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Sample records for lac des iles

  1. Milles Iles River : study of solutions to address critically low water levels; Riviere des Milles Iles : etude des solutions de soutien des etiages critiques

    Energy Technology Data Exchange (ETDEWEB)

    Cyr, J F; Fontin, M [Centre d' Expertise Hydrique du Quebec, Quebec, PQ (Canada). Service de la Securite des Barrages

    2006-07-01

    Water management for the Mille Iles River, which supplies drinking water to 400,000 people, was discussed with reference to solutions for critically low water flow which was experienced in 2001 and 2002. The river is part of the Lac des Deux Montagnes watershed in the region of Montreal which is characterized as a high population growth area. In the summer of 2001, municipalities served by the Mille Iles River were faced with problems in the supply of drinking water when the river flow reached only 13 cubic metres per second. The minimal values of flow observed for this time of year have rarely been under 20 cubic metres per second since 1970. The quality of water was reduced under such conditions of flow because the dilution of wastewater discharged into the river became so weak that the aging water treatment facilities had to work beyond their capacity. Quebec's Center of Water Expertise (CEHQ) intervened in an emergency measure to ensure water quality. This study investigated the following 3 possible scenarios for a solution to this problem: (1) to increase the Mille Iles River capacity at the Lac des Deux Montagnes outlet, (2) to reduce the flow discharged by the 3 other outlets of Lac des Deux Montagnes, and (3) to increase the inflow to Lac des Deux Montagnes from reservoirs located in the Ottawa River watershed. The first solution was favoured. 2 refs., 1 tab., 8 figs.

  2. Milles Iles River : study of solutions to address critically low water levels; Riviere des Milles Iles : etude des solutions de soutien des etiages critiques

    Energy Technology Data Exchange (ETDEWEB)

    Cyr, J.F.; Fontin, M. [Centre d' Expertise Hydrique du Quebec, Quebec, PQ (Canada). Service de la Securite des Barrages

    2006-07-01

    Water management for the Mille Iles River, which supplies drinking water to 400,000 people, was discussed with reference to solutions for critically low water flow which was experienced in 2001 and 2002. The river is part of the Lac des Deux Montagnes watershed in the region of Montreal which is characterized as a high population growth area. In the summer of 2001, municipalities served by the Mille Iles River were faced with problems in the supply of drinking water when the river flow reached only 13 cubic metres per second. The minimal values of flow observed for this time of year have rarely been under 20 cubic metres per second since 1970. The quality of water was reduced under such conditions of flow because the dilution of wastewater discharged into the river became so weak that the aging water treatment facilities had to work beyond their capacity. Quebec's Center of Water Expertise (CEHQ) intervened in an emergency measure to ensure water quality. This study investigated the following 3 possible scenarios for a solution to this problem: (1) to increase the Mille Iles River capacity at the Lac des Deux Montagnes outlet, (2) to reduce the flow discharged by the 3 other outlets of Lac des Deux Montagnes, and (3) to increase the inflow to Lac des Deux Montagnes from reservoirs located in the Ottawa River watershed. The first solution was favoured. 2 refs., 1 tab., 8 figs.

  3. Effet des conditions climatiques sur le niveau du lac Sidi Ali (Moyen Atlas, Maroc)

    OpenAIRE

    Sayad, Ahmed; Chakiri, Saïd; Martin, Claude; Bejjaji, Zohra; Echarfaoui, Hassan

    2012-01-01

    Le lac Sidi Ali est un lac naturel d'altitude (2070-2080 m), sans exutoire superficiel, déterminé par le barrage d'une coulée basaltique. Doté d'un bassin versant apparent de 15,6 km2, il est alimenté par des eaux de ruissellement et par des sources karstiques. Son niveau subit des variations très fortes, annuelles et interannuelles, sous le contrôle des conditions climatiques, et en particulier des pluies et de l'évapotranspiration. Les périodes de sécheresse qui ont marqué les trois dernièr...

  4. Fish communities in man-made lakes = Peuplements ichtyologiques des lacs de barrage

    OpenAIRE

    Jackson, P.N.B.; Marshall, B.E.; Paugy, Didier

    1988-01-01

    Il existe actuellement des réservoirs artificiels sur de nombreuses rivières africaines. Leur construction a modifié les conditions écologiques (facteurs édaphiques, apports en éléments nutritifs) et changé la composition des peuplements ichtyologiques ... Le barrage lui-même peut être un obstacle pour des poissons tels que les anguilles ou les mulets migrants depuis la mer et entraîner la disparition des espèces en amont ... Les lacs de barrage ont une vaste zone pélagique favorable au déve...

  5. Lac dayet Aoua (Maroc)

    African Journals Online (AJOL)

    Saad

    F.S.T. Fès - Sais, Université Sidi Mohammed Abdallah Fès, B.P. 2202, Maroc. 2Laboratoire des ... d'étude en complément de la composition phytoplanctonique et des analyses de la physico-chimie des eaux à l'entrée, au ... L'analyse des paramètres physico-chimiques, au point central du lac, a montré que l'eau du lac.

  6. Évaluation du niveau de pollution par les métaux lourds des lacs ...

    African Journals Online (AJOL)

    La présente étude a pour objectif principal d'évaluer le niveau de pollution métallique des lacs Bini et Dang (Ngaoundéré, Cameroun) à travers l'analyse des eaux et des sédiments de surface. La concentration des métaux lourds (Ni, Cr, Fe, Pb, Cd, Zn) a été mesurée par spectrophotométrie d'absorption atomique.

  7. Effet des conditions climatiques sur le niveau du lac Sidi Ali (Moyen Atlas, Maroc

    Directory of Open Access Journals (Sweden)

    Claude Martin

    2011-11-01

    Full Text Available Le lac Sidi Ali est un lac naturel d'altitude (2070-2080 m, sans exutoire superficiel, déterminé par le barrage d'une coulée basaltique. Doté d'un bassin versant apparent de 15,6 km2, il est alimenté par des eaux de ruissellement et par des sources karstiques. Son niveau subit des variations très fortes, annuelles et interannuelles, sous le contrôle des conditions climatiques, et en particulier des pluies et de l'évapotranspiration. Les périodes de sécheresse qui ont marqué les trois dernières décennies, se sont traduites par un abaissement du niveau de près de 7 m. Mais les précipitations abondantes des années 2008-09 et 2009-10 ont provoqué une nette remontée. Une régression multiple d'assez bonne qualité (r = 0,87 lie la variation annuelle du niveau (d'août à août à différents paramètres (conditions climatiques et niveau initial du lac.Lake Sidi Ali is a natural lake at high altitude (2070-2080 m, without surface outlet, determined by the dam of a basalt flow. With an apparent catchment of 15.6 km2, it is fed by runoff and karst springs. Its level shows strong annual and interannual variations, depending on weather conditions, particularly rainfall and evapotranspiration. Droughts that have marked the last three decades have resulted in a lowering of about 7 m of the water level. But heavy rainfall that occurred in 2008-09 and 2009-10 caused a marked rise. A multiple regression of sufficient quality (r = 0.87 binds the annual change (from august to august at differents parameters (weather conditions and initial level of the lake.

  8. Bilan des introductions de salmonidés dans les lacs et ruisseaux d'altitude des Hautes-Pyrénées

    Directory of Open Access Journals (Sweden)

    DELACOSTE M.

    1997-01-01

    Full Text Available Les introductions de Salmonidés ont été importantes au cours des 60 dernières années dans les lacs et ruisseaux d'altitude des Hautes-Pyrénées. Six espèces de Salmonidés ont été introduites dans des milieux qui, pour la plupart, étaient vierges de populations piscicoles : la truite commune (Salmo trutta L., la truite arc-en-ciel (Oncorhynchus mykiss Walbaum, l'omble de fontaine (Salvelinus fontinalis Mitchill, l'omble chevalier (Salvelinus alpinus L., le cristivomer (Salvelinus namaycush Walbaum et le splake (Salvelinus fontinalis x Salvelinus namaycush. Dans de très nombreux cas, ces introductions ont abouti à des acclimatations. En revanche, les naturalisations sont beaucoup plus rares. Seules les espèces lacustres (cristivomer et omble chevalier se sont naturalisées dans la majorité des lacs où elles ont été introduites. Les conditions de reproduction constituent le facteur clé permettant d'expliquer la naturalisation des espèces. En ruisseau, il faut y ajouter la compétition avec l'espèce indigène (la truite commune, la pression halieutique ainsi que les conditions hivernales très rigoureuses. Les incidences écologiques des introductions sur les populations de truites communes indigènes sont faibles. En revanche, elles ne sont pas négligeables pour les populations de batraciens. Cette politique d'introduction a largement participé au développement de l'halieutisme dans ces milieux d'altitude. En cela, les introductions ont parfaitement répondu aux objectifs halieutiques qu'on leur avait fixés. L'acquisition de connaissances sur l'ensemble de la chaîne pyrénéenne constitue aujourd'hui une étape incontournable pour une politique de gestion globale des introductions.

  9. L'habitat à une échelle globale : importance respective de l'immigration et de l'extinction pour les peuplements de poissons des petits lacs

    Directory of Open Access Journals (Sweden)

    TONN W. M.

    1995-04-01

    Full Text Available Les deux processus qui déterminent la structure des communautés dans les habitats insulaires sont l'immigration d'espèces vers une communauté et l'extinction de celles qui étaient présentes auparavant. Bien que l'immigration et l'extinction se produisent généralement à des échelles supérieures à celles qu'il est possible d'étudier avec des expériences plannifiées, les écologistes peuvent améliorer leur compréhension de ces processus par l'analyse des distributions observées ; l'isolation, le caractère discret et la réplication des systèmes insulaires présentent des avantages pour réaliser de telles analyses. Comme pour les communautés observées sur de vraies îles, la structure des peuplements de poissons dans les petits lacs forestiers est le résultat de l'immigration et de l'extinction. L'importance relative de ces processus peut dépendre des caractéristiques d'habitat des lacs et des espèces présentes, ainsi que du cadre régional et historique des lacs étudiés. Dans une région donnée, la composition des peuplements locaux de poissons peut être reliée à un ensemble particulier de conditions d'habitat et, dans la mesure où ces facteurs peuvent être liés à l'immigration et à l'extinction, il devrait être possible d'analyser les relations peuplement-environnement pour en déduire l'importance relative de ces processus dans la formation de peuplements locaux dans et entre les régions et les continents. Nous avons réalisé des analyses à large échelle des relations peuplement-environnement des petits lacs forestiers de quatre régions tempérées d'Europe et d'Amérique du Nord ; l'utilisation d'une série d'analyses canonique partielle des correspondances nous a permis de distinguer la variation due aux relations peuplements-environnement d'un ensemble de facteurs associés à l'immigration contre l'extinction. Les isolations passées et présentes varient selon les lacs et les régions, comme la

  10. Croissance et alimentation des larves de corégones (Coregonus lavaretus dans le lac d'Annecy de mars à avril 1996

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    CRETENOY L.

    1997-04-01

    Full Text Available La capture de plus de 400 larves de Coregonus lavaretus à 7 dates différentes dans le lac d'Annecy de mars à avril 1996 a permis d'étudier conjointement leur croissance et l'évolution de leur régime alimentaire. Les larves capturées ont une taille comprise entre 8,5 et 20 mm et un stade larvaire allant de 0 à 4, ces deux paramètres étant fortement liés. À mesure qu'elles grandissent, les larves qui consomment d'abord préférentiellement les stades larvaires des copépodes, puis leurs stades adultes, se nourrissent ensuite majoritairement de cladocères. La comparaison des structures de taille des proies ingérées et du zooplancton présent dans le lac conduit à évoquer la notion d'expérience acquise par les larves pour expliquer cette dérive alimentaire.

  11. Analyse und Bewertung von Naturgefahren als Grundlage für ein nachhaltiges Naturgefahrenmanagement in Gebirgssystemen SO-Kasachstans am Beispiel des Ile-Alatau

    OpenAIRE

    Yegorov, Alexandr

    2007-01-01

    Den Fragen der Erarbeitung des Naturgefahrenmanagements in Gebirgsystemen SO-Kasachstans und in den Ländern des Zentralasiens insgesamt wurde bisher keine gebührende Aufmerksamkeit zuteil. Die Naturkatastrophen der letzten Jahrzehnte sowie die Erfahrung mit Maßnahmen zum Schutz des Ile-Alatau vor Naturgefahren haben gezeigt, dass die Lösung dieser Probleme für die weitere nachhaltige Entwicklung dieser Region von erstrangiger Bedeutung ist. In dieser Arbeit wurde vom Autor umfangreiches Ma...

  12. cas du lac Fetzara, région de Annaba

    African Journals Online (AJOL)

    ruissellement, elles acquièrent une nouvelle composition différente de celle des eaux de pluie. Les apports par les précipitations météoriques. Chaque mois pluvieux a fait l'objet d'une analyse chimique et une moyenne des concentrations des eaux apportées au lac a été estimée. La quantité des éléments apportés par.

  13. Variabilité journalière de la qualité physico-chimique du lac M'koa ...

    African Journals Online (AJOL)

    d'enrichissement en matières organique, azote et phosphore capables d'influer sur la teneur de saturation en oxygène dissous. La Figure 4 montre des lavandiers communément appelés "fanico" exerçant leur activité quotidienne au lac. Cette activité est source d'enrichissement des eaux du lac. M'koa en phosphore et ...

  14. Analyses de la dégradation du lac Kinkony pour la conservation du ...

    African Journals Online (AJOL)

    Le lac Kinkony fait partie des habitats clefs pour la biodiversité du Complexe des ... provide favoured habitat for numerous endemic and endangered avian, fish ... on fauna is essential for developing regional conservation and natural resource ...

  15. Les méthodes de quantification économique des coûts sanitaires de la pollution atmosphérique : application à l’Ile-de-France

    OpenAIRE

    Géniaux, Ghislain; Rabl, Ari

    2007-01-01

    Cet article passe en revue les méthodes de quantification économique des coûts sanitaires de la pollution atmosphérique. Ces méthodes sont appliquées à l’Ile-de-France, à partir de l’étude épidémiologique ERPURS sur les effets aiguës de la pollution sur la santé, et d’autres études internationales. La plus grande partie des coûts est imputable aux effets chroniques des particules sur la mortalité. This pape reviews the methods that can be used for evaluating the costs of health damages due...

  16. République de Djibouti : lac Assal [بحيرة عسل

    OpenAIRE

    Pouyllau , Stéphane

    2009-01-01

    Vue des berges sud-est du lac Assal (République de Djibouti) le 11 novembre 2009. Le Lac Assal est un lac salé endoréique situé au fond du golfe du Ghoubbet-el-Kharab. D'une superficie de 54 km2 et fermé de la mer par le volcan Ardoukôba, sont altitude est de -153m sous le niveau de la mer.

  17. Dynamique de la nappe et qualites physico-chimiques des eaux ...

    African Journals Online (AJOL)

    resultat est conforme a celui des cartes piezo- metriques elaborees en 1993 et 2007 [19,20]; done la nappe suit le modele topographique et le lac constitue une zone de convergence des eaux. ©UBMA-2013. 88. F. Zahi et al. L' examen des cartes piezometriques montrent que les parties Sud et Sud-Est du lac Fetzara se.

  18. Du Lac de Geneve au Lac Baikal: deux metropoles en construction

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    Guy Mettan

    2006-08-01

    Full Text Available En apparence, Geneve et Irkutsk n'ont rien en commun. A part une amitie reciproque et la proximite d'un lac, il est difficile de trouver des points communs entre la Suisse francophone, dont Geneve est la ville le plus importante, et la Siberie centrale, dont Irkutsk, est la capitale. Et pourtant les deux regions, malgre les differences de taille, de densite de la population, de climat, d'economie et de traditions culturelles, sont confrontees au meme probleme: elles sont trop petites et trop limitees pour assurer, avec leurs seuls moyens, leur avenir et elles doivent imperativement s'unir a des villes voisines pour renforcer leur statut de metropole regionale et s'imposer face aux regions et aux pays concurrents.C'est ainsi qu'Irkutsk projette de s'unir aux villes voisines d'Angarsk et de Chelekhov pour constituer une megapole au c?ur de la Siberie, tandis qu'a Geneve le debat fait rage pour trouver des solutions a l'exiguite geographique et a l'insuffisance des moyens face aux grandes regions metropolitaines de France, d'Italie et d'Allemagne.Ce debat est propre a toute la Suisse. Malgre sa petitesse, la Suisse est divisee en 26 cantons. Ces unites administratives sont jugees trop couteuses, trop petites, trop lourdes et trop compliquees pour assurer l'avenir economique et meme politique du pays. De nombreux groupes de reflexion proposent donc de reduire ce nombre a 3, 5 ou 10 grandes provinces selon les cas. En Suisse, romande, il y a dix ans, des mouvements politiques ont meme lance l'idee de fusionner les cantons de Vaud (dont Lausanne est la capitale et de Geneve. Mais l'echec a ete fracassant : le peuple des deux cantons a refuse cette option a 80% des voix. On cherche donc d'autres solutions.Les discussions s'orientent desormais autour de la constitution d'une grande metropole lemanique qui regrouperait les deux grandes villes de Geneve et Lausanne et les villes plus petites de Montreux, Vevey, Nyon ainsi que la ville francaise d

  19. Regard sur la participation de populations marginalisées à la recherche-action. Le cas des squatteurs en Ile-de-France The participation of Marginalised populations in research-action: a case study of squatters in the Ile-de-France region (Paris and surrounding region

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    Lionel Pourtau

    2011-05-01

    Full Text Available La recherche-action comporte deux caractéristiques principales : elle met en œuvre la collaboration entre plusieurs types d’acteurs et vise une transformation de la réalité sociale. Elle possède des forces et des faiblesses différentes de la recherche à objectif strictement cognitif. L’article rend compte d’une recherche-action menée par des sociologues, des intervenants sociaux et des populations vivant en squats en Ile-de-France. Les auteurs analysent les enjeux méthodologiques qui se sont posés sur ce terrain particulier relevant de la sociologie de la déviance. Ceux-ci sont liés, notamment, à la participation de chaque groupe d’acteurs aux différentes étapes de la recherche, à la présence d’intérêts différents portés par chacun d’entre eux, et à la conciliation entre les principes habituellement de rigueur dans l’enquête sociologique et les principes de la recherche-action.Research-Action has two main objectives: to allow different players to cooperate, and to transform social reality. This methodology has both the strengths and the weaknesses of strictly cognitive research. In this article, the authors discuss a research-action project which brought together sociologists, social workers and squatters from the Ile-de-France region (Paris and surrounding region. Methodological issues that arise specifically in the context of deviance are addressed, notably the participation of the different players at different stages of the research project, their different areas of interest, as well as the reconciliation between more conventional sociological research and the principles of research-action.

  20. Utilization of Iles-Iles and Sorghum Starch for Bioethanol Production

    Directory of Open Access Journals (Sweden)

    Kusmiyati Kusmiyati

    2014-05-01

    Full Text Available The aims of this study were to convert the starches from iles-iles tubers (Amorphophalus campanulatus and sorghum grains (Sorghum bicolor L into bioethanol as an alternative energy. Both of these agricultural products contains a high content starches and they do not use as the major foods in Indonesia. To find out the maximum ethanol concentration and yield, both the raw materials were converted to ethanol on various process variables including the concentration of flour substrate solution (100-300 g/L, β-amylase enzyme concentration (0.8 - 6.4 ml/kg of flour , the  concentration of dry yeast S. cerevisiae (2-15 g, and fermentation time (72-168 hours. The results showed that at the flour substrate concentration of 250 g/L produced the maximum ethanol contents of 100.29 g/L and 95.11 g/L   for iles-iles and sorghum, respectively. Effect of β-amylase enzyme in the saccharification process showed that at concentration  of 3.2 ml/kg  the maximum reducing sugar content of 204.94 g/L and 193.15 g/L  for iles-iles and sorghum substrate, respectively were generated therefore it was corresponding to the maximum ethanol production. The concentration effect of dry yeast S. cerevisiae in the fermentation stage for the iles-iles and sorghum substrate revealed that the maximum ethanol obtained at 5 g yeast activated in 100 ml medium starter resulted the highest ethanol content 100.29 g/L 95.11 g/L for iles-iles and sorghum substrate, respectively. To determine the effect of fermentation time on ethanol yield from iles-iles and sorghum substrate, the fermentation process were performed at 3, 5, and 7 days. The maximum ethanol fermentation was obtained at 5 days fermentation. The ethanol yield is calculated by weight of ethanol is formed (g divided by the weight of flour (g. Based on the experiment results, conducted, generally the highest ethanol yield of iles-iles was higher than that of sorghum flour. The highest yield (g/g iles-iles and sorghum

  1. Modeling of pollution aerosols in Ile-de-France; Modelisation des aerosols de pollution en Ile-de-France

    Energy Technology Data Exchange (ETDEWEB)

    Hodzic, A

    2005-10-15

    The modeling of aerosols is a major stake in the understanding of the emission processes and evolution of particulates in the atmosphere. However, the parameterizations used in today's aerosol models still comprise many uncertainties. This work has been motivated by the need of better identifying the weaknesses of aerosols modeling tools and by the necessity of having new validation methods for a 3D evaluation of models. The studies have been carried out using the CHIMERE chemistry-transport model, which allows to simulate the concentrations and physico-chemical characteristics of pollution aerosols at the European scale and in Ile-de-France region. The validation approach used is based on the complementarity of the measurements performed on the ground by monitoring networks with those acquired during the ESQUIF campaign (study and simulation of air quality in Ile-de-France), with lidar and photometric measurements and with satellite observations. The comparison between the observations and the simulations has permitted to identify and reduce the modeling errors, and to characterize the aerosol properties in the vicinity of an urban area. (J.S.)

  2. Modeling of pollution aerosols in Ile-de-France; Modelisation des aerosols de pollution en Ile-de-France

    Energy Technology Data Exchange (ETDEWEB)

    Hodzic, A

    2005-10-15

    The modeling of aerosols is a major stake in the understanding of the emission processes and evolution of particulates in the atmosphere. However, the parameterizations used in today's aerosol models still comprise many uncertainties. This work has been motivated by the need of better identifying the weaknesses of aerosols modeling tools and by the necessity of having new validation methods for a 3D evaluation of models. The studies have been carried out using the CHIMERE chemistry-transport model, which allows to simulate the concentrations and physico-chemical characteristics of pollution aerosols at the European scale and in Ile-de-France region. The validation approach used is based on the complementarity of the measurements performed on the ground by monitoring networks with those acquired during the ESQUIF campaign (study and simulation of air quality in Ile-de-France), with lidar and photometric measurements and with satellite observations. The comparison between the observations and the simulations has permitted to identify and reduce the modeling errors, and to characterize the aerosol properties in the vicinity of an urban area. (J.S.)

  3. Déclin et restauration de la population de truites lacustres (Salmo trutta lacustris L. du lac de Constance

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    RUHLÉ C.

    1990-10-01

    Full Text Available Le déclin de la population de truites migratrices du lac de Constance a débuté vers 1950 quand un barrage a été construit sur le Rhin, affluent principal de ce lac, coupant ainsi l'accès aux plus importantes frayères. Ceci a suffi de prétexte pour renoncer à une longueur de capture garantissant la reproduction naturelle. Par la suite, la population en train de diminuer a servi de justification pour des déversements importants de truites arc-en-ciel. Un désintérêt croissant pour le maintien de frayères dans les affluents secondaires a, finalement, contribué à la baisse des captures de 12.000 kg à 3.000 kg entre 1950 et 1980.Les mesures réalisées au cours des dernières années pour restaurer la population de truites lacustres ont du succès. Il s'agit surtout de : — la détermination d'une nouvelle longueur de capture ainsi que de périodes de protection respectant la reproduction des truites migrant à longue et à courte distance,— l'élevage de stocks de géniteurs, — les déversements forcés et effectués surtout en affluents (au lieu du lac,— l'interdiction d'immersions de truites arc-en-ciel,— l'abolition de barrages. Le succès se manifeste par un nombre croissant de truites observées frayant dans les affluents ainsi que par des captures de plus en plus nombreuses faites par la pêche professionnelle.

  4. OPDA-Ile a new JA-Ile-independent signal?

    Czech Academy of Sciences Publication Activity Database

    Wasternack, Claus; Hause, B.

    2016-01-01

    Roč. 11, č. 11 (2016), č. článku e1253646. ISSN 1559-2316 R&D Projects: GA MŠk(CZ) LO1204; GA ČR GA14-34792S Institutional support: RVO:61389030 Keywords : allene oxide cyclase * 12-oxo-phytodienoic acid * arabidopsis -thaliana * stress responses * jasmonic acid * cyclopentenones * perception * coronatine * repressors * oxylipins * 12-oxo-phytodienoic acid (OPDA) * JA-Ile perception * jasmonic acid (JA) * jasmonoyl-isoleucine (JA-Ile) * OPDA-Ile-induced gene expression * SCFCOI1-JAZ coreceptor complex Subject RIV: EB - Genetics ; Molecular Biology

  5. (Vitaceae) dans le Parc National des Iles de la M

    African Journals Online (AJOL)

    SARAH

    31 juil. 2015 ... 3Ecole Régionale Post-Universitaire d'Aménagement et de gestion Intégrés des Forêts et ... Méthodologie et résultats : Des essais de contrôle biologique et physique ont été testés. ..... Dynamique des populations de l'arbre.

  6. REPEUPLEMENTS EN ALEVINS NOURRIS ET DÉMOGRAPHIE DE LA POPULATION DE TRUITE (SALMO TRUTTA L. DANS LE REDON, UN AFFLUENT DU LAC LÉMAN INTERROMPU PAR UN OBSTACLE

    Directory of Open Access Journals (Sweden)

    CHAMPIGNEULLE A.

    2003-01-01

    Full Text Available La démographie d’une population de truite (Salmo trutta L. a été étudiée, dans un contexte de repeuplements en alevins nourris, sur le Redon, un affluent du lac Léman. On trouve sur le Redon une situation typique de nombreux affluents du Léman : une zone aval ouverte sur le lac mais rapidement interrompue par un obstacle empêchant la remontée des truites de lac. Des relâchers d’alevins nourris issus d’œufs de géniteurs sauvages de truite de lac ou de géniteurs domestiques, pratiqués en fin de printemps-début été à des densités de 40-60 ind./100 m2, fournissent un recrutement additionnel important pouvant constituer la part dominante du peuplement automnal en 0 +, puis 1 +. Sur les zones ouvertes à la pêche, colonisées ou non par la truite de lac, la densité de la population automnale en place s’effondre entre le stade 1 + et les stades > 1 +. Les résultats comparatifs entre zones ouvertes ou fermées à la pêche indiquent que la pêche peut être un facteur de mortalité important. La dynamique comparée des truites d’origine lacustre ou sédentaire suggère l’existence d’un taux de sédentarisation plus faible pour les 1 + issus de truites de lac comparativement aux 1 + issus de la fraie de truites sédentaires en zone de réserve. Une expérimentation suggère l’existence de mouvements de dévalaison ayant lieu avant octobre et touchant préférentiellement les 0 + d’origine lacustre ayant eu la croissance initiale la plus forte. L’étude montre que : - des alevins nourris d’origine lacustre ou domestique, relâchés en fin de printemps-début été, fournissent des géniteurs de truite de lac remontant dans la rivière de relâcher, avec cependant une proportion moindre (4 fois dans le cas de l’origine domestique comparativement à l’origine lacustre. Malgré leur forte contribution aux stades de juvéniles 0 + et 1 +, les alevins domestiques de pisciculture contribuent peu aux retours de g

  7. Circuit court du marché des produits agricoles : pour une gestion ...

    African Journals Online (AJOL)

    pour un développement durable au Lac Alaotra. . Cirad-Inra-SupAgro,. Montpellier, FR. Available at . Penot, É., Dabat, M.-H., Rakotoarimanana, A. & Grandjean, P. 2014. L'évolution des pratiques agricoles au lac Alaotra à Madagascar. Une approche par les temporalités.

  8. Données préliminaires sur la diversité du zooplancton du lac Nokoué

    African Journals Online (AJOL)

    SARAH

    31 juil. 2017 ... contribuera davantage à la compréhension de la dynamique de cette communauté biologique du lac. Mots clés ... dans une perspective de gestion durable de la .... ramenés au Laboratoire de Contrôle de Qualité des Eaux.

  9. A Pleistocene record of a rare endemic gymnosperm, Neocallitropsis pancheri (Cupressaceae), from the Plaine des Lacs, New Caledonia

    International Nuclear Information System (INIS)

    Suprin, B.; Hope, G.

    2001-01-01

    A log found submerged in a small lake in south east New Caledonia has been identified as the now rare endemic conifer Neocallitropsis pancheri (Carr.) Laubenf. (Cupressaceae). Tree ring counts are in reasonable agreement with two radiocarbon dates from the centre and outer wood of the log, indicating an age at death of about 250 years. The tree lived about 12,000 C14 years ago and was as large as modern individuals of presumed similar age. Widespread erosion and the replacement of mixed rainforest by Gymnostoma dominated maquis, associated with episodes of fire, occurred in this area for an unknown period after 25,000 BP. The growth of this moisture dependant and fire sensitive gymnosperm by 12,000 BP suggests that a moister and more stable climate may have been re-established before the start of the Holocene. The species is now almost removed from the Plaine des Lacs, possibly being excluded by widespread natural fires in the Holocene, and those associated with European logging in the early colonial period

  10. Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI.

    Directory of Open Access Journals (Sweden)

    Kalle Kipper

    Full Text Available The lactose operon repressor protein LacI has long served as a paradigm of the bacterial transcription factors. However, the mechanisms whereby LacI rapidly locates its cognate binding site on the bacterial chromosome are still elusive. Single-molecule fluorescence imaging approaches are well suited for the study of these mechanisms but rely on a functionally compatible fluorescence labeling of LacI. Particularly attractive for protein fluorescence labeling are synthetic fluorophores due to their small size and favorable photophysical characteristics. Synthetic fluorophores are often conjugated to natively occurring cysteine residues using maleimide chemistry. For a site-specific and functionally compatible labeling with maleimide fluorophores, the target protein often needs to be redesigned to remove unwanted native cysteines and to introduce cysteines at locations better suited for fluorophore attachment. Biochemical screens can then be employed to probe for the functional activity of the redesigned protein both before and after dye labeling. Here, we report a mutagenesis-based redesign of LacI to enable a functionally compatible labeling with maleimide fluorophores. To provide an easily accessible labeling site in LacI, we introduced a single cysteine residue at position 28 in the DNA-binding headpiece of LacI and replaced two native cysteines with alanines where derivatization with bulky substituents is known to compromise the protein's activity. We find that the redesigned LacI retains a robust activity in vitro and in vivo, provided that the third native cysteine at position 281 is retained in LacI. In a total internal reflection microscopy assay, we observed individual Cy3-labeled LacI molecules bound to immobilized DNA harboring the cognate O1 operator sequence, indicating that the dye-labeled LacI is functionally active. We have thus been able to generate a functional fluorescently labeled LacI that can be used to unravel mechanistic

  11. Bioethanol Production from Iles-Iles (Amorphopallus campanulatus Flour by Fermentation using Zymomonas mobilis

    Directory of Open Access Journals (Sweden)

    Kusmiyati Kusmiyati

    2016-02-01

    Full Text Available Due to the depletion of fossil oil sources, Indonesia attempts to search new source of bioenergy including bioethanol. One of this sources is Iles-iles tubers (Amorphophallus campanulatus, which is abundantly available in Java Indonesia. The carbohydrate content in Iles-Iles tuber flour was 77% and it can be converted to ethanol by three consecutive steps methods consist of liquefaction-saccharification using α and β-amylase, respectively and then followed by fermentation by using Z. mobilis. The objective of this research was to convert the Iles-iles flour to bioethanol by fermentation process with Z.mobilis. The ethanol production process was studied at various starch concentration 15-30% g/L, Z. mobilis concentration (10-40% and pH fermentation of (4-6. The result showed that the yield of bioethanol (10.33% was the highest at 25% starch concentration and 25% of Z.mobilis concentration. The optimum conditions was found at 4.5, 30°C, 10%, 120 h for pH, temperature, Z. mobilis concentration and fermentation time, respectively  at which  ACT tuber flour produced a maximum ethanol of 10.33 % v/v.Article History: Received November 12nd 2015; Received in revised form January 25th 2016; Accepted January 29th 2016; Available online How to Cite This Article: Kusmiyati , Hadiyanto,H  and Kusumadewi, I (2016. Bioethanol Production from Iles-Iles (Amorphopallus campanulatus Flour by Fermentation using Zymomonas mobilis. Int. Journal of Renewable Energy Development, 9(1, 9-14 http://dx.doi.org/10.14710/ijred.5.1.9-14 

  12. Programme Sahamalaza-Iles Radama de l’AEECL : étude et conservation des espèces menacées d’extinction de lémuriens dans le nord-ouest de Madagascar AEECL’s Sahamalaza-Iles Radama Program: study and conservation of threatened species of lemurs in north-west of Madagascar.

    Directory of Open Access Journals (Sweden)

    Alice Dumoulin

    2011-10-01

    Full Text Available L’AEECL, Association Européenne pour l’Etude et la Conservation des Lémuriens, est un consortium de parcs zoologiques et d’universités européennes mettant en commun leurs connaissances et leurs efforts en faveur de projets de recherche et de protection des lémuriens menacés d’extinction de Madagascar depuis plus de trente ans. Pour ce faire, l’AEECL mène ou finance des études afin d’améliorer les connaissances scientifiques concernant les lémuriens. Ces informations sont indispensables pour mettre en place les mesures concrètes adaptées pour protéger ces animaux. Ses travaux ont notamment aidé à la reconnaissance de la péninsule de Sahamalaza en tant que réserve de biosphère de l’UNESCO, en 2001 et à la création du parc national Sahamalaza-Iles Radama, en 2007, principal site de recherches menées par l’association. De plus l’AEECL met un point d’honneur à impliquer la population locale. Des associations communautaires locales ont été créées dans les villages de quatre communes. Elles ont le pouvoir de gérer les ressources naturelles de leur juridiction de façon durable.The European Association for the Study and Conservation of Lemurs (Association Européenne pour l’Etude et la Conservation des Lémuriens, AEECL is a consortium of European zoological gardens and universities who have joined forces to carry out conservation and research projects for Madagascar’s highly endangered lemurs since more than 30 years. AEECL implements or finances various different research projects to improve the scientific knowledge of lemurs. Information is essential to be able to develop comprehensive conservation and management plans to protect these animals. The work of AEECL has led to the implementation of a UNESCO Biosphere Reserve in Sahamalaza in 2001 and to the creation of the Sahamalaza-Iles Radama National Park in 2007. In addition to the research, AEECL is carrying out a community-based natural resource

  13. Comparasion of iles-iles and cassava tubers as a Saccharomyces cerevisiae substrate fermentation for bioethanol production

    Directory of Open Access Journals (Sweden)

    KUSMIYATI

    2010-01-01

    Full Text Available Kusmiyati (2010 Comparasion of iles-iles and cassava tubers as a Saccharomyces cerevisiae substrate fermentation for bioethanol production. Nusantara Bioscience 2: 7-13. The production of bioethanol increase rapidly because it is renewable energy that can be used to solve energy crisis caused by the depleting of fossil oil. The large scale production bioethanol in industry generally use feedstock such as sugarcane, corn, and cassava that are also required as food resouces. Therefore, many studies on the bioethanol process concerned with the use raw materials that were not competing with food supply. One of the alternative feedstock able to utilize for bioethanol production is the starchy material that available locally namely iles-iles (Amorphophallus mueller Blum. The contain of carbohydrate in the iles-iles tubers is around 71.12 % which is slightly lower as compared to cassava tuber (83,47%. The effect of various starting material, starch concentration, pH, fermentation time were studied. The conversion of starchy material to ethanol have three steps, liquefaction and saccharification were conducted using α-amylase and amyloglucosidase then fermentation by yeast S.cerevisiaie. The highest bioethanol was obtained at following variables starch:water ratio=1:4 ;liquefaction with 0.40 mL α-amylase (4h; saccharification with 0.40 mL amyloglucosidase (40h; fermentation with 10 mL S.cerevisiae (72h producing bioethanol 69,81 g/L from cassava while 53,49 g/L from iles-iles tuber. At the optimum condition, total sugar produced was 33,431 g/L from cassava while 16,175 g/L from iles-iles tuber. The effect of pH revealed that the best ethanol produced was obtained at pH 5.5 during fermentation occurred for both cassava and iles-iles tubers. From the results studied shows that iles-iles tuber is promising feedstock because it is producing bioethanol almost similarly compared to cassava.

  14. Caractérisation des sables et morphologie du fond du lac du ...

    African Journals Online (AJOL)

    Une analyse sédimentologique et minéralogique réalisée sur un cycle hydrologique entre octobre 2004 et août 2005 a permis d\\'évaluer les charges solides en suspension et de caractériser les sédiments du lac du barrage de Taabo. La concentration moyenne en matières en suspension (12 mg.L-1) et la turbidité ...

  15. Caractérisation des sables et morphologie du fond du lac du ...

    African Journals Online (AJOL)

    Administrateur

    Une analyse sédimentologique et minéralogique réalisée sur un cycle hydrologique entre octobre 2004 et août 2005 a permis d'évaluer les charges solides en suspension et de caractériser les sédiments du lac du barrage de Taabo. La concentration moyenne en matières en suspension (12 mg.L-1) et la turbidité ...

  16. Study synthesis: which place for the methanation of wastes in Ile de France; Synthese de l'etude: quelle place pour la methanisation des dechets en Ile de France

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    In order to complete the studies realized on the methanation topic, a growing channel of bio-wastes treatment in Europe, the Arene and Ordif decided to realize this document of information, for deciders, on the evaluation of the household, industrial and agricultural wastes valorization by the methane. It presents the methanation principle, the situation in Europe and France, the Ile de France installation, the possible development and capacities in Ile de France and the perspectives. (A.L.B.)

  17. Dynamique de structuration spatio-temporelle des populations de ...

    African Journals Online (AJOL)

    Dynamique de structuration spatio-temporelle des populations de familles de macroinvertébrés dans un continuum lac de barrage-effluent-fleuve issu de périmètre irrigué. Bassin de la Volta (Burkina Faso)

  18. etude physico-chimique et parasitologique des eaux usees

    African Journals Online (AJOL)

    AISA

    pollution ont été relativement faibles, comparativement à la moyenne des concentrations habituellement rencontrées pour les ... Mots clés : Pollution, eaux usées, physico-chimie, Helminthes, lac Fouarat, Maroc. ...... Paris, 1383 p. SDNAL.

  19. Foules, espaces publics urbains et apprentissage de la co-présence chez les adolescents des quartiers populaires d’Ile de France Crowds, urban public spaces and learning co-presence: the Case of the Adolescents residing in the popular districts of the Ile-de-France

    Directory of Open Access Journals (Sweden)

    Nicolas Oppenchaim

    2010-09-01

    Full Text Available Cet article porte sur le rapport qu’entretiennent les adolescents à la foule urbaine et sur la manière dont ils apprennent à y trouver une place. Pour ce faire nous procéderons en trois temps. Nous exposerons tout d’abord en quoi, s’appuyant sur les travaux de R. Park et G. Tarde, Isaac Joseph fait du passage de la foule au public une des caractéristiques majeures des sociétés contemporaines. Ce passage concerne à la fois l’espace métaphorique des mobilisations collectives, mais également l’espace urbain : le propre des villes contemporaines n’est pas les grands rassemblements de foule dominés par les émotions, mais les espaces publics, lieux de co-présence organisés autour de l’inattention civile. Ces espaces offrent ainsi des possibilités de rencontre tout en garantissant un droit à l’intimité.Cependant nous montrerons dans un second temps que cette perception apaisée des grands rassemblements dans la ville ne va pas de soi, notamment à l’adolescence. Il est donc nécessaire d’introduire la problématique de l’apprentissage dans les réflexions sur les espaces publics urbains. Ainsi, une partie des adolescents des quartiers populaires d’Ile de France ont une perception de ces lieux de co-présence très proche de celle développée dans les discours du 18ème et 19ème siècle sur la peur des foules urbaines. Plus largement, les adolescents de quartiers populaires se différencient dans leurs discours par quatre grandes positions idéal-typiques vis-à-vis des foules urbaines : « foule source d’animation potentielle », « foule indifférente », « foule menaçante », ou « foule espace public ». Nous verrons alors dans un troisième temps que ce rapport différencié des adolescents à la foule est à mettre en relation avec le lien entretenu avec le quartier de résidence et les modalités d’apprentissage de la mobilité.This article aims at further documenting the relationship of

  20. Natural LacI from E. coli Yields Faster Response and Higher Level of Expression than the LVA-Tagged LacI

    DEFF Research Database (Denmark)

    Andreassen, Patrick Rosendahl; Fredberg, Sofie; Horan, Mattias

    2014-01-01

    The lac promoter is one of the most commonly used promoters for expression control of recombinant genes in E. coli. In the absence of galactosides, the lac promoter is repressed by its repressor protein LacI. Since the lac promoter is regulated by a repressor, overexpression of LacI is necessary...

  1. Un indice biologique lacustre basé sur l'examen des peuplements de mollusques

    Directory of Open Access Journals (Sweden)

    MOUTHON J.

    1993-10-01

    Full Text Available Les mollusques (limnées et pisidies sont potentiellement capables de coloniser la zone profonde des systèmes lacustres. Lorsque le milieu se dégrade (installation puis développement de conditions hypoxiques au niveau de son hypolimnion et accumulation de matière organique dans ses sédiments profonds on observe une diminution de plus en plus importante de l'amplitude bathymétrique des espèces, ainsi qu'une disparition progressive ordonnée de la zone profonde à la zone littorale des Gastéropodes puis des pisidies (Bivalves. Dans ce processus de simplification croissante des malacocénoses, différents états ont été reconnus. A partir de ces observations, un tableau de détermination d'un indice malacologique de qualité des systèmes lacustres (IMOL, variant de 0 à 8 est proposé. Le calcul de l'indice est effectué à partir de la détermination des genres et du critère présence-absence. Un protocole d'échantillonnage standard des zones profonde, sublittorale et littorale permet d'obtenir le matériel biologique nécessaire à la mise en oeuvre de cette méthode. Cet indice qui vise à définir d'une manière simple et rapide l'état biologique global d'un lac s'applique aux milieux de petites dimensions (S ≤500 hect., de profondeur maximale supérieure à 10 m et d'altitude ne dépassant guère 1000 m. Toutefois, une extension de cette technique aux milieux profonds de grandes dimensions (lac Léman, Bourget, ... d'une part et aux plans d'eau apparentés aux étangs d'autre part est envisageable. Les résultats obtenus pour une trentaine de lacs sont présentés.

  2. lac operon induction in Escherichia coli: Systematic comparison of IPTG and TMG induction and influence of the transacetylase LacA.

    Science.gov (United States)

    Marbach, Anja; Bettenbrock, Katja

    2012-01-01

    Most commonly used expression systems in bacteria are based on the Escherichia coli lac promoter. Furthermore, lac operon elements are used today in systems and synthetic biology. In the majority of the cases the gratuitous inducers IPTG or TMG are used. Here we report a systematic comparison of lac promoter induction by TMG and IPTG which focuses on the aspects inducer uptake, population heterogeneity and a potential influence of the transacetylase, LacA. We provide induction curves in E. coli LJ110 and in isogenic lacY and lacA mutant strains and we show that both inducers are substrates of the lactose permease at low inducer concentrations but can also enter cells independently of lactose permease if present at higher concentrations. Using a gfp reporter strain we compared TMG and IPTG induction at single cell level and showed that bimodal induction with IPTG occurred at approximately ten-fold lower concentrations than with TMG. Furthermore, we observed that lac operon induction is influenced by the transacetylase, LacA. By comparing two Plac-gfp reporter strains with and without a lacA deletion we could show that in the lacA(+) strain the fluorescence level decreased after few hours while the fluorescence further increased in the lacA(-) strain. The results indicate that through the activity of LacA the IPTG concentration can be reduced below an inducing threshold concentration-an influence that should be considered if low inducer amounts are used. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. Properties of BL Lac objects

    International Nuclear Information System (INIS)

    Wolfe, A.M.; Pittsburgh, University, Pittsburgh, Pa.)

    1980-01-01

    The properties of BL Lacertae objects are examined in light of their recently realized similarities to quasars and associations with galactic radiation. The criteria typically used to define BL Lac objects are analyzed, with attention given to radio spectra, optical continual, radio and optical variability, optical polarization and emission lines, and evidence that BL Lac objects and optically violent variables represent the most compact and strongly variable sources among the general class of quasars is discussed. Connections between BL Lac objects and the galaxies in which they have been observed to be embedded are discussed and it is pointed out that no low-luminosity quasars have been found to be associated with first-ranked giant ellipticals. Future observations which may clarify the properties and relationships of BL Lac objects are indicated

  4. The Discovery of Low-Luminosity BL Lacs

    Science.gov (United States)

    Rector, Travis A.; Stocke, John T.

    1995-12-01

    Many of the properties of BL Lacs have become explicable in terms of the ``relativistic beaming'' hypothesis whereby BL Lacs are ``highly beamed'' FR-I radio galaxies (i.e. our line of sight to these objects is nearly along the jet axis). Further, radio-selected BL Lacs (RBLs) are believed to be seen nearly ``on-axis'' (the line-of-sight angle theta ~ 8deg ) while X-ray selected BL Lacs (XBLs) are seen at larger angles (theta ~ 30deg ; the X-ray emitting jet is believed to be less collimated). However, a major problem with this model was that a transition population between beamed BL Lacs and unbeamed FR-Is had not been detected. Low-luminosity BL Lacs may be such a transition population, and were predicted to exist by Browne and Marcha (1993). We present ROSAT HRI images, VLA radio maps and optical spectra which confirm the existence of low-luminosity BL Lacs, objects which were previously mis-identified in the EMSS catalog as clusters of galaxies. Thus our results strengthen the relativistic beaming hypothesis.

  5. Distribution saisonnière du phytoplancton en fonction des ...

    African Journals Online (AJOL)

    SARAH

    25 avr. 2013 ... caractéristiques physico-chimiques du lac de Zowla ..... Figure 2 : Plan factoriel F1xF2 des variables en Août 2009 (en haut) et en Février 2010 (en bas). ..... Tesis. (Biólogo Marino), Facultad de Biología Marina,. Universidad ...

  6. Indian Americans at Mille Lacs.

    Science.gov (United States)

    Holbert, Victoria L.; And Others

    The Training Center for Community Programs prepared a report on the Mille Lacs (Chippewa) Reservation in Minnesota. Data for the report were from 2 separate sources: a survey conducted by the Training Center with the assistance of the Mille Lacs community action program (1967) and an attitudinal survey conducted by Victoria Holbert during 1969.…

  7. In vivo expression of the lacY gene in two segments leads to functional lac permease

    International Nuclear Information System (INIS)

    Bibi, E.; Kaback, H.R.

    1990-01-01

    The lacY gene of Escherichia coli was cut into two approximately equal-size fragments with Afl II and subcloned individually or together under separate lac operator/promoters in plasmid pT7-5. Under these conditions, lac permease is expressed in two portions: (i) the N-terminal portion (the N terminus, the first six putative transmembrane helices, and most of putative loop 7) and (ii) the C-terminal portion (the last six putative transmembrane helices and the C terminus). Cells harboring pT7-5 encoding both fragments transport lactose at about 30% the rate of cells expressing intact permease to a comparable steady-state level of accumulation. In contrast, cells expressing either half of the permease independently do not transport lactose. As judged by [ 35 S]methionine labeling and immunoblotting, intact permease in completely absent from the membrane of cells expressing lacY fragments either individually or together. Thus, transport activity must result from an association between independently synthesized pieces of lac permease. When the gene fragments are expressed individually, the N-terminal portion of the permease is observed inconsistently, and the C-terminal portion is not observed. When the gene fragments are expressed together, polypeptides identified as the N- and C-terminal moieties of the permease are found in the membrane. It is concluded that the N- or C-terminal halves of lac permease are proteolyzed when synthesized independently and that association between the two complementing polypeptides leads to a more stable, catalytically active complex

  8. Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc oligomers and N,N-diacetyllactosamine (LacDiNAc based on galactose oxidase treatment

    Directory of Open Access Journals (Sweden)

    Christiane E. Kupper

    2012-05-01

    Full Text Available The importance of glycans in biological systems is highlighted by their various functions in physiological and pathological processes. Many glycan epitopes on glycoproteins and glycolipids are based on N-acetyllactosamine units (LacNAc; Galβ1,4GlcNAc and often present on extended poly-LacNAc glycans ([Galβ1,4GlcNAc]n. Poly-LacNAc itself has been identified as a binding motif of galectins, an important class of lectins with functions in immune response and tumorigenesis. Therefore, the synthesis of natural and modified poly-LacNAc glycans is of specific interest for binding studies with galectins as well as for studies of their possible therapeutic applications. We present the oxidation by galactose oxidase and subsequent chemical or enzymatic modification of terminal galactose and N-acetylgalactosamine residues of poly-N-acetyllactosamine (poly-LacNAc oligomers and N,N-diacetyllactosamine (LacDiNAc by galactose oxidase. Product formation starting from different poly-LacNAc oligomers was characterised and optimised regarding formation of the C6-aldo product. Further modification of the aldehyde containing glycans, either by chemical conversion or enzymatic elongation, was established. Base-catalysed β-elimination, coupling of biotin–hydrazide with subsequent reduction to the corresponding hydrazine linkage, and coupling by reductive amination to an amino-functionalised poly-LacNAc oligomer were performed and the products characterised by LC–MS and NMR analysis. Remarkably, elongation of terminally oxidised poly-LacNAc glycans by β3GlcNAc- and β4Gal-transferase was also successful. In this way, a set of novel, modified poly-LacNAc oligomers containing terminally and/or internally modified galactose residues were obtained, which can be used for binding studies and various other applications.

  9. Spatial and Temporal Variations in Diatoms from la Chaine des Lacs Urban Watershed, Nord-Pas France, in Relation to Water Quality

    Science.gov (United States)

    Noble, P. J.; Van de Vijver, B.; Verleyen, E.; Prygiel, J.; Ivanovsky, A.; Lesven, L.; Billon, G.

    2016-12-01

    Diatom analysis was conducted on lake sediments in la Chaîne des Lacs (CDL), a shallow eutrophic urban park and storm control system in Villeneuve d'Ascq, France, to address both the present day water quality, and the evolution of this urban system over its 40 year history. The main lake, Lac du Héron (LDH), received recent attention because of water quality problems, including eutrophication, harmful algal blooms, and invasion by the macrophyte Elodea in 2012. A total of 17 sites were collected in CDL, 11 of which were in LDH, to document spatial variability, and a 26cm long core addresses historical changes. The bulk of the diatom assemblage in LDH can be classified as both eutrophic and moderately metal tolerant, using modern national diatom indices developed and used by the French regional water agencies. Surface sediment samples within LDH show large spatial variations in %Cocconeis placentula whose habitat is epiphytic growth on Elodea. Other variation is reflected in the phytoplankton composition both spatially, and interannually. Aulacoseira muzzanensis and Cyclostephanos dubius showed greater abundance in the open water habitats in LDH, whereas sites in CDL outside of LDH had greater Cyclotella meneghiniana. Temporally, Stephanodicsus (largely S. hantzschii), the dominant diatom in early spring, were present in greater abundances in the 2016 surface sediment samples than in any of the 2015 samples. One possible explanation is that the 2016 samples, taken March 30th, preferentially preserved the early spring Stephanodiscus bloom, in contrast to the 2015 samples, which were taken in January. The sediment core provides an historical record, where the uppermost 4cm plot with the bulk of the LDH surface samples and contain abundant Cocconeis, 4 -14cm is phytoplankton-rich, largely Cyclostephanos dubius and Aulacoseira muzzanensis, and represents a less weed-choked environment prior to the 2012 Elodea invasion. The base of the core is dominated by Amphora and

  10. Les carbonates néogènes de Sainte Croix (Iles Vierges). Etude stratigraphique et pétrophysique Neogene Carbonates At Saint Croix, Virgin Islands. Stratigraphic and Petrophysical Study

    OpenAIRE

    Andreieff P.; Mascle A.; Mathieu Y.; Muller C.

    2006-01-01

    Un échantillonnage systématique des principaux affleurements des séries carbonatées néogènes de Sainte Croix (Iles Vierges) a permis de préciser leur extension stratigraphique. C'est ainsi que la section-type de la formation Kingshill, qui avait été récemment attribuée au Miocène supérieur, est désormais datée du Miocène moyen d'après son riche contenu faunistique en foraminifères planctoniques et nannofossiles calcaires. Les diverses mesures pétrophysiques effectuées dans des niveaux d'envir...

  11. Review: Kandungan Mannan pada Tanaman Iles-iles (Amorphophallus muelleri Blume.

    Directory of Open Access Journals (Sweden)

    SUMARWOTO

    2007-05-01

    Full Text Available Mannan is a kind of polysaccharide that shaped from mannose and glucose with molar ratio 3:2. Sum of total mannan have a variation rate, influenced by the age, kind of plant, beginning treatment before drying and many other reason. This kind of carbohydrate is important for the plant, it self, and for human, it can be used for many industries. This polysaccharide produced most by a tuber like iles-iles (Amorphophallus muelleri Blume. mannan polymer has a special character which have an attitude between cellulose and galactomannan, so have and ability to crystallize and shaping soft patterns. Besides Amorphophallus, mannan can be found in a small number of another plant, like Ivory nut, and some of Orchidaceae and some in subdivision Gymnosperm. The way to isolate can be in physically and chemically. And the benefits are for the development of many industries, like food, medical, paper, laboratory, etc.

  12. Paramètres de reproduction des vaches Kouri au Lac Tchad

    African Journals Online (AJOL)

    SARAH

    30 juin 2015 ... Les performances de reproduction de la vache Kouri ont été: l'âge au premier vêlage de 41,43 ± 0,66 mois (n=70) ..... types, même si 14% des femelles ont un rapport ≤1 an. ..... d'organisation et d'orientation de l'élevage au.

  13. The business of refractive laser assisted cataract surgery (ReLACS).

    Science.gov (United States)

    Berdahl, John P; Jensen, Matthew P

    2014-01-01

    Refractive Laser Assisted Cataract Surgery (ReLACS) combines the femtosecond laser with other noncovered tests and services in an attempt to reduce spectacle dependence in combination with cataract surgery. Significant interest is present among ophthalmologists who are considering adopting this technology, however significant capital outlays and continuing expenses can make the decision to adopt ReLACS foreboding. We review the financial considerations of ReLACS and review the trends seen in early adopters of this technology. Recent findings have shown that ReLACS is a growing segment of cataract surgery. Most practices who have implemented the technology have broken even and have a positive outlook on the financial return of implementing the ReLACS program. The average break-even analysis point for practices is around 230 cases a year. ReLACS is growing and appears to be a financial viable approach for many practices.

  14. Adsorption Properties of Lac Dyes on Wool, Silk, and Nylon

    Directory of Open Access Journals (Sweden)

    Bo Wei

    2013-01-01

    Full Text Available There has been growing interest in the dyeing of textiles with natural dyes. The research about the adsorption properties of natural dyes can help to understand their adsorption mechanism and to control their dyeing process. This study is concerned with the kinetics and isotherms of adsorption of lac dyes on wool, silk, and nylon fibers. It was found that the adsorption kinetics of lac dyes on the three fibers followed the pseudosecond-order kinetic model, and the adsorption rate of lac dyes was the fastest for silk and the slowest for wool. The activation energies for the adsorption process on wool, silk, and nylon were found to be 107.15, 87.85, and 45.31 kJ/mol, respectively. The adsorption of lac dyes on the three fibers followed the Langmuir mechanism, indicating that the electrostatic interactions between lac dyes and those fibers occurred. The saturation values for lac adsorption on the three fibers decreased in the order of wool > silk > nylon; the Langmuir affinity constant of lac adsorption on nylon was much higher than those on wool and silk.

  15. An integrated palaeoenvironmental investigation of a 6200 year old peat sequence from Ile de la Possession, Iles Crozet, sub-Antarctica

    NARCIS (Netherlands)

    Van der Putten, N.; Hébrard, J. P.; Verbruggen, C.; Van de Vijver, B.; Disnar, J. R.; Spassov, S.; de Beaulieu, J. L.; De Dapper, M.; Keravis, D.; Hus, J.; Thouveny, N.; Frenot, Y.

    2008-01-01

    A 6200 year old peat sequence, cored in a volcanic crater on the sub-Antarctic Ile de la Possession (Iles Crozet), has been investigated, based on a multi-proxy approach. The methods applied are macrobotanical (mosses, seeds and fruits) and diatom analyses, complemented by geochemical (Rock-Eval6)

  16. Endocrinair : contamination de l'air ambiant : Contamination de l’air ambiant par les perturbateurs endocriniens en Ile de France et caractérisation d’effets toxiques associés

    OpenAIRE

    Chevreuil , Marc; Oziol , Lucie

    2012-01-01

    National audience; En Ile de France, la contamination permanente de l’air ambiant soulève de nouvelles interrogations quant à l’exposition de l’Homme à des perturbateurs endocriniens par cette voie et à la possibilité d’effets sur sa santé, même si ceux-ci sont à faible concentration (micropolluants). Ce qui constitue l’aspect innovant de ce programme, c’est la recherche de molécules semi-volatiles à l’état gazeux ou liées à des particules à l’extérieur et à l’intérieur de locaux (appartement...

  17. Broad band energy distribution of UV-bright BL Lac objects

    International Nuclear Information System (INIS)

    Maraschi, L.; Tanzi, E.G.; Treves, A.

    1984-01-01

    IUE satellite data in the 1200-2000 and 1900-3200 A intervals of BL Lac objects are analyzed in terms of two discernible groups. A total of 25 BL Lac objects were observed, with differences between groups displayed in terms of the power slope of the energy of the UV emissions, i.e., slopes of 1 and 2. Comparisons of the spectra with those of quasars showed that quasars have a small spectral index in the 1000-6000 A band and no correlation exists between the spectral index and UV flux of the BL Lac objects. The comparisons underscore the lack of a thermal component for BL Lac objects. Steep spectral components in both BL Lac objects and highly polarized quasars emissions could both be due to synchrotron emission. Compton scattering of relativistic electrons off synchrotron photons could produce the X ray emissions. 44 references

  18. Broad band energy distribution of UV-bright BL Lac objects

    Energy Technology Data Exchange (ETDEWEB)

    Maraschi, L.; Tanzi, E.G.; Treves, A.

    1984-01-01

    IUE satellite data in the 1200-2000 and 1900-3200 A intervals of BL Lac objects are analyzed in terms of two discernible groups. A total of 25 BL Lac objects were observed, with differences between groups displayed in terms of the power slope of the energy of the UV emissions, i.e., slopes of 1 and 2. Comparisons of the spectra with those of quasars showed that quasars have a small spectral index in the 1000-6000 A band and no correlation exists between the spectral index and UV flux of the BL Lac objects. The comparisons underscore the lack of a thermal component for BL Lac objects. Steep spectral components in both BL Lac objects and highly polarized quasars emissions could both be due to synchrotron emission. Compton scattering of relativistic electrons off synchrotron photons could produce the X ray emissions. 44 references.

  19. Infrared polarimetry and photometry of BL Lac objects. 3

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, P A; Brand, P W.J.L. [Edinburgh Univ. (UK). Dept. of Astronomy; Impey, C D [Hawaii Univ., Honolulu (USA). Inst. for Astronomy; Williams, P M [UKIRT, Hilo, HI (USA)

    1984-10-15

    The data presented here is part of a continuing monitoring programme of BL lac objects with J, H and K photometry and polarimetry. A total of 30 BL Lac objects have now been observed photometrically. Infrared polarimetry has also been obtained for 24 of these objects. The sample is sufficiently large to examine statistically, and several important correlations have emerged. Internight variations and wavelength dependence of polarization indicate that BL Lac objects, as a class, may be understood in terms of a relatively simple two-component model.

  20. The comparison between LAC and ALA

    Directory of Open Access Journals (Sweden)

    Tzu-heng Chiu

    2000-12-01

    Full Text Available A good library association serves its members, improves the librarianship, and helps library institutions achieving their missions. This article describes the history, missions and goals, organization structure, membership, financial sources, professional activities, publication, and website of the Library Association of China (LAC and American Library Association (ALA, respectively. Considering social / cultural / political differences between Taiwan and the United Sates, the author then compares these two library associations from the eight factors mentioned above. At the end, suggestions for the LAC are proposed.[Article content in Chinese

  1. Clustering environments of BL Lac objects

    Science.gov (United States)

    Wurtz, Ronald; Ellingson, Erica; Stocke, John T.; Yee, H. K. C.

    1993-01-01

    We report measurements of the amplitude of the BL Lac galaxy spatial covariance function, B(gb), for the fields of five BL Lacertae objects. We present evidence for rich clusters around MS 1207+39 and MS 1407+59, and confirm high richness for the cluster containing H0414+009. We discuss the ease of 3C 66 A and find evidence for a poor cluster based on an uncertain redshift of z = 0.444. These data suggest that at least some BL Lac objects are consistent with being FR 1 radio galaxies in rich clusters.

  2. Louisiana SIP: LAC 33:III Ch. 7 - Table 2 - Ambient Air--Methods of Contaminant Measurements; SIP effective 1989-05-08 (LAc49) and 1989-08-14 (LAc50) to 2011-08-03 (LAd34 - Moved to Section 711 and revised [adds PM-2.5])

    Science.gov (United States)

    Louisiana SIP: LAC 33:III Ch. 7 - Table 2 - Ambient Air--Methods of Contaminant Measurements; SIP effective 1989-05-08 (LAc49) and 1989-08-14 (LAc50) to 2011-08-03 (LAd34 - Moved to Section 711 and revised [adds PM-2.5])

  3. Gene-mutation assays in lambda-lacZ transgenic mice : comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium

    NARCIS (Netherlands)

    Delft, J.H.M. van; Bergmans, A.; Dam, F.J. van; Tates, A.D.; Howard, L.; Winton, D.J.; Baan, R.A.

