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Sample records for large 2400mwth generation

  1. Development and characterization of the control assembly system for the large 2400 MWth Generation IV gas-cooled fast reactor

    International Nuclear Information System (INIS)

    Girardin, G.; Rimpault, G.; Morin, F.; Bosq, J.C.; Coddington, P.; Mikityuk, K.; Chawla, R.

    2008-01-01

    The present paper is related to the design and neutronic characterization of the principal control assembly system for the reference large (2400 MWth) Generation IV gas-cooled fast reactor (GFR), which makes use of ceramic-ceramic (CERCER) plate-type fuel-elements with (U-Pu) carbide fuel contained within a SiC inert matrix. For the neutronic calculations, the deterministic code system ERANOS-2.0 has been used, in association with a full core model including a European fast reactor (EFR)-type pattern for the control assemblies as a starting point. More specifically, the core contains a total of 33 control (control system device: CSD) and safety (diverse safety device: DSD) assemblies implemented in three banks. In the design of the new control assembly system, particular attention was given to the heat generation within the assemblies, so that both neutronic and thermal-hydraulic constraints could be appropriately accounted for. The thermal-hydraulic calculations have been performed with the code COPERNIC, significant coolant mass flow rates being found necessary to maintain acceptable cladding temperatures of the absorber pins. Complementary to the design study, neutronic investigations have been performed to assess the impact of the control assemblies in the GFR core in greater detail (rod interactions, shift of the flux, peaking factors, etc.). Thus, considerable shadowing effects have been observed between the first bank and the safety bank, as also between individual assemblies within the first bank. Large anti-shadowing effects also occur, the most prominent being that between the two CSD banks, where the total assembly worth is almost doubled in comparison to the sum of the individual values. Additional investigations have been performed and, in this context, it has been found that computation of the first-order eigenvalue and the eigenvalue separation is a robust tool to anticipate control assembly interactions in a large fast-spectrum core. One interesting

  2. Achievement of the level 1 PSA in support to the CEA 2400 MWth gas-cooled fast reactor

    International Nuclear Information System (INIS)

    Balmain, M.; Bassi, C.; Azria, P.

    2012-01-01

    Within Generation IV International Forum, the CEA has developed since 2006 a Level 1 PSA to support the design of the 2400 MWth GFR (Gas-cooled Fast Reactor). A first period, with insights published in 2008, consisted in a model with few initiators representative of medium and high pressure situations, those used for the deterministic design of the Decay Heat Removal (DHR) dedicated loops. In a second period, an iterative work reached the probabilistic targets used for generation III reactors, with prior use of normal loops, and increase of DHR reliability in high pressure conditions. The PSA team covered all the internal initiators, and supported the design of components with instrumentation and control and electrical supplies, and the shutdown operating modes of secondary, tertiary circuits, with possible re-alignment to dedicated DHR loops. Besides, the completed PSA integrated more realistic success criteria than the preliminary model and than the deterministic approach, thanks to CATHARE2 code. In case of loss of Forced Convection, the probability of success of the Natural Convection DHR was assessed by a reliability method for passive systems. The paper underlines the PSA methodology knowledge from the EDF expertise, the improvements co-developed with CEA, and the iteration design-PSA-design. (authors)

  3. Reliability analysis of 2400 MWth gas-cooled fast reactor natural circulation decay heat removal system

    International Nuclear Information System (INIS)

    Marques, M.; Bassi, C.; Bentivoglio, F.

    2012-01-01

    In support to a PSA (Probability Safety Assessment) performed at the design level on the 2400 MWth Gas-cooled Fast Reactor, the functional reliability of the decay heat removal system (DHR) working in natural circulation has been estimated in two transient situations corresponding to an 'aggravated' Loss of Flow Accident (LOFA) and a Loss of Coolant Accident (LOCA). The reliability analysis was based on the RMPS methodology. Reliability and global sensitivity analyses use uncertainty propagation by Monte Carlo techniques. The DHR system consists of 1) 3 dedicated DHR loops: the choice of 3 loops (3*100% redundancy) is made in assuming that one could be lost due to the accident initiating event (break for example) and that another one must be supposed unavailable (single failure criterion); 2) a metallic guard containment enclosing the primary system (referred as close containment), not pressurized in normal operation, having a free volume such as the fast primary helium expansion gives an equilibrium pressure of 1.0 MPa, in the first part of the transient (few hours). Each dedicated DHR loop designed to work in forced circulation with blowers or in natural circulation, is composed of 1) a primary loop (cross-duct connected to the core vessel), with a driving height of 10 meters between core and DHX mid-plan; 2) a secondary circuit filled with pressurized water at 1.0 MPa (driving height of 5 meters for natural circulation DHR); 3) a ternary pool, initially at 50 C. degrees, whose volume is determined to handle one day heat extraction (after this time delay, additional measures are foreseen to fill up the pool). The results obtained on the reliability of the DHR system and on the most important input parameters are very different from one scenario to the other showing the necessity for the PSA to perform specific reliability analysis of the passive system for each considered scenario. The analysis shows that the DHR system working in natural circulation is

  4. Large hydropower generating units

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    This document presents the Brazilian experience with the design, fabrication, construction, commissioning and operation of large scale and generation capacity unities. The experience had been acquired with the implementation of Itumbiara, Paulo Afonso IV, Tucurui, Itaipu and Xingo power plants, which are among the largest world unities.

  5. Control rod shadowing and anti-shadowing effects in a large gas-cooled fast reactor

    International Nuclear Information System (INIS)

    Girardin, G.; Chawla, R.; Rimpault, G.; Coddington, P.

    2007-01-01

    An investigation of control rod shadowing and anti-shadowing (interaction) effects has been carried out in the context of a design study of the control rod pattern for the large 2400 MWth Generation IV Gas-cooled Fast Reactor (GFR). For the calculations, the deterministic code system ERANOS-2.0 has been used, in association with a full core model including a European Fast Reactor (EFR)-type pattern for the control rods. More specifically, the core contains a total of 33 control (CSD) and safety (DSD) rods implemented in three banks: -1) a first bank of 6 CSD rods, placed at 64 cm from core centre in the inner fuel zone (Pu content 16.3 % vol.), -2) a safety bank consisting of 9 DSD rods, at an average distance of 118 cm, and -3) a third bank with 18 CSD rods, placed at 171 cm, i.e. at the interface between the inner and outer (Pu content 19.2 % vol.) core regions. Each control rod has been modelled as a homogeneous material containing 90%-enriched B 4 C, steel and helium. Considerable shadowing effects have been observed between the first bank and the safety bank, as also between individual rods within the first bank. Large anti-shadowing effects take place in an even greater number of the studied rod configurations. The largest interaction is between the two CSD banks, the anti-shadowing value being 46% in this case, implying that the total rod worth is increased by a factor of almost 2 when compared to the sum of the individual bank values. Additional investigations have been performed, in particular the computation of the first order eigenvalue and the eigenvalue separation. The main finding is that the interactions are lower when one of the control rod banks is located at a radial position corresponding to half the core radius. (authors)

  6. Gas cooled fast reactor 2400 MWTh, status on the conceptual design studies and preliminary safety analysis

    International Nuclear Information System (INIS)

    Malo, J.Y.; Alpy, N.; Bentivoglio, F.

    2009-01-01

    The Gas cooled Fast Reactor (GFR) is considered by the French Commissariat a l'Energie Atomique as a promising concept, combining the benefits of fast spectrum and high temperature, using Helium as coolant. A status on the GFR preliminary viability was made at the end of 2007, ending the pre-conceptual design phase. A consistent overall systems arrangement was proposed and a preliminary safety analysis based on operating transient calculations and a simplified PSA had established a global confidence in the feasibility and safety of this baseline concept. Its potential for attractive performances had been pointed out. Compare to the more mature Sodium Fast Reactor technology, no demonstrator has ever been built and the feasibility demonstration will required a longer lead time. The next main project milestone is related to the GFR viability, scheduled in 2012. The current studies consist in revisiting the reactor reference design options as selected at the end of 2007. Most of them are being consolidated by going more in depth in the analysis. Some possible alternatives are assessed. The paper will give a status on the last studies performed on the core design and corresponding neutronics and cycle performance, the Decay Heat Removal strategy and preliminary safety analysis, systems design and balance of plant... This paper is complementary to the Icapp'09 papers 9062 dealing with the Gas cooled Fast Reactor Demonstrator ALLEGRO and 9378 related to GFR transients analysis. (author)

  7. Development of the control assembly pattern and dynamic analysis of the Generation IV large gas-cooled fast reactor (GFR)

    Energy Technology Data Exchange (ETDEWEB)

    Girardin, G.

    2009-07-15

    During the past ten years, different independent factors, such as the rapidly increasing worldwide demand in energy, societal concerns about greenhouse gas emissions, and the high and volatile prices for fossil fuels, have contributed to the renewed interest in nuclear technology. In this context, the Generation IV International Forum (GIF) launched the initiative to collaborate on the research and development efforts needed for the next generation of nuclear reactors. A particular goal set for Generation IV systems is closure of the nuclear fuel cycle; they are expected to offer a better utilization of natural resources, as also a minimization of long-lived radioactive wastes. Among the systems selected by the GIF, the Gas-cooled Fast Reactor (GFR) is a highly innovative system with advanced fuel geometry and materials. The principal aim of the present research is to develop and qualify the control assembly (CA) pattern and corresponding CA implementation scheme for the 2400 MWth reference GFR design. The work has been carried out in three successive phases: (1) validation of the neutronics tools, (2) the CA pattern development and related static analysis, and (3) dynamic core behaviour studies for hypothetical CA driven transients. The deterministic code system ERANOS and its associated nuclear data libraries for fast reactors were developed and validated for sodium-cooled reactors. In order to validate ERANOS for GFR applications, a systematic reanalysis of the GFR-relevant integral data generated at PSI during the GCFR-PROTEUS experimental program of the 1970’s was undertaken. The reference PROTEUS test lattice has been analyzed with ERANOS-2.0 and its associated, adjusted nuclear data library ERALIB1. Benchmark calculations were performed with the Monte Carlo code MCNPX, allowing one to both check the deterministic results and to analyze the sensitivity to different modern data libraries. For the main reaction rate ratios, the new analysis of the GCFR

  8. Development of the control assembly pattern and dynamic analysis of the Generation IV large gas-cooled fast reactor (GFR)

    International Nuclear Information System (INIS)

    Girardin, G.

    2009-07-01

    During the past ten years, different independent factors, such as the rapidly increasing worldwide demand in energy, societal concerns about greenhouse gas emissions, and the high and volatile prices for fossil fuels, have contributed to the renewed interest in nuclear technology. In this context, the Generation IV International Forum (GIF) launched the initiative to collaborate on the research and development efforts needed for the next generation of nuclear reactors. A particular goal set for Generation IV systems is closure of the nuclear fuel cycle; they are expected to offer a better utilization of natural resources, as also a minimization of long-lived radioactive wastes. Among the systems selected by the GIF, the Gas-cooled Fast Reactor (GFR) is a highly innovative system with advanced fuel geometry and materials. The principal aim of the present research is to develop and qualify the control assembly (CA) pattern and corresponding CA implementation scheme for the 2400 MWth reference GFR design. The work has been carried out in three successive phases: (1) validation of the neutronics tools, (2) the CA pattern development and related static analysis, and (3) dynamic core behaviour studies for hypothetical CA driven transients. The deterministic code system ERANOS and its associated nuclear data libraries for fast reactors were developed and validated for sodium-cooled reactors. In order to validate ERANOS for GFR applications, a systematic reanalysis of the GFR-relevant integral data generated at PSI during the GCFR-PROTEUS experimental program of the 1970’s was undertaken. The reference PROTEUS test lattice has been analyzed with ERANOS-2.0 and its associated, adjusted nuclear data library ERALIB1. Benchmark calculations were performed with the Monte Carlo code MCNPX, allowing one to both check the deterministic results and to analyze the sensitivity to different modern data libraries. For the main reaction rate ratios, the new analysis of the GCFR

  9. Large superconducting wind turbine generators

    DEFF Research Database (Denmark)

    Abrahamsen, Asger Bech; Magnusson, Niklas; Jensen, Bogi Bech

    2012-01-01

    and the rotation speed is lowered in order to limit the tip speed of the blades. The ability of superconducting materials to carry high current densities with very small losses might facilitate a new class of generators operating with an air gap flux density considerably higher than conventional generators...... and thereby having a smaller size and weight [1, 2]. A 5 MW superconducting wind turbine generator forms the basics for the feasibility considerations, particularly for the YBCO and MgB2 superconductors entering the commercial market. Initial results indicate that a 5 MW generator with an active weight of 34...

  10. A large capacity turbine generator for nuclear power generation

    International Nuclear Information System (INIS)

    Maeda, Susumu; Miki, Takahiro; Suzuki, Kazuichi

    2000-01-01

    In future large capacity nuclear power plant, capacity of a generator to be applied will be 1800 MVA of the largest class in the world. In response to this, the Mitsubishi Electric Co., Ltd. began to carry out element technology verification of a four-pole large capacity turbine generator mainly using upgrading technique of large capacity, since 1994 fiscal year. And, aiming at reliability verification of the 1800 MVA class generator, a model generator with same cross-section as that of an actual one was manufactured, to carry out some verifications on its electrified tests, and so on. Every performance evaluation result of tests on the model generator were good, and high reliability to design and manufacturing technique of the 1800 MVA class generator could be verified. In future, on the base of these technologies, further upgrading of reliability on the large capacity turbine generator for nuclear power generation is intended to be carried out. (G.K.)

  11. A large electrically excited synchronous generator

    DEFF Research Database (Denmark)

    2014-01-01

    This invention relates to a large electrically excited synchronous generator (100), comprising a stator (101), and a rotor or rotor coreback (102) comprising an excitation coil (103) generating a magnetic field during use, wherein the rotor or rotor coreback (102) further comprises a plurality...... adjacent neighbouring poles. In this way, a large electrically excited synchronous generator (EESG) is provided that readily enables a relatively large number of poles, compared to a traditional EESG, since the excitation coil in this design provides MMF for all the poles, whereas in a traditional EESG...... each pole needs its own excitation coil, which limits the number of poles as each coil will take up too much space between the poles....

  12. Generation Expansion Planning Considering Integrating Large-scale Wind Generation

    DEFF Research Database (Denmark)

    Zhang, Chunyu; Ding, Yi; Østergaard, Jacob

    2013-01-01

    necessitated the inclusion of more innovative and sophisticated approaches in power system investment planning. A bi-level generation expansion planning approach considering large-scale wind generation was proposed in this paper. The first phase is investment decision, while the second phase is production...... optimization decision. A multi-objective PSO (MOPSO) algorithm was introduced to solve this optimization problem, which can accelerate the convergence and guarantee the diversity of Pareto-optimal front set as well. The feasibility and effectiveness of the proposed bi-level planning approach and the MOPSO...

  13. Future development of large superconducting generators

    International Nuclear Information System (INIS)

    Singh, S.K.; Mole, C.J.

    1989-01-01

    Large superconducting generators are being developed worldwide. The use of superconductors to reduce the electrical power dissipation in power equipment has been a technological possibility ever since the discovery of superconductivity, even though their use in power equipment remained an impractical dream for a long time. However, scientific and technological progress in superconductivity and cryogenics has brought this dream much closer to reality. Results obtained so far establish the technical feasibility of these machines. Analytical developments have been providing a sound basis for the design of superconducting machines and results of these design studies have shown improvements in power density of up to a factor of 10 higher than the power density for conventional machines. This paper describes the recently completed USA programs, the current foreign and USA programs, and then proposes a USA development program to maintain leadership in the field

  14. Development of the control assembly pattern and dynamic analysis of the generation IV large gas-cooled fast reactor (GFR)

    International Nuclear Information System (INIS)

    Girardin, G.

    2009-01-01

    Among the systems selected by the GIF, the Gas-cooled Fast Reactor (GFR) is a highly innovative system with advanced fuel geometry and materials. It is in the context of the large, 2400 MWth reference GFR design that the present doctoral research has been conducted, the principal aim having been to develop and qualify the control assembly (CA) pattern and corresponding CA implementation scheme for this system. The work has been carried out in three successive and complementary phases: (1) validation of the neutronics tools, (2) the CA pattern development and related static analysis, and (3) dynamic core behavior studies for hypothetical CA driven transients. During the first phase of the thesis, the reference PROTEUS test lattice from these experiments has been analyzed with ERANOS-2.0 and its associated, adjusted nuclear data library ERALIB1. Additionally, benchmark calculations were performed with the Monte Carlo code MCNPX, allowing one to both check the deterministic results and to analyze the sensitivity to different modern data libraries. It has been found that, for the main reaction rate ratios, the new analysis of the GCFR-PROTEUS reference lattice generally yields good agreement - within 1σ measurement uncertainty - with experimental values and with the Monte Carlo simulations. As shown by the analysis, the predictions were in somewhat better agreement in the case of the adjusted ERALIB1 library. The applicability of ERANOS-2.0/ERALIB1 as the reference neutronics tool for the GFR analysis could thus be demonstrated. Furthermore, neutronics aspects related to the novel features of the GFR, for which new experimental investigations are needed, were highlighted. In the second phase of the research, the CA pattern was developed for the GFR, based on iterative neutronics and thermal-hydraulics calculations, 2D and 3D neutronics models for the reactor core having first been set up using the reference ERANOS-2.0/ERALIB1 computational scheme. For the thermal

  15. Design evolution of large wind turbine generators

    Science.gov (United States)

    Spera, D. A.

    1979-01-01

    During the past five years, the goals of economy and reliability have led to a significant evolution in the basic design--both external and internal--of large wind turbine systems. To show the scope and nature of recent changes in wind turbine designs, development of three types are described: (1) system configuration developments; (2) computer code developments; and (3) blade technology developments.

  16. Structural Flexibility of Large Direct Drive Generators for Wind Turbines

    NARCIS (Netherlands)

    Shrestha, G.

    2013-01-01

    The trend in wind energy is towards large offshore wind farms. This trend has led to the demand for high reliability and large single unit wind turbines. Different energy conversion topologies such as multiple stage geared generators, single stage geared generators and gearless (direct drive)

  17. Prevention and investigations of core degradation in case of beyond design accidents of the 2400 MWTH gas-cooled fast reactor

    International Nuclear Information System (INIS)

    Bertrand, F.; Gatin, V.; Bentivoglio, F.; Gueneau, C.

    2011-01-01

    The present paper deals with studies carried out to assess the ability of the core of the Gas Fast Reactor (GFR) to withstand beyond design accidents. The work presented here is aimed at simulating the behaviour of this core by using analytical models whose input parameters are calculated with the CATHARE2 code. Among possible severe accident initiators, the Unprotected Loss Of Coolant Accident (ULOCA of 3 Inches diameter) is investigated in detail in the paper with CATHARE2. Additionally, a simplified pessimistic assessment of the effect of a postulated power excursion that could result from the failure of prevention provisions is presented. (author)

  18. Large scale renewable power generation advances in technologies for generation, transmission and storage

    CERN Document Server

    Hossain, Jahangir

    2014-01-01

    This book focuses on the issues of integrating large-scale renewable power generation into existing grids. It includes a new protection technique for renewable generators along with the inclusion of current status of smart grid.

  19. Vibration monitoring of large generator stator and-winding

    International Nuclear Information System (INIS)

    Duffeau, F.; Bernard, P.

    1999-01-01

    Large generators of French Nuclear Power plants are equipped with a standardised vibration monitoring system. The first aim of these new systems is to protect the machines by generating alarms in the control room when predefined vibration thresholds have been over-passed. Secondly, this specially designed instrumentation permits to create a National data base allowing to compare different generators of the same technology. Additionally, statistical methods have been developed in order to 'guess' vibration level at several locations of the stator end-windings, depending on the actual operating parameters of the generator, i.e. reactive and active power load. So this paper presents the general concept of the vibration monitoring of EDF large generator stators and deals with a new method to predict vibrations in different locations under control. (authors)

  20. Variability in large-scale wind power generation: Variability in large-scale wind power generation

    Energy Technology Data Exchange (ETDEWEB)

    Kiviluoma, Juha [VTT Technical Research Centre of Finland, Espoo Finland; Holttinen, Hannele [VTT Technical Research Centre of Finland, Espoo Finland; Weir, David [Energy Department, Norwegian Water Resources and Energy Directorate, Oslo Norway; Scharff, Richard [KTH Royal Institute of Technology, Electric Power Systems, Stockholm Sweden; Söder, Lennart [Royal Institute of Technology, Electric Power Systems, Stockholm Sweden; Menemenlis, Nickie [Institut de recherche Hydro-Québec, Montreal Canada; Cutululis, Nicolaos A. [DTU, Wind Energy, Roskilde Denmark; Danti Lopez, Irene [Electricity Research Centre, University College Dublin, Dublin Ireland; Lannoye, Eamonn [Electric Power Research Institute, Palo Alto California USA; Estanqueiro, Ana [LNEG, Laboratorio Nacional de Energia e Geologia, UESEO, Lisbon Spain; Gomez-Lazaro, Emilio [Renewable Energy Research Institute and DIEEAC/EDII-AB, Castilla-La Mancha University, Albacete Spain; Zhang, Qin [State Grid Corporation of China, Beijing China; Bai, Jianhua [State Grid Energy Research Institute Beijing, Beijing China; Wan, Yih-Huei [National Renewable Energy Laboratory, Transmission and Grid Integration Group, Golden Colorado USA; Milligan, Michael [National Renewable Energy Laboratory, Transmission and Grid Integration Group, Golden Colorado USA

    2015-10-25

    The paper demonstrates the characteristics of wind power variability and net load variability in multiple power systems based on real data from multiple years. Demonstrated characteristics include probability distribution for different ramp durations, seasonal and diurnal variability and low net load events. The comparison shows regions with low variability (Sweden, Spain and Germany), medium variability (Portugal, Ireland, Finland and Denmark) and regions with higher variability (Quebec, Bonneville Power Administration and Electric Reliability Council of Texas in North America; Gansu, Jilin and Liaoning in China; and Norway and offshore wind power in Denmark). For regions with low variability, the maximum 1 h wind ramps are below 10% of nominal capacity, and for regions with high variability, they may be close to 30%. Wind power variability is mainly explained by the extent of geographical spread, but also higher capacity factor causes higher variability. It was also shown how wind power ramps are autocorrelated and dependent on the operating output level. When wind power was concentrated in smaller area, there were outliers with high changes in wind output, which were not present in large areas with well-dispersed wind power.

  1. Holes generation in glass using large spot femtosecond laser pulses

    Science.gov (United States)

    Berg, Yuval; Kotler, Zvi; Shacham-Diamand, Yosi

    2018-03-01

    We demonstrate high-throughput, symmetrical, holes generation in fused silica glass using a large spot size, femtosecond IR-laser irradiation which modifies the glass properties and yields an enhanced chemical etching rate. The process relies on a balanced interplay between the nonlinear Kerr effect and multiphoton absorption in the glass which translates into symmetrical glass modification and increased etching rate. The use of a large laser spot size makes it possible to process thick glasses at high speeds over a large area. We have demonstrated such fabricated holes with an aspect ratio of 1:10 in a 1 mm thick glass samples.

  2. Experimental study on generation of large area uniform electron beam

    International Nuclear Information System (INIS)

    Tang Ying; Yi Aiping; Liu Jingru; Qian Hang; Huang Xin; Yu Li; Su Jiancang; Ding Zhenjie; Ding Yongzhong; Yu Jianguo

    2007-01-01

    In the experiment of gas laser pumped by electron beam, large area uniform electron beam is important to generate high efficiency laser output. The experimental study on generation of large area uniform electron beam with SPG-200 pulsed power generator is introduced. SPG-200 is an all-solid-state components pulsed power generator based on SOS, and its open voltage is more than 350 kV. The cathode have the area of 24 mm x 294 mm, and the anode-cathode(A-C)gap spacing is adjustable from 0 to 49 mm. The electron beam of cathode emission is transported to the laser chamber through the diode pressure foil, which sepa-rates the vacuum chamber from the laser chamber. Velvet and graphite cathodes are studied, each generates large area electron beam. The diode parameters are presented, and the uniformity of e-beam is diagnosed. The experimental results show that the diode voltage of the graphite cathode is 240-280 kV, and the diode current is 0.7-1.8 kA. The diode voltage of the velvet cathode is 200-250 kV, and the diode current is 1.5-1.7 kA. The uniformity of the velvet cathode emission is better than that of the graphite cathode. (authors)

  3. Generation of large-scale vortives in compressible helical turbulence

    International Nuclear Information System (INIS)

    Chkhetiani, O.G.; Gvaramadze, V.V.

    1989-01-01

    We consider generation of large-scale vortices in compressible self-gravitating turbulent medium. The closed equation describing evolution of the large-scale vortices in helical turbulence with finite correlation time is obtained. This equation has the form similar to the hydromagnetic dynamo equation, which allows us to call the vortx genertation effect the vortex dynamo. It is possible that principally the same mechanism is responsible both for amplification and maintenance of density waves and magnetic fields in gaseous disks of spiral galaxies. (author). 29 refs

  4. Bidding price analysis for competitive generators and large consumers

    International Nuclear Information System (INIS)

    Ping Wei; Luonan Chen; Hsiao Dong Chiang

    2005-01-01

    We present a new method to analyze the bidding price of each participant (power suppliers and large consumers) in a pay-as-bid market. The bidding price will be decomposed into a variety of components corresponding to five factors, such as the incremental values of the subject bidder's generation on the system operational costs, on the income or payment of other bidders, and on the binding tradable constraints, and the first-order approximation of the subjective participant's bidding price. From an economic viewpoint, each component provides useful information for participants to design the strategic planning. The advantages of the method include that the decomposition is well defined without assumptions and that each decomposition term has its own economical and/or engineering meaning. The proposed method is numerically verified through computer simulations on a three-bus example system and a modified IEEE 30-bus power system with both generator and large consumer bidding. (author)

  5. Large photovoltages generated by plant photosystem I crystals

    Energy Technology Data Exchange (ETDEWEB)

    Toporik, Hila; Carmeli, Chanoch; Nelson, Nathan [Department of Biochemistry and Molecular Biology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel); Carmeli, Itai [School of Chemistry, Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 (Israel); Volotsenko, Irina; Molotskii, Michel; Rosenwaks, Yossi [Department of Physical Electronics, Faculty of Engineering, Tel Aviv University, Tel Aviv 69978 (Israel)

    2012-06-12

    Micrometer-thick plant photosystem I crystals made of up to 1000 layers of serially arranged protein complexes generate unprecedented high photovoltages when placed on a conducting solid surface and measured using Kelvin probe force microscopy. The successive layers form serially photoinduced dipoles in the crystal that give rise to electric fields as large as 100 kV cm{sup -1}. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  6. Generating wind fluctuations for Large Eddy Simulation inflow boundary condition

    International Nuclear Information System (INIS)

    Bekele, S.A.; Hangan, H.

    2004-01-01

    Large Eddy Simulation (LES) studies of flows over bluff bodies immersed in a boundary layer wind environment require instantaneous wind characteristics. The influences of the wind environment on the building pressure distribution are a well-established fact in the experimental study of wind engineering. Measured wind data of full or model scale are available only at a limited number of points. A method of obtaining instantaneous wind data at all mesh points of the inlet boundary for LES computation is necessary. Herein previous and new wind inflow generation techniques are presented. The generated wind data is then applied to a LES computation of a channel flow. The characteristics of the generated wind fluctuations in comparison to the measured data and the properties of the flow field computed from these two wind data are discussed. (author)

  7. Five Large Generation Groups:Competing in Capital Operation

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Since the reform of electric power industry in 2002,the newly established five large generation groups have been persisting in the development strategy of "taking electricity as the core and extending to up-and-downstream businesses." Stringent measures were taken in capital operation and their potential has been shown through electric power assets acquiring,coal and financial resources investing,capital market financing as well as power utility restructuring.The five groups are playing more and more important roles in merger and acquisition (M&A) and capital markets.

  8. Resolution of torsional vibration issue for large turbine generators

    International Nuclear Information System (INIS)

    Evans, D.G.; Giesecke, H.D.; Willman, E.C.; Moffitt, S.P.

    1995-01-01

    The excitation of turbine generator torsional natural frequencies in the region near 120 Hz by electrical transients in the power system has resulted in blade failures for several large 1,800 rpm nuclear turbines. At Cleveland Electric's Perry Nuclear Power plant a combination of advanced measurement techniques and analyses were used to identify and resolve a potential torsional vibration problem without adverse impact on the plant availability. The Perry turbine generator consists of a high pressure turbine, three low pressure turbines with 43 inch last stage blades, and a 1,250 MWe four pole generator operating at 1,800 rpm. Torsional vibration measurements obtained from random vibration during operation were acquired just prior to the 1994 refueling outage. The measurements indicated that the 26th torsional mode of vibration was just under 120 Hz and within the range of frequencies for which the manufacturer recommends modifying the unit to shift the problem torsional natural frequency. Extensive analytical modeling was used to design a modification to shift the torsional natural frequencies away from 120 Hertz and the modification was implemented during the refueling outage without affecting outage critical path. An off-line ramp test and additional on-line monitoring performed at the conclusion of the outage confirmed that the on-line method provided accurate measurements of the torsional natural frequencies and demonstrated that, with the modification, the torsional natural frequencies were sufficiently removed from 120 Hertz to allow turbine generator operation. The modification, which involved brazing of the tie wires on all last stage blades, also significantly reduces the stress on the last stage blades that result from negative sequence currents, further increasing the operating margin of the turbine generator with respect to electrical transients and faults

  9. Large-scale generation of cell-derived nanovesicles

    Science.gov (United States)

    Jo, W.; Kim, J.; Yoon, J.; Jeong, D.; Cho, S.; Jeong, H.; Yoon, Y. J.; Kim, S. C.; Gho, Y. S.; Park, J.

    2014-09-01

    Exosomes are enclosed compartments that are released from cells and that can transport biological contents for the purpose of intercellular communications. Research into exosomes is hindered by their rarity. In this article, we introduce a device that uses centrifugal force and a filter with micro-sized pores to generate a large quantity of cell-derived nanovesicles. The device has a simple polycarbonate structure to hold the filter, and operates in a common centrifuge. Nanovesicles are similar in size and membrane structure to exosomes. Nanovesicles contain intracellular RNAs ranging from microRNA to mRNA, intracellular proteins, and plasma membrane proteins. The quantity of nanovesicles produced using the device is 250 times the quantity of naturally secreted exosomes. Also, the quantity of intracellular contents in nanovesicles is twice that in exosomes. Nanovesicles generated from murine embryonic stem cells can transfer RNAs to target cells. Therefore, this novel device and the nanovesicles that it generates are expected to be used in exosome-related research, and can be applied in various applications such as drug delivery and cell-based therapy.

  10. The Next-Generation Very Large Array: Technical Overview

    Science.gov (United States)

    McKinnon, Mark; Selina, Rob

    2018-01-01

    As part of its mandate as a national observatory, the NRAO is looking toward the long range future of radio astronomy and fostering the long term growth of the US astronomical community. NRAO has sponsored a series of science and technical community meetings to consider the science mission and design of a next-generation Very Large Array (ngVLA), building on the legacies of the Atacama Large Millimeter/submillimeter Array (ALMA) and the Very Large Array (VLA).The basic ngVLA design emerging from these discussions is an interferometric array with approximately ten times the sensitivity and ten times higher spatial resolution than the VLA and ALMA radio telescopes, optimized for operation in the wavelength range 0.3cm to 3cm. The ngVLA would open a new window on the Universe through ultra-sensitive imaging of thermal line and continuum emission down to milli-arcsecond resolution, as well as unprecedented broadband continuum polarimetric imaging of non-thermal processes. The specifications and concepts for major ngVLA system elements are rapidly converging.We will provide an overview of the current system design of the ngVLA. The concepts for major system elements such as the antenna, receiving electronics, and central signal processing will be presented. We will also describe the major development activities that are presently underway to advance the design.

  11. Large eddy simulation of the flow through a swirl generator

    Energy Technology Data Exchange (ETDEWEB)

    Conway, Stephen

    1998-12-01

    The advances made in computer technology over recent years have led to a great increase in the engineering problems that can be studied using CFD. The computation of flows over and through complex geometries at relatively high Reynolds numbers is becoming more common using the Large Eddy Simulation (LES) technique. Direct numerical simulations of such flows is still beyond the capacity of todays fastest supercomputers, requiring excessive computational times and memory. In addition, traditional Reynolds Averaged Navier Stokes (RANS) methods are known to have limited applicability in a wide range of engineering flow situations. In this thesis LES has been used to simulate the flow through a cascade of guidance vanes, more commonly known as a swirl generator, positioned at the inlet to a gas turbine combustion chamber. This flow case is of interest because of the complex flow phenomena which occur within the swirl generator, which include compressibility effects, different types of flow instabilities, transition, laminar and turbulent separation and near wall turbulence. It is also of interest because it fits very well into the range of engineering applications that can be studied using LES. Two computational grids with different resolutions and two subgrid scale stress models were used in the study. The effects of separation and transition are investigated. A vortex shedding frequency from the guidance vanes is determined which is seen to be dependent on the angle of incident air flow. Interaction between the movement of the separation region and the shedding frequency is also noted. Such vortex shedding phenomena can directly affect the quality of fuel and air mixing within the combustion chamber and can in some cases induce vibrations in the gas turbine structure. Comparisons between the results obtained using different grid resolutions with an implicit and a dynamic divergence (DDM) subgrid scale stress models are also made 32 refs, 35 figs, 2 tabs

  12. Fuzzy generation scheduling for a generation company (GenCo) with large scale wind farms

    International Nuclear Information System (INIS)

    Siahkali, H.; Vakilian, M.

    2010-01-01

    Wind power is a promising alternative in power generation because of its tremendous environmental and social benefits. Generation scheduling (GS) is more important in a power system integrating wind farms. Unlike conventional power generation sources, wind power generators supply intermittent power because of uncertainty in resource. This paper presents a fuzzy approach to the generation scheduling problem of a GenCo considering uncertainties in parameters or constraints such as load, reserve and available wind power generation. The modeling of constraints is an important issue in power system scheduling. A fuzzy optimization approach is an approach that can be used to obtain the generation scheduling under an uncertain environment. In this paper, a fuzzy optimization-based method is developed to solve power system GS problem with fuzzy objective and constraints. The crisp formulation of this GS problem is firstly defined and is rearranged by introduction of a membership function of some constraints and objective function. Then, this fuzzy optimization problem is converted to a crisp optimization and solved using GAMS software by mixed integer nonlinear programming. Employing the fuzzy optimization GS, it is expected that in practice a higher profit would be achieved in the operation and cost management of a real power system with large scale wind farms in different level of constraints' satisfaction. The proposed approach is applied to a sample system (including six conventional units and two wind farms) and the results are compared with the results of crisp solution. This approach is also applied to a larger test case to demonstrate the robustness of this fuzzy optimization method.

  13. In-plane fluidelastic instability analysis for large steam generators

    International Nuclear Information System (INIS)

    Mureithi, Njuki; Olala, Stephen; Hadji, Abdallah

    2015-01-01

    Fluidelastic instability remains the most important vibration excitation mechanism in nuclear steam generators (SGs). Design guidelines, aimed at eliminating the possibility of fluidelastic instability, have been developed over the past 40 years. The design guidelines, based on the Connors equation, depend on a large database on cross-flow fluidelastic instability i.e. instability in the direction transverse to the flow. Past experience had shown that for an axi-symmetrically flexible tube, instability generally occurred in the transverse direction, at least at first. Although often not explicitly stated, there has been an implicit assumption that the in-plane direction was either stable, or would only suffer instability at velocities significantly higher than the transverse direction. This explains why SGs are fitted with anti-vibrations bars (AVBs) to mitigate transverse (out-of-plane) vibrations with no equivalent consideration for potential in-plane instability. This 'oversight' recently came to a head when SG at the San-Onofre NPP suffered in-plane fluidelastic instability. The present paper addresses the question of in-plane fluidelastic instability in large SGs. A historical review is presented to explain why this potential problem was left unresolved (or ignored) over the past 40+ years, and why engineers got away with it - at least until recently. Following the review, some recent work on in-plane fluidelastic instability modeling, using the quasi-steady model is presented. It is shown that in-plane fluidelastic instability can be fully modelled using this approach. The model results are used to propose some changes to existing design guidelines to cover the case of in-plane fluidelastic instability. (author)

  14. A Review of Online Partial Discharge Measurement of Large Generators

    Directory of Open Access Journals (Sweden)

    Yuanlin Luo

    2017-10-01

    Full Text Available Online partial discharge (PD measurements have long been used as an effective means to assess the condition of the stator windings of large generators. An increase in the use of PD online measurement systems during the last decade is evident. Improvements in the detection capabilities are partly the reason for the increased popularity. Another reason has been the development of digital signal processing techniques. In addition, rapid progress is being made in automated single PD source classification. However, there are still some factors hindering wider application of the system, such as the complex PD mechanism and PD pulse propagation in stator windings, the presence of detrimental noise and disturbances on-site, and multiple PD sources occurring simultaneously. To avoid repetition of past work and to provide an overview for fresh researchers in this area, this paper presents a comprehensive survey of the state-of-the-art knowledge on PD mechanism, PD pulse propagation in stator windings, PD signal detection methods and signal processing techniques. Areas for further research are also presented.

  15. Large-scale multimodal transport modelling. Part 1: Demand generation

    CSIR Research Space (South Africa)

    Joubert, JW

    2013-07-01

    Full Text Available agents is generated using existing and available data. Using iterative proportional fitting (IPF), the population is generated for the Nelson Mandela Bay Metropolitan, and includes 24-hour activity chains for both primary activities such as home, work...

  16. The Southwest Configuration for the Next Generation Very Large Array

    Science.gov (United States)

    Irwin Kellermann, Kenneth; Carilli, Chris; Condon, James; Cotton, William; Murphy, Eric Joseph; Nyland, Kristina

    2018-01-01

    We discuss the planned array configuration for the Next Generation Very Large Array (ngVLA). The configuration, termed the "Southwest Array," consists of 214 antennas each 18 m in diameter, distributed over the Southwest United States and Northern Mexico. The antenna locations have been set applying rough real-world constraints, such as road, fiber, and power access. The antenna locations will be fixed, with roughly 50% of the antennas in a "core" of 2 km diameter, located at the site of the JVLA. Another 30% of the antennas will be distributed over the Plains of San Augustin to a diameter of 30 km, possibly along, or near, the current JVLA arms. The remaining 20% of the antennas will be distributed in a rough two-arm spiral pattern to the South and East, out to a maximum distance of 500 km, into Texas, Arizona, and Chihuahua. Years of experience with the VLA up to 50 GHz, plus intensive antenna testing up to 250 GHz for the ALMA prototype antennas, verify the VLA site as having very good observing conditions (opacity, phase stability), up to 115 GHz (ngVLA Memo No. 1). Using a suite of tools implemented in CASA, we have made extensive imaging simulations with this configuration. We find that good imaging performance can be obtained through appropriate weighting of the visibilities, for resolutions ranging from that of the core of the array (1" at 30 GHz), out to the longest baselines (10 mas at 30 GHz), with a loss of roughly a factor of two in sensitivity relative to natural weighting (ngVLA Memo No. 16). The off-set core, located on the northern edge of the long baseline configuration, provides excellent sensitivity even on the longest baselines. We are considering, in addition, a compact configuration of 16 close-packed 6 m antennas to obtain uv-coverage down to baselines ~ 10 m for imaging large scale structure, as well as a configuration including 9 stations distributed to continental scales.

  17. Electric Generators and their Control for Large Wind Turbines

    DEFF Research Database (Denmark)

    Boldea, Ion; Tutelea, Lucian; Rallabandi, Vandana

    2017-01-01

    induction generator, the cage rotor induction generator, and the synchronous generator with DC or permanent magnet excitation. The operating principle, performance, optimal design, and the modeling and control of the machine-side converter for each kind of generator are adressed and evaluated. In view......The electric generator and its power electronics interface for wind turbines (WTs) have evolved rapidly toward higher reliability and reduced cost of energy in the last 40 years. This chapter describes the up-to-date electric generators existing in the wind power industry, namely, the doubly fed...... of the fact that individual power rating of WTs has increased to around 10 MW, generator design and control technologies required to reach this power rating are discussed....

  18. Rated power factor and excitation system of large turbine generator

    International Nuclear Information System (INIS)

    Tokumitsu, Iwao; Watanabe, Takashi; Banjou, Minoru.

    1979-01-01

    As for the rated power factor of turbine generators for thermal power stations, 90% has been adopted since around 1960. On the other hand, power transmission system has entered 500 kV age, and 1,000 kV transmission is expected in the near future. As for the supply of reactive power from thermal and nuclear turbine generators, the necessity of supplying leading reactive power has rather increased. Now, the operating power factor of thermal and nuclear generators becomes 96 to 100% actually. As for the excess stability of turbine generators owing to the strengthening of transmission system and the adoption of super-high voltage, the demand of strict conditions can be dealt with by the adoption of super-fast response excitation system of thyristor shunt winding self exciting type. The adoption of the turbine generators with 90 to 95% power factor and the adoption of the thyristor shunt winding self exciting system were examined and evaluated. The rated power factor of generators, excitation system and economy of adopting these systems are explained. When the power factor of generators is increased from 0.9 to 0.95, about 6% of saving can be obtained in the installation cost. When the thyristor shunt winding self excitation is adopted, it is about 10% more economical than AC excitation. (Kako, I.)

  19. Pythoscape: A framework for generation of large protein similarity networks

    OpenAIRE

    Babbitt, Patricia; Barber, AE; Babbitt, PC

    2012-01-01

    Pythoscape is a framework implemented in Python for processing large protein similarity networks for visualization in other software packages. Protein similarity networks are graphical representations of sequence, structural and other similarities among pr

  20. Control of Permanent Magnet Synchronous Generator for large wind turbines

    DEFF Research Database (Denmark)

    Busca, Cristian; Stan, Ana-Irina; Stanciu, Tiberiu

    2010-01-01

    Direct Torque Control (DTC) and Field Oriented Control (FOC) are the most dominant control strategies used in generators for wind turbines. In this paper both control methods were implemented on a Permanent Magnet Synchronous Generator (PMSG). The variable speed wind turbine with full scale power...... converter topology was chosen for design. Parameters from a 2 MW wind turbine were used for system modeling. All the components of the wind turbine system (WTS), except the DC-link and the grid site converter were implemented in MATLAB/Simulink. The pitch controller was used to limit the output power...... produced by the turbine. DTC and FOC strategies, using SVM were used to control the generator rotor speed. The performance of the two control strategies were compared after different tests have been carried out....

  1. Development of the control assembly pattern and dynamic analysis of the generation IV large gas-cooled fast reactor (GFR); Developpement du design d'un assemblage de controle et analyse dynamique des reacteurs a neutrons rapides de quatrieme generation refroidis au gaz

    Energy Technology Data Exchange (ETDEWEB)

    Girardin, G.

    2009-07-09

    Among the systems selected by the GIF, the Gas-cooled Fast Reactor (GFR) is a highly innovative system with advanced fuel geometry and materials. It is in the context of the large, 2400 MWth reference GFR design that the present doctoral research has been conducted, the principal aim having been to develop and qualify the control assembly (CA) pattern and corresponding CA implementation scheme for this system. The work has been carried out in three successive and complementary phases: (1) validation of the neutronics tools, (2) the CA pattern development and related static analysis, and (3) dynamic core behavior studies for hypothetical CA driven transients. During the first phase of the thesis, the reference PROTEUS test lattice from these experiments has been analyzed with ERANOS-2.0 and its associated, adjusted nuclear data library ERALIB1. Additionally, benchmark calculations were performed with the Monte Carlo code MCNPX, allowing one to both check the deterministic results and to analyze the sensitivity to different modern data libraries. It has been found that, for the main reaction rate ratios, the new analysis of the GCFR-PROTEUS reference lattice generally yields good agreement - within 1{sigma} measurement uncertainty - with experimental values and with the Monte Carlo simulations. As shown by the analysis, the predictions were in somewhat better agreement in the case of the adjusted ERALIB1 library. The applicability of ERANOS-2.0/ERALIB1 as the reference neutronics tool for the GFR analysis could thus be demonstrated. Furthermore, neutronics aspects related to the novel features of the GFR, for which new experimental investigations are needed, were highlighted. In the second phase of the research, the CA pattern was developed for the GFR, based on iterative neutronics and thermal-hydraulics calculations, 2D and 3D neutronics models for the reactor core having first been set up using the reference ERANOS-2.0/ERALIB1 computational scheme. For the thermal

  2. Optimal bidding strategies for competitive generators and large consumers

    International Nuclear Information System (INIS)

    Fushuan Wen; David, A.K.

    2001-01-01

    There exists the potential for gaming such as strategic bidding by participants (power suppliers and large consumers) in a deregulated power market, which is more an oligopoly than a laissez-faire market. Each participant can increase his or her own profit through strategic bidding but this has a negative effect on maximising social welfare. A method to build bidding strategies for both power suppliers and large consumers in a poolco-type electricity market is presented in this paper. It is assumed that each supplier/large consumer bids a linear supply/demand function, and the system is dispatched to maximise social welfare. Each supplier/large consumer chooses the coefficients in the linear supply/demand function to maximise benefits, subject to expectations about how rival participants will bid. The problem is formulated as a stochastic optimisation problem, and solved by a Monte Carlo approach. A numerical example with six suppliers and two large consumers serves to illustrate the essential features of the method. (author)

  3. Competition between coal and gas for large scale power generation

    International Nuclear Information System (INIS)

    Howieson, B.

    1997-01-01

    The relative competitiveness of coal- and gas-fired generation will be affected by distinctive country and market factors as well as site specific considerations, regarding such factors as environment, market structure and economics (such as fuel and plant costs). National and international politics have an impact on all three factors and any decision on the development of generation plant must take into account both current and future political climates. An analysis suggests that, at the present time, upgrading existing coal stations is attractive compared with new combined cycle gas turbines (CCGTs). However, this conclusion is highly dependent on the site specific nature of existing plant and the anticipated future environmental regime. Increased environmental pressure, particularly in the area of CO 2 emissions, would result in CCGTs being the first choice plant option. (R.P.)

  4. Large sodium water reaction calculations in a LMFBR steam generator

    International Nuclear Information System (INIS)

    Finck, P.; Lepareux, M.; Schwab, B.; Blanchet, Y.

    1986-05-01

    The French approach to the analysis of large and violent sodium water reactions is presented. The basis for choosing the Design Basis Accident is discussed. An energetical analysis of the physical phenomena involved stresses the specific needs for computing tools. The feature of these tools are then described, and a validation test is presented. Finally, industrial applications are described. 8 refs

  5. Some Fluid Dynamic Effects in Large-Scale MHD Generators

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, J. C.R. [University of Warwick, Coventry (United Kingdom)

    1966-10-15

    At the present time we are unable to carry out a complete analysis of the fluid dynamics and electrodynamics of an MHD generator. However, various aspects of the behaviour of an MHD generator may be examined by the use of simplified models, for example: (1) one-dimensional gas dynamics (Louis et al. 1964); (2) the current distribution can be found if the velocity is assumed constant across the duct (Witalis, 1965); (3) the skin friction and heat transfer to the walls can be calculated by boundary layer analysis if the flow is assumed to be laminar (Kerrebrock, 1961), and (4) a complete description of the velocity and current distribution across the duct can be given if the flow is assumed to be uniform, laminar, incompressible and not varying in the flow direction (Hunt and Stewartson, 1965). Taken together, these and other models will enable us to describe most of the effects in an MHD generator. In this paper another simplification is considered in which the electromagnetic forces are assumed to be much larger than the inertial forces. The ratio of these two forces is measured by the parameter, S = aB{sup 2}{sub 0}d/pU, where o is the conductivity, B{sub 0} the magnetic field, d the width of the duct, p the density and U the mean velocity. Thus S >> 1. We also assume that the magnetic Reynolds number is very much less than one. In the largest experimental generators now being built S {approx} 2 . Thus, though the results of this model are not immediately applicable, they should indicate the effects of increasing the magnetic field strength and the size of MHD generators. When S >> 1, one can can consider the duct to be divided into 2 regions: (1) a core region where electromagnetic forces are balanced by the pressure gradient and where inertial as well as viscous forces are negligible, and (2) boundary layers on the walls where again inertial forces are negligible but where the viscous, electromagnetic and pressure forces are of the same order. We show how it is

  6. Design Methodology of Large-scale Thermoelectric Generation

    DEFF Research Database (Denmark)

    Chen, Min; Gao, Junling; Zhu, Junpeng

    2011-01-01

    A thermoelectric generation system (TEGS) consists of not only thermoelectric modules (TEMs), but also the external load circuitry and the fluidic heat sources. In this paper, a system-level model is proposed in the SPICE-compatible environment to seamlessly integrate the complete fluid-thermal-e......A thermoelectric generation system (TEGS) consists of not only thermoelectric modules (TEMs), but also the external load circuitry and the fluidic heat sources. In this paper, a system-level model is proposed in the SPICE-compatible environment to seamlessly integrate the complete fluid......-thermal-electric-circuit multiphysics behaviors. Firstly, a quasi one-dimension numerical model for the thermal fluids and their non-uniform temperature distribution as the boundary condition for TEMs is implemented in SPICE using electrothermal analogy. Secondly, the electric field calculation of the previously proposed device......-level SPICE model is upgraded to reflect the resistive behaviors of thermoelements, so that the electric connections among spatially distributed TEMs and the load circuitry can be freely combined in the simulation. Thirdly, a hierarchical and TEM-object oriented strategy is developed to make the system...

  7. Pythoscape: a framework for generation of large protein similarity networks.

    Science.gov (United States)

    Barber, Alan E; Babbitt, Patricia C

    2012-11-01

    Pythoscape is a framework implemented in Python for processing large protein similarity networks for visualization in other software packages. Protein similarity networks are graphical representations of sequence, structural and other similarities among proteins for which pairwise all-by-all similarity connections have been calculated. Mapping of biological and other information to network nodes or edges enables hypothesis creation about sequence-structure-function relationships across sets of related proteins. Pythoscape provides several options to calculate pairwise similarities for input sequences or structures, applies filters to network edges and defines sets of similar nodes and their associated data as single nodes (termed representative nodes) for compression of network information and output data or formatted files for visualization.

  8. Thermal power generation projects ``Large Scale Solar Heating``; EU-Thermie-Projekte ``Large Scale Solar Heating``

    Energy Technology Data Exchange (ETDEWEB)

    Kuebler, R.; Fisch, M.N. [Steinbeis-Transferzentrum Energie-, Gebaeude- und Solartechnik, Stuttgart (Germany)

    1998-12-31

    The aim of this project is the preparation of the ``Large-Scale Solar Heating`` programme for an Europe-wide development of subject technology. The following demonstration programme was judged well by the experts but was not immediately (1996) accepted for financial subsidies. In November 1997 the EU-commission provided 1,5 million ECU which allowed the realisation of an updated project proposal. By mid 1997 a small project was approved, that had been requested under the lead of Chalmes Industriteteknik (CIT) in Sweden and is mainly carried out for the transfer of technology. (orig.) [Deutsch] Ziel dieses Vorhabens ist die Vorbereitung eines Schwerpunktprogramms `Large Scale Solar Heating`, mit dem die Technologie europaweit weiterentwickelt werden sollte. Das daraus entwickelte Demonstrationsprogramm wurde von den Gutachtern positiv bewertet, konnte jedoch nicht auf Anhieb (1996) in die Foerderung aufgenommen werden. Im November 1997 wurden von der EU-Kommission dann kurzfristig noch 1,5 Mio ECU an Foerderung bewilligt, mit denen ein aktualisierter Projektvorschlag realisiert werden kann. Bereits Mitte 1997 wurde ein kleineres Vorhaben bewilligt, das unter Federfuehrung von Chalmers Industriteknik (CIT) in Schweden beantragt worden war und das vor allem dem Technologietransfer dient. (orig.)

  9. SNR-steam generator design with respect to large sodium water reactions

    International Nuclear Information System (INIS)

    Jong, J.J. de; Kellner, A.; Florie, C.J.L.

    1984-01-01

    This paper deals with the experiences gained during the licensing procedure for the steam generators for the SNR 300 LMFBR regarding large sodium-water reactions. A description is given of the different calculations executed to investigate the effects of large leaks on the 85 MW helical coiled and straight tube steam generators. The investigations on the helical coiled steam generators are divided in the formulations of fluid behaviour, dynamic force calculations, dynamic response calculation and finally stress analyses. Several results are shown. The investigations on the straight tube steam generators are performed using models describing fluid-structure interaction, coupled with stress analyses. Several results are presented. A description is given of the problems and necessary construction changes during the licensing process. Advises are given for future analyses and design concepts for second generation commercial size LMFBR steam generators with respect to large leaks; based on the experience, gained with SNR 300, and using some new calculations for SNR 2. (author)

  10. The Feasibility of Small Hydro-Electric Generation in a Large Urban Area

    OpenAIRE

    Benson Y. Zhang; Adam Taylor

    2012-01-01

    The possibilities of generating electric power from relatively small hydro-electric sources in a large urban area is investigated. Two different aspects of hydro-electric sources have been studied: storm/waste water pipes in large multi-tenanted residential buildings and urban storm water discharge area (CSI area). The potential to generate from these sources has been investigated using a micro-turbine. The potential electric power which could be extracted from the sources was estimated using...

  11. Preliminary Feasibility Study on Application of Very Large Scale-Photovoltaic Power Generation in China

    Institute of Scientific and Technical Information of China (English)

    Hu Xuehao; Zhou Xiaoxin; Bai Xiaomin; Zhang Wentao

    2005-01-01

    Solar energy photovoltaic power generation is hopeful to be applied in a large amount and possesses a certain proportion in the structure of energy in the future. In this paper, based on the forecasting of electric load demand and energy structure of power generation in the middle of 21century, the pictures of VLS-PV power generation is composed, the operation characteristic of VLS-PV power generation and the adaptability of electric power grid for it is analyzed, the ways for transmitting large amount of PV power and the economic and technical bottlenecks for applying VLS-PV power generation are discussed. Finally, the steps and suggestions for developing VLS-PV power generation and its electric power system in China are proposed.

  12. Modelling of electricity generation of large interconnected power systems: How can a CO2 tax influence the European generation mix

    International Nuclear Information System (INIS)

    Voorspools, Kris R.; D'haeseleer, William D.

    2006-01-01

    This paper discusses a methodology for detailed modelling of electricity generation of large interconnected power systems in a liberalised market. The resulting model, called E-Simulate, respects the technological restrictions and boundary conditions inherent to power generation and simulates the power generation and cross border trade on an hourly basis and on a power plant level. Nevertheless, E-Simulate is sufficiently flexible, transparent and fast. It is a valid, objective and useful tool in the simulation of the impact of power generation topics in the context of liberalised markets and GHG emission reduction. As a comprehensive example of the use and the strength of E-Simulate, we study the effect of a CO 2 tax on power generation and electricity trade in and between eight interconnected European zones: The Netherlands, Belgium/Luxemburg, France, Germany, Spain, Portugal, Switzerland and Italy. A CO 2 tax of 10 Euro /ton CO 2 causes an overall CO 2 emission reduction of about 6%. We notice an overall increase in gas fired generation and a corresponding reduction of coal and lignite fired generation on a trans-national level. In some zones (The Netherlands, Belgium/Luxemburg and Italy), the emissions will rise. In others (France, Germany and Spain), emissions will decrease. This is a result of the CO 2 tax that not only causes a shift towards fuels with lower carbon content but also, and correspondingly, leads to a redistribution of cross border trade

  13. Cost reduction for large turbine generator Pedestal in high seismic zone

    International Nuclear Information System (INIS)

    Sawhney, P.S.; Irani, P.; Pusheck, B.N.

    1985-01-01

    Turbine Generator Pedestals have generally been designed using reinforced concrete. For present day large turbine generators (1100 MWe class and above) with tall (about 80 feet) pedestals, the amount of reinforcing steel becomes quite large, especially for plants in high seismic zones. With the prime objective of cost reduction, an approach using steel/concrete composite design has been studied for a large BWR Turbine Generator pedestal with 0.3g peak ground acceleration. Large prefabricated steel modules were adopted for composite design and simplified construction. Design was based on the ACI and AISC codes. Costs and schedules were developed and compared with those for a conventionally designed reinforced concrete pedestal. Composite design was found to give considerable cost and schedule advantage over the conventional reinforced concrete design

  14. Generation of large-scale PV scenarios using aggregated power curves

    DEFF Research Database (Denmark)

    Nuño Martinez, Edgar; Cutululis, Nicolaos Antonio

    2017-01-01

    The contribution of solar photovoltaic (PV) power to the generation is becoming more relevant in modern power system. Therefore, there is a need to model the variability large-scale PV generation accurately. This paper presents a novel methodology to generate regional PV scenarios based...... on aggregated power curves rather than traditional physical PV conversion models. Our approach is based on hourly mesoscale reanalysis irradiation data and power measurements and do not require additional variables such as ambient temperature or wind speed. It was used to simulate the PV generation...... on the German system between 2012 and 2015 showing high levels of correlation with actual measurements (93.02–97.60%) and small deviations from the expected capacity factors (0.02–1.80%). Therefore, we are confident about the ability of the proposed model to accurately generate realistic large-scale PV...

  15. Recent developments in large-scale ozone generation with dielectric barrier discharges

    Science.gov (United States)

    Lopez, Jose L.

    2014-10-01

    Large-scale ozone generation for industrial applications has been entirely based on the creation of microplasmas or microdischarges created using dielectric barrier discharge (DBD) reactors. Although versions of DBD generated ozone have been in continuous use for over a hundred years especially in water treatment, recent changes in environmental awareness and sustainability have lead to a surge of ozone generating facilities throughout the world. As a result of this enhanced global usage of this environmental cleaning application various new discoveries have emerged in the science and technology of ozone generation. This presentation will describe some of the most recent breakthrough developments in large-scale ozone generation while further addressing some of the current scientific and engineering challenges of this technology.

  16. Large-scale DNA Barcode Library Generation for Biomolecule Identification in High-throughput Screens.

    Science.gov (United States)

    Lyons, Eli; Sheridan, Paul; Tremmel, Georg; Miyano, Satoru; Sugano, Sumio

    2017-10-24

    High-throughput screens allow for the identification of specific biomolecules with characteristics of interest. In barcoded screens, DNA barcodes are linked to target biomolecules in a manner allowing for the target molecules making up a library to be identified by sequencing the DNA barcodes using Next Generation Sequencing. To be useful in experimental settings, the DNA barcodes in a library must satisfy certain constraints related to GC content, homopolymer length, Hamming distance, and blacklisted subsequences. Here we report a novel framework to quickly generate large-scale libraries of DNA barcodes for use in high-throughput screens. We show that our framework dramatically reduces the computation time required to generate large-scale DNA barcode libraries, compared with a naїve approach to DNA barcode library generation. As a proof of concept, we demonstrate that our framework is able to generate a library consisting of one million DNA barcodes for use in a fragment antibody phage display screening experiment. We also report generating a general purpose one billion DNA barcode library, the largest such library yet reported in literature. Our results demonstrate the value of our novel large-scale DNA barcode library generation framework for use in high-throughput screening applications.

  17. A cooling concept for improved field winding performance in large superconducting ac generators

    International Nuclear Information System (INIS)

    Laskaris, T.E.

    1977-01-01

    An analytical study of a flow circuit for large superconducting generator rotors is presented. The flow circuit provides regulation of the level of liquid in the rotor externally by adjusting the helium supply pressure. It also protects the vapour cooled structural members of the rotor from overcooling during transient periods of operation. Furthermore, it is capable of reducing the winding temperature below 4.2 K thereby enhancing the superconductor's performance. For example, a large generator rotor with NbTi superconducting field winding experiences approximately a 50% increase in its critical current density compared to that at 4.2 K. (author)

  18. A Statistical Model for Hourly Large-Scale Wind and Photovoltaic Generation in New Locations

    DEFF Research Database (Denmark)

    Ekstrom, Jussi; Koivisto, Matti Juhani; Mellin, Ilkka

    2017-01-01

    The analysis of large-scale wind and photovoltaic (PV) energy generation is of vital importance in power systems where their penetration is high. This paper presents a modular methodology to assess the power generation and volatility of a system consisting of both PV plants (PVPs) and wind power...... of new PVPs and WPPs in system planning. The model is verified against hourly measured wind speed and solar irradiance data from Finland. A case study assessing the impact of the geographical distribution of the PVPs and WPPs on aggregate power generation and its variability is presented....

  19. Smart Energy Cryo-refrigerator Technology for the next generation Very Large Array

    Science.gov (United States)

    Spagna, Stefano

    2018-01-01

    We describe a “smart energy” cryocooler technology architecture for the next generation Very Large Array that makes use of multiple variable frequency cold heads driven from a single variable speed air cooled compressor. Preliminary experiments indicate that the compressor variable flow control, advanced diagnostics, and the cryo-refrigerator low vibration, provide a unique energy efficient capability for the very large number of antennas that will be employed in this array.

  20. The large-scale integration of wind generation: Impacts on price, reliability and dispatchable conventional suppliers

    International Nuclear Information System (INIS)

    MacCormack, John; Hollis, Aidan; Zareipour, Hamidreza; Rosehart, William

    2010-01-01

    This work examines the effects of large-scale integration of wind powered electricity generation in a deregulated energy-only market on loads (in terms of electricity prices and supply reliability) and dispatchable conventional power suppliers. Hourly models of wind generation time series, load and resultant residual demand are created. From these a non-chronological residual demand duration curve is developed that is combined with a probabilistic model of dispatchable conventional generator availability, a model of an energy-only market with a price cap, and a model of generator costs and dispatch behavior. A number of simulations are performed to evaluate the effect on electricity prices, overall reliability of supply, the ability of a dominant supplier acting strategically to profitably withhold supplies, and the fixed cost recovery of dispatchable conventional power suppliers at different levels of wind generation penetration. Medium and long term responses of the market and/or regulator in the long term are discussed.

  1. Large-Scale Combined Heat and Power (CHP) Generation at Loviisa Nuclear Power Plant Unit 3

    International Nuclear Information System (INIS)

    Bergroth, N.

    2010-01-01

    Fortum has applied for a Decision in Principle concerning the construction of a new nuclear power plant unit (Loviisa 3) ranging from 2800-4600 MWth at its site located at the southern coast of Finland. An attractive alternative investigated is a co-generation plant designed for large-scale district heat generation for the Helsinki metropolitan area that is located approximately 75 km west of the site. The starting point is that the district heat generation capacity of 3 unit would be around 1 000 MWth.The possibility of generating district heat for the metropolitan area by Loviisa's two existing nuclear power plant units was investigated back in the 1980s, but it proved unpractical at the time. With the growing concern of the climate change and the subsequent requirements on heat and power generation, the idea is much more attractive today, when recognising its potential to decrease Finland's carbon dioxide emissions significantly. Currently the district heat generation in metropolitan area is based on coal and natural gas, producing some five to seven million tonnes of carbon dioxide emissions annually. Large-scale combined heat and power (CHP) generation at the 3 unit could cut this figure by up to four million tonnes. This would decrease carbon dioxide emissions by as much as six percent. In addition, large-scale CHP generation would increase the overall efficiency of the new unit significantly and hence, reduce the environmental impact on the local marine environment by cutting heat discharges into the Gulf of Nuclear energy has been used for district heating in several countries both in dedicated nuclear heating plants and in CHP generation plants. However, the heat generation capacity is usually rather limited, maximum being around 250 MWth per unit. Set against this, the 3 CHP concept is much more ambitious, not only because of the much larger heat generation output envisaged, but also because the district heating water would have to be transported over a

  2. System Dynamics Simulation of Large-Scale Generation System for Designing Wind Power Policy in China

    Directory of Open Access Journals (Sweden)

    Linna Hou

    2015-01-01

    Full Text Available This paper focuses on the impacts of renewable energy policy on a large-scale power generation system, including thermal power, hydropower, and wind power generation. As one of the most important clean energy, wind energy has been rapidly developed in the world. But in recent years there is a serious waste of wind power equipment and investment in China leading to many problems in the industry from wind power planning to its integration. One way overcoming the difficulty is to analyze the influence of wind power policy on a generation system. This paper builds a system dynamics (SD model of energy generation to simulate the results of wind energy generation policies based on a complex system. And scenario analysis method is used to compare the effectiveness and efficiency of these policies. The case study shows that the combinations of lower portfolio goal and higher benchmark price and those of higher portfolio goal and lower benchmark price have large differences in both effectiveness and efficiency. On the other hand, the combinations of uniformly lower or higher portfolio goal and benchmark price have similar efficiency, but different effectiveness. Finally, an optimal policy combination can be chosen on the basis of policy analysis in the large-scale power system.

  3. Power Generation from a Radiative Thermal Source Using a Large-Area Infrared Rectenna

    Science.gov (United States)

    Shank, Joshua; Kadlec, Emil A.; Jarecki, Robert L.; Starbuck, Andrew; Howell, Stephen; Peters, David W.; Davids, Paul S.

    2018-05-01

    Electrical power generation from a moderate-temperature thermal source by means of direct conversion of infrared radiation is important and highly desirable for energy harvesting from waste heat and micropower applications. Here, we demonstrate direct rectified power generation from an unbiased large-area nanoantenna-coupled tunnel diode rectifier called a rectenna. Using a vacuum radiometric measurement technique with irradiation from a temperature-stabilized thermal source, a generated power density of 8 nW /cm2 is observed at a source temperature of 450 °C for the unbiased rectenna across an optimized load resistance. The optimized load resistance for the peak power generation for each temperature coincides with the tunnel diode resistance at zero bias and corresponds to the impedance matching condition for a rectifying antenna. Current-voltage measurements of a thermally illuminated large-area rectenna show current zero crossing shifts into the second quadrant indicating rectification. Photon-assisted tunneling in the unbiased rectenna is modeled as the mechanism for the large short-circuit photocurrents observed where the photon energy serves as an effective bias across the tunnel junction. The measured current and voltage across the load resistor as a function of the thermal source temperature represents direct current electrical power generation.

  4. Teaching the Assessment of Normality Using Large Easily-Generated Real Data Sets

    Science.gov (United States)

    Kulp, Christopher W.; Sprechini, Gene D.

    2016-01-01

    A classroom activity is presented, which can be used in teaching students statistics with an easily generated, large, real world data set. The activity consists of analyzing a video recording of an object. The colour data of the recorded object can then be used as a data set to explore variation in the data using graphs including histograms,…

  5. Power Electronic Drives, Controls, and Electric Generators for Large Wind Turbines - An Overview

    DEFF Research Database (Denmark)

    Ma, Ke; Tutelea, L.; Boldea, Ion

    2015-01-01

    and exceed a power rating of 10 MW are discussed. The role of power electronics for improving the operation of wind turbines and ensuring compliance with power grid codes is analyzed with a view at producing fully controllable generation units suitable for tight integration into the power grid and large...

  6. Large deviation estimates for a Non-Markovian Lévy generator of big order

    International Nuclear Information System (INIS)

    Léandre, Rémi

    2015-01-01

    We give large deviation estimates for a non-markovian convolution semi-group with a non-local generator of Lévy type of big order and with the standard normalisation of semi-classical analysis. No stochastic process is associated to this semi-group. (paper)

  7. Transition to a new generation of large natural-draught cooling towers

    International Nuclear Information System (INIS)

    Biller, H.; Boslau, C.; Heyde, K.; Kockelke, W.

    1985-01-01

    A concept of a new generation of natural-draught cooling towers for large nuclear power plant units is presented considering optimization and calculation methods, safety philosophy, dimension criteria, constructional measures, building materials, construction surveying, climbing formwork, and climbing cranes. The first installation will be available by 1990, with a unit 250 m in diameter by 150 m high

  8. Generating mock data sets for large-scale Lyman-α forest correlation measurements

    International Nuclear Information System (INIS)

    Font-Ribera, Andreu; McDonald, Patrick; Miralda-Escudé, Jordi

    2012-01-01

    Massive spectroscopic surveys of high-redshift quasars yield large numbers of correlated Lyα absorption spectra that can be used to measure large-scale structure. Simulations of these surveys are required to accurately interpret the measurements of correlations and correct for systematic errors. An efficient method to generate mock realizations of Lyα forest surveys is presented which generates a field over the lines of sight to the survey sources only, instead of having to generate it over the entire three-dimensional volume of the survey. The method can be calibrated to reproduce the power spectrum and one-point distribution function of the transmitted flux fraction, as well as the redshift evolution of these quantities, and is easily used for modeling any survey systematic effects. We present an example of how these mock surveys are applied to predict the measurement errors in a survey with similar parameters as the BOSS quasar survey in SDSS-III

  9. Generating mock data sets for large-scale Lyman-α forest correlation measurements

    Energy Technology Data Exchange (ETDEWEB)

    Font-Ribera, Andreu [Institut de Ciències de l' Espai (CSIC-IEEC), Campus UAB, Fac. Ciències, torre C5 parell 2, Bellaterra, Catalonia (Spain); McDonald, Patrick [Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 (United States); Miralda-Escudé, Jordi, E-mail: font@ieec.uab.es, E-mail: pvmcdonald@lbl.gov, E-mail: miralda@icc.ub.edu [Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia (Spain)

    2012-01-01

    Massive spectroscopic surveys of high-redshift quasars yield large numbers of correlated Lyα absorption spectra that can be used to measure large-scale structure. Simulations of these surveys are required to accurately interpret the measurements of correlations and correct for systematic errors. An efficient method to generate mock realizations of Lyα forest surveys is presented which generates a field over the lines of sight to the survey sources only, instead of having to generate it over the entire three-dimensional volume of the survey. The method can be calibrated to reproduce the power spectrum and one-point distribution function of the transmitted flux fraction, as well as the redshift evolution of these quantities, and is easily used for modeling any survey systematic effects. We present an example of how these mock surveys are applied to predict the measurement errors in a survey with similar parameters as the BOSS quasar survey in SDSS-III.

  10. The viability of balancing wind generation with large scale energy storage

    International Nuclear Information System (INIS)

    Nyamdash, Batsaikhan; Denny, Eleanor; O'Malley, Mark

    2010-01-01

    This paper studies the impact of combining wind generation and dedicated large scale energy storage on the conventional thermal plant mix and the CO 2 emissions of a power system. Different strategies are proposed here in order to explore the best operational strategy for the wind and storage system in terms of its effect on the net load. Furthermore, the economic viability of combining wind and large scale storage is studied. The empirical application, using data for the Irish power system, shows that combined wind and storage reduces the participation of mid-merit plants and increases the participation of base-load plants. Moreover, storage negates some of the CO 2 emissions reduction of the wind generation. It was also found that the wind and storage output can significantly reduce the variability of the net load under certain operational strategies and the optimal strategy depends on the installed wind capacity. However, in the absence of any supporting mechanism none of the storage devices were economically viable when they were combined with the wind generation on the Irish power system. - Research Highlights: → Energy storage would displace the peaking and mid-merit plants generations by the base-load plants generations. Energy storage may negate the CO 2 emissions reduction that is due to the increased wind generations. →Energy storage reduces the variation of the net load. →Under certain market conditions, merchant type energy storage is not viable.

  11. Two methods for estimating limits to large-scale wind power generation.

    Science.gov (United States)

    Miller, Lee M; Brunsell, Nathaniel A; Mechem, David B; Gans, Fabian; Monaghan, Andrew J; Vautard, Robert; Keith, David W; Kleidon, Axel

    2015-09-08

    Wind turbines remove kinetic energy from the atmospheric flow, which reduces wind speeds and limits generation rates of large wind farms. These interactions can be approximated using a vertical kinetic energy (VKE) flux method, which predicts that the maximum power generation potential is 26% of the instantaneous downward transport of kinetic energy using the preturbine climatology. We compare the energy flux method to the Weather Research and Forecasting (WRF) regional atmospheric model equipped with a wind turbine parameterization over a 10(5) km2 region in the central United States. The WRF simulations yield a maximum generation of 1.1 We⋅m(-2), whereas the VKE method predicts the time series while underestimating the maximum generation rate by about 50%. Because VKE derives the generation limit from the preturbine climatology, potential changes in the vertical kinetic energy flux from the free atmosphere are not considered. Such changes are important at night when WRF estimates are about twice the VKE value because wind turbines interact with the decoupled nocturnal low-level jet in this region. Daytime estimates agree better to 20% because the wind turbines induce comparatively small changes to the downward kinetic energy flux. This combination of downward transport limits and wind speed reductions explains why large-scale wind power generation in windy regions is limited to about 1 We⋅m(-2), with VKE capturing this combination in a comparatively simple way.

  12. A simple biosynthetic pathway for large product generation from small substrate amounts

    Science.gov (United States)

    Djordjevic, Marko; Djordjevic, Magdalena

    2012-10-01

    A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways.

  13. A simple biosynthetic pathway for large product generation from small substrate amounts

    Energy Technology Data Exchange (ETDEWEB)

    Djordjevic, Marko [Institute of Physiology and Biochemistry, Faculty of Biology, University of Belgrade (Serbia); Djordjevic, Magdalena [Institute of Physics Belgrade, University of Belgrade (Serbia)

    2012-10-01

    A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways. (paper)

  14. A simple biosynthetic pathway for large product generation from small substrate amounts

    International Nuclear Information System (INIS)

    Djordjevic, Marko; Djordjevic, Magdalena

    2012-01-01

    A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways. (paper)

  15. Search for leptoquarks with large couplings to third generation quarks with CMS

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Leptoquarks with masses at the TeV scale have been suggested as possible solutions to flavour anomalies reported in the B meson sector. Phenomenological analyses suggest that large leptoquark couplings to third generation quarks and leptons, as well as the existence of more than one leptoquark state and additional gauge boson resonances, could explain these anomalies. Owing to the large dataset collected during Run 2 of the LHC at sqrt(s) = 13 TeV, these states can be probed in high transverse-momentum final states. We present a summary of searches for signatures from the pair production of leptoquarks and gauge boson resonances with large couplings to third generation quarks and leptons based on data taken in proton-proton collisions with the CMS detector.

  16. Processing large sensor data sets for safeguards : the knowledge generation system.

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Maikel A.; Smartt, Heidi Anne; Matthews, Robert F.

    2012-04-01

    Modern nuclear facilities, such as reprocessing plants, present inspectors with significant challenges due in part to the sheer amount of equipment that must be safeguarded. The Sandia-developed and patented Knowledge Generation system was designed to automatically analyze large amounts of safeguards data to identify anomalous events of interest by comparing sensor readings with those expected from a process of interest and operator declarations. This paper describes a demonstration of the Knowledge Generation system using simulated accountability tank sensor data to represent part of a reprocessing plant. The demonstration indicated that Knowledge Generation has the potential to address several problems critical to the future of safeguards. It could be extended to facilitate remote inspections and trigger random inspections. Knowledge Generation could analyze data to establish trust hierarchies, to facilitate safeguards use of operator-owned sensors.

