-01

    Explores the abilities of Generation X (individuals born 1961 to 1981) librarians to respond to the evolving needs of society. Highlights include age demographics, generational attributes, technology, and the seniority system. (PEN)

  17. Cogeneration of power, heat and cool using an emergency Diesel electric generator in large buildings and a case study%大型建筑中应用应急柴油发电机实现冷热电三联供及其实例分析

    Institute of Scientific and Technical Information of China (English)

    卢智利 卢智利

    2001-01-01

    介绍了一种新型的高效节能中央空调冷暖系统一自备发电、余热利用及热 泵冷暖系统。该系统充分发挥了大型建筑必备设备一自备电源应急柴油发电机的作用,使一次能源在使用中更加符合热力学的原理;该系统不追求某一种机组的高COP,而是利用各种设备的优点,有机匹配,以求一年中最高效的节能。通过与三种常规冷暖系统的一次能源利用率比较,得出该新型冷暖系统的一次能源利用率比三种常规冷暖系统的一次能源利用率高27.88%~104.6%以上.并通过实例计算了采用该系统的某大型广场的全年经济效益。%In large and medium-sized cities, where there are no heat supply networks of steam or hot-water available and coal-fired systems are not allowed to be used in consideration of air quality control, three basic types of the central air-conditioning system can be used in large buildings: (1) the system consisting of a water chiller and an electric heating boiler or an oil-fired boiler; (2) the air-cooled heat pump; (3) the direct-fired LiBr absorption chiller. Based on an analysis of primary energy efficiency of the three types of central air-conditioning systems, a new type of high-performance, energy-saving central air-conditioning system was presented. This system brings the function of the emergency Diesel-electric generator necessary to large buildings into full play and takes advantage of other installations in the system to attain a higher energy utilization efficiency. Compared with the conventional systems, the primary energy efficiency COP of the new type central air-conditioning system is increased by over 28%. By a case study, the annual profit of a large building using this type of system was calculated.

  18. Dynalight Next Generation

    DEFF Research Database (Denmark)

    Jørgensen, Bo Nørregaard; Ottosen, Carl-Otto; Dam-Hansen, Carsten;

    2016-01-01

    The project aims to develop the next generation of energy cost-efficient artificial lighting control that enables greenhouse growers to adapt their use of artificial lighting dynamically to fluctuations in the price of electricity. This is a necessity as fluctuations in the price of electricity can...... be so large that it directly affects the production costs. The project results show that the newly developed lighting control software, DynaLight NG, allows greenhouse growers to adapt their use of artificial lighting to market variations in electricity prices without negative impacts on plant quality...... or production time. The electricity savings that DynaLight NG can achieve depends on the installed lamp type. When used together with conventional SON-T lamps DynaLight NG can achieve an electricity savings of 25% compared to traditional artificial lighting control. The project results also show that shifting...

  19. A Clustering Graph Generator

    Energy Technology Data Exchange (ETDEWEB)

    Winlaw, Manda [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); De Sterck, Hans [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sanders, Geoffrey [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-26

    In very simple terms a network can be de ned as a collection of points joined together by lines. Thus, networks can be used to represent connections between entities in a wide variety of elds including engi- neering, science, medicine, and sociology. Many large real-world networks share a surprising number of properties, leading to a strong interest in model development research and techniques for building synthetic networks have been developed, that capture these similarities and replicate real-world graphs. Modeling these real-world networks serves two purposes. First, building models that mimic the patterns and prop- erties of real networks helps to understand the implications of these patterns and helps determine which patterns are important. If we develop a generative process to synthesize real networks we can also examine which growth processes are plausible and which are not. Secondly, high-quality, large-scale network data is often not available, because of economic, legal, technological, or other obstacles [7]. Thus, there are many instances where the systems of interest cannot be represented by a single exemplar network. As one example, consider the eld of cybersecurity, where systems require testing across diverse threat scenarios and validation across diverse network structures. In these cases, where there is no single exemplar network, the systems must instead be modeled as a collection of networks in which the variation among them may be just as important as their common features. By developing processes to build synthetic models, so-called graph generators, we can build synthetic networks that capture both the essential features of a system and realistic variability. Then we can use such synthetic graphs to perform tasks such as simulations, analysis, and decision making. We can also use synthetic graphs to performance test graph analysis algorithms, including clustering algorithms and anomaly detection algorithms.