    1998-01-01

    Comparison of results derived from transgenic animal gene-mutation assays with those from mutation analyses in endogenous genes is an important step in the validation of the former. We have used λlacZ transgenic mice to study alkylation-induced mutagenesis in vivo in (a) lacZ and hprt in spleen

  4. Induction of the lac carrier and an associated membrane protein in Escherichia coli

    International Nuclear Information System (INIS)

    Lagarias, D.M.

    1985-01-01

    Induction of the lac operon in wild type Escherichia coli strains results in synthesis of a 16 kilodalton inner membrane protein in addition to the known products of the lacZ, lacY and lacA genes. Cells carrying the lacY gene on a plasmid over produce this 16 kilodalton polypeptide as well as the Lac carrier, the membrane protein product of the lacY gene. However, [ 35 S]methionine labeling of minicells carrying the lacY plasmid shows that the 16 kDa protein is not synthesized from the plasmid DNA. The 16 kDa protein was purified and partially characterized. It is an acidic membrane protein of apparent molecular weight 15,800 whose amino terminal sequence (NH 2 -Met-Arg-Asn-Phe-Asp-Leu-) does not correspond to any nucleotide sequence known in lac operon DNA. Using antibody prepared to the purified 16 kDa protein, a quantitative analysis of conditions under which this protein is made was accomplished, and reveals that the amount of 16 kDa protein which appears in the membrane is proportional to lac operon expression. Hybridization of a synthetic oligonucleotide probe complementary to the 5' end of 16 kDa protein mRNA shows that its synthesis is regulated at the level of transcription. A description of attempts to clone this gene is given. Possible functional roles for the 16 kDa protein are discussed

  5. Opening Up Natural Resource Based Industries for Innovation (LAC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Opening Up Natural Resource Based Industries for Innovation (LAC). Commodities based on natural resources account for at least half of the exports of two-thirds of the countries in Latin America and the Caribbean (LAC). There is growing concern, however, that existing natural resource-based industries are ...

  6. Evolutionary behaviour of AGN: Investigations on BL Lac objects and Seyfert II galaxies

    Science.gov (United States)

    Beckmann, V.

    2000-12-01

    The evolution and nature of AGN is still one of the enigmatic questions in astrophysics. While large and complete Quasar samples are available, special classes of AGN, like BL Lac objects and Seyfert II galaxies, are still rare objects. In this work I present two new AGN samples. The first one is the HRX-BL Lac survey, resulting in a sample of X-ray selected BL Lac objects. This sample results from 223 BL Lac candidates based on a correlation of X-ray sources with radio sources. The identification of this sample is 98% complete. 77 objects have been identified as BL Lac objects and form the HRX-BL Lac complete sample, the largest homogeneous sample of BL Lac objects existing today. For this sample, redshifts are now known for 62 objects (81 %). In total I present 101 BL Lac objects in the enlarged HRX-BL Lac survey, for which redshift information is available for 84 objects. During the HRX-BL Lac survey I found several objects of special interest. 1ES 1517+656 turned out to be the brightest known BL Lac object in the universe. 1ES 0927+500 could be the first BL Lac object with a line detected in the X-ray region. RX J1211+2242 is probably the the counterpart of the up to now unidentified gamma-ray source 3EG J1212+2304. Additionally I present seven candidates for ultra high frequency peaked BL Lac objects. RX J1054+3855 and RX J1153+3517 are rare high redshift X-ray bright QSO or accreting binary systems with huge magnetic fields. For the BL Lac objects I suggest an unified scenario in which giant elliptical galaxies, formed by merging events of spiral galaxies at z > 2, start as powerful, radio dominated BL Lacs. As the jet gets less powerful, the BL Lacs start to get more X-ray dominated, showing less total luminosities (for z definition to objects with a calcium break up to 40%, but do not support for the HBL the idea of allowing emission lines in the spectra of BL Lac galaxies. A way to find high redshift BL Lac objects might be the identification of faint X

  7. 115-IJBCS-Article-Dr Montchowui

    African Journals Online (AJOL)

    RHUMSIKI

    Cette étude concerne l'un des petits lacs du sud Bénin : le lac Hlan. Elle vise à faire l'inventaire de l'ichtyofaune et à déterminer l'organisation des peuplements de poissons du lac. L'ichtyofaune a été ... l'accroissement des performances des engins de pêche utilisés ... humide du type soudano-guinéen du Nord. Bénin.

  8. DYNAMIQUE DES PEUPLEMENTS DE POISSONS DANS LE RÉSERVOIR DE PETIT-SAUT (FLEUVE SINNAMARY, GUYANE FRANÇAISE.

    Directory of Open Access Journals (Sweden)

    DE MÉRONA B.

    2002-01-01

    Full Text Available La modélisation des effets des barrages hydroélectriques nécessite un grand nombre de données d’observation dans chacune des situations concrètes. En zone tropicale ces données sont souvent incomplètes et de nature hétérogène rendant difficile la comparaison entre des situations différentes. En janvier 1994, Electricité de France (EDF : Compagnie Nationale française d’Electricité a procédé à la fermeture du barrage de Petit-Saut sur le fleuve Sinnamary en Guyane française. A cette occasion, un suivi environnemental a été mené sur une période s’étendant depuis 5 années avant la fermeture jusqu’à 7 années après. En ce qui concerne les poissons, trois phases successives dans le processus de colonisation du lac ont été identifiées. Pendant la phase de mise en eau, les captures de poissons ont rapidement augmenté alors que la richesse spécifique diminuait. Une espèce dominait le peuplement. Durant les 2 années qui ont suivi, les captures se sont maintenues à un niveau élevé alors que la richesse spécifique continuait à diminuer. Le peuplement était dominé par deux espèces capables de tirer avantage des nouvelles ressources offertes par le lac. Enfin, au cours des 4 années suivantes, les captures diminuaient lentement et régulièrement et la composition spécifique se modifiait profondément. Ce schéma semble conforme à ce qui a été observé dans plusieurs grandes retenues en zone tropicale.

  9. Evidence for an intermediate conformational state of LacY.

    Science.gov (United States)

    Jiang, Xiaoxu; Guan, Lan; Zhou, Yonggang; Hong, Wen-Xu; Zhang, Qinghai; Kaback, H Ronald

    2012-03-20

    LacY mutant Cys154 → Gly exhibits a periplasmic-closed crystal structure identical to the WT, but is periplasmic-open in the membrane. The mutant hardly catalyzes transport, but binds galactosides from either side of the membrane with the same affinity and is resistant to site-directed proteolysis relative to the pseudo-WT. Site-directed alkylation was also applied to 11 single-Cys mutants in Cys154 → Gly LacY in right-side-out membrane vesicles or after solubilization and purification in dodecyl-β-D-maltopyranoside (DDM). Unlike the pseudo-WT, Cys replacements on the periplasmic side of the Cys154 → Gly mutant label rapidly in the membrane without sugar, but labeling decreases markedly after the mutant proteins are purified. Thus, Cys154 → Gly LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. Notably, branched-chain or neopentyl glycol maltoside detergents stabilize Cys154 → Gly LacY in the membrane-embedded form.

  10. The use of lac-type promoters in control analysis

    DEFF Research Database (Denmark)

    Jensen, Peter Ruhdal; Westerhoff, H. v.; Michelsen, Ole

    1993-01-01

    experimentally by constructing E. coli strains, in which the chromosomal atp operon is transcribed from the lacUV5 and the tacI promoter. We measured the concentration of the c subunit of H+-ATPase, and found that the expression of this enzyme could be modulated between non-detectable levels and up to five times...... the wild-type level. Thus, in the absence of inducer, no expression of atp genes could be detected when the atp operon was controlled by the lacUV5 promoter, and we estimate that the expression was less than 0.0025 times the wild-type level. We show that the introduction of a lac Y mutation facilitated...

  11. Physico-Mechanical Properties of Coprocessed Excipient MicroceLac® 100 by DM(3) Approach.

    Science.gov (United States)

    Haware, Rahul V; Kancharla, Joseph P; Udupa, Aishwarya K; Staton, Scott; Gupta, Mali R; Al-Achi, Antoine; Stagner, William C

    2015-11-01

    To determine the effect of relative humidity (RH) and hydroxypropyl methylcellulose (HPMC) on the physico-mechanical properties of coprocessed MacroceLac(®) 100 using 'DM(3)' approach. Effects of RH and 5% w/w HPMC on MacroceLac(®) 100 Compressibility Index (CI) and tablet mechanical strength (TMS) were evaluated by 'DM(3)'. The 'DM(3)' approach evaluates material properties by combining 'design of experiments', material's 'macroscopic' properties, 'molecular' properties, and 'multivariate analysis' tools. A 4X4 full-factorial experimental design was used to study the relationship of MacroceLac(®) 100 molecular properties (moisture content, dehydration, crystallization, fusion enthalpy, and moisture uptake) and macroscopic particle size and shape on CI and TMS. A physical binary mixture (PBM) of similar composition to MacroceLac(®) 100 was also evaluated. Multivariate analysis of variance (MANOVA), principle component analysis, and partial least squares (PLS) were used to analyze the data. MANOVA CI ranking was: PBM-HPMC > PBM > MicroceLac(®)100 > MicroceLac(®)100-HPMC (p TMS values were lower than MicroceLac(®)100 and MicroceLac(®)100-HPMC (p TMS. Significant MicroceLac(®)100 changes occurred with % RH exposure affecting performance attributes. HPMC physical addition did not prevent molecular or macroscopic matrix changes.

  12. Solving a discrete model of the lac operon using Z3

    Science.gov (United States)

    Gutierrez, Natalia A.

    2014-05-01

    A discrete model for the Lcac Operon is solved using the SMT-solver Z3. Traditionally the Lac Operon is formulated in a continuous math model. This model is a system of ordinary differential equations. Here, it was considerated as a discrete model, based on a Boolean red. The biological problem of Lac Operon is enunciated as a problem of Boolean satisfiability, and it is solved using an STM-solver named Z3. Z3 is a powerful solver that allows understanding the basic dynamic of the Lac Operon in an easier and more efficient way. The multi-stability of the Lac Operon can be easily computed with Z3. The code that solves the Boolean red can be written in Python language or SMT-Lib language. Both languages were used in local version of the program as online version of Z3. For future investigations it is proposed to solve the Boolean red of Lac Operon using others SMT-solvers as cvc4, alt-ergo, mathsat and yices.

  13. Infrared polarimetry and photometry of BL Lac objects

    Energy Technology Data Exchange (ETDEWEB)

    Impey, C D; Brand, P W.J.L. [Edinburgh Univ. (UK); Wolstencroft, R D; Williams, P M [Royal Observatory, Edinburgh (UK)

    1982-07-01

    Infrared polarimetry and photometry have been obtained for a sample of 18 BL Lac objects. The data covers a period of one year and is part of a continuing monitoring programme; all observations were in the J,H and K wavebands. Large and variable degrees of polarization are a common property of the sample. Two BL Lac objects show wavelength-dependent polarization, with the polarization increasing towards shorter wavelengths, and two objects show evidence for position angle rotations over a five-day period. The relationship between changes in polarized and total flux is also discussed. The BL Lac objects cover an enormous range of infrared luminosity; the three most luminous having Lsub(IR) > 10/sup 46/ erg s/sup -1/ and the other end of the range having infrared luminosities similar to normal elliptical galaxies. These are the first published infrared polarimetric observations for eight of the sample.

  14. Beware of your Cre-Ation: lacZ expression impairs neuronal integrity and hippocampus-dependent memory.

    Science.gov (United States)

    Reichel, J M; Bedenk, B T; Gassen, N C; Hafner, K; Bura, S A; Almeida-Correa, S; Genewsky, A; Dedic, N; Giesert, F; Agarwal, A; Nave, K-A; Rein, T; Czisch, M; Deussing, J M; Wotjak, C T

    2016-10-01

    Expression of the lacZ-sequence is a widely used reporter-tool to assess the transgenic and/or transfection efficacy of a target gene in mice. Once activated, lacZ is permanently expressed. However, protein accumulation is one of the hallmarks of neurodegenerative diseases. Furthermore, the protein product of the bacterial lacZ gene is ß-galactosidase, an analog to the mammalian senescence-associated ß-galactosidase, a molecular marker for aging. Therefore we studied the behavioral, structural and molecular consequences of lacZ expression in distinct neuronal sub-populations. lacZ expression in cortical glutamatergic neurons resulted in severe impairments in hippocampus-dependent memory accompanied by marked structural alterations throughout the CNS. In contrast, GFP expression or the expression of the ChR2/YFP fusion product in the same cell populations did not result in either cognitive or structural deficits. GABAergic lacZ expression caused significantly decreased hyper-arousal and mild cognitive deficits. Attenuated structural and behavioral consequences of lacZ expression could also be induced in adulthood, and lacZ transfection in neuronal cell cultures significantly decreased their viability. Our findings provide a strong caveat against the use of lacZ reporter mice for phenotyping studies and point to a particular sensitivity of the hippocampus formation to detrimental consequences of lacZ expression. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  15. Optical Spectra Evolution of BL Lac Objects XW Bi1,∗ , BZ Wang2

    Indian Academy of Sciences (India)

    low-frequency peaked BL Lac objects (LBLs) is steeper than the high- frequency peaked BL Lac ... vision of BL Lac objects. Many investigators .... We are grateful to the Scientific Research Foundation of the Education Department of Yunnan ...

  16. Flat radio-spectrum galaxies and BL Lacs I. Core properties

    NARCIS (Netherlands)

    Dennett-Thorpe, J; Marcha, MJ

    This paper concerns the relationship of BL Lacs and flat-spectrum weak emission-line galaxies. We compare the weak emission-line galaxies and the BL Lacs in a sample of 57 flat-spectrum objects (Marcha et al. 1996), using high-frequency radio and non-thermal optical flux densities, spectral indices

  17. Présence de trois espèces de grégarines (Apicomplexa : Eugregarinorida chez l’Annélide Polychete Marphysa sanguinea (Montagu, 1815 dans le lac de Tunis

    Directory of Open Access Journals (Sweden)

    Elbarhoumi M.

    2010-03-01

    Full Text Available Trois espèces de grégarines ont été trouvées dans des spécimens de l’annélide polychète Marphysa sanguinea récoltés dans le lac de Tunis : Bhatiella marphysae Setna, 1931, parasite de Marphysa sanguinea (Inde, Europe; Ferraria cornucephala iwamusi H. Hoshide, 1956, parasite de Marphysa iwamusi (Japon ; et Viviera sp. qui présente des similitudes avec Viviera marphysae Schrével, 1963, aussi décrite chez Marphysa sanguinea (France. Ces grégarines sont rapportées pour la première fois chez ce dernier hôte en Tunisie. Bhatiella marphysae et Viviera sp. appartiennent à la famille des Lecudinidae (Aseptatorina. La présence d’un septum proto-deutoméritique est confirmée chez Ferraria cornucephala qui doit être maintenue dans les Polyrhabdinae.

  18. Lysines 72, 80 and 213 and aspartic acid 210 of the Lactococcus lactis LacR repressor are involved in the response to the inducer tagatose-6-phosphate leading to induction of lac operon expression.

    Science.gov (United States)

    van Rooijen, R J; Dechering, K J; Niek, C; Wilmink, J; de Vos, W M

    1993-02-01

    Site-directed mutagenesis of the Lactococcus lactis lacR gene was performed to identify residues in the LacR repressor that are involved in the induction of lacABCDFEGX operon expression by tagatose-6-phosphate. A putative inducer binding domain located near the C-terminus was previously postulated based on homology studies with the Escherichia coli DeoR family of repressors, which all have a phosphorylated sugar as inducer. Residues within this domain and lysine residues that are charge conserved in the DeoR family were changed into alanine or arginine. The production of the LacR mutants K72A, K80A, K80R, D210A, K213A and K213R in the LacR-deficient L.lactis strain NZ3015 resulted in repressed phospho-beta-galactosidase (LacG) activities and decreased growth rates on lactose. Gel mobility shift assays showed that the complex between a DNA fragment carrying the lac operators and LacR mutants K72A, K80A, K213A and D210A did not dissociate in the presence of tagatose-6-phosphate, in contrast to wild type LacR. Other mutations (K62A/K63A, K72R, K73A, K73R, T212A, F214R, R216R and R216K) exhibited no gross effects on inducer response. The results strongly suggest that the lysines at positions 72, 80 and 213 and aspartic acid at position 210 are involved in the induction of lac operon expression by tagatose-6-phosphate.

  19. Comprendre les obstacles à la paix dans la région des Grands Lacs ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Nouveau webinaire IWRA/CRDI sur les changements climatiques et la gestion adaptive de l'eau. L'Association internationale de ressources en eau (IWRA), en étroite collaboration avec le CRDI, organise un webinaire intitulé "Changements climatiques et gestion adaptive de l'eau: des... Voir davantageNouveau webinaire ...

  20. Baseline surveys of Lac Bay benthic and fish communities, Bonaire

    NARCIS (Netherlands)

    Debrot, A.O.; Hylkema, A.; Vogelaar, W.; Meesters, H.W.G.; Engel, M.S.; Leon, R.; Prud'homme van Reine, W.F.; Nagelkerken, I.

    2012-01-01

    Lac Bay is a clear-water, 5 m deep shallow tropical lagoon of 7 km2 opening onto the wave and wind exposed east coast of the island of Bonaire, southern Caribbean. Over the last decades land reclamation by mangroves in Lac has been expanding the surface of turbid, saline backwaters into the bay at

  1. The REX survey as a Tool to Test the Beaming Model for BL Lacs

    Science.gov (United States)

    Caccianiga, A.; della Ceca, R.; Gioia, I. M.; Maccacaro, T.; Wolter, A.

    We present the preliminary properties of the BL Lacs discovered in the REX survey (Caccianiga et al. 1998). In particular, we discuss a few sources with optical spectral properties ``intermediate'' between those of BL Lacs and those of elliptical galaxies. These objects could harbour weak (in the optical band) sources of non-thermal continuum in their nuclei and, if confirmed, they could represent the faint tail of the BL Lac population. The existence of such ``weak'' BL Lacs is matter of discussion in recent literature (e.g. Marcha et al. 1996) and could lead to a revision of the defining criteria of a BL Lac and, consequently, of their cosmological and statistical properties.

  2. Energies in Ile de France - state of the art

    International Nuclear Information System (INIS)

    2003-01-01

    Because of the area of Ile de France, depends for 94% of outside for its energy needs, a local energy policy is a priority for the region. This document provides recommendations for the next SDRIF (Directory Scheme for the Ile De France Region) publication. After a recall of some definitions, it presents the main characteristics of the regional energy production and of the consumption. In the next chapters it analyses the final regional energy consumption per energy types and per economic activities sector and presents the organization of the energy supply of the region. Five domains of thought complete this analysis by an evaluation of the next energy policy approach: the tomorrow energy needs, the energy supply security, the place of the renewable energies in Ile de France, the transports problem, the minimization of the natural, industrial and social risks. (A.L.B.)

  3. The Radio-optical Spectra of BL Lacs and Possible Relatives

    Science.gov (United States)

    Dennett-Thorpe, J.

    I consider the suggestion that, in a complete sample of flat-spectrum radio sources with available optical spectra (Marcha et al 1996), the strong emission line objects, or those with passive elliptical spectra are close relatives of the BL Lacs. New observations at four frequencies from 8 to 43GHz are presented, together with evidence for radio variability. Combined with other radio and optical data from the literature, we are able to construct the non-thermal SEDs and use these to address the questions: are the optically passive objects potentially `unrecognised' BL Lacs (either intrinsically weak and/or hidden by starlight)? What is the relationship between the surprising number of strong emission-line objects and the BL Lacs?

  4. Penis Ödemi ile Kendini Gösteren Henoch-Schönlein Purpurası

    OpenAIRE

    UZUN, Hakan; ALAGÖZ, Demet; ?ENSES, Dursun Ali; D?K?C?, Bünyamin; KOCABAY, Kenan

    2015-01-01

    Henoch Schonlein purpurası artrit/artralji, gastrointestinal sistem ve renal tutulumun e?lik etti?i nontrombositopenik purpura ile karakterize bir sendromdur. Burada penis ödemi ile ba?vuran 3 ya??ndaki bir erkek hasta sunulmuştur. Bu ?ekilde nadir olan bağlangıç bulguları nedeni ile Henoch Schonlein purpurası tanıs?nda zorluk çekilebilmektedir.

  5. Les porphyres Luganois et leurs enveloppes. L’histoire géologique des Alpes Tessinoises entre Lugano et Varese

    NARCIS (Netherlands)

    Sitter, de L.U.

    1939-01-01

    Serrant de près le lac de Lugano, se trouve un vieux pays volcanique, environné de montagnes calcaires escarpées, qui, malgré son peu d'étendue a une histoire géologique des plus intéressantes. Les laves et les tufs de ces volcans anciens sont d’une grande diversité et ont fourni en ces derniers

  6. Characterization of atmospheric aerosols in Ile-de-France: Local contribution and Long range transport; Caracteisation des aeosols atmospheiques en Ile-de-France: contribution locale et transport a longues distances

    Energy Technology Data Exchange (ETDEWEB)

    Cuesta, J.E

    2006-06-15

    Atmospheric aerosols interact directly in a great number of processes related to climate change and public health, modifying the energy budget and partly determining the quality of the air we breathe. In my PhD, I chose to study the perturbation, if not the aggravation, of the living conditions in Ile-de-France associated to aerosol transport episodes in the free troposphere. This situation is rather frequent and still badly known. To achieve my study, I developed the observation platform 'TReSS' Transportable Remote Sensing Station, whose instruments were developed at the Laboratoire de Meteorology Dynamique by the LiMAG team. 'TReSS' consists of a new high-performance 'Mini-Lidar' and of two standard radiometers: a sun photometer and a thermal infrared radiometer. The principle of my experimental approach is the synergy of the vertical Lidar profiles and the particle size distributions over the column, obtained by the 'Almucantar' inversion of sun photometer data. The new 'Lidar and Almucantar' method characterizes the vertical distribution by layer and the optical micro-physical properties of the local and transported aerosols. Firstly, I undertook the characterization of the Paris aerosol, mainly of anthropogenic origin. Their radiative properties were analyzed in the daily and yearly scales. Then, I conducted a statistical multi-year study of transport episodes and a two-week study case, representative of a succession of desert dust intrusion in Ile-de-France. My PhD work concludes by a study on the impact of biomass burning aerosols during the heat wave on August 2003. I study the impact of the transported aerosols into the local radiative budget and the possible consequences on the diurnal cycle of the atmospheric boundary layer. (author)

  7. RADIO-WEAK BL LAC OBJECTS IN THE FERMI ERA

    Energy Technology Data Exchange (ETDEWEB)

    Massaro, F.; Marchesini, E. J. [Dipartimento di Fisica, Università degli Studi di Torino (UniTO), via Pietro Giuria 1, I-10125 Torino (Italy); D’Abrusco, R.; Smith, Howard A. [Smithsonian Astrophysical Observatory, 60 Garden Street, 02138 Cambridge, MA (United States); Masetti, N. [INAF—Istituto di Astrofisica Spaziale e Fisica Cosmica di Bologna, via Gobetti 101, I-40129, Bologna (Italy); Andruchow, I. [Facultad de Ciencias Astronómicas y Geofísicas, Universidad Nacional de La Plata, Paseo del Bosque, B1900FWA, La Plata (Argentina)

    2017-01-10

    The existence of “radio-weak BL Lac objects” (RWBLs) has been an open question, and has remained unsolved since the discovery that quasars could be radio-quiet or radio-loud. Recently, several groups identified RWBL candidates, mostly found while searching for low-energy counterparts of the unidentified or unassociated gamma-ray sources listed in the Fermi catalogs. Confirming RWBLs is a challenging task since they could be confused with white dwarfs (WDs) or weak emission line quasars (WELQs) when there are not sufficient data to precisely draw their broadband spectral energy distribution, and their classification is mainly based on a featureless optical spectra. Motivated by the recent discovery that Fermi BL Lacs appear to have very peculiar mid-IR emission, we show that it is possible to distinguish between WDs, WELQs, and BL Lacs using the [3.4]–[4.6]–[12] μ m color–color plot built using the WISE magnitudes when the optical spectrum is available. On the basis of this analysis, we identify WISE J064459.38+603131 and WISE J141046.00+740511.2 as the first two genuine RWBLs, both potentially associated with Fermi sources. Finally, to strengthen our identification of these objects as true RWBLs, we present multifrequency observations for these two candidates to show that their spectral behavior is indeed consistent with that of the BL Lac population.

  8. RADIO-WEAK BL LAC OBJECTS IN THE FERMI ERA

    International Nuclear Information System (INIS)

    Massaro, F.; Marchesini, E. J.; D’Abrusco, R.; Smith, Howard A.; Masetti, N.; Andruchow, I.

    2017-01-01

    The existence of “radio-weak BL Lac objects” (RWBLs) has been an open question, and has remained unsolved since the discovery that quasars could be radio-quiet or radio-loud. Recently, several groups identified RWBL candidates, mostly found while searching for low-energy counterparts of the unidentified or unassociated gamma-ray sources listed in the Fermi catalogs. Confirming RWBLs is a challenging task since they could be confused with white dwarfs (WDs) or weak emission line quasars (WELQs) when there are not sufficient data to precisely draw their broadband spectral energy distribution, and their classification is mainly based on a featureless optical spectra. Motivated by the recent discovery that Fermi BL Lacs appear to have very peculiar mid-IR emission, we show that it is possible to distinguish between WDs, WELQs, and BL Lacs using the [3.4]–[4.6]–[12] μ m color–color plot built using the WISE magnitudes when the optical spectrum is available. On the basis of this analysis, we identify WISE J064459.38+603131 and WISE J141046.00+740511.2 as the first two genuine RWBLs, both potentially associated with Fermi sources. Finally, to strengthen our identification of these objects as true RWBLs, we present multifrequency observations for these two candidates to show that their spectral behavior is indeed consistent with that of the BL Lac population.

  9. An Eleven Year Review of Failed Female Sterilisation in Ile-Ife, Nigeria

    African Journals Online (AJOL)

    An Eleven Year Review of Failed Female Sterilisation in Ile-Ife, Nigeria. ... Teaching Hospitals Complex, Ile-Ife, Nigeria from October 1 1987 to September 30 1998. ... (Tropical Journal of Obstetrics and Gynaecology, 2001, 18(1): 8-11) ...

  10. Ethanol Production from Non-Food Tubers of Iles-iles (Amorphophallus campanulatus by Using Separated Hydrolysis and Fermentation

    Directory of Open Access Journals (Sweden)

    Kusmiyati Kusmiyati

    2014-07-01

    Full Text Available The decrease in production and the raise in needs have led to the rise in oil prices. This work investigated the possibility of Iles-iles (Amorphophallus campanulatus tuber flour, which is rich in carbohydrate con-tent, as a raw material to produce bioethanol. To obtain the maximum ethanol concentration, several parameters had been studied, such as: the concentration of α-amylase and β-amylase in liquefaction and sac-charification processes, respectively, the type of S. cerevisiae enzyme (pure, dry, wet and instant and weight of Diammonium phosphate (DAP as a nutrient for S. cerevisiae in fermentation. The result shows that the highest reducing sugar content (12.5% was achieved when 3.2 ml α-amylase/kg flour and 6.4 ml β-amylase/kg flour were used during liquefaction and saccharification processes. Since the concentration of α- and β-amylase increased, the reducing sugar obtained also increased. The higher sugar content resulted the higher the ethanol concentration in the fermentation broth. Furthermore, the highest concentration of ethanol (9 %v/v was obtained at 72 h fermentation using the dry S. cerevisiae, at 3.2 ml and 6.4 ml /kg flour of α-amylase and β-amylase enzymes, respectively. From the study of the effect of S. cerevisiae type, it was shown that dry S. cereviseae produced the highest ethanol concentration 10.2% (v/v at 72 h fermentation. The DAP was used as a nitrogen supply required by S. cerevisiae to growth and as a results can increase the ethanol concentration. The addition of DAP in the fermentation proved that 8.45% (v/v of ethanol was obtained. This result shows that the proposed tuber flour has the potential a raw material for bioethanol production. © 2014 BCREC UNDIP. All rights reservedReceived: 7th January 2014; Revised: 10th March 2014; Accepted: 18th March 2014[How to Cite: Kusmiyati, K. (2014. Ethanol Production from Non-Food Tubers of Iles-iles (Amorphophallus campanulatus by using Separated Hydrolysis and

  11. Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

    DEFF Research Database (Denmark)

    Almind, Katrine; Delahaye, Laurent; Hansen, Torben

    2002-01-01

    . When the four human p85alpha proteins were expressed in yeast, a 27% decrease occurred in the level of protein expression of p85alpha(Ile/Asp) (P = 0.03) and a 43% decrease in p85alpha(Ile/Asn) (P = 0.08) as compared with p85alpha(Met/Asp). Both p85alpha(Ile/Asp) and p85alpha(Ile/Asn) also exhibited...... increased binding to phospho-insulin receptor substrate-1 by 41% and 83%, respectively (P substrate-1 slightly increased in brown preadipocytes derived from p85alpha...... knockout mice. Both p85alpha(Met) and p85alpha(Ile) had similar effects on AKT activity and were able to reconstitute differentiation of the preadipocytes, although the triglyceride concentration in fully differentiated adipocytes and insulin-stimulated 2-deoxyglucose uptake were slightly lower than...

  12. Time-dependent inhomogeneous jet models for BL Lac objects

    Science.gov (United States)

    Marlowe, A. T.; Urry, C. M.; George, I. M.

    1992-05-01

    Relativistic beaming can explain many of the observed properties of BL Lac objects (e.g., rapid variability, high polarization, etc.). In particular, the broadband radio through X-ray spectra are well modeled by synchrotron-self Compton emission from an inhomogeneous relativistic jet. We have done a uniform analysis on several BL Lac objects using a simple but plausible inhomogeneous jet model. For all objects, we found that the assumed power-law distribution of the magnetic field and the electron density can be adjusted to match the observed BL Lac spectrum. While such models are typically unconstrained, consideration of spectral variability strongly restricts the allowed parameters, although to date the sampling has generally been too sparse to constrain the current models effectively. We investigate the time evolution of the inhomogeneous jet model for a simple perturbation propagating along the jet. The implications of this time evolution model and its relevance to observed data are discussed.

  13. Crisis in LAC : Infrastructure Investment, Employment and the Expectations of Stimulus

    OpenAIRE

    Schwartz, Jordan; Andres, Luis; Dragoiu, Georgeta

    2009-01-01

    Infrastructure investment is a central part of the stimulus plans of the Latin America and the Caribbean (LAC) region as it confronts the growing financial crisis. This paper estimates the potential effects on direct, indirect, and induced employment for different types of infrastructure projects with LAC-specific variables. The analysis finds that the direct and indirect short-term employ...

  14. lac repressor is an antivirulence factor of Salmonella enterica: its role in the evolution of virulence in Salmonella.

    Directory of Open Access Journals (Sweden)

    Sandeepa M Eswarappa

    Full Text Available The genus Salmonella includes many pathogens of great medical and veterinary importance. Bacteria belonging to this genus are very closely related to those belonging to the genus Escherichia. lacZYA operon and lacI are present in Escherichia coli, but not in Salmonella enterica. It has been proposed that Salmonella has lost lacZYA operon and lacI during evolution. In this study, we have investigated the physiological and evolutionary significance of the absence of lacI in Salmonella enterica. Using murine model of typhoid fever, we show that the expression of LacI causes a remarkable reduction in the virulence of Salmonella enterica. LacI also suppresses the ability of Salmonella enterica to proliferate inside murine macrophages. Microarray analysis revealed that LacI interferes with the expression of virulence genes of Salmonella pathogenicity island 2. This effect was confirmed by RT-PCR and Western blot analysis. Interestingly, we found that SBG0326 of Salmonella bongori is homologous to lacI of Escherichia coli. Salmonella bongori is the only other species of the genus Salmonella and it lacks the virulence genes of Salmonella pathogenicity island 2. Overall, our results demonstrate that LacI is an antivirulence factor of Salmonella enterica and suggest that absence of lacI has facilitated the acquisition of virulence genes of Salmonella pathogenicity island 2 in Salmonella enterica making it a successful systemic pathogen.

  15. In vivo biocompatibility of p(HPMAm-lac)-PEG hydrogels hybridized with hyaluronan

    NARCIS (Netherlands)

    Sabbieti, Maria Giovanna; Dubbini, Alessandra; Laus, Fulvio; Paggi, Emanuele; Marchegiani, Andrea; Capitani, Melania; Marchetti, Luigi; Dini, Fabrizio; Vermonden, Tina; Di Martino, Piera; Agas, Dimitrios; Censi, Roberta

    2017-01-01

    The present study reports on the biocompatibility in vivo after intramuscular and subcutaneous administration in Balb/c mice of vinyl sulphone bearing p(HPMAm-lac1-2)-PEG-p(HPMAm-lac1-2)/thiolated hyaluronic acid hydrogels, designed as novel injectable biomaterials for potential application in the

  16. Can blueshifted Agn spectra explain B L Lac objects

    International Nuclear Information System (INIS)

    Basu, D.

    2009-01-01

    B L Lac spectra are almost completely devoid of any emission line, and absorption features are often present based on which redshifts are estimated. Several models have been proposed to explain the spectra, including the unification scheme currently most popular among astronomers. However, there appear to be ambiguities, uncertainties and contradictory results in this model, and many questions remain unanswered. Also, it involves the process of artificially enhancing the continuum to be concentrated to a high level, by the relativistically beaming jet action, in order to submerge the emission lines, partly or completely, to make them appear weak or invisible. Additionally, the sample based on which B L Lac objects have been included in the unification scheme is rather small to be statistically viable. In this context, we present an alternative and much simpler interpretation of the observed spectra of B L Lac objects, both emission and absorption, as blueshifted lines in Agn. Original spectra of fifty six objects available in the current literature are re-analyzed. Nine of these show only a single weak emission line and no absorption feature, while thirty five exhibit no emission feature but several absorption lines, and another twelve show more than one emission line and, in some cases, several absorption lines. It is demonstrated that emission lines in most B L Lac objects are blueshifted out of the visible region, and, hence, not seen at all. Emission lines, when seen, and absorption lines, are blueshifted and are identified with search lines of longer wavelengths that are naturally weak. Blue shifts, in emission and absorption features, are determined for all objects. Various considerations lead to the conclusion that the blue shift interpretation of B L Lac spectra is superior to and more important than the redshift interpretation. A possible explanation of observed blue shifts is presented in the scenario of the ejection process, a well-recognized mechanism

  17. Multi-Wave Luminosity of High-Synchrotron-Peaked TeV BL Lacs ...

    Indian Academy of Sciences (India)

    LIR, Lγ) in the radio, near-infrared and γ-ray wave bands for HSP. TeV BL Lacs. The results show that there are significant intrinsic cor- relations between LR and Lγ and between LIR and Lγ in all states. (high/average/low), and suggest that for HSP TeV BL Lacs, the Syn- chrotron Self-Compton radiation (SSC) is the main ...

  18. STRUCTURAL ASPECTS REGARDING TO THE IMAGE OF ICE HOTEL BALEA LAC BREND

    Directory of Open Access Journals (Sweden)

    Marian ZAHARIA

    2008-06-01

    Full Text Available Applying a poll-based survey provides important information regarding the tourist offer particulars in Bâlea Lac area. On the day the survey is performed its main advantage is also outlined: the fact that this information display a good accuracy, are obtained in a short time span and involving relatively low expenses. Data collection and centralization of the answers provided by interviewed tourists regarding tourism practice in the Bâlea Lac area have led to drawing up distributions that are presented in the paper. Based on the respective information, statistics methods adequate to the study of tourist opinion on the Bâlea Lac Ice Hotel brand image. Several issues have been outlined, regarding the types of respondents based on their category, Romanian or foreigners, from Romania and based on destination countries, function of: the type of stay; the means of information; their answers referring to their first arrival at Bâlea Lac; the degree of destination assessment; their opinion on host reception; their preference for Bâlea Lac; appreciating value for money; age groups; gender; social and professional standing. The image created through the attractions and services provided in the Bâlea Lac tourist area by tourism activities closely related to the Ice Hotel is well appreciated, so that they have opened up a rather favourable expectancy for those willing to come back and for those tempted to try and spend their holidays in the presented hotel.

  19. De Paris à Lyon. Les mutations éditoriales du «Lancelot du Lac»

    Directory of Open Access Journals (Sweden)

    Gaëlle Burg

    2015-07-01

    Full Text Available Lancelot du Lac est le premier roman arthurien imprimé à la Renais­sance. Dans sa première édition parue en 1488, qui réunit deux imprimeurs (Jean Le Bourgeois à Rouen et Jean Du Pré à Paris, un découpage et un prologue inédits sont ajoutés par le remanieur. Le texte sera réédité six fois par divers imprimeurs-libraires parisiens jusqu’en 1533. L’édition de luxe d’Antoine Vérard (1494, destinée au roi Charles VIII, présente d’importantes modifications effectuées dans un but commercial. Après une longue période d’accalmie qui signe le début du déclin de la vogue des romans de chevalerie médiévaux, Benoît Rigaud publie à Lyon, sous une forme considérablement abrégée, la dernière édition connue du Lancelot au XVIe siècle (1591. Si elle ne présente que peu d’intérêt littéraire, elle apporte cependant des informations concernant les pratiques éditoriales et les goûts du  lecteur de la fin du XVIe siècle. De Paris à Lyon, entre renaissance et déclin, le parcours éditorial d’un incontournable roman arthurien.Lancelot du Lac is the editio princeps of an Arthurian romance in Renaissance France. The first edition in 1488, which brings together two printers (Jean Le Bourgeois from Rouen and Jean Du Pré from Paris, offers original arrangement and prologue added by the compositor. The text will be published six times by various printers and booksellers in Paris until 1533. The luxurious edition from Antoine Vérard (1494 dedicated to King Charles VIII provides interesting transformations in commercial purposes. After a long time without edition, showing the beginning of chivalry literature’s decline, Benoît Rigaud publish in Lyon, in a greatly abbreviated form, the last known edition of Lancelot in the XVIth century (1591. If it presents no literary interest, it provides nevertheless informations about editorial practices and reader’s tastes from the end of Renaissance France. From Paris to

  20. Multi-wavelength studies of TeV γ-ray emitting BL Lac objects

    International Nuclear Information System (INIS)

    Kaufmann, Sarah Sabine

    2012-01-01

    The discovery of TeV γ-ray emission of BL Lac objects gave new insights in the particle acceleration and the emission processes of the highly relativistic jets. To shed light on the conditions in the high energetic jets of the TeV γ-ray emitting BL Lac objects, I have studied in great detail the spectral energy distribution (SED) of sources with different characteristics. BL Lac objects with exceptional very high energy spectra (soft and hard spectra) and with large differences in the emission peak frequencies, to cover the different classes of BL Lac objects, have been chosen. The basic aim of this thesis was, to study with new, simultaneous multi- avelength (MWL) observations, if the emission processes of these extreme cases of TeV BL Lac objects can be explained by the synchrotron Self-Compton (SSC) model which is well established for the class of BL Lac objects at lower energies. We proposed MWL observations in the optical, UV and X-ray regime, to be conducted simultaneous to very high energy observations with the H.E.S.S. experiment, to study the emission processes. Simultaneous observations are crucial, since BL Lac objects are variable at all wavebands. I have analysed the MWL observations and conducted detailed variability and spectral studies in each wavelength range. The different kind of absorption at each wavelength as well as the influence of the host galaxy of the AGN has been considered to obtain the intrinsic jet spectrum. I have then applied the commonly used theoretical jet model, the SSC model, to the SED. I conducted a MWL campaign on a BL Lac object with the softest TeV spectrum, PKS 2005-489, during which it was observed in a very bright X-ray state. The good spectral coverage of the emission peaks allowed a detailed study of the SSC model. The extreme BL Lac object 1ES 0229+200 exhibits a hard intrinsic TeV spectrum. With my MWL campaign I found a clear cut-off in the optical range and therefore a high minimum Lorentz factor is needed to

  1. Multi-wavelength studies of TeV γ-ray emitting BL Lac objects

    Energy Technology Data Exchange (ETDEWEB)

    Kaufmann, Sarah Sabine

    2012-12-21

    The discovery of TeV γ-ray emission of BL Lac objects gave new insights in the particle acceleration and the emission processes of the highly relativistic jets. To shed light on the conditions in the high energetic jets of the TeV γ-ray emitting BL Lac objects, I have studied in great detail the spectral energy distribution (SED) of sources with different characteristics. BL Lac objects with exceptional very high energy spectra (soft and hard spectra) and with large differences in the emission peak frequencies, to cover the different classes of BL Lac objects, have been chosen. The basic aim of this thesis was, to study with new, simultaneous multi- avelength (MWL) observations, if the emission processes of these extreme cases of TeV BL Lac objects can be explained by the synchrotron Self-Compton (SSC) model which is well established for the class of BL Lac objects at lower energies. We proposed MWL observations in the optical, UV and X-ray regime, to be conducted simultaneous to very high energy observations with the H.E.S.S. experiment, to study the emission processes. Simultaneous observations are crucial, since BL Lac objects are variable at all wavebands. I have analysed the MWL observations and conducted detailed variability and spectral studies in each wavelength range. The different kind of absorption at each wavelength as well as the influence of the host galaxy of the AGN has been considered to obtain the intrinsic jet spectrum. I have then applied the commonly used theoretical jet model, the SSC model, to the SED. I conducted a MWL campaign on a BL Lac object with the softest TeV spectrum, PKS 2005-489, during which it was observed in a very bright X-ray state. The good spectral coverage of the emission peaks allowed a detailed study of the SSC model. The extreme BL Lac object 1ES 0229+200 exhibits a hard intrinsic TeV spectrum. With my MWL campaign I found a clear cut-off in the optical range and therefore a high minimum Lorentz factor is needed to

  2. Complex genomic rearrangement in CCS-LacZ transgenic mice.

    Science.gov (United States)

    Stroud, Dina Myers; Darrow, Bruce J; Kim, Sang Do; Zhang, Jie; Jongbloed, Monique R M; Rentschler, Stacey; Moskowitz, Ivan P G; Seidman, Jonathan; Fishman, Glenn I

    2007-02-01

    The cardiac conduction system (CCS)-lacZ insertional mouse mutant strain genetically labels the developing and mature CCS. This pattern of expression is presumed to reflect the site of transgene integration rather than regulatory elements within the transgene proper. We sought to characterize the genomic structure of the integration locus and identify nearby gene(s) that might potentially confer the observed CCS-specific transcription. We found rearrangement of chromosome 7 between regions D1 and E1 with altered transcription of multiple genes in the D1 region. Several lines of evidence suggested that regulatory elements from at least one gene, Slco3A1, influenced CCS-restricted reporter gene expression. In embryonic hearts, Slco3A1 was expressed in a spatial pattern similar to the CCS-lacZ transgene and was similarly neuregulin-responsive. At later stages, however, expression patterns of the transgene and Slco3A1 diverged, suggesting that the Slco3A1 locus may be necessary, but not sufficient to confer CCS-specific transgene expression in the CCS-lacZ line. (c) 2007 Wiley-Liss, Inc.

  3. Le lac Titicaca: histoire perdue d'une mer intérieure

    Directory of Open Access Journals (Sweden)

    1992-01-01

    Full Text Available Cet article tente de reconstruire l’histoire de la région du lac Titicaca et de son peuplement pour la période précédant l’arrivée des espagnols. Á cet effet, nous avons utilisé une approche multidisciplinaire (sédimentologie, archéologie, mythologie qui autorise, depuis l’amont et dans la longue durée, un nouvel éclairage des données historiques du XVIe siècle. Malgré les changements climatiques et politiques ayant affecté les rives du Titicaca avant la Conquête espagnole, il existe une continuité historique qui va de la civilisation de Pukará à Hatuncolla en passant par Tiwanaku. Si la documentation espagnole ne rend pas compte de l’importance des anciennes populations riveraines et notamment des pukinas, c’est qu’il était de l’intérêt des envahisseurs successifs (aymaras, incas, espagnols de l’occulter. EL LAGO TITICACA: HISTORIA PERDIDA DE UN MAR INTERIOR. Este artículo constituye un intento de reconstrucción de la historia del lago Titicaca y de su poblamiento por el período que precede la llegada de los españoles. En esta perspectiva, hemos utilizado una aproximación multidisciplinaria (sedimentología, arqueología, mitología que autoriza una nueva lectura de las fuentes históricas del siglo XVI, a partir de datos remotos y en la larga duración. A pesar de los cambios climáticos y políticos que afectaron las orillas del Titicaca antes de la Conquista española, existe una continuidad histórica que va de la cultura de Pukará hasta Hatuncolla (pasando por Tiwanaku. Si la documentación española no toma en cuenta la importancia de las antiguas poblaciones lacustres, particularmente los pukinas, es porque el interés de sus sucesivos vencedores (aymara, incas, españoles era de ocultarla. THE TITICACA LAKE: HISTORY LOST IN THE CENTER OF A DEEP IMMENSITY. This article comprises an attempt to reconstruct the Titicaca Lake history and its colonization during the period preceding the Spanish arrival. On

  4. Laccase 1 gene from Plutella xylostella (PxLac1) and its functions in humoral immune response.

    Science.gov (United States)

    Wang, Ze-Hua; Hu, Rong-Min; Ye, Xi-Qian; Huang, Jian-Hua; Chen, Xue-Xin; Shi, Min

    Laccase (EC 1.10.3.2) is a phenoloxidase found in many insect species. The Laccase 1 gene from Plutella xylostella (PxLac1) was cloned, and its expression patterns and functions were determined using qPCR and RNAi methods. The results showed that the expression levels of PxLac1 were consistently high in all larval stages, and the most abundant was in the midgut during the 4th instar stage. Moreover, the expression of PxLac1 was up-regulated in response to bacterial infection, and decreased 24 h after being parasitized by Cotesia vestalis. Further analyses indicated that the effect of parasitization on PxLac1 was induced by active C. vestalis Bracovirus (CvBV). Haemocyte-free hemolymph phenoloxidase (PO) activity was suppressed when PxLac1 was treated with RNAi. Our results provide evidence for a connection between the Laccase 1 gene and insect immunity, and revealed that parasitoid polydnavirus suppresses host PO activity via PxLac1 regulation. Copyright © 2018. Published by Elsevier Ltd.

  5. Accès aux soins des personnes originaires d&8217;Afrique subsaharienne vivant avec une hépatite B chronique

    OpenAIRE

    Vignier, N.; Spira, R. D.; Lert, F.; Pannetier, J.; Ravalihasy, Andrainolo; Gosselin, A.; Lydie, N.; Bouchaud, O.; Desgrées du Loû, Annabel; Grp, Anrs-Parcours

    2017-01-01

    Objectif : L'objectif de cette étude est d'analyser l'accès aux soins des personnes originaires d'Afrique subsaharienne (ASS) vivant avec une hépatite B chronique (HBC) en France. Méthodes : L'enquête ANRS-Parcours est une étude biographique réalisée en 2012-2013 auprès de personnes originaires d'ASS recrutées dans des services de prise en charge de l'HBC en Ile-de-France. Les données ont été recueillies en face-à-face à l'aide d'une grille biographique et d'un questionnaire standardisé. ...

  6. Dynamic model of gene regulation for the lac operon

    International Nuclear Information System (INIS)

    Angelova, Maia; Ben-Halim, Asma

    2011-01-01

    Gene regulatory network is a collection of DNA which interact with each other and with other matter in the cell. The lac operon is an example of a relatively simple genetic network and is one of the best-studied structures in the Escherichia coli bacteria. In this work we consider a deterministic model of the lac operon with a noise term, representing the stochastic nature of the regulation. The model is written in terms of a system of simultaneous first order differential equations with delays. We investigate an analytical and numerical solution and analyse the range of values for the parameters corresponding to a stable solution.

  7. Dynamic model of gene regulation for the lac operon

    Energy Technology Data Exchange (ETDEWEB)

    Angelova, Maia; Ben-Halim, Asma, E-mail: maia.angelova@northumbria.ac.uk, E-mail: asma.benhalim@northumbria.ac.uk [Intelligent Modelling Lab, School of Computing, Engineering and Information Sciences, Northumbria University, Newcastle upon Tyne NE2 1XE (United Kingdom)

    2011-03-01

    Gene regulatory network is a collection of DNA which interact with each other and with other matter in the cell. The lac operon is an example of a relatively simple genetic network and is one of the best-studied structures in the Escherichia coli bacteria. In this work we consider a deterministic model of the lac operon with a noise term, representing the stochastic nature of the regulation. The model is written in terms of a system of simultaneous first order differential equations with delays. We investigate an analytical and numerical solution and analyse the range of values for the parameters corresponding to a stable solution.

  8. Enzymatic Synthesis of N-Acetyllactosamine (LacNAc Type 1 Oligomers and Characterization as Multivalent Galectin Ligands

    Directory of Open Access Journals (Sweden)

    Thomas Fischöder

    2017-08-01

    Full Text Available Repeats of the disaccharide unit N-acetyllactosamine (LacNAc occur as type 1 (Galβ1, 3GlcNAc and type 2 (Galβ1, 4GlcNAc glycosylation motifs on glycoproteins and glycolipids. The LacNAc motif acts as binding ligand for lectins and is involved in many biological recognition events. To the best of our knowledge, we present, for the first time, the synthesis of LacNAc type 1 oligomers using recombinant β1,3-galactosyltransferase from Escherichia coli and β1,3-N-acetylglucosaminyltranferase from Helicobacter pylori. Tetrasaccharide glycans presenting LacNAc type 1 repeats or LacNAc type 1 at the reducing or non-reducing end, respectively, were conjugated to bovine serum albumin as a protein scaffold by squarate linker chemistry. The resulting multivalent LacNAc type 1 presenting neo-glycoproteins were further studied for specific binding of the tumor-associated human galectin 3 (Gal-3 and its truncated counterpart Gal-3∆ in an enzyme-linked lectin assay (ELLA. We observed a significantly increased affinity of Gal-3∆ towards the multivalent neo-glycoprotein presenting LacNAc type 1 repeating units. This is the first evidence for differences in glycan selectivity of Gal-3∆ and Gal-3 and may be further utilized for tracing Gal-3∆ during tumor progression and therapy.

  9. VizieR Online Data Catalog: The CLASS BL Lac sample (Marcha+, 2013)

    Science.gov (United States)

    Marcha, M. J. M.; Caccianiga, A.

    2014-04-01

    This paper presents a new sample of BL Lac objects selected from a deep (30mJy) radio survey of flat spectrum radio sources (the CLASS blazar survey). The sample is one of the largest well-defined samples in the low-power regime with a total of 130 sources of which 55 satisfy the 'classical' optical BL Lac selection criteria, and the rest have indistinguishable radio properties. The primary goal of this study is to establish the radio luminosity function (RLF) on firm statistical ground at low radio luminosities where previous samples have not been able to investigate. The gain of taking a peek at lower powers is the possibility to search for the flattening of the luminosity function which is a feature predicted by the beaming model but which has remained elusive to observational confirmation. In this study, we extend for the first time the BL Lac RLF down to very low radio powers ~1022W/Hz, i.e. two orders of magnitude below the RLF currently available in the literature. In the process, we confirm the importance of adopting a broader, and more physically meaningful set of classification criteria to avoid the systematic missing of low-luminosity BL Lacs. Thanks to the good statistics we confirm the existence of weak but significant positive cosmological evolution for the BL Lac population, and we detect, for the first time the flattening of the RLF at L~1025W/Hz in agreement with the predictions of the beaming model. (1 data file).

  10. β2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes

    DEFF Research Database (Denmark)

    Thomsen, Mette; Dahl, Morten; Tybjærg-Hansen, Anne

    2012-01-01

    The β(2)-adrenergic receptor (ADRB2) influences regulation of energy balance by stimulating catecholamine-induced lipolysis in adipose tissue. The rare functional ADRB2rs1800888(Thr164Ile) polymorphism could therefore influence risk of obesity and subsequently diabetes.......The β(2)-adrenergic receptor (ADRB2) influences regulation of energy balance by stimulating catecholamine-induced lipolysis in adipose tissue. The rare functional ADRB2rs1800888(Thr164Ile) polymorphism could therefore influence risk of obesity and subsequently diabetes....

  11. 2731-IJBCS-Article-Pivot Amour Sachi

    African Journals Online (AJOL)

    hp

    vers le lac par les eaux de ruissellement. 29,64% des personnes enquêtées convoyaient des produits pétroliers à travers le lac et avaient souligné que ces produits pouvaient se déverser dans le lac lors du transport. Formation sur les règles d'hygiène. Parmi les personnes enquêtées, seuls. 43,21% avaient reçu une ...

  12. PRODUCTION HALIEUTIQUE DU LAC FAE (BASSIN DU SAN ...

    African Journals Online (AJOL)

    about 5.229 millions CFA for the shrimp production at the rate of 1500 Flkg. .... Figure 1 Lac Fae-Localisation geographique, zones de production, secteurs et ... embankment dam ; d : water intake for regulating the threshold level of water in the.

  13. Evolution and Biophysics of the Escherichia coli lac Operon

    Science.gov (United States)

    Ray, J. Christian; Igoshin, Oleg; Quan, Selwyn; Monds, Russell; Cooper, Tim; Balázsi, Gábor

    2011-03-01

    To understand, predict, and control the evolution of living organisms, we consider biophysical effects and molecular network architectures. The lactose utilization system of E. coli is among the most well-studied molecular networks in biology, making it an ideal candidate for such studies. Simulations show how the genetic architecture of the wild-type operon attenuates large metabolic intermediate fluctuations that are predicted to occur in an equivalent system with the component genes on separate operons. Quantification of gene expression in the lac operon evolved in growth conditions containing constant lactose, alternating with glucose, or constant glucose, shows characteristic gene expression patterns depending on conditions. We are simulating these conditions to show context-dependent biophysical sources and costs of different lac operon architectures.

  14. Water quality and hydrology of the Lac Vieux Desert watershed, Gogebic County, Michigan, and Vilas County, Wisconsin, 2002-04

    Science.gov (United States)

    Weaver, T.L.; Neff, B.P.; Ellis, J.M.

    2005-01-01

    Lac Vieux Desert is a prominent 6.6 square-mile lake that straddles the Michigan-Wisconsin border and forms the headwaters of the Wisconsin River. For generations, the Lac Vieux Desert Band of Lake Superior Chippewa Indians have used Lac Vieux Desert and the surrounding area for growing and harvesting wild rice, and hunting and fishing. The Lac Vieux Desert Band is concerned about the impact of lake-stage regulation on hydrology and ecology, and the impact on water quality of development along and near the shore, and recreational watercraft use and sport fishing. In 2005, the U.S. Geological Survey completed a water-resources investigation of the Lac Vieux Desert watershed in cooperation with the Lac Vieux Desert Band of Lake Superior Chippewa Indians.Water quality of Lac Vieux Desert is typical of many lakes in the northern United States. Trophic State Index calculations classify Lac Vieux Desert as a highly productive eutrophic lake. The pH of water in Lac Vieux Desert ranged from 6.5 to 9.5, and specific conductance ranged from 62 to 114 µs/cm. Chloride concentration was less than 1.5 mg/L, indicating little effect from septic-tank or road-salt input. Results indicate that the water can be classified as soft, with hardness concentrations reported as calcium carbonate ranging from 29 to 49 mg/L. Concentrations of calcium, magnesium, chloride, and other dissolved solids ranged from 47 to 77 mg/L. Alkalinity of Lac Vieux Desert ranged from 27 to 38 mg/L.Pervasive aquatic blooms, including a bloom noted during the September 2003 sampling, are apparently common in late summer. Biological productivity at Lac Vieux Desert does not appear to have changed appreciably between 1973 and 2004. In the current study, total phosphorus concentrations ranged from 0.01 to 0.064 mg/L and dissolved nitrite plus nitrate nitrogen concentrations ranged from at, or below detection limit to 0.052 mg/L. Overabundance of nutrients in Lac Vieux Desert, particularly nitrogen and phosphorus

  15. Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia

    International Nuclear Information System (INIS)

    Knoll, Susanne; Zimmer, Sabiene; Hinney, Anke; Scherag, André; Neubauer, Andreas; Hebebrand, Johannes

    2008-01-01

    At present pathogenic mechanisms of cancer cachexia are poorly understood. Previous evidence in animal models implicates the melanocortin-4 receptor gene (MC4R) in the development of cancer cachexia. In humans, MC4R mutations that lead to an impaired receptor function are associated with obesity; in contrast, the most frequent polymorphism (Val103Ile, rs2229616; heterozygote frequency approximately 2%) was shown to be negatively associated with obesity. We tested if cancer patients that are homo-/heterozygous for the Val103Ile polymorphism are more likely to develop cachexia and/or a loss of appetite than non-carriers of the 103Ile-allele. BMI (body mass index in kg/m 2 ) of 509 patients (295 males) with malignant neoplasms was determined; additionally patients were asked about premorbid/pretherapeutical changes of appetite and weight loss. Cachexia was defined as a weight loss of at least 5% prior to initiation of therapy; to fulfil this criterion this weight loss had to occur independently of other plausible reasons; in single cases weight loss was the initial reason for seeing a physician. The average age in years (± SD) was 59.0 ± 14.5 (males: 58.8 ± 14.0, females 59.2 ± 14.0). Blood samples were taken for genotyping of the Val103Ile by PCR- RFLP. Most of the patients suffered from lymphoma, leukaemia and gastrointestinal tumours. 107 of the patients (21%) fulfilled our criteria for cancer cachexia. We did not detect association between the Val103Ile polymorphism and cancer cachexia. However, if we exploratively excluded the patients with early leucaemic stages, we detected a trend towards the opposite effect (p < 0.05); heterozygotes for the 103Ile-allele developed cancer cachexia less frequently in comparison to the rest of the study group. Changes of appetite were not associated with the 103Ile-allele carrier status (p > 0.39). Heterozygotes for the 103Ile-allele are not more prone to develop cancer cachexia than patients without this allele; possibly

  16. Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia

    Energy Technology Data Exchange (ETDEWEB)

    Knoll, Susanne; Zimmer, Sabiene [Department of Child and Adolescent Psychiatry, University of Duisburg-Essen (Germany); Department of Hematology/Oncology/Immunology, University of Marburg (Germany); Hinney, Anke [Department of Child and Adolescent Psychiatry, University of Duisburg-Essen (Germany); Scherag, André [Zentrum for clinical studies food (ZKSE) c/o Institute for Medical Informatics, Biometry and Epidemiology, University Duisburg-Essen, Essen (Germany); Neubauer, Andreas [Department of Hematology/Oncology/Immunology, University of Marburg (Germany); Hebebrand, Johannes [Department of Child and Adolescent Psychiatry, University of Duisburg-Essen (Germany)

    2008-03-31

    At present pathogenic mechanisms of cancer cachexia are poorly understood. Previous evidence in animal models implicates the melanocortin-4 receptor gene (MC4R) in the development of cancer cachexia. In humans, MC4R mutations that lead to an impaired receptor function are associated with obesity; in contrast, the most frequent polymorphism (Val103Ile, rs2229616; heterozygote frequency approximately 2%) was shown to be negatively associated with obesity. We tested if cancer patients that are homo-/heterozygous for the Val103Ile polymorphism are more likely to develop cachexia and/or a loss of appetite than non-carriers of the 103Ile-allele. BMI (body mass index in kg/m{sup 2}) of 509 patients (295 males) with malignant neoplasms was determined; additionally patients were asked about premorbid/pretherapeutical changes of appetite and weight loss. Cachexia was defined as a weight loss of at least 5% prior to initiation of therapy; to fulfil this criterion this weight loss had to occur independently of other plausible reasons; in single cases weight loss was the initial reason for seeing a physician. The average age in years (± SD) was 59.0 ± 14.5 (males: 58.8 ± 14.0, females 59.2 ± 14.0). Blood samples were taken for genotyping of the Val103Ile by PCR- RFLP. Most of the patients suffered from lymphoma, leukaemia and gastrointestinal tumours. 107 of the patients (21%) fulfilled our criteria for cancer cachexia. We did not detect association between the Val103Ile polymorphism and cancer cachexia. However, if we exploratively excluded the patients with early leucaemic stages, we detected a trend towards the opposite effect (p < 0.05); heterozygotes for the 103Ile-allele developed cancer cachexia less frequently in comparison to the rest of the study group. Changes of appetite were not associated with the 103Ile-allele carrier status (p > 0.39). Heterozygotes for the 103Ile-allele are not more prone to develop cancer cachexia than patients without this allele

  17. Spectroscopy of optically selected BL Lac objects and their γ-ray emission

    Energy Technology Data Exchange (ETDEWEB)

    Sandrinelli, A.; Treves, A.; Farina, E. P.; Landoni, M. [Università degli Studi dell' Insubria, Via Valleggio 11, I-22100 Como (Italy); Falomo, R. [INAF-Osservatorio Astronomico di Padova, Vicolo dell Osservatorio 5, I-35122 Padova (Italy); Foschini, L.; Sbarufatti, B., E-mail: angela.sandrinelli@brera.inaf.it [INAF-Osservatorio Astronomico di Brera, Via Emilio Bianchi 46, I-23807 Merate (Italy)

    2013-12-01

    We present Very Large Telescope optical spectroscopy of nine BL Lac objects of unknown redshift belonging to the list of optically selected radio-loud BL Lac candidates. We explore their spectroscopic properties and possible link with gamma-ray emission. From the new observations we determine the redshifts of four objects from faint emission lines or from absorption features of their host galaxies. In three cases we find narrow intervening absorptions from which a lower limit to the redshift is inferred. For the remaining two featureless sources, lower limits to the redshift are deduced from the absence of spectral lines. A search for γ counterpart emission shows that six out of the nine candidates are Fermi γ-ray emitters and we find two new detections. Our analysis suggests that most of the BL Lac objects still lacking redshift information are most likely located at high redshifts.