  17. Large-leak sodium-water reaction analysis for steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Sakano, K; Shindo, Y; Hori, M

    1975-07-01

    The guillotine rupture of 4 tubes is assumed as a design basis regarding the large-leak sodium-water reaction in the system of the MONJU steam generator. Three kinds of analyses were performed with the view to showing the integrity of the steam generator system on the reaction. The first one is the analysis of the initial pressure spike, assuming the initial guillotine rupture of 1 tube. The analysis was performed by utilizing one-dimensional sphere-cylinder model code SWAC-7 and two-dimensional axisymmetric code PISCES 2DL. The second one is the analysis of the secondary peak pressure and its propagation in the system, assuming the instantaneous guillotine rupture of 4 tubes. The third one is the analysis of the dynamic deformation of the steam generator shell. The integrity of the steam generator system was shown by the analyses. (author)

  18. Application of Load Compensation in Voltage Controllers of Large Generators in the Polish Power Grid

    Directory of Open Access Journals (Sweden)

    Bogdan Sobczak

    2014-03-01

    Full Text Available The Automatic Voltage Regulator normally controls the generator stator terminal voltage. Load compensation is used to control the voltage which is representative of the voltage at a point either within or external to the generator. In the Polish Power Grid (PPG compensation is ready to use in every AVR of a large generator, but it is utilized only in the case of generators operating at the same medium voltage buses. It is similar as in most European Power Grids. The compensator regulating the voltage at a point beyond the machine terminals has significant advantages in comparison to the slower secondary Voltage and Reactive Power Control System (ARNE1. The compensation stiffens the EHV grid, which leads to improved voltage quality in the distribution grid. This effect may be particularly important in the context of the dynamic development of wind and solar energy.

  19. Large-leak sodium-water reaction analysis for steam generators

    International Nuclear Information System (INIS)

    Sakano, K.; Shindo, Y.; Hori, M.

    1975-01-01

    The guillotine rupture of 4 tubes is assumed as a design basis regarding the large-leak sodium-water reaction in the system of the MONJU steam generator. Three kinds of analyses were performed with the view to showing the integrity of the steam generator system on the reaction. The first one is the analysis of the initial pressure spike, assuming the initial guillotine rupture of 1 tube. The analysis was performed by utilizing one-dimensional sphere-cylinder model code SWAC-7 and two-dimensional axisymmetric code PISCES 2DL. The second one is the analysis of the secondary peak pressure and its propagation in the system, assuming the instantaneous guillotine rupture of 4 tubes. The third one is the analysis of the dynamic deformation of the steam generator shell. The integrity of the steam generator system was shown by the analyses. (author)

  20. ASP - Grid connections of large power generating units; ASP - Anslutning av stoerre produktionsanlaeggningar till elnaetet

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Aake; Larsson, Richard [Vattenfall Power Consultants, Stockholm (Sweden)

    2006-12-15

    Grid connections of large power generating units normally require more detailed studies compared to small single units. The required R and D-level depends on the specific characteristics of the production units and the connecting grid. An inquiry for a grid connection will raise questions for the grid owner regarding transmission capability, losses, fault currents, relay protection, dynamic stability etc. Then only a few larger wind farms have been built, the experiences from these types of grid connections are limited and for that reason it can be difficult to identify issues appropriate for further studies. To ensure that electric power generating units do not have unacceptable impact on the grid, directions from the Swedish TSO (Svenska Kraftnaet) have been stated. The directions deal, for example, with power generation in specific ranges of voltage level and frequency and the possibility to remain connected to the grid when different faults occur. The requirements and the consequences of these directions are illustrated. There are three main issues that should be considered: Influence on the power flow from generating units regarding voltage level, currents, losses etc.; Different types of electric systems in generating units contribute to different levels of fault currents. For that reason the resulting fault current levels have to be studied; It is required that generating units should remain connected to the grid at different modes of operation and faults. These modes have to be verified. Load flow and dynamic studies normally demand computer models. Comprehensive models, for instance of wind farms, can bee difficult to design and normally large computer capacity is required. Therefore simplified methods to perform relevant studies are described. How to model an electric power generating unit regarding fault currents and dynamic stability is described. An inquiry for a grid connection normally brings about a discussion concerning administration. To make it

  1. Generation Expansion Planning With Large Amounts of Wind Power via Decision-Dependent Stochastic Programming

    Energy Technology Data Exchange (ETDEWEB)

    Zhan, Yiduo; Zheng, Qipeng P.; Wang, Jianhui; Pinson, Pierre

    2017-07-01

    Power generation expansion planning needs to deal with future uncertainties carefully, given that the invested generation assets will be in operation for a long time. Many stochastic programming models have been proposed to tackle this challenge. However, most previous works assume predetermined future uncertainties (i.e., fixed random outcomes with given probabilities). In several recent studies of generation assets' planning (e.g., thermal versus renewable), new findings show that the investment decisions could affect the future uncertainties as well. To this end, this paper proposes a multistage decision-dependent stochastic optimization model for long-term large-scale generation expansion planning, where large amounts of wind power are involved. In the decision-dependent model, the future uncertainties are not only affecting but also affected by the current decisions. In particular, the probability distribution function is determined by not only input parameters but also decision variables. To deal with the nonlinear constraints in our model, a quasi-exact solution approach is then introduced to reformulate the multistage stochastic investment model to a mixed-integer linear programming model. The wind penetration, investment decisions, and the optimality of the decision-dependent model are evaluated in a series of multistage case studies. The results show that the proposed decision-dependent model provides effective optimization solutions for long-term generation expansion planning.

  2. Analytical treatment of large leak pressure behavior in LMFBR steam generators

    International Nuclear Information System (INIS)

    Hori, Masao; Miyake, Osamu

    1980-07-01

    Simplified analytical methods applicable to the estimation of initial pressure spike in case of a large leak accident in LMFBR steam generators were devised as follows; (i) Estimation of the initial water leak rate by the centered rarefaction wave method, (ii) Estimation of the initial pressure spike by the one-dimensional compressible method with either the columnar bubble growth model or the spherical bubble growth model. These methods were compared with relevant experimental data or other more elaborate analyses and validated to be usable in simple geometry and limited time span cases. Application of these methods to an actual steam generator case was explained and demonstrated. (author)

  3. Scheduling of power generation a large-scale mixed-variable model

    CERN Document Server

    Prékopa, András; Strazicky, Beáta; Deák, István; Hoffer, János; Németh, Ágoston; Potecz, Béla

    2014-01-01

    The book contains description of a real life application of modern mathematical optimization tools in an important problem solution for power networks. The objective is the modelling and calculation of optimal daily scheduling of power generation, by thermal power plants,  to satisfy all demands at minimum cost, in such a way that the  generation and transmission capacities as well as the demands at the nodes of the system appear in an integrated form. The physical parameters of the network are also taken into account. The obtained large-scale mixed variable problem is relaxed in a smart, practical way, to allow for fast numerical solution of the problem.

  4. Large scale sodium-water reaction tests for Monju steam generators

    International Nuclear Information System (INIS)

    Sato, M.; Hiroi, H.; Hori, M.

    1976-01-01

    To demonstrate the safe design of the steam generator system of the prototype fast reactor Monju against the postulated large leak sodium-water reaction, a large scale test facility SWAT-3 was constructed. SWAT-3 is a 1/2.5 scale model of the Monju secondary loop on the basis of the iso-velocity modeling. Two tests have been conducted in SWAT-3 since its construction. The test items using SWAT-3 are discussed, and the description of the facility and the test results are presented

  5. Visualization of the Flux Rope Generation Process Using Large Quantities of MHD Simulation Data

    Directory of Open Access Journals (Sweden)

    Y Kubota

    2013-03-01

    Full Text Available We present a new concept of analysis using visualization of large quantities of simulation data. The time development of 3D objects with high temporal resolution provides the opportunity for scientific discovery. We visualize large quantities of simulation data using the visualization application 'Virtual Aurora' based on AVS (Advanced Visual Systems and the parallel distributed processing at "Space Weather Cloud" in NICT based on Gfarm technology. We introduce two results of high temporal resolution visualization: the magnetic flux rope generation process and dayside reconnection using a system of magnetic field line tracing.

  6. Development and tests of large nuclear turbo-generator welded rotors

    International Nuclear Information System (INIS)

    Colombie, H.; Thiery, M.; Rotzinger, R.; Pelissou, C.; Tabacco, C.; Fernagut, V.

    2015-01-01

    Turbo-generators require large forgings for the rotor and it is a worldwide practice to manufacture turbo-generator rotor bodies as single piece forgings. Rotors for nuclear applications (4-pole rotors design, 1500/1800 rpm) require forgings of up to 2.0 m diameter and ultra large ingots with weight more than 500 tons. Nowadays only few forge masters can deliver such forgings in the world. Based on the large welding experience Alstom has gained over decades on steam and gas turbines and Alstom's multi piece shrunk turbo-generator rotors, it was suggested to manufacture 4-pole turbo-generator rotors by welding the shaft from aligned cylindrical forgings. Compared to turbine welded rotors, the shaft of a turbo-generator rotor presents differences linked to dimensions/weight, weld depth and electrical application. The manufacture of a 2 disc model allowed to prove through electrical and mechanical analysis the reliability of the concept as well as the reliability of the manufacturing processes through material tests, micro sections, electrical component tests, weld geometry, welding processes (TIG,SAW,...), weld inspection (Ultrasonic testing, radiographic inspection,...) weld heat treatments and machining. Then a full rotor able to replace a single forging rotor was manufactured in order to validate and prove to potential customers the validity of the welded rotor technology. During the first order from EDF of a welded 900 MW spare rotor, the procedure for the Non Destructive Test on a slotted rotor was developed upon EDF request in order to compare future Non Destructive Testing with the finger print of the new rotor. This complete rotor was delivered to EDF in January 2013. This rotor is in operation in a nuclear unit since November 2013. (authors)

  7. Towards Rapid Generation and Visualisation of Large 3D Urban Landscapes for Mobile Device Navigation

    OpenAIRE

    Brujic-Okretic, V.; Gatzidis, C.; Liarokapis, F.; Baker, S.

    2008-01-01

    In this paper a procedural 3D modelling solution for mobile devices is presented based on scripting algorithms allowing for both the automatic and also semi-automatic creation of photorealistic quality virtual urban content. The combination of aerial images, GIS data, 2D ground maps and terrestrial photographs as input data coupled with a user-friendly customized interface permits the automatic and interactive generation of large-scale, accurate, georeferenced and fully-textured 3D virtual ci...

  8. Large area imaging of hydrogenous materials using fast neutrons from a DD fusion generator

    Energy Technology Data Exchange (ETDEWEB)

    Cremer, J.T., E-mail: ted@adelphitech.com [Adelphi Technology Inc., 2003 East Bayshore Road, Redwood City, California 94063 (United States); Williams, D.L.; Gary, C.K.; Piestrup, M.A.; Faber, D.R.; Fuller, M.J.; Vainionpaa, J.H.; Apodaca, M. [Adelphi Technology Inc., 2003 East Bayshore Road, Redwood City, California 94063 (United States); Pantell, R.H.; Feinstein, J. [Department of Electrical Engineering, Stanford University, Stanford, California 94305 (United States)

    2012-05-21

    A small-laboratory fast-neutron generator and a large area detector were used to image hydrogen-bearing materials. The overall image resolution of 2.5 mm was determined by a knife-edge measurement. Contact images of objects were obtained in 5-50 min exposures by placing them close to a plastic scintillator at distances of 1.5 to 3.2 m from the neutron source. The generator produces 10{sup 9} n/s from the DD fusion reaction at a small target. The combination of the DD-fusion generator and electronic camera permits both small laboratory and field-portable imaging of hydrogen-rich materials embedded in high density materials.

  9. New Earth-abundant Materials for Large-scale Solar Fuels Generation.

    Science.gov (United States)

    Prabhakar, Rajiv Ramanujam; Cui, Wei; Tilley, S David

    2018-05-30

    The solar resource is immense, but the power density of light striking the Earth's surface is relatively dilute, necessitating large area solar conversion devices in order to harvest substantial amounts of power for renewable energy applications. In addition, energy storage is a key challenge for intermittent renewable resources such as solar and wind, which adds significant cost to these energies. As the majority of humanity's present-day energy consumption is based on fuels, an ideal solution is to generate renewable fuels from abundant resources such as sunlight and water. In this account, we detail our recent work towards generating highly efficient and stable Earth-abundant semiconducting materials for solar water splitting to generate renewable hydrogen fuel.

  10. Generation of weakly nonlinear nonhydrostatic internal tides over large topography: a multi-modal approach

    Directory of Open Access Journals (Sweden)

    R. Maugé

    2008-03-01

    Full Text Available A set of evolution equations is derived for the modal coefficients in a weakly nonlinear nonhydrostatic internal-tide generation problem. The equations allow for the presence of large-amplitude topography, e.g. a continental slope, which is formally assumed to have a length scale much larger than that of the internal tide. However, comparison with results from more sophisticated numerical models show that this restriction can in practice be relaxed. It is shown that a topographically induced coupling between modes occurs that is distinct from nonlinear coupling. Nonlinear effects include the generation of higher harmonics by reflection from boundaries, i.e. steeper tidal beams at frequencies that are multiples of the basic tidal frequency. With a seasonal thermocline included, the model is capable of reproducing the phenomenon of local generation of internal solitary waves by a tidal beam impinging on the seasonal thermocline.

  11. Large-scale runoff generation - parsimonious parameterisation using high-resolution topography

    Science.gov (United States)

    Gong, L.; Halldin, S.; Xu, C.-Y.

    2011-08-01

    World water resources have primarily been analysed by global-scale hydrological models in the last decades. Runoff generation in many of these models are based on process formulations developed at catchments scales. The division between slow runoff (baseflow) and fast runoff is primarily governed by slope and spatial distribution of effective water storage capacity, both acting at very small scales. Many hydrological models, e.g. VIC, account for the spatial storage variability in terms of statistical distributions; such models are generally proven to perform well. The statistical approaches, however, use the same runoff-generation parameters everywhere in a basin. The TOPMODEL concept, on the other hand, links the effective maximum storage capacity with real-world topography. Recent availability of global high-quality, high-resolution topographic data makes TOPMODEL attractive as a basis for a physically-based runoff-generation algorithm at large scales, even if its assumptions are not valid in flat terrain or for deep groundwater systems. We present a new runoff-generation algorithm for large-scale hydrology based on TOPMODEL concepts intended to overcome these problems. The TRG (topography-derived runoff generation) algorithm relaxes the TOPMODEL equilibrium assumption so baseflow generation is not tied to topography. TRG only uses the topographic index to distribute average storage to each topographic index class. The maximum storage capacity is proportional to the range of topographic index and is scaled by one parameter. The distribution of storage capacity within large-scale grid cells is obtained numerically through topographic analysis. The new topography-derived distribution function is then inserted into a runoff-generation framework similar VIC's. Different basin parts are parameterised by different storage capacities, and different shapes of the storage-distribution curves depend on their topographic characteristics. The TRG algorithm is driven by the

  12. Large-scale runoff generation – parsimonious parameterisation using high-resolution topography

    Directory of Open Access Journals (Sweden)

    L. Gong

    2011-08-01

    Full Text Available World water resources have primarily been analysed by global-scale hydrological models in the last decades. Runoff generation in many of these models are based on process formulations developed at catchments scales. The division between slow runoff (baseflow and fast runoff is primarily governed by slope and spatial distribution of effective water storage capacity, both acting at very small scales. Many hydrological models, e.g. VIC, account for the spatial storage variability in terms of statistical distributions; such models are generally proven to perform well. The statistical approaches, however, use the same runoff-generation parameters everywhere in a basin. The TOPMODEL concept, on the other hand, links the effective maximum storage capacity with real-world topography. Recent availability of global high-quality, high-resolution topographic data makes TOPMODEL attractive as a basis for a physically-based runoff-generation algorithm at large scales, even if its assumptions are not valid in flat terrain or for deep groundwater systems. We present a new runoff-generation algorithm for large-scale hydrology based on TOPMODEL concepts intended to overcome these problems. The TRG (topography-derived runoff generation algorithm relaxes the TOPMODEL equilibrium assumption so baseflow generation is not tied to topography. TRG only uses the topographic index to distribute average storage to each topographic index class. The maximum storage capacity is proportional to the range of topographic index and is scaled by one parameter. The distribution of storage capacity within large-scale grid cells is obtained numerically through topographic analysis. The new topography-derived distribution function is then inserted into a runoff-generation framework similar VIC's. Different basin parts are parameterised by different storage capacities, and different shapes of the storage-distribution curves depend on their topographic characteristics. The TRG algorithm

  13. Size Reduction Techniques for Large Scale Permanent Magnet Generators in Wind Turbines

    Science.gov (United States)

    Khazdozian, Helena; Hadimani, Ravi; Jiles, David

    2015-03-01

    Increased wind penetration is necessary to reduce U.S. dependence on fossil fuels, combat climate change and increase national energy security. The U.S Department of Energy has recommended large scale and offshore wind turbines to achieve 20% wind electricity generation by 2030. Currently, geared doubly-fed induction generators (DFIGs) are typically employed in the drivetrain for conversion of mechanical to electrical energy. Yet, gearboxes account for the greatest downtime of wind turbines, decreasing reliability and contributing to loss of profit. Direct drive permanent magnet generators (PMGs) offer a reliable alternative to DFIGs by eliminating the gearbox. However, PMGs scale up in size and weight much more rapidly than DFIGs as rated power is increased, presenting significant challenges for large scale wind turbine application. Thus, size reduction techniques are needed for viability of PMGs in large scale wind turbines. Two size reduction techniques are presented. It is demonstrated that 25% size reduction of a 10MW PMG is possible with a high remanence theoretical permanent magnet. Additionally, the use of a Halbach cylinder in an outer rotor PMG is investigated to focus magnetic flux over the rotor surface in order to increase torque. This work was supported by the National Science Foundation under Grant No. 1069283 and a Barbara and James Palmer Endowment at Iowa State University.

  14. An improved yeast transformation method for the generation of very large human antibody libraries.

    Science.gov (United States)

    Benatuil, Lorenzo; Perez, Jennifer M; Belk, Jonathan; Hsieh, Chung-Ming

    2010-04-01

    Antibody library selection by yeast display technology is an efficient and highly sensitive method to identify binders to target antigens. This powerful selection tool, however, is often hampered by the typically modest size of yeast libraries (approximately 10(7)) due to the limited yeast transformation efficiency, and the full potential of the yeast display technology for antibody discovery and engineering can only be realized if it can be coupled with a mean to generate very large yeast libraries. We describe here a yeast transformation method by electroporation that allows for the efficient generation of large antibody libraries up to 10(10) in size. Multiple components and conditions including CaCl(2), MgCl(2), sucrose, sorbitol, lithium acetate, dithiothreitol, electroporation voltage, DNA input and cell volume have been tested to identify the best combination. By applying this developed protocol, we have constructed a 1.4 x 10(10) human spleen antibody library essentially in 1 day with a transformation efficiency of 1-1.5 x 10(8) transformants/microg vector DNA. Taken together, we have developed a highly efficient yeast transformation method that enables the generation of very large and productive human antibody libraries for antibody discovery, and we are now routinely making 10(9) libraries in a day for antibody engineering purposes.

  15. Status of the technology development of large scale HTS generators for wind turbine

    Energy Technology Data Exchange (ETDEWEB)

    Le, T. D.; Kim, J. H.; Kim, D. J.; Boo, C. J.; Kim, H. M. [Jeju National University, Jeju (Korea, Republic of)

    2015-06-15

    Large wind turbine generators with high temperature superconductors (HTS) are in incessant development because of their advantages such as weight and volume reduction and the increased efficiency compared with conventional technologies. In addition, nowadays the wind turbine market is growing in a function of time, increasing the capacity and energy production of the wind farms installed and increasing the electrical power for the electrical generators installed. As a consequence, it is raising the wind power energy contribution for the global electricity demand. In this study, a forecast of wind energy development will be firstly emphasized, then it continue presenting a recent status of the technology development of large scale HTSG for wind power followed by an explanation of HTS wire trend, cryogenics cooling systems concept, HTS magnets field coil stability and other technological parts for optimization of HTS generator design-operating temperature, design topology, field coil shape and level cost of energy, as well. Finally, the most relevant projects and designs of HTS generators specifically for offshore wind power systems are also mentioned in this study.

  16. Status of the technology development of large scale HTS generators for wind turbine

    International Nuclear Information System (INIS)

    Le, T. D.; Kim, J. H.; Kim, D. J.; Boo, C. J.; Kim, H. M.

    2015-01-01

    Large wind turbine generators with high temperature superconductors (HTS) are in incessant development because of their advantages such as weight and volume reduction and the increased efficiency compared with conventional technologies. In addition, nowadays the wind turbine market is growing in a function of time, increasing the capacity and energy production of the wind farms installed and increasing the electrical power for the electrical generators installed. As a consequence, it is raising the wind power energy contribution for the global electricity demand. In this study, a forecast of wind energy development will be firstly emphasized, then it continue presenting a recent status of the technology development of large scale HTSG for wind power followed by an explanation of HTS wire trend, cryogenics cooling systems concept, HTS magnets field coil stability and other technological parts for optimization of HTS generator design-operating temperature, design topology, field coil shape and level cost of energy, as well. Finally, the most relevant projects and designs of HTS generators specifically for offshore wind power systems are also mentioned in this study

  17. Particle generation methods applied in large-scale experiments on aerosol behaviour and source term studies

    International Nuclear Information System (INIS)

    Swiderska-Kowalczyk, M.; Gomez, F.J.; Martin, M.

    1997-01-01

    In aerosol research aerosols of known size, shape, and density are highly desirable because most aerosols properties depend strongly on particle size. However, such constant and reproducible generation of those aerosol particles whose size and concentration can be easily controlled, can be achieved only in laboratory-scale tests. In large scale experiments, different generation methods for various elements and compounds have been applied. This work presents, in a brief from, a review of applications of these methods used in large scale experiments on aerosol behaviour and source term. Description of generation method and generated aerosol transport conditions is followed by properties of obtained aerosol, aerosol instrumentation used, and the scheme of aerosol generation system-wherever it was available. An information concerning aerosol generation particular purposes and reference number(s) is given at the end of a particular case. These methods reviewed are: evaporation-condensation, using a furnace heating and using a plasma torch; atomization of liquid, using compressed air nebulizers, ultrasonic nebulizers and atomization of liquid suspension; and dispersion of powders. Among the projects included in this worked are: ACE, LACE, GE Experiments, EPRI Experiments, LACE-Spain. UKAEA Experiments, BNWL Experiments, ORNL Experiments, MARVIKEN, SPARTA and DEMONA. The aim chemical compounds studied are: Ba, Cs, CsOH, CsI, Ni, Cr, NaI, TeO 2 , UO 2 Al 2 O 3 , Al 2 SiO 5 , B 2 O 3 , Cd, CdO, Fe 2 O 3 , MnO, SiO 2 , AgO, SnO 2 , Te, U 3 O 8 , BaO, CsCl, CsNO 3 , Urania, RuO 2 , TiO 2 , Al(OH) 3 , BaSO 4 , Eu 2 O 3 and Sn. (Author)

  18. HiQuant: Rapid Postquantification Analysis of Large-Scale MS-Generated Proteomics Data.

    Science.gov (United States)

    Bryan, Kenneth; Jarboui, Mohamed-Ali; Raso, Cinzia; Bernal-Llinares, Manuel; McCann, Brendan; Rauch, Jens; Boldt, Karsten; Lynn, David J

    2016-06-03

    Recent advances in mass-spectrometry-based proteomics are now facilitating ambitious large-scale investigations of the spatial and temporal dynamics of the proteome; however, the increasing size and complexity of these data sets is overwhelming current downstream computational methods, specifically those that support the postquantification analysis pipeline. Here we present HiQuant, a novel application that enables the design and execution of a postquantification workflow, including common data-processing steps, such as assay normalization and grouping, and experimental replicate quality control and statistical analysis. HiQuant also enables the interpretation of results generated from large-scale data sets by supporting interactive heatmap analysis and also the direct export to Cytoscape and Gephi, two leading network analysis platforms. HiQuant may be run via a user-friendly graphical interface and also supports complete one-touch automation via a command-line mode. We evaluate HiQuant's performance by analyzing a large-scale, complex interactome mapping data set and demonstrate a 200-fold improvement in the execution time over current methods. We also demonstrate HiQuant's general utility by analyzing proteome-wide quantification data generated from both a large-scale public tyrosine kinase siRNA knock-down study and an in-house investigation into the temporal dynamics of the KSR1 and KSR2 interactomes. Download HiQuant, sample data sets, and supporting documentation at http://hiquant.primesdb.eu .

  19. Comparative funding consequences of large versus small gas-fired power generation units

    International Nuclear Information System (INIS)

    Johnson, N.G.

    1995-01-01

    Gas producers are increasingly looking to privately-owned gas-fired power generation as a major growth market to support the development of new fields being discovered across Australia. Gas-fired generating technology is more environmentally friendly than coal-fired power stations, has lower unit capital costs and has higher efficiency levels. With the recent downward trends in gas prices for power generation (especially in Western Australia) it is likely that gas will indeed be the consistently preferred fuel for generation in Australia. Gas producers should be sensitive to the different financial and risk characteristics of the potential market represented by large versus small gas-fired private power stations. These differences are exaggerated by the much sharper focus given by the private sector to quantify risk and to its allocation to the parties best able to manage it. The significant commercial differences between classes of generation projects result in gas producers themselves being exposed to diverging risk profiles through their gas supply contracts with generating companies. Selling gas to larger generation units results in gas suppliers accepting proportionately (i.e. not just prorata to the larger installed capacity) higher levels of financial risk. Risk arises from the higher probability of a project not being completed, from the increased size of penalty payments associated with non-delivery of gas and from the rising level of competition between gas suppliers. Gas producers must fully understand the economics and risks of their potential electricity customers and full financial analysis will materially help the gas supplier in subsequent commercial gas contract negotiations. (author). 1 photo

  20. Use of a large-scale rainfall simulator reveals novel insights into stemflow generation

    Science.gov (United States)

    Levia, D. F., Jr.; Iida, S. I.; Nanko, K.; Sun, X.; Shinohara, Y.; Sakai, N.

    2017-12-01

    Detailed knowledge of stemflow generation and its effects on both hydrological and biogoechemical cycling is important to achieve a holistic understanding of forest ecosystems. Field studies and a smaller set of experiments performed under laboratory conditions have increased our process-based knowledge of stemflow production. Building upon these earlier works, a large-scale rainfall simulator was employed to deepen our understanding of stemflow generation processes. The use of the large-scale rainfall simulator provides a unique opportunity to examine a range of rainfall intensities under constant conditions that are difficult under natural conditions due to the variable nature of rainfall intensities in the field. Stemflow generation and production was examined for three species- Cryptomeria japonica D. Don (Japanese cedar), Chamaecyparis obtusa (Siebold & Zucc.) Endl. (Japanese cypress), Zelkova serrata Thunb. (Japanese zelkova)- under both leafed and leafless conditions at several different rainfall intensities (15, 20, 30, 40, 50, and 100 mm h-1) using a large-scale rainfall simulator in National Research Institute for Earth Science and Disaster Resilience (Tsukuba, Japan). Stemflow production and rates and funneling ratios were examined in relation to both rainfall intensity and canopy structure. Preliminary results indicate a dynamic and complex response of the funneling ratios of individual trees to different rainfall intensities among the species examined. This is partly the result of different canopy structures, hydrophobicity of vegetative surfaces, and differential wet-up processes across species and rainfall intensities. This presentation delves into these differences and attempts to distill them into generalizable patterns, which can advance our theories of stemflow generation processes and ultimately permit better stewardship of forest resources. ________________ Funding note: This research was supported by JSPS Invitation Fellowship for Research in

  1. Outsourcing of generating assets as a competitive strategy for large electric customers

    Energy Technology Data Exchange (ETDEWEB)

    Giacalone, F.T.; Hocker, C.

    1998-07-01

    The US electric power industry is at a transitional stage on the way to full competition at the retail level. A fundamental difference between wholesale and retail competition is that, with the latter, the end user will have a choice of suppliers. Large electric customers, such as industrial manufacturers, have traditionally had only two choices: to purchase from the local franchise utility or to self-generate. With retail competition, however, these same customers will have not only have many choices of suppliers to compare against the self-generation option, but also will have a new alternative to consider - that of outsourcing their generating assets as a means of retaining effective control, but not necessarily ownership, of their electric supply. Outsourcing of generation assets means turning over complete or partial ownership of these assets to a third party, who then sells the electricity back to the customer at retail. This approach can be advantageous to a customer who wants to achieve one or more of the following benefits that are generally not available in the traditional ``make or buy'' paradigm: monetize (receive cash for) assets to pay down debt or redeploy into its core business; reduce operating and overhead costs; meet increasing power demand without making a significant capital expenditure; retain a significant degree of control over the operation of the assets, rather than turning its source of supply to a utility, independent generator, or power marketer; and move the assets off-balance sheet and off-credit as a means of improving its corporate financial position. Outsourcing of industrial generation, including most or all of the above benefits has already occurred successfully in a handful of cases, such as the James River and Stone Container mills discussed in this paper.

  2. Outsourcing of generating assets as a competitive strategy for large electric customers

    International Nuclear Information System (INIS)

    Giacalone, F.T.; Hocker, C.

    1998-01-01

    The US electric power industry is at a transitional stage on the way to full competition at the retail level. A fundamental difference between wholesale and retail competition is that, with the latter, the end user will have a choice of suppliers. Large electric customers, such as industrial manufacturers, have traditionally had only two choices: to purchase from the local franchise utility or to self-generate. With retail competition, however, these same customers will have not only have many choices of suppliers to compare against the self-generation option, but also will have a new alternative to consider - that of outsourcing their generating assets as a means of retaining effective control, but not necessarily ownership, of their electric supply. Outsourcing of generation assets means turning over complete or partial ownership of these assets to a third party, who then sells the electricity back to the customer at retail. This approach can be advantageous to a customer who wants to achieve one or more of the following benefits that are generally not available in the traditional ''make or buy'' paradigm: monetize (receive cash for) assets to pay down debt or redeploy into its core business; reduce operating and overhead costs; meet increasing power demand without making a significant capital expenditure; retain a significant degree of control over the operation of the assets, rather than turning its source of supply to a utility, independent generator, or power marketer; and move the assets off-balance sheet and off-credit as a means of improving its corporate financial position. Outsourcing of industrial generation, including most or all of the above benefits has already occurred successfully in a handful of cases, such as the James River and Stone Container mills discussed in this paper

  3. Large Eddy Simulation of Entropy Generation in a Turbulent Mixing Layer

    Science.gov (United States)

    Sheikhi, Reza H.; Safari, Mehdi; Hadi, Fatemeh

    2013-11-01

    Entropy transport equation is considered in large eddy simulation (LES) of turbulent flows. The irreversible entropy generation in this equation provides a more general description of subgrid scale (SGS) dissipation due to heat conduction, mass diffusion and viscosity effects. A new methodology is developed, termed the entropy filtered density function (En-FDF), to account for all individual entropy generation effects in turbulent flows. The En-FDF represents the joint probability density function of entropy, frequency, velocity and scalar fields within the SGS. An exact transport equation is developed for the En-FDF, which is modeled by a system of stochastic differential equations, incorporating the second law of thermodynamics. The modeled En-FDF transport equation is solved by a Lagrangian Monte Carlo method. The methodology is employed to simulate a turbulent mixing layer involving transport of passive scalars and entropy. Various modes of entropy generation are obtained from the En-FDF and analyzed. Predictions are assessed against data generated by direct numerical simulation (DNS). The En-FDF predictions are in good agreements with the DNS data.

  4. Statistical Modeling of Large Wind Plant System's Generation - A Case Study

    International Nuclear Information System (INIS)

    Sabolic, D.

    2014-01-01

    This paper presents simplistic, yet very accurate, descriptive statistical models of various static and dynamic parameters of energy output from a large system of wind plants operated by Bonneville Power Administration (BPA), USA. The system's size at the end of 2013 was 4515 MW of installed capacity. The 5-minute readings from the beginning of 2007 to the end of 2013, recorded and published by BPA, were used to derive a number of experimental distributions, which were then used to devise theoretic statistical models with merely one or two parameters. In spite of the simplicity, they reproduced experimental data with great accuracy, which was checked by rigorous tests of goodness-of-fit. Statistical distribution functions were obtained for the following wind generation-related quantities: total generation as percentage of total installed capacity; change in total generation power in 5, 10, 15, 20, 25, 30, 45, and 60 minutes as percentage of total installed capacity; duration of intervals with total generated power, expressed as percentage of total installed capacity, lower than certain pre-specified level. Limitation of total installed wind plant capacity, when it is determined by regulation demand from wind plants, is discussed, too. The models presented here can be utilized in analyses related to power system economics/policy, which is also briefly discussed in the paper. (author).

  5. Random number generators for large-scale parallel Monte Carlo simulations on FPGA

    Science.gov (United States)

    Lin, Y.; Wang, F.; Liu, B.

    2018-05-01

    Through parallelization, field programmable gate array (FPGA) can achieve unprecedented speeds in large-scale parallel Monte Carlo (LPMC) simulations. FPGA presents both new constraints and new opportunities for the implementations of random number generators (RNGs), which are key elements of any Monte Carlo (MC) simulation system. Using empirical and application based tests, this study evaluates all of the four RNGs used in previous FPGA based MC studies and newly proposed FPGA implementations for two well-known high-quality RNGs that are suitable for LPMC studies on FPGA. One of the newly proposed FPGA implementations: a parallel version of additive lagged Fibonacci generator (Parallel ALFG) is found to be the best among the evaluated RNGs in fulfilling the needs of LPMC simulations on FPGA.

  6. Generation of large scale GHZ states with the interactions of photons and quantum-dot spins

    Science.gov (United States)

    Miao, Chun; Fang, Shu-Dong; Dong, Ping; Yang, Ming; Cao, Zhuo-Liang

    2018-03-01

    We present a deterministic scheme for generating large scale GHZ states in a cavity-quantum dot system. A singly charged quantum dot is embedded in a double-sided optical microcavity with partially reflective top and bottom mirrors. The GHZ-type Bell spin state can be created and two n-spin GHZ states can be perfectly fused to a 2n-spin GHZ state with the help of n ancilla single-photon pulses. The implementation of the current scheme only depends on the photon detection and its need not to operate multi-qubit gates and multi-qubit measurements. Discussions about the effect of the cavity loss, side leakage and exciton cavity coupling strength for the fidelity of generated states show that the fidelity can remain high enough by controlling system parameters. So the current scheme is simple and feasible in experiment.

  7. Study for a failsafe trigger generation system for the Large Hadron Collider beam dump kicker magnets

    CERN Document Server

    Rampl, M

    1999-01-01

    The 27 km-particle accelerator Large Hadron Collider (LHC), which will be completed at the European Laboratory for Particle Physics (CERN) in 2005, will work with extremely high beam energies (~334 MJ per beam). Since the equipment and in particular the superconducting magnets must be protected from damage caused by these high energy beams the beam dump must be able to absorb this energy very reliable at every stage of operation. The kicker magnets that extract the particles from the accelerator are synchronised with the beam by the trigger generation system. This thesis is a first study for this electronic module and its functions. A special synchronisation circuit and a very reliable electronic switch were developed. Most functions were implemented in a Gate-Array to improve the reliability and to facilitate modifications during the test stage. This study also comprises the complete concept for the prototype of the trigger generation system. During all project stages reliability was always the main determin...

  8. Generation of pyroclastic density currents from pyroclastic fountaining or transient explosions: insights from large scale experiments

    Energy Technology Data Exchange (ETDEWEB)

    Sulpizio, Roberto; Dellino, Pierfrancesco; Mele, Daniela; La Volpe, Luigi [CIRISIVU, c/o Dipartimento Geomineralogico, via Orabona 4, 70125, Bari (Italy)], E-mail: r.sulpizio@geomin.uniba.it

    2008-10-01

    Pyroclastic density currents (PDCs) are among the most amazing, complex and dangerous volcanic phenomena. They are moving mixtures of particles and gas that flow across the ground, and originate in different ways and from various sources, during explosive eruptions or gravity-driven collapse of domes. We present results from experimental work to investigate the generation of large-scale, multiphase, gravity-driven currents. The experiments described here are particularly devoted to understanding the inception and development of PDCs under impulsive injection conditions by means of the fast application of a finite stress to a finite mass of pyroclastic particles via expansion of compressed gas. We find that, in summary, PDC generation from collapse of pressure-adjusted or overpressurised pyroclastic jets critically depends on behaviour of injection into the atmosphere, which controls the collapsing mechanisms and then the physical parameters of the initiating current.

  9. Full-color large-scaled computer-generated holograms using RGB color filters.

    Science.gov (United States)

    Tsuchiyama, Yasuhiro; Matsushima, Kyoji

    2017-02-06

    A technique using RGB color filters is proposed for creating high-quality full-color computer-generated holograms (CGHs). The fringe of these CGHs is composed of more than a billion pixels. The CGHs reconstruct full-parallax three-dimensional color images with a deep sensation of depth caused by natural motion parallax. The simulation technique as well as the principle and challenges of high-quality full-color reconstruction are presented to address the design of filter properties suitable for large-scaled CGHs. Optical reconstructions of actual fabricated full-color CGHs are demonstrated in order to verify the proposed techniques.

  10. Rucio - The next generation large scale distributed system for ATLAS Data Management

    CERN Document Server

    Beermann, T; The ATLAS collaboration; Lassnig, M; Barisits, M; Vigne, R; Serfon, C; Stewart, G A; Goossens, L; Nairz, A; Molfetas, A

    2014-01-01

    Rucio is the next-generation Distributed Data Management (DDM) system benefiting from recent advances in cloud and "Big Data" computing to address the ATLAS experiment scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 150 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will deal with these issues by relying on new technologies to ensure system scalability, address new user requirements and employ a new automation framework to reduce operational overheads.

  11. A method for generating large datasets of organ geometries for radiotherapy treatment planning studies

    International Nuclear Information System (INIS)

    Hu, Nan; Cerviño, Laura; Segars, Paul; Lewis, John; Shan, Jinlu; Jiang, Steve; Zheng, Xiaolin; Wang, Ge

    2014-01-01

    With the rapidly increasing application of adaptive radiotherapy, large datasets of organ geometries based on the patient’s anatomy are desired to support clinical application or research work, such as image segmentation, re-planning, and organ deformation analysis. Sometimes only limited datasets are available in clinical practice. In this study, we propose a new method to generate large datasets of organ geometries to be utilized in adaptive radiotherapy. Given a training dataset of organ shapes derived from daily cone-beam CT, we align them into a common coordinate frame and select one of the training surfaces as reference surface. A statistical shape model of organs was constructed, based on the establishment of point correspondence between surfaces and non-uniform rational B-spline (NURBS) representation. A principal component analysis is performed on the sampled surface points to capture the major variation modes of each organ. A set of principal components and their respective coefficients, which represent organ surface deformation, were obtained, and a statistical analysis of the coefficients was performed. New sets of statistically equivalent coefficients can be constructed and assigned to the principal components, resulting in a larger geometry dataset for the patient’s organs. These generated organ geometries are realistic and statistically representative

  12. The influence of large-scale electricity generation on man and environment. Ch. 2

    International Nuclear Information System (INIS)

    Brugghen, F.W. van der; Koops, F.B.J.; Steen, J. van der.

    1990-01-01

    In order to be able to make a reliable consideration of the pro's and contra's of nuclear power, this chapter considers the risks of large-scale generation of electricity in general for man and environment. The treatment of this question is limited to the use of fossil fuel at one, and nuclear power at the other hand. Recurring energy sources like the sun and wind are not considered. These are important energy sources, but the planned further application of these sources will not render the contributions of large power plants to the Dutch electricity need in the near future. For the time being recurring energy sources therefore don't play a role in the choice of the type of nuclear reactors to be build in the near future. This limitation however leaves unimpeded that each contribution to the decrease of the burden to the environment, wether it concerns energy saving or application of recurrent energy sources, should be encouraged. When such alternatives can be realized technically and economically, they certainly will form a welcome supplement to the existing power-generation techniques. (author). 6 figs

  13. CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs

    Directory of Open Access Journals (Sweden)

    Djordjevic Marko

    2012-07-01

    Full Text Available Abstract Background CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated sequences is a recently discovered prokaryotic defense system against foreign DNA, including viruses and plasmids. CRISPR cassette is transcribed as a continuous transcript (pre-crRNA, which is processed by Cas proteins into small RNA molecules (crRNAs that are responsible for defense against invading viruses. Experiments in E. coli report that overexpression of cas genes generates a large number of crRNAs, from only few pre-crRNAs. Results We here develop a minimal model of CRISPR processing, which we parameterize based on available experimental data. From the model, we show that the system can generate a large amount of crRNAs, based on only a small decrease in the amount of pre-crRNAs. The relationship between the decrease of pre-crRNAs and the increase of crRNAs corresponds to strong linear amplification. Interestingly, this strong amplification crucially depends on fast non-specific degradation of pre-crRNA by an unidentified nuclease. We show that overexpression of cas genes above a certain level does not result in further increase of crRNA, but that this saturation can be relieved if the rate of CRISPR transcription is increased. We furthermore show that a small increase of CRISPR transcription rate can substantially decrease the extent of cas gene activation necessary to achieve a desired amount of crRNA. Conclusions The simple mathematical model developed here is able to explain existing experimental observations on CRISPR transcript processing in Escherichia coli. The model shows that a competition between specific pre-crRNA processing and non-specific degradation determines the steady-state levels of crRNA and is responsible for strong linear amplification of crRNAs when cas genes are overexpressed. The model further shows how disappearance of only a few pre-crRNA molecules normally present in the cell can lead to a large (two

  14. A large volume uniform plasma generator for the experiments of electromagnetic wave propagation in plasma

    International Nuclear Information System (INIS)

    Yang Min; Li Xiaoping; Xie Kai; Liu Donglin; Liu Yanming

    2013-01-01

    A large volume uniform plasma generator is proposed for the experiments of electromagnetic (EM) wave propagation in plasma, to reproduce a “black out” phenomenon with long duration in an environment of the ordinary laboratory. The plasma generator achieves a controllable approximate uniform plasma in volume of 260 mm× 260 mm× 180 mm without the magnetic confinement. The plasma is produced by the glow discharge, and the special discharge structure is built to bring a steady approximate uniform plasma environment in the electromagnetic wave propagation path without any other barriers. In addition, the electron density and luminosity distributions of plasma under different discharge conditions were diagnosed and experimentally investigated. Both the electron density and the plasma uniformity are directly proportional to the input power and in roughly reverse proportion to the gas pressure in the chamber. Furthermore, the experiments of electromagnetic wave propagation in plasma are conducted in this plasma generator. Blackout phenomena at GPS signal are observed under this system and the measured attenuation curve is of reasonable agreement with the theoretical one, which suggests the effectiveness of the proposed method.

  15. Efficient heat generation in large-area graphene films by electromagnetic wave absorption

    Science.gov (United States)

    Kang, Sangmin; Choi, Haehyun; Lee, Soo Bin; Park, Seong Chae; Park, Jong Bo; Lee, Sangkyu; Kim, Youngsoo; Hong, Byung Hee

    2017-06-01

    Graphene has been intensively studied due to its outstanding electrical and thermal properties. Recently, it was found that the heat generation by Joule heating of graphene is limited by the conductivity of graphene. Here we suggest an alternative method to generate heat on a large-area graphene film more efficiently by utilizing the unique electromagnetic (EM) wave absorption property of graphene. The EM wave induces an oscillating magnetic moment generated by the orbital motion of moving electrons, which efficiently absorbs the EM energy and dissipate it as a thermal energy. In this case, the mobility of electron is more important than the conductivity, because the EM-induced diamagnetic moment is directly proportional to the speed of electron in an orbital motion. To control the charge carrier mobility of graphene we functionalized substrates with self-assembled monolayers (SAM). As the result, we find that the graphene showing the Dirac voltage close to zero can be more efficiently heated by EM waves. In addition, the temperature gradient also depends on the number of graphene. We expect that the efficient and fast heating of graphene films by EM waves can be utilized for smart heating windows and defogging windshields.

  16. A model for steady-state large-volume plasma generation

    International Nuclear Information System (INIS)

    Uhm, H.S.; Miller, J.D.; Schneider, R.F.

    1991-01-01

    In this paper, a simple, new scheme to generate a uniform, steady-state, large-volume plasma is presented. The weakly magnetized plasma is created by direct ionization of the background gas by low-energy electrons generated from thermionic filaments. An annular arrangement of the filaments ensures a uniform plasma density in the radial direction as predicted by theory. Experiments have been performed to characterize the plasma generated in such a configuration. In order to explain the experimental observation, we develop a bulk plasma theory based on plasma transport via cross-field diffusion. As assumed in the theoretical model, the experimental measurements indicate a uniform plasma density along the axis. Both the theory and experiment indicate that the plasma density is a function of the square of the external magnetic field. The theory also predicts the plasma density to be proportional to the neutral density to the two-thirds power in agreement with the experimental data. We also observe the experimental data to agree remarkably well with theoretical prediction for a broad range of system parameters

  17. Automatic Generation of Connectivity for Large-Scale Neuronal Network Models through Structural Plasticity.

    Science.gov (United States)

    Diaz-Pier, Sandra; Naveau, Mikaël; Butz-Ostendorf, Markus; Morrison, Abigail

    2016-01-01

    With the emergence of new high performance computation technology in the last decade, the simulation of large scale neural networks which are able to reproduce the behavior and structure of the brain has finally become an achievable target of neuroscience. Due to the number of synaptic connections between neurons and the complexity of biological networks, most contemporary models have manually defined or static connectivity. However, it is expected that modeling the dynamic generation and deletion of the links among neurons, locally and between different regions of the brain, is crucial to unravel important mechanisms associated with learning, memory and healing. Moreover, for many neural circuits that could potentially be modeled, activity data is more readily and reliably available than connectivity data. Thus, a framework that enables networks to wire themselves on the basis of specified activity targets can be of great value in specifying network models where connectivity data is incomplete or has large error margins. To address these issues, in the present work we present an implementation of a model of structural plasticity in the neural network simulator NEST. In this model, synapses consist of two parts, a pre- and a post-synaptic element. Synapses are created and deleted during the execution of the simulation following local homeostatic rules until a mean level of electrical activity is reached in the network. We assess the scalability of the implementation in order to evaluate its potential usage in the self generation of connectivity of large scale networks. We show and discuss the results of simulations on simple two population networks and more complex models of the cortical microcircuit involving 8 populations and 4 layers using the new framework.

  18. Spontaneous large-scale autolysis in Clostridium acetobutylicum contributes to generation of more spores

    Directory of Open Access Journals (Sweden)

    Zhen eLiu

    2015-09-01

    Full Text Available Autolysis is a widespread phenomenon in bacteria. In batch fermentation of Clostridium acetobutylicum ATCC 824, there is a spontaneous large-scale autolysis phenomenon with significant decrease of cell density immediately after exponential phase. To unravel the role of autolysis, an autolysin-coding gene, CA_C0554, was disrupted by using ClosTron system to obtain the mutant C. acetobutylicum lyc::int(72. The lower final cell density and faster cell density decrease rate of C. acetobutylicum ATCC 824 than those of C. acetobutylicum lyc::int(72 indicates that CA_C0554 was an important but not the sole autolysin-coding gene responding for the large-scale autolysis. Similar glucose utilization and solvents production but obvious lower cell density of C. acetobutylicum ATCC 824 comparing to C. acetobutylicum lyc::int(72 suggests that lysed C. acetobutylicum ATCC 824 cells were metabolic inactive. On the contrary, the spore density of C. acetobutylicum ATCC 824 is 26.1% higher than that of C. acetobutylicum lyc::int(72 in the final culture broth of batch fermentation. We speculated that spontaneous autolysis of metabolic-inactive cells provided nutrients for the sporulating cells. The present study suggests that one important biological role of spontaneous large-scale autolysis in C. acetobutylicum ATCC 824 batch fermentation is contributing to generation of more spores during sporulation.

  19. Spontaneous large-scale autolysis in Clostridium acetobutylicum contributes to generation of more spores.

    Science.gov (United States)

    Liu, Zhen; Qiao, Kai; Tian, Lei; Zhang, Quan; Liu, Zi-Yong; Li, Fu-Li

    2015-01-01

    Autolysis is a widespread phenomenon in bacteria. In batch fermentation of Clostridium acetobutylicum ATCC 824, there is a spontaneous large-scale autolysis phenomenon with significant decrease of cell density immediately after exponential phase. To unravel the role of autolysis, an autolysin-coding gene, CA_C0554, was disrupted by using ClosTron system to obtain the mutant C. acetobutylicum lyc::int(72). The lower final cell density and faster cell density decrease rate of C. acetobutylicum ATCC 824 than those of C. acetobutylicum lyc::int(72) indicates that CA_C0554 was an important but not the sole autolysin-coding gene responding for the large-scale autolysis. Similar glucose utilization and solvents production but obvious lower cell density of C. acetobutylicum ATCC 824 comparing to C. acetobutylicum lyc::int(72) suggests that lysed C. acetobutylicum ATCC 824 cells were metabolic inactive. On the contrary, the spore density of C. acetobutylicum ATCC 824 is 26.1% higher than that of C. acetobutylicum lyc::int(72) in the final culture broth of batch fermentation. We speculated that spontaneous autolysis of metabolic-inactive cells provided nutrients for the sporulating cells. The present study suggests that one important biological role of spontaneous large-scale autolysis in C. acetobutylicum ATCC 824 batch fermentation is contributing to generation of more spores during sporulation.

  20. Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses.

    Science.gov (United States)

    Liu, Bo; Madduri, Ravi K; Sotomayor, Borja; Chard, Kyle; Lacinski, Lukasz; Dave, Utpal J; Li, Jianqiang; Liu, Chunchen; Foster, Ian T

    2014-06-01

    Due to the upcoming data deluge of genome data, the need for storing and processing large-scale genome data, easy access to biomedical analyses tools, efficient data sharing and retrieval has presented significant challenges. The variability in data volume results in variable computing and storage requirements, therefore biomedical researchers are pursuing more reliable, dynamic and convenient methods for conducting sequencing analyses. This paper proposes a Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses, which enables reliable and highly scalable execution of sequencing analyses workflows in a fully automated manner. Our platform extends the existing Galaxy workflow system by adding data management capabilities for transferring large quantities of data efficiently and reliably (via Globus Transfer), domain-specific analyses tools preconfigured for immediate use by researchers (via user-specific tools integration), automatic deployment on Cloud for on-demand resource allocation and pay-as-you-go pricing (via Globus Provision), a Cloud provisioning tool for auto-scaling (via HTCondor scheduler), and the support for validating the correctness of workflows (via semantic verification tools). Two bioinformatics workflow use cases as well as performance evaluation are presented to validate the feasibility of the proposed approach. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Unscheduled load flow effect due to large variation in the distributed generation in a subtransmission network

    Science.gov (United States)

    Islam, Mujahidul

    A sustainable energy delivery infrastructure implies the safe and reliable accommodation of large scale penetration of renewable sources in the power grid. In this dissertation it is assumed there will be no significant change in the power transmission and distribution structure currently in place; except in the operating strategy and regulatory policy. That is to say, with the same old structure, the path towards unveiling a high penetration of switching power converters in the power system will be challenging. Some of the dimensions of this challenge are power quality degradation, frequent false trips due to power system imbalance, and losses due to a large neutral current. The ultimate result is the reduced life of many power distribution components - transformers, switches and sophisticated loads. Numerous ancillary services are being developed and offered by the utility operators to mitigate these problems. These services will likely raise the system's operational cost, not only from the utility operators' end, but also reflected on the Independent System Operators and by the Regional Transmission Operators (RTO) due to an unforeseen backlash of frequent variation in the load-side generation or distributed generation. The North American transmission grid is an interconnected system similar to a large electrical circuit. This circuit was not planned but designed over 100 years. The natural laws of physics govern the power flow among loads and generators except where control mechanisms are installed. The control mechanism has not matured enough to withstand the high penetration of variable generators at uncontrolled distribution ends. Unlike a radial distribution system, mesh or loop networks can alleviate complex channels for real and reactive power flow. Significant variation in real power injection and absorption on the distribution side can emerge as a bias signal on the routing reactive power in some physical links or channels that are not distinguishable

  2. Some problems raised by the operation of large nuclear turbo-generator sets. Automatic control system for steam turbo-generator units

    International Nuclear Information System (INIS)

    Cecconi, F.

    1976-01-01

    The design of an appropriate automatic system was found to be useful to improve the control of large size turbo-generator units so as to provide easy and efficient control and monitoring. The experience of the manufacturer of these turbo-generator units allowed a system well suited for this function to be designed [fr

  3. Next-Generation Microshutter Arrays for Large-Format Imaging and Spectroscopy

    Science.gov (United States)

    Moseley, Samuel; Kutyrev, Alexander; Brown, Ari; Li, Mary

    2012-01-01

    A next-generation microshutter array, LArge Microshutter Array (LAMA), was developed as a multi-object field selector. LAMA consists of small-scaled microshutter arrays that can be combined to form large-scale microshutter array mosaics. Microshutter actuation is accomplished via electrostatic attraction between the shutter and a counter electrode, and 2D addressing can be accomplished by applying an electrostatic potential between a row of shutters and a column, orthogonal to the row, of counter electrodes. Microelectromechanical system (MEMS) technology is used to fabricate the microshutter arrays. The main feature of the microshutter device is to use a set of standard surface micromachining processes for device fabrication. Electrostatic actuation is used to eliminate the need for macromechanical magnet actuating components. A simplified electrostatic actuation with no macro components (e.g. moving magnets) required for actuation and latching of the shutters will make the microshutter arrays robust and less prone to mechanical failure. Smaller-size individual arrays will help to increase the yield and thus reduce the cost and improve robustness of the fabrication process. Reducing the size of the individual shutter array to about one square inch and building the large-scale mosaics by tiling these smaller-size arrays would further help to reduce the cost of the device due to the higher yield of smaller devices. The LAMA development is based on prior experience acquired while developing microshutter arrays for the James Webb Space Telescope (JWST), but it will have different features. The LAMA modular design permits large-format mosaicking to cover a field of view at least 50 times larger than JWST MSA. The LAMA electrostatic, instead of magnetic, actuation enables operation cycles at least 100 times faster and a mass significantly smaller compared to JWST MSA. Also, standard surface micromachining technology will simplify the fabrication process, increasing

  4. Magnetic storm generation by large-scale complex structure Sheath/ICME

    Science.gov (United States)

    Grigorenko, E. E.; Yermolaev, Y. I.; Lodkina, I. G.; Yermolaev, M. Y.; Riazantseva, M.; Borodkova, N. L.

    2017-12-01

    We study temporal profiles of interplanetary plasma and magnetic field parameters as well as magnetospheric indices. We use our catalog of large-scale solar wind phenomena for 1976-2000 interval (see the catalog for 1976-2016 in web-side ftp://ftp.iki.rssi.ru/pub/omni/ prepared on basis of OMNI database (Yermolaev et al., 2009)) and the double superposed epoch analysis method (Yermolaev et al., 2010). Our analysis showed (Yermolaev et al., 2015) that average profiles of Dst and Dst* indices decrease in Sheath interval (magnetic storm activity increases) and increase in ICME interval. This profile coincides with inverted distribution of storm numbers in both intervals (Yermolaev et al., 2017). This behavior is explained by following reasons. (1) IMF magnitude in Sheath is higher than in Ejecta and closed to value in MC. (2) Sheath has 1.5 higher efficiency of storm generation than ICME (Nikolaeva et al., 2015). The most part of so-called CME-induced storms are really Sheath-induced storms and this fact should be taken into account during Space Weather prediction. The work was in part supported by the Russian Science Foundation, grant 16-12-10062. References. 1. Nikolaeva N.S., Y. I. Yermolaev and I. G. Lodkina (2015), Modeling of the corrected Dst* index temporal profile on the main phase of the magnetic storms generated by different types of solar wind, Cosmic Res., 53(2), 119-127 2. Yermolaev Yu. I., N. S. Nikolaeva, I. G. Lodkina and M. Yu. Yermolaev (2009), Catalog of Large-Scale Solar Wind Phenomena during 1976-2000, Cosmic Res., , 47(2), 81-94 3. Yermolaev, Y. I., N. S. Nikolaeva, I. G. Lodkina, and M. Y. Yermolaev (2010), Specific interplanetary conditions for CIR-induced, Sheath-induced, and ICME-induced geomagnetic storms obtained by double superposed epoch analysis, Ann. Geophys., 28, 2177-2186 4. Yermolaev Yu. I., I. G. Lodkina, N. S. Nikolaeva and M. Yu. Yermolaev (2015), Dynamics of large-scale solar wind streams obtained by the double superposed epoch

  5. Pressure transients resulting from sodium-water reaction following a large leak in LMFBR steam generator

    International Nuclear Information System (INIS)

    Rajput, A.K.

    1984-01-01

    The study of sodium water reaction, following a large leak, concerns primarily with the estimation of pressure/flow transients that are developed in the steam generator and the associated secondary circuit. This paper describes the mathematical formulations used in SWRT (Sodium Water Reaction Transients) code developed to estimate such pressure transients for FBTR plant. The results, obtained using SWRT have been presented for a leak in economiser (20m from bottom water header) and for a leak in super heater portions. A time lag of 50 m sec was considered for rupture disc takes to burst once the pressure experienced by it exceeds the set value. Also described in annexure to this paper is the mathematical formulation for two phase transient flow for the better estimation of leak rate from the ruptured end of the damaged heat transfer tube. This leak model considers slip but assumes thermal equilibrium between the liquid and vapour phases

  6. Application of CFB technology for large power generating units and CO2 capture

    International Nuclear Information System (INIS)

    Ryabov, G. A.; Folomeev, O. M.; Sankin, D. A.; Khaneev, K. V.; Bondarenko, I. G.; Mel'nikov, D. A.

    2010-01-01

    Data on the development of the circulating fluidized bed (CFB) technology for combustion of fuels in large power generating units are examined. The problems with raising the steam parameters and unit power of boilers with a circulating fluidized bed are examined. With the boiler system at the 460 MW unit at Lagisza (Poland) as an example, the feasibility of raising the efficiency of units with CFB boilers through deep recovery of the heat of the effluent gases and reducing expenditure for in-house needs is demonstrated. Comparative estimates of the capital and operating costs of 225 and 330 MW units are used to determine the conditions for optimum use of CFB boilers in the engineering renovation of thermal power plants in Russia. New areas for the application of CFB technology in CO 2 capture are analyzed in connection with the problem of reducing greenhouse gas emissions.

  7. Scott Correction for Large Atoms and Molecules in a Self-Generated Magnetic Field

    DEFF Research Database (Denmark)

    Erdös, Laszlo; Fournais, Søren; Solovej, Jan Philip

    2012-01-01

    constant. We show that, in the simultaneous limit $Z\\to\\infty$, $\\al\\to 0$ such that $\\kappa =Z\\al^2$ is fixed, the ground state energy of the system is given by a two term expansion $c_1Z^{7/3} + c_2(\\kappa) Z^2 + o(Z^2)$. The leading term is given by the non-magnetic Thomas-Fermi theory. Our result shows......We consider a large neutral molecule with total nuclear charge $Z$ in non-relativistic quantum mechanics with a self-generated classical electromagnetic field. To ensure stability, we assume that $Z\\al^2\\le \\kappa_0$ for a sufficiently small $\\kappa_0$, where $\\al$ denotes the fine structure...... that the magnetic field affects only the second (so-called Scott) term in the expansion....

  8. Report of preliminary investigations on the next-generation large-scale synchrotron radiation facility projects

    International Nuclear Information System (INIS)

    1990-01-01

    The Special Committee for Future Project of the Japanese Society for Synchrotron Radiation Research investigated the construction-projects of the large-scaled synchrotron radiation facilities which are presently in progress in Japan. As a result, the following both projects are considered the very valuable research-project which will carry the development of Japan's next-generation synchrotron radiation science: 1. the 8 GeV synchrotron radiation facilities (SPring-8) projected to be constructed by Japan Atomic Energy Research Institute and the Institute of Physical and Chemical Research under the sponsorship of Science Technology Agency at Harima Science Park City, Hyogo Pref., Japan. 2. The project to utilize the Tristan Main Ring (MR) of the National Laboratory for High Energy Physics as the radiation source. Both projects are unique in research theme and technological approach, and complemental each other. Therefore it has been concluded that both projects should be aided and ratified by the Society. (M.T.)

  9. EIRP Characterization of Electrically Large Wireless Equipment with Integrated Signal Generator in a Compact Environment

    Directory of Open Access Journals (Sweden)

    Soon-Soo Oh

    2015-01-01

    Full Text Available We describe a measurement technique to characterize the equivalent isotropically radiated power (EIRP of electrically large wireless equipment in a compact environment. A modified phase-measurement method was proposed and, thus, the separation of the signal generator and radiating element was not required during the measurement. A Fresnel-to-far-field transformation was used for the fast measurement time in a compact anechoic chamber. An experimental verification of the method was carried out in a compact anechoic chamber, where the source-detector separation was approximately 1/5 of the far-field distance. The measured magnitude and phase pattern exhibited only a small error. The EIRP obtained using a Fresnel-to-far-field transformation was compared with a reference value, and the error was within 0.5 dB.

  10. Solving Large Scale Nonlinear Eigenvalue Problem in Next-Generation Accelerator Design

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Ben-Shan; Bai, Zhaojun; /UC, Davis; Lee, Lie-Quan; Ko, Kwok; /SLAC

    2006-09-28

    A number of numerical methods, including inverse iteration, method of successive linear problem and nonlinear Arnoldi algorithm, are studied in this paper to solve a large scale nonlinear eigenvalue problem arising from finite element analysis of resonant frequencies and external Q{sub e} values of a waveguide loaded cavity in the next-generation accelerator design. They present a nonlinear Rayleigh-Ritz iterative projection algorithm, NRRIT in short and demonstrate that it is the most promising approach for a model scale cavity design. The NRRIT algorithm is an extension of the nonlinear Arnoldi algorithm due to Voss. Computational challenges of solving such a nonlinear eigenvalue problem for a full scale cavity design are outlined.

  11. Large eddy simulation of the generation and breakdown of a tumbling flow

    International Nuclear Information System (INIS)

    Toledo, Mauricio S.; Le Penven, Lionel; Buffat, Marc; Cadiou, Anne; Padilla, Judith

    2007-01-01

    Large eddy simulations (LES) are performed in order to reproduce the generation and the breakdown of a tumbling motion in the simplified model engine [Boree, J., Maurel, S., Bazile, R., 2002. Disruption of a compressed vortex. Phys. Fluids, 14 (7) 2543-2556]. A second-order accurate numerical scheme is applied in conjunction with a mixed finite volume/finite element formulation adapted for unstructured deforming meshes. Subgrid terms are kept as simple as possible with a Smagorinsky model in order to build a methodology devoted to engine-like flows. The main statistical quantities, such as mean velocity and turbulent kinetic energy, are obtained from a set of independent cycles and compared to experiments. Important experimental features, such as oscillations of the intake jet, vortex precession and a turbulent kinetic energy peak near the vortex core, are well reproduced

  12. CG2Real: Improving the Realism of Computer Generated Images Using a Large Collection of Photographs.

    Science.gov (United States)

    Johnson, Micah K; Dale, Kevin; Avidan, Shai; Pfister, Hanspeter; Freeman, William T; Matusik, Wojciech

    2011-09-01

    Computer-generated (CG) images have achieved high levels of realism. This realism, however, comes at the cost of long and expensive manual modeling, and often humans can still distinguish between CG and real images. We introduce a new data-driven approach for rendering realistic imagery that uses a large collection of photographs gathered from online repositories. Given a CG image, we retrieve a small number of real images with similar global structure. We identify corresponding regions between the CG and real images using a mean-shift cosegmentation algorithm. The user can then automatically transfer color, tone, and texture from matching regions to the CG image. Our system only uses image processing operations and does not require a 3D model of the scene, making it fast and easy to integrate into digital content creation workflows. Results of a user study show that our hybrid images appear more realistic than the originals.

  13. Performance of automatic generation control mechanisms with large-scale wind power

    Energy Technology Data Exchange (ETDEWEB)

    Ummels, B.C.; Gibescu, M.; Paap, G.C. [Delft Univ. of Technology (Netherlands); Kling, W.L. [Transmission Operations Department of TenneT bv (Netherlands)

    2007-11-15

    The unpredictability and variability of wind power increasingly challenges real-time balancing of supply and demand in electric power systems. In liberalised markets, balancing is a responsibility jointly held by the TSO (real-time power balancing) and PRPs (energy programs). In this paper, a procedure is developed for the simulation of power system balancing and the assessment of AGC performance in the presence of large-scale wind power, using the Dutch control zone as a case study. The simulation results show that the performance of existing AGC-mechanisms is adequate for keeping ACE within acceptable bounds. At higher wind power penetrations, however, the capabilities of the generation mix are increasingly challenged and additional reserves are required at the same level. (au)

  14. Generating functional analysis of complex formation and dissociation in large protein interaction networks

    International Nuclear Information System (INIS)

    Coolen, A C C; Rabello, S

    2009-01-01

    We analyze large systems of interacting proteins, using techniques from the non-equilibrium statistical mechanics of disordered many-particle systems. Apart from protein production and removal, the most relevant microscopic processes in the proteome are complex formation and dissociation, and the microscopic degrees of freedom are the evolving concentrations of unbound proteins (in multiple post-translational states) and of protein complexes. Here we only include dimer-complexes, for mathematical simplicity, and we draw the network that describes which proteins are reaction partners from an ensemble of random graphs with an arbitrary degree distribution. We show how generating functional analysis methods can be used successfully to derive closed equations for dynamical order parameters, representing an exact macroscopic description of the complex formation and dissociation dynamics in the infinite system limit. We end this paper with a discussion of the possible routes towards solving the nontrivial order parameter equations, either exactly (in specific limits) or approximately.

  15. The next generation balloon-borne large aperture submillimeter telescope (BLAST-TNG)

    Science.gov (United States)

    Dober, Bradley Jerald

    Large areas of astrophysics, such as precision cosmology, have benefited greatly from large maps and datasets, yielded by telescopes of ever-increasing number and ability. However, due to the unique challenges posed by submillimeter polarimetry, the study of molecular cloud dynamics and star formation remain stunted. Previously, polarimetry data was limited to a few vectors on only the brightest areas of molecular clouds. This made drawing statistically-driven conclusions a daunting task. However, the successful flight of the Balloon-born Large Aperture Submillimeter Telescope for Polarimetry (BLASTPol) generated maps with thousands of independent polarization measurements of molecular clouds, and ushered in a new era of empirical modeling of molecular cloud dynamics. Now that the potential benefits from large-scale maps of magnetic fields in molecular clouds had been identified, a successor that would truly unlock the secrets must be born. The Next Generation Balloon-borne Large Aperture Submillimeter Telescope (BLAST-TNG), the successor to BLASTPol, has the ability to make larger and more detailed maps of magnetic fields in molecular clouds. It will push the field of star formation into a statistics-driven, empirical realm. With these large, detailed datasets, astronomers will be able to find new relationships between the dust dynamics and the magnetic fields. The field will surge to a new level of understanding. One of the key enabling technologies of BLAST-TNG is its three arrays of polarization-sensitive Microwave Kinetic Inductance Detectors (MKIDs). MKIDs are superconducting RLC circuits with a resonant frequency that shifts proportionally to the amount of incident radiation. The key feature of MKIDs is that thousands of detectors, each with their own unique resonant frequency, can be coupled to the same readout line. This technology will be able to drive the production of large-scale monolithic arrays, containing tens or hundreds of thousands of detectors

  16. Flow-induced vibration analysis of a helical coil steam generator experiment using large eddy simulation

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Haomin; Solberg, Jerome; Merzari, Elia; Kraus, Adam; Grindeanu, Iulian

    2017-10-01

    This paper describes a numerical study of flow-induced vibration in a helical coil steam generator experiment conducted at Argonne National Laboratory in the 1980s. In the experiment, a half-scale sector model of a steam generator helical coil tube bank was subjected to still and flowing air and water, and the vibrational characteristics were recorded. The research detailed in this document utilizes the multi-physics simulation toolkit SHARP developed at Argonne National Laboratory, in cooperation with Lawrence Livermore National Laboratory, to simulate the experiment. SHARP uses the spectral element code Nek5000 for fluid dynamics analysis and the finite element code DIABLO for structural analysis. The flow around the coil tubes is modeled in Nek5000 by using a large eddy simulation turbulence model. Transient pressure data on the tube surfaces is sampled and transferred to DIABLO for the structural simulation. The structural response is simulated in DIABLO via an implicit time-marching algorithm and a combination of continuum elements and structural shells. Tube vibration data (acceleration and frequency) are sampled and compared with the experimental data. Currently, only one-way coupling is used, which means that pressure loads from the fluid simulation are transferred to the structural simulation but the resulting structural displacements are not fed back to the fluid simulation

  17. Improving large class performance and engagement through student-generated question banks.

    Science.gov (United States)

    Hancock, Dale; Hare, Nicole; Denny, Paul; Denyer, Gareth

    2018-03-12

    Disciplines such as Biochemistry and Molecular Biology, which involve concepts not included in the high-school curriculum, are very challenging for many first year university students. These subjects are particularly difficult for students accustomed to surface learning strategies involving memorization and recall of facts, as a deeper understanding of the relationship between concepts is needed for successful transfer to related areas and subsequent study. In this article, we explore an activity in a very large first year Molecular Biology course, in which students create multiple-choice questions related to targeted learning outcomes, and then answer and evaluate one another's questions. This activity encompasses elements of both self- and peer-assessment and the generative tasks of creating questions and producing written feedback may contribute to a deeper understanding of the material. We make use of a free online platform to facilitate all aspects of the process and analyze the effect of student engagement with the task on overall course performance. When compared to previous semester's cohorts, we observe a pronounced improvement in class performance on exam questions targeting similar concepts to the student-generated questions. In addition, those students that engage to a greater extent with the activity perform significantly better on the targeted exam questions than those who are less active, yet all students perform similarly on a set of isolated control questions appearing on the same exam. © 2018 by The International Union of Biochemistry and Molecular Biology, 2018. © 2018 The International Union of Biochemistry and Molecular Biology.

  18. Effects of induced magnetic field on large scale pulsed MHD generator with two phase flow

    International Nuclear Information System (INIS)

    Ishikawa, M.; Koshiba, Y.; Matsushita, T.

    2004-01-01

    A large pulsed MHD generator 'SAKHALIN' was constructed in Russia (the former Soviet-Union) and operated with solid fuels. The 'SAKHALIN' with the channel length of 4.5 m could demonstrate the electric power output of 510 MW. The effects of induced magnetic field and two phase flow on the shock wave within the 'SAKHALIN' generator have been studied by time dependent, one dimensional analyses. It has been shown that the magnetic Reynolds number is about 0.58 for Run No. 1, and the induced magnetic flux density is about 20% at the entrance and exit of the MHD channel. The shock wave becomes stronger when the induced magnetic field is taken into account, when the operation voltage becomes low. The working gas plasma contains about 40% of liquid particles (Al 2 O 3 ) in weight, and the present analysis treats the liquid particles as another gas. In the case of mono-phase flow, the sharp shock wave is induced when the load voltage becomes small such as 500 V with larger Lorentz force, whereas in the case of two phase flow, the shock wave becomes less sharp because of the interaction with liquid particles

  19. Rucio – The next generation of large scale distributed system for ATLAS data management

    International Nuclear Information System (INIS)

    Garonne, V; Vigne, R; Stewart, G; Barisits, M; Eermann, T B; Lassnig, M; Serfon, C; Goossens, L; Nairz, A

    2014-01-01

    Rucio is the next-generation Distributed Data Management (DDM) system benefiting from recent advances in cloud and 'Big Data' computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 140 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will deal with these issues by relying on a conceptual data model and new technology to ensure system scalability, address new user requirements and employ new automation framework to reduce operational overheads. We present the key concepts of Rucio, including its data organization/representation and a model of how to manage central group and user activities. The Rucio design, and the technology it employs, is described, specifically looking at its RESTful architecture and the various software components it uses. We show also the performance of the system.

  20. Rucio - The next generation of large scale distributed system for ATLAS Data Management

    Science.gov (United States)

    Garonne, V.; Vigne, R.; Stewart, G.; Barisits, M.; eermann, T. B.; Lassnig, M.; Serfon, C.; Goossens, L.; Nairz, A.; Atlas Collaboration

    2014-06-01

    Rucio is the next-generation Distributed Data Management (DDM) system benefiting from recent advances in cloud and "Big Data" computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 140 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will deal with these issues by relying on a conceptual data model and new technology to ensure system scalability, address new user requirements and employ new automation framework to reduce operational overheads. We present the key concepts of Rucio, including its data organization/representation and a model of how to manage central group and user activities. The Rucio design, and the technology it employs, is described, specifically looking at its RESTful architecture and the various software components it uses. We show also the performance of the system.

  1. Algebraic mesh generation for large scale viscous-compressible aerodynamic simulation

    International Nuclear Information System (INIS)

    Smith, R.E.

    1984-01-01

    Viscous-compressible aerodynamic simulation is the numerical solution of the compressible Navier-Stokes equations and associated boundary conditions. Boundary-fitted coordinate systems are well suited for the application of finite difference techniques to the Navier-Stokes equations. An algebraic approach to boundary-fitted coordinate systems is one where an explicit functional relation describes a mesh on which a solution is obtained. This approach has the advantage of rapid-precise mesh control. The basic mathematical structure of three algebraic mesh generation techniques is described. They are transfinite interpolation, the multi-surface method, and the two-boundary technique. The Navier-Stokes equations are transformed to a computational coordinate system where boundary-fitted coordinates can be applied. Large-scale computation implies that there is a large number of mesh points in the coordinate system. Computation of viscous compressible flow using boundary-fitted coordinate systems and the application of this computational philosophy on a vector computer are presented

  2. Rucio - The next generation of large scale distributed system for ATLAS Data Management

    CERN Document Server

    Garonne, V; The ATLAS collaboration; Beermann, T; Goossens, L; Lassnig, M; Nairz, A; Stewart, GA; Vigne, V; Serfon, C

    2013-01-01

    Rucio is the next-generation Distributed Data Management(DDM) system benefiting from recent advances in cloud and "Big Data" computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 140 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will address these issues by relying on a conceptual data model and new technology to ensure system scalability, address new user requirements and employ new automation framework to reduce operational overheads. We present the key concepts of Rucio, including its data organization/representation and a model of how ATLAS central group and user activities will be managed. The Rucio design, and the technology it employs, is described...