  20. Next generation toroidal devices

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, Shoichi [Princeton Plasma Physics Lab., Princeton Univ., NJ (United States)

    1998-10-01

    A general survey of the possible approach for the next generation toroidal devices was made. Either surprisingly or obviously (depending on one`s view), the technical constraints along with the scientific considerations lead to a fairly limited set of systems for the most favorable approach for the next generation devices. Specifically if the magnetic field strength of 5 T or above is to be created by superconducting coils, it imposes minimum in the aspect ratio for the tokamak which is slightly higher than contemplated now for ITER design. The similar technical constraints make the minimum linear size of a stellarator large. Scientifically, it is indicated that a tokamak of 1.5 times in the linear dimension should be able to produce economically, especially if a hybrid reactor is allowed. For the next stellarator, it is strongly suggested that some kind of helical axis is necessary both for the (almost) absolute confinement of high energy particles and high stability and equilibrium beta limits. The author still favors a heliac most. Although it may not have been clearly stated in the main text, the stability afforded by the shearless layer may be exploited fully in a stellarator. (author)

  1. Research and Application on Lightning Protection Grounding Technology for Large Scale Photovol-taic Power Generation System in Mountainous Areas%山区大型光伏发电系统防雷接地技术探究与应用

    Institute of Scientific and Technical Information of China (English)

    孙录贵

    2015-01-01

    Photovoltaic power generation system is based on a film area of solar panels. In order to avoid the waste of land resources,generally large-scale solar photovoltaic generation stations are built on the hillside far away from the town,where is empty,without high-buildings,in high risk area of lightning.It is especially important to make sure the quality of lightning protection earthing electrodes for the electrical resistivity of mountains soil is very high ,fur-thermore it with largescope of radiation,much electrical equipment in power station.In this article,explored the pho-tovoltaic power generation system on the slope of the high resistance of grounding technology theory method by twen-ty MW ground actual problems in the first phase of the photovoltaic powers station project in Xuanyang village Xieji town Yongqiao district. Make the photovoltaic power grounding system in accordance with the requirements of the drawings design basis.Achieve"adjust measures to local conditions,economic and reasonable". Finally the popular-ization and application of the conclution can be maken.%光伏发电系统需要成片区的太阳能电池板作为基础,为了尽量减小对土地的浪费,大型太阳能光伏发电站往往都建设在偏离城镇的山坡上,环境空旷,周边没有高大建筑物防护,其本身就处于雷击高风险区域,而且山区土壤电阻率较高,辐射范围大,电站内电气设备较多,因而确保防雷接地质量尤为重要.该文通过分析埇桥区谢集乡宣杨村20MW地面光伏电站项目一期工程遇到的实际问题,探究在高阻区的山坡上完成光伏发电系统防雷接地技术的方法,使光伏发电接地系统在符合图纸设计要求的基础上,做到"因地制宜、经济合理"并加以推广运用.

  2. Distributed generation induction and permanent magnet generators

    CERN Document Server

    Lai, L

    2007-01-01

    Distributed power generation is a technology that could help to enable efficient, renewable energy production both in the developed and developing world. It includes all use of small electric power generators, whether located on the utility system, at the site of a utility customer, or at an isolated site not connected to the power grid. Induction generators (IGs) are the cheapest and most commonly used technology, compatible with renewable energy resources. Permanent magnet (PM) generators have traditionally been avoided due to high fabrication costs; however, compared with IGs they are more reliable and productive. Distributed Generation thoroughly examines the principles, possibilities and limitations of creating energy with both IGs and PM generators. It takes an electrical engineering approach in the analysis and testing of these generators, and includes diagrams and extensive case study examples o better demonstrate how the integration of energy sources can be accomplished. The book also provides the ...

  3. Talkin' 'bout My Generation

    Science.gov (United States)

    Rickes, Persis C.

    2010-01-01

    The monikers are many: (1) "Generation Y"; (2) "Echo Boomers"; (3) "GenMe"; (4) the "Net Generation"; (5) "RenGen"; and (6) "Generation Next". One name that appears to be gaining currency is "Millennials," perhaps as a way to better differentiate the current generation from its predecessor, Generation X. Millennials are those individuals born…

  4. Large Neighborhood Search

    DEFF Research Database (Denmark)

    Pisinger, David; Røpke, Stefan

    2010-01-01

    Heuristics based on large neighborhood search have recently shown outstanding results in solving various transportation and scheduling problems. Large neighborhood search methods explore a complex neighborhood by use of heuristics. Using large neighborhoods makes it possible to find better...... candidate solutions in each iteration and hence traverse a more promising search path. Starting from the large neighborhood search method,we give an overview of very large scale neighborhood search methods and discuss recent variants and extensions like variable depth search and adaptive large neighborhood...... search....

  5. VSX: The Next Generation

    Science.gov (United States)

    Watson, C. L.