  18. THE CONTRIBUTION OF FERMI -2LAC BLAZARS TO DIFFUSE TEV–PEV NEUTRINO FLUX

    Energy Technology Data Exchange (ETDEWEB)

    Aartsen, M. G. [Department of Physics, University of Adelaide, Adelaide, 5005 (Australia); Abraham, K. [Physik-department, Technische Universität München, D-85748 Garching (Germany); Ackermann, M. [DESY, D-15735 Zeuthen (Germany); Adams, J. [Dept. of Physics and Astronomy, University of Canterbury, Private Bag 4800, Christchurch (New Zealand); Aguilar, J. A.; Ansseau, I. [Université Libre de Bruxelles, Science Faculty CP230, B-1050 Brussels (Belgium); Ahlers, M. [Dept. of Physics and Wisconsin IceCube Particle Astrophysics Center, University of Wisconsin, Madison, WI 53706 (United States); Ahrens, M. [Oskar Klein Centre and Dept. of Physics, Stockholm University, SE-10691 Stockholm (Sweden); Altmann, D.; Anton, G. [Erlangen Centre for Astroparticle Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91058 Erlangen (Germany); Andeen, K. [Department of Physics, Marquette University, Milwaukee, WI, 53201 (United States); Anderson, T.; Arlen, T. C. [Dept. of Physics, Pennsylvania State University, University Park, PA 16802 (United States); Archinger, M.; Baum, V. [Institute of Physics, University of Mainz, Staudinger Weg 7, D-55099 Mainz (Germany); Arguelles, C.; Axani, S. [Dept. of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Auffenberg, J. [III. Physikalisches Institut, RWTH Aachen University, D-52056 Aachen (Germany); Bai, X. [Physics Department, South Dakota School of Mines and Technology, Rapid City, SD 57701 (United States); Barwick, S. W., E-mail: thorsten.gluesenkamp@fau.de [Dept. of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Collaboration: IceCube Collaboration; and others

    2017-01-20

    The recent discovery of a diffuse cosmic neutrino flux extending up to PeV energies raises the question of which astrophysical sources generate this signal. Blazars are one class of extragalactic sources which may produce such high-energy neutrinos. We present a likelihood analysis searching for cumulative neutrino emission from blazars in the 2nd Fermi -LAT AGN catalog (2LAC) using IceCube neutrino data set 2009-12, which was optimized for the detection of individual sources. In contrast to those in previous searches with IceCube, the populations investigated contain up to hundreds of sources, the largest one being the entire blazar sample in the 2LAC catalog. No significant excess is observed, and upper limits for the cumulative flux from these populations are obtained. These constrain the maximum contribution of 2LAC blazars to the observed astrophysical neutrino flux to 27% or less between around 10 TeV and 2 PeV, assuming the equipartition of flavors on Earth and a single power-law spectrum with a spectral index of −2.5. We can still exclude the fact that 2LAC blazars (and their subpopulations) emit more than 50% of the observed neutrinos up to a spectral index as hard as −2.2 in the same energy range. Our result takes into account the fact that the neutrino source count distribution is unknown, and it does not assume strict proportionality of the neutrino flux to the measured 2LAC γ -ray signal for each source. Additionally, we constrain recent models for neutrino emission by blazars.

  19. METHODICAL APPROACHES TO THE CREATION MOOC (EXPERIENCE LAC

    Directory of Open Access Journals (Sweden)

    Larysa Nozdrina

    2016-03-01

    Full Text Available The article presents a number of problems, determining the current state of development of the domestic market of massive open online courses (MOOC. Considering the aim of the research, there is described national experience in this area, proposed and substantiated a number of the criteria and methodological approaches to the implementation of MOOC in higher education. The development of MOOC in the Lviv Academy of Commerce (LAC is reviewed as example. The main factors which determine the success of this educational innovation in the domestic market and are put under the research are software platforms, multimedia software for creating video lectures, course structure and support the learning process. The results of study which have been analyzed in this course can have a positive impact on the functioning of the market MOOC in Ukrainian universities. The article focuses on finding the ways of improving the process of developing and implementing MOOC in higher education in the example of LAC where Web-center on the MOODLE platform is used for e-learning. Further research should focus on the development of institutional mechanisms to ensure the effective design, implementation and operation of the MOOC in the universities in Ukraine. Particular attention during learning in massive open online course should be aimed at improving the educational process and to strengthen student's motivation in MOOC. Experience of MOOC's development in LAC can be useful at creating similar courses at other institutions of higher education in the different platforms, both MOODLE, and on the others

  20. Süt Proteinlerinin RP-HPLC ile Saptanması (İngilizce

    Directory of Open Access Journals (Sweden)

    Zerrin Yüksel

    2015-02-01

    Full Text Available Bu çalışmada, κ-, α- and β-kazein ile α-laktalbumin and β-laktoglobulin, bir RP kolonunun kullanıldığı HPLC-UV ile basit ve hızlı bir yöntem geliştirilerek saptanmıştır. Gradient elüsyonu, 1 ml/dk akış hızında ve 25 oC sıcaklıkta iki çözücü karışımı kullanılarak yürütülmüştür. A çözücüsü asetonitril: su:trifloroasetik asit (100:900:1 ve B çözücüsü asetonitril: su: trifloroasetik asit (100:900:1 karışımlarından oluşmaktadır. Akış, bir UV dedektörü kullanılarak 220 nm’de kaydedilmiştir. Farklı yöntemler kullanılarak RP-HPLC analizi için hazırlanan örneklerde, süt proteinlerine ait farklı kromatografik profiller elde edilmiştir. Diğer örnek hazırlama yöntemlerine kıyasla, enjeksiyondan önce belirtilen oranlarda A ve B çözücülerinin kullanıldığı örnek hazırlama yöntemi ile separasyonun daha keskin ve efektif olduğu ortaya konulmuştur. Bu çalışmada ortaya konulan örnek hazırlama tekniği ve elusyon pratiği ile, süt proteinlerinin analizi basit, hızlı ve duyarlı bir şekilde gerçekleştirilmiştir.

  1. Carcaça de borregos Ile de France inteiros ou castrados e Hampshire down castrados abatidos aos doze meses de idade Carcass of intact or castrated Ile de France and castrated Hampshire down lambs slaughtered at twelve months of age

    Directory of Open Access Journals (Sweden)

    Edson Luis de Azambuja Ribeiro

    2001-06-01

    Full Text Available Um total de 24 borregos, sendo oito Ile de France inteiros, oito Ile de France castrados e oito Hampshire Down castrados, foram utilizados com o objetivo de avaliar características qualitativas e quantitativas da carcaça. Os animais foram mantidos exclusivamente em pastagem de grama Coast-Cross, sendo abatidos aos 12 meses de idade. As carcaças provenientes de animais inteiros da raça Ile de France apresentaram significativamente maior percentagem de pescoço do que as de animais castrados da mesma raça, sendo essa a única diferença encontrada entre esses dois grupos. Porém, foram observadas diferenças na composição tecidual da paleta entre as raças, sendo que os animais da raça Ile de France (inteiros ou castrados apresentaram maior percentual de músculo e maior relação músculo/osso do que os animais da raça Hampshire Down. Os resultados indicam que, por não haver diferenças importantes entre carcaças e carnes de animais inteiros e castrados abatidos aos 12 meses de idade, o uso da castração pode ser dispensado em sistemas intensivos de produção de carne ovinaA total of 24 lambs, eight intact Ile de France, eight castrated Ile de France and eight castrated Hampshire Down, were used in this experiment with the main objective of evaluating quantitative and qualitative carcass traits. The animals were raised on a Coast-Cross pasture and slaughtered at 12 months of age. Carcasses from intact Ile de France lambs had significantly more neck than carcasses from castrated Ile de France lambs. No other differences were observed between carcasses from intact or castrated Ile de France. However, differences between breeds were observed for tissue composition of the shoulder. Shoulders from Ile de France carcasses (intact or castrated presented greater percentage of muscles and greater relation of muscles/bones than shoulders from Hampshire Down lambs. Results indicate that intact males can be recommended for sheep meat production

  2. A geological survey of the Lac du Bonnet batholith, Manitoba

    International Nuclear Information System (INIS)

    McCrank, G.F.D.

    1985-02-01

    This report presents the results of a geological survey of the Lac du Bonnet batholith in Manitoba. The survey consisted of field mapping of the lithologies and the joint systems throughout the batholith, and the examination of lineaments identified on aerial photographs and Landsat imagery. Petrographic descriptions and a map of the lithologies, an analysis of the fracture systems and a lineament map are presented. The results of various regional geophysical surveys were used as an aid to the interpretation of the batholith's contacts and in the interpretation of lineaments as possible faults. A comparison of the Lac du Bonnet Batholith with the Eye-Dashwa Lakes Pluton near Atikokan, Ontario is also presented

  3. Langmuir-Blodgett (LB) yöntemi ile elde edilen çeşitli CdS ve Pb ince filmlerinin fiziksel özelliklerinin elektrik kuvvet mikroskobu (EKM) ile incelenmesi

    OpenAIRE

    ARSLAN, Melike

    2011-01-01

    Bu tez çalışmasında, Langmuir-Blodgett (LB) yöntemi ile elde edilen farklı pH derecelerine sahip Kadmiyum Sülfür (CdS) ve Kurşun (Pb) ince filminin topografik ve elektriksel özellikleri incelenmiştir. LB ince filmlerinin topografik özellikleri ve elektriksel özellikleri NT-MDT marka Taramalı Uç Mikroskobu (TUM) ile incelenmiştir. Yüzey morfolojik özel...

  4. Les carbonates néogènes de Sainte Croix (Iles Vierges. Etude stratigraphique et pétrophysique Neogene Carbonates At Saint Croix, Virgin Islands. Stratigraphic and Petrophysical Study

    Directory of Open Access Journals (Sweden)

    Andreieff P.

    2006-11-01

    Full Text Available Un échantillonnage systématique des principaux affleurements des séries carbonatées néogènes de Sainte Croix (Iles Vierges a permis de préciser leur extension stratigraphique. C'est ainsi que la section-type de la formation Kingshill, qui avait été récemment attribuée au Miocène supérieur, est désormais datée du Miocène moyen d'après son riche contenu faunistique en foraminifères planctoniques et nannofossiles calcaires. Les diverses mesures pétrophysiques effectuées dans des niveaux d'environnement de dépôts différents (plate-forme, pente, bassin tendent à prouver que de bonnes porosités et perméabilités, donc de bons réservoirs, pourraient être trouvées dans des séries de pentes ou de fond de bassins associés à des plates-formes carbonatées. Systematic sampling of the main outcrops of Neogene carbonate series on Saint Croix, Virgin Islands, has enabled their stratigraphic extension to be determined. In this way, the Kingshill formation type section, which has recently been attributed to the late Miocene, is henceforth dated from the middle Miocene according to planktonic foraminifers and calcareous nannofossils. The different petrophysical measurements made in strata originated from different depositional environments (shelf, slope, basin tend to prove that good porosities and permeabilities, hence good reservoirs, might be found in slope or basin-bottom series associated with carbonate banks.

  5. CLUSTERING OF γ-RAY-SELECTED 2LAC FERMI BLAZARS

    Energy Technology Data Exchange (ETDEWEB)

    Allevato, V.; Finoguenov, A. [Department of Physics, University of Helsinki, Gustaf Hällströmin katu 2a, FI-00014 Helsinki (Finland); Cappelluti, N. [University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250 (United States)

    2014-12-20

    We present the first measurement of the projected correlation function of 485 γ-ray-selected blazars, divided into 175 BL Lacertae (BL Lacs) and 310 flat-spectrum radio quasars (FSRQs) detected in the 2 year all-sky survey by the Fermi-Large Area Telescope. We find that Fermi BL Lacs and FSRQs reside in massive dark matter halos (DMHs) with log M{sub h} = 13.35{sub −0.14}{sup +0.20} and log M{sub h} = 13.40{sub −0.19}{sup +0.15} h {sup –1} M {sub ☉}, respectively, at low (z ∼ 0.4) and high (z ∼ 1.2) redshift. In terms of clustering properties, these results suggest that BL Lacs and FSRQs are similar objects residing in the same dense environment typical of galaxy groups, despite their different spectral energy distributions, power, and accretion rates. We find no difference in the typical bias and hosting halo mass between Fermi blazars and radio-loud active galactic nuclei (AGNs), supporting the unification scheme simply equating radio-loud objects with misaligned blazar counterparts. This similarity in terms of the typical environment they preferentially live in, suggests that blazars tend to occupy the center of DMHs, as already pointed out for radio-loud AGNs. This implies, in light of several projects looking for the γ-ray emission from DM annihilation in galaxy clusters, a strong contamination from blazars to the expected signal from DM annihilation.

  6. le lac municipal d'Ebol

    African Journals Online (AJOL)

    Nsom Zamo, Annie Claude

    de la prolifération anarchique des algues qui consomment tout l'oxygène nécessaire à la vie ... derrière l'Hôpital Régional d'Ebolowa, il reçoit les eaux des rivières Mfoumou et Bengo'o [6]. ..... approvisionnement continu en éléments nutritifs.

  7. Chapitre 9. L'industrie pétrolière au Venezuela : rupture, conflits et gestion des espaces côtiers1

    OpenAIRE

    Ramousse, Didier

    2015-01-01

    RésuméLongtemps dévolu à des activités agro-exportatrices, le littoral vénézuélien a été complètement transformé par la croissance rapide et souvent mal contrôlée de l'industrie pétrolière, à partir des années 1930. La façade caraïbe, plus particulièrement autour du lac de Maracaibo, est devenue la région la plus dynamique et la plus prospère du pays, tandis que les populations rurales venaient s'entasser dans les villes côtières. Pourtant, le développement économique du littoral pose de nomb...

  8. Louisiana SIP: LAC 33:III Ch 21 Subchap J, 2147--Limiting Volatile Organic Compound (VOC) Emissions from Reactor Processes and Distillation Operations in Synthetic Organic Chemical manufacturing Industry (SOCMI); SIP effective 1998-02-02 (LAc74) to more..

    Science.gov (United States)

    Louisiana SIP: LAC 33:III Ch 21 Subchap J, 2147--Limiting Volatile Organic Compound (VOC) Emissions from Reactor Processes and Distillation Operations in Synthetic Organic Chemical manufacturing Industry (SOCMI); SIP effective 1998-02-02 (LAc74) more...

  9. The BL Lac objects PKS 1144-379

    International Nuclear Information System (INIS)

    Nicolson, G.D.; Glass, I.S.; Feast, M.W.; Andrews, P.J.

    1979-01-01

    The highly variable radio source PKS 1144-379 has been monitored at 13 cm and 6 cm over a period of 3 years. It has been identified with an object whose photographic image is star-like. From infrared photometry, UBVRsub(KC)Isub(KC) photometry and spectroscopy, it is concluded that PKS 1144-379 is a BL Lac object with msub(v) approximately = 16.2. (author)

  10. Gtl2lacZ, an insertional mutation on mouse chromosome 12 with parental origin-dependent phenotype.

    Science.gov (United States)

    Schuster-Gossler, K; Simon-Chazottes, D; Guenet, J L; Zachgo, J; Gossler, A

    1996-01-01

    We have produced a transgenic mouse line, Gtl2lacZ (Gene trap locus 2), that carries an insertional mutation with a dominant modified pattern of inheritance:heterozygous Gtl2lacZ mice that inherited the transgene from the father show a proportionate dwarfism phenotype, whereas the penetrance and expressivity of the phenotype is strongly reduced in Gtl2lacZ mice that inherited the transgene from the mother. On a mixed genetic background this pattern of inheritance was reversible upon transmission of the transgene through the germ line of the opposite sex. On a predominantly 129/Sv genetic background, however, transgene passage through the female germ line modified the transgene effect, such that the penetrance of the mutation was drastically reduced and the phenotype was no longer obvious after subsequent male germ line transmission. Expression of the transgene, however, was neither affected by genetic background nor by parental legacy. Gtl2lacZ maps to mouse Chromosome 12 in a region that displays imprinting effects associated with maternal and paternal disomy. Our results suggest that the transgene insertion in Gtl2lacZ mice affects an endogenous gene(s) required for fetal and postnatal growth and that this gene(s) is predominantly paternally expressed.

  11. Extruder ile Pişirme Yönteminin Gıda Bileşim Öğeleri

    Directory of Open Access Journals (Sweden)

    Nevzat Artık

    2015-02-01

    Full Text Available Gıdalara uygulanan diğer ısıl işlemler gibi extruder ile pişirme yönteminde yararlı ve zararlı etkileri birlikte söz konusudur. Bu yöntemin yararlı etkisi; gıdanın özelliklerini olumsuz etkileyen faktörlerin elemine edilmesi; olumsuz etkisi ise, proteinler ile şekerler arasında oluşan Maillard tepkimesidir. Anılan tepkime ile proteinlerin besleyici niteliği azalmaktadır. Ayrıca ısıl işlem nedeniyle vitamin kayıpları söz konusu olmaktadır (Bjorck ve Asp, 1982.

  12. Modeling of pollution aerosols in Ile-de-France

    International Nuclear Information System (INIS)

    Hodzic, A.

    2005-10-01

    The modeling of aerosols is a major stake in the understanding of the emission processes and evolution of particulates in the atmosphere. However, the parameterizations used in today's aerosol models still comprise many uncertainties. This work has been motivated by the need of better identifying the weaknesses of aerosols modeling tools and by the necessity of having new validation methods for a 3D evaluation of models. The studies have been carried out using the CHIMERE chemistry-transport model, which allows to simulate the concentrations and physico-chemical characteristics of pollution aerosols at the European scale and in Ile-de-France region. The validation approach used is based on the complementarity of the measurements performed on the ground by monitoring networks with those acquired during the ESQUIF campaign (study and simulation of air quality in Ile-de-France), with lidar and photometric measurements and with satellite observations. The comparison between the observations and the simulations has permitted to identify and reduce the modeling errors, and to characterize the aerosol properties in the vicinity of an urban area. (J.S.)

  13. CYP1A1 Ile462Val polymorphism contributes to lung cancer susceptibility among lung squamous carcinoma and smokers: a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Ya-Nan Ji

    Full Text Available Many studies have examined the association between the CYP1A1 Ile462Val gene polymorphisms and lung cancer risk in various populations, but their results have been inconsistent. To assess this relationship more precisely, a meta-analysis was performed. Ultimately, 43 case-control studies, comprising 19,228 subjects were included. A significantly elevated lung cancer risk was associated with 2 Ile462Val genotype variants (for Val/Val vs Ile/Ile: OR = 1.22, 95% CI = 1.08-1.40; for (Ile/Val +Val/Val vs Ile/Ile: OR = 1.15, 95% CI = 1.07-1.23 in overall population. In the stratified analysis, a significant association was found in Asians, Caucasians and lung SCC, not lung AC and lung SCLC. Additionally, a significant association was found in smoker population and not found in non-smoker populations. This meta-analysis suggests that the Ile462Val polymorphisms of CYP1A1 correlate with increased lung cancer susceptibility in Asian and Caucasian populations and there is an interaction with smoking status, but these associations vary in different histological types of lung caner.

  14. High-level expression of Bacillus naganoensis pullulanase from recombinant Escherichia coli with auto-induction: effect of lac operator.

    Directory of Open Access Journals (Sweden)

    Yao Nie

    Full Text Available Pullulanase plays an important role in specific hydrolysis of branch points in amylopectin and is generally employed as an important enzyme in starch-processing industry. So far, however, the production level of pullulanase is still somewhat low from wide-type strains and even heterologous expression systems. Here the gene encoding Bacillus naganoensis pullulanase was amplified and cloned. For expression of the protein, two recombinant systems, Escherichia coli BL21(DE3/pET-20b(+-pul and E. coli BL21(DE3/pET-22b(+-pul, were constructed, both bearing T7 promoter and signal peptide sequence, but different in the existance of lac operator and lacI gene encoding lac repressor. Recombinant pullulanase was initially expressed with the activity of up to 14 U/mL by E. coli BL21(DE3/pET-20b(+-pul with IPTG induction in LB medium, but its expression level reduced continually with the extension of cryopreservation time and basal expression was observed. However, E. coli BL21(DE3/pET-22b(+-pul , involving lac operator downstream of T7 promoter to regulate foreign gene transcription, exhibited pullulanase activity consistently without detected basal expression. By investigating the effect of lac operator, basal expression of foreign protein was found to cause expression instability and negative effect on production of target protein. Thus double-repression strategy was proposed that lac operators in both chromosome and plasmid were bound with lac repressor to repress T7 RNA polymerase synthesis and target protein expression before induction. Consequently, the total activity of pullulanase was remarkably increased to 580 U/mL with auto-induction by lac operator-involved E. coli BL21(DE3/pET-22b(+-pul. When adding 0.6% glycine in culture, the extracellular production of pullulanase was significantly improved with the extracellular activity of 502 U/mL, which is a relatively higher level achieved to date for extracellular production of pullulanase. The

  15. L'algue alimentaire Spirulina sp. Découverte de lacs naturels à Wadi el Natroun en République Arabe d'Egypte Spirulina Sp. Food Alga. Discovery of Natural Lakes At Wadi El Natrun in the Arab Republic of Egypt

    Directory of Open Access Journals (Sweden)

    Abdin El Sherif S. A.

    2006-11-01

    Full Text Available Bien que connue depuis les temps les plus anciens, la dépression de Wadi el Natroun n'avait jamais été prospectée autrement que pour sa richesse en sels minéraux. C'est en 1977 que les auteurs, cherchant à savoir s'il existait des lacs naturels à Spirulines en République Arabe d'Égypte, découvrirent dans la dépression de Wadi el Natroun certains lacs comme Abou Gobara et El Khadra où croissaient spontanément les algues spirulines. Le climat du site, l'origine et la composition des eaux, ainsi que la concentration en algues, ont été étudiés afin d'estimer la productivité du site en vue d'une éventuelle exploitation industrielle. L'exploitation de ces lacs permettrait de mettre en valeur le site de Wadi el Natroun par la production d'une substance très riche en protéine pour l'alimentation humaine dont à tant besoin la République Arabe d'Égypte. Even though it has been known from olden days, the depression of Wadi el Natrun had never been prospected other than for its wealth of mineral salts. It was in 1977 that the authors began searching for natural lakes with Spirulina algae in the Arab Republic of Egypt and, in the depression of Wadi el Natrun, discovered varions lakes such as Abu Gobara and El Khadra where Spirulina algae grew in a natural state. The climate of the site, the original and composition of the water as well as the algae concentration were analyzed to evaluate the productivity of the site for eventual industrial exploitation. The exploitation of these lakes would give value to the Wadi el Natrun site by producing a very protein-rich substance for human nourishment which the Arab Republic of Egypt needs so badly.

  16. Lac repressor: Crystallization of intact tetramer and its complexes with inducer and operator DNA

    International Nuclear Information System (INIS)

    Pace, H.C.; Lu, P.; Lewis, M.

    1990-01-01

    The intact lac repressor tetramer, which regulates expression of the lac operon in Escherichia coli, has been crystallized in the native form, with an inducer, and in a ternary complex with operator DNA and an anti-inducer. The crystals without DNA diffract to better than 3.5 angstrom. They belong to the monoclinic space group C2 and have cell dimensions a = 164.7 angstrom, b = 75.6 angstrom, and c = 161.2 angstrom, with α = γ = 90 degree and β = 125.5 degree. Cocrystals have been obtained with a number of different lac operator-related DNA fragments. The complex with a blunt-ended 16-base-pair strand yielded tetragonal bipyramids that diffract to 6.5 angstrom. These protein-DNA cocrystals crack upon exposure to the gratuitous inducer isopropyl β-D-thiogalactoside, suggesting a conformational change in the repressor-operator complex

  17. Preliminary Assessment of Heavy Metal Pollution of Opa Reservoir, Ile

    African Journals Online (AJOL)

    big timmy

    Awolowo University (OAU), Ile-Ife, Nigeria, with a view to assessing its pollution level. ... Heavy metals are not biodegradable, but are assimilated .... samples were filtered (with Whatman filter paper. No 42) and ..... acidity,Water, Air Soil Pollut.

  18. Characterization of pLAC1, a cryptic plasmid isolated from Lactobacillus acidipiscis and comparative analysis with its related plasmids.

    Science.gov (United States)

    Asteri, Ioanna-Areti; Papadimitriou, Konstantinos; Boutou, Effrossyni; Anastasiou, Rania; Pot, Bruno; Vorgias, Constantinos E; Tsakalidou, Effie

    2010-07-15

    The pLAC1 plasmid of Lactobacillus acidipiscis ACA-DC 1533, a strain isolated from traditional Kopanisti cheese, was characterised. Nucleotide sequence analysis revealed a circular molecule of 3478bp with a G+C content of 37.2%. Ab initio annotation indicated four putative open reading frames (orfs). orf1 and orf4 were found to encode a replication initiation protein (Rep) and a mobilization protein (Mob), respectively. The deduced products of orf2 and orf3 revealed no significant homology to other known proteins. However, in silico examination of the plasmid sequence supported the existence of a novel operon that includes rep, orf2 and orf3 in pLAC1 and that this operon is highly conserved also in plasmids pLB925A02, pSMA23, pLC88 and pC7. RT-PCR experiments allowed us to verify that these three genes are co-transcribed as a single polycistronic mRNA species. Furthermore, phylogenetic analysis of pLAC1 Rep and Mob proteins demonstrated that they may have derived from different plasmid origins, suggesting that pLAC1 is a product of a modular evolution process. Comparative analysis of full length nucleotide sequences of pLAC1 and related Lactobacillus plasmids showed that pLAC1 shares a very similar replication backbone with pLB925A02, pSMA23 and pLC88. In contrast, mob of pLAC1 was almost identical with the respective gene of plasmids pLAB1000, pLB4 and pPB1. These findings lead to the conclusion that pLAC1 acquired mob probably via an ancestral recombination event. Our overall work highlights the importance of characterizing plasmids deriving from non-starter 'wild' isolates in order to better appreciate plasmid divergence and evolution of lactic acid bacteria. 2010 Elsevier B.V. All rights reserved.

  19. A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions

    International Nuclear Information System (INIS)

    Cupples, C.G.; Miller, J.H.

    1989-01-01

    We describe the construction of six strains of Escherichia coli with different mutations at the same coding position in the lacZ gene, which specifies the active site glutamic acid residue at position 461 in beta'-galactosidase. Each strain is Lac- and reverts to Lac+ only by restoring the glutamic acid codon. The strains have been designed so that each reverts via one of the six base substitutions. The set of strains allows detection of each transition and transversion simply by monitoring the Lac- to Lac+ frequency, as demonstrated here with characterized mutagens and mutator alleles. These strains are useful for rapidly determining the mutagenic specificity of mutagens at a single site, for detecting low levels of stimulation of certain base substitutions, for monitoring specific base changes in response to various experimental conditions or strain backgrounds, and for isolating new mutator strains

  20. Qualite bio-ecologique d'un milieu lacustre hyper-eutrophisee en ...

    African Journals Online (AJOL)

    Dr AJEAGAH

    L'observation des cellules phyto-planctoniques est faite au microscope Motic de type B1 Séries ..... du Lac de Bè. Rapport préliminaire suivi de la qualité des Eaux. ... [30] - A. COUTE, & A. ILTIS, Etude au microscope électronique à balayage de ... [40] - S. SANE, Contrôle environnemental de la production primaire du lac de ...

    1. Origami ile Matematik Öğretimi/Teaching Mathematic With Origami

      OpenAIRE

      Polat, Seyat

      2013-01-01

      Özet Bu çalışmada; origami etkinliklerinin matematik dersinde kullanılması ile ilgili olarak, origaminin ilişkili olduğu konular, origami uygulamaları ile ilgili öğrenci görüşleri, origami yapılırken en çok zorlanılan şekiller ve origami uygulamaları sürecinde öğrenciler için görselleşen terimler incelenmiştir. Nitel olarak desenlenen çalışma ilköğretim 4 ve 5. sınıfa devam eden 17 öğrenciyle gerçekleştirilmiştir. Veriler yarı yapılandırılmış görüşme yöntemiyle toplanmıştır. Elde edilen bulgu...

    2. USING THE METHODS OF WAVELET ANALYSIS AND SINGULAR SPECTRUM ANALYSIS IN THE STUDY OF RADIO SOURCE BL LAC

      OpenAIRE

      Donskykh, G. I.; Ryabov, M. I.; Sukharev, A. I.; Aller, M.

      2014-01-01

      We investigated the monitoring data of extragalactic source BL Lac. This monitoring was held withUniversityofMichigan26-meter radio  telescope. To study flux density of extragalactic source BL Lac at frequencies of 14.5, 8 and 4.8 GHz, the wavelet analysis and singular spectrum analysis were used. Calculating the integral wavelet spectra allowed revealing long-term  components  (~7-8 years) and short-term components (~ 1-4 years) in BL Lac. Studying of VLBI radio maps (by the program Mojave) ...

    3. Polyester kumaşların indigo boyar maddeleri ile boyanabilirliğinin geliştirilmesi için poli(Vinil Alkol) ve modifiye poli(Vinil Alkol) polimerleri ile modifiye edilmesi

      OpenAIRE

      KALKAN ERDOĞAN, Meryem

      2017-01-01

      Bu çalışmada, tekstil sanayiinde önemli sentetik liflerden olan poli(etilen teraftalat) (PET) esaslı polyester (PES) kumaşların, indigo boyarmaddesi ile pamuklu denim (kot) kumaşlara benzer şekilde yüzeysel ve kesintisiz olarak soğukta boyanabilmesi amacıyla, poli(vinil alkol) (PVA) ve farklı bileşimlerde sentezlenen modifiye PVA (M-PVA) polimerlerini kullanarak fiziksel ve kimyasal yöntemler ile modifikasyonu gerçekleştirildi. M-PVA polimerleri, PVA varlığında glisidil metakrilat (G...

    4. The clean development mechanism (CDM) an international perspective and implications for the LAC region

      International Nuclear Information System (INIS)

      2004-08-01

      This paper addresses activity a) an analysis of international CDM experiences and its potential contribution to the LAC region. The paper begins with a section describing the basic principles of the CDM and retrieves the lessons learned from the first two years of the CDM operation. This is followed by a more detailed review in section 2 of the on-going baseline and monitoring methodology approval process. In section 3, the development value of the CDM is explored. Section 4 describes the current CDM markets, while section 5 reviews the response of host countries to the CDM outside the LAC region. Section 6 describes the various capacity building programs established by Annex 1 countries to support the CDM. In each of the first 6 sections, implications for the LAC region are identified. Section 7 brings these conclusions together into a concise summary. (The author)

    5. Lipofection of rabbit chondrocytes and long lasting expression of a lacZ reporter system in alginate beads.

      Science.gov (United States)

      Stöve, J; Fiedler, J; Huch, K; Günther, K-P; Puhl, W; Brenner, R

      2002-03-01

      Our aim was to investigate the maintenance of the transfection status of non-viral transfected chondrocytes in an alginate culture system. Chondrocytes harvested from rabbit knees were isolated by sequential digestion and cultivated in monolayer culture. At 60-70% cell density, chondrocytes were transfected with different transfection systems (FuGENE6, CaCl2, Lipofectin). A lac Z expression vector (pcDNA 3.1/Myc-His+ lacZ) was used as a reporter system. In order to improve transfection rates, hyaluronidase (4 U/ml) was used prior and during the transfection procedure. Thereafter, transfected cells were either kept in monolayer culture or embedded in alginate beads and kept in culture for up to the next 30 weeks. Transfection efficiency was maximal using FuGENE6TM/DNA at a ratio of 3:2 and hyaluronidase (4 U/ml). Transfection efficiency reached up to 40.8% (+/- 3.2%) after 36 h. In alginate beads lac Z positive cells declined to 8.5% +/- 3.3% after 4 weeks and to 4.6% +/- 3.2% after 12 weeks of culturing. After 30 weeks 3% of chondrocytes still expressed lac Z. In contrast, during culturing in monolayer, no lac Z expression was detectable after 4 weeks. Differentiation status of the chondrocytes was confirmed by histology and immunohistochemistry methods. After successful gene transfer to rabbit chondrocytes the alginate system made it possible to culture lipofected chondrocytes phenotypically stable. Genetically engineered chondrocytes express the lac Z reporter gene over a period of at least 30 weeks. This transfection and culture system provides a promising tool to further investigate the over-expression of growth factors and enzyme inhibitors. Copyright 2002 OsteoArthritis Research Society International.

    6. Male Involvement in Family Planning Decision Making in Ile-Ife ...

      African Journals Online (AJOL)

      This study assessed men's awareness, attitude, and practice of modern contraceptive methods, determined the level of spousal communication, and investigated the correlates of men's opinion in family planning decision making in Ile-Ife, Nigeria. Quantitative methodology was employed in this cross-sectional descriptive ...

    7. Groundwater contamination in the basement-complex area of Ile-Ife, southwestern Nigeria: A case study using the electrical-resistivity geophysical method

      Science.gov (United States)

      Adepelumi, A. A.; Ako, B. D.; Ajayi, T. R.

      2001-11-01

      Hydrogeoenvironmental studies were carried out at the sewage-disposal site of Obafemi Awolowo University campus, Ile-Ife, Nigeria. The objective of the survey was to determine the reliability of the electrical-resistivity method in mapping pollution plumes in a bedrock environment. Fifty stations were occupied with the ABEM SAS 300C Terrameter using the Wenner array. The electrical-resistivity data were interpreted by a computer-iteration technique. Water samples were collected at a depth of 5.0 m in 20 test pits and analyzed for quality. The concentrations of Cr, Cd, Pb, Zn, and Cu are moderately above the World Health Organization recommended guidelines. Plumes of contaminated water issuing from the sewage ponds were delineated. The geoelectric sections reveal four subsurface layers, with increasing depth, lateritic clay, clayey sand/sand, and weathered/fractured bedrock, and fresh bedrock. The deepest layers, 3 and 4, constitute the main aquifer, which has a thickness of 3.1-67.1 m. The distribution of the elements in the sewage effluent confirms a hydrological communication between the disposal ponds and groundwater. The groundwater is contaminated, as shown by sampling and the geophysical results. Thus, the results demonstrate the reliability of the direct-current electrical-resistivity geophysical method in sensing and mapping pollution plumes in a crystalline bedrock environment. Résumé. Des études géo-environnementales ont été réalisées sur le site d'épandages du campus universitaire d'Obafemi Awolowo, à Ile-Ife (Nigeria). L'objectif de ce travail était de déterminer la fiabilité de la méthode des résistivités électriques pour cartographier les panaches de pollution dans un environnement de socle. Cinquante stations ont été soumises à mesures au moyen d'un ABEM SAS 300C Terrameter en utilisant le dispositif de Wenner. Les données de résistivité électrique ont été interprétées au moyen d'une technique de calcul itérative. Des

    8. Butterfly diversity in Obafemi Awolowo University, Ile Ife, South-west ...

      African Journals Online (AJOL)

      Butterfly diversity on Obafemi Awolowo University, Ile Ife, was investigated by the use of sweep nets along transects in different sites. The sites include; Parks and Gardens, Zoological Garden, Oxidation Pond, Botanical Garden, Teaching and Research Farm, New Bukkateria and open fields. Data was analyzed with ...

    9. Exploring the sequence-function relationship in transcriptional regulation by the lac O1 operator.

      Science.gov (United States)

      Maity, Tuhin S; Jha, Ramesh K; Strauss, Charlie E M; Dunbar, John

      2012-07-01

      Understanding how binding of a transcription factor to an operator is influenced by the operator sequence is an ongoing quest. It facilitates discovery of alternative binding sites as well as tuning of transcriptional regulation. We investigated the behavior of the Escherichia coli Lac repressor (LacI) protein with a large set of lac O(1) operator variants. The 114 variants examined contained a mean of 2.9 (range 0-4) mutations at positions -4, -2, +2 and +4 in the minimally required 17 bp operator. The relative affinity of LacI for the operators was examined by quantifying expression of a GFP reporter gene and Rosetta structural modeling. The combinations of mutations in the operator sequence created a wide range of regulatory behaviors. We observed variations in the GFP fluorescent signal among the operator variants of more than an order of magnitude under both uninduced and induced conditions. We found that a single nucleotide change may result in changes of up to six- and 12-fold in uninduced and induced GFP signals, respectively. Among the four positions mutated, we found that nucleotide G at position -4 is strongly correlated with strong repression. By Rosetta modeling, we found a significant correlation between the calculated binding energy and the experimentally observed transcriptional repression strength for many operators. However, exceptions were also observed, underscoring the necessity for further improvement in biophysical models of protein-DNA interactions. © 2012 The Authors Journal compilation © 2012 FEBS.

    10. Effector Overlap between the lac and mel Operons of Escherichia coli: Induction of the mel Operon with β-Galactosides.

      Science.gov (United States)

      Narang, Atul; Oehler, Stefan

      2017-05-01

      The lac (lactose) operon (which processes β-galactosides) and the mel (melibiose) operon (which processes α-galactosides) of Escherichia coli have a close historical connection. A number of shared substrates and effectors of the permeases and regulatory proteins have been reported over the years. Until now, β-thiogalactosides like TMG (methyl-β-d-thiogalactopyranoside) and IPTG (isopropyl-β-d-thiogalactopyranoside) have not generally been considered to be inducers of the mel operon. The same is true for β-galactosides such as lactose [β-d-galactopyranosyl-(1→4)-d-glucose], which is a substrate but is not itself an inducer of the lac operon. This report shows that all three sugars can induce the mel operon significantly when they are accumulated in the cell by Lac permease. Strong induction by β-thiogalactosides is observed in the presence of Lac permease, and strong induction by lactose (more than 200-fold) is observed in the absence of β-galactosidase. This finding calls for reevaluation of TMG uptake experiments as assays for Lac permease that were performed with mel + strains. IMPORTANCE The typical textbook picture of bacterial operons is that of stand-alone units of genetic information that perform, in a regulated manner, well-defined cellular functions. Less attention is given to the extensive interactions that can be found between operons. Well-described examples of such interactions are the effector molecules shared by the lac and mel operons. Here, we show that this set has to be extended to include β-galactosides, which have been, until now, considered not to effect the expression of the mel operon. That they can be inducers of the mel operon as well as the lac operon has not been noted in decades of research because of the Escherichia coli genetic background used in previous studies. Copyright © 2017 American Society for Microbiology.

    11. 76 FR 68124 - Television Broadcasting Services; Fond du Lac, WI

      Science.gov (United States)

      2011-11-03

      ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 09-115, RM-11543; DA 11-1502] Television Broadcasting Services; Fond du Lac, WI AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: In this document, the Commission denies a petition for reconsideration of an August 12...

    12. Enterovirus infections in hospitals of Ile de France region over 2013.

      Science.gov (United States)

      Molet, Lucie; Saloum, Kenda; Marque-Juillet, Stéphanie; Garbarg-Chenon, Antoine; Henquell, Cécile; Schuffenecker, Isabelle; Peigue-Lafeuille, Hélène; Rozenberg, Flore; Mirand, Audrey

      2016-01-01

      The monitoring and genotyping of Enterovirus (EV) infections can help to associate particular or severe clinical manifestations with specific EV types and to identify the aetiology of infectious outbreaks. To describe the epidemiological features of EV infections diagnosed during the year 2013 in the Greater Paris area (Ile de France). During 2013, 2497 samples taken from 470 patients in 33 hospitals of Ile-de France were tested for EV genome by RT-PCR. EV genotyping was performed by the National Reference Centre (NRC) laboratories. EV infections were retrospectively reviewed by retrieving clinical and genotyping data from the NRC database. Of the 2497 samples, 490 (19.6%) was positive for EV genome detection. These EV infections represented 88.7% and 24.1%, respectively, of all reported regional and national infections. Twenty-seven different genotypes were identified. Echovirus 30 (E-30) accounted for 54.1% of all characterized strains and caused a large outbreak. Four severe neonatal infections were reported, of which two were caused by EV-A71. Respiratory infections involving EV-D68 were observed in two adults. One fatal case of Coxsackievirus A2-associated myocarditis was reported. Monitoring EV infections in combination with EV genotyping via the French EV network characterized the epidemiology of EV infections in the Ile de France region in 2013 and documented severe EV infections associated with EV-A71 or CV-A2. Copyright © 2015 Elsevier B.V. All rights reserved.

    13. The protein C omega-loop substitution Asn2Ile is associated with reduced protein C anticoagulant activity.

      LENUS (Irish Health Repository)

      Preston, Roger J S

      2012-02-01

      We report a kindred with heritable protein C (PC) deficiency in which two siblings with severe thrombosis showed a composite type I and IIb PC deficiency phenotype, identified using commercial PC assays (proband: PC antigen 42 u\\/dl, amidolytic activity 40 u\\/dl, anticoagulant activity 9 u\\/dl). The independent PROC nucleotide variations c.669C>A (predictive of Ser181Arg) and c.131C>T (predictive of Asn2Ile) segregated with the type I and type IIb PC deficiency phenotypes respectively, but co-segregated in the siblings with severe thrombosis. Soluble thrombomodulin (sTM)-mediated inhibition of plasma thrombin generation from an individual with PC-Asn2Ile was lower (endogenous thrombin potential (ETP) 56 +\\/- 1% that of ETP determined without sTM) than control plasma (ETP 15 +\\/- 2%) indicating reduced PC anticoagulant activity. Recombinant APC-Asn2Ile exhibited normal amidolytic activity but impaired anticoagulant activity. Protein S (PS)-dependent anticoagulant activity of recombinant APC-Asn2Ile and binding of recombinant APC-Asn2Ile to endothelial protein C receptor (EPCR) were reduced compared to recombinant wild-type APC. Asn2 lies within the omega-loop of the PC\\/APC Gla domain and this region is critical for calcium-induced folding and subsequent interactions with anionic phospholipids, EPCR and PS. The disruption of these interactions in this naturally-occurring PC variant highlights their collective importance in mediating APC anticoagulant activity in vivo.

    14. Influence of salt content and processing time on sensory characteristics of cooked "lacón".

      Science.gov (United States)

      Purriños, Laura; Bermúdez, Roberto; Temperán, Sara; Franco, Daniel; Carballo, Javier; Lorenzo, José M

      2011-04-01

      The influence of salt content and processing time on the sensory properties of cooked "lacón" were determined. "Lacón" is a traditional dry-cured and ripened meat product made in the north-west of Spain from the fore leg of the pig, following a similar process to that of dry-cured ham. Six batches of "lacón" were salted with different amounts of salt (LS (3 days of salting), MS (4 days of salting) and HS (5 days of salting)) and ripened during two times (56 and 84 days of dry-ripening). Cured odour in all batches studied, red colour and rancid odour in MS and HS batches, flavour intensity in MS batch and fat yellowness, rancid flavour and hardness in the HS batch were significantly different with respect to the time of processing. Appearance, odour, flavour and texture were not significantly affected by the salt content (P>0.05). However, the saltiness score showed significant differences with respect to the salt levels in all studied batches (56 and 84 days of process). The principal component analysis showed that physicochemical traits were the most important ones concerning the quality of dry-cured "lacón" and offered a good separation of the mean samples according to the dry ripening days and salt level. © 2010 The American Meat Science Association. Published by Elsevier Ltd. All rights reserved.

    15. Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors

      Science.gov (United States)

      Ou, Hong-Yu; Kuang, Shan N.; He, Xinyi; Molgora, Brenda M.; Ewing, Peter J.; Deng, Zixin; Osby, Melanie; Chen, Wangxue; Xu, H. Howard

      2015-01-01

      Acinetobacter baumannii is an important human pathogen due to its multi-drug resistance. In this study, the genome of an ST10 outbreak A. baumannii isolate LAC-4 was completely sequenced to better understand its epidemiology, antibiotic resistance genetic determinants and potential virulence factors. Compared with 20 other complete genomes of A. baumannii, LAC-4 genome harbors at least 12 copies of five distinct insertion sequences. It contains 12 and 14 copies of two novel IS elements, ISAba25 and ISAba26, respectively. Additionally, three novel composite transposons were identified: Tn6250, Tn6251 and Tn6252, two of which contain resistance genes. The antibiotic resistance genetic determinants on the LAC-4 genome correlate well with observed antimicrobial susceptibility patterns. Moreover, twelve genomic islands (GI) were identified in LAC-4 genome. Among them, the 33.4-kb GI12 contains a large number of genes which constitute the K (capsule) locus. LAC-4 harbors several unique putative virulence factor loci. Furthermore, LAC-4 and all 19 other outbreak isolates were found to harbor a heme oxygenase gene (hemO)-containing gene cluster. The sequencing of the first complete genome of an ST10 A. baumannii clinical strain should accelerate our understanding of the epidemiology, mechanisms of resistance and virulence of A. baumannii. PMID:25728466

    16. The REX survey as a tool to test the beaming model for BL Lacs

      CERN Document Server

      Caccianiga, A; MacCacaro, T; Wolter, A; Gioia, I M

      1999-01-01

      In the context of the beaming model (BM) BL Lac and FR I radio galaxies are thought to be the same class of sources seen at different angles. If this picture is correct, we expect to find some transition objects with intermediate properties between the two classes. To date, this intermediate population of objects is missing, probably due to the limiting fluxes of the current X-ray/radio surveys and/or to the criteria used to separate BL Lacs from normal elliptical galaxies. As pointed out by Browne and Marcha (1993), the detection of the transition objects requires particular attention since the "weak" BL Lac nucleus is hidden by the light of the host elliptical galaxy. A useful criterion often used to assess the presence of a non-thermal source, in addition to the stellar emission of the host galaxy, is the Ca contrast at 4000 AA (K/sub 4000/). This quantity, which is defined as the relative depression of the spectrum across 4000 AA, is a typical feature observed in a "normal" elliptical galaxy; the samples ...

    17. Constraining the red shifts of TeV BL Lac objects

      Science.gov (United States)

      Qin, Longhua; Wang, Jiancheng; Yan, Dahai; Yang, Chuyuan; Yuan, Zunli; Zhou, Ming

      2018-01-01

      We present a model-dependent method to estimate the red shifts of three TeV BL Lac objects (BL Lacs) through fitting their (quasi-)simultaneous multi-waveband spectral energy distributions (SEDs) with a one-zone leptonic synchrotron self-Compton model. Considering the impact of electron energy distributions (EEDs) on the results, we use three types of EEDs to fit the SEDs: a power-law EED with exponential cut-off (PLC), a log-parabola (PLLP) EED and the broken power-law (BPL) EED. We also use a parameter α to describe the uncertainties of the extragalactic background light models, as in Abdo et al. We then use a Markov chain Monte Carlo method to explore the multi-dimensional parameter space and obtain the uncertainties of the model parameters based on the observational data. We apply our method to obtain the red shifts of three TeV BL Lac objects in the marginalized 68 per cent confidence, and find that the PLC EED does not fit the SEDs. For 3C66A, the red shift is 0.14-0.31 and 0.16-0.32 in the BPL and PLLP EEDs. For PKS1424+240, the red shift is 0.55-0.68 and 0.55-0.67 in the BPL and PLLP EEDs. For PG1553+113, the red shift is 0.22-0.48 and 0.22-0.39 in the BPL and PLLP EEDs. We also estimate the red shift of PKS1424+240 in the high stage to be 0.46-0.67 in the PLLP EED, roughly consistent with that in the low stage.

    18. Infrared polarimetry and photometry of BL Lac objects

      International Nuclear Information System (INIS)

      Impey, C.D.; Williams, P.M.

      1984-01-01

      Photometry and polarimetry in the JHK wavebands have now been obtained for 25 BL Lac objects. Several new objects have been monitored for periods of up to five days, and accumulated data is sufficient for a statistical analysis of polarization properties. The selection effects operating on this sample are examined first. A power-law spectrum is consistent with the spectra of all but three objects. A number of important new results are reported. (author)

    19. Introductions de nouvelles espèces de poissons dans les eaux douces tropicales : objectifs et conséquences

      Directory of Open Access Journals (Sweden)

      LÉVÊQUE C.

      1997-01-01

      Full Text Available Les introductions d'espèces dans les milieux aquatiques tropicaux ont d'abord eu pour motivation de développer la pêche sportive pour les émigrants européens. Actuellement, les principaux objectifs sont d'améliorer la pêche artisanale locale et de développer l'aquaculture. L'introduction de poissons pélagiques de la famille des clupéidés dans divers lacs naturels ou de barrage apparaît comme un succès, car elle a permis de développer la pêche de manière significative, sans dommages apparents pour la faune indigène. Par contre, l'introduction de prédateurs a toujours eu des conséquences négatives sur la faune autochtone, et divers exemples sont donnés dont la truite (Salmo trutta Linnaeus, 1758 en Australie et dans le lac Titicaca, et le capitaine (Lates niloticus Linnaeus, 1758 dans le lac Victoria. Les introductions de tilapias donnent lieu à des bilans plus mitigés, généralement positifs lorsque les cichlidés sont introduits dans des milieux pauvres en espèces autochtones, alors que des disparitions d'espèces ont été constatées pour les introductions réalisées dans les milieux déjà riches en espèces. L'exemple des lacs malgaches montre les conséquences d'introductions successives de diverses espèces sur la faune ichtyologique et la pêche.

    20. Transformation of lacZ using different promoters in the commercially ...

      African Journals Online (AJOL)

      Yomi

      2012-01-26

      Jan 26, 2012 ... forced growth under unnatural conditions. In order to ... yezoensis include the gluc, cat, GUS and GFP genes. (Cheney et al. ... bacterial lacZ gene encodes the β-galactosidase enzyme which is capable of .... Table 1. Effect of viral promoters on transient β-galactosidase activity in microparticle bombarded G.

    1. Assessment Of School Library Services In Ile-Luji/Okeigbo Local ...

      African Journals Online (AJOL)

      The paper carried out the analysis of the library collection, staffing, building space and furniture of Ile-oluji/Okeigbo Local Government Area, Ondo State. The evaluation was based on the “Ondo State Library Board for Schools Standard”. Findings from the research showed that these school libraries were yet to achieve any ...

    2. The Sedentary Multi-Frequency Survey. I. Statistical Identification and Cosmological Properties of HBL BL Lacs

      OpenAIRE

      Giommi, P.; Menna, M. T.; Padovani, P.

      1999-01-01

      We have assembled a multi-frequency database by cross-correlating the NVSS catalog of radio sources with the RASSBSC list of soft X-ray sources, obtaining optical magnitude estimates from the Palomar and UK Schmidt surveys as provided by the APM and COSMOS on-line services. By exploiting the nearly unique broad-band properties of High-Energy Peaked (HBL) BL Lacs we have statistically identified a sample of 218 objects that is expected to include about 85% of BL Lacs and that is therefore seve...

    3. Hydrogeologic characteristics of domains of sparsely fractured rock in the granitic Lac Du Bonnet Batholith, southeastern Manitoba, Canada

      International Nuclear Information System (INIS)

      Stevenson, D.R.; Kozak, E.T.; Davison, C.C.; Gascoyne, M.; Broadfoot, R.A.

      1996-06-01

      The hydrogeologic characteristics of the granitic Lac du Bonnet batholith in southeastern Manitoba have been studied since 1978, as part of AECL's program to assess the concept of disposing of Canada's nuclear fuel waste deep within plutonic rocks of the Canadian Shield (Davison et al. 1994a). These studies have included an extensive program of drilling, logging, testing, sampling and monitoring in 19 deep surface boreholes drilled at Grid areas located across the Lac du Bonnet batholith, at the Whiteshell Laboratory (WL), and in surface and underground boreholes at the Underground Research Laboratory (URL). Based on these investigations domains of low permeability, sparsely fractured rock (SFR) have been identified in the Lac du Bonnet batholith

    4. The Active Jasmonate JA-Ile Regulates a Specific Subset of Plant Jasmonate-Mediated Resistance to Herbivores in Nature

      Directory of Open Access Journals (Sweden)

      Meredith C. Schuman

      2018-06-01

      Full Text Available The jasmonate hormones are essential regulators of plant defense against herbivores and include several dozen derivatives of the oxylipin jasmonic acid (JA. Among these, the conjugate jasmonoyl isoleucine (JA-Ile has been shown to interact directly with the jasmonate co-receptor complex to regulate responses to jasmonate signaling. However, functional studies indicate that some aspects of jasmonate-mediated defense are not regulated by JA-Ile. Thus, it is not clear whether JA-Ile is best characterized as the master jasmonate regulator of defense, or if it regulates more specific aspects. We investigated possible functions of JA-Ile in anti-herbivore resistance of the wild tobacco Nicotiana attenuata, a model system for plant-herbivore interactions. We first analyzed the soluble and volatile secondary metabolomes of irJAR4xirJAR6, asLOX3, and WT plants, as well as an RNAi line targeting the jasmonate co-receptor CORONATINE INSENSITIVE 1 (irCOI1, following a standardized herbivory treatment. irJAR4xirJAR6 were the most similar to WT plants, having a ca. 60% overlap in differentially regulated metabolites with either asLOX3 or irCOI1. In contrast, while at least 25 volatiles differed between irCOI1 or asLOX3 and WT plants, there were few or no differences in herbivore-induced volatile emission between irJAR4xirJAR6 and WT plants, in glasshouse- or field-collected samples. We then measured the susceptibility of jasmonate-deficient vs. JA-Ile-deficient plants in nature, in comparison to wild-type (WT controls, and found that JA-Ile-deficient plants (irJAR4xirJAR6 are much better defended even than a mildly jasmonate-deficient line (asLOX3. The differences among lines could be attributed to differences in damage from specific herbivores, which appeared to prefer either one or the other jasmonate-deficient phenotype. We further investigated the elicitation of one herbivore-induced volatile known to be jasmonate-regulated and to mediate resistance to

    5. [Fond du Lac archeological resources within the Draft Area Recommendation Report

      International Nuclear Information System (INIS)

      Danz, D.L.

      1986-01-01

      Research into archaeological resources of the Fond du Lac Band within the DOE proposed high-level nuclear waste sites resulted in the discovery of four traditional ancestral sites. A number of ancestral sites that are located within other proposed repository sites were also discovered

    6. Modeling and experimental assessment of a buried Leu–Ile mutation in dengue envelope domain III

      Energy Technology Data Exchange (ETDEWEB)

      Kulkarni, Manjiri R. [Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16, Nakamachi, Koganei-shi, Tokyo, 184-8588 (Japan); Numoto, Nobutaka; Ito, Nobutoshi [Department of Structural Biology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima Bunkyo-ku, Tokyo, 113-8510 (Japan); Kuroda, Yutaka, E-mail: ykuroda@cc.tuat.ac.jp [Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16, Nakamachi, Koganei-shi, Tokyo, 184-8588 (Japan)

      2016-02-26

      Envelope protein domain III (ED3) of the dengue virus is important for both antibody binding and host cell interaction. Here, we focused on how a L387I mutation in the protein core could take place in DEN4 ED3, but cannot be accommodated in DEN3 ED3 without destabilizing its structure. To this end, we modeled a DEN4-L387I structure using the Penultimate Rotamer Library and taking the DEN4 ED3 main-chain as a fixed template. We found that three out of seven Ile{sup 387} conformers fit in DEN4 ED3 without introducing the severe atomic clashes that are observed when DEN3 serotype’s ED3 is used as a template. A more extensive search using 273 side-chain rotamers of the residues surrounding Ile{sup 387} confirmed this prediction. In order to assess the prediction, we determined the crystal structure of DEN4-L387I at 2 Å resolution. Ile{sup 387} indeed adopted one of the three predicted rotamers. Altogether, this study demonstrates that the effects of single mutations are to a large extent successfully predicted by systematically modeling the side-chain structures of the mutated as well as those of its surrounding residues using fixed main-chain structures and assessing inter-atomic steric clashes. More accurate and reliable predictions require considering sub-angstrom main-chain deformation, which remains a challenging task. - Highlights: • We mutated L387I of DEN4 ED3 and examined its effects on structure and stability. • We modeled the side-chain of Ile{sup 387} using DEN4 ED3's structure as a template. • We determined the crystal structure of DEN4-L387I and confirmed the modeling. • Side-chain repacking occurring around Ile{sup 387} involved >3 inter-connected residues. • These results explained why L387I mutation in DEN4 ED3 conserves thermostability.

    7. Modeling and experimental assessment of a buried Leu–Ile mutation in dengue envelope domain III

      International Nuclear Information System (INIS)

      Kulkarni, Manjiri R.; Numoto, Nobutaka; Ito, Nobutoshi; Kuroda, Yutaka

      2016-01-01

      Envelope protein domain III (ED3) of the dengue virus is important for both antibody binding and host cell interaction. Here, we focused on how a L387I mutation in the protein core could take place in DEN4 ED3, but cannot be accommodated in DEN3 ED3 without destabilizing its structure. To this end, we modeled a DEN4-L387I structure using the Penultimate Rotamer Library and taking the DEN4 ED3 main-chain as a fixed template. We found that three out of seven Ile"3"8"7 conformers fit in DEN4 ED3 without introducing the severe atomic clashes that are observed when DEN3 serotype’s ED3 is used as a template. A more extensive search using 273 side-chain rotamers of the residues surrounding Ile"3"8"7 confirmed this prediction. In order to assess the prediction, we determined the crystal structure of DEN4-L387I at 2 Å resolution. Ile"3"8"7 indeed adopted one of the three predicted rotamers. Altogether, this study demonstrates that the effects of single mutations are to a large extent successfully predicted by systematically modeling the side-chain structures of the mutated as well as those of its surrounding residues using fixed main-chain structures and assessing inter-atomic steric clashes. More accurate and reliable predictions require considering sub-angstrom main-chain deformation, which remains a challenging task. - Highlights: • We mutated L387I of DEN4 ED3 and examined its effects on structure and stability. • We modeled the side-chain of Ile"3"8"7 using DEN4 ED3's structure as a template. • We determined the crystal structure of DEN4-L387I and confirmed the modeling. • Side-chain repacking occurring around Ile"3"8"7 involved >3 inter-connected residues. • These results explained why L387I mutation in DEN4 ED3 conserves thermostability.

    8. 1886-IJBCS-Article-Barnabas Kayalto

      African Journals Online (AJOL)

      hp

      espèces de poissons, des sédiments et des eaux du Lac Tchad. Barnabas .... Des poissons. L'échantillonnage était fait au bord du ..... craindre. Tableau 1 : Teneur en métaux lourds des eaux, en ppm (mg/L), moyenne ± écart-type par.

    9. Radiocarbon measurements at LAC-UFF: Recent performance

      Energy Technology Data Exchange (ETDEWEB)

      Linares, Roberto, E-mail: rlinares@if.uff.br [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil); Macario, Kita D. [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil); Santos, Guaciara M. [Earth System Science, University of California, Irvine, B321 Croul Hall, Irvine, CA 92697-3100 (United States); Carvalho, Carla [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil); Departamento de Geoquímica, Universidade Federal Fluminense, Outeiro São João Batista, s/n, Niterói 24020-141 (Brazil); Santos, Hellen C. dos; Gomes, Paulo R.S.; Castro, Maikel D.; Oliveira, Fabiana M.; Alves, Eduardo Q. [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil)

      2015-10-15

      In 2012 a single stage accelerator mass spectrometer from NEC was installed at the Radiocarbon Laboratory of Universidade Federal Fluminense (LAC-UFF), Niterói, Brazil. Here, we present a status report of our facility. We discuss some modifications applied to our combustion protocol in an attempt to reduce our procedural blank, mostly to processed organic samples. Measurements of reference materials indicate low precision and accuracy that are partially related to beam optics through the acceleration tube. We observed that once the beam current intensity increases the measured {sup 13}C{sup +}/{sup 12}C{sup +} becomes erratic. Therefore, in order to maintain the AMS-δ{sup 13}C values within reasonable values, so that fractionation corrections using the spectrometer {sup 13}C{sup +}/{sup 12}C{sup +} values does not affect the final {sup 14}C results, we are forced to limit the {sup 12}C{sup −} beam intensity to ⩽30 μA. This requirement was confirmed during our accuracy tests, when measuring selected annual tree-rings wood samples from a Parana pine (Araucaria angustifolia) between 1927 and 1997 previously measured at the Keck Carbon Cycle AMS Facility (KCCAMS), at the University of California, Irvine (UCI). At the LAC-UFF tree-ring wood samples were processed and measured in 4 different batches during a period of about 5 months. The {sup 14}C results were later compared to the high-precision data obtained at KCCAMS/UCI and reached a good agreement. Recently a problem associated with graphitization yield were finally identified and new measurements with secondary standards are promising.

    10. Dynamics and bistability in a reduced model of the lac operon

      Science.gov (United States)

      Yildirim, Necmettin; Santillán, Moisés; Horike, Daisuke; Mackey, Michael C.