  3. Rucio - The next generation of large scale distributed system for ATLAS Data Management

    CERN Document Server

    Garonne, V; The ATLAS collaboration; Beermann, T; Goossens, L; Lassnig, M; Nairz, A; Stewart, GA; Vigne, V; Serfon, C

    2014-01-01

    Rucio is the next-generation Distributed Data Management(DDM) system benefiting from recent advances in cloud and ”Big Data” computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 140 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio will address these issues by relying on a conceptual data model and new technology to ensure system scalability, address new user requirements and employ new automation framework to reduce operational overheads. We present the key concepts of Rucio, including its data organization/representation and a model of how ATLAS central group and user activities will be managed. The Rucio design, and the technology it employs, is descr...

  4. Generating descriptive visual words and visual phrases for large-scale image applications.

    Science.gov (United States)

    Zhang, Shiliang; Tian, Qi; Hua, Gang; Huang, Qingming; Gao, Wen

    2011-09-01

    Bag-of-visual Words (BoWs) representation has been applied for various problems in the fields of multimedia and computer vision. The basic idea is to represent images as visual documents composed of repeatable and distinctive visual elements, which are comparable to the text words. Notwithstanding its great success and wide adoption, visual vocabulary created from single-image local descriptors is often shown to be not as effective as desired. In this paper, descriptive visual words (DVWs) and descriptive visual phrases (DVPs) are proposed as the visual correspondences to text words and phrases, where visual phrases refer to the frequently co-occurring visual word pairs. Since images are the carriers of visual objects and scenes, a descriptive visual element set can be composed by the visual words and their combinations which are effective in representing certain visual objects or scenes. Based on this idea, a general framework is proposed for generating DVWs and DVPs for image applications. In a large-scale image database containing 1506 object and scene categories, the visual words and visual word pairs descriptive to certain objects or scenes are identified and collected as the DVWs and DVPs. Experiments show that the DVWs and DVPs are informative and descriptive and, thus, are more comparable with the text words than the classic visual words. We apply the identified DVWs and DVPs in several applications including large-scale near-duplicated image retrieval, image search re-ranking, and object recognition. The combination of DVW and DVP performs better than the state of the art in large-scale near-duplicated image retrieval in terms of accuracy, efficiency and memory consumption. The proposed image search re-ranking algorithm: DWPRank outperforms the state-of-the-art algorithm by 12.4% in mean average precision and about 11 times faster in efficiency.

  5. Some problems raised by the operation of large nuclear turbo-generator sets. Solutions proposed for the protection of large size generators

    International Nuclear Information System (INIS)

    Chaumienne, J.-P.

    1976-01-01

    The operating requirements of nuclear power stations call for relays with ever increasing performances. This urges the development of new electronic systems while giving high importance to their reliability. So as to provide for easy application and minitoring of the relays, even when the turbo-generator unit is operating, a new cubicle design is considered which offers maximum safety and flexibility in use [fr

  6. Modification of input datasets for the Ensemble Streamflow Prediction based on large scale climatic indices and weather generator

    Czech Academy of Sciences Publication Activity Database

    Šípek, Václav; Daňhelka, J.

    2015-01-01

    Roč. 528, September (2015), s. 720-733 ISSN 0022-1694 Institutional support: RVO:67985874 Keywords : seasonal forecasting * ESP * large-scale climate * weather generator Subject RIV: DA - Hydrology ; Limnology Impact factor: 3.043, year: 2015

  7. Resolution 8.069/12. It approve the regulations for the large size structures installation, destined for wind power generation

    International Nuclear Information System (INIS)

    2012-01-01

    This resolution approve the regulations for the large size structures installation, destined to wind power generation. The objective of this rule is to regulate the urban conditions of the facilities and the environmental guarantees, safety and inhabitants wholesomeness

  8. Generation of large-scale vorticity in rotating stratified turbulence with inhomogeneous helicity: mean-field theory

    Science.gov (United States)

    Kleeorin, N.

    2018-06-01

    We discuss a mean-field theory of the generation of large-scale vorticity in a rotating density stratified developed turbulence with inhomogeneous kinetic helicity. We show that the large-scale non-uniform flow is produced due to either a combined action of a density stratified rotating turbulence and uniform kinetic helicity or a combined effect of a rotating incompressible turbulence and inhomogeneous kinetic helicity. These effects result in the formation of a large-scale shear, and in turn its interaction with the small-scale turbulence causes an excitation of the large-scale instability (known as a vorticity dynamo) due to a combined effect of the large-scale shear and Reynolds stress-induced generation of the mean vorticity. The latter is due to the effect of large-scale shear on the Reynolds stress. A fast rotation suppresses this large-scale instability.

  9. Self-Tuning Linear Quadratic Supervisory Regulation of a Diesel Generator using Large-Signal State Estimation

    DEFF Research Database (Denmark)

    Knudsen, Jesper Viese; Bendtsen, Jan Dimon; Andersen, Palle

    2016-01-01

    In this paper, a self-tuning linear quadratic supervisory regulator using a large-signal state estimator for a diesel driven generator set is proposed. The regulator improves operational efficiency, in comparison to current implementations, by (i) automating the initial tuning process and (ii...... throughout the operating range of the diesel generator....

  10. KINETIC ALFVÉN WAVE GENERATION BY LARGE-SCALE PHASE MIXING

    International Nuclear Information System (INIS)

    Vásconez, C. L.; Pucci, F.; Valentini, F.; Servidio, S.; Malara, F.; Matthaeus, W. H.

    2015-01-01

    One view of the solar wind turbulence is that the observed highly anisotropic fluctuations at spatial scales near the proton inertial length d p may be considered as kinetic Alfvén waves (KAWs). In the present paper, we show how phase mixing of large-scale parallel-propagating Alfvén waves is an efficient mechanism for the production of KAWs at wavelengths close to d p and at a large propagation angle with respect to the magnetic field. Magnetohydrodynamic (MHD), Hall magnetohydrodynamic (HMHD), and hybrid Vlasov–Maxwell (HVM) simulations modeling the propagation of Alfvén waves in inhomogeneous plasmas are performed. In the linear regime, the role of dispersive effects is singled out by comparing MHD and HMHD results. Fluctuations produced by phase mixing are identified as KAWs through a comparison of polarization of magnetic fluctuations and wave-group velocity with analytical linear predictions. In the nonlinear regime, a comparison of HMHD and HVM simulations allows us to point out the role of kinetic effects in shaping the proton-distribution function. We observe the generation of temperature anisotropy with respect to the local magnetic field and the production of field-aligned beams. The regions where the proton-distribution function highly departs from thermal equilibrium are located inside the shear layers, where the KAWs are excited, this suggesting that the distortions of the proton distribution are driven by a resonant interaction of protons with KAW fluctuations. Our results are relevant in configurations where magnetic-field inhomogeneities are present, as, for example, in the solar corona, where the presence of Alfvén waves has been ascertained

  11. Frontiers of Radio Astronomy in the 2020s: The Next Generation Very Large Array

    Science.gov (United States)

    Murphy, Eric Joseph; ngVLA Project Office, ngVLA Science and Technical Advisory Councils, ngVLA Science Working Groups

    2018-01-01

    This talk will describe the current community-driven science goals, design, and planning status of a future large centimeter radio array: the ‘Next Generation Very Large Array’ (ngVLA). The ngVLA is being developed to observe at wavelengths between ALMA at submm wavelengths, and the future SKA-1 at few centimeter and longer wavelengths, opening a new window on the Universe through ultra-sensitive imaging of thermal line and continuum emission down to milliarcsecond resolution, and unprecedented broad band continuum polarimetric imaging of non-thermal processes. The current design for the array includes 10x more effective collecting area and 10x higher spatial resolution than the current JVLA or ALMA, carefully optimized for operation in the frequency range 10GHz to 50GHz, while still delivering world-leading sensitivity over the entire 1.2GHz to 116 GHz spectrum.With this array, new frontiers in modern astronomy can be reached, including direct imaging and chemical analysis of planet formation in the terrestrial-zone of nearby stars, studies of dust-obscured star formation and the cosmic baryon cycle down to pc-scales in the local Universe, and detailed imaging of molecular gas and galaxy formation into the epoch of reionization. Novel techniques for exploring temporal phenomena on timescales from milliseconds to years will also be implemented. The ngVLA will be situated in the desert southwest of the United States, centered on the current JVLA infrastructure, with multiple antennas anticipated in states/regions adjacent to NM, and in northern Mexico.A recently formed Project Office is working closely with the U.S. and international research community to design the array, and plan its construction beginning mid next decade. Recent significant funding for design and development brought forward by the NSF will enable detailed science case development and technology prototyping/risk reduction before the next U.S astronomy Decadal Survey.

  12. KINETIC ALFVÉN WAVE GENERATION BY LARGE-SCALE PHASE MIXING

    Energy Technology Data Exchange (ETDEWEB)

    Vásconez, C. L.; Pucci, F.; Valentini, F.; Servidio, S.; Malara, F. [Dipartimento di Fisica, Università della Calabria, I-87036, Rende (CS) (Italy); Matthaeus, W. H. [Department of Physics and Astronomy, University of Delaware, DE 19716 (United States)

    2015-12-10

    One view of the solar wind turbulence is that the observed highly anisotropic fluctuations at spatial scales near the proton inertial length d{sub p} may be considered as kinetic Alfvén waves (KAWs). In the present paper, we show how phase mixing of large-scale parallel-propagating Alfvén waves is an efficient mechanism for the production of KAWs at wavelengths close to d{sub p} and at a large propagation angle with respect to the magnetic field. Magnetohydrodynamic (MHD), Hall magnetohydrodynamic (HMHD), and hybrid Vlasov–Maxwell (HVM) simulations modeling the propagation of Alfvén waves in inhomogeneous plasmas are performed. In the linear regime, the role of dispersive effects is singled out by comparing MHD and HMHD results. Fluctuations produced by phase mixing are identified as KAWs through a comparison of polarization of magnetic fluctuations and wave-group velocity with analytical linear predictions. In the nonlinear regime, a comparison of HMHD and HVM simulations allows us to point out the role of kinetic effects in shaping the proton-distribution function. We observe the generation of temperature anisotropy with respect to the local magnetic field and the production of field-aligned beams. The regions where the proton-distribution function highly departs from thermal equilibrium are located inside the shear layers, where the KAWs are excited, this suggesting that the distortions of the proton distribution are driven by a resonant interaction of protons with KAW fluctuations. Our results are relevant in configurations where magnetic-field inhomogeneities are present, as, for example, in the solar corona, where the presence of Alfvén waves has been ascertained.

  13. High-Efficiency, Multijunction Solar Cells for Large-Scale Solar Electricity Generation

    Science.gov (United States)

    Kurtz, Sarah

    2006-03-01

    A solar cell with an infinite number of materials (matched to the solar spectrum) has a theoretical efficiency limit of 68%. If sunlight is concentrated, this limit increases to about 87%. These theoretical limits are calculated using basic physics and are independent of the details of the materials. In practice, the challenge of achieving high efficiency depends on identifying materials that can effectively use the solar spectrum. Impressive progress has been made with the current efficiency record being 39%. Today's solar market is also showing impressive progress, but is still hindered by high prices. One strategy for reducing cost is to use lenses or mirrors to focus the light on small solar cells. In this case, the system cost is dominated by the cost of the relatively inexpensive optics. The value of the optics increases with the efficiency of the solar cell. Thus, a concentrator system made with 35%- 40%-efficient solar cells is expected to deliver 50% more power at a similar cost when compare with a system using 25%-efficient cells. Today's markets are showing an opportunity for large concentrator systems that didn't exist 5-10 years ago. Efficiencies may soon pass 40% and ultimately may reach 50%, providing a pathway to improved performance and decreased cost. Many companies are currently investigating this technology for large-scale electricity generation. The presentation will cover the basic physics and more practical considerations to achieving high efficiency as well as describing the current status of the concentrator industry. This work has been authored by an employee of the Midwest Research Institute under Contract No. DE- AC36-99GO10337 with the U.S. Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, worldwide license to publish or reproduce the published form of this work, or allow

  14. Applications of large-area nanopatterning to energy generation and storage devices

    Science.gov (United States)

    Mills, Eric N.

    This dissertation encompasses the creation and testing of nanostructured, electrochemically-active energy generation and storage devices, and development of the associated fabrication techniques. The fabricated devices include nanopatterned, plasmonically-active, TiO2+Au thin films for Photocatalytic Water Splitting (PCW), TiO2-based Dye-Sensitized Solar Cells (DSSCs) incorporating nanopatterned, plasmonically-active metallic front electrodes, and Si nanopillar anodes for Li-ion batteries. Techniques were also developed for encapsulation and removal of wet-etched Si nanowires from their mother substrates. TiO2 was the first material to be widely used for PCW. Its use is hampered by its large bandgap (~3.2eV), and poor recombination lifetimes. Au nanoparticles (NPs) have been previously used to improve recombination lifetimes in TiO2 by separating photogenerated carriers near the NP edges, and to increase photocurrents by injecting plasmonically-excited hot electrons into the TiO2 conduction band. Using nanostructured TiO 2+Au electrodes, we aim to increase the PCW efficiency of TiO2 -based electrodes. Dye-sensitized solar cells (DSSCs) employ visible-absorbing dyes anchored to a high-surface-area semiconducting scaffold. The front transparent conducting electrode (TCE) is typically ITO, a scarce and expensive material. We aim to increase the efficiency of thin-film DSSCs and eliminate the use of ITO by using a metallic subwavelength array (MESH) of nanoholes as the front TCE. Silicon holds promise as a high-capacity anode material for Li-ion batteries, as it can store ~10x the Li of graphite, the current leading anode material (3569 vs. 372 mAh/g). However, Si undergoes dramatic (>300%) volume expansion upon "lithiation", pulverizing any structure with non-nanoscopic dimensions (>250nm). We created large-area arrays of "nanopillars" with sub-100nm diameters, using roll-to-roll-compatible flexible-mold NIL on commercially-available metal substrates. Ordered

  15. Second-Generation Large Civil Tiltrotor 7- by 10-Foot Wind Tunnel Test Data Report

    Science.gov (United States)

    Theodore, Colin R.; Russell, Carl R.; Willink, Gina C.; Pete, Ashley E.; Adibi, Sierra A.; Ewert, Adam; Theuns, Lieselotte; Beierle, Connor

    2016-01-01

    An approximately 6-percent scale model of the NASA Second-Generation Large Civil Tiltrotor (LCTR2) Aircraft was tested in the U.S. Army 7- by 10-Foot Wind Tunnel at NASA Ames Research Center January 4 to April 19, 2012, and September 18 to November 1, 2013. The full model was tested, along with modified versions in order to determine the effects of the wing tip extensions and nacelles; the wing was also tested separately in the various configurations. In both cases, the wing and nacelles used were adopted from the U.S. Army High Efficiency Tilt Rotor (HETR) aircraft, in order to limit the cost of the experiment. The full airframe was tested in high-speed cruise and low-speed hover flight conditions, while the wing was tested only in cruise conditions, with Reynolds numbers ranging from 0 to 1.4 million. In all cases, the external scale system of the wind tunnel was used to collect data. Both models were mounted to the scale using two support struts attached underneath the wing; the full airframe model also used a third strut attached at the tail. The collected data provides insight into the performance of the preliminary design of the LCTR2 and will be used for computational fluid dynamics (CFD) validation and the development of flight dynamics simulation models.

  16. Electrical efficiency and renewable energy - Economical alternatives to large-scale power generation

    International Nuclear Information System (INIS)

    Oettli, B.; Hammer, S.; Moret, F.; Iten, R.; Nordmann, T.

    2010-05-01

    This final report for WWF Switzerland, Greenpeace Switzerland, the Swiss Energy Foundation SES, Pro Natura and the Swiss Cantons of Basel City and Geneva takes a look at the energy-relevant effects of the propositions made by Swiss electricity utilities for large-scale power generation. These proposals are compared with a strategy that proposes investments in energy-efficiency and the use of renewable sources of energy. The effects of both scenarios on the environment and the risks involved are discussed, as are the investments involved. The associated effects on the Swiss national economy are also discussed. For the efficiency and renewables scenario, two implementation variants are discussed: Inland investments and production are examined as are foreign production options and/or import from foreign countries. The methods used in the study are introduced and discussed. Investment and cost considerations, earnings and effects on employment are also reviewed. The report is completed with an extensive appendix which, amongst other things, includes potential reviews, cost estimates and a discussion on 'smart grids'

  17. Improved cost of energy comparison of permanent magnet generators for large offshore wind turbines

    NARCIS (Netherlands)

    Hart, K.; McDonald, A.; Polinder, H.; Corr, E.; Carroll, J.

    2014-01-01

    This paper investigates geared and direct-drive permanent magnet generators for a typical offshore wind turbine, providing a detailed comparison of various wind turbine drivetrain configurations in order to minimise the Cost of Energy. The permanent magnet generator topologies considered include a

  18. Large Hadron Collider at CERN: Beams generating high-energy-density matter.

    Science.gov (United States)

    Tahir, N A; Schmidt, R; Shutov, A; Lomonosov, I V; Piriz, A R; Hoffmann, D H H; Deutsch, C; Fortov, V E

    2009-04-01

    This paper presents numerical simulations that have been carried out to study the thermodynamic and hydrodynamic responses of a solid copper cylindrical target that is facially irradiated along the axis by one of the two Large Hadron Collider (LHC) 7 TeV/ c proton beams. The energy deposition by protons in solid copper has been calculated using an established particle interaction and Monte Carlo code, FLUKA, which is capable of simulating all components of the particle cascades in matter, up to multi-TeV energies. These data have been used as input to a sophisticated two-dimensional hydrodynamic computer code BIG2 that has been employed to study this problem. The prime purpose of these investigations was to assess the damage caused to the equipment if the entire LHC beam is lost at a single place. The FLUKA calculations show that the energy of protons will be deposited in solid copper within about 1 m assuming constant material parameters. Nevertheless, our hydrodynamic simulations have shown that the energy deposition region will extend to a length of about 35 m over the beam duration. This is due to the fact that first few tens of bunches deposit sufficient energy that leads to high pressure that generates an outgoing radial shock wave. Shock propagation leads to continuous reduction in the density at the target center that allows the protons delivered in subsequent bunches to penetrate deeper and deeper into the target. This phenomenon has also been seen in case of heavy-ion heated targets [N. A. Tahir, A. Kozyreva, P. Spiller, D. H. H. Hoffmann, and A. Shutov, Phys. Rev. E 63, 036407 (2001)]. This effect needs to be considered in the design of a sacrificial beam stopper. These simulations have also shown that the target is severely damaged and is converted into a huge sample of high-energy density (HED) matter. In fact, the inner part of the target is transformed into a strongly coupled plasma with fairly uniform physical conditions. This work, therefore, has

  19. Potential of Partially Superconducting Generators for Large Direct-Drive Wind Turbines

    DEFF Research Database (Denmark)

    Liu, Dong; Polinder, Henk; Abrahamsen, Asger Bech

    2017-01-01

    This paper aims at assessing the potential of partially superconducting generators for 10 MW direct-drive wind turbines by investigating their performance for a very wide range of excitation currents. Performance indicators such as shear stress and efficiency and other generator characteristics...... are compared for 12 different generator topologies. To be sufficiently attractive, superconducting generators must have significant advantages over permanent magnet direct-drive generators, which typically have shear stresses of the order of 53 kPa and efficiencies of 96%. Therefore, we investigate what...... they achieve this performance. By examining the maximum magnetic flux density at the location of the superconducting field winding, feasible superconductors can be chosen according to their engineering current density capabilities. It is found that high- and low-temperature superconductors can meet...

  20. Liquid metal fast breeder reactor steam generator survey of the consequences of large scale sodium water reaction

    International Nuclear Information System (INIS)

    Vambenepe, G.

    1978-01-01

    The ''Retona'' three-dimensional hydrodynamic computing code is being developed by Electricity de France to survey the consequences, on the very plant, of a large scale sodium water reaction in liquid metal steam generators. In this communication, the heat-exchanger geometry is schematized and the problem solving process briefly described under assumed simplifying hypotheses. The application of the results to the Creusot-Loire steam generator selected for Super-Phenix are given as an example. (author)

  1. Maximal Aerobic and Anaerobic Power Generation in Large Crocodiles versus Mammals: Implications for Dinosaur Gigantothermy

    OpenAIRE

    Seymour, Roger S.

    2013-01-01

    Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30?C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosau...

  2. Lewis Research Center studies of multiple large wind turbine generators on a utility network

    Science.gov (United States)

    Gilbert, L. J.; Triezenberg, D. M.

    1979-01-01

    A NASA-Lewis program to study the anticipated performance of a wind turbine generator farm on an electric utility network is surveyed. The paper describes the approach of the Lewis Wind Energy Project Office to developing analysis capabilities in the area of wind turbine generator-utility network computer simulations. Attention is given to areas such as, the Lewis Purdue hybrid simulation, an independent stability study, DOE multiunit plant study, and the WEST simulator. Also covered are the Lewis mod-2 simulation including analog simulation of a two wind turbine system and comparison with Boeing simulation results, and gust response of a two machine model. Finally future work to be done is noted and it is concluded that the study shows little interaction between the generators and between the generators and the bus.

  3. A Lightweight, Direct-Drive, Fully Superconducting Generator for Large Wind Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Meinke, Rainer [Advanced Magnet Lab, Palm Bay, FL (United States); Morrison, Darrell [Emerson Inc., St. Louis, MO (United States); Prince, Vernon Gregory [Advanced Magnet Lab, Palm Bay, FL (United States)

    2014-12-31

    The current trend in the offshore wind turbine industry favors direct-drive generators based on permanent magnets, as they allow for a simple and reliable drivetrain without a gearbox. These generators, however, do not scale very well to high power levels beneficial for offshore wind, and their use in wind turbines over 6 MW is questionable in terms of mass and economic feasibility. Moreover, rare earth materials composing the permanent magnets are becoming less available, more costly and potentially unavailable in the foreseeable future. A stated goal of the DOE is a critical materials strategy that pursues the development of substitute materials and technology for rare earth materials to improve supply chain flexibility and meet the needs of the clean energy economy.Therefore, alternative solutions are needed, in terms of both favorable up-scaling and minimizing or eliminating the use of permanent magnets. The generator design presented in this document addresses both these issues with the development of a fully superconducting generator (FSG) with unprecedented high specific torque. A full-scale, 10-MW, 10-rpm generator will weigh less about 150 metric tons, compared to 300 metric tons for an equivalent direct-drive, permanent magnet generator. The developed concept does not use any rare earth materials in its critical drive components, but rather relies on a superconductor composed of mainly magnesium and boron (MgB2), both of which are in abundant supply from multiple global sources.

  4. Modification of input datasets for the Ensemble Streamflow Prediction based on large scale climatic indices and weather generator

    Czech Academy of Sciences Publication Activity Database

    Šípek, Václav; Daňhelka, J.

    2015-01-01

    Roč. 528, September (2015), s. 720-733 ISSN 0022-1694 Institutional support: RVO:67985874 Keywords : sea sonal forecasting * ESP * large-scale climate * weather generator Subject RIV: DA - Hydrology ; Limnology Impact factor: 3.043, year: 2015

  5. Premixed and non-premixed generated manifolds in large-eddy simulation of Sandia flame D and F

    NARCIS (Netherlands)

    Vreman, A.W.; Albrecht, B.A.; Oijen, van J.A.; Goey, de L.P.H.; Bastiaans, R.J.M.

    2008-01-01

    Premixed and nonpremixed flamelet-generated manifolds have been constructed and applied to large-eddy simulation of the piloted partially premixed turbulent flames Sandia Flame D and F. In both manifolds the chemistry is parameterized as a function of the mixture fraction and a progress variable.

  6. Modeling and Control of Large Eddies Generated by Maneuvering Self-Propelled Bodies in Stratified Fluids

    National Research Council Canada - National Science Library

    Voropayev, Sergey

    2001-01-01

    .... It is also shown that for vertical background shear typical for the upper ocean, the shear itself only partly suppresses the eddy formation and reduces their decay times, which still remain significantly large...

  7. A synthetic-eddy-method for generating inflow conditions for large-eddy simulations

    International Nuclear Information System (INIS)

    Jarrin, N.; Benhamadouche, S.; Laurence, D.; Prosser, R.

    2006-01-01

    The generation of inflow data for spatially developing turbulent flows is one of the challenges that must be addressed prior to the application of LES to industrial flows and complex geometries. A new method of generation of synthetic turbulence, suitable for complex geometries and unstructured meshes, is presented herein. The method is based on the classical view of turbulence as a superposition of coherent structures. It is able to reproduce prescribed first and second order one point statistics, characteristic length and time scales, and the shape of coherent structures. The ability of the method to produce realistic inflow conditions in the test cases of a spatially decaying homogeneous isotropic turbulence and of a fully developed turbulent channel flow is presented. The method is systematically compared to other methods of generation of inflow conditions (precursor simulation, spectral methods and algebraic methods)

  8. Segmentation and fragmentation of melt jets due to generation of large-scale structures. Observation in low subcooling conditions

    International Nuclear Information System (INIS)

    Sugiyama, Ken-ichiro; Yamada, Tsuyoshi

    1999-01-01

    In order to clarify a mechanism of melt-jet breakup and fragmentation entirely different from the mechanism of stripping, a series of experiments were carried out by using molten tin jets of 100 grams with initial temperatures from 250degC to 900degC. Molten tin jets with a small kinematic viscosity and a large thermal diffusivity were used to observe breakup and fragmentation of melt jets enhanced thermally and hydrodynamically. We observed jet columns with second-stage large-scale structures generated by the coalescence of large-scale structures recognized in the field of fluid mechanics. At a greater depth, the segmentation of jet columns between second-stage large-scale structures and the fragmentation of the segmented jet columns were observed. It is reasonable to consider that the segmentation and the fragmentation of jet columns are caused by the boiling of water hydrodynamically entrained within second-stage large-scale structures. (author)

  9. Prospects for generating electricity by large onshore and offshore wind farms

    Science.gov (United States)

    Volker, Patrick J. H.; Hahmann, Andrea N.; Badger, Jake; Jørgensen, Hans E.

    2017-03-01

    The decarbonisation of energy sources requires additional investments in renewable technologies, including the installation of onshore and offshore wind farms. For wind energy to remain competitive, wind farms must continue to provide low-cost power even when covering larger areas. Inside very large wind farms, winds can decrease considerably from their free-stream values to a point where an equilibrium wind speed is reached. The magnitude of this equilibrium wind speed is primarily dependent on the balance between turbine drag force and the downward momentum influx from above the wind farm. We have simulated for neutral atmospheric conditions, the wind speed field inside different wind farms that range from small (25 km2) to very large (105 km2) in three regions with distinct wind speed and roughness conditions. Our results show that the power density of very large wind farms depends on the local free-stream wind speed, the surface characteristics, and the turbine density. In onshore regions with moderate winds the power density of very large wind farms reaches 1 W m-2, whereas in offshore regions with very strong winds it exceeds 3 W m-2. Despite a relatively low power density, onshore regions with moderate winds offer potential locations for very large wind farms. In offshore regions, clusters of smaller wind farms are generally preferable; under very strong winds also very large offshore wind farms become efficient.

  10. Interspecies chimeric complementation for the generation of functional human tissues and organs in large animal hosts.

    Science.gov (United States)

    Wu, Jun; Izpisua Belmonte, Juan Carlos

    2016-06-01

    The past decade's rapid progress in human pluripotent stem cell (hPSC) research has generated hope for meeting the rising demand of organ donation, which remains the only effective cure for end-stage organ failure, a major cause of death worldwide. Despite the potential, generation of transplantable organs from hPSCs using in vitro differentiation is far-fetched. An in vivo interspecies chimeric complementation strategy relying on chimeric-competent hPSCs and zygote genome editing provides an auspicious alternative for providing unlimited organ source for transplantation.

  11. Generation Expansion Planning with Large Amounts of Wind Power via Decision-Dependent Stochastic Programming

    DEFF Research Database (Denmark)

    Zhan, Yiduo; Zheng, Qipeng; Wang, Jianhui

    2016-01-01

    , the probability distribution function is determined by not only input parameters but also decision variables. To deal with the nonlinear constraints in our model, a quasi-exact solution approach is then introduced to reformulate the multistage stochastic investment model to a mixed-integer linear programming......Power generation expansion planning needs to deal with future uncertainties carefully, given that the invested generation assets will be in operation for a long time. Many stochastic programming models have been proposed to tackle this challenge. However, most previous works assume predetermined...

  12. Bismut's way of the Malliavin calculus for large order generators on a Lie group

    Science.gov (United States)

    Léandre, Rémi

    2018-01-01

    We adapt Bismut's mechanism of the Malliavin Calculus to right invariant big order generator on a Lie group. We use deeply the symmetry in order to avoid the use of the Malliavin matrix. As an application, we deduce logarithmic estimates in small time of the heat kernel.

  13. Ultraheavy Yukawa-bound states of fourth-generation at Large ...

    Indian Academy of Sciences (India)

    2012-10-05

    Oct 5, 2012 ... Abstract. A study of bound states of the fourth-generation quarks in the range of 500–700 GeV is presented, where the binding energies are expected to be mainly of Yukawa origin, with QCD subdominant. Near degeneracy of their masses exhibits a new 'isospin'. The production of a colour- octet, isosinglet ...

  14. Dual branch high voltage pulse generator for the beam extraction of the Large Hadron Collider

    CERN Document Server

    Bonthond, J; Ducimetière, L; Jansson, U; Vossenberg, Eugène B

    2002-01-01

    The LHC beam extraction kicker system, MKD, is composed of 15 fast kicker magnets per beam to extract the particles in one turn from the collider and to dispose them, after dilution, on an external absorber. Each magnet is powered by a separate pulse generator. The original single branch generator consisted of a discharge capacitor in series with a solid state closing switch left bracket 1 right bracket operating at 30 kV. In combination with a parallel freewheel diode stack this generator produced a current pulse of 2.7 mus rise time, 18.5 kA amplitude and about 1.8 ms fall time, of which only about 90 mus are needed to dump the beam. The freewheel diode circuit is equipped with a flat top current droop compensation network, consisting of a low voltage, low stray inductance, high current discharge capacitor. Extensive reliability studies have meanwhile suggested to further increase the operational safety of this crucial system by equipping each generator with two parallel branches. This paper presents the re...

  15. ADGEN: An automated adjoint code generator for large-scale sensitivity analysis

    International Nuclear Information System (INIS)

    Pin, F.G.; Oblow, E.M.; Horwedel, J.E.; Lucius, J.L.

    1987-01-01

    This paper describes a new automated system, named ADGEN, which makes use of the strengths of computer calculus to automate the costly and time-consuming calculation of derivatives in FORTRAN computer codes, and automatically generate adjoint solutions of computer codes

  16. Fast Generation of Near-Optimal Plans for Eco-Efficient Stowage of Large Container Vessels

    DEFF Research Database (Denmark)

    Pacino, Dario; Delgado, Alberto; Jensen, Rune Møller

    2011-01-01

    Eco-efficient stowage plans that are both competitive and sustainable have become a priority for the shipping industry. Stowage planning is NP-hard and is a challenging optimization problem in practice. We propose a new 2-phase approach that generates near-optimal stowage plans and fulfills indus...

  17. Combining Compact Representation and Incremental Generation in Large Games with Sequential Strategies

    DEFF Research Database (Denmark)

    Bosansky, Branislav; Xin Jiang, Albert; Tambe, Milind

    2015-01-01

    representation of sequential strategies and linear programming, or by incremental strategy generation of iterative double-oracle methods. In this paper, we present novel hybrid of these two approaches: compact-strategy double-oracle (CS-DO) algorithm that combines the advantages of the compact representation...

  18. Modeling and solving a large-scale generation expansion planning problem under uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Shan; Ryan, Sarah M. [Iowa State University, Department of Industrial and Manufacturing Systems Engineering, Ames (United States); Watson, Jean-Paul [Sandia National Laboratories, Discrete Math and Complex Systems Department, Albuquerque (United States); Woodruff, David L. [University of California Davis, Graduate School of Management, Davis (United States)

    2011-11-15

    We formulate a generation expansion planning problem to determine the type and quantity of power plants to be constructed over each year of an extended planning horizon, considering uncertainty regarding future demand and fuel prices. Our model is expressed as a two-stage stochastic mixed-integer program, which we use to compute solutions independently minimizing the expected cost and the Conditional Value-at-Risk; i.e., the risk of significantly larger-than-expected operational costs. We introduce stochastic process models to capture demand and fuel price uncertainty, which are in turn used to generate trees that accurately represent the uncertainty space. Using a realistic problem instance based on the Midwest US, we explore two fundamental, unexplored issues that arise when solving any stochastic generation expansion model. First, we introduce and discuss the use of an algorithm for computing confidence intervals on obtained solution costs, to account for the fact that a finite sample of scenarios was used to obtain a particular solution. Second, we analyze the nature of solutions obtained under different parameterizations of this method, to assess whether the recommended solutions themselves are invariant to changes in costs. The issues are critical for decision makers who seek truly robust recommendations for generation expansion planning. (orig.)

  19. Efficient Mid-Infrared Supercontinuum Generation in Tapered Large Mode Area Chalcogenide Photonic Crystal Fibers

    DEFF Research Database (Denmark)

    Petersen, Christian Rosenberg; Engelsholm, Rasmus Dybbro; Markos, Christos

    2017-01-01

    Mid-infrared supercontinuum spanning from 1.8-9  μm with an output power of 41.5 mW is demonstrated by pumping tapered large mode area chalcogenide photonic crystal fibers using a 4 μm optical parametric source.......Mid-infrared supercontinuum spanning from 1.8-9  μm with an output power of 41.5 mW is demonstrated by pumping tapered large mode area chalcogenide photonic crystal fibers using a 4 μm optical parametric source....

  20. Timetable-based simulation method for choice set generation in large-scale public transport networks

    DEFF Research Database (Denmark)

    Rasmussen, Thomas Kjær; Anderson, Marie Karen; Nielsen, Otto Anker

    2016-01-01

    The composition and size of the choice sets are a key for the correct estimation of and prediction by route choice models. While existing literature has posed a great deal of attention towards the generation of path choice sets for private transport problems, the same does not apply to public...... transport problems. This study proposes a timetable-based simulation method for generating path choice sets in a multimodal public transport network. Moreover, this study illustrates the feasibility of its implementation by applying the method to reproduce 5131 real-life trips in the Greater Copenhagen Area...... and to assess the choice set quality in a complex multimodal transport network. Results illustrate the applicability of the algorithm and the relevance of the utility specification chosen for the reproduction of real-life path choices. Moreover, results show that the level of stochasticity used in choice set...

  1. Large artificially generated turbulent boundary layers for the study of atmospheric flows

    International Nuclear Information System (INIS)

    Guimaraes, Joao Henrique D.; Santos Junior, Sergio J.F. dos; Freire, Atila P. Silva; Jian, Su

    1999-01-01

    The present work discusses in detail the experimental conditions for the establishment of thick artificially generated turbulent boundary layer which can be classified as having the near characteristics of an atmospheric boundary layer. The paper describes the experimental arrangement, including the features of the designed wind tunnel and of the instrumentation. the boundary layer is made to develop over a surface fitted with wedge generators which are used to yield a very thick boundary layer. The flow conditions were validated against the following features: growth, structure, equilibrium and turbulent transport momentum. Results are presented for the following main flow variables: mean velocity, local skin-friction coefficient, boundary layer momentum thickness and the Clauser factor. The velocity boundary layer characteristics were shown to be in good agreement with the expected trend in view of the classical expressions found in literature. (author)

  2. Large-scale runoff generation – parsimonious parameterisation using high-resolution topography

    OpenAIRE

    L. Gong; S. Halldin; C.-Y. Xu

    2010-01-01

    World water resources have primarily been analysed by global-scale hydrological models in the last decades. Runoff generation in many of these models are based on process formulations developed at catchments scales. The division between slow runoff (baseflow) and fast runoff is primarily governed by slope and spatial distribution of effective water storage capacity, both acting a very small scales. Many hydrological models, e.g. VIC, account for the spatial storage variability in terms...

  3. Generation of large scale urban environments to support advanced sensor and seeker simulation

    Science.gov (United States)

    Giuliani, Joseph; Hershey, Daniel; McKeown, David, Jr.; Willis, Carla; Van, Tan

    2009-05-01

    One of the key aspects for the design of a next generation weapon system is the need to operate in cluttered and complex urban environments. Simulation systems rely on accurate representation of these environments and require automated software tools to construct the underlying 3D geometry and associated spectral and material properties that are then formatted for various objective seeker simulation systems. Under an Air Force Small Business Innovative Research (SBIR) contract, we have developed an automated process to generate 3D urban environments with user defined properties. These environments can be composed from a wide variety of source materials, including vector source data, pre-existing 3D models, and digital elevation models, and rapidly organized into a geo-specific visual simulation database. This intermediate representation can be easily inspected in the visible spectrum for content and organization and interactively queried for accuracy. Once the database contains the required contents, it can then be exported into specific synthetic scene generation runtime formats, preserving the relationship between geometry and material properties. To date an exporter for the Irma simulation system developed and maintained by AFRL/Eglin has been created and a second exporter to Real Time Composite Hardbody and Missile Plume (CHAMP) simulation system for real-time use is currently being developed. This process supports significantly more complex target environments than previous approaches to database generation. In this paper we describe the capabilities for content creation for advanced seeker processing algorithms simulation and sensor stimulation, including the overall database compilation process and sample databases produced and exported for the Irma runtime system. We also discuss the addition of object dynamics and viewer dynamics within the visual simulation into the Irma runtime environment.

  4. Generation and saturation of large-scale flows in flute turbulence

    International Nuclear Information System (INIS)

    Sandberg, I.; Isliker, H.; Pavlenko, V. P.; Hizanidis, K.; Vlahos, L.

    2005-01-01

    The excitation and suppression of large-scale anisotropic modes during the temporal evolution of a magnetic-curvature-driven electrostatic flute instability are numerically investigated. The formation of streamerlike structures is attributed to the linear development of the instability while the subsequent excitation of the zonal modes is the result of the nonlinear coupling between linearly grown flute modes. When the amplitudes of the zonal modes become of the same order as that of the streamer modes, the flute instabilities get suppressed and poloidal (zonal) flows dominate. In the saturated state that follows, the dominant large-scale modes of the potential and the density are self-organized in different ways, depending on the value of the ion temperature

  5. Prospects for generating electricity by large onshore and offshore wind farms

    DEFF Research Database (Denmark)

    Volker, Patrick; Hahmann, Andrea N.; Badger, Jake

    2017-01-01

    large wind farms, winds can decrease considerably from their free-stream values to a point where an equilibrium wind speed is reached. The magnitude of this equilibrium wind speed is primarily dependent on the balance between turbine drag force and the downward momentum influx from above the wind farm......The decarbonisation of energy sources requires additional investments in renewable technologies, including the installation of onshore and offshore wind farms. For wind energy to remain competitive, wind farms must continue to provide low-cost power even when covering larger areas. Inside very...... on the local free-stream wind speed, the surface characteristics, and the turbine density. In onshore regions with moderate winds the power density of very large wind farms reaches 1 W m−2, whereas in offshore regions with very strong winds it exceeds 3 W m−2. Despite a relatively low power density, onshore...

  6. Maximal aerobic and anaerobic power generation in large crocodiles versus mammals: implications for dinosaur gigantothermy.

    Science.gov (United States)

    Seymour, Roger S

    2013-01-01

    Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic.

  7. Maximal aerobic and anaerobic power generation in large crocodiles versus mammals: implications for dinosaur gigantothermy.

    Directory of Open Access Journals (Sweden)

    Roger S Seymour

    Full Text Available Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic.

  8. Economical evaluation of large-scale photovoltaic systems using Universal Generating Function techniques

    DEFF Research Database (Denmark)

    Ding, Yi; Shen, Weixiang; Levitin, Gregory

    2013-01-01

    . The reliability models of solar panel arrays, PV inverters and energy production units (EPUs) are represented as the corresponding UGFs. The expected energy production models for different PV system configurations have also been developed. The expected unit cost of electricity has been calculated to provide......Solar energy plays an important role in the global energy framework for future. Comparing with conventional generation systems using fossil fuels, the cost structure of photovoltaic (PV) systems is different: the capital cost is higher while the operation cost is negligible. Reliabilities of the PV...

  9. ActivitySim: large-scale agent based activity generation for infrastructure simulation

    Energy Technology Data Exchange (ETDEWEB)

    Gali, Emmanuel [Los Alamos National Laboratory; Eidenbenz, Stephan [Los Alamos National Laboratory; Mniszewski, Sue [Los Alamos National Laboratory; Cuellar, Leticia [Los Alamos National Laboratory; Teuscher, Christof [PORTLAND STATE UNIV

    2008-01-01

    The United States' Department of Homeland Security aims to model, simulate, and analyze critical infrastructure and their interdependencies across multiple sectors such as electric power, telecommunications, water distribution, transportation, etc. We introduce ActivitySim, an activity simulator for a population of millions of individual agents each characterized by a set of demographic attributes that is based on US census data. ActivitySim generates daily schedules for each agent that consists of a sequence of activities, such as sleeping, shopping, working etc., each being scheduled at a geographic location, such as businesses or private residences that is appropriate for the activity type and for the personal situation of the agent. ActivitySim has been developed as part of a larger effort to understand the interdependencies among national infrastructure networks and their demand profiles that emerge from the different activities of individuals in baseline scenarios as well as emergency scenarios, such as hurricane evacuations. We present the scalable software engineering principles underlying ActivitySim, the socia-technical modeling paradigms that drive the activity generation, and proof-of-principle results for a scenario in the Twin Cities, MN area of 2.6 M agents.

  10. Recreating Raven's: software for systematically generating large numbers of Raven-like matrix problems with normed properties.

    Science.gov (United States)

    Matzen, Laura E; Benz, Zachary O; Dixon, Kevin R; Posey, Jamie; Kroger, James K; Speed, Ann E

    2010-05-01

    Raven's Progressive Matrices is a widely used test for assessing intelligence and reasoning ability (Raven, Court, & Raven, 1998). Since the test is nonverbal, it can be applied to many different populations and has been used all over the world (Court & Raven, 1995). However, relatively few matrices are in the sets developed by Raven, which limits their use in experiments requiring large numbers of stimuli. For the present study, we analyzed the types of relations that appear in Raven's original Standard Progressive Matrices (SPMs) and created a software tool that can combine the same types of relations according to parameters chosen by the experimenter, to produce very large numbers of matrix problems with specific properties. We then conducted a norming study in which the matrices we generated were compared with the actual SPMs. This study showed that the generated matrices both covered and expanded on the range of problem difficulties provided by the SPMs.

  11. Wind power integration into the automatic generation control of power systems with large-scale wind power

    DEFF Research Database (Denmark)

    Basit, Abdul; Hansen, Anca Daniela; Altin, Müfit

    2014-01-01

    Transmission system operators have an increased interest in the active participation of wind power plants (WPP) in the power balance control of power systems with large wind power penetration. The emphasis in this study is on the integration of WPPs into the automatic generation control (AGC......) of the power system. The present paper proposes a coordinated control strategy for the AGC between combined heat and power plants (CHPs) and WPPs to enhance the security and the reliability of a power system operation in the case of a large wind power penetration. The proposed strategy, described...... and exemplified for the future Danish power system, takes the hour-ahead regulating power plan for generation and power exchange with neighbouring power systems into account. The performance of the proposed strategy for coordinated secondary control is assessed and discussed by means of simulations for different...

  12. A microfluidic platform for generating large-scale nearly identical human microphysiological system arrays

    Science.gov (United States)

    Hsu, Yu-Hsiang; Moya, Monica L.; Hughes, Christopher C.W.; Georgea, Steven C.; Lee, Abraham P.

    2013-01-01

    This paper reports a polydimethylsiloxane microfluidic model system that can develop an array of nearly identical human microtissues with interconnected vascular networks. The microfluidic system design is based on an analogy with an electric circuit, applying resistive circuit concepts to design pressure dividers in serially-connected microtissue chambers. A long microchannel (550, 620 and 775 mm) creates a resistive circuit with a large hydraulic resistance. Two media reservoirs with a large cross-sectional area and of different heights are connected to the entrance and exit of the long microchannel to serve as a pressure source, and create a near constant pressure drop along the long microchannel. Microtissue chambers (0.12 μl) serve as a two-terminal resistive component with an input impedance > 50-fold larger than the long microchannel. Connecting each microtissue chamber to two different positions along the long microchannel creates a series of pressure dividers. Each microtissue chamber enables a controlled pressure drop of a segment of the microchannel without altering the hydrodynamic behaviour of the microchannel. The result is a controlled and predictable microphysiological environment within the microchamber. Interstitial flow, a mechanical cue for stimulating vasculogenesis, was verified by finite element simulation and experiments. The simplicity of this design enabled the development of multiple microtissue arrays (5, 12, and 30 microtissues) by co-culturing endothelial cells, stromal cells, and fibrin within the microchambers over two and three week periods. This methodology enables the culturing of a large array of microtissues with interconnected vascular networks for biological studies and applications such as drug development. PMID:23723013

  13. Generation of large-scale maps of science and associated indicators.

    Energy Technology Data Exchange (ETDEWEB)

    Klavans, Richard (SciTech Strategies, Inc., Berwyn, PA); Boyack, Kevin W.

    2005-12-01

    Over the past several years, techniques have been developed for clustering very large segments of the technical literature using sources such as Thomson ISI's Science Citation Index. The primary objective of this work has been to develop indicators of potential impact at the paper level to enhance planning and evaluation of research. These indicators can also be aggregated at different levels to enable profiling of departments, institutions, agencies, etc. Results of this work are presented as maps of science and technology with various overlays corresponding to the indicators associated with a particular search or question.

  14. Generation and analysis of expressed sequence tags in the extreme large genomes Lilium and Tulipa

    Directory of Open Access Journals (Sweden)

    Shahin Arwa

    2012-11-01

    Full Text Available Abstract Background Bulbous flowers such as lily and tulip (Liliaceae family are monocot perennial herbs that are economically very important ornamental plants worldwide. However, there are hardly any genetic studies performed and genomic resources are lacking. To build genomic resources and develop tools to speed up the breeding in both crops, next generation sequencing was implemented. We sequenced and assembled transcriptomes of four lily and five tulip genotypes using 454 pyro-sequencing technology. Results Successfully, we developed the first set of 81,791 contigs with an average length of 514 bp for tulip, and enriched the very limited number of 3,329 available ESTs (Expressed Sequence Tags for lily with 52,172 contigs with an average length of 555 bp. The contigs together with singletons covered on average 37% of lily and 39% of tulip estimated transcriptome. Mining lily and tulip sequence data for SSRs (Simple Sequence Repeats showed that di-nucleotide repeats were twice more abundant in UTRs (UnTranslated Regions compared to coding regions, while tri-nucleotide repeats were equally spread over coding and UTR regions. Two sets of single nucleotide polymorphism (SNP markers suitable for high throughput genotyping were developed. In the first set, no SNPs flanking the target SNP (50 bp on either side were allowed. In the second set, one SNP in the flanking regions was allowed, which resulted in a 2 to 3 fold increase in SNP marker numbers compared with the first set. Orthologous groups between the two flower bulbs: lily and tulip (12,017 groups and among the three monocot species: lily, tulip, and rice (6,900 groups were determined using OrthoMCL. Orthologous groups were screened for common SNP markers and EST-SSRs to study synteny between lily and tulip, which resulted in 113 common SNP markers and 292 common EST-SSR. Lily and tulip contigs generated were annotated and described according to Gene Ontology terminology. Conclusions

  15. Generation and analysis of expressed sequence tags in the extreme large genomes Lilium and Tulipa.

    Science.gov (United States)

    Shahin, Arwa; van Kaauwen, Martijn; Esselink, Danny; Bargsten, Joachim W; van Tuyl, Jaap M; Visser, Richard G F; Arens, Paul

    2012-11-20

    Bulbous flowers such as lily and tulip (Liliaceae family) are monocot perennial herbs that are economically very important ornamental plants worldwide. However, there are hardly any genetic studies performed and genomic resources are lacking. To build genomic resources and develop tools to speed up the breeding in both crops, next generation sequencing was implemented. We sequenced and assembled transcriptomes of four lily and five tulip genotypes using 454 pyro-sequencing technology. Successfully, we developed the first set of 81,791 contigs with an average length of 514 bp for tulip, and enriched the very limited number of 3,329 available ESTs (Expressed Sequence Tags) for lily with 52,172 contigs with an average length of 555 bp. The contigs together with singletons covered on average 37% of lily and 39% of tulip estimated transcriptome. Mining lily and tulip sequence data for SSRs (Simple Sequence Repeats) showed that di-nucleotide repeats were twice more abundant in UTRs (UnTranslated Regions) compared to coding regions, while tri-nucleotide repeats were equally spread over coding and UTR regions. Two sets of single nucleotide polymorphism (SNP) markers suitable for high throughput genotyping were developed. In the first set, no SNPs flanking the target SNP (50 bp on either side) were allowed. In the second set, one SNP in the flanking regions was allowed, which resulted in a 2 to 3 fold increase in SNP marker numbers compared with the first set. Orthologous groups between the two flower bulbs: lily and tulip (12,017 groups) and among the three monocot species: lily, tulip, and rice (6,900 groups) were determined using OrthoMCL. Orthologous groups were screened for common SNP markers and EST-SSRs to study synteny between lily and tulip, which resulted in 113 common SNP markers and 292 common EST-SSR. Lily and tulip contigs generated were annotated and described according to Gene Ontology terminology. Two transcriptome sets were built that are valuable

  16. Influence of ventilation structure on air flow distribution of large turbo-generator

    Science.gov (United States)

    Zhang, Liying; Ding, Shuye; Zhao, Zhijun; Yang, Jingmo

    2018-04-01

    For the 350 MW air - cooled turbo—generator, the rotor body is ventilated by sub -slots and 94 radial ventilation ducts and the end adopts arc segment and the straight section to acquire the wind. The stator is ventilated with five inlets and eight outlet air branches. In order to analyze the cooling effect of different ventilation schemes, a global physical model including the stator, rotor, casing and fan is established, and the assumptions and boundary conditions of the solution domain are given. the finite volume method is used to solve the problem, and the air flow distribution characteristics of each part of the motor under different ventilation schemes are obtained. The results show that the baffle at the end of the rotor can eliminate the eddy current at the end of the rotor, and make the flow distribution of cooling air more uniform and reasonable. The conclusions can provide reference for the design of motor ventilation structure.

  17. Control and Protection in Low Voltage Grid with Large Scale Renewable Electricity Generation

    DEFF Research Database (Denmark)

    Mustafa, Ghullam

    of the inverter controllers must be developed to Voltage-Frequency (VF) mode; and the others in either PV or PQ modes. The operation of the MG with several PV inverters and single VF inverter is similar to the operation of MG with a synchronous machine as slack bus. The VF inverter establishes the voltage...... of renewable energy based DGs are reduced CO2 emission, reduced operational cost as almost no fuel is used for their operation and less transmission and distribution losses as these units are normally built near to the load centers. This has also resulted in some operational challenges due to the unpredictable...... nature of such power generation sources. Some of the operational challenges include voltage variations due to power fluctuations coming from the DG units. On the other hand, it has also opened up some opportunities. One of the opportunities is islanding operation of the distribution system with DG unit...

  18. Impact of a Cosmic Body into Earth's Ocean and the Generation of Large Tsunami Waves: Insight from Numerical Modeling

    Science.gov (United States)

    Wünnemann, K.; Collins, G. S.; Weiss, R.

    2010-12-01

    The strike of a cosmic body into a marine environment differs in several respects from impact on land. Oceans cover approximately 70% of the Earth's surface, implying not only that oceanic impact is a very likely scenario for future impacts but also that most impacts in Earth's history must have happened in marine environments. Therefore, the study of oceanic impact is imperative in two respects: (1) to quantify the hazard posed by future oceanic impacts, including the potential threat of large impact-generated tsunami-like waves, and (2) to reconstruct Earth's impact record by accounting for the large number of potentially undiscovered crater structures in the ocean crust. Reconstruction of the impact record is of crucial importance both for assessing the frequency of collision events in the past and for better predicting the probability of future impact. We summarize the advances in the study of oceanic impact over the last decades and focus in particular on how numerical models have improved our understanding of cratering in the oceanic environment and the generation of waves by impact. We focus on insight gleaned from numerical modeling studies into the deceleration of the projectile by the water, cratering of the ocean floor, the late stage modification of the crater due to gravitational collapse, and water resurge. Furthermore, we discuss the generation and propagation of large tsunami-like waves as a result of a strike of a cosmic body in marine environments.

  19. Generation and characterization of a perfect vortex beam with a large topological charge through a digital micromirror device.

    Science.gov (United States)

    Chen, Yue; Fang, Zhao-Xiang; Ren, Yu-Xuan; Gong, Lei; Lu, Rong-De

    2015-09-20

    Optical vortices are associated with a spatial phase singularity. Such a beam with a vortex is valuable in optical microscopy, hyper-entanglement, and optical levitation. In these applications, vortex beams with a perfect circle shape and a large topological charge are highly desirable. But the generation of perfect vortices with high topological charges is challenging. We present a novel method to create perfect vortex beams with large topological charges using a digital micromirror device (DMD) through binary amplitude modulation and a narrow Gaussian approximation. The DMD with binary holograms encoding both the spatial amplitude and the phase could generate fast switchable, reconfigurable optical vortex beams with significantly high quality and fidelity. With either the binary Lee hologram or the superpixel binary encoding technique, we were able to generate the corresponding hologram with high fidelity and create a perfect vortex with topological charge as large as 90. The physical properties of the perfect vortex beam produced were characterized through measurements of propagation dynamics and the focusing fields. The measurements show good consistency with the theoretical simulation. The perfect vortex beam produced satisfies high-demand utilization in optical manipulation and control, momentum transfer, quantum computing, and biophotonics.

  20. Can Effective Field Theory of inflation generate large tensor-to-scalar ratio within Randall–Sundrum single braneworld?

    International Nuclear Information System (INIS)

    Choudhury, Sayantan

    2015-01-01

    In this paper my prime objective is to explain the generation of large tensor-to-scalar ratio from the single field sub-Planckian inflationary paradigm within Randall–Sundrum (RS) single braneworld scenario in a model independent fashion. By explicit computation I have shown that the effective field theory prescription of brane inflation within RS single brane setup is consistent with sub-Planckian excursion of the inflaton field, which will further generate large value of tensor-to-scalar ratio, provided the energy density for inflaton degrees of freedom is high enough compared to the brane tension in high energy regime. Finally, I have mentioned the stringent theoretical constraint on positive brane tension, cut-off of the quantum gravity scale and bulk cosmological constant to get sub-Planckian field excursion along with large tensor-to-scalar ratio as recently observed by BICEP2 or at least generates the tensor-to-scalar ratio consistent with the upper bound of Planck (2013 and 2015) data and Planck+BICEP2+Keck Array joint constraint

  1. Tsunamis generated by long and thin granular landslides in a large flume

    Science.gov (United States)

    Miller, Garrett S.; Andy Take, W.; Mulligan, Ryan P.; McDougall, Scott

    2017-01-01

    In this experimental study, granular material is released down slope to investigate landslide-generated waves. Starting with a known volume and initial position of the landslide source, detailed data are obtained on the velocity and thickness of the granular flow, the shape and location of the submarine landslide deposit, the amplitude and shape of the near-field wave, the far-field wave evolution, and the wave runup elevation on a smooth impermeable slope. The experiments are performed on a 6.7 m long 30° slope on which gravity accelerates the landslides into a 2.1 m wide and 33.0 m long wave flume that terminates with a 27° runup ramp. For a fixed landslide volume of 0.34 m3, tests are conducted in a range of still water depths from 0.05 to 0.50 m. Observations from high-speed cameras and measurements from wave probes indicate that the granular landslide moves as a long and thin train of material, and that only a portion of the landslide (termed the "effective mass") is engaged in activating the leading wave. The wave behavior is highly dependent on the water depth relative to the size of the landslide. In deeper water, the near-field wave behaves as a stable solitary-like wave, while in shallower water, the wave behaves as a breaking dissipative bore. Overall, the physical model observations are in good agreement with the results of existing empirical equations when the effective mass is used to predict the maximum near-field wave amplitude, the far-field amplitude, and the runup of tsunamis generated by granular landslides.

  2. High-throughput film-densitometry: An efficient approach to generate large data sets

    Energy Technology Data Exchange (ETDEWEB)

    Typke, Dieter; Nordmeyer, Robert A.; Jones, Arthur; Lee, Juyoung; Avila-Sakar, Agustin; Downing, Kenneth H.; Glaeser, Robert M.

    2004-07-14

    A film-handling machine (robot) has been built which can, in conjunction with a commercially available film densitometer, exchange and digitize over 300 electron micrographs per day. Implementation of robotic film handling effectively eliminates the delay and tedium associated with digitizing images when data are initially recorded on photographic film. The modulation transfer function (MTF) of the commercially available densitometer is significantly worse than that of a high-end, scientific microdensitometer. Nevertheless, its signal-to-noise ratio (S/N) is quite excellent, allowing substantial restoration of the output to ''near-to-perfect'' performance. Due to the large area of the standard electron microscope film that can be digitized by the commercial densitometer (up to 10,000 x 13,680 pixels with an appropriately coded holder), automated film digitization offers a fast and inexpensive alternative to high-end CCD cameras as a means of acquiring large amounts of image data in electron microscopy.

  3. Transient heating and entropy generation of a fluid inside a large aspect ratio cavity

    International Nuclear Information System (INIS)

    Cajas, J.C.; Trevino, C.

    2013-01-01

    In this work, the transient heating of a fluid inside a vertical cavity of large aspect ratio (height/length) was studied numerically by the use of the SIMPLE algorithm. The heat sources are two vertical plates localized in the side walls of the cavity near the bottom. Calculations were performed for a fixed value of the Prandtl number, Pr = 7, aspect ratio of 12 and six different Rayleigh numbers between 10 3 and 10 6 . The temperature and entropy production fields, the non-dimensional heat flux on the heated plates (given by the average Nusselt number) have been obtained. From a clear dependence on the Rayleigh number, different mechanisms of symmetry break and heat transfer in the cavity were found, where vortices dynamics play a very important role. A universal behavior of the mean values of the overall reduced entropy production rate was found, valid after a short initial transient. (authors)

  4. Large-scale demonstration of reliability centered maintenance at two nuclear generating stations

    International Nuclear Information System (INIS)

    Gaertner, J.P.; Edgar, C.; Rodin, M.E.

    1989-01-01

    This paper reports that after successful single-system pilot applications of Reliability Centered Maintenance (RCM) at various utilities, EPRI with Rochester Gas and Electric and Southern California Edison is undertaking multiple-system applications of RCM at their respective nuclear plants. The objective is to demonstrate the feasibility and cost-effectiveness of large-scale RCM application. In addition, each utility has plant-specific objectives to improve maintenance and plant availability. Each project has selected a prioritized list of some 15-20 systems on which to perform RCM. Each project is employing somewhat different RCM analysis methods, both of which conform to a global RCM definition applicable to all EPRI RCM work to date. Each project has developed important insights for improving cost and value of future analyses. Both projects will have applied the RCM process, including implementation, on several plant systems by April 1989

  5. Model development to acceptability-assessment of large scale power plants for electricity generation

    International Nuclear Information System (INIS)

    Schubert, Katharina

    2013-01-01

    An approach to specific assessment of large power plants is presented. This approach is intended to provide the decision which kind of nuclear, fossil and renewable installation operation minimizes unacceptable consequences for the environment, economy, and society. The tool ACCEPPT, which is currently under development for this purpose, allows a comprehensible and quantitative assessment of the reasonableness of unintended side-effects of different power plant types. The flexible design of the tool elements frame conditions and system technology supports a dynamic acceptability assessment under consideration of the particular context and plant configuration. Thus, current conditions can be used for evaluation as well as development scenarios. Finally the comprehensible acceptability results are intended to contribute overcoming of acceptance problems in the society. (orig.)

  6. [Sequencing by hybridization methods to generate large arrays of oligonucleotides]. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The subject of this project is to address a pressing need for custom DNA microarrays (chips) which can be easily and at low cost formatted and revised for research. In this sense, the term custom means chips for which there is need for limited quantities (less than hundreds) of any particular chip design which contains a large number of different, users defined sequences. Of the three principal approaches to fabricate DNA microarrays, the two which have been commercialized (a and b below) are not particularly suited to research purposes because of the significant time and costs required, once a result is obtained, to utilize that result in the design of a new and better chip: (a) the photodeprotection scheme used by Affymetrix; and (b) the spotting of pre-synthesized oligos or c-DNA onto surfaces.

  7. Optimal Load Shedding and Generation Rescheduling for Overload Suppression in Large Power Systems.

    Science.gov (United States)

    Moon, Young-Hyun

    Ever-increasing size, complexity and operation costs in modern power systems have stimulated the intensive study of an optimal Load Shedding and Generator Rescheduling (LSGR) strategy in the sense of a secure and economic system operation. The conventional approach to LSGR has been based on the application of LP (Linear Programming) with the use of an approximately linearized model, and the LP algorithm is currently considered to be the most powerful tool for solving the LSGR problem. However, all of the LP algorithms presented in the literature essentially lead to the following disadvantages: (i) piecewise linearization involved in the LP algorithms requires the introduction of a number of new inequalities and slack variables, which creates significant burden to the computing facilities, and (ii) objective functions are not formulated in terms of the state variables of the adopted models, resulting in considerable numerical inefficiency in the process of computing the optimal solution. A new approach is presented, based on the development of a new linearized model and on the application of QP (Quadratic Programming). The changes in line flows as a result of changes to bus injection power are taken into account in the proposed model by the introduction of sensitivity coefficients, which avoids the mentioned second disadvantages. A precise method to calculate these sensitivity coefficients is given. A comprehensive review of the theory of optimization is included, in which results of the development of QP algorithms for LSGR as based on Wolfe's method and Kuhn -Tucker theory are evaluated in detail. The validity of the proposed model and QP algorithms has been verified and tested on practical power systems, showing the significant reduction of both computation time and memory requirements as well as the expected lower generation costs of the optimal solution as compared with those obtained from computing the optimal solution with LP. Finally, it is noted that an

  8. A fast approach to generate large-scale topographic maps based on new Chinese vehicle-borne Lidar system

    International Nuclear Information System (INIS)

    Youmei, Han; Bogang, Yang

    2014-01-01

    Large -scale topographic maps are important basic information for city and regional planning and management. Traditional large- scale mapping methods are mostly based on artificial mapping and photogrammetry. The traditional mapping method is inefficient and limited by the environments. While the photogrammetry methods(such as low-altitude aerial mapping) is an economical and effective way to map wide and regulate range of large scale topographic map but doesn't work well in the small area due to the high cost of manpower and resources. Recent years, the vehicle-borne LIDAR technology has a rapid development, and its application in surveying and mapping is becoming a new topic. The main objective of this investigation is to explore the potential of vehicle-borne LIDAR technology to be used to fast mapping large scale topographic maps based on new Chinese vehicle-borne LIDAR system. It studied how to use the new Chinese vehicle-borne LIDAR system measurement technology to map large scale topographic maps. After the field data capture, it can be mapped in the office based on the LIDAR data (point cloud) by software which programmed by ourselves. In addition, the detailed process and accuracy analysis were proposed by an actual case. The result show that this new technology provides a new fast method to generate large scale topographic maps, which is high efficient and accuracy compared to traditional methods

  9. Comparison of large central and small decentralized power generation in India

    Energy Technology Data Exchange (ETDEWEB)

    None

    1997-05-01

    This reports evaluates two options for providing reliable power to rural areas in India. The benefits and costs are compared for biomass based distributed generation (DG) systems versus a 1200-MW central grid coal-fired power plant. The biomass based DG systems are examined both as alternatives to grid extension and as supplements to central grid power. The benefits are divided into three categories: those associated with providing reliable power from any source, those associated specifically with biomass based DG technology, and benefits of a central grid coal plant. The report compares the estimated delivered costs of electricity from the DG systems to those of the central plant. The analysis includes estimates for a central grid coal plant and four potential DG system technologies: Stirling engines, direct-fired combustion turbines, fuel cells, and biomass integrated gasification combined cycles. The report also discusses issues affecting India`s rural electricity demand, including economic development, power reliability, and environmental concerns. The results of the costs of electricity comparison between the biomass DG systems and the coal-fired central grid station demonstrated that the DG technologies may be able to produce very competitively priced electricity by the start of the next century. The use of DG technology may provide a practical means of addressing many rural electricity issues that India will face in the future. Biomass DG technologies in particular offer unique advantages for the environment and for economic development that will make them especially attractive. 58 refs., 31 figs.

  10. A large enhancement of photoinduced second harmonic generation in CdI2--Cu layered nanocrystals.

    Science.gov (United States)

    Miah, M Idrish

    2009-02-12

    Photoinduced second harmonic generation (PISHG) in undoped as well as in various Cu-doped (0.05-1.2% Cu) CdI2 nanocrystals was measured at liquid nitrogen temperature (LNT). It was found that the PISHG increases with increasing Cu doping up to approximately 0.6% and then decreases almost to that for the undoped CdI2 for doping higher than approximately 1%. The values of the second-order susceptibility ranged from 0.50 to 0.67 pm V(-1) for the Cu-doped nanocrystals with a thickness of 0.5 nm. The Cu-doping dependence shown in a parabolic fashion suggests a crucial role of the Cu agglomerates in the observed effects. The PISHG in crystals with various nanosizes was also measured at LNT. The size dependence demonstrated the quantum-confined effect with a maximum PISHG for 0.5 nm and with a clear increase in the PISHG with decreasing thickness of the nanocrystal. The Raman scattering spectra at different pumping powers were taken for thin nanocrystals, and the phonon modes originating from interlayer phonons were observed in the spectra. The results were discussed within a model of photoinduced electron-phonon anharmonicity.

  11. A Study of Large sin2φBs with High Mass Fourth Generation t'

    International Nuclear Information System (INIS)

    Ma Chien Yi

    2009-01-01

    The Standard Model predicts the CP violation phase φ SM Bs -M 12 ≅ (V * ts V tb ) in B s (bar) B s mixing is very small, of O(λ 2 η) ∼ -0.02, any finite value of φ Bs measured at the Tevatron would mean New Physics. Recent hints for finite sin2φ Bs have appeared from CDF and D 0 experiments at the Tevatron Run II. We consider the possibility to account for it with the 4 th generation t' quark. Considering recent direct search bounds, we set the mass to be near the unitarity bound of 600 GeV. Combining the measurement values of Δm Bs with B(B d → X s l + l - , together with typical f Bs values, we find a sizable sin2φ SM4 B s ∼ -0.3. Using a typical value of m b' = 580 GeV, we get a narrow range of values, 0.089 t'b | + → π + ν(bar)ν) and Δm D 0. Finally, we use the ZFITTER code to check the global fit deviation. (author)

  12. Connecting small ligands to generate large tubular metal-organic architectures

    International Nuclear Information System (INIS)

    Goforth, Andrea M.; Su, Cheng-Yong; Hipp, Rachael; Macquart, Rene B.; Smith, Mark D.; Loye, Hans-Conrad zur

    2005-01-01

    The new metal-organic framework materials, ZnF(Am 2 TAZ).solvents and ZnF(TAZ).solvents (Am 2 TAZ=3,5-diamino-1,2,4-triazole, TAZ=1,2,4-triazole), have been synthesized solvothermally and structurally characterized by either Rietveld refinement from powder XRD data or by single crystal X-ray diffraction. The three-dimensional structures of the compounds display open-ended, tubular channels, which are constituted of covalently bonded hexanuclear metallamacrocycles (Zn 6 F 6 (ligand) 6 ). The tubular channels are subsequently covalently joined into a honeycomb-like hexagonal array to generate the three-dimensional porous framework. In the case of ZnF(Am 2 TAZ).solvents, hydrophilic -NH 2 groups point into the channels, effectively reducing their inner diameter relative to ZnF(TAZ).solvents. The present compounds are isostructural to one another and to the previously reported ZnF(AmTAZ).solvents (AmTAZ=3-amino-1,2,4-triazole), illustrative of the fact that the internal size and chemical properties of the framework may be altered by modification of the small, heterocyclic ligand. In addition to demonstrating the ability to modify the basic framework, ZnF(TAZ).solvents and ZnF(Am 2 TAZ).solvents are two of the most thermally stable coordination frameworks known to date. - Graphical abstract: Top view of the open-ended, honeycomb tubular architecture of ZnF(Am 2 TAZ)

  13. Challenges in the Setup of Large-scale Next-Generation Sequencing Analysis Workflows

    Directory of Open Access Journals (Sweden)

    Pranav Kulkarni

    Full Text Available While Next-Generation Sequencing (NGS can now be considered an established analysis technology for research applications across the life sciences, the analysis workflows still require substantial bioinformatics expertise. Typical challenges include the appropriate selection of analytical software tools, the speedup of the overall procedure using HPC parallelization and acceleration technology, the development of automation strategies, data storage solutions and finally the development of methods for full exploitation of the analysis results across multiple experimental conditions. Recently, NGS has begun to expand into clinical environments, where it facilitates diagnostics enabling personalized therapeutic approaches, but is also accompanied by new technological, legal and ethical challenges. There are probably as many overall concepts for the analysis of the data as there are academic research institutions. Among these concepts are, for instance, complex IT architectures developed in-house, ready-to-use technologies installed on-site as well as comprehensive Everything as a Service (XaaS solutions. In this mini-review, we summarize the key points to consider in the setup of the analysis architectures, mostly for scientific rather than diagnostic purposes, and provide an overview of the current state of the art and challenges of the field.

  14. Comparison of large central and small decentralized power generation in India

    International Nuclear Information System (INIS)

    1997-05-01

    This reports evaluates two options for providing reliable power to rural areas in India. The benefits and costs are compared for biomass based distributed generation (DG) systems versus a 1200-MW central grid coal-fired power plant. The biomass based DG systems are examined both as alternatives to grid extension and as supplements to central grid power. The benefits are divided into three categories: those associated with providing reliable power from any source, those associated specifically with biomass based DG technology, and benefits of a central grid coal plant. The report compares the estimated delivered costs of electricity from the DG systems to those of the central plant. The analysis includes estimates for a central grid coal plant and four potential DG system technologies: Stirling engines, direct-fired combustion turbines, fuel cells, and biomass integrated gasification combined cycles. The report also discusses issues affecting India's rural electricity demand, including economic development, power reliability, and environmental concerns. The results of the costs of electricity comparison between the biomass DG systems and the coal-fired central grid station demonstrated that the DG technologies may be able to produce very competitively priced electricity by the start of the next century. The use of DG technology may provide a practical means of addressing many rural electricity issues that India will face in the future. Biomass DG technologies in particular offer unique advantages for the environment and for economic development that will make them especially attractive. 58 refs., 31 figs

  15. Use of δN formalism-difficulties in generating large local-type non-Gaussianity during inflation

    International Nuclear Information System (INIS)

    Tanaka, Takahiro; Suyama, Teruaki; Yokoyama, Shuichiro

    2010-01-01

    We discuss the generation of non-Gaussianity in density perturbation through the super-horizon evolution during inflation by using the so-called δN formalism. We first provide a general formula for the nonlinearity parameter generated during inflation. We find that it is proportional to the slow-roll parameters, multiplied by the model-dependent factors that may enhance non-Gaussianity to the observable ranges. Then we discuss three typical examples to illustrate how difficult it is to generate sizable non-Gaussianity through the super-horizon evolution during inflation. The first example is the double inflation model, which shows that temporal violation of slow-roll conditions is not enough for the generation of non-Gaussianity. The second example is the ordinary hybrid inflation model, which illustrates the importance of taking into account perturbations on small scales. Finally, we discuss the Kadota-Stewart model. This model gives an example in which we have to choose rather unnatural initial conditions even if large non-Gaussianity can be generated.

  16. Large Hadron Collider at CERN: Beams Generating High-Energy-Density Matter

    CERN Document Server

    Tahir, N A; Shutov, A; Lomonosov, IV; Piriz, A R; Hoffmann, D H H; Deutsch, C; Fortov, V E

    2009-01-01

    This paper presents numerical simulations that have been carried out to study the thermodynamic and hydrodynamic response of a solid copper cylindrical target that is facially irradiated along the axis by one of the two Large Hadron Collider (LHC) 7 TeV/c proton beams. The energy deposition by protons in solid copper has been calculated using an established particle interaction and Monte Carlo code, FLUKA, which is capable of simulating all components of the particle cascades in matter, up to multi-TeV energies. This data has been used as input to a sophisticated two--dimensional hydrodynamic computer code, BIG2 that has been employed to study this problem. The prime purpose of these investigations was to assess the damage caused to the equipment if the entire LHC beam is lost at a single place. The FLUKA calculations show that the energy of protons will be deposited in solid copper within about 1~m assuming constant material parameters. Nevertheless, our hydrodynamic simulations have shown that the energy de...

  17. Large-Scale Selection and Breeding To Generate Industrial Yeasts with Superior Aroma Production

    Science.gov (United States)

    Steensels, Jan; Meersman, Esther; Snoek, Tim; Saels, Veerle

    2014-01-01

    The concentrations and relative ratios of various aroma compounds produced by fermenting yeast cells are essential for the sensory quality of many fermented foods, including beer, bread, wine, and sake. Since the production of these aroma-active compounds varies highly among different yeast strains, careful selection of variants with optimal aromatic profiles is of crucial importance for a high-quality end product. This study evaluates the production of different aroma-active compounds in 301 different Saccharomyces cerevisiae, Saccharomyces paradoxus, and Saccharomyces pastorianus yeast strains. Our results show that the production of key aroma compounds like isoamyl acetate and ethyl acetate varies by an order of magnitude between natural yeasts, with the concentrations of some compounds showing significant positive correlation, whereas others vary independently. Targeted hybridization of some of the best aroma-producing strains yielded 46 intraspecific hybrids, of which some show a distinct heterosis (hybrid vigor) effect and produce up to 45% more isoamyl acetate than the best parental strains while retaining their overall fermentation performance. Together, our results demonstrate the potential of large-scale outbreeding to obtain superior industrial yeasts that are directly applicable for commercial use. PMID:25192996

  18. The Characteristics and Generating Mechanism of Large Precipitates in Ti-Containing H13 Tool Steel

    Science.gov (United States)

    Xie, You; Cheng, Guoguang; Chen, Lie; Zhang, Yandong; Yan, Qingzhong

    2017-02-01

    The characteristics of large precipitates in H13 tool steel with 0.015wt% Ti were studied. The result shows that three types of phases larger than 1 μm exist in the as-cast ingot, that is, (Ti, V) (C, N) type phase, (V, Mo, Cr)C type phase and sulfide. (Ti, V) (C, N) type phase could be further classified as the homogeneous Ti-rich one and the Ti-V-rich one in which Ti/V ratio gradually changes. (V, Mo, Cr)C type phase contains the V-rich one and the Mo-Cr-rich one. The compositional characteristics in all of them have little relation with the cutting position or cooling rate. The precipitating process could be well described through calculation by Thermo-Calc software. During solidification, the primary phase (Ti, V)(C, N) first starts to precipitate in the form of Ti-rich carbonitride. With the development of solidification, the ratio of Ti decreases and that of V increases. Then the primary phase Ti-V-rich (Ti, V)(C, N) and V-rich (V, Mo, Cr)C appears successively. Mo-Cr-rich (V, Mo, Cr)C phase does not precipitate until the solidification process reaches to the end. Sulfide precipitates before (V, Mo, Cr)C type phase and it could act as the nucleus of (V, Mo, Cr)C.