    2012-06-01

    (Abstract only) The AAVSO International Variable Star Index (VSX), the most comprehensive and up-to-date assemblage of publicly-maintained variable star data on the planet, will be undergoing a major overhaul in the coming year to greatly improve the database design, as well as the Web-based user interface. Five years after its official launch, VSX has evolved into an essential component of the AAVSO enterprise information architecture, tightly integrated with many of the technical organization’s other mission-critical processes. However, its unique configuration and functionality are largely based on decades-old data formats and outmoded Web methodologies which will generally not scale well under the anticipated deluge of data from large-scale synoptic surveys. Here, we present the justifications and vision for VSX 2.0, the next generation of this indispensable research tool, including overviews of the creation of a brand new, fully-normalized, database schema, and the ground-up redesign of the front-end Web interface.

  6. Next-Generation Pathology.

    Science.gov (United States)

    Caie, Peter D; Harrison, David J

    2016-01-01

    The field of pathology is rapidly transforming from a semiquantitative and empirical science toward a big data discipline. Large data sets from across multiple omics fields may now be extracted from a patient's tissue sample. Tissue is, however, complex, heterogeneous, and prone to artifact. A reductionist view of tissue and disease progression, which does not take this complexity into account, may lead to single biomarkers failing in clinical trials. The integration of standardized multi-omics big data and the retention of valuable information on spatial heterogeneity are imperative to model complex disease mechanisms. Mathematical modeling through systems pathology approaches is the ideal medium to distill the significant information from these large, multi-parametric, and hierarchical data sets. Systems pathology may also predict the dynamical response of disease progression or response to therapy regimens from a static tissue sample. Next-generation pathology will incorporate big data with systems medicine in order to personalize clinical practice for both prognostic and predictive patient care.

  7. Hazardous Waste Generators

    Data.gov (United States)

    Vermont Center for Geographic Information — The HazWaste database contains generator (companies and/or individuals) site and mailing address information, waste generation, the amount of waste generated etc. of...

  8. A third generation personality test

    OpenAIRE

    Sjöberg, Lennart

    2010-01-01

    The development of personality testing in the workplace has undergone three phases. The first generation of tests, such as Cattell’s 16 PF and the British test OPQ, was characterized by complex systems for the description of the personality. These systems were simplified in part by the following generation of the test, which was based on the five factor model but that model was simple only at the horizontal level. Beneath the five main factors were a large number of ancillary factors, usually...

  9. Comix, a New Matrix Element Generator

    Energy Technology Data Exchange (ETDEWEB)

    Gleisberg, Tanju; /SLAC; Hoche, Stefan; /Durham U., IPPP

    2008-09-03

    We present a new tree-level matrix element generator, based on the color dressed Berends-Giele recursive relations. We discuss two new algorithms for phase space integration, dedicated to be used with large multiplicities and color sampling.

  10. Large Pelagics Intercept Survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Large Pelagics Intercept Survey (LPIS) is a dockside survey of private and charterboat captains who have just completed fishing trips directed at large pelagic...

  11. Power Generation for River and Tidal Generators

    Energy Technology Data Exchange (ETDEWEB)

    Muljadi, Eduard [National Renewable Energy Lab. (NREL), Golden, CO (United States); Wright, Alan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Gevorgian, Vahan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Donegan, James [Ocean Renewable Power Company (ORPC), Portland, ME (United States); Marnagh, Cian [Ocean Renewable Power Company (ORPC), Portland, ME (United States); McEntee, Jarlath [Ocean Renewable Power Company (ORPC), Portland, ME (United States)

    2016-06-01

    Renewable energy sources are the second largest contributor to global electricity production, after fossil fuels. The integration of renewable energy continued to grow in 2014 against a backdrop of increasing global energy consumption and a dramatic decline in oil prices during the second half of the year. As renewable generation has become less expensive during recent decades, and it becomes more accepted by the global population, the focus on renewable generation has expanded from primarily wind and solar to include new types with promising future applications, such as hydropower generation, including river and tidal generation. Today, hydropower is considered one of the most important renewable energy sources. In river and tidal generation, the input resource flow is slower but also steadier than it is in wind or solar generation, yet the level of water turbulent flow may vary from one place to another. This report focuses on hydrokinetic power conversion.

  12. Keystream Generator Based On Simulated Annealing

    Directory of Open Access Journals (Sweden)

    Ayad A. Abdulsalam

    2011-01-01

    Full Text Available Advances in the design of keystream generator using heuristic techniques are reported. A simulated annealing algorithm for generating random keystream with large complexity is presented. Simulated annealing technique is adapted to locate these requirements. The definitions for some cryptographic properties are generalized, providing a measure suitable for use as an objective function in a simulated annealing algorithm, seeking randomness that satisfy both correlation immunity and the large linear complexity. Results are presented demonstrating the effectiveness of the method.