      2004-06-01

      It is known that the lac operon regulatory pathway is capable of showing bistable behavior. This is an important complex feature, arising from the nonlinearity of the involved mechanisms, which is essential to understand the dynamic behavior of this molecular regulatory system. To find which of the mechanisms involved in the regulation of the lac operon is the origin of bistability, we take a previously published model which accounts for the dynamics of mRNA, lactose, allolactose, permease and β-galactosidase involvement and simplify it by ignoring permease dynamics (assuming a constant permease concentration). To test the behavior of the reduced model, three existing sets of data on β-galactosidase levels as a function of time are simulated and we obtain a reasonable agreement between the data and the model predictions. The steady states of the reduced model were numerically and analytically analyzed and it was shown that it may indeed display bistability, depending on the extracellular lactose concentration and growth rate.

    11. NEW HIGH- z FERMI BL LACS WITH THE PHOTOMETRIC DROPOUT TECHNIQUE

      Energy Technology Data Exchange (ETDEWEB)

      Kaur, A.; Ajello, M.; Hartmann, D. H.; Paliya, V. S. [Department of Physics and Astronomy, Clemson University, SC 29634-0978 (United States); Rau, A.; Greiner, J.; Bolmer, J.; Schady, P. [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstraße 1, D-85748 Garching (Germany); Domínguez, A., E-mail: akaur@g.clemson.edu [Grupo de Altas Energías, Universidad Complutense, E-28040 Madrid (Spain)

      2017-01-01

      Determining redshifts for BL Lacertae (BL Lac) objects using the traditional spectroscopic method is challenging due to the absence of strong emission lines in their optical spectra. We employ the photometric dropout technique to determine redshifts for this class of blazars using the combined 13 broadband filters from Swift -UVOT and the multi-channel imager GROND at the MPG 2.2 m telescope at ESO's La Silla Observatory. The wavelength range covered by these 13 filters extends from far-ultraviolet to the near-infrared. We report results on 40 new Fermi- detected BL Lacs with the photometric redshift determinations for five sources, with 3FGL J1918.2–4110 being the most distant in our sample at z  = 2.16. Reliable upper limits are provided for 20 sources in this sample. Using the highest energy photons for these Fermi -LAT sources, we evaluate the consistency with the gamma-ray horizon due to the extragalactic background light.

    12. Computing Optical Variable Periods of BL Lac Object S5 0716+ 714 ...

      Indian Academy of Sciences (India)

      Computing Optical Variable Periods of BL Lac Object S5 0716+ 714 ... The study of long-term periodical variation is an important way to get the charac- ... continuous Fourier transform together, define a window function, and finally obtain.

    13. Kinetic proofreading at single molecular level: aminoacylation of tRNA(Ile and the role of water as an editor.

      Directory of Open Access Journals (Sweden)

      Mantu Santra

      Full Text Available Proofreading/editing in protein synthesis is essential for accurate translation of information from the genetic code. In this article we present a theoretical investigation of efficiency of a kinetic proofreading mechanism that employs hydrolysis of the wrong substrate as the discriminatory step in enzyme catalytic reactions. We consider aminoacylation of tRNA(Ile which is a crucial step in protein synthesis and for which experimental results are now available. We present an augmented kinetic scheme and then employ methods of stochastic simulation algorithm to obtain time dependent concentrations of different substances involved in the reaction and their rates of formation. We obtain the rates of product formation and ATP hydrolysis for both correct and wrong substrates (isoleucine and valine in our case, respectively, in single molecular enzyme as well as ensemble enzyme kinetics. The present theoretical scheme correctly reproduces (i the amplitude of the discrimination factor in the overall rates between isoleucine and valine which is obtained as (1.8×10(2.(4.33×10(2 = 7.8×10(4, (ii the rates of ATP hydrolysis for both Ile and Val at different substrate concentrations in the aminoacylation of tRNA(Ile. The present study shows a non-michaelis type dependence of rate of reaction on tRNA(Ile concentration in case of valine. The overall editing in steady state is found to be independent of amino acid concentration. Interestingly, the computed ATP hydrolysis rate for valine at high substrate concentration is same as the rate of formation of Ile-tRNA(Ile whereas at intermediate substrate concentration the ATP hydrolysis rate is relatively low. We find that the presence of additional editing domain in class I editing enzyme makes the kinetic proofreading more efficient through enhanced hydrolysis of wrong product at the editing CP1 domain.

    14. Trafalgar Square'ile järjekordne teos valitud / Rael Artel

      Index Scriptorium Estoniae

      Artel, Rael, 1980-

      2004-01-01

      Järgmisel kevadel paigaldatakse Trafalgar Square'ile 18 kuuks Marc Quinni 4,5 m kõrgune valgest marmorist kuju "Alison Lapper Pregnant". A. Lapper (sünd. 1965) on raske füüsilise väärarenguga kunstnik. Seejärel paigaldatakse väljakule teine finaali jõudnud skulptuur - sakslase Thomas Schütte'i "Hotel for the Birds"

    15. First inventory of the echinoderms from Juan de Nova (Iles Eparses ...

      African Journals Online (AJOL)

      Juan de Nova is one of the Iles Eparses, French islands scattered in the Mozambique Channel (Western India Ocean). They have been kept isolated of the anthropogenic influences which makes them rare areas to study biodiversity and provides elements of comparison with areas that are strongly impacted by urbanization ...

    16. Infrared polarimetry and photometry of BL Lac objects. 2

      Energy Technology Data Exchange (ETDEWEB)

      Impey, C D [Hawaii Univ., Honolulu (USA). Inst. for Astronomy; Brand, P W.J.L. [Edinburgh Univ. (UK). Dept. of Astronomy; Wolstencroft, R D [Royal Observatory, Edinburgh (UK); Williams, P M [United Kingdom Infrared Telescope Unit, Hilo, Hawaii (USA)

      1984-07-15

      Photometry and polarimetry in the JHK wavebands have now been obtained for 25 BL Lac objects. Several new objects have been monitored for periods of up to five days, and accumulated data is sufficient for a statistical analysis of polarization properties. The selection effects operating on this sample are examined first. A power-law spectrum is consistent with the spectra of all but three objects. A number of important new results are reported.

    17. A source of artifact in the lacZ reversion assay in Escherichia coli.

      Science.gov (United States)

      Hoffmann, George R; Gray, Carol L; Lange, Paulina B; Marando, Christie I

      2015-06-01

      The lacZ reversion assay in Escherichia coli measures point mutations that occur by specific base substitutions and frameshift mutations. The tester strains cannot use lactose as a carbon source (Lac(-)), and revertants are easily detected by growth on lactose medium (Lac(+)). Six strains identify the six possible base substitutions, and five strains measure +G, -G, -CG, +A and -A frameshifts. Strong mutagens give dose-dependent increases in numbers of revertants per plate and revertant frequencies. Testing compounds that are arguably nonmutagens or weakly mutagenic, we often noted statistically significant dose-dependent increases in revertant frequency that were not accompanied by an absolute increase in numbers of revertants. The increase in frequency was wholly ascribable to a declining number of viable cells owing to toxicity. Analysis of the conditions revealed that the frequency of spontaneous revertants is higher when there are fewer viable cells per plate. The phenomenon resembles "adaptive" or "stress" mutagenesis, whereby lactose revertants accumulate in Lac(-) bacteria under starvation conditions in the absence of catabolite repression. Adaptive mutation is observed after long incubation and might be expected to be irrelevant in a standard assay using 48-h incubation. However, we found that elevated revertant frequencies occur under typical assay conditions when the bacterial lawn is thin, and this can cause increases in revertant frequency that mimic chemical mutagenesis when treatments are toxic but not mutagenic. Responses that resemble chemical mutagenesis were observed in the absence of mutagenic treatment in strains that revert by different frameshift mutations. The magnitude of the artifact is affected by cell density, dilution, culture age, incubation time, catabolite repression and the age and composition of media. Although the specific reversion assay is effective for quickly distinguishing classes of mutations induced by potent mutagens, its

    18. Management of Primary Dysmenorrhea by School Adolescents in ILE-IFE, Nigeria

      Science.gov (United States)

      Ogunfowokan, Adesola A.; Babatunde, Oluwayemisi A.

      2010-01-01

      Dysmenorrhea is a problem that girls and women face and often manage themselves with or without support from health professionals. A cross-sectional, descriptive study was conducted among adolescents with dysmenorrhea (N = 150) in Ile-Ife, Nigeria. The aims of the study were to determine their knowledge of menstruation and primary dysmenorrhea,…

    19. Effets perturbateurs endocriniens des pesticides organochlores.

      Science.gov (United States)

      Charlier, C; Plomteux, G

      2002-01-01

      étabolisme glucidique et notamment d-un taux élevé de glycogène hépatique (7). Les pesticides organochlorés (DDT, DDE) entraînent également des perturbations d-ordre métabolique chez certaines espèces d-oiseaux, notamment le faucon pèlerin en Grande Bretagne et les oiseaux piscivores des grands lacs nord américains où l-on a constaté au cours des années 1960 que leur reproduction était menacée et qu-une des manifestations les plus évidentes des perturbations observées était le taux élevé de malformations (8). Des mortalités élevées de poissons ou de coquillages ont été rapportées dans des élevages situés à proximité des zones d-épandage de pesticides organophosphorés et de carbamates. En 1991, la dispersion aérienne de fenitrothion dans le but de provoquer la démoustication en Languedoc a été à l-origine de la perte de plusieurs tonnes de crevettes japonaises. L-utilisation de trichlorfon et de dichlorvos comme antiparasitaires dans des fermes d-élevages de saumons a provoqué des épisodes de mortalité importante (9).

    20. Receptor binding radiotracers for the angiotensin II receptor: radioiodinated [Sar1, Ile8]angiotensin II

      International Nuclear Information System (INIS)

      Gibson, R.E.; Beauchamp, H.T.; Fioravanti, C.; Brenner, N.; Burns, H.D.

      1994-01-01

      The potential for imaging the angiotensin II receptor was evaluated using the radioiodinated peptide antagonist [ 125 I][Sar 1 , Ile 8 ]angiotensin II. The radioligand provides a receptor-mediated signal in several tissues in rat (kidneys, adrenal and liver). The receptor-mediated signal of 3% ID/g kidney cortex should be sufficient to permit imaging, at least via SPECT. The radiotracer is sensitive to reductions in receptor concentration and can be used to define in vivo dose-occupancy curves of angiotensin II receptor ligands. Receptor-mediated images of [ 123 I][Sar 1 , Ile 8 ]angiotensin II were obtained in the rat kidney and Rhesus monkey liver. (author)

    1. Effect of the partial NaCl substitution by other chloride salts on the volatile profile during the ripening of dry-cured lacón

      Energy Technology Data Exchange (ETDEWEB)

      Dominguez, R.; Munekata, P.E.; Cittadini, A.; Lorenzo, J.M.

      2016-07-01

      The influence of three salting treatments (treatment II: 50% NaCl-50% KCl; III: 45% NaCl-25% KCl-20% CaCl2-10% MgCl2; IV: 30% NaCl-50% KCl-15% CaCl2-5% MgCl2) on the formation of volatile compounds throughout the process was studied and compared to those of a control “lacón” (treatment I: 100% NaCl). There was an intense formation of volatile compounds throughout the processing, particularly during the dry-ripening stage. The most abundant chemical family in all the formulations, in the final product was hydrocarbons followed by aldehydes. The total volatile compound release was more intense in the control “lacóns” (1164 AU×106 ·g–1dry matter) than in “lacóns” from formulations II, III and IV (817–891 AU×106 ·g−1dry matter). The “lacóns” from formulation I showed the highest amounts of aldehydes. The “lacóns” from formulations I and II presented the highest amounts of hydrocarbons. The main conclusion is that the replacement of NaCl produces changes in the volatile profile and could be affect the aroma of “lacón”. (Author)

    2. The effect of stochasticity on the lac operon: an evolutionary perspective.

      Directory of Open Access Journals (Sweden)

      Milan van Hoek

      2007-06-01

      Full Text Available The role of stochasticity on gene expression is widely discussed. Both potential advantages and disadvantages have been revealed. In some systems, noise in gene expression has been quantified, in among others the lac operon of Escherichia coli. Whether stochastic gene expression in this system is detrimental or beneficial for the cells is, however, still unclear. We are interested in the effects of stochasticity from an evolutionary point of view. We study this question in the lac operon, taking a computational approach: using a detailed, quantitative, spatial model, we evolve through a mutation-selection process the shape of the promoter function and therewith the effective amount of stochasticity. We find that noise values for lactose, the natural inducer, are much lower than for artificial, nonmetabolizable inducers, because these artificial inducers experience a stronger positive feedback. In the evolved promoter functions, noise due to stochasticity in gene expression, when induced by lactose, only plays a very minor role in short-term physiological adaptation, because other sources of population heterogeneity dominate. Finally, promoter functions evolved in the stochastic model evolve to higher repressed transcription rates than those evolved in a deterministic version of the model. This causes these promoter functions to experience less stochasticity in gene expression. We show that a high repression rate and hence high stochasticity increases the delay in lactose uptake in a variable environment. We conclude that the lac operon evolved such that the impact of stochastic gene expression is minor in its natural environment, but happens to respond with much stronger stochasticity when confronted with artificial inducers. In this particular system, we have shown that stochasticity is detrimental. Moreover, we demonstrate that in silico evolution in a quantitative model, by mutating the parameters of interest, is a promising way to unravel

    3. Regional meetings on energy 2008. Ile-de-France facing the energy stakes. Conference proceedings

      International Nuclear Information System (INIS)

      Lamy, Marie-Laure; Rocher, Philippe; Falque-Masset, Marie-Laure; Cazas, Judith; Labrousse, Muriel; Gorges, Pascale; Boulet, Sophie; Petit-Tesson, Christophe

      2009-01-01

      This document proposes a synthesis of the conference. It presents an assessment of the regional plan for energy management and development of local and renewable energies. The first part gives an overview of regional actions (in the Ile de France region) performed by the ADEME, or within the regional plan. The second part presents ROSE (a network for the statistical survey of energy and of greenhouse gas emissions in Ile de France) and its activity. Some remarkable actions are briefly presented: energy management by the city of Montreuil, energy management and sensitisation in a secondary school, a zero-energy building (a school in Limeil-Brevannes), geothermal energy in Orly, solar energy in social dwelling, and wood-heat network in Cergy-Pontoise

    4. “PESTEL Analizi” ile Türkiye-Almanya Ekonomik İlişkilerinin İncelenmesi

      OpenAIRE

      AKÇA, Hasan; ŞAHİN, Levent; KAYA, Zekayi

      2016-01-01

      Bu çalışmanın amacı; Türkiye ve Almanya arasındaki ekonomik ilişkileri PESTEL Analizi ile irdelemektir. Çalışmada ikincil veriler (1924-2015) kullanılmıştır. PESTEL Analizinden elde edilen bazı sonuçlar şu şekilde özetlenebilir. Almanya bir taraftan gelecekte enerji darboğazı çekmemek için enerji koridorunda bulunan Türkiye ile ilişkileri olumlu yönde tutmaya çalışırken; diğer yandan Türkiye’nin AB’ye üyeliğine mesafeli durmaktadır. 1954-2015/Ağustos döneminde Türkiye’ye yatırım yapan toplam ...

    5. X-ray emission from BL Lac objects: Comparison to the synchrotron self-Compton models

      International Nuclear Information System (INIS)

      Schwartz, D.A.; Madejski, G.; Ku, W.H.-M.

      1982-01-01

      As one part of our joint study of the X-ray properties of BL Lac objects, the authors compare the measured X-ray flux densities with those predicted using the synchrotron self-Compton (SSC) formalism (Jones et al. 1974). Naive application of the formalism predicts X-ray fluxes from 10 -3 to 10 5 those observed. They therefore ask what we can learn by simply assuming the SSC mechanism, and looking for ways to reconcile the observed and measured X-ray fluxes. This paper reports investigation of beaming factors due to relativistic ejection of a radiation source which is isotropic in its own rest frame. The authors conclude that large Lorentz factors, GAMMA approximately > 10, do not apply to BL Lac objects as a class. (Auth.)

    6. Carcass and meat traits of Morada Nova, Santa Ines and ½ Ile de France ½ Texel lambs finished in feedlot

      Directory of Open Access Journals (Sweden)

      Juliano Issakowicz

      2014-03-01

      Full Text Available The aim of this study was to evaluate the carcass and meat traits of Morada Nova, Santa Ines and ½ Ile de France ½ Texel lambs finished in feedlot. Weight and proportion of meatcuts, measures of carcass size and color, tenderness, cooking loss and ultimate pH of meat from 10 Morada Nova, 6 Santa Ines and 10 ½ Ile de France ½ Texel were evaluated. The lambs were finished in collective pens, fed ad libitum with 50% corn silage and 50% concentrate and slaughtered at about six months old. Analysis of variance was performed by the procedure PROC GLM of SAS (SAS Inst., Inc., Cary, NC and means were compared by Tukey test at 5% significance. The Morada Nova lambs had values of 14.1 kg, 13.9 kg, 0.240 kg/cm, 56.2 cm and 35.8 cm for hot and cold carcass weight, compactness index, hip and leg circumference respectively and these values were lower (P <0.05 to values observed in Santa Ines (19.4 kg, 18.8 kg, 0.283 cm/kg, 64.6 cm and 40.0 cm and in ½ Ile de France ½ Texel (18.6 kg, 18.2 kg, 0.305 cm/kg; 65.4 cm and 41.6 cm lambs. The hot and cold carcass yield did not differ (P> 0.05 among genetic groups. The scores for conformation and fat cover were higher (P <0.05 in ½ Ile de France ½ Texel lambs (2.4 and 3.0 and the carcass length was greater in Santa Ines lambs (66.3 cm. The ½ Ile de France ½ Texel lambs had smaller (P<0.05 proportion of neck and greater of leg (9.10% and 33.1% compared to Morada Nova lambs (10.3% and 30.4% and Santa Inês (10.9% and 31.6%. The weight of shoulder, leg, rack, ribs and flank was lower (P<0.05 in Morada Nova (1.306, 2.127 kg, 0.999 kg, 0.775 kg and 0.433 kg respectively compared to Santa Inês (1.820 kg, 2.972 kg, 1.355 kg, 0.959 and 0.509 kg and ½ Ile de France ½ Texel (1.791 kg, 3.007 kg, 1.212 kg, 1.016 kg and 0.563 kg. The neck was heavier in Santa Ines (1.038 kg which differed (P <0.05 from the other genetic groups (0.725 kg for Morada Nova and 0.830 kg for ½ Ile de France x ½ Texel lambs. The ½ Ile de

    7. A geological reconnaissance study of the Lac du Bonnet batholith

      International Nuclear Information System (INIS)

      Tammemagi, H.Y.; Kerford, P.S.; Requeima, J.C.; Temple, C.A.

      1980-02-01

      A geological reconnaissance survey was carried out of the Lac du Bonnet batholith, southeastern Manitoba, as part of the concept verification phase of the nuclear fuel waste disposal program for Canada. This report summarizes available geological information, presents the results of field mapping and discusses the geochemical analyses of rock samples. The geological and structural aspects of the batholith are described as well as its regional setting and possible genesis. (auth)

    8. Kinetic Analysis of Lactose Exchange in Proteoliposomes Reconstituted with Purified lac Permease

      NARCIS (Netherlands)

      Lolkema, Julius S.; Carrasco, Nancy; Kaback, H. Ronald

      1991-01-01

      Lactose exchange catalyzed by purified lac permease reconstituted into proteoliposomes was analyzed with unequal concentrations of lactose on either side of the membrane and at low pH so as to prevent equilibration of the two pools. Exchange with external concentrations below 1.0 mM is a

    9. Probing BL Lac and Cluster Evolution via a Wide-angle, Deep X-ray Selected Sample

      Science.gov (United States)

      Perlman, E.; Jones, L.; White, N.; Angelini, L.; Giommi, P.; McHardy, I.; Wegner, G.

      1994-12-01

      The WARPS survey (Wide-Angle ROSAT Pointed Survey) has been constructed from the archive of all public ROSAT PSPC observations, and is a subset of the WGACAT catalog. WARPS will include a complete sample of >= 100 BL Lacs at F_x >= 10(-13) erg s(-1) cm(-2) . A second selection technique will identify ~ 100 clusters at 0.15 = 0.304 +/- 0.062 for XBLs but = 0.60 +/- 0.05 for RBLs. Models of the X-ray luminosity function (XLF) are also poorly constrained. WARPS will allow us to compute an accurate XLF, decreasing the error bars above by over a factor of two. We will also test for low-luminosity BL Lacs, whose non-thermal nuclear sources are dim compared to the host galaxy. Browne and Marcha (1993) claim the EMSS missed most of these objects and is incomplete. If their predictions are correct, 20-40% of the BL Lacs we find will fall in this category, enabling us to probe the evolution and internal workings of BL Lacs at lower luminosities than ever before. By removing likely QSOs before optical spectroscopy, WARPS requires only modest amounts of telescope time. It will extend measurement of the cluster XLF both to higher redshifts (z>0.5) and lower luminosities (LX<1x10(44) erg s(-1) ) than previous measurements, confirming or rejecting the 3sigma detection of negative evolution found in the EMSS, and constraining Cold Dark Matter cosmologies. Faint NELGs are a recently discovered major contributor to the X-ray background. They are a mixture of Sy2s, starbursts and galaxies of unknown type. Detailed classification and evolution of their XLF will be determined for the first time.

    10. The SOS-LUX-LAC-FLUORO-Toxicity-test on the International Space Station (ISS).

      Science.gov (United States)

      Rabbow, E; Rettberg, P; Baumstark-Khan, C; Horneck, G

      2003-01-01

      In the 21st century, an increasing number of astronauts will visit the International Space Station (ISS) for prolonged times. Therefore it is of utmost importance to provide necessary basic knowledge concerning risks to their health and their ability to work on the station and during extravehicular activities (EVA) in free space. It is the aim of one experiment of the German project TRIPLE-LUX (to be flown on the ISS) to provide an estimation of health risk resulting from exposure of the astronauts to the radiation in space inside the station as well as during extravehicular activities on one hand, and of exposure of astronauts to unavoidable or as yet unknown ISS-environmental genotoxic substances on the other. The project will (i) provide increased knowledge of the biological action of space radiation and enzymatic repair of DNA damage, (ii) uncover cellular mechanisms of synergistic interaction of microgravity and space radiation and (iii) examine the space craft milieu with highly specific biosensors. For these investigations, the bacterial biosensor SOS-LUX-LAC-FLUORO-Toxicity-test will be used, combining the SOS-LUX-Test invented at DLR Germany (Patent) with the commercially available LAC-FLUORO-Test. The SOS-LUX-Test comprises genetically modified bacteria transformed with the pBR322-derived plasmid pPLS-1. This plasmid carries the promoterless lux operon of Photobacterium leiognathi as a reporter element under control of the DNA-damage dependent SOS promoter of ColD as sensor element. This system reacts to radiation and other agents that induce DNA damages with a dose dependent measurable emission of bioluminescence of the transformed bacteria. The analogous LAC-FLUORO-Test has been developed for the detection of cellular responses to cytotoxins. It is based on the constitutive expression of green fluorescent protein (GFP) mediated by the bacterial protein expression vector pGFPuv (Clontech, Palo Alto, USA). In response to cytotoxic agents, this system

    11. Altın Fiyatlarının Yapay Sinir Ağları ile Tahmini ve Bir Uygulama

      Directory of Open Access Journals (Sweden)

      Rıdvan YÜKSEL

      2016-03-01

      Full Text Available Bu çalışmada altın fiyatlarını yapay sinir ağları ile öngörmek amacıyla, altın fiyatlarını etkileyebileceği düşünülen değişkenler olan Gümüş fiyatları, Brent Petrol fiyatları, ABD doları/ EUR paritesi, EuroNext100 endeksi, Amerika Dow Jones Endeksi, 13 Hafta vadeli ABD bonosu faiz oranı ve ABD TÜFE endeksi kullanılarak modeller kurulmuştur. Yapay sinir ağları ile kurulan modellerden elde edilen tahmin sonuçları, gerçek değerler ile R2, RMSE, MAE ve MAPE (% gibi performans kriterleri hesaplanarak karşılaştırılmıştır. Elde edilen bulgular yapay sinir ağlarının altın fiyatlarının tahmininde başarı ile kullanılabileceğini göstermektedir. Yapılan duyarlılık analizinin sonuçları değerlendirildiğinde altın fiyatlarını etkileyen faktörlerin başında gümüş ve petrol fiyatlarının geldiği tespit edilmiştir.

    12. Antioxidant potentials of local fruits and foreign wines sold in Ile-Ife ...

      African Journals Online (AJOL)

      Some locally consumed fruits, sugarcane and wines sold in Ile-Ife, Nigeria, were investigated for their phenol content and antioxidant potential of the methanolic extracts with a view of exploring the healthpromoting effect of the fruits and wines. The total phenolic content in each fruit and wines was determined ...

    13. Efficacité des néonicotinoïdes et des pyréthrinoïdes utilisés contre le ...

      African Journals Online (AJOL)

      Efficacité des néonicotinoïdes et des pyréthrinoïdes utilisés contre le foreur des tiges du cacaoyer ( Eulophonotus myrmeleon Felder : Lepidoptera, Cossidae). Implications dans la stratégie de protection de la cacaoculture en Côte d'Ivoire.

    14. Bazı Bisküvi Çeşitlerinin Kimyasal Özellikleri ile Mineral ve Vitamin İçerikleri Üzerinde Araştırmalar

      Directory of Open Access Journals (Sweden)

      Hazım Özkaya

      2015-02-01

      Full Text Available Araştırmada üç firmaya ait 30 bisküvi örneğinin kimyasal bileşimleri ile mineral ve vitamin içerikleri araştırılmıştır. Bisküvi çeşitlerinin rutubet miktarları %2.1 ile %7.7 arasında değişmiş ve ortalama rutubet miktarı %4.3 olarak saptanmıştır. Kül miktarı %0.40 ile %1.54 arasında değişmiş, ortalama kül miktarı %0.74 olarak bulunmuştur. Protein miktarı çeşitler arasında %5.3 ile %10.4 arasında değişmiş ortalama protein miktarı %6.9 bulunmuştur. Örneklerin ham selüloz miktarları %0.14 ile %1.92 arasında olup ortalama ham selüloz miktarı %0.93’dür. Tuz miktarı bisküvi çeşitlerinde %0.18 ile %2.75 arasında değişmiş ortalama tuz miktarı %1.10 olarak bulunmuştur. Yağ miktarı %4.4 ile %30.5 arasında, ortalama %16.1 çıkmıştır. Örneklerin tiamin ve riboflavin miktarları sırası ile 0.35 mik. g/g ile 2.05 mik. g/g ve 0.35 mik. g/g ile 2.75 mik. g/g arasında değişmiş; ortalama tiamin ve riboflavin miktarları 0.92 mik. g/g ve 0.77 mik. g/g çıkmıştır. Ürünlerin makro ve mikro element miktarı, özellikle Fe ve Mn içerikleri normal bisküvilik una kıyasla daha yüksek bulunmuştur. Çeşitlerde saptanan mineral element miktarları birbiriyle korelasyon halinde çıkmamıştır.

    15. Ses veya Arayüz Yardımı ile Kontrol Edilebilen Mobil Robot Kol Tasarımı

      Directory of Open Access Journals (Sweden)

      Köksal GÜNDOĞDU

      2014-06-01

      Full Text Available Robot teknolojisinin hızlı gelişimine paralel olarak mobil araç, robot kol ve ses işleme teknolojisi de hızlı bir gelişim göstermiştir. Bu teknolojik gelişmede robotlardan beklenen en önemli parametrelerin başında güvenlik, çözüm üretme ve hız gelmektedir. Bu çalışmada, mobil araç üzerine bir robot kol yerleştirilmesi ve bu sitemlerin tasarlanan arayüz ve ses sistemi ile kontrol edilerek daha verimli ve hızlı çalışması amaçlanmıştır. Amaçlar doğrultusunda önce üzerinde bir robot kol bulunan bir mobil araç tasarımı gerçekleştirilmiş, sonrada bu mobil aracın ve robot kolun hem arayüz hem de ses komutları ile kontrol edilmesi sağlanmıştır. Yapılan test sonuçları incelendiğinde ses komutları ile kontrol sisteminin, arayüz ile kontrol sistemine göre daha verimli olduğu gözlenmiştir

    16. Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans

      DEFF Research Database (Denmark)

      Cheon, Seon Ah; Bal, Jyotiranjan; Song, Yunkyoung

      2012-01-01

      p) and Lac1p (CaLac1p) are functionally distinct. Lack of CaLag1p, but not CaLac1p, caused severe defects in the growth and hyphal morphogenesis of C. albicans. Deletion of CaLAG1 decreased expression of the hypha-specific HWP1 and ECE1 genes. Moreover, overexpression of CaLAG1 induced pseudohyphal...... growth in this organism under non-hypha-inducing conditions, suggesting that CaLag1p is necessary for relaying signals to induce hypha-specific gene expression. Analysis of ceramide and sphingolipid composition revealed that CaLag1p predominantly synthesizes ceramides with C24:0/C26:0 fatty acid moieties...

    17. Oral health status and treatment needs of elderly people in Ile-ife ...

      African Journals Online (AJOL)

      Background: Oral health is an important and often neglected component of an older person's general health and well- being. Objectives: To determine the oral health status of elderly persons in Ile-Ife, Nigeria. Methods: The oral health status of 95 elderly patients who presented at the General outpatient clinic of the Obafemi ...

    18. 1193-IJBCS-Article-Martin pepin Aina

      African Journals Online (AJOL)

      DR GATSING

      La protection des écosystèmes aquatiques est indispensable à l'équilibre écologique des espèces halieutiques et à une saine alimentation des populations locales. Le lac Nokoué situé au Sud du Bénin est sous l'influence de plusieurs formes de pollution qui résultent pour la plupart des activités anthropiques. Ce travail.

    19. Contribution a l'étude physicochimique de l'écosystème lacustre ...

      African Journals Online (AJOL)

      Contribution a l'étude physicochimique de l'écosystème lacustre Dayet Aoua au Maroc. ... Les analyses des formes azotées et des orthophosphates des eaux du lac donnent des valeurs très faibles, et ne décèlent aucune sorte de pollution de type organique pouvant engendrer son eutrophisation, ce qui permet de le ...

    20. Optical polarimetry of quasi-stellar and BL Lac objects

      International Nuclear Information System (INIS)

      Wills, D.; Wills, B.J.; Breger, M.; Hsu, J.

      1980-01-01

      We report observations of 39 extragalactic objects, using a new polarimeter at McDonald Observatory. Most of the observations were made in January and June 1980. Some new BL Lac objects were found, and some of the previously known members of this class were also observed. Polarization exceeding 3--4 times the formal rms uncertainties was found in about ten QSO's. Rapid changes of polarization and/or position angle occurred in some of the BL Lacertae objects, usually with <0.1-mag change in the total light

    1. Santé des adolescents et des jeunes au Burkina Faso : état des ...

      African Journals Online (AJOL)

      Il s'est agi d'une étude évaluative ayant utilisé une revue documentaire associée à une interview des acteurs clés et un atelier de validation et d'identification des interventions pertinentes pour un plan stratégique national. La situation de la santé des adolescents et des jeunes est caractérisée par des grossesses précoces ...

    2. La fabrique des sciences des institutions aux pratiques

      CERN Document Server

      Benninghoff, Martin; Crettaz von Roten, Fabienne; Merz, Martina

      2006-01-01

      Aujourd'hui, les façons de produire, d'organiser, d'évaluer et d'utiliser les savoirs sont en profond débat. De plus en plus, l'Etat, la société civile et l'économie tentent d'influencer les activités des universités et des laboratoires de recherche. Ces développements mettent à l'épreuve tout à la fois les fondements des systèmes d'enseignement supérieur et de recherche, l'autonomie des institutions scientifiques, la définition des frontières des savoirs et l'acceptation des sciences. Dans des contextes suisses et européens, cet ouvrage s'intéresse aux manières dont les sciences et les technologies sont fabriquées, en analysant leurs institutions et les pratiques. A partir d'une approche relationnelle, les sciences et les technologies sont conçues comme des phénomènes profondément sociaux, culturels et politiques. Une telle démarche déstabilise les visions parfois idéalisées et stéréotypées de la construction des savoirs. Des études de cas détaillées décrivent des phénomè...

    3. Coevolution of the Ile1,016 and Cys1,534 Mutations in the Voltage Gated Sodium Channel Gene of Aedes aegypti in Mexico.

      Directory of Open Access Journals (Sweden)

      Farah Z Vera-Maloof

      2015-12-01

      Full Text Available Worldwide the mosquito Aedes aegypti (L. is the principal urban vector of dengue viruses. Currently 2.5 billion people are at risk for infection and reduction of Ae. aegypti populations is the most effective means to reduce the risk of transmission. Pyrethroids are used extensively for adult mosquito control, especially during dengue outbreaks. Pyrethroids promote activation and prolong the activation of the voltage gated sodium channel protein (VGSC by interacting with two distinct pyrethroid receptor sites [1], formed by the interfaces of the transmembrane helix subunit 6 (S6 of domains II and III. Mutations of S6 in domains II and III synergize so that double mutants have higher pyrethroid resistance than mutants in either domain alone. Computer models predict an allosteric interaction between mutations in the two domains. In Ae. aegypti, a Ile1,016 mutation in the S6 of domain II was discovered in 2006 and found to be associated with pyrethroid resistance in field populations in Mexico. In 2010 a second mutation, Cys1,534 in the S6 of domain III was discovered and also found to be associated with pyrethroid resistance and correlated with the frequency of Ile1,016.A linkage disequilibrium analysis was performed on Ile1,016 and Cys1,534 in Ae. aegypti collected in Mexico from 2000-2012 to test for statistical associations between S6 in domains II and III in natural populations. We estimated the frequency of the four dilocus haplotypes in 1,016 and 1,534: Val1,016/Phe1,534 (susceptible, Val1,016/Cys1,534, Ile1,016/Phe1,534, and Ile1,016/Cys1,534 (resistant. The susceptible Val1,016/Phe1,534 haplotype went from near fixation to extinction and the resistant Ile1,016/Cys1,534 haplotype increased in all collections from a frequency close to zero to frequencies ranging from 0.5-0.9. The Val1,016/Cys1,534 haplotype increased in all collections until 2008 after which it began to decline as Ile1,016/Cys1,534 increased. However, the Ile1,016/Phe1

    4. Purified reconstituted lac carrier protein from Escherichia coli is fully functional.

      Science.gov (United States)

      Viitanen, P; Garcia, M L; Kaback, H R

      1984-03-01

      Proteoliposomes reconstituted with lac carrier protein purified from the plasma membrane of Escherichia coli catalyze each of the translocation reactions typical of the beta-galactoside transport system (i.e., active transport, counterflow, facilitated influx and efflux) with turnover numbers and apparent Km values comparable to those observed in right-side-out membrane vesicles. Furthermore, detailed kinetic studies show that the reconstituted system exhibits properties analogous to those observed in membrane vesicles. Imposition of a membrane potential (delta psi, interior negative) causes a marked decrease in apparent Km (by a factor of 7 to 10) with a smaller increase in Vmax (approximately equal to 3-fold). At submaximal values of delta psi, the reconstituted carrier exhibits biphasic kinetics, with one component manifesting the kinetic parameters of active transport and the other exhibiting the characteristics of facilitated diffusion. Finally, at low lactose concentrations, the initial velocity of influx varies linearly with the square of the proton electro-chemical gradient. The results provide quantitative support for the contention that a single polypeptide species, the product of the lac y gene, is responsible for each of the transport reactions typical of the beta-galactoside transport system.

    5. The extent of co-metabolism of glucose and galactose by L. lactis changes with the expression of the lacSZ operon from Streptococcus thermophilus

      DEFF Research Database (Denmark)

      Solem, Christian; Købmann, Brian Jensen; Jensen, Peter Ruhdal

      2008-01-01

      The lactose transporter and β-galactosidase from Streptococcus thermophilus, encoded by the lacSZ operon, were introduced into the lactose-negative strain Lactococcus lactis MG1363 and the expression of the lacSZ operon was modulated by substitution of the native promoter with randomized synthetic...... promoters. A series of strains with various expression levels of lacSZ were examined for their fermentation of lactose. Strains with a high expression level were found to metabolize lactose in a similar manner to S. thermophilus, i.e. the galactose moiety of lactose was excreted to the growth medium...... and only glucose was metabolized in glycolysis. Interestingly, strains with low expression of the operon showed a mixed acid metabolism and co-metabolism of galactose and glucose. The lactose flux increased gradually with increasing expression of the lacSZ operon until an optimum was observed...

    6. ABSORPSİYONLU SOGUTMA SİSTEMLERİ ile KLASiK SİSTEMLERİN KARŞILAŞTIRILMASI

      Directory of Open Access Journals (Sweden)

      MUSTAFA ÇELİK

      2003-04-01

      Full Text Available Bu çalışmada, doğalgaz ile çalışan absorpsiyonlu soğutma sistenıi ve klasik soğutma sisteminin karşıl aştırılması yapılmıştır. LiBr-H20 eriyiği kullanan bir ticari absorpsiyon makinasının sistem eleman larının termodinamik analizi yapılmıştır. Bu sistemde soğutma devresi eşa njörü ve eriyik devresi eşanjörlü sistem ile eş anjörsüz sistemlerin soğutma tesir katsayıları (STK ve ısıtma tesir katsayıları (ITK hesaplanarak, karşılaştırılması yapılmıştır. Bir vi Ila için LiBr-H20 eriyiği kulJaoan 23 KW'lık soğutma yüküne sahip absorpsiyon makinası ile klasik sisteme göre çalışa n soğutma makinasının ilk yatırım ve işletme giderlerine göre karşılaştırılmaları yapılmıştır

    7. Analyse géographique et modélisation des dynamiques d’urbanisation à La Réunion

      Directory of Open Access Journals (Sweden)

      Pascal Thinon

      2007-07-01

      Full Text Available Cet article propose un prototype de modèle d’interprétation des dynamiques urbaines sur l’Ile de la Réunion. En entrée, le modèle combine un ensemble de champs géographiques jouant en faveur ou en défaveur de l’urbanisation ; en sortie, il indique une propension à l’urbanisation de chaque lieu. Il est conçu de manière à permettre une analyse exploratoire de ces dynamiques selon une approche heuristique. Les premiers résultats ont permis d’obtenir, sur l’ensemble de l’île, une carte de la propension à l’urbanisation, jugée satisfaisante eu égard aux dynamiques observées entre 1989 et 2002 ; un premier scénario d’évolution, concernant les espaces de savanes à l’ouest de l’île, est également proposé. Les premiers travaux sur ce modèle, encore à un stade préliminaire, sont encourageants mais soulèvent de nombreuses questions concernant notamment le calibrage des facteurs et leur rôle respectif, l’intégration de nouveaux champs comme le voisinage, l’analyse des résidus, la mesure de la qualité du modèle ou bien encore la mobilisation de ce type de modèle comme outil d’accompagnement de projets de territoires.

    8. Dissemination in athymic nude mice of lacZ transfected small cell lung cancer cells identified by X-gal staining

      DEFF Research Database (Denmark)

      Rømer, M U; Christiansen, J; Brünner, N

      1995-01-01

      The small cell lung cancer cell lines GLC-2 and DMS 456 were genetically labeled with the lacZ gene and examined for invasive and metastatic potential in META/Bom nude mice. The lacZ gene encodes the enzyme beta-D- galactosidase, and cells expressing this enzyme were identified by staining...... with the chromogenic substrate X-gal. lacZ expressing cells were investigated after subcutaneous (s.c.) inoculation and intravenous (i.v.) injection. The X-gal detection of beta-D-galactosidase activity proved to be a rapid and easy means for specific and highly sensitive identification of metastases. All primary s.......c. tumors stained by X-gal. The primary tumors of GLC-2 regularly demonstrated local invasive growth and produced multiple metastases in several organs. In contrast, primary DMS 456 tumors only occasionally demonstrated local invasion and very rarely generated secondary foci. No experimental metastases were...

    9. Absorption in the spectra of quasi stellar objects and BL Lac objects

      International Nuclear Information System (INIS)

      Perry, J.J.; Burbidge, E.M.; Burbidge, G.R.

      1978-06-01

      An extensive review is given of the observations of absorption in the spectra of QSOs and BL Lac objects. In Table Ia we summarize all of the information available up to May 1, 1978 on objects which show absorption. Following discussion of the observations in Section II, possible interpretations are critically discussed. (orig.) [de

    10. Tunable Control of an Escherichia coli Expression System for the Overproduction of Membrane Proteins by Titrated Expression of a Mutant lac Repressor.

      Science.gov (United States)

      Kim, Seong Keun; Lee, Dae-Hee; Kim, Oh Cheol; Kim, Jihyun F; Yoon, Sung Ho

      2017-09-15

      Most inducible expression systems suffer from growth defects, leaky basal induction, and inhomogeneous expression levels within a host cell population. These difficulties are most prominent with the overproduction of membrane proteins that are toxic to host cells. Here, we developed an Escherichia coli inducible expression system for membrane protein production based on titrated expression of a mutant lac repressor (mLacI). Performance of the mLacI inducible system was evaluated in conjunction with commonly used lac operator-based expression vectors using a T7 or tac promoter. Remarkably, expression of a target gene can be titrated by the dose-dependent addition of l-rhamnose, and the expression levels were homogeneous in the cell population. The developed system was successfully applied to overexpress three membrane proteins that were otherwise difficult to produce in E. coli. This gene expression control system can be easily applied to a broad range of existing protein expression systems and should be useful in constructing genetic circuits that require precise output signals.

    11. 2287-IJBCS-Article-Seyni Sané

      African Journals Online (AJOL)

      hp

      interaction entre la resuspension et la sédimentation. Cette étude est consacrée à la détermination des processus responsables de la resuspension des particules dans le lac de Guiers situé au nord du Sénégal. Des échantillons ont été collectés au.

    12. Food-grade host/vector expression system for Lactobacillus casei based on complementation of plasmid-associated phospho-beta-galactosidase gene lacG.

      Science.gov (United States)

      Takala, T M; Saris, P E J; Tynkkynen, S S H

      2003-01-01

      A new food-grade host/vector system for Lactobacillus casei based on lactose selection was constructed. The wild-type non-starter host Lb. casei strain E utilizes lactose via a plasmid-encoded phosphotransferase system. For food-grade cloning, a stable lactose-deficient mutant was constructed by deleting a 141-bp fragment from the phospho-beta-galactosidase gene lacG via gene replacement. The deletion resulted in an inactive phospho-beta-galactosidase enzyme with an internal in-frame deletion of 47 amino acids. A complementation plasmid was constructed containing a replicon from Lactococcus lactis, the lacG gene from Lb. casei, and the constitutive promoter of pepR for lacG expression from Lb. rhamnosus. The expression of the lacG gene from the resulting food-grade plasmid pLEB600 restored the ability of the lactose-negative mutant strain to grow on lactose to the wild-type level. The vector pLEB600 was used for expression of the proline iminopeptidase gene pepI from Lb. helveticus in Lb. casei. The results show that the food-grade expression system reported in this paper can be used for expression of foreign genes in Lb. casei.

    13. Computing Optical Variable Periods of BL Lac Object S5 0716+714 ...

      Indian Academy of Sciences (India)

      2016-01-27

      Jan 27, 2016 ... From a large volume of literature, we have collected effective observation of BL Lac object S5 0716+714 in the optical band, and constructed its long-term light curve from 1994 to 2006 AD. The light curve shows that S5 0716+714 is very active and exhibits very complicated non-sinusoidal variations.

    14. Consolider la capacité locale d'adaptation aux changements ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Ces scénarios comprendront des estimations de l'évolution des précipitations, de l'évaporation et de l'apport d'eau en provenance du lac Titicaca, qui est le principal réservoir hydrique de l'Altiplano bolivien. Les chercheurs associeront ensuite ces scénarios à des modèles hydrologiques et des données prévisionnelles ...

    15. Les roches basiques et ultrabasiques des Lacs Robert et le Trias de Chamrousse (Massif de Belledonne) Etude petrologique et geologique

      NARCIS (Netherlands)

      Tex, den E.

      1950-01-01

      La région que j’ai étudiée et relevée est située dans les Alpes françaises, à environ 4° longitude est et 50°15’ latitude nord, et à environ 2000 mètres d’altitude. Elle fait partie de la chaîne dite „chaîne de Belledonne” qui s’étend des massifs de Beaufort et du Grand Mont dans le N N E jusqu’à

    16. Metabolism of fission products in man: Marshallese experience; Metabolisme des produits de fission radioactifs chez l'homme: donnees recueillies aux iles Marshall; Metabolizm radioaktivnykh produktov deleniya v organizme cheloveka. (dannye obsledovaniya zhite- lej marshal'skikh ostrovov); Metabolismo de productos de fision radiactivos en el hombre: datos obtenidos en los habitantes de las islas Marshall

      Energy Technology Data Exchange (ETDEWEB)

      Cohn, S. H. [Brookhaven National Laboratory, Upton, Long Island, NY (United States)

      1963-02-15

      The medical study of the Marshallese accidentally exposed to local fall-out in 1954 is unique in that; along with he Japanese fishermen study, it provides the only data existing on the metabolism of mixed fission products in a human population. Early diagnosis of the internal radioactive contamination was made by radiochemical analysis of the excreta of the exposed people and by radiochemical analysis of the tissues of animals simultaneously exposed. Initially, Sr{sup 89}, Ba{sup 140}, I{sup 131} and its shorter-lived daughters and a number of rare-earth elements contributed the major portion of the internal radiation dose. After a year, the principal radioisotopes were Sr{sup 90}, Cs{sup 137} and Zn{sup 65}. Subsequently these radionuclides and more recently, Co{sup 60}, have been measured periodically. Since 1958, the {gamma}-spectra of a number of Marshallese have been obtained with a portable whole-body counter. The report discusses the findings of these studies for the past eight years. The results of an early attempt o alter the rate of removal of the mixed fission products in the Marshallese with calcium disodium EDTA are presented. The metabolism of die radionuclides and their relationship to levels present in the environment is also discussed. (author) [French] L'enquete medicale a laquelle ont ete soumis les habitants des iles Marshall qui, en 1954, ont ete exposes accidentellement a des retombees locales presente un caractere unique en ce sens que, tout comme l'enquete sur les pecheurs japonais, elle fournit les seules donnees que l'on possede sur le metabolisme d'un melange de produits de fission chez l'homme. Un premier diagnostic de la contamination radioactive interne a ete fait par analyse radiochimique des excreta des sujets exposes et par analyse radiochimique des tissus des animaux exposes simultanement. Au debut, {sup 89}Sr, {sup 140}Ba, {sup 131}I et leurs produits de filiation de courte periode,ainsi qu'un certain nombre de terres rares

    17. Low-temperature heat capacity and thermodynamic properties of [Re2(Ile)4(H2O)8](ClO4)6 (Re=Nd, Er, Ile=isoleucine)

      International Nuclear Information System (INIS)

      Lan Xiaozheng; Tan Zhicheng; Liu Beiping; Nan Zhaodong; Sun Lixian; Xu Fen

      2003-01-01

      The heat capacities of two kinds of rare-earth element solid complexes with isoleucine [Re 2 (Ile) 4 (H 2 O) 8 ](ClO 4 ) 6 (where Re=Nd, Er, and Ile=isoleucine) have been measured by an automatic adiabatic calorimeter in the temperature range from 80 to 370 K. Two solid-solid phase transitions were found from the C p curve of Nd formed complex in the range of 165-175 K with a peak temperature of 167.88 K and in the range of 195-210 K with a peak temperature of 202.13 K. The corresponding molar enthalpies of these phase transitions were determined to be 404.61 J mol -1 and 2.955 kJ mol -1 , respectively. One solid-solid phase transition was found for the Er formed complex in the range of 190-205 K with a peak temperature of 193.42 K. The corresponding molar enthalpy of this transition was 14.11 kJ mol -1 . Smooth heat capacities and thermodynamic functions relative to the standard state (298.15 K), H T -H 298.15 , S T -S 298.15 and -[G T -G 298.15 ], of the two compounds, were calculated on basis of experimental heat capacity data. Possible mechanisms of thermal decompositions for the pair of compounds were suggested according to the thermogravimetric (TG) analysis

    18. Childhood intussusception in Ile-ife: What has changed?

      Directory of Open Access Journals (Sweden)

      Ademola Olusegun Talabi

      2013-01-01

      Full Text Available Background: Intussusception is one of the most common causes of intestinal obstruction in children. While the outcome has improved in the developed nations, the same cannot be said of the developing countries, more especially in the sub-Saharan region. This study aims to review our current experience in the management of childhood intussusception and factors affecting surgical outcome at the Obafemi Awolowo University Teaching Hospitals Complex Ile-Ife. Patients and Methods: This was a retrospective study of 78 patients treated for intussusception at paediatric surgical unit of Obafemi Awolowo University Teaching Hospitals Complex Ile-Ife between January 1993 and December 2011. The case notes of the patients were retrieved and the following information was recorded: Demographic characteristics, month of occurrence, clinical presentation, investigations, and management as well as the post-operative outcome. The patients were divided into two groups in terms of outcome. Results: There were 58 males and 20 females (M:F = 2.9-1. The age of most of the patients was between 3 months and 9 months with peak incidence at 6 months. Most patients 46 (58.9% were seen during the dry season of December to April. Only six patients (7.7% presented within 24 hours of onset of illness. More than half of the patients presented after 24 hours. Passage of red currant stool, vomiting, abdominal pain, fever, and abdominal distension, passage of watery stool, anal protrusion and palpable abdominal mass in various combinations were the clinical features. All the patients had surgical operations. The most common type of intussusception was ileo-colic type in 64 patients (82.1%. Intestinal resection rate was 41%. The overall mortality rate was 15.4%. Conclusion: There was a delay in presentation of children with intussusception with high post-operative mortality.

    19. Tombes et cimetières éthiopiens : des rois, des saints, des anonymes1

      OpenAIRE

      Derat, Marie-Laure

      2009-01-01

      L’histoire des tombes et cimetières éthiopiens, dans la longue durée, en est encore à ses balbutiements. Si les tombes des saints et des rois nous sont un peu mieux connus grâce à des textes témoignant à la fois des enjeux entourant les sépultures de ces personnages hors du commun et des soins apportés à leur inhumation, en revanche, les cimetières ordinaires échappent encore largement à l’enquête, en grande partie parce que le commun des mortels est inhumé dans l’anonymat et dans un grand dé...

    20. Évaluation des pratiques agricoles des légumes feuilles : le cas des ...

      African Journals Online (AJOL)

      Face à ce constat, le défi de la recherche serait la détermination du niveau actuel de contamination des légumes feuilles et des eaux du barrage et celui de l'État serait l'initiation de programmes de sensibilisation des producteurs par rapport à une gestion plus rigoureuse des pesticides. Mots-clés : pratiques paysannes, ...

    1. La convergence des rôles respectifs des relationnistes et des journalistes influence-t-elle la perception qu'ils ont les uns des autres?

      DEFF Research Database (Denmark)

      Valentini, Chiara

      2017-01-01

      la convergence des rôles respectifs des praticiens des relations publiques et des journalistes a un effet favorable sur la perception qu’ils ont les uns des autres. L’effet est plus marqué chez les praticiens des relations publiques, car leur vision de la profession en journalisme correspond à celle...

    2. Mécanique des sols et des roches

      CERN Document Server

      Vullier, Laurent; Zhao, Jian

      2016-01-01

      La mécanique des sols et la mécanique des roches sont des disciplines généralement traitées séparément dans la littérature. Pour la première fois, un traité réunit ces deux spécialités, en intégrant également les connaissances en lien avec les écoulements souterrains et les transferts thermiques. A la fois théorique et pratique, cet ouvrage propose tout d'abord une description détaillée de la nature et de la composition des sols et des roches, puis s'attache à la modélisation de problèmes aux conditions limites et présente les essais permettant de caractériser les sols et les roches, tant d'un point de vue mécanique qu'hydraulique et thermique. La problématique des sols non saturés et des écoulements multiphasiques est également abordée. Une attention particulière est portée aux lois de comportement mécanique et à la détermination de leurs paramètres par des essais in situ et en laboratoire, et l'ouvrage offre également une présentation détaillée des systèmes de classi...

    3. African Journal of Science and Technology (AJST) MACROPHYTES ...

      African Journals Online (AJOL)

      opiyo

      incidence des macrophytes aquatiques et du plancton sur la qualité des eaux du lac de Guiers», financé par la région Wallonne de Belgique avec l'appui de la. Fondation Universitaire Luxembourgeoise (Arlon). Nous les remercions pour leur concours.

    4. Copépodes, Cladocères et Rotifères du lac Sidi M'hamed Benali (Algérie Nord-Occidentale

      Directory of Open Access Journals (Sweden)

      Mohamed Ali Bouzidi

      2010-03-01

      Full Text Available En 2008, 33 espèces de Cladocères, Copépodes et Rotifères ont été observées dans le lac Sidi M'hamed Benali (contre 12 seulement en 1992.Les Copépodes dominent en mars, avril, juillet, août et septembre, avec respectivement des dominances (Do égales à : 56,6 %, 55,0 %, 55,0 %, 46,4 % et 90,0 %. Les Cladocères dominent en février (Do = 37,2 %, mai (Do = 47,4 % et décembre (Do = 48,6 %. Les Rotifères sont extrêmement abondants et présentent une large dominance en janvier (Do = 95,3 %. La population zooplanctonique est très faible en juillet et en août. Au cours de l'année le peuplement varie en fonction de la température, des conditions hydrologiques, de l'abondance de la nourriture et de la prédation par les poissons.In 2008, 33 species of Cladocers, Copepods and Rotifers have been observed in Sidi M’hamed Benali Lake (against only 12 species in 1992. The Copepods dominate in March, April, July, August and September, respectively with dominance (Do equal to 56.6 %, 55.0 %, 55.0 %, 46.4 % and 90.0 %. Cladocers dominated in February (Do = 37.2 %, May (Do = 47.4 % and December (Do = 48.6 %. The rotifers are extremely abundant and have a wide dominance in January (Do = 95.3%. The zooplankton population is very low in July and August. During the year, the population varies with temperature, water conditions, abundance of food and predation by fishes.

    5. Parental Socio-Economic Status as Correlate of Child Labour in Ile-Ife, Nigeria

      Science.gov (United States)

      Elegbeleye, O. S.; Olasupo, M. O.

      2012-01-01

      This study investigated the relationship between parental socio-economic status and child labour practices in Ile-Ife, Nigeria. The study employed survey method to gather data from 200 parents which constituted the study population. Pearson Product Moment Correlation and t-test statistics were used for the data analyses. The outcome of the study…

    6. Using the Markov chain Monte Carlo method to study the physical properties of GeV-TeV BL Lac objects

      Science.gov (United States)

      Qin, Longhua; Wang, Jiancheng; Yang, Chuyuan; Yuan, Zunli; Mao, Jirong; Kang, Shiju

      2018-01-01

      We fit the spectral energy distributions (SEDs) of 46 GeV-TeV BL Lac objects in the frame of leptonic one-zone synchrotron self-Compton (SSC) model and investigate the physical properties of these objects. We use the Markov chain Monte Carlo (MCMC) method to obtain the basic parameters, such as magnetic field (B), the break energy of the relativistic electron distribution (γ ^' }b), and the electron energy spectral index. Based on the modeling results, we support the following scenarios for GeV-TeV BL Lac objects. (1) Some sources have large Doppler factors, implying other radiation mechanism should be considered. (2) Compared with flat spectrum quasars (FSRQs), GeV-TeV BL Lac objects have weaker magnetic fields and larger Doppler factors, which cause the ineffective cooling and shift the SEDs to higher bands. Their jet powers are around 4.0 × 1045 erg s-1, compared with radiation power, 5.0 × 1042 erg s-1, indicating that only a small fraction of jet power is transformed into the emission power. (3) For some BL Lacs with large Doppler factors, their jet components could have two substructures, e.g., the fast core and the slow sheath. For most GeV-TeV BL Lacs, Kelvin-Helmholtz instabilities are suppressed by their higher magnetic fields, leading to micro-variability or intro-day variability in the optical bands. (4) Combined with a sample of FSRQs, an anti-correlation between the peak luminosity, Lpk, and the peak frequency, νpk, is obtained, favoring the blazar sequence scenario. In addition, an anti-correlation between the jet power, Pjet, and the break Lorentz factor, γb, also supports the blazar sequence.

    7. Sebze Püresi ile Üretilen Yoğurtların Tekstürel ve Duyusal Özelliklerinin Belirlenmesi

      Directory of Open Access Journals (Sweden)

      Tülay Özcan

      2016-07-01

      Full Text Available Bu çalışmada kontrol (K; balkabağı (YBK, havuç (YHA, bezelye (YBE ve yeşil kabak püreli (YYK yoğurt olmak üzere 5 farklı set tipi yoğurt üretilmiştir. Sebzeli yoğurtlarda bulunan diyet liflerinin bakteri gelişmesini teşvik eden potansiyel etkisi sonucu Streptococcus thermophilus ile Lactobacillus delbrueckii subsp. bulgaricus sayılarının arttığı saptanmıştır. Yoğurtların sebze püreleri ile zenginleştirilmesinin pH, titrasyon asitliği, serum ayrılması, duyusal özelikler ile sertlik, iç yapışkanlık, konsistens ve viskozite indeksi gibi tekstürel özellikler üzerinde etkili olduğu gözlenmiştir. Havuç püresi ile üretilen yoğurtlarda viskozite, konsistens ve sertliğin yüksek olduğu saptanırken, yeşil kabak ilaveli olanlar daha zayıf tekstürel özellikler göstermiştir. Sonuç olarak sebze püresi ilavesinin set tipi yoğurtlarda tekstürel özelliklerinin iyileştirilmesi konusunda önemli rol oynadığı ve fonksiyonel süt ürünlerinin geliştirilmesinde kullanılabileceği belirlenmiştir.

    8. Évaluation des pratiques agricoles des légumes feuilles : le cas des ...

      African Journals Online (AJOL)

      SARAH

      30 sept. 2017 ... ... de Biochimie et Immunologie Appliquée, Centre de Recherche en Sciences Biologiques, Alimentaires et .... l'intoxication des agriculteurs et des consommateurs, ... source d'alimentation en eau et au pouvoir d'achat des.

    9. Discovery of Intermediates of lacZ β-Galactosidase Catalyzed Hydrolysis Using dDNP NMR

      DEFF Research Database (Denmark)

      Kjeldsen, Christian; Ardenkjær-Larsen, Jan Henrik; Duus, Jens Ø.

      2018-01-01

      Using dissolution dynamic nuclear polarization, the sensitivity of single scan solution state 13C NMR can be improved up to 4 orders of magnitude. In this study, the enzyme lacZ β-galactosidase from Escherichia coli was subjected to hyperpolarized substrate, and previously unknown reaction...

    10. Discovery of Intermediates of lacZ beta-Galactosidase Catalyzed Hydrolysis Using dDNP NMR

      DEFF Research Database (Denmark)

      Kjeldsen, Christian; Ardenkjær-Larsen, Jan Henrik; Duus, Jens Øllgaard

      2018-01-01

      Using dissolution dynamic nuclear polarization, the sensitivity of single scan solution state C-13 NMR can be improved up to 4 orders of magnitude. In this study, the enzyme lacZ beta-galactosidase from Escherichia coli was subjected to hyperpolarized substrate, and previously unknown reaction...

    11. Modelisation des effets physico-techniques pour la conception des ...

      African Journals Online (AJOL)

      automatisation dans les installations industrielles a besoin d'une régulation automatique des commandes des processus technologiques pour lesquelles certaines contraintes sont à relever compte tenu des exigences des innovations scientifiques de ...

    12. lacZ transduced human breast cancer xenografts as an in vivo model for the study of invasion and metastasis

      DEFF Research Database (Denmark)

      Brünner, N; Thompson, E W; Spang-Thomsen, M

      1992-01-01

      in the animals by usual histological procedures would require extensive sectioning of the whole animal. To overcome this problem, we transduced human breast cancer cells with a replication-defective Moloney murine leukaemia retroviral vector (M-MuLV) containing both neoR (neomycin resistance) and lacZ genes...... but not the surrounding mouse tissue on either whole tissue blocks or histological sections. The staining procedure was highly sensitive, allowing detection of microfoci of human cancer cells, and quantitative estimation of the metastatic capacity of the cells. These results indicate that lacZ transduction of human...

    13. La élite parlamentaria de Canarias: perfil sociodemográfico

      Directory of Open Access Journals (Sweden)

      Javier Sánchez Herrera

      2004-11-01

      Full Text Available En général, les recherches contemporaines sur les élites soulignent l'existence d'une série de données basiques qui leur sont propres : genre masculin, origines sociales établies, formation supérieure, centres éducatifs de qualité, âge mûre, résidences dans des quartiers aristocratiques, professions typiques (juristes, professeurs, bureaucrates, cadre supérieur, etc.. Dans ce travail, après la présentation de l'histoire sociopolitique des iles Canaries, qui refléte une préoccupation sur le plan de l'égalité des opportunités, nous étudions les participants de cette élite parlementaire dans les iles, sur le plan des catégories suivantes : classe sociale, âge, genre, origine régionale, mobilité sociale, niveau d'études, profession et lieu de domicile.