  19. Key Science Goals for a Next-generation Very Large Array

    Science.gov (United States)

    Murphy, Eric Joseph; ngVLA Science Advisory Council and all ngVLA Science Working Groups

    2018-01-01

    Inspired by dramatic discoveries from the Jansky VLA and ALMA, a plan to pursue a large collecting area radio interferometer that will open new discovery space from proto-planetary disks to distant galaxies is being developed by NRAO and the science community. Building on the superb cm observing conditions and existing infrastructure of the VLA site, the current vision of the ngVLA will be an interferometric array with more than 10 times the effective collecting area and spatial resolution of the current VLA and ALMA, that will operating at frequencies spanning ~1.2. – 116 GHz. The ngVLA will be optimized for observations at wavelengths between the exquisite performance of ALMA at submm wavelengths, and the future SKA-1 at decimeter to meter wavelengths, thus lending itself to be highly complementary with these facilities. As such, the ngVLA will open a new window on the universe through ultra-sensitive imaging of thermal line and continuum emission down to milliarcecond resolution, as well as deliver unprecedented broad band continuum polarimetric imaging of non-thermal processes. The ngVLA will be the only facility in the world that can tackle a broad range of outstanding scientific questions in modern astronomy by simultaneously delivering the capability to: unveil the formation of Solar System analogues; probe the initial conditions for planetary systems and life with astrochemistry; characterize the assembly, structure, and evolution of galaxies from the first billion years to the present; use pulsars in the Galactic center as fundamental tests of gravity; and understand the formation and evolution of stellar and supermassive blackholes in the era of multi-messenger astronomy.

  20. Symmetric aluminum-wire arrays generate high-quality Z pinches at large array radii

    International Nuclear Information System (INIS)

    Sanford, T.W.; Mock, R.C.; Spielman, R.B.; Peterson, D.L.; Mosher, D.; Roderick, N.F.

    1998-01-01

    A Saturn-accelerator study of annular, aluminum-wire array, Z-pinch implosions, in the calculated high-wire-number plasma-shell regime [Phys. Rev. Lett. 77, 5063 (1996)], shows that the radiated x-ray pulse width increases from about 4 nsec to about 7 nsec, when the radius of the array is increased from 8.75 to 20 mm at a fixed array mass of 0.6 mg. Eulerian radiation- magnetohydrodynamic code (E-RMHC) simulations in the r-z plane suggest that this pulse-width increase with radius is due to the faster growth of the shell thickness (that arises from a two-stage development in the magnetic Rayleigh - Taylor instability) relative to the increase in the shell implosion velocity. Over the array radii explored, the measured peak total x-ray power of ∼40 TW and energy of ∼325 kJ show little change outside of a ±15% shot-to-shot fluctuation and are consistent with the E-RMHC simulations. Similarly, the measured peak K-shell (lines plus continuum) power of ∼8 TW and energy of ∼70 kJ show little change with radius. The minimal change in K-shell yield is in agreement with simple K-shell radiation scaling models that assume a fixed radial compression for all initial array radii. These results suggest that the improved uniformity provided by the large number of wires in the initial array reduces the disruptive effects of the Rayleigh - Taylor instability observed in small-wire-number imploding loads. copyright 1998 American Institute of Physics

  1. Symmetric aluminum-wire arrays generate high-quality Z pinches at large array radii

    Energy Technology Data Exchange (ETDEWEB)

    Sanford, T.W.; Mock, R.C.; Spielman, R.B. [Sandia National Laboratories, P.O. Box 5800, Albuquerque, New Mexico 87185 (United States); Peterson, D.L. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545-0010 (United States); Mosher, D. [Naval Research Laboratory, Pulsed Power Physics Branch, Washington, DC 20375 (United States); Roderick, N.F. [University of New Mexico, Albuquerque, New Mexico 87131 (United States)

    1998-10-01

    A Saturn-accelerator study of annular, aluminum-wire array, Z-pinch implosions, in the calculated high-wire-number plasma-shell regime [Phys. Rev. Lett. {bold 77}, 5063 (1996)], shows that the radiated x-ray pulse width increases from about 4 nsec to about 7 nsec, when the radius of the array is increased from 8.75 to 20 mm at a fixed array mass of 0.6 mg. Eulerian radiation- magnetohydrodynamic code (E-RMHC) simulations in the r-z plane suggest that this pulse-width increase with radius is due to the faster growth of the shell thickness (that arises from a two-stage development in the magnetic Rayleigh{endash}Taylor instability) relative to the increase in the shell implosion velocity. Over the array radii explored, the measured peak total x-ray power of {approximately}40 TW and energy of {approximately}325 kJ show little change outside of a {plus_minus}15{percent} shot-to-shot fluctuation and are consistent with the E-RMHC simulations. Similarly, the measured peak {ital K}-shell (lines plus continuum) power of {approximately}8 TW and energy of {approximately}70 kJ show little change with radius. The minimal change in {ital K}-shell yield is in agreement with simple {ital K}-shell radiation scaling models that assume a fixed radial compression for all initial array radii. These results suggest that the improved uniformity provided by the large number of wires in the initial array reduces the disruptive effects of the Rayleigh{endash}Taylor instability observed in small-wire-number imploding loads. {copyright} {ital 1998 American Institute of Physics.}

  2. Symmetric aluminum-wire arrays generate high-quality Z pinches at large array radii

    Science.gov (United States)

    Sanford, T. W. L.; Mock, R. C.; Spielman, R. B.; Peterson, D. L.; Mosher, D.; Roderick, N. F.

    1998-10-01

    A Saturn-accelerator study of annular, aluminum-wire array, Z-pinch implosions, in the calculated high-wire-number plasma-shell regime [Phys. Rev. Lett. 77, 5063 (1996)], shows that the radiated x-ray pulse width increases from about 4 nsec to about 7 nsec, when the radius of the array is increased from 8.75 to 20 mm at a fixed array mass of 0.6 mg. Eulerian radiation- magnetohydrodynamic code (E-RMHC) simulations in the r-z plane suggest that this pulse-width increase with radius is due to the faster growth of the shell thickness (that arises from a two-stage development in the magnetic Rayleigh-Taylor instability) relative to the increase in the shell implosion velocity. Over the array radii explored, the measured peak total x-ray power of ˜40 TW and energy of ˜325 kJ show little change outside of a ±15% shot-to-shot fluctuation and are consistent with the E-RMHC simulations. Similarly, the measured peak K-shell (lines plus continuum) power of ˜8 TW and energy of ˜70 kJ show little change with radius. The minimal change in K-shell yield is in agreement with simple K-shell radiation scaling models that assume a fixed radial compression for all initial array radii. These results suggest that the improved uniformity provided by the large number of wires in the initial array reduces the disruptive effects of the Rayleigh-Taylor instability observed in small-wire-number imploding loads.

  3. Multiple stellar generations in the Large Magellanic Cloud Star Cluster NGC 1846

    Science.gov (United States)

    Milone, Antonino

    2010-09-01

    The recent discovery of multiple stellar populations in massive Galactic globular clusters poses a serious challenge for models of star cluster formation and evolution. The finding of multiple main sequences in the massive clusters NGC 2808 and omega Centauri, and multiple sub-giant-branch in NGC 1851 and many other globulars have demonstrated that star clusters are not as simple as we have imagined for decades. Surprisingly the only way to explain the main sequence splitting appears to be Helium enrichment, up to an astonishingly high Y 0.40.An unique angle on this problem can be provided by intermediate-age clusters in the Magellanic Clouds with peculiar main-sequence turn-off morphologies. Recent discoveries, based on ACS data of unparalleled photometric accuracy, have demonstrated that the CMDs of a large fraction of these clusters { 70 %} are not consistent with the simple, single stellar population hypothesis. Explanations for what conditions could give rise to multiple populations in Galactic Globular Clusters remain controversial; this is even more the case for LMC clustersTo properly constraint the multipopulation phenomenon in Magellanic Cloud star clusters, we propose deep UV/IR imaging of NGC 1846, a star cluster where multiple populations have already been identified. The proposed observation will allow us to accurately measure the age difference between the stellar populations providing fundamental clues on the formation mechanism. Our simulations of WFC3 performance suggest that we will be able to detect even the main sequence splitting caused by small He differences {Delta Y 0.02}.

  4. Large-scale road safety programmes in low- and middle-income countries: an opportunity to generate evidence.

    Science.gov (United States)

    Hyder, Adnan A; Allen, Katharine A; Peters, David H; Chandran, Aruna; Bishai, David

    2013-01-01

    The growing burden of road traffic injuries, which kill over 1.2 million people yearly, falls mostly on low- and middle-income countries (LMICs). Despite this, evidence generation on the effectiveness of road safety interventions in LMIC settings remains scarce. This paper explores a scientific approach for evaluating road safety programmes in LMICs and introduces such a road safety multi-country initiative, the Road Safety in 10 Countries Project (RS-10). By building on existing evaluation frameworks, we develop a scientific approach for evaluating large-scale road safety programmes in LMIC settings. This also draws on '13 lessons' of large-scale programme evaluation: defining the evaluation scope; selecting study sites; maintaining objectivity; developing an impact model; utilising multiple data sources; using multiple analytic techniques; maximising external validity; ensuring an appropriate time frame; the importance of flexibility and a stepwise approach; continuous monitoring; providing feedback to implementers, policy-makers; promoting the uptake of evaluation results; and understanding evaluation costs. The use of relatively new approaches for evaluation of real-world programmes allows for the production of relevant knowledge. The RS-10 project affords an important opportunity to scientifically test these approaches for a real-world, large-scale road safety evaluation and generate new knowledge for the field of road safety.

  5. Diagnosis of Short-Circuit Fault in Large-Scale Permanent-Magnet Wind Power Generator Based on CMAC

    Directory of Open Access Journals (Sweden)

    Chin-Tsung Hsieh

    2013-01-01

    Full Text Available This study proposes a method based on the cerebellar model arithmetic controller (CMAC for fault diagnosis of large-scale permanent-magnet wind power generators and compares the results with Error Back Propagation (EBP. The diagnosis is based on the short-circuit faults in permanent-magnet wind power generators, magnetic field change, and temperature change. Since CMAC is characterized by inductive ability, associative ability, quick response, and similar input signals exciting similar memories, it has an excellent effect as an intelligent fault diagnosis implement. The experimental results suggest that faults can be diagnosed effectively after only training CMAC 10 times. In comparison to training 151 times for EBP, CMAC is better than EBP in terms of training speed.

  6. Combined electrochemical, heat generation, and thermal model for large prismatic lithium-ion batteries in real-time applications

    Science.gov (United States)

    Farag, Mohammed; Sweity, Haitham; Fleckenstein, Matthias; Habibi, Saeid

    2017-08-01

    Real-time prediction of the battery's core temperature and terminal voltage is very crucial for an accurate battery management system. In this paper, a combined electrochemical, heat generation, and thermal model is developed for large prismatic cells. The proposed model consists of three sub-models, an electrochemical model, heat generation model, and thermal model which are coupled together in an iterative fashion through physicochemical temperature dependent parameters. The proposed parameterization cycles identify the sub-models' parameters separately by exciting the battery under isothermal and non-isothermal operating conditions. The proposed combined model structure shows accurate terminal voltage and core temperature prediction at various operating conditions while maintaining a simple mathematical structure, making it ideal for real-time BMS applications. Finally, the model is validated against both isothermal and non-isothermal drive cycles, covering a broad range of C-rates, and temperature ranges [-25 °C to 45 °C].

  7. Literature Review on Reasons and Countermeasures on Large-scale Off-grid of Wind Turbine Generator System

    Directory of Open Access Journals (Sweden)

    Zhu Jun

    2015-01-01

    Full Text Available This paper reviews the present situation of the application of wind turbines generator system(WTGS at home and abroad, describes the strategic significance and the value of sustainable development of the wind power in the country, illustrates the problems, a variety of reasons and responses on large-scale off-grid of WTGS, compares the advantages and disadvantages of various methods, gives full consideration to the actual demand for WTGS works and characteristics and points out the further research.

  8. Design and manufacture of a large superconducting homopolar motor (and status of superconducting a.c. generator)

    International Nuclear Information System (INIS)

    Appleton, A.D.

    1983-01-01

    This paper describes the design and manufacture of a large superconducting motor which, in the present time of financial restraints, is continuing at least to the point of having a completed cryostat with its superconducting winding operating with a dedicated helium refrigeration plant. Comments are also made on the superconducting a.c. generator project, although a final decision on the rating of a prototype and the approval of the funding has not yet been made, the selected rating is expected to be between 200 MW and 600 MW

  9. Generating functional and large N limit of nonlocal 2D generalized Yang-Mills theories (nlgYM2's)

    International Nuclear Information System (INIS)

    Saaidi, K.; Sajadi, H.M.

    2001-01-01

    Using the path integral method, we calculate the partition function and the generating functional (of the field strengths) on nonlocal generalized 2D Yang-Mills theories (nlgYM 2 's), which are nonlocal in the auxiliary field. This has been considered before by Saaidi and Khorrami. Our calculations are done for general surfaces. We find a general expression for the free energy of W(φ) =φ 2k in nlgYM 2 theories at the strong coupling phase (SCP) regime (A > A c ) for large groups. In the specific φ 4 model, we show that the theory has a third order phase transition. (orig.)

  10. A third-generation density-functional-theory-based method for calculating canonical molecular orbitals of large molecules.

    Science.gov (United States)

    Hirano, Toshiyuki; Sato, Fumitoshi

    2014-07-28

    We used grid-free modified Cholesky decomposition (CD) to develop a density-functional-theory (DFT)-based method for calculating the canonical molecular orbitals (CMOs) of large molecules. Our method can be used to calculate standard CMOs, analytically compute exchange-correlation terms, and maximise the capacity of next-generation supercomputers. Cholesky vectors were first analytically downscaled using low-rank pivoted CD and CD with adaptive metric (CDAM). The obtained Cholesky vectors were distributed and stored on each computer node in a parallel computer, and the Coulomb, Fock exchange, and pure exchange-correlation terms were calculated by multiplying the Cholesky vectors without evaluating molecular integrals in self-consistent field iterations. Our method enables DFT and massively distributed memory parallel computers to be used in order to very efficiently calculate the CMOs of large molecules.

  11. Wind power integration into the automatic generation control of power systems with large-scale wind power

    Directory of Open Access Journals (Sweden)

    Abdul Basit

    2014-10-01

    Full Text Available Transmission system operators have an increased interest in the active participation of wind power plants (WPP in the power balance control of power systems with large wind power penetration. The emphasis in this study is on the integration of WPPs into the automatic generation control (AGC of the power system. The present paper proposes a coordinated control strategy for the AGC between combined heat and power plants (CHPs and WPPs to enhance the security and the reliability of a power system operation in the case of a large wind power penetration. The proposed strategy, described and exemplified for the future Danish power system, takes the hour-ahead regulating power plan for generation and power exchange with neighbouring power systems into account. The performance of the proposed strategy for coordinated secondary control is assessed and discussed by means of simulations for different possible future scenarios, when wind power production in the power system is high and conventional production from CHPs is at a minimum level. The investigation results of the proposed control strategy have shown that the WPPs can actively help the AGC, and reduce the real-time power imbalance in the power system, by down regulating their production when CHPs are unable to provide the required response.

  12. Variability of Snow Ablation: Consequences for Runoff Generation at the Process Scale and Lessons for Large Cold Regions Catchments

    Science.gov (United States)

    Pomeroy, J. W.; Carey, S. K.; Granger, R. J.; Hedstrom, N. R.; Janowicz, R.; Pietroniro, A.; Quinton, W. L.

    2002-12-01

    The supply of water to large northern catchments such as the Mackenzie and Yukon Rivers is dominated by snowmelt runoff from first order mountain catchments. In order to understand the timing, peak and duration of the snowmelt freshet at larger scale it is important to appreciate the spatial and temporal variability of snowmelt and runoff processes at the source. For this reason a comprehensive hydrology study of a Yukon River headwaters catchment, Wolf Creek Research Basin, near Whitehorse, has focussed on the spatial variability of snow ablation and snowmelt runoff generation and the consequences for the water balance in a mountain tundra zone. In northern mountain tundra, surface energetics vary with receipt of solar radiation, shrub vegetation cover and initial snow accumulation. Therefore the timing of snowmelt is controlled by aspect, in that south facing slopes become snow-free 4-5 weeks before the north facing. Runoff generation differs widely between the slopes; there is normally no spring runoff generated from the south facing slope as all meltwater evaporates or infiltrates. On the north facing slope, snowmelt provides substantial runoff to hillside macropores which rapidly route water to the stream channel. Macropore distribution is associated with organic terrain and discontinuous permafrost, which in turn result from the summer surface energetics. Therefore the influence of small-scale snow redistribution and energetics as controlled by topography must be accounted for when calculating contributing areas to larger scale catchments, and estimating the effectiveness of snowfall in generating streamflow. This concept is quite distinct from the drainage controlled contributing area that has been found useful in temperate-zone hydrology.

  13. Non-smooth optimization methods for large-scale problems: applications to mid-term power generation planning

    International Nuclear Information System (INIS)

    Emiel, G.

    2008-01-01

    This manuscript deals with large-scale non-smooth optimization that may typically arise when performing Lagrangian relaxation of difficult problems. This technique is commonly used to tackle mixed-integer linear programming - or large-scale convex problems. For example, a classical approach when dealing with power generation planning problems in a stochastic environment is to perform a Lagrangian relaxation of the coupling constraints of demand. In this approach, a master problem coordinates local subproblems, specific to each generation unit. The master problem deals with a separable non-smooth dual function which can be maximized with, for example, bundle algorithms. In chapter 2, we introduce basic tools of non-smooth analysis and some recent results regarding incremental or inexact instances of non-smooth algorithms. However, in some situations, the dual problem may still be very hard to solve. For instance, when the number of dualized constraints is very large (exponential in the dimension of the primal problem), explicit dualization may no longer be possible or the update of dual variables may fail. In order to reduce the dual dimension, different heuristics were proposed. They involve a separation procedure to dynamically select a restricted set of constraints to be dualized along the iterations. This relax-and-cut type approach has shown its numerical efficiency in many combinatorial problems. In chapter 3, we show Primal-dual convergence of such strategy when using an adapted sub-gradient method for the dual step and under minimal assumptions on the separation procedure. Another limit of Lagrangian relaxation may appear when the dual function is separable in highly numerous or complex sub-functions. In such situation, the computational burden of solving all local subproblems may be preponderant in the whole iterative process. A natural strategy would be here to take full advantage of the dual separable structure, performing a dual iteration after having

  14. Modeling magnetic field and TEC signatures of large-amplitude acoustic and gravity waves generated by natural hazard events

    Science.gov (United States)

    Zettergren, M. D.; Snively, J. B.; Inchin, P.; Komjathy, A.; Verkhoglyadova, O. P.

    2017-12-01

    Ocean and solid earth responses during earthquakes are a significant source of large amplitude acoustic and gravity waves (AGWs) that perturb the overlying ionosphere-thermosphere (IT) system. IT disturbances are routinely detected following large earthquakes (M > 7.0) via GPS total electron content (TEC) observations, which often show acoustic wave ( 3-4 min periods) and gravity wave ( 10-15 min) signatures with amplitudes of 0.05-2 TECU. In cases of very large earthquakes (M > 8.0) the persisting acoustic waves are estimated to have 100-200 m/s compressional velocities in the conducting ionospheric E and F-regions and should generate significant dynamo currents and magnetic field signatures. Indeed, some recent reports (e.g. Hao et al, 2013, JGR, 118, 6) show evidence for magnetic fluctuations, which appear to be related to AGWs, following recent large earthquakes. However, very little quantitative information is available on: (1) the detailed spatial and temporal dependence of these magnetic fluctuations, which are usually observed at a small number of irregularly arranged stations, and (2) the relation of these signatures to TEC perturbations in terms of relative amplitudes, frequency, and timing for different events. This work investigates space- and time-dependent behavior of both TEC and magnetic fluctuations following recent large earthquakes, with the aim to improve physical understanding of these perturbations via detailed, high-resolution, two- and three-dimensional modeling case studies with a coupled neutral atmospheric and ionospheric model, MAGIC-GEMINI (Zettergren and Snively, 2015, JGR, 120, 9). We focus on cases inspired by the large Chilean earthquakes from the past decade (viz., the M > 8.0 earthquakes from 2010 and 2015) to constrain the sources for the model, i.e. size, frequency, amplitude, and timing, based on available information from ocean buoy and seismometer data. TEC data are used to validate source amplitudes and to constrain

  15. Jaw-muscle fiber architecture in tufted capuchins favors generating relatively large muscle forces without compromising jaw gape

    Science.gov (United States)

    Taylor, Andrea B.; Vinyard, Christopher J.

    2009-01-01

    Cebus apella is renowned for its dietary flexibility and capacity to exploit hard and tough objects. Cebus apella differs from other capuchins in displaying a suite of craniodental features that have been functionally and adaptively linked to their feeding behavior, particularly the generation and dissipation of relatively large jaw forces. We compared fiber architecture of the masseter and temporalis muscles between the tufted capuchin (C. apella; n = 12 ) and two “untufted” capuchins (C. capuchinus, n = 3; C. albifrons, n = 5). These three species share broadly similar diets, but tufted capuchins occasionally exploit mechanically challenging tissues. We tested the hypothesis that C. apella exhibits architectural properties of their jaw muscles that facilitate relatively large forces, including relatively greater physiologic cross-sectional areas (PCSA), more pinnate fibers, and lower ratios of mass to tetanic tension (Mass/P0). Results show some evidence supporting these predictions, as C. apella has relatively greater superficial masseter, whole masseter, and temporalis PCSAs, significantly so only for the temporalis following Bonferroni adjustment. Capuchins did not differ in pinnation angle or Mass/P0. As an architectural trade-off between maximizing muscle force and muscle excursion/contraction velocity, we also tested the hypothesis that C. apella exhibits relatively shorter muscle fibers. Contrary to our prediction, there are no significant differences in relative fiber lengths between tufted and untufted capuchins. Therefore, we attribute the relatively greater PCSAs in C. apella primarily to their larger muscle masses. These findings suggest that relatively large jaw-muscle PCSAs can be added to the suite of masticatory features that have been functionally linked to the exploitation of a more resistant diet by C. apella. By enlarging jaw-muscle mass to increase PCSA, rather than reducing fiber lengths and increasing pinnation, tufted capuchins appear

  16. A study to solve the variability of wind generation through integration of large-scale hydraulic generation; Um estudo para resolver a variabilidade da geracao eolica atraves da integracao em larga escala com geracao hidraulica

    Energy Technology Data Exchange (ETDEWEB)

    Emmerik, Emanuel Leonardus van; Steinberger, Johann Michael; Aredes, Mauricio [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEE/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Eletrica

    2010-07-01

    The optimal deployment of wind generation with the hydro generation is being investigated as a viable option to assist in resolving the constraints coming ahead as a consequence of the tendency of recovery in the Brazilian Amazon basin for expansion of generating facilities. It is in the validity of this research that this work is focused. The value is shown of feasibility studies of using water power generation to offset the variability of wind generation when it is deployed on a large scale. Preliminary results are presented for the variability of wind generation at various cycles, the variability of the availability of hydropower. (author)

  17. Methods to isolate a large amount of generative cells, sperm cells and vegetative nuclei from tomato pollen for omics analysis

    Directory of Open Access Journals (Sweden)

    Yunlong eLu

    2015-06-01

    Full Text Available The development of sperm cells from microspores involves a set of finely regulated molecular and cellular events and the coordination of these events. The mechanisms underlying these events and their interconnections remain a major challenge. Systems analysis of genome-wide molecular networks and functional modules with high-throughput omics approaches is crucial for understanding the mechanisms; however, this study is hindered because of the difficulty in isolating a large amount of cells of different types, especially generative cells (GCs, from the pollen. Here, we optimized the conditions of tomato pollen germination and pollen tube growth to allow for long-term growth of pollen tubes in vitro with sperm cells (SCs generated in the tube. Using this culture system, we developed methods for isolating GCs, SCs and vegetative-cell nuclei (VN from just-germinated tomato pollen grains and growing pollen tubes and their purification by Percoll density gradient centrifugation. The purity and viability of isolated GCs and SCs were confirmed by microscopy examination and fluorescein diacetate staining, respectively, and the integrity of VN was confirmed by propidium iodide staining. We could obtain about 1.5 million GCs and 2.0 million SCs each from 180 mg initiated pollen grains, and 10 million VN from 270 mg initiated pollen grains germinated in vitro in each experiment. These methods provide the necessary preconditions for systematic biology studies of SC development and differentiation in higher plants.

  18. Methods to isolate a large amount of generative cells, sperm cells and vegetative nuclei from tomato pollen for "omics" analysis.

    Science.gov (United States)

    Lu, Yunlong; Wei, Liqin; Wang, Tai

    2015-01-01

    The development of sperm cells (SCs) from microspores involves a set of finely regulated molecular and cellular events and the coordination of these events. The mechanisms underlying these events and their interconnections remain a major challenge. Systems analysis of genome-wide molecular networks and functional modules with high-throughput "omics" approaches is crucial for understanding the mechanisms; however, this study is hindered because of the difficulty in isolating a large amount of cells of different types, especially generative cells (GCs), from the pollen. Here, we optimized the conditions of tomato pollen germination and pollen tube growth to allow for long-term growth of pollen tubes in vitro with SCs generated in the tube. Using this culture system, we developed methods for isolating GCs, SCs and vegetative cell nuclei (VN) from just-germinated tomato pollen grains and growing pollen tubes and their purification by Percoll density gradient centrifugation. The purity and viability of isolated GCs and SCs were confirmed by microscopy examination and fluorescein diacetate staining, respectively, and the integrity of VN was confirmed by propidium iodide staining. We could obtain about 1.5 million GCs and 2.0 million SCs each from 180 mg initiated pollen grains, and 10 million VN from 270 mg initiated pollen grains germinated in vitro in each experiment. These methods provide the necessary preconditions for systematic biology studies of SC development and differentiation in higher plants.

  19. the Preliminary Research Based on Seismic Signals Generated by Hutubi Transmitting Seismic Station with One Large-volume Airgun Array

    Science.gov (United States)

    Wang, Q.; Su, J.; Wei, Y.; Zhang, W.; Wang, H.; Wang, B.; Ji, Z.

    2017-12-01

    For studying the subsurface structure and its subtle changes, we built the Hutubi transmitting seismic station with one large-volume airgun array at one artificial water pool in the northern segment of Tianshan mountain, where earthquakes occurred frequently. The airgun array consists of six airguns with every airgun capacity of 2000in3, and the artificial water pool with the top diameter of 100m, bottom diameter of 20m and the depth of 18m.We started the regular excitation experiment with the large-volume airgun source every week since June, 2013. Using seismic signals geneated by the Hutubi airgun source, we made the preliminary research on the airgun source, waveform characteristics and the subsurface velocity changes in the northern Tiansh mountain. The results are as follows: The seismic signal exited by the airgun source is characteristic of low-frequency ,and the dominant frequency is in the range of 2 6Hz. The Hutubi transmitting seismic station can continuously generate long-distance detectable and highly repeatable signals, and the correlation coefficient of sigals is greater than 0.95; and the longest propagation distance arrives to 380km, in addition, the 5000-shot stacked sigal using the phase weighted stack technique can be identified in the station, which is about 1300km from the Hutubi transmitting seismic station. Hutubi large-volume airgun source is fitted to detect and monitor the regional-scale subsurface stress state. Applying correlation test method, we measured weak subsurface velocity changes in the northern Tianshan mountain, and found that the several stations, which are within 150km from the the Hutubi transmitting seismic station, appeared 0.1 0.2% relative velocity changes before the Hutubi MS6.2 earthquake on Dec.8, 2016.

  20. Hydrogen and methane generation from large hydraulic plant: Thermo-economic multi-level time-dependent optimization

    International Nuclear Information System (INIS)

    Rivarolo, M.; Magistri, L.; Massardo, A.F.

    2014-01-01

    Highlights: • We investigate H 2 and CH 4 production from very large hydraulic plant (14 GW). • We employ only “spilled energy”, not used by hydraulic plant, for H 2 production. • We consider the integration with energy taken from the grid at different prices. • We consider hydrogen conversion in chemical reactors to produce methane. • We find plants optimal size using a time-dependent thermo-economic approach. - Abstract: This paper investigates hydrogen and methane generation from large hydraulic plant, using an original multilevel thermo-economic optimization approach developed by the authors. Hydrogen is produced by water electrolysis employing time-dependent hydraulic energy related to the water which is not normally used by the plant, known as “spilled water electricity”. Both the demand for spilled energy and the electrical grid load vary widely by time of year, therefore a time-dependent hour-by-hour one complete year analysis has been carried out, in order to define the optimal plant size. This time period analysis is necessary to take into account spilled energy and electrical load profiles variability during the year. The hydrogen generation plant is based on 1 MWe water electrolysers fuelled with the “spilled water electricity”, when available; in the remaining periods, in order to assure a regular H 2 production, the energy is taken from the electrical grid, at higher cost. To perform the production plant size optimization, two hierarchical levels have been considered over a one year time period, in order to minimize capital and variable costs. After the optimization of the hydrogen production plant size, a further analysis is carried out, with a view to converting the produced H 2 into methane in a chemical reactor, starting from H 2 and CO 2 which is obtained with CCS plants and/or carried by ships. For this plant, the optimal electrolysers and chemical reactors system size is defined. For both of the two solutions, thermo

  1. Cattle mammary bioreactor generated by a novel procedure of transgenic cloning for large-scale production of functional human lactoferrin.

    Directory of Open Access Journals (Sweden)

    Penghua Yang

    Full Text Available Large-scale production of biopharmaceuticals by current bioreactor techniques is limited by low transgenic efficiency and low expression of foreign proteins. In general, a bacterial artificial chromosome (BAC harboring most regulatory elements is capable of overcoming the limitations, but transferring BAC into donor cells is difficult. We describe here the use of cattle mammary bioreactor to produce functional recombinant human lactoferrin (rhLF by a novel procedure of transgenic cloning, which employs microinjection to generate transgenic somatic cells as donor cells. Bovine fibroblast cells were co-microinjected for the first time with a 150-kb BAC carrying the human lactoferrin gene and a marker gene. The resulting transfection efficiency of up to 15.79 x 10(-2 percent was notably higher than that of electroporation and lipofection. Following somatic cell nuclear transfer, we obtained two transgenic cows that secreted rhLF at high levels, 2.5 g/l and 3.4 g/l, respectively. The rhLF had a similar pattern of glycosylation and proteolytic susceptibility as the natural human counterpart. Biochemical analysis revealed that the iron-binding and releasing properties of rhLF were identical to that of native hLF. Importantly, an antibacterial experiment further demonstrated that rhLF was functional. Our results indicate that co-microinjection with a BAC and a marker gene into donor cells for somatic cell cloning indeed improves transgenic efficiency. Moreover, the cattle mammary bioreactors generated with this novel procedure produce functional rhLF on an industrial scale.

  2. On generation of Alfvenic-like fluctuations by drift wave-zonal flow system in large plasma device experiments

    International Nuclear Information System (INIS)

    Horton, W.; Correa, C.; Chagelishvili, G. D.; Avsarkisov, V. S.; Lominadze, J. G.; Perez, J. C.; Kim, J.-H.; Carter, T. A.

    2009-01-01

    According to recent experiments, magnetically confined fusion plasmas with ''drift wave-zonal flow turbulence'' (DW-ZF) give rise to broadband electromagnetic waves. Sharapov et al. [Europhysics Conference Abstracts, 35th EPS Conference on Plasma Physics, Hersonissos, 2008, edited by P. Lalousis and S. Moustaizis (European Physical Society, Switzerland, 2008), Vol. 32D, p. 4.071] reported an abrupt change in the magnetic turbulence during L-H transitions in Joint European Torus [P. H. Rebut and B. E. Keen, Fusion Technol. 11, 13 (1987)] plasmas. A broad spectrum of Alfvenic-like (electromagnetic) fluctuations appears from ExB flow driven turbulence in experiments on the large plasma device (LAPD) [W. Gekelman et al., Rev. Sci. Instrum. 62, 2875 (1991)] facility at UCLA. Evidence of the existence of magnetic fluctuations in the shear flow region in the experiments is shown. We present one possible theoretical explanation of the generation of electromagnetic fluctuations in DW-ZF systems for an example of LAPD experiments. The method used is based on generalizing results on shear flow phenomena from the hydrodynamics community. In the 1990s, it was realized that fluctuation modes of spectrally stable nonuniform (sheared) flows are non-normal. That is, the linear operators of the flows modal analysis are non-normal and the corresponding eigenmodes are not orthogonal. The non-normality results in linear transient growth with bursts of the perturbations and the mode coupling, which causes the generation of electromagnetic waves from the drift wave-shear flow system. We consider shear flow that mimics tokamak zonal flow. We show that the transient growth substantially exceeds the growth of the classical dissipative trapped-particle instability of the system.

  3. Temporal sequencing of throughfall drop generation as revealed by use of a large-scale rainfall simulator

    Science.gov (United States)

    Nanko, K.; Levia, D. F., Jr.; Iida, S.; SUN, X.; Shinohara, Y.; Sakai, N.

    2017-12-01

    Scientists have been interested in throughfall drop size and its distribution because of its importance to soil erosion and the forest water balance. An indoor experiment was employed to deepen our understanding of throughfall drop generation processes to promote better management of forested ecosystems. The indoor experiment provides a unique opportunity to examine an array of constant rainfall intensities that are ideal conditions to pick up the effect of changing intensities and not found in the fields. Throughfall drop generation was examined for three species- Cryptomeria japonica D. Don (Japanese cedar), Chamaecyparis obtusa (Siebold & Zucc.) Endl. (Japanese cypress), and Zelkova serrata Thunb. (Japanese zelkova)- under both leafed and leafless conditions in the large-scale rainfall simulator in the National Research Institute for Earth Science and Disaster Resilience (Tsukuba, Japan) at varying rainfall intensities ranging from15 to 100 mm h-1. Drop size distributions of the applied rainfall and throughfall were measured simultaneously by 20 laser disdrometers. Utilizing the drop size dataset, throughfall was separated into three components: free throughfall, canopy drip, and splash throughfall. The temporal sequencing of the throughfall components were analyzed on a 1-min interval during each experimental run. The throughfall component percentage and drop size of canopy drip differed among tree species and rainfall intensities and by elapsed time from the beginning of the rainfall event. Preliminary analysis revealed that the time differences to produce branch drip as compared to leaf (or needle) drip was partly due to differential canopy wet-up processes and the disappearance of branch drips due to canopy saturation, leading to dissimilar throughfall drop size distributions beneath the various tree species examined. This research was supported by JSPS Invitation Fellowship for Research in Japan (Grant No.: S16088) and JSPS KAKENHI (Grant No.: JP15H05626).

  4. A State-of-the-Art Report on Technologies of Volume Reduction and Self-Disposal for Large Metal Wastes including the Steam Generator of Nuclear Power Plants

    International Nuclear Information System (INIS)

    Lee, Kune Woo; Choi, W. K.; Kim, G. Y.

    2009-06-01

    This report focuses on technologies of volume reduction and self-disposal for large metal wastes including the steam generator of nuclear power plants. This report consists of the cases of treatments and foreign and domestic technologies for steam generator replacement

  5. Supermassive Black Hole Binaries: Multi-Messenger Astrophysics and Long Baselines with the Next-Generation Very Large Array

    Science.gov (United States)

    Burke-Spolaor, Sarah; Lazio, Joseph; Nyland, Kristina; Blecha, Laura; Bogdanovic, Tamara; Comerford, Julie; Liu, Xin; Taylor, Gregory; Shen, Yue; Maccarone, T. J.; Chomiuk, Laura; Reines, Amy

    2018-01-01

    Dual ( physical processes that drive both the remnant's dynamics and the inspiral of the black hole pair. A systematic census of the dual supermassive black hole population will also directly constrain the strength and distribution of objects emitting gravitational waves that will be detected by pulsar timing arrays and future space-based laser interferometers. Although the population of dual supermassive black holes in galaxy merger products is central to these topics and others, few have yet been discovered.A suite of radio, visible-infrared, and X-ray telescopes have just begun to reveal the population of kiloparsec-separation dual active nuclei. This poster will present the unique capability of radio observations to explore the dual and binary population of supermassive black hole binaries, and will highlight the observational techniques and discoveries expected for the Next-Generation Very Large Array.Part of this research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. The NANOGrav project receives support from NSF Physics Frontier Center award number 1430284.

  6. Survey and Classification of Large Woody Debris (LWD in Streams Using Generated Low-Cost Geomatic Products

    Directory of Open Access Journals (Sweden)

    Damian Ortega-Terol

    2014-11-01

    Full Text Available Water authorities are required to have a survey of large woody debris (LWD in river channels and to manage this aspect of the stream habitat, making decisions on removing, positioning or leaving LWD in a natural state. The main objective of this study is to develop a new methodology that assists in decision making for sustainable management of river channels by using generated low-cost, geomatic products to detect LWD. The use of low-cost photogrammetry based on the use of economical, conventional, non-metric digital cameras mounted on low-cost aircrafts, together with the use of the latest computational vision techniques and open-source geomatic tools, provides useful geomatic products. The proposed methodology, compared with conventional photogrammetry or other traditional methods, led to a cost savings of up to 45%. This work presents several contributions for the area of free and open source software related to Geographic Information System (FOSSGIS applications to LWD management in streams, while developing a QGIS [1] plugin that characterizes the risk from the automatic calculation of geometrical parameters.

  7. Large-scale dynamical influence of a gravity wave generated over the Antarctic Peninsula – regional modelling and budget analysis

    Directory of Open Access Journals (Sweden)

    JOEL Arnault

    2013-03-01

    Full Text Available The case study of a mountain wave triggered by the Antarctic Peninsula on 6 October 2005, which has already been documented in the literature, is chosen here to quantify the associated gravity wave forcing on the large-scale flow, with a budget analysis of the horizontal wind components and horizontal kinetic energy. In particular, a numerical simulation using the Weather Research and Forecasting (WRF model is compared to a control simulation with flat orography to separate the contribution of the mountain wave from that of other synoptic processes of non-orographic origin. The so-called differential budgets of horizontal wind components and horizontal kinetic energy (after subtracting the results from the simulation without orography are then averaged horizontally and vertically in the inner domain of the simulation to quantify the mountain wave dynamical influence at this scale. This allows for a quantitative analysis of the simulated mountain wave's dynamical influence, including the orographically induced pressure drag, the counterbalancing wave-induced vertical transport of momentum from the flow aloft, the momentum and energy exchanges with the outer flow at the lateral and upper boundaries, the effect of turbulent mixing, the dynamics associated with geostrophic re-adjustment of the inner flow, the deceleration of the inner flow, the secondary generation of an inertia–gravity wave and the so-called baroclinic conversion of energy between potential energy and kinetic energy.

  8. Gene Mutation Profiles in Primary Diffuse Large B Cell Lymphoma of Central Nervous System: Next Generation Sequencing Analyses

    Science.gov (United States)

    Todorovic Balint, Milena; Jelicic, Jelena; Mihaljevic, Biljana; Kostic, Jelena; Stanic, Bojana; Balint, Bela; Pejanovic, Nadja; Lucic, Bojana; Tosic, Natasa; Marjanovic, Irena; Stojiljkovic, Maja; Karan-Djurasevic, Teodora; Perisic, Ognjen; Rakocevic, Goran; Popovic, Milos; Raicevic, Sava; Bila, Jelena; Antic, Darko; Andjelic, Bosko; Pavlovic, Sonja

    2016-01-01

    The existence of a potential primary central nervous system lymphoma-specific genomic signature that differs from the systemic form of diffuse large B cell lymphoma (DLBCL) has been suggested, but is still controversial. We investigated 19 patients with primary DLBCL of central nervous system (DLBCL CNS) using the TruSeq Amplicon Cancer Panel (TSACP) for 48 cancer-related genes. Next generation sequencing (NGS) analyses have revealed that over 80% of potentially protein-changing mutations were located in eight genes (CTNNB1, PIK3CA, PTEN, ATM, KRAS, PTPN11, TP53 and JAK3), pointing to the potential role of these genes in lymphomagenesis. TP53 was the only gene harboring mutations in all 19 patients. In addition, the presence of mutated TP53 and ATM genes correlated with a higher total number of mutations in other analyzed genes. Furthermore, the presence of mutated ATM correlated with poorer event-free survival (EFS) (p = 0.036). The presence of the mutated SMO gene correlated with earlier disease relapse (p = 0.023), inferior event-free survival (p = 0.011) and overall survival (OS) (p = 0.017), while mutations in the PTEN gene were associated with inferior OS (p = 0.048). Our findings suggest that the TP53 and ATM genes could be involved in the molecular pathophysiology of primary DLBCL CNS, whereas mutations in the PTEN and SMO genes could affect survival regardless of the initial treatment approach. PMID:27164089

  9. Mechanism of generation of large (Ti,Nb,V)(C,N)-type precipitates in H13 + Nb tool steel

    Science.gov (United States)

    Xie, You; Cheng, Guo-guang; Chen, Lie; Zhang, Yan-dong; Yan, Qing-zhong

    2016-11-01

    The characteristics and generation mechanism of (Ti,Nb,V)(C,N) precipitates larger than 2 μm in Nb-containing H13 bar steel were studied. The results show that two types of (Ti,Nb,V)(C,N) phases exist—a Ti-V-rich one and an Nb-rich one—in the form of single or complex precipitates. The sizes of the single Ti-V-rich (Ti,Nb,V)(C,N) precipitates are mostly within 5 to 10 μm, whereas the sizes of the single Nb-rich precipitates are mostly 2-5 μm. The complex precipitates are larger and contain an inner Ti-V-rich layer and an outer Nb-rich layer. The compositional distribution of (Ti,Nb,V)(C,N) is concentrated. The average composition of the single Ti-V-rich phase is (Ti0.511V0.356Nb0.133)(C x N y ), whereas that for the single Nb-rich phase is (Ti0.061V0.263Nb0.676)(C x N y ). The calculation results based on the Scheil-Gulliver model in the Thermo-Calc software combining with the thermal stability experiments show that the large phases precipitate during the solidification process. With the development of solidification, the Ti-V-rich phase precipitates first and becomes homogeneous during the subsequent temperature reduction and heat treatment processes. The Nb-rich phase appears later.

  10. Effect of wind turbine generator model and siting on wind power changes out of large WECS arrays

    Science.gov (United States)

    Schleuter, R. A.; Park, G. L.; Lotfalian, M.; Dorsey, J.; Shayanfar, H.

    1981-01-01

    Methods of reducing the WECS generation change through selection of the wind turbine model for each site, selection of an appropriate siting configuration, and wind array controls are discussed. An analysis of wind generation change from an echelon and a farm for passage of a thunderstorm is presented. Reduction of the wind generation change over ten minutes is shown to reduce the increase in spinning reserve, unloadable generation and load following requirements on unit commitment when significant WECS generation is present and the farm penetration constraint is satisfied. Controls on the blade pitch angle of all wind turbines in an array or a battery control are shown to reduce both the wind generation change out of an array and the effective farm penetration in anticipation of a storm so that the farm penetration constraint may be satisfied.

  11. Energisation of Wind Turbine Transformers with an Auxiliary Generator in a Large Offshore Wind Farm Under Islanded Operation

    DEFF Research Database (Denmark)

    Arana Aristi, Iván; Hernandez, Alvaro; Thumm, Gerhard

    2011-01-01

    of the farm was carried out by an auxiliary diesel-driven synchronous generator placed on the offshore platform. The available information from all of the components and excitation control was implemented in PSCAD-EMTDC. The results from the simulations were compared with the capability curves and current...... limits of the synchronous generator. Based on the worst possible transformer energization scenario, an optimized procedure to reduce the loading of the auxiliary generator during transient conditions has been proposed based on the reduced generator terminal voltage, automatic voltage regulator parameters...

  12. Analysis of Various Inflow Turbulence Generation Methods in Large Eddy Simulation Approach for Prediction of Pollutant Dispersion around Model Buildings

    Directory of Open Access Journals (Sweden)

    F. Bazdidi Tehrani

    2017-02-01

    of windward wall of the second building. Among the various inflow turbulence generation methods, the vortex method is the most precise method and no-inlet perturbation method is the least precise method.

  13. On Matrix Sampling and Imputation of Context Questionnaires with Implications for the Generation of Plausible Values in Large-Scale Assessments

    Science.gov (United States)

    Kaplan, David; Su, Dan

    2016-01-01

    This article presents findings on the consequences of matrix sampling of context questionnaires for the generation of plausible values in large-scale assessments. Three studies are conducted. Study 1 uses data from PISA 2012 to examine several different forms of missing data imputation within the chained equations framework: predictive mean…

  14. The impact of increased interconnection on electricity systems with large penetrations of wind generation: A case study of Ireland and Great Britain

    DEFF Research Database (Denmark)

    Denny, E.; Tuohy, A.; Meibom, Peter

    2010-01-01

    interconnection for the island of Ireland with large penetrations of wind generation. The results suggest that increased interconnection should reduce average prices in Ireland, and the variability of those prices. The simulations also suggest that while increased interconnection may reduce carbon dioxide...

  15. Dynamic performance investigation of once-through-type steam generator for NPP using a large-scale model

    International Nuclear Information System (INIS)

    Kats, F.M.; Ostrovskij, L.A.; Ehskin, N.B.

    1985-01-01

    An experimental bench is described as well as the results of dynamic performance investigation of mass- and heat transfer of the once-through type steam generator for the NPP with weak superheat. Coolant for the primary and secondary circuit is water. Under investigation conditions the possibility of changin.o primary and secondary circuit temperatures has been supphed as well as the primary circuit flow rate and the secondary circuit pressure changes. Transients for differen.t operating conditions are considered. The possibility for construction of the steam generator automatic control system is based

  16. Improvement of the decay heat removal characteristics of the generation IV gas-cooled fast reactor

    International Nuclear Information System (INIS)

    Epiney, A.S.

    2010-01-01

    Gas cooling in nuclear power plants (NPPs) has a long history, the corresponding reactor types developed in France, the UK and the US having been thermal neutron spectrum systems using graphite as the moderator. The majority of NPPs worldwide, however, are currently light water reactors, using ordinary water as both coolant and moderator. These NPPs - of the so-called second generation - will soon need replacement, and a third generation is now being made available, offering increased safety while still based on light water technology. For the longer-term future, viz. beyond the year 2030, R and D is currently ongoing on Generation IV NPPs, aimed at achieving closure of the nuclear fuel cycle, and hence both drastically improved utilization of fuel resources and minimization of long-lived radioactive wastes. Like the SFR, the GFR is an efficient breeder, also able to work as iso-breeder using simply natural uranium as feed and producing waste which is predominantly in the form of fission products. The main drawback of the GFR is the difficulty to evacuate decay heat following a loss-of-coolant accident (LOCA) due to the low thermal inertia of the core, as well as to the low coolant density. The present doctoral research focuses on the improvement of decay heat removal (DHR) for the Generation-IV GFR. The reference GFR system design considered in the thesis is the 2006 CEA concept, with a power of 2400 MWth. The CEA 2006 DHR strategy foresees, in all accidental cases (independent of the system pressure), that the reactor is shut down. For high pressure events, dedicated DHR loops with blowers and heat exchangers are designed to operate when the power conversion system cannot be used to provide acceptable core temperatures under natural convection conditions. For de-pressurized events, the strategy relies on a dedicated small containment (called the guard containment) providing an intermediate back-up pressure. The DHR blowers, designed to work under these pressure

  17. Method for generation of THz frequency radiation and sensing of large amplitude material strain waves in piezoelectric materials

    Science.gov (United States)

    Reed, Evan J.; Armstrong, Michael R.

    2010-09-07

    Strain waves of THz frequencies can coherently generate radiation when they propagate past an interface between materials with different piezoelectric coefficients. Such radiation is of detectable amplitude and contains sufficient information to determine the time-dependence of the strain wave with unprecedented subpicosecond, nearly atomic time and space resolution.

  18. Wind up with continuous intra-day electricity markets? The integration of large-share wind power generation in Denmark

    International Nuclear Information System (INIS)

    Karanfil, Fatih; Li, Yuanjing

    2015-01-01

    This paper suggests an innovative idea to examine the functionality of an electricity intra-day market by testing causality among its fundamental components. As fluctuations of poorly predicted wind power generation are challenging the stability of the current electricity system, an intra-day market design can play an important role in managing wind forecast errors. Using Danish and Nordic data, it investigates the main drivers of the price difference between the intra-day and day-ahead markets, and causality between wind forecast errors and their counterparts. Our results show that the wind and conventional generation forecast errors significantly cause the intra-day price to differ from the day-ahead price, and that the relative intra-day price decreases with the unexpected amount of wind generation. Cross-border electricity exchanges are found to be important to handle wind forecast errors. Additionally, some zonal differences with respect to both causality and impulse responses are detected. This paper provides the first evidence on the persuasive functioning of the intra-day market in the case of Denmark, whereby intermittent production deviations are effectively reduced, and wind forecast errors are jointly handled through the responses from demand, conventional generation, and intra-day international electricity trade. (authors)

  19. Improvement of the decay heat removal characteristics of the generation IV gas-cooled fast reactor

    International Nuclear Information System (INIS)

    Epiney, A. S.

    2010-09-01

    The majority of NPPs worldwide are currently light water reactors, using ordinary water as both coolant and moderator. (...) For the longer-term future, viz. beyond the year 2030, Research and Development is currently ongoing on Generation IV NPPs, aimed at achieving closure of the nuclear fuel cycle, and hence both drastically improved utilization of fuel resources and minimization of long-lived radioactive wastes. Since the very beginning of the international cooperation on Generation IV, viz. the year 2000, the main research interest in Europe as regards the advanced fast-spectrum systems needed for achieving complete fuel cycle closure, has been for the Sodium-cooled Fast Reactor (SFR). However, the Gas-cooled Fast Reactor (GFR) is currently considered as the main back-up solution. Like the SFR, the GFR is an efficient breeder, also able to work as iso-breeder using simply natural uranium as feed and producing waste which is predominantly in the form of fission products. The main drawback of the GFR is the difficulty to evacuate decay heat following a loss-of-coolant accident (LOCA) due to the low thermal inertia of the core, as well as to the low coolant density. The present doctoral research focuses on the improvement of decay heat removal (DHR) for the Generation-IV GFR. The reference GFR system design considered in the thesis is the 2006 CEA concept, with a power of 2400 MWth. The CEA 2006 DHR strategy foresees, in all accidental cases (independent of the system pressure), that the reactor is shut down. For high pressure events, dedicated DHR loops with blowers and heat exchangers are designed to operate when the power conversion system cannot be used to provide acceptable core temperatures under natural convection conditions. For depressurized events, the strategy relies on a dedicated small containment (called the guard containment) providing an intermediate back-up pressure. The DHR blowers, designed to work under these pressure conditions, need to be

  20. Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation.

    Science.gov (United States)

    D'Aiuto, Leonardo; Zhi, Yun; Kumar Das, Dhanjit; Wilcox, Madeleine R; Johnson, Jon W; McClain, Lora; MacDonald, Matthew L; Di Maio, Roberto; Schurdak, Mark E; Piazza, Paolo; Viggiano, Luigi; Sweet, Robert; Kinchington, Paul R; Bhattacharjee, Ayantika G; Yolken, Robert; Nimgaonka, Vishwajit L; Nimgaonkar, Vishwajit L

    2014-01-01

    Induced pluripotent stem cell (iPSC)-based technologies offer an unprecedented opportunity to perform high-throughput screening of novel drugs for neurological and neurodegenerative diseases. Such screenings require a robust and scalable method for generating large numbers of mature, differentiated neuronal cells. Currently available methods based on differentiation of embryoid bodies (EBs) or directed differentiation of adherent culture systems are either expensive or are not scalable. We developed a protocol for large-scale generation of neuronal stem cells (NSCs)/early neural progenitor cells (eNPCs) and their differentiation into neurons. Our scalable protocol allows robust and cost-effective generation of NSCs/eNPCs from iPSCs. Following culture in neurobasal medium supplemented with B27 and BDNF, NSCs/eNPCs differentiate predominantly into vesicular glutamate transporter 1 (VGLUT1) positive neurons. Targeted mass spectrometry analysis demonstrates that iPSC-derived neurons express ligand-gated channels and other synaptic proteins and whole-cell patch-clamp experiments indicate that these channels are functional. The robust and cost-effective differentiation protocol described here for large-scale generation of NSCs/eNPCs and their differentiation into neurons paves the way for automated high-throughput screening of drugs for neurological and neurodegenerative diseases.

  1. Dynamic wave field synthesis: enabling the generation of field distributions with a large space-bandwidth product

    OpenAIRE

    Kamau, Edwin Ngugi

    2016-01-01

    The generation and manipulation of electromagnetic field distributions plays an essential role in physics in general, and particularly in the vast field of physical optics. In the current state of the art, one of the most convenient methods of performing this task is provided by either static or dynamic diffractive as well as holographic optical elements. Currently available dynamic optical elements, such as spatial light modulators, do offer on the one hand high temporal flexibility. They ho...

  2. Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model.

    NARCIS (Netherlands)

    Tatara, A.M.; Kretlow, J.D.; Spicer, P.P.; Lu, S.; Lam, J.; Liu, W.; Cao, Y.; Liu, G.; Jackson, J.D.; Yoo, J.J.; Atala, A.; Beucken, J.J.J.P van den; Jansen, J.A.; Kasper, F.K.; Ho, T.; Demian, N.; Miller, M.J.; Wong, M.E.; Mikos, A.G.

    2015-01-01

    The reconstruction of large craniofacial defects remains a significant clinical challenge. The complex geometry of facial bone and the lack of suitable donor tissue often hinders successful repair. One strategy to address both of these difficulties is the development of an in vivo bioreactor, where

  3. Estimating the electricity prices, generation costs and CO_2 emissions of large scale wind energy exports from Ireland to Great Britain

    International Nuclear Information System (INIS)

    Cleary, Brendan; Duffy, Aidan; Bach, Bjarne; Vitina, Aisma; O’Connor, Alan; Conlon, Michael

    2016-01-01

    The share of wind generation in the Irish and British electricity markets is set to increase by 2020 due to renewable energy (RE) targets. The United Kingdom (UK) and Ireland have set ambitious targets which require 30% and 40% of electricity demand to come from RE, mainly wind, by 2020, respectively. Ireland has sufficient indigenous onshore wind energy resources to exceed the RE target, while the UK faces uncertainty in achieving its target. A possible solution for the UK is to import RE directly from large scale onshore and offshore wind energy projects in Ireland; this possibility has recently been explored by both governments but is currently on hold. Thus, the aim of this paper is to estimate the effects of large scale wind energy in the Irish and British electricity markets in terms of wholesale system marginal prices, total generation costs and CO_2 emissions. The results indicate when the large scale Irish-based wind energy projects are connected directly to the UK there is a decrease of 0.6% and 2% in the Irish and British wholesale system marginal prices under the UK National Grid slow progression scenario, respectively. - Highlights: • Modelling the Irish and British electricity markets. • Investigating the impacts of large scale wind energy within the markets. • Results indicate a reduction in wholesale system marginal prices in both markets. • Decrease in total generation costs and CO_2 emissions in both markets.

  4. Third generation participatory design in health informatics--making user participation applicable to large-scale information system projects.

    Science.gov (United States)

    Pilemalm, Sofie; Timpka, Toomas

    2008-04-01

    Participatory Design (PD) methods in the field of health informatics have mainly been applied to the development of small-scale systems with homogeneous user groups in local settings. Meanwhile, health service organizations are becoming increasingly large and complex in character, making it necessary to extend the scope of the systems that are used for managing data, information and knowledge. This study reports participatory action research on the development of a PD framework for large-scale system design. The research was conducted in a public health informatics project aimed at developing a system for 175,000 users. A renewed PD framework was developed in response to six major limitations experienced to be associated with the existing methods. The resulting framework preserves the theoretical grounding, but extends the toolbox to suit applications in networked health service organizations. Future research should involve evaluations of the framework in other health service settings where comprehensive HISs are developed.

  5. Transcriptome sequencing of lentil based on second-generation technology permits large-scale unigene assembly and SSR marker discovery

    Directory of Open Access Journals (Sweden)

    Materne Michael

    2011-05-01

    Full Text Available Abstract Background Lentil (Lens culinaris Medik. is a cool-season grain legume which provides a rich source of protein for human consumption. In terms of genomic resources, lentil is relatively underdeveloped, in comparison to other Fabaceae species, with limited available data. There is hence a significant need to enhance such resources in order to identify novel genes and alleles for molecular breeding to increase crop productivity and quality. Results Tissue-specific cDNA samples from six distinct lentil genotypes were sequenced using Roche 454 GS-FLX Titanium technology, generating c. 1.38 × 106 expressed sequence tags (ESTs. De novo assembly generated a total of 15,354 contigs and 68,715 singletons. The complete unigene set was sequence-analysed against genome drafts of the model legume species Medicago truncatula and Arabidopsis thaliana to identify 12,639, and 7,476 unique matches, respectively. When compared to the genome of Glycine max, a total of 20,419 unique hits were observed corresponding to c. 31% of the known gene space. A total of 25,592 lentil unigenes were subsequently annoated from GenBank. Simple sequence repeat (SSR-containing ESTs were identified from consensus sequences and a total of 2,393 primer pairs were designed. A subset of 192 EST-SSR markers was screened for validation across a panel 12 cultivated lentil genotypes and one wild relative species. A total of 166 primer pairs obtained successful amplification, of which 47.5% detected genetic polymorphism. Conclusions A substantial collection of ESTs has been developed from sequence analysis of lentil genotypes using second-generation technology, permitting unigene definition across a broad range of functional categories. As well as providing resources for functional genomics studies, the unigene set has permitted significant enhancement of the number of publicly-available molecular genetic markers as tools for improvement of this species.

  6. History of large scale maintenance operations performed by EDF on the steam generators of its nuclear power plants

    International Nuclear Information System (INIS)

    2010-01-01

    After a first part which describes the role of steam generators in nuclear reactors, highlights their importance for the reactor safety, and briefly presents their maintenance, this report describes the new types of degradation which have been observed, and their processing. Thus, it describes the clogging on cracked tubes, comments its impact on safety, describes the available control means, and discusses the use of chemical cleaning and the on-going work on this topic. It discusses the risk of fatigue cracking of tubes in abnormal support position. It comments the holding in position of stoppers used during maintenance. It describes and discusses the corrosion phenomena, and the performed and requested corrective actions

  7. Dynamic wave field synthesis: enabling the generation of field distributions with a large space-bandwidth product.

    Science.gov (United States)

    Kamau, Edwin N; Heine, Julian; Falldorf, Claas; Bergmann, Ralf B

    2015-11-02

    We present a novel approach for the design and fabrication of multiplexed computer generated volume holograms (CGVH) which allow for a dynamic synthesis of arbitrary wave field distributions. To achieve this goal, we developed a hybrid system that consists of a CGVH as a static element and an electronically addressed spatial light modulator as the dynamic element. We thereby derived a new model for describing the scattering process within the inhomogeneous dielectric material of the hologram. This model is based on the linearization of the scattering process within the Rytov approximation and incorporates physical constraints that account for voxel based laser-lithography using micro-fabrication of the holograms in a nonlinear optical material. In this article we demonstrate that this system basically facilitates a high angular Bragg selectivity on the order of 1°. Additionally, it allows for a qualitatively low cross-talk dynamic synthesis of predefined wave fields with a much larger space-bandwidth product (SBWP ≥ 8.7 × 10(6)) as compared to the current state of the art in computer generated holography.

  8. Development and field tests of a damping controller to mitigate electromechanical oscillations on large diesel generating units

    Energy Technology Data Exchange (ETDEWEB)

    Nogueira, Fabricio G.; Barreiros, Jose A.L.; Barra, Walter Jr.; Costa, Carlos T. Jr. [Universidade Federal do Para (UFPA), Instituto de Tecnologia, Faculdade de Engenharia Eletrica, Campus Universitario do Guama, CEP: 66075-900, Belem (Brazil); Ferreira, Andre M.D. [Instituto Federal de Educacao, Ciencia e Tecnologia do Para (IFPA), Campus Belem, Departamento de Controle e Processos Industriais, Av. Almirante Barroso, 1155 (Marco), CEP: 66093-020, Belem (Brazil)

    2011-02-15

    This paper presents the development and field tests of a digital damping controller designed to mitigate intra-plant electromechanical oscillations via the speed governor system of fast acting units. The controller performance is assessed on an 18-MVA diesel generating unit, at Santana Power Plant (Amapa State, Amazon Region at Northern Brazil). In order to design the damping control law, a set of parametric ARX models representing the plant dynamics at several load conditions, are previously identified from data collected on field tests. The damping controller gains are calculated by using the identified ARX models parameters as inputs to a discrete-time pole-placement design method (pole-shifting) and then embedded on a DSP based microcontroller digital system, for field tests assessment. The digital damping controller modulates the diesel engine inlet valve position according to the observed oscillation on the measured electric power, using a PWM device, which is specially developed to this application. The experimental results shown the good performance of the developed controller on damping efficiently the electromechanical oscillations observed between generating units at Santana Power Plant. (author)

  9. Yunnan’s Fast-Paced Large Hydropower Development: A Powershed-Based Approach to Critically Assessing Generation and Consumption Paradigms

    Directory of Open Access Journals (Sweden)

    Thomas Hennig

    2016-10-01

    Full Text Available Southwest China’s Yunnan province is evolving into one of the world’s largest hydro-power-producing regions. It already rivals the world’s largest hydro-producing nations. However, five of Yunnan’s six basins are international and therefore its hydropower development is of great academic and geopolitical interest. While the implementation of large projects on Yunnan’s three large rivers (Jinsha, Mekong and Nu is relatively well studied, hydropower development outside these three main streams is hardly known. Here, we identified 128 large hydropower projects (≥50 MW having a capacity of 16.5 GW, along with another 16.4 GW of other types of power generation, neither of which has been discussed in the academic literature yet. The paper utilizes a powershed approach to study the rapid hydropower development underway in Yunnan, both in its implication and challenges (at basin and administrative level as well as in its trade-offs within the broader electricity context. Yunnan’s power generation and consumption patterns are characterized by diverging interests of local/provincial usage and export utilization. Within the province, the largest (hydro- power users are energy/electricity intensive industries, which themselves have strong impacts on land use changes. Yunnan is also evolving as a major power exporter, already in 2013 exporting about one-third of its generated electricity mainly to Guangdong’s Pearl River Delta. We see a need for a critical revision of those existing generation and consumption paradigms, which includes a rethinking of major development modes, both in terms of future hydropower generation and utilization projects as well as export obligations.

  10. Design of shared instruments to utilize simulated gravities generated by a large-gradient, high-field superconducting magnet.

    Science.gov (United States)

    Wang, Y; Yin, D C; Liu, Y M; Shi, J Z; Lu, H M; Shi, Z H; Qian, A R; Shang, P

    2011-03-01

    A high-field superconducting magnet can provide both high-magnetic fields and large-field gradients, which can be used as a special environment for research or practical applications in materials processing, life science studies, physical and chemical reactions, etc. To make full use of a superconducting magnet, shared instruments (the operating platform, sample holders, temperature controller, and observation system) must be prepared as prerequisites. This paper introduces the design of a set of sample holders and a temperature controller in detail with an emphasis on validating the performance of the force and temperature sensors in the high-magnetic field.

  11. Neutrinoless double-β decay matrix elements in large shell-model spaces with the generator-coordinate method

    Science.gov (United States)

    Jiao, C. F.; Engel, J.; Holt, J. D.

    2017-11-01

    We use the generator-coordinate method (GCM) with realistic shell-model interactions to closely approximate full shell-model calculations of the matrix elements for the neutrinoless double-β decay of 48Ca, 76Ge, and 82Se. We work in one major shell for the first isotope, in the f5 /2p g9 /2 space for the second and third, and finally in two major shells for all three. Our coordinates include not only the usual axial deformation parameter β , but also the triaxiality angle γ and neutron-proton pairing amplitudes. In the smaller model spaces our matrix elements agree well with those of full shell-model diagonalization, suggesting that our Hamiltonian-based GCM captures most of the important valence-space correlations. In two major shells, where exact diagonalization is not currently possible, our matrix elements are only slightly different from those in a single shell.