  13. Large volume cryogenic silicon detectors

    Energy Technology Data Exchange (ETDEWEB)

    Braggio, C. [Dipartimento di Fisica, Universita di Padova, via Marzolo 8, 35131 Padova (Italy); Boscardin, M. [Fondazione Bruno Kessler (FBK), via Sommarive 18, I-38100 Povo (Italy); Bressi, G. [INFN sez. di Pavia, via Bassi 6, 27100 Pavia (Italy); Carugno, G.; Corti, D. [INFN sez. di Padova, via Marzolo 8, 35131 Padova (Italy); Galeazzi, G. [INFN lab. naz. Legnaro, viale dell' Universita 2, 35020 Legnaro (Italy); Zorzi, N. [Fondazione Bruno Kessler (FBK), via Sommarive 18, I-38100 Povo (Italy)

    2009-12-15

    We present preliminary measurements for the development of a large volume silicon detector to detect low energy and low rate energy depositions. The tested detector is a one cm-thick silicon PIN diode with an active volume of 31 cm{sup 3}, cooled to the liquid helium temperature to obtain depletion from thermally-generated free carriers. A thorough study has been done to show that effects of charge trapping during drift disappears at a bias field value of the order of 100V/cm.

  14. Fiber optical magnetic field sensor for power generator monitoring

    Science.gov (United States)

    Willsch, Michael; Bosselmann, Thomas; Villnow, Michael

    2014-05-01

    Inside of large electrical engines such as power generators and large drives, extreme electric and magnetic fields can occur which cannot be measured electrically. Novel fiber optical magnetic field sensors are being used to characterize the fields and recognize inner faults of large power generators.

  15. Concept For Generation Of Long Pseudorandom Sequences

    Science.gov (United States)

    Wang, C. C.

    1990-01-01

    Conceptual very-large-scale integrated (VLSI) digital circuit performs exponentiation in finite field. Algorithm that generates unusually long sequences of pseudorandom numbers executed by digital processor that includes such circuits. Concepts particularly advantageous for such applications as spread-spectrum communications, cryptography, and generation of ranging codes, synthetic noise, and test data, where usually desirable to make pseudorandom sequences as long as possible.

  16. Initial Conditions for Large Cosmological Simulations

    CERN Document Server

    Prunet, S; Aubert, D; Pogosyan, D; Teyssier, R; Gottlöber, S

    2008-01-01

    This technical paper describes a software package that was designed to produce initial conditions for large cosmological simulations in the context of the Horizon collaboration. These tools generalize E. Bertschinger's Grafic1 software to distributed parallel architectures and offer a flexible alternative to the Grafic2 software for ``zoom'' initial conditions, at the price of large cumulated cpu and memory usage. The codes have been validated up to resolutions of 4096^3 and were used to generate the initial conditions of large hydrodynamical and dark matter simulations. They also provide means to generate constrained realisations for the purpose of generating initial conditions compatible with, e.g. the local group, or the SDSS catalog.

  17. Minding the Generation Gap

    Science.gov (United States)

    Field, John

    2011-01-01

    Generational conflict is back. After years of relative silence, and mutual ignorance, the young and old are once more at war. With youth unemployment high on the political agenda, the fortunes of the "jobless generation" are being contrasted with those of the "golden generation" of baby boomers, but is one generation really…

  18. Work Values across Generations

    Science.gov (United States)

    Hansen, Jo-Ida C.; Leuty, Melanie E.

    2012-01-01

    Mainstream publication discussions of differences in generational cohorts in the workplace suggest that individuals of more recent generations, such as Generation X and Y, have different work values than do individuals of the Silent and Baby Boom generations. Although extant research suggests that age may influence work values, few of the…

  19. Talkin' 'bout My Generation

    Science.gov (United States)

    Rickes, Persis C.

    2010-01-01

    The monikers are many: (1) "Generation Y"; (2) "Echo Boomers"; (3) "GenMe"; (4) the "Net Generation"; (5) "RenGen"; and (6) "Generation Next". One name that appears to be gaining currency is "Millennials," perhaps as a way to better differentiate the current generation from its…

  20. Work Values across Generations

    Science.gov (United States)

    Hansen, Jo-Ida C.; Leuty, Melanie E.

    2012-01-01

    Mainstream publication discussions of differences in generational cohorts in the workplace suggest that individuals of more recent generations, such as Generation X and Y, have different work values than do individuals of the Silent and Baby Boom generations. Although extant research suggests that age may influence work values, few of the…