    14. Kliimateadlastele ja Al Gore'ile läinud Nobel oli oodatud otsus / Liisi Poll, Oliver Tiks

      Index Scriptorium Estoniae

      Poll, Liisi, 1980-

      2007-01-01

      Nobeli preemiat välja andev komitee Oslos otsustas anda Nobeli rahupreemia rahvusvahelisele kliimamuutuste töörühmale ja USA endisele asepresidendile Al Gore'ile. Lisa: Tänavune Nobeli rahupreemia

    15. Vecteurs Singuliers des Theories des Champs Conformes Minimales

      Science.gov (United States)

      Benoit, Louis

      En 1984 Belavin, Polyakov et Zamolodchikov revolutionnent la theorie des champs en explicitant une nouvelle gamme de theories, les theories quantiques des champs bidimensionnelles invariantes sous les transformations conformes. L'algebre des transformations conformes de l'espace-temps presente une caracteristique remarquable: en deux dimensions elle possede un nombre infini de generateurs. Cette propriete impose de telles conditions aux fonctions de correlations qu'il est possible de les evaluer sans aucune approximation. Les champs des theories conformes appartiennent a des representations de plus haut poids de l'algebre de Virasoro, une extension centrale de l'algebre conforme du plan. Ces representations sont etiquetees par h, le poids conforme de leur vecteur de plus haut poids, et par la charge centrale c, le facteur de l'extension centrale, commune a toutes les representations d'une meme theorie. Les theories conformes minimales sont constituees d'un nombre fini de representations. Parmi celles-ci se trouvent des theories unitaires dont les representation forment la serie discrete de l'algebre de Virasoro; leur poids h a la forme h_{p,q}(m)=[ (p(m+1) -qm)^2-1] (4m(m+1)), ou p,q et m sont des entiers positifs et p+q= 2. Ces representations possedent un sous-espace invariant engendre par deux sous-representations avec h_1=h_{p,q} + pq et h_2=h_{p,q} + (m-p)(m+1-q) dont chacun des vecteurs de plus haut poids portent le nom de vecteur singulier et sont notes respectivement |Psi _{p,q}> et |Psi_{m-p,m+1-q}>. . Les theories super-conformes sont une version super-symetrique des theories conformes. Leurs champs appartiennent a des representation de plus haut poids de l'algebre de Neveu-Schwarz, une des deux extensions super -symetriques de l'algebre de Virasoro. Les theories super -conformes minimales possedent la meme structure que les theories conformes minimales. Les representations sont elements de la serie h_{p,q}= [ (p(m+2)-qm)^2-4] /(8m(m+2)) ou p,q et m sont

    16. Un outil pour la valorisation des laitiers d’aciérie de conversion en techniques routières A tool for BOF Slag’s valorisation in roads

      Directory of Open Access Journals (Sweden)

      Dao P-L.

      2012-09-01

      Full Text Available Les laitiers d’aciérie de conversion (LAC sont les résidus de la transformation de la fonte en acier. Ces produits abondants (plus de 2 millions de tonnes/an en France sont peu valorisés en génie civil car ils contiennent de la chaux libre qui, en s’hydratant, cause des expansions souvent conséquentes. Un outil pour leur utilisation dans les mélanges granulaires routiers a été développé. Il est basé sur deux modèles paramétriques décrivant, l’un le taux de grains dégradés en milieu aqueux à température et à âge donnés en fonction de la teneur en chaux libre, de la taille et de la structure des grains, l’autre l’expansion volumique d’empilements granulaires, purs ou mélangés à des granulats inertes, soumis à un flux de vapeur. La combinaison de ces deux modèles avec le Modèle d’Empilement Compressible du LCPC permet alors de prédire la cinétique de l’expansion d’un mélange granulaire quelconque, et de désigner des mélanges optimisés en termes de granularité et de proportions, incorporant des LAC, pour un usage spécifié par une expansion tolérée à une échéance et dans un environnement donnés. BOF Slags are residues of the transformation of melting steel. These abundant products (more than 2 million tonnes per year in France are little valued in civil engineering because they contain free lime which, by hydrating, cause often substantial expansions. A tool for use in road granular mixtures has been developed. It is based on two parametric models describing; i the rate of grain degraded in water at temperature and age given, in function of the content of free lime, the size and the structure of the grain, ii the expansion of the packing granular, pure or mixed with inert aggregates, exposed to a flow of steam. The combination of these two models with the Compressible Packing Model of LCPC allows then the prediction of the kinetics of expansion of a granular mixture, and the designation of

    17. The genus Hypostomus Lacépède, 1803, and its Surinam representatives (Siluriformes, Loricariidae)

      NARCIS (Netherlands)

      Boeseman, M.

      1968-01-01

      CONTENTS Introduction................... 3 The generic name................. 4 The type species of Hypostomus Lacépède.......... 6 The identity of Acipenser plecostomus Linnaeus........ 9 The distribution and habitats of the Surinam species........ 12 The relationship of the Surinam

    18. 2635 IJBCS-Article-Dr JosephineYameogo

      African Journals Online (AJOL)

      hp

      La dégradation du lac Bam au Burkina Faso préoccupe les acteurs nationaux et internationaux. Le présent travail vise principalement à contribuer à la connaissance des facteurs de dégradation et des stratégies de gestion durable. Spécifiquement, il voudrait identifier les acteurs impliqués dans la gestion des berges ;.

    19. Utilisation sans risque des eaux usées, des excréta et des eaux ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Les responsables de ce projet piloteront l'application et l'adaptation des principes directeurs relatifs à l'utilisation sans risque des eaux usées, des excreta et des eaux grises en agriculture et en aquaculture (Guidelines for the Safe Use of Wastewater, Excreta and Greywater in Agriculture and Aquaculture), que ...

    20. ANALYSE DES PERCEPTIONS LOCALES ET DES FACTEURS ...

      African Journals Online (AJOL)

      AISA

      1Faculté des Sciences Agronomiques (FSA), Université d'Abomey-Calavi (UAC), 01 BP 526 Cotonou Bénin. Email : cgbemavo@yahoo.fr. 2Institut National des Recherches Agricoles du Bénin, Centre de Recherches Agricoles d'Agonkanmey (CRA-A),. Laboratoire des Sciences du Sol, Eau et Environnement (LSSEE).

    1. variabilite des productions et des revenus des exploitations

      African Journals Online (AJOL)

      3Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), UMR Innovation,. Montpellier, France. Doubangolo COULIBALY, Email kone_b@yahoo.fr. RESUME. La durabilité des systèmes de production à base de coton dans un contexte de variabilité des prix aux producteurs et de ...

    2. Le statut vitaminique des individus et des populations…

      Directory of Open Access Journals (Sweden)

      Icart Jean-Claude

      2000-05-01

      Full Text Available Comme le souligne un récent rapport du Haut comité de santé publique, le statut vitaminique des individus et des populations demeure une question d’actualité. Si les études ne révèlent plus de signes évocateurs de carence, au plus des problèmes de déficiences pour certains groupes à risque, des interrogations, demeurent malgré le contexte d’abondance, concernant la couverture des besoins, laquelle pourrait s’avérer inférieure aux valeurs considérées comme satisfaisantes.

    3. Application des TIC à l'atténuation des effets des catastrophes dans ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      L'Amérique centrale est souvent aux prises avec des inondations et des ... (SIG) et de traitement des images, afin de cartographier les dangers et de modéliser les ... de l'Institut d'étude du développement international de l'Université McGill.

    4. 146 Apport de la télédétection à la cartographie de l'évolution spatio ...

      African Journals Online (AJOL)

      SORO GBOMBELE

      Les précisions globales obtenues pour les images classifiées sont de 88,47% ... comportement hydrologique des bassins soudano-sahéliens paraît de fait en pleine ... d'un changement climatique, l'évolution des couverts végétaux, des états de surface ... l'étude de l'occupation du sol dans la région des Lacs a été réalisée.

    5. A case-control study of the HER2 Ile655Val polymorphism in relation to risk of invasive breast cancer

      International Nuclear Information System (INIS)

      Nelson, Stephanie E; Gould, Michael N; Hampton, John M; Trentham-Dietz, Amy

      2005-01-01

      Overexpression of the HER2 proto-oncogene in human cancer cells has been associated with a poor prognosis, and survival improves with therapy targeting the HER2 gene. Animal studies and protein modeling suggest that the Ile655Val polymorphism located in the transmembrane domain of the HER2 protein might influence breast cancer development by altering the efficiency of homodimerization. To investigate this genetic polymorphism, incident cases of invasive breast cancer (N = 1,094) and population controls of a similar age (N = 976) were interviewed during 2001 to 2003 regarding their risk factors for breast cancer. By using DNA collected from buccal samples mailed by the participants, the HER2 Ile655Val polymorphism was evaluated with the Applied Biosystems allelic discrimination assay. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were estimated by logistic regression adjusted for numerous breast cancer risk factors. Analysis was restricted to women with self-reported European descent. Prevalence of the Val/Val genotype was 5.6% in cases and 7.1% in controls. In comparison with the Ile/Ile genotype, the Ile/Val genotype was not significantly associated with breast cancer risk (OR 0.97, 95% CI 0.79 to 1.18), whereas the Val/Val genotype was associated with a reduced risk (OR 0.63, 95% CI 0.42 to 0.92). This inverse association seemed strongest in older women (OR 0.51, 95% CI 0.29 to 0.89 for women aged more than 55 years), women without a family history of breast cancer (OR 0.54, 95% CI 0.35 to 0.84), postmenopausal women with greater body mass index (OR 0.43, 95% CI 0.20 to 0.91 for a body mass index of 25.3 kg/m 2 or more), and cases diagnosed with non-localized breast cancer (OR 0.49, 95% CI 0.26 to 0.90). Although results from our population-based case-control study show an inverse association between the HER2 Ile655Val polymorphism and risk of invasive breast cancer, most other studies of this single-nucleotide polymorphism suggest an overall null

    6. Low-level jets as monitored by a tri-axial acoustic sounder in Ile-Ife ...

      African Journals Online (AJOL)

      level jets in the atmospheric boundary layer at Ile-Ife (7.5N, 4.5E), Nigeria. From about 400 sets of wind data processed for the period: June - September 1991, low-level jets of speeds ranging between 6.0ms-1 and 12.50 ms-1, were observed ...

    7. La gestion des résultats des entreprises innovantes

      OpenAIRE

      Dumas, Guillaume

      2014-01-01

      Cette thèse s’intéresse à la gestion des résultats dans le cadre des entreprises innovantes. Elle est constituée de trois articles. Dans le premier, il s’agit d’examiner si les résultats des entreprises innovantes sont gérés et si le stade de développement des innovations influence cette gestion des résultats. Il apparaît que les résultats des entreprises innovantes sont gérés à la hausse. Cette gestion ne semble intervenir qu’au cours de l’activité d’innovation (c’est-à-dire lorsque les entr...

    8. Etude des erreurs d'estimation des populations par la méthode des captures successives (DeLURY, 2 captures et des captures-recaptures (PETERSEN

      Directory of Open Access Journals (Sweden)

      LAURENT M.

      1978-01-01

      Full Text Available L'estimation des populations naturelles par capture-recapture et par captures successives est souvent entachée d'erreur car, dans de nombreux cas, l'hypothèse fondamentale d'égalité des probabilités de captures pour tous les individus dans le temps et dans l'espace n'est pas respectée. Dans le cas des populations de poissons envisagés ici, les captures ont lieu par la pêche électrique. On a pu chiffrer l'ordre de grandeur des erreurs systématiques faites sur l'estimation des peuplements, en fonction des conditions particulières, biotiques et abiotiques, des différents milieux inventoriés.

    9. Observations of low and intermediate-frequency-peaked BL Lacs above 100 GeV with VERITAS

      Directory of Open Access Journals (Sweden)

      Errando M.

      2013-12-01

      Full Text Available Most of the ~ 50 blazars detected to date at TeV energies (E > 0.1 TeV are high-frequency-peaked BL Lacs (HBLs. Only a handful episodic detections of low- and intermediate-frequency-peaked BL Lacs (LBL/IBLs, with synchrotron peak frequencies in the infrared and optical regime have been reported by ground-based gamma-ray telescopes, typically during high-flux states. The VERITAS array located in southern Arizona has observed five known TeV LBL/IBLs since 2009: 3C 66A, WComae, PKS 1424+240, S5 0716+714 and BL Lacertae, with exposures of 5-10 hours/year, which so far resulted in the detection of a bright, sub-hour timescale gamma-ray flare of BL Lacertae in June 2011. We also report the detection and characterization of two new IBLs: VER J0521+211 and B2 1215+30.

    10. Dynamical Black Hole Masses of BL Lac Objects from the Sloan Digital Sky Survey

      NARCIS (Netherlands)

      Plotkin, Richard M.; Markoff, Sera; Trager, Scott C.; Anderson, Scott F.

      2012-01-01

      We measure black hole masses for 71 BL Lac objects from the Sloan Digital Sky Survey (SDSS) with redshifts out to z ∼ 0.4. We perform spectral decompositions of their nuclei from their host galaxies and measure their stellar velocity dispersions. Black hole masses are then derived from the black

    11. The LAC Test: A New Look at Auditory Conceptualization and Literacy Development K-12.

      Science.gov (United States)

      Lindamood, Charles; And Others

      The Lindamood Auditory Conceptualization (LAC) Test was constructed with the recognition that the process of decoding involves an integration of the auditory, visual, and motor senses. Requiring the manipulation of colored blocks to indicate conceptualization of test patterns spoken by the examiner, subtest 1 entails coding of identity, number,…

    12. Effect of the partial NaCl substitution by other chloride salts on the volatile profile during the ripening of dry-cured lacón

      Directory of Open Access Journals (Sweden)

      Domínguez, R.

      2016-06-01

      Full Text Available The influence of three salting treatments (treatment II: 50% NaCl-50% KCl; III: 45% NaCl-25% KCl-20% CaCl2-10% MgCl2; IV: 30% NaCl-50% KCl-15% CaCl2-5% MgCl2 on the formation of volatile compounds throughout the process was studied and compared to those of a control “lacón” (treatment I: 100% NaCl. There was an intense formation of volatile compounds throughout the processing, particularly during the dry-ripening stage. The most abundant chemical family in all the formulations, in the final product was hydrocarbons followed by aldehydes. The total volatile compound release was more intense in the control “lacóns” (1164 AU_106·g-1dry matter than in “lacóns” from formulations II, III and IV (817-891 AUx106·g-1dry matter. The “lacóns” from formulation I showed the highest amounts of aldehydes. The “lacóns” from formulations I and II presented the highest amounts of hydrocarbons. The main conclusion is that the replacement of NaCl produces changes in the volatile profile and could be affect the aroma of “lacón”.Se estudió la influencia de tres tratamientos de salado (tratamiento II: 50 % NaCl-50 % KCl; III: 45 % NaCl-25 % KCl-20 % CaCl2-10 % MgCl2; IV: 30 % NaCl-50 % KCl-15 % CaCl2-5 % MgCl2 en la formación de compuestos volátiles durante la elaboración de lacón, en comparación con un control (tratamiento I: 100 % NaCl. Hubo una intensa formación de compuestos volátiles durante el procesado, principalmente durante la fase de secado-maduración. La familia química más abundante en el producto final fueron los hidrocarbonos, seguidos por los aldehídos. La liberación de volátiles fue más intensa en los lacones control (1164 AU_106·g-1 materia seca que en los otros lacones (817-891 AUx106· g-1 materia seca. Los lacones de la formulación I mostraron las mayores cantidades de aldehídos, y los lacones de las formulaciones I y II presentaron los mayores contenidos de hidrocarburos. La principal conclusi

    13. Injectabilite des coulis de ciment dans des milieux fissures

      Science.gov (United States)

      Mnif, Thameur

      Le travail presente ici est un bilan du travaux de recherche effectues sur l'injectabilite des coulis de ciment dans lu milieux fissures. Un certain nombre de coulis a base de ciment Portland et microfin ont ete selectionnes afin de caracteriser leur capacite a penetrer des milieux fissures. Une partie des essais a ete menee en laboratoire. L'etude rheologique des differents melanges a permis de tester l'influence de l'ajout de superplastifiant et/ou de fumee de silice sur la distribution granulometrique des coulis et par consequent sur leur capacite a injecter des colonnes de sable simulant un milieu fissure donne. La classe granulometrique d'un coulis, sa stabilite et sa fluidite sont apparus comme les trois facteurs principaux pour la reussite d'une injection. Un facteur de finesse a ete defini au cours de cette etude: base sur la classe granulometrique du ciment et sa stabilite, il peut entrer dans la formulation theorique du debit d'injection avant application sur chantier. La deuxieme et derniere partie de l'etude presente les resultats de deux projets de recherche sur l'injection realises sur chantier. L'injection de dalles de beton fissurees a permis le suivi de l'evolution des pressions avec la distance au point d'injection. L'injection de murs de maconnerie a caractere historique a montre l'importance de la definition de criteres de performance des coulis a utiliser pour traiter un milieu donne et pour un objectif donne. Plusieurs melanges peuvent ainsi etre predefinis et mis a disposition sur le chantier. La complementarite des ciments traditionnels et des ciments microfins devient alors un atout important. Le choix d'utilisation de ces melanges est fonction du terrain rencontre. En conclusion, cette recherche etablit une methodologie pour la selection des coulis a base de ciment et des pressions d'injection en fonction de l'ouverture des fissures ou joints de construction.

    14. Organochlorine pesticide residues in dried cocoa beans obtained from cocoa stores at Ondo and Ile-Ife, Southwestern Nigeria

      Directory of Open Access Journals (Sweden)

      J.A.O. Oyekunle

      Full Text Available Levels of organochlorine pesticides (OCPs were determined in dried cocoa beans obtained from cocoa produce stores at Ondo and Ile-Ife, Southwestern Nigeria. Cocoa beans samples were sun dried to a constant weight, pulverized and soxhlet extracted with dichloromethane to obtain the OCPs. Qualitative identification and quantitative evaluation of the extracted OCPs after clean-up on silica gel were accomplished with the aid of a Gas Chromatography coupled with an Electron Capture Detector (GC-ECD. Levels of OCPs in cocoa beans from Ondo had a mean range of ND (p, p’-DDE to 82.17 ± 54.53 ng/g (p, p’-DDT were higher than the OCPs levels in cocoa beans from Ile-Ife with a mean range of 0.37 ± 0.63 ng/g (Endrin to 57.76 ± 81.48 ng/g (p, p’-DDT. The higher levels of OCPs detected in the cocoa beans from Ondo could be an indication of higher volume of OCPs application by cocoa farmers in Ondo and its environs since cocoa plantations were more concentrated than Ile-Ife environs. Levels of OCPs determined in the cocoa beans were within the Maximum Residue Limit (MRLs for OCPs set by the World Health Organization/Food and Agricultural Organization. The study established the presence of OCPs in an important crop of Nigeria. Hence, there is the need to keep monitoring ecotoxicological chemical substances in agricultural food products of Nigeria so as to take steps that ensure health safety of end users. Keywords: Pesticides, Organochlorine, Cocoa beans, Ondo, Ile-Ife, Nigeria

    15. La gouvernance des risques naturels et la problematique des ...

      African Journals Online (AJOL)

      Depuis quelques années, la gouvernance des risques naturels dus aux inondations remet en cause les processus de mise en oeuvre des politiques urbaines et la qualité de la structure des aménagements dans les grandes villes du Golfe de Guinée. La perception de la gouvernance et l'application des politiques de ...

    16. Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblasts

      International Nuclear Information System (INIS)

      Kim, Sang-in; Pfeifer, Gerd P.; Besaratinia, Ahmad

      2007-01-01

      Sunlight ultraviolet A (UVA) irradiation has been implicated in the etiology of human skin cancer. A genotoxic mode of action for UVA radiation has been suggested that involves photosensitization reactions giving rise to promutagenic DNA lesions. We investigated the mutagenicity of UVA in the lacI transgene in Big Blue mouse embryonic fibroblasts. UVA irradiation of these cells at a physiologically relevant dose of 18 J/cm 2 caused a 2.8-fold increase in the lacI mutant frequency relative to control, i.e., 12.12 ± 1.84 versus 4.39 ± 1.99 x 10 -5 (mean ± S.D.). DNA sequencing analysis showed that of 100 UVA-induced mutant plaques and 54 spontaneously arisen control plaques, 97 and 51, respectively, contained a minimum of one mutation along the lacI transgene. The vast majority of both induced- and spontaneous mutations were single base substitutions, although less frequently, there were also single and multiple base deletions and insertions, and tandem base substitutions. Detailed mutation spectrometry analysis revealed that G:C → T:A transversions, the signature mutations of oxidative DNA damage, were significantly induced by UVA irradiation (P -5 ; P < 0.00001). These findings are in complete agreement with those previously observed in the cII transgene of the same model system, and reaffirm the notion that intracellular photosensitization reactions causing promutagenic oxidative DNA damage are involved in UVA genotoxicity

    17. Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells.

      Science.gov (United States)

      Aoto, Kazushi; Sandell, Lisa L; Butler Tjaden, Naomi E; Yuen, Kobe C; Watt, Kristin E Noack; Black, Brian L; Durnin, Michael; Trainor, Paul A

      2015-06-01

      Neural crest cells (NCC) comprise a multipotent, migratory stem cell and progenitor population that gives rise to numerous cell and tissue types within a developing embryo, including craniofacial bone and cartilage, neurons and glia of the peripheral nervous system, and melanocytes within the skin. Here we describe two novel stable transgenic mouse lines suitable for lineage tracing and analysis of gene function in NCC. Firstly, using the F10N enhancer of the Mef2c gene (Mef2c-F10N) linked to LacZ, we generated transgenic mice (Mef2c-F10N-LacZ) that express LacZ in the majority, if not all migrating NCC that delaminate from the neural tube. Mef2c-F10N-LacZ then continues to be expressed primarily in neurogenic, gliogenic and melanocytic NCC and their derivatives, but not in ectomesenchymal derivatives. Secondly, we used the same Mef2c-F10N enhancer together with Cre recombinase to generate transgenic mice (Mef2c-F10N-Cre) that can be used to indelibly label, or alter gene function in, migrating NCC and their derivatives. At early stages of development, Mef2c-F10N-LacZ and Mef2c-F10N-Cre label NCC in a pattern similar to Wnt1-Cre mice, with the exception that Mef2c-F10N-LacZ and Mef2c-F10N-Cre specifically label NCC that have delaminated from the neural plate, while premigratory NCC are not labeled. Thus, our Mef2c-F10N-LacZ and Mef2c-F10N-Cre transgenic mice provide new resources for tracing migratory NCC and analyzing gene function in migrating and differentiating NCC independently of NCC formation. Copyright © 2015 Elsevier Inc. All rights reserved.

    18. Local gene regulation details a recognition code within the LacI transcriptional factor family.

      Directory of Open Access Journals (Sweden)

      Francisco M Camas

      2010-11-01

      Full Text Available The specific binding of regulatory proteins to DNA sequences exhibits no clear patterns of association between amino acids (AAs and nucleotides (NTs. This complexity of protein-DNA interactions raises the question of whether a simple set of wide-coverage recognition rules can ever be identified. Here, we analyzed this issue using the extensive LacI family of transcriptional factors (TFs. We searched for recognition patterns by introducing a new approach to phylogenetic footprinting, based on the pervasive presence of local regulation in prokaryotic transcriptional networks. We identified a set of specificity correlations--determined by two AAs of the TFs and two NTs in the binding sites--that is conserved throughout a dominant subgroup within the family regardless of the evolutionary distance, and that act as a relatively consistent recognition code. The proposed rules are confirmed with data of previous experimental studies and by events of convergent evolution in the phylogenetic tree. The presence of a code emphasizes the stable structural context of the LacI family, while defining a precise blueprint to reprogram TF specificity with many practical applications.

    19. Archive of Geosample Data and Information from the University of Minnesota National Lacustrine Core Repository (LacCore)

      Data.gov (United States)

      National Oceanic and Atmospheric Administration, Department of Commerce — The National Lacustrine Core Repository (LacCore), operated by the University of Minnesota is a partner in the Index to Marine and Lacustrine Geological Samples...

    20. EFFET DES TRAITEMENTS THERMIQUES SUR LA REACTION ENTRE DES COUCHES MINCES DE TITANE ET DES SUBSTRATS EN ACIER

      Directory of Open Access Journals (Sweden)

      D Slimani

      2015-06-01

      Full Text Available Des couches minces du titane pur ont été déposées avec la méthode de pulvérisation cathodique sur des substrats en acier, type FF80 K-1 contenants ~1% mass. en carbone. La réaction entre les deux parties du système substrat-couche mince est activée avec des traitements thermiques sous vide dans l’intervalle de températures de 400 à900°Cpendant 30 minutes. Les Spectres de diffraction de rayons x confirment l’inter- diffusion des éléments  chimiques du système résultants la formation et la croissance des nouvelles phases en particulier le carbure binaire TiC ayant des caractéristiques thermomécaniques importantes. L’analyse morphologique des échantillons traités  avec le microscope électronique à balayage (MEB montre l’augmentation du flux de diffusion atomique avec la température de recuit, notamment la diffusion du manganèse et du fer vers la surface libre des échantillons aux températures élevées provoquant la dégradation des propriétés mécaniques des revêtements contrairement au premiers stades d’interaction où on a obtenu des bonnes valeurs de la microdureté.

    1. Promouvoir l'entrepreneuriat inclusif des jeunes et des femmes ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Le projet vise à analyser la contribution réelle et potentielle de l'entrepreneuriat inclusif au bien-être des jeunes et des femmes en Côte d'Ivoire, au Burkina Faso et au Kenya. Après un état des lieux de la pratique de l'entrepreneuriat inclusif dans chacun des pays ciblés, l'équipe de recherche étudiera son incidence sur ...

    2. Trends in Marker and Non Marker elements along the horizontal distances of major and minor roads, Ile-Ife, Nigeria by PIXE

      International Nuclear Information System (INIS)

      Inyang, E. P.; Oketayo, O. O.; Obiajunwa, E. I.

      2011-01-01

      Determination of total elemental composition along the horizontal distances of both sides of major and minor roads in Ile- Ife is important because of the agricultural practices in the neighborhoods of the study area. Soil samples (0-15 cm) obtained from varying horizontal distances from both sides of major and minor roads in Ile-Ife were determined by PIXE method. Results showed a regular trend for the marker elements and irregular trend for the non marker elements. We hope that our findings may influence policy planning ofland usage especially for agriculture.

    3. El rol y significado de las lagunas Huaringas cerca de Huancabamba y el curanderismo en el Norte del Perú

      Directory of Open Access Journals (Sweden)

      1991-01-01

      Full Text Available LE ROLE ET LA SIGNIFICATION DES PETITS LACS HUARINGAS DANS LA PRATIQUE DES GUERISSEURS DU NORD DU PEROU. Cet article démontre la grande importance de certains petits lacs de montagne dans la pratique des guérisseurs du nord du Pérou. Parmi eux, les Huaringas de Huancabamba (Dept. de Piura sont les plus connus. Ces petits lacs sont dotés de pouvoirs ou vertus telluriques et cosmiques. Les guérisseurs les utilisent pour leurs traitements, les sorciers néfastes pour faire le mal. Un bain rituel dans un de ces lacs est le traitement le plus efficace. Les petits lacs sont vus comme des encantos qui sont essentiellement des lieux chargés de force et de pouvoir, et qui auraient été créé par les premiers incas. Leur nature est féminine et on les invoque en tant que reines enchanteresses, demoiselles, etc... On leur parle, on les conjure, on leur fait des offrandes, et si nécessaire, on apaise leur rage. Quelques uns de ces petits lacs sont en relation avec les montagnes au pied desquelles ils se trouvent et qui sont considérées comme masculines. Guardianes et différents autres esprits permettent d'accroître la force des lacs. Les herbes magiques qui y croissent déterminent leurs différentes vertus. Le 24 juin, fête de Saint Jean-Baptiste et jour du solstice d'hiver, est divisé en 3 étapes : d'abord un rite de salutation suivi d'invocations et d'offrandes, ensuite le bain proprement dit et enfin un rite final d'adieu. STRUGGLES AND CLAIMS OF THE YANACONAS IN THE PIURAN HIGHLAND HACIENDAS DURING THE YEARS 1934-1945. During 1934, the yanacona struggle begins within the Piura Highlands, demanding labor improvement and a fair ruling of the working conditions in the haciendas of the area. Members of the peruvian socialist party supported and advised all peasants over their claims. These people address their complaints to the Regional Working Inspectory in order to obtain a final solution to their labor conflicts. The study of such

    4. Report on radiotherapy organization in Ile-de-France

      International Nuclear Information System (INIS)

      Aoun, Andre; Nizri, Daniel; Chivot, Francois-Xavier

      2011-07-01

      Based on meetings with a large number of professional and experts, this report aimed at providing a view on the radiotherapy activity in all health establishments and independent laboratories, at analysing its organisation with respect to population needs, at proposing an answer on the short term to difficulties met by this care in some parts of different districts of Ile-de-France, and at bearing a specific attention to the issue of necessary collaborations in order to meet planning objectives. A first part analyses the treatment offer and actual health care for radiotherapy in the region: supply mapping (in terms of centres, medical and technical personnel), and analysis of patient flows in 2009 and 2010. It outlines challenges and formulates recommendations for an offer reorganisation by analysing the present access to radiotherapy offer, and by discussing a desirable offer in radiotherapy

    5. Assessment of aquifer properties, evapotranspiration, and the effects of ditching in the Stoney Brook watershed, Fond du Lac Reservation, Minnesota, 2006-9

      Science.gov (United States)

      Jones, Perry M.; Tomasek, Abigail A.

      2015-01-01

      The U.S. Geological Survey, in cooperation with the Fond du Lac Band of Lake Superior Chippewa, assessed hydraulic properties of geologic material, recharge, and evapotranspiration, and the effects of ditching on the groundwater resources in the Stoney Brook watershed in the Fond du Lac Reservation. Geologic, groundwater, and surface-water data were collected during 2006–9 to estimate hydrologic properties in the watershed. Streamflow and groundwater levels in the shallow glacial deposits in the Stoney Brook watershed were analyzed to estimate groundwater-flow directions, groundwater recharge, and evapotranspiration within the watershed and to assess the effect of ditches on surrounding groundwater resources. Groundwater, streamflow, and precipitation data collected during the study (2006–9) can be used to update the U.S. Department of Agriculture’s Natural Resource Conservation Service and Fond du Lac Resource Management Division surface-water models, which are used to evaluate the effect of proposed adjustments to the ditching system on streamflow on wild rice production and aquatic habitats.

    6. Prise en charge des urgences au service d'accueil des urgences ...

      African Journals Online (AJOL)

      Introduction: La prise en charge des patients dans les services d'accueil des urgences est une des meilleures vitrines d'un système de santé. En Afrique subsaharienne, la gestion des urgences se heurte à des difficultés humaines et matérielles. Le but de ce travail était d'évaluer les difficultés de prise en charge au Service ...

    7. methanization development in Ile-de-France - Ile-de-France region. Synthesis. The Regional Council strategy for methanization development

      International Nuclear Information System (INIS)

      2013-06-01

      A first document reports the study of methanization development in the Ile-de-France region by addressing biomass produced on the region territory. It aimed at identifying and assessing the existing and potential physical resource while introducing mobilisation rates in order to define different scenarios. A situational analysis of operated and projected methanization installations has also been performed. These projects have been classified according to a typology, and analysed according to the proposed scenarios. The position of methanization with respect to other biomass valorisation sectors, as well as the impact of mobilisation with respect to a return-to-soil of organic matters have also been discussed. A second document proposes a synthetic version of this study. The third document presents the Regional Council's policy and strategy regarding methanization development: challenges and prospective scenarios, importance of a sustainable methanization at the service of territory development, regulation for a call for projects, project assessment and selection, project footprint, inputs qualities and supplies, energetic and agronomic valorisation, and grid for project analysis. An appendix contains a synthetic version of the first document

    8. The NuSTAR view on Hard-TeV BL Lacs

      Science.gov (United States)

      Costamante, L.; Bonnoli, G.; Tavecchio, F.; Ghisellini, G.; Tagliaferri, G.; Khangulyan, D.

      2018-05-01

      Hard-TeV BL Lacs are a new type of blazars characterized by a hard intrinsic TeV spectrum, locating the peak of their gamma-ray emission in the spectral energy distribution (SED) above 2-10 TeV. Such high energies are problematic for the Compton emission, using a standard one-zone leptonic model. We study six examples of this new type of BL Lacs in the hard X-ray band with NuSTAR. Together with simultaneous observations with the Neil Gehrels Swift Observatory, we fully constrain the peak of the synchrotron emission in their SED, and test the leptonic synchrotron self-Compton (SSC) model. We confirm the extreme nature of 5 objects also in the synchrotron emission. We do not find evidence of additional emission components in the hard X-ray band. We find that a one-zone SSC model can in principle reproduce the extreme properties of both peaks in the SED, from X-ray up to TeV energies, but at the cost of i) extreme electron energies with very low radiative efficiency, ii) conditions heavily out of equipartition (by 3 to 5 orders of magnitude), and iii) not accounting for the simultaneous UV data, which then should belong to a different emission component, possibly the same as the far-IR (WISE) data. We find evidence of this separation of the UV and X-ray emission in at least two objects. In any case, the TeV electrons must not "see" the UV or lower-energy photons, even if coming from different zones/populations, or the increased radiative cooling would steepen the VHE spectrum.

    9. Connaissances, attitudes et pratiques des prestataires de santé des ...

      African Journals Online (AJOL)

      ... des prestataires interrogés avaient respectivement une bonne connaissance des facteurs de risque et des moyens de dépistage. Les signes évocateurs et les examens complémentaires nécessaires au diagnostic du cancer du sein étaient connus par 15,3 % des prestataires. La définition du cancer du sein et les moyens ...

    10. Quasi-simultaneous observations of BL Lac object Mrk 501 in X-ray, UV, visible, IR, and radio frequencies

      International Nuclear Information System (INIS)

      Kondo, Y.; Worrall, D.M.; Mushotzky, R.F.; Hackney, R.L.; Hackney, K.R.H.; Oke, J.B.; Yee, H.K.C.; Neugebauer, G.; Matthews, K.; Feldman, P.A.; Brown, R.L.

      1981-01-01

      Quasi-simultaneous observations of the BL Lac object Mrk 501 were performed for the first time at X-ray, ultraviolet, visible infrared, and radio frequencies. As the BL Lac objects are known to vary in their flux, such a ''quasi-instantaneous'' spectral energy profile is necessary in order to describe properly the energy generation mechanism. The observed spectral slope from the X-ray to UV regions is positive and continuous, but that from the mid-UV to visible light region becomes gradually flat and possibly turns down toward lower frequencies; the optical-radio emission cannot be accounted for by a single power law. Several theoretical models have been considered for the emission mechanism. In some cases quantitative comparison with the data is not practical. However, most of the models are, at least, not inconsistent with the observations. A quantitative comparison has been peformed with the synchroton self-Compton model; the total spectrum is found consistent with this model. The spectrum from visible light to X-ray is consistent with synchrotron radiation or with inverse-Compton scattering by a hot thermal cloud of electrons. The continuity of the spectral slope from X-ray to UV implied by the current data suggests that the previous estimates of the total luminosity of this BL Lac object has been underestimated by a factor of about 3 or 4

    11. No evidence for a role of Ile587Val polymorphism of EIF2B5 gene in multiple sclerosis in Kashmir Valley of India.

      Science.gov (United States)

      Zahoor, Insha; Asimi, Ravouf; Haq, Ehtishamul

      2015-12-15

      Multiple sclerosis (MS) is an inflammatory neurodegenerative disease of the nervous system with a profound genetic element. It is already known that alterations in Eukaryotic Translation Initiation Factor 2B (EIF2B) gene encoding the five subunits of eIF2B complex cause Vanishing White Matter (VWM) disease of the brain and emerging evidences have advocated certain resemblances between MS and VWM in terms of clinical and epidemiological characteristics, thus validating the association study between EIF2B and MS. Moreover, a recent study has implicated EIF2B5 Ile587Val (rs843358) polymorphism as a susceptibility factor for MS. In order to investigate the association of EIF2B5 Ile587Val polymorphism with MS susceptibility in Kashmir region in India, we screened EIF2B5 Exon 13 in 30 MS patients and 65 controls (a total of 95 participants). During the present course of study, we could not find statistically significant difference in the frequency of Ile587Val between MS patients and controls, thus indicating that such alteration does not appear to influence MS development in Kashmiri population. Our results provide evidence against a major role for Ile587Val polymorphism in MS susceptibility. Copyright © 2015 Elsevier B.V. All rights reserved.

    12. Remanso: the coexistence of time/space

      Directory of Open Access Journals (Sweden)

      Rosicleide Alves Moura

      1997-12-01

      Full Text Available Cet article met en valeur le quotidien et, ainsi, récupére l'histoire de vie, en la reproduisant dans le présent, comme une expérience pour la vie. II parle de la construction de 1' UHE de Sobradinho dont le lac a expulsé des milliers d' habitants du Nord baianais, 1' une des régions les plus sèches du Sertão Nordestino. II cherche à reconstituer cet espace de vie, soutenu par la combinaison fleuve-plaine-lacs-caatinga, gráce au savoir-faire, à la solidarité, à la sociabilité et à d'autres traits de 1' identité "sertaneja". Comment 1' État est le responsable por le développement inégal et des divergences des temporalités; comment les families dans d' autres espaces/temps vécus produisent et reproduisent de nouvelles/vieilles relations sociales, en créant le nouveau dans le vieux en le renouvelant, en 1' innovant. Enfin, cet article attire 1' attention sur l'innovation comme possibilité d' une praxis transformatrice à travers la reprise des mémoires de ceux qui ont éte expulsés en les réaffirmant comme des étres sociaux

    13. Usages des TIC et socialisation professionnelle des enseignants-chercheurs

      OpenAIRE

      Lavielle-Gutnik, Nathalie; Massou, Luc

      2013-01-01

      En prenant appui sur une nouvelle analyse des données recueillies dans l’enquête Tec-Meus (2008-2011, MSH Lorraine) sur la place accordée par des enseignants-chercheurs en sciences humaines et sociales aux technologies de l’information et de la communication (TIC) dans leur activité d’enseignement, nous souhaitons nous focaliser dans cet article sur la compréhension des processus de socialisation professionnelle en jeu dans leur usage déclaré des TIC. Par socialisation professionnelle, nous e...

    14. Evaluer des études de gestion des entreprises : combiner des éléments principales avec des éléments pratiques

      NARCIS (Netherlands)

      Pennink, B.J.W.

      2002-01-01

      Evaluer la recherche de gestion demande une combinaison des critères classiques et des critères pratiques. Par cette combinaison il est possible de trouver une réponse cerrecte concernant la validité et l'effet de la recherche. Dans cet article nous allons décrire comment une combinaison des

    15. Cadaveric Study of Male Lumbar Intervertebral Foramina Morphometry in Ile-Ife

      Directory of Open Access Journals (Sweden)

      Sunday E. C

      2018-04-01

      Full Text Available Background: This study was designed to investigate the mean lumbar foramina height and length in male cadaveric specimens in Ile-Ife. Aim and Objectives: Two hundred and fifty intervertebral foramina derived from twenty-five male cadaveric specimens were analyzed, were studied. They were obtained from the Department of Anatomy, Obafemi Awolowo University, Ile-Ife, Osun State in Southwestern Nigeria. The cadavers were positioned prone and a routine paraspinal approach was employed to gain exposure to the posterior spinal element following meticulous soft tissue dissection. An osteotomy of the iliac crest was performed to adequately expose the fifth lumbar (L1-S1 foramina.Parameters assessed were; the foramen height and the foraminal length. The measurement was performed three times on each side using vernier calipers. The variations of the different measurements in the cephalo-caudal direction were analyzed for statistical differences using the “One way ANOVA” with post hoc test. Results: The result showed a gradual increase of the foramina height were observed on both right and left side from L1-L2 to L3- L4 and from then on decreased progressively towards the L5-S1 level. No statistical difference was noted in the measurements derived (p<0.05. Conclusion: A good understanding of the lumbar intervertebral foraminal are essential in surgical planning of suitably sized cannulas necessary for less invasive spine surgeries as well as help in diagnosis of pathologies surrounding this important region following adequate clinical evaluation and measurements using imaging.

    16. Conduction block and tonic pupils in Charcot-Marie-Tooth disease caused by a myelin protein zero p.Ile112Thr mutation.

      LENUS (Irish Health Repository)

      Murphy, Sinéad M

      2011-03-01

      We report a patient with Charcot-Marie-Tooth disease (CMT) due to the p.Ile112Thr mutation in myelin protein zero (MPZ) who presented with a patchy neuropathy with conduction block and tonic pupils. Conduction block is unusual in inherited neuropathies, while pupil abnormalities are recognised to occur in CMT especially due to MPZ mutations. This case highlights that patchy demyelinating neuropathy with conduction block may occur in p.Ile112Thr MPZ mutations. Involvement of the pupils, as in this case, may be a pointer towards a genetic rather than inflammatory cause of neuropathy.

    17. Aspects des Onychomycoses chez des patients camerounais de ...

      African Journals Online (AJOL)

      ... biologiques et évolutifs des onychomycoses chez des patients camerounais. Méthode : Il s'agit d'une étude rétrospective et descriptive menée de mars 2011 à mars 2014 dans l'unité de dermatologie de l'hôpital général de Douala (HGD), incluant des patients chez lesquels le diagnostic d'onychomycose avait été posé.

    18. Radioisotopes in sedimentology; Emploi des radioelements en sedimentologie

      Energy Technology Data Exchange (ETDEWEB)

      Courtois, G [CEA, Centre d' etudes Nucleaires de Saclay (France)

      1967-05-15

      precipitation of sediment as a function of the physico-chemical characteristics of the water-bod y, and measurements of sediment density by means of back-scattering gauges. (author) [French] Les radioelements en sedimentologie trouvent emploi principalement dans deux grandes voies: l'etude de la dynamique des sediments en milieu fluvial et maritime et la mesure en continu de la quantite de sediments en suspension dans un milieu donne; ces deux questions sont examinees en detail et l'auteur decrit brievement quelques exemples d'autres applications n'entrant pas dans ces domaines. -Dynamique des sediments. Apres avoir rappele le principe de base de cette etude (injection dans le courant d'un sediment marque ou d'un simulateur suivie de la detection dans le temps du deplacement de l'activite), l'auteur fournit une liste aussi exhaustive que possible des problemes susceptibles d'etre resolus par l'emploi d'une telle technique. Ils sont essentiellement de deux types: 1) Les problemes lies au genie civil fluvial ou maritime: en mer, engravement de passes d'acces et de bassines, formation de bancs ou de barres, choix des points de rejet de sediments dragues, implantation de ports, protection des cotes, etc.; en riviere, orientation des prises d'eau des centrales hydroelectriques ou nucleaires, repercussion d'ouvrages sur le transport solide, installation de barrages, protection des berges, installation d'epis, comblement des lacs, etc. Dans les deux cas, mer et riviere, transport d'effluents et surtout tarage des modeles reduits. La bibliographie jointe comprend surtout des references relativement recentes et tient compte des travaux des groupes de chercheurs qui etudient actuellement le sujet. 2) Les problemes lies a la recherche fondamentale ou appliquee essentiellement mise en oeuvre par les universites et les centres de recherches: etude du quaternaire d'une region determinee, sedimentologie pure, recherche de grands courants de transports sedimentaires, confirmation ou

    19. SCADA Sistemi ile Bir İşletmenin Dış Saha Otomasyonu

      OpenAIRE

      Kılıç, Murat; Özdemir, Şule

      2010-01-01

      Bu çalışmada, PLC (Programmable Logic Controller: Programlanabilir Mantık Denetleyici) ve SCADA (Supervising Control and Data Acquisition: Veri Tabanlı Kontrol ve Gözetleme) sistemleriyle bir MDF (Medium Density Fiberboard) presi dış saha besleme hattının otomasyonu gerçekleştirilmiştir. Tüm sistem SCADA sayesinde bilgisayar ekranından izlenebilmekte ve kontrol edilebilmektedir. MDF presi dış saha besleme hattı tam otomasyon ile çalışmaktadır. Otomasyon sisteminde PLC yazılımı olarak Siemens ...

    20. Architecture, des normes et des systèmes d'information libres, phase ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Architecture, des normes et des systèmes d'information libres, phase II (OASIS II) - Renforcement des capacités dans l'ensemble de l'Afrique. Sur presque tout le continent africain, la prestation des services de santé est limitée en raison des maigres ressources disponibles et de la charge de morbidité de plus en plus ...

    1. Bazı Sert Çekirdekli Meyve Türlerinde Çiçek Tozu Çimlenmesi ve Çim Borusu Uzunluğunun Çoklu Regresyon Yöntemi ile Modellenmesi

      Directory of Open Access Journals (Sweden)

      Sultan Filiz GÜÇLÜ

      2015-11-01

      Full Text Available Ziraat ile ilgili çalışmalarda üretilen modeller birden fazla etkenin sonucu olarak ortaya çıkarlar. Bu tür modelleri ortaya çıkarmak için genelde kabul gören yöntemlerden biri de regresyon analizidir. Bu çalışma kapsamında 4 farklı türe ait birer çeşitte belirlenen çim borusu uzunluğu ve çimlenme oranı verileri, farklı sıcaklık ve zaman koşullarında, laboratuvar ortamında ölçülmüş ve bu ölçüm verileri kullanılarak çoklu regresyon yöntemi ile çiçek tozu çimlenme oranı ve çim borusu uzunluğu tahmin modelleri oluşturulmuştur. Modellerin performansı belirlilik katsayısı(R2 ve ortalama kare hata (RMSE değerlerine göre belirlenmiştir. Bu tahmin modellerinde elde edilen R2 değerleri, çim borusu uzunluğu tahmin modellerinde 0.69 ile 0.79 arasında, çimlenme oranı tahmin modellerinde ise 0.63 ile 0.90 arasında elde edilmiştir. RMSE değerleri, çimlenme oranı için; 6.15 ile 10.19 arasında, çim borusu uzunluğu için ise; 13.73 ile 21.3 arasında elde edilmiştir.

    2. Incidence of Bacterial Septicaemia in Ile-Ife Metropolis, Nigeria

      Directory of Open Access Journals (Sweden)

      Komolafe, A. O.

      2008-01-01

      Full Text Available A retrospective study of septicaemia was conducted in Ile-Ife metropolis with a view to determine its incidence and changes in the predominant aetiological agents. Six hundred and fifty (650 subjects, aged from one day to seventy years and above were examined. They all had clinical features suggestive of septicaemia and were on admission at the Obafemi Awolowo University hospital Complex, Ile-Ife, Nigeria. Their blood specimens were seeded into thioglycolate and glucose broths and incubated at 37 °C for 7 days. Subcultures were performed after 1, 2, 3, 4 and 7 days respectively. Growth (positivity in the broths was assessed using conventional diagnostic methods namely macroscopy (visualization, Gram filming (microscopy and culture. The bacterial isolates harvested were subjected to in-vitro antibiotic susceptibility tests using the disc diffusion method. Etiology was established in 204 out of 650 subjects indicating an incidence of 31.4%. This difference in prevalence among different age groups was statistically significant (P 0.01. Monomicrobial septicaemia had a higher prevalence (92.2% than polymicrobial septicaemia (7.8%. Staphylococcus aureus and Escherichia coli constituted 43.8%. Most of the offensive microbes were facultative anaerobes (91.7% while very few were strict aerobes (6.8% and strict anaerobes (1.5%. The isolated anaerobes were Peptostreptococcus sp. (0.5% and Bacteroides fragilis (1%. The in vitro susceptibility of the bacterial isolates to antibiotics indicated 76.4-95.6% sensitivity to vancomycin, zinnat, peflacin and fortum. However, they were 60 – 90% resistant to penicillin, ampicillin, tetracycline and septrin. This study confirmed the diverse nature of bacterial etiologies of septicaemia in the area; the need for the use of thioglycolate broths, first subcultures on or before 24 h instead of starting off for after 48 h of incubation, complementary application of macroscopy, Gram filming and culture including

    3. L'exode des cerveaux et le renforcement des capacités en Afrique ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      1 févr. 2011 ... Ce phénomène ébranle les assises économiques et politiques de bien des pays africains. ... le défi consiste à recruter ces cerveaux. ... des missions africaines, des organisations non gouvernementales et des groupes de la diaspora réunis pour parler de l'exode des cerveaux en Afrique et des stratégies à ...

    4. 1699-IJBCS-Article- Matias Fonteh

      African Journals Online (AJOL)

      hp

      Gestion intégrée des ressources en eau dans le bassin versant du lac ... En prélude à l'élaboration d'une stratégie de gestion durable de l'eau du ..... dynamique des ressources en eau à l'échelle ... régulièrement les contrôles de la qualité.

    5. Browse Title Index

      African Journals Online (AJOL)

      Vol 19, No 2 (2017): Special Issue, Gestion participative de la fertilite de sol en culture biologique d'Ananas comosus ((L.) Merrill) au Sud de la Republique du Benin ... Vol 17, No 2 (2015), Habiletes manageriales et de leadership et la performance des unites de soins primaires du district des Lacs au Togo Leadership and ...

    6. Influence de l'occupation des terres sur la dynamique des ...

      African Journals Online (AJOL)

      L'objectif de la présente étude est d'évaluer l'impact de mise en culture, des pâturages, des jachères et l'influence des villages sur la dynamique des communautés végétales de la commune de ..... mais il n'y a que peu de recrutement. Au-delà de cinq ans, taille et phytovolume diminuent, témoignant du vieillissement de la ...

    7. GENOMIQUE ET LIPIDES Génomique et métabolisme des lipides des plantes

      Directory of Open Access Journals (Sweden)

      Delseny Michel

      2002-03-01

      Full Text Available Il existe dans les bases de données publiques une énorme quantité de séquences d’ADN dérivées de plantes, et notamment la séquence complète du génome d’Arabidopsis thaliana, une plante modèle pour les oléagineux, proche parente du colza. Ces données constituent une ressource importante non seulement pour la compréhension de métabolisme lipidique et de sa régulation, mais aussi pour la sélection et le développement de variétés nouvelles d’oléagineux produisant davantage d’huiles ou des huiles de composition nouvelle. Cette abondance de séquences peut être exploitée, en utilisant les recherches d’homologies, pour identifier les gènes, pour obtenir des informations sur leur fonction, comme pour repérer des gènes candidats codant des fonctions nouvelles. L’analyse de ces bases de données a révélé que la majeure partie des gènes codant des enzymes impliquées dans le métabolisme lipidique appartient à des petites familles multigéniques, reflétant la diversification des fonctions des isoformes. Une analyse du catalogue des ADNc séquencés en aveugle reflète les niveaux d’expression des différents gènes et fournit un aperçu des régulations des flux au travers des voies métaboliques conduisant à la biosynthèse des lipides de réserve. La disponibilité de mutants et de lignées transgéniques d’Arabidopsis et le développement de puces à ADN qui permettent l’analyse simultanée de plusieurs milliers de gènes conduiront à une meilleure compréhension des facteurs qui régulent le métabolisme des huiles dans les graines. Une telle connaissance facilitera la manipulation de la composition des huiles et des quantités produites dans les graines.

    8. P-15: U-19 Futbol Takımı Oyuncularının Aerobik Kapasite ve Süratlerinin, Alt Ekstremite İzokinetik Kas Kuvveti ile İlişkilendirilmesi

      Directory of Open Access Journals (Sweden)

      Gökhan Deliceoğlu

      2017-03-01

      Full Text Available Araştırmanın amacını U-19 futbol takımı oyuncularının aerobik kapasite ve süratlerinin, alt ekstremite kuvveti ile ilişkilendirilmesi oluşturmaktadır. Araştırmaya U-19 kategorisindeki (Xyaş=18,17±0,53 yıl; Xva=73,16±5,95 kg; Xbu=178,22 ± 5,95 cm 15 futbolcu katıldı. Futbolcuların aerobik kapasiteleri Cosmed K5 © ile, alt ekstremite hamstring (H ve quadriseps (Q kas kuvvetleri ISOMED 2000 © İzokinetik Cihazı ile, sürat değerleri optojump © cihazı ile ölçüldü. Diz fleksör ve ekstansör kaslarının kas kuvveti 60°/sn açısal hızda 5 tekrarla, diz ekstansörlerinin kassal enduransı 180°/sn açısal hızda 30 tekrarla değerlendirildi. Futbolcular bir saat dinlendikten sonra, 10 dakika ısındı ve sonra ortalama hızın elde edilmesi için Optojump ile 30 m sürat testi iki kez uygulandı. Sporcular aerobik kapasitelerinin ölçülmesi için Cosmed K5 cihazı ile Bruce protokolünde koşturuldu. Futbolcuların maxVO2 ve ortalama hız değeri ile baskın ve baskın olmayan taraf diz fleksör ve ekstansör kaslarının kas kuvveti ile diz ekstansörlerinin kassal enduransı arasındaki ilişkinin belirlenmesi için SPSS 17,0’de regresyon analizi yapıldı. Analiz sonuçlarına göre, maxVO2 (X=51,84±7,56 ml/dk/kg ile baskın taraf 60 °/sn açısal hızdaki (Xfle=137,01 ±35,48 Nm; Xeks=239,26 ±57,96 Nm kuvvet değerleri arasında istatistiksel olarak anlamlı bir ilişki görüldü (R=759, R2=,576, p0.05. Futbolculardan elde edilen maxVO2 değerleri ile baskın olmayan taraf 60°/sn açısal hızdaki temel kas kuvveti (Xfle=140,62 ±34,11 Nm; Xeks=253,21 ±71,54 Nm ile 180/sn açısal hızda baskın taraf (X=66,86±8,16 ve baskın olmayan taraf kassal endurans (X=66,43±10,26 değerleri arasında anlamlı bir ilişki görülmedi (p>0.05. Futbolcularda baskın taraf diz fleksör ve ekstensör izokinetik kas kuvvet değerleri ile maxVO2 ve ortalama sürat değerleri arasında anlamlı bir ilişki g

    9. Des dispositions responsables à prendre pour la protection des ...

      African Journals Online (AJOL)

      En considérant l'effet néfaste des maladies, des parasites, du changement climatique et d'autres facteurs environnementaux (les OGM par exemple) sur la survie des abeilles, la baisse de leurs populations dans certaines parties du monde ne saurait être attribuée aux seules pesticides. En plus, l'impact de ces derniers sur ...

    10. Gestion des risques

      CERN Document Server

      Louisot, Jean-Paul

      2009-01-01

      Depuis le début du lie siècle, la gestion des risques connaît une véritable révolution culturelle. Jusqu'alors fonction technique, centrée autour de l'achat de couverture d'assurances, elle est devenue une discipline managériale et transversale : une valise d'instruments que chaque manager doit connaître et appliquer quels que soient son domaine de compétence et ses missions au sein de l'organisation. En effet, la gestion des risques est une culture qui doit être assimilée par chacun des acteurs. C'est précisément l'ambition des 101 questions rassemblées dans cet ouvrage : apporter à chaque manager d'entreprise, de collectivité, d'établissement de santé..., des réponses claires au " pourquoi " et au " comment " : Comment identifier les risques ? Comment analyser les risques ? Quels sont les objectifs de la gestion des risques ? Une carte des risques pour quoi faire ? Pourquoi faut-il financer les risques ? Les entreprises ont-elles des responsabilités pénales ? En quoi consiste la gestion...

    11. Comportement des polluants des eaux pluviales urbaines en ...

      African Journals Online (AJOL)

      développement et la croissance des organismes vivant dans l'eau et particulièrement les micro- organismes. Le suivi des températures enregistrées oscille entre 9 et 16°C dans les trois sites d'observation durant la période ... de la lumière du soleil. Le site C est bien aéré et .... Effets de différents modes de gestion des eaux ...

    12. Caractérisation des plantes médicinales à flavonoïdes des marchés ...

      African Journals Online (AJOL)

      Les espèces guinéo-congolaises sont les plus abondantes et le mode de dissémination majoritaire des diaspores est la zoochorie. Les plantes à flavonoïdes les plus utilisées sont : Combretum micranthum, Aloe vera, Ageratum conyzoïdes et Cylicodiscus gabonensis. Elles rentrent dans le traitement de 73 maladies parmi ...

    13. Association of Helicobacter pylori infection with Toll-like receptor-4 Thr399Ile polymorphism increased the risk of peptic ulcer development in North of Iran.

      Science.gov (United States)

      Tourani, Mehdi; Habibzadeh, Maryam; Shokri-Shirvani, Javad; Teymournejad, Omid; Mostafazadeh, Amrollah; Khafri, Soraya; Nouri, Hamid Reza

      2018-01-01

      Toll-like receptor-4 (TLR4) polymorphisms may influence host immune response against Helicobacter pylori (H. pylori). This study aimed to investigate whether TLR4 polymorphisms are associated with H. pylori susceptibility and risk of peptic ulcer development or not. The TLR4 + 3725 G/C polymorphism was studied using polymerase chain reaction with confronting two-pair primers (PCR-CTPP). In addition, TLR4 Asp299Gly and Thr399Ile polymorphisms were evaluated by PCR-restriction fragment length polymorphism (RFLP). There was no significant difference in TLR4 + 3725 G/C and Asp299Gly genotype frequencies between non-peptic ulcer (NPUD) and peptic ulcer (PUD) individuals in the context of peptic ulcer development and susceptibility to infection with H. pylori. Nevertheless, a significant association with increased risk for PUD development was observed for polymorphism TLR4 Thr399Ile [odds ratio (OR) = 4.2; 95% confidence interval (CI) = 1.35-13.26; p = 0.01]. Correspondingly, TLR4 Thr399Ile polymorphism was associated with H. pylori susceptibility (OR = 0.27; 95% CI = 0.08-0.88; p = 0.04). In addition, TLR4 Thr399Ile polymorphism increased 4.2-fold, the risk of peptic ulcer development in individuals infected by H. pylori carrying CT + TT genotype. Our results showed that TLR4 Thr399Ile polymorphism along with H. pylori infection may play critical roles in peptic ulcer development in North of Iran. © 2017 APMIS. Published by John Wiley & Sons Ltd.

    14. Impact de la preparation des anodes crues et des conditions de cuisson sur la fissuration dans des anodes denses

      Science.gov (United States)

      Amrani, Salah

      La fabrication de l'aluminium est realisee dans une cellule d'electrolyse, et cette operation utilise des anodes en carbone. L'evaluation de la qualite de ces anodes reste indispensable avant leur utilisation. La presence des fissures dans les anodes provoque une perturbation du procede l'electrolyse et une diminution de sa performance. Ce projet a ete entrepris pour determiner l'impact des differents parametres de procedes de fabrication des anodes sur la fissuration des anodes denses. Ces parametres incluent ceux de la fabrication des anodes crues, des proprietes des matieres premieres et de la cuisson. Une recherche bibliographique a ete effectuee sur tous les aspects de la fissuration des anodes en carbone pour compiler les travaux anterieurs. Une methodologie detaillee a ete mise au point pour faciliter le deroulement des travaux et atteindre les objectifs vises. La majorite de ce document est reservee pour la discussion des resultats obtenus au laboratoire de l'UQAC et au niveau industriel. Concernant les etudes realisees a l'UQAC, une partie des travaux experimentaux est reservee a la recherche des differents mecanismes de fissuration dans les anodes denses utilisees dans l'industrie d'aluminium. L'approche etait d'abord basee sur la caracterisation qualitative du mecanisme de la fissuration en surface et en profondeur. Puis, une caracterisation quantitative a ete realisee pour la determination de la distribution de la largeur de la fissure sur toute sa longueur, ainsi que le pourcentage de sa surface par rapport a la surface totale de l'echantillon. Cette etude a ete realisee par le biais de la technique d'analyse d'image utilisee pour caracteriser la fissuration d'un echantillon d'anode cuite. L'analyse surfacique et en profondeur de cet echantillon a permis de voir clairement la formation des fissures sur une grande partie de la surface analysee. L'autre partie des travaux est basee sur la caracterisation des defauts dans des echantillons d'anodes crues

    15. UV spectrum of the BL Lac object PKS 0521-36

      Energy Technology Data Exchange (ETDEWEB)

      Danziger, I.J. (European Southern Observatory, Garching (Germany, F.R.)); Bergeron, J. (Centre National de la Recherche Scientifique, 75 - Paris (France). Inst. d' Astrophysique); Fosbury, R.A.E. (Royal Greenwich Observatory, Hailsham (UK)); Maraschi, L.; Treves, A. (Consiglio Nazionale delle Ricerche, Milan (Italy). Lab. di Fisica Cosmica; Milan Univ. (Italy). Ist. di Fisica); Tanzi, E.G. (Consiglio Nazionale delle Ricerche, Milan (Italy). Lab. di Fisica Cosmica)

      1983-05-01

      Ultraviolet observations (1200 to 3000 A) with the IUE satellite of the BL Lac object PKS 0521-36 are presented. The only emission line which appears clearly in the spectrum is Ly..cap alpha.., which is asymmetric with a component displaced approx. 3000 km s/sup -1/ to the red. The intensity of the line and the upper limits on other lines are compared with the model calculations on QSOs and Seyfert nuclei by Kwan and Krolik. The continuous energy distribution is discussed, combining non-simultaneous observations from the ultraviolet to the infrared. The spectral range of the non-thermal source from far IR to far UV can be described by a single power law of index -1.5.

    16. Northern hemisphere mid-latitude geomagnetic anomaly revealed from Levantine Archaeomagnetic Compilation (LAC).

      Science.gov (United States)

      Shaar, R.; Tauxe, L.; Agnon, A.; Ben-Yosef, E.; Hassul, E.