  12. ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider

    CERN Document Server

    Aad, Georges; Abdallah, Jalal; Abdinov, Ovsat; Aben, Rosemarie; Abolins, Maris; AbouZeid, Ossama; Abramowicz, Halina; Abreu, Henso; Abreu, Ricardo; Abulaiti, Yiming; Acharya, Bobby Samir; Adamczyk, Leszek; Adams, David; Adelman, Jahred; Adomeit, Stefanie; Adye, Tim; Affolder, Tony; Agatonovic-Jovin, Tatjana; Agricola, Johannes; Aguilar-Saavedra, Juan Antonio; Ahlen, Steven; Ahmadov, Faig; Aielli, Giulio; Akerstedt, Henrik; Åkesson, Torsten Paul Ake; Akimov, Andrei; Alberghi, Gian Luigi; Albert, Justin; Albrand, Solveig; Alconada Verzini, Maria Josefina; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexopoulos, Theodoros; Alhroob, Muhammad; Alimonti, Gianluca; Alio, Lion; Alison, John; Alkire, Steven Patrick; Allbrooke, Benedict; Allport, Phillip; Aloisio, Alberto; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Altheimer, Andrew David; Alvarez Gonzalez, Barbara; Άlvarez Piqueras, Damián; Alviggi, Mariagrazia; Amadio, Brian Thomas; Amako, Katsuya; Amaral Coutinho, Yara; Amelung, Christoph; Amidei, Dante; Amor Dos Santos, Susana Patricia; Amorim, Antonio; Amoroso, Simone; Amram, Nir; Amundsen, Glenn; Anastopoulos, Christos; Ancu, Lucian Stefan; Andari, Nansi; Andeen, Timothy; Anders, Christoph Falk; Anders, Gabriel; Anders, John Kenneth; Anderson, Kelby; Andreazza, Attilio; Andrei, George Victor; Angelidakis, Stylianos; Angelozzi, Ivan; Anger, Philipp; Angerami, Aaron; Anghinolfi, Francis; Anisenkov, Alexey; Anjos, Nuno; Annovi, Alberto; Antonelli, Mario; Antonov, Alexey; Antos, Jaroslav; Anulli, Fabio; Aoki, Masato; Aperio Bella, Ludovica; Arabidze, Giorgi; Arai, Yasuo; Araque, Juan Pedro; Arce, Ayana; Arduh, Francisco Anuar; Arguin, Jean-Francois; Argyropoulos, Spyridon; Arik, Metin; Armbruster, Aaron James; Arnaez, Olivier; Arnal, Vanessa; Arnold, Hannah; Arratia, Miguel; Arslan, Ozan; Artamonov, Andrei; Artoni, Giacomo; Asai, Shoji; Asbah, Nedaa; Ashkenazi, Adi; Åsman, Barbro; Asquith, Lily; Assamagan, Ketevi; Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Auerbach, Benjamin; Augsten, Kamil; Aurousseau, Mathieu; Avolio, Giuseppe; Axen, Bradley; Ayoub, Mohamad Kassem; Azuelos, Georges; Baak, Max; Baas, Alessandra; Baca, Matthew John; Bacci, Cesare; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Backhaus, Malte; Bagiacchi, Paolo; Bagnaia, Paolo; Bai, Yu; Bain, Travis; Baines, John; Baker, Oliver Keith; Baldin, Evgenii; Balek, Petr; Balestri, Thomas; Balli, Fabrice; Banas, Elzbieta; Banerjee, Swagato; Bannoura, Arwa A E; Bansil, Hardeep Singh; Barak, Liron; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisonzi, Marcello; Barklow, Timothy; Barlow, Nick; Barnes, Sarah Louise; Barnett, Bruce; Barnett, Michael; Barnovska, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Basalaev, Artem; Bassalat, Ahmed; Basye, Austin; Bates, Richard; Batista, Santiago Juan; Batley, Richard; Battaglia, Marco; Bauce, Matteo; Bauer, Florian; Bawa, Harinder Singh; Beacham, James Baker; Beattie, Michael David; Beau, Tristan; Beauchemin, Pierre-Hugues; Beccherle, Roberto; Bechtle, Philip; Beck, Hans Peter; Becker, Kathrin; Becker, Maurice; Becker, Sebastian; Beckingham, Matthew; Becot, Cyril; Beddall, Andrew; Beddall, Ayda; Bednyakov, Vadim; Bee, Christopher; Beemster, Lars; Beermann, Thomas; Begel, Michael; Behr, Janna Katharina; Belanger-Champagne, Camille; Bell, William; Bella, Gideon; Bellagamba, Lorenzo; Bellerive, Alain; Bellomo, Massimiliano; Belotskiy, Konstantin; Beltramello, Olga; Benary, Odette; Benchekroun, Driss; Bender, Michael; Bendtz, Katarina; Benekos, Nektarios; Benhammou, Yan; Benhar Noccioli, Eleonora; Benitez Garcia, Jorge-Armando; Benjamin, Douglas; Bensinger, James; Bentvelsen, Stan; Beresford, Lydia; Beretta, Matteo; Berge, David; Bergeaas Kuutmann, Elin; Berger, Nicolas; Berghaus, Frank; Beringer, Jürg; Bernard, Clare; Bernard, Nathan Rogers; Bernius, Catrin; Bernlochner, Florian Urs; Berry, Tracey; Berta, Peter; Bertella, Claudia; Bertoli, Gabriele; Bertolucci, Federico; Bertsche, Carolyn; Bertsche, David; Besana, Maria Ilaria; Besjes, Geert-Jan; Bessidskaia Bylund, Olga; Bessner, Martin Florian; Besson, Nathalie; Betancourt, Christopher; Bethke, Siegfried; Bevan, Adrian John; Bhimji, Wahid; Bianchi, Riccardo-Maria; Bianchini, Louis; Bianco, Michele; Biebel, Otmar; Biedermann, Dustin; Bieniek, Stephen Paul; Biglietti, Michela; Bilbao De Mendizabal, Javier; Bilokon, Halina; Bindi, Marcello; Binet, Sebastien; Bingul, Ahmet; Bini, Cesare; Biondi, Silvia; Black, Curtis; Black, James; Black, Kevin; Blackburn, Daniel; Blair, Robert; Blanchard, Jean-Baptiste; Blanco, Jacobo Ezequiel; Blazek, Tomas; Bloch, Ingo; Blocker, Craig; Blum, Walter; Blumenschein, Ulrike; Bobbink, Gerjan; Bobrovnikov, Victor; Bocchetta, Simona Serena; Bocci, Andrea; Bock, Christopher; Boehler, Michael; Bogaerts, Joannes Andreas; Bogavac, Danijela; Bogdanchikov, Alexander; Bohm, Christian; Boisvert, Veronique; Bold, Tomasz; Boldea, Venera; Boldyrev, Alexey; Bomben, Marco; Bona, Marcella; Boonekamp, Maarten; Borisov, Anatoly; Borissov, Guennadi; Borroni, Sara; Bortfeldt, Jonathan; Bortolotto, Valerio; Bos, Kors; Boscherini, Davide; Bosman, Martine; Boudreau, Joseph; Bouffard, Julian; Bouhova-Thacker, Evelina Vassileva; Boumediene, Djamel Eddine; Bourdarios, Claire; Bousson, Nicolas; Boveia, Antonio; Boyd, James; Boyko, Igor; Bozic, Ivan; Bracinik, Juraj; Brandt, Andrew; Brandt, Gerhard; Brandt, Oleg; Bratzler, Uwe; Brau, Benjamin; Brau, James; Braun, Helmut; Brazzale, Simone Federico; Breaden Madden, William Dmitri; Brendlinger, Kurt; Brennan, Amelia Jean; Brenner, Lydia; Brenner, Richard; Bressler, Shikma; Bristow, Kieran; Bristow, Timothy Michael; Britton, Dave; Britzger, Daniel; Brochu, Frederic; Brock, Ian; Brock, Raymond; Bronner, Johanna; Brooijmans, Gustaaf; Brooks, Timothy; Brooks, William; Brosamer, Jacquelyn; Brost, Elizabeth; Brown, Jonathan; Bruckman de Renstrom, Pawel; Bruncko, Dusan; Bruneliere, Renaud; Bruni, Alessia; Bruni, Graziano; Bruschi, Marco; Bruscino, Nello; Bryngemark, Lene; Buanes, Trygve; Buat, Quentin; Buchholz, Peter; Buckley, Andrew; Buda, Stelian Ioan; Budagov, Ioulian; Buehrer, Felix; Bugge, Lars; Bugge, Magnar Kopangen; Bulekov, Oleg; Bullock, Daniel; Burckhart, Helfried; Burdin, Sergey; Burghgrave, Blake; Burke, Stephen; Burmeister, Ingo; Busato, Emmanuel; Büscher, Daniel; Büscher, Volker; Bussey, Peter; Butler, John; Butt, Aatif Imtiaz; Buttar, Craig; Butterworth, Jonathan; Butti, Pierfrancesco; Buttinger, William; Buzatu, Adrian; Buzykaev, Aleksey; Cabrera Urbán, Susana; Caforio, Davide; Cairo, Valentina; Cakir, Orhan; Calace, Noemi; Calafiura, Paolo; Calandri, Alessandro; Calderini, Giovanni; Calfayan, Philippe; Caloba, Luiz; Calvet, David; Calvet, Samuel; Camacho Toro, Reina; Camarda, Stefano; Camarri, Paolo; Cameron, David; Caminal Armadans, Roger; Campana, Simone; Campanelli, Mario; Campoverde, Angel; Canale, Vincenzo; Canepa, Anadi; Cano Bret, Marc; Cantero, Josu; Cantrill, Robert; Cao, Tingting; Capeans Garrido, Maria Del Mar; Caprini, Irinel; Caprini, Mihai; Capua, Marcella; Caputo, Regina; Cardarelli, Roberto; Cardillo, Fabio; Carli, Tancredi; Carlino, Gianpaolo; Carminati, Leonardo; Caron, Sascha; Carquin, Edson; Carrillo-Montoya, German D; Carter, Janet; Carvalho, João; Casadei, Diego; Casado, Maria Pilar; Casolino, Mirkoantonio; Castaneda-Miranda, Elizabeth; Castelli, Angelantonio; Castillo Gimenez, Victoria; Castro, Nuno Filipe; Catastini, Pierluigi; Catinaccio, Andrea; Catmore, James; Cattai, Ariella; Caudron, Julien; Cavaliere, Viviana; Cavalli, Donatella; Cavalli-Sforza, Matteo; Cavasinni, Vincenzo; Ceradini, Filippo; Cerio, Benjamin; Cerny, Karel; Santiago Cerqueira, Augusto; Cerri, Alessandro; Cerrito, Lucio; Cerutti, Fabio; Cerv, Matevz; Cervelli, Alberto; Cetin, Serkant Ali; Chafaq, Aziz; Chakraborty, Dhiman; Chalupkova, Ina; Chang, Philip; Chapman, John Derek; Charlton, Dave; Chau, Chav Chhiv; Chavez Barajas, Carlos Alberto; Cheatham, Susan; Chegwidden, Andrew; Chekanov, Sergei; Chekulaev, Sergey; Chelkov, Gueorgui; Chelstowska, Magda Anna; Chen, Chunhui; Chen, Hucheng; Chen, Karen; Chen, Liming; Chen, Shenjian; Chen, Xin; Chen, Ye; Cheng, Hok Chuen; Cheng, Yangyang; Cheplakov, Alexander; Cheremushkina, Evgenia; Cherkaoui El Moursli, Rajaa; Chernyatin, Valeriy; Cheu, Elliott; Chevalier, Laurent; Chiarella, Vitaliano; Chiarelli, Giorgio; Childers, John Taylor; Chiodini, Gabriele; Chisholm, Andrew; Chislett, Rebecca Thalatta; Chitan, Adrian; Chizhov, Mihail; Choi, Kyungeon; Chouridou, Sofia; Chow, Bonnie Kar Bo; Christodoulou, Valentinos; Chromek-Burckhart, Doris; Chudoba, Jiri; Chuinard, Annabelle Julia; Chwastowski, Janusz; Chytka, Ladislav; Ciapetti, Guido; Ciftci, Abbas Kenan; Cinca, Diane; Cindro, Vladimir; Cioara, Irina Antonela; Ciocio, Alessandra; Citron, Zvi Hirsh; Ciubancan, Mihai; Clark, Allan G; Clark, Brian Lee; Clark, Philip James; Clarke, Robert; Cleland, Bill; Clement, Christophe; Coadou, Yann; Cobal, Marina; Coccaro, Andrea; Cochran, James H; Coffey, Laurel; Cogan, Joshua Godfrey; Colasurdo, Luca; Cole, Brian; Cole, Stephen; Colijn, Auke-Pieter; Collot, Johann; Colombo, Tommaso; Compostella, Gabriele; Conde Muiño, Patricia; Coniavitis, Elias; Connell, Simon Henry; Connelly, Ian; Consonni, Sofia Maria; Consorti, Valerio; Constantinescu, Serban; Conta, Claudio; Conti, Geraldine; Conventi, Francesco; Cooke, Mark; Cooper, Ben; Cooper-Sarkar, Amanda; Cornelissen, Thijs; Corradi, Massimo; Corriveau, Francois; Corso-Radu, Alina; Cortes-Gonzalez, Arely; Cortiana, Giorgio; Costa, Giuseppe; Costa, María José; Costanzo, Davide; Côté, David; Cottin, Giovanna; Cowan, Glen; Cox, Brian; Cranmer, Kyle; Cree, Graham; Crépé-Renaudin, Sabine; Crescioli, Francesco; Cribbs, Wayne Allen; Crispin Ortuzar, Mireia; Cristinziani, Markus; Croft, Vince; Crosetti, Giovanni; Cuhadar Donszelmann, Tulay; Cummings, Jane; Curatolo, Maria; Cuthbert, Cameron; Czirr, Hendrik; Czodrowski, Patrick; D'Auria, Saverio; D'Onofrio, Monica; Da Cunha Sargedas De Sousa, Mario Jose; Da Via, Cinzia; Dabrowski, Wladyslaw; Dafinca, Alexandru; Dai, Tiesheng; Dale, Orjan; Dallaire, Frederick; Dallapiccola, Carlo; Dam, Mogens; Dandoy, Jeffrey Rogers; Dang, Nguyen Phuong; Daniells, Andrew Christopher; Danninger, Matthias; Dano Hoffmann, Maria; Dao, Valerio; Darbo, Giovanni; Darmora, Smita; Dassoulas, James; Dattagupta, Aparajita; Davey, Will; David, Claire; Davidek, Tomas; Davies, Eleanor; Davies, Merlin; Davison, Peter; Davygora, Yuriy; Dawe, Edmund; Dawson, Ian; Daya-Ishmukhametova, Rozmin; De, Kaushik; de Asmundis, Riccardo; De Benedetti, Abraham; De Castro, Stefano; De Cecco, Sandro; De Groot, Nicolo; de Jong, Paul; De la Torre, Hector; De Lorenzi, Francesco; De Nooij, Lucie; De Pedis, Daniele; De Salvo, Alessandro; De Sanctis, Umberto; De Santo, Antonella; De Vivie De Regie, Jean-Baptiste; Dearnaley, William James; Debbe, Ramiro; Debenedetti, Chiara; Dedovich, Dmitri; Deigaard, Ingrid; Del Peso, Jose; Del Prete, Tarcisio; Delgove, David; Deliot, Frederic; Delitzsch, Chris Malena; Deliyergiyev, Maksym; Dell'Acqua, Andrea; Dell'Asta, Lidia; Dell'Orso, Mauro; Della Pietra, Massimo; della Volpe, Domenico; Delmastro, Marco; Delsart, Pierre-Antoine; Deluca, Carolina; DeMarco, David; Demers, Sarah; Demichev, Mikhail; Demilly, Aurelien; Denisov, Sergey; Derendarz, Dominik; Derkaoui, Jamal Eddine; Derue, Frederic; Dervan, Paul; Desch, Klaus Kurt; Deterre, Cecile; Deviveiros, Pier-Olivier; Dewhurst, Alastair; Dhaliwal, Saminder; Di Ciaccio, Anna; Di Ciaccio, Lucia; Di Domenico, Antonio; Di Donato, Camilla; Di Girolamo, Alessandro; Di Girolamo, Beniamino; Di Mattia, Alessandro; Di Micco, Biagio; Di Nardo, Roberto; Di Simone, Andrea; Di Sipio, Riccardo; Di Valentino, David; Diaconu, Cristinel; Diamond, Miriam; Dias, Flavia; Diaz, Marco Aurelio; Diehl, Edward; Dietrich, Janet; Diglio, Sara; Dimitrievska, Aleksandra; Dingfelder, Jochen; Dita, Petre; Dita, Sanda; Dittus, Fridolin; Djama, Fares; Djobava, Tamar; Djuvsland, Julia Isabell; Barros do Vale, Maria Aline; Dobos, Daniel; Dobre, Monica; Doglioni, Caterina; Dohmae, Takeshi; Dolejsi, Jiri; Dolezal, Zdenek; Dolgoshein, Boris; Donadelli, Marisilvia; Donati, Simone; Dondero, Paolo; Donini, Julien; Dopke, Jens; Doria, Alessandra; Dova, Maria-Teresa; Doyle, Tony; Drechsler, Eric; Dris, Manolis; Dubreuil, Emmanuelle; Duchovni, Ehud; Duckeck, Guenter; Ducu, Otilia Anamaria; Duda, Dominik; Dudarev, Alexey; Duflot, Laurent; Duguid, Liam; Dührssen, Michael; Dunford, Monica; Duran Yildiz, Hatice; Düren, Michael; Durglishvili, Archil; Duschinger, Dirk; Dyndal, Mateusz; Eckardt, Christoph; Ecker, Katharina Maria; Edgar, Ryan Christopher; Edson, William; Edwards, Nicholas Charles; Ehrenfeld, Wolfgang; Eifert, Till; Eigen, Gerald; Einsweiler, Kevin; Ekelof, Tord; El Kacimi, Mohamed; Ellert, Mattias; Elles, Sabine; Ellinghaus, Frank; Elliot, Alison; Ellis, Nicolas; Elmsheuser, Johannes; Elsing, Markus; Emeliyanov, Dmitry; Enari, Yuji; Endner, Oliver Chris; Endo, Masaki; Erdmann, Johannes; Ereditato, Antonio; Ernis, Gunar; Ernst, Jesse; Ernst, Michael; Errede, Steven; Ertel, Eugen; Escalier, Marc; Esch, Hendrik; Escobar, Carlos; Esposito, Bellisario; Etienvre, Anne-Isabelle; Etzion, Erez; Evans, Hal; Ezhilov, Alexey; Fabbri, Laura; Facini, Gabriel; Fakhrutdinov, Rinat; Falciano, Speranza; Falla, Rebecca Jane; Faltova, Jana; Fang, Yaquan; Fanti, Marcello; Farbin, Amir; Farilla, Addolorata; Farooque, Trisha; Farrell, Steven; Farrington, Sinead; Farthouat, Philippe; Fassi, Farida; Fassnacht, Patrick; Fassouliotis, Dimitrios; Faucci Giannelli, Michele; Favareto, Andrea; Fayard, Louis; Federic, Pavol; Fedin, Oleg; Fedorko, Wojciech; Feigl, Simon; Feligioni, Lorenzo; Feng, Cunfeng; Feng, Eric; Feng, Haolu; Fenyuk, Alexander; Feremenga, Last; Fernandez Martinez, Patricia; Fernandez Perez, Sonia; Ferrando, James; Ferrari, Arnaud; Ferrari, Pamela; Ferrari, Roberto; Ferreira de Lima, Danilo Enoque; Ferrer, Antonio; Ferrere, Didier; Ferretti, Claudio; Ferretto Parodi, Andrea; Fiascaris, Maria; Fiedler, Frank; Filipčič, Andrej; Filipuzzi, Marco; Filthaut, Frank; Fincke-Keeler, Margret; Finelli, Kevin Daniel; Fiolhais, Miguel; Fiorini, Luca; Firan, Ana; Fischer, Adam; Fischer, Cora; Fischer, Julia; Fisher, Wade Cameron; Fitzgerald, Eric Andrew; Flaschel, Nils; Fleck, Ivor; Fleischmann, Philipp; Fleischmann, Sebastian; Fletcher, Gareth Thomas; Fletcher, Gregory; Fletcher, Rob Roy MacGregor; Flick, Tobias; Floderus, Anders; Flores Castillo, Luis; Flowerdew, Michael; Formica, Andrea; Forti, Alessandra; Fournier, Daniel; Fox, Harald; Fracchia, Silvia; Francavilla, Paolo; Franchini, Matteo; Francis, David; Franconi, Laura; Franklin, Melissa; Frate, Meghan; Fraternali, Marco; Freeborn, David; French, Sky; Friedrich, Felix; Froidevaux, Daniel; Frost, James; Fukunaga, Chikara; Fullana Torregrosa, Esteban; Fulsom, Bryan Gregory; Fusayasu, Takahiro; Fuster, Juan; Gabaldon, Carolina; Gabizon, Ofir; Gabrielli, Alessandro; Gabrielli, Andrea; Gach, Grzegorz; Gadatsch, Stefan; Gadomski, Szymon; Gagliardi, Guido; Gagnon, Pauline; Galea, Cristina; Galhardo, Bruno; Gallas, Elizabeth; Gallop, Bruce; Gallus, Petr; Galster, Gorm Aske Gram Krohn; Gan, KK; Gao, Jun; Gao, Yanyan; Gao, Yongsheng; Garay Walls, Francisca; Garberson, Ford; García, Carmen; García Navarro, José Enrique; Garcia-Sciveres, Maurice; Gardner, Robert; Garelli, Nicoletta; Garonne, Vincent; Gatti, Claudio; Gaudiello, Andrea; Gaudio, Gabriella; Gaur, Bakul; Gauthier, Lea; Gauzzi, Paolo; Gavrilenko, Igor; Gay, Colin; Gaycken, Goetz; Gazis, Evangelos; Ge, Peng; Gecse, Zoltan; Gee, Norman; Geerts, Daniël Alphonsus Adrianus; Geich-Gimbel, Christoph; Geisler, Manuel Patrice; Gemme, Claudia; Genest, Marie-Hélène; Gentile, Simonetta; George, Matthias; George, Simon; Gerbaudo, Davide; Gershon, Avi; Ghasemi, Sara; Ghazlane, Hamid; Giacobbe, Benedetto; Giagu, Stefano; Giangiobbe, Vincent; Giannetti, Paola; Gibbard, Bruce; Gibson, Stephen; Gilchriese, Murdock; Gillam, Thomas; Gillberg, Dag; Gilles, Geoffrey; Gingrich, Douglas; Giokaris, Nikos; Giordani, MarioPaolo; Giorgi, Filippo Maria; Giorgi, Francesco Michelangelo; Giraud, Pierre-Francois; Giromini, Paolo; Giugni, Danilo; Giuliani, Claudia; Giulini, Maddalena; Gjelsten, Børge Kile; Gkaitatzis, Stamatios; Gkialas, Ioannis; Gkougkousis, Evangelos Leonidas; Gladilin, Leonid; Glasman, Claudia; Glatzer, Julian; Glaysher, Paul; Glazov, Alexandre; Goblirsch-Kolb, Maximilian; Goddard, Jack Robert; Godlewski, Jan; Goldfarb, Steven; Golling, Tobias; Golubkov, Dmitry; Gomes, Agostinho; Gonçalo, Ricardo; Goncalves Pinto Firmino Da Costa, Joao; Gonella, Laura; González de la Hoz, Santiago; Gonzalez Parra, Garoe; Gonzalez-Sevilla, Sergio; Goossens, Luc; Gorbounov, Petr Andreevich; Gordon, Howard; Gorelov, Igor; Gorini, Benedetto; Gorini, Edoardo; Gorišek, Andrej; Gornicki, Edward; Goshaw, Alfred; Gössling, Claus; Gostkin, Mikhail Ivanovitch; Goujdami, Driss; Goussiou, Anna; Govender, Nicolin; Gozani, Eitan; Grabas, Herve Marie Xavier; Graber, Lars; Grabowska-Bold, Iwona; Gradin, Per Olov Joakim; Grafström, Per; Grahn, Karl-Johan; Gramling, Johanna; Gramstad, Eirik; Grancagnolo, Sergio; Grassi, Valerio; Gratchev, Vadim; Gray, Heather; Graziani, Enrico; Greenwood, Zeno Dixon; Gregersen, Kristian; Gregor, Ingrid-Maria; Grenier, Philippe; Griffiths, Justin; Grillo, Alexander; Grimm, Kathryn; Grinstein, Sebastian; Gris, Philippe Luc Yves; Grivaz, Jean-Francois; Grohs, Johannes Philipp; Grohsjean, Alexander; Gross, Eilam; Grosse-Knetter, Joern; Grossi, Giulio Cornelio; Grout, Zara Jane; Guan, Liang; Guenther, Jaroslav; Guescini, Francesco; Guest, Daniel; Gueta, Orel; Guido, Elisa; Guillemin, Thibault; Guindon, Stefan; Gul, Umar; Gumpert, Christian; Guo, Jun; Guo, Yicheng; Gupta, Shaun; Gustavino, Giuliano; Gutierrez, Phillip; Gutierrez Ortiz, Nicolas Gilberto; Gutschow, Christian; Guyot, Claude; Gwenlan, Claire; Gwilliam, Carl; Haas, Andy; Haber, Carl; Hadavand, Haleh Khani; Haddad, Nacim; Haefner, Petra; Hageböck, Stephan; Hajduk, Zbigniew; Hakobyan, Hrachya; Haleem, Mahsana; Haley, Joseph; Hall, David; Halladjian, Garabed; Hallewell, Gregory David; Hamacher, Klaus; Hamal, Petr; Hamano, Kenji; Hamer, Matthias; Hamilton, Andrew; Hamity, Guillermo Nicolas; Hamnett, Phillip George; Han, Liang; Hanagaki, Kazunori; Hanawa, Keita; Hance, Michael; Hanke, Paul; Hanna, Remie; Hansen, Jørgen Beck; Hansen, Jorn Dines; Hansen, Maike Christina; Hansen, Peter Henrik; Hara, Kazuhiko; Hard, Andrew; Harenberg, Torsten; Hariri, Faten; Harkusha, Siarhei; Harrington, Robert; Harrison, Paul Fraser; Hartjes, Fred; Hasegawa, Makoto; Hasegawa, Satoshi; Hasegawa, Yoji; Hasib, A; Hassani, Samira; Haug, Sigve; Hauser, Reiner; Hauswald, Lorenz; Havranek, Miroslav; Hawkes, Christopher; Hawkings, Richard John; Hawkins, Anthony David; Hayashi, Takayasu; Hayden, Daniel; Hays, Chris; Hays, Jonathan Michael; Hayward, Helen; Haywood, Stephen; Head, Simon; Heck, Tobias; Hedberg, Vincent; Heelan, Louise; Heim, Sarah; Heim, Timon; Heinemann, Beate; Heinrich, Lukas; Hejbal, Jiri; Helary, Louis; Hellman, Sten; Hellmich, Dennis; Helsens, Clement; Henderson, James; Henderson, Robert; Heng, Yang; Hengler, Christopher; Henrichs, Anna; Henriques Correia, Ana Maria; Henrot-Versille, Sophie; Herbert, Geoffrey Henry; Hernández Jiménez, Yesenia; Herrberg-Schubert, Ruth; Herten, Gregor; Hertenberger, Ralf; Hervas, Luis; Hesketh, Gavin Grant; Hessey, Nigel; Hetherly, Jeffrey Wayne; Hickling, Robert; Higón-Rodriguez, Emilio; Hill, Ewan; Hill, John; Hiller, Karl Heinz; Hillier, Stephen; Hinchliffe, Ian; Hines, Elizabeth; Hinman, Rachel Reisner; Hirose, Minoru; Hirschbuehl, Dominic; Hobbs, John; Hod, Noam; Hodgkinson, Mark; Hodgson, Paul; Hoecker, Andreas; Hoeferkamp, Martin; Hoenig, Friedrich; Hohlfeld, Marc; Hohn, David; Holmes, Tova Ray; Homann, Michael; Hong, Tae Min; Hooft van Huysduynen, Loek; Hopkins, Walter; Horii, Yasuyuki; Horton, Arthur James; Hostachy, Jean-Yves; Hou, Suen; Hoummada, Abdeslam; Howard, Jacob; Howarth, James; Hrabovsky, Miroslav; Hristova, Ivana; Hrivnac, Julius; Hryn'ova, Tetiana; Hrynevich, Aliaksei; Hsu, Catherine; Hsu, Pai-hsien Jennifer; Hsu, Shih-Chieh; Hu, Diedi; Hu, Qipeng; Hu, Xueye; Huang, Yanping; Hubacek, Zdenek; Hubaut, Fabrice; Huegging, Fabian; Huffman, Todd Brian; Hughes, Emlyn; Hughes, Gareth; Huhtinen, Mika; Hülsing, Tobias Alexander; Huseynov, Nazim; Huston, Joey; Huth, John; Iacobucci, Giuseppe; Iakovidis, Georgios; Ibragimov, Iskander; Iconomidou-Fayard, Lydia; Ideal, Emma; Idrissi, Zineb; Iengo, Paolo; Igonkina, Olga; Iizawa, Tomoya; Ikegami, Yoichi; Ikematsu, Katsumasa; Ikeno, Masahiro; Ilchenko, Iurii; Iliadis, Dimitrios; Ilic, Nikolina; Ince, Tayfun; Introzzi, Gianluca; Ioannou, Pavlos; Iodice, Mauro; Iordanidou, Kalliopi; Ippolito, Valerio; Irles Quiles, Adrian; Isaksson, Charlie; Ishino, Masaya; Ishitsuka, Masaki; Ishmukhametov, Renat; Issever, Cigdem; Istin, Serhat; Iturbe Ponce, Julia Mariana; Iuppa, Roberto; Ivarsson, Jenny; Iwanski, Wieslaw; Iwasaki, Hiroyuki; Izen, Joseph; Izzo, Vincenzo; Jabbar, Samina; Jackson, Brett; Jackson, Matthew; Jackson, Paul; Jaekel, Martin; Jain, Vivek; Jakobs, Karl; Jakobsen, Sune; Jakoubek, Tomas; Jakubek, Jan; Jamin, David Olivier; Jana, Dilip; Jansen, Eric; Jansky, Roland; Janssen, Jens; Janus, Michel; Jarlskog, Göran; Javadov, Namig; Javůrek, Tomáš; Jeanty, Laura; Jejelava, Juansher; Jeng, Geng-yuan; Jennens, David; Jenni, Peter; Jentzsch, Jennifer; Jeske, Carl; Jézéquel, Stéphane; Ji, Haoshuang; Jia, Jiangyong; Jiang, Yi; Jiggins, Stephen; Jimenez Pena, Javier; Jin, Shan; Jinaru, Adam; Jinnouchi, Osamu; Joergensen, Morten Dam; Johansson, Per; Johns, Kenneth; Jon-And, Kerstin; Jones, Graham; Jones, Roger; Jones, Tim; Jongmanns, Jan; Jorge, Pedro; Joshi, Kiran Daniel; Jovicevic, Jelena; Ju, Xiangyang; Jung, Christian; Jussel, Patrick; Juste Rozas, Aurelio; Kaci, Mohammed; Kaczmarska, Anna; Kado, Marumi; Kagan, Harris; Kagan, Michael; Kahn, Sebastien Jonathan; Kajomovitz, Enrique; Kalderon, Charles William; Kama, Sami; Kamenshchikov, Andrey; Kanaya, Naoko; Kaneti, Steven; Kantserov, Vadim; Kanzaki, Junichi; Kaplan, Benjamin; Kaplan, Laser Seymour; Kapliy, Anton; Kar, Deepak; Karakostas, Konstantinos; Karamaoun, Andrew; Karastathis, Nikolaos; Kareem, Mohammad Jawad; Karentzos, Efstathios; Karnevskiy, Mikhail; Karpov, Sergey; Karpova, Zoya; Karthik, Krishnaiyengar; Kartvelishvili, Vakhtang; Karyukhin, Andrey; Kashif, Lashkar; Kass, Richard; Kastanas, Alex; Kataoka, Yousuke; Katre, Akshay; Katzy, Judith; Kawagoe, Kiyotomo; Kawamoto, Tatsuo; Kawamura, Gen; Kazama, Shingo; Kazanin, Vassili; Keeler, Richard; Kehoe, Robert; Keller, John; Kempster, Jacob Julian; Keoshkerian, Houry; Kepka, Oldrich; Kerševan, Borut Paul; Kersten, Susanne; Keyes, Robert; Khalil-zada, Farkhad; Khandanyan, Hovhannes; Khanov, Alexander; Kharlamov, Alexey; Khoo, Teng Jian; Khovanskiy, Valery; Khramov, Evgeniy; Khubua, Jemal; Kim, Hee Yeun; Kim, Hyeon Jin; Kim, Shinhong; Kim, Young-Kee; Kimura, Naoki; Kind, Oliver Maria; King, Barry; King, Matthew; King, Samuel Burton; Kirk, Julie; Kiryunin, Andrey; Kishimoto, Tomoe; Kisielewska, Danuta; Kiss, Florian; Kiuchi, Kenji; Kivernyk, Oleh; Kladiva, Eduard; Klein, Matthew Henry; Klein, Max; Klein, Uta; Kleinknecht, Konrad; Klimek, Pawel; Klimentov, Alexei; Klingenberg, Reiner; Klinger, Joel Alexander; Klioutchnikova, Tatiana; Kluge, Eike-Erik; Kluit, Peter; Kluth, Stefan; Knapik, Joanna; Kneringer, Emmerich; Knoops, Edith; Knue, Andrea; Kobayashi, Aine; Kobayashi, Dai; Kobayashi, Tomio; Kobel, Michael; Kocian, Martin; Kodys, Peter; Koffas, Thomas; Koffeman, Els; Kogan, Lucy Anne; Kohlmann, Simon; Kohout, Zdenek; Kohriki, Takashi; Koi, Tatsumi; Kolanoski, Hermann; Koletsou, Iro; Komar, Aston; Komori, Yuto; Kondo, Takahiko; Kondrashova, Nataliia; Köneke, Karsten; König, Adriaan; Kono, Takanori; Konoplich, Rostislav; Konstantinidis, Nikolaos; Kopeliansky, Revital; Koperny, Stefan; Köpke, Lutz; Kopp, Anna Katharina; Korcyl, Krzysztof; Kordas, Kostantinos; Korn, Andreas; Korol, Aleksandr; Korolkov, Ilya; Korolkova, Elena; Kortner, Oliver; Kortner, Sandra; Kosek, Tomas; Kostyukhin, Vadim; Kotov, Vladislav; Kotwal, Ashutosh; Kourkoumeli-Charalampidi, Athina; Kourkoumelis, Christine; Kouskoura, Vasiliki; Koutsman, Alex; Kowalewski, Robert Victor; Kowalski, Tadeusz; Kozanecki, Witold; Kozhin, Anatoly; Kramarenko, Viktor; Kramberger, Gregor; Krasnopevtsev, Dimitriy; Krasny, Mieczyslaw Witold; Krasznahorkay, Attila; Kraus, Jana; Kravchenko, Anton; Kreiss, Sven; Kretz, Moritz; Kretzschmar, Jan; Kreutzfeldt, Kristof; Krieger, Peter; Krizka, Karol; Kroeninger, Kevin; Kroha, Hubert; Kroll, Joe; Kroseberg, Juergen; Krstic, Jelena; Kruchonak, Uladzimir; Krüger, Hans; Krumnack, Nils; Kruse, Amanda; Kruse, Mark; Kruskal, Michael; Kubota, Takashi; Kucuk, Hilal; Kuday, Sinan; Kuehn, Susanne; Kugel, Andreas; Kuger, Fabian; Kuhl, Andrew; Kuhl, Thorsten; Kukhtin, Victor; Kulchitsky, Yuri; Kuleshov, Sergey; Kuna, Marine; Kunigo, Takuto; Kupco, Alexander; Kurashige, Hisaya; Kurochkin, Yurii; Kus, Vlastimil; Kuwertz, Emma Sian; Kuze, Masahiro; Kvita, Jiri; Kwan, Tony; Kyriazopoulos, Dimitrios; La Rosa, Alessandro; La Rosa Navarro, Jose Luis; La Rotonda, Laura; Lacasta, Carlos; Lacava, Francesco; Lacey, James; Lacker, Heiko; Lacour, Didier; Lacuesta, Vicente Ramón; Ladygin, Evgueni; Lafaye, Remi; Laforge, Bertrand; Lagouri, Theodota; Lai, Stanley; Lambourne, Luke; Lammers, Sabine; Lampen, Caleb; Lampl, Walter; Lançon, Eric; Landgraf, Ulrich; Landon, Murrough; Lang, Valerie Susanne; Lange, J örn Christian; Lankford, Andrew; Lanni, Francesco; Lantzsch, Kerstin; Lanza, Agostino; Laplace, Sandrine; Lapoire, Cecile; Laporte, Jean-Francois; Lari, Tommaso; Lasagni Manghi, Federico; Lassnig, Mario; Laurelli, Paolo; Lavrijsen, Wim; Law, Alexander; Laycock, Paul; Lazovich, Tomo; Le Dortz, Olivier; Le Guirriec, Emmanuel; Le Menedeu, Eve; LeBlanc, Matthew Edgar; LeCompte, Thomas; Ledroit-Guillon, Fabienne Agnes Marie; Lee, Claire Alexandra; Lee, Shih-Chang; Lee, Lawrence; Lefebvre, Guillaume; Lefebvre, Michel; Legger, Federica; Leggett, Charles; Lehan, Allan; Lehmann Miotto, Giovanna; Lei, Xiaowen; Leight, William Axel; Leisos, Antonios; Leister, Andrew Gerard; Leite, Marco Aurelio Lisboa; Leitner, Rupert; Lellouch, Daniel; Lemmer, Boris; Leney, Katharine; Lenz, Tatjana; Lenzi, Bruno; Leone, Robert; Leone, Sandra; Leonidopoulos, Christos; Leontsinis, Stefanos; Lerner, Giuseppe; Leroy, Claude; Lester, Christopher; Levchenko, Mikhail; Levêque, Jessica; Levin, Daniel; Levinson, Lorne; Levy, Mark; Lewis, Adrian; Leyko, Agnieszka; Leyton, Michael; Li, Bing; Li, Haifeng; Li, Ho Ling; Li, Lei; Li, Liang; Li, Shu; Li, Yichen; Liang, Zhijun; Liao, Hongbo; Liberti, Barbara; Liblong, Aaron; Lichard, Peter; Lie, Ki; Liebal, Jessica; Liebig, Wolfgang; Limbach, Christian; Limosani, Antonio; Lin, Simon; Lin, Tai-Hua; Linde, Frank; Lindquist, Brian Edward; Linnemann, James; Lipeles, Elliot; Lipniacka, Anna; Lisovyi, Mykhailo; Liss, Tony; Lissauer, David; Lister, Alison; Litke, Alan; Liu, Bo; Liu, Dong; Liu, Hao; Liu, Jian; Liu, Jianbei; Liu, Kun; Liu, Lulu; Liu, Miaoyuan; Liu, Minghui; Liu, Yanwen; Livan, Michele; Lleres, Annick; Llorente Merino, Javier; Lloyd, Stephen; Lo Sterzo, Francesco; Lobodzinska, Ewelina; Loch, Peter; Lockman, William; Loebinger, Fred; Loevschall-Jensen, Ask Emil; Loginov, Andrey; Lohse, Thomas; Lohwasser, Kristin; Lokajicek, Milos; Long, Brian Alexander; Long, Jonathan David; Long, Robin Eamonn; Looper, Kristina Anne; Lopes, Lourenco; Lopez Mateos, David; Lopez Paredes, Brais; Lopez Paz, Ivan; Lorenz, Jeanette; Lorenzo Martinez, Narei; Losada, Marta; Loscutoff, Peter; Lösel, Philipp Jonathan; Lou, XinChou; Lounis, Abdenour; Love, Jeremy; Love, Peter; Lu, Nan; Lubatti, Henry; Luci, Claudio; Lucotte, Arnaud; Luehring, Frederick; Lukas, Wolfgang; Luminari, Lamberto; Lundberg, Olof; Lund-Jensen, Bengt; Lynn, David; Lysak, Roman; Lytken, Else; Ma, Hong; Ma, Lian Liang; Maccarrone, Giovanni; Macchiolo, Anna; Macdonald, Calum Michael; Machado Miguens, Joana; Macina, Daniela; Madaffari, Daniele; Madar, Romain; Maddocks, Harvey Jonathan; Mader, Wolfgang; Madsen, Alexander; Maeland, Steffen; Maeno, Tadashi; Maevskiy, Artem; Magradze, Erekle; Mahboubi, Kambiz; Mahlstedt, Joern; Maiani, Camilla; Maidantchik, Carmen; Maier, Andreas Alexander; Maier, Thomas; Maio, Amélia; Majewski, Stephanie; Makida, Yasuhiro; Makovec, Nikola; Malaescu, Bogdan; Malecki, Pawel; Maleev, Victor; Malek, Fairouz; Mallik, Usha; Malon, David; Malone, Caitlin; Maltezos, Stavros; Malyshev, Vladimir; Malyukov, Sergei; Mamuzic, Judita; Mancini, Giada; Mandelli, Beatrice; Mandelli, Luciano; Mandić, Igor; Mandrysch, Rocco; Maneira, José; Manfredini, Alessandro; Manhaes de Andrade Filho, Luciano; Manjarres Ramos, Joany; Mann, Alexander; Manning, Peter; Manousakis-Katsikakis, Arkadios; Mansoulie, Bruno; Mantifel, Rodger; Mantoani, Matteo; Mapelli, Livio; March, Luis; Marchiori, Giovanni; Marcisovsky, Michal; Marino, Christopher; Marjanovic, Marija; Marley, Daniel; Marroquim, Fernando; Marsden, Stephen Philip; Marshall, Zach; Marti, Lukas Fritz; Marti-Garcia, Salvador; Martin, Brian Thomas; Martin, Tim; Martin, Victoria Jane; Martin dit Latour, Bertrand; Martinez, Mario; Martin-Haugh, Stewart; Martoiu, Victor Sorin; Martyniuk, Alex; Marx, Marilyn; Marzano, Francesco; Marzin, Antoine; Masetti, Lucia; Mashimo, Tetsuro; Mashinistov, Ruslan; Masik, Jiri; Maslennikov, Alexey; Massa, Ignazio; Massa, Lorenzo; Massol, Nicolas; Mastrandrea, Paolo; Mastroberardino, Anna; Masubuchi, Tatsuya; Mättig, Peter; Mattmann, Johannes; Maurer, Julien; Maxfield, Stephen; Maximov, Dmitriy; Mazini, Rachid; Mazza, Simone Michele; Mazzaferro, Luca; Mc Goldrick, Garrin; Mc Kee, Shawn Patrick; McCarn, Allison; McCarthy, Robert; McCarthy, Tom; McCubbin, Norman; McFarlane, Kenneth; Mcfayden, Josh; Mchedlidze, Gvantsa; McMahon, Steve; McPherson, Robert; Medinnis, Michael; Meehan, Samuel; Mehlhase, Sascha; Mehta, Andrew; Meier, Karlheinz; Meineck, Christian; Meirose, Bernhard; Mellado Garcia, Bruce Rafael; Meloni, Federico; Mengarelli, Alberto; Menke, Sven; Meoni, Evelin; Mercurio, Kevin Michael; Mergelmeyer, Sebastian; Mermod, Philippe; Merola, Leonardo; Meroni, Chiara; Merritt, Frank; Messina, Andrea; Metcalfe, Jessica; Mete, Alaettin Serhan; Meyer, Carsten; Meyer, Christopher; Meyer, Jean-Pierre; Meyer, Jochen; Middleton, Robin; Miglioranzi, Silvia; Mijović, Liza; Mikenberg, Giora; Mikestikova, Marcela; Mikuž, Marko; Milesi, Marco; Milic, Adriana; Miller, David; Mills, Corrinne; Milov, Alexander; Milstead, David; Minaenko, Andrey; Minami, Yuto; Minashvili, Irakli; Mincer, Allen; Mindur, Bartosz; Mineev, Mikhail; Ming, Yao; Mir, Lluisa-Maria; Mitani, Takashi; Mitrevski, Jovan; Mitsou, Vasiliki A; Miucci, Antonio; Miyagawa, Paul; Mjörnmark, Jan-Ulf; Moa, Torbjoern; Mochizuki, Kazuya; Mohapatra, Soumya; Mohr, Wolfgang; Molander, Simon; Moles-Valls, Regina; Mönig, Klaus; Monini, Caterina; Monk, James; Monnier, Emmanuel; Montejo Berlingen, Javier; Monticelli, Fernando; Monzani, Simone; Moore, Roger; Morange, Nicolas; Moreno, Deywis; Moreno Llácer, María; Morettini, Paolo; Morgenstern, Marcus; Mori, Daniel; Morii, Masahiro; Morinaga, Masahiro; Morisbak, Vanja; Moritz, Sebastian; Morley, Anthony Keith; Mornacchi, Giuseppe; Morris, John; Mortensen, Simon Stark; Morton, Alexander; Morvaj, Ljiljana; Mosidze, Maia; Moss, Josh; Motohashi, Kazuki; Mount, Richard; Mountricha, Eleni; Mouraviev, Sergei; Moyse, Edward; Muanza, Steve; Mudd, Richard; Mueller, Felix; Mueller, James; Mueller, Ralph Soeren Peter; Mueller, Thibaut; Muenstermann, Daniel; Mullen, Paul; Mullier, Geoffrey; Murillo Quijada, Javier Alberto; Murray, Bill; Musheghyan, Haykuhi; Musto, Elisa; Myagkov, Alexey; Myska, Miroslav; Nachman, Benjamin Philip; Nackenhorst, Olaf; Nadal, Jordi; Nagai, Koichi; Nagai, Ryo; Nagai, Yoshikazu; Nagano, Kunihiro; Nagarkar, Advait; Nagasaka, Yasushi; Nagata, Kazuki; Nagel, Martin; Nagy, Elemer; Nairz, Armin Michael; Nakahama, Yu; Nakamura, Koji; Nakamura, Tomoaki; Nakano, Itsuo; Namasivayam, Harisankar; Naranjo Garcia, Roger Felipe; Narayan, Rohin; Naumann, Thomas; Navarro, Gabriela; Nayyar, Ruchika; Neal, Homer; Nechaeva, Polina; Neep, Thomas James; Nef, Pascal Daniel; Negri, Andrea; Negrini, Matteo; Nektarijevic, Snezana; Nellist, Clara; Nelson, Andrew; Nemecek, Stanislav; Nemethy, Peter; Nepomuceno, Andre Asevedo; Nessi, Marzio; Neubauer, Mark; Neumann, Manuel; Neves, Ricardo; Nevski, Pavel; Newman, Paul; Nguyen, Duong Hai; Nickerson, Richard; Nicolaidou, Rosy; Nicquevert, Bertrand; Nielsen, Jason; Nikiforou, Nikiforos; Nikiforov, Andriy; Nikolaenko, Vladimir; Nikolic-Audit, Irena; Nikolopoulos, Konstantinos; Nilsen, Jon Kerr; Nilsson, Paul; Ninomiya, Yoichi; Nisati, Aleandro; Nisius, Richard; Nobe, Takuya; Nomachi, Masaharu; Nomidis, Ioannis; Nooney, Tamsin; Norberg, Scarlet; Nordberg, Markus; Novgorodova, Olga; Nowak, Sebastian; Nozaki, Mitsuaki; Nozka, Libor; Ntekas, Konstantinos; Nunes Hanninger, Guilherme; Nunnemann, Thomas; Nurse, Emily; Nuti, Francesco; O'Brien, Brendan Joseph; O'grady, Fionnbarr; O'Neil, Dugan; O'Shea, Val; Oakham, Gerald; Oberlack, Horst; Obermann, Theresa; Ocariz, Jose; Ochi, Atsuhiko; Ochoa, Ines; Ochoa-Ricoux, Juan Pedro; Oda, Susumu; Odaka, Shigeru; Ogren, Harold; Oh, Alexander; Oh, Seog; Ohm, Christian; Ohman, Henrik; Oide, Hideyuki; Okamura, Wataru; Okawa, Hideki; Okumura, Yasuyuki; Okuyama, Toyonobu; Olariu, Albert; Olivares Pino, Sebastian Andres; Oliveira Damazio, Denis; Oliver Garcia, Elena; Olszewski, Andrzej; Olszowska, Jolanta; Onofre, António; Onyisi, Peter; Oram, Christopher; Oreglia, Mark; Oren, Yona; Orestano, Domizia; Orlando, Nicola; Oropeza Barrera, Cristina; Orr, Robert; Osculati, Bianca; Ospanov, Rustem; Otero y Garzon, Gustavo; Otono, Hidetoshi; Ouchrif, Mohamed; Ouellette, Eric; Ould-Saada, Farid; Ouraou, Ahmimed; Oussoren, Koen Pieter; Ouyang, Qun; Ovcharova, Ana; Owen, Mark; Owen, Rhys Edward; Ozcan, Veysi Erkcan; Ozturk, Nurcan; Pachal, Katherine; Pacheco Pages, Andres; Padilla Aranda, Cristobal; Pagáčová, Martina; Pagan Griso, Simone; Paganis, Efstathios; Paige, Frank; Pais, Preema; Pajchel, Katarina; Palacino, Gabriel; Palestini, Sandro; Palka, Marek; Pallin, Dominique; Palma, Alberto; Pan, Yibin; Panagiotopoulou, Evgenia; Pandini, Carlo Enrico; Panduro Vazquez, William; Pani, Priscilla; Panitkin, Sergey; Pantea, Dan; Paolozzi, Lorenzo; Papadopoulou, Theodora; Papageorgiou, Konstantinos; Paramonov, Alexander; Paredes Hernandez, Daniela; Parker, Michael Andrew; Parker, Kerry Ann; Parodi, Fabrizio; Parsons, John; Parzefall, Ulrich; Pasqualucci, Enrico; Passaggio, Stefano; Pastore, Fernanda; Pastore, Francesca; Pásztor, Gabriella; Pataraia, Sophio; Patel, Nikhul; Pater, Joleen; Pauly, Thilo; Pearce, James; Pearson, Benjamin; Pedersen, Lars Egholm; Pedersen, Maiken; Pedraza Lopez, Sebastian; Pedro, Rute; Peleganchuk, Sergey; Pelikan, Daniel; Penc, Ondrej; Peng, Cong; Peng, Haiping; Penning, Bjoern; Penwell, John; Perepelitsa, Dennis; Perez Codina, Estel; Pérez García-Estañ, María Teresa; Perini, Laura; Pernegger, Heinz; Perrella, Sabrina; Peschke, Richard; Peshekhonov, Vladimir; Peters, Krisztian; Peters, Yvonne; Petersen, Brian; Petersen, Troels; Petit, Elisabeth; Petridis, Andreas; Petridou, Chariclia; Petroff, Pierre; Petrolo, Emilio; Petrucci, Fabrizio; Pettersson, Nora Emilia; Pezoa, Raquel; Phillips, Peter William; Piacquadio, Giacinto; Pianori, Elisabetta; Picazio, Attilio; Piccaro, Elisa; Piccinini, Maurizio; Pickering, Mark Andrew; Piegaia, Ricardo; Pignotti, David; Pilcher, James; Pilkington, Andrew; Pina, João Antonio; Pinamonti, Michele; Pinfold, James; Pingel, Almut; Pinto, Belmiro; Pires, Sylvestre; Pirumov, Hayk; Pitt, Michael; Pizio, Caterina; Plazak, Lukas; Pleier, Marc-Andre; Pleskot, Vojtech; Plotnikova, Elena; Plucinski, Pawel; Pluth, Daniel; Poettgen, Ruth; Poggioli, Luc; Pohl, David-leon; Polesello, Giacomo; Poley, Anne-luise; Policicchio, Antonio; Polifka, Richard; Polini, Alessandro; Pollard, Christopher Samuel; Polychronakos, Venetios; Pommès, Kathy; Pontecorvo, Ludovico; Pope, Bernard; Popeneciu, Gabriel Alexandru; Popovic, Dragan; Poppleton, Alan; Pospisil, Stanislav; Potamianos, Karolos; Potrap, Igor; Potter, Christina; Potter, Christopher; Poulard, Gilbert; Poveda, Joaquin; Pozdnyakov, Valery; Pralavorio, Pascal; Pranko, Aliaksandr; Prasad, Srivas; Prell, Soeren; Price, Darren; Price, Lawrence; Primavera, Margherita; Prince, Sebastien; Proissl, Manuel; Prokofiev, Kirill; Prokoshin, Fedor; Protopapadaki, Eftychia-sofia; Protopopescu, Serban; Proudfoot, James; Przybycien, Mariusz; Ptacek, Elizabeth; Puddu, Daniele; Pueschel, Elisa; Puldon, David; Purohit, Milind; Puzo, Patrick; Qian, Jianming; Qin, Gang; Qin, Yang; Quadt, Arnulf; Quarrie, David; Quayle, William; Queitsch-Maitland, Michaela; Quilty, Donnchadha; Raddum, Silje; Radeka, Veljko; Radescu, Voica; Radhakrishnan, Sooraj Krishnan; Radloff, Peter; Rados, Pere; Ragusa, Francesco; Rahal, Ghita; Rajagopalan, Srinivasan; Rammensee, Michael; Rangel-Smith, Camila; Rauscher, Felix; Rave, Stefan; Ravenscroft, Thomas; Raymond, Michel; Read, Alexander Lincoln; Readioff, Nathan Peter; Rebuzzi, Daniela; Redelbach, Andreas; Redlinger, George; Reece, Ryan; Reeves, Kendall; Rehnisch, Laura; Reichert, Joseph; Reisin, Hernan; Relich, Matthew; Rembser, Christoph; Ren, Huan; Renaud, Adrien; Rescigno, Marco; Resconi, Silvia; Rezanova, Olga; Reznicek, Pavel; Rezvani, Reyhaneh; Richter, Robert; Richter, Stefan; Richter-Was, Elzbieta; Ricken, Oliver; Ridel, Melissa; Rieck, Patrick; Riegel, Christian Johann; Rieger, Julia; Rijssenbeek, Michael; Rimoldi, Adele; Rinaldi, Lorenzo; Ristić, Branislav; Ritsch, Elmar; Riu, Imma; Rizatdinova, Flera; Rizvi, Eram; Robertson, Steven; Robichaud-Veronneau, Andree; Robinson, Dave; Robinson, James; Robson, Aidan; Roda, Chiara; Roe, Shaun; Røhne, Ole; Rolli, Simona; Romaniouk, Anatoli; Romano, Marino; Romano Saez, Silvestre Marino; Romero Adam, Elena; Rompotis, Nikolaos; Ronzani, Manfredi; Roos, Lydia; Ros, Eduardo; Rosati, Stefano; Rosbach, Kilian; Rose, Peyton; Rosendahl, Peter Lundgaard; Rosenthal, Oliver; Rossetti, Valerio; Rossi, Elvira; Rossi, Leonardo Paolo; Rosten, Rachel; Rotaru, Marina; Roth, Itamar; Rothberg, Joseph; Rousseau, David; Royon, Christophe; Rozanov, Alexandre; Rozen, Yoram; Ruan, Xifeng; Rubbo, Francesco; Rubinskiy, Igor; Rud, Viacheslav; Rudolph, Christian; Rudolph, Matthew Scott; Rühr, Frederik; Ruiz-Martinez, Aranzazu; Rurikova, Zuzana; Rusakovich, Nikolai; Ruschke, Alexander; Russell, Heather; Rutherfoord, John; Ruthmann, Nils; Ryabov, Yury; Rybar, Martin; Rybkin, Grigori; Ryder, Nick; Saavedra, Aldo; Sabato, Gabriele; Sacerdoti, Sabrina; Saddique, Asif; Sadrozinski, Hartmut; Sadykov, Renat; Safai Tehrani, Francesco; Saimpert, Matthias; Saito, Tomoyuki; Sakamoto, Hiroshi; Sakurai, Yuki; Salamanna, Giuseppe; Salamon, Andrea; Saleem, Muhammad; Salek, David; Sales De Bruin, Pedro Henrique; Salihagic, Denis; Salnikov, Andrei; Salt, José; Salvatore, Daniela; Salvatore, Pasquale Fabrizio; Salvucci, Antonio; Salzburger, Andreas; Sammel, Dirk; Sampsonidis, Dimitrios; Sanchez, Arturo; Sánchez, Javier; Sanchez Martinez, Victoria; Sandaker, Heidi; Sandbach, Ruth Laura; Sander, Heinz Georg; Sanders, Michiel; Sandhoff, Marisa; Sandoval, Carlos; Sandstroem, Rikard; Sankey, Dave; Sannino, Mario; Sansoni, Andrea; Santoni, Claudio; Santonico, Rinaldo; Santos, Helena; Santoyo Castillo, Itzebelt; Sapp, Kevin; Sapronov, Andrey; Saraiva, João; Sarrazin, Bjorn; Sasaki, Osamu; Sasaki, Yuichi; Sato, Koji; Sauvage, Gilles; Sauvan, Emmanuel; Savage, Graham; Savard, Pierre; Sawyer, Craig; Sawyer, Lee; Saxon, James; Sbarra, Carla; Sbrizzi, Antonio; Scanlon, Tim; Scannicchio, Diana; Scarcella, Mark; Scarfone, Valerio; Schaarschmidt, Jana; Schacht, Peter; Schaefer, Douglas; Schaefer, Ralph; Schaeffer, Jan; Schaepe, Steffen; Schaetzel, Sebastian; Schäfer, Uli; Schaffer, Arthur; Schaile, Dorothee; Schamberger, R Dean; Scharf, Veit; Schegelsky, Valery; Scheirich, Daniel; Schernau, Michael; Schiavi, Carlo; Schillo, Christian; Schioppa, Marco; Schlenker, Stefan; Schmidt, Evelyn; Schmieden, Kristof; Schmitt, Christian; Schmitt, Sebastian; Schmitt, Stefan; Schneider, Basil; Schnellbach, Yan Jie; Schnoor, Ulrike; Schoeffel, Laurent; Schoening, Andre; Schoenrock, Bradley Daniel; Schopf, Elisabeth; Schorlemmer, Andre Lukas; Schott, Matthias; Schouten, Doug; Schovancova, Jaroslava; Schramm, Steven; Schreyer, Manuel; Schroeder, Christian; Schuh, Natascha; Schultens, Martin Johannes; Schultz-Coulon, Hans-Christian; Schulz, Holger; Schumacher, Markus; Schumm, Bruce; Schune, Philippe; Schwanenberger, Christian; Schwartzman, Ariel; Schwarz, Thomas Andrew; Schwegler, Philipp; Schweiger, Hansdieter; Schwemling, Philippe; Schwienhorst, Reinhard; Schwindling, Jerome; Schwindt, Thomas; Sciacca, Gianfranco; Scifo, Estelle; Sciolla, Gabriella; Scuri, Fabrizio; Scutti, Federico; Searcy, Jacob; Sedov, George; Sedykh, Evgeny; Seema, Pienpen; Seidel, Sally; Seiden, Abraham; Seifert, Frank; Seixas, José; Sekhniaidze, Givi; Sekhon, Karishma; Sekula, Stephen; Seliverstov, Dmitry; Semprini-Cesari, Nicola; Serfon, Cedric; Serin, Laurent; Serkin, Leonid; Serre, Thomas; Sessa, Marco; Seuster, Rolf; Severini, Horst; Sfiligoj, Tina; Sforza, Federico; Sfyrla, Anna; Shabalina, Elizaveta; Shamim, Mansoora; Shan, Lianyou; Shang, Ruo-yu; Shank, James; Shapiro, Marjorie; Shatalov, Pavel; Shaw, Kate; Shaw, Savanna Marie; Shcherbakova, Anna; Shehu, Ciwake Yusufu; Sherwood, Peter; Shi, Liaoshan; Shimizu, Shima; Shimmin, Chase Owen; Shimojima, Makoto; Shiyakova, Mariya; Shmeleva, Alevtina; Shoaleh Saadi, Diane; Shochet, Mel; Shojaii, Seyedruhollah; Shrestha, Suyog; Shulga, Evgeny; Shupe, Michael; Shushkevich, Stanislav; Sicho, Petr; Sidebo, Per Edvin; Sidiropoulou, Ourania; Sidorov, Dmitri; Sidoti, Antonio; Siegert, Frank; Sijacki, Djordje; Silva, José; Silver, Yiftah; Silverstein, Samuel; Simak, Vladislav; Simard, Olivier; Simic, Ljiljana; Simion, Stefan; Simioni, Eduard; Simmons, Brinick; Simon, Dorian; Simoniello, Rosa; Sinervo, Pekka; Sinev, Nikolai; Sioli, Maximiliano; Siragusa, Giovanni; Sisakyan, Alexei; Sivoklokov, Serguei; Sjölin, Jörgen; Sjursen, Therese; Skinner, Malcolm Bruce; Skottowe, Hugh Philip; Skubic, Patrick; Slater, Mark; Slavicek, Tomas; Slawinska, Magdalena; Sliwa, Krzysztof; Smakhtin, Vladimir; Smart, Ben; Smestad, Lillian; Smirnov, Sergei; Smirnov, Yury; Smirnova, Lidia; Smirnova, Oxana; Smith, Matthew; Smith, Russell; Smizanska, Maria; Smolek, Karel; Snesarev, Andrei; Snidero, Giacomo; Snyder, Scott; Sobie, Randall; Socher, Felix; Soffer, Abner; Soh, Dart-yin; Solans, Carlos; Solar, Michael; Solc, Jaroslav; Soldatov, Evgeny; Soldevila, Urmila; Solodkov, Alexander; Soloshenko, Alexei; Solovyanov, Oleg; Solovyev, Victor; Sommer, Philip; Song, Hong Ye; Soni, Nitesh; Sood, Alexander; Sopczak, Andre; Sopko, Bruno; Sopko, Vit; Sorin, Veronica; Sosa, David; Sosebee, Mark; Sotiropoulou, Calliope Louisa; Soualah, Rachik; Soukharev, Andrey; South, David; Sowden, Benjamin; Spagnolo, Stefania; Spalla, Margherita; Spanò, Francesco; Spearman, William Robert; Sperlich, Dennis; Spettel, Fabian; Spighi, Roberto; Spigo, Giancarlo; Spiller, Laurence Anthony; Spousta, Martin; Spreitzer, Teresa; St Denis, Richard Dante; Staerz, Steffen; Stahlman, Jonathan; Stamen, Rainer; Stamm, Soren; Stanecka, Ewa; Stanescu, Cristian; Stanescu-Bellu, Madalina; Stanitzki, Marcel Michael; Stapnes, Steinar; Starchenko, Evgeny; Stark, Jan; Staroba, Pavel; Starovoitov, Pavel; Staszewski, Rafal; Stavina, Pavel; Steinberg, Peter; Stelzer, Bernd; Stelzer, Harald Joerg; Stelzer-Chilton, Oliver; Stenzel, Hasko; Stewart, Graeme; Stillings, Jan Andre; Stockton, Mark; Stoebe, Michael; Stoicea, Gabriel; Stolte, Philipp; Stonjek, Stefan; Stradling, Alden; Straessner, Arno; Stramaglia, Maria Elena; Strandberg, Jonas; Strandberg, Sara; Strandlie, Are; Strauss, Emanuel; Strauss, Michael; Strizenec, Pavol; Ströhmer, Raimund; Strom, David; Stroynowski, Ryszard; Strubig, Antonia; Stucci, Stefania Antonia; Stugu, Bjarne; Styles, Nicholas Adam; Su, Dong; Su, Jun; Subramaniam, Rajivalochan; Succurro, Antonella; Sugaya, Yorihito; Suhr, Chad; Suk, Michal; Sulin, Vladimir; Sultansoy, Saleh; Sumida, Toshi; Sun, Siyuan; Sun, Xiaohu; Sundermann, Jan Erik; Suruliz, Kerim; Susinno, Giancarlo; Sutton, Mark; Suzuki, Shota; Svatos, Michal; Swedish, Stephen; Swiatlowski, Maximilian; Sykora, Ivan; Sykora, Tomas; Ta, Duc; Taccini, Cecilia; Tackmann, Kerstin; Taenzer, Joe; Taffard, Anyes; Tafirout, Reda; Taiblum, Nimrod; Takai, Helio; Takashima, Ryuichi; Takeda, Hiroshi; Takeshita, Tohru; Takubo, Yosuke; Talby, Mossadek; Talyshev, Alexey; Tam, Jason; Tan, Kong Guan; Tanaka, Junichi; Tanaka, Reisaburo; Tanaka, Shuji; Tannenwald, Benjamin Bordy; Tannoury, Nancy; Tapprogge, Stefan; Tarem, Shlomit; Tarrade, Fabien; Tartarelli, Giuseppe Francesco; Tas, Petr; Tasevsky, Marek; Tashiro, Takuya; Tassi, Enrico; Tavares Delgado, Ademar; Tayalati, Yahya; Taylor, Frank; Taylor, Geoffrey; Taylor, Wendy; Teischinger, Florian Alfred; Teixeira Dias Castanheira, Matilde; Teixeira-Dias, Pedro; Temming, Kim Katrin; Ten Kate, Herman; Teng, Ping-Kun; Teoh, Jia Jian; Tepel, Fabian-Phillipp; Terada, Susumu; Terashi, Koji; Terron, Juan; Terzo, Stefano; Testa, Marianna; Teuscher, Richard; Theveneaux-Pelzer, Timothée; Thomas, Juergen; Thomas-Wilsker, Joshuha; Thompson, Emily; Thompson, Paul; Thompson, Ray; Thompson, Stan; Thomsen, Lotte Ansgaard; Thomson, Evelyn; Thomson, Mark; Thun, Rudolf; Tibbetts, Mark James; Ticse Torres, Royer Edson; Tikhomirov, Vladimir; Tikhonov, Yury; Timoshenko, Sergey; Tiouchichine, Elodie; Tipton, Paul; Tisserant, Sylvain; Todome, Kazuki; Todorov, Theodore; Todorova-Nova, Sharka; Tojo, Junji; Tokár, Stanislav; Tokushuku, Katsuo; Tollefson, Kirsten; Tolley, Emma; Tomlinson, Lee; Tomoto, Makoto; Tompkins, Lauren; Toms, Konstantin; Torrence, Eric; Torres, Heberth; Torró Pastor, Emma; Toth, Jozsef; Touchard, Francois; Tovey, Daniel; Trefzger, Thomas; Tremblet, Louis; Tricoli, Alessandro; Trigger, Isabel Marian; Trincaz-Duvoid, Sophie; Tripiana, Martin; Trischuk, William; Trocmé, Benjamin; Troncon, Clara; Trottier-McDonald, Michel; Trovatelli, Monica; True, Patrick; Truong, Loan; Trzebinski, Maciej; Trzupek, Adam; Tsarouchas, Charilaos; Tseng, Jeffrey; Tsiareshka, Pavel; Tsionou, Dimitra; Tsipolitis, Georgios; Tsirintanis, Nikolaos; Tsiskaridze, Shota; Tsiskaridze, Vakhtang; Tskhadadze, Edisher; Tsukerman, Ilya; Tsulaia, Vakhtang; Tsuno, Soshi; Tsybychev, Dmitri; Tudorache, Alexandra; Tudorache, Valentina; Tuna, Alexander Naip; Tupputi, Salvatore; Turchikhin, Semen; Turecek, Daniel; Turra, Ruggero; Turvey, Andrew John; Tuts, Michael; Tykhonov, Andrii; Tylmad, Maja; Tyndel, Mike; Ueda, Ikuo; Ueno, Ryuichi; Ughetto, Michael; Ugland, Maren; Uhlenbrock, Mathias; Ukegawa, Fumihiko; Unal, Guillaume; Undrus, Alexander; Unel, Gokhan; Ungaro, Francesca; Unno, Yoshinobu; Unverdorben, Christopher; Urban, Jozef; Urquijo, Phillip; Urrejola, Pedro; Usai, Giulio; Usanova, Anna; Vacavant, Laurent; Vacek, Vaclav; Vachon, Brigitte; Valderanis, Chrysostomos; Valencic, Nika; Valentinetti, Sara; Valero, Alberto; Valery, Loic; Valkar, Stefan; Valladolid Gallego, Eva; Vallecorsa, Sofia; Valls Ferrer, Juan Antonio; Van Den Wollenberg, Wouter; Van Der Deijl, Pieter; van der Geer, Rogier; van der Graaf, Harry; Van Der Leeuw, Robin; van Eldik, Niels; van Gemmeren, Peter; Van Nieuwkoop, Jacobus; van Vulpen, Ivo; van Woerden, Marius Cornelis; Vanadia, Marco; Vandelli, Wainer; Vanguri, Rami; Vaniachine, Alexandre; Vannucci, Francois; Vardanyan, Gagik; Vari, Riccardo; Varnes, Erich; Varol, Tulin; Varouchas, Dimitris; Vartapetian, Armen; Varvell, Kevin; Vazeille, Francois; Vazquez Schroeder, Tamara; Veatch, Jason; Veloce, Laurelle Maria; Veloso, Filipe; Velz, Thomas; Veneziano, Stefano; Ventura, Andrea; Ventura, Daniel; Venturi, Manuela; Venturi, Nicola; Venturini, Alessio; Vercesi, Valerio; Verducci, Monica; Verkerke, Wouter; Vermeulen, Jos; Vest, Anja; Vetterli, Michel; Viazlo, Oleksandr; Vichou, Irene; Vickey, Trevor; Vickey Boeriu, Oana Elena; Viehhauser, Georg; Viel, Simon; Vigne, Ralph; Villa, Mauro; Villaplana Perez, Miguel; Vilucchi, Elisabetta; Vincter, Manuella; Vinogradov, Vladimir; Vivarelli, Iacopo; Vives Vaque, Francesc; Vlachos, Sotirios; Vladoiu, Dan; Vlasak, Michal; Vogel, Marcelo; Vokac, Petr; Volpi, Guido; Volpi, Matteo; von der Schmitt, Hans; von Radziewski, Holger; von Toerne, Eckhard; Vorobel, Vit; Vorobev, Konstantin; Vos, Marcel; Voss, Rudiger; Vossebeld, Joost; Vranjes, Nenad; Vranjes Milosavljevic, Marija; Vrba, Vaclav; Vreeswijk, Marcel; Vuillermet, Raphael; Vukotic, Ilija; Vykydal, Zdenek; Wagner, Peter; Wagner, Wolfgang; Wahlberg, Hernan; Wahrmund, Sebastian; Wakabayashi, Jun; Walder, James; Walker, Rodney; Walkowiak, Wolfgang; Wang, Chao; Wang, Fuquan; Wang, Haichen; Wang, Hulin; Wang, Jike; Wang, Jin; Wang, Kuhan; Wang, Rui; Wang, Song-Ming; Wang, Tan; Wang, Tingting; Wang, Xiaoxiao; Wanotayaroj, Chaowaroj; Warburton, Andreas; Ward, Patricia; Wardrope, David Robert; Warsinsky, Markus; Washbrook, Andrew; Wasicki, Christoph; Watkins, Peter; Watson, Alan; Watson, Ian; Watson, Miriam; Watts, Gordon; Watts, Stephen; Waugh, Ben; Webb, Samuel; Weber, Michele; Weber, Stefan Wolf; Webster, Jordan S; Weidberg, Anthony; Weinert, Benjamin; Weingarten, Jens; Weiser, Christian; Weits, Hartger; Wells, Phillippa; Wenaus, Torre; Wengler, Thorsten; Wenig, Siegfried; Wermes, Norbert; Werner, Matthias; Werner, Per; Wessels, Martin; Wetter, Jeffrey; Whalen, Kathleen; Wharton, Andrew Mark; White, Andrew; White, Martin; White, Ryan; White, Sebastian; Whiteson, Daniel; Wickens, Fred; Wiedenmann, Werner; Wielers, Monika; Wienemann, Peter; Wiglesworth, Craig; Wiik-Fuchs, Liv Antje Mari; Wildauer, Andreas; Wilkens, Henric George; Williams, Hugh; Williams, Sarah; Willis, Christopher; Willocq, Stephane; Wilson, Alan; Wilson, John; Wingerter-Seez, Isabelle; Winklmeier, Frank; Winter, Benedict Tobias; Wittgen, Matthias; Wittkowski, Josephine; Wollstadt, Simon Jakob; Wolter, Marcin Wladyslaw; Wolters, Helmut; Wosiek, Barbara; Wotschack, Jorg; Woudstra, Martin; Wozniak, Krzysztof; Wu, Mengqing; Wu, Miles; Wu, Sau Lan; Wu, Xin; Wu, Yusheng; Wyatt, Terry Richard; Wynne, Benjamin; Xella, Stefania; Xu, Da; Xu, Lailin; Yabsley, Bruce; Yacoob, Sahal; Yakabe, Ryota; Yamada, Miho; Yamaguchi, Yohei; Yamamoto, Akira; Yamamoto, Shimpei; Yamanaka, Takashi; Yamauchi, Katsuya; Yamazaki, Yuji; Yan, Zhen; Yang, Haijun; Yang, Hongtao; Yang, Yi; Yao, Weiming; Yasu, Yoshiji; Yatsenko, Elena; Yau Wong, Kaven Henry; Ye, Jingbo; Ye, Shuwei; Yeletskikh, Ivan; Yen, Andy L; Yildirim, Eda; Yorita, Kohei; Yoshida, Rikutaro; Yoshihara, Keisuke; Young, Charles; Young, Christopher John; Youssef, Saul; Yu, David Ren-Hwa; Yu, Jaehoon; Yu, Jiaming; Yu, Jie; Yuan, Li; Yuen, Stephanie P; Yurkewicz, Adam; Yusuff, Imran; Zabinski, Bartlomiej; Zaidan, Remi; Zaitsev, Alexander; Zalieckas, Justas; Zaman, Aungshuman; Zambito, Stefano; Zanello, Lucia; Zanzi, Daniele; Zeitnitz, Christian; Zeman, Martin; Zemla, Andrzej; Zengel, Keith; Zenin, Oleg; Ženiš, Tibor; Zerwas, Dirk; Zhang, Dongliang; Zhang, Fangzhou; Zhang, Huijun; Zhang, Jinlong; Zhang, Lei; Zhang, Ruiqi; Zhang, Xueyao; Zhang, Zhiqing; Zhao, Xiandong; Zhao, Yongke; Zhao, Zhengguo; Zhemchugov, Alexey; Zhong, Jiahang; Zhou, Bing; Zhou, Chen; Zhou, Lei; Zhou, Li; Zhou, Ning; Zhu, Cheng Guang; Zhu, Hongbo; Zhu, Junjie; Zhu, Yingchun; Zhuang, Xuai; Zhukov, Konstantin; Zibell, Andre; Zieminska, Daria; Zimine, Nikolai; Zimmermann, Christoph; Zimmermann, Stephanie; Zinonos, Zinonas; Zinser, Markus; Ziolkowski, Michael; Živković, Lidija; Zobernig, Georg; Zoccoli, Antonio; zur Nedden, Martin; Zurzolo, Giovanni; Zwalinski, Lukasz

    2015-10-29

    This paper reviews and extends searches for the direct pair production of the scalar supersymmetric partners of the top and bottom quarks in proton--proton collisions collected by the ATLAS collaboration during the LHC Run 1. Most of the analyses use 20 fb$^{-1}$ of collisions at a centre-of-mass energy of $\\sqrt{s} = 8$ TeV, although in some case an additional 4.7 fb$^{-1}$ of collision data at $\\sqrt{s}= 7$ TeV are used. New analyses are introduced to improve the sensitivity to specific regions of the model parameter space. Since no evidence of third-generation squarks is found, exclusion limits are derived by combining several analyses and are presented in both a simplified model framework, assuming simple decay chains, as well as within the context of more elaborate phenomenological supersymmetric models.

  13. Geological Evidences for a Large Tsunami Generated by the 7.3 ka Kikai Caldera Eruption, Southern Japan

    Science.gov (United States)

    Yamada, M.; Fujino, S.; Satake, K.

    2017-12-01

    The 7.3 ka eruption of Kikai volcano, southern Kyushu, Japan, is one of the largest caldera-forming eruption in the world. Given that a huge caldera was formed in shallow sea area during the eruption, a tsunami must have been generated by a sea-level change associated. Pyroclastic flow and tsunami deposits by the eruption have been studied around the caldera, but they are not enough to evaluate the tsunami size. The goal of this study is to unravel sizes of tsunami and triggering caldera collapse by numerical simulations based on a widely-distributed tsunami deposit associated with the eruption. In this presentation, we will provide an initial data on distribution of the 7.3 ka tsunami deposit contained in sediment cores taken at three coastal lowlands in Wakayama, Tokushima, and Oita prefectures (560 km, 520 km, and 310 km north-east from the caldera, respectively). A volcanic ash from the eruption (Kikai Akahoya tephra: K-Ah) is evident in organic-rich muddy sedimentary sequence in all sediment cores. Up to 6-cm-thick sand layer, characterized by a grading structure and sharp bed boundary with lower mud, is observed immediately beneath the K-Ah tephra in all study sites. These sedimentary characteristics and broad distribution indicate that the sand layer was most likely deposited by a tsunami which can propagate to a wide area, but not by a local storm surge. Furthermore, the stratigraphic relationship implies that the study sites must have been inundated by the tsunami prior to the ash fall. A sand layer is also evident within the K-Ah tephra layer, suggesting that the sand layer was probably formed by a subsequent tsunami wave during the ash fall. These geological evidences for the 7.3 ka tsunami inundation will contribute to a better understanding of the caldera collapse and the resultant tsunami, but also of the tsunami generating system in the eruptive process.

  14. Large-scale integration of renewable and distributed generation of electricity in Spain: Current situation and future needs

    International Nuclear Information System (INIS)

    Cossent, Rafael; Gómez, Tomás; Olmos, Luis

    2011-01-01

    Similar to other European countries, mechanisms for the promotion of electricity generation from renewable energy sources (RESs) and combined heat and power (CHP) production have caused a significant growth in distributed generation (DG) in Spain. Low DG/RES penetration levels do not have a major impact on electricity systems. However, several problems arise as DG shares increase. Smarter distribution grids are deemed necessary to facilitate DG/RES integration. This involves modifying the way distribution networks are currently planned and operated. Furthermore, DG and demand should also adopt a more active role. This paper reviews the current situation of DG/RES in Spain including penetration rates, support payments for DG/RES, level of market integration, economic regulation of Distribution System Operators (DSOs), smart metering implementation, grid operation and planning, and incentives for DSO innovation. This paper identifies several improvements that could be made to the treatment of DG/RES. Key aspects of an efficient DG/RES integration are identified and several regulatory changes specific to the Spanish situation are recommended. - Highlights: ► Substantial DG/RES penetration levels are foreseen for the coming years in Spain. ► Integrating such amount of DG/RES in electricity markets and networks is challenging. ► We review key regulatory aspects that may affect DG/RES integration in Spain. ► Several recommendations aimed at easing DG/RES integration in Spain are provided. ► Market integration and the transition towards smarter grids are deemed key issues.

  15. Laboratory Spectroscopy of Large Carbon Molecules and Ions in Support of Space Missions. A New Generation of Laboratory & Space Studies

    Science.gov (United States)

    Salama, Farid; Tan, Xiaofeng; Cami, Jan; Biennier, Ludovic; Remy, Jerome

    2006-01-01

    Polycyclic Aromatic Hydrocarbons (PAHs) are an important and ubiquitous component of carbon-bearing materials in space. A long-standing and major challenge for laboratory astrophysics has been to measure the spectra of large carbon molecules in laboratory environments that mimic (in a realistic way) the physical conditions that are associated with the interstellar emission and absorption regions [1]. This objective has been identified as one of the critical Laboratory Astrophysics objectives to optimize the data return from space missions [2]. An extensive laboratory program has been developed to assess the properties of PAHs in such environments and to describe how they influence the radiation and energy balance in space. We present and discuss the gas-phase electronic absorption spectra of neutral and ionized PAHs measured in the UV-Visible-NIR range in astrophysically relevant environments and discuss the implications for astrophysics [1]. The harsh physical conditions of the interstellar medium characterized by a low temperature, an absence of collisions and strong VUV radiation fields - have been simulated in the laboratory by associating a pulsed cavity ringdown spectrometer (CRDS) with a supersonic slit jet seeded with PAHs and an ionizing, penning-type, electronic discharge. We have measured for the {\\it first time} the spectra of a series of neutral [3,4] and ionized [5,6] interstellar PAHs analogs in the laboratory. An effort has also been attempted to quantify the mechanisms of ion and carbon nanoparticles production in the free jet expansion and to model our simulation of the diffuse interstellar medium in the laboratory [7]. These experiments provide {\\it unique} information on the spectra of free, large carbon-containing molecules and ions in the gas phase. We are now, for the first time, in the position to directly compare laboratory spectral data on free, cold, PAH ions and carbon nano-sized carbon particles with astronomical observations in the

  16. Analytical methods for large-scale sensitivity analysis using GRESS [GRadient Enhanced Software System] and ADGEN [Automated Adjoint Generator

    International Nuclear Information System (INIS)

    Pin, F.G.

    1988-04-01

    Sensitivity analysis is an established methodology used by researchers in almost every field to gain essential insight in design and modeling studies and in performance assessments of complex systems. Conventional sensitivity analysis methodologies, however, have not enjoyed the widespread use they deserve considering the wealth of information they can provide, partly because of their prohibitive cost or the large initial analytical investment they require. Automated systems have recently been developed at ORNL to eliminate these drawbacks. Compilers such as GRESS and ADGEN now allow automatic and cost effective calculation of sensitivities in FORTRAN computer codes. In this paper, these and other related tools are described and their impact and applicability in the general areas of modeling, performance assessment and decision making for radioactive waste isolation problems are discussed. 7 refs., 2 figs

  17. Next generation sensing platforms for extended deployments in large-scale, multidisciplinary, adaptive sampling and observational networks

    Science.gov (United States)

    Cross, J. N.; Meinig, C.; Mordy, C. W.; Lawrence-Slavas, N.; Cokelet, E. D.; Jenkins, R.; Tabisola, H. M.; Stabeno, P. J.

    2016-12-01

    New autonomous sensors have dramatically increased the resolution and accuracy of oceanographic data collection, enabling rapid sampling over extremely fine scales. Innovative new autonomous platofrms like floats, gliders, drones, and crawling moorings leverage the full potential of these new sensors by extending spatiotemporal reach across varied environments. During 2015 and 2016, The Innovative Technology for Arctic Exploration Program at the Pacific Marine Environmental Laboratory tested several new types of fully autonomous platforms with increased speed, durability, and power and payload capacity designed to deliver cutting-edge ecosystem assessment sensors to remote or inaccessible environments. The Expendable Ice-Tracking (EXIT) gloat developed by the NOAA Pacific Marine Environmental Laboratory (PMEL) is moored near bottom during the ice-free season and released on an autonomous timer beneath the ice during the following winter. The float collects a rapid profile during ascent, and continues to collect critical, poorly-accessible under-ice data until melt, when data is transmitted via satellite. The autonomous Oculus sub-surface glider developed by the University of Washington and PMEL has a large power and payload capacity and an enhanced buoyancy engine. This 'coastal truck' is designed for the rapid water column ascent required by optical imaging systems. The Saildrone is a solar and wind powered ocean unmanned surface vessel (USV) developed by Saildrone, Inc. in partnership with PMEL. This large-payload (200 lbs), fast (1-7 kts), durable (46 kts winds) platform was equipped with 15 sensors designed for ecosystem assessment during 2016, including passive and active acoustic systems specially redesigned for autonomous vehicle deployments. The senors deployed on these platforms achieved rigorous accuracy and precision standards. These innovative platforms provide new sampling capabilities and cost efficiencies in high-resolution sensor deployment

  18. Next-Generation Sequencing of the Chrysanthemum nankingense (Asteraceae) Transcriptome Permits Large-Scale Unigene Assembly and SSR Marker Discovery

    Science.gov (United States)

    Wang, Haibin; Jiang, Jiafu; Chen, Sumei; Qi, Xiangyu; Peng, Hui; Li, Pirui; Song, Aiping; Guan, Zhiyong; Fang, Weimin; Liao, Yuan; Chen, Fadi

    2013-01-01

    Background Simple sequence repeats (SSRs) are ubiquitous in eukaryotic genomes. Chrysanthemum is one of the largest genera in the Asteraceae family. Only few Chrysanthemum expressed sequence tag (EST) sequences have been acquired to date, so the number of available EST-SSR markers is very low. Methodology/Principal Findings Illumina paired-end sequencing technology produced over 53 million sequencing reads from C. nankingense mRNA. The subsequent de novo assembly yielded 70,895 unigenes, of which 45,789 (64.59%) unigenes showed similarity to the sequences in NCBI database. Out of 45,789 sequences, 107 have hits to the Chrysanthemum Nr protein database; 679 and 277 sequences have hits to the database of Helianthus and Lactuca species, respectively. MISA software identified a large number of putative EST-SSRs, allowing 1,788 primer pairs to be designed from the de novo transcriptome sequence and a further 363 from archival EST sequence. Among 100 primer pairs randomly chosen, 81 markers have amplicons and 20 are polymorphic for genotypes analysis in Chrysanthemum. The results showed that most (but not all) of the assays were transferable across species and that they exposed a significant amount of allelic diversity. Conclusions/Significance SSR markers acquired by transcriptome sequencing are potentially useful for marker-assisted breeding and genetic analysis in the genus Chrysanthemum and its related genera. PMID:23626799

  19. Large-eddy simulation of convective boundary layer generated by highly heated source with open source code, OpenFOAM

    International Nuclear Information System (INIS)

    Hattori, Yasuo; Suto, Hitoshi; Eguchi, Yuzuru; Sano, Tadashi; Shirai, Koji; Ishihara, Shuji

    2011-01-01

    Spatial- and temporal-characteristics of turbulence structures in the close vicinity of a heat source, which is a horizontal upward-facing round plate heated at high temperature, are examined by using well resolved large-eddy simulations. The verification is carried out through the comparison with experiments: the predicted statistics, including the PDF distribution of temperature fluctuations, agree well with measurements, indicating that the present simulations have a capability to appropriately reproduce turbulence structures near the heat source. The reproduced three-dimensional thermal- and fluid-fields in the close vicinity of the heat source reveals developing processes of coherence structures along the surface: the stationary- and streaky-flow patterns appear near the edge, and such patterns randomly shift to cell-like patterns with incursion into the center region, resulting in thermal-plume meandering. Both the patterns have very thin structures, but the depth of streaky structure is considerably small compared with that of cell-like patterns; this discrepancy causes the layered structures. The structure is the source of peculiar turbulence characteristics, the prediction of which is quite difficult with RANS-type turbulence models. The understanding such structures obtained in present study must be helpful to improve the turbulence model used in nuclear engineering. (author)

  20. Comprehensive molecular diagnosis of a large cohort of Japanese retinitis pigmentosa and Usher syndrome patients by next-generation sequencing.