      2015-12-01

      The rich archaeological heritage of Israel and nearby Levantine countries provides a unique opportunity for archaeomagnetic investigation in high resolution. Here we present a summary of our ongoing effort to reconstruct geomagnetic variations of the past several millennia in the Levant at decadal to millennial resolution. This effort at the Southern Levant, namely the "Levantine Archaeomagnetic Compilation" (LAC), presently consists of data from over 650 well-dated archaeological objects including pottery, slag, ovens, and furnaces. In this talk we review the methodological challenges in achieving a robust master secular variation curve with realistic error estimations from a large number of different datasets. We present the current status of the compilation, including the southern and western Levant LAC data (Israel, Cyprus, and Jordan) and other published north-eastern Levant data (Syria and southern Turkey), and outline the main findings emerging from these data. The main feature apparent from the new compilation is an extraordinary intensity high that developed over the Levant region during the first two millennia BCE. The climax of this event is a double peak intensity maximum starting at ca. 1000 BCE and ending at ca. 735 BCE, accompanied with at least two events of geomagnetic spikes. Paleomagnetic directions from this period demonstrate anomalies of up to 20 degrees far from the averaged GAD field. This leads us to postulate that the maximum in the intensity is a manifestation of an intense mid-latitude local positive geomagnetic anomaly that persisted for over two centuries.

    17. La cire cuticulaire des grains de raisin et des feuilles de la vigne

      Directory of Open Access Journals (Sweden)

      F. RADLER

      1968-06-01

      Full Text Available Je voudrais parler ici des recherches que j'ai effectuées dans le cadre d'un programme de recherches de l'Organisation australienne de recherches (C.S.I.R.O.. Ce sont des recherches sur la structure, la composition chimique et le rôle de la cire cuticulaire des grains de raisins et des feuilles. Ces recherches ont été effectuées principalement lors de l'étude des problèmes relatifs au séchage des raisins pour la production des raisins. Cependant, l'importance de la cire cuticulaire ne se limite pas seulement au séchage des raisins, car elle concerne aussi l'œnologie et les problèmes de la conservation des raisins de table. Je pense donc que mon exposé peut présenter pour vous un certain intérêt.

    18. Entre fermeture et perméabilité, analyse des contrôles d’accès des résidences sécurisées en France From closure to permeability: analysis of acces control  in french gated communities

      Directory of Open Access Journals (Sweden)

      Gérald Billard

      2012-06-01

      Full Text Available Le déploiement d’un arsenal sécuritaire (grille, portail, digicode, caméra, etc. est devenu depuis quelques années en France un élément central de nombreux produits mis sur le marché par les promoteurs immobiliers. Des travaux collectifs réalisés par Billard, Madoré (dir., Chevalier, Raulin, Taburet et Vuaillat – dans le cadre d’un contrat de recherche financé par l’Institut National des Hautes Études de Sécurité (2008 – montrent à la fois la diffusion nationale de ces offres immobilières sécurisées et leur banalisation dans certaines régions (Ile de France, Couloir rhodanien, Midi-Pyrénées, Côte d’Azur. Dans ces conditions, il apparaît légitime de s’interroger sur la fragmentation urbaine induite par la multiplication des enclaves fermées. Entre production de frontières imperméables, barrières symboliques ou partielles, et pragmatisme des résidents, le gradient de fermeture oscille d’une opération résidentielle à l’autre, complexifiant indéniablement la vision d’un espace urbain de plus en plus carcéral.    For several years, the display of a security arsenal (gate, fence, digicode, video-camera has become the central criterion for many new real estate operations. A collective study conducted by Billard, Madoré (dir., Chevalier, Raulin, Taburet and Vuaillat – financed by the Institut National des Hautes Etudes de Sécurité (2008 – shows the national spread of this kind of secured real estate products as well as their standardization in some french regions (Paris metropolitan area, Rhône Valley,  Midi-Pyrénées, French Riveria…. Regarding this situation, it would be appropriate to focus our attention on the urban fragmentation induced by this large implementation of gated communities. Due to the production of impassable frontiers, symbolic or partial gates and the pragmatism of the inhabitants, the degree of enclosure differs from one real estate offer to another, making

    19. Study feature of variability extragalactic radio sources 3C 446 and BL Lac in the centimeter wavelength range

      International Nuclear Information System (INIS)

      Sukharev, A.L.

      2015-01-01

      This work presents the results of the analysis of long-term monitoring (over 40 years) changes in radio fluxes of the two extragalactic sources - 3C 446, and BL Lac. Observations at frequencies of 14.5, 8, 4.8 GHz were obtained in the Michigan Radio Astronomy Observatory (UMRAO). With using Fourier filtering were selected 0- C (short-period), and the trend component of flux variations that were analyzed separately with using the wavelet-analysis method. Each of these components is associated with certain physical processes in the 'core-accretion disk-jet' system. Were constructed time-frequency wavelet-spectra showing the changes of the frequency composition of the investigated data over time. For the trend component values of the main periods of -4-9 years (3C 446) and -8 years (BL Lac), for 0- C component -0.8-3 years (3C 446) and -0.6-4 years (BL Lac) and they appear in the temporal and structural changes of the jet. On the basis of calculating the global wavelet-spectra in the frequency range identified main phases activity of radio sources. Obtained comparison between the dynamics of jets (Mojave VLBI images), and change the frequency spectral structure of the studied data. With bandpass wavelet filtering, flux components corresponding to the main periods in the spectra, were identified and also found the delay between the observation frequencies in spectral bands of these periods

    20. statut de la matiere organique des cambisols et des lixisols sous

      African Journals Online (AJOL)

      Administrateur

      L'étude vise à évaluer la matière organique des Cambisols et des Lixisols sous formations naturelles de longue durée en zone climatique nord-soudanienne et à établir, les relations entre ... sont supérieures à celles des sols des zones sahélienne et sud-soudanienne. ... globale a eu une corrélation positive avec le pH.

    1. Via Lyon: Parcours de romans et mutations éditoriales au XVIe siècle. Partie II. La circulation des textes entre Lyon et Paris

      Directory of Open Access Journals (Sweden)

      Gaëlle Burg

      2015-07-01

      Full Text Available La première partie du dossier Via Lyon (Carte Romanze 2/2 [2014] analysait le rôle de carrefour économique et culturel de la ville de Lyon dans la constitution d’une identité éditoriale des romans publiés en France au XVIe siècle. L’étude de ces «parcours de romans» conduit à replacer, en cette seconde partie du dossier, la notion d’«étape lyonnaise» dans la dynamique qui anime les deux principaux centres d’imprimerie français de la Renaissance. L’étude des pérégrinations éditoriales, de Paris à Lyon et de Lyon à Paris, de Lancelot du Lac (G. Burg, de Valentin et Orson (M. Colombo Timelli et de Méliadus chevalier de la Croix (A. Réach-Ngô met ainsi au jour les diverses formes de circulation, d’adaptation et de réappropriation que les ateliers parisiens et lyonnais confèrent aux œuvres romanesques qui passent sous leurs presses tout au long du siècle. The first part of the file Via Lyon (Carte Romanze 2/2 [2014] analyzed the role of economic and cultural crossroad of Lyon city in the constitution of an editorial identity of novels published in France in the sixteenth century. The study of these «novels’ route» leads to situate the concept of «Lyon step» in the dynamics which animates the two major French printing centers of the Renaissance. The editorial peregrinations, from Paris to Lyon and from Lyon to Paris, of three french novels, Lancelot du Lac (G. Burg, Valentin and Orson (M. Colombo Timelli and Méliadus chevalier de la Croix (A. Réach-Ngô, shows the various forms of circulation, adaptation and reappropriation that various Parisian and Lyon workshops give to novels they print throughout the century. 

    2. Fiabilité des structures mécaniques adaptatives: effet de la panne des actionneurs ou des capteurs sur la stabilité

      Science.gov (United States)

      Fall, H.; Charon, W.; Kouta, R.

      2002-12-01

      Ces dernières décennies, des activités significatives dans le monde étaient dirigées autour du contrôle actif. Le but de ces recherches était essentiellement d'améliorer les performances, la fiabilité et la sécurité des systèmes. Notamment dans le cas des structures soumises à des vibrations aléatoires. D'importants travaux ont été consacré à l'utilisation des “matériaux intelligents” comme capteurs et actionneurs. Cette article propose l'analyse de la fiabilité des systèmes mécaniques en étudiant les pannes des actionneurs ou des capteurs. L'effet de ces pannes sur la stabilité et la performance du système y est démontré. Les méthodologies de conception y sont rappelées. Des exemples numériques sont fournis à travers le contrôle d'un panneau sous chargement dynamique pour illustrer la méthode proposée.

    3. Detection of GSTM1, GSTT1 and the Ile105Val GSTP1 gene variants

      DEFF Research Database (Denmark)

      Buchard, Anders; Sanchez, Juan J.; Dalhoff, Kim

      2008-01-01

      We have developed a PCR multiplex method that in a fast, inexpensive and reliable manner can detect if a person has two, one or no GSTM1 and GSTT1 genes and which at the same time can detect the allelic status of the GSTP1 Ile105Val genetic variant. A total of 200 Danes, 100 Somalis and 100...

    4. Évaluation des émissions de gaz à effet de serre des filières de traitement et de valorisation des boues issues du traitement des eaux usées

      OpenAIRE

      Reverdy, A.L.; Pradel, M.

      2011-01-01

      / Ce rapport présente l'inventaire des différentes consommations énergétiques, en consommables et des GES pour chaque poste de traitement et de valorisation des boues issues du traitement des eaux usées.

    5. Farklı Eğim Açılarındaki Fotovoltaik Panellerin Elektriksel Ölçümlerinin Raspberry Pi ile İzlenmesi

      Directory of Open Access Journals (Sweden)

      Harun ÖZBAY

      2016-03-01

      Full Text Available Güneş enerjisinden elektrik enerjisi elde etmek için fotovoltaik (FV paneller kullanılmaktadır. FV panellerden elde edilen enerji, panellerin kurulduğu coğrafi konuma, mevsimsel değişimlere ve çevre koşullarına göre sürekli olarak değişiklik göstermektedir. Dolayısıyla FV panellerden maksimum güç elde edilmesi amacıyla panellerin optimum eğim açısının aylık, mevsimsel ve yıllık olarak değiştirilmesi gerekir. Bu çalışmada, farklı açılarda yerleştirilen FV paneller ile Bilecik ilinde güneş enerjisinden elde edilecek maksimum gücün hangi eğim açılarında gerçekleştiğinin tespiti için verilerin toplanması, kayıt altına alınması ve analiz çalışmaları Raspberry Pi (RPi üzerine kurulu web sunucu aracılığı ile gerçekleştirilmiştir. Bu amaç doğrultusunda FV panellerin gerilimleri gün boyunca ölçülmektedir. Ölçülen veriler analog-dijital dönüştürücü (mikrodenetleyici ile sayısal bilgiye çevrilmektedir. RPi ile sayısal bilgilerin her 10 dakikada bir ortalaması alınarak kendi hafıza ortamında saklama işlemi gerçekleştirilmektedir. Aynı zamanda RPi’ye kurulan Linux temelli Raspbian işletim sisteminde oluşturulan betik yardımıyla ve web ara yüzünden aynalama işlemi yapılarak verilerin bilgisayar ortamına kaydedilmesi ile yedekleme işlemi gerçekleştirilmektedir. Farklı eğim açılarındaki FV panellerden elde edilen elektriksel ölçümler RPi üzerine kurulu web sunucu aracılığıyla günün her saatinde canlı olarak izlenebilmektedir. Ayrıca elektriksel veriler aylık ve yıllık olarak tarih ve zaman bilgileri ile kayıt altına alınmaktadır. Geliştirilen sistemin kullanıcı ara yüzüne http://solar.bilecik.edu.tr adresinden ulaşılabilmektedir.

    6. Improving radiotherapy quality and safety: a common objective of A.S.N. and the Ile de France Regional Hospital Agency. Thoughts on successful cooperation in Ile de France

      International Nuclear Information System (INIS)

      Solier, N.

      2009-01-01

      Radiotherapy recent development in cancer treatment needs strong procedures and quality assessment to improve safety both for patients and professionals. In Ile de France territory, a coordinated action between ASN inspectors and medical doctors specialized in public health (MISP), working as civil servants in health administration, was initiated at the end of 2007. An inspection guideline was implemented in a workshop between ASN and Regional Hospital Agency (ARH). The MISP as health administrator has to verify if care organisation responds to treatment cancer regulatory framework: as a doctor he is authorized to access to patient records to know which treatment was chosen. He has to assure if the therapeutic guidelines are respected. His comprehensive approach is essentially patient-oriented. The MISP inspection coordinated with ASN inspectors is a very pertinent pluri-disciplinary approach, undeniably necessary in such a medical technic. The effectiveness of the radiotherapy pluri-disciplinary team is funded on sharing procedures and experiences, respecting different knowledge and practices in daily work. This on site audit'. seems to be very fertile both for the radiotherapy team, the MISP and ASN inspectors. Continuous quality improvement in radiotherapy in the Ile de France region is a fertile issue between ANS and ARH teams. Confronting knowledge and procedures during the 'on site audit' in a transparent way will contribute improving radiotherapy for the 30.000 Francilian patients which receive this treatment each year. This challenge is our main concern to facilitate the patients access to the best standards treatments. (author)

    7. Conflictos geopolíticos por el agua en las cuencas mineras del Departamento de Oruro, Bolivia

      OpenAIRE

      Miranda, Víctor Hugo Perales

      2010-01-01

      Dans cet article, nous analyserons les conflits géopolitiques entre les acteurs reliés à la pollution minière des sous-bassins du lac Poopo dans le département de Oruro dans le sud-ouest de la Bolivie. À cette occasion, nous procéderons à la caractérisation sociale et hydrologique des bassins et de ses acteurs et de l’interaction entre les acteurs sur une analyse de la territorialisation des espaces des sous-bassins. In this paper, it is analyzed geopolitical water conflicts between involv...

    8. Renforcement de l'autonomie des collectivités au moyen des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Cette subvention permettra au ministère des Communications et des Technologies de l'information de l'Égypte ainsi qu'au fonds spécial réservé aux TI de consolider le modèle actuel des clubs de TI en Égypte, par l'entremise de services d'assistance sur demande, d'activités de formation à l'intention du personnel des ...

    9. L' approche des options stratégiques des acteurs dans i' etude des relations tu travail

      OpenAIRE

      López Pino, Carmen Marina

      2011-01-01

      Faire une analyse de la proposition analytique développée par le MIT (Masachussetts Institute of Tecnology) inspirée du concept des options stratégiques pour I' objet de cet article. En premier lieu, les sujets traités seront la problematique des relations du travail et les découvertes fondamentales des différentes recherches de I' equipe du MIT. Après, I' étude fait une courte présentatión sur I' approche des systémes de Dunlop dont I' èquipe cherche améliorer. Ensuite, sont présentés...

    10. In vitro transcription accurately predicts lac repressor phenotype in vivo in Escherichia coli

      Directory of Open Access Journals (Sweden)

      Matthew Almond Sochor

      2014-07-01

      Full Text Available A multitude of studies have looked at the in vivo and in vitro behavior of the lac repressor binding to DNA and effector molecules in order to study transcriptional repression, however these studies are not always reconcilable. Here we use in vitro transcription to directly mimic the in vivo system in order to build a self consistent set of experiments to directly compare in vivo and in vitro genetic repression. A thermodynamic model of the lac repressor binding to operator DNA and effector is used to link DNA occupancy to either normalized in vitro mRNA product or normalized in vivo fluorescence of a regulated gene, YFP. An accurate measurement of repressor, DNA and effector concentrations were made both in vivo and in vitro allowing for direct modeling of the entire thermodynamic equilibrium. In vivo repression profiles are accurately predicted from the given in vitro parameters when molecular crowding is considered. Interestingly, our measured repressor–operator DNA affinity differs significantly from previous in vitro measurements. The literature values are unable to replicate in vivo binding data. We therefore conclude that the repressor-DNA affinity is much weaker than previously thought. This finding would suggest that in vitro techniques that are specifically designed to mimic the in vivo process may be necessary to replicate the native system.

    11. Kısa Mesafe RF Algılayıcı ile Telemetri Uygulaması

      Directory of Open Access Journals (Sweden)

      Muhammet Sinan BAŞARSLAN

      2016-03-01

      Full Text Available Bu çalışmada, Telemetri bir sistem ya da tesisin, uzaktan kablo veya kablosuz olarak izlenmesi ve/veya kontrol edilmesidir. Uygulama alanları olarak petrol, su veya gaz boru hatlarının izlenmesi, uydu ve telekom antenlerinin izlenmesi, içme veya atık su tesislerinin izlenmesi sayılabilir. Günümüzde çoğunlukla kablosuz (wireless haberleşme tercih edilmektedir. Kablosuz iletişim teknolojilerinden de en yaygın kullanılanları bluetooth, radyo modem cihazları, GSM sistemleridir.Haberleşme yapılacak olan arazi düz olmak zorunda değildir. Antenler arasında dağ, tepe vb. haberleşmeyi engelleyici unsurlar olsa bile repeater özellikli RF data modemler ile bu tür engeller aşılabilmektedir. Bu sayede noktalar arası uzaklıklar kilometrelerce olabilir.Sunulan uygulamada telemetri yöntemi ile bir model araca dair verilerin uzak bir noktada bulunan Android işletim sistemli bir mobil cihaz üzerinden izlenmesi gerçekleştirilmiştir. Uzaktan izleme işlemleri için kısa mesafe RF teknolojisi (433 MHz kullanılmıştır.

    12. Pyrheliometric determination of atmospheric turbidity in harmattan over Ile-Ife, Nigeria

      International Nuclear Information System (INIS)

      Adeyefa, Z.D.; Adedokun, J.A.

      1990-02-01

      Measurements of direct solar radiation intensity, using an Angstrom compensation pyrheliometer carried out over three harmattan seasons (1985-1987) at Ile-Ife (7.29N, 4.34E) Nigeria, have been used to determine atmospheric turbidity based on five different models of turbidity, viz: Schuepp (B), Angstrom (β), Kastrov (C), Unsworth (τ a ) and Linke (T). The five parameters indicate high aerosol loading of the atmosphere during the period and high correlation is established between them: (0.919 ≤ τ ≤ 0.999). An inverse relationship has been noticed between horizontal visibility and atmospheric turbidity: (-0.80 ≤ τ ≤ -0.76). (author). 35 refs, 15 figs, 4 tabs

    13. Developpement des betons semi autoplacants a rheologie adaptee pour des infrastructures

      Science.gov (United States)

      Sotomayor Cruz, Cristian Daniel

      Au cours des dernières décennies, les infrastructures canadiennes et québécoises comportent plusieurs structures en béton armé présentant des problèmes de durabilité dus aux conditions climatiques sévères, à la mauvaise conception des structures, à la qualité des matériaux, aux types des bétons choisis, aux systèmes de construction ou à l'existence d'événements incontrôlables. En ce qui concerne le choix du béton pour la construction des infrastructures, une vaste gamme de béton divisée en deux principaux types peut être utilisée: le béton conventionnel vibré (BCV) et le béton autoplaçant (BAP). Dans le cas d'un BCV, la consolidation inadéquate par vibration a été un problème récurrent, occasionnant des dommages structuraux. Ceci a conduit à une réduction de la durabilité et à une augmentation du coût d'entretien et de réparation des infrastructures. Rien que l'utilisation d'un BAP a des avantages tels que l'élimination de la vibration, la réduction des coûts de main d'oeuvre et l'amélioration de la qualité des structures, néanmoins, le coût initial d'un BAP par rapport à un BCV ne permet pas encore de généraliser son utilisation dans l'industrie de la construction. Ce mémoire présente la conception d'une nouvelle gamme de béton semi-autoplaçant pour la construction des infrastructures (BSAP-I) exigeant une vibration minimale. Il s'agit de trouver un équilibre optimal entre la rhéologie et le coût initial du nouveau béton pour conférer une bonne performance structurale et économique aux structures. Le programme expérimental établi a premièrement permis d'évaluer la faisabilité d'utilisation des BSAP-I pour la mise en place des piliers d'une infrastructure de pont à Sherbrooke. En plus, l'utilisation d'un plan d'expériences a permis l'évaluation de trois paramètres de formulation sur les propriétés des mélanges de BSAP-I à l'état frais et durci. Finalement, l'évaluation de la performance des

    14. Soya Fasulyesi Ürünleri ile Beslenme Hedeflerine Ulaşılması (İngilizce

      Directory of Open Access Journals (Sweden)

      Levent Bayındırlı

      2015-02-01

      Full Text Available Genelde, hayvansal kaynaklı proteinler elzem amino asitlerin tümünü içerirken, bitkisel kaynaklı olanlar bu amino asitlerin bir veya birkaçından yoksundurlar. Soya proteinleri ise hayvansal kaynaklı proteinlerin besleyici değerini taşımakla birlikte daha ucuz fiyatlarla tüketime sunulması mümkündür. Bu çalışmada soya fasulyesinin gıda sistemlerindeki rolü, beslenme açısından bebeklerin, çocukların ve yaşlıların beslenmesinde; damar sertliği ve diğer bazı durumlarda kullanılması ile bu konudaki olası gelecek araştırmaların gereği tartışılmıştır. Dolayısıyla, dünyada proteine olan ihtiyaç ve bu ihtiyacın soya ürünleri ile karşılanabilmesi vurgulanmaya çalışılmıştır.

    15. Libération des acides gras par autolyse enzymatique des triglycérides des graines oléoprotéagineuses

      Directory of Open Access Journals (Sweden)

      Alibert Gilbert

      2001-01-01

      Full Text Available Les acides gras produits par hydrolyse chimique des lipides des plantes sont des matériaux de base pour l’industrie des biocarburants, des lubrifiants, des plastiques, des détergents et également des adjuvants de préparations commerciales d’herbicides. Cependant les procédés actuels de production des acides gras sont hautement polluants et coûteux en énergie. Dans ce travail nous développons un nouveau procédé de production des acides gras mettant en œuvre des plantes génétiquement modifiées. Nous avons introduit dans le tabac, retenu comme plante modèle, une construction génétique comprenant un gène de lipase (de la levure Geotrichum candidum sous le contrôle d’un promoteur graine spécifique (promoteur AtEm1 d’Arabidopsis thaliana. Ce promoteur devrait permettre l’expression du gène de lipase au niveau de l’axe embryonnaire tandis que les lipides s’accumulent dans les corps lipidiques des cotylédons. Dans ces conditions, les lipides de la graine devraient être séparés de la lipase par une compartimentation tissulaire et ne pas interférer. Après broyage des graines on peut penser que la mise en contact des lipides et de la lipase conduira à la libération d’acides gras. Plusieurs transformants ont été produits par transfert de gène à l’aide d’Agrobacterium tumefaciens, quelques-uns d’entre eux exprimant, comme attendu, la lipase dans leurs graines. Trois clones (2, 19 et 43 présentent une activité lipase significative et ont été retenus pour des études complémentaires. Cependant l’activité enzymatique observée est faible et certains clones présentent un défaut de compartimentation entre l’enzyme et les lipides se traduisant par la production d’acides gras dans la graine intacte. Lorsque les graines du clone 43 sont broyées dans un tampon, des acides gras sont produits dans le milieu réactionnel, validant le procédé imaginé. De nouvelles constructions réalisées, soit

    16. Andean glacial lakes and climate variability since the last glacial maximum

      Directory of Open Access Journals (Sweden)

      1995-01-01

      Full Text Available LES LACS GLACIAIRES ET LA VARIABILITÉ CLIMATIQUE DANS LES ANDES DEPUIS LE DERNIER MAXIMUM GLACIAIRE. Des carottages réalisés dans des lacs glaciaires des Andes tropicales et subtropicales ont fourni des registres paléoclimatiques continus couvrant le Dernier Maximum Glaciaire et l’Holocène. Des datations 14C sur sédiments lacustres et sur tourbes indiquent que le maximum de la dernière glaciation s’est produit antérieurement au Dernier Maximum Glaciaire Global (18 ka BP. La plupart des lacs ont un âge inférieur à 13 ka BP, ce qui signifie que l’avancée des glaciers correspondant au Pleistocène terminal aurait culminé aux alentours de 14 ka BP. Des avancées durant le Tardi-glaciaire sont enregistrées dans plusieurs sites lacustres. À partir de 10 ka BP, les glaciers ont reculé au-delà de leurs limites actuelles. La sécheresse de l’Holocène moyen est repérée dans la stratigraphie de nombre de lacs, y compris le lac Titicaca. Cette phase d’aridité est suivie par une remontée des niveaux lacustres et une réavancée des glaciers à la fin de l’Holocène. LAGOS GLACIARES ANDINOS Y VARIABILIDAD CLIMÁTICA DESDE EL ÚLTIMO MÁXIMO GLACIAL. Testigos de sedimentos de los lagos glaciares en los Andes tropicales/subtropicales proporcionan registros continuos de los paleoclimas del último glacial superior y del Holoceno. Dataciones del radiocarbón de los sedimentos profundos en los lagos y de las turberas indican que el máximo del último glacial fue antes del máximo glacial global con una fecha de 18 14C ka BP. La mayoría de los lagos tienen una antigüedad menor de 13 14C ka BP, lo que significa que hubo una fase de glaciación del Pleistoceno superior culminada alrededor de 14 14C ka BP. Los avances durante el glacial superior son indicados en varios testigos de sedimentos de los lagos y, después de 10 14C ka BP, los glaciares quedaron dentro de sus límites actuales. Una sequía durante el Holoceno medio est

    17. Residues in the H+ Translocation Site Define the pKa for Sugar Binding to LacY†

      Science.gov (United States)

      Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Choe, Jun-Yong; Kaback, H. Ronald

      2009-01-01

      A remarkably high pKa of approximately 10.5 has been determined for sugar-binding affinity to the lactose permease of Escherichia coli (LacY), indicating that, under physiological conditions, substrate binds to fully protonated LacY. We have now systematically tested site-directed replacements for the residues involved in sugar binding, as well as H+ translocation and coupling, in order to determine which residues may be responsible for this alkaline pKa. Mutations in the sugar-binding site (Glu126, Trp151, Glu269) markedly decrease affinity for sugar but do not alter the pKa for binding. In contrast, replacements for residues involved in H+ translocation (Arg302, Tyr236, His322, Asp240, Glu325, Lys319) exhibit pKa values for sugar binding that are either shifted toward neutral pH or independent of pH. Values for the apparent dissociation constant for sugar binding (Kdapp) increase greatly for all mutants except neutral replacements for Glu325 or Lys319, which are characterized by remarkably high affinity sugar binding (i.e., low Kdapp) from pH 5.5 to pH 11. The pH dependence of the on- and off-rate constants for sugar binding measured directly by stopped-flow fluorometry implicates koff as a major factor for the affinity change at alkaline pH and confirms the effects of pH on Kdapp inferred from steady-state fluorometry. These results indicate that the high pKa for sugar binding by wild-type LacY cannot be ascribed to any single amino acid residue but appears to reside within a complex of residues involved in H+ translocation. There is structural evidence for water bound in this complex, and the water could be the site of protonation responsible for the pH dependence of sugar binding. PMID:19689129

    18. 77 FR 27245 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN

      Science.gov (United States)

      2012-05-09

      ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N069; FXRS1265030000S3-123-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN AGENCY: Fish and... plan (CCP) and environmental assessment (EA) for Big Stone National Wildlife Refuge (Refuge, NWR) for...

    19. Paternité des articles et intérêts concurrents : une analyse des recommandations aux auteurs des journaux traitant de pratique pharmaceutique

      Science.gov (United States)

      Courbon, Ève; Tanguay, Cynthia; Lebel, Denis; Bussières, Jean-François

      2014-01-01

      RÉSUMÉ Contexte : La présence d’auteurs honorifiques et fantômes ainsi que les intérêts concurrents représentent des difficultés bien documentées, liées à la publication d’articles scientifiques. Il existe des lignes directrices encadrant la rédaction et la publication de manuscrits scientifiques, notamment celles de l’International Committee of Medical Journal Editors (ICMJE). Objectifs : L’objectif principal de cette étude descriptive et transversale visait à recenser les instructions portant sur la paternité des articles et les intérêts concurrents provenant des recommandations aux auteurs des journaux traitant de pratique pharmaceutique. L’objectif secondaire visait à déterminer des mesures correctrices pour une paternité des articles plus transparente. Méthode : La recherche a débuté par l’identification des journaux traitant de pratique pharmaceutique. La consultation des instructions aux auteurs des journaux a permis ensuite de recenser les recommandations destinées à éviter les problèmes de paternité des articles et d’intérêts concurrents. Finalement, les membres de l’équipe de recherche se sont consultés afin de définir des mesures correctrices possibles à l’intention des chercheurs. Résultats : Des 232 journaux traitant de pharmacie, 33 ont été définis comme traitant de pratique pharmaceutique. Un total de 24 (73 %) journaux mentionnaient suivre la politique de l’ICMJE, 14 (42 %) demandaient aux auteurs de remplir un formulaire de déclaration d’intérêts concurrents au moment de la soumission de l’article, 17 (52 %) présentaient une définition de la qualité d’auteur et 5 (15 %) demandaient de détailler les contributions de chaque auteur. Une grille de 40 critères a été élaborée pour définir l’attribution du statut d’auteur. Conclusion : Moins de la moitié des journaux demandait aux auteurs de transmettre un formulaire de déclaration des intérêts concurrents au moment de la

    20. Îles et continents

      OpenAIRE

      Resztak, Karolina; Sanson, Hervé

      2017-01-01

      Ce numéro huit de la revue Continents manuscrits, à l’enseigne des « Iles et continents », se veut un numéro de varias, une fois n’est pas coutume. Iles et continents car : du Congo aux Antilles, en passant par l’Amérique du Nord, le numéro assume sa géographie plurielle, polycentrée. Le panorama d’auteurs représentés dans la revue est riche et varié : de Joseph Zobel à Sony Labou Tansi, d’Aimé Césaire à Nathanaël, ou René Maran, c’est bien des cartographies mises en relation que ce numéro té...

    1. Contribution des radios communautaires a l'education des ...

      African Journals Online (AJOL)

      Contribution des radios communautaires a l'education des populations rurales pour un developpement durable au Benin: etude de cas. ... Journal de la Recherche Scientifique de l'Université de Lomé. Journal Home · ABOUT THIS JOURNAL ...

    2. Rôle des germes parasites des bactéries pathogènes dans l'autoépuration des eaux

      Directory of Open Access Journals (Sweden)

      GUELIN A.

      1969-04-01

      Full Text Available Existence dans les eaux polluées de germes parasites qui s'attaquent aux bactéries pathogènes. Le pouvoir bactéricide des eaux polluées dû, en grande partie à la présence dans ces eaux de différents représentants des germes parasites. Possibilité d'application pratique des germes parasites pour l'assainissement des eaux polluées.

    3. An Analysis of Periodic Components in BL Lac Object S5 0716 +714 with MUSIC Method

      Science.gov (United States)

      Tang, J.

      2012-01-01

      Multiple signal classification (MUSIC) algorithms are introduced to the estimation of the period of variation of BL Lac objects.The principle of MUSIC spectral analysis method and theoretical analysis of the resolution of frequency spectrum using analog signals are included. From a lot of literatures, we have collected a lot of effective observation data of BL Lac object S5 0716 + 714 in V, R, I bands from 1994 to 2008. The light variation periods of S5 0716 +714 are obtained by means of the MUSIC spectral analysis method and periodogram spectral analysis method. There exist two major periods: (3.33±0.08) years and (1.24±0.01) years for all bands. The estimation of the period of variation of the algorithm based on the MUSIC spectral analysis method is compared with that of the algorithm based on the periodogram spectral analysis method. It is a super-resolution algorithm with small data length, and could be used to detect the period of variation of weak signals.

    4. Source, flux and balance of atmospheric deposition of metals at Ile-de-France; Source, flux et bilan des retombees atmospheriques de metaux en Ile de France

      Energy Technology Data Exchange (ETDEWEB)

      Azimi, S

      2004-07-15

      The urban atmosphere is submitted to large inputs of anthropogenic contaminants arising from both stationary (power plants, industries, etc.) and mobile (road traffic) sources. These small particles may be transported over long distances and affect ecosystems. Significant dry and wet atmospheric deposition also occurs locally and contributes to the contamination of urban runoff. The aim of this study is to compare heavy metal and hydrocarbon atmospheric deposition fluxes to other input ways on agricultural and urban areas to assess their importance. Moreover, a source investigation has been done to identify the main origins of these pollutants. Before the quantification of pollutant fluxes, a comparison of several sampling procedures was performed. As a result, the sampling of total atmospheric deposition is not affected by the funnel material (Teflon and polyethylene) or by the sampling duration (7 and 28 days). However, the rinsing step of the funnel walls showed a higher relative importance during short sampling periods. The relative amount contained in these solutions reached 24 to 40 % of the total flux during weekly sampling periods and 8 to 18 % during monthly sampling periods, whatever the element considered. The temporal evolution of atmospheric deposition showed no seasonal influence on flux variations during the 2001-2002 period. Considering an 8-year period behaviour, between 1994 and 2002, a significant decrease of the deposition fluxes of Cd, Cu, Pb and Zn occurred at the Creteil site which is placed in an industrialized area of the Paris suburb. The decreasing factor reached 16, 2.5, 4 and 7.5 for these elements respectively. At the Ile-de-France scale, the deposition flux levels on urban and semi-urban areas were of the same order of magnitude (?20 tonnes per year for Ba, Cu, Pb and Sr). Since semi-urban surface area is four times higher than urban ones, the important influence of anthropogenic activities on atmospheric deposition of urban areas is

    5. Effets des extraits vegetaux sur la dynamique de populations des ...

      African Journals Online (AJOL)

      La présente étude se propose de trouver une alternative de l'utilisation des pesticides chimiques en testant l'effet insecticide des extraits aqueux des feuilles de Hyptis suaveolens, graines de Ricinus communis et de Azadirachta indica contre les ravageurs du niébé en conditions de champ en utilisant le cyperméthrine ...

    6. La participation des femmes à la vie politique se traduit par des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      La participation des femmes à la vie politique se traduit par des économies locales plus vigoureuses. 08 juin 2016. Image. Des femmes assistent à une réunion d'un groupe d'entraide près d'. Edgard Rodriguez - IDRC. Des femmes assistent à une réunion d'un groupe d'entraide près d'Hyderabad, en Inde. Keenara ...

    7. Incidence des prix et des taxes sur la consommation de produits du ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Incidence des prix et des taxes sur la consommation de produits du tabac en Argentine, en Bolivie et au Chili. Partout en Amérique du Sud, les adultes et les enfants font une grande consommation de tabac. Un nouveau projet de recherche se penchera sur les avantages et les limites des stratégies de fixation des prix et de ...

    8. Bistable behavior of the lac operon in E. coli when induced with a mixture of lactose and TMG

      Directory of Open Access Journals (Sweden)

      Orlando Díaz-Hernández

      2010-07-01

      Full Text Available In this work we investigate multistability in the lac operon of Escherichia coli when it is induced by a mixture of lactose and the non-metabolizable thiomethyl galactoside (TMG. In accordance with previously published experimental results and computer simulations, our simulations predict that: (1 when the system is induced by TMG, the system shows a discernible bistable behavior while, (2 when the system is induced by lactose, bistability does not disappear but excessively high concentrations of lactose would be required to observe it. Finally, our simulation results predict that when a mixture of lactose and TMG is used, the bistability region in the extracellular glucose concentration vs. extracellular lactose concentration parameter space changes in such a way that the model predictions regarding bistability could be tested experimentally. These experiments could help to solve a recent controversy regarding the existence of bistability in the lac operon under natural conditions.

    9. Bistable behavior of the lac operon in E. coli when induced with a mixture of lactose and TMG.

      Science.gov (United States)

      Díaz-Hernández, Orlando; Santillán, Moisés

      2010-01-01

      In this work we investigate multistability in the lac operon of Escherichia coli when it is induced by a mixture of lactose and the non-metabolizable thiomethyl galactoside (TMG). In accordance with previously published experimental results and computer simulations, our simulations predict that: (1) when the system is induced by TMG, the system shows a discernible bistable behavior while, (2) when the system is induced by lactose, bistability does not disappear but excessively high concentrations of lactose would be required to observe it. Finally, our simulation results predict that when a mixture of lactose and TMG is used, the bistability region in the extracellular glucose concentration vs. extracellular lactose concentration parameter space changes in such a way that the model predictions regarding bistability could be tested experimentally. These experiments could help to solve a recent controversy regarding the existence of bistability in the lac operon under natural conditions.

    10. Ser80Ile mutation and a concurrent Pro25Leu variant of the VHL gene in an extended Hungarian von Hippel-Lindau family

      Directory of Open Access Journals (Sweden)

      Fazakas Ferenc

      2008-04-01

      Full Text Available Abstract Von Hippel-Lindau disease (VHL is a rare autosomal dominant disease characterized by development of cystic and tumorous lesions at multiple sites, including the brain, spinal cord, kidneys, adrenals, pancreas, epididymis and eyes. The clinical phenotype results from molecular abnormalities of the VHL tumor suppressor gene, mapped to human chromosome 3p25-26. The VHL gene encodes two functionally active VHL proteins due to the presence of two translational initiation sites separated by 53 codons. The majority of disease-causing mutations have been detected downstream of the second translational initiation site, but there are conflicting data as to whether few mutations located in the first 53 codons, such as the Pro25Leu could have a pathogenic role. In this paper we report a large Hungarian VHL type 2 family consisting of 32 members in whom a disease-causing AGT80AAT (Ser80Ile c.239G>A, p.Ser80Ile mutation, but not the concurrent CCT25CTT (Pro25Leu c.74C>T, p.Pro25Leu variant co-segregated with the disease. To our knowledge, the Ser80Ile mutation has not been previously described in VHL type 2 patients with high risk of pheochromocytoma and renal cell cancer. Therefore, this finding represents a novel genotype-phenotype association and VHL kindreds with Ser80Ile mutation will require careful surveillance for pheochromocytoma. We concluded that the Pro25Leu variant is a rare, neutral variant, but the presence such a rare gene variant may make genetic counseling difficult.

    11. Roles et taches des accompagnateurs des patients hospitalises ...

      African Journals Online (AJOL)

      Roles et taches des accompagnateurs des patients hospitalises dans le service de pneumo-phtysiologie au Centre Hospitalier Universitaire Yalgado Ouedraogo de ... Logistical support represented by material support, drug supply, cleaning of premises, and littering occupied respectively 100%, 91%, 42% and 73%.

    12. Contribution to the study of protein deficiency: Use of radioisotope techniques; Contribution a l'etude des etats de malnutrition proteique utilisation de méthodes isotopiques

      Energy Technology Data Exchange (ETDEWEB)

      Dubois, J.; Colard, J.; Vis, H. L. [Université libre de Bruxelles, Brussels (Belgium); Centre d' étude de l' énergie nucléaire, Mol (Belgium)

      1970-01-15

      Research methods based on the use of radioisotopes have already been used for some time to study the physiopathogenesis of malnutritional and denutritional conditions in childhood. Two very specific aspects of malnutrition are studied primarily by means of these techniques: plasma protein metabolism proper and hydroelectrolytic disorders, which are an integral part of the physiopathogenetic picture of the disease. The authors have attempted, in so far as is possible, to define the clinical condition of children from along Lake Kivu, in the east of Kivu Province, who are suffering from protein and calorie deficiency. (author) [French] Les méthodes d'investigation à l'aide de radioisotopes ont été, depuis un certain temps déjà, utilisées pour l'étude de la physiopathogénie des états de malnutrition et de dénutrition de l'enfance. Deux aspects bien particuliers de la malnutrition sont surtout étudiés à l'aide de ces méthodes: le métabolisme propre des protéines plasmatiques et les troubles hydro-électrolytiques qui font partie intégrante du tableau physiopathogénique de l'affection. Les auteurs ont essayé de définir, le mieux possible, l'état clinique des enfants de l'est de la province du Kivu, le long du lac Kivu, souffrant de malnutrition protéo-calorique. (author)

    13. Utilisation des mousses et des pâtes syntactiques pour combler les lacunes des poteries archéologiques

      Directory of Open Access Journals (Sweden)

      Viviane Bechoux

      2008-10-01

      Full Text Available Filling potteries missing parts with plaster raises now complex problems during the de-restoration treatments. Ceramics restorers have recurrently questions on the use of plaster in the field of archaeological ceramics restoration. Some researches point to the choice of other filling materials. At the present time other methods can be devised by proposing plaster replacement by a lightened composite material: syntactic foams and pastes.Le comblement des lacunes des poteries à partir du plâtre pose actuellement des problèmes complexes lors des traitements de dérestauration. Les restaurateurs de céramiques s'interrogent de manière récurrente sur l'utilisation du plâtre dans le domaine de la restauration des céramiques archéologiques. Des recherches s'orientent vers le choix d'autres matériaux d'obturation. Actuellement, d'autres méthodes peuvent être mises en place en proposant le remplacement du plâtre par un matériau composite allégé, les mousses et les pâtes syntactiques.

    14. Développer le leadership dans des villes de l'Amérique latine et des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Développer le leadership dans des villes de l'Amérique latine et des Caraïbes dans le contexte des changements climatiques. En raison des changements climatiques, de la croissance démographique et de l'urbanisation rapide non planifiée, les villes des pays en développement sont à la fois le principal déclencheur des ...

    15. La Question de L'impunité des Auteurs de Violations des Droits de L'homme

      Directory of Open Access Journals (Sweden)

      Maria dos Remédios Fontes Silva

      2010-10-01

      Full Text Available Ce travail pretend faire reflechir à propos de la question de l'impunite des autorites de L'Etat face aux violations des droits de l'homme. On abordera cet egard: a le role de I'amnistie ble complicite des autoritesadministratives c la lenteur des procedures judicieuse.     L'analyse de cette question montre qui L'impunite des responsables des violations des droits de l'homme fait peser une menace sur I'ensemble du systeme de protection universelle des droits de l'homme.          On peut on conduire qu 'aucune societe que aspire à la democratie et ala justice ne peut se construire sur I'amoralite des crimes impunis et I'amnesie officielle.

    16. Characterisation and discrimination of various types of lac resin using gas chromatography mass spectrometry techniques with quaternary ammonium reagents.

      Science.gov (United States)

      Sutherland, K; del Río, J C

      2014-04-18

      A variety of lac resin samples obtained from artists' suppliers, industrial manufacturers, and museum collections were analysed using gas chromatography mass spectrometry (GCMS) and reactive pyrolysis GCMS with quaternary ammonium reagents. These techniques allowed a detailed chemical characterisation of microgram-sized samples, based on the detection and identification of derivatives of the hydroxy aliphatic and cyclic (sesquiterpene) acids that compose the resin. Differences in composition could be related to the nature of the resin, e.g. wax-containing (unrefined), bleached, or aged samples. Furthermore, differences in the relative abundances of aliphatic hydroxyacids appear to be associated with the biological source of the resin. The diagnostic value of newly characterised lac components, including 8-hydroxyacids, is discussed here for the first time. Identification of derivatised components was aided by AMDIS deconvolution software, and discrimination of samples was enhanced by statistical evaluation of data using principal component analysis. The robustness of the analyses, together with the minimal sample size required, make these very powerful approaches for the characterisation of lac resin in museum objects. The value of such analyses for enhancing the understanding of museum collections is illustrated by two case studies of objects in the collection of the Philadelphia Museum of Art: a restorer's varnish on a painting by Luca Signorelli, and a pictorial inlay in an early nineteenth-century High Chest by George Dyer. Copyright © 2014 Elsevier B.V. All rights reserved.

    17. Membrane fluidization by alcohols inhibits DesK-DesR signalling in Bacillus subtilis.

      Science.gov (United States)

      Vaňousová, Kateřina; Beranová, Jana; Fišer, Radovan; Jemioła-Rzemińska, Malgorzata; Matyska Lišková, Petra; Cybulski, Larisa; Strzałka, Kazimierz; Konopásek, Ivo

      2018-03-01

      After cold shock, the Bacillus subtilis desaturase Des introduces double bonds into the fatty acids of existing membrane phospholipids. The synthesis of Des is regulated exclusively by the two-component system DesK/DesR; DesK serves as a sensor of the state of the membrane and triggers Des synthesis after a decrease in membrane fluidity. The aim of our work is to investigate the biophysical changes in the membrane that are able to affect the DesK signalling state. Using linear alcohols (ethanol, propanol, butanol, hexanol, octanol) and benzyl alcohol, we were able to suppress Des synthesis after a temperature downshift. The changes in the biophysical properties of the membrane caused by alcohol addition were followed using membrane fluorescent probes and differential scanning calorimetry. We found that the membrane fluidization induced by alcohols was reflected in an increased hydration at the lipid-water interface. This is associated with a decrease in DesK activity. The addition of alcohol mimics a temperature increase, which can be measured isothermically by fluorescence anisotropy. The effect of alcohols on the membrane periphery is in line with the concept of the mechanism by which two hydrophilic motifs located at opposite ends of the transmembrane region of DesK, which work as a molecular caliper, sense temperature-dependent variations in membrane properties. Copyright © 2017 Elsevier B.V. All rights reserved.

    18. Photonique des Morphos

      CERN Document Server

      Berthier, Serge

      2010-01-01

      La photonique est déjà présente dans notre vie quotidienne, et on attend maintenant que la manipulation des photons permette aussi le traitement logique des informations. Cependant, l’élément de base qui permet cette manipulation de la lumière, le cristal photonique, est d’une réalisation complexe et mal contrôlée. Dans la course à la maîtrise de la lumière, les structures photoniques naturelles ont beaucoup à nous apprendre. C’est ce que nous montre Serge Berthier qui étudie dans ce livre la structure des écailles des Morphos. Tenant compte de l’essor récent des approches biomimétiques, il présente de manière détaillée plus de dix-huit techniques expérimentales utilisées pour ses analyses, ainsi que les diverses approches théoriques développées pour la modélisation de structures multi-échelles complexes. Première étude quasi-exhaustive des structures fines d’un genre et des propriétés optiques ainsi que colorimétriques générées, ce livre fournit aux entomologiste...

    19. Screening phytochimique et identification spectroscopique des ...

      African Journals Online (AJOL)

      Origin

      plante, effectuée pour la première fois, a révélé la présence des alcaloïdes, des flavonoïdes, des tanins catéchiques, des terpènes, des coumarines et des composés cyanogénétiques. Quant aux saponines et les quinones libres, ils sont présents chez les fleurs et absents chez les feuilles. La caractérisation des molécules.

    20. Lac du Flambeau Band of Lake Superior Chippewa Indians Strategic Energy Plan

      Energy Technology Data Exchange (ETDEWEB)

      Bryan Hoover

      2009-11-16

      This plan discusses the current energy use on the Lac du Flambeau Reservation, the current status of the Tribe's energy program, as well as the issues and concerns with energy on the reservation. This plan also identifies and outlines energy opportunities, goals, and objectives for the Tribe to accomplish. The overall goal of this plan is to address the energy situation of the reservation in a holistic manner for the maximum benefit to the Tribe. This plan is an evolving document that will be re-evaluated as the Tribe's energy situation changes.

    1. Etude du processus de changement vecu par des familles ayant decide d'adopter volontairement des comportements d'attenuation des changements climatiques

      Science.gov (United States)

      Leger, Michel T.

      Les activites humaines energivores telles l'utilisation intensive de l'automobile, la surconsommation de biens et l'usage excessif d'electricite contribuent aux changements climatiques et autres problemes environnementaux. Bien que plusieurs recherches rapportent que l'etre humain est de plus en plus conscient de ses impacts sur le climat de la planete, ces memes recherches indiquent qu'en general, les gens continuent a se comporter de facon non ecologique. Que ce soit a l'ecole ou dans la communaute, plusieurs chercheurs en education relative a l'environnement estiment qu'une personne bien intentionnee est capable d'adopter des comportements plus respectueux de l'environnement. Le but de cette these etait de comprendre le processus d'integration de comportements d'attenuation des changements climatiques dans des familles. A cette fin, nous nous sommes fixe deux objectifs : 1) decrire les competences et les procedes qui favorisent l'adoption de comportements d'attenuation des changements climatiques dans des familles et 2) decrire les facteurs et les dynamiques familiales qui facilitent et limitent l'adoption de comportements d'attenuation des changements climatiques dans des familles. Des familles ont ete invitees a essayer des comportements personnels et collectifs d'attenuation des changements climatiques de sorte a integrer des modes de vie plus ecologiques. Sur une periode de huit mois, nous avons suivi leur experience de changement afin de mieux comprendre comment se produit le processus de changement dans des familles qui decident volontairement d'adopter des comportements d'attenuation des changements climatiques. Apres leur avoir fourni quelques connaissances de base sur les changements climatiques, nous avons observe le vecu de changement des familles durant huit mois d'essais a l'aide de journaux reflexifs, d'entretiens d'explicitation et du journal du chercheur. La these comporte trois articles scientifiques. Dans le premier article, nous presentons une

    2. L'accumulation des métaux lourds au niveau des cultures : Cas des ...

      African Journals Online (AJOL)

      Le Bassin de Sebou présente une importance socio-économique pour le Maroc. En effet, il est sujet de diverses utilisations ; eau potable, eau d'irrigation et eau industrielle. Toutefois, ce bassin subit des pressions multiples, notamment par la pollution métallique. Considérant le risque de bioaccumulation des métaux par ...

    3. Search for relation between flares and photometric variability outside of flares in EV Lac

      International Nuclear Information System (INIS)

      Rojzman, G.Sh.

      1984-01-01

      The observations of the flare star EV Lac in July-September 1981 have confirmed the existence of photometric variability outside the flares during the night. It was found that, as a rule, a slow increase of brightness in U and B bands during 1-2 hours preceded the flares. It is suggested that the variability outside the flares is the result of the variability of chpomospheric emission lines and continuum that are emitted by the chromospheric preflare formations

    4. Low-temperature heat capacity and thermodynamic properties of [Re{sub 2}(Ile){sub 4}(H{sub 2}O){sub 8}](ClO{sub 4}){sub 6} (Re=Nd, Er, Ile=isoleucine)

      Energy Technology Data Exchange (ETDEWEB)

      Lan Xiaozheng; Tan Zhicheng; Liu Beiping; Nan Zhaodong; Sun Lixian; Xu Fen

      2003-06-03

      The heat capacities of two kinds of rare-earth element solid complexes with isoleucine [Re{sub 2}(Ile){sub 4}(H{sub 2}O){sub 8}](ClO{sub 4}){sub 6} (where Re=Nd, Er, and Ile=isoleucine) have been measured by an automatic adiabatic calorimeter in the temperature range from 80 to 370 K. Two solid-solid phase transitions were found from the C{sub p} curve of Nd formed complex in the range of 165-175 K with a peak temperature of 167.88 K and in the range of 195-210 K with a peak temperature of 202.13 K. The corresponding molar enthalpies of these phase transitions were determined to be 404.61 J mol{sup -1} and 2.955 kJ mol{sup -1}, respectively. One solid-solid phase transition was found for the Er formed complex in the range of 190-205 K with a peak temperature of 193.42 K. The corresponding molar enthalpy of this transition was 14.11 kJ mol{sup -1}. Smooth heat capacities and thermodynamic functions relative to the standard state (298.15 K), H{sub T}-H{sub 298.15}, S{sub T}-S{sub 298.15} and -[G{sub T}-G{sub 298.15}], of the two compounds, were calculated on basis of experimental heat capacity data. Possible mechanisms of thermal decompositions for the pair of compounds were suggested according to the thermogravimetric (TG) analysis.

    5. Contrôle des Circuits Auxiliaires des PFW (arrêt machines 2002/2003)

      CERN Document Server

      Ottaviani, J

      2003-01-01

      Les PFW sont des nappes polaires installées sur les pôles des aimants du PS. Elles sont au nombre de 4 par unité d aimant et constituées d un circuit principal (dans lequel circule le courant désiré selon le cycle magnétique utilisé) et de circuits auxiliaires. Les circuits auxiliaires sont des enroulements de correction (boucles de tour et pick-up brasés sur les enroulements). Pendant la variation du champ magnétique de l aimant PS, on utilise des tensions induites dans ces circuits auxiliaires pour corriger les erreurs de champ dues aux courants de Foucault dans la chambre à vide. Chaque année, pendant l arrêt machine, on vérifie si les caractéristiques des circuits auxiliaires correspondent aux normes (mesures des résistances des boucles de tours, résistances entre pick-up et isolation des circuits) afin de faire un suivi. Les 404 PFW sont ainsi vérifiées. Dans cette note, on ne relèvera que les PFW ayant des défauts (valeurs hors tolérances, boucles ouvertes ou en court-circuit, déf...

    6. 794-IJBCS-Article-Chouti Waris

      African Journals Online (AJOL)

      DR GATSING

      poissons souvent signalée par les pêcheurs. MATERIEL ET METHODES. Prélèvement des échantillons. Six points de prélèvements ont été choisis en tenant compte des déversements domestiques, eaux de ruissellement et apport du Lac Nokoué (Figure 1). Les campagnes de prélèvements sont effectuées suivant les.

    7. Journal de la Recherche Scientifique de l'Université de Lomé - Vol ...

      African Journals Online (AJOL)

      Decentralisation et politiques budgetaires sportives dans les communes du Benin ... Problematique d'une gestion intercommunale du lac aheme et ses chenaux · EMAIL ... Relations entre la pme et ses partenaires : une analyse des difficultes ...

    8. The UV spectrum of the BL Lac object PKS 0521-36

      International Nuclear Information System (INIS)

      Danziger, I.J.; Bergeron, J.; Maraschi, L.; Treves, A.; Milan Univ.; Tanzi, E.G.

      1983-01-01

      Ultraviolet observations (1200 to 3000 A) with the IUE satellite of the BL Lac object PKS 0521-36 are presented. The only emission line which appears clearly in the spectrum is Lyα, which is asymmetric with a component displaced approx. 3000 km s - 1 to the red. The intensity of the line and the upper limits on other lines are compared with the model calculations on QSOs and Seyfert nuclei by Kwan and Krolik. The continuous energy distribution is discussed, combining non-simultaneous observations from the ultraviolet to the infrared. The spectral range of the non-thermal source from far IR to far UV can be described by a single power law of index -1.5. (author)

    9. Various mutations compensate for a deleterious lacZα insert in the replication enhancer of M13 bacteriophage.

      Directory of Open Access Journals (Sweden)

      Emily M Zygiel

      Full Text Available M13 and other members of the Ff class of filamentous bacteriophages have been extensively employed in myriad applications. The Ph.D. series of phage-displayed peptide libraries were constructed from the M13-based vector M13KE. As a direct descendent of M13mp19, M13KE contains the lacZα insert in the intergenic region between genes IV and II, where it interrupts the replication enhancer of the (+ strand origin. Phage carrying this 816-nucleotide insert are viable, but propagate in E. coli at a reduced rate compared to wild-type M13 phage, presumably due to a replication defect caused by the insert. We have previously reported thirteen compensatory mutations in the 5'-untranslated region of gene II, which encodes the replication initiator protein gIIp. Here we report several additional mutations in M13KE that restore a wild-type propagation rate. Several clones from constrained-loop variable peptide libraries were found to have ejected the majority of lacZα gene in order to reconstruct the replication enhancer, albeit with a small scar. In addition, new point mutations in the gene II 5'-untranslated region or the gene IV coding sequence have been spontaneously observed or synthetically engineered. Through phage propagation assays, we demonstrate that all these genetic modifications compensate for the replication defect in M13KE and restore the wild-type propagation rate. We discuss the mechanisms by which the insertion and ejection of the lacZα gene, as well as the mutations in the regulatory region of gene II, influence the efficiency of replication initiation at the (+ strand origin. We also examine the presence and relevance of fast-propagating mutants in phage-displayed peptide libraries.

    10. Contribution des TICs à l'abandon des mutilations génitales ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Contribution des TIC à l'abandon des MGF en Afrique de l'Ouest francophone : rôle des jeunes citoyennes; rapport technique no. 5 (rapport technique final), 18 octobre 2008 - 31 mars 2009. Download PDF. Related content. New website will help record vital life events to improve access to services for all. A new website ...

    11. utilisation des donnees pour l'evaluation de l'heterogeneite des sols

      African Journals Online (AJOL)

      AISA

      étude a permis de caractériser l'hétérogénéité des sols ferrallitiques, à travers sa couleur. Mots-clés : Couleur ... ainsi qu'à l'application des recommandations des doses de fertilisant. ..... de « système sol » en zone de contact forêt- savane du ...

    12. Impact of intimate partner violence on anxiety and depression amongst women in Ile-Ife, Nigeria.

      Science.gov (United States)

      Mapayi, Boladale; Makanjuola, R O A; Mosaku, S K; Adewuya, O A; Afolabi, O; Aloba, O O; Akinsulore, A

      2013-02-01

      Research into intimate partner violence in the Nigerian environment has been limited. The objective of this study was to determine, amongst a sample of women attending the Enuwa Primary Health Care Center, Ile-Ife, the association between intimate partner violence and anxiety/depression. A descriptive cross-sectional study was conducted amongst 373 women who attended the antenatal clinic and welfare units of a primary health centre in Ile-Ife using the Composite Abuse Scale, the Hospital Anxiety and Depression Scale and a socio-demographic scale as instruments. Slightly over a third (36.7 %) reported intimate partner violence within the past year, 5.6 % had anxiety and 15.5 % were depressed. Anxiety and depression in the respondents were significantly associated with intimate partner violence. Women were ten times more likely to report being depressed and 17 times more likely to report anxiety if they were in violent relationships. This research has shown that the magnitude of intimate partner violence within the study population is comparable to those found in the developing countries. There are significant associations between intimate partner violence, anxiety and depression amongst the study population and this fact undoubtedly has implications for the mental health of the Nigerian woman.

    13. Bird communities of contrasting semi-natural habitats of Lac bay, Bonaire, during the fall migration season, 2011

      NARCIS (Netherlands)

      Debrot, A.O.; Bemmelen, van R.S.A.; Ligon, J.

      2013-01-01

      The mangrove and seagrass lagoon of Lac Bay on Bonaire covers an area of roughly 700 ha. It is home to endangered green sea turtles, Chelonia mydas, and the Caribbean queen conch, Strombus gigas, and is a roosting and breeding area for several birds. Based on its nature values this 7 km2 bay has

    14. Intelligent Local Avoided Collision (iLAC) MAC Protocol for Very High Speed Wireless Network

      Science.gov (United States)

      Hieu, Dinh Chi; Masuda, Akeo; Rabarijaona, Verotiana Hanitriniala; Shimamoto, Shigeru

      Future wireless communication systems aim at very high data rates. As the medium access control (MAC) protocol plays the central role in determining the overall performance of the wireless system, designing a suitable MAC protocol is critical to fully exploit the benefit of high speed transmission that the physical layer (PHY) offers. In the latest 802.11n standard [2], the problem of long overhead has been addressed adequately but the issue of excessive colliding transmissions, especially in congested situation, remains untouched. The procedure of setting the backoff value is the heart of the 802.11 distributed coordination function (DCF) to avoid collision in which each station makes its own decision on how to avoid collision in the next transmission. However, collision avoidance is a problem that can not be solved by a single station. In this paper, we introduce a new MAC protocol called Intelligent Local Avoided Collision (iLAC) that redefines individual rationality in choosing the backoff counter value to avoid a colliding transmission. The distinguishing feature of iLAC is that it fundamentally changes this decision making process from collision avoidance to collaborative collision prevention. As a result, stations can avoid colliding transmissions with much greater precision. Analytical solution confirms the validity of this proposal and simulation results show that the proposed algorithm outperforms the conventional algorithms by a large margin.

    15. Bromate and trace metal levels in bread loaves from outlets within Ile-Ife Metropolis, Southwestern Nigeria

      Directory of Open Access Journals (Sweden)

      J.A.O. Oyekunle

      2014-01-01

      Full Text Available Bread loaves randomly sampled from nine outlets and bakeries within Ile-Ife were analysed to determine their safety levels for human consumption with respect to bromate and trace metal contents. Bromate determination was carried out via spectrophotometric method while trace metals in the digested bread samples were profiled using Flame Atomic Absorption Spectrophotometer. Bromate levels in the analyzed bread samples ranged from 2.051 ± 0.011 μg/g to 66.224 ± 0.014 μg/g while the trace metal levels were of the order: 0.03–0.10 μg/g Co = 0.03–0.10 μg/g Pb < 0.23–0.46 μg/g Cu < 2.23–6.63 μg/g Zn < 25.83–75.53 μg/g Mn. This study revealed that many bread bakers around Ile-Ife had not fully complied with the bromate-free rule stipulated by NAFDAC contrary to the “bromate free” inscribed on the labels of the bread. The bread samples contained both essential and toxic trace metals to levels that could threaten the health of consumers over prolonged regular consumption.

    16. Organization of intervention in case of a nuclear accident on the Ile Longue nuclear submarine base

      International Nuclear Information System (INIS)

      Laroche, P.; Doussot, P.; Rousset, J.

      2003-01-01

      When a nuclear accident has occurred, intervention teams have to work out the actions in order to limit results of accident on personnel, installations and environment. Initial stage, that begin applying special cards, allows to organize command and rescue, and brings intervention teams on the accident site. Intervention is composed of three stages: victims' rescue, struggle against conflagration, and technical support to the damaged structure. The diversity of teams allows to carry out these operations at the same time. According as personnel is injured or able bodied, decontamination is carried out in specific structure. Victims' rescue is a priority. Casualties are treated in the Ile Longue treatment center of technical shelters (CTBRC/ETNI). Able-bodied people in the area of accident have to reach refuges immediately after the alarm. They are presumed contaminated and first are checked in the advanced command station. Then they are evacuated, after a stage station, to the large capacity decontamination and triage center, where treatment and control can be effectuated; the evacuation is now possible. Some of them are treated in the Ile Longue contamination treatment center in case of internal or obstinate contamination. (author)

    17. An Analysis of Light Periods of BL Lac Object S5 0716+714 with the MUSIC Algorithm

      Science.gov (United States)

      Tang, Jie

      2012-07-01

      The multiple signal classification (MUSIC) algorithm is introduced to the estimation of light periods of BL Lac objects. The principle of the MUSIC algorithm is given, together with a testing on its spectral resolution by using a simulative signal. From a lot of literature, we have collected a large number of effective observational data of the BL Lac object S5 0716+714 in the three optical wavebands V, R, and I from 1994 to 2008. The light periods of S5 0716+714 are obtained by means of the MUSIC algorithm and average periodogram algorithm, respectively. It is found that there exist two major periodic components, one is the period of (3.33±0.08) yr, another is the period of (1.24±0.01) yr. The comparison of the performances of periodicity analysis of two algorithms indicates that the MUSIC algorithm has a smaller requirement on the sample length, as well as a good spectral resolution and anti-noise ability, to improve the accuracy of periodicity analysis in the case of short sample length.

    18. Les lexiques des jeunes dans les discours écrits des blogs : pour une approche descriptive

      Directory of Open Access Journals (Sweden)

      Lorenz Paulina

      2014-07-01

      Full Text Available S’il ne faut pas confondre ce qui est appelé communément « langage SMS » et « langage des jeunes », nous avancerons toutefois que les pratiques langagières écrites des jeunes sur les supports modernes de communication, et notamment dans les blogs, présentent des particularités encore peu étudiées. Les traits observables les plus saillants sont ceux de la morphologie graphique, mais il n’en reste pas moins que certains jeunes utilisent des lexiques particuliers dans les blogs qui méritent une attention particulière. Nous nous proposons donc d’étudier les différents lexiques utilisés par des jeunes de 12 à 22 ans dans les blogs de la plateforme skyrock.com aux niveaux de sa diversité, de ses usages sémantiques variable d’un scripteur à l’autre pour un même mot, et de ses particularités morphosyntaxiques. En effet, nous observerons des lexiques divers allant des lexiques perçus comme relevant des cités à des lexiques perçus comme étant « branchés-jeunes », ou encore à des lexiques propres aux supports modernes de communication. Ainsi, nous analyserons des lexiques variés dans leurs usages écrits tels que bolos, bédave, gérer, ouf, tigen, ou encore des lexiques empruntés tels que mouv, full, etc., ainsi que des emplois particuliers de séquences autonomes comme lol. Quelques questions périphériques complèteront notre analyse telle que celles qui concerne l’influence des usages lexicaux entre pairs et le savoir partagé, la distinction de différentes communautés en fonction des lexiques utilisés, ou encore la variabilité des représentations graphiques d’un même mot.

    19. Radio emission from quasars and BL Lac objects by coherent plasma oscillation and stimulated Compton scattering

      International Nuclear Information System (INIS)

      Colgate, S.A.; Petschek, A.G.

      1978-01-01

      The full radiation spectrum of quasars and BL Lac objects is interpreted as due to a dependent combination of a soft plasma oscillation source at 2ν/sub P/ and bremsstrahlung. Previous work of the plasma oscillation radiation is extended into the radio part of the spectrum and it is shown how the high brightness temperature observations of BL Lac objects [kT/sub b/ (100 MHz) approximate = 3 x 10 5 mc 2 ] are a reasonable consequence of a lower external plasma density and ejection as required for the observed lack of emission lines. Two extreme cases are considered, the one where the plasma oscillations are suddenly extinguished and only stimulated Compton scattering remains and a second case of a constant source of plasma oscillations but a graded surface density. The first case gives 1/100 of the required brightness temperature and the second gives 100 times too large a brightness temperature and also a x 10 too large a radius. It is believed reasonable to invoke a combination of both processes to explain the observed radio spectrum. This model circumvents the self-Compton x-ray flux difficulty of incoherent synchrotron emission

    20. Hydrogen production by Escherichia coli {delta}hycA {delta}lacI using cheese whey as substrate

      Energy Technology Data Exchange (ETDEWEB)

      Rosales-Colunga, Luis Manuel; Ordonez, Leandro G.; De Leon-Rodriguez, Antonio (Division de Biologia Molecular, Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la Presa San Jose 2055, Col. Lomas 4a secc. CP 78216, San Luis Potosi, SLP. Mexico); Razo-Flores, Elias; Alatriste-Mondragon, Felipe (Division de Ciencias Ambientales, Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la Presa San Jose 2055, Col. Lomas 4a secc. CP 78216, San Luis Potosi, SLP. Mexico)

      2010-01-15

      This study reports a fermentative hydrogen production by Escherichia coli using cheese whey as substrate. To improve the biohydrogen production, an E. coli {delta}hycA {delta}lacI strain (WDHL) was constructed. The absence of hycA and lacI genes had a positive effect on the biohydrogen production. The strain produced 22% more biohydrogen in a shorter time than the wild-type (WT) strain. A Box-Behnken experimental design was used to optimize pH, temperature and substrate concentration. The optimal initial conditions for biohydrogen production by WDHL strain were pH 7.5, 37 C and 20 g/L of cheese whey. The specific production rate was improved from 3.29 mL H{sub 2}/optical density at 600 nm (OD{sub 600nm}) unit-h produced by WDHL under non-optimal conditions to 5.88 mL H{sub 2}/OD{sub 600nm} unit-h under optimal conditions. Using optimal initial conditions, galactose can be metabolized by WDHL strain. The maximum yield obtained was 2.74 mol H{sub 2}/mol lactose consumed, which is comparable with the yield reached in other hydrogen production processes with Clostridium sp. or mixed cultures. (author)

    1. Contrôle des circuits auxiliaires des P.F.W. (arret machine 2004/2006)

      CERN Document Server

      Ottaviani, J

      2005-01-01

      Les PFW sont des nappes polaires installées sur les pôles des aimants du PS. Elles sont au nombre de 4 par unité d’aimant et constituées d’un circuit principal (dans lequel circule le courant désiré selon le cycle magnétique utilisé) et de circuits auxiliaires. Les circuits auxiliaires sont des enroulements de correction (boucles de tour et “pick-up” brasés sur les enroulements principaux). Pendant la variation du champ magnétique de l’aimant PS, on utilise des tensions induites dans ces circuits auxiliaires pour corriger les erreurs de champ dues aux pertes par courants de Foucault dans la chambre à vide. Chaque année, pendant l’arrêt machine, on vérifie si les caractéristiques des circuits auxiliaires correspondent aux normes (mesures des résistances des boucles de tours, résistances entre “pick-up” et isolation des circuits) afin de faire un suivi. Les 404 PFW sont ainsi vérifiées. Dans cette note, on ne relèvera que les PFW ayant des défauts (valeurs hors tolérances, ...

    2. Spiritual Content of Yoruba Concept of Sexuality and Sustenance of Family Values through Eko-Ile (Home Training)

      Science.gov (United States)

      Olaniyan, Gabriel O.

      2016-01-01

      This paper examined the spiritual content of the Yoruba concept of sexuality and the implications it has for the sustenance of family values by use of "eko ile" (home training) which parents are expected to provide for their children as they prepare them for good citizenship. It is observed that most complaints about bad behaviours of…

    3. Etat des lieux des soins de premier recours des malades mentaux à Antananarivo : étude rétrospective

      Science.gov (United States)

      Bakohariliva, Hasina Andrianarivony; Rafehivola, Imisanavalona Hanitrinihaja; Raobelle, Evah Norotiana; Raharivelo, Adeline; Rajaonarison, Bertille Hortense

      2018-01-01

      Résumé Religion et guérisseurs traditionnels occupent encore une place prépondérante dans la prise en charge des maladies mentales à Madagascar. Ainsi, nous nous sommes fixés comme objectif d'établir un état des lieux sur les soins de premier recours des malades mentaux. Nous avons mené une étude rétrospective descriptive s'étalant sur une période de 16 mois allant de janvier 2014 en avril 2015 au sein du service de psychiatrie du CHU de Befelatanana à Antananarivo. La prévalence des psychoses était de 25%. Le genre féminin (53%), l'ethnie merina (77%), les étudiants (45%), le niveau d'étude secondaire (40%), les célibataires (72%), la religion protestante (45%), ainsi que le niveau socio-économique moyen (57,5%) étaient prédominants. Dans les paramètres cliniques, le mode de début brutal (52%), le premier recours à la religion (40%), la présence d'antécédents des cas similaire (90%), étaient majoritaires. La schizophrénie était la pathologie la plus rencontrée dans la moitié des cas. Le délai d'amélioration en cas de traitement religieux et traditionnels était dans la moitié des cas de plus de 10 jours d'hospitalisation. Les patients ayant reçu une prise en charge psychiatrique en premier recours, étaient améliorés dans 75 % cas en moins de 10jours. Le retard du recours aux soins psychiatriques est une réalité à Madagascar qui aggrave le pronostic des psychoses. PMID:29632623

    4. Les besoins en isoleucine, valine et leucine chez le porcelet entre 7 et 15 kg

      DEFF Research Database (Denmark)

      Assadi Soumeh, Elham; van Milgen, Jaap; Sloth, Niels Morten

      2015-01-01

      croissance s’ils sont fournis en deçà du besoin. Des études de métaanalyse révèlent que peu de données de type dose‐réponse sont disponibles chez le porcelet pour l’Ile, notamment avec des aliments exempts de cellules de sang, et la Val (van Milgen et al., 2012, 2013). Par ailleurs, une revue de la...

    5. Accès à l'eau : des solutions techniques et sociales aident des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Grâce à la modélisation par ordinateur faisant appel à des techniques de pointe et à la consultation des collectivités, l'organisme bolivien Agua Sustentable a trouvé des solutions politiques à des conflits qui auraient pu s'avérer désastreux au sujet de l'accès à l'eau. Cet organisme de recherche subventionné par le CRDI a ...

    6. Le Débat des semences

      International Development Research Centre (IDRC) Digital Library (Canada)

      Solutions pour les lois nationales régissant le contrôle des ressources génétiques et des ...... des pouvoirs) qui reconnaissent, dans une certaine mesure, les droits de gestion collectifs des ...... documentés, les performances physiques, etc.

    7. 78 FR 3911 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive...

      Science.gov (United States)

      2013-01-17

      ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N259; FXRS1265030000-134-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive... significant impact (FONSI) for the environmental assessment (EA) for Big Stone National Wildlife Refuge...

    8. Deposition mechanism and microstructure of laser-assisted cold-sprayed (LACS) Al-12 wt.%Si coatings: effects of laser power

      CSIR Research Space (South Africa)

      Olakanmi, EO

      2013-06-01

      Full Text Available at the substrate and build up a coating. To circumvent the processing problems associated with cold-spray (CS) deposition of low-temperature, corrosion-resistant Al-12 wt.%Si coatings, a preliminary investigation detailing the effect of laser power on its LACS...

    9. The diluvial rains of Saguenay-Lac-Saint-Jean : status one year after

      International Nuclear Information System (INIS)

      Henri, N.; Beauchemin, G.; Alonso, M.; Gelinas, M.

      1997-01-01

      The status of damages and reconstruction in the Saguenay-Lac-Saint-Jean region, one year after the catastrophic torrential rain storm of July 1996 was presented. Numerous detailed maps and photographs of the principal washed-out, destroyed and damaged regions were presented, along with maps and photographs of the same areas after reconstruction, repair and landscaping. The maps show the different river beds, urban, and rural districts that were subjected to the catastrophic washouts, landslides and soil collapses. The report also includes a summary of the repair costs by municipal regions and the financial aid received by the region to help in the reconstruction effort. tabs., figs

    10. Performances de ponte et qualité des oeufs des poules pondeuses ...

      African Journals Online (AJOL)

      Les performances de ponte et la qualité des oeufs de 216 poules pondeuses ISA Brown âgées de 21 semaines ont été déterminées en les alimentant avec des rations contenant des feuilles séchées de manioc (Manihot esculenta, Crantz). Pendant douze semaines, trois groupes de 72 poules chacun (réparties en trois ...

    11. Freins et leviers à la diversification des cultures : étude au niveau des exploitations agricoles et des filières

      Directory of Open Access Journals (Sweden)

      Meynard Jean-Marc

      2013-07-01

      Full Text Available La diversification des cultures est souvent présentée comme un levier d’action pour accroître la durabilité des systèmes de production agricoles. Bien raisonnée, elle favorise en effet une réduction de l’usage d’intrants extérieurs à l’exploitation – pesticides, engrais, eau – et des nuisances environnementales associées à leur utilisation excessive. À l’inverse, la simplification des systèmes de culture engagée depuis plus de 40 ans s’est accompagnée d’un recours croissant aux intrants. Cependant, malgré son intérêt pour les systèmes de production en termes de durabilité écologique mais aussi économique (répartition des risques, et son inscription dans divers plans et dispositifs incitatifs, la diversification des cultures progresse peu. Les ministères en charge de l’agriculture et de l’environnement ont donc commandé à l’INRA une étude visant à identifier les freins à la diversification des cultures en France et les leviers mobilisables, par les pouvoirs publics notamment, pour la favoriser. L’hypothèse de travail est que ces freins relèvent du fonctionnement global du système agro-industriel, et de la capacité de développement de filières valorisant les cultures de diversification. L’étude a examiné un certain nombre de cas représentatifs de la diversité des filières et notamment de leurs modes d’organisation, qui déterminent la coordination et l’engagement des acteurs économiques impliqués dans le développement d’une culture de diversification.

    12. Impact écotoxicologique de mélanges de pesticides sur des fonctions microbiennes des sols : apport d’une prise en compte écologique dans l’évaluation des risques

      OpenAIRE

      Devers-Lamrani, Marion; Rouard, Nadine; Cheviron, Nathalie; Grondin, Virginie; Martin-Laurent, Fabrice

      2015-01-01

      L’utilisation de pesticides permet d’assurer la qualité de la production végétale mais elle contribue à la contamination des sols et des eaux et produit des effets sur des organismes noncibles. L’évaluation des risques requièrent actuellement une meilleure prise en compte des effets des pesticides sur le fonctionnement des écosystèmes. Or, les démarches et indicateurs classiques manquent de représentativité écologique. La fonction microbienne de biodégradation des pesticides est essentielle c...

    13. Mesure de la masse volumique des particules des eaux résiduaires urbaines : protocole et évaluation des incertitudes

      OpenAIRE

      RUBAN, Gwenaël; LABORATOIRE CENTRAL DES PONTS ET CHAUSSEES - LCPC

      2004-01-01

      La connaissance de la masse volumique des particules des eaux résiduaires urbaines est intéressante notamment pour l'étude de leur traitement par décantation ainsi que des relations entre concentrations en matières en suspension et paramètres optiques (turbidimétrie).Une étude des différentes méthodes de mesure de la masse volumique appliquées aux eaux résiduaires a été effectuée par G. Chebbo (1992). Il en a conclu que le pycnomètre à gaz type Beckman est le seul appareil donnant satisfactio...

    14. Problèmes entomologiques en replantation des palmeraies et des cocoteraies

      Directory of Open Access Journals (Sweden)

      Mariau Dominique

      2000-03-01

      Full Text Available C’est aux alentours de la vingt-cinquième année que l’on envisage de replanter une palmeraie. C’est en effet vers cet âge que commencent à se poser des problèmes de récolte en raison de la taille des palmiers. En un quart de siècle, l’amélioration génétique aura suffisamment fait de progrès pour escompter un gain de production de l’ordre de 20%. Enfin, dans certaines situations, plusieurs maladies ont pu affecter les vieilles palmeraies. Avec de 15 à 25% d’arbres manquants, principalement lorsque ceux-ci se présentent sous la forme de taches, une diminution de la production se fait nettement sentir. Cela peut, par exemple, être le cas avec les maladies de la fusariose en Afrique de l’Ouest, lorsque la palmeraie n’a pas été plantée avec du matériel végétal tolérant, ou du ganoderma en Malaisie. Le renouvellement des cocoteraies se fait avec un espace de temps beaucoup plus long. En effet, la récolte des noix peut se faire au sol et la hauteur des cocotiers n’est donc pas un facteur limitant. Par ailleurs, la majorité des cocoteraies étant sous la forme de petites plantations villageoises, les agriculteurs rechignent toujours à abattre leurs cocotiers, même si des semences potentiellement plus productives leurs sont proposées. Ce sont les raisons pour lesquelles les cocoteraies de 50 ans et plus représentent la règle. L’abattage d’une plantation de palmiers à huile ou de cocotiers constitue naturellement un changement brutal de l’environnement, ce qui a des conséquences importantes notamment sur l’entomofaune, parmi laquelle des ravageurs majeurs ainsi que leurs ennemis naturels.

    15. Innovation pour la santé des mères et des enfants d'Afrique

      International Development Research Centre (IDRC) Digital Library (Canada)

      Corey Piccioni

      ... détermineront les interventions devant absolument faire partie de la formation des travailleurs de santé communautaire. Cela pourrait comprendre des régimes de vitamines prénatals et des billets de transport à des établissements de santé pour le dépistage de troubles d'hypertension ou d'infection au VIH, entre autres.

    16. Isolement et identification des levures.

      Directory of Open Access Journals (Sweden)

      S. DOMERCQ

      1967-06-01

      Full Text Available La fermentation du moût de raisin est assurée par les levures qui se trouvent sur la pellicule du raisin, sur les rafles, et aussi, par celles qui envahissent le matériel de vendange et de vinification dès que la récolte est commencée. L'apparition deLa fermentation du moût de raisin est assurée par les levures qui se trouvent sur la pellicule du raisin, sur les rafles, et aussi, par celles qui envahissent le matériel de vendange et de vinification dès que la récolte est commencée. L'apparition des signes de la fermentation est spontanée. La fermentation est rapide dans la majorité des cas, si elle devient trop violente et que la température s'élève dangeureusement, il faut la « canaliser », la calmer. Des accidents peuvent se produire; des arrêts de fermentation laissant des sucres non fermentés pouvant être attaqués par d'autres microorganismes, des développements de levures formant des substances nuisibles à la qualité; par la suite, il s'agit d'obtenir la stabilité du vin, en particulier, éviter les refermentations des vins doux. L'étude de ces problèmes nécessite une étude préliminaire, celle des levures responsables de la fermentation alcoolique du jus de raisin, qui ne peut être faite que sur des cultures pures, isolées au préalable à l'aide de prélèvements soigneusement réalisés.s signes de la fermentation est spontanée. La fermentation est rapide dans la majorité des cas, si elle devient trop violente et que la température s'élève dangeureusement, il faut la « canaliser », la calmer. Des accidents peuvent se produire; des arrêts de fermentation laissant des sucres non fermentés pouvant être attaqués par d'autres microorganismes, des développements de levures formant des substances nuisibles à la qualité; par la suite, il s'agit d'obtenir la stabilité du vin, en particulier, éviter les refermentations des vins doux. L'étude de ces problèmes nécessite une étude pr

    17. Innovation pour la santé des mères et des enfants d'Afrique | CRDI ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      L'initiative Innovation pour la santé des mères et des enfants d'Afrique (ISMEA) cherche à améliorer la santé des mères, des nouveau-nés et des enfants en ... Cette initiative de 36 millions de dollars sur sept ans – financée conjointement par les Instituts de recherche en santé du Canada, Affaires mondiales Canada et le ...

    18. Mutagenicity of the peroxisome proliferators clofibrate, Wyeth 14,643 and di-2-ethylhexyl phthalate in the lacZ plasmid-based transgenic mouse mutation assay

      Directory of Open Access Journals (Sweden)

      Boerrigter Michaël

      2004-01-01

      Full Text Available Abstract Background Peroxisome proliferators are considered rodent carcinogens that are putative human non-carcinogens based on the presumed absence of direct genetic toxicity in rodent and human cells and the resistance of human cells to the induction of peroxisomes by peroxisome proliferators. The highly sensitive lacZ plasmid-based transgenic mouse mutation assay was employed to investigate the mutagenicity of several peroxisome proliferators based on several lines of evidence suggesting that these agents may in fact exert a genotoxic effect. Methods Male and female lacZ-plasmid based transgenic mice were treated at 4 months of age with 6 doses of 2,333 mg di-2-ethylhexyl phthalate (DHEP, 200 mg Wyeth-14,643, or 90 mg clofibrate per kg of bodyweight, respectively, over a two-week period. Control animals were treated with the respective vehicles only (35% propyl glycol for DEHP and Wyeth-14,643 treatment controls and sterile water for clofibrate treatment controls. The mutant frequency in liver, kidney and spleen DNA was determined as the proportion of retrieved mutant and wild-type lacZ plasmids expressed in Escherichia Coli C host cells employing a positive selection system for mutant plasmids. Results Exposure to DEHP or Wyeth-14,643 significantly increased the mutant frequency in liver, but not in kidney or spleen, of both female and male mice. Treatment with clofibrate did not lead to an increased mutant frequency in any of the organs studied. Conclusion The results indicate that some peroxisome proliferators display an organ-specific mutagenicity in lacZ plasmid-based transgenic mice consistent with historical observations of organ- and compound-specific carcinogenicity.

    19. Analyse des caractéristiques structurelles et des performances ...

      African Journals Online (AJOL)

      SARAH

      28 févr. 2014 ... performances technico-économiques de la riziculture irriguée en Côte d' .... en nous basant sur les prix des intrants et des produits en vigueur au cours ..... la recherche et de la vulgarisation et le transfert de technologies ; (2) ...

    20. Enquête de satisfaction des restaurants

      CERN Multimedia

      Staff Association

      2016-01-01

      Comité de surveillance des restaurants L’Association du personnel est représentée dans plusieurs comités dont le Comité de surveillance des restaurants (CSR) qui a pour mandat : de donner son avis sur toute question relative à la politique générale de l’Organisation en matière de restauration sur le site, y compris en ce qui concerne les termes et l’attribution des contrats d’exploitation des restaurants ; de définir dans le cadre des contrats d’exploitation des restaurants, les prestations correspondant aux besoins et, dans la mesure du possible, aux désirs du personnel ; de surveiller les prestations des restaurants, y compris en ce qui concerne la qualité et la préparation des produits ; de négocier avec les concessionnaires des restaurants au sujet des tarifs et de surveill...

    1. Contraintes d'adoption des technologies de gestion de la fertilite des ...

      African Journals Online (AJOL)

      La baisse de fertilité des sols, l'une des principales contraintes du secteur agricole au Togo, sévit encore plus dans la riziculture irriguée où les terres sont exploitées chaque année sans jachère. Face à cette situation, diverses solutions comme les technologies de gestion de la fertilité des sols ont été proposées.

    2. contraintes d'adoption des technologies de gestion de la fertilite des ...

      African Journals Online (AJOL)

      La baisse de fertilité des sols, l'une des principales contraintes du secteur agricole au Togo, sévit encore plus dans la riziculture irriguée où les terres sont exploitées chaque année sans jachère. Face à cette situation, diverses solutions comme les technologies de gestion de la fertilité des sols ont été proposées.

    3. Droit des organisations internationales

      CERN Document Server

      Sorel, Jean-Marc; Ndior, Valère

      2013-01-01

      Cet ouvrage collectif offre aux enseignants et chercheurs en droit international, aux praticiens et aux étudiants, une analyse actualisée du droit des organisations internationales. Il dresse en cinq parties un tableau, illustré par des exemples variés, des problématiques que soulève le phénomène polymorphe d institutionnalisation de la société internationale. La première partie est consacrée au phénomène des « organisations internationales », sous l angle à la fois de l institutionnalisation progressive des relations internationales et de la difficulté à cerner une catégorie unifiée. La deuxième partie rend compte de la création, de la disparition et des mutations des organisations internationales, ici envisagées comme systèmes institutionnels et ordres juridiques dérivés. La troisième partie analyse l autonomie que l acquisition de la personnalité juridique et de privilèges et immunités, un organe administratif intégré, un personnel ou un budget propres confèrent aux organi...

    4. Polarization burst in the BL Lac object AO 0235 + 164

      Energy Technology Data Exchange (ETDEWEB)

      Impey, C D; Brand, P W.J.L. [Edinburgh Univ. (UK). Dept. of Astronomy; Tapia, S [Steward Observatory, Tucson, AZ (USA)

      1982-01-01

      Simultaneous infrared and optical polarimetry and photometry have been obtained for AO 0235 + 164 covering a five night period. The object underwent a polarization burst during which the 2.2 ..mu..m polarization rose from 17.5 to 28.7 per cent and fell again to 14.9 per cent. At its peak the degree of optical polarization was 43.9 per cent, the highest linear polarization observed in a BL Lac object. The data show the degree of polarization to increase towards shorter wavelengths, and the effect is inconsistent with either dilution by a galactic component or simple one-component synchrotron models. The large changes in polarization are not accompanied by large changes in flux, a result which is difficult to explain using conventional models of these objects. Other implications of the luminosity, polarization and variability are discussed.

    5. De la problématique des articles synopsis dans la compilation des ...

      African Journals Online (AJOL)

      Autrement dit, au Gabon l'attention doit porter sur l'utilisation des articles synopsis dans la compilation des dictionnaires, en vue de refléter dans ses ouvrages la diversité linguistique et culturelle de ce pays. Ceci est d'autant plus vrai que l'utilisation des articles synopsis ne dépend aucunement de la typologie du ...

    6. Üniversite Öğrencilerinde Kimlik Gelişimi: Kimlik Statülerinin Sosyal Sermaye ve Kimlik Sermayesi ile Olan İlişkisi

      OpenAIRE

      Özdikmenli-Demir, Gözde

      2010-01-01

      Bu araştırmada, beliren yetişkinlik dönemindeki üniversite öğrencilerinin kimlik statüleri onların sosyal ve kimlik sermayeleri ile olan ilişkileri çerçevesinde incelenmiştir. Araştırmanın örneklemini Türkiye'nin altı farklı üniversitesinde okuyan toplam 985 (511 kız- 474 erkek) öğrenci oluşturmaktadır. Katılımcıların yaş ranjı 17.7 ile 27 arasında değişmekte olup yaş ortalaması 21.7'dir. A...

    7. Evaluation des pratiques de gestion des adventices en riziculture

      African Journals Online (AJOL)

      Les résultats ont montré que les méthodes de gestion de l'enherbement ont .... Le contrôle des adventices en riziculture irriguée a principalement .... mesurer la hauteur des plantes et la longueur ..... Performance agronomique du Sys- tème de ...

    8. DNA adducts, mutant frequencies and mutation spectra in λlacZ transgenic mice treated with N-nitrosodimethylamine

      NARCIS (Netherlands)

      Souliotis, V.L.; Delft, J.H.M. van; Steenwinkel, M.-J.S.T.; Baan, R.A.; Kyrtopoulos, S.A.

      1998-01-01

      Groups of λlacZ transgenic mice were treated i.p. with N-nitrosodimethylamine (NDMA) as single doses of 5 mg/kg or 10 mg/kg or as 10 daily doses of 1 mg/kg and changes in DNA N7- or O6-methylguanine or the repair enzyme O6-alkylguanine-DNA alkyltransferase (AGT) were followed for up to 14 days in

    9. Hopf Bifurcation and Delay-Induced Turing Instability in a Diffusive lac Operon Model

      Science.gov (United States)

      Cao, Xin; Song, Yongli; Zhang, Tonghua

      In this paper, we investigate the dynamics of a lac operon model with delayed feedback and diffusion effect. If the system is without delay or the delay is small, the positive equilibrium is stable so that there are no spatial patterns formed; while the time delay is large enough the equilibrium becomes unstable so that rich spatiotemporal dynamics may occur. We have found that time delay can not only incur temporal oscillations but also induce imbalance in space. With different initial values, the system may have different spatial patterns, for instance, spirals with one head, four heads, nine heads, and even microspirals.

    10. Contrôle des Circuits Auxiliaires des P.F.W. (arrêt machine 2003/2004)

      CERN Document Server

      Ottaviani, J

      2004-01-01

      Les PFW sont des nappes polaires installées sur les pôles des aimants du PS. Elles sont au nombre de 4 par unité d'aimant et constituées d'un circuit principal (dans lequel circule le courant désiré selon le cycle magnétique utilisé) et des circuits auxiliaires. Les circuits auxiliaires sont des enroulements de correction (boucles de tour et "pick-up" brasés sur les enroulements principaux). Pendant la variation du champ magnétique del'aimant PS, on utilise des tensions induites dans ces circuits auxiliaires pour corriger les erreurs de champ dues aux pertes par courants de Foucault dans la chambre à vide. Chaque année, pendant l'arrêt machine, on vérifie si les caractéristiques des circuits auxiliaires correspondent aux normes (mesures de résistances des boucles de tours, résistances entre "pick-up" et isolation des circuits) afin de faire un suivi. Les 404 PFW sont ainsi vérifiées. Dans cette note, on ne relèvera que les PFW ayant des défauts (valeurs hors tolérances, boucles ouvertes ...

    11. Performances des équipements utilisés en liaison froide en liaison froide en restauration hospitalière - Suivi des températures des entrées froides

      OpenAIRE

      Rosset , Philippe; Morelli , Elisabeth; Noël , Véronique; Poumeyrol , Gérard

      2007-01-01

      La restauration hospitalière présente un système de distribution des repas qui lui est spécifique : assemblage des denrées préparées et constitution des plateaux-repas dans un local dédié (dit d'allotissement) ; transport des plateaux-repas vers les unités de soins dans des enceintes mobiles permettant le maintien au froid des denrées consommées froides et la remise en température des aliments à consommer chauds. La présente étude concerne le suivi des températures de hors-d'œuvre dans trois ...

    12. ASCA and Contemporaneous Ground-based Observations of the BL Lacertae Objects 1749+096 and 2200+420 (BL Lac)

      International Nuclear Information System (INIS)

      Sambruna, R.M.; Ghisellini, G.; Hooper, E.; Kollgaard, R.I.; Pesce, J.E.; Urry, C.M.

      1999-01-01

      We present ASCA observations of the radio-selected BL Lacertae objects 1749+096 (z=0.32) and 2200+420 (BL Lac, z=0.069) performed in 1995 September and November, respectively. The ASCA spectra of both sources can be described as a first approximation by a power law with photon index Γ∼2. This is flatter than for most X-ray endash selected BL Lacs observed with ASCA, in agreement with the predictions of current blazar unification models. While 1749+096 exhibits tentative evidence for spectral flattening at low energies, a concave continuum is detected for 2200+420: the steep low-energy component is consistent with the high-energy tail of the synchrotron emission responsible for the longer wavelengths, while the harder tail at higher energies is the onset of the Compton component. The two BL Lacs were observed with ground-based telescopes from radio to TeV energies contemporaneously with ASCA. The spectral energy distributions are consistent with synchrotron self-Compton emission from a single homogeneous region shortward of the IR/optical wavelengths, with a second component in the radio domain related to a more extended emission region. For 2200+420, comparing the 1995 November state with the optical/GeV flare of 1997 July, we find that models requiring inverse Compton scattering of external photons provide a viable mechanism for the production of the highest (GeV) energies during the flare. In particular, an increase of the external radiation density and of the power injected in the jet can reproduce the flat γ-ray continuum observed in 1997 July. A directly testable prediction of this model is that the line luminosity in 2200+420 should vary shortly after (∼1 month) a nonthermal synchrotron flare. copyright copyright 1999. The American Astronomical Society

    13. Postmortem Kanda LC-MS MS ile Yasadışı Madde Taraması 62 Postmortem Adli Olguda Uygulanması

      Directory of Open Access Journals (Sweden)

      Serap Annette Akgür

      2007-04-01

      Full Text Available Biyolojik örneklerdeki yasadışı madde taraması adli olaylarda büyük bir öneme sahiptir. Kan veya plazma, madde derişim-leri ile bu maddelerin farmakolojik etkileri arasında iyi bir korelasyonun bulunması nedeniyle genellikle tercih edilen materyallerdir. Yasadışı madde analizinde, birçok laboratuar immunoassay yöntemleri ile tarama ve Gaz Kromatografi-Kütle Spektrometresi (GC-MS ile doğrulama şeklinde bir uygulama yapmaktadır. Bununla birlikte, sıvı kromatografi tekniklerinin gelişmesiyle birlikte Sıvı Kromatografisi-Kütle Spektrometresi (LC-MS ve tandem LC-MS (LC-MS/MS birleştirilmiş tekniklerinde özellikle polar ve ısıya dayanıksız olan maddelerin nitel ve nicel analiz amaçlı olarak kullanımı zamanla artmaktadır. Bu çalışmada, LC-ESI (Electrospray İonisation-MS/MS de morfin, (±-amfetamin, (+-metamfetamin, kokain, benzolekgonin, kokaetilen ve (--ll-nor-9-karboksi-t9-THC maddeleri taranmış ve tayin edilmiştir. Sonuç olarak, postmortem kanda uygulanabilecek, türevlendirme işlemine gerek duymayan, duyarlı ve seçimli olarak, çok düşük düzeylerdeki maddelerin doğru ve kesin olarak saptanmasını sağlayacak, LC-MS/MS yöntemi geliştirilmiş ve 62 postmortem adli olguya başarıyla uygulanmıştır. Anahtar kelimeler: Yasadışı madde, tarama, LC/MS/MS, postmortem kan

    14. Case series

      African Journals Online (AJOL)

      abp

      4 févr. 2015 ... Abstract. La drépanocytose est une maladie génétique à transmission autosomale codominante. Les patients homozygotes ont des crises hémolytiques qui génèrent les symptômes cliniques. Il s'agit d'une maladie fréquente. En France, la plupart des cas hospitalisés sont observés en Ile de France et.

    15. Vers une meilleure comprehension des savoirs disciplinaires et curriculaires des enseignants ou Ie paradigme retrouve

      Directory of Open Access Journals (Sweden)

      Stephane Martineau

      1999-01-01

      Full Text Available eet article se veut essentieUement un travail de synthese sous la forme d 'une breve revue de litterature au sujet des savoirs disciplinaires et curriculaires en enseignement. Plus specifiquement, il vise a determiner queUes sont les principales conclusions qui se degagent de la lecture des recherches empiriques sur les savoirs disciplinaires et curriculaires des enseignants des ordres d'enseignement primaire et secondaire. Il propose donc une classification des differentes dimensions constitutives du rapport entre les savoirs disciplinaires et curriculaires et la pratique enseignante. Les resultats mis au jour permettent d 'une part, d'identifier les facteurs qui entrainent des differences dans les connaissances disciplinaires et curriculaires des enseignants et d'autre part, de mieux saisir comment ces connaissances de l'enseignant peuvent influencer en retour sa pratique.

    16. Yüksek Hızlı Oksi Yakıt ile Üretilen WCCo-Mo Esaslı Kaplamaların Mikroyapı Karakterizasyonu

      Directory of Open Access Journals (Sweden)

      Serkan Islak

      2015-12-01

      Full Text Available Bu çalışma, yüksek hızlı oksi yakıt (HVOF ısıl püskürtme yöntemi ile SAE 4140 çeliği üzerinde üretilen WCCo-Mo kompozit kaplamaların mikroyapısal özelliklerini araştırmak için yapılmıştır. Bu amaç için WCCo tozlarına ilave edilen Mo miktarı % ağ. 10, 20, 30 ve 40 olarak değiştirilmiştir. Kaplamalar, faz bileşimi, mikroyapı ve sertlik özellikleri açısından karşılaştırılmıştır. Kaplama tabakalarının faz bileşimi ve mikroyapısı X-ışını difraktogramı (XRD ve taramalı elektron mikroskobu (SEM ile incelenmiştir. XRD sonuçları, WCCo-Mo kaplama tabakasının WC, W2C, Co3W3C, Mo2C, MoO2, Mo ve Co fazlardan oluştuğunu göstermiştir. Kaplamaların sertliği Mo artışı ile artmıştır.

    17. Contrôle hormonal des caractéristiques des fibres musculaires après la naissance

      OpenAIRE

      Cassar-Malek, Isabelle; Listrat, Anne; Picard, Brigitte

      1998-01-01

      Après la naissance, la croissance et les propriétés contractiles et métaboliques des fibres musculaires sont soumises à une régulation endocrinienne complexe. A l’exception des glucocorticoïdes, la plupart des hormones présente une action anabolique sur le tissu musculaire. Leur influence sur les caractéristiques des fibres est cependant très différente. Ainsi, les hormones somatotropes affectent peu la composition en fibres des muscles. La GH, comme l’IGF-1, régulerait cependant l’expression...

    18. Modélisation des propriétés diélectriques des nanocomposites ...

      African Journals Online (AJOL)

      Dans ce travail, nous nous intéressons aux propriétés diélectriques dans le domaine des micro-ondes (2.45, 9.50 et 35 GHz) des composites constitués des inclusions de noir de carbone dans une matrice résine époxyde. Nous avons utilisé deux types de carbone : le monarch 700 et le sterling, dont les diamètres des ...

    19. Civili, langue des Baloango

      DEFF Research Database (Denmark)

      Mavoungou, Paul Achille; Ndinga-Koumba-Binza, Hugues Steve

      , Congo, Angola, etc.) issus de la décolonisation. Il présente de façon succincte quelques phénomènes historiques, phonologiques, morphosyntaxiques, homonymiques et analogiques de la langue. Des faits sémantiques des emprunts linguistiques y sont également décrits dans le cadre des changements...

    20. Water in the Cratonic Mantle: Insights from FTIR Data on Lac De Gras Xenoliths (Slave Craton, Canada)

      Science.gov (United States)

      Peslier, Anne H.; Brandon, Alan D.; Schaffer, Lillian Aurora; O'Reilly, Suzanne Yvette; Griffin, William L.; Morris, Richard V.; Graff, Trevor G.; Agresti, David G.

      2014-01-01

      The mantle lithosphere beneath the cratonic part of continents is the deepest (> 200 km) and oldest (>2-3 Ga) on Earth, remaining a conundrum as to how these cratonic roots could have resisted delamination by asthenospheric convection over time. Water, or trace H incorporated in mineral defects, could be a key player in the evolution of continental lithosphere because it influences melting and rheology of the mantle. Mantle xenoliths from the Lac de Gras kimberlite in the Slave craton were analyzed by FTIR. The cratonic mantle beneath Lac de Gras is stratified with shallow (water contents extending to higher values than those from the shallow ones. The FTIR spectra of olivines from the shallow samples have more prominent Group II OH bands compared to the olivines from the deep samples, consistent with a more oxidized mantle environment. The range of olivine water content is similar to that observed in Kaapvaal craton peridotites at the same depths (129-184 km) but does not extend to as high values as those from Udachnaya (Siberian craton). The Slave, Kaapvaal and Siberian cratons will be compared in terms of water content distribution, controls and role in cratonic root longevity.

    1. Comment constituer et traiter des corpus issus des médias sociaux à l’aide des CAQDAS? NVivo : un instrument pour l’analyse des discours numériques

      Directory of Open Access Journals (Sweden)

      Ferrari Giovannipaolo

      2015-01-01

      Full Text Available Avec l’apparition des médias sociaux, le chercheur en Sciences Humaines et Sociales a vu s’ouvrir des possibilités de création de corpus à partir des données disponibles en ligne. Le risque dans ces modalités de création de corpus est de créer de grandes bases de données difficilement gérables avec les outils traditionnels et surtout dans le cadre d’une recherche qualitative. Pour cette raison, il semble important de mobiliser des outils numériques pour l’aide à la recherche. Ces logiciels sont appelés CAQDAS. Cette contribution montre comment les utiliser pour une enquête de terrain en ligne ou numérique afin d’organiser et d’analyser un corpus. Ce corpus est constitué en vue d’une analyse des discours produits dans le contexte professionnel de la radio utilisant les nouveaux médias.

    2. Ethnobotanique des plantes médicinales anti hémorroïdaires des ...

      African Journals Online (AJOL)

      SARAH

      2015-12-31

      Dec 31, 2015 ... but est de valoriser la médecine à base des plantes dans le traitement des pathologies ... médicinales anti hémorroïdaires et le coût réduit des recettes serait pour les populations démunies, ...... l'Afrique, Unesco/Aetfat/Unso.

    3. Table des illustrations

      OpenAIRE

      2016-01-01

      Tableaux Dates d’inauguration des grands hôtels japonais entre 1860 et 1945… 19 Histoire, tourisme et hôtellerie en Corée depuis les années 1870… 59-60 Dates d’inauguration des grands hôtels chinois depuis 1863… 84 Les hôtels de luxe et leurs capacités d’hébergement en Corée en 2000… 103 Les flux de personnes suscités par les hôtels « super luxe » de Séoul en 2000… 105 L’activité des grands hôtels à Séoul en 1999 (en wons)… 106 Propriété et gestion des grands hôtels à Séoul en 1999…. 110 La c...

    4. La recherche en action : des solutions locales, des effets durables ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      15 déc. 2010 ... Le Centre de recherches pour le développement international (CRDI) appuie la production et l'application de connaissances qui améliorent de façon notable la situation des habitants des pays en développement.

    5. La revolution des savants

      CERN Document Server

      Chavanne, A

      1989-01-01

      Premiere cassette : - 1666 : impact de la creation de l'Academie des Sciences par Colbert, trente ans apres le proces de Galile, et au moment des disparitions de Pascal, Descartes et Fermat. Elle dirigee par le hollandais Huyggens jusqu'a sa fuite de France au moment de la revocation de l'Edit de Nantes. - 1750 : l'Encyclopedie (ou "Dictionnaire raisonne des Sciences, des Arts et des Metiers") de Diderot et d'Alembert, soutenus par Malherbes, Buffon, Condorcet et Rousseau. - 1789 : Revolution francaise. - 8 aout 1793 : l'Assemblee, par une declaration de Marat, dissout l'Academie des Sciences. Celle-ci continue cependant ses travaux pour les poids et mesures jusqu'en 1795. - la Terreur : la condamnation a mort, pas au nom d'une "Revolution qui n'a pas besoin de savants" mais pour d'autres raisons, de trois grands hommes de science : Lavoisier, Bailly et Condorcet. - 1793-1794 : Au printemps 93, le Comite de Salut Publique s'inquiete du demi-million de soldats etrangers de toutes les pays frontaliers qui essai...

    6. p21-LacZ reporter mice reflect p53-dependent toxic insult

      International Nuclear Information System (INIS)

      Vasey, Douglas B.; Wolf, C. Roland; MacArtney, Thomas; Brown, Ken; Whitelaw, C. Bruce A.

      2008-01-01

      There is an urgent need to discover less toxic and more selective drugs to treat disease. The use of transgenic mice that report on toxic insult-induced transcription can provide a valuable tool in this regard. To exemplify this strategy, we have generated transgenic mice carrying a p21-LacZ transgene. Transgene activity reflected endogenous p21 gene activation in various tissues, displayed compound-specific spatial expression signatures in the brain and immune tissues and enabled p53-dependent and p53-independent responses to be identified. We discuss the application of these mice in delineating the molecular events in normal cellular growth and disease and for the evaluation of drug toxicity

    7. Diversification des moyens de subsistance des petits producteurs de ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      L'économie du Malawi repose essentiellement sur la culture du tabac, qui représente plus de 70 % des revenus d'exportation. Pour 60 % des 100 000 membres de la National Smallholder Farmers' Association of Malawi (NASFAM), le tabac est la seule et unique source de revenus. Les cultivateurs de tabac, au Malawi ...

    8. À l’aube des dieux

      Directory of Open Access Journals (Sweden)

      Pascal Semonsut

      2011-03-01

      Full Text Available De l’avis même des préhistoriens, la Préhistoire assiste à la naissance du sentiment religieux. Cette religion des origines, quelle image en ont les Français ? Telle est la question que cet article aborde à partir de l’étude des manuels scolaires et des œuvres de fiction (littérature, cinéma et bande dessinée de la seconde moitié du XXe siècle. Si l’enseignement et la fiction n’accordent pas la même place à ce thème, en revanche tous deux font des préhistoriques des polythéistes adorant le soleil, construisant des mégalithes et prenant le plus grand soin de leurs morts. Ce mélange d’obscurantisme et de vraie spiritualité n’a qu’un but : montrer que notre espèce ne pouvait être que victorieuse dans ce combat qu’est l’humanisation.

    9. La maison des mathématiques

      CERN Document Server

      Villani, Cédric; Moncorgé, Vincent

      2014-01-01

      Comment travaillent les mathématiciens ? C'est peut-être en se promenant dans les couloirs de la première des " maisons des mathématiques " de France, l'institut Henri Poincaré, que l'on trouvera quelques réponses. Le mathématicien Cédric Villani et le physicien Jean-Philippe Uzan nous invitent à découvrir cette discipline et ses acteurs. Au fil des pages on suit, à travers de superbes images signées du photographe Vincent Moncorgé, la façon dont se fabrique cette science qui reste souvent mystérieuse. Toutes les dimensions, scientifique, esthétique et poétique, des mathématiques sont convoquées grâce à des regards croisés : la diversité des inspirations des chercheurs, la source de leur créativité, l'imaginaire littéraire et artistique des mathématiques, la drôle de tribu des mathématiciens. Un voyage au cœur de cette " auberge espagnole " des mathématiques, campus " à la française " accueillant des centaines de chercheurs du monde entier, devenu un lieu d'émulation et d'éc...

    10. Modernisation des marchés agroalimentaires - inclusion des petits ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Les marchés agroalimentaires connaissent de rapides changements dans les pays en développement et les pays en transition. Sous l'influence de la libéralisation du commerce et des nouvelles technologies de transformation des aliments et de commerce de détail, les marchés agroalimentaires évoluent vers une plus ...

    11. Culture du bambou : diversification des moyens de subsistance des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Culture du bambou : diversification des moyens de subsistance des petits producteurs de tabac du sud de la province de Nyanza, au Kenya - phase II. Au cours de la première phase du projet (projet no 103765), les chercheurs ont effectué une analyse de marché pour le bambou et les produits du bambou, comparé les ...

    12. Structurations formelle et conceptuelle des articles de dictionnaires : le premier modèle de codification des articles dans l’histoire des dictionnaires Larousse

      Directory of Open Access Journals (Sweden)

      Corbin Pierre

      2014-07-01

      Nous nous proposons d’examiner, dans l’histoire des dictionnaires généraux monolingues Larousse des origines à nos jours, une sélection de jalons de l’articulation entre structure conceptuelle et structure formelle des articles. Au regard de l’ampleur des données à couvrir, il ne pourra bien entendu s’agir que d’un survol, mais celui-ci permettra (1 de présenter le premier des trois modèles majeurs de codification des articles dans l’histoire des dictionnaires Larousse, celui qui trouve son origine dans le Nouveau dictionnaire de la langue française de 1856 ou ses éditions révisées, (2 de prendre en compte les dictionnaires proposés par cet éditeur en un siècle et demi qui ont repris le modèle de 1856 ou sa forme révisée, et (3 de présenter contrastivement au premier les deux autres modèles majeurs, qui trouvent leur ancrage chronologique respectivement dans le Grand dictionnaire universel du XIXe siècle de 1866-1876 et le Dictionnaire du français contemporain de 1966.

    13. The ultraviolet to X-ray continua of BL Lac objects

      International Nuclear Information System (INIS)

      George, I.M.; Warwick, R.S.; McHardy, I.M.

      1988-01-01

      The results from EXOSAT observations of three X-ray bright BL Lacertae objects, Mrk 501, 1218 + 304 and Mrk 180 are presented. All three sources have soft power-law X-ray spectra with low-energy cut-offs consistent with absorption in the line-of-sight gas column density through our own galaxy. The three objects also exhibit significant spectral variability in the X-ray band on time-scales ranging from a few days to a year. In each case, X-ray flux and spectral index appear to be correlated, in the sense that the X-ray spectrum hardens as the source brightens. The intrinsic ultraviolet to X-ray spectrum of these and several other X-ray bright BL Lac objects can be modelled as a power-law continuum of energy index ∼1.0 below about 0.1 keV, above which the spectral slope steepens. (author)

    14. Etat des lieux de la gestion des insecticides au Togo, Afrique de l ...

      African Journals Online (AJOL)

      Pour parvenir à une gestion optimale des maladies à transmission vectorielle ou tout au moins la nuisance culicidienne, une surveillance permanente des facteurs de risque devient nécessaire. Le principal facteur de risque est le vecteur qui transmet la maladie, et le contrôle du vecteur passe par des stratégies de lutte qui ...

    15. Des Connaissances Aux Politiques

      International Development Research Centre (IDRC) Digital Library (Canada)

      Les synergies ont été mises en commun au fur et à mesure des progrès de la recherche. .... Recherche normative (sur le rôle et la performance des institutions .... Système national d'information sur la gestion environnementale connecté à 19 ...... Un fort contrôle centralisé sur l'élaboration des politiques nationales peut ...

    16. Rôle et limites des tiers-lieux dans la fabrique des villes contemporaines

      OpenAIRE

      Besson, Raphaël

      2017-01-01

      La notion de tiers-lieux se développe de manière essentiellement empirique. Elle recouvre des réalités multiples, comme des projets de coworking spaces, de living labs et de fab labs. Certains tiers-lieux s’intéressent tout particulièrement à la ville et aux nouvelles conditions de la fabrique urbaine. En s’appuyant sur des méthodes d’innovation ouverte et le potentiel des outils numériques, ces tiers-lieux défendent l’idée d’un urbanisme qui ne soit plus le patrimoine exclusif d’experts, mai...

    17. L'incidence du prix et des stratégies d'emballage des produits du ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Des données internationales, en provenance surtout des pays à revenu élevé, ... pour s'attaquer aux stratégies de marketing ciblant des groupes vulnérables dans ... Les conclusions d'un programme financé par le CRDI au premier plan de la ...

    18. Etat des lieux de la reproduction sexuée des ignames africaines ...

      African Journals Online (AJOL)

      Les ignames sont d'importantes plantes alimentaires à multiplication végétative dont l'amélioration et la création variétale dépendent, comme chez les végétaux, de la maîtrise de la biologie de la reproduction sexuée. L'état des lieux des cultivars florifères des ignames africaines Dioscorea cayenensis – D. rotundata a été ...

    19. La réforme des politiques sociales : Évolution des perspectives du ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Le XXe siècle est une époque remarquable sur le plan des progrès matériels et des transformations d'ordre social et politique. Partout dans le monde, les conditions de vie de la population ont profondément changé à bien des égards: le taux de mortalité infantile et l'analphabétisme chez les adultes ont diminué de façon ...

    20. Recueillir des données probantes à l'échelle des collectivités pour ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Ce projet contribue à la collecte, à l'échelle des collectivités, de données probantes sur les souvenirs des victimes de violations des droits de la personne. Il vise aussi à trouver des stratégies de reconstruction post-atrocités dans un cadre local sûr. Enfin, l'équipe a créé un site Web et produit plusieurs publications.

    1. Innova on pour la santé des mères et des enfants d'Afrique

      International Development Research Centre (IDRC) Digital Library (Canada)

      19 janv. 2018 ... Les conclusions révèlent des similitudes parmi les cas de divers contextes na onaux, fournissant une riche base de preuves afin d'inspirer des ini a ves visant à améliorer l'équité en ma ère de santé. OUVRIR LE PDF | COMMANDER LE LIVRE. Innova on pour la santé des mères et des enfants d'Afrique.

    2. Administration et gestion des contrats XL

      CERN Document Server

      Senouf, J

      2000-01-01

      Les grands contrats de travaux génèrent un grand nombre de commandes (OSVC) passées par un grand nombre de responsables techniques. Ils sont généralement basés sur des bordereaux de prix associés à un éventail de conditions économiques adaptées aux besoins complexes et variés des multiples utilisateurs du CERN nécessitant des calculs sophistiqués. L'administration des commandes, le suivi des travaux et de la facturation doivent répondre aux besoins de tous les acteurs. Les responsables techniques doivent jouir de la plus large indépendance administrative dans le respect des règlements CERN et des conditions contractuelles. Le contrôle des métrés et décomptes doit être rigoureux et d'une traçabilité complète. L'utilisation des bases de données Oracle a déjà permis l'intégration des données administratives et techniques. Le Web nous invite à une communication totale et transparente entre les utilisateurs, les services techniques et les contractants. De nouveaux types de contrat so...

    3. Approche historique des classifications en psychiatrie

      OpenAIRE

      Garrabé , J.

      2011-01-01

      Resume Des le milieu du xixe siecle s?est posee la question des criteres de classification des maladies. Pour les maladies mentales, diverses classifications ont alors ete proposees par des auteurs francais (Morel) et allemands (Kahlbaum, Kraepelin). A partir de la fin du xixe siecle, le Bureau International de Statistique (Paris) a publie a une Classification Internationale des Maladies, a revision decennale (J. Bertillon). Cette tache a ete poursuivie dans l?entre-deux-guerres pa...

    4. Étude sur la nutrition menée dans des écoles de la Grenade - des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Étude sur la nutrition menée dans des écoles de la Grenade - des données probantes pour éclairer les politiques. Prévention des maladies non transmissibles. (PMNT). PROFIL DE PROJET. Le programme Prévention des maladies non transmissi- bles (PMNT) soutient la production de nouvelles connais- sances en vue ...

    5. Largemouth bass (Micropterus salmoides Lacépède): reproduction management and larval rearing in Italy

      OpenAIRE

      A. Dees; P. Melotti; R. Vicenzi; A. Roncarati

      2010-01-01

      Micropterus salmoides (Lacépède) was originally present into the waters of the eastern United States of America, northern Mexico and southern Canada. This species can be distinguished from the other black basses by the fact that its mouth extends to and beyond the edge of the eye and the first and the second dorsal fins are almost separated by a deep dip and there are no scales on the soft rayed of the second dorsal fin.

    6. Les effets des interfaces sur les proprietes magnetiques et de transport des multicouches nickel/iron et cobalt/silver

      Science.gov (United States)

      Veres, Teodor

      Cette these est consacree a l'etude de l'evolution structurale des proprietes magnetiques et de transport des multicouches Ni/Fe et nanostructures a base de Co et de l'Ag. Dans une premiere partie, essentiellement bibliographique, nous introduisons quelques concepts de base relies aux proprietes magnetiques et de transport des multicouches metalliques. Ensuite, nous presentons une breve description des methodes d'analyse des resultats. La deuxieme partie est consacree a l'etude des proprietes magnetiques et de transport des multicouches ferromagnetiques/ferromagnetiques Ni/Fe. Nous montrerons qu'une interpretation coherente de ces proprietes necessite la prise en consideration des effets des interfaces. Nous nous attacherons a mettre en evidence, a evaluer et a etudier les effets de ces interfaces ainsi que leur evolution, et ce, suite a des traitements thermiques tel que le depot a temperature elevee et l'irradiation ionique. Les analyses correlees de la structure et de la magnetoresistance nous permettront d'emettre des conclusions sur l'influence des couches tampons entre l'interface et le substrat ainsi qu'entre les couches elles-memes sur le comportement magnetique des couches F/F. La troisieme partie est consacree aux systemes a Magneto-Resistance Geante (MRG) a base de Co et Ag. Nous allons etudier l'evolution de la microstructure suite a l'irradiation avec des ions Si+ ayant une energie de 1 MeV, ainsi que les effets de ces changements sur le comportement magnetique. Cette partie debutera par l'analyse des proprietes d'une multicouche hybride, intermediaire entre les multicouches et les materiaux granulaires. Nous analyserons a l'aide des mesures de diffraction, de relaxation superparamagnetique et de magnetoresistance, les evolutions structurales produites par l'irradiation ionique. Nous etablirons des modeles qui nous aideront a interpreter les resultats pour une serie des multicouches qui couvrent un large eventail de differents comportements magnetiques

    7. Quasi-simultaneous observations of the BL Lac object MK 501 in X-ray, UV, visible, IR and radio frequencies

      Science.gov (United States)

      Kondo, D. M.; Worrall, D. M.; Mushotzky, R. F.; Hackney, R. L.; Hackney, K. H.; Oke, J. B.; Yee, H.; Neugebauer, G.; Matthews, K.; Feldman, P. A.

      1980-01-01

      Quasi-simultaneous observations of the BL Lacertae (Lac) objects MK 501 were performed for the first time at X-ray, ultraviolet, visible, infrared, and radio frequencies. The observed spectral slope from the X-ray to UV regions is positive and continuous, but that from the mid UV to visible light region becomes gradually flat and possibly turns down toward lower frequencies; the optical radio emission can not be accounted for by a single power law. Several theoretical models were considered for the emission mechanism. A quantitative comparison was performed with the synchrotron-self-Compton model; the total spectrum is found consistent with this model. The spectrum from visible light to X-ray is consistent with synchrotron radiation or with inverse-Compton scattering by a hot thermal cloud of electrons. The continuity of the spectral slope from X-ray to UV implied by the current data suggests that the previous estimates of the total luminosity of this BL Lac object is underestimated by a factor of about three or four.

    8. Lactose carrier protein of Escherichia coli. Structure and expression of plasmids carrying the Y gene of the lac operon.

      Science.gov (United States)

      Teather, R M; Bramhall, J; Riede, I; Wright, J K; Fürst, M; Aichele, G; Wilhelm, U; Overath, P

      1980-01-01

      The previously described hybrid plasmid pC7 which carries lacI+O+delta(Z)Y+A+ on a 12.3 X 10(6)-Mr DNA fragment [Teather et al. (1978) Mol. Gen. Genet. 159, 239-248] was partially digested with the restriction endonuclease EcoRI under conditions reducing the recognition sequence to d(A-A-T-T) and ligated to the vector pB322. lac Y-carrying inserts of various sized (Mr 1.5-4.7 X 10(6)) were obtained. Hybrid plasmid pTE18 (2300-base-pair insert) carries part of the I (repressor) gene, the promotor-operator region, part of the Z (beta-galactosidase) gene, the Y (lactose carrier) gene and part of the A (transacetylase) gene. Upon induction of pTE18-harbouring strains the Y-gene product is expressed at a nearly constant rate for several generations and accumulates to a level of 12-16% of the total cytoplasmic membrane protein. Integration into the membrane leads to active carrier as judged by binding and transport measurements.

    9. Les caractéristiques des stomates des feuilles de Ficus benjamina L ...

      African Journals Online (AJOL)

      SARAH

      25 mars 2014 ... gaz d'échappement des véhicules et des cheminés des usines (Barima et al., 2014). En outre, ces .... inférieures de celle-ci ont été nettoyées à l'eau distillée. Une partie de chaque face inférieure de la feuille a ..... réaction de la plante à empêcher l'absorption de polluants tout en optimisant l'absorption de ...

    10. Inventaire des cavités souterraines abandonnées et cartographie des dangers qui leur sont liés

      Directory of Open Access Journals (Sweden)

      Claire ARNAL

      1994-12-01

      Full Text Available Un inventaire national des cavités souterraines abandonnées, des accidents de sol qui leur sont imputables et de leurs conséquences dommageables a été réalisé à l’échelle de 1/1 000 000 en 1993 et 1994 par le BRGM pour le ministère de l’Environnement (Direction de la Prévention des Pollutions et des Risques. Il a conduit à élaborer des documents cartographiques de synthèse et à définir des niveaux de dangers dont la localisation permettra de lancer des études plus détaillées en vue d’assurer la sécurité des personnes et des biens

    11. Thermal cracking in Lac du Bonnet granite during slow heating to 205 degrees celsius

      International Nuclear Information System (INIS)

      Chernis, P.J.; Robertson, P.B.

      1993-09-01

      Acoustic emissions (AE) were recorded as drill core samples of Lac du Bonnet granite were slowly heated to between 66 and 205 degrees celsius to evaluate the effects of temperature on the properties of rock samples. Longitudinal and shear velocities of the samples were measured, and Young's moduli, shear moduli and Poisson's ratios were calculated. No significant AE activity was detected until temperatures reached approximately 73-80 degrees celsius. Above this 'threshold' temperature, calculated rock properties decreased, and at 205 degrees celsius calculated Young's modulus, shear modulus, and Poisson's ratio were reduced by 30, 26, and 29% respectively

    12. Evaluation des pratiques de gestion des adventices en riziculture ...

      African Journals Online (AJOL)

      Le riz est l'aliment principal pour la quasi-totalité des populations vivant en Côte d'Ivoire. Cependant, les adventices sont considérées comme la contrainte biologique la plus importante faisant obstacle à la production rizicole. L'objectif de cette étude menée en 2015 était d'évaluer différentes techniques de gestion des ...

    13. Cartographie des zones d'intervention des partenaires techniques et ...

      African Journals Online (AJOL)

      cartographier les zones d'intervention des partenaires techniques et financiers au Bénin. L'approche méthodologique utilisée a consisté à la recherche documentaire, à la collecte de données auprès des partenaires techniques et financiers et à l'analyse de ces données. Les résultats ont permis de constater que cent dix ...

    14. Neutron Dosimetry and Irradiation of Solids; Dosimetrie des neutrons et irradiation des solides

      Energy Technology Data Exchange (ETDEWEB)

      Perriot, G; Schmitt, A P [Commissariat a l' Energie Atomique. Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

      1962-07-01

      Results of work at C.E.A. from 1958 to 1960 are reviewed. The possibilities offered by classical dosimetry methods are discussed. The tests which led to the utilization, for fast neutron dosimetry, of resistivity variations induced in solid W by such neutrons are described. Experimental W irradiation results led to a definition of neutron efficiency which describes the relations between neutron energy and their effects on materials. Possibilities offered by detectors which make use of radiation damage and are sensitive to neutrons at keV energies were explored. In other work, the principal French reactors were classified according to their ability to produce damage in materials such as W. (authors) [French] Dans ce rapport on a presente les resultats essentiels de travaux qui ont ete effectues de 1958 a 1980 par des chercheurs du CEA issus de differents services. En meme temps qu'une revue des possibilites offertes a l'epoque par les methodes classiques de dosimetrie (utilisation des detecteurs par activation), on a decrit les essais qui devaient permettre d'utiliser, a la dosimetrie les neutrons rapides, les variations de resistivite qu'ils creent dans un corps solide (tungstene). L'irradiation du tungstene a montre l'importance qu'il y avait a definir 'l'efficacite' des neutrons, c'est-a-dire leur aptitude plus ou moins grande, selon leur energie, a creer des defauts dans les materiaux. L'efficacite d'un emplacement d'irradiation se trouvant liee au spectre neutronique, on a vu les difficultes qu'il y avait a utiliser les detecteurs par activation des qu'on n'avait plus affaire a un spectre en 1/E ou de fission et on a pu entrevoir les possibilites offertes par les detecteurs utilisant la creation des defauts qui repondent a tous les neutrons d'energies, superieures a quelques keV. Enfin, on a classe les principaux types de Piles Francaises selon leur aptitude a creer plus ou moins rapidement des dommages dans des materiaux comme le tungstene. (auteur)

    15. Biometrische Untersuchungen des Stylopodiums, Zygopodiums und Metapodiums pleistozäner Ursiden im Hinblick auf die Evolution des Höhlenbären und die Klassifizierung des Fundmaterials Einhornhöhle / Harz

      OpenAIRE

      Athen, Kerstin Anja

      2007-01-01

      In der vorliegenden Dissertation "Biometrische Untersuchungen des Stylopodiums, Zygopodiums und Metapodiums pleistozäner Ursiden im Hinblick auf die Evolution des Höhlenbären und die Klassifizierung des Fundmaterials Einhornhöhle / Harz" wurden Daten des oberpliozänen Ursus etruscus, des pleistozänen Ursus deningeri sowie des Ursus spelaeus ausgewertet. Zur Datenerhebung wurden 249 Messgrößen an den Skelettelementen Humerus, Ulna, Radius, Metacarpalia I-V, Femur, Tibia, Fibula und Metatarsali...