    Science.gov (United States)

    Oishi, Maho; Oishi, Akio; Gotoh, Norimoto; Ogino, Ken; Higasa, Koichiro; Iida, Kei; Makiyama, Yukiko; Morooka, Satoshi; Matsuda, Fumihiko; Yoshimura, Nagahisa

    2014-10-16

    Retinitis pigmentosa (RP), a major cause of blindness in developed countries, has multiple causative genes; its prevalence differs by ethnicity. Usher syndrome is the most common form of syndromic RP and is accompanied by hearing impairment. Although molecular diagnosis is challenging, recent technological advances such as targeted high-throughput resequencing are efficient screening tools. We performed comprehensive molecular testing in 329 Japanese RP and Usher syndrome patients by using a custom capture panel that covered the coding exons and exon/intron boundaries of all 193 known inherited eye disease genes combined with Illumina HiSequation 2500. Candidate variants were screened using systematic data analyses, and their potential pathogenicity was assessed according to the frequency of the variants in normal populations, in silico prediction tools, and compatibility with known phenotypes or inheritance patterns. Molecular diagnoses were made in 115/317 RP patients (36.3%) and 6/12 Usher syndrome patients (50%). We identified 104 distinct mutations, including 66 novel mutations. EYS, USH2A, and RHO were common causative genes. In particular, mutations in EYS accounted for 15.0% of the autosomal recessive/simplex RP patients or 10.7% of the entire RP cohort. Among the 189 previously reported mutations detected in the current study, 55 (29.1%) were found commonly in Japanese or other public databases and were excluded from molecular diagnoses. By screening a large cohort of patients, this study catalogued the genetic variations involved in RP and Usher syndrome in a Japanese population and highlighted the different distribution of causative genes among populations. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

  1. An evaluation of effects of large-scale introduction of renewable power on capacities and operation modes of power generation systems in Japan

    International Nuclear Information System (INIS)

    Yamamoto, Hiromi; Yabe, Kuniaki; Bando, Shigeru; Nagai, Yu

    2014-01-01

    This study aims to establish a methodology to adequately evaluate an optimal power generation mix in Japan taking into account load frequency control (LFC) capacity and operation modes of power plants in case of a large-scale introduction of photovoltaic and wind power. For this purpose, the authors gave such an improvement to the MM-OPG model, a power generation mix optimization model, which it can deal with different operation modes of pumped hydro power in addition to those of thermal power sources. Using the model, the authors calculated the optimal power generation mix and its corresponding operation modes of Japan's power systems in 2030 with additional insights to 2020, and obtained the following results. (1) Introduction of photovoltaic and wind can be substituted for a limited capacity of conventional power sources. The introduction of 150 GW that consists of 108GW of photovoltaic and 42GW of wind in 2030 can replace no greater than 0.5 GW of conventional power sources. (2) The introduction of the renewables will affect the operation patterns of thermal and pumped hydro power generation. The capacity factor of variable speed pumped hydro will be much greater than that of fixed speed pumped hydro since the former can supply LFC at pump modes as well as generation modes. The capacity factor of LNG combined cycle plants decreases from 43% to 29% in the case with the introduction of 150GW of renewables in 2030. On the same assumption, the average cost of power generation excluding the renewables increases by up to 0.55 JPY/kWh in 2030. (author)

  2. Large-scale experimental facility for emergency condition investigation of a new generation NPP WWER-640 reactor with passive safety systems

    International Nuclear Information System (INIS)

    Aniskevich, Y.N.; Vasilenko, V.A.; Zasukha, V.K.; Migrov, Y.A.; Khabensky, V.B.

    1997-01-01

    The creation of the large-scale integral experimental facility (KMS) is specified by the programme of the experimental investigations to justify the engineering decisions on the safety of the design of the new generation NPP with the reactor WWER-640. The construction of KMS in a full volume will allow to conduct experimental investigations of all physical phenomena and processes, practically, occurring during the accidents on the NPPs with the reactor of WWER type and including the heat - mass exchange processes with low rates of the coolant, which is typical during the utilization of the passive safety systems, process during the accidents with a large leak, and also the complex intercommunicated processes in the reactor unit, passive safety systems and in the containment with the condition of long-term heat removal to the final absorber. KMS is being constructed at the Research Institute of Technology (NITI), Sosnovy Bor, Leningrad region, Russia. (orig.)

  3. Large-scale experimental facility for emergency condition investigation of a new generation NPP WWER-640 reactor with passive safety systems

    Energy Technology Data Exchange (ETDEWEB)

    Aniskevich, Y.N.; Vasilenko, V.A.; Zasukha, V.K.; Migrov, Y.A.; Khabensky, V.B. [Research Inst. of Technology NITI (Russian Federation)

    1997-12-31

    The creation of the large-scale integral experimental facility (KMS) is specified by the programme of the experimental investigations to justify the engineering decisions on the safety of the design of the new generation NPP with the reactor WWER-640. The construction of KMS in a full volume will allow to conduct experimental investigations of all physical phenomena and processes, practically, occurring during the accidents on the NPPs with the reactor of WWER type and including the heat - mass exchange processes with low rates of the coolant, which is typical during the utilization of the passive safety systems, process during the accidents with a large leak, and also the complex intercommunicated processes in the reactor unit, passive safety systems and in the containment with the condition of long-term heat removal to the final absorber. KMS is being constructed at the Research Institute of Technology (NITI), Sosnovy Bor, Leningrad region, Russia. (orig.). 5 refs.

  4. Survey on the technological development issues for large-scale methanol engine power generation plant; Ogata methanol engine hatsuden plant ni kansuru gijutsu kaihatsu kadai chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Based on the result of `Survey on the feasibility of large-scale methanol engine power generation plant` in fiscal 1992, concrete technological development issues were studied for its practical use, and the technological R & D scheme was prepared for large-scale methanol engine power plant featured by low NOx and high efficiency. Technological development issues of this plant were as follows: improvement of thermal efficiency, reduction of NOx emission, improvement of the reliability and durability of ignition and fuel injection systems, and reduction of vibration. As the economical effect of the technological development, the profitability of NOx control measures was compared between this methanol engine and conventional heavy oil diesel engines or gas engines. As a result, this engine was more economical than conventional engines. It was suggested that development of the equipment will be completed in nearly 4 years through every component study, single-cylinder model experiment and real engine test. 21 refs., 43 figs., 19 tabs.

  5. Large-scale experimental facility for emergency condition investigation of a new generation NPP WWER-640 reactor with passive safety systems

    Energy Technology Data Exchange (ETDEWEB)

    Aniskevich, Y N; Vasilenko, V A; Zasukha, V K; Migrov, Y A; Khabensky, V B [Research Inst. of Technology NITI (Russian Federation)

    1998-12-31

    The creation of the large-scale integral experimental facility (KMS) is specified by the programme of the experimental investigations to justify the engineering decisions on the safety of the design of the new generation NPP with the reactor WWER-640. The construction of KMS in a full volume will allow to conduct experimental investigations of all physical phenomena and processes, practically, occurring during the accidents on the NPPs with the reactor of WWER type and including the heat - mass exchange processes with low rates of the coolant, which is typical during the utilization of the passive safety systems, process during the accidents with a large leak, and also the complex intercommunicated processes in the reactor unit, passive safety systems and in the containment with the condition of long-term heat removal to the final absorber. KMS is being constructed at the Research Institute of Technology (NITI), Sosnovy Bor, Leningrad region, Russia. (orig.). 5 refs.

  6. Application of Vision Metrology to In-Orbit Measurement of Large Reflector Onboard Communication Satellite for Next Generation Mobile Satellite Communication

    Science.gov (United States)

    Akioka, M.; Orikasa, T.; Satoh, M.; Miura, A.; Tsuji, H.; Toyoshima, M.; Fujino, Y.

    2016-06-01

    Satellite for next generation mobile satellite communication service with small personal terminal requires onboard antenna with very large aperture reflector larger than twenty meters diameter because small personal terminal with lower power consumption in ground base requires the large onboard reflector with high antenna gain. But, large deployable antenna will deform in orbit because the antenna is not a solid dish but the flexible structure with fine cable and mesh supported by truss. Deformation of reflector shape deteriorate the antenna performance and quality and stability of communication service. However, in case of digital beam forming antenna with phased array can modify the antenna beam performance due to adjustment of excitation amplitude and excitation phase. If we can measure the reflector shape precisely in orbit, beam pattern and antenna performance can be compensated with the updated excitation amplitude and excitation phase parameters optimized for the reflector shape measured every moment. Softbank Corporation and National Institute of Information and Communications Technology has started the project "R&D on dynamic beam control technique for next generation mobile communication satellite" as a contracted research project sponsored by Ministry of Internal Affairs and Communication of Japan. In this topic, one of the problem in vision metrology application is a strong constraints on geometry for camera arrangement on satellite bus with very limited space. On satellite in orbit, we cannot take many images from many different directions as ordinary vision metrology measurement and the available area for camera positioning is quite limited. Feasibility of vision metrology application and general methodology to apply to future mobile satellite communication satellite is to be found. Our approach is as follows: 1) Development of prototyping simulator to evaluate the expected precision for network design in zero order and first order 2) Trial

  7. Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines.

    Directory of Open Access Journals (Sweden)

    Azhar R Hussain

    Full Text Available BACKGROUND: We have recently shown that deregulation PI3-kinase/AKT survival pathway plays an important role in pathogenesis of diffuse large B cell lymphoma (DLBCL. In an attempt to identify newer therapeutic agents, we investigated the role of Resveratrol (trans-3,4', 5-trihydroxystilbene, a naturally occurring polyphenolic compound on a panel of diffuse large B-cell lymphoma (DLBCL cells in causing inhibition of cell viability and inducing apoptosis. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the action of Resveratrol on DLBCL cells and found that Resveratrol inhibited cell viability and induced apoptosis by inhibition of constitutively activated AKT and its downstream targets via generation of reactive oxygen species (ROS. Simultaneously, Resveratrol treatment of DLBCL cell lines also caused ROS dependent upregulation of DR5; and interestingly, co-treatment of DLBCL with sub-toxic doses of TRAIL and Resveratrol synergistically induced apoptosis via utilizing DR5, on the other hand, gene silencing of DR5 abolished this effect. CONCLUSION/SIGNIFICANCE: Altogether, these data suggest that Resveratrol acts as a suppressor of AKT/PKB pathway leading to apoptosis via generation of ROS and at the same time primes DLBCL cells via up-regulation of DR5 to TRAIL-mediated apoptosis. These data raise the possibility that Resveratrol may have a future therapeutic role in DLBCL and possibly other malignancies with constitutive activation of the AKT/PKB pathway.

  8. The impact of increased interconnection on electricity systems with large penetrations of wind generation. A case study of Ireland and Great Britain

    International Nuclear Information System (INIS)

    Denny, E.; Tuohy, A.; Keane, A.; Flynn, D.; O'Malley, M.; Meibom, P.; Mullane, A.

    2010-01-01

    Increased interconnection has been highlighted as potentially facilitating the integration of wind generation in power systems by increasing the flexibility to balance the variable wind output. This paper utilizes a stochastic unit commitment model to simulate the impacts of increased interconnection for the island of Ireland with large penetrations of wind generation. The results suggest that increased interconnection should reduce average prices in Ireland, and the variability of those prices. The simulations also suggest that while increased interconnection may reduce carbon dioxide emissions in Ireland, Great Britain would experience an increase in emissions, resulting in total emissions remaining almost unchanged. The studies suggest that increased interconnection would not reduce excess wind generation. This is because under unit commitment techniques which incorporate wind power forecasts in the scheduling decisions, wind curtailment is minimal even with low levels of interconnection. As would be expected an increase in interconnection should improve system adequacy considerably with a significant reduction in the number of hours when the load and reserve constraints are not met. (author)

  9. Drosophila type II neuroblast lineages keep Prospero levels low to generate large clones that contribute to the adult brain central complex

    Directory of Open Access Journals (Sweden)

    Drummond Michael L

    2010-10-01

    Full Text Available Abstract Tissue homeostasis depends on the ability of stem cells to properly regulate self-renewal versus differentiation. Drosophila neural stem cells (neuroblasts are a model system to study self-renewal and differentiation. Recent work has identified two types of larval neuroblasts that have different self-renewal/differentiation properties. Type I neuroblasts bud off a series of small basal daughter cells (ganglion mother cells that each generate two neurons. Type II neuroblasts bud off small basal daughter cells called intermediate progenitors (INPs, with each INP generating 6 to 12 neurons. Type I neuroblasts and INPs have nuclear Asense and cytoplasmic Prospero, whereas type II neuroblasts lack both these transcription factors. Here we test whether Prospero distinguishes type I/II neuroblast identity or proliferation profile, using several newly characterized Gal4 lines. We misexpress prospero using the 19H09-Gal4 line (expressed in type II neuroblasts but no adjacent type I neuroblasts or 9D11-Gal4 line (expressed in INPs but not type II neuroblasts. We find that differential prospero expression does not distinguish type I and type II neuroblast identities, but Prospero regulates proliferation in both type I and type II neuroblast lineages. In addition, we use 9D11 lineage tracing to show that type II lineages generate both small-field and large-field neurons within the adult central complex, a brain region required for locomotion, flight, and visual pattern memory.

  10. High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery.

    Science.gov (United States)

    Turchetto, Jeremy; Sequeira, Ana Filipa; Ramond, Laurie; Peysson, Fanny; Brás, Joana L A; Saez, Natalie J; Duhoo, Yoan; Blémont, Marilyne; Guerreiro, Catarina I P D; Quinton, Loic; De Pauw, Edwin; Gilles, Nicolas; Darbon, Hervé; Fontes, Carlos M G A; Vincentelli, Renaud

    2017-01-17

    Animal venoms are complex molecular cocktails containing a wide range of biologically active disulphide-reticulated peptides that target, with high selectivity and efficacy, a variety of membrane receptors. Disulphide-reticulated peptides have evolved to display improved specificity, low immunogenicity and to show much higher resistance to degradation than linear peptides. These properties make venom peptides attractive candidates for drug development. However, recombinant expression of reticulated peptides containing disulphide bonds is challenging, especially when associated with the production of large libraries of bioactive molecules for drug screening. To date, as an alternative to artificial synthetic chemical libraries, no comprehensive recombinant libraries of natural venom peptides are accessible for high-throughput screening to identify novel therapeutics. In the accompanying paper an efficient system for the expression and purification of oxidized disulphide-reticulated venom peptides in Escherichia coli is described. Here we report the development of a high-throughput automated platform, that could be adapted to the production of other families, to generate the largest ever library of recombinant venom peptides. The peptides were produced in the periplasm of E. coli using redox-active DsbC as a fusion tag, thus allowing the efficient formation of correctly folded disulphide bridges. TEV protease was used to remove fusion tags and recover the animal venom peptides in the native state. Globally, within nine months, out of a total of 4992 synthetic genes encoding a representative diversity of venom peptides, a library containing 2736 recombinant disulphide-reticulated peptides was generated. The data revealed that the animal venom peptides produced in the bacterial host were natively folded and, thus, are putatively biologically active. Overall this study reveals that high-throughput expression of animal venom peptides in E. coli can generate large

  11. Revolutionizing Our Understanding of AGN Feedback and its Importance to Galaxy Evolution in the Era of the Next Generation Very Large Array

    Science.gov (United States)

    Nyland, K.; Harwood, J. J.; Mukherjee, D.; Jagannathan, P.; Rujopakarn, W.; Emonts, B.; Alatalo, K.; Bicknell, G. V.; Davis, T. A.; Greene, J. E.; Kimball, A.; Lacy, M.; Lonsdale, Carol; Lonsdale, Colin; Maksym, W. P.; Molnár, D. C.; Morabito, L.; Murphy, E. J.; Patil, P.; Prandoni, I.; Sargent, M.; Vlahakis, C.

    2018-05-01

    Energetic feedback by active galactic nuclei (AGNs) plays an important evolutionary role in the regulation of star formation on galactic scales. However, the effects of this feedback as a function of redshift and galaxy properties such as mass, environment, and cold gas content remain poorly understood. The broad frequency coverage (1 to 116 GHz), high sensitivity (up to ten times higher than the Karl G. Jansky Very Large Array), and superb angular resolution (maximum baselines of at least a few hundred kilometers) of the proposed next-generation Very Large Array (ngVLA) are uniquely poised to revolutionize our understanding of AGNs and their role in galaxy evolution. Here, we provide an overview of the science related to AGN feedback that will be possible in the ngVLA era and present new continuum ngVLA imaging simulations of resolved radio jets spanning a wide range of intrinsic extents. We also consider key computational challenges and discuss exciting opportunities for multiwavelength synergy with other next-generation instruments, such as the Square Kilometer Array and the James Webb Space Telescope. The unique combination of high-resolution, large collecting area, and wide frequency range will enable significant advancements in our understanding of the effects of jet-driven feedback on sub-galactic scales, particularly for sources with extents of a few parsec to a few kiloparsec, such as young and/or lower-power radio AGNs, AGNs hosted by low-mass galaxies, radio jets that are interacting strongly with the interstellar medium of the host galaxy, and AGNs at high redshift.

  12. PeptideNavigator: An interactive tool for exploring large and complex data sets generated during peptide-based drug design projects.

    Science.gov (United States)

    Diller, Kyle I; Bayden, Alexander S; Audie, Joseph; Diller, David J

    2018-01-01

    There is growing interest in peptide-based drug design and discovery. Due to their relatively large size, polymeric nature, and chemical complexity, the design of peptide-based drugs presents an interesting "big data" challenge. Here, we describe an interactive computational environment, PeptideNavigator, for naturally exploring the tremendous amount of information generated during a peptide drug design project. The purpose of PeptideNavigator is the presentation of large and complex experimental and computational data sets, particularly 3D data, so as to enable multidisciplinary scientists to make optimal decisions during a peptide drug discovery project. PeptideNavigator provides users with numerous viewing options, such as scatter plots, sequence views, and sequence frequency diagrams. These views allow for the collective visualization and exploration of many peptides and their properties, ultimately enabling the user to focus on a small number of peptides of interest. To drill down into the details of individual peptides, PeptideNavigator provides users with a Ramachandran plot viewer and a fully featured 3D visualization tool. Each view is linked, allowing the user to seamlessly navigate from collective views of large peptide data sets to the details of individual peptides with promising property profiles. Two case studies, based on MHC-1A activating peptides and MDM2 scaffold design, are presented to demonstrate the utility of PeptideNavigator in the context of disparate peptide-design projects. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. FY 1998 Report on development of large-scale wind power generation systems. Part 1. Operational research on large-scale wind power generation systems; 1998 nendo ogata furyoku hatsuden system kaihatsu seika hokokusho. 1. Ogata furyoku hatsuden system no unten kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The research and development project is implemented for large-scale wind power generation systems, and the FY 1998 results are reported. In the FY 1998, a slip property variable generator is actually mounted on the wind power generator, to conduct various types of demonstration tests. The reliability validation tests include microstructure examinations, fatigue tests and fatigue strength tests to predict residual strength in the blade. It is confirmed that the blade has a sufficient residual strength. The performance validation tests include continuous measurement of power outputs and wind velocities, and analysis of the output fluctuations. The power output performance during winter when the west wind prevails is higher than designed. In the tests for evaluating the characteristics of the system on which a slip property variable generator is mounted, the output smoothing effect is confirmed in a range beyond the rated output. The wind power generation system is continuously operated, to accumulate the operational data for, e.g., capacity factor, operating time rate, and system failure status. The FY 1998 results are 920,000kWh as the output and 21% as capacity factor. The other items investigate include aerodynamic noise reduction countermeasures, fatigue life of the wind turbine blades, economics of wind power generation, and dismantling and reuse of the wind turbines. (NEDO)

  14. Design of large permanent magnetized synchronous electric machines: Low speed, high torque machines - generator for direct driven wind turbine - motor for rim driven thruster

    Energy Technology Data Exchange (ETDEWEB)

    Kroevel, Oeystein

    2011-02-15

    This work presents the design of two prototype permanent magnetized electric machines for two different applications where large permanent magnet machines might be used. Existing technology have been used as the fundament for new design and adapted to new applications, contributing, hopefully, to the development of better and more environmental friendly energy conversion. The first application presented is represented with a prototype made in cooperation with the industry in which a PM-motor is integrated into a propeller unit. Both because of the industrial connection, and the integration between the PM-motor and the propeller, the choices made for the PM-motor are conservative trying to reduce the risk. The direct rim driven thruster prototype includes a surface mounted radial flux permanent magnet machine (SM RFPM) with fractional slot winding with a q around 1. Other engineering features were introduced to make the integration of propeller and motor feasible, but without the PM-machine the thruster would not have reached the performance demand. An important part of the project was to show that the SM RFPM enables this solution, providing high performance with a large air gap. The prototype has been tested in sea, under harsh conditions, and even though the magnets have been exposed directly to sea water and been visible corroded, the electric motor still performs well within the specifications. The second application is represented with a prototype PM-generator for wind turbines. This is an example of a new, very low speed high torque machine. The generator is built to test phenomena regarding concentrated coils, and as opposed to the first application, being a pure academic university project, its success is not connected to its performance, but with the prototype's ability to expose the phenomena in question. The prototype, or laboratory model, of the generator for direct driven wind turbines features SM RFPM with concentrated coils (CC). An opportunity

  15. Techno-economic feasibility of hybrid diesel/PV/wind/battery electricity generation systems for non-residential large electricity consumers under southern Iran climate conditions

    International Nuclear Information System (INIS)

    Baneshi, Mehdi; Hadianfard, Farhad

    2016-01-01

    Highlights: • A hybrid electricity generation system for a large electricity consumer was studied. • The PV and wind electricity potentials under given climate conditions were evaluated. • Technical, economical, and environmental issues of different systems were discussed. • The optimum configuration of components was obtained. • The impacts of governmental incentives on economic viability of systems were examined. - Abstract: This paper aims to study the techno-economical parameters of a hybrid diesel/PV/wind/battery power generation system for a non-residential large electricity consumer in the south of Iran. As a case study, the feasibility of running a hybrid system to meet a non-residential community’s load demand of 9911 kWh daily average and 725 kW peak load demand was investigated. HOMER Pro software was used to model the operation of the system and to identify the appropriate configuration of it based on comparative technical, economical, and environmental analysis. Both stand alone and grid connected systems were modeled. The impacts of annual load growth and governmental energy policies such as providing low interest loan to renewable energy projects, carbon tax, and modifying the grid electricity price on viability of the system were discussed. Results show that for off-grid systems the cost of electricity (COE) and the renewable fraction of 9.3–12.6 ₵/kWh and 0–43.9%, respectively, are achieved with photovoltaic (PV) panel, wind turbine, and battery sizes of 0–1000 kW, 0–600 kW, and 1300 kWh, respectively. For on grid systems without battery storage the range of COE and renewable fraction are 5.7–8.4 ₵/kWh and 0–53%, respectively, for the same sizes of PV panel and wind turbine.

  16. SU-E-I-20: Comprehensive Quality Assurance Test of Second Generation Toshiba Aquilion Large Bore CT Simulator Based On AAPM TG-66 Recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, D [Toshiba America Medical Systems, Tustin, CA (United States)

    2015-06-15

    Purpose: AAPM radiation therapy committee task group No. 66 (TG-66) published a report which described a general approach to CT simulator QA. The report outlines the testing procedures and specifications for the evaluation of patient dose, radiation safety, electromechanical components, and image quality for a CT simulator. The purpose of this study is to thoroughly evaluate the performance of a second generation Toshiba Aquilion Large Bore CT simulator with 90 cm bore size (Toshiba, Nasu, JP) based on the TG-66 criteria. The testing procedures and results from this study provide baselines for a routine QA program. Methods: Different measurements and analysis were performed including CTDIvol measurements, alignment and orientation of gantry lasers, orientation of the tabletop with respect to the imaging plane, table movement and indexing accuracy, Scanogram location accuracy, high contrast spatial resolution, low contrast resolution, field uniformity, CT number accuracy, mA linearity and mA reproducibility using a number of different phantoms and measuring devices, such as CTDI phantom, ACR image quality phantom, TG-66 laser QA phantom, pencil ion chamber (Fluke Victoreen) and electrometer (RTI Solidose 400). Results: The CTDI measurements were within 20% of the console displayed values. The alignment and orientation for both gantry laser and tabletop, as well as the table movement and indexing and scanogram location accuracy were within 2mm as specified in TG66. The spatial resolution, low contrast resolution, field uniformity and CT number accuracy were all within ACR’s recommended limits. The mA linearity and reproducibility were both well below the TG66 threshold. Conclusion: The 90 cm bore size second generation Toshiba Aquilion Large Bore CT simulator that comes with 70 cm true FOV can consistently meet various clinical needs. The results demonstrated that this simulator complies with the TG-66 protocol in all aspects including electromechanical component

  17. New generation pharmacogenomic tools: a SNP linkage disequilibrium Map, validated SNP assay resource, and high-throughput instrumentation system for large-scale genetic studies.

    Science.gov (United States)

    De La Vega, Francisco M; Dailey, David; Ziegle, Janet; Williams, Julie; Madden, Dawn; Gilbert, Dennis A

    2002-06-01

    Since public and private efforts announced the first draft of the human genome last year, researchers have reported great numbers of single nucleotide polymorphisms (SNPs). We believe that the availability of well-mapped, quality SNP markers constitutes the gateway to a revolution in genetics and personalized medicine that will lead to better diagnosis and treatment of common complex disorders. A new generation of tools and public SNP resources for pharmacogenomic and genetic studies--specifically for candidate-gene, candidate-region, and whole-genome association studies--will form part of the new scientific landscape. This will only be possible through the greater accessibility of SNP resources and superior high-throughput instrumentation-assay systems that enable affordable, highly productive large-scale genetic studies. We are contributing to this effort by developing a high-quality linkage disequilibrium SNP marker map and an accompanying set of ready-to-use, validated SNP assays across every gene in the human genome. This effort incorporates both the public sequence and SNP data sources, and Celera Genomics' human genome assembly and enormous resource ofphysically mapped SNPs (approximately 4,000,000 unique records). This article discusses our approach and methodology for designing the map, choosing quality SNPs, designing and validating these assays, and obtaining population frequency ofthe polymorphisms. We also discuss an advanced, high-performance SNP assay chemisty--a new generation of the TaqMan probe-based, 5' nuclease assay-and high-throughput instrumentation-software system for large-scale genotyping. We provide the new SNP map and validation information, validated SNP assays and reagents, and instrumentation systems as a novel resource for genetic discoveries.

  18. Large-amplitude mesospheric response to an orographic wave generated over the Southern Ocean Auckland Islands (50.7°S) during the DEEPWAVE project

    Science.gov (United States)

    Pautet, P.-D.; Taylor, M. J.; Fritts, D. C.; Bossert, K.; Williams, B. P.; Broutman, D.; Ma, J.; Eckermann, S. D.; Doyle, J. D.

    2016-02-01

    The Deep Propagating Gravity Wave Experiment (DEEPWAVE) project was conducted over New Zealand and the surrounding regions during June and July 2014, to more fully understand the generation, propagation, and effects of atmospheric gravity waves. A large suite of instruments collected data from the ground to the upper atmosphere (~100 km), with several new remote-sensing instruments operating on board the NSF Gulfstream V (GV) research aircraft, which was the central measurement platform of the project. On 14 July, during one of the research flights (research flight 23), a spectacular event was observed as the GV flew in the lee of the sub-Antarctic Auckland Islands (50.7°S). An apparent "ship wave" pattern was imaged in the OH layer (at ~83.5 km) by the Utah State University Advanced Mesospheric Temperature Mapper and evolved significantly over four successive passes spanning more than 4 h. The waves were associated with orographic forcing generated by relatively strong (15-20 m/s) near-surface wind flowing over the rugged island topography. The mountain wave had an amplitude T' ~ 10 K, a dominant horizontal wavelength ~40 km, achieved a momentum flux exceeding 300 m2 s-2, and eventually exhibited instability and breaking at the OH altitude. This case of deep mountain wave propagation demonstrates the potential for strong responses in the mesosphere arising from a small source under suitable propagation conditions and suggests that such cases may be more common than previously believed.

  19. Prevalence, correlates, and impact of coronary calcification on adverse events following PCI with newer-generation DES: Findings from a large multiethnic registry.

    Science.gov (United States)

    Copeland-Halperin, Robert S; Baber, Usman; Aquino, Melissa; Rajamanickam, Anitha; Roy, Swathi; Hasan, Choudhury; Barman, Nitin; Kovacic, Jason C; Moreno, Pedro; Krishnan, Prakash; Sweeny, Joseph M; Mehran, Roxana; Dangas, George; Kini, Annapoorna S; Sharma, Samin K

    2018-04-01

    We sought to determine the prevalence, predictors, and clinical impact of target lesion calcification in patients undergoing percutaneous coronary intervention (PCI) with newer generation drug-eluting stents (DES) and devices. Coronary calcification is independently associated with adverse outcomes following PCI. While newer DES and contemporary devices are considered safer and more efficacious, their influence on outcomes following PCI of heavily calcified lesions is unknown. We performed a retrospective analysis of a large, multiethnic cohort of patients undergoing PCI with new generation DES at an academic center between 2009 and 2013. Coronary calcification was qualitatively assessed as none/mild, moderate, or severe. Independent demographic, clinical, and anatomic predictors of moderate/severe calcification were identified using logistic regression. Associations between coronary calcification and 1-year MACE (death, myocardial infarction, or target vessel revascularization) were examined using Cox modeling. Compared to patients with none/mild (n = 10,180; 82.0%), those with moderate (n = 1,271; 10.0%) or severe (n = 994; 8.0%) calcification were older, more often Caucasian, had more complex target lesions, and worse renal function. The strongest demographic, clinical, and anatomic correlates of moderate/severe calcification were age, Caucasian race, renal dysfunction, lesion length, and left main location. Unadjusted MACE rates among those with none/mild, moderate, and severe calcification were 8.3, 14.6, and 17.8%, respectively (P < 0.001). After multivariable adjustment, the hazard ratio (95% CI) for MACE associated with moderate or severe coronary calcification was 1.63. Target lesion calcification remains independently associated with adverse outcomes in patients treated with newer generation DES and modern devices. © 2017 Wiley Periodicals, Inc.

  20. Reliable and inexpensive expression of large, tagged, exogenous proteins in murine bone marrow-derived macrophages using a second generation lentiviral system

    Directory of Open Access Journals (Sweden)

    Matthew R. Miller

    2015-08-01

    Full Text Available Over the past two decades, researchers have struggled to efficiently express foreign DNA in primary macrophages, impeding research progress. The applications of lipofection, electroporation, microinjection, and viral-mediated transfer typically result in disruptions in macrophage differentiation and function, low expression levels of exogenous proteins, limited efficiency and high cell mortality. In this report, after extensive optimization, we present a method of expressing large tagged proteins at high efficiency, consistency, and low cost using lentiviral infection. This method utilizes laboratory-propagated second generation plasmids to produce efficient virus that can be stored for later use. The expression of proteins up to 150 kDa in size is achieved in 30–70% of cells while maintaining normal macrophage differentiation and morphology as determined by fluorescence microscopy and Western blot analysis. This manuscript delineates the reagents and methods used to produce lentivirus to express exogenous DNA in murine bone marrow-derived macrophages sufficient for single cell microscopy as well as functional assays requiring large numbers of murine bone marrow-derived macrophages.

  1. Loss of the ability to generate large burst-forming unit-like megakaryocytic colonies from thawed cord blood in semisolid cultures after short term suspension culture.

    Science.gov (United States)

    Eskola, M; Bäckman, S; Möttönen, S; Kekomäki, R

    2015-04-01

    Total colony-forming cells from thawed cord blood units (CBUs) include megakaryocytic colony-forming units (CFU-Mks), which survive the freezing process. The aim of this study was to evaluate whether different megakaryocytic progenitors from unseparated CBUs survive the freezing process and a short-term liquid culture. Thawed samples of CBUs were cultured in liquid medium. During the cultures, serial samples were drawn to assess the growth of different megakaryocytic progenitors in a semisolid collagen medium with identical cytokines as in the liquid medium. Megakaryocytic cells were detected using immunohistochemistry and flow cytometry. In suspension culture, the megakaryocytic progenitors almost completely lost the ability to generate large (burst-forming unit-like, BFU-like) megakaryocytic colonies in semisolid cultures (large colonies, median count per chamber d0: 7.25 vs. d7: 1.5; P culture in suspension resulted in the decline of small colonies as well (d7: 16.0 vs. d14: 5.75; P = 0.0088). Total CFU-Mk count declined from 23.3 (range 12.5-34.0) at d0 to 7.25 (range 1.0-13.5) at d14 (P culture after a short suspension culture. Small CFU-Mks were observed throughout the cultures. It may be that the BFU-Mk colonies matured and acquired CFU-Mk behaviour. © 2014 International Society of Blood Transfusion.

  2. Generation of particles with large transverse momenta in π--p- and π-12C-interactions at 40 GeV/c

    International Nuclear Information System (INIS)

    Jordanova, Yu.; Lyubimov, V.; Mitova, S.; Penev, V.N.; Shklovskaya, A.

    1981-01-01

    The generation of a particle with transverse momenta Psub(transverse)>0.8 GeV/c in π - -p- and π - - 12 C-interactions with a π - -meson beam at a momentum Psub(π)=40 GeV/c in a two-meter propan chamber is investigated. Analyses of the secondary particle correlations produced in the interactions, in which the emitted hadron or group of hadrons have large transverse momenta, are carried out. In the investigated interactions the secondary particle momenta are measured with an accuracy not less than 30%. In the experimental data treatment of the π - - 12 C-collisions the interactions of π - -mesons with the quasifree nucleons of 12 C-nucleus are taken into account on the basis of the multiperipherical model. The experimental data analyses indicate that: 1) In the events with one or more secondary particles having large momenta Psub(transverse)>0.8 GeV/c the asymmetric correlations increase for both π - -p- and π - - 12 C-interactions; 2) Most correlated pairs of secondary particles having Psub(transverse)>0.8 GeV/c are produced with an almost equal rapidity and transverse momenta; 3) The presence of the secondary particles with large transverse momenta does not influence the resonance formation (in particular rho 0 -meson); 4) The effective mass distribution of the two secondary particles with Psub(transverse)>0.8 GeV/c has a broad peak at about 2 GeV/c

  3. Thermal load determination in the mixing TEE impacted by a turbulent flow generated by two fluids at large gap of temperature

    International Nuclear Information System (INIS)

    Braillard, O.

    2005-01-01

    A 304L mixing tee mock-up is instrumented to assess the fluctuating temperature in the mixing area generated by two fluids (water) at large gap of temperature meet. The turbulent mixing layer impacts the structure wall and creates stresses, which lead to the damages. The case studied in this paper corresponds to the 'swinging streak' within a flow rate ratio of 25 %. The instrumentation is specifically planned to measure the fluctuating temperature in the fluid close to the internal skin and inside the wall too. This experiment is performed using a new sensor 'fluxmeter' which is non intrusive and typically designed to catch the fluctuation without any signal attenuation, within a frequency range 0-25Hz. The facility called 'Fatherino' supplies an available delta T of 70 degree C in water at 4 m/s mixture velocity in a mixing tee mock-up 50 mm in diameter. The flow features generate a large turbulent flow in the mixing layer and favour the heat flux transfer to the wall. By applying an inverse heat conduction method applied to the output data given by the fluxmeter, both the heat flux is deduced and the temperature (mean and fluctuating values) at the internal surface can be accurately determined. In addition, a calculation using the Trio U code (thermal hydraulic code) within the large eddy simulation module is computed to assess the fluid temperature distribution in the mixing area close to the internal surface. The output data in mean and standard deviation are compared with the Fatherino measurements. The comparison consists in analysing the main parameters as the mean and standard deviation in the fluid along the main axis and in a circumferential view. The mixing layer geometry and the frequency of the fluctuation are also analysed. These experiments added to the calculation allow us improving the state of the knowledge in the mixing tees and the thermal load to be used in the industrial mixing tees in operating for the long lifetime assessment or for the

  4. Increased expression of IRF8 in tumor cells inhibits the generation of Th17 cells and predicts unfavorable survival of diffuse large B cell lymphoma patients.

    Science.gov (United States)

    Zhong, Weijie; Xu, Xin; Zhu, Zhigang; Du, Qinghua; Du, Hong; Yang, Li; Ling, Yanying; Xiong, Huabao; Li, Qingshan

    2017-07-25

    The immunological pathogenesis of diffuse large B cell lymphoma (DLBCL) remains elusive. Searching for new prognostic markers of DLBCL is a crucial focal point for clinical scientists. The aim of the present study was to examine the prognostic value of interferon regulatory factor 8 (IRF8) expression and its effect on the development of Th17 cells in the tumor microenvironment of DLBCL patients. Flow cytometry, immunohistochemistry, and quantitative real-time PCR were used to detect the distribution of Th17 cells and related cytokines and IRF8 in tumor tissues from DLBCL patients. Two DLBCL cell lines (OCI-LY10 and OCI-LY1) with IRF8 knockdown or overexpression and two human B lymphoblast cell lines were co-cultured with peripheral blood mononuclear cells (PBMCs) in vitro to determine the effect of IRF8 on the generation of Th17 cells. Quantitative real-time PCR and Western blotting were used to investigate the involvement of retinoic acid receptor-related orphan receptor gamma t (RORγt) in the effect of IRF8 on Th17 cell generation. The survival of 67 DLBCL patients was estimated using the Kaplan-Meier method and log-rank analysis. The percentage of Th17 cells was lower in DLBCL tumor tissues than in PBMCs and corresponding adjacent benign tissues. Relative expression of interleukin (IL)-17A was lower, whereas that of interferon (IFN)-γ was higher in tumor tissues than in benign tissues. Co-culture with DLBCL cell lines inhibited the generation of Th17 cells in vitro. IRF8 upregulation was detected in DLBCL tumor tissues, and it was associated with decreased DLBCL patient survival. Investigation of the underlying mechanism suggested that IRF8 upregulation in DLBCL, through an unknown mechanism, inhibited Th17 cell generation by suppressing RORγt in neighboring CD4+ T cells. Tumor cells may express soluble or membrane-bound factors that inhibit the expression of RORγt in T cells within the tumor microenvironment. Our findings suggest that IRF8 expression could

  5. Optimising generators

    Energy Technology Data Exchange (ETDEWEB)

    Guerra, E.J.; Garcia, A.O.; Graffigna, F.M.; Verdu, C.A. (IMPSA (Argentina). Generators Div.)

    1994-11-01

    A new computer tool, the ARGEN program, has been developed for dimensioning large hydroelectric generators. This results in better designs, and reduces calculation time for engineers. ARGEN performs dimensional tailoring of salient pole synchronous machines in generators, synchronous condensers, and generator-motors. The operation and uses of ARGEN are explained and its advantages are listed in this article. (UK)

  6. FY 1998 Report on development of large-scale wind power generation systems. Feasibility study on development of new technologies for wind power generation (Study on the development of wind power generation); 1998 nendo ogata furyoku hatsuden system kaihatsu. Furyoku hatsuden shingijutsu kaihatsu kanosei chosa (furyoku hatsuden gijutsu ni kansuru kaihatsu doko chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This survey is designed to analyze, e.g., current status of large-scale wind power generation devices/system technologies and development trends worldwide, and to make predictions about future developments, in an effort to contribute to advancements in new technology for wind power generation systems in Japan. The international R and D cooperation programs promoted by IEA and EU have helped the participants produce a number of good results at lower costs. The European countries have developed the wind power generation industries in each area, promoted by the governmental subsidy policies, and are leading the world. The system is becoming larger, from around an average unit capacity of 250kW in the beginning of the 90's to 600kW now, reducing the cost by the scale merit. The improved computer capacity has made it possible to more easily analyze the complicated rotor aerodynamics, structural dynamics, wind characteristics and other factors related to wind power generation systems. The future R and D directions will include world standards for large-scale wind turbines, advancements in wind farm technologies, offshore wind power generation systems, advancement in design technologies, and new concepts for wind power turbine designs, e.g., floating wind turbine. (NEDO)

  7. Thorough Chemical Decontamination with the MEDOC Process : Batch Treatment of Dismantled Pieces or Loop Treatment of Large Components Such as the BR3 Steam Generator and Pressurizer

    International Nuclear Information System (INIS)

    Ponnet, M.; Klein, M.; Massaut, V.; Davain, H.; Aleton, G.

    2003-01-01

    The dismantling of the BR3-PWR reactor leads to the production of large masses of contaminated metallic pieces, including structural materials, primary pipings, tanks and heat exchangers. One of our main objectives is to demonstrate that we can minimize the volume of radioactive waste in an economical way, by the use of alternative waste routes, such as the clearance of materials after thorough decontamination. The SCKoCEN uses its own developed chemical decontamination process, so-called MEDOC (Metal Decontamination by Oxidation with Cerium), based on the use of cerium IV as strong oxidant in sulphuric acid with continuous regeneration using ozone. An industrial installation has been designed and constructed in close collaboration with Framatome-ANP (France). This installation started operation in September 1999 for the treatment of the metallic pieces arising from the dismantling of the BR3 reactor. Since then, more than 25 tons of contaminated material including primary pipes have been treated batchwise with success. 75 % of material could be directly cleared after treatment (Activity lower than 0.1 Bq/g for 60Co) and the other 25% free released after melting activity. The SCKoCEN performed in April 2002 the closed loop decontamination of the BR3 Steam Generator by connection of the MEDOC plant after few adaptations. The decontamination was done within 30 cycles in 3 weeks with consecutive steps like decontamination steps (injection of the solution into the SG) and regeneration steps with ozone. In total, 60 hours of decontamination at 70 C and 130 hours of regeneration were needed to reach the objectives. The tube bundle (600 m2) was attacked and about 10 (micro)m representing more than 41 kg of stainless steel and 2.06 GBq of 60Co was dissolved into the solution. The residual contamination measurements made directly into the water box are still going on, however it seems that the objective to reach the free release criteria after melting is achieved. The next

  8. Large Eddy Simulations of a Premixed Jet Combustor Using Flamelet-Generated Manifolds: Effects of Heat Loss and Subgrid-Scale Models

    KAUST Repository

    Hernandez Perez, Francisco E.; Lee, Bok Jik; Im, Hong G.; Fancello, Alessio; Donini, Andrea; van Oijen, Jeroen A.; de Goey, Philip H.

    2017-01-01

    Large eddy simulations of a turbulent premixed jet flame in a confined chamber were conducted using the flamelet-generated manifold technique for chemistry tabulation. The configuration is characterized by an off-center nozzle having an inner diameter of 10 mm, supplying a lean methane-air mixture with an equivalence ratio of 0.71 and a mean velocity of 90 m/s, at 573 K and atmospheric pressure. Conductive heat loss is accounted for in the manifold via burner-stabilized flamelets and the subgrid-scale (SGS) turbulencechemistry interaction is modeled via presumed probability density functions. Comparisons between numerical results and measured data show that a considerable improvement in the prediction of temperature is achieved when heat losses are included in the manifold, as compared to the adiabatic one. Additional improvement in the temperature predictions is obtained by incorporating radiative heat losses. Moreover, further enhancements in the LES predictions are achieved by employing SGS models based on transport equations, such as the SGS turbulence kinetic energy equation with dynamic coefficients. While the numerical results display good agreement up to a distance of 4 nozzle diameters downstream of the nozzle exit, the results become less satisfactory along the downstream, suggesting that further improvements in the modeling are required, among which a more accurate model for the SGS variance of progress variable can be relevant.

  9. Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing.

    Science.gov (United States)

    Ito, Masaoki; Miyata, Yoshihiro; Hirano, Shoko; Kimura, Shingo; Irisuna, Fumiko; Ikeda, Kyoko; Kushitani, Kei; Tsutani, Yasuhiro; Ueda, Daisuke; Tsubokawa, Norifumi; Takeshima, Yukio; Okada, Morihito

    2017-12-12

    Small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC) of the lung are classified as variants of endocrine carcinoma and subdivided into pure or combined type. Clinical benefit of target therapy has not been established in these tumors. This study aimed to compare genetic and clinicopathological features between SCLC and LCNEC or pure and combined types, and explore the possibility of target therapy using next-generation sequencing. In 13 SCLC and 22 LCNEC cases, 72 point mutations, 19 deletions, and 3 insertions were detected. As therapeutically targetable variants, mutations in EGFR (L858R), KRAS (G12D, G12A, G12V), and PIK3CA (E545K) were detected in 5 cases. The case harboring EGFR mutation showed response to EGFR-tyrosine kinase inhibitor. However, there are no clinicopathological features associated with therapeutically targetable cases. And there was no significant genetic feature between SCLC and LCNEC or pure and combined types. In conclusion, although patients with SCLC and LCNEC may benefit from target therapy, they were not identifiable by clinicopathologic background. And there was not significant genetic difference between SCLC and LCNEC, including between pure and combined types. Classifying SCLC and LCNEC in same category is reasonable. However, distinguishing the pure type from combined type was not validated. Comprehensive genetic analysis should be performed to detect targetable variants in any type of SCLC and LCNEC.

  10. Evidence for the role of horizontal transfer in generating pVT1, a large mosaic conjugative plasmid from the clam pathogen, Vibrio tapetis.

    Directory of Open Access Journals (Sweden)

    Gaël Erauso

    Full Text Available The marine bacterium Vibrio tapetis is the causative agent of the brown ring disease, which affects the clam Ruditapes philippinarum and causes heavy economic losses in North of Europe and in Eastern Asia. Further characterization of V. tapetis isolates showed that all the investigated strains harbored at least one large plasmid. We determined the sequence of the 82,266 bp plasmid pVT1 from the CECT4600(T reference strain and analyzed its genetic content. pVT1 is a mosaic plasmid closely related to several conjugative plasmids isolated from Vibrio vulnificus strains and was shown to be itself conjugative in Vibrios. In addition, it contains DNA regions that have similarity with several other plasmids from marine bacteria (Vibrio sp., Shewanella sp., Listonella anguillarum and Photobacterium profundum. pVT1 contains a number of mobile elements, including twelve Insertion Sequences or inactivated IS genes and an RS1 phage element related to the CTXphi phage of V. cholerae. The genetic organization of pVT1 underscores an important role of horizontal gene transfer through conjugative plasmid shuffling and transposition events in the acquisition of new genetic resources and in generating the pVT1 modular organization. In addition, pVT1 presents a copy number of 9, relatively high for a conjugative plasmid, and appears to belong to a new type of replicon, which may be specific to Vibrionaceae and Shewanelleacae.

  11. Polyfunctional inorganic-organic hybrid materials: an unusual kind of NLO active layered mixed metal oxalates with tunable magnetic properties and very large second harmonic generation.

    Science.gov (United States)

    Cariati, Elena; Macchi, Roberto; Roberto, Dominique; Ugo, Renato; Galli, Simona; Casati, Nicola; Macchi, Piero; Sironi, Angelo; Bogani, Lapo; Caneschi, Andrea; Gatteschi, Dante

    2007-08-01

    Mixed M(II)/M(III) metal oxalates, as "stripes" connected through strong hydrogen bonding by para-dimethylaminobenzaldeide (DAMBA) and water, form an organic-inorganic 2D network that enables segregation in layers of the cationic organic NLO-phore trans-4-(4-dimethylaminostyryl)-1-methylpyridinium, [DAMS+]. The crystalline hybrid materials obtained have the general formula [DAMS]4[M2M'(C2O4)6].2DAMBA.2H2O (M = Rh, Fe, Cr; M' = Mn, Zn), and their overall three-dimensional packing is non-centrosymmetric and polar, therefore suitable for second harmonic generation (SHG). All the compounds investigated are characterized by an exceptional SHG activity, due both to the large molecular quadratic hyperpolarizability of [DAMS+] and to the efficiency of the crystalline network which organizes [DAMS+] into head-to-tail arranged J-type aggregates. The tunability of the pairs of metal ions allows exploiting also the magnetic functionality of the materials. Examples containing antiferro-, ferro-, and ferri-magnetic interactions (mediated by oxalato bridges) are obtained by coupling proper M(III) ions (Fe, Cr, Rh) with M(II) (Mn, Zn). This shed light on the role of weak next-nearest-neighbor interactions and main nearest-neighbor couplings along "stripes" of mixed M(II)/M(III) metal oxalates of the organic-inorganic 2D network, thus suggesting that these hybrid materials may display isotropic 1D magnetic properties along the mixed M(II)/M(III) metal oxalates "stripes".

  12. Large Eddy Simulations of a Premixed Jet Combustor Using Flamelet-Generated Manifolds: Effects of Heat Loss and Subgrid-Scale Models

    KAUST Repository

    Hernandez Perez, Francisco E.

    2017-01-05

    Large eddy simulations of a turbulent premixed jet flame in a confined chamber were conducted using the flamelet-generated manifold technique for chemistry tabulation. The configuration is characterized by an off-center nozzle having an inner diameter of 10 mm, supplying a lean methane-air mixture with an equivalence ratio of 0.71 and a mean velocity of 90 m/s, at 573 K and atmospheric pressure. Conductive heat loss is accounted for in the manifold via burner-stabilized flamelets and the subgrid-scale (SGS) turbulencechemistry interaction is modeled via presumed probability density functions. Comparisons between numerical results and measured data show that a considerable improvement in the prediction of temperature is achieved when heat losses are included in the manifold, as compared to the adiabatic one. Additional improvement in the temperature predictions is obtained by incorporating radiative heat losses. Moreover, further enhancements in the LES predictions are achieved by employing SGS models based on transport equations, such as the SGS turbulence kinetic energy equation with dynamic coefficients. While the numerical results display good agreement up to a distance of 4 nozzle diameters downstream of the nozzle exit, the results become less satisfactory along the downstream, suggesting that further improvements in the modeling are required, among which a more accurate model for the SGS variance of progress variable can be relevant.

  13. Electrical efficiency and renewable energy - Economical alternatives to large-scale power generation; Stromeffizienz und erneuerbare Energien - Wirtschaftliche alternative zu Grosskraftwerken

    Energy Technology Data Exchange (ETDEWEB)

    Oettli, B.; Hammer, S.; Moret, F.; Iten, R. [Infras, Zuerich (Switzerland); Nordmann, T. [TNC Consulting AG, Erlenbach (Switzerland)

    2010-05-15

    This final report for WWF Switzerland, Greenpeace Switzerland, the Swiss Energy Foundation SES, Pro Natura and the Swiss Cantons of Basel City and Geneva takes a look at the energy-relevant effects of the propositions made by Swiss electricity utilities for large-scale power generation. These proposals are compared with a strategy that proposes investments in energy-efficiency and the use of renewable sources of energy. The effects of both scenarios on the environment and the risks involved are discussed, as are the investments involved. The associated effects on the Swiss national economy are also discussed. For the efficiency and renewables scenario, two implementation variants are discussed: Inland investments and production are examined as are foreign production options and/or import from foreign countries. The methods used in the study are introduced and discussed. Investment and cost considerations, earnings and effects on employment are also reviewed. The report is completed with an extensive appendix which, amongst other things, includes potential reviews, cost estimates and a discussion on 'smart grids'

  14. Impact of Subgrid Scale Models and Heat Loss on Large Eddy Simulations of a Premixed Jet Burner Using Flamelet-Generated Manifolds

    Science.gov (United States)

    Hernandez Perez, Francisco E.; Im, Hong G.; Lee, Bok Jik; Fancello, Alessio; Donini, Andrea; van Oijen, Jeroen A.; de Goey, L. Philip H.

    2017-11-01

    Large eddy simulations (LES) of a turbulent premixed jet flame in a confined chamber are performed employing the flamelet-generated manifold (FGM) method for tabulation of chemical kinetics and thermochemical properties, as well as the OpenFOAM framework for computational fluid dynamics. The burner has been experimentally studied by Lammel et al. (2011) and features an off-center nozzle, feeding a preheated lean methane-air mixture with an equivalence ratio of 0.71 and mean velocity of 90 m/s, at 573 K and atmospheric pressure. Conductive heat loss is accounted for in the FGM tabulation via burner-stabilized flamelets and the subgrid-scale (SGS) turbulence-chemistry interaction is modeled via presumed filtered density functions. The impact of heat loss inclusion as well as SGS modeling for both the SGS stresses and SGS variance of progress variable on the numerical results is investigated. Comparisons of the LES results against measurements show a significant improvement in the prediction of temperature when heat losses are incorporated into FGM. While further enhancements in the LES results are accomplished by using SGS models based on transported quantities and/or dynamically computed coefficients as compared to the Smagorinsky model, heat loss inclusion is more relevant. This research was sponsored by King Abdullah University of Science and Technology (KAUST) and made use of computational resources at KAUST Supercomputing Laboratory.

  15. The Large Hadron Collider and the Super Proton Synchrotron at CERN as Tools to Generate Warm Dense Matter and Non–Ideal Plasmas

    CERN Document Server

    Tahir, N A; Shutov, A; Lomonosov, I V; Gryaznov, V; Piriz, A R; Deutsch, C; Fortov, V E

    2011-01-01

    The largest accelerator in the world, the Large Hadron Collider (LHC) at CERN, has entered into commission- ing phase. It is expected that when this impressive machine will become fully operational, it will generate two counter rotating 7 TeV/c proton beams that will be made to collide, leading to an unprecedented luminosity of 1034 cm−2s−1. Total energy stored in each LHC beam is about 362 MJ, sufficient to melt 500 kg copper. Safety of operation is a very critical issue when working with such extremely powerful beams. It is important to know the consequences of an accidental release of the beam energy in order to design protection system for the equipment. For this purpose we have carried out extensive numerical simulations of the interaction of one full LHC beam with copper and graphite targets which are materials of practical importance. Our calculations have shown that the LHC protons will penetrate up to about 35 m in solid copper and 10 m in solid graphite. A very interesting outcome of this work i...

  16. The Large Hadron Collider and the Super Proton Synchrotron at CERN as Tools to Generate Warm Dense Matter and Non-Ideal Plasmas

    CERN Document Server

    Tahir, N A; Deutsch, C; Gryaznov, V; Lomonosov, I V; Shutov, A; Piriz, A R; Fortov, V E; Geissel, H; Redmer, R

    2011-01-01

    The largest accelerator in the world, the Large Hadron Collider (LHC) at CERN, has entered into commissioning phase. It is expected that when this impressive machine will become fully operational, it will generate two counter rotating 7 TeV/c proton beams that will be made to collide, leading to an unprecedented luminosity of 10(34) cm(-2)s(-1). Total energy stored in each LHC beam is about 362 MJ, sufficient to melt 500 kg copper. Safety of operation is a very critical issue when working with such extremely powerful beams. It is important to know the consequences of an accidental release of the beam energy in order to design protection system for the equipment. For this purpose we have carried out extensive numerical simulations of the interaction of one full LHC beam with copper and graphite targets which are materials of practical importance. Our calculations have shown that the LHC protons will penetrate up to about 35 m in solid copper and 10 m in solid graphite. A very interesting outcome of this work i...

  17. Large intragenic deletion of CDC73 (exons 4-10) in a three-generation hyperparathyroidism-jaw tumor (HPT-JT) syndrome family.

    Science.gov (United States)

    Guarnieri, Vito; Seaberg, Raewyn M; Kelly, Catherine; Jean Davidson, M; Raphael, Simon; Shuen, Andrew Y; Baorda, Filomena; Palumbo, Orazio; Scillitani, Alfredo; Hendy, Geoffrey N; Cole, David E C

    2017-08-03

    Inactivating mutations of CDC73 cause Hyperparathyroidism-Jaw Tumour syndrome (HPT-JT), Familial Isolated Hyperparathyroidism (FIHP) and sporadic parathyroid carcinoma. We conducted CDC73 mutation analysis in an HPT-JT family and confirm carrier status of the proband's daughter. The proband had primary hyperparathyroidism (parathyroid carcinoma) and uterine leiomyomata. Her father and daughter had hyperparathyroidism (parathyroid adenoma) but no other manifestations of HPT-JT. CDC73 mutation analysis (sequencing of all 17 exons) and whole-genome copy number variation (CNV) analysis was done on leukocyte DNA of the three affecteds as well as the proband's unaffected sister. A novel deletion of exons 4 to 10 of CDC73 was detected by CNV analysis in the three affecteds. A novel insertion in the 5'UTR (c.-4_-11insG) that co-segregated with the deletion was identified. By in vitro assay the 5'UTR insertion was shown to significantly impair the expression of the parafibromin protein. Screening for the mutated CDC73 confirmed carrier status in the proband's daughter and the biochemistry and ultrasonography led to pre-emptive surgery and resolution of the hyperparathyroidism. A novel gross deletion mutation in CDC73 was identified in a three-generation HPT-JT family emphasizing the importance of including screening for large deletions in the molecular diagnostic protocol.

  18. Generation and analysis of large-scale expressed sequence tags (ESTs from a full-length enriched cDNA library of porcine backfat tissue

    Directory of Open Access Journals (Sweden)

    Lee Hae-Young

    2006-02-01

    Full Text Available Abstract Background Genome research in farm animals will expand our basic knowledge of the genetic control of complex traits, and the results will be applied in the livestock industry to improve meat quality and productivity, as well as to reduce the incidence of disease. A combination of quantitative trait locus mapping and microarray analysis is a useful approach to reduce the overall effort needed to identify genes associated with quantitative traits of interest. Results We constructed a full-length enriched cDNA library from porcine backfat tissue. The estimated average size of the cDNA inserts was 1.7 kb, and the cDNA fullness ratio was 70%. In total, we deposited 16,110 high-quality sequences in the dbEST division of GenBank (accession numbers: DT319652-DT335761. For all the expressed sequence tags (ESTs, approximately 10.9 Mb of porcine sequence were generated with an average length of 674 bp per EST (range: 200–952 bp. Clustering and assembly of these ESTs resulted in a total of 5,008 unique sequences with 1,776 contigs (35.46% and 3,232 singleton (65.54% ESTs. From a total of 5,008 unique sequences, 3,154 (62.98% were similar to other sequences, and 1,854 (37.02% were identified as having no hit or low identity (Sus scrofa. Gene ontology (GO annotation of unique sequences showed that approximately 31.7, 32.3, and 30.8% were assigned molecular function, biological process, and cellular component GO terms, respectively. A total of 1,854 putative novel transcripts resulted after comparison and filtering with the TIGR SsGI; these included a large percentage of singletons (80.64% and a small proportion of contigs (13.36%. Conclusion The sequence data generated in this study will provide valuable information for studying expression profiles using EST-based microarrays and assist in the condensation of current pig TCs into clusters representing longer stretches of cDNA sequences. The isolation of genes expressed in backfat tissue is the

  19. ANEMOS: Development of a next generation wind power forecasting system for the large-scale integration of onshore and offshore wind farms.

    Science.gov (United States)

    Kariniotakis, G.; Anemos Team

    2003-04-01

    Objectives: Accurate forecasting of the wind energy production up to two days ahead is recognized as a major contribution for reliable large-scale wind power integration. Especially, in a liberalized electricity market, prediction tools enhance the position of wind energy compared to other forms of dispatchable generation. ANEMOS, is a new 3.5 years R&D project supported by the European Commission, that resembles research organizations and end-users with an important experience on the domain. The project aims to develop advanced forecasting models that will substantially outperform current methods. Emphasis is given to situations like complex terrain, extreme weather conditions, as well as to offshore prediction for which no specific tools currently exist. The prediction models will be implemented in a software platform and installed for online operation at onshore and offshore wind farms by the end-users participating in the project. Approach: The paper presents the methodology of the project. Initially, the prediction requirements are identified according to the profiles of the end-users. The project develops prediction models based on both a physical and an alternative statistical approach. Research on physical models gives emphasis to techniques for use in complex terrain and the development of prediction tools based on CFD techniques, advanced model output statistics or high-resolution meteorological information. Statistical models (i.e. based on artificial intelligence) are developed for downscaling, power curve representation, upscaling for prediction at regional or national level, etc. A benchmarking process is set-up to evaluate the performance of the developed models and to compare them with existing ones using a number of case studies. The synergy between statistical and physical approaches is examined to identify promising areas for further improvement of forecasting accuracy. Appropriate physical and statistical prediction models are also developed for

  20. Constellation-X to Generation-X: evolution of large collecting area moderate resolution grazing incidence x-ray telescopes to larger area high-resolution adjustable optics

    Science.gov (United States)

    Reid, Paul B.; Cameron, Robert A.; Cohen, Lester; Elvis, Martin; Gorenstein, Paul; Jerius, Diab; Petre, Robert; Podgorski, William A.; Schwartz, Daniel A.; Zhang, William W.

    2004-10-01

    Large collecting area x-ray telescopes are designed to study the early Universe, trace the evolution of black holes, stars and galaxies, study the chemical evolution of the Universe, and study matter in extreme environments. The Constellation-X mission (Con-X), planned for launch in 2016, will provide ~ 10^4 cm^2 collecting area with 15 arc-sec resolution, with a goal of 5 arc-sec. Future missions require larger collecting area and finer resolution. Generation-X (Gen-X), a NASA Visions Mission, will achieve 100 m^2 effective area at 1 keV and angular resolution of 0.1 arc-sec, half power diameter. We briefly describe the Con-X flowdown of imaging requirements to reflector figure error. To meet requirements beyond Con-X, Gen-X optics will be thinner and more accurately shaped than has ever been accomplished. To meet these challenging goals, we incorporate for the first time active figure control with grazing incidence optics. Piezoelectric material will be deposited in discrete cells directly on the back surface of the optical segments, with the strain directions oriented parallel to the surface. Differential strain between the two layers of the mirror causes localized bending in two directions, enabling local figure control. Adjusting figure on-orbit eases fabrication and metrology. The ability to make changes to mirror figure adds margin by mitigating risk due to launch-induced deformations and/or on-orbit degradation. We flowdown the Gen-X requirements to mirror figure and four telescope designs, and discuss various trades between the designs.

  1. Generation of large-scale forest height and disturbance maps through the fusion of NISAR and GEDI along with TanDEM-X/L

    Science.gov (United States)

    Lei, Y.; Treuhaft, R. N.; Siqueira, P.; Torbick, N.; Lucas, R.; Keller, M. M.; Schmidt, M.; Ducey, M. J.; Salas, W.

    2017-12-01

    Large-scale products of forest height and disturbance are essential for understanding the global carbon distribution as well as its changes in response to natural events and human activities. Regarding this scientific need, both NASA's GEDI and NASA-ISRO's NISAR are going to be launched in the 2018-2021 timeframe in parallel with DLR's current TanDEM-X and/or the proposed TanDEM-L, which provides a lot of potential for global ecosystem mapping. A new simple and efficient method of forest height mapping has been developed for combining spaceborne repeat-pass InSAR and lidar missions (e.g. NISAR and GEDI) which estimates temporal decorrelation parameters of repeat-pass InSAR and uses the lidar data as training samples. An open-access Python-based software has been developed for automated processing. As a result, a mosaic of forest height was generated for US states of Maine and New Hampshire (11.6 million ha) using JAXA's ALOS-1 and ALOS-2 HV-pol InSAR data and a small piece of lidar training samples (44,000 ha) with the height estimates validated against airborne lidar and field inventory data over both flat and mountainous areas. In addition, through estimating and correcting for the temporal decorrelation effects in the spaceborne repeat-pass InSAR coherence data and also utilizing the spaceborne single-pass InSAR phase data, forest disturbance such as selective logging is not only detected but also quantified in subtropical forests of Australia using ALOS-1 HH-pol InSAR data (validated against NASA's Landsat), as well as in tropics of Brazil using TanDEM-X and ALOS-2 HH-pol InSAR data (validated against field inventory data). The operational simplicity and efficiency make these methods a potential observing/processing prototype for the fusion of NISAR, GEDI and TanDEM-X/L.

  2. ASAMPSA2 best-practices guidelines for L2 PSA development and applications. Volume 3 - Extension to Gen IV reactors

    International Nuclear Information System (INIS)

    Bassi, C.; Bonneville, H.; Brinkman, H.; Burgazzi, L.; Polidoro, F.; Vincon, L.; Jouve, S.

    2010-01-01

    The main objective assigned to the Work Package 4 (WP4) of the 'ASAMPSA2' project (EC 7. FPRD) consist in the verification of the potential compliance of L2PSA guidelines based on PWR/BWR reactors (which are specific tasks of WP2 and WP3) with Generation IV representative concepts. Therefore, in order to exhibit potential discrepancies between LWRs and new reactor types, the following work was based on the up-to-date designs of: - The European Fast Reactor (EFR) which will be considered as prototypical of a pool-type Sodium-cooled Fast Reactor (SFR); - The ELSY design for the Lead-cooled Fast Reactor (LFR) technology; - The ANTARES project which could be representative of a Very-High Temperature Reactor (VHTR); - The CEA 2400 MWth Gas-cooled Fast Reactor (GFR). (authors)

  3. Some problems raised by the operation of large nuclear turbo-generator sets. Cooling of shielded conductors. Precautionary steps for their thermal dimensioning

    International Nuclear Information System (INIS)

    Nisol, R.

    1976-01-01

    The role of the shielded conductors as power dissipation feeder from the generator towards the network is recalled. Their natural cooling limits and the possibilities of forced cooling are examined. The known incidence of short-circuit currents upon the components of the generator-network connection is reported [fr

  4. Generative Semantics

    Science.gov (United States)

    Bagha, Karim Nazari

    2011-01-01

    Generative semantics is (or perhaps was) a research program within linguistics, initiated by the work of George Lakoff, John R. Ross, Paul Postal and later McCawley. The approach developed out of transformational generative grammar in the mid 1960s, but stood largely in opposition to work by Noam Chomsky and his students. The nature and genesis of…

  5. FY 1998 Report on development of large-scale wind power generation systems. Research on the future prospects of wind power generation systems; 1998 nendo ogata furyoku hatsuden system kaihatsu. Furyoku hatsuden system no shorai tenbo ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Current status of wind power generation in Japan and situations in foreign countries ahead of Japan are surveyed, in order to clarify the prospects for the future diffusion and expansion of wind power generation systems in Japan. The surveyed trends of wind power generation in Japan include those related to mandatory laws and regulations, e.g., the Electricity Enterprises Act, introductory and operation situations in local autonomies and electric power companies, and R and D efforts by academic and research organizations. The surveyed wind power generation situations in foreign countries include trends of international standardization for wind power generation, and global situations of introducing these systems. The on-the-spot oversea surveys include location/wind conditions in Greece's islands, cyclone-caused damages in India, World Renewable Energy Congress in Perth and advanced technologies in Europe for wind power generation systems, and the survey results are reported in detail. The surveyed R and D projects in Japan include the basic technological R and D plans (draft) for, e.g., wind power generation systems for isolated islands. (NEDO)

  6. CO2 emission reduction potential of large-scale energy efficiency measures in power generation from fossil fuels in China, India, Brazil, Indonesia and South Africa

    OpenAIRE

    Boehme, Benn J.; Krey, Matthias

    2005-01-01

    We quantify the theoretical potential for energy-efficiency CDM projects using best available technology in coal, natural gas or oil fuelled power generation in China, India, Brazil, Indonesia and South Africa, looking at new power plants or retrofit measures. We then discuss the likelihood of the potential emission reductions materialising under CDM. Our results are very sensitive to choices of baseline and project efficiencies and the level of electricity generation from potential emission ...

  7. Tele-operation of the electric power generation and transmission in large complex; Teleoperacao da geracao e transmissao de energia eletrica em complexo de grande porte

    Energy Technology Data Exchange (ETDEWEB)

    Martini, Jose Sidnei Colombo

    1992-07-01

    This work presents the specification and development outstanding aspects of a large supervisory and control power system. The engineering experiment, named SSCH - Hierarchical Supervision and Control System, occurred between 1982 and 1992 at Sao Paulo State and is an industrial automation power system most expressive cases carried out in this decade. More than complex development technical details, important management aspects concerning with large project execution are discussed. The SSCHs special characteristics are its dimension, complexity and realtime network analysis resources, applied to large power systems. (author)

  8. Application of photovoltaic generating system to electric power in large ship; Taiyoko hatsuden system no ogata senpaku eno oyo ni kansuru kento

    Energy Technology Data Exchange (ETDEWEB)

    Katagi, T; Ogawa, S; Nishikawa, E; Hashimoto, T [Kobe University of Mercantile Marine, Kobe (Japan); Ishida, K

    1996-10-27

    This paper describes the design of electric power system in a ship with photovoltaic power generating system, to examine applicability of the photovoltaic power generating system to the inboard power source. It also discusses effectiveness of the system for sea environment. At first, the actual route of a car carrier, meteorological data, and quantity of power consumption were picked up from the deck logbook and engine logbook. Then, the installation area of photovoltaic arrays, the quantity of photovoltaic power generation derived from the quantity of solar radiation, and the capacities of batteries and inverters were calculated, to design the electric power system in the ship with photovoltaic power generation system. Moreover, the NOx and SOx emissions were compared between the present power system and the usual power system using diesel power generator, to discuss the effectiveness of the present system for sea environment. Consequently, it was found that the emission of NOx was reduced by about 33% and the emission of SOx was reduced by about 28% compared to the usual power system. The effectiveness for sea environment was confirmed. 9 refs., 5 figs., 4 tabs.

  9. Data for generation of all Tables and Figures for CTEP publication in 2015 pertaining to large-scale diesel gensets tested

    Data.gov (United States)

    U.S. Environmental Protection Agency — particulate and gaseous emissions and particle optical properties for emissions from large-scale diesel gensets with and without aftermarket PM controls. This...

  10. Large Scale Generation and Characterization of Anti-Human IgA Monoclonal Antibody in Ascitic Fluid of Balb/c Mice

    OpenAIRE

    Fatemeh Ezzatifar; Jafar Majidi; Behzad Baradaran; Leili Aghebati Maleki; Jalal Abdolalizadeh; Mehdi Yousefi

    2015-01-01

    Purpose: Monoclonal antibodies are potentially powerful tools used in biomedical research, diagnosis, and treatment of infectious diseases and cancers. The monoclonal antibody against Human IgA can be used as a diagnostic application to detect infectious diseases. The aim of this study was to improve an appropriate protocol for large-scale production of mAbs against IgA. Methods: For large-scale production of the monoclonal antibody, hybridoma cells that produce monoclonal antibodies again...

  11. Large Scale Generation and Characterization of Anti-Human CD34 Monoclonal Antibody in Ascetic Fluid of Balb/c Mice

    OpenAIRE

    Aghebati Maleki, Leili; Majidi, Jafar; Baradaran, Behzad; Abdolalizadeh, Jalal; Kazemi, Tohid; Aghebati Maleki, Ali; Sineh sepehr, Koushan

    2013-01-01

    Purpose: Monoclonal antibodies or specific antibodies are now an essential tool of biomedical research and are of great commercial and medical value. The purpose of this study was to produce large scale of monoclonal antibody against CD34 in order to diagnostic application in leukemia and purification of human hematopoietic stem/progenitor cells. Methods: For large scale production of monoclonal antibody, hybridoma cells that produce monoclonal antibody against human CD34 were injected into t...

  12. FY 1998 Report on development of large-scale wind power generation systems. Feasibility study on development of new technologies for wind power generation (Study on the development of wind power generation systems for small-scale power grids); 1998 nendo ogata furyoku hatsuden system kaihatsu seika hokokusho. Furyoku hatsuden shingijutsu kaihatsu kanosei chosa (shokibo keito ni okeru furyoku hatsuden system ni kansuru chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This survey includes the characteristics of small-scale power grids, feasibility studies on introduction of wind turbines in these grids, and statuses of application of wind turbines to isolated islands or the like in the advanced countries, in order to promote introduction of wind power generation systems in isolated islands or the like. It is concluded that small-capacity wind power generation systems can be possibly introduced in the intermediate- to large-scale grids in isolated islands, 1,500kW or larger in capacity, in the Tokyo, Kyushu and Okinawa Electric Power Companies' areas. A scheduled steamer ship for isolated islands can carry up to 10 ton track, and introduction of a small-scale wind turbine is more advantageous viewed from the transportation cost. Some foreign countries have the sites which have achieved a high percentage of grid connection of wind power units by stabilizing wind conditions and connecting them to the main high-voltage grids in different manners from those adopted in Japan. For developing wind turbine bodies, most of the foreign countries surveyed are concentrating their efforts on development and manufacture of large-size units, paying little attention on development of small-size wind turbines for isolated islands. For the future prospects, the promising concepts include adoption of wind turbines small in capacity and easy to transport and assemble, and hybrid systems combined with power storage units. (NEDO)

  13. FY 1998 Report on development of large-scale wind power generation systems. Feasibility study on development of new technologies for wind power generation (Study on the development of wind power generation systems for small-scale power grids); 1998 nendo ogata furyoku hatsuden system kaihatsu seika hokokusho. Furyoku hatsuden shingijutsu kaihatsu kanosei chosa (shokibo keito ni okeru furyoku hatsuden system ni kansuru chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This survey includes the characteristics of small-scale power grids, feasibility studies on introduction of wind turbines in these grids, and statuses of application of wind turbines to isolated islands or the like in the advanced countries, in order to promote introduction of wind power generation systems in isolated islands or the like. It is concluded that small-capacity wind power generation systems can be possibly introduced in the intermediate- to large-scale grids in isolated islands, 1,500kW or larger in capacity, in the Tokyo, Kyushu and Okinawa Electric Power Companies' areas. A scheduled steamer ship for isolated islands can carry up to 10 ton track, and introduction of a small-scale wind turbine is more advantageous viewed from the transportation cost. Some foreign countries have the sites which have achieved a high percentage of grid connection of wind power units by stabilizing wind conditions and connecting them to the main high-voltage grids in different manners from those adopted in Japan. For developing wind turbine bodies, most of the foreign countries surveyed are concentrating their efforts on development and manufacture of large-size units, paying little attention on development of small-size wind turbines for isolated islands. For the future prospects, the promising concepts include adoption of wind turbines small in capacity and easy to transport and assemble, and hybrid systems combined with power storage units. (NEDO)

  14. Comparison of runaway electron generation parameters in small, medium-sized and large tokamaks—A survey of experiments in COMPASS, TCV, ASDEX-Upgrade and JET

    Science.gov (United States)

    Plyusnin, V. V.; Reux, C.; Kiptily, V. G.; Pautasso, G.; Decker, J.; Papp, G.; Kallenbach, A.; Weinzettl, V.; Mlynar, J.; Coda, S.; Riccardo, V.; Lomas, P.; Jachmich, S.; Shevelev, A. E.; Alper, B.; Khilkevitch, E.; Martin, Y.; Dux, R.; Fuchs, C.; Duval, B.; Brix, M.; Tardini, G.; Maraschek, M.; Treutterer, W.; Giannone, L.; Mlynek, A.; Ficker, O.; Martin, P.; Gerasimov, S.; Potzel, S.; Paprok, R.; McCarthy, P. J.; Imrisek, M.; Boboc, A.; Lackner, K.; Fernandes, A.; Havlicek, J.; Giacomelli, L.; Vlainic, M.; Nocente, M.; Kruezi, U.; COMPASS Team; TCV Team; ASDEX-Upgrade Team; EUROFusion MST1 Team; contributors, JET

    2018-01-01

    This paper presents a survey of the experiments on runaway electrons (RE) carried out recently in frames of EUROFusion Consortium in different tokamaks: COMPASS, ASDEX-Upgrade, TCV and JET. Massive gas injection (MGI) has been used in different scenarios for RE generation in small and medium-sized tokamaks to elaborate the most efficient and reliable ones for future RE experiments. New data on RE generated at disruptions in COMPASS and ASDEX-Upgrade was collected and added to the JET database. Different accessible parameters of disruptions, such as current quench rate, conversion rate of plasma current into runaways, etc have been analysed for each tokamak and compared to JET data. It was shown, that tokamaks with larger geometrical sizes provide the wider limits for spatial and temporal variation of plasma parameters during disruptions, thus extending the parameter space for RE generation. The second part of experiments was dedicated to study of RE generation in stationary discharges in COMPASS, TCV and JET. Injection of Ne/Ar have been used to mock-up the JET MGI runaway suppression experiments. Secondary RE avalanching was identified and quantified for the first time in the TCV tokamak in RE generating discharges after massive Ne injection. Simulations of the primary RE generation and secondary avalanching dynamics in stationary discharges has demonstrated that RE current fraction created via avalanching could achieve up to 70-75% of the total plasma current in TCV. Relaxations which are reminiscent the phenomena associated to the kinetic instability driven by RE have been detected in RE discharges in TCV. Macroscopic parameters of RE dominating discharges in TCV before and after onset of the instability fit well to the empirical instability criterion, which was established in the early tokamaks and examined by results of recent numerical simulations.

  15. Benefits of coal-fired power generation with flexible CCS in a future northwest European power system with large scale wind power

    NARCIS (Netherlands)

    Van der Wijk, Pieter Cornelis; Brouwer, Anne Sjoerd|info:eu-repo/dai/nl/330822748; Van den Broek, Machteld|info:eu-repo/dai/nl/092946895; Slot, Thijs; Stienstra, Gerard; Van der Veen, Wim; Faaij, André P C

    Coal-fired power generation with carbon capture and storage (CCS) is projected as a cost-effective technology to decarbonize the power sector. Intermittent renewables could reduce its load factor and revenues, so flexible capture unit operation strategies (flexible CCS) have been suggested to

  16. Coordinated Multi-Objective Control of Regulating Resources in Multi-Area Power Systems with Large Penetration of Wind Power Generation

    DEFF Research Database (Denmark)

    Nyeng, Preben; Yang, Bo; Ma, Jian

    2008-01-01

    This paper describes a control algorithm for a Wide Area Energy Storage and Management System (WAEMS). The WAEMS is designed to meet the demand for fast, accurate and reliable regulation services in multi-area power systems with a significant share of wind power and other intermittent generation...

  17. Calculation of alternating current losses in stacks and coils made of second generation high temperature superconducting tapes for large scale applications

    DEFF Research Database (Denmark)

    Zermeno, Victor M. R.; Abrahamsen, Asger Bech; Mijatovic, Nenad

    2013-01-01

    A homogenization method to model a stack of second generation High Temperature Superconducting tapes under AC applied transport current or magnetic field has been obtained. The idea is to find an anisotropic bulk equivalent for the stack such that the geometrical layout of the internal alternatin...

  18. Wind Generators

    Science.gov (United States)

    1989-01-01

    When Enerpro, Inc. president, Frank J. Bourbeau, attempted to file a patent on a system for synchronizing a wind generator to the electric utility grid, he discovered Marshall Space Flight Center's Frank Nola's power factor controller. Bourbeau advanced the technology and received a NASA license and a patent for his Auto Synchronous Controller (ASC). The ASC reduces generator "inrush current," which occurs when large generators are abruptly brought on line. It controls voltage so the generator is smoothly connected to the utility grid when it reaches its synchronous speed, protecting the components from inrush current damage. Generator efficiency is also increased in light winds by applying lower than rated voltage. Wind energy is utilized to drive turbines to generate electricity for utility companies.

  19. Improvement of small-signal stability of power system by controlling doubly fed induction generators of a large-capacity wind farm

    Directory of Open Access Journals (Sweden)

    Tomohiro Adachi

    2016-01-01

    Full Text Available Many wind turbine generations have been installed into power systems around the world, where in recent years doubly fed induction generator (DFIG attracts a lot of attentions because of its efficiency and controllability. However, the DFIG is connected to the power system through inverters and originally does not have an ability to release the kinetic energy of the rotor or resorb the surplus power of the power system as the kinetic energy. Therefore, it has not been made clear how the DFIGs have an influence on small-signal stability in power systems. In this paper, we propose a control scheme of the DFIG and analyse its effect on the small-signal stability of the power system by eigenvalue calculations and time-domain simulations.

  20. Optimal Site Selection of Wind-Solar Complementary Power Generation Project for a Large-Scale Plug-In Charging Station

    Directory of Open Access Journals (Sweden)

    Wenjun Chen

    2017-10-01

    Full Text Available The wind-solar hybrid power generation project combined with electric vehicle charging stations can effectively reduce the impact on the power system caused by the random charging of electric cars, contribute to the in-situ wind-solar complementary system and reduce the harm arising from its output volatility. In this paper, the site selection index system of a landscape complementary power generation project is established by using the statistical methods and statistical analysis in the literature. Subsequently, using the Analytic Network Process to calculate the index weight, a cloud model was used in combination with preference ranking organization method for enrichment evaluations to transform and sort uncertain language information. Finally, using the results of the decision-making for the location of the Shanghai wind-solar complementary project and by carrying out contrast analysis and sensitivity analysis, the superiority and stability of the decision model constructed in this study was demonstrated.

  1. Generation of uniform low-temperature plasma in a pulsed non-self-sustained glow discharge with a large-area hollow cathode

    Energy Technology Data Exchange (ETDEWEB)

    Akhmadeev, Yu. H.; Denisov, V. V., E-mail: volodyadenisov@yandex.ru; Koval, N. N.; Kovalsky, S. S.; Lopatin, I. V.; Schanin, P. M.; Yakovlev, V. V. [Russian Academy of Sciences, Institute of High-Current Electronics, Siberian Branch (Russian Federation)

    2017-01-15

    Generation of plasma in a pulsed non-self-sustained glow discharge with a hollow cathode with an area of ≥2 m{sup 2} at gas pressures of 0.4–1 Pa was studied experimentally. At an auxiliary arc-discharge current of 100 A and a main discharge voltage of 240 V, a pulse-periodic glow discharge with a current amplitude of 370 A, pulse duration of 340 μs, and repetition rate of 1 kHz was obtained. The possibility of creating a uniform gas-discharge plasma with a density of up to 10{sup 12} cm{sup −3} and an electron temperature of 1 eV in a volume of >0.2 m{sup 3} was demonstrated. Such plasma can be efficiently used to treat material surfaces and generate pulsed ion beams with a current density of up to 15 mA/cm{sup 2}.

  2. Clinical relevance of sensitive and quantitative STAT3 mutation analysis using next-generation sequencing in T-cell large granular lymphocytic leukemia

    DEFF Research Database (Denmark)

    Kielsgaard Kristensen, Thomas; Larsen, Martin; Rewes, Annika

    2014-01-01

    Diagnosis of T-cell large granular lymphocytic leukemia (T-LGL) is often challenging because clinical and laboratory characteristics are overlapping with nonneoplastic conditions. Recently, mutation in the STAT3 gene has been identified as a recurrent genetic abnormality in T-LGL. STAT3 mutation...

  3. How to Create a Student-Generated Database, in a Large Nutrition Class, to Illustrate the Analysis of Nutrient and Food Intakes

    Science.gov (United States)

    Gurfinkel, Debbie M.; Wolever, Thomas M. S.

    2017-01-01

    The completion of a 3-d food record, using commonly available nutrient analysis software, is a typical assignment for students in nutrition and food science programs. While these assignments help students evaluate their personal diets, it is insufficient to teach students about surveys of large population cohorts. This paper shows how the Test,…

  4. Generation of 275.4-nm UV output from a large-frame argon-ion laser for fluorescence detection in capillary electrophoresis.

    NARCIS (Netherlands)

    Kok, S.J.; de Ridder, T.; Brinkman, U.A.T.; Velthorst, N.H.; Gooijer, C.; Hoornweg, G.Ph.

    1998-01-01

    A standard, relatively old, large-frame argon-ion laser, which is available in many laboratories, was modified to produce output in the deep- UV (275-306 nm) region by installing a set of inexpensive, commercially available laser mirrors. The deep-UV output is generally applicable as excitation

  5. Next generation semiconductor based-sequencing of a nutrigenetics target gene (GPR120) and association with growth rate in Italian Large White pigs.

    Science.gov (United States)

    Fontanesi, Luca; Bertolini, Francesca; Scotti, Emilio; Schiavo, Giuseppina; Colombo, Michela; Trevisi, Paolo; Ribani, Anisa; Buttazzoni, Luca; Russo, Vincenzo; Dall'Olio, Stefania

    2015-01-01

    The GPR120 gene (also known as FFAR4 or O3FAR1) encodes for a functional omega-3 fatty acid receptor/sensor that mediates potent insulin sensitizing effects by repressing macrophage-induced tissue inflammation. For its functional role, GPR120 could be considered a potential target gene in animal nutrigenetics. In this work we resequenced the porcine GPR120 gene by high throughput Ion Torrent semiconductor sequencing of amplified fragments obtained from 8 DNA pools derived, on the whole, from 153 pigs of different breeds/populations (two Italian Large White pools, Italian Duroc, Italian Landrace, Casertana, Pietrain, Meishan, and wild boars). Three single nucleotide polymorphisms (SNPs), two synonymous substitutions and one in the putative 3'-untranslated region (g.114765469C > T), were identified and their allele frequencies were estimated by sequencing reads count. The g.114765469C > T SNP was also genotyped by PCR-RFLP confirming estimated frequency in Italian Large White pools. Then, this SNP was analyzed in two Italian Large White cohorts using a selective genotyping approach based on extreme and divergent pigs for back fat thickness (BFT) estimated breeding value (EBV) and average daily gain (ADG) EBV. Significant differences of allele and genotype frequencies distribution was observed between the extreme ADG-EBV groups (P < 0.001) whereas this marker was not associated with BFT-EBV.

  6. Doppler method leak detection for LMFBR steam generators. Pt. 2. Detection characteristics of bubble in-water using large scale SG model

    International Nuclear Information System (INIS)

    Kumagai, Hiromichi

    2000-01-01

    To prevent the expansion of tube damage and to maintain structural integrity in the steam generators (SGs) of a fast breeder reactor (FBR), it is necessary to detect precisely and immediately the leakage of water from heat transfer tubes. Therefore, an active acoustic method was developed. Previous studies have revealed that, in practical steam generators, the active acoustic method can detect bubbles of 10 l/s within 10 seconds. However to prevent the expansion of damage to neighboring tubes, it is necessary to detect smaller leakages of water from the heat transfer tubes. The Doppler method is designed to detect small leakages and to find the source of a leak before damage spreads to neighboring tubes. The detection sensitivity of the Doppler method and the influence of background noise were investigated experimentally. In-water experiments were performed using an SG full-sector model that simulates actual SGs. The results show that the Doppler method can detect bubbles of 0.1 l/s (equivalent to a water leak rate of about 0.1 g/s) within a few seconds and that the background noise has little effect on water leak detection performance. The Doppler method thus has great potential for the detection of water leakage in SGs. (author)

  7. The large second-harmonic generation of LiCs{sub 2}PO{sub 4} is caused by the metal-cation-centered groups

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Xiyue; Guo, Guo-Cong; Hong, Maochun; Deng, Shuiquan [State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter (FJIRSM), Chinese Academy of Sciences (CAS), Fuzhou (China); Whangbo, Myung-Hwan [State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter (FJIRSM), Chinese Academy of Sciences (CAS), Fuzhou (China); Department of Chemistry, North Carolina State University, Raleigh, NC (United States)

    2018-04-03

    We evaluated the individual atom contributions to the second harmonic generation (SHG) coefficients of LiCs{sub 2}PO{sub 4} (LCPO) by introducing the partial response functionals on the basis of first principles calculations. The SHG response of LCPO is dominated by the metal-cation-centered groups CsO{sub 6} and LiO{sub 4}, not by the nonmetal-cation-centered groups PO{sub 4} expected from the existing models and theories. The SHG coefficients of LCPO are determined mainly by the occupied orbitals O 2p and Cs 5p as well as by the unoccupied orbitals Cs 5d and Li 2p. For the SHG response of a material, the polarizable atomic orbitals of the occupied and the unoccupied states are both important. (copyright 2018 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

  8. Mid-infrared supercontinuum generation to 12.5μm in large NA chalcogenide step-index fibres pumped at 4.5μm

    DEFF Research Database (Denmark)

    Kubat, Irnis; Agger, Christian; Møller, Uffe Visbech

    2014-01-01

    We present numerical modeling of mid-infrared (MIR) supercontinuum generation (SCG) in dispersion-optimized chalcogenide (CHALC) step-index fibres (SIFs) with exceptionally high numerical aperture (NA) around one, pumped with mode-locked praseodymium-doped (Pr3+) chalcogenide fibre lasers. The 4...... for the highest NA considered but required pumping at 4.7kW as well as up to 3m of fibre to compensate for the lower nonlinearities. The amount of power converted into the 8-10 μm band was 7.5 and 8.8mW for the 8 and 10μm fibres, respectively. For the 20μm core fibres up to 46mW was converted....

  9. Large Scale Generation and Characterization of Anti-Human IgA Monoclonal Antibody in Ascitic Fluid of Balb/c Mice

    Science.gov (United States)

    Ezzatifar, Fatemeh; Majidi, Jafar; Baradaran, Behzad; Aghebati Maleki, Leili; Abdolalizadeh, Jalal; Yousefi, Mehdi

    2015-01-01

    Purpose: Monoclonal antibodies are potentially powerful tools used in biomedical research, diagnosis, and treatment of infectious diseases and cancers. The monoclonal antibody against Human IgA can be used as a diagnostic application to detect infectious diseases. The aim of this study was to improve an appropriate protocol for large-scale production of mAbs against IgA. Methods: For large-scale production of the monoclonal antibody, hybridoma cells that produce monoclonal antibodies against Human IgA were injected intraperitoneally into Balb/c mice that were previously primed with 0.5 ml Pristane. After ten days, ascitic fluid was harvested from the peritoneum of each mouse. The ELISA method was carried out for evaluation of the titration of produced mAbs. The ascitic fluid was investigated in terms of class and subclass by a mouse mAb isotyping kit. MAb was purified from the ascitic fluid by ion exchange chromatography. The purity of the monoclonal antibody was confirmed by SDS-PAGE, and the purified monoclonal antibody was conjugated with HRP. Results: Monoclonal antibodies with high specificity and sensitivity against Human IgA were prepared by hybridoma technology. The subclass of antibody was IgG1 and its light chain was the kappa type. Conclusion: This conjugated monoclonal antibody could have applications in designing ELISA kits in order to diagnose different infectious diseases such as toxoplasmosis and H. Pylori. PMID:25789225

  10. Large Scale Generation and Characterization of Anti-Human IgA Monoclonal Antibody in Ascitic Fluid of Balb/c Mice

    Directory of Open Access Journals (Sweden)

    Fatemeh Ezzatifar

    2015-03-01

    Full Text Available Purpose: Monoclonal antibodies are potentially powerful tools used in biomedical research, diagnosis, and treatment of infectious diseases and cancers. The monoclonal antibody against Human IgA can be used as a diagnostic application to detect infectious diseases. The aim of this study was to improve an appropriate protocol for large-scale production of mAbs against IgA. Methods: For large-scale production of the monoclonal antibody, hybridoma cells that produce monoclonal antibodies against Human IgA were injected intraperitoneally into Balb/c mice that were previously primed with 0.5 ml Pristane. After ten days, ascitic fluid was harvested from the peritoneum of each mouse. The ELISA method was carried out for evaluation of the titration of produced mAbs. The ascitic fluid was investigated in terms of class and subclass by a mouse mAb isotyping kit. MAb was purified from the ascitic fluid by ion exchange chromatography. The purity of the monoclonal antibody was confirmed by SDS-PAGE, and the purified monoclonal antibody was conjugated with HRP. Results: Monoclonal antibodies with high specificity and sensitivity against Human IgA were prepared by hybridoma technology. The subclass of antibody was IgG1 and its light chain was the kappa type. Conclusion: This conjugated monoclonal antibody could have applications in designing ELISA kits in order to diagnose different infectious diseases such as toxoplasmosis and H. Pylori.

  11. Large Scale Generation and Characterization of Anti-Human CD34 Monoclonal Antibody in Ascetic Fluid of Balb/c Mice

    Science.gov (United States)

    Aghebati Maleki, Leili; Majidi, Jafar; Baradaran, Behzad; Abdolalizadeh, Jalal; Kazemi, Tohid; Aghebati Maleki, Ali; Sineh sepehr, Koushan

    2013-01-01

    Purpose: Monoclonal antibodies or specific antibodies are now an essential tool of biomedical research and are of great commercial and medical value. The purpose of this study was to produce large scale of monoclonal antibody against CD34 in order to diagnostic application in leukemia and purification of human hematopoietic stem/progenitor cells. Methods: For large scale production of monoclonal antibody, hybridoma cells that produce monoclonal antibody against human CD34 were injected into the peritoneum of the Balb/c mice which have previously been primed with 0.5 ml Pristane. 5 ml ascitic fluid was harvested from each mouse in two times. Evaluation of mAb titration was assessed by ELISA method. The ascitic fluid was examined for class and subclasses by ELISA mouse mAb isotyping Kit. mAb was purified from ascitic fluid by affinity chromatography on Protein A-Sepharose. Purity of monoclonal antibody was monitored by SDS -PAGE and the purified monoclonal antibody was conjugated with FITC. Results: Monoclonal antibodies with high specificity and sensitivity against human CD34 by hybridoma technology were prepared. The subclass of antibody was IgG1 and its light chain was kappa. Conclusion: The conjugated monoclonal antibody could be a useful tool for isolation, purification and characterization of human hematopoietic stem cells. PMID:24312838

  12. Large Scale Generation and Characterization of Anti-Human CD34 Monoclonal Antibody in Ascetic Fluid of Balb/c Mice

    Directory of Open Access Journals (Sweden)

    Koushan Sineh sepehr

    2013-02-01

    Full Text Available Purpose: Monoclonal antibodies or specific antibodies are now an essential tool of biomedical research and are of great commercial and medical value. The purpose of this study was to produce large scale of monoclonal antibody against CD34 in order to diagnostic application in leukemia and purification of human hematopoietic stem/progenitor cells. Methods: For large scale production of monoclonal antibody, hybridoma cells that produce monoclonal antibody against human CD34 were injected into the peritoneum of the Balb/c mice which have previously been primed with 0.5 ml Pristane. 5 ml ascitic fluid was harvested from each mouse in two times. Evaluation of mAb titration was assessed by ELISA method. The ascitic fluid was examined for class and subclasses by ELISA mouse mAb isotyping Kit. mAb was purified from ascitic fluid by affinity chromatography on Protein A-Sepharose. Purity of monoclonal antibody was monitored by SDS -PAGE and the purified monoclonal antibody was conjugated with FITC. Results: Monoclonal antibodies with high specificity and sensitivity against human CD34 by hybridoma technology were prepared. The subclass of antibody was IgG1 and its light chain was kappa. Conclusion: The conjugated monoclonal antibody could be a useful tool for isolation, purification and characterization of human hematopoietic stem cells.

  13. Next generation non-vacuum, maskless, low temperature nanoparticle ink laser digital direct metal patterning for a large area flexible electronics.

    Directory of Open Access Journals (Sweden)

    Junyeob Yeo

    Full Text Available Flexible electronics opened a new class of future electronics. The foldable, light and durable nature of flexible electronics allows vast flexibility in applications such as display, energy devices and mobile electronics. Even though conventional electronics fabrication methods are well developed for rigid substrates, direct application or slight modification of conventional processes for flexible electronics fabrication cannot work. The future flexible electronics fabrication requires totally new low-temperature process development optimized for flexible substrate and it should be based on new material too. Here we present a simple approach to developing a flexible electronics fabrication without using conventional vacuum deposition and photolithography. We found that direct metal patterning based on laser-induced local melting of metal nanoparticle ink is a promising low-temperature alternative to vacuum deposition- and photolithography-based conventional metal patterning processes. The "digital" nature of the proposed direct metal patterning process removes the need for expensive photomask and allows easy design modification and short turnaround time. This new process can be extremely useful for current small-volume, large-variety manufacturing paradigms. Besides, simple, scalable, fast and low-temperature processes can lead to cost-effective fabrication methods on a large-area polymer substrate. The developed process was successfully applied to demonstrate high-quality Ag patterning (2.1 µΩ·cm and high-performance flexible organic field effect transistor arrays.

  14. Next generation non-vacuum, maskless, low temperature nanoparticle ink laser digital direct metal patterning for a large area flexible electronics.

    Science.gov (United States)

    Yeo, Junyeob; Hong, Sukjoon; Lee, Daehoo; Hotz, Nico; Lee, Ming-Tsang; Grigoropoulos, Costas P; Ko, Seung Hwan

    2012-01-01

    Flexible electronics opened a new class of future electronics. The foldable, light and durable nature of flexible electronics allows vast flexibility in applications such as display, energy devices and mobile electronics. Even though conventional electronics fabrication methods are well developed for rigid substrates, direct application or slight modification of conventional processes for flexible electronics fabrication cannot work. The future flexible electronics fabrication requires totally new low-temperature process development optimized for flexible substrate and it should be based on new material too. Here we present a simple approach to developing a flexible electronics fabrication without using conventional vacuum deposition and photolithography. We found that direct metal patterning based on laser-induced local melting of metal nanoparticle ink is a promising low-temperature alternative to vacuum deposition- and photolithography-based conventional metal patterning processes. The "digital" nature of the proposed direct metal patterning process removes the need for expensive photomask and allows easy design modification and short turnaround time. This new process can be extremely useful for current small-volume, large-variety manufacturing paradigms. Besides, simple, scalable, fast and low-temperature processes can lead to cost-effective fabrication methods on a large-area polymer substrate. The developed process was successfully applied to demonstrate high-quality Ag patterning (2.1 µΩ·cm) and high-performance flexible organic field effect transistor arrays.

  15. Large-area homogeneous periodic surface structures generated on the surface of sputtered boron carbide thin films by femtosecond laser processing

    Energy Technology Data Exchange (ETDEWEB)

    Serra, R., E-mail: ricardo.serra@dem.uc.pt [SEG-CEMUC, Mechanical Engineering Department, University of Coimbra, Rua Luís Reis Santos, 3030-788 Coimbra (Portugal); Oliveira, V. [ICEMS-Instituto de Ciência e Engenharia de Materiais e Superfícies, Avenida Rovisco Pais no 1, 1049-001 Lisbon (Portugal); Instituto Superior de Engenharia de Lisboa, Avenida Conselheiro Emídio Navarro no 1, 1959-007 Lisbon (Portugal); Oliveira, J.C. [SEG-CEMUC, Mechanical Engineering Department, University of Coimbra, Rua Luís Reis Santos, 3030-788 Coimbra (Portugal); Kubart, T. [The Ångström Laboratory, Solid State Electronics, P.O. Box 534, SE-751 21 Uppsala (Sweden); Vilar, R. [Instituto Superior de Engenharia de Lisboa, Avenida Conselheiro Emídio Navarro no 1, 1959-007 Lisbon (Portugal); Instituto Superior Técnico, Avenida Rovisco Pais no 1, 1049-001 Lisbon (Portugal); Cavaleiro, A. [SEG-CEMUC, Mechanical Engineering Department, University of Coimbra, Rua Luís Reis Santos, 3030-788 Coimbra (Portugal)

    2015-03-15

    Highlights: • Large-area LIPSS were formed by femtosecond laser processing B-C films surface. • The LIPSS spatial period increases with laser fluence (140–200 nm). • Stress-related sinusoidal-like undulations were formed on the B-C films surface. • The undulations amplitude (down to a few nanometres) increases with laser fluence. • Laser radiation absorption increases with surface roughness. - Abstract: Amorphous and crystalline sputtered boron carbide thin films have a very high hardness even surpassing that of bulk crystalline boron carbide (≈41 GPa). However, magnetron sputtered B-C films have high friction coefficients (C.o.F) which limit their industrial application. Nanopatterning of materials surfaces has been proposed as a solution to decrease the C.o.F. The contact area of the nanopatterned surfaces is decreased due to the nanometre size of the asperities which results in a significant reduction of adhesion and friction. In the present work, the surface of amorphous and polycrystalline B-C thin films deposited by magnetron sputtering was nanopatterned using infrared femtosecond laser radiation. Successive parallel laser tracks 10 μm apart were overlapped in order to obtain a processed area of about 3 mm{sup 2}. Sinusoidal-like undulations with the same spatial period as the laser tracks were formed on the surface of the amorphous boron carbide films after laser processing. The undulations amplitude increases with increasing laser fluence. The formation of undulations with a 10 μm period was also observed on the surface of the crystalline boron carbide film processed with a pulse energy of 72 μJ. The amplitude of the undulations is about 10 times higher than in the amorphous films processed at the same pulse energy due to the higher roughness of the films and consequent increase in laser radiation absorption. LIPSS formation on the surface of the films was achieved for the three B-C films under study. However, LIPSS are formed under

  16. Large-area homogeneous periodic surface structures generated on the surface of sputtered boron carbide thin films by femtosecond laser processing

    International Nuclear Information System (INIS)

    Serra, R.; Oliveira, V.; Oliveira, J.C.; Kubart, T.; Vilar, R.; Cavaleiro, A.

    2015-01-01

    Highlights: • Large-area LIPSS were formed by femtosecond laser processing B-C films surface. • The LIPSS spatial period increases with laser fluence (140–200 nm). • Stress-related sinusoidal-like undulations were formed on the B-C films surface. • The undulations amplitude (down to a few nanometres) increases with laser fluence. • Laser radiation absorption increases with surface roughness. - Abstract: Amorphous and crystalline sputtered boron carbide thin films have a very high hardness even surpassing that of bulk crystalline boron carbide (≈41 GPa). However, magnetron sputtered B-C films have high friction coefficients (C.o.F) which limit their industrial application. Nanopatterning of materials surfaces has been proposed as a solution to decrease the C.o.F. The contact area of the nanopatterned surfaces is decreased due to the nanometre size of the asperities which results in a significant reduction of adhesion and friction. In the present work, the surface of amorphous and polycrystalline B-C thin films deposited by magnetron sputtering was nanopatterned using infrared femtosecond laser radiation. Successive parallel laser tracks 10 μm apart were overlapped in order to obtain a processed area of about 3 mm 2 . Sinusoidal-like undulations with the same spatial period as the laser tracks were formed on the surface of the amorphous boron carbide films after laser processing. The undulations amplitude increases with increasing laser fluence. The formation of undulations with a 10 μm period was also observed on the surface of the crystalline boron carbide film processed with a pulse energy of 72 μJ. The amplitude of the undulations is about 10 times higher than in the amorphous films processed at the same pulse energy due to the higher roughness of the films and consequent increase in laser radiation absorption. LIPSS formation on the surface of the films was achieved for the three B-C films under study. However, LIPSS are formed under different

  17. Use of second-generation platelet concentrate (platelet-rich fibrin and hydroxyapatite in the management of large periapical inflammatory lesion: A computed tomography scan analysis

    Directory of Open Access Journals (Sweden)

    Hemalatha Hiremath

    2014-01-01

    Full Text Available Periapical surgery is required when periradicular pathosis associated with endodontically treated teeth cannot be resolved by nonsurgical root canal therapy (retreatment, or when retreatment was unsuccessful, not feasible or contraindicated. Endodontic failures can occur when irritants remain within the confines of the root canal, or when an extraradicular infection cannot be eradicated by orthograde root canal treatment. Foreign-body responses toward filling materials, toward cholesterol crystals or radicular cysts, might prevent complete periapical healing. We present here a case report wherein, combination of platelet-rich fibrin (PRF and the hydroxyapatite graft was used to achieve faster healing of the large periapical lesion. Healing was observed within 8 months, which were confirmed by computed tomography, following improved bone density. PRF has many advantages over platelet-rich plasma. It provides a physiologic architecture that is very favorable to the healing process, which is obtained due to the slow polymerization process.

  18. Large Spun Formed Friction-Stir Welded Tank Domes for Liquid Propellant Tanks Made from AA2195: A Technology Demonstration for the Next Generation of Heavy Lift Launchers

    Science.gov (United States)

    Stachulla, M.; Pernpeinter, R.; Brewster J.; Curreri, P.; Hoffman, E.

    2010-01-01

    Improving structural efficiency while reducing manufacturing costs are key objectives when making future heavy-lift launchers more performing and cost efficient. The main enabling technologies are the application of advanced high performance materials as well as cost effective manufacture processes. This paper presents the status and main results of a joint industrial research & development effort to demonstrate TRL 6 of a novel manufacturing process for large liquid propellant tanks for launcher applications. Using high strength aluminium-lithium alloy combined with the spin forming manufacturing technique, this development aims at thinner wall thickness and weight savings up to 25% as well as a significant reduction in manufacturing effort. In this program, the concave spin forming process is used to manufacture tank domes from a single flat plate. Applied to aluminium alloy, this process allows reaching the highest possible material strength status T8, eliminating numerous welding steps which are typically necessary to assemble tank domes from 3D-curved panels. To minimize raw material costs for large diameter tank domes for launchers, the dome blank has been composed from standard plates welded together prior to spin forming by friction stir welding. After welding, the dome blank is contoured in order to meet the required wall thickness distribution. For achieving a material state of T8, also in the welding seams, the applied spin forming process allows the required cold stretching of the 3D-curved dome, with a subsequent ageing in a furnace. This combined manufacturing process has been demonstrated up to TRL 6 for tank domes with a 5.4 m diameter. In this paper, the manufacturing process as well as test results are presented. Plans are shown how this process could be applied to future heavy-lift launch vehicles developments, also for larger dome diameters.

  19. Comparing vector-based and Bayesian memory models using large-scale datasets: User-generated hashtag and tag prediction on Twitter and Stack Overflow.

    Science.gov (United States)

    Stanley, Clayton; Byrne, Michael D

    2016-12-01

    The growth of social media and user-created content on online sites provides unique opportunities to study models of human declarative memory. By framing the task of choosing a hashtag for a tweet and tagging a post on Stack Overflow as a declarative memory retrieval problem, 2 cognitively plausible declarative memory models were applied to millions of posts and tweets and evaluated on how accurately they predict a user's chosen tags. An ACT-R based Bayesian model and a random permutation vector-based model were tested on the large data sets. The results show that past user behavior of tag use is a strong predictor of future behavior. Furthermore, past behavior was successfully incorporated into the random permutation model that previously used only context. Also, ACT-R's attentional weight term was linked to an entropy-weighting natural language processing method used to attenuate high-frequency words (e.g., articles and prepositions). Word order was not found to be a strong predictor of tag use, and the random permutation model performed comparably to the Bayesian model without including word order. This shows that the strength of the random permutation model is not in the ability to represent word order, but rather in the way in which context information is successfully compressed. The results of the large-scale exploration show how the architecture of the 2 memory models can be modified to significantly improve accuracy, and may suggest task-independent general modifications that can help improve model fit to human data in a much wider range of domains. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  20. The relationship between small-scale and large-scale ionospheric electron density irregularities generated by powerful HF electromagnetic waves at high latitudes

    Directory of Open Access Journals (Sweden)

    E. D. Tereshchenko

    2006-11-01

    Full Text Available Satellite radio beacons were used in June 2001 to probe the ionosphere modified by a radio beam produced by the EISCAT high-power, high-frequency (HF transmitter located near Tromsø (Norway. Amplitude scintillations and variations of the phase of 150- and 400-MHz signals from Russian navigational satellites passing over the modified region were observed at three receiver sites. In several papers it has been stressed that in the polar ionosphere the thermal self-focusing on striations during ionospheric modification is the main mechanism resulting in the formation of large-scale (hundreds of meters to kilometers nonlinear structures aligned along the geomagnetic field (magnetic zenith effect. It has also been claimed that the maximum effects caused by small-scale (tens of meters irregularities detected in satellite signals are also observed in the direction parallel to the magnetic field. Contrary to those studies, the present paper shows that the maximum in amplitude scintillations does not correspond strictly to the magnetic zenith direction because high latitude drifts typically cause a considerable anisotropy of small-scale irregularities in a plane perpendicular to the geomagnetic field resulting in a deviation of the amplitude-scintillation peak relative to the minimum angle between the line-of-sight to the satellite and direction of the geomagnetic field lines. The variance of the logarithmic relative amplitude fluctuations is considered here, which is a useful quantity in such studies. The experimental values of the variance are compared with model calculations and good agreement has been found. It is also shown from the experimental data that in most of the satellite passes a variance maximum occurs at a minimum in the phase fluctuations indicating that the artificial excitation of large-scale irregularities is minimum when the excitation of small-scale irregularities is maximum.

  1. MeV and GeV prospects for producing a large ion layer configuration for fusion power generation and breeding

    International Nuclear Information System (INIS)

    McNally, J.R. Jr.

    1983-01-01

    Injection of multi-MeV molecular hydrogen ions into a magnetic mirror or magnetic mirror well can lead to the production of an ion (or proton-E) Layer with prospects for fusion power generation. This involves: (1) slow (exponential or Lorentz) trapping of protons from dissociation and/or ionization of H 2 + ions; (2) electron cyclotron drive of the electronic temperature to reduce the electron stopping power; (3) production of an Ion-Layer, E-Core plasma configuration having prospects for cold fuel feed with in situ axial acceleration of say D 2 + ions into the negative E-Core; (4) ignited advanced fuel burns in the resulting high beta plasma with excess (free) neutrons available for energy multiplication of fissile fuel breeding; (5) development of a nuclear dynamo with fuel feed, plasma energy, and Ion-Layer current maintenance by fusion products; and (6) a natural divertor end loss of ashes with charge separation permitting a natural direct electrical conversion prospect

  2. Assessment of generic solar thermal systems for large power applications: analysis of electric power generating costs for systems larger than 10 MWe

    Energy Technology Data Exchange (ETDEWEB)

    Apley, W.J.; Bird, S.P.; Brown, D.R.; Drost, M.K.; Fort, J.A.; Garrett-Price, B.A.; Patton, W.P.; Williams, T.A.

    1980-11-01

    Seven generic types of collectors, together with associated subsystems for electric power generation, were considered. The collectors can be classified into three categories: (1) two-axis tracking (with compound-curvature reflecting surfaces); (2) one-axis tracking (with single-curvature reflecting surfaces); and (3) nontracking (with low-concentration reflecting surfaces). All seven collectors were analyzed in conceptual system configurations with Rankine-cycle engines. In addition, two of the collectors were analyzed with Brayton-cycle engines, and one was analyzed with a Stirling-cycle engine. With these engine options, and the consideration of both thermal and electrical storage for the Brayton-cycle central receiver, 11 systems were formulated for analysis. Conceptual designs developed for the 11 systems were based on common assumptions of available technology in the 1990 to 2000 time frame. No attempt was made to perform a detailed optimization of each conceptual design. Rather, designs best suited for a comparative evaluation of the concepts were formulated. Costs were estimated on the basis of identical assumptions, ground rules, methodologies, and unit costs of materials and labor applied uniformly to all of the concepts. The computer code SOLSTEP was used to analyze the thermodynamic performance characteristics and energy costs of the 11 concepts. Year-long simulations were performed using meteorological and insolation data for Barstow, California. Results for each concept include levelized energy costs and capacity factors for various combinations of storage capacity and collector field size.

  3. Fine tuning the emission wavelengths of the 7-hydroxy-1-indanone based nano-structure dyes: Near-infrared (NIR) dual emission generation with large stokes shifts

    Science.gov (United States)

    Roohi, Hossein; Alizadeh, Parvaneh

    2018-05-01

    Near-infrared (NIR) fluorescent dyes have recently gained special attention due to their applications to use as molecular probes for imaging of biological targets and sensitive determination. In this study, photophysical properties of the 7-hydroxy-1-indanone based fluorophors A1, A2, A3, B1, B2 and 3R-B2 (R = CF3, NH2, NO2 and OMe) in the gas and three solution phases were probed using TD-DFT method at PBE0/6-311++G(d,p) and M06-2X/6-311++G(d,p) levels of theory. In addition to structural and photophysical properties as well as ESIPT mechanism of all mentioned molecules, the FC and relaxed potential energy surfaces of B2 and 3R-B2 (R = CF3 and NH2) molecules were explored in gas phase and acetonitrile, cyclohexane and water solvents. It is predicted that the A1, A3 and 3R-B2 chromophores afford normal (615-670 nm) and NIR fluorescence emissions (770-940 nm; biological window) with the large Stokes shifts of >160 and >300 nm, respectively. A good aggrement was found between theoretical and experimental results. In sum, these new types of dyes may render the new approaches for the development of the most efficient NIR fluorescent probes for enhanced image contrast and optimal apparent brightness in biological applications.

  4. FY 1998 Report on development of large-scale wind power generation systems. Part 2. Operational research on large-scale wind power generation systems; 1998 nendo ogata furyoku hatsuden system kaihatsu seika hokokusho. 2. Ogata furyoku hatsuden system no unten kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The on-the-spot surveys are conducted and related information is collected for current status of wind power generators connected to power grid systems and simulation techniques therefor in the USA and European countries. In Denmark, the grid system to which wind power generators are connected is a 10kV radiation type system, by which these generators are connected to general consumers. Power quality is investigated by the programs developed by DEFU (Danske Elvarkers Forening Udredning). The German's Norderland Wind Park has the largest capacity in Europe with 35 units of 1.5MW generators. They are connected to a 110kV grind system via ISOREE to control disturbances to the commercial grid system. The USA, used to have the world largest wind power generation capacity, is now plays second fiddle to Germany whose capacity has now exceeded 2,000MW. The country is now seeing the second rush for construction of wind power generators, planning to have a new capacity of 570MW in 1998. Information is also collected from other countries or organizations, including the Netherlands, WREC, Italy and Spain. (NEDO)

  5. FY 1998 Report on development of large-scale wind power generation systems. Part 2. Operational research on large-scale wind power generation systems; 1998 nendo ogata furyoku hatsuden system kaihatsu seika hokokusho. 2. Ogata furyoku hatsuden system no unten kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The on-the-spot surveys are conducted and related information is collected for current status of wind power generators connected to power grid systems and simulation techniques therefor in the USA and European countries. In Denmark, the grid system to which wind power generators are connected is a 10kV radiation type system, by which these generators are connected to general consumers. Power quality is investigated by the programs developed by DEFU (Danske Elvarkers Forening Udredning). The German's Norderland Wind Park has the largest capacity in Europe with 35 units of 1.5MW generators. They are connected to a 110kV grind system via ISOREE to control disturbances to the commercial grid system. The USA, used to have the world largest wind power generation capacity, is now plays second fiddle to Germany whose capacity has now exceeded 2,000MW. The country is now seeing the second rush for construction of wind power generators, planning to have a new capacity of 570MW in 1998. Information is also collected from other countries or organizations, including the Netherlands, WREC, Italy and Spain. (NEDO)

  6. Small changes in Cu redox state and speciation generate large isotope fractionation during adsorption and incorporation of Cu by a phototrophic biofilm

    Science.gov (United States)

    Coutaud, Margot; Méheut, Merlin; Glatzel, Pieter; Pokrovski, Gleb S.; Viers, Jérôme; Rols, Jean-Luc; Pokrovsky, Oleg S.

    2018-01-01

    Despite the importance of phototrophic biofilms in metal cycling in freshwater systems, metal isotope fractionation linked to metal adsorption and uptake by biofilm remains very poorly constrained. Here, copper isotope fractionation by a mature phototrophic biofilm during Cu surface adsorption and incorporation was studied in batch reactor (BR) and open drip flow reactor (DFR) systems at ambient conditions. X-ray Absorption Spectroscopy (both Near Edge Structure, XANES, and Extended Fine Structure, EXAFS) at Cu K-edge of the biofilm after its interaction with Cu in BR experiments allowed characterizing the molecular structure of assimilated Cu and quantifying the degree of CuII to CuI reduction linked to Cu assimilation. For both BR and DFR experiments, Cu adsorption caused enrichment in heavy isotope at the surface of the biofilm relative to the aqueous solution, with an apparent enrichment factor for the adsorption process, ε65Cuads, of +1.1 ± 0.3‰. In contrast, the isotope enrichment factor during copper incorporation into the biofilm (ε65Cuinc) was highly variable, ranging from -0.6 to +0.8‰. This variability of the ε65Cuinc value was likely controlled by Cu cellular uptake via different transport pathways resulting in contrasting fractionation. Specifically, the CuII storage induced enrichment in heavy isotope, whereas the toxicity response of the biofilm to Cu exposure resulted in reduction of CuII to CuI, thus yielding the biofilm enrichment in light isotope. EXAFS analyses suggested that a major part of the Cu assimilated by the biofilm is bound to 5.1 ± 0.3 oxygen or nitrogen atoms, with a small proportion of Cu linked to sulfur atoms (NS biofilm exhibited a similar trend over time of exposure. Our study demonstrates the complexity of biological processes associated with live phototrophic biofilms, which produce large and contrasting isotope fractionations following rather small Cu redox and speciation changes during uptake, storage or release of

  7. Generation of a restriction minus enteropathogenic Escherichia coli E2348/69 strain that is efficiently transformed with large, low copy plasmids

    Directory of Open Access Journals (Sweden)

    Ward Jordan D

    2008-08-01

    Full Text Available Abstract Background Many microbes possess restriction-modification systems that protect them from parasitic DNA molecules. Unfortunately, the presence of a restriction-modification system in a given microbe also hampers genetic analysis. Although plasmids can be successfully conjugated into the enteropathogenic Escherichia coli strain E2348/69 and optimized protocols for competent cell preparation have been developed, we found that a large, low copy (~15 bioluminescent reporter plasmid, pJW15, that we modified for use in EPEC, was exceedingly difficult to transform into E2348/69. We reasoned that a restriction-modification system could be responsible for the low transformation efficiency of E2348/69 and sought to identify and inactivate the responsible gene(s, with the goal of creating an easily transformable strain of EPEC that could complement existing protocols for genetic manipulation of this important pathogen. Results Using bioinformatics, we identified genes in the unfinished enteropathogenic Escherichia coli (EPEC strain E2348/69 genome whose predicted products bear homology to the HsdM methyltransferases, HsdS specificity subunits, and HsdR restriction endonucleases of type I restriction-modification systems. We constructed a strain carrying a deletion of the conserved enzymatic domain of the EPEC HsdR homologue, NH4, and showed that its transformation efficiency was up to four orders of magnitude higher than that of the parent strain. Further, the modification capacity of NH4 remained intact, since plasmids that were normally recalcitrant to transformation into E2348/69 could be transformed upon passage through NH4. NH4 was unaffected in virulence factor production, since bundle forming pilus (BFP subunits and type III secreted (T3S proteins were present at equivalent levels to those seen in E2348/69. Further, NH4 was indistinguishable from E2348/69 in tissue culture infection model assays of localized adherence and T3S. Conclusion We

  8. 3D full-field quantification of cell-induced large deformations in fibrillar biomaterials by combining non-rigid image registration with label-free second harmonic generation.

    Science.gov (United States)

    Jorge-Peñas, Alvaro; Bové, Hannelore; Sanen, Kathleen; Vaeyens, Marie-Mo; Steuwe, Christian; Roeffaers, Maarten; Ameloot, Marcel; Van Oosterwyck, Hans

    2017-08-01

    To advance our current understanding of cell-matrix mechanics and its importance for biomaterials development, advanced three-dimensional (3D) measurement techniques are necessary. Cell-induced deformations of the surrounding matrix are commonly derived from the displacement of embedded fiducial markers, as part of traction force microscopy (TFM) procedures. However, these fluorescent markers may alter the mechanical properties of the matrix or can be taken up by the embedded cells, and therefore influence cellular behavior and fate. In addition, the currently developed methods for calculating cell-induced deformations are generally limited to relatively small deformations, with displacement magnitudes and strains typically of the order of a few microns and less than 10% respectively. Yet, large, complex deformation fields can be expected from cells exerting tractions in fibrillar biomaterials, like collagen. To circumvent these hurdles, we present a technique for the 3D full-field quantification of large cell-generated deformations in collagen, without the need of fiducial markers. We applied non-rigid, Free Form Deformation (FFD)-based image registration to compute full-field displacements induced by MRC-5 human lung fibroblasts in a collagen type I hydrogel by solely relying on second harmonic generation (SHG) from the collagen fibrils. By executing comparative experiments, we show that comparable displacement fields can be derived from both fibrils and fluorescent beads. SHG-based fibril imaging can circumvent all described disadvantages of using fiducial markers. This approach allows measuring 3D full-field deformations under large displacement (of the order of 10 μm) and strain regimes (up to 40%). As such, it holds great promise for the study of large cell-induced deformations as an inherent component of cell-biomaterial interactions and cell-mediated biomaterial remodeling. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Our Roads, A Large Thermoelectric Generator

    Science.gov (United States)

    Weiss, I.

    2017-12-01

    If asphalt can heat up from the solar radiation shining onto it directly, then it will be able to heat water in pipes within the pavement. The heat from the warm water can then be harvested into usable electrical energy, because heat energy can be transformed into electrical energy using the Seebeck Effect. The Seebeck Effect is when a temperature difference causes electrons to move away from the heat, creating an electrical charge. My experiment showed my research-based hypothesis correct. I hypothesized that if asphalt can heat up from the solar radiation shining onto it directly, then it would be able to warm a water system and usable energy could be harvested, because heat energy can be transformed into electrical energy. Asphalt pavement does not reflect the sunlight and hence heats up faster than a light surface that would reflect the sunlight. This means the asphalt absorbs the sunlight and gives off heat, which is wasted energy. By turning heat energy into electricity, cities can provide a source of clean, green energy and reduce their reliance on fossil fuels. The heat given off by asphalt increases the temperature of the air around, contributing to what is known as the urban heat island effect. This heating contributes to the formation of smog and ozone depletion. With the population still growing this would mean increasing city sizes, greater heat island effect and hence an increase in smog and ozone depletion. By harvesting the heat energy in the pavement through my setup, cities can not only create green energy but also reduce the heat radiated from pavement. Converting my system to a neighborhood street would produce higher output. My street measures 800 feet long by 35 feet wide. That gives us 28,000 square feet. At the rate of 5 volts per minute for a 2 square foot area, my street would be able to produce 70,000 volts per minute.

  10. Large Customers (DR Sellers)

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccot, Sila [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-10-25

    State of the large customers for demand response integration of solar and wind into electric grid; openADR; CAISO; DR as a pseudo generation; commercial and industrial DR strategies; California regulations

  11. Cost of power generation. The cost and uncertainties of nuclear power and other CO2-emission reduction techniques for large-scale power generation; Kosten van elektriciteitsopwekking. De kosten en onzekerheden van kernenergie en andere CO2-emissie reducerende technieken voor grootschalige elektriciteitsopwekking

    Energy Technology Data Exchange (ETDEWEB)

    Van Dril, A.W.N. [ECN Beleidsstudies, Petten (Netherlands); Verdonk, M. [Planbureau voor de Leefomgeving PBL, Bilthoven (Netherlands)

    2008-09-15

    In view of recent social and political discussions on nuclear energy, ECN and PBL have gathered and updated information on the cost of options for reducing CO2 emissions in large scale electricity generation. This memo compares the cost of nuclear energy with other large scale options for electricity generation. Special attention is paid to the uncertainties of the cost of nuclear energy. In addition, some external costs and benefits are examined. This memo does not provide a complete framework for comparing the options for generation of electricity, though. Aspects such as public support, various aspects of sustainability and risks are not addressed in this memo. [mk]. [Dutch] Naar aanleiding van de actuele maatschappelijke en politieke discussie over kernenergie hebben ECN en PBL kosteninformatie over opties om CO2-emissies te beperken bij grootschalige opwekking van elektriciteit verzameld en geactualiseerd. In deze notitie worden de kosten van kernenergie vergeleken met andere grootschalige opties van elektriciteitsopwekking. Daarbij wordt speciale aandacht besteed aan de onzekerheden over de kosten van kernenergie. Aanvullend zijn enkele externe kosten en baten beschouwd. Deze notitie geeft echter geen volledig kader om de opties voor de opwekking van elektriciteit met elkaar te vergelijken. Aspecten als draagvlak, diverse duurzaamheidaspecten en risico's zijn in deze notitie namelijk buiten beschouwing gelaten.

  12. Large deviations

    CERN Document Server

    Varadhan, S R S

    2016-01-01

    The theory of large deviations deals with rates at which probabilities of certain events decay as a natural parameter in the problem varies. This book, which is based on a graduate course on large deviations at the Courant Institute, focuses on three concrete sets of examples: (i) diffusions with small noise and the exit problem, (ii) large time behavior of Markov processes and their connection to the Feynman-Kac formula and the related large deviation behavior of the number of distinct sites visited by a random walk, and (iii) interacting particle systems, their scaling limits, and large deviations from their expected limits. For the most part the examples are worked out in detail, and in the process the subject of large deviations is developed. The book will give the reader a flavor of how large deviation theory can help in problems that are not posed directly in terms of large deviations. The reader is assumed to have some familiarity with probability, Markov processes, and interacting particle systems.

  13. The Challenges of Implementing Next Generation Sequencing Across a Large Healthcare System, and the Molecular Epidemiology and Antibiotic Susceptibilities of Carbapenemase-Producing Bacteria in the Healthcare System of the U.S. Department of Defense.

    Directory of Open Access Journals (Sweden)

    Emil Lesho

    Full Text Available We sought to: 1 provide an overview of the genomic epidemiology of an extensive collection of carbapenemase-producing bacteria (CPB collected in the U.S. Department of Defense health system; 2 increase awareness of the public availability of the sequences, isolates, and customized antimicrobial resistance database of that system; and 3 illustrate challenges and offer mitigations for implementing next generation sequencing (NGS across large health systems.Prospective surveillance and system-wide implementation of NGS.288-hospital healthcare network.All phenotypically carbapenem resistant bacteria underwent CarbaNP® testing and PCR, followed by NGS. Commercial (Newbler and Geneious, on-line (ResFinder, and open-source software (Btrim, FLASh, Bowtie2, an Samtools were used for assembly, SNP detection and clustering. Laboratory capacity, throughput, and response time were assessed.From 2009 through 2015, 27,000 multidrug-resistant Gram-negative isolates were submitted. 225 contained carbapenemase-encoding genes (most commonly blaKPC, blaNDM, and blaOXA23. These were found in 15 species from 146 inpatients in 19 facilities. Genetically related CPB were found in more than one hospital. Other clusters or outbreaks were not clonal and involved genetically related plasmids, while some involved several unrelated plasmids. Relatedness depended on the clustering algorithm used. Transmission patterns of plasmids and other mobile genetic elements could not be determined without ultra-long read, single-molecule real-time sequencing. 80% of carbapenem-resistant phenotypes retained susceptibility to aminoglycosides, and 70% retained susceptibility to fluoroquinolones. However, among the CPB-confirmed genotypes, fewer than 25% retained susceptibility to aminoglycosides or fluoroquinolones.Although NGS is increasingly acclaimed to revolutionize clinical practice, resource-constrained environments, large or geographically dispersed healthcare networks, and

  14. The Challenges of Implementing Next Generation Sequencing Across a Large Healthcare System, and the Molecular Epidemiology and Antibiotic Susceptibilities of Carbapenemase-Producing Bacteria in the Healthcare System of the U.S. Department of Defense.

    Science.gov (United States)

    Lesho, Emil; Clifford, Robert; Onmus-Leone, Fatma; Appalla, Lakshmi; Snesrud, Erik; Kwak, Yoon; Ong, Ana; Maybank, Rosslyn; Waterman, Paige; Rohrbeck, Patricia; Julius, Michael; Roth, Amanda; Martinez, Joshua; Nielsen, Lindsey; Steele, Eric; McGann, Patrick; Hinkle, Mary

    2016-01-01

    We sought to: 1) provide an overview of the genomic epidemiology of an extensive collection of carbapenemase-producing bacteria (CPB) collected in the U.S. Department of Defense health system; 2) increase awareness of the public availability of the sequences, isolates, and customized antimicrobial resistance database of that system; and 3) illustrate challenges and offer mitigations for implementing next generation sequencing (NGS) across large health systems. Prospective surveillance and system-wide implementation of NGS. 288-hospital healthcare network. All phenotypically carbapenem resistant bacteria underwent CarbaNP® testing and PCR, followed by NGS. Commercial (Newbler and Geneious), on-line (ResFinder), and open-source software (Btrim, FLASh, Bowtie2, an Samtools) were used for assembly, SNP detection and clustering. Laboratory capacity, throughput, and response time were assessed. From 2009 through 2015, 27,000 multidrug-resistant Gram-negative isolates were submitted. 225 contained carbapenemase-encoding genes (most commonly blaKPC, blaNDM, and blaOXA23). These were found in 15 species from 146 inpatients in 19 facilities. Genetically related CPB were found in more than one hospital. Other clusters or outbreaks were not clonal and involved genetically related plasmids, while some involved several unrelated plasmids. Relatedness depended on the clustering algorithm used. Transmission patterns of plasmids and other mobile genetic elements could not be determined without ultra-long read, single-molecule real-time sequencing. 80% of carbapenem-resistant phenotypes retained susceptibility to aminoglycosides, and 70% retained susceptibility to fluoroquinolones. However, among the CPB-confirmed genotypes, fewer than 25% retained susceptibility to aminoglycosides or fluoroquinolones. Although NGS is increasingly acclaimed to revolutionize clinical practice, resource-constrained environments, large or geographically dispersed healthcare networks, and military or

  15. Methodology for Automatic Generation of Models for Large Urban Spaces Based on GIS Data/Metodología para la generación automática de modelos de grandes espacios urbanos desde información SIG/

    Directory of Open Access Journals (Sweden)

    Sergio Arturo Ordóñez Medina

    2012-12-01

    Full Text Available In the planning and evaluation stages of infrastructure projects, it is necessary to manage huge quantities of information. Cities are very complex systems, which need to be modeled when an intervention is required. Suchmodels allow us to measure the impact of infrastructure changes, simulating hypothetic scenarios and evaluating results. This paper describes a methodology for the automatic generation of urban space models from GIS sources. A Voronoi diagram is used to partition large urban regions and subsequently define zones of interest. Finally, some examples of application models are presented, one used for microsimulation of traffic and another for air pollution simulation.En las etapas de planeación y evaluación de proyectos de infraestructura es necesario manejar grandes cantidades de información. Las ciudades son sistemas complejos que deben ser modeladas para ser intervenidas. Estos modelos permitirón medir el impacto de los cambios de infraestructura, simular escenarios hipotéticos y evaluar resultados. Este artículo describe una metodología para generar automáticamente modelos espaciales urbanos desde fuentes SIG: Un diagrama de Voronoi es usado para dividir grandes regiones urbanas, y a continuación serán definidas las zonas de interés. Finalmente, algunos ejemplos de modelos de aplicación serán presentados, uno usado para microsimulación de tráfico y el otro para simular contaminación atmosférica.

  16. Dynamical downscaling with the fifth-generation Canadian regional climate model (CRCM5) over the CORDEX Arctic domain: effect of large-scale spectral nudging and of empirical correction of sea-surface temperature

    Science.gov (United States)

    Takhsha, Maryam; Nikiéma, Oumarou; Lucas-Picher, Philippe; Laprise, René; Hernández-Díaz, Leticia; Winger, Katja

    2017-10-01

    As part of the CORDEX project, the fifth-generation Canadian Regional Climate Model (CRCM5) is used over the Arctic for climate simulations driven by reanalyses and by the MPI-ESM-MR coupled global climate model (CGCM) under the RCP8.5 scenario. The CRCM5 shows adequate skills capturing general features of mean sea level pressure (MSLP) for all seasons. Evaluating 2-m temperature (T2m) and precipitation is more problematic, because of inconsistencies between observational reference datasets over the Arctic that suffer of a sparse distribution of weather stations. In our study, we additionally investigated the effect of large-scale spectral nudging (SN) on the hindcast simulation driven by reanalyses. The analysis shows that SN is effective in reducing the spring MSLP bias, but otherwise it has little impact. We have also conducted another experiment in which the CGCM-simulated sea-surface temperature (SST) is empirically corrected and used as lower boundary conditions over the ocean for an atmosphere-only global simulation (AGCM), which in turn provides the atmospheric lateral boundary conditions to drive the CRCM5 simulation. This approach, so-called 3-step approach of dynamical downscaling (CGCM-AGCM-RCM), which had considerably improved the CRCM5 historical simulations over Africa, exhibits reduced impact over the Arctic domain. The most notable positive effect over the Arctic is a reduction of the T2m bias over the North Pacific Ocean and the North Atlantic Ocean in all seasons. Future projections using this method are compared with the results obtained with the traditional 2-step dynamical downscaling (CGCM-RCM) to assess the impact of correcting systematic biases of SST upon future-climate projections. The future projections are mostly similar for the two methods, except for precipitation.

  17. Isolation of monocytes from leukapheretic products for large-scale GMP-grade generation of cytomegalovirus-specific T-cell lines by means of an automated elutriation device.

    Science.gov (United States)

    Perseghin, Paolo; D'Amico, Giovanna; Dander, Erica; Gaipa, Giuseppe; Dassi, Maria; Biagi, Ettore; Biondi, Andrea

    2008-08-01

    Dendritic cells (DC) act as antigen-presenting cells in immune response-mediated mechanisms against malignant cells and/or viral or fungal pathogens. CD14+ monocytes have been so far isolated by techniques of plastic adherence or by using immunomagnetic methods. Here the effectiveness of a commercially available cell separation system (Elutra, Gambro BCT) in the separation of monocytes and the large-scale production of cytomegalovirus (CMV)-specific T-cell lines were investigated. Six mononuclear cell (MNC) collections were processed with the Elutra system. Monocyte-enriched fraction was differentiated into DCs by addition of granulocyte-macrophage-colony-stimulating factor and interleukin (IL)-4. After 6 days of culture, DCs were matured in the presence of interferon (IFN)-gamma, IFN-alpha, IL-1beta, tumor necrosis factor-alpha, and poly(I:C) and pulsed with a pool of 48 MHC Class I and II-binding CMV peptides. Lymphocytes were then stimulated with mature autologous CMV peptide-pulsed DCs. After elutriation, the mean monocyte yield was 0.89 x 10(9) +/- 0.65 x 10(9), with a 51.0 +/- 31.6 percent recovery and a 51.1 +/- 35.4 percent purity. A significant correlation was observed when basal monocyte content was related to the postelutriation recovery (p < 0.0116). More than 60 percent of plated monocytes were differentiated into DCs, which after pulsing with CMV peptides, were able to stimulate a robust enrichment in CMV antigen-specific T cells in all tested samples (mean percentage of pentamer-positive CD8+ cells, 35% compared to the initial 2%). Our findings might be helpful for an appropriate MNC collection, to maximize the efficiency of the elutriation system and subsequently obtain an optimal monocyte-enriched yield for further DC generation and T-cell stimulation.

  18. Large-format, high-speed, X-ray pnCCDs combined with electron and ion imaging spectrometers in a multipurpose chamber for experiments at 4th generation light sources

    International Nuclear Information System (INIS)

    Strueder, Lothar; Epp, Sascha; Rolles, Daniel; Hartmann, Robert; Holl, Peter; Lutz, Gerhard; Soltau, Heike; Eckart, Rouven; Reich, Christian; Heinzinger, Klaus; Thamm, Christian; Rudenko, Artem; Krasniqi, Faton; Kuehnel, Kai-Uwe; Bauer, Christian; Schroeter, Claus-Dieter; Moshammer, Robert; Techert, Simone; Miessner, Danilo; Porro, Matteo

    2010-01-01

    Fourth generation accelerator-based light sources, such as VUV and X-ray Free Electron Lasers (FEL), deliver ultra-brilliant (∼10 12 -10 13 photons per bunch) coherent radiation in femtosecond (∼10-100 fs) pulses and, thus, require novel focal plane instrumentation in order to fully exploit their unique capabilities. As an additional challenge for detection devices, existing (FLASH, Hamburg) and future FELs (LCLS, Menlo Park; SCSS, Hyogo and the European XFEL, Hamburg) cover a broad range of photon energies from the EUV to the X-ray regime with significantly different bandwidths and pulse structures reaching up to MHz micro-bunch repetition rates. Moreover, hundreds up to trillions of fragment particles, ions, electrons or scattered photons can emerge when a single light flash impinges on matter with intensities up to 10 22 W/cm 2 . In order to meet these challenges, the Max Planck Advanced Study Group (ASG) within the Center for Free Electron Laser Science (CFEL) has designed the CFEL-ASG MultiPurpose (CAMP) chamber. It is equipped with specially developed photon and charged particle detection devices dedicated to cover large solid-angles. A variety of different targets are supported, such as atomic, (aligned) molecular and cluster jets, particle injectors for bio-samples or fixed target arrangements. CAMP houses 4π solid-angle ion and electron momentum imaging spectrometers ('reaction microscope', REMI, or 'velocity map imaging', VMI) in a unique combination with novel, large-area, broadband (50 eV-25 keV), high-dynamic-range, single-photon-counting and imaging X-ray detectors based on the pnCCDs. This instrumentation allows a new class of coherent diffraction experiments in which both electron and ion emission from the target may be simultaneously monitored. This permits the investigation of dynamic processes in this new regime of ultra-intense, high-energy radiation-matter interaction. After an introduction into the salient features of the CAMP chamber and

  19. Generating Units

    Data.gov (United States)

    Department of Homeland Security — Generating Units are any combination of physically connected generators, reactors, boilers, combustion turbines, and other prime movers operated together to produce...

  20. Large deviations

    CERN Document Server

    Deuschel, Jean-Dominique; Deuschel, Jean-Dominique

    2001-01-01

    This is the second printing of the book first published in 1988. The first four chapters of the volume are based on lectures given by Stroock at MIT in 1987. They form an introduction to the basic ideas of the theory of large deviations and make a suitable package on which to base a semester-length course for advanced graduate students with a strong background in analysis and some probability theory. A large selection of exercises presents important material and many applications. The last two chapters present various non-uniform results (Chapter 5) and outline the analytic approach that allow

  1. Generational diversity.

    Science.gov (United States)

    Kramer, Linda W

    2010-01-01

    Generational diversity has proven challenges for nurse leaders, and generational values may influence ideas about work and career planning. This article discusses generational gaps, influencing factors and support, and the various generational groups present in today's workplace as well as the consequences of need addressing these issues. The article ends with a discussion of possible solutions.

  2. Cheaper power generation from surplus steam generating capacities

    International Nuclear Information System (INIS)

    Gupta, K.

    1996-01-01

    Prior to independence most industries had their own captive power generation. Steam was generated in own medium/low pressure boilers and passed through extraction condensing turbines for power generation. Extraction steam was used for process. With cheaper power made available in Nehru era by undertaking large hydro power schemes, captive power generation in industries was almost abandoned except in sugar and large paper factories, which were high consumers of steam. (author)

  3. Power generation and the environment

    International Nuclear Information System (INIS)

    Robert, L.E.J.; Liss, P.S.; Saunders, P.A.H.

    1990-01-01

    This book reviews environmental aspects of large-scale power generation. It includes historic background of present-generation patterns and a discussion of fossil fuel, nuclear energy, and renewable technologies

  4. Achievement report on contract research. Large-scale project - Results of 1st-phase research and development of MHD power generation system; Plant system no hyoka. Ogata project dai 1 ki MHD hatsuden system kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-03-01

    Described in detail involving the results of component development, assessment, and the indication of problems are the power generation channel, superconductive magnets and a helium refrigeration and liquefaction unit, seeds collector, heat exchanger, combustor, etc. Described involving the result and effect of power generation system research and development and the indication of problems is the research on Mark V and Mark VI operation tests. Described in relation to thermal performance calculation, economic effectiveness calculation, and environmental conservation involving an MHD (magnetohydrodynamic) power plant are the combustion of heavy oil, combustion of natural gas, plant having a 1,000MW power generator as its base load, control of NOx and sulfur in MHD power generation, etc. As for planning for the next stage, the configuration of a 10MW MHD power generation plant, its equipment, construction cost, and preliminary element research, etc., are described. Furthermore, propositions are presented concerning future plans and the prospect of commercial MHD power generators, technological ripple effects due to MHD power generation research and development, and research and development in the future. (NEDO)

  5. Isotope generator

    International Nuclear Information System (INIS)

    1979-01-01

    The patent describes an isotope generator incorporating the possibility of stopping elution before the elution vessel is completely full. Sterile ventilation of the whole system can then occur, including of both generator reservoir and elution vessel. A sterile, and therefore pharmaceutically acceptable, elution fluid is thus obtained and the interior of the generator is not polluted with non-sterile air. (T.P.)

  6. Instant Generation

    Science.gov (United States)

    Loveland, Elaina

    2017-01-01

    Generation Z students (born between 1995-2010) have replaced millennials on college campuses. Generation Z students are entrepreneurial, desire practical skills with their education, and are concerned about the cost of college. This article presents what need to be known about this new generation of students.

  7. Achievement report for fiscal 1976 on research in materials for electrodes and insulation walls. Large-scale technology development (Research and development of magnetohydrodynamic power generation); 1976 nendo denkyoku oyobi zetsuenheki zairyo ni kansuru kenkyu seika

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1977-06-01

    This report covers the achievements attained in fiscal 1976 by the materials working group engaged in the study of materials for electrodes and insulation walls. Fabricated and tested in the study relative to the experimental fabrication of materials for magnetohydrodynamic (MHD) power generation are MgO-Si{sub 3}N{sub 4} based insulation materials, MgO-BN based insulation materials, tin oxide based electrode materials, ZrO{sub 2}-CeO{sub 2} based cold pressed electrode materials, cermet based electrode materials, etc. In the research on basic characteristics and measurement, various electrode materials and insulation wall materials are subjected to a 300-hour K{sub 2}SO{sub 4} corrosion test at 1,300 degrees C. In the simulation of MHD power generation, correlations are investigated between materials, cooling structures, and dynamic characteristics, and data are collected to enable the prediction of performance and consumption of the materials during power generation. A data processing system is developed for the said simulation, and this enhances experimenting efficiency. In the study of insulation wall structures and electrode phenomena, studies are conducted about the thermal stress in power generation duct wall materials, localized anomalous heating due to arc spots, and the transfer of heat between the power generation duct wall materials and the cooling material. (NEDO)

  8. Simple and Realistic Data Generation

    DEFF Research Database (Denmark)

    Pedersen, Kenneth Houkjær; Torp, Kristian; Wind, Rico

    2006-01-01

    This paper presents a generic, DBMS independent, and highly extensible relational data generation tool. The tool can efficiently generate realistic test data for OLTP, OLAP, and data streaming applications. The tool uses a graph model to direct the data generation. This model makes it very simple...... to generate data even for large database schemas with complex inter- and intra table relationships. The model also makes it possible to generate data with very accurate characteristics....

  9. Large ethics.

    Science.gov (United States)

    Chambers, David W

    2008-01-01

    This essay presents an alternative to the traditional view that ethics means judging individual behavior against standards of right and wrong. Instead, ethics is understood as creating ethical communities through the promises we make to each other. The "aim" of ethics is to demonstrate in our own behavior a credible willingness to work to create a mutually better world. The "game" of ethics then becomes searching for strategies that overlap with others' strategies so that we are all better for intending to act on a basis of reciprocal trust. This is a difficult process because we have partial, simultaneous, shifting, and inconsistent views of the world. But despite the reality that we each "frame" ethics in personal terms, it is still possible to create sufficient common understanding to prosper together. Large ethics does not make it a prerequisite for moral behavior that everyone adheres to a universally agreed set of ethical principles; all that is necessary is sufficient overlap in commitment to searching for better alternatives.

  10. Results of the research on electrode and insulation wall material in fiscal 1977. Large scale technological development 'R and D on magneto hydrodynamic generation'; 1977 nendo denkyoku oyobi zetsuenheki zairyo ni kansuru kenkyu seika

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1978-06-01

    Results of research in fiscal 1977 were compiled concerning electrodes and insulation wall materials, the research conducted by the material working group of the magneto hydrodynamic (MHD) generation R and D liaison conference. Researches on trial manufacturing of duct materials for MHD generation were conducted for a Si{sub 3}N{sub 4}-MgO, Si{sub 3}N{sub 4}-Spinel, Spinel and Sialon based insulation wall material, MgO-BN based insulation wall material, tin oxide based electrode material, cold press ZrO{sub 2}-CeO{sub 2} and ZrO{sub 2}-Y{sub 2}O{sub 2} based electrode material, hot press hot hydrostatic pressure ZrO{sub 2}-CeO{sub 2} based electrode material, cermet based electrode material, etc. In the investigation and measurement of basic characteristics, these materials were put through various tests such as 1,300 degree C-300 hr-K{sub 2}SO{sub 4} immersion test, thermal shock resistance, thermal expansibility, oxidation resistance of oxide/nitride based materials. In addition, selection of materials for MHD generation, as well as the examination and degradation analysis of dynamic characteristics, was carried out by simulation of MHD generation, which provided data of various electrodes such as consumption, electrical characteristics (electrode lowering voltage, critical current, etc.) and thermal characteristics (surface temperature, heat flow velocity, etc.) (NEDO)

  11. A viable technology to generate third-generation biofuel

    DEFF Research Database (Denmark)

    Singh, Anoop; Olsen, Stig Irving; Nigam, Poonam Singh

    2011-01-01

    First generation biofuels are commercialized at large as the production technologies are well developed. However, to grow the raw materials, there is a great need to compromise with food security, which made first generation biofuels not so much promising. The second generation of biofuels does...

  12. Querying Large Biological Network Datasets

    Science.gov (United States)

    Gulsoy, Gunhan

    2013-01-01

    New experimental methods has resulted in increasing amount of genetic interaction data to be generated every day. Biological networks are used to store genetic interaction data gathered. Increasing amount of data available requires fast large scale analysis methods. Therefore, we address the problem of querying large biological network datasets.…

  13. Dust devil generation

    International Nuclear Information System (INIS)

    G Onishchenko, O; A Pokhotelov, O; Horton, W; Stenflo, L

    2014-01-01

    The equations describing axi-symmetric nonlinear internal gravity waves in an unstable atmosphere are derived. A hydrodynamic model of a dust devil generation mechanism in such an atmosphere is investigated. It is shown that in an unstably stratified atmosphere the convective plumes with poloidal motion can grow exponentially. Furthermore, it is demonstrated that these convective plumes in an atmosphere with weak large scale toroidal motion are unstable with respect to three-dimensional dust devil generation. (papers)

  14. Health impacts of large dams

    International Nuclear Information System (INIS)

    Lerer, L.B.

    1999-01-01

    Large dams have been criticized because of their negative environmental and social impacts. Public health interest largely has focused on vector-borne diseases, such as schistosomiasis, associated with reservoirs and irrigation projects. Large dams also influence health through changes in water and food security, increases in communicable diseases, and the social disruption caused by construction and involuntary resettlement. Communities living in close proximity to large dams often do not benefit from water transfer and electricity generation revenues. A comprehensive health component is required in environmental and social impact assessments for large dam projects

  15. 大型并网光伏发电系统方案设计探讨%Discussion on the Design of Large-scale Grid-connected Photovoltaic Power Generation System

    Institute of Scientific and Technical Information of China (English)

    马春兰

    2015-01-01

    As a non-exhausted and clean energy source, the solar energy attracts worldwide attention nowadays.A grid-connected photovoltaic power generation project located in the Ruoqiang Industry Park is presented, including the design of photovoltaic power generation system and the optimization scheme, which could be a useful reference for similar pro-jects.%太阳能作为一种永不枯竭、无污染的清洁能源,已经越来越受到科技工作者们的重视,各国也在努力开发和利用太阳能。以若羌产业园区光伏并网项目为依托,介绍了光伏发电站的发电系统方案设计及其优化设计,可供类似工程参考。

  16. Porous La0.6Sr0.4CoO3-δ thin film cathodes for large area micro solid oxide fuel cell power generators

    DEFF Research Database (Denmark)

    Garbayo, A.; Esposito, Vincenzo; Sanna, Simone

    2014-01-01

    Porous La0.6Sr0.4CoO3-δ thin films were fabricated by pulsed laser deposition for being used as a cathode for micro solid oxide fuel cell applications as MEMS power generators. Symmetrical La0.6Sr0.4CoO3-δ/ yttria-stabilized zirconia/La0.6Sr0.4CoO3-δ free-standing membranes were fabricated using ...

  17. Generative Semantics.

    Science.gov (United States)

    King, Margaret

    The first section of this paper deals with the attempts within the framework of transformational grammar to make semantics a systematic part of linguistic description, and outlines the characteristics of the generative semantics position. The second section takes a critical look at generative semantics in its later manifestations, and makes a case…

  18. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2008-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  19. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2010-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  20. Pulse Generator

    Science.gov (United States)

    Greer, Lawrence (Inventor)

    2017-01-01

    An apparatus and a computer-implemented method for generating pulses synchronized to a rising edge of a tachometer signal from rotating machinery are disclosed. For example, in one embodiment, a pulse state machine may be configured to generate a plurality of pulses, and a period state machine may be configured to determine a period for each of the plurality of pulses.

  1. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2007-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  2. Steam generator

    International Nuclear Information System (INIS)

    Fenet, J.-C.

    1980-01-01

    Steam generator particularly intended for use in the coolant system of a pressurized water reactor for vaporizing a secondary liquid, generally water, by the primary cooling liquid of the reactor and comprising special arrangements for drying the steam before it leaves the generator [fr

  3. Superconducting current generators

    International Nuclear Information System (INIS)

    Genevey, P.

    1970-01-01

    After a brief summary of the principle of energy storage and liberation with superconducting coils,two current generators are described that create currents in the range 600 to 1400 A, used for two storage experiments of 25 kJ and 50 kJ respectively. The two current generators are: a) a flux pump and b) a superconducting transformer. Both could be developed into more powerful units. The study shows the advantage of the transformer over the flux pump in order to create large currents. The efficiencies of the two generators are 95 per cent and 40 to 60 per cent respectively. (author) [fr

  4. Large electrostatic accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Jones, C.M.

    1984-01-01

    The increasing importance of energetic heavy ion beams in the study of atomic physics, nuclear physics, and materials science has partially or wholly motivated the construction of a new generation of large electrostatic accelerators designed to operate at terminal potentials of 20 MV or above. In this paper, the author briefly discusses the status of these new accelerators and also discusses several recent technological advances which may be expected to further improve their performance. The paper is divided into four parts: (1) a discussion of the motivation for the construction of large electrostatic accelerators, (2) a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, (3) a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and (4) a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year. Due to time and space constraints, discussion is restricted to consideration of only tandem accelerators.

  5. Large electrostatic accelerators

    International Nuclear Information System (INIS)

    Jones, C.M.

    1984-01-01

    The increasing importance of energetic heavy ion beams in the study of atomic physics, nuclear physics, and materials science has partially or wholly motivated the construction of a new generation of large electrostatic accelerators designed to operate at terminal potentials of 20 MV or above. In this paper, the author briefly discusses the status of these new accelerators and also discusses several recent technological advances which may be expected to further improve their performance. The paper is divided into four parts: (1) a discussion of the motivation for the construction of large electrostatic accelerators, (2) a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, (3) a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and (4) a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year. Due to time and space constraints, discussion is restricted to consideration of only tandem accelerators

  6. Reducing air pollution from electricity-generating large combustion plants in the European Union. An assessment of potential emission reductions of NO{sub X}, SO{sub 2} and dust

    Energy Technology Data Exchange (ETDEWEB)

    Lodewijks, P.; Pieper, H.; Van Wortswinkel, L. [ETC partner Flemish Institute for Technological Research (VITO) (Belgium); Boyce, B.; Adams, M.; Goossens, E. [EEA, Copenhagen (Denmark)

    2013-06-15

    An assessment of potential emission reductions of NO{sub X}, SO{sub 2} and dust - This report presents an assessment of the hypothetical emission reduction potential of NO{sub x}, SO{sub 2} and dust from more than 1 500 of Europe's large combustion plants that operated in 2009. Emissions of these air pollutants could be significantly lower if all plants were to meet the emission limit values as set out in European Union legislation. (Author)

  7. Molten salt reactors and the oil sands: odd couple or key to north american energy independence?

    Energy Technology Data Exchange (ETDEWEB)

    LeBlanc, D., E-mail: d_leblanc@rogers.com [Ottawa Valley Research Associates Ltd., Ottawa, Ontario (Canada); Quesada, M.; Popoff, C.; Way, D. [Penumbra Energy, Calgary, Alberta (Canada)

    2012-07-01

    The use of nuclear power to aid oil sands development has often been proposed largely due to the virtual elimination of natural gas use and thus a large reduction in GHG emissions. Nuclear power can replace natural gas for process steam production (SAGD) and electricity generation but also potentially for hydrogen production to upgrade bitumen for pipeline transit, synthetic crude production and even at the final refinery stage. Prior candidates included CANDU and gas cooled Pebble Bed Reactors. The case for CANDU use can be shown to be marginally economic with a proven technology but with an uncertainty of current construction costs and too large a unit size (~2400 MWth). PBRs offered modest theoretical cost savings, smaller unit size and the ability to offer higher temperatures needed for thermochemical hydrogen production from water. Interest in PBRs however has greatly waned with the cancellation of their major South African development program which highlighted the severe challenges of helium as a coolant and TRISO fuel manufacturing. More recently, Small Modular Reactors based on scaled down light water reactor technology have attracted interest but are unlikely to compete economically outside of niche applications. However, a 'new' reactor option, the Molten Salt Reactor, has been rapidly gaining momentum over the past decade. This 'new' technology was actually developed over 50 years ago as a thorium breeder reactor to compete with the sodium cooled fast breeder reactor (U-Pu cycle). During this time two molten salt test reactors were constructed. A modern version however would likely be a simpler converter design using Low Enriched Uranium but needing only a small fraction the uranium resources of LWRs or CANDUs. Besides resource sustainability, these unique designs offer large potential improvements in the areas of capital costs, safety and nuclear waste. This presentation will explain the unique attributes and advantages of these

  8. FY 1998 Report on development of large-scale wind power generation systems. Research of wind turbines for storm worthy and easy construction; 1998 nendo ogata furyoku hatsuden system kaihatsu. Taikyofu kensetsu yoigata fusha ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The research and development statuses in various countries are surveyed, to have useful information to draw the future R and D directions for wind turbines resistant to storms and easy construction. Greece has sites suitable for wind power generation in mountainous districts, and is developing the systems while taking the characteristic weather conditions into consideration. The country provides information regarding aerodynamic/structural design methods for wind turbine blades applicable to turbulent wind generated by complex terrain, and wind assessment and analyses in complex terrain. In India, on-the-spot surveys are made at the cyclone-attacked wind farms. One of the areas on which the USA is putting emphasis is development of small-size wind turbines and wind-diesel hybrid systems for developing countries and independent grid systems in remote areas. Australia is constructing wind-diesel hybrid systems to be connected to a number of independent grid systems in its western area. In Europe, information is collected for the advanced aerodynamic analysis, construction of offshore wind turbines, and production engineering and facilities for blades and other components from Vestas and N.E.G. Micon as the leading wind turbine makers. (NEDO)

  9. Large Superconducting Magnet Systems

    CERN Document Server

    Védrine, P.

    2014-07-17

    The increase of energy in accelerators over the past decades has led to the design of superconducting magnets for both accelerators and the associated detectors. The use of Nb−Ti superconducting materials allows an increase in the dipole field by up to 10 T compared with the maximum field of 2 T in a conventional magnet. The field bending of the particles in the detectors and generated by the magnets can also be increased. New materials, such as Nb$_{3}$Sn and high temperature superconductor (HTS) conductors, can open the way to higher fields, in the range 13–20 T. The latest generations of fusion machines producing hot plasma also use large superconducting magnet systems.

  10. Large Superconducting Magnet Systems

    Energy Technology Data Exchange (ETDEWEB)

    Védrine, P [Saclay (France)

    2014-07-01

    The increase of energy in accelerators over the past decades has led to the design of superconducting magnets for both accelerators and the associated detectors. The use of Nb−Ti superconducting materials allows an increase in the dipole field by up to 10 T compared with the maximum field of 2 T in a conventional magnet. The field bending of the particles in the detectors and generated by the magnets can also be increased. New materials, such as Nb3Sn and high temperature superconductor (HTS) conductors, can open the way to higher fields, in the range 13–20 T. The latest generations of fusion machines producing hot plasma also use large superconducting magnet systems.

  11. Steam generators - problems and prognosis

    International Nuclear Information System (INIS)

    Tapping, R.L.

    1997-05-01

    Steam-generator problems, largely a consequence of corrosion and fouling, have resulted in increased inspection requirements and more regulatory attention to steam-generator integrity. In addition, utilities have had to develop steam-generator life-management strategies, including cleaning and replacement, to achieve design life. This paper summarizes the pertinent data to 1993/1994, and presents an overview of current steam-generator management practices. (author)

  12. Energy generation

    CSIR Research Space (South Africa)

    Osburn, L

    2009-02-01

    Full Text Available Current perceptions conjure images of photovoltaic panels and wind turbines when green building or sustainable development is discussed. How energy is used and how it is generated are core components of both green building and sustainable...

  13. Radionuclide generators

    International Nuclear Information System (INIS)

    Lambrecht, R.M.; Wollongong Univ.; Tomiyoshi, K.; Sekine, T.

    1997-01-01

    The present status and future directions of research and development on radionuclide generator technology are reported. The recent interest to develop double-neutron capture reactions for production of in vivo generators; neutron rich nuclides for radio-immunotherapeutic pharmaceuticals: and advances with ultra-short lived generators is highlighted. Emphasis is focused on: production of the parent radionuclide; the selection and the evaluation of support materials and eluents with respect to the resultant radiochemical yield of the daughter, and the breakthrough of the radionuclide parent: and, the uses of radionuclide generators in radiopharmaceutical chemistry, biomedical and industrial applications. The 62 Zn → 62 Cu, 66 Ni → 66 Cu, 103m Rh → 103 Rh, 188 W → 188 Re and the 225 Ac → 221 Fr → 213 Bi generators are predicted to be emphasized for future development. Coverage of the 99 Mo → 99m Tc generator was excluded, as it the subject of another review. The literature search ended June, 1996. (orig.)

  14. Large tandem accelerators

    International Nuclear Information System (INIS)

    Jones, C.M.

    1976-01-01

    The increasing importance of energetic heavy ion beams in the study of atomic physics, nuclear physics, and materials science has partially or wholly motivated the construction of a new generation of tandem accelerators designed to operate at maximum terminal potentials in the range 14 to 30 MV. In addition, a number of older tandem accelerators are now being significantly upgraded to improve their heavy ion performance. Both of these developments have reemphasized the importance of negative heavy ion sources. The new large tandem accelerators are described, and the requirements placed on negative heavy ion source technology by these and other tandem accelerators used for the acceleration of heavy ions are discussed. First, a brief description is given of the large tandem accelerators which have been completed recently, are under construction, or are funded for construction, second, the motivation for construction of these accelerators is discussed, and last, criteria for negative ion sources for use with these accelerators are presented

  15. Report on achievements in fiscal 1998. Development of technologies to put photovoltaic power generation systems into practical use - Research and development of solar beam power generation and utilization systems and ancillary technologies (Investigations and researches on large-size energy supply system); 1998 nendo taiyoko hatsuden system jitsuyoka gijutsu kaihatsu seika hokokusho. Taiyoko hatsuden riyo system shuhen gijutsu no kenkyu kaihatsu (ogata energy kyokyu system no chosa kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    With an objective to propose large-size system development scenarios assuming installations in deserts, the following investigations have been carried out: (1) collection of data on societies, economy, and energies in China and other countries where the large systems are assumed to be installed, (2) in order to reduce the costs, comparison was given on power generation cost by using a fixed tracking frame, a single axial tracking frame, and a biaxial tracking frame, (3) in order to evaluate the life cycle, discussions were given on the required energy inputs for system equipment, transmission and transformer equipment, and the installation construction to estimate the energy payback time (EPT) and CO2 emission unit requirement, and (4) discussions on development scenarios. In Item (1), while China expects on natural gas and atomic energy as the supply source, 80% of the energy would be supplied from coal in 2010. The development of new energies in India would further be delayed than in China. In item (2), the trially calculated power generation costs in Mongol by using the fixed frame, single axial tracking frame, and biaxial tracking frame were 8.72, 8.23 and 6.94 yen per watt. In Item (3) The EPT was two years or less in a 100-MW system, and the CO2 emission unit requirements in the silicon systems were 10 to 19 kg-C/kWh. (NEDO)

  16. Radionuclide generators

    International Nuclear Information System (INIS)

    Lambrecht, R.M.

    1983-01-01

    The status of radionuclide generators for chemical research and applications related to the life sciences and biomedical research are reviewed. Emphasis is placed upon convenient, efficient and rapid separation of short-lived daughter radionuclides in a chemical form suitable for use without further chemical manipulation. The focus is on the production of the parent, the radiochemistry associated with processing the parent and daughter, the selection and the characteristic separation methods, and yields. Quality control considerations are briefly noted. The scope of this review includes selected references to applications of radionuclide generators in radiopharmaceutical chemistry, and the life sciences, particularly in diagnostic and therapeutic medicine. The 99 Mo-sup(99m)Tc generator was excluded. 202 references are cited. (orig.)

  17. A large scale analysis of cDNA in Arabidopsis thaliana: generation of 12,028 non-redundant expressed sequence tags from normalized and size-selected cDNA libraries.

    Science.gov (United States)

    Asamizu, E; Nakamura, Y; Sato, S; Tabata, S

    2000-06-30

    For comprehensive analysis of genes expressed in the model dicotyledonous plant, Arabidopsis thaliana, expressed sequence tags (ESTs) were accumulated. Normalized and size-selected cDNA libraries were constructed from aboveground organs, flower buds, roots, green siliques and liquid-cultured seedlings, respectively, and a total of 14,026 5'-end ESTs and 39,207 3'-end ESTs were obtained. The 3'-end ESTs could be clustered into 12,028 non-redundant groups. Similarity search of the non-redundant ESTs against the public non-redundant protein database indicated that 4816 groups show similarity to genes of known function, 1864 to hypothetical genes, and the remaining 5348 are novel sequences. Gene coverage by the non-redundant ESTs was analyzed using the annotated genomic sequences of approximately 10 Mb on chromosomes 3 and 5. A total of 923 regions were hit by at least one EST, among which only 499 regions were hit by the ESTs deposited in the public database. The result indicates that the EST source generated in this project complements the EST data in the public database and facilitates new gene discovery.

  18. Development of large scale wind energy conservation system. Development of control techniques for assembly-type wind power generating systems; Ogata furyoku hatsuden system no kaihatsu. Shugogata furyoku hatsuden system no seigyo gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Takita, M [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for development of control techniques for assembly-type wind power generating systems. The study on optimum system configuration produces 50 to 100kW wind power units for screening small-size wind power plant types, and, at the same time, surveys performance of commercial units and experiences of 9 makers capable of producing the above units. As a result, 3 MICON`s units (output: 100kW, active YAW control, monopole tower, maximum wind speed: 60m/s) are selected. The study on optimum operational techniques integrates 2 medium-size power units into a power line, showing a service factor of 30.2% on the annual average, monthly varying in a range from 11.8 to 45.0%. These units, installed in Miyako Island, were attacked by 3 typhoons of wind velocity of 25m/s or higher in 1994, and the only damage recorded is that of the anemoscope/anemometer. It is found that No.1 unit is located at a better geographical point than the No.2 unit, to produce a higher output. 3 figs., 3 tabs.

  19. Single freeze per vein strategy with the second-generation cryoballoon for atrial fibrillation: a propensity score-matched study between 180- and 240-s application time in a large cohort of patients.

    Science.gov (United States)

    De Regibus, Valentina; Abugattas, Juan-Pablo; Iacopino, Saverio; Mugnai, Giacomo; Storti, Cesare; Conte, Giulio; Auricchio, Angelo; Ströker, Erwin; Coutiño, Hugo-Enrique; Takarada, Ken; Salghetti, Francesca; Lusoc, Ian; Capulzini, Lucio; Brugada, Pedro; de Asmundis, Carlo; Chierchia, Gian-Battista

    2017-11-02

    The single-freeze strategy using the second-generation cryoballoon (CB-A, Arctic Front Advance, Medtronic, Minneapolis, MN, USA) has been reported to be as effective as the recommended double-freeze approach in several single-centre studies. In this retrospective, international, multicentre study, we compare the 3-min single-freeze strategy with the 4-min single-freeze strategy. Four hundred and thirty-two patients having undergone pulmonary vein isolation (PVI) by means of CB-A using a single-freeze strategy were considered for this analysis. A cohort of patients who were treated with a 3-min strategy (Group 1) was compared with a propensity score-matched cohort of patients who underwent a 4-min strategy (Group 2). Pulmonary vein isolation was successfully achieved in all the veins using the 28-mm CB-A. The procedural and fluoroscopy times were lower in Group 1 (67.8 ± 17 vs. 73.8 ± 26.3, P strategies. The procedural and fluoroscopy times were significantly shorter in 3-min per vein strategy. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For Permissions, please email: journals.permissions@oup.com.

  20. Generation and analysis of a large-scale expressed sequence Tag database from a full-length enriched cDNA library of developing leaves of Gossypium hirsutum L.

    Directory of Open Access Journals (Sweden)

    Min Lin

    Full Text Available BACKGROUND: Cotton (Gossypium hirsutum L. is one of the world's most economically-important crops. However, its entire genome has not been sequenced, and limited resources are available in GenBank for understanding the molecular mechanisms underlying leaf development and senescence. METHODOLOGY/PRINCIPAL FINDINGS: In this study, 9,874 high-quality ESTs were generated from a normalized, full-length cDNA library derived from pooled RNA isolated from throughout leaf development during the plant blooming stage. After clustering and assembly of these ESTs, 5,191 unique sequences, representative 1,652 contigs and 3,539 singletons, were obtained. The average unique sequence length was 682 bp. Annotation of these unique sequences revealed that 84.4% showed significant homology to sequences in the NCBI non-redundant protein database, and 57.3% had significant hits to known proteins in the Swiss-Prot database. Comparative analysis indicated that our library added 2,400 ESTs and 991 unique sequences to those known for cotton. The unigenes were functionally characterized by gene ontology annotation. We identified 1,339 and 200 unigenes as potential leaf senescence-related genes and transcription factors, respectively. Moreover, nine genes related to leaf senescence and eleven MYB transcription factors were randomly selected for quantitative real-time PCR (qRT-PCR, which revealed that these genes were regulated differentially during senescence. The qRT-PCR for three GhYLSs revealed that these genes express express preferentially in senescent leaves. CONCLUSIONS/SIGNIFICANCE: These EST resources will provide valuable sequence information for gene expression profiling analyses and functional genomics studies to elucidate their roles, as well as for studying the mechanisms of leaf development and senescence in cotton and discovering candidate genes related to important agronomic traits of cotton. These data will also facilitate future whole-genome sequence

  1. Generation Next

    Science.gov (United States)

    Hawkins, B. Denise

    2010-01-01

    There is a shortage of accounting professors with Ph.D.s who can prepare the next generation. To help reverse the faculty deficit, the American Institute of Certified Public Accountants (CPAs) has created the new Accounting Doctoral Scholars program by pooling more than $17 million and soliciting commitments from more than 70 of the nation's…

  2. Generative Contexts

    Science.gov (United States)

    Lyles, Dan Allen

    Educational research has identified how science, technology, engineering, and mathematics (STEM) practice and education have underperforming metrics in racial and gender diversity, despite decades of intervention. These disparities are part of the construction of a culture of science that is alienating to these populations. Recent studies in a social science framework described as "Generative Justice" have suggested that the context of social and scientific practice might be modified to bring about more just and equitable relations among the disenfranchised by circulating the value they and their non-human allies create back to them in unalienated forms. What is not known are the underlying principles of social and material space that makes a system more or less generative. I employ an autoethnographic method at four sites: a high school science class; a farm committed to "Black and Brown liberation"; a summer program geared towards youth environmental mapping; and a summer workshop for Harlem middle school students. My findings suggest that by identifying instances where material affinity, participatory voice, and creative solidarity are mutually reinforcing, it is possible to create educational contexts that generate unalienated value, and circulate it back to the producers themselves. This cycle of generation may help explain how to create systems of justice that strengthen and grow themselves through successive iterations. The problem of lack of diversity in STEM may be addressed not merely by recruiting the best and the brightest from underrepresented populations, but by changing the context of STEM education to provide tools for its own systematic restructuring.

  3. Steam generators

    International Nuclear Information System (INIS)

    Hayden, R.L.J.

    1979-01-01

    Steam generators for nuclear reactors are designed so that deposition of solids on the surface of the inlet side of the tubesheet or the inlet header with the consequent danger of corrosion and eventual tube failure is obviated or substantially reduced. (U.K.)

  4. Thermoelectric generator

    International Nuclear Information System (INIS)

    Purdy, D.L.

    1978-01-01

    The main components of a thermoelectric generator are housed in an evacuated cylindrical vessel. In the middle of it there is the radioactive heat source, e.g. 90 Sr or 238 Pu, enclosed by a gamma radiation shield. This one is surrounded by a heat-insulating screen from getter material or indicidual sheets of titanium. In the bottom of the screen there are arranged several thermocouples on a circle. The thermocouples themselves are contained within casings sealed gas-tight and filled with an inert gas, e.g. argon. By separating the internal space of the generator vessel from the thermocouple casings, made of e.g. n- respectively p-doped lead telluride cylinders, for both the optimal gas state may be obtained. (DG) [de

  5. Cluster generator

    Science.gov (United States)

    Donchev, Todor I [Urbana, IL; Petrov, Ivan G [Champaign, IL

    2011-05-31

    Described herein is an apparatus and a method for producing atom clusters based on a gas discharge within a hollow cathode. The hollow cathode includes one or more walls. The one or more walls define a sputtering chamber within the hollow cathode and include a material to be sputtered. A hollow anode is positioned at an end of the sputtering chamber, and atom clusters are formed when a gas discharge is generated between the hollow anode and the hollow cathode.

  6. Photon generator

    Science.gov (United States)

    Srinivasan-Rao, Triveni

    2002-01-01

    A photon generator includes an electron gun for emitting an electron beam, a laser for emitting a laser beam, and an interaction ring wherein the laser beam repetitively collides with the electron beam for emitting a high energy photon beam therefrom in the exemplary form of x-rays. The interaction ring is a closed loop, sized and configured for circulating the electron beam with a period substantially equal to the period of the laser beam pulses for effecting repetitive collisions.

  7. Magnetohydrodynamic generation method

    International Nuclear Information System (INIS)

    Masai, Tadahisa; Ishibashi, Eiichi; Kojima, Akihiro.

    1967-01-01

    The present invention relates to a magneto-hydrodynamic generation method which increases the conductivity of active gas and the generated energy. In the conventional method of open-cycle magnetohydrodynamic generation, the working fluid does not possess a favorable electric conductivity since the collision cross section is large when the combustion is carried out in a condition of excess oxygen. Furthermore, combustion under a condition of oxygen shortage is uncapable of completely converting the generated energy. The air preheater or boiler is not sufficient to collect the waste gas resulting in damage and other economic disadvantages. In the present invention, the combustion gas caused by excess fuel in the combuster is supplied to the generator as the working gas, to which air or fully oxidized air is added to be reheated. While incomplete gas used for heat collection is not adequate, the unburned damage may be eliminated by combusting again and increasing the gas temperature and heat collection rate. Furthermore, a diffuser is mounted at the rear side of the generator to decrease the gas combustion rate. Thus, even when directly absorbing the preheated fully oxidized air or the ordinary air, the boiler is free from damage caused by combustion delay or impulsive force. (M. Ishida)

  8. Next generation PWR

    International Nuclear Information System (INIS)

    Tanaka, Toshihiko; Fukuda, Toshihiko; Usui, Shuji

    2001-01-01

    Development of LWR for power generation in Japan has been intended to upgrade its reliability, safety, operability, maintenance and economy as well as to increase its capacity in order, since nuclear power generation for commercial use was begun on 1970, to steadily increase its generation power. And, in Japan, ABWR (advanced BWR) of the most promising LWR in the world, was already used actually and APWR (advanced PWR) with the largest output in the world is also at a step of its actual use. And, development of the APWR in Japan was begun on 1980s, and is at a step of plan on construction of its first machine at early of this century. However, by large change of social affairs, economy of nuclear power generation is extremely required, to be positioned at an APWR improved development reactor promoted by collaboration of five PWR generation companies and the Mitsubishi Electric Co., Ltd. Therefore, on its development, investigation on effect of change in social affairs on nuclear power stations was at first carried out, to establish a design requirement for the next generation PWR. Here were described on outline, reactor core design, safety concept, and safety evaluation of APWR+ and development of an innovative PWR. (G.K.)

  9. Distributed power generation using microturbines

    CSIR Research Space (South Africa)

    Szewczuk, S

    2008-11-01

    Full Text Available At present, the bulk of the world is electricity is generated in central power stations. This approach, one of `economy of size generates electricity in large power stations and delivers it to load centres via an extensive network of transmission...

  10. JET flywheel generators

    International Nuclear Information System (INIS)

    Huart, M.; Sonnerup, L.

    1986-01-01

    Two large vertical shaft flywheel generators each provides the JET device with peak power up to 400 MW and energy up to 2600 MJ per pulse to induce and confine the multi-mega-ampere plasma current. The integrated rotor flywheel consists of a 650 tonne/10 m diameter rim carrying the poles of the machine. The energy is stored kinetically during a 9 min interval of acceleration from half-speed to full-speed and then released during a 20 s long deceleration. A design life of 100 000 cycles at full energy rating was specified. The mechanical design and construction of the generators is reviewed. Particular attention is paid to the assessment of the stresses and fatigue life of the rotor system, its dynamic behaviour (rim movement, critical speed and balancing) and on the performance in operation of the large thrust bearing. (author)

  11. Large reservoirs: Chapter 17

    Science.gov (United States)

    Miranda, Leandro E.; Bettoli, Phillip William

    2010-01-01

    Large impoundments, defined as those with surface area of 200 ha or greater, are relatively new aquatic ecosystems in the global landscape. They represent important economic and environmental resources that provide benefits such as flood control, hydropower generation, navigation, water supply, commercial and recreational fisheries, and various other recreational and esthetic values. Construction of large impoundments was initially driven by economic needs, and ecological consequences received little consideration. However, in recent decades environmental issues have come to the forefront. In the closing decades of the 20th century societal values began to shift, especially in the developed world. Society is no longer willing to accept environmental damage as an inevitable consequence of human development, and it is now recognized that continued environmental degradation is unsustainable. Consequently, construction of large reservoirs has virtually stopped in North America. Nevertheless, in other parts of the world construction of large reservoirs continues. The emergence of systematic reservoir management in the early 20th century was guided by concepts developed for natural lakes (Miranda 1996). However, we now recognize that reservoirs are different and that reservoirs are not independent aquatic systems inasmuch as they are connected to upstream rivers and streams, the downstream river, other reservoirs in the basin, and the watershed. Reservoir systems exhibit longitudinal patterns both within and among reservoirs. Reservoirs are typically arranged sequentially as elements of an interacting network, filter water collected throughout their watersheds, and form a mosaic of predictable patterns. Traditional approaches to fisheries management such as stocking, regulating harvest, and in-lake habitat management do not always produce desired effects in reservoirs. As a result, managers may expend resources with little benefit to either fish or fishing. Some locally

  12. Event generators

    International Nuclear Information System (INIS)

    Durand, D.; Gulminelli, F.; Lopez, O.; Vient, E.

    1998-01-01

    The results concerning the heavy ion collision simulations at Fermi energies by means of phenomenological models obtained in the last two years ar presented. The event generators are essentially following the phase of elaboration of analysis methods of data obtained by INDRA or NAUTILUS 4 π multidetectors. To identify and correctly quantify a phenomenon or a physical quantity it is necessary to verify by simulation the feasibility and validity of the analysis and also to estimate the bias introduced by the experimental filter. Many studies have shown this, for instance: the determination of the collision reaction plan for flow studies, determination of kinematical characteristics of the quasi-projectiles, and the excitation energy measurement stored in the hot nuclei. To Eugene, the currently utilised generator, several improvements were added: introduction of space-time correlations between the different products emitted in the decay of excited nuclei by calculating the trajectories of the particles in the final phase of the reaction; taking into account in the decay cascade of the discrete levels of the lighter fragments; the possibility of the schematically description of the explosion of the nucleus by simultaneous emission of multi-fragments. Thus, by comparing the calculations with the data relative to heavy systems studied with the NAUTILUS assembly it was possible to extract the time scales in the nuclear fragmentation. The utilisation of these event generators was extended to the analysis of INDRA data concerning the determination of the vaporization threshold in the collisions Ar + Ni and also the research of the expansion effects in the collisions Xe + Sn at 50 MeV/u

  13. GENERATIVE LEADERSHIP

    Directory of Open Access Journals (Sweden)

    Janina León

    2010-07-01

    Full Text Available This article presents the results of a research project that studied leadership from the standpoint of the personal conceptions that influence the behavior of local government leaders, as well as those conceptions desired to generate the social transformation processes required in communities. Qualitative methodology was used. Categories of analysis were created based on Pearson’s (1992 model of psychological archetypes. A relevant finding was the limited advance shown by interviewees regarding self-knowledge and a fragmented vision between the observer and the observee, which hinders their ability to take on the challenges that current reality demands from them.

  14. Power generation

    International Nuclear Information System (INIS)

    Nunez, Anibal D.

    2001-01-01

    In the second half of twentieth century, nuclear power became an industrial reality. Now the operating 433 power plants, the 37 plants under construction, near 9000 years/reactor with only one serious accident with emission of radioactive material to the environment (Chernobyl) show the maturity of this technology. Today nuclear power contribute a 17% to the global generation and an increase of 75 % of the demand of electricity is estimated for 2020 while this demand is expected to triplicate by 2050. How this requirement can be satisfied? All the indicators seems to demonstrate that nuclear power will be the solution because of the shortage of other sources, the increase of the prices of the non renewable fuels and the scarce contribution of the renewable ones. In addition, the climatic changes produced by the greenhouse effect make even more attractive nuclear power. The situation of Argentina is analyzed and compared with other countries. The convenience of an increase of nuclear power contribution to the total national generation seems clear and the conclusion of the construction of the Atucha II nuclear power plant is recommended

  15. Variability in large-scale wind power generation

    DEFF Research Database (Denmark)

    Kiviluoma, Juha; Holttinen, Hannele; Weir, David

    2016-01-01

    The paper demonstrates the characteristics of wind power variability and net load variability in multiple power systems based on real data from multiple years. Demonstrated characteristics include probability distribution for different ramp durations, seasonal and diurnal variability and low net ...... with well-dispersed wind power. Copyright © 2015 John Wiley & Sons, Ltd....

  16. Series pid pitch controller of large wind turbines generator

    Directory of Open Access Journals (Sweden)

    Micić Aleksandar D.

    2015-01-01

    Full Text Available For this stable process with oscillatory dynamics, characterized with small damping ratio and dominant transport delay, design of the series PID pitch controller is based on the model obtained from the open-loop process step response, filtered with the second-order Butterworth filter Fbw. Performance of the series PID pitch controller, with the filter Fbw, is analyzed by simulations of the set-point and input/output disturbance responses, including simulations with a colored noise added to the control variable. Excellent performance/robustness tradeoff is obtained, compared to the recently proposed PI pitch controllers and to the modified internal model pitch controller, developed here, which has a natural mechanism to compensate effect of dominant transport delay. [Projekat Ministarstva nauke Republike Srbije, br. III 47016

  17. Ocean currents generate large footprints in marine palaeoclimate proxies

    NARCIS (Netherlands)

    van Sebille, E.; Scussolini, P.; Durgadoo, J.V.; Peeters, F.J.C.; Biastoch, A.; Weijer, W.; Turney, C.; Paris, C.B.; Zahn, R.

    2015-01-01

    Fossils of marine microorganisms such as planktic foraminifera are among the cornerstones of palaeoclimatological studies. It is often assumed that the proxies derived from their shells represent ocean conditions above the location where they were deposited. Planktic foraminifera, however, are

  18. Inflationary susceptibilities, duality and large-scale magnetic fields generation

    CERN Document Server

    Giovannini, Massimo

    2013-01-01

    We investigate what can be said about the interaction of scalar fields with Abelian gauge fields during a quasi-de Sitter phase of expansion and under the assumption that the electric and the magnetic susceptibilities do not coincide. The duality symmetry, transforming the magnetic susceptibility into the inverse of the electric susceptibility, exchanges the magnetic and electric power spectra. The mismatch between the two susceptibilities determines an effective refractive index affecting the evolution of the canonical fields. The constraints imposed by the duration of the inflationary phase and by the magnetogenesis requirements pin down the rate of variation of the susceptibilities that is consistent with the observations of the magnetic field strength over astrophysical and cosmological scales but avoids back-reaction problems. The parameter space of this magnetogenesis scenario is wider than in the case when the susceptibilities are equal, as it happens when the inflaton or some other spectator field is ...

  19. The generation of large networks from web of science data

    NARCIS (Netherlands)

    Leydesdorff, L.; Khan, G.F.; Bornmann, L.

    2014-01-01

    During the 1990s, one of us developed a series of freeware routines (http://www.leydesdorff.net/indicators) that enable the user to organize downloads from the Web of Science (Thomson Reuters) into a relational database, and then to export matrices for further analysis in various formats (for

  20. Plasma generator

    International Nuclear Information System (INIS)

    Omichi, Takeo; Yamanaka, Toshiyuki.

    1976-01-01

    Object: To recycle a coolant in a sealed hollow portion formed interiorly of a plasma limiter itself to thereby to cause direct contact between the coolant and the plasma limiter and increase of contact area therebetween to cool the plasma limiter. Structure: The heat resulting from plasma generated during operation and applied to the body of the plasma limiter is transmitted to the coolant, which recycles through an inlet and outlet pipe, an inlet and outlet nozzle and a hollow portion to hold the plasma limiter at a level less than a predetermined temperature. On the other hand, the heater wire is, at the time of emergency operation, energized to heat the plasma limiter, but this heat is transmitted to the limiter body to increase the temperature thereof. However, the coolant recycling the hollow portion comes into direct contact with the limiter body, and since the plasma limiter surround the hollow portion, the heat amount transmitted from the limiter body to the coolant increases to sufficiently cool the plasma limiter. (Yoshihara, H.)

  1. Utility unbundling : large consumer's perspective

    International Nuclear Information System (INIS)

    Block, C.

    1997-01-01

    The perspectives of Sunoco as a large user of electric power on utility unbundling were presented. Sunoco's Sarnia refinery runs up an energy bill of over $60 million per year for electricity, natural gas (used both as a feedstock as well as a fuel), natural gas liquids and steam. As a large customer Sunoco advocates unbundling of all services, leaving only the 'pipes and wires' as true monopolies. In their view, regulation distorts the market place and prevents the lower prices that would result from competition as has been seen in the airline and telephone industries. Sunoco's expectation is that in the post-deregulated environment large and small consumers will have a choice of energy supplier, and large consumers will increasingly turn to co-generation as the most desirable way of meeting their power needs

  2. Research and development project in fiscal 1990 for large industrial technologies. Achievement report on research and development of ultra-advanced processing systems (Development of high-level processing devices for electric power generation facility members); 1990 nendo chosentan kako system no kenkyu kaihatsu seika hokokusho. Hatsuden shisetsuyo buzai kodo kako sochi kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    Research and development has been performed with an objective to establish the processing technology using excitation beam required for the advanced technology industries, and the ultra-precision machining technology to realize the nano-technology. This paper summarizes the achievements in fiscal 1990. In the research on the large output and long life technology for excimer laser, an average output of 500 W or more was demonstrated achieving the intermediate target by developing and improving the technologies for low electric power gas circulation, high efficiency discharge and excitation, and large output oscillation control. In the research on intensity resistant optical element technology, a prototype device was fabricated to create and process axially symmetrical aspherical shapes, whereas SiC aspherical shape creation and processing were demonstrated at the shape accuracy of three microns or better, and surface roughness of 20 nanometers or less, having achieved the intermediate target. Regarding the large current ion beam, a demonstration device was completed based on improvements and test results on the sheet plasma generator. In the research and development of the high-level processing technology, low-temperature forming technology was developed for oxide ceramic thin films by using the excimer laser abrasion method. (NEDO)

  3. Linear wind generator

    International Nuclear Information System (INIS)

    Kozarov, A.; Petrov, O.; Antonov, J.; Sotirova, S.; Petrova, B.

    2006-01-01

    The purpose of the linear wind-power generator described in this article is to decrease the following disadvantages of the common wind-powered turbine: 1) large bending and twisting moments to the blades and the shaft, especially when strong winds and turbulence exist; 2) significant values of the natural oscillation period of the construction result in the possibility of occurrence of destroying resonance oscillations; 3) high velocity of the peripheral parts of the rotor creating a danger for birds; 4) difficulties, connected with the installation and the operation on the mountain ridges and passages where the wind energy potential is the largest. The working surfaces of the generator in questions driven by the wind are not connected with a joint shaft but each moves along a railway track with few oscillations. So the sizes of each component are small and their number can be rather large. The mechanical trajectory is not a circle but a closed outline in a vertical plain, which consists of two rectilinear sectors, one above the other, connected in their ends by semi-circumferences. The mechanical energy of each component turns into electrical on the principle of the linear electrical generator. A regulation is provided when the direction of the wind is perpendicular to the route. A possibility of effectiveness is shown through aiming of additional quantities of air to the movable components by static barriers

  4. Electrical generator

    International Nuclear Information System (INIS)

    Purdy, D.L.

    1976-01-01

    A nuclear heart pacer having a heat-to-electricity converter including a solid-state thermoelectric unit embedded in rubber which is compressed to impress hydrostatic precompression on the unit is described. The converter and the radioactive heat source are enclosed in a container which includes the electrical circuit components for producing and controlling the pulses; the converter and components being embedded in rubber. The portions of the rubber in the converter and in the container through which heat flows between the radioactive primary source and the hot junction and between the cold junction and the wall of the container are of thermally conducting silicone rubber. The 238 Pu primary radioactive source material is encapsuled in a refractory casing of WC-222 (T-222) which in turn is encapsuled in a corrosion-resistant casing of platinum rhodium, a diffusion barrier separating the WC-222 and the Pt--Rh casings. The Pt--Rh casing is in a closed basket of tantalum. The tantalum protects the Pt--Rh from reacting with other materials during cremation of the host, if any. The casings and basket suppress the transmission of hard x rays generated by the alpha particles from the 238 Pu. The outside casing of the pacer is typically of titanium but its surface is covered by an electrically insulating coating, typically epoxy resin, except over a relatively limited area for effective electrical grounding to the body of the host. It is contemplated that the pacer will be inserted in the host with the exposed titanium engaging a non-muscular region of the body

  5. Semi-Supervised Generation with Cluster-aware Generative Models

    DEFF Research Database (Denmark)

    Maaløe, Lars; Fraccaro, Marco; Winther, Ole

    2017-01-01

    Deep generative models trained with large amounts of unlabelled data have proven to be powerful within the domain of unsupervised learning. Many real life data sets contain a small amount of labelled data points, that are typically disregarded when training generative models. We propose the Clust...... a log-likelihood of −79.38 nats on permutation invariant MNIST, while also achieving competitive semi-supervised classification accuracies. The model can also be trained fully unsupervised, and still improve the log-likelihood performance with respect to related methods.......Deep generative models trained with large amounts of unlabelled data have proven to be powerful within the domain of unsupervised learning. Many real life data sets contain a small amount of labelled data points, that are typically disregarded when training generative models. We propose the Cluster...

  6. Inflow Turbulence Generation Methods

    Science.gov (United States)

    Wu, Xiaohua

    2017-01-01

    Research activities on inflow turbulence generation methods have been vigorous over the past quarter century, accompanying advances in eddy-resolving computations of spatially developing turbulent flows with direct numerical simulation, large-eddy simulation (LES), and hybrid Reynolds-averaged Navier-Stokes-LES. The weak recycling method, rooted in scaling arguments on the canonical incompressible boundary layer, has been applied to supersonic boundary layer, rough surface boundary layer, and microscale urban canopy LES coupled with mesoscale numerical weather forecasting. Synthetic methods, originating from analytical approximation to homogeneous isotropic turbulence, have branched out into several robust methods, including the synthetic random Fourier method, synthetic digital filtering method, synthetic coherent eddy method, and synthetic volume forcing method. This article reviews major progress in inflow turbulence generation methods with an emphasis on fundamental ideas, key milestones, representative applications, and critical issues. Directions for future research in the field are also highlighted.

  7. Magnet Free Generators - 3rd Generation Wind Turbine Generators

    DEFF Research Database (Denmark)

    Jensen, Bogi Bech; Mijatovic, Nenad; Henriksen, Matthew Lee

    2013-01-01

    This paper presents an introduction to superconducting wind turbine generators, which are often referred to as 3rd generation wind turbine generators. Advantages and challenges of superconducting generators are presented with particular focus on possible weight and efficiency improvements. A comp...

  8. The Perceived Work Ethic of K-12 Teachers by Generational Status: Generation X vs. Baby Boom Generation

    Science.gov (United States)

    Petty, Gregory C.

    2013-01-01

    This was an investigation of the work ethic of K-12 educators from Generation X and Baby Boomer generations. Teachers of the baby boom generation were born between 1946 and 1964, and many are beginning to retire. There is an impending teacher shortage due to the large numbers of this group retiring or leaving the profession. School administrators…

  9. Trip generation characteristics of special generators

    Science.gov (United States)

    2010-03-01

    Special generators are introduced in the sequential four-step modeling procedure to represent certain types of facilities whose trip generation characteristics are not fully captured by the standard trip generation module. They are also used in the t...

  10. Computerized Torque Control for Large dc Motors

    Science.gov (United States)

    Willett, Richard M.; Carroll, Michael J.; Geiger, Ronald V.

    1987-01-01

    Speed and torque ranges in generator mode extended. System of shunt resistors, electronic switches, and pulse-width modulation controls torque exerted by large, three-phase, electronically commutated dc motor. Particularly useful for motor operating in generator mode because it extends operating range to low torque and high speed.

  11. Adding large EM stack support

    KAUST Repository

    Holst, Glendon

    2016-12-01

    Serial section electron microscopy (SSEM) image stacks generated using high throughput microscopy techniques are an integral tool for investigating brain connectivity and cell morphology. FIB or 3View scanning electron microscopes easily generate gigabytes of data. In order to produce analyzable 3D dataset from the imaged volumes, efficient and reliable image segmentation is crucial. Classical manual approaches to segmentation are time consuming and labour intensive. Semiautomatic seeded watershed segmentation algorithms, such as those implemented by ilastik image processing software, are a very powerful alternative, substantially speeding up segmentation times. We have used ilastik effectively for small EM stacks – on a laptop, no less; however, ilastik was unable to carve the large EM stacks we needed to segment because its memory requirements grew too large – even for the biggest workstations we had available. For this reason, we refactored the carving module of ilastik to scale it up to large EM stacks on large workstations, and tested its efficiency. We modified the carving module, building on existing blockwise processing functionality to process data in manageable chunks that can fit within RAM (main memory). We review this refactoring work, highlighting the software architecture, design choices, modifications, and issues encountered.

  12. Large aperture optical switching devices

    International Nuclear Information System (INIS)

    Goldhar, J.; Henesian, M.A.

    1983-01-01

    We have developed a new approach to constructing large aperture optical switches for next generation inertial confinement fusion lasers. A transparent plasma electrode formed in low pressure ionized gas acts as a conductive coating to allow the uniform charging of the optical faces of an electro-optic material. In this manner large electric fields can be applied longitudinally to large aperture, high aspect ratio Pockels cells. We propose a four-electrode geometry to create the necessary high conductivity plasma sheets, and have demonstrated fast (less than 10 nsec) switching in a 5x5 cm aperture KD*P Pockels cell with such a design. Detaid modelling of Pockels cell performance with plasma electrodes has been carried out for 15 and 30 cm aperture designs

  13. Large scale structure and baryogenesis

    International Nuclear Information System (INIS)

    Kirilova, D.P.; Chizhov, M.V.

    2001-08-01

    We discuss a possible connection between the large scale structure formation and the baryogenesis in the universe. An update review of the observational indications for the presence of a very large scale 120h -1 Mpc in the distribution of the visible matter of the universe is provided. The possibility to generate a periodic distribution with the characteristic scale 120h -1 Mpc through a mechanism producing quasi-periodic baryon density perturbations during inflationary stage, is discussed. The evolution of the baryon charge density distribution is explored in the framework of a low temperature boson condensate baryogenesis scenario. Both the observed very large scale of a the visible matter distribution in the universe and the observed baryon asymmetry value could naturally appear as a result of the evolution of a complex scalar field condensate, formed at the inflationary stage. Moreover, for some model's parameters a natural separation of matter superclusters from antimatter ones can be achieved. (author)

  14. Power generation in South Africa

    International Nuclear Information System (INIS)

    Van der Walt, N.T.

    1976-01-01

    There have been extensive developments in the power supply industry in South Africa. The most evident of these has been the increase in the size of generating units. Escom has recently placed orders for 600 MW units. In South Africa, with its large indigenous reserves of cheap coal, there was no need to rush into a nuclear power programme before it would be economic and, accordingly the first serious study of nuclear power generation was not undertaken until 1966. A final aspect of power generation which is becoming very important is the control of pollution and protection of the environment

  15. Instantons and Large N

    Science.gov (United States)

    Mariño, Marcos

    2015-09-01

    Preface; Part I. Instantons: 1. Instantons in quantum mechanics; 2. Unstable vacua in quantum field theory; 3. Large order behavior and Borel summability; 4. Non-perturbative aspects of Yang-Mills theories; 5. Instantons and fermions; Part II. Large N: 6. Sigma models at large N; 7. The 1=N expansion in QCD; 8. Matrix models and matrix quantum mechanics at large N; 9. Large N QCD in two dimensions; 10. Instantons at large N; Appendix A. Harmonic analysis on S3; Appendix B. Heat kernel and zeta functions; Appendix C. Effective action for large N sigma models; References; Author index; Subject index.

  16. Steam generator reliability improvement project

    International Nuclear Information System (INIS)

    Blomgren, J.C.; Green, S.J.

    1987-01-01

    Upon successful completion of its research and development technology transfer program, the Electric Power Research Institute's Steam Generator Owners Group (SGOG II) will disband in December 1986 and be replaced in January 1987 by a successor project, the Steam Generator Reliability Project (SGRP). The new project, funded in the EPRI base program, will continue the emphasis on reliability and life extension that was carried forward by SGOG II. The objectives of SGOG II have been met. Causes and remedies have been identified for tubing corrosion problems, such as stress corrosion cracking and pitting, and steam generator technology has been improved in areas such as tube wear prediction and nondestructive evaluation (NDE). These actions have led to improved reliability of steam generators. Now the owners want to continue with a centrally managed program that builds on what has been learned. The goal is to continue to improve steam generator reliability and solve small problems before they become large problems

  17. Steam generator reliability improvement project

    International Nuclear Information System (INIS)

    Blomgren, J.C.; Green, S.J.

    1987-01-01

    Upon successful completion of its research and development technology transfer program, the Electric Power Research Institute's (EPRI's) Steam Generator Owners Group (SGOG II) will disband in December 1986, and be replaced in January 1987, by a successor project, the Steam Generator Reliability Project (SGRP). The new project, funded in the EPRI base program, will continue to emphasize reliability and life extension, which were carried forward by SGOG II. The objectives of SGOG II have been met. Causes and remedies have been identified for tubing corrosion problems such as stress corrosion cracking and pitting, and steam generator technology has been improved in areas such as tube wear prediction and nondestructive evaluation. These actions have led to improved reliability of steam generators. Now the owners want to continue with a centrally managed program that builds on what has been learned. The goal is to continue to improve steam generator reliability and to solve small problems before they become large problems

  18. Self generation, small generation, and embedded generation issues

    International Nuclear Information System (INIS)

    2001-01-01

    The New Brunswick Market Design Committee for electric power restructuring has been directed to examine issues regarding cogeneration and small-scale, on-site generation and how they will fit within the framework of the bilateral contract market. The Committee will also have to deal with issues of generation embedded in a distribution system. The Committee has defined cogeneration as the simultaneous production of electricity and useful thermal energy. Self-generation has been defined as small-scale power generation by an end-user, while embedded generation has been defined as a generation facility that is located within a distribution utility but is not directly connected to the transmission system. The Committee has postponed its decision on whether embedded generation will be eligible to participate under the bilateral contract market for electricity. This report discusses general issues such as the physical support of generation, market support of generation, transition issues and policy issues. It also discusses generation support issues such as operating reserves, transmission tariff issues, and distribution tariffs. Market support issues such as transmission access for generation sales were also considered, along with market access for generation sales, and net metering for behind the meter generation. 7 refs., 1 tab

  19. Electricity generation cost

    International Nuclear Information System (INIS)

    Bald, M.

    1984-01-01

    Also questions of efficiency play a part in the energy discussion. In this context, the economic evaluation of different energy supply variants is of importance. Especially with regard to the generation of electric power there have been discussions again and again during the last years on the advantage of the one or the other kind of electric power generation. In the meantime, a large number of scientific studies has been published on this topic which mainly deal with comparisons of the costs of electric power generated by hard coal or nuclear energy, i.e. of those energy forms which still have the possibilities of expansion. The following part shows a way for the evaluation of efficiency comparisons which starts from simplified assumptions and which works with arithmetical aids, which don't leave the area of the fundamental operations. The general comprehensibility is paid for with cuts on ultimate analytical and arithmetical precision. It will, however, turn out that the results achieved by this method don't differ very much from those which have been won by scientific targets. (orig./UA) [de

  20. The event generator SIMON

    International Nuclear Information System (INIS)

    Durand, D.; Lopez, O.; Nguyen, A.D.

    1997-01-01

    The utilization and development of SIMON generator work was conducted at LPC.This generator was conceived for simple and versatile simulations of different processes occurring in the nuclear collisions at Fermi Energies. At present it is utilized in a large number of French foreign laboratories. Particularly, certain analyses of INDRA data have been done by use of this generator: estimation of collective energy in the Xe + Sn and Gd + U central collisions; shape and space-time correlation analysis in fragment-fragment and particle-fragment output of the same system; calorimetric study of the Xe + Sn and Ar + Ni system; study of the vaporization for the Ar + Ni system. Recently a number of items were improved or modified, among which: the initial configuration was allowed to be non-spherical what permits the analysis of the semi-central collisions; a so-called pre-fragmentation emission may be included to estimate different time constants implied in the fragmentation process

  1. Steam generator life management

    International Nuclear Information System (INIS)

    King, P.; McGillivray, R.; Reinhardt, W.; Millman, J.; King, B.; Schneider, W.

    2003-01-01

    'Full-Text:' Steam Generator Life Management responsibility embodies doing whatever is necessary to maintain the steam generation equipment of a nuclear plant in effective, reliable service. All comes together in that most critical deliverable, namely the submission of the documentation which wins approval for return to service after an outage program. Life management must address all aspects of SG reliability over the life of the plant. Nevertheless, the life management activities leading up to return to service approval is where all of it converges. Steam Generator Life Management activities entail four types of work, all equally important in supporting the objective of successful operation. These activities are i) engineering functions; including identification of inspection and maintenance requirements, outage planning and scope definition plus engineering assessment, design and analysis as necessary to support equipment operation, ii) fitness of service work; including the expert evaluation of degradation mechanisms, disposition of defects for return to service or not, and the fitness for service analysis as required to justify ongoing operation with acceptable defects, iii) inspection work; including large scale eddy current inspection of tubing, the definition of defect size and character, code inspections of pressure vessel integrity and visual inspections for integrity and iv) maintenance work; including repairs, retrofits, cleaning and modifications, all as necessary to implement the measures defined during activities i) through iii). The paper discusses the approach and execution of the program for the achievement of the above objectives and particularly of items i) and ii). (author)

  2. Fabrication experiments for large helix heat exchangers

    International Nuclear Information System (INIS)

    Burgsmueller, P.

    1978-01-01

    The helical tube has gained increasing attention as a heat transfer element for various kinds of heat exchangers over the last decade. Regardless of reactor type and heat transport medium, nuclear steam generators of the helix type are now in operation, installlation, fabrication or in the project phase. As a rule, projects are based on the extrapolation of existing technologies. In the particlular case of steam generators for HTGR power stations, however, existing experience is with steam generators of up to about 2 m diameter whereas several projects involve units more than twice as large. For this reason it was felt that a fabrication experiment was necessary in order to verify the feasibility of modern steam generator designs. A test rig was erected in the SULZER steam generator shops at Mantes, France, and skilled personnel and conventional production tools were employed in conducting experiments relating to the coiling, handling and threading of large helices. (Auth.)

  3. Large Neighborhood Search

    DEFF Research Database (Denmark)

    Pisinger, David; Røpke, Stefan

    2010-01-01

    Heuristics based on large neighborhood search have recently shown outstanding results in solving various transportation and scheduling problems. Large neighborhood search methods explore a complex neighborhood by use of heuristics. Using large neighborhoods makes it possible to find better...... candidate solutions in each iteration and hence traverse a more promising search path. Starting from the large neighborhood search method,we give an overview of very large scale neighborhood search methods and discuss recent variants and extensions like variable depth search and adaptive large neighborhood...

  4. Gearless wind power generator

    Energy Technology Data Exchange (ETDEWEB)

    Soederlund, L.; Ridanpaeae, P.; Vihriaelae, H.; Peraelae, R. [Tampere Univ. of Technology (Finland). Lab. of Electricity and Magnetism

    1998-10-01

    In the project a 100 kW axial flux permanent magnet wind power generator has been designed. The toroidal stator with air gap winding is placed between two rotating discs with permanent magnets. The magnet material is NdBFe due to its excellent magnetic properties compared to other materials. This type of topology enables a very large number of poles compared to conventional machine of the same size. A large number of poles is required to achieve a low rotational speed and consequently a direct driven system. The stator winding is formed by rectangular coils. The end winding is very short leading to small resistive losses. On the other hand, the absence of iron teeth causes eddy current losses in the conductors. These can be restricted to an acceptable level by keeping the wire diameter and flux density small. This means that the number of phases should be large. Several independent three phase systems may be used. The toothless stator also means that the iron losses are small and there exists no cogging torque

  5. Leading Generation Y

    National Research Council Canada - National Science Library

    Newman, Jill M

    2008-01-01

    .... Whether referred to as the Millennial Generation, Generation Y or the Next Generation, the Army needs to consider the gap between Boomers, Generation X and the Soldiers that fill our junior ranks...

  6. Generation of genealogical spin eigenfunctions

    International Nuclear Information System (INIS)

    Grabenstetter, J.E.; Tseng, T.J.; Grein, F.

    1976-01-01

    A method is given for generating the Yamanouchi-Kotani genealogical spin eigenfunctions which requires neither storage of eigenfunctions for smaller numbers of electrons, nor summations of large order, nor explicit use of results from the theory of representations of the symmetric group. An explicit formula is given for the coefficients of expansion in terms of spin products

  7. Large scale electrolysers

    International Nuclear Information System (INIS)

    B Bello; M Junker

    2006-01-01

    Hydrogen production by water electrolysis represents nearly 4 % of the world hydrogen production. Future development of hydrogen vehicles will require large quantities of hydrogen. Installation of large scale hydrogen production plants will be needed. In this context, development of low cost large scale electrolysers that could use 'clean power' seems necessary. ALPHEA HYDROGEN, an European network and center of expertise on hydrogen and fuel cells, has performed for its members a study in 2005 to evaluate the potential of large scale electrolysers to produce hydrogen in the future. The different electrolysis technologies were compared. Then, a state of art of the electrolysis modules currently available was made. A review of the large scale electrolysis plants that have been installed in the world was also realized. The main projects related to large scale electrolysis were also listed. Economy of large scale electrolysers has been discussed. The influence of energy prices on the hydrogen production cost by large scale electrolysis was evaluated. (authors)

  8. Large Pelagics Intercept Survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Large Pelagics Intercept Survey (LPIS) is a dockside survey of private and charterboat captains who have just completed fishing trips directed at large pelagic...

  9. Large electrostatic accelerators

    International Nuclear Information System (INIS)

    Jones, C.M.

    1984-01-01

    The paper is divided into four parts: a discussion of the motivation for the construction of large electrostatic accelerators, a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year

  10. Risk-informed analysis as a support to the preliminary design of the CEA GFR2400

    International Nuclear Information System (INIS)

    Bertrand, F.; Bassi, C.; Azria, P.; Bentivoglio, F.; Messie, A.; Balmain, M.

    2012-01-01

    The integration of safety issues in the early phase of the design of a 4. generation reactor of the concepts is expected. For this purpose, probabilistic insights are increasingly employed in the safety demonstration in combination with the deterministic approach in the frame of a so-called risk informed approach. The present paper deals with the safety assessment of the preliminary design of the GFR2400 developed by CEA and how it has been improved in order to fulfil deterministic criteria as well as to reach a risk level comparable to the generation III reactors. GFR2400 is a 2400 MWth, 3-loops, helium-cooled fast reactor developed at a pre-conceptual design stage whose secondary circuit is filled with a mixture of helium and nitrogen, the ternary circuit being filled with water vaporized in 3 steam generators according to a classical Rankine cycle. The resulting cycle efficiency is very close to 45 %. Considering the results obtained with a preliminary level 1 PSA (L1PSA) model, it emerged that an increased reliability of the DHR (Decay Heat Removal) function in high pressure conditions (not corresponding to a LOCA) was suitable to reduce the overall core damage frequency. On the other hand, some small break LOCA situations were not adequately mitigated according to the line of protection deterministic method. Both issues have been solved by design improvements. In addition, this final L1PSA model, characterized by success criteria based on transient calculations performed with the CATHARE2 code and performed in a perimeter extended to all representative internal initiating events at full operating power, permitted to propose design evolutions that did not increase significantly the CDF. In the same time, those evolutions enabled the DHR system to increase its redundancy level as required in the deterministic approach. Finally, a modified design has been reached implying a more extended covering of various accidental situations by means of a progressive DHR

  11. Great expectations: large wind turbines

    International Nuclear Information System (INIS)

    De Vries, E.

    2001-01-01

    This article focuses on wind turbine product development, and traces the background to wind turbines from the first generation 1.5 MW machines in 1995-6, plans for the second generation 3-5 MW class turbines to meet the expected boom in offshore wind projects, to the anticipated installation of a 4.5 MW turbine, and offshore wind projects planned for 2000-2002. The switch by the market leader Vestas to variable speed operation in 2000, the new product development and marketing strategy taken by the German Pro + Pro consultancy in their design of a 1.5 MW variable speed pitch control concept, the possible limiting of the size of turbines due to logistical difficulties, opportunities offered by air ships for large turbines, and the commissioning of offshore wind farms are discussed. Details of some 2-5 MW offshore wind turbine design specifications are tabulated

  12. Solar thermal aided power generation

    International Nuclear Information System (INIS)

    Hu, Eric; Yang, YongPing; Nishimura, Akira; Yilmaz, Ferdi; Kouzani, Abbas

    2010-01-01

    Fossil fuel based power generation is and will still be the back bone of our world economy, albeit such form of power generation significantly contributes to global CO 2 emissions. Solar energy is a clean, environmental friendly energy source for power generation, however solar photovoltaic electricity generation is not practical for large commercial scales due to its cost and high-tech nature. Solar thermal is another way to use solar energy to generate power. Many attempts to establish solar (solo) thermal power stations have been practiced all over the world. Although there are some advantages in solo solar thermal power systems, the efficiencies and costs of these systems are not so attractive. Alternately by modifying, if possible, the existing coal-fired power stations to generate green sustainable power, a much more efficient means of power generation can be reached. This paper presents the concept of solar aided power generation in conventional coal-fired power stations, i.e., integrating solar (thermal) energy into conventional fossil fuelled power generation cycles (termed as solar aided thermal power). The solar aided power generation (SAPG) concept has technically been derived to use the strong points of the two technologies (traditional regenerative Rankine cycle with relatively higher efficiency and solar heating at relatively low temperature range). The SAPG does not only contribute to increase the efficiencies of the conventional power station and reduce its emission of the greenhouse gases, but also provides a better way to use solar heat to generate the power. This paper presents the advantages of the SAPG at conceptual level.

  13. Environmental effects and large space systems

    Science.gov (United States)

    Garrett, H. B.

    1981-01-01

    When planning large scale operations in space, environmental impact must be considered in addition to radiation, spacecraft charging, contamination, high power and size. Pollution of the atmosphere and space is caused by rocket effluents and by photoelectrons generated by sunlight falling on satellite surfaces even light pollution may result (the SPS may reflect so much light as to be a nuisance to astronomers). Large (100 Km 2) structures also will absorb the high energy particles that impinge on them. Altogether, these effects may drastically alter the Earth's magnetosphere. It is not clear if these alterations will in any way affect the Earth's surface climate. Large structures will also generate large plasma wakes and waves which may cause interference with communications to the vehicle. A high energy, microwave beam from the SPS will cause ionospheric turbulence, affecting UHF and VHF communications. Although none of these effects may ultimately prove critical, they must be considered in the design of large structures.

  14. Large volume cryogenic silicon detectors

    International Nuclear Information System (INIS)

    Braggio, C.; Boscardin, M.; Bressi, G.; Carugno, G.; Corti, D.; Galeazzi, G.; Zorzi, N.

    2009-01-01

    We present preliminary measurements for the development of a large volume silicon detector to detect low energy and low rate energy depositions. The tested detector is a one cm-thick silicon PIN diode with an active volume of 31 cm 3 , cooled to the liquid helium temperature to obtain depletion from thermally-generated free carriers. A thorough study has been done to show that effects of charge trapping during drift disappears at a bias field value of the order of 100V/cm.

  15. Large volume cryogenic silicon detectors

    Energy Technology Data Exchange (ETDEWEB)

    Braggio, C. [Dipartimento di Fisica, Universita di Padova, via Marzolo 8, 35131 Padova (Italy); Boscardin, M. [Fondazione Bruno Kessler (FBK), via Sommarive 18, I-38100 Povo (Italy); Bressi, G. [INFN sez. di Pavia, via Bassi 6, 27100 Pavia (Italy); Carugno, G.; Corti, D. [INFN sez. di Padova, via Marzolo 8, 35131 Padova (Italy); Galeazzi, G. [INFN lab. naz. Legnaro, viale dell' Universita 2, 35020 Legnaro (Italy); Zorzi, N. [Fondazione Bruno Kessler (FBK), via Sommarive 18, I-38100 Povo (Italy)

    2009-12-15

    We present preliminary measurements for the development of a large volume silicon detector to detect low energy and low rate energy depositions. The tested detector is a one cm-thick silicon PIN diode with an active volume of 31 cm{sup 3}, cooled to the liquid helium temperature to obtain depletion from thermally-generated free carriers. A thorough study has been done to show that effects of charge trapping during drift disappears at a bias field value of the order of 100V/cm.

  16. Second harmonic generation microscopy

    DEFF Research Database (Denmark)

    Brüggemann, Dagmar Adeline; Brewer, Jonathan R.; Risbo, Jens

    2010-01-01

    Myofibers and collagen show non-linear optical properties enabling imaging using second harmonic generation (SHG) microscopy. The technique is evaluated for use as a tool for real-time studies of thermally induced changes in thin samples of unfixed and unstained pork. The forward and the backward...... scattered SHG light reveal complementary features of the structures of myofibers and collagen fibers. Upon heating the myofibers show no structural changes before reaching a temperature of 53 °C. At this temperature the SHG signal becomes extinct. The extinction of the SHG at 53 °C coincides with a low......-temperature endotherm peak observable in the differential scanning calorimetry (DSC) thermograms. DSC analysis of epimysium, the connective tissue layer that enfold skeletal muscles, produces one large endotherm starting at 57 °C and peaking at 59.5 °C. SHG microscopy of collagen fibers reveals a variability of thermal...

  17. Steam generator tube performance

    International Nuclear Information System (INIS)

    Tatone, O.S.; Pathania, R.S.

    1983-08-01

    A review of the performance of steam generator tubes in 110 water-cooled nuclear power reactors showed that tubes were plugged at 46 (42 percent) of the reactors. The number of tubes removed from service increased from 1900 (0.14 percent) in 1980 to 4692 (0.30 percent) in 1981. The leading causes of tube failures were stress corrosion cracking from the primary side, stress corrosion cracking (or intergranular attack) from the secondary side and pitting corrosion. The lowest incidence of corrosion-induced defects from the secondary side occurred in reactors that used all-volatile treatment since start-up. At one reactor a large number of degraded tubes were repaired by sleeving which is expected to become an important method of tube repair in the future

  18. A Clustering Graph Generator

    Energy Technology Data Exchange (ETDEWEB)

    Winlaw, Manda [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); De Sterck, Hans [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sanders, Geoffrey [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-26

    In very simple terms a network can be de ned as a collection of points joined together by lines. Thus, networks can be used to represent connections between entities in a wide variety of elds including engi- neering, science, medicine, and sociology. Many large real-world networks share a surprising number of properties, leading to a strong interest in model development research and techniques for building synthetic networks have been developed, that capture these similarities and replicate real-world graphs. Modeling these real-world networks serves two purposes. First, building models that mimic the patterns and prop- erties of real networks helps to understand the implications of these patterns and helps determine which patterns are important. If we develop a generative process to synthesize real networks we can also examine which growth processes are plausible and which are not. Secondly, high-quality, large-scale network data is often not available, because of economic, legal, technological, or other obstacles [7]. Thus, there are many instances where the systems of interest cannot be represented by a single exemplar network. As one example, consider the eld of cybersecurity, where systems require testing across diverse threat scenarios and validation across diverse network structures. In these cases, where there is no single exemplar network, the systems must instead be modeled as a collection of networks in which the variation among them may be just as important as their common features. By developing processes to build synthetic models, so-called graph generators, we can build synthetic networks that capture both the essential features of a system and realistic variability. Then we can use such synthetic graphs to perform tasks such as simulations, analysis, and decision making. We can also use synthetic graphs to performance test graph analysis algorithms, including clustering algorithms and anomaly detection algorithms.

  19. Next generation toroidal devices

    International Nuclear Information System (INIS)

    Yoshikawa, Shoichi

    1998-10-01

    A general survey of the possible approach for the next generation toroidal devices was made. Either surprisingly or obviously (depending on one's view), the technical constraints along with the scientific considerations lead to a fairly limited set of systems for the most favorable approach for the next generation devices. Specifically if the magnetic field strength of 5 T or above is to be created by superconducting coils, it imposes minimum in the aspect ratio for the tokamak which is slightly higher than contemplated now for ITER design. The similar technical constraints make the minimum linear size of a stellarator large. Scientifically, it is indicated that a tokamak of 1.5 times in the linear dimension should be able to produce economically, especially if a hybrid reactor is allowed. For the next stellarator, it is strongly suggested that some kind of helical axis is necessary both for the (almost) absolute confinement of high energy particles and high stability and equilibrium beta limits. The author still favors a heliac most. Although it may not have been clearly stated in the main text, the stability afforded by the shearless layer may be exploited fully in a stellarator. (author)

  20. Next generation toroidal devices

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, Shoichi [Princeton Plasma Physics Lab., Princeton Univ., NJ (United States)

    1998-10-01

    A general survey of the possible approach for the next generation toroidal devices was made. Either surprisingly or obviously (depending on one`s view), the technical constraints along with the scientific considerations lead to a fairly limited set of systems for the most favorable approach for the next generation devices. Specifically if the magnetic field strength of 5 T or above is to be created by superconducting coils, it imposes minimum in the aspect ratio for the tokamak which is slightly higher than contemplated now for ITER design. The similar technical constraints make the minimum linear size of a stellarator large. Scientifically, it is indicated that a tokamak of 1.5 times in the linear dimension should be able to produce economically, especially if a hybrid reactor is allowed. For the next stellarator, it is strongly suggested that some kind of helical axis is necessary both for the (almost) absolute confinement of high energy particles and high stability and equilibrium beta limits. The author still favors a heliac most. Although it may not have been clearly stated in the main text, the stability afforded by the shearless layer may be exploited fully in a stellarator. (author)

  1. Distributed generation induction and permanent magnet generators

    CERN Document Server

    Lai, L

    2007-01-01

    Distributed power generation is a technology that could help to enable efficient, renewable energy production both in the developed and developing world. It includes all use of small electric power generators, whether located on the utility system, at the site of a utility customer, or at an isolated site not connected to the power grid. Induction generators (IGs) are the cheapest and most commonly used technology, compatible with renewable energy resources. Permanent magnet (PM) generators have traditionally been avoided due to high fabrication costs; however, compared with IGs they are more reliable and productive. Distributed Generation thoroughly examines the principles, possibilities and limitations of creating energy with both IGs and PM generators. It takes an electrical engineering approach in the analysis and testing of these generators, and includes diagrams and extensive case study examples o better demonstrate how the integration of energy sources can be accomplished. The book also provides the ...

  2. Large mass storage facility

    International Nuclear Information System (INIS)

    Peskin, A.M.

    1978-01-01

    The report of a committee to study the questions surrounding possible acquisition of a large mass-storage device is presented. The current computing environment at BNL and justification for an online large mass storage device are briefly discussed. Possible devices to meet the requirements of large mass storage are surveyed, including future devices. The future computing needs of BNL are prognosticated. 2 figures, 4 tables

  3. Random pulse generator

    International Nuclear Information System (INIS)

    Guo Ya'nan; Jin Dapeng; Zhao Dixin; Liu Zhen'an; Qiao Qiao; Chinese Academy of Sciences, Beijing

    2007-01-01

    Due to the randomness of radioactive decay and nuclear reaction, the signals from detectors are random in time. But normal pulse generator generates periodical pulses. To measure the performances of nuclear electronic devices under random inputs, a random generator is necessary. Types of random pulse generator are reviewed, 2 digital random pulse generators are introduced. (authors)

  4. Next-Generation Pathology.

    Science.gov (United States)

    Caie, Peter D; Harrison, David J

    2016-01-01

    The field of pathology is rapidly transforming from a semiquantitative and empirical science toward a big data discipline. Large data sets from across multiple omics fields may now be extracted from a patient's tissue sample. Tissue is, however, complex, heterogeneous, and prone to artifact. A reductionist view of tissue and disease progression, which does not take this complexity into account, may lead to single biomarkers failing in clinical trials. The integration of standardized multi-omics big data and the retention of valuable information on spatial heterogeneity are imperative to model complex disease mechanisms. Mathematical modeling through systems pathology approaches is the ideal medium to distill the significant information from these large, multi-parametric, and hierarchical data sets. Systems pathology may also predict the dynamical response of disease progression or response to therapy regimens from a static tissue sample. Next-generation pathology will incorporate big data with systems medicine in order to personalize clinical practice for both prognostic and predictive patient care.

  5. Exploring a Large Space of Small Games

    DEFF Research Database (Denmark)

    Barros, Gabriella; Togelius, Julian

    We explore the soundness and playability of randomly generated games expressed in the Video Game Description Language (VGDL). A grammar is defined for VGDL, which is able to express a large variety of simple arcade-like games, and random expansions of this grammar are fed to a VGDL interpreter...... and played with off the shelf agents. We see this work as the first step towards generating complete, playable games....

  6. Big Data Challenges for Large Radio Arrays

    Science.gov (United States)

    Jones, Dayton L.; Wagstaff, Kiri; Thompson, David; D'Addario, Larry; Navarro, Robert; Mattmann, Chris; Majid, Walid; Lazio, Joseph; Preston, Robert; Rebbapragada, Umaa

    2012-01-01

    Future large radio astronomy arrays, particularly the Square Kilometre Array (SKA), will be able to generate data at rates far higher than can be analyzed or stored affordably with current practices. This is, by definition, a "big data" problem, and requires an end-to-end solution if future radio arrays are to reach their full scientific potential. Similar data processing, transport, storage, and management challenges face next-generation facilities in many other fields.

  7. A third generation personality test

    OpenAIRE

    Sjöberg, Lennart

    2010-01-01

    The development of personality testing in the workplace has undergone three phases. The first generation of tests, such as Cattell’s 16 PF and the British test OPQ, was characterized by complex systems for the description of the personality. These systems were simplified in part by the following generation of the test, which was based on the five factor model but that model was simple only at the horizontal level. Beneath the five main factors were a large number of ancillary factors, usually...

  8. Induction generator models in dynamic simulation tools

    DEFF Research Database (Denmark)

    Knudsen, Hans; Akhmatov, Vladislav

    1999-01-01

    For AC network with large amount of induction generators (windmills) the paper demonstrates a significant discrepancy in the simulated voltage recovery after fault in weak networks when comparing dynamic and transient stability descriptions and the reasons of discrepancies are explained...

  9. Large N Scalars

    DEFF Research Database (Denmark)

    Sannino, Francesco

    2016-01-01

    We construct effective Lagrangians, and corresponding counting schemes, valid to describe the dynamics of the lowest lying large N stable massive composite state emerging in strongly coupled theories. The large N counting rules can now be employed when computing quantum corrections via an effective...

  10. Large bowel resection

    Science.gov (United States)

    ... blockage in the intestine due to scar tissue Colon cancer Diverticular disease (disease of the large bowel) Other reasons for bowel resection are: Familial polyposis (polyps are growths on the lining of the colon or rectum) Injuries that damage the large bowel ...

  11. Adaptive Large Neighbourhood Search

    DEFF Research Database (Denmark)

    Røpke, Stefan

    Large neighborhood search is a metaheuristic that has gained popularity in recent years. The heuristic repeatedly moves from solution to solution by first partially destroying the solution and then repairing it. The best solution observed during this search is presented as the final solution....... This tutorial introduces the large neighborhood search metaheuristic and the variant adaptive large neighborhood search that dynamically tunes parameters of the heuristic while it is running. Both heuristics belong to a broader class of heuristics that are searching a solution space using very large...... neighborhoods. The tutorial also present applications of the adaptive large neighborhood search, mostly related to vehicle routing problems for which the heuristic has been extremely successful. We discuss how the heuristic can be parallelized and thereby take advantage of modern desktop computers...

  12. Power Generation for River and Tidal Generators

    Energy Technology Data Exchange (ETDEWEB)

    Muljadi, Eduard [National Renewable Energy Lab. (NREL), Golden, CO (United States); Wright, Alan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Gevorgian, Vahan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Donegan, James [Ocean Renewable Power Company (ORPC), Portland, ME (United States); Marnagh, Cian [Ocean Renewable Power Company (ORPC), Portland, ME (United States); McEntee, Jarlath [Ocean Renewable Power Company (ORPC), Portland, ME (United States)

    2016-06-01

    Renewable energy sources are the second largest contributor to global electricity production, after fossil fuels. The integration of renewable energy continued to grow in 2014 against a backdrop of increasing global energy consumption and a dramatic decline in oil prices during the second half of the year. As renewable