    16. GESTION DES RISQUES ET DES INCERTITUDES L'EMERGENCE D'UN CONTRÔLE DE GESTION " PAR EXCEPTION "

      OpenAIRE

      Wegmann , Grégory

      2003-01-01

      International audience; Le thème de la gestion des risques a été peu abordé en contrôle de gestion et le fonctionnement des outils traditionnels comme les budgets postulent une maîtrise des risques et des incertitudes. L'émergence de nouvelles approches en contrôle de gestion montre une évolution sur ce point.

    17. Fuel poverty pre-diagnosis. Challenges, methods and comparison between Ile-de-France and national tools

      International Nuclear Information System (INIS)

      Boitel, Marc; Ceron, Pascale; Faure, Elise; Collinet, Sophie; Guillemot, Celia; Erard, Timothee

      2016-01-01

      Many initiatives and tools have been developed for many years to identify and evaluate fuel poverty over a local, regional or national territory. The multiplicity of available tools leads to complex choice for a territory approach. Through this document, the Iddri Institute and the ARENE Agency provide communities with a recap of today's identified challenges and methods for fuel poverty characterization in a given territory. The document presents a comparative evaluation and some tool sheets for the available pre-diagnostic solutions in the Ile-de-France and national territories

    18. Analyse des systèmes de gestion des déchets par l’étude du mécanisme de répartition des déchets

      OpenAIRE

      Bergeron, Francis

      2015-01-01

      Le renforcement de l’usage concurrentiel des déchets nous amène à étudier les processus d’approvisionnement des filières de valorisation et d’élimination sous l’angle de la circulation des flux de déchets au sein d’un système de gestion des déchets. L’objectif du présent article de recherche est de concevoir un cadre théorique autour du concept de mécanisme de répartition des déchets qui désigne le processus de distribution des flux de déchets entre les filières d’élimination et de valorisati...

    19. Questions de mathématiques élémentaires à l'usage des candidats aux écoles du Gouvernement, des aspirants au baccalauréat ès sciences et des élèves des établissements d'enseignement secondaire

      CERN Document Server

      Vuibert, Henry

      1879-01-01

      Questions de mathématiques élémentaires à l'usage des candidats aux écoles du Gouvernement, des aspirants au baccalauréat ès sciences et des élèves des établissements d'enseignement secondaire

    20. Üniversite Öğrencilerinde Kimlik Gelişimi: Kimlik Statülerinin Sosyal Sermaye ve Kimlik Sermayesi ile Olan İlişkisi

      OpenAIRE

      Özdikmenli-Demir, Gözde

      2011-01-01

      Bu araştırmada, beliren yetişkinlik dönemindeki üniversite öğrencilerinin kimlik statüleri onların sosyal ve kimlik sermayeleri ile olan ilişkileri çerçevesinde incelenmiştir. Araştırmanın örneklemini Türkiye'nin altı farklı üniversitesinde okuyan toplam 985 (511 kız- 474 erkek) öğrenci oluşturmaktadır. Katılımcıların yaş ranjı 17.7 ile 27 arasında değişmekte olup yaş ortalaması 21.7'dir. Araştırmada, Çok Boyutlu Algılanan Sosyal De...

    1. Production and consumption of B group vitamins in situ.

      OpenAIRE

      Kurata, A

      1984-01-01

      Les variations des concentrations en thiamine, biotine et vitamine B12 dans l'eau des bouteilles immergées in situ pendant 6 heures dans le bassin nord du lac Biwa ont été suivies sur 30 heures. Les concentrations en vitamines varient de façon comparable durant les 6 heures d'immersion. Généralement les concentrations en thiamine, biotine et vitamine B12 présentent des taux élevés le matin et bas le soir, ceci dans les bouteilles immergées comme dans l'eau de mer environnante. Les concentrati...

    2. Contribution à l’identification des déterminants fondamentaux en évaluation des banques

      Directory of Open Access Journals (Sweden)

      Badr Habba

      2016-03-01

      Full Text Available Ce papier étudie l’influence des facteurs fondamentaux sur l’évaluation des banques. Dans un premier temps, nous avons sélectionné, sur la base d’une revue de la littérature, les caractéristiques fondamentales susceptibles d’influencer l’évaluation des banques. Ensuite, nous avons estimé un modèle économétrique mettant en relation la valeur des banques et six variables explicatives à l’aide de l’économétrie des données de panel. L’échantillon est constitué d’un panel de 82 banques cotées entre 2005 et 2013. Les résultats obtenus montrent qu’il existe une influence très significative de la qualité du portefeuille bancaire de crédits, du niveau de capitalisation, du niveau de diversification du portefeuille d’activités, de l’efficience et de la taille de la banque sur l’évaluation des firmes bancaires.

    3. Impacts des caractéristiques physico-chimiques des eaux sur la ...

      African Journals Online (AJOL)

      Impacts des caractéristiques physico-chimiques des eaux sur la distribution du ... chimiques qui sont à l'origine d'une dégradation croissante de la qualité d'eau. ... Les valeurs d'indice de diversité de Shannon Weaver traduisent une grande ...

    4. Structure Demographique D'un Labeo Africain, Labeo coubie ...

      African Journals Online (AJOL)

      La taille moyenne des spécimens collectés en amont du lac (206,18 ± 63,55 mm LS) a été significativement plus importante (p<0,05) que celle des individus obtenus en aval (179,94 ± 56,66 mm LS). De même, la taille moyenne enregistrée pendant les mois de crue (285,28 ± 34,69 mm LS) a été largement supérieure à ...

    5. ETUDE EXPLORATOIRE DES ACIDES GRAS POLYINSATURÉS DES AIGUILLES DE PIN

      OpenAIRE

      KADARI, Abdelhamid

      2012-01-01

      Depuis les temps les plus anciens, l’utilisation des plantes dans le domaine de la santé est toujours d’actualité (1), dans la mesure où elle représente une alternative sérieuse ou tout au moins un complément appréciable à la pharmacie classique issue de la chimie moderne. En effet, plus de 25 % des médicaments prescrits dans le monde entier dérivent directement ou indirectement des plantes (2). Cependant, en tant que sources de médicaments, les plantes restent encore sous plusieurs études, s...

    6. Analyse des mécanismes de transmission des infections sexuellement transmissibles

      OpenAIRE

      Abraham, Shahnaz

      2008-01-01

      Ce travail comprend une étude de l'épidémiologie des infections sexuellement transmissibles (IST) et du VIH à Genève et en Suisse. Nous constatons une recrudescence des IST pendant la période analysée 1999-2004, supersosable à la situation observée dans les autres métropoles européennes, tandis que l'incidence du VIH est restée stable. Nous analysons les facteurs importants pour la transmission des IST-VIH et soulignons l'importance de poursuivre les campagnes de prévention, visant non seulem...

    7. Épuration des eaux usées des villes pour soutenir l'agriculture ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      2 févr. 2011 ... Les eaux usées : manne liquide ? ... Les racines de la plante emprisonnent les matières solides en ... le compostage des déchets ménagers ou l'arrosage des pépinières. ... à la gestion locale de la demande », dans Épuration des eaux usées et l'agriculture urbaine, Editions Enda, Dakar, août 2002. Mbodj ...

    8. Améliorer les conditions de vie des jeunes et des femmes en ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Améliorer les conditions de vie des jeunes et des femmes en développant la petite entreprise : mesure de l'impact. Durant les années 2000, la croissance économique et l'augmentation des investissements sociaux ont réduit la pauvreté et offert aux populations de l'Amérique latine de multiples débouchés sur le marché du ...

    9. VLBA Observations of Low Luminosity Flat Spectrum Radio Galaxies and BL Lac Objects: Polarisation Properties

      Science.gov (United States)

      Bondi, M.; Dallacasa, D.; Stanghellini, C.; Marchã, M. J. M.

      We obtained two-epoch VLBA observations at 5 GHz of a list of radio galaxies drawn from the 200 mJy sample (Marcha et al. 1996). The objects selected for milli-arcsecond scale observations are classified, on the basis of their optical spectroscopic and polarimetric properties, as BL Lac objects, normal weak line radio galaxies, broad line radio galaxies, and transition objects (those with intermediate properties). We present preliminary results on the radio polarization properties, on the milli-arcsecond scale, of objects with different optical properties and discuss structural variations detected from the two epochs.

    10. Tekstil boyar maddesinin sulu çözeltilerinden elektrokimyasal yöntemler ile giderimi

      OpenAIRE

      Yamaç, Duygu

      2016-01-01

      Bu çalışmada bir azo boya olan Deep Red içeren model atıksuyun arıtımı için mikroelektroliz, elektrokoagülasyon ve elektro-Fenton yöntemleri kullanıldı. Mikroelektroliz deneylerinde boya giderimi üzerinde dolgu maddesi, çözelti derişimi, pH, elektriksel iletkenlik ve besleme hızının etkileri incelenmiştir. Mikroelektroliz için en yüksek giderim olan %99,5 değerine toz demir talaşı-aktif karbon dolgu maddesi ile, 150 mg/L çözelti derişiminde, pH değeri 3, elektriksel iletkenlik ...

    11. Harmonische Reduktion des linken Ventrikels

      OpenAIRE

      Atila, M. (Mehmet)

      2005-01-01

      In der vorliegenden Arbeit wurde die harmonische Reduktion des linken Ventrikels am Modell des ausgewachsenen Hausschweins, unter Verwendung von Saugkappen variabler Größe untersucht. In 10 Schweinen mit Herzen normaler Größe und Funktion wurde eine Saugkappe, in Größe und Form an das abzufaltende Wandsegment angepasst, auf die epikardiale Oberfläche des schlagenden Herzens gesetzt. Wir führten Messungen der linksventrik. und der pulmonalart. Drücke, des ventrikulären Durchmessers und der Her...

    12. Étude des impacts écologiques du dynamisme spatio-temporel des ...

      African Journals Online (AJOL)

      transformer radicalement les occupations du sol. Toutefois, le recul des .... également de cette protection (Roberge et Angelstam 2004). L'objectif est de ... distribution des espèces cibles a ensuite été cartographiée sur la couche d'unités de ...

    13. Interplay of protein and DNA structure revealed in simulations of the lac operon.

      Directory of Open Access Journals (Sweden)

      Luke Czapla

      Full Text Available The E. coli Lac repressor is the classic textbook example of a protein that attaches to widely spaced sites along a genome and forces the intervening DNA into a loop. The short loops implicated in the regulation of the lac operon suggest the involvement of factors other than DNA and repressor in gene control. The molecular simulations presented here examine two likely structural contributions to the in-vivo looping of bacterial DNA: the distortions of the double helix introduced upon association of the highly abundant, nonspecific nucleoid protein HU and the large-scale deformations of the repressor detected in low-resolution experiments. The computations take account of the three-dimensional arrangements of nucleotides and amino acids found in crystal structures of DNA with the two proteins, the natural rest state and deformational properties of protein-free DNA, and the constraints on looping imposed by the conformation of the repressor and the orientation of bound DNA. The predicted looping propensities capture the complex, chain-length-dependent variation in repression efficacy extracted from gene expression studies and in vitro experiments and reveal unexpected chain-length-dependent variations in the uptake of HU, the deformation of repressor, and the folding of DNA. Both the opening of repressor and the presence of HU, at levels approximating those found in vivo, enhance the probability of loop formation. HU affects the global organization of the repressor and the opening of repressor influences the levels of HU binding to DNA. The length of the loop determines whether the DNA adopts antiparallel or parallel orientations on the repressor, whether the repressor is opened or closed, and how many HU molecules bind to the loop. The collective behavior of proteins and DNA is greater than the sum of the parts and hints of ways in which multiple proteins may coordinate the packaging and processing of genetic information.

    14. Interplay of protein and DNA structure revealed in simulations of the lac operon.

      Science.gov (United States)

      Czapla, Luke; Grosner, Michael A; Swigon, David; Olson, Wilma K

      2013-01-01

      The E. coli Lac repressor is the classic textbook example of a protein that attaches to widely spaced sites along a genome and forces the intervening DNA into a loop. The short loops implicated in the regulation of the lac operon suggest the involvement of factors other than DNA and repressor in gene control. The molecular simulations presented here examine two likely structural contributions to the in-vivo looping of bacterial DNA: the distortions of the double helix introduced upon association of the highly abundant, nonspecific nucleoid protein HU and the large-scale deformations of the repressor detected in low-resolution experiments. The computations take account of the three-dimensional arrangements of nucleotides and amino acids found in crystal structures of DNA with the two proteins, the natural rest state and deformational properties of protein-free DNA, and the constraints on looping imposed by the conformation of the repressor and the orientation of bound DNA. The predicted looping propensities capture the complex, chain-length-dependent variation in repression efficacy extracted from gene expression studies and in vitro experiments and reveal unexpected chain-length-dependent variations in the uptake of HU, the deformation of repressor, and the folding of DNA. Both the opening of repressor and the presence of HU, at levels approximating those found in vivo, enhance the probability of loop formation. HU affects the global organization of the repressor and the opening of repressor influences the levels of HU binding to DNA. The length of the loop determines whether the DNA adopts antiparallel or parallel orientations on the repressor, whether the repressor is opened or closed, and how many HU molecules bind to the loop. The collective behavior of proteins and DNA is greater than the sum of the parts and hints of ways in which multiple proteins may coordinate the packaging and processing of genetic information.

    15. Largemouth bass (Micropterus salmoides Lacépède: reproduction management and larval rearing in Italy

      Directory of Open Access Journals (Sweden)

      A. Dees

      2010-01-01

      Full Text Available Micropterus salmoides (Lacépède was originally present into the waters of the eastern United States of America, northern Mexico and southern Canada. This species can be distinguished from the other black basses by the fact that its mouth extends to and beyond the edge of the eye and the first and the second dorsal fins are almost separated by a deep dip and there are no scales on the soft rayed of the second dorsal fin.

    16. 50 Modélisation des propriétés diélectriques des nanocomposites ...

      African Journals Online (AJOL)

      AKA BOKO

      3 Laboratoire de Physique des Solides et des Couches Minces, Faculté des Sciences,. Sémlalia ... renfort (fibres de verre, carbone ou Kevlar,..) ont alors été utilisés ... diélectrique. Par ailleurs, pour modéliser le comportement diélectrique à la.

    17. Développer le leadership dans des villes de l'Amérique latine et des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      urbanisation rapide non planifiée, les villes des pays en développement sont à la fois le principal déclencheur des changements climatiques et le lieu approprié pour mettre en oeuvre des solutions. À l'heure actuelle, les villes de taille ...

    18. Charte du Conseil des Gouverneurs

      International Development Research Centre (IDRC) Digital Library (Canada)

      Office 2004 Test Drive User

      7. favoriser des communications ouvertes et franches entre le personnel, la direction ..... de dresser le procès-verbal des réunions du Conseil et de ses comités et de veiller à ce ... et des résultats qu'il obtient, et non de sa gestion quotidienne.

    19. Étude de la compétitivité de complexation des métaux issus des ...

      African Journals Online (AJOL)

      Les analyses chimiques effectuées sur le phosphate naturel révèlent la présence des métaux lourds. Pour étudier les risques de rétrogradation de ces engrais phosphatés, notre étude s'est portée sur la complexation des substances humiques naturelles extraites des sols sur des ions métalliques tels que le calcium, ...

    20. Utilisation des sous-produits agroalimentaires dans l’alimentation des poissons d’élevage en Côte d’Ivoire

      Directory of Open Access Journals (Sweden)

      Kimou Nestor B.

      2016-03-01

      Full Text Available Cette étude évalue l’impact de l’utilisation des sous-produits agroalimentaires dans l’alimentation des poissons d’élevage en Côte d’Ivoire. Une enquête a été réalisée en 2013 dans quinze principales zones piscicoles sur les caractéristiques technico-économiques des fermes, le profil socio-économique des promoteurs et les pratiques aquacoles, particulièrement l’alimentation des poissons. Les résultats révèlent que 71 % des pisciculteurs enquêtés utilisent des sous-produits agricoles durant au moins un stade de production. Parmi eux, 53 % utilisent exclusivement des sous-produits. Le son de riz (52 % et le mélange de sons de riz et de maïs (28 % sont les plus utilisés. Les prix moyens de ces sous-produits varient entre 20 et 105 FCFA/kg. Oreochromis niloticus et Heterotis niloticus sont les principales espèces élevées en polyculture sur les fermes. Les sous-produits sont utilisés en système semi-intensif, extensif et en rizipisciculture, en majorité en zone rurale. Les pisciculteurs sont pour la plupart des agriculteurs, âgés de plus de 40 ans. Les taux d’utilisation des sous-produits sont plus élevés dans les régions de l’Ouest, du Centre-Ouest et du Sud-Ouest de la Côte d’Ivoire, par rapport à celles du Sud et de l’Est. Les rendements des fermes sont relativement faibles (544 à 2445 kg/ha/an, avec des gains moyens quotidiens de 0,87 et 9,97 g/j pour le tilapia et l’heterotis respectivement. L’analyse des stratégies des acteurs suggère la nécessité de définir des mécanismes d’accompagnement et de financement de la pisciculture, afin que ces acteurs puissent améliorer les formulations alimentaires à partir des matières premières locales et accessibles.

    1. Gestion des déchets dangereux et responsabilité sociale des firmes

      Directory of Open Access Journals (Sweden)

      Faouzi Bensebaa

      2010-10-01

      Full Text Available Prenant les déchets électriques et électroniques comme terrain d’observation, cette recherche étudie les fondements du commerce illégal de déchets dangereux des pays développés vers les PED. En effet, malgré la multiplication des législations, le problème des déchets dans les pays développés, loin d’être traité en amont, l’est en grande partie en aval par leur délocalisation dans les PED. Les deux lectures proposées, économique et institutionnelle, permettent de montrer comment les contraintes de coût de gestion des déchets dans les pays développés conjuguées à l’imperfection et à la non-application des législations conduisent à des comportements socialement irresponsables. À partir de là, l’implication des parties prenantes est suggérée comme solution pour éliminer ce type de comportements.Based on the analysis of the waste electrical and electronic equipments (WEEE, the research investigates the motivations for the illegal cross-border trade in hazardous wastes from developed countries to developing countries. Although many developed countries have implemented waste shipment regulations, they are passing the risks and costs of E-waste to developing countries. Indeed, E-waste is often sent for recycling and refurbishing in developing countries. The two-side proposed approach (i.e. economical and institutional suggests that both the cost for firms to comply with increasing regulations and the imperfect implementation of regulatory restrictions lead to socially irresponsible behaviours. An increasing and better involvement of stakeholders may be put forward as a solution.

    2. L’impact de la participation bancaire dans le capital des entreprises sur la politique de distribution des dividendes

      Directory of Open Access Journals (Sweden)

      Naoel Mezgani

      2013-11-01

      Full Text Available L’objectif de ce papier est de tester l’incidence de la participation bancaire dans le capital des entreprises non financières sur la politique de distribution des dividendes. En utilisant des données de panel des trente entreprises tunisiennes durant la période de 1999 à 2004, nous vérifions si en détenant le capital et la dette, la banque a la possibilité de contraindre la distribution des dividendes pour garantir le remboursement de ses fonds prêtés. Les résultats empiriques obtenus ne confirment pas l’impact significatif des banques actionnaires majoritaires et principaux créditeurs sur la distribution des dividendes dans les entreprises tunisiennes. Ces dernières soutiennent surtout la stabilité du niveau des dividendes payés d’une année à une autre.

    3. Dégâts des bruches sur le pouvoir germinatif des graines de quatre ...

      African Journals Online (AJOL)

      SARAH

      29 févr. 2016 ... cultures vivrières de base en Afrique Occidentale et centrale (MULEBA et al., 1997). En RD Congo il est ... correspondant à deux cycles de reproduction, avec des trous ou des œufs sur elles. Les trous ... tout simplement de déterminer le nombre des bruches et leurs espèces à charger dans chaque boite ...

    4. autonomisation économique des femmes et économie du soin des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Alanna Karpa

      dépend en grande partie d'un financement versé par des bailleurs de fonds et qui est aux prises avec ... services dont leurs enfants ont besoin et à intégrer le marché du travail. ..... roulement, qui produit des services de soins de faible qualité.

    5. Digestibilidade e metabólitos sanguíneos de vacas da raça Holandesa superovuladas que receberam Lac100® ou linhaça em grão como fontes de gordura Digestibility and blood concentration of metabolites in superovulated dairy cows fed Lac100® or linseed as fat sources

      Directory of Open Access Journals (Sweden)

      F.L.B. Cavalieri

      2009-08-01

      Full Text Available Foram avaliados os efeitos de duas fontes de gordura, Lac100® (Yakult, fonte de ácido graxo ômega-6, e linhaça em grão (Linum usitatissimum (LIN, fonte de ácido graxo ômega-3, sobre a digestibilidade aparente da matéria seca (DMS, proteína bruta (DPB, fibra em detergente neutro (DFDN, fibra em detergente ácido (DFDA e extrato etéreo (DEE, e concentrações sanguíneas de HDL, LDL, VLDL, colesterol, triglicerídeos, glicose, cálcio, fósforo, N-ureico e progesterona. Foram utilizadas 10 vacas da raça Holandesa em lactação, distribuídas nos dois tratamentos, em um delineamento estatístico inteiramente casualizado. Os animais alimentados com Lac100® apresentaram maiores valores de DFDN (57,44% vs. 50,80% e DEE (77,70% vs. 72,18% quando comparados aos alimentados com LIN. Os animais alimentados com Lac100® apresentaram maiores concentrações de LDL (111,00 vs. 45,46mg/dL, HDL (82,27 vs. 64,93mg/dL e colesterol total (203,60 vs. 116,13mg/dL e menor concentração de N-ureico (13,22 vs. 15,19mg/dL em relação aos animais alimentados com linhaça em grão. As concentrações sanguíneas de glicose, cálcio, fósforo e progesterona não foram alteradas. Os resultados sugerem que a fonte de gordura na dieta modifica a DFDN e a DEE e, as concentrações sanguíneas de LDL, HDL e colesterol total em vacas em lactação.The effect of two sources of fat, calcium salts of soybean oil, Lac100® (Yakult, a source of omega-6 fatty acids or whole flaxseed (Linum usitatissiumum, a source of omega-3 fatty acids were evaluated to determine the apparent digestibility of dry matter (DDM, crude protein (DCP, neutral detergent fiber (DNDF, acid detergent fiber (DADF, and ether extract (DEE; and blood concentrations of HDL, LDL, VLDL, cholesterol, triglycerides, glucose, calcium, phosphorus, N-urea, and progesterone. Ten lactating Holstein cows were allocated in two treatments and a completely randomized design was used. Cows fed Lac100® had higher

    6. Les paysages périurbains montagnards à la croisée des regards des sciences écologiques et des sciences socio-économiques

      Directory of Open Access Journals (Sweden)

      Nathalie Bertrand

      2009-06-01

      Full Text Available Les mutations des paysages régionaux dues aux pressions urbaines questionnent l’usage du sol. Elles interpellent à la fois des enjeux économiques, sociaux et environnementaux voire spatiaux sous-tendus par l’étalement urbain, l’accroissement des déplacements domicile-travail, le mitage de l’espace. Ces évolutions et dysfonctionnements renvoient à la question de la durabilité du développement des régions, et particulièrement des Alpes, espace contraint géographiquement et objet de nombreuses pressions anthropiques et riche en biotopes remarquables. Cet article est basé sur deux ans de travaux menés par des socio-économistes et des écologues sur les effets sur le paysage et l’environnement de la périurbanisation d’un massif alpin. Nous avons pris en compte l’espace dans les processus environnementaux, économiques ou sociaux. Intrinsèque dans les analyses écologiques, elle a longtemps posé problème à l’économie pour intégrer l’espace comme dimension à part entière des processus économiques. Trois thèmes sont ici développés : l’approche du point de vue du paysage, les problèmes d’échelles spatiales et temporelles, le choix d’indicateurs. Ils demandent de hiérarchiser les questions et de pratiquer le travail en commun. Aller au-delà nécessite de développer une interrogation plus écologique ou plus économique et/ou sociale en quittant de ce fait l’interface pour favoriser des interrogations disciplinaires particulières.Changes in regional landscapes due to urban pressures raise questions regarding land use. They also give rise to economic, social and environmental issues related to urban sprawl, increases in daily commuting, and land consumption. These changes and dysfunctions are ultimately underpinned by the question of sustainable regional development. Mountain regions such as the Alps, with their various outstanding biotopes in a restricted space, are particularly vulnerable.

    7. ADAPTATION DES PRATIqUES D'ÉLEvAGE DES PRODUCTEURS ...

      African Journals Online (AJOL)

      1 Centre international de recherche développement sur l'élevage en zone subhumide (CIRDES). Unité de ... En saison des pluies, la taille élevée du cheptel des éleveurs ne leur permet pas l'accès aux bas-fonds (p <. 0,01). ..... animaux sont alors mis sur le marché pour faire .... modes de conduite alimentairedes animaux.

    8. Role of Thr399Ile and Asp299Gly polymorphisms of toll-like receptor-4 gene in acute dental abscess.

      Science.gov (United States)

      Miri-Moghaddam, Ebrahim; Farhad-Mollashahi, Narges; Baghaee, Elnaz; Bazi, Ali; Garme, Yasaman

      2017-02-01

      Apical Periodontitis (AP) is an inflammatory disease that affects the tissues surrounding the root end of a tooth. The disease which is caused by endodontic infections presents in different clinical ways including development of an acute abscess. Recent studies have provided information suggesting role of a multitude of factors in pathogenesis of acute apical abscess (AAA). In this case-control study, our goal was to evaluate the frequency and potential role of two common polymorphisms of toll like receptor-4 (TLR-4) gene; Thr399Ile (1196 C>T) and Asp299Gly (+896 A>G), in 50 patients with AAA as cases and 50 patients with asymptomatic apical periodontitis (AAP) as controls. Saliva sample containing mucosal epithelial cells was used for DNA extraction. Polymorphisms were detected by Tetra-ARMS (Amplification Refractory Mutation System) PCR method. Statistical analyses were carried out in SPSS 21 software. Homozygous wild type (CC) and heterozygous (CT) genotypes of Thr399Ile polymorphism were detected in 84% and 16% of AAA patients respectively. In controls, respective ratios were 94% (CC) and 6% (CT). Observed difference was not statistically significant ( P >0.05) for distribution of these genotypes. The mutant homozygous (TT) genotype of this polymorphism was identified in neither of the participants. Overall, T allele frequency was obtained 8% in AAA and 3% in AAP (OR=2.6, 95% CI; 0. 6-10.6, p >0.05). For Asp299Gly polymorphism, no individual was detected with the mutant allele in case or control groups. Our results indicated a possible role for Thr399Ile polymorphism in acute presentations of abscess in AAA. However, the impact of this polymorphism needs to be more assessed in future studies. Key words: Genetic polymorphism, periapical abscess, periapical periodontitis, toll-like receptor 4.

    9. Évaluation de la valeur nutritive et recherche des substances ...

      African Journals Online (AJOL)

      SARAH

      30 juin 2016 ... et des lipides. Puis, l'évaluation a été effectuée sur ces échantillons pour rechercher la présence des alcaloïdes, des saponines, des quinones, des stéroïdes, des terpenoïdes, des flavonoïdes, des leucoanthocyanes, des tannoïdes et des hétérosides cyanogénétiques. Les teneurs moyennes en humidité ...

    10. Complications du traitement traditionnel des fractures : aspects ...

      African Journals Online (AJOL)

      Tous les patients reçus avec des complications du traitement traditionnel des fractures ont été inclus dans ce travail. Le diagnostic des lésions était clinique et radiologique. Nous avions reçu 51 patients porteurs de complications suite à des traitements de médecine traditionnelle, soit 13,7% du total des patients hospitalisés ...

    11. Etude theorique et experimentale des evaporateurs de dioxyde de carbone operant dans des conditions de givrage

      Science.gov (United States)

      Bendaoud, Adlane Larbi

      Les evaporateurs de refrigeration sont surtout du type tube a ailettes, appeles serpentins, et fonctionnent dans l'une des conditions suivantes: seche, humide ou avec formation de givre. Il a ete demontre que la formation du givre sur la paroi exterieure de l'echangeur engendre une surconsommation energetique a cause des operations de degivrage puisque 15 a 20% seulement de la chaleur produite sert au degivrage tandis que le reste est dissipee dans l'environnement [1]. Avec l'avenement des nouveaux refrigerants, moins nocifs envers l'environnement, l'industrie du froid se trouve penalisee du fait que peu ou pas de composantes mecaniques (compresseur, pompe, echangeur...etc.) adaptees sont disponibles [3]. Il s'agit pour la communaute des frigoristes de combler ce retard technologique en redeveloppant ces composantes mecaniques afin qu'elles soient adaptees aux nouveaux refrigerants. Dans cette optique, et afin de mieux comprendre le comportement thermique des evaporateurs au CO2 fonctionnant dans des conditions seches, qu'un groupe de chercheurs du CanmetENERGIE avaient lance, en 2000, un programme de R & D. Dans le cadre de programme un outil de simulation des evaporateurs au CO2 a ete developpe et un banc d'essai contenant une boucle secondaire de refrigeration utilisant le CO2 comme refrigerant a ete construit. Comme continuite de ce travail de recherche, en 2006 ce meme groupe de recherche a lance un nouveau projet qui consiste a faire une etude theorique et experimentale des evaporateurs au CO2 operants dans des conditions de givrage. Et, c'est exactement dans le cadre de ce projet que se positionne ce travail de these. Ce travail de recherche a ete entrepris pour mieux comprendre le comportement thermique et hydrodynamique des serpentins fonctionnant dans des conditions de givrage, l'effet des circuits de refrigerant ainsi que celui des parametres geometriques et d'operation. Pour cela, un travail theorique supporte par une etude experimentale a ete effectue

    12. Multi-epoch intranight optical monitoring of eight radio-quiet BL Lac candidates

      Science.gov (United States)

      Kumar, P.; Gopal-Krishna; Stalin, C. S.; Chand, H.; Srianand, R.; Petitjean, P.

      2017-10-01

      For a new sample of eight weak-line quasars (WLQs) we report a sensitive search in 20 intranight monitoring sessions, for blazar-like optical flux variations on hour-like and longer time-scale (day/month/year-like). The sample consists exclusively of the WLQs that are not radio-loud and either have been classified as 'radio-weak probable BL Lac candidates' and/or are known to have exhibited at least one episode of large, blazar-like optical variability. Whereas only a hint of intranight variability is seen for two of these WLQs, J104833.5+620305.0 (z = 0.219) and J133219.6+622715.9 (z = 3.15), statistically significant internight variability at a few per cent level is detected for three of the sources, including the radio-intermediate WLQ J133219.6+622715.9 (z = 3.15) and the well-known bona fide radio-quiet WLQs J121221.5+534128.0 (z = 3.10) and WLQ J153259.9-003944.1 (z = 4.62). In the rest frame, this variability is intraday and in the far-ultraviolet band. On the time-scale of a decade, we find for three of the WLQs large brightness changes, amounting to 1.655 ± 0.009, 0.163 ± 0.010 and 0.144 ± 0.018 mag, for J104833.5+620305.0, J123743.1+630144.9 and J232428.4+144324.4, respectively. Whereas the latter two are confirmed radio-quiet WLQs, the extragalactic nature of J104833.5+620305.0 remains to be well established, thanks to the absence of any feature(s) in its available optical spectra. This study forms a part of our ongoing campaign of intranight optical monitoring of radio-quiet WLQs, in order to improve the understanding of this enigmatic class of active galactic nuclei and to look among them for a possible tiny, elusive population of radio-quiet BL Lacs.

    13. Piyasada Fermente Sucuk Olarak Satılan Ürünlerin Kalite Özelliklerinin Saptanması ve Geleneksel Türk Fermente Sucuğu ile Karşılaştırılması

      Directory of Open Access Journals (Sweden)

      Halime PEHLİVANOĞLU

      2015-07-01

      Full Text Available Bu çalışma, günümüz Türkiye’sinde marka olmuş firmalar tarafından üretilen ve fermente sucuk etiketi ile piyasaya sunulan sucukların karakteristik özelliklerinin araştırılması ve Geleneksel Türk Fermente Sucuk özellikleri ile karşılaştırılması amacı ile yapıldı. İstanbul piyasasında çeşitli markalarda satışa sunulan ve üzerinde fermente sucuk etiketi bulunan 30 adet sucuk numunesi çalışmada materyal olarak kullanıldı. Numunelerin tümünde Toplam Mezofil Aerob Mikroorganizmalar, Koliform Grubu Mikroorganizmalar, Laktik Asit Bakterileri, Stafilokok ve Mikrokoklar ile Küf ve Mayalar araştırıldı. Ayrıca pH değeri, rutubet miktarı, yağ miktarı, protein miktarı ve duyusal özellikleri incelendi. Elde edilen duyusal, fiziko-kimyasal ve mikrobiyolojik bulgulara göre, incelenen 30 adet sucuk numunesinin 8 adedinin (%26,6 fermente sucuk özelliğine yakın olduğu, 9 adedinin (%30,0 yarı fermente ve 13 adedinin (%43,3 ise ısıl işlem görmüş fermente olmayan sucuklar olduğu saptandı. Bu sonuçlara göre, fermente sucuk etiketi ile piyasaya sunulan ürünlerin 22 adedinin (%73,3 tam fermente olmaması nedeni ile ilgili yönetmelikler açısından taklit ve tağşiş kapsamına girdiği sonuç ve kanaatine varıldı.

    14. L'enrichissement des sols et des semences permet d'améliorer la ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      6 juin 2016 ... Grâce à des sols en meilleure santé et à l'utilisation de variétés améliorées, les agriculteurs du sud de l'Éthiopie ont multiplié par deux le rendement du pois chiche. L'amélioration des méthodes de transformation et de préparation de cet aliment, conjuguée à des programmes d'éducation, s'est traduite par ...

    15. EVALUATION DES POLITIQUES PUBLIQUES DE GESTION DES INONDATIONS AU JAPON - RAPPORT DE L'OCDE

      OpenAIRE

      Kovacs , Yves; Forestier , Ségolène; Lahidji , Ulf; Stevens , Barrie; Radisch , Jack; Schieb , Pierre-Alain

      2009-01-01

      18 p.; International audience; Méthodologie En coopération avec le gouvernement Japonais, le programme de l'OCDE sur l'avenir a entrepris en 2006 une évaluation de la politique Japonaise en matière de gestion des inondations. L'équipe sélectionnée par l'OCDE en charge de cette évaluation était composée d'experts indépendants. Suite à une étude préliminaire, l'équipe d'experts s'est déplacée au Japon pour interviewer des membres du gouvernement, des collectivités locales, des associations non ...

    16. Différences de sexe et rôle de l'internalisation des règles sur la propension des enfants à prendre des risques à vélo

      OpenAIRE

      GRANIE, Marie-Axelle

      2011-01-01

      L'objectif de cette étude est d'explorer les différences de sexe et l'effet de l'internalisation des règles routières sur la propension des enfants à prendre des risques à vélo. La perception du risque accidentel pour soi, l'internalisation des règles routières relatives aux comportements cyclistes et la propension à prendre des risques à vélo de 145 enfants (86 garçons et 59 filles) de 9 à 12 ans ont été mesurés par un autoquestionnaire. Les résultats montrent des différences de sexe sur l'i...

    17. The Radioisotopic Determination of Diffusion Coefficients and Currents in Natural Waters. Surface Collection of Radioactive Fall-Out on a Large Alpine Lake; Determination par detection nucleaire des coefficients de diffusion et des courants dans les eaux naturelles. Evolution de la surface de collection d'un grand lac alpin pour les retombees radioactives; Opredelenie koehffitsienta diffuzii i skorosti techeniya estestvennykh vod pri pomoshchi yadernogo detektirovaniya. Ehvolyutsiya poverkhnosti sbora radioaktivnykh osadkov na bol'shom al'pijskom ozere; Determinacion por deteccion nuclear de los coeficientes de difusion y de las corrientes en las aguas naturales evolucion de la superficie de captacion de un gran lago alpino para las precipitaciones radiactivas

      Energy Technology Data Exchange (ETDEWEB)

      Chesselet, R.; Nordemann, D. [Service d' Electronique Physique, Centre d' Etudes Nucleaires de Saclay (France); Dussart, B. [Centre de Recherches Hydrobiologiques, CNRS, Gif-sur-Yvette (France)

      1963-08-15

      'un coefficient de diffusion pour l'emetteur utilise et a la mesure eventuelle de la vitesse du courant au point ou la mesure est effectuee (dans le cas decrit, le lac Leman). Dans une seconde etape, en correlation avec une etude de geophysique concernant le probleme general des retombees radioactives, les auteurs ont utilise l'apport des retombees radioactives ayant pour origine les essais nucleaires atmospheriques (octobre 1961-janvier 1962). Des mesures de la radioactivite ont ete effectuees chaque jour sur des prelevements d'eau du lac Leman a des profondeurs de 0 m, 10 m, 20 m et sur un collecteur de retombees atmospheriques seches et humides. Malgre la complexite du regime des apports en fonction du temps, l'interpretation des diagrammes obtenus peut contribuer a resoudre le probleme du devenir des produits radioactifs dans les conditions de diffusion et de courants rencontrees. L'utilisation de la diffusion de produits radioactifs en tres faibles quantites et des differentes techniques de detection nucleaires a haute sensibilite actuellement disponibles peut conduire a une meilleure connaissance de la diffusion in situ et du mouvement des masses d'eaux naturelles. (author) [Spanish] En una primera etapa, los autores ha i provecado la difusion in situ de un emisor radiactivo, el sodio-22 en forma de Na{sup +}, de actividad muy baja (inferior al milicurie). La aplicacion de las leyes de la difusion a este caso facilita el calculo de la velocidad de difusion de la ''nube radiactiva''. Por consiguiente, el registro en funcion del tiempo de las actividades medidas con dos detectores gamma dispuestos de modo conveniente permite asignar un coeficiente de difusion ai emisor empleado y, eventualmente, evaluar la velocidad de la corriente en el punto en que se efectua la medicion (en el caso descrito, el lago Leman). En una segunda etapa, en relacion con un estudio geofisico del problema general de las precipitaciones radiactivas, los autores utilizaron la aportacion de las

    18. Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum.

      Science.gov (United States)

      Allen, Jeremy P; Hathway, Gareth J; Clarke, Neil J; Jowett, Mike I; Topps, Stephanie; Kendrick, Keith M; Humphrey, Patrick P A; Wilkinson, Lawrence S; Emson, Piers C

      2003-05-01

      The peptide somatostatin can modulate the functional output of the basal ganglia. The exact sites and mechanisms of this action, however, are poorly understood, and the physiological context in which somatostatin acts is unknown. Somatostatin acts as a neuromodulator via a family of five 7-transmembrane G protein-coupled receptors, SSTR1-5, one of which, SSTR2, is known to be functional in the striatum. We have investigated the role of SSTR2 in basal ganglia function using mice in which Sstr2 has been inactivated and replaced by the lacZ reporter gene. Analysis of Sstr2lacZ expression in the brain by beta-galactosidase histochemistry demonstrated a widespread pattern of expression. By comparison to previously published in situ hybridization and immunohistochemical data, Sstr2lacZ expression was shown to accurately recapitulate that of Sstr2 and thus provided a highly sensitive model to investigate cell-type-specific expression of Sstr2. In the striatum, Sstr2 expression was identified in medium spiny projection neurons restricted to the matrix compartment and in cholinergic interneurons. Sstr2 expression was not detected in any other nuclei of the basal ganglia except for a sparse number of nondopaminergic neurons in the substantia nigra. Microdialysis in the striatum showed Sstr2-null mice were selectively refractory to somatostatin-induced dopamine and glutamate release. In behavioural tests, Sstr2-null mice showed normal levels of locomotor activity and normal coordination in undemanding tasks. However, in beam-walking, a test of fine motor control, Sstr2-null mice were severely impaired. Together these data implicate an important neuromodulatory role for SSTR2 in the striatum.

    19. Mutagenesis of the lac promoter region in M13 mp10 phage DNA by 4'-hydroxymethyl-4,5',8-trimethylpsoralen

      International Nuclear Information System (INIS)

      Piette, J.; Decuyper-Debergh, D.; Gamper, H.

      1985-01-01

      Double-stranded M13 phage DNA (M13 mp10 replicative form) was photoreacted with 4'-hydroxymethyl-4,5',8-trimethylpsoralen, using light of wavelength greater than 320 nm or greater than 390 nm to generate predominantly crosslinks or monoadducts, respectively. The damaged DNAs were scored for inactivation and mutagenesis after transfection into Escherichia coli. The appearance of light-blue or colorless plaques on indicator medium showed that mutation had occurred in the lac insert of the viral DNA. A comparison of the consequences of the two phototreatments with psoralen supports the idea that crosslinks are both more lethal and more mutagenic than monoadducts. Numerous mutant clones partially or totally deficient in beta-galactosidase were plaque-purified and amplified. The viral DNA of each clone was sequenced by the dideoxy chain-terminating procedure. All of the observed base-pair changes were mapped to the lac promoter region and consisted of 3 transition, 14 transversion, and 6 single base-pair frame-shift mutations. The predominant mutation was a T.A----G.C transversion

    20. L’espace social des étudiants marocains dans la mobilité internationale. Spatialisation des réseaux et recomposition territoriale

      Directory of Open Access Journals (Sweden)

      Sabrina Marchandise

      2014-02-01

      Full Text Available La communication centre le propos sur l’étude des migrations étudiantes internationales, particulièrement marocaines. Ce thème se situe dans un contexte d’internationalisation de l’enseignement supérieur, au cœur des enjeux actuels qui ont trait à la mobilité des savoirs et des compétences et plus généralement dans les enjeux sociaux des réseaux. L’objectif général de la recherche réside dans la compréhension de la façon dont les étudiants marocains se représentent, conçoivent et produisent leurs rapports à l’espace, territorialisant de nombreuses aires. Comment alors penser les nouvelles formes de territorialité des étudiants marocains ? Les traductions spatiales des différents facteurs intervenant dans la dynamique sociale étudiante peuvent fournir des clés de lecture et d’interprétation des changements en cours (usages et technologies. Le projet consiste donc à saisir comment est structuré l’espace social des étudiants à travers les différents réseaux. Cet objectif pourra être atteint grâce à la spatialisation des réseaux étudiants marocains. Un croisement des méthodes et une articulation des échelles s’avèrent nécessaires pour une approche par les trajectoires et les pratiques des étudiants.

    1. Effets des electrons secondaires sur l'ADN

      Science.gov (United States)

      Boudaiffa, Badia

      Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire

    2. Analyse de la fiabilité des statistiques des pêcheries maritimes ...

      African Journals Online (AJOL)

      SARAH

      31 janv. 2016 ... SEDZRO Kossi Maxoe¹ *, FIOGBE Emile Didier¹, GUERRA Eduardo Balguerias², STAMATOPOULOS. Constantine³. ¹Laboratoire de Recherche sur les Zones Humides, Faculté des Sciences et des Techniques, Université d'Abomey-. Calavi, 01BP526 Cotonou Bénin, Tél. (229) 95268262. ²Institut Espagnol ...

    3. Original Paper Caractérisation et écologie des peuplements des ...

      African Journals Online (AJOL)

      Richard MAHAMBA BYANIKIRO1,2*, Jacob NDJAKI NSILA2,. Alidor KANKONDA BUSANGA2, Joseph ULYELALI-PATHO2,3 et. Jean-Claude MICHA4. 1Université de Goma, Faculté des Sciences Agronomiques,. Département de Phytotechnie, B.P : 204 Goma, R .D. Congo. ²Université de Kisangani, Faculté des Sciences,.

    4. Prise en charge des complications orbitaires et endocrâniennes des ...

      African Journals Online (AJOL)

      Le traitement du foyer sinusien est systématique aussi bien pour les complications orbitaires ou endocrâniennes si l'indication chirurgicale est retenue. Les complications orbitaires sont traitées par des antibiotiques visant les bactéries en cause avec des indications chirurgicales selon la classification scannographique de ...

    5. La qualité des plages au cœur des enjeux de développement : La situation des îles de l’océan Indien

      Directory of Open Access Journals (Sweden)

      Virginie Duvat

      2009-02-01

      Full Text Available La qualité des plages s’inscrit au cœur des enjeux de développement des petites îles tropicales en raison d’une part, de la place qu’elle occupe dans les stratégies de promotion touristique, et d’autre part, de l’importance que prend le littoral dans les pratiques récréatives et touristiques émergentes des populations locales. Dans ce contexte, l’objectif de cet article est de présenter les résultats d’une évaluation réalisée dans différentes îles des archipels des Seychelles et des Mascareignes, et de mettre en évidence la relation qui existe entre la qualité des plages, leurs attributs naturels et les politiques d’aménagement et de gestion des acteurs publics et privés.Today, the quality of the tropical beaches is closely linked to development challenges for two main reasons. At first, because sandy beaches play an important role in tourism development policies, and secondly because of the emergence of the touristic and recreative activities of the local communities. In this context, the purpose of this paper is to expose the results of an assessment which was done in the Seychelles and Mascarene islands and to highlight the relationship which can be observed between beach quality, natural assets and the strategies of public and private actors.

    6. Liste des auteurs

      OpenAIRE

      2016-01-01

      Madeleine Akrich      Ecole des Mines – Centre de Sociologie de l’innovation – Paris Noël Barbe      Association comtoise des Arts et Traditions populaires – Besançon Lucien Bernot      Ecole des hautes études en sciences sociales (EHESS) – Paris Anni Borzeix      Centre national de la recherche scientifique (CNRS) –     Groupement d’intérêt public (GIP) « Mutations industrielles » – Paris François Boudarias      Laboratoire d’Anthropologie et de sociologie de Tours (LAST) Dominique Boullier ...

    7. Les TIC au coeur des pédagogies universitaires diversité des enjeux pédagogiques et administratifs

      CERN Document Server

      Karsenti, Thierry

      2001-01-01

      Cet ouvrage illustre en quoi les TIC jouent un rôle si important en pédagogie universitaire et pourquoi ce virage technologique est devenu incontournable. Les auteurs font une place tant aux expériences qu'aux théories sur l'intégration des TIC. Il est question de la diversité des formes de recours aux TIC, des enjeux de leur intégration en milieu universitaire, des défis sociaux sous-jacents à cette incursion technologique, des cours sur le Web, de l'apprentissage collaboratif, de la supervision des stagiaires et de la réforme scolaire.

    8. Spectroscopy of 10 γ -Ray BL Lac Objects at High Redshift

      Energy Technology Data Exchange (ETDEWEB)

      Paiano, Simona; Falomo, Renato [INAF, Osservatorio Astronomico di Padova, Vicolo dell’Osservatorio 5, I-35122 Padova (Italy); Landoni, Marco [INAF, Osservatorio Astronomico di Brera, Via E. Bianchi 46, I-23807 Merate (Italy); Treves, Aldo [Università degli Studi dell’Insubria, Via Valleggio 11, I-22100 Como (Italy); Scarpa, Riccardo [Instituto de Astrofisica de Canarias, C/O Via Lactea, s/n E-38205 La Laguna, Tenerife (Spain)

      2017-08-01

      We present optical spectra with high signal-to-noise ratio of 10 BL Lac objects detected at GeV energies by the Fermi satellite (3FGL catalog), which previous observations suggested are at relatively high redshift. The new observations, obtained at the 10 m Gran Telescopio Canarias, allowed us to find the redshift for J0814.5+2943 ( z = 0.703), and we can set a spectroscopic lower limit for J0008.0+4713 ( z > 1.659) and J1107.7+0222 ( z > 1.0735) on the basis of Mg ii intervening absorption features. In addition we confirm the redshifts for J0505.5+0416 ( z = 0.423) and J1450+5200 ( z > 2.470). Finally we contradict the previous z estimates for five objects (J0049.7+0237, J0243.5+7119, J0802.0+1005, J1109.4+2411, and J2116.1+3339).

    9. L'analyse des corpus multimodaux en ligne : état des lieux et perspectives

      Directory of Open Access Journals (Sweden)

      Develotte Christine

      2012-07-01

      Full Text Available Partant de l’ouvrage "Texte et ordinateur. L’écriture réinventée ?" de Jacques Anis (1998 nous cherchons à montrer la trajectoire des travaux français en sciences du langage sur les corpus médiés par la technologie jusqu’à aujourd’hui. La communication en ligne renvoie à des formes diverses selon qu’il s’agit de la production de textes fixes (par exemple, sites Web, courriels ou de formes plutôt centrées sur les processus d’interaction et de communication (par exemple, chat, visioconférence susceptibles donc d’être étudiées tant du point de vue de l’analyse du discours que de celui de l’analyse conversationnelle. Nous nous proposons de montrer, dans cet article, dans quelle mesure les deux traditions en sciences du langage ont trouvé matière à exploiter ces corpus en ligne en empiétant, parfois, l’une comme l’autre, sur leurs « territoires » respectifs. Dans cette perspective, nous commençons par mettre au jour l’apport des chercheurs revendiquant leur appartenance à l’analyse du discours, puis celui des chercheurs relevant de l’analyse des interactions et nous montrons les zones de tuilage entre les deux courants. Dans une dernière partie, nous nous intéressons aux défis juridiques, techniques et épistémologiques que doit relever le linguiste qui cherche à étudier des corpus multimodaux en ligne qui prennent des formes de plus en plus sophistiquées et complexes.

    10. Role of radiation therapy in bladder cancer in the Saguenay-Lac Saint-Jean area

      International Nuclear Information System (INIS)

      Brochet, F.; Barrette, L.R.

      1998-01-01

      Bladder cancer is more frequent in Quebec, especially in Saguenay-Lac Saint-Jean than in other Canadian provinces and in the USA. From 1983 to 1996, only 78 patients presenting with bladder cancer received external beam radiation therapy. Sixty-eight were treated with curative intent Overall survival rates were 70% at 3 years, 66% at 5 years, and 40% at 10 years. Retrospective analysis of these cases and literature review show that preoperative radiation therapy is useful in the management of bladder cancer, especially in T3 tumors. It is also useful for patients whose tumor objectively responds to radiation therapy, without an increase in morbidity. (authors)

    11. Evaluation of critical indicators in the process of acquiring supplies and services LAC-UFPE

      Science.gov (United States)

      Caetano, V. F.; Ferreira, C. V.; dos Santos, M. J.; Honorato, F. A.

      2015-01-01

      In laboratories linked to public universities and accredited by the NBR ISO/IEC 17025, to meet efficiently item 4.6 (procurement of supplies and services) is a challenge that can be accomplished by programming based on historical purchases and services. In this study, we evaluated the critical procurement items to meet the quality management system of the LAC-UFPE: reagents, certified reference material, of equipment parts, maintenance and calibration of equipment and instruments. It was found that the most critical item is the certified reference material, the purchase or repair of which must be expedited within 125 days prior to the receipt to occur within the desired period.

    12. Analysis of spontaneous deletions and gene amplification in the lac region of Escherichia coli

      International Nuclear Information System (INIS)

      Albertini, A.M.; Hofer, M.; Calos, M.P.; Tlsty, T.D.; Miller, J.H.

      1983-01-01

      Spontaneous rearrangements, such as large deletions and duplications, have important implications for the structure of the genome. It is therefore of great interest to analyze these events at the molecular level. We have constructed derivatives of a lacI-Z fusion strain, which allow us to study deletions in a more systematic manner than was previously possible. These derivatives have been used to investigate how frequently larger deletions (> 700 bp) occur between short homologies on both recA and recA - strains and to determine the effect of the lengths of the short homologies and of the distance between homologies on the frequency of deletion formation. 38 references, 11 figures

    13. Geology and age of the Lac a la Perdrix fenite, southern Gatineau district, Quebec

      International Nuclear Information System (INIS)

      Hogarth, D.D.

      1996-01-01

      The Lac a Ia Perdrix fenite lies in the Central Metasedimentary Belt of the Grenville Province. This 30 m wide fenite, adjacent to a narrow calciocarbonatite sill, replaces diopside-oligoclase gneiss and is composed of magnesio-arfvedsonite, aegirine, microcline, albite, and fluorapatite. Near the contact with carbonatite, it contains appreciable monazite and barite whereas aegirine virtually disappears. Fenitization probably took place early in the igneous stage of carbonatite development. A Pb/U monazite age of 1026 ± 2 Ma is thought to date fenite formation. Together with published data, this age shows that carbonatite intruded metamorphic rocks near the close of the Grenville Orogeny. (author). 33 refs., 4 tabs., 5 figs

    14. Geology and age of the Lac a la Perdrix fenite, southern Gatineau district, Quebec

      Energy Technology Data Exchange (ETDEWEB)

      Hogarth, D D [Ottawa Univ., ON (Canada). Dept. of Geology; VanBreemen, O [Geological Survey of Canada, Ottawa, ON (Canada)

      1997-12-31

      The Lac a Ia Perdrix fenite lies in the Central Metasedimentary Belt of the Grenville Province. This 30 m wide fenite, adjacent to a narrow calciocarbonatite sill, replaces diopside-oligoclase gneiss and is composed of magnesio-arfvedsonite, aegirine, microcline, albite, and fluorapatite. Near the contact with carbonatite, it contains appreciable monazite and barite whereas aegirine virtually disappears. Fenitization probably took place early in the igneous stage of carbonatite development. A Pb/U monazite age of 1026 {+-} 2 Ma is thought to date fenite formation. Together with published data, this age shows that carbonatite intruded metamorphic rocks near the close of the Grenville Orogeny. (author). 33 refs., 4 tabs., 5 figs.

    15. Effects of mineral water from spring 3 in Băile Tuşnad on experimentally induced alcoholic liver disease

      Directory of Open Access Journals (Sweden)

      Gabriela Dogaru

      2017-05-01

      Full Text Available Chronic alcohol consumption leads to the development of specific disorders, particularly of the liver. In this study, we aimed to investigate by optical microscopy the hepatic changes occurring after administration of ethyl alcohol for 70 days to Wistar rats, as well as the curative effect of mineral water from spring 3 in Băile Tuşnad administered for 50 days after completion of ethyl alcohol administration. Liver fragments were harvested and histologically processed by paraffin embedding and stained with Goldner’s trichrome method. After the first 70 days of the experiment, in the liver parenchyma, fat loading of hepatocytes and mild perivascular fibrosis were identified. After another 50 days, during which some of the rats drank tap water, the pathological evolution did not seem to stop, but on the contrary, a slight aggravation could be observed, while in rats drinking Tuşnad mineral water there was an arrest of evolution and a slight regression of the described aspects. This study evidences the curative effect of mineral water from spring 3 in Băile Tuşnad on alcoholic liver disease.

    16. Thermal comfort characteristics of some selected building materials in the regional setting of Ile-Ife, Nigeria

      Directory of Open Access Journals (Sweden)

      S. K. Fasogbon

      2015-07-01

      Full Text Available In Ile-Ife, it is very common to see quite a lot of local people engaging in mud bricks moulding, concrete block making, mud house construction and the bricklaying profession in general. These have particular bearing on the economy and the political situation of the people involved as in the profession there is set of rules and regulations guiding the rate and procedure for carrying out any such moulding or construction work. Considering the importance of this, the present study investigated the thermal performance of some selected building materials in the ancient city of Ile-Ife in Nigeria. The work demonstrated how a building envelope responds to outdoor conditions through graphic illustrations. This was followed by constructing three physical building models, with model 1 constructed of mud bricks, model 2 constructed of concrete blocks and model 3 constructed of cast concrete. Each of the models was first roofed with galvanised Iron roofing sheets, later with aluminium roofing sheets and finally with asbestos roofing. Readings were taken by inserting TGP-4500 Data loggers into appropriate positions. The results showed that internal temperatures in the mud-brick and cast concrete buildings remained fairly stable despite external diurnal fluctuations. Humidity data collected also showed that fluctuations in external humidity levels do not affect humidity levels within the mud-brick and cast concrete structures significantly. On the other hand, the structure made of concrete blocks responded more to external fluctuations in temperature and humidity. Moreover, humidity levels in the cast concrete building were the least, followed by those in the mud-brick house; while the concrete block structure had the highest level of humidity. It was also discovered that aluminium roofing gave the highest internal temperature, followed by galvanised iron roofing and the least was seen with asbestos roofing. For external diurnal fluctuations, building model

    17. Appel à manifestation d'intérêt : Développement des capacités des ...

      International Development Research Centre (IDRC) Digital Library (Canada)

      Les think tanks fournissent des extrants de recherche aux responsables des politiques, créent des espaces pour les débats publics et mobilisent différents publics et ... ainsi que les activités de renforcement institutionnel telles que la planification stratégique, les ressources humaines, la gestion financière et la vérification.

    18. Influence of the salting time on volatile compounds during the manufacture of dry-cured pork shoulder "lacón".

      Science.gov (United States)

      Purriños, Laura; Franco, Daniel; Carballo, Javier; Lorenzo, José M

      2012-12-01

      The effect of the length of salting time on volatile compounds throughout the manufacture of dry-cured "lacón" was studied using a purge-and-trap extraction and GC/MS analysis. For this study, six treatments of "lacón" were salted with different amounts of salt (LS (3 days of salting), MS (4 days of salting) and HS (5 days of salting)). The total area of volatile compounds increased significantly (Psalting time increased. Significant differences were found for the total area of all aldehydes for each salting time at the end of process. Hexanal presented the most relative abundance, showing highest content in HS treatments while LS treatments showed the lowest one at the end of salting, post-salting and drying-ripening stage. The influence of salting time on the content of 3-Octen-2-one was significant on salting stage (Psalting time affected (Psalting and at the end of drying-ripening stage. The salting time affected significantly (Psalt level (P>0.05) was detected on total hydrocarbons and total furans at the end of process. Copyright © 2012 Elsevier Ltd. All rights reserved.

    19. The energy issue in drinking water facilities. Assessment for the reduction of energy consumption and for the use of renewable energy within the Syndicat des eaux d'lle-de-France

      International Nuclear Information System (INIS)

      Lang, A.; Guery, B.; Ferrari, J.P.; HABART, M.

      2013-01-01

      The energy challenges for the Syndicat des eaux d'Ile-de-France (Sedif), the biggest drinking water utility in France, are particularly significant, since its facilities for the production and distribution of drinking water, in particular the pumping station, consume the electrical equivalent of a town of 25,000 inhabitants (ca. 200 GWh per year). This consumption generates 15,700 tonnes in CO 2 equivalent annually. Furthermore, the Sedif area has numerous sites with a strong potential for the production of renewable energy: 21 photovoltaic, 4 wind, 15 geothermal and 10 close to a heating network. In order to meet these challenges, the Sedif wishes to integrate into its energy policy, the EU targets to reduce greenhouse gas (GHG) emissions by 20%, to increase energy efficiency by 20% and to increase the share of renewable energy to 20% of its overall consumption between now and 2020. In order to do this, the public utility has set these targets for the one part, within the scope of its project ownership and for the other part, within that of the operations delegated to Veolia Eau d'Ile-de-France SNC. The energy consumption of 20 sites, which are undergoing renovation work between 2011 and 2015, will be better controlled, through the installation of high-efficiency motors or transformers and the replacement of thermal ozone destructors. Five pilot projects to produce or use renewable energy have been undertaken since 2010: the implementation of photovoltaic installations for power production on the main units' roofs, the installation of photovoltaic panels on the tanks at Chatillon and on the new tank at Villejuif, the erection of a wind turbine on the new tank at Palaiseau, and the replacement of the heating systems in the production plant at Choisy-le-Roi. The remaining improvement levers are those that Sedif is imposing on its delegates, Veolia Eau d'Ile-de-France SNC, within the framework of a new 12-year contract [from 1 January 2011). (authors)

    20. Modélisation des processus physiques et biologiques dans des fosses septiques et voies de valorisation des boues de vidange:Application à Bujumbura-Burundi

      OpenAIRE

      Nsavyimana, Gaston

      2014-01-01

      Dans les pays en développement (PED) en général et au Burundi en particulier, la problématique de gestion des eaux usées et des déchets solides constitue un enjeu majeur pour les spécialistes et les autorités locales. En effet, suite à un manque des stations d'épuration collectives au Burundi, les fosses septiques sont les plus utilisées pour gérer les eaux usées produites. Cependant, les processus qui s'y déroulent ne sont pas encore maîtrisés et la gestion des boues de vidange lorsque